-- dump date 20140619_085438 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 1133852000001 SEQ_END SEQ_END NC_018658.1 5273097 5273097 DR NC_018658.1; contig end 5273097..5273097 Escherichia coli O104:H4 str. 2011C-3493 1133852000002 SEQ_END SEQ_END NC_018659.1 88544 88544 DR NC_018659.1; contig end 88544..88544 Escherichia coli O104:H4 str. 2011C-3493 1133852000003 SEQ_END SEQ_END NC_018660.1 1549 1549 DR NC_018660.1; contig end 1549..1549 Escherichia coli O104:H4 str. 2011C-3493 1133852000004 SEQ_END SEQ_END NC_018666.1 74217 74217 DR NC_018666.1; contig end 74217..74217 Escherichia coli O104:H4 str. 2011C-3493 YP_006776737.1 CDS dnaA NC_018658.1 33 1436 D COG0593 ATPase involved in DNA replication initiation; chromosomal replication initiation protein 33..1436 Escherichia coli O104:H4 str. 2011C-3493 13700294 YP_006776738.1 CDS O3K_00010 NC_018658.1 1441 2541 D COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase III subunit beta 1441..2541 Escherichia coli O104:H4 str. 2011C-3493 13698670 YP_006776739.1 CDS recF NC_018658.1 2541 3614 D COG1195 Recombinational DNA repair ATPase (RecF pathway); recombination protein F 2541..3614 Escherichia coli O104:H4 str. 2011C-3493 13698671 YP_006776740.1 CDS gyrB NC_018658.1 3643 6057 D COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA gyrase subunit B 3643..6057 Escherichia coli O104:H4 str. 2011C-3493 13698672 YP_006776741.1 CDS O3K_00025 NC_018658.1 6077 6277 D hypothetical protein 6077..6277 Escherichia coli O104:H4 str. 2011C-3493 13698673 YP_006776742.1 CDS O3K_00030 NC_018658.1 6297 6695 D COG3753 Uncharacterized protein conserved in bacteria; hypothetical protein 6297..6695 Escherichia coli O104:H4 str. 2011C-3493 13698674 YP_006776743.1 CDS O3K_00035 NC_018658.1 6810 7622 D COG0561 Predicted hydrolases of the HAD superfamily; sugar phosphate phosphatase 6810..7622 Escherichia coli O104:H4 str. 2011C-3493 13698675 YP_006776744.1 CDS O3K_00040 NC_018658.1 7668 8324 R hypothetical protein complement(7668..8324) Escherichia coli O104:H4 str. 2011C-3493 13698676 YP_006776745.1 CDS O3K_00045 NC_018658.1 8602 9291 D COG2186 Transcriptional regulators; putative DNA-binding transcriptional regulator 8602..9291 Escherichia coli O104:H4 str. 2011C-3493 13698677 YP_006776746.1 CDS O3K_00050 NC_018658.1 9288 10166 D COG3734 2-keto-3-deoxy-galactonokinase; 2-oxo-3-deoxygalactonate kinase 9288..10166 Escherichia coli O104:H4 str. 2011C-3493 13698678 YP_006776747.1 CDS O3K_00055 NC_018658.1 10150 10767 D COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 10150..10767 Escherichia coli O104:H4 str. 2011C-3493 13698679 YP_006776748.1 CDS O3K_00060 NC_018658.1 10764 11912 D COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; galactonate dehydratase 10764..11912 Escherichia coli O104:H4 str. 2011C-3493 13698680 YP_006776749.1 CDS O3K_00065 NC_018658.1 12032 13324 D COG0477 Permeases of the major facilitator superfamily; D-galactonate transporter 12032..13324 Escherichia coli O104:H4 str. 2011C-3493 13698681 YP_006776750.1 CDS O3K_00070 NC_018658.1 13321 14385 R COG0644 Dehydrogenases (flavoproteins); oxidoreductase complement(13321..14385) Escherichia coli O104:H4 str. 2011C-3493 13698682 YP_006776751.1 CDS O3K_00075 NC_018658.1 14486 15700 D COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; hypothetical protein 14486..15700 Escherichia coli O104:H4 str. 2011C-3493 13698683 YP_006776752.1 CDS O3K_00080 NC_018658.1 15702 16034 R COG5645 Predicted periplasmic lipoprotein; hypothetical protein complement(15702..16034) Escherichia coli O104:H4 str. 2011C-3493 13698684 YP_006776753.1 CDS O3K_00085 NC_018658.1 16340 16753 D COG0071 Molecular chaperone (small heat shock protein); heat shock protein IbpA 16340..16753 Escherichia coli O104:H4 str. 2011C-3493 13698685 YP_006776754.1 CDS O3K_00090 NC_018658.1 16865 17293 D COG0071 Molecular chaperone (small heat shock protein); heat shock chaperone IbpB 16865..17293 Escherichia coli O104:H4 str. 2011C-3493 13698686 YP_006776755.1 CDS O3K_00095 NC_018658.1 17490 19151 D COG2985 Predicted permease; transporter 17490..19151 Escherichia coli O104:H4 str. 2011C-3493 13698687 YP_006776756.1 CDS O3K_00100 NC_018658.1 19148 19864 R COG2188 Transcriptional regulators; putative DNA-binding transcriptional regulator complement(19148..19864) Escherichia coli O104:H4 str. 2011C-3493 13698688 YP_006776757.1 CDS O3K_00105 NC_018658.1 20160 21776 D COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system arbutin-like transporter subunit IIC 20160..21776 Escherichia coli O104:H4 str. 2011C-3493 13698689 YP_006776758.1 CDS O3K_00110 NC_018658.1 21776 22414 D COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; 6-phospho-beta-glucosidase 21776..22414 Escherichia coli O104:H4 str. 2011C-3493 13698690 YP_006776759.1 CDS O3K_00115 NC_018658.1 22414 22590 D COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; glycoside hydrolase 22414..22590 Escherichia coli O104:H4 str. 2011C-3493 13698691 YP_006776760.1 CDS O3K_00120 NC_018658.1 22587 23510 R COG2207 AraC-type DNA-binding domain-containing proteins; putative DNA-binding transcriptional regulator complement(22587..23510) Escherichia coli O104:H4 str. 2011C-3493 13698692 YP_006776761.1 CDS O3K_00125 NC_018658.1 23647 25362 D COG4146 Predicted symporter; transporter 23647..25362 Escherichia coli O104:H4 str. 2011C-3493 13698693 YP_006776762.1 CDS O3K_00130 NC_018658.1 25359 26852 D COG3119 Arylsulfatase A and related enzymes; putative sulfatase/phosphatase 25359..26852 Escherichia coli O104:H4 str. 2011C-3493 13698694 YP_006776763.1 CDS O3K_00135 NC_018658.1 26899 27348 R inner membrane protein complement(26899..27348) Escherichia coli O104:H4 str. 2011C-3493 13698695 YP_006776764.1 CDS O3K_00140 NC_018658.1 27457 27804 D COG2149 Predicted membrane protein; inner membrane protein YidH 27457..27804 Escherichia coli O104:H4 str. 2011C-3493 13698696 YP_006776765.1 CDS O3K_00145 NC_018658.1 27794 28156 D hypothetical protein 27794..28156 Escherichia coli O104:H4 str. 2011C-3493 13698697 YP_006776766.1 CDS O3K_00150 NC_018658.1 28153 28650 D COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); transcriptional regulator 28153..28650 Escherichia coli O104:H4 str. 2011C-3493 13698698 YP_006776767.1 CDS emrD NC_018658.1 28658 29842 R COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein D complement(28658..29842) Escherichia coli O104:H4 str. 2011C-3493 13698699 YP_006776768.1 CDS O3K_00160 NC_018658.1 30261 30350 R toxic peptide TisB complement(30261..30350) Escherichia coli O104:H4 str. 2011C-3493 13698700 YP_006776769.1 CDS O3K_00165 NC_018658.1 30638 31120 R hypothetical protein complement(30638..31120) Escherichia coli O104:H4 str. 2011C-3493 13698701 YP_006776770.1 CDS O3K_00170 NC_018658.1 31119 32807 D COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase catalytic subunit 31119..32807 Escherichia coli O104:H4 str. 2011C-3493 13698702 YP_006776771.1 CDS O3K_00175 NC_018658.1 32811 33101 D COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase 1 regulatory subunit 32811..33101 Escherichia coli O104:H4 str. 2011C-3493 13698703 YP_006776772.1 CDS O3K_00180 NC_018658.1 33176 33766 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator UhpA 33176..33766 Escherichia coli O104:H4 str. 2011C-3493 13698704 YP_006776773.1 CDS O3K_00185 NC_018658.1 33766 35268 D COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific; sensory histidine kinase UhpB 33766..35268 Escherichia coli O104:H4 str. 2011C-3493 13698705 YP_006776774.1 CDS O3K_00190 NC_018658.1 35278 36597 D COG2271 Sugar phosphate permease; regulatory protein UhpC 35278..36597 Escherichia coli O104:H4 str. 2011C-3493 13698706 YP_006776775.1 CDS uhpT NC_018658.1 36735 38126 D COG2271 Sugar phosphate permease; sugar phosphate antiporter 36735..38126 Escherichia coli O104:H4 str. 2011C-3493 13698707 YP_006776776.1 CDS O3K_00200 NC_018658.1 38171 39937 R COG1001 Adenine deaminase; cryptic adenine deaminase complement(38171..39937) Escherichia coli O104:H4 str. 2011C-3493 13698708 YP_006776777.1 CDS O3K_00205 NC_018658.1 40112 41446 D COG2252 Permeases; hypothetical protein 40112..41446 Escherichia coli O104:H4 str. 2011C-3493 13698709 YP_006776778.1 CDS O3K_00210 NC_018658.1 41499 41951 D COG0442 Prolyl-tRNA synthetase; hypothetical protein 41499..41951 Escherichia coli O104:H4 str. 2011C-3493 13698710 YP_006776779.1 CDS nepI NC_018658.1 42162 43346 D COG2814 Arabinose efflux permease; ribonucleoside transporter 42162..43346 Escherichia coli O104:H4 str. 2011C-3493 13698711 YP_006776780.1 CDS O3K_00220 NC_018658.1 43387 43680 R hypothetical protein complement(43387..43680) Escherichia coli O104:H4 str. 2011C-3493 13698712 YP_006776781.1 CDS O3K_00225 NC_018658.1 43685 43804 R hypothetical protein complement(43685..43804) Escherichia coli O104:H4 str. 2011C-3493 13698713 YP_006776782.1 CDS O3K_00230 NC_018658.1 43902 44720 D COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; hypothetical protein 43902..44720 Escherichia coli O104:H4 str. 2011C-3493 13698714 YP_006776783.1 CDS O3K_00235 NC_018658.1 44724 45647 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein complement(44724..45647) Escherichia coli O104:H4 str. 2011C-3493 13698715 YP_006776784.1 CDS O3K_00240 NC_018658.1 45758 46942 R COG0477 Permeases of the major facilitator superfamily; sugar efflux system complement(45758..46942) Escherichia coli O104:H4 str. 2011C-3493 13698716 YP_006776785.1 CDS O3K_00245 NC_018658.1 47324 47473 R COG3943 Virulence protein; hypothetical protein complement(47324..47473) Escherichia coli O104:H4 str. 2011C-3493 13698717 YP_006776786.1 CDS O3K_00250 NC_018658.1 47735 48580 R hypothetical protein complement(47735..48580) Escherichia coli O104:H4 str. 2011C-3493 13698718 YP_006776787.1 CDS O3K_00255 NC_018658.1 48665 48862 R hypothetical protein complement(48665..48862) Escherichia coli O104:H4 str. 2011C-3493 13698719 YP_006776788.1 CDS O3K_00260 NC_018658.1 48882 49370 R hypothetical protein complement(48882..49370) Escherichia coli O104:H4 str. 2011C-3493 13698720 YP_006776789.1 CDS O3K_00265 NC_018658.1 49367 49744 R hypothetical protein complement(49367..49744) Escherichia coli O104:H4 str. 2011C-3493 13698721 YP_006776790.1 CDS O3K_00270 NC_018658.1 49791 50168 R hypothetical protein complement(49791..50168) Escherichia coli O104:H4 str. 2011C-3493 13698722 YP_006776791.1 CDS O3K_00275 NC_018658.1 50218 50331 R hypothetical protein complement(50218..50331) Escherichia coli O104:H4 str. 2011C-3493 13698723 YP_006776792.1 CDS O3K_00280 NC_018658.1 50331 50552 R hypothetical protein complement(50331..50552) Escherichia coli O104:H4 str. 2011C-3493 13698724 YP_006776793.1 CDS O3K_00285 NC_018658.1 50615 51091 R COG2003 DNA repair proteins; putative DNA repair protein complement(50615..51091) Escherichia coli O104:H4 str. 2011C-3493 13698725 YP_006776794.1 CDS O3K_00290 NC_018658.1 51107 51580 R hypothetical protein complement(51107..51580) Escherichia coli O104:H4 str. 2011C-3493 13698726 YP_006776795.1 CDS O3K_00295 NC_018658.1 51746 51919 R antirestriction protein complement(51746..51919) Escherichia coli O104:H4 str. 2011C-3493 13698727 YP_006776796.1 CDS O3K_00300 NC_018658.1 51919 52737 R hypothetical protein complement(51919..52737) Escherichia coli O104:H4 str. 2011C-3493 13698728 YP_006776797.1 CDS O3K_00305 NC_018658.1 52892 53050 R hypothetical protein complement(52892..53050) Escherichia coli O104:H4 str. 2011C-3493 13698729 YP_006776798.1 CDS O3K_00310 NC_018658.1 53121 55967 R COG5295 Autotransporter adhesin; antigen 43 precursor (AG43, Fluffing protein) complement(53121..55967) Escherichia coli O104:H4 str. 2011C-3493 13698730 YP_006776799.1 CDS O3K_00315 NC_018658.1 56340 57212 R COG3596 Predicted GTPase; hypothetical protein complement(56340..57212) Escherichia coli O104:H4 str. 2011C-3493 13698731 YP_006776800.1 CDS O3K_00320 NC_018658.1 57311 58183 R hypothetical protein complement(57311..58183) Escherichia coli O104:H4 str. 2011C-3493 13698732 YP_006776801.1 CDS O3K_00325 NC_018658.1 59826 60038 R COG1484 DNA replication protein; IstB ATP binding domain-containing protein complement(59826..60038) Escherichia coli O104:H4 str. 2011C-3493 13698733 YP_006776802.1 CDS O3K_00330 NC_018658.1 60671 60868 D hypothetical protein 60671..60868 Escherichia coli O104:H4 str. 2011C-3493 13698734 YP_006776803.1 CDS O3K_00335 NC_018658.1 60771 61379 R hypothetical protein complement(60771..61379) Escherichia coli O104:H4 str. 2011C-3493 13698735 YP_006776804.1 CDS O3K_00340 NC_018658.1 61468 61674 R COG3311 Predicted transcriptional regulator; putative Prophage CP4-57 regulatory protein complement(61468..61674) Escherichia coli O104:H4 str. 2011C-3493 13698736 YP_006776805.1 CDS O3K_00345 NC_018658.1 62453 62593 D hemolysin expression modulating protein 62453..62593 Escherichia coli O104:H4 str. 2011C-3493 13698737 YP_006776806.1 CDS O3K_00350 NC_018658.1 62649 62795 D hypothetical protein 62649..62795 Escherichia coli O104:H4 str. 2011C-3493 13698738 YP_006776807.1 CDS O3K_00355 NC_018658.1 63337 63906 D hypothetical protein 63337..63906 Escherichia coli O104:H4 str. 2011C-3493 13698739 YP_006776808.1 CDS O3K_00360 NC_018658.1 64072 64455 D COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 64072..64455 Escherichia coli O104:H4 str. 2011C-3493 13698740 YP_006776809.1 CDS O3K_00365 NC_018658.1 64452 64661 D hypothetical protein 64452..64661 Escherichia coli O104:H4 str. 2011C-3493 13698741 YP_006776810.1 CDS O3K_00370 NC_018658.1 65208 65915 D COG2801 Transposase and inactivated derivatives; transposase 65208..65915 Escherichia coli O104:H4 str. 2011C-3493 13698742 YP_006776811.1 CDS O3K_00375 NC_018658.1 65900 66760 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; transporter permease 65900..66760 Escherichia coli O104:H4 str. 2011C-3493 13698743 YP_006776812.1 CDS O3K_00380 NC_018658.1 66792 68066 R COG0477 Permeases of the major facilitator superfamily; tetracycline efflux protein complement(66792..68066) Escherichia coli O104:H4 str. 2011C-3493 13698744 YP_006776813.1 CDS O3K_00385 NC_018658.1 68070 68747 D COG1309 Transcriptional regulator; tetracycline repressor protein 68070..68747 Escherichia coli O104:H4 str. 2011C-3493 13698745 YP_006776814.1 CDS O3K_00390 NC_018658.1 68779 69021 R transposase complement(68779..69021) Escherichia coli O104:H4 str. 2011C-3493 13698746 YP_006776815.1 CDS O3K_00395 NC_018658.1 68944 69108 D hypothetical protein 68944..69108 Escherichia coli O104:H4 str. 2011C-3493 13698747 YP_006776816.1 CDS O3K_00400 NC_018658.1 69317 69433 D hypothetical protein 69317..69433 Escherichia coli O104:H4 str. 2011C-3493 13698748 YP_006776817.1 CDS O3K_00405 NC_018658.1 69893 71005 D COG3385 FOG: Transposase and inactivated derivatives; putative transposase insL for insertion sequence IS186 69893..71005 Escherichia coli O104:H4 str. 2011C-3493 13698749 YP_006776818.1 CDS O3K_00410 NC_018658.1 71373 71807 R COG0789 Predicted transcriptional regulators; putative transcriptional regulator MerR complement(71373..71807) Escherichia coli O104:H4 str. 2011C-3493 13698750 YP_006776819.1 CDS O3K_00415 NC_018658.1 71879 72229 D putative mercuric transport protein 71879..72229 Escherichia coli O104:H4 str. 2011C-3493 13698751 YP_006776820.1 CDS O3K_00420 NC_018658.1 72243 72518 D COG2608 Copper chaperone; mercury resistance operon protein MerP 72243..72518 Escherichia coli O104:H4 str. 2011C-3493 13698752 YP_006776821.1 CDS O3K_00425 NC_018658.1 72554 72976 D putative mercury transport protein MerC 72554..72976 Escherichia coli O104:H4 str. 2011C-3493 13698753 YP_006776822.1 CDS O3K_00430 NC_018658.1 73028 74722 D COG2608 Copper chaperone; putative mercuric reductase 73028..74722 Escherichia coli O104:H4 str. 2011C-3493 13698754 YP_006776823.1 CDS O3K_00435 NC_018658.1 74740 75102 D COG0789 Predicted transcriptional regulators; transcriptional regulator MerD 74740..75102 Escherichia coli O104:H4 str. 2011C-3493 13698755 YP_006776824.1 CDS O3K_00440 NC_018658.1 75099 75335 D putative mercury resistance protein 75099..75335 Escherichia coli O104:H4 str. 2011C-3493 13698756 YP_006776825.1 CDS O3K_00445 NC_018658.1 75332 76039 D COG2200 FOG: EAL domain; hypothetical protein 75332..76039 Escherichia coli O104:H4 str. 2011C-3493 13698757 YP_006776826.1 CDS O3K_00450 NC_018658.1 76078 77382 D COG2801 Transposase and inactivated derivatives; TniA protein 76078..77382 Escherichia coli O104:H4 str. 2011C-3493 13698758 YP_006776827.1 CDS O3K_00455 NC_018658.1 77429 78133 D COG3316 Transposase and inactivated derivatives; transposase 77429..78133 Escherichia coli O104:H4 str. 2011C-3493 13698759 YP_006776828.1 CDS O3K_00460 NC_018658.1 78194 79030 R COG3570 Streptomycin 6-kinase; streptomycin phosphotransferase complement(78194..79030) Escherichia coli O104:H4 str. 2011C-3493 13698760 YP_006776829.1 CDS O3K_00465 NC_018658.1 79030 79833 R COG3231 Aminoglycoside phosphotransferase; hypothetical protein complement(79030..79833) Escherichia coli O104:H4 str. 2011C-3493 13698761 YP_006776830.1 CDS O3K_00470 NC_018658.1 79894 80709 R COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase complement(79894..80709) Escherichia coli O104:H4 str. 2011C-3493 13698762 YP_006776831.1 CDS O3K_00475 NC_018658.1 81017 81868 R replication protein C complement(81017..81868) Escherichia coli O104:H4 str. 2011C-3493 13698763 YP_006776832.1 CDS O3K_00480 NC_018658.1 81855 82562 R COG3598 RecA-family ATPase; replication protein A complement(81855..82562) Escherichia coli O104:H4 str. 2011C-3493 13698764 YP_006776833.1 CDS O3K_00485 NC_018658.1 82624 83328 R COG3316 Transposase and inactivated derivatives; transposase complement(82624..83328) Escherichia coli O104:H4 str. 2011C-3493 13698765 YP_006776834.1 CDS O3K_00490 NC_018658.1 83453 84157 D COG3316 Transposase and inactivated derivatives; transposase 83453..84157 Escherichia coli O104:H4 str. 2011C-3493 13698766 YP_006776835.1 CDS O3K_00495 NC_018658.1 84191 84970 R COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase complement(84191..84970) Escherichia coli O104:H4 str. 2011C-3493 13698767 YP_006776836.1 CDS O3K_00500 NC_018658.1 84964 85311 R COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein complement(84964..85311) Escherichia coli O104:H4 str. 2011C-3493 13698768 YP_006776837.1 CDS O3K_00505 NC_018658.1 85541 86014 R COG0262 Dihydrofolate reductase; dihydrofolate reductase complement(85541..86014) Escherichia coli O104:H4 str. 2011C-3493 13698769 YP_006776838.1 CDS O3K_00510 NC_018658.1 86172 87185 D COG0582 Integrase; integrase/recombinase 86172..87185 Escherichia coli O104:H4 str. 2011C-3493 13698770 YP_006776839.1 CDS O3K_00515 NC_018658.1 87144 87323 R transcriptional regulator complement(87144..87323) Escherichia coli O104:H4 str. 2011C-3493 13698771 YP_006776840.1 CDS O3K_00520 NC_018658.1 87538 87738 D modulator protein 87538..87738 Escherichia coli O104:H4 str. 2011C-3493 13698772 YP_006776841.1 CDS O3K_00525 NC_018658.1 87864 88424 D COG1961 Site-specific recombinases, DNA invertase Pin homologs; Tn21 resolvase 87864..88424 Escherichia coli O104:H4 str. 2011C-3493 13698773 YP_006776842.1 CDS O3K_00530 NC_018658.1 88427 91393 D COG4644 Transposase and inactivated derivatives, TnpA family; transposase TnpA, Tn21 88427..91393 Escherichia coli O104:H4 str. 2011C-3493 13698774 YP_006776843.1 CDS O3K_00535 NC_018658.1 91460 91549 D acetyltransferase 91460..91549 Escherichia coli O104:H4 str. 2011C-3493 13698775 YP_006776844.1 CDS O3K_00540 NC_018658.1 91583 91858 D COG3677 Transposase and inactivated derivatives; InsA 91583..91858 Escherichia coli O104:H4 str. 2011C-3493 13698776 YP_006776845.1 CDS O3K_00545 NC_018658.1 91777 92280 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 91777..92280 Escherichia coli O104:H4 str. 2011C-3493 13698777 YP_006776846.1 CDS O3K_00550 NC_018658.1 92399 93583 R COG0582 Integrase; hypothetical protein complement(92399..93583) Escherichia coli O104:H4 str. 2011C-3493 13698778 YP_006776847.1 CDS O3K_00555 NC_018658.1 94270 95652 D COG2211 Na+/melibiose symporter and related transporters; transporter 94270..95652 Escherichia coli O104:H4 str. 2011C-3493 13698780 YP_006776848.1 CDS O3K_00560 NC_018658.1 95662 97980 D COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; putative alpha-glucosidase 95662..97980 Escherichia coli O104:H4 str. 2011C-3493 13698781 YP_006776849.1 CDS O3K_00565 NC_018658.1 98033 99742 R hypothetical protein complement(98033..99742) Escherichia coli O104:H4 str. 2011C-3493 13698782 YP_006776850.1 CDS O3K_00570 NC_018658.1 99863 101254 R COG2233 Xanthine/uracil permeases; purine permease yicE complement(99863..101254) Escherichia coli O104:H4 str. 2011C-3493 13698783 YP_006776851.1 CDS O3K_00575 NC_018658.1 101534 102739 D COG0786 Na+/glutamate symporter; sodium/glutamate symporter 101534..102739 Escherichia coli O104:H4 str. 2011C-3493 13698784 YP_006776852.1 CDS O3K_00580 NC_018658.1 102905 104986 R COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG complement(102905..104986) Escherichia coli O104:H4 str. 2011C-3493 13698785 YP_006776853.1 CDS O3K_00585 NC_018658.1 104992 105681 R COG0566 rRNA methylases; tRNA guanosine-2'-O-methyltransferase complement(104992..105681) Escherichia coli O104:H4 str. 2011C-3493 13698786 YP_006776854.1 CDS O3K_00590 NC_018658.1 105688 107796 R COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase complement(105688..107796) Escherichia coli O104:H4 str. 2011C-3493 13698787 YP_006776855.1 CDS rpoZ NC_018658.1 107815 108090 R COG1758 DNA-directed RNA polymerase, subunit K/omega; DNA-directed RNA polymerase subunit omega complement(107815..108090) Escherichia coli O104:H4 str. 2011C-3493 13698788 YP_006776856.1 CDS gmk NC_018658.1 108145 108768 R COG0194 Guanylate kinase; guanylate kinase complement(108145..108768) Escherichia coli O104:H4 str. 2011C-3493 13698789 YP_006776857.1 CDS ligB NC_018658.1 109026 110708 D COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase LigB 109026..110708 Escherichia coli O104:H4 str. 2011C-3493 13698790 YP_006776858.1 CDS O3K_00610 NC_018658.1 110705 111322 R COG2860 Predicted membrane protein; hypothetical protein complement(110705..111322) Escherichia coli O104:H4 str. 2011C-3493 13698791 YP_006776859.1 CDS dinD NC_018658.1 111614 112438 R DNA-damage-inducible protein D complement(111614..112438) Escherichia coli O104:H4 str. 2011C-3493 13698792 YP_006776860.1 CDS O3K_00620 NC_018658.1 112659 113522 R COG1561 Uncharacterized stress-induced protein; hypothetical protein complement(112659..113522) Escherichia coli O104:H4 str. 2011C-3493 13698793 YP_006776861.1 CDS rph NC_018658.1 113649 114365 D COG0689 RNase PH; ribonuclease PH 113649..114365 Escherichia coli O104:H4 str. 2011C-3493 13698794 YP_006776862.1 CDS pyrE NC_018658.1 114431 115072 D COG0461 Orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 114431..115072 Escherichia coli O104:H4 str. 2011C-3493 13698795 YP_006776863.1 CDS slmA NC_018658.1 115109 115705 R COG1309 Transcriptional regulator; division inhibitor protein complement(115109..115705) Escherichia coli O104:H4 str. 2011C-3493 13698796 YP_006776864.1 CDS dut NC_018658.1 115812 116267 R COG0756 dUTPase; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(115812..116267) Escherichia coli O104:H4 str. 2011C-3493 13698797 YP_006776865.1 CDS O3K_00645 NC_018658.1 116248 117468 R COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(116248..117468) Escherichia coli O104:H4 str. 2011C-3493 13698798 YP_006776866.1 CDS O3K_00650 NC_018658.1 117640 118308 D COG2003 DNA repair proteins; hypothetical protein 117640..118308 Escherichia coli O104:H4 str. 2011C-3493 13698799 YP_006776867.1 CDS rpmB NC_018658.1 118525 118761 D COG0227 Ribosomal protein L28; 50S ribosomal protein L28 118525..118761 Escherichia coli O104:H4 str. 2011C-3493 13698800 YP_006776868.1 CDS rpmG NC_018658.1 118782 118949 D COG0267 Ribosomal protein L33; 50S ribosomal protein L33 118782..118949 Escherichia coli O104:H4 str. 2011C-3493 13698801 YP_006776869.1 CDS O3K_00665 NC_018658.1 119047 119856 D COG0266 Formamidopyrimidine-DNA glycosylase; formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase 119047..119856 Escherichia coli O104:H4 str. 2011C-3493 13698802 YP_006776870.1 CDS coaD NC_018658.1 119895 120374 R COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase complement(119895..120374) Escherichia coli O104:H4 str. 2011C-3493 13698803 YP_006776871.1 CDS O3K_00675 NC_018658.1 120382 121659 R COG1519 3-deoxy-D-manno-octulosonic-acid transferase; 3-deoxy-D-manno-octulosonic-acid transferase complement(120382..121659) Escherichia coli O104:H4 str. 2011C-3493 13698804 YP_006776872.1 CDS O3K_00680 NC_018658.1 122072 123130 D COG0859 ADP-heptose:LPS heptosyltransferase; lipopolysaccharide core biosynthesis protein 122072..123130 Escherichia coli O104:H4 str. 2011C-3493 13698805 YP_006776873.1 CDS O3K_00685 NC_018658.1 123127 124251 D COG0438 Glycosyltransferase; glucosyltransferase I RfaG 123127..124251 Escherichia coli O104:H4 str. 2011C-3493 13698806 YP_006776874.1 CDS O3K_00690 NC_018658.1 124244 125041 D COG0515 Serine/threonine protein kinase; lipopolysaccharide core heptose(I) kinase RfaP 124244..125041 Escherichia coli O104:H4 str. 2011C-3493 13698807 YP_006776875.1 CDS O3K_00695 NC_018658.1 125084 126091 D COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,3-galactosyltransferase 125084..126091 Escherichia coli O104:H4 str. 2011C-3493 13698808 YP_006776876.1 CDS O3K_00700 NC_018658.1 126117 126824 D COG0515 Serine/threonine protein kinase; lipopolysaccharide core biosynthesis protein 126117..126824 Escherichia coli O104:H4 str. 2011C-3493 13698809 YP_006776877.1 CDS O3K_00705 NC_018658.1 126849 127862 D COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glucosyltransferase 126849..127862 Escherichia coli O104:H4 str. 2011C-3493 13698810 YP_006776878.1 CDS O3K_00710 NC_018658.1 127871 129013 D COG0438 Glycosyltransferase; lipopolysaccharide 1,2-N-acetylglucosaminetransferase 127871..129013 Escherichia coli O104:H4 str. 2011C-3493 13698811 YP_006776879.1 CDS O3K_00715 NC_018658.1 129049 130257 R COG3307 Lipid A core - O-antigen ligase and related enzymes; O-antigen ligase RfaL complement(129049..130257) Escherichia coli O104:H4 str. 2011C-3493 13698812 YP_006776880.1 CDS O3K_00720 NC_018658.1 130254 131246 R COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose--LPS heptosyltransferase complement(130254..131246) Escherichia coli O104:H4 str. 2011C-3493 13698813 YP_006776881.1 CDS O3K_00725 NC_018658.1 131250 132296 R COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose--LPS heptosyltransferase complement(131250..132296) Escherichia coli O104:H4 str. 2011C-3493 13698814 YP_006776882.1 CDS rfaD NC_018658.1 132306 133238 R COG0451 Nucleoside-diphosphate-sugar epimerases; ADP-L-glycero-D-manno-heptose-6-epimerase complement(132306..133238) Escherichia coli O104:H4 str. 2011C-3493 13698815 YP_006776883.1 CDS O3K_00735 NC_018658.1 133542 134399 D hypothetical protein 133542..134399 Escherichia coli O104:H4 str. 2011C-3493 13698816 YP_006776884.1 CDS O3K_00740 NC_018658.1 134674 135870 D COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 2-amino-3-ketobutyrate coenzyme A ligase 134674..135870 Escherichia coli O104:H4 str. 2011C-3493 13698817 YP_006776885.1 CDS tdh NC_018658.1 135880 136905 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; L-threonine 3-dehydrogenase 135880..136905 Escherichia coli O104:H4 str. 2011C-3493 13698818 YP_006776886.1 CDS O3K_00750 NC_018658.1 137144 138178 D COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyl transferase 137144..138178 Escherichia coli O104:H4 str. 2011C-3493 13698819 YP_006776887.1 CDS O3K_00755 NC_018658.1 138165 139124 R COG2861 Uncharacterized protein conserved in bacteria; putative polysaccharide deacetylase complement(138165..139124) Escherichia coli O104:H4 str. 2011C-3493 13698820 YP_006776888.1 CDS O3K_00760 NC_018658.1 139128 140411 R COG4942 Membrane-bound metallopeptidase; AmiB activator complement(139128..140411) Escherichia coli O104:H4 str. 2011C-3493 13698821 YP_006776889.1 CDS O3K_00765 NC_018658.1 140421 141965 R COG0696 Phosphoglyceromutase; phosphoglyceromutase complement(140421..141965) Escherichia coli O104:H4 str. 2011C-3493 13698822 YP_006776890.1 CDS O3K_00770 NC_018658.1 142210 142641 D COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 142210..142641 Escherichia coli O104:H4 str. 2011C-3493 13698823 YP_006776891.1 CDS O3K_00775 NC_018658.1 142783 143034 D COG0695 Glutaredoxin and related proteins; glutaredoxin 3 142783..143034 Escherichia coli O104:H4 str. 2011C-3493 13698824 YP_006776892.1 CDS O3K_00780 NC_018658.1 143097 143564 D COG1952 Preprotein translocase subunit SecB; preprotein translocase subunit SecB 143097..143564 Escherichia coli O104:H4 str. 2011C-3493 13698825 YP_006776893.1 CDS gpsA NC_018658.1 143564 144583 D COG0240 Glycerol-3-phosphate dehydrogenase; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 143564..144583 Escherichia coli O104:H4 str. 2011C-3493 13698826 YP_006776894.1 CDS cysE NC_018658.1 144663 145484 D COG1045 Serine acetyltransferase; serine acetyltransferase 144663..145484 Escherichia coli O104:H4 str. 2011C-3493 13698827 YP_006776895.1 CDS O3K_00795 NC_018658.1 145537 146010 R COG0219 Predicted rRNA methylase (SpoU class); putative rRNA methylase complement(145537..146010) Escherichia coli O104:H4 str. 2011C-3493 13698828 YP_006776896.1 CDS lldD NC_018658.1 146196 147386 R COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase complement(146196..147386) Escherichia coli O104:H4 str. 2011C-3493 13698829 YP_006776897.1 CDS O3K_00805 NC_018658.1 147383 148159 R COG2186 Transcriptional regulators; DNA-binding transcriptional repressor LldR complement(147383..148159) Escherichia coli O104:H4 str. 2011C-3493 13698830 YP_006776898.1 CDS O3K_00810 NC_018658.1 148159 149814 R COG1620 L-lactate permease; L-lactate permease complement(148159..149814) Escherichia coli O104:H4 str. 2011C-3493 13698831 YP_006776899.1 CDS O3K_00815 NC_018658.1 150183 155033 R COG5295 Autotransporter adhesin; adhesin complement(150183..155033) Escherichia coli O104:H4 str. 2011C-3493 13698832 YP_006776900.1 CDS O3K_00820 NC_018658.1 155077 155760 R hypothetical protein complement(155077..155760) Escherichia coli O104:H4 str. 2011C-3493 13698833 YP_006776901.1 CDS O3K_00825 NC_018658.1 156304 156666 R hypothetical protein complement(156304..156666) Escherichia coli O104:H4 str. 2011C-3493 13698834 YP_006776902.1 CDS O3K_00830 NC_018658.1 156951 157160 D hypothetical protein 156951..157160 Escherichia coli O104:H4 str. 2011C-3493 13698835 YP_006776903.1 CDS mtlR NC_018658.1 157172 157759 R COG3722 Transcriptional regulator; mannitol repressor protein complement(157172..157759) Escherichia coli O104:H4 str. 2011C-3493 13698836 YP_006776904.1 CDS O3K_00840 NC_018658.1 157759 158907 R COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannitol-1-phosphate 5-dehydrogenase complement(157759..158907) Escherichia coli O104:H4 str. 2011C-3493 13698837 YP_006776905.1 CDS O3K_00845 NC_018658.1 159137 161050 R COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system mannitol-specific transporter subunit IICBA complement(159137..161050) Escherichia coli O104:H4 str. 2011C-3493 13698838 YP_006776906.1 CDS O3K_00850 NC_018658.1 161587 161949 D hypothetical protein 161587..161949 Escherichia coli O104:H4 str. 2011C-3493 13698839 YP_006776907.1 CDS O3K_00855 NC_018658.1 161952 163088 D COG1566 Multidrug resistance efflux pump; hypothetical protein 161952..163088 Escherichia coli O104:H4 str. 2011C-3493 13698840 YP_006776908.1 CDS O3K_00860 NC_018658.1 164687 165148 R COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein complement(164687..165148) Escherichia coli O104:H4 str. 2011C-3493 13698841 YP_006776909.1 CDS O3K_00865 NC_018658.1 165160 166104 R COG3209 Rhs family protein; rhsA core protein with extension complement(165160..166104) Escherichia coli O104:H4 str. 2011C-3493 13698842 YP_006776910.1 CDS O3K_00870 NC_018658.1 166146 166988 R COG1413 FOG: HEAT repeat; putative lyase complement(166146..166988) Escherichia coli O104:H4 str. 2011C-3493 13698843 YP_006776911.1 CDS O3K_00875 NC_018658.1 167093 167476 R hypothetical protein complement(167093..167476) Escherichia coli O104:H4 str. 2011C-3493 13698844 YP_006776912.1 CDS O3K_00880 NC_018658.1 167718 171683 R COG3209 Rhs family protein; rhsB element core protein RshB complement(167718..171683) Escherichia coli O104:H4 str. 2011C-3493 13698845 YP_006776913.1 CDS O3K_00885 NC_018658.1 171912 172520 D COG0625 Glutathione S-transferase; putative glutathione S-transferase 171912..172520 Escherichia coli O104:H4 str. 2011C-3493 13698846 YP_006776914.1 CDS O3K_00890 NC_018658.1 172618 174009 D COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; selenocysteine synthase 172618..174009 Escherichia coli O104:H4 str. 2011C-3493 13698847 YP_006776915.1 CDS O3K_00895 NC_018658.1 174006 175850 D COG3276 Selenocysteine-specific translation elongation factor; selenocysteinyl-tRNA-specific translation factor 174006..175850 Escherichia coli O104:H4 str. 2011C-3493 13698848 YP_006776916.1 CDS O3K_00900 NC_018658.1 176040 177191 D COG1454 Alcohol dehydrogenase, class IV; alcohol dehydrogenase 176040..177191 Escherichia coli O104:H4 str. 2011C-3493 13698849 YP_006776917.1 CDS O3K_00905 NC_018658.1 177356 178894 D COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 177356..178894 Escherichia coli O104:H4 str. 2011C-3493 13698850 YP_006776918.1 CDS O3K_00910 NC_018658.1 179113 179325 R hypothetical protein complement(179113..179325) Escherichia coli O104:H4 str. 2011C-3493 13698851 YP_006776919.1 CDS O3K_00915 NC_018658.1 179439 179762 D hypothetical protein 179439..179762 Escherichia coli O104:H4 str. 2011C-3493 13698852 YP_006776920.1 CDS O3K_00920 NC_018658.1 179768 180904 D COG1566 Multidrug resistance efflux pump; efflux pump membrane protein 179768..180904 Escherichia coli O104:H4 str. 2011C-3493 13698853 YP_006776921.1 CDS O3K_00925 NC_018658.1 180901 181875 R COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator complement(180901..181875) Escherichia coli O104:H4 str. 2011C-3493 13698854 YP_006776922.1 CDS O3K_00930 NC_018658.1 181999 182739 D COG3713 Outer membrane protein V; hypothetical protein 181999..182739 Escherichia coli O104:H4 str. 2011C-3493 13698855 YP_006776923.1 CDS sgbE NC_018658.1 183086 183781 R COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase complement(183086..183781) Escherichia coli O104:H4 str. 2011C-3493 13698856 YP_006776924.1 CDS O3K_00940 NC_018658.1 183775 184635 R COG3623 Putative L-xylulose-5-phosphate 3-epimerase; putative L-xylulose 5-phosphate 3-epimerase complement(183775..184635) Escherichia coli O104:H4 str. 2011C-3493 13698857 YP_006776925.1 CDS sgbH NC_018658.1 184628 185290 R COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-keto-L-gulonate-6-phosphate decarboxylase complement(184628..185290) Escherichia coli O104:H4 str. 2011C-3493 13698858 YP_006776926.1 CDS O3K_00950 NC_018658.1 185287 186783 R COG1070 Sugar (pentulose and hexulose) kinases; L-xylulose kinase complement(185287..186783) Escherichia coli O104:H4 str. 2011C-3493 13698859 YP_006776927.1 CDS O3K_00955 NC_018658.1 186787 187773 R COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component; transporter complement(186787..187773) Escherichia coli O104:H4 str. 2011C-3493 13698860 YP_006776928.1 CDS O3K_00960 NC_018658.1 187786 189063 R COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; L-dehydroascorbate transporter large permease subunit complement(187786..189063) Escherichia coli O104:H4 str. 2011C-3493 13698861 YP_006776929.1 CDS O3K_00965 NC_018658.1 189066 189539 R COG3090 TRAP-type C4-dicarboxylate transport system, small permease component; 2,3-diketo-L-gulonate TRAP transporter small permease complement(189066..189539) Escherichia coli O104:H4 str. 2011C-3493 13698862 YP_006776930.1 CDS O3K_00970 NC_018658.1 189657 190124 R COG2731 Beta-galactosidase, beta subunit; hypothetical protein complement(189657..190124) Escherichia coli O104:H4 str. 2011C-3493 13698863 YP_006776931.1 CDS O3K_00975 NC_018658.1 190136 191134 R COG2055 Malate/L-lactate dehydrogenases; 2,3-diketo-L-gulonate reductase complement(190136..191134) Escherichia coli O104:H4 str. 2011C-3493 13698864 YP_006776932.1 CDS O3K_00980 NC_018658.1 191335 192183 D COG1414 Transcriptional regulator; putative DNA-binding transcriptional repressor 191335..192183 Escherichia coli O104:H4 str. 2011C-3493 13698865 YP_006776933.1 CDS O3K_00985 NC_018658.1 192285 192758 D COG1142 Fe-S-cluster-containing hydrogenase components 2; 4Fe-4S binding protein 192285..192758 Escherichia coli O104:H4 str. 2011C-3493 13698866 YP_006776934.1 CDS O3K_00990 NC_018658.1 192778 192906 R hypothetical protein complement(192778..192906) Escherichia coli O104:H4 str. 2011C-3493 13698867 YP_006776935.1 CDS avtA NC_018658.1 192910 194163 R COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; valine--pyruvate transaminase complement(192910..194163) Escherichia coli O104:H4 str. 2011C-3493 13698868 YP_006776936.1 CDS O3K_01010 NC_018658.1 196690 197514 D COG2992 Uncharacterized FlgJ-related protein; hypothetical protein 196690..197514 Escherichia coli O104:H4 str. 2011C-3493 13698869 YP_006776937.1 CDS O3K_01015 NC_018658.1 197710 198888 R COG1609 Transcriptional regulators; DNA-binding transcriptional activator, xylose-binding protein complement(197710..198888) Escherichia coli O104:H4 str. 2011C-3493 13698870 YP_006776938.1 CDS O3K_01020 NC_018658.1 198966 200147 R COG4214 ABC-type xylose transport system, permease component; D-xylose ABC transporter permease complement(198966..200147) Escherichia coli O104:H4 str. 2011C-3493 13698871 YP_006776939.1 CDS O3K_01025 NC_018658.1 200125 201666 R COG1129 ABC-type sugar transport system, ATPase component; xylose transporter ATP-binding subunit complement(200125..201666) Escherichia coli O104:H4 str. 2011C-3493 13698872 YP_006776940.1 CDS xylF NC_018658.1 201744 202736 R COG4213 ABC-type xylose transport system, periplasmic component; D-xylose transporter subunit XylF complement(201744..202736) Escherichia coli O104:H4 str. 2011C-3493 13698873 YP_006776941.1 CDS O3K_01035 NC_018658.1 203102 204424 D COG2115 Xylose isomerase; xylose isomerase 203102..204424 Escherichia coli O104:H4 str. 2011C-3493 13698874 YP_006776942.1 CDS O3K_01040 NC_018658.1 204496 205950 D COG1070 Sugar (pentulose and hexulose) kinases; xylulokinase 204496..205950 Escherichia coli O104:H4 str. 2011C-3493 13698875 YP_006776943.1 CDS O3K_01045 NC_018658.1 206119 206460 D COG4682 Predicted membrane protein; hypothetical protein 206119..206460 Escherichia coli O104:H4 str. 2011C-3493 13698876 YP_006776944.1 CDS O3K_01050 NC_018658.1 206506 206943 D COG4682 Predicted membrane protein; hypothetical protein 206506..206943 Escherichia coli O104:H4 str. 2011C-3493 13698877 YP_006776945.1 CDS O3K_01055 NC_018658.1 206985 207980 R COG3274 Uncharacterized protein conserved in bacteria; hypothetical protein complement(206985..207980) Escherichia coli O104:H4 str. 2011C-3493 13698878 YP_006776946.1 CDS O3K_01060 NC_018658.1 208155 208454 D outer membrane lipoprotein 208155..208454 Escherichia coli O104:H4 str. 2011C-3493 13698879 YP_006776947.1 CDS glyQ NC_018658.1 208549 209460 D COG0752 Glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA synthetase subunit alpha 208549..209460 Escherichia coli O104:H4 str. 2011C-3493 13698880 YP_006776948.1 CDS glyS NC_018658.1 209470 211539 D COG0751 Glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase subunit beta 209470..211539 Escherichia coli O104:H4 str. 2011C-3493 13698881 YP_006776949.1 CDS O3K_01075 NC_018658.1 211805 212017 D small toxic polypeptide 211805..212017 Escherichia coli O104:H4 str. 2011C-3493 13698882 YP_006776950.1 CDS O3K_01080 NC_018658.1 212205 212417 R COG1278 Cold shock proteins; RNA chaperone/anti-terminator complement(212205..212417) Escherichia coli O104:H4 str. 2011C-3493 13698883 YP_006776951.1 CDS O3K_01085 NC_018658.1 212698 212988 R COG2944 Predicted transcriptional regulator; transcriptional regulator complement(212698..212988) Escherichia coli O104:H4 str. 2011C-3493 13698884 YP_006776952.1 CDS O3K_01090 NC_018658.1 213422 214132 D hypothetical protein 213422..214132 Escherichia coli O104:H4 str. 2011C-3493 13698885 YP_006776953.1 CDS O3K_01095 NC_018658.1 214182 215156 R COG1052 Lactate dehydrogenase and related dehydrogenases; bifunctional glyoxylate/hydroxypyruvate reductase B complement(214182..215156) Escherichia coli O104:H4 str. 2011C-3493 13698886 YP_006776954.1 CDS O3K_01100 NC_018658.1 215260 215919 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; putative outer membrane lipoprotein complement(215260..215919) Escherichia coli O104:H4 str. 2011C-3493 13698887 YP_006776955.1 CDS O3K_01105 NC_018658.1 216072 218405 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; biotin sulfoxide reductase 216072..218405 Escherichia coli O104:H4 str. 2011C-3493 13698888 YP_006776956.1 CDS O3K_01110 NC_018658.1 218374 218814 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase complement(218374..218814) Escherichia coli O104:H4 str. 2011C-3493 13698889 YP_006776957.1 CDS O3K_01115 NC_018658.1 218811 219374 R COG2818 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase complement(218811..219374) Escherichia coli O104:H4 str. 2011C-3493 13698890 YP_006776958.1 CDS O3K_01120 NC_018658.1 219532 220230 D hypothetical protein 219532..220230 Escherichia coli O104:H4 str. 2011C-3493 13698891 YP_006776959.1 CDS O3K_01125 NC_018658.1 220459 221661 D COG0477 Permeases of the major facilitator superfamily; transporter 220459..221661 Escherichia coli O104:H4 str. 2011C-3493 13698892 YP_006776960.1 CDS O3K_01130 NC_018658.1 221985 222509 D COG3539 P pilus assembly protein, pilin FimA; long polar fimbrial protein LpfA 221985..222509 Escherichia coli O104:H4 str. 2011C-3493 13698893 YP_006776961.1 CDS O3K_01135 NC_018658.1 222593 223279 D COG3121 P pilus assembly protein, chaperone PapD; long polar fimbrial chaperone LpfB 222593..223279 Escherichia coli O104:H4 str. 2011C-3493 13698894 YP_006776962.1 CDS O3K_01140 NC_018658.1 223303 225834 D COG3188 P pilus assembly protein, porin PapC; long polar fimbrial outer membrane usher protein LpfC 223303..225834 Escherichia coli O104:H4 str. 2011C-3493 13698895 YP_006776963.1 CDS O3K_01145 NC_018658.1 225845 226900 D long polar fimbrial protein LpfD 225845..226900 Escherichia coli O104:H4 str. 2011C-3493 13698896 YP_006776964.1 CDS O3K_01150 NC_018658.1 226906 227430 D COG3539 P pilus assembly protein, pilin FimA; long polar fimbrial protein LpfE 226906..227430 Escherichia coli O104:H4 str. 2011C-3493 13698897 YP_006776965.1 CDS O3K_01155 NC_018658.1 227683 229374 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; phosphoethanolamine transferase 227683..229374 Escherichia coli O104:H4 str. 2011C-3493 13698898 YP_006776966.1 CDS O3K_01160 NC_018658.1 230286 231893 D COG0747 ABC-type dipeptide transport system, periplasmic component; dipeptide transport protein 230286..231893 Escherichia coli O104:H4 str. 2011C-3493 13698900 YP_006776967.1 CDS O3K_01165 NC_018658.1 232044 233063 D COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide transporter permease DppB 232044..233063 Escherichia coli O104:H4 str. 2011C-3493 13698901 YP_006776968.1 CDS O3K_01170 NC_018658.1 233073 233975 D COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide transporter 233073..233975 Escherichia coli O104:H4 str. 2011C-3493 13698902 YP_006776969.1 CDS dppD NC_018658.1 233986 234969 D COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; dipeptide transporter ATP-binding subunit 233986..234969 Escherichia coli O104:H4 str. 2011C-3493 13698903 YP_006776970.1 CDS dppF NC_018658.1 234966 235970 D COG4608 ABC-type oligopeptide transport system, ATPase component; dipeptide transporter ATP-binding subunit 234966..235970 Escherichia coli O104:H4 str. 2011C-3493 13698904 YP_006776971.1 CDS O3K_01185 NC_018658.1 236000 237271 R COG0814 Amino acid permeases; transporter complement(236000..237271) Escherichia coli O104:H4 str. 2011C-3493 13698905 YP_006776972.1 CDS O3K_01190 NC_018658.1 238229 238336 D toxic polypeptide, small 238229..238336 Escherichia coli O104:H4 str. 2011C-3493 13698906 YP_006776973.1 CDS O3K_01195 NC_018658.1 238712 238819 D toxic polypeptide, small 238712..238819 Escherichia coli O104:H4 str. 2011C-3493 13698907 YP_006776974.1 CDS O3K_01200 NC_018658.1 238906 240585 R hypothetical protein complement(238906..240585) Escherichia coli O104:H4 str. 2011C-3493 13698908 YP_006776975.1 CDS O3K_01205 NC_018658.1 240582 240773 R hypothetical protein complement(240582..240773) Escherichia coli O104:H4 str. 2011C-3493 13698909 YP_006776976.1 CDS O3K_01220 NC_018658.1 242615 242803 D hypothetical protein 242615..242803 Escherichia coli O104:H4 str. 2011C-3493 13698910 YP_006776977.1 CDS O3K_01225 NC_018658.1 242815 243567 D COG1192 ATPases involved in chromosome partitioning; cell division protein 242815..243567 Escherichia coli O104:H4 str. 2011C-3493 13698911 YP_006776978.1 CDS bcsA NC_018658.1 243564 246182 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; cellulose synthase catalytic subunit 243564..246182 Escherichia coli O104:H4 str. 2011C-3493 13698912 YP_006776979.1 CDS O3K_01235 NC_018658.1 246193 248532 D cellulose synthase regulator protein 246193..248532 Escherichia coli O104:H4 str. 2011C-3493 13698913 YP_006776980.1 CDS O3K_01240 NC_018658.1 248539 249645 D COG3405 Endoglucanase Y; endo-1,4-D-glucanase 248539..249645 Escherichia coli O104:H4 str. 2011C-3493 13698914 YP_006776981.1 CDS O3K_01245 NC_018658.1 249627 253100 D COG0457 FOG: TPR repeat; cellulose synthase subunit BcsC 249627..253100 Escherichia coli O104:H4 str. 2011C-3493 13698915 YP_006776982.1 CDS O3K_01250 NC_018658.1 253215 255170 D COG2199 FOG: GGDEF domain; putative diguanylate cyclase 253215..255170 Escherichia coli O104:H4 str. 2011C-3493 13698916 YP_006776983.1 CDS O3K_01255 NC_018658.1 255353 256639 D COG1301 Na+/H+-dicarboxylate symporters; C4-dicarboxylate transporter DctA 255353..256639 Escherichia coli O104:H4 str. 2011C-3493 13698917 YP_006776984.1 CDS O3K_01260 NC_018658.1 256860 258356 D COG0612 Predicted Zn-dependent peptidases; putative zinc-dependent peptidase 256860..258356 Escherichia coli O104:H4 str. 2011C-3493 13698918 YP_006776985.1 CDS O3K_01265 NC_018658.1 258452 259381 R COG0524 Sugar kinases, ribokinase family; ketodeoxygluconokinase complement(258452..259381) Escherichia coli O104:H4 str. 2011C-3493 13698919 YP_006776986.1 CDS O3K_01270 NC_018658.1 259613 260380 D COG2200 FOG: EAL domain; cyclic-di-GMP phosphodiesterase 259613..260380 Escherichia coli O104:H4 str. 2011C-3493 13698920 YP_006776987.1 CDS O3K_01275 NC_018658.1 260450 262510 D COG2982 Uncharacterized protein involved in outer membrane biogenesis; outer membrane biogenesis protein 260450..262510 Escherichia coli O104:H4 str. 2011C-3493 13698921 YP_006776988.1 CDS O3K_01280 NC_018658.1 262744 264066 R COG0477 Permeases of the major facilitator superfamily; inner membrane metabolite transport protein yhjE complement(262744..264066) Escherichia coli O104:H4 str. 2011C-3493 13698922 YP_006776989.1 CDS O3K_01285 NC_018658.1 264477 265490 R COG1295 Predicted membrane protein; ribonuclease complement(264477..265490) Escherichia coli O104:H4 str. 2011C-3493 13698923 YP_006776990.1 CDS O3K_01290 NC_018658.1 265539 266510 R COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator complement(265539..266510) Escherichia coli O104:H4 str. 2011C-3493 13698924 YP_006776991.1 CDS O3K_01295 NC_018658.1 266958 267560 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; HTH-type transcriptional regulator yhjB 266958..267560 Escherichia coli O104:H4 str. 2011C-3493 13698925 YP_006776992.1 CDS treF NC_018658.1 267611 269260 R COG1626 Neutral trehalase; trehalase complement(267611..269260) Escherichia coli O104:H4 str. 2011C-3493 13698926 YP_006776993.1 CDS O3K_01305 NC_018658.1 269665 271062 D COG1858 Cytochrome c peroxidase; cytochrome C peroxidase 269665..271062 Escherichia coli O104:H4 str. 2011C-3493 13698927 YP_006776994.1 CDS O3K_01310 NC_018658.1 271273 272097 D COG0076 Glutamate decarboxylase and related PLP-dependent proteins; glutamate decarboxylase 271273..272097 Escherichia coli O104:H4 str. 2011C-3493 13698928 YP_006776995.1 CDS O3K_01315 NC_018658.1 272069 272671 D COG0076 Glutamate decarboxylase and related PLP-dependent proteins; glutamate decarboxylase 272069..272671 Escherichia coli O104:H4 str. 2011C-3493 13698929 YP_006776996.1 CDS O3K_01320 NC_018658.1 273041 273865 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator GadX 273041..273865 Escherichia coli O104:H4 str. 2011C-3493 13698930 YP_006776997.1 CDS O3K_01325 NC_018658.1 274233 274961 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator GadW 274233..274961 Escherichia coli O104:H4 str. 2011C-3493 13698931 YP_006776998.1 CDS O3K_01330 NC_018658.1 275324 278437 R COG0841 Cation/multidrug efflux pump; multidrug transporter MdtF, RpoS-dependent complement(275324..278437) Escherichia coli O104:H4 str. 2011C-3493 13698932 YP_006776999.1 CDS O3K_01335 NC_018658.1 278462 279619 R COG0845 Membrane-fusion protein; multidrug efflux system protein MdtE complement(278462..279619) Escherichia coli O104:H4 str. 2011C-3493 13698933 YP_006777000.1 CDS O3K_01340 NC_018658.1 279525 279641 D hypothetical protein 279525..279641 Escherichia coli O104:H4 str. 2011C-3493 13698934 YP_006777001.1 CDS O3K_01345 NC_018658.1 279679 279957 D hypothetical protein 279679..279957 Escherichia coli O104:H4 str. 2011C-3493 13698935 YP_006777002.1 CDS O3K_01350 NC_018658.1 279958 280485 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator complement(279958..280485) Escherichia coli O104:H4 str. 2011C-3493 13698936 YP_006777003.1 CDS O3K_01355 NC_018658.1 281284 281856 R COG3247 Uncharacterized conserved protein; acid-resistance membrane protein complement(281284..281856) Escherichia coli O104:H4 str. 2011C-3493 13698937 YP_006777004.1 CDS O3K_01360 NC_018658.1 282111 282443 D acid-resistance protein 282111..282443 Escherichia coli O104:H4 str. 2011C-3493 13698938 YP_006777005.1 CDS hdeB NC_018658.1 282547 282885 D acid-resistance protein 282547..282885 Escherichia coli O104:H4 str. 2011C-3493 13698939 YP_006777006.1 CDS O3K_01370 NC_018658.1 282949 283596 D COG1285 Uncharacterized membrane protein; putative Mg(2+) transport ATPase 282949..283596 Escherichia coli O104:H4 str. 2011C-3493 13698940 YP_006777007.1 CDS O3K_01375 NC_018658.1 283638 284168 R COG0055 F0F1-type ATP synthase, beta subunit; DNA-binding transcriptional regulator complement(283638..284168) Escherichia coli O104:H4 str. 2011C-3493 13698941 YP_006777008.1 CDS O3K_01380 NC_018658.1 284324 284890 R COG3065 Starvation-inducible outer membrane lipoprotein; outer membrane lipoprotein complement(284324..284890) Escherichia coli O104:H4 str. 2011C-3493 13698942 YP_006777009.1 CDS O3K_01385 NC_018658.1 285214 286359 R COG1518 Uncharacterized protein predicted to be involved in DNA repair; hypothetical protein complement(285214..286359) Escherichia coli O104:H4 str. 2011C-3493 13698943 YP_006777010.1 CDS O3K_01390 NC_018658.1 286939 287952 R COG0701 Predicted permeases; hypothetical protein complement(286939..287952) Escherichia coli O104:H4 str. 2011C-3493 13698944 YP_006777011.1 CDS O3K_01395 NC_018658.1 288059 288355 D COG0640 Predicted transcriptional regulators; hypothetical protein 288059..288355 Escherichia coli O104:H4 str. 2011C-3493 13698945 YP_006777012.1 CDS O3K_01400 NC_018658.1 288489 288914 R COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase complement(288489..288914) Escherichia coli O104:H4 str. 2011C-3493 13698946 YP_006777013.1 CDS O3K_01405 NC_018658.1 288927 290216 R COG1055 Na+/H+ antiporter NhaD and related arsenite permeases; arsenical pump membrane protein complement(288927..290216) Escherichia coli O104:H4 str. 2011C-3493 13698947 YP_006777014.1 CDS O3K_01410 NC_018658.1 290270 290623 R COG0640 Predicted transcriptional regulators; DNA-binding transcriptional repressor ArsR complement(290270..290623) Escherichia coli O104:H4 str. 2011C-3493 13698948 YP_006777015.1 CDS O3K_01415 NC_018658.1 291297 291446 D hypothetical protein 291297..291446 Escherichia coli O104:H4 str. 2011C-3493 13698949 YP_006777016.1 CDS O3K_01420 NC_018658.1 291500 292852 R COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; glutathione reductase complement(291500..292852) Escherichia coli O104:H4 str. 2011C-3493 13698950 YP_006777017.1 CDS O3K_01425 NC_018658.1 292924 293766 R COG2961 Protein involved in catabolism of external DNA; putative DNA processing protein complement(292924..293766) Escherichia coli O104:H4 str. 2011C-3493 13698951 YP_006777018.1 CDS O3K_01430 NC_018658.1 293969 296011 D COG0339 Zn-dependent oligopeptidases; oligopeptidase A 293969..296011 Escherichia coli O104:H4 str. 2011C-3493 13698952 YP_006777019.1 CDS O3K_01435 NC_018658.1 296019 296771 D COG0500 SAM-dependent methyltransferases; methyltransferase 296019..296771 Escherichia coli O104:H4 str. 2011C-3493 13698953 YP_006777020.1 CDS O3K_01440 NC_018658.1 296820 298289 R COG3104 Dipeptide/tripeptide permease; dipeptide/tripeptide permease B complement(296820..298289) Escherichia coli O104:H4 str. 2011C-3493 13698954 YP_006777021.1 CDS O3K_01445 NC_018658.1 298607 299041 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress global response regulator UspA complement(298607..299041) Escherichia coli O104:H4 str. 2011C-3493 13698955 YP_006777022.1 CDS O3K_01450 NC_018658.1 299432 299767 D universal stress protein UspB 299432..299767 Escherichia coli O104:H4 str. 2011C-3493 13698956 YP_006777023.1 CDS O3K_01455 NC_018658.1 299838 301337 R COG0306 Phosphate/sulphate permeases; Low-affinity inorganic phosphate transporter 1 complement(299838..301337) Escherichia coli O104:H4 str. 2011C-3493 13698957 YP_006777024.1 CDS O3K_01460 NC_018658.1 301569 302771 D COG2081 Predicted flavoproteins; pyridine nucleotide-disulfide oxidoreductase 301569..302771 Escherichia coli O104:H4 str. 2011C-3493 13698958 YP_006777025.1 CDS O3K_01465 NC_018658.1 302914 303756 D Tn7-like transposase TnsA 302914..303756 Escherichia coli O104:H4 str. 2011C-3493 13698959 YP_006777026.1 CDS O3K_01470 NC_018658.1 303743 305866 D COG2801 Transposase and inactivated derivatives; Tn7-like transposition protein TnsB 303743..305866 Escherichia coli O104:H4 str. 2011C-3493 13698960 YP_006777027.1 CDS O3K_01475 NC_018658.1 305866 307314 D COG1132 ABC-type multidrug transport system, ATPase and permease components; Tn7-like transposition protein TnsC 305866..307314 Escherichia coli O104:H4 str. 2011C-3493 13698961 YP_006777028.1 CDS O3K_01480 NC_018658.1 307346 308911 D TnsD 307346..308911 Escherichia coli O104:H4 str. 2011C-3493 13698962 YP_006777029.1 CDS O3K_01485 NC_018658.1 308923 309849 D hypothetical protein 308923..309849 Escherichia coli O104:H4 str. 2011C-3493 13698963 YP_006777030.1 CDS O3K_01490 NC_018658.1 310202 310501 D COG1396 Predicted transcriptional regulators; transcriptional regulator 310202..310501 Escherichia coli O104:H4 str. 2011C-3493 13698964 YP_006777031.1 CDS O3K_01495 NC_018658.1 311065 312891 D COG3593 Predicted ATP-dependent endonuclease of the OLD family; hypothetical protein 311065..312891 Escherichia coli O104:H4 str. 2011C-3493 13698965 YP_006777032.1 CDS O3K_01500 NC_018658.1 313060 313410 R COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein complement(313060..313410) Escherichia coli O104:H4 str. 2011C-3493 13698966 YP_006777033.1 CDS O3K_01505 NC_018658.1 313558 314106 R silver-binding protein SilE complement(313558..314106) Escherichia coli O104:H4 str. 2011C-3493 13698967 YP_006777034.1 CDS O3K_01510 NC_018658.1 314234 315715 R COG0642 Signal transduction histidine kinase; sensor kinase CusS complement(314234..315715) Escherichia coli O104:H4 str. 2011C-3493 13698968 YP_006777035.1 CDS O3K_01515 NC_018658.1 315708 316388 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator CusR complement(315708..316388) Escherichia coli O104:H4 str. 2011C-3493 13698969 YP_006777036.1 CDS O3K_01520 NC_018658.1 316578 317963 D COG1538 Outer membrane protein; copper/silver efflux system outer membrane protein CusC 316578..317963 Escherichia coli O104:H4 str. 2011C-3493 13698970 YP_006777037.1 CDS O3K_01525 NC_018658.1 317991 318344 D COG5569 Uncharacterized conserved protein; copper-binding protein 317991..318344 Escherichia coli O104:H4 str. 2011C-3493 13698971 YP_006777038.1 CDS O3K_01530 NC_018658.1 318458 319750 D COG0845 Membrane-fusion protein; copper/silver efflux system membrane fusion protein CusB 318458..319750 Escherichia coli O104:H4 str. 2011C-3493 13698972 YP_006777039.1 CDS O3K_01535 NC_018658.1 319761 322907 D COG3696 Putative silver efflux pump; Cu(I)/Ag(I) efflux system membrane protein CusA 319761..322907 Escherichia coli O104:H4 str. 2011C-3493 13698973 YP_006777040.1 CDS O3K_01540 NC_018658.1 322994 323434 D COG3019 Predicted metal-binding protein; hypothetical protein 322994..323434 Escherichia coli O104:H4 str. 2011C-3493 13698974 YP_006777041.1 CDS O3K_01545 NC_018658.1 323561 326008 D COG2217 Cation transport ATPase; cation-transporting P-type ATPase 323561..326008 Escherichia coli O104:H4 str. 2011C-3493 13698975 YP_006777042.1 CDS O3K_01550 NC_018658.1 326049 326246 D hypothetical protein 326049..326246 Escherichia coli O104:H4 str. 2011C-3493 13698976 YP_006777043.1 CDS O3K_01555 NC_018658.1 326280 327017 R COG0739 Membrane proteins related to metalloendopeptidases; peptidase complement(326280..327017) Escherichia coli O104:H4 str. 2011C-3493 13698977 YP_006777044.1 CDS O3K_01560 NC_018658.1 327110 327196 D hypothetical protein 327110..327196 Escherichia coli O104:H4 str. 2011C-3493 13698978 YP_006777045.1 CDS O3K_01565 NC_018658.1 327306 327755 R copper resistant protein PcoE complement(327306..327755) Escherichia coli O104:H4 str. 2011C-3493 13698979 YP_006777046.1 CDS O3K_01570 NC_018658.1 327990 329807 D COG2132 Putative multicopper oxidases; copper resistant protein PcoA 327990..329807 Escherichia coli O104:H4 str. 2011C-3493 13698980 YP_006777047.1 CDS O3K_01575 NC_018658.1 329804 330703 D COG3667 Uncharacterized protein involved in copper resistance; copper resistance protein B 329804..330703 Escherichia coli O104:H4 str. 2011C-3493 13698981 YP_006777048.1 CDS O3K_01580 NC_018658.1 330743 331123 D COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; copper resistant protein PcoC 330743..331123 Escherichia coli O104:H4 str. 2011C-3493 13698982 YP_006777049.1 CDS O3K_01585 NC_018658.1 331128 332057 D COG1276 Putative copper export protein; copper resistance protein D 331128..332057 Escherichia coli O104:H4 str. 2011C-3493 13698983 YP_006777050.1 CDS O3K_01590 NC_018658.1 332112 332792 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator PcoR 332112..332792 Escherichia coli O104:H4 str. 2011C-3493 13698984 YP_006777051.1 CDS O3K_01595 NC_018658.1 332789 334189 D COG0642 Signal transduction histidine kinase; sensor protein pcoS 332789..334189 Escherichia coli O104:H4 str. 2011C-3493 13698985 YP_006777052.1 CDS O3K_01600 NC_018658.1 334407 334841 D copper-binding protein 334407..334841 Escherichia coli O104:H4 str. 2011C-3493 13698986 YP_006777053.1 CDS O3K_01605 NC_018658.1 335501 336553 R hypothetical protein complement(335501..336553) Escherichia coli O104:H4 str. 2011C-3493 13698987 YP_006777054.1 CDS O3K_01610 NC_018658.1 336938 338023 D hypothetical protein 336938..338023 Escherichia coli O104:H4 str. 2011C-3493 13698988 YP_006777055.1 CDS O3K_01615 NC_018658.1 338191 338562 D hypothetical protein 338191..338562 Escherichia coli O104:H4 str. 2011C-3493 13698989 YP_006777056.1 CDS O3K_01630 NC_018658.1 340811 341878 D COG0845 Membrane-fusion protein; HlyD family secretion protein 340811..341878 Escherichia coli O104:H4 str. 2011C-3493 13698990 YP_006777057.1 CDS O3K_01635 NC_018658.1 341875 344610 D COG1131 ABC-type multidrug transport system, ATPase component; ribosome-associated ATPase/membrane protein 341875..344610 Escherichia coli O104:H4 str. 2011C-3493 13698991 YP_006777058.1 CDS O3K_01640 NC_018658.1 344610 345734 D COG0842 ABC-type multidrug transport system, permease component; transporter subunit 344610..345734 Escherichia coli O104:H4 str. 2011C-3493 13698992 YP_006777059.1 CDS O3K_01645 NC_018658.1 346065 346424 D COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters; HicB family protein 346065..346424 Escherichia coli O104:H4 str. 2011C-3493 13698993 YP_006777060.1 CDS O3K_01650 NC_018658.1 346544 346945 R COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; nickel responsive regulator complement(346544..346945) Escherichia coli O104:H4 str. 2011C-3493 13698994 YP_006777061.1 CDS nikE NC_018658.1 346951 347757 R COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; nickel transporter ATP-binding protein NikE complement(346951..347757) Escherichia coli O104:H4 str. 2011C-3493 13698995 YP_006777062.1 CDS nikD NC_018658.1 347754 348518 R COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; nickel transporter ATP-binding protein NikD complement(347754..348518) Escherichia coli O104:H4 str. 2011C-3493 13698996 YP_006777063.1 CDS nikC NC_018658.1 348518 349351 R COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; nickel transporter permease NikC complement(348518..349351) Escherichia coli O104:H4 str. 2011C-3493 13698997 YP_006777064.1 CDS O3K_01670 NC_018658.1 349348 350292 R COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; nickel transporter permease NikB complement(349348..350292) Escherichia coli O104:H4 str. 2011C-3493 13698998 YP_006777065.1 CDS O3K_01675 NC_018658.1 350292 351866 R COG0747 ABC-type dipeptide transport system, periplasmic component; periplasmic binding protein for nickel NikA complement(350292..351866) Escherichia coli O104:H4 str. 2011C-3493 13698999 YP_006777066.1 CDS O3K_01680 NC_018658.1 351977 352564 R COG2091 Phosphopantetheinyl transferase; holo-(acyl carrier protein) synthase 2 complement(351977..352564) Escherichia coli O104:H4 str. 2011C-3493 13699000 YP_006777067.1 CDS O3K_01685 NC_018658.1 352619 353668 R COG0628 Predicted permease; inner membrane protein complement(352619..353668) Escherichia coli O104:H4 str. 2011C-3493 13699001 YP_006777068.1 CDS O3K_01690 NC_018658.1 353800 355017 D COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily transporter 353800..355017 Escherichia coli O104:H4 str. 2011C-3493 13699002 YP_006777069.1 CDS O3K_01695 NC_018658.1 355021 355578 R hypothetical protein complement(355021..355578) Escherichia coli O104:H4 str. 2011C-3493 13699003 YP_006777070.1 CDS O3K_01700 NC_018658.1 355651 356316 R COG1738 Uncharacterized conserved protein; hypothetical protein complement(355651..356316) Escherichia coli O104:H4 str. 2011C-3493 13699004 YP_006777071.1 CDS O3K_01705 NC_018658.1 356537 356782 D COG0425 Predicted redox protein, regulator of disulfide bond formation; sulfur transfer protein SirA 356537..356782 Escherichia coli O104:H4 str. 2011C-3493 13699005 YP_006777072.1 CDS zntA NC_018658.1 356884 359082 R COG2217 Cation transport ATPase; zinc/cadmium/mercury/lead-transporting ATPase complement(356884..359082) Escherichia coli O104:H4 str. 2011C-3493 13699006 YP_006777073.1 CDS O3K_01715 NC_018658.1 359156 359782 R COG3714 Predicted membrane protein; hypothetical protein complement(359156..359782) Escherichia coli O104:H4 str. 2011C-3493 13699007 YP_006777074.1 CDS O3K_01720 NC_018658.1 359923 360282 D hypothetical protein 359923..360282 Escherichia coli O104:H4 str. 2011C-3493 13699008 YP_006777075.1 CDS O3K_01725 NC_018658.1 360285 360554 R COG3776 Predicted membrane protein; hypothetical protein complement(360285..360554) Escherichia coli O104:H4 str. 2011C-3493 13699009 YP_006777076.1 CDS rsmD NC_018658.1 360544 361140 R COG0742 N6-adenine-specific methylase; 16S rRNA m(2)G966-methyltransferase complement(360544..361140) Escherichia coli O104:H4 str. 2011C-3493 13699010 YP_006777077.1 CDS O3K_01735 NC_018658.1 361290 362783 D COG0552 Signal recognition particle GTPase; signal recognition particle-docking protein FtsY 361290..362783 Escherichia coli O104:H4 str. 2011C-3493 13699011 YP_006777078.1 CDS O3K_01740 NC_018658.1 362786 363454 D COG2884 Predicted ATPase involved in cell division; cell division protein FtsE 362786..363454 Escherichia coli O104:H4 str. 2011C-3493 13699012 YP_006777079.1 CDS ftsX NC_018658.1 363447 364505 D COG2177 Cell division protein; cell division ABC transporter subunit FtsX 363447..364505 Escherichia coli O104:H4 str. 2011C-3493 13699013 YP_006777080.1 CDS O3K_01750 NC_018658.1 364750 365604 D COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase factor sigma-32 364750..365604 Escherichia coli O104:H4 str. 2011C-3493 13699014 YP_006777081.1 CDS O3K_01755 NC_018658.1 365875 366978 D COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; leucine ABC transporter subunit substrate-binding protein LivK 365875..366978 Escherichia coli O104:H4 str. 2011C-3493 13699015 YP_006777082.1 CDS O3K_01760 NC_018658.1 367034 367168 R hypothetical protein complement(367034..367168) Escherichia coli O104:H4 str. 2011C-3493 13699016 YP_006777083.1 CDS O3K_01765 NC_018658.1 367177 367560 R hypothetical protein complement(367177..367560) Escherichia coli O104:H4 str. 2011C-3493 13699017 YP_006777084.1 CDS O3K_01770 NC_018658.1 367984 369093 D COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; leucine ABC transporter subunit substrate-binding protein LivK 367984..369093 Escherichia coli O104:H4 str. 2011C-3493 13699018 YP_006777085.1 CDS O3K_01775 NC_018658.1 369141 370067 D COG0559 Branched-chain amino acid ABC-type transport system, permease components; branched-chain amino acid transporter permease LivH 369141..370067 Escherichia coli O104:H4 str. 2011C-3493 13699019 YP_006777086.1 CDS livM NC_018658.1 370064 371341 D COG4177 ABC-type branched-chain amino acid transport system, permease component; leucine/isoleucine/valine transporter permease subunit 370064..371341 Escherichia coli O104:H4 str. 2011C-3493 13699020 YP_006777087.1 CDS livG NC_018658.1 371338 372105 D COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; leucine/isoleucine/valine transporter ATP-binding subunit 371338..372105 Escherichia coli O104:H4 str. 2011C-3493 13699021 YP_006777088.1 CDS livF NC_018658.1 372119 372820 D COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; leucine/isoleucine/valine transporter ATP-binding subunit 372119..372820 Escherichia coli O104:H4 str. 2011C-3493 13699022 YP_006777089.1 CDS O3K_01795 NC_018658.1 372856 372984 D hypothetical protein 372856..372984 Escherichia coli O104:H4 str. 2011C-3493 13699023 YP_006777090.1 CDS O3K_01800 NC_018658.1 373216 374532 D COG1653 ABC-type sugar transport system, periplasmic component; glycerol-3-phosphate transporter periplasmic binding protein 373216..374532 Escherichia coli O104:H4 str. 2011C-3493 13699024 YP_006777091.1 CDS O3K_01805 NC_018658.1 374630 375517 D COG1175 ABC-type sugar transport systems, permease components; glycerol-3-phosphate transporter permease 374630..375517 Escherichia coli O104:H4 str. 2011C-3493 13699025 YP_006777092.1 CDS O3K_01810 NC_018658.1 375514 376359 D COG0395 ABC-type sugar transport system, permease component; glycerol-3-phosphate transporter membrane protein 375514..376359 Escherichia coli O104:H4 str. 2011C-3493 13699026 YP_006777093.1 CDS ugpC NC_018658.1 376361 377431 D COG3839 ABC-type sugar transport systems, ATPase components; glycerol-3-phosphate transporter ATP-binding subunit 376361..377431 Escherichia coli O104:H4 str. 2011C-3493 13699027 YP_006777094.1 CDS ugpQ NC_018658.1 377428 378171 D COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphodiester phosphodiesterase 377428..378171 Escherichia coli O104:H4 str. 2011C-3493 13699028 YP_006777095.1 CDS O3K_01825 NC_018658.1 378158 378598 R hypothetical protein complement(378158..378598) Escherichia coli O104:H4 str. 2011C-3493 13699029 YP_006777096.1 CDS ggt NC_018658.1 378718 380460 D COG0405 Gamma-glutamyltransferase; gamma-glutamyltranspeptidase 378718..380460 Escherichia coli O104:H4 str. 2011C-3493 13699030 YP_006777097.1 CDS O3K_01835 NC_018658.1 380498 380782 R hypothetical protein complement(380498..380782) Escherichia coli O104:H4 str. 2011C-3493 13699031 YP_006777098.1 CDS O3K_01840 NC_018658.1 381232 381726 R hypothetical protein complement(381232..381726) Escherichia coli O104:H4 str. 2011C-3493 13699032 YP_006777099.1 CDS O3K_01845 NC_018658.1 381723 382901 R COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein complement(381723..382901) Escherichia coli O104:H4 str. 2011C-3493 13699033 YP_006777100.1 CDS O3K_01850 NC_018658.1 383138 383626 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative acetyltransferase YhhY complement(383138..383626) Escherichia coli O104:H4 str. 2011C-3493 13699034 YP_006777101.1 CDS O3K_01855 NC_018658.1 383958 384995 D COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 383958..384995 Escherichia coli O104:H4 str. 2011C-3493 13699035 YP_006777102.1 CDS O3K_01860 NC_018658.1 385118 385813 D COG1741 Pirin-related protein; protein yhhW 385118..385813 Escherichia coli O104:H4 str. 2011C-3493 13699036 YP_006777103.1 CDS O3K_01865 NC_018658.1 386037 387032 D COG1609 Transcriptional regulators; gluconate operon transcriptional regulator 386037..387032 Escherichia coli O104:H4 str. 2011C-3493 13699037 YP_006777104.1 CDS gntK NC_018658.1 387171 387698 D COG3265 Gluconate kinase; gluconate kinase 387171..387698 Escherichia coli O104:H4 str. 2011C-3493 13699038 YP_006777105.1 CDS O3K_01875 NC_018658.1 387702 389042 D COG2610 H+/gluconate symporter and related permeases; low affinity gluconate transporter 387702..389042 Escherichia coli O104:H4 str. 2011C-3493 13699039 YP_006777106.1 CDS O3K_01880 NC_018658.1 389099 389692 R COG2095 Multiple antibiotic transporter; putative antibiotic transporter complement(389099..389692) Escherichia coli O104:H4 str. 2011C-3493 13699040 YP_006777107.1 CDS O3K_01885 NC_018658.1 389885 390988 D COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 389885..390988 Escherichia coli O104:H4 str. 2011C-3493 13699041 YP_006777108.1 CDS O3K_01890 NC_018658.1 391261 393447 D COG0296 1,4-alpha-glucan branching enzyme; glycogen branching protein 391261..393447 Escherichia coli O104:H4 str. 2011C-3493 13699042 YP_006777109.1 CDS O3K_01895 NC_018658.1 393444 395417 D COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen debranching protein 393444..395417 Escherichia coli O104:H4 str. 2011C-3493 13699043 YP_006777110.1 CDS glgC NC_018658.1 395435 396730 D COG0448 ADP-glucose pyrophosphorylase; glucose-1-phosphate adenylyltransferase 395435..396730 Escherichia coli O104:H4 str. 2011C-3493 13699044 YP_006777111.1 CDS glgA NC_018658.1 396730 398163 D COG0297 Glycogen synthase; glycogen synthase 396730..398163 Escherichia coli O104:H4 str. 2011C-3493 13699045 YP_006777112.1 CDS O3K_01910 NC_018658.1 398182 400629 D COG0058 Glucan phosphorylase; glycogen phosphorylase 398182..400629 Escherichia coli O104:H4 str. 2011C-3493 13699046 YP_006777113.1 CDS O3K_01915 NC_018658.1 400745 402262 D COG0226 ABC-type phosphate transport system, periplasmic component; phosphate transport system substrate-binding protein 400745..402262 Escherichia coli O104:H4 str. 2011C-3493 13699047 YP_006777114.1 CDS O3K_01920 NC_018658.1 402278 402988 D hypothetical protein 402278..402988 Escherichia coli O104:H4 str. 2011C-3493 13699048 YP_006777115.1 CDS O3K_01925 NC_018658.1 402991 403758 D hypothetical protein 402991..403758 Escherichia coli O104:H4 str. 2011C-3493 13699049 YP_006777116.1 CDS O3K_01930 NC_018658.1 403761 404366 D hypothetical protein 403761..404366 Escherichia coli O104:H4 str. 2011C-3493 13699050 YP_006777117.1 CDS glpD NC_018658.1 404418 405923 R COG0578 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase complement(404418..405923) Escherichia coli O104:H4 str. 2011C-3493 13699051 YP_006777118.1 CDS glpE NC_018658.1 406113 406439 D COG0607 Rhodanese-related sulfurtransferase; thiosulfate sulfurtransferase 406113..406439 Escherichia coli O104:H4 str. 2011C-3493 13699052 YP_006777119.1 CDS O3K_01945 NC_018658.1 406484 407314 D COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); intramembrane serine protease GlpG 406484..407314 Escherichia coli O104:H4 str. 2011C-3493 13699053 YP_006777120.1 CDS O3K_01950 NC_018658.1 407331 408089 D COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor GlpR 407331..408089 Escherichia coli O104:H4 str. 2011C-3493 13699054 YP_006777121.1 CDS O3K_01955 NC_018658.1 408071 409669 R COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain; sigma 54-dependent transcriptional regulator of rtcBA expression complement(408071..409669) Escherichia coli O104:H4 str. 2011C-3493 13699055 YP_006777122.1 CDS O3K_01960 NC_018658.1 409858 411084 D COG1690 Uncharacterized conserved protein; hypothetical protein 409858..411084 Escherichia coli O104:H4 str. 2011C-3493 13699056 YP_006777123.1 CDS O3K_01965 NC_018658.1 411088 412104 D COG0430 RNA 3'-terminal phosphate cyclase; RNA 3'-terminal-phosphate cyclase 411088..412104 Escherichia coli O104:H4 str. 2011C-3493 13699057 YP_006777124.1 CDS O3K_01970 NC_018658.1 412147 414852 R COG2909 ATP-dependent transcriptional regulator; transcriptional regulator MalT complement(412147..414852) Escherichia coli O104:H4 str. 2011C-3493 13699058 YP_006777125.1 CDS O3K_01975 NC_018658.1 415464 417857 D COG0058 Glucan phosphorylase; maltodextrin phosphorylase 415464..417857 Escherichia coli O104:H4 str. 2011C-3493 13699059 YP_006777126.1 CDS malQ NC_018658.1 417867 419951 D COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 417867..419951 Escherichia coli O104:H4 str. 2011C-3493 13699060 YP_006777127.1 CDS O3K_01985 NC_018658.1 419996 421312 R COG2610 H+/gluconate symporter and related permeases; high-affinity gluconate transporter complement(419996..421312) Escherichia coli O104:H4 str. 2011C-3493 13699061 YP_006777128.1 CDS O3K_01990 NC_018658.1 421673 422248 R COG0316 Uncharacterized conserved protein; Fe/S biogenesis protein NfuA complement(421673..422248) Escherichia coli O104:H4 str. 2011C-3493 13699062 YP_006777129.1 CDS O3K_01995 NC_018658.1 422307 422990 R COG1040 Predicted amidophosphoribosyltransferases; DNA utilization protein GntX complement(422307..422990) Escherichia coli O104:H4 str. 2011C-3493 13699063 YP_006777130.1 CDS O3K_02000 NC_018658.1 423028 423798 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); carboxylesterase BioH 423028..423798 Escherichia coli O104:H4 str. 2011C-3493 13699064 YP_006777131.1 CDS O3K_02005 NC_018658.1 423827 424705 R transposase complement(423827..424705) Escherichia coli O104:H4 str. 2011C-3493 13699065 YP_006777132.1 CDS O3K_02010 NC_018658.1 424908 425144 R ferrous iron transport protein FeoC complement(424908..425144) Escherichia coli O104:H4 str. 2011C-3493 13699066 YP_006777133.1 CDS feoB NC_018658.1 425144 427465 R COG0370 Fe2+ transport system protein B; ferrous iron transport protein B complement(425144..427465) Escherichia coli O104:H4 str. 2011C-3493 13699067 YP_006777134.1 CDS feoA NC_018658.1 427482 427709 R COG1918 Fe2+ transport system protein A; ferrous iron transport protein A complement(427482..427709) Escherichia coli O104:H4 str. 2011C-3493 13699068 YP_006777135.1 CDS O3K_02025 NC_018658.1 428147 430468 R COG2183 Transcriptional accessory protein; putative transcriptional accessory protein complement(428147..430468) Escherichia coli O104:H4 str. 2011C-3493 13699069 YP_006777136.1 CDS greB NC_018658.1 430565 431041 R COG0782 Transcription elongation factor; transcription elongation factor GreB complement(430565..431041) Escherichia coli O104:H4 str. 2011C-3493 13699070 YP_006777137.1 CDS ompR NC_018658.1 431269 431988 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; osmolarity response regulator 431269..431988 Escherichia coli O104:H4 str. 2011C-3493 13699071 YP_006777138.1 CDS envZ NC_018658.1 431985 433337 D COG0642 Signal transduction histidine kinase; osmolarity sensor protein 431985..433337 Escherichia coli O104:H4 str. 2011C-3493 13699072 YP_006777139.1 CDS O3K_02045 NC_018658.1 433367 433663 R COG2944 Predicted transcriptional regulator; HTH-type transcriptional regulator yiaG complement(433367..433663) Escherichia coli O104:H4 str. 2011C-3493 13699073 YP_006777140.1 CDS O3K_02050 NC_018658.1 433722 434039 R COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; hypothetical protein complement(433722..434039) Escherichia coli O104:H4 str. 2011C-3493 13699074 YP_006777141.1 CDS O3K_02055 NC_018658.1 434156 435778 R COG1866 Phosphoenolpyruvate carboxykinase (ATP); phosphoenolpyruvate carboxykinase complement(434156..435778) Escherichia coli O104:H4 str. 2011C-3493 13699075 YP_006777142.1 CDS O3K_02060 NC_018658.1 436157 437881 D inner membrane protein 436157..437881 Escherichia coli O104:H4 str. 2011C-3493 13699076 YP_006777143.1 CDS hslO NC_018658.1 438016 438894 R COG1281 Disulfide bond chaperones of the HSP33 family; Hsp33-like chaperonin complement(438016..438894) Escherichia coli O104:H4 str. 2011C-3493 13699077 YP_006777144.1 CDS O3K_02070 NC_018658.1 438919 439320 R COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); ribosome-associated heat shock protein Hsp15 complement(438919..439320) Escherichia coli O104:H4 str. 2011C-3493 13699078 YP_006777145.1 CDS O3K_02075 NC_018658.1 439331 439999 R COG1011 Predicted hydrolase (HAD superfamily); GMP/IMP nucleotidase complement(439331..439999) Escherichia coli O104:H4 str. 2011C-3493 13699079 YP_006777146.1 CDS O3K_02080 NC_018658.1 440064 442199 R intracellular growth attenuator protein complement(440064..442199) Escherichia coli O104:H4 str. 2011C-3493 13699080 YP_006777147.1 CDS nudE NC_018658.1 442519 443079 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; adenosine nucleotide hydrolase NudE 442519..443079 Escherichia coli O104:H4 str. 2011C-3493 13699081 YP_006777148.1 CDS mrcA NC_018658.1 443247 445799 R COG5009 Membrane carboxypeptidase/penicillin-binding protein; penicillin-binding protein 1a complement(443247..445799) Escherichia coli O104:H4 str. 2011C-3493 13699082 YP_006777149.1 CDS O3K_02095 NC_018658.1 445919 446698 D putative pilus assembly protein 445919..446698 Escherichia coli O104:H4 str. 2011C-3493 13699083 YP_006777150.1 CDS O3K_02100 NC_018658.1 446698 447237 D putative fimbrial assembly protein 446698..447237 Escherichia coli O104:H4 str. 2011C-3493 13699084 YP_006777151.1 CDS O3K_02105 NC_018658.1 447221 447661 D hypothetical protein 447221..447661 Escherichia coli O104:H4 str. 2011C-3493 13699085 YP_006777152.1 CDS O3K_02110 NC_018658.1 447651 448055 D hypothetical protein 447651..448055 Escherichia coli O104:H4 str. 2011C-3493 13699086 YP_006777153.1 CDS hofQ NC_018658.1 447967 449205 D COG4796 Type II secretory pathway, component HofQ; outer membrane porin HofQ 447967..449205 Escherichia coli O104:H4 str. 2011C-3493 13699087 YP_006777154.1 CDS aroK NC_018658.1 449606 450127 D COG0703 Shikimate kinase; shikimate kinase I 449606..450127 Escherichia coli O104:H4 str. 2011C-3493 13699088 YP_006777155.1 CDS aroB NC_018658.1 450184 451272 D COG0337 3-dehydroquinate synthetase; 3-dehydroquinate synthase 450184..451272 Escherichia coli O104:H4 str. 2011C-3493 13699089 YP_006777156.1 CDS O3K_02130 NC_018658.1 451364 452650 D COG3266 Uncharacterized protein conserved in bacteria; cell division protein DamX 451364..452650 Escherichia coli O104:H4 str. 2011C-3493 13699090 YP_006777157.1 CDS O3K_02135 NC_018658.1 452757 453593 D COG0338 Site-specific DNA methylase; DNA adenine methylase 452757..453593 Escherichia coli O104:H4 str. 2011C-3493 13699091 YP_006777158.1 CDS O3K_02140 NC_018658.1 453611 454288 D COG0036 Pentose-5-phosphate-3-epimerase; ribulose-phosphate 3-epimerase 453611..454288 Escherichia coli O104:H4 str. 2011C-3493 13699092 YP_006777159.1 CDS O3K_02145 NC_018658.1 454281 455039 D COG0546 Predicted phosphatases; phosphoglycolate phosphatase 454281..455039 Escherichia coli O104:H4 str. 2011C-3493 13699093 YP_006777160.1 CDS O3K_02150 NC_018658.1 455032 456036 D COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 455032..456036 Escherichia coli O104:H4 str. 2011C-3493 13699094 YP_006777161.1 CDS O3K_02155 NC_018658.1 456305 457210 D hypothetical protein 456305..457210 Escherichia coli O104:H4 str. 2011C-3493 13699095 YP_006777162.1 CDS O3K_02160 NC_018658.1 457227 457589 D hypothetical protein 457227..457589 Escherichia coli O104:H4 str. 2011C-3493 13699096 YP_006777163.1 CDS O3K_02165 NC_018658.1 457673 458836 D COG3457 Predicted amino acid racemase; putative amino acid racemase 457673..458836 Escherichia coli O104:H4 str. 2011C-3493 13699097 YP_006777164.1 CDS O3K_02170 NC_018658.1 458836 460062 D COG1015 Phosphopentomutase; putative mutase 458836..460062 Escherichia coli O104:H4 str. 2011C-3493 13699098 YP_006777165.1 CDS O3K_02175 NC_018658.1 460059 460937 D COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold; hydrolase 460059..460937 Escherichia coli O104:H4 str. 2011C-3493 13699099 YP_006777166.1 CDS O3K_02180 NC_018658.1 460948 461301 D COG0698 Ribose 5-phosphate isomerase RpiB; hypothetical protein 460948..461301 Escherichia coli O104:H4 str. 2011C-3493 13699100 YP_006777167.1 CDS O3K_02185 NC_018658.1 461313 462617 D inner membrane protein 461313..462617 Escherichia coli O104:H4 str. 2011C-3493 13699101 YP_006777168.1 CDS O3K_02190 NC_018658.1 462629 463714 D hypothetical protein 462629..463714 Escherichia coli O104:H4 str. 2011C-3493 13699102 YP_006777169.1 CDS O3K_02195 NC_018658.1 463866 464597 R COG2188 Transcriptional regulators; DNA-binding transcriptional regulator FrlR complement(463866..464597) Escherichia coli O104:H4 str. 2011C-3493 13699103 YP_006777170.1 CDS O3K_02200 NC_018658.1 464697 465482 R COG0524 Sugar kinases, ribokinase family; fructoselysine 6-kinase complement(464697..465482) Escherichia coli O104:H4 str. 2011C-3493 13699104 YP_006777171.1 CDS O3K_02205 NC_018658.1 465479 466309 R COG1082 Sugar phosphate isomerases/epimerases; fructoselysine 3-epimerase complement(465479..466309) Escherichia coli O104:H4 str. 2011C-3493 13699105 YP_006777172.1 CDS frlB NC_018658.1 466359 467381 R COG2222 Predicted phosphosugar isomerases; fructoselysine-6-P-deglycase complement(466359..467381) Escherichia coli O104:H4 str. 2011C-3493 13699106 YP_006777173.1 CDS frlA NC_018658.1 467402 468739 R COG0531 Amino acid transporters; putative fructoselysine transporter complement(467402..468739) Escherichia coli O104:H4 str. 2011C-3493 13699107 YP_006777174.1 CDS O3K_02220 NC_018658.1 469034 469201 R lipoprotein complement(469034..469201) Escherichia coli O104:H4 str. 2011C-3493 13699108 YP_006777175.1 CDS cysG NC_018658.1 469448 470821 R COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); siroheme synthase complement(469448..470821) Escherichia coli O104:H4 str. 2011C-3493 13699109 YP_006777176.1 CDS O3K_02230 NC_018658.1 470840 471646 R COG2116 Formate/nitrite family of transporters; nitrite transporter NirC complement(470840..471646) Escherichia coli O104:H4 str. 2011C-3493 13699110 YP_006777177.1 CDS nirD NC_018658.1 471773 472099 R COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; nitrite reductase small subunit complement(471773..472099) Escherichia coli O104:H4 str. 2011C-3493 13699111 YP_006777178.1 CDS O3K_02240 NC_018658.1 472096 474639 R COG1251 NAD(P)H-nitrite reductase; nitrite reductase subunit NirD complement(472096..474639) Escherichia coli O104:H4 str. 2011C-3493 13699112 YP_006777179.1 CDS O3K_02245 NC_018658.1 474901 476082 R COG0477 Permeases of the major facilitator superfamily; transporter complement(474901..476082) Escherichia coli O104:H4 str. 2011C-3493 13699113 YP_006777180.1 CDS O3K_02250 NC_018658.1 476353 476925 D COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase A 476353..476925 Escherichia coli O104:H4 str. 2011C-3493 13699114 YP_006777181.1 CDS O3K_02255 NC_018658.1 477030 477197 D hypothetical protein 477030..477197 Escherichia coli O104:H4 str. 2011C-3493 13699115 YP_006777182.1 CDS O3K_02260 NC_018658.1 477187 477789 D COG2184 Protein involved in cell division; cell filamentation protein Fic 477187..477789 Escherichia coli O104:H4 str. 2011C-3493 13699116 YP_006777183.1 CDS O3K_02265 NC_018658.1 477821 478384 D COG0512 Anthranilate/para-aminobenzoate synthases component II; para-aminobenzoate synthase component II 477821..478384 Escherichia coli O104:H4 str. 2011C-3493 13699117 YP_006777184.1 CDS argD NC_018658.1 478470 479690 D COG4992 Ornithine/acetylornithine aminotransferase; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 478470..479690 Escherichia coli O104:H4 str. 2011C-3493 13699118 YP_006777185.1 CDS O3K_02275 NC_018658.1 479757 481847 R COG1289 Predicted membrane protein; hypothetical protein complement(479757..481847) Escherichia coli O104:H4 str. 2011C-3493 13699119 YP_006777186.1 CDS O3K_02280 NC_018658.1 481898 482530 R COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; DNA-binding transcriptional dual regulator Crp complement(481898..482530) Escherichia coli O104:H4 str. 2011C-3493 13699120 YP_006777187.1 CDS O3K_02285 NC_018658.1 482832 483236 D COG1765 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 482832..483236 Escherichia coli O104:H4 str. 2011C-3493 13699121 YP_006777188.1 CDS O3K_02290 NC_018658.1 483291 484160 R COG3954 Phosphoribulokinase; phosphoribulokinase complement(483291..484160) Escherichia coli O104:H4 str. 2011C-3493 13699122 YP_006777189.1 CDS O3K_02295 NC_018658.1 484214 484432 R COG3089 Uncharacterized protein conserved in bacteria; hypothetical protein complement(484214..484432) Escherichia coli O104:H4 str. 2011C-3493 13699123 YP_006777190.1 CDS O3K_02300 NC_018658.1 484426 485448 R COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold; hydrolase complement(484426..485448) Escherichia coli O104:H4 str. 2011C-3493 13699124 YP_006777191.1 CDS O3K_02305 NC_018658.1 485448 487361 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein complement(485448..487361) Escherichia coli O104:H4 str. 2011C-3493 13699125 YP_006777192.1 CDS O3K_02310 NC_018658.1 487492 488043 D COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); glutathione-regulated potassium-efflux system ancillary protein KefG 487492..488043 Escherichia coli O104:H4 str. 2011C-3493 13699126 YP_006777193.1 CDS O3K_02315 NC_018658.1 488043 489848 D COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefB 488043..489848 Escherichia coli O104:H4 str. 2011C-3493 13699127 YP_006777194.1 CDS O3K_02320 NC_018658.1 489858 490058 D COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain; hypothetical protein 489858..490058 Escherichia coli O104:H4 str. 2011C-3493 13699128 YP_006777195.1 CDS O3K_02325 NC_018658.1 490153 490743 D COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; FKBP-type peptidyl-prolyl cis-trans isomerase 490153..490743 Escherichia coli O104:H4 str. 2011C-3493 13699129 YP_006777196.1 CDS O3K_02330 NC_018658.1 490792 491010 R COG2900 Uncharacterized protein conserved in bacteria; phi X174 lysis protein complement(490792..491010) Escherichia coli O104:H4 str. 2011C-3493 13699130 YP_006777197.1 CDS O3K_02335 NC_018658.1 491231 492043 D COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; FKBP-type peptidyl-prolyl cis-trans isomerase 491231..492043 Escherichia coli O104:H4 str. 2011C-3493 13699131 YP_006777198.1 CDS O3K_02340 NC_018658.1 492210 492932 D COG2964 Uncharacterized protein conserved in bacteria; DNA-binding transcriptional regulator 492210..492932 Escherichia coli O104:H4 str. 2011C-3493 13699132 YP_006777199.1 CDS O3K_02345 NC_018658.1 492932 493318 D COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction; sulfur transfer complex subunit TusD 492932..493318 Escherichia coli O104:H4 str. 2011C-3493 13699133 YP_006777200.1 CDS O3K_02350 NC_018658.1 493318 493677 D COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur; sulfur relay protein TusC 493318..493677 Escherichia coli O104:H4 str. 2011C-3493 13699134 YP_006777201.1 CDS O3K_02355 NC_018658.1 493685 493972 D COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur; sulfur transfer complex subunit TusB 493685..493972 Escherichia coli O104:H4 str. 2011C-3493 13699135 YP_006777202.1 CDS rpsL NC_018658.1 494098 494472 D COG0048 Ribosomal protein S12; 30S ribosomal protein S12 494098..494472 Escherichia coli O104:H4 str. 2011C-3493 13699136 YP_006777203.1 CDS O3K_02365 NC_018658.1 494569 495039 D COG0049 Ribosomal protein S7; 30S ribosomal protein S7 494569..495039 Escherichia coli O104:H4 str. 2011C-3493 13699137 YP_006777204.1 CDS O3K_02370 NC_018658.1 495136 497250 D COG0480 Translation elongation factors (GTPases); elongation factor G 495136..497250 Escherichia coli O104:H4 str. 2011C-3493 13699138 YP_006777205.1 CDS O3K_02375 NC_018658.1 497321 498505 D COG0050 GTPases - translation elongation factors; elongation factor Tu 497321..498505 Escherichia coli O104:H4 str. 2011C-3493 13699139 YP_006777206.1 CDS O3K_02380 NC_018658.1 498688 498882 D COG2906 Bacterioferritin-associated ferredoxin; bacterioferritin-associated ferredoxin 498688..498882 Escherichia coli O104:H4 str. 2011C-3493 13699140 YP_006777207.1 CDS O3K_02385 NC_018658.1 498955 499431 D COG2193 Bacterioferritin (cytochrome b1); bacterioferritin 498955..499431 Escherichia coli O104:H4 str. 2011C-3493 13699141 YP_006777208.1 CDS O3K_02390 NC_018658.1 499428 499895 R COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; bifunctional prepilin peptidase HopD complement(499428..499895) Escherichia coli O104:H4 str. 2011C-3493 13699142 YP_006777209.1 CDS rpsJ NC_018658.1 500274 500585 D COG0051 Ribosomal protein S10; 30S ribosomal protein S10 500274..500585 Escherichia coli O104:H4 str. 2011C-3493 13699143 YP_006777210.1 CDS rplC NC_018658.1 500618 501247 D COG0087 Ribosomal protein L3; 50S ribosomal protein L3 500618..501247 Escherichia coli O104:H4 str. 2011C-3493 13699144 YP_006777211.1 CDS rplD NC_018658.1 501258 501863 D COG0088 Ribosomal protein L4; 50S ribosomal protein L4 501258..501863 Escherichia coli O104:H4 str. 2011C-3493 13699145 YP_006777212.1 CDS rplW NC_018658.1 501860 502162 D COG0089 Ribosomal protein L23; 50S ribosomal protein L23 501860..502162 Escherichia coli O104:H4 str. 2011C-3493 13699146 YP_006777213.1 CDS rplB NC_018658.1 502180 503001 D COG0090 Ribosomal protein L2; 50S ribosomal protein L2 502180..503001 Escherichia coli O104:H4 str. 2011C-3493 13699147 YP_006777214.1 CDS rpsS NC_018658.1 503018 503296 D COG0185 Ribosomal protein S19; 30S ribosomal protein S19 503018..503296 Escherichia coli O104:H4 str. 2011C-3493 13699148 YP_006777215.1 CDS rplV NC_018658.1 503311 503643 D COG0091 Ribosomal protein L22; 50S ribosomal protein L22 503311..503643 Escherichia coli O104:H4 str. 2011C-3493 13699149 YP_006777216.1 CDS rpsC NC_018658.1 503661 504362 D COG0092 Ribosomal protein S3; 30S ribosomal protein S3 503661..504362 Escherichia coli O104:H4 str. 2011C-3493 13699150 YP_006777217.1 CDS rplP NC_018658.1 504375 504785 D COG0197 Ribosomal protein L16/L10E; 50S ribosomal protein L16 504375..504785 Escherichia coli O104:H4 str. 2011C-3493 13699151 YP_006777218.1 CDS O3K_02440 NC_018658.1 504785 504976 D COG0255 Ribosomal protein L29; 50S ribosomal protein L29 504785..504976 Escherichia coli O104:H4 str. 2011C-3493 13699152 YP_006777219.1 CDS rpsQ NC_018658.1 504976 505230 D COG0186 Ribosomal protein S17; 30S ribosomal protein S17 504976..505230 Escherichia coli O104:H4 str. 2011C-3493 13699153 YP_006777220.1 CDS rplN NC_018658.1 505395 505766 D COG0093 Ribosomal protein L14; 50S ribosomal protein L14 505395..505766 Escherichia coli O104:H4 str. 2011C-3493 13699154 YP_006777221.1 CDS rplX NC_018658.1 505777 506091 D COG0198 Ribosomal protein L24; 50S ribosomal protein L24 505777..506091 Escherichia coli O104:H4 str. 2011C-3493 13699155 YP_006777222.1 CDS rplE NC_018658.1 506106 506645 D COG0094 Ribosomal protein L5; 50S ribosomal protein L5 506106..506645 Escherichia coli O104:H4 str. 2011C-3493 13699156 YP_006777223.1 CDS rpsN NC_018658.1 506660 506965 D COG0199 Ribosomal protein S14; 30S ribosomal protein S14 506660..506965 Escherichia coli O104:H4 str. 2011C-3493 13699157 YP_006777224.1 CDS rpsH NC_018658.1 506999 507391 D COG0096 Ribosomal protein S8; 30S ribosomal protein S8 506999..507391 Escherichia coli O104:H4 str. 2011C-3493 13699158 YP_006777225.1 CDS rplF NC_018658.1 507404 507937 D COG0097 Ribosomal protein L6P/L9E; 50S ribosomal protein L6 507404..507937 Escherichia coli O104:H4 str. 2011C-3493 13699159 YP_006777226.1 CDS rplR NC_018658.1 507947 508300 D COG0256 Ribosomal protein L18; 50S ribosomal protein L18 507947..508300 Escherichia coli O104:H4 str. 2011C-3493 13699160 YP_006777227.1 CDS rpsE NC_018658.1 508315 508818 D COG0098 Ribosomal protein S5; 30S ribosomal protein S5 508315..508818 Escherichia coli O104:H4 str. 2011C-3493 13699161 YP_006777228.1 CDS rpmD NC_018658.1 508822 509001 D COG1841 Ribosomal protein L30/L7E; 50S ribosomal protein L30 508822..509001 Escherichia coli O104:H4 str. 2011C-3493 13699162 YP_006777229.1 CDS rplO NC_018658.1 509005 509439 D COG0200 Ribosomal protein L15; 50S ribosomal protein L15 509005..509439 Escherichia coli O104:H4 str. 2011C-3493 13699163 YP_006777230.1 CDS secY NC_018658.1 509447 510778 D COG0201 Preprotein translocase subunit SecY; preprotein translocase subunit SecY 509447..510778 Escherichia coli O104:H4 str. 2011C-3493 13699164 YP_006777231.1 CDS rpmJ NC_018658.1 510810 510926 D COG0257 Ribosomal protein L36; 50S ribosomal protein L36 510810..510926 Escherichia coli O104:H4 str. 2011C-3493 13699165 YP_006777232.1 CDS rpsM NC_018658.1 511073 511429 D COG0099 Ribosomal protein S13; 30S ribosomal protein S13 511073..511429 Escherichia coli O104:H4 str. 2011C-3493 13699166 YP_006777233.1 CDS O3K_02515 NC_018658.1 511446 511835 D COG0100 Ribosomal protein S11; 30S ribosomal protein S11 511446..511835 Escherichia coli O104:H4 str. 2011C-3493 13699167 YP_006777234.1 CDS rpsD NC_018658.1 511869 512489 D COG0522 Ribosomal protein S4 and related proteins; 30S ribosomal protein S4 511869..512489 Escherichia coli O104:H4 str. 2011C-3493 13699168 YP_006777235.1 CDS O3K_02525 NC_018658.1 512515 513504 D COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-directed RNA polymerase subunit alpha 512515..513504 Escherichia coli O104:H4 str. 2011C-3493 13699169 YP_006777236.1 CDS rplQ NC_018658.1 513545 513928 D COG0203 Ribosomal protein L17; 50S ribosomal protein L17 513545..513928 Escherichia coli O104:H4 str. 2011C-3493 13699170 YP_006777237.1 CDS O3K_02535 NC_018658.1 514035 514403 D hypothetical protein 514035..514403 Escherichia coli O104:H4 str. 2011C-3493 13699171 YP_006777238.1 CDS zntR NC_018658.1 514414 514839 D COG0789 Predicted transcriptional regulators; zinc-responsive transcriptional regulator 514414..514839 Escherichia coli O104:H4 str. 2011C-3493 13699172 YP_006777239.1 CDS O3K_02545 NC_018658.1 514895 515113 D COG3036 Uncharacterized protein conserved in bacteria; hypothetical protein 514895..515113 Escherichia coli O104:H4 str. 2011C-3493 13699173 YP_006777240.1 CDS mscL NC_018658.1 515110 515520 R COG1970 Large-conductance mechanosensitive channel; large conductance mechanosensitive channel protein complement(515110..515520) Escherichia coli O104:H4 str. 2011C-3493 13699174 YP_006777241.1 CDS trkA NC_018658.1 515650 517026 R COG0569 K+ transport systems, NAD-binding component; potassium transporter peripheral membrane protein complement(515650..517026) Escherichia coli O104:H4 str. 2011C-3493 13699175 YP_006777242.1 CDS O3K_02560 NC_018658.1 517048 518337 R COG0144 tRNA and rRNA cytosine-C5-methylases; 16S rRNA methyltransferase B complement(517048..518337) Escherichia coli O104:H4 str. 2011C-3493 13699176 YP_006777243.1 CDS fmt NC_018658.1 518383 519330 R COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase complement(518383..519330) Escherichia coli O104:H4 str. 2011C-3493 13699177 YP_006777244.1 CDS def NC_018658.1 519345 519854 R COG0242 N-formylmethionyl-tRNA deformylase; peptide deformylase complement(519345..519854) Escherichia coli O104:H4 str. 2011C-3493 13699178 YP_006777245.1 CDS O3K_02575 NC_018658.1 519984 521108 D COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 519984..521108 Escherichia coli O104:H4 str. 2011C-3493 13699179 YP_006777246.1 CDS O3K_02580 NC_018658.1 521080 521553 D COG2922 Uncharacterized protein conserved in bacteria; hypothetical protein 521080..521553 Escherichia coli O104:H4 str. 2011C-3493 13699180 YP_006777247.1 CDS O3K_02585 NC_018658.1 521582 522124 D COG0551 Zn-finger domain associated with topoisomerase type I; putative DNA topoisomerase 521582..522124 Escherichia coli O104:H4 str. 2011C-3493 13699181 YP_006777248.1 CDS O3K_02590 NC_018658.1 522129 522701 D COG0009 Putative translation factor (SUA5); tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein 522129..522701 Escherichia coli O104:H4 str. 2011C-3493 13699182 YP_006777249.1 CDS aroE NC_018658.1 522706 523524 D COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 522706..523524 Escherichia coli O104:H4 str. 2011C-3493 13699183 YP_006777250.1 CDS O3K_02600 NC_018658.1 523521 523778 D hypothetical protein 523521..523778 Escherichia coli O104:H4 str. 2011C-3493 13699184 YP_006777251.1 CDS O3K_02605 NC_018658.1 523754 524308 R COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; hypothetical protein complement(523754..524308) Escherichia coli O104:H4 str. 2011C-3493 13699185 YP_006777252.1 CDS O3K_02610 NC_018658.1 530360 531118 R COG1126 ABC-type polar amino acid transport system, ATPase component; phosphate ABC transporter ATP-binding protein complement(530360..531118) Escherichia coli O104:H4 str. 2011C-3493 13699193 YP_006777253.1 CDS O3K_02615 NC_018658.1 531126 532229 R COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(531126..532229) Escherichia coli O104:H4 str. 2011C-3493 13699194 YP_006777254.1 CDS O3K_02620 NC_018658.1 532239 533420 R COG4597 ABC-type amino acid transport system, permease component; transport system permease complement(532239..533420) Escherichia coli O104:H4 str. 2011C-3493 13699195 YP_006777255.1 CDS O3K_02625 NC_018658.1 533488 534513 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein complement(533488..534513) Escherichia coli O104:H4 str. 2011C-3493 13699196 YP_006777256.1 CDS O3K_02630 NC_018658.1 534944 535165 R hypothetical protein complement(534944..535165) Escherichia coli O104:H4 str. 2011C-3493 13699197 YP_006777257.1 CDS O3K_02635 NC_018658.1 535418 538522 R COG0841 Cation/multidrug efflux pump; acriflavine resistance protein complement(535418..538522) Escherichia coli O104:H4 str. 2011C-3493 13699198 YP_006777258.1 CDS O3K_02640 NC_018658.1 538534 539691 R COG0845 Membrane-fusion protein; hypothetical protein complement(538534..539691) Escherichia coli O104:H4 str. 2011C-3493 13699199 YP_006777259.1 CDS O3K_02645 NC_018658.1 540090 540752 D COG1309 Transcriptional regulator; DNA-binding transcriptional regulator EnvR 540090..540752 Escherichia coli O104:H4 str. 2011C-3493 13699200 YP_006777260.1 CDS O3K_02650 NC_018658.1 540755 540934 R hypothetical protein complement(540755..540934) Escherichia coli O104:H4 str. 2011C-3493 13699201 YP_006777261.1 CDS O3K_02655 NC_018658.1 541018 541902 R COG0863 DNA modification methylase; methyltransferase complement(541018..541902) Escherichia coli O104:H4 str. 2011C-3493 13699202 YP_006777262.1 CDS fis NC_018658.1 541988 542284 R COG2901 Factor for inversion stimulation Fis, transcriptional activator; global DNA-binding transcriptional dual regulator Fis complement(541988..542284) Escherichia coli O104:H4 str. 2011C-3493 13699203 YP_006777263.1 CDS O3K_02665 NC_018658.1 542310 543275 R COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase B complement(542310..543275) Escherichia coli O104:H4 str. 2011C-3493 13699204 YP_006777264.1 CDS prmA NC_018658.1 543604 544485 R COG2264 Ribosomal protein L11 methylase; 50S ribosomal protein L11 methyltransferase complement(543604..544485) Escherichia coli O104:H4 str. 2011C-3493 13699205 YP_006777265.1 CDS panF NC_018658.1 544497 545948 R COG4145 Na+/panthothenate symporter; sodium/panthothenate symporter complement(544497..545948) Escherichia coli O104:H4 str. 2011C-3493 13699206 YP_006777266.1 CDS O3K_02680 NC_018658.1 545938 546180 R COG3924 Predicted membrane protein; hypothetical protein complement(545938..546180) Escherichia coli O104:H4 str. 2011C-3493 13699207 YP_006777267.1 CDS O3K_02685 NC_018658.1 546289 547638 R COG0439 Biotin carboxylase; acetyl-CoA carboxylase biotin carboxylase subunit complement(546289..547638) Escherichia coli O104:H4 str. 2011C-3493 13699208 YP_006777268.1 CDS O3K_02690 NC_018658.1 547649 548119 R COG0511 Biotin carboxyl carrier protein; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(547649..548119) Escherichia coli O104:H4 str. 2011C-3493 13699209 YP_006777269.1 CDS O3K_02695 NC_018658.1 548524 548688 R COG2717 Predicted membrane protein; hypothetical protein complement(548524..548688) Escherichia coli O104:H4 str. 2011C-3493 13699210 YP_006777270.1 CDS O3K_02700 NC_018658.1 549097 550071 R COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; quinone oxidoreductase complement(549097..550071) Escherichia coli O104:H4 str. 2011C-3493 13699211 YP_006777271.1 CDS O3K_02705 NC_018658.1 550223 552163 D COG2199 FOG: GGDEF domain; regulatory protein CsrD 550223..552163 Escherichia coli O104:H4 str. 2011C-3493 13699212 YP_006777272.1 CDS O3K_02710 NC_018658.1 552468 553511 D COG1077 Actin-like ATPase involved in cell morphogenesis; rod shape-determining protein MreB 552468..553511 Escherichia coli O104:H4 str. 2011C-3493 13699213 YP_006777273.1 CDS O3K_02715 NC_018658.1 553577 554680 D COG1792 Cell shape-determining protein; rod shape-determining protein MreC 553577..554680 Escherichia coli O104:H4 str. 2011C-3493 13699214 YP_006777274.1 CDS O3K_02720 NC_018658.1 554565 554696 D hypothetical protein 554565..554696 Escherichia coli O104:H4 str. 2011C-3493 13699215 YP_006777275.1 CDS O3K_02725 NC_018658.1 554680 555168 D COG2891 Cell shape-determining protein; rod shape-determining protein MreD 554680..555168 Escherichia coli O104:H4 str. 2011C-3493 13699216 YP_006777276.1 CDS O3K_02730 NC_018658.1 555177 555770 D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; Maf-like protein 555177..555770 Escherichia coli O104:H4 str. 2011C-3493 13699217 YP_006777277.1 CDS O3K_02735 NC_018658.1 555760 557229 D COG1530 Ribonucleases G and E; ribonuclease G 555760..557229 Escherichia coli O104:H4 str. 2011C-3493 13699218 YP_006777278.1 CDS O3K_02740 NC_018658.1 557297 561097 D COG3164 Predicted membrane protein; hypothetical protein 557297..561097 Escherichia coli O104:H4 str. 2011C-3493 13699219 YP_006777279.1 CDS tldD NC_018658.1 561253 562698 D COG0312 Predicted Zn-dependent proteases and their inactivated homologs; protease TldD 561253..562698 Escherichia coli O104:H4 str. 2011C-3493 13699220 YP_006777280.1 CDS O3K_02750 NC_018658.1 562826 563755 R COG0583 Transcriptional regulator; transcriptional regulator complement(562826..563755) Escherichia coli O104:H4 str. 2011C-3493 13699221 YP_006777281.1 CDS O3K_02755 NC_018658.1 563938 564141 D efflux system membrane protein 563938..564141 Escherichia coli O104:H4 str. 2011C-3493 13699222 YP_006777282.1 CDS O3K_02760 NC_018658.1 564149 565081 D COG1566 Multidrug resistance efflux pump; p-hydroxybenzoic acid efflux subunit AaeA 564149..565081 Escherichia coli O104:H4 str. 2011C-3493 13699223 YP_006777283.1 CDS O3K_02765 NC_018658.1 565087 567054 D COG1289 Predicted membrane protein; p-hydroxybenzoic acid efflux subunit AaeB 565087..567054 Escherichia coli O104:H4 str. 2011C-3493 13699224 YP_006777284.1 CDS O3K_02770 NC_018658.1 567146 567418 D COG2732 Barstar, RNAse (barnase) inhibitor; putative barnase inhibitor 567146..567418 Escherichia coli O104:H4 str. 2011C-3493 13699225 YP_006777285.1 CDS O3K_02775 NC_018658.1 567474 567737 R hypothetical protein complement(567474..567737) Escherichia coli O104:H4 str. 2011C-3493 13699226 YP_006777286.1 CDS O3K_02780 NC_018658.1 568102 568572 R COG1438 Arginine repressor; arginine repressor complement(568102..568572) Escherichia coli O104:H4 str. 2011C-3493 13699227 YP_006777287.1 CDS O3K_02785 NC_018658.1 569007 569945 D COG0039 Malate/lactate dehydrogenases; malate dehydrogenase 569007..569945 Escherichia coli O104:H4 str. 2011C-3493 13699228 YP_006777288.1 CDS O3K_02790 NC_018658.1 570008 571075 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease complement(570008..571075) Escherichia coli O104:H4 str. 2011C-3493 13699229 YP_006777289.1 CDS O3K_02795 NC_018658.1 571165 572532 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease complement(571165..572532) Escherichia coli O104:H4 str. 2011C-3493 13699230 YP_006777290.1 CDS O3K_02800 NC_018658.1 572686 573084 R COG3105 Uncharacterized protein conserved in bacteria; hypothetical protein complement(572686..573084) Escherichia coli O104:H4 str. 2011C-3493 13699231 YP_006777291.1 CDS O3K_02805 NC_018658.1 573278 574405 D nucleoside triphosphate hydrolase; COG1485 Predicted ATPase; ATPase 573278..574405 Escherichia coli O104:H4 str. 2011C-3493 13699232 YP_006777292.1 CDS rplM NC_018658.1 574624 575052 D COG0102 Ribosomal protein L13; 50S ribosomal protein L13 574624..575052 Escherichia coli O104:H4 str. 2011C-3493 13699233 YP_006777293.1 CDS rpsI NC_018658.1 575068 575460 D COG0103 Ribosomal protein S9; 30S ribosomal protein S9 575068..575460 Escherichia coli O104:H4 str. 2011C-3493 13699234 YP_006777294.1 CDS sspA NC_018658.1 575855 576493 D COG0625 Glutathione S-transferase; stringent starvation protein A 575855..576493 Escherichia coli O104:H4 str. 2011C-3493 13699235 YP_006777295.1 CDS O3K_02825 NC_018658.1 576499 576996 D COG2969 Stringent starvation protein B; ClpXP protease specificity-enhancing factor 576499..576996 Escherichia coli O104:H4 str. 2011C-3493 13699236 YP_006777296.1 CDS O3K_02830 NC_018658.1 577039 578406 R COG3069 C4-dicarboxylate transporter; putative cryptic C4-dicarboxylate transporter DcuD complement(577039..578406) Escherichia coli O104:H4 str. 2011C-3493 13699237 YP_006777297.1 CDS O3K_02835 NC_018658.1 578786 579577 D COG2186 Transcriptional regulators; transcriptional regulator NanR 578786..579577 Escherichia coli O104:H4 str. 2011C-3493 13699238 YP_006777298.1 CDS O3K_02840 NC_018658.1 579699 580592 D COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; N-acetylneuraminate lyase 579699..580592 Escherichia coli O104:H4 str. 2011C-3493 13699239 YP_006777299.1 CDS O3K_02845 NC_018658.1 580701 582191 D COG0477 Permeases of the major facilitator superfamily; putative sialic acid transporter 580701..582191 Escherichia coli O104:H4 str. 2011C-3493 13699240 YP_006777300.1 CDS O3K_02850 NC_018658.1 582239 582928 D COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; N-acetylmannosamine-6-phosphate 2-epimerase 582239..582928 Escherichia coli O104:H4 str. 2011C-3493 13699241 YP_006777301.1 CDS O3K_02855 NC_018658.1 582925 583800 D COG1940 Transcriptional regulator/sugar kinase; N-acetylmannosamine kinase 582925..583800 Escherichia coli O104:H4 str. 2011C-3493 13699242 YP_006777302.1 CDS O3K_02860 NC_018658.1 583797 584261 D COG2731 Beta-galactosidase, beta subunit; hypothetical protein 583797..584261 Escherichia coli O104:H4 str. 2011C-3493 13699243 YP_006777303.1 CDS O3K_02865 NC_018658.1 584337 584642 R IS600 orf complement(584337..584642) Escherichia coli O104:H4 str. 2011C-3493 13699244 YP_006777304.1 CDS O3K_02870 NC_018658.1 584659 585138 R COG4804 Uncharacterized conserved protein; hypothetical protein complement(584659..585138) Escherichia coli O104:H4 str. 2011C-3493 13699245 YP_006777305.1 CDS gltD NC_018658.1 585322 586740 R COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; glutamate synthase subunit beta complement(585322..586740) Escherichia coli O104:H4 str. 2011C-3493 13699246 YP_006777306.1 CDS gltB NC_018658.1 586753 591213 R COG0067 Glutamate synthase domain 1; glutamate synthase subunit alpha complement(586753..591213) Escherichia coli O104:H4 str. 2011C-3493 13699247 YP_006777307.1 CDS O3K_02885 NC_018658.1 591888 592817 D COG1242 Predicted Fe-S oxidoreductase; Fe-S oxidoreductase 591888..592817 Escherichia coli O104:H4 str. 2011C-3493 13699248 YP_006777308.1 CDS O3K_02890 NC_018658.1 592913 595249 D COG0642 Signal transduction histidine kinase; aerobic respiration control sensor protein ArcB 592913..595249 Escherichia coli O104:H4 str. 2011C-3493 13699249 YP_006777309.1 CDS O3K_02895 NC_018658.1 595479 596132 D COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis; isoprenoid biosynthesis protein 595479..596132 Escherichia coli O104:H4 str. 2011C-3493 13699250 YP_006777310.1 CDS mtgA NC_018658.1 596129 596857 D COG0744 Membrane carboxypeptidase (penicillin-binding protein); monofunctional biosynthetic peptidoglycan transglycosylase 596129..596857 Escherichia coli O104:H4 str. 2011C-3493 13699251 YP_006777311.1 CDS O3K_02905 NC_018658.1 596854 597486 R hypothetical protein complement(596854..597486) Escherichia coli O104:H4 str. 2011C-3493 13699252 YP_006777312.1 CDS O3K_02910 NC_018658.1 597699 597971 R COG1925 Phosphotransferase system, HPr-related proteins; PTS system phosphohistidinoprotein-hexose phosphotransferase Npr complement(597699..597971) Escherichia coli O104:H4 str. 2011C-3493 13699253 YP_006777313.1 CDS O3K_02915 NC_018658.1 597968 598822 R COG1660 Predicted P-loop-containing kinase; glmZ(sRNA)-inactivating NTPase complement(597968..598822) Escherichia coli O104:H4 str. 2011C-3493 13699254 YP_006777314.1 CDS O3K_02920 NC_018658.1 598868 599359 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system sugar transporter subunit IIA complement(598868..599359) Escherichia coli O104:H4 str. 2011C-3493 13699255 YP_006777315.1 CDS O3K_02925 NC_018658.1 599477 599764 R COG1544 Ribosome-associated protein Y (PSrp-1); ribosome hibernation promoting factor HPF complement(599477..599764) Escherichia coli O104:H4 str. 2011C-3493 13699256 YP_006777316.1 CDS O3K_02930 NC_018658.1 599787 601220 R COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; RNA polymerase factor sigma-54 complement(599787..601220) Escherichia coli O104:H4 str. 2011C-3493 13699257 YP_006777317.1 CDS O3K_02935 NC_018658.1 601268 601993 R COG1137 ABC-type (unclassified) transport system, ATPase component; lipopolysaccharide ABC transporter ATP-binding protein complement(601268..601993) Escherichia coli O104:H4 str. 2011C-3493 13699258 YP_006777318.1 CDS O3K_02940 NC_018658.1 602000 602557 R COG1934 Uncharacterized protein conserved in bacteria; lipopolysaccharide transport periplasmic protein LptA complement(602000..602557) Escherichia coli O104:H4 str. 2011C-3493 13699259 YP_006777319.1 CDS O3K_02945 NC_018658.1 602526 603101 R COG3117 Uncharacterized protein conserved in bacteria; lipopolysaccharide exporter periplasmic protein complement(602526..603101) Escherichia coli O104:H4 str. 2011C-3493 13699260 YP_006777320.1 CDS O3K_02950 NC_018658.1 603098 603664 R COG1778 Low specificity phosphatase (HAD superfamily); 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase complement(603098..603664) Escherichia coli O104:H4 str. 2011C-3493 13699261 YP_006777321.1 CDS O3K_02955 NC_018658.1 603685 604671 R COG0794 Predicted sugar phosphate isomerase involved in capsule formation; D-arabinose 5-phosphate isomerase complement(603685..604671) Escherichia coli O104:H4 str. 2011C-3493 13699262 YP_006777322.1 CDS O3K_02960 NC_018658.1 604685 605662 R COG0530 Ca2+/Na+ antiporter; putative calcium/sodium:proton antiporter complement(604685..605662) Escherichia coli O104:H4 str. 2011C-3493 13699263 YP_006777323.1 CDS O3K_02965 NC_018658.1 605872 606681 D COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; ABC transporter ATP-binding protein YrbF 605872..606681 Escherichia coli O104:H4 str. 2011C-3493 13699264 YP_006777324.1 CDS O3K_02970 NC_018658.1 606689 607471 D COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; toluene ABC transporter permease 606689..607471 Escherichia coli O104:H4 str. 2011C-3493 13699265 YP_006777325.1 CDS O3K_02975 NC_018658.1 607476 608027 D COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; hypothetical protein 607476..608027 Escherichia coli O104:H4 str. 2011C-3493 13699266 YP_006777326.1 CDS O3K_02980 NC_018658.1 608046 608681 D COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component; ABC transporter substrate-binding protein MlaC 608046..608681 Escherichia coli O104:H4 str. 2011C-3493 13699267 YP_006777327.1 CDS O3K_02985 NC_018658.1 608681 608974 D COG3113 Predicted NTP binding protein (contains STAS domain); hypothetical protein 608681..608974 Escherichia coli O104:H4 str. 2011C-3493 13699268 YP_006777328.1 CDS O3K_02990 NC_018658.1 609134 609388 D COG5007 Predicted transcriptional regulator, BolA superfamily; putative DNA-binding transcriptional regulator 609134..609388 Escherichia coli O104:H4 str. 2011C-3493 13699269 YP_006777329.1 CDS O3K_02995 NC_018658.1 609443 610702 D COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 609443..610702 Escherichia coli O104:H4 str. 2011C-3493 13699270 YP_006777330.1 CDS O3K_03000 NC_018658.1 610750 611028 R COG3423 Predicted transcriptional regulator; DNA-binding transcriptional regulator Nlp complement(610750..611028) Escherichia coli O104:H4 str. 2011C-3493 13699271 YP_006777331.1 CDS O3K_03005 NC_018658.1 611256 612227 R COG0142 Geranylgeranyl pyrophosphate synthase; octaprenyl diphosphate synthase complement(611256..612227) Escherichia coli O104:H4 str. 2011C-3493 13699272 YP_006777332.1 CDS rplU NC_018658.1 612486 612797 D COG0261 Ribosomal protein L21; 50S ribosomal protein L21 612486..612797 Escherichia coli O104:H4 str. 2011C-3493 13699273 YP_006777333.1 CDS rpmA NC_018658.1 612818 613075 D COG0211 Ribosomal protein L27; 50S ribosomal protein L27 612818..613075 Escherichia coli O104:H4 str. 2011C-3493 13699274 YP_006777334.1 CDS O3K_03020 NC_018658.1 613202 614167 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 613202..614167 Escherichia coli O104:H4 str. 2011C-3493 13699275 YP_006777335.1 CDS obgE NC_018658.1 614183 615355 D COG0536 Predicted GTPase; GTPase CgtA 614183..615355 Escherichia coli O104:H4 str. 2011C-3493 13699276 YP_006777336.1 CDS O3K_03030 NC_018658.1 615395 616828 R COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); D-alanyl-D-alanine carboxypeptidase complement(615395..616828) Escherichia coli O104:H4 str. 2011C-3493 13699277 YP_006777337.1 CDS greA NC_018658.1 617076 617552 D COG0782 Transcription elongation factor; transcription elongation factor GreA 617076..617552 Escherichia coli O104:H4 str. 2011C-3493 13699278 YP_006777338.1 CDS O3K_03040 NC_018658.1 617708 618001 R COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; RNA-binding protein YhbY complement(617708..618001) Escherichia coli O104:H4 str. 2011C-3493 13699279 YP_006777339.1 CDS rrmJ NC_018658.1 618127 618756 D COG0293 23S rRNA methylase; 23S rRNA methyltransferase J 618127..618756 Escherichia coli O104:H4 str. 2011C-3493 13699280 YP_006777340.1 CDS hflB NC_018658.1 618856 620790 D COG0465 ATP-dependent Zn proteases; ATP-dependent metalloprotease 618856..620790 Escherichia coli O104:H4 str. 2011C-3493 13699281 YP_006777341.1 CDS folP NC_018658.1 620880 621728 D COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase 620880..621728 Escherichia coli O104:H4 str. 2011C-3493 13699282 YP_006777342.1 CDS glmM NC_018658.1 621721 623058 D COG1109 Phosphomannomutase; phosphoglucosamine mutase 621721..623058 Escherichia coli O104:H4 str. 2011C-3493 13699283 YP_006777343.1 CDS secG NC_018658.1 623286 623618 D COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 623286..623618 Escherichia coli O104:H4 str. 2011C-3493 13699284 YP_006777344.1 CDS O3K_03070 NC_018658.1 624176 625801 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; hydrolase, inner membrane 624176..625801 Escherichia coli O104:H4 str. 2011C-3493 13699286 YP_006777345.1 CDS O3K_03075 NC_018658.1 625809 627152 R COG0137 Argininosuccinate synthase; argininosuccinate synthase complement(625809..627152) Escherichia coli O104:H4 str. 2011C-3493 13699287 YP_006777346.1 CDS O3K_03080 NC_018658.1 627783 628235 D COG0779 Uncharacterized protein conserved in bacteria; ribosome maturation protein RimP 627783..628235 Escherichia coli O104:H4 str. 2011C-3493 13699289 YP_006777347.1 CDS nusA NC_018658.1 628263 629750 D COG0195 Transcription elongation factor; transcription elongation factor NusA 628263..629750 Escherichia coli O104:H4 str. 2011C-3493 13699290 YP_006777348.1 CDS infB NC_018658.1 629775 632447 D COG0532 Translation initiation factor 2 (IF-2; GTPase); translation initiation factor IF-2 629775..632447 Escherichia coli O104:H4 str. 2011C-3493 13699291 YP_006777349.1 CDS rbfA NC_018658.1 632611 633012 D COG0858 Ribosome-binding factor A; ribosome-binding factor A 632611..633012 Escherichia coli O104:H4 str. 2011C-3493 13699292 YP_006777350.1 CDS truB NC_018658.1 633012 633956 D COG0130 Pseudouridine synthase; tRNA pseudouridine synthase B 633012..633956 Escherichia coli O104:H4 str. 2011C-3493 13700297 YP_006777351.1 CDS rpsO NC_018658.1 634105 634374 D COG0184 Ribosomal protein S15P/S13E; 30S ribosomal protein S15 634105..634374 Escherichia coli O104:H4 str. 2011C-3493 13700298 YP_006777352.1 CDS O3K_03110 NC_018658.1 634621 636756 D COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 634621..636756 Escherichia coli O104:H4 str. 2011C-3493 13700299 YP_006777353.1 CDS O3K_03115 NC_018658.1 636865 637749 D COG4785 Lipoprotein NlpI, contains TPR repeats; lipoprotein NlpI 636865..637749 Escherichia coli O104:H4 str. 2011C-3493 13700300 YP_006777354.1 CDS O3K_03120 NC_018658.1 637929 639818 D COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase DeaD 637929..639818 Escherichia coli O104:H4 str. 2011C-3493 13700301 YP_006777355.1 CDS O3K_03125 NC_018658.1 639819 639956 R hypothetical protein complement(639819..639956) Escherichia coli O104:H4 str. 2011C-3493 13700302 YP_006777356.1 CDS O3K_03130 NC_018658.1 639972 641216 D COG0814 Amino acid permeases; tryptophan permease 639972..641216 Escherichia coli O104:H4 str. 2011C-3493 13700303 YP_006777357.1 CDS O3K_03135 NC_018658.1 641334 642341 R COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein complement(641334..642341) Escherichia coli O104:H4 str. 2011C-3493 13700304 YP_006777358.1 CDS O3K_03140 NC_018658.1 642547 643425 R COG0826 Collagenase and related proteases; protease complement(642547..643425) Escherichia coli O104:H4 str. 2011C-3493 13700305 YP_006777359.1 CDS O3K_03145 NC_018658.1 643434 644429 R COG0826 Collagenase and related proteases; peptidase, U32 family protein complement(643434..644429) Escherichia coli O104:H4 str. 2011C-3493 13700306 YP_006777360.1 CDS O3K_03150 NC_018658.1 644638 645162 D COG3154 Putative lipid carrier protein; lipid carrier protein 644638..645162 Escherichia coli O104:H4 str. 2011C-3493 13700307 YP_006777361.1 CDS O3K_03155 NC_018658.1 645156 645659 D COG3153 Predicted acetyltransferase; hypothetical protein 645156..645659 Escherichia coli O104:H4 str. 2011C-3493 13700308 YP_006777362.1 CDS O3K_03160 NC_018658.1 645646 645948 R COG2827 Predicted endonuclease containing a URI domain; GIY-YIG nuclease superfamily protein complement(645646..645948) Escherichia coli O104:H4 str. 2011C-3493 13700309 YP_006777363.1 CDS O3K_03165 NC_018658.1 645999 646442 D COG3787 Uncharacterized protein conserved in bacteria; hypothetical protein 645999..646442 Escherichia coli O104:H4 str. 2011C-3493 13700310 YP_006777364.1 CDS O3K_03170 NC_018658.1 646422 646940 R COG0693 Putative intracellular protease/amidase; hypothetical protein complement(646422..646940) Escherichia coli O104:H4 str. 2011C-3493 13700311 YP_006777365.1 CDS O3K_03175 NC_018658.1 647068 647703 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; nucleoside-diphosphate-sugar epimerase 647068..647703 Escherichia coli O104:H4 str. 2011C-3493 13700312 YP_006777366.1 CDS O3K_03180 NC_018658.1 647776 648816 D COG0701 Predicted permeases; permease 647776..648816 Escherichia coli O104:H4 str. 2011C-3493 13700313 YP_006777367.1 CDS O3K_03185 NC_018658.1 648930 649505 R COG2823 Predicted periplasmic or secreted lipoprotein; outer membrane lipoprotein complement(648930..649505) Escherichia coli O104:H4 str. 2011C-3493 13700314 YP_006777368.1 CDS O3K_03190 NC_018658.1 649515 650105 R COG0279 Phosphoheptose isomerase; DnaA initiator-associating protein DiaA complement(649515..650105) Escherichia coli O104:H4 str. 2011C-3493 13700315 YP_006777369.1 CDS O3K_03195 NC_018658.1 650125 650520 R COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein complement(650125..650520) Escherichia coli O104:H4 str. 2011C-3493 13700316 YP_006777370.1 CDS O3K_03200 NC_018658.1 650478 652514 R COG3107 Putative lipoprotein; LppC family lipoprotein complement(650478..652514) Escherichia coli O104:H4 str. 2011C-3493 13700317 YP_006777371.1 CDS O3K_03205 NC_018658.1 652578 653438 D COG0313 Predicted methyltransferases; SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase 652578..653438 Escherichia coli O104:H4 str. 2011C-3493 13700318 YP_006777372.1 CDS O3K_03210 NC_018658.1 653481 654572 R COG3539 P pilus assembly protein, pilin FimA; putative fimbrial protein complement(653481..654572) Escherichia coli O104:H4 str. 2011C-3493 13700319 YP_006777373.1 CDS O3K_03215 NC_018658.1 654583 657099 R COG3188 P pilus assembly protein, porin PapC; outer membrane protein complement(654583..657099) Escherichia coli O104:H4 str. 2011C-3493 13700320 YP_006777374.1 CDS O3K_03220 NC_018658.1 657129 657824 R COG3121 P pilus assembly protein, chaperone PapD; putative periplasmic pilin chaperone complement(657129..657824) Escherichia coli O104:H4 str. 2011C-3493 13700321 YP_006777375.1 CDS O3K_03225 NC_018658.1 657904 658488 R COG3539 P pilus assembly protein, pilin FimA; putative fimbrial-like adhesin protein complement(657904..658488) Escherichia coli O104:H4 str. 2011C-3493 13700322 YP_006777376.1 CDS O3K_03230 NC_018658.1 658888 659643 R COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; galactosamine-6-phosphate isomerase complement(658888..659643) Escherichia coli O104:H4 str. 2011C-3493 13700323 YP_006777377.1 CDS O3K_03235 NC_018658.1 659644 660435 R COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system N-acetylgalactosamine-specific transporter subunit IID complement(659644..660435) Escherichia coli O104:H4 str. 2011C-3493 13700324 YP_006777378.1 CDS O3K_03240 NC_018658.1 660425 661228 R COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system N-acetylgalactosamine-specific transporter subunit IIC complement(660425..661228) Escherichia coli O104:H4 str. 2011C-3493 13700325 YP_006777379.1 CDS O3K_03245 NC_018658.1 661267 661743 R COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(661267..661743) Escherichia coli O104:H4 str. 2011C-3493 13700326 YP_006777380.1 CDS kbaY NC_018658.1 661910 662770 R COG0191 Fructose/tagatose bisphosphate aldolase; tagatose-bisphosphate aldolase complement(661910..662770) Escherichia coli O104:H4 str. 2011C-3493 13700327 YP_006777381.1 CDS O3K_03255 NC_018658.1 662783 663937 R COG2222 Predicted phosphosugar isomerases; tagatose-6-phosphate ketose/aldose isomerase complement(662783..663937) Escherichia coli O104:H4 str. 2011C-3493 13700328 YP_006777382.1 CDS O3K_03260 NC_018658.1 664287 665420 R COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase complement(664287..665420) Escherichia coli O104:H4 str. 2011C-3493 13700329 YP_006777383.1 CDS O3K_03265 NC_018658.1 665417 665851 R COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system transporter subunit IIA complement(665417..665851) Escherichia coli O104:H4 str. 2011C-3493 13700330 YP_006777384.1 CDS O3K_03270 NC_018658.1 665869 666747 R COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system hexose/hexosamine family transporter permease IID complement(665869..666747) Escherichia coli O104:H4 str. 2011C-3493 13700331 YP_006777385.1 CDS O3K_03275 NC_018658.1 666737 667516 R COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system N-acetylgalactosamine-specific transporter subunit IIC complement(666737..667516) Escherichia coli O104:H4 str. 2011C-3493 13700332 YP_006777386.1 CDS O3K_03280 NC_018658.1 667527 668000 R COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(667527..668000) Escherichia coli O104:H4 str. 2011C-3493 13700333 YP_006777387.1 CDS O3K_03285 NC_018658.1 668023 669303 R COG4573 Predicted tagatose 6-phosphate kinase; tagatose 6-phosphate aldolase subunit KbaZ complement(668023..669303) Escherichia coli O104:H4 str. 2011C-3493 13700334 YP_006777388.1 CDS O3K_03290 NC_018658.1 669552 670361 D COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional regulator AgaR 669552..670361 Escherichia coli O104:H4 str. 2011C-3493 13700335 YP_006777389.1 CDS O3K_03295 NC_018658.1 670416 670880 R hypothetical protein complement(670416..670880) Escherichia coli O104:H4 str. 2011C-3493 13700336 YP_006777390.1 CDS O3K_03300 NC_018658.1 670880 671215 R COG2002 Regulators of stationary/sporulation gene expression; putative regulator PrlF complement(670880..671215) Escherichia coli O104:H4 str. 2011C-3493 13700337 YP_006777391.1 CDS O3K_03305 NC_018658.1 671364 672935 R COG2721 Altronate dehydratase; galactarate dehydratase complement(671364..672935) Escherichia coli O104:H4 str. 2011C-3493 13700338 YP_006777392.1 CDS O3K_03310 NC_018658.1 673309 674643 D COG0477 Permeases of the major facilitator superfamily; galactarate transporter 673309..674643 Escherichia coli O104:H4 str. 2011C-3493 13700339 YP_006777393.1 CDS O3K_03315 NC_018658.1 674659 675429 D COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; alpha-dehydro-beta-deoxy-D-glucarate aldolase 674659..675429 Escherichia coli O104:H4 str. 2011C-3493 13700340 YP_006777394.1 CDS garR NC_018658.1 675459 676349 D COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; tartronate semialdehyde reductase 675459..676349 Escherichia coli O104:H4 str. 2011C-3493 13700341 YP_006777395.1 CDS O3K_03325 NC_018658.1 676446 677591 D COG1929 Glycerate kinase; glycerate kinase 676446..677591 Escherichia coli O104:H4 str. 2011C-3493 13700342 YP_006777396.1 CDS O3K_03330 NC_018658.1 678462 679442 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(678462..679442) Escherichia coli O104:H4 str. 2011C-3493 13700343 YP_006777397.1 CDS O3K_03335 NC_018658.1 679780 680967 R hypothetical protein complement(679780..680967) Escherichia coli O104:H4 str. 2011C-3493 13700344 YP_006777398.1 CDS O3K_03340 NC_018658.1 680989 681528 R COG0443 Molecular chaperone; hypothetical protein complement(680989..681528) Escherichia coli O104:H4 str. 2011C-3493 13700345 YP_006777399.1 CDS O3K_03345 NC_018658.1 681784 682140 R DNA-binding transcriptional activator TdcR complement(681784..682140) Escherichia coli O104:H4 str. 2011C-3493 13700346 YP_006777400.1 CDS O3K_03350 NC_018658.1 682317 683255 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator TdcA 682317..683255 Escherichia coli O104:H4 str. 2011C-3493 13700347 YP_006777401.1 CDS O3K_03355 NC_018658.1 683354 684343 D COG1171 Threonine dehydratase; threonine dehydratase 683354..684343 Escherichia coli O104:H4 str. 2011C-3493 13700348 YP_006777402.1 CDS O3K_03360 NC_018658.1 684365 685696 D COG0814 Amino acid permeases; threonine/serine transporter TdcC 684365..685696 Escherichia coli O104:H4 str. 2011C-3493 13700349 YP_006777403.1 CDS O3K_03365 NC_018658.1 685722 686930 D COG0282 Acetate kinase; propionate/acetate kinase 685722..686930 Escherichia coli O104:H4 str. 2011C-3493 13700350 YP_006777404.1 CDS O3K_03370 NC_018658.1 686964 689258 D COG1882 Pyruvate-formate lyase; Keto-acid formate acetyltransferase 686964..689258 Escherichia coli O104:H4 str. 2011C-3493 13700351 YP_006777405.1 CDS O3K_03375 NC_018658.1 689272 689661 D COG0251 Putative translation initiation inhibitor, yjgF family; putative endoribonuclease L-PSP 689272..689661 Escherichia coli O104:H4 str. 2011C-3493 13700352 YP_006777406.1 CDS O3K_03380 NC_018658.1 689733 691097 D COG1760 L-serine deaminase; L-serine dehydratase TdcG 689733..691097 Escherichia coli O104:H4 str. 2011C-3493 13700353 YP_006777407.1 CDS O3K_03385 NC_018658.1 691372 692703 D COG0814 Amino acid permeases; transporter 691372..692703 Escherichia coli O104:H4 str. 2011C-3493 13700354 YP_006777408.1 CDS O3K_03390 NC_018658.1 692731 694041 D COG3681 Uncharacterized conserved protein; hypothetical protein 692731..694041 Escherichia coli O104:H4 str. 2011C-3493 13700355 YP_006777409.1 CDS O3K_03395 NC_018658.1 694102 694266 R hypothetical protein complement(694102..694266) Escherichia coli O104:H4 str. 2011C-3493 13700356 YP_006777410.1 CDS O3K_03400 NC_018658.1 694289 694990 R COG1741 Pirin-related protein; putative pirin-related protein complement(694289..694990) Escherichia coli O104:H4 str. 2011C-3493 13700357 YP_006777411.1 CDS O3K_03405 NC_018658.1 695095 695991 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 695095..695991 Escherichia coli O104:H4 str. 2011C-3493 13700358 YP_006777412.1 CDS O3K_03410 NC_018658.1 696035 696538 R COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' complement(696035..696538) Escherichia coli O104:H4 str. 2011C-3493 13700359 YP_006777413.1 CDS O3K_03415 NC_018658.1 696457 696681 R COG3677 Transposase and inactivated derivatives; IS1 repressor A complement(696457..696681) Escherichia coli O104:H4 str. 2011C-3493 13700360 YP_006777414.1 CDS O3K_03420 NC_018658.1 696842 697207 R COG3152 Predicted membrane protein; hypothetical protein complement(696842..697207) Escherichia coli O104:H4 str. 2011C-3493 13700361 YP_006777415.1 CDS O3K_03425 NC_018658.1 697500 698486 R COG0435 Predicted glutathione S-transferase; putative transferase complement(697500..698486) Escherichia coli O104:H4 str. 2011C-3493 13700362 YP_006777416.1 CDS O3K_03430 NC_018658.1 698556 698948 R COG2259 Predicted membrane protein; hypothetical protein complement(698556..698948) Escherichia coli O104:H4 str. 2011C-3493 13700363 YP_006777417.1 CDS O3K_03435 NC_018658.1 699134 699433 R hypothetical protein complement(699134..699433) Escherichia coli O104:H4 str. 2011C-3493 13700364 YP_006777418.1 CDS O3K_03440 NC_018658.1 699423 699827 R hypothetical protein complement(699423..699827) Escherichia coli O104:H4 str. 2011C-3493 13700365 YP_006777419.1 CDS O3K_03445 NC_018658.1 699830 700135 R COG4575 Uncharacterized conserved protein; hypothetical protein complement(699830..700135) Escherichia coli O104:H4 str. 2011C-3493 13700366 YP_006777420.1 CDS O3K_03450 NC_018658.1 700173 700541 R hypothetical protein complement(700173..700541) Escherichia coli O104:H4 str. 2011C-3493 13700367 YP_006777421.1 CDS O3K_03455 NC_018658.1 700688 701071 R EnvZ/OmpR regulon moderator complement(700688..701071) Escherichia coli O104:H4 str. 2011C-3493 13700368 YP_006777422.1 CDS O3K_03460 NC_018658.1 701075 701737 R COG0586 Uncharacterized membrane-associated protein; hypothetical protein complement(701075..701737) Escherichia coli O104:H4 str. 2011C-3493 13700369 YP_006777423.1 CDS O3K_03465 NC_018658.1 702082 702858 R COG2186 Transcriptional regulators; DNA-binding transcriptional repressor ExuR complement(702082..702858) Escherichia coli O104:H4 str. 2011C-3493 13700370 YP_006777424.1 CDS O3K_03470 NC_018658.1 703154 703870 D putative fimbrial protein 703154..703870 Escherichia coli O104:H4 str. 2011C-3493 13700371 YP_006777425.1 CDS O3K_03475 NC_018658.1 703900 704400 D putative fimbrial subunit 703900..704400 Escherichia coli O104:H4 str. 2011C-3493 13700372 YP_006777426.1 CDS O3K_03480 NC_018658.1 704474 707176 D hypothetical protein 704474..707176 Escherichia coli O104:H4 str. 2011C-3493 13700373 YP_006777427.1 CDS O3K_03485 NC_018658.1 707173 708261 D hypothetical protein 707173..708261 Escherichia coli O104:H4 str. 2011C-3493 13700374 YP_006777428.1 CDS O3K_03490 NC_018658.1 708349 709647 R COG0477 Permeases of the major facilitator superfamily; hexuronate transporter complement(708349..709647) Escherichia coli O104:H4 str. 2011C-3493 13700375 YP_006777429.1 CDS O3K_03495 NC_018658.1 710130 711542 D COG1904 Glucuronate isomerase; glucuronate isomerase 710130..711542 Escherichia coli O104:H4 str. 2011C-3493 13700376 YP_006777430.1 CDS O3K_03500 NC_018658.1 711557 713044 D COG2721 Altronate dehydratase; altronate hydrolase 711557..713044 Escherichia coli O104:H4 str. 2011C-3493 13700377 YP_006777431.1 CDS O3K_03505 NC_018658.1 713127 713678 D inner membrane protein 713127..713678 Escherichia coli O104:H4 str. 2011C-3493 13700378 YP_006777432.1 CDS O3K_03510 NC_018658.1 713683 714927 R COG3633 Na+/serine symporter; serine/threonine transporter SstT complement(713683..714927) Escherichia coli O104:H4 str. 2011C-3493 13700379 YP_006777433.1 CDS O3K_03515 NC_018658.1 715326 716291 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; inner membrane protein complement(715326..716291) Escherichia coli O104:H4 str. 2011C-3493 13700380 YP_006777434.1 CDS O3K_03520 NC_018658.1 716574 717560 R COG0673 Predicted dehydrogenases and related proteins; NAD(P)-binding dehydrogenase complement(716574..717560) Escherichia coli O104:H4 str. 2011C-3493 13700381 YP_006777435.1 CDS O3K_03525 NC_018658.1 717639 718322 R COG2949 Uncharacterized membrane protein; thioredoxin-like protein complement(717639..718322) Escherichia coli O104:H4 str. 2011C-3493 13700382 YP_006777436.1 CDS O3K_03530 NC_018658.1 718399 718902 R COG1451 Predicted metal-dependent hydrolase; hypothetical protein complement(718399..718902) Escherichia coli O104:H4 str. 2011C-3493 13700383 YP_006777437.1 CDS O3K_03535 NC_018658.1 718987 720123 D COG2813 16S RNA G1207 methylase RsmC; SAM-dependent 23S ribosomal RNA mG1835 methyltransferase 718987..720123 Escherichia coli O104:H4 str. 2011C-3493 13700384 YP_006777438.1 CDS O3K_03540 NC_018658.1 720227 720397 D hypothetical protein 720227..720397 Escherichia coli O104:H4 str. 2011C-3493 13700385 YP_006777439.1 CDS O3K_03545 NC_018658.1 720394 720810 D COG5499 Predicted transcription regulator containing HTH domain; putative DNA-binding transcriptional regulator 720394..720810 Escherichia coli O104:H4 str. 2011C-3493 13700386 YP_006777440.1 CDS O3K_03550 NC_018658.1 720855 722873 R COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; 2,4-dienoyl-CoA reductase complement(720855..722873) Escherichia coli O104:H4 str. 2011C-3493 13700387 YP_006777441.1 CDS O3K_03555 NC_018658.1 723199 725550 R COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; alpha-glucosidase complement(723199..725550) Escherichia coli O104:H4 str. 2011C-3493 13700388 YP_006777442.1 CDS O3K_03560 NC_018658.1 725567 726637 R hypothetical protein complement(725567..726637) Escherichia coli O104:H4 str. 2011C-3493 13700389 YP_006777443.1 CDS O3K_03565 NC_018658.1 726771 728204 R COG0531 Amino acid transporters; transporter complement(726771..728204) Escherichia coli O104:H4 str. 2011C-3493 13700390 YP_006777444.1 CDS ebgC NC_018658.1 728267 728716 R COG2731 Beta-galactosidase, beta subunit; cryptic beta-D-galactosidase subunit beta complement(728267..728716) Escherichia coli O104:H4 str. 2011C-3493 13700391 YP_006777445.1 CDS ebgA NC_018658.1 728713 731805 R COG3250 Beta-galactosidase/beta-glucuronidase; cryptic beta-D-galactosidase subunit alpha complement(728713..731805) Escherichia coli O104:H4 str. 2011C-3493 13700392 YP_006777446.1 CDS O3K_03580 NC_018658.1 731989 732972 R COG1609 Transcriptional regulators; DNA-binding transcriptional repressor EbgR complement(731989..732972) Escherichia coli O104:H4 str. 2011C-3493 13700393 YP_006777447.1 CDS O3K_03585 NC_018658.1 733191 733523 D COG0073 EMAP domain; tRNA-binding protein 733191..733523 Escherichia coli O104:H4 str. 2011C-3493 13700394 YP_006777448.1 CDS O3K_03590 NC_018658.1 733565 734971 R COG4992 Ornithine/acetylornithine aminotransferase; putrescine--2-oxoglutarate aminotransferase complement(733565..734971) Escherichia coli O104:H4 str. 2011C-3493 13700395 YP_006777449.1 CDS O3K_03595 NC_018658.1 735362 736882 D COG2202 FOG: PAS/PAC domain; signal transducer for aerotaxis/methyl accepting chemotaxis protein 735362..736882 Escherichia coli O104:H4 str. 2011C-3493 13700396 YP_006777450.1 CDS O3K_03600 NC_018658.1 737036 737659 R COG1695 Predicted transcriptional regulators; transcriptional regulator complement(737036..737659) Escherichia coli O104:H4 str. 2011C-3493 13700397 YP_006777451.1 CDS O3K_03605 NC_018658.1 737936 738700 D COG2375 Siderophore-interacting protein; siderophore-interacting protein 737936..738700 Escherichia coli O104:H4 str. 2011C-3493 13700398 YP_006777452.1 CDS O3K_03610 NC_018658.1 738954 739460 D COG3663 G:T/U mismatch-specific DNA glycosylase; G/U mismatch-specific DNA glycosylase 738954..739460 Escherichia coli O104:H4 str. 2011C-3493 13700400 YP_006777453.1 CDS O3K_03615 NC_018658.1 739538 741379 R COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor RpoD complement(739538..741379) Escherichia coli O104:H4 str. 2011C-3493 13700401 YP_006777454.1 CDS dnaG NC_018658.1 741574 743319 R COG0358 DNA primase (bacterial type); DNA primase complement(741574..743319) Escherichia coli O104:H4 str. 2011C-3493 13700402 YP_006777455.1 CDS rpsU NC_018658.1 743430 743645 R COG0828 Ribosomal protein S21; 30S ribosomal protein S21 complement(743430..743645) Escherichia coli O104:H4 str. 2011C-3493 13700403 YP_006777456.1 CDS O3K_03630 NC_018658.1 743882 744895 D COG0533 Metal-dependent proteases with possible chaperone activity; UGMP family protein 743882..744895 Escherichia coli O104:H4 str. 2011C-3493 13700404 YP_006777457.1 CDS O3K_03635 NC_018658.1 744938 746401 R COG0471 Di- and tricarboxylate transporters; tartrate:succinate antiporter complement(744938..746401) Escherichia coli O104:H4 str. 2011C-3493 13700405 YP_006777458.1 CDS O3K_03640 NC_018658.1 746450 747055 R COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain; L(+)-tartrate dehydratase subunit beta complement(746450..747055) Escherichia coli O104:H4 str. 2011C-3493 13700406 YP_006777459.1 CDS O3K_03645 NC_018658.1 747052 747963 R COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; tartrate dehydratase subunit alpha complement(747052..747963) Escherichia coli O104:H4 str. 2011C-3493 13700407 YP_006777460.1 CDS O3K_03650 NC_018658.1 748170 749102 D COG0583 Transcriptional regulator; transcriptional activator TtdR 748170..749102 Escherichia coli O104:H4 str. 2011C-3493 13700408 YP_006777461.1 CDS O3K_03655 NC_018658.1 749115 749732 R COG0344 Predicted membrane protein; putative glycerol-3-phosphate acyltransferase PlsY complement(749115..749732) Escherichia coli O104:H4 str. 2011C-3493 13700409 YP_006777462.1 CDS folB NC_018658.1 749837 750205 D COG1539 Dihydroneopterin aldolase; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 749837..750205 Escherichia coli O104:H4 str. 2011C-3493 13700410 YP_006777463.1 CDS O3K_03665 NC_018658.1 750296 751117 D COG1968 Uncharacterized bacitracin resistance protein; undecaprenyl pyrophosphate phosphatase 750296..751117 Escherichia coli O104:H4 str. 2011C-3493 13700411 YP_006777464.1 CDS cca NC_018658.1 751280 752518 R COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase complement(751280..752518) Escherichia coli O104:H4 str. 2011C-3493 13700412 YP_006777465.1 CDS O3K_03675 NC_018658.1 752582 753202 R COG3103 SH3 domain protein; SH3 domain-containing protein complement(752582..753202) Escherichia coli O104:H4 str. 2011C-3493 13700413 YP_006777466.1 CDS O3K_03680 NC_018658.1 753444 754745 D COG3025 Uncharacterized conserved protein; adenylate cyclase 753444..754745 Escherichia coli O104:H4 str. 2011C-3493 13700414 YP_006777467.1 CDS O3K_03685 NC_018658.1 754768 757608 D COG1391 Glutamine synthetase adenylyltransferase; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 754768..757608 Escherichia coli O104:H4 str. 2011C-3493 13700415 YP_006777468.1 CDS O3K_03690 NC_018658.1 757656 759089 D COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 757656..759089 Escherichia coli O104:H4 str. 2011C-3493 13700416 YP_006777469.1 CDS O3K_03695 NC_018658.1 759532 759783 R hypothetical protein complement(759532..759783) Escherichia coli O104:H4 str. 2011C-3493 13700417 YP_006777470.1 CDS O3K_03700 NC_018658.1 759883 761544 R COG2268 Uncharacterized protein conserved in bacteria; hypothetical protein complement(759883..761544) Escherichia coli O104:H4 str. 2011C-3493 13700418 YP_006777471.1 CDS O3K_03705 NC_018658.1 761571 762200 R inner membrane protein complement(761571..762200) Escherichia coli O104:H4 str. 2011C-3493 13700419 YP_006777472.1 CDS O3K_03710 NC_018658.1 762469 762669 D glycogen synthesis protein GlgS 762469..762669 Escherichia coli O104:H4 str. 2011C-3493 13700420 YP_006777473.1 CDS O3K_03715 NC_018658.1 762712 763776 R hypothetical protein complement(762712..763776) Escherichia coli O104:H4 str. 2011C-3493 13700421 YP_006777474.1 CDS O3K_03720 NC_018658.1 763778 764527 R COG3121 P pilus assembly protein, chaperone PapD; periplasmic pilin chaperone complement(763778..764527) Escherichia coli O104:H4 str. 2011C-3493 13700422 YP_006777475.1 CDS O3K_03725 NC_018658.1 764543 767047 R COG3188 P pilus assembly protein, porin PapC; putative outer membrane usher protein complement(764543..767047) Escherichia coli O104:H4 str. 2011C-3493 13700423 YP_006777476.1 CDS O3K_03730 NC_018658.1 767107 767658 R COG3539 P pilus assembly protein, pilin FimA; putative fimbrial protein complement(767107..767658) Escherichia coli O104:H4 str. 2011C-3493 13700424 YP_006777477.1 CDS O3K_03735 NC_018658.1 767941 768231 R COG2960 Uncharacterized protein conserved in bacteria; hypothetical protein complement(767941..768231) Escherichia coli O104:H4 str. 2011C-3493 13700425 YP_006777478.1 CDS ribB NC_018658.1 768605 769258 D COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase 768605..769258 Escherichia coli O104:H4 str. 2011C-3493 13700426 YP_006777479.1 CDS O3K_03745 NC_018658.1 769519 769689 D hypothetical protein 769519..769689 Escherichia coli O104:H4 str. 2011C-3493 13700427 YP_006777480.1 CDS O3K_03750 NC_018658.1 769747 770520 R COG0428 Predicted divalent heavy-metal cations transporter; zinc transporter ZupT complement(769747..770520) Escherichia coli O104:H4 str. 2011C-3493 13700428 YP_006777481.1 CDS O3K_03755 NC_018658.1 770663 771451 D COG3384 Uncharacterized conserved protein; LigB family dioxygenase 770663..771451 Escherichia coli O104:H4 str. 2011C-3493 13700429 YP_006777482.1 CDS O3K_03760 NC_018658.1 771489 772649 R COG0754 Glutathionylspermidine synthase; hypothetical protein complement(771489..772649) Escherichia coli O104:H4 str. 2011C-3493 13700430 YP_006777483.1 CDS O3K_03765 NC_018658.1 772655 773326 R COG5463 Predicted integral membrane protein; hypothetical protein complement(772655..773326) Escherichia coli O104:H4 str. 2011C-3493 13700431 YP_006777484.1 CDS tolC NC_018658.1 773474 774955 R COG1538 Outer membrane protein; outer membrane channel protein complement(773474..774955) Escherichia coli O104:H4 str. 2011C-3493 13700432 YP_006777485.1 CDS nudF NC_018658.1 775160 775789 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; ADP-ribose pyrophosphatase NudF 775160..775789 Escherichia coli O104:H4 str. 2011C-3493 13700433 YP_006777486.1 CDS O3K_03780 NC_018658.1 775790 776212 D COG3151 Uncharacterized protein conserved in bacteria; putative dehydrogenase 775790..776212 Escherichia coli O104:H4 str. 2011C-3493 13700434 YP_006777487.1 CDS O3K_03785 NC_018658.1 776237 777064 D COG1409 Predicted phosphohydrolases; cyclic 3',5'-adenosine monophosphate phosphodiesterase 776237..777064 Escherichia coli O104:H4 str. 2011C-3493 13700435 YP_006777488.1 CDS O3K_03790 NC_018658.1 777064 777645 D COG3150 Predicted esterase; esterase YqiA 777064..777645 Escherichia coli O104:H4 str. 2011C-3493 13700436 YP_006777489.1 CDS O3K_03795 NC_018658.1 777674 779566 D COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA topoisomerase IV subunit B 777674..779566 Escherichia coli O104:H4 str. 2011C-3493 13700437 YP_006777490.1 CDS O3K_03800 NC_018658.1 779614 779928 R COG1359 Uncharacterized conserved protein; hypothetical protein complement(779614..779928) Escherichia coli O104:H4 str. 2011C-3493 13700438 YP_006777491.1 CDS O3K_03805 NC_018658.1 779959 780540 R COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); Modulator of drug activity B complement(779959..780540) Escherichia coli O104:H4 str. 2011C-3493 13700439 YP_006777492.1 CDS O3K_03810 NC_018658.1 780859 781191 D hypothetical protein 780859..781191 Escherichia coli O104:H4 str. 2011C-3493 13700440 YP_006777493.1 CDS O3K_03815 NC_018658.1 781237 782586 R COG0642 Signal transduction histidine kinase; sensor protein QseC complement(781237..782586) Escherichia coli O104:H4 str. 2011C-3493 13700441 YP_006777494.1 CDS O3K_03820 NC_018658.1 782583 783242 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator QseB complement(782583..783242) Escherichia coli O104:H4 str. 2011C-3493 13700442 YP_006777495.1 CDS O3K_03825 NC_018658.1 783394 783786 D COG3111 Uncharacterized conserved protein; hypothetical protein 783394..783786 Escherichia coli O104:H4 str. 2011C-3493 13700443 YP_006777496.1 CDS O3K_03830 NC_018658.1 783839 784321 D COG3449 DNA gyrase inhibitor; transcriptional regulator 783839..784321 Escherichia coli O104:H4 str. 2011C-3493 13700444 YP_006777497.1 CDS O3K_03835 NC_018658.1 784867 787125 D COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA topoisomerase IV subunit A 784867..787125 Escherichia coli O104:H4 str. 2011C-3493 13700445 YP_006777498.1 CDS O3K_03840 NC_018658.1 787358 788095 D COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 787358..788095 Escherichia coli O104:H4 str. 2011C-3493 13700446 YP_006777499.1 CDS O3K_03845 NC_018658.1 788170 789582 D COG2132 Putative multicopper oxidases; FtsI repressor 788170..789582 Escherichia coli O104:H4 str. 2011C-3493 13700447 YP_006777500.1 CDS O3K_03850 NC_018658.1 789693 791912 D COG1032 Fe-S oxidoreductase; hypothetical protein 789693..791912 Escherichia coli O104:H4 str. 2011C-3493 13700448 YP_006777501.1 CDS O3K_03855 NC_018658.1 791955 792212 R putative outer membrane lipoprotein complement(791955..792212) Escherichia coli O104:H4 str. 2011C-3493 13700449 YP_006777502.1 CDS O3K_03860 NC_018658.1 792263 793189 R hypothetical protein complement(792263..793189) Escherichia coli O104:H4 str. 2011C-3493 13700450 YP_006777503.1 CDS dkgA NC_018658.1 793389 794216 R COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-diketo-D-gluconate reductase A complement(793389..794216) Escherichia coli O104:H4 str. 2011C-3493 13700451 YP_006777504.1 CDS O3K_03870 NC_018658.1 794321 795484 R COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; aldehyde reductase complement(794321..795484) Escherichia coli O104:H4 str. 2011C-3493 13700452 YP_006777505.1 CDS O3K_03875 NC_018658.1 795535 795681 D hypothetical protein 795535..795681 Escherichia coli O104:H4 str. 2011C-3493 13700453 YP_006777506.1 CDS O3K_03880 NC_018658.1 795621 796577 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 795621..796577 Escherichia coli O104:H4 str. 2011C-3493 13700454 YP_006777507.1 CDS O3K_03885 NC_018658.1 796617 797276 R COG0586 Uncharacterized membrane-associated protein; hypothetical protein complement(796617..797276) Escherichia coli O104:H4 str. 2011C-3493 13700455 YP_006777508.1 CDS O3K_03890 NC_018658.1 797416 798603 R COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine beta-lyase complement(797416..798603) Escherichia coli O104:H4 str. 2011C-3493 13700456 YP_006777509.1 CDS O3K_03895 NC_018658.1 798855 799589 D COG0811 Biopolymer transport proteins; biopolymer transport protein ExbB 798855..799589 Escherichia coli O104:H4 str. 2011C-3493 13700457 YP_006777510.1 CDS O3K_03900 NC_018658.1 799596 800021 D COG0848 Biopolymer transport protein; biopolymer transport protein ExbD 799596..800021 Escherichia coli O104:H4 str. 2011C-3493 13700458 YP_006777511.1 CDS O3K_03905 NC_018658.1 800060 800944 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase complement(800060..800944) Escherichia coli O104:H4 str. 2011C-3493 13700459 YP_006777512.1 CDS O3K_03910 NC_018658.1 801135 801629 D COG2862 Predicted membrane protein; hypothetical protein 801135..801629 Escherichia coli O104:H4 str. 2011C-3493 13700460 YP_006777513.1 CDS O3K_03915 NC_018658.1 801669 802709 R COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); L-glyceraldehyde 3-phosphate reductase complement(801669..802709) Escherichia coli O104:H4 str. 2011C-3493 13700461 YP_006777514.1 CDS O3K_03920 NC_018658.1 802866 803753 D COG0412 Dienelactone hydrolase and related enzymes; hypothetical protein 802866..803753 Escherichia coli O104:H4 str. 2011C-3493 13700462 YP_006777515.1 CDS O3K_03925 NC_018658.1 803872 804159 D hypothetical protein 803872..804159 Escherichia coli O104:H4 str. 2011C-3493 13700463 YP_006777516.1 CDS O3K_03930 NC_018658.1 804348 805466 D COG1740 Ni,Fe-hydrogenase I small subunit; hydrogenase 2 small subunit 804348..805466 Escherichia coli O104:H4 str. 2011C-3493 13700464 YP_006777517.1 CDS O3K_03935 NC_018658.1 805469 806455 D COG0437 Fe-S-cluster-containing hydrogenase components 1; hydrogenase 2 protein HybA 805469..806455 Escherichia coli O104:H4 str. 2011C-3493 13700465 YP_006777518.1 CDS O3K_03940 NC_018658.1 806445 807623 D COG5557 Polysulphide reductase; putative hydrogenase 2 b cytochrome subunit 806445..807623 Escherichia coli O104:H4 str. 2011C-3493 13700466 YP_006777519.1 CDS O3K_03945 NC_018658.1 807620 809323 D COG0374 Ni,Fe-hydrogenase I large subunit; hydrogenase 2 large subunit 807620..809323 Escherichia coli O104:H4 str. 2011C-3493 13700467 YP_006777520.1 CDS hybD NC_018658.1 809323 809817 D COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 2 maturation endopeptidase 809323..809817 Escherichia coli O104:H4 str. 2011C-3493 13700468 YP_006777521.1 CDS O3K_03955 NC_018658.1 809810 810298 D hydrogenase 2-specific chaperone 809810..810298 Escherichia coli O104:H4 str. 2011C-3493 13700469 YP_006777522.1 CDS O3K_03960 NC_018658.1 810291 810632 D COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); hydrogenase nickel incorporation protein HybF 810291..810632 Escherichia coli O104:H4 str. 2011C-3493 13700470 YP_006777523.1 CDS O3K_03965 NC_018658.1 810645 810893 D COG0298 Hydrogenase maturation factor; hydrogenase 2 accessory protein HypG 810645..810893 Escherichia coli O104:H4 str. 2011C-3493 13700471 YP_006777524.1 CDS O3K_03970 NC_018658.1 811015 811995 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(811015..811995) Escherichia coli O104:H4 str. 2011C-3493 13700472 YP_006777525.1 CDS O3K_03975 NC_018658.1 812295 813161 R COG0625 Glutathione S-transferase; putative S-transferase complement(812295..813161) Escherichia coli O104:H4 str. 2011C-3493 13700473 YP_006777526.1 CDS O3K_03980 NC_018658.1 813366 815225 D COG0754 Glutathionylspermidine synthase; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 813366..815225 Escherichia coli O104:H4 str. 2011C-3493 13700474 YP_006777527.1 CDS O3K_03985 NC_018658.1 815517 817016 D COG0306 Phosphate/sulphate permeases; phosphate transporter 815517..817016 Escherichia coli O104:H4 str. 2011C-3493 13700475 YP_006777528.1 CDS O3K_03990 NC_018658.1 817065 817757 R COG0125 Thymidylate kinase; hypothetical protein complement(817065..817757) Escherichia coli O104:H4 str. 2011C-3493 13700476 YP_006777529.1 CDS O3K_03995 NC_018658.1 817931 818644 D nucleoside triphosphate hydrolase domain; conserved hypothetical protein; COG0125 Thymidylate kinase; lipoprotein 817931..818644 Escherichia coli O104:H4 str. 2011C-3493 13700477 YP_006777530.1 CDS O3K_04000 NC_018658.1 818676 819434 D COG0178 Excinuclease ATPase subunit; hypothetical protein 818676..819434 Escherichia coli O104:H4 str. 2011C-3493 13700478 YP_006777531.1 CDS O3K_04005 NC_018658.1 819480 820829 D COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; inner membrane protein 819480..820829 Escherichia coli O104:H4 str. 2011C-3493 13700479 YP_006777532.1 CDS O3K_04010 NC_018658.1 820829 821653 D COG0372 Citrate synthase; hypothetical protein 820829..821653 Escherichia coli O104:H4 str. 2011C-3493 13700480 YP_006777533.1 CDS O3K_04015 NC_018658.1 821665 822225 D COG3054 Predicted transcriptional regulator; transcriptional regulator 821665..822225 Escherichia coli O104:H4 str. 2011C-3493 13700481 YP_006777534.1 CDS O3K_04020 NC_018658.1 822256 823326 D COG0795 Predicted permeases; hypothetical protein 822256..823326 Escherichia coli O104:H4 str. 2011C-3493 13700482 YP_006777535.1 CDS O3K_04025 NC_018658.1 823323 824402 D COG0795 Predicted permeases; hypothetical protein 823323..824402 Escherichia coli O104:H4 str. 2011C-3493 13700483 YP_006777536.1 CDS O3K_04030 NC_018658.1 824437 825609 R COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; hypothetical protein complement(824437..825609) Escherichia coli O104:H4 str. 2011C-3493 13700484 YP_006777537.1 CDS O3K_04035 NC_018658.1 825609 825857 R COG0236 Acyl carrier protein; hypothetical protein complement(825609..825857) Escherichia coli O104:H4 str. 2011C-3493 13700485 YP_006777538.1 CDS O3K_04040 NC_018658.1 825889 826803 R COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein complement(825889..826803) Escherichia coli O104:H4 str. 2011C-3493 13700486 YP_006777539.1 CDS O3K_04045 NC_018658.1 826800 828488 R COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; acyl-CoA synthetase complement(826800..828488) Escherichia coli O104:H4 str. 2011C-3493 13700487 YP_006777540.1 CDS O3K_04050 NC_018658.1 828892 830034 D putative DNA-binding transcriptional regulator 828892..830034 Escherichia coli O104:H4 str. 2011C-3493 13700488 YP_006777541.1 CDS O3K_04055 NC_018658.1 830041 830805 R COG2186 Transcriptional regulators; DNA-binding transcriptional regulator GlcC complement(830041..830805) Escherichia coli O104:H4 str. 2011C-3493 13700489 YP_006777542.1 CDS O3K_04060 NC_018658.1 831056 832555 D COG0277 FAD/FMN-containing dehydrogenases; glycolate oxidase subunit GlcD 831056..832555 Escherichia coli O104:H4 str. 2011C-3493 13700490 YP_006777543.1 CDS glcE NC_018658.1 832555 833607 D COG0277 FAD/FMN-containing dehydrogenases; glycolate oxidase FAD binding subunit 832555..833607 Escherichia coli O104:H4 str. 2011C-3493 13700491 YP_006777544.1 CDS glcF NC_018658.1 833618 834841 D COG0247 Fe-S oxidoreductase; glycolate oxidase iron-sulfur subunit 833618..834841 Escherichia coli O104:H4 str. 2011C-3493 13700492 YP_006777545.1 CDS O3K_04075 NC_018658.1 834846 835250 D COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol; hypothetical protein 834846..835250 Escherichia coli O104:H4 str. 2011C-3493 13700493 YP_006777546.1 CDS O3K_04080 NC_018658.1 835272 837443 D COG2225 Malate synthase; malate synthase G 835272..837443 Escherichia coli O104:H4 str. 2011C-3493 13700494 YP_006777547.1 CDS O3K_04085 NC_018658.1 837799 839481 D COG1620 L-lactate permease; glycolate transporter 837799..839481 Escherichia coli O104:H4 str. 2011C-3493 13700495 YP_006777548.1 CDS O3K_04090 NC_018658.1 839607 839816 R hypothetical protein complement(839607..839816) Escherichia coli O104:H4 str. 2011C-3493 13700496 YP_006777549.1 CDS O3K_04095 NC_018658.1 840099 844532 D inner membrane lipoprotein 840099..844532 Escherichia coli O104:H4 str. 2011C-3493 13700497 YP_006777550.1 CDS O3K_04100 NC_018658.1 844672 845481 D COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; bifunctional prepilin leader peptidase/methylase 844672..845481 Escherichia coli O104:H4 str. 2011C-3493 13700498 YP_006777551.1 CDS O3K_04105 NC_018658.1 845547 845957 D hypothetical protein 845547..845957 Escherichia coli O104:H4 str. 2011C-3493 13700499 YP_006777552.1 CDS O3K_04110 NC_018658.1 845975 846934 D COG3031 Type II secretory pathway, component PulC; putative type II secretion protein GspC 845975..846934 Escherichia coli O104:H4 str. 2011C-3493 13700500 YP_006777553.1 CDS O3K_04115 NC_018658.1 846964 849024 D COG1450 Type II secretory pathway, component PulD; general secretion pathway protein D 846964..849024 Escherichia coli O104:H4 str. 2011C-3493 13700501 YP_006777554.1 CDS O3K_04120 NC_018658.1 849024 850517 D COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; general secretion pathway protein E 849024..850517 Escherichia coli O104:H4 str. 2011C-3493 13700502 YP_006777555.1 CDS O3K_04125 NC_018658.1 850517 851740 D COG1459 Type II secretory pathway, component PulF; General secretion pathway protein F 850517..851740 Escherichia coli O104:H4 str. 2011C-3493 13700503 YP_006777556.1 CDS O3K_04130 NC_018658.1 851757 852212 D COG2165 Type II secretory pathway, pseudopilin PulG; putative general secretion pathway protein G precursor 851757..852212 Escherichia coli O104:H4 str. 2011C-3493 13700504 YP_006777557.1 CDS O3K_04135 NC_018658.1 852216 852779 D COG2165 Type II secretory pathway, pseudopilin PulG; general secretion pathway protein H 852216..852779 Escherichia coli O104:H4 str. 2011C-3493 13700505 YP_006777558.1 CDS O3K_04140 NC_018658.1 852776 853147 D COG2165 Type II secretory pathway, pseudopilin PulG; putative type II secretion protein 852776..853147 Escherichia coli O104:H4 str. 2011C-3493 13700506 YP_006777559.1 CDS O3K_04145 NC_018658.1 853144 853743 D COG4795 Type II secretory pathway, component PulJ; general secretion pathway protein J 853144..853743 Escherichia coli O104:H4 str. 2011C-3493 13700507 YP_006777560.1 CDS O3K_04150 NC_018658.1 853746 854723 D COG3156 Type II secretory pathway, component PulK; type II secretion protein (GspK-like) 853746..854723 Escherichia coli O104:H4 str. 2011C-3493 13700508 YP_006777561.1 CDS O3K_04155 NC_018658.1 854720 855898 D COG3297 Type II secretory pathway, component PulL; GspL-like protein 854720..855898 Escherichia coli O104:H4 str. 2011C-3493 13700509 YP_006777562.1 CDS O3K_04160 NC_018658.1 855900 856436 D COG3149 Type II secretory pathway, component PulM; putative general secretion pathway protein YghD 855900..856436 Escherichia coli O104:H4 str. 2011C-3493 13700510 YP_006777563.1 CDS O3K_04165 NC_018658.1 856717 857559 R hypothetical protein complement(856717..857559) Escherichia coli O104:H4 str. 2011C-3493 13700511 YP_006777564.1 CDS O3K_04170 NC_018658.1 857644 858066 R hypothetical protein complement(857644..858066) Escherichia coli O104:H4 str. 2011C-3493 13700512 YP_006777565.1 CDS O3K_04175 NC_018658.1 858063 858440 R toxin of the YeeV-YeeU toxin-antitoxin system complement(858063..858440) Escherichia coli O104:H4 str. 2011C-3493 13700513 YP_006777566.1 CDS O3K_04180 NC_018658.1 858487 858864 R antitoxin of the YeeV-YeeU toxin-antitoxin system, CP4-44 prophage complement(858487..858864) Escherichia coli O104:H4 str. 2011C-3493 13700514 YP_006777567.1 CDS O3K_04185 NC_018658.1 858944 859165 R hypothetical protein complement(858944..859165) Escherichia coli O104:H4 str. 2011C-3493 13700515 YP_006777568.1 CDS O3K_04190 NC_018658.1 859252 859728 R COG2003 DNA repair proteins; putative DNA repair protein, CP4-44 prophage complement(859252..859728) Escherichia coli O104:H4 str. 2011C-3493 13700516 YP_006777569.1 CDS O3K_04195 NC_018658.1 859744 860217 R hypothetical protein complement(859744..860217) Escherichia coli O104:H4 str. 2011C-3493 13700517 YP_006777570.1 CDS O3K_04200 NC_018658.1 860518 861336 R hypothetical protein complement(860518..861336) Escherichia coli O104:H4 str. 2011C-3493 13700518 YP_006777571.1 CDS O3K_04205 NC_018658.1 861436 861669 R hypothetical protein complement(861436..861669) Escherichia coli O104:H4 str. 2011C-3493 13700519 YP_006777572.1 CDS O3K_04210 NC_018658.1 861748 862203 R hypothetical protein complement(861748..862203) Escherichia coli O104:H4 str. 2011C-3493 13700520 YP_006777573.1 CDS O3K_04215 NC_018658.1 862279 864795 R membrane protein, yeeR complement(862279..864795) Escherichia coli O104:H4 str. 2011C-3493 13700521 YP_006777574.1 CDS O3K_04220 NC_018658.1 864916 868035 R COG2931 RTX toxins and related Ca2+-binding proteins; antigen 43 (Ag43) phase-variable biofilm formation autotransporter, CP4-44 prophage complement(864916..868035) Escherichia coli O104:H4 str. 2011C-3493 13700522 YP_006777575.1 CDS O3K_04225 NC_018658.1 868369 869241 R COG3596 Predicted GTPase; GTPase complement(868369..869241) Escherichia coli O104:H4 str. 2011C-3493 13700523 YP_006777576.1 CDS O3K_04230 NC_018658.1 869351 870370 R hypothetical protein complement(869351..870370) Escherichia coli O104:H4 str. 2011C-3493 13700524 YP_006777577.1 CDS O3K_04235 NC_018658.1 871865 872437 R hypothetical protein complement(871865..872437) Escherichia coli O104:H4 str. 2011C-3493 13700525 YP_006777578.1 CDS O3K_04240 NC_018658.1 872523 872729 R COG3311 Predicted transcriptional regulator; putative Prophage CP4-57 regulatory protein complement(872523..872729) Escherichia coli O104:H4 str. 2011C-3493 13700526 YP_006777579.1 CDS O3K_04245 NC_018658.1 873428 873640 D hemolysin expression-modulating protein 873428..873640 Escherichia coli O104:H4 str. 2011C-3493 13700527 YP_006777580.1 CDS O3K_04250 NC_018658.1 874257 874826 D hypothetical protein 874257..874826 Escherichia coli O104:H4 str. 2011C-3493 13700528 YP_006777581.1 CDS O3K_04255 NC_018658.1 874994 875377 D hypothetical protein 874994..875377 Escherichia coli O104:H4 str. 2011C-3493 13700529 YP_006777582.1 CDS O3K_04260 NC_018658.1 875367 875786 D hypothetical protein 875367..875786 Escherichia coli O104:H4 str. 2011C-3493 13700530 YP_006777583.1 CDS O3K_04265 NC_018658.1 875792 875974 D hypothetical protein 875792..875974 Escherichia coli O104:H4 str. 2011C-3493 13700531 YP_006777584.1 CDS O3K_04270 NC_018658.1 876095 876718 D hypothetical protein 876095..876718 Escherichia coli O104:H4 str. 2011C-3493 13700532 YP_006777585.1 CDS O3K_04275 NC_018658.1 876814 877047 D hypothetical protein 876814..877047 Escherichia coli O104:H4 str. 2011C-3493 13700533 YP_006777586.1 CDS O3K_04280 NC_018658.1 877100 877291 R hypothetical protein complement(877100..877291) Escherichia coli O104:H4 str. 2011C-3493 13700534 YP_006777587.1 CDS O3K_04285 NC_018658.1 877798 878295 D COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 877798..878295 Escherichia coli O104:H4 str. 2011C-3493 13700535 YP_006777588.1 CDS O3K_04290 NC_018658.1 878317 879678 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 878317..879678 Escherichia coli O104:H4 str. 2011C-3493 13700536 YP_006777589.1 CDS O3K_04295 NC_018658.1 879780 881024 D hypothetical protein 879780..881024 Escherichia coli O104:H4 str. 2011C-3493 13700537 YP_006777590.1 CDS O3K_04300 NC_018658.1 881341 883005 D COG0210 Superfamily I DNA and RNA helicases; UvrD/REP helicase 881341..883005 Escherichia coli O104:H4 str. 2011C-3493 13700538 YP_006777591.1 CDS O3K_04305 NC_018658.1 883067 883375 D hypothetical protein 883067..883375 Escherichia coli O104:H4 str. 2011C-3493 13700539 YP_006777592.1 CDS O3K_04310 NC_018658.1 883430 883657 D COG1475 Predicted transcriptional regulators; transcriptional regulator IbrB 883430..883657 Escherichia coli O104:H4 str. 2011C-3493 13700540 YP_006777593.1 CDS O3K_04315 NC_018658.1 883736 884005 D transcriptional regulator 883736..884005 Escherichia coli O104:H4 str. 2011C-3493 13700541 YP_006777594.1 CDS O3K_04320 NC_018658.1 884026 884670 D hypothetical protein 884026..884670 Escherichia coli O104:H4 str. 2011C-3493 13700542 YP_006777595.1 CDS O3K_04325 NC_018658.1 884736 885059 D hypothetical protein 884736..885059 Escherichia coli O104:H4 str. 2011C-3493 13700543 YP_006777596.1 CDS O3K_04330 NC_018658.1 885113 885508 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(885113..885508) Escherichia coli O104:H4 str. 2011C-3493 13700544 YP_006777597.1 CDS O3K_04340 NC_018658.1 885942 886265 D hypothetical protein 885942..886265 Escherichia coli O104:H4 str. 2011C-3493 13700545 YP_006777598.1 CDS O3K_04355 NC_018658.1 887786 888262 D COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 887786..888262 Escherichia coli O104:H4 str. 2011C-3493 13700546 YP_006777599.1 CDS O3K_04360 NC_018658.1 888265 889743 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 888265..889743 Escherichia coli O104:H4 str. 2011C-3493 13700547 YP_006777600.1 CDS O3K_04365 NC_018658.1 889765 890259 D hypothetical protein 889765..890259 Escherichia coli O104:H4 str. 2011C-3493 13700548 YP_006777601.1 CDS O3K_04370 NC_018658.1 890269 890691 D hypothetical protein 890269..890691 Escherichia coli O104:H4 str. 2011C-3493 13700549 YP_006777602.1 CDS O3K_04375 NC_018658.1 890727 891023 R hypothetical protein complement(890727..891023) Escherichia coli O104:H4 str. 2011C-3493 13700550 YP_006777603.1 CDS O3K_04380 NC_018658.1 891155 892486 D COG3519 Uncharacterized protein conserved in bacteria; hypothetical protein 891155..892486 Escherichia coli O104:H4 str. 2011C-3493 13700551 YP_006777604.1 CDS O3K_04385 NC_018658.1 892477 893409 D COG3520 Uncharacterized protein conserved in bacteria; hypothetical protein 892477..893409 Escherichia coli O104:H4 str. 2011C-3493 13700552 YP_006777605.1 CDS O3K_04390 NC_018658.1 893422 895404 D COG3501 Uncharacterized protein conserved in bacteria; hypothetical protein 893422..895404 Escherichia coli O104:H4 str. 2011C-3493 13700553 YP_006777606.1 CDS O3K_04395 NC_018658.1 895415 895882 D hypothetical protein 895415..895882 Escherichia coli O104:H4 str. 2011C-3493 13700554 YP_006777607.1 CDS O3K_04400 NC_018658.1 895886 896191 D COG4104 Uncharacterized conserved protein; hypothetical protein 895886..896191 Escherichia coli O104:H4 str. 2011C-3493 13700555 YP_006777608.1 CDS O3K_04405 NC_018658.1 896195 897271 D COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 896195..897271 Escherichia coli O104:H4 str. 2011C-3493 13700556 YP_006777609.1 CDS O3K_04410 NC_018658.1 897279 897830 D hypothetical protein 897279..897830 Escherichia coli O104:H4 str. 2011C-3493 13700557 YP_006777610.1 CDS O3K_04415 NC_018658.1 897849 899261 D COG3522 Uncharacterized protein conserved in bacteria; hypothetical protein 897849..899261 Escherichia coli O104:H4 str. 2011C-3493 13700558 YP_006777611.1 CDS O3K_04420 NC_018658.1 899289 899603 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; hypothetical protein 899289..899603 Escherichia coli O104:H4 str. 2011C-3493 13700559 YP_006777612.1 CDS O3K_04425 NC_018658.1 899600 900190 D COG3455 Uncharacterized protein conserved in bacteria; hypothetical protein 899600..900190 Escherichia coli O104:H4 str. 2011C-3493 13700560 YP_006777613.1 CDS O3K_04430 NC_018658.1 900187 903600 D COG3523 Uncharacterized protein conserved in bacteria; hypothetical protein 900187..903600 Escherichia coli O104:H4 str. 2011C-3493 13700561 YP_006777614.1 CDS O3K_04435 NC_018658.1 903604 906153 D COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 903604..906153 Escherichia coli O104:H4 str. 2011C-3493 13700562 YP_006777615.1 CDS O3K_04455 NC_018658.1 909444 909830 D COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase 909444..909830 Escherichia coli O104:H4 str. 2011C-3493 13700563 YP_006777616.1 CDS O3K_04460 NC_018658.1 911588 912154 D hypothetical protein 911588..912154 Escherichia coli O104:H4 str. 2011C-3493 13700564 YP_006777617.1 CDS O3K_04465 NC_018658.1 912299 912532 R hypothetical protein complement(912299..912532) Escherichia coli O104:H4 str. 2011C-3493 13700565 YP_006777618.1 CDS O3K_04470 NC_018658.1 912633 913787 D hypothetical protein 912633..913787 Escherichia coli O104:H4 str. 2011C-3493 13700566 YP_006777619.1 CDS O3K_04475 NC_018658.1 914178 914579 D hypothetical protein 914178..914579 Escherichia coli O104:H4 str. 2011C-3493 13700567 YP_006777620.1 CDS O3K_04480 NC_018658.1 914853 915038 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(914853..915038) Escherichia coli O104:H4 str. 2011C-3493 13700568 YP_006777621.1 CDS O3K_04495 NC_018658.1 916373 916636 D COG2801 Transposase and inactivated derivatives; IS150 ORF B; transposase 916373..916636 Escherichia coli O104:H4 str. 2011C-3493 13700569 YP_006777622.1 CDS O3K_04500 NC_018658.1 916969 917367 R COG3436 Transposase and inactivated derivatives; transposase complement(916969..917367) Escherichia coli O104:H4 str. 2011C-3493 13700570 YP_006777623.1 CDS O3K_04505 NC_018658.1 917432 918556 R COG4584 Transposase and inactivated derivatives; transposase complement(917432..918556) Escherichia coli O104:H4 str. 2011C-3493 13700571 YP_006777624.1 CDS O3K_04510 NC_018658.1 918777 919286 D COG3436 Transposase and inactivated derivatives; hypothetical protein 918777..919286 Escherichia coli O104:H4 str. 2011C-3493 13700572 YP_006777625.1 CDS O3K_04515 NC_018658.1 919349 919567 D COG3328 Transposase and inactivated derivatives; transposase 919349..919567 Escherichia coli O104:H4 str. 2011C-3493 13700573 YP_006777626.1 CDS O3K_04520 NC_018658.1 919718 923836 R COG3468 Type V secretory pathway, adhesin AidA; Serine protease pic precursor (ShMu) complement(919718..923836) Escherichia coli O104:H4 str. 2011C-3493 13700574 YP_006777627.1 CDS O3K_04525 NC_018658.1 924001 924387 R COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase complement(924001..924387) Escherichia coli O104:H4 str. 2011C-3493 13700575 YP_006777628.1 CDS O3K_04540 NC_018658.1 926678 926917 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(926678..926917) Escherichia coli O104:H4 str. 2011C-3493 13700576 YP_006777629.1 CDS O3K_04545 NC_018658.1 927234 928385 D COG2826 Transposase and inactivated derivatives, IS30 family; transposase for IS30 927234..928385 Escherichia coli O104:H4 str. 2011C-3493 13700577 YP_006777630.1 CDS O3K_04550 NC_018658.1 928305 928691 R COG2963 Transposase and inactivated derivatives; IS3 family protein; transposase ORF A, IS3 family protein complement(928305..928691) Escherichia coli O104:H4 str. 2011C-3493 13700578 YP_006777631.1 CDS O3K_04555 NC_018658.1 928725 929018 R hypothetical protein complement(928725..929018) Escherichia coli O104:H4 str. 2011C-3493 13700579 YP_006777632.1 CDS O3K_04560 NC_018658.1 929107 931977 R COG3421 Uncharacterized protein conserved in bacteria; PstII restriction-modification enzyme Res subunit complement(929107..931977) Escherichia coli O104:H4 str. 2011C-3493 13700580 YP_006777633.1 CDS O3K_04565 NC_018658.1 931980 933608 R COG2189 Adenine specific DNA methylase Mod; DNA methylase N-4/N-6 complement(931980..933608) Escherichia coli O104:H4 str. 2011C-3493 13700581 YP_006777634.1 CDS O3K_04570 NC_018658.1 933618 936005 R COG1404 Subtilisin-like serine proteases; serine protease complement(933618..936005) Escherichia coli O104:H4 str. 2011C-3493 13700582 YP_006777635.1 CDS O3K_04575 NC_018658.1 936015 936995 R COG0464 ATPases of the AAA+ class; ATPase complement(936015..936995) Escherichia coli O104:H4 str. 2011C-3493 13700583 YP_006777636.1 CDS O3K_04580 NC_018658.1 937021 939870 R COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Helicase complement(937021..939870) Escherichia coli O104:H4 str. 2011C-3493 13700584 YP_006777637.1 CDS O3K_04585 NC_018658.1 940171 940353 D hypothetical protein 940171..940353 Escherichia coli O104:H4 str. 2011C-3493 13700585 YP_006777638.1 CDS O3K_04590 NC_018658.1 940281 940874 D hypothetical protein 940281..940874 Escherichia coli O104:H4 str. 2011C-3493 13700586 YP_006777639.1 CDS O3K_04595 NC_018658.1 941340 941603 R hypothetical protein complement(941340..941603) Escherichia coli O104:H4 str. 2011C-3493 13700587 YP_006777640.1 CDS O3K_04600 NC_018658.1 941744 942247 R COG1662 Transposase and inactivated derivatives, IS1 family; putative IS1 transposase InsAB' complement(941744..942247) Escherichia coli O104:H4 str. 2011C-3493 13700588 YP_006777641.1 CDS O3K_04605 NC_018658.1 942166 942441 R COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA complement(942166..942441) Escherichia coli O104:H4 str. 2011C-3493 13700589 YP_006777642.1 CDS O3K_04610 NC_018658.1 942854 944116 R COG0582 Integrase; Prophage integrase complement(942854..944116) Escherichia coli O104:H4 str. 2011C-3493 13700590 YP_006777643.1 CDS O3K_04615 NC_018658.1 944495 945202 R COG1811 Uncharacterized membrane protein, possible Na+ channel or pump; hypothetical protein complement(944495..945202) Escherichia coli O104:H4 str. 2011C-3493 13700592 YP_006777644.1 CDS O3K_04620 NC_018658.1 945600 947735 D COG1982 Arginine/lysine/ornithine decarboxylases; ornithine decarboxylase 945600..947735 Escherichia coli O104:H4 str. 2011C-3493 13700593 YP_006777645.1 CDS O3K_04625 NC_018658.1 947785 949041 R COG0477 Permeases of the major facilitator superfamily; nucleoside transport, permease complement(947785..949041) Escherichia coli O104:H4 str. 2011C-3493 13700594 YP_006777646.1 CDS mltC NC_018658.1 949243 950322 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); murein transglycosylase C complement(949243..950322) Escherichia coli O104:H4 str. 2011C-3493 13700595 YP_006777647.1 CDS O3K_04635 NC_018658.1 950387 950662 R COG2924 Fe-S cluster protector protein; oxidative damage protection protein complement(950387..950662) Escherichia coli O104:H4 str. 2011C-3493 13700596 YP_006777648.1 CDS O3K_04640 NC_018658.1 950690 951742 R COG1194 A/G-specific DNA glycosylase; adenine DNA glycosylase complement(950690..951742) Escherichia coli O104:H4 str. 2011C-3493 13700597 YP_006777649.1 CDS trmB NC_018658.1 951903 952622 D COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; tRNA (guanine-N(7)-)-methyltransferase 951903..952622 Escherichia coli O104:H4 str. 2011C-3493 13700598 YP_006777650.1 CDS O3K_04650 NC_018658.1 952622 952948 D COG3171 Uncharacterized protein conserved in bacteria; hypothetical protein 952622..952948 Escherichia coli O104:H4 str. 2011C-3493 13700599 YP_006777651.1 CDS O3K_04655 NC_018658.1 952971 953111 D hypothetical protein 952971..953111 Escherichia coli O104:H4 str. 2011C-3493 13700600 YP_006777652.1 CDS O3K_04660 NC_018658.1 953132 953851 D hypothetical protein 953132..953851 Escherichia coli O104:H4 str. 2011C-3493 13700601 YP_006777653.1 CDS ansB NC_018658.1 954027 955073 D COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; L-asparaginase II 954027..955073 Escherichia coli O104:H4 str. 2011C-3493 13700602 YP_006777654.1 CDS O3K_04670 NC_018658.1 955190 956197 D hypothetical protein 955190..956197 Escherichia coli O104:H4 str. 2011C-3493 13700603 YP_006777655.1 CDS O3K_04675 NC_018658.1 956352 957488 R COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; HemN family oxidoreductase complement(956352..957488) Escherichia coli O104:H4 str. 2011C-3493 13700604 YP_006777656.1 CDS O3K_04680 NC_018658.1 957481 958074 R COG0127 Xanthosine triphosphate pyrophosphatase; dITP/XTP pyrophosphatase complement(957481..958074) Escherichia coli O104:H4 str. 2011C-3493 13700605 YP_006777657.1 CDS O3K_04685 NC_018658.1 958082 958372 R COG1872 Uncharacterized conserved protein; hypothetical protein complement(958082..958372) Escherichia coli O104:H4 str. 2011C-3493 13700606 YP_006777658.1 CDS O3K_04690 NC_018658.1 958369 958935 R COG0762 Predicted integral membrane protein; hypothetical protein complement(958369..958935) Escherichia coli O104:H4 str. 2011C-3493 13700607 YP_006777659.1 CDS O3K_04695 NC_018658.1 958953 959657 R COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein complement(958953..959657) Escherichia coli O104:H4 str. 2011C-3493 13700608 YP_006777660.1 CDS O3K_04700 NC_018658.1 959675 960655 D COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT; transporter 959675..960655 Escherichia coli O104:H4 str. 2011C-3493 13700609 YP_006777661.1 CDS O3K_04705 NC_018658.1 960831 961247 R COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); Holliday junction resolvase-like protein complement(960831..961247) Escherichia coli O104:H4 str. 2011C-3493 13700610 YP_006777662.1 CDS O3K_04710 NC_018658.1 961247 961810 R COG1678 Putative transcriptional regulator; hypothetical protein complement(961247..961810) Escherichia coli O104:H4 str. 2011C-3493 13700611 YP_006777663.1 CDS O3K_04715 NC_018658.1 961919 962869 R COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); glutathione synthetase complement(961919..962869) Escherichia coli O104:H4 str. 2011C-3493 13700612 YP_006777664.1 CDS O3K_04720 NC_018658.1 962882 963613 R COG1385 Uncharacterized protein conserved in bacteria; 16S ribosomal RNA methyltransferase RsmE complement(962882..963613) Escherichia coli O104:H4 str. 2011C-3493 13700613 YP_006777665.1 CDS O3K_04725 NC_018658.1 963693 964400 R COG2356 Endonuclease I; DNA-specific endonuclease I complement(963693..964400) Escherichia coli O104:H4 str. 2011C-3493 13700614 YP_006777666.1 CDS O3K_04730 NC_018658.1 964495 964992 R COG3091 Uncharacterized protein conserved in bacteria; hypothetical protein complement(964495..964992) Escherichia coli O104:H4 str. 2011C-3493 13700615 YP_006777667.1 CDS O3K_04735 NC_018658.1 965069 966463 R COG0477 Permeases of the major facilitator superfamily; D-galactose transporter GalP complement(965069..966463) Escherichia coli O104:H4 str. 2011C-3493 13700616 YP_006777668.1 CDS O3K_04740 NC_018658.1 966899 968053 R COG0192 S-adenosylmethionine synthetase; S-adenosylmethionine synthetase complement(966899..968053) Escherichia coli O104:H4 str. 2011C-3493 13700617 YP_006777669.1 CDS O3K_04745 NC_018658.1 968109 968360 D hypothetical protein 968109..968360 Escherichia coli O104:H4 str. 2011C-3493 13700618 YP_006777670.1 CDS O3K_04750 NC_018658.1 968693 968839 D hypothetical protein 968693..968839 Escherichia coli O104:H4 str. 2011C-3493 13700619 YP_006777671.1 CDS O3K_04755 NC_018658.1 968848 970824 D COG1166 Arginine decarboxylase (spermidine biosynthesis); arginine decarboxylase 968848..970824 Escherichia coli O104:H4 str. 2011C-3493 13700620 YP_006777672.1 CDS O3K_04760 NC_018658.1 970970 971701 D hypothetical protein 970970..971701 Escherichia coli O104:H4 str. 2011C-3493 13700621 YP_006777673.1 CDS O3K_04765 NC_018658.1 971837 972757 D COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; agmatinase 971837..972757 Escherichia coli O104:H4 str. 2011C-3493 13700622 YP_006777674.1 CDS O3K_04770 NC_018658.1 972963 973721 R COG0501 Zn-dependent protease with chaperone function; peptidase complement(972963..973721) Escherichia coli O104:H4 str. 2011C-3493 13700623 YP_006777675.1 CDS O3K_04775 NC_018658.1 973999 975990 D COG0021 Transketolase; transketolase 973999..975990 Escherichia coli O104:H4 str. 2011C-3493 13700624 YP_006777676.1 CDS cmtB NC_018658.1 976304 976747 D COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol-specific transporter subunit IIA 976304..976747 Escherichia coli O104:H4 str. 2011C-3493 13700625 YP_006777677.1 CDS O3K_04785 NC_018658.1 976775 978163 D COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system mannitol-specific transporter subunit IIBC 976775..978163 Escherichia coli O104:H4 str. 2011C-3493 13700626 YP_006777678.1 CDS O3K_04790 NC_018658.1 978178 979455 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; putative dehydrogenase 978178..979455 Escherichia coli O104:H4 str. 2011C-3493 13700627 YP_006777679.1 CDS O3K_04795 NC_018658.1 979452 980417 D COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; fructose-1,6-bisphosphatase II-like protein 979452..980417 Escherichia coli O104:H4 str. 2011C-3493 13700628 YP_006777680.1 CDS O3K_04800 NC_018658.1 980439 980948 D COG3722 Transcriptional regulator; putative DNA-binding transcriptional regulator 980439..980948 Escherichia coli O104:H4 str. 2011C-3493 13700629 YP_006777681.1 CDS O3K_04805 NC_018658.1 980945 981658 D COG1072 Panthothenate kinase; nucleoside triphosphate hydrolase domain-containing protein 980945..981658 Escherichia coli O104:H4 str. 2011C-3493 13700630 YP_006777682.1 CDS O3K_04810 NC_018658.1 981630 982307 R COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; ABC transporter ATP-binding protein complement(981630..982307) Escherichia coli O104:H4 str. 2011C-3493 13700631 YP_006777683.1 CDS O3K_04815 NC_018658.1 982301 982978 R COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein complement(982301..982978) Escherichia coli O104:H4 str. 2011C-3493 13700632 YP_006777684.1 CDS O3K_04820 NC_018658.1 982966 983673 R COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; lipoprotein complement(982966..983673) Escherichia coli O104:H4 str. 2011C-3493 13700633 YP_006777685.1 CDS O3K_04825 NC_018658.1 983674 984252 R transporter complement(983674..984252) Escherichia coli O104:H4 str. 2011C-3493 13700634 YP_006777686.1 CDS O3K_04830 NC_018658.1 984275 984706 R COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif; DNA-binding protein complement(984275..984706) Escherichia coli O104:H4 str. 2011C-3493 13700635 YP_006777687.1 CDS O3K_04835 NC_018658.1 985078 986097 D COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; erythrose 4-phosphate dehydrogenase 985078..986097 Escherichia coli O104:H4 str. 2011C-3493 13700636 YP_006777688.1 CDS pgk NC_018658.1 986147 987310 D COG0126 3-phosphoglycerate kinase; phosphoglycerate kinase 986147..987310 Escherichia coli O104:H4 str. 2011C-3493 13700637 YP_006777689.1 CDS O3K_04845 NC_018658.1 987525 988604 D COG0191 Fructose/tagatose bisphosphate aldolase; fructose-bisphosphate aldolase 987525..988604 Escherichia coli O104:H4 str. 2011C-3493 13700638 YP_006777690.1 CDS O3K_04850 NC_018658.1 988962 989822 D COG0668 Small-conductance mechanosensitive channel; mechanosensitive channel MscS 988962..989822 Escherichia coli O104:H4 str. 2011C-3493 13700639 YP_006777691.1 CDS O3K_04855 NC_018658.1 989961 990596 D COG1279 Lysine efflux permease; arginine exporter protein 989961..990596 Escherichia coli O104:H4 str. 2011C-3493 13700640 YP_006777692.1 CDS O3K_04860 NC_018658.1 990689 991429 D COG2968 Uncharacterized conserved protein; oxidative stress defense protein 990689..991429 Escherichia coli O104:H4 str. 2011C-3493 13700641 YP_006777693.1 CDS O3K_04865 NC_018658.1 991596 992492 D COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator 991596..992492 Escherichia coli O104:H4 str. 2011C-3493 13700642 YP_006777694.1 CDS O3K_04870 NC_018658.1 992489 993967 R COG0427 Acetyl-CoA hydrolase; acetyl-CoA hydrolase complement(992489..993967) Escherichia coli O104:H4 str. 2011C-3493 13700643 YP_006777695.1 CDS O3K_04875 NC_018658.1 993991 994776 R COG1024 Enoyl-CoA hydratase/carnithine racemase; methylmalonyl-CoA decarboxylase complement(993991..994776) Escherichia coli O104:H4 str. 2011C-3493 13700644 YP_006777696.1 CDS O3K_04880 NC_018658.1 994787 995782 R COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family; membrane ATPase/protein kinase complement(994787..995782) Escherichia coli O104:H4 str. 2011C-3493 13700645 YP_006777697.1 CDS O3K_04885 NC_018658.1 995775 997067 R COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; methylmalonyl-CoA mutase complement(995775..997067) Escherichia coli O104:H4 str. 2011C-3493 13700646 YP_006777698.1 CDS O3K_04890 NC_018658.1 997191 997919 R COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; methylmalonyl-CoA mutase complement(997191..997919) Escherichia coli O104:H4 str. 2011C-3493 13700647 YP_006777699.1 CDS O3K_04895 NC_018658.1 998123 999016 R COG0583 Transcriptional regulator; chromosome replication initiation inhibitor protein complement(998123..999016) Escherichia coli O104:H4 str. 2011C-3493 13700648 YP_006777700.1 CDS O3K_04900 NC_018658.1 999399 1000058 D COG0120 Ribose 5-phosphate isomerase; ribose-5-phosphate isomerase A 999399..1000058 Escherichia coli O104:H4 str. 2011C-3493 13700649 YP_006777701.1 CDS O3K_04905 NC_018658.1 1000314 1001546 D COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; D-3-phosphoglycerate dehydrogenase 1000314..1001546 Escherichia coli O104:H4 str. 2011C-3493 13700650 YP_006777702.1 CDS O3K_04910 NC_018658.1 1002327 1002875 R COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase complement(1002327..1002875) Escherichia coli O104:H4 str. 2011C-3493 13700651 YP_006777703.1 CDS O3K_04915 NC_018658.1 1003175 1003504 R COG3027 Uncharacterized protein conserved in bacteria; Z-ring-associated protein complement(1003175..1003504) Escherichia coli O104:H4 str. 2011C-3493 13700652 YP_006777704.1 CDS O3K_04920 NC_018658.1 1003672 1004250 D COG3079 Uncharacterized protein conserved in bacteria; hypothetical protein 1003672..1004250 Escherichia coli O104:H4 str. 2011C-3493 13700653 YP_006777705.1 CDS O3K_04925 NC_018658.1 1004276 1005601 D COG0006 Xaa-Pro aminopeptidase; proline aminopeptidase P II 1004276..1005601 Escherichia coli O104:H4 str. 2011C-3493 13700654 YP_006777706.1 CDS O3K_04930 NC_018658.1 1005598 1006776 D COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 2-octaprenyl-6-methoxyphenyl hydroxylase 1005598..1006776 Escherichia coli O104:H4 str. 2011C-3493 13700655 YP_006777707.1 CDS O3K_04935 NC_018658.1 1006799 1008001 D COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; oxidoreductase 1006799..1008001 Escherichia coli O104:H4 str. 2011C-3493 13700656 YP_006777708.1 CDS gcvT NC_018658.1 1008449 1009543 D COG0404 Glycine cleavage system T protein (aminomethyltransferase); glycine cleavage system aminomethyltransferase T 1008449..1009543 Escherichia coli O104:H4 str. 2011C-3493 13700657 YP_006777709.1 CDS O3K_04945 NC_018658.1 1009567 1009956 D COG0509 Glycine cleavage system H protein (lipoate-binding); glycine cleavage system protein H 1009567..1009956 Escherichia coli O104:H4 str. 2011C-3493 13700658 YP_006777710.1 CDS O3K_04950 NC_018658.1 1010075 1012948 D COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; glycine dehydrogenase 1010075..1012948 Escherichia coli O104:H4 str. 2011C-3493 13700659 YP_006777711.1 CDS O3K_04955 NC_018658.1 1013209 1013952 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative NAD(P)-binding oxidoreductase 1013209..1013952 Escherichia coli O104:H4 str. 2011C-3493 13700660 YP_006777712.1 CDS O3K_04960 NC_018658.1 1014009 1015442 R COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; 6-phospho-beta-glucosidase complement(1014009..1015442) Escherichia coli O104:H4 str. 2011C-3493 13700661 YP_006777713.1 CDS O3K_04965 NC_018658.1 1015487 1015798 D COG3097 Uncharacterized protein conserved in bacteria; hypothetical protein 1015487..1015798 Escherichia coli O104:H4 str. 2011C-3493 13700662 YP_006777714.1 CDS O3K_04970 NC_018658.1 1015962 1016621 D COG1272 Predicted membrane protein, hemolysin III homolog; hemolysin 1015962..1016621 Escherichia coli O104:H4 str. 2011C-3493 13700663 YP_006777715.1 CDS O3K_04975 NC_018658.1 1016699 1017679 R COG0354 Predicted aminomethyltransferase related to GcvT; putative global regulator complement(1016699..1017679) Escherichia coli O104:H4 str. 2011C-3493 13700664 YP_006777716.1 CDS O3K_04980 NC_018658.1 1017922 1018188 D COG2938 Uncharacterized conserved protein; hypothetical protein 1017922..1018188 Escherichia coli O104:H4 str. 2011C-3493 13700665 YP_006777717.1 CDS O3K_04985 NC_018658.1 1018169 1018576 D hypothetical protein 1018169..1018576 Escherichia coli O104:H4 str. 2011C-3493 13700666 YP_006777718.1 CDS O3K_04990 NC_018658.1 1018616 1019137 R COG0716 Flavodoxins; flavodoxin FldB complement(1018616..1019137) Escherichia coli O104:H4 str. 2011C-3493 13700667 YP_006777719.1 CDS xerD NC_018658.1 1019249 1020145 D COG4974 Site-specific recombinase XerD; site-specific tyrosine recombinase XerD 1019249..1020145 Escherichia coli O104:H4 str. 2011C-3493 13700668 YP_006777720.1 CDS O3K_05000 NC_018658.1 1020170 1020880 D COG1651 Protein-disulfide isomerase; protein disulfide isomerase II DsbC 1020170..1020880 Escherichia coli O104:H4 str. 2011C-3493 13700669 YP_006777721.1 CDS O3K_05005 NC_018658.1 1020886 1022619 D COG0608 Single-stranded DNA-specific exonuclease; ssDNA exonuclease RecJ 1020886..1022619 Escherichia coli O104:H4 str. 2011C-3493 13700670 YP_006777722.1 CDS prfB NC_018658.1 1022927 1023808 D COG1186 Protein chain release factor B; peptide chain release factor 2 1022927..1023808 Escherichia coli O104:H4 str. 2011C-3493 13700671 YP_006777723.1 CDS lysS NC_018658.1 1023818 1025335 D COG1190 Lysyl-tRNA synthetase (class II); lysyl-tRNA synthetase 1023818..1025335 Escherichia coli O104:H4 str. 2011C-3493 13700672 YP_006777724.1 CDS O3K_05020 NC_018658.1 1025378 1025926 R COG1443 Isopentenyldiphosphate isomerase; isopentenyl-diphosphate delta-isomerase complement(1025378..1025926) Escherichia coli O104:H4 str. 2011C-3493 13700673 YP_006777725.1 CDS O3K_05025 NC_018658.1 1026049 1026174 R hypothetical protein complement(1026049..1026174) Escherichia coli O104:H4 str. 2011C-3493 13700674 YP_006777726.1 CDS O3K_05030 NC_018658.1 1026176 1027624 R COG2233 Xanthine/uracil permeases; transporter complement(1026176..1027624) Escherichia coli O104:H4 str. 2011C-3493 13700675 YP_006777727.1 CDS O3K_05035 NC_018658.1 1028060 1029979 D COG1142 Fe-S-cluster-containing hydrogenase components 2; putative oxidoreductase Fe-S binding subunit 1028060..1029979 Escherichia coli O104:H4 str. 2011C-3493 13700676 YP_006777728.1 CDS O3K_05040 NC_018658.1 1029979 1030467 D COG1142 Fe-S-cluster-containing hydrogenase components 2; oxidoreductase 1029979..1030467 Escherichia coli O104:H4 str. 2011C-3493 13700677 YP_006777729.1 CDS O3K_05045 NC_018658.1 1030503 1031870 R COG2252 Permeases; hypothetical protein complement(1030503..1031870) Escherichia coli O104:H4 str. 2011C-3493 13700678 YP_006777730.1 CDS O3K_05050 NC_018658.1 1031906 1033222 R COG0402 Cytosine deaminase and related metal-dependent hydrolases; guanine deaminase complement(1031906..1033222) Escherichia coli O104:H4 str. 2011C-3493 13700679 YP_006777731.1 CDS O3K_05055 NC_018658.1 1033240 1034640 R COG2233 Xanthine/uracil permeases; transporter complement(1033240..1034640) Escherichia coli O104:H4 str. 2011C-3493 13700680 YP_006777732.1 CDS O3K_05060 NC_018658.1 1034805 1037675 R COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; putative hypoxanthine oxidase complement(1034805..1037675) Escherichia coli O104:H4 str. 2011C-3493 13700681 YP_006777733.1 CDS O3K_05065 NC_018658.1 1037672 1038451 R COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; oxidoreductase complement(1037672..1038451) Escherichia coli O104:H4 str. 2011C-3493 13700682 YP_006777734.1 CDS O3K_05070 NC_018658.1 1038502 1039830 R COG0402 Cytosine deaminase and related metal-dependent hydrolases; putative chlorohydrolase/aminohydrolase complement(1038502..1039830) Escherichia coli O104:H4 str. 2011C-3493 13700683 YP_006777735.1 CDS O3K_05075 NC_018658.1 1039833 1042931 R COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; putative selenate reductase subunit YgfK complement(1039833..1042931) Escherichia coli O104:H4 str. 2011C-3493 13700684 YP_006777736.1 CDS O3K_05080 NC_018658.1 1043253 1043831 R COG2068 Uncharacterized MobA-related protein; hypothetical protein complement(1043253..1043831) Escherichia coli O104:H4 str. 2011C-3493 13700685 YP_006777737.1 CDS O3K_05085 NC_018658.1 1043934 1044704 D COG0769 UDP-N-acetylmuramyl tripeptide synthase; hypothetical protein 1043934..1044704 Escherichia coli O104:H4 str. 2011C-3493 13700686 YP_006777738.1 CDS O3K_05090 NC_018658.1 1044752 1046377 D COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 1044752..1046377 Escherichia coli O104:H4 str. 2011C-3493 13700687 YP_006777739.1 CDS O3K_05095 NC_018658.1 1046418 1047350 R COG0549 Carbamate kinase; putative amino acid kinase complement(1046418..1047350) Escherichia coli O104:H4 str. 2011C-3493 13700688 YP_006777740.1 CDS O3K_05100 NC_018658.1 1047398 1048783 R COG0044 Dihydroorotase and related cyclic amidohydrolases; phenylhydantoinase complement(1047398..1048783) Escherichia coli O104:H4 str. 2011C-3493 13700689 YP_006777741.1 CDS O3K_05105 NC_018658.1 1048836 1050047 R COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; peptidase complement(1048836..1050047) Escherichia coli O104:H4 str. 2011C-3493 13700690 YP_006777742.1 CDS O3K_05110 NC_018658.1 1050105 1051301 R COG1171 Threonine dehydratase; diaminopropionate ammonia-lyase complement(1050105..1051301) Escherichia coli O104:H4 str. 2011C-3493 13700691 YP_006777743.1 CDS O3K_05115 NC_018658.1 1051359 1052546 R COG0078 Ornithine carbamoyltransferase; aspartate/ornithine carbamoyltransferase family protein complement(1051359..1052546) Escherichia coli O104:H4 str. 2011C-3493 13700692 YP_006777744.1 CDS O3K_05120 NC_018658.1 1053025 1054803 D COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains; putative DNA-binding transcriptional regulator 1053025..1054803 Escherichia coli O104:H4 str. 2011C-3493 13700693 YP_006777745.1 CDS O3K_05125 NC_018658.1 1054843 1055322 R COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; xanthine dehydrogenase subunit XdhC complement(1054843..1055322) Escherichia coli O104:H4 str. 2011C-3493 13700694 YP_006777746.1 CDS O3K_05130 NC_018658.1 1055319 1056197 R COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; xanthine dehydrogenase subunit XdhB complement(1055319..1056197) Escherichia coli O104:H4 str. 2011C-3493 13700695 YP_006777747.1 CDS O3K_05135 NC_018658.1 1056208 1058505 R COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; xanthine dehydrogenase subunit XdhA complement(1056208..1058505) Escherichia coli O104:H4 str. 2011C-3493 13700696 YP_006777748.1 CDS O3K_05140 NC_018658.1 1058920 1059675 D COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 1058920..1059675 Escherichia coli O104:H4 str. 2011C-3493 13700697 YP_006777749.1 CDS O3K_05145 NC_018658.1 1060019 1061671 D hypothetical protein 1060019..1061671 Escherichia coli O104:H4 str. 2011C-3493 13700699 YP_006777750.1 CDS spaP NC_018658.1 1062740 1063405 D COG4790 Type III secretory pathway, component EscR; type III secretion system protein SpaP 1062740..1063405 Escherichia coli O104:H4 str. 2011C-3493 13700700 YP_006777751.1 CDS O3K_05165 NC_018658.1 1063415 1063675 D COG4794 Type III secretory pathway, component EscS; type III secretion protein EpaQ 1063415..1063675 Escherichia coli O104:H4 str. 2011C-3493 13700701 YP_006777752.1 CDS O3K_05170 NC_018658.1 1063677 1064444 D COG4791 Type III secretory pathway, component EscT; type III secretion apparatus protein SpaR/YscT/HrcT 1063677..1064444 Escherichia coli O104:H4 str. 2011C-3493 13700702 YP_006777753.1 CDS O3K_05185 NC_018658.1 1065215 1065607 D COG1377 Flagellar biosynthesis pathway, component FlhB; type III secretion system protein SpaS 1065215..1065607 Escherichia coli O104:H4 str. 2011C-3493 13700703 YP_006777754.1 CDS O3K_05190 NC_018658.1 1065669 1065962 R hypothetical protein complement(1065669..1065962) Escherichia coli O104:H4 str. 2011C-3493 13700704 YP_006777755.1 CDS O3K_05195 NC_018658.1 1065964 1066464 R response regulator containing a CheY0like receiver domain and an HTH DNA-binding domain; COG2771 DNA-binding HTH domain-containing proteins; putative type III secretion system regulator complement(1065964..1066464) Escherichia coli O104:H4 str. 2011C-3493 13700705 YP_006777756.1 CDS O3K_05200 NC_018658.1 1066722 1067903 D Type III secretion EprH protein 1066722..1067903 Escherichia coli O104:H4 str. 2011C-3493 13700706 YP_006777757.1 CDS O3K_05205 NC_018658.1 1067917 1068072 D type III secretion protein EprI 1067917..1068072 Escherichia coli O104:H4 str. 2011C-3493 13700707 YP_006777758.1 CDS O3K_05210 NC_018658.1 1068249 1068464 D type III secretion protein EprJ 1068249..1068464 Escherichia coli O104:H4 str. 2011C-3493 13700708 YP_006777759.1 CDS O3K_05215 NC_018658.1 1068505 1069239 D COG4669 Type III secretory pathway, lipoprotein EscJ; type III secretion system lipoprotein EprK 1068505..1069239 Escherichia coli O104:H4 str. 2011C-3493 13700709 YP_006777760.1 CDS O3K_05220 NC_018658.1 1069255 1069836 D hypothetical protein 1069255..1069836 Escherichia coli O104:H4 str. 2011C-3493 13700710 YP_006777761.1 CDS O3K_05225 NC_018658.1 1070053 1070484 D hypothetical protein 1070053..1070484 Escherichia coli O104:H4 str. 2011C-3493 13700711 YP_006777762.1 CDS O3K_05230 NC_018658.1 1070705 1070860 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 1070705..1070860 Escherichia coli O104:H4 str. 2011C-3493 13700712 YP_006777763.1 CDS O3K_05235 NC_018658.1 1070894 1071337 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; hypothetical protein 1070894..1071337 Escherichia coli O104:H4 str. 2011C-3493 13700713 YP_006777764.1 CDS O3K_05240 NC_018658.1 1071382 1071756 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); peptidoglycan-binding-like protein precursor complement(1071382..1071756) Escherichia coli O104:H4 str. 2011C-3493 13700714 YP_006777765.1 CDS O3K_05245 NC_018658.1 1071941 1072159 R hypothetical protein complement(1071941..1072159) Escherichia coli O104:H4 str. 2011C-3493 13700715 YP_006777766.1 CDS O3K_05250 NC_018658.1 1072327 1073703 R COG3710 DNA-binding winged-HTH domains; transcriptional regulator complement(1072327..1073703) Escherichia coli O104:H4 str. 2011C-3493 13700716 YP_006777767.1 CDS O3K_05255 NC_018658.1 1074038 1074529 R COG0457 FOG: TPR repeat; chaperone complement(1074038..1074529) Escherichia coli O104:H4 str. 2011C-3493 13700717 YP_006777768.1 CDS O3K_05260 NC_018658.1 1074807 1075244 R hypothetical protein complement(1074807..1075244) Escherichia coli O104:H4 str. 2011C-3493 13700718 YP_006777769.1 CDS O3K_05265 NC_018658.1 1075899 1075979 D hypothetical protein 1075899..1075979 Escherichia coli O104:H4 str. 2011C-3493 13700719 YP_006777770.1 CDS O3K_05270 NC_018658.1 1076012 1076494 R hypothetical protein complement(1076012..1076494) Escherichia coli O104:H4 str. 2011C-3493 13700720 YP_006777771.1 CDS O3K_05275 NC_018658.1 1076487 1077296 R COG3710 DNA-binding winged-HTH domains; transcriptional regulator complement(1076487..1077296) Escherichia coli O104:H4 str. 2011C-3493 13700721 YP_006777772.1 CDS O3K_05280 NC_018658.1 1077630 1078262 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; yqeH protein complement(1077630..1078262) Escherichia coli O104:H4 str. 2011C-3493 13700722 YP_006777773.1 CDS O3K_05285 NC_018658.1 1078722 1079951 R COG0814 Amino acid permeases; transporter protein complement(1078722..1079951) Escherichia coli O104:H4 str. 2011C-3493 13700723 YP_006777774.1 CDS O3K_05290 NC_018658.1 1080206 1081387 D COG0183 Acetyl-CoA acetyltransferase; putative acyltransferase 1080206..1081387 Escherichia coli O104:H4 str. 2011C-3493 13700724 YP_006777775.1 CDS O3K_05295 NC_018658.1 1081674 1082510 D COG3717 5-keto 4-deoxyuronate isomerase; 5-keto-4-deoxyuronate isomerase 1081674..1082510 Escherichia coli O104:H4 str. 2011C-3493 13700725 YP_006777776.1 CDS O3K_05300 NC_018658.1 1082540 1083301 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2-deoxy-D-gluconate 3-dehydrogenase 1082540..1083301 Escherichia coli O104:H4 str. 2011C-3493 13700726 YP_006777777.1 CDS O3K_05305 NC_018658.1 1083616 1085034 D COG0477 Permeases of the major facilitator superfamily; sugar transporter 1083616..1085034 Escherichia coli O104:H4 str. 2011C-3493 13700727 YP_006777778.1 CDS O3K_05310 NC_018658.1 1085163 1085855 D COG1794 Aspartate racemase; putative racemase 1085163..1085855 Escherichia coli O104:H4 str. 2011C-3493 13700728 YP_006777779.1 CDS O3K_05315 NC_018658.1 1085842 1086777 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator LysR complement(1085842..1086777) Escherichia coli O104:H4 str. 2011C-3493 13700729 YP_006777780.1 CDS O3K_05320 NC_018658.1 1086899 1088161 D COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 1086899..1088161 Escherichia coli O104:H4 str. 2011C-3493 13700730 YP_006777781.1 CDS O3K_05325 NC_018658.1 1088168 1089199 R COG1609 Transcriptional regulators; DNA-binding transcriptional regulator GalR complement(1088168..1089199) Escherichia coli O104:H4 str. 2011C-3493 13700731 YP_006777782.1 CDS O3K_05330 NC_018658.1 1089785 1091944 D COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 1089785..1091944 Escherichia coli O104:H4 str. 2011C-3493 13700732 YP_006777783.1 CDS O3K_05335 NC_018658.1 1091937 1093130 D COG0477 Permeases of the major facilitator superfamily; lysophospholipid transporter LplT 1091937..1093130 Escherichia coli O104:H4 str. 2011C-3493 13700733 YP_006777784.1 CDS tas NC_018658.1 1093162 1094202 R COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); putative aldo-keto reductase complement(1093162..1094202) Escherichia coli O104:H4 str. 2011C-3493 13700734 YP_006777785.1 CDS O3K_05345 NC_018658.1 1094310 1094528 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; hypothetical protein complement(1094310..1094528) Escherichia coli O104:H4 str. 2011C-3493 13700735 YP_006777786.1 CDS O3K_05350 NC_018658.1 1094666 1095379 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein complement(1094666..1095379) Escherichia coli O104:H4 str. 2011C-3493 13700736 YP_006777787.1 CDS O3K_05355 NC_018658.1 1095448 1096137 R COG3066 DNA mismatch repair protein; DNA mismatch repair protein complement(1095448..1096137) Escherichia coli O104:H4 str. 2011C-3493 13700737 YP_006777788.1 CDS O3K_05360 NC_018658.1 1096822 1097352 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; RNA pyrophosphohydrolase 1096822..1097352 Escherichia coli O104:H4 str. 2011C-3493 13700738 YP_006777789.1 CDS O3K_05365 NC_018658.1 1097365 1099611 D fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; COG3605 Signal transduction protein containing GAF and PtsI domains; PtsP 1097365..1099611 Escherichia coli O104:H4 str. 2011C-3493 13700739 YP_006777790.1 CDS O3K_05370 NC_018658.1 1099762 1100637 D COG0682 Prolipoprotein diacylglyceryltransferase; prolipoprotein diacylglyceryl transferase 1099762..1100637 Escherichia coli O104:H4 str. 2011C-3493 13700740 YP_006777791.1 CDS thyA NC_018658.1 1100644 1101438 D COG0207 Thymidylate synthase; thymidylate synthase 1100644..1101438 Escherichia coli O104:H4 str. 2011C-3493 13700741 YP_006777792.1 CDS O3K_05380 NC_018658.1 1101623 1102093 D COG2165 Type II secretory pathway, pseudopilin PulG; hypothetical protein 1101623..1102093 Escherichia coli O104:H4 str. 2011C-3493 13700742 YP_006777793.1 CDS O3K_05385 NC_018658.1 1102084 1102647 D COG4795 Type II secretory pathway, component PulJ; hypothetical protein 1102084..1102647 Escherichia coli O104:H4 str. 2011C-3493 13700743 YP_006777794.1 CDS O3K_05390 NC_018658.1 1102644 1103051 D hypothetical protein 1102644..1103051 Escherichia coli O104:H4 str. 2011C-3493 13700744 YP_006777795.1 CDS O3K_05395 NC_018658.1 1103036 1103359 D hypothetical protein 1103036..1103359 Escherichia coli O104:H4 str. 2011C-3493 13700745 YP_006777796.1 CDS recC NC_018658.1 1103372 1106740 D COG1330 Exonuclease V gamma subunit; exonuclease V subunit gamma 1103372..1106740 Escherichia coli O104:H4 str. 2011C-3493 13700746 YP_006777797.1 CDS O3K_05405 NC_018658.1 1106916 1109804 D COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; protease3 1106916..1109804 Escherichia coli O104:H4 str. 2011C-3493 13700747 YP_006777798.1 CDS recB NC_018658.1 1109797 1113339 D COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); exonuclease V subunit beta 1109797..1113339 Escherichia coli O104:H4 str. 2011C-3493 13700748 YP_006777799.1 CDS recD NC_018658.1 1113339 1115165 D COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; exonuclease V subunit alpha 1113339..1115165 Escherichia coli O104:H4 str. 2011C-3493 13700749 YP_006777800.1 CDS O3K_05420 NC_018658.1 1115227 1116558 R COG0548 Acetylglutamate kinase; N-acetylglutamate synthase complement(1115227..1116558) Escherichia coli O104:H4 str. 2011C-3493 13700750 YP_006777801.1 CDS O3K_05425 NC_018658.1 1116790 1118043 D COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 1116790..1118043 Escherichia coli O104:H4 str. 2011C-3493 13700751 YP_006777802.1 CDS mltA NC_018658.1 1118402 1119499 D COG2821 Membrane-bound lytic murein transglycosylase; murein transglycosylase A 1118402..1119499 Escherichia coli O104:H4 str. 2011C-3493 13700753 YP_006777803.1 CDS O3K_05435 NC_018658.1 1119576 1120382 D COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; sulfur acceptor protein CsdL 1119576..1120382 Escherichia coli O104:H4 str. 2011C-3493 13700754 YP_006777804.1 CDS O3K_05440 NC_018658.1 1120433 1120876 R COG2166 SufE protein probably involved in Fe-S center assembly; CsdA-binding activator complement(1120433..1120876) Escherichia coli O104:H4 str. 2011C-3493 13700755 YP_006777805.1 CDS O3K_05445 NC_018658.1 1120876 1122081 R COG0520 Selenocysteine lyase; cysteine sulfinate desulfinase complement(1120876..1122081) Escherichia coli O104:H4 str. 2011C-3493 13700756 YP_006777806.1 CDS O3K_05450 NC_018658.1 1122273 1122500 D hypothetical protein 1122273..1122500 Escherichia coli O104:H4 str. 2011C-3493 13700757 YP_006777807.1 CDS O3K_05455 NC_018658.1 1122851 1123768 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator GcvA 1122851..1123768 Escherichia coli O104:H4 str. 2011C-3493 13700758 YP_006777808.1 CDS O3K_05460 NC_018658.1 1123787 1124182 D COG2363 Uncharacterized small membrane protein; hypothetical protein 1123787..1124182 Escherichia coli O104:H4 str. 2011C-3493 13700759 YP_006777809.1 CDS O3K_05465 NC_018658.1 1124175 1125275 D COG2933 Predicted SAM-dependent methyltransferase; putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase 1124175..1125275 Escherichia coli O104:H4 str. 2011C-3493 13700760 YP_006777810.1 CDS O3K_05470 NC_018658.1 1125319 1126050 R COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional activator FucR complement(1125319..1126050) Escherichia coli O104:H4 str. 2011C-3493 13700761 YP_006777811.1 CDS fucU NC_018658.1 1126108 1126530 R COG4154 Fucose dissimilation pathway protein FucU; L-fucose mutarotase complement(1126108..1126530) Escherichia coli O104:H4 str. 2011C-3493 13700762 YP_006777812.1 CDS O3K_05480 NC_018658.1 1126532 1127950 R COG1070 Sugar (pentulose and hexulose) kinases; L-fuculokinase complement(1126532..1127950) Escherichia coli O104:H4 str. 2011C-3493 13700763 YP_006777813.1 CDS fucI NC_018658.1 1128059 1129834 R COG2407 L-fucose isomerase and related proteins; L-fucose isomerase complement(1128059..1129834) Escherichia coli O104:H4 str. 2011C-3493 13700764 YP_006777814.1 CDS O3K_05490 NC_018658.1 1129867 1131183 R COG0738 Fucose permease; L-fucose transporter complement(1129867..1131183) Escherichia coli O104:H4 str. 2011C-3493 13700765 YP_006777815.1 CDS O3K_05495 NC_018658.1 1131730 1132377 D COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-fuculose phosphate aldolase 1131730..1132377 Escherichia coli O104:H4 str. 2011C-3493 13700766 YP_006777816.1 CDS O3K_05500 NC_018658.1 1132405 1133553 D COG1454 Alcohol dehydrogenase, class IV; L-1,2-propanediol oxidoreductase 1132405..1133553 Escherichia coli O104:H4 str. 2011C-3493 13700767 YP_006777817.1 CDS O3K_05505 NC_018658.1 1133608 1134453 R COG0258 5'-3' exonuclease (including N-terminal domain of PolI); flap endonuclease-like protein complement(1133608..1134453) Escherichia coli O104:H4 str. 2011C-3493 13700768 YP_006777818.1 CDS O3K_05510 NC_018658.1 1134475 1135842 R COG1760 L-serine deaminase; L-serine deaminase II complement(1134475..1135842) Escherichia coli O104:H4 str. 2011C-3493 13700769 YP_006777819.1 CDS O3K_05515 NC_018658.1 1135900 1137189 R COG0814 Amino acid permeases; serine transporter complement(1135900..1137189) Escherichia coli O104:H4 str. 2011C-3493 13700770 YP_006777820.1 CDS O3K_05520 NC_018658.1 1137746 1139110 R COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein complement(1137746..1139110) Escherichia coli O104:H4 str. 2011C-3493 13700771 YP_006777821.1 CDS queF NC_018658.1 1139222 1140070 R COG2904 Uncharacterized protein conserved in bacteria; 7-cyano-7-deazaguanine reductase complement(1139222..1140070) Escherichia coli O104:H4 str. 2011C-3493 13700772 YP_006777822.1 CDS O3K_05530 NC_018658.1 1140138 1140683 D SecY interacting protein Syd 1140138..1140683 Escherichia coli O104:H4 str. 2011C-3493 13700773 YP_006777823.1 CDS O3K_05535 NC_018658.1 1140918 1141058 D hypothetical protein 1140918..1141058 Escherichia coli O104:H4 str. 2011C-3493 13700774 YP_006777824.1 CDS O3K_05540 NC_018658.1 1141305 1141634 D COG3098 Uncharacterized protein conserved in bacteria; hypothetical protein 1141305..1141634 Escherichia coli O104:H4 str. 2011C-3493 13700775 YP_006777825.1 CDS O3K_05555 NC_018658.1 1142434 1142883 D COG0716 Flavodoxins; flavodoxin 1142434..1142883 Escherichia coli O104:H4 str. 2011C-3493 13700776 YP_006777826.1 CDS O3K_05560 NC_018658.1 1143318 1144670 D COG0477 Permeases of the major facilitator superfamily; putative D-glucarate transporter GudP 1143318..1144670 Escherichia coli O104:H4 str. 2011C-3493 13700777 YP_006777827.1 CDS O3K_05575 NC_018658.1 1146033 1147373 D COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; (D)-glucarate dehydratase 1 1146033..1147373 Escherichia coli O104:H4 str. 2011C-3493 13700778 YP_006777828.1 CDS O3K_05580 NC_018658.1 1147605 1150361 R COG0642 Signal transduction histidine kinase; hybrid sensory histidine kinase BarA complement(1147605..1150361) Escherichia coli O104:H4 str. 2011C-3493 13700779 YP_006777829.1 CDS rumA NC_018658.1 1150418 1151719 D COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; 23S rRNA m(5)U1939 methyltransferase 1150418..1151719 Escherichia coli O104:H4 str. 2011C-3493 13700780 YP_006777830.1 CDS relA NC_018658.1 1151767 1154001 D COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; (p)ppGpp synthetase I 1151767..1154001 Escherichia coli O104:H4 str. 2011C-3493 13700781 YP_006777831.1 CDS O3K_05595 NC_018658.1 1154079 1154327 D COG2336 Growth regulator; antitoxin MazE 1154079..1154327 Escherichia coli O104:H4 str. 2011C-3493 13700782 YP_006777832.1 CDS O3K_05600 NC_018658.1 1154327 1154662 D COG2337 Growth inhibitor; toxin MazF 1154327..1154662 Escherichia coli O104:H4 str. 2011C-3493 13700783 YP_006777833.1 CDS mazG NC_018658.1 1154733 1155524 D COG1694 Predicted pyrophosphatase; nucleoside triphosphate pyrophosphohydrolase 1154733..1155524 Escherichia coli O104:H4 str. 2011C-3493 13700784 YP_006777834.1 CDS pyrG NC_018658.1 1155752 1157389 D COG0504 CTP synthase (UTP-ammonia lyase); CTP synthetase 1155752..1157389 Escherichia coli O104:H4 str. 2011C-3493 13700785 YP_006777835.1 CDS eno NC_018658.1 1157477 1158775 D COG0148 Enolase; enolase 1157477..1158775 Escherichia coli O104:H4 str. 2011C-3493 13700786 YP_006777836.1 CDS O3K_05620 NC_018658.1 1158759 1158911 R hypothetical protein complement(1158759..1158911) Escherichia coli O104:H4 str. 2011C-3493 13700787 YP_006777837.1 CDS O3K_05625 NC_018658.1 1158835 1159539 R COG1512 Beta-propeller domains of methanol dehydrogenase type; hypothetical protein complement(1158835..1159539) Escherichia coli O104:H4 str. 2011C-3493 13700788 YP_006777838.1 CDS O3K_05630 NC_018658.1 1159721 1159861 R hypothetical protein complement(1159721..1159861) Escherichia coli O104:H4 str. 2011C-3493 13700789 YP_006777839.1 CDS O3K_05635 NC_018658.1 1160000 1160671 D COG0602 Organic radical activating enzymes; hypothetical protein 1160000..1160671 Escherichia coli O104:H4 str. 2011C-3493 13700790 YP_006777840.1 CDS O3K_05640 NC_018658.1 1161313 1161534 R hypothetical protein complement(1161313..1161534) Escherichia coli O104:H4 str. 2011C-3493 13700791 YP_006777841.1 CDS O3K_05645 NC_018658.1 1162471 1163949 R COG1070 Sugar (pentulose and hexulose) kinases; kinase complement(1162471..1163949) Escherichia coli O104:H4 str. 2011C-3493 13700792 YP_006777842.1 CDS O3K_05650 NC_018658.1 1163976 1165253 R COG0477 Permeases of the major facilitator superfamily; transporter complement(1163976..1165253) Escherichia coli O104:H4 str. 2011C-3493 13700793 YP_006777843.1 CDS O3K_05655 NC_018658.1 1165572 1166357 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1165572..1166357 Escherichia coli O104:H4 str. 2011C-3493 13700794 YP_006777844.1 CDS O3K_05660 NC_018658.1 1166427 1167881 D COG0277 FAD/FMN-containing dehydrogenases; putative FAD containing dehydrogenase 1166427..1167881 Escherichia coli O104:H4 str. 2011C-3493 13700795 YP_006777845.1 CDS O3K_05665 NC_018658.1 1167975 1169312 D COG0477 Permeases of the major facilitator superfamily; transporter 1167975..1169312 Escherichia coli O104:H4 str. 2011C-3493 13700796 YP_006777846.1 CDS O3K_05670 NC_018658.1 1169290 1170069 D COG2086 Electron transfer flavoprotein, beta subunit; putative electron transfer flavoprotein 1169290..1170069 Escherichia coli O104:H4 str. 2011C-3493 13700797 YP_006777847.1 CDS O3K_05675 NC_018658.1 1170066 1170926 D COG2025 Electron transfer flavoprotein, alpha subunit; flavoprotein 1170066..1170926 Escherichia coli O104:H4 str. 2011C-3493 13700798 YP_006777848.1 CDS O3K_05680 NC_018658.1 1171074 1171649 R COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding); putative anti-terminator regulatory protein complement(1171074..1171649) Escherichia coli O104:H4 str. 2011C-3493 13700799 YP_006777849.1 CDS O3K_05685 NC_018658.1 1171666 1171926 R COG2440 Ferredoxin-like protein; 4Fe-4S binding protein complement(1171666..1171926) Escherichia coli O104:H4 str. 2011C-3493 13700800 YP_006777850.1 CDS O3K_05690 NC_018658.1 1171917 1173188 R COG0644 Dehydrogenases (flavoproteins); oxidoreductase with FAD/NAD(P)-binding domain complement(1171917..1173188) Escherichia coli O104:H4 str. 2011C-3493 13700801 YP_006777851.1 CDS O3K_05695 NC_018658.1 1173266 1173628 R COG0720 6-pyruvoyl-tetrahydropterin synthase; 6-pyruvoyl tetrahydrobiopterin synthase complement(1173266..1173628) Escherichia coli O104:H4 str. 2011C-3493 13700802 YP_006777852.1 CDS cysJ NC_018658.1 1173947 1175746 D COG0369 Sulfite reductase, alpha subunit (flavoprotein); sulfite reductase subunit alpha 1173947..1175746 Escherichia coli O104:H4 str. 2011C-3493 13700803 YP_006777853.1 CDS O3K_05705 NC_018658.1 1175746 1177458 D COG0155 Sulfite reductase, beta subunit (hemoprotein); sulfite reductase subunit beta 1175746..1177458 Escherichia coli O104:H4 str. 2011C-3493 13700804 YP_006777854.1 CDS O3K_05710 NC_018658.1 1177532 1178266 D COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; phosphoadenosine phosphosulfate reductase 1177532..1178266 Escherichia coli O104:H4 str. 2011C-3493 13700805 YP_006777855.1 CDS O3K_05715 NC_018658.1 1178531 1178683 D small toxic membrane polypeptide 1178531..1178683 Escherichia coli O104:H4 str. 2011C-3493 13700806 YP_006777856.1 CDS O3K_05720 NC_018658.1 1178760 1179872 D COG3385 FOG: Transposase and inactivated derivatives; putative transposase insL for insertion sequence IS186 1178760..1179872 Escherichia coli O104:H4 str. 2011C-3493 13700807 YP_006777857.1 CDS O3K_05725 NC_018658.1 1180268 1182925 D COG1203 Predicted helicases; hypothetical protein 1180268..1182925 Escherichia coli O104:H4 str. 2011C-3493 13700808 YP_006777858.1 CDS O3K_05730 NC_018658.1 1183023 1184585 D hypothetical protein 1183023..1184585 Escherichia coli O104:H4 str. 2011C-3493 13700809 YP_006777859.1 CDS O3K_05735 NC_018658.1 1184582 1185118 D hypothetical protein 1184582..1185118 Escherichia coli O104:H4 str. 2011C-3493 13700810 YP_006777860.1 CDS O3K_05740 NC_018658.1 1185130 1186185 D hypothetical protein 1185130..1186185 Escherichia coli O104:H4 str. 2011C-3493 13700811 YP_006777861.1 CDS O3K_05745 NC_018658.1 1186196 1186942 D hypothetical protein 1186196..1186942 Escherichia coli O104:H4 str. 2011C-3493 13700812 YP_006777862.1 CDS O3K_05750 NC_018658.1 1186924 1187574 D hypothetical protein 1186924..1187574 Escherichia coli O104:H4 str. 2011C-3493 13700813 YP_006777863.1 CDS O3K_05755 NC_018658.1 1187571 1188491 D COG1518 Uncharacterized protein predicted to be involved in DNA repair; CRISPR-associated protein Cas1 1187571..1188491 Escherichia coli O104:H4 str. 2011C-3493 13700814 YP_006777864.1 CDS O3K_05760 NC_018658.1 1188491 1188784 D putative ssRNA endonuclease 1188491..1188784 Escherichia coli O104:H4 str. 2011C-3493 13700815 YP_006777865.1 CDS O3K_05765 NC_018658.1 1189052 1190089 R COG2234 Predicted aminopeptidases; alkaline phosphatase isozyme conversion aminopeptidase complement(1189052..1190089) Escherichia coli O104:H4 str. 2011C-3493 13700816 YP_006777866.1 CDS O3K_05770 NC_018658.1 1190341 1191249 D COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; sulfate adenylyltransferase subunit 2 1190341..1191249 Escherichia coli O104:H4 str. 2011C-3493 13700817 YP_006777867.1 CDS cysN NC_018658.1 1191251 1192678 D COG2895 GTPases - Sulfate adenylate transferase subunit 1; sulfate adenylyltransferase subunit 1 1191251..1192678 Escherichia coli O104:H4 str. 2011C-3493 13700818 YP_006777868.1 CDS O3K_05780 NC_018658.1 1192678 1193283 D COG0529 Adenylylsulfate kinase and related kinases; adenylylsulfate kinase 1192678..1193283 Escherichia coli O104:H4 str. 2011C-3493 13700819 YP_006777869.1 CDS O3K_05785 NC_018658.1 1193333 1193656 D COG0665 Glycine/D-amino acid oxidases (deaminating); hypothetical protein 1193333..1193656 Escherichia coli O104:H4 str. 2011C-3493 13700820 YP_006777870.1 CDS ftsB NC_018658.1 1193850 1194161 D COG2919 Septum formation initiator; cell division protein FtsB 1193850..1194161 Escherichia coli O104:H4 str. 2011C-3493 13700821 YP_006777871.1 CDS ispD NC_018658.1 1194180 1194890 D COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1194180..1194890 Escherichia coli O104:H4 str. 2011C-3493 13700822 YP_006777872.1 CDS ispF NC_018658.1 1194890 1195369 D COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 1194890..1195369 Escherichia coli O104:H4 str. 2011C-3493 13700823 YP_006777873.1 CDS truD NC_018658.1 1195366 1196415 D COG0585 Uncharacterized conserved protein; tRNA pseudouridine synthase D 1195366..1196415 Escherichia coli O104:H4 str. 2011C-3493 13700824 YP_006777874.1 CDS surE NC_018658.1 1196396 1197157 D COG0496 Predicted acid phosphatase; 5'(3')-nucleotidase/polyphosphatase 1196396..1197157 Escherichia coli O104:H4 str. 2011C-3493 13700825 YP_006777875.1 CDS pcm NC_018658.1 1197151 1197777 D COG2518 Protein-L-isoaspartate carboxylmethyltransferase; protein-L-isoaspartate O-methyltransferase 1197151..1197777 Escherichia coli O104:H4 str. 2011C-3493 13700826 YP_006777876.1 CDS nlpD NC_018658.1 1197917 1199056 D COG0739 Membrane proteins related to metalloendopeptidases; lipoprotein NlpD 1197917..1199056 Escherichia coli O104:H4 str. 2011C-3493 13700827 YP_006777877.1 CDS O3K_05825 NC_018658.1 1199119 1200111 D COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor RpoS 1199119..1200111 Escherichia coli O104:H4 str. 2011C-3493 13700828 YP_006777878.1 CDS O3K_05830 NC_018658.1 1200232 1200639 R COG1846 Transcriptional regulators; transcriptional regulator hosA complement(1200232..1200639) Escherichia coli O104:H4 str. 2011C-3493 13700829 YP_006777879.1 CDS O3K_05835 NC_018658.1 1200786 1201379 D COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; putative phenylacrylic acid decarboxylase 1200786..1201379 Escherichia coli O104:H4 str. 2011C-3493 13700830 YP_006777880.1 CDS O3K_05840 NC_018658.1 1201379 1202806 D COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; 4-hydroxybenzoate decarboxylase 1201379..1202806 Escherichia coli O104:H4 str. 2011C-3493 13700831 YP_006777881.1 CDS O3K_05845 NC_018658.1 1202817 1203053 D non-oxidative reversible hydroxyarylic acid decarboxylase 1202817..1203053 Escherichia coli O104:H4 str. 2011C-3493 13700832 YP_006777882.1 CDS O3K_05850 NC_018658.1 1203093 1204457 R COG2610 H+/gluconate symporter and related permeases; transporter complement(1203093..1204457) Escherichia coli O104:H4 str. 2011C-3493 13700833 YP_006777883.1 CDS O3K_05855 NC_018658.1 1204546 1205322 R COG3622 Hydroxypyruvate isomerase; hypothetical protein complement(1204546..1205322) Escherichia coli O104:H4 str. 2011C-3493 13700834 YP_006777884.1 CDS O3K_05860 NC_018658.1 1205327 1205965 R COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; putative aldolase complement(1205327..1205965) Escherichia coli O104:H4 str. 2011C-3493 13700835 YP_006777885.1 CDS O3K_05865 NC_018658.1 1205962 1207224 R COG3395 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1205962..1207224) Escherichia coli O104:H4 str. 2011C-3493 13700836 YP_006777886.1 CDS O3K_05870 NC_018658.1 1207221 1208129 R COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; putative dehydrogenase complement(1207221..1208129) Escherichia coli O104:H4 str. 2011C-3493 13700837 YP_006777887.1 CDS O3K_05875 NC_018658.1 1208325 1209092 D COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 1208325..1209092 Escherichia coli O104:H4 str. 2011C-3493 13700838 YP_006777888.1 CDS O3K_05880 NC_018658.1 1209143 1209799 R COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; serine/threonine-specific protein phosphatase 2 complement(1209143..1209799) Escherichia coli O104:H4 str. 2011C-3493 13700839 YP_006777889.1 CDS O3K_05885 NC_018658.1 1209905 1212466 R COG0249 Mismatch repair ATPase (MutS family); DNA mismatch repair protein MutS complement(1209905..1212466) Escherichia coli O104:H4 str. 2011C-3493 13700840 YP_006777890.1 CDS O3K_05890 NC_018658.1 1212542 1212721 D hypothetical protein 1212542..1212721 Escherichia coli O104:H4 str. 2011C-3493 13700841 YP_006777891.1 CDS O3K_05895 NC_018658.1 1212753 1213106 D hypothetical protein 1212753..1213106 Escherichia coli O104:H4 str. 2011C-3493 13700842 YP_006777892.1 CDS O3K_05900 NC_018658.1 1213143 1215221 R COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; formate hydrogenlyase transcriptional activator FhlA complement(1213143..1215221) Escherichia coli O104:H4 str. 2011C-3493 13700843 YP_006777893.1 CDS O3K_05905 NC_018658.1 1215295 1216305 R COG0309 Hydrogenase maturation factor; hydrogenase expression/formation protein HypE complement(1215295..1216305) Escherichia coli O104:H4 str. 2011C-3493 13700844 YP_006777894.1 CDS O3K_05910 NC_018658.1 1216302 1217423 R COG0409 Hydrogenase maturation factor; hydrogenase expression/formation protein HypD complement(1216302..1217423) Escherichia coli O104:H4 str. 2011C-3493 13700845 YP_006777895.1 CDS O3K_05915 NC_018658.1 1217423 1217695 R COG0298 Hydrogenase maturation factor; hydrogenase assembly chaperone complement(1217423..1217695) Escherichia coli O104:H4 str. 2011C-3493 13700846 YP_006777896.1 CDS O3K_05920 NC_018658.1 1217686 1218558 R COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; hydrogenase nickel incorporation protein HypB complement(1217686..1218558) Escherichia coli O104:H4 str. 2011C-3493 13700847 YP_006777897.1 CDS hypA NC_018658.1 1218562 1218912 R COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); hydrogenase nickel incorporation protein complement(1218562..1218912) Escherichia coli O104:H4 str. 2011C-3493 13700848 YP_006777898.1 CDS O3K_05930 NC_018658.1 1219123 1219584 D formate hydrogenlyase regulatory protein HycA 1219123..1219584 Escherichia coli O104:H4 str. 2011C-3493 13700849 YP_006777899.1 CDS O3K_05935 NC_018658.1 1219500 1219808 R hypothetical protein complement(1219500..1219808) Escherichia coli O104:H4 str. 2011C-3493 13700850 YP_006777900.1 CDS O3K_05940 NC_018658.1 1219709 1220320 D COG1142 Fe-S-cluster-containing hydrogenase components 2; formate hydrogenlyase subunit B 1219709..1220320 Escherichia coli O104:H4 str. 2011C-3493 13700851 YP_006777901.1 CDS O3K_05945 NC_018658.1 1220317 1222143 D COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; formate hydrogenlyase subunit 3 1220317..1222143 Escherichia coli O104:H4 str. 2011C-3493 13700852 YP_006777902.1 CDS O3K_05950 NC_018658.1 1222146 1223069 D COG0650 Formate hydrogenlyase subunit 4; hydrogenase 3, membrane subunit HycD 1222146..1223069 Escherichia coli O104:H4 str. 2011C-3493 13700853 YP_006777903.1 CDS O3K_05955 NC_018658.1 1223087 1224796 D COG3262 Ni,Fe-hydrogenase III component G; formate hydrogenlyase subunit E 1223087..1224796 Escherichia coli O104:H4 str. 2011C-3493 13700854 YP_006777904.1 CDS O3K_05960 NC_018658.1 1224806 1225348 D COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); formate hydrogenlyase complex iron-sulfur subunit 1224806..1225348 Escherichia coli O104:H4 str. 2011C-3493 13700855 YP_006777905.1 CDS O3K_05965 NC_018658.1 1225348 1226115 D COG3260 Ni,Fe-hydrogenase III small subunit; hydrogenase 3 and formate hydrogenase complex, HycG subunit 1225348..1226115 Escherichia coli O104:H4 str. 2011C-3493 13700856 YP_006777906.1 CDS O3K_05970 NC_018658.1 1226112 1226522 D formate hydrogenlyase maturation protein HycH 1226112..1226522 Escherichia coli O104:H4 str. 2011C-3493 13700857 YP_006777907.1 CDS hycI NC_018658.1 1226515 1226985 D COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 3 maturation protease 1226515..1226985 Escherichia coli O104:H4 str. 2011C-3493 13700858 YP_006777908.1 CDS O3K_05980 NC_018658.1 1227010 1227783 D hypothetical protein 1227010..1227783 Escherichia coli O104:H4 str. 2011C-3493 13700859 YP_006777909.1 CDS O3K_05985 NC_018658.1 1227854 1228273 D COG5499 Predicted transcription regulator containing HTH domain; HTH-type transcriptional regulator ygjM 1227854..1228273 Escherichia coli O104:H4 str. 2011C-3493 13700860 YP_006777910.1 CDS O3K_05990 NC_018658.1 1228518 1229498 D COG3547 Transposase and inactivated derivatives; IS621 transposase 1228518..1229498 Escherichia coli O104:H4 str. 2011C-3493 13700861 YP_006777911.1 CDS O3K_05995 NC_018658.1 1229666 1231090 R COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; cryptic 6-phospho-beta-glucosidase complement(1229666..1231090) Escherichia coli O104:H4 str. 2011C-3493 13700862 YP_006777912.1 CDS O3K_06000 NC_018658.1 1231099 1232556 R COG1264 Phosphotransferase system IIB components; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC complement(1231099..1232556) Escherichia coli O104:H4 str. 2011C-3493 13700863 YP_006777913.1 CDS O3K_06005 NC_018658.1 1232813 1233826 D COG1609 Transcriptional regulators; transcriptional regulator 1232813..1233826 Escherichia coli O104:H4 str. 2011C-3493 13700864 YP_006777914.1 CDS O3K_06010 NC_018658.1 1233975 1234502 D COG1142 Fe-S-cluster-containing hydrogenase components 2; formate dehydrogenase-H ferredoxin subunit 1233975..1234502 Escherichia coli O104:H4 str. 2011C-3493 13700865 YP_006777915.1 CDS O3K_06015 NC_018658.1 1234655 1236907 D COG0068 Hydrogenase maturation factor; hydrogenase maturation protein 1234655..1236907 Escherichia coli O104:H4 str. 2011C-3493 13700866 YP_006777916.1 CDS O3K_06020 NC_018658.1 1237133 1238266 R COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; NADH:flavorubredoxin oxidoreductase complement(1237133..1238266) Escherichia coli O104:H4 str. 2011C-3493 13700867 YP_006777917.1 CDS O3K_06025 NC_018658.1 1238263 1239702 R COG0426 Uncharacterized flavoproteins; anaerobic nitric oxide reductase flavorubredoxin complement(1238263..1239702) Escherichia coli O104:H4 str. 2011C-3493 13702656 YP_006777918.1 CDS O3K_06030 NC_018658.1 1239889 1241403 D COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; anaerobic nitric oxide reductase transcriptional regulator 1239889..1241403 Escherichia coli O104:H4 str. 2011C-3493 13702657 YP_006777919.1 CDS gutQ NC_018658.1 1241400 1242365 R COG0794 Predicted sugar phosphate isomerase involved in capsule formation; D-arabinose 5-phosphate isomerase complement(1241400..1242365) Escherichia coli O104:H4 str. 2011C-3493 13702658 YP_006777920.1 CDS srlR NC_018658.1 1242358 1243131 R COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor SrlR complement(1242358..1243131) Escherichia coli O104:H4 str. 2011C-3493 13702659 YP_006777921.1 CDS O3K_06045 NC_018658.1 1243198 1243557 R COG4578 Glucitol operon activator; DNA-binding transcriptional activator GutM complement(1243198..1243557) Escherichia coli O104:H4 str. 2011C-3493 13702660 YP_006777922.1 CDS O3K_06050 NC_018658.1 1243662 1244441 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); sorbitol-6-phosphate dehydrogenase complement(1243662..1244441) Escherichia coli O104:H4 str. 2011C-3493 13702661 YP_006777923.1 CDS O3K_06055 NC_018658.1 1244445 1244816 R COG3731 Phosphotransferase system sorbitol-specific component IIA; PTS system glucitol/sorbitol-specific transporter subunit IIA complement(1244445..1244816) Escherichia coli O104:H4 str. 2011C-3493 13702662 YP_006777924.1 CDS O3K_06060 NC_018658.1 1244827 1245786 R COG3732 Phosphotransferase system sorbitol-specific component IIBC; PTS system glucitol/sorbitol-specific transporter subunit IIB complement(1244827..1245786) Escherichia coli O104:H4 str. 2011C-3493 13702663 YP_006777925.1 CDS O3K_06065 NC_018658.1 1245783 1246346 R COG3730 Phosphotransferase system sorbitol-specific component IIC; glucitol/sorbitol permease IIC component complement(1245783..1246346) Escherichia coli O104:H4 str. 2011C-3493 13702664 YP_006777926.1 CDS O3K_06070 NC_018658.1 1246602 1247687 D COG2951 Membrane-bound lytic murein transglycosylase B; murein hydrolase B 1246602..1247687 Escherichia coli O104:H4 str. 2011C-3493 13702665 YP_006777927.1 CDS O3K_06075 NC_018658.1 1247832 1248329 D COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein 1247832..1248329 Escherichia coli O104:H4 str. 2011C-3493 13702666 YP_006777928.1 CDS recA NC_018658.1 1248409 1249470 D COG0468 RecA/RadA recombinase; recombinase A 1248409..1249470 Escherichia coli O104:H4 str. 2011C-3493 13702667 YP_006777929.1 CDS recX NC_018658.1 1249713 1250213 D COG2137 Uncharacterized protein conserved in bacteria; recombination regulator RecX 1249713..1250213 Escherichia coli O104:H4 str. 2011C-3493 13702668 YP_006777930.1 CDS O3K_06090 NC_018658.1 1250254 1250403 R hypothetical protein complement(1250254..1250403) Escherichia coli O104:H4 str. 2011C-3493 13702669 YP_006777931.1 CDS alaS NC_018658.1 1250341 1252971 D COG0013 Alanyl-tRNA synthetase; alanyl-tRNA synthetase 1250341..1252971 Escherichia coli O104:H4 str. 2011C-3493 13702670 YP_006777932.1 CDS O3K_06100 NC_018658.1 1253206 1253391 D COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); carbon storage regulator 1253206..1253391 Escherichia coli O104:H4 str. 2011C-3493 13702671 YP_006777933.1 CDS O3K_06105 NC_018658.1 1254433 1254999 D COG0637 Predicted phosphatase/phosphohexomutase; fructose-1-P/6-phosphogluconate phosphatase 1254433..1254999 Escherichia coli O104:H4 str. 2011C-3493 13702675 YP_006777934.1 CDS O3K_06110 NC_018658.1 1254996 1255424 D COG1238 Predicted membrane protein; hypothetical protein 1254996..1255424 Escherichia coli O104:H4 str. 2011C-3493 13702676 YP_006777935.1 CDS O3K_06115 NC_018658.1 1255497 1257053 D COG2918 Gamma-glutamylcysteine synthetase; glutamate--cysteine ligase 1255497..1257053 Escherichia coli O104:H4 str. 2011C-3493 13702677 YP_006777936.1 CDS O3K_06120 NC_018658.1 1257203 1257718 D COG1854 LuxS protein involved in autoinducer AI2 synthesis; S-ribosylhomocysteinase 1257203..1257718 Escherichia coli O104:H4 str. 2011C-3493 13702678 YP_006777937.1 CDS O3K_06125 NC_018658.1 1257782 1259320 R COG0477 Permeases of the major facilitator superfamily; membrane translocase complement(1257782..1259320) Escherichia coli O104:H4 str. 2011C-3493 13702679 YP_006777938.1 CDS O3K_06130 NC_018658.1 1259337 1260509 R COG1566 Multidrug resistance efflux pump; multidrug efflux system protein EmrA complement(1259337..1260509) Escherichia coli O104:H4 str. 2011C-3493 13702680 YP_006777939.1 CDS O3K_06135 NC_018658.1 1260636 1261166 R COG1846 Transcriptional regulators; transcriptional repressor MprA complement(1260636..1261166) Escherichia coli O104:H4 str. 2011C-3493 13702681 YP_006777940.1 CDS O3K_06140 NC_018658.1 1261257 1261592 R putative L-valine exporter complement(1261257..1261592) Escherichia coli O104:H4 str. 2011C-3493 13702682 YP_006777941.1 CDS O3K_06145 NC_018658.1 1261582 1262319 R COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); branched chain amino acid exporter (LIV-E) family protein complement(1261582..1262319) Escherichia coli O104:H4 str. 2011C-3493 13702683 YP_006777942.1 CDS O3K_06150 NC_018658.1 1262443 1263627 R COG0477 Permeases of the major facilitator superfamily; transport protein (ousB-like) complement(1262443..1263627) Escherichia coli O104:H4 str. 2011C-3493 13702684 YP_006777943.1 CDS proX NC_018658.1 1263819 1264811 R COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components; glycine betaine transporter periplasmic subunit complement(1263819..1264811) Escherichia coli O104:H4 str. 2011C-3493 13702685 YP_006777944.1 CDS O3K_06160 NC_018658.1 1264868 1265932 R COG4176 ABC-type proline/glycine betaine transport system, permease component; glycine betaine transporter membrane protein complement(1264868..1265932) Escherichia coli O104:H4 str. 2011C-3493 13702686 YP_006777945.1 CDS O3K_06165 NC_018658.1 1265925 1267127 R COG4175 ABC-type proline/glycine betaine transport system, ATPase component; glycine betaine transporter ATP-binding subunit complement(1265925..1267127) Escherichia coli O104:H4 str. 2011C-3493 13702687 YP_006777946.1 CDS nrdF NC_018658.1 1267482 1268441 R COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta complement(1267482..1268441) Escherichia coli O104:H4 str. 2011C-3493 13702688 YP_006777947.1 CDS O3K_06175 NC_018658.1 1268451 1270595 R COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha complement(1268451..1270595) Escherichia coli O104:H4 str. 2011C-3493 13702689 YP_006777948.1 CDS nrdI NC_018658.1 1270568 1270978 R COG1780 Protein involved in ribonucleotide reduction; ribonucleotide reductase stimulatory protein complement(1270568..1270978) Escherichia coli O104:H4 str. 2011C-3493 13702690 YP_006777949.1 CDS O3K_06185 NC_018658.1 1270975 1271220 R COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein complement(1270975..1271220) Escherichia coli O104:H4 str. 2011C-3493 13702691 YP_006777950.1 CDS O3K_06190 NC_018658.1 1271468 1271797 R COG4575 Uncharacterized conserved protein; hypothetical protein complement(1271468..1271797) Escherichia coli O104:H4 str. 2011C-3493 13702692 YP_006777951.1 CDS O3K_06195 NC_018658.1 1271949 1272293 D hypothetical protein 1271949..1272293 Escherichia coli O104:H4 str. 2011C-3493 13702693 YP_006777952.1 CDS O3K_06200 NC_018658.1 1272330 1272779 R hypothetical protein complement(1272330..1272779) Escherichia coli O104:H4 str. 2011C-3493 13702694 YP_006777953.1 CDS O3K_06205 NC_018658.1 1273447 1273851 D COG2916 DNA-binding protein H-NS; DNA binding protein 1273447..1273851 Escherichia coli O104:H4 str. 2011C-3493 13702695 YP_006777954.1 CDS O3K_06210 NC_018658.1 1273898 1274422 R COG0607 Rhodanese-related sulfurtransferase; inner membrane protein complement(1273898..1274422) Escherichia coli O104:H4 str. 2011C-3493 13702696 YP_006777955.1 CDS O3K_06215 NC_018658.1 1274432 1274731 R COG0640 Predicted transcriptional regulators; putative DNA-binding transcriptional regulator complement(1274432..1274731) Escherichia coli O104:H4 str. 2011C-3493 13702697 YP_006777956.1 CDS O3K_06220 NC_018658.1 1274914 1275072 D COG0401 Uncharacterized homolog of Blt101; hypothetical protein 1274914..1275072 Escherichia coli O104:H4 str. 2011C-3493 13702698 YP_006777957.1 CDS O3K_06225 NC_018658.1 1275156 1275605 D COG1652 Uncharacterized protein containing LysM domain; LysM domain/BON superfamily protein 1275156..1275605 Escherichia coli O104:H4 str. 2011C-3493 13702699 YP_006777958.1 CDS O3K_06230 NC_018658.1 1275606 1276268 R COG1802 Transcriptional regulators; DNA-binding transcriptional regulator CsiR complement(1275606..1276268) Escherichia coli O104:H4 str. 2011C-3493 13702700 YP_006777959.1 CDS O3K_06235 NC_018658.1 1276289 1277689 R COG1113 Gamma-aminobutyrate permease and related permeases; gamma-aminobutyrate transporter complement(1276289..1277689) Escherichia coli O104:H4 str. 2011C-3493 13702701 YP_006777960.1 CDS O3K_06240 NC_018658.1 1278000 1279280 R COG0160 4-aminobutyrate aminotransferase and related aminotransferases; 4-aminobutyrate aminotransferase complement(1278000..1279280) Escherichia coli O104:H4 str. 2011C-3493 13702702 YP_006777961.1 CDS gabD NC_018658.1 1279294 1280742 R COG1012 NAD-dependent aldehyde dehydrogenases; succinate-semialdehyde dehydrogenase I complement(1279294..1280742) Escherichia coli O104:H4 str. 2011C-3493 13702703 YP_006777962.1 CDS O3K_06250 NC_018658.1 1280765 1282033 R COG0579 Predicted dehydrogenase; hydroxyglutarate oxidase complement(1280765..1282033) Escherichia coli O104:H4 str. 2011C-3493 13702704 YP_006777963.1 CDS O3K_06255 NC_018658.1 1282053 1283030 R carbon starvation induced protein complement(1282053..1283030) Escherichia coli O104:H4 str. 2011C-3493 13702705 YP_006777964.1 CDS O3K_06260 NC_018658.1 1283366 1283638 R hypothetical protein complement(1283366..1283638) Escherichia coli O104:H4 str. 2011C-3493 13702706 YP_006777965.1 CDS O3K_06265 NC_018658.1 1283973 1285268 R COG0366 Glycosidases; putative alpha-amylase complement(1283973..1285268) Escherichia coli O104:H4 str. 2011C-3493 13702707 YP_006777966.1 CDS O3K_06285 NC_018658.1 1289729 1290475 R COG2801 Transposase and inactivated derivatives; putative IS602 transposase OrfB complement(1289729..1290475) Escherichia coli O104:H4 str. 2011C-3493 13702709 YP_006777967.1 CDS O3K_06290 NC_018658.1 1290595 1290942 R COG2963 Transposase and inactivated derivatives; putative IS602 transposase OrfA complement(1290595..1290942) Escherichia coli O104:H4 str. 2011C-3493 13702710 YP_006777968.1 CDS O3K_06300 NC_018658.1 1291428 1291667 R COG3311 Predicted transcriptional regulator; phage transcriptional regulator AlpA complement(1291428..1291667) Escherichia coli O104:H4 str. 2011C-3493 13702711 YP_006777969.1 CDS O3K_06305 NC_018658.1 1291781 1292662 D hypothetical protein 1291781..1292662 Escherichia coli O104:H4 str. 2011C-3493 13702712 YP_006777970.1 CDS O3K_06310 NC_018658.1 1292930 1293109 R hypothetical protein complement(1292930..1293109) Escherichia coli O104:H4 str. 2011C-3493 13702713 YP_006777971.1 CDS O3K_06315 NC_018658.1 1293096 1293842 R hypothetical protein complement(1293096..1293842) Escherichia coli O104:H4 str. 2011C-3493 13702714 YP_006777972.1 CDS O3K_06320 NC_018658.1 1293888 1297739 R COG2925 Exonuclease I; hypothetical protein complement(1293888..1297739) Escherichia coli O104:H4 str. 2011C-3493 13702715 YP_006777973.1 CDS O3K_06325 NC_018658.1 1298207 1301953 D hypothetical protein 1298207..1301953 Escherichia coli O104:H4 str. 2011C-3493 13702716 YP_006777974.1 CDS O3K_06330 NC_018658.1 1302092 1303333 R COG0582 Integrase; integrase complement(1302092..1303333) Escherichia coli O104:H4 str. 2011C-3493 13702717 YP_006777975.1 CDS smpB NC_018658.1 1304116 1304598 R COG0691 tmRNA-binding protein; SsrA-binding protein complement(1304116..1304598) Escherichia coli O104:H4 str. 2011C-3493 13702718 YP_006777976.1 CDS O3K_06340 NC_018658.1 1304769 1305206 D COG2867 Oligoketide cyclase/lipid transport protein; hypothetical protein 1304769..1305206 Escherichia coli O104:H4 str. 2011C-3493 13702719 YP_006777977.1 CDS O3K_06345 NC_018658.1 1305196 1305486 D COG2914 Uncharacterized protein conserved in bacteria; hypothetical protein 1305196..1305486 Escherichia coli O104:H4 str. 2011C-3493 13702720 YP_006777978.1 CDS O3K_06350 NC_018658.1 1305548 1305889 R COG2913 Small protein A (tmRNA-binding); outer membrane biogenesis protein BamE complement(1305548..1305889) Escherichia coli O104:H4 str. 2011C-3493 13702721 YP_006777979.1 CDS O3K_06355 NC_018658.1 1306038 1307699 R COG0497 ATPase involved in DNA repair; recombination and repair protein complement(1306038..1307699) Escherichia coli O104:H4 str. 2011C-3493 13702722 YP_006777980.1 CDS O3K_06360 NC_018658.1 1307785 1308663 R COG0061 Predicted sugar kinase; inorganic polyphosphate/ATP-NAD kinase complement(1307785..1308663) Escherichia coli O104:H4 str. 2011C-3493 13702723 YP_006777981.1 CDS O3K_06365 NC_018658.1 1308786 1309379 D COG0576 Molecular chaperone GrpE (heat shock protein); heat shock protein HSP70 cofactor 1308786..1309379 Escherichia coli O104:H4 str. 2011C-3493 13702724 YP_006777982.1 CDS O3K_06370 NC_018658.1 1309434 1310630 R COG4536 Putative Mg2+ and Co2+ transporter CorB; hypothetical protein complement(1309434..1310630) Escherichia coli O104:H4 str. 2011C-3493 13702725 YP_006777983.1 CDS O3K_06375 NC_018658.1 1310741 1311532 R COG4137 ABC-type uncharacterized transport system, permease component; hypothetical protein complement(1310741..1311532) Escherichia coli O104:H4 str. 2011C-3493 13702726 YP_006777984.1 CDS O3K_06380 NC_018658.1 1311699 1313060 D COG0541 Signal recognition particle GTPase; signal recognition particle protein 1311699..1313060 Escherichia coli O104:H4 str. 2011C-3493 13702727 YP_006777985.1 CDS rpsP NC_018658.1 1313197 1313445 D COG0228 Ribosomal protein S16; 30S ribosomal protein S16 1313197..1313445 Escherichia coli O104:H4 str. 2011C-3493 13702728 YP_006777986.1 CDS rimM NC_018658.1 1313464 1314012 D COG0806 RimM protein, required for 16S rRNA processing; 16S rRNA-processing protein RimM 1313464..1314012 Escherichia coli O104:H4 str. 2011C-3493 13702729 YP_006777987.1 CDS trmD NC_018658.1 1314043 1314810 D COG0336 tRNA-(guanine-N1)-methyltransferase; tRNA (guanine-N(1)-)-methyltransferase 1314043..1314810 Escherichia coli O104:H4 str. 2011C-3493 13702730 YP_006777988.1 CDS rplS NC_018658.1 1314852 1315199 D COG0335 Ribosomal protein L19; 50S ribosomal protein L19 1314852..1315199 Escherichia coli O104:H4 str. 2011C-3493 13702731 YP_006777989.1 CDS O3K_06405 NC_018658.1 1315276 1315758 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; putative outer membrane lipoprotein complement(1315276..1315758) Escherichia coli O104:H4 str. 2011C-3493 13702732 YP_006777990.1 CDS O3K_06410 NC_018658.1 1315774 1317000 R COG2199 FOG: GGDEF domain; putative inner membrane diguanylate cyclase complement(1315774..1317000) Escherichia coli O104:H4 str. 2011C-3493 13702733 YP_006777991.1 CDS O3K_06415 NC_018658.1 1316990 1317508 R hypothetical protein complement(1316990..1317508) Escherichia coli O104:H4 str. 2011C-3493 13702734 YP_006777992.1 CDS O3K_06420 NC_018658.1 1317658 1318023 R COG0178 Excinuclease ATPase subunit; lipoprotein complement(1317658..1318023) Escherichia coli O104:H4 str. 2011C-3493 13702735 YP_006777993.1 CDS O3K_06425 NC_018658.1 1318233 1319303 D COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase 1318233..1319303 Escherichia coli O104:H4 str. 2011C-3493 13702736 YP_006777994.1 CDS tyrA NC_018658.1 1319314 1320435 D COG1605 Chorismate mutase; bifunctional chorismate mutase/prephenate dehydrogenase 1319314..1320435 Escherichia coli O104:H4 str. 2011C-3493 13702737 YP_006777995.1 CDS pheA NC_018658.1 1320478 1321638 R COG1605 Chorismate mutase; bifunctional chorismate mutase/prephenate dehydratase complement(1320478..1321638) Escherichia coli O104:H4 str. 2011C-3493 13702738 YP_006777996.1 CDS O3K_06440 NC_018658.1 1321888 1322229 R COG1544 Ribosome-associated protein Y (PSrp-1); translation inhibitor protein RaiA complement(1321888..1322229) Escherichia coli O104:H4 str. 2011C-3493 13702739 YP_006777997.1 CDS O3K_06445 NC_018658.1 1322500 1323237 R COG4105 DNA uptake lipoprotein; outer membrane biogenesis protein BamD complement(1322500..1323237) Escherichia coli O104:H4 str. 2011C-3493 13702740 YP_006777998.1 CDS rluD NC_018658.1 1323372 1324352 D COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA pseudouridine synthase D 1323372..1324352 Escherichia coli O104:H4 str. 2011C-3493 13702741 YP_006777999.1 CDS O3K_06455 NC_018658.1 1324349 1325080 D COG1496 Uncharacterized conserved protein; hypothetical protein 1324349..1325080 Escherichia coli O104:H4 str. 2011C-3493 13702742 YP_006778000.1 CDS O3K_06460 NC_018658.1 1325210 1327783 D COG0542 ATPases with chaperone activity, ATP-binding subunit; protein disaggregation chaperone 1325210..1327783 Escherichia coli O104:H4 str. 2011C-3493 13702743 YP_006778001.1 CDS O3K_06465 NC_018658.1 1333649 1334947 D COG0477 Permeases of the major facilitator superfamily; alpha-ketoglutarate transporter 1333649..1334947 Escherichia coli O104:H4 str. 2011C-3493 13702748 YP_006778002.1 CDS O3K_06470 NC_018658.1 1334944 1335267 R COG5544 Predicted periplasmic lipoprotein; lipoprotein complement(1334944..1335267) Escherichia coli O104:H4 str. 2011C-3493 13702749 YP_006778003.1 CDS pssA NC_018658.1 1335313 1336668 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phosphatidylserine synthase complement(1335313..1336668) Escherichia coli O104:H4 str. 2011C-3493 13702750 YP_006778004.1 CDS O3K_06480 NC_018658.1 1336782 1339442 R COG1042 Acyl-CoA synthetase (NDP forming); acyl-CoA synthetase NAD(P)-binding subunit/ATP-binding subunit complement(1336782..1339442) Escherichia coli O104:H4 str. 2011C-3493 13702751 YP_006778005.1 CDS O3K_06485 NC_018658.1 1339474 1340172 R COG3148 Uncharacterized conserved protein; DTW domain-containing protein yfiP complement(1339474..1340172) Escherichia coli O104:H4 str. 2011C-3493 13702752 YP_006778006.1 CDS O3K_06490 NC_018658.1 1340241 1340660 R COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 2 complement(1340241..1340660) Escherichia coli O104:H4 str. 2011C-3493 13702753 YP_006778007.1 CDS O3K_06495 NC_018658.1 1340867 1341904 D COG0566 rRNA methylases; methyltransferase 1340867..1341904 Escherichia coli O104:H4 str. 2011C-3493 13702754 YP_006778008.1 CDS O3K_06500 NC_018658.1 1341952 1342641 R COG0692 Uracil DNA glycosylase; uracil-DNA glycosylase complement(1341952..1342641) Escherichia coli O104:H4 str. 2011C-3493 13702755 YP_006778009.1 CDS O3K_06505 NC_018658.1 1342946 1343329 D COG3445 Acid-induced glycyl radical enzyme; autonomous glycyl radical cofactor GrcA 1342946..1343329 Escherichia coli O104:H4 str. 2011C-3493 13702756 YP_006778010.1 CDS O3K_06510 NC_018658.1 1343384 1343971 R COG1280 Putative threonine efflux protein; cysteine/O-acetylserine exporter complement(1343384..1343971) Escherichia coli O104:H4 str. 2011C-3493 13702757 YP_006778011.1 CDS O3K_06515 NC_018658.1 1344074 1344955 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 1344074..1344955 Escherichia coli O104:H4 str. 2011C-3493 13702758 YP_006778012.1 CDS O3K_06520 NC_018658.1 1345006 1345158 R hypothetical protein complement(1345006..1345158) Escherichia coli O104:H4 str. 2011C-3493 13702759 YP_006778013.1 CDS O3K_06525 NC_018658.1 1345164 1346498 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase SrmB complement(1345164..1346498) Escherichia coli O104:H4 str. 2011C-3493 13702760 YP_006778014.1 CDS O3K_06530 NC_018658.1 1346630 1347367 D COG4123 Predicted O-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase 1346630..1347367 Escherichia coli O104:H4 str. 2011C-3493 13702761 YP_006778015.1 CDS O3K_06535 NC_018658.1 1347352 1348974 R COG0029 Aspartate oxidase; L-aspartate oxidase complement(1347352..1348974) Escherichia coli O104:H4 str. 2011C-3493 13702762 YP_006778016.1 CDS O3K_06540 NC_018658.1 1349230 1349385 D hypothetical protein 1349230..1349385 Escherichia coli O104:H4 str. 2011C-3493 13702763 YP_006778017.1 CDS O3K_06545 NC_018658.1 1349382 1349957 D COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor RpoE 1349382..1349957 Escherichia coli O104:H4 str. 2011C-3493 13702764 YP_006778018.1 CDS O3K_06550 NC_018658.1 1349990 1350640 D COG3073 Negative regulator of sigma E activity; anti-RNA polymerase sigma factor SigE 1349990..1350640 Escherichia coli O104:H4 str. 2011C-3493 13702765 YP_006778019.1 CDS rseB NC_018658.1 1350640 1351596 D COG3026 Negative regulator of sigma E activity; anti-sigma E factor 1350640..1351596 Escherichia coli O104:H4 str. 2011C-3493 13702766 YP_006778020.1 CDS O3K_06560 NC_018658.1 1351593 1352072 D COG3086 Positive regulator of sigma E activity; SoxR reducing system protein RseC 1351593..1352072 Escherichia coli O104:H4 str. 2011C-3493 13702767 YP_006778021.1 CDS O3K_06565 NC_018658.1 1352270 1354069 D COG0481 Membrane GTPase LepA; GTP-binding protein LepA 1352270..1354069 Escherichia coli O104:H4 str. 2011C-3493 13702768 YP_006778022.1 CDS O3K_06570 NC_018658.1 1354085 1355059 D COG0681 Signal peptidase I; signal peptidase I 1354085..1355059 Escherichia coli O104:H4 str. 2011C-3493 13702769 YP_006778023.1 CDS rnc NC_018658.1 1355332 1356012 D COG0571 dsRNA-specific ribonuclease; ribonuclease III 1355332..1356012 Escherichia coli O104:H4 str. 2011C-3493 13702770 YP_006778024.1 CDS era NC_018658.1 1356009 1356914 D COG1159 GTPase; GTPase Era 1356009..1356914 Escherichia coli O104:H4 str. 2011C-3493 13702771 YP_006778025.1 CDS recO NC_018658.1 1356926 1357654 D COG1381 Recombinational DNA repair protein (RecF pathway); DNA repair protein RecO 1356926..1357654 Escherichia coli O104:H4 str. 2011C-3493 13702772 YP_006778026.1 CDS O3K_06590 NC_018658.1 1357666 1358397 D COG0854 Pyridoxal phosphate biosynthesis protein; pyridoxine 5'-phosphate synthase 1357666..1358397 Escherichia coli O104:H4 str. 2011C-3493 13702773 YP_006778027.1 CDS acpS NC_018658.1 1358397 1358777 D COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); 4'-phosphopantetheinyl transferase 1358397..1358777 Escherichia coli O104:H4 str. 2011C-3493 13702774 YP_006778028.1 CDS O3K_06600 NC_018658.1 1359197 1359277 D toxic membrane protein 1359197..1359277 Escherichia coli O104:H4 str. 2011C-3493 13702775 YP_006778029.1 CDS O3K_06605 NC_018658.1 1359471 1359731 R COG1145 Ferredoxin; putative 4Fe-4S cluster-containing protein complement(1359471..1359731) Escherichia coli O104:H4 str. 2011C-3493 13702776 YP_006778030.1 CDS O3K_06610 NC_018658.1 1359787 1360635 R COG1737 Transcriptional regulators; putative DNA-binding transcriptional regulator complement(1359787..1360635) Escherichia coli O104:H4 str. 2011C-3493 13702777 YP_006778031.1 CDS O3K_06615 NC_018658.1 1360844 1361479 D COG0560 Phosphoserine phosphatase; hypothetical protein 1360844..1361479 Escherichia coli O104:H4 str. 2011C-3493 13702778 YP_006778032.1 CDS O3K_06620 NC_018658.1 1361504 1362040 D COG0590 Cytosine/adenosine deaminases; tRNA-specific adenosine deaminase 1361504..1362040 Escherichia coli O104:H4 str. 2011C-3493 13702779 YP_006778033.1 CDS O3K_06625 NC_018658.1 1362037 1363593 R COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein; membrane-bound lytic transglycosylase F complement(1362037..1363593) Escherichia coli O104:H4 str. 2011C-3493 13702780 YP_006778034.1 CDS O3K_06630 NC_018658.1 1363854 1367738 D COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine synthase 1363854..1367738 Escherichia coli O104:H4 str. 2011C-3493 13702781 YP_006778035.1 CDS O3K_06635 NC_018658.1 1368314 1369741 D COG0642 Signal transduction histidine kinase; 2-component sensor protein 1368314..1369741 Escherichia coli O104:H4 str. 2011C-3493 13702782 YP_006778036.1 CDS O3K_06640 NC_018658.1 1369906 1370619 D hypothetical protein 1369906..1370619 Escherichia coli O104:H4 str. 2011C-3493 13702783 YP_006778037.1 CDS O3K_06645 NC_018658.1 1370609 1371943 D COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; response regulator GlrR 1370609..1371943 Escherichia coli O104:H4 str. 2011C-3493 13702784 YP_006778038.1 CDS O3K_06650 NC_018658.1 1372004 1372342 D COG0347 Nitrogen regulatory protein PII; nitrogen regulatory protein P-II 1 1372004..1372342 Escherichia coli O104:H4 str. 2011C-3493 13702785 YP_006778039.1 CDS O3K_06655 NC_018658.1 1372387 1373577 R COG1017 Hemoglobin-like flavoprotein; bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2 complement(1372387..1373577) Escherichia coli O104:H4 str. 2011C-3493 13702786 YP_006778040.1 CDS glyA NC_018658.1 1373905 1375158 D COG0112 Glycine/serine hydroxymethyltransferase; serine hydroxymethyltransferase 1373905..1375158 Escherichia coli O104:H4 str. 2011C-3493 13702787 YP_006778041.1 CDS O3K_06665 NC_018658.1 1375222 1376415 R COG1940 Transcriptional regulator/sugar kinase; DNA-binding transcriptional regulator complement(1375222..1376415) Escherichia coli O104:H4 str. 2011C-3493 13702788 YP_006778042.1 CDS O3K_06670 NC_018658.1 1376533 1379814 D COG0457 FOG: TPR repeat; hypothetical protein 1376533..1379814 Escherichia coli O104:H4 str. 2011C-3493 13702789 YP_006778043.1 CDS O3K_06675 NC_018658.1 1379911 1380894 D COG1879 ABC-type sugar transport system, periplasmic component; sugar ABC transporter substrate-binding protein 1379911..1380894 Escherichia coli O104:H4 str. 2011C-3493 13702790 YP_006778044.1 CDS O3K_06680 NC_018658.1 1380917 1382428 D COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein 1380917..1382428 Escherichia coli O104:H4 str. 2011C-3493 13702791 YP_006778045.1 CDS O3K_06685 NC_018658.1 1382453 1383451 D COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar transporter subunit 1382453..1383451 Escherichia coli O104:H4 str. 2011C-3493 13702792 YP_006778046.1 CDS O3K_06690 NC_018658.1 1383517 1384578 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein 1383517..1384578 Escherichia coli O104:H4 str. 2011C-3493 13702793 YP_006778047.1 CDS O3K_06695 NC_018658.1 1384590 1385462 D COG2017 Galactose mutarotase and related enzymes; hypothetical protein 1384590..1385462 Escherichia coli O104:H4 str. 2011C-3493 13702794 YP_006778048.1 CDS O3K_06700 NC_018658.1 1385510 1385932 R COG2259 Predicted membrane protein; inner membrane protein complement(1385510..1385932) Escherichia coli O104:H4 str. 2011C-3493 13702795 YP_006778049.1 CDS O3K_06705 NC_018658.1 1386029 1387231 R COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; phenylpropionate dioxygenase ferredoxin reductase subunit complement(1386029..1387231) Escherichia coli O104:H4 str. 2011C-3493 13702796 YP_006778050.1 CDS O3K_06710 NC_018658.1 1387241 1388053 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase complement(1387241..1388053) Escherichia coli O104:H4 str. 2011C-3493 13702797 YP_006778051.1 CDS O3K_06715 NC_018658.1 1388050 1388370 R COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; 3-phenylpropionate dioxygenase ferredoxin subunit complement(1388050..1388370) Escherichia coli O104:H4 str. 2011C-3493 13702798 YP_006778052.1 CDS O3K_06720 NC_018658.1 1388370 1388888 R COG5517 Small subunit of phenylpropionate dioxygenase; 3-phenylpropionate dioxygenase subunit beta complement(1388370..1388888) Escherichia coli O104:H4 str. 2011C-3493 13702799 YP_006778053.1 CDS O3K_06725 NC_018658.1 1388885 1390246 R COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha complement(1388885..1390246) Escherichia coli O104:H4 str. 2011C-3493 13702800 YP_006778054.1 CDS O3K_06730 NC_018658.1 1390382 1391272 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator HcaR 1390382..1391272 Escherichia coli O104:H4 str. 2011C-3493 13702801 YP_006778055.1 CDS O3K_06735 NC_018658.1 1391432 1392571 D COG0477 Permeases of the major facilitator superfamily; putative 3-phenylpropionic acid transporter 1391432..1392571 Escherichia coli O104:H4 str. 2011C-3493 13702802 YP_006778056.1 CDS O3K_06740 NC_018658.1 1392563 1393843 R COG3711 Transcriptional antiterminator; stationary phase inducible protein CsiE complement(1392563..1393843) Escherichia coli O104:H4 str. 2011C-3493 13702803 YP_006778057.1 CDS O3K_06745 NC_018658.1 1394034 1394888 R COG1073 Hydrolases of the alpha/beta superfamily; peptidase complement(1394034..1394888) Escherichia coli O104:H4 str. 2011C-3493 13702804 YP_006778058.1 CDS O3K_06750 NC_018658.1 1395033 1395836 R COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; inositol monophosphatase complement(1395033..1395836) Escherichia coli O104:H4 str. 2011C-3493 13702805 YP_006778059.1 CDS O3K_06755 NC_018658.1 1395955 1396695 D COG0565 rRNA methylase; tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ 1395955..1396695 Escherichia coli O104:H4 str. 2011C-3493 13702806 YP_006778060.1 CDS O3K_06760 NC_018658.1 1396965 1397453 D COG1959 Predicted transcriptional regulator; DNA-binding transcriptional regulator IscR 1396965..1397453 Escherichia coli O104:H4 str. 2011C-3493 13702807 YP_006778061.1 CDS O3K_06765 NC_018658.1 1397565 1398779 D COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine desulfurase 1397565..1398779 Escherichia coli O104:H4 str. 2011C-3493 13702808 YP_006778062.1 CDS O3K_06770 NC_018658.1 1398807 1399193 D COG0822 NifU homolog involved in Fe-S cluster formation; scaffold protein 1398807..1399193 Escherichia coli O104:H4 str. 2011C-3493 13702809 YP_006778063.1 CDS iscA NC_018658.1 1399210 1399533 D COG0316 Uncharacterized conserved protein; iron-sulfur cluster assembly protein 1399210..1399533 Escherichia coli O104:H4 str. 2011C-3493 13702810 YP_006778064.1 CDS hscB NC_018658.1 1399629 1400144 D COG1076 DnaJ-domain-containing proteins 1; co-chaperone HscB 1399629..1400144 Escherichia coli O104:H4 str. 2011C-3493 13702811 YP_006778065.1 CDS hscA NC_018658.1 1400161 1402011 D COG0443 Molecular chaperone; chaperone protein HscA 1400161..1402011 Escherichia coli O104:H4 str. 2011C-3493 13702812 YP_006778066.1 CDS O3K_06790 NC_018658.1 1402013 1402348 D COG0633 Ferredoxin; 2Fe-2S ferredoxin 1402013..1402348 Escherichia coli O104:H4 str. 2011C-3493 13702813 YP_006778067.1 CDS O3K_06795 NC_018658.1 1402360 1402560 D COG2975 Uncharacterized protein conserved in bacteria; hypothetical protein 1402360..1402560 Escherichia coli O104:H4 str. 2011C-3493 13702814 YP_006778068.1 CDS O3K_06800 NC_018658.1 1402738 1404021 D COG0260 Leucyl aminopeptidase; aminopeptidase B 1402738..1404021 Escherichia coli O104:H4 str. 2011C-3493 13702815 YP_006778069.1 CDS O3K_06805 NC_018658.1 1404163 1404939 D enhanced serine sensitivity protein SseB 1404163..1404939 Escherichia coli O104:H4 str. 2011C-3493 13702816 YP_006778070.1 CDS sseA NC_018658.1 1405432 1406277 R COG2897 Rhodanese-related sulfurtransferase; 3-mercaptopyruvate sulfurtransferase complement(1405432..1406277) Escherichia coli O104:H4 str. 2011C-3493 13702817 YP_006778071.1 CDS O3K_06815 NC_018658.1 1406484 1411445 D COG2373 Large extracellular alpha-helical protein; hypothetical protein 1406484..1411445 Escherichia coli O104:H4 str. 2011C-3493 13702818 YP_006778072.1 CDS O3K_06820 NC_018658.1 1411446 1413758 D COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; penicillin-binding protein 1C 1411446..1413758 Escherichia coli O104:H4 str. 2011C-3493 13702819 YP_006778073.1 CDS ndk NC_018658.1 1413907 1414338 D COG0105 Nucleoside diphosphate kinase; mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase 1413907..1414338 Escherichia coli O104:H4 str. 2011C-3493 13702820 YP_006778074.1 CDS O3K_06830 NC_018658.1 1414488 1415642 D COG0820 Predicted Fe-S-cluster redox enzyme; ribosomal RNA large subunit methyltransferase N 1414488..1415642 Escherichia coli O104:H4 str. 2011C-3493 13702821 YP_006778075.1 CDS O3K_06835 NC_018658.1 1415927 1416940 D COG1426 Uncharacterized protein conserved in bacteria; cytoskeletal protein RodZ 1415927..1416940 Escherichia coli O104:H4 str. 2011C-3493 13702822 YP_006778076.1 CDS ispG NC_018658.1 1416967 1418085 D COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1416967..1418085 Escherichia coli O104:H4 str. 2011C-3493 13702823 YP_006778077.1 CDS hisS NC_018658.1 1418196 1419470 D COG0124 Histidyl-tRNA synthetase; histidyl-tRNA synthetase 1418196..1419470 Escherichia coli O104:H4 str. 2011C-3493 13702824 YP_006778078.1 CDS O3K_06850 NC_018658.1 1419488 1420108 D COG2976 Uncharacterized protein conserved in bacteria; hypothetical protein 1419488..1420108 Escherichia coli O104:H4 str. 2011C-3493 13702825 YP_006778079.1 CDS O3K_06855 NC_018658.1 1420119 1421297 D COG1520 FOG: WD40-like repeat; outer membrane biogenesis protein BamB 1420119..1421297 Escherichia coli O104:H4 str. 2011C-3493 13702826 YP_006778080.1 CDS O3K_06860 NC_018658.1 1421415 1422887 D COG1160 Predicted GTPases; GTP-binding protein Der 1421415..1422887 Escherichia coli O104:H4 str. 2011C-3493 13702827 YP_006778081.1 CDS O3K_06865 NC_018658.1 1422956 1423171 D COG1933 Archaeal DNA polymerase II, large subunit; hypothetical protein 1422956..1423171 Escherichia coli O104:H4 str. 2011C-3493 13702828 YP_006778082.1 CDS xseA NC_018658.1 1423168 1424538 R COG1570 Exonuclease VII, large subunit; exodeoxyribonuclease VII large subunit complement(1423168..1424538) Escherichia coli O104:H4 str. 2011C-3493 13702829 YP_006778083.1 CDS O3K_06875 NC_018658.1 1424700 1426166 D COG0516 IMP dehydrogenase/GMP reductase; inosine 5'-monophosphate dehydrogenase 1424700..1426166 Escherichia coli O104:H4 str. 2011C-3493 13702830 YP_006778084.1 CDS guaA NC_018658.1 1426235 1427812 D COG0518 GMP synthase - Glutamine amidotransferase domain; GMP synthase 1426235..1427812 Escherichia coli O104:H4 str. 2011C-3493 13702831 YP_006778085.1 CDS O3K_06885 NC_018658.1 1427905 1428444 R hypothetical protein complement(1427905..1428444) Escherichia coli O104:H4 str. 2011C-3493 13702832 YP_006778086.1 CDS O3K_06890 NC_018658.1 1428460 1428978 R putative outer membrane lipoprotein complement(1428460..1428978) Escherichia coli O104:H4 str. 2011C-3493 13702833 YP_006778087.1 CDS O3K_06895 NC_018658.1 1429289 1429480 R hypothetical protein complement(1429289..1429480) Escherichia coli O104:H4 str. 2011C-3493 13702834 YP_006778088.1 CDS O3K_06900 NC_018658.1 1429498 1429650 D hypothetical protein 1429498..1429650 Escherichia coli O104:H4 str. 2011C-3493 13702835 YP_006778089.1 CDS O3K_06905 NC_018658.1 1429832 1432075 D COG2199 FOG: GGDEF domain; inner membrane protein 1429832..1432075 Escherichia coli O104:H4 str. 2011C-3493 13702836 YP_006778090.1 CDS O3K_06910 NC_018658.1 1432114 1433655 R COG0248 Exopolyphosphatase; exopolyphosphatase complement(1432114..1433655) Escherichia coli O104:H4 str. 2011C-3493 13702837 YP_006778091.1 CDS O3K_06915 NC_018658.1 1433660 1435726 R COG0855 Polyphosphate kinase; polyphosphate kinase complement(1433660..1435726) Escherichia coli O104:H4 str. 2011C-3493 13702838 YP_006778092.1 CDS purN NC_018658.1 1435897 1436535 R COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; phosphoribosylglycinamide formyltransferase complement(1435897..1436535) Escherichia coli O104:H4 str. 2011C-3493 13702839 YP_006778093.1 CDS O3K_06925 NC_018658.1 1436535 1437572 R COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; phosphoribosylaminoimidazole synthetase complement(1436535..1437572) Escherichia coli O104:H4 str. 2011C-3493 13702840 YP_006778094.1 CDS upp NC_018658.1 1437897 1438523 D COG0035 Uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 1437897..1438523 Escherichia coli O104:H4 str. 2011C-3493 13702841 YP_006778095.1 CDS O3K_06935 NC_018658.1 1438609 1439898 D COG2233 Xanthine/uracil permeases; uracil transporter 1438609..1439898 Escherichia coli O104:H4 str. 2011C-3493 13702842 YP_006778096.1 CDS O3K_06940 NC_018658.1 1439948 1440694 D COG0593 ATPase involved in DNA replication initiation; DNA replication initiation factor 1439948..1440694 Escherichia coli O104:H4 str. 2011C-3493 13702843 YP_006778097.1 CDS O3K_06945 NC_018658.1 1440832 1441191 R COG1393 Arsenate reductase and related proteins, glutaredoxin family; oxidoreductase complement(1440832..1441191) Escherichia coli O104:H4 str. 2011C-3493 13702844 YP_006778098.1 CDS O3K_06950 NC_018658.1 1441212 1442675 R COG4783 Putative Zn-dependent protease, contains TPR repeats; peptidase, M48 family protein complement(1441212..1442675) Escherichia coli O104:H4 str. 2011C-3493 13702845 YP_006778099.1 CDS O3K_06955 NC_018658.1 1442888 1443949 D COG0628 Predicted permease; permease perM 1442888..1443949 Escherichia coli O104:H4 str. 2011C-3493 13702846 YP_006778100.1 CDS O3K_06960 NC_018658.1 1444103 1444834 R COG2116 Formate/nitrite family of transporters; formate transporter complement(1444103..1444834) Escherichia coli O104:H4 str. 2011C-3493 13702847 YP_006778101.1 CDS O3K_06965 NC_018658.1 1444856 1446868 R COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; DNA-binding transcriptional activator, formate sensing complement(1444856..1446868) Escherichia coli O104:H4 str. 2011C-3493 13702848 YP_006778102.1 CDS O3K_06970 NC_018658.1 1446898 1447311 R formate hydrogenlyase maturation protein HycH complement(1446898..1447311) Escherichia coli O104:H4 str. 2011C-3493 13702849 YP_006778103.1 CDS O3K_06975 NC_018658.1 1447304 1448062 R COG3260 Ni,Fe-hydrogenase III small subunit; hydrogenase 4, Fe-S subunit complement(1447304..1448062) Escherichia coli O104:H4 str. 2011C-3493 13702850 YP_006778104.1 CDS O3K_06980 NC_018658.1 1448059 1448598 R COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); hydrogenase 4 subunit H complement(1448059..1448598) Escherichia coli O104:H4 str. 2011C-3493 13702851 YP_006778105.1 CDS O3K_06985 NC_018658.1 1448608 1450323 R COG3262 Ni,Fe-hydrogenase III component G; hydrogenase 4 membrane subunit complement(1448608..1450323) Escherichia coli O104:H4 str. 2011C-3493 13702852 YP_006778106.1 CDS O3K_06990 NC_018658.1 1450313 1451893 R COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hydrogenase 4 subunit F complement(1450313..1451893) Escherichia coli O104:H4 str. 2011C-3493 13702853 YP_006778107.1 CDS hyfE NC_018658.1 1451898 1452548 R COG4237 Hydrogenase 4 membrane component (E); hydrogenase 4 membrane subunit complement(1451898..1452548) Escherichia coli O104:H4 str. 2011C-3493 13702854 YP_006778108.1 CDS O3K_07000 NC_018658.1 1452560 1453546 R COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; hydrogenase 4 subunit D complement(1452560..1453546) Escherichia coli O104:H4 str. 2011C-3493 13702855 YP_006778109.1 CDS O3K_07005 NC_018658.1 1453543 1453998 R COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; putative hydrogenase 4 membrane subunit complement(1453543..1453998) Escherichia coli O104:H4 str. 2011C-3493 13702856 YP_006778110.1 CDS O3K_07010 NC_018658.1 1454015 1454149 R hydrogenase 4 membrane subunit complement(1454015..1454149) Escherichia coli O104:H4 str. 2011C-3493 13702857 YP_006778111.1 CDS O3K_07015 NC_018658.1 1454204 1454962 R COG0650 Formate hydrogenlyase subunit 4; hydrogenase 4 membrane subunit complement(1454204..1454962) Escherichia coli O104:H4 str. 2011C-3493 13702858 YP_006778112.1 CDS O3K_07020 NC_018658.1 1454973 1456991 R COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hydrogenase 4 subunit B complement(1454973..1456991) Escherichia coli O104:H4 str. 2011C-3493 13702859 YP_006778113.1 CDS O3K_07025 NC_018658.1 1456991 1457608 R COG1142 Fe-S-cluster-containing hydrogenase components 2; hydrogenase 4, 4Fe-4S subunit complement(1456991..1457608) Escherichia coli O104:H4 str. 2011C-3493 13702860 YP_006778114.1 CDS bcp NC_018658.1 1457861 1458331 R COG1225 Peroxiredoxin; thioredoxin-dependent thiol peroxidase complement(1457861..1458331) Escherichia coli O104:H4 str. 2011C-3493 13702861 YP_006778115.1 CDS gcvR NC_018658.1 1458331 1458903 R COG2716 Glycine cleavage system regulatory protein; glycine cleavage system transcriptional repressor complement(1458331..1458903) Escherichia coli O104:H4 str. 2011C-3493 13702862 YP_006778116.1 CDS O3K_07040 NC_018658.1 1459049 1459927 D COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase 1459049..1459927 Escherichia coli O104:H4 str. 2011C-3493 13702863 YP_006778117.1 CDS O3K_07045 NC_018658.1 1459944 1460978 D COG3317 Uncharacterized lipoprotein; lipoprotein 1459944..1460978 Escherichia coli O104:H4 str. 2011C-3493 13702864 YP_006778118.1 CDS O3K_07050 NC_018658.1 1460889 1461140 R hypothetical protein complement(1460889..1461140) Escherichia coli O104:H4 str. 2011C-3493 13702865 YP_006778119.1 CDS O3K_07055 NC_018658.1 1461191 1461904 D COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 1461191..1461904 Escherichia coli O104:H4 str. 2011C-3493 13702866 YP_006778120.1 CDS O3K_07060 NC_018658.1 1462059 1462286 D COG4456 Virulence-associated protein and related proteins; transcriptional regulation protein 1462059..1462286 Escherichia coli O104:H4 str. 2011C-3493 13702867 YP_006778121.1 CDS O3K_07065 NC_018658.1 1462286 1462684 D COG1487 Predicted nucleic acid-binding protein, contains PIN domain; plasmid maintenance protein 1462286..1462684 Escherichia coli O104:H4 str. 2011C-3493 13702868 YP_006778122.1 CDS O3K_07070 NC_018658.1 1462831 1463694 D COG2321 Predicted metalloprotease; hypothetical protein 1462831..1463694 Escherichia coli O104:H4 str. 2011C-3493 13702869 YP_006778123.1 CDS O3K_07075 NC_018658.1 1463709 1465724 D COG1444 Predicted P-loop ATPase fused to an acetyltransferase; hydrolase 1463709..1465724 Escherichia coli O104:H4 str. 2011C-3493 13702870 YP_006778124.1 CDS O3K_07080 NC_018658.1 1465798 1466496 D COG0400 Predicted esterase; hydrolase 1465798..1466496 Escherichia coli O104:H4 str. 2011C-3493 13702871 YP_006778125.1 CDS O3K_07085 NC_018658.1 1466606 1466806 R hypothetical protein complement(1466606..1466806) Escherichia coli O104:H4 str. 2011C-3493 13702872 YP_006778126.1 CDS O3K_07090 NC_018658.1 1466834 1467961 R COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; succinyl-diaminopimelate desuccinylase complement(1466834..1467961) Escherichia coli O104:H4 str. 2011C-3493 13702873 YP_006778127.1 CDS O3K_07095 NC_018658.1 1467965 1468321 R COG1393 Arsenate reductase and related proteins, glutaredoxin family; putative reductase complement(1467965..1468321) Escherichia coli O104:H4 str. 2011C-3493 13702874 YP_006778128.1 CDS O3K_07100 NC_018658.1 1468860 1471973 R COG0841 Cation/multidrug efflux pump; aminoglycoside/multidrug efflux system complement(1468860..1471973) Escherichia coli O104:H4 str. 2011C-3493 13702875 YP_006778129.1 CDS O3K_07105 NC_018658.1 1472137 1473837 R COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific; nitrate/nitrite sensor protein NarQ complement(1472137..1473837) Escherichia coli O104:H4 str. 2011C-3493 13702876 YP_006778130.1 CDS O3K_07110 NC_018658.1 1474043 1476022 D COG1142 Fe-S-cluster-containing hydrogenase components 2; putative oxidoreductase Fe-S binding subunit 1474043..1476022 Escherichia coli O104:H4 str. 2011C-3493 13702877 YP_006778131.1 CDS O3K_07115 NC_018658.1 1476090 1476665 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; GDP-mannose pyrophosphatase NudK 1476090..1476665 Escherichia coli O104:H4 str. 2011C-3493 13702878 YP_006778132.1 CDS O3K_07120 NC_018658.1 1476791 1477834 D COG1088 dTDP-D-glucose 4,6-dehydratase; hypothetical protein 1476791..1477834 Escherichia coli O104:H4 str. 2011C-3493 13702879 YP_006778133.1 CDS O3K_07125 NC_018658.1 1477930 1479933 R COG0021 Transketolase; transketolase complement(1477930..1479933) Escherichia coli O104:H4 str. 2011C-3493 13702880 YP_006778134.1 CDS O3K_07130 NC_018658.1 1479953 1480903 R COG0176 Transaldolase; transaldolase A complement(1479953..1480903) Escherichia coli O104:H4 str. 2011C-3493 13702881 YP_006778135.1 CDS O3K_07135 NC_018658.1 1481192 1483471 D COG0281 Malic enzyme; bifunctional malic enzyme oxidoreductase/phosphotransacetylase 1481192..1483471 Escherichia coli O104:H4 str. 2011C-3493 13702882 YP_006778136.1 CDS O3K_07140 NC_018658.1 1483764 1484099 D COG4810 Ethanolamine utilization protein; carboxysome structural protein EutS 1483764..1484099 Escherichia coli O104:H4 str. 2011C-3493 13702883 YP_006778137.1 CDS O3K_07145 NC_018658.1 1484112 1484591 D COG4917 Ethanolamine utilization protein; ethanolamine utilization protein EutP 1484112..1484591 Escherichia coli O104:H4 str. 2011C-3493 13702884 YP_006778138.1 CDS O3K_07150 NC_018658.1 1484566 1485267 D COG4766 Ethanolamine utilization protein; ethanolamine utilization protein EutQ 1484566..1485267 Escherichia coli O104:H4 str. 2011C-3493 13702885 YP_006778139.1 CDS O3K_07155 NC_018658.1 1485264 1486067 D COG4812 Ethanolamine utilization cobalamin adenosyltransferase; ethanolamine utilization cobalamin adenosyltransferase 1485264..1486067 Escherichia coli O104:H4 str. 2011C-3493 13702886 YP_006778140.1 CDS eutD NC_018658.1 1486064 1487080 D COG0280 Phosphotransacetylase; phosphotransacetylase 1486064..1487080 Escherichia coli O104:H4 str. 2011C-3493 13702887 YP_006778141.1 CDS O3K_07165 NC_018658.1 1487119 1487412 D COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; carboxysome structural protein EutM 1487119..1487412 Escherichia coli O104:H4 str. 2011C-3493 13702888 YP_006778142.1 CDS O3K_07170 NC_018658.1 1487519 1487806 D COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein; ethanolamine catabolic microcompartment shell protein EutN 1487519..1487806 Escherichia coli O104:H4 str. 2011C-3493 13702889 YP_006778143.1 CDS O3K_07175 NC_018658.1 1487818 1489221 D COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase EutE 1487818..1489221 Escherichia coli O104:H4 str. 2011C-3493 13702890 YP_006778144.1 CDS O3K_07180 NC_018658.1 1489232 1490068 D COG4820 Ethanolamine utilization protein, possible chaperonin; ethanolamine utilization protein EutJ 1489232..1490068 Escherichia coli O104:H4 str. 2011C-3493 13702891 YP_006778145.1 CDS O3K_07185 NC_018658.1 1490058 1491245 D COG1454 Alcohol dehydrogenase, class IV; ethanol dehydrogenase EutG 1490058..1491245 Escherichia coli O104:H4 str. 2011C-3493 13702892 YP_006778146.1 CDS O3K_07190 NC_018658.1 1491562 1492788 D COG3192 Ethanolamine utilization protein; ethanolamine utilization protein EutH 1491562..1492788 Escherichia coli O104:H4 str. 2011C-3493 13702893 YP_006778147.1 CDS eutA NC_018658.1 1492785 1494188 D COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition; reactivating factor for ethanolamine ammonia lyase 1492785..1494188 Escherichia coli O104:H4 str. 2011C-3493 13702894 YP_006778148.1 CDS O3K_07200 NC_018658.1 1494200 1495561 D COG4303 Ethanolamine ammonia-lyase, large subunit; ethanolamine ammonia lyase large subunit 1494200..1495561 Escherichia coli O104:H4 str. 2011C-3493 13702895 YP_006778149.1 CDS O3K_07205 NC_018658.1 1495582 1496469 D COG4302 Ethanolamine ammonia-lyase, small subunit; ethanolamine ammonia-lyase small subunit 1495582..1496469 Escherichia coli O104:H4 str. 2011C-3493 13702896 YP_006778150.1 CDS O3K_07210 NC_018658.1 1496479 1497138 D COG4816 Ethanolamine utilization protein; ethanolamine utilization protein EutL 1496479..1497138 Escherichia coli O104:H4 str. 2011C-3493 13702897 YP_006778151.1 CDS O3K_07215 NC_018658.1 1497151 1497651 D COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; carboxysome structural protein EutK 1497151..1497651 Escherichia coli O104:H4 str. 2011C-3493 13702898 YP_006778152.1 CDS O3K_07220 NC_018658.1 1497697 1498749 D COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator EutR 1497697..1498749 Escherichia coli O104:H4 str. 2011C-3493 13702899 YP_006778153.1 CDS O3K_07225 NC_018658.1 1498755 1499654 R COG0408 Coproporphyrinogen III oxidase; coproporphyrinogen III oxidase complement(1498755..1499654) Escherichia coli O104:H4 str. 2011C-3493 13702900 YP_006778154.1 CDS O3K_07230 NC_018658.1 1499658 1500527 R COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-l-alanine amidase I complement(1499658..1500527) Escherichia coli O104:H4 str. 2011C-3493 13702901 YP_006778155.1 CDS O3K_07235 NC_018658.1 1500741 1501166 D COG0456 Acetyltransferases; acetyltransferase 1500741..1501166 Escherichia coli O104:H4 str. 2011C-3493 13702902 YP_006778156.1 CDS O3K_07240 NC_018658.1 1501153 1501602 D inner membrane protein 1501153..1501602 Escherichia coli O104:H4 str. 2011C-3493 13702903 YP_006778157.1 CDS O3K_07245 NC_018658.1 1501663 1502238 D RpoE-regulated lipoprotein 1501663..1502238 Escherichia coli O104:H4 str. 2011C-3493 13702904 YP_006778158.1 CDS O3K_07250 NC_018658.1 1502334 1503233 D COG2837 Predicted iron-dependent peroxidase; dyp-type peroxidase family protein 1502334..1503233 Escherichia coli O104:H4 str. 2011C-3493 13702905 YP_006778159.1 CDS O3K_07255 NC_018658.1 1503289 1504593 R COG1680 Beta-lactamase class C and other penicillin binding proteins; putative periplasmic esterase complement(1503289..1504593) Escherichia coli O104:H4 str. 2011C-3493 13702906 YP_006778160.1 CDS murP NC_018658.1 1504598 1506022 R COG1264 Phosphotransferase system IIB components; PTS system N-acetylmuramic acid transporter subunit IIBC complement(1504598..1506022) Escherichia coli O104:H4 str. 2011C-3493 13702907 YP_006778161.1 CDS murQ NC_018658.1 1506026 1506922 R COG2103 Predicted sugar phosphate isomerase; N-acetylmuramic acid 6-phosphate etherase complement(1506026..1506922) Escherichia coli O104:H4 str. 2011C-3493 13702908 YP_006778162.1 CDS O3K_07270 NC_018658.1 1507086 1507943 D COG1737 Transcriptional regulators; transcriptional regulator MurR 1507086..1507943 Escherichia coli O104:H4 str. 2011C-3493 13702909 YP_006778163.1 CDS O3K_07275 NC_018658.1 1508072 1508863 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 1508072..1508863 Escherichia coli O104:H4 str. 2011C-3493 13702910 YP_006778164.1 CDS O3K_07280 NC_018658.1 1509034 1510050 D COG4150 ABC-type sulfate transport system, periplasmic component; thiosulfate transporter subunit 1509034..1510050 Escherichia coli O104:H4 str. 2011C-3493 13702911 YP_006778165.1 CDS O3K_07285 NC_018658.1 1510050 1510883 D COG0555 ABC-type sulfate transport system, permease component; sulfate/thiosulfate transporter subunit 1510050..1510883 Escherichia coli O104:H4 str. 2011C-3493 13702912 YP_006778166.1 CDS cysW NC_018658.1 1510883 1511758 D COG4208 ABC-type sulfate transport system, permease component; sulfate/thiosulfate transporter permease subunit 1510883..1511758 Escherichia coli O104:H4 str. 2011C-3493 13702913 YP_006778167.1 CDS O3K_07295 NC_018658.1 1511748 1512845 D COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; sulfate/thiosulfate transporter subunit 1511748..1512845 Escherichia coli O104:H4 str. 2011C-3493 13702914 YP_006778168.1 CDS cysM NC_018658.1 1512979 1513890 D COG0031 Cysteine synthase; cysteine synthase B 1512979..1513890 Escherichia coli O104:H4 str. 2011C-3493 13702915 YP_006778169.1 CDS O3K_07305 NC_018658.1 1513893 1514261 R hypothetical protein complement(1513893..1514261) Escherichia coli O104:H4 str. 2011C-3493 13702916 YP_006778170.1 CDS pdxK NC_018658.1 1514366 1515217 D COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase 1514366..1515217 Escherichia coli O104:H4 str. 2011C-3493 13702917 YP_006778171.1 CDS O3K_07315 NC_018658.1 1515259 1515768 R COG2190 Phosphotransferase system IIA components; PTS system glucose-specific transporter complement(1515259..1515768) Escherichia coli O104:H4 str. 2011C-3493 13702918 YP_006778172.1 CDS O3K_07320 NC_018658.1 1515809 1517536 R COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); phosphoenolpyruvate-protein phosphotransferase complement(1515809..1517536) Escherichia coli O104:H4 str. 2011C-3493 13702919 YP_006778173.1 CDS O3K_07325 NC_018658.1 1517581 1517838 R COG1925 Phosphotransferase system, HPr-related proteins; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr complement(1517581..1517838) Escherichia coli O104:H4 str. 2011C-3493 13702920 YP_006778174.1 CDS O3K_07330 NC_018658.1 1518222 1519193 R COG0031 Cysteine synthase; cysteine synthase A complement(1518222..1519193) Escherichia coli O104:H4 str. 2011C-3493 13702921 YP_006778175.1 CDS O3K_07335 NC_018658.1 1519378 1520139 R COG2981 Uncharacterized protein involved in cysteine biosynthesis; putative sulfate transport protein CysZ complement(1519378..1520139) Escherichia coli O104:H4 str. 2011C-3493 13702922 YP_006778176.1 CDS O3K_07340 NC_018658.1 1520369 1521355 D COG3115 Cell division protein; cell division protein ZipA 1520369..1521355 Escherichia coli O104:H4 str. 2011C-3493 13702923 YP_006778177.1 CDS ligA NC_018658.1 1521426 1523441 D COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase LigA 1521426..1523441 Escherichia coli O104:H4 str. 2011C-3493 13702924 YP_006778178.1 CDS O3K_07350 NC_018658.1 1523443 1523661 D COG3530 Uncharacterized protein conserved in bacteria; hypothetical protein 1523443..1523661 Escherichia coli O104:H4 str. 2011C-3493 13702925 YP_006778179.1 CDS O3K_07355 NC_018658.1 1523658 1524656 R COG0385 Predicted Na+-dependent transporter; hypothetical protein complement(1523658..1524656) Escherichia coli O104:H4 str. 2011C-3493 13702926 YP_006778180.1 CDS O3K_07360 NC_018658.1 1524746 1525672 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 1524746..1525672 Escherichia coli O104:H4 str. 2011C-3493 13702927 YP_006778181.1 CDS O3K_07365 NC_018658.1 1525711 1526475 R hypothetical protein complement(1525711..1526475) Escherichia coli O104:H4 str. 2011C-3493 13702928 YP_006778182.1 CDS O3K_07370 NC_018658.1 1526724 1527557 D COG0005 Purine nucleoside phosphorylase; purine nucleoside phosphorylase 1526724..1527557 Escherichia coli O104:H4 str. 2011C-3493 13702929 YP_006778183.1 CDS O3K_07375 NC_018658.1 1527617 1528873 D COG0477 Permeases of the major facilitator superfamily; xanthosine transporter 1527617..1528873 Escherichia coli O104:H4 str. 2011C-3493 13702930 YP_006778184.1 CDS O3K_07380 NC_018658.1 1528926 1529084 D hypothetical protein 1528926..1529084 Escherichia coli O104:H4 str. 2011C-3493 13702931 YP_006778185.1 CDS O3K_07385 NC_018658.1 1529125 1530009 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator XapR 1529125..1530009 Escherichia coli O104:H4 str. 2011C-3493 13702932 YP_006778186.1 CDS gltX NC_018658.1 1530930 1532345 D COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-tRNA synthetase 1530930..1532345 Escherichia coli O104:H4 str. 2011C-3493 13702937 YP_006778187.1 CDS O3K_07395 NC_018658.1 1532397 1532789 R COG1396 Predicted transcriptional regulators; putative DNA-binding transcriptional regulator complement(1532397..1532789) Escherichia coli O104:H4 str. 2011C-3493 13702938 YP_006778188.1 CDS O3K_07400 NC_018658.1 1532791 1533150 R hypothetical protein complement(1532791..1533150) Escherichia coli O104:H4 str. 2011C-3493 13702939 YP_006778189.1 CDS O3K_07405 NC_018658.1 1533769 1535958 D COG2199 FOG: GGDEF domain; diguanylate cyclase 1533769..1535958 Escherichia coli O104:H4 str. 2011C-3493 13702942 YP_006778190.1 CDS O3K_07410 NC_018658.1 1536008 1537210 R COG1972 Nucleoside permease; nucleoside (except guanosine) transporter NupC complement(1536008..1537210) Escherichia coli O104:H4 str. 2011C-3493 13702943 YP_006778191.1 CDS O3K_07415 NC_018658.1 1537546 1538784 D COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; manganese transport protein MntH 1537546..1538784 Escherichia coli O104:H4 str. 2011C-3493 13702944 YP_006778192.1 CDS O3K_07420 NC_018658.1 1538925 1539251 R hypothetical protein complement(1538925..1539251) Escherichia coli O104:H4 str. 2011C-3493 13702945 YP_006778193.1 CDS O3K_07425 NC_018658.1 1539366 1540622 R COG1284 Uncharacterized conserved protein; putative ion channel protein complement(1539366..1540622) Escherichia coli O104:H4 str. 2011C-3493 13702946 YP_006778194.1 CDS glk NC_018658.1 1540826 1541791 D COG0837 Glucokinase; glucokinase 1540826..1541791 Escherichia coli O104:H4 str. 2011C-3493 13702947 YP_006778195.1 CDS O3K_07435 NC_018658.1 1542010 1542336 D COG1445 Phosphotransferase system fructose-specific component IIB; PTS system transporter subunit IIB 1542010..1542336 Escherichia coli O104:H4 str. 2011C-3493 13702948 YP_006778196.1 CDS O3K_07440 NC_018658.1 1542358 1543605 D COG1299 Phosphotransferase system, fructose-specific IIC component; fructose-like permease IIC component 1542358..1543605 Escherichia coli O104:H4 str. 2011C-3493 13702949 YP_006778197.1 CDS O3K_07445 NC_018658.1 1543620 1544705 D COG0006 Xaa-Pro aminopeptidase; aminopeptidase 1543620..1544705 Escherichia coli O104:H4 str. 2011C-3493 13702950 YP_006778198.1 CDS O3K_07450 NC_018658.1 1544705 1545742 D COG1363 Cellulase M and related proteins; exoaminopeptidase 1544705..1545742 Escherichia coli O104:H4 str. 2011C-3493 13702951 YP_006778199.1 CDS O3K_07455 NC_018658.1 1545767 1548262 D multiphosphoryl transfer protein; COG1925 Phosphotransferase system, HPr-related proteins; PTS system transporter proteins Hpr/EI/IIA 1545767..1548262 Escherichia coli O104:H4 str. 2011C-3493 13702952 YP_006778200.1 CDS O3K_07460 NC_018658.1 1548265 1549122 R COG2207 AraC-type DNA-binding domain-containing proteins; putative DNA-binding protein, ARAC-type complement(1548265..1549122) Escherichia coli O104:H4 str. 2011C-3493 13702953 YP_006778201.1 CDS O3K_07465 NC_018658.1 1549135 1549869 R COG3279 Response regulator of the LytR/AlgR family; hypothetical protein complement(1549135..1549869) Escherichia coli O104:H4 str. 2011C-3493 13702954 YP_006778202.1 CDS O3K_07470 NC_018658.1 1549884 1551581 R COG3275 Putative regulator of cell autolysis; hypothetical protein complement(1549884..1551581) Escherichia coli O104:H4 str. 2011C-3493 13702955 YP_006778203.1 CDS O3K_07475 NC_018658.1 1551958 1553196 D COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase 1551958..1553196 Escherichia coli O104:H4 str. 2011C-3493 13702956 YP_006778204.1 CDS O3K_07480 NC_018658.1 1553688 1554608 R COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis palmitoleoyl acyltransferase complement(1553688..1554608) Escherichia coli O104:H4 str. 2011C-3493 13702957 YP_006778205.1 CDS O3K_07485 NC_018658.1 1554961 1555203 D inner membrane protein 1554961..1555203 Escherichia coli O104:H4 str. 2011C-3493 13702958 YP_006778206.1 CDS O3K_07490 NC_018658.1 1555280 1555555 R lipoprotein complement(1555280..1555555) Escherichia coli O104:H4 str. 2011C-3493 13702959 YP_006778207.1 CDS O3K_07495 NC_018658.1 1555851 1556483 D hypothetical protein 1555851..1556483 Escherichia coli O104:H4 str. 2011C-3493 13702960 YP_006778208.1 CDS O3K_07500 NC_018658.1 1556996 1558246 D COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; formyl-coenzyme A transferase 1556996..1558246 Escherichia coli O104:H4 str. 2011C-3493 13702961 YP_006778209.1 CDS O3K_07505 NC_018658.1 1558300 1559994 D COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; putative oxalyl-CoA decarboxylase 1558300..1559994 Escherichia coli O104:H4 str. 2011C-3493 13702962 YP_006778210.1 CDS O3K_07510 NC_018658.1 1560064 1561008 D COG0679 Predicted permeases; putative transporter YfdV 1560064..1561008 Escherichia coli O104:H4 str. 2011C-3493 13702963 YP_006778211.1 CDS O3K_07515 NC_018658.1 1561082 1562227 D COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; putative CoA-transferase 1561082..1562227 Escherichia coli O104:H4 str. 2011C-3493 13702964 YP_006778212.1 CDS O3K_07520 NC_018658.1 1562283 1565876 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; hybrid sensory histidine kinase in two-component regulatory system with EvgA complement(1562283..1565876) Escherichia coli O104:H4 str. 2011C-3493 13702965 YP_006778213.1 CDS O3K_07525 NC_018658.1 1565881 1566495 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator EvgA complement(1565881..1566495) Escherichia coli O104:H4 str. 2011C-3493 13702966 YP_006778214.1 CDS O3K_07530 NC_018658.1 1566911 1568074 D COG1566 Multidrug resistance efflux pump; EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component 1566911..1568074 Escherichia coli O104:H4 str. 2011C-3493 13702967 YP_006778215.1 CDS O3K_07535 NC_018658.1 1568074 1569612 D COG0477 Permeases of the major facilitator superfamily; putative multidrug efflux system protein Y 1568074..1569612 Escherichia coli O104:H4 str. 2011C-3493 13702968 YP_006778216.1 CDS O3K_07540 NC_018658.1 1569720 1571048 R COG3048 D-serine dehydratase; D-serine dehydratase complement(1569720..1571048) Escherichia coli O104:H4 str. 2011C-3493 13702969 YP_006778217.1 CDS O3K_07545 NC_018658.1 1571066 1571284 R COG2610 H+/gluconate symporter and related permeases; permease DsdX complement(1571066..1571284) Escherichia coli O104:H4 str. 2011C-3493 13702970 YP_006778218.1 CDS O3K_07550 NC_018658.1 1571515 1572510 D COG1609 Transcriptional regulators; sucrose operon repressor 1571515..1572510 Escherichia coli O104:H4 str. 2011C-3493 13702971 YP_006778219.1 CDS O3K_07555 NC_018658.1 1572518 1573951 R COG1621 Beta-fructosidases (levanase/invertase); sucrose-6-phosphate hydrolase complement(1572518..1573951) Escherichia coli O104:H4 str. 2011C-3493 13702972 YP_006778220.1 CDS O3K_07560 NC_018658.1 1574167 1575081 D COG0524 Sugar kinases, ribokinase family; aminoimidazole riboside kinase 1574167..1575081 Escherichia coli O104:H4 str. 2011C-3493 13702973 YP_006778221.1 CDS lacY NC_018658.1 1575153 1576400 D COG0477 Permeases of the major facilitator superfamily; galactoside permease 1575153..1576400 Escherichia coli O104:H4 str. 2011C-3493 13702974 YP_006778222.1 CDS O3K_07570 NC_018658.1 1576930 1577130 R hypothetical protein complement(1576930..1577130) Escherichia coli O104:H4 str. 2011C-3493 13702975 YP_006778223.1 CDS O3K_07575 NC_018658.1 1577262 1577441 R hypothetical protein complement(1577262..1577441) Escherichia coli O104:H4 str. 2011C-3493 13702976 YP_006778224.1 CDS O3K_07585 NC_018658.1 1578164 1578373 R prophage protein complement(1578164..1578373) Escherichia coli O104:H4 str. 2011C-3493 13702977 YP_006778225.1 CDS O3K_07590 NC_018658.1 1578736 1579407 R COG0529 Adenylylsulfate kinase and related kinases; hypothetical protein complement(1578736..1579407) Escherichia coli O104:H4 str. 2011C-3493 13702978 YP_006778226.1 CDS O3K_07595 NC_018658.1 1579404 1579571 R hypothetical protein complement(1579404..1579571) Escherichia coli O104:H4 str. 2011C-3493 13702979 YP_006778227.1 CDS O3K_07600 NC_018658.1 1579568 1579858 R hypothetical protein complement(1579568..1579858) Escherichia coli O104:H4 str. 2011C-3493 13702980 YP_006778228.1 CDS O3K_07605 NC_018658.1 1579869 1580165 R Anti-RecBCD protein 2 complement(1579869..1580165) Escherichia coli O104:H4 str. 2011C-3493 13702981 YP_006778229.1 CDS O3K_07610 NC_018658.1 1580189 1580572 R hypothetical protein complement(1580189..1580572) Escherichia coli O104:H4 str. 2011C-3493 13702982 YP_006778230.1 CDS O3K_07615 NC_018658.1 1580572 1581177 R DNA single-strand annealing protein, essential recombination function protein Erf complement(1580572..1581177) Escherichia coli O104:H4 str. 2011C-3493 13702983 YP_006778231.1 CDS O3K_07620 NC_018658.1 1581188 1581358 R hypothetical protein complement(1581188..1581358) Escherichia coli O104:H4 str. 2011C-3493 13702984 YP_006778232.1 CDS O3K_07625 NC_018658.1 1581267 1581437 R hypothetical protein complement(1581267..1581437) Escherichia coli O104:H4 str. 2011C-3493 13702985 YP_006778233.1 CDS O3K_07630 NC_018658.1 1581434 1581586 R host killing protein complement(1581434..1581586) Escherichia coli O104:H4 str. 2011C-3493 13702986 YP_006778234.1 CDS O3K_07635 NC_018658.1 1581571 1581702 R regulatory protein CIII complement(1581571..1581702) Escherichia coli O104:H4 str. 2011C-3493 13702987 YP_006778235.1 CDS O3K_07640 NC_018658.1 1581932 1582207 D COG3677 Transposase and inactivated derivatives; InsA 1581932..1582207 Escherichia coli O104:H4 str. 2011C-3493 13702988 YP_006778236.1 CDS O3K_07645 NC_018658.1 1582126 1582629 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 1582126..1582629 Escherichia coli O104:H4 str. 2011C-3493 13702989 YP_006778237.1 CDS O3K_07650 NC_018658.1 1582749 1582991 D hypothetical protein 1582749..1582991 Escherichia coli O104:H4 str. 2011C-3493 13702990 YP_006778238.1 CDS O3K_07655 NC_018658.1 1582994 1583434 D hypothetical protein 1582994..1583434 Escherichia coli O104:H4 str. 2011C-3493 13702991 YP_006778239.1 CDS O3K_07660 NC_018658.1 1583431 1584843 D COG1783 Phage terminase large subunit; terminase large subunit 1583431..1584843 Escherichia coli O104:H4 str. 2011C-3493 13702992 YP_006778240.1 CDS O3K_07665 NC_018658.1 1584882 1586972 D portal protein p19 1584882..1586972 Escherichia coli O104:H4 str. 2011C-3493 13702993 YP_006778241.1 CDS O3K_07670 NC_018658.1 1586986 1587870 D scaffold protein 1586986..1587870 Escherichia coli O104:H4 str. 2011C-3493 13702994 YP_006778242.1 CDS O3K_07675 NC_018658.1 1587882 1589153 D Major head protein (p24) (Major coat protein) 1587882..1589153 Escherichia coli O104:H4 str. 2011C-3493 13702995 YP_006778243.1 CDS O3K_07680 NC_018658.1 1589196 1589381 D phage protein 1589196..1589381 Escherichia coli O104:H4 str. 2011C-3493 13702996 YP_006778244.1 CDS O3K_07685 NC_018658.1 1589356 1589838 D packaged DNA stabilization protein p27 1589356..1589838 Escherichia coli O104:H4 str. 2011C-3493 13702997 YP_006778245.1 CDS O3K_07690 NC_018658.1 1589847 1591265 D Packaged DNA stabilization protein from phage 1589847..1591265 Escherichia coli O104:H4 str. 2011C-3493 13702998 YP_006778246.1 CDS O3K_07695 NC_018658.1 1591265 1592113 D head DNA stabilization protein 1591265..1592113 Escherichia coli O104:H4 str. 2011C-3493 13702999 YP_006778247.1 CDS O3K_07700 NC_018658.1 1592113 1592568 D Head assembly protein 1592113..1592568 Escherichia coli O104:H4 str. 2011C-3493 13703000 YP_006778248.1 CDS O3K_07705 NC_018658.1 1592571 1593263 D putative DNA transfer protein 1592571..1593263 Escherichia coli O104:H4 str. 2011C-3493 13703001 YP_006778249.1 CDS O3K_07710 NC_018658.1 1593273 1594739 D APSE-2 prophage, transfer protein gp20 1593273..1594739 Escherichia coli O104:H4 str. 2011C-3493 13703002 YP_006778250.1 CDS O3K_07715 NC_018658.1 1594739 1596583 D DNA injection protein 1594739..1596583 Escherichia coli O104:H4 str. 2011C-3493 13703003 YP_006778251.1 CDS O3K_07720 NC_018658.1 1596598 1597083 R lipoprotein complement(1596598..1597083) Escherichia coli O104:H4 str. 2011C-3493 13703004 YP_006778252.1 CDS O3K_07725 NC_018658.1 1597109 1597423 R hypothetical protein complement(1597109..1597423) Escherichia coli O104:H4 str. 2011C-3493 13703005 YP_006778253.1 CDS O3K_07730 NC_018658.1 1597420 1597671 R hypothetical protein complement(1597420..1597671) Escherichia coli O104:H4 str. 2011C-3493 13703006 YP_006778254.1 CDS O3K_07735 NC_018658.1 1597777 1597917 D hypothetical protein 1597777..1597917 Escherichia coli O104:H4 str. 2011C-3493 13703007 YP_006778255.1 CDS O3K_07740 NC_018658.1 1598150 1599028 D COG3617 Prophage antirepressor; antirepressor protein encoded by prophage CP-933N 1598150..1599028 Escherichia coli O104:H4 str. 2011C-3493 13703008 YP_006778256.1 CDS O3K_07745 NC_018658.1 1599129 1601108 D hypothetical protein 1599129..1601108 Escherichia coli O104:H4 str. 2011C-3493 13703009 YP_006778257.1 CDS O3K_07750 NC_018658.1 1601179 1603089 R COG1835 Predicted acyltransferases; hypothetical protein complement(1601179..1603089) Escherichia coli O104:H4 str. 2011C-3493 13703010 YP_006778258.1 CDS O3K_07755 NC_018658.1 1603318 1604475 R COG0582 Integrase; prophage CPS-53 integrase, CPS-53 (KpLE1) prophage complement(1603318..1604475) Escherichia coli O104:H4 str. 2011C-3493 13703011 YP_006778259.1 CDS O3K_07760 NC_018658.1 1604787 1605719 R COG2116 Formate/nitrite family of transporters; hypothetical protein complement(1604787..1605719) Escherichia coli O104:H4 str. 2011C-3493 13703013 YP_006778260.1 CDS O3K_07765 NC_018658.1 1606013 1606768 D COG2853 Surface lipoprotein; ABC transporter outer membrane lipoprotein 1606013..1606768 Escherichia coli O104:H4 str. 2011C-3493 13703014 YP_006778261.1 CDS O3K_07770 NC_018658.1 1606950 1608008 R hypothetical protein complement(1606950..1608008) Escherichia coli O104:H4 str. 2011C-3493 13703015 YP_006778262.1 CDS O3K_07775 NC_018658.1 1608374 1609714 R COG2067 Long-chain fatty acid transport protein; long-chain fatty acid outer membrane transporter complement(1608374..1609714) Escherichia coli O104:H4 str. 2011C-3493 13703016 YP_006778263.1 CDS O3K_07780 NC_018658.1 1610086 1610370 D COG3691 Uncharacterized protein conserved in bacteria; hypothetical protein 1610086..1610370 Escherichia coli O104:H4 str. 2011C-3493 13703017 YP_006778264.1 CDS fadI NC_018658.1 1610550 1611860 D COG0183 Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase 1610550..1611860 Escherichia coli O104:H4 str. 2011C-3493 13703018 YP_006778265.1 CDS fadJ NC_018658.1 1611860 1614004 D COG1024 Enoyl-CoA hydratase/carnithine racemase; multifunctional fatty acid oxidation complex subunit alpha 1611860..1614004 Escherichia coli O104:H4 str. 2011C-3493 13703019 YP_006778266.1 CDS O3K_07795 NC_018658.1 1614207 1614692 D COG2062 Phosphohistidine phosphatase SixA; phosphohistidine phosphatase 1614207..1614692 Escherichia coli O104:H4 str. 2011C-3493 13703020 YP_006778267.1 CDS O3K_07800 NC_018658.1 1615367 1615930 D putative fimbrial-like protein 1615367..1615930 Escherichia coli O104:H4 str. 2011C-3493 13703021 YP_006778268.1 CDS O3K_07805 NC_018658.1 1616012 1618654 D COG3188 P pilus assembly protein, porin PapC; putative fimbrial outer membrane usher protein StfC 1616012..1618654 Escherichia coli O104:H4 str. 2011C-3493 13703022 YP_006778269.1 CDS O3K_07810 NC_018658.1 1618674 1619426 D COG3121 P pilus assembly protein, chaperone PapD; chaperone 1618674..1619426 Escherichia coli O104:H4 str. 2011C-3493 13703023 YP_006778270.1 CDS O3K_07815 NC_018658.1 1619443 1619949 D minor fimbrial subunit 1619443..1619949 Escherichia coli O104:H4 str. 2011C-3493 13703024 YP_006778271.1 CDS O3K_07820 NC_018658.1 1619946 1620416 D fimbrial subunit protein 1619946..1620416 Escherichia coli O104:H4 str. 2011C-3493 13703025 YP_006778272.1 CDS O3K_07825 NC_018658.1 1620413 1620937 D COG3539 P pilus assembly protein, pilin FimA; fimbrial subunit protein 1620413..1620937 Escherichia coli O104:H4 str. 2011C-3493 13703026 YP_006778273.1 CDS O3K_07830 NC_018658.1 1621518 1621796 D hypothetical protein 1621518..1621796 Escherichia coli O104:H4 str. 2011C-3493 13703027 YP_006778274.1 CDS O3K_07835 NC_018658.1 1622023 1623003 D COG3547 Transposase and inactivated derivatives; IS621 transposase 1622023..1623003 Escherichia coli O104:H4 str. 2011C-3493 13703028 YP_006778275.1 CDS O3K_07840 NC_018658.1 1623197 1623748 R COG2840 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1623197..1623748) Escherichia coli O104:H4 str. 2011C-3493 13703029 YP_006778276.1 CDS O3K_07845 NC_018658.1 1623914 1624846 D COG2890 Methylase of polypeptide chain release factors; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1623914..1624846 Escherichia coli O104:H4 str. 2011C-3493 13703030 YP_006778277.1 CDS O3K_07850 NC_018658.1 1624881 1625966 D COG0082 Chorismate synthase; chorismate synthase 1624881..1625966 Escherichia coli O104:H4 str. 2011C-3493 13703031 YP_006778278.1 CDS mepA NC_018658.1 1625970 1626794 D COG3770 Murein endopeptidase; penicillin-insensitive murein endopeptidase 1625970..1626794 Escherichia coli O104:H4 str. 2011C-3493 13703032 YP_006778279.1 CDS O3K_07860 NC_018658.1 1626794 1627603 D COG0730 Predicted permeases; hypothetical protein 1626794..1627603 Escherichia coli O104:H4 str. 2011C-3493 13703033 YP_006778280.1 CDS O3K_07865 NC_018658.1 1627603 1628151 D COG3101 Uncharacterized protein conserved in bacteria; hypothetical protein 1627603..1628151 Escherichia coli O104:H4 str. 2011C-3493 13703034 YP_006778281.1 CDS O3K_07870 NC_018658.1 1628185 1628463 D hypothetical protein 1628185..1628463 Escherichia coli O104:H4 str. 2011C-3493 13703035 YP_006778282.1 CDS mnmC NC_018658.1 1628584 1630590 R COG4121 Uncharacterized conserved protein; bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase complement(1628584..1630590) Escherichia coli O104:H4 str. 2011C-3493 13703036 YP_006778283.1 CDS O3K_07880 NC_018658.1 1630749 1631969 D COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-ACP synthase 1630749..1631969 Escherichia coli O104:H4 str. 2011C-3493 13703037 YP_006778284.1 CDS O3K_07885 NC_018658.1 1632253 1633431 D COG0477 Permeases of the major facilitator superfamily; transporter 1632253..1633431 Escherichia coli O104:H4 str. 2011C-3493 13703038 YP_006778285.1 CDS flk NC_018658.1 1633428 1634423 R flagella biosynthesis regulator complement(1633428..1634423) Escherichia coli O104:H4 str. 2011C-3493 13703039 YP_006778286.1 CDS O3K_07895 NC_018658.1 1634522 1635658 D COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; erythronate-4-phosphate dehydrogenase PdxB 1634522..1635658 Escherichia coli O104:H4 str. 2011C-3493 13703040 YP_006778287.1 CDS O3K_07900 NC_018658.1 1635724 1636737 D COG0136 Aspartate-semialdehyde dehydrogenase; putative semialdehyde dehydrogenase 1635724..1636737 Escherichia coli O104:H4 str. 2011C-3493 13703041 YP_006778288.1 CDS truA NC_018658.1 1636737 1637549 D COG0101 Pseudouridylate synthase; tRNA pseudouridine synthase A 1636737..1637549 Escherichia coli O104:H4 str. 2011C-3493 13703042 YP_006778289.1 CDS O3K_07910 NC_018658.1 1637632 1638291 D COG0586 Uncharacterized membrane-associated protein; hypothetical protein 1637632..1638291 Escherichia coli O104:H4 str. 2011C-3493 13703043 YP_006778290.1 CDS O3K_07915 NC_018658.1 1638447 1639361 D COG0777 Acetyl-CoA carboxylase beta subunit; acetyl-CoA carboxylase subunit beta 1638447..1639361 Escherichia coli O104:H4 str. 2011C-3493 13703044 YP_006778291.1 CDS O3K_07920 NC_018658.1 1639431 1640699 D COG0285 Folylpolyglutamate synthase; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 1639431..1640699 Escherichia coli O104:H4 str. 2011C-3493 13703045 YP_006778292.1 CDS O3K_07925 NC_018658.1 1640689 1641351 D COG3147 Uncharacterized protein conserved in bacteria; cell division protein DedD 1640689..1641351 Escherichia coli O104:H4 str. 2011C-3493 13703046 YP_006778293.1 CDS O3K_07930 NC_018658.1 1641610 1642098 D COG1286 Uncharacterized membrane protein, required for colicin V production; colicin V production protein 1641610..1642098 Escherichia coli O104:H4 str. 2011C-3493 13703047 YP_006778294.1 CDS O3K_07935 NC_018658.1 1642135 1643652 D COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; amidophosphoribosyltransferase 1642135..1643652 Escherichia coli O104:H4 str. 2011C-3493 13703048 YP_006778295.1 CDS O3K_07940 NC_018658.1 1643747 1644316 D COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1643747..1644316 Escherichia coli O104:H4 str. 2011C-3493 13703049 YP_006778296.1 CDS O3K_07945 NC_018658.1 1644582 1645364 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; lysine/arginine/ornithine ABC transporter substrate-binding protein 1644582..1645364 Escherichia coli O104:H4 str. 2011C-3493 13703050 YP_006778297.1 CDS O3K_07950 NC_018658.1 1645585 1646367 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; histidine ABC transporter substrate-binding protein HisJ 1645585..1646367 Escherichia coli O104:H4 str. 2011C-3493 13703051 YP_006778298.1 CDS O3K_07955 NC_018658.1 1646457 1647143 D COG4215 ABC-type arginine transport system, permease component; histidine/lysine/arginine/ornithine ABC transporter permease HisQ 1646457..1647143 Escherichia coli O104:H4 str. 2011C-3493 13703052 YP_006778299.1 CDS O3K_07960 NC_018658.1 1647140 1647856 D COG4160 ABC-type arginine/histidine transport system, permease component; histidine/lysine/arginine/ornithine ABC transporter permease HisM 1647140..1647856 Escherichia coli O104:H4 str. 2011C-3493 13703053 YP_006778300.1 CDS O3K_07965 NC_018658.1 1647864 1648637 D COG4598 ABC-type histidine transport system, ATPase component; histidine/lysine/arginine/ornithine transporter subunit 1647864..1648637 Escherichia coli O104:H4 str. 2011C-3493 13703054 YP_006778301.1 CDS O3K_07970 NC_018658.1 1648834 1649736 D transposase 1648834..1649736 Escherichia coli O104:H4 str. 2011C-3493 13703055 YP_006778302.1 CDS O3K_07975 NC_018658.1 1649784 1650677 R hypothetical protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase; NAD dependent epimerase/dehydratase family protein complement(1649784..1650677) Escherichia coli O104:H4 str. 2011C-3493 13703056 YP_006778303.1 CDS folX NC_018658.1 1650698 1651060 R COG1539 Dihydroneopterin aldolase; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase complement(1650698..1651060) Escherichia coli O104:H4 str. 2011C-3493 13703057 YP_006778304.1 CDS O3K_07985 NC_018658.1 1651117 1651764 R COG0625 Glutathione S-transferase; GSH-dependent disulfide bond oxidoreductase complement(1651117..1651764) Escherichia coli O104:H4 str. 2011C-3493 13703058 YP_006778305.1 CDS O3K_07990 NC_018658.1 1651900 1652544 D COG0625 Glutathione S-transferase; glutathione S-transferase 1651900..1652544 Escherichia coli O104:H4 str. 2011C-3493 13703059 YP_006778306.1 CDS O3K_07995 NC_018658.1 1652600 1653151 D COG0622 Predicted phosphoesterase; phosphodiesterase 1652600..1653151 Escherichia coli O104:H4 str. 2011C-3493 13703060 YP_006778307.1 CDS O3K_08000 NC_018658.1 1653209 1653751 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase YfcD 1653209..1653751 Escherichia coli O104:H4 str. 2011C-3493 13703061 YP_006778308.1 CDS O3K_08005 NC_018658.1 1653784 1655304 R COG1288 Predicted membrane protein; hypothetical protein complement(1653784..1655304) Escherichia coli O104:H4 str. 2011C-3493 13703062 YP_006778309.1 CDS O3K_08010 NC_018658.1 1655494 1657638 R COG0857 BioD-like N-terminal domain of phosphotransacetylase; phosphate acetyltransferase complement(1655494..1657638) Escherichia coli O104:H4 str. 2011C-3493 13703063 YP_006778310.1 CDS O3K_08015 NC_018658.1 1657713 1658915 R COG0282 Acetate kinase; acetate kinase A/propionate kinase 2 complement(1657713..1658915) Escherichia coli O104:H4 str. 2011C-3493 13703064 YP_006778311.1 CDS O3K_08020 NC_018658.1 1659053 1659184 D hypothetical protein 1659053..1659184 Escherichia coli O104:H4 str. 2011C-3493 13703065 YP_006778312.1 CDS O3K_08025 NC_018658.1 1659253 1659708 D COG3092 Uncharacterized protein conserved in bacteria; hypothetical protein 1659253..1659708 Escherichia coli O104:H4 str. 2011C-3493 13703066 YP_006778313.1 CDS O3K_08030 NC_018658.1 1659791 1660285 D COG3013 Uncharacterized conserved protein; hypothetical protein 1659791..1660285 Escherichia coli O104:H4 str. 2011C-3493 13703067 YP_006778314.1 CDS O3K_08035 NC_018658.1 1660296 1660946 D COG0637 Predicted phosphatase/phosphohexomutase; putative phosphatase 1660296..1660946 Escherichia coli O104:H4 str. 2011C-3493 13703068 YP_006778315.1 CDS O3K_08040 NC_018658.1 1661033 1662865 D COG0471 Di- and tricarboxylate transporters; transporter 1661033..1662865 Escherichia coli O104:H4 str. 2011C-3493 13703069 YP_006778316.1 CDS O3K_08045 NC_018658.1 1662924 1663523 R COG1896 Predicted hydrolases of HD superfamily; 5'-nucleotidase complement(1662924..1663523) Escherichia coli O104:H4 str. 2011C-3493 13703070 YP_006778317.1 CDS O3K_08050 NC_018658.1 1663607 1664824 R COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase AlaT complement(1663607..1664824) Escherichia coli O104:H4 str. 2011C-3493 13703071 YP_006778318.1 CDS O3K_08055 NC_018658.1 1665744 1666682 D COG0583 Transcriptional regulator; DNA-binding transcriptional repressor LrhA 1665744..1666682 Escherichia coli O104:H4 str. 2011C-3493 13703072 YP_006778319.1 CDS O3K_08060 NC_018658.1 1667313 1667756 D COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); NADH:ubiquinone oxidoreductase subunit A 1667313..1667756 Escherichia coli O104:H4 str. 2011C-3493 13703073 YP_006778320.1 CDS O3K_08065 NC_018658.1 1667772 1668434 D COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; NADH dehydrogenase subunit B 1667772..1668434 Escherichia coli O104:H4 str. 2011C-3493 13703074 YP_006778321.1 CDS O3K_08070 NC_018658.1 1668528 1670330 D COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; NADH:ubiquinone oxidoreductase subunit C/D 1668528..1670330 Escherichia coli O104:H4 str. 2011C-3493 13703075 YP_006778322.1 CDS O3K_08075 NC_018658.1 1670333 1670833 D COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; NADH dehydrogenase subunit E 1670333..1670833 Escherichia coli O104:H4 str. 2011C-3493 13703076 YP_006778323.1 CDS O3K_08080 NC_018658.1 1670830 1672167 D COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; NADH dehydrogenase I subunit F 1670830..1672167 Escherichia coli O104:H4 str. 2011C-3493 13703077 YP_006778324.1 CDS O3K_08085 NC_018658.1 1672220 1674946 D COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); NADH dehydrogenase subunit G 1672220..1674946 Escherichia coli O104:H4 str. 2011C-3493 13703078 YP_006778325.1 CDS O3K_08090 NC_018658.1 1674943 1675920 D COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); NADH:ubiquinone oxidoreductase subunit H 1674943..1675920 Escherichia coli O104:H4 str. 2011C-3493 13703079 YP_006778326.1 CDS O3K_08095 NC_018658.1 1675935 1676477 D COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); NADH dehydrogenase subunit I 1675935..1676477 Escherichia coli O104:H4 str. 2011C-3493 13703080 YP_006778327.1 CDS O3K_08100 NC_018658.1 1676489 1677043 D COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); NADH:ubiquinone oxidoreductase subunit J 1676489..1677043 Escherichia coli O104:H4 str. 2011C-3493 13703081 YP_006778328.1 CDS O3K_08105 NC_018658.1 1677040 1677342 D COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); NADH:ubiquinone oxidoreductase subunit K 1677040..1677342 Escherichia coli O104:H4 str. 2011C-3493 13703082 YP_006778329.1 CDS O3K_08110 NC_018658.1 1677339 1679180 D COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; NADH:ubiquinone oxidoreductase subunit L 1677339..1679180 Escherichia coli O104:H4 str. 2011C-3493 13703083 YP_006778330.1 CDS O3K_08115 NC_018658.1 1679344 1680873 D COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); NADH:ubiquinone oxidoreductase subunit M 1679344..1680873 Escherichia coli O104:H4 str. 2011C-3493 13703084 YP_006778331.1 CDS O3K_08120 NC_018658.1 1680880 1682337 D COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); NADH:ubiquinone oxidoreductase subunit N 1680880..1682337 Escherichia coli O104:H4 str. 2011C-3493 13703085 YP_006778332.1 CDS O3K_08125 NC_018658.1 1682404 1682907 R hypothetical protein complement(1682404..1682907) Escherichia coli O104:H4 str. 2011C-3493 13703086 YP_006778333.1 CDS O3K_08130 NC_018658.1 1683033 1683212 R COG2234 Predicted aminopeptidases; Zn-dependent exopeptidase complement(1683033..1683212) Escherichia coli O104:H4 str. 2011C-3493 13703087 YP_006778334.1 CDS O3K_08145 NC_018658.1 1685437 1686354 R COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; ribonuclease Z complement(1685437..1686354) Escherichia coli O104:H4 str. 2011C-3493 13703088 YP_006778335.1 CDS O3K_08150 NC_018658.1 1686419 1686880 D COG2153 Predicted acyltransferase; putative acyltransferase 1686419..1686880 Escherichia coli O104:H4 str. 2011C-3493 13703089 YP_006778336.1 CDS O3K_08155 NC_018658.1 1686935 1687240 D COG4575 Uncharacterized conserved protein; hypothetical protein 1686935..1687240 Escherichia coli O104:H4 str. 2011C-3493 13703090 YP_006778337.1 CDS O3K_08160 NC_018658.1 1687319 1688614 D COG1169 Isochorismate synthase; menaquinone-specific isochorismate synthase 1687319..1688614 Escherichia coli O104:H4 str. 2011C-3493 13703091 YP_006778338.1 CDS O3K_08165 NC_018658.1 1688703 1690373 D COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1688703..1690373 Escherichia coli O104:H4 str. 2011C-3493 13703092 YP_006778339.1 CDS O3K_08170 NC_018658.1 1690370 1691128 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase 1690370..1691128 Escherichia coli O104:H4 str. 2011C-3493 13703093 YP_006778340.1 CDS O3K_08175 NC_018658.1 1691143 1692000 D COG0447 Dihydroxynaphthoic acid synthase; dihydroxynaphthoic acid synthetase 1691143..1692000 Escherichia coli O104:H4 str. 2011C-3493 13703094 YP_006778341.1 CDS O3K_08180 NC_018658.1 1692000 1692962 D COG1441 O-succinylbenzoate synthase; O-succinylbenzoate synthase 1692000..1692962 Escherichia coli O104:H4 str. 2011C-3493 13703095 YP_006778342.1 CDS O3K_08185 NC_018658.1 1692959 1694314 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; O-succinylbenzoic acid--CoA ligase 1692959..1694314 Escherichia coli O104:H4 str. 2011C-3493 13703096 YP_006778343.1 CDS O3K_08190 NC_018658.1 1694424 1694690 D COG1601 Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain; signal transduction protein PmrD 1694424..1694690 Escherichia coli O104:H4 str. 2011C-3493 13703097 YP_006778344.1 CDS O3K_08195 NC_018658.1 1694684 1695070 R 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF complement(1694684..1695070) Escherichia coli O104:H4 str. 2011C-3493 13703098 YP_006778345.1 CDS O3K_08200 NC_018658.1 1695070 1695405 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE complement(1695070..1695405) Escherichia coli O104:H4 str. 2011C-3493 13703099 YP_006778346.1 CDS arnT NC_018658.1 1695402 1697054 R COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family; 4-amino-4-deoxy-L-arabinose transferase complement(1695402..1697054) Escherichia coli O104:H4 str. 2011C-3493 13703100 YP_006778347.1 CDS O3K_08210 NC_018658.1 1697054 1697944 R COG0726 Predicted xylanase/chitin deacetylase; 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase ArnD complement(1697054..1697944) Escherichia coli O104:H4 str. 2011C-3493 13703101 YP_006778348.1 CDS O3K_08215 NC_018658.1 1697941 1699923 R COG0223 Methionyl-tRNA formyltransferase; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase complement(1697941..1699923) Escherichia coli O104:H4 str. 2011C-3493 13703102 YP_006778349.1 CDS O3K_08220 NC_018658.1 1699923 1700891 R COG0463 Glycosyltransferases involved in cell wall biogenesis; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase complement(1699923..1700891) Escherichia coli O104:H4 str. 2011C-3493 13703103 YP_006778350.1 CDS O3K_08225 NC_018658.1 1700895 1702034 R COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase complement(1700895..1702034) Escherichia coli O104:H4 str. 2011C-3493 13703104 YP_006778351.1 CDS O3K_08230 NC_018658.1 1702342 1702944 D lipopolysaccharide core heptose(II)-phosphate phosphatase 1702342..1702944 Escherichia coli O104:H4 str. 2011C-3493 13703105 YP_006778352.1 CDS O3K_08235 NC_018658.1 1702983 1703408 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; nucleoside triphosphatase NudI complement(1702983..1703408) Escherichia coli O104:H4 str. 2011C-3493 13703106 YP_006778353.1 CDS O3K_08240 NC_018658.1 1703687 1704229 D putative outer membrane porin protein 1703687..1704229 Escherichia coli O104:H4 str. 2011C-3493 13703107 YP_006778354.1 CDS O3K_08245 NC_018658.1 1704329 1705531 D COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; hypothetical protein 1704329..1705531 Escherichia coli O104:H4 str. 2011C-3493 13703108 YP_006778355.1 CDS O3K_08250 NC_018658.1 1705667 1706056 D COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; 2-keto-3-deoxy-L-rhamnonate aldolase 1705667..1706056 Escherichia coli O104:H4 str. 2011C-3493 13703109 YP_006778356.1 CDS O3K_08255 NC_018658.1 1706097 1706999 R COG5464 Uncharacterized conserved protein; hypothetical protein complement(1706097..1706999) Escherichia coli O104:H4 str. 2011C-3493 13703110 YP_006778357.1 CDS glpC NC_018658.1 1707193 1708383 R COG0247 Fe-S oxidoreductase; sn-glycerol-3-phosphate dehydrogenase subunit C complement(1707193..1708383) Escherichia coli O104:H4 str. 2011C-3493 13703111 YP_006778358.1 CDS O3K_08265 NC_018658.1 1708380 1709639 R COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(1708380..1709639) Escherichia coli O104:H4 str. 2011C-3493 13703112 YP_006778359.1 CDS glpA NC_018658.1 1709629 1711257 R COG0578 Glycerol-3-phosphate dehydrogenase; sn-glycerol-3-phosphate dehydrogenase subunit A complement(1709629..1711257) Escherichia coli O104:H4 str. 2011C-3493 13703113 YP_006778360.1 CDS glpT NC_018658.1 1711530 1712888 D COG2271 Sugar phosphate permease; sn-glycerol-3-phosphate transporter 1711530..1712888 Escherichia coli O104:H4 str. 2011C-3493 13703114 YP_006778361.1 CDS glpQ NC_018658.1 1712893 1713969 D COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphodiester phosphodiesterase 1712893..1713969 Escherichia coli O104:H4 str. 2011C-3493 13703115 YP_006778362.1 CDS O3K_08285 NC_018658.1 1714011 1714217 R hypothetical protein complement(1714011..1714217) Escherichia coli O104:H4 str. 2011C-3493 13703116 YP_006778363.1 CDS O3K_08290 NC_018658.1 1714398 1715378 D COG3039 Transposase and inactivated derivatives, IS5 family; IS5 transposase and trans-activator 1714398..1715378 Escherichia coli O104:H4 str. 2011C-3493 13703117 YP_006778364.1 CDS O3K_08295 NC_018658.1 1715632 1716282 D hypothetical protein 1715632..1716282 Escherichia coli O104:H4 str. 2011C-3493 13703118 YP_006778365.1 CDS O3K_08300 NC_018658.1 1716336 1716590 R COG0633 Ferredoxin; 2Fe-2S ferredoxin complement(1716336..1716590) Escherichia coli O104:H4 str. 2011C-3493 13703119 YP_006778366.1 CDS nrdB NC_018658.1 1716590 1717720 R COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta complement(1716590..1717720) Escherichia coli O104:H4 str. 2011C-3493 13703120 YP_006778367.1 CDS O3K_08310 NC_018658.1 1717809 1720094 R COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha complement(1717809..1720094) Escherichia coli O104:H4 str. 2011C-3493 13703121 YP_006778368.1 CDS O3K_08315 NC_018658.1 1720790 1724524 D COG3468 Type V secretory pathway, adhesin AidA; adhesin 1720790..1724524 Escherichia coli O104:H4 str. 2011C-3493 13703122 YP_006778369.1 CDS O3K_08320 NC_018658.1 1724652 1725374 R COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase; bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase complement(1724652..1725374) Escherichia coli O104:H4 str. 2011C-3493 13703123 YP_006778370.1 CDS O3K_08325 NC_018658.1 1725521 1728148 D COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA gyrase subunit A 1725521..1728148 Escherichia coli O104:H4 str. 2011C-3493 13703124 YP_006778371.1 CDS O3K_08330 NC_018658.1 1728297 1729985 D COG4685 Uncharacterized protein conserved in bacteria; hypothetical protein 1728297..1729985 Escherichia coli O104:H4 str. 2011C-3493 13703125 YP_006778372.1 CDS O3K_08335 NC_018658.1 1729982 1730605 D COG3234 Uncharacterized protein conserved in bacteria; hypothetical protein 1729982..1730605 Escherichia coli O104:H4 str. 2011C-3493 13703126 YP_006778373.1 CDS O3K_08340 NC_018658.1 1730539 1735143 D COG2373 Large extracellular alpha-helical protein; alpha-2-macroglobulin family protein 1730539..1735143 Escherichia coli O104:H4 str. 2011C-3493 13703127 YP_006778374.1 CDS O3K_08345 NC_018658.1 1735144 1736793 D COG5445 Predicted secreted protein; hypothetical protein 1735144..1736793 Escherichia coli O104:H4 str. 2011C-3493 13703128 YP_006778375.1 CDS O3K_08350 NC_018658.1 1736798 1737574 D COG4676 Uncharacterized protein conserved in bacteria; hypothetical protein 1736798..1737574 Escherichia coli O104:H4 str. 2011C-3493 13703129 YP_006778376.1 CDS O3K_08355 NC_018658.1 1737849 1740698 D COG0642 Signal transduction histidine kinase; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 1737849..1740698 Escherichia coli O104:H4 str. 2011C-3493 13703130 YP_006778377.1 CDS O3K_08360 NC_018658.1 1740898 1741548 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator RcsB complement(1740898..1741548) Escherichia coli O104:H4 str. 2011C-3493 13703131 YP_006778378.1 CDS O3K_08365 NC_018658.1 1741565 1744237 R COG0642 Signal transduction histidine kinase; phosphotransfer intermediate protein in two-component regulatory system with RcsBC complement(1741565..1744237) Escherichia coli O104:H4 str. 2011C-3493 13703132 YP_006778379.1 CDS O3K_08370 NC_018658.1 1744976 1746079 D COG3203 Outer membrane protein (porin); outer membrane porin protein C 1744976..1746079 Escherichia coli O104:H4 str. 2011C-3493 13703133 YP_006778380.1 CDS O3K_08375 NC_018658.1 1746191 1747246 D COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; thiamine biosynthesis lipoprotein ApbE 1746191..1747246 Escherichia coli O104:H4 str. 2011C-3493 13703134 YP_006778381.1 CDS O3K_08380 NC_018658.1 1747320 1748384 D COG2169 Adenosine deaminase; bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase 1747320..1748384 Escherichia coli O104:H4 str. 2011C-3493 13703135 YP_006778382.1 CDS O3K_08385 NC_018658.1 1748384 1749034 D COG3145 Alkylated DNA repair protein; alpha-ketoglutarate-dependent dioxygenase AlkB 1748384..1749034 Escherichia coli O104:H4 str. 2011C-3493 13703136 YP_006778383.1 CDS O3K_08390 NC_018658.1 1749110 1750753 D COG4615 ABC-type siderophore export system, fused ATPase and permease components; multidrug transporter membrane protein/ATP-binding component 1749110..1750753 Escherichia coli O104:H4 str. 2011C-3493 13703137 YP_006778384.1 CDS O3K_08395 NC_018658.1 1750971 1752617 D COG0579 Predicted dehydrogenase; malate:quinone oxidoreductase 1750971..1752617 Escherichia coli O104:H4 str. 2011C-3493 13703138 YP_006778385.1 CDS O3K_08400 NC_018658.1 1752766 1753254 R COG4574 Serine protease inhibitor ecotin; ecotin complement(1752766..1753254) Escherichia coli O104:H4 str. 2011C-3493 13703139 YP_006778386.1 CDS O3K_08405 NC_018658.1 1753389 1753562 R COG1626 Neutral trehalase; hypothetical protein complement(1753389..1753562) Escherichia coli O104:H4 str. 2011C-3493 13703140 YP_006778387.1 CDS O3K_08410 NC_018658.1 1753662 1754156 D COG1145 Ferredoxin; ferredoxin-type protein 1753662..1754156 Escherichia coli O104:H4 str. 2011C-3493 13703141 YP_006778388.1 CDS O3K_08415 NC_018658.1 1754146 1754409 D COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase; assembly protein for periplasmic nitrate reductase 1754146..1754409 Escherichia coli O104:H4 str. 2011C-3493 13703142 YP_006778389.1 CDS O3K_08420 NC_018658.1 1754406 1756892 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; nitrate reductase catalytic subunit 1754406..1756892 Escherichia coli O104:H4 str. 2011C-3493 13703143 YP_006778390.1 CDS napG NC_018658.1 1756899 1757594 D COG1145 Ferredoxin; quinol dehydrogenase periplasmic component 1756899..1757594 Escherichia coli O104:H4 str. 2011C-3493 13703144 YP_006778391.1 CDS napH NC_018658.1 1757581 1758444 D COG0348 Polyferredoxin; quinol dehydrogenase membrane component 1757581..1758444 Escherichia coli O104:H4 str. 2011C-3493 13703145 YP_006778392.1 CDS napB NC_018658.1 1758441 1758890 D COG3043 Nitrate reductase cytochrome c-type subunit; nitrate reductase cytochrome C550 subunit 1758441..1758890 Escherichia coli O104:H4 str. 2011C-3493 13703146 YP_006778393.1 CDS O3K_08440 NC_018658.1 1758900 1759502 D COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; cytochrome c-type protein NapC 1758900..1759502 Escherichia coli O104:H4 str. 2011C-3493 13703147 YP_006778394.1 CDS O3K_08445 NC_018658.1 1759521 1760138 D COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component; cytochrome c biogenesis protein CcmA 1759521..1760138 Escherichia coli O104:H4 str. 2011C-3493 13703148 YP_006778395.1 CDS O3K_08450 NC_018658.1 1760135 1760797 D COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component; Heme exporter protein B 1760135..1760797 Escherichia coli O104:H4 str. 2011C-3493 13703149 YP_006778396.1 CDS O3K_08455 NC_018658.1 1760839 1761576 D COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; heme exporter protein C 1760839..1761576 Escherichia coli O104:H4 str. 2011C-3493 13703150 YP_006778397.1 CDS O3K_08460 NC_018658.1 1761573 1761782 D COG3114 Heme exporter protein D; cytochrome c biogenesis protein CcmD 1761573..1761782 Escherichia coli O104:H4 str. 2011C-3493 13703151 YP_006778398.1 CDS O3K_08465 NC_018658.1 1761779 1762258 D COG2332 Cytochrome c-type biogenesis protein CcmE; cytochrome c-type biogenesis protein CcmE 1761779..1762258 Escherichia coli O104:H4 str. 2011C-3493 13703152 YP_006778399.1 CDS O3K_08470 NC_018658.1 1762255 1764198 D COG1138 Cytochrome c biogenesis factor; heme lyase, CcmF subunit 1762255..1764198 Escherichia coli O104:H4 str. 2011C-3493 13703153 YP_006778400.1 CDS O3K_08475 NC_018658.1 1764195 1764752 D COG0526 Thiol-disulfide isomerase and thioredoxins; thiol:disulfide interchange protein DsbE 1764195..1764752 Escherichia coli O104:H4 str. 2011C-3493 13703154 YP_006778401.1 CDS O3K_08480 NC_018658.1 1764749 1765801 D COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; heme lyase, CcmH subunit 1764749..1765801 Escherichia coli O104:H4 str. 2011C-3493 13703155 YP_006778402.1 CDS O3K_08485 NC_018658.1 1765836 1766483 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator NarP complement(1765836..1766483) Escherichia coli O104:H4 str. 2011C-3493 13703156 YP_006778403.1 CDS O3K_08490 NC_018658.1 1766884 1769169 D COG3468 Type V secretory pathway, adhesin AidA; putative autotransporter 1766884..1769169 Escherichia coli O104:H4 str. 2011C-3493 13703157 YP_006778404.1 CDS O3K_08495 NC_018658.1 1769182 1769394 D autotransporter outer membrane protein 1769182..1769394 Escherichia coli O104:H4 str. 2011C-3493 13703158 YP_006778405.1 CDS O3K_08500 NC_018658.1 1769648 1771408 R COG3083 Predicted hydrolase of alkaline phosphatase superfamily; putative hydrolase, inner membrane complement(1769648..1771408) Escherichia coli O104:H4 str. 2011C-3493 13703160 YP_006778406.1 CDS O3K_08505 NC_018658.1 1771428 1771655 R COG3082 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1771428..1771655) Escherichia coli O104:H4 str. 2011C-3493 13703161 YP_006778407.1 CDS O3K_08510 NC_018658.1 1771837 1772844 D COG3081 Nucleoid-associated protein; nucleoid-associated protein NdpA 1771837..1772844 Escherichia coli O104:H4 str. 2011C-3493 13703162 YP_006778408.1 CDS O3K_08515 NC_018658.1 1772983 1773267 R COG1825 Ribosomal protein L25 (general stress protein Ctc); 50S ribosomal protein L25 complement(1772983..1773267) Escherichia coli O104:H4 str. 2011C-3493 13703163 YP_006778409.1 CDS O3K_08520 NC_018658.1 1773392 1775152 R COG1061 DNA or RNA helicases of superfamily II; nucleic acid ATP-dependent helicase complement(1773392..1775152) Escherichia coli O104:H4 str. 2011C-3493 13703164 YP_006778410.1 CDS O3K_08525 NC_018658.1 1775301 1775996 D COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA pseudouridylate synthase A 1775301..1775996 Escherichia coli O104:H4 str. 2011C-3493 13703165 YP_006778411.1 CDS O3K_08530 NC_018658.1 1776024 1777214 D COG0477 Permeases of the major facilitator superfamily; bicyclomycin/multidrug efflux system protein 1776024..1777214 Escherichia coli O104:H4 str. 2011C-3493 13703166 YP_006778412.1 CDS O3K_08535 NC_018658.1 1777547 1777891 D hypothetical protein 1777547..1777891 Escherichia coli O104:H4 str. 2011C-3493 13703167 YP_006778413.1 CDS O3K_08540 NC_018658.1 1777895 1779484 R COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; microcin C ABC transporter ATP-binding protein YejF complement(1777895..1779484) Escherichia coli O104:H4 str. 2011C-3493 13703168 YP_006778414.1 CDS O3K_08545 NC_018658.1 1779486 1780511 R COG4239 ABC-type uncharacterized transport system, permease component; microcin C ABC transporter permease complement(1779486..1780511) Escherichia coli O104:H4 str. 2011C-3493 13703169 YP_006778415.1 CDS O3K_08550 NC_018658.1 1780511 1781605 R COG4174 ABC-type uncharacterized transport system, permease component; microcin C ABC transporter permease YejB complement(1780511..1781605) Escherichia coli O104:H4 str. 2011C-3493 13703170 YP_006778416.1 CDS O3K_08555 NC_018658.1 1781606 1783420 R COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein complement(1781606..1783420) Escherichia coli O104:H4 str. 2011C-3493 13703171 YP_006778417.1 CDS O3K_08560 NC_018658.1 1783502 1785058 R COG2200 FOG: EAL domain; phage resistance protein complement(1783502..1785058) Escherichia coli O104:H4 str. 2011C-3493 13703172 YP_006778418.1 CDS spr NC_018658.1 1785239 1785805 R COG0791 Cell wall-associated hydrolases (invasion-associated proteins); outer membrane lipoprotein complement(1785239..1785805) Escherichia coli O104:H4 str. 2011C-3493 13703173 YP_006778419.1 CDS O3K_08570 NC_018658.1 1786217 1786930 R COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein complement(1786217..1786930) Escherichia coli O104:H4 str. 2011C-3493 13703174 YP_006778420.1 CDS O3K_08575 NC_018658.1 1786969 1787955 R COG0523 Putative GTPases (G3E family); hypothetical protein complement(1786969..1787955) Escherichia coli O104:H4 str. 2011C-3493 13703175 YP_006778421.1 CDS O3K_08580 NC_018658.1 1788073 1789539 R COG0246 Mannitol-1-phosphate/altronate dehydrogenases; sugar dehydrogenase, NAD-dependent complement(1788073..1789539) Escherichia coli O104:H4 str. 2011C-3493 13703176 YP_006778422.1 CDS O3K_08585 NC_018658.1 1789762 1790334 R COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); elongation factor P complement(1789762..1790334) Escherichia coli O104:H4 str. 2011C-3493 13703177 YP_006778423.1 CDS O3K_08590 NC_018658.1 1790489 1790743 D COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 1790489..1790743 Escherichia coli O104:H4 str. 2011C-3493 13703178 YP_006778424.1 CDS O3K_08595 NC_018658.1 1790740 1791921 R COG0477 Permeases of the major facilitator superfamily; sugar efflux transporter B complement(1790740..1791921) Escherichia coli O104:H4 str. 2011C-3493 13703179 YP_006778425.1 CDS O3K_08600 NC_018658.1 1792289 1793419 D COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; PTS system fructose-specific transporter subunit IIA/HPr protein 1792289..1793419 Escherichia coli O104:H4 str. 2011C-3493 13703180 YP_006778426.1 CDS fruK NC_018658.1 1793419 1794357 D COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); 1-phosphofructokinase 1793419..1794357 Escherichia coli O104:H4 str. 2011C-3493 13703181 YP_006778427.1 CDS O3K_08610 NC_018658.1 1794374 1796065 D COG3925 N-terminal domain of the phosphotransferase system fructose-specific component IIB; PTS system fructose-specific transporter subunit IIBC 1794374..1796065 Escherichia coli O104:H4 str. 2011C-3493 13703182 YP_006778428.1 CDS O3K_08615 NC_018658.1 1796489 1797430 D COG0524 Sugar kinases, ribokinase family; pseudouridine kinase 1796489..1797430 Escherichia coli O104:H4 str. 2011C-3493 13703183 YP_006778429.1 CDS O3K_08620 NC_018658.1 1797418 1798356 D COG2313 Uncharacterized enzyme involved in pigment biosynthesis; hypothetical protein 1797418..1798356 Escherichia coli O104:H4 str. 2011C-3493 13703184 YP_006778430.1 CDS O3K_08625 NC_018658.1 1798450 1799700 D COG1972 Nucleoside permease; sodium/proton nucleoside transporter 1798450..1799700 Escherichia coli O104:H4 str. 2011C-3493 13703185 YP_006778431.1 CDS O3K_08630 NC_018658.1 1799768 1800427 R COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; DNA-binding transcriptional activator YeiL complement(1799768..1800427) Escherichia coli O104:H4 str. 2011C-3493 13703186 YP_006778432.1 CDS rihB NC_018658.1 1800596 1801537 D COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase 2 1800596..1801537 Escherichia coli O104:H4 str. 2011C-3493 13703187 YP_006778433.1 CDS O3K_08640 NC_018658.1 1801637 1802887 D COG1972 Nucleoside permease; nucleoside transporter 1801637..1802887 Escherichia coli O104:H4 str. 2011C-3493 13703188 YP_006778434.1 CDS O3K_08645 NC_018658.1 1802943 1804031 R COG2771 DNA-binding HTH domain-containing proteins; putative kinase complement(1802943..1804031) Escherichia coli O104:H4 str. 2011C-3493 13703189 YP_006778435.1 CDS O3K_08650 NC_018658.1 1804035 1804892 R COG0648 Endonuclease IV; endonuclease IV complement(1804035..1804892) Escherichia coli O104:H4 str. 2011C-3493 13703190 YP_006778436.1 CDS O3K_08655 NC_018658.1 1804966 1806015 R COG2855 Predicted membrane protein; hypothetical protein complement(1804966..1806015) Escherichia coli O104:H4 str. 2011C-3493 13703191 YP_006778437.1 CDS O3K_08660 NC_018658.1 1806114 1806995 D COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator 1806114..1806995 Escherichia coli O104:H4 str. 2011C-3493 13703192 YP_006778438.1 CDS O3K_08665 NC_018658.1 1807200 1808669 D COG0833 Amino acid transporters; lysine transporter 1807200..1808669 Escherichia coli O104:H4 str. 2011C-3493 13703193 YP_006778439.1 CDS O3K_08670 NC_018658.1 1808962 1810953 D COG4771 Outer membrane receptor for ferrienterochelin and colicins; catecholate siderophore receptor CirA 1808962..1810953 Escherichia coli O104:H4 str. 2011C-3493 13703194 YP_006778440.1 CDS O3K_08675 NC_018658.1 1810985 1811821 R COG0627 Predicted esterase; esterase complement(1810985..1811821) Escherichia coli O104:H4 str. 2011C-3493 13703195 YP_006778441.1 CDS folE NC_018658.1 1812079 1812747 D COG0302 GTP cyclohydrolase I; GTP cyclohydrolase I 1812079..1812747 Escherichia coli O104:H4 str. 2011C-3493 13703196 YP_006778442.1 CDS O3K_08685 NC_018658.1 1812764 1813921 D COG2311 Predicted membrane protein; hypothetical protein 1812764..1813921 Escherichia coli O104:H4 str. 2011C-3493 13703197 YP_006778443.1 CDS O3K_08690 NC_018658.1 1814063 1815103 D COG1609 Transcriptional regulators; DNA-binding transcriptional regulator GalS 1814063..1815103 Escherichia coli O104:H4 str. 2011C-3493 13703198 YP_006778444.1 CDS O3K_08695 NC_018658.1 1815383 1816381 D COG1879 ABC-type sugar transport system, periplasmic component; methyl-galactoside ABC transporter substrate-binding protein MglB 1815383..1816381 Escherichia coli O104:H4 str. 2011C-3493 13703199 YP_006778445.1 CDS O3K_08700 NC_018658.1 1816442 1817962 D COG1129 ABC-type sugar transport system, ATPase component; galactose/methyl galaxtoside transporter ATP-binding protein 1816442..1817962 Escherichia coli O104:H4 str. 2011C-3493 13703200 YP_006778446.1 CDS mglC NC_018658.1 1817978 1818988 D COG4211 ABC-type glucose/galactose transport system, permease component; beta-methylgalactoside transporter inner membrane protein 1817978..1818988 Escherichia coli O104:H4 str. 2011C-3493 13703201 YP_006778447.1 CDS O3K_08710 NC_018658.1 1819059 1820294 R COG0167 Dihydroorotate dehydrogenase; dihydropyrimidine dehydrogenase subunit B complement(1819059..1820294) Escherichia coli O104:H4 str. 2011C-3493 13703202 YP_006778448.1 CDS O3K_08715 NC_018658.1 1820288 1821526 R COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; dihydropyrimidine dehydrogenase subunit A complement(1820288..1821526) Escherichia coli O104:H4 str. 2011C-3493 13703203 YP_006778449.1 CDS O3K_08720 NC_018658.1 1821845 1822084 R hypothetical protein complement(1821845..1822084) Escherichia coli O104:H4 str. 2011C-3493 13703204 YP_006778450.1 CDS O3K_08725 NC_018658.1 1822087 1822806 R COG2949 Uncharacterized membrane protein; vancomycin high temperature exclusion protein complement(1822087..1822806) Escherichia coli O104:H4 str. 2011C-3493 13703205 YP_006778451.1 CDS O3K_08730 NC_018658.1 1822956 1823840 R COG0295 Cytidine deaminase; cytidine deaminase complement(1822956..1823840) Escherichia coli O104:H4 str. 2011C-3493 13703206 YP_006778452.1 CDS O3K_08735 NC_018658.1 1823970 1824665 R COG1346 Putative effector of murein hydrolase; hypothetical protein complement(1823970..1824665) Escherichia coli O104:H4 str. 2011C-3493 13703207 YP_006778453.1 CDS O3K_08740 NC_018658.1 1824662 1825060 R COG1380 Putative effector of murein hydrolase LrgA; hypothetical protein complement(1824662..1825060) Escherichia coli O104:H4 str. 2011C-3493 13703208 YP_006778454.1 CDS O3K_08745 NC_018658.1 1825299 1826246 D COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase C 1825299..1826246 Escherichia coli O104:H4 str. 2011C-3493 13703209 YP_006778455.1 CDS O3K_08750 NC_018658.1 1826619 1826702 R hypothetical protein complement(1826619..1826702) Escherichia coli O104:H4 str. 2011C-3493 13703210 YP_006778456.1 CDS O3K_08755 NC_018658.1 1826926 1828362 D COG1538 Outer membrane protein; multidrug resistance outer membrane protein MdtQ 1826926..1828362 Escherichia coli O104:H4 str. 2011C-3493 13703211 YP_006778457.1 CDS O3K_08760 NC_018658.1 1828415 1829176 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1828415..1829176 Escherichia coli O104:H4 str. 2011C-3493 13703212 YP_006778458.1 CDS O3K_08765 NC_018658.1 1829306 1829884 R COG0586 Uncharacterized membrane-associated protein; inner membrane protein complement(1829306..1829884) Escherichia coli O104:H4 str. 2011C-3493 13703213 YP_006778459.1 CDS O3K_08770 NC_018658.1 1830054 1830641 D inner membrane protein YohC 1830054..1830641 Escherichia coli O104:H4 str. 2011C-3493 13703214 YP_006778460.1 CDS pbpG NC_018658.1 1830815 1831747 D COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine endopeptidase 1830815..1831747 Escherichia coli O104:H4 str. 2011C-3493 13703215 YP_006778461.1 CDS O3K_08780 NC_018658.1 1831785 1833500 R COG0277 FAD/FMN-containing dehydrogenases; D-lactate dehydrogenase complement(1831785..1833500) Escherichia coli O104:H4 str. 2011C-3493 13703216 YP_006778462.1 CDS O3K_08785 NC_018658.1 1833696 1835993 D COG1472 Beta-glucosidase-related glycosidases; beta-D-glucoside glucohydrolase 1833696..1835993 Escherichia coli O104:H4 str. 2011C-3493 13703217 YP_006778463.1 CDS O3K_08790 NC_018658.1 1836204 1837121 D COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); transporter subunit 1836204..1837121 Escherichia coli O104:H4 str. 2011C-3493 13703218 YP_006778464.1 CDS O3K_08795 NC_018658.1 1837128 1838285 D COG1174 ABC-type proline/glycine betaine transport systems, permease component; transporter subunit 1837128..1838285 Escherichia coli O104:H4 str. 2011C-3493 13703219 YP_006778465.1 CDS O3K_08800 NC_018658.1 1838278 1839204 D COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; ABC transporter ATP-binding protein 1838278..1839204 Escherichia coli O104:H4 str. 2011C-3493 13703220 YP_006778466.1 CDS O3K_08805 NC_018658.1 1839209 1839940 D COG1174 ABC-type proline/glycine betaine transport systems, permease component; ABC transporter quaternary amine uptake (QAT) family, permease 1839209..1839940 Escherichia coli O104:H4 str. 2011C-3493 13703221 YP_006778467.1 CDS O3K_08810 NC_018658.1 1839921 1840028 R hypothetical protein complement(1839921..1840028) Escherichia coli O104:H4 str. 2011C-3493 13703222 YP_006778468.1 CDS O3K_08815 NC_018658.1 1840088 1840819 R COG0789 Predicted transcriptional regulators; transcriptional regulator MirA complement(1840088..1840819) Escherichia coli O104:H4 str. 2011C-3493 13703223 YP_006778469.1 CDS O3K_08820 NC_018658.1 1841041 1842726 D COG3275 Putative regulator of cell autolysis; putative sensory kinase in two-component system with YehT 1841041..1842726 Escherichia coli O104:H4 str. 2011C-3493 13699293 YP_006778470.1 CDS O3K_08825 NC_018658.1 1842723 1843442 D COG3279 Response regulator of the LytR/AlgR family; putative two-component response-regulatory protein YehT 1842723..1843442 Escherichia coli O104:H4 str. 2011C-3493 13699294 YP_006778471.1 CDS O3K_08830 NC_018658.1 1843489 1843959 D COG4807 Uncharacterized protein conserved in bacteria; hypothetical protein 1843489..1843959 Escherichia coli O104:H4 str. 2011C-3493 13699295 YP_006778472.1 CDS O3K_08835 NC_018658.1 1844000 1844461 R COG4808 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1844000..1844461) Escherichia coli O104:H4 str. 2011C-3493 13699296 YP_006778473.1 CDS O3K_08840 NC_018658.1 1844586 1846586 R hypothetical protein complement(1844586..1846586) Escherichia coli O104:H4 str. 2011C-3493 13699297 YP_006778474.1 CDS O3K_08845 NC_018658.1 1846583 1847719 R hypothetical protein complement(1846583..1847719) Escherichia coli O104:H4 str. 2011C-3493 13699298 YP_006778475.1 CDS O3K_08850 NC_018658.1 1847712 1849991 R hypothetical protein complement(1847712..1849991) Escherichia coli O104:H4 str. 2011C-3493 13699299 YP_006778476.1 CDS O3K_08855 NC_018658.1 1850002 1851090 R COG0714 MoxR-like ATPases; putative transporter subunit complement(1850002..1851090) Escherichia coli O104:H4 str. 2011C-3493 13699300 YP_006778477.1 CDS O3K_08860 NC_018658.1 1852131 1852220 D hypothetical protein 1852131..1852220 Escherichia coli O104:H4 str. 2011C-3493 13699301 YP_006778478.1 CDS O3K_08865 NC_018658.1 1852708 1856340 R hypothetical protein complement(1852708..1856340) Escherichia coli O104:H4 str. 2011C-3493 13699302 YP_006778479.1 CDS O3K_08870 NC_018658.1 1856350 1860144 R COG3831 Uncharacterized conserved protein; hypothetical protein complement(1856350..1860144) Escherichia coli O104:H4 str. 2011C-3493 13699303 YP_006778480.1 CDS metG NC_018658.1 1860285 1862318 R COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase complement(1860285..1862318) Escherichia coli O104:H4 str. 2011C-3493 13699304 YP_006778481.1 CDS O3K_08880 NC_018658.1 1862450 1863559 D COG0489 ATPases involved in chromosome partitioning; antiporter inner membrane protein 1862450..1863559 Escherichia coli O104:H4 str. 2011C-3493 13699305 YP_006778482.1 CDS O3K_08885 NC_018658.1 1863942 1864103 D hypothetical protein 1863942..1864103 Escherichia coli O104:H4 str. 2011C-3493 13699306 YP_006778483.1 CDS O3K_08890 NC_018658.1 1864396 1864938 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like protein 1864396..1864938 Escherichia coli O104:H4 str. 2011C-3493 13699307 YP_006778484.1 CDS O3K_08895 NC_018658.1 1865019 1865693 D COG3121 P pilus assembly protein, chaperone PapD; membrane-associated pilin chaperone 1865019..1865693 Escherichia coli O104:H4 str. 2011C-3493 13699308 YP_006778485.1 CDS O3K_08900 NC_018658.1 1865709 1868189 D COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 1865709..1868189 Escherichia coli O104:H4 str. 2011C-3493 13699309 YP_006778486.1 CDS O3K_08905 NC_018658.1 1868205 1869239 D putative fimbrial-like adhesin protein StcD 1868205..1869239 Escherichia coli O104:H4 str. 2011C-3493 13699310 YP_006778487.1 CDS O3K_08910 NC_018658.1 1869321 1869659 R COG5455 Predicted integral membrane protein; hypothetical protein complement(1869321..1869659) Escherichia coli O104:H4 str. 2011C-3493 13699311 YP_006778488.1 CDS O3K_08915 NC_018658.1 1869878 1870702 R COG2215 ABC-type uncharacterized transport system, permease component; nickel/cobalt efflux protein RcnA complement(1869878..1870702) Escherichia coli O104:H4 str. 2011C-3493 13699312 YP_006778489.1 CDS O3K_08920 NC_018658.1 1870823 1871095 D COG1937 Uncharacterized protein conserved in bacteria; transcriptional repressor RcnR to maintain nickel and cobalt homeostasis 1870823..1871095 Escherichia coli O104:H4 str. 2011C-3493 13699313 YP_006778490.1 CDS O3K_08925 NC_018658.1 1871318 1872106 D COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 1871318..1872106 Escherichia coli O104:H4 str. 2011C-3493 13699314 YP_006778491.1 CDS O3K_08930 NC_018658.1 1872103 1872903 D COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase 1872103..1872903 Escherichia coli O104:H4 str. 2011C-3493 13699315 YP_006778492.1 CDS O3K_08935 NC_018658.1 1872968 1873786 D COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); hydrolase 1872968..1873786 Escherichia coli O104:H4 str. 2011C-3493 13699316 YP_006778493.1 CDS O3K_08940 NC_018658.1 1873838 1874584 D COG2188 Transcriptional regulators; GntR family transcriptional regulator 1873838..1874584 Escherichia coli O104:H4 str. 2011C-3493 13699317 YP_006778494.1 CDS O3K_08945 NC_018658.1 1874558 1875523 R COG0524 Sugar kinases, ribokinase family; kinase complement(1874558..1875523) Escherichia coli O104:H4 str. 2011C-3493 13699318 YP_006778495.1 CDS O3K_08950 NC_018658.1 1875520 1876524 R COG1397 ADP-ribosylglycohydrolase; (phospho)hydrolase complement(1875520..1876524) Escherichia coli O104:H4 str. 2011C-3493 13699319 YP_006778496.1 CDS O3K_08955 NC_018658.1 1876521 1877798 R COG0477 Permeases of the major facilitator superfamily; putative nucleoside transporter complement(1876521..1877798) Escherichia coli O104:H4 str. 2011C-3493 13699320 YP_006778497.1 CDS O3K_08960 NC_018658.1 1878055 1879107 D COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes; fructose-bisphosphate aldolase 1878055..1879107 Escherichia coli O104:H4 str. 2011C-3493 13699321 YP_006778498.1 CDS gatY NC_018658.1 1879417 1880271 D COG0191 Fructose/tagatose bisphosphate aldolase; tagatose-bisphosphate aldolase 1879417..1880271 Escherichia coli O104:H4 str. 2011C-3493 13699322 YP_006778499.1 CDS O3K_08980 NC_018658.1 1881567 1882019 D COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system galactitol-specific transporter subunit IIA 1881567..1882019 Escherichia coli O104:H4 str. 2011C-3493 13699323 YP_006778500.1 CDS O3K_08985 NC_018658.1 1882050 1882334 D COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB 1882050..1882334 Escherichia coli O104:H4 str. 2011C-3493 13699324 YP_006778501.1 CDS O3K_08990 NC_018658.1 1882338 1883693 D COG3775 Phosphotransferase system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1882338..1883693 Escherichia coli O104:H4 str. 2011C-3493 13699325 YP_006778502.1 CDS O3K_08995 NC_018658.1 1883741 1884781 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; galactitol-1-phosphate dehydrogenase 1883741..1884781 Escherichia coli O104:H4 str. 2011C-3493 13699326 YP_006778503.1 CDS O3K_09000 NC_018658.1 1884887 1885660 D COG1349 Transcriptional regulators of sugar metabolism; galactitol utilization operon repressor 1884887..1885660 Escherichia coli O104:H4 str. 2011C-3493 13699327 YP_006778504.1 CDS O3K_09005 NC_018658.1 1885742 1886641 R COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; lipid kinase complement(1885742..1886641) Escherichia coli O104:H4 str. 2011C-3493 13699328 YP_006778505.1 CDS O3K_09010 NC_018658.1 1887056 1887373 D hypothetical protein 1887056..1887373 Escherichia coli O104:H4 str. 2011C-3493 13699329 YP_006778506.1 CDS O3K_09015 NC_018658.1 1887703 1889064 R COG0826 Collagenase and related proteases; protease complement(1887703..1889064) Escherichia coli O104:H4 str. 2011C-3493 13699330 YP_006778507.1 CDS O3K_09020 NC_018658.1 1889167 1889463 R COG3668 Plasmid stabilization system protein; plasmid stabilization system protein complement(1889167..1889463) Escherichia coli O104:H4 str. 2011C-3493 13699331 YP_006778508.1 CDS O3K_09025 NC_018658.1 1889465 1889761 R COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain; transcriptional regulator complement(1889465..1889761) Escherichia coli O104:H4 str. 2011C-3493 13699332 YP_006778509.1 CDS O3K_09030 NC_018658.1 1889970 1890302 R COG3422 Uncharacterized conserved protein; hypothetical protein complement(1889970..1890302) Escherichia coli O104:H4 str. 2011C-3493 13699333 YP_006778510.1 CDS O3K_09035 NC_018658.1 1890493 1891215 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator BaeR complement(1890493..1891215) Escherichia coli O104:H4 str. 2011C-3493 13699334 YP_006778511.1 CDS O3K_09040 NC_018658.1 1891212 1892615 R COG0642 Signal transduction histidine kinase; signal transduction histidine-protein kinase BaeS complement(1891212..1892615) Escherichia coli O104:H4 str. 2011C-3493 13699335 YP_006778512.1 CDS O3K_09045 NC_018658.1 1892612 1894027 R COG0477 Permeases of the major facilitator superfamily; transporter complement(1892612..1894027) Escherichia coli O104:H4 str. 2011C-3493 13699336 YP_006778513.1 CDS O3K_09050 NC_018658.1 1894028 1897105 R COG0841 Cation/multidrug efflux pump; multidrug efflux system subunit MdtC complement(1894028..1897105) Escherichia coli O104:H4 str. 2011C-3493 13699337 YP_006778514.1 CDS O3K_09055 NC_018658.1 1897106 1900228 R COG0841 Cation/multidrug efflux pump; multidrug efflux system subunit MdtB complement(1897106..1900228) Escherichia coli O104:H4 str. 2011C-3493 13699338 YP_006778515.1 CDS O3K_09060 NC_018658.1 1900228 1901475 R COG0845 Membrane-fusion protein; multidrug efflux system subunit MdtA complement(1900228..1901475) Escherichia coli O104:H4 str. 2011C-3493 13699339 YP_006778516.1 CDS O3K_09065 NC_018658.1 1902691 1903350 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; hypothetical protein 1902691..1903350 Escherichia coli O104:H4 str. 2011C-3493 13699340 YP_006778517.1 CDS O3K_09070 NC_018658.1 1903347 1904108 D hypothetical protein 1903347..1904108 Escherichia coli O104:H4 str. 2011C-3493 13699341 YP_006778518.1 CDS O3K_09075 NC_018658.1 1904105 1906045 D COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains; hypothetical protein 1904105..1906045 Escherichia coli O104:H4 str. 2011C-3493 13699342 YP_006778519.1 CDS O3K_09080 NC_018658.1 1906057 1907409 R COG0443 Molecular chaperone; putative chaperone complement(1906057..1907409) Escherichia coli O104:H4 str. 2011C-3493 13699343 YP_006778520.1 CDS O3K_09085 NC_018658.1 1907543 1908400 D COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; 3-methyladenine DNA glycosylase 1907543..1908400 Escherichia coli O104:H4 str. 2011C-3493 13699344 YP_006778521.1 CDS O3K_09090 NC_018658.1 1908439 1911756 R COG2202 FOG: PAS/PAC domain; putative diguanylate cyclase complement(1908439..1911756) Escherichia coli O104:H4 str. 2011C-3493 13699345 YP_006778522.1 CDS O3K_09095 NC_018658.1 1912074 1912715 D COG0572 Uridine kinase; uridine/cytidine kinase 1912074..1912715 Escherichia coli O104:H4 str. 2011C-3493 13699346 YP_006778523.1 CDS dcd NC_018658.1 1912807 1913388 D COG0717 Deoxycytidine deaminase; deoxycytidine triphosphate deaminase 1912807..1913388 Escherichia coli O104:H4 str. 2011C-3493 13699347 YP_006778524.1 CDS O3K_09105 NC_018658.1 1913410 1915263 D COG2982 Uncharacterized protein involved in outer membrane biogenesis; putative assembly protein 1913410..1915263 Escherichia coli O104:H4 str. 2011C-3493 13699348 YP_006778525.1 CDS O3K_09110 NC_018658.1 1915537 1917120 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein complement(1915537..1917120) Escherichia coli O104:H4 str. 2011C-3493 13699349 YP_006778526.1 CDS O3K_09115 NC_018658.1 1917779 1918918 D COG1596 Periplasmic protein involved in polysaccharide export; polysaccharide export protein Wza 1917779..1918918 Escherichia coli O104:H4 str. 2011C-3493 13699350 YP_006778527.1 CDS O3K_09120 NC_018658.1 1918924 1919367 D COG0394 Protein-tyrosine-phosphatase; tyrosine phosphatase 1918924..1919367 Escherichia coli O104:H4 str. 2011C-3493 13699351 YP_006778528.1 CDS O3K_09125 NC_018658.1 1919370 1921532 D COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; tyrosine kinase 1919370..1921532 Escherichia coli O104:H4 str. 2011C-3493 13699352 YP_006778529.1 CDS O3K_09130 NC_018658.1 1921710 1922549 D COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyl transferase 1921710..1922549 Escherichia coli O104:H4 str. 2011C-3493 13699353 YP_006778530.1 CDS O3K_09135 NC_018658.1 1922552 1923040 D COG1045 Serine acetyltransferase; putative acyl transferase 1922552..1923040 Escherichia coli O104:H4 str. 2011C-3493 13699354 YP_006778531.1 CDS O3K_09140 NC_018658.1 1923037 1924254 D COG0438 Glycosyltransferase; putative glycosyl transferase 1923037..1924254 Escherichia coli O104:H4 str. 2011C-3493 13699355 YP_006778532.1 CDS wcaD NC_018658.1 1924229 1925446 D putative colanic acid biosynthesis protein 1924229..1925446 Escherichia coli O104:H4 str. 2011C-3493 13699356 YP_006778533.1 CDS O3K_09150 NC_018658.1 1925457 1926203 D COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyl transferase 1925457..1926203 Escherichia coli O104:H4 str. 2011C-3493 13699357 YP_006778534.1 CDS O3K_09155 NC_018658.1 1926219 1926767 D COG0110 Acetyltransferase (isoleucine patch superfamily); putative acyl transferase 1926219..1926767 Escherichia coli O104:H4 str. 2011C-3493 13699358 YP_006778535.1 CDS O3K_09160 NC_018658.1 1926794 1927915 D COG1089 GDP-D-mannose dehydratase; GDP-mannose 4,6-dehydratase 1926794..1927915 Escherichia coli O104:H4 str. 2011C-3493 13699359 YP_006778536.1 CDS O3K_09165 NC_018658.1 1927918 1928883 D COG0451 Nucleoside-diphosphate-sugar epimerases; bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/GDP-4-dehydro-6-L-deoxygalactose reductase 1927918..1928883 Escherichia coli O104:H4 str. 2011C-3493 13699360 YP_006778537.1 CDS O3K_09170 NC_018658.1 1928886 1929365 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; GDP-mannose mannosyl hydrolase 1928886..1929365 Escherichia coli O104:H4 str. 2011C-3493 13699361 YP_006778538.1 CDS O3K_09175 NC_018658.1 1929362 1930585 D COG0438 Glycosyltransferase; putative glycosyl transferase 1929362..1930585 Escherichia coli O104:H4 str. 2011C-3493 13699362 YP_006778539.1 CDS cpsB NC_018658.1 1930588 1932024 D COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanyltransferase 1930588..1932024 Escherichia coli O104:H4 str. 2011C-3493 13699363 YP_006778540.1 CDS O3K_09185 NC_018658.1 1932393 1933763 D COG1109 Phosphomannomutase; phosphomannomutase 1932393..1933763 Escherichia coli O104:H4 str. 2011C-3493 13699364 YP_006778541.1 CDS O3K_09190 NC_018658.1 1933818 1935212 D COG2148 Sugar transferases involved in lipopolysaccharide synthesis; putative UDP-glucose lipid carrier transferase 1933818..1935212 Escherichia coli O104:H4 str. 2011C-3493 13699365 YP_006778542.1 CDS O3K_09195 NC_018658.1 1935214 1936692 D COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; colanic acid exporter 1935214..1936692 Escherichia coli O104:H4 str. 2011C-3493 13699366 YP_006778543.1 CDS O3K_09200 NC_018658.1 1936977 1938257 D COG2327 Uncharacterized conserved protein; colanic acid biosynthesis protein 1936977..1938257 Escherichia coli O104:H4 str. 2011C-3493 13699367 YP_006778544.1 CDS O3K_09205 NC_018658.1 1938254 1939474 D COG0438 Glycosyltransferase; colanic acid biosynthesis glycosyltransferase WcaL 1938254..1939474 Escherichia coli O104:H4 str. 2011C-3493 13699368 YP_006778545.1 CDS wcaM NC_018658.1 1939485 1940879 D putative colanic acid biosynthesis protein 1939485..1940879 Escherichia coli O104:H4 str. 2011C-3493 13699369 YP_006778546.1 CDS O3K_09215 NC_018658.1 1941037 1942032 D COG0451 Nucleoside-diphosphate-sugar epimerases; UDP-N-acetylglucosamine 4-epimerase 1941037..1942032 Escherichia coli O104:H4 str. 2011C-3493 13699370 YP_006778547.1 CDS O3K_09220 NC_018658.1 1942275 1943168 D COG1210 UDP-glucose pyrophosphorylase; GalU regulator GalF 1942275..1943168 Escherichia coli O104:H4 str. 2011C-3493 13699371 YP_006778548.1 CDS O3K_09225 NC_018658.1 1943529 1944149 D COG0110 Acetyltransferase (isoleucine patch superfamily); WckD 1943529..1944149 Escherichia coli O104:H4 str. 2011C-3493 13699372 YP_006778549.1 CDS O3K_09230 NC_018658.1 1944154 1945194 D COG2089 Sialic acid synthase; NnaB 1944154..1945194 Escherichia coli O104:H4 str. 2011C-3493 13699373 YP_006778550.1 CDS O3K_09235 NC_018658.1 1945200 1946465 D COG1083 CMP-N-acetylneuraminic acid synthetase; N-acylneuraminate cytidylyltransferase 1945200..1946465 Escherichia coli O104:H4 str. 2011C-3493 13699374 YP_006778551.1 CDS O3K_09240 NC_018658.1 1946462 1947625 D COG0381 UDP-N-acetylglucosamine 2-epimerase; NnaA 1946462..1947625 Escherichia coli O104:H4 str. 2011C-3493 13699375 YP_006778552.1 CDS O3K_09245 NC_018658.1 1947710 1948660 D hypothetical protein 1947710..1948660 Escherichia coli O104:H4 str. 2011C-3493 13699376 YP_006778553.1 CDS O3K_09250 NC_018658.1 1948657 1949769 D hypothetical protein 1948657..1949769 Escherichia coli O104:H4 str. 2011C-3493 13699377 YP_006778554.1 CDS O3K_09255 NC_018658.1 1949775 1950998 D COG0438 Glycosyltransferase; WbwB 1949775..1950998 Escherichia coli O104:H4 str. 2011C-3493 13699378 YP_006778555.1 CDS O3K_09260 NC_018658.1 1950998 1952275 D COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Wzx 1950998..1952275 Escherichia coli O104:H4 str. 2011C-3493 13699379 YP_006778556.1 CDS O3K_09265 NC_018658.1 1952300 1953106 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase 1952300..1953106 Escherichia coli O104:H4 str. 2011C-3493 13699380 YP_006778557.1 CDS O3K_09270 NC_018658.1 1953227 1954633 D COG0362 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase 1953227..1954633 Escherichia coli O104:H4 str. 2011C-3493 13699381 YP_006778558.1 CDS O3K_09275 NC_018658.1 1954881 1956047 D COG1004 Predicted UDP-glucose 6-dehydrogenase; UDP-glucose 6-dehydrogenase 1954881..1956047 Escherichia coli O104:H4 str. 2011C-3493 13699382 YP_006778559.1 CDS O3K_09280 NC_018658.1 1956194 1957171 D COG3765 Chain length determinant protein; chain length determinant protein WzzB 1956194..1957171 Escherichia coli O104:H4 str. 2011C-3493 13699383 YP_006778560.1 CDS O3K_09285 NC_018658.1 1957269 1957880 R COG0139 Phosphoribosyl-AMP cyclohydrolase; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase complement(1957269..1957880) Escherichia coli O104:H4 str. 2011C-3493 13699384 YP_006778561.1 CDS O3K_09290 NC_018658.1 1957874 1958650 R COG0107 Imidazoleglycerol-phosphate synthase; imidazole glycerol phosphate synthase subunit HisF complement(1957874..1958650) Escherichia coli O104:H4 str. 2011C-3493 13699385 YP_006778562.1 CDS O3K_09295 NC_018658.1 1958632 1959369 R COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase complement(1958632..1959369) Escherichia coli O104:H4 str. 2011C-3493 13699386 YP_006778563.1 CDS hisH NC_018658.1 1959369 1959959 R COG0118 Glutamine amidotransferase; imidazole glycerol phosphate synthase subunit HisH complement(1959369..1959959) Escherichia coli O104:H4 str. 2011C-3493 13699387 YP_006778564.1 CDS O3K_09305 NC_018658.1 1959959 1961026 R COG0241 Histidinol phosphatase and related phosphatases; imidazole glycerol-phosphate dehydratase/histidinol phosphatase complement(1959959..1961026) Escherichia coli O104:H4 str. 2011C-3493 13699388 YP_006778565.1 CDS O3K_09310 NC_018658.1 1961026 1962096 R COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; histidinol-phosphate aminotransferase complement(1961026..1962096) Escherichia coli O104:H4 str. 2011C-3493 13699389 YP_006778566.1 CDS hisD NC_018658.1 1962093 1963397 R COG0141 Histidinol dehydrogenase; bifunctional histidinal dehydrogenase/ histidinol dehydrogenase complement(1962093..1963397) Escherichia coli O104:H4 str. 2011C-3493 13699390 YP_006778567.1 CDS hisG NC_018658.1 1963403 1964302 R COG0040 ATP phosphoribosyltransferase; ATP phosphoribosyltransferase complement(1963403..1964302) Escherichia coli O104:H4 str. 2011C-3493 13699391 YP_006778568.1 CDS O3K_09325 NC_018658.1 1964782 1965033 D COG2161 Antitoxin of toxin-antitoxin stability system; antitoxin YefM 1964782..1965033 Escherichia coli O104:H4 str. 2011C-3493 13699392 YP_006778569.1 CDS O3K_09330 NC_018658.1 1965030 1965284 D COG4115 Uncharacterized protein conserved in bacteria; Toxin yoeB 1965030..1965284 Escherichia coli O104:H4 str. 2011C-3493 13699393 YP_006778570.1 CDS O3K_09335 NC_018658.1 1965367 1966191 D COG0451 Nucleoside-diphosphate-sugar epimerases; epimerase, with NAD(P)-binding Rossmann-fold domain 1965367..1966191 Escherichia coli O104:H4 str. 2011C-3493 13699394 YP_006778571.1 CDS O3K_09340 NC_018658.1 1966237 1967166 D COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator 1966237..1967166 Escherichia coli O104:H4 str. 2011C-3493 13699395 YP_006778572.1 CDS O3K_09345 NC_018658.1 1967433 1968791 D COG0531 Amino acid transporters; amino acid permease 1967433..1968791 Escherichia coli O104:H4 str. 2011C-3493 13699396 YP_006778573.1 CDS O3K_09350 NC_018658.1 1968970 1970028 D COG2391 Predicted transporter component; hypothetical protein 1968970..1970028 Escherichia coli O104:H4 str. 2011C-3493 13699397 YP_006778574.1 CDS O3K_09355 NC_018658.1 1970042 1970269 D COG0425 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 1970042..1970269 Escherichia coli O104:H4 str. 2011C-3493 13699398 YP_006778575.1 CDS sbcB NC_018658.1 1970312 1971736 R COG2925 Exonuclease I; exonuclease I complement(1970312..1971736) Escherichia coli O104:H4 str. 2011C-3493 13699399 YP_006778576.1 CDS dacD NC_018658.1 1971948 1973114 D COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 1971948..1973114 Escherichia coli O104:H4 str. 2011C-3493 13699400 YP_006778577.1 CDS O3K_09370 NC_018658.1 1973233 1973706 D COG3449 DNA gyrase inhibitor; DNA gyrase inhibitor 1973233..1973706 Escherichia coli O104:H4 str. 2011C-3493 13699401 YP_006778578.1 CDS O3K_09375 NC_018658.1 1973904 1974584 D COG1289 Predicted membrane protein; inner membrane protein YeeA 1973904..1974584 Escherichia coli O104:H4 str. 2011C-3493 13699402 YP_006778579.1 CDS O3K_09380 NC_018658.1 1974648 1975628 D COG3547 Transposase and inactivated derivatives; IS621 transposase 1974648..1975628 Escherichia coli O104:H4 str. 2011C-3493 13699403 YP_006778580.1 CDS O3K_09385 NC_018658.1 1975819 1976241 D inner membrane protein YeeA 1975819..1976241 Escherichia coli O104:H4 str. 2011C-3493 13699404 YP_006778581.1 CDS O3K_09390 NC_018658.1 1976413 1976742 D COG2926 Uncharacterized protein conserved in bacteria; hypothetical protein 1976413..1976742 Escherichia coli O104:H4 str. 2011C-3493 13699405 YP_006778582.1 CDS O3K_09395 NC_018658.1 1976843 1977067 R COG4917 Ethanolamine utilization protein; hypothetical protein complement(1976843..1977067) Escherichia coli O104:H4 str. 2011C-3493 13699406 YP_006778583.1 CDS O3K_09400 NC_018658.1 1977514 1977627 R hypothetical protein complement(1977514..1977627) Escherichia coli O104:H4 str. 2011C-3493 13699407 YP_006778584.1 CDS O3K_09405 NC_018658.1 1977640 1977834 R hypothetical protein complement(1977640..1977834) Escherichia coli O104:H4 str. 2011C-3493 13699408 YP_006778585.1 CDS O3K_09410 NC_018658.1 1977941 1978204 R hypothetical protein complement(1977941..1978204) Escherichia coli O104:H4 str. 2011C-3493 13699409 YP_006778586.1 CDS O3K_09415 NC_018658.1 1978293 1978661 R hypothetical protein complement(1978293..1978661) Escherichia coli O104:H4 str. 2011C-3493 13699410 YP_006778587.1 CDS O3K_09420 NC_018658.1 1978735 1978956 R hypothetical protein complement(1978735..1978956) Escherichia coli O104:H4 str. 2011C-3493 13699411 YP_006778588.1 CDS O3K_09425 NC_018658.1 1979019 1979495 R COG2003 DNA repair proteins; putative DNA repair protein complement(1979019..1979495) Escherichia coli O104:H4 str. 2011C-3493 13699412 YP_006778589.1 CDS O3K_09430 NC_018658.1 1979511 1979990 R antirestriction protein complement(1979511..1979990) Escherichia coli O104:H4 str. 2011C-3493 13699413 YP_006778590.1 CDS O3K_09435 NC_018658.1 1980072 1980893 R hypothetical protein complement(1980072..1980893) Escherichia coli O104:H4 str. 2011C-3493 13699414 YP_006778591.1 CDS O3K_09440 NC_018658.1 1981114 1981524 R hypothetical protein complement(1981114..1981524) Escherichia coli O104:H4 str. 2011C-3493 13699415 YP_006778592.1 CDS O3K_09445 NC_018658.1 1981540 1982223 R hypothetical protein complement(1981540..1982223) Escherichia coli O104:H4 str. 2011C-3493 13699416 YP_006778593.1 CDS O3K_09450 NC_018658.1 1982359 1983429 R COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein complement(1982359..1983429) Escherichia coli O104:H4 str. 2011C-3493 13699417 YP_006778594.1 CDS O3K_09455 NC_018658.1 1983426 1984331 R hypothetical protein complement(1983426..1984331) Escherichia coli O104:H4 str. 2011C-3493 13699418 YP_006778595.1 CDS O3K_09460 NC_018658.1 1984328 1986724 R COG0699 Predicted GTPases (dynamin-related); hypothetical protein complement(1984328..1986724) Escherichia coli O104:H4 str. 2011C-3493 13699419 YP_006778596.1 CDS O3K_09475 NC_018658.1 1987897 1989048 R hypothetical protein complement(1987897..1989048) Escherichia coli O104:H4 str. 2011C-3493 13699420 YP_006778597.1 CDS O3K_09480 NC_018658.1 1990252 1990527 R COG4584 Transposase and inactivated derivatives; transposase subunit complement(1990252..1990527) Escherichia coli O104:H4 str. 2011C-3493 13699421 YP_006778598.1 CDS O3K_09485 NC_018658.1 1990433 1990729 R hypothetical protein complement(1990433..1990729) Escherichia coli O104:H4 str. 2011C-3493 13699422 YP_006778599.1 CDS O3K_09490 NC_018658.1 1990616 1990999 D COG2963 Transposase and inactivated derivatives; hypothetical protein 1990616..1990999 Escherichia coli O104:H4 str. 2011C-3493 13699423 YP_006778600.1 CDS O3K_09495 NC_018658.1 1990996 1991343 D COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF 2, IS66 family protein 1990996..1991343 Escherichia coli O104:H4 str. 2011C-3493 13699424 YP_006778601.1 CDS O3K_09500 NC_018658.1 1991393 1992928 D COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF 1, IS66 family protein 1991393..1992928 Escherichia coli O104:H4 str. 2011C-3493 13699425 YP_006778602.1 CDS O3K_09505 NC_018658.1 1993887 1994495 R hypothetical protein complement(1993887..1994495) Escherichia coli O104:H4 str. 2011C-3493 13699426 YP_006778603.1 CDS O3K_09510 NC_018658.1 1994583 1994789 R COG3311 Predicted transcriptional regulator; InterPro motifs Prophage CP4-57 regulatory protein (AlpA) complement(1994583..1994789) Escherichia coli O104:H4 str. 2011C-3493 13699427 YP_006778604.1 CDS O3K_09515 NC_018658.1 1994896 1995198 D hypothetical protein 1994896..1995198 Escherichia coli O104:H4 str. 2011C-3493 13699428 YP_006778605.1 CDS O3K_09520 NC_018658.1 1995916 1996116 R hypothetical protein complement(1995916..1996116) Escherichia coli O104:H4 str. 2011C-3493 13699429 YP_006778606.1 CDS O3K_09525 NC_018658.1 1996316 1996885 D hypothetical protein 1996316..1996885 Escherichia coli O104:H4 str. 2011C-3493 13699430 YP_006778607.1 CDS O3K_09530 NC_018658.1 1997139 1997546 D COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 1997139..1997546 Escherichia coli O104:H4 str. 2011C-3493 13699431 YP_006778608.1 CDS O3K_09535 NC_018658.1 1997534 1997944 D hypothetical protein 1997534..1997944 Escherichia coli O104:H4 str. 2011C-3493 13699432 YP_006778609.1 CDS O3K_09540 NC_018658.1 1998367 1998618 R hypothetical protein complement(1998367..1998618) Escherichia coli O104:H4 str. 2011C-3493 13699433 YP_006778610.1 CDS O3K_09545 NC_018658.1 1998750 1999607 D COG3464 Transposase and inactivated derivatives; transposase, ISL3 family protein 1998750..1999607 Escherichia coli O104:H4 str. 2011C-3493 13699434 YP_006778611.1 CDS O3K_09550 NC_018658.1 1999686 1999847 D COG3464 Transposase and inactivated derivatives; transposase (part) 1999686..1999847 Escherichia coli O104:H4 str. 2011C-3493 13699435 YP_006778612.1 CDS O3K_09555 NC_018658.1 1999948 2000115 D COG0405 Gamma-glutamyltransferase; hypothetical protein 1999948..2000115 Escherichia coli O104:H4 str. 2011C-3493 13699436 YP_006778613.1 CDS O3K_09560 NC_018658.1 2000106 2000219 D hypothetical protein 2000106..2000219 Escherichia coli O104:H4 str. 2011C-3493 13699437 YP_006778614.1 CDS O3K_09565 NC_018658.1 2000259 2001293 R COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold; phosphotriesterase-related protein complement(2000259..2001293) Escherichia coli O104:H4 str. 2011C-3493 13699438 YP_006778615.1 CDS O3K_09580 NC_018658.1 2002318 2003076 R COG5426 Uncharacterized membrane protein; hypothetical protein complement(2002318..2003076) Escherichia coli O104:H4 str. 2011C-3493 13699439 YP_006778616.1 CDS O3K_09585 NC_018658.1 2003090 2004304 R COG1349 Transcriptional regulators of sugar metabolism; carbohydrate kinase complement(2003090..2004304) Escherichia coli O104:H4 str. 2011C-3493 13699440 YP_006778617.1 CDS O3K_09590 NC_018658.1 2004500 2004616 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(2004500..2004616) Escherichia coli O104:H4 str. 2011C-3493 13699441 YP_006778618.1 CDS O3K_09595 NC_018658.1 2004556 2005047 R hypothetical protein complement(2004556..2005047) Escherichia coli O104:H4 str. 2011C-3493 13699442 YP_006778619.1 CDS O3K_09600 NC_018658.1 2005738 2005902 D hypothetical protein 2005738..2005902 Escherichia coli O104:H4 str. 2011C-3493 13699443 YP_006778620.1 CDS cobU NC_018658.1 2006367 2006912 D COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 2006367..2006912 Escherichia coli O104:H4 str. 2011C-3493 13699444 YP_006778621.1 CDS cobS NC_018658.1 2006909 2007652 D COG0368 Cobalamin-5-phosphate synthase; cobalamin synthase 2006909..2007652 Escherichia coli O104:H4 str. 2011C-3493 13699445 YP_006778622.1 CDS cobT NC_018658.1 2007664 2008743 D COG2038 NaMN:DMB phosphoribosyltransferase; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2007664..2008743 Escherichia coli O104:H4 str. 2011C-3493 13699446 YP_006778623.1 CDS O3K_09620 NC_018658.1 2008808 2009740 D COG1376 Uncharacterized protein conserved in bacteria; L,D-transpeptidase 2008808..2009740 Escherichia coli O104:H4 str. 2011C-3493 13699447 YP_006778624.1 CDS O3K_09625 NC_018658.1 2010198 2011115 D COG0583 Transcriptional regulator; nitrogen assimilation transcriptional regulator 2010198..2011115 Escherichia coli O104:H4 str. 2011C-3493 13699449 YP_006778625.1 CDS cbl NC_018658.1 2011217 2012167 D COG0583 Transcriptional regulator; transcriptional regulator Cbl 2011217..2012167 Escherichia coli O104:H4 str. 2011C-3493 13699450 YP_006778626.1 CDS O3K_09635 NC_018658.1 2012288 2013928 D COG0534 Na+-driven multidrug efflux pump; MATE family multidrug exporter 2012288..2013928 Escherichia coli O104:H4 str. 2011C-3493 13699452 YP_006778627.1 CDS O3K_09640 NC_018658.1 2014556 2015272 R COG0217 Uncharacterized conserved protein; hypothetical protein complement(2014556..2015272) Escherichia coli O104:H4 str. 2011C-3493 13699454 YP_006778628.1 CDS O3K_09645 NC_018658.1 2015615 2017069 R COG0775 Nucleoside phosphorylase; AMP nucleosidase complement(2015615..2017069) Escherichia coli O104:H4 str. 2011C-3493 13699455 YP_006778629.1 CDS O3K_09650 NC_018658.1 2017171 2018487 R COG0477 Permeases of the major facilitator superfamily; shikimate transporter complement(2017171..2018487) Escherichia coli O104:H4 str. 2011C-3493 13699456 YP_006778630.1 CDS O3K_09655 NC_018658.1 2018802 2019854 D COG0859 ADP-heptose:LPS heptosyltransferase; hypothetical protein 2018802..2019854 Escherichia coli O104:H4 str. 2011C-3493 13699457 YP_006778631.1 CDS O3K_09670 NC_018658.1 2021976 2022116 R hypothetical protein complement(2021976..2022116) Escherichia coli O104:H4 str. 2011C-3493 13699458 YP_006778632.1 CDS O3K_09675 NC_018658.1 2022073 2022495 R hypothetical protein complement(2022073..2022495) Escherichia coli O104:H4 str. 2011C-3493 13699459 YP_006778633.1 CDS O3K_09680 NC_018658.1 2023473 2025494 R COG1629 Outer membrane receptor proteins, mostly Fe transport; Yersiniabactin/pesticin outer membrane receptor (IRPC) complement(2023473..2025494) Escherichia coli O104:H4 str. 2011C-3493 13699460 YP_006778634.1 CDS O3K_09685 NC_018658.1 2025625 2027202 R COG1021 Peptide arylation enzymes; salicyl-AMP ligase YbtE complement(2025625..2027202) Escherichia coli O104:H4 str. 2011C-3493 13699461 YP_006778635.1 CDS O3K_09690 NC_018658.1 2027206 2028009 R COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis; siderophore biosynthetic protein complement(2027206..2028009) Escherichia coli O104:H4 str. 2011C-3493 13699462 YP_006778636.1 CDS O3K_09695 NC_018658.1 2028006 2029106 R COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis; Thiazolinyl-S-HMWP1 reductase YbtU complement(2028006..2029106) Escherichia coli O104:H4 str. 2011C-3493 13699463 YP_006778637.1 CDS O3K_09700 NC_018658.1 2029103 2038594 R COG3321 Polyketide synthase modules and related proteins; High-molecular-weight nonribosomal peptide/polyketide synthetase 1 (HMWP1) complement(2029103..2038594) Escherichia coli O104:H4 str. 2011C-3493 13699464 YP_006778638.1 CDS O3K_09705 NC_018658.1 2038682 2044789 R COG1020 Non-ribosomal peptide synthetase modules and related proteins; High-molecular-weight nonribosomal peptide/polyketide synthetase 2 (HMWP2) complement(2038682..2044789) Escherichia coli O104:H4 str. 2011C-3493 13699465 YP_006778639.1 CDS O3K_09710 NC_018658.1 2044980 2045939 R COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator complement(2044980..2045939) Escherichia coli O104:H4 str. 2011C-3493 13699466 YP_006778640.1 CDS O3K_09715 NC_018658.1 2046106 2047908 D COG1132 ABC-type multidrug transport system, ATPase and permease components; yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtP 2046106..2047908 Escherichia coli O104:H4 str. 2011C-3493 13699467 YP_006778641.1 CDS O3K_09720 NC_018658.1 2047895 2049697 D COG1132 ABC-type multidrug transport system, ATPase and permease components; yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtQ 2047895..2049697 Escherichia coli O104:H4 str. 2011C-3493 13699468 YP_006778642.1 CDS O3K_09725 NC_018658.1 2049690 2050970 D COG0477 Permeases of the major facilitator superfamily; yersiniabactin-iron transporter permease YbtX 2049690..2050970 Escherichia coli O104:H4 str. 2011C-3493 13699469 YP_006778643.1 CDS O3K_09730 NC_018658.1 2050998 2052302 D COG0147 Anthranilate/para-aminobenzoate synthases component I; salicylate synthase Irp9 2050998..2052302 Escherichia coli O104:H4 str. 2011C-3493 13699470 YP_006778644.1 CDS O3K_09735 NC_018658.1 2052496 2053758 R COG0582 Integrase; integrase complement(2052496..2053758) Escherichia coli O104:H4 str. 2011C-3493 13699471 YP_006778645.1 CDS O3K_09740 NC_018658.1 2054096 2054893 R COG3228 Uncharacterized protein conserved in bacteria; DgsA anti-repressor MtfA complement(2054096..2054893) Escherichia coli O104:H4 str. 2011C-3493 13699473 YP_006778646.1 CDS O3K_09745 NC_018658.1 2055746 2056396 R COG3443 Predicted periplasmic or secreted protein; zinc/cadmium-binding protein complement(2055746..2056396) Escherichia coli O104:H4 str. 2011C-3493 13699475 YP_006778647.1 CDS O3K_09750 NC_018658.1 2056653 2057288 R COG2717 Predicted membrane protein; putative sulfite oxidase subunit YedZ complement(2056653..2057288) Escherichia coli O104:H4 str. 2011C-3493 13699476 YP_006778648.1 CDS O3K_09755 NC_018658.1 2057289 2058293 R COG2041 Sulfite oxidase and related enzymes; TMAO/DMSO reductase complement(2057289..2058293) Escherichia coli O104:H4 str. 2011C-3493 13699477 YP_006778649.1 CDS O3K_09760 NC_018658.1 2058402 2058815 R COG2351 Transthyretin-like protein; hydroxyisourate hydrolase complement(2058402..2058815) Escherichia coli O104:H4 str. 2011C-3493 13699478 YP_006778650.1 CDS O3K_09765 NC_018658.1 2058948 2059619 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulatory protein YedW 2058948..2059619 Escherichia coli O104:H4 str. 2011C-3493 13699479 YP_006778651.1 CDS O3K_09770 NC_018658.1 2059619 2060977 D COG0642 Signal transduction histidine kinase; sensory kinase in two-component regulatory system with YedW 2059619..2060977 Escherichia coli O104:H4 str. 2011C-3493 13699480 YP_006778652.1 CDS O3K_09775 NC_018658.1 2061075 2061926 R COG0693 Putative intracellular protease/amidase; chaperone protein HchA complement(2061075..2061926) Escherichia coli O104:H4 str. 2011C-3493 13699481 YP_006778653.1 CDS O3K_09780 NC_018658.1 2062012 2062287 D COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA 2062012..2062287 Escherichia coli O104:H4 str. 2011C-3493 13699482 YP_006778654.1 CDS O3K_09785 NC_018658.1 2062206 2062709 D COG1662 Transposase and inactivated derivatives, IS1 family; putative IS1 transposase InsAB' 2062206..2062709 Escherichia coli O104:H4 str. 2011C-3493 13699483 YP_006778655.1 CDS O3K_09790 NC_018658.1 2063215 2063901 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(2063215..2063901) Escherichia coli O104:H4 str. 2011C-3493 13699484 YP_006778656.1 CDS O3K_09795 NC_018658.1 2063843 2064034 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(2063843..2064034) Escherichia coli O104:H4 str. 2011C-3493 13699485 YP_006778657.1 CDS O3K_09800 NC_018658.1 2064174 2065325 D COG2826 Transposase and inactivated derivatives, IS30 family; transposase for IS30 2064174..2065325 Escherichia coli O104:H4 str. 2011C-3493 13699486 YP_006778658.1 CDS O3K_09805 NC_018658.1 2065245 2065595 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(2065245..2065595) Escherichia coli O104:H4 str. 2011C-3493 13699487 YP_006778659.1 CDS O3K_09820 NC_018658.1 2067272 2067637 D COG0477 Permeases of the major facilitator superfamily; inner membrane protein 2067272..2067637 Escherichia coli O104:H4 str. 2011C-3493 13699488 YP_006778660.1 CDS O3K_09825 NC_018658.1 2067677 2068372 D COG1418 Predicted HD superfamily hydrolase; hydrolase 2067677..2068372 Escherichia coli O104:H4 str. 2011C-3493 13699489 YP_006778661.1 CDS O3K_09830 NC_018658.1 2068439 2069857 D COG0270 Site-specific DNA methylase; DNA cytosine methylase 2068439..2069857 Escherichia coli O104:H4 str. 2011C-3493 13699490 YP_006778662.1 CDS O3K_09835 NC_018658.1 2069838 2070308 D COG3727 DNA G:T-mismatch repair endonuclease; very short patch repair protein 2069838..2070308 Escherichia coli O104:H4 str. 2011C-3493 13699491 YP_006778663.1 CDS O3K_09840 NC_018658.1 2070297 2071217 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; putative DMT superfamily transporter inner membrane protein complement(2070297..2071217) Escherichia coli O104:H4 str. 2011C-3493 13699492 YP_006778664.1 CDS O3K_09845 NC_018658.1 2071390 2072307 D COG2354 Uncharacterized protein conserved in bacteria; hypothetical protein 2071390..2072307 Escherichia coli O104:H4 str. 2011C-3493 13699493 YP_006778665.1 CDS O3K_09850 NC_018658.1 2072386 2072568 D COG5475 Uncharacterized small protein; hypothetical protein 2072386..2072568 Escherichia coli O104:H4 str. 2011C-3493 13699494 YP_006778666.1 CDS O3K_09855 NC_018658.1 2072757 2073674 D diguanylate cyclase 2072757..2073674 Escherichia coli O104:H4 str. 2011C-3493 13699495 YP_006778667.1 CDS O3K_09860 NC_018658.1 2073678 2074433 D COG2199 FOG: GGDEF domain; diguanylate cyclase 2073678..2074433 Escherichia coli O104:H4 str. 2011C-3493 13699496 YP_006778668.1 CDS O3K_09865 NC_018658.1 2074430 2075245 R COG3769 Predicted hydrolase (HAD superfamily); mannosyl-3-phosphoglycerate phosphatase complement(2074430..2075245) Escherichia coli O104:H4 str. 2011C-3493 13699497 YP_006778669.1 CDS O3K_09870 NC_018658.1 2075544 2075771 R hypothetical protein complement(2075544..2075771) Escherichia coli O104:H4 str. 2011C-3493 13699498 YP_006778670.1 CDS O3K_09875 NC_018658.1 2075934 2076122 D hypothetical protein 2075934..2076122 Escherichia coli O104:H4 str. 2011C-3493 13699499 YP_006778671.1 CDS rcsA NC_018658.1 2076166 2076789 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; colanic acid capsular biosynthesis activation protein A complement(2076166..2076789) Escherichia coli O104:H4 str. 2011C-3493 13699500 YP_006778672.1 CDS fliR NC_018658.1 2077079 2077864 R COG1684 Flagellar biosynthesis pathway, component FliR; flagellar biosynthesis protein FliR complement(2077079..2077864) Escherichia coli O104:H4 str. 2011C-3493 13699501 YP_006778673.1 CDS fliQ NC_018658.1 2077873 2078142 R COG1987 Flagellar biosynthesis pathway, component FliQ; flagellar biosynthesis protein FliQ complement(2077873..2078142) Escherichia coli O104:H4 str. 2011C-3493 13699502 YP_006778674.1 CDS fliP NC_018658.1 2078152 2078889 R COG1338 Flagellar biosynthesis pathway, component FliP; flagellar biosynthesis protein FliP complement(2078152..2078889) Escherichia coli O104:H4 str. 2011C-3493 13699503 YP_006778675.1 CDS O3K_09900 NC_018658.1 2078889 2079254 R COG3190 Flagellar biogenesis protein; flagellar biosynthesis protein FliO complement(2078889..2079254) Escherichia coli O104:H4 str. 2011C-3493 13699504 YP_006778676.1 CDS fliN NC_018658.1 2079257 2079670 R COG1886 Flagellar motor switch/type III secretory pathway protein; flagellar motor switch protein FliN complement(2079257..2079670) Escherichia coli O104:H4 str. 2011C-3493 13699505 YP_006778677.1 CDS fliM NC_018658.1 2079667 2080671 R COG1868 Flagellar motor switch protein; flagellar motor switch protein FliM complement(2079667..2080671) Escherichia coli O104:H4 str. 2011C-3493 13699506 YP_006778678.1 CDS fliL NC_018658.1 2080676 2081140 R COG1580 Flagellar basal body-associated protein; flagellar basal body-associated protein FliL complement(2080676..2081140) Escherichia coli O104:H4 str. 2011C-3493 13699507 YP_006778679.1 CDS O3K_09920 NC_018658.1 2081245 2082372 R COG3144 Flagellar hook-length control protein; flagellar hook-length control protein complement(2081245..2082372) Escherichia coli O104:H4 str. 2011C-3493 13699508 YP_006778680.1 CDS fliJ NC_018658.1 2082369 2082812 R COG2882 Flagellar biosynthesis chaperone; flagellar biosynthesis chaperone complement(2082369..2082812) Escherichia coli O104:H4 str. 2011C-3493 13699509 YP_006778681.1 CDS fliI NC_018658.1 2082831 2084204 R COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; flagellum-specific ATP synthase complement(2082831..2084204) Escherichia coli O104:H4 str. 2011C-3493 13699510 YP_006778682.1 CDS fliH NC_018658.1 2084204 2084890 R COG1317 Flagellar biosynthesis/type III secretory pathway protein; flagellar assembly protein H complement(2084204..2084890) Escherichia coli O104:H4 str. 2011C-3493 13699511 YP_006778683.1 CDS fliG NC_018658.1 2084883 2085878 R COG1536 Flagellar motor switch protein; flagellar motor switch protein G complement(2084883..2085878) Escherichia coli O104:H4 str. 2011C-3493 13699512 YP_006778684.1 CDS fliF NC_018658.1 2085871 2087529 R COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; flagellar MS-ring protein complement(2085871..2087529) Escherichia coli O104:H4 str. 2011C-3493 13699513 YP_006778685.1 CDS fliE NC_018658.1 2087744 2088058 D COG1677 Flagellar hook-basal body protein; flagellar hook-basal body protein FliE 2087744..2088058 Escherichia coli O104:H4 str. 2011C-3493 13699514 YP_006778686.1 CDS emrE NC_018658.1 2088402 2088734 D COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein 2088402..2088734 Escherichia coli O104:H4 str. 2011C-3493 13699515 YP_006778687.1 CDS O3K_09960 NC_018658.1 2088903 2089454 D COG1881 Phospholipid-binding protein; putative kinase inhibitor 2088903..2089454 Escherichia coli O104:H4 str. 2011C-3493 13699516 YP_006778688.1 CDS O3K_09965 NC_018658.1 2089464 2090261 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator, DLP12 prophage 2089464..2090261 Escherichia coli O104:H4 str. 2011C-3493 13699517 YP_006778689.1 CDS O3K_09970 NC_018658.1 2090418 2090987 R COG1943 Transposase and inactivated derivatives; IS609 family protein; transposase ORF A, IS609 family protein complement(2090418..2090987) Escherichia coli O104:H4 str. 2011C-3493 13699518 YP_006778690.1 CDS O3K_09975 NC_018658.1 2091176 2091673 R COG2135 Uncharacterized conserved protein; hypothetical protein complement(2091176..2091673) Escherichia coli O104:H4 str. 2011C-3493 13699519 YP_006778691.1 CDS O3K_09980 NC_018658.1 2091782 2092015 R COG0425 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein complement(2091782..2092015) Escherichia coli O104:H4 str. 2011C-3493 13699520 YP_006778692.1 CDS O3K_09985 NC_018658.1 2092012 2093217 R COG2391 Predicted transporter component; inner membrane protein complement(2092012..2093217) Escherichia coli O104:H4 str. 2011C-3493 13699521 YP_006778693.1 CDS O3K_09990 NC_018658.1 2093404 2093817 D lipoprotein 2093404..2093817 Escherichia coli O104:H4 str. 2011C-3493 13699522 YP_006778694.1 CDS O3K_09995 NC_018658.1 2093851 2095338 R COG0366 Glycosidases; alpha-amylase complement(2093851..2095338) Escherichia coli O104:H4 str. 2011C-3493 13699523 YP_006778695.1 CDS O3K_10000 NC_018658.1 2095416 2095781 R COG1012 NAD-dependent aldehyde dehydrogenases; flagellar biosynthesis protein FliT complement(2095416..2095781) Escherichia coli O104:H4 str. 2011C-3493 13699524 YP_006778696.1 CDS fliS NC_018658.1 2095781 2096191 R COG1516 Flagellin-specific chaperone FliS; flagellar protein FliS complement(2095781..2096191) Escherichia coli O104:H4 str. 2011C-3493 13699525 YP_006778697.1 CDS fliD NC_018658.1 2096207 2097622 R COG1345 Flagellar capping protein; flagellar capping protein complement(2096207..2097622) Escherichia coli O104:H4 str. 2011C-3493 13699526 YP_006778698.1 CDS O3K_10015 NC_018658.1 2097870 2098919 D COG1344 Flagellin and related hook-associated proteins; Flagellin 2097870..2098919 Escherichia coli O104:H4 str. 2011C-3493 13699527 YP_006778699.1 CDS fliA NC_018658.1 2099083 2099802 D COG1191 DNA-directed RNA polymerase specialized sigma subunit; flagellar biosynthesis sigma factor 2099083..2099802 Escherichia coli O104:H4 str. 2011C-3493 13699528 YP_006778700.1 CDS O3K_10025 NC_018658.1 2099848 2100399 D flagella biosynthesis protein FliZ 2099848..2100399 Escherichia coli O104:H4 str. 2011C-3493 13699529 YP_006778701.1 CDS O3K_10030 NC_018658.1 2100487 2101287 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; cystine transporter subunit 2100487..2101287 Escherichia coli O104:H4 str. 2011C-3493 13699530 YP_006778702.1 CDS O3K_10035 NC_018658.1 2101392 2102378 D COG2515 1-aminocyclopropane-1-carboxylate deaminase; D-cysteine desulfhydrase 2101392..2102378 Escherichia coli O104:H4 str. 2011C-3493 13699531 YP_006778703.1 CDS O3K_10040 NC_018658.1 2102393 2103061 D COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 2102393..2103061 Escherichia coli O104:H4 str. 2011C-3493 13699532 YP_006778704.1 CDS O3K_10045 NC_018658.1 2103058 2103810 D COG1126 ABC-type polar amino acid transport system, ATPase component; amino-acid ABC transporter ATP-binding protein YecC 2103058..2103810 Escherichia coli O104:H4 str. 2011C-3493 13699533 YP_006778705.1 CDS O3K_10050 NC_018658.1 2104040 2104762 D COG2771 DNA-binding HTH domain-containing proteins; DNA-binding transcriptional activator SdiA 2104040..2104762 Escherichia coli O104:H4 str. 2011C-3493 13699534 YP_006778706.1 CDS O3K_10055 NC_018658.1 2104830 2105054 R hypothetical protein complement(2104830..2105054) Escherichia coli O104:H4 str. 2011C-3493 13699535 YP_006778707.1 CDS O3K_10060 NC_018658.1 2105041 2105217 R hypothetical protein complement(2105041..2105217) Escherichia coli O104:H4 str. 2011C-3493 13699536 YP_006778708.1 CDS O3K_10065 NC_018658.1 2105513 2106169 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator 2105513..2106169 Escherichia coli O104:H4 str. 2011C-3493 13699537 YP_006778709.1 CDS uvrC NC_018658.1 2106166 2107998 D COG0322 Nuclease subunit of the excinuclease complex; excinuclease ABC subunit C 2106166..2107998 Escherichia coli O104:H4 str. 2011C-3493 13699538 YP_006778710.1 CDS O3K_10075 NC_018658.1 2108055 2108603 D COG0558 Phosphatidylglycerophosphate synthase; phosphatidylglycerophosphate synthetase 2108055..2108603 Escherichia coli O104:H4 str. 2011C-3493 13699539 YP_006778711.1 CDS O3K_10080 NC_018658.1 2109253 2109918 D COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; hypothetical protein 2109253..2109918 Escherichia coli O104:H4 str. 2011C-3493 13699543 YP_006778712.1 CDS O3K_10085 NC_018658.1 2109980 2111191 R COG0814 Amino acid permeases; tyrosine transporter TyrP complement(2109980..2111191) Escherichia coli O104:H4 str. 2011C-3493 13699544 YP_006778713.1 CDS O3K_10090 NC_018658.1 2111381 2111620 D hypothetical protein 2111381..2111620 Escherichia coli O104:H4 str. 2011C-3493 13699545 YP_006778714.1 CDS O3K_10095 NC_018658.1 2111658 2112155 R COG1528 Ferritin-like protein; ferritin complement(2111658..2112155) Escherichia coli O104:H4 str. 2011C-3493 13699546 YP_006778715.1 CDS O3K_10100 NC_018658.1 2112327 2112650 R hypothetical protein complement(2112327..2112650) Escherichia coli O104:H4 str. 2011C-3493 13699547 YP_006778716.1 CDS O3K_10105 NC_018658.1 2113114 2113365 D hypothetical protein 2113114..2113365 Escherichia coli O104:H4 str. 2011C-3493 13699548 YP_006778717.1 CDS O3K_10110 NC_018658.1 2113444 2113947 R COG1528 Ferritin-like protein; ferritin-like protein complement(2113444..2113947) Escherichia coli O104:H4 str. 2011C-3493 13699549 YP_006778718.1 CDS O3K_10115 NC_018658.1 2114744 2115733 D COG1879 ABC-type sugar transport system, periplasmic component; L-arabinose ABC transporter substrate-binding protein 2114744..2115733 Escherichia coli O104:H4 str. 2011C-3493 13699550 YP_006778719.1 CDS araG NC_018658.1 2115803 2117317 D COG1129 ABC-type sugar transport system, ATPase component; L-arabinose transporter ATP-binding protein 2115803..2117317 Escherichia coli O104:H4 str. 2011C-3493 13699551 YP_006778720.1 CDS araH NC_018658.1 2117332 2118318 D COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; L-arabinose transporter permease 2117332..2118318 Escherichia coli O104:H4 str. 2011C-3493 13699552 YP_006778721.1 CDS O3K_10130 NC_018658.1 2118485 2119285 D COG1877 Trehalose-6-phosphatase; trehalose-6-phosphate phosphatase 2118485..2119285 Escherichia coli O104:H4 str. 2011C-3493 13699553 YP_006778722.1 CDS O3K_10135 NC_018658.1 2119260 2120684 D COG0380 Trehalose-6-phosphate synthase; trehalose-6-phosphate synthase 2119260..2120684 Escherichia coli O104:H4 str. 2011C-3493 13699554 YP_006778723.1 CDS O3K_10140 NC_018658.1 2120691 2121119 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspC complement(2120691..2121119) Escherichia coli O104:H4 str. 2011C-3493 13699555 YP_006778724.1 CDS O3K_10145 NC_018658.1 2121898 2122248 D transcriptional activator FlhD 2121898..2122248 Escherichia coli O104:H4 str. 2011C-3493 13699556 YP_006778725.1 CDS O3K_10150 NC_018658.1 2122251 2122829 D transcriptional activator FlhC 2122251..2122829 Escherichia coli O104:H4 str. 2011C-3493 13699557 YP_006778726.1 CDS O3K_10155 NC_018658.1 2122956 2123843 D COG1291 Flagellar motor component; flagellar motor protein MotA 2122956..2123843 Escherichia coli O104:H4 str. 2011C-3493 13699558 YP_006778727.1 CDS motB NC_018658.1 2123840 2124766 D COG1360 Flagellar motor protein; flagellar motor protein MotB 2123840..2124766 Escherichia coli O104:H4 str. 2011C-3493 13699559 YP_006778728.1 CDS O3K_10165 NC_018658.1 2124771 2126735 D COG0643 Chemotaxis protein histidine kinase and related kinases; chemotaxis protein CheA 2124771..2126735 Escherichia coli O104:H4 str. 2011C-3493 13699560 YP_006778729.1 CDS O3K_10170 NC_018658.1 2126756 2127259 D COG0835 Chemotaxis signal transduction protein; purine-binding chemotaxis protein 2126756..2127259 Escherichia coli O104:H4 str. 2011C-3493 13699561 YP_006778730.1 CDS O3K_10175 NC_018658.1 2127404 2129065 D COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein II 2127404..2129065 Escherichia coli O104:H4 str. 2011C-3493 13699562 YP_006778731.1 CDS O3K_10180 NC_018658.1 2129111 2130712 D COG0840 Methyl-accepting chemotaxis protein; methyl-accepting protein IV 2129111..2130712 Escherichia coli O104:H4 str. 2011C-3493 13699563 YP_006778732.1 CDS O3K_10185 NC_018658.1 2130731 2131591 D COG1352 Methylase of chemotaxis methyl-accepting proteins; chemotaxis methyltransferase CheR 2130731..2131591 Escherichia coli O104:H4 str. 2011C-3493 13699564 YP_006778733.1 CDS O3K_10190 NC_018658.1 2131594 2132643 D COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; chemotaxis-specific methylesterase 2131594..2132643 Escherichia coli O104:H4 str. 2011C-3493 13699565 YP_006778734.1 CDS O3K_10195 NC_018658.1 2132658 2133047 D COG0784 FOG: CheY-like receiver; chemotaxis regulatory protein CheY 2132658..2133047 Escherichia coli O104:H4 str. 2011C-3493 13699566 YP_006778735.1 CDS O3K_10200 NC_018658.1 2133058 2133702 D COG3143 Chemotaxis protein; chemotaxis regulator CheZ 2133058..2133702 Escherichia coli O104:H4 str. 2011C-3493 13699567 YP_006778736.1 CDS flhB NC_018658.1 2133904 2135052 D COG1377 Flagellar biosynthesis pathway, component FlhB; flagellar biosynthesis protein FlhB 2133904..2135052 Escherichia coli O104:H4 str. 2011C-3493 13699568 YP_006778737.1 CDS flhA NC_018658.1 2135045 2137123 D COG1298 Flagellar biosynthesis pathway, component FlhA; flagellar biosynthesis protein FlhA 2135045..2137123 Escherichia coli O104:H4 str. 2011C-3493 13699569 YP_006778738.1 CDS O3K_10215 NC_018658.1 2137123 2137515 D flagellar protein FlhE 2137123..2137515 Escherichia coli O104:H4 str. 2011C-3493 13699570 YP_006778739.1 CDS O3K_10220 NC_018658.1 2137635 2138123 R COG3755 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2137635..2138123) Escherichia coli O104:H4 str. 2011C-3493 13699571 YP_006778740.1 CDS argS NC_018658.1 2138300 2140033 R COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase complement(2138300..2140033) Escherichia coli O104:H4 str. 2011C-3493 13699572 YP_006778741.1 CDS O3K_10230 NC_018658.1 2140249 2140815 D COG3102 Uncharacterized protein conserved in bacteria; hypothetical protein 2140249..2140815 Escherichia coli O104:H4 str. 2011C-3493 13699573 YP_006778742.1 CDS O3K_10235 NC_018658.1 2140829 2141575 D COG3142 Uncharacterized protein involved in copper resistance; copper homeostasis protein CutC 2140829..2141575 Escherichia coli O104:H4 str. 2011C-3493 13699574 YP_006778743.1 CDS O3K_10240 NC_018658.1 2141963 2143063 D COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; TMAO reductase III (TorYZ), cytochrome c-type subunit TorY 2141963..2143063 Escherichia coli O104:H4 str. 2011C-3493 13699575 YP_006778744.1 CDS O3K_10245 NC_018658.1 2143088 2145517 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; trimethylamine N-oxide reductase system III, catalytic subunit 2143088..2145517 Escherichia coli O104:H4 str. 2011C-3493 13699576 YP_006778745.1 CDS O3K_10250 NC_018658.1 2145683 2146654 R COG0500 SAM-dependent methyltransferases; tRNA mo(5)U34 methyltransferase complement(2145683..2146654) Escherichia coli O104:H4 str. 2011C-3493 13699577 YP_006778746.1 CDS O3K_10255 NC_018658.1 2146651 2147394 R COG0500 SAM-dependent methyltransferases; tRNA cmo(5)U34 methyltransferase complement(2146651..2147394) Escherichia coli O104:H4 str. 2011C-3493 13699578 YP_006778747.1 CDS O3K_10260 NC_018658.1 2147435 2147830 R COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily; inner membrane protein complement(2147435..2147830) Escherichia coli O104:H4 str. 2011C-3493 13699579 YP_006778748.1 CDS O3K_10265 NC_018658.1 2147883 2148608 R COG1801 Uncharacterized conserved protein; hypothetical protein complement(2147883..2148608) Escherichia coli O104:H4 str. 2011C-3493 13699580 YP_006778749.1 CDS O3K_10270 NC_018658.1 2148635 2149945 R COG0582 Integrase; integrase complement(2148635..2149945) Escherichia coli O104:H4 str. 2011C-3493 13699581 YP_006778750.1 CDS O3K_10275 NC_018658.1 2150001 2150237 R putative excisionase complement(2150001..2150237) Escherichia coli O104:H4 str. 2011C-3493 13699582 YP_006778751.1 CDS O3K_10280 NC_018658.1 2150246 2150392 R hypothetical protein complement(2150246..2150392) Escherichia coli O104:H4 str. 2011C-3493 13699583 YP_006778752.1 CDS O3K_10285 NC_018658.1 2150396 2150638 R hypothetical protein complement(2150396..2150638) Escherichia coli O104:H4 str. 2011C-3493 13699584 YP_006778753.1 CDS O3K_10290 NC_018658.1 2150723 2151481 R hypothetical protein complement(2150723..2151481) Escherichia coli O104:H4 str. 2011C-3493 13699585 YP_006778754.1 CDS O3K_10295 NC_018658.1 2151478 2151993 R hypothetical protein complement(2151478..2151993) Escherichia coli O104:H4 str. 2011C-3493 13699586 YP_006778755.1 CDS O3K_10300 NC_018658.1 2151995 2152543 R putative EA22-like protein complement(2151995..2152543) Escherichia coli O104:H4 str. 2011C-3493 13699587 YP_006778756.1 CDS O3K_10305 NC_018658.1 2152540 2152779 R hypothetical protein complement(2152540..2152779) Escherichia coli O104:H4 str. 2011C-3493 13699588 YP_006778757.1 CDS O3K_10310 NC_018658.1 2152772 2152975 R hypothetical protein complement(2152772..2152975) Escherichia coli O104:H4 str. 2011C-3493 13699589 YP_006778758.1 CDS O3K_10315 NC_018658.1 2152972 2153334 R CPS-53 (KpLE1) prophage protein complement(2152972..2153334) Escherichia coli O104:H4 str. 2011C-3493 13699590 YP_006778759.1 CDS O3K_10320 NC_018658.1 2153325 2153861 R COG1896 Predicted hydrolases of HD superfamily; hypothetical protein complement(2153325..2153861) Escherichia coli O104:H4 str. 2011C-3493 13699591 YP_006778760.1 CDS O3K_10325 NC_018658.1 2153989 2154813 R COG5532 Uncharacterized conserved protein; CPS-53 (KpLE1) prophage protein complement(2153989..2154813) Escherichia coli O104:H4 str. 2011C-3493 13699592 YP_006778761.1 CDS O3K_10330 NC_018658.1 2155944 2156636 R COG2932 Predicted transcriptional regulator; putative repressor protein CI complement(2155944..2156636) Escherichia coli O104:H4 str. 2011C-3493 13699593 YP_006778762.1 CDS O3K_10335 NC_018658.1 2156734 2156994 D COG1396 Predicted transcriptional regulators; hypothetical protein 2156734..2156994 Escherichia coli O104:H4 str. 2011C-3493 13699594 YP_006778763.1 CDS O3K_10340 NC_018658.1 2156987 2157544 D nucleic acid-binding protein, e14 prophage 2156987..2157544 Escherichia coli O104:H4 str. 2011C-3493 13699595 YP_006778764.1 CDS O3K_10345 NC_018658.1 2157541 2158686 D COG3646 Uncharacterized phage-encoded protein; hypothetical protein 2157541..2158686 Escherichia coli O104:H4 str. 2011C-3493 13699596 YP_006778765.1 CDS O3K_10350 NC_018658.1 2158683 2158907 D hypothetical protein 2158683..2158907 Escherichia coli O104:H4 str. 2011C-3493 13699597 YP_006778766.1 CDS O3K_10355 NC_018658.1 2158904 2159722 D replication protein from phage 2158904..2159722 Escherichia coli O104:H4 str. 2011C-3493 13699598 YP_006778767.1 CDS O3K_10360 NC_018658.1 2159719 2160213 D hypothetical protein 2159719..2160213 Escherichia coli O104:H4 str. 2011C-3493 13699599 YP_006778768.1 CDS O3K_10365 NC_018658.1 2160213 2160866 D phage AdoMet-dependent methyltransferase 2160213..2160866 Escherichia coli O104:H4 str. 2011C-3493 13699600 YP_006778769.1 CDS O3K_10370 NC_018658.1 2160863 2161189 D COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); LexA repressor 2160863..2161189 Escherichia coli O104:H4 str. 2011C-3493 13699601 YP_006778770.1 CDS O3K_10375 NC_018658.1 2161186 2161581 D COG4570 Holliday junction resolvase; putative Crossover junction endodeoxyribonuclease 2161186..2161581 Escherichia coli O104:H4 str. 2011C-3493 13699602 YP_006778771.1 CDS O3K_10380 NC_018658.1 2161744 2162559 D KilA-N domain family protein 2161744..2162559 Escherichia coli O104:H4 str. 2011C-3493 13699603 YP_006778772.1 CDS O3K_10385 NC_018658.1 2162561 2163556 D hypothetical protein 2162561..2163556 Escherichia coli O104:H4 str. 2011C-3493 13699604 YP_006778773.1 CDS O3K_10390 NC_018658.1 2163574 2163915 D antitermination protein from phage origin 2163574..2163915 Escherichia coli O104:H4 str. 2011C-3493 13699605 YP_006778774.1 CDS O3K_10395 NC_018658.1 2163928 2164476 R hypothetical protein complement(2163928..2164476) Escherichia coli O104:H4 str. 2011C-3493 13699606 YP_006778775.1 CDS O3K_10400 NC_018658.1 2164463 2165389 R hypothetical protein complement(2164463..2165389) Escherichia coli O104:H4 str. 2011C-3493 13699607 YP_006778776.1 CDS O3K_10405 NC_018658.1 2165654 2165857 D hypothetical protein 2165654..2165857 Escherichia coli O104:H4 str. 2011C-3493 13699608 YP_006778777.1 CDS O3K_10410 NC_018658.1 2166009 2167058 D COG0863 DNA modification methylase; DNA adenine methyltransferase ( DNA methylase) from phage origin 2166009..2167058 Escherichia coli O104:H4 str. 2011C-3493 13699609 YP_006778778.1 CDS O3K_10415 NC_018658.1 2167850 2169703 D hypothetical protein 2167850..2169703 Escherichia coli O104:H4 str. 2011C-3493 13699613 YP_006778779.1 CDS O3K_10420 NC_018658.1 2169854 2170069 D lysis protein S of prophage CP-933V 2169854..2170069 Escherichia coli O104:H4 str. 2011C-3493 13699614 YP_006778780.1 CDS O3K_10425 NC_018658.1 2170074 2170880 D phage protein 2170074..2170880 Escherichia coli O104:H4 str. 2011C-3493 13699615 YP_006778781.1 CDS O3K_10430 NC_018658.1 2170890 2171204 R hypothetical protein complement(2170890..2171204) Escherichia coli O104:H4 str. 2011C-3493 13699616 YP_006778782.1 CDS O3K_10435 NC_018658.1 2171333 2171866 D COG3772 Phage-related lysozyme (muraminidase); membrane-associated lysozyme, Qin prophage 2171333..2171866 Escherichia coli O104:H4 str. 2011C-3493 13699617 YP_006778783.1 CDS O3K_10440 NC_018658.1 2172023 2172205 D hypothetical protein 2172023..2172205 Escherichia coli O104:H4 str. 2011C-3493 13699618 YP_006778784.1 CDS O3K_10445 NC_018658.1 2172220 2172351 D hypothetical protein 2172220..2172351 Escherichia coli O104:H4 str. 2011C-3493 13699619 YP_006778785.1 CDS O3K_10450 NC_018658.1 2172363 2172821 D Endopeptidase from bacteriophage origin 2172363..2172821 Escherichia coli O104:H4 str. 2011C-3493 13699620 YP_006778786.1 CDS O3K_10455 NC_018658.1 2173172 2173312 D hypothetical protein 2173172..2173312 Escherichia coli O104:H4 str. 2011C-3493 13699621 YP_006778787.1 CDS O3K_10460 NC_018658.1 2173445 2173630 R hypothetical protein complement(2173445..2173630) Escherichia coli O104:H4 str. 2011C-3493 13699622 YP_006778788.1 CDS O3K_10465 NC_018658.1 2173646 2173801 R hypothetical protein complement(2173646..2173801) Escherichia coli O104:H4 str. 2011C-3493 13699623 YP_006778789.1 CDS O3K_10470 NC_018658.1 2174025 2174573 D COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; prophage Qin DNA packaging protein NU1-like protein 2174025..2174573 Escherichia coli O104:H4 str. 2011C-3493 13699624 YP_006778790.1 CDS O3K_10475 NC_018658.1 2174545 2176473 D COG5525 Bacteriophage tail assembly protein; DNA packaging protein of prophage 2174545..2176473 Escherichia coli O104:H4 str. 2011C-3493 13699625 YP_006778791.1 CDS O3K_10480 NC_018658.1 2176457 2176663 D head completion protein 2176457..2176663 Escherichia coli O104:H4 str. 2011C-3493 13699626 YP_006778792.1 CDS O3K_10485 NC_018658.1 2176660 2178252 D COG5511 Bacteriophage capsid protein; head protein Gp4 2176660..2178252 Escherichia coli O104:H4 str. 2011C-3493 13699627 YP_006778793.1 CDS O3K_10490 NC_018658.1 2178242 2179747 D COG0616 Periplasmic serine proteases (ClpP class); Head-tail preconnector protein GP5 (Contains: Scaffold protein GP6 (Head protein GP6)) 2178242..2179747 Escherichia coli O104:H4 str. 2011C-3493 13699628 YP_006778794.1 CDS O3K_10495 NC_018658.1 2179784 2180131 D putative head-DNA stabilization protein 2179784..2180131 Escherichia coli O104:H4 str. 2011C-3493 13699629 YP_006778795.1 CDS O3K_10500 NC_018658.1 2180189 2181217 D Major head protein (Head protein gp7) 2180189..2181217 Escherichia coli O104:H4 str. 2011C-3493 13699630 YP_006778796.1 CDS O3K_10505 NC_018658.1 2181269 2181652 D putative DNA packaging protein 2181269..2181652 Escherichia coli O104:H4 str. 2011C-3493 13699631 YP_006778797.1 CDS O3K_10510 NC_018658.1 2181645 2181998 D Tail attachment protein (Minor capsid protein FII) 2181645..2181998 Escherichia coli O104:H4 str. 2011C-3493 13699632 YP_006778798.1 CDS O3K_10515 NC_018658.1 2182013 2182588 D minor tail protein Z (GpZ) 2182013..2182588 Escherichia coli O104:H4 str. 2011C-3493 13699633 YP_006778799.1 CDS O3K_10520 NC_018658.1 2182585 2182980 D putative minor tail protein 2182585..2182980 Escherichia coli O104:H4 str. 2011C-3493 13699634 YP_006778800.1 CDS O3K_10525 NC_018658.1 2182988 2183740 D COG5492 Bacterial surface proteins containing Ig-like domains; Major tail protein V 2182988..2183740 Escherichia coli O104:H4 str. 2011C-3493 13699635 YP_006778801.1 CDS O3K_10530 NC_018658.1 2183754 2184176 D putative minor tail protein 2183754..2184176 Escherichia coli O104:H4 str. 2011C-3493 13699636 YP_006778802.1 CDS O3K_10535 NC_018658.1 2184203 2184616 D putative minor tail protein 2184203..2184616 Escherichia coli O104:H4 str. 2011C-3493 13699637 YP_006778803.1 CDS O3K_10540 NC_018658.1 2184597 2187209 D COG5281 Phage-related minor tail protein; tail length tape measure protein 2184597..2187209 Escherichia coli O104:H4 str. 2011C-3493 13699638 YP_006778804.1 CDS O3K_10545 NC_018658.1 2187206 2187535 D COG4718 Phage-related protein; minor tail protein M 2187206..2187535 Escherichia coli O104:H4 str. 2011C-3493 13699639 YP_006778805.1 CDS O3K_10550 NC_018658.1 2187535 2188233 D COG4672 Phage-related protein; Minor tail protein L 2187535..2188233 Escherichia coli O104:H4 str. 2011C-3493 13699640 YP_006778806.1 CDS O3K_10555 NC_018658.1 2188238 2188981 D COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; tail fiber component K of prophage 2188238..2188981 Escherichia coli O104:H4 str. 2011C-3493 13699641 YP_006778807.1 CDS O3K_10560 NC_018658.1 2188879 2189550 D COG4723 Phage-related protein, tail component; tail assembly protein I 2188879..2189550 Escherichia coli O104:H4 str. 2011C-3493 13699642 YP_006778808.1 CDS O3K_10565 NC_018658.1 2189611 2193006 D COG4733 Phage-related protein, tail component; Host specificity protein J 2189611..2193006 Escherichia coli O104:H4 str. 2011C-3493 13699643 YP_006778809.1 CDS O3K_10570 NC_018658.1 2193074 2193673 D putative outer membrane Lom 2193074..2193673 Escherichia coli O104:H4 str. 2011C-3493 13699644 YP_006778810.1 CDS O3K_10575 NC_018658.1 2193825 2195363 D tail fiber protein (modular protein) 2193825..2195363 Escherichia coli O104:H4 str. 2011C-3493 13699645 YP_006778811.1 CDS O3K_10580 NC_018658.1 2195372 2195980 D hypothetical protein 2195372..2195980 Escherichia coli O104:H4 str. 2011C-3493 13699646 YP_006778812.1 CDS O3K_10585 NC_018658.1 2196519 2196767 R DNA-damage-inducible protein complement(2196519..2196767) Escherichia coli O104:H4 str. 2011C-3493 13699647 YP_006778813.1 CDS O3K_10590 NC_018658.1 2196864 2197040 D hypothetical protein 2196864..2197040 Escherichia coli O104:H4 str. 2011C-3493 13699648 YP_006778814.1 CDS O3K_10595 NC_018658.1 2197122 2197688 R COG1335 Amidases related to nicotinamidase; hydrolase complement(2197122..2197688) Escherichia coli O104:H4 str. 2011C-3493 13699649 YP_006778815.1 CDS aspS NC_018658.1 2197998 2199770 D COG0173 Aspartyl-tRNA synthetase; aspartyl-tRNA synthetase 2197998..2199770 Escherichia coli O104:H4 str. 2011C-3493 13699650 YP_006778816.1 CDS nudB NC_018658.1 2199772 2200215 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; dihydroneopterin triphosphate pyrophosphatase 2199772..2200215 Escherichia coli O104:H4 str. 2011C-3493 13699651 YP_006778817.1 CDS O3K_10610 NC_018658.1 2200244 2200984 D COG0217 Uncharacterized conserved protein; hypothetical protein 2200244..2200984 Escherichia coli O104:H4 str. 2011C-3493 13699652 YP_006778818.1 CDS ruvC NC_018658.1 2201019 2201540 D COG0817 Holliday junction resolvasome, endonuclease subunit; Holliday junction resolvase 2201019..2201540 Escherichia coli O104:H4 str. 2011C-3493 13699653 YP_006778819.1 CDS O3K_10620 NC_018658.1 2201542 2202144 R hypothetical protein complement(2201542..2202144) Escherichia coli O104:H4 str. 2011C-3493 13699654 YP_006778820.1 CDS ruvA NC_018658.1 2202419 2203030 D COG0632 Holliday junction resolvasome, DNA-binding subunit; Holliday junction DNA helicase RuvA 2202419..2203030 Escherichia coli O104:H4 str. 2011C-3493 13699655 YP_006778821.1 CDS ruvB NC_018658.1 2203039 2204049 D COG2255 Holliday junction resolvasome, helicase subunit; Holliday junction DNA helicase RuvB 2203039..2204049 Escherichia coli O104:H4 str. 2011C-3493 13699656 YP_006778822.1 CDS znuB NC_018658.1 2204196 2204981 R COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; high-affinity zinc transporter membrane protein complement(2204196..2204981) Escherichia coli O104:H4 str. 2011C-3493 13699657 YP_006778823.1 CDS znuC NC_018658.1 2204978 2205733 R COG1121 ABC-type Mn/Zn transport systems, ATPase component; high-affinity zinc transporter ATPase complement(2204978..2205733) Escherichia coli O104:H4 str. 2011C-3493 13699658 YP_006778824.1 CDS znuA NC_018658.1 2205812 2206744 D COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin; high-affinity zinc transporter periplasmic protein 2205812..2206744 Escherichia coli O104:H4 str. 2011C-3493 13699659 YP_006778825.1 CDS O3K_10650 NC_018658.1 2206760 2208082 D COG0739 Membrane proteins related to metalloendopeptidases; peptidase 2206760..2208082 Escherichia coli O104:H4 str. 2011C-3493 13699660 YP_006778826.1 CDS O3K_10655 NC_018658.1 2208202 2209173 D COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2208202..2209173 Escherichia coli O104:H4 str. 2011C-3493 13699661 YP_006778827.1 CDS O3K_10660 NC_018658.1 2209304 2210746 R COG0469 Pyruvate kinase; pyruvate kinase complement(2209304..2210746) Escherichia coli O104:H4 str. 2011C-3493 13699662 YP_006778828.1 CDS O3K_10665 NC_018658.1 2210874 2211743 R COG1737 Transcriptional regulators; DNA-binding transcriptional regulator HexR complement(2210874..2211743) Escherichia coli O104:H4 str. 2011C-3493 13699663 YP_006778829.1 CDS O3K_10670 NC_018658.1 2211766 2211915 D hypothetical protein 2211766..2211915 Escherichia coli O104:H4 str. 2011C-3493 13699664 YP_006778830.1 CDS O3K_10675 NC_018658.1 2212081 2213556 D COG0364 Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 2212081..2213556 Escherichia coli O104:H4 str. 2011C-3493 13699665 YP_006778831.1 CDS O3K_10680 NC_018658.1 2213791 2215602 D COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; phosphogluconate dehydratase 2213791..2215602 Escherichia coli O104:H4 str. 2011C-3493 13699666 YP_006778832.1 CDS O3K_10685 NC_018658.1 2215639 2216280 D COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2215639..2216280 Escherichia coli O104:H4 str. 2011C-3493 13699667 YP_006778833.1 CDS purT NC_018658.1 2216336 2217514 R COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase); phosphoribosylglycinamide formyltransferase 2 complement(2216336..2217514) Escherichia coli O104:H4 str. 2011C-3493 13699668 YP_006778834.1 CDS O3K_10695 NC_018658.1 2217648 2217938 D COG3141 Uncharacterized protein conserved in bacteria; DNA damage-inducible protein YebG 2217648..2217938 Escherichia coli O104:H4 str. 2011C-3493 13699669 YP_006778835.1 CDS O3K_10700 NC_018658.1 2218005 2218361 D hypothetical protein 2218005..2218361 Escherichia coli O104:H4 str. 2011C-3493 13699670 YP_006778836.1 CDS O3K_10705 NC_018658.1 2218518 2218628 R hypothetical protein complement(2218518..2218628) Escherichia coli O104:H4 str. 2011C-3493 13699671 YP_006778837.1 CDS O3K_10710 NC_018658.1 2218688 2219347 D COG2979 Uncharacterized protein conserved in bacteria; hypothetical protein 2218688..2219347 Escherichia coli O104:H4 str. 2011C-3493 13699672 YP_006778838.1 CDS O3K_10715 NC_018658.1 2219556 2221616 D COG1770 Protease II; protease 2 2219556..2221616 Escherichia coli O104:H4 str. 2011C-3493 13699673 YP_006778839.1 CDS O3K_10720 NC_018658.1 2221613 2222275 R COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; exodeoxyribonuclease X complement(2221613..2222275) Escherichia coli O104:H4 str. 2011C-3493 13699674 YP_006778840.1 CDS O3K_10725 NC_018658.1 2222299 2222955 R COG0388 Predicted amidohydrolase; carbon-nitrogen family hydrolase complement(2222299..2222955) Escherichia coli O104:H4 str. 2011C-3493 13699675 YP_006778841.1 CDS O3K_10730 NC_018658.1 2223057 2223287 R DNA polymerase III subunit theta complement(2223057..2223287) Escherichia coli O104:H4 str. 2011C-3493 13699676 YP_006778842.1 CDS O3K_10735 NC_018658.1 2223426 2223800 D COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; hypothetical protein 2223426..2223800 Escherichia coli O104:H4 str. 2011C-3493 13699677 YP_006778843.1 CDS O3K_10740 NC_018658.1 2223804 2224676 D COG1276 Putative copper export protein; copper resistance protein D 2223804..2224676 Escherichia coli O104:H4 str. 2011C-3493 13699678 YP_006778844.1 CDS O3K_10745 NC_018658.1 2224689 2225030 D hypothetical protein 2224689..2225030 Escherichia coli O104:H4 str. 2011C-3493 13699679 YP_006778845.1 CDS O3K_10750 NC_018658.1 2225115 2225201 D hypothetical protein 2225115..2225201 Escherichia coli O104:H4 str. 2011C-3493 13699680 YP_006778846.1 CDS pphA NC_018658.1 2225426 2226082 D COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; serine/threonine protein phosphatase 1 2225426..2226082 Escherichia coli O104:H4 str. 2011C-3493 13699681 YP_006778847.1 CDS O3K_10760 NC_018658.1 2226083 2226274 R hypothetical protein complement(2226083..2226274) Escherichia coli O104:H4 str. 2011C-3493 13699682 YP_006778848.1 CDS O3K_10765 NC_018658.1 2226379 2226615 R hypothetical protein complement(2226379..2226615) Escherichia coli O104:H4 str. 2011C-3493 13699683 YP_006778849.1 CDS yebU NC_018658.1 2226733 2228172 R COG0144 tRNA and rRNA cytosine-C5-methylases; rRNA (cytosine-C(5)-)-methyltransferase RsmF complement(2226733..2228172) Escherichia coli O104:H4 str. 2011C-3493 13699684 YP_006778850.1 CDS O3K_10775 NC_018658.1 2228252 2230885 R COG3008 Paraquat-inducible protein B; mce-like protein complement(2228252..2230885) Escherichia coli O104:H4 str. 2011C-3493 13699685 YP_006778851.1 CDS O3K_10780 NC_018658.1 2230854 2232137 R COG2995 Uncharacterized paraquat-inducible protein A; hypothetical protein complement(2230854..2232137) Escherichia coli O104:H4 str. 2011C-3493 13699686 YP_006778852.1 CDS O3K_10785 NC_018658.1 2232267 2232764 D COG1956 GAF domain-containing protein; hypothetical protein 2232267..2232764 Escherichia coli O104:H4 str. 2011C-3493 13699687 YP_006778853.1 CDS O3K_10790 NC_018658.1 2232861 2233559 D COG3109 Activator of osmoprotectant transporter ProP; ProP expression regulator 2232861..2233559 Escherichia coli O104:H4 str. 2011C-3493 13699688 YP_006778854.1 CDS O3K_10795 NC_018658.1 2233579 2235627 D COG0793 Periplasmic protease; carboxy-terminal protease 2233579..2235627 Escherichia coli O104:H4 str. 2011C-3493 13699689 YP_006778855.1 CDS O3K_10800 NC_018658.1 2235819 2236700 D COG0501 Zn-dependent protease with chaperone function; heat shock protein HtpX 2235819..2236700 Escherichia coli O104:H4 str. 2011C-3493 13699690 YP_006778856.1 CDS O3K_10805 NC_018658.1 2236746 2238119 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2236746..2238119) Escherichia coli O104:H4 str. 2011C-3493 13699691 YP_006778857.1 CDS O3K_10810 NC_018658.1 2238296 2239087 D COG1414 Transcriptional regulator; DNA-binding transcriptional regulator KdgR 2238296..2239087 Escherichia coli O104:H4 str. 2011C-3493 13699692 YP_006778858.1 CDS O3K_10815 NC_018658.1 2239230 2239469 R hypothetical protein complement(2239230..2239469) Escherichia coli O104:H4 str. 2011C-3493 13699693 YP_006778859.1 CDS O3K_10820 NC_018658.1 2239628 2239771 D PhoPQ regulatory protein 2239628..2239771 Escherichia coli O104:H4 str. 2011C-3493 13699694 YP_006778860.1 CDS O3K_10825 NC_018658.1 2239846 2240133 D hypothetical protein 2239846..2240133 Escherichia coli O104:H4 str. 2011C-3493 13699695 YP_006778861.1 CDS O3K_10830 NC_018658.1 2240803 2240946 D hypothetical protein 2240803..2240946 Escherichia coli O104:H4 str. 2011C-3493 13699696 YP_006778862.1 CDS O3K_10835 NC_018658.1 2240959 2241168 D COG1278 Cold shock proteins; cold-shock protein 2240959..2241168 Escherichia coli O104:H4 str. 2011C-3493 13699697 YP_006778863.1 CDS rrmA NC_018658.1 2241334 2242143 D COG0500 SAM-dependent methyltransferases; 23S rRNA methyltransferase A 2241334..2242143 Escherichia coli O104:H4 str. 2011C-3493 13699698 YP_006778864.1 CDS O3K_10845 NC_018658.1 2242140 2242706 R COG1971 Predicted membrane protein; hypothetical protein complement(2242140..2242706) Escherichia coli O104:H4 str. 2011C-3493 13699699 YP_006778865.1 CDS O3K_10850 NC_018658.1 2243135 2243593 R COG4811 Predicted membrane protein; hypothetical protein complement(2243135..2243593) Escherichia coli O104:H4 str. 2011C-3493 13699700 YP_006778866.1 CDS O3K_10855 NC_018658.1 2243648 2244508 R COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose-specific transporter subunit IID complement(2243648..2244508) Escherichia coli O104:H4 str. 2011C-3493 13699701 YP_006778867.1 CDS O3K_10860 NC_018658.1 2244512 2245312 R COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose-specific transporter subunit IIC complement(2244512..2245312) Escherichia coli O104:H4 str. 2011C-3493 13699702 YP_006778868.1 CDS O3K_10865 NC_018658.1 2245375 2246346 R COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose-specific transporter subunit IIAB complement(2245375..2246346) Escherichia coli O104:H4 str. 2011C-3493 13699703 YP_006778869.1 CDS O3K_10870 NC_018658.1 2246809 2248365 D COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 2246809..2248365 Escherichia coli O104:H4 str. 2011C-3493 13699704 YP_006778870.1 CDS O3K_10875 NC_018658.1 2248369 2249967 R COG2200 FOG: EAL domain; phosphodiesterase complement(2248369..2249967) Escherichia coli O104:H4 str. 2011C-3493 13699705 YP_006778871.1 CDS O3K_10880 NC_018658.1 2250098 2251462 R COG1760 L-serine deaminase; L-serine deaminase complement(2250098..2251462) Escherichia coli O104:H4 str. 2011C-3493 13699706 YP_006778872.1 CDS O3K_10885 NC_018658.1 2251646 2252224 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase complement(2251646..2252224) Escherichia coli O104:H4 str. 2011C-3493 13699707 YP_006778873.1 CDS pabB NC_018658.1 2252228 2253589 R COG0147 Anthranilate/para-aminobenzoate synthases component I; aminodeoxychorismate synthase subunit I complement(2252228..2253589) Escherichia coli O104:H4 str. 2011C-3493 13699708 YP_006778874.1 CDS O3K_10895 NC_018658.1 2253663 2253842 D COG3140 Uncharacterized protein conserved in bacteria; hypothetical protein 2253663..2253842 Escherichia coli O104:H4 str. 2011C-3493 13699709 YP_006778875.1 CDS O3K_10900 NC_018658.1 2253962 2254321 R hypothetical protein complement(2253962..2254321) Escherichia coli O104:H4 str. 2011C-3493 13699710 YP_006778876.1 CDS O3K_10905 NC_018658.1 2254684 2255028 R COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein complement(2254684..2255028) Escherichia coli O104:H4 str. 2011C-3493 13699711 YP_006778877.1 CDS O3K_10910 NC_018658.1 2255160 2257070 D COG1199 Rad3-related DNA helicases; Helicase c2 2255160..2257070 Escherichia coli O104:H4 str. 2011C-3493 13699712 YP_006778878.1 CDS O3K_10915 NC_018658.1 2257128 2257823 D COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; peptidase 2257128..2257823 Escherichia coli O104:H4 str. 2011C-3493 13699713 YP_006778879.1 CDS O3K_10920 NC_018658.1 2257863 2258444 D COG3065 Starvation-inducible outer membrane lipoprotein; outer membrane lipoprotein 2257863..2258444 Escherichia coli O104:H4 str. 2011C-3493 13699714 YP_006778880.1 CDS O3K_10925 NC_018658.1 2258649 2260334 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; long-chain-fatty-acid--CoA ligase 2258649..2260334 Escherichia coli O104:H4 str. 2011C-3493 13699715 YP_006778881.1 CDS O3K_10930 NC_018658.1 2260404 2261531 D COG0349 Ribonuclease D; ribonuclease D 2260404..2261531 Escherichia coli O104:H4 str. 2011C-3493 13699716 YP_006778882.1 CDS O3K_10935 NC_018658.1 2261585 2262550 R COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; oxidoreductase complement(2261585..2262550) Escherichia coli O104:H4 str. 2011C-3493 13699717 YP_006778883.1 CDS O3K_10940 NC_018658.1 2262606 2263730 R COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; dioxygenase subunit alpha yeaW complement(2262606..2263730) Escherichia coli O104:H4 str. 2011C-3493 13699718 YP_006778884.1 CDS O3K_10945 NC_018658.1 2263762 2265372 R COG1292 Choline-glycine betaine transporter; transporter complement(2263762..2265372) Escherichia coli O104:H4 str. 2011C-3493 13699719 YP_006778885.1 CDS O3K_10950 NC_018658.1 2265623 2266708 R COG0473 Isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase complement(2265623..2266708) Escherichia coli O104:H4 str. 2011C-3493 13699720 YP_006778886.1 CDS O3K_10955 NC_018658.1 2266811 2267734 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 2266811..2267734 Escherichia coli O104:H4 str. 2011C-3493 13699721 YP_006778887.1 CDS O3K_10960 NC_018658.1 2267861 2268499 D COG1280 Putative threonine efflux protein; leucine export protein LeuE 2267861..2268499 Escherichia coli O104:H4 str. 2011C-3493 13699722 YP_006778888.1 CDS O3K_10965 NC_018658.1 2268672 2269031 D COG3615 Uncharacterized protein/domain, possibly involved in tellurite resistance; hypothetical protein 2268672..2269031 Escherichia coli O104:H4 str. 2011C-3493 13699723 YP_006778889.1 CDS O3K_10970 NC_018658.1 2269035 2269223 D hypothetical protein 2269035..2269223 Escherichia coli O104:H4 str. 2011C-3493 13699724 YP_006778890.1 CDS O3K_10975 NC_018658.1 2269678 2270886 D COG0675 Transposase and inactivated derivatives; transposase 2269678..2270886 Escherichia coli O104:H4 str. 2011C-3493 13699725 YP_006778891.1 CDS O3K_10980 NC_018658.1 2271113 2271361 D COG2261 Predicted membrane protein; hypothetical protein 2271113..2271361 Escherichia coli O104:H4 str. 2011C-3493 13699726 YP_006778892.1 CDS O3K_10985 NC_018658.1 2271420 2271494 R hypothetical protein complement(2271420..2271494) Escherichia coli O104:H4 str. 2011C-3493 13699727 YP_006778893.1 CDS O3K_10990 NC_018658.1 2271628 2272653 R COG2199 FOG: GGDEF domain; diguanylate cyclase complement(2271628..2272653) Escherichia coli O104:H4 str. 2011C-3493 13699728 YP_006778894.1 CDS O3K_10995 NC_018658.1 2272836 2273090 D COG3042 Putative hemolysin; lipoprotein 2272836..2273090 Escherichia coli O104:H4 str. 2011C-3493 13699729 YP_006778895.1 CDS O3K_11000 NC_018658.1 2273112 2273459 R COG3189 Uncharacterized conserved protein; hypothetical protein complement(2273112..2273459) Escherichia coli O104:H4 str. 2011C-3493 13699730 YP_006778896.1 CDS O3K_11005 NC_018658.1 2273514 2274695 R COG2807 Cyanate permease; transporter complement(2273514..2274695) Escherichia coli O104:H4 str. 2011C-3493 13699731 YP_006778897.1 CDS O3K_11010 NC_018658.1 2274792 2275613 D COG2207 AraC-type DNA-binding domain-containing proteins; putative DNA-binding transcriptional regulator, ARAC-type 2274792..2275613 Escherichia coli O104:H4 str. 2011C-3493 13699732 YP_006778898.1 CDS O3K_11015 NC_018658.1 2275478 2276020 R COG2707 Predicted membrane protein; inner membrane protein complement(2275478..2276020) Escherichia coli O104:H4 str. 2011C-3493 13699733 YP_006778899.1 CDS O3K_11020 NC_018658.1 2276142 2276294 D hypothetical protein 2276142..2276294 Escherichia coli O104:H4 str. 2011C-3493 13699734 YP_006778900.1 CDS O3K_11025 NC_018658.1 2276295 2276798 R COG2606 Uncharacterized conserved protein; hypothetical protein complement(2276295..2276798) Escherichia coli O104:H4 str. 2011C-3493 13699735 YP_006778901.1 CDS O3K_11030 NC_018658.1 2276841 2278331 R COG2199 FOG: GGDEF domain; diguanylate cyclase complement(2276841..2278331) Escherichia coli O104:H4 str. 2011C-3493 13699736 YP_006778902.1 CDS O3K_11035 NC_018658.1 2278512 2279987 R COG2199 FOG: GGDEF domain; hypothetical protein complement(2278512..2279987) Escherichia coli O104:H4 str. 2011C-3493 13699737 YP_006778903.1 CDS O3K_11040 NC_018658.1 2280134 2281417 R COG2718 Uncharacterized conserved protein; hypothetical protein complement(2280134..2281417) Escherichia coli O104:H4 str. 2011C-3493 13699738 YP_006778904.1 CDS O3K_11045 NC_018658.1 2281530 2283464 R COG2766 Putative Ser protein kinase; PrkA family serine protein kinase complement(2281530..2283464) Escherichia coli O104:H4 str. 2011C-3493 13699739 YP_006778905.1 CDS O3K_11050 NC_018658.1 2283900 2284646 D COG3713 Outer membrane protein V; MltA-interacting protein 2283900..2284646 Escherichia coli O104:H4 str. 2011C-3493 13699740 YP_006778906.1 CDS O3K_11055 NC_018658.1 2284736 2285590 D COG0656 Aldo/keto reductases, related to diketogulonate reductase; oxidoreductase 2284736..2285590 Escherichia coli O104:H4 str. 2011C-3493 13699741 YP_006778907.1 CDS O3K_11060 NC_018658.1 2285641 2286525 R COG0676 Uncharacterized enzymes related to aldose 1-epimerase; aldose 1-epimerase complement(2285641..2286525) Escherichia coli O104:H4 str. 2011C-3493 13699742 YP_006778908.1 CDS gapA NC_018658.1 2286609 2287604 R COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase complement(2286609..2287604) Escherichia coli O104:H4 str. 2011C-3493 13699743 YP_006778909.1 CDS O3K_11070 NC_018658.1 2287946 2288359 D COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; methionine sulfoxide reductase B 2287946..2288359 Escherichia coli O104:H4 str. 2011C-3493 13699744 YP_006778910.1 CDS O3K_11075 NC_018658.1 2288401 2288673 D COG3139 Uncharacterized protein conserved in bacteria; hypothetical protein 2288401..2288673 Escherichia coli O104:H4 str. 2011C-3493 13699745 YP_006778911.1 CDS O3K_11080 NC_018658.1 2289043 2290119 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase zinc-binding dehydrogenase family protein 2289043..2290119 Escherichia coli O104:H4 str. 2011C-3493 13699746 YP_006778912.1 CDS O3K_11085 NC_018658.1 2290146 2291525 D COG0477 Permeases of the major facilitator superfamily; transporter, MFS superfamily protein 2290146..2291525 Escherichia coli O104:H4 str. 2011C-3493 13699747 YP_006778913.1 CDS O3K_11090 NC_018658.1 2291542 2292585 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; putative iditol dehydrogenase 2291542..2292585 Escherichia coli O104:H4 str. 2011C-3493 13699748 YP_006778914.1 CDS O3K_11095 NC_018658.1 2292606 2293442 D COG0191 Fructose/tagatose bisphosphate aldolase; putative aldolase 2292606..2293442 Escherichia coli O104:H4 str. 2011C-3493 13699749 YP_006778915.1 CDS O3K_11100 NC_018658.1 2293447 2294394 D COG0524 Sugar kinases, ribokinase family; putative kinase 2293447..2294394 Escherichia coli O104:H4 str. 2011C-3493 13699750 YP_006778916.1 CDS O3K_11105 NC_018658.1 2294404 2295384 D COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 2294404..2295384 Escherichia coli O104:H4 str. 2011C-3493 13699751 YP_006778917.1 CDS O3K_11110 NC_018658.1 2295521 2296279 D COG1349 Transcriptional regulators of sugar metabolism; putative DEOR-type transcriptional regulator 2295521..2296279 Escherichia coli O104:H4 str. 2011C-3493 13699752 YP_006778918.1 CDS O3K_11115 NC_018658.1 2296396 2297754 D COG0477 Permeases of the major facilitator superfamily; transporter, MFS superfamily protein 2296396..2297754 Escherichia coli O104:H4 str. 2011C-3493 13699753 YP_006778919.1 CDS O3K_11120 NC_018658.1 2297847 2298488 R COG1335 Amidases related to nicotinamidase; nicotinamidase/pyrazinamidase complement(2297847..2298488) Escherichia coli O104:H4 str. 2011C-3493 13699754 YP_006778920.1 CDS ansA NC_018658.1 2298499 2299515 R COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; asparaginase complement(2298499..2299515) Escherichia coli O104:H4 str. 2011C-3493 13699755 YP_006778921.1 CDS O3K_11130 NC_018658.1 2299682 2301538 R COG0616 Periplasmic serine proteases (ClpP class); protease 4 complement(2299682..2301538) Escherichia coli O104:H4 str. 2011C-3493 13699756 YP_006778922.1 CDS O3K_11135 NC_018658.1 2301699 2302250 D COG0778 Nitroreductase; oxidoreductase 2301699..2302250 Escherichia coli O104:H4 str. 2011C-3493 13699757 YP_006778923.1 CDS O3K_11140 NC_018658.1 2302367 2303410 D COG0709 Selenophosphate synthase; selenophosphate synthetase 2302367..2303410 Escherichia coli O104:H4 str. 2011C-3493 13699758 YP_006778924.1 CDS O3K_11145 NC_018658.1 2303415 2305376 D COG0550 Topoisomerase IA; DNA topoisomerase III 2303415..2305376 Escherichia coli O104:H4 str. 2011C-3493 13699759 YP_006778925.1 CDS O3K_11150 NC_018658.1 2305504 2306544 D hypothetical protein 2305504..2306544 Escherichia coli O104:H4 str. 2011C-3493 13699760 YP_006778926.1 CDS O3K_11155 NC_018658.1 2306661 2308004 R COG0334 Glutamate dehydrogenase/leucine dehydrogenase; glutamate dehydrogenase complement(2306661..2308004) Escherichia coli O104:H4 str. 2011C-3493 13699761 YP_006778927.1 CDS O3K_11160 NC_018658.1 2308240 2308512 D hypothetical protein 2308240..2308512 Escherichia coli O104:H4 str. 2011C-3493 13699762 YP_006778928.1 CDS O3K_11165 NC_018658.1 2308478 2308885 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase complement(2308478..2308885) Escherichia coli O104:H4 str. 2011C-3493 13699763 YP_006778929.1 CDS O3K_11170 NC_018658.1 2308972 2309592 D COG0558 Phosphatidylglycerophosphate synthase; putative phosphatidyl transferase, inner membrane protein 2308972..2309592 Escherichia coli O104:H4 str. 2011C-3493 13699764 YP_006778930.1 CDS O3K_11175 NC_018658.1 2309601 2310908 R COG2897 Rhodanese-related sulfurtransferase; thiosulfate sulfur transferase / thiosulfate binding protein complement(2309601..2310908) Escherichia coli O104:H4 str. 2011C-3493 13699765 YP_006778931.1 CDS O3K_11180 NC_018658.1 2310975 2311628 R COG4136 ABC-type uncharacterized transport system, ATPase component; putative transporter subunit complement(2310975..2311628) Escherichia coli O104:H4 str. 2011C-3493 13699766 YP_006778932.1 CDS O3K_11185 NC_018658.1 2311628 2313163 R COG4135 ABC-type uncharacterized transport system, permease component; ABC transporter membrane protein complement(2311628..2313163) Escherichia coli O104:H4 str. 2011C-3493 13699767 YP_006778933.1 CDS O3K_11190 NC_018658.1 2313136 2314302 R COG4134 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein complement(2313136..2314302) Escherichia coli O104:H4 str. 2011C-3493 13699768 YP_006778934.1 CDS O3K_11195 NC_018658.1 2314312 2314860 R COG2128 Uncharacterized conserved protein; carboxymuconolactone decarboxylase family protein complement(2314312..2314860) Escherichia coli O104:H4 str. 2011C-3493 13699769 YP_006778935.1 CDS O3K_11200 NC_018658.1 2314860 2315567 R COG0398 Uncharacterized conserved protein; inner membrane protein complement(2314860..2315567) Escherichia coli O104:H4 str. 2011C-3493 13699770 YP_006778936.1 CDS O3K_11205 NC_018658.1 2315581 2316258 R hypothetical protein complement(2315581..2316258) Escherichia coli O104:H4 str. 2011C-3493 13699771 YP_006778937.1 CDS O3K_11210 NC_018658.1 2316263 2316973 R COG0398 Uncharacterized conserved protein; inner membrane protein complement(2316263..2316973) Escherichia coli O104:H4 str. 2011C-3493 13699772 YP_006778938.1 CDS O3K_11215 NC_018658.1 2317140 2317946 R COG0708 Exonuclease III; exonuclease III complement(2317140..2317946) Escherichia coli O104:H4 str. 2011C-3493 13699773 YP_006778939.1 CDS O3K_11220 NC_018658.1 2318392 2319612 D COG4992 Ornithine/acetylornithine aminotransferase; bifunctional succinylornithine transaminase/acetylornithine transaminase 2318392..2319612 Escherichia coli O104:H4 str. 2011C-3493 13699774 YP_006778940.1 CDS O3K_11225 NC_018658.1 2319609 2320643 D COG3138 Arginine/ornithine N-succinyltransferase beta subunit; arginine succinyltransferase 2319609..2320643 Escherichia coli O104:H4 str. 2011C-3493 13699775 YP_006778941.1 CDS astD NC_018658.1 2320640 2322118 D COG1012 NAD-dependent aldehyde dehydrogenases; succinylglutamic semialdehyde dehydrogenase 2320640..2322118 Escherichia coli O104:H4 str. 2011C-3493 13699776 YP_006778942.1 CDS O3K_11235 NC_018658.1 2322115 2323458 D COG3724 Succinylarginine dihydrolase; succinylarginine dihydrolase 2322115..2323458 Escherichia coli O104:H4 str. 2011C-3493 13699777 YP_006778943.1 CDS O3K_11240 NC_018658.1 2323451 2324419 D COG2988 Succinylglutamate desuccinylase; succinylglutamate desuccinylase 2323451..2324419 Escherichia coli O104:H4 str. 2011C-3493 13699778 YP_006778944.1 CDS O3K_11245 NC_018658.1 2324749 2325234 D COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; hypothetical protein 2324749..2325234 Escherichia coli O104:H4 str. 2011C-3493 13699779 YP_006778945.1 CDS O3K_11250 NC_018658.1 2325437 2326012 D COG3758 Uncharacterized protein conserved in bacteria; hypothetical protein 2325437..2326012 Escherichia coli O104:H4 str. 2011C-3493 13699780 YP_006778946.1 CDS O3K_11255 NC_018658.1 2325972 2326859 R COG0322 Nuclease subunit of the excinuclease complex; nucleotide excision repair endonuclease complement(2325972..2326859) Escherichia coli O104:H4 str. 2011C-3493 13699781 YP_006778947.1 CDS O3K_11260 NC_018658.1 2326929 2327078 D hypothetical protein 2326929..2327078 Escherichia coli O104:H4 str. 2011C-3493 13699782 YP_006778948.1 CDS nadE NC_018658.1 2327089 2327916 R COG0171 NAD synthase; NAD synthetase complement(2327089..2327916) Escherichia coli O104:H4 str. 2011C-3493 13699783 YP_006778949.1 CDS O3K_11270 NC_018658.1 2328118 2328456 D DNA-binding transcriptional activator OsmE 2328118..2328456 Escherichia coli O104:H4 str. 2011C-3493 13701484 YP_006778950.1 CDS O3K_11275 NC_018658.1 2328755 2329075 D COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2328755..2329075 Escherichia coli O104:H4 str. 2011C-3493 13701485 YP_006778951.1 CDS O3K_11280 NC_018658.1 2329160 2330518 D COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2329160..2330518 Escherichia coli O104:H4 str. 2011C-3493 13701486 YP_006778952.1 CDS O3K_11285 NC_018658.1 2330569 2330919 D COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2330569..2330919 Escherichia coli O104:H4 str. 2011C-3493 13701487 YP_006778953.1 CDS O3K_11290 NC_018658.1 2330927 2331769 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator ChbR 2330927..2331769 Escherichia coli O104:H4 str. 2011C-3493 13701488 YP_006778954.1 CDS O3K_11295 NC_018658.1 2331874 2333226 D COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; cryptic phospho-beta-glucosidase, NAD(P)-binding protein 2331874..2333226 Escherichia coli O104:H4 str. 2011C-3493 13701489 YP_006778955.1 CDS O3K_11300 NC_018658.1 2333239 2333997 D COG3394 Uncharacterized protein conserved in bacteria; hypothetical protein 2333239..2333997 Escherichia coli O104:H4 str. 2011C-3493 13701490 YP_006778956.1 CDS katE NC_018658.1 2334044 2336305 R COG0753 Catalase; hydroperoxidase II complement(2334044..2336305) Escherichia coli O104:H4 str. 2011C-3493 13701491 YP_006778957.1 CDS O3K_11310 NC_018658.1 2336509 2336751 D cell division modulator 2336509..2336751 Escherichia coli O104:H4 str. 2011C-3493 13701492 YP_006778958.1 CDS O3K_11325 NC_018658.1 2337800 2338780 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase complement(2337800..2338780) Escherichia coli O104:H4 str. 2011C-3493 13701493 YP_006778959.1 CDS O3K_11330 NC_018658.1 2338779 2339042 D hypothetical protein; ydjO 2338779..2339042 Escherichia coli O104:H4 str. 2011C-3493 13701494 YP_006778960.1 CDS O3K_11335 NC_018658.1 2339046 2340437 R COG1823 Predicted Na+/dicarboxylate symporter; cation-acid symporter complement(2339046..2340437) Escherichia coli O104:H4 str. 2011C-3493 13701495 YP_006778961.1 CDS O3K_11340 NC_018658.1 2340570 2341160 R COG1988 Predicted membrane-bound metal-dependent hydrolases; inner membrane protein complement(2340570..2341160) Escherichia coli O104:H4 str. 2011C-3493 13701496 YP_006778962.1 CDS O3K_11345 NC_018658.1 2341323 2341991 R COG0637 Predicted phosphatase/phosphohexomutase; 2-deoxyglucose-6-phosphatase complement(2341323..2341991) Escherichia coli O104:H4 str. 2011C-3493 13701497 YP_006778963.1 CDS O3K_11350 NC_018658.1 2342138 2342674 D inner membrane protein 2342138..2342674 Escherichia coli O104:H4 str. 2011C-3493 13701498 YP_006778964.1 CDS O3K_11355 NC_018658.1 2342715 2343575 R COG3001 Fructosamine-3-kinase; phosphotransferase/kinase complement(2342715..2343575) Escherichia coli O104:H4 str. 2011C-3493 13701499 YP_006778965.1 CDS O3K_11360 NC_018658.1 2343681 2343971 R hypothetical protein complement(2343681..2343971) Escherichia coli O104:H4 str. 2011C-3493 13701500 YP_006778966.1 CDS O3K_11365 NC_018658.1 2344072 2345001 R COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); 6-phosphofructokinase complement(2344072..2345001) Escherichia coli O104:H4 str. 2011C-3493 13701501 YP_006778967.1 CDS O3K_11370 NC_018658.1 2345288 2346046 D COG3137 Putative salt-induced outer membrane protein; hypothetical protein 2345288..2346046 Escherichia coli O104:H4 str. 2011C-3493 13701502 YP_006778968.1 CDS O3K_11375 NC_018658.1 2346099 2346206 R hypothetical protein complement(2346099..2346206) Escherichia coli O104:H4 str. 2011C-3493 13701503 YP_006778969.1 CDS thrS NC_018658.1 2348804 2350732 D COG0441 Threonyl-tRNA synthetase; threonyl-tRNA synthetase 2348804..2350732 Escherichia coli O104:H4 str. 2011C-3493 13701504 YP_006778970.1 CDS infC NC_018658.1 2350844 2351278 D COG0290 Translation initiation factor 3 (IF-3); translation initiation factor IF-3 2350844..2351278 Escherichia coli O104:H4 str. 2011C-3493 13701505 YP_006778971.1 CDS rpmI NC_018658.1 2351375 2351572 D COG0291 Ribosomal protein L35; 50S ribosomal protein L35 2351375..2351572 Escherichia coli O104:H4 str. 2011C-3493 13701506 YP_006778972.1 CDS rplT NC_018658.1 2351625 2351981 D COG0292 Ribosomal protein L20; 50S ribosomal protein L20 2351625..2351981 Escherichia coli O104:H4 str. 2011C-3493 13701507 YP_006778973.1 CDS pheS NC_018658.1 2352431 2353414 D COG0016 Phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 2352431..2353414 Escherichia coli O104:H4 str. 2011C-3493 13701508 YP_006778974.1 CDS pheT NC_018658.1 2353429 2355816 D COG0073 EMAP domain; phenylalanyl-tRNA synthetase subunit beta 2353429..2355816 Escherichia coli O104:H4 str. 2011C-3493 13701509 YP_006778975.1 CDS ihfA NC_018658.1 2355821 2356120 D COG0776 Bacterial nucleoid DNA-binding protein; integration host factor subunit alpha 2355821..2356120 Escherichia coli O104:H4 str. 2011C-3493 13701510 YP_006778976.1 CDS O3K_11425 NC_018658.1 2356422 2356562 R hypothetical protein complement(2356422..2356562) Escherichia coli O104:H4 str. 2011C-3493 13701511 YP_006778977.1 CDS O3K_11430 NC_018658.1 2356753 2357013 R COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; prophage late promoter activator protein complement(2356753..2357013) Escherichia coli O104:H4 str. 2011C-3493 13701512 YP_006778978.1 CDS O3K_11435 NC_018658.1 2357207 2358187 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase complement(2357207..2358187) Escherichia coli O104:H4 str. 2011C-3493 13701513 YP_006778979.1 CDS O3K_11440 NC_018658.1 2358445 2359614 D hypothetical protein 2358445..2359614 Escherichia coli O104:H4 str. 2011C-3493 13701514 YP_006778980.1 CDS O3K_11445 NC_018658.1 2359706 2360815 R COG3500 Phage protein D; phage protein D complement(2359706..2360815) Escherichia coli O104:H4 str. 2011C-3493 13701515 YP_006778981.1 CDS O3K_11450 NC_018658.1 2360973 2362157 D COG3497 Phage tail sheath protein FI; tail sheath protein 2360973..2362157 Escherichia coli O104:H4 str. 2011C-3493 13701516 YP_006778982.1 CDS O3K_11455 NC_018658.1 2362157 2362669 D COG3498 Phage tail tube protein FII; putative tail tube protein 2362157..2362669 Escherichia coli O104:H4 str. 2011C-3493 13701517 YP_006778983.1 CDS O3K_11460 NC_018658.1 2362724 2363089 D tail protein 2362724..2363089 Escherichia coli O104:H4 str. 2011C-3493 13701518 YP_006778984.1 CDS O3K_11465 NC_018658.1 2363017 2363253 D phage tail protein 2363017..2363253 Escherichia coli O104:H4 str. 2011C-3493 13701519 YP_006778985.1 CDS O3K_11470 NC_018658.1 2363240 2366047 D COG5283 Phage-related tail protein; tail protein (modular protein) 2363240..2366047 Escherichia coli O104:H4 str. 2011C-3493 13701520 YP_006778986.1 CDS O3K_11475 NC_018658.1 2366060 2366548 D COG3499 Phage protein U; tail fiber protein 2366060..2366548 Escherichia coli O104:H4 str. 2011C-3493 13701521 YP_006778987.1 CDS O3K_11480 NC_018658.1 2366705 2367277 D COG1045 Serine acetyltransferase; acetyltransferase 2366705..2367277 Escherichia coli O104:H4 str. 2011C-3493 13701522 YP_006778988.1 CDS O3K_11485 NC_018658.1 2367321 2367899 R putative tail fiber assembly protein complement(2367321..2367899) Escherichia coli O104:H4 str. 2011C-3493 13701523 YP_006778989.1 CDS O3K_11490 NC_018658.1 2367899 2370031 R COG5301 Phage-related tail fibre protein; putative side tail fiber protein complement(2367899..2370031) Escherichia coli O104:H4 str. 2011C-3493 13701524 YP_006778990.1 CDS O3K_11495 NC_018658.1 2370034 2370564 R COG4385 Bacteriophage P2-related tail formation protein; putative phage tail protein complement(2370034..2370564) Escherichia coli O104:H4 str. 2011C-3493 13701525 YP_006778991.1 CDS O3K_11500 NC_018658.1 2370557 2371453 R COG3948 Phage-related baseplate assembly protein; baseplate assembly protein complement(2370557..2371453) Escherichia coli O104:H4 str. 2011C-3493 13701526 YP_006778992.1 CDS O3K_11505 NC_018658.1 2371457 2371807 R COG3628 Phage baseplate assembly protein W; phage baseplate assembly protein complement(2371457..2371807) Escherichia coli O104:H4 str. 2011C-3493 13701527 YP_006778993.1 CDS O3K_11510 NC_018658.1 2371804 2372385 R COG4540 Phage P2 baseplate assembly protein gpV; baseplate assembly protein complement(2371804..2372385) Escherichia coli O104:H4 str. 2011C-3493 13701528 YP_006778994.1 CDS O3K_11515 NC_018658.1 2372382 2373026 R phage tail completion protein S complement(2372382..2373026) Escherichia coli O104:H4 str. 2011C-3493 13701529 YP_006778995.1 CDS O3K_11520 NC_018658.1 2373010 2373477 R Phage tail completion protein R complement(2373010..2373477) Escherichia coli O104:H4 str. 2011C-3493 13701530 YP_006778996.1 CDS O3K_11525 NC_018658.1 2373501 2375381 R hypothetical protein complement(2373501..2375381) Escherichia coli O104:H4 str. 2011C-3493 13701531 YP_006778997.1 CDS O3K_11530 NC_018658.1 2375520 2375927 R COG0164 Ribonuclease HII; hypothetical protein complement(2375520..2375927) Escherichia coli O104:H4 str. 2011C-3493 13701532 YP_006778998.1 CDS O3K_11535 NC_018658.1 2375924 2376316 R endolysin complement(2375924..2376316) Escherichia coli O104:H4 str. 2011C-3493 13701533 YP_006778999.1 CDS O3K_11540 NC_018658.1 2376313 2376636 R putative phage holin complement(2376313..2376636) Escherichia coli O104:H4 str. 2011C-3493 13701534 YP_006779000.1 CDS O3K_11545 NC_018658.1 2376639 2376839 R COG5004 P2-like prophage tail protein X; phage tail protein complement(2376639..2376839) Escherichia coli O104:H4 str. 2011C-3493 13701535 YP_006779001.1 CDS O3K_11550 NC_018658.1 2376839 2377333 R capsid completion protein complement(2376839..2377333) Escherichia coli O104:H4 str. 2011C-3493 13701536 YP_006779002.1 CDS O3K_11555 NC_018658.1 2377435 2378235 R terminase, endonuclease subunit complement(2377435..2378235) Escherichia coli O104:H4 str. 2011C-3493 13701537 YP_006779003.1 CDS O3K_11560 NC_018658.1 2378281 2379333 R major capsid protein complement(2378281..2379333) Escherichia coli O104:H4 str. 2011C-3493 13701538 YP_006779004.1 CDS O3K_11565 NC_018658.1 2379357 2380193 R capsid scaffolding protein complement(2379357..2380193) Escherichia coli O104:H4 str. 2011C-3493 13701539 YP_006779005.1 CDS O3K_11570 NC_018658.1 2380348 2382099 D COG5484 Uncharacterized conserved protein; large subunit terminase 2380348..2382099 Escherichia coli O104:H4 str. 2011C-3493 13701540 YP_006779006.1 CDS O3K_11575 NC_018658.1 2382099 2383145 D COG5518 Bacteriophage capsid portal protein; capsid portal protein 2382099..2383145 Escherichia coli O104:H4 str. 2011C-3493 13701541 YP_006779007.1 CDS O3K_11580 NC_018658.1 2383657 2383920 R hypothetical protein complement(2383657..2383920) Escherichia coli O104:H4 str. 2011C-3493 13701542 YP_006779008.1 CDS O3K_11585 NC_018658.1 2383922 2384353 R hypothetical protein complement(2383922..2384353) Escherichia coli O104:H4 str. 2011C-3493 13701543 YP_006779009.1 CDS O3K_11590 NC_018658.1 2384373 2384687 R plasmid partition protein; modular protein; stability/partitioning protein phage encoded complement(2384373..2384687) Escherichia coli O104:H4 str. 2011C-3493 13701544 YP_006779010.1 CDS O3K_11595 NC_018658.1 2384692 2385651 R COG0443 Molecular chaperone; prophage stability/partitioning protein complement(2384692..2385651) Escherichia coli O104:H4 str. 2011C-3493 13701545 YP_006779011.1 CDS O3K_11600 NC_018658.1 2385728 2388568 R phage replication protein complement(2385728..2388568) Escherichia coli O104:H4 str. 2011C-3493 13701546 YP_006779012.1 CDS O3K_11605 NC_018658.1 2388565 2388954 R hypothetical protein complement(2388565..2388954) Escherichia coli O104:H4 str. 2011C-3493 13701547 YP_006779013.1 CDS O3K_11610 NC_018658.1 2389027 2389257 R hypothetical protein complement(2389027..2389257) Escherichia coli O104:H4 str. 2011C-3493 13701548 YP_006779014.1 CDS O3K_11615 NC_018658.1 2389580 2389879 R hypothetical protein complement(2389580..2389879) Escherichia coli O104:H4 str. 2011C-3493 13701549 YP_006779015.1 CDS O3K_11620 NC_018658.1 2389876 2390121 R COG1846 Transcriptional regulators; hypothetical protein complement(2389876..2390121) Escherichia coli O104:H4 str. 2011C-3493 13701550 YP_006779016.1 CDS O3K_11625 NC_018658.1 2390118 2390321 R hypothetical protein complement(2390118..2390321) Escherichia coli O104:H4 str. 2011C-3493 13701551 YP_006779017.1 CDS O3K_11630 NC_018658.1 2390311 2390631 R hypothetical protein complement(2390311..2390631) Escherichia coli O104:H4 str. 2011C-3493 13701552 YP_006779018.1 CDS O3K_11635 NC_018658.1 2390720 2390833 R hypothetical protein complement(2390720..2390833) Escherichia coli O104:H4 str. 2011C-3493 13701553 YP_006779019.1 CDS O3K_11640 NC_018658.1 2390830 2391072 R hypothetical protein complement(2390830..2391072) Escherichia coli O104:H4 str. 2011C-3493 13701554 YP_006779020.1 CDS O3K_11645 NC_018658.1 2391084 2391371 R hypothetical protein complement(2391084..2391371) Escherichia coli O104:H4 str. 2011C-3493 13701555 YP_006779021.1 CDS O3K_11650 NC_018658.1 2391382 2391720 R hypothetical protein complement(2391382..2391720) Escherichia coli O104:H4 str. 2011C-3493 13701556 YP_006779022.1 CDS O3K_11655 NC_018658.1 2391735 2392013 R DNA-binding protein complement(2391735..2392013) Escherichia coli O104:H4 str. 2011C-3493 13701557 YP_006779023.1 CDS O3K_11660 NC_018658.1 2392105 2392416 D COG2944 Predicted transcriptional regulator; repressor protein C 2392105..2392416 Escherichia coli O104:H4 str. 2011C-3493 13701558 YP_006779024.1 CDS O3K_11665 NC_018658.1 2392505 2393440 D COG0582 Integrase; integrase 2392505..2393440 Escherichia coli O104:H4 str. 2011C-3493 13701559 YP_006779025.1 CDS O3K_11670 NC_018658.1 2393451 2393846 D hypothetical protein 2393451..2393846 Escherichia coli O104:H4 str. 2011C-3493 13701560 YP_006779026.1 CDS O3K_11675 NC_018658.1 2394036 2395016 D COG4139 ABC-type cobalamin transport system, permease component; vtamin B12-transporter permease 2394036..2395016 Escherichia coli O104:H4 str. 2011C-3493 13701561 YP_006779027.1 CDS btuE NC_018658.1 2395079 2395630 D COG0386 Glutathione peroxidase; glutathione peroxidase 2395079..2395630 Escherichia coli O104:H4 str. 2011C-3493 13701562 YP_006779028.1 CDS O3K_11685 NC_018658.1 2395630 2396379 D COG4138 ABC-type cobalamin transport system, ATPase component; vitamin B12-transporter ATPase 2395630..2396379 Escherichia coli O104:H4 str. 2011C-3493 13701563 YP_006779029.1 CDS O3K_11690 NC_018658.1 2396457 2396921 D COG0791 Cell wall-associated hydrolases (invasion-associated proteins); lipoprotein 2396457..2396921 Escherichia coli O104:H4 str. 2011C-3493 13701564 YP_006779030.1 CDS O3K_11695 NC_018658.1 2397168 2397881 D COG2200 FOG: EAL domain; hypothetical protein 2397168..2397881 Escherichia coli O104:H4 str. 2011C-3493 13701636 YP_006779031.1 CDS O3K_11700 NC_018658.1 2397944 2399380 D COG0397 Uncharacterized conserved protein; hypothetical protein 2397944..2399380 Escherichia coli O104:H4 str. 2011C-3493 13701637 YP_006779032.1 CDS O3K_11705 NC_018658.1 2399384 2399575 R COG4256 Hemin uptake protein; hypothetical protein complement(2399384..2399575) Escherichia coli O104:H4 str. 2011C-3493 13701638 YP_006779033.1 CDS O3K_11710 NC_018658.1 2399707 2400753 R COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2399707..2400753) Escherichia coli O104:H4 str. 2011C-3493 13701639 YP_006779034.1 CDS O3K_11715 NC_018658.1 2400910 2401743 R COG1806 Uncharacterized protein conserved in bacteria; PEP synthetase regulatory protein complement(2400910..2401743) Escherichia coli O104:H4 str. 2011C-3493 13701640 YP_006779035.1 CDS O3K_11720 NC_018658.1 2402076 2404454 D COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; phosphoenolpyruvate synthase 2402076..2404454 Escherichia coli O104:H4 str. 2011C-3493 13701641 YP_006779036.1 CDS O3K_11725 NC_018658.1 2404511 2406211 R COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; short chain acyl-CoA synthetase complement(2404511..2406211) Escherichia coli O104:H4 str. 2011C-3493 13701642 YP_006779037.1 CDS O3K_11730 NC_018658.1 2406214 2406507 R COG2440 Ferredoxin-like protein; ferredoxin-like protein FixX complement(2406214..2406507) Escherichia coli O104:H4 str. 2011C-3493 13701643 YP_006779038.1 CDS O3K_11735 NC_018658.1 2406504 2407793 R COG0644 Dehydrogenases (flavoproteins); oxidoreductase complement(2406504..2407793) Escherichia coli O104:H4 str. 2011C-3493 13701644 YP_006779039.1 CDS O3K_11740 NC_018658.1 2407849 2408787 R COG2025 Electron transfer flavoprotein, alpha subunit; electron transfer flavoprotein subunit YdiR complement(2407849..2408787) Escherichia coli O104:H4 str. 2011C-3493 13701645 YP_006779040.1 CDS O3K_11745 NC_018658.1 2408807 2409571 R COG2086 Electron transfer flavoprotein, beta subunit; hypothetical protein complement(2408807..2409571) Escherichia coli O104:H4 str. 2011C-3493 13701646 YP_006779041.1 CDS O3K_11750 NC_018658.1 2409608 2409784 D hypothetical protein 2409608..2409784 Escherichia coli O104:H4 str. 2011C-3493 13701647 YP_006779042.1 CDS O3K_11755 NC_018658.1 2409887 2410798 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 2409887..2410798 Escherichia coli O104:H4 str. 2011C-3493 13701648 YP_006779043.1 CDS O3K_11760 NC_018658.1 2410841 2411992 R COG1960 Acyl-CoA dehydrogenases; putative acyl-CoA dehydrogenase complement(2410841..2411992) Escherichia coli O104:H4 str. 2011C-3493 13701649 YP_006779044.1 CDS O3K_11765 NC_018658.1 2412006 2413601 R COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; acetyl-CoA: acetoacetyl-CoA transferase subunit alpha/beta complement(2412006..2413601) Escherichia coli O104:H4 str. 2011C-3493 13701650 YP_006779045.1 CDS aroD NC_018658.1 2413745 2414503 R COG0710 3-dehydroquinate dehydratase; 3-dehydroquinate dehydratase complement(2413745..2414503) Escherichia coli O104:H4 str. 2011C-3493 13701651 YP_006779046.1 CDS O3K_11775 NC_018658.1 2414534 2415400 R COG0169 Shikimate 5-dehydrogenase; quinate/shikimate dehydrogenase complement(2414534..2415400) Escherichia coli O104:H4 str. 2011C-3493 13701652 YP_006779047.1 CDS O3K_11780 NC_018658.1 2415412 2416677 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2415412..2416677) Escherichia coli O104:H4 str. 2011C-3493 13701653 YP_006779048.1 CDS O3K_11785 NC_018658.1 2416904 2418118 R COG0477 Permeases of the major facilitator superfamily; transporter, MFS superfamily protein complement(2416904..2418118) Escherichia coli O104:H4 str. 2011C-3493 13701654 YP_006779049.1 CDS O3K_11790 NC_018658.1 2418218 2418574 R hypothetical protein complement(2418218..2418574) Escherichia coli O104:H4 str. 2011C-3493 13701655 YP_006779050.1 CDS O3K_11795 NC_018658.1 2419003 2420115 R COG0628 Predicted permease; inner membrane protein complement(2419003..2420115) Escherichia coli O104:H4 str. 2011C-3493 13701656 YP_006779051.1 CDS O3K_11800 NC_018658.1 2420504 2423560 D COG0277 FAD/FMN-containing dehydrogenases; putative FAD-linked oxidoreductase 2420504..2423560 Escherichia coli O104:H4 str. 2011C-3493 13701657 YP_006779052.1 CDS O3K_11805 NC_018658.1 2423557 2423967 D COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; acyl-CoA esterase 2423557..2423967 Escherichia coli O104:H4 str. 2011C-3493 13701658 YP_006779053.1 CDS O3K_11810 NC_018658.1 2423986 2424255 D hypothetical protein 2423986..2424255 Escherichia coli O104:H4 str. 2011C-3493 13701659 YP_006779054.1 CDS sufA NC_018658.1 2424804 2425172 D COG0316 Uncharacterized conserved protein; iron-sulfur cluster assembly scaffold protein 2424804..2425172 Escherichia coli O104:H4 str. 2011C-3493 13701660 YP_006779055.1 CDS O3K_11820 NC_018658.1 2425181 2426668 D COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; cysteine desulfurase activator complex subunit SufB 2425181..2426668 Escherichia coli O104:H4 str. 2011C-3493 13701661 YP_006779056.1 CDS sufC NC_018658.1 2426678 2427424 D COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; cysteine desulfurase 2426678..2427424 Escherichia coli O104:H4 str. 2011C-3493 13701662 YP_006779057.1 CDS O3K_11830 NC_018658.1 2427399 2428670 D COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; cysteine desulfurase activator complex subunit SufD 2427399..2428670 Escherichia coli O104:H4 str. 2011C-3493 13701663 YP_006779058.1 CDS O3K_11835 NC_018658.1 2428667 2429887 D COG0520 Selenocysteine lyase; bifunctional cysteine desulfurase/selenocysteine lyase 2428667..2429887 Escherichia coli O104:H4 str. 2011C-3493 13701664 YP_006779059.1 CDS O3K_11840 NC_018658.1 2429900 2430316 D COG2166 SufE protein probably involved in Fe-S center assembly; cysteine desufuration protein SufE 2429900..2430316 Escherichia coli O104:H4 str. 2011C-3493 13701665 YP_006779060.1 CDS O3K_11845 NC_018658.1 2430465 2431469 D COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 2430465..2431469 Escherichia coli O104:H4 str. 2011C-3493 13701666 YP_006779061.1 CDS O3K_11850 NC_018658.1 2431533 2431769 R COG4238 Murein lipoprotein; murein lipoprotein complement(2431533..2431769) Escherichia coli O104:H4 str. 2011C-3493 13701667 YP_006779062.1 CDS O3K_11855 NC_018658.1 2432080 2433492 R COG0469 Pyruvate kinase; pyruvate kinase complement(2432080..2433492) Escherichia coli O104:H4 str. 2011C-3493 13701668 YP_006779063.1 CDS O3K_11860 NC_018658.1 2434049 2434258 D hypothetical protein 2434049..2434258 Escherichia coli O104:H4 str. 2011C-3493 13701669 YP_006779064.1 CDS O3K_11865 NC_018658.1 2434714 2435340 D COG0437 Fe-S-cluster-containing hydrogenase components 1; hypothetical protein 2434714..2435340 Escherichia coli O104:H4 str. 2011C-3493 13701670 YP_006779065.1 CDS O3K_11870 NC_018658.1 2435361 2437463 D COG2414 Aldehyde:ferredoxin oxidoreductase; oxidoreductase 2435361..2437463 Escherichia coli O104:H4 str. 2011C-3493 13701671 YP_006779066.1 CDS O3K_11875 NC_018658.1 2437467 2438114 D hypothetical protein 2437467..2438114 Escherichia coli O104:H4 str. 2011C-3493 13701672 YP_006779067.1 CDS O3K_11880 NC_018658.1 2438127 2438846 D COG0437 Fe-S-cluster-containing hydrogenase components 1; oxidoreductase, Fe-S subunit 2438127..2438846 Escherichia coli O104:H4 str. 2011C-3493 13701673 YP_006779068.1 CDS O3K_11885 NC_018658.1 2438843 2439628 D thiosulfate reductase cytochrome B subunit 2438843..2439628 Escherichia coli O104:H4 str. 2011C-3493 13701674 YP_006779069.1 CDS O3K_11890 NC_018658.1 2439632 2440444 D hypothetical protein 2439632..2440444 Escherichia coli O104:H4 str. 2011C-3493 13701675 YP_006779070.1 CDS O3K_11895 NC_018658.1 2440456 2442060 R COG4529 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2440456..2442060) Escherichia coli O104:H4 str. 2011C-3493 13701676 YP_006779071.1 CDS O3K_11900 NC_018658.1 2442186 2442491 R COG0113 Delta-aminolevulinic acid dehydratase; putative monooxygenase complement(2442186..2442491) Escherichia coli O104:H4 str. 2011C-3493 13701677 YP_006779072.1 CDS O3K_11905 NC_018658.1 2443064 2444320 D hypothetical protein 2443064..2444320 Escherichia coli O104:H4 str. 2011C-3493 13701680 YP_006779073.1 CDS O3K_11910 NC_018658.1 2444361 2445734 R COG0534 Na+-driven multidrug efflux pump; multidrug efflux protein complement(2444361..2445734) Escherichia coli O104:H4 str. 2011C-3493 13701681 YP_006779074.1 CDS O3K_11915 NC_018658.1 2445949 2446590 D COG0307 Riboflavin synthase alpha chain; riboflavin synthase subunit alpha 2445949..2446590 Escherichia coli O104:H4 str. 2011C-3493 13701682 YP_006779075.1 CDS O3K_11920 NC_018658.1 2446630 2447778 R COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane-fatty-acyl-phospholipid synthase complement(2446630..2447778) Escherichia coli O104:H4 str. 2011C-3493 13701683 YP_006779076.1 CDS O3K_11925 NC_018658.1 2448069 2449280 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2448069..2449280) Escherichia coli O104:H4 str. 2011C-3493 13701684 YP_006779077.1 CDS O3K_11930 NC_018658.1 2449393 2450325 D COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator 2449393..2450325 Escherichia coli O104:H4 str. 2011C-3493 13701685 YP_006779078.1 CDS O3K_11935 NC_018658.1 2450322 2451347 R COG1609 Transcriptional regulators; DNA-binding transcriptional repressor PurR complement(2450322..2451347) Escherichia coli O104:H4 str. 2011C-3493 13701686 YP_006779079.1 CDS O3K_11940 NC_018658.1 2451646 2451735 D hypothetical protein 2451646..2451735 Escherichia coli O104:H4 str. 2011C-3493 13701687 YP_006779080.1 CDS O3K_11945 NC_018658.1 2451901 2453070 D COG2814 Arabinose efflux permease; transporter 2451901..2453070 Escherichia coli O104:H4 str. 2011C-3493 13701688 YP_006779081.1 CDS O3K_11950 NC_018658.1 2453216 2453797 R COG0605 Superoxide dismutase; superoxide dismutase complement(2453216..2453797) Escherichia coli O104:H4 str. 2011C-3493 13701689 YP_006779082.1 CDS O3K_11955 NC_018658.1 2453925 2454740 R COG0791 Cell wall-associated hydrolases (invasion-associated proteins); lipoprotein complement(2453925..2454740) Escherichia coli O104:H4 str. 2011C-3493 13701690 YP_006779083.1 CDS O3K_11960 NC_018658.1 2455074 2455421 D COG0278 Glutaredoxin-related protein; glutaredoxin-4 2455074..2455421 Escherichia coli O104:H4 str. 2011C-3493 13701691 YP_006779084.1 CDS O3K_11965 NC_018658.1 2455472 2460088 R COG1201 Lhr-like helicases; putative ATP-dependent helicase Lhr complement(2455472..2460088) Escherichia coli O104:H4 str. 2011C-3493 13701692 YP_006779085.1 CDS O3K_11970 NC_018658.1 2460181 2460828 R COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; ribonuclease T complement(2460181..2460828) Escherichia coli O104:H4 str. 2011C-3493 13701693 YP_006779086.1 CDS O3K_11975 NC_018658.1 2460931 2461338 R COG0346 Lactoylglutathione lyase and related lyases; glyoxalase I complement(2460931..2461338) Escherichia coli O104:H4 str. 2011C-3493 13701694 YP_006779087.1 CDS O3K_11980 NC_018658.1 2461419 2462516 R COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; N-ethylmaleimide reductase complement(2461419..2462516) Escherichia coli O104:H4 str. 2011C-3493 13701695 YP_006779088.1 CDS O3K_11985 NC_018658.1 2462553 2463152 R COG1309 Transcriptional regulator; putative DNA-binding transcriptional regulator complement(2462553..2463152) Escherichia coli O104:H4 str. 2011C-3493 13701696 YP_006779089.1 CDS O3K_11990 NC_018658.1 2463255 2463494 D COG3313 Predicted Fe-S protein; hypothetical protein 2463255..2463494 Escherichia coli O104:H4 str. 2011C-3493 13701697 YP_006779090.1 CDS O3K_11995 NC_018658.1 2463543 2464439 D COG4989 Predicted oxidoreductase; oxidoreductase 2463543..2464439 Escherichia coli O104:H4 str. 2011C-3493 13701698 YP_006779091.1 CDS O3K_12000 NC_018658.1 2464520 2465041 D COG2032 Cu/Zn superoxide dismutase; superoxide dismutase 2464520..2465041 Escherichia coli O104:H4 str. 2011C-3493 13701699 YP_006779092.1 CDS O3K_12005 NC_018658.1 2465042 2467054 R COG1289 Predicted membrane protein; hypothetical protein complement(2465042..2467054) Escherichia coli O104:H4 str. 2011C-3493 13701700 YP_006779093.1 CDS O3K_12010 NC_018658.1 2467054 2467911 R COG1566 Multidrug resistance efflux pump; undecaprenyl pyrophosphate phosphatase complement(2467054..2467911) Escherichia coli O104:H4 str. 2011C-3493 13701701 YP_006779094.1 CDS O3K_12015 NC_018658.1 2467914 2468150 R hypothetical protein complement(2467914..2468150) Escherichia coli O104:H4 str. 2011C-3493 13701702 YP_006779095.1 CDS O3K_12020 NC_018658.1 2468351 2468785 D COG1846 Transcriptional regulators; transcriptional regulator SlyA 2468351..2468785 Escherichia coli O104:H4 str. 2011C-3493 13701703 YP_006779096.1 CDS O3K_12025 NC_018658.1 2468832 2469299 R COG3133 Outer membrane lipoprotein; outer membrane lipoprotein SlyB complement(2468832..2469299) Escherichia coli O104:H4 str. 2011C-3493 13701704 YP_006779097.1 CDS anmK NC_018658.1 2469573 2470682 D COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases; anhydro-N-acetylmuramic acid kinase 2469573..2470682 Escherichia coli O104:H4 str. 2011C-3493 13701705 YP_006779098.1 CDS O3K_12035 NC_018658.1 2470780 2471109 D COG3895 Predicted periplasmic protein; lysozyme inhibitor 2470780..2471109 Escherichia coli O104:H4 str. 2011C-3493 13701706 YP_006779099.1 CDS O3K_12040 NC_018658.1 2471168 2471824 D COG0259 Pyridoxamine-phosphate oxidase; pyridoxamine 5'-phosphate oxidase 2471168..2471824 Escherichia coli O104:H4 str. 2011C-3493 13701707 YP_006779100.1 CDS O3K_12045 NC_018658.1 2471953 2473227 D COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 2471953..2473227 Escherichia coli O104:H4 str. 2011C-3493 13701708 YP_006779101.1 CDS O3K_12050 NC_018658.1 2473289 2474149 D COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxamine kinase 2473289..2474149 Escherichia coli O104:H4 str. 2011C-3493 13701709 YP_006779102.1 CDS O3K_12055 NC_018658.1 2474193 2474798 R COG0625 Glutathione S-transferase; glutathionine S-transferase complement(2474193..2474798) Escherichia coli O104:H4 str. 2011C-3493 13701710 YP_006779103.1 CDS tppB NC_018658.1 2474904 2476406 R COG3104 Dipeptide/tripeptide permease; putative tripeptide transporter permease complement(2474904..2476406) Escherichia coli O104:H4 str. 2011C-3493 13701711 YP_006779104.1 CDS O3K_12065 NC_018658.1 2476689 2476889 R hypothetical protein complement(2476689..2476889) Escherichia coli O104:H4 str. 2011C-3493 13701712 YP_006779105.1 CDS O3K_12070 NC_018658.1 2477017 2477652 R COG0177 Predicted EndoIII-related endonuclease; endonuclease III complement(2477017..2477652) Escherichia coli O104:H4 str. 2011C-3493 13701713 YP_006779106.1 CDS O3K_12075 NC_018658.1 2477652 2478347 R COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE; electron transport complex protein RsxE complement(2477652..2478347) Escherichia coli O104:H4 str. 2011C-3493 13701714 YP_006779107.1 CDS O3K_12080 NC_018658.1 2478351 2478971 R COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG; electron transport complex protein RnfG complement(2478351..2478971) Escherichia coli O104:H4 str. 2011C-3493 13701715 YP_006779108.1 CDS rnfD NC_018658.1 2478975 2480033 R COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD; electron transport complex protein RnfD complement(2478975..2480033) Escherichia coli O104:H4 str. 2011C-3493 13701716 YP_006779109.1 CDS O3K_12090 NC_018658.1 2480034 2482064 R COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC; electron transport complex protein RnfC complement(2480034..2482064) Escherichia coli O104:H4 str. 2011C-3493 13701787 YP_006779110.1 CDS O3K_12095 NC_018658.1 2482057 2482635 R COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB; electron transport complex protein RnfB complement(2482057..2482635) Escherichia coli O104:H4 str. 2011C-3493 13701788 YP_006779111.1 CDS O3K_12100 NC_018658.1 2482635 2483216 R COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA; electron transport complex protein RsxA complement(2482635..2483216) Escherichia coli O104:H4 str. 2011C-3493 13701789 YP_006779112.1 CDS O3K_12105 NC_018658.1 2483293 2483733 R hypothetical protein complement(2483293..2483733) Escherichia coli O104:H4 str. 2011C-3493 13701790 YP_006779113.1 CDS O3K_12110 NC_018658.1 2483819 2484034 R oriC-binding nucleoid-associated protein complement(2483819..2484034) Escherichia coli O104:H4 str. 2011C-3493 13701791 YP_006779114.1 CDS O3K_12115 NC_018658.1 2484675 2485715 D COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 2484675..2485715 Escherichia coli O104:H4 str. 2011C-3493 13701792 YP_006779115.1 CDS O3K_12120 NC_018658.1 2485750 2486751 R COG1816 Adenosine deaminase; adenosine deaminase complement(2485750..2486751) Escherichia coli O104:H4 str. 2011C-3493 13701793 YP_006779116.1 CDS O3K_12125 NC_018658.1 2486855 2488027 R COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; bifunctional beta-cystathionase and regulator of maltose regulon complement(2486855..2488027) Escherichia coli O104:H4 str. 2011C-3493 13701794 YP_006779117.1 CDS O3K_12130 NC_018658.1 2488037 2489629 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system maltose and glucose-specific transporter subunits IICB complement(2488037..2489629) Escherichia coli O104:H4 str. 2011C-3493 13701795 YP_006779118.1 CDS O3K_12135 NC_018658.1 2489804 2490832 D COG1609 Transcriptional regulators; DNA-binding transcriptional repressor MalI 2489804..2490832 Escherichia coli O104:H4 str. 2011C-3493 13701796 YP_006779119.1 CDS O3K_12140 NC_018658.1 2490944 2491711 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 7-alpha-hydroxysteroid dehydrogenase 2490944..2491711 Escherichia coli O104:H4 str. 2011C-3493 13701797 YP_006779120.1 CDS O3K_12145 NC_018658.1 2491940 2492530 D COG1309 Transcriptional regulator; DNA-binding transcriptional repressor UidR 2491940..2492530 Escherichia coli O104:H4 str. 2011C-3493 13701798 YP_006779121.1 CDS O3K_12150 NC_018658.1 2492919 2494730 D COG3250 Beta-galactosidase/beta-glucuronidase; beta-D-glucuronidase 2492919..2494730 Escherichia coli O104:H4 str. 2011C-3493 13701799 YP_006779122.1 CDS O3K_12155 NC_018658.1 2494727 2496100 D COG2211 Na+/melibiose symporter and related transporters; glucuronide transporter 2494727..2496100 Escherichia coli O104:H4 str. 2011C-3493 13701800 YP_006779123.1 CDS O3K_12160 NC_018658.1 2496139 2497404 D putative outer membrane porin protein 2496139..2497404 Escherichia coli O104:H4 str. 2011C-3493 13701801 YP_006779124.1 CDS O3K_12165 NC_018658.1 2497449 2498957 R COG5339 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2497449..2498957) Escherichia coli O104:H4 str. 2011C-3493 13701802 YP_006779125.1 CDS O3K_12170 NC_018658.1 2499058 2500233 R COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase complement(2499058..2500233) Escherichia coli O104:H4 str. 2011C-3493 13701803 YP_006779126.1 CDS O3K_12175 NC_018658.1 2500432 2502078 D COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase FumA 2500432..2502078 Escherichia coli O104:H4 str. 2011C-3493 13701804 YP_006779127.1 CDS fumC NC_018658.1 2502221 2503624 D COG0114 Fumarase; fumarate hydratase 2502221..2503624 Escherichia coli O104:H4 str. 2011C-3493 13701805 YP_006779128.1 CDS O3K_12185 NC_018658.1 2503621 2504550 R DNA replication terminus site-binding protein complement(2503621..2504550) Escherichia coli O104:H4 str. 2011C-3493 13701806 YP_006779129.1 CDS O3K_12190 NC_018658.1 2504626 2505927 R COG0642 Signal transduction histidine kinase; sensor protein RstB complement(2504626..2505927) Escherichia coli O104:H4 str. 2011C-3493 13701807 YP_006779130.1 CDS O3K_12195 NC_018658.1 2505931 2506650 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator RstA complement(2505931..2506650) Escherichia coli O104:H4 str. 2011C-3493 13701808 YP_006779131.1 CDS O3K_12200 NC_018658.1 2506779 2507114 D COG3136 Uncharacterized membrane protein required for alginate biosynthesis; GlpM family protein 2506779..2507114 Escherichia coli O104:H4 str. 2011C-3493 13701809 YP_006779132.1 CDS O3K_12205 NC_018658.1 2507111 2507833 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dihydromonapterin reductase complement(2507111..2507833) Escherichia coli O104:H4 str. 2011C-3493 13701810 YP_006779133.1 CDS O3K_12210 NC_018658.1 2507870 2509252 R COG0531 Amino acid transporters; putative arginine/ornithine antiporter complement(2507870..2509252) Escherichia coli O104:H4 str. 2011C-3493 13701811 YP_006779134.1 CDS O3K_12215 NC_018658.1 2509438 2510382 R hypothetical protein complement(2509438..2510382) Escherichia coli O104:H4 str. 2011C-3493 13701812 YP_006779135.1 CDS pntA NC_018658.1 2510907 2512439 D COG3288 NAD/NADP transhydrogenase alpha subunit; NAD(P) transhydrogenase subunit alpha 2510907..2512439 Escherichia coli O104:H4 str. 2011C-3493 13701813 YP_006779136.1 CDS pntB NC_018658.1 2512450 2513838 D COG1282 NAD/NADP transhydrogenase beta subunit; pyridine nucleotide transhydrogenase 2512450..2513838 Escherichia coli O104:H4 str. 2011C-3493 13701814 YP_006779137.1 CDS tqsA NC_018658.1 2513863 2514897 R COG0628 Predicted permease; pheromone autoinducer 2 transporter complement(2513863..2514897) Escherichia coli O104:H4 str. 2011C-3493 13701815 YP_006779138.1 CDS O3K_12235 NC_018658.1 2515309 2515674 D COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux system protein MdtJ 2515309..2515674 Escherichia coli O104:H4 str. 2011C-3493 13701816 YP_006779139.1 CDS O3K_12240 NC_018658.1 2515661 2515990 D COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux system protein MdtI 2515661..2515990 Escherichia coli O104:H4 str. 2011C-3493 13701817 YP_006779140.1 CDS O3K_12245 NC_018658.1 2516029 2516850 R COG3591 V8-like Glu-specific endopeptidase; metallopeptidase complement(2516029..2516850) Escherichia coli O104:H4 str. 2011C-3493 13701818 YP_006779141.1 CDS O3K_12250 NC_018658.1 2516950 2517033 R hypothetical protein complement(2516950..2517033) Escherichia coli O104:H4 str. 2011C-3493 13701819 YP_006779142.1 CDS O3K_12255 NC_018658.1 2517126 2517434 R acid shock protein complement(2517126..2517434) Escherichia coli O104:H4 str. 2011C-3493 13701820 YP_006779143.1 CDS O3K_12260 NC_018658.1 2517858 2519111 R COG0477 Permeases of the major facilitator superfamily; transporter, MFS type complement(2517858..2519111) Escherichia coli O104:H4 str. 2011C-3493 13701821 YP_006779144.1 CDS O3K_12265 NC_018658.1 2519218 2520111 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 2519218..2520111 Escherichia coli O104:H4 str. 2011C-3493 13701822 YP_006779145.1 CDS O3K_12270 NC_018658.1 2520246 2521466 D COG1940 Transcriptional regulator/sugar kinase; NAGC-like transcriptional regulator 2520246..2521466 Escherichia coli O104:H4 str. 2011C-3493 13701823 YP_006779146.1 CDS O3K_12275 NC_018658.1 2521591 2522286 D COG0132 Dethiobiotin synthetase; putative dithiobiotin synthetase 2521591..2522286 Escherichia coli O104:H4 str. 2011C-3493 13701824 YP_006779147.1 CDS O3K_12280 NC_018658.1 2522302 2523495 R COG0038 Chloride channel protein EriC; putative voltage-gated ClC-type chloride channel ClcB complement(2522302..2523495) Escherichia coli O104:H4 str. 2011C-3493 13701825 YP_006779148.1 CDS O3K_12285 NC_018658.1 2523690 2524304 R COG3381 Uncharacterized component of anaerobic dehydrogenases; twin-argninine leader-binding protein DmsD complement(2523690..2524304) Escherichia coli O104:H4 str. 2011C-3493 13701826 YP_006779149.1 CDS O3K_12290 NC_018658.1 2524347 2525201 R COG3302 DMSO reductase anchor subunit; oxidoreductase, membrane subunit complement(2524347..2525201) Escherichia coli O104:H4 str. 2011C-3493 13701827 YP_006779150.1 CDS O3K_12295 NC_018658.1 2525203 2525754 R COG0437 Fe-S-cluster-containing hydrogenase components 1; anaerobic dimethyl sulfoxide reductase chain ynfG complement(2525203..2525754) Escherichia coli O104:H4 str. 2011C-3493 13701828 YP_006779151.1 CDS O3K_12300 NC_018658.1 2525795 2526958 R COG0582 Integrase; prophage DLP12 integrase complement(2525795..2526958) Escherichia coli O104:H4 str. 2011C-3493 13701829 YP_006779152.1 CDS O3K_12305 NC_018658.1 2526814 2527185 R COG2452 Predicted site-specific integrase-resolvase; Excisionase complement(2526814..2527185) Escherichia coli O104:H4 str. 2011C-3493 13701830 YP_006779153.1 CDS O3K_12310 NC_018658.1 2527220 2527471 R hypothetical protein complement(2527220..2527471) Escherichia coli O104:H4 str. 2011C-3493 13701831 YP_006779154.1 CDS O3K_12315 NC_018658.1 2527519 2528199 R Exonuclease complement(2527519..2528199) Escherichia coli O104:H4 str. 2011C-3493 13701832 YP_006779155.1 CDS O3K_12320 NC_018658.1 2528196 2528981 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Recombination protein bet from phage origin complement(2528196..2528981) Escherichia coli O104:H4 str. 2011C-3493 13701833 YP_006779156.1 CDS O3K_12325 NC_018658.1 2528987 2529283 R putative host-nuclease inhibitor protein Gam of bacteriophage complement(2528987..2529283) Escherichia coli O104:H4 str. 2011C-3493 13701834 YP_006779157.1 CDS O3K_12335 NC_018658.1 2531460 2531846 R hypothetical protein complement(2531460..2531846) Escherichia coli O104:H4 str. 2011C-3493 13701835 YP_006779158.1 CDS kil NC_018658.1 2531930 2532151 R FtsZ inhibitor protein complement(2531930..2532151) Escherichia coli O104:H4 str. 2011C-3493 13701836 YP_006779159.1 CDS O3K_12345 NC_018658.1 2532608 2532817 D hypothetical protein 2532608..2532817 Escherichia coli O104:H4 str. 2011C-3493 13701837 YP_006779160.1 CDS O3K_12350 NC_018658.1 2532921 2533151 D hypothetical protein 2532921..2533151 Escherichia coli O104:H4 str. 2011C-3493 13701838 YP_006779161.1 CDS O3K_12355 NC_018658.1 2533177 2533890 R hypothetical protein complement(2533177..2533890) Escherichia coli O104:H4 str. 2011C-3493 13701839 YP_006779162.1 CDS O3K_12360 NC_018658.1 2533894 2534277 R Antitermination protein N complement(2533894..2534277) Escherichia coli O104:H4 str. 2011C-3493 13701840 YP_006779163.1 CDS O3K_12365 NC_018658.1 2534772 2535548 R hypothetical protein complement(2534772..2535548) Escherichia coli O104:H4 str. 2011C-3493 13701841 YP_006779164.1 CDS O3K_12370 NC_018658.1 2535536 2536078 R hypothetical protein complement(2535536..2536078) Escherichia coli O104:H4 str. 2011C-3493 13701842 YP_006779165.1 CDS O3K_12375 NC_018658.1 2536125 2536838 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Repressor protein CI from prophage complement(2536125..2536838) Escherichia coli O104:H4 str. 2011C-3493 13701843 YP_006779166.1 CDS O3K_12380 NC_018658.1 2536939 2537139 D regulatory protein cro 2536939..2537139 Escherichia coli O104:H4 str. 2011C-3493 13701844 YP_006779167.1 CDS O3K_12385 NC_018658.1 2537278 2537574 D regulatory protein CII from prophage 2537278..2537574 Escherichia coli O104:H4 str. 2011C-3493 13701845 YP_006779168.1 CDS O3K_12390 NC_018658.1 2537589 2537807 D hypothetical protein 2537589..2537807 Escherichia coli O104:H4 str. 2011C-3493 13701846 YP_006779169.1 CDS O3K_12395 NC_018658.1 2537909 2538910 D hypothetical protein 2537909..2538910 Escherichia coli O104:H4 str. 2011C-3493 13701847 YP_006779170.1 CDS O3K_12400 NC_018658.1 2538917 2539657 D COG1484 DNA replication protein; putative replication protein 2538917..2539657 Escherichia coli O104:H4 str. 2011C-3493 13701848 YP_006779171.1 CDS O3K_12405 NC_018658.1 2539683 2540453 D COG1349 Transcriptional regulators of sugar metabolism; hypothetical protein 2539683..2540453 Escherichia coli O104:H4 str. 2011C-3493 13701849 YP_006779172.1 CDS O3K_12410 NC_018658.1 2540469 2540864 D hypothetical protein 2540469..2540864 Escherichia coli O104:H4 str. 2011C-3493 13701850 YP_006779173.1 CDS O3K_12415 NC_018658.1 2540921 2541505 D hypothetical protein 2540921..2541505 Escherichia coli O104:H4 str. 2011C-3493 13701851 YP_006779174.1 CDS O3K_12420 NC_018658.1 2541621 2541725 D hypothetical protein 2541621..2541725 Escherichia coli O104:H4 str. 2011C-3493 13701852 YP_006779175.1 CDS O3K_12425 NC_018658.1 2541914 2542126 D cell killing protein encoded within cryptic prophage CP-933P 2541914..2542126 Escherichia coli O104:H4 str. 2011C-3493 13701853 YP_006779176.1 CDS O3K_12430 NC_018658.1 2542336 2542515 D bacteriophage protein 2542336..2542515 Escherichia coli O104:H4 str. 2011C-3493 13701854 YP_006779177.1 CDS O3K_12435 NC_018658.1 2542534 2543019 D COG3654 Prophage maintenance system killer protein; bacteriophage protein 2542534..2543019 Escherichia coli O104:H4 str. 2011C-3493 13701855 YP_006779178.1 CDS O3K_12440 NC_018658.1 2543070 2543387 R COG2944 Predicted transcriptional regulator; DNA-binding protein complement(2543070..2543387) Escherichia coli O104:H4 str. 2011C-3493 13701856 YP_006779179.1 CDS O3K_12445 NC_018658.1 2543495 2543749 R COG4737 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2543495..2543749) Escherichia coli O104:H4 str. 2011C-3493 13701857 YP_006779180.1 CDS O3K_12450 NC_018658.1 2544094 2544765 D putative antirepressor protein Ant from prophage 2544094..2544765 Escherichia coli O104:H4 str. 2011C-3493 13701858 YP_006779181.1 CDS O3K_12455 NC_018658.1 2544820 2545230 D putative ninB protein 2544820..2545230 Escherichia coli O104:H4 str. 2011C-3493 13701859 YP_006779182.1 CDS O3K_12460 NC_018658.1 2545227 2545418 D NinE protein 2545227..2545418 Escherichia coli O104:H4 str. 2011C-3493 13701860 YP_006779183.1 CDS O3K_12465 NC_018658.1 2545442 2545732 D hypothetical protein 2545442..2545732 Escherichia coli O104:H4 str. 2011C-3493 13701861 YP_006779184.1 CDS O3K_12470 NC_018658.1 2545729 2546091 D COG4570 Holliday junction resolvase; crossover junction endodeoxyribonuclease 2545729..2546091 Escherichia coli O104:H4 str. 2011C-3493 13701862 YP_006779185.1 CDS O3K_12475 NC_018658.1 2546091 2546285 D Protein ninH from prophage 2546091..2546285 Escherichia coli O104:H4 str. 2011C-3493 13701863 YP_006779186.1 CDS O3K_12480 NC_018658.1 2546278 2546712 D antitermination protein Q 2546278..2546712 Escherichia coli O104:H4 str. 2011C-3493 13701864 YP_006779187.1 CDS O3K_12485 NC_018658.1 2547478 2549388 D hypothetical protein 2547478..2549388 Escherichia coli O104:H4 str. 2011C-3493 13701865 YP_006779188.1 CDS O3K_12490 NC_018658.1 2549527 2549709 D hypothetical protein 2549527..2549709 Escherichia coli O104:H4 str. 2011C-3493 13701866 YP_006779189.1 CDS O3K_12495 NC_018658.1 2549735 2549980 D hypothetical protein 2549735..2549980 Escherichia coli O104:H4 str. 2011C-3493 13701867 YP_006779190.1 CDS O3K_12500 NC_018658.1 2550057 2550272 D lysis protein S of prophage CP-933V 2550057..2550272 Escherichia coli O104:H4 str. 2011C-3493 13701938 YP_006779191.1 CDS O3K_12505 NC_018658.1 2550277 2550810 D COG3772 Phage-related lysozyme (muraminidase); endolysin 2550277..2550810 Escherichia coli O104:H4 str. 2011C-3493 13701939 YP_006779192.1 CDS O3K_12510 NC_018658.1 2551031 2551144 D hypothetical protein 2551031..2551144 Escherichia coli O104:H4 str. 2011C-3493 13701940 YP_006779193.1 CDS O3K_12515 NC_018658.1 2551146 2551604 D endopeptidase 2551146..2551604 Escherichia coli O104:H4 str. 2011C-3493 13701941 YP_006779194.1 CDS O3K_12520 NC_018658.1 2551685 2552266 R lipopolysaccharide core heptose(II)-phosphate phosphatase complement(2551685..2552266) Escherichia coli O104:H4 str. 2011C-3493 13701942 YP_006779195.1 CDS O3K_12525 NC_018658.1 2552869 2553684 D small subunit terminase 2552869..2553684 Escherichia coli O104:H4 str. 2011C-3493 13701943 YP_006779196.1 CDS O3K_12530 NC_018658.1 2553665 2555371 D putative large subunit terminase 2553665..2555371 Escherichia coli O104:H4 str. 2011C-3493 13701944 YP_006779197.1 CDS O3K_12535 NC_018658.1 2555371 2557515 D putative portal protein 2555371..2557515 Escherichia coli O104:H4 str. 2011C-3493 13701945 YP_006779198.1 CDS O3K_12540 NC_018658.1 2557673 2558680 D COG0061 Predicted sugar kinase; hypothetical protein 2557673..2558680 Escherichia coli O104:H4 str. 2011C-3493 13701946 YP_006779199.1 CDS O3K_12545 NC_018658.1 2558703 2559917 D hypothetical protein 2558703..2559917 Escherichia coli O104:H4 str. 2011C-3493 13701947 YP_006779200.1 CDS O3K_12550 NC_018658.1 2559972 2560361 D hypothetical protein 2559972..2560361 Escherichia coli O104:H4 str. 2011C-3493 13701948 YP_006779201.1 CDS O3K_12555 NC_018658.1 2560412 2560873 D hypothetical protein 2560412..2560873 Escherichia coli O104:H4 str. 2011C-3493 13701949 YP_006779202.1 CDS O3K_12560 NC_018658.1 2560857 2561420 D hypothetical protein 2560857..2561420 Escherichia coli O104:H4 str. 2011C-3493 13701950 YP_006779203.1 CDS O3K_12565 NC_018658.1 2561420 2562070 D hypothetical protein 2561420..2562070 Escherichia coli O104:H4 str. 2011C-3493 13701951 YP_006779204.1 CDS O3K_12570 NC_018658.1 2562067 2563974 D putative tail fiber protein 2562067..2563974 Escherichia coli O104:H4 str. 2011C-3493 13701952 YP_006779205.1 CDS O3K_12575 NC_018658.1 2564615 2564842 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; hypothetical protein 2564615..2564842 Escherichia coli O104:H4 str. 2011C-3493 13701953 YP_006779206.1 CDS O3K_12580 NC_018658.1 2565183 2566808 D hypothetical protein 2565183..2566808 Escherichia coli O104:H4 str. 2011C-3493 13701954 YP_006779207.1 CDS O3K_12585 NC_018658.1 2566805 2568073 D COG4733 Phage-related protein, tail component; putative tail tip fiber protein 2566805..2568073 Escherichia coli O104:H4 str. 2011C-3493 13701955 YP_006779208.1 CDS O3K_12590 NC_018658.1 2568088 2568366 D outer membrane protein 2568088..2568366 Escherichia coli O104:H4 str. 2011C-3493 13701956 YP_006779209.1 CDS O3K_12595 NC_018658.1 2568372 2568989 D hypothetical protein 2568372..2568989 Escherichia coli O104:H4 str. 2011C-3493 13701957 YP_006779210.1 CDS O3K_12600 NC_018658.1 2569081 2569806 D outer membrane precursor Lom 2569081..2569806 Escherichia coli O104:H4 str. 2011C-3493 13701958 YP_006779211.1 CDS O3K_12605 NC_018658.1 2570041 2570181 D hypothetical protein 2570041..2570181 Escherichia coli O104:H4 str. 2011C-3493 13701959 YP_006779212.1 CDS O3K_12610 NC_018658.1 2570238 2570639 D hypothetical protein 2570238..2570639 Escherichia coli O104:H4 str. 2011C-3493 13701960 YP_006779213.1 CDS O3K_12615 NC_018658.1 2570731 2571387 D hypothetical protein 2570731..2571387 Escherichia coli O104:H4 str. 2011C-3493 13701961 YP_006779214.1 CDS O3K_12620 NC_018658.1 2571390 2571836 D hypothetical protein 2571390..2571836 Escherichia coli O104:H4 str. 2011C-3493 13701962 YP_006779215.1 CDS O3K_12625 NC_018658.1 2571846 2572097 D hypothetical protein 2571846..2572097 Escherichia coli O104:H4 str. 2011C-3493 13701963 YP_006779216.1 CDS O3K_12630 NC_018658.1 2572108 2573373 D hypothetical protein 2572108..2573373 Escherichia coli O104:H4 str. 2011C-3493 13701964 YP_006779217.1 CDS O3K_12635 NC_018658.1 2573442 2581793 D COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); hypothetical protein 2573442..2581793 Escherichia coli O104:H4 str. 2011C-3493 13701965 YP_006779218.1 CDS O3K_12640 NC_018658.1 2581917 2582192 D hypothetical protein 2581917..2582192 Escherichia coli O104:H4 str. 2011C-3493 13701966 YP_006779219.1 CDS O3K_12645 NC_018658.1 2582194 2582697 R hypothetical protein complement(2582194..2582697) Escherichia coli O104:H4 str. 2011C-3493 13701967 YP_006779220.1 CDS O3K_12650 NC_018658.1 2582694 2583209 R hypothetical protein complement(2582694..2583209) Escherichia coli O104:H4 str. 2011C-3493 13701968 YP_006779221.1 CDS O3K_12655 NC_018658.1 2583211 2584047 R hypothetical protein complement(2583211..2584047) Escherichia coli O104:H4 str. 2011C-3493 13701969 YP_006779222.1 CDS O3K_12660 NC_018658.1 2584034 2584318 R hypothetical protein complement(2584034..2584318) Escherichia coli O104:H4 str. 2011C-3493 13701970 YP_006779223.1 CDS O3K_12665 NC_018658.1 2584315 2584536 R COG1734 DnaK suppressor protein; putative C4-type zinc finger protein complement(2584315..2584536) Escherichia coli O104:H4 str. 2011C-3493 13701971 YP_006779224.1 CDS O3K_12670 NC_018658.1 2584584 2585219 R COG3561 Phage anti-repressor protein; phage anti-repressor protein AntB complement(2584584..2585219) Escherichia coli O104:H4 str. 2011C-3493 13701972 YP_006779225.1 CDS O3K_12675 NC_018658.1 2585627 2585740 R COG0437 Fe-S-cluster-containing hydrogenase components 1; dimethyl sulfoxide reductase subunit B complement(2585627..2585740) Escherichia coli O104:H4 str. 2011C-3493 13701973 YP_006779226.1 CDS O3K_12680 NC_018658.1 2585751 2588174 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase subunit complement(2585751..2588174) Escherichia coli O104:H4 str. 2011C-3493 13701974 YP_006779227.1 CDS O3K_12685 NC_018658.1 2588235 2590661 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase subunit complement(2588235..2590661) Escherichia coli O104:H4 str. 2011C-3493 13701975 YP_006779228.1 CDS O3K_12690 NC_018658.1 2590860 2591165 R hypothetical protein complement(2590860..2591165) Escherichia coli O104:H4 str. 2011C-3493 13701976 YP_006779229.1 CDS O3K_12695 NC_018658.1 2591273 2591983 D lipoprotein 2591273..2591983 Escherichia coli O104:H4 str. 2011C-3493 13701977 YP_006779230.1 CDS O3K_12700 NC_018658.1 2591986 2592546 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; spermidine N1-acetyltransferase complement(2591986..2592546) Escherichia coli O104:H4 str. 2011C-3493 13701978 YP_006779231.1 CDS O3K_12705 NC_018658.1 2592581 2592922 R hypothetical protein complement(2592581..2592922) Escherichia coli O104:H4 str. 2011C-3493 13701979 YP_006779232.1 CDS O3K_12710 NC_018658.1 2593057 2593383 D COG1742 Uncharacterized conserved protein; hypothetical protein 2593057..2593383 Escherichia coli O104:H4 str. 2011C-3493 13701980 YP_006779233.1 CDS O3K_12715 NC_018658.1 2593589 2594803 D COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; bifunctional D-altronate/D-mannonate dehydratase 2593589..2594803 Escherichia coli O104:H4 str. 2011C-3493 13701981 YP_006779234.1 CDS O3K_12720 NC_018658.1 2594815 2595834 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase 2594815..2595834 Escherichia coli O104:H4 str. 2011C-3493 13701982 YP_006779235.1 CDS O3K_12725 NC_018658.1 2595976 2597259 D COG0477 Permeases of the major facilitator superfamily; transporter 2595976..2597259 Escherichia coli O104:H4 str. 2011C-3493 13701983 YP_006779236.1 CDS O3K_12730 NC_018658.1 2597348 2598808 D COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannonate dehydrogenase 2597348..2598808 Escherichia coli O104:H4 str. 2011C-3493 13701984 YP_006779237.1 CDS O3K_12735 NC_018658.1 2598844 2599047 R selenoprotein ydfZ complement(2598844..2599047) Escherichia coli O104:H4 str. 2011C-3493 13701985 YP_006779238.1 CDS O3K_12740 NC_018658.1 2599225 2599911 R COG1802 Transcriptional regulators; hypothetical protein complement(2599225..2599911) Escherichia coli O104:H4 str. 2011C-3493 13701986 YP_006779239.1 CDS O3K_12745 NC_018658.1 2600000 2600746 R COG4221 Short-chain alcohol dehydrogenase of unknown specificity; malonic semialdehyde reductase complement(2600000..2600746) Escherichia coli O104:H4 str. 2011C-3493 13701987 YP_006779240.1 CDS O3K_12750 NC_018658.1 2600883 2602928 D COG0339 Zn-dependent oligopeptidases; dipeptidyl carboxypeptidase II 2600883..2602928 Escherichia coli O104:H4 str. 2011C-3493 13701988 YP_006779241.1 CDS O3K_12755 NC_018658.1 2602973 2603491 R COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein complement(2602973..2603491) Escherichia coli O104:H4 str. 2011C-3493 13701989 YP_006779242.1 CDS O3K_12760 NC_018658.1 2603767 2604159 D COG3111 Uncharacterized conserved protein; hypothetical protein 2603767..2604159 Escherichia coli O104:H4 str. 2011C-3493 13701990 YP_006779243.1 CDS O3K_12765 NC_018658.1 2604414 2605304 D COG2199 FOG: GGDEF domain; diguanylate cyclase 2604414..2605304 Escherichia coli O104:H4 str. 2011C-3493 13701991 YP_006779244.1 CDS O3K_12770 NC_018658.1 2605524 2605619 R hypothetical protein complement(2605524..2605619) Escherichia coli O104:H4 str. 2011C-3493 13701992 YP_006779245.1 CDS O3K_12775 NC_018658.1 2605746 2606933 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2605746..2606933) Escherichia coli O104:H4 str. 2011C-3493 13701993 YP_006779246.1 CDS O3K_12780 NC_018658.1 2607128 2608027 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; O-acetylserine/cysteine export protein 2607128..2608027 Escherichia coli O104:H4 str. 2011C-3493 13701994 YP_006779247.1 CDS O3K_12785 NC_018658.1 2608072 2608770 R COG2188 Transcriptional regulators; transcriptional regulator complement(2608072..2608770) Escherichia coli O104:H4 str. 2011C-3493 13701995 YP_006779248.1 CDS O3K_12790 NC_018658.1 2608969 2609280 D COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 2608969..2609280 Escherichia coli O104:H4 str. 2011C-3493 13701996 YP_006779249.1 CDS O3K_12795 NC_018658.1 2609395 2610717 D COG1455 Phosphotransferase system cellobiose-specific component IIC; putative phosphotransferase system IIC component 2609395..2610717 Escherichia coli O104:H4 str. 2011C-3493 13701997 YP_006779250.1 CDS O3K_12800 NC_018658.1 2610745 2611056 D COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 2610745..2611056 Escherichia coli O104:H4 str. 2011C-3493 13701998 YP_006779251.1 CDS O3K_12805 NC_018658.1 2611112 2612785 D COG0789 Predicted transcriptional regulators; carbohydrate-specific outer membrane porin 2611112..2612785 Escherichia coli O104:H4 str. 2011C-3493 13701999 YP_006779252.1 CDS celA NC_018658.1 2612810 2614249 D COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; 6-phospho-beta-glucosidase 2612810..2614249 Escherichia coli O104:H4 str. 2011C-3493 13702000 YP_006779253.1 CDS O3K_12815 NC_018658.1 2614306 2614524 R hypothetical protein complement(2614306..2614524) Escherichia coli O104:H4 str. 2011C-3493 13702001 YP_006779254.1 CDS O3K_12820 NC_018658.1 2614556 2614939 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator MarA complement(2614556..2614939) Escherichia coli O104:H4 str. 2011C-3493 13702002 YP_006779255.1 CDS O3K_12825 NC_018658.1 2614959 2615393 R COG1846 Transcriptional regulators; DNA-binding transcriptional repressor MarR complement(2614959..2615393) Escherichia coli O104:H4 str. 2011C-3493 13702003 YP_006779256.1 CDS O3K_12830 NC_018658.1 2615605 2616270 D COG2095 Multiple antibiotic transporter; inner membrane protein 2615605..2616270 Escherichia coli O104:H4 str. 2011C-3493 13702004 YP_006779257.1 CDS O3K_12835 NC_018658.1 2616295 2617485 R COG2814 Arabinose efflux permease; putative arabinose transporter complement(2616295..2617485) Escherichia coli O104:H4 str. 2011C-3493 13702005 YP_006779258.1 CDS O3K_12840 NC_018658.1 2617635 2617883 R hypothetical protein complement(2617635..2617883) Escherichia coli O104:H4 str. 2011C-3493 13702006 YP_006779259.1 CDS O3K_12845 NC_018658.1 2618290 2618748 R hypothetical protein complement(2618290..2618748) Escherichia coli O104:H4 str. 2011C-3493 13702007 YP_006779260.1 CDS O3K_12850 NC_018658.1 2618826 2619707 R COG0583 Transcriptional regulator; LysR family transcriptional regulator complement(2618826..2619707) Escherichia coli O104:H4 str. 2011C-3493 13702008 YP_006779261.1 CDS O3K_12855 NC_018658.1 2619808 2621196 D COG1012 NAD-dependent aldehyde dehydrogenases; putative succinate-semialdehyde dehydrogenase 2619808..2621196 Escherichia coli O104:H4 str. 2011C-3493 13702009 YP_006779262.1 CDS O3K_12860 NC_018658.1 2621260 2622186 D COG2066 Glutaminase; glutaminase 2621260..2622186 Escherichia coli O104:H4 str. 2011C-3493 13702010 YP_006779263.1 CDS O3K_12865 NC_018658.1 2622186 2622545 D hypothetical protein 2622186..2622545 Escherichia coli O104:H4 str. 2011C-3493 13702011 YP_006779264.1 CDS O3K_12870 NC_018658.1 2622684 2624102 D COG2199 FOG: GGDEF domain; hypothetical protein 2622684..2624102 Escherichia coli O104:H4 str. 2011C-3493 13702012 YP_006779265.1 CDS O3K_12875 NC_018658.1 2624329 2625780 D COG0246 Mannitol-1-phosphate/altronate dehydrogenases; altronate oxidoreductase 2624329..2625780 Escherichia coli O104:H4 str. 2011C-3493 13702013 YP_006779266.1 CDS O3K_12880 NC_018658.1 2625987 2626901 D COG3781 Predicted membrane protein; hypothetical protein 2625987..2626901 Escherichia coli O104:H4 str. 2011C-3493 13702014 YP_006779267.1 CDS O3K_12885 NC_018658.1 2626905 2627663 R COG4106 Trans-aconitate methyltransferase; trans-aconitate 2-methyltransferase complement(2626905..2627663) Escherichia coli O104:H4 str. 2011C-3493 13702015 YP_006779268.1 CDS O3K_12890 NC_018658.1 2627720 2628010 R COG1359 Uncharacterized conserved protein; autoinducer-2 (AI-2) modifying protein LsrG complement(2627720..2628010) Escherichia coli O104:H4 str. 2011C-3493 13702016 YP_006779269.1 CDS O3K_12895 NC_018658.1 2628034 2628909 R COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes; autoinducer 2 aldolase complement(2628034..2628909) Escherichia coli O104:H4 str. 2011C-3493 13702017 YP_006779270.1 CDS O3K_12900 NC_018658.1 2628936 2629958 R COG1879 ABC-type sugar transport system, periplasmic component; autoinducer 2-binding protein lsrB complement(2628936..2629958) Escherichia coli O104:H4 str. 2011C-3493 13702018 YP_006779271.1 CDS O3K_12905 NC_018658.1 2629970 2630962 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; autoinducer 2 import system permease LsrD complement(2629970..2630962) Escherichia coli O104:H4 str. 2011C-3493 13702090 YP_006779272.1 CDS O3K_12910 NC_018658.1 2630962 2631990 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; autoinducer 2 ABC transporter permease LsrC complement(2630962..2631990) Escherichia coli O104:H4 str. 2011C-3493 13702091 YP_006779273.1 CDS O3K_12915 NC_018658.1 2631984 2633519 R COG1129 ABC-type sugar transport system, ATPase component; autoinducer 2 ABC transporter ATP-binding protein LsrA complement(2631984..2633519) Escherichia coli O104:H4 str. 2011C-3493 13702092 YP_006779274.1 CDS O3K_12920 NC_018658.1 2633768 2634721 D COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; transcriptional regulator LsrR 2633768..2634721 Escherichia coli O104:H4 str. 2011C-3493 13702093 YP_006779275.1 CDS O3K_12925 NC_018658.1 2634800 2636392 D COG1070 Sugar (pentulose and hexulose) kinases; autoinducer-2 (AI-2) kinase 2634800..2636392 Escherichia coli O104:H4 str. 2011C-3493 13702094 YP_006779276.1 CDS O3K_12930 NC_018658.1 2636923 2640900 D COG5295 Autotransporter adhesin; lipoprotein 2636923..2640900 Escherichia coli O104:H4 str. 2011C-3493 13702095 YP_006779277.1 CDS O3K_12935 NC_018658.1 2640944 2642344 D COG3468 Type V secretory pathway, adhesin AidA; putative lipoprotein/autotransporter domain-containing protein 2640944..2642344 Escherichia coli O104:H4 str. 2011C-3493 13702096 YP_006779278.1 CDS O3K_12940 NC_018658.1 2642553 2642819 D COG1396 Predicted transcriptional regulators; antitoxin HipB 2642553..2642819 Escherichia coli O104:H4 str. 2011C-3493 13702097 YP_006779279.1 CDS O3K_12945 NC_018658.1 2642819 2644141 D COG3550 Uncharacterized protein related to capsule biosynthesis enzymes; regulator with hipB 2642819..2644141 Escherichia coli O104:H4 str. 2011C-3493 13702098 YP_006779280.1 CDS O3K_12950 NC_018658.1 2644459 2644638 D COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator 2644459..2644638 Escherichia coli O104:H4 str. 2011C-3493 13702099 YP_006779281.1 CDS O3K_12955 NC_018658.1 2644532 2644741 D hypothetical protein 2644532..2644741 Escherichia coli O104:H4 str. 2011C-3493 13702100 YP_006779282.1 CDS O3K_12960 NC_018658.1 2645094 2645657 D COG3539 P pilus assembly protein, pilin FimA; major fimbrial subunit FmlA 2645094..2645657 Escherichia coli O104:H4 str. 2011C-3493 13702101 YP_006779283.1 CDS O3K_12965 NC_018658.1 2645991 2646701 D COG3121 P pilus assembly protein, chaperone PapD; putative fimbrial chaperone protein 2645991..2646701 Escherichia coli O104:H4 str. 2011C-3493 13702102 YP_006779284.1 CDS O3K_12970 NC_018658.1 2646743 2649394 D COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 2646743..2649394 Escherichia coli O104:H4 str. 2011C-3493 13702103 YP_006779285.1 CDS O3K_12975 NC_018658.1 2649408 2649938 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 2649408..2649938 Escherichia coli O104:H4 str. 2011C-3493 13702104 YP_006779286.1 CDS O3K_12980 NC_018658.1 2649951 2650454 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 2649951..2650454 Escherichia coli O104:H4 str. 2011C-3493 13702105 YP_006779287.1 CDS O3K_12985 NC_018658.1 2650513 2651427 D fimbrial-like adhesin protein 2650513..2651427 Escherichia coli O104:H4 str. 2011C-3493 13702106 YP_006779288.1 CDS O3K_12990 NC_018658.1 2651761 2654040 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase 2651761..2654040 Escherichia coli O104:H4 str. 2011C-3493 13702107 YP_006779289.1 CDS O3K_12995 NC_018658.1 2654288 2654485 D hypothetical protein 2654288..2654485 Escherichia coli O104:H4 str. 2011C-3493 13702108 YP_006779290.1 CDS O3K_13000 NC_018658.1 2654560 2655321 D COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator YdeO 2654560..2655321 Escherichia coli O104:H4 str. 2011C-3493 13702109 YP_006779291.1 CDS O3K_13005 NC_018658.1 2655723 2657405 D COG3119 Arylsulfatase A and related enzymes; hypothetical protein 2655723..2657405 Escherichia coli O104:H4 str. 2011C-3493 13702110 YP_006779292.1 CDS O3K_13010 NC_018658.1 2657457 2658614 D COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); hypothetical protein 2657457..2658614 Escherichia coli O104:H4 str. 2011C-3493 13702111 YP_006779293.1 CDS O3K_13015 NC_018658.1 2658905 2660590 D permease and ATP-binding component; COG4178 ABC-type uncharacterized transport system, permease and ATPase components; multidrug ABC transporter 2658905..2660590 Escherichia coli O104:H4 str. 2011C-3493 13702112 YP_006779294.1 CDS O3K_13020 NC_018658.1 2660628 2663000 D COG1629 Outer membrane receptor proteins, mostly Fe transport; porin protein 2660628..2663000 Escherichia coli O104:H4 str. 2011C-3493 13702113 YP_006779295.1 CDS O3K_13025 NC_018658.1 2663045 2665840 D COG0612 Predicted Zn-dependent peptidases; membrane-associated peptidase 2663045..2665840 Escherichia coli O104:H4 str. 2011C-3493 13702114 YP_006779296.1 CDS O3K_13030 NC_018658.1 2666202 2667602 D COG0076 Glutamate decarboxylase and related PLP-dependent proteins; glutamate decarboxylase 2666202..2667602 Escherichia coli O104:H4 str. 2011C-3493 13702115 YP_006779297.1 CDS O3K_13035 NC_018658.1 2667758 2669293 D COG0531 Amino acid transporters; glutamate/gamma-aminobutyrate antiporter 2667758..2669293 Escherichia coli O104:H4 str. 2011C-3493 13702116 YP_006779298.1 CDS O3K_13040 NC_018658.1 2669424 2670743 D COG1649 Uncharacterized protein conserved in bacteria; lipoprotein 2669424..2670743 Escherichia coli O104:H4 str. 2011C-3493 13702117 YP_006779299.1 CDS O3K_13045 NC_018658.1 2671115 2672497 D COG2199 FOG: GGDEF domain; diguanylate cyclase 2671115..2672497 Escherichia coli O104:H4 str. 2011C-3493 13702118 YP_006779300.1 CDS O3K_13050 NC_018658.1 2672522 2674921 D COG2202 FOG: PAS/PAC domain; cyclic-di-GMP phosphodiesterase 2672522..2674921 Escherichia coli O104:H4 str. 2011C-3493 13702119 YP_006779301.1 CDS O3K_13055 NC_018658.1 2675179 2675760 D COG2173 D-alanyl-D-alanine dipeptidase; D-alanyl-D-alanine dipeptidase 2675179..2675760 Escherichia coli O104:H4 str. 2011C-3493 13702120 YP_006779302.1 CDS O3K_13060 NC_018658.1 2675774 2677324 D COG0747 ABC-type dipeptide transport system, periplasmic component; D-ala-D-a la ABC transporter substrate-binding protein 2675774..2677324 Escherichia coli O104:H4 str. 2011C-3493 13702121 YP_006779303.1 CDS O3K_13065 NC_018658.1 2677326 2678348 D COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transporter inner membrane component 2677326..2678348 Escherichia coli O104:H4 str. 2011C-3493 13702122 YP_006779304.1 CDS O3K_13070 NC_018658.1 2678345 2679241 D COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; D-ala-D-ala transporter subunit 2678345..2679241 Escherichia coli O104:H4 str. 2011C-3493 13702123 YP_006779305.1 CDS O3K_13075 NC_018658.1 2679238 2680224 D COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; D-ala-D-ala ABC transporter ATP-binding protein 2679238..2680224 Escherichia coli O104:H4 str. 2011C-3493 13702124 YP_006779306.1 CDS O3K_13080 NC_018658.1 2680217 2681143 D COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; D-ala-D-ala ABC transporter ATP-binding protein 2680217..2681143 Escherichia coli O104:H4 str. 2011C-3493 13702125 YP_006779307.1 CDS O3K_13085 NC_018658.1 2681199 2681630 R COG1764 Predicted redox protein, regulator of disulfide bond formation; osmotically inducible, stress-inducible membrane protein OsmC complement(2681199..2681630) Escherichia coli O104:H4 str. 2011C-3493 13702126 YP_006779308.1 CDS O3K_13090 NC_018658.1 2681976 2682191 D biofilm-dependent modulation protein 2681976..2682191 Escherichia coli O104:H4 str. 2011C-3493 13702127 YP_006779309.1 CDS rpsV NC_018658.1 2682293 2682430 D 30S ribosomal subunit S22 2682293..2682430 Escherichia coli O104:H4 str. 2011C-3493 13702128 YP_006779310.1 CDS O3K_13100 NC_018658.1 2682587 2684284 D COG0281 Malic enzyme; malate dehydrogenase 2682587..2684284 Escherichia coli O104:H4 str. 2011C-3493 13702129 YP_006779311.1 CDS O3K_13105 NC_018658.1 2684418 2685428 D COG1064 Zn-dependent alcohol dehydrogenases; ethanol-active dehydrogenase/acetaldehyde-active reductase 2684418..2685428 Escherichia coli O104:H4 str. 2011C-3493 13702130 YP_006779312.1 CDS O3K_13110 NC_018658.1 2685575 2685859 D COG3093 Plasmid maintenance system antidote protein; putative DNA-binding transcriptional regulator 2685575..2685859 Escherichia coli O104:H4 str. 2011C-3493 13702131 YP_006779313.1 CDS O3K_13115 NC_018658.1 2685910 2686563 R COG2864 Cytochrome b subunit of formate dehydrogenase; formate dehydrogenase-N subunit gamma complement(2685910..2686563) Escherichia coli O104:H4 str. 2011C-3493 13702132 YP_006779314.1 CDS O3K_13120 NC_018658.1 2686556 2687440 R COG0437 Fe-S-cluster-containing hydrogenase components 1; formate dehydrogenase, nitrate-inducible, iron-sulfur subunit complement(2686556..2687440) Escherichia coli O104:H4 str. 2011C-3493 13702133 YP_006779315.1 CDS O3K_13135 NC_018658.1 2690732 2691613 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; aromatic amino acid exporter 2690732..2691613 Escherichia coli O104:H4 str. 2011C-3493 13702134 YP_006779316.1 CDS O3K_13140 NC_018658.1 2691872 2692162 D COG3203 Outer membrane protein (porin); lipoprotein 2691872..2692162 Escherichia coli O104:H4 str. 2011C-3493 13702135 YP_006779317.1 CDS O3K_13145 NC_018658.1 2692186 2693517 D COG4886 Leucine-rich repeat (LRR) protein; glycoprotein with ribonuclease inhibitor domain (yddK, modular protein) 2692186..2693517 Escherichia coli O104:H4 str. 2011C-3493 13702136 YP_006779318.1 CDS O3K_13150 NC_018658.1 2693841 2695229 D COG2223 Nitrate/nitrite transporter; nitrate/nitrite transport protein NarU 2693841..2695229 Escherichia coli O104:H4 str. 2011C-3493 13702137 YP_006779319.1 CDS O3K_13155 NC_018658.1 2695311 2699051 D COG5013 Nitrate reductase alpha subunit; nitrate reductase 2 subunit alpha 2695311..2699051 Escherichia coli O104:H4 str. 2011C-3493 13702138 YP_006779320.1 CDS O3K_13160 NC_018658.1 2699048 2700592 D COG1140 Nitrate reductase beta subunit; nitrate reductase 2 (NRZ) subunit beta 2699048..2700592 Escherichia coli O104:H4 str. 2011C-3493 13702139 YP_006779321.1 CDS O3K_13165 NC_018658.1 2700592 2701287 D COG2180 Nitrate reductase delta subunit; nitrate reductase 2 subunit delta 2700592..2701287 Escherichia coli O104:H4 str. 2011C-3493 13702140 YP_006779322.1 CDS O3K_13170 NC_018658.1 2701284 2701964 D COG2181 Nitrate reductase gamma subunit; nitrate reductase 2 (NRZ) subunit gamma 2701284..2701964 Escherichia coli O104:H4 str. 2011C-3493 13702141 YP_006779323.1 CDS O3K_13175 NC_018658.1 2702043 2702936 D COG0384 Predicted epimerase, PhzC/PhzF homolog; hypothetical protein 2702043..2702936 Escherichia coli O104:H4 str. 2011C-3493 13702142 YP_006779324.1 CDS O3K_13180 NC_018658.1 2703032 2703877 R COG2162 Arylamine N-acetyltransferase; N-hydroxyarylamine O-acetyltransferase complement(2703032..2703877) Escherichia coli O104:H4 str. 2011C-3493 13702143 YP_006779325.1 CDS O3K_13185 NC_018658.1 2704050 2704619 D COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein 2704050..2704619 Escherichia coli O104:H4 str. 2011C-3493 13702144 YP_006779326.1 CDS O3K_13190 NC_018658.1 2704623 2704850 R COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; 4-oxalocrotonate tautomerase complement(2704623..2704850) Escherichia coli O104:H4 str. 2011C-3493 13702145 YP_006779327.1 CDS O3K_13195 NC_018658.1 2704883 2705581 R COG5433 Transposase; H repeat-associated protein complement(2704883..2705581) Escherichia coli O104:H4 str. 2011C-3493 13702146 YP_006779328.1 CDS O3K_13200 NC_018658.1 2705935 2706384 R hypothetical protein complement(2705935..2706384) Escherichia coli O104:H4 str. 2011C-3493 13702147 YP_006779329.1 CDS O3K_13205 NC_018658.1 2706396 2710637 R COG3209 Rhs family protein; rhsD element protein complement(2706396..2710637) Escherichia coli O104:H4 str. 2011C-3493 13702148 YP_006779330.1 CDS O3K_13210 NC_018658.1 2710705 2712813 R Encoded within repeats that are hotspots for chromosomal duplication formation; COG3501 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2710705..2712813) Escherichia coli O104:H4 str. 2011C-3493 13702149 YP_006779331.1 CDS O3K_13215 NC_018658.1 2713633 2713845 R hypothetical protein complement(2713633..2713845) Escherichia coli O104:H4 str. 2011C-3493 13702150 YP_006779332.1 CDS O3K_13220 NC_018658.1 2713921 2714538 R COG0625 Glutathione S-transferase; glutathione S-transferase-like protein complement(2713921..2714538) Escherichia coli O104:H4 str. 2011C-3493 13702151 YP_006779333.1 CDS O3K_13225 NC_018658.1 2714805 2716304 D COG1113 Gamma-aminobutyrate permease and related permeases; L-asparagine permease 2714805..2716304 Escherichia coli O104:H4 str. 2011C-3493 13702152 YP_006779334.1 CDS O3K_13230 NC_018658.1 2716417 2717478 R COG3391 Uncharacterized conserved protein; hypothetical protein complement(2716417..2717478) Escherichia coli O104:H4 str. 2011C-3493 13702153 YP_006779335.1 CDS O3K_13235 NC_018658.1 2717720 2719822 D COG1629 Outer membrane receptor proteins, mostly Fe transport; iron outer membrane receptor 2717720..2719822 Escherichia coli O104:H4 str. 2011C-3493 13702154 YP_006779336.1 CDS O3K_13240 NC_018658.1 2719858 2720523 R COG1802 Transcriptional regulators; colanic acid/biofilm transcriptional regulator complement(2719858..2720523) Escherichia coli O104:H4 str. 2011C-3493 13702155 YP_006779337.1 CDS O3K_13245 NC_018658.1 2720721 2721758 R COG2130 Putative NADP-dependent oxidoreductases; oxidoreductase complement(2720721..2721758) Escherichia coli O104:H4 str. 2011C-3493 13702156 YP_006779338.1 CDS O3K_13250 NC_018658.1 2721939 2722457 D COG1247 Sortase and related acyltransferases; acyl-CoA N-acyltransferase 2721939..2722457 Escherichia coli O104:H4 str. 2011C-3493 13702157 YP_006779339.1 CDS O3K_13255 NC_018658.1 2722454 2722903 D COG3238 Uncharacterized protein conserved in bacteria; inner membrane protein 2722454..2722903 Escherichia coli O104:H4 str. 2011C-3493 13702158 YP_006779340.1 CDS O3K_13260 NC_018658.1 2722904 2723137 R hypothetical protein complement(2722904..2723137) Escherichia coli O104:H4 str. 2011C-3493 13702159 YP_006779341.1 CDS O3K_13265 NC_018658.1 2723223 2723396 R hypothetical protein complement(2723223..2723396) Escherichia coli O104:H4 str. 2011C-3493 13702160 YP_006779342.1 CDS O3K_13270 NC_018658.1 2724088 2724897 R COG0110 Acetyltransferase (isoleucine patch superfamily); acetyltransferase complement(2724088..2724897) Escherichia coli O104:H4 str. 2011C-3493 13702161 YP_006779343.1 CDS O3K_13275 NC_018658.1 2725107 2726531 R COG1012 NAD-dependent aldehyde dehydrogenases; gamma-aminobutyraldehyde dehydrogenase complement(2725107..2726531) Escherichia coli O104:H4 str. 2011C-3493 13702162 YP_006779344.1 CDS O3K_13280 NC_018658.1 2726553 2727347 R COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease complement(2726553..2727347) Escherichia coli O104:H4 str. 2011C-3493 13702163 YP_006779345.1 CDS O3K_13285 NC_018658.1 2727337 2728278 R COG1176 ABC-type spermidine/putrescine transport system, permease component I; ABC transporter permease complement(2727337..2728278) Escherichia coli O104:H4 str. 2011C-3493 13702164 YP_006779346.1 CDS O3K_13290 NC_018658.1 2728279 2729292 R COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATP-binding protein complement(2728279..2729292) Escherichia coli O104:H4 str. 2011C-3493 13702165 YP_006779347.1 CDS O3K_13295 NC_018658.1 2729310 2730455 R COG0687 Spermidine/putrescine-binding periplasmic protein; putative spermidine/putrescine transporter subunit complement(2729310..2730455) Escherichia coli O104:H4 str. 2011C-3493 13702166 YP_006779348.1 CDS O3K_13300 NC_018658.1 2730700 2732106 R transcriptional regulator, GntR family; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator complement(2730700..2732106) Escherichia coli O104:H4 str. 2011C-3493 13702167 YP_006779349.1 CDS O3K_13305 NC_018658.1 2732185 2732622 R COG1598 Uncharacterized conserved protein; DNA-binding transcriptional regulator complement(2732185..2732622) Escherichia coli O104:H4 str. 2011C-3493 13702168 YP_006779350.1 CDS O3K_13310 NC_018658.1 2733023 2733253 D hypothetical protein 2733023..2733253 Escherichia coli O104:H4 str. 2011C-3493 13702239 YP_006779351.1 CDS O3K_13315 NC_018658.1 2733345 2735306 R COG0826 Collagenase and related proteases; peptidase, U32 family protein complement(2733345..2735306) Escherichia coli O104:H4 str. 2011C-3493 13702240 YP_006779352.1 CDS O3K_13320 NC_018658.1 2735379 2735915 R COG1396 Predicted transcriptional regulators; putative DNA-binding transcriptional regulator complement(2735379..2735915) Escherichia coli O104:H4 str. 2011C-3493 13702241 YP_006779353.1 CDS O3K_13325 NC_018658.1 2736007 2737182 D COG3135 Uncharacterized protein involved in benzoate metabolism; putative benzoate transporter 2736007..2737182 Escherichia coli O104:H4 str. 2011C-3493 13702242 YP_006779354.1 CDS O3K_13330 NC_018658.1 2737222 2738430 R COG0675 Transposase and inactivated derivatives; transposase complement(2737222..2738430) Escherichia coli O104:H4 str. 2011C-3493 13702243 YP_006779355.1 CDS O3K_13345 NC_018658.1 2738957 2739625 R hypothetical protein complement(2738957..2739625) Escherichia coli O104:H4 str. 2011C-3493 13702244 YP_006779356.1 CDS O3K_13350 NC_018658.1 2739928 2740521 R COG0500 SAM-dependent methyltransferases; tellurite resistance protein TehB complement(2739928..2740521) Escherichia coli O104:H4 str. 2011C-3493 13702245 YP_006779357.1 CDS O3K_13355 NC_018658.1 2740518 2741510 R COG1275 Tellurite resistance protein and related permeases; potassium-tellurite ethidium and proflavin transporter complement(2740518..2741510) Escherichia coli O104:H4 str. 2011C-3493 13702246 YP_006779358.1 CDS O3K_13360 NC_018658.1 2741634 2742614 D COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; hypothetical protein 2741634..2742614 Escherichia coli O104:H4 str. 2011C-3493 13702247 YP_006779359.1 CDS O3K_13365 NC_018658.1 2742609 2743145 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-L7/L12-serine acetyltransferase complement(2742609..2743145) Escherichia coli O104:H4 str. 2011C-3493 13702248 YP_006779360.1 CDS O3K_13370 NC_018658.1 2743208 2743432 R COG2841 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2743208..2743432) Escherichia coli O104:H4 str. 2011C-3493 13702249 YP_006779361.1 CDS O3K_13375 NC_018658.1 2743448 2743651 D hypothetical protein 2743448..2743651 Escherichia coli O104:H4 str. 2011C-3493 13702250 YP_006779362.1 CDS mdoD NC_018658.1 2743572 2745227 R COG3131 Periplasmic glucans biosynthesis protein; glucan biosynthesis protein D complement(2743572..2745227) Escherichia coli O104:H4 str. 2011C-3493 13702251 YP_006779363.1 CDS O3K_13385 NC_018658.1 2745452 2746795 R COG5383 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2745452..2746795) Escherichia coli O104:H4 str. 2011C-3493 13702252 YP_006779364.1 CDS O3K_13390 NC_018658.1 2747012 2747935 D COG0583 Transcriptional regulator; transcriptional regulator 2747012..2747935 Escherichia coli O104:H4 str. 2011C-3493 13702253 YP_006779365.1 CDS O3K_13395 NC_018658.1 2747973 2749613 R COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor complement(2747973..2749613) Escherichia coli O104:H4 str. 2011C-3493 13702254 YP_006779366.1 CDS O3K_13400 NC_018658.1 2750012 2750161 D small toxic polypeptide 2750012..2750161 Escherichia coli O104:H4 str. 2011C-3493 13702255 YP_006779367.1 CDS O3K_13405 NC_018658.1 2750233 2750406 R hypothetical protein complement(2750233..2750406) Escherichia coli O104:H4 str. 2011C-3493 13702256 YP_006779368.1 CDS O3K_13410 NC_018658.1 2750651 2751181 R COG3038 Cytochrome B561; cytochrome b561 complement(2750651..2751181) Escherichia coli O104:H4 str. 2011C-3493 13702257 YP_006779369.1 CDS O3K_13415 NC_018658.1 2751370 2752371 D COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2751370..2752371 Escherichia coli O104:H4 str. 2011C-3493 13702258 YP_006779370.1 CDS O3K_13420 NC_018658.1 2752413 2753852 R COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase A complement(2752413..2753852) Escherichia coli O104:H4 str. 2011C-3493 13702259 YP_006779371.1 CDS O3K_13425 NC_018658.1 2754049 2754849 R COG1434 Uncharacterized conserved protein; hypothetical protein complement(2754049..2754849) Escherichia coli O104:H4 str. 2011C-3493 13702260 YP_006779372.1 CDS O3K_13430 NC_018658.1 2755121 2758966 R COG1643 HrpA-like helicases; ATP-dependent RNA helicase HrpA complement(2755121..2758966) Escherichia coli O104:H4 str. 2011C-3493 13702261 YP_006779373.1 CDS O3K_13435 NC_018658.1 2759224 2759829 D COG1182 Acyl carrier protein phosphodiesterase; azoreductase 2759224..2759829 Escherichia coli O104:H4 str. 2011C-3493 13702262 YP_006779374.1 CDS O3K_13440 NC_018658.1 2759880 2761172 R COG0671 Membrane-associated phospholipid phosphatase; membrane associated phosphatase complement(2759880..2761172) Escherichia coli O104:H4 str. 2011C-3493 13702263 YP_006779375.1 CDS O3K_13445 NC_018658.1 2761186 2762943 R COG2267 Lysophospholipase; hydrolase complement(2761186..2762943) Escherichia coli O104:H4 str. 2011C-3493 13702264 YP_006779376.1 CDS O3K_13450 NC_018658.1 2762959 2763855 R COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; membrane associated CTP-phosphosubstrate transferase complement(2762959..2763855) Escherichia coli O104:H4 str. 2011C-3493 13702265 YP_006779377.1 CDS O3K_13455 NC_018658.1 2763855 2764460 R COG0558 Phosphatidylglycerophosphate synthase; inner membrane protein complement(2763855..2764460) Escherichia coli O104:H4 str. 2011C-3493 13702266 YP_006779378.1 CDS O3K_13460 NC_018658.1 2764631 2766937 R hypothetical protein complement(2764631..2766937) Escherichia coli O104:H4 str. 2011C-3493 13702267 YP_006779379.1 CDS O3K_13465 NC_018658.1 2767001 2767861 R COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase complement(2767001..2767861) Escherichia coli O104:H4 str. 2011C-3493 13702268 YP_006779380.1 CDS O3K_13470 NC_018658.1 2768091 2768681 R COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; hexapeptide repeat acetyltransferase complement(2768091..2768681) Escherichia coli O104:H4 str. 2011C-3493 13702269 YP_006779381.1 CDS O3K_13475 NC_018658.1 2768663 2769613 R COG3327 Phenylacetic acid-responsive transcriptional repressor; DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive complement(2768663..2769613) Escherichia coli O104:H4 str. 2011C-3493 13702270 YP_006779382.1 CDS O3K_13480 NC_018658.1 2769714 2771027 R COG1541 Coenzyme F390 synthetase; phenylacetate-CoA ligase complement(2769714..2771027) Escherichia coli O104:H4 str. 2011C-3493 13702271 YP_006779383.1 CDS O3K_13485 NC_018658.1 2771054 2772259 R COG0183 Acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase complement(2771054..2772259) Escherichia coli O104:H4 str. 2011C-3493 13702272 YP_006779384.1 CDS O3K_13490 NC_018658.1 2772259 2772681 R COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; thioesterase complement(2772259..2772681) Escherichia coli O104:H4 str. 2011C-3493 13702273 YP_006779385.1 CDS O3K_13495 NC_018658.1 2772671 2774098 R COG1250 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase complement(2772671..2774098) Escherichia coli O104:H4 str. 2011C-3493 13702274 YP_006779386.1 CDS O3K_13500 NC_018658.1 2774100 2774888 R COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase complement(2774100..2774888) Escherichia coli O104:H4 str. 2011C-3493 13702275 YP_006779387.1 CDS O3K_13505 NC_018658.1 2774888 2775655 R COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase-isomerase complement(2774888..2775655) Escherichia coli O104:H4 str. 2011C-3493 13702276 YP_006779388.1 CDS O3K_13510 NC_018658.1 2775652 2776722 R COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; subunit of the phenylacetly-CoA oxygenase/reductase complement(2775652..2776722) Escherichia coli O104:H4 str. 2011C-3493 13702277 YP_006779389.1 CDS O3K_13515 NC_018658.1 2776730 2777227 R COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; putative multicomponent oxygenase/reductase subunit complement(2776730..2777227) Escherichia coli O104:H4 str. 2011C-3493 13702278 YP_006779390.1 CDS O3K_13520 NC_018658.1 2777242 2777988 R COG3396 Uncharacterized conserved protein; putative multicomponent oxygenase/reductase subunit complement(2777242..2777988) Escherichia coli O104:H4 str. 2011C-3493 13702279 YP_006779391.1 CDS paaB NC_018658.1 2777997 2778284 R COG3460 Uncharacterized enzyme of phenylacetate metabolism; phenylacetate-CoA oxygenase subunit PaaB complement(2777997..2778284) Escherichia coli O104:H4 str. 2011C-3493 13702280 YP_006779392.1 CDS paaA NC_018658.1 2778296 2779225 R COG3396 Uncharacterized conserved protein; phenylacetate-CoA oxygenase subunit PaaA complement(2778296..2779225) Escherichia coli O104:H4 str. 2011C-3493 13702281 YP_006779393.1 CDS O3K_13535 NC_018658.1 2779510 2781555 D COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 2779510..2781555 Escherichia coli O104:H4 str. 2011C-3493 13702282 YP_006779394.1 CDS tynA NC_018658.1 2781803 2784076 D COG3733 Cu2+-containing amine oxidase; tyramine oxidase 2781803..2784076 Escherichia coli O104:H4 str. 2011C-3493 13702283 YP_006779395.1 CDS O3K_13545 NC_018658.1 2784134 2785633 R COG1012 NAD-dependent aldehyde dehydrogenases; phenylacetaldehyde dehydrogenase complement(2784134..2785633) Escherichia coli O104:H4 str. 2011C-3493 13702284 YP_006779396.1 CDS O3K_13550 NC_018658.1 2785869 2786774 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator FeaR 2785869..2786774 Escherichia coli O104:H4 str. 2011C-3493 13702285 YP_006779397.1 CDS O3K_13555 NC_018658.1 2786946 2787272 R COG3784 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2786946..2787272) Escherichia coli O104:H4 str. 2011C-3493 13702286 YP_006779398.1 CDS O3K_13560 NC_018658.1 2787280 2787465 R lipoprotein complement(2787280..2787465) Escherichia coli O104:H4 str. 2011C-3493 13702287 YP_006779399.1 CDS O3K_13565 NC_018658.1 2787462 2790101 R hypothetical protein complement(2787462..2790101) Escherichia coli O104:H4 str. 2011C-3493 13702288 YP_006779400.1 CDS O3K_13570 NC_018658.1 2790309 2791298 D COG1052 Lactate dehydrogenase and related dehydrogenases; D-lactate dehydrogenase 2790309..2791298 Escherichia coli O104:H4 str. 2011C-3493 13702289 YP_006779401.1 CDS O3K_13575 NC_018658.1 2791409 2791831 D COG3187 Heat shock protein; heat-inducible protein 2791409..2791831 Escherichia coli O104:H4 str. 2011C-3493 13702290 YP_006779402.1 CDS O3K_13580 NC_018658.1 2791828 2792094 R COG3042 Putative hemolysin; hypothetical protein complement(2791828..2792094) Escherichia coli O104:H4 str. 2011C-3493 13702291 YP_006779403.1 CDS O3K_13585 NC_018658.1 2792368 2795892 D COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; 2-oxoacid-flavodoxin oxidoreductase 2792368..2795892 Escherichia coli O104:H4 str. 2011C-3493 13702292 YP_006779404.1 CDS O3K_13590 NC_018658.1 2796259 2797392 D COG3203 Outer membrane protein (porin); outer membrane pore protein N, non-specific 2796259..2797392 Escherichia coli O104:H4 str. 2011C-3493 13702293 YP_006779405.1 CDS O3K_13595 NC_018658.1 2797533 2797967 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein F 2797533..2797967 Escherichia coli O104:H4 str. 2011C-3493 13702294 YP_006779406.1 CDS O3K_13600 NC_018658.1 2798143 2799078 D COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA 2-thiocytidine biosynthesis protein TtcA 2798143..2799078 Escherichia coli O104:H4 str. 2011C-3493 13702295 YP_006779407.1 CDS O3K_13605 NC_018658.1 2799207 2800580 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase DbpA complement(2799207..2800580) Escherichia coli O104:H4 str. 2011C-3493 13702296 YP_006779408.1 CDS O3K_13610 NC_018658.1 2800610 2800783 R hypothetical protein complement(2800610..2800783) Escherichia coli O104:H4 str. 2011C-3493 13702297 YP_006779409.1 CDS zntB NC_018658.1 2801058 2802041 R COG0598 Mg2+ and Co2+ transporters; zinc transporter complement(2801058..2802041) Escherichia coli O104:H4 str. 2011C-3493 13702298 YP_006779410.1 CDS O3K_13620 NC_018658.1 2802296 2803528 D COG2199 FOG: GGDEF domain; hypothetical protein 2802296..2803528 Escherichia coli O104:H4 str. 2011C-3493 13702299 YP_006779411.1 CDS O3K_13625 NC_018658.1 2803549 2804112 R COG2840 Uncharacterized protein conserved in bacteria; Smr domain-containing protein complement(2803549..2804112) Escherichia coli O104:H4 str. 2011C-3493 13702300 YP_006779412.1 CDS O3K_13630 NC_018658.1 2804442 2805350 R COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator complement(2804442..2805350) Escherichia coli O104:H4 str. 2011C-3493 13702301 YP_006779413.1 CDS O3K_13635 NC_018658.1 2805526 2806836 D COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; putative peptidase, aminobenzoyl-glutamate utilization protein AbgA 2805526..2806836 Escherichia coli O104:H4 str. 2011C-3493 13702302 YP_006779414.1 CDS O3K_13640 NC_018658.1 2806836 2808281 D COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; peptidase, aminobenzoyl-glutamate utilization protein AbgB 2806836..2808281 Escherichia coli O104:H4 str. 2011C-3493 13702303 YP_006779415.1 CDS abgT NC_018658.1 2808318 2809844 D COG2978 Putative p-aminobenzoyl-glutamate transporter; putative aminobenzoyl-glutamate transporter 2808318..2809844 Escherichia coli O104:H4 str. 2011C-3493 13702304 YP_006779416.1 CDS O3K_13650 NC_018658.1 2809855 2810370 D COG0350 Methylated DNA-protein cysteine methyltransferase; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 2809855..2810370 Escherichia coli O104:H4 str. 2011C-3493 13702305 YP_006779417.1 CDS O3K_13655 NC_018658.1 2810565 2811317 D COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; fumarate/nitrate reduction transcriptional regulator 2810565..2811317 Escherichia coli O104:H4 str. 2011C-3493 13702306 YP_006779418.1 CDS O3K_13660 NC_018658.1 2811469 2812419 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspE 2811469..2812419 Escherichia coli O104:H4 str. 2011C-3493 13702377 YP_006779419.1 CDS O3K_13665 NC_018658.1 2812469 2812726 R hypothetical protein complement(2812469..2812726) Escherichia coli O104:H4 str. 2011C-3493 13702378 YP_006779420.1 CDS O3K_13670 NC_018658.1 2812970 2814001 D COG0668 Small-conductance mechanosensitive channel; MscS family inner membrane protein YnaI 2812970..2814001 Escherichia coli O104:H4 str. 2011C-3493 13702379 YP_006779421.1 CDS O3K_13675 NC_018658.1 2814052 2815665 R COG4166 ABC-type oligopeptide transport system, periplasmic component; transport periplasmic protein complement(2814052..2815665) Escherichia coli O104:H4 str. 2011C-3493 13702380 YP_006779422.1 CDS O3K_13680 NC_018658.1 2815788 2815913 R hypothetical protein complement(2815788..2815913) Escherichia coli O104:H4 str. 2011C-3493 13702381 YP_006779423.1 CDS O3K_13685 NC_018658.1 2816002 2816901 R COG0583 Transcriptional regulator; LysR family transcriptional regulator complement(2816002..2816901) Escherichia coli O104:H4 str. 2011C-3493 13702382 YP_006779424.1 CDS O3K_13690 NC_018658.1 2817027 2817959 D COG1073 Hydrolases of the alpha/beta superfamily; hydrolase 2817027..2817959 Escherichia coli O104:H4 str. 2011C-3493 13702383 YP_006779425.1 CDS O3K_13695 NC_018658.1 2818030 2818194 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 2818030..2818194 Escherichia coli O104:H4 str. 2011C-3493 13702384 YP_006779426.1 CDS O3K_13700 NC_018658.1 2818295 2819023 D COG2866 Predicted carboxypeptidase; murein peptide amidase A 2818295..2819023 Escherichia coli O104:H4 str. 2011C-3493 13702385 YP_006779427.1 CDS O3K_13705 NC_018658.1 2818998 2819963 R COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; L-Ala-D/L-Glu epimerase complement(2818998..2819963) Escherichia coli O104:H4 str. 2011C-3493 13702386 YP_006779428.1 CDS tpx NC_018658.1 2820082 2820588 D COG2077 Peroxiredoxin; lipid hydroperoxide peroxidase 2820082..2820588 Escherichia coli O104:H4 str. 2011C-3493 13702387 YP_006779429.1 CDS O3K_13715 NC_018658.1 2820632 2822173 R COG3283 Transcriptional regulator of aromatic amino acids metabolism; DNA-binding transcriptional regulator TyrR complement(2820632..2822173) Escherichia coli O104:H4 str. 2011C-3493 13702388 YP_006779430.1 CDS O3K_13720 NC_018658.1 2822321 2823382 R COG3768 Predicted membrane protein; hypothetical protein complement(2822321..2823382) Escherichia coli O104:H4 str. 2011C-3493 13702389 YP_006779431.1 CDS O3K_13725 NC_018658.1 2823379 2824776 R COG3106 Predicted ATPase; hypothetical protein complement(2823379..2824776) Escherichia coli O104:H4 str. 2011C-3493 13702390 YP_006779432.1 CDS O3K_13730 NC_018658.1 2824931 2825929 D COG1609 Transcriptional regulators; DNA-binding transcriptional regulator 2824931..2825929 Escherichia coli O104:H4 str. 2011C-3493 13702391 YP_006779433.1 CDS O3K_13735 NC_018658.1 2826040 2826945 R outer membrane porin complement(2826040..2826945) Escherichia coli O104:H4 str. 2011C-3493 13702392 YP_006779434.1 CDS O3K_13740 NC_018658.1 2826990 2828072 R COG3839 ABC-type sugar transport systems, ATPase components; sugar transporter subunit complement(2826990..2828072) Escherichia coli O104:H4 str. 2011C-3493 13702393 YP_006779435.1 CDS O3K_13745 NC_018658.1 2828086 2828745 R COG0637 Predicted phosphatase/phosphohexomutase; putative beta-phosphoglucomutase complement(2828086..2828745) Escherichia coli O104:H4 str. 2011C-3493 13702394 YP_006779436.1 CDS O3K_13750 NC_018658.1 2828742 2831009 R COG1554 Trehalose and maltose hydrolases (possible phosphorylases); hydrolase complement(2828742..2831009) Escherichia coli O104:H4 str. 2011C-3493 13702395 YP_006779437.1 CDS O3K_13755 NC_018658.1 2831006 2832061 R COG0673 Predicted dehydrogenases and related proteins; oxidoreductase complement(2831006..2832061) Escherichia coli O104:H4 str. 2011C-3493 13702396 YP_006779438.1 CDS O3K_13760 NC_018658.1 2832071 2832859 R COG1082 Sugar phosphate isomerases/epimerases; hypothetical protein complement(2832071..2832859) Escherichia coli O104:H4 str. 2011C-3493 13702397 YP_006779439.1 CDS O3K_13765 NC_018658.1 2832877 2833929 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein complement(2832877..2833929) Escherichia coli O104:H4 str. 2011C-3493 13702398 YP_006779440.1 CDS O3K_13770 NC_018658.1 2833960 2834802 R COG0395 ABC-type sugar transport system, permease component; putative sugar transporter subunit complement(2833960..2834802) Escherichia coli O104:H4 str. 2011C-3493 13702399 YP_006779441.1 CDS O3K_13775 NC_018658.1 2834789 2835670 R COG1175 ABC-type sugar transport systems, permease components; putative sugar transporter subunit complement(2834789..2835670) Escherichia coli O104:H4 str. 2011C-3493 13702400 YP_006779442.1 CDS O3K_13780 NC_018658.1 2835691 2836983 R COG1653 ABC-type sugar transport system, periplasmic component; putative sugar transporter subunit complement(2835691..2836983) Escherichia coli O104:H4 str. 2011C-3493 13702401 YP_006779443.1 CDS O3K_13785 NC_018658.1 2836997 2838676 R COG0366 Glycosidases; putative glucosyltransferase complement(2836997..2838676) Escherichia coli O104:H4 str. 2011C-3493 13702402 YP_006779444.1 CDS O3K_13790 NC_018658.1 2838889 2839203 R COG0607 Rhodanese-related sulfurtransferase; thiosulfate:cyanide sulfurtransferase complement(2838889..2839203) Escherichia coli O104:H4 str. 2011C-3493 13702403 YP_006779445.1 CDS O3K_13795 NC_018658.1 2839278 2839499 R peripheral inner membrane phage-shock protein complement(2839278..2839499) Escherichia coli O104:H4 str. 2011C-3493 13702404 YP_006779446.1 CDS O3K_13800 NC_018658.1 2839508 2839867 R COG1983 Putative stress-responsive transcriptional regulator; DNA-binding transcriptional activator PspC complement(2839508..2839867) Escherichia coli O104:H4 str. 2011C-3493 13702405 YP_006779447.1 CDS pspB NC_018658.1 2839867 2840091 R phage shock protein B complement(2839867..2840091) Escherichia coli O104:H4 str. 2011C-3493 13702406 YP_006779448.1 CDS O3K_13810 NC_018658.1 2840145 2840813 R COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription; phage shock protein PspA complement(2840145..2840813) Escherichia coli O104:H4 str. 2011C-3493 13702407 YP_006779449.1 CDS pspF NC_018658.1 2840980 2841957 D COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain; phage shock protein operon transcriptional activator 2840980..2841957 Escherichia coli O104:H4 str. 2011C-3493 13702408 YP_006779450.1 CDS O3K_13820 NC_018658.1 2842077 2843342 R COG0160 4-aminobutyrate aminotransferase and related aminotransferases; 4-aminobutyrate transaminase complement(2842077..2843342) Escherichia coli O104:H4 str. 2011C-3493 13702409 YP_006779451.1 CDS O3K_13825 NC_018658.1 2843380 2844660 R COG0665 Glycine/D-amino acid oxidases (deaminating); gamma-Glu-putrescine oxidase complement(2843380..2844660) Escherichia coli O104:H4 str. 2011C-3493 13702410 YP_006779452.1 CDS O3K_13830 NC_018658.1 2844662 2846149 R COG1012 NAD-dependent aldehyde dehydrogenases; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase complement(2844662..2846149) Escherichia coli O104:H4 str. 2011C-3493 13702411 YP_006779453.1 CDS O3K_13835 NC_018658.1 2846424 2846981 R COG1396 Predicted transcriptional regulators; DNA-binding transcriptional repressor PuuR complement(2846424..2846981) Escherichia coli O104:H4 str. 2011C-3493 13702412 YP_006779454.1 CDS puuD NC_018658.1 2847008 2847772 R COG2071 Predicted glutamine amidotransferases; gamma-glutamyl-gamma-aminobutyrate hydrolase complement(2847008..2847772) Escherichia coli O104:H4 str. 2011C-3493 13702413 YP_006779455.1 CDS O3K_13845 NC_018658.1 2847984 2849402 D COG0174 Glutamine synthetase; gamma-glutamylputrescine synthetase 2847984..2849402 Escherichia coli O104:H4 str. 2011C-3493 13702414 YP_006779456.1 CDS O3K_13850 NC_018658.1 2849705 2851090 D COG0531 Amino acid transporters; putrescine importer 2849705..2851090 Escherichia coli O104:H4 str. 2011C-3493 13702415 YP_006779457.1 CDS O3K_13855 NC_018658.1 2851224 2851469 D hypothetical protein 2851224..2851469 Escherichia coli O104:H4 str. 2011C-3493 13702416 YP_006779458.1 CDS O3K_13860 NC_018658.1 2851781 2853424 D COG4166 ABC-type oligopeptide transport system, periplasmic component; antimicrobial peptide ABC transporter substrate-binding protein SapA 2851781..2853424 Escherichia coli O104:H4 str. 2011C-3493 13702417 YP_006779459.1 CDS O3K_13865 NC_018658.1 2853421 2854386 D COG4168 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease SapB 2853421..2854386 Escherichia coli O104:H4 str. 2011C-3493 13702418 YP_006779460.1 CDS O3K_13870 NC_018658.1 2854373 2855263 D COG4171 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease SapC 2854373..2855263 Escherichia coli O104:H4 str. 2011C-3493 13702419 YP_006779461.1 CDS O3K_13875 NC_018658.1 2855263 2856255 D COG4170 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATP-binding protein 2855263..2856255 Escherichia coli O104:H4 str. 2011C-3493 13702420 YP_006779462.1 CDS O3K_13880 NC_018658.1 2856257 2857063 D COG4167 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATP-binding protein SapF 2856257..2857063 Escherichia coli O104:H4 str. 2011C-3493 13702421 YP_006779463.1 CDS O3K_13885 NC_018658.1 2857131 2857484 D COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 2857131..2857484 Escherichia coli O104:H4 str. 2011C-3493 13702422 YP_006779464.1 CDS O3K_13890 NC_018658.1 2857854 2858642 D COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); enoyl-ACP reductase 2857854..2858642 Escherichia coli O104:H4 str. 2011C-3493 13702423 YP_006779465.1 CDS O3K_13895 NC_018658.1 2858787 2859914 D COG2128 Uncharacterized conserved protein; oxidoreductase 2858787..2859914 Escherichia coli O104:H4 str. 2011C-3493 13702424 YP_006779466.1 CDS O3K_13900 NC_018658.1 2859982 2861916 D COG4776 Exoribonuclease II; exoribonuclease II 2859982..2861916 Escherichia coli O104:H4 str. 2011C-3493 13702425 YP_006779467.1 CDS O3K_13905 NC_018658.1 2861994 2862098 R hypothetical protein complement(2861994..2862098) Escherichia coli O104:H4 str. 2011C-3493 13702426 YP_006779468.1 CDS O3K_13910 NC_018658.1 2862152 2864137 D COG2199 FOG: GGDEF domain; RNase II stability modulator 2862152..2864137 Escherichia coli O104:H4 str. 2011C-3493 13702427 YP_006779469.1 CDS O3K_13915 NC_018658.1 2864284 2864457 D hypothetical protein 2864284..2864457 Escherichia coli O104:H4 str. 2011C-3493 13702428 YP_006779470.1 CDS O3K_13920 NC_018658.1 2864547 2865296 D COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptionel regulator 2864547..2865296 Escherichia coli O104:H4 str. 2011C-3493 13702429 YP_006779471.1 CDS O3K_13925 NC_018658.1 2865565 2865783 D lipoprotein 2865565..2865783 Escherichia coli O104:H4 str. 2011C-3493 13702430 YP_006779472.1 CDS O3K_13930 NC_018658.1 2865909 2866235 R COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins; translation initiation factor Sui1 complement(2865909..2866235) Escherichia coli O104:H4 str. 2011C-3493 13702431 YP_006779473.1 CDS O3K_13935 NC_018658.1 2866235 2866972 R COG0284 Orotidine-5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase complement(2866235..2866972) Escherichia coli O104:H4 str. 2011C-3493 13702432 YP_006779474.1 CDS O3K_13940 NC_018658.1 2867165 2868334 R COG2956 Predicted N-acetylglucosaminyl transferase; hypothetical protein complement(2867165..2868334) Escherichia coli O104:H4 str. 2011C-3493 13702433 YP_006779475.1 CDS O3K_13945 NC_018658.1 2868341 2868649 R COG3771 Predicted membrane protein; hypothetical protein complement(2868341..2868649) Escherichia coli O104:H4 str. 2011C-3493 13702434 YP_006779476.1 CDS O3K_13950 NC_018658.1 2868798 2869562 R COG0671 Membrane-associated phospholipid phosphatase; phosphatidylglycerophosphatase B complement(2868798..2869562) Escherichia coli O104:H4 str. 2011C-3493 13702435 YP_006779477.1 CDS ribA NC_018658.1 2869732 2870322 D COG0807 GTP cyclohydrolase II; GTP cyclohydrolase II 2869732..2870322 Escherichia coli O104:H4 str. 2011C-3493 13702436 YP_006779478.1 CDS O3K_13960 NC_018658.1 2870386 2873061 R COG1048 Aconitase A; aconitate hydratase complement(2870386..2873061) Escherichia coli O104:H4 str. 2011C-3493 13702437 YP_006779479.1 CDS O3K_13965 NC_018658.1 2873235 2873360 D hypothetical protein 2873235..2873360 Escherichia coli O104:H4 str. 2011C-3493 13702438 YP_006779480.1 CDS O3K_13970 NC_018658.1 2873434 2873601 R hypothetical protein complement(2873434..2873601) Escherichia coli O104:H4 str. 2011C-3493 13702439 YP_006779481.1 CDS O3K_13975 NC_018658.1 2873604 2873732 R hypothetical protein complement(2873604..2873732) Escherichia coli O104:H4 str. 2011C-3493 13702440 YP_006779482.1 CDS cysB NC_018658.1 2874062 2875036 R COG0583 Transcriptional regulator; transcriptional regulator CysB complement(2874062..2875036) Escherichia coli O104:H4 str. 2011C-3493 13702441 YP_006779483.1 CDS O3K_13985 NC_018658.1 2875246 2877843 R COG0550 Topoisomerase IA; DNA topoisomerase I subunit omega complement(2875246..2877843) Escherichia coli O104:H4 str. 2011C-3493 13702442 YP_006779484.1 CDS O3K_13990 NC_018658.1 2878223 2878474 D hypothetical protein 2878223..2878474 Escherichia coli O104:H4 str. 2011C-3493 13702443 YP_006779485.1 CDS O3K_13995 NC_018658.1 2878510 2879559 R COG0616 Periplasmic serine proteases (ClpP class); putative inner membrane peptidase complement(2878510..2879559) Escherichia coli O104:H4 str. 2011C-3493 13702515 YP_006779486.1 CDS O3K_14000 NC_018658.1 2879779 2880537 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative oxoacyl-(acyl carrier protein) reductase 2879779..2880537 Escherichia coli O104:H4 str. 2011C-3493 13702516 YP_006779487.1 CDS O3K_14005 NC_018658.1 2880534 2881124 D COG2109 ATP:corrinoid adenosyltransferase; cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase 2880534..2881124 Escherichia coli O104:H4 str. 2011C-3493 13702517 YP_006779488.1 CDS O3K_14010 NC_018658.1 2881164 2882036 R COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridylate synthase B complement(2881164..2882036) Escherichia coli O104:H4 str. 2011C-3493 13702518 YP_006779489.1 CDS O3K_14015 NC_018658.1 2882137 2882757 R COG0009 Putative translation factor (SUA5); hypothetical protein complement(2882137..2882757) Escherichia coli O104:H4 str. 2011C-3493 13702519 YP_006779490.1 CDS O3K_14020 NC_018658.1 2882754 2883635 R COG0613 Predicted metal-dependent phosphoesterases (PHP family); hypothetical protein complement(2882754..2883635) Escherichia coli O104:H4 str. 2011C-3493 13702520 YP_006779491.1 CDS O3K_14025 NC_018658.1 2883909 2885471 D COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate synthase component I 2883909..2885471 Escherichia coli O104:H4 str. 2011C-3493 13702521 YP_006779492.1 CDS O3K_14030 NC_018658.1 2885471 2887066 D COG0512 Anthranilate/para-aminobenzoate synthases component II; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 2885471..2887066 Escherichia coli O104:H4 str. 2011C-3493 13702522 YP_006779493.1 CDS O3K_14035 NC_018658.1 2887070 2888428 D COG0134 Indole-3-glycerol phosphate synthase; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 2887070..2888428 Escherichia coli O104:H4 str. 2011C-3493 13702523 YP_006779494.1 CDS O3K_14040 NC_018658.1 2888440 2889633 D COG0133 Tryptophan synthase beta chain; tryptophan synthase subunit beta 2888440..2889633 Escherichia coli O104:H4 str. 2011C-3493 13702524 YP_006779495.1 CDS trpA NC_018658.1 2889633 2890439 D COG0159 Tryptophan synthase alpha chain; tryptophan synthase subunit alpha 2889633..2890439 Escherichia coli O104:H4 str. 2011C-3493 13702525 YP_006779496.1 CDS O3K_14050 NC_018658.1 2891085 2891585 D COG3685 Uncharacterized protein conserved in bacteria; YciF protein 2891085..2891585 Escherichia coli O104:H4 str. 2011C-3493 13702526 YP_006779497.1 CDS O3K_14055 NC_018658.1 2891631 2892137 D COG3685 Uncharacterized protein conserved in bacteria; hypothetical protein 2891631..2892137 Escherichia coli O104:H4 str. 2011C-3493 13702527 YP_006779498.1 CDS O3K_14060 NC_018658.1 2892626 2892796 R tail component complement(2892626..2892796) Escherichia coli O104:H4 str. 2011C-3493 13702528 YP_006779499.1 CDS O3K_14065 NC_018658.1 2892911 2893180 R tail fiber assembly protein complement(2892911..2893180) Escherichia coli O104:H4 str. 2011C-3493 13702529 YP_006779500.1 CDS O3K_14070 NC_018658.1 2893249 2893905 D COG0500 SAM-dependent methyltransferases; hypothetical protein 2893249..2893905 Escherichia coli O104:H4 str. 2011C-3493 13702530 YP_006779501.1 CDS O3K_14075 NC_018658.1 2893960 2894544 R putative tail fiber chaperone, Qin prophage complement(2893960..2894544) Escherichia coli O104:H4 str. 2011C-3493 13702531 YP_006779502.1 CDS O3K_14080 NC_018658.1 2894544 2897378 R putative phage tail fiber protein complement(2894544..2897378) Escherichia coli O104:H4 str. 2011C-3493 13702532 YP_006779503.1 CDS O3K_14085 NC_018658.1 2897530 2898129 R putative outer membrane Lom complement(2897530..2898129) Escherichia coli O104:H4 str. 2011C-3493 13702533 YP_006779504.1 CDS O3K_14090 NC_018658.1 2898197 2901676 R COG4733 Phage-related protein, tail component; Host specificity protein J complement(2898197..2901676) Escherichia coli O104:H4 str. 2011C-3493 13702534 YP_006779505.1 CDS O3K_14095 NC_018658.1 2902155 2902796 R COG4723 Phage-related protein, tail component; Tail assembly protein I from prophage complement(2902155..2902796) Escherichia coli O104:H4 str. 2011C-3493 13702535 YP_006779506.1 CDS O3K_14100 NC_018658.1 2902694 2903437 R COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; tail fiber component K of prophage complement(2902694..2903437) Escherichia coli O104:H4 str. 2011C-3493 13702536 YP_006779507.1 CDS O3K_14105 NC_018658.1 2903442 2904140 R COG4672 Phage-related protein; Minor tail protein L complement(2903442..2904140) Escherichia coli O104:H4 str. 2011C-3493 13702537 YP_006779508.1 CDS O3K_14110 NC_018658.1 2904140 2904469 R COG4718 Phage-related protein; minor tail protein M complement(2904140..2904469) Escherichia coli O104:H4 str. 2011C-3493 13702538 YP_006779509.1 CDS O3K_14115 NC_018658.1 2904466 2907039 R COG5281 Phage-related minor tail protein; Minor tail protein precursor H complement(2904466..2907039) Escherichia coli O104:H4 str. 2011C-3493 13702539 YP_006779510.1 CDS O3K_14120 NC_018658.1 2907020 2907433 R tail protein complement(2907020..2907433) Escherichia coli O104:H4 str. 2011C-3493 13702540 YP_006779511.1 CDS O3K_14125 NC_018658.1 2907460 2907891 R Minor tail protein G complement(2907460..2907891) Escherichia coli O104:H4 str. 2011C-3493 13702541 YP_006779512.1 CDS O3K_14130 NC_018658.1 2907905 2908567 R COG5492 Bacterial surface proteins containing Ig-like domains; tail protein complement(2907905..2908567) Escherichia coli O104:H4 str. 2011C-3493 13702542 YP_006779513.1 CDS O3K_14135 NC_018658.1 2908663 2909058 R putative minor tail protein complement(2908663..2909058) Escherichia coli O104:H4 str. 2011C-3493 13702543 YP_006779514.1 CDS O3K_14140 NC_018658.1 2909055 2909630 R Minor tail protein Z (GpZ) complement(2909055..2909630) Escherichia coli O104:H4 str. 2011C-3493 13702544 YP_006779515.1 CDS O3K_14145 NC_018658.1 2909645 2909998 R Tail attachment protein (Minor capsid protein FII) complement(2909645..2909998) Escherichia coli O104:H4 str. 2011C-3493 13702545 YP_006779516.1 CDS O3K_14150 NC_018658.1 2909991 2910359 R putative DNA packaging protein from phage origin complement(2909991..2910359) Escherichia coli O104:H4 str. 2011C-3493 13702546 YP_006779517.1 CDS O3K_14155 NC_018658.1 2910411 2911439 R major head protein complement(2910411..2911439) Escherichia coli O104:H4 str. 2011C-3493 13702547 YP_006779518.1 CDS O3K_14160 NC_018658.1 2911497 2911844 R putative head-DNA stabilization protein complement(2911497..2911844) Escherichia coli O104:H4 str. 2011C-3493 13702548 YP_006779519.1 CDS O3K_14165 NC_018658.1 2911881 2913386 R COG0616 Periplasmic serine proteases (ClpP class); head-tail preconnector protein GP5 complement(2911881..2913386) Escherichia coli O104:H4 str. 2011C-3493 13702549 YP_006779520.1 CDS O3K_14170 NC_018658.1 2913376 2914968 R COG5511 Bacteriophage capsid protein; head protein Gp4 complement(2913376..2914968) Escherichia coli O104:H4 str. 2011C-3493 13702550 YP_006779521.1 CDS O3K_14175 NC_018658.1 2914965 2915171 R head completion protein complement(2914965..2915171) Escherichia coli O104:H4 str. 2011C-3493 13702551 YP_006779522.1 CDS O3K_14180 NC_018658.1 2915155 2917083 R COG5525 Bacteriophage tail assembly protein; Terminase large subunit (Gp2) complement(2915155..2917083) Escherichia coli O104:H4 str. 2011C-3493 13702552 YP_006779523.1 CDS O3K_14185 NC_018658.1 2917055 2917603 R COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; prophage Qin DNA packaging protein NU1-like protein complement(2917055..2917603) Escherichia coli O104:H4 str. 2011C-3493 13702553 YP_006779524.1 CDS O3K_14190 NC_018658.1 2917685 2917957 R hypothetical protein complement(2917685..2917957) Escherichia coli O104:H4 str. 2011C-3493 13702554 YP_006779525.1 CDS O3K_14195 NC_018658.1 2918004 2918408 R hypothetical protein complement(2918004..2918408) Escherichia coli O104:H4 str. 2011C-3493 13702555 YP_006779526.1 CDS O3K_14200 NC_018658.1 2918544 2918768 R hypothetical protein complement(2918544..2918768) Escherichia coli O104:H4 str. 2011C-3493 13702556 YP_006779527.1 CDS O3K_14205 NC_018658.1 2918862 2919149 R hypothetical protein complement(2918862..2919149) Escherichia coli O104:H4 str. 2011C-3493 13702557 YP_006779528.1 CDS O3K_14210 NC_018658.1 2919228 2919371 R hypothetical protein complement(2919228..2919371) Escherichia coli O104:H4 str. 2011C-3493 13702558 YP_006779529.1 CDS O3K_14215 NC_018658.1 2919368 2919835 R endopeptidase complement(2919368..2919835) Escherichia coli O104:H4 str. 2011C-3493 13702559 YP_006779530.1 CDS O3K_14220 NC_018658.1 2919935 2920150 R hypothetical protein complement(2919935..2920150) Escherichia coli O104:H4 str. 2011C-3493 13702560 YP_006779531.1 CDS O3K_14225 NC_018658.1 2920188 2920400 R COG5178 U5 snRNP spliceosome subunit; hypothetical protein complement(2920188..2920400) Escherichia coli O104:H4 str. 2011C-3493 13702561 YP_006779532.1 CDS O3K_14230 NC_018658.1 2920478 2921011 R COG3772 Phage-related lysozyme (muraminidase); phage-related lysozyme (muraminidase) complement(2920478..2921011) Escherichia coli O104:H4 str. 2011C-3493 13702562 YP_006779533.1 CDS O3K_14235 NC_018658.1 2921054 2921860 R phage protein complement(2921054..2921860) Escherichia coli O104:H4 str. 2011C-3493 13702563 YP_006779534.1 CDS O3K_14240 NC_018658.1 2921865 2922080 R lysis protein S of prophage CP-933V complement(2921865..2922080) Escherichia coli O104:H4 str. 2011C-3493 13702564 YP_006779535.1 CDS O3K_14245 NC_018658.1 2922231 2924084 R prophage protein complement(2922231..2924084) Escherichia coli O104:H4 str. 2011C-3493 13702565 YP_006779536.1 CDS O3K_14250 NC_018658.1 2924345 2924680 D anti-adapter protein IraM 2924345..2924680 Escherichia coli O104:H4 str. 2011C-3493 13702566 YP_006779537.1 CDS O3K_14255 NC_018658.1 2925128 2925406 R hypothetical protein complement(2925128..2925406) Escherichia coli O104:H4 str. 2011C-3493 13702567 YP_006779538.1 CDS O3K_14260 NC_018658.1 2925891 2926940 R COG0863 DNA modification methylase; DNA adenine methyltransferase ( DNA methylase) from phage origin complement(2925891..2926940) Escherichia coli O104:H4 str. 2011C-3493 13702571 YP_006779539.1 CDS O3K_14265 NC_018658.1 2927091 2927288 R hypothetical protein complement(2927091..2927288) Escherichia coli O104:H4 str. 2011C-3493 13702572 YP_006779540.1 CDS O3K_14270 NC_018658.1 2927515 2928336 R COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; antitermination protein Q of prophage complement(2927515..2928336) Escherichia coli O104:H4 str. 2011C-3493 13702573 YP_006779541.1 CDS O3K_14275 NC_018658.1 2928333 2928707 R COG4570 Holliday junction resolvase; holliday junction resolvase complement(2928333..2928707) Escherichia coli O104:H4 str. 2011C-3493 13702574 YP_006779542.1 CDS O3K_14280 NC_018658.1 2928720 2929766 R hypothetical protein complement(2928720..2929766) Escherichia coli O104:H4 str. 2011C-3493 13702575 YP_006779543.1 CDS O3K_14285 NC_018658.1 2929987 2930166 D hypothetical protein 2929987..2930166 Escherichia coli O104:H4 str. 2011C-3493 13702576 YP_006779544.1 CDS O3K_14290 NC_018658.1 2930208 2930420 R cell killing protein encoded within cryptic prophage CP-933M complement(2930208..2930420) Escherichia coli O104:H4 str. 2011C-3493 13702577 YP_006779545.1 CDS O3K_14295 NC_018658.1 2930601 2931287 R COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2930601..2931287) Escherichia coli O104:H4 str. 2011C-3493 13702578 YP_006779546.1 CDS O3K_14300 NC_018658.1 2931441 2931866 R phage protein complement(2931441..2931866) Escherichia coli O104:H4 str. 2011C-3493 13702579 YP_006779547.1 CDS O3K_14305 NC_018658.1 2931907 2932869 R putative replication protein complement(2931907..2932869) Escherichia coli O104:H4 str. 2011C-3493 13702580 YP_006779548.1 CDS O3K_14310 NC_018658.1 2932892 2933317 R putative phage regulatory protein CII complement(2932892..2933317) Escherichia coli O104:H4 str. 2011C-3493 13702581 YP_006779549.1 CDS O3K_14315 NC_018658.1 2933314 2933568 R regulatory protein complement(2933314..2933568) Escherichia coli O104:H4 str. 2011C-3493 13702582 YP_006779550.1 CDS O3K_14320 NC_018658.1 2933648 2934067 D COG1396 Predicted transcriptional regulators; phage repressor protein CI 2933648..2934067 Escherichia coli O104:H4 str. 2011C-3493 13702583 YP_006779551.1 CDS O3K_14325 NC_018658.1 2934364 2934516 D hypothetical protein 2934364..2934516 Escherichia coli O104:H4 str. 2011C-3493 13700923 YP_006779552.1 CDS O3K_14330 NC_018658.1 2934528 2934866 D hypothetical protein 2934528..2934866 Escherichia coli O104:H4 str. 2011C-3493 13700924 YP_006779553.1 CDS O3K_14335 NC_018658.1 2934855 2935049 R hypothetical protein complement(2934855..2935049) Escherichia coli O104:H4 str. 2011C-3493 13700925 YP_006779554.1 CDS O3K_14340 NC_018658.1 2935616 2935804 D regulator of cell division encoded by prophage 2935616..2935804 Escherichia coli O104:H4 str. 2011C-3493 13700926 YP_006779555.1 CDS O3K_14345 NC_018658.1 2935801 2935992 D hypothetical protein 2935801..2935992 Escherichia coli O104:H4 str. 2011C-3493 13700927 YP_006779556.1 CDS O3K_14350 NC_018658.1 2936085 2938556 D putative exonuclease from phage origin 2936085..2938556 Escherichia coli O104:H4 str. 2011C-3493 13700928 YP_006779557.1 CDS O3K_14355 NC_018658.1 2938621 2938869 D Excisionase 2938621..2938869 Escherichia coli O104:H4 str. 2011C-3493 13700929 YP_006779558.1 CDS O3K_14360 NC_018658.1 2938847 2939977 D COG0582 Integrase; putative integrase 2938847..2939977 Escherichia coli O104:H4 str. 2011C-3493 13700930 YP_006779559.1 CDS O3K_14365 NC_018658.1 2940023 2940661 R COG3047 Outer membrane protein W; outer membrane protein W complement(2940023..2940661) Escherichia coli O104:H4 str. 2011C-3493 13700931 YP_006779560.1 CDS O3K_14370 NC_018658.1 2941018 2941761 D hypothetical protein 2941018..2941761 Escherichia coli O104:H4 str. 2011C-3493 13700932 YP_006779561.1 CDS O3K_14375 NC_018658.1 2941791 2942330 D COG2917 Intracellular septation protein A; intracellular septation protein A 2941791..2942330 Escherichia coli O104:H4 str. 2011C-3493 13700933 YP_006779562.1 CDS O3K_14380 NC_018658.1 2942435 2942833 D COG1607 Acyl-CoA hydrolase; acyl-CoA esterase 2942435..2942833 Escherichia coli O104:H4 str. 2011C-3493 13700934 YP_006779563.1 CDS O3K_14385 NC_018658.1 2942873 2943592 R COG0810 Periplasmic protein TonB, links inner and outer membranes; transporter complement(2942873..2943592) Escherichia coli O104:H4 str. 2011C-3493 13700935 YP_006779564.1 CDS O3K_14390 NC_018658.1 2943816 2944112 D COG2350 Uncharacterized protein conserved in bacteria; YciI-like protein 2943816..2944112 Escherichia coli O104:H4 str. 2011C-3493 13700936 YP_006779565.1 CDS O3K_14395 NC_018658.1 2944412 2945665 D COG1226 Kef-type K+ transport systems, predicted NAD-binding component; voltage-gated potassium channel 2944412..2945665 Escherichia coli O104:H4 str. 2011C-3493 13700937 YP_006779566.1 CDS cls NC_018658.1 2946036 2947496 D COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; cardiolipin synthetase 2946036..2947496 Escherichia coli O104:H4 str. 2011C-3493 13700938 YP_006779567.1 CDS O3K_14405 NC_018658.1 2947531 2947860 D COG3099 Uncharacterized protein conserved in bacteria; dsDNA-mimic protein 2947531..2947860 Escherichia coli O104:H4 str. 2011C-3493 13700939 YP_006779568.1 CDS O3K_14410 NC_018658.1 2947913 2948917 R COG4608 ABC-type oligopeptide transport system, ATPase component; oligopeptide ABC transporter ATP-binding protein OppF complement(2947913..2948917) Escherichia coli O104:H4 str. 2011C-3493 13700940 YP_006779569.1 CDS oppD NC_018658.1 2948914 2949927 R COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; oligopeptide ABC transporter ATP-binding protein complement(2948914..2949927) Escherichia coli O104:H4 str. 2011C-3493 13700941 YP_006779570.1 CDS O3K_14420 NC_018658.1 2949939 2950847 R COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; oligopeptide ABC transporter permease OppC complement(2949939..2950847) Escherichia coli O104:H4 str. 2011C-3493 13700942 YP_006779571.1 CDS oppB NC_018658.1 2950862 2951782 R COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; oligopeptide transporter permease complement(2950862..2951782) Escherichia coli O104:H4 str. 2011C-3493 13700943 YP_006779572.1 CDS O3K_14430 NC_018658.1 2951868 2953499 R COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein OppA complement(2951868..2953499) Escherichia coli O104:H4 str. 2011C-3493 13700944 YP_006779573.1 CDS O3K_14435 NC_018658.1 2954237 2954884 R COG2095 Multiple antibiotic transporter; hypothetical protein complement(2954237..2954884) Escherichia coli O104:H4 str. 2011C-3493 13700945 YP_006779574.1 CDS O3K_14440 NC_018658.1 2955361 2958036 D COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2955361..2958036 Escherichia coli O104:H4 str. 2011C-3493 13700946 YP_006779575.1 CDS O3K_14460 NC_018658.1 2959342 2959959 R COG1435 Thymidine kinase; thymidine kinase complement(2959342..2959959) Escherichia coli O104:H4 str. 2011C-3493 13700947 YP_006779576.1 CDS O3K_14465 NC_018658.1 2960565 2960978 D COG2916 DNA-binding protein H-NS; global DNA-binding transcriptional dual regulator H-NS 2960565..2960978 Escherichia coli O104:H4 str. 2011C-3493 13700948 YP_006779577.1 CDS O3K_14470 NC_018658.1 2961122 2962030 R COG1210 UDP-glucose pyrophosphorylase; UTP--glucose-1-phosphate uridylyltransferase subunit GalU complement(2961122..2962030) Escherichia coli O104:H4 str. 2011C-3493 13700949 YP_006779578.1 CDS O3K_14475 NC_018658.1 2962232 2963245 R COG0784 FOG: CheY-like receiver; response regulator of RpoS complement(2962232..2963245) Escherichia coli O104:H4 str. 2011C-3493 13700950 YP_006779579.1 CDS O3K_14480 NC_018658.1 2963337 2964242 R COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein complement(2963337..2964242) Escherichia coli O104:H4 str. 2011C-3493 13700951 YP_006779580.1 CDS O3K_14485 NC_018658.1 2964355 2964813 D COG3012 Uncharacterized protein conserved in bacteria; hypothetical protein 2964355..2964813 Escherichia coli O104:H4 str. 2011C-3493 13700952 YP_006779581.1 CDS purU NC_018658.1 2964863 2965705 D COG0788 Formyltetrahydrofolate hydrolase; formyltetrahydrofolate deformylase 2964863..2965705 Escherichia coli O104:H4 str. 2011C-3493 13700953 YP_006779582.1 CDS O3K_14505 NC_018658.1 2966430 2967107 R COG2181 Nitrate reductase gamma subunit; Respiratory nitrate reductase subunit gamma complement(2966430..2967107) Escherichia coli O104:H4 str. 2011C-3493 13700957 YP_006779583.1 CDS O3K_14510 NC_018658.1 2967107 2967817 R COG2180 Nitrate reductase delta subunit; molybdenum-cofactor-assembly chaperone subunit delta complement(2967107..2967817) Escherichia coli O104:H4 str. 2011C-3493 13700958 YP_006779584.1 CDS O3K_14515 NC_018658.1 2967814 2969352 R COG1140 Nitrate reductase beta subunit; nitrate reductase subunit beta complement(2967814..2969352) Escherichia coli O104:H4 str. 2011C-3493 13700959 YP_006779585.1 CDS O3K_14520 NC_018658.1 2969349 2973092 R COG5013 Nitrate reductase alpha subunit; nitrate reductase subunit alpha complement(2969349..2973092) Escherichia coli O104:H4 str. 2011C-3493 13700960 YP_006779586.1 CDS O3K_14525 NC_018658.1 2973608 2974999 R COG2223 Nitrate/nitrite transporter; nitrite extrusion protein complement(2973608..2974999) Escherichia coli O104:H4 str. 2011C-3493 13700961 YP_006779587.1 CDS O3K_14530 NC_018658.1 2975338 2977134 D COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific; nitrate/nitrite sensor protein NarX 2975338..2977134 Escherichia coli O104:H4 str. 2011C-3493 13700962 YP_006779588.1 CDS O3K_14535 NC_018658.1 2977127 2977777 D DNA-binding transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; nitrate/nitrite response regulator protein NarL 2977127..2977777 Escherichia coli O104:H4 str. 2011C-3493 13700963 YP_006779589.1 CDS O3K_14540 NC_018658.1 2977778 2979031 R putative invasin complement(2977778..2979031) Escherichia coli O104:H4 str. 2011C-3493 13700964 YP_006779590.1 CDS O3K_14545 NC_018658.1 2979357 2979710 D COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction; hypothetical protein 2979357..2979710 Escherichia coli O104:H4 str. 2011C-3493 13700965 YP_006779591.1 CDS O3K_14550 NC_018658.1 2979754 2980470 R COG3703 Uncharacterized protein involved in cation transport; regulatory protein for cation transport complement(2979754..2980470) Escherichia coli O104:H4 str. 2011C-3493 13700966 YP_006779592.1 CDS chaB NC_018658.1 2980607 2980837 R COG4572 Putative cation transport regulator; cation transport regulator complement(2980607..2980837) Escherichia coli O104:H4 str. 2011C-3493 13700967 YP_006779593.1 CDS O3K_14560 NC_018658.1 2981107 2982207 D COG0387 Ca2+/H+ antiporter; calcium/sodium:proton antiporter 2981107..2982207 Escherichia coli O104:H4 str. 2011C-3493 13700968 YP_006779594.1 CDS O3K_14565 NC_018658.1 2982612 2982719 D hypothetical protein 2982612..2982719 Escherichia coli O104:H4 str. 2011C-3493 13700969 YP_006779595.1 CDS O3K_14570 NC_018658.1 2983148 2983255 D small toxic polypeptide 2983148..2983255 Escherichia coli O104:H4 str. 2011C-3493 13700970 YP_006779596.1 CDS O3K_14575 NC_018658.1 2983683 2983790 D hypothetical protein 2983683..2983790 Escherichia coli O104:H4 str. 2011C-3493 13700971 YP_006779597.1 CDS O3K_14580 NC_018658.1 2983939 2984793 R COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; 2-dehydro-3-deoxyphosphooctonate aldolase complement(2983939..2984793) Escherichia coli O104:H4 str. 2011C-3493 13700972 YP_006779598.1 CDS O3K_14585 NC_018658.1 2984829 2985638 R COG2912 Uncharacterized conserved protein; hypothetical protein complement(2984829..2985638) Escherichia coli O104:H4 str. 2011C-3493 13700973 YP_006779599.1 CDS O3K_14590 NC_018658.1 2985642 2986034 R COG3094 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2985642..2986034) Escherichia coli O104:H4 str. 2011C-3493 13700974 YP_006779600.1 CDS O3K_14595 NC_018658.1 2986031 2986864 R COG2890 Methylase of polypeptide chain release factors; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2986031..2986864) Escherichia coli O104:H4 str. 2011C-3493 13700975 YP_006779601.1 CDS prfA NC_018658.1 2986864 2987946 R COG0216 Protein chain release factor A; peptide chain release factor 1 complement(2986864..2987946) Escherichia coli O104:H4 str. 2011C-3493 13700976 YP_006779602.1 CDS hemA NC_018658.1 2987988 2989244 R COG0373 Glutamyl-tRNA reductase; glutamyl-tRNA reductase complement(2987988..2989244) Escherichia coli O104:H4 str. 2011C-3493 13700977 YP_006779603.1 CDS lolB NC_018658.1 2989458 2990081 D COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis; outer membrane lipoprotein LolB 2989458..2990081 Escherichia coli O104:H4 str. 2011C-3493 13700978 YP_006779604.1 CDS ipk NC_018658.1 2990081 2990932 D COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2990081..2990932 Escherichia coli O104:H4 str. 2011C-3493 13700979 YP_006779605.1 CDS O3K_14620 NC_018658.1 2991083 2992030 D COG0462 Phosphoribosylpyrophosphate synthetase; ribose-phosphate pyrophosphokinase 2991083..2992030 Escherichia coli O104:H4 str. 2011C-3493 13700980 YP_006779606.1 CDS O3K_14625 NC_018658.1 2992155 2993834 D COG0659 Sulfate permease and related transporters (MFS superfamily); transporter 2992155..2993834 Escherichia coli O104:H4 str. 2011C-3493 13700981 YP_006779607.1 CDS O3K_14630 NC_018658.1 2993889 2994167 R hypothetical protein complement(2993889..2994167) Escherichia coli O104:H4 str. 2011C-3493 13700982 YP_006779608.1 CDS O3K_14635 NC_018658.1 2994445 2995029 D COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 2994445..2995029 Escherichia coli O104:H4 str. 2011C-3493 13700983 YP_006779609.1 CDS O3K_14640 NC_018658.1 2995146 2996237 D COG0012 Predicted GTPase, probable translation factor; GTP-binding protein YchF 2995146..2996237 Escherichia coli O104:H4 str. 2011C-3493 13700984 YP_006779610.1 CDS O3K_14645 NC_018658.1 2996482 2996661 R hypothetical protein complement(2996482..2996661) Escherichia coli O104:H4 str. 2011C-3493 13700985 YP_006779611.1 CDS O3K_14650 NC_018658.1 2997006 2999873 D COG3468 Type V secretory pathway, adhesin AidA; adhesin, autotransporter 2997006..2999873 Escherichia coli O104:H4 str. 2011C-3493 13700986 YP_006779612.1 CDS O3K_14655 NC_018658.1 2999973 3001892 R COG3284 Transcriptional activator of acetoin/glycerol metabolism; DNA-binding transcriptional regulator DhaR complement(2999973..3001892) Escherichia coli O104:H4 str. 2011C-3493 13700987 YP_006779613.1 CDS O3K_14660 NC_018658.1 3002120 3003190 D COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 3002120..3003190 Escherichia coli O104:H4 str. 2011C-3493 13700988 YP_006779614.1 CDS O3K_14665 NC_018658.1 3003201 3003833 D COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaL 3003201..3003833 Escherichia coli O104:H4 str. 2011C-3493 13700989 YP_006779615.1 CDS O3K_14670 NC_018658.1 3003844 3005262 D COG3412 Uncharacterized protein conserved in bacteria; dihydroxyacetone kinase subunit DhaM 3003844..3005262 Escherichia coli O104:H4 str. 2011C-3493 13700990 YP_006779616.1 CDS treA NC_018658.1 3005582 3007279 D COG1626 Neutral trehalase; trehalase 3005582..3007279 Escherichia coli O104:H4 str. 2011C-3493 13700991 YP_006779617.1 CDS O3K_14680 NC_018658.1 3007358 3007798 R hypothetical protein complement(3007358..3007798) Escherichia coli O104:H4 str. 2011C-3493 13700992 YP_006779618.1 CDS O3K_14685 NC_018658.1 3007976 3008230 R COG2261 Predicted membrane protein; transglycosylase-associated protein complement(3007976..3008230) Escherichia coli O104:H4 str. 2011C-3493 13700993 YP_006779619.1 CDS O3K_14690 NC_018658.1 3008431 3009165 D COG5581 Predicted glycosyltransferase; flagellar function protein 3008431..3009165 Escherichia coli O104:H4 str. 2011C-3493 13700994 YP_006779620.1 CDS emtA NC_018658.1 3009167 3009778 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic murein endotransglycosylase E complement(3009167..3009778) Escherichia coli O104:H4 str. 2011C-3493 13700995 YP_006779621.1 CDS ldcA NC_018658.1 3009878 3010792 D COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; L,D-carboxypeptidase A 3009878..3010792 Escherichia coli O104:H4 str. 2011C-3493 13700996 YP_006779622.1 CDS O3K_14705 NC_018658.1 3010887 3012623 D COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain; potassium/proton antiporter 3010887..3012623 Escherichia coli O104:H4 str. 2011C-3493 13700997 YP_006779623.1 CDS dadX NC_018658.1 3013009 3014079 R COG0787 Alanine racemase; alanine racemase complement(3013009..3014079) Escherichia coli O104:H4 str. 2011C-3493 13700998 YP_006779624.1 CDS O3K_14715 NC_018658.1 3014089 3015387 R COG0665 Glycine/D-amino acid oxidases (deaminating); D-amino acid dehydrogenase small subunit complement(3014089..3015387) Escherichia coli O104:H4 str. 2011C-3493 13700999 YP_006779625.1 CDS O3K_14720 NC_018658.1 3015717 3017249 D COG2719 Uncharacterized conserved protein; SpoVR family protein 3015717..3017249 Escherichia coli O104:H4 str. 2011C-3493 13701000 YP_006779626.1 CDS O3K_14725 NC_018658.1 3017301 3018020 R COG2186 Transcriptional regulators; fatty acid metabolism regulator complement(3017301..3018020) Escherichia coli O104:H4 str. 2011C-3493 13701001 YP_006779627.1 CDS nhaB NC_018658.1 3018242 3019783 D COG3067 Na+/H+ antiporter; sodium/proton antiporter 3018242..3019783 Escherichia coli O104:H4 str. 2011C-3493 13701002 YP_006779628.1 CDS O3K_14735 NC_018658.1 3019929 3020459 D COG1495 Disulfide bond formation protein DsbB; disulfide bond formation protein B 3019929..3020459 Escherichia coli O104:H4 str. 2011C-3493 13701003 YP_006779629.1 CDS umuC NC_018658.1 3020505 3021773 R COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC complement(3020505..3021773) Escherichia coli O104:H4 str. 2011C-3493 13701004 YP_006779630.1 CDS O3K_14745 NC_018658.1 3021773 3022192 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); DNA polymerase V subunit UmuD complement(3021773..3022192) Escherichia coli O104:H4 str. 2011C-3493 13701005 YP_006779631.1 CDS hlyE NC_018658.1 3023194 3023475 D hemolysin E 3023194..3023475 Escherichia coli O104:H4 str. 2011C-3493 13701006 YP_006779632.1 CDS O3K_14765 NC_018658.1 3023682 3024128 R COG2983 Uncharacterized conserved protein; hypothetical protein complement(3023682..3024128) Escherichia coli O104:H4 str. 2011C-3493 13701007 YP_006779633.1 CDS O3K_14770 NC_018658.1 3024220 3024879 R COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); hypothetical protein complement(3024220..3024879) Escherichia coli O104:H4 str. 2011C-3493 13701008 YP_006779634.1 CDS O3K_14775 NC_018658.1 3024951 3025277 R COG3100 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3024951..3025277) Escherichia coli O104:H4 str. 2011C-3493 13701009 YP_006779635.1 CDS O3K_14780 NC_018658.1 3025486 3025887 D hypothetical protein 3025486..3025887 Escherichia coli O104:H4 str. 2011C-3493 13701010 YP_006779636.1 CDS O3K_14785 NC_018658.1 3026007 3026375 R hypothetical protein complement(3026007..3026375) Escherichia coli O104:H4 str. 2011C-3493 13701011 YP_006779637.1 CDS minC NC_018658.1 3026895 3027590 D COG0850 Septum formation inhibitor; septum formation inhibitor 3026895..3027590 Escherichia coli O104:H4 str. 2011C-3493 13701012 YP_006779638.1 CDS O3K_14795 NC_018658.1 3027614 3028426 D COG2894 Septum formation inhibitor-activating ATPase; cell division inhibitor MinD 3027614..3028426 Escherichia coli O104:H4 str. 2011C-3493 13701013 YP_006779639.1 CDS minE NC_018658.1 3028430 3028696 D COG0851 Septum formation topological specificity factor; cell division topological specificity factor MinE 3028430..3028696 Escherichia coli O104:H4 str. 2011C-3493 13701014 YP_006779640.1 CDS O3K_14805 NC_018658.1 3029068 3029280 R adhesin complement(3029068..3029280) Escherichia coli O104:H4 str. 2011C-3493 13701015 YP_006779641.1 CDS O3K_14810 NC_018658.1 3030048 3030332 D hypothetical protein 3030048..3030332 Escherichia coli O104:H4 str. 2011C-3493 13701016 YP_006779642.1 CDS O3K_14815 NC_018658.1 3030342 3030671 D hypothetical protein 3030342..3030671 Escherichia coli O104:H4 str. 2011C-3493 13701017 YP_006779643.1 CDS O3K_14820 NC_018658.1 3030728 3033049 R COG3468 Type V secretory pathway, adhesin AidA; putative autotransporter complement(3030728..3033049) Escherichia coli O104:H4 str. 2011C-3493 13701018 YP_006779644.1 CDS O3K_14825 NC_018658.1 3033166 3033375 R hypothetical protein complement(3033166..3033375) Escherichia coli O104:H4 str. 2011C-3493 13701019 YP_006779645.1 CDS O3K_14830 NC_018658.1 3033775 3033993 R hypothetical protein complement(3033775..3033993) Escherichia coli O104:H4 str. 2011C-3493 13701020 YP_006779646.1 CDS O3K_14835 NC_018658.1 3034125 3035648 R COG2200 FOG: EAL domain; hypothetical protein complement(3034125..3035648) Escherichia coli O104:H4 str. 2011C-3493 13701021 YP_006779647.1 CDS O3K_14840 NC_018658.1 3035980 3036228 R hypothetical protein complement(3035980..3036228) Escherichia coli O104:H4 str. 2011C-3493 13701022 YP_006779648.1 CDS O3K_14845 NC_018658.1 3036341 3036607 R hypothetical protein complement(3036341..3036607) Escherichia coli O104:H4 str. 2011C-3493 13701023 YP_006779649.1 CDS O3K_14850 NC_018658.1 3036636 3036908 R hypothetical protein complement(3036636..3036908) Escherichia coli O104:H4 str. 2011C-3493 13701024 YP_006779650.1 CDS O3K_14855 NC_018658.1 3036951 3037187 R hypothetical protein complement(3036951..3037187) Escherichia coli O104:H4 str. 2011C-3493 13701025 YP_006779651.1 CDS O3K_14860 NC_018658.1 3037501 3038712 D COG2200 FOG: EAL domain; cyclic-di-GMP phosphodiesterase, blue-light sensing protein using FAD (BLUF) 3037501..3038712 Escherichia coli O104:H4 str. 2011C-3493 13701026 YP_006779652.1 CDS O3K_14865 NC_018658.1 3038917 3039648 D COG0789 Predicted transcriptional regulators; putative DNA-binding transcriptional regulator 3038917..3039648 Escherichia coli O104:H4 str. 2011C-3493 13701027 YP_006779653.1 CDS O3K_14870 NC_018658.1 3039869 3040273 D COG5562 Phage envelope protein; hypothetical protein 3039869..3040273 Escherichia coli O104:H4 str. 2011C-3493 13701028 YP_006779654.1 CDS O3K_14875 NC_018658.1 3040969 3041292 D anti-adapter protein IraM 3040969..3041292 Escherichia coli O104:H4 str. 2011C-3493 13701029 YP_006779655.1 CDS O3K_14880 NC_018658.1 3041395 3042645 R COG0538 Isocitrate dehydrogenases; isocitrate dehydrogenase complement(3041395..3042645) Escherichia coli O104:H4 str. 2011C-3493 13701030 YP_006779656.1 CDS O3K_14885 NC_018658.1 3042817 3043470 D COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridine synthase E 3042817..3043470 Escherichia coli O104:H4 str. 2011C-3493 13701031 YP_006779657.1 CDS O3K_14890 NC_018658.1 3043480 3043941 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase 3043480..3043941 Escherichia coli O104:H4 str. 2011C-3493 13701032 YP_006779658.1 CDS mnmA NC_018658.1 3043995 3045101 D COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; tRNA-specific 2-thiouridylase MnmA 3043995..3045101 Escherichia coli O104:H4 str. 2011C-3493 13701033 YP_006779659.1 CDS O3K_14900 NC_018658.1 3045137 3045778 D COG2915 Uncharacterized protein involved in purine metabolism; putative lysogenization regulator 3045137..3045778 Escherichia coli O104:H4 str. 2011C-3493 13701034 YP_006779660.1 CDS O3K_14905 NC_018658.1 3045782 3047152 D COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 3045782..3047152 Escherichia coli O104:H4 str. 2011C-3493 13701035 YP_006779661.1 CDS O3K_14910 NC_018658.1 3047320 3047991 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator PhoP 3047320..3047991 Escherichia coli O104:H4 str. 2011C-3493 13701036 YP_006779662.1 CDS O3K_14915 NC_018658.1 3047991 3049451 D COG0642 Signal transduction histidine kinase; sensor protein PhoQ 3047991..3049451 Escherichia coli O104:H4 str. 2011C-3493 13701037 YP_006779663.1 CDS O3K_14920 NC_018658.1 3049527 3050648 D COG2850 Uncharacterized conserved protein; hypothetical protein 3049527..3050648 Escherichia coli O104:H4 str. 2011C-3493 13701038 YP_006779664.1 CDS O3K_14925 NC_018658.1 3050794 3052023 R COG2195 Di- and tripeptidases; peptidase T complement(3050794..3052023) Escherichia coli O104:H4 str. 2011C-3493 13701039 YP_006779665.1 CDS potA NC_018658.1 3052273 3053409 D COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; putrescine/spermidine ABC transporter ATPase 3052273..3053409 Escherichia coli O104:H4 str. 2011C-3493 13701040 YP_006779666.1 CDS potB NC_018658.1 3053393 3054250 D COG1176 ABC-type spermidine/putrescine transport system, permease component I; spermidine/putrescine ABC transporter permease 3053393..3054250 Escherichia coli O104:H4 str. 2011C-3493 13701041 YP_006779667.1 CDS potC NC_018658.1 3054247 3055041 D COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease 3054247..3055041 Escherichia coli O104:H4 str. 2011C-3493 13701042 YP_006779668.1 CDS potD NC_018658.1 3055038 3056084 D COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine ABC transporter substrate-binding protein 3055038..3056084 Escherichia coli O104:H4 str. 2011C-3493 13701043 YP_006779669.1 CDS O3K_14950 NC_018658.1 3056142 3056603 D inner membrane protein 3056142..3056603 Escherichia coli O104:H4 str. 2011C-3493 13701044 YP_006779670.1 CDS O3K_14955 NC_018658.1 3056678 3057388 D inner membrane protein 3056678..3057388 Escherichia coli O104:H4 str. 2011C-3493 13701045 YP_006779671.1 CDS O3K_14960 NC_018658.1 3057527 3058348 R COG0846 NAD-dependent protein deacetylases, SIR2 family; NAD-dependent deacetylase complement(3057527..3058348) Escherichia coli O104:H4 str. 2011C-3493 13701046 YP_006779672.1 CDS O3K_14965 NC_018658.1 3058364 3059275 R COG1940 Transcriptional regulator/sugar kinase; N-acetyl-D-glucosamine kinase complement(3058364..3059275) Escherichia coli O104:H4 str. 2011C-3493 13701047 YP_006779673.1 CDS O3K_14970 NC_018658.1 3059304 3060548 R COG4591 ABC-type transport system, involved in lipoprotein release, permease component; outer membrane-specific lipoprotein transporter subunit LolE complement(3059304..3060548) Escherichia coli O104:H4 str. 2011C-3493 13701048 YP_006779674.1 CDS lolD NC_018658.1 3060548 3061249 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; lipoprotein transporter ATP-binding subunit complement(3060548..3061249) Escherichia coli O104:H4 str. 2011C-3493 13701049 YP_006779675.1 CDS O3K_14980 NC_018658.1 3061242 3062441 R COG4591 ABC-type transport system, involved in lipoprotein release, permease component; outer membrane-specific lipoprotein transporter subunit LolC complement(3061242..3062441) Escherichia coli O104:H4 str. 2011C-3493 13701050 YP_006779676.1 CDS O3K_14985 NC_018658.1 3062703 3063776 D COG4763 Predicted membrane protein; inner membrane protein 3062703..3063776 Escherichia coli O104:H4 str. 2011C-3493 13701051 YP_006779677.1 CDS O3K_14990 NC_018658.1 3063904 3067350 D COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 3063904..3067350 Escherichia coli O104:H4 str. 2011C-3493 13701052 YP_006779678.1 CDS O3K_14995 NC_018658.1 3067494 3068456 D COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 3067494..3068456 Escherichia coli O104:H4 str. 2011C-3493 13701053 YP_006779679.1 CDS O3K_15000 NC_018658.1 3068539 3068796 R hypothetical protein complement(3068539..3068796) Escherichia coli O104:H4 str. 2011C-3493 13701054 YP_006779680.1 CDS O3K_15005 NC_018658.1 3069037 3069669 D COG1309 Transcriptional regulator; hypothetical protein 3069037..3069669 Escherichia coli O104:H4 str. 2011C-3493 13701055 YP_006779681.1 CDS O3K_15010 NC_018658.1 3069731 3070270 R COG3134 Predicted outer membrane lipoprotein; hypothetical protein complement(3069731..3070270) Escherichia coli O104:H4 str. 2011C-3493 13701056 YP_006779682.1 CDS O3K_15015 NC_018658.1 3070480 3071784 R COG1252 NADH dehydrogenase, FAD-containing subunit; respiratory NADH dehydrogenase 2/cupric reductase complement(3070480..3071784) Escherichia coli O104:H4 str. 2011C-3493 13701057 YP_006779683.1 CDS O3K_15020 NC_018658.1 3072192 3072734 R COG3150 Predicted esterase; hypothetical protein complement(3072192..3072734) Escherichia coli O104:H4 str. 2011C-3493 13701058 YP_006779684.1 CDS O3K_15025 NC_018658.1 3072757 3073782 R COG1472 Beta-glucosidase-related glycosidases; beta-hexosaminidase complement(3072757..3073782) Escherichia coli O104:H4 str. 2011C-3493 13701059 YP_006779685.1 CDS thiK NC_018658.1 3073793 3074617 R COG0510 Predicted choline kinase involved in LPS biosynthesis; thiamine kinase complement(3073793..3074617) Escherichia coli O104:H4 str. 2011C-3493 13701060 YP_006779686.1 CDS O3K_15035 NC_018658.1 3074598 3075239 R COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family); hypothetical protein complement(3074598..3075239) Escherichia coli O104:H4 str. 2011C-3493 13701061 YP_006779687.1 CDS O3K_15040 NC_018658.1 3075253 3075630 R COG5633 Predicted periplasmic lipoprotein; lipoprotein complement(3075253..3075630) Escherichia coli O104:H4 str. 2011C-3493 13701062 YP_006779688.1 CDS O3K_15045 NC_018658.1 3075633 3075992 R COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; purine nucleoside phosphoramidase complement(3075633..3075992) Escherichia coli O104:H4 str. 2011C-3493 13701063 YP_006779689.1 CDS O3K_15050 NC_018658.1 3076326 3078515 D COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid; ferric-rhodotorulic acid outer membrane transporter 3076326..3078515 Escherichia coli O104:H4 str. 2011C-3493 13701064 YP_006779690.1 CDS O3K_15055 NC_018658.1 3078575 3080008 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose-specific transporter subunit IIBC complement(3078575..3080008) Escherichia coli O104:H4 str. 2011C-3493 13701065 YP_006779691.1 CDS O3K_15060 NC_018658.1 3080303 3081100 R COG0084 Mg-dependent DNase; putative DNAse complement(3080303..3081100) Escherichia coli O104:H4 str. 2011C-3493 13701066 YP_006779692.1 CDS O3K_15065 NC_018658.1 3081111 3082115 R COG0470 ATPase involved in DNA replication; DNA polymerase III subunit delta' complement(3081111..3082115) Escherichia coli O104:H4 str. 2011C-3493 13701067 YP_006779693.1 CDS tmk NC_018658.1 3082112 3082753 R COG0125 Thymidylate kinase; thymidylate kinase complement(3082112..3082753) Escherichia coli O104:H4 str. 2011C-3493 13701068 YP_006779694.1 CDS O3K_15075 NC_018658.1 3082743 3083765 R COG1559 Predicted periplasmic solute-binding protein; putative aminodeoxychorismate lyase complement(3082743..3083765) Escherichia coli O104:H4 str. 2011C-3493 13701069 YP_006779695.1 CDS O3K_15080 NC_018658.1 3083768 3084577 R COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; 4-amino-4-deoxychorismate lyase complement(3083768..3084577) Escherichia coli O104:H4 str. 2011C-3493 13701070 YP_006779696.1 CDS O3K_15085 NC_018658.1 3084697 3085938 R COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-(acyl carrier protein) synthase II complement(3084697..3085938) Escherichia coli O104:H4 str. 2011C-3493 13701071 YP_006779697.1 CDS O3K_15090 NC_018658.1 3086026 3086262 R COG0236 Acyl carrier protein; hypothetical protein complement(3086026..3086262) Escherichia coli O104:H4 str. 2011C-3493 13701072 YP_006779698.1 CDS fabG NC_018658.1 3086473 3087207 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-ACP reductase complement(3086473..3087207) Escherichia coli O104:H4 str. 2011C-3493 13701073 YP_006779699.1 CDS O3K_15100 NC_018658.1 3087220 3088149 R COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl-CoA-[acyl-carrier-protein] transacylase complement(3087220..3088149) Escherichia coli O104:H4 str. 2011C-3493 13701074 YP_006779700.1 CDS O3K_15105 NC_018658.1 3088165 3089118 R COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-ACP synthase complement(3088165..3089118) Escherichia coli O104:H4 str. 2011C-3493 13701075 YP_006779701.1 CDS O3K_15110 NC_018658.1 3089186 3090256 R COG0416 Fatty acid/phospholipid biosynthesis enzyme; putative phosphate acyltransferase complement(3089186..3090256) Escherichia coli O104:H4 str. 2011C-3493 13701076 YP_006779702.1 CDS rpmF NC_018658.1 3090337 3090510 R COG0333 Ribosomal protein L32; 50S ribosomal protein L32 complement(3090337..3090510) Escherichia coli O104:H4 str. 2011C-3493 13701077 YP_006779703.1 CDS O3K_15120 NC_018658.1 3090562 3091083 R COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; hypothetical protein complement(3090562..3091083) Escherichia coli O104:H4 str. 2011C-3493 13701078 YP_006779704.1 CDS O3K_15125 NC_018658.1 3091282 3091866 D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; Maf-like protein 3091282..3091866 Escherichia coli O104:H4 str. 2011C-3493 13701079 YP_006779705.1 CDS O3K_15130 NC_018658.1 3091978 3092937 R COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA pseudouridylate synthase C complement(3091978..3092937) Escherichia coli O104:H4 str. 2011C-3493 13701080 YP_006779706.1 CDS O3K_15135 NC_018658.1 3093055 3093375 R hypothetical protein complement(3093055..3093375) Escherichia coli O104:H4 str. 2011C-3493 13701081 YP_006779707.1 CDS rne NC_018658.1 3093510 3096695 D COG1530 Ribonucleases G and E; ribonuclease E 3093510..3096695 Escherichia coli O104:H4 str. 2011C-3493 13701082 YP_006779708.1 CDS flgL NC_018658.1 3096892 3097845 R COG1344 Flagellin and related hook-associated proteins; flagellar hook-associated protein FlgL complement(3096892..3097845) Escherichia coli O104:H4 str. 2011C-3493 13701083 YP_006779709.1 CDS flgK NC_018658.1 3097857 3099500 R COG1256 Flagellar hook-associated protein; flagellar hook-associated protein FlgK complement(3097857..3099500) Escherichia coli O104:H4 str. 2011C-3493 13701084 YP_006779710.1 CDS flgJ NC_018658.1 3099566 3100507 R COG3951 Rod binding protein; flagellar rod assembly protein/muramidase FlgJ complement(3099566..3100507) Escherichia coli O104:H4 str. 2011C-3493 13701085 YP_006779711.1 CDS flgI NC_018658.1 3100507 3101604 R COG1706 Flagellar basal-body P-ring protein; flagellar basal body P-ring protein complement(3100507..3101604) Escherichia coli O104:H4 str. 2011C-3493 13701086 YP_006779712.1 CDS flgH NC_018658.1 3101616 3102314 R COG2063 Flagellar basal body L-ring protein; flagellar basal body L-ring protein complement(3101616..3102314) Escherichia coli O104:H4 str. 2011C-3493 13701087 YP_006779713.1 CDS flgG NC_018658.1 3102367 3103149 R COG4786 Flagellar basal body rod protein; flagellar basal body rod protein FlgG complement(3102367..3103149) Escherichia coli O104:H4 str. 2011C-3493 13701088 YP_006779714.1 CDS flgF NC_018658.1 3103321 3104076 R COG4787 Flagellar basal body rod protein; flagellar basal body rod protein FlgF complement(3103321..3104076) Escherichia coli O104:H4 str. 2011C-3493 13701089 YP_006779715.1 CDS flgE NC_018658.1 3104096 3105301 R COG1749 Flagellar hook protein FlgE; flagellar hook protein FlgE complement(3104096..3105301) Escherichia coli O104:H4 str. 2011C-3493 13701090 YP_006779716.1 CDS flgD NC_018658.1 3105326 3106021 R COG1843 Flagellar hook capping protein; flagellar basal body rod modification protein complement(3105326..3106021) Escherichia coli O104:H4 str. 2011C-3493 13701091 YP_006779717.1 CDS flgC NC_018658.1 3106033 3106437 R COG1558 Flagellar basal body rod protein; flagellar basal body rod protein FlgC complement(3106033..3106437) Escherichia coli O104:H4 str. 2011C-3493 13701092 YP_006779718.1 CDS flgB NC_018658.1 3106441 3106857 R COG1815 Flagellar basal body protein; flagellar basal body rod protein FlgB complement(3106441..3106857) Escherichia coli O104:H4 str. 2011C-3493 13701093 YP_006779719.1 CDS flgA NC_018658.1 3107012 3107671 D COG1261 Flagellar basal body P-ring biosynthesis protein; flagellar basal body P-ring biosynthesis protein FlgA 3107012..3107671 Escherichia coli O104:H4 str. 2011C-3493 13701094 YP_006779720.1 CDS O3K_15205 NC_018658.1 3107747 3108040 D COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor); anti-sigma-28 factor FlgM 3107747..3108040 Escherichia coli O104:H4 str. 2011C-3493 13701095 YP_006779721.1 CDS O3K_15210 NC_018658.1 3108045 3108461 D COG3418 Flagellar biosynthesis/type III secretory pathway chaperone; flagella synthesis chaperone protein FlgN 3108045..3108461 Escherichia coli O104:H4 str. 2011C-3493 13701096 YP_006779722.1 CDS O3K_15215 NC_018658.1 3108501 3110036 R COG0728 Uncharacterized membrane protein, putative virulence factor; putative inner membrane protein MviN complement(3108501..3110036) Escherichia coli O104:H4 str. 2011C-3493 13701097 YP_006779723.1 CDS O3K_15220 NC_018658.1 3110146 3111069 R COG0673 Predicted dehydrogenases and related proteins; oxidoreductase complement(3110146..3111069) Escherichia coli O104:H4 str. 2011C-3493 13701098 YP_006779724.1 CDS O3K_15225 NC_018658.1 3111071 3111718 R COG3132 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3111071..3111718) Escherichia coli O104:H4 str. 2011C-3493 13701099 YP_006779725.1 CDS O3K_15230 NC_018658.1 3111729 3112313 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-S5-alanine N-acetyltransferase complement(3111729..3112313) Escherichia coli O104:H4 str. 2011C-3493 13701100 YP_006779726.1 CDS O3K_15235 NC_018658.1 3112549 3113757 D COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein MdtH 3112549..3113757 Escherichia coli O104:H4 str. 2011C-3493 13701101 YP_006779727.1 CDS O3K_15240 NC_018658.1 3113821 3114468 D COG2999 Glutaredoxin 2; glutaredoxin 3113821..3114468 Escherichia coli O104:H4 str. 2011C-3493 13701102 YP_006779728.1 CDS O3K_15245 NC_018658.1 3114602 3115162 D lipoprotein 3114602..3115162 Escherichia coli O104:H4 str. 2011C-3493 13701103 YP_006779729.1 CDS O3K_15250 NC_018658.1 3115268 3116314 D COG0418 Dihydroorotase; dihydroorotase 3115268..3116314 Escherichia coli O104:H4 str. 2011C-3493 13701104 YP_006779730.1 CDS O3K_15255 NC_018658.1 3116388 3116633 D DNA damage-inducible protein I 3116388..3116633 Escherichia coli O104:H4 str. 2011C-3493 13701105 YP_006779731.1 CDS bssS NC_018658.1 3116923 3117177 D biofilm formation regulatory protein BssS 3116923..3117177 Escherichia coli O104:H4 str. 2011C-3493 13701106 YP_006779732.1 CDS solA NC_018658.1 3117292 3118410 D COG0665 Glycine/D-amino acid oxidases (deaminating); N-methyltryptophan oxidase 3117292..3118410 Escherichia coli O104:H4 str. 2011C-3493 13701107 YP_006779733.1 CDS O3K_15270 NC_018658.1 3118458 3118571 D hypothetical protein 3118458..3118571 Escherichia coli O104:H4 str. 2011C-3493 13701108 YP_006779734.1 CDS O3K_15275 NC_018658.1 3118832 3119398 D COG3038 Cytochrome B561; cytochrome 3118832..3119398 Escherichia coli O104:H4 str. 2011C-3493 13701109 YP_006779735.1 CDS O3K_15280 NC_018658.1 3119402 3119977 D COG2353 Uncharacterized conserved protein; hypothetical protein 3119402..3119977 Escherichia coli O104:H4 str. 2011C-3493 13701110 YP_006779736.1 CDS O3K_15285 NC_018658.1 3120019 3121071 R COG1054 Predicted sulfurtransferase; putative rhodanese-related sulfurtransferase complement(3120019..3121071) Escherichia coli O104:H4 str. 2011C-3493 13701111 YP_006779737.1 CDS O3K_15290 NC_018658.1 3121296 3122216 D COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis lauroyl acyltransferase 3121296..3122216 Escherichia coli O104:H4 str. 2011C-3493 13701112 YP_006779738.1 CDS O3K_15295 NC_018658.1 3122388 3123614 D COG0477 Permeases of the major facilitator superfamily; drug efflux system protein MdtG 3122388..3123614 Escherichia coli O104:H4 str. 2011C-3493 13701113 YP_006779739.1 CDS O3K_15300 NC_018658.1 3123697 3124071 D secY/secA suppressor protein 3123697..3124071 Escherichia coli O104:H4 str. 2011C-3493 13701114 YP_006779740.1 CDS O3K_15305 NC_018658.1 3124072 3124299 R COG5645 Predicted periplasmic lipoprotein; lipoprotein complement(3124072..3124299) Escherichia coli O104:H4 str. 2011C-3493 13701115 YP_006779741.1 CDS O3K_15310 NC_018658.1 3124472 3127015 R COG2943 Membrane glycosyltransferase; glucosyltransferase MdoH complement(3124472..3127015) Escherichia coli O104:H4 str. 2011C-3493 13701116 YP_006779742.1 CDS mdoG NC_018658.1 3127008 3128543 R COG3131 Periplasmic glucans biosynthesis protein; glucan biosynthesis protein G complement(3127008..3128543) Escherichia coli O104:H4 str. 2011C-3493 13701117 YP_006779743.1 CDS opgC NC_018658.1 3128937 3130094 D glucans biosynthesis protein 3128937..3130094 Escherichia coli O104:H4 str. 2011C-3493 13701118 YP_006779744.1 CDS O3K_15325 NC_018658.1 3130102 3131523 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phospholipase D/transphosphatidylase complement(3130102..3131523) Escherichia coli O104:H4 str. 2011C-3493 13701119 YP_006779745.1 CDS O3K_15330 NC_018658.1 3131525 3132058 R COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; RNase III inhibitor complement(3131525..3132058) Escherichia coli O104:H4 str. 2011C-3493 13701120 YP_006779746.1 CDS O3K_15335 NC_018658.1 3132153 3132353 R hypothetical protein complement(3132153..3132353) Escherichia coli O104:H4 str. 2011C-3493 13701121 YP_006779747.1 CDS csgC NC_018658.1 3132584 3132916 R curli assembly protein CsgC complement(3132584..3132916) Escherichia coli O104:H4 str. 2011C-3493 13701122 YP_006779748.1 CDS csgA NC_018658.1 3132975 3133430 R major curlin subunit complement(3132975..3133430) Escherichia coli O104:H4 str. 2011C-3493 13701123 YP_006779749.1 CDS csgB NC_018658.1 3133471 3133926 R curlin minor subunit CsgB complement(3133471..3133926) Escherichia coli O104:H4 str. 2011C-3493 13701124 YP_006779750.1 CDS O3K_15355 NC_018658.1 3134680 3135330 D COG2771 DNA-binding HTH domain-containing proteins; DNA-binding transcriptional regulator CsgD 3134680..3135330 Escherichia coli O104:H4 str. 2011C-3493 13701125 YP_006779751.1 CDS O3K_15360 NC_018658.1 3135335 3135724 D COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; curli assembly protein CsgE 3135335..3135724 Escherichia coli O104:H4 str. 2011C-3493 13701126 YP_006779752.1 CDS O3K_15365 NC_018658.1 3135749 3136165 D curli assembly protein CsgF 3135749..3136165 Escherichia coli O104:H4 str. 2011C-3493 13701127 YP_006779753.1 CDS O3K_15370 NC_018658.1 3136192 3137025 D COG1462 Uncharacterized protein involved in formation of curli polymers; curli production assembly/transport protein CsgG 3136192..3137025 Escherichia coli O104:H4 str. 2011C-3493 13701128 YP_006779754.1 CDS O3K_15375 NC_018658.1 3137089 3137580 R inner membrane protein complement(3137089..3137580) Escherichia coli O104:H4 str. 2011C-3493 13701129 YP_006779755.1 CDS O3K_15380 NC_018658.1 3137682 3138236 R COG3381 Uncharacterized component of anaerobic dehydrogenases; hypothetical protein complement(3137682..3138236) Escherichia coli O104:H4 str. 2011C-3493 13701130 YP_006779756.1 CDS O3K_15385 NC_018658.1 3138260 3138997 R COG1387 Histidinol phosphatase and related hydrolases of the PHP family; hydrolase complement(3138260..3138997) Escherichia coli O104:H4 str. 2011C-3493 13701131 YP_006779757.1 CDS ghrA NC_018658.1 3139052 3139990 R COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; bifunctional glyoxylate/hydroxypyruvate reductase A complement(3139052..3139990) Escherichia coli O104:H4 str. 2011C-3493 13701132 YP_006779758.1 CDS O3K_15395 NC_018658.1 3140461 3141303 R hypothetical protein complement(3140461..3141303) Escherichia coli O104:H4 str. 2011C-3493 13701134 YP_006779759.1 CDS O3K_15400 NC_018658.1 3141388 3141585 R hypothetical protein complement(3141388..3141585) Escherichia coli O104:H4 str. 2011C-3493 13701135 YP_006779760.1 CDS O3K_15405 NC_018658.1 3141597 3142085 R hypothetical protein complement(3141597..3142085) Escherichia coli O104:H4 str. 2011C-3493 13701136 YP_006779761.1 CDS O3K_15410 NC_018658.1 3142085 3142459 R hypothetical protein complement(3142085..3142459) Escherichia coli O104:H4 str. 2011C-3493 13701137 YP_006779762.1 CDS O3K_15415 NC_018658.1 3142550 3142903 R CP4-44 prophage YeeV-YeeU toxin-antitoxin system toxin complement(3142550..3142903) Escherichia coli O104:H4 str. 2011C-3493 13701138 YP_006779763.1 CDS O3K_15420 NC_018658.1 3142979 3143200 R hypothetical protein complement(3142979..3143200) Escherichia coli O104:H4 str. 2011C-3493 13701139 YP_006779764.1 CDS O3K_15425 NC_018658.1 3143263 3143739 R COG2003 DNA repair proteins; radC-like protein YeeS complement(3143263..3143739) Escherichia coli O104:H4 str. 2011C-3493 13701140 YP_006779765.1 CDS O3K_15430 NC_018658.1 3143755 3144228 R hypothetical protein complement(3143755..3144228) Escherichia coli O104:H4 str. 2011C-3493 13701141 YP_006779766.1 CDS O3K_15435 NC_018658.1 3144322 3144567 R hypothetical protein complement(3144322..3144567) Escherichia coli O104:H4 str. 2011C-3493 13701142 YP_006779767.1 CDS O3K_15440 NC_018658.1 3144567 3145388 R hypothetical protein complement(3144567..3145388) Escherichia coli O104:H4 str. 2011C-3493 13701143 YP_006779768.1 CDS O3K_15445 NC_018658.1 3145609 3146019 R hypothetical protein complement(3145609..3146019) Escherichia coli O104:H4 str. 2011C-3493 13701144 YP_006779769.1 CDS O3K_15450 NC_018658.1 3146035 3146718 R hypothetical protein complement(3146035..3146718) Escherichia coli O104:H4 str. 2011C-3493 13701145 YP_006779770.1 CDS O3K_15455 NC_018658.1 3146852 3147922 R COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein complement(3146852..3147922) Escherichia coli O104:H4 str. 2011C-3493 13701146 YP_006779771.1 CDS O3K_15460 NC_018658.1 3147919 3148824 R hypothetical protein complement(3147919..3148824) Escherichia coli O104:H4 str. 2011C-3493 13701147 YP_006779772.1 CDS O3K_15465 NC_018658.1 3148821 3151217 R COG0699 Predicted GTPases (dynamin-related); hypothetical protein complement(3148821..3151217) Escherichia coli O104:H4 str. 2011C-3493 13701148 YP_006779773.1 CDS O3K_15485 NC_018658.1 3153689 3154561 R COG3596 Predicted GTPase; GTP-binding protein complement(3153689..3154561) Escherichia coli O104:H4 str. 2011C-3493 13701149 YP_006779774.1 CDS O3K_15490 NC_018658.1 3155373 3155798 R COG2963 Transposase and inactivated derivatives; IS66 transposase complement(3155373..3155798) Escherichia coli O104:H4 str. 2011C-3493 13701150 YP_006779775.1 CDS O3K_15495 NC_018658.1 3155956 3157197 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein TerF complement(3155956..3157197) Escherichia coli O104:H4 str. 2011C-3493 13701151 YP_006779776.1 CDS O3K_15500 NC_018658.1 3157629 3158204 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; putative tellurium resistance protein TerE complement(3157629..3158204) Escherichia coli O104:H4 str. 2011C-3493 13701152 YP_006779777.1 CDS O3K_15505 NC_018658.1 3158273 3158851 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein complement(3158273..3158851) Escherichia coli O104:H4 str. 2011C-3493 13701153 YP_006779778.1 CDS O3K_15510 NC_018658.1 3158900 3159940 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; Tellurium resistance protein TerC complement(3158900..3159940) Escherichia coli O104:H4 str. 2011C-3493 13701154 YP_006779779.1 CDS O3K_15515 NC_018658.1 3159963 3160418 R COG3793 Tellurite resistance protein; putative tellurium resistance protein TerB complement(3159963..3160418) Escherichia coli O104:H4 str. 2011C-3493 13701155 YP_006779780.1 CDS O3K_15520 NC_018658.1 3160441 3161598 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; putative tellurium resistance protein TerA complement(3160441..3161598) Escherichia coli O104:H4 str. 2011C-3493 13701156 YP_006779781.1 CDS O3K_15525 NC_018658.1 3161598 3162179 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein complement(3161598..3162179) Escherichia coli O104:H4 str. 2011C-3493 13701157 YP_006779782.1 CDS O3K_15530 NC_018658.1 3162502 3163560 D COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein 3162502..3163560 Escherichia coli O104:H4 str. 2011C-3493 13701158 YP_006779783.1 CDS O3K_15535 NC_018658.1 3163570 3164712 D hypothetical protein 3163570..3164712 Escherichia coli O104:H4 str. 2011C-3493 13701159 YP_006779784.1 CDS O3K_15540 NC_018658.1 3164705 3165478 D COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 3164705..3165478 Escherichia coli O104:H4 str. 2011C-3493 13701160 YP_006779785.1 CDS O3K_15545 NC_018658.1 3165480 3166559 D putative ATP-binding protein 3165480..3166559 Escherichia coli O104:H4 str. 2011C-3493 13701161 YP_006779786.1 CDS O3K_15550 NC_018658.1 3166559 3167515 D COG2301 Citrate lyase beta subunit; hypothetical protein 3166559..3167515 Escherichia coli O104:H4 str. 2011C-3493 13701162 YP_006779787.1 CDS O3K_15555 NC_018658.1 3167526 3168734 D hypothetical protein 3167526..3168734 Escherichia coli O104:H4 str. 2011C-3493 13701163 YP_006779788.1 CDS O3K_15560 NC_018658.1 3168752 3169219 D putative tellurium resistance protein TerW 3168752..3169219 Escherichia coli O104:H4 str. 2011C-3493 13701164 YP_006779789.1 CDS O3K_15565 NC_018658.1 3169389 3169520 R hypothetical protein complement(3169389..3169520) Escherichia coli O104:H4 str. 2011C-3493 13701165 YP_006779790.1 CDS O3K_15570 NC_018658.1 3169683 3170321 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY1 3169683..3170321 Escherichia coli O104:H4 str. 2011C-3493 13701166 YP_006779791.1 CDS O3K_15575 NC_018658.1 3170344 3170982 D COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein terX 3170344..3170982 Escherichia coli O104:H4 str. 2011C-3493 13701167 YP_006779792.1 CDS O3K_15580 NC_018658.1 3170982 3171620 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY2 3170982..3171620 Escherichia coli O104:H4 str. 2011C-3493 13701168 YP_006779793.1 CDS O3K_15585 NC_018658.1 3171705 3172745 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY3 3171705..3172745 Escherichia coli O104:H4 str. 2011C-3493 13701169 YP_006779794.1 CDS O3K_15590 NC_018658.1 3172745 3174382 D hypothetical protein 3172745..3174382 Escherichia coli O104:H4 str. 2011C-3493 13701170 YP_006779795.1 CDS O3K_15595 NC_018658.1 3174408 3175907 D COG0515 Serine/threonine protein kinase; protein kinase 3174408..3175907 Escherichia coli O104:H4 str. 2011C-3493 13701171 YP_006779796.1 CDS O3K_15600 NC_018658.1 3175995 3176663 D COG4584 Transposase and inactivated derivatives; transposase 3175995..3176663 Escherichia coli O104:H4 str. 2011C-3493 13701172 YP_006779797.1 CDS O3K_15605 NC_018658.1 3176738 3176923 D COG1484 DNA replication protein; IS100 transposase 3176738..3176923 Escherichia coli O104:H4 str. 2011C-3493 13701173 YP_006779798.1 CDS O3K_15610 NC_018658.1 3177492 3177668 D hypothetical protein 3177492..3177668 Escherichia coli O104:H4 str. 2011C-3493 13701175 YP_006779799.1 CDS O3K_15615 NC_018658.1 3178288 3178533 D COG1943 Transposase and inactivated derivatives; transposase IS605 family, IS200 group 3178288..3178533 Escherichia coli O104:H4 str. 2011C-3493 13701176 YP_006779800.1 CDS O3K_15620 NC_018658.1 3178651 3179589 R COG0583 Transcriptional regulator; cell density-dependent motility repressor complement(3178651..3179589) Escherichia coli O104:H4 str. 2011C-3493 13701177 YP_006779801.1 CDS O3K_15625 NC_018658.1 3179940 3180659 D COG1794 Aspartate racemase; aspartate racemase 3179940..3180659 Escherichia coli O104:H4 str. 2011C-3493 13701178 YP_006779802.1 CDS O3K_15630 NC_018658.1 3180725 3182023 D COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 3180725..3182023 Escherichia coli O104:H4 str. 2011C-3493 13701179 YP_006779803.1 CDS O3K_15635 NC_018658.1 3182267 3182980 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(3182267..3182980) Escherichia coli O104:H4 str. 2011C-3493 13701180 YP_006779804.1 CDS O3K_15640 NC_018658.1 3183065 3183274 R COG1662 Transposase and inactivated derivatives, IS1 family; insertion element protein complement(3183065..3183274) Escherichia coli O104:H4 str. 2011C-3493 13701181 YP_006779805.1 CDS O3K_15645 NC_018658.1 3183275 3183568 R IS1; transposase ORF B, IS1 complement(3183275..3183568) Escherichia coli O104:H4 str. 2011C-3493 13701182 YP_006779806.1 CDS O3K_15650 NC_018658.1 3183487 3183762 R COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA complement(3183487..3183762) Escherichia coli O104:H4 str. 2011C-3493 13701183 YP_006779807.1 CDS O3K_15655 NC_018658.1 3183791 3183910 R hypothetical protein complement(3183791..3183910) Escherichia coli O104:H4 str. 2011C-3493 13701184 YP_006779808.1 CDS O3K_15660 NC_018658.1 3184030 3185127 R COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase; hypothetical protein complement(3184030..3185127) Escherichia coli O104:H4 str. 2011C-3493 13701185 YP_006779809.1 CDS O3K_15665 NC_018658.1 3185636 3187855 R COG1112 Superfamily I DNA and RNA helicases and helicase subunits; putative UvrD/REP helicase-like protein complement(3185636..3187855) Escherichia coli O104:H4 str. 2011C-3493 13701186 YP_006779810.1 CDS O3K_15670 NC_018658.1 3188559 3189134 R hypothetical protein complement(3188559..3189134) Escherichia coli O104:H4 str. 2011C-3493 13701187 YP_006779811.1 CDS O3K_15675 NC_018658.1 3190109 3190342 R hypothetical protein complement(3190109..3190342) Escherichia coli O104:H4 str. 2011C-3493 13701188 YP_006779812.1 CDS O3K_15680 NC_018658.1 3190438 3191061 R hypothetical protein complement(3190438..3191061) Escherichia coli O104:H4 str. 2011C-3493 13701189 YP_006779813.1 CDS O3K_15685 NC_018658.1 3193004 3193360 D COG1266 Predicted metal-dependent membrane protease; hypothetical protein 3193004..3193360 Escherichia coli O104:H4 str. 2011C-3493 13701190 YP_006779814.1 CDS O3K_15690 NC_018658.1 3194356 3196458 R COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; colicin V secretion/processing ATP binding protein complement(3194356..3196458) Escherichia coli O104:H4 str. 2011C-3493 13701191 YP_006779815.1 CDS O3K_15695 NC_018658.1 3196451 3197638 R COG0845 Membrane-fusion protein; Colicin V secretion protein CvaA complement(3196451..3197638) Escherichia coli O104:H4 str. 2011C-3493 13701192 YP_006779816.1 CDS O3K_15700 NC_018658.1 3197878 3198330 R COG2994 ACP:hemolysin acyltransferase (hemolysin-activating protein); hypothetical protein complement(3197878..3198330) Escherichia coli O104:H4 str. 2011C-3493 13701193 YP_006779817.1 CDS O3K_15705 NC_018658.1 3198356 3199906 R hypothetical protein complement(3198356..3199906) Escherichia coli O104:H4 str. 2011C-3493 13701194 YP_006779818.1 CDS O3K_15710 NC_018658.1 3201455 3201889 D COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); hypothetical protein 3201455..3201889 Escherichia coli O104:H4 str. 2011C-3493 13701195 YP_006779819.1 CDS O3K_15715 NC_018658.1 3202042 3203022 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 3202042..3203022 Escherichia coli O104:H4 str. 2011C-3493 13701196 YP_006779820.1 CDS O3K_15720 NC_018658.1 3204058 3204285 R hypothetical protein complement(3204058..3204285) Escherichia coli O104:H4 str. 2011C-3493 13701197 YP_006779821.1 CDS O3K_15725 NC_018658.1 3204321 3204902 D COG2382 Enterochelin esterase and related enzymes; ferric enterochelin esterase 3204321..3204902 Escherichia coli O104:H4 str. 2011C-3493 13701198 YP_006779822.1 CDS O3K_15730 NC_018658.1 3205044 3206168 R COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; putative glucosyl-transferase complement(3205044..3206168) Escherichia coli O104:H4 str. 2011C-3493 13701199 YP_006779823.1 CDS O3K_15735 NC_018658.1 3206898 3207095 R COG3311 Predicted transcriptional regulator; putative DNA binding protein complement(3206898..3207095) Escherichia coli O104:H4 str. 2011C-3493 13701200 YP_006779824.1 CDS O3K_15740 NC_018658.1 3207161 3207355 R hypothetical protein complement(3207161..3207355) Escherichia coli O104:H4 str. 2011C-3493 13701201 YP_006779825.1 CDS O3K_15745 NC_018658.1 3207577 3207660 D hypothetical protein 3207577..3207660 Escherichia coli O104:H4 str. 2011C-3493 13701202 YP_006779826.1 CDS O3K_15750 NC_018658.1 3208257 3208451 D hypothetical protein 3208257..3208451 Escherichia coli O104:H4 str. 2011C-3493 13701203 YP_006779827.1 CDS O3K_15755 NC_018658.1 3208812 3208940 D COG2801 Transposase and inactivated derivatives; hypothetical protein 3208812..3208940 Escherichia coli O104:H4 str. 2011C-3493 13701204 YP_006779828.1 CDS O3K_15760 NC_018658.1 3209422 3209586 R hypothetical protein complement(3209422..3209586) Escherichia coli O104:H4 str. 2011C-3493 13701205 YP_006779829.1 CDS O3K_15765 NC_018658.1 3210220 3210438 R hypothetical protein complement(3210220..3210438) Escherichia coli O104:H4 str. 2011C-3493 13701206 YP_006779830.1 CDS O3K_15770 NC_018658.1 3211770 3211952 R hypothetical protein complement(3211770..3211952) Escherichia coli O104:H4 str. 2011C-3493 13701207 YP_006779831.1 CDS O3K_15775 NC_018658.1 3211891 3213981 D COG4771 Outer membrane receptor for ferrienterochelin and colicins; bifunctional enterobactin receptor/adhesin protein 3211891..3213981 Escherichia coli O104:H4 str. 2011C-3493 13701208 YP_006779832.1 CDS O3K_15780 NC_018658.1 3214215 3214439 D hypothetical protein 3214215..3214439 Escherichia coli O104:H4 str. 2011C-3493 13701209 YP_006779833.1 CDS O3K_15785 NC_018658.1 3214677 3215081 D COG2963 Transposase and inactivated derivatives; ISSfl3 protein 3214677..3215081 Escherichia coli O104:H4 str. 2011C-3493 13701210 YP_006779834.1 CDS O3K_15790 NC_018658.1 3215078 3215425 D COG3436 Transposase and inactivated derivatives; IS66 family element 3215078..3215425 Escherichia coli O104:H4 str. 2011C-3493 13701211 YP_006779835.1 CDS O3K_15805 NC_018658.1 3216669 3216857 D hypothetical protein 3216669..3216857 Escherichia coli O104:H4 str. 2011C-3493 13701212 YP_006779836.1 CDS O3K_15810 NC_018658.1 3216875 3219235 R COG4951 Uncharacterized protein conserved in bacteria; helicase complement(3216875..3219235) Escherichia coli O104:H4 str. 2011C-3493 13701213 YP_006779837.1 CDS O3K_15815 NC_018658.1 3219390 3219953 R hypothetical protein complement(3219390..3219953) Escherichia coli O104:H4 str. 2011C-3493 13701214 YP_006779838.1 CDS O3K_15820 NC_018658.1 3221289 3223124 R hypothetical protein complement(3221289..3223124) Escherichia coli O104:H4 str. 2011C-3493 13701215 YP_006779839.1 CDS O3K_15825 NC_018658.1 3223225 3223512 D COG3311 Predicted transcriptional regulator; putative regulatory protein 3223225..3223512 Escherichia coli O104:H4 str. 2011C-3493 13701216 YP_006779840.1 CDS O3K_15830 NC_018658.1 3223487 3225013 D hypothetical protein 3223487..3225013 Escherichia coli O104:H4 str. 2011C-3493 13701217 YP_006779841.1 CDS O3K_15835 NC_018658.1 3225183 3226400 R COG0582 Integrase; integrase complement(3225183..3226400) Escherichia coli O104:H4 str. 2011C-3493 13701218 YP_006779842.1 CDS O3K_15840 NC_018658.1 3226948 3227934 R inner membrane protein complement(3226948..3227934) Escherichia coli O104:H4 str. 2011C-3493 13701219 YP_006779843.1 CDS O3K_15845 NC_018658.1 3227931 3228422 R COG0331 (acyl-carrier-protein) S-malonyltransferase; hypothetical protein complement(3227931..3228422) Escherichia coli O104:H4 str. 2011C-3493 13701220 YP_006779844.1 CDS O3K_15850 NC_018658.1 3228525 3228824 D COG2963 Transposase and inactivated derivatives; IS3 element protein InsE 3228525..3228824 Escherichia coli O104:H4 str. 2011C-3493 13701221 YP_006779845.1 CDS O3K_15855 NC_018658.1 3228821 3229687 D COG2801 Transposase and inactivated derivatives; transposase 3228821..3229687 Escherichia coli O104:H4 str. 2011C-3493 13701222 YP_006779846.1 CDS O3K_15860 NC_018658.1 3229728 3231086 R COG2199 FOG: GGDEF domain; diguanylate cyclase complement(3229728..3231086) Escherichia coli O104:H4 str. 2011C-3493 13701223 YP_006779847.1 CDS pgaA NC_018658.1 3231673 3234096 D COG0457 FOG: TPR repeat; outer membrane protein PgaA 3231673..3234096 Escherichia coli O104:H4 str. 2011C-3493 13701224 YP_006779848.1 CDS pgaB NC_018658.1 3234105 3236123 D COG0726 Predicted xylanase/chitin deacetylase; outer membrane N-deacetylase 3234105..3236123 Escherichia coli O104:H4 str. 2011C-3493 13701225 YP_006779849.1 CDS O3K_15875 NC_018658.1 3236116 3237441 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; N-glycosyltransferase 3236116..3237441 Escherichia coli O104:H4 str. 2011C-3493 13701226 YP_006779850.1 CDS pgaD NC_018658.1 3237443 3237856 D putative PGA biosynthesis protein 3237443..3237856 Escherichia coli O104:H4 str. 2011C-3493 13701227 YP_006779851.1 CDS O3K_15885 NC_018658.1 3237906 3238694 R COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; hypothetical protein complement(3237906..3238694) Escherichia coli O104:H4 str. 2011C-3493 13701228 YP_006779852.1 CDS O3K_15890 NC_018658.1 3239313 3240584 R COG2837 Predicted iron-dependent peroxidase; hypothetical protein complement(3239313..3240584) Escherichia coli O104:H4 str. 2011C-3493 13701229 YP_006779853.1 CDS O3K_15895 NC_018658.1 3240590 3241717 R COG2822 Predicted periplasmic lipoprotein involved in iron transport; inactive ferrous ion transporter periplasmic protein EfeO complement(3240590..3241717) Escherichia coli O104:H4 str. 2011C-3493 13701230 YP_006779854.1 CDS O3K_15900 NC_018658.1 3241775 3242605 R COG0672 High-affinity Fe2+/Pb2+ permease; putative high-affinity Fe2+/Pb2+ permease complement(3241775..3242605) Escherichia coli O104:H4 str. 2011C-3493 13701231 YP_006779855.1 CDS O3K_15905 NC_018658.1 3243147 3244655 R COG0591 Na+/proline symporter; proline:sodium symporter PutP complement(3243147..3244655) Escherichia coli O104:H4 str. 2011C-3493 13701232 YP_006779856.1 CDS O3K_15910 NC_018658.1 3244814 3245023 R hypothetical protein complement(3244814..3245023) Escherichia coli O104:H4 str. 2011C-3493 13701233 YP_006779857.1 CDS putA NC_018658.1 3245078 3249040 D COG0506 Proline dehydrogenase; multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 3245078..3249040 Escherichia coli O104:H4 str. 2011C-3493 13701234 YP_006779858.1 CDS O3K_15920 NC_018658.1 3249080 3249718 R COG1309 Transcriptional regulator; HTH-type transcriptional regulator RutR complement(3249080..3249718) Escherichia coli O104:H4 str. 2011C-3493 13701235 YP_006779859.1 CDS O3K_15925 NC_018658.1 3250006 3251097 D COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; monooxygenase of the alternative pyrimidine degradation pathway 3250006..3251097 Escherichia coli O104:H4 str. 2011C-3493 13701236 YP_006779860.1 CDS O3K_15930 NC_018658.1 3251097 3251789 D COG1335 Amidases related to nicotinamidase; hypothetical protein 3251097..3251789 Escherichia coli O104:H4 str. 2011C-3493 13701237 YP_006779861.1 CDS O3K_15935 NC_018658.1 3251801 3252187 D COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 3251801..3252187 Escherichia coli O104:H4 str. 2011C-3493 13701238 YP_006779862.1 CDS O3K_15940 NC_018658.1 3252195 3252995 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); enzyme of the alternative pyrimidine degradation pathway 3252195..3252995 Escherichia coli O104:H4 str. 2011C-3493 13701239 YP_006779863.1 CDS O3K_15945 NC_018658.1 3253005 3253595 D COG0778 Nitroreductase; malonic semialdehyde reductase 3253005..3253595 Escherichia coli O104:H4 str. 2011C-3493 13701240 YP_006779864.1 CDS O3K_15950 NC_018658.1 3253606 3254100 D COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; flavin:NADH oxidoreductase subunit of alternative pyrimidine degradation pathway 3253606..3254100 Escherichia coli O104:H4 str. 2011C-3493 13701241 YP_006779865.1 CDS O3K_15955 NC_018658.1 3254121 3255449 D COG2233 Xanthine/uracil permeases; transporter 3254121..3255449 Escherichia coli O104:H4 str. 2011C-3493 13701242 YP_006779866.1 CDS O3K_15960 NC_018658.1 3255532 3255705 R COG3729 General stress protein; hypothetical protein complement(3255532..3255705) Escherichia coli O104:H4 str. 2011C-3493 13701243 YP_006779868.1 CDS O3K_15970 NC_018658.1 3256637 3265018 R hypothetical protein complement(3256637..3265018) Escherichia coli O104:H4 str. 2011C-3493 13701245 YP_006779869.1 CDS O3K_15975 NC_018658.1 3265088 3266353 R hypothetical protein complement(3265088..3266353) Escherichia coli O104:H4 str. 2011C-3493 13701246 YP_006779870.1 CDS O3K_15980 NC_018658.1 3266364 3266615 R hypothetical protein complement(3266364..3266615) Escherichia coli O104:H4 str. 2011C-3493 13701247 YP_006779871.1 CDS O3K_15985 NC_018658.1 3266625 3267071 R hypothetical protein complement(3266625..3267071) Escherichia coli O104:H4 str. 2011C-3493 13701248 YP_006779872.1 CDS O3K_15990 NC_018658.1 3267074 3267730 R hypothetical protein complement(3267074..3267730) Escherichia coli O104:H4 str. 2011C-3493 13701249 YP_006779873.1 CDS O3K_15995 NC_018658.1 3267824 3268225 R hypothetical protein complement(3267824..3268225) Escherichia coli O104:H4 str. 2011C-3493 13701250 YP_006779874.1 CDS O3K_16000 NC_018658.1 3268282 3268422 R hypothetical protein complement(3268282..3268422) Escherichia coli O104:H4 str. 2011C-3493 13701251 YP_006779875.1 CDS O3K_16005 NC_018658.1 3268655 3269389 R putative outer membrane protein Lom complement(3268655..3269389) Escherichia coli O104:H4 str. 2011C-3493 13701252 YP_006779876.1 CDS O3K_16010 NC_018658.1 3269480 3270097 R hypothetical protein complement(3269480..3270097) Escherichia coli O104:H4 str. 2011C-3493 13701253 YP_006779877.1 CDS O3K_16015 NC_018658.1 3270103 3270381 R putative outer membrane protein complement(3270103..3270381) Escherichia coli O104:H4 str. 2011C-3493 13701254 YP_006779878.1 CDS O3K_16020 NC_018658.1 3270396 3271664 R COG4733 Phage-related protein, tail component; putative tail tip fiber protein complement(3270396..3271664) Escherichia coli O104:H4 str. 2011C-3493 13701255 YP_006779879.1 CDS O3K_16025 NC_018658.1 3271661 3273352 R hypothetical protein complement(3271661..3273352) Escherichia coli O104:H4 str. 2011C-3493 13701256 YP_006779880.1 CDS O3K_16030 NC_018658.1 3273520 3274032 R hypothetical protein complement(3273520..3274032) Escherichia coli O104:H4 str. 2011C-3493 13701257 YP_006779881.1 CDS O3K_16035 NC_018658.1 3274119 3276311 R putative tail fiber protein complement(3274119..3276311) Escherichia coli O104:H4 str. 2011C-3493 13701258 YP_006779882.1 CDS O3K_16040 NC_018658.1 3276308 3276958 R hypothetical protein complement(3276308..3276958) Escherichia coli O104:H4 str. 2011C-3493 13701259 YP_006779883.1 CDS O3K_16045 NC_018658.1 3276958 3277521 R hypothetical protein complement(3276958..3277521) Escherichia coli O104:H4 str. 2011C-3493 13701260 YP_006779884.1 CDS O3K_16050 NC_018658.1 3277505 3277966 R hypothetical protein complement(3277505..3277966) Escherichia coli O104:H4 str. 2011C-3493 13701261 YP_006779885.1 CDS O3K_16055 NC_018658.1 3278016 3278405 R hypothetical protein complement(3278016..3278405) Escherichia coli O104:H4 str. 2011C-3493 13701262 YP_006779886.1 CDS O3K_16060 NC_018658.1 3278461 3279675 R hypothetical protein complement(3278461..3279675) Escherichia coli O104:H4 str. 2011C-3493 13701263 YP_006779887.1 CDS O3K_16065 NC_018658.1 3279699 3280706 R hypothetical protein complement(3279699..3280706) Escherichia coli O104:H4 str. 2011C-3493 13701264 YP_006779888.1 CDS O3K_16070 NC_018658.1 3280864 3283008 R putative portal protein complement(3280864..3283008) Escherichia coli O104:H4 str. 2011C-3493 13701265 YP_006779889.1 CDS O3K_16075 NC_018658.1 3283008 3284714 R terminase large subunit complement(3283008..3284714) Escherichia coli O104:H4 str. 2011C-3493 13701266 YP_006779890.1 CDS O3K_16080 NC_018658.1 3284695 3285501 R putative small subunit terminase complement(3284695..3285501) Escherichia coli O104:H4 str. 2011C-3493 13701267 YP_006779891.1 CDS O3K_16085 NC_018658.1 3285794 3286345 R COG3646 Uncharacterized phage-encoded protein; putative phage protein Rha complement(3285794..3286345) Escherichia coli O104:H4 str. 2011C-3493 13701268 YP_006779892.1 CDS O3K_16090 NC_018658.1 3286548 3286976 R endopeptidase (Protein gp15) complement(3286548..3286976) Escherichia coli O104:H4 str. 2011C-3493 13701269 YP_006779893.1 CDS O3K_16095 NC_018658.1 3286988 3287122 R hypothetical protein complement(3286988..3287122) Escherichia coli O104:H4 str. 2011C-3493 13701270 YP_006779894.1 CDS O3K_16100 NC_018658.1 3287137 3287706 R putative antirepressor complement(3287137..3287706) Escherichia coli O104:H4 str. 2011C-3493 13701271 YP_006779895.1 CDS O3K_16105 NC_018658.1 3287980 3288513 R COG3772 Phage-related lysozyme (muraminidase); putative endolysin complement(3287980..3288513) Escherichia coli O104:H4 str. 2011C-3493 13701272 YP_006779896.1 CDS O3K_16110 NC_018658.1 3288518 3288733 R lysis protein complement(3288518..3288733) Escherichia coli O104:H4 str. 2011C-3493 13701273 YP_006779897.1 CDS O3K_16115 NC_018658.1 3288811 3289056 R hypothetical protein complement(3288811..3289056) Escherichia coli O104:H4 str. 2011C-3493 13701274 YP_006779898.1 CDS O3K_16120 NC_018658.1 3289097 3289276 R hypothetical protein complement(3289097..3289276) Escherichia coli O104:H4 str. 2011C-3493 13701275 YP_006779899.1 CDS O3K_16125 NC_018658.1 3289413 3291350 R hypothetical protein complement(3289413..3291350) Escherichia coli O104:H4 str. 2011C-3493 13701276 YP_006779900.1 CDS O3K_16130 NC_018658.1 3291836 3292105 R Shiga toxin 2 subunit B complement(3291836..3292105) Escherichia coli O104:H4 str. 2011C-3493 13701277 YP_006779901.1 CDS O3K_16135 NC_018658.1 3292117 3293076 R Shiga toxin 2 subunit A complement(3292117..3293076) Escherichia coli O104:H4 str. 2011C-3493 13701278 YP_006779902.1 CDS O3K_16140 NC_018658.1 3293459 3293557 R DNA adenine methyltransferase encoded by prophage complement(3293459..3293557) Escherichia coli O104:H4 str. 2011C-3493 13701282 YP_006779903.1 CDS O3K_16145 NC_018658.1 3293860 3294294 R putative antitermination protein Q complement(3293860..3294294) Escherichia coli O104:H4 str. 2011C-3493 13701283 YP_006779904.1 CDS O3K_16150 NC_018658.1 3294287 3294481 R hypothetical protein complement(3294287..3294481) Escherichia coli O104:H4 str. 2011C-3493 13701284 YP_006779905.1 CDS O3K_16155 NC_018658.1 3294478 3295041 R hypothetical protein complement(3294478..3295041) Escherichia coli O104:H4 str. 2011C-3493 13701285 YP_006779906.1 CDS O3K_16160 NC_018658.1 3295049 3295498 R hypothetical protein complement(3295049..3295498) Escherichia coli O104:H4 str. 2011C-3493 13701286 YP_006779907.1 CDS O3K_16165 NC_018658.1 3295498 3296469 R DNA primase complement(3295498..3296469) Escherichia coli O104:H4 str. 2011C-3493 13701287 YP_006779908.1 CDS O3K_16170 NC_018658.1 3296459 3297979 R COG1061 DNA or RNA helicases of superfamily II; helicase complement(3296459..3297979) Escherichia coli O104:H4 str. 2011C-3493 13701288 YP_006779909.1 CDS O3K_16175 NC_018658.1 3297973 3298350 R COG3480 Predicted secreted protein containing a PDZ domain; hypothetical protein complement(3297973..3298350) Escherichia coli O104:H4 str. 2011C-3493 13701289 YP_006779910.1 CDS O3K_16180 NC_018658.1 3298558 3298851 R hypothetical protein complement(3298558..3298851) Escherichia coli O104:H4 str. 2011C-3493 13701290 YP_006779911.1 CDS O3K_16185 NC_018658.1 3298882 3299085 R hypothetical protein complement(3298882..3299085) Escherichia coli O104:H4 str. 2011C-3493 13701291 YP_006779912.1 CDS O3K_16190 NC_018658.1 3299181 3299894 D COG2932 Predicted transcriptional regulator; repressor protein CI 3299181..3299894 Escherichia coli O104:H4 str. 2011C-3493 13701292 YP_006779913.1 CDS O3K_16195 NC_018658.1 3299989 3301458 D COG0286 Type I restriction-modification system methyltransferase subunit; site-specific DNA-methyltransferase 3299989..3301458 Escherichia coli O104:H4 str. 2011C-3493 13701293 YP_006779914.1 CDS O3K_16200 NC_018658.1 3301455 3302408 D type II site-specific deoxyribonuclease 3301455..3302408 Escherichia coli O104:H4 str. 2011C-3493 13701294 YP_006779915.1 CDS O3K_16205 NC_018658.1 3303037 3303810 D COG3646 Uncharacterized phage-encoded protein; hypothetical protein 3303037..3303810 Escherichia coli O104:H4 str. 2011C-3493 13701295 YP_006779916.1 CDS O3K_16210 NC_018658.1 3304267 3304740 D anti-termination protein 3304267..3304740 Escherichia coli O104:H4 str. 2011C-3493 13701296 YP_006779917.1 CDS O3K_16215 NC_018658.1 3304811 3305023 D host killing protein 3304811..3305023 Escherichia coli O104:H4 str. 2011C-3493 13701297 YP_006779918.1 CDS O3K_16220 NC_018658.1 3305095 3305316 D hypothetical protein 3305095..3305316 Escherichia coli O104:H4 str. 2011C-3493 13701298 YP_006779919.1 CDS O3K_16225 NC_018658.1 3305337 3305618 D hypothetical protein 3305337..3305618 Escherichia coli O104:H4 str. 2011C-3493 13701299 YP_006779920.1 CDS O3K_16230 NC_018658.1 3305635 3306585 D COG3723 Recombinational DNA repair protein (RecE pathway); DNA recombination protein Bet 3305635..3306585 Escherichia coli O104:H4 str. 2011C-3493 13701300 YP_006779921.1 CDS O3K_16235 NC_018658.1 3306582 3307271 D COG4615 ABC-type siderophore export system, fused ATPase and permease components; exonuclease 3306582..3307271 Escherichia coli O104:H4 str. 2011C-3493 13701301 YP_006779922.1 CDS O3K_16240 NC_018658.1 3307271 3307858 D hypothetical protein 3307271..3307858 Escherichia coli O104:H4 str. 2011C-3493 13701302 YP_006779923.1 CDS O3K_16245 NC_018658.1 3307933 3308280 D hypothetical protein 3307933..3308280 Escherichia coli O104:H4 str. 2011C-3493 13701303 YP_006779924.1 CDS O3K_16250 NC_018658.1 3308344 3309165 D COG5532 Uncharacterized conserved protein; hypothetical protein 3308344..3309165 Escherichia coli O104:H4 str. 2011C-3493 13701304 YP_006779925.1 CDS O3K_16255 NC_018658.1 3309242 3309637 D hypothetical protein 3309242..3309637 Escherichia coli O104:H4 str. 2011C-3493 13701305 YP_006779926.1 CDS O3K_16260 NC_018658.1 3309788 3310513 D hypothetical protein 3309788..3310513 Escherichia coli O104:H4 str. 2011C-3493 13701306 YP_006779927.1 CDS O3K_16265 NC_018658.1 3310510 3310917 D hypothetical protein 3310510..3310917 Escherichia coli O104:H4 str. 2011C-3493 13701307 YP_006779928.1 CDS O3K_16270 NC_018658.1 3310919 3311110 D hypothetical protein 3310919..3311110 Escherichia coli O104:H4 str. 2011C-3493 13701308 YP_006779929.1 CDS O3K_16275 NC_018658.1 3311113 3312009 D hypothetical protein 3311113..3312009 Escherichia coli O104:H4 str. 2011C-3493 13701309 YP_006779930.1 CDS O3K_16280 NC_018658.1 3312002 3312100 D hypothetical protein 3312002..3312100 Escherichia coli O104:H4 str. 2011C-3493 13701310 YP_006779931.1 CDS O3K_16285 NC_018658.1 3312365 3313003 D COG3561 Phage anti-repressor protein; antirepressor 3312365..3313003 Escherichia coli O104:H4 str. 2011C-3493 13701311 YP_006779932.1 CDS O3K_16290 NC_018658.1 3313059 3313490 D regulatory protein 3313059..3313490 Escherichia coli O104:H4 str. 2011C-3493 13701312 YP_006779933.1 CDS O3K_16295 NC_018658.1 3313487 3314113 D COG4725 Transcriptional activator, adenine-specific DNA methyltransferase; adenine methylase 3313487..3314113 Escherichia coli O104:H4 str. 2011C-3493 13701313 YP_006779934.1 CDS O3K_16300 NC_018658.1 3314073 3314285 D hypothetical protein 3314073..3314285 Escherichia coli O104:H4 str. 2011C-3493 13701314 YP_006779935.1 CDS O3K_16305 NC_018658.1 3314321 3314674 D hypothetical protein 3314321..3314674 Escherichia coli O104:H4 str. 2011C-3493 13701315 YP_006779936.1 CDS O3K_16310 NC_018658.1 3315039 3315290 D hypothetical protein 3315039..3315290 Escherichia coli O104:H4 str. 2011C-3493 13701316 YP_006779937.1 CDS O3K_16315 NC_018658.1 3315321 3315620 D putative excisionase 3315321..3315620 Escherichia coli O104:H4 str. 2011C-3493 13701317 YP_006779938.1 CDS O3K_16320 NC_018658.1 3315673 3316983 D COG0582 Integrase; integrase 3315673..3316983 Escherichia coli O104:H4 str. 2011C-3493 13701318 YP_006779939.1 CDS O3K_16325 NC_018658.1 3317013 3317558 D COG0655 Multimeric flavodoxin WrbA; NAD(P)H:quinone oxidoreductase 3317013..3317558 Escherichia coli O104:H4 str. 2011C-3493 13701319 YP_006779940.1 CDS O3K_16330 NC_018658.1 3317579 3317806 D hypothetical protein 3317579..3317806 Escherichia coli O104:H4 str. 2011C-3493 13701320 YP_006779941.1 CDS O3K_16335 NC_018658.1 3317844 3319085 R glucose-1-phosphatase/inositol phosphatase complement(3317844..3319085) Escherichia coli O104:H4 str. 2011C-3493 13701321 YP_006779942.1 CDS O3K_16340 NC_018658.1 3319374 3320561 R hypothetical protein complement(3319374..3320561) Escherichia coli O104:H4 str. 2011C-3493 13701322 YP_006779943.1 CDS O3K_16345 NC_018658.1 3320894 3321814 D COG2214 DnaJ-class molecular chaperone; curved DNA-binding protein CbpA 3320894..3321814 Escherichia coli O104:H4 str. 2011C-3493 13701323 YP_006779944.1 CDS O3K_16350 NC_018658.1 3321814 3322119 D chaperone-modulator protein CbpM 3321814..3322119 Escherichia coli O104:H4 str. 2011C-3493 13701324 YP_006779945.1 CDS torD NC_018658.1 3322212 3322811 R COG3381 Uncharacterized component of anaerobic dehydrogenases; chaperone protein TorD complement(3322212..3322811) Escherichia coli O104:H4 str. 2011C-3493 13701325 YP_006779946.1 CDS O3K_16360 NC_018658.1 3322808 3325354 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; trimethylamine N-oxide reductase I catalytic subunit complement(3322808..3325354) Escherichia coli O104:H4 str. 2011C-3493 13701326 YP_006779947.1 CDS O3K_16365 NC_018658.1 3325354 3326526 R COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; trimethylamine N-oxide reductase cytochrome c-type subunit complement(3325354..3326526) Escherichia coli O104:H4 str. 2011C-3493 13701327 YP_006779948.1 CDS O3K_16370 NC_018658.1 3326656 3327348 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator TorR 3326656..3327348 Escherichia coli O104:H4 str. 2011C-3493 13701328 YP_006779949.1 CDS O3K_16375 NC_018658.1 3327321 3328349 R COG1879 ABC-type sugar transport system, periplasmic component; TMAO reductase system periplasmic protein TorT complement(3327321..3328349) Escherichia coli O104:H4 str. 2011C-3493 13701329 YP_006779950.1 CDS O3K_16380 NC_018658.1 3328432 3331176 D COG0642 Signal transduction histidine kinase; hybrid sensory histidine kinase TorS 3328432..3331176 Escherichia coli O104:H4 str. 2011C-3493 13701330 YP_006779951.1 CDS O3K_16385 NC_018658.1 3331248 3332321 D COG0348 Polyferredoxin; 4Fe-4S binding protein 3331248..3332321 Escherichia coli O104:H4 str. 2011C-3493 13701331 YP_006779952.1 CDS O3K_16390 NC_018658.1 3332370 3332543 R putative regulator of phosphatidylethanolamine synthesis complement(3332370..3332543) Escherichia coli O104:H4 str. 2011C-3493 13701332 YP_006779953.1 CDS O3K_16395 NC_018658.1 3332533 3332763 R putative protein sfa; cold shock protein complement(3332533..3332763) Escherichia coli O104:H4 str. 2011C-3493 13701333 YP_006779954.1 CDS O3K_16400 NC_018658.1 3332937 3333149 R COG1278 Cold shock proteins; cold shock protein CspG complement(3332937..3333149) Escherichia coli O104:H4 str. 2011C-3493 13701334 YP_006779955.1 CDS O3K_16405 NC_018658.1 3333435 3333647 D COG1278 Cold shock proteins; cold shock-like protein CspH 3333435..3333647 Escherichia coli O104:H4 str. 2011C-3493 13701335 YP_006779956.1 CDS O3K_16410 NC_018658.1 3334501 3335145 D outer membrane lipoprotein 3334501..3335145 Escherichia coli O104:H4 str. 2011C-3493 13701336 YP_006779957.1 CDS O3K_16415 NC_018658.1 3335142 3335888 D hypothetical protein 3335142..3335888 Escherichia coli O104:H4 str. 2011C-3493 13701337 YP_006779958.1 CDS O3K_16420 NC_018658.1 3335888 3337984 D hypothetical protein 3335888..3337984 Escherichia coli O104:H4 str. 2011C-3493 13701338 YP_006779959.1 CDS O3K_16425 NC_018658.1 3338030 3339169 D COG1596 Periplasmic protein involved in polysaccharide export; polysaccharide export protein Wza 3338030..3339169 Escherichia coli O104:H4 str. 2011C-3493 13701339 YP_006779960.1 CDS etp NC_018658.1 3339157 3339603 D COG0394 Protein-tyrosine-phosphatase; phosphotyrosine-protein phosphatase 3339157..3339603 Escherichia coli O104:H4 str. 2011C-3493 13701340 YP_006779961.1 CDS O3K_16435 NC_018658.1 3339623 3341803 D COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; cryptic autophosphorylating protein tyrosine kinase Etk 3339623..3341803 Escherichia coli O104:H4 str. 2011C-3493 13701341 YP_006779962.1 CDS O3K_16440 NC_018658.1 3341918 3343216 R phosphoanhydride phosphorylase complement(3341918..3343216) Escherichia coli O104:H4 str. 2011C-3493 13701342 YP_006779963.1 CDS O3K_16445 NC_018658.1 3343296 3343388 R hypothetical protein complement(3343296..3343388) Escherichia coli O104:H4 str. 2011C-3493 13701343 YP_006779964.1 CDS O3K_16450 NC_018658.1 3343401 3344537 R COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome bd-II oxidase subunit 2 complement(3343401..3344537) Escherichia coli O104:H4 str. 2011C-3493 13701344 YP_006779965.1 CDS O3K_16455 NC_018658.1 3344549 3346093 R COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome bd-II oxidase subunit 1 complement(3344549..3346093) Escherichia coli O104:H4 str. 2011C-3493 13701345 YP_006779966.1 CDS O3K_16460 NC_018658.1 3346227 3347084 R hydrogenase-1 operon protein HyaF complement(3346227..3347084) Escherichia coli O104:H4 str. 2011C-3493 13701346 YP_006779967.1 CDS O3K_16465 NC_018658.1 3347081 3347479 R COG0526 Thiol-disulfide isomerase and thioredoxins; hydrogenase-1 operon protein HyaE complement(3347081..3347479) Escherichia coli O104:H4 str. 2011C-3493 13701347 YP_006779968.1 CDS O3K_16470 NC_018658.1 3347476 3348063 R COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 1 maturation protease complement(3347476..3348063) Escherichia coli O104:H4 str. 2011C-3493 13701348 YP_006779969.1 CDS O3K_16475 NC_018658.1 3348060 3348767 R COG1969 Ni,Fe-hydrogenase I cytochrome b subunit; hydrogenase 1 b-type cytochrome subunit complement(3348060..3348767) Escherichia coli O104:H4 str. 2011C-3493 13701349 YP_006779970.1 CDS O3K_16480 NC_018658.1 3348786 3350579 R COG0374 Ni,Fe-hydrogenase I large subunit; hydrogenase 1 large subunit complement(3348786..3350579) Escherichia coli O104:H4 str. 2011C-3493 13701350 YP_006779971.1 CDS O3K_16485 NC_018658.1 3350576 3351694 R COG1740 Ni,Fe-hydrogenase I small subunit; hydrogenase 1, small subunit complement(3350576..3351694) Escherichia coli O104:H4 str. 2011C-3493 13701351 YP_006779972.1 CDS O3K_16490 NC_018658.1 3352415 3353074 D COG0670 Integral membrane protein, interacts with FtsH; HflBKC-binding inner membrane protein 3352415..3353074 Escherichia coli O104:H4 str. 2011C-3493 13701353 YP_006779973.1 CDS O3K_16495 NC_018658.1 3353165 3353494 D COG2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit; sulfur transfer protein TusE 3353165..3353494 Escherichia coli O104:H4 str. 2011C-3493 13701354 YP_006779974.1 CDS O3K_16500 NC_018658.1 3353491 3353769 R COG1254 Acylphosphatases; acylphosphatase complement(3353491..3353769) Escherichia coli O104:H4 str. 2011C-3493 13701355 YP_006779975.1 CDS O3K_16505 NC_018658.1 3353864 3355054 D COG1092 Predicted SAM-dependent methyltransferases; 23S rRNA m(5)C1962 methyltransferase 3353864..3355054 Escherichia coli O104:H4 str. 2011C-3493 13701356 YP_006779976.1 CDS O3K_16510 NC_018658.1 3355112 3355429 D COG3785 Uncharacterized conserved protein; heat shock protein HspQ 3355112..3355429 Escherichia coli O104:H4 str. 2011C-3493 13701357 YP_006779977.1 CDS O3K_16515 NC_018658.1 3355474 3355887 R COG1832 Predicted CoA-binding protein; hypothetical protein complement(3355474..3355887) Escherichia coli O104:H4 str. 2011C-3493 13701358 YP_006779978.1 CDS O3K_16520 NC_018658.1 3356060 3356722 D COG3110 Uncharacterized protein conserved in bacteria; hypothetical protein 3356060..3356722 Escherichia coli O104:H4 str. 2011C-3493 13701359 YP_006779979.1 CDS mgsA NC_018658.1 3356818 3357276 D COG1803 Methylglyoxal synthase; methylglyoxal synthase 3356818..3357276 Escherichia coli O104:H4 str. 2011C-3493 13701360 YP_006779980.1 CDS helD NC_018658.1 3357308 3359362 R COG0210 Superfamily I DNA and RNA helicases; DNA helicase IV complement(3357308..3359362) Escherichia coli O104:H4 str. 2011C-3493 13701361 YP_006779981.1 CDS O3K_16535 NC_018658.1 3359485 3359931 D COG3304 Predicted membrane protein; hypothetical protein 3359485..3359931 Escherichia coli O104:H4 str. 2011C-3493 13701362 YP_006779982.1 CDS O3K_16540 NC_018658.1 3359941 3362103 D COG1289 Predicted membrane protein; hypothetical protein 3359941..3362103 Escherichia coli O104:H4 str. 2011C-3493 13701363 YP_006779983.1 CDS O3K_16545 NC_018658.1 3362066 3362695 R COG3070 Regulator of competence-specific genes; hypothetical protein complement(3362066..3362695) Escherichia coli O104:H4 str. 2011C-3493 13701364 YP_006779984.1 CDS O3K_16550 NC_018658.1 3362914 3363423 D COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation; SOS cell division inhibitor 3362914..3363423 Escherichia coli O104:H4 str. 2011C-3493 13701365 YP_006779985.1 CDS O3K_16555 NC_018658.1 3363780 3364820 D COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; outer membrane protein A 3363780..3364820 Escherichia coli O104:H4 str. 2011C-3493 13701366 YP_006779986.1 CDS O3K_16560 NC_018658.1 3364896 3365348 R COG3120 Uncharacterized protein conserved in bacteria; Ter macrodomain organizer matS-binding protein complement(3364896..3365348) Escherichia coli O104:H4 str. 2011C-3493 13701367 YP_006779987.1 CDS O3K_16565 NC_018658.1 3365534 3367294 D COG1067 Predicted ATP-dependent protease; peptidase, S16 (Lon protease) family protein 3365534..3367294 Escherichia coli O104:H4 str. 2011C-3493 13701368 YP_006779988.1 CDS O3K_16570 NC_018658.1 3367363 3367881 D COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; 3-hydroxydecanoyl-ACP dehydratase 3367363..3367881 Escherichia coli O104:H4 str. 2011C-3493 13701369 YP_006779989.1 CDS O3K_16575 NC_018658.1 3367951 3368118 R COG3130 Ribosome modulation factor; ribosome modulation factor complement(3367951..3368118) Escherichia coli O104:H4 str. 2011C-3493 13701370 YP_006779990.1 CDS O3K_16580 NC_018658.1 3368374 3368937 R COG3009 Uncharacterized protein conserved in bacteria; lipoprotein complement(3368374..3368937) Escherichia coli O104:H4 str. 2011C-3493 13701371 YP_006779991.1 CDS O3K_16585 NC_018658.1 3368934 3370574 R COG3008 Paraquat-inducible protein B; paraquat-inducible protein B complement(3368934..3370574) Escherichia coli O104:H4 str. 2011C-3493 13701372 YP_006779992.1 CDS O3K_16590 NC_018658.1 3370579 3371832 R COG2995 Uncharacterized paraquat-inducible protein A; paraquat-inducible membrane protein A complement(3370579..3371832) Escherichia coli O104:H4 str. 2011C-3493 13701373 YP_006779993.1 CDS O3K_16595 NC_018658.1 3371962 3373869 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase complement(3371962..3373869) Escherichia coli O104:H4 str. 2011C-3493 13701374 YP_006779994.1 CDS rlmL NC_018658.1 3373880 3375988 R COG0116 Predicted N6-adenine-specific DNA methylase; 23S rRNA m(2)G2445 methyltransferase complement(3373880..3375988) Escherichia coli O104:H4 str. 2011C-3493 13701375 YP_006779995.1 CDS O3K_16605 NC_018658.1 3376232 3377341 D COG3217 Uncharacterized Fe-S protein; 2Fe-2S cluster-containing protein 3376232..3377341 Escherichia coli O104:H4 str. 2011C-3493 13701376 YP_006779996.1 CDS O3K_16610 NC_018658.1 3377338 3377880 R hypothetical protein complement(3377338..3377880) Escherichia coli O104:H4 str. 2011C-3493 13701377 YP_006779997.1 CDS O3K_16615 NC_018658.1 3378054 3379064 R COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 2 complement(3378054..3379064) Escherichia coli O104:H4 str. 2011C-3493 13701378 YP_006779998.1 CDS O3K_16620 NC_018658.1 3379175 3379885 R COG3121 P pilus assembly protein, chaperone PapD; pili assembly chaperone complement(3379175..3379885) Escherichia coli O104:H4 str. 2011C-3493 13701379 YP_006779999.1 CDS O3K_16625 NC_018658.1 3379878 3380393 R COG3539 P pilus assembly protein, pilin FimA; putative fimbrial protein complement(3379878..3380393) Escherichia coli O104:H4 str. 2011C-3493 13701380 YP_006780000.1 CDS O3K_16630 NC_018658.1 3380401 3380943 R COG3539 P pilus assembly protein, pilin FimA; putative fimbrial-like adhesin protein complement(3380401..3380943) Escherichia coli O104:H4 str. 2011C-3493 13701381 YP_006780001.1 CDS O3K_16635 NC_018658.1 3380955 3382025 R putative fimbrial-like adhesin protein complement(3380955..3382025) Escherichia coli O104:H4 str. 2011C-3493 13701382 YP_006780002.1 CDS O3K_16640 NC_018658.1 3382016 3384616 R COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein complement(3382016..3384616) Escherichia coli O104:H4 str. 2011C-3493 13701383 YP_006780003.1 CDS O3K_16645 NC_018658.1 3384641 3385342 R COG3121 P pilus assembly protein, chaperone PapD; putative periplasmic pilin chaperone complement(3384641..3385342) Escherichia coli O104:H4 str. 2011C-3493 13701384 YP_006780004.1 CDS O3K_16650 NC_018658.1 3385425 3385967 R COG3539 P pilus assembly protein, pilin FimA; putative fimbrial-like adhesin protein complement(3385425..3385967) Escherichia coli O104:H4 str. 2011C-3493 13701385 YP_006780005.1 CDS O3K_16655 NC_018658.1 3386323 3386898 D COG0431 Predicted flavoprotein; NAD(P)H-dependent FMN reductase 3386323..3386898 Escherichia coli O104:H4 str. 2011C-3493 13701386 YP_006780006.1 CDS O3K_16660 NC_018658.1 3386891 3387850 D COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; alkanesulfonate transporter substrate-binding subunit 3386891..3387850 Escherichia coli O104:H4 str. 2011C-3493 13701387 YP_006780007.1 CDS O3K_16665 NC_018658.1 3387847 3388992 D COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkanesulfonate monooxygenase 3387847..3388992 Escherichia coli O104:H4 str. 2011C-3493 13701388 YP_006780008.1 CDS ssuC NC_018658.1 3389003 3389794 D COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; alkanesulfonate transporter permease 3389003..3389794 Escherichia coli O104:H4 str. 2011C-3493 13701389 YP_006780009.1 CDS ssuB NC_018658.1 3389791 3390558 D COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; aliphatic sulfonates transport ATP-binding subunit 3389791..3390558 Escherichia coli O104:H4 str. 2011C-3493 13701390 YP_006780010.1 CDS pepN NC_018658.1 3390765 3393377 R COG0308 Aminopeptidase N; aminopeptidase N complement(3390765..3393377) Escherichia coli O104:H4 str. 2011C-3493 13701391 YP_006780011.1 CDS O3K_16685 NC_018658.1 3393643 3394845 D COG1488 Nicotinic acid phosphoribosyltransferase; nicotinate phosphoribosyltransferase 3393643..3394845 Escherichia coli O104:H4 str. 2011C-3493 13701392 YP_006780012.1 CDS asnC NC_018658.1 3395014 3396414 D COG0017 Aspartyl/asparaginyl-tRNA synthetases; asparaginyl-tRNA synthetase 3395014..3396414 Escherichia coli O104:H4 str. 2011C-3493 13701393 YP_006780013.1 CDS O3K_16695 NC_018658.1 3397016 3398104 D COG3203 Outer membrane protein (porin); outer membrane protein F 3397016..3398104 Escherichia coli O104:H4 str. 2011C-3493 13701394 YP_006780014.1 CDS O3K_16700 NC_018658.1 3398120 3398290 R hypothetical protein complement(3398120..3398290) Escherichia coli O104:H4 str. 2011C-3493 13701395 YP_006780015.1 CDS O3K_16705 NC_018658.1 3398289 3399479 D COG1448 Aspartate/tyrosine/aromatic aminotransferase; aromatic amino acid aminotransferase 3398289..3399479 Escherichia coli O104:H4 str. 2011C-3493 13701396 YP_006780016.1 CDS O3K_16710 NC_018658.1 3399758 3400738 D COG3547 Transposase and inactivated derivatives; IS621 transposase 3399758..3400738 Escherichia coli O104:H4 str. 2011C-3493 13701397 YP_006780017.1 CDS O3K_16715 NC_018658.1 3400980 3401627 R COG0491 Zn-dependent hydrolases, including glyoxylases; putative metal-binding enzyme complement(3400980..3401627) Escherichia coli O104:H4 str. 2011C-3493 13701398 YP_006780018.1 CDS O3K_16720 NC_018658.1 3401654 3402202 R COG3108 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3401654..3402202) Escherichia coli O104:H4 str. 2011C-3493 13701399 YP_006780019.1 CDS O3K_16725 NC_018658.1 3402383 3404230 R COG2989 Uncharacterized protein conserved in bacteria; murein L,D-transpeptidase complement(3402383..3404230) Escherichia coli O104:H4 str. 2011C-3493 13701400 YP_006780020.1 CDS mukB NC_018658.1 3404491 3408951 R COG3096 Uncharacterized protein involved in chromosome partitioning; cell division protein MukB complement(3404491..3408951) Escherichia coli O104:H4 str. 2011C-3493 13701401 YP_006780021.1 CDS O3K_16735 NC_018658.1 3408951 3409655 R COG3095 Uncharacterized protein involved in chromosome partitioning; condesin subunit E complement(3408951..3409655) Escherichia coli O104:H4 str. 2011C-3493 13701402 YP_006780022.1 CDS O3K_16740 NC_018658.1 3409636 3410958 R COG3006 Uncharacterized protein involved in chromosome partitioning; condesin subunit F complement(3409636..3410958) Escherichia coli O104:H4 str. 2011C-3493 13701403 YP_006780023.1 CDS O3K_16745 NC_018658.1 3410955 3411740 R COG0500 SAM-dependent methyltransferases; putative S-adenosyl-L-methionine-dependent methyltransferase complement(3410955..3411740) Escherichia coli O104:H4 str. 2011C-3493 13701404 YP_006780024.1 CDS O3K_16750 NC_018658.1 3411876 3412655 D COG1434 Uncharacterized conserved protein; hypothetical protein 3411876..3412655 Escherichia coli O104:H4 str. 2011C-3493 13701405 YP_006780025.1 CDS O3K_16755 NC_018658.1 3412632 3413525 R hypothetical protein complement(3412632..3413525) Escherichia coli O104:H4 str. 2011C-3493 13701406 YP_006780026.1 CDS O3K_16760 NC_018658.1 3413679 3414425 R COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; 3-deoxy-manno-octulosonate cytidylyltransferase complement(3413679..3414425) Escherichia coli O104:H4 str. 2011C-3493 13701407 YP_006780027.1 CDS O3K_16765 NC_018658.1 3414422 3414604 R COG2835 Uncharacterized conserved protein; hypothetical protein complement(3414422..3414604) Escherichia coli O104:H4 str. 2011C-3493 13701408 YP_006780028.1 CDS O3K_16770 NC_018658.1 3414656 3415888 R COG3214 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3414656..3415888) Escherichia coli O104:H4 str. 2011C-3493 13701409 YP_006780029.1 CDS lpxK NC_018658.1 3415925 3416911 R COG1663 Tetraacyldisaccharide-1-P 4'-kinase; tetraacyldisaccharide 4'-kinase complement(3415925..3416911) Escherichia coli O104:H4 str. 2011C-3493 13701410 YP_006780030.1 CDS O3K_16780 NC_018658.1 3416908 3418656 R COG1132 ABC-type multidrug transport system, ATPase and permease components; lipid transporter ATP-binding/permease complement(3416908..3418656) Escherichia coli O104:H4 str. 2011C-3493 13701411 YP_006780031.1 CDS O3K_16785 NC_018658.1 3418693 3420957 R COG0658 Predicted membrane metal-binding protein; ComEC family competence protein complement(3418693..3420957) Escherichia coli O104:H4 str. 2011C-3493 13701412 YP_006780032.1 CDS ihfB NC_018658.1 3421164 3421448 R COG0776 Bacterial nucleoid DNA-binding protein; integration host factor subunit beta complement(3421164..3421448) Escherichia coli O104:H4 str. 2011C-3493 13701413 YP_006780033.1 CDS rpsA NC_018658.1 3421608 3423281 R COG0539 Ribosomal protein S1; 30S ribosomal protein S1 complement(3421608..3423281) Escherichia coli O104:H4 str. 2011C-3493 13701414 YP_006780034.1 CDS cmk NC_018658.1 3423392 3424075 R COG0283 Cytidylate kinase; cytidylate kinase complement(3423392..3424075) Escherichia coli O104:H4 str. 2011C-3493 13701415 YP_006780035.1 CDS O3K_16805 NC_018658.1 3424248 3425012 R COG0501 Zn-dependent protease with chaperone function; heat shock protein complement(3424248..3425012) Escherichia coli O104:H4 str. 2011C-3493 13701416 YP_006780036.1 CDS O3K_16810 NC_018658.1 3425181 3426464 R COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase complement(3425181..3426464) Escherichia coli O104:H4 str. 2011C-3493 13701417 YP_006780037.1 CDS O3K_16815 NC_018658.1 3426535 3427623 R COG1932 Phosphoserine aminotransferase; 3-phosphoserine/phosphohydroxythreonine aminotransferase complement(3426535..3427623) Escherichia coli O104:H4 str. 2011C-3493 13701418 YP_006780038.1 CDS O3K_16820 NC_018658.1 3427822 3428514 R COG2323 Predicted membrane protein; hypothetical protein complement(3427822..3428514) Escherichia coli O104:H4 str. 2011C-3493 13701419 YP_006780039.1 CDS O3K_16825 NC_018658.1 3428644 3430404 D COG1944 Uncharacterized conserved protein; hypothetical protein 3428644..3430404 Escherichia coli O104:H4 str. 2011C-3493 13701420 YP_006780040.1 CDS O3K_16830 NC_018658.1 3430809 3431666 D COG2116 Formate/nitrite family of transporters; formate transporter 3430809..3431666 Escherichia coli O104:H4 str. 2011C-3493 13701421 YP_006780041.1 CDS O3K_16835 NC_018658.1 3431721 3434003 D COG1882 Pyruvate-formate lyase; formate acetyltransferase 3431721..3434003 Escherichia coli O104:H4 str. 2011C-3493 13701422 YP_006780042.1 CDS pflA NC_018658.1 3434195 3434935 D COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase-activating enzyme 1 3434195..3434935 Escherichia coli O104:H4 str. 2011C-3493 13701423 YP_006780043.1 CDS O3K_16845 NC_018658.1 3435017 3435607 R COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); hypothetical protein complement(3435017..3435607) Escherichia coli O104:H4 str. 2011C-3493 13701424 YP_006780044.1 CDS O3K_16850 NC_018658.1 3435707 3436615 D COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator 3435707..3436615 Escherichia coli O104:H4 str. 2011C-3493 13701425 YP_006780045.1 CDS O3K_16855 NC_018658.1 3436616 3438046 R COG0531 Amino acid transporters; transporter complement(3436616..3438046) Escherichia coli O104:H4 str. 2011C-3493 13701426 YP_006780046.1 CDS O3K_16860 NC_018658.1 3438256 3439404 R COG0477 Permeases of the major facilitator superfamily; putative MFS family transporter protein complement(3438256..3439404) Escherichia coli O104:H4 str. 2011C-3493 13701427 YP_006780047.1 CDS O3K_16865 NC_018658.1 3439718 3440344 D COG1335 Amidases related to nicotinamidase; hydrolase 3439718..3440344 Escherichia coli O104:H4 str. 2011C-3493 13701428 YP_006780048.1 CDS O3K_16870 NC_018658.1 3440380 3441243 R COG3302 DMSO reductase anchor subunit; dimethyl sulfoxide reductase, anaerobic subunit C complement(3440380..3441243) Escherichia coli O104:H4 str. 2011C-3493 13701429 YP_006780049.1 CDS O3K_16875 NC_018658.1 3441245 3441862 R COG0437 Fe-S-cluster-containing hydrogenase components 1; anaerobic dimethyl sulfoxide reductase subunit B complement(3441245..3441862) Escherichia coli O104:H4 str. 2011C-3493 13701430 YP_006780050.1 CDS O3K_16880 NC_018658.1 3441873 3444317 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; anaerobic dimethyl sulfoxide reductase subunit A complement(3441873..3444317) Escherichia coli O104:H4 str. 2011C-3493 13701431 YP_006780051.1 CDS O3K_16885 NC_018658.1 3444556 3445848 R COG0172 Seryl-tRNA synthetase; seryl-tRNA synthetase complement(3444556..3445848) Escherichia coli O104:H4 str. 2011C-3493 13701432 YP_006780052.1 CDS O3K_16890 NC_018658.1 3445939 3447282 R COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA complement(3445939..3447282) Escherichia coli O104:H4 str. 2011C-3493 13701433 YP_006780053.1 CDS lolA NC_018658.1 3447293 3447904 R COG2834 Outer membrane lipoprotein-sorting protein; lipoprotein chaperone complement(3447293..3447904) Escherichia coli O104:H4 str. 2011C-3493 13701434 YP_006780054.1 CDS O3K_16900 NC_018658.1 3448059 3452126 R COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA translocase FtsK complement(3448059..3452126) Escherichia coli O104:H4 str. 2011C-3493 13701435 YP_006780055.1 CDS O3K_16905 NC_018658.1 3452261 3452755 R COG1522 Transcriptional regulators; leucine-responsive transcriptional regulator complement(3452261..3452755) Escherichia coli O104:H4 str. 2011C-3493 13701436 YP_006780056.1 CDS O3K_16910 NC_018658.1 3453300 3454265 D COG0492 Thioredoxin reductase; thioredoxin reductase 3453300..3454265 Escherichia coli O104:H4 str. 2011C-3493 13701437 YP_006780057.1 CDS O3K_16915 NC_018658.1 3454388 3456154 D COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; cysteine/glutathione ABC transporter membrane/ATP-binding protein 3454388..3456154 Escherichia coli O104:H4 str. 2011C-3493 13701438 YP_006780058.1 CDS O3K_16920 NC_018658.1 3456155 3457876 D COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components; cysteine/glutathione ABC transporter membrane/ATP-binding protein 3456155..3457876 Escherichia coli O104:H4 str. 2011C-3493 13701439 YP_006780059.1 CDS aat NC_018658.1 3457918 3458622 D COG2360 Leu/Phe-tRNA-protein transferase; leucyl/phenylalanyl-tRNA--protein transferase 3457918..3458622 Escherichia coli O104:H4 str. 2011C-3493 13701440 YP_006780060.1 CDS infA NC_018658.1 3458907 3459125 D COG0361 Translation initiation factor 1 (IF-1); translation initiation factor IF-1 3458907..3459125 Escherichia coli O104:H4 str. 2011C-3493 13701441 YP_006780061.1 CDS clpA NC_018658.1 3459810 3462086 R COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit complement(3459810..3462086) Escherichia coli O104:H4 str. 2011C-3493 13701443 YP_006780062.1 CDS clpS NC_018658.1 3462117 3462437 R COG2127 Uncharacterized conserved protein; ATP-dependent Clp protease adaptor protein ClpS complement(3462117..3462437) Escherichia coli O104:H4 str. 2011C-3493 13701444 YP_006780063.1 CDS O3K_16945 NC_018658.1 3462760 3462984 D COG1278 Cold shock proteins; stationary phase/starvation inducible regulatory protein CspD 3462760..3462984 Escherichia coli O104:H4 str. 2011C-3493 13701445 YP_006780064.1 CDS O3K_16950 NC_018658.1 3463057 3465003 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; macrolide transporter ATP-binding /permease complement(3463057..3465003) Escherichia coli O104:H4 str. 2011C-3493 13701446 YP_006780065.1 CDS O3K_16955 NC_018658.1 3465000 3466115 R COG0845 Membrane-fusion protein; macrolide transporter subunit MacA complement(3465000..3466115) Escherichia coli O104:H4 str. 2011C-3493 13701447 YP_006780066.1 CDS O3K_16960 NC_018658.1 3466230 3467222 D COG2990 Uncharacterized protein conserved in bacteria; hypothetical protein 3466230..3467222 Escherichia coli O104:H4 str. 2011C-3493 13701448 YP_006780067.1 CDS O3K_16965 NC_018658.1 3467219 3468877 R COG3593 Predicted ATP-dependent endonuclease of the OLD family; putative OLD family ATP-dependent endonuclease complement(3467219..3468877) Escherichia coli O104:H4 str. 2011C-3493 13701449 YP_006780068.1 CDS O3K_16970 NC_018658.1 3469303 3469998 D COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); aquaporin Z 3469303..3469998 Escherichia coli O104:H4 str. 2011C-3493 13701450 YP_006780069.1 CDS O3K_16975 NC_018658.1 3470493 3471392 D COG2431 Predicted membrane protein; transporter 3470493..3471392 Escherichia coli O104:H4 str. 2011C-3493 13701451 YP_006780070.1 CDS O3K_16980 NC_018658.1 3471536 3473188 D COG1151 6Fe-6S prismane cluster-containing protein; hybrid cluster protein 3471536..3473188 Escherichia coli O104:H4 str. 2011C-3493 13701452 YP_006780071.1 CDS O3K_16985 NC_018658.1 3473200 3474168 D COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; HCP oxidoreductase 3473200..3474168 Escherichia coli O104:H4 str. 2011C-3493 13701453 YP_006780072.1 CDS O3K_16990 NC_018658.1 3474301 3476019 D COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; pyruvate dehydrogenase 3474301..3476019 Escherichia coli O104:H4 str. 2011C-3493 13701454 YP_006780073.1 CDS O3K_16995 NC_018658.1 3476056 3477057 D COG2008 Threonine aldolase; L-threonine aldolase 3476056..3477057 Escherichia coli O104:H4 str. 2011C-3493 13701455 YP_006780074.1 CDS O3K_17000 NC_018658.1 3477068 3478498 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 3477068..3478498 Escherichia coli O104:H4 str. 2011C-3493 13701456 YP_006780075.1 CDS O3K_17005 NC_018658.1 3478597 3479610 D COG0451 Nucleoside-diphosphate-sugar epimerases; NAD dependent epimerase/dehydratase family protein 3478597..3479610 Escherichia coli O104:H4 str. 2011C-3493 13701457 YP_006780076.1 CDS O3K_17010 NC_018658.1 3479607 3480437 R COG3023 Negative regulator of beta-lactamase expression; N-acetylmuramoyl-L-alanine amidase AmiD complement(3479607..3480437) Escherichia coli O104:H4 str. 2011C-3493 13701458 YP_006780077.1 CDS O3K_17015 NC_018658.1 3480434 3480757 R COG0393 Uncharacterized conserved protein; hypothetical protein complement(3480434..3480757) Escherichia coli O104:H4 str. 2011C-3493 13701459 YP_006780078.1 CDS O3K_17020 NC_018658.1 3480883 3481398 D COG0174 Glutamine synthetase; lipoprotein 3480883..3481398 Escherichia coli O104:H4 str. 2011C-3493 13701460 YP_006780079.1 CDS artP NC_018658.1 3481616 3482344 D COG4161 ABC-type arginine transport system, ATPase component; arginine transporter ATP-binding subunit 3481616..3482344 Escherichia coli O104:H4 str. 2011C-3493 13701461 YP_006780080.1 CDS O3K_17030 NC_018658.1 3482362 3483093 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; arginine ABC transporter substrate-binding protein 3482362..3483093 Escherichia coli O104:H4 str. 2011C-3493 13701462 YP_006780081.1 CDS O3K_17035 NC_018658.1 3483100 3483816 D COG4215 ABC-type arginine transport system, permease component; arginine transporter permease subunit ArtQ 3483100..3483816 Escherichia coli O104:H4 str. 2011C-3493 13701463 YP_006780082.1 CDS artM NC_018658.1 3483816 3484484 D COG4160 ABC-type arginine/histidine transport system, permease component; arginine transporter permease subunit ArtM 3483816..3484484 Escherichia coli O104:H4 str. 2011C-3493 13701464 YP_006780083.1 CDS O3K_17045 NC_018658.1 3484776 3485507 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; arginine 3rd transport system periplasmic binding protein ArtJ 3484776..3485507 Escherichia coli O104:H4 str. 2011C-3493 13701465 YP_006780084.1 CDS rumB NC_018658.1 3485682 3486809 R COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; 23S rRNA methyluridine methyltransferase complement(3485682..3486809) Escherichia coli O104:H4 str. 2011C-3493 13701466 YP_006780085.1 CDS O3K_17055 NC_018658.1 3486850 3487338 R inner membrane protein complement(3486850..3487338) Escherichia coli O104:H4 str. 2011C-3493 13701467 YP_006780086.1 CDS O3K_17060 NC_018658.1 3487398 3488243 R COG1177 ABC-type spermidine/putrescine transport system, permease component II; putrescine ABC transporter permease complement(3487398..3488243) Escherichia coli O104:H4 str. 2011C-3493 13701468 YP_006780087.1 CDS O3K_17065 NC_018658.1 3488240 3489193 R COG1176 ABC-type spermidine/putrescine transport system, permease component I; putrescine ABC transporter permease complement(3488240..3489193) Escherichia coli O104:H4 str. 2011C-3493 13701469 YP_006780088.1 CDS potG NC_018658.1 3489203 3490336 R COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; putrescine ABC transporter ATP-binding protein complement(3489203..3490336) Escherichia coli O104:H4 str. 2011C-3493 13701470 YP_006780089.1 CDS O3K_17075 NC_018658.1 3490431 3491543 R COG0687 Spermidine/putrescine-binding periplasmic protein; putrescine ABC transporter substrate-binding protein complement(3490431..3491543) Escherichia coli O104:H4 str. 2011C-3493 13701471 YP_006780090.1 CDS O3K_17080 NC_018658.1 3491895 3492371 R sensory transduction regulator complement(3491895..3492371) Escherichia coli O104:H4 str. 2011C-3493 13701472 YP_006780091.1 CDS O3K_17085 NC_018658.1 3492459 3493361 R COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); ribosomal protein S6 modification protein complement(3492459..3493361) Escherichia coli O104:H4 str. 2011C-3493 13701473 YP_006780092.1 CDS O3K_17090 NC_018658.1 3493422 3494144 R COG0778 Nitroreductase; nitroreductase A complement(3493422..3494144) Escherichia coli O104:H4 str. 2011C-3493 13701474 YP_006780093.1 CDS O3K_17095 NC_018658.1 3494128 3494415 R hypothetical protein complement(3494128..3494415) Escherichia coli O104:H4 str. 2011C-3493 13701475 YP_006780094.1 CDS grxA NC_018658.1 3494575 3494832 D COG0695 Glutaredoxin and related proteins; glutaredoxin 3494575..3494832 Escherichia coli O104:H4 str. 2011C-3493 13701476 YP_006780095.1 CDS O3K_17105 NC_018658.1 3494862 3495239 R hypothetical protein complement(3494862..3495239) Escherichia coli O104:H4 str. 2011C-3493 13701477 YP_006780096.1 CDS O3K_17110 NC_018658.1 3495509 3497194 D COG2985 Predicted permease; transporter 3495509..3497194 Escherichia coli O104:H4 str. 2011C-3493 13701478 YP_006780097.1 CDS O3K_17115 NC_018658.1 3497369 3497905 R COG3226 Uncharacterized protein conserved in bacteria; DNA-binding transcriptional regulator complement(3497369..3497905) Escherichia coli O104:H4 str. 2011C-3493 13701479 YP_006780098.1 CDS O3K_17120 NC_018658.1 3497989 3499197 D COG0477 Permeases of the major facilitator superfamily; transporter 3497989..3499197 Escherichia coli O104:H4 str. 2011C-3493 13701480 YP_006780099.1 CDS O3K_17125 NC_018658.1 3499197 3500012 D COG0561 Predicted hydrolases of the HAD superfamily; phosphatase 3499197..3500012 Escherichia coli O104:H4 str. 2011C-3493 13701481 YP_006780100.1 CDS O3K_17130 NC_018658.1 3500098 3500382 D hypothetical protein 3500098..3500382 Escherichia coli O104:H4 str. 2011C-3493 13701482 YP_006780101.1 CDS O3K_17135 NC_018658.1 3500423 3501655 R COG0477 Permeases of the major facilitator superfamily; multidrug efflux system translocase MdfA complement(3500423..3501655) Escherichia coli O104:H4 str. 2011C-3493 13701483 YP_006780102.1 CDS O3K_17140 NC_018658.1 3501940 3502536 D COG0671 Membrane-associated phospholipid phosphatase; undecaprenyl pyrophosphate phosphatase 3501940..3502536 Escherichia coli O104:H4 str. 2011C-3493 13701565 YP_006780103.1 CDS O3K_17145 NC_018658.1 3502594 3503352 D COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor DeoR 3502594..3503352 Escherichia coli O104:H4 str. 2011C-3493 13701566 YP_006780104.1 CDS O3K_17150 NC_018658.1 3503399 3504601 R COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase complement(3503399..3504601) Escherichia coli O104:H4 str. 2011C-3493 13701567 YP_006780105.1 CDS O3K_17155 NC_018658.1 3504848 3505474 D COG0625 Glutathione S-transferase; transferase 3504848..3505474 Escherichia coli O104:H4 str. 2011C-3493 13701568 YP_006780106.1 CDS O3K_17160 NC_018658.1 3505471 3506586 R COG2133 Glucose/sorbosone dehydrogenases; dehydrogenase complement(3505471..3506586) Escherichia coli O104:H4 str. 2011C-3493 13701569 YP_006780107.1 CDS bssR NC_018658.1 3506697 3507080 R biofilm formation regulatory protein BssR complement(3506697..3507080) Escherichia coli O104:H4 str. 2011C-3493 13701570 YP_006780108.1 CDS rimO NC_018658.1 3507293 3508618 D COG0621 2-methylthioadenine synthetase; 30S ribosomal protein S12 methylthiotransferase 3507293..3508618 Escherichia coli O104:H4 str. 2011C-3493 13701571 YP_006780109.1 CDS O3K_17175 NC_018658.1 3508665 3509993 R COG2199 FOG: GGDEF domain; putative diguanylate cyclase complement(3508665..3509993) Escherichia coli O104:H4 str. 2011C-3493 13701572 YP_006780110.1 CDS O3K_17180 NC_018658.1 3510001 3512349 R COG2200 FOG: EAL domain; hypothetical protein complement(3510001..3512349) Escherichia coli O104:H4 str. 2011C-3493 13701573 YP_006780111.1 CDS O3K_17185 NC_018658.1 3512527 3513438 R COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; glutathione ABC transporter permease GsiD complement(3512527..3513438) Escherichia coli O104:H4 str. 2011C-3493 13701574 YP_006780112.1 CDS O3K_17190 NC_018658.1 3513441 3514361 R COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; glutathione ABC transporter permease GsiC complement(3513441..3514361) Escherichia coli O104:H4 str. 2011C-3493 13701575 YP_006780113.1 CDS O3K_17195 NC_018658.1 3514379 3515917 R COG0747 ABC-type dipeptide transport system, periplasmic component; glutathione ABC transporter substrate-binding protein GsiB complement(3514379..3515917) Escherichia coli O104:H4 str. 2011C-3493 13701576 YP_006780114.1 CDS O3K_17200 NC_018658.1 3515937 3517808 R COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; glutathione transporter ATP-binding protein complement(3515937..3517808) Escherichia coli O104:H4 str. 2011C-3493 13701577 YP_006780115.1 CDS O3K_17205 NC_018658.1 3517795 3518760 R COG1446 Asparaginase; isoaspartyl peptidase complement(3517795..3518760) Escherichia coli O104:H4 str. 2011C-3493 13701578 YP_006780116.1 CDS O3K_17210 NC_018658.1 3518964 3520199 D COG0303 Molybdopterin biosynthesis enzyme; molybdopterin biosynthesis protein MoeA 3518964..3520199 Escherichia coli O104:H4 str. 2011C-3493 13701579 YP_006780117.1 CDS O3K_17215 NC_018658.1 3520199 3520948 D COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; molybdopterin biosynthesis protein MoeB 3520199..3520948 Escherichia coli O104:H4 str. 2011C-3493 13701580 YP_006780118.1 CDS O3K_17220 NC_018658.1 3521036 3521698 R COG0176 Transaldolase; fructose-6-phosphate aldolase complement(3521036..3521698) Escherichia coli O104:H4 str. 2011C-3493 13701581 YP_006780119.1 CDS O3K_17225 NC_018658.1 3521829 3522728 D COG1180 Pyruvate-formate lyase-activating enzyme; putative pyruvate formate-lyase 3 activating protein 3521829..3522728 Escherichia coli O104:H4 str. 2011C-3493 13701582 YP_006780120.1 CDS O3K_17230 NC_018658.1 3522734 3525166 D COG1882 Pyruvate-formate lyase; putative pyruvate formate lyase 3522734..3525166 Escherichia coli O104:H4 str. 2011C-3493 13701583 YP_006780121.1 CDS O3K_17235 NC_018658.1 3525312 3526127 D COG0561 Predicted hydrolases of the HAD superfamily; hydrolase 3525312..3526127 Escherichia coli O104:H4 str. 2011C-3493 13701584 YP_006780122.1 CDS O3K_17240 NC_018658.1 3526279 3527544 D hypothetical protein 3526279..3527544 Escherichia coli O104:H4 str. 2011C-3493 13701585 YP_006780123.1 CDS O3K_17245 NC_018658.1 3527800 3528780 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(3527800..3528780) Escherichia coli O104:H4 str. 2011C-3493 13701586 YP_006780124.1 CDS O3K_17250 NC_018658.1 3529059 3530651 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein complement(3529059..3530651) Escherichia coli O104:H4 str. 2011C-3493 13701587 YP_006780125.1 CDS O3K_17255 NC_018658.1 3530870 3531790 D COG1376 Uncharacterized protein conserved in bacteria; L,D-transpeptidase 3530870..3531790 Escherichia coli O104:H4 str. 2011C-3493 13701588 YP_006780126.1 CDS O3K_17260 NC_018658.1 3531849 3532967 R COG0471 Di- and tricarboxylate transporters; transporter complement(3531849..3532967) Escherichia coli O104:H4 str. 2011C-3493 13701589 YP_006780127.1 CDS O3K_17265 NC_018658.1 3532964 3533431 R COG1321 Mn-dependent transcriptional regulator; manganese transport regulator MntR complement(3532964..3533431) Escherichia coli O104:H4 str. 2011C-3493 13701590 YP_006780128.1 CDS O3K_17270 NC_018658.1 3533617 3533745 D hypothetical protein 3533617..3533745 Escherichia coli O104:H4 str. 2011C-3493 13701591 YP_006780129.1 CDS O3K_17275 NC_018658.1 3534017 3535600 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; hydrolase, inner membrane 3534017..3535600 Escherichia coli O104:H4 str. 2011C-3493 13701592 YP_006780130.1 CDS ompX NC_018658.1 3535649 3536164 R COG3637 Opacity protein and related surface antigens; outer membrane protein X complement(3535649..3536164) Escherichia coli O104:H4 str. 2011C-3493 13701593 YP_006780131.1 CDS O3K_17285 NC_018658.1 3536517 3537404 D COG5006 Predicted permease, DMT superfamily; threonine and homoserine efflux system 3536517..3537404 Escherichia coli O104:H4 str. 2011C-3493 13701594 YP_006780132.1 CDS O3K_17290 NC_018658.1 3537703 3538206 D COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); DNA starvation/stationary phase protection protein Dps 3537703..3538206 Escherichia coli O104:H4 str. 2011C-3493 13701595 YP_006780133.1 CDS glnH NC_018658.1 3538610 3539356 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamine ABC transporter substrate-binding protein 3538610..3539356 Escherichia coli O104:H4 str. 2011C-3493 13701596 YP_006780134.1 CDS glnP NC_018658.1 3539495 3540154 D COG0765 ABC-type amino acid transport system, permease component; glutamine ABC transporter permease 3539495..3540154 Escherichia coli O104:H4 str. 2011C-3493 13701597 YP_006780135.1 CDS glnQ NC_018658.1 3540151 3540873 D COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein 3540151..3540873 Escherichia coli O104:H4 str. 2011C-3493 13701598 YP_006780136.1 CDS O3K_17310 NC_018658.1 3540990 3543215 D COG0668 Small-conductance mechanosensitive channel; putative mechanosensitive channel protein 3540990..3543215 Escherichia coli O104:H4 str. 2011C-3493 13701599 YP_006780137.1 CDS O3K_17315 NC_018658.1 3543212 3544138 R COG3129 Predicted SAM-dependent methyltransferase; 23S rRNA mA1618 methyltransferase complement(3543212..3544138) Escherichia coli O104:H4 str. 2011C-3493 13701600 YP_006780138.1 CDS O3K_17320 NC_018658.1 3544270 3544674 D hypothetical protein 3544270..3544674 Escherichia coli O104:H4 str. 2011C-3493 13701601 YP_006780139.1 CDS O3K_17325 NC_018658.1 3544939 3547221 D COG4774 Outer membrane receptor for monomeric catechols; catecholate siderophore receptor Fiu 3544939..3547221 Escherichia coli O104:H4 str. 2011C-3493 13701602 YP_006780140.1 CDS O3K_17330 NC_018658.1 3547263 3547940 D COG3128 Uncharacterized iron-regulated protein; Fe(II)-dependent oxygenase superfamily protein 3547263..3547940 Escherichia coli O104:H4 str. 2011C-3493 13701603 YP_006780141.1 CDS O3K_17335 NC_018658.1 3548014 3548280 D COG1734 DnaK suppressor protein; hypothetical protein 3548014..3548280 Escherichia coli O104:H4 str. 2011C-3493 13701604 YP_006780142.1 CDS O3K_17340 NC_018658.1 3548545 3548805 D hypothetical protein 3548545..3548805 Escherichia coli O104:H4 str. 2011C-3493 13701605 YP_006780143.1 CDS O3K_17345 NC_018658.1 3549034 3550119 R COG2055 Malate/L-lactate dehydrogenases; putative dehydrogenase complement(3549034..3550119) Escherichia coli O104:H4 str. 2011C-3493 13701606 YP_006780144.1 CDS O3K_17350 NC_018658.1 3550260 3551222 R COG0547 Anthranilate phosphoribosyltransferase; glycosyl transferase complement(3550260..3551222) Escherichia coli O104:H4 str. 2011C-3493 13701607 YP_006780145.1 CDS dinG NC_018658.1 3551250 3553400 R COG1199 Rad3-related DNA helicases; ATP-dependent DNA helicase DinG complement(3551250..3553400) Escherichia coli O104:H4 str. 2011C-3493 13701608 YP_006780146.1 CDS O3K_17360 NC_018658.1 3553520 3554002 D COG3236 Uncharacterized protein conserved in bacteria; hypothetical protein 3553520..3554002 Escherichia coli O104:H4 str. 2011C-3493 13701609 YP_006780147.1 CDS O3K_17365 NC_018658.1 3554234 3555598 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlE complement(3554234..3555598) Escherichia coli O104:H4 str. 2011C-3493 13701610 YP_006780148.1 CDS O3K_17370 NC_018658.1 3555827 3556498 D COG1309 Transcriptional regulator; putative DNA-binding transcriptional regulator 3555827..3556498 Escherichia coli O104:H4 str. 2011C-3493 13701611 YP_006780149.1 CDS O3K_17375 NC_018658.1 3556501 3557496 D COG0845 Membrane-fusion protein; putative efflux pump membrane fusion protein 3556501..3557496 Escherichia coli O104:H4 str. 2011C-3493 13701612 YP_006780150.1 CDS O3K_17380 NC_018658.1 3557489 3559225 D COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 3557489..3559225 Escherichia coli O104:H4 str. 2011C-3493 13701613 YP_006780151.1 CDS O3K_17385 NC_018658.1 3559218 3560351 D COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 3559218..3560351 Escherichia coli O104:H4 str. 2011C-3493 13701614 YP_006780152.1 CDS O3K_17390 NC_018658.1 3560362 3561468 D COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 3560362..3561468 Escherichia coli O104:H4 str. 2011C-3493 13701615 YP_006780153.1 CDS O3K_17395 NC_018658.1 3561430 3561840 R COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; hypothetical protein complement(3561430..3561840) Escherichia coli O104:H4 str. 2011C-3493 13701616 YP_006780154.1 CDS O3K_17400 NC_018658.1 3561973 3562734 D COG3568 Metal-dependent hydrolase; hypothetical protein 3561973..3562734 Escherichia coli O104:H4 str. 2011C-3493 13701617 YP_006780155.1 CDS O3K_17405 NC_018658.1 3562731 3563972 D COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; cardiolipin synthase 2 3562731..3563972 Escherichia coli O104:H4 str. 2011C-3493 13701618 YP_006780156.1 CDS O3K_17410 NC_018658.1 3563972 3564928 D COG0392 Predicted integral membrane protein; hypothetical protein 3563972..3564928 Escherichia coli O104:H4 str. 2011C-3493 13701619 YP_006780157.1 CDS O3K_17415 NC_018658.1 3564964 3565677 R COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein complement(3564964..3565677) Escherichia coli O104:H4 str. 2011C-3493 13701620 YP_006780158.1 CDS O3K_17420 NC_018658.1 3565747 3566451 R COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein complement(3565747..3566451) Escherichia coli O104:H4 str. 2011C-3493 13701621 YP_006780159.1 CDS O3K_17425 NC_018658.1 3566596 3567300 R COG0670 Integral membrane protein, interacts with FtsH; inner membrane protein complement(3566596..3567300) Escherichia coli O104:H4 str. 2011C-3493 13701622 YP_006780160.1 CDS moaE NC_018658.1 3567437 3567889 R COG0314 Molybdopterin converting factor, large subunit; molybdopterin guanine dinucleotide biosynthesis protein MoaE complement(3567437..3567889) Escherichia coli O104:H4 str. 2011C-3493 13701623 YP_006780161.1 CDS moaD NC_018658.1 3567891 3568136 R COG1977 Molybdopterin converting factor, small subunit; molybdopterin synthase small subunit complement(3567891..3568136) Escherichia coli O104:H4 str. 2011C-3493 13701624 YP_006780162.1 CDS moaC NC_018658.1 3568129 3568614 R COG0315 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein MoaC complement(3568129..3568614) Escherichia coli O104:H4 str. 2011C-3493 13701625 YP_006780163.1 CDS O3K_17445 NC_018658.1 3568617 3569129 R COG0521 Molybdopterin biosynthesis enzymes; molybdenum cofactor biosynthesis protein B complement(3568617..3569129) Escherichia coli O104:H4 str. 2011C-3493 13701626 YP_006780164.1 CDS moaA NC_018658.1 3569151 3570140 R COG2896 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein A complement(3569151..3570140) Escherichia coli O104:H4 str. 2011C-3493 13701627 YP_006780165.1 CDS O3K_17455 NC_018658.1 3570537 3571445 D structural protein; COG0391 Uncharacterized conserved protein; putative transferase with NAD(P)-binding Rossmann-fold domain 3570537..3571445 Escherichia coli O104:H4 str. 2011C-3493 13701628 YP_006780166.1 CDS O3K_17460 NC_018658.1 3571637 3573658 R COG0556 Helicase subunit of the DNA excision repair complex; excinuclease ABC subunit B complement(3571637..3573658) Escherichia coli O104:H4 str. 2011C-3493 13701629 YP_006780167.1 CDS bioD NC_018658.1 3574237 3574914 R COG0132 Dethiobiotin synthetase; dithiobiotin synthetase complement(3574237..3574914) Escherichia coli O104:H4 str. 2011C-3493 13701630 YP_006780168.1 CDS O3K_17470 NC_018658.1 3574907 3575662 R COG0500 SAM-dependent methyltransferases; biotin biosynthesis protein BioC complement(3574907..3575662) Escherichia coli O104:H4 str. 2011C-3493 13701631 YP_006780169.1 CDS O3K_17475 NC_018658.1 3575649 3576803 R COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase complement(3575649..3576803) Escherichia coli O104:H4 str. 2011C-3493 13701632 YP_006780170.1 CDS O3K_17480 NC_018658.1 3576800 3577840 R COG0502 Biotin synthase and related enzymes; biotin synthase complement(3576800..3577840) Escherichia coli O104:H4 str. 2011C-3493 13701633 YP_006780171.1 CDS O3K_17485 NC_018658.1 3577927 3579216 D COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 3577927..3579216 Escherichia coli O104:H4 str. 2011C-3493 13701634 YP_006780172.1 CDS O3K_17490 NC_018658.1 3579275 3579751 D COG1881 Phospholipid-binding protein; putative kinase inhibitor protein 3579275..3579751 Escherichia coli O104:H4 str. 2011C-3493 13701635 YP_006780173.1 CDS O3K_17495 NC_018658.1 3580497 3581828 D COG2199 FOG: GGDEF domain; hypothetical protein 3580497..3581828 Escherichia coli O104:H4 str. 2011C-3493 13701717 YP_006780174.1 CDS O3K_17500 NC_018658.1 3581902 3582486 R tail fiber chaperone, Qin prophage complement(3581902..3582486) Escherichia coli O104:H4 str. 2011C-3493 13701718 YP_006780175.1 CDS O3K_17505 NC_018658.1 3582486 3584195 R putative phage tail fiber protein complement(3582486..3584195) Escherichia coli O104:H4 str. 2011C-3493 13701719 YP_006780176.1 CDS O3K_17510 NC_018658.1 3584173 3585063 D hypothetical protein 3584173..3585063 Escherichia coli O104:H4 str. 2011C-3493 13701720 YP_006780177.1 CDS O3K_17515 NC_018658.1 3585451 3585624 D hypothetical protein 3585451..3585624 Escherichia coli O104:H4 str. 2011C-3493 13701721 YP_006780178.1 CDS O3K_17520 NC_018658.1 3585625 3586224 R Lom-like outer membrane protein of phage origin complement(3585625..3586224) Escherichia coli O104:H4 str. 2011C-3493 13701722 YP_006780179.1 CDS O3K_17525 NC_018658.1 3586295 3589792 R COG4733 Phage-related protein, tail component; Host specificity protein J of prophage complement(3586295..3589792) Escherichia coli O104:H4 str. 2011C-3493 13701723 YP_006780180.1 CDS O3K_17530 NC_018658.1 3589853 3590524 R COG4723 Phage-related protein, tail component; Tail assembly protein I complement(3589853..3590524) Escherichia coli O104:H4 str. 2011C-3493 13701724 YP_006780181.1 CDS O3K_17535 NC_018658.1 3590422 3591165 R COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; tail fiber component K of prophage complement(3590422..3591165) Escherichia coli O104:H4 str. 2011C-3493 13701725 YP_006780182.1 CDS O3K_17540 NC_018658.1 3591171 3591869 R COG4672 Phage-related protein; Minor tail protein L complement(3591171..3591869) Escherichia coli O104:H4 str. 2011C-3493 13701726 YP_006780183.1 CDS O3K_17545 NC_018658.1 3591869 3592198 R COG4718 Phage-related protein; minor tail protein complement(3591869..3592198) Escherichia coli O104:H4 str. 2011C-3493 13701727 YP_006780184.1 CDS O3K_17550 NC_018658.1 3592195 3594756 R Minor tail protein precursor H complement(3592195..3594756) Escherichia coli O104:H4 str. 2011C-3493 13701728 YP_006780185.1 CDS O3K_17555 NC_018658.1 3594749 3595183 R putative minor tail protein complement(3594749..3595183) Escherichia coli O104:H4 str. 2011C-3493 13701729 YP_006780186.1 CDS O3K_17560 NC_018658.1 3595165 3595587 R Minor tail protein G complement(3595165..3595587) Escherichia coli O104:H4 str. 2011C-3493 13701730 YP_006780187.1 CDS O3K_17565 NC_018658.1 3595603 3596343 R COG5492 Bacterial surface proteins containing Ig-like domains; Major tail protein V complement(3595603..3596343) Escherichia coli O104:H4 str. 2011C-3493 13701731 YP_006780188.1 CDS O3K_17570 NC_018658.1 3596351 3596746 R COG0477 Permeases of the major facilitator superfamily; Minor tail protein U complement(3596351..3596746) Escherichia coli O104:H4 str. 2011C-3493 13701732 YP_006780189.1 CDS O3K_17575 NC_018658.1 3596743 3597321 R Minor tail protein Z (GpZ) complement(3596743..3597321) Escherichia coli O104:H4 str. 2011C-3493 13701733 YP_006780190.1 CDS O3K_17580 NC_018658.1 3597333 3597686 R Tail attachment protein (Minor capsid protein FII) from bacteriophage origin complement(3597333..3597686) Escherichia coli O104:H4 str. 2011C-3493 13701734 YP_006780191.1 CDS O3K_17585 NC_018658.1 3597698 3598093 R putative phage DNA packaging protein complement(3597698..3598093) Escherichia coli O104:H4 str. 2011C-3493 13701735 YP_006780192.1 CDS O3K_17590 NC_018658.1 3598135 3599160 R Major head coat protein from bacteriophage origin complement(3598135..3599160) Escherichia coli O104:H4 str. 2011C-3493 13701736 YP_006780193.1 CDS O3K_17595 NC_018658.1 3599216 3599548 R Head decoration protein from bacteriophage origin complement(3599216..3599548) Escherichia coli O104:H4 str. 2011C-3493 13701737 YP_006780194.1 CDS O3K_17600 NC_018658.1 3599558 3600877 R COG0616 Periplasmic serine proteases (ClpP class); Minor capsid protein C from bacteriophage origin complement(3599558..3600877) Escherichia coli O104:H4 str. 2011C-3493 13701738 YP_006780195.1 CDS O3K_17605 NC_018658.1 3600858 3602459 R COG5511 Bacteriophage capsid protein; phage portal protein, lambda family complement(3600858..3602459) Escherichia coli O104:H4 str. 2011C-3493 13701739 YP_006780196.1 CDS O3K_17610 NC_018658.1 3602456 3602662 R Lambda prophage-derived head-to-tail joining protein W complement(3602456..3602662) Escherichia coli O104:H4 str. 2011C-3493 13701740 YP_006780197.1 CDS O3K_17615 NC_018658.1 3602659 3602877 R bacteriophage tail assembly protein complement(3602659..3602877) Escherichia coli O104:H4 str. 2011C-3493 13701741 YP_006780198.1 CDS O3K_17620 NC_018658.1 3602922 3604583 R COG5525 Bacteriophage tail assembly protein; Terminase large subunit from bacteriophage origin complement(3602922..3604583) Escherichia coli O104:H4 str. 2011C-3493 13701742 YP_006780199.1 CDS O3K_17625 NC_018658.1 3604558 3605103 R COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; terminase small subunit complement(3604558..3605103) Escherichia coli O104:H4 str. 2011C-3493 13701743 YP_006780200.1 CDS O3K_17630 NC_018658.1 3605492 3605725 D Qin prophage 3605492..3605725 Escherichia coli O104:H4 str. 2011C-3493 13701744 YP_006780201.1 CDS O3K_17635 NC_018658.1 3605782 3606192 D COG5562 Phage envelope protein; phage protein 3605782..3606192 Escherichia coli O104:H4 str. 2011C-3493 13701745 YP_006780202.1 CDS O3K_17640 NC_018658.1 3606542 3607063 R phage protein complement(3606542..3607063) Escherichia coli O104:H4 str. 2011C-3493 13701746 YP_006780203.1 CDS O3K_17645 NC_018658.1 3607268 3607705 R bacteriophage lysis protein complement(3607268..3607705) Escherichia coli O104:H4 str. 2011C-3493 13701747 YP_006780204.1 CDS O3K_17650 NC_018658.1 3607702 3608199 R COG3772 Phage-related lysozyme (muraminidase); lysozyme, DLP12 prophage complement(3607702..3608199) Escherichia coli O104:H4 str. 2011C-3493 13701748 YP_006780205.1 CDS O3K_17655 NC_018658.1 3608199 3608414 R phage lysis protein complement(3608199..3608414) Escherichia coli O104:H4 str. 2011C-3493 13701749 YP_006780206.1 CDS O3K_17660 NC_018658.1 3609003 3610085 D COG3203 Outer membrane protein (porin); outer membrane porin, DLP12 prophage 3609003..3610085 Escherichia coli O104:H4 str. 2011C-3493 13701750 YP_006780207.1 CDS O3K_17665 NC_018658.1 3610274 3610657 R antitermination protein Q complement(3610274..3610657) Escherichia coli O104:H4 str. 2011C-3493 13701751 YP_006780208.1 CDS O3K_17670 NC_018658.1 3610743 3610883 R hypothetical protein complement(3610743..3610883) Escherichia coli O104:H4 str. 2011C-3493 13701752 YP_006780209.1 CDS O3K_17675 NC_018658.1 3610880 3611107 R COG4570 Holliday junction resolvase; endodeoxyribonuclease RUS complement(3610880..3611107) Escherichia coli O104:H4 str. 2011C-3493 13701753 YP_006780210.1 CDS O3K_17680 NC_018658.1 3611238 3611528 R hypothetical protein complement(3611238..3611528) Escherichia coli O104:H4 str. 2011C-3493 13701754 YP_006780211.1 CDS O3K_17685 NC_018658.1 3611521 3611691 R prophage protein NinE complement(3611521..3611691) Escherichia coli O104:H4 str. 2011C-3493 13701755 YP_006780212.1 CDS O3K_17690 NC_018658.1 3611691 3612146 R hypothetical protein complement(3611691..3612146) Escherichia coli O104:H4 str. 2011C-3493 13701756 YP_006780213.1 CDS O3K_17695 NC_018658.1 3612341 3612847 R hypothetical protein complement(3612341..3612847) Escherichia coli O104:H4 str. 2011C-3493 13701757 YP_006780214.1 CDS O3K_17700 NC_018658.1 3613169 3613408 R antirepressor protein complement(3613169..3613408) Escherichia coli O104:H4 str. 2011C-3493 13701758 YP_006780215.1 CDS O3K_17705 NC_018658.1 3613520 3614314 R COG1961 Site-specific recombinases, DNA invertase Pin homologs; putative phage recombinase complement(3613520..3614314) Escherichia coli O104:H4 str. 2011C-3493 13701759 YP_006780216.1 CDS emrE NC_018658.1 3614271 3614513 R COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein complement(3614271..3614513) Escherichia coli O104:H4 str. 2011C-3493 13701760 YP_006780217.1 CDS O3K_17715 NC_018658.1 3614560 3614862 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Ren protein from phage origin complement(3614560..3614862) Escherichia coli O104:H4 str. 2011C-3493 13701761 YP_006780218.1 CDS O3K_17720 NC_018658.1 3614859 3615560 R replication protein P of bacteriophage complement(3614859..3615560) Escherichia coli O104:H4 str. 2011C-3493 13701762 YP_006780219.1 CDS O3K_17725 NC_018658.1 3615557 3616486 R Replication protein O frm phage origin complement(3615557..3616486) Escherichia coli O104:H4 str. 2011C-3493 13701763 YP_006780220.1 CDS O3K_17730 NC_018658.1 3616573 3617112 R Regulatory protein CII (modular protein) from bacteriophage origin, coiled-coil complement(3616573..3617112) Escherichia coli O104:H4 str. 2011C-3493 13701764 YP_006780221.1 CDS O3K_17735 NC_018658.1 3617182 3617412 R phage regulatory protein Cro complement(3617182..3617412) Escherichia coli O104:H4 str. 2011C-3493 13701765 YP_006780222.1 CDS O3K_17740 NC_018658.1 3617518 3618207 D COG2932 Predicted transcriptional regulator; phage repressor protein CI 3617518..3618207 Escherichia coli O104:H4 str. 2011C-3493 13701766 YP_006780223.1 CDS O3K_17745 NC_018658.1 3618805 3619011 D putative prophage Kil protein 3618805..3619011 Escherichia coli O104:H4 str. 2011C-3493 13701767 YP_006780224.1 CDS O3K_17750 NC_018658.1 3619087 3619383 D host-nuclease inhibitor protein Gam of bacteriophage 3619087..3619383 Escherichia coli O104:H4 str. 2011C-3493 13701768 YP_006780225.1 CDS O3K_17755 NC_018658.1 3619389 3620174 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Bet protein 3619389..3620174 Escherichia coli O104:H4 str. 2011C-3493 13701769 YP_006780226.1 CDS O3K_17760 NC_018658.1 3620171 3620851 D exonuclease from phage origin 3620171..3620851 Escherichia coli O104:H4 str. 2011C-3493 13701770 YP_006780227.1 CDS O3K_17765 NC_018658.1 3620842 3621030 D hypothetical protein 3620842..3621030 Escherichia coli O104:H4 str. 2011C-3493 13701771 YP_006780228.1 CDS O3K_17770 NC_018658.1 3621003 3621194 D phage protein 3621003..3621194 Escherichia coli O104:H4 str. 2011C-3493 13701772 YP_006780229.1 CDS O3K_17775 NC_018658.1 3621191 3621274 D hypothetical protein 3621191..3621274 Escherichia coli O104:H4 str. 2011C-3493 13701773 YP_006780230.1 CDS O3K_17780 NC_018658.1 3621205 3621486 D hypothetical protein 3621205..3621486 Escherichia coli O104:H4 str. 2011C-3493 13701774 YP_006780231.1 CDS O3K_17785 NC_018658.1 3621585 3621806 D COG1734 DnaK suppressor protein; hypothetical protein 3621585..3621806 Escherichia coli O104:H4 str. 2011C-3493 13701775 YP_006780232.1 CDS O3K_17790 NC_018658.1 3622017 3622547 R hypothetical protein complement(3622017..3622547) Escherichia coli O104:H4 str. 2011C-3493 13701776 YP_006780233.1 CDS O3K_17795 NC_018658.1 3622862 3623029 D hypothetical protein 3622862..3623029 Escherichia coli O104:H4 str. 2011C-3493 13701777 YP_006780234.1 CDS O3K_17800 NC_018658.1 3623069 3623287 D Excisionase 3623069..3623287 Escherichia coli O104:H4 str. 2011C-3493 13701778 YP_006780235.1 CDS O3K_17805 NC_018658.1 3623265 3624335 D COG0582 Integrase; Integrase from phage 3623265..3624335 Escherichia coli O104:H4 str. 2011C-3493 13701779 YP_006780236.1 CDS O3K_17810 NC_018658.1 3624470 3625753 D COG4677 Pectin methylesterase; acyl-CoA thioesterase 3624470..3625753 Escherichia coli O104:H4 str. 2011C-3493 13701780 YP_006780237.1 CDS O3K_17815 NC_018658.1 3625987 3628248 R COG1048 Aconitase A; putative hydratase complement(3625987..3628248) Escherichia coli O104:H4 str. 2011C-3493 13701781 YP_006780238.1 CDS O3K_17820 NC_018658.1 3628431 3629864 R COG0471 Di- and tricarboxylate transporters; transporter complement(3628431..3629864) Escherichia coli O104:H4 str. 2011C-3493 13701782 YP_006780239.1 CDS O3K_17825 NC_018658.1 3629940 3630992 R COG2828 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3629940..3630992) Escherichia coli O104:H4 str. 2011C-3493 13701783 YP_006780240.1 CDS O3K_17830 NC_018658.1 3631176 3632129 D COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator 3631176..3632129 Escherichia coli O104:H4 str. 2011C-3493 13701784 YP_006780241.1 CDS O3K_17835 NC_018658.1 3632170 3633165 R COG2706 3-carboxymuconate cyclase; 6-phosphogluconolactonase complement(3632170..3633165) Escherichia coli O104:H4 str. 2011C-3493 13701785 YP_006780242.1 CDS O3K_17840 NC_018658.1 3633320 3634138 D COG0561 Predicted hydrolases of the HAD superfamily; pyridoxal phosphate (PLP) phosphatase 3633320..3634138 Escherichia coli O104:H4 str. 2011C-3493 13701786 YP_006780243.1 CDS modC NC_018658.1 3634139 3635197 R COG4148 ABC-type molybdate transport system, ATPase component; molybdate transporter ATP-binding protein complement(3634139..3635197) Escherichia coli O104:H4 str. 2011C-3493 13701868 YP_006780244.1 CDS modB NC_018658.1 3635200 3635889 R COG4149 ABC-type molybdate transport system, permease component; molybdate ABC transporter permease complement(3635200..3635889) Escherichia coli O104:H4 str. 2011C-3493 13701869 YP_006780245.1 CDS modA NC_018658.1 3635889 3636662 R COG0725 ABC-type molybdate transport system, periplasmic component; molybdate transporter periplasmic protein complement(3635889..3636662) Escherichia coli O104:H4 str. 2011C-3493 13701870 YP_006780246.1 CDS O3K_17860 NC_018658.1 3636829 3636978 R hypothetical protein complement(3636829..3636978) Escherichia coli O104:H4 str. 2011C-3493 13701871 YP_006780247.1 CDS O3K_17865 NC_018658.1 3637107 3637895 D COG2005 N-terminal domain of molybdenum-binding protein; DNA-binding transcriptional regulator ModE 3637107..3637895 Escherichia coli O104:H4 str. 2011C-3493 13701872 YP_006780248.1 CDS O3K_17870 NC_018658.1 3637963 3639435 D COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; putative molybdenum transport ATP-binding protein ModF 3637963..3639435 Escherichia coli O104:H4 str. 2011C-3493 13701873 YP_006780249.1 CDS O3K_17875 NC_018658.1 3639696 3640712 D COG1087 UDP-glucose 4-epimerase; UDP-galactose-4-epimerase 3639696..3640712 Escherichia coli O104:H4 str. 2011C-3493 13701874 YP_006780250.1 CDS O3K_17880 NC_018658.1 3640722 3641768 D COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 3640722..3641768 Escherichia coli O104:H4 str. 2011C-3493 13701875 YP_006780251.1 CDS O3K_17885 NC_018658.1 3641772 3642920 D COG0153 Galactokinase; galactokinase 3641772..3642920 Escherichia coli O104:H4 str. 2011C-3493 13701876 YP_006780252.1 CDS galM NC_018658.1 3642914 3643954 D COG2017 Galactose mutarotase and related enzymes; galactose-1-epimerase 3642914..3643954 Escherichia coli O104:H4 str. 2011C-3493 13701877 YP_006780253.1 CDS gpmA NC_018658.1 3644159 3644911 D COG0588 Phosphoglycerate mutase 1; phosphoglyceromutase 3644159..3644911 Escherichia coli O104:H4 str. 2011C-3493 13701878 YP_006780254.1 CDS O3K_17900 NC_018658.1 3645069 3646121 R COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3645069..3646121) Escherichia coli O104:H4 str. 2011C-3493 13701879 YP_006780255.1 CDS O3K_17905 NC_018658.1 3646437 3646817 D hypothetical protein 3646437..3646817 Escherichia coli O104:H4 str. 2011C-3493 13701880 YP_006780256.1 CDS O3K_17910 NC_018658.1 3646931 3647872 D COG1230 Co/Zn/Cd efflux system component; zinc transporter ZitB 3646931..3647872 Escherichia coli O104:H4 str. 2011C-3493 13701881 YP_006780257.1 CDS O3K_17915 NC_018658.1 3647869 3648588 R COG3201 Nicotinamide mononucleotide transporter; nicotinamide riboside transporter PnuC complement(3647869..3648588) Escherichia coli O104:H4 str. 2011C-3493 13701882 YP_006780258.1 CDS O3K_17920 NC_018658.1 3648626 3649669 R COG0379 Quinolinate synthase; quinolinate synthetase complement(3648626..3649669) Escherichia coli O104:H4 str. 2011C-3493 13701883 YP_006780259.1 CDS O3K_17925 NC_018658.1 3651138 3651929 R COG1729 Uncharacterized protein conserved in bacteria; tol-pal system protein YbgF complement(3651138..3651929) Escherichia coli O104:H4 str. 2011C-3493 13701891 YP_006780260.1 CDS O3K_17930 NC_018658.1 3651939 3652460 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated outer membrane lipoprotein complement(3651939..3652460) Escherichia coli O104:H4 str. 2011C-3493 13701892 YP_006780261.1 CDS tolB NC_018658.1 3652495 3653787 R COG0823 Periplasmic component of the Tol biopolymer transport system; translocation protein TolB complement(3652495..3653787) Escherichia coli O104:H4 str. 2011C-3493 13701893 YP_006780262.1 CDS tolA NC_018658.1 3653920 3655185 R COG3064 Membrane protein involved in colicin uptake; cell envelope integrity inner membrane protein TolA complement(3653920..3655185) Escherichia coli O104:H4 str. 2011C-3493 13701894 YP_006780263.1 CDS O3K_17945 NC_018658.1 3655250 3655678 R COG0848 Biopolymer transport protein; colicin uptake protein TolR complement(3655250..3655678) Escherichia coli O104:H4 str. 2011C-3493 13701895 YP_006780264.1 CDS O3K_17950 NC_018658.1 3655682 3656374 R COG0811 Biopolymer transport proteins; colicin uptake protein TolQ complement(3655682..3656374) Escherichia coli O104:H4 str. 2011C-3493 13701896 YP_006780265.1 CDS O3K_17955 NC_018658.1 3656371 3656775 R COG0824 Predicted thioesterase; acyl-CoA thioesterase YbgC complement(3656371..3656775) Escherichia coli O104:H4 str. 2011C-3493 13701897 YP_006780266.1 CDS O3K_17960 NC_018658.1 3656925 3657218 R COG3790 Predicted membrane protein; hypothetical protein complement(3656925..3657218) Escherichia coli O104:H4 str. 2011C-3493 13701898 YP_006780267.1 CDS O3K_17965 NC_018658.1 3657218 3657331 R COG4890 Predicted outer membrane lipoprotein; cyd operon protein YbgT complement(3657218..3657331) Escherichia coli O104:H4 str. 2011C-3493 13701899 YP_006780268.1 CDS O3K_17970 NC_018658.1 3657346 3658485 R COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome d ubiquinol oxidase subunit 2 complement(3657346..3658485) Escherichia coli O104:H4 str. 2011C-3493 13701900 YP_006780269.1 CDS O3K_17975 NC_018658.1 3658501 3660069 R COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome d terminal oxidase subunit 1 complement(3658501..3660069) Escherichia coli O104:H4 str. 2011C-3493 13701901 YP_006780270.1 CDS O3K_17980 NC_018658.1 3660664 3660891 R hypothetical protein complement(3660664..3660891) Escherichia coli O104:H4 str. 2011C-3493 13701902 YP_006780271.1 CDS O3K_17985 NC_018658.1 3660916 3663549 R COG0383 Alpha-mannosidase; alpha-mannosidase complement(3660916..3663549) Escherichia coli O104:H4 str. 2011C-3493 13701903 YP_006780272.1 CDS O3K_17990 NC_018658.1 3663567 3665543 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC complement(3663567..3665543) Escherichia coli O104:H4 str. 2011C-3493 13701904 YP_006780273.1 CDS O3K_17995 NC_018658.1 3665652 3666374 D COG2188 Transcriptional regulators; DNA-binding transcriptional repressor MngR 3665652..3666374 Escherichia coli O104:H4 str. 2011C-3493 13701905 YP_006780274.1 CDS O3K_18000 NC_018658.1 3666478 3667347 R COG0074 Succinyl-CoA synthetase, alpha subunit; succinyl-CoA synthetase subunit alpha complement(3666478..3667347) Escherichia coli O104:H4 str. 2011C-3493 13701906 YP_006780275.1 CDS sucC NC_018658.1 3667347 3668513 R COG0045 Succinyl-CoA synthetase, beta subunit; succinyl-CoA synthetase subunit beta complement(3667347..3668513) Escherichia coli O104:H4 str. 2011C-3493 13701907 YP_006780276.1 CDS O3K_18010 NC_018658.1 3668607 3669824 R COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; dihydrolipoamide succinyltransferase complement(3668607..3669824) Escherichia coli O104:H4 str. 2011C-3493 13701908 YP_006780277.1 CDS sucA NC_018658.1 3669839 3672640 R COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; 2-oxoglutarate dehydrogenase E1 component complement(3669839..3672640) Escherichia coli O104:H4 str. 2011C-3493 13701909 YP_006780278.1 CDS sdhB NC_018658.1 3672841 3673557 R COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; succinate dehydrogenase iron-sulfur subunit complement(3672841..3673557) Escherichia coli O104:H4 str. 2011C-3493 13701910 YP_006780279.1 CDS sdhA NC_018658.1 3673573 3675339 R COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; succinate dehydrogenase flavoprotein subunit complement(3673573..3675339) Escherichia coli O104:H4 str. 2011C-3493 13701911 YP_006780280.1 CDS sdhD NC_018658.1 3675339 3675686 R COG2142 Succinate dehydrogenase, hydrophobic anchor subunit; succinate dehydrogenase cytochrome b556 small membrane subunit complement(3675339..3675686) Escherichia coli O104:H4 str. 2011C-3493 13701912 YP_006780281.1 CDS sdhC NC_018658.1 3675680 3676069 R COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; succinate dehydrogenase cytochrome b556 large membrane subunit complement(3675680..3676069) Escherichia coli O104:H4 str. 2011C-3493 13701913 YP_006780282.1 CDS O3K_18040 NC_018658.1 3676605 3676790 R hypothetical protein complement(3676605..3676790) Escherichia coli O104:H4 str. 2011C-3493 13701914 YP_006780283.1 CDS gltA NC_018658.1 3676778 3678061 D COG0372 Citrate synthase; type II citrate synthase 3676778..3678061 Escherichia coli O104:H4 str. 2011C-3493 13701915 YP_006780284.1 CDS O3K_18050 NC_018658.1 3678451 3679017 D COG3539 P pilus assembly protein, pilin FimA; putative fimbrial-like protein 3678451..3679017 Escherichia coli O104:H4 str. 2011C-3493 13701916 YP_006780285.1 CDS O3K_18055 NC_018658.1 3679077 3679325 D COG3188 P pilus assembly protein, porin PapC; fimbrial biogenesis outer membrane usher protein 3679077..3679325 Escherichia coli O104:H4 str. 2011C-3493 13701917 YP_006780286.1 CDS O3K_18060 NC_018658.1 3679354 3679629 D COG3677 Transposase and inactivated derivatives; InsA 3679354..3679629 Escherichia coli O104:H4 str. 2011C-3493 13701918 YP_006780287.1 CDS O3K_18065 NC_018658.1 3679548 3680051 D COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 3679548..3680051 Escherichia coli O104:H4 str. 2011C-3493 13701919 YP_006780288.1 CDS O3K_18070 NC_018658.1 3680086 3680736 D hypothetical protein 3680086..3680736 Escherichia coli O104:H4 str. 2011C-3493 13701920 YP_006780289.1 CDS O3K_18075 NC_018658.1 3680888 3681934 D COG3180 Putative ammonia monooxygenase; transport protein 3680888..3681934 Escherichia coli O104:H4 str. 2011C-3493 13701921 YP_006780290.1 CDS O3K_18080 NC_018658.1 3681931 3682722 R COG0266 Formamidopyrimidine-DNA glycosylase; endonuclease VIII complement(3681931..3682722) Escherichia coli O104:H4 str. 2011C-3493 13701922 YP_006780291.1 CDS O3K_18085 NC_018658.1 3682758 3683492 R COG1540 Uncharacterized proteins, homologs of lactam utilization protein B; LamB/YcsF family protein complement(3682758..3683492) Escherichia coli O104:H4 str. 2011C-3493 13701923 YP_006780292.1 CDS O3K_18090 NC_018658.1 3683482 3684414 R COG1984 Allophanate hydrolase subunit 2; hydrolase subunit complement(3683482..3684414) Escherichia coli O104:H4 str. 2011C-3493 13701924 YP_006780293.1 CDS O3K_18095 NC_018658.1 3684408 3685064 R COG2049 Allophanate hydrolase subunit 1; carboxylase complement(3684408..3685064) Escherichia coli O104:H4 str. 2011C-3493 13701925 YP_006780294.1 CDS O3K_18100 NC_018658.1 3685087 3685830 R COG0327 Uncharacterized conserved protein; metal-binding protein complement(3685087..3685830) Escherichia coli O104:H4 str. 2011C-3493 13701926 YP_006780295.1 CDS O3K_18105 NC_018658.1 3686101 3687582 D COG3104 Dipeptide/tripeptide permease; dipeptide/tripeptide permease D 3686101..3687582 Escherichia coli O104:H4 str. 2011C-3493 13701927 YP_006780296.1 CDS O3K_18110 NC_018658.1 3687624 3689042 R COG0415 Deoxyribodipyrimidine photolyase; deoxyribodipyrimidine photolyase complement(3687624..3689042) Escherichia coli O104:H4 str. 2011C-3493 13701928 YP_006780297.1 CDS O3K_18115 NC_018658.1 3689039 3689548 R COG3272 Uncharacterized conserved protein; hypothetical protein complement(3689039..3689548) Escherichia coli O104:H4 str. 2011C-3493 13701929 YP_006780298.1 CDS O3K_18120 NC_018658.1 3689696 3690364 R COG5433 Transposase; hypothetical protein complement(3689696..3690364) Escherichia coli O104:H4 str. 2011C-3493 13701930 YP_006780299.1 CDS O3K_18125 NC_018658.1 3690583 3690837 R COG5433 Transposase; transposase complement(3690583..3690837) Escherichia coli O104:H4 str. 2011C-3493 13701931 YP_006780300.1 CDS O3K_18130 NC_018658.1 3691063 3691632 R hypothetical protein complement(3691063..3691632) Escherichia coli O104:H4 str. 2011C-3493 13701932 YP_006780301.1 CDS O3K_18135 NC_018658.1 3691629 3693062 R COG3209 Rhs family protein; RhsC core protein complement(3691629..3693062) Escherichia coli O104:H4 str. 2011C-3493 13701933 YP_006780302.1 CDS O3K_18140 NC_018658.1 3693180 3693506 R hypothetical protein complement(3693180..3693506) Escherichia coli O104:H4 str. 2011C-3493 13701934 YP_006780303.1 CDS O3K_18145 NC_018658.1 3693506 3697699 R COG3209 Rhs family protein; rhsC element core protein RshC complement(3693506..3697699) Escherichia coli O104:H4 str. 2011C-3493 13701935 YP_006780304.1 CDS O3K_18150 NC_018658.1 3697942 3698148 R hypothetical protein complement(3697942..3698148) Escherichia coli O104:H4 str. 2011C-3493 13701936 YP_006780305.1 CDS O3K_18155 NC_018658.1 3698461 3698550 D potassium ion accessory transporter subunit 3698461..3698550 Escherichia coli O104:H4 str. 2011C-3493 13701937 YP_006780306.1 CDS O3K_18160 NC_018658.1 3698550 3700223 D COG2060 K+-transporting ATPase, A chain; potassium-transporting ATPase subunit A 3698550..3700223 Escherichia coli O104:H4 str. 2011C-3493 13702019 YP_006780307.1 CDS O3K_18165 NC_018658.1 3700246 3702294 D COG2216 High-affinity K+ transport system, ATPase chain B; potassium-transporting ATPase subunit B 3700246..3702294 Escherichia coli O104:H4 str. 2011C-3493 13702020 YP_006780308.1 CDS O3K_18170 NC_018658.1 3702303 3702875 D COG2156 K+-transporting ATPase, c chain; potassium-transporting ATPase subunit C 3702303..3702875 Escherichia coli O104:H4 str. 2011C-3493 13702021 YP_006780309.1 CDS O3K_18175 NC_018658.1 3702868 3705552 D COG2205 Osmosensitive K+ channel histidine kinase; sensor protein KdpD 3702868..3705552 Escherichia coli O104:H4 str. 2011C-3493 13702022 YP_006780310.1 CDS O3K_18180 NC_018658.1 3705549 3706226 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator KdpE 3705549..3706226 Escherichia coli O104:H4 str. 2011C-3493 13702023 YP_006780311.1 CDS O3K_18185 NC_018658.1 3706916 3709114 D COG1982 Arginine/lysine/ornithine decarboxylases; ornithine decarboxylase 3706916..3709114 Escherichia coli O104:H4 str. 2011C-3493 13702024 YP_006780312.1 CDS potE NC_018658.1 3709111 3710430 D COG0531 Amino acid transporters; putrescine transporter 3709111..3710430 Escherichia coli O104:H4 str. 2011C-3493 13702025 YP_006780313.1 CDS O3K_18195 NC_018658.1 3710486 3712126 R COG0033 Phosphoglucomutase; phosphoglucomutase complement(3710486..3712126) Escherichia coli O104:H4 str. 2011C-3493 13702026 YP_006780314.1 CDS O3K_18200 NC_018658.1 3712152 3712697 R COG3057 Negative regulator of replication initiationR; replication initiation regulator SeqA complement(3712152..3712697) Escherichia coli O104:H4 str. 2011C-3493 13702027 YP_006780315.1 CDS O3K_18205 NC_018658.1 3712882 3713646 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); acyl-CoA esterase 3712882..3713646 Escherichia coli O104:H4 str. 2011C-3493 13702028 YP_006780316.1 CDS O3K_18210 NC_018658.1 3713786 3714079 D LexA regulated protein 3713786..3714079 Escherichia coli O104:H4 str. 2011C-3493 13702029 YP_006780317.1 CDS O3K_18215 NC_018658.1 3714219 3714749 D COG0716 Flavodoxins; flavodoxin FldA 3714219..3714749 Escherichia coli O104:H4 str. 2011C-3493 13702030 YP_006780318.1 CDS O3K_18220 NC_018658.1 3714959 3715045 D ryhB-regulated fur leader peptide 3714959..3715045 Escherichia coli O104:H4 str. 2011C-3493 13702031 YP_006780319.1 CDS fur NC_018658.1 3715038 3715484 D COG0735 Fe2+/Zn2+ uptake regulation proteins; ferric uptake regulator 3715038..3715484 Escherichia coli O104:H4 str. 2011C-3493 13702032 YP_006780320.1 CDS O3K_18230 NC_018658.1 3715568 3715894 R COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein complement(3715568..3715894) Escherichia coli O104:H4 str. 2011C-3493 13702033 YP_006780321.1 CDS O3K_18235 NC_018658.1 3715944 3717350 R putative outer membrane porin complement(3715944..3717350) Escherichia coli O104:H4 str. 2011C-3493 13702034 YP_006780322.1 CDS O3K_18240 NC_018658.1 3717796 3719460 R COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutaminyl-tRNA synthetase complement(3717796..3719460) Escherichia coli O104:H4 str. 2011C-3493 13702035 YP_006780323.1 CDS O3K_18245 NC_018658.1 3719663 3721609 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system N-acetyl glucosamine specific transporter subunit IIABC complement(3719663..3721609) Escherichia coli O104:H4 str. 2011C-3493 13702036 YP_006780324.1 CDS nagB NC_018658.1 3721942 3722742 D COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; glucosamine-6-phosphate deaminase 3721942..3722742 Escherichia coli O104:H4 str. 2011C-3493 13702037 YP_006780325.1 CDS nagA NC_018658.1 3722802 3723950 D COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 3722802..3723950 Escherichia coli O104:H4 str. 2011C-3493 13702038 YP_006780326.1 CDS O3K_18260 NC_018658.1 3723959 3725179 D COG1940 Transcriptional regulator/sugar kinase; N-acetylglucosamine repressor 3723959..3725179 Escherichia coli O104:H4 str. 2011C-3493 13702039 YP_006780327.1 CDS O3K_18265 NC_018658.1 3725227 3725979 D COG0647 Predicted sugar phosphatases of the HAD superfamily; UMP phosphatase 3725227..3725979 Escherichia coli O104:H4 str. 2011C-3493 13702040 YP_006780328.1 CDS asnB NC_018658.1 3726236 3727900 D COG0367 Asparagine synthase (glutamine-hydrolyzing); asparagine synthetase B 3726236..3727900 Escherichia coli O104:H4 str. 2011C-3493 13702041 YP_006780329.1 CDS ubiF NC_018658.1 3729138 3730313 R COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase complement(3729138..3730313) Escherichia coli O104:H4 str. 2011C-3493 13702049 YP_006780330.1 CDS O3K_18280 NC_018658.1 3730459 3731883 D COG0621 2-methylthioadenine synthetase; (dimethylallyl)adenosine tRNA methylthiotransferase 3730459..3731883 Escherichia coli O104:H4 str. 2011C-3493 13702050 YP_006780331.1 CDS O3K_18285 NC_018658.1 3731997 3733076 D COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; PhoH family protein 3731997..3733076 Escherichia coli O104:H4 str. 2011C-3493 13702051 YP_006780332.1 CDS O3K_18290 NC_018658.1 3733073 3733540 D COG0319 Predicted metal-dependent hydrolase; metal-binding heat shock protein 3733073..3733540 Escherichia coli O104:H4 str. 2011C-3493 13702052 YP_006780333.1 CDS O3K_18295 NC_018658.1 3733630 3734508 D COG4535 Putative Mg2+ and Co2+ transporter CorC; magnesium/cobalt efflux protein CorC 3733630..3734508 Escherichia coli O104:H4 str. 2011C-3493 13702053 YP_006780334.1 CDS lnt NC_018658.1 3734533 3736071 D COG0815 Apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 3734533..3736071 Escherichia coli O104:H4 str. 2011C-3493 13702054 YP_006780335.1 CDS O3K_18315 NC_018658.1 3738480 3739388 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamate and aspartate transporter subunit 3738480..3739388 Escherichia coli O104:H4 str. 2011C-3493 13702055 YP_006780336.1 CDS O3K_18320 NC_018658.1 3739558 3740298 D COG0765 ABC-type amino acid transport system, permease component; glutamate/aspartate transport system permease GltJ 3739558..3740298 Escherichia coli O104:H4 str. 2011C-3493 13702056 YP_006780337.1 CDS O3K_18325 NC_018658.1 3740298 3740972 D COG0765 ABC-type amino acid transport system, permease component; glutamate/aspartate transport system permease GltK 3740298..3740972 Escherichia coli O104:H4 str. 2011C-3493 13702057 YP_006780338.1 CDS O3K_18330 NC_018658.1 3740972 3741697 D COG1126 ABC-type polar amino acid transport system, ATPase component; glutamate/aspartate transport ATP-binding protein gltL 3740972..3741697 Escherichia coli O104:H4 str. 2011C-3493 13702058 YP_006780339.1 CDS rihA NC_018658.1 3741815 3742750 D COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase 1 3741815..3742750 Escherichia coli O104:H4 str. 2011C-3493 13702059 YP_006780340.1 CDS O3K_18340 NC_018658.1 3742834 3744504 D COG0443 Molecular chaperone; molecular chaperone DnaK 3742834..3744504 Escherichia coli O104:H4 str. 2011C-3493 13702060 YP_006780341.1 CDS O3K_18345 NC_018658.1 3744564 3746015 R Hsc56 co-chaperone of HscC complement(3744564..3746015) Escherichia coli O104:H4 str. 2011C-3493 13702061 YP_006780342.1 CDS O3K_18350 NC_018658.1 3746012 3746719 R hypothetical protein complement(3746012..3746719) Escherichia coli O104:H4 str. 2011C-3493 13702062 YP_006780343.1 CDS O3K_18355 NC_018658.1 3746820 3747374 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 3746820..3747374 Escherichia coli O104:H4 str. 2011C-3493 13702063 YP_006780344.1 CDS O3K_18360 NC_018658.1 3747384 3748811 R COG2214 DnaJ-class molecular chaperone; DnaJ-class chaperone complement(3747384..3748811) Escherichia coli O104:H4 str. 2011C-3493 13702064 YP_006780345.1 CDS O3K_18365 NC_018658.1 3748808 3749515 R hypothetical protein complement(3748808..3749515) Escherichia coli O104:H4 str. 2011C-3493 13702065 YP_006780346.1 CDS O3K_18370 NC_018658.1 3749679 3750656 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 3749679..3750656 Escherichia coli O104:H4 str. 2011C-3493 13702066 YP_006780347.1 CDS O3K_18375 NC_018658.1 3750726 3751208 R COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein complement(3750726..3751208) Escherichia coli O104:H4 str. 2011C-3493 13702067 YP_006780348.1 CDS leuS NC_018658.1 3751443 3754025 D COG0495 Leucyl-tRNA synthetase; leucyl-tRNA synthetase 3751443..3754025 Escherichia coli O104:H4 str. 2011C-3493 13702068 YP_006780349.1 CDS O3K_18385 NC_018658.1 3754040 3754621 D COG2980 Rare lipoprotein B; LPS-assembly lipoprotein RlpB 3754040..3754621 Escherichia coli O104:H4 str. 2011C-3493 13702069 YP_006780350.1 CDS holA NC_018658.1 3754621 3755652 D COG1466 DNA polymerase III, delta subunit; DNA polymerase III subunit delta 3754621..3755652 Escherichia coli O104:H4 str. 2011C-3493 13702070 YP_006780351.1 CDS nadD NC_018658.1 3755654 3756295 D COG1057 Nicotinic acid mononucleotide adenylyltransferase; nicotinic acid mononucleotide adenylyltransferase 3755654..3756295 Escherichia coli O104:H4 str. 2011C-3493 13702071 YP_006780352.1 CDS O3K_18400 NC_018658.1 3756319 3756930 D COG0406 Fructose-2,6-bisphosphatase; alpha-ribazole phosphatase 3756319..3756930 Escherichia coli O104:H4 str. 2011C-3493 13702072 YP_006780353.1 CDS O3K_18405 NC_018658.1 3757190 3757507 D COG0799 Uncharacterized homolog of plant Iojap protein; ribosome-associated protein 3757190..3757507 Escherichia coli O104:H4 str. 2011C-3493 13702073 YP_006780354.1 CDS O3K_18410 NC_018658.1 3757511 3757978 D COG1576 Uncharacterized conserved protein; rRNA large subunit methyltransferase 3757511..3757978 Escherichia coli O104:H4 str. 2011C-3493 13702074 YP_006780355.1 CDS O3K_18415 NC_018658.1 3758009 3759910 D COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 2 3758009..3759910 Escherichia coli O104:H4 str. 2011C-3493 13702075 YP_006780356.1 CDS O3K_18420 NC_018658.1 3759913 3761025 D COG0772 Bacterial cell division membrane protein; cell wall shape-determining protein 3759913..3761025 Escherichia coli O104:H4 str. 2011C-3493 13702076 YP_006780357.1 CDS O3K_18425 NC_018658.1 3761036 3762124 D COG0797 Lipoproteins; rare lipoprotein A 3761036..3762124 Escherichia coli O104:H4 str. 2011C-3493 13702077 YP_006780358.1 CDS O3K_18430 NC_018658.1 3762263 3763474 D COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 3762263..3763474 Escherichia coli O104:H4 str. 2011C-3493 13702078 YP_006780359.1 CDS O3K_18435 NC_018658.1 3763585 3763848 D COG2921 Uncharacterized conserved protein; hypothetical protein 3763585..3763848 Escherichia coli O104:H4 str. 2011C-3493 13702079 YP_006780360.1 CDS O3K_18440 NC_018658.1 3763949 3764590 D COG0321 Lipoate-protein ligase B; lipoate-protein ligase B 3763949..3764590 Escherichia coli O104:H4 str. 2011C-3493 13702080 YP_006780361.1 CDS O3K_18445 NC_018658.1 3764642 3764791 R COG0474 Cation transport ATPase; hypothetical protein complement(3764642..3764791) Escherichia coli O104:H4 str. 2011C-3493 13702081 YP_006780362.1 CDS O3K_18450 NC_018658.1 3764849 3765802 D COG0583 Transcriptional regulator; putative DNA-binding transcriptional regulator 3764849..3765802 Escherichia coli O104:H4 str. 2011C-3493 13702082 YP_006780363.1 CDS O3K_18455 NC_018658.1 3766011 3766976 D COG0320 Lipoate synthase; lipoyl synthase 3766011..3766976 Escherichia coli O104:H4 str. 2011C-3493 13702083 YP_006780364.1 CDS tatE NC_018658.1 3767077 3767280 R COG1826 Sec-independent protein secretion pathway components; twin arginine translocase protein E complement(3767077..3767280) Escherichia coli O104:H4 str. 2011C-3493 13702084 YP_006780365.1 CDS O3K_18465 NC_018658.1 3767409 3768197 R COG0388 Predicted amidohydrolase; hypothetical protein complement(3767409..3768197) Escherichia coli O104:H4 str. 2011C-3493 13702085 YP_006780366.1 CDS O3K_18470 NC_018658.1 3768290 3768673 D COG0239 Integral membrane protein possibly involved in chromosome condensation; chromosome condensation membrane protein 3768290..3768673 Escherichia coli O104:H4 str. 2011C-3493 13702086 YP_006780367.1 CDS cspE NC_018658.1 3768727 3768936 R COG1278 Cold shock proteins; cold shock protein CspE complement(3768727..3768936) Escherichia coli O104:H4 str. 2011C-3493 13702087 YP_006780368.1 CDS pagP NC_018658.1 3769111 3769671 R phospholipid:lipid A palmitoyltransferase complement(3769111..3769671) Escherichia coli O104:H4 str. 2011C-3493 13702088 YP_006780369.1 CDS dcuC NC_018658.1 3770260 3771645 D COG3069 C4-dicarboxylate transporter; C4-dicarboxylate transporter DcuC 3770260..3771645 Escherichia coli O104:H4 str. 2011C-3493 13702089 YP_006780370.1 CDS dpiA NC_018658.1 3771686 3772366 R COG4565 Response regulator of citrate/malate metabolism; two-component response regulator DpiA complement(3771686..3772366) Escherichia coli O104:H4 str. 2011C-3493 13702169 YP_006780371.1 CDS dpiB NC_018658.1 3772335 3773993 R COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; sensor histidine kinase DpiB complement(3772335..3773993) Escherichia coli O104:H4 str. 2011C-3493 13702170 YP_006780372.1 CDS O3K_18500 NC_018658.1 3774373 3775431 D COG3053 Citrate lyase synthetase; citrate lyase synthetase 3774373..3775431 Escherichia coli O104:H4 str. 2011C-3493 13702171 YP_006780373.1 CDS O3K_18505 NC_018658.1 3775446 3775742 D COG3052 Citrate lyase, gamma subunit; citrate lyase subunit gamma 3775446..3775742 Escherichia coli O104:H4 str. 2011C-3493 13702172 YP_006780374.1 CDS O3K_18510 NC_018658.1 3775739 3776647 D COG2301 Citrate lyase beta subunit; citrate lyase subunit beta 3775739..3776647 Escherichia coli O104:H4 str. 2011C-3493 13702173 YP_006780375.1 CDS O3K_18515 NC_018658.1 3776658 3778190 D COG3051 Citrate lyase, alpha subunit; citrate lyase subunit alpha 3776658..3778190 Escherichia coli O104:H4 str. 2011C-3493 13702174 YP_006780376.1 CDS citX NC_018658.1 3778194 3778745 D COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase); 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 3778194..3778745 Escherichia coli O104:H4 str. 2011C-3493 13702175 YP_006780377.1 CDS citG NC_018658.1 3778720 3779598 D COG1767 Triphosphoribosyl-dephospho-CoA synthetase; triphosphoribosyl-dephospho-CoA synthase 3778720..3779598 Escherichia coli O104:H4 str. 2011C-3493 13702176 YP_006780378.1 CDS O3K_18530 NC_018658.1 3779649 3781112 D COG0471 Di- and tricarboxylate transporters; citrate/succinate antiporter CitT 3779649..3781112 Escherichia coli O104:H4 str. 2011C-3493 13702177 YP_006780379.1 CDS O3K_18535 NC_018658.1 3781226 3782032 D COG3719 Ribonuclease I; ribonuclease I 3781226..3782032 Escherichia coli O104:H4 str. 2011C-3493 13702178 YP_006780380.1 CDS O3K_18540 NC_018658.1 3782262 3782672 D COG0782 Transcription elongation factor; nucleoside diphosphate kinase regulator 3782262..3782672 Escherichia coli O104:H4 str. 2011C-3493 13702179 YP_006780381.1 CDS O3K_18545 NC_018658.1 3782903 3784141 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase zinc-binding dehydrogenase family protein complement(3782903..3784141) Escherichia coli O104:H4 str. 2011C-3493 13702180 YP_006780382.1 CDS O3K_18550 NC_018658.1 3784362 3784790 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspG 3784362..3784790 Escherichia coli O104:H4 str. 2011C-3493 13702181 YP_006780383.1 CDS O3K_18555 NC_018658.1 3784911 3786476 R COG3634 Alkyl hydroperoxide reductase, large subunit; alkyl hydroperoxide reductase subunit F complement(3784911..3786476) Escherichia coli O104:H4 str. 2011C-3493 13702182 YP_006780384.1 CDS O3K_18560 NC_018658.1 3786605 3787168 R COG0450 Peroxiredoxin; alkyl hydroperoxide reductase subunit C complement(3786605..3787168) Escherichia coli O104:H4 str. 2011C-3493 13702183 YP_006780385.1 CDS dsbG NC_018658.1 3787540 3788286 D COG1651 Protein-disulfide isomerase; disulfide isomerase/thiol-disulfide oxidase 3787540..3788286 Escherichia coli O104:H4 str. 2011C-3493 13702184 YP_006780386.1 CDS O3K_18570 NC_018658.1 3788495 3789397 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 3788495..3789397 Escherichia coli O104:H4 str. 2011C-3493 13702185 YP_006780387.1 CDS O3K_18575 NC_018658.1 3789544 3790764 D COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase; phosphoadenosine phosphosulfate reductase family protein 3789544..3790764 Escherichia coli O104:H4 str. 2011C-3493 13702186 YP_006780388.1 CDS O3K_18580 NC_018658.1 3790749 3791366 D COG1475 Predicted transcriptional regulators; Immunoglobulin-binding regulator family protein 3790749..3791366 Escherichia coli O104:H4 str. 2011C-3493 13702187 YP_006780389.1 CDS O3K_18585 NC_018658.1 3791367 3792527 R COG0436 Aspartate/tyrosine/aromatic aminotransferase; methionine aminotransferase complement(3791367..3792527) Escherichia coli O104:H4 str. 2011C-3493 13702188 YP_006780390.1 CDS O3K_18590 NC_018658.1 3792636 3793724 D COG0371 Glycerol dehydrogenase and related enzymes; oxidoreductase 3792636..3793724 Escherichia coli O104:H4 str. 2011C-3493 13702189 YP_006780391.1 CDS O3K_18595 NC_018658.1 3793734 3793931 R COG2879 Uncharacterized small protein; hypothetical protein complement(3793734..3793931) Escherichia coli O104:H4 str. 2011C-3493 13702190 YP_006780392.1 CDS O3K_18600 NC_018658.1 3794113 3796218 R COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein A complement(3794113..3796218) Escherichia coli O104:H4 str. 2011C-3493 13702191 YP_006780393.1 CDS O3K_18605 NC_018658.1 3796399 3796812 R COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; thioesterase complement(3796399..3796812) Escherichia coli O104:H4 str. 2011C-3493 13702192 YP_006780394.1 CDS O3K_18610 NC_018658.1 3796815 3797561 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2,3-dihydroxybenzoate-2,3-dehydrogenase complement(3796815..3797561) Escherichia coli O104:H4 str. 2011C-3493 13702193 YP_006780395.1 CDS O3K_18615 NC_018658.1 3797561 3798418 R COG1535 Isochorismate hydrolase; isochorismatase complement(3797561..3798418) Escherichia coli O104:H4 str. 2011C-3493 13702194 YP_006780396.1 CDS entE NC_018658.1 3798432 3800042 R COG1021 Peptide arylation enzymes; enterobactin synthase subunit E complement(3798432..3800042) Escherichia coli O104:H4 str. 2011C-3493 13702195 YP_006780397.1 CDS O3K_18625 NC_018658.1 3800052 3801227 R COG1169 Isochorismate synthase; isochorismate synthase EntC complement(3800052..3801227) Escherichia coli O104:H4 str. 2011C-3493 13702196 YP_006780398.1 CDS O3K_18630 NC_018658.1 3801602 3802558 D COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component; iron-enterobactin transporter periplasmic binding protein 3801602..3802558 Escherichia coli O104:H4 str. 2011C-3493 13702197 YP_006780399.1 CDS O3K_18635 NC_018658.1 3802562 3803812 R COG0477 Permeases of the major facilitator superfamily; enterobactin exporter EntS complement(3802562..3803812) Escherichia coli O104:H4 str. 2011C-3493 13702198 YP_006780400.1 CDS O3K_18640 NC_018658.1 3803923 3804927 D COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-enterobactin transporter membrane protein 3803923..3804927 Escherichia coli O104:H4 str. 2011C-3493 13702199 YP_006780401.1 CDS O3K_18645 NC_018658.1 3804924 3805916 D COG4779 ABC-type enterobactin transport system, permease component; iron-enterobactin transporter permease 3804924..3805916 Escherichia coli O104:H4 str. 2011C-3493 13702200 YP_006780402.1 CDS O3K_18650 NC_018658.1 3805913 3806728 D COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-enterobactin transporter ATP-binding protein 3805913..3806728 Escherichia coli O104:H4 str. 2011C-3493 13702201 YP_006780403.1 CDS O3K_18655 NC_018658.1 3806725 3807858 R COG3765 Chain length determinant protein; LPS O-antigen length regulator complement(3806725..3807858) Escherichia coli O104:H4 str. 2011C-3493 13702202 YP_006780404.1 CDS entF NC_018658.1 3808074 3811955 R COG1020 Non-ribosomal peptide synthetase modules and related proteins; enterobactin synthase subunit F complement(3808074..3811955) Escherichia coli O104:H4 str. 2011C-3493 13702203 YP_006780405.1 CDS O3K_18665 NC_018658.1 3811952 3812170 R COG3251 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3811952..3812170) Escherichia coli O104:H4 str. 2011C-3493 13702204 YP_006780406.1 CDS O3K_18670 NC_018658.1 3812173 3813297 R COG2382 Enterochelin esterase and related enzymes; enterobactin/ferric enterobactin esterase complement(3812173..3813297) Escherichia coli O104:H4 str. 2011C-3493 13702205 YP_006780407.1 CDS O3K_18675 NC_018658.1 3813618 3815858 D COG4771 Outer membrane receptor for ferrienterochelin and colicins; outer membrane receptor FepA 3813618..3815858 Escherichia coli O104:H4 str. 2011C-3493 13702206 YP_006780408.1 CDS O3K_18680 NC_018658.1 3816024 3816653 D COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 3816024..3816653 Escherichia coli O104:H4 str. 2011C-3493 13702207 YP_006780409.1 CDS O3K_18685 NC_018658.1 3816819 3818093 D COG3385 FOG: Transposase and inactivated derivatives; IS186, transposase 3816819..3818093 Escherichia coli O104:H4 str. 2011C-3493 13702208 YP_006780410.1 CDS O3K_18690 NC_018658.1 3818123 3818275 R regulatory peptide MokC complement(3818123..3818275) Escherichia coli O104:H4 str. 2011C-3493 13702209 YP_006780411.1 CDS O3K_18695 NC_018658.1 3818786 3819898 R COG3385 FOG: Transposase and inactivated derivatives; putative transposase insL for insertion sequence IS186 complement(3818786..3819898) Escherichia coli O104:H4 str. 2011C-3493 13702210 YP_006780412.1 CDS O3K_18700 NC_018658.1 3819975 3820127 R hypothetical protein complement(3819975..3820127) Escherichia coli O104:H4 str. 2011C-3493 13702211 YP_006780413.1 CDS O3K_18705 NC_018658.1 3820393 3820494 R hypothetical protein complement(3820393..3820494) Escherichia coli O104:H4 str. 2011C-3493 13702212 YP_006780414.1 CDS O3K_18710 NC_018658.1 3820569 3821687 D COG2170 Uncharacterized conserved protein; gamma-glutamyl:cysteine ligase 3820569..3821687 Escherichia coli O104:H4 str. 2011C-3493 13702213 YP_006780415.1 CDS O3K_18715 NC_018658.1 3821753 3822001 D inner membrane protein 3821753..3822001 Escherichia coli O104:H4 str. 2011C-3493 13702214 YP_006780416.1 CDS O3K_18720 NC_018658.1 3822066 3822434 D COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein 3822066..3822434 Escherichia coli O104:H4 str. 2011C-3493 13702215 YP_006780417.1 CDS O3K_18725 NC_018658.1 3822528 3823181 D COG0778 Nitroreductase; dihydropteridine reductase 3822528..3823181 Escherichia coli O104:H4 str. 2011C-3493 13702216 YP_006780418.1 CDS O3K_18730 NC_018658.1 3823289 3824536 D COG0668 Small-conductance mechanosensitive channel; putative mechanosensitive channel 3823289..3824536 Escherichia coli O104:H4 str. 2011C-3493 13702217 YP_006780419.1 CDS O3K_18735 NC_018658.1 3824604 3825980 R COG1113 Gamma-aminobutyrate permease and related permeases; phenylalanine transporter complement(3824604..3825980) Escherichia coli O104:H4 str. 2011C-3493 13702218 YP_006780420.1 CDS O3K_18740 NC_018658.1 3826082 3829225 R COG3696 Putative silver efflux pump; copper/silver efflux system, membrane component complement(3826082..3829225) Escherichia coli O104:H4 str. 2011C-3493 13702219 YP_006780421.1 CDS O3K_18745 NC_018658.1 3829237 3830460 R COG0845 Membrane-fusion protein; copper/silver efflux system membrane fusion protein CusB complement(3829237..3830460) Escherichia coli O104:H4 str. 2011C-3493 13702220 YP_006780422.1 CDS O3K_18750 NC_018658.1 3830476 3830808 R COG5569 Uncharacterized conserved protein; copper-binding protein complement(3830476..3830808) Escherichia coli O104:H4 str. 2011C-3493 13702221 YP_006780423.1 CDS O3K_18755 NC_018658.1 3830832 3832214 R COG1538 Outer membrane protein; copper/silver efflux system outer membrane protein CusC complement(3830832..3832214) Escherichia coli O104:H4 str. 2011C-3493 13702222 YP_006780424.1 CDS O3K_18760 NC_018658.1 3832371 3833054 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator CusR 3832371..3833054 Escherichia coli O104:H4 str. 2011C-3493 13702223 YP_006780425.1 CDS O3K_18765 NC_018658.1 3833044 3834492 D COG0642 Signal transduction histidine kinase; sensor kinase CusS 3833044..3834492 Escherichia coli O104:H4 str. 2011C-3493 13702224 YP_006780426.1 CDS O3K_18770 NC_018658.1 3835229 3837130 D COG3501 Uncharacterized protein conserved in bacteria; Rhs element Vgr protein 3835229..3837130 Escherichia coli O104:H4 str. 2011C-3493 13702225 YP_006780427.1 CDS O3K_18775 NC_018658.1 3837158 3837619 D COG5435 Uncharacterized conserved protein; hypothetical protein 3837158..3837619 Escherichia coli O104:H4 str. 2011C-3493 13702226 YP_006780428.1 CDS O3K_18780 NC_018658.1 3841167 3842501 D COG3209 Rhs family protein; Rhs core protein with extension 3841167..3842501 Escherichia coli O104:H4 str. 2011C-3493 13702227 YP_006780429.1 CDS O3K_18785 NC_018658.1 3842498 3842749 D hypothetical protein 3842498..3842749 Escherichia coli O104:H4 str. 2011C-3493 13702228 YP_006780430.1 CDS O3K_18790 NC_018658.1 3842864 3843175 D hypothetical protein 3842864..3843175 Escherichia coli O104:H4 str. 2011C-3493 13702229 YP_006780431.1 CDS O3K_18795 NC_018658.1 3843279 3844415 D COG5433 Transposase; transposase 3843279..3844415 Escherichia coli O104:H4 str. 2011C-3493 13702230 YP_006780432.1 CDS nfrB NC_018658.1 3844684 3846921 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; bacteriophage N4 adsorption protein B 3844684..3846921 Escherichia coli O104:H4 str. 2011C-3493 13702231 YP_006780433.1 CDS O3K_18805 NC_018658.1 3846908 3849880 D COG0457 FOG: TPR repeat; bacteriophage N4 receptor, outer membrane subunit 3846908..3849880 Escherichia coli O104:H4 str. 2011C-3493 13702232 YP_006780434.1 CDS O3K_18810 NC_018658.1 3849881 3850771 D hypothetical protein 3849881..3850771 Escherichia coli O104:H4 str. 2011C-3493 13702233 YP_006780435.1 CDS O3K_18815 NC_018658.1 3850954 3851715 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator EnvY 3850954..3851715 Escherichia coli O104:H4 str. 2011C-3493 13702234 YP_006780436.1 CDS O3K_18825 NC_018658.1 3852080 3852712 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator FimZ 3852080..3852712 Escherichia coli O104:H4 str. 2011C-3493 13702236 YP_006780437.1 CDS O3K_18830 NC_018658.1 3852715 3853230 R COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein SfmF complement(3852715..3853230) Escherichia coli O104:H4 str. 2011C-3493 13702237 YP_006780438.1 CDS fimH NC_018658.1 3853241 3854248 R fimbrial-like adhesin complement(3853241..3854248) Escherichia coli O104:H4 str. 2011C-3493 13702238 YP_006780439.1 CDS O3K_18840 NC_018658.1 3854261 3856870 R COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein FimD complement(3854261..3856870) Escherichia coli O104:H4 str. 2011C-3493 13702307 YP_006780440.1 CDS O3K_18845 NC_018658.1 3856901 3857593 R COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein FimC complement(3856901..3857593) Escherichia coli O104:H4 str. 2011C-3493 13702308 YP_006780441.1 CDS O3K_18850 NC_018658.1 3857813 3858355 R COG3539 P pilus assembly protein, pilin FimA; type-1 fimbrial protein subunit A complement(3857813..3858355) Escherichia coli O104:H4 str. 2011C-3493 13702309 YP_006780442.1 CDS O3K_18855 NC_018658.1 3858836 3859702 D COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3858836..3859702 Escherichia coli O104:H4 str. 2011C-3493 13702310 YP_006780443.1 CDS O3K_18860 NC_018658.1 3859704 3859916 D COG2501 Uncharacterized conserved protein; hypothetical protein 3859704..3859916 Escherichia coli O104:H4 str. 2011C-3493 13702311 YP_006780444.1 CDS O3K_18865 NC_018658.1 3860024 3860545 D COG1988 Predicted membrane-bound metal-dependent hydrolases; inner membrane protein YbcI 3860024..3860545 Escherichia coli O104:H4 str. 2011C-3493 13702312 YP_006780445.1 CDS cysS NC_018658.1 3860581 3861966 R COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase complement(3860581..3861966) Escherichia coli O104:H4 str. 2011C-3493 13702313 YP_006780446.1 CDS O3K_18875 NC_018658.1 3862140 3862634 D COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase B 3862140..3862634 Escherichia coli O104:H4 str. 2011C-3493 13702314 YP_006780447.1 CDS O3K_18880 NC_018658.1 3862637 3863359 D COG2908 Uncharacterized protein conserved in bacteria; UDP-2,3-diacylglucosamine hydrolase 3862637..3863359 Escherichia coli O104:H4 str. 2011C-3493 13702315 YP_006780448.1 CDS O3K_18885 NC_018658.1 3863477 3863986 D COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; phosphoribosylaminoimidazole carboxylase catalytic subunit 3863477..3863986 Escherichia coli O104:H4 str. 2011C-3493 13702316 YP_006780449.1 CDS O3K_18890 NC_018658.1 3863983 3865050 D COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); phosphoribosylaminoimidazole carboxylase ATPase subunit 3863983..3865050 Escherichia coli O104:H4 str. 2011C-3493 13702317 YP_006780450.1 CDS O3K_18895 NC_018658.1 3865245 3866138 R COG0549 Carbamate kinase; carbamate kinase complement(3865245..3866138) Escherichia coli O104:H4 str. 2011C-3493 13702318 YP_006780451.1 CDS O3K_18900 NC_018658.1 3866135 3866950 R hypothetical protein complement(3866135..3866950) Escherichia coli O104:H4 str. 2011C-3493 13702319 YP_006780452.1 CDS O3K_18905 NC_018658.1 3866961 3868220 R hypothetical protein complement(3866961..3868220) Escherichia coli O104:H4 str. 2011C-3493 13702320 YP_006780453.1 CDS O3K_18910 NC_018658.1 3868230 3869897 R COG0074 Succinyl-CoA synthetase, alpha subunit; membrane protein FdrA complement(3868230..3869897) Escherichia coli O104:H4 str. 2011C-3493 13702321 YP_006780454.1 CDS O3K_18915 NC_018658.1 3870214 3871263 D COG2055 Malate/L-lactate dehydrogenases; ureidoglycolate dehydrogenase 3870214..3871263 Escherichia coli O104:H4 str. 2011C-3493 13702322 YP_006780455.1 CDS O3K_18920 NC_018658.1 3871285 3872520 D COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; allantoate amidohydrolase 3871285..3872520 Escherichia coli O104:H4 str. 2011C-3493 13702323 YP_006780456.1 CDS O3K_18925 NC_018658.1 3872531 3873316 D COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization; hypothetical protein 3872531..3873316 Escherichia coli O104:H4 str. 2011C-3493 13702324 YP_006780457.1 CDS O3K_18930 NC_018658.1 3873445 3874590 R COG1929 Glycerate kinase; glycerate kinase complement(3873445..3874590) Escherichia coli O104:H4 str. 2011C-3493 13702325 YP_006780458.1 CDS O3K_18935 NC_018658.1 3874612 3875913 R COG2233 Xanthine/uracil permeases; putative uracil/xanthine transporter complement(3874612..3875913) Escherichia coli O104:H4 str. 2011C-3493 13702326 YP_006780459.1 CDS O3K_18940 NC_018658.1 3875970 3877331 R COG0044 Dihydroorotase and related cyclic amidohydrolases; allantoinase complement(3875970..3877331) Escherichia coli O104:H4 str. 2011C-3493 13702327 YP_006780460.1 CDS O3K_18945 NC_018658.1 3877391 3878845 R COG1953 Cytosine/uracil/thiamine/allantoin permeases; allantoin permease complement(3877391..3878845) Escherichia coli O104:H4 str. 2011C-3493 13702328 YP_006780461.1 CDS O3K_18950 NC_018658.1 3879014 3879892 R COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; tartronate semialdehyde reductase complement(3879014..3879892) Escherichia coli O104:H4 str. 2011C-3493 13702329 YP_006780462.1 CDS O3K_18955 NC_018658.1 3879992 3880768 R COG3622 Hydroxypyruvate isomerase; hydroxypyruvate isomerase complement(3879992..3880768) Escherichia coli O104:H4 str. 2011C-3493 13702330 YP_006780463.1 CDS O3K_18960 NC_018658.1 3880781 3882562 R COG3960 Glyoxylate carboligase; glyoxylate carboligase complement(3880781..3882562) Escherichia coli O104:H4 str. 2011C-3493 13702331 YP_006780464.1 CDS O3K_18965 NC_018658.1 3882652 3883467 R COG1414 Transcriptional regulator; DNA-binding transcriptional repressor AllR complement(3882652..3883467) Escherichia coli O104:H4 str. 2011C-3493 13702332 YP_006780465.1 CDS O3K_18970 NC_018658.1 3883545 3884027 R COG3194 Ureidoglycolate hydrolase; ureidoglycolate hydrolase complement(3883545..3884027) Escherichia coli O104:H4 str. 2011C-3493 13702333 YP_006780466.1 CDS O3K_18975 NC_018658.1 3884257 3885183 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator AllS 3884257..3885183 Escherichia coli O104:H4 str. 2011C-3493 13702334 YP_006780467.1 CDS O3K_18980 NC_018658.1 3885252 3886346 D COG2603 Predicted ATPase; tRNA 2-selenouridine synthase 3885252..3886346 Escherichia coli O104:H4 str. 2011C-3493 13702335 YP_006780468.1 CDS O3K_18985 NC_018658.1 3886462 3886860 D putative regulator with homeodomain-like DNA binding domain; transposase 3886462..3886860 Escherichia coli O104:H4 str. 2011C-3493 13702336 YP_006780469.1 CDS O3K_18990 NC_018658.1 3887347 3887838 R hypothetical protein complement(3887347..3887838) Escherichia coli O104:H4 str. 2011C-3493 13702337 YP_006780470.1 CDS O3K_18995 NC_018658.1 3887819 3888529 R COG3209 Rhs family protein; rhs-like protein complement(3887819..3888529) Escherichia coli O104:H4 str. 2011C-3493 13702338 YP_006780471.1 CDS O3K_19000 NC_018658.1 3888529 3888897 R hypothetical protein complement(3888529..3888897) Escherichia coli O104:H4 str. 2011C-3493 13702339 YP_006780472.1 CDS O3K_19005 NC_018658.1 3888937 3893226 R COG3209 Rhs family protein; rhsD element protein complement(3888937..3893226) Escherichia coli O104:H4 str. 2011C-3493 13702340 YP_006780473.1 CDS O3K_19010 NC_018658.1 3893656 3896070 R COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component; ABC transporter permease complement(3893656..3896070) Escherichia coli O104:H4 str. 2011C-3493 13702341 YP_006780474.1 CDS O3K_19015 NC_018658.1 3896067 3896753 R COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component; ABC transporter ATP-binding protein YbbA complement(3896067..3896753) Escherichia coli O104:H4 str. 2011C-3493 13702342 YP_006780475.1 CDS O3K_19020 NC_018658.1 3896721 3897347 D COG2755 Lysophospholipase L1 and related esterases; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 3896721..3897347 Escherichia coli O104:H4 str. 2011C-3493 13702343 YP_006780476.1 CDS O3K_19025 NC_018658.1 3897376 3898146 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 3897376..3898146 Escherichia coli O104:H4 str. 2011C-3493 13702344 YP_006780477.1 CDS O3K_19030 NC_018658.1 3898207 3899061 D COG3118 Thioredoxin domain-containing protein; thioredoxin-like protein 3898207..3899061 Escherichia coli O104:H4 str. 2011C-3493 13702345 YP_006780478.1 CDS O3K_19035 NC_018658.1 3899124 3899903 R COG0390 ABC-type uncharacterized transport system, permease component; putative metal resistance protein complement(3899124..3899903) Escherichia coli O104:H4 str. 2011C-3493 13702346 YP_006780479.1 CDS O3K_19040 NC_018658.1 3899890 3900567 R COG4619 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATP-binding protein YbbL complement(3899890..3900567) Escherichia coli O104:H4 str. 2011C-3493 13702347 YP_006780480.1 CDS O3K_19045 NC_018658.1 3900713 3901630 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; protease 3900713..3901630 Escherichia coli O104:H4 str. 2011C-3493 13702348 YP_006780481.1 CDS O3K_19050 NC_018658.1 3901627 3902085 D COG1585 Membrane protein implicated in regulation of membrane protease activity; nodulation efficiency family protein 3901627..3902085 Escherichia coli O104:H4 str. 2011C-3493 13702349 YP_006780482.1 CDS O3K_19055 NC_018658.1 3902086 3902493 R COG0789 Predicted transcriptional regulators; DNA-binding transcriptional regulator CueR complement(3902086..3902493) Escherichia coli O104:H4 str. 2011C-3493 13702350 YP_006780483.1 CDS O3K_19060 NC_018658.1 3902618 3903910 R COG0531 Amino acid transporters; transporter complement(3902618..3903910) Escherichia coli O104:H4 str. 2011C-3493 13702351 YP_006780484.1 CDS O3K_19065 NC_018658.1 3903913 3904845 R COG2066 Glutaminase; glutaminase complement(3903913..3904845) Escherichia coli O104:H4 str. 2011C-3493 13702352 YP_006780485.1 CDS copA NC_018658.1 3905107 3907611 D COG2217 Cation transport ATPase; copper exporting ATPase 3905107..3907611 Escherichia coli O104:H4 str. 2011C-3493 13702353 YP_006780486.1 CDS O3K_19075 NC_018658.1 3907725 3908066 R COG3093 Plasmid maintenance system antidote protein; DNA-binding transcriptional regulator complement(3907725..3908066) Escherichia coli O104:H4 str. 2011C-3493 13702354 YP_006780487.1 CDS O3K_19080 NC_018658.1 3908204 3908998 D COG3735 Uncharacterized protein conserved in bacteria; hypothetical protein 3908204..3908998 Escherichia coli O104:H4 str. 2011C-3493 13702355 YP_006780488.1 CDS O3K_19085 NC_018658.1 3909202 3909681 D COG2606 Uncharacterized conserved protein; hypothetical protein 3909202..3909681 Escherichia coli O104:H4 str. 2011C-3493 13702356 YP_006780489.1 CDS ushA NC_018658.1 3909718 3911370 R COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; bifunctional UDP-sugar hydrolase/5'-nucleotidase complement(3909718..3911370) Escherichia coli O104:H4 str. 2011C-3493 13702357 YP_006780490.1 CDS O3K_19095 NC_018658.1 3911588 3912808 D COG0477 Permeases of the major facilitator superfamily; fosmidomycin efflux system, member of the major facilitator superfamily protein 3911588..3912808 Escherichia coli O104:H4 str. 2011C-3493 13702358 YP_006780491.1 CDS O3K_19100 NC_018658.1 3913046 3914722 D COG4651 Kef-type K+ transport system, predicted NAD-binding component; putative cation:proton antiport protein 3913046..3914722 Escherichia coli O104:H4 str. 2011C-3493 13702359 YP_006780492.1 CDS O3K_19105 NC_018658.1 3914855 3916159 R COG0524 Sugar kinases, ribokinase family; inosine/guanosine kinase complement(3914855..3916159) Escherichia coli O104:H4 str. 2011C-3493 13702360 YP_006780493.1 CDS O3K_19110 NC_018658.1 3916311 3917270 D COG0657 Esterase/lipase; acetyl esterase 3916311..3917270 Escherichia coli O104:H4 str. 2011C-3493 13702361 YP_006780494.1 CDS hemH NC_018658.1 3917267 3918229 R COG0276 Protoheme ferro-lyase (ferrochelatase); ferrochelatase complement(3917267..3918229) Escherichia coli O104:H4 str. 2011C-3493 13702362 YP_006780495.1 CDS adk NC_018658.1 3918465 3919109 R COG0563 Adenylate kinase and related kinases; adenylate kinase complement(3918465..3919109) Escherichia coli O104:H4 str. 2011C-3493 13702363 YP_006780496.1 CDS O3K_19125 NC_018658.1 3919290 3921164 R COG0326 Molecular chaperone, HSP90 family; heat shock protein 90 complement(3919290..3921164) Escherichia coli O104:H4 str. 2011C-3493 13702364 YP_006780497.1 CDS recR NC_018658.1 3921274 3921879 R COG0353 Recombinational DNA repair protein (RecF pathway); recombination protein RecR complement(3921274..3921879) Escherichia coli O104:H4 str. 2011C-3493 13702365 YP_006780498.1 CDS O3K_19135 NC_018658.1 3921879 3922208 R COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3921879..3922208) Escherichia coli O104:H4 str. 2011C-3493 13702366 YP_006780499.1 CDS O3K_19140 NC_018658.1 3922261 3924192 R COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunits gamma and tau complement(3922261..3924192) Escherichia coli O104:H4 str. 2011C-3493 13702367 YP_006780500.1 CDS O3K_19145 NC_018658.1 3924321 3924872 R COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine phosphoribosyltransferase complement(3924321..3924872) Escherichia coli O104:H4 str. 2011C-3493 13702368 YP_006780501.1 CDS O3K_19150 NC_018658.1 3925025 3925402 R COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3925025..3925402) Escherichia coli O104:H4 str. 2011C-3493 13702369 YP_006780502.1 CDS O3K_19155 NC_018658.1 3925472 3925999 D COG3923 Primosomal replication protein N''; primosomal replication protein N'' 3925472..3925999 Escherichia coli O104:H4 str. 2011C-3493 13702370 YP_006780503.1 CDS O3K_19160 NC_018658.1 3926013 3926174 D hypothetical protein 3926013..3926174 Escherichia coli O104:H4 str. 2011C-3493 13702371 YP_006780504.1 CDS O3K_19165 NC_018658.1 3926208 3926351 D hypothetical protein 3926208..3926351 Escherichia coli O104:H4 str. 2011C-3493 13702372 YP_006780505.1 CDS O3K_19170 NC_018658.1 3926386 3929748 R COG3264 Small-conductance mechanosensitive channel; hypothetical protein complement(3926386..3929748) Escherichia coli O104:H4 str. 2011C-3493 13702373 YP_006780506.1 CDS O3K_19175 NC_018658.1 3929876 3930523 R COG1309 Transcriptional regulator; DNA-binding transcriptional repressor AcrR complement(3929876..3930523) Escherichia coli O104:H4 str. 2011C-3493 13702374 YP_006780507.1 CDS O3K_19180 NC_018658.1 3930665 3931858 D COG0845 Membrane-fusion protein; multidrug efflux system transporter AcrA 3930665..3931858 Escherichia coli O104:H4 str. 2011C-3493 13702375 YP_006780508.1 CDS O3K_19185 NC_018658.1 3931881 3935030 D COG0841 Cation/multidrug efflux pump; multidrug efflux system protein AcrB 3931881..3935030 Escherichia coli O104:H4 str. 2011C-3493 13702376 YP_006780509.1 CDS O3K_19190 NC_018658.1 3935576 3935950 D Hha toxicity attenuator 3935576..3935950 Escherichia coli O104:H4 str. 2011C-3493 13702444 YP_006780510.1 CDS O3K_19195 NC_018658.1 3935976 3936194 D modulator of gene expression, with H-NS; hemolysin expression-modulating protein 3935976..3936194 Escherichia coli O104:H4 str. 2011C-3493 13702445 YP_006780511.1 CDS O3K_19200 NC_018658.1 3936365 3936916 D COG0110 Acetyltransferase (isoleucine patch superfamily); maltose O-acetyltransferase 3936365..3936916 Escherichia coli O104:H4 str. 2011C-3493 13702446 YP_006780512.1 CDS O3K_19205 NC_018658.1 3937032 3937502 D hypothetical protein 3937032..3937502 Escherichia coli O104:H4 str. 2011C-3493 13702447 YP_006780513.1 CDS O3K_19210 NC_018658.1 3937666 3939216 D COG4943 Predicted signal transduction protein containing sensor and EAL domains; hypothetical protein 3937666..3939216 Escherichia coli O104:H4 str. 2011C-3493 13702448 YP_006780514.1 CDS O3K_19215 NC_018658.1 3939258 3939611 R COG5507 Uncharacterized conserved protein; hypothetical protein complement(3939258..3939611) Escherichia coli O104:H4 str. 2011C-3493 13702449 YP_006780515.1 CDS O3K_19220 NC_018658.1 3939912 3940301 D COG3695 Predicted methylated DNA-protein cysteine methyltransferase; methylated-DNA-[protein]-cysteine S-methyltransferase 3939912..3940301 Escherichia coli O104:H4 str. 2011C-3493 13702450 YP_006780516.1 CDS O3K_19225 NC_018658.1 3940332 3940904 R COG3126 Uncharacterized protein conserved in bacteria; lipoprotein complement(3940332..3940904) Escherichia coli O104:H4 str. 2011C-3493 13702451 YP_006780517.1 CDS O3K_19230 NC_018658.1 3941122 3941982 D COG1946 Acyl-CoA thioesterase; acyl-CoA thioesterase II 3941122..3941982 Escherichia coli O104:H4 str. 2011C-3493 13702452 YP_006780518.1 CDS O3K_19235 NC_018658.1 3942031 3943317 R COG0004 Ammonia permease; ammonium transporter complement(3942031..3943317) Escherichia coli O104:H4 str. 2011C-3493 13702453 YP_006780519.1 CDS O3K_19240 NC_018658.1 3943347 3943685 R COG0347 Nitrogen regulatory protein PII; glutamine synthetase complement(3943347..3943685) Escherichia coli O104:H4 str. 2011C-3493 13702454 YP_006780520.1 CDS O3K_19245 NC_018658.1 3943866 3945647 R COG1132 ABC-type multidrug transport system, ATPase and permease components; putative multidrug transporter membrane\ATP-binding protein complement(3943866..3945647) Escherichia coli O104:H4 str. 2011C-3493 13702455 YP_006780521.1 CDS O3K_19250 NC_018658.1 3945640 3947412 R COG1132 ABC-type multidrug transport system, ATPase and permease components; putative multidrug transporter membrane\ATP-binding protein complement(3945640..3947412) Escherichia coli O104:H4 str. 2011C-3493 13702456 YP_006780522.1 CDS O3K_19255 NC_018658.1 3947442 3947900 R COG1522 Transcriptional regulators; putative LRP-like transcriptional regulator complement(3947442..3947900) Escherichia coli O104:H4 str. 2011C-3493 13702457 YP_006780523.1 CDS O3K_19260 NC_018658.1 3948053 3948871 R COG0561 Predicted hydrolases of the HAD superfamily; thiamin pyrimidine pyrophosphate hydrolase complement(3948053..3948871) Escherichia coli O104:H4 str. 2011C-3493 13702458 YP_006780524.1 CDS O3K_19265 NC_018658.1 3948971 3950671 D COG4533 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein 3948971..3950671 Escherichia coli O104:H4 str. 2011C-3493 13702459 YP_006780525.1 CDS O3K_19270 NC_018658.1 3950736 3951431 D COG0603 Predicted PP-loop superfamily ATPase; queuosine biosynthesis protein QueC 3950736..3951431 Escherichia coli O104:H4 str. 2011C-3493 13702460 YP_006780526.1 CDS O3K_19275 NC_018658.1 3951483 3951881 R COG0824 Predicted thioesterase; thioesterase superfamily protein complement(3951483..3951881) Escherichia coli O104:H4 str. 2011C-3493 13702461 YP_006780527.1 CDS O3K_19280 NC_018658.1 3951975 3952346 R COG1555 DNA uptake protein and related DNA-binding proteins; hypothetical protein complement(3951975..3952346) Escherichia coli O104:H4 str. 2011C-3493 13702462 YP_006780528.1 CDS O3K_19285 NC_018658.1 3952497 3954368 R COG0760 Parvulin-like peptidyl-prolyl isomerase; chaperone complement(3952497..3954368) Escherichia coli O104:H4 str. 2011C-3493 13702463 YP_006780529.1 CDS O3K_19290 NC_018658.1 3954560 3954832 R COG0776 Bacterial nucleoid DNA-binding protein; transcriptional regulator HU subunit beta complement(3954560..3954832) Escherichia coli O104:H4 str. 2011C-3493 13702464 YP_006780530.1 CDS O3K_19295 NC_018658.1 3955041 3957395 R COG0466 ATP-dependent Lon protease, bacterial type; DNA-binding ATP-dependent protease La complement(3955041..3957395) Escherichia coli O104:H4 str. 2011C-3493 13702465 YP_006780531.1 CDS clpX NC_018658.1 3957583 3958857 R COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease ATP-binding subunit ClpX complement(3957583..3958857) Escherichia coli O104:H4 str. 2011C-3493 13702466 YP_006780532.1 CDS clpP NC_018658.1 3958983 3959606 R COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease proteolytic subunit complement(3958983..3959606) Escherichia coli O104:H4 str. 2011C-3493 13702467 YP_006780533.1 CDS tig NC_018658.1 3959852 3961150 R COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); trigger factor complement(3959852..3961150) Escherichia coli O104:H4 str. 2011C-3493 13702468 YP_006780534.1 CDS O3K_19315 NC_018658.1 3961494 3961811 R COG0271 Stress-induced morphogen (activity unknown); transcriptional regulator BolA complement(3961494..3961811) Escherichia coli O104:H4 str. 2011C-3493 13702469 YP_006780535.1 CDS O3K_19320 NC_018658.1 3962116 3962694 D COG3056 Uncharacterized lipoprotein; hypothetical protein 3962116..3962694 Escherichia coli O104:H4 str. 2011C-3493 13702470 YP_006780536.1 CDS ampG NC_018658.1 3962738 3964213 D COG0477 Permeases of the major facilitator superfamily; muropeptide transporter 3962738..3964213 Escherichia coli O104:H4 str. 2011C-3493 13702471 YP_006780537.1 CDS O3K_19330 NC_018658.1 3964673 3965620 D COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome o ubiquinol oxidase subunit II 3964673..3965620 Escherichia coli O104:H4 str. 2011C-3493 13702472 YP_006780538.1 CDS O3K_19335 NC_018658.1 3965642 3967633 D COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome o ubiquinol oxidase subunit I 3965642..3967633 Escherichia coli O104:H4 str. 2011C-3493 13702473 YP_006780539.1 CDS O3K_19340 NC_018658.1 3967623 3968237 D COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; cytochrome o ubiquinol oxidase subunit III 3967623..3968237 Escherichia coli O104:H4 str. 2011C-3493 13702474 YP_006780540.1 CDS O3K_19345 NC_018658.1 3968237 3968566 D COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4; cytochrome o ubiquinol oxidase subunit IV 3968237..3968566 Escherichia coli O104:H4 str. 2011C-3493 13702475 YP_006780541.1 CDS O3K_19350 NC_018658.1 3968578 3969468 D COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor); protoheme IX farnesyltransferase 3968578..3969468 Escherichia coli O104:H4 str. 2011C-3493 13702476 YP_006780542.1 CDS O3K_19355 NC_018658.1 3969653 3969964 D COG4453 Uncharacterized protein conserved in bacteria; hypothetical protein 3969653..3969964 Escherichia coli O104:H4 str. 2011C-3493 13702477 YP_006780543.1 CDS O3K_19360 NC_018658.1 3969948 3970490 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 3969948..3970490 Escherichia coli O104:H4 str. 2011C-3493 13702478 YP_006780544.1 CDS O3K_19365 NC_018658.1 3970546 3971541 R COG0790 FOG: TPR repeat, SEL1 subfamily; zinc-dependent hydrolase complement(3970546..3971541) Escherichia coli O104:H4 str. 2011C-3493 13702479 YP_006780545.1 CDS O3K_19370 NC_018658.1 3971889 3973253 D COG0477 Permeases of the major facilitator superfamily; major facilitator family transporter protein 3971889..3973253 Escherichia coli O104:H4 str. 2011C-3493 13702480 YP_006780546.1 CDS O3K_19375 NC_018658.1 3973381 3973872 R COG1666 Uncharacterized protein conserved in bacteria; putative nucleotide-binding protein complement(3973381..3973872) Escherichia coli O104:H4 str. 2011C-3493 13702481 YP_006780547.1 CDS O3K_19380 NC_018658.1 3974040 3974951 D COG1893 Ketopantoate reductase; 2-dehydropantoate 2-reductase 3974040..3974951 Escherichia coli O104:H4 str. 2011C-3493 13702482 YP_006780548.1 CDS O3K_19385 NC_018658.1 3974914 3975504 D COG0693 Putative intracellular protease/amidase; oxidative-stress-resistance chaperone 3974914..3975504 Escherichia coli O104:H4 str. 2011C-3493 13702483 YP_006780549.1 CDS O3K_19390 NC_018658.1 3975558 3977006 R COG0301 Thiamine biosynthesis ATP pyrophosphatase; tRNA s(4)U8 sulfurtransferase complement(3975558..3977006) Escherichia coli O104:H4 str. 2011C-3493 13702484 YP_006780550.1 CDS O3K_19395 NC_018658.1 3977212 3977454 D COG1722 Exonuclease VII small subunit; exodeoxyribonuclease VII small subunit 3977212..3977454 Escherichia coli O104:H4 str. 2011C-3493 13702485 YP_006780551.1 CDS O3K_19400 NC_018658.1 3977454 3978353 D COG0142 Geranylgeranyl pyrophosphate synthase; geranyltranstransferase 3977454..3978353 Escherichia coli O104:H4 str. 2011C-3493 13702486 YP_006780552.1 CDS O3K_19405 NC_018658.1 3978378 3980240 D COG1154 Deoxyxylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 3978378..3980240 Escherichia coli O104:H4 str. 2011C-3493 13702487 YP_006780553.1 CDS O3K_19410 NC_018658.1 3980295 3981269 D COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 3980295..3981269 Escherichia coli O104:H4 str. 2011C-3493 13702488 YP_006780554.1 CDS O3K_19415 NC_018658.1 3981323 3981841 R COG1267 Phosphatidylglycerophosphatase A and related proteins; phosphatidylglycerophosphatase A complement(3981323..3981841) Escherichia coli O104:H4 str. 2011C-3493 13702489 YP_006780555.1 CDS O3K_19420 NC_018658.1 3981819 3982796 R COG0611 Thiamine monophosphate kinase; thiamine monophosphate kinase complement(3981819..3982796) Escherichia coli O104:H4 str. 2011C-3493 13702490 YP_006780556.1 CDS nusB NC_018658.1 3982874 3983293 R COG0781 Transcription termination factor; transcription antitermination protein NusB complement(3982874..3983293) Escherichia coli O104:H4 str. 2011C-3493 13702491 YP_006780557.1 CDS ribH NC_018658.1 3983313 3983783 R COG0054 Riboflavin synthase beta-chain; 6,7-dimethyl-8-ribityllumazine synthase complement(3983313..3983783) Escherichia coli O104:H4 str. 2011C-3493 13702492 YP_006780558.1 CDS ribD NC_018658.1 3983872 3984975 R COG0117 Pyrimidine deaminase; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase complement(3983872..3984975) Escherichia coli O104:H4 str. 2011C-3493 13702493 YP_006780559.1 CDS nrdR NC_018658.1 3984979 3985428 R COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; transcriptional regulator NrdR complement(3984979..3985428) Escherichia coli O104:H4 str. 2011C-3493 13702494 YP_006780560.1 CDS O3K_19455 NC_018658.1 3986417 3987301 D COG3248 Nucleoside-binding outer membrane protein; nucleoside-specific channel-forming protein Tsx 3986417..3987301 Escherichia coli O104:H4 str. 2011C-3493 13702495 YP_006780561.1 CDS O3K_19460 NC_018658.1 3987342 3987464 R hypothetical protein complement(3987342..3987464) Escherichia coli O104:H4 str. 2011C-3493 13702496 YP_006780562.1 CDS O3K_19465 NC_018658.1 3987478 3987825 R COG1403 Restriction endonuclease; hypothetical protein complement(3987478..3987825) Escherichia coli O104:H4 str. 2011C-3493 13702497 YP_006780563.1 CDS secF NC_018658.1 3987954 3988925 R COG0341 Preprotein translocase subunit SecF; preprotein translocase subunit SecF complement(3987954..3988925) Escherichia coli O104:H4 str. 2011C-3493 13702498 YP_006780564.1 CDS secD NC_018658.1 3988936 3990783 R COG0342 Preprotein translocase subunit SecD; preprotein translocase subunit SecD complement(3988936..3990783) Escherichia coli O104:H4 str. 2011C-3493 13702499 YP_006780565.1 CDS yajC NC_018658.1 3990811 3991143 R COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC complement(3990811..3991143) Escherichia coli O104:H4 str. 2011C-3493 13702500 YP_006780566.1 CDS tgt NC_018658.1 3991166 3992293 R COG0343 Queuine/archaeosine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase complement(3991166..3992293) Escherichia coli O104:H4 str. 2011C-3493 13702501 YP_006780567.1 CDS queA NC_018658.1 3992349 3993419 R COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(3992349..3993419) Escherichia coli O104:H4 str. 2011C-3493 13702502 YP_006780568.1 CDS O3K_19495 NC_018658.1 3993512 3994093 D COG3124 Uncharacterized protein conserved in bacteria; acyl carrier protein phosphodiesterase 3993512..3994093 Escherichia coli O104:H4 str. 2011C-3493 13702503 YP_006780569.1 CDS O3K_19500 NC_018658.1 3994098 3995915 R COG0366 Glycosidases; maltodextrin glucosidase complement(3994098..3995915) Escherichia coli O104:H4 str. 2011C-3493 13702504 YP_006780570.1 CDS proY NC_018658.1 3996071 3997444 R COG1113 Gamma-aminobutyrate permease and related permeases; putative proline-specific permease complement(3996071..3997444) Escherichia coli O104:H4 str. 2011C-3493 13702505 YP_006780571.1 CDS O3K_19510 NC_018658.1 3997520 3998839 R COG1114 Branched-chain amino acid permeases; branched-chain amino acid transport system 2 carrier protein BrnQ complement(3997520..3998839) Escherichia coli O104:H4 str. 2011C-3493 13702506 YP_006780572.1 CDS phoR NC_018658.1 3999246 4000541 R COG0642 Signal transduction histidine kinase; phosphate regulon sensor protein complement(3999246..4000541) Escherichia coli O104:H4 str. 2011C-3493 13702507 YP_006780573.1 CDS O3K_19520 NC_018658.1 4000599 4001288 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator PhoB complement(4000599..4001288) Escherichia coli O104:H4 str. 2011C-3493 13702508 YP_006780574.1 CDS O3K_19525 NC_018658.1 4001478 4002680 D COG0420 DNA repair exonuclease; exonuclease subunit SbcD 4001478..4002680 Escherichia coli O104:H4 str. 2011C-3493 13702509 YP_006780575.1 CDS O3K_19530 NC_018658.1 4002677 4005820 D COG0419 ATPase involved in DNA repair; exonuclease subunit SbcC 4002677..4005820 Escherichia coli O104:H4 str. 2011C-3493 13702510 YP_006780576.1 CDS O3K_19535 NC_018658.1 4005946 4007130 D COG2814 Arabinose efflux permease; MFS transport protein AraJ 4005946..4007130 Escherichia coli O104:H4 str. 2011C-3493 13702511 YP_006780577.1 CDS O3K_19540 NC_018658.1 4007273 4008181 R COG1940 Transcriptional regulator/sugar kinase; fructokinase complement(4007273..4008181) Escherichia coli O104:H4 str. 2011C-3493 13702512 YP_006780578.1 CDS O3K_19545 NC_018658.1 4008306 4009217 D COG2974 DNA recombination-dependent growth factor C; exonuclease RdgC 4008306..4009217 Escherichia coli O104:H4 str. 2011C-3493 13702513 YP_006780579.1 CDS O3K_19550 NC_018658.1 4009295 4009657 R hypothetical protein complement(4009295..4009657) Escherichia coli O104:H4 str. 2011C-3493 13702514 YP_006780580.1 CDS O3K_19555 NC_018658.1 4009918 4010202 R COG3123 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4009918..4010202) Escherichia coli O104:H4 str. 2011C-3493 13702584 YP_006780581.1 CDS O3K_19560 NC_018658.1 4010274 4010951 R hypothetical protein complement(4010274..4010951) Escherichia coli O104:H4 str. 2011C-3493 13702585 YP_006780582.1 CDS O3K_19565 NC_018658.1 4011209 4011400 R hypothetical protein complement(4011209..4011400) Escherichia coli O104:H4 str. 2011C-3493 13702586 YP_006780583.1 CDS aroL NC_018658.1 4011450 4011974 R COG0703 Shikimate kinase; shikimate kinase complement(4011450..4011974) Escherichia coli O104:H4 str. 2011C-3493 13702587 YP_006780584.1 CDS O3K_19575 NC_018658.1 4012157 4012615 R COG1671 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4012157..4012615) Escherichia coli O104:H4 str. 2011C-3493 13702588 YP_006780585.1 CDS O3K_19580 NC_018658.1 4012735 4013544 D COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 4012735..4013544 Escherichia coli O104:H4 str. 2011C-3493 13702589 YP_006780586.1 CDS adrA NC_018658.1 4013561 4014676 R COG2199 FOG: GGDEF domain; diguanylate cyclase AdrA complement(4013561..4014676) Escherichia coli O104:H4 str. 2011C-3493 13702590 YP_006780587.1 CDS O3K_19590 NC_018658.1 4014778 4015098 R hypothetical protein complement(4014778..4015098) Escherichia coli O104:H4 str. 2011C-3493 13702591 YP_006780588.1 CDS O3K_19595 NC_018658.1 4015217 4016632 R COG1785 Alkaline phosphatase; alkaline phosphatase complement(4015217..4016632) Escherichia coli O104:H4 str. 2011C-3493 13702592 YP_006780589.1 CDS O3K_19600 NC_018658.1 4016733 4016993 R anti-RssB factor complement(4016733..4016993) Escherichia coli O104:H4 str. 2011C-3493 13702593 YP_006780590.1 CDS ddl NC_018658.1 4017456 4018550 D COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanine--D-alanine ligase 4017456..4018550 Escherichia coli O104:H4 str. 2011C-3493 13702594 YP_006780591.1 CDS O3K_19610 NC_018658.1 4018574 4018786 R hypothetical protein complement(4018574..4018786) Escherichia coli O104:H4 str. 2011C-3493 13702595 YP_006780592.1 CDS O3K_19615 NC_018658.1 4019046 4019354 D hypothetical protein 4019046..4019354 Escherichia coli O104:H4 str. 2011C-3493 13702596 YP_006780593.1 CDS O3K_19620 NC_018658.1 4019413 4020507 R DNA-binding transcriptional regulator complement(4019413..4020507) Escherichia coli O104:H4 str. 2011C-3493 13702597 YP_006780594.1 CDS O3K_19625 NC_018658.1 4020520 4021740 R COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components; microcin B17 transporter complement(4020520..4021740) Escherichia coli O104:H4 str. 2011C-3493 13702598 YP_006780595.1 CDS O3K_19630 NC_018658.1 4022092 4023249 D COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactam binding protein AmpH 4022092..4023249 Escherichia coli O104:H4 str. 2011C-3493 13702599 YP_006780596.1 CDS O3K_19635 NC_018658.1 4023250 4023873 R COG2186 Transcriptional regulators; putative DNA-binding transcriptional regulator complement(4023250..4023873) Escherichia coli O104:H4 str. 2011C-3493 13702600 YP_006780597.1 CDS O3K_19640 NC_018658.1 4023961 4026849 R COG3468 Type V secretory pathway, adhesin AidA; flagellin structural protein, protein complement(4023961..4026849) Escherichia coli O104:H4 str. 2011C-3493 13702601 YP_006780598.1 CDS O3K_19645 NC_018658.1 4027373 4028347 D COG0113 Delta-aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase 4027373..4028347 Escherichia coli O104:H4 str. 2011C-3493 13702602 YP_006780599.1 CDS tauD NC_018658.1 4028453 4029304 R COG2175 Probable taurine catabolism dioxygenase; taurine dioxygenase complement(4028453..4029304) Escherichia coli O104:H4 str. 2011C-3493 13702603 YP_006780600.1 CDS O3K_19655 NC_018658.1 4029301 4030128 R COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; taurine transporter subunit complement(4029301..4030128) Escherichia coli O104:H4 str. 2011C-3493 13702604 YP_006780601.1 CDS tauB NC_018658.1 4030125 4030892 R COG4525 ABC-type taurine transport system, ATPase component; taurine transporter ATP-binding subunit complement(4030125..4030892) Escherichia coli O104:H4 str. 2011C-3493 13702605 YP_006780602.1 CDS tauA NC_018658.1 4030905 4031867 R COG4521 ABC-type taurine transport system, periplasmic component; taurine transporter substrate binding subunit complement(4030905..4031867) Escherichia coli O104:H4 str. 2011C-3493 13702606 YP_006780603.1 CDS O3K_19670 NC_018658.1 4032483 4033154 D COG2120 Uncharacterized proteins, LmbE homologs; hypothetical protein 4032483..4033154 Escherichia coli O104:H4 str. 2011C-3493 13702607 YP_006780604.1 CDS O3K_19675 NC_018658.1 4033164 4034360 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; membrane-associated glycosyltransferase 4033164..4034360 Escherichia coli O104:H4 str. 2011C-3493 13702608 YP_006780605.1 CDS O3K_19680 NC_018658.1 4034479 4034919 D COG0110 Acetyltransferase (isoleucine patch superfamily); transferase 4034479..4034919 Escherichia coli O104:H4 str. 2011C-3493 13702609 YP_006780606.1 CDS O3K_19685 NC_018658.1 4034921 4035694 D hypothetical protein 4034921..4035694 Escherichia coli O104:H4 str. 2011C-3493 13702610 YP_006780607.1 CDS O3K_19690 NC_018658.1 4035880 4036155 D COG1937 Uncharacterized protein conserved in bacteria; regulator protein FrmR 4035880..4036155 Escherichia coli O104:H4 str. 2011C-3493 13702611 YP_006780608.1 CDS O3K_19695 NC_018658.1 4036190 4037299 D COG1062 Zn-dependent alcohol dehydrogenases, class III; S-(hydroxymethyl)glutathione dehydrogenase 4036190..4037299 Escherichia coli O104:H4 str. 2011C-3493 13702612 YP_006780609.1 CDS O3K_19700 NC_018658.1 4037392 4038225 D COG0627 Predicted esterase; S-formylglutathione hydrolase 4037392..4038225 Escherichia coli O104:H4 str. 2011C-3493 13702613 YP_006780610.1 CDS O3K_19705 NC_018658.1 4038452 4038991 R COG3122 Uncharacterized protein conserved in bacteria; nucleoprotein/polynucleotide-associated enzyme complement(4038452..4038991) Escherichia coli O104:H4 str. 2011C-3493 13702614 YP_006780611.1 CDS O3K_19710 NC_018658.1 4039093 4040304 R COG0477 Permeases of the major facilitator superfamily; putative 3-hydroxyphenylpropionic transporter MhpT complement(4039093..4040304) Escherichia coli O104:H4 str. 2011C-3493 13702615 YP_006780612.1 CDS O3K_19715 NC_018658.1 4040480 4041493 R COG0119 Isopropylmalate/homocitrate/citramalate synthases; 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase complement(4040480..4041493) Escherichia coli O104:H4 str. 2011C-3493 13702616 YP_006780613.1 CDS O3K_19720 NC_018658.1 4041490 4042440 R COG4569 Acetaldehyde dehydrogenase (acetylating); acetaldehyde dehydrogenase complement(4041490..4042440) Escherichia coli O104:H4 str. 2011C-3493 13702617 YP_006780614.1 CDS mhpD NC_018658.1 4042437 4043246 R COG3971 2-keto-4-pentenoate hydratase; 2-keto-4-pentenoate hydratase complement(4042437..4043246) Escherichia coli O104:H4 str. 2011C-3493 13702618 YP_006780615.1 CDS O3K_19730 NC_018658.1 4043256 4044137 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase complement(4043256..4044137) Escherichia coli O104:H4 str. 2011C-3493 13702619 YP_006780616.1 CDS mhpB NC_018658.1 4044140 4045084 R 3-(2,3-dihydroxyphenyl)propionate dioxygenase complement(4044140..4045084) Escherichia coli O104:H4 str. 2011C-3493 13702620 YP_006780617.1 CDS mhpA NC_018658.1 4045086 4046750 R COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 3-(3-hydroxyphenyl)propionate hydroxylase complement(4045086..4046750) Escherichia coli O104:H4 str. 2011C-3493 13702621 YP_006780618.1 CDS O3K_19745 NC_018658.1 4046827 4047774 D COG1414 Transcriptional regulator; DNA-binding transcriptional activator MhpR 4046827..4047774 Escherichia coli O104:H4 str. 2011C-3493 13702622 YP_006780619.1 CDS lacI NC_018658.1 4047851 4048933 D COG1609 Transcriptional regulators; lac repressor 4047851..4048933 Escherichia coli O104:H4 str. 2011C-3493 13702623 YP_006780620.1 CDS lacZ NC_018658.1 4049056 4052130 D COG3250 Beta-galactosidase/beta-glucuronidase; beta-D-galactosidase 4049056..4052130 Escherichia coli O104:H4 str. 2011C-3493 13702624 YP_006780621.1 CDS lacY NC_018658.1 4052182 4053435 D COG0477 Permeases of the major facilitator superfamily; galactoside permease 4052182..4053435 Escherichia coli O104:H4 str. 2011C-3493 13702625 YP_006780622.1 CDS lacA NC_018658.1 4053501 4054112 D COG0110 Acetyltransferase (isoleucine patch superfamily); galactoside O-acetyltransferase 4053501..4054112 Escherichia coli O104:H4 str. 2011C-3493 13702626 YP_006780623.1 CDS cynX NC_018658.1 4054215 4055369 R COG2807 Cyanate permease; putative cyanate transporter complement(4054215..4055369) Escherichia coli O104:H4 str. 2011C-3493 13702627 YP_006780624.1 CDS O3K_19775 NC_018658.1 4055402 4055872 R COG1513 Cyanate lyase; cyanate hydratase complement(4055402..4055872) Escherichia coli O104:H4 str. 2011C-3493 13702628 YP_006780625.1 CDS O3K_19780 NC_018658.1 4055903 4056562 R COG0288 Carbonic anhydrase; carbonate dehydratase complement(4055903..4056562) Escherichia coli O104:H4 str. 2011C-3493 13702629 YP_006780626.1 CDS O3K_19785 NC_018658.1 4056672 4057571 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator CynR 4056672..4057571 Escherichia coli O104:H4 str. 2011C-3493 13702630 YP_006780627.1 CDS O3K_19790 NC_018658.1 4057611 4058894 R COG0402 Cytosine deaminase and related metal-dependent hydrolases; cytosine deaminase complement(4057611..4058894) Escherichia coli O104:H4 str. 2011C-3493 13702631 YP_006780628.1 CDS codB NC_018658.1 4058884 4060143 R COG1457 Purine-cytosine permease and related proteins; cytosine permease complement(4058884..4060143) Escherichia coli O104:H4 str. 2011C-3493 13702632 YP_006780629.1 CDS prpE NC_018658.1 4060569 4062455 R COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; propionyl-CoA synthetase complement(4060569..4062455) Escherichia coli O104:H4 str. 2011C-3493 13702633 YP_006780630.1 CDS prpD NC_018658.1 4062495 4063946 R COG2079 Uncharacterized protein involved in propionate catabolism; 2-methylcitrate dehydratase complement(4062495..4063946) Escherichia coli O104:H4 str. 2011C-3493 13702634 YP_006780631.1 CDS O3K_19810 NC_018658.1 4063980 4065149 R COG0372 Citrate synthase; methylcitrate synthase complement(4063980..4065149) Escherichia coli O104:H4 str. 2011C-3493 13702635 YP_006780632.1 CDS prpB NC_018658.1 4065194 4066084 R COG2513 PEP phosphonomutase and related enzymes; 2-methylisocitrate lyase complement(4065194..4066084) Escherichia coli O104:H4 str. 2011C-3493 13702636 YP_006780633.1 CDS O3K_19820 NC_018658.1 4066322 4067908 D COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains; propionate catabolism operon regulatory protein PrpR 4066322..4067908 Escherichia coli O104:H4 str. 2011C-3493 13702637 YP_006780634.1 CDS O3K_19825 NC_018658.1 4068009 4068284 R hypothetical protein complement(4068009..4068284) Escherichia coli O104:H4 str. 2011C-3493 13702638 YP_006780635.1 CDS O3K_19830 NC_018658.1 4068470 4069102 D COG1280 Putative threonine efflux protein; neutral amino-acid efflux system 4068470..4069102 Escherichia coli O104:H4 str. 2011C-3493 13702639 YP_006780636.1 CDS O3K_19840 NC_018658.1 4069776 4070591 R hypothetical protein complement(4069776..4070591) Escherichia coli O104:H4 str. 2011C-3493 13702642 YP_006780637.1 CDS O3K_19845 NC_018658.1 4070834 4071883 R COG1064 Zn-dependent alcohol dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein complement(4070834..4071883) Escherichia coli O104:H4 str. 2011C-3493 13702643 YP_006780638.1 CDS O3K_19850 NC_018658.1 4071970 4072926 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease complement(4071970..4072926) Escherichia coli O104:H4 str. 2011C-3493 13702644 YP_006780639.1 CDS O3K_19855 NC_018658.1 4072923 4073894 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; permease of transporter probably ribose specific complement(4072923..4073894) Escherichia coli O104:H4 str. 2011C-3493 13702645 YP_006780640.1 CDS O3K_19860 NC_018658.1 4073887 4075371 R COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein complement(4073887..4075371) Escherichia coli O104:H4 str. 2011C-3493 13702646 YP_006780641.1 CDS O3K_19865 NC_018658.1 4075420 4076406 R COG1879 ABC-type sugar transport system, periplasmic component; sugar-binding protein complement(4075420..4076406) Escherichia coli O104:H4 str. 2011C-3493 13702647 YP_006780642.1 CDS O3K_19870 NC_018658.1 4076657 4077097 R COG4405 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4076657..4077097) Escherichia coli O104:H4 str. 2011C-3493 13702648 YP_006780643.1 CDS O3K_19885 NC_018658.1 4078758 4079708 R COG0549 Carbamate kinase; putative carbamate kinase complement(4078758..4079708) Escherichia coli O104:H4 str. 2011C-3493 13702649 YP_006780644.1 CDS O3K_19890 NC_018658.1 4079851 4081269 R hypothetical protein complement(4079851..4081269) Escherichia coli O104:H4 str. 2011C-3493 13702650 YP_006780645.1 CDS O3K_19895 NC_018658.1 4081269 4082816 R bacterial FdrA protein; COG0074 Succinyl-CoA synthetase, alpha subunit; acyl-CoA synthetase complement(4081269..4082816) Escherichia coli O104:H4 str. 2011C-3493 13702651 YP_006780646.1 CDS O3K_19900 NC_018658.1 4082806 4083669 R hypothetical protein complement(4082806..4083669) Escherichia coli O104:H4 str. 2011C-3493 13702652 YP_006780647.1 CDS O3K_19905 NC_018658.1 4083709 4084314 R COG0666 FOG: Ankyrin repeat; transcriptional regulator complement(4083709..4084314) Escherichia coli O104:H4 str. 2011C-3493 13702653 YP_006780648.1 CDS O3K_19910 NC_018658.1 4084572 4085069 D inner membrane protein 4084572..4085069 Escherichia coli O104:H4 str. 2011C-3493 13702654 YP_006780649.1 CDS O3K_19915 NC_018658.1 4085161 4086093 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 4085161..4086093 Escherichia coli O104:H4 str. 2011C-3493 13702655 YP_006780650.1 CDS O3K_19920 NC_018658.1 4086135 4087223 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative DNA-binding transcriptional regulator complement(4086135..4087223) Escherichia coli O104:H4 str. 2011C-3493 13703224 YP_006780651.1 CDS O3K_19925 NC_018658.1 4087365 4091348 R COG5295 Autotransporter adhesin; AidA-I adhesin-like protein complement(4087365..4091348) Escherichia coli O104:H4 str. 2011C-3493 13703225 YP_006780652.1 CDS O3K_19930 NC_018658.1 4091921 4093954 R COG1292 Choline-glycine betaine transporter; choline transport protein BetT complement(4091921..4093954) Escherichia coli O104:H4 str. 2011C-3493 13703226 YP_006780653.1 CDS O3K_19935 NC_018658.1 4094083 4094670 D COG1309 Transcriptional regulator; transcriptional regulator BetI 4094083..4094670 Escherichia coli O104:H4 str. 2011C-3493 13703227 YP_006780654.1 CDS O3K_19940 NC_018658.1 4094684 4096156 D COG1012 NAD-dependent aldehyde dehydrogenases; betaine aldehyde dehydrogenase 4094684..4096156 Escherichia coli O104:H4 str. 2011C-3493 13703228 YP_006780655.1 CDS O3K_19945 NC_018658.1 4096170 4097840 D COG2303 Choline dehydrogenase and related flavoproteins; choline dehydrogenase 4096170..4097840 Escherichia coli O104:H4 str. 2011C-3493 13703229 YP_006780656.1 CDS O3K_19950 NC_018658.1 4098053 4098718 D inner membrane protein 4098053..4098718 Escherichia coli O104:H4 str. 2011C-3493 13703230 YP_006780657.1 CDS O3K_19955 NC_018658.1 4098964 4099659 R COG1556 Uncharacterized conserved protein; hypothetical protein complement(4098964..4099659) Escherichia coli O104:H4 str. 2011C-3493 13703231 YP_006780658.1 CDS O3K_19960 NC_018658.1 4099652 4101079 R COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain; oxidoreductase subunit with NAD(P)-binding domain and ferredoxin-like domain complement(4099652..4101079) Escherichia coli O104:H4 str. 2011C-3493 13703232 YP_006780659.1 CDS O3K_19965 NC_018658.1 4101090 4101809 R COG0247 Fe-S oxidoreductase; oxidoreductase complement(4101090..4101809) Escherichia coli O104:H4 str. 2011C-3493 13703233 YP_006780660.1 CDS O3K_19970 NC_018658.1 4102336 4103190 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator, ARAC-type complement(4102336..4103190) Escherichia coli O104:H4 str. 2011C-3493 13703234 YP_006780661.1 CDS O3K_19975 NC_018658.1 4103416 4104741 D COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyridine nucleotide-disulfide oxidoreductase 4103416..4104741 Escherichia coli O104:H4 str. 2011C-3493 13703235 YP_006780662.1 CDS O3K_19980 NC_018658.1 4104850 4105086 D hypothetical protein 4104850..4105086 Escherichia coli O104:H4 str. 2011C-3493 13703236 YP_006780663.1 CDS O3K_19985 NC_018658.1 4105098 4105691 D COG3059 Predicted membrane protein; hypothetical protein 4105098..4105691 Escherichia coli O104:H4 str. 2011C-3493 13703237 YP_006780664.1 CDS O3K_19990 NC_018658.1 4106281 4107138 D COG2207 AraC-type DNA-binding domain-containing proteins; putative transcriptional regulator ykgA 4106281..4107138 Escherichia coli O104:H4 str. 2011C-3493 13703238 YP_006780665.1 CDS O3K_19995 NC_018658.1 4107259 4111512 R adhesin complement(4107259..4111512) Escherichia coli O104:H4 str. 2011C-3493 13703239 YP_006780666.1 CDS O3K_20000 NC_018658.1 4112628 4112729 D hypothetical protein 4112628..4112729 Escherichia coli O104:H4 str. 2011C-3493 13703240 YP_006780667.1 CDS rpmE2 NC_018658.1 4113093 4113356 D COG0254 Ribosomal protein L31; 50S ribosomal protein L31 4113093..4113356 Escherichia coli O104:H4 str. 2011C-3493 13703241 YP_006780668.1 CDS rpmJ NC_018658.1 4113356 4113496 D COG0257 Ribosomal protein L36; 50S ribosomal protein L36 4113356..4113496 Escherichia coli O104:H4 str. 2011C-3493 13703242 YP_006780669.1 CDS O3K_20015 NC_018658.1 4113531 4113758 R hypothetical protein complement(4113531..4113758) Escherichia coli O104:H4 str. 2011C-3493 13703243 YP_006780670.1 CDS O3K_20020 NC_018658.1 4114533 4115123 D COG2771 DNA-binding HTH domain-containing proteins; transcriptional regulator 4114533..4115123 Escherichia coli O104:H4 str. 2011C-3493 13703244 YP_006780671.1 CDS O3K_20025 NC_018658.1 4115198 4115785 D hypothetical protein 4115198..4115785 Escherichia coli O104:H4 str. 2011C-3493 13703245 YP_006780672.1 CDS O3K_20030 NC_018658.1 4115843 4116511 D chaperone 4115843..4116511 Escherichia coli O104:H4 str. 2011C-3493 13703246 YP_006780673.1 CDS O3K_20035 NC_018658.1 4116537 4119062 D hypothetical protein 4116537..4119062 Escherichia coli O104:H4 str. 2011C-3493 13703247 YP_006780674.1 CDS O3K_20040 NC_018658.1 4119052 4120695 D hypothetical protein 4119052..4120695 Escherichia coli O104:H4 str. 2011C-3493 13703248 YP_006780675.1 CDS O3K_20045 NC_018658.1 4120664 4121374 D hypothetical protein 4120664..4121374 Escherichia coli O104:H4 str. 2011C-3493 13703249 YP_006780676.1 CDS O3K_20050 NC_018658.1 4121687 4122016 D COG0727 Predicted Fe-S-cluster oxidoreductase; putative ferredoxin 4121687..4122016 Escherichia coli O104:H4 str. 2011C-3493 13703250 YP_006780677.1 CDS O3K_20055 NC_018658.1 4122264 4122878 R COG3477 Predicted periplasmic/secreted protein; hypothetical protein complement(4122264..4122878) Escherichia coli O104:H4 str. 2011C-3493 13703251 YP_006780678.1 CDS O3K_20060 NC_018658.1 4123296 4123985 D COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; aldehyde oxidoreductase 2Fe-2S subunit 4123296..4123985 Escherichia coli O104:H4 str. 2011C-3493 13703252 YP_006780679.1 CDS O3K_20065 NC_018658.1 4123982 4124938 D COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; oxidoreductase 4123982..4124938 Escherichia coli O104:H4 str. 2011C-3493 13703253 YP_006780680.1 CDS O3K_20070 NC_018658.1 4124935 4127133 D COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; oxidoreductase with molybdenum-binding domain 4124935..4127133 Escherichia coli O104:H4 str. 2011C-3493 13703254 YP_006780681.1 CDS O3K_20075 NC_018658.1 4127143 4128099 D COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 4127143..4128099 Escherichia coli O104:H4 str. 2011C-3493 13703255 YP_006780682.1 CDS O3K_20080 NC_018658.1 4128078 4128488 D COG0583 Transcriptional regulator; transcriptional regulator 4128078..4128488 Escherichia coli O104:H4 str. 2011C-3493 13703256 YP_006780683.1 CDS O3K_20085 NC_018658.1 4128948 4129928 R hypothetical protein complement(4128948..4129928) Escherichia coli O104:H4 str. 2011C-3493 13703257 YP_006780684.1 CDS O3K_20090 NC_018658.1 4129921 4130904 R COG1106 Predicted ATPases; hypothetical protein complement(4129921..4130904) Escherichia coli O104:H4 str. 2011C-3493 13703258 YP_006780685.1 CDS O3K_20095 NC_018658.1 4131520 4132047 R hypothetical protein complement(4131520..4132047) Escherichia coli O104:H4 str. 2011C-3493 13703259 YP_006780686.1 CDS O3K_20100 NC_018658.1 4132147 4132419 R hypothetical protein complement(4132147..4132419) Escherichia coli O104:H4 str. 2011C-3493 13703260 YP_006780687.1 CDS O3K_20105 NC_018658.1 4132416 4132583 R hypothetical protein complement(4132416..4132583) Escherichia coli O104:H4 str. 2011C-3493 13703261 YP_006780688.1 CDS O3K_20110 NC_018658.1 4132599 4132799 D hypothetical protein 4132599..4132799 Escherichia coli O104:H4 str. 2011C-3493 13703262 YP_006780689.1 CDS O3K_20115 NC_018658.1 4132862 4133185 R hypothetical protein complement(4132862..4133185) Escherichia coli O104:H4 str. 2011C-3493 13703263 YP_006780690.1 CDS O3K_20120 NC_018658.1 4133250 4134392 R hypothetical protein complement(4133250..4134392) Escherichia coli O104:H4 str. 2011C-3493 13703264 YP_006780691.1 CDS O3K_20125 NC_018658.1 4134527 4134814 R Protein perC (Protein bfpW) complement(4134527..4134814) Escherichia coli O104:H4 str. 2011C-3493 13703265 YP_006780692.1 CDS O3K_20130 NC_018658.1 4134811 4135341 R COG3109 Activator of osmoprotectant transporter ProP; Activator of ProP osmoprotectant transporter complement(4134811..4135341) Escherichia coli O104:H4 str. 2011C-3493 13703266 YP_006780693.1 CDS O3K_20135 NC_018658.1 4135827 4137959 R COG5519 Superfamily II helicase and inactivated derivatives; hypothetical protein complement(4135827..4137959) Escherichia coli O104:H4 str. 2011C-3493 13703267 YP_006780694.1 CDS O3K_20140 NC_018658.1 4137956 4138246 R hypothetical protein complement(4137956..4138246) Escherichia coli O104:H4 str. 2011C-3493 13703268 YP_006780695.1 CDS O3K_20145 NC_018658.1 4138251 4138451 R hypothetical protein complement(4138251..4138451) Escherichia coli O104:H4 str. 2011C-3493 13703269 YP_006780696.1 CDS O3K_20150 NC_018658.1 4138444 4138809 R hypothetical protein complement(4138444..4138809) Escherichia coli O104:H4 str. 2011C-3493 13703270 YP_006780697.1 CDS O3K_20155 NC_018658.1 4138820 4139167 R hypothetical protein complement(4138820..4139167) Escherichia coli O104:H4 str. 2011C-3493 13703271 YP_006780698.1 CDS O3K_20160 NC_018658.1 4139391 4139663 D hypothetical protein 4139391..4139663 Escherichia coli O104:H4 str. 2011C-3493 13703272 YP_006780699.1 CDS O3K_20165 NC_018658.1 4140381 4141181 R COG3561 Phage anti-repressor protein; AntA/AntB antirepressor complement(4140381..4141181) Escherichia coli O104:H4 str. 2011C-3493 13703273 YP_006780700.1 CDS O3K_20170 NC_018658.1 4141260 4141382 R COG3311 Predicted transcriptional regulator; Phage transcriptional regulator, AlpA complement(4141260..4141382) Escherichia coli O104:H4 str. 2011C-3493 13703274 YP_006780701.1 CDS O3K_20175 NC_018658.1 4141652 4142449 R hypothetical protein complement(4141652..4142449) Escherichia coli O104:H4 str. 2011C-3493 13703275 YP_006780702.1 CDS O3K_20180 NC_018658.1 4142578 4143792 R COG0582 Integrase; prophage CPS-53 integrase complement(4142578..4143792) Escherichia coli O104:H4 str. 2011C-3493 13703276 YP_006780703.1 CDS O3K_20185 NC_018658.1 4144120 4145397 D COG0582 Integrase; integrase 4144120..4145397 Escherichia coli O104:H4 str. 2011C-3493 13703277 YP_006780704.1 CDS O3K_20190 NC_018658.1 4145478 4146155 R hypothetical protein complement(4145478..4146155) Escherichia coli O104:H4 str. 2011C-3493 13703278 YP_006780705.1 CDS O3K_20195 NC_018658.1 4146203 4148044 R hypothetical protein complement(4146203..4148044) Escherichia coli O104:H4 str. 2011C-3493 13703279 YP_006780706.1 CDS O3K_20200 NC_018658.1 4148428 4149459 R hypothetical protein complement(4148428..4149459) Escherichia coli O104:H4 str. 2011C-3493 13703280 YP_006780707.1 CDS O3K_20205 NC_018658.1 4149474 4149857 R hypothetical protein complement(4149474..4149857) Escherichia coli O104:H4 str. 2011C-3493 13703281 YP_006780708.1 CDS O3K_20210 NC_018658.1 4149862 4150059 R hypothetical protein complement(4149862..4150059) Escherichia coli O104:H4 str. 2011C-3493 13703282 YP_006780709.1 CDS O3K_20215 NC_018658.1 4151050 4151349 R hypothetical protein complement(4151050..4151349) Escherichia coli O104:H4 str. 2011C-3493 13703283 YP_006780710.1 CDS O3K_20220 NC_018658.1 4151349 4151552 R hypothetical protein complement(4151349..4151552) Escherichia coli O104:H4 str. 2011C-3493 13703284 YP_006780711.1 CDS O3K_20225 NC_018658.1 4151610 4151993 R hypothetical protein complement(4151610..4151993) Escherichia coli O104:H4 str. 2011C-3493 13703285 YP_006780712.1 CDS O3K_20230 NC_018658.1 4152091 4152360 R hypothetical protein complement(4152091..4152360) Escherichia coli O104:H4 str. 2011C-3493 13703286 YP_006780713.1 CDS O3K_20235 NC_018658.1 4152370 4153038 R hypothetical protein complement(4152370..4153038) Escherichia coli O104:H4 str. 2011C-3493 13703287 YP_006780714.1 CDS O3K_20240 NC_018658.1 4155043 4155594 D COG1961 Site-specific recombinases, DNA invertase Pin homologs; resolvase domain-containing protein 4155043..4155594 Escherichia coli O104:H4 str. 2011C-3493 13703288 YP_006780715.1 CDS O3K_20245 NC_018658.1 4156160 4156312 R hypothetical protein complement(4156160..4156312) Escherichia coli O104:H4 str. 2011C-3493 13703289 YP_006780716.1 CDS proA NC_018658.1 4157109 4158362 R COG0014 Gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase complement(4157109..4158362) Escherichia coli O104:H4 str. 2011C-3493 13703291 YP_006780717.1 CDS O3K_20255 NC_018658.1 4158374 4159477 R COG0263 Glutamate 5-kinase; gamma-glutamyl kinase complement(4158374..4159477) Escherichia coli O104:H4 str. 2011C-3493 13703292 YP_006780718.1 CDS O3K_20260 NC_018658.1 4159765 4160820 D COG3203 Outer membrane protein (porin); outer membrane phosphoporin protein E 4159765..4160820 Escherichia coli O104:H4 str. 2011C-3493 13703293 YP_006780719.1 CDS O3K_20265 NC_018658.1 4160859 4161260 R DNA-binding transcriptional regulator Crl complement(4160859..4161260) Escherichia coli O104:H4 str. 2011C-3493 13703294 YP_006780720.1 CDS frsA NC_018658.1 4161318 4162562 R COG1073 Hydrolases of the alpha/beta superfamily; fermentation/respiration switch protein complement(4161318..4162562) Escherichia coli O104:H4 str. 2011C-3493 13703295 YP_006780721.1 CDS O3K_20275 NC_018658.1 4162654 4163112 R COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; xanthine-guanine phosphoribosyltransferase complement(4162654..4163112) Escherichia coli O104:H4 str. 2011C-3493 13703296 YP_006780722.1 CDS O3K_20280 NC_018658.1 4163373 4164830 D COG2195 Di- and tripeptidases; aminoacyl-histidine dipeptidase 4163373..4164830 Escherichia coli O104:H4 str. 2011C-3493 13703297 YP_006780723.1 CDS prfH NC_018658.1 4164887 4165501 R COG1186 Protein chain release factor B; peptide chain release factor-like protein complement(4164887..4165501) Escherichia coli O104:H4 str. 2011C-3493 13703298 YP_006780724.1 CDS O3K_20290 NC_018658.1 4165498 4166637 R COG1690 Uncharacterized conserved protein; hypothetical protein complement(4165498..4166637) Escherichia coli O104:H4 str. 2011C-3493 13703299 YP_006780725.1 CDS O3K_20295 NC_018658.1 4166883 4167335 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative acyltransferase complement(4166883..4167335) Escherichia coli O104:H4 str. 2011C-3493 13703300 YP_006780726.1 CDS O3K_20300 NC_018658.1 4167332 4168387 R COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase IV complement(4167332..4168387) Escherichia coli O104:H4 str. 2011C-3493 13703301 YP_006780727.1 CDS O3K_20305 NC_018658.1 4168458 4169243 R COG1360 Flagellar motor protein; hypothetical protein complement(4168458..4169243) Escherichia coli O104:H4 str. 2011C-3493 13703302 YP_006780728.1 CDS O3K_20310 NC_018658.1 4169188 4170927 D COG1298 Flagellar biosynthesis pathway, component FlhA; flagellar system protein 4169188..4170927 Escherichia coli O104:H4 str. 2011C-3493 13703303 YP_006780729.1 CDS O3K_20315 NC_018658.1 4171032 4171310 D hypothetical protein 4171032..4171310 Escherichia coli O104:H4 str. 2011C-3493 13703304 YP_006780730.1 CDS O3K_20320 NC_018658.1 4171303 4171659 D COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters; putative HicB 4171303..4171659 Escherichia coli O104:H4 str. 2011C-3493 13703305 YP_006780731.1 CDS O3K_20325 NC_018658.1 4171716 4172465 R COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hydrolase complement(4171716..4172465) Escherichia coli O104:H4 str. 2011C-3493 13703306 YP_006780732.1 CDS O3K_20330 NC_018658.1 4172675 4172935 D COG3077 DNA-damage-inducible protein J; DNA-damage-inducible protein J 4172675..4172935 Escherichia coli O104:H4 str. 2011C-3493 13703307 YP_006780733.1 CDS O3K_20335 NC_018658.1 4172938 4173216 D COG3041 Uncharacterized protein conserved in bacteria; toxin of the YafQ-DinJ toxin-antitoxin system 4172938..4173216 Escherichia coli O104:H4 str. 2011C-3493 13703308 YP_006780734.1 CDS O3K_20340 NC_018658.1 4173372 4174112 D COG3034 Uncharacterized protein conserved in bacteria; hypothetical protein 4173372..4174112 Escherichia coli O104:H4 str. 2011C-3493 13703309 YP_006780735.1 CDS O3K_20345 NC_018658.1 4174083 4174850 R COG0121 Predicted glutamine amidotransferase; putative amidotransfease complement(4174083..4174850) Escherichia coli O104:H4 str. 2011C-3493 13703310 YP_006780736.1 CDS gmhA NC_018658.1 4175056 4175634 R COG0279 Phosphoheptose isomerase; phosphoheptose isomerase complement(4175056..4175634) Escherichia coli O104:H4 str. 2011C-3493 13703311 YP_006780737.1 CDS fadE NC_018658.1 4175874 4178318 D COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 4175874..4178318 Escherichia coli O104:H4 str. 2011C-3493 13703312 YP_006780738.1 CDS O3K_20360 NC_018658.1 4178361 4178834 R C-lysozyme inhibitor complement(4178361..4178834) Escherichia coli O104:H4 str. 2011C-3493 13703313 YP_006780739.1 CDS O3K_20365 NC_018658.1 4178988 4179758 D COG0388 Predicted amidohydrolase; C-N hydrolase family amidase 4178988..4179758 Escherichia coli O104:H4 str. 2011C-3493 13703314 YP_006780740.1 CDS O3K_20370 NC_018658.1 4179800 4180843 R COG5433 Transposase; transposase complement(4179800..4180843) Escherichia coli O104:H4 str. 2011C-3493 13703315 YP_006780741.1 CDS O3K_20385 NC_018658.1 4182346 4182828 R hypothetical protein complement(4182346..4182828) Escherichia coli O104:H4 str. 2011C-3493 13703316 YP_006780742.1 CDS O3K_20390 NC_018658.1 4182812 4184002 R COG3209 Rhs family protein; putative Rhs Core protein complement(4182812..4184002) Escherichia coli O104:H4 str. 2011C-3493 13703317 YP_006780743.1 CDS O3K_20395 NC_018658.1 4183971 4186475 R COG3209 Rhs family protein; Rhs core protein complement(4183971..4186475) Escherichia coli O104:H4 str. 2011C-3493 13703318 YP_006780744.1 CDS O3K_20400 NC_018658.1 4186551 4188692 R COG3501 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4186551..4188692) Escherichia coli O104:H4 str. 2011C-3493 13703319 YP_006780745.1 CDS O3K_20405 NC_018658.1 4188902 4189420 R COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein complement(4188902..4189420) Escherichia coli O104:H4 str. 2011C-3493 13703320 YP_006780746.1 CDS O3K_20410 NC_018658.1 4189547 4189690 R hypothetical protein complement(4189547..4189690) Escherichia coli O104:H4 str. 2011C-3493 13703321 YP_006780747.1 CDS O3K_20415 NC_018658.1 4190117 4190617 D COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 4190117..4190617 Escherichia coli O104:H4 str. 2011C-3493 13703322 YP_006780748.1 CDS O3K_20420 NC_018658.1 4190652 4190876 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 4190652..4190876 Escherichia coli O104:H4 str. 2011C-3493 13703323 YP_006780749.1 CDS O3K_20425 NC_018658.1 4190927 4192402 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 4190927..4192402 Escherichia coli O104:H4 str. 2011C-3493 13703324 YP_006780750.1 CDS O3K_20430 NC_018658.1 4192409 4192822 D COG3518 Uncharacterized protein conserved in bacteria; hypothetical protein 4192409..4192822 Escherichia coli O104:H4 str. 2011C-3493 13703325 YP_006780751.1 CDS O3K_20435 NC_018658.1 4192826 4194676 D COG3519 Uncharacterized protein conserved in bacteria; type VI secretion system protein ImpG 4192826..4194676 Escherichia coli O104:H4 str. 2011C-3493 13703326 YP_006780752.1 CDS O3K_20440 NC_018658.1 4194640 4195722 D COG3520 Uncharacterized protein conserved in bacteria; hypothetical protein 4194640..4195722 Escherichia coli O104:H4 str. 2011C-3493 13703327 YP_006780753.1 CDS O3K_20445 NC_018658.1 4195747 4197027 D COG3456 Uncharacterized conserved protein, contains FHA domain; type VI secretion system protein ImpI 4195747..4197027 Escherichia coli O104:H4 str. 2011C-3493 13703328 YP_006780754.1 CDS O3K_20450 NC_018658.1 4197024 4197548 D COG3521 Uncharacterized protein conserved in bacteria; lipoprotein 4197024..4197548 Escherichia coli O104:H4 str. 2011C-3493 13703329 YP_006780755.1 CDS O3K_20455 NC_018658.1 4197551 4198882 D COG3522 Uncharacterized protein conserved in bacteria; hypothetical protein 4197551..4198882 Escherichia coli O104:H4 str. 2011C-3493 13703330 YP_006780756.1 CDS O3K_20460 NC_018658.1 4198887 4199648 D COG3455 Uncharacterized protein conserved in bacteria; putative membrane protein Aec26 4198887..4199648 Escherichia coli O104:H4 str. 2011C-3493 13703331 YP_006780757.1 CDS O3K_20465 NC_018658.1 4199657 4202416 D COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp proteinase ATP-binding subunit 4199657..4202416 Escherichia coli O104:H4 str. 2011C-3493 13703332 YP_006780758.1 CDS O3K_20470 NC_018658.1 4202413 4203156 D hypothetical protein 4202413..4203156 Escherichia coli O104:H4 str. 2011C-3493 13703333 YP_006780759.1 CDS O3K_20475 NC_018658.1 4203161 4204576 D COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 4203161..4204576 Escherichia coli O104:H4 str. 2011C-3493 13703334 YP_006780760.1 CDS O3K_20480 NC_018658.1 4204595 4208119 D COG3523 Uncharacterized protein conserved in bacteria; IcmF-like protein 4204595..4208119 Escherichia coli O104:H4 str. 2011C-3493 13703335 YP_006780761.1 CDS O3K_20485 NC_018658.1 4208130 4209482 D COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 4208130..4209482 Escherichia coli O104:H4 str. 2011C-3493 13703336 YP_006780762.1 CDS O3K_20490 NC_018658.1 4209506 4209988 D COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein 4209506..4209988 Escherichia coli O104:H4 str. 2011C-3493 13703337 YP_006780763.1 CDS O3K_20495 NC_018658.1 4210032 4210946 D hypothetical protein 4210032..4210946 Escherichia coli O104:H4 str. 2011C-3493 13703338 YP_006780764.1 CDS O3K_20500 NC_018658.1 4210956 4211435 D hypothetical protein 4210956..4211435 Escherichia coli O104:H4 str. 2011C-3493 13703339 YP_006780765.1 CDS O3K_20505 NC_018658.1 4211572 4212357 R aminopeptidase complement(4211572..4212357) Escherichia coli O104:H4 str. 2011C-3493 13703340 YP_006780766.1 CDS O3K_20510 NC_018658.1 4212893 4213624 R COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; DNA polymerase III subunit epsilon complement(4212893..4213624) Escherichia coli O104:H4 str. 2011C-3493 13703342 YP_006780767.1 CDS rnhA NC_018658.1 4213689 4214156 D COG0328 Ribonuclease HI; ribonuclease H 4213689..4214156 Escherichia coli O104:H4 str. 2011C-3493 13703343 YP_006780768.1 CDS O3K_20520 NC_018658.1 4214153 4214875 R COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase complement(4214153..4214875) Escherichia coli O104:H4 str. 2011C-3493 13703344 YP_006780769.1 CDS O3K_20525 NC_018658.1 4214909 4215664 D COG0491 Zn-dependent hydrolases, including glyoxylases; hydroxyacylglutathione hydrolase 4214909..4215664 Escherichia coli O104:H4 str. 2011C-3493 13703345 YP_006780770.1 CDS mltD NC_018658.1 4215736 4217094 D COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); membrane-bound lytic murein transglycosylase D 4215736..4217094 Escherichia coli O104:H4 str. 2011C-3493 13703346 YP_006780771.1 CDS O3K_20535 NC_018658.1 4217142 4217912 R COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase complement(4217142..4217912) Escherichia coli O104:H4 str. 2011C-3493 13703347 YP_006780772.1 CDS O3K_20540 NC_018658.1 4217990 4218790 R COG3021 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4217990..4218790) Escherichia coli O104:H4 str. 2011C-3493 13703348 YP_006780773.1 CDS O3K_20545 NC_018658.1 4219031 4219945 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 4219031..4219945 Escherichia coli O104:H4 str. 2011C-3493 13703349 YP_006780774.1 CDS dkgB NC_018658.1 4219942 4220745 R COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-diketo-D-gluconate reductase B complement(4219942..4220745) Escherichia coli O104:H4 str. 2011C-3493 13703350 YP_006780775.1 CDS O3K_20555 NC_018658.1 4226644 4227216 R COG0241 Histidinol phosphatase and related phosphatases; D,D-heptose 1,7-bisphosphate phosphatase complement(4226644..4227216) Escherichia coli O104:H4 str. 2011C-3493 13703357 YP_006780776.1 CDS metN NC_018658.1 4227404 4228435 D COG1135 ABC-type metal ion transport system, ATPase component; DL-methionine transporter ATP-binding subunit 4227404..4228435 Escherichia coli O104:H4 str. 2011C-3493 13703358 YP_006780777.1 CDS O3K_20565 NC_018658.1 4228428 4229081 D COG2011 ABC-type metal ion transport system, permease component; DL-methionine transporter permease 4228428..4229081 Escherichia coli O104:H4 str. 2011C-3493 13703359 YP_006780778.1 CDS metQ NC_018658.1 4229121 4229936 D COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; DL-methionine transporter substrate-binding subunit 4229121..4229936 Escherichia coli O104:H4 str. 2011C-3493 13703360 YP_006780779.1 CDS rcsF NC_018658.1 4230054 4230458 D outer membrane lipoprotein 4230054..4230458 Escherichia coli O104:H4 str. 2011C-3493 13703361 YP_006780780.1 CDS O3K_20580 NC_018658.1 4230455 4231162 D COG1720 Uncharacterized conserved protein; hypothetical protein 4230455..4231162 Escherichia coli O104:H4 str. 2011C-3493 13703362 YP_006780781.1 CDS O3K_20585 NC_018658.1 4231274 4232992 D COG0442 Prolyl-tRNA synthetase; prolyl-tRNA synthetase 4231274..4232992 Escherichia coli O104:H4 str. 2011C-3493 13703363 YP_006780782.1 CDS O3K_20590 NC_018658.1 4233045 4233626 D COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 4233045..4233626 Escherichia coli O104:H4 str. 2011C-3493 13703364 YP_006780783.1 CDS O3K_20595 NC_018658.1 4233632 4233868 D hypothetical protein 4233632..4233868 Escherichia coli O104:H4 str. 2011C-3493 13703365 YP_006780784.1 CDS O3K_20600 NC_018658.1 4234072 4235052 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(4234072..4235052) Escherichia coli O104:H4 str. 2011C-3493 13703366 YP_006780785.1 CDS O3K_20605 NC_018658.1 4235302 4236012 R COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance; copper homeostasis and adhesion lipoprotein complement(4235302..4236012) Escherichia coli O104:H4 str. 2011C-3493 13703367 YP_006780786.1 CDS O3K_20610 NC_018658.1 4236026 4236448 R COG1186 Protein chain release factor B; hypothetical protein complement(4236026..4236448) Escherichia coli O104:H4 str. 2011C-3493 13703368 YP_006780787.1 CDS O3K_20615 NC_018658.1 4236445 4236990 R COG4681 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4236445..4236990) Escherichia coli O104:H4 str. 2011C-3493 13703369 YP_006780788.1 CDS O3K_20620 NC_018658.1 4237156 4237356 D hypothetical protein 4237156..4237356 Escherichia coli O104:H4 str. 2011C-3493 13703370 YP_006780789.1 CDS O3K_20625 NC_018658.1 4237343 4237603 D COG4568 Transcriptional antiterminator; Rho-binding antiterminator 4237343..4237603 Escherichia coli O104:H4 str. 2011C-3493 13703371 YP_006780790.1 CDS tilS NC_018658.1 4237652 4238950 R COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile)-lysidine synthetase complement(4237652..4238950) Escherichia coli O104:H4 str. 2011C-3493 13703372 YP_006780791.1 CDS O3K_20635 NC_018658.1 4239015 4239404 R COG0346 Lactoylglutathione lyase and related lyases; putative lyase complement(4239015..4239404) Escherichia coli O104:H4 str. 2011C-3493 13703373 YP_006780792.1 CDS O3K_20640 NC_018658.1 4239461 4241602 R COG1982 Arginine/lysine/ornithine decarboxylases; lysine decarboxylase LdcC complement(4239461..4241602) Escherichia coli O104:H4 str. 2011C-3493 13703374 YP_006780793.1 CDS O3K_20645 NC_018658.1 4241701 4242660 R COG0825 Acetyl-CoA carboxylase alpha subunit; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(4241701..4242660) Escherichia coli O104:H4 str. 2011C-3493 13703375 YP_006780794.1 CDS dnaE NC_018658.1 4242673 4246155 R COG0587 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha complement(4242673..4246155) Escherichia coli O104:H4 str. 2011C-3493 13703376 YP_006780795.1 CDS rnhB NC_018658.1 4246192 4246788 R COG0164 Ribonuclease HII; ribonuclease HII complement(4246192..4246788) Escherichia coli O104:H4 str. 2011C-3493 13703377 YP_006780796.1 CDS lpxB NC_018658.1 4246785 4247933 R COG0763 Lipid A disaccharide synthetase; lipid-A-disaccharide synthase complement(4246785..4247933) Escherichia coli O104:H4 str. 2011C-3493 13703378 YP_006780797.1 CDS O3K_20665 NC_018658.1 4247933 4248721 R COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; UDP-N-acetylglucosamine acyltransferase complement(4247933..4248721) Escherichia coli O104:H4 str. 2011C-3493 13703379 YP_006780798.1 CDS fabZ NC_018658.1 4248725 4249180 R COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; (3R)-hydroxymyristoyl-ACP dehydratase complement(4248725..4249180) Escherichia coli O104:H4 str. 2011C-3493 13703380 YP_006780799.1 CDS lpxD NC_018658.1 4249285 4250310 R COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(4249285..4250310) Escherichia coli O104:H4 str. 2011C-3493 13703381 YP_006780800.1 CDS O3K_20680 NC_018658.1 4250314 4250799 R COG2825 Outer membrane protein; periplasmic chaperone complement(4250314..4250799) Escherichia coli O104:H4 str. 2011C-3493 13703382 YP_006780801.1 CDS O3K_20685 NC_018658.1 4250921 4253353 R COG4775 Outer membrane protein/protective antigen OMA87; outer membrane protein assembly factor YaeT complement(4250921..4253353) Escherichia coli O104:H4 str. 2011C-3493 13703383 YP_006780802.1 CDS O3K_20690 NC_018658.1 4253383 4254735 R COG0750 Predicted membrane-associated Zn-dependent proteases 1; zinc metallopeptidase RseP complement(4253383..4254735) Escherichia coli O104:H4 str. 2011C-3493 13703384 YP_006780803.1 CDS cdsA NC_018658.1 4254747 4255604 R COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthase complement(4254747..4255604) Escherichia coli O104:H4 str. 2011C-3493 13703385 YP_006780804.1 CDS O3K_20700 NC_018658.1 4255617 4256375 R COG0020 Undecaprenyl pyrophosphate synthase; undecaprenyl pyrophosphate synthase complement(4255617..4256375) Escherichia coli O104:H4 str. 2011C-3493 13703386 YP_006780805.1 CDS O3K_20705 NC_018658.1 4256564 4257760 R COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(4256564..4257760) Escherichia coli O104:H4 str. 2011C-3493 13703387 YP_006780806.1 CDS frr NC_018658.1 4257852 4258409 R COG0233 Ribosome recycling factor; ribosome recycling factor complement(4257852..4258409) Escherichia coli O104:H4 str. 2011C-3493 13703388 YP_006780807.1 CDS pyrH NC_018658.1 4258701 4259426 R COG0528 Uridylate kinase; uridylate kinase complement(4258701..4259426) Escherichia coli O104:H4 str. 2011C-3493 13703389 YP_006780808.1 CDS tsf NC_018658.1 4259573 4260424 R COG0264 Translation elongation factor Ts; elongation factor Ts complement(4259573..4260424) Escherichia coli O104:H4 str. 2011C-3493 13703390 YP_006780809.1 CDS rpsB NC_018658.1 4260682 4261407 R COG0052 Ribosomal protein S2; 30S ribosomal protein S2 complement(4260682..4261407) Escherichia coli O104:H4 str. 2011C-3493 13703391 YP_006780810.1 CDS O3K_20730 NC_018658.1 4261775 4262569 D COG0024 Methionine aminopeptidase; methionine aminopeptidase 4261775..4262569 Escherichia coli O104:H4 str. 2011C-3493 13703392 YP_006780811.1 CDS O3K_20735 NC_018658.1 4262631 4265303 D COG2844 UTP:GlnB (protein PII) uridylyltransferase; PII uridylyl-transferase 4262631..4265303 Escherichia coli O104:H4 str. 2011C-3493 13703393 YP_006780812.1 CDS dapD NC_018658.1 4265334 4266158 D COG2171 Tetrahydrodipicolinate N-succinyltransferase; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 4265334..4266158 Escherichia coli O104:H4 str. 2011C-3493 13703394 YP_006780813.1 CDS O3K_20745 NC_018658.1 4266473 4266859 D hypothetical protein 4266473..4266859 Escherichia coli O104:H4 str. 2011C-3493 13703395 YP_006780814.1 CDS O3K_20750 NC_018658.1 4266948 4268105 R COG3835 Sugar diacid utilization regulator; carbohydrate diacid transcriptional activator CdaR complement(4266948..4268105) Escherichia coli O104:H4 str. 2011C-3493 13703396 YP_006780815.1 CDS O3K_20755 NC_018658.1 4268260 4269684 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease complement(4268260..4269684) Escherichia coli O104:H4 str. 2011C-3493 13703397 YP_006780816.1 CDS dgt NC_018658.1 4269814 4271331 R COG0232 dGTP triphosphohydrolase; deoxyguanosinetriphosphate triphosphohydrolase complement(4269814..4271331) Escherichia coli O104:H4 str. 2011C-3493 13703398 YP_006780817.1 CDS O3K_20765 NC_018658.1 4271415 4272113 D COG0775 Nucleoside phosphorylase; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 4271415..4272113 Escherichia coli O104:H4 str. 2011C-3493 13703399 YP_006780818.1 CDS O3K_20770 NC_018658.1 4272106 4272906 D COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; vitamin B12-transporter protein BtuF 4272106..4272906 Escherichia coli O104:H4 str. 2011C-3493 13703400 YP_006780819.1 CDS O3K_20775 NC_018658.1 4272944 4273567 D COG2860 Predicted membrane protein; hypothetical protein 4272944..4273567 Escherichia coli O104:H4 str. 2011C-3493 13703401 YP_006780820.1 CDS O3K_20780 NC_018658.1 4273614 4273958 R COG0316 Uncharacterized conserved protein; iron-sulfur cluster insertion protein ErpA complement(4273614..4273958) Escherichia coli O104:H4 str. 2011C-3493 13703402 YP_006780821.1 CDS O3K_20785 NC_018658.1 4274040 4275461 R COG0038 Chloride channel protein EriC; chloride channel protein complement(4274040..4275461) Escherichia coli O104:H4 str. 2011C-3493 13703403 YP_006780822.1 CDS O3K_20790 NC_018658.1 4275686 4276966 D COG0001 Glutamate-1-semialdehyde aminotransferase; glutamate-1-semialdehyde aminotransferase 4275686..4276966 Escherichia coli O104:H4 str. 2011C-3493 13703404 YP_006780823.1 CDS O3K_20795 NC_018658.1 4277001 4278983 R COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-hydroxamate transporter permease subunit complement(4277001..4278983) Escherichia coli O104:H4 str. 2011C-3493 13703405 YP_006780824.1 CDS O3K_20800 NC_018658.1 4278980 4279870 R COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; iron-hydroxamate transporter substrate-binding subunit complement(4278980..4279870) Escherichia coli O104:H4 str. 2011C-3493 13703406 YP_006780825.1 CDS O3K_20805 NC_018658.1 4279870 4280667 R COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-hydroxamate transporter ATP-binding subunit complement(4279870..4280667) Escherichia coli O104:H4 str. 2011C-3493 13703407 YP_006780826.1 CDS O3K_20810 NC_018658.1 4280718 4282961 R COG1629 Outer membrane receptor proteins, mostly Fe transport; ferrichrome outer membrane transporter complement(4280718..4282961) Escherichia coli O104:H4 str. 2011C-3493 13703408 YP_006780827.1 CDS mrcB NC_018658.1 4283181 4285715 R COG0744 Membrane carboxypeptidase (penicillin-binding protein); bifunctional glycosyl transferase/transpeptidase complement(4283181..4285715) Escherichia coli O104:H4 str. 2011C-3493 13703409 YP_006780828.1 CDS O3K_20820 NC_018658.1 4285702 4285872 R hypothetical protein complement(4285702..4285872) Escherichia coli O104:H4 str. 2011C-3493 13703410 YP_006780829.1 CDS O3K_20825 NC_018658.1 4285911 4288340 R COG1643 HrpA-like helicases; ATP-dependent RNA helicase HrpB complement(4285911..4288340) Escherichia coli O104:H4 str. 2011C-3493 13703411 YP_006780830.1 CDS O3K_20830 NC_018658.1 4288414 4288944 D COG1514 2'-5' RNA ligase; 2'-5' RNA ligase 4288414..4288944 Escherichia coli O104:H4 str. 2011C-3493 13703412 YP_006780831.1 CDS O3K_20835 NC_018658.1 4288959 4289663 D COG1489 DNA-binding protein, stimulates sugar fermentation; putative DNA-binding transcriptional regulator 4288959..4289663 Escherichia coli O104:H4 str. 2011C-3493 13703413 YP_006780832.1 CDS dksA NC_018658.1 4289841 4290296 D COG1734 DnaK suppressor protein; RNA polymerase-binding transcription factor 4289841..4290296 Escherichia coli O104:H4 str. 2011C-3493 13703414 YP_006780833.1 CDS O3K_20845 NC_018658.1 4290333 4291259 D COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-Q tRNA(Asp) synthetase 4290333..4291259 Escherichia coli O104:H4 str. 2011C-3493 13703415 YP_006780834.1 CDS pcnB NC_018658.1 4291298 4292716 D COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; poly(A) polymerase I 4291298..4292716 Escherichia coli O104:H4 str. 2011C-3493 13703416 YP_006780835.1 CDS O3K_20855 NC_018658.1 4292713 4293192 D COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 4292713..4293192 Escherichia coli O104:H4 str. 2011C-3493 13703417 YP_006780836.1 CDS O3K_20860 NC_018658.1 4293562 4294146 D COG3539 P pilus assembly protein, pilin FimA; putative fimbrial-like protein 4293562..4294146 Escherichia coli O104:H4 str. 2011C-3493 13703418 YP_006780837.1 CDS O3K_20865 NC_018658.1 4294251 4294991 D COG3121 P pilus assembly protein, chaperone PapD; putative chaperone protein EcpD 4294251..4294991 Escherichia coli O104:H4 str. 2011C-3493 13703419 YP_006780838.1 CDS O3K_20870 NC_018658.1 4295026 4297626 D COG3188 P pilus assembly protein, porin PapC; putative fimbrial outer membrane usher protein 4295026..4297626 Escherichia coli O104:H4 str. 2011C-3493 13703420 YP_006780839.1 CDS O3K_20875 NC_018658.1 4297643 4298212 D putative fimbrial protein 4297643..4298212 Escherichia coli O104:H4 str. 2011C-3493 13703421 YP_006780840.1 CDS O3K_20880 NC_018658.1 4298227 4298829 D putative fimbrial protein StaE 4298227..4298829 Escherichia coli O104:H4 str. 2011C-3493 13703422 YP_006780841.1 CDS O3K_20885 NC_018658.1 4298856 4299452 D putative fimbrial protein StaF 4298856..4299452 Escherichia coli O104:H4 str. 2011C-3493 13703423 YP_006780842.1 CDS O3K_20890 NC_018658.1 4299505 4300779 D putative fimbrial-like adhesin protein 4299505..4300779 Escherichia coli O104:H4 str. 2011C-3493 13703424 YP_006780843.1 CDS panB NC_018658.1 4300892 4301686 D COG0413 Ketopantoate hydroxymethyltransferase; 3-methyl-2-oxobutanoate hydroxymethyltransferase 4300892..4301686 Escherichia coli O104:H4 str. 2011C-3493 13703425 YP_006780844.1 CDS panC NC_018658.1 4301698 4302549 D COG0414 Panthothenate synthetase; pantoate--beta-alanine ligase 4301698..4302549 Escherichia coli O104:H4 str. 2011C-3493 13703426 YP_006780845.1 CDS O3K_20905 NC_018658.1 4302623 4303525 R transposase complement(4302623..4303525) Escherichia coli O104:H4 str. 2011C-3493 13703427 YP_006780846.1 CDS O3K_20910 NC_018658.1 4303799 4304179 D COG0853 Aspartate 1-decarboxylase; aspartate alpha-decarboxylase 4303799..4304179 Escherichia coli O104:H4 str. 2011C-3493 13703428 YP_006780847.1 CDS O3K_20915 NC_018658.1 4304183 4305412 R COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase complement(4304183..4305412) Escherichia coli O104:H4 str. 2011C-3493 13703429 YP_006780848.1 CDS O3K_20920 NC_018658.1 4305476 4305916 R COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system transporter subunit IIA complement(4305476..4305916) Escherichia coli O104:H4 str. 2011C-3493 13703430 YP_006780849.1 CDS O3K_20925 NC_018658.1 4306021 4306791 R COG0842 ABC-type multidrug transport system, permease component; inner membrane transport permease complement(4306021..4306791) Escherichia coli O104:H4 str. 2011C-3493 13703431 YP_006780850.1 CDS O3K_20930 NC_018658.1 4306788 4307714 R COG1131 ABC-type multidrug transport system, ATPase component; putative transporter subunit complement(4306788..4307714) Escherichia coli O104:H4 str. 2011C-3493 13703432 YP_006780851.1 CDS O3K_20935 NC_018658.1 4307823 4308485 D COG0288 Carbonic anhydrase; carbonic anhydrase 4307823..4308485 Escherichia coli O104:H4 str. 2011C-3493 13703433 YP_006780852.1 CDS O3K_20940 NC_018658.1 4308526 4309062 R COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase complement(4308526..4309062) Escherichia coli O104:H4 str. 2011C-3493 13703434 YP_006780853.1 CDS O3K_20945 NC_018658.1 4309268 4311658 D COG4993 Glucose dehydrogenase; glucose dehydrogenase 4309268..4311658 Escherichia coli O104:H4 str. 2011C-3493 13703435 YP_006780854.1 CDS O3K_20950 NC_018658.1 4311705 4313255 R COG2132 Putative multicopper oxidases; multicopper oxidase complement(4311705..4313255) Escherichia coli O104:H4 str. 2011C-3493 13703436 YP_006780855.1 CDS O3K_20955 NC_018658.1 4313421 4313768 D hypothetical protein 4313421..4313768 Escherichia coli O104:H4 str. 2011C-3493 13703437 YP_006780856.1 CDS O3K_20960 NC_018658.1 4313874 4314740 D COG0421 Spermidine synthase; spermidine synthase 4313874..4314740 Escherichia coli O104:H4 str. 2011C-3493 13703438 YP_006780857.1 CDS O3K_20965 NC_018658.1 4314756 4315550 D COG1586 S-adenosylmethionine decarboxylase; S-adenosylmethionine decarboxylase 4314756..4315550 Escherichia coli O104:H4 str. 2011C-3493 13703439 YP_006780858.1 CDS O3K_20970 NC_018658.1 4315588 4315950 R COG3112 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4315588..4315950) Escherichia coli O104:H4 str. 2011C-3493 13703440 YP_006780859.1 CDS O3K_20975 NC_018658.1 4316126 4318723 R COG1049 Aconitase B; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase complement(4316126..4318723) Escherichia coli O104:H4 str. 2011C-3493 13703441 YP_006780860.1 CDS O3K_20980 NC_018658.1 4319078 4320835 D hypothetical protein 4319078..4320835 Escherichia coli O104:H4 str. 2011C-3493 13703442 YP_006780861.1 CDS O3K_20985 NC_018658.1 4320906 4322330 R COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; dihydrolipoamide dehydrogenase complement(4320906..4322330) Escherichia coli O104:H4 str. 2011C-3493 13703443 YP_006780862.1 CDS aceF NC_018658.1 4322655 4324547 R COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; pyruvate dehydrogenase dihydrolipoyltransacetylase complement(4322655..4324547) Escherichia coli O104:H4 str. 2011C-3493 13703444 YP_006780863.1 CDS aceE NC_018658.1 4324562 4327225 R COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component; pyruvate dehydrogenase subunit E1 complement(4324562..4327225) Escherichia coli O104:H4 str. 2011C-3493 13703445 YP_006780864.1 CDS pdhR NC_018658.1 4327386 4328150 R COG2186 Transcriptional regulators; transcriptional regulator PdhR complement(4327386..4328150) Escherichia coli O104:H4 str. 2011C-3493 13703446 YP_006780865.1 CDS O3K_21005 NC_018658.1 4328694 4330064 D COG1113 Gamma-aminobutyrate permease and related permeases; aromatic amino acid transporter 4328694..4330064 Escherichia coli O104:H4 str. 2011C-3493 13703447 YP_006780866.1 CDS O3K_21010 NC_018658.1 4330107 4330961 R COG1270 Cobalamin biosynthesis protein CobD/CbiB; regulatory protein AmpE complement(4330107..4330961) Escherichia coli O104:H4 str. 2011C-3493 13703448 YP_006780867.1 CDS O3K_21015 NC_018658.1 4330958 4331509 R COG3023 Negative regulator of beta-lactamase expression; N-acetyl-anhydromuranmyl-L-alanine amidase complement(4330958..4331509) Escherichia coli O104:H4 str. 2011C-3493 13703449 YP_006780868.1 CDS O3K_21020 NC_018658.1 4331597 4332490 D COG0157 Nicotinate-nucleotide pyrophosphorylase; quinolinate phosphoribosyltransferase 4331597..4332490 Escherichia coli O104:H4 str. 2011C-3493 13703450 YP_006780869.1 CDS O3K_21025 NC_018658.1 4332693 4333133 D COG4969 Tfp pilus assembly protein, major pilin PilA; putative major pilin subunit 4332693..4333133 Escherichia coli O104:H4 str. 2011C-3493 13703451 YP_006780870.1 CDS O3K_21030 NC_018658.1 4333143 4334528 D COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; hypothetical protein 4333143..4334528 Escherichia coli O104:H4 str. 2011C-3493 13703452 YP_006780871.1 CDS O3K_21035 NC_018658.1 4334518 4335720 D COG1459 Type II secretory pathway, component PulF; type IV pilin biogenesis protein 4334518..4335720 Escherichia coli O104:H4 str. 2011C-3493 13703453 YP_006780872.1 CDS O3K_21040 NC_018658.1 4335755 4336798 R COG0516 IMP dehydrogenase/GMP reductase; guanosine 5'-monophosphate oxidoreductase complement(4335755..4336798) Escherichia coli O104:H4 str. 2011C-3493 13703454 YP_006780873.1 CDS coaE NC_018658.1 4337023 4337643 D COG0237 Dephospho-CoA kinase; dephospho-CoA kinase 4337023..4337643 Escherichia coli O104:H4 str. 2011C-3493 13703455 YP_006780874.1 CDS O3K_21050 NC_018658.1 4337643 4338386 D COG4582 Uncharacterized protein conserved in bacteria; hypothetical protein 4337643..4338386 Escherichia coli O104:H4 str. 2011C-3493 13703456 YP_006780875.1 CDS O3K_21055 NC_018658.1 4338396 4338593 D COG3024 Uncharacterized protein conserved in bacteria; DNA gyrase inhibitor 4338396..4338593 Escherichia coli O104:H4 str. 2011C-3493 13703457 YP_006780876.1 CDS O3K_21060 NC_018658.1 4338693 4339082 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; nucleoside triphosphate pyrophosphohydrolase complement(4338693..4339082) Escherichia coli O104:H4 str. 2011C-3493 13703458 YP_006780877.1 CDS O3K_21065 NC_018658.1 4339142 4341847 R COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); preprotein translocase subunit SecA complement(4339142..4341847) Escherichia coli O104:H4 str. 2011C-3493 13703459 YP_006780878.1 CDS O3K_21070 NC_018658.1 4341909 4342421 R SecA regulator SecM complement(4341909..4342421) Escherichia coli O104:H4 str. 2011C-3493 13703460 YP_006780879.1 CDS lpxC NC_018658.1 4342652 4343569 R COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(4342652..4343569) Escherichia coli O104:H4 str. 2011C-3493 13703461 YP_006780880.1 CDS O3K_21080 NC_018658.1 4343670 4344821 R COG0206 Cell division GTPase; cell division protein FtsZ complement(4343670..4344821) Escherichia coli O104:H4 str. 2011C-3493 13703462 YP_006780881.1 CDS ftsA NC_018658.1 4344882 4346144 R COG0849 Actin-like ATPase involved in cell division; cell division protein FtsA complement(4344882..4346144) Escherichia coli O104:H4 str. 2011C-3493 13703463 YP_006780882.1 CDS O3K_21090 NC_018658.1 4346141 4346971 R COG1589 Cell division septal protein; cell division protein FtsQ complement(4346141..4346971) Escherichia coli O104:H4 str. 2011C-3493 13703464 YP_006780883.1 CDS ddl NC_018658.1 4346973 4347893 R COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanine--D-alanine ligase complement(4346973..4347893) Escherichia coli O104:H4 str. 2011C-3493 13703465 YP_006780884.1 CDS murC NC_018658.1 4347886 4349361 R COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate--L-alanine ligase complement(4347886..4349361) Escherichia coli O104:H4 str. 2011C-3493 13703466 YP_006780885.1 CDS murG NC_018658.1 4349415 4350482 R COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase complement(4349415..4350482) Escherichia coli O104:H4 str. 2011C-3493 13703467 YP_006780886.1 CDS O3K_21110 NC_018658.1 4350479 4351723 R COG0772 Bacterial cell division membrane protein; cell division protein FtsW complement(4350479..4351723) Escherichia coli O104:H4 str. 2011C-3493 13703468 YP_006780887.1 CDS murD NC_018658.1 4351723 4353039 R COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(4351723..4353039) Escherichia coli O104:H4 str. 2011C-3493 13703469 YP_006780888.1 CDS mraY NC_018658.1 4353042 4354124 R COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(4353042..4354124) Escherichia coli O104:H4 str. 2011C-3493 13703470 YP_006780889.1 CDS murF NC_018658.1 4354118 4355476 R COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(4354118..4355476) Escherichia coli O104:H4 str. 2011C-3493 13703471 YP_006780890.1 CDS murE NC_018658.1 4355473 4356960 R COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(4355473..4356960) Escherichia coli O104:H4 str. 2011C-3493 13703472 YP_006780891.1 CDS O3K_21135 NC_018658.1 4356947 4358713 R COG0768 Cell division protein FtsI/penicillin-binding protein 2; peptidoglycan synthase FtsI complement(4356947..4358713) Escherichia coli O104:H4 str. 2011C-3493 13703473 YP_006780892.1 CDS O3K_21140 NC_018658.1 4358729 4359094 R COG3116 Cell division protein; cell division protein FtsL complement(4358729..4359094) Escherichia coli O104:H4 str. 2011C-3493 13703474 YP_006780893.1 CDS O3K_21145 NC_018658.1 4359091 4360032 R COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; 16S rRNA m(4)C1402 methyltransferase complement(4359091..4360032) Escherichia coli O104:H4 str. 2011C-3493 13703475 YP_006780894.1 CDS O3K_21150 NC_018658.1 4360034 4360492 R COG2001 Uncharacterized protein conserved in bacteria; cell division protein MraZ complement(4360034..4360492) Escherichia coli O104:H4 str. 2011C-3493 13703476 YP_006780895.1 CDS O3K_21155 NC_018658.1 4361094 4362098 R COG1609 Transcriptional regulators; DNA-binding transcriptional regulator FruR complement(4361094..4362098) Escherichia coli O104:H4 str. 2011C-3493 13703477 YP_006780896.1 CDS ilvH NC_018658.1 4362278 4362769 R COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase 3 regulatory subunit complement(4362278..4362769) Escherichia coli O104:H4 str. 2011C-3493 13703478 YP_006780897.1 CDS O3K_21165 NC_018658.1 4362772 4364496 R COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase 3 catalytic subunit complement(4362772..4364496) Escherichia coli O104:H4 str. 2011C-3493 13703479 YP_006780898.1 CDS leuO NC_018658.1 4364814 4365758 R COG0583 Transcriptional regulator; leucine transcriptional activator complement(4364814..4365758) Escherichia coli O104:H4 str. 2011C-3493 13703480 YP_006780899.1 CDS O3K_21175 NC_018658.1 4366418 4366504 D leu operon leader peptide 4366418..4366504 Escherichia coli O104:H4 str. 2011C-3493 13703481 YP_006780900.1 CDS O3K_21180 NC_018658.1 4366597 4368168 D COG0119 Isopropylmalate/homocitrate/citramalate synthases; 2-isopropylmalate synthase 4366597..4368168 Escherichia coli O104:H4 str. 2011C-3493 13703482 YP_006780901.1 CDS O3K_21185 NC_018658.1 4368168 4369259 D COG0473 Isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 4368168..4369259 Escherichia coli O104:H4 str. 2011C-3493 13703483 YP_006780902.1 CDS O3K_21190 NC_018658.1 4369262 4370662 D COG0065 3-isopropylmalate dehydratase large subunit; isopropylmalate isomerase large subunit 4369262..4370662 Escherichia coli O104:H4 str. 2011C-3493 13703484 YP_006780903.1 CDS leuD NC_018658.1 4370673 4371278 D COG0066 3-isopropylmalate dehydratase small subunit; isopropylmalate isomerase small subunit 4370673..4371278 Escherichia coli O104:H4 str. 2011C-3493 13703485 YP_006780904.1 CDS O3K_21200 NC_018658.1 4371327 4372505 R COG0477 Permeases of the major facilitator superfamily; broad specificity sugar efflux system SetA complement(4371327..4372505) Escherichia coli O104:H4 str. 2011C-3493 13703486 YP_006780905.1 CDS O3K_21205 NC_018658.1 4372607 4372738 R hypothetical protein complement(4372607..4372738) Escherichia coli O104:H4 str. 2011C-3493 13703487 YP_006780906.1 CDS O3K_21210 NC_018658.1 4372827 4374482 D COG4533 ABC-type uncharacterized transport system, periplasmic component; transcriptional regulator SgrR 4372827..4374482 Escherichia coli O104:H4 str. 2011C-3493 13703488 YP_006780907.1 CDS tbpA NC_018658.1 4374646 4375629 D COG4143 ABC-type thiamine transport system, periplasmic component; thiamine transporter substrate binding subunit 4374646..4375629 Escherichia coli O104:H4 str. 2011C-3493 13703489 YP_006780908.1 CDS thiP NC_018658.1 4375605 4377215 D COG0555 ABC-type sulfate transport system, permease component; thiamine transporter membrane protein 4375605..4377215 Escherichia coli O104:H4 str. 2011C-3493 13703490 YP_006780909.1 CDS thiQ NC_018658.1 4377199 4377897 D COG3840 ABC-type thiamine transport system, ATPase component; thiamine transporter ATP-binding subunit 4377199..4377897 Escherichia coli O104:H4 str. 2011C-3493 13703491 YP_006780910.1 CDS O3K_21230 NC_018658.1 4378011 4378775 R COG0586 Uncharacterized membrane-associated protein; hypothetical protein complement(4378011..4378775) Escherichia coli O104:H4 str. 2011C-3493 13703492 YP_006780911.1 CDS O3K_21235 NC_018658.1 4378861 4379739 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator AraC complement(4378861..4379739) Escherichia coli O104:H4 str. 2011C-3493 13703493 YP_006780912.1 CDS O3K_21240 NC_018658.1 4380078 4381778 D COG1069 Ribulose kinase; ribulokinase 4380078..4381778 Escherichia coli O104:H4 str. 2011C-3493 13703494 YP_006780913.1 CDS O3K_21245 NC_018658.1 4381789 4383291 D COG2160 L-arabinose isomerase; L-arabinose isomerase 4381789..4383291 Escherichia coli O104:H4 str. 2011C-3493 13703495 YP_006780914.1 CDS araD NC_018658.1 4383460 4384155 D COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase 4383460..4384155 Escherichia coli O104:H4 str. 2011C-3493 13703496 YP_006780915.1 CDS O3K_21255 NC_018658.1 4384230 4386581 D COG0417 DNA polymerase elongation subunit (family B); DNA polymerase II 4384230..4386581 Escherichia coli O104:H4 str. 2011C-3493 13703497 YP_006780916.1 CDS O3K_21260 NC_018658.1 4386746 4389652 D COG0553 Superfamily II DNA/RNA helicases, SNF2 family; ATP-dependent helicase HepA 4386746..4389652 Escherichia coli O104:H4 str. 2011C-3493 13703498 YP_006780917.1 CDS O3K_21265 NC_018658.1 4389664 4390323 D COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA/tRNA pseudouridine synthase A 4389664..4390323 Escherichia coli O104:H4 str. 2011C-3493 13703499 YP_006780918.1 CDS djlA NC_018658.1 4390440 4391255 R COG1076 DnaJ-domain-containing proteins 1; Dna-J like membrane chaperone protein complement(4390440..4391255) Escherichia coli O104:H4 str. 2011C-3493 13703500 YP_006780919.1 CDS O3K_21275 NC_018658.1 4391510 4393864 D COG1452 Organic solvent tolerance protein OstA; LPS assembly outer membrane complex protein LptD 4391510..4393864 Escherichia coli O104:H4 str. 2011C-3493 13703501 YP_006780920.1 CDS O3K_21280 NC_018658.1 4393917 4395203 D COG0760 Parvulin-like peptidyl-prolyl isomerase; peptidyl-prolyl cis-trans isomerase SurA 4393917..4395203 Escherichia coli O104:H4 str. 2011C-3493 13703502 YP_006780921.1 CDS pdxA NC_018658.1 4395203 4396192 D COG1995 Pyridoxal phosphate biosynthesis protein; 4-hydroxythreonine-4-phosphate dehydrogenase 4395203..4396192 Escherichia coli O104:H4 str. 2011C-3493 13703503 YP_006780922.1 CDS ksgA NC_018658.1 4396189 4397010 D COG0030 Dimethyladenosine transferase (rRNA methylation); KsgA/Dim1 family 16S ribosomal RNA methyltransferase 4396189..4397010 Escherichia coli O104:H4 str. 2011C-3493 13703504 YP_006780923.1 CDS apaG NC_018658.1 4397013 4397390 D COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport; CO2+/MG2+ efflux protein ApaG 4397013..4397390 Escherichia coli O104:H4 str. 2011C-3493 13703505 YP_006780924.1 CDS apaH NC_018658.1 4397397 4398239 D COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase 4397397..4398239 Escherichia coli O104:H4 str. 2011C-3493 13703506 YP_006780925.1 CDS folA NC_018658.1 4398317 4398796 R COG0262 Dihydrofolate reductase; dihydrofolate reductase complement(4398317..4398796) Escherichia coli O104:H4 str. 2011C-3493 13703507 YP_006780926.1 CDS O3K_21310 NC_018658.1 4398988 4400850 R COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefC complement(4398988..4400850) Escherichia coli O104:H4 str. 2011C-3493 13703508 YP_006780927.1 CDS O3K_21315 NC_018658.1 4400843 4401373 R COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); glutathione-regulated potassium-efflux system ancillary protein KefF complement(4400843..4401373) Escherichia coli O104:H4 str. 2011C-3493 13703509 YP_006780928.1 CDS O3K_21320 NC_018658.1 4401481 4402812 R COG0477 Permeases of the major facilitator superfamily; transporter complement(4401481..4402812) Escherichia coli O104:H4 str. 2011C-3493 13703510 YP_006780929.1 CDS O3K_21325 NC_018658.1 4402871 4403158 R COG2440 Ferredoxin-like protein; ferredoxin-like protein FixX complement(4402871..4403158) Escherichia coli O104:H4 str. 2011C-3493 13703511 YP_006780930.1 CDS O3K_21330 NC_018658.1 4403155 4404441 R COG0644 Dehydrogenases (flavoproteins); putative oxidoreductase FixC complement(4403155..4404441) Escherichia coli O104:H4 str. 2011C-3493 13703512 YP_006780931.1 CDS fixB NC_018658.1 4404492 4405433 R COG2025 Electron transfer flavoprotein, alpha subunit; putative electron transfer flavoprotein FixB complement(4404492..4405433) Escherichia coli O104:H4 str. 2011C-3493 13703513 YP_006780932.1 CDS O3K_21340 NC_018658.1 4405448 4406218 R COG2086 Electron transfer flavoprotein, beta subunit; putative electron transfer flavoprotein FixA complement(4405448..4406218) Escherichia coli O104:H4 str. 2011C-3493 13703514 YP_006780933.1 CDS O3K_21345 NC_018658.1 4406692 4408206 D COG1292 Choline-glycine betaine transporter; L-carnitine/gamma-butyrobetaine antiporter 4406692..4408206 Escherichia coli O104:H4 str. 2011C-3493 13703515 YP_006780934.1 CDS O3K_21350 NC_018658.1 4408237 4409379 D COG1960 Acyl-CoA dehydrogenases; crotonobetainyl-CoA dehydrogenase 4408237..4409379 Escherichia coli O104:H4 str. 2011C-3493 13703516 YP_006780935.1 CDS O3K_21355 NC_018658.1 4409508 4410725 D COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; crotonobetainyl-CoA:carnitine CoA-transferase 4409508..4410725 Escherichia coli O104:H4 str. 2011C-3493 13703517 YP_006780936.1 CDS caiC NC_018658.1 4410799 4412352 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; putative crotonobetaine/carnitine-CoA ligase 4410799..4412352 Escherichia coli O104:H4 str. 2011C-3493 13703518 YP_006780937.1 CDS O3K_21365 NC_018658.1 4412461 4413246 D COG1024 Enoyl-CoA hydratase/carnithine racemase; carnitinyl-CoA dehydratase 4412461..4413246 Escherichia coli O104:H4 str. 2011C-3493 13703519 YP_006780938.1 CDS O3K_21370 NC_018658.1 4413252 4413842 D COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; carnitine operon protein CaiE 4413252..4413842 Escherichia coli O104:H4 str. 2011C-3493 13703520 YP_006780939.1 CDS O3K_21375 NC_018658.1 4413928 4414323 R DNA-binding transcriptional activator CaiF complement(4413928..4414323) Escherichia coli O104:H4 str. 2011C-3493 13703521 YP_006780940.1 CDS carB NC_018658.1 4414584 4417805 R COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); carbamoyl phosphate synthase large subunit complement(4414584..4417805) Escherichia coli O104:H4 str. 2011C-3493 13703522 YP_006780941.1 CDS O3K_21385 NC_018658.1 4417823 4418971 R COG0505 Carbamoylphosphate synthase small subunit; carbamoyl phosphate synthase small subunit complement(4417823..4418971) Escherichia coli O104:H4 str. 2011C-3493 13703523 YP_006780942.1 CDS O3K_21390 NC_018658.1 4419089 4419184 D hypothetical protein 4419089..4419184 Escherichia coli O104:H4 str. 2011C-3493 13703524 YP_006780943.1 CDS O3K_21395 NC_018658.1 4419427 4420248 R COG0289 Dihydrodipicolinate reductase; dihydrodipicolinate reductase complement(4419427..4420248) Escherichia coli O104:H4 str. 2011C-3493 13703525 YP_006780944.1 CDS O3K_21400 NC_018658.1 4420415 4421329 R COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase RihC complement(4420415..4421329) Escherichia coli O104:H4 str. 2011C-3493 13703526 YP_006780945.1 CDS ispH NC_018658.1 4421395 4422345 R COG0761 Penicillin tolerance protein; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(4421395..4422345) Escherichia coli O104:H4 str. 2011C-3493 13703527 YP_006780946.1 CDS O3K_21410 NC_018658.1 4422347 4422796 R COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; FKBP-type peptidyl-prolyl cis-trans isomerase complement(4422347..4422796) Escherichia coli O104:H4 str. 2011C-3493 13703528 YP_006780947.1 CDS lspA NC_018658.1 4422884 4423378 R COG0597 Lipoprotein signal peptidase; lipoprotein signal peptidase complement(4422884..4423378) Escherichia coli O104:H4 str. 2011C-3493 13703529 YP_006780948.1 CDS ileS NC_018658.1 4423378 4426194 R COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase complement(4423378..4426194) Escherichia coli O104:H4 str. 2011C-3493 13703530 YP_006780949.1 CDS O3K_21425 NC_018658.1 4426237 4427178 R COG0196 FAD synthase; bifunctional riboflavin kinase/FMN adenylyltransferase complement(4426237..4427178) Escherichia coli O104:H4 str. 2011C-3493 13703531 YP_006780950.1 CDS O3K_21430 NC_018658.1 4427186 4427404 R hypothetical protein complement(4427186..4427404) Escherichia coli O104:H4 str. 2011C-3493 13703532 YP_006780951.1 CDS rpsT NC_018658.1 4427507 4427770 D COG0268 Ribosomal protein S20; 30S ribosomal protein S20 4427507..4427770 Escherichia coli O104:H4 str. 2011C-3493 13703533 YP_006780952.1 CDS O3K_21440 NC_018658.1 4428553 4429674 D COG1357 Uncharacterized low-complexity proteins; T3SS effector EspX 4428553..4429674 Escherichia coli O104:H4 str. 2011C-3493 13703534 YP_006780953.1 CDS O3K_21445 NC_018658.1 4430107 4431252 D COG3188 P pilus assembly protein, porin PapC; hypothetical protein 4430107..4431252 Escherichia coli O104:H4 str. 2011C-3493 13703535 YP_006780954.1 CDS O3K_21450 NC_018658.1 4431265 4432224 D hypothetical protein 4431265..4432224 Escherichia coli O104:H4 str. 2011C-3493 13703536 YP_006780955.1 CDS nhaR NC_018658.1 4432263 4433168 R COG0583 Transcriptional regulator; transcriptional activator NhaR complement(4432263..4433168) Escherichia coli O104:H4 str. 2011C-3493 13703537 YP_006780956.1 CDS nhaA NC_018658.1 4433228 4434394 R COG3004 Na+/H+ antiporter; pH-dependent sodium/proton antiporter complement(4433228..4434394) Escherichia coli O104:H4 str. 2011C-3493 13703538 YP_006780957.1 CDS O3K_21465 NC_018658.1 4434923 4435132 D regulatory protein MokC for HokC 4434923..4435132 Escherichia coli O104:H4 str. 2011C-3493 13703539 YP_006780958.1 CDS O3K_21470 NC_018658.1 4435236 4436366 R COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; chaperone protein DnaJ complement(4435236..4436366) Escherichia coli O104:H4 str. 2011C-3493 13703540 YP_006780959.1 CDS dnaK NC_018658.1 4436455 4438371 R COG0443 Molecular chaperone; molecular chaperone DnaK complement(4436455..4438371) Escherichia coli O104:H4 str. 2011C-3493 13703541 YP_006780960.1 CDS O3K_21480 NC_018658.1 4438748 4439152 D hypothetical protein 4438748..4439152 Escherichia coli O104:H4 str. 2011C-3493 13703542 YP_006780961.1 CDS O3K_21485 NC_018658.1 4439178 4439891 D COG4735 Uncharacterized protein conserved in bacteria; hypothetical protein 4439178..4439891 Escherichia coli O104:H4 str. 2011C-3493 13703543 YP_006780962.1 CDS O3K_21490 NC_018658.1 4440040 4440606 D COG1584 Predicted membrane protein; hypothetical protein 4440040..4440606 Escherichia coli O104:H4 str. 2011C-3493 13703544 YP_006780963.1 CDS mogA NC_018658.1 4440641 4441228 R COG0521 Molybdopterin biosynthesis enzymes; molybdenum cofactor biosynthesis protein MogA complement(4440641..4441228) Escherichia coli O104:H4 str. 2011C-3493 13703545 YP_006780964.1 CDS O3K_21500 NC_018658.1 4441343 4442296 R COG0176 Transaldolase; transaldolase B complement(4441343..4442296) Escherichia coli O104:H4 str. 2011C-3493 13703546 YP_006780965.1 CDS O3K_21505 NC_018658.1 4442575 4444005 D COG1115 Na+/alanine symporter; transporter 4442575..4444005 Escherichia coli O104:H4 str. 2011C-3493 13703547 YP_006780966.1 CDS O3K_21510 NC_018658.1 4444075 4444851 D COG3022 Uncharacterized protein conserved in bacteria; hypothetical protein 4444075..4444851 Escherichia coli O104:H4 str. 2011C-3493 13703548 YP_006780967.1 CDS O3K_21515 NC_018658.1 4445005 4445301 R hypothetical protein complement(4445005..4445301) Escherichia coli O104:H4 str. 2011C-3493 13703549 YP_006780968.1 CDS O3K_21520 NC_018658.1 4445515 4446801 R COG0498 Threonine synthase; threonine synthase complement(4445515..4446801) Escherichia coli O104:H4 str. 2011C-3493 13703550 YP_006780969.1 CDS O3K_21525 NC_018658.1 4446802 4447734 R COG0083 Homoserine kinase; homoserine kinase complement(4446802..4447734) Escherichia coli O104:H4 str. 2011C-3493 13703551 YP_006780970.1 CDS thrA NC_018658.1 4447736 4450198 R COG0527 Aspartokinases; bifunctional aspartokinase I/homoserine dehydrogenase I complement(4447736..4450198) Escherichia coli O104:H4 str. 2011C-3493 13703552 YP_006780971.1 CDS O3K_21535 NC_018658.1 4450558 4451244 R COG0565 rRNA methylase; putative RNA methyltransferase complement(4450558..4451244) Escherichia coli O104:H4 str. 2011C-3493 13703553 YP_006780972.1 CDS O3K_21540 NC_018658.1 4451880 4452596 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component response regulator 4451880..4452596 Escherichia coli O104:H4 str. 2011C-3493 13703554 YP_006780973.1 CDS O3K_21545 NC_018658.1 4452656 4454008 R COG4452 Inner membrane protein involved in colicin E2 resistance; inner membrane protein complement(4452656..4454008) Escherichia coli O104:H4 str. 2011C-3493 13703555 YP_006780974.1 CDS O3K_21550 NC_018658.1 4454066 4455490 R COG0642 Signal transduction histidine kinase; sensory histidine kinase CreC complement(4454066..4455490) Escherichia coli O104:H4 str. 2011C-3493 13703556 YP_006780975.1 CDS O3K_21555 NC_018658.1 4455490 4456179 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding response regulator CreB complement(4455490..4456179) Escherichia coli O104:H4 str. 2011C-3493 13703557 YP_006780976.1 CDS O3K_21560 NC_018658.1 4456192 4456665 R COG3045 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4456192..4456665) Escherichia coli O104:H4 str. 2011C-3493 13703558 YP_006780977.1 CDS O3K_21565 NC_018658.1 4456876 4457745 D COG2207 AraC-type DNA-binding domain-containing proteins; right oriC-binding transcriptional activator 4456876..4457745 Escherichia coli O104:H4 str. 2011C-3493 13703559 YP_006780978.1 CDS O3K_21570 NC_018658.1 4457742 4458389 R COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase complement(4457742..4458389) Escherichia coli O104:H4 str. 2011C-3493 13703560 YP_006780979.1 CDS O3K_21575 NC_018658.1 4458441 4458953 D COG1986 Uncharacterized conserved protein; inosine/xanthosine triphosphatase 4458441..4458953 Escherichia coli O104:H4 str. 2011C-3493 13703561 YP_006780980.1 CDS O3K_21580 NC_018658.1 4458995 4459321 R COG2973 Trp operon repressor; Trp operon repressor complement(4458995..4459321) Escherichia coli O104:H4 str. 2011C-3493 13703562 YP_006780981.1 CDS O3K_21585 NC_018658.1 4459411 4461348 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic murein transglycosylase complement(4459411..4461348) Escherichia coli O104:H4 str. 2011C-3493 13703563 YP_006780982.1 CDS O3K_21590 NC_018658.1 4461559 4463226 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 4461559..4463226 Escherichia coli O104:H4 str. 2011C-3493 13703564 YP_006780983.1 CDS O3K_21595 NC_018658.1 4463533 4464765 R COG1396 Predicted transcriptional regulators; bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase complement(4463533..4464765) Escherichia coli O104:H4 str. 2011C-3493 13703565 YP_006780984.1 CDS O3K_21600 NC_018658.1 4464786 4466168 R COG1066 Predicted ATP-dependent serine protease; DNA repair protein RadA complement(4464786..4466168) Escherichia coli O104:H4 str. 2011C-3493 13703566 YP_006780985.1 CDS serB NC_018658.1 4466217 4467185 R COG0560 Phosphoserine phosphatase; phosphoserine phosphatase complement(4466217..4467185) Escherichia coli O104:H4 str. 2011C-3493 13703567 YP_006780986.1 CDS O3K_21610 NC_018658.1 4467291 4467935 D COG3726 Uncharacterized membrane protein affecting hemolysin expression; hypothetical protein 4467291..4467935 Escherichia coli O104:H4 str. 2011C-3493 13703568 YP_006780987.1 CDS lplA NC_018658.1 4467963 4468979 D COG0095 Lipoate-protein ligase A; lipoate-protein ligase A 4467963..4468979 Escherichia coli O104:H4 str. 2011C-3493 13703569 YP_006780988.1 CDS O3K_21620 NC_018658.1 4469011 4469160 D hypothetical protein 4469011..4469160 Escherichia coli O104:H4 str. 2011C-3493 13703570 YP_006780989.1 CDS deoD NC_018658.1 4469435 4470154 R COG0813 Purine-nucleoside phosphorylase; purine nucleoside phosphorylase complement(4469435..4470154) Escherichia coli O104:H4 str. 2011C-3493 13703571 YP_006780990.1 CDS O3K_21630 NC_018658.1 4470234 4471457 R COG1015 Phosphopentomutase; phosphopentomutase complement(4470234..4471457) Escherichia coli O104:H4 str. 2011C-3493 13703572 YP_006780991.1 CDS deoA NC_018658.1 4471509 4472831 R COG0213 Thymidine phosphorylase; thymidine phosphorylase complement(4471509..4472831) Escherichia coli O104:H4 str. 2011C-3493 13703573 YP_006780992.1 CDS O3K_21640 NC_018658.1 4472909 4473688 R COG0274 Deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase complement(4472909..4473688) Escherichia coli O104:H4 str. 2011C-3493 13703574 YP_006780993.1 CDS O3K_21645 NC_018658.1 4473946 4475496 D hypothetical protein 4473946..4475496 Escherichia coli O104:H4 str. 2011C-3493 13703575 YP_006780994.1 CDS O3K_21650 NC_018658.1 4475468 4476331 D COG1180 Pyruvate-formate lyase-activating enzyme; putative pyruvate formate lyase activating enzyme 4475468..4476331 Escherichia coli O104:H4 str. 2011C-3493 13703576 YP_006780995.1 CDS O3K_21655 NC_018658.1 4476561 4477343 R COG0084 Mg-dependent DNase; putative deoxyribonuclease YjjV complement(4476561..4477343) Escherichia coli O104:H4 str. 2011C-3493 13703577 YP_006780996.1 CDS O3K_21660 NC_018658.1 4477340 4478413 R COG4667 Predicted esterase of the alpha-beta hydrolase superfamily; esterase complement(4477340..4478413) Escherichia coli O104:H4 str. 2011C-3493 13703578 YP_006780997.1 CDS O3K_21665 NC_018658.1 4478535 4478696 R hypothetical protein complement(4478535..4478696) Escherichia coli O104:H4 str. 2011C-3493 13703579 YP_006780998.1 CDS O3K_21670 NC_018658.1 4478823 4479428 R COG2823 Predicted periplasmic or secreted lipoprotein; hypothetical protein complement(4478823..4479428) Escherichia coli O104:H4 str. 2011C-3493 13703580 YP_006780999.1 CDS prfC NC_018658.1 4479821 4481410 R COG4108 Peptide chain release factor RF-3; peptide chain release factor 3 complement(4479821..4481410) Escherichia coli O104:H4 str. 2011C-3493 13703581 YP_006781000.1 CDS O3K_21680 NC_018658.1 4481501 4482178 R COG1011 Predicted hydrolase (HAD superfamily); dUMP phosphatase complement(4481501..4482178) Escherichia coli O104:H4 str. 2011C-3493 13703582 YP_006781001.1 CDS rimI NC_018658.1 4482193 4482639 R COG0456 Acetyltransferases; ribosomal-protein-alanine N-acetyltransferase complement(4482193..4482639) Escherichia coli O104:H4 str. 2011C-3493 13703583 YP_006781002.1 CDS O3K_21690 NC_018658.1 4482608 4483021 R COG3050 DNA polymerase III, psi subunit; DNA polymerase III subunit psi complement(4482608..4483021) Escherichia coli O104:H4 str. 2011C-3493 13703584 YP_006781003.1 CDS rsmC NC_018658.1 4483124 4484155 D COG2813 16S RNA G1207 methylase RsmC; 16S ribosomal RNA m2G1207 methyltransferase 4483124..4484155 Escherichia coli O104:H4 str. 2011C-3493 13703585 YP_006781004.1 CDS O3K_21700 NC_018658.1 4484825 4485061 R hypothetical protein complement(4484825..4485061) Escherichia coli O104:H4 str. 2011C-3493 13703589 YP_006781005.1 CDS O3K_21705 NC_018658.1 4485202 4485990 D COG4114 Uncharacterized Fe-S protein; ferric hydroximate transport ferric iron reductase 4485202..4485990 Escherichia coli O104:H4 str. 2011C-3493 13703590 YP_006781006.1 CDS O3K_21710 NC_018658.1 4486028 4486651 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator BglJ complement(4486028..4486651) Escherichia coli O104:H4 str. 2011C-3493 13703591 YP_006781007.1 CDS O3K_21715 NC_018658.1 4486663 4487388 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional regulator complement(4486663..4487388) Escherichia coli O104:H4 str. 2011C-3493 13703592 YP_006781008.1 CDS O3K_21720 NC_018658.1 4488009 4488779 D COG2966 Uncharacterized conserved protein; hypothetical protein 4488009..4488779 Escherichia coli O104:H4 str. 2011C-3493 13703593 YP_006781009.1 CDS O3K_21725 NC_018658.1 4488770 4489243 D COG3610 Uncharacterized conserved protein; hypothetical protein 4488770..4489243 Escherichia coli O104:H4 str. 2011C-3493 13703594 YP_006781010.1 CDS O3K_21730 NC_018658.1 4489350 4489889 D primosomal protein DnaI 4489350..4489889 Escherichia coli O104:H4 str. 2011C-3493 13703595 YP_006781011.1 CDS O3K_21735 NC_018658.1 4489892 4490629 D COG1484 DNA replication protein; DNA replication protein DnaC 4489892..4490629 Escherichia coli O104:H4 str. 2011C-3493 13703596 YP_006781012.1 CDS O3K_21740 NC_018658.1 4490675 4491172 D hypothetical protein 4490675..4491172 Escherichia coli O104:H4 str. 2011C-3493 13703597 YP_006781013.1 CDS O3K_21745 NC_018658.1 4491426 4493717 D COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; phosphoglycerol transferase I 4491426..4493717 Escherichia coli O104:H4 str. 2011C-3493 13703598 YP_006781014.1 CDS O3K_21750 NC_018658.1 4493858 4494880 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein complement(4493858..4494880) Escherichia coli O104:H4 str. 2011C-3493 13703599 YP_006781015.1 CDS O3K_21755 NC_018658.1 4495019 4495933 D COG1802 Transcriptional regulators; GntR family transcriptional regulator 4495019..4495933 Escherichia coli O104:H4 str. 2011C-3493 13703600 YP_006781016.1 CDS O3K_21760 NC_018658.1 4496148 4497509 D COG0477 Permeases of the major facilitator superfamily; transporter 4496148..4497509 Escherichia coli O104:H4 str. 2011C-3493 13703601 YP_006781017.1 CDS O3K_21765 NC_018658.1 4497558 4499222 R COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein I complement(4497558..4499222) Escherichia coli O104:H4 str. 2011C-3493 13703602 YP_006781018.1 CDS O3K_21770 NC_018658.1 4499599 4501749 D COG1966 Carbon starvation protein, predicted membrane protein; inner membrane protein 4499599..4501749 Escherichia coli O104:H4 str. 2011C-3493 13703603 YP_006781019.1 CDS O3K_21775 NC_018658.1 4501880 4502083 D COG2879 Uncharacterized small protein; hypothetical protein 4501880..4502083 Escherichia coli O104:H4 str. 2011C-3493 13703604 YP_006781020.1 CDS O3K_21780 NC_018658.1 4502094 4503050 D COG0523 Putative GTPases (G3E family); putative GTP-binding protein YjiA 4502094..4503050 Escherichia coli O104:H4 str. 2011C-3493 13703605 YP_006781021.1 CDS O3K_21785 NC_018658.1 4503119 4504771 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(4503119..4504771) Escherichia coli O104:H4 str. 2011C-3493 13703606 YP_006781022.1 CDS O3K_21790 NC_018658.1 4505049 4507481 D COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Type I restriction enzyme EcoAI R protein (R.EcoAI) 4505049..4507481 Escherichia coli O104:H4 str. 2011C-3493 13703607 YP_006781023.1 CDS O3K_21795 NC_018658.1 4507548 4509017 D COG0286 Type I restriction-modification system methyltransferase subunit; Type I restriction enzyme EcoEI M protein (M.EcoEI) 4507548..4509017 Escherichia coli O104:H4 str. 2011C-3493 13703608 YP_006781024.1 CDS O3K_21800 NC_018658.1 4509017 4510753 D COG0732 Restriction endonuclease S subunits; Type I restriction enzyme EcoAI specificity protein (S protein, S.EcoAI) 4509017..4510753 Escherichia coli O104:H4 str. 2011C-3493 13703609 YP_006781025.1 CDS O3K_21805 NC_018658.1 4510974 4511315 D endoribonuclease SymE 4510974..4511315 Escherichia coli O104:H4 str. 2011C-3493 13703610 YP_006781026.1 CDS O3K_21820 NC_018658.1 4513552 4513716 R hypothetical protein complement(4513552..4513716) Escherichia coli O104:H4 str. 2011C-3493 13703611 YP_006781027.1 CDS O3K_21825 NC_018658.1 4513893 4515305 D COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; DNA-binding transcriptional regulator/aminotransferase 4513893..4515305 Escherichia coli O104:H4 str. 2011C-3493 13703612 YP_006781028.1 CDS O3K_21830 NC_018658.1 4515548 4516504 R transposase complement(4515548..4516504) Escherichia coli O104:H4 str. 2011C-3493 13703613 YP_006781029.1 CDS O3K_21835 NC_018658.1 4516971 4518203 D COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein MdtM 4516971..4518203 Escherichia coli O104:H4 str. 2011C-3493 13703614 YP_006781030.1 CDS O3K_21840 NC_018658.1 4518277 4519524 D COG2733 Predicted membrane protein; inner membrane protein 4518277..4519524 Escherichia coli O104:H4 str. 2011C-3493 13703615 YP_006781031.1 CDS O3K_21845 NC_018658.1 4519640 4520791 D COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; putative 2-hydroxyglutaryl-CoA dehydratase 4519640..4520791 Escherichia coli O104:H4 str. 2011C-3493 13703616 YP_006781032.1 CDS O3K_21850 NC_018658.1 4520801 4521568 D COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); hypothetical protein 4520801..4521568 Escherichia coli O104:H4 str. 2011C-3493 13703617 YP_006781033.1 CDS O3K_21855 NC_018658.1 4521565 4521822 D hypothetical protein 4521565..4521822 Escherichia coli O104:H4 str. 2011C-3493 13703618 YP_006781034.1 CDS O3K_21860 NC_018658.1 4521776 4522747 D COG3204 Uncharacterized protein conserved in bacteria; hypothetical protein 4521776..4522747 Escherichia coli O104:H4 str. 2011C-3493 13703619 YP_006781035.1 CDS O3K_21865 NC_018658.1 4522815 4523993 D COG0477 Permeases of the major facilitator superfamily; inner membrane protein 4522815..4523993 Escherichia coli O104:H4 str. 2011C-3493 13703620 YP_006781036.1 CDS O3K_21870 NC_018658.1 4524006 4524560 R COG1859 RNA:NAD 2'-phosphotransferase; RNA 2'-phosphotransferase complement(4524006..4524560) Escherichia coli O104:H4 str. 2011C-3493 13703621 YP_006781037.1 CDS O3K_21875 NC_018658.1 4524810 4525493 D COG3314 Uncharacterized protein conserved in bacteria; hypothetical protein 4524810..4525493 Escherichia coli O104:H4 str. 2011C-3493 13703622 YP_006781038.1 CDS O3K_21880 NC_018658.1 4525490 4525951 D COG0700 Uncharacterized membrane protein; hypothetical protein 4525490..4525951 Escherichia coli O104:H4 str. 2011C-3493 13703623 YP_006781039.1 CDS O3K_21885 NC_018658.1 4525964 4527136 D COG0044 Dihydroorotase and related cyclic amidohydrolases; isoaspartyl dipeptidase 4525964..4527136 Escherichia coli O104:H4 str. 2011C-3493 13703624 YP_006781040.1 CDS O3K_21890 NC_018658.1 4527201 4528112 D COG0583 Transcriptional regulator; cell density-dependent motility repressor 4527201..4528112 Escherichia coli O104:H4 str. 2011C-3493 13703625 YP_006781041.1 CDS iraD NC_018658.1 4528105 4528497 R DNA replication/recombination/repair protein complement(4528105..4528497) Escherichia coli O104:H4 str. 2011C-3493 13703626 YP_006781042.1 CDS O3K_21900 NC_018658.1 4529169 4529999 D hypothetical protein 4529169..4529999 Escherichia coli O104:H4 str. 2011C-3493 13703627 YP_006781043.1 CDS O3K_21905 NC_018658.1 4530140 4530913 R COG2186 Transcriptional regulators; DNA-binding transcriptional repressor UxuR complement(4530140..4530913) Escherichia coli O104:H4 str. 2011C-3493 13703628 YP_006781044.1 CDS O3K_21910 NC_018658.1 4530912 4531106 D hypothetical protein 4530912..4531106 Escherichia coli O104:H4 str. 2011C-3493 13703629 YP_006781045.1 CDS O3K_21915 NC_018658.1 4531128 4532588 R COG0246 Mannitol-1-phosphate/altronate dehydrogenases; D-mannonate oxidoreductase complement(4531128..4532588) Escherichia coli O104:H4 str. 2011C-3493 13703630 YP_006781046.1 CDS O3K_21920 NC_018658.1 4532669 4533853 R COG1312 D-mannonate dehydratase; mannonate dehydratase complement(4532669..4533853) Escherichia coli O104:H4 str. 2011C-3493 13703631 YP_006781047.1 CDS O3K_21925 NC_018658.1 4534193 4535536 D COG2610 H+/gluconate symporter and related permeases; fructuronate transporter 4534193..4535536 Escherichia coli O104:H4 str. 2011C-3493 13703632 YP_006781048.1 CDS O3K_21930 NC_018658.1 4535935 4536210 D COG3677 Transposase and inactivated derivatives; IS1 repressor protein insA 4535935..4536210 Escherichia coli O104:H4 str. 2011C-3493 13703633 YP_006781049.1 CDS O3K_21935 NC_018658.1 4536129 4536632 D COG1662 Transposase and inactivated derivatives, IS1 family; putative IS1 transposase InsAB' 4536129..4536632 Escherichia coli O104:H4 str. 2011C-3493 13703634 YP_006781050.1 CDS O3K_21940 NC_018658.1 4536643 4537320 R hypothetical protein complement(4536643..4537320) Escherichia coli O104:H4 str. 2011C-3493 13703635 YP_006781051.1 CDS O3K_21945 NC_018658.1 4538521 4539129 R COG1960 Acyl-CoA dehydrogenases; hypothetical protein complement(4538521..4539129) Escherichia coli O104:H4 str. 2011C-3493 13703636 YP_006781052.1 CDS O3K_21950 NC_018658.1 4539218 4539424 R COG3311 Predicted transcriptional regulator; hypothetical protein complement(4539218..4539424) Escherichia coli O104:H4 str. 2011C-3493 13703637 YP_006781053.1 CDS O3K_21955 NC_018658.1 4539565 4539831 D hypothetical protein 4539565..4539831 Escherichia coli O104:H4 str. 2011C-3493 13703638 YP_006781054.1 CDS O3K_21960 NC_018658.1 4540132 4540308 D hemolysin expression modulating protein Hha 4540132..4540308 Escherichia coli O104:H4 str. 2011C-3493 13703639 YP_006781055.1 CDS O3K_21965 NC_018658.1 4541049 4541618 D hypothetical protein 4541049..4541618 Escherichia coli O104:H4 str. 2011C-3493 13703640 YP_006781056.1 CDS O3K_21970 NC_018658.1 4541872 4542279 D COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 4541872..4542279 Escherichia coli O104:H4 str. 2011C-3493 13703641 YP_006781057.1 CDS O3K_21975 NC_018658.1 4542267 4542701 D hypothetical protein 4542267..4542701 Escherichia coli O104:H4 str. 2011C-3493 13703642 YP_006781058.1 CDS O3K_21980 NC_018658.1 4543035 4543436 D COG2963 Transposase and inactivated derivatives; transposase, IS3 family protein 4543035..4543436 Escherichia coli O104:H4 str. 2011C-3493 13703643 YP_006781059.1 CDS O3K_21985 NC_018658.1 4543433 4543780 D COG3436 Transposase and inactivated derivatives; transposase 4543433..4543780 Escherichia coli O104:H4 str. 2011C-3493 13703644 YP_006781060.1 CDS O3K_21990 NC_018658.1 4543830 4545215 D COG3436 Transposase and inactivated derivatives; transposase 4543830..4545215 Escherichia coli O104:H4 str. 2011C-3493 13703645 YP_006781061.1 CDS O3K_21995 NC_018658.1 4545454 4546812 R COG4222 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4545454..4546812) Escherichia coli O104:H4 str. 2011C-3493 13703646 YP_006781062.1 CDS O3K_22000 NC_018658.1 4547191 4547400 D hypothetical protein 4547191..4547400 Escherichia coli O104:H4 str. 2011C-3493 13703647 YP_006781063.1 CDS O3K_22005 NC_018658.1 4547563 4547820 R hypothetical protein complement(4547563..4547820) Escherichia coli O104:H4 str. 2011C-3493 13703648 YP_006781064.1 CDS O3K_22010 NC_018658.1 4548738 4549259 D COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor FecI 4548738..4549259 Escherichia coli O104:H4 str. 2011C-3493 13703649 YP_006781065.1 CDS O3K_22015 NC_018658.1 4549256 4550209 D COG3712 Fe2+-dicitrate sensor, membrane component; fec operon regulator FecR 4549256..4550209 Escherichia coli O104:H4 str. 2011C-3493 13703650 YP_006781066.1 CDS O3K_22020 NC_018658.1 4550296 4552620 D COG4772 Outer membrane receptor for Fe3+-dicitrate; ferric citrate outer membrane transporter, KpLE2 phage-like element 4550296..4552620 Escherichia coli O104:H4 str. 2011C-3493 13703651 YP_006781067.1 CDS fecB NC_018658.1 4552665 4553567 D COG4594 ABC-type Fe3+-citrate transport system, periplasmic component; iron-dicitrate transporter substrate-binding subunit 4552665..4553567 Escherichia coli O104:H4 str. 2011C-3493 13703652 YP_006781068.1 CDS fecC NC_018658.1 4553564 4554562 D COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-dicitrate transporter permease subunit 4553564..4554562 Escherichia coli O104:H4 str. 2011C-3493 13703653 YP_006781069.1 CDS fecD NC_018658.1 4554559 4555515 D COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-dicitrate transporter subunit FecD 4554559..4555515 Escherichia coli O104:H4 str. 2011C-3493 13703654 YP_006781070.1 CDS fecE NC_018658.1 4555516 4556283 D COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-dicitrate transporter ATP-binding subunit 4555516..4556283 Escherichia coli O104:H4 str. 2011C-3493 13703655 YP_006781071.1 CDS O3K_22045 NC_018658.1 4556841 4557254 R COG2085 Predicted dinucleotide-binding enzymes; KpLE2 phage-like element complement(4556841..4557254) Escherichia coli O104:H4 str. 2011C-3493 13703656 YP_006781072.1 CDS O3K_22055 NC_018658.1 4557749 4559272 R COG3344 Retron-type reverse transcriptase; putative group II intron encoded reverse transcriptase/maturase complement(4557749..4559272) Escherichia coli O104:H4 str. 2011C-3493 13703657 YP_006781073.1 CDS O3K_22065 NC_018658.1 4560345 4560647 R COG2963 Transposase and inactivated derivatives; IS911; transposase ORF A, IS911 complement(4560345..4560647) Escherichia coli O104:H4 str. 2011C-3493 13703658 YP_006781074.1 CDS O3K_22070 NC_018658.1 4560854 4561675 D COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase family protein 4560854..4561675 Escherichia coli O104:H4 str. 2011C-3493 13703659 YP_006781075.1 CDS O3K_22075 NC_018658.1 4561678 4562766 D COG0438 Glycosyltransferase; Glycosyl transferase 4561678..4562766 Escherichia coli O104:H4 str. 2011C-3493 13703660 YP_006781076.1 CDS O3K_22080 NC_018658.1 4562771 4563721 D COG2990 Uncharacterized protein conserved in bacteria; regulator of virG protein 4562771..4563721 Escherichia coli O104:H4 str. 2011C-3493 13703661 YP_006781077.1 CDS O3K_22085 NC_018658.1 4563786 4564730 D COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 4563786..4564730 Escherichia coli O104:H4 str. 2011C-3493 13703662 YP_006781078.1 CDS O3K_22090 NC_018658.1 4565337 4566050 D COG2801 Transposase and inactivated derivatives; hypothetical protein 4565337..4566050 Escherichia coli O104:H4 str. 2011C-3493 13703663 YP_006781079.1 CDS O3K_22095 NC_018658.1 4566198 4568201 D COG1292 Choline-glycine betaine transporter; betaine-carnitine-choline transporter family member BetU 4566198..4568201 Escherichia coli O104:H4 str. 2011C-3493 13703664 YP_006781080.1 CDS O3K_22100 NC_018658.1 4568264 4569541 D COG4325 Predicted membrane protein; hypothetical protein 4568264..4569541 Escherichia coli O104:H4 str. 2011C-3493 13703665 YP_006781081.1 CDS O3K_22105 NC_018658.1 4569787 4570443 D COG1309 Transcriptional regulator; HTH regulator, TetR family protein 4569787..4570443 Escherichia coli O104:H4 str. 2011C-3493 13703666 YP_006781082.1 CDS O3K_22115 NC_018658.1 4570891 4571316 D COG2963 Transposase and inactivated derivatives; IS66 transposase 4570891..4571316 Escherichia coli O104:H4 str. 2011C-3493 13703667 YP_006781083.1 CDS O3K_22120 NC_018658.1 4571313 4571663 D COG3436 Transposase and inactivated derivatives; IS66 transposase 4571313..4571663 Escherichia coli O104:H4 str. 2011C-3493 13703668 YP_006781084.1 CDS O3K_22125 NC_018658.1 4571694 4573307 D COG3436 Transposase and inactivated derivatives; putative IS element transposase 4571694..4573307 Escherichia coli O104:H4 str. 2011C-3493 13703669 YP_006781085.1 CDS O3K_22130 NC_018658.1 4573383 4573646 R hypothetical protein complement(4573383..4573646) Escherichia coli O104:H4 str. 2011C-3493 13703670 YP_006781086.1 CDS O3K_22135 NC_018658.1 4574274 4574390 D hypothetical protein 4574274..4574390 Escherichia coli O104:H4 str. 2011C-3493 13703671 YP_006781087.1 CDS O3K_22140 NC_018658.1 4574391 4574489 D acetolactate synthase 1 regulatory subunit 4574391..4574489 Escherichia coli O104:H4 str. 2011C-3493 13703672 YP_006781088.1 CDS O3K_22145 NC_018658.1 4574491 4575273 R COG1349 Transcriptional regulators of sugar metabolism; transcriptional regulator complement(4574491..4575273) Escherichia coli O104:H4 str. 2011C-3493 13703673 YP_006781089.1 CDS O3K_22150 NC_018658.1 4575579 4576499 D COG0524 Sugar kinases, ribokinase family; ribokinase sugar kinase 4575579..4576499 Escherichia coli O104:H4 str. 2011C-3493 13703674 YP_006781090.1 CDS O3K_22155 NC_018658.1 4576527 4577843 D COG0738 Fucose permease; L-fucose permease 4576527..4577843 Escherichia coli O104:H4 str. 2011C-3493 13703675 YP_006781091.1 CDS O3K_22160 NC_018658.1 4577855 4578868 D Deoxyribose specific mutarotase 4577855..4578868 Escherichia coli O104:H4 str. 2011C-3493 13703676 YP_006781092.1 CDS O3K_22170 NC_018658.1 4579791 4581047 R COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC complement(4579791..4581047) Escherichia coli O104:H4 str. 2011C-3493 13703677 YP_006781093.1 CDS O3K_22175 NC_018658.1 4581060 4581347 R COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system transporter subunit IIB complement(4581060..4581347) Escherichia coli O104:H4 str. 2011C-3493 13703678 YP_006781094.1 CDS O3K_22180 NC_018658.1 4581363 4581806 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system transporter subunit IIA complement(4581363..4581806) Escherichia coli O104:H4 str. 2011C-3493 13703679 YP_006781095.1 CDS O3K_22185 NC_018658.1 4582077 4583108 D COG1609 Transcriptional regulators; transcriptional regulator 4582077..4583108 Escherichia coli O104:H4 str. 2011C-3493 13703680 YP_006781096.1 CDS O3K_22195 NC_018658.1 4584288 4584446 R COG0207 Thymidylate synthase; hypothetical protein complement(4584288..4584446) Escherichia coli O104:H4 str. 2011C-3493 13703681 YP_006781097.1 CDS O3K_22200 NC_018658.1 4584598 4584870 D hypothetical protein 4584598..4584870 Escherichia coli O104:H4 str. 2011C-3493 13703682 YP_006781098.1 CDS O3K_22205 NC_018658.1 4584878 4585099 R hypothetical protein complement(4584878..4585099) Escherichia coli O104:H4 str. 2011C-3493 13703683 YP_006781099.1 CDS O3K_22210 NC_018658.1 4585078 4585242 R hypothetical protein complement(4585078..4585242) Escherichia coli O104:H4 str. 2011C-3493 13703684 YP_006781100.1 CDS O3K_22215 NC_018658.1 4585354 4586043 R COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; N-acetylmannosamine-6-phosphate 2-epimerase complement(4585354..4586043) Escherichia coli O104:H4 str. 2011C-3493 13703685 YP_006781101.1 CDS O3K_22220 NC_018658.1 4586043 4587599 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose-specific transporter subunit IIABC complement(4586043..4587599) Escherichia coli O104:H4 str. 2011C-3493 13703686 YP_006781102.1 CDS O3K_22225 NC_018658.1 4587765 4588589 D COG1737 Transcriptional regulators; transcriptional regulator 4587765..4588589 Escherichia coli O104:H4 str. 2011C-3493 13703687 YP_006781103.1 CDS O3K_22230 NC_018658.1 4588761 4589264 R COG1662 Transposase and inactivated derivatives, IS1 family; IS1; transposase ORF B, IS1 complement(4588761..4589264) Escherichia coli O104:H4 str. 2011C-3493 13703688 YP_006781104.1 CDS O3K_22235 NC_018658.1 4589183 4589458 R COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA, KpLE2 phage-like element complement(4589183..4589458) Escherichia coli O104:H4 str. 2011C-3493 13703689 YP_006781105.1 CDS O3K_22240 NC_018658.1 4589500 4590129 D hypothetical protein 4589500..4590129 Escherichia coli O104:H4 str. 2011C-3493 13703690 YP_006781106.1 CDS O3K_22245 NC_018658.1 4590180 4591256 R COG3177 Uncharacterized conserved protein; Filamentation induced by cAMP protein Fic complement(4590180..4591256) Escherichia coli O104:H4 str. 2011C-3493 13703691 YP_006781107.1 CDS O3K_22250 NC_018658.1 4591746 4592042 R COG1396 Predicted transcriptional regulators; transcriptional regulator complement(4591746..4592042) Escherichia coli O104:H4 str. 2011C-3493 13703692 YP_006781108.1 CDS O3K_22255 NC_018658.1 4592962 4593237 D COG3677 Transposase and inactivated derivatives; InsA 4592962..4593237 Escherichia coli O104:H4 str. 2011C-3493 13703693 YP_006781109.1 CDS O3K_22260 NC_018658.1 4593156 4593659 D COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 4593156..4593659 Escherichia coli O104:H4 str. 2011C-3493 13703694 YP_006781110.1 CDS O3K_22265 NC_018658.1 4593713 4594093 D COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); hypothetical protein 4593713..4594093 Escherichia coli O104:H4 str. 2011C-3493 13703695 YP_006781111.1 CDS O3K_22270 NC_018658.1 4594338 4595210 D COG3440 Predicted restriction endonuclease; hypothetical protein 4594338..4595210 Escherichia coli O104:H4 str. 2011C-3493 13703696 YP_006781112.1 CDS O3K_22275 NC_018658.1 4595578 4595871 D hypothetical protein 4595578..4595871 Escherichia coli O104:H4 str. 2011C-3493 13703697 YP_006781113.1 CDS O3K_22280 NC_018658.1 4595957 4597162 D COG4227 Antirestriction protein; hypothetical protein 4595957..4597162 Escherichia coli O104:H4 str. 2011C-3493 13703698 YP_006781114.1 CDS O3K_22285 NC_018658.1 4597172 4598791 D COG3481 Predicted HD-superfamily hydrolase; hypothetical protein 4597172..4598791 Escherichia coli O104:H4 str. 2011C-3493 13703699 YP_006781115.1 CDS O3K_22290 NC_018658.1 4598781 4599707 D COG0582 Integrase; hypothetical protein 4598781..4599707 Escherichia coli O104:H4 str. 2011C-3493 13703700 YP_006781116.1 CDS O3K_22295 NC_018658.1 4600137 4601156 D COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase, Zn-dependent and NAD(P)-binding protein 4600137..4601156 Escherichia coli O104:H4 str. 2011C-3493 13703702 YP_006781117.1 CDS idnK NC_018658.1 4601160 4601723 R COG3265 Gluconate kinase; D-gluconate kinase complement(4601160..4601723) Escherichia coli O104:H4 str. 2011C-3493 13703703 YP_006781118.1 CDS O3K_22305 NC_018658.1 4601940 4602971 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; L-idonate 5-dehydrogenase 4601940..4602971 Escherichia coli O104:H4 str. 2011C-3493 13703704 YP_006781119.1 CDS O3K_22310 NC_018658.1 4602995 4603759 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); gluconate 5-dehydrogenase 4602995..4603759 Escherichia coli O104:H4 str. 2011C-3493 13703705 YP_006781120.1 CDS O3K_22315 NC_018658.1 4603824 4605143 D COG2610 H+/gluconate symporter and related permeases; Gnt-II system L-idonate transporter 4603824..4605143 Escherichia coli O104:H4 str. 2011C-3493 13703706 YP_006781121.1 CDS O3K_22320 NC_018658.1 4605210 4606208 D COG1609 Transcriptional regulators; DNA-binding transcriptional repressor, 5-gluconate-binding protein 4605210..4606208 Escherichia coli O104:H4 str. 2011C-3493 13703707 YP_006781122.1 CDS O3K_22325 NC_018658.1 4606286 4607788 D COG0433 Predicted ATPase; ATPase 4606286..4607788 Escherichia coli O104:H4 str. 2011C-3493 13703708 YP_006781123.1 CDS O3K_22330 NC_018658.1 4607907 4608989 R COG0795 Predicted permeases; lipopolysaccharide ABC transporter permease complement(4607907..4608989) Escherichia coli O104:H4 str. 2011C-3493 13703709 YP_006781124.1 CDS O3K_22335 NC_018658.1 4608989 4610089 R COG0795 Predicted permeases; lipopolysaccharide ABC transporter permease LptF complement(4608989..4610089) Escherichia coli O104:H4 str. 2011C-3493 13703710 YP_006781125.1 CDS O3K_22340 NC_018658.1 4610356 4611867 D COG0260 Leucyl aminopeptidase; multifunctional aminopeptidase A 4610356..4611867 Escherichia coli O104:H4 str. 2011C-3493 13703711 YP_006781126.1 CDS O3K_22345 NC_018658.1 4612001 4612444 D COG2927 DNA polymerase III, chi subunit; DNA polymerase III subunit chi 4612001..4612444 Escherichia coli O104:H4 str. 2011C-3493 13703712 YP_006781127.1 CDS valS NC_018658.1 4612444 4615299 D COG0525 Valyl-tRNA synthetase; valyl-tRNA synthetase 4612444..4615299 Escherichia coli O104:H4 str. 2011C-3493 13703713 YP_006781128.1 CDS O3K_22355 NC_018658.1 4615355 4616551 R COG4269 Predicted membrane protein; hypothetical protein complement(4615355..4616551) Escherichia coli O104:H4 str. 2011C-3493 13703714 YP_006781129.1 CDS O3K_22360 NC_018658.1 4616744 4617247 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 4616744..4617247 Escherichia coli O104:H4 str. 2011C-3493 13703715 YP_006781130.1 CDS O3K_22365 NC_018658.1 4617293 4617709 R COG3076 Uncharacterized protein conserved in bacteria; RNase E inhibitor protein complement(4617293..4617709) Escherichia coli O104:H4 str. 2011C-3493 13703716 YP_006781131.1 CDS O3K_22370 NC_018658.1 4617871 4618875 D COG0078 Ornithine carbamoyltransferase; ornithine carbamoyltransferase subunit I 4617871..4618875 Escherichia coli O104:H4 str. 2011C-3493 13703717 YP_006781132.1 CDS O3K_26527 NC_018658.1 4619218 4620537 R Protein YjgL, putative CCAAT-box DNA binding protein complement(4619218..4620537) Escherichia coli O104:H4 str. 2011C-3493 13703718 YP_006781133.1 CDS O3K_22385 NC_018658.1 4620660 4621112 R COG2731 Beta-galactosidase, beta subunit; hypothetical protein complement(4620660..4621112) Escherichia coli O104:H4 str. 2011C-3493 13700922 YP_006781134.1 CDS O3K_22390 NC_018658.1 4621257 4621850 R COG1309 Transcriptional regulator; transcriptional regulator complement(4621257..4621850) Escherichia coli O104:H4 str. 2011C-3493 13703719 YP_006781135.1 CDS O3K_22395 NC_018658.1 4621921 4622634 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 4621921..4622634 Escherichia coli O104:H4 str. 2011C-3493 13703720 YP_006781136.1 CDS O3K_22400 NC_018658.1 4622765 4623160 D COG0251 Putative translation initiation inhibitor, yjgF family; putative mRNA endoribonuclease 4622765..4623160 Escherichia coli O104:H4 str. 2011C-3493 13703721 YP_006781137.1 CDS O3K_22405 NC_018658.1 4623384 4623575 D pyrBI operon leader peptide 4623384..4623575 Escherichia coli O104:H4 str. 2011C-3493 13703722 YP_006781138.1 CDS pyrB NC_018658.1 4623579 4624514 D COG0540 Aspartate carbamoyltransferase, catalytic chain; aspartate carbamoyltransferase catalytic subunit 4623579..4624514 Escherichia coli O104:H4 str. 2011C-3493 13703723 YP_006781139.1 CDS O3K_22415 NC_018658.1 4624527 4624988 D COG1781 Aspartate carbamoyltransferase, regulatory subunit; aspartate carbamoyltransferase regulatory subunit 4624527..4624988 Escherichia coli O104:H4 str. 2011C-3493 13703724 YP_006781140.1 CDS O3K_22420 NC_018658.1 4625061 4625447 D COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 4625061..4625447 Escherichia coli O104:H4 str. 2011C-3493 13703725 YP_006781141.1 CDS O3K_22425 NC_018658.1 4625724 4626704 D COG3547 Transposase and inactivated derivatives; IS621 transposase 4625724..4626704 Escherichia coli O104:H4 str. 2011C-3493 13703726 YP_006781142.1 CDS O3K_22430 NC_018658.1 4626932 4629628 R COG0474 Cation transport ATPase; magnesium-transporting ATPase MgtA complement(4626932..4629628) Escherichia coli O104:H4 str. 2011C-3493 13703727 YP_006781143.1 CDS treR NC_018658.1 4630007 4630954 D COG1609 Transcriptional regulators; trehalose repressor 4630007..4630954 Escherichia coli O104:H4 str. 2011C-3493 13703728 YP_006781144.1 CDS O3K_22440 NC_018658.1 4631076 4632494 D COG1264 Phosphotransferase system IIB components; PTS system trehalose(maltose)-specific transporter subunit IIBC 4631076..4632494 Escherichia coli O104:H4 str. 2011C-3493 13703729 YP_006781145.1 CDS O3K_22445 NC_018658.1 4632544 4634199 D COG0366 Glycosidases; trehalose-6-phosphate hydrolase 4632544..4634199 Escherichia coli O104:H4 str. 2011C-3493 13703730 YP_006781146.1 CDS O3K_22450 NC_018658.1 4634602 4636740 D COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; anaerobic ribonucleoside triphosphate reductase 4634602..4636740 Escherichia coli O104:H4 str. 2011C-3493 13703731 YP_006781147.1 CDS nrdG NC_018658.1 4636898 4637362 D COG0602 Organic radical activating enzymes; anaerobic ribonucleotide reductase-activating protein 4636898..4637362 Escherichia coli O104:H4 str. 2011C-3493 13703732 YP_006781148.1 CDS O3K_22460 NC_018658.1 4637407 4637793 R COG3783 Soluble cytochrome b562; cytochrome b562 complement(4637407..4637793) Escherichia coli O104:H4 str. 2011C-3493 13703733 YP_006781149.1 CDS O3K_22465 NC_018658.1 4637976 4639316 R COG0312 Predicted Zn-dependent proteases and their inactivated homologs; peptidase PmbA complement(4637976..4639316) Escherichia coli O104:H4 str. 2011C-3493 13703734 YP_006781150.1 CDS O3K_22470 NC_018658.1 4639422 4639973 D COG3028 Uncharacterized protein conserved in bacteria; hypothetical protein 4639422..4639973 Escherichia coli O104:H4 str. 2011C-3493 13703735 YP_006781151.1 CDS O3K_22475 NC_018658.1 4640124 4641497 R COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase complement(4640124..4641497) Escherichia coli O104:H4 str. 2011C-3493 13703736 YP_006781152.1 CDS O3K_22480 NC_018658.1 4641673 4642671 D COG0158 Fructose-1,6-bisphosphatase; fructose-1,6-bisphosphatase 4641673..4642671 Escherichia coli O104:H4 str. 2011C-3493 13703737 YP_006781153.1 CDS O3K_22485 NC_018658.1 4642704 4643699 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; inner membrane ABC transporter permease YjfF complement(4642704..4643699) Escherichia coli O104:H4 str. 2011C-3493 13703738 YP_006781154.1 CDS O3K_22490 NC_018658.1 4643686 4644708 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease complement(4643686..4644708) Escherichia coli O104:H4 str. 2011C-3493 13703739 YP_006781155.1 CDS O3K_22495 NC_018658.1 4644722 4646224 R COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein complement(4644722..4646224) Escherichia coli O104:H4 str. 2011C-3493 13703740 YP_006781156.1 CDS O3K_22500 NC_018658.1 4646534 4647490 R COG1879 ABC-type sugar transport system, periplasmic component; putative sugar transporter subunit complement(4646534..4647490) Escherichia coli O104:H4 str. 2011C-3493 13703741 YP_006781157.1 CDS O3K_22505 NC_018658.1 4647800 4648330 D COG0221 Inorganic pyrophosphatase; inorganic pyrophosphatase 4647800..4648330 Escherichia coli O104:H4 str. 2011C-3493 13703742 YP_006781158.1 CDS O3K_22510 NC_018658.1 4648410 4648760 R COG2337 Growth inhibitor; toxin ChpB complement(4648410..4648760) Escherichia coli O104:H4 str. 2011C-3493 13703743 YP_006781159.1 CDS O3K_22515 NC_018658.1 4648754 4649005 R COG2336 Growth regulator; antitoxin ChpS complement(4648754..4649005) Escherichia coli O104:H4 str. 2011C-3493 13703744 YP_006781160.1 CDS O3K_22520 NC_018658.1 4649217 4649558 R COG2105 Uncharacterized conserved protein; hypothetical protein complement(4649217..4649558) Escherichia coli O104:H4 str. 2011C-3493 13703745 YP_006781161.1 CDS O3K_22525 NC_018658.1 4649561 4653340 R COG2911 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4649561..4653340) Escherichia coli O104:H4 str. 2011C-3493 13703746 YP_006781162.1 CDS O3K_22530 NC_018658.1 4653337 4655070 R COG0729 Outer membrane protein; surface antigen complement(4653337..4655070) Escherichia coli O104:H4 str. 2011C-3493 13703747 YP_006781163.1 CDS O3K_22535 NC_018658.1 4655040 4655168 R COG1131 ABC-type multidrug transport system, ATPase component; hypothetical protein complement(4655040..4655168) Escherichia coli O104:H4 str. 2011C-3493 13703748 YP_006781164.1 CDS O3K_22540 NC_018658.1 4655276 4655914 D COG0225 Peptide methionine sulfoxide reductase; methionine sulfoxide reductase A 4655276..4655914 Escherichia coli O104:H4 str. 2011C-3493 13703749 YP_006781165.1 CDS O3K_22545 NC_018658.1 4656237 4657580 D COG1253 Hemolysins and related proteins containing CBS domains; inner membrane protein 4656237..4657580 Escherichia coli O104:H4 str. 2011C-3493 13703750 YP_006781166.1 CDS O3K_22550 NC_018658.1 4657642 4657848 R COG1117 ABC-type phosphate transport system, ATPase component; hypothetical protein complement(4657642..4657848) Escherichia coli O104:H4 str. 2011C-3493 13703751 YP_006781167.1 CDS O3K_22555 NC_018658.1 4658173 4658730 D COG3054 Predicted transcriptional regulator; transcriptional regulator 4658173..4658730 Escherichia coli O104:H4 str. 2011C-3493 13703752 YP_006781168.1 CDS O3K_22560 NC_018658.1 4658720 4659460 R COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; adenosine-3'(2'),5'-bisphosphate nucleotidase complement(4658720..4659460) Escherichia coli O104:H4 str. 2011C-3493 13703753 YP_006781169.1 CDS cpdB NC_018658.1 4659650 4661593 D COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4659650..4661593 Escherichia coli O104:H4 str. 2011C-3493 13703754 YP_006781170.1 CDS O3K_22570 NC_018658.1 4661722 4662102 R COG1733 Predicted transcriptional regulators; hypothetical protein complement(4661722..4662102) Escherichia coli O104:H4 str. 2011C-3493 13703755 YP_006781171.1 CDS O3K_22575 NC_018658.1 4662191 4663051 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD(P)H:quinone oxidoreductase 4662191..4663051 Escherichia coli O104:H4 str. 2011C-3493 13703756 YP_006781172.1 CDS O3K_22580 NC_018658.1 4663159 4664124 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; inner membrane protein 4663159..4664124 Escherichia coli O104:H4 str. 2011C-3493 13703757 YP_006781173.1 CDS O3K_22585 NC_018658.1 4664232 4664894 D COG2846 Regulator of cell morphogenesis and NO signaling; iron-sulfur cluster repair di-iron protein 4664232..4664894 Escherichia coli O104:H4 str. 2011C-3493 13703758 YP_006781174.1 CDS O3K_22590 NC_018658.1 4664939 4666351 R COG1113 Gamma-aminobutyrate permease and related permeases; D-alanine/D-serine/glycine permease complement(4664939..4666351) Escherichia coli O104:H4 str. 2011C-3493 13703759 YP_006781175.1 CDS O3K_22595 NC_018658.1 4666660 4667280 R COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; peptidyl-prolyl cis-trans isomerase complement(4666660..4667280) Escherichia coli O104:H4 str. 2011C-3493 13703760 YP_006781176.1 CDS O3K_22600 NC_018658.1 4667499 4668137 D COG3061 Cell envelope opacity-associated protein A; putative cell envelope opacity-associated protein 4667499..4668137 Escherichia coli O104:H4 str. 2011C-3493 13703761 YP_006781177.1 CDS O3K_22605 NC_018658.1 4668272 4669480 R COG0675 Transposase and inactivated derivatives; transposase complement(4668272..4669480) Escherichia coli O104:H4 str. 2011C-3493 13703762 YP_006781178.1 CDS O3K_22610 NC_018658.1 4669488 4669919 D COG1943 Transposase and inactivated derivatives; transposase 4669488..4669919 Escherichia coli O104:H4 str. 2011C-3493 13699784 YP_006781179.1 CDS O3K_22615 NC_018658.1 4670542 4671336 D hypothetical protein 4670542..4671336 Escherichia coli O104:H4 str. 2011C-3493 13699785 YP_006781180.1 CDS rplI NC_018658.1 4671407 4671856 R COG0359 Ribosomal protein L9; 50S ribosomal protein L9 complement(4671407..4671856) Escherichia coli O104:H4 str. 2011C-3493 13699786 YP_006781181.1 CDS rpsR NC_018658.1 4671898 4672125 R COG0238 Ribosomal protein S18; 30S ribosomal protein S18 complement(4671898..4672125) Escherichia coli O104:H4 str. 2011C-3493 13699787 YP_006781182.1 CDS O3K_22630 NC_018658.1 4672130 4672444 R COG2965 Primosomal replication protein N; primosomal replication protein N complement(4672130..4672444) Escherichia coli O104:H4 str. 2011C-3493 13699788 YP_006781183.1 CDS rpsF NC_018658.1 4672451 4672846 R COG0360 Ribosomal protein S6; 30S ribosomal protein S6 complement(4672451..4672846) Escherichia coli O104:H4 str. 2011C-3493 13699789 YP_006781184.1 CDS O3K_22640 NC_018658.1 4673173 4673448 D hypothetical protein 4673173..4673448 Escherichia coli O104:H4 str. 2011C-3493 13699790 YP_006781185.1 CDS O3K_22645 NC_018658.1 4673523 4674074 R COG3477 Predicted periplasmic/secreted protein; Inner membrane protein yagU complement(4673523..4674074) Escherichia coli O104:H4 str. 2011C-3493 13699791 YP_006781186.1 CDS sgaE NC_018658.1 4674171 4674857 R COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase complement(4674171..4674857) Escherichia coli O104:H4 str. 2011C-3493 13699792 YP_006781187.1 CDS O3K_22655 NC_018658.1 4674857 4675711 R COG3623 Putative L-xylulose-5-phosphate 3-epimerase; L-xylulose 5-phosphate 3-epimerase complement(4674857..4675711) Escherichia coli O104:H4 str. 2011C-3493 13699793 YP_006781188.1 CDS ulaD NC_018658.1 4675721 4676371 R COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-keto-L-gulonate-6-phosphate decarboxylase complement(4675721..4676371) Escherichia coli O104:H4 str. 2011C-3493 13699794 YP_006781189.1 CDS O3K_22665 NC_018658.1 4676385 4676849 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system L-ascorbate-specific transporter subunit IIA complement(4676385..4676849) Escherichia coli O104:H4 str. 2011C-3493 13699795 YP_006781190.1 CDS O3K_22670 NC_018658.1 4676859 4677164 R COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system L-ascorbate-specific transporter subunit IIB complement(4676859..4677164) Escherichia coli O104:H4 str. 2011C-3493 13699796 YP_006781191.1 CDS ulaA NC_018658.1 4677180 4678577 R COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC complement(4677180..4678577) Escherichia coli O104:H4 str. 2011C-3493 13699797 YP_006781192.1 CDS O3K_22680 NC_018658.1 4678932 4679996 D COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; L-ascorbate 6-phosphate lactonase 4678932..4679996 Escherichia coli O104:H4 str. 2011C-3493 13699798 YP_006781193.1 CDS O3K_22685 NC_018658.1 4680104 4680859 D COG1349 Transcriptional regulators of sugar metabolism; transcriptional repressor UlaR 4680104..4680859 Escherichia coli O104:H4 str. 2011C-3493 13699799 YP_006781194.1 CDS O3K_22690 NC_018658.1 4680856 4681605 R COG1073 Hydrolases of the alpha/beta superfamily; esterase complement(4680856..4681605) Escherichia coli O104:H4 str. 2011C-3493 13699800 YP_006781195.1 CDS O3K_22695 NC_018658.1 4681787 4682116 D putative biofilm stress and motility protein A 4681787..4682116 Escherichia coli O104:H4 str. 2011C-3493 13699801 YP_006781196.1 CDS O3K_22700 NC_018658.1 4682265 4682540 D hypothetical protein 4682265..4682540 Escherichia coli O104:H4 str. 2011C-3493 13699802 YP_006781197.1 CDS O3K_22705 NC_018658.1 4682657 4684282 R COG1960 Acyl-CoA dehydrogenases; isovaleryl CoA dehydrogenase complement(4682657..4684282) Escherichia coli O104:H4 str. 2011C-3493 13699803 YP_006781198.1 CDS O3K_22710 NC_018658.1 4684366 4685529 R COG0754 Glutathionylspermidine synthase; synthetase/amidase complement(4684366..4685529) Escherichia coli O104:H4 str. 2011C-3493 13699804 YP_006781199.1 CDS O3K_22715 NC_018658.1 4685532 4686170 R hypothetical protein complement(4685532..4686170) Escherichia coli O104:H4 str. 2011C-3493 13699805 YP_006781200.1 CDS O3K_22720 NC_018658.1 4686180 4686413 R COG3766 Predicted membrane protein; inner membrane protein complement(4686180..4686413) Escherichia coli O104:H4 str. 2011C-3493 13699806 YP_006781201.1 CDS O3K_22725 NC_018658.1 4686468 4686578 R COG3766 Predicted membrane protein; inner membrane protein complement(4686468..4686578) Escherichia coli O104:H4 str. 2011C-3493 13699807 YP_006781202.1 CDS O3K_22730 NC_018658.1 4686596 4687255 R hypothetical protein complement(4686596..4687255) Escherichia coli O104:H4 str. 2011C-3493 13699808 YP_006781203.1 CDS O3K_22735 NC_018658.1 4687306 4688004 R COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription; putative transcriptional regulator effector protein complement(4687306..4688004) Escherichia coli O104:H4 str. 2011C-3493 13699809 YP_006781204.1 CDS O3K_22740 NC_018658.1 4688023 4688424 R COG3789 Uncharacterized protein conserved in bacteria; putative cytoplasmic protein complement(4688023..4688424) Escherichia coli O104:H4 str. 2011C-3493 13699810 YP_006781205.1 CDS O3K_22745 NC_018658.1 4688551 4689282 R COG0566 rRNA methylases; 23S rRNA (guanosine-2'-O-)-methyltransferase complement(4688551..4689282) Escherichia coli O104:H4 str. 2011C-3493 13699811 YP_006781206.1 CDS O3K_22750 NC_018658.1 4689462 4691903 R COG0557 Exoribonuclease R; exoribonuclease R complement(4689462..4691903) Escherichia coli O104:H4 str. 2011C-3493 13699812 YP_006781207.1 CDS O3K_22755 NC_018658.1 4691942 4692367 R COG1959 Predicted transcriptional regulator; transcriptional repressor NsrR complement(4691942..4692367) Escherichia coli O104:H4 str. 2011C-3493 13699813 YP_006781208.1 CDS O3K_22760 NC_018658.1 4692572 4693870 R COG0104 Adenylosuccinate synthase; adenylosuccinate synthetase complement(4692572..4693870) Escherichia coli O104:H4 str. 2011C-3493 13699814 YP_006781209.1 CDS O3K_22765 NC_018658.1 4693974 4694171 R COG3242 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4693974..4694171) Escherichia coli O104:H4 str. 2011C-3493 13699815 YP_006781210.1 CDS O3K_22770 NC_018658.1 4694253 4695257 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; FtsH protease regulator HflC complement(4694253..4695257) Escherichia coli O104:H4 str. 2011C-3493 13699816 YP_006781211.1 CDS O3K_22775 NC_018658.1 4695260 4696519 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; FtsH protease regulator HflK complement(4695260..4696519) Escherichia coli O104:H4 str. 2011C-3493 13699817 YP_006781212.1 CDS O3K_22780 NC_018658.1 4696605 4697885 R COG2262 GTPases; GTPase HflX complement(4696605..4697885) Escherichia coli O104:H4 str. 2011C-3493 13699818 YP_006781213.1 CDS hfq NC_018658.1 4697962 4698270 R COG1923 Uncharacterized host factor I protein; RNA-binding protein Hfq complement(4697962..4698270) Escherichia coli O104:H4 str. 2011C-3493 13699819 YP_006781214.1 CDS miaA NC_018658.1 4698356 4699306 R COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA delta(2)-isopentenylpyrophosphate transferase complement(4698356..4699306) Escherichia coli O104:H4 str. 2011C-3493 13699820 YP_006781215.1 CDS mutL NC_018658.1 4699299 4701146 R COG0323 DNA mismatch repair enzyme (predicted ATPase); DNA mismatch repair protein complement(4699299..4701146) Escherichia coli O104:H4 str. 2011C-3493 13699821 YP_006781216.1 CDS O3K_22800 NC_018658.1 4701156 4702493 R COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-l-alanine amidase II complement(4701156..4702493) Escherichia coli O104:H4 str. 2011C-3493 13699822 YP_006781217.1 CDS O3K_22805 NC_018658.1 4702512 4702973 R COG0802 Predicted ATPase or kinase; ADP-binding protein complement(4702512..4702973) Escherichia coli O104:H4 str. 2011C-3493 13699823 YP_006781218.1 CDS O3K_22810 NC_018658.1 4702945 4704492 R COG0062 Uncharacterized conserved protein; putative carbohydrate kinase complement(4702945..4704492) Escherichia coli O104:H4 str. 2011C-3493 13699824 YP_006781219.1 CDS O3K_22815 NC_018658.1 4704491 4705630 D COG1600 Uncharacterized Fe-S protein; Fe-S electron transport protein 4704491..4705630 Escherichia coli O104:H4 str. 2011C-3493 13699825 YP_006781220.1 CDS O3K_22820 NC_018658.1 4706186 4706731 R COG1949 Oligoribonuclease (3'->5' exoribonuclease); oligoribonuclease complement(4706186..4706731) Escherichia coli O104:H4 str. 2011C-3493 13699827 YP_006781221.1 CDS O3K_22825 NC_018658.1 4706826 4707878 D COG1162 Predicted GTPases; GTPase RsgA 4706826..4707878 Escherichia coli O104:H4 str. 2011C-3493 13699828 YP_006781222.1 CDS psd NC_018658.1 4707975 4708943 D COG0688 Phosphatidylserine decarboxylase; phosphatidylserine decarboxylase 4707975..4708943 Escherichia coli O104:H4 str. 2011C-3493 13699829 YP_006781223.1 CDS O3K_22835 NC_018658.1 4708965 4712288 D COG3264 Small-conductance mechanosensitive channel; putative mechanosensitive channel protein 4708965..4712288 Escherichia coli O104:H4 str. 2011C-3493 13699830 YP_006781224.1 CDS O3K_22840 NC_018658.1 4712317 4712631 R hypothetical protein complement(4712317..4712631) Escherichia coli O104:H4 str. 2011C-3493 13699831 YP_006781225.1 CDS O3K_22845 NC_018658.1 4712628 4712942 R hypothetical protein complement(4712628..4712942) Escherichia coli O104:H4 str. 2011C-3493 13699832 YP_006781226.1 CDS O3K_22850 NC_018658.1 4712994 4714496 R COG0531 Amino acid transporters; inner membrane transporter YjeM complement(4712994..4714496) Escherichia coli O104:H4 str. 2011C-3493 13699833 YP_006781227.1 CDS O3K_22855 NC_018658.1 4714715 4715692 R COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II); poxB regulator PoxA complement(4714715..4715692) Escherichia coli O104:H4 str. 2011C-3493 13699834 YP_006781228.1 CDS O3K_22860 NC_018658.1 4716017 4717825 D COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; fumarate reductase flavoprotein subunit 4716017..4717825 Escherichia coli O104:H4 str. 2011C-3493 13699835 YP_006781229.1 CDS O3K_22865 NC_018658.1 4717818 4718552 D COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; fumarate reductase iron-sulfur subunit 4717818..4718552 Escherichia coli O104:H4 str. 2011C-3493 13699836 YP_006781230.1 CDS O3K_22870 NC_018658.1 4718563 4718958 D COG3029 Fumarate reductase subunit C; fumarate reductase subunit C 4718563..4718958 Escherichia coli O104:H4 str. 2011C-3493 13699837 YP_006781231.1 CDS O3K_22875 NC_018658.1 4718969 4719328 D COG3080 Fumarate reductase subunit D; fumarate reductase subunit D 4718969..4719328 Escherichia coli O104:H4 str. 2011C-3493 13699838 YP_006781232.1 CDS ampC NC_018658.1 4719391 4720524 D COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase/D-alanine carboxypeptidase 4719391..4720524 Escherichia coli O104:H4 str. 2011C-3493 13699839 YP_006781233.1 CDS O3K_22885 NC_018658.1 4720613 4721146 D COG3040 Bacterial lipocalin; outer membrane lipoprotein Blc 4720613..4721146 Escherichia coli O104:H4 str. 2011C-3493 13699840 YP_006781234.1 CDS O3K_22890 NC_018658.1 4721143 4721460 R COG2076 Membrane transporters of cations and cationic drugs; suppresser of groEL complement(4721143..4721460) Escherichia coli O104:H4 str. 2011C-3493 13699841 YP_006781235.1 CDS O3K_22895 NC_018658.1 4721635 4721781 R COG5510 Predicted small secreted protein; entericidin B membrane lipoprotein complement(4721635..4721781) Escherichia coli O104:H4 str. 2011C-3493 13699842 YP_006781236.1 CDS O3K_22900 NC_018658.1 4721892 4722017 R entericidin A complement(4721892..4722017) Escherichia coli O104:H4 str. 2011C-3493 13699843 YP_006781237.1 CDS O3K_22905 NC_018658.1 4722069 4722635 R COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); elongation factor P complement(4722069..4722635) Escherichia coli O104:H4 str. 2011C-3493 13699844 YP_006781238.1 CDS O3K_22910 NC_018658.1 4722677 4723705 D COG1509 Lysine 2,3-aminomutase; putative lysine aminomutase 4722677..4723705 Escherichia coli O104:H4 str. 2011C-3493 13699845 YP_006781239.1 CDS O3K_22915 NC_018658.1 4724095 4724964 D COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase); hypothetical protein 4724095..4724964 Escherichia coli O104:H4 str. 2011C-3493 13699846 YP_006781240.1 CDS O3K_22920 NC_018658.1 4725167 4725520 R hypothetical protein complement(4725167..4725520) Escherichia coli O104:H4 str. 2011C-3493 13699847 YP_006781241.1 CDS groEL NC_018658.1 4725658 4727304 R COG0459 Chaperonin GroEL (HSP60 family); chaperonin GroEL complement(4725658..4727304) Escherichia coli O104:H4 str. 2011C-3493 13699848 YP_006781242.1 CDS groES NC_018658.1 4727348 4727641 R COG0234 Co-chaperonin GroES (HSP10); co-chaperonin GroES complement(4727348..4727641) Escherichia coli O104:H4 str. 2011C-3493 13699849 YP_006781243.1 CDS O3K_22935 NC_018658.1 4727917 4729173 D COG0531 Amino acid transporters; transporter 4727917..4729173 Escherichia coli O104:H4 str. 2011C-3493 13699850 YP_006781244.1 CDS fxsA NC_018658.1 4729189 4729665 R COG3030 Protein affecting phage T7 exclusion by the F plasmid; phage T7 F exclusion suppressor FxsA complement(4729189..4729665) Escherichia coli O104:H4 str. 2011C-3493 13699851 YP_006781245.1 CDS aspA NC_018658.1 4730002 4731438 D COG1027 Aspartate ammonia-lyase; aspartate ammonia-lyase 4730002..4731438 Escherichia coli O104:H4 str. 2011C-3493 13699852 YP_006781246.1 CDS O3K_22950 NC_018658.1 4731556 4732857 D COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 4731556..4732857 Escherichia coli O104:H4 str. 2011C-3493 13699853 YP_006781247.1 CDS O3K_22955 NC_018658.1 4732973 4733311 D COG1324 Uncharacterized protein involved in tolerance to divalent cations; divalent-cation tolerance protein CutA 4732973..4733311 Escherichia coli O104:H4 str. 2011C-3493 13699854 YP_006781248.1 CDS dipZ NC_018658.1 4733287 4734984 D COG4232 Thiol:disulfide interchange protein; thiol:disulfide interchange protein 4733287..4734984 Escherichia coli O104:H4 str. 2011C-3493 13699855 YP_006781249.1 CDS O3K_22965 NC_018658.1 4735021 4735596 D COG1309 Transcriptional regulator; transcriptional regulator 4735021..4735596 Escherichia coli O104:H4 str. 2011C-3493 13699856 YP_006781250.1 CDS O3K_22970 NC_018658.1 4735976 4737238 D COG0582 Integrase; Prophage integrase 4735976..4737238 Escherichia coli O104:H4 str. 2011C-3493 13699858 YP_006781251.1 CDS O3K_22985 NC_018658.1 4741547 4741912 D COG3547 Transposase and inactivated derivatives; hypothetical protein 4741547..4741912 Escherichia coli O104:H4 str. 2011C-3493 13699859 YP_006781252.1 CDS O3K_22990 NC_018658.1 4741909 4742163 R COG3436 Transposase and inactivated derivatives; truncated transposase complement(4741909..4742163) Escherichia coli O104:H4 str. 2011C-3493 13699860 YP_006781253.1 CDS O3K_22995 NC_018658.1 4742241 4742489 R hypothetical protein complement(4742241..4742489) Escherichia coli O104:H4 str. 2011C-3493 13699861 YP_006781254.1 CDS O3K_23000 NC_018658.1 4742556 4743317 D hypothetical protein 4742556..4743317 Escherichia coli O104:H4 str. 2011C-3493 13699862 YP_006781255.1 CDS O3K_23005 NC_018658.1 4743678 4747535 D COG3468 Type V secretory pathway, adhesin AidA; Serine protease pet precursor (Plasmid-encoded toxin pet) 4743678..4747535 Escherichia coli O104:H4 str. 2011C-3493 13699863 YP_006781256.1 CDS O3K_23010 NC_018658.1 4747582 4748163 D hypothetical protein 4747582..4748163 Escherichia coli O104:H4 str. 2011C-3493 13699864 YP_006781257.1 CDS O3K_23015 NC_018658.1 4748355 4749758 R COG3436 Transposase and inactivated derivatives; transposase complement(4748355..4749758) Escherichia coli O104:H4 str. 2011C-3493 13699865 YP_006781258.1 CDS O3K_23020 NC_018658.1 4749857 4750264 R COG3436 Transposase and inactivated derivatives; protein encoded within IS complement(4749857..4750264) Escherichia coli O104:H4 str. 2011C-3493 13699866 YP_006781259.1 CDS O3K_23025 NC_018658.1 4750330 4750833 D COG3464 Transposase and inactivated derivatives; transposase 4750330..4750833 Escherichia coli O104:H4 str. 2011C-3493 13699867 YP_006781260.1 CDS O3K_23035 NC_018658.1 4752062 4752487 D COG2963 Transposase and inactivated derivatives; transposase OrfA from plasmid origin 4752062..4752487 Escherichia coli O104:H4 str. 2011C-3493 13699868 YP_006781261.1 CDS O3K_23040 NC_018658.1 4752484 4752735 D COG3436 Transposase and inactivated derivatives; IS66 transposase 4752484..4752735 Escherichia coli O104:H4 str. 2011C-3493 13699869 YP_006781262.1 CDS O3K_23045 NC_018658.1 4752761 4753087 D COG2963 Transposase and inactivated derivatives; IS629 orfA 4752761..4753087 Escherichia coli O104:H4 str. 2011C-3493 13699870 YP_006781263.1 CDS O3K_23055 NC_018658.1 4754157 4755680 D COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid 4754157..4755680 Escherichia coli O104:H4 str. 2011C-3493 13699871 YP_006781264.1 CDS O3K_23065 NC_018658.1 4756645 4758840 R COG1629 Outer membrane receptor proteins, mostly Fe transport; Ferric aerobactin receptor complement(4756645..4758840) Escherichia coli O104:H4 str. 2011C-3493 13699872 YP_006781265.1 CDS O3K_23070 NC_018658.1 4758846 4760183 R COG3486 Lysine/ornithine N-monooxygenase; L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase) complement(4758846..4760183) Escherichia coli O104:H4 str. 2011C-3493 13699873 YP_006781266.1 CDS O3K_23075 NC_018658.1 4760180 4761922 R COG4264 Siderophore synthetase component; Aerobactin siderophore biosynthesis protein complement(4760180..4761922) Escherichia coli O104:H4 str. 2011C-3493 13699874 YP_006781267.1 CDS O3K_23080 NC_018658.1 4761922 4762869 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; siderophore biosynthesis protein complement(4761922..4762869) Escherichia coli O104:H4 str. 2011C-3493 13699875 YP_006781268.1 CDS O3K_23085 NC_018658.1 4762870 4764651 R COG4264 Siderophore synthetase component; aerobactin siderophore biosynthesis protein complement(4762870..4764651) Escherichia coli O104:H4 str. 2011C-3493 13699876 YP_006781269.1 CDS O3K_23090 NC_018658.1 4764730 4765923 D COG0477 Permeases of the major facilitator superfamily; membrane transport protein, major facilitator superfamily 4764730..4765923 Escherichia coli O104:H4 str. 2011C-3493 13699877 YP_006781270.1 CDS O3K_23095 NC_018658.1 4767136 4767303 D hypothetical protein 4767136..4767303 Escherichia coli O104:H4 str. 2011C-3493 13699878 YP_006781271.1 CDS O3K_23100 NC_018658.1 4767290 4767475 R COG3436 Transposase and inactivated derivatives; transposase complement(4767290..4767475) Escherichia coli O104:H4 str. 2011C-3493 13699879 YP_006781272.1 CDS O3K_23105 NC_018658.1 4767539 4768579 D COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 4767539..4768579 Escherichia coli O104:H4 str. 2011C-3493 13699880 YP_006781273.1 CDS O3K_23115 NC_018658.1 4769094 4769621 D hypothetical protein 4769094..4769621 Escherichia coli O104:H4 str. 2011C-3493 13699881 YP_006781274.1 CDS O3K_23120 NC_018658.1 4769978 4770331 R COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF1, IS66 family protein complement(4769978..4770331) Escherichia coli O104:H4 str. 2011C-3493 13699882 YP_006781275.1 CDS O3K_23125 NC_018658.1 4770396 4771520 R COG4584 Transposase and inactivated derivatives; transposase complement(4770396..4771520) Escherichia coli O104:H4 str. 2011C-3493 13699883 YP_006781276.1 CDS O3K_23130 NC_018658.1 4771741 4772250 D COG3436 Transposase and inactivated derivatives; hypothetical protein 4771741..4772250 Escherichia coli O104:H4 str. 2011C-3493 13699884 YP_006781277.1 CDS O3K_23135 NC_018658.1 4772313 4772531 D COG3328 Transposase and inactivated derivatives; transposase 4772313..4772531 Escherichia coli O104:H4 str. 2011C-3493 13699885 YP_006781278.1 CDS O3K_23140 NC_018658.1 4772682 4776800 R COG3468 Type V secretory pathway, adhesin AidA; Serine protease pic precursor (ShMu) complement(4772682..4776800) Escherichia coli O104:H4 str. 2011C-3493 13699886 YP_006781279.1 CDS O3K_23145 NC_018658.1 4776965 4777351 R COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase complement(4776965..4777351) Escherichia coli O104:H4 str. 2011C-3493 13699887 YP_006781280.1 CDS O3K_23150 NC_018658.1 4777528 4779051 R COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid complement(4777528..4779051) Escherichia coli O104:H4 str. 2011C-3493 13699888 YP_006781281.1 CDS O3K_23160 NC_018658.1 4780122 4780448 R COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein complement(4780122..4780448) Escherichia coli O104:H4 str. 2011C-3493 13699889 YP_006781282.1 CDS O3K_23165 NC_018658.1 4780972 4781445 D antirestriction protein 4780972..4781445 Escherichia coli O104:H4 str. 2011C-3493 13699890 YP_006781283.1 CDS O3K_23170 NC_018658.1 4781461 4781937 D COG2003 DNA repair proteins; RADC family DNA repair protein 4781461..4781937 Escherichia coli O104:H4 str. 2011C-3493 13699891 YP_006781284.1 CDS O3K_23175 NC_018658.1 4782024 4782245 D hypothetical protein 4782024..4782245 Escherichia coli O104:H4 str. 2011C-3493 13699892 YP_006781285.1 CDS O3K_23180 NC_018658.1 4782325 4782702 D antitoxin of the YeeV-YeeU toxin-antitoxin system, CP4-44 prophage 4782325..4782702 Escherichia coli O104:H4 str. 2011C-3493 13699893 YP_006781286.1 CDS O3K_23185 NC_018658.1 4782749 4783126 D hypothetical protein 4782749..4783126 Escherichia coli O104:H4 str. 2011C-3493 13699894 YP_006781287.1 CDS O3K_23190 NC_018658.1 4783123 4783611 D hypothetical protein 4783123..4783611 Escherichia coli O104:H4 str. 2011C-3493 13699895 YP_006781288.1 CDS O3K_23195 NC_018658.1 4783631 4783828 D hypothetical protein 4783631..4783828 Escherichia coli O104:H4 str. 2011C-3493 13699896 YP_006781289.1 CDS O3K_23200 NC_018658.1 4783913 4784755 D hypothetical protein 4783913..4784755 Escherichia coli O104:H4 str. 2011C-3493 13699897 YP_006781290.1 CDS O3K_23205 NC_018658.1 4785504 4787042 D COG3710 DNA-binding winged-HTH domains; DNA-binding transcriptional activator CadC 4785504..4787042 Escherichia coli O104:H4 str. 2011C-3493 13699898 YP_006781291.1 CDS cadB NC_018658.1 4787408 4788742 D COG0531 Amino acid transporters; lysine/cadaverine antiporter 4787408..4788742 Escherichia coli O104:H4 str. 2011C-3493 13699899 YP_006781292.1 CDS O3K_23215 NC_018658.1 4788822 4790969 D COG1982 Arginine/lysine/ornithine decarboxylases; lysine decarboxylase CadA 4788822..4790969 Escherichia coli O104:H4 str. 2011C-3493 13699900 YP_006781293.1 CDS O3K_23220 NC_018658.1 4791028 4792485 D COG3104 Dipeptide/tripeptide permease; transporter 4791028..4792485 Escherichia coli O104:H4 str. 2011C-3493 13699901 YP_006781294.1 CDS O3K_23225 NC_018658.1 4792722 4794239 D COG1190 Lysyl-tRNA synthetase (class II); lysyl-tRNA synthetase 4792722..4794239 Escherichia coli O104:H4 str. 2011C-3493 13699902 YP_006781295.1 CDS O3K_23230 NC_018658.1 4794358 4794531 R hypothetical protein complement(4794358..4794531) Escherichia coli O104:H4 str. 2011C-3493 13699903 YP_006781296.1 CDS O3K_23235 NC_018658.1 4794559 4794855 R hypothetical protein complement(4794559..4794855) Escherichia coli O104:H4 str. 2011C-3493 13699904 YP_006781297.1 CDS O3K_23240 NC_018658.1 4795082 4795354 R COG2388 Predicted acetyltransferase; putative acyltransferase complement(4795082..4795354) Escherichia coli O104:H4 str. 2011C-3493 13699905 YP_006781298.1 CDS O3K_23245 NC_018658.1 4795366 4795596 R COG3592 Uncharacterized conserved protein; hypothetical protein complement(4795366..4795596) Escherichia coli O104:H4 str. 2011C-3493 13699906 YP_006781299.1 CDS O3K_23250 NC_018658.1 4795777 4797408 D COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; sensory histidine kinase DcuS 4795777..4797408 Escherichia coli O104:H4 str. 2011C-3493 13699907 YP_006781300.1 CDS O3K_23255 NC_018658.1 4797405 4798124 D COG4565 Response regulator of citrate/malate metabolism; DNA-binding transcriptional activator DcuR 4797405..4798124 Escherichia coli O104:H4 str. 2011C-3493 13699908 YP_006781301.1 CDS O3K_23260 NC_018658.1 4798695 4800035 D COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 4798695..4800035 Escherichia coli O104:H4 str. 2011C-3493 13699909 YP_006781302.1 CDS O3K_23265 NC_018658.1 4800113 4801759 D COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase FumB 4800113..4801759 Escherichia coli O104:H4 str. 2011C-3493 13699910 YP_006781303.1 CDS O3K_23270 NC_018658.1 4801882 4802511 D COG3647 Predicted membrane protein; hypothetical protein 4801882..4802511 Escherichia coli O104:H4 str. 2011C-3493 13699911 YP_006781304.1 CDS O3K_23275 NC_018658.1 4802650 4804059 R COG2211 Na+/melibiose symporter and related transporters; melibiose:sodium symporter complement(4802650..4804059) Escherichia coli O104:H4 str. 2011C-3493 13699912 YP_006781305.1 CDS O3K_23280 NC_018658.1 4804174 4805529 R COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; alpha-galactosidase complement(4804174..4805529) Escherichia coli O104:H4 str. 2011C-3493 13699913 YP_006781306.1 CDS O3K_23285 NC_018658.1 4805812 4806720 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator MelR 4805812..4806720 Escherichia coli O104:H4 str. 2011C-3493 13699914 YP_006781307.1 CDS O3K_23290 NC_018658.1 4806916 4809186 D COG1982 Arginine/lysine/ornithine decarboxylases; arginine decarboxylase 4806916..4809186 Escherichia coli O104:H4 str. 2011C-3493 13699915 YP_006781308.1 CDS O3K_23295 NC_018658.1 4809511 4810272 D COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 4809511..4810272 Escherichia coli O104:H4 str. 2011C-3493 13699916 YP_006781309.1 CDS O3K_23300 NC_018658.1 4810409 4811746 D COG0531 Amino acid transporters; arginine:agmatin antiporter 4810409..4811746 Escherichia coli O104:H4 str. 2011C-3493 13699917 YP_006781310.1 CDS O3K_23305 NC_018658.1 4811850 4813493 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; putative metal dependent hydrolase 4811850..4813493 Escherichia coli O104:H4 str. 2011C-3493 13699918 YP_006781311.1 CDS O3K_23310 NC_018658.1 4813490 4814158 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator BasR 4813490..4814158 Escherichia coli O104:H4 str. 2011C-3493 13699919 YP_006781312.1 CDS O3K_23315 NC_018658.1 4814168 4815259 D COG0642 Signal transduction histidine kinase; sensor protein BasS/PmrB 4814168..4815259 Escherichia coli O104:H4 str. 2011C-3493 13699920 YP_006781313.1 CDS O3K_23320 NC_018658.1 4815436 4816938 R COG0477 Permeases of the major facilitator superfamily; proline/glycine betaine transporter complement(4815436..4816938) Escherichia coli O104:H4 str. 2011C-3493 13699921 YP_006781314.1 CDS O3K_23325 NC_018658.1 4817202 4818080 R hypothetical protein complement(4817202..4818080) Escherichia coli O104:H4 str. 2011C-3493 13699922 YP_006781315.1 CDS O3K_23330 NC_018658.1 4818077 4820305 R COG0699 Predicted GTPases (dynamin-related); hypothetical protein complement(4818077..4820305) Escherichia coli O104:H4 str. 2011C-3493 13699923 YP_006781316.1 CDS O3K_23335 NC_018658.1 4820707 4821042 D COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; putative alkylphosphonate uptake protein in phosphonate metabolism 4820707..4821042 Escherichia coli O104:H4 str. 2011C-3493 13699924 YP_006781317.1 CDS O3K_23340 NC_018658.1 4821202 4821645 D COG2764 Uncharacterized protein conserved in bacteria; hypothetical protein 4821202..4821645 Escherichia coli O104:H4 str. 2011C-3493 13699925 YP_006781318.1 CDS O3K_23345 NC_018658.1 4821778 4822566 D COG3638 ABC-type phosphate/phosphonate transport system, ATPase component; phosphonate/organophosphate ester transporter subunit 4821778..4822566 Escherichia coli O104:H4 str. 2011C-3493 13699926 YP_006781319.1 CDS O3K_23350 NC_018658.1 4822591 4823607 D COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component; phosphonate/organophosphate ester transporter subunit PhnD 4822591..4823607 Escherichia coli O104:H4 str. 2011C-3493 13699927 YP_006781320.1 CDS O3K_23355 NC_018658.1 4823713 4824492 D COG3639 ABC-type phosphate/phosphonate transport system, permease component; Pn transporter membrane channel protein 4823713..4824492 Escherichia coli O104:H4 str. 2011C-3493 13699928 YP_006781321.1 CDS O3K_23360 NC_018658.1 4824513 4825238 D COG2188 Transcriptional regulators; phosphonate metabolism transcriptional regulator PhnF 4824513..4825238 Escherichia coli O104:H4 str. 2011C-3493 13699929 YP_006781322.1 CDS O3K_23365 NC_018658.1 4825239 4825691 D COG3624 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4825239..4825691 Escherichia coli O104:H4 str. 2011C-3493 13699930 YP_006781323.1 CDS phnH NC_018658.1 4825688 4826272 D COG3625 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4825688..4826272 Escherichia coli O104:H4 str. 2011C-3493 13699931 YP_006781324.1 CDS O3K_23375 NC_018658.1 4826272 4827336 D COG3626 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4826272..4827336 Escherichia coli O104:H4 str. 2011C-3493 13699932 YP_006781325.1 CDS O3K_23380 NC_018658.1 4827329 4828174 D COG3627 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit PhnJ 4827329..4828174 Escherichia coli O104:H4 str. 2011C-3493 13699933 YP_006781326.1 CDS phnK NC_018658.1 4828171 4828929 D COG4107 ABC-type phosphonate transport system, ATPase component; phosphonate C-P lyase system protein PhnK 4828171..4828929 Escherichia coli O104:H4 str. 2011C-3493 13699934 YP_006781327.1 CDS O3K_23390 NC_018658.1 4829106 4829786 D COG4778 ABC-type phosphonate transport system, ATPase component; carbon-phosphorus lyase complex subunit PhnL 4829106..4829786 Escherichia coli O104:H4 str. 2011C-3493 13699935 YP_006781328.1 CDS O3K_23395 NC_018658.1 4829783 4830919 D COG3454 Metal-dependent hydrolase involved in phosphonate metabolism; phosphonate metabolism protein PhnM 4829783..4830919 Escherichia coli O104:H4 str. 2011C-3493 13699936 YP_006781329.1 CDS O3K_23400 NC_018658.1 4830919 4831476 D COG3709 Uncharacterized component of phosphonate metabolism; ribose 1,5-bisphosphokinase 4830919..4831476 Escherichia coli O104:H4 str. 2011C-3493 13699937 YP_006781330.1 CDS O3K_23405 NC_018658.1 4831463 4831897 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; aminoalkylphosphonic acid N-acetyltransferase 4831463..4831897 Escherichia coli O104:H4 str. 2011C-3493 13699938 YP_006781331.1 CDS phnP NC_018658.1 4831899 4832657 D COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; carbon-phosphorus lyase complex accessory protein 4831899..4832657 Escherichia coli O104:H4 str. 2011C-3493 13699939 YP_006781332.1 CDS O3K_23415 NC_018658.1 4832804 4833133 R hypothetical protein complement(4832804..4833133) Escherichia coli O104:H4 str. 2011C-3493 13699940 YP_006781333.1 CDS O3K_23420 NC_018658.1 4833202 4833519 R COG0698 Ribose 5-phosphate isomerase RpiB; hypothetical protein complement(4833202..4833519) Escherichia coli O104:H4 str. 2011C-3493 13699941 YP_006781334.1 CDS O3K_23425 NC_018658.1 4833772 4835757 D COG2015 Alkyl sulfatase and related hydrolases; hypothetical protein 4833772..4835757 Escherichia coli O104:H4 str. 2011C-3493 13699942 YP_006781335.1 CDS O3K_23430 NC_018658.1 4835966 4836241 D formate dehydrogenase H 4835966..4836241 Escherichia coli O104:H4 str. 2011C-3493 13699943 YP_006781336.1 CDS O3K_23435 NC_018658.1 4836260 4837291 D COG1566 Multidrug resistance efflux pump; multidrug resistance protein MdtN 4836260..4837291 Escherichia coli O104:H4 str. 2011C-3493 13699944 YP_006781337.1 CDS O3K_23440 NC_018658.1 4837291 4839342 D COG1289 Predicted membrane protein; multidrug efflux system protein MdtO 4837291..4839342 Escherichia coli O104:H4 str. 2011C-3493 13699945 YP_006781338.1 CDS O3K_23445 NC_018658.1 4839339 4840805 D COG1538 Outer membrane protein; putative outer membrane efflux protein MdtP 4839339..4840805 Escherichia coli O104:H4 str. 2011C-3493 13699946 YP_006781339.1 CDS O3K_23450 NC_018658.1 4841003 4841422 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-H, selenopolypeptide subunit 4841003..4841422 Escherichia coli O104:H4 str. 2011C-3493 13699947 YP_006781340.1 CDS O3K_23455 NC_018658.1 4841471 4843150 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-H, selenopolypeptide subunit 4841471..4843150 Escherichia coli O104:H4 str. 2011C-3493 13699948 YP_006781341.1 CDS O3K_23460 NC_018658.1 4843244 4843933 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 4843244..4843933 Escherichia coli O104:H4 str. 2011C-3493 13699949 YP_006781342.1 CDS gltP NC_018658.1 4844011 4845324 R COG1301 Na+/H+-dicarboxylate symporters; glutamate/aspartate:proton symporter complement(4844011..4845324) Escherichia coli O104:H4 str. 2011C-3493 13699950 YP_006781343.1 CDS O3K_23470 NC_018658.1 4845666 4846262 R COG4235 Cytochrome c biogenesis factor; formate-dependent nitrite reductase complex subunit NrfG complement(4845666..4846262) Escherichia coli O104:H4 str. 2011C-3493 13699951 YP_006781344.1 CDS O3K_23475 NC_018658.1 4846259 4846642 R COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; formate-dependent nitrite reductase complex subunit NrfF complement(4846259..4846642) Escherichia coli O104:H4 str. 2011C-3493 13699952 YP_006781345.1 CDS O3K_23480 NC_018658.1 4846635 4848293 R COG1138 Cytochrome c biogenesis factor; heme lyase subunit NrfE complement(4846635..4848293) Escherichia coli O104:H4 str. 2011C-3493 13699953 YP_006781346.1 CDS O3K_23485 NC_018658.1 4848373 4849329 R COG3301 Formate-dependent nitrite reductase, membrane component; formate-dependent nitrite reductase, membrane subunit complement(4848373..4849329) Escherichia coli O104:H4 str. 2011C-3493 13699954 YP_006781347.1 CDS O3K_23490 NC_018658.1 4849326 4849997 R COG0437 Fe-S-cluster-containing hydrogenase components 1; formate-dependent nitrite reductase, Fe-S center complement(4849326..4849997) Escherichia coli O104:H4 str. 2011C-3493 13699955 YP_006781348.1 CDS O3K_23495 NC_018658.1 4849994 4850560 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; cytochrome c nitrite reductase pentaheme subunit complement(4849994..4850560) Escherichia coli O104:H4 str. 2011C-3493 13699956 YP_006781349.1 CDS nrfA NC_018658.1 4850605 4852041 R COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit; cytochrome c nitrite reductase subunit c552 complement(4850605..4852041) Escherichia coli O104:H4 str. 2011C-3493 13699957 YP_006781350.1 CDS O3K_23505 NC_018658.1 4852433 4854391 D COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; acetyl-CoA synthetase 4852433..4854391 Escherichia coli O104:H4 str. 2011C-3493 13699958 YP_006781351.1 CDS O3K_23510 NC_018658.1 4854591 4854905 D COG3162 Predicted membrane protein; hypothetical protein 4854591..4854905 Escherichia coli O104:H4 str. 2011C-3493 13699959 YP_006781352.1 CDS actP NC_018658.1 4854902 4856551 D COG4147 Predicted symporter; acetate permease 4854902..4856551 Escherichia coli O104:H4 str. 2011C-3493 13699960 YP_006781353.1 CDS O3K_23520 NC_018658.1 4856729 4858021 D COG1357 Uncharacterized low-complexity proteins; hypothetical protein 4856729..4858021 Escherichia coli O104:H4 str. 2011C-3493 13699961 YP_006781354.1 CDS O3K_23525 NC_018658.1 4858175 4859824 R COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; putative cation/proton antiporter complement(4858175..4859824) Escherichia coli O104:H4 str. 2011C-3493 13699962 YP_006781355.1 CDS O3K_23530 NC_018658.1 4859975 4861324 R COG2252 Permeases; permease complement(4859975..4861324) Escherichia coli O104:H4 str. 2011C-3493 13699963 YP_006781356.1 CDS O3K_23535 NC_018658.1 4861870 4862334 R COG0789 Predicted transcriptional regulators; redox-sensitivie transcriptional activator Soxr complement(4861870..4862334) Escherichia coli O104:H4 str. 2011C-3493 13699964 YP_006781357.1 CDS O3K_23540 NC_018658.1 4862420 4862743 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator SoxS 4862420..4862743 Escherichia coli O104:H4 str. 2011C-3493 13699965 YP_006781358.1 CDS O3K_23545 NC_018658.1 4862746 4864332 R COG4943 Predicted signal transduction protein containing sensor and EAL domains; signal transduction protein (EAL domain containing protein) complement(4862746..4864332) Escherichia coli O104:H4 str. 2011C-3493 13699966 YP_006781359.1 CDS O3K_23550 NC_018658.1 4864762 4865043 D hypothetical protein 4864762..4865043 Escherichia coli O104:H4 str. 2011C-3493 13699967 YP_006781360.1 CDS O3K_23555 NC_018658.1 4865142 4865678 R COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein complement(4865142..4865678) Escherichia coli O104:H4 str. 2011C-3493 13699968 YP_006781361.1 CDS uvrA NC_018658.1 4865932 4868754 D COG0178 Excinuclease ATPase subunit; excinuclease ABC subunit A 4865932..4868754 Escherichia coli O104:H4 str. 2011C-3493 13699969 YP_006781362.1 CDS O3K_23565 NC_018658.1 4868789 4869145 R COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4868789..4869145) Escherichia coli O104:H4 str. 2011C-3493 13699970 YP_006781363.1 CDS O3K_23570 NC_018658.1 4869149 4869565 R COG0432 Uncharacterized conserved protein; hypothetical protein complement(4869149..4869565) Escherichia coli O104:H4 str. 2011C-3493 13699971 YP_006781364.1 CDS aphA NC_018658.1 4869676 4870389 R COG3700 Acid phosphatase (class B); acid phosphatase/phosphotransferase complement(4869676..4870389) Escherichia coli O104:H4 str. 2011C-3493 13699972 YP_006781365.1 CDS O3K_23580 NC_018658.1 4870791 4871294 D hypothetical protein 4870791..4871294 Escherichia coli O104:H4 str. 2011C-3493 13699973 YP_006781366.1 CDS O3K_23585 NC_018658.1 4871516 4872709 R COG1448 Aspartate/tyrosine/aromatic aminotransferase; aromatic amino acid aminotransferase complement(4871516..4872709) Escherichia coli O104:H4 str. 2011C-3493 13699974 YP_006781367.1 CDS alr NC_018658.1 4872962 4874041 R COG0787 Alanine racemase; alanine racemase complement(4872962..4874041) Escherichia coli O104:H4 str. 2011C-3493 13699975 YP_006781368.1 CDS O3K_23595 NC_018658.1 4874094 4875509 R COG0305 Replicative DNA helicase; replicative DNA helicase complement(4874094..4875509) Escherichia coli O104:H4 str. 2011C-3493 13699976 YP_006781369.1 CDS O3K_23600 NC_018658.1 4875592 4876575 D COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; quinone oxidoreductase 4875592..4876575 Escherichia coli O104:H4 str. 2011C-3493 13699977 YP_006781370.1 CDS pspG NC_018658.1 4876741 4876983 R phage shock protein G complement(4876741..4876983) Escherichia coli O104:H4 str. 2011C-3493 13699978 YP_006781371.1 CDS O3K_23610 NC_018658.1 4877117 4878136 R COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase A complement(4877117..4878136) Escherichia coli O104:H4 str. 2011C-3493 13699979 YP_006781372.1 CDS O3K_23615 NC_018658.1 4878518 4879231 R hypothetical protein complement(4878518..4879231) Escherichia coli O104:H4 str. 2011C-3493 13699980 YP_006781373.1 CDS O3K_23620 NC_018658.1 4879255 4879509 R hypothetical protein complement(4879255..4879509) Escherichia coli O104:H4 str. 2011C-3493 13699981 YP_006781374.1 CDS O3K_23625 NC_018658.1 4879827 4880342 D COG0735 Fe2+/Zn2+ uptake regulation proteins; zinc uptake transcriptional repressor 4879827..4880342 Escherichia coli O104:H4 str. 2011C-3493 13699982 YP_006781375.1 CDS O3K_23630 NC_018658.1 4880384 4880593 R COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4880384..4880593) Escherichia coli O104:H4 str. 2011C-3493 13699983 YP_006781376.1 CDS O3K_23635 NC_018658.1 4880689 4882035 R COG0534 Na+-driven multidrug efflux pump; DNA-damage-inducible SOS response protein complement(4880689..4882035) Escherichia coli O104:H4 str. 2011C-3493 13699984 YP_006781377.1 CDS O3K_23640 NC_018658.1 4882108 4882716 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); LexA repressor complement(4882108..4882716) Escherichia coli O104:H4 str. 2011C-3493 13699985 YP_006781378.1 CDS O3K_23645 NC_018658.1 4882826 4883194 R COG0818 Diacylglycerol kinase; diacylglycerol kinase complement(4882826..4883194) Escherichia coli O104:H4 str. 2011C-3493 13699986 YP_006781379.1 CDS O3K_23650 NC_018658.1 4883365 4885788 D COG2937 Glycerol-3-phosphate O-acyltransferase; glycerol-3-phosphate acyltransferase 4883365..4885788 Escherichia coli O104:H4 str. 2011C-3493 13699987 YP_006781380.1 CDS ubiA NC_018658.1 4885943 4886815 R COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; 4-hydroxybenzoate octaprenyltransferase complement(4885943..4886815) Escherichia coli O104:H4 str. 2011C-3493 13699988 YP_006781381.1 CDS ubiC NC_018658.1 4886828 4887325 R COG3161 4-hydroxybenzoate synthetase (chorismate lyase); chorismate pyruvate lyase complement(4886828..4887325) Escherichia coli O104:H4 str. 2011C-3493 13699989 YP_006781382.1 CDS O3K_23665 NC_018658.1 4887548 4888876 R COG1357 Uncharacterized low-complexity proteins; hypothetical protein complement(4887548..4888876) Escherichia coli O104:H4 str. 2011C-3493 13699990 YP_006781383.1 CDS O3K_23670 NC_018658.1 4888934 4889128 R hypothetical protein complement(4888934..4889128) Escherichia coli O104:H4 str. 2011C-3493 13699991 YP_006781384.1 CDS O3K_23675 NC_018658.1 4889357 4890277 R maltose regulon periplasmic protein complement(4889357..4890277) Escherichia coli O104:H4 str. 2011C-3493 13699992 YP_006781385.1 CDS lamB NC_018658.1 4890429 4891769 R COG4580 Maltoporin (phage lambda and maltose receptor); maltoporin complement(4890429..4891769) Escherichia coli O104:H4 str. 2011C-3493 13699993 YP_006781386.1 CDS O3K_23685 NC_018658.1 4891841 4892956 R COG3839 ABC-type sugar transport systems, ATPase components; maltose/maltodextrin transporter ATP-binding protein complement(4891841..4892956) Escherichia coli O104:H4 str. 2011C-3493 13699994 YP_006781387.1 CDS O3K_23690 NC_018658.1 4893133 4893228 D hypothetical protein 4893133..4893228 Escherichia coli O104:H4 str. 2011C-3493 13699995 YP_006781388.1 CDS malE NC_018658.1 4893321 4894511 D COG2182 Maltose-binding periplasmic proteins/domains; maltose ABC transporter substrate-binding protein 4893321..4894511 Escherichia coli O104:H4 str. 2011C-3493 13699996 YP_006781389.1 CDS malF NC_018658.1 4894665 4896209 D COG1175 ABC-type sugar transport systems, permease components; maltose transporter membrane protein 4894665..4896209 Escherichia coli O104:H4 str. 2011C-3493 13699997 YP_006781390.1 CDS malG NC_018658.1 4896224 4897114 D COG3833 ABC-type maltose transport systems, permease component; maltose transporter permease 4896224..4897114 Escherichia coli O104:H4 str. 2011C-3493 13699998 YP_006781391.1 CDS xylE NC_018658.1 4897486 4898961 D COG0477 Permeases of the major facilitator superfamily; D-xylose transporter XylE 4897486..4898961 Escherichia coli O104:H4 str. 2011C-3493 13699999 YP_006781392.1 CDS O3K_23715 NC_018658.1 4899005 4899415 R COG3223 Predicted membrane protein; phosphate-starvation-inducible protein PsiE complement(4899005..4899415) Escherichia coli O104:H4 str. 2011C-3493 13700000 YP_006781393.1 CDS O3K_23720 NC_018658.1 4899541 4899684 R hypothetical protein complement(4899541..4899684) Escherichia coli O104:H4 str. 2011C-3493 13700001 YP_006781394.1 CDS O3K_23725 NC_018658.1 4900010 4902106 R porin complement(4900010..4902106) Escherichia coli O104:H4 str. 2011C-3493 13700002 YP_006781395.1 CDS O3K_23730 NC_018658.1 4902106 4902843 R hypothetical protein complement(4902106..4902843) Escherichia coli O104:H4 str. 2011C-3493 13700003 YP_006781396.1 CDS O3K_23735 NC_018658.1 4902840 4903478 R hypothetical protein complement(4902840..4903478) Escherichia coli O104:H4 str. 2011C-3493 13700004 YP_006781397.1 CDS pgi NC_018658.1 4904189 4905838 R COG0166 Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase complement(4904189..4905838) Escherichia coli O104:H4 str. 2011C-3493 13700005 YP_006781398.1 CDS O3K_23745 NC_018658.1 4906363 4907712 D COG0527 Aspartokinases; aspartate kinase III 4906363..4907712 Escherichia coli O104:H4 str. 2011C-3493 13700006 YP_006781399.1 CDS O3K_23750 NC_018658.1 4907857 4908783 D COG0464 ATPases of the AAA+ class; hypothetical protein 4907857..4908783 Escherichia coli O104:H4 str. 2011C-3493 13700007 YP_006781400.1 CDS O3K_23755 NC_018658.1 4908819 4909583 R COG3541 Predicted nucleotidyltransferase; hypothetical protein complement(4908819..4909583) Escherichia coli O104:H4 str. 2011C-3493 13700008 YP_006781401.1 CDS O3K_23760 NC_018658.1 4909616 4910743 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein complement(4909616..4910743) Escherichia coli O104:H4 str. 2011C-3493 13700009 YP_006781402.1 CDS O3K_23765 NC_018658.1 4911272 4911544 D hypothetical protein 4911272..4911544 Escherichia coli O104:H4 str. 2011C-3493 13700010 YP_006781403.1 CDS O3K_23770 NC_018658.1 4911545 4912417 R COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridine synthase F complement(4911545..4912417) Escherichia coli O104:H4 str. 2011C-3493 13700011 YP_006781404.1 CDS O3K_23775 NC_018658.1 4912629 4913318 D COG3340 Peptidase E; (alpha)-aspartyl dipeptidase 4912629..4913318 Escherichia coli O104:H4 str. 2011C-3493 13700012 YP_006781405.1 CDS O3K_23780 NC_018658.1 4913409 4915040 R COG1283 Na+/phosphate symporter; transporter complement(4913409..4915040) Escherichia coli O104:H4 str. 2011C-3493 13700013 YP_006781406.1 CDS metH NC_018658.1 4915260 4918943 R COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain; B12-dependent methionine synthase complement(4915260..4918943) Escherichia coli O104:H4 str. 2011C-3493 13700014 YP_006781407.1 CDS O3K_23790 NC_018658.1 4919143 4919967 D COG1414 Transcriptional regulator; IclR family transcriptional regulator 4919143..4919967 Escherichia coli O104:H4 str. 2011C-3493 13700015 YP_006781408.1 CDS O3K_23795 NC_018658.1 4920284 4921858 D ShET2 enterotoxin domain-containing protein 4920284..4921858 Escherichia coli O104:H4 str. 2011C-3493 13700016 YP_006781409.1 CDS aceK NC_018658.1 4921827 4923563 R COG4579 Isocitrate dehydrogenase kinase/phosphatase; bifunctional isocitrate dehydrogenase kinase/phosphatase complement(4921827..4923563) Escherichia coli O104:H4 str. 2011C-3493 13700017 YP_006781410.1 CDS O3K_23805 NC_018658.1 4923844 4925148 R COG2224 Isocitrate lyase; isocitrate lyase complement(4923844..4925148) Escherichia coli O104:H4 str. 2011C-3493 13700018 YP_006781411.1 CDS O3K_23810 NC_018658.1 4925178 4926779 R COG2225 Malate synthase; malate synthase complement(4925178..4926779) Escherichia coli O104:H4 str. 2011C-3493 13700019 YP_006781412.1 CDS O3K_23815 NC_018658.1 4927048 4927977 R COG1897 Homoserine trans-succinylase; homoserine O-succinyltransferase complement(4927048..4927977) Escherichia coli O104:H4 str. 2011C-3493 13700020 YP_006781413.1 CDS O3K_23820 NC_018658.1 4928134 4928577 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 4928134..4928577 Escherichia coli O104:H4 str. 2011C-3493 13700021 YP_006781414.1 CDS purH NC_018658.1 4934411 4936000 D COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4934411..4936000 Escherichia coli O104:H4 str. 2011C-3493 13700027 YP_006781415.1 CDS O3K_23830 NC_018658.1 4936012 4937301 D COG0151 Phosphoribosylamine-glycine ligase; phosphoribosylamine--glycine ligase 4936012..4937301 Escherichia coli O104:H4 str. 2011C-3493 13700028 YP_006781416.1 CDS O3K_23835 NC_018658.1 4937298 4938623 R COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; transcriptional regulatory protein ZraR complement(4937298..4938623) Escherichia coli O104:H4 str. 2011C-3493 13700029 YP_006781417.1 CDS O3K_23840 NC_018658.1 4938620 4939996 R COG0642 Signal transduction histidine kinase; sensor protein ZraS complement(4938620..4939996) Escherichia coli O104:H4 str. 2011C-3493 13700030 YP_006781418.1 CDS zraP NC_018658.1 4940234 4940659 D COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; zinc resistance protein 4940234..4940659 Escherichia coli O104:H4 str. 2011C-3493 13700031 YP_006781419.1 CDS O3K_23850 NC_018658.1 4940661 4941356 R hypothetical protein complement(4940661..4941356) Escherichia coli O104:H4 str. 2011C-3493 13700032 YP_006781420.1 CDS O3K_23855 NC_018658.1 4941369 4941641 R COG0776 Bacterial nucleoid DNA-binding protein; transcriptional regulator HU subunit alpha complement(4941369..4941641) Escherichia coli O104:H4 str. 2011C-3493 13700033 YP_006781421.1 CDS O3K_23860 NC_018658.1 4941828 4942418 R COG3068 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4941828..4942418) Escherichia coli O104:H4 str. 2011C-3493 13700034 YP_006781422.1 CDS O3K_23865 NC_018658.1 4942461 4943132 R COG1515 Deoxyinosine 3'endonuclease (endonuclease V); endonuclease V complement(4942461..4943132) Escherichia coli O104:H4 str. 2011C-3493 13700035 YP_006781423.1 CDS hemE NC_018658.1 4943142 4944206 R COG0407 Uroporphyrinogen-III decarboxylase; uroporphyrinogen decarboxylase complement(4943142..4944206) Escherichia coli O104:H4 str. 2011C-3493 13700036 YP_006781424.1 CDS nudC NC_018658.1 4944246 4945019 R COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; NADH pyrophosphatase complement(4944246..4945019) Escherichia coli O104:H4 str. 2011C-3493 13700037 YP_006781425.1 CDS O3K_23880 NC_018658.1 4945114 4945590 D COG3160 Regulator of sigma D; anti-RNA polymerase sigma 70 factor 4945114..4945590 Escherichia coli O104:H4 str. 2011C-3493 13700038 YP_006781426.1 CDS O3K_23885 NC_018658.1 4945823 4947718 D COG0422 Thiamine biosynthesis protein ThiC; thiamine biosynthesis protein ThiC 4945823..4947718 Escherichia coli O104:H4 str. 2011C-3493 13700039 YP_006781427.1 CDS O3K_23890 NC_018658.1 4947718 4948353 D COG0352 Thiamine monophosphate synthase; thiamine-phosphate pyrophosphorylase 4947718..4948353 Escherichia coli O104:H4 str. 2011C-3493 13700040 YP_006781428.1 CDS O3K_23895 NC_018658.1 4948346 4949101 D COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; thiamin biosynthesis protein ThiF 4948346..4949101 Escherichia coli O104:H4 str. 2011C-3493 13700041 YP_006781429.1 CDS O3K_23900 NC_018658.1 4949085 4949285 D COG2104 Sulfur transfer protein involved in thiamine biosynthesis; sulfur carrier protein ThiS 4949085..4949285 Escherichia coli O104:H4 str. 2011C-3493 13700042 YP_006781430.1 CDS thiG NC_018658.1 4949287 4950057 D COG2022 Uncharacterized enzyme of thiazole biosynthesis; thiazole synthase 4949287..4950057 Escherichia coli O104:H4 str. 2011C-3493 13700043 YP_006781431.1 CDS thiH NC_018658.1 4950054 4951187 D COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; thiamine biosynthesis protein ThiH 4950054..4951187 Escherichia coli O104:H4 str. 2011C-3493 13700044 YP_006781432.1 CDS O3K_23915 NC_018658.1 4951597 4952136 R stationary phase growth adaptation protein complement(4951597..4952136) Escherichia coli O104:H4 str. 2011C-3493 13700045 YP_006781433.1 CDS O3K_23920 NC_018658.1 4952349 4956572 R COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' complement(4952349..4956572) Escherichia coli O104:H4 str. 2011C-3493 13700046 YP_006781434.1 CDS rpoB NC_018658.1 4956649 4960677 R COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-directed RNA polymerase subunit beta complement(4956649..4960677) Escherichia coli O104:H4 str. 2011C-3493 13700047 YP_006781435.1 CDS rplL NC_018658.1 4960997 4961362 R COG0222 Ribosomal protein L7/L12; 50S ribosomal protein L7/L12 complement(4960997..4961362) Escherichia coli O104:H4 str. 2011C-3493 13700048 YP_006781436.1 CDS rplJ NC_018658.1 4961429 4961926 R COG0244 Ribosomal protein L10; 50S ribosomal protein L10 complement(4961429..4961926) Escherichia coli O104:H4 str. 2011C-3493 13700049 YP_006781437.1 CDS rplA NC_018658.1 4962339 4963043 R COG0081 Ribosomal protein L1; 50S ribosomal protein L1 complement(4962339..4963043) Escherichia coli O104:H4 str. 2011C-3493 13700050 YP_006781438.1 CDS rplK NC_018658.1 4963047 4963475 R COG0080 Ribosomal protein L11; 50S ribosomal protein L11 complement(4963047..4963475) Escherichia coli O104:H4 str. 2011C-3493 13700051 YP_006781439.1 CDS nusG NC_018658.1 4963634 4964179 R COG0250 Transcription antiterminator; transcription antitermination protein NusG complement(4963634..4964179) Escherichia coli O104:H4 str. 2011C-3493 13700052 YP_006781440.1 CDS secE NC_018658.1 4964181 4964564 R COG0690 Preprotein translocase subunit SecE; preprotein translocase subunit SecE complement(4964181..4964564) Escherichia coli O104:H4 str. 2011C-3493 13700053 YP_006781441.1 CDS O3K_23960 NC_018658.1 4964794 4965978 R COG0050 GTPases - translation elongation factors; elongation factor Tu complement(4964794..4965978) Escherichia coli O104:H4 str. 2011C-3493 13700054 YP_006781442.1 CDS O3K_23970 NC_018658.1 4966896 4967846 D COG1072 Panthothenate kinase; pantothenate kinase 4966896..4967846 Escherichia coli O104:H4 str. 2011C-3493 13700059 YP_006781443.1 CDS O3K_23975 NC_018658.1 4967875 4968840 R COG1654 Biotin operon repressor; bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor complement(4967875..4968840) Escherichia coli O104:H4 str. 2011C-3493 13700060 YP_006781444.1 CDS murB NC_018658.1 4968837 4969865 R COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylenolpyruvoylglucosamine reductase complement(4968837..4969865) Escherichia coli O104:H4 str. 2011C-3493 13700061 YP_006781445.1 CDS O3K_23985 NC_018658.1 4975644 4976501 R COG0796 Glutamate racemase; glutamate racemase complement(4975644..4976501) Escherichia coli O104:H4 str. 2011C-3493 13700067 YP_006781446.1 CDS btuB NC_018658.1 4976446 4978290 R COG4206 Outer membrane cobalamin receptor protein; vitamin B12/cobalamin outer membrane transporter complement(4976446..4978290) Escherichia coli O104:H4 str. 2011C-3493 13700068 YP_006781447.1 CDS O3K_23995 NC_018658.1 4978659 4979759 D COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; tRNA (uracil-5-)-methyltransferase 4978659..4979759 Escherichia coli O104:H4 str. 2011C-3493 13700069 YP_006781448.1 CDS O3K_24000 NC_018658.1 4979799 4980158 R hypothetical protein complement(4979799..4980158) Escherichia coli O104:H4 str. 2011C-3493 13700070 YP_006781449.1 CDS O3K_24005 NC_018658.1 4980158 4980862 R COG1309 Transcriptional regulator; DNA-binding transcriptional repressor FabR complement(4980158..4980862) Escherichia coli O104:H4 str. 2011C-3493 13700071 YP_006781450.1 CDS O3K_24010 NC_018658.1 4981139 4982539 D COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; soluble pyridine nucleotide transhydrogenase 4981139..4982539 Escherichia coli O104:H4 str. 2011C-3493 13700072 YP_006781451.1 CDS O3K_24015 NC_018658.1 4982522 4983439 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator OxyR complement(4982522..4983439) Escherichia coli O104:H4 str. 2011C-3493 13700073 YP_006781452.1 CDS O3K_24020 NC_018658.1 4983690 4984973 R COG0477 Permeases of the major facilitator superfamily; transporter complement(4983690..4984973) Escherichia coli O104:H4 str. 2011C-3493 13700074 YP_006781453.1 CDS O3K_24025 NC_018658.1 4985040 4986254 R COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; bifunctional D-altronate/D-mannonate dehydratase complement(4985040..4986254) Escherichia coli O104:H4 str. 2011C-3493 13700075 YP_006781454.1 CDS O3K_24030 NC_018658.1 4986752 4988125 R COG0165 Argininosuccinate lyase; argininosuccinate lyase complement(4986752..4988125) Escherichia coli O104:H4 str. 2011C-3493 13700076 YP_006781455.1 CDS O3K_24035 NC_018658.1 4988186 4988959 R COG0548 Acetylglutamate kinase; acetylglutamate kinase complement(4988186..4988959) Escherichia coli O104:H4 str. 2011C-3493 13700077 YP_006781456.1 CDS argC NC_018658.1 4988970 4989974 R COG0002 Acetylglutamate semialdehyde dehydrogenase; N-acetyl-gamma-glutamyl-phosphate reductase complement(4988970..4989974) Escherichia coli O104:H4 str. 2011C-3493 13700078 YP_006781457.1 CDS O3K_24045 NC_018658.1 4990128 4991279 D COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase 4990128..4991279 Escherichia coli O104:H4 str. 2011C-3493 13700079 YP_006781458.1 CDS O3K_24050 NC_018658.1 4991631 4994282 D COG2352 Phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase 4991631..4994282 Escherichia coli O104:H4 str. 2011C-3493 13700080 YP_006781459.1 CDS O3K_24055 NC_018658.1 4994465 4996198 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; hypothetical protein 4994465..4996198 Escherichia coli O104:H4 str. 2011C-3493 13700081 YP_006781460.1 CDS O3K_24060 NC_018658.1 4996413 4997264 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 4996413..4997264 Escherichia coli O104:H4 str. 2011C-3493 13700082 YP_006781461.1 CDS O3K_24065 NC_018658.1 4997251 4997592 R COG1445 Phosphotransferase system fructose-specific component IIB; PTS system fructose-like transporter subunit EIIB complement(4997251..4997592) Escherichia coli O104:H4 str. 2011C-3493 13700083 YP_006781462.1 CDS O3K_24070 NC_018658.1 4997594 4998472 R COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase II activase complement(4997594..4998472) Escherichia coli O104:H4 str. 2011C-3493 13700084 YP_006781463.1 CDS pflD NC_018658.1 4998438 5000735 R COG1882 Pyruvate-formate lyase; putative formate acetyltransferase 2 complement(4998438..5000735) Escherichia coli O104:H4 str. 2011C-3493 13700085 YP_006781464.1 CDS O3K_24080 NC_018658.1 5000786 5001106 R COG1445 Phosphotransferase system fructose-specific component IIB; PTS system fructose-like transporter subunit EIIB complement(5000786..5001106) Escherichia coli O104:H4 str. 2011C-3493 13700086 YP_006781465.1 CDS O3K_24085 NC_018658.1 5001121 5002200 R COG1299 Phosphotransferase system, fructose-specific IIC component; PTS system fructose-like transporter subunit IIC complement(5001121..5002200) Escherichia coli O104:H4 str. 2011C-3493 13700087 YP_006781466.1 CDS O3K_24090 NC_018658.1 5002509 5005010 D COG1925 Phosphotransferase system, HPr-related proteins; PTS system transporter proteins Hpr/EI/IIA 5002509..5005010 Escherichia coli O104:H4 str. 2011C-3493 13700088 YP_006781467.1 CDS O3K_24095 NC_018658.1 5005022 5005684 D COG0176 Transaldolase; fructose-6-phosphate aldolase 5005022..5005684 Escherichia coli O104:H4 str. 2011C-3493 13700089 YP_006781468.1 CDS gldA NC_018658.1 5005695 5006798 D COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase 5005695..5006798 Escherichia coli O104:H4 str. 2011C-3493 13700090 YP_006781469.1 CDS O3K_24105 NC_018658.1 5006830 5006961 D hypothetical protein 5006830..5006961 Escherichia coli O104:H4 str. 2011C-3493 13700091 YP_006781470.1 CDS O3K_24110 NC_018658.1 5007073 5007690 D COG3738 Uncharacterized protein conserved in bacteria; hypothetical protein 5007073..5007690 Escherichia coli O104:H4 str. 2011C-3493 13700092 YP_006781471.1 CDS O3K_24115 NC_018658.1 5007717 5008622 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein complement(5007717..5008622) Escherichia coli O104:H4 str. 2011C-3493 13700093 YP_006781472.1 CDS O3K_24120 NC_018658.1 5008716 5010896 R COG0376 Catalase (peroxidase I); catalase/hydroperoxidase HPI(I) complement(5008716..5010896) Escherichia coli O104:H4 str. 2011C-3493 13700094 YP_006781473.1 CDS metF NC_018658.1 5011225 5012115 R COG0685 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase complement(5011225..5012115) Escherichia coli O104:H4 str. 2011C-3493 13700095 YP_006781474.1 CDS O3K_24130 NC_018658.1 5012191 5012325 D hypothetical protein 5012191..5012325 Escherichia coli O104:H4 str. 2011C-3493 13700096 YP_006781475.1 CDS metL NC_018658.1 5012464 5014896 R COG0527 Aspartokinases; bifunctional aspartate kinase II/homoserine dehydrogenase II complement(5012464..5014896) Escherichia coli O104:H4 str. 2011C-3493 13700097 YP_006781476.1 CDS O3K_24140 NC_018658.1 5014899 5016059 R COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine gamma-synthase complement(5014899..5016059) Escherichia coli O104:H4 str. 2011C-3493 13700098 YP_006781477.1 CDS O3K_24145 NC_018658.1 5016336 5016653 D COG3060 Transcriptional regulator of met regulon; transcriptional repressor protein MetJ 5016336..5016653 Escherichia coli O104:H4 str. 2011C-3493 13700099 YP_006781478.1 CDS O3K_24160 NC_018658.1 5017465 5017737 D COG3677 Transposase and inactivated derivatives; hypothetical protein 5017465..5017737 Escherichia coli O104:H4 str. 2011C-3493 13700100 YP_006781479.1 CDS O3K_24165 NC_018658.1 5017764 5017949 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase 5017764..5017949 Escherichia coli O104:H4 str. 2011C-3493 13700101 YP_006781480.1 CDS O3K_24170 NC_018658.1 5017943 5018257 D COG1662 Transposase and inactivated derivatives, IS1 family; iso-IS1 InsB protein, transposase 5017943..5018257 Escherichia coli O104:H4 str. 2011C-3493 13700102 YP_006781481.1 CDS O3K_24175 NC_018658.1 5018313 5018549 R hypothetical protein complement(5018313..5018549) Escherichia coli O104:H4 str. 2011C-3493 13700103 YP_006781482.1 CDS O3K_24180 NC_018658.1 5018551 5022735 R COG3209 Rhs family protein; rhsB element core protein RshB complement(5018551..5022735) Escherichia coli O104:H4 str. 2011C-3493 13700104 YP_006781483.1 CDS rpmE NC_018658.1 5022895 5023107 R COG0254 Ribosomal protein L31; 50S ribosomal protein L31 complement(5022895..5023107) Escherichia coli O104:H4 str. 2011C-3493 13700105 YP_006781484.1 CDS O3K_24190 NC_018658.1 5023310 5025508 D COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; primosome assembly protein PriA 5023310..5025508 Escherichia coli O104:H4 str. 2011C-3493 13700106 YP_006781485.1 CDS O3K_24195 NC_018658.1 5025664 5026689 D COG1609 Transcriptional regulators; DNA-binding transcriptional regulator CytR 5025664..5026689 Escherichia coli O104:H4 str. 2011C-3493 13700107 YP_006781486.1 CDS O3K_24200 NC_018658.1 5026781 5027740 D COG3087 Cell division protein; cell division protein FtsN 5026781..5027740 Escherichia coli O104:H4 str. 2011C-3493 13700108 YP_006781487.1 CDS O3K_24205 NC_018658.1 5027833 5028363 D COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit; ATP-dependent protease subunit HslV 5027833..5028363 Escherichia coli O104:H4 str. 2011C-3493 13700109 YP_006781488.1 CDS hslU NC_018658.1 5028373 5029704 D COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit; ATP-dependent protease ATP-binding subunit HslU 5028373..5029704 Escherichia coli O104:H4 str. 2011C-3493 13700110 YP_006781489.1 CDS O3K_24215 NC_018658.1 5029771 5030697 D COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 5029771..5030697 Escherichia coli O104:H4 str. 2011C-3493 13700111 YP_006781490.1 CDS O3K_24220 NC_018658.1 5030790 5031275 D COG0684 Demethylmenaquinone methyltransferase; ribonuclease activity regulator protein RraA 5030790..5031275 Escherichia coli O104:H4 str. 2011C-3493 13700112 YP_006781491.1 CDS O3K_24225 NC_018658.1 5031360 5031599 R COG3074 Uncharacterized protein conserved in bacteria; septal ring assembly protein ZapB complement(5031360..5031599) Escherichia coli O104:H4 str. 2011C-3493 13700113 YP_006781492.1 CDS O3K_24230 NC_018658.1 5032031 5032876 D COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator protein 5032031..5032876 Escherichia coli O104:H4 str. 2011C-3493 13700114 YP_006781493.1 CDS glpK NC_018658.1 5032899 5034407 D COG0554 Glycerol kinase; glycerol kinase 5032899..5034407 Escherichia coli O104:H4 str. 2011C-3493 13700115 YP_006781494.1 CDS glpX NC_018658.1 5034543 5035553 D COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; fructose 1,6-bisphosphatase II 5034543..5035553 Escherichia coli O104:H4 str. 2011C-3493 13700116 YP_006781495.1 CDS O3K_24245 NC_018658.1 5035650 5036396 D COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; ferredoxin-NADP reductase 5035650..5036396 Escherichia coli O104:H4 str. 2011C-3493 13700117 YP_006781496.1 CDS O3K_24250 NC_018658.1 5036401 5036829 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspD complement(5036401..5036829) Escherichia coli O104:H4 str. 2011C-3493 13700118 YP_006781497.1 CDS O3K_24255 NC_018658.1 5036856 5037155 R COG3691 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5036856..5037155) Escherichia coli O104:H4 str. 2011C-3493 13700119 YP_006781498.1 CDS O3K_24260 NC_018658.1 5037367 5037807 R COG3152 Predicted membrane protein; inner membrane protein complement(5037367..5037807) Escherichia coli O104:H4 str. 2011C-3493 13700120 YP_006781499.1 CDS O3K_24265 NC_018658.1 5037908 5038507 D hypothetical protein 5037908..5038507 Escherichia coli O104:H4 str. 2011C-3493 13700121 YP_006781500.1 CDS tpiA NC_018658.1 5038615 5039382 D COG0149 Triosephosphate isomerase; triosephosphate isomerase 5038615..5039382 Escherichia coli O104:H4 str. 2011C-3493 13700122 YP_006781501.1 CDS O3K_24275 NC_018658.1 5039437 5040192 R COG2134 CDP-diacylglycerol pyrophosphatase; CDP-diacylglycerol pyrophosphatase complement(5039437..5040192) Escherichia coli O104:H4 str. 2011C-3493 13700123 YP_006781502.1 CDS O3K_24280 NC_018658.1 5040299 5041288 R COG1613 ABC-type sulfate transport system, periplasmic component; sulfate transporter subunit complement(5040299..5041288) Escherichia coli O104:H4 str. 2011C-3493 13700124 YP_006781503.1 CDS O3K_24285 NC_018658.1 5041608 5042570 R COG0205 6-phosphofructokinase; 6-phosphofructokinase complement(5041608..5042570) Escherichia coli O104:H4 str. 2011C-3493 13700125 YP_006781504.1 CDS fieF NC_018658.1 5042751 5043653 R COG0053 Predicted Co/Zn/Cd cation transporters; ferrous iron efflux protein F complement(5042751..5043653) Escherichia coli O104:H4 str. 2011C-3493 13700126 YP_006781505.1 CDS cpxP NC_018658.1 5043802 5044302 R COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; repressor CpxP complement(5043802..5044302) Escherichia coli O104:H4 str. 2011C-3493 13700127 YP_006781506.1 CDS O3K_24300 NC_018658.1 5044452 5045150 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator CpxR 5044452..5045150 Escherichia coli O104:H4 str. 2011C-3493 13700128 YP_006781507.1 CDS cpxA NC_018658.1 5045147 5046520 D COG0642 Signal transduction histidine kinase; two-component sensor protein 5045147..5046520 Escherichia coli O104:H4 str. 2011C-3493 13700129 YP_006781508.1 CDS O3K_24310 NC_018658.1 5046626 5047300 R COG2258 Uncharacterized protein conserved in bacteria; 6-N-hydroxylaminopurine resistance protein complement(5046626..5047300) Escherichia coli O104:H4 str. 2011C-3493 13700130 YP_006781509.1 CDS O3K_24315 NC_018658.1 5047449 5048432 R 2-keto-3-deoxygluconate permease complement(5047449..5048432) Escherichia coli O104:H4 str. 2011C-3493 13700131 YP_006781510.1 CDS O3K_24320 NC_018658.1 5048692 5049312 R COG0605 Superoxide dismutase; superoxide dismutase complement(5048692..5049312) Escherichia coli O104:H4 str. 2011C-3493 13700132 YP_006781511.1 CDS O3K_24325 NC_018658.1 5049597 5050631 D rhamnose-proton symporter 5049597..5050631 Escherichia coli O104:H4 str. 2011C-3493 13700133 YP_006781512.1 CDS O3K_24330 NC_018658.1 5050628 5051566 R COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator RhaR complement(5050628..5051566) Escherichia coli O104:H4 str. 2011C-3493 13700134 YP_006781513.1 CDS O3K_24335 NC_018658.1 5051550 5052386 R COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator RhaS complement(5051550..5052386) Escherichia coli O104:H4 str. 2011C-3493 13700135 YP_006781514.1 CDS O3K_24340 NC_018658.1 5052446 5052595 R hypothetical protein complement(5052446..5052595) Escherichia coli O104:H4 str. 2011C-3493 13700136 YP_006781515.1 CDS rhaB NC_018658.1 5052674 5054143 D COG1070 Sugar (pentulose and hexulose) kinases; rhamnulokinase 5052674..5054143 Escherichia coli O104:H4 str. 2011C-3493 13700137 YP_006781516.1 CDS O3K_24350 NC_018658.1 5054140 5055399 D COG4806 L-rhamnose isomerase; L-rhamnose isomerase 5054140..5055399 Escherichia coli O104:H4 str. 2011C-3493 13700138 YP_006781517.1 CDS O3K_24355 NC_018658.1 5055641 5056465 D COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; rhamnulose-1-phosphate aldolase 5055641..5056465 Escherichia coli O104:H4 str. 2011C-3493 13700139 YP_006781518.1 CDS O3K_24360 NC_018658.1 5056475 5056789 D COG3254 Uncharacterized conserved protein; L-rhamnose mutarotase 5056475..5056789 Escherichia coli O104:H4 str. 2011C-3493 13700140 YP_006781519.1 CDS O3K_24365 NC_018658.1 5057102 5057548 D COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); putative fructose-like phosphotransferase system subunit EIIA 5057102..5057548 Escherichia coli O104:H4 str. 2011C-3493 13700141 YP_006781520.1 CDS O3K_24370 NC_018658.1 5057559 5059010 D COG1445 Phosphotransferase system fructose-specific component IIB; PTS system transporter subunits IIBC 5057559..5059010 Escherichia coli O104:H4 str. 2011C-3493 13700142 YP_006781521.1 CDS O3K_24375 NC_018658.1 5059000 5060070 D COG1363 Cellulase M and related proteins; peptidase 5059000..5060070 Escherichia coli O104:H4 str. 2011C-3493 13700143 YP_006781522.1 CDS O3K_24380 NC_018658.1 5060070 5061818 D COG3711 Transcriptional antiterminator; putative frv operon regulatory protein 5060070..5061818 Escherichia coli O104:H4 str. 2011C-3493 13700144 YP_006781523.1 CDS O3K_24385 NC_018658.1 5061868 5062908 R hypothetical protein complement(5061868..5062908) Escherichia coli O104:H4 str. 2011C-3493 13700145 YP_006781524.1 CDS O3K_24390 NC_018658.1 5063061 5063894 R COG1526 Uncharacterized protein required for formate dehydrogenase activity; formate dehydrogenase accessory protein complement(5063061..5063894) Escherichia coli O104:H4 str. 2011C-3493 13700146 YP_006781525.1 CDS O3K_24395 NC_018658.1 5064088 5064675 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-O, large subunit 5064088..5064675 Escherichia coli O104:H4 str. 2011C-3493 13700147 YP_006781526.1 CDS O3K_24400 NC_018658.1 5064724 5067138 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-O, major subunit 5064724..5067138 Escherichia coli O104:H4 str. 2011C-3493 13700148 YP_006781527.1 CDS O3K_24405 NC_018658.1 5067151 5068053 D COG0437 Fe-S-cluster-containing hydrogenase components 1; formate dehydrogenase-O, iron-sulfur subunit 5067151..5068053 Escherichia coli O104:H4 str. 2011C-3493 13700149 YP_006781528.1 CDS O3K_24410 NC_018658.1 5068050 5068685 D COG2864 Cytochrome b subunit of formate dehydrogenase; formate dehydrogenase-O subunit gamma 5068050..5068685 Escherichia coli O104:H4 str. 2011C-3493 13700150 YP_006781529.1 CDS O3K_24415 NC_018658.1 5068682 5069611 D COG3058 Uncharacterized protein involved in formate dehydrogenase formation; formate dehydrogenase accessory protein FdhE 5068682..5069611 Escherichia coli O104:H4 str. 2011C-3493 13700151 YP_006781530.1 CDS O3K_24420 NC_018658.1 5069791 5069925 D hypothetical protein 5069791..5069925 Escherichia coli O104:H4 str. 2011C-3493 13700152 YP_006781531.1 CDS O3K_24425 NC_018658.1 5069941 5070183 R COG1219 ATP-dependent protease Clp, ATPase subunit; hypothetical protein complement(5069941..5070183) Escherichia coli O104:H4 str. 2011C-3493 13700153 YP_006781532.1 CDS O3K_24430 NC_018658.1 5070403 5070621 R COG3905 Predicted transcriptional regulator; transcriptional regulator complement(5070403..5070621) Escherichia coli O104:H4 str. 2011C-3493 13700154 YP_006781533.1 CDS O3K_24435 NC_018658.1 5071207 5071497 R COG2944 Predicted transcriptional regulator; hypothetical protein complement(5071207..5071497) Escherichia coli O104:H4 str. 2011C-3493 13700155 YP_006781534.1 CDS O3K_24440 NC_018658.1 5071498 5071809 R hypothetical protein complement(5071498..5071809) Escherichia coli O104:H4 str. 2011C-3493 13700156 YP_006781535.1 CDS O3K_24445 NC_018658.1 5072038 5072946 D COG0657 Esterase/lipase; putative lipase 5072038..5072946 Escherichia coli O104:H4 str. 2011C-3493 13700157 YP_006781536.1 CDS O3K_24450 NC_018658.1 5073010 5073999 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase complement(5073010..5073999) Escherichia coli O104:H4 str. 2011C-3493 13700158 YP_006781537.1 CDS O3K_24455 NC_018658.1 5073996 5074433 R COG1490 D-Tyr-tRNAtyr deacylase; D-tyrosyl-tRNA(Tyr) deacylase complement(5073996..5074433) Escherichia coli O104:H4 str. 2011C-3493 13700159 YP_006781538.1 CDS O3K_24460 NC_018658.1 5074430 5075302 R COG1295 Predicted membrane protein; hypothetical protein complement(5074430..5075302) Escherichia coli O104:H4 str. 2011C-3493 13700160 YP_006781539.1 CDS O3K_24465 NC_018658.1 5075296 5075895 R COG1011 Predicted hydrolase (HAD superfamily); alpha-D-glucose-1-phosphatase complement(5075296..5075895) Escherichia coli O104:H4 str. 2011C-3493 13700161 YP_006781540.1 CDS O3K_24470 NC_018658.1 5076036 5076923 R COG2017 Galactose mutarotase and related enzymes; galactose mutarotase complement(5076036..5076923) Escherichia coli O104:H4 str. 2011C-3493 13700162 YP_006781541.1 CDS O3K_24475 NC_018658.1 5076913 5078262 R COG0477 Permeases of the major facilitator superfamily; transporter complement(5076913..5078262) Escherichia coli O104:H4 str. 2011C-3493 13700163 YP_006781542.1 CDS O3K_24480 NC_018658.1 5078361 5079794 R COG0477 Permeases of the major facilitator superfamily; transporter complement(5078361..5079794) Escherichia coli O104:H4 str. 2011C-3493 13700164 YP_006781543.1 CDS O3K_24485 NC_018658.1 5079864 5080874 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; dehydrogenase, GroES-like protein complement(5079864..5080874) Escherichia coli O104:H4 str. 2011C-3493 13700165 YP_006781544.1 CDS O3K_24490 NC_018658.1 5080907 5081794 R COG3684 Tagatose-1,6-bisphosphate aldolase; aldolase yihT complement(5080907..5081794) Escherichia coli O104:H4 str. 2011C-3493 13700166 YP_006781545.1 CDS O3K_24495 NC_018658.1 5081819 5082697 R COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; NADH-dependent gamma-hydroxybutyrate dehydrogenase complement(5081819..5082697) Escherichia coli O104:H4 str. 2011C-3493 13700167 YP_006781546.1 CDS O3K_24500 NC_018658.1 5082870 5083766 D COG0524 Sugar kinases, ribokinase family; sugar kinase 5082870..5083766 Escherichia coli O104:H4 str. 2011C-3493 13700168 YP_006781547.1 CDS O3K_24505 NC_018658.1 5083806 5084594 D COG1349 Transcriptional regulators of sugar metabolism; DEOR-type transcriptional regulator 5083806..5084594 Escherichia coli O104:H4 str. 2011C-3493 13700169 YP_006781548.1 CDS O3K_24510 NC_018658.1 5084705 5085970 R COG0477 Permeases of the major facilitator superfamily; transporter complement(5084705..5085970) Escherichia coli O104:H4 str. 2011C-3493 13700170 YP_006781549.1 CDS O3K_24515 NC_018658.1 5086072 5087052 R COG1082 Sugar phosphate isomerases/epimerases; sugar phosphate isomerase complement(5086072..5087052) Escherichia coli O104:H4 str. 2011C-3493 13700171 YP_006781550.1 CDS O3K_24520 NC_018658.1 5087060 5087770 R COG2188 Transcriptional regulators; putative DNA-binding transcriptional regulator complement(5087060..5087770) Escherichia coli O104:H4 str. 2011C-3493 13700172 YP_006781551.1 CDS O3K_24525 NC_018658.1 5087987 5089810 R COG1217 Predicted membrane GTPase involved in stress response; GTP-binding protein complement(5087987..5089810) Escherichia coli O104:H4 str. 2011C-3493 13700173 YP_006781552.1 CDS glnA NC_018658.1 5090183 5091592 D COG0174 Glutamine synthetase; glutamine synthetase 5090183..5091592 Escherichia coli O104:H4 str. 2011C-3493 13700174 YP_006781553.1 CDS glnL NC_018658.1 5091878 5092927 D COG3852 Signal transduction histidine kinase, nitrogen specific; nitrogen regulation protein NR(II) 5091878..5092927 Escherichia coli O104:H4 str. 2011C-3493 13700175 YP_006781554.1 CDS glnG NC_018658.1 5092939 5094348 D COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; nitrogen regulation protein NR(I) 5092939..5094348 Escherichia coli O104:H4 str. 2011C-3493 13700176 YP_006781555.1 CDS O3K_24545 NC_018658.1 5094460 5094570 D hypothetical protein 5094460..5094570 Escherichia coli O104:H4 str. 2011C-3493 13700177 YP_006781556.1 CDS O3K_24550 NC_018658.1 5094760 5096133 R COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; coproporphyrinogen III oxidase complement(5094760..5096133) Escherichia coli O104:H4 str. 2011C-3493 13700178 YP_006781557.1 CDS O3K_24555 NC_018658.1 5096322 5096831 R COG3078 Uncharacterized protein conserved in bacteria; GTPase activator complement(5096322..5096831) Escherichia coli O104:H4 str. 2011C-3493 13700179 YP_006781558.1 CDS O3K_24560 NC_018658.1 5097039 5097116 R hypothetical protein complement(5097039..5097116) Escherichia coli O104:H4 str. 2011C-3493 13700180 YP_006781559.1 CDS engB NC_018658.1 5097413 5098045 D COG0218 Predicted GTPase; GTP-binding protein YsxC 5097413..5098045 Escherichia coli O104:H4 str. 2011C-3493 13700181 YP_006781560.1 CDS O3K_24570 NC_018658.1 5098427 5101213 R COG0258 5'-3' exonuclease (including N-terminal domain of PolI); DNA polymerase I complement(5098427..5101213) Escherichia coli O104:H4 str. 2011C-3493 13700182 YP_006781561.1 CDS O3K_24575 NC_018658.1 5101215 5101457 D hypothetical protein 5101215..5101457 Escherichia coli O104:H4 str. 2011C-3493 13700183 YP_006781562.1 CDS O3K_24580 NC_018658.1 5101577 5102509 D COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative acyltransferase 5101577..5102509 Escherichia coli O104:H4 str. 2011C-3493 13700184 YP_006781563.1 CDS O3K_24585 NC_018658.1 5102550 5103980 R COG5339 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5102550..5103980) Escherichia coli O104:H4 str. 2011C-3493 13700185 YP_006781564.1 CDS O3K_24590 NC_018658.1 5104135 5104761 R COG0526 Thiol-disulfide isomerase and thioredoxins; protein disulfide isomerase I complement(5104135..5104761) Escherichia coli O104:H4 str. 2011C-3493 13700186 YP_006781565.1 CDS O3K_24595 NC_018658.1 5104778 5105764 R COG2334 Putative homoserine kinase type II (protein kinase fold); serine/threonine protein kinase complement(5104778..5105764) Escherichia coli O104:H4 str. 2011C-3493 13700187 YP_006781566.1 CDS O3K_24600 NC_018658.1 5105841 5106110 R COG3084 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5105841..5106110) Escherichia coli O104:H4 str. 2011C-3493 13700188 YP_006781567.1 CDS mobA NC_018658.1 5106180 5106764 D COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; molybdopterin-guanine dinucleotide biosynthesis protein MobA 5106180..5106764 Escherichia coli O104:H4 str. 2011C-3493 13700189 YP_006781568.1 CDS O3K_24610 NC_018658.1 5106746 5107273 D COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; molybdopterin-guanine dinucleotide biosynthesis protein MobB 5106746..5107273 Escherichia coli O104:H4 str. 2011C-3493 13700190 YP_006781569.1 CDS hemG NC_018658.1 5112859 5113404 R COG4635 Flavodoxin; protoporphyrinogen oxidase complement(5112859..5113404) Escherichia coli O104:H4 str. 2011C-3493 13700196 YP_006781570.1 CDS O3K_24620 NC_018658.1 5113416 5114867 R COG0168 Trk-type K+ transport systems, membrane components; potassium transporter complement(5113416..5114867) Escherichia coli O104:H4 str. 2011C-3493 13700197 YP_006781571.1 CDS O3K_24625 NC_018658.1 5114906 5115520 R COG1739 Uncharacterized conserved protein; hypothetical protein complement(5114906..5115520) Escherichia coli O104:H4 str. 2011C-3493 13700198 YP_006781572.1 CDS O3K_24630 NC_018658.1 5115520 5116851 R COG0006 Xaa-Pro aminopeptidase; proline dipeptidase complement(5115520..5116851) Escherichia coli O104:H4 str. 2011C-3493 13700199 YP_006781573.1 CDS fadB NC_018658.1 5117041 5119230 D COG1024 Enoyl-CoA hydratase/carnithine racemase; multifunctional fatty acid oxidation complex subunit alpha 5117041..5119230 Escherichia coli O104:H4 str. 2011C-3493 13700200 YP_006781574.1 CDS fadA NC_018658.1 5119240 5120403 D COG0183 Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase 5119240..5120403 Escherichia coli O104:H4 str. 2011C-3493 13700201 YP_006781575.1 CDS fre NC_018658.1 5120595 5121296 R COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; FMN reductase complement(5120595..5121296) Escherichia coli O104:H4 str. 2011C-3493 13700202 YP_006781576.1 CDS O3K_24650 NC_018658.1 5121342 5122835 R COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(5121342..5122835) Escherichia coli O104:H4 str. 2011C-3493 13700203 YP_006781577.1 CDS rfaH NC_018658.1 5123002 5123490 D COG0250 Transcription antiterminator; transcriptional activator RfaH 5123002..5123490 Escherichia coli O104:H4 str. 2011C-3493 13700204 YP_006781578.1 CDS O3K_24660 NC_018658.1 5123487 5124269 R COG0084 Mg-dependent DNase; DNase TatD complement(5123487..5124269) Escherichia coli O104:H4 str. 2011C-3493 13700205 YP_006781579.1 CDS O3K_24665 NC_018658.1 5124311 5125087 R COG0805 Sec-independent protein secretion pathway component TatC; twin-arginine protein translocation system subunit TatC complement(5124311..5125087) Escherichia coli O104:H4 str. 2011C-3493 13700206 YP_006781580.1 CDS O3K_24670 NC_018658.1 5125090 5125605 R COG1826 Sec-independent protein secretion pathway components; sec-independent translocase complement(5125090..5125605) Escherichia coli O104:H4 str. 2011C-3493 13700207 YP_006781581.1 CDS tatA NC_018658.1 5125609 5125878 R COG1826 Sec-independent protein secretion pathway components; twin arginine translocase protein A complement(5125609..5125878) Escherichia coli O104:H4 str. 2011C-3493 13700208 YP_006781582.1 CDS ubiB NC_018658.1 5125957 5127597 R COG0661 Predicted unusual protein kinase; putative ubiquinone biosynthesis protein UbiB complement(5125957..5127597) Escherichia coli O104:H4 str. 2011C-3493 13700209 YP_006781583.1 CDS O3K_24685 NC_018658.1 5127594 5128199 R COG3165 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5127594..5128199) Escherichia coli O104:H4 str. 2011C-3493 13700210 YP_006781584.1 CDS ubiE NC_018658.1 5128213 5128968 R COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; ubiquinone/menaquinone biosynthesis methyltransferase complement(5128213..5128968) Escherichia coli O104:H4 str. 2011C-3493 13700211 YP_006781585.1 CDS O3K_24695 NC_018658.1 5129063 5130490 R COG1322 Uncharacterized protein conserved in bacteria; DNA recombination protein RmuC complement(5129063..5130490) Escherichia coli O104:H4 str. 2011C-3493 13700212 YP_006781586.1 CDS O3K_24700 NC_018658.1 5130631 5131392 R COG2820 Uridine phosphorylase; uridine phosphorylase complement(5130631..5131392) Escherichia coli O104:H4 str. 2011C-3493 13700213 YP_006781587.1 CDS O3K_24705 NC_018658.1 5131654 5132469 D COG0412 Dienelactone hydrolase and related enzymes; hydrolase 5131654..5132469 Escherichia coli O104:H4 str. 2011C-3493 13700214 YP_006781588.1 CDS O3K_24710 NC_018658.1 5132508 5134769 R COG0620 Methionine synthase II (cobalamin-independent); 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase complement(5132508..5134769) Escherichia coli O104:H4 str. 2011C-3493 13700215 YP_006781589.1 CDS O3K_24715 NC_018658.1 5134887 5135840 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator MetR 5134887..5135840 Escherichia coli O104:H4 str. 2011C-3493 13700216 YP_006781590.1 CDS O3K_24720 NC_018658.1 5135728 5136627 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein complement(5135728..5136627) Escherichia coli O104:H4 str. 2011C-3493 13700217 YP_006781591.1 CDS O3K_24725 NC_018658.1 5136703 5137503 R COG0561 Predicted hydrolases of the HAD superfamily; hydrolase complement(5136703..5137503) Escherichia coli O104:H4 str. 2011C-3493 13700218 YP_006781592.1 CDS O3K_24730 NC_018658.1 5137511 5138533 R COG2267 Lysophospholipase; lysophospholipase L2 complement(5137511..5138533) Escherichia coli O104:H4 str. 2011C-3493 13700219 YP_006781593.1 CDS rhtB NC_018658.1 5138644 5139264 D COG1280 Putative threonine efflux protein; homoserine/homoserine lactone efflux protein 5138644..5139264 Escherichia coli O104:H4 str. 2011C-3493 13700220 YP_006781594.1 CDS O3K_24740 NC_018658.1 5139326 5139946 R COG1280 Putative threonine efflux protein; threonine efflux system complement(5139326..5139946) Escherichia coli O104:H4 str. 2011C-3493 13700221 YP_006781595.1 CDS O3K_24745 NC_018658.1 5140010 5141839 R COG0514 Superfamily II DNA helicase; ATP-dependent DNA helicase RecQ complement(5140010..5141839) Escherichia coli O104:H4 str. 2011C-3493 13700222 YP_006781596.1 CDS O3K_24750 NC_018658.1 5141972 5142841 R COG2829 Outer membrane phospholipase A; phospholipase A complement(5141972..5142841) Escherichia coli O104:H4 str. 2011C-3493 13700223 YP_006781597.1 CDS O3K_24755 NC_018658.1 5143006 5143473 D COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein 5143006..5143473 Escherichia coli O104:H4 str. 2011C-3493 13700224 YP_006781598.1 CDS O3K_24760 NC_018658.1 5143525 5144412 D COG2962 Predicted permeases; putative chloramphenical resistance permease RarD 5143525..5144412 Escherichia coli O104:H4 str. 2011C-3493 13700225 YP_006781599.1 CDS O3K_24765 NC_018658.1 5144459 5144758 R hypothetical protein complement(5144459..5144758) Escherichia coli O104:H4 str. 2011C-3493 13700226 YP_006781600.1 CDS O3K_24770 NC_018658.1 5145404 5145601 R COG0598 Mg2+ and Co2+ transporters; hypothetical protein complement(5145404..5145601) Escherichia coli O104:H4 str. 2011C-3493 13700227 YP_006781601.1 CDS O3K_24775 NC_018658.1 5145737 5146585 D hypothetical protein 5145737..5146585 Escherichia coli O104:H4 str. 2011C-3493 13700228 YP_006781602.1 CDS O3K_24780 NC_018658.1 5146582 5147073 D hypothetical protein 5146582..5147073 Escherichia coli O104:H4 str. 2011C-3493 13700229 YP_006781603.1 CDS O3K_24785 NC_018658.1 5147115 5148065 R COG0598 Mg2+ and Co2+ transporters; magnesium/nickel/cobalt transporter CorA complement(5147115..5148065) Escherichia coli O104:H4 str. 2011C-3493 13700230 YP_006781604.1 CDS O3K_24790 NC_018658.1 5148309 5148443 R hypothetical protein complement(5148309..5148443) Escherichia coli O104:H4 str. 2011C-3493 13700231 YP_006781605.1 CDS O3K_24795 NC_018658.1 5148435 5149199 D COG3698 Predicted periplasmic protein; hypothetical protein 5148435..5149199 Escherichia coli O104:H4 str. 2011C-3493 13700232 YP_006781606.1 CDS uvrD NC_018658.1 5149346 5151508 R COG0210 Superfamily I DNA and RNA helicases; DNA-dependent helicase II complement(5149346..5151508) Escherichia coli O104:H4 str. 2011C-3493 13700233 YP_006781607.1 CDS O3K_24805 NC_018658.1 5151592 5152308 R COG1011 Predicted hydrolase (HAD superfamily); flavin mononucleotide phosphatase complement(5151592..5152308) Escherichia coli O104:H4 str. 2011C-3493 13700234 YP_006781608.1 CDS xerC NC_018658.1 5152308 5153204 R COG4973 Site-specific recombinase XerC; site-specific tyrosine recombinase XerC complement(5152308..5153204) Escherichia coli O104:H4 str. 2011C-3493 13700235 YP_006781609.1 CDS O3K_24815 NC_018658.1 5153201 5153908 R COG3159 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5153201..5153908) Escherichia coli O104:H4 str. 2011C-3493 13700236 YP_006781610.1 CDS dapF NC_018658.1 5153905 5154729 R COG0253 Diaminopimelate epimerase; diaminopimelate epimerase complement(5153905..5154729) Escherichia coli O104:H4 str. 2011C-3493 13700237 YP_006781611.1 CDS O3K_24825 NC_018658.1 5154766 5154969 R COG5567 Predicted small periplasmic lipoprotein; lipoprotein complement(5154766..5154969) Escherichia coli O104:H4 str. 2011C-3493 13700238 YP_006781612.1 CDS O3K_24830 NC_018658.1 5155319 5155873 D hypothetical protein 5155319..5155873 Escherichia coli O104:H4 str. 2011C-3493 13700239 YP_006781613.1 CDS O3K_24835 NC_018658.1 5156241 5157719 D hypothetical protein 5156241..5157719 Escherichia coli O104:H4 str. 2011C-3493 13700240 YP_006781614.1 CDS O3K_24840 NC_018658.1 5157716 5159041 D hypothetical protein 5157716..5159041 Escherichia coli O104:H4 str. 2011C-3493 13700241 YP_006781615.1 CDS cyaY NC_018658.1 5159089 5159409 D COG1965 Protein implicated in iron transport, frataxin homolog; frataxin-like protein 5159089..5159409 Escherichia coli O104:H4 str. 2011C-3493 13700242 YP_006781616.1 CDS cyaA NC_018658.1 5159449 5161995 R COG3072 Adenylate cyclase; adenylate cyclase complement(5159449..5161995) Escherichia coli O104:H4 str. 2011C-3493 13700243 YP_006781617.1 CDS hemC NC_018658.1 5162382 5163323 D COG0181 Porphobilinogen deaminase; porphobilinogen deaminase 5162382..5163323 Escherichia coli O104:H4 str. 2011C-3493 13700244 YP_006781618.1 CDS hemD NC_018658.1 5163320 5164060 D COG1587 Uroporphyrinogen-III synthase; uroporphyrinogen-III synthase 5163320..5164060 Escherichia coli O104:H4 str. 2011C-3493 13700245 YP_006781619.1 CDS O3K_24865 NC_018658.1 5164082 5165317 D COG2959 Uncharacterized enzyme of heme biosynthesis; putative uroporphyrinogen III C-methyltransferase 5164082..5165317 Escherichia coli O104:H4 str. 2011C-3493 13700246 YP_006781620.1 CDS O3K_24870 NC_018658.1 5165320 5166516 D COG3071 Uncharacterized enzyme of heme biosynthesis; putative protoheme IX biogenesis protein 5165320..5166516 Escherichia coli O104:H4 str. 2011C-3493 13700247 YP_006781621.1 CDS O3K_24875 NC_018658.1 5167195 5167356 D hypothetical protein 5167195..5167356 Escherichia coli O104:H4 str. 2011C-3493 13700248 YP_006781622.1 CDS O3K_24880 NC_018658.1 5167440 5168675 R COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); regulator of arylsulfatase activity complement(5167440..5168675) Escherichia coli O104:H4 str. 2011C-3493 13700249 YP_006781623.1 CDS O3K_24885 NC_018658.1 5169361 5170746 R COG1113 Gamma-aminobutyrate permease and related permeases; putative transport protein YifK complement(5169361..5170746) Escherichia coli O104:H4 str. 2011C-3493 13700254 YP_006781624.1 CDS O3K_24890 NC_018658.1 5170937 5171677 R COG1922 Teichoic acid biosynthesis proteins; putative UDP-N-acetyl-D-mannosaminuronic acid transferase complement(5170937..5171677) Escherichia coli O104:H4 str. 2011C-3493 13700255 YP_006781625.1 CDS O3K_24895 NC_018658.1 5171680 5173032 R putative common antigen polymerase complement(5171680..5173032) Escherichia coli O104:H4 str. 2011C-3493 13700256 YP_006781626.1 CDS O3K_24900 NC_018658.1 5173029 5174108 R 4-alpha-L-fucosyltransferase complement(5173029..5174108) Escherichia coli O104:H4 str. 2011C-3493 13700257 YP_006781627.1 CDS O3K_24905 NC_018658.1 5174105 5175355 R COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; O-antigen translocase complement(5174105..5175355) Escherichia coli O104:H4 str. 2011C-3493 13700258 YP_006781628.1 CDS O3K_24910 NC_018658.1 5175357 5176487 R COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; TDP-4-oxo-6-deoxy-D-glucose transaminase complement(5175357..5176487) Escherichia coli O104:H4 str. 2011C-3493 13700259 YP_006781629.1 CDS O3K_24915 NC_018658.1 5176492 5177166 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; TDP-fucosamine acetyltransferase complement(5176492..5177166) Escherichia coli O104:H4 str. 2011C-3493 13700260 YP_006781630.1 CDS O3K_24920 NC_018658.1 5177144 5178025 R COG1209 dTDP-glucose pyrophosphorylase; glucose-1-phosphate thymidylyltransferase complement(5177144..5178025) Escherichia coli O104:H4 str. 2011C-3493 13700261 YP_006781631.1 CDS O3K_24925 NC_018658.1 5178044 5179111 R COG1088 dTDP-D-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase complement(5178044..5179111) Escherichia coli O104:H4 str. 2011C-3493 13700262 YP_006781632.1 CDS wecC NC_018658.1 5179111 5180373 R COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; UDP-N-acetyl-D-mannosamine dehydrogenase complement(5179111..5180373) Escherichia coli O104:H4 str. 2011C-3493 13700263 YP_006781633.1 CDS O3K_24935 NC_018658.1 5180370 5181500 R COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase complement(5180370..5181500) Escherichia coli O104:H4 str. 2011C-3493 13700264 YP_006781634.1 CDS O3K_24940 NC_018658.1 5181556 5182602 R COG3765 Chain length determinant protein; lipopolysaccharide biosynthesis protein WzzE complement(5181556..5182602) Escherichia coli O104:H4 str. 2011C-3493 13700265 YP_006781635.1 CDS O3K_24945 NC_018658.1 5182614 5183717 R COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase complement(5182614..5183717) Escherichia coli O104:H4 str. 2011C-3493 13700266 YP_006781636.1 CDS O3K_24950 NC_018658.1 5183729 5183947 R hypothetical protein complement(5183729..5183947) Escherichia coli O104:H4 str. 2011C-3493 13700267 YP_006781637.1 CDS rho NC_018658.1 5183957 5185216 R COG1158 Transcription termination factor; transcription termination factor Rho complement(5183957..5185216) Escherichia coli O104:H4 str. 2011C-3493 13700268 YP_006781638.1 CDS O3K_24960 NC_018658.1 5185301 5185402 R putative rho operon leader peptide complement(5185301..5185402) Escherichia coli O104:H4 str. 2011C-3493 13700269 YP_006781639.1 CDS trxA NC_018658.1 5185543 5185872 R COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin complement(5185543..5185872) Escherichia coli O104:H4 str. 2011C-3493 13700270 YP_006781640.1 CDS O3K_24970 NC_018658.1 5186003 5187268 D COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlB 5186003..5187268 Escherichia coli O104:H4 str. 2011C-3493 13700271 YP_006781641.1 CDS O3K_24975 NC_018658.1 5187402 5188886 D COG0248 Exopolyphosphatase; guanosine pentaphosphate phosphohydrolase 5187402..5188886 Escherichia coli O104:H4 str. 2011C-3493 13700272 YP_006781642.1 CDS O3K_24980 NC_018658.1 5188933 5190954 R COG0210 Superfamily I DNA and RNA helicases; ATP-dependent DNA helicase Rep complement(5188933..5190954) Escherichia coli O104:H4 str. 2011C-3493 13700273 YP_006781643.1 CDS O3K_24985 NC_018658.1 5191171 5191620 D COG3692 Uncharacterized protein conserved in bacteria; hypothetical protein 5191171..5191620 Escherichia coli O104:H4 str. 2011C-3493 13700274 YP_006781644.1 CDS O3K_24990 NC_018658.1 5191819 5192100 D COG0760 Parvulin-like peptidyl-prolyl isomerase; peptidyl-prolyl cis-trans isomerase C 5191819..5192100 Escherichia coli O104:H4 str. 2011C-3493 13700275 YP_006781645.1 CDS O3K_24995 NC_018658.1 5192187 5193662 R COG0059 Ketol-acid reductoisomerase; ketol-acid reductoisomerase complement(5192187..5193662) Escherichia coli O104:H4 str. 2011C-3493 13700276 YP_006781646.1 CDS O3K_25000 NC_018658.1 5193812 5194705 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator IlvY 5193812..5194705 Escherichia coli O104:H4 str. 2011C-3493 13700277 YP_006781647.1 CDS O3K_25005 NC_018658.1 5194757 5196301 R COG1171 Threonine dehydratase; threonine dehydratase complement(5194757..5196301) Escherichia coli O104:H4 str. 2011C-3493 13700278 YP_006781648.1 CDS O3K_25010 NC_018658.1 5196304 5198154 R COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxy-acid dehydratase complement(5196304..5198154) Escherichia coli O104:H4 str. 2011C-3493 13700279 YP_006781649.1 CDS O3K_25015 NC_018658.1 5198219 5199148 R COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; branched-chain amino acid aminotransferase complement(5198219..5199148) Escherichia coli O104:H4 str. 2011C-3493 13700280 YP_006781650.1 CDS ilvM NC_018658.1 5199168 5199431 R COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit; acetolactate synthase 2 regulatory subunit complement(5199168..5199431) Escherichia coli O104:H4 str. 2011C-3493 13700281 YP_006781651.1 CDS O3K_25025 NC_018658.1 5199428 5201074 R COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase 2 catalytic subunit complement(5199428..5201074) Escherichia coli O104:H4 str. 2011C-3493 13700282 YP_006781652.1 CDS O3K_25030 NC_018658.1 5201665 5203185 D COG0606 Predicted ATPase with chaperone activity; putative ATP-dependent protease 5201665..5203185 Escherichia coli O104:H4 str. 2011C-3493 13700283 YP_006781653.1 CDS O3K_25035 NC_018658.1 5203210 5203548 R COG3085 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5203210..5203548) Escherichia coli O104:H4 str. 2011C-3493 13700284 YP_006781654.1 CDS O3K_25040 NC_018658.1 5203667 5204506 D COG0583 Transcriptional regulator; transcriptional regulator HdfR 5203667..5204506 Escherichia coli O104:H4 str. 2011C-3493 13700285 YP_006781655.1 CDS O3K_25045 NC_018658.1 5210400 5211092 D COG2186 Transcriptional regulators; transcriptional regulator 5210400..5211092 Escherichia coli O104:H4 str. 2011C-3493 13700293 YP_006781656.1 CDS O3K_25050 NC_018658.1 5211115 5212542 D COG0477 Permeases of the major facilitator superfamily; multidrug or homocysteine efflux system 5211115..5212542 Escherichia coli O104:H4 str. 2011C-3493 13700295 YP_006781657.1 CDS O3K_25055 NC_018658.1 5212508 5213500 R COG1609 Transcriptional regulators; transcriptional repressor RbsR complement(5212508..5213500) Escherichia coli O104:H4 str. 2011C-3493 13700296 YP_006781658.1 CDS O3K_25060 NC_018658.1 5213504 5214433 R COG0524 Sugar kinases, ribokinase family; ribokinase complement(5213504..5214433) Escherichia coli O104:H4 str. 2011C-3493 13700868 YP_006781659.1 CDS O3K_25065 NC_018658.1 5214559 5215449 R COG1879 ABC-type sugar transport system, periplasmic component; D-ribose transporter subunit RbsB complement(5214559..5215449) Escherichia coli O104:H4 str. 2011C-3493 13700869 YP_006781660.1 CDS rbsC NC_018658.1 5215474 5216439 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ribose ABC transporter permease complement(5215474..5216439) Escherichia coli O104:H4 str. 2011C-3493 13700870 YP_006781661.1 CDS O3K_25075 NC_018658.1 5216444 5217949 R COG1129 ABC-type sugar transport system, ATPase component; D-ribose transporter ATP-binding protein complement(5216444..5217949) Escherichia coli O104:H4 str. 2011C-3493 13700871 YP_006781662.1 CDS O3K_25080 NC_018658.1 5217957 5218376 R COG1869 ABC-type ribose transport system, auxiliary component; D-ribose pyranase complement(5217957..5218376) Escherichia coli O104:H4 str. 2011C-3493 13700872 YP_006781663.1 CDS trkD NC_018658.1 5218543 5220411 R COG3158 K+ transporter; potassium transport protein Kup complement(5218543..5220411) Escherichia coli O104:H4 str. 2011C-3493 13700873 YP_006781664.1 CDS O3K_25090 NC_018658.1 5220634 5222130 D COG0714 MoxR-like ATPases; regulatory ATPase RavA 5220634..5222130 Escherichia coli O104:H4 str. 2011C-3493 13700874 YP_006781665.1 CDS O3K_25095 NC_018658.1 5222124 5223575 D COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 5222124..5223575 Escherichia coli O104:H4 str. 2011C-3493 13700875 YP_006781666.1 CDS O3K_25100 NC_018658.1 5223580 5224572 R COG2502 Asparagine synthetase A; asparagine synthetase AsnA complement(5223580..5224572) Escherichia coli O104:H4 str. 2011C-3493 13700876 YP_006781667.1 CDS O3K_25105 NC_018658.1 5224724 5225182 D COG1522 Transcriptional regulators; DNA-binding transcriptional regulator AsnC 5224724..5225182 Escherichia coli O104:H4 str. 2011C-3493 13700877 YP_006781668.1 CDS O3K_25110 NC_018658.1 5225272 5225715 D COG0716 Flavodoxins; FMN-binding protein MioC 5225272..5225715 Escherichia coli O104:H4 str. 2011C-3493 13700878 YP_006781669.1 CDS O3K_25115 NC_018658.1 5226094 5227983 D COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 5226094..5227983 Escherichia coli O104:H4 str. 2011C-3493 13700879 YP_006781670.1 CDS gidB NC_018658.1 5228047 5228670 D COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; 16S rRNA methyltransferase GidB 5228047..5228670 Escherichia coli O104:H4 str. 2011C-3493 13700880 YP_006781671.1 CDS O3K_25125 NC_018658.1 5229287 5229667 D F0F1 ATP synthase subunit I 5229287..5229667 Escherichia coli O104:H4 str. 2011C-3493 13700881 YP_006781672.1 CDS O3K_25130 NC_018658.1 5229676 5230491 D COG0356 F0F1-type ATP synthase, subunit a; F0F1 ATP synthase subunit A 5229676..5230491 Escherichia coli O104:H4 str. 2011C-3493 13700882 YP_006781673.1 CDS O3K_25135 NC_018658.1 5230538 5230777 D COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; F0F1 ATP synthase subunit C 5230538..5230777 Escherichia coli O104:H4 str. 2011C-3493 13700883 YP_006781674.1 CDS O3K_25140 NC_018658.1 5230839 5231309 D COG0711 F0F1-type ATP synthase, subunit b; F0F1 ATP synthase subunit B 5230839..5231309 Escherichia coli O104:H4 str. 2011C-3493 13700884 YP_006781675.1 CDS O3K_25145 NC_018658.1 5231324 5231857 D COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); F0F1 ATP synthase subunit delta 5231324..5231857 Escherichia coli O104:H4 str. 2011C-3493 13700885 YP_006781676.1 CDS O3K_25150 NC_018658.1 5231870 5233411 D COG0056 F0F1-type ATP synthase, alpha subunit; F0F1 ATP synthase subunit alpha 5231870..5233411 Escherichia coli O104:H4 str. 2011C-3493 13700886 YP_006781677.1 CDS O3K_25155 NC_018658.1 5233462 5234325 D COG0224 F0F1-type ATP synthase, gamma subunit; F0F1 ATP synthase subunit gamma 5233462..5234325 Escherichia coli O104:H4 str. 2011C-3493 13700887 YP_006781678.1 CDS O3K_25160 NC_018658.1 5234352 5235734 D COG0055 F0F1-type ATP synthase, beta subunit; F0F1 ATP synthase subunit beta 5234352..5235734 Escherichia coli O104:H4 str. 2011C-3493 13700888 YP_006781679.1 CDS atpC NC_018658.1 5235755 5236174 D COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit); F0F1 ATP synthase subunit epsilon 5235755..5236174 Escherichia coli O104:H4 str. 2011C-3493 13700889 YP_006781680.1 CDS glmU NC_018658.1 5236525 5237895 D COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 5236525..5237895 Escherichia coli O104:H4 str. 2011C-3493 13700890 YP_006781681.1 CDS O3K_25175 NC_018658.1 5238057 5239886 D COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; glucosamine--fructose-6-phosphate aminotransferase 5238057..5239886 Escherichia coli O104:H4 str. 2011C-3493 13700891 YP_006781682.1 CDS lpfA NC_018658.1 5240188 5240760 D COG3539 P pilus assembly protein, pilin FimA; fimbrial protein 5240188..5240760 Escherichia coli O104:H4 str. 2011C-3493 13700892 YP_006781683.1 CDS lfpB NC_018658.1 5240808 5241539 D COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein 5240808..5241539 Escherichia coli O104:H4 str. 2011C-3493 13700893 YP_006781684.1 CDS O3K_25190 NC_018658.1 5241564 5244086 D COG3188 P pilus assembly protein, porin PapC; putative outer membrane usher protein 5241564..5244086 Escherichia coli O104:H4 str. 2011C-3493 13700894 YP_006781685.1 CDS O3K_25195 NC_018658.1 5244097 5245170 D fimbrial protein 5244097..5245170 Escherichia coli O104:H4 str. 2011C-3493 13700895 YP_006781686.1 CDS O3K_25200 NC_018658.1 5245418 5246458 D COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 5245418..5246458 Escherichia coli O104:H4 str. 2011C-3493 13700896 YP_006781687.1 CDS pstC NC_018658.1 5246545 5247504 D COG0573 ABC-type phosphate transport system, permease component; phosphate transporter permease subunit PstC 5246545..5247504 Escherichia coli O104:H4 str. 2011C-3493 13700897 YP_006781688.1 CDS pstA NC_018658.1 5247504 5248394 D COG0581 ABC-type phosphate transport system, permease component; phosphate transporter permease subunit PtsA 5247504..5248394 Escherichia coli O104:H4 str. 2011C-3493 13700898 YP_006781689.1 CDS pstB NC_018658.1 5248485 5249258 D COG1117 ABC-type phosphate transport system, ATPase component; phosphate transporter ATP-binding protein 5248485..5249258 Escherichia coli O104:H4 str. 2011C-3493 13700899 YP_006781690.1 CDS O3K_25220 NC_018658.1 5249273 5249998 D COG0704 Phosphate uptake regulator; transcriptional regulator PhoU 5249273..5249998 Escherichia coli O104:H4 str. 2011C-3493 13700900 YP_006781691.1 CDS O3K_25235 NC_018658.1 5251254 5253131 D COG1264 Phosphotransferase system IIB components; PTS system beta-glucoside-specific transporter subunit IIABC 5251254..5253131 Escherichia coli O104:H4 str. 2011C-3493 13700901 YP_006781692.1 CDS O3K_25240 NC_018658.1 5253150 5254544 D COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; cryptic phospho-beta-glucosidase B 5253150..5254544 Escherichia coli O104:H4 str. 2011C-3493 13700902 YP_006781693.1 CDS O3K_25245 NC_018658.1 5254630 5256246 D COG4580 Maltoporin (phage lambda and maltose receptor); carbohydrate-specific outer membrane porin, cryptic 5254630..5256246 Escherichia coli O104:H4 str. 2011C-3493 13700903 YP_006781694.1 CDS O3K_25250 NC_018658.1 5256273 5257442 D COG2382 Enterochelin esterase and related enzymes; xylanase 5256273..5257442 Escherichia coli O104:H4 str. 2011C-3493 13700904 YP_006781695.1 CDS O3K_25255 NC_018658.1 5257457 5258179 D COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; putative 6-phosphogluconolactonase 5257457..5258179 Escherichia coli O104:H4 str. 2011C-3493 13700905 YP_006781696.1 CDS O3K_25260 NC_018658.1 5258241 5258828 R COG3196 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5258241..5258828) Escherichia coli O104:H4 str. 2011C-3493 13700906 YP_006781697.1 CDS O3K_25265 NC_018658.1 5258877 5259350 R inner membrane protein complement(5258877..5259350) Escherichia coli O104:H4 str. 2011C-3493 13700907 YP_006781698.1 CDS O3K_25270 NC_018658.1 5259417 5260082 R COG0637 Predicted phosphatase/phosphohexomutase; 6-phosphogluconate phosphatase complement(5259417..5260082) Escherichia coli O104:H4 str. 2011C-3493 13700908 YP_006781699.1 CDS O3K_25275 NC_018658.1 5260249 5261586 D COG2252 Permeases; hypothetical protein 5260249..5261586 Escherichia coli O104:H4 str. 2011C-3493 13700909 YP_006781700.1 CDS O3K_25280 NC_018658.1 5261640 5262206 R COG0431 Predicted flavoprotein; hypothetical protein complement(5261640..5262206) Escherichia coli O104:H4 str. 2011C-3493 13700910 YP_006781701.1 CDS O3K_25285 NC_018658.1 5262228 5262977 R COG2091 Phosphopantetheinyl transferase; phosphopantetheinyl transferase complement(5262228..5262977) Escherichia coli O104:H4 str. 2011C-3493 13700911 YP_006781702.1 CDS O3K_25290 NC_018658.1 5263134 5264093 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator YidZ complement(5263134..5264093) Escherichia coli O104:H4 str. 2011C-3493 13700912 YP_006781703.1 CDS O3K_25295 NC_018658.1 5264068 5265243 R COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein MdtL complement(5264068..5265243) Escherichia coli O104:H4 str. 2011C-3493 13700913 YP_006781704.1 CDS O3K_25300 NC_018658.1 5265376 5266623 R COG0814 Amino acid permeases; tryptophan permease TnaB complement(5265376..5266623) Escherichia coli O104:H4 str. 2011C-3493 13700914 YP_006781705.1 CDS tnaA NC_018658.1 5266714 5268129 R COG3033 Tryptophanase; tryptophanase/L-cysteine desulfhydrase, PLP-dependent complement(5266714..5268129) Escherichia coli O104:H4 str. 2011C-3493 13700915 YP_006781706.1 CDS O3K_25310 NC_018658.1 5268350 5268424 R tryptophanase leader peptide complement(5268350..5268424) Escherichia coli O104:H4 str. 2011C-3493 13700916 YP_006781707.1 CDS trmE NC_018658.1 5268667 5270031 R COG0486 Predicted GTPase; tRNA modification GTPase TrmE complement(5268667..5270031) Escherichia coli O104:H4 str. 2011C-3493 13700917 YP_006781708.1 CDS O3K_25320 NC_018658.1 5270137 5271783 R COG0706 Preprotein translocase subunit YidC; membrane protein insertase complement(5270137..5271783) Escherichia coli O104:H4 str. 2011C-3493 13700918 YP_006781709.1 CDS O3K_25325 NC_018658.1 5271786 5272043 R COG0759 Uncharacterized conserved protein; hypothetical protein complement(5271786..5272043) Escherichia coli O104:H4 str. 2011C-3493 13700919 YP_006781710.1 CDS rnpA NC_018658.1 5272007 5272366 R COG0594 RNase P protein component; ribonuclease P complement(5272007..5272366) Escherichia coli O104:H4 str. 2011C-3493 13700920 YP_006781711.1 CDS rpmH NC_018658.1 5272383 5272523 R COG0230 Ribosomal protein L34; 50S ribosomal protein L34 complement(5272383..5272523) Escherichia coli O104:H4 str. 2011C-3493 13700921 YP_006781712.1 CDS O3K_25572 NC_018659.1 86977 1477 R TraU protein complement(join(86977..88544,1..1477)) Escherichia coli O104:H4 str. 2011C-3493 13703856 YP_006781713.1 CDS O3K_25577 NC_018659.1 1567 2367 R TraT transfer protein complement(1567..2367) Escherichia coli O104:H4 str. 2011C-3493 13703764 YP_006781714.1 CDS O3K_25582 NC_018659.1 2351 2539 R TraS transfer protein complement(2351..2539) Escherichia coli O104:H4 str. 2011C-3493 13703857 YP_006781715.1 CDS O3K_25587 NC_018659.1 2603 3007 R hypothetical protein complement(2603..3007) Escherichia coli O104:H4 str. 2011C-3493 13703765 YP_006781716.1 CDS O3K_25592 NC_018659.1 3058 3585 R TraQ protein complement(3058..3585) Escherichia coli O104:H4 str. 2011C-3493 13703766 YP_006781717.1 CDS O3K_25597 NC_018659.1 3585 4289 R hypothetical protein complement(3585..4289) Escherichia coli O104:H4 str. 2011C-3493 13703767 YP_006781718.1 CDS O3K_25602 NC_018659.1 4289 5578 R hypothetical protein complement(4289..5578) Escherichia coli O104:H4 str. 2011C-3493 13703768 YP_006781719.1 CDS O3K_25607 NC_018659.1 5581 6564 R hypothetical protein complement(5581..6564) Escherichia coli O104:H4 str. 2011C-3493 13703769 YP_006781720.1 CDS O3K_25612 NC_018659.1 6575 7267 R TraM protein complement(6575..7267) Escherichia coli O104:H4 str. 2011C-3493 13703770 YP_006781721.1 CDS O3K_25617 NC_018659.1 7264 7611 R F pilus assembly complement(7264..7611) Escherichia coli O104:H4 str. 2011C-3493 13703771 YP_006781722.1 CDS O3K_25622 NC_018659.1 7629 11393 R COG4643 Uncharacterized protein conserved in bacteria; SogL protein complement(7629..11393) Escherichia coli O104:H4 str. 2011C-3493 13703772 YP_006781723.1 CDS O3K_25627 NC_018659.1 11483 12034 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; EDTA-resistant nuclease complement(11483..12034) Escherichia coli O104:H4 str. 2011C-3493 13703773 YP_006781724.1 CDS O3K_25632 NC_018659.1 12336 13484 R COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT; TraJ transfer ATPase complement(12336..13484) Escherichia coli O104:H4 str. 2011C-3493 13703774 YP_006781725.1 CDS O3K_25637 NC_018659.1 13481 14299 R lipoprotein complement(13481..14299) Escherichia coli O104:H4 str. 2011C-3493 13703775 YP_006781726.1 CDS O3K_25642 NC_018659.1 14296 14754 R TraH lipoprotein complement(14296..14754) Escherichia coli O104:H4 str. 2011C-3493 13703776 YP_006781727.1 CDS O3K_25647 NC_018659.1 15149 15733 R lipopolysaccharide core heptose(II)-phosphate phosphatase complement(15149..15733) Escherichia coli O104:H4 str. 2011C-3493 13703777 YP_006781728.1 CDS O3K_25652 NC_018659.1 15793 16995 R F pilus assembly complement(15793..16995) Escherichia coli O104:H4 str. 2011C-3493 13703778 YP_006781729.1 CDS O3K_25657 NC_018659.1 17081 17905 R COG0457 FOG: TPR repeat; F pilus assembly complement(17081..17905) Escherichia coli O104:H4 str. 2011C-3493 13703779 YP_006781730.1 CDS O3K_25662 NC_018659.1 18056 19210 R COG0582 Integrase; shufflon-specific DNA recombinase complement(18056..19210) Escherichia coli O104:H4 str. 2011C-3493 13703780 YP_006781731.1 CDS O3K_25667 NC_018659.1 20231 20350 D putative PilVB C-terminal segment; hypothetical protein 20231..20350 Escherichia coli O104:H4 str. 2011C-3493 13703781 YP_006781732.1 CDS O3K_25672 NC_018659.1 20375 20581 R hypothetical protein complement(20375..20581) Escherichia coli O104:H4 str. 2011C-3493 13703782 YP_006781733.1 CDS O3K_25677 NC_018659.1 20844 22280 R shufflon protein A complement(20844..22280) Escherichia coli O104:H4 str. 2011C-3493 13703783 YP_006781734.1 CDS O3K_25682 NC_018659.1 22268 22924 R COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; PilU prepilin peptidase complement(22268..22924) Escherichia coli O104:H4 str. 2011C-3493 13703784 YP_006781735.1 CDS O3K_25687 NC_018659.1 22909 23469 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); type IV prepilin cluster complement(22909..23469) Escherichia coli O104:H4 str. 2011C-3493 13703785 YP_006781736.1 CDS O3K_25692 NC_018659.1 23479 24093 R type IV prepilin cluster, prepilin complement(23479..24093) Escherichia coli O104:H4 str. 2011C-3493 13703786 YP_006781737.1 CDS O3K_25697 NC_018659.1 24110 25195 R COG1459 Type II secretory pathway, component PulF; putative transmembrane protein complement(24110..25195) Escherichia coli O104:H4 str. 2011C-3493 13703787 YP_006781738.1 CDS O3K_25702 NC_018659.1 25208 26761 R COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; type IV prepilin cluster, ATP-binding protein complement(25208..26761) Escherichia coli O104:H4 str. 2011C-3493 13703788 YP_006781739.1 CDS O3K_25707 NC_018659.1 26772 27224 R putative conjugative transfer PilP protein complement(26772..27224) Escherichia coli O104:H4 str. 2011C-3493 13703789 YP_006781740.1 CDS O3K_25712 NC_018659.1 27211 28506 R PilO protein complement(27211..28506) Escherichia coli O104:H4 str. 2011C-3493 13703790 YP_006781741.1 CDS O3K_25717 NC_018659.1 28499 30181 R COG1450 Type II secretory pathway, component PulD; PilN type IV pilus secretin complement(28499..30181) Escherichia coli O104:H4 str. 2011C-3493 13703791 YP_006781742.1 CDS O3K_25722 NC_018659.1 30195 30632 R PilM type IV pilus biogenesis protein complement(30195..30632) Escherichia coli O104:H4 str. 2011C-3493 13703792 YP_006781743.1 CDS O3K_25727 NC_018659.1 30632 31699 R lipoprotein PilL complement(30632..31699) Escherichia coli O104:H4 str. 2011C-3493 13703793 YP_006781744.1 CDS O3K_25732 NC_018659.1 32746 33045 R hypothetical protein complement(32746..33045) Escherichia coli O104:H4 str. 2011C-3493 13703794 YP_006781745.1 CDS O3K_25737 NC_018659.1 33172 33855 R TraC complement(33172..33855) Escherichia coli O104:H4 str. 2011C-3493 13703795 YP_006781746.1 CDS O3K_25742 NC_018659.1 34109 34642 R COG0250 Transcription antiterminator; TraB protein complement(34109..34642) Escherichia coli O104:H4 str. 2011C-3493 13703796 YP_006781747.1 CDS O3K_25747 NC_018659.1 35084 35371 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; protein TraA complement(35084..35371) Escherichia coli O104:H4 str. 2011C-3493 13703797 YP_006781748.1 CDS O3K_25752 NC_018659.1 35289 35552 R hypothetical protein complement(35289..35552) Escherichia coli O104:H4 str. 2011C-3493 13703798 YP_006781749.1 CDS O3K_25757 NC_018659.1 36525 37556 D COG1132 ABC-type multidrug transport system, ATPase and permease components; replication initiation protein 36525..37556 Escherichia coli O104:H4 str. 2011C-3493 13703799 YP_006781750.1 CDS O3K_25762 NC_018659.1 38626 39135 R protein YafA complement(38626..39135) Escherichia coli O104:H4 str. 2011C-3493 13703800 YP_006781751.1 CDS O3K_25767 NC_018659.1 39191 39793 R COG3109 Activator of osmoprotectant transporter ProP; hypothetical protein complement(39191..39793) Escherichia coli O104:H4 str. 2011C-3493 13703801 YP_006781752.1 CDS O3K_25772 NC_018659.1 40146 41492 D hypothetical protein 40146..41492 Escherichia coli O104:H4 str. 2011C-3493 13703802 YP_006781753.1 CDS O3K_25777 NC_018659.1 41980 44454 R COG4644 Transposase and inactivated derivatives, TnpA family; hypothetical protein complement(41980..44454) Escherichia coli O104:H4 str. 2011C-3493 13703803 YP_006781754.1 CDS O3K_25782 NC_018659.1 44849 45121 D hypothetical protein 44849..45121 Escherichia coli O104:H4 str. 2011C-3493 13703804 YP_006781755.1 CDS O3K_25787 NC_018659.1 45168 46043 R COG2367 Beta-lactamase class A; beta-lactamase complement(45168..46043) Escherichia coli O104:H4 str. 2011C-3493 13703805 YP_006781756.1 CDS O3K_25792 NC_018659.1 46196 46318 R hypothetical protein complement(46196..46318) Escherichia coli O104:H4 str. 2011C-3493 13703806 YP_006781757.1 CDS O3K_25797 NC_018659.1 46299 47561 R ISEcp1 transposase complement(46299..47561) Escherichia coli O104:H4 str. 2011C-3493 13703807 YP_006781758.1 CDS O3K_25802 NC_018659.1 47743 47961 R COG4644 Transposase and inactivated derivatives, TnpA family; transposase complement(47743..47961) Escherichia coli O104:H4 str. 2011C-3493 13703808 YP_006781759.1 CDS O3K_25807 NC_018659.1 48125 48682 D COG1961 Site-specific recombinases, DNA invertase Pin homologs; Tn3 resolvase 48125..48682 Escherichia coli O104:H4 str. 2011C-3493 13703809 YP_006781760.1 CDS O3K_25812 NC_018659.1 48865 49725 D COG2367 Beta-lactamase class A; beta-lactamase TEM 48865..49725 Escherichia coli O104:H4 str. 2011C-3493 13703810 YP_006781761.1 CDS O3K_25817 NC_018659.1 49994 50296 R hypothetical protein complement(49994..50296) Escherichia coli O104:H4 str. 2011C-3493 13703811 YP_006781762.1 CDS O3K_25822 NC_018659.1 50293 50826 R COG1192 ATPases involved in chromosome partitioning; Type II plasmid partioning protein complement(50293..50826) Escherichia coli O104:H4 str. 2011C-3493 13703812 YP_006781763.1 CDS umuC NC_018659.1 51123 52394 R COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC complement(51123..52394) Escherichia coli O104:H4 str. 2011C-3493 13703813 YP_006781764.1 CDS O3K_25832 NC_018659.1 52394 52831 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); DNA polymerase V subunit ImpA complement(52394..52831) Escherichia coli O104:H4 str. 2011C-3493 13703814 YP_006781765.1 CDS O3K_25837 NC_018659.1 52828 53076 R hypothetical protein complement(52828..53076) Escherichia coli O104:H4 str. 2011C-3493 13703815 YP_006781766.1 CDS O3K_25842 NC_018659.1 53471 54397 D hypothetical protein 53471..54397 Escherichia coli O104:H4 str. 2011C-3493 13703816 YP_006781767.1 CDS O3K_25847 NC_018659.1 54782 55465 D COG0863 DNA modification methylase; putative methylase 54782..55465 Escherichia coli O104:H4 str. 2011C-3493 13703817 YP_006781768.1 CDS O3K_25852 NC_018659.1 55466 55687 D hypothetical protein 55466..55687 Escherichia coli O104:H4 str. 2011C-3493 13703818 YP_006781769.1 CDS O3K_25857 NC_018659.1 55701 56135 D hypothetical protein 55701..56135 Escherichia coli O104:H4 str. 2011C-3493 13703819 YP_006781770.1 CDS O3K_25862 NC_018659.1 56181 56957 D YchA 56181..56957 Escherichia coli O104:H4 str. 2011C-3493 13703820 YP_006781771.1 CDS O3K_25867 NC_018659.1 57371 57796 D COG0587 DNA polymerase III, alpha subunit; antirestriction protein 57371..57796 Escherichia coli O104:H4 str. 2011C-3493 13703821 YP_006781772.1 CDS O3K_25872 NC_018659.1 57843 58265 D hypothetical protein 57843..58265 Escherichia coli O104:H4 str. 2011C-3493 13703822 YP_006781773.1 CDS O3K_25877 NC_018659.1 58262 58453 D hypothetical protein 58262..58453 Escherichia coli O104:H4 str. 2011C-3493 13703823 YP_006781774.1 CDS O3K_25882 NC_018659.1 59222 59749 D COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein 59222..59749 Escherichia coli O104:H4 str. 2011C-3493 13703824 YP_006781775.1 CDS O3K_25887 NC_018659.1 59807 60040 D hypothetical protein 59807..60040 Escherichia coli O104:H4 str. 2011C-3493 13703825 YP_006781776.1 CDS O3K_25892 NC_018659.1 60099 62057 D COG1475 Predicted transcriptional regulators; Type II plasmid partioning protein 60099..62057 Escherichia coli O104:H4 str. 2011C-3493 13703826 YP_006781777.1 CDS psiB NC_018659.1 62112 62546 D plasmid SOS inhibition protein B 62112..62546 Escherichia coli O104:H4 str. 2011C-3493 13703827 YP_006781778.1 CDS O3K_25902 NC_018659.1 62543 63262 D plasmid SOS inhibition protein A 62543..63262 Escherichia coli O104:H4 str. 2011C-3493 13703828 YP_006781779.1 CDS O3K_25907 NC_018659.1 63259 63855 D YgaA 63259..63855 Escherichia coli O104:H4 str. 2011C-3493 13703829 YP_006781780.1 CDS O3K_25912 NC_018659.1 64317 64817 D COG4734 Antirestriction protein; anti-restriction protein 64317..64817 Escherichia coli O104:H4 str. 2011C-3493 13703830 YP_006781781.1 CDS O3K_25917 NC_018659.1 65546 65980 D hypothetical protein 65546..65980 Escherichia coli O104:H4 str. 2011C-3493 13703831 YP_006781782.1 CDS O3K_25922 NC_018659.1 66074 66340 D hypothetical protein 66074..66340 Escherichia coli O104:H4 str. 2011C-3493 13703832 YP_006781783.1 CDS O3K_25927 NC_018659.1 66517 66906 D hypothetical protein 66517..66906 Escherichia coli O104:H4 str. 2011C-3493 13703833 YP_006781784.1 CDS O3K_25932 NC_018659.1 66903 67817 D COG5464 Uncharacterized conserved protein; hypothetical protein 66903..67817 Escherichia coli O104:H4 str. 2011C-3493 13703834 YP_006781785.1 CDS O3K_25937 NC_018659.1 67879 68085 D COG5464 Uncharacterized conserved protein; hypothetical protein 67879..68085 Escherichia coli O104:H4 str. 2011C-3493 13703835 YP_006781786.1 CDS O3K_25942 NC_018659.1 68116 68367 R hypothetical protein complement(68116..68367) Escherichia coli O104:H4 str. 2011C-3493 13703836 YP_006781787.1 CDS O3K_25947 NC_018659.1 68947 69795 D hypothetical protein 68947..69795 Escherichia coli O104:H4 str. 2011C-3493 13703837 YP_006781788.1 CDS O3K_25952 NC_018659.1 69882 70217 R protein YggA complement(69882..70217) Escherichia coli O104:H4 str. 2011C-3493 13703838 YP_006781789.1 CDS O3K_25957 NC_018659.1 70451 70783 D relaxosome component 70451..70783 Escherichia coli O104:H4 str. 2011C-3493 13703839 YP_006781790.1 CDS O3K_25962 NC_018659.1 70794 73493 D relaxase 70794..73493 Escherichia coli O104:H4 str. 2011C-3493 13703840 YP_006781791.1 CDS O3K_25967 NC_018659.1 73530 75821 R IcmO-like type IV secretion system protein complement(73530..75821) Escherichia coli O104:H4 str. 2011C-3493 13703841 YP_006781792.1 CDS O3K_25972 NC_018659.1 75814 76884 R COG1651 Protein-disulfide isomerase; hypothetical protein complement(75814..76884) Escherichia coli O104:H4 str. 2011C-3493 13703842 YP_006781793.1 CDS O3K_25977 NC_018659.1 76903 78111 R hypothetical protein complement(76903..78111) Escherichia coli O104:H4 str. 2011C-3493 13703843 YP_006781794.1 CDS O3K_25982 NC_018659.1 78418 79503 R fertility inhibition protein complement(78418..79503) Escherichia coli O104:H4 str. 2011C-3493 13703844 YP_006781795.1 CDS O3K_25987 NC_018659.1 79821 79976 D hypothetical protein 79821..79976 Escherichia coli O104:H4 str. 2011C-3493 13703845 YP_006781796.1 CDS O3K_25992 NC_018659.1 80048 80299 R hypothetical protein complement(80048..80299) Escherichia coli O104:H4 str. 2011C-3493 13703846 YP_006781797.1 CDS O3K_25997 NC_018659.1 80599 80895 D hypothetical protein 80599..80895 Escherichia coli O104:H4 str. 2011C-3493 13703847 YP_006781798.1 CDS O3K_26002 NC_018659.1 80960 81136 R hypothetical protein complement(80960..81136) Escherichia coli O104:H4 str. 2011C-3493 13703848 YP_006781799.1 CDS O3K_26007 NC_018659.1 81133 81276 R hypothetical protein complement(81133..81276) Escherichia coli O104:H4 str. 2011C-3493 13703849 YP_006781800.1 CDS O3K_26012 NC_018659.1 81319 81528 R putative regulator protein complement(81319..81528) Escherichia coli O104:H4 str. 2011C-3493 13703850 YP_006781801.1 CDS O3K_26017 NC_018659.1 81626 82240 R surface exclusion protein complement(81626..82240) Escherichia coli O104:H4 str. 2011C-3493 13703851 YP_006781802.1 CDS O3K_26022 NC_018659.1 82316 84553 R TraY integral membrane protein complement(82316..84553) Escherichia coli O104:H4 str. 2011C-3493 13703852 YP_006781803.1 CDS O3K_26027 NC_018659.1 84581 85165 R F pilin acetylation protein complement(84581..85165) Escherichia coli O104:H4 str. 2011C-3493 13703853 YP_006781804.1 CDS O3K_26032 NC_018659.1 85194 86396 R F pilus assembly complement(85194..86396) Escherichia coli O104:H4 str. 2011C-3493 13703854 YP_006781805.1 CDS O3K_26037 NC_018659.1 86363 86977 R F pilus assembly complement(86363..86977) Escherichia coli O104:H4 str. 2011C-3493 13703855 YP_006781806.1 CDS O3K_26522 NC_018660.1 1313 240 D plasmid replication protein join(1313..1549,1..240) Escherichia coli O104:H4 str. 2011C-3493 13703859 YP_006792544.1 CDS O3K_26057 NC_018666.1 757 1737 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase complement(757..1737) Escherichia coli O104:H4 str. 2011C-3493 13715097 YP_006792545.1 CDS O3K_26062 NC_018666.1 1736 1870 D hypothetical protein 1736..1870 Escherichia coli O104:H4 str. 2011C-3493 13715016 YP_006792546.1 CDS O3K_26077 NC_018666.1 3211 4734 R COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein, CP4-6 prophage (modular protein) complement(3211..4734) Escherichia coli O104:H4 str. 2011C-3493 13715017 YP_006792547.1 CDS O3K_26087 NC_018666.1 5805 6131 R COG2963 Transposase and inactivated derivatives; IS629 protein complement(5805..6131) Escherichia coli O104:H4 str. 2011C-3493 13715019 YP_006792548.1 CDS O3K_26097 NC_018666.1 6865 7662 D COG2207 AraC-type DNA-binding domain-containing proteins; putative transcriptional activator aggR (AAF-III) regulatory protein 6865..7662 Escherichia coli O104:H4 str. 2011C-3493 13715020 YP_006792549.1 CDS O3K_26102 NC_018666.1 7763 8167 D COG3677 Transposase and inactivated derivatives; IS1; transposase ORF A, IS1 7763..8167 Escherichia coli O104:H4 str. 2011C-3493 13715021 YP_006792550.1 CDS O3K_26107 NC_018666.1 8410 9234 R COG3547 Transposase and inactivated derivatives; transposase complement(8410..9234) Escherichia coli O104:H4 str. 2011C-3493 13715022 YP_006792551.1 CDS O3K_26112 NC_018666.1 9596 10576 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase complement(9596..10576) Escherichia coli O104:H4 str. 2011C-3493 13715023 YP_006792552.1 CDS O3K_26117 NC_018666.1 10575 10736 D hypothetical protein 10575..10736 Escherichia coli O104:H4 str. 2011C-3493 13715024 YP_006792553.1 CDS O3K_26122 NC_018666.1 10736 10888 D hypothetical protein 10736..10888 Escherichia coli O104:H4 str. 2011C-3493 13715025 YP_006792554.1 CDS O3K_26127 NC_018666.1 11391 11678 R IPP:Isopentenyl pyrophosphate isomerase; IPP:DMAPP isomerase; COG1443 Isopentenyldiphosphate isomerase; putative Isopentenyl-diphosphate delta-isomerase complement(11391..11678) Escherichia coli O104:H4 str. 2011C-3493 13715026 YP_006792555.1 CDS O3K_26132 NC_018666.1 11687 11911 R hypothetical protein complement(11687..11911) Escherichia coli O104:H4 str. 2011C-3493 13715027 YP_006792556.1 CDS O3K_26137 NC_018666.1 11934 12962 R hypothetical protein complement(11934..12962) Escherichia coli O104:H4 str. 2011C-3493 13715028 YP_006792557.1 CDS O3K_26147 NC_018666.1 13398 13898 D COG2963 Transposase and inactivated derivatives; putative ISRSO11-transposase orfA protein 13398..13898 Escherichia coli O104:H4 str. 2011C-3493 13715029 YP_006792558.1 CDS O3K_26152 NC_018666.1 14141 14329 D COG2801 Transposase and inactivated derivatives; IS150 ORF B; transposase 14141..14329 Escherichia coli O104:H4 str. 2011C-3493 13715030 YP_006792559.1 CDS O3K_26157 NC_018666.1 14354 14578 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(14354..14578) Escherichia coli O104:H4 str. 2011C-3493 13715031 YP_006792560.1 CDS O3K_26162 NC_018666.1 14623 14880 D COG2801 Transposase and inactivated derivatives; ISEhe3 orfB 14623..14880 Escherichia coli O104:H4 str. 2011C-3493 13715032 YP_006792561.1 CDS O3K_26177 NC_018666.1 16503 16850 R COG3436 Transposase and inactivated derivatives; putative transposase complement(16503..16850) Escherichia coli O104:H4 str. 2011C-3493 13715033 YP_006792562.1 CDS O3K_26182 NC_018666.1 16847 17248 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(16847..17248) Escherichia coli O104:H4 str. 2011C-3493 13715034 YP_006792563.1 CDS O3K_26187 NC_018666.1 17434 17595 D COG3464 Transposase and inactivated derivatives; hypothetical protein 17434..17595 Escherichia coli O104:H4 str. 2011C-3493 13715035 YP_006792564.1 CDS O3K_26192 NC_018666.1 17564 17884 R COG4584 Transposase and inactivated derivatives; putative transposase complement(17564..17884) Escherichia coli O104:H4 str. 2011C-3493 13715036 YP_006792565.1 CDS O3K_26197 NC_018666.1 18021 18524 R hypothetical protein complement(18021..18524) Escherichia coli O104:H4 str. 2011C-3493 13715037 YP_006792566.1 CDS O3K_26202 NC_018666.1 18626 19063 R Protein Agg3B, putative invasin complement(18626..19063) Escherichia coli O104:H4 str. 2011C-3493 13715038 YP_006792567.1 CDS O3K_26207 NC_018666.1 19077 21461 R COG3188 P pilus assembly protein, porin PapC; Outer membrane usher protein Agg3C complement(19077..21461) Escherichia coli O104:H4 str. 2011C-3493 13715039 YP_006792568.1 CDS O3K_26212 NC_018666.1 21619 22248 R COG3121 P pilus assembly protein, chaperone PapD; Chaperone protein Agg3D complement(21619..22248) Escherichia coli O104:H4 str. 2011C-3493 13715040 YP_006792569.1 CDS O3K_26217 NC_018666.1 22524 22727 R hypothetical protein complement(22524..22727) Escherichia coli O104:H4 str. 2011C-3493 13715041 YP_006792570.1 CDS O3K_26222 NC_018666.1 23226 23837 R COG1961 Site-specific recombinases, DNA invertase Pin homologs; Resolvase complement(23226..23837) Escherichia coli O104:H4 str. 2011C-3493 13715042 YP_006792571.1 CDS O3K_26227 NC_018666.1 23924 24301 D COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); putative UV protection protein 23924..24301 Escherichia coli O104:H4 str. 2011C-3493 13715043 YP_006792572.1 CDS umuC NC_018666.1 24301 25497 D COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC 24301..25497 Escherichia coli O104:H4 str. 2011C-3493 13715044 YP_006792573.1 CDS O3K_26237 NC_018666.1 25577 25993 R hypothetical protein complement(25577..25993) Escherichia coli O104:H4 str. 2011C-3493 13715045 YP_006792574.1 CDS O3K_26242 NC_018666.1 25986 26966 R COG0443 Molecular chaperone; Plasmid segregation protein (ParA locus) complement(25986..26966) Escherichia coli O104:H4 str. 2011C-3493 13715046 YP_006792575.1 CDS O3K_26247 NC_018666.1 27380 27688 R putative chaperonin complement(27380..27688) Escherichia coli O104:H4 str. 2011C-3493 13715047 YP_006792576.1 CDS O3K_26252 NC_018666.1 27775 28419 R COG1192 ATPases involved in chromosome partitioning; ATPase involved in chromosome partitioning complement(27775..28419) Escherichia coli O104:H4 str. 2011C-3493 13715048 YP_006792577.1 CDS O3K_26257 NC_018666.1 28598 29404 R COG0582 Integrase; putative resolvase complement(28598..29404) Escherichia coli O104:H4 str. 2011C-3493 13715049 YP_006792578.1 CDS O3K_26262 NC_018666.1 29405 29710 R plasmid maintenance protein CcdB complement(29405..29710) Escherichia coli O104:H4 str. 2011C-3493 13715050 YP_006792579.1 CDS O3K_26267 NC_018666.1 29712 29930 R COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid; plasmid maintenance protein CcdA complement(29712..29930) Escherichia coli O104:H4 str. 2011C-3493 13715051 YP_006792580.1 CDS O3K_26272 NC_018666.1 30525 30755 D COG4456 Virulence-associated protein and related proteins; hypothetical protein 30525..30755 Escherichia coli O104:H4 str. 2011C-3493 13715052 YP_006792581.1 CDS O3K_26277 NC_018666.1 30752 31180 D COG1487 Predicted nucleic acid-binding protein, contains PIN domain; hypothetical protein 30752..31180 Escherichia coli O104:H4 str. 2011C-3493 13715053 YP_006792582.1 CDS O3K_26282 NC_018666.1 31263 31418 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(31263..31418) Escherichia coli O104:H4 str. 2011C-3493 13715054 YP_006792583.1 CDS O3K_26287 NC_018666.1 32504 33481 D putative RepFIB replication protein A 32504..33481 Escherichia coli O104:H4 str. 2011C-3493 13715055 YP_006792584.1 CDS O3K_26292 NC_018666.1 33760 34500 R COG0582 Integrase; putative resolvase (protein D) complement(33760..34500) Escherichia coli O104:H4 str. 2011C-3493 13715056 YP_006792585.1 CDS O3K_26297 NC_018666.1 34869 34955 R hypothetical protein complement(34869..34955) Escherichia coli O104:H4 str. 2011C-3493 13715057 YP_006792586.1 CDS O3K_26302 NC_018666.1 35232 35477 R COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain; hypothetical protein complement(35232..35477) Escherichia coli O104:H4 str. 2011C-3493 13715058 YP_006792587.1 CDS O3K_26307 NC_018666.1 35483 35758 R COG3668 Plasmid stabilization system protein; hypothetical protein complement(35483..35758) Escherichia coli O104:H4 str. 2011C-3493 13715059 YP_006792588.1 CDS O3K_26312 NC_018666.1 35758 36042 R hypothetical protein complement(35758..36042) Escherichia coli O104:H4 str. 2011C-3493 13715060 YP_006792589.1 CDS O3K_26317 NC_018666.1 36950 37621 R replication protein complement(36950..37621) Escherichia coli O104:H4 str. 2011C-3493 13715061 YP_006792590.1 CDS O3K_26322 NC_018666.1 37590 37778 R replication protein complement(37590..37778) Escherichia coli O104:H4 str. 2011C-3493 13715062 YP_006792591.1 CDS O3K_26327 NC_018666.1 37771 37845 R leader peptide RepL complement(37771..37845) Escherichia coli O104:H4 str. 2011C-3493 13715063 YP_006792592.1 CDS O3K_26332 NC_018666.1 38083 38337 R replication protein complement(38083..38337) Escherichia coli O104:H4 str. 2011C-3493 13715064 YP_006792593.1 CDS O3K_26337 NC_018666.1 38618 39598 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 38618..39598 Escherichia coli O104:H4 str. 2011C-3493 13715065 YP_006792594.1 CDS O3K_26342 NC_018666.1 40006 40176 R hypothetical protein complement(40006..40176) Escherichia coli O104:H4 str. 2011C-3493 13715066 YP_006792595.1 CDS O3K_26347 NC_018666.1 40326 41003 D COG4584 Transposase and inactivated derivatives; IS66 family transposase orfA 40326..41003 Escherichia coli O104:H4 str. 2011C-3493 13715067 YP_006792596.1 CDS O3K_26352 NC_018666.1 41003 41350 D COG3436 Transposase and inactivated derivatives; IS66 family element, orf2 41003..41350 Escherichia coli O104:H4 str. 2011C-3493 13715068 YP_006792597.1 CDS O3K_26357 NC_018666.1 41370 42941 D COG3436 Transposase and inactivated derivatives; hypothetical protein 41370..42941 Escherichia coli O104:H4 str. 2011C-3493 13715069 YP_006792598.1 CDS O3K_26362 NC_018666.1 42995 43180 R COG3436 Transposase and inactivated derivatives; putative transposase complement(42995..43180) Escherichia coli O104:H4 str. 2011C-3493 13715070 YP_006792599.1 CDS O3K_26367 NC_018666.1 43254 43550 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(43254..43550) Escherichia coli O104:H4 str. 2011C-3493 13715071 YP_006792600.1 CDS O3K_26372 NC_018666.1 43547 43981 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(43547..43981) Escherichia coli O104:H4 str. 2011C-3493 13715072 YP_006792601.1 CDS O3K_26377 NC_018666.1 44210 44770 R conjugal transfer fertility inhibition protein FinO complement(44210..44770) Escherichia coli O104:H4 str. 2011C-3493 13715073 YP_006792602.1 CDS O3K_26382 NC_018666.1 44825 45571 R conjugal transfer pilus acetylation protein TraX complement(44825..45571) Escherichia coli O104:H4 str. 2011C-3493 13715074 YP_006792603.1 CDS O3K_26387 NC_018666.1 45591 45728 R conjugal transfer nickase/helicase TraI complement(45591..45728) Escherichia coli O104:H4 str. 2011C-3493 13715075 YP_006792604.1 CDS O3K_26392 NC_018666.1 45804 49517 R COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; conjugal transfer nickase/helicase TraI complement(45804..49517) Escherichia coli O104:H4 str. 2011C-3493 13715076 YP_006792605.1 CDS O3K_26397 NC_018666.1 49522 50196 R COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; conjugal transfer nickase/helicase TraI complement(49522..50196) Escherichia coli O104:H4 str. 2011C-3493 13715077 YP_006792606.1 CDS O3K_26402 NC_018666.1 50318 50617 D COG3677 Transposase and inactivated derivatives; IS1 orfA 50318..50617 Escherichia coli O104:H4 str. 2011C-3493 13715078 YP_006792607.1 CDS O3K_26412 NC_018666.1 51661 52044 R COG1082 Sugar phosphate isomerases/epimerases; conjugal transfer protein TraM complement(51661..52044) Escherichia coli O104:H4 str. 2011C-3493 13715080 YP_006792608.1 CDS O3K_26417 NC_018666.1 52468 52977 D COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic transglycosylase 52468..52977 Escherichia coli O104:H4 str. 2011C-3493 13715081 YP_006792609.1 CDS O3K_26422 NC_018666.1 53295 54095 R YubP complement(53295..54095) Escherichia coli O104:H4 str. 2011C-3493 13715082 YP_006792610.1 CDS O3K_26427 NC_018666.1 54890 55147 D COG1961 Site-specific recombinases, DNA invertase Pin homologs; putative recombinase 54890..55147 Escherichia coli O104:H4 str. 2011C-3493 13715083 YP_006792611.1 CDS O3K_26432 NC_018666.1 55669 59763 D COG3468 Type V secretory pathway, adhesin AidA; protease IgA1 55669..59763 Escherichia coli O104:H4 str. 2011C-3493 13715084 YP_006792612.1 CDS O3K_26437 NC_018666.1 60058 60243 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(60058..60243) Escherichia coli O104:H4 str. 2011C-3493 13715085 YP_006792613.1 CDS O3K_26442 NC_018666.1 60357 60791 D COG2963 Transposase and inactivated derivatives; hypothetical protein 60357..60791 Escherichia coli O104:H4 str. 2011C-3493 13715086 YP_006792614.1 CDS O3K_26447 NC_018666.1 60788 61138 D COG3436 Transposase and inactivated derivatives; hypothetical protein 60788..61138 Escherichia coli O104:H4 str. 2011C-3493 13715087 YP_006792615.1 CDS O3K_26452 NC_018666.1 61169 62668 D COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF1, IS66 family protein 61169..62668 Escherichia coli O104:H4 str. 2011C-3493 13715088 YP_006792616.1 CDS O3K_26457 NC_018666.1 62938 63978 R COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein complement(62938..63978) Escherichia coli O104:H4 str. 2011C-3493 13715089 YP_006792617.1 CDS O3K_26462 NC_018666.1 64953 66164 R COG0815 Apolipoprotein N-acyltransferase; AatD complement(64953..66164) Escherichia coli O104:H4 str. 2011C-3493 13715090 YP_006792618.1 CDS O3K_26467 NC_018666.1 66181 66810 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; AatC ATB binding protein of ABC transporter complement(66181..66810) Escherichia coli O104:H4 str. 2011C-3493 13715091 YP_006792619.1 CDS O3K_26472 NC_018666.1 66803 67441 R AatB complement(66803..67441) Escherichia coli O104:H4 str. 2011C-3493 13715092 YP_006792620.1 CDS O3K_26477 NC_018666.1 67521 68759 R AatA outermembrane protein complement(67521..68759) Escherichia coli O104:H4 str. 2011C-3493 13715093 YP_006792621.1 CDS O3K_26482 NC_018666.1 68756 69886 R COG0577 ABC-type antimicrobial peptide transport system, permease component; AatP permease complement(68756..69886) Escherichia coli O104:H4 str. 2011C-3493 13715094 YP_006792622.1 CDS O3K_26492 NC_018666.1 70508 70600 D ISSfl4 ORF3; transposase 70508..70600 Escherichia coli O104:H4 str. 2011C-3493 13715095 YP_006792623.1 CDS O3K_26497 NC_018666.1 70657 70893 D COG2963 Transposase and inactivated derivatives; hypothetical protein 70657..70893 Escherichia coli O104:H4 str. 2011C-3493 13715096 O3K_t25342 tRNA O3K_t25342 NC_018658.1 93883 93977 R tRNA-Sec complement(93883..93977) Escherichia coli O104:H4 str. 2011C-3493 13698779 O3K_t25344 tRNA O3K_t25344 NC_018658.1 229466 229542 D tRNA-Pro 229466..229542 Escherichia coli O104:H4 str. 2011C-3493 13698899 O3K_t25346 tRNA O3K_t25346 NC_018658.1 526391 526467 D tRNA-Ile 526391..526467 Escherichia coli O104:H4 str. 2011C-3493 13699187 O3K_t25348 tRNA O3K_t25348 NC_018658.1 526510 526585 D tRNA-Ala 526510..526585 Escherichia coli O104:H4 str. 2011C-3493 13699188 O3K_t25350 tRNA O3K_t25350 NC_018658.1 529899 529974 D tRNA-Thr 529899..529974 Escherichia coli O104:H4 str. 2011C-3493 13699191 O3K_t25352 tRNA O3K_t25352 NC_018658.1 623633 623719 D tRNA-Leu 623633..623719 Escherichia coli O104:H4 str. 2011C-3493 13699285 O3K_t25354 tRNA O3K_t25354 NC_018658.1 627500 627576 D tRNA-Met 627500..627576 Escherichia coli O104:H4 str. 2011C-3493 13699288 O3K_t25356 tRNA O3K_t25356 NC_018658.1 738754 738829 R tRNA-Met complement(738754..738829) Escherichia coli O104:H4 str. 2011C-3493 13700399 O3K_t25358 tRNA O3K_t25358 NC_018658.1 944314 944389 R tRNA-Phe complement(944314..944389) Escherichia coli O104:H4 str. 2011C-3493 13700591 O3K_t25360 tRNA O3K_t25360 NC_018658.1 1059754 1059827 D tRNA-Gly 1059754..1059827 Escherichia coli O104:H4 str. 2011C-3493 13700698 O3K_t25362 tRNA O3K_t25362 NC_018658.1 1118117 1118193 R tRNA-Met complement(1118117..1118193) Escherichia coli O104:H4 str. 2011C-3493 13700752 O3K_t25364 tRNA O3K_t25364 NC_018658.1 1253707 1253799 D tRNA-Ser 1253707..1253799 Escherichia coli O104:H4 str. 2011C-3493 13702672 O3K_t25366 tRNA O3K_t25366 NC_018658.1 1253803 1253879 D tRNA-Arg 1253803..1253879 Escherichia coli O104:H4 str. 2011C-3493 13702673 O3K_t25368 tRNA O3K_t25368 NC_018658.1 1254076 1254152 D tRNA-Arg 1254076..1254152 Escherichia coli O104:H4 str. 2011C-3493 13702674 O3K_t25370 tRNA O3K_t25370 NC_018658.1 1286179 1286254 D tRNA-Met 1286179..1286254 Escherichia coli O104:H4 str. 2011C-3493 13702708 O3K_t25372 tRNA O3K_t25372 NC_018658.1 1329940 1330015 D tRNA-Glu 1329940..1330015 Escherichia coli O104:H4 str. 2011C-3493 13702745 O3K_t25374 tRNA O3K_t25374 NC_018658.1 1530274 1530349 R tRNA-Lys complement(1530274..1530349) Escherichia coli O104:H4 str. 2011C-3493 13702933 O3K_t25376 tRNA O3K_t25376 NC_018658.1 1530354 1530429 R tRNA-Val complement(1530354..1530429) Escherichia coli O104:H4 str. 2011C-3493 13702934 O3K_t25378 tRNA O3K_t25378 NC_018658.1 1530476 1530551 R tRNA-Val complement(1530476..1530551) Escherichia coli O104:H4 str. 2011C-3493 13702935 O3K_t25380 tRNA O3K_t25380 NC_018658.1 1530596 1530671 R tRNA-Val complement(1530596..1530671) Escherichia coli O104:H4 str. 2011C-3493 13702936 O3K_t25382 tRNA O3K_t25382 NC_018658.1 1533371 1533446 D tRNA-Ala 1533371..1533446 Escherichia coli O104:H4 str. 2011C-3493 13702940 O3K_t25384 tRNA O3K_t25384 NC_018658.1 1533486 1533561 D tRNA-Ala 1533486..1533561 Escherichia coli O104:H4 str. 2011C-3493 13702941 O3K_t25386 tRNA O3K_t25386 NC_018658.1 1604637 1604711 R tRNA-Arg complement(1604637..1604711) Escherichia coli O104:H4 str. 2011C-3493 13703012 O3K_t25388 tRNA O3K_t25388 NC_018658.1 1769497 1769573 R tRNA-Pro complement(1769497..1769573) Escherichia coli O104:H4 str. 2011C-3493 13703159 O3K_t25390 tRNA O3K_t25390 NC_018658.1 2009796 2009871 R tRNA-Asn complement(2009796..2009871) Escherichia coli O104:H4 str. 2011C-3493 13699448 O3K_t25392 tRNA O3K_t25392 NC_018658.1 2012205 2012280 R tRNA-Asn complement(2012205..2012280) Escherichia coli O104:H4 str. 2011C-3493 13699451 O3K_t25394 tRNA O3K_t25394 NC_018658.1 2014029 2014104 D tRNA-Asn 2014029..2014104 Escherichia coli O104:H4 str. 2011C-3493 13699453 O3K_t25396 tRNA O3K_t25396 NC_018658.1 2053920 2053995 R tRNA-Asn complement(2053920..2053995) Escherichia coli O104:H4 str. 2011C-3493 13699472 O3K_t25398 tRNA O3K_t25398 NC_018658.1 2054987 2055076 D tRNA-Ser 2054987..2055076 Escherichia coli O104:H4 str. 2011C-3493 13699474 O3K_t25400 tRNA O3K_t25400 NC_018658.1 2108755 2108830 D tRNA-Gly 2108755..2108830 Escherichia coli O104:H4 str. 2011C-3493 13699540 O3K_t25402 tRNA O3K_t25402 NC_018658.1 2108885 2108958 D tRNA-Cys 2108885..2108958 Escherichia coli O104:H4 str. 2011C-3493 13699541 O3K_t25404 tRNA O3K_t25404 NC_018658.1 2108971 2109057 D tRNA-Leu 2108971..2109057 Escherichia coli O104:H4 str. 2011C-3493 13699542 O3K_t25406 tRNA O3K_t25406 NC_018658.1 2167108 2167183 D tRNA-Met 2167108..2167183 Escherichia coli O104:H4 str. 2011C-3493 13699610 O3K_t25408 tRNA O3K_t25408 NC_018658.1 2167193 2167269 D tRNA-Arg 2167193..2167269 Escherichia coli O104:H4 str. 2011C-3493 13699611 O3K_t25410 tRNA O3K_t25410 NC_018658.1 2167283 2167359 D tRNA-Arg 2167283..2167359 Escherichia coli O104:H4 str. 2011C-3493 13699612 O3K_t25412 tRNA O3K_t25412 NC_018658.1 2442599 2442675 R tRNA-Val complement(2442599..2442675) Escherichia coli O104:H4 str. 2011C-3493 13701678 O3K_t25414 tRNA O3K_t25414 NC_018658.1 2442680 2442756 R tRNA-Val complement(2442680..2442756) Escherichia coli O104:H4 str. 2011C-3493 13701679 O3K_t25416 tRNA O3K_t25416 NC_018658.1 2925592 2925668 R tRNA-Arg complement(2925592..2925668) Escherichia coli O104:H4 str. 2011C-3493 13702568 O3K_t25418 tRNA O3K_t25418 NC_018658.1 2925682 2925758 R tRNA-Arg complement(2925682..2925758) Escherichia coli O104:H4 str. 2011C-3493 13702569 O3K_t25420 tRNA O3K_t25420 NC_018658.1 2925766 2925841 R tRNA-Met complement(2925766..2925841) Escherichia coli O104:H4 str. 2011C-3493 13702570 O3K_t25422 tRNA O3K_t25422 NC_018658.1 2965865 2965949 D tRNA-Tyr 2965865..2965949 Escherichia coli O104:H4 str. 2011C-3493 13700954 O3K_t25424 tRNA O3K_t25424 NC_018658.1 2965984 2966068 D tRNA-Tyr 2965984..2966068 Escherichia coli O104:H4 str. 2011C-3493 13700955 O3K_t25426 tRNA O3K_t25426 NC_018658.1 3140224 3140311 D tRNA-Ser 3140224..3140311 Escherichia coli O104:H4 str. 2011C-3493 13701133 O3K_t25428 tRNA O3K_t25428 NC_018658.1 3177234 3177304 D tRNA-OTHER 3177234..3177304 Escherichia coli O104:H4 str. 2011C-3493 13701174 O3K_t25430 tRNA O3K_t25430 NC_018658.1 3293167 3293243 R tRNA-Arg complement(3293167..3293243) Escherichia coli O104:H4 str. 2011C-3493 13701279 O3K_t25432 tRNA O3K_t25432 NC_018658.1 3293257 3293333 R tRNA-Arg complement(3293257..3293333) Escherichia coli O104:H4 str. 2011C-3493 13701280 O3K_t25434 tRNA O3K_t25434 NC_018658.1 3293343 3293418 R tRNA-Met complement(3293343..3293418) Escherichia coli O104:H4 str. 2011C-3493 13701281 O3K_t25436 tRNA O3K_t25436 NC_018658.1 3352121 3352208 D tRNA-Ser 3352121..3352208 Escherichia coli O104:H4 str. 2011C-3493 13701352 O3K_t25438 tRNA O3K_t25438 NC_018658.1 3459379 3459466 D tRNA-Ser 3459379..3459466 Escherichia coli O104:H4 str. 2011C-3493 13701442 O3K_t25440 tRNA O3K_t25440 NC_018658.1 3650074 3650149 R tRNA-Lys complement(3650074..3650149) Escherichia coli O104:H4 str. 2011C-3493 13701884 O3K_t25442 tRNA O3K_t25442 NC_018658.1 3650183 3650258 R tRNA-Lys complement(3650183..3650258) Escherichia coli O104:H4 str. 2011C-3493 13701885 O3K_t25444 tRNA O3K_t25444 NC_018658.1 3650405 3650480 R tRNA-Lys complement(3650405..3650480) Escherichia coli O104:H4 str. 2011C-3493 13701886 O3K_t25446 tRNA O3K_t25446 NC_018658.1 3650484 3650559 R tRNA-Val complement(3650484..3650559) Escherichia coli O104:H4 str. 2011C-3493 13701887 O3K_t25448 tRNA O3K_t25448 NC_018658.1 3650709 3650784 R tRNA-Lys complement(3650709..3650784) Escherichia coli O104:H4 str. 2011C-3493 13701888 O3K_t25450 tRNA O3K_t25450 NC_018658.1 3650787 3650862 R tRNA-Val complement(3650787..3650862) Escherichia coli O104:H4 str. 2011C-3493 13701889 O3K_t25452 tRNA O3K_t25452 NC_018658.1 3650898 3650973 R tRNA-Lys complement(3650898..3650973) Escherichia coli O104:H4 str. 2011C-3493 13701890 O3K_t25454 tRNA O3K_t25454 NC_018658.1 3728281 3728357 D tRNA-Met 3728281..3728357 Escherichia coli O104:H4 str. 2011C-3493 13702042 O3K_t25456 tRNA O3K_t25456 NC_018658.1 3728366 3728450 D tRNA-Leu 3728366..3728450 Escherichia coli O104:H4 str. 2011C-3493 13702043 O3K_t25458 tRNA O3K_t25458 NC_018658.1 3728474 3728548 D tRNA-Gln 3728474..3728548 Escherichia coli O104:H4 str. 2011C-3493 13702044 O3K_t25460 tRNA O3K_t25460 NC_018658.1 3728583 3728657 D tRNA-Gln 3728583..3728657 Escherichia coli O104:H4 str. 2011C-3493 13702045 O3K_t25462 tRNA O3K_t25462 NC_018658.1 3728673 3728749 D tRNA-Met 3728673..3728749 Escherichia coli O104:H4 str. 2011C-3493 13702046 O3K_t25464 tRNA O3K_t25464 NC_018658.1 3728798 3728872 D tRNA-Gln 3728798..3728872 Escherichia coli O104:H4 str. 2011C-3493 13702047 O3K_t25466 tRNA O3K_t25466 NC_018658.1 3728910 3728984 D tRNA-Gln 3728910..3728984 Escherichia coli O104:H4 str. 2011C-3493 13702048 O3K_t25468 tRNA O3K_t25468 NC_018658.1 3851761 3851837 R tRNA-Arg complement(3851761..3851837) Escherichia coli O104:H4 str. 2011C-3493 13702235 O3K_t25470 tRNA O3K_t25470 NC_018658.1 4069354 4069434 R tRNA-OTHER complement(4069354..4069434) Escherichia coli O104:H4 str. 2011C-3493 13702641 O3K_t25472 tRNA O3K_t25472 NC_018658.1 4156919 4156994 R tRNA-Thr complement(4156919..4156994) Escherichia coli O104:H4 str. 2011C-3493 13703290 O3K_t25474 tRNA O3K_t25474 NC_018658.1 4212684 4212760 R tRNA-Asp complement(4212684..4212760) Escherichia coli O104:H4 str. 2011C-3493 13703341 O3K_t25476 tRNA O3K_t25476 NC_018658.1 4220907 4220983 R tRNA-Asp complement(4220907..4220983) Escherichia coli O104:H4 str. 2011C-3493 13703351 O3K_t25478 tRNA O3K_t25478 NC_018658.1 4224475 4224550 R tRNA-Ala complement(4224475..4224550) Escherichia coli O104:H4 str. 2011C-3493 13703354 O3K_t25480 tRNA O3K_t25480 NC_018658.1 4224593 4224669 R tRNA-Ile complement(4224593..4224669) Escherichia coli O104:H4 str. 2011C-3493 13703355 O3K_t25482 tRNA O3K_t25482 NC_018658.1 4484464 4484550 D tRNA-Leu 4484464..4484550 Escherichia coli O104:H4 str. 2011C-3493 13703586 O3K_t25484 tRNA O3K_t25484 NC_018658.1 4484579 4484665 D tRNA-Leu 4484579..4484665 Escherichia coli O104:H4 str. 2011C-3493 13703587 O3K_t25486 tRNA O3K_t25486 NC_018658.1 4484700 4484786 D tRNA-Leu 4484700..4484786 Escherichia coli O104:H4 str. 2011C-3493 13703588 O3K_t25488 tRNA O3K_t25488 NC_018658.1 4599857 4599941 R tRNA-Leu complement(4599857..4599941) Escherichia coli O104:H4 str. 2011C-3493 13703701 O3K_t25490 tRNA O3K_t25490 NC_018658.1 4705900 4705975 R tRNA-Gly complement(4705900..4705975) Escherichia coli O104:H4 str. 2011C-3493 13699826 O3K_t25492 tRNA O3K_t25492 NC_018658.1 4735703 4735778 D tRNA-Phe 4735703..4735778 Escherichia coli O104:H4 str. 2011C-3493 13699857 O3K_t25494 tRNA O3K_t25494 NC_018658.1 4931992 4932067 R tRNA-Ala complement(4931992..4932067) Escherichia coli O104:H4 str. 2011C-3493 13700024 O3K_t25496 tRNA O3K_t25496 NC_018658.1 4932110 4932186 R tRNA-Ile complement(4932110..4932186) Escherichia coli O104:H4 str. 2011C-3493 13700025 O3K_t25498 tRNA O3K_t25498 NC_018658.1 4966093 4966168 R tRNA-Thr complement(4966093..4966168) Escherichia coli O104:H4 str. 2011C-3493 13700055 O3K_t25500 tRNA O3K_t25500 NC_018658.1 4966175 4966249 R tRNA-Gly complement(4966175..4966249) Escherichia coli O104:H4 str. 2011C-3493 13700056 O3K_t25502 tRNA O3K_t25502 NC_018658.1 4966366 4966450 R tRNA-Tyr complement(4966366..4966450) Escherichia coli O104:H4 str. 2011C-3493 13700057 O3K_t25504 tRNA O3K_t25504 NC_018658.1 4966459 4966534 R tRNA-Thr complement(4966459..4966534) Escherichia coli O104:H4 str. 2011C-3493 13700058 O3K_t25506 tRNA O3K_t25506 NC_018658.1 4973466 4973541 R tRNA-Ala complement(4973466..4973541) Escherichia coli O104:H4 str. 2011C-3493 13700064 O3K_t25508 tRNA O3K_t25508 NC_018658.1 4973584 4973660 R tRNA-Ile complement(4973584..4973660) Escherichia coli O104:H4 str. 2011C-3493 13700065 O3K_t25510 tRNA O3K_t25510 NC_018658.1 5110676 5110751 R tRNA-Ala complement(5110676..5110751) Escherichia coli O104:H4 str. 2011C-3493 13700193 O3K_t25512 tRNA O3K_t25512 NC_018658.1 5110794 5110870 R tRNA-Ile complement(5110794..5110870) Escherichia coli O104:H4 str. 2011C-3493 13700194 O3K_t25514 tRNA O3K_t25514 NC_018658.1 5168822 5168898 R tRNA-Pro complement(5168822..5168898) Escherichia coli O104:H4 str. 2011C-3493 13700250 O3K_t25516 tRNA O3K_t25516 NC_018658.1 5168941 5169027 R tRNA-Leu complement(5168941..5169027) Escherichia coli O104:H4 str. 2011C-3493 13700251 O3K_t25518 tRNA O3K_t25518 NC_018658.1 5169048 5169123 R tRNA-His complement(5169048..5169123) Escherichia coli O104:H4 str. 2011C-3493 13700252 O3K_t25520 tRNA O3K_t25520 NC_018658.1 5169182 5169258 R tRNA-Arg complement(5169182..5169258) Escherichia coli O104:H4 str. 2011C-3493 13700253 O3K_t25522 tRNA O3K_t25522 NC_018658.1 5204602 5204677 R tRNA-Trp complement(5204602..5204677) Escherichia coli O104:H4 str. 2011C-3493 13700286 O3K_t25524 tRNA O3K_t25524 NC_018658.1 5204686 5204762 R tRNA-Asp complement(5204686..5204762) Escherichia coli O104:H4 str. 2011C-3493 13700287 O3K_t25526 tRNA O3K_t25526 NC_018658.1 5208114 5208189 R tRNA-Ala complement(5208114..5208189) Escherichia coli O104:H4 str. 2011C-3493 13700290 O3K_t25528 tRNA O3K_t25528 NC_018658.1 5208232 5208308 R tRNA-Ile complement(5208232..5208308) Escherichia coli O104:H4 str. 2011C-3493 13700291 O3K_r25546 rRNA O3K_r25546 NC_018658.1 524780 526334 D 16S ribosomal RNA 524780..526334 Escherichia coli O104:H4 str. 2011C-3493 13699186 O3K_r25560 rRNA O3K_r25560 NC_018658.1 526769 529675 D 23S ribosomal RNA 526769..529675 Escherichia coli O104:H4 str. 2011C-3493 13699189 O3K_r25530 rRNA O3K_r25530 NC_018658.1 529769 529884 D 5S ribosomal RNA 529769..529884 Escherichia coli O104:H4 str. 2011C-3493 13699190 O3K_r25532 rRNA O3K_r25532 NC_018658.1 530014 530129 D 5S ribosomal RNA 530014..530129 Escherichia coli O104:H4 str. 2011C-3493 13699192 O3K_r25548 rRNA O3K_r25548 NC_018658.1 1328227 1329780 D 16S ribosomal RNA 1328227..1329780 Escherichia coli O104:H4 str. 2011C-3493 13702744 O3K_r25562 rRNA O3K_r25562 NC_018658.1 1330209 1333114 D 23S ribosomal RNA 1330209..1333114 Escherichia coli O104:H4 str. 2011C-3493 13702746 O3K_r25534 rRNA O3K_r25534 NC_018658.1 1333208 1333323 D 5S ribosomal RNA 1333208..1333323 Escherichia coli O104:H4 str. 2011C-3493 13702747 O3K_r25536 rRNA O3K_r25536 NC_018658.1 4221177 4221292 R 5S ribosomal RNA complement(4221177..4221292) Escherichia coli O104:H4 str. 2011C-3493 13703352 O3K_r25564 rRNA O3K_r25564 NC_018658.1 4221386 4224291 R 23S ribosomal RNA complement(4221386..4224291) Escherichia coli O104:H4 str. 2011C-3493 13703353 O3K_r25550 rRNA O3K_r25550 NC_018658.1 4224726 4226280 R 16S ribosomal RNA complement(4224726..4226280) Escherichia coli O104:H4 str. 2011C-3493 13703356 O3K_r25538 rRNA O3K_r25538 NC_018658.1 4928695 4928810 R 5S ribosomal RNA complement(4928695..4928810) Escherichia coli O104:H4 str. 2011C-3493 13700022 O3K_r25566 rRNA O3K_r25566 NC_018658.1 4928903 4931808 R 23S ribosomal RNA complement(4928903..4931808) Escherichia coli O104:H4 str. 2011C-3493 13700023 O3K_r25552 rRNA O3K_r25552 NC_018658.1 4932243 4933796 R 16S ribosomal RNA complement(4932243..4933796) Escherichia coli O104:H4 str. 2011C-3493 13700026 O3K_r25540 rRNA O3K_r25540 NC_018658.1 4970168 4970283 R 5S ribosomal RNA complement(4970168..4970283) Escherichia coli O104:H4 str. 2011C-3493 13700062 O3K_r25568 rRNA O3K_r25568 NC_018658.1 4970377 4973282 R 23S ribosomal RNA complement(4970377..4973282) Escherichia coli O104:H4 str. 2011C-3493 13700063 O3K_r25554 rRNA O3K_r25554 NC_018658.1 4973717 4975270 R 16S ribosomal RNA complement(4973717..4975270) Escherichia coli O104:H4 str. 2011C-3493 13700066 O3K_r25542 rRNA O3K_r25542 NC_018658.1 5107378 5107493 R 5S ribosomal RNA complement(5107378..5107493) Escherichia coli O104:H4 str. 2011C-3493 13700191 O3K_r25570 rRNA O3K_r25570 NC_018658.1 5107587 5110492 R 23S ribosomal RNA complement(5107587..5110492) Escherichia coli O104:H4 str. 2011C-3493 13700192 O3K_r25556 rRNA O3K_r25556 NC_018658.1 5110927 5112481 R 16S ribosomal RNA complement(5110927..5112481) Escherichia coli O104:H4 str. 2011C-3493 13700195 O3K_r25544 rRNA O3K_r25544 NC_018658.1 5204817 5204932 R 5S ribosomal RNA complement(5204817..5204932) Escherichia coli O104:H4 str. 2011C-3493 13700288 O3K_r25572 rRNA O3K_r25572 NC_018658.1 5205025 5207930 R 23S ribosomal RNA complement(5205025..5207930) Escherichia coli O104:H4 str. 2011C-3493 13700289 O3K_r25558 rRNA O3K_r25558 NC_018658.1 5208365 5209919 R 16S ribosomal RNA complement(5208365..5209919) Escherichia coli O104:H4 str. 2011C-3493 13700292