-- dump date 20140619_085252 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 1134782000001 SEQ_END SEQ_END NC_018650.1 5253138 5253138 DR NC_018650.1; contig end 5253138..5253138 Escherichia coli O104:H4 str. 2009EL-2050 1134782000002 SEQ_END SEQ_END NC_018651.1 109274 109274 DR NC_018651.1; contig end 109274..109274 Escherichia coli O104:H4 str. 2009EL-2050 1134782000003 SEQ_END SEQ_END NC_018652.1 1549 1549 DR NC_018652.1; contig end 1549..1549 Escherichia coli O104:H4 str. 2009EL-2050 1134782000004 SEQ_END SEQ_END NC_018654.1 74213 74213 DR NC_018654.1; contig end 74213..74213 Escherichia coli O104:H4 str. 2009EL-2050 YP_006767686.1 CDS dnaA NC_018650.1 33 1436 D COG0593 ATPase involved in DNA replication initiation; chromosomal replication initiation protein 33..1436 Escherichia coli O104:H4 str. 2009EL-2050 13692995 YP_006767687.1 CDS O3M_00010 NC_018650.1 1441 2541 D COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase III subunit beta 1441..2541 Escherichia coli O104:H4 str. 2009EL-2050 13689911 YP_006767688.1 CDS recF NC_018650.1 2541 3614 D COG1195 Recombinational DNA repair ATPase (RecF pathway); recombination protein F 2541..3614 Escherichia coli O104:H4 str. 2009EL-2050 13689912 YP_006767689.1 CDS gyrB NC_018650.1 3643 6057 D COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA gyrase subunit B 3643..6057 Escherichia coli O104:H4 str. 2009EL-2050 13689913 YP_006767690.1 CDS O3M_00025 NC_018650.1 6077 6277 D hypothetical protein 6077..6277 Escherichia coli O104:H4 str. 2009EL-2050 13689914 YP_006767691.1 CDS O3M_00030 NC_018650.1 6297 6695 D COG3753 Uncharacterized protein conserved in bacteria; hypothetical protein 6297..6695 Escherichia coli O104:H4 str. 2009EL-2050 13689915 YP_006767692.1 CDS O3M_00035 NC_018650.1 6810 7622 D COG0561 Predicted hydrolases of the HAD superfamily; sugar phosphate phosphatase 6810..7622 Escherichia coli O104:H4 str. 2009EL-2050 13689916 YP_006767693.1 CDS O3M_00040 NC_018650.1 7668 8324 R hypothetical protein complement(7668..8324) Escherichia coli O104:H4 str. 2009EL-2050 13689917 YP_006767694.1 CDS O3M_00045 NC_018650.1 8602 9291 D COG2186 Transcriptional regulators; DNA-binding transcriptional regulator 8602..9291 Escherichia coli O104:H4 str. 2009EL-2050 13689918 YP_006767695.1 CDS O3M_00050 NC_018650.1 9288 10166 D COG3734 2-keto-3-deoxy-galactonokinase; 2-oxo-3-deoxygalactonate kinase 9288..10166 Escherichia coli O104:H4 str. 2009EL-2050 13689919 YP_006767696.1 CDS O3M_00055 NC_018650.1 10150 10767 D COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 10150..10767 Escherichia coli O104:H4 str. 2009EL-2050 13689920 YP_006767697.1 CDS O3M_00060 NC_018650.1 10764 11912 D COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; galactonate dehydratase 10764..11912 Escherichia coli O104:H4 str. 2009EL-2050 13689921 YP_006767698.1 CDS O3M_00065 NC_018650.1 12032 13324 D COG0477 Permeases of the major facilitator superfamily; D-galactonate transporter 12032..13324 Escherichia coli O104:H4 str. 2009EL-2050 13689922 YP_006767699.1 CDS O3M_00070 NC_018650.1 13321 14385 R COG0644 Dehydrogenases (flavoproteins); oxidoreductase complement(13321..14385) Escherichia coli O104:H4 str. 2009EL-2050 13689923 YP_006767700.1 CDS O3M_00075 NC_018650.1 14486 15700 D COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; hypothetical protein 14486..15700 Escherichia coli O104:H4 str. 2009EL-2050 13689924 YP_006767701.1 CDS O3M_00080 NC_018650.1 15702 16034 R COG5645 Predicted periplasmic lipoprotein; hypothetical protein complement(15702..16034) Escherichia coli O104:H4 str. 2009EL-2050 13689925 YP_006767702.1 CDS O3M_00085 NC_018650.1 16340 16753 D COG0071 Molecular chaperone (small heat shock protein); heat shock protein IbpA 16340..16753 Escherichia coli O104:H4 str. 2009EL-2050 13689926 YP_006767703.1 CDS O3M_00090 NC_018650.1 16865 17293 D COG0071 Molecular chaperone (small heat shock protein); heat shock chaperone IbpB 16865..17293 Escherichia coli O104:H4 str. 2009EL-2050 13689927 YP_006767704.1 CDS O3M_00095 NC_018650.1 17490 19151 D COG2985 Predicted permease; transporter 17490..19151 Escherichia coli O104:H4 str. 2009EL-2050 13689928 YP_006767705.1 CDS O3M_00100 NC_018650.1 19148 19864 R COG2188 Transcriptional regulators; DNA-binding transcriptional regulator complement(19148..19864) Escherichia coli O104:H4 str. 2009EL-2050 13689929 YP_006767706.1 CDS O3M_00105 NC_018650.1 20160 21776 D COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system arbutin-like transporter subunit IIC 20160..21776 Escherichia coli O104:H4 str. 2009EL-2050 13689930 YP_006767707.1 CDS O3M_00110 NC_018650.1 21776 22414 D COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; 6-phospho-beta-glucosidase 21776..22414 Escherichia coli O104:H4 str. 2009EL-2050 13689931 YP_006767708.1 CDS O3M_00115 NC_018650.1 22414 22590 D COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; glycoside hydrolase 22414..22590 Escherichia coli O104:H4 str. 2009EL-2050 13689932 YP_006767709.1 CDS O3M_00120 NC_018650.1 22587 23147 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator complement(22587..23147) Escherichia coli O104:H4 str. 2009EL-2050 13689933 YP_006767710.1 CDS O3M_00125 NC_018650.1 23216 23491 D COG3677 Transposase and inactivated derivatives; InsA 23216..23491 Escherichia coli O104:H4 str. 2009EL-2050 13689934 YP_006767711.1 CDS O3M_00130 NC_018650.1 23410 23913 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 23410..23913 Escherichia coli O104:H4 str. 2009EL-2050 13689935 YP_006767712.1 CDS O3M_00135 NC_018650.1 23928 24257 R DNA-binding transcriptional regulator complement(23928..24257) Escherichia coli O104:H4 str. 2009EL-2050 13689936 YP_006767713.1 CDS O3M_00140 NC_018650.1 24424 26139 D COG4146 Predicted symporter; transporter 24424..26139 Escherichia coli O104:H4 str. 2009EL-2050 13689937 YP_006767714.1 CDS O3M_00145 NC_018650.1 26136 27629 D COG3119 Arylsulfatase A and related enzymes; sulfatase/phosphatase 26136..27629 Escherichia coli O104:H4 str. 2009EL-2050 13689938 YP_006767715.1 CDS O3M_00150 NC_018650.1 27676 28125 R inner membrane protein complement(27676..28125) Escherichia coli O104:H4 str. 2009EL-2050 13689939 YP_006767716.1 CDS O3M_00155 NC_018650.1 28234 28581 D COG2149 Predicted membrane protein; inner membrane protein YidH 28234..28581 Escherichia coli O104:H4 str. 2009EL-2050 13689940 YP_006767717.1 CDS O3M_00160 NC_018650.1 28571 28933 D hypothetical protein 28571..28933 Escherichia coli O104:H4 str. 2009EL-2050 13689941 YP_006767718.1 CDS O3M_00165 NC_018650.1 28930 29427 D COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); transcriptional regulator 28930..29427 Escherichia coli O104:H4 str. 2009EL-2050 13689942 YP_006767719.1 CDS emrD NC_018650.1 29435 30619 R COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein D complement(29435..30619) Escherichia coli O104:H4 str. 2009EL-2050 13689943 YP_006767720.1 CDS O3M_00175 NC_018650.1 31038 31127 R toxic peptide TisB complement(31038..31127) Escherichia coli O104:H4 str. 2009EL-2050 13689944 YP_006767721.1 CDS O3M_00180 NC_018650.1 31415 31897 R hypothetical protein complement(31415..31897) Escherichia coli O104:H4 str. 2009EL-2050 13689945 YP_006767722.1 CDS O3M_00185 NC_018650.1 31896 33584 D COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase catalytic subunit 31896..33584 Escherichia coli O104:H4 str. 2009EL-2050 13689946 YP_006767723.1 CDS O3M_00190 NC_018650.1 33588 33878 D COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase 1 regulatory subunit 33588..33878 Escherichia coli O104:H4 str. 2009EL-2050 13689947 YP_006767724.1 CDS O3M_00195 NC_018650.1 33953 34543 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator UhpA 33953..34543 Escherichia coli O104:H4 str. 2009EL-2050 13689948 YP_006767725.1 CDS O3M_00200 NC_018650.1 34543 36045 D COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific; sensory histidine kinase UhpB 34543..36045 Escherichia coli O104:H4 str. 2009EL-2050 13689949 YP_006767726.1 CDS O3M_00205 NC_018650.1 36055 37374 D COG2271 Sugar phosphate permease; regulatory protein UhpC 36055..37374 Escherichia coli O104:H4 str. 2009EL-2050 13689950 YP_006767727.1 CDS uhpT NC_018650.1 37512 38903 D COG2271 Sugar phosphate permease; sugar phosphate antiporter 37512..38903 Escherichia coli O104:H4 str. 2009EL-2050 13689951 YP_006767728.1 CDS O3M_00215 NC_018650.1 38948 40714 R COG1001 Adenine deaminase; cryptic adenine deaminase complement(38948..40714) Escherichia coli O104:H4 str. 2009EL-2050 13689952 YP_006767729.1 CDS O3M_00220 NC_018650.1 40889 42223 D COG2252 Permeases; hypothetical protein 40889..42223 Escherichia coli O104:H4 str. 2009EL-2050 13689953 YP_006767730.1 CDS O3M_00225 NC_018650.1 42276 42728 D COG0442 Prolyl-tRNA synthetase; hypothetical protein 42276..42728 Escherichia coli O104:H4 str. 2009EL-2050 13689954 YP_006767731.1 CDS nepI NC_018650.1 42939 44123 D COG2814 Arabinose efflux permease; ribonucleoside transporter 42939..44123 Escherichia coli O104:H4 str. 2009EL-2050 13689955 YP_006767732.1 CDS O3M_00235 NC_018650.1 44164 44457 R hypothetical protein complement(44164..44457) Escherichia coli O104:H4 str. 2009EL-2050 13689956 YP_006767733.1 CDS O3M_00240 NC_018650.1 44462 44581 R hypothetical protein complement(44462..44581) Escherichia coli O104:H4 str. 2009EL-2050 13689957 YP_006767734.1 CDS O3M_00245 NC_018650.1 44679 45497 D COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; hypothetical protein 44679..45497 Escherichia coli O104:H4 str. 2009EL-2050 13689958 YP_006767735.1 CDS O3M_00250 NC_018650.1 45501 46424 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein complement(45501..46424) Escherichia coli O104:H4 str. 2009EL-2050 13689959 YP_006767736.1 CDS O3M_00255 NC_018650.1 46535 47719 R COG0477 Permeases of the major facilitator superfamily; sugar efflux system complement(46535..47719) Escherichia coli O104:H4 str. 2009EL-2050 13689960 YP_006767737.1 CDS O3M_00260 NC_018650.1 48101 48250 R COG3943 Virulence protein; hypothetical protein complement(48101..48250) Escherichia coli O104:H4 str. 2009EL-2050 13689961 YP_006767738.1 CDS O3M_00265 NC_018650.1 48512 49357 R hypothetical protein complement(48512..49357) Escherichia coli O104:H4 str. 2009EL-2050 13689962 YP_006767739.1 CDS O3M_00270 NC_018650.1 49442 49639 R hypothetical protein complement(49442..49639) Escherichia coli O104:H4 str. 2009EL-2050 13689963 YP_006767740.1 CDS O3M_00275 NC_018650.1 49659 50147 R hypothetical protein complement(49659..50147) Escherichia coli O104:H4 str. 2009EL-2050 13689964 YP_006767741.1 CDS O3M_00280 NC_018650.1 50144 50521 R hypothetical protein complement(50144..50521) Escherichia coli O104:H4 str. 2009EL-2050 13689965 YP_006767742.1 CDS O3M_00285 NC_018650.1 50568 50945 R hypothetical protein complement(50568..50945) Escherichia coli O104:H4 str. 2009EL-2050 13689966 YP_006767743.1 CDS O3M_00290 NC_018650.1 50995 51108 R hypothetical protein complement(50995..51108) Escherichia coli O104:H4 str. 2009EL-2050 13689967 YP_006767744.1 CDS O3M_00295 NC_018650.1 51108 51329 R hypothetical protein complement(51108..51329) Escherichia coli O104:H4 str. 2009EL-2050 13689968 YP_006767745.1 CDS O3M_00300 NC_018650.1 51392 51868 R COG2003 DNA repair proteins; DNA repair protein complement(51392..51868) Escherichia coli O104:H4 str. 2009EL-2050 13689969 YP_006767746.1 CDS O3M_00305 NC_018650.1 51884 52357 R hypothetical protein complement(51884..52357) Escherichia coli O104:H4 str. 2009EL-2050 13689970 YP_006767747.1 CDS O3M_00310 NC_018650.1 52523 52696 R antirestriction protein complement(52523..52696) Escherichia coli O104:H4 str. 2009EL-2050 13689971 YP_006767748.1 CDS O3M_00315 NC_018650.1 52696 53514 R hypothetical protein complement(52696..53514) Escherichia coli O104:H4 str. 2009EL-2050 13689972 YP_006767749.1 CDS O3M_00320 NC_018650.1 53669 53827 R hypothetical protein complement(53669..53827) Escherichia coli O104:H4 str. 2009EL-2050 13689973 YP_006767750.1 CDS O3M_00325 NC_018650.1 53898 56744 R COG5295 Autotransporter adhesin; antigen 43 precursor (AG43, Fluffing protein) complement(53898..56744) Escherichia coli O104:H4 str. 2009EL-2050 13689974 YP_006767751.1 CDS O3M_00330 NC_018650.1 57117 57989 R COG3596 Predicted GTPase; hypothetical protein complement(57117..57989) Escherichia coli O104:H4 str. 2009EL-2050 13689975 YP_006767752.1 CDS O3M_00335 NC_018650.1 58088 58960 R hypothetical protein complement(58088..58960) Escherichia coli O104:H4 str. 2009EL-2050 13689976 YP_006767753.1 CDS O3M_00340 NC_018650.1 60603 60815 R COG1484 DNA replication protein; IstB ATP binding domain-containing protein complement(60603..60815) Escherichia coli O104:H4 str. 2009EL-2050 13689977 YP_006767754.1 CDS O3M_00345 NC_018650.1 61448 61645 D hypothetical protein 61448..61645 Escherichia coli O104:H4 str. 2009EL-2050 13689978 YP_006767755.1 CDS O3M_00350 NC_018650.1 61548 62156 R hypothetical protein complement(61548..62156) Escherichia coli O104:H4 str. 2009EL-2050 13689979 YP_006767756.1 CDS O3M_00355 NC_018650.1 62245 62451 R COG3311 Predicted transcriptional regulator; Prophage CP4-57 regulatory protein complement(62245..62451) Escherichia coli O104:H4 str. 2009EL-2050 13689980 YP_006767757.1 CDS O3M_00360 NC_018650.1 63230 63370 D hemolysin expression modulating protein 63230..63370 Escherichia coli O104:H4 str. 2009EL-2050 13689981 YP_006767758.1 CDS O3M_00365 NC_018650.1 64114 64683 D hypothetical protein 64114..64683 Escherichia coli O104:H4 str. 2009EL-2050 13689982 YP_006767759.1 CDS O3M_00370 NC_018650.1 64849 65232 D COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 64849..65232 Escherichia coli O104:H4 str. 2009EL-2050 13689983 YP_006767760.1 CDS O3M_00375 NC_018650.1 65229 65438 D hypothetical protein 65229..65438 Escherichia coli O104:H4 str. 2009EL-2050 13689984 YP_006767761.1 CDS O3M_00380 NC_018650.1 65985 66686 D COG2801 Transposase and inactivated derivatives; transposase 65985..66686 Escherichia coli O104:H4 str. 2009EL-2050 13689985 YP_006767762.1 CDS O3M_00385 NC_018650.1 66671 67531 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; transporter permease 66671..67531 Escherichia coli O104:H4 str. 2009EL-2050 13689986 YP_006767763.1 CDS O3M_00390 NC_018650.1 67563 68837 R COG0477 Permeases of the major facilitator superfamily; tetracycline efflux protein complement(67563..68837) Escherichia coli O104:H4 str. 2009EL-2050 13689987 YP_006767764.1 CDS O3M_00395 NC_018650.1 68841 69518 D COG1309 Transcriptional regulator; tetracycline repressor protein 68841..69518 Escherichia coli O104:H4 str. 2009EL-2050 13689988 YP_006767765.1 CDS O3M_00400 NC_018650.1 69550 69792 R transposase complement(69550..69792) Escherichia coli O104:H4 str. 2009EL-2050 13689989 YP_006767766.1 CDS O3M_00405 NC_018650.1 69715 69879 D hypothetical protein 69715..69879 Escherichia coli O104:H4 str. 2009EL-2050 13689990 YP_006767767.1 CDS O3M_00410 NC_018650.1 70088 70204 D hypothetical protein 70088..70204 Escherichia coli O104:H4 str. 2009EL-2050 13689991 YP_006767768.1 CDS O3M_00415 NC_018650.1 70426 70758 R hypothetical protein complement(70426..70758) Escherichia coli O104:H4 str. 2009EL-2050 13689992 YP_006767769.1 CDS O3M_00420 NC_018650.1 70795 71229 R COG0789 Predicted transcriptional regulators; transcriptional regulator MerR complement(70795..71229) Escherichia coli O104:H4 str. 2009EL-2050 13689993 YP_006767770.1 CDS O3M_00425 NC_018650.1 71301 71651 D mercuric transport protein 71301..71651 Escherichia coli O104:H4 str. 2009EL-2050 13689994 YP_006767771.1 CDS O3M_00430 NC_018650.1 71665 71940 D COG2608 Copper chaperone; mercury resistance operon protein MerP 71665..71940 Escherichia coli O104:H4 str. 2009EL-2050 13689995 YP_006767772.1 CDS O3M_00435 NC_018650.1 71976 72398 D mercury transport protein MerC 71976..72398 Escherichia coli O104:H4 str. 2009EL-2050 13689996 YP_006767773.1 CDS O3M_00440 NC_018650.1 72450 74144 D COG2608 Copper chaperone; mercuric reductase 72450..74144 Escherichia coli O104:H4 str. 2009EL-2050 13689997 YP_006767774.1 CDS O3M_00445 NC_018650.1 74162 74524 D COG0789 Predicted transcriptional regulators; transcriptional regulator MerD 74162..74524 Escherichia coli O104:H4 str. 2009EL-2050 13689998 YP_006767775.1 CDS O3M_00450 NC_018650.1 74521 74757 D mercury resistance protein 74521..74757 Escherichia coli O104:H4 str. 2009EL-2050 13689999 YP_006767776.1 CDS O3M_00455 NC_018650.1 74754 75461 D COG2200 FOG: EAL domain; hypothetical protein 74754..75461 Escherichia coli O104:H4 str. 2009EL-2050 13690000 YP_006767777.1 CDS O3M_00460 NC_018650.1 75500 76798 D COG2801 Transposase and inactivated derivatives; TniA protein 75500..76798 Escherichia coli O104:H4 str. 2009EL-2050 13690001 YP_006767778.1 CDS O3M_00465 NC_018650.1 76845 77549 D COG3316 Transposase and inactivated derivatives; transposase 76845..77549 Escherichia coli O104:H4 str. 2009EL-2050 13690002 YP_006767779.1 CDS O3M_00470 NC_018650.1 77610 78446 R COG3570 Streptomycin 6-kinase; streptomycin phosphotransferase complement(77610..78446) Escherichia coli O104:H4 str. 2009EL-2050 13690003 YP_006767780.1 CDS O3M_00475 NC_018650.1 78446 79249 R COG3231 Aminoglycoside phosphotransferase; hypothetical protein complement(78446..79249) Escherichia coli O104:H4 str. 2009EL-2050 13690004 YP_006767781.1 CDS O3M_00480 NC_018650.1 79310 80125 R COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase complement(79310..80125) Escherichia coli O104:H4 str. 2009EL-2050 13690005 YP_006767782.1 CDS O3M_00485 NC_018650.1 80433 81284 R replication protein C complement(80433..81284) Escherichia coli O104:H4 str. 2009EL-2050 13690006 YP_006767783.1 CDS O3M_00490 NC_018650.1 81271 81978 R COG3598 RecA-family ATPase; replication protein A complement(81271..81978) Escherichia coli O104:H4 str. 2009EL-2050 13690007 YP_006767784.1 CDS O3M_00495 NC_018650.1 82040 82744 R COG3316 Transposase and inactivated derivatives; transposase complement(82040..82744) Escherichia coli O104:H4 str. 2009EL-2050 13690008 YP_006767785.1 CDS O3M_00500 NC_018650.1 82791 83192 R COG1110 Reverse gyrase; hypothetical protein complement(82791..83192) Escherichia coli O104:H4 str. 2009EL-2050 13690009 YP_006767786.1 CDS O3M_00505 NC_018650.1 83342 84202 R COG2367 Beta-lactamase class A; beta-lactamase TEM complement(83342..84202) Escherichia coli O104:H4 str. 2009EL-2050 13690010 YP_006767787.1 CDS O3M_00510 NC_018650.1 84385 84627 R COG1961 Site-specific recombinases, DNA invertase Pin homologs; hypothetical protein complement(84385..84627) Escherichia coli O104:H4 str. 2009EL-2050 13690011 YP_006767788.1 CDS O3M_00515 NC_018650.1 84702 85406 D COG3316 Transposase and inactivated derivatives; transposase 84702..85406 Escherichia coli O104:H4 str. 2009EL-2050 13690012 YP_006767789.1 CDS O3M_00520 NC_018650.1 85603 85803 R modulator protein complement(85603..85803) Escherichia coli O104:H4 str. 2009EL-2050 13690013 YP_006767790.1 CDS O3M_00525 NC_018650.1 86018 86197 D transcriptional regulator 86018..86197 Escherichia coli O104:H4 str. 2009EL-2050 13690014 YP_006767791.1 CDS O3M_00530 NC_018650.1 86156 87169 R COG0582 Integrase; integrase/recombinase complement(86156..87169) Escherichia coli O104:H4 str. 2009EL-2050 13690015 YP_006767792.1 CDS O3M_00535 NC_018650.1 87327 87800 D COG0262 Dihydrofolate reductase; dihydrofolate reductase 87327..87800 Escherichia coli O104:H4 str. 2009EL-2050 13690016 YP_006767793.1 CDS O3M_00540 NC_018650.1 88030 88377 D COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein 88030..88377 Escherichia coli O104:H4 str. 2009EL-2050 13690017 YP_006767794.1 CDS O3M_00545 NC_018650.1 88371 89150 D COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase 88371..89150 Escherichia coli O104:H4 str. 2009EL-2050 13690018 YP_006767795.1 CDS O3M_00550 NC_018650.1 89184 89888 R COG3316 Transposase and inactivated derivatives; transposase complement(89184..89888) Escherichia coli O104:H4 str. 2009EL-2050 13690019 YP_006767796.1 CDS O3M_00555 NC_018650.1 89947 90501 D COG1961 Site-specific recombinases, DNA invertase Pin homologs; Tn21 resolvase 89947..90501 Escherichia coli O104:H4 str. 2009EL-2050 13690020 YP_006767797.1 CDS O3M_00560 NC_018650.1 90504 93470 D COG4644 Transposase and inactivated derivatives, TnpA family; transposase TnpA, Tn21 90504..93470 Escherichia coli O104:H4 str. 2009EL-2050 13690021 YP_006767798.1 CDS O3M_00565 NC_018650.1 93537 93626 D acetyltransferase 93537..93626 Escherichia coli O104:H4 str. 2009EL-2050 13690022 YP_006767799.1 CDS O3M_00570 NC_018650.1 93660 93935 D COG3677 Transposase and inactivated derivatives; InsA 93660..93935 Escherichia coli O104:H4 str. 2009EL-2050 13690023 YP_006767800.1 CDS O3M_00575 NC_018650.1 93854 94357 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 93854..94357 Escherichia coli O104:H4 str. 2009EL-2050 13690024 YP_006767801.1 CDS O3M_00580 NC_018650.1 94476 95660 R COG0582 Integrase; hypothetical protein complement(94476..95660) Escherichia coli O104:H4 str. 2009EL-2050 13690025 YP_006767802.1 CDS O3M_00585 NC_018650.1 96347 97729 D COG2211 Na+/melibiose symporter and related transporters; transporter 96347..97729 Escherichia coli O104:H4 str. 2009EL-2050 13690027 YP_006767803.1 CDS O3M_00590 NC_018650.1 97739 100057 D COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; alpha-glucosidase 97739..100057 Escherichia coli O104:H4 str. 2009EL-2050 13690028 YP_006767804.1 CDS O3M_00595 NC_018650.1 100110 101819 R hypothetical protein complement(100110..101819) Escherichia coli O104:H4 str. 2009EL-2050 13690029 YP_006767805.1 CDS O3M_00600 NC_018650.1 101940 103331 R COG2233 Xanthine/uracil permeases; purine permease yicE complement(101940..103331) Escherichia coli O104:H4 str. 2009EL-2050 13690030 YP_006767806.1 CDS O3M_00605 NC_018650.1 103611 104816 D COG0786 Na+/glutamate symporter; sodium/glutamate symporter 103611..104816 Escherichia coli O104:H4 str. 2009EL-2050 13690031 YP_006767807.1 CDS O3M_00610 NC_018650.1 104982 107063 R COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG complement(104982..107063) Escherichia coli O104:H4 str. 2009EL-2050 13690032 YP_006767808.1 CDS O3M_00615 NC_018650.1 107069 107758 R COG0566 rRNA methylases; tRNA guanosine-2'-O-methyltransferase complement(107069..107758) Escherichia coli O104:H4 str. 2009EL-2050 13690033 YP_006767809.1 CDS O3M_00620 NC_018650.1 107765 109873 R COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase complement(107765..109873) Escherichia coli O104:H4 str. 2009EL-2050 13690034 YP_006767810.1 CDS rpoZ NC_018650.1 109892 110167 R COG1758 DNA-directed RNA polymerase, subunit K/omega; DNA-directed RNA polymerase subunit omega complement(109892..110167) Escherichia coli O104:H4 str. 2009EL-2050 13690035 YP_006767811.1 CDS gmk NC_018650.1 110222 110845 R COG0194 Guanylate kinase; guanylate kinase complement(110222..110845) Escherichia coli O104:H4 str. 2009EL-2050 13690036 YP_006767812.1 CDS ligB NC_018650.1 111103 112785 D COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase LigB 111103..112785 Escherichia coli O104:H4 str. 2009EL-2050 13690037 YP_006767813.1 CDS O3M_00640 NC_018650.1 112782 113399 R COG2860 Predicted membrane protein; hypothetical protein complement(112782..113399) Escherichia coli O104:H4 str. 2009EL-2050 13690038 YP_006767814.1 CDS dinD NC_018650.1 113691 114515 R DNA-damage-inducible protein D complement(113691..114515) Escherichia coli O104:H4 str. 2009EL-2050 13690039 YP_006767815.1 CDS O3M_00650 NC_018650.1 114736 115599 R COG1561 Uncharacterized stress-induced protein; hypothetical protein complement(114736..115599) Escherichia coli O104:H4 str. 2009EL-2050 13690040 YP_006767816.1 CDS rph NC_018650.1 115726 116442 D COG0689 RNase PH; ribonuclease PH 115726..116442 Escherichia coli O104:H4 str. 2009EL-2050 13690041 YP_006767817.1 CDS pyrE NC_018650.1 116508 117149 D COG0461 Orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 116508..117149 Escherichia coli O104:H4 str. 2009EL-2050 13690042 YP_006767818.1 CDS slmA NC_018650.1 117186 117782 R COG1309 Transcriptional regulator; division inhibitor protein complement(117186..117782) Escherichia coli O104:H4 str. 2009EL-2050 13690043 YP_006767819.1 CDS dut NC_018650.1 117889 118344 R COG0756 dUTPase; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(117889..118344) Escherichia coli O104:H4 str. 2009EL-2050 13690044 YP_006767820.1 CDS O3M_00675 NC_018650.1 118325 119545 R COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(118325..119545) Escherichia coli O104:H4 str. 2009EL-2050 13690045 YP_006767821.1 CDS O3M_00680 NC_018650.1 119717 120385 D COG2003 DNA repair proteins; hypothetical protein 119717..120385 Escherichia coli O104:H4 str. 2009EL-2050 13690046 YP_006767822.1 CDS rpmB NC_018650.1 120602 120838 D COG0227 Ribosomal protein L28; 50S ribosomal protein L28 120602..120838 Escherichia coli O104:H4 str. 2009EL-2050 13690047 YP_006767823.1 CDS rpmG NC_018650.1 120859 121026 D COG0267 Ribosomal protein L33; 50S ribosomal protein L33 120859..121026 Escherichia coli O104:H4 str. 2009EL-2050 13690048 YP_006767824.1 CDS O3M_00695 NC_018650.1 121124 121933 D COG0266 Formamidopyrimidine-DNA glycosylase; formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase 121124..121933 Escherichia coli O104:H4 str. 2009EL-2050 13690049 YP_006767825.1 CDS coaD NC_018650.1 121972 122451 R COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase complement(121972..122451) Escherichia coli O104:H4 str. 2009EL-2050 13690050 YP_006767826.1 CDS O3M_00705 NC_018650.1 122459 123736 R COG1519 3-deoxy-D-manno-octulosonic-acid transferase; 3-deoxy-D-manno-octulosonic-acid transferase complement(122459..123736) Escherichia coli O104:H4 str. 2009EL-2050 13690051 YP_006767827.1 CDS O3M_00710 NC_018650.1 124149 125207 D COG0859 ADP-heptose:LPS heptosyltransferase; lipopolysaccharide core biosynthesis protein 124149..125207 Escherichia coli O104:H4 str. 2009EL-2050 13690052 YP_006767828.1 CDS O3M_00715 NC_018650.1 125204 126328 D COG0438 Glycosyltransferase; glucosyltransferase I RfaG 125204..126328 Escherichia coli O104:H4 str. 2009EL-2050 13690053 YP_006767829.1 CDS O3M_00720 NC_018650.1 126321 127118 D COG0515 Serine/threonine protein kinase; lipopolysaccharide core heptose(I) kinase RfaP 126321..127118 Escherichia coli O104:H4 str. 2009EL-2050 13690054 YP_006767830.1 CDS O3M_00725 NC_018650.1 127161 128168 D COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,3-galactosyltransferase 127161..128168 Escherichia coli O104:H4 str. 2009EL-2050 13690055 YP_006767831.1 CDS O3M_00730 NC_018650.1 128194 128901 D COG0515 Serine/threonine protein kinase; lipopolysaccharide core biosynthesis protein 128194..128901 Escherichia coli O104:H4 str. 2009EL-2050 13690056 YP_006767832.1 CDS O3M_00735 NC_018650.1 128926 129939 D COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glucosyltransferase 128926..129939 Escherichia coli O104:H4 str. 2009EL-2050 13690057 YP_006767833.1 CDS O3M_00740 NC_018650.1 129948 131090 D COG0438 Glycosyltransferase; lipopolysaccharide 1,2-N-acetylglucosaminetransferase 129948..131090 Escherichia coli O104:H4 str. 2009EL-2050 13690058 YP_006767834.1 CDS O3M_00745 NC_018650.1 131126 132334 R COG3307 Lipid A core - O-antigen ligase and related enzymes; O-antigen ligase RfaL complement(131126..132334) Escherichia coli O104:H4 str. 2009EL-2050 13690059 YP_006767835.1 CDS O3M_00750 NC_018650.1 132331 133323 R COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose--LPS heptosyltransferase complement(132331..133323) Escherichia coli O104:H4 str. 2009EL-2050 13690060 YP_006767836.1 CDS O3M_00755 NC_018650.1 133327 134373 R COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose--LPS heptosyltransferase complement(133327..134373) Escherichia coli O104:H4 str. 2009EL-2050 13690061 YP_006767837.1 CDS rfaD NC_018650.1 134383 135315 R COG0451 Nucleoside-diphosphate-sugar epimerases; ADP-L-glycero-D-manno-heptose-6-epimerase complement(134383..135315) Escherichia coli O104:H4 str. 2009EL-2050 13690062 YP_006767838.1 CDS O3M_00765 NC_018650.1 135619 136476 D hypothetical protein 135619..136476 Escherichia coli O104:H4 str. 2009EL-2050 13690063 YP_006767839.1 CDS O3M_00770 NC_018650.1 136751 137947 D COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 2-amino-3-ketobutyrate coenzyme A ligase 136751..137947 Escherichia coli O104:H4 str. 2009EL-2050 13690064 YP_006767840.1 CDS tdh NC_018650.1 137957 138982 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; L-threonine 3-dehydrogenase 137957..138982 Escherichia coli O104:H4 str. 2009EL-2050 13690065 YP_006767841.1 CDS O3M_00780 NC_018650.1 139221 140255 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 139221..140255 Escherichia coli O104:H4 str. 2009EL-2050 13690066 YP_006767842.1 CDS O3M_00785 NC_018650.1 140242 141201 R COG2861 Uncharacterized protein conserved in bacteria; polysaccharide deacetylase complement(140242..141201) Escherichia coli O104:H4 str. 2009EL-2050 13690067 YP_006767843.1 CDS O3M_00790 NC_018650.1 141205 142488 R COG4942 Membrane-bound metallopeptidase; AmiB activator complement(141205..142488) Escherichia coli O104:H4 str. 2009EL-2050 13690068 YP_006767844.1 CDS O3M_00795 NC_018650.1 142498 144042 R COG0696 Phosphoglyceromutase; phosphoglyceromutase complement(142498..144042) Escherichia coli O104:H4 str. 2009EL-2050 13690069 YP_006767845.1 CDS O3M_00800 NC_018650.1 144287 144718 D COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 144287..144718 Escherichia coli O104:H4 str. 2009EL-2050 13690070 YP_006767846.1 CDS O3M_00805 NC_018650.1 144860 145111 D COG0695 Glutaredoxin and related proteins; glutaredoxin 3 144860..145111 Escherichia coli O104:H4 str. 2009EL-2050 13690071 YP_006767847.1 CDS O3M_00810 NC_018650.1 145174 145641 D COG1952 Preprotein translocase subunit SecB; preprotein translocase subunit SecB 145174..145641 Escherichia coli O104:H4 str. 2009EL-2050 13690072 YP_006767848.1 CDS gpsA NC_018650.1 145641 146660 D COG0240 Glycerol-3-phosphate dehydrogenase; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 145641..146660 Escherichia coli O104:H4 str. 2009EL-2050 13690073 YP_006767849.1 CDS cysE NC_018650.1 146740 147561 D COG1045 Serine acetyltransferase; serine acetyltransferase 146740..147561 Escherichia coli O104:H4 str. 2009EL-2050 13690074 YP_006767850.1 CDS O3M_00825 NC_018650.1 147614 148087 R COG0219 Predicted rRNA methylase (SpoU class); rRNA methylase complement(147614..148087) Escherichia coli O104:H4 str. 2009EL-2050 13690075 YP_006767851.1 CDS lldD NC_018650.1 148273 149463 R COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase complement(148273..149463) Escherichia coli O104:H4 str. 2009EL-2050 13690076 YP_006767852.1 CDS O3M_00835 NC_018650.1 149460 150236 R COG2186 Transcriptional regulators; DNA-binding transcriptional repressor LldR complement(149460..150236) Escherichia coli O104:H4 str. 2009EL-2050 13690077 YP_006767853.1 CDS O3M_00840 NC_018650.1 150236 151891 R COG1620 L-lactate permease; L-lactate permease complement(150236..151891) Escherichia coli O104:H4 str. 2009EL-2050 13690078 YP_006767854.1 CDS O3M_00845 NC_018650.1 152260 157110 R COG5295 Autotransporter adhesin; adhesin complement(152260..157110) Escherichia coli O104:H4 str. 2009EL-2050 13690079 YP_006767855.1 CDS O3M_00850 NC_018650.1 157154 157837 R hypothetical protein complement(157154..157837) Escherichia coli O104:H4 str. 2009EL-2050 13690080 YP_006767856.1 CDS O3M_00855 NC_018650.1 158381 158743 R hypothetical protein complement(158381..158743) Escherichia coli O104:H4 str. 2009EL-2050 13690081 YP_006767857.1 CDS O3M_00860 NC_018650.1 159028 159237 D hypothetical protein 159028..159237 Escherichia coli O104:H4 str. 2009EL-2050 13690082 YP_006767858.1 CDS mtlR NC_018650.1 159249 159836 R COG3722 Transcriptional regulator; mannitol repressor protein complement(159249..159836) Escherichia coli O104:H4 str. 2009EL-2050 13690083 YP_006767859.1 CDS O3M_00870 NC_018650.1 159836 160984 R COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannitol-1-phosphate 5-dehydrogenase complement(159836..160984) Escherichia coli O104:H4 str. 2009EL-2050 13690084 YP_006767860.1 CDS O3M_00875 NC_018650.1 161214 163127 R COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system mannitol-specific transporter subunit IICBA complement(161214..163127) Escherichia coli O104:H4 str. 2009EL-2050 13690085 YP_006767861.1 CDS O3M_00880 NC_018650.1 163664 164026 D hypothetical protein 163664..164026 Escherichia coli O104:H4 str. 2009EL-2050 13690086 YP_006767862.1 CDS O3M_00885 NC_018650.1 164029 165165 D COG1566 Multidrug resistance efflux pump; hypothetical protein 164029..165165 Escherichia coli O104:H4 str. 2009EL-2050 13690087 YP_006767863.1 CDS O3M_00890 NC_018650.1 166764 167225 R COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein complement(166764..167225) Escherichia coli O104:H4 str. 2009EL-2050 13690088 YP_006767864.1 CDS O3M_00895 NC_018650.1 167237 168181 R COG3209 Rhs family protein; Rhs family protein complement(167237..168181) Escherichia coli O104:H4 str. 2009EL-2050 13690089 YP_006767865.1 CDS O3M_00900 NC_018650.1 168223 169065 R COG1413 FOG: HEAT repeat; lyase complement(168223..169065) Escherichia coli O104:H4 str. 2009EL-2050 13690090 YP_006767866.1 CDS O3M_00905 NC_018650.1 169170 169553 R hypothetical protein complement(169170..169553) Escherichia coli O104:H4 str. 2009EL-2050 13690091 YP_006767867.1 CDS O3M_00910 NC_018650.1 169795 173760 R COG3209 Rhs family protein; rhsB element core protein RshB complement(169795..173760) Escherichia coli O104:H4 str. 2009EL-2050 13690092 YP_006767868.1 CDS O3M_00915 NC_018650.1 173989 174597 D COG0625 Glutathione S-transferase; glutathione S-transferase 173989..174597 Escherichia coli O104:H4 str. 2009EL-2050 13690093 YP_006767869.1 CDS O3M_00920 NC_018650.1 174695 176086 D COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; selenocysteine synthase 174695..176086 Escherichia coli O104:H4 str. 2009EL-2050 13690094 YP_006767870.1 CDS O3M_00925 NC_018650.1 176083 177927 D COG3276 Selenocysteine-specific translation elongation factor; selenocysteinyl-tRNA-specific translation factor 176083..177927 Escherichia coli O104:H4 str. 2009EL-2050 13690095 YP_006767871.1 CDS O3M_00930 NC_018650.1 178117 179268 D COG1454 Alcohol dehydrogenase, class IV; alcohol dehydrogenase 178117..179268 Escherichia coli O104:H4 str. 2009EL-2050 13690096 YP_006767872.1 CDS O3M_00935 NC_018650.1 179433 180971 D COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 179433..180971 Escherichia coli O104:H4 str. 2009EL-2050 13690097 YP_006767873.1 CDS O3M_00940 NC_018650.1 181190 181402 R hypothetical protein complement(181190..181402) Escherichia coli O104:H4 str. 2009EL-2050 13690098 YP_006767874.1 CDS O3M_00945 NC_018650.1 181516 181839 D hypothetical protein 181516..181839 Escherichia coli O104:H4 str. 2009EL-2050 13690099 YP_006767875.1 CDS O3M_00950 NC_018650.1 181845 182981 D COG1566 Multidrug resistance efflux pump; efflux pump membrane protein 181845..182981 Escherichia coli O104:H4 str. 2009EL-2050 13690100 YP_006767876.1 CDS O3M_00955 NC_018650.1 182978 183952 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator complement(182978..183952) Escherichia coli O104:H4 str. 2009EL-2050 13690101 YP_006767877.1 CDS O3M_00960 NC_018650.1 184076 184816 D COG3713 Outer membrane protein V; hypothetical protein 184076..184816 Escherichia coli O104:H4 str. 2009EL-2050 13690102 YP_006767878.1 CDS sgbE NC_018650.1 185163 185858 R COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase complement(185163..185858) Escherichia coli O104:H4 str. 2009EL-2050 13690103 YP_006767879.1 CDS O3M_00970 NC_018650.1 185852 186712 R COG3623 Putative L-xylulose-5-phosphate 3-epimerase; L-xylulose 5-phosphate 3-epimerase complement(185852..186712) Escherichia coli O104:H4 str. 2009EL-2050 13690104 YP_006767880.1 CDS sgbH NC_018650.1 186705 187367 R COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-keto-L-gulonate-6-phosphate decarboxylase complement(186705..187367) Escherichia coli O104:H4 str. 2009EL-2050 13690105 YP_006767881.1 CDS O3M_00980 NC_018650.1 187364 188860 R COG1070 Sugar (pentulose and hexulose) kinases; L-xylulose kinase complement(187364..188860) Escherichia coli O104:H4 str. 2009EL-2050 13690106 YP_006767882.1 CDS O3M_00985 NC_018650.1 188864 189850 R COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component; transporter complement(188864..189850) Escherichia coli O104:H4 str. 2009EL-2050 13690107 YP_006767883.1 CDS O3M_00990 NC_018650.1 189863 191140 R COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; L-dehydroascorbate transporter large permease subunit complement(189863..191140) Escherichia coli O104:H4 str. 2009EL-2050 13690108 YP_006767884.1 CDS O3M_00995 NC_018650.1 191143 191616 R COG3090 TRAP-type C4-dicarboxylate transport system, small permease component; 2,3-diketo-L-gulonate TRAP transporter small permease complement(191143..191616) Escherichia coli O104:H4 str. 2009EL-2050 13690109 YP_006767885.1 CDS O3M_01000 NC_018650.1 191734 192201 R COG2731 Beta-galactosidase, beta subunit; hypothetical protein complement(191734..192201) Escherichia coli O104:H4 str. 2009EL-2050 13690110 YP_006767886.1 CDS O3M_01005 NC_018650.1 192213 193211 R COG2055 Malate/L-lactate dehydrogenases; 2,3-diketo-L-gulonate reductase complement(192213..193211) Escherichia coli O104:H4 str. 2009EL-2050 13690111 YP_006767887.1 CDS O3M_01010 NC_018650.1 193412 194260 D COG1414 Transcriptional regulator; DNA-binding transcriptional repressor 193412..194260 Escherichia coli O104:H4 str. 2009EL-2050 13690112 YP_006767888.1 CDS O3M_01015 NC_018650.1 194362 194835 D COG1142 Fe-S-cluster-containing hydrogenase components 2; 4Fe-4S binding protein 194362..194835 Escherichia coli O104:H4 str. 2009EL-2050 13690113 YP_006767889.1 CDS O3M_01020 NC_018650.1 194855 194983 R hypothetical protein complement(194855..194983) Escherichia coli O104:H4 str. 2009EL-2050 13690114 YP_006767890.1 CDS avtA NC_018650.1 194987 196240 R COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; valine--pyruvate transaminase complement(194987..196240) Escherichia coli O104:H4 str. 2009EL-2050 13690115 YP_006767891.1 CDS O3M_01040 NC_018650.1 198767 199591 D COG2992 Uncharacterized FlgJ-related protein; hypothetical protein 198767..199591 Escherichia coli O104:H4 str. 2009EL-2050 13690116 YP_006767892.1 CDS O3M_01045 NC_018650.1 199787 200965 R COG1609 Transcriptional regulators; DNA-binding transcriptional activator, xylose-binding protein complement(199787..200965) Escherichia coli O104:H4 str. 2009EL-2050 13690117 YP_006767893.1 CDS O3M_01050 NC_018650.1 201043 202224 R COG4214 ABC-type xylose transport system, permease component; D-xylose ABC transporter permease complement(201043..202224) Escherichia coli O104:H4 str. 2009EL-2050 13690118 YP_006767894.1 CDS O3M_01055 NC_018650.1 202202 203743 R COG1129 ABC-type sugar transport system, ATPase component; xylose transporter ATP-binding subunit complement(202202..203743) Escherichia coli O104:H4 str. 2009EL-2050 13690119 YP_006767895.1 CDS xylF NC_018650.1 203821 204813 R COG4213 ABC-type xylose transport system, periplasmic component; D-xylose transporter subunit XylF complement(203821..204813) Escherichia coli O104:H4 str. 2009EL-2050 13690120 YP_006767896.1 CDS O3M_01065 NC_018650.1 205179 206501 D COG2115 Xylose isomerase; xylose isomerase 205179..206501 Escherichia coli O104:H4 str. 2009EL-2050 13690121 YP_006767897.1 CDS O3M_01070 NC_018650.1 206573 208027 D COG1070 Sugar (pentulose and hexulose) kinases; xylulokinase 206573..208027 Escherichia coli O104:H4 str. 2009EL-2050 13690122 YP_006767898.1 CDS O3M_01075 NC_018650.1 208196 208537 D COG4682 Predicted membrane protein; hypothetical protein 208196..208537 Escherichia coli O104:H4 str. 2009EL-2050 13690123 YP_006767899.1 CDS O3M_01080 NC_018650.1 208583 209020 D COG4682 Predicted membrane protein; hypothetical protein 208583..209020 Escherichia coli O104:H4 str. 2009EL-2050 13690124 YP_006767900.1 CDS O3M_01085 NC_018650.1 209062 210057 R COG3274 Uncharacterized protein conserved in bacteria; hypothetical protein complement(209062..210057) Escherichia coli O104:H4 str. 2009EL-2050 13690125 YP_006767901.1 CDS O3M_01090 NC_018650.1 210232 210531 D outer membrane lipoprotein 210232..210531 Escherichia coli O104:H4 str. 2009EL-2050 13690126 YP_006767902.1 CDS glyQ NC_018650.1 210626 211537 D COG0752 Glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA synthetase subunit alpha 210626..211537 Escherichia coli O104:H4 str. 2009EL-2050 13690127 YP_006767903.1 CDS glyS NC_018650.1 211547 213616 D COG0751 Glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase subunit beta 211547..213616 Escherichia coli O104:H4 str. 2009EL-2050 13690128 YP_006767904.1 CDS O3M_01105 NC_018650.1 213882 214094 D small toxic polypeptide 213882..214094 Escherichia coli O104:H4 str. 2009EL-2050 13690129 YP_006767905.1 CDS O3M_01110 NC_018650.1 214282 214494 R COG1278 Cold shock proteins; RNA chaperone/anti-terminator complement(214282..214494) Escherichia coli O104:H4 str. 2009EL-2050 13690130 YP_006767906.1 CDS O3M_01115 NC_018650.1 214775 215065 R COG2944 Predicted transcriptional regulator; transcriptional regulator complement(214775..215065) Escherichia coli O104:H4 str. 2009EL-2050 13690131 YP_006767907.1 CDS O3M_01120 NC_018650.1 215499 216209 D hypothetical protein 215499..216209 Escherichia coli O104:H4 str. 2009EL-2050 13690132 YP_006767908.1 CDS O3M_01125 NC_018650.1 216259 217233 R COG1052 Lactate dehydrogenase and related dehydrogenases; bifunctional glyoxylate/hydroxypyruvate reductase B complement(216259..217233) Escherichia coli O104:H4 str. 2009EL-2050 13690133 YP_006767909.1 CDS O3M_01130 NC_018650.1 217337 217996 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; outer membrane lipoprotein complement(217337..217996) Escherichia coli O104:H4 str. 2009EL-2050 13690134 YP_006767910.1 CDS O3M_01135 NC_018650.1 218149 220482 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; biotin sulfoxide reductase 218149..220482 Escherichia coli O104:H4 str. 2009EL-2050 13690135 YP_006767911.1 CDS O3M_01140 NC_018650.1 220451 220891 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase complement(220451..220891) Escherichia coli O104:H4 str. 2009EL-2050 13690136 YP_006767912.1 CDS O3M_01145 NC_018650.1 220888 221451 R COG2818 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase complement(220888..221451) Escherichia coli O104:H4 str. 2009EL-2050 13690785 YP_006767913.1 CDS O3M_01150 NC_018650.1 221609 222307 D hypothetical protein 221609..222307 Escherichia coli O104:H4 str. 2009EL-2050 13690786 YP_006767914.1 CDS O3M_01155 NC_018650.1 222536 223738 D COG0477 Permeases of the major facilitator superfamily; transporter 222536..223738 Escherichia coli O104:H4 str. 2009EL-2050 13690787 YP_006767915.1 CDS O3M_01160 NC_018650.1 224062 224586 D COG3539 P pilus assembly protein, pilin FimA; long polar fimbrial protein LpfA 224062..224586 Escherichia coli O104:H4 str. 2009EL-2050 13690788 YP_006767916.1 CDS O3M_01165 NC_018650.1 224670 225356 D COG3121 P pilus assembly protein, chaperone PapD; long polar fimbrial chaperone LpfB 224670..225356 Escherichia coli O104:H4 str. 2009EL-2050 13690789 YP_006767917.1 CDS O3M_01170 NC_018650.1 225380 227911 D COG3188 P pilus assembly protein, porin PapC; long polar fimbrial outer membrane usher protein LpfC 225380..227911 Escherichia coli O104:H4 str. 2009EL-2050 13690790 YP_006767918.1 CDS O3M_01175 NC_018650.1 227922 228977 D long polar fimbrial protein LpfD 227922..228977 Escherichia coli O104:H4 str. 2009EL-2050 13690791 YP_006767919.1 CDS O3M_01180 NC_018650.1 228983 229507 D COG3539 P pilus assembly protein, pilin FimA; long polar fimbrial protein LpfE 228983..229507 Escherichia coli O104:H4 str. 2009EL-2050 13690792 YP_006767920.1 CDS O3M_01185 NC_018650.1 229760 231451 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; phosphoethanolamine transferase 229760..231451 Escherichia coli O104:H4 str. 2009EL-2050 13690793 YP_006767921.1 CDS O3M_01190 NC_018650.1 232363 233970 D COG0747 ABC-type dipeptide transport system, periplasmic component; dipeptide transport protein 232363..233970 Escherichia coli O104:H4 str. 2009EL-2050 13690795 YP_006767922.1 CDS O3M_01195 NC_018650.1 234121 235140 D COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide transporter permease DppB 234121..235140 Escherichia coli O104:H4 str. 2009EL-2050 13690796 YP_006767923.1 CDS O3M_01200 NC_018650.1 235150 236052 D COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide transporter 235150..236052 Escherichia coli O104:H4 str. 2009EL-2050 13690797 YP_006767924.1 CDS dppD NC_018650.1 236063 237046 D COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; dipeptide transporter ATP-binding subunit 236063..237046 Escherichia coli O104:H4 str. 2009EL-2050 13690798 YP_006767925.1 CDS dppF NC_018650.1 237043 238047 D COG4608 ABC-type oligopeptide transport system, ATPase component; dipeptide transporter ATP-binding subunit 237043..238047 Escherichia coli O104:H4 str. 2009EL-2050 13690799 YP_006767926.1 CDS O3M_01215 NC_018650.1 238077 239348 R COG0814 Amino acid permeases; transporter complement(238077..239348) Escherichia coli O104:H4 str. 2009EL-2050 13690800 YP_006767927.1 CDS O3M_01220 NC_018650.1 240306 240413 D toxic polypeptide, small 240306..240413 Escherichia coli O104:H4 str. 2009EL-2050 13690801 YP_006767928.1 CDS O3M_01225 NC_018650.1 240789 240896 D toxic polypeptide, small 240789..240896 Escherichia coli O104:H4 str. 2009EL-2050 13690802 YP_006767929.1 CDS O3M_01230 NC_018650.1 240983 242662 R hypothetical protein complement(240983..242662) Escherichia coli O104:H4 str. 2009EL-2050 13690803 YP_006767930.1 CDS O3M_01235 NC_018650.1 242659 242850 R hypothetical protein complement(242659..242850) Escherichia coli O104:H4 str. 2009EL-2050 13690804 YP_006767931.1 CDS O3M_01250 NC_018650.1 244692 244880 D hypothetical protein 244692..244880 Escherichia coli O104:H4 str. 2009EL-2050 13690805 YP_006767932.1 CDS O3M_01255 NC_018650.1 244892 245644 D COG1192 ATPases involved in chromosome partitioning; cell division protein 244892..245644 Escherichia coli O104:H4 str. 2009EL-2050 13690806 YP_006767933.1 CDS bcsA NC_018650.1 245641 248259 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; cellulose synthase catalytic subunit 245641..248259 Escherichia coli O104:H4 str. 2009EL-2050 13690807 YP_006767934.1 CDS O3M_01265 NC_018650.1 248270 250609 D cellulose synthase regulator protein 248270..250609 Escherichia coli O104:H4 str. 2009EL-2050 13690808 YP_006767935.1 CDS O3M_01270 NC_018650.1 250616 251722 D COG3405 Endoglucanase Y; endo-1,4-D-glucanase 250616..251722 Escherichia coli O104:H4 str. 2009EL-2050 13690809 YP_006767936.1 CDS O3M_01275 NC_018650.1 251704 255177 D COG0457 FOG: TPR repeat; cellulose synthase subunit BcsC 251704..255177 Escherichia coli O104:H4 str. 2009EL-2050 13690810 YP_006767937.1 CDS O3M_01280 NC_018650.1 255292 257247 D COG2199 FOG: GGDEF domain; diguanylate cyclase 255292..257247 Escherichia coli O104:H4 str. 2009EL-2050 13690811 YP_006767938.1 CDS O3M_01285 NC_018650.1 257430 258716 D COG1301 Na+/H+-dicarboxylate symporters; C4-dicarboxylate transporter DctA 257430..258716 Escherichia coli O104:H4 str. 2009EL-2050 13690812 YP_006767939.1 CDS O3M_01290 NC_018650.1 258937 260433 D COG0612 Predicted Zn-dependent peptidases; zinc-dependent peptidase 258937..260433 Escherichia coli O104:H4 str. 2009EL-2050 13690813 YP_006767940.1 CDS O3M_01295 NC_018650.1 260529 261458 R COG0524 Sugar kinases, ribokinase family; ketodeoxygluconokinase complement(260529..261458) Escherichia coli O104:H4 str. 2009EL-2050 13690814 YP_006767941.1 CDS O3M_01300 NC_018650.1 261690 262457 D COG2200 FOG: EAL domain; cyclic-di-GMP phosphodiesterase 261690..262457 Escherichia coli O104:H4 str. 2009EL-2050 13690815 YP_006767942.1 CDS O3M_01305 NC_018650.1 262527 264587 D COG2982 Uncharacterized protein involved in outer membrane biogenesis; outer membrane biogenesis protein 262527..264587 Escherichia coli O104:H4 str. 2009EL-2050 13690816 YP_006767943.1 CDS O3M_01310 NC_018650.1 264821 266143 R COG0477 Permeases of the major facilitator superfamily; inner membrane metabolite transport protein yhjE complement(264821..266143) Escherichia coli O104:H4 str. 2009EL-2050 13690817 YP_006767944.1 CDS O3M_01315 NC_018650.1 266554 267567 R COG1295 Predicted membrane protein; ribonuclease complement(266554..267567) Escherichia coli O104:H4 str. 2009EL-2050 13690818 YP_006767945.1 CDS O3M_01320 NC_018650.1 267616 268587 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator complement(267616..268587) Escherichia coli O104:H4 str. 2009EL-2050 13690819 YP_006767946.1 CDS O3M_01325 NC_018650.1 269035 269637 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; HTH-type transcriptional regulator yhjB 269035..269637 Escherichia coli O104:H4 str. 2009EL-2050 13690820 YP_006767947.1 CDS treF NC_018650.1 269688 271337 R COG1626 Neutral trehalase; trehalase complement(269688..271337) Escherichia coli O104:H4 str. 2009EL-2050 13690821 YP_006767948.1 CDS O3M_01335 NC_018650.1 271742 273139 D COG1858 Cytochrome c peroxidase; cytochrome C peroxidase 271742..273139 Escherichia coli O104:H4 str. 2009EL-2050 13690822 YP_006767949.1 CDS O3M_01340 NC_018650.1 273350 274750 D COG0076 Glutamate decarboxylase and related PLP-dependent proteins; glutamate decarboxylase 273350..274750 Escherichia coli O104:H4 str. 2009EL-2050 13690823 YP_006767950.1 CDS O3M_01345 NC_018650.1 275120 275944 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator GadX 275120..275944 Escherichia coli O104:H4 str. 2009EL-2050 13690824 YP_006767951.1 CDS O3M_01350 NC_018650.1 276312 277040 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator GadW 276312..277040 Escherichia coli O104:H4 str. 2009EL-2050 13690825 YP_006767952.1 CDS O3M_01355 NC_018650.1 277403 280516 R COG0841 Cation/multidrug efflux pump; multidrug transporter MdtF, RpoS-dependent complement(277403..280516) Escherichia coli O104:H4 str. 2009EL-2050 13690826 YP_006767953.1 CDS O3M_01360 NC_018650.1 280541 281698 R COG0845 Membrane-fusion protein; multidrug efflux system protein MdtE complement(280541..281698) Escherichia coli O104:H4 str. 2009EL-2050 13690827 YP_006767954.1 CDS O3M_01365 NC_018650.1 281604 281720 D hypothetical protein 281604..281720 Escherichia coli O104:H4 str. 2009EL-2050 13690828 YP_006767955.1 CDS O3M_01370 NC_018650.1 281758 282036 D hypothetical protein 281758..282036 Escherichia coli O104:H4 str. 2009EL-2050 13690829 YP_006767956.1 CDS O3M_01375 NC_018650.1 282037 282564 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator complement(282037..282564) Escherichia coli O104:H4 str. 2009EL-2050 13690830 YP_006767957.1 CDS O3M_01380 NC_018650.1 283363 283935 R COG3247 Uncharacterized conserved protein; acid-resistance membrane protein complement(283363..283935) Escherichia coli O104:H4 str. 2009EL-2050 13690831 YP_006767958.1 CDS O3M_01385 NC_018650.1 284190 284522 D acid-resistance protein 284190..284522 Escherichia coli O104:H4 str. 2009EL-2050 13690832 YP_006767959.1 CDS hdeB NC_018650.1 284626 284964 D acid-resistance protein 284626..284964 Escherichia coli O104:H4 str. 2009EL-2050 13690833 YP_006767960.1 CDS O3M_01395 NC_018650.1 285028 285675 D COG1285 Uncharacterized membrane protein; Mg(2+) transport ATPase 285028..285675 Escherichia coli O104:H4 str. 2009EL-2050 13690834 YP_006767961.1 CDS O3M_01400 NC_018650.1 285717 286247 R COG0055 F0F1-type ATP synthase, beta subunit; DNA-binding transcriptional regulator complement(285717..286247) Escherichia coli O104:H4 str. 2009EL-2050 13690835 YP_006767962.1 CDS O3M_01405 NC_018650.1 286403 286969 R COG3065 Starvation-inducible outer membrane lipoprotein; outer membrane lipoprotein complement(286403..286969) Escherichia coli O104:H4 str. 2009EL-2050 13690836 YP_006767963.1 CDS O3M_01410 NC_018650.1 287293 288438 R COG1518 Uncharacterized protein predicted to be involved in DNA repair; hypothetical protein complement(287293..288438) Escherichia coli O104:H4 str. 2009EL-2050 13690837 YP_006767964.1 CDS O3M_01415 NC_018650.1 289018 290031 R COG0701 Predicted permeases; hypothetical protein complement(289018..290031) Escherichia coli O104:H4 str. 2009EL-2050 13690838 YP_006767965.1 CDS O3M_01420 NC_018650.1 290138 290434 D COG0640 Predicted transcriptional regulators; hypothetical protein 290138..290434 Escherichia coli O104:H4 str. 2009EL-2050 13690839 YP_006767966.1 CDS O3M_01425 NC_018650.1 290568 290993 R COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase complement(290568..290993) Escherichia coli O104:H4 str. 2009EL-2050 13690840 YP_006767967.1 CDS O3M_01430 NC_018650.1 291006 292295 R COG1055 Na+/H+ antiporter NhaD and related arsenite permeases; arsenical pump membrane protein complement(291006..292295) Escherichia coli O104:H4 str. 2009EL-2050 13690841 YP_006767968.1 CDS O3M_01435 NC_018650.1 292349 292702 R COG0640 Predicted transcriptional regulators; DNA-binding transcriptional repressor ArsR complement(292349..292702) Escherichia coli O104:H4 str. 2009EL-2050 13690842 YP_006767969.1 CDS O3M_01440 NC_018650.1 293376 293525 D hypothetical protein 293376..293525 Escherichia coli O104:H4 str. 2009EL-2050 13690843 YP_006767970.1 CDS O3M_01445 NC_018650.1 293579 294931 R COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; glutathione reductase complement(293579..294931) Escherichia coli O104:H4 str. 2009EL-2050 13690844 YP_006767971.1 CDS O3M_01450 NC_018650.1 295003 295845 R COG2961 Protein involved in catabolism of external DNA; DNA processing protein complement(295003..295845) Escherichia coli O104:H4 str. 2009EL-2050 13690845 YP_006767972.1 CDS O3M_01455 NC_018650.1 296048 298090 D COG0339 Zn-dependent oligopeptidases; oligopeptidase A 296048..298090 Escherichia coli O104:H4 str. 2009EL-2050 13690846 YP_006767973.1 CDS O3M_01460 NC_018650.1 298098 298850 D COG0500 SAM-dependent methyltransferases; methyltransferase 298098..298850 Escherichia coli O104:H4 str. 2009EL-2050 13690847 YP_006767974.1 CDS O3M_01465 NC_018650.1 298899 300368 R COG3104 Dipeptide/tripeptide permease; dipeptide/tripeptide permease B complement(298899..300368) Escherichia coli O104:H4 str. 2009EL-2050 13690848 YP_006767975.1 CDS O3M_01470 NC_018650.1 300686 301120 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress global response regulator UspA complement(300686..301120) Escherichia coli O104:H4 str. 2009EL-2050 13690849 YP_006767976.1 CDS O3M_01475 NC_018650.1 301511 301846 D universal stress protein UspB 301511..301846 Escherichia coli O104:H4 str. 2009EL-2050 13690850 YP_006767977.1 CDS O3M_01480 NC_018650.1 301917 303416 R COG0306 Phosphate/sulphate permeases; Low-affinity inorganic phosphate transporter 1 complement(301917..303416) Escherichia coli O104:H4 str. 2009EL-2050 13690851 YP_006767978.1 CDS O3M_01485 NC_018650.1 303648 304850 D COG2081 Predicted flavoproteins; oxidoreductase with FAD/NAD(P)-binding domain 303648..304850 Escherichia coli O104:H4 str. 2009EL-2050 13690852 YP_006767979.1 CDS O3M_01490 NC_018650.1 304993 305835 D Tn7-like transposase TnsA 304993..305835 Escherichia coli O104:H4 str. 2009EL-2050 13690853 YP_006767980.1 CDS O3M_01495 NC_018650.1 305822 307945 D COG2801 Transposase and inactivated derivatives; Tn7-like transposition protein TnsB 305822..307945 Escherichia coli O104:H4 str. 2009EL-2050 13690854 YP_006767981.1 CDS O3M_01500 NC_018650.1 307945 309393 D COG1132 ABC-type multidrug transport system, ATPase and permease components; Tn7-like transposition protein TnsC 307945..309393 Escherichia coli O104:H4 str. 2009EL-2050 13690855 YP_006767982.1 CDS O3M_01505 NC_018650.1 309425 310990 D TnsD 309425..310990 Escherichia coli O104:H4 str. 2009EL-2050 13690856 YP_006767983.1 CDS O3M_01510 NC_018650.1 311002 311223 D hypothetical protein 311002..311223 Escherichia coli O104:H4 str. 2009EL-2050 13690857 YP_006767984.1 CDS O3M_01515 NC_018650.1 311227 312840 R COG3436 Transposase and inactivated derivatives; transposase complement(311227..312840) Escherichia coli O104:H4 str. 2009EL-2050 13690858 YP_006767985.1 CDS O3M_01520 NC_018650.1 312871 313221 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(312871..313221) Escherichia coli O104:H4 str. 2009EL-2050 13690859 YP_006767986.1 CDS O3M_01525 NC_018650.1 313218 313652 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(313218..313652) Escherichia coli O104:H4 str. 2009EL-2050 13690860 YP_006767987.1 CDS O3M_01530 NC_018650.1 314169 314477 D hypothetical protein 314169..314477 Escherichia coli O104:H4 str. 2009EL-2050 13690861 YP_006767988.1 CDS O3M_01535 NC_018650.1 314830 315129 D COG1396 Predicted transcriptional regulators; transcriptional regulator 314830..315129 Escherichia coli O104:H4 str. 2009EL-2050 13690862 YP_006767989.1 CDS O3M_01540 NC_018650.1 315693 317519 D COG3593 Predicted ATP-dependent endonuclease of the OLD family; hypothetical protein 315693..317519 Escherichia coli O104:H4 str. 2009EL-2050 13690863 YP_006767990.1 CDS O3M_01545 NC_018650.1 317688 318038 R COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein complement(317688..318038) Escherichia coli O104:H4 str. 2009EL-2050 13690864 YP_006767991.1 CDS O3M_01550 NC_018650.1 318186 318734 R silver-binding protein SilE complement(318186..318734) Escherichia coli O104:H4 str. 2009EL-2050 13690865 YP_006767992.1 CDS O3M_01555 NC_018650.1 318862 320343 R COG0642 Signal transduction histidine kinase; sensor kinase CusS complement(318862..320343) Escherichia coli O104:H4 str. 2009EL-2050 13690866 YP_006767993.1 CDS O3M_01560 NC_018650.1 320336 321016 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator CusR complement(320336..321016) Escherichia coli O104:H4 str. 2009EL-2050 13690867 YP_006767994.1 CDS O3M_01565 NC_018650.1 321206 322591 D COG1538 Outer membrane protein; copper/silver efflux system outer membrane protein CusC 321206..322591 Escherichia coli O104:H4 str. 2009EL-2050 13690868 YP_006767995.1 CDS O3M_01570 NC_018650.1 322619 322972 D COG5569 Uncharacterized conserved protein; copper-binding protein 322619..322972 Escherichia coli O104:H4 str. 2009EL-2050 13690869 YP_006767996.1 CDS O3M_01575 NC_018650.1 323086 324378 D COG0845 Membrane-fusion protein; copper/silver efflux system membrane fusion protein CusB 323086..324378 Escherichia coli O104:H4 str. 2009EL-2050 13690870 YP_006767997.1 CDS O3M_01580 NC_018650.1 324389 327535 D COG3696 Putative silver efflux pump; Cu(I)/Ag(I) efflux system membrane protein CusA 324389..327535 Escherichia coli O104:H4 str. 2009EL-2050 13690871 YP_006767998.1 CDS O3M_01585 NC_018650.1 327622 328062 D COG3019 Predicted metal-binding protein; hypothetical protein 327622..328062 Escherichia coli O104:H4 str. 2009EL-2050 13690872 YP_006767999.1 CDS O3M_01590 NC_018650.1 328189 330636 D COG2217 Cation transport ATPase; cation-transporting P-type ATPase 328189..330636 Escherichia coli O104:H4 str. 2009EL-2050 13690873 YP_006768000.1 CDS O3M_01595 NC_018650.1 330677 330874 D hypothetical protein 330677..330874 Escherichia coli O104:H4 str. 2009EL-2050 13690874 YP_006768001.1 CDS O3M_01600 NC_018650.1 330908 331645 R COG0739 Membrane proteins related to metalloendopeptidases; peptidase complement(330908..331645) Escherichia coli O104:H4 str. 2009EL-2050 13690875 YP_006768002.1 CDS O3M_01605 NC_018650.1 331738 331824 D hypothetical protein 331738..331824 Escherichia coli O104:H4 str. 2009EL-2050 13690876 YP_006768003.1 CDS O3M_01610 NC_018650.1 331934 332383 R copper resistant protein PcoE complement(331934..332383) Escherichia coli O104:H4 str. 2009EL-2050 13690877 YP_006768004.1 CDS O3M_01615 NC_018650.1 332618 334435 D COG2132 Putative multicopper oxidases; copper resistant protein PcoA 332618..334435 Escherichia coli O104:H4 str. 2009EL-2050 13690878 YP_006768005.1 CDS O3M_01620 NC_018650.1 334432 335331 D COG3667 Uncharacterized protein involved in copper resistance; copper resistance protein B 334432..335331 Escherichia coli O104:H4 str. 2009EL-2050 13690879 YP_006768006.1 CDS O3M_01625 NC_018650.1 335371 335751 D COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; copper resistant protein PcoC 335371..335751 Escherichia coli O104:H4 str. 2009EL-2050 13690880 YP_006768007.1 CDS O3M_01630 NC_018650.1 335756 336685 D COG1276 Putative copper export protein; copper resistance protein D 335756..336685 Escherichia coli O104:H4 str. 2009EL-2050 13690881 YP_006768008.1 CDS O3M_01635 NC_018650.1 336740 337420 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator PcoR 336740..337420 Escherichia coli O104:H4 str. 2009EL-2050 13690882 YP_006768009.1 CDS O3M_01640 NC_018650.1 337417 338817 D COG0642 Signal transduction histidine kinase; sensor protein pcoS 337417..338817 Escherichia coli O104:H4 str. 2009EL-2050 13690883 YP_006768010.1 CDS O3M_01645 NC_018650.1 339035 339469 D copper-binding protein 339035..339469 Escherichia coli O104:H4 str. 2009EL-2050 13690884 YP_006768011.1 CDS O3M_01650 NC_018650.1 340129 341181 R hypothetical protein complement(340129..341181) Escherichia coli O104:H4 str. 2009EL-2050 13690885 YP_006768012.1 CDS O3M_01655 NC_018650.1 341566 342651 D hypothetical protein 341566..342651 Escherichia coli O104:H4 str. 2009EL-2050 13690886 YP_006768013.1 CDS O3M_01660 NC_018650.1 342819 343190 D hypothetical protein 342819..343190 Escherichia coli O104:H4 str. 2009EL-2050 13690887 YP_006768014.1 CDS O3M_01675 NC_018650.1 345439 346506 D COG0845 Membrane-fusion protein; HlyD family secretion protein 345439..346506 Escherichia coli O104:H4 str. 2009EL-2050 13690888 YP_006768015.1 CDS O3M_01680 NC_018650.1 346503 349238 D ATP-binding protein; ATP-binding protein; membrane protein; COG1131 ABC-type multidrug transport system, ATPase component; ribosome-associated ATPase 346503..349238 Escherichia coli O104:H4 str. 2009EL-2050 13690889 YP_006768016.1 CDS O3M_01685 NC_018650.1 349238 350362 D COG0842 ABC-type multidrug transport system, permease component; transporter subunit 349238..350362 Escherichia coli O104:H4 str. 2009EL-2050 13690890 YP_006768017.1 CDS O3M_01690 NC_018650.1 350693 351052 D COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters; HicB family protein 350693..351052 Escherichia coli O104:H4 str. 2009EL-2050 13690891 YP_006768018.1 CDS O3M_01695 NC_018650.1 351172 351573 R COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; nickel responsive regulator complement(351172..351573) Escherichia coli O104:H4 str. 2009EL-2050 13690892 YP_006768019.1 CDS nikE NC_018650.1 351579 352385 R COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; nickel transporter ATP-binding protein NikE complement(351579..352385) Escherichia coli O104:H4 str. 2009EL-2050 13690893 YP_006768020.1 CDS nikD NC_018650.1 352382 353146 R COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; nickel transporter ATP-binding protein NikD complement(352382..353146) Escherichia coli O104:H4 str. 2009EL-2050 13690894 YP_006768021.1 CDS nikC NC_018650.1 353146 353979 R COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; nickel transporter permease NikC complement(353146..353979) Escherichia coli O104:H4 str. 2009EL-2050 13690895 YP_006768022.1 CDS O3M_01715 NC_018650.1 353976 354920 R COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; nickel transporter permease NikB complement(353976..354920) Escherichia coli O104:H4 str. 2009EL-2050 13690896 YP_006768023.1 CDS O3M_01720 NC_018650.1 354920 356494 R COG0747 ABC-type dipeptide transport system, periplasmic component; periplasmic binding protein for nickel NikA complement(354920..356494) Escherichia coli O104:H4 str. 2009EL-2050 13690897 YP_006768024.1 CDS O3M_01725 NC_018650.1 356605 357192 R COG2091 Phosphopantetheinyl transferase; holo-(acyl carrier protein) synthase 2 complement(356605..357192) Escherichia coli O104:H4 str. 2009EL-2050 13690898 YP_006768025.1 CDS O3M_01730 NC_018650.1 357247 358296 R COG0628 Predicted permease; inner membrane protein complement(357247..358296) Escherichia coli O104:H4 str. 2009EL-2050 13690899 YP_006768026.1 CDS O3M_01735 NC_018650.1 358428 359645 D COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily transporter 358428..359645 Escherichia coli O104:H4 str. 2009EL-2050 13690900 YP_006768027.1 CDS O3M_01740 NC_018650.1 359649 360206 R hypothetical protein complement(359649..360206) Escherichia coli O104:H4 str. 2009EL-2050 13690901 YP_006768028.1 CDS O3M_01745 NC_018650.1 360279 360944 R COG1738 Uncharacterized conserved protein; hypothetical protein complement(360279..360944) Escherichia coli O104:H4 str. 2009EL-2050 13690902 YP_006768029.1 CDS O3M_01750 NC_018650.1 361165 361410 D COG0425 Predicted redox protein, regulator of disulfide bond formation; sulfur transfer protein SirA 361165..361410 Escherichia coli O104:H4 str. 2009EL-2050 13690903 YP_006768030.1 CDS zntA NC_018650.1 361512 363710 R COG2217 Cation transport ATPase; zinc/cadmium/mercury/lead-transporting ATPase complement(361512..363710) Escherichia coli O104:H4 str. 2009EL-2050 13690904 YP_006768031.1 CDS O3M_01760 NC_018650.1 363784 364410 R COG3714 Predicted membrane protein; hypothetical protein complement(363784..364410) Escherichia coli O104:H4 str. 2009EL-2050 13690905 YP_006768032.1 CDS O3M_01765 NC_018650.1 364551 364910 D hypothetical protein 364551..364910 Escherichia coli O104:H4 str. 2009EL-2050 13690906 YP_006768033.1 CDS O3M_01770 NC_018650.1 364913 365182 R COG3776 Predicted membrane protein; hypothetical protein complement(364913..365182) Escherichia coli O104:H4 str. 2009EL-2050 13690907 YP_006768034.1 CDS rsmD NC_018650.1 365172 365768 R COG0742 N6-adenine-specific methylase; 16S rRNA m(2)G966-methyltransferase complement(365172..365768) Escherichia coli O104:H4 str. 2009EL-2050 13690908 YP_006768035.1 CDS O3M_01780 NC_018650.1 365918 367411 D COG0552 Signal recognition particle GTPase; signal recognition particle-docking protein FtsY 365918..367411 Escherichia coli O104:H4 str. 2009EL-2050 13690909 YP_006768036.1 CDS O3M_01785 NC_018650.1 367414 368082 D COG2884 Predicted ATPase involved in cell division; cell division protein FtsE 367414..368082 Escherichia coli O104:H4 str. 2009EL-2050 13690910 YP_006768037.1 CDS ftsX NC_018650.1 368075 369133 D COG2177 Cell division protein; cell division ABC transporter subunit FtsX 368075..369133 Escherichia coli O104:H4 str. 2009EL-2050 13690911 YP_006768038.1 CDS O3M_01795 NC_018650.1 369378 370232 D COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase factor sigma-32 369378..370232 Escherichia coli O104:H4 str. 2009EL-2050 13690912 YP_006768039.1 CDS O3M_01800 NC_018650.1 370503 371606 D COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; leucine ABC transporter subunit substrate-binding protein LivK 370503..371606 Escherichia coli O104:H4 str. 2009EL-2050 13690913 YP_006768040.1 CDS O3M_01805 NC_018650.1 371662 371796 R hypothetical protein complement(371662..371796) Escherichia coli O104:H4 str. 2009EL-2050 13690914 YP_006768041.1 CDS O3M_01810 NC_018650.1 371805 372188 R hypothetical protein complement(371805..372188) Escherichia coli O104:H4 str. 2009EL-2050 13690915 YP_006768042.1 CDS O3M_01815 NC_018650.1 372612 373721 D COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; leucine ABC transporter subunit substrate-binding protein LivK 372612..373721 Escherichia coli O104:H4 str. 2009EL-2050 13690916 YP_006768043.1 CDS O3M_01820 NC_018650.1 373769 374695 D COG0559 Branched-chain amino acid ABC-type transport system, permease components; branched-chain amino acid transporter permease LivH 373769..374695 Escherichia coli O104:H4 str. 2009EL-2050 13690917 YP_006768044.1 CDS livM NC_018650.1 374692 375969 D COG4177 ABC-type branched-chain amino acid transport system, permease component; leucine/isoleucine/valine transporter permease subunit 374692..375969 Escherichia coli O104:H4 str. 2009EL-2050 13690918 YP_006768045.1 CDS livG NC_018650.1 375966 376733 D COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; leucine/isoleucine/valine transporter ATP-binding subunit 375966..376733 Escherichia coli O104:H4 str. 2009EL-2050 13690919 YP_006768046.1 CDS livF NC_018650.1 376747 377448 D COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; leucine/isoleucine/valine transporter ATP-binding subunit 376747..377448 Escherichia coli O104:H4 str. 2009EL-2050 13690920 YP_006768047.1 CDS O3M_01840 NC_018650.1 377484 377612 D hypothetical protein 377484..377612 Escherichia coli O104:H4 str. 2009EL-2050 13690921 YP_006768048.1 CDS O3M_01845 NC_018650.1 377844 379160 D COG1653 ABC-type sugar transport system, periplasmic component; glycerol-3-phosphate transporter periplasmic binding protein 377844..379160 Escherichia coli O104:H4 str. 2009EL-2050 13690922 YP_006768049.1 CDS O3M_01850 NC_018650.1 379258 380145 D COG1175 ABC-type sugar transport systems, permease components; glycerol-3-phosphate transporter permease 379258..380145 Escherichia coli O104:H4 str. 2009EL-2050 13690923 YP_006768050.1 CDS O3M_01855 NC_018650.1 380142 380987 D COG0395 ABC-type sugar transport system, permease component; glycerol-3-phosphate transporter membrane protein 380142..380987 Escherichia coli O104:H4 str. 2009EL-2050 13690924 YP_006768051.1 CDS ugpC NC_018650.1 380989 382059 D COG3839 ABC-type sugar transport systems, ATPase components; glycerol-3-phosphate transporter ATP-binding subunit 380989..382059 Escherichia coli O104:H4 str. 2009EL-2050 13690925 YP_006768052.1 CDS ugpQ NC_018650.1 382056 382799 D COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphodiester phosphodiesterase 382056..382799 Escherichia coli O104:H4 str. 2009EL-2050 13690926 YP_006768053.1 CDS O3M_01870 NC_018650.1 382786 383226 R hypothetical protein complement(382786..383226) Escherichia coli O104:H4 str. 2009EL-2050 13690927 YP_006768054.1 CDS ggt NC_018650.1 383346 385088 D COG0405 Gamma-glutamyltransferase; gamma-glutamyltranspeptidase 383346..385088 Escherichia coli O104:H4 str. 2009EL-2050 13690928 YP_006768055.1 CDS O3M_01880 NC_018650.1 385126 385410 R hypothetical protein complement(385126..385410) Escherichia coli O104:H4 str. 2009EL-2050 13690929 YP_006768056.1 CDS O3M_01885 NC_018650.1 385860 386354 R hypothetical protein complement(385860..386354) Escherichia coli O104:H4 str. 2009EL-2050 13690930 YP_006768057.1 CDS O3M_01890 NC_018650.1 386351 387529 R COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein complement(386351..387529) Escherichia coli O104:H4 str. 2009EL-2050 13690931 YP_006768058.1 CDS O3M_01895 NC_018650.1 387766 388254 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase YhhY complement(387766..388254) Escherichia coli O104:H4 str. 2009EL-2050 13690932 YP_006768059.1 CDS O3M_01900 NC_018650.1 388586 389623 D COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 388586..389623 Escherichia coli O104:H4 str. 2009EL-2050 13690933 YP_006768060.1 CDS O3M_01905 NC_018650.1 389746 390441 D COG1741 Pirin-related protein; protein yhhW 389746..390441 Escherichia coli O104:H4 str. 2009EL-2050 13690934 YP_006768061.1 CDS O3M_01910 NC_018650.1 390665 391660 D COG1609 Transcriptional regulators; gluconate operon transcriptional regulator 390665..391660 Escherichia coli O104:H4 str. 2009EL-2050 13690935 YP_006768062.1 CDS gntK NC_018650.1 391799 392326 D COG3265 Gluconate kinase; gluconate kinase 391799..392326 Escherichia coli O104:H4 str. 2009EL-2050 13690936 YP_006768063.1 CDS O3M_01920 NC_018650.1 392330 393670 D COG2610 H+/gluconate symporter and related permeases; low affinity gluconate transporter 392330..393670 Escherichia coli O104:H4 str. 2009EL-2050 13690937 YP_006768064.1 CDS O3M_01925 NC_018650.1 393727 394320 R COG2095 Multiple antibiotic transporter; antibiotic transporter complement(393727..394320) Escherichia coli O104:H4 str. 2009EL-2050 13690938 YP_006768065.1 CDS O3M_01930 NC_018650.1 394513 395616 D COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 394513..395616 Escherichia coli O104:H4 str. 2009EL-2050 13690939 YP_006768066.1 CDS O3M_01935 NC_018650.1 395889 398075 D COG0296 1,4-alpha-glucan branching enzyme; glycogen branching protein 395889..398075 Escherichia coli O104:H4 str. 2009EL-2050 13690940 YP_006768067.1 CDS O3M_01940 NC_018650.1 398072 400045 D COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen debranching protein 398072..400045 Escherichia coli O104:H4 str. 2009EL-2050 13690941 YP_006768068.1 CDS glgC NC_018650.1 400063 401358 D COG0448 ADP-glucose pyrophosphorylase; glucose-1-phosphate adenylyltransferase 400063..401358 Escherichia coli O104:H4 str. 2009EL-2050 13690942 YP_006768069.1 CDS glgA NC_018650.1 401358 402791 D COG0297 Glycogen synthase; glycogen synthase 401358..402791 Escherichia coli O104:H4 str. 2009EL-2050 13690943 YP_006768070.1 CDS O3M_01955 NC_018650.1 402810 405257 D COG0058 Glucan phosphorylase; glycogen phosphorylase 402810..405257 Escherichia coli O104:H4 str. 2009EL-2050 13690944 YP_006768071.1 CDS O3M_01960 NC_018650.1 405373 406890 D COG0226 ABC-type phosphate transport system, periplasmic component; phosphate transport system substrate-binding protein 405373..406890 Escherichia coli O104:H4 str. 2009EL-2050 13690945 YP_006768072.1 CDS O3M_01965 NC_018650.1 406906 407616 D hypothetical protein 406906..407616 Escherichia coli O104:H4 str. 2009EL-2050 13690946 YP_006768073.1 CDS O3M_01970 NC_018650.1 407619 408386 D hypothetical protein 407619..408386 Escherichia coli O104:H4 str. 2009EL-2050 13690947 YP_006768074.1 CDS O3M_01975 NC_018650.1 408389 408994 D hypothetical protein 408389..408994 Escherichia coli O104:H4 str. 2009EL-2050 13690948 YP_006768075.1 CDS glpD NC_018650.1 409046 410551 R COG0578 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase complement(409046..410551) Escherichia coli O104:H4 str. 2009EL-2050 13690949 YP_006768076.1 CDS glpE NC_018650.1 410741 411067 D COG0607 Rhodanese-related sulfurtransferase; thiosulfate sulfurtransferase 410741..411067 Escherichia coli O104:H4 str. 2009EL-2050 13690950 YP_006768077.1 CDS O3M_01990 NC_018650.1 411112 411942 D COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); intramembrane serine protease GlpG 411112..411942 Escherichia coli O104:H4 str. 2009EL-2050 13690951 YP_006768078.1 CDS O3M_01995 NC_018650.1 411959 412717 D COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor GlpR 411959..412717 Escherichia coli O104:H4 str. 2009EL-2050 13690952 YP_006768079.1 CDS O3M_02000 NC_018650.1 412699 414297 R COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain; sigma 54-dependent transcriptional regulator of rtcBA expression complement(412699..414297) Escherichia coli O104:H4 str. 2009EL-2050 13690953 YP_006768080.1 CDS O3M_02005 NC_018650.1 414486 415712 D COG1690 Uncharacterized conserved protein; hypothetical protein 414486..415712 Escherichia coli O104:H4 str. 2009EL-2050 13690954 YP_006768081.1 CDS O3M_02010 NC_018650.1 415716 416732 D COG0430 RNA 3'-terminal phosphate cyclase; RNA 3'-terminal-phosphate cyclase 415716..416732 Escherichia coli O104:H4 str. 2009EL-2050 13690955 YP_006768082.1 CDS O3M_02015 NC_018650.1 416775 419480 R COG2909 ATP-dependent transcriptional regulator; transcriptional regulator MalT complement(416775..419480) Escherichia coli O104:H4 str. 2009EL-2050 13690956 YP_006768083.1 CDS O3M_02020 NC_018650.1 420092 422485 D COG0058 Glucan phosphorylase; maltodextrin phosphorylase 420092..422485 Escherichia coli O104:H4 str. 2009EL-2050 13690957 YP_006768084.1 CDS malQ NC_018650.1 422495 424579 D COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 422495..424579 Escherichia coli O104:H4 str. 2009EL-2050 13690958 YP_006768085.1 CDS O3M_02030 NC_018650.1 424624 425940 R COG2610 H+/gluconate symporter and related permeases; high-affinity gluconate transporter complement(424624..425940) Escherichia coli O104:H4 str. 2009EL-2050 13690959 YP_006768086.1 CDS O3M_02035 NC_018650.1 426301 426876 R COG0316 Uncharacterized conserved protein; Fe/S biogenesis protein NfuA complement(426301..426876) Escherichia coli O104:H4 str. 2009EL-2050 13690960 YP_006768087.1 CDS O3M_02040 NC_018650.1 426935 427618 R COG1040 Predicted amidophosphoribosyltransferases; DNA utilization protein GntX complement(426935..427618) Escherichia coli O104:H4 str. 2009EL-2050 13690961 YP_006768088.1 CDS O3M_02045 NC_018650.1 427656 428426 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); carboxylesterase BioH 427656..428426 Escherichia coli O104:H4 str. 2009EL-2050 13690962 YP_006768089.1 CDS O3M_02050 NC_018650.1 428455 429333 R transposase complement(428455..429333) Escherichia coli O104:H4 str. 2009EL-2050 13690963 YP_006768090.1 CDS O3M_02055 NC_018650.1 429536 429772 R ferrous iron transport protein FeoC complement(429536..429772) Escherichia coli O104:H4 str. 2009EL-2050 13690964 YP_006768091.1 CDS feoB NC_018650.1 429772 432093 R COG0370 Fe2+ transport system protein B; ferrous iron transport protein B complement(429772..432093) Escherichia coli O104:H4 str. 2009EL-2050 13690965 YP_006768092.1 CDS feoA NC_018650.1 432110 432337 R COG1918 Fe2+ transport system protein A; ferrous iron transport protein A complement(432110..432337) Escherichia coli O104:H4 str. 2009EL-2050 13690966 YP_006768093.1 CDS O3M_02070 NC_018650.1 432775 435096 R COG2183 Transcriptional accessory protein; transcriptional accessory protein complement(432775..435096) Escherichia coli O104:H4 str. 2009EL-2050 13690967 YP_006768094.1 CDS greB NC_018650.1 435193 435669 R COG0782 Transcription elongation factor; transcription elongation factor GreB complement(435193..435669) Escherichia coli O104:H4 str. 2009EL-2050 13690968 YP_006768095.1 CDS ompR NC_018650.1 435897 436616 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; osmolarity response regulator 435897..436616 Escherichia coli O104:H4 str. 2009EL-2050 13690969 YP_006768096.1 CDS envZ NC_018650.1 436613 437965 D COG0642 Signal transduction histidine kinase; osmolarity sensor protein 436613..437965 Escherichia coli O104:H4 str. 2009EL-2050 13690970 YP_006768097.1 CDS O3M_02090 NC_018650.1 437995 438291 R COG2944 Predicted transcriptional regulator; HTH-type transcriptional regulator yiaG complement(437995..438291) Escherichia coli O104:H4 str. 2009EL-2050 13690971 YP_006768098.1 CDS O3M_02095 NC_018650.1 438350 438667 R COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; hypothetical protein complement(438350..438667) Escherichia coli O104:H4 str. 2009EL-2050 13690972 YP_006768099.1 CDS O3M_02100 NC_018650.1 438784 440406 R COG1866 Phosphoenolpyruvate carboxykinase (ATP); phosphoenolpyruvate carboxykinase complement(438784..440406) Escherichia coli O104:H4 str. 2009EL-2050 13690973 YP_006768100.1 CDS O3M_02105 NC_018650.1 440785 442509 D inner membrane protein 440785..442509 Escherichia coli O104:H4 str. 2009EL-2050 13690974 YP_006768101.1 CDS hslO NC_018650.1 442644 443522 R COG1281 Disulfide bond chaperones of the HSP33 family; Hsp33-like chaperonin complement(442644..443522) Escherichia coli O104:H4 str. 2009EL-2050 13690975 YP_006768102.1 CDS O3M_02115 NC_018650.1 443547 443948 R COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); ribosome-associated heat shock protein Hsp15 complement(443547..443948) Escherichia coli O104:H4 str. 2009EL-2050 13690976 YP_006768103.1 CDS O3M_02120 NC_018650.1 443959 444627 R COG1011 Predicted hydrolase (HAD superfamily); GMP/IMP nucleotidase complement(443959..444627) Escherichia coli O104:H4 str. 2009EL-2050 13690977 YP_006768104.1 CDS O3M_02125 NC_018650.1 444692 446827 R intracellular growth attenuator protein complement(444692..446827) Escherichia coli O104:H4 str. 2009EL-2050 13690978 YP_006768105.1 CDS nudE NC_018650.1 447147 447707 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; adenosine nucleotide hydrolase NudE 447147..447707 Escherichia coli O104:H4 str. 2009EL-2050 13690979 YP_006768106.1 CDS mrcA NC_018650.1 447875 450427 R COG5009 Membrane carboxypeptidase/penicillin-binding protein; penicillin-binding protein 1a complement(447875..450427) Escherichia coli O104:H4 str. 2009EL-2050 13690980 YP_006768107.1 CDS O3M_02140 NC_018650.1 450547 451326 D pilus assembly protein 450547..451326 Escherichia coli O104:H4 str. 2009EL-2050 13690981 YP_006768108.1 CDS O3M_02145 NC_018650.1 451326 451865 D fimbrial assembly protein 451326..451865 Escherichia coli O104:H4 str. 2009EL-2050 13690982 YP_006768109.1 CDS O3M_02150 NC_018650.1 451849 452289 D hypothetical protein 451849..452289 Escherichia coli O104:H4 str. 2009EL-2050 13690983 YP_006768110.1 CDS O3M_02155 NC_018650.1 452279 452683 D hypothetical protein 452279..452683 Escherichia coli O104:H4 str. 2009EL-2050 13690984 YP_006768111.1 CDS hofQ NC_018650.1 452595 453833 D COG4796 Type II secretory pathway, component HofQ; outer membrane porin HofQ 452595..453833 Escherichia coli O104:H4 str. 2009EL-2050 13690985 YP_006768112.1 CDS aroK NC_018650.1 454234 454755 D COG0703 Shikimate kinase; shikimate kinase I 454234..454755 Escherichia coli O104:H4 str. 2009EL-2050 13690986 YP_006768113.1 CDS aroB NC_018650.1 454812 455900 D COG0337 3-dehydroquinate synthetase; 3-dehydroquinate synthase 454812..455900 Escherichia coli O104:H4 str. 2009EL-2050 13690987 YP_006768114.1 CDS O3M_02175 NC_018650.1 455992 457278 D COG3266 Uncharacterized protein conserved in bacteria; cell division protein DamX 455992..457278 Escherichia coli O104:H4 str. 2009EL-2050 13690988 YP_006768115.1 CDS O3M_02180 NC_018650.1 457385 458221 D COG0338 Site-specific DNA methylase; DNA adenine methylase 457385..458221 Escherichia coli O104:H4 str. 2009EL-2050 13690989 YP_006768116.1 CDS O3M_02185 NC_018650.1 458239 458916 D COG0036 Pentose-5-phosphate-3-epimerase; ribulose-phosphate 3-epimerase 458239..458916 Escherichia coli O104:H4 str. 2009EL-2050 13690990 YP_006768117.1 CDS O3M_02190 NC_018650.1 458909 459667 D COG0546 Predicted phosphatases; phosphoglycolate phosphatase 458909..459667 Escherichia coli O104:H4 str. 2009EL-2050 13690991 YP_006768118.1 CDS O3M_02195 NC_018650.1 459660 460664 D COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 459660..460664 Escherichia coli O104:H4 str. 2009EL-2050 13690992 YP_006768119.1 CDS O3M_02200 NC_018650.1 460933 461838 D hypothetical protein 460933..461838 Escherichia coli O104:H4 str. 2009EL-2050 13690993 YP_006768120.1 CDS O3M_02205 NC_018650.1 461855 462217 D hypothetical protein 461855..462217 Escherichia coli O104:H4 str. 2009EL-2050 13690994 YP_006768121.1 CDS O3M_02210 NC_018650.1 462301 463464 D COG3457 Predicted amino acid racemase; amino acid racemase 462301..463464 Escherichia coli O104:H4 str. 2009EL-2050 13690995 YP_006768122.1 CDS O3M_02215 NC_018650.1 463464 464690 D COG1015 Phosphopentomutase; mutase 463464..464690 Escherichia coli O104:H4 str. 2009EL-2050 13690996 YP_006768123.1 CDS O3M_02220 NC_018650.1 464687 465565 D COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold; hydrolase 464687..465565 Escherichia coli O104:H4 str. 2009EL-2050 13690997 YP_006768124.1 CDS O3M_02225 NC_018650.1 465576 465929 D COG0698 Ribose 5-phosphate isomerase RpiB; hypothetical protein 465576..465929 Escherichia coli O104:H4 str. 2009EL-2050 13690998 YP_006768125.1 CDS O3M_02230 NC_018650.1 465941 467245 D inner membrane protein 465941..467245 Escherichia coli O104:H4 str. 2009EL-2050 13690999 YP_006768126.1 CDS O3M_02235 NC_018650.1 467257 468342 D hypothetical protein 467257..468342 Escherichia coli O104:H4 str. 2009EL-2050 13691000 YP_006768127.1 CDS O3M_02240 NC_018650.1 468494 469225 R COG2188 Transcriptional regulators; DNA-binding transcriptional regulator FrlR complement(468494..469225) Escherichia coli O104:H4 str. 2009EL-2050 13691001 YP_006768128.1 CDS O3M_02245 NC_018650.1 469325 470110 R COG0524 Sugar kinases, ribokinase family; fructoselysine 6-kinase complement(469325..470110) Escherichia coli O104:H4 str. 2009EL-2050 13691002 YP_006768129.1 CDS O3M_02250 NC_018650.1 470107 470937 R COG1082 Sugar phosphate isomerases/epimerases; fructoselysine 3-epimerase complement(470107..470937) Escherichia coli O104:H4 str. 2009EL-2050 13691003 YP_006768130.1 CDS frlB NC_018650.1 470987 472009 R COG2222 Predicted phosphosugar isomerases; fructoselysine-6-P-deglycase complement(470987..472009) Escherichia coli O104:H4 str. 2009EL-2050 13691004 YP_006768131.1 CDS frlA NC_018650.1 472030 473367 R COG0531 Amino acid transporters; fructoselysine transporter complement(472030..473367) Escherichia coli O104:H4 str. 2009EL-2050 13691005 YP_006768132.1 CDS O3M_02265 NC_018650.1 473662 473829 R lipoprotein complement(473662..473829) Escherichia coli O104:H4 str. 2009EL-2050 13691006 YP_006768133.1 CDS cysG NC_018650.1 474076 475449 R COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); siroheme synthase complement(474076..475449) Escherichia coli O104:H4 str. 2009EL-2050 13691007 YP_006768134.1 CDS O3M_02275 NC_018650.1 475468 476274 R COG2116 Formate/nitrite family of transporters; nitrite transporter NirC complement(475468..476274) Escherichia coli O104:H4 str. 2009EL-2050 13691008 YP_006768135.1 CDS nirD NC_018650.1 476401 476727 R COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; nitrite reductase small subunit complement(476401..476727) Escherichia coli O104:H4 str. 2009EL-2050 13691009 YP_006768136.1 CDS O3M_02285 NC_018650.1 476724 479267 R COG1251 NAD(P)H-nitrite reductase; nitrite reductase subunit NirD complement(476724..479267) Escherichia coli O104:H4 str. 2009EL-2050 13691010 YP_006768137.1 CDS O3M_02290 NC_018650.1 479529 480710 R COG0477 Permeases of the major facilitator superfamily; transporter complement(479529..480710) Escherichia coli O104:H4 str. 2009EL-2050 13691011 YP_006768138.1 CDS O3M_02295 NC_018650.1 480981 481553 D COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase A 480981..481553 Escherichia coli O104:H4 str. 2009EL-2050 13691012 YP_006768139.1 CDS O3M_02300 NC_018650.1 481658 481825 D hypothetical protein 481658..481825 Escherichia coli O104:H4 str. 2009EL-2050 13691013 YP_006768140.1 CDS O3M_02305 NC_018650.1 481815 482417 D COG2184 Protein involved in cell division; cell filamentation protein Fic 481815..482417 Escherichia coli O104:H4 str. 2009EL-2050 13691014 YP_006768141.1 CDS O3M_02310 NC_018650.1 482449 483012 D COG0512 Anthranilate/para-aminobenzoate synthases component II; para-aminobenzoate synthase component II 482449..483012 Escherichia coli O104:H4 str. 2009EL-2050 13691015 YP_006768142.1 CDS argD NC_018650.1 483098 484318 D COG4992 Ornithine/acetylornithine aminotransferase; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 483098..484318 Escherichia coli O104:H4 str. 2009EL-2050 13691016 YP_006768143.1 CDS O3M_02320 NC_018650.1 484385 486475 R COG1289 Predicted membrane protein; hypothetical protein complement(484385..486475) Escherichia coli O104:H4 str. 2009EL-2050 13691017 YP_006768144.1 CDS O3M_02325 NC_018650.1 486526 487158 R COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; DNA-binding transcriptional dual regulator Crp complement(486526..487158) Escherichia coli O104:H4 str. 2009EL-2050 13691018 YP_006768145.1 CDS O3M_02330 NC_018650.1 487460 487864 D COG1765 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 487460..487864 Escherichia coli O104:H4 str. 2009EL-2050 13691019 YP_006768146.1 CDS O3M_02335 NC_018650.1 487919 488788 R COG3954 Phosphoribulokinase; phosphoribulokinase complement(487919..488788) Escherichia coli O104:H4 str. 2009EL-2050 13691020 YP_006768147.1 CDS O3M_02340 NC_018650.1 488842 489060 R COG3089 Uncharacterized protein conserved in bacteria; hypothetical protein complement(488842..489060) Escherichia coli O104:H4 str. 2009EL-2050 13691021 YP_006768148.1 CDS O3M_02345 NC_018650.1 489054 490076 R COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold; hydrolase complement(489054..490076) Escherichia coli O104:H4 str. 2009EL-2050 13691022 YP_006768149.1 CDS O3M_02350 NC_018650.1 490076 491989 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein complement(490076..491989) Escherichia coli O104:H4 str. 2009EL-2050 13691023 YP_006768150.1 CDS O3M_02355 NC_018650.1 492120 492671 D COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); glutathione-regulated potassium-efflux system ancillary protein KefG 492120..492671 Escherichia coli O104:H4 str. 2009EL-2050 13691024 YP_006768151.1 CDS O3M_02360 NC_018650.1 492671 494476 D COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefB 492671..494476 Escherichia coli O104:H4 str. 2009EL-2050 13691025 YP_006768152.1 CDS O3M_02365 NC_018650.1 494486 494686 D COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain; hypothetical protein 494486..494686 Escherichia coli O104:H4 str. 2009EL-2050 13691026 YP_006768153.1 CDS O3M_02370 NC_018650.1 494781 495371 D COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; FKBP-type peptidyl-prolyl cis-trans isomerase 494781..495371 Escherichia coli O104:H4 str. 2009EL-2050 13691027 YP_006768154.1 CDS O3M_02375 NC_018650.1 495420 495638 R COG2900 Uncharacterized protein conserved in bacteria; phi X174 lysis protein complement(495420..495638) Escherichia coli O104:H4 str. 2009EL-2050 13691028 YP_006768155.1 CDS O3M_02380 NC_018650.1 495859 496671 D COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; FKBP-type peptidyl-prolyl cis-trans isomerase 495859..496671 Escherichia coli O104:H4 str. 2009EL-2050 13691029 YP_006768156.1 CDS O3M_02385 NC_018650.1 496838 497560 D COG2964 Uncharacterized protein conserved in bacteria; DNA-binding transcriptional regulator 496838..497560 Escherichia coli O104:H4 str. 2009EL-2050 13691030 YP_006768157.1 CDS O3M_02390 NC_018650.1 497560 497946 D COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction; sulfur transfer complex subunit TusD 497560..497946 Escherichia coli O104:H4 str. 2009EL-2050 13691031 YP_006768158.1 CDS O3M_02395 NC_018650.1 497946 498305 D COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur; sulfur relay protein TusC 497946..498305 Escherichia coli O104:H4 str. 2009EL-2050 13691032 YP_006768159.1 CDS O3M_02400 NC_018650.1 498313 498600 D COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur; sulfur transfer complex subunit TusB 498313..498600 Escherichia coli O104:H4 str. 2009EL-2050 13691033 YP_006768160.1 CDS rpsL NC_018650.1 498726 499100 D COG0048 Ribosomal protein S12; 30S ribosomal protein S12 498726..499100 Escherichia coli O104:H4 str. 2009EL-2050 13691034 YP_006768161.1 CDS O3M_02410 NC_018650.1 499197 499667 D COG0049 Ribosomal protein S7; 30S ribosomal protein S7 499197..499667 Escherichia coli O104:H4 str. 2009EL-2050 13691035 YP_006768162.1 CDS O3M_02415 NC_018650.1 499764 501878 D COG0480 Translation elongation factors (GTPases); elongation factor G 499764..501878 Escherichia coli O104:H4 str. 2009EL-2050 13691036 YP_006768163.1 CDS O3M_02420 NC_018650.1 501949 503133 D COG0050 GTPases - translation elongation factors; elongation factor Tu 501949..503133 Escherichia coli O104:H4 str. 2009EL-2050 13691037 YP_006768164.1 CDS O3M_02425 NC_018650.1 503316 503510 D COG2906 Bacterioferritin-associated ferredoxin; bacterioferritin-associated ferredoxin 503316..503510 Escherichia coli O104:H4 str. 2009EL-2050 13691038 YP_006768165.1 CDS O3M_02430 NC_018650.1 503583 504059 D COG2193 Bacterioferritin (cytochrome b1); bacterioferritin 503583..504059 Escherichia coli O104:H4 str. 2009EL-2050 13691039 YP_006768166.1 CDS O3M_02435 NC_018650.1 504056 504523 R leader peptidase; methyl transferase (General Secretory Pathway); COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; bifunctional prepilin peptidase HopD complement(504056..504523) Escherichia coli O104:H4 str. 2009EL-2050 13691040 YP_006768167.1 CDS rpsJ NC_018650.1 504902 505213 D COG0051 Ribosomal protein S10; 30S ribosomal protein S10 504902..505213 Escherichia coli O104:H4 str. 2009EL-2050 13691041 YP_006768168.1 CDS rplC NC_018650.1 505246 505875 D COG0087 Ribosomal protein L3; 50S ribosomal protein L3 505246..505875 Escherichia coli O104:H4 str. 2009EL-2050 13691042 YP_006768169.1 CDS rplD NC_018650.1 505886 506491 D COG0088 Ribosomal protein L4; 50S ribosomal protein L4 505886..506491 Escherichia coli O104:H4 str. 2009EL-2050 13691043 YP_006768170.1 CDS rplW NC_018650.1 506488 506790 D COG0089 Ribosomal protein L23; 50S ribosomal protein L23 506488..506790 Escherichia coli O104:H4 str. 2009EL-2050 13691044 YP_006768171.1 CDS rplB NC_018650.1 506808 507629 D COG0090 Ribosomal protein L2; 50S ribosomal protein L2 506808..507629 Escherichia coli O104:H4 str. 2009EL-2050 13691045 YP_006768172.1 CDS rpsS NC_018650.1 507646 507924 D COG0185 Ribosomal protein S19; 30S ribosomal protein S19 507646..507924 Escherichia coli O104:H4 str. 2009EL-2050 13691046 YP_006768173.1 CDS rplV NC_018650.1 507939 508271 D COG0091 Ribosomal protein L22; 50S ribosomal protein L22 507939..508271 Escherichia coli O104:H4 str. 2009EL-2050 13691047 YP_006768174.1 CDS rpsC NC_018650.1 508289 508990 D COG0092 Ribosomal protein S3; 30S ribosomal protein S3 508289..508990 Escherichia coli O104:H4 str. 2009EL-2050 13691048 YP_006768175.1 CDS rplP NC_018650.1 509003 509413 D COG0197 Ribosomal protein L16/L10E; 50S ribosomal protein L16 509003..509413 Escherichia coli O104:H4 str. 2009EL-2050 13691049 YP_006768176.1 CDS O3M_02485 NC_018650.1 509413 509604 D COG0255 Ribosomal protein L29; 50S ribosomal protein L29 509413..509604 Escherichia coli O104:H4 str. 2009EL-2050 13691050 YP_006768177.1 CDS rpsQ NC_018650.1 509604 509858 D COG0186 Ribosomal protein S17; 30S ribosomal protein S17 509604..509858 Escherichia coli O104:H4 str. 2009EL-2050 13691051 YP_006768178.1 CDS rplN NC_018650.1 510023 510394 D COG0093 Ribosomal protein L14; 50S ribosomal protein L14 510023..510394 Escherichia coli O104:H4 str. 2009EL-2050 13691052 YP_006768179.1 CDS rplX NC_018650.1 510405 510719 D COG0198 Ribosomal protein L24; 50S ribosomal protein L24 510405..510719 Escherichia coli O104:H4 str. 2009EL-2050 13691053 YP_006768180.1 CDS rplE NC_018650.1 510734 511273 D COG0094 Ribosomal protein L5; 50S ribosomal protein L5 510734..511273 Escherichia coli O104:H4 str. 2009EL-2050 13691054 YP_006768181.1 CDS rpsN NC_018650.1 511288 511593 D COG0199 Ribosomal protein S14; 30S ribosomal protein S14 511288..511593 Escherichia coli O104:H4 str. 2009EL-2050 13691055 YP_006768182.1 CDS rpsH NC_018650.1 511627 512019 D COG0096 Ribosomal protein S8; 30S ribosomal protein S8 511627..512019 Escherichia coli O104:H4 str. 2009EL-2050 13691056 YP_006768183.1 CDS rplF NC_018650.1 512032 512565 D COG0097 Ribosomal protein L6P/L9E; 50S ribosomal protein L6 512032..512565 Escherichia coli O104:H4 str. 2009EL-2050 13691057 YP_006768184.1 CDS rplR NC_018650.1 512575 512928 D COG0256 Ribosomal protein L18; 50S ribosomal protein L18 512575..512928 Escherichia coli O104:H4 str. 2009EL-2050 13691058 YP_006768185.1 CDS rpsE NC_018650.1 512943 513446 D COG0098 Ribosomal protein S5; 30S ribosomal protein S5 512943..513446 Escherichia coli O104:H4 str. 2009EL-2050 13691059 YP_006768186.1 CDS rpmD NC_018650.1 513450 513629 D COG1841 Ribosomal protein L30/L7E; 50S ribosomal protein L30 513450..513629 Escherichia coli O104:H4 str. 2009EL-2050 13691060 YP_006768187.1 CDS rplO NC_018650.1 513633 514067 D COG0200 Ribosomal protein L15; 50S ribosomal protein L15 513633..514067 Escherichia coli O104:H4 str. 2009EL-2050 13691061 YP_006768188.1 CDS secY NC_018650.1 514075 515406 D COG0201 Preprotein translocase subunit SecY; preprotein translocase subunit SecY 514075..515406 Escherichia coli O104:H4 str. 2009EL-2050 13691062 YP_006768189.1 CDS rpmJ NC_018650.1 515438 515554 D COG0257 Ribosomal protein L36; 50S ribosomal protein L36 515438..515554 Escherichia coli O104:H4 str. 2009EL-2050 13691063 YP_006768190.1 CDS rpsM NC_018650.1 515701 516057 D COG0099 Ribosomal protein S13; 30S ribosomal protein S13 515701..516057 Escherichia coli O104:H4 str. 2009EL-2050 13691064 YP_006768191.1 CDS O3M_02560 NC_018650.1 516074 516463 D COG0100 Ribosomal protein S11; 30S ribosomal protein S11 516074..516463 Escherichia coli O104:H4 str. 2009EL-2050 13691065 YP_006768192.1 CDS rpsD NC_018650.1 516497 517117 D COG0522 Ribosomal protein S4 and related proteins; 30S ribosomal protein S4 516497..517117 Escherichia coli O104:H4 str. 2009EL-2050 13691066 YP_006768193.1 CDS O3M_02570 NC_018650.1 517143 518132 D COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-directed RNA polymerase subunit alpha 517143..518132 Escherichia coli O104:H4 str. 2009EL-2050 13691067 YP_006768194.1 CDS rplQ NC_018650.1 518173 518556 D COG0203 Ribosomal protein L17; 50S ribosomal protein L17 518173..518556 Escherichia coli O104:H4 str. 2009EL-2050 13691068 YP_006768195.1 CDS O3M_02580 NC_018650.1 518663 519031 D hypothetical protein 518663..519031 Escherichia coli O104:H4 str. 2009EL-2050 13691069 YP_006768196.1 CDS zntR NC_018650.1 519042 519467 D COG0789 Predicted transcriptional regulators; zinc-responsive transcriptional regulator 519042..519467 Escherichia coli O104:H4 str. 2009EL-2050 13691070 YP_006768197.1 CDS O3M_02590 NC_018650.1 519523 519741 D COG3036 Uncharacterized protein conserved in bacteria; hypothetical protein 519523..519741 Escherichia coli O104:H4 str. 2009EL-2050 13691071 YP_006768198.1 CDS mscL NC_018650.1 519738 520148 R COG1970 Large-conductance mechanosensitive channel; large conductance mechanosensitive channel protein complement(519738..520148) Escherichia coli O104:H4 str. 2009EL-2050 13691072 YP_006768199.1 CDS trkA NC_018650.1 520278 521654 R COG0569 K+ transport systems, NAD-binding component; potassium transporter peripheral membrane protein complement(520278..521654) Escherichia coli O104:H4 str. 2009EL-2050 13691073 YP_006768200.1 CDS O3M_02605 NC_018650.1 521676 522965 R COG0144 tRNA and rRNA cytosine-C5-methylases; 16S rRNA methyltransferase B complement(521676..522965) Escherichia coli O104:H4 str. 2009EL-2050 13691074 YP_006768201.1 CDS fmt NC_018650.1 523011 523958 R COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase complement(523011..523958) Escherichia coli O104:H4 str. 2009EL-2050 13691075 YP_006768202.1 CDS def NC_018650.1 523973 524482 R COG0242 N-formylmethionyl-tRNA deformylase; peptide deformylase complement(523973..524482) Escherichia coli O104:H4 str. 2009EL-2050 13691076 YP_006768203.1 CDS O3M_02620 NC_018650.1 524612 525736 D COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 524612..525736 Escherichia coli O104:H4 str. 2009EL-2050 13691077 YP_006768204.1 CDS O3M_02625 NC_018650.1 525708 526181 D COG2922 Uncharacterized protein conserved in bacteria; hypothetical protein 525708..526181 Escherichia coli O104:H4 str. 2009EL-2050 13691078 YP_006768205.1 CDS O3M_02630 NC_018650.1 526210 526752 D COG0551 Zn-finger domain associated with topoisomerase type I; DNA topoisomerase 526210..526752 Escherichia coli O104:H4 str. 2009EL-2050 13691079 YP_006768206.1 CDS O3M_02635 NC_018650.1 526757 527329 D COG0009 Putative translation factor (SUA5); tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein 526757..527329 Escherichia coli O104:H4 str. 2009EL-2050 13691080 YP_006768207.1 CDS aroE NC_018650.1 527334 528152 D COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 527334..528152 Escherichia coli O104:H4 str. 2009EL-2050 13691081 YP_006768208.1 CDS O3M_02645 NC_018650.1 528149 528406 D hypothetical protein 528149..528406 Escherichia coli O104:H4 str. 2009EL-2050 13691082 YP_006768209.1 CDS O3M_02650 NC_018650.1 528382 528936 R COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; hypothetical protein complement(528382..528936) Escherichia coli O104:H4 str. 2009EL-2050 13691083 YP_006768210.1 CDS O3M_02655 NC_018650.1 534988 535746 R COG1126 ABC-type polar amino acid transport system, ATPase component; phosphate ABC transporter ATP-binding protein complement(534988..535746) Escherichia coli O104:H4 str. 2009EL-2050 13691091 YP_006768211.1 CDS O3M_02660 NC_018650.1 535754 536857 R COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(535754..536857) Escherichia coli O104:H4 str. 2009EL-2050 13691092 YP_006768212.1 CDS O3M_02665 NC_018650.1 536867 538048 R COG4597 ABC-type amino acid transport system, permease component; transport system permease complement(536867..538048) Escherichia coli O104:H4 str. 2009EL-2050 13691093 YP_006768213.1 CDS O3M_02670 NC_018650.1 538116 539141 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein complement(538116..539141) Escherichia coli O104:H4 str. 2009EL-2050 13691094 YP_006768214.1 CDS O3M_02675 NC_018650.1 539572 539793 R hypothetical protein complement(539572..539793) Escherichia coli O104:H4 str. 2009EL-2050 13691095 YP_006768215.1 CDS O3M_02680 NC_018650.1 540046 543150 R COG0841 Cation/multidrug efflux pump; acriflavine resistance protein complement(540046..543150) Escherichia coli O104:H4 str. 2009EL-2050 13691096 YP_006768216.1 CDS O3M_02685 NC_018650.1 543162 544319 R COG0845 Membrane-fusion protein; hypothetical protein complement(543162..544319) Escherichia coli O104:H4 str. 2009EL-2050 13691097 YP_006768217.1 CDS O3M_02690 NC_018650.1 544718 545380 D COG1309 Transcriptional regulator; DNA-binding transcriptional regulator EnvR 544718..545380 Escherichia coli O104:H4 str. 2009EL-2050 13691098 YP_006768218.1 CDS O3M_02695 NC_018650.1 545383 545562 R hypothetical protein complement(545383..545562) Escherichia coli O104:H4 str. 2009EL-2050 13691099 YP_006768219.1 CDS O3M_02700 NC_018650.1 545646 546530 R COG0863 DNA modification methylase; methyltransferase complement(545646..546530) Escherichia coli O104:H4 str. 2009EL-2050 13691100 YP_006768220.1 CDS fis NC_018650.1 546616 546912 R COG2901 Factor for inversion stimulation Fis, transcriptional activator; global DNA-binding transcriptional dual regulator Fis complement(546616..546912) Escherichia coli O104:H4 str. 2009EL-2050 13691101 YP_006768221.1 CDS O3M_02710 NC_018650.1 546938 547903 R COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase B complement(546938..547903) Escherichia coli O104:H4 str. 2009EL-2050 13691102 YP_006768222.1 CDS prmA NC_018650.1 548232 549113 R COG2264 Ribosomal protein L11 methylase; 50S ribosomal protein L11 methyltransferase complement(548232..549113) Escherichia coli O104:H4 str. 2009EL-2050 13691103 YP_006768223.1 CDS panF NC_018650.1 549125 550576 R COG4145 Na+/panthothenate symporter; sodium/panthothenate symporter complement(549125..550576) Escherichia coli O104:H4 str. 2009EL-2050 13691104 YP_006768224.1 CDS O3M_02725 NC_018650.1 550566 550808 R COG3924 Predicted membrane protein; hypothetical protein complement(550566..550808) Escherichia coli O104:H4 str. 2009EL-2050 13691105 YP_006768225.1 CDS O3M_02730 NC_018650.1 550917 552266 R COG0439 Biotin carboxylase; acetyl-CoA carboxylase biotin carboxylase subunit complement(550917..552266) Escherichia coli O104:H4 str. 2009EL-2050 13691106 YP_006768226.1 CDS O3M_02735 NC_018650.1 552277 552747 R COG0511 Biotin carboxyl carrier protein; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(552277..552747) Escherichia coli O104:H4 str. 2009EL-2050 13691107 YP_006768227.1 CDS O3M_02740 NC_018650.1 553152 553316 R COG2717 Predicted membrane protein; hypothetical protein complement(553152..553316) Escherichia coli O104:H4 str. 2009EL-2050 13691108 YP_006768228.1 CDS O3M_02745 NC_018650.1 553725 554699 R COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; quinone oxidoreductase complement(553725..554699) Escherichia coli O104:H4 str. 2009EL-2050 13691109 YP_006768229.1 CDS O3M_02750 NC_018650.1 554851 556791 D COG2199 FOG: GGDEF domain; regulatory protein CsrD 554851..556791 Escherichia coli O104:H4 str. 2009EL-2050 13691110 YP_006768230.1 CDS O3M_02755 NC_018650.1 557096 558139 D COG1077 Actin-like ATPase involved in cell morphogenesis; rod shape-determining protein MreB 557096..558139 Escherichia coli O104:H4 str. 2009EL-2050 13691111 YP_006768231.1 CDS O3M_02760 NC_018650.1 558205 559308 D COG1792 Cell shape-determining protein; rod shape-determining protein MreC 558205..559308 Escherichia coli O104:H4 str. 2009EL-2050 13691112 YP_006768232.1 CDS O3M_02765 NC_018650.1 559193 559324 D hypothetical protein 559193..559324 Escherichia coli O104:H4 str. 2009EL-2050 13691113 YP_006768233.1 CDS O3M_02770 NC_018650.1 559308 559796 D COG2891 Cell shape-determining protein; rod shape-determining protein MreD 559308..559796 Escherichia coli O104:H4 str. 2009EL-2050 13691114 YP_006768234.1 CDS O3M_02775 NC_018650.1 559805 560398 D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; maf-like protein 559805..560398 Escherichia coli O104:H4 str. 2009EL-2050 13691115 YP_006768235.1 CDS O3M_02780 NC_018650.1 560388 561857 D COG1530 Ribonucleases G and E; ribonuclease G 560388..561857 Escherichia coli O104:H4 str. 2009EL-2050 13691116 YP_006768236.1 CDS O3M_02785 NC_018650.1 561925 565725 D COG3164 Predicted membrane protein; hypothetical protein 561925..565725 Escherichia coli O104:H4 str. 2009EL-2050 13691117 YP_006768237.1 CDS tldD NC_018650.1 565881 567326 D COG0312 Predicted Zn-dependent proteases and their inactivated homologs; protease TldD 565881..567326 Escherichia coli O104:H4 str. 2009EL-2050 13691118 YP_006768238.1 CDS O3M_02795 NC_018650.1 567454 568383 R COG0583 Transcriptional regulator; transcriptional regulator complement(567454..568383) Escherichia coli O104:H4 str. 2009EL-2050 13691119 YP_006768239.1 CDS O3M_02800 NC_018650.1 568566 568769 D efflux system membrane protein 568566..568769 Escherichia coli O104:H4 str. 2009EL-2050 13691120 YP_006768240.1 CDS O3M_02805 NC_018650.1 568777 569709 D COG1566 Multidrug resistance efflux pump; p-hydroxybenzoic acid efflux subunit AaeA 568777..569709 Escherichia coli O104:H4 str. 2009EL-2050 13691121 YP_006768241.1 CDS O3M_02810 NC_018650.1 569715 571682 D COG1289 Predicted membrane protein; p-hydroxybenzoic acid efflux subunit AaeB 569715..571682 Escherichia coli O104:H4 str. 2009EL-2050 13691122 YP_006768242.1 CDS O3M_02815 NC_018650.1 571774 572046 D COG2732 Barstar, RNAse (barnase) inhibitor; barnase inhibitor 571774..572046 Escherichia coli O104:H4 str. 2009EL-2050 13691123 YP_006768243.1 CDS O3M_02820 NC_018650.1 572102 572365 R hypothetical protein complement(572102..572365) Escherichia coli O104:H4 str. 2009EL-2050 13691124 YP_006768244.1 CDS O3M_02825 NC_018650.1 572730 573200 R COG1438 Arginine repressor; arginine repressor complement(572730..573200) Escherichia coli O104:H4 str. 2009EL-2050 13691125 YP_006768245.1 CDS O3M_02830 NC_018650.1 573635 574573 D COG0039 Malate/lactate dehydrogenases; malate dehydrogenase 573635..574573 Escherichia coli O104:H4 str. 2009EL-2050 13691126 YP_006768246.1 CDS O3M_02835 NC_018650.1 574636 575703 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease complement(574636..575703) Escherichia coli O104:H4 str. 2009EL-2050 13691127 YP_006768247.1 CDS O3M_02840 NC_018650.1 575793 577160 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease complement(575793..577160) Escherichia coli O104:H4 str. 2009EL-2050 13691128 YP_006768248.1 CDS O3M_02845 NC_018650.1 577314 577712 R COG3105 Uncharacterized protein conserved in bacteria; hypothetical protein complement(577314..577712) Escherichia coli O104:H4 str. 2009EL-2050 13691129 YP_006768249.1 CDS O3M_02850 NC_018650.1 577906 579033 D COG1485 Predicted ATPase; nucleoside triphosphate hydrolase domain-containing protein 577906..579033 Escherichia coli O104:H4 str. 2009EL-2050 13691130 YP_006768250.1 CDS rplM NC_018650.1 579252 579680 D COG0102 Ribosomal protein L13; 50S ribosomal protein L13 579252..579680 Escherichia coli O104:H4 str. 2009EL-2050 13691131 YP_006768251.1 CDS rpsI NC_018650.1 579696 580088 D COG0103 Ribosomal protein S9; 30S ribosomal protein S9 579696..580088 Escherichia coli O104:H4 str. 2009EL-2050 13691132 YP_006768252.1 CDS sspA NC_018650.1 580483 581121 D COG0625 Glutathione S-transferase; stringent starvation protein A 580483..581121 Escherichia coli O104:H4 str. 2009EL-2050 13691133 YP_006768253.1 CDS O3M_02870 NC_018650.1 581127 581624 D COG2969 Stringent starvation protein B; ClpXP protease specificity-enhancing factor 581127..581624 Escherichia coli O104:H4 str. 2009EL-2050 13691134 YP_006768254.1 CDS O3M_02875 NC_018650.1 581667 583034 R COG3069 C4-dicarboxylate transporter; cryptic C4-dicarboxylate transporter DcuD complement(581667..583034) Escherichia coli O104:H4 str. 2009EL-2050 13691135 YP_006768255.1 CDS O3M_02880 NC_018650.1 583414 584205 D COG2186 Transcriptional regulators; transcriptional regulator NanR 583414..584205 Escherichia coli O104:H4 str. 2009EL-2050 13691136 YP_006768256.1 CDS O3M_02885 NC_018650.1 584327 585220 D COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; N-acetylneuraminate lyase 584327..585220 Escherichia coli O104:H4 str. 2009EL-2050 13691137 YP_006768257.1 CDS O3M_02890 NC_018650.1 585329 586819 D COG0477 Permeases of the major facilitator superfamily; sialic acid transporter 585329..586819 Escherichia coli O104:H4 str. 2009EL-2050 13691138 YP_006768258.1 CDS O3M_02895 NC_018650.1 586867 587556 D COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; N-acetylmannosamine-6-phosphate 2-epimerase 586867..587556 Escherichia coli O104:H4 str. 2009EL-2050 13691139 YP_006768259.1 CDS O3M_02900 NC_018650.1 587553 588428 D COG1940 Transcriptional regulator/sugar kinase; N-acetylmannosamine kinase 587553..588428 Escherichia coli O104:H4 str. 2009EL-2050 13691140 YP_006768260.1 CDS O3M_02905 NC_018650.1 588425 588889 D COG2731 Beta-galactosidase, beta subunit; hypothetical protein 588425..588889 Escherichia coli O104:H4 str. 2009EL-2050 13691141 YP_006768261.1 CDS O3M_02910 NC_018650.1 588965 589270 R IS600 orf complement(588965..589270) Escherichia coli O104:H4 str. 2009EL-2050 13691142 YP_006768262.1 CDS O3M_02915 NC_018650.1 589287 589766 R COG4804 Uncharacterized conserved protein; hypothetical protein complement(589287..589766) Escherichia coli O104:H4 str. 2009EL-2050 13691143 YP_006768263.1 CDS gltD NC_018650.1 589950 591368 R COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; glutamate synthase subunit beta complement(589950..591368) Escherichia coli O104:H4 str. 2009EL-2050 13691144 YP_006768264.1 CDS gltB NC_018650.1 591381 595841 R COG0067 Glutamate synthase domain 1; glutamate synthase subunit alpha complement(591381..595841) Escherichia coli O104:H4 str. 2009EL-2050 13691145 YP_006768265.1 CDS O3M_02930 NC_018650.1 596516 597445 D COG1242 Predicted Fe-S oxidoreductase; Fe-S oxidoreductase 596516..597445 Escherichia coli O104:H4 str. 2009EL-2050 13691146 YP_006768266.1 CDS O3M_02935 NC_018650.1 597541 599877 D COG0642 Signal transduction histidine kinase; aerobic respiration control sensor protein ArcB 597541..599877 Escherichia coli O104:H4 str. 2009EL-2050 13691147 YP_006768267.1 CDS O3M_02940 NC_018650.1 600107 600760 D COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis; isoprenoid biosynthesis protein 600107..600760 Escherichia coli O104:H4 str. 2009EL-2050 13691148 YP_006768268.1 CDS mtgA NC_018650.1 600757 601485 D COG0744 Membrane carboxypeptidase (penicillin-binding protein); monofunctional biosynthetic peptidoglycan transglycosylase 600757..601485 Escherichia coli O104:H4 str. 2009EL-2050 13691149 YP_006768269.1 CDS O3M_02950 NC_018650.1 601482 602114 R hypothetical protein complement(601482..602114) Escherichia coli O104:H4 str. 2009EL-2050 13691150 YP_006768270.1 CDS O3M_02955 NC_018650.1 602327 602599 R COG1925 Phosphotransferase system, HPr-related proteins; PTS system phosphohistidinoprotein-hexose phosphotransferase Npr complement(602327..602599) Escherichia coli O104:H4 str. 2009EL-2050 13691151 YP_006768271.1 CDS O3M_02960 NC_018650.1 602596 603450 R COG1660 Predicted P-loop-containing kinase; glmZ(sRNA)-inactivating NTPase complement(602596..603450) Escherichia coli O104:H4 str. 2009EL-2050 13691152 YP_006768272.1 CDS O3M_02965 NC_018650.1 603496 603987 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system sugar transporter subunit IIA complement(603496..603987) Escherichia coli O104:H4 str. 2009EL-2050 13691153 YP_006768273.1 CDS O3M_02970 NC_018650.1 604105 604392 R COG1544 Ribosome-associated protein Y (PSrp-1); ribosome hibernation promoting factor HPF complement(604105..604392) Escherichia coli O104:H4 str. 2009EL-2050 13691154 YP_006768274.1 CDS O3M_02975 NC_018650.1 604415 605848 R COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; RNA polymerase factor sigma-54 complement(604415..605848) Escherichia coli O104:H4 str. 2009EL-2050 13691155 YP_006768275.1 CDS O3M_02980 NC_018650.1 605896 606621 R COG1137 ABC-type (unclassified) transport system, ATPase component; lipopolysaccharide ABC transporter ATP-binding protein complement(605896..606621) Escherichia coli O104:H4 str. 2009EL-2050 13691156 YP_006768276.1 CDS O3M_02985 NC_018650.1 606628 607185 R COG1934 Uncharacterized protein conserved in bacteria; lipopolysaccharide transport periplasmic protein LptA complement(606628..607185) Escherichia coli O104:H4 str. 2009EL-2050 13691157 YP_006768277.1 CDS O3M_02990 NC_018650.1 607154 607729 R COG3117 Uncharacterized protein conserved in bacteria; lipopolysaccharide exporter periplasmic protein complement(607154..607729) Escherichia coli O104:H4 str. 2009EL-2050 13691158 YP_006768278.1 CDS O3M_02995 NC_018650.1 607726 608292 R COG1778 Low specificity phosphatase (HAD superfamily); 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase complement(607726..608292) Escherichia coli O104:H4 str. 2009EL-2050 13691159 YP_006768279.1 CDS O3M_03000 NC_018650.1 608313 609299 R COG0794 Predicted sugar phosphate isomerase involved in capsule formation; D-arabinose 5-phosphate isomerase complement(608313..609299) Escherichia coli O104:H4 str. 2009EL-2050 13691160 YP_006768280.1 CDS O3M_03005 NC_018650.1 609313 610290 R COG0530 Ca2+/Na+ antiporter; calcium/sodium:proton antiporter complement(609313..610290) Escherichia coli O104:H4 str. 2009EL-2050 13691161 YP_006768281.1 CDS O3M_03010 NC_018650.1 610500 611309 D COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; ABC transporter ATP-binding protein 610500..611309 Escherichia coli O104:H4 str. 2009EL-2050 13691162 YP_006768282.1 CDS O3M_03015 NC_018650.1 611317 612099 D COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; toluene ABC transporter permease 611317..612099 Escherichia coli O104:H4 str. 2009EL-2050 13691163 YP_006768283.1 CDS O3M_03020 NC_018650.1 612104 612655 D COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; hypothetical protein 612104..612655 Escherichia coli O104:H4 str. 2009EL-2050 13691164 YP_006768284.1 CDS O3M_03025 NC_018650.1 612674 613309 D COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component; ABC transporter substrate-binding protein MlaC 612674..613309 Escherichia coli O104:H4 str. 2009EL-2050 13691165 YP_006768285.1 CDS O3M_03030 NC_018650.1 613309 613602 D COG3113 Predicted NTP binding protein (contains STAS domain); hypothetical protein 613309..613602 Escherichia coli O104:H4 str. 2009EL-2050 13691166 YP_006768286.1 CDS O3M_03035 NC_018650.1 613762 614016 D COG5007 Predicted transcriptional regulator, BolA superfamily; DNA-binding transcriptional regulator 613762..614016 Escherichia coli O104:H4 str. 2009EL-2050 13691167 YP_006768287.1 CDS O3M_03040 NC_018650.1 614071 615330 D COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 614071..615330 Escherichia coli O104:H4 str. 2009EL-2050 13691168 YP_006768288.1 CDS O3M_03045 NC_018650.1 615378 615656 R COG3423 Predicted transcriptional regulator; DNA-binding transcriptional regulator Nlp complement(615378..615656) Escherichia coli O104:H4 str. 2009EL-2050 13691169 YP_006768289.1 CDS O3M_03050 NC_018650.1 615884 616855 R COG0142 Geranylgeranyl pyrophosphate synthase; octaprenyl diphosphate synthase complement(615884..616855) Escherichia coli O104:H4 str. 2009EL-2050 13691170 YP_006768290.1 CDS rplU NC_018650.1 617114 617425 D COG0261 Ribosomal protein L21; 50S ribosomal protein L21 617114..617425 Escherichia coli O104:H4 str. 2009EL-2050 13691171 YP_006768291.1 CDS rpmA NC_018650.1 617446 617703 D COG0211 Ribosomal protein L27; 50S ribosomal protein L27 617446..617703 Escherichia coli O104:H4 str. 2009EL-2050 13691172 YP_006768292.1 CDS O3M_03065 NC_018650.1 617830 618795 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 617830..618795 Escherichia coli O104:H4 str. 2009EL-2050 13691173 YP_006768293.1 CDS obgE NC_018650.1 618811 619983 D COG0536 Predicted GTPase; GTPase CgtA 618811..619983 Escherichia coli O104:H4 str. 2009EL-2050 13691174 YP_006768294.1 CDS O3M_03075 NC_018650.1 620023 621456 R COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); D-alanyl-D-alanine carboxypeptidase complement(620023..621456) Escherichia coli O104:H4 str. 2009EL-2050 13691175 YP_006768295.1 CDS greA NC_018650.1 621704 622180 D COG0782 Transcription elongation factor; transcription elongation factor GreA 621704..622180 Escherichia coli O104:H4 str. 2009EL-2050 13691176 YP_006768296.1 CDS O3M_03085 NC_018650.1 622336 622629 R COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; RNA-binding protein YhbY complement(622336..622629) Escherichia coli O104:H4 str. 2009EL-2050 13691177 YP_006768297.1 CDS rrmJ NC_018650.1 622755 623384 D COG0293 23S rRNA methylase; 23S rRNA methyltransferase J 622755..623384 Escherichia coli O104:H4 str. 2009EL-2050 13691178 YP_006768298.1 CDS hflB NC_018650.1 623484 625418 D COG0465 ATP-dependent Zn proteases; ATP-dependent metalloprotease 623484..625418 Escherichia coli O104:H4 str. 2009EL-2050 13691179 YP_006768299.1 CDS folP NC_018650.1 625508 626356 D COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase 625508..626356 Escherichia coli O104:H4 str. 2009EL-2050 13691180 YP_006768300.1 CDS glmM NC_018650.1 626349 627686 D COG1109 Phosphomannomutase; phosphoglucosamine mutase 626349..627686 Escherichia coli O104:H4 str. 2009EL-2050 13691181 YP_006768301.1 CDS secG NC_018650.1 627914 628246 D COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 627914..628246 Escherichia coli O104:H4 str. 2009EL-2050 13691182 YP_006768302.1 CDS O3M_03115 NC_018650.1 628804 630429 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; hydrolase, inner membrane 628804..630429 Escherichia coli O104:H4 str. 2009EL-2050 13691184 YP_006768303.1 CDS O3M_03120 NC_018650.1 630437 631780 R COG0137 Argininosuccinate synthase; argininosuccinate synthase complement(630437..631780) Escherichia coli O104:H4 str. 2009EL-2050 13691185 YP_006768304.1 CDS O3M_03125 NC_018650.1 632411 632863 D COG0779 Uncharacterized protein conserved in bacteria; ribosome maturation protein RimP 632411..632863 Escherichia coli O104:H4 str. 2009EL-2050 13691187 YP_006768305.1 CDS nusA NC_018650.1 632891 634378 D COG0195 Transcription elongation factor; transcription elongation factor NusA 632891..634378 Escherichia coli O104:H4 str. 2009EL-2050 13691188 YP_006768306.1 CDS infB NC_018650.1 634403 637075 D COG0532 Translation initiation factor 2 (IF-2; GTPase); translation initiation factor IF-2 634403..637075 Escherichia coli O104:H4 str. 2009EL-2050 13691189 YP_006768307.1 CDS rbfA NC_018650.1 637239 637640 D COG0858 Ribosome-binding factor A; ribosome-binding factor A 637239..637640 Escherichia coli O104:H4 str. 2009EL-2050 13691190 YP_006768308.1 CDS truB NC_018650.1 637640 638584 D COG0130 Pseudouridine synthase; tRNA pseudouridine synthase B 637640..638584 Escherichia coli O104:H4 str. 2009EL-2050 13691191 YP_006768309.1 CDS rpsO NC_018650.1 638733 639002 D COG0184 Ribosomal protein S15P/S13E; 30S ribosomal protein S15 638733..639002 Escherichia coli O104:H4 str. 2009EL-2050 13691192 YP_006768310.1 CDS O3M_03155 NC_018650.1 639249 641384 D COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 639249..641384 Escherichia coli O104:H4 str. 2009EL-2050 13691193 YP_006768311.1 CDS O3M_03160 NC_018650.1 641493 642377 D COG4785 Lipoprotein NlpI, contains TPR repeats; lipoprotein NlpI 641493..642377 Escherichia coli O104:H4 str. 2009EL-2050 13691194 YP_006768312.1 CDS O3M_03165 NC_018650.1 642557 644446 D COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase DeaD 642557..644446 Escherichia coli O104:H4 str. 2009EL-2050 13691195 YP_006768313.1 CDS O3M_03170 NC_018650.1 644600 645844 D COG0814 Amino acid permeases; tryptophan permease 644600..645844 Escherichia coli O104:H4 str. 2009EL-2050 13691196 YP_006768314.1 CDS O3M_03175 NC_018650.1 645962 646969 R COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein complement(645962..646969) Escherichia coli O104:H4 str. 2009EL-2050 13691197 YP_006768315.1 CDS O3M_03180 NC_018650.1 647175 648053 R COG0826 Collagenase and related proteases; protease complement(647175..648053) Escherichia coli O104:H4 str. 2009EL-2050 13691198 YP_006768316.1 CDS O3M_03185 NC_018650.1 648062 649057 R COG0826 Collagenase and related proteases; peptidase, U32 family protein complement(648062..649057) Escherichia coli O104:H4 str. 2009EL-2050 13691199 YP_006768317.1 CDS O3M_03190 NC_018650.1 649266 649790 D COG3154 Putative lipid carrier protein; lipid carrier protein 649266..649790 Escherichia coli O104:H4 str. 2009EL-2050 13691200 YP_006768318.1 CDS O3M_03195 NC_018650.1 649784 650287 D COG3153 Predicted acetyltransferase; hypothetical protein 649784..650287 Escherichia coli O104:H4 str. 2009EL-2050 13691201 YP_006768319.1 CDS O3M_03200 NC_018650.1 650274 650576 R COG2827 Predicted endonuclease containing a URI domain; GIY-YIG nuclease superfamily protein complement(650274..650576) Escherichia coli O104:H4 str. 2009EL-2050 13691202 YP_006768320.1 CDS O3M_03205 NC_018650.1 650627 651070 D COG3787 Uncharacterized protein conserved in bacteria; hypothetical protein 650627..651070 Escherichia coli O104:H4 str. 2009EL-2050 13691203 YP_006768321.1 CDS O3M_03210 NC_018650.1 651050 651568 R COG0693 Putative intracellular protease/amidase; hypothetical protein complement(651050..651568) Escherichia coli O104:H4 str. 2009EL-2050 13691204 YP_006768322.1 CDS O3M_03215 NC_018650.1 651696 652331 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; nucleoside-diphosphate-sugar epimerase 651696..652331 Escherichia coli O104:H4 str. 2009EL-2050 13691205 YP_006768323.1 CDS O3M_03220 NC_018650.1 652404 653444 D COG0701 Predicted permeases; permease 652404..653444 Escherichia coli O104:H4 str. 2009EL-2050 13691206 YP_006768324.1 CDS O3M_03225 NC_018650.1 653558 654133 R COG2823 Predicted periplasmic or secreted lipoprotein; outer membrane lipoprotein complement(653558..654133) Escherichia coli O104:H4 str. 2009EL-2050 13691207 YP_006768325.1 CDS O3M_03230 NC_018650.1 654143 654733 R COG0279 Phosphoheptose isomerase; DnaA initiator-associating protein DiaA complement(654143..654733) Escherichia coli O104:H4 str. 2009EL-2050 13691208 YP_006768326.1 CDS O3M_03235 NC_018650.1 654753 655148 R COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein complement(654753..655148) Escherichia coli O104:H4 str. 2009EL-2050 13691209 YP_006768327.1 CDS O3M_03240 NC_018650.1 655106 657142 R COG3107 Putative lipoprotein; LppC family lipoprotein complement(655106..657142) Escherichia coli O104:H4 str. 2009EL-2050 13691210 YP_006768328.1 CDS O3M_03245 NC_018650.1 657206 658066 D COG0313 Predicted methyltransferases; SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase 657206..658066 Escherichia coli O104:H4 str. 2009EL-2050 13691211 YP_006768329.1 CDS O3M_03250 NC_018650.1 658109 659200 R COG3539 P pilus assembly protein, pilin FimA; fimbrial protein complement(658109..659200) Escherichia coli O104:H4 str. 2009EL-2050 13691212 YP_006768330.1 CDS O3M_03255 NC_018650.1 659211 661727 R COG3188 P pilus assembly protein, porin PapC; outer membrane protein complement(659211..661727) Escherichia coli O104:H4 str. 2009EL-2050 13691213 YP_006768331.1 CDS O3M_03260 NC_018650.1 661757 662452 R COG3121 P pilus assembly protein, chaperone PapD; periplasmic pilin chaperone complement(661757..662452) Escherichia coli O104:H4 str. 2009EL-2050 13691214 YP_006768332.1 CDS O3M_03265 NC_018650.1 662532 663116 R COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein complement(662532..663116) Escherichia coli O104:H4 str. 2009EL-2050 13691215 YP_006768333.1 CDS O3M_03270 NC_018650.1 663516 664271 R COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; galactosamine-6-phosphate isomerase complement(663516..664271) Escherichia coli O104:H4 str. 2009EL-2050 13691216 YP_006768334.1 CDS O3M_03275 NC_018650.1 664272 665063 R COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system N-acetylgalactosamine-specific transporter subunit IID complement(664272..665063) Escherichia coli O104:H4 str. 2009EL-2050 13691217 YP_006768335.1 CDS O3M_03280 NC_018650.1 665053 665856 R COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system N-acetylgalactosamine-specific transporter subunit IIC complement(665053..665856) Escherichia coli O104:H4 str. 2009EL-2050 13691218 YP_006768336.1 CDS O3M_03285 NC_018650.1 665895 666371 R COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(665895..666371) Escherichia coli O104:H4 str. 2009EL-2050 13691219 YP_006768337.1 CDS kbaY NC_018650.1 666538 667398 R COG0191 Fructose/tagatose bisphosphate aldolase; tagatose-bisphosphate aldolase complement(666538..667398) Escherichia coli O104:H4 str. 2009EL-2050 13691220 YP_006768338.1 CDS O3M_03295 NC_018650.1 667411 668565 R COG2222 Predicted phosphosugar isomerases; tagatose-6-phosphate ketose/aldose isomerase complement(667411..668565) Escherichia coli O104:H4 str. 2009EL-2050 13691221 YP_006768339.1 CDS O3M_03300 NC_018650.1 668915 670048 R COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase complement(668915..670048) Escherichia coli O104:H4 str. 2009EL-2050 13691222 YP_006768340.1 CDS O3M_03305 NC_018650.1 670045 670479 R COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system transporter subunit IIA complement(670045..670479) Escherichia coli O104:H4 str. 2009EL-2050 13691223 YP_006768341.1 CDS O3M_03310 NC_018650.1 670497 671375 R COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system hexose/hexosamine family transporter permease IID complement(670497..671375) Escherichia coli O104:H4 str. 2009EL-2050 13691224 YP_006768342.1 CDS O3M_03315 NC_018650.1 671365 672144 R COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system N-acetylgalactosamine-specific transporter subunit IIC complement(671365..672144) Escherichia coli O104:H4 str. 2009EL-2050 13691225 YP_006768343.1 CDS O3M_03320 NC_018650.1 672155 672628 R COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(672155..672628) Escherichia coli O104:H4 str. 2009EL-2050 13691226 YP_006768344.1 CDS O3M_03325 NC_018650.1 672651 673931 R COG4573 Predicted tagatose 6-phosphate kinase; tagatose 6-phosphate aldolase subunit KbaZ complement(672651..673931) Escherichia coli O104:H4 str. 2009EL-2050 13691227 YP_006768345.1 CDS O3M_03330 NC_018650.1 674180 674989 D COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional regulator AgaR 674180..674989 Escherichia coli O104:H4 str. 2009EL-2050 13691228 YP_006768346.1 CDS O3M_03335 NC_018650.1 675044 675508 R hypothetical protein complement(675044..675508) Escherichia coli O104:H4 str. 2009EL-2050 13691229 YP_006768347.1 CDS O3M_03340 NC_018650.1 675508 675843 R COG2002 Regulators of stationary/sporulation gene expression; regulator PrlF complement(675508..675843) Escherichia coli O104:H4 str. 2009EL-2050 13691230 YP_006768348.1 CDS O3M_03345 NC_018650.1 675992 677563 R COG2721 Altronate dehydratase; galactarate dehydratase complement(675992..677563) Escherichia coli O104:H4 str. 2009EL-2050 13691231 YP_006768349.1 CDS O3M_03350 NC_018650.1 677937 679271 D COG0477 Permeases of the major facilitator superfamily; galactarate transporter 677937..679271 Escherichia coli O104:H4 str. 2009EL-2050 13691232 YP_006768350.1 CDS O3M_03355 NC_018650.1 679287 680057 D COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; alpha-dehydro-beta-deoxy-D-glucarate aldolase 679287..680057 Escherichia coli O104:H4 str. 2009EL-2050 13691233 YP_006768351.1 CDS garR NC_018650.1 680087 680977 D COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; tartronate semialdehyde reductase 680087..680977 Escherichia coli O104:H4 str. 2009EL-2050 13691234 YP_006768352.1 CDS O3M_03365 NC_018650.1 681074 682219 D COG1929 Glycerate kinase; glycerate kinase 681074..682219 Escherichia coli O104:H4 str. 2009EL-2050 13691235 YP_006768353.1 CDS O3M_03370 NC_018650.1 682976 683956 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(682976..683956) Escherichia coli O104:H4 str. 2009EL-2050 13691236 YP_006768354.1 CDS O3M_03375 NC_018650.1 684294 685481 R hypothetical protein complement(684294..685481) Escherichia coli O104:H4 str. 2009EL-2050 13691237 YP_006768355.1 CDS O3M_03380 NC_018650.1 685503 686042 R COG0443 Molecular chaperone; hypothetical protein complement(685503..686042) Escherichia coli O104:H4 str. 2009EL-2050 13691238 YP_006768356.1 CDS O3M_03385 NC_018650.1 686298 686516 R DNA-binding transcriptional activator TdcR complement(686298..686516) Escherichia coli O104:H4 str. 2009EL-2050 13691239 YP_006768357.1 CDS O3M_03390 NC_018650.1 686831 687769 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator TdcA 686831..687769 Escherichia coli O104:H4 str. 2009EL-2050 13691240 YP_006768358.1 CDS O3M_03395 NC_018650.1 687868 688857 D COG1171 Threonine dehydratase; threonine dehydratase 687868..688857 Escherichia coli O104:H4 str. 2009EL-2050 13691241 YP_006768359.1 CDS O3M_03400 NC_018650.1 688879 690210 D COG0814 Amino acid permeases; threonine/serine transporter TdcC 688879..690210 Escherichia coli O104:H4 str. 2009EL-2050 13691242 YP_006768360.1 CDS O3M_03405 NC_018650.1 690236 691444 D COG0282 Acetate kinase; propionate/acetate kinase 690236..691444 Escherichia coli O104:H4 str. 2009EL-2050 13691243 YP_006768361.1 CDS O3M_03410 NC_018650.1 691478 693772 D COG1882 Pyruvate-formate lyase; Keto-acid formate acetyltransferase 691478..693772 Escherichia coli O104:H4 str. 2009EL-2050 13691244 YP_006768362.1 CDS O3M_03415 NC_018650.1 693786 694175 D COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease L-PSP 693786..694175 Escherichia coli O104:H4 str. 2009EL-2050 13691245 YP_006768363.1 CDS O3M_03420 NC_018650.1 694247 695611 D COG1760 L-serine deaminase; L-serine dehydratase TdcG 694247..695611 Escherichia coli O104:H4 str. 2009EL-2050 13691246 YP_006768364.1 CDS O3M_03425 NC_018650.1 695886 697217 D COG0814 Amino acid permeases; transporter 695886..697217 Escherichia coli O104:H4 str. 2009EL-2050 13691247 YP_006768365.1 CDS O3M_03430 NC_018650.1 697245 698555 D COG3681 Uncharacterized conserved protein; hypothetical protein 697245..698555 Escherichia coli O104:H4 str. 2009EL-2050 13691248 YP_006768366.1 CDS O3M_03435 NC_018650.1 698616 698780 R hypothetical protein complement(698616..698780) Escherichia coli O104:H4 str. 2009EL-2050 13691249 YP_006768367.1 CDS O3M_03440 NC_018650.1 698803 699504 R COG1741 Pirin-related protein; pirin-related protein complement(698803..699504) Escherichia coli O104:H4 str. 2009EL-2050 13691250 YP_006768368.1 CDS O3M_03445 NC_018650.1 699609 700505 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 699609..700505 Escherichia coli O104:H4 str. 2009EL-2050 13691251 YP_006768369.1 CDS O3M_03450 NC_018650.1 700549 701052 R COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' complement(700549..701052) Escherichia coli O104:H4 str. 2009EL-2050 13691252 YP_006768370.1 CDS O3M_03455 NC_018650.1 700971 701246 R COG3677 Transposase and inactivated derivatives; InsA complement(700971..701246) Escherichia coli O104:H4 str. 2009EL-2050 13691253 YP_006768371.1 CDS O3M_03460 NC_018650.1 701356 701721 R COG3152 Predicted membrane protein; hypothetical protein complement(701356..701721) Escherichia coli O104:H4 str. 2009EL-2050 13691254 YP_006768372.1 CDS O3M_03465 NC_018650.1 702014 703000 R COG0435 Predicted glutathione S-transferase; transferase complement(702014..703000) Escherichia coli O104:H4 str. 2009EL-2050 13691255 YP_006768373.1 CDS O3M_03470 NC_018650.1 703070 703462 R COG2259 Predicted membrane protein; hypothetical protein complement(703070..703462) Escherichia coli O104:H4 str. 2009EL-2050 13691256 YP_006768374.1 CDS O3M_03475 NC_018650.1 703648 703947 R hypothetical protein complement(703648..703947) Escherichia coli O104:H4 str. 2009EL-2050 13691257 YP_006768375.1 CDS O3M_03480 NC_018650.1 703937 704341 R hypothetical protein complement(703937..704341) Escherichia coli O104:H4 str. 2009EL-2050 13691258 YP_006768376.1 CDS O3M_03485 NC_018650.1 704344 704649 R COG4575 Uncharacterized conserved protein; hypothetical protein complement(704344..704649) Escherichia coli O104:H4 str. 2009EL-2050 13691259 YP_006768377.1 CDS O3M_03490 NC_018650.1 704687 705055 R hypothetical protein complement(704687..705055) Escherichia coli O104:H4 str. 2009EL-2050 13691260 YP_006768378.1 CDS O3M_03495 NC_018650.1 705202 705585 R EnvZ/OmpR regulon moderator complement(705202..705585) Escherichia coli O104:H4 str. 2009EL-2050 13691261 YP_006768379.1 CDS O3M_03500 NC_018650.1 705589 706251 R COG0586 Uncharacterized membrane-associated protein; hypothetical protein complement(705589..706251) Escherichia coli O104:H4 str. 2009EL-2050 13691262 YP_006768380.1 CDS O3M_03505 NC_018650.1 706596 707372 R COG2186 Transcriptional regulators; DNA-binding transcriptional repressor ExuR complement(706596..707372) Escherichia coli O104:H4 str. 2009EL-2050 13691263 YP_006768381.1 CDS O3M_03510 NC_018650.1 707668 708384 D fimbrial protein 707668..708384 Escherichia coli O104:H4 str. 2009EL-2050 13691264 YP_006768382.1 CDS O3M_03515 NC_018650.1 708414 708914 D fimbrial subunit 708414..708914 Escherichia coli O104:H4 str. 2009EL-2050 13691265 YP_006768383.1 CDS O3M_03520 NC_018650.1 708988 711690 D hypothetical protein 708988..711690 Escherichia coli O104:H4 str. 2009EL-2050 13691266 YP_006768384.1 CDS O3M_03525 NC_018650.1 711687 712775 D hypothetical protein 711687..712775 Escherichia coli O104:H4 str. 2009EL-2050 13691267 YP_006768385.1 CDS O3M_03530 NC_018650.1 712863 714161 R COG0477 Permeases of the major facilitator superfamily; hexuronate transporter complement(712863..714161) Escherichia coli O104:H4 str. 2009EL-2050 13691268 YP_006768386.1 CDS O3M_03535 NC_018650.1 714644 716056 D COG1904 Glucuronate isomerase; glucuronate isomerase 714644..716056 Escherichia coli O104:H4 str. 2009EL-2050 13691269 YP_006768387.1 CDS O3M_03540 NC_018650.1 716071 717558 D COG2721 Altronate dehydratase; altronate hydrolase 716071..717558 Escherichia coli O104:H4 str. 2009EL-2050 13691270 YP_006768388.1 CDS O3M_03545 NC_018650.1 717641 718192 D inner membrane protein 717641..718192 Escherichia coli O104:H4 str. 2009EL-2050 13691271 YP_006768389.1 CDS O3M_03550 NC_018650.1 718197 719441 R COG3633 Na+/serine symporter; serine/threonine transporter SstT complement(718197..719441) Escherichia coli O104:H4 str. 2009EL-2050 13691272 YP_006768390.1 CDS O3M_03555 NC_018650.1 719840 720805 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; inner membrane protein complement(719840..720805) Escherichia coli O104:H4 str. 2009EL-2050 13691273 YP_006768391.1 CDS O3M_03560 NC_018650.1 721088 722074 R COG0673 Predicted dehydrogenases and related proteins; NAD(P)-binding dehydrogenase complement(721088..722074) Escherichia coli O104:H4 str. 2009EL-2050 13691274 YP_006768392.1 CDS O3M_03565 NC_018650.1 722153 722836 R COG2949 Uncharacterized membrane protein; thioredoxin-like protein complement(722153..722836) Escherichia coli O104:H4 str. 2009EL-2050 13691275 YP_006768393.1 CDS O3M_03570 NC_018650.1 722913 723416 R COG1451 Predicted metal-dependent hydrolase; hypothetical protein complement(722913..723416) Escherichia coli O104:H4 str. 2009EL-2050 13691276 YP_006768394.1 CDS O3M_03575 NC_018650.1 723501 724637 D COG2813 16S RNA G1207 methylase RsmC; SAM-dependent 23S ribosomal RNA mG1835 methyltransferase 723501..724637 Escherichia coli O104:H4 str. 2009EL-2050 13691277 YP_006768395.1 CDS O3M_03580 NC_018650.1 724741 724911 D hypothetical protein 724741..724911 Escherichia coli O104:H4 str. 2009EL-2050 13691278 YP_006768396.1 CDS O3M_03585 NC_018650.1 724908 725324 D COG5499 Predicted transcription regulator containing HTH domain; DNA-binding transcriptional regulator 724908..725324 Escherichia coli O104:H4 str. 2009EL-2050 13691279 YP_006768397.1 CDS O3M_03590 NC_018650.1 725369 727387 R COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; 2,4-dienoyl-CoA reductase complement(725369..727387) Escherichia coli O104:H4 str. 2009EL-2050 13691280 YP_006768398.1 CDS O3M_03595 NC_018650.1 727713 730064 R COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; alpha-glucosidase complement(727713..730064) Escherichia coli O104:H4 str. 2009EL-2050 13691281 YP_006768399.1 CDS O3M_03600 NC_018650.1 730081 731151 R hypothetical protein complement(730081..731151) Escherichia coli O104:H4 str. 2009EL-2050 13691282 YP_006768400.1 CDS O3M_03605 NC_018650.1 731285 732718 R COG0531 Amino acid transporters; transporter complement(731285..732718) Escherichia coli O104:H4 str. 2009EL-2050 13691283 YP_006768401.1 CDS ebgC NC_018650.1 732781 733230 R COG2731 Beta-galactosidase, beta subunit; cryptic beta-D-galactosidase subunit beta complement(732781..733230) Escherichia coli O104:H4 str. 2009EL-2050 13691284 YP_006768402.1 CDS ebgA NC_018650.1 733227 736319 R COG3250 Beta-galactosidase/beta-glucuronidase; cryptic beta-D-galactosidase subunit alpha complement(733227..736319) Escherichia coli O104:H4 str. 2009EL-2050 13691285 YP_006768403.1 CDS O3M_03620 NC_018650.1 736503 737486 R COG1609 Transcriptional regulators; DNA-binding transcriptional repressor EbgR complement(736503..737486) Escherichia coli O104:H4 str. 2009EL-2050 13691286 YP_006768404.1 CDS O3M_03625 NC_018650.1 737705 738037 D COG0073 EMAP domain; tRNA-binding protein 737705..738037 Escherichia coli O104:H4 str. 2009EL-2050 13691287 YP_006768405.1 CDS O3M_03630 NC_018650.1 738079 739485 R COG4992 Ornithine/acetylornithine aminotransferase; putrescine--2-oxoglutarate aminotransferase complement(738079..739485) Escherichia coli O104:H4 str. 2009EL-2050 13691288 YP_006768406.1 CDS O3M_03635 NC_018650.1 739876 741396 D COG2202 FOG: PAS/PAC domain; signal transducer for aerotaxis/methyl accepting chemotaxis protein 739876..741396 Escherichia coli O104:H4 str. 2009EL-2050 13691289 YP_006768407.1 CDS O3M_03640 NC_018650.1 741550 742173 R COG1695 Predicted transcriptional regulators; transcriptional regulator complement(741550..742173) Escherichia coli O104:H4 str. 2009EL-2050 13691290 YP_006768408.1 CDS O3M_03645 NC_018650.1 742450 743214 D COG2375 Siderophore-interacting protein; siderophore-interacting protein 742450..743214 Escherichia coli O104:H4 str. 2009EL-2050 13691291 YP_006768409.1 CDS O3M_03650 NC_018650.1 743468 743974 D COG3663 G:T/U mismatch-specific DNA glycosylase; G/U mismatch-specific DNA glycosylase 743468..743974 Escherichia coli O104:H4 str. 2009EL-2050 13691293 YP_006768410.1 CDS O3M_03655 NC_018650.1 744052 745893 R COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor RpoD complement(744052..745893) Escherichia coli O104:H4 str. 2009EL-2050 13691294 YP_006768411.1 CDS dnaG NC_018650.1 746088 747833 R COG0358 DNA primase (bacterial type); DNA primase complement(746088..747833) Escherichia coli O104:H4 str. 2009EL-2050 13691295 YP_006768412.1 CDS rpsU NC_018650.1 747944 748159 R COG0828 Ribosomal protein S21; 30S ribosomal protein S21 complement(747944..748159) Escherichia coli O104:H4 str. 2009EL-2050 13691296 YP_006768413.1 CDS O3M_03670 NC_018650.1 748396 749409 D COG0533 Metal-dependent proteases with possible chaperone activity; UGMP family protein 748396..749409 Escherichia coli O104:H4 str. 2009EL-2050 13691297 YP_006768414.1 CDS O3M_03675 NC_018650.1 749452 750915 R COG0471 Di- and tricarboxylate transporters; tartrate:succinate antiporter complement(749452..750915) Escherichia coli O104:H4 str. 2009EL-2050 13691298 YP_006768415.1 CDS O3M_03680 NC_018650.1 750964 751569 R COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain; L(+)-tartrate dehydratase subunit beta complement(750964..751569) Escherichia coli O104:H4 str. 2009EL-2050 13691299 YP_006768416.1 CDS O3M_03685 NC_018650.1 751566 752477 R COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; tartrate dehydratase subunit alpha complement(751566..752477) Escherichia coli O104:H4 str. 2009EL-2050 13691300 YP_006768417.1 CDS O3M_03690 NC_018650.1 752684 753616 D COG0583 Transcriptional regulator; transcriptional activator TtdR 752684..753616 Escherichia coli O104:H4 str. 2009EL-2050 13691301 YP_006768418.1 CDS O3M_03695 NC_018650.1 753629 754246 R COG0344 Predicted membrane protein; glycerol-3-phosphate acyltransferase PlsY complement(753629..754246) Escherichia coli O104:H4 str. 2009EL-2050 13691302 YP_006768419.1 CDS folB NC_018650.1 754351 754719 D COG1539 Dihydroneopterin aldolase; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 754351..754719 Escherichia coli O104:H4 str. 2009EL-2050 13691303 YP_006768420.1 CDS O3M_03705 NC_018650.1 754810 755631 D COG1968 Uncharacterized bacitracin resistance protein; undecaprenyl pyrophosphate phosphatase 754810..755631 Escherichia coli O104:H4 str. 2009EL-2050 13691304 YP_006768421.1 CDS cca NC_018650.1 755794 757032 R COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase complement(755794..757032) Escherichia coli O104:H4 str. 2009EL-2050 13691305 YP_006768422.1 CDS O3M_03715 NC_018650.1 757096 757716 R COG3103 SH3 domain protein; SH3 domain-containing protein complement(757096..757716) Escherichia coli O104:H4 str. 2009EL-2050 13691306 YP_006768423.1 CDS O3M_03720 NC_018650.1 757958 759259 D COG3025 Uncharacterized conserved protein; adenylate cyclase 757958..759259 Escherichia coli O104:H4 str. 2009EL-2050 13691307 YP_006768424.1 CDS O3M_03725 NC_018650.1 759282 762122 D COG1391 Glutamine synthetase adenylyltransferase; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 759282..762122 Escherichia coli O104:H4 str. 2009EL-2050 13691308 YP_006768425.1 CDS O3M_03730 NC_018650.1 762170 763603 D COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 762170..763603 Escherichia coli O104:H4 str. 2009EL-2050 13691309 YP_006768426.1 CDS O3M_03735 NC_018650.1 764397 766058 R COG2268 Uncharacterized protein conserved in bacteria; hypothetical protein complement(764397..766058) Escherichia coli O104:H4 str. 2009EL-2050 13691310 YP_006768427.1 CDS O3M_03740 NC_018650.1 766085 766714 R inner membrane protein complement(766085..766714) Escherichia coli O104:H4 str. 2009EL-2050 13691311 YP_006768428.1 CDS O3M_03745 NC_018650.1 766983 767183 D glycogen synthesis protein GlgS 766983..767183 Escherichia coli O104:H4 str. 2009EL-2050 13691312 YP_006768429.1 CDS O3M_03750 NC_018650.1 767226 768290 R hypothetical protein complement(767226..768290) Escherichia coli O104:H4 str. 2009EL-2050 13691313 YP_006768430.1 CDS O3M_03755 NC_018650.1 768292 769041 R COG3121 P pilus assembly protein, chaperone PapD; periplasmic pilin chaperone complement(768292..769041) Escherichia coli O104:H4 str. 2009EL-2050 13691314 YP_006768431.1 CDS O3M_03760 NC_018650.1 769057 771561 R COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein complement(769057..771561) Escherichia coli O104:H4 str. 2009EL-2050 13691315 YP_006768432.1 CDS O3M_03765 NC_018650.1 771621 772172 R COG3539 P pilus assembly protein, pilin FimA; fimbrial protein complement(771621..772172) Escherichia coli O104:H4 str. 2009EL-2050 13691316 YP_006768433.1 CDS O3M_03770 NC_018650.1 772455 772745 R COG2960 Uncharacterized protein conserved in bacteria; hypothetical protein complement(772455..772745) Escherichia coli O104:H4 str. 2009EL-2050 13691317 YP_006768434.1 CDS ribB NC_018650.1 773119 773772 D COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase 773119..773772 Escherichia coli O104:H4 str. 2009EL-2050 13691318 YP_006768435.1 CDS O3M_03780 NC_018650.1 774033 774203 D hypothetical protein 774033..774203 Escherichia coli O104:H4 str. 2009EL-2050 13691319 YP_006768436.1 CDS O3M_03785 NC_018650.1 774261 775034 R COG0428 Predicted divalent heavy-metal cations transporter; zinc transporter ZupT complement(774261..775034) Escherichia coli O104:H4 str. 2009EL-2050 13691320 YP_006768437.1 CDS O3M_03790 NC_018650.1 775177 775965 D COG3384 Uncharacterized conserved protein; LigB family dioxygenase 775177..775965 Escherichia coli O104:H4 str. 2009EL-2050 13691321 YP_006768438.1 CDS O3M_03795 NC_018650.1 776003 777163 R COG0754 Glutathionylspermidine synthase; hypothetical protein complement(776003..777163) Escherichia coli O104:H4 str. 2009EL-2050 13691322 YP_006768439.1 CDS O3M_03800 NC_018650.1 777169 777840 R COG5463 Predicted integral membrane protein; hypothetical protein complement(777169..777840) Escherichia coli O104:H4 str. 2009EL-2050 13691323 YP_006768440.1 CDS tolC NC_018650.1 777988 779469 R COG1538 Outer membrane protein; outer membrane channel protein complement(777988..779469) Escherichia coli O104:H4 str. 2009EL-2050 13691324 YP_006768441.1 CDS nudF NC_018650.1 779674 780303 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; ADP-ribose pyrophosphatase NudF 779674..780303 Escherichia coli O104:H4 str. 2009EL-2050 13691325 YP_006768442.1 CDS O3M_03815 NC_018650.1 780304 780726 D COG3151 Uncharacterized protein conserved in bacteria; dehydrogenase 780304..780726 Escherichia coli O104:H4 str. 2009EL-2050 13691326 YP_006768443.1 CDS O3M_03820 NC_018650.1 780751 781578 D COG1409 Predicted phosphohydrolases; cyclic 3',5'-adenosine monophosphate phosphodiesterase 780751..781578 Escherichia coli O104:H4 str. 2009EL-2050 13691327 YP_006768444.1 CDS O3M_03825 NC_018650.1 781578 782159 D COG3150 Predicted esterase; esterase YqiA 781578..782159 Escherichia coli O104:H4 str. 2009EL-2050 13691328 YP_006768445.1 CDS O3M_03830 NC_018650.1 782188 784080 D COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA topoisomerase IV subunit B 782188..784080 Escherichia coli O104:H4 str. 2009EL-2050 13691329 YP_006768446.1 CDS O3M_03835 NC_018650.1 784128 784442 R COG1359 Uncharacterized conserved protein; hypothetical protein complement(784128..784442) Escherichia coli O104:H4 str. 2009EL-2050 13691330 YP_006768447.1 CDS O3M_03840 NC_018650.1 784473 785054 R COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); Modulator of drug activity B complement(784473..785054) Escherichia coli O104:H4 str. 2009EL-2050 13691331 YP_006768448.1 CDS O3M_03845 NC_018650.1 785373 785705 D hypothetical protein 785373..785705 Escherichia coli O104:H4 str. 2009EL-2050 13691332 YP_006768449.1 CDS O3M_03850 NC_018650.1 785751 787100 R COG0642 Signal transduction histidine kinase; sensor protein QseC complement(785751..787100) Escherichia coli O104:H4 str. 2009EL-2050 13691333 YP_006768450.1 CDS O3M_03855 NC_018650.1 787097 787756 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator QseB complement(787097..787756) Escherichia coli O104:H4 str. 2009EL-2050 13691334 YP_006768451.1 CDS O3M_03860 NC_018650.1 787908 788300 D COG3111 Uncharacterized conserved protein; hypothetical protein 787908..788300 Escherichia coli O104:H4 str. 2009EL-2050 13691335 YP_006768452.1 CDS O3M_03865 NC_018650.1 788353 788835 D COG3449 DNA gyrase inhibitor; transcriptional regulator 788353..788835 Escherichia coli O104:H4 str. 2009EL-2050 13691336 YP_006768453.1 CDS O3M_03870 NC_018650.1 789381 791639 D COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA topoisomerase IV subunit A 789381..791639 Escherichia coli O104:H4 str. 2009EL-2050 13691337 YP_006768454.1 CDS O3M_03875 NC_018650.1 791872 792609 D COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 791872..792609 Escherichia coli O104:H4 str. 2009EL-2050 13691338 YP_006768455.1 CDS O3M_03880 NC_018650.1 792684 794096 D COG2132 Putative multicopper oxidases; FtsI repressor 792684..794096 Escherichia coli O104:H4 str. 2009EL-2050 13691339 YP_006768456.1 CDS O3M_03885 NC_018650.1 794207 796426 D COG1032 Fe-S oxidoreductase; hypothetical protein 794207..796426 Escherichia coli O104:H4 str. 2009EL-2050 13691340 YP_006768457.1 CDS O3M_03890 NC_018650.1 796469 796726 R outer membrane lipoprotein complement(796469..796726) Escherichia coli O104:H4 str. 2009EL-2050 13691341 YP_006768458.1 CDS O3M_03895 NC_018650.1 796777 797703 R hypothetical protein complement(796777..797703) Escherichia coli O104:H4 str. 2009EL-2050 13691342 YP_006768459.1 CDS dkgA NC_018650.1 797903 798730 R COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-diketo-D-gluconate reductase A complement(797903..798730) Escherichia coli O104:H4 str. 2009EL-2050 13691343 YP_006768460.1 CDS O3M_03905 NC_018650.1 798835 799998 R COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; aldehyde reductase complement(798835..799998) Escherichia coli O104:H4 str. 2009EL-2050 13691344 YP_006768461.1 CDS O3M_03910 NC_018650.1 800049 800195 D hypothetical protein 800049..800195 Escherichia coli O104:H4 str. 2009EL-2050 13691345 YP_006768462.1 CDS O3M_03915 NC_018650.1 800135 801091 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 800135..801091 Escherichia coli O104:H4 str. 2009EL-2050 13691346 YP_006768463.1 CDS O3M_03920 NC_018650.1 801131 801790 R COG0586 Uncharacterized membrane-associated protein; hypothetical protein complement(801131..801790) Escherichia coli O104:H4 str. 2009EL-2050 13691347 YP_006768464.1 CDS O3M_03925 NC_018650.1 801930 803117 R COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine beta-lyase complement(801930..803117) Escherichia coli O104:H4 str. 2009EL-2050 13691348 YP_006768465.1 CDS O3M_03930 NC_018650.1 803369 804103 D COG0811 Biopolymer transport proteins; biopolymer transport protein ExbB 803369..804103 Escherichia coli O104:H4 str. 2009EL-2050 13691349 YP_006768466.1 CDS O3M_03935 NC_018650.1 804110 804535 D COG0848 Biopolymer transport protein; biopolymer transport protein ExbD 804110..804535 Escherichia coli O104:H4 str. 2009EL-2050 13691350 YP_006768467.1 CDS O3M_03940 NC_018650.1 804574 805458 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase complement(804574..805458) Escherichia coli O104:H4 str. 2009EL-2050 13691351 YP_006768468.1 CDS O3M_03945 NC_018650.1 805649 806143 D COG2862 Predicted membrane protein; hypothetical protein 805649..806143 Escherichia coli O104:H4 str. 2009EL-2050 13691352 YP_006768469.1 CDS O3M_03950 NC_018650.1 806183 807223 R COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); L-glyceraldehyde 3-phosphate reductase complement(806183..807223) Escherichia coli O104:H4 str. 2009EL-2050 13691353 YP_006768470.1 CDS O3M_03955 NC_018650.1 807380 808267 D COG0412 Dienelactone hydrolase and related enzymes; hypothetical protein 807380..808267 Escherichia coli O104:H4 str. 2009EL-2050 13691354 YP_006768471.1 CDS O3M_03960 NC_018650.1 808386 808673 D hypothetical protein 808386..808673 Escherichia coli O104:H4 str. 2009EL-2050 13691355 YP_006768472.1 CDS O3M_03965 NC_018650.1 808862 809980 D COG1740 Ni,Fe-hydrogenase I small subunit; hydrogenase 2 small subunit 808862..809980 Escherichia coli O104:H4 str. 2009EL-2050 13691356 YP_006768473.1 CDS O3M_03970 NC_018650.1 809983 810969 D COG0437 Fe-S-cluster-containing hydrogenase components 1; hydrogenase 2 protein HybA 809983..810969 Escherichia coli O104:H4 str. 2009EL-2050 13691357 YP_006768474.1 CDS O3M_03975 NC_018650.1 810959 812137 D COG5557 Polysulphide reductase; hydrogenase 2 b cytochrome subunit 810959..812137 Escherichia coli O104:H4 str. 2009EL-2050 13691358 YP_006768475.1 CDS O3M_03980 NC_018650.1 812134 813837 D COG0374 Ni,Fe-hydrogenase I large subunit; hydrogenase 2 large subunit 812134..813837 Escherichia coli O104:H4 str. 2009EL-2050 13691359 YP_006768476.1 CDS hybD NC_018650.1 813837 814331 D COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 2 maturation endopeptidase 813837..814331 Escherichia coli O104:H4 str. 2009EL-2050 13691360 YP_006768477.1 CDS O3M_03990 NC_018650.1 814324 814812 D hydrogenase 2-specific chaperone 814324..814812 Escherichia coli O104:H4 str. 2009EL-2050 13691361 YP_006768478.1 CDS O3M_03995 NC_018650.1 814805 815146 D COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); hydrogenase nickel incorporation protein HybF 814805..815146 Escherichia coli O104:H4 str. 2009EL-2050 13691362 YP_006768479.1 CDS O3M_04000 NC_018650.1 815159 815407 D COG0298 Hydrogenase maturation factor; hydrogenase 2 accessory protein HypG 815159..815407 Escherichia coli O104:H4 str. 2009EL-2050 13691363 YP_006768480.1 CDS O3M_04005 NC_018650.1 815529 816509 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(815529..816509) Escherichia coli O104:H4 str. 2009EL-2050 13691364 YP_006768481.1 CDS O3M_04010 NC_018650.1 816809 817675 R COG0625 Glutathione S-transferase; S-transferase complement(816809..817675) Escherichia coli O104:H4 str. 2009EL-2050 13691365 YP_006768482.1 CDS O3M_04015 NC_018650.1 817880 819739 D COG0754 Glutathionylspermidine synthase; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 817880..819739 Escherichia coli O104:H4 str. 2009EL-2050 13691366 YP_006768483.1 CDS O3M_04020 NC_018650.1 820031 821530 D COG0306 Phosphate/sulphate permeases; phosphate transporter 820031..821530 Escherichia coli O104:H4 str. 2009EL-2050 13691367 YP_006768484.1 CDS O3M_04025 NC_018650.1 821579 822271 R COG0125 Thymidylate kinase; hypothetical protein complement(821579..822271) Escherichia coli O104:H4 str. 2009EL-2050 13691368 YP_006768485.1 CDS O3M_04030 NC_018650.1 822445 823158 D nucleoside triphosphate hydrolase domain; COG0125 Thymidylate kinase; lipoprotein 822445..823158 Escherichia coli O104:H4 str. 2009EL-2050 13691369 YP_006768486.1 CDS O3M_04035 NC_018650.1 823190 823948 D COG0178 Excinuclease ATPase subunit; hypothetical protein 823190..823948 Escherichia coli O104:H4 str. 2009EL-2050 13691370 YP_006768487.1 CDS O3M_04040 NC_018650.1 823994 825343 D COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; inner membrane protein 823994..825343 Escherichia coli O104:H4 str. 2009EL-2050 13691371 YP_006768488.1 CDS O3M_04045 NC_018650.1 825343 826167 D COG0372 Citrate synthase; hypothetical protein 825343..826167 Escherichia coli O104:H4 str. 2009EL-2050 13691372 YP_006768489.1 CDS O3M_04050 NC_018650.1 826179 826739 D COG3054 Predicted transcriptional regulator; transcriptional regulator 826179..826739 Escherichia coli O104:H4 str. 2009EL-2050 13691373 YP_006768490.1 CDS O3M_04055 NC_018650.1 826770 827840 D COG0795 Predicted permeases; hypothetical protein 826770..827840 Escherichia coli O104:H4 str. 2009EL-2050 13691374 YP_006768491.1 CDS O3M_04060 NC_018650.1 827837 828916 D COG0795 Predicted permeases; hypothetical protein 827837..828916 Escherichia coli O104:H4 str. 2009EL-2050 13691375 YP_006768492.1 CDS O3M_04065 NC_018650.1 828951 830123 R COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; hypothetical protein complement(828951..830123) Escherichia coli O104:H4 str. 2009EL-2050 13691376 YP_006768493.1 CDS O3M_04070 NC_018650.1 830123 830371 R COG0236 Acyl carrier protein; hypothetical protein complement(830123..830371) Escherichia coli O104:H4 str. 2009EL-2050 13691377 YP_006768494.1 CDS O3M_04075 NC_018650.1 830403 831317 R COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein complement(830403..831317) Escherichia coli O104:H4 str. 2009EL-2050 13691378 YP_006768495.1 CDS O3M_04080 NC_018650.1 831314 833002 R COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; acyl-CoA synthetase complement(831314..833002) Escherichia coli O104:H4 str. 2009EL-2050 13691379 YP_006768496.1 CDS O3M_04085 NC_018650.1 833406 834548 D DNA-binding transcriptional regulator 833406..834548 Escherichia coli O104:H4 str. 2009EL-2050 13691380 YP_006768497.1 CDS O3M_04090 NC_018650.1 834555 835319 R COG2186 Transcriptional regulators; DNA-binding transcriptional regulator GlcC complement(834555..835319) Escherichia coli O104:H4 str. 2009EL-2050 13691381 YP_006768498.1 CDS O3M_04095 NC_018650.1 835570 837069 D COG0277 FAD/FMN-containing dehydrogenases; glycolate oxidase subunit GlcD 835570..837069 Escherichia coli O104:H4 str. 2009EL-2050 13691382 YP_006768499.1 CDS glcE NC_018650.1 837069 838121 D COG0277 FAD/FMN-containing dehydrogenases; glycolate oxidase FAD binding subunit 837069..838121 Escherichia coli O104:H4 str. 2009EL-2050 13691383 YP_006768500.1 CDS glcF NC_018650.1 838132 839355 D COG0247 Fe-S oxidoreductase; glycolate oxidase iron-sulfur subunit 838132..839355 Escherichia coli O104:H4 str. 2009EL-2050 13691384 YP_006768501.1 CDS O3M_04110 NC_018650.1 839360 839764 D COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol; hypothetical protein 839360..839764 Escherichia coli O104:H4 str. 2009EL-2050 13691385 YP_006768502.1 CDS O3M_04115 NC_018650.1 839786 841957 D COG2225 Malate synthase; malate synthase G 839786..841957 Escherichia coli O104:H4 str. 2009EL-2050 13691386 YP_006768503.1 CDS O3M_04120 NC_018650.1 842313 843995 D COG1620 L-lactate permease; glycolate transporter 842313..843995 Escherichia coli O104:H4 str. 2009EL-2050 13691387 YP_006768504.1 CDS O3M_04125 NC_018650.1 844121 844330 R hypothetical protein complement(844121..844330) Escherichia coli O104:H4 str. 2009EL-2050 13691388 YP_006768505.1 CDS O3M_04130 NC_018650.1 844613 849046 D inner membrane lipoprotein 844613..849046 Escherichia coli O104:H4 str. 2009EL-2050 13691389 YP_006768506.1 CDS O3M_04135 NC_018650.1 849186 849995 D COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; bifunctional prepilin leader peptidase/methylase 849186..849995 Escherichia coli O104:H4 str. 2009EL-2050 13691390 YP_006768507.1 CDS O3M_04140 NC_018650.1 850061 850471 D hypothetical protein 850061..850471 Escherichia coli O104:H4 str. 2009EL-2050 13691391 YP_006768508.1 CDS O3M_04145 NC_018650.1 850489 851448 D COG3031 Type II secretory pathway, component PulC; type II secretion protein GspC 850489..851448 Escherichia coli O104:H4 str. 2009EL-2050 13691392 YP_006768509.1 CDS O3M_04150 NC_018650.1 851478 853538 D COG1450 Type II secretory pathway, component PulD; general secretion pathway protein D 851478..853538 Escherichia coli O104:H4 str. 2009EL-2050 13691393 YP_006768510.1 CDS O3M_04155 NC_018650.1 853538 855031 D COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; general secretion pathway protein E 853538..855031 Escherichia coli O104:H4 str. 2009EL-2050 13691394 YP_006768511.1 CDS O3M_04160 NC_018650.1 855031 856254 D COG1459 Type II secretory pathway, component PulF; General secretion pathway protein F 855031..856254 Escherichia coli O104:H4 str. 2009EL-2050 13691395 YP_006768512.1 CDS O3M_04165 NC_018650.1 856271 856726 D COG2165 Type II secretory pathway, pseudopilin PulG; general secretion pathway protein G 856271..856726 Escherichia coli O104:H4 str. 2009EL-2050 13691396 YP_006768513.1 CDS O3M_04170 NC_018650.1 856730 857293 D COG2165 Type II secretory pathway, pseudopilin PulG; general secretion pathway protein H 856730..857293 Escherichia coli O104:H4 str. 2009EL-2050 13691397 YP_006768514.1 CDS O3M_04175 NC_018650.1 857290 857661 D COG2165 Type II secretory pathway, pseudopilin PulG; type II secretion protein 857290..857661 Escherichia coli O104:H4 str. 2009EL-2050 13691398 YP_006768515.1 CDS O3M_04180 NC_018650.1 857658 858257 D COG4795 Type II secretory pathway, component PulJ; general secretion pathway protein J 857658..858257 Escherichia coli O104:H4 str. 2009EL-2050 13691399 YP_006768516.1 CDS O3M_04185 NC_018650.1 858260 859237 D COG3156 Type II secretory pathway, component PulK; type II secretion protein (GspK-like) 858260..859237 Escherichia coli O104:H4 str. 2009EL-2050 13691400 YP_006768517.1 CDS O3M_04190 NC_018650.1 859234 860412 D COG3297 Type II secretory pathway, component PulL; GspL-like protein 859234..860412 Escherichia coli O104:H4 str. 2009EL-2050 13691401 YP_006768518.1 CDS O3M_04195 NC_018650.1 860414 860950 D COG3149 Type II secretory pathway, component PulM; general secretion pathway protein YghD 860414..860950 Escherichia coli O104:H4 str. 2009EL-2050 13691402 YP_006768519.1 CDS O3M_04200 NC_018650.1 861231 862073 R hypothetical protein complement(861231..862073) Escherichia coli O104:H4 str. 2009EL-2050 13691403 YP_006768520.1 CDS O3M_04205 NC_018650.1 862158 862580 R hypothetical protein complement(862158..862580) Escherichia coli O104:H4 str. 2009EL-2050 13691404 YP_006768521.1 CDS O3M_04210 NC_018650.1 862577 862954 R toxin of the YeeV-YeeU toxin-antitoxin system complement(862577..862954) Escherichia coli O104:H4 str. 2009EL-2050 13691405 YP_006768522.1 CDS O3M_04215 NC_018650.1 863001 863378 R CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system complement(863001..863378) Escherichia coli O104:H4 str. 2009EL-2050 13691406 YP_006768523.1 CDS O3M_04220 NC_018650.1 863458 863679 R hypothetical protein complement(863458..863679) Escherichia coli O104:H4 str. 2009EL-2050 13691407 YP_006768524.1 CDS O3M_04225 NC_018650.1 863766 864242 R CP4-44 prophage; COG2003 DNA repair proteins; DNA repair protein complement(863766..864242) Escherichia coli O104:H4 str. 2009EL-2050 13691408 YP_006768525.1 CDS O3M_04230 NC_018650.1 864258 864731 R hypothetical protein complement(864258..864731) Escherichia coli O104:H4 str. 2009EL-2050 13691409 YP_006768526.1 CDS O3M_04235 NC_018650.1 865033 865851 R hypothetical protein complement(865033..865851) Escherichia coli O104:H4 str. 2009EL-2050 13691410 YP_006768527.1 CDS O3M_04240 NC_018650.1 865951 866184 R hypothetical protein complement(865951..866184) Escherichia coli O104:H4 str. 2009EL-2050 13691411 YP_006768528.1 CDS O3M_04245 NC_018650.1 866263 866718 R hypothetical protein complement(866263..866718) Escherichia coli O104:H4 str. 2009EL-2050 13691412 YP_006768529.1 CDS O3M_04250 NC_018650.1 866794 869310 R membrane protein, yeeR complement(866794..869310) Escherichia coli O104:H4 str. 2009EL-2050 13691413 YP_006768530.1 CDS O3M_04255 NC_018650.1 869431 872550 R COG2931 RTX toxins and related Ca2+-binding proteins; antigen 43 (Ag43) phase-variable biofilm formation autotransporter, CP4-44 prophage complement(869431..872550) Escherichia coli O104:H4 str. 2009EL-2050 13691414 YP_006768531.1 CDS O3M_04260 NC_018650.1 872884 873756 R COG3596 Predicted GTPase; GTPase complement(872884..873756) Escherichia coli O104:H4 str. 2009EL-2050 13691415 YP_006768532.1 CDS O3M_04265 NC_018650.1 873866 874885 R hypothetical protein complement(873866..874885) Escherichia coli O104:H4 str. 2009EL-2050 13691416 YP_006768533.1 CDS O3M_04270 NC_018650.1 875866 876054 D hypothetical protein 875866..876054 Escherichia coli O104:H4 str. 2009EL-2050 13691417 YP_006768534.1 CDS O3M_04275 NC_018650.1 876380 876952 R hypothetical protein complement(876380..876952) Escherichia coli O104:H4 str. 2009EL-2050 13691418 YP_006768535.1 CDS O3M_04280 NC_018650.1 877038 877244 R COG3311 Predicted transcriptional regulator; Prophage CP4-57 regulatory protein complement(877038..877244) Escherichia coli O104:H4 str. 2009EL-2050 13691419 YP_006768536.1 CDS O3M_04285 NC_018650.1 877943 878155 D hemolysin expression-modulating protein 877943..878155 Escherichia coli O104:H4 str. 2009EL-2050 13691420 YP_006768537.1 CDS O3M_04290 NC_018650.1 878772 879341 D hypothetical protein 878772..879341 Escherichia coli O104:H4 str. 2009EL-2050 13691421 YP_006768538.1 CDS O3M_04295 NC_018650.1 879509 879892 D hypothetical protein 879509..879892 Escherichia coli O104:H4 str. 2009EL-2050 13691422 YP_006768539.1 CDS O3M_04300 NC_018650.1 879882 880301 D hypothetical protein 879882..880301 Escherichia coli O104:H4 str. 2009EL-2050 13691423 YP_006768540.1 CDS O3M_04305 NC_018650.1 880307 880489 D hypothetical protein 880307..880489 Escherichia coli O104:H4 str. 2009EL-2050 13691424 YP_006768541.1 CDS O3M_04310 NC_018650.1 880610 881233 D hypothetical protein 880610..881233 Escherichia coli O104:H4 str. 2009EL-2050 13691425 YP_006768542.1 CDS O3M_04315 NC_018650.1 881329 881562 D hypothetical protein 881329..881562 Escherichia coli O104:H4 str. 2009EL-2050 13691426 YP_006768543.1 CDS O3M_04320 NC_018650.1 881615 881806 R hypothetical protein complement(881615..881806) Escherichia coli O104:H4 str. 2009EL-2050 13691427 YP_006768544.1 CDS O3M_04325 NC_018650.1 882313 882810 D COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 882313..882810 Escherichia coli O104:H4 str. 2009EL-2050 13691428 YP_006768545.1 CDS O3M_04330 NC_018650.1 882832 884193 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 882832..884193 Escherichia coli O104:H4 str. 2009EL-2050 13691429 YP_006768546.1 CDS O3M_04335 NC_018650.1 884295 885539 D hypothetical protein 884295..885539 Escherichia coli O104:H4 str. 2009EL-2050 13691430 YP_006768547.1 CDS O3M_04340 NC_018650.1 885856 887520 D COG0210 Superfamily I DNA and RNA helicases; UvrD/REP helicase 885856..887520 Escherichia coli O104:H4 str. 2009EL-2050 13691431 YP_006768548.1 CDS O3M_04345 NC_018650.1 887582 887890 D hypothetical protein 887582..887890 Escherichia coli O104:H4 str. 2009EL-2050 13691432 YP_006768549.1 CDS O3M_04350 NC_018650.1 887945 888172 D COG1475 Predicted transcriptional regulators; transcriptional regulator IbrB 887945..888172 Escherichia coli O104:H4 str. 2009EL-2050 13691433 YP_006768550.1 CDS O3M_04355 NC_018650.1 888251 888520 D transcriptional regulator 888251..888520 Escherichia coli O104:H4 str. 2009EL-2050 13691434 YP_006768551.1 CDS O3M_04360 NC_018650.1 888541 889185 D hypothetical protein 888541..889185 Escherichia coli O104:H4 str. 2009EL-2050 13691435 YP_006768552.1 CDS O3M_04365 NC_018650.1 889251 889574 D hypothetical protein 889251..889574 Escherichia coli O104:H4 str. 2009EL-2050 13691436 YP_006768553.1 CDS O3M_04370 NC_018650.1 889628 890023 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(889628..890023) Escherichia coli O104:H4 str. 2009EL-2050 13691437 YP_006768554.1 CDS O3M_04380 NC_018650.1 890394 890780 D hypothetical protein 890394..890780 Escherichia coli O104:H4 str. 2009EL-2050 13691438 YP_006768555.1 CDS O3M_04400 NC_018650.1 892301 892777 D COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 892301..892777 Escherichia coli O104:H4 str. 2009EL-2050 13691439 YP_006768556.1 CDS O3M_04405 NC_018650.1 892780 894258 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 892780..894258 Escherichia coli O104:H4 str. 2009EL-2050 13691440 YP_006768557.1 CDS O3M_04410 NC_018650.1 894268 894774 D hypothetical protein 894268..894774 Escherichia coli O104:H4 str. 2009EL-2050 13691441 YP_006768558.1 CDS O3M_04415 NC_018650.1 894784 895206 D hypothetical protein 894784..895206 Escherichia coli O104:H4 str. 2009EL-2050 13691442 YP_006768559.1 CDS O3M_04420 NC_018650.1 895242 895538 R hypothetical protein complement(895242..895538) Escherichia coli O104:H4 str. 2009EL-2050 13691443 YP_006768560.1 CDS O3M_04425 NC_018650.1 895670 897001 D COG3519 Uncharacterized protein conserved in bacteria; hypothetical protein 895670..897001 Escherichia coli O104:H4 str. 2009EL-2050 13691444 YP_006768561.1 CDS O3M_04430 NC_018650.1 896992 897924 D COG3520 Uncharacterized protein conserved in bacteria; hypothetical protein 896992..897924 Escherichia coli O104:H4 str. 2009EL-2050 13691445 YP_006768562.1 CDS O3M_04435 NC_018650.1 897937 899919 D COG3501 Uncharacterized protein conserved in bacteria; hypothetical protein 897937..899919 Escherichia coli O104:H4 str. 2009EL-2050 13691446 YP_006768563.1 CDS O3M_04440 NC_018650.1 899930 900397 D hypothetical protein 899930..900397 Escherichia coli O104:H4 str. 2009EL-2050 13691447 YP_006768564.1 CDS O3M_04445 NC_018650.1 900401 900706 D COG4104 Uncharacterized conserved protein; hypothetical protein 900401..900706 Escherichia coli O104:H4 str. 2009EL-2050 13691448 YP_006768565.1 CDS O3M_04450 NC_018650.1 900710 901786 D COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 900710..901786 Escherichia coli O104:H4 str. 2009EL-2050 13691449 YP_006768566.1 CDS O3M_04455 NC_018650.1 901794 902345 D hypothetical protein 901794..902345 Escherichia coli O104:H4 str. 2009EL-2050 13691450 YP_006768567.1 CDS O3M_04460 NC_018650.1 902364 903776 D COG3522 Uncharacterized protein conserved in bacteria; hypothetical protein 902364..903776 Escherichia coli O104:H4 str. 2009EL-2050 13691451 YP_006768568.1 CDS O3M_04465 NC_018650.1 903804 904118 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; hypothetical protein 903804..904118 Escherichia coli O104:H4 str. 2009EL-2050 13691452 YP_006768569.1 CDS O3M_04470 NC_018650.1 904115 904705 D COG3455 Uncharacterized protein conserved in bacteria; hypothetical protein 904115..904705 Escherichia coli O104:H4 str. 2009EL-2050 13691453 YP_006768570.1 CDS O3M_04475 NC_018650.1 904702 908115 D COG3523 Uncharacterized protein conserved in bacteria; hypothetical protein 904702..908115 Escherichia coli O104:H4 str. 2009EL-2050 13691454 YP_006768571.1 CDS O3M_04480 NC_018650.1 908119 910668 D COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 908119..910668 Escherichia coli O104:H4 str. 2009EL-2050 13691455 YP_006768572.1 CDS O3M_04490 NC_018650.1 911705 912076 D COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase 911705..912076 Escherichia coli O104:H4 str. 2009EL-2050 13691456 YP_006768573.1 CDS O3M_04495 NC_018650.1 913834 914400 D hypothetical protein 913834..914400 Escherichia coli O104:H4 str. 2009EL-2050 13691457 YP_006768574.1 CDS O3M_04500 NC_018650.1 914545 914778 R hypothetical protein complement(914545..914778) Escherichia coli O104:H4 str. 2009EL-2050 13691458 YP_006768575.1 CDS O3M_04505 NC_018650.1 914879 916033 D hypothetical protein 914879..916033 Escherichia coli O104:H4 str. 2009EL-2050 13691459 YP_006768576.1 CDS O3M_04510 NC_018650.1 916424 916825 D hypothetical protein 916424..916825 Escherichia coli O104:H4 str. 2009EL-2050 13691460 YP_006768577.1 CDS O3M_04515 NC_018650.1 917099 917284 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(917099..917284) Escherichia coli O104:H4 str. 2009EL-2050 13691461 YP_006768578.1 CDS O3M_04520 NC_018650.1 917348 918481 D COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 917348..918481 Escherichia coli O104:H4 str. 2009EL-2050 13691462 YP_006768579.1 CDS O3M_04525 NC_018650.1 918620 918883 D COG2801 Transposase and inactivated derivatives; IS150 ORF B; transposase 918620..918883 Escherichia coli O104:H4 str. 2009EL-2050 13691463 YP_006768580.1 CDS O3M_04530 NC_018650.1 919251 920231 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase complement(919251..920231) Escherichia coli O104:H4 str. 2009EL-2050 13691464 YP_006768581.1 CDS O3M_04535 NC_018650.1 920415 920978 R COG3436 Transposase and inactivated derivatives; transposase complement(920415..920978) Escherichia coli O104:H4 str. 2009EL-2050 13691465 YP_006768582.1 CDS O3M_04540 NC_018650.1 920875 921630 R COG4584 Transposase and inactivated derivatives; transposase complement(920875..921630) Escherichia coli O104:H4 str. 2009EL-2050 13691466 YP_006768583.1 CDS O3M_04545 NC_018650.1 921896 922000 R transposase complement(921896..922000) Escherichia coli O104:H4 str. 2009EL-2050 13691467 YP_006768584.1 CDS O3M_04550 NC_018650.1 922067 922201 R hypothetical protein complement(922067..922201) Escherichia coli O104:H4 str. 2009EL-2050 13691468 YP_006768585.1 CDS O3M_04555 NC_018650.1 922200 922730 D COG3436 Transposase and inactivated derivatives; hypothetical protein 922200..922730 Escherichia coli O104:H4 str. 2009EL-2050 13691469 YP_006768586.1 CDS O3M_04560 NC_018650.1 922793 923011 D COG3328 Transposase and inactivated derivatives; transposase 922793..923011 Escherichia coli O104:H4 str. 2009EL-2050 13691470 YP_006768587.1 CDS O3M_04565 NC_018650.1 923162 923497 R Serine protease pic precursor (ShMu) complement(923162..923497) Escherichia coli O104:H4 str. 2009EL-2050 13691471 YP_006768588.1 CDS O3M_04570 NC_018650.1 923499 927281 R COG3468 Type V secretory pathway, adhesin AidA; Serine protease pic precursor (ShMu) complement(923499..927281) Escherichia coli O104:H4 str. 2009EL-2050 13691472 YP_006768589.1 CDS O3M_04575 NC_018650.1 927446 927817 R COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase complement(927446..927817) Escherichia coli O104:H4 str. 2009EL-2050 13691473 YP_006768590.1 CDS O3M_04580 NC_018650.1 928009 929532 R COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid complement(928009..929532) Escherichia coli O104:H4 str. 2009EL-2050 13691474 YP_006768591.1 CDS O3M_04585 NC_018650.1 930124 930363 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(930124..930363) Escherichia coli O104:H4 str. 2009EL-2050 13691475 YP_006768592.1 CDS O3M_04590 NC_018650.1 930680 931831 D COG2826 Transposase and inactivated derivatives, IS30 family; transposase for IS30 930680..931831 Escherichia coli O104:H4 str. 2009EL-2050 13691476 YP_006768593.1 CDS O3M_04595 NC_018650.1 931751 932137 R COG2963 Transposase and inactivated derivatives; IS3 family protein; transposase ORF A, IS3 family protein complement(931751..932137) Escherichia coli O104:H4 str. 2009EL-2050 13691477 YP_006768594.1 CDS O3M_04600 NC_018650.1 932171 932464 R hypothetical protein complement(932171..932464) Escherichia coli O104:H4 str. 2009EL-2050 13691478 YP_006768595.1 CDS O3M_04605 NC_018650.1 932553 935423 R COG3421 Uncharacterized protein conserved in bacteria; PstII restriction-modification enzyme Res subunit complement(932553..935423) Escherichia coli O104:H4 str. 2009EL-2050 13691479 YP_006768596.1 CDS O3M_04610 NC_018650.1 935426 937054 R COG2189 Adenine specific DNA methylase Mod; DNA methylase N-4/N-6 complement(935426..937054) Escherichia coli O104:H4 str. 2009EL-2050 13691480 YP_006768597.1 CDS O3M_04615 NC_018650.1 937064 939451 R COG1404 Subtilisin-like serine proteases; serine protease complement(937064..939451) Escherichia coli O104:H4 str. 2009EL-2050 13691481 YP_006768598.1 CDS O3M_04620 NC_018650.1 939461 940441 R COG0464 ATPases of the AAA+ class; ATPase complement(939461..940441) Escherichia coli O104:H4 str. 2009EL-2050 13691482 YP_006768599.1 CDS O3M_04625 NC_018650.1 940467 943316 R COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Helicase complement(940467..943316) Escherichia coli O104:H4 str. 2009EL-2050 13691483 YP_006768600.1 CDS O3M_04630 NC_018650.1 943635 943799 D hypothetical protein 943635..943799 Escherichia coli O104:H4 str. 2009EL-2050 13691484 YP_006768601.1 CDS O3M_04635 NC_018650.1 943727 944320 D hypothetical protein 943727..944320 Escherichia coli O104:H4 str. 2009EL-2050 13691485 YP_006768602.1 CDS O3M_04640 NC_018650.1 944786 945049 R hypothetical protein complement(944786..945049) Escherichia coli O104:H4 str. 2009EL-2050 13691486 YP_006768603.1 CDS O3M_04645 NC_018650.1 945233 945694 R COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' complement(945233..945694) Escherichia coli O104:H4 str. 2009EL-2050 13691487 YP_006768604.1 CDS O3M_04650 NC_018650.1 945613 945888 R COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA complement(945613..945888) Escherichia coli O104:H4 str. 2009EL-2050 13691488 YP_006768605.1 CDS O3M_04655 NC_018650.1 946301 947563 R COG0582 Integrase; Prophage integrase complement(946301..947563) Escherichia coli O104:H4 str. 2009EL-2050 13691489 YP_006768606.1 CDS O3M_04660 NC_018650.1 947942 948649 R COG1811 Uncharacterized membrane protein, possible Na+ channel or pump; hypothetical protein complement(947942..948649) Escherichia coli O104:H4 str. 2009EL-2050 13691491 YP_006768607.1 CDS O3M_04665 NC_018650.1 949047 951182 D COG1982 Arginine/lysine/ornithine decarboxylases; ornithine decarboxylase 949047..951182 Escherichia coli O104:H4 str. 2009EL-2050 13691492 YP_006768608.1 CDS O3M_04670 NC_018650.1 951232 952488 R COG0477 Permeases of the major facilitator superfamily; nucleoside transport, permease complement(951232..952488) Escherichia coli O104:H4 str. 2009EL-2050 13691493 YP_006768609.1 CDS mltC NC_018650.1 952690 953769 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); murein transglycosylase C complement(952690..953769) Escherichia coli O104:H4 str. 2009EL-2050 13691494 YP_006768610.1 CDS O3M_04680 NC_018650.1 953834 954109 R COG2924 Fe-S cluster protector protein; oxidative damage protection protein complement(953834..954109) Escherichia coli O104:H4 str. 2009EL-2050 13691495 YP_006768611.1 CDS O3M_04685 NC_018650.1 954137 955189 R COG1194 A/G-specific DNA glycosylase; adenine DNA glycosylase complement(954137..955189) Escherichia coli O104:H4 str. 2009EL-2050 13691496 YP_006768612.1 CDS trmB NC_018650.1 955350 956069 D COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; tRNA (guanine-N(7)-)-methyltransferase 955350..956069 Escherichia coli O104:H4 str. 2009EL-2050 13691497 YP_006768613.1 CDS O3M_04695 NC_018650.1 956069 956395 D COG3171 Uncharacterized protein conserved in bacteria; hypothetical protein 956069..956395 Escherichia coli O104:H4 str. 2009EL-2050 13691498 YP_006768614.1 CDS O3M_04700 NC_018650.1 956418 956558 D hypothetical protein 956418..956558 Escherichia coli O104:H4 str. 2009EL-2050 13691499 YP_006768615.1 CDS O3M_04705 NC_018650.1 956579 957298 D hypothetical protein 956579..957298 Escherichia coli O104:H4 str. 2009EL-2050 13691500 YP_006768616.1 CDS ansB NC_018650.1 957474 958520 D COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; L-asparaginase II 957474..958520 Escherichia coli O104:H4 str. 2009EL-2050 13691501 YP_006768617.1 CDS O3M_04715 NC_018650.1 958637 959644 D hypothetical protein 958637..959644 Escherichia coli O104:H4 str. 2009EL-2050 13691502 YP_006768618.1 CDS O3M_04720 NC_018650.1 959799 960935 R COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; HemN family oxidoreductase complement(959799..960935) Escherichia coli O104:H4 str. 2009EL-2050 13691503 YP_006768619.1 CDS O3M_04725 NC_018650.1 960928 961521 R COG0127 Xanthosine triphosphate pyrophosphatase; dITP/XTP pyrophosphatase complement(960928..961521) Escherichia coli O104:H4 str. 2009EL-2050 13691504 YP_006768620.1 CDS O3M_04730 NC_018650.1 961529 961819 R COG1872 Uncharacterized conserved protein; hypothetical protein complement(961529..961819) Escherichia coli O104:H4 str. 2009EL-2050 13691505 YP_006768621.1 CDS O3M_04735 NC_018650.1 961816 962382 R COG0762 Predicted integral membrane protein; hypothetical protein complement(961816..962382) Escherichia coli O104:H4 str. 2009EL-2050 13691506 YP_006768622.1 CDS O3M_04740 NC_018650.1 962400 963104 R COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein complement(962400..963104) Escherichia coli O104:H4 str. 2009EL-2050 13691507 YP_006768623.1 CDS O3M_04745 NC_018650.1 963122 964102 D COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT; transporter 963122..964102 Escherichia coli O104:H4 str. 2009EL-2050 13691508 YP_006768624.1 CDS O3M_04750 NC_018650.1 964278 964694 R COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); Holliday junction resolvase-like protein complement(964278..964694) Escherichia coli O104:H4 str. 2009EL-2050 13691509 YP_006768625.1 CDS O3M_04755 NC_018650.1 964694 965257 R COG1678 Putative transcriptional regulator; hypothetical protein complement(964694..965257) Escherichia coli O104:H4 str. 2009EL-2050 13691510 YP_006768626.1 CDS O3M_04760 NC_018650.1 965366 966316 R COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); glutathione synthetase complement(965366..966316) Escherichia coli O104:H4 str. 2009EL-2050 13691511 YP_006768627.1 CDS O3M_04765 NC_018650.1 966329 967060 R COG1385 Uncharacterized protein conserved in bacteria; 16S ribosomal RNA methyltransferase RsmE complement(966329..967060) Escherichia coli O104:H4 str. 2009EL-2050 13691512 YP_006768628.1 CDS O3M_04770 NC_018650.1 967140 967847 R COG2356 Endonuclease I; DNA-specific endonuclease I complement(967140..967847) Escherichia coli O104:H4 str. 2009EL-2050 13691513 YP_006768629.1 CDS O3M_04775 NC_018650.1 967942 968439 R COG3091 Uncharacterized protein conserved in bacteria; hypothetical protein complement(967942..968439) Escherichia coli O104:H4 str. 2009EL-2050 13691595 YP_006768630.1 CDS O3M_04780 NC_018650.1 968516 969910 R COG0477 Permeases of the major facilitator superfamily; D-galactose transporter GalP complement(968516..969910) Escherichia coli O104:H4 str. 2009EL-2050 13691596 YP_006768631.1 CDS O3M_04785 NC_018650.1 970346 971500 R COG0192 S-adenosylmethionine synthetase; S-adenosylmethionine synthetase complement(970346..971500) Escherichia coli O104:H4 str. 2009EL-2050 13691597 YP_006768632.1 CDS O3M_04790 NC_018650.1 971556 971807 D hypothetical protein 971556..971807 Escherichia coli O104:H4 str. 2009EL-2050 13691598 YP_006768633.1 CDS O3M_04795 NC_018650.1 972140 972286 D hypothetical protein 972140..972286 Escherichia coli O104:H4 str. 2009EL-2050 13691599 YP_006768634.1 CDS O3M_04800 NC_018650.1 972295 974271 D COG1166 Arginine decarboxylase (spermidine biosynthesis); arginine decarboxylase 972295..974271 Escherichia coli O104:H4 str. 2009EL-2050 13691600 YP_006768635.1 CDS O3M_04805 NC_018650.1 974417 975148 D hypothetical protein 974417..975148 Escherichia coli O104:H4 str. 2009EL-2050 13691601 YP_006768636.1 CDS O3M_04810 NC_018650.1 975284 976204 D COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; agmatinase 975284..976204 Escherichia coli O104:H4 str. 2009EL-2050 13691602 YP_006768637.1 CDS O3M_04815 NC_018650.1 976410 977168 R COG0501 Zn-dependent protease with chaperone function; peptidase complement(976410..977168) Escherichia coli O104:H4 str. 2009EL-2050 13691603 YP_006768638.1 CDS O3M_04820 NC_018650.1 977446 979437 D COG0021 Transketolase; transketolase 977446..979437 Escherichia coli O104:H4 str. 2009EL-2050 13691604 YP_006768639.1 CDS cmtB NC_018650.1 979751 980194 D COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol-specific transporter subunit IIA 979751..980194 Escherichia coli O104:H4 str. 2009EL-2050 13691605 YP_006768640.1 CDS O3M_04830 NC_018650.1 980222 981610 D COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system mannitol-specific transporter subunit IIBC 980222..981610 Escherichia coli O104:H4 str. 2009EL-2050 13691606 YP_006768641.1 CDS O3M_04835 NC_018650.1 981625 982902 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; dehydrogenase 981625..982902 Escherichia coli O104:H4 str. 2009EL-2050 13691607 YP_006768642.1 CDS O3M_04840 NC_018650.1 982899 983864 D COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; fructose-1,6-bisphosphatase II-like protein 982899..983864 Escherichia coli O104:H4 str. 2009EL-2050 13691608 YP_006768643.1 CDS O3M_04845 NC_018650.1 983886 984395 D COG3722 Transcriptional regulator; DNA-binding transcriptional regulator 983886..984395 Escherichia coli O104:H4 str. 2009EL-2050 13691609 YP_006768644.1 CDS O3M_04850 NC_018650.1 984392 985105 D COG1072 Panthothenate kinase; nucleoside triphosphate hydrolase domain-containing protein 984392..985105 Escherichia coli O104:H4 str. 2009EL-2050 13691610 YP_006768645.1 CDS O3M_04855 NC_018650.1 985077 985754 R COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; ABC transporter ATP-binding protein complement(985077..985754) Escherichia coli O104:H4 str. 2009EL-2050 13691611 YP_006768646.1 CDS O3M_04860 NC_018650.1 985748 986425 R COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein complement(985748..986425) Escherichia coli O104:H4 str. 2009EL-2050 13691612 YP_006768647.1 CDS O3M_04865 NC_018650.1 986413 987120 R COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; lipoprotein complement(986413..987120) Escherichia coli O104:H4 str. 2009EL-2050 13691613 YP_006768648.1 CDS O3M_04870 NC_018650.1 987121 987699 R transporter complement(987121..987699) Escherichia coli O104:H4 str. 2009EL-2050 13691614 YP_006768649.1 CDS O3M_04875 NC_018650.1 987722 988153 R COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif; DNA-binding protein complement(987722..988153) Escherichia coli O104:H4 str. 2009EL-2050 13691615 YP_006768650.1 CDS O3M_04880 NC_018650.1 988525 989544 D COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; erythrose 4-phosphate dehydrogenase 988525..989544 Escherichia coli O104:H4 str. 2009EL-2050 13691616 YP_006768651.1 CDS pgk NC_018650.1 989594 990757 D COG0126 3-phosphoglycerate kinase; phosphoglycerate kinase 989594..990757 Escherichia coli O104:H4 str. 2009EL-2050 13691617 YP_006768652.1 CDS O3M_04890 NC_018650.1 990972 992051 D COG0191 Fructose/tagatose bisphosphate aldolase; fructose-bisphosphate aldolase 990972..992051 Escherichia coli O104:H4 str. 2009EL-2050 13691618 YP_006768653.1 CDS O3M_04895 NC_018650.1 992409 993269 D COG0668 Small-conductance mechanosensitive channel; mechanosensitive channel MscS 992409..993269 Escherichia coli O104:H4 str. 2009EL-2050 13691619 YP_006768654.1 CDS O3M_04900 NC_018650.1 993408 994043 D COG1279 Lysine efflux permease; arginine exporter protein 993408..994043 Escherichia coli O104:H4 str. 2009EL-2050 13691620 YP_006768655.1 CDS O3M_04905 NC_018650.1 994136 994876 D COG2968 Uncharacterized conserved protein; oxidative stress defense protein 994136..994876 Escherichia coli O104:H4 str. 2009EL-2050 13691621 YP_006768656.1 CDS O3M_04910 NC_018650.1 995043 995939 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 995043..995939 Escherichia coli O104:H4 str. 2009EL-2050 13691622 YP_006768657.1 CDS O3M_04915 NC_018650.1 995936 997414 R COG0427 Acetyl-CoA hydrolase; acetyl-CoA hydrolase complement(995936..997414) Escherichia coli O104:H4 str. 2009EL-2050 13691623 YP_006768658.1 CDS O3M_04920 NC_018650.1 997438 998223 R COG1024 Enoyl-CoA hydratase/carnithine racemase; methylmalonyl-CoA decarboxylase complement(997438..998223) Escherichia coli O104:H4 str. 2009EL-2050 13691624 YP_006768659.1 CDS O3M_04925 NC_018650.1 998234 999229 R COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family; membrane ATPase/protein kinase complement(998234..999229) Escherichia coli O104:H4 str. 2009EL-2050 13691625 YP_006768660.1 CDS O3M_04930 NC_018650.1 999222 1000514 R COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; methylmalonyl-CoA mutase complement(999222..1000514) Escherichia coli O104:H4 str. 2009EL-2050 13691626 YP_006768661.1 CDS O3M_04935 NC_018650.1 1000638 1001366 R COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; methylmalonyl-CoA mutase complement(1000638..1001366) Escherichia coli O104:H4 str. 2009EL-2050 13691627 YP_006768662.1 CDS O3M_04940 NC_018650.1 1001570 1002463 R COG0583 Transcriptional regulator; chromosome replication initiation inhibitor protein complement(1001570..1002463) Escherichia coli O104:H4 str. 2009EL-2050 13691628 YP_006768663.1 CDS O3M_04945 NC_018650.1 1002846 1003505 D COG0120 Ribose 5-phosphate isomerase; ribose-5-phosphate isomerase A 1002846..1003505 Escherichia coli O104:H4 str. 2009EL-2050 13691629 YP_006768664.1 CDS O3M_04950 NC_018650.1 1003761 1004993 D COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; D-3-phosphoglycerate dehydrogenase 1003761..1004993 Escherichia coli O104:H4 str. 2009EL-2050 13691630 YP_006768665.1 CDS O3M_04955 NC_018650.1 1005774 1006322 R COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase complement(1005774..1006322) Escherichia coli O104:H4 str. 2009EL-2050 13691631 YP_006768666.1 CDS O3M_04960 NC_018650.1 1006622 1006951 R COG3027 Uncharacterized protein conserved in bacteria; Z-ring-associated protein complement(1006622..1006951) Escherichia coli O104:H4 str. 2009EL-2050 13691632 YP_006768667.1 CDS O3M_04965 NC_018650.1 1007119 1007697 D COG3079 Uncharacterized protein conserved in bacteria; hypothetical protein 1007119..1007697 Escherichia coli O104:H4 str. 2009EL-2050 13691633 YP_006768668.1 CDS O3M_04970 NC_018650.1 1007723 1009048 D COG0006 Xaa-Pro aminopeptidase; proline aminopeptidase P II 1007723..1009048 Escherichia coli O104:H4 str. 2009EL-2050 13691634 YP_006768669.1 CDS O3M_04975 NC_018650.1 1009045 1010223 D COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 2-octaprenyl-6-methoxyphenyl hydroxylase 1009045..1010223 Escherichia coli O104:H4 str. 2009EL-2050 13691635 YP_006768670.1 CDS O3M_04980 NC_018650.1 1010246 1011448 D COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; oxidoreductase 1010246..1011448 Escherichia coli O104:H4 str. 2009EL-2050 13691636 YP_006768671.1 CDS gcvT NC_018650.1 1011896 1012990 D COG0404 Glycine cleavage system T protein (aminomethyltransferase); glycine cleavage system aminomethyltransferase T 1011896..1012990 Escherichia coli O104:H4 str. 2009EL-2050 13691637 YP_006768672.1 CDS O3M_04990 NC_018650.1 1013014 1013403 D COG0509 Glycine cleavage system H protein (lipoate-binding); glycine cleavage system protein H 1013014..1013403 Escherichia coli O104:H4 str. 2009EL-2050 13691638 YP_006768673.1 CDS O3M_04995 NC_018650.1 1013522 1016395 D COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; glycine dehydrogenase 1013522..1016395 Escherichia coli O104:H4 str. 2009EL-2050 13691639 YP_006768674.1 CDS O3M_05000 NC_018650.1 1016656 1017399 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); NAD(P)-binding oxidoreductase 1016656..1017399 Escherichia coli O104:H4 str. 2009EL-2050 13691640 YP_006768675.1 CDS O3M_05005 NC_018650.1 1017456 1018889 R COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; 6-phospho-beta-glucosidase complement(1017456..1018889) Escherichia coli O104:H4 str. 2009EL-2050 13691641 YP_006768676.1 CDS O3M_05010 NC_018650.1 1018934 1019245 D COG3097 Uncharacterized protein conserved in bacteria; hypothetical protein 1018934..1019245 Escherichia coli O104:H4 str. 2009EL-2050 13691642 YP_006768677.1 CDS O3M_05015 NC_018650.1 1019409 1020068 D COG1272 Predicted membrane protein, hemolysin III homolog; hemolysin 1019409..1020068 Escherichia coli O104:H4 str. 2009EL-2050 13691643 YP_006768678.1 CDS O3M_05020 NC_018650.1 1020146 1021126 R COG0354 Predicted aminomethyltransferase related to GcvT; global regulator complement(1020146..1021126) Escherichia coli O104:H4 str. 2009EL-2050 13691644 YP_006768679.1 CDS O3M_05025 NC_018650.1 1021369 1021635 D COG2938 Uncharacterized conserved protein; hypothetical protein 1021369..1021635 Escherichia coli O104:H4 str. 2009EL-2050 13691645 YP_006768680.1 CDS O3M_05030 NC_018650.1 1021616 1022023 D hypothetical protein 1021616..1022023 Escherichia coli O104:H4 str. 2009EL-2050 13691646 YP_006768681.1 CDS O3M_05035 NC_018650.1 1022063 1022584 R COG0716 Flavodoxins; flavodoxin FldB complement(1022063..1022584) Escherichia coli O104:H4 str. 2009EL-2050 13691647 YP_006768682.1 CDS xerD NC_018650.1 1022696 1023592 D COG4974 Site-specific recombinase XerD; site-specific tyrosine recombinase XerD 1022696..1023592 Escherichia coli O104:H4 str. 2009EL-2050 13691648 YP_006768683.1 CDS O3M_05045 NC_018650.1 1023617 1024327 D COG1651 Protein-disulfide isomerase; protein disulfide isomerase II DsbC 1023617..1024327 Escherichia coli O104:H4 str. 2009EL-2050 13691649 YP_006768684.1 CDS O3M_05050 NC_018650.1 1024333 1026066 D COG0608 Single-stranded DNA-specific exonuclease; ssDNA exonuclease RecJ 1024333..1026066 Escherichia coli O104:H4 str. 2009EL-2050 13691650 YP_006768685.1 CDS prfB NC_018650.1 1026374 1027255 D COG1186 Protein chain release factor B; peptide chain release factor 2 1026374..1027255 Escherichia coli O104:H4 str. 2009EL-2050 13691651 YP_006768686.1 CDS lysS NC_018650.1 1027265 1028782 D COG1190 Lysyl-tRNA synthetase (class II); lysyl-tRNA synthetase 1027265..1028782 Escherichia coli O104:H4 str. 2009EL-2050 13691652 YP_006768687.1 CDS O3M_05065 NC_018650.1 1028825 1029373 R COG1443 Isopentenyldiphosphate isomerase; isopentenyl-diphosphate delta-isomerase complement(1028825..1029373) Escherichia coli O104:H4 str. 2009EL-2050 13691653 YP_006768688.1 CDS O3M_05070 NC_018650.1 1029496 1029621 R hypothetical protein complement(1029496..1029621) Escherichia coli O104:H4 str. 2009EL-2050 13691654 YP_006768689.1 CDS O3M_05075 NC_018650.1 1029623 1031071 R COG2233 Xanthine/uracil permeases; transporter complement(1029623..1031071) Escherichia coli O104:H4 str. 2009EL-2050 13691655 YP_006768690.1 CDS O3M_05080 NC_018650.1 1031507 1033426 D COG1142 Fe-S-cluster-containing hydrogenase components 2; oxidoreductase Fe-S binding subunit 1031507..1033426 Escherichia coli O104:H4 str. 2009EL-2050 13691656 YP_006768691.1 CDS O3M_05085 NC_018650.1 1033426 1033914 D COG1142 Fe-S-cluster-containing hydrogenase components 2; oxidoreductase 1033426..1033914 Escherichia coli O104:H4 str. 2009EL-2050 13691657 YP_006768692.1 CDS O3M_05090 NC_018650.1 1033950 1035317 R COG2252 Permeases; hypothetical protein complement(1033950..1035317) Escherichia coli O104:H4 str. 2009EL-2050 13691658 YP_006768693.1 CDS O3M_05095 NC_018650.1 1035353 1036669 R COG0402 Cytosine deaminase and related metal-dependent hydrolases; guanine deaminase complement(1035353..1036669) Escherichia coli O104:H4 str. 2009EL-2050 13691659 YP_006768694.1 CDS O3M_05100 NC_018650.1 1036687 1038087 R COG2233 Xanthine/uracil permeases; transporter complement(1036687..1038087) Escherichia coli O104:H4 str. 2009EL-2050 13691660 YP_006768695.1 CDS O3M_05105 NC_018650.1 1038252 1041122 R COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; hypoxanthine oxidase complement(1038252..1041122) Escherichia coli O104:H4 str. 2009EL-2050 13691661 YP_006768696.1 CDS O3M_05110 NC_018650.1 1041119 1041898 R COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; oxidoreductase complement(1041119..1041898) Escherichia coli O104:H4 str. 2009EL-2050 13691662 YP_006768697.1 CDS O3M_05115 NC_018650.1 1041949 1043277 R COG0402 Cytosine deaminase and related metal-dependent hydrolases; chlorohydrolase/aminohydrolase complement(1041949..1043277) Escherichia coli O104:H4 str. 2009EL-2050 13691663 YP_006768698.1 CDS O3M_05120 NC_018650.1 1043280 1046378 R COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; selenate reductase subunit YgfK complement(1043280..1046378) Escherichia coli O104:H4 str. 2009EL-2050 13691664 YP_006768699.1 CDS O3M_05125 NC_018650.1 1046700 1047278 R COG2068 Uncharacterized MobA-related protein; hypothetical protein complement(1046700..1047278) Escherichia coli O104:H4 str. 2009EL-2050 13691665 YP_006768700.1 CDS O3M_05130 NC_018650.1 1047381 1048151 D COG0769 UDP-N-acetylmuramyl tripeptide synthase; hypothetical protein 1047381..1048151 Escherichia coli O104:H4 str. 2009EL-2050 13691666 YP_006768701.1 CDS O3M_05135 NC_018650.1 1048199 1049824 D COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 1048199..1049824 Escherichia coli O104:H4 str. 2009EL-2050 13691667 YP_006768702.1 CDS O3M_05140 NC_018650.1 1049865 1050797 R COG0549 Carbamate kinase; amino acid kinase complement(1049865..1050797) Escherichia coli O104:H4 str. 2009EL-2050 13691668 YP_006768703.1 CDS O3M_05145 NC_018650.1 1050845 1052230 R COG0044 Dihydroorotase and related cyclic amidohydrolases; phenylhydantoinase complement(1050845..1052230) Escherichia coli O104:H4 str. 2009EL-2050 13691669 YP_006768704.1 CDS O3M_05150 NC_018650.1 1052283 1053494 R COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; peptidase complement(1052283..1053494) Escherichia coli O104:H4 str. 2009EL-2050 13691670 YP_006768705.1 CDS O3M_05155 NC_018650.1 1053552 1054748 R COG1171 Threonine dehydratase; diaminopropionate ammonia-lyase complement(1053552..1054748) Escherichia coli O104:H4 str. 2009EL-2050 13691671 YP_006768706.1 CDS O3M_05160 NC_018650.1 1054806 1055993 R COG0078 Ornithine carbamoyltransferase; aspartate/ornithine carbamoyltransferase family protein complement(1054806..1055993) Escherichia coli O104:H4 str. 2009EL-2050 13691672 YP_006768707.1 CDS O3M_05165 NC_018650.1 1056472 1058250 D COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains; DNA-binding transcriptional regulator 1056472..1058250 Escherichia coli O104:H4 str. 2009EL-2050 13691673 YP_006768708.1 CDS O3M_05170 NC_018650.1 1058290 1058769 R COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; xanthine dehydrogenase subunit XdhC complement(1058290..1058769) Escherichia coli O104:H4 str. 2009EL-2050 13691674 YP_006768709.1 CDS O3M_05175 NC_018650.1 1058766 1059644 R COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; xanthine dehydrogenase subunit XdhB complement(1058766..1059644) Escherichia coli O104:H4 str. 2009EL-2050 13691675 YP_006768710.1 CDS O3M_05180 NC_018650.1 1059655 1061952 R COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; xanthine dehydrogenase subunit XdhA complement(1059655..1061952) Escherichia coli O104:H4 str. 2009EL-2050 13691757 YP_006768711.1 CDS O3M_05185 NC_018650.1 1062367 1063122 D COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 1062367..1063122 Escherichia coli O104:H4 str. 2009EL-2050 13691758 YP_006768712.1 CDS O3M_05190 NC_018650.1 1063466 1065118 D hypothetical protein 1063466..1065118 Escherichia coli O104:H4 str. 2009EL-2050 13691760 YP_006768713.1 CDS spaP NC_018650.1 1066187 1066852 D COG4790 Type III secretory pathway, component EscR; type III secretion system protein SpaP 1066187..1066852 Escherichia coli O104:H4 str. 2009EL-2050 13691761 YP_006768714.1 CDS O3M_05210 NC_018650.1 1066862 1067122 D COG4794 Type III secretory pathway, component EscS; type III secretion protein EpaQ 1066862..1067122 Escherichia coli O104:H4 str. 2009EL-2050 13691762 YP_006768715.1 CDS O3M_05215 NC_018650.1 1067124 1067891 D COG4791 Type III secretory pathway, component EscT; type III secretion apparatus protein SpaR/YscT/HrcT 1067124..1067891 Escherichia coli O104:H4 str. 2009EL-2050 13691763 YP_006768716.1 CDS O3M_05230 NC_018650.1 1068706 1069068 D COG1377 Flagellar biosynthesis pathway, component FlhB; type III secretion system protein SpaS 1068706..1069068 Escherichia coli O104:H4 str. 2009EL-2050 13691764 YP_006768717.1 CDS O3M_05235 NC_018650.1 1069130 1069423 R hypothetical protein complement(1069130..1069423) Escherichia coli O104:H4 str. 2009EL-2050 13691765 YP_006768718.1 CDS O3M_05240 NC_018650.1 1069425 1069925 R COG2771 DNA-binding HTH domain-containing proteins; response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain complement(1069425..1069925) Escherichia coli O104:H4 str. 2009EL-2050 13691766 YP_006768719.1 CDS O3M_05245 NC_018650.1 1070183 1071364 D type III secretion EprH protein 1070183..1071364 Escherichia coli O104:H4 str. 2009EL-2050 13691767 YP_006768720.1 CDS O3M_05250 NC_018650.1 1071378 1071533 D type III secretion protein EprI 1071378..1071533 Escherichia coli O104:H4 str. 2009EL-2050 13691768 YP_006768721.1 CDS O3M_05255 NC_018650.1 1071710 1071925 D type III secretion protein EprJ 1071710..1071925 Escherichia coli O104:H4 str. 2009EL-2050 13691769 YP_006768722.1 CDS O3M_05260 NC_018650.1 1071966 1072700 D COG4669 Type III secretory pathway, lipoprotein EscJ; type III secretion system lipoprotein EprK 1071966..1072700 Escherichia coli O104:H4 str. 2009EL-2050 13691770 YP_006768723.1 CDS O3M_05265 NC_018650.1 1072716 1073297 D hypothetical protein 1072716..1073297 Escherichia coli O104:H4 str. 2009EL-2050 13691771 YP_006768724.1 CDS O3M_05270 NC_018650.1 1073514 1073945 D hypothetical protein 1073514..1073945 Escherichia coli O104:H4 str. 2009EL-2050 13691772 YP_006768725.1 CDS O3M_05275 NC_018650.1 1074166 1074321 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 1074166..1074321 Escherichia coli O104:H4 str. 2009EL-2050 13691773 YP_006768726.1 CDS O3M_05280 NC_018650.1 1074355 1074798 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; hypothetical protein 1074355..1074798 Escherichia coli O104:H4 str. 2009EL-2050 13691774 YP_006768727.1 CDS O3M_05285 NC_018650.1 1074843 1075217 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); peptidoglycan-binding-like protein precursor complement(1074843..1075217) Escherichia coli O104:H4 str. 2009EL-2050 13691775 YP_006768728.1 CDS O3M_05290 NC_018650.1 1075402 1075620 R hypothetical protein complement(1075402..1075620) Escherichia coli O104:H4 str. 2009EL-2050 13691776 YP_006768729.1 CDS O3M_05295 NC_018650.1 1075788 1077164 R COG3710 DNA-binding winged-HTH domains; transcriptional regulator complement(1075788..1077164) Escherichia coli O104:H4 str. 2009EL-2050 13691777 YP_006768730.1 CDS O3M_05300 NC_018650.1 1077499 1077990 R COG0457 FOG: TPR repeat; chaperone complement(1077499..1077990) Escherichia coli O104:H4 str. 2009EL-2050 13691778 YP_006768731.1 CDS O3M_05305 NC_018650.1 1078268 1078705 R hypothetical protein complement(1078268..1078705) Escherichia coli O104:H4 str. 2009EL-2050 13691779 YP_006768732.1 CDS O3M_05310 NC_018650.1 1079360 1079440 D hypothetical protein 1079360..1079440 Escherichia coli O104:H4 str. 2009EL-2050 13691780 YP_006768733.1 CDS O3M_05315 NC_018650.1 1079473 1079955 R hypothetical protein complement(1079473..1079955) Escherichia coli O104:H4 str. 2009EL-2050 13691781 YP_006768734.1 CDS O3M_05320 NC_018650.1 1079948 1080757 R COG3710 DNA-binding winged-HTH domains; transcriptional regulator complement(1079948..1080757) Escherichia coli O104:H4 str. 2009EL-2050 13691782 YP_006768735.1 CDS O3M_05325 NC_018650.1 1081091 1081723 R bipartite regulator domain; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; yqeH protein complement(1081091..1081723) Escherichia coli O104:H4 str. 2009EL-2050 13691783 YP_006768736.1 CDS O3M_05330 NC_018650.1 1082183 1083412 R COG0814 Amino acid permeases; transporter protein complement(1082183..1083412) Escherichia coli O104:H4 str. 2009EL-2050 13691784 YP_006768737.1 CDS O3M_05335 NC_018650.1 1083667 1084848 D COG0183 Acetyl-CoA acetyltransferase; acyltransferase 1083667..1084848 Escherichia coli O104:H4 str. 2009EL-2050 13691785 YP_006768738.1 CDS O3M_05340 NC_018650.1 1085135 1085971 D COG3717 5-keto 4-deoxyuronate isomerase; 5-keto-4-deoxyuronate isomerase 1085135..1085971 Escherichia coli O104:H4 str. 2009EL-2050 13691786 YP_006768739.1 CDS O3M_05345 NC_018650.1 1086001 1086762 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2-deoxy-D-gluconate 3-dehydrogenase 1086001..1086762 Escherichia coli O104:H4 str. 2009EL-2050 13691787 YP_006768740.1 CDS O3M_05350 NC_018650.1 1087077 1088495 D COG0477 Permeases of the major facilitator superfamily; sugar transporter 1087077..1088495 Escherichia coli O104:H4 str. 2009EL-2050 13691788 YP_006768741.1 CDS O3M_05355 NC_018650.1 1088624 1089316 D COG1794 Aspartate racemase; racemase 1088624..1089316 Escherichia coli O104:H4 str. 2009EL-2050 13691789 YP_006768742.1 CDS O3M_05360 NC_018650.1 1089303 1090238 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator LysR complement(1089303..1090238) Escherichia coli O104:H4 str. 2009EL-2050 13691790 YP_006768743.1 CDS O3M_05365 NC_018650.1 1090360 1091622 D COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 1090360..1091622 Escherichia coli O104:H4 str. 2009EL-2050 13691791 YP_006768744.1 CDS O3M_05370 NC_018650.1 1091629 1092660 R COG1609 Transcriptional regulators; DNA-binding transcriptional regulator GalR complement(1091629..1092660) Escherichia coli O104:H4 str. 2009EL-2050 13691792 YP_006768745.1 CDS O3M_05375 NC_018650.1 1093246 1095405 D COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 1093246..1095405 Escherichia coli O104:H4 str. 2009EL-2050 13691793 YP_006768746.1 CDS O3M_05380 NC_018650.1 1095398 1096591 D COG0477 Permeases of the major facilitator superfamily; lysophospholipid transporter LplT 1095398..1096591 Escherichia coli O104:H4 str. 2009EL-2050 13691794 YP_006768747.1 CDS tas NC_018650.1 1096623 1097663 R COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo-keto reductase complement(1096623..1097663) Escherichia coli O104:H4 str. 2009EL-2050 13691795 YP_006768748.1 CDS O3M_05390 NC_018650.1 1097771 1097989 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; hypothetical protein complement(1097771..1097989) Escherichia coli O104:H4 str. 2009EL-2050 13691796 YP_006768749.1 CDS O3M_05395 NC_018650.1 1098127 1098840 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein complement(1098127..1098840) Escherichia coli O104:H4 str. 2009EL-2050 13691797 YP_006768750.1 CDS O3M_05400 NC_018650.1 1098909 1099598 R COG3066 DNA mismatch repair protein; DNA mismatch repair protein complement(1098909..1099598) Escherichia coli O104:H4 str. 2009EL-2050 13691798 YP_006768751.1 CDS O3M_05405 NC_018650.1 1100283 1100813 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; RNA pyrophosphohydrolase 1100283..1100813 Escherichia coli O104:H4 str. 2009EL-2050 13691799 YP_006768752.1 CDS O3M_05410 NC_018650.1 1100826 1103072 D fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; COG3605 Signal transduction protein containing GAF and PtsI domains; ptsP product 1100826..1103072 Escherichia coli O104:H4 str. 2009EL-2050 13691800 YP_006768753.1 CDS O3M_05415 NC_018650.1 1103223 1104098 D COG0682 Prolipoprotein diacylglyceryltransferase; prolipoprotein diacylglyceryl transferase 1103223..1104098 Escherichia coli O104:H4 str. 2009EL-2050 13691801 YP_006768754.1 CDS thyA NC_018650.1 1104105 1104899 D COG0207 Thymidylate synthase; thymidylate synthase 1104105..1104899 Escherichia coli O104:H4 str. 2009EL-2050 13691802 YP_006768755.1 CDS O3M_05425 NC_018650.1 1105084 1105554 D COG2165 Type II secretory pathway, pseudopilin PulG; hypothetical protein 1105084..1105554 Escherichia coli O104:H4 str. 2009EL-2050 13691803 YP_006768756.1 CDS O3M_05430 NC_018650.1 1105545 1106108 D COG4795 Type II secretory pathway, component PulJ; hypothetical protein 1105545..1106108 Escherichia coli O104:H4 str. 2009EL-2050 13691804 YP_006768757.1 CDS O3M_05435 NC_018650.1 1106105 1106512 D hypothetical protein 1106105..1106512 Escherichia coli O104:H4 str. 2009EL-2050 13691805 YP_006768758.1 CDS O3M_05440 NC_018650.1 1106497 1106820 D hypothetical protein 1106497..1106820 Escherichia coli O104:H4 str. 2009EL-2050 13691806 YP_006768759.1 CDS recC NC_018650.1 1106833 1110201 D COG1330 Exonuclease V gamma subunit; exonuclease V subunit gamma 1106833..1110201 Escherichia coli O104:H4 str. 2009EL-2050 13691807 YP_006768760.1 CDS O3M_05450 NC_018650.1 1110377 1113265 D COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; protease3 1110377..1113265 Escherichia coli O104:H4 str. 2009EL-2050 13691808 YP_006768761.1 CDS recB NC_018650.1 1113258 1116800 D COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); exonuclease V subunit beta 1113258..1116800 Escherichia coli O104:H4 str. 2009EL-2050 13691809 YP_006768762.1 CDS recD NC_018650.1 1116800 1118626 D COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; exonuclease V subunit alpha 1116800..1118626 Escherichia coli O104:H4 str. 2009EL-2050 13691810 YP_006768763.1 CDS O3M_05465 NC_018650.1 1118688 1120019 R COG0548 Acetylglutamate kinase; N-acetylglutamate synthase complement(1118688..1120019) Escherichia coli O104:H4 str. 2009EL-2050 13691811 YP_006768764.1 CDS O3M_05470 NC_018650.1 1120251 1121504 D COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 1120251..1121504 Escherichia coli O104:H4 str. 2009EL-2050 13691812 YP_006768765.1 CDS mltA NC_018650.1 1121863 1122960 D COG2821 Membrane-bound lytic murein transglycosylase; murein transglycosylase A 1121863..1122960 Escherichia coli O104:H4 str. 2009EL-2050 13691814 YP_006768766.1 CDS O3M_05480 NC_018650.1 1123037 1123843 D COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; sulfur acceptor protein CsdL 1123037..1123843 Escherichia coli O104:H4 str. 2009EL-2050 13691815 YP_006768767.1 CDS O3M_05485 NC_018650.1 1123894 1124337 R COG2166 SufE protein probably involved in Fe-S center assembly; CsdA-binding activator complement(1123894..1124337) Escherichia coli O104:H4 str. 2009EL-2050 13691816 YP_006768768.1 CDS O3M_05490 NC_018650.1 1124337 1125542 R COG0520 Selenocysteine lyase; cysteine sulfinate desulfinase complement(1124337..1125542) Escherichia coli O104:H4 str. 2009EL-2050 13691817 YP_006768769.1 CDS O3M_05495 NC_018650.1 1125734 1125961 D hypothetical protein 1125734..1125961 Escherichia coli O104:H4 str. 2009EL-2050 13691818 YP_006768770.1 CDS O3M_05500 NC_018650.1 1126312 1127229 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator GcvA 1126312..1127229 Escherichia coli O104:H4 str. 2009EL-2050 13691819 YP_006768771.1 CDS O3M_05505 NC_018650.1 1127248 1127643 D COG2363 Uncharacterized small membrane protein; hypothetical protein 1127248..1127643 Escherichia coli O104:H4 str. 2009EL-2050 13691820 YP_006768772.1 CDS O3M_05510 NC_018650.1 1127636 1128736 D COG2933 Predicted SAM-dependent methyltransferase; 23S rRNA C2498 ribose 2'-O-ribose methyltransferase 1127636..1128736 Escherichia coli O104:H4 str. 2009EL-2050 13691821 YP_006768773.1 CDS O3M_05515 NC_018650.1 1128780 1129511 R COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional activator FucR complement(1128780..1129511) Escherichia coli O104:H4 str. 2009EL-2050 13691822 YP_006768774.1 CDS fucU NC_018650.1 1129569 1129991 R COG4154 Fucose dissimilation pathway protein FucU; L-fucose mutarotase complement(1129569..1129991) Escherichia coli O104:H4 str. 2009EL-2050 13691823 YP_006768775.1 CDS O3M_05525 NC_018650.1 1129993 1131411 R COG1070 Sugar (pentulose and hexulose) kinases; L-fuculokinase complement(1129993..1131411) Escherichia coli O104:H4 str. 2009EL-2050 13691824 YP_006768776.1 CDS fucI NC_018650.1 1131520 1133295 R COG2407 L-fucose isomerase and related proteins; L-fucose isomerase complement(1131520..1133295) Escherichia coli O104:H4 str. 2009EL-2050 13691825 YP_006768777.1 CDS O3M_05535 NC_018650.1 1133328 1134644 R COG0738 Fucose permease; L-fucose transporter complement(1133328..1134644) Escherichia coli O104:H4 str. 2009EL-2050 13691826 YP_006768778.1 CDS O3M_05540 NC_018650.1 1135191 1135838 D COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-fuculose phosphate aldolase 1135191..1135838 Escherichia coli O104:H4 str. 2009EL-2050 13691827 YP_006768779.1 CDS O3M_05545 NC_018650.1 1135866 1137014 D COG1454 Alcohol dehydrogenase, class IV; L-1,2-propanediol oxidoreductase 1135866..1137014 Escherichia coli O104:H4 str. 2009EL-2050 13691828 YP_006768780.1 CDS O3M_05550 NC_018650.1 1137069 1137914 R COG0258 5'-3' exonuclease (including N-terminal domain of PolI); flap endonuclease-like protein complement(1137069..1137914) Escherichia coli O104:H4 str. 2009EL-2050 13691829 YP_006768781.1 CDS O3M_05555 NC_018650.1 1137936 1139303 R COG1760 L-serine deaminase; L-serine deaminase II complement(1137936..1139303) Escherichia coli O104:H4 str. 2009EL-2050 13691830 YP_006768782.1 CDS O3M_05560 NC_018650.1 1139361 1140650 R COG0814 Amino acid permeases; serine transporter complement(1139361..1140650) Escherichia coli O104:H4 str. 2009EL-2050 13691831 YP_006768783.1 CDS O3M_05565 NC_018650.1 1141207 1142571 R COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein complement(1141207..1142571) Escherichia coli O104:H4 str. 2009EL-2050 13691832 YP_006768784.1 CDS queF NC_018650.1 1142683 1143531 R COG2904 Uncharacterized protein conserved in bacteria; 7-cyano-7-deazaguanine reductase complement(1142683..1143531) Escherichia coli O104:H4 str. 2009EL-2050 13691833 YP_006768785.1 CDS O3M_05575 NC_018650.1 1143599 1144144 D SecY interacting protein Syd 1143599..1144144 Escherichia coli O104:H4 str. 2009EL-2050 13691834 YP_006768786.1 CDS O3M_05580 NC_018650.1 1144379 1144519 D hypothetical protein 1144379..1144519 Escherichia coli O104:H4 str. 2009EL-2050 13691835 YP_006768787.1 CDS O3M_05585 NC_018650.1 1144766 1145095 D COG3098 Uncharacterized protein conserved in bacteria; hypothetical protein 1144766..1145095 Escherichia coli O104:H4 str. 2009EL-2050 13691836 YP_006768788.1 CDS O3M_05600 NC_018650.1 1145895 1146344 D COG0716 Flavodoxins; flavodoxin 1145895..1146344 Escherichia coli O104:H4 str. 2009EL-2050 13691837 YP_006768789.1 CDS O3M_05605 NC_018650.1 1146779 1148131 D COG0477 Permeases of the major facilitator superfamily; D-glucarate transporter GudP 1146779..1148131 Escherichia coli O104:H4 str. 2009EL-2050 13691919 YP_006768790.1 CDS O3M_05620 NC_018650.1 1149494 1150834 D COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; (D)-glucarate dehydratase 1 1149494..1150834 Escherichia coli O104:H4 str. 2009EL-2050 13691920 YP_006768791.1 CDS O3M_05625 NC_018650.1 1151066 1153822 R COG0642 Signal transduction histidine kinase; hybrid sensory histidine kinase BarA complement(1151066..1153822) Escherichia coli O104:H4 str. 2009EL-2050 13691921 YP_006768792.1 CDS rumA NC_018650.1 1153879 1155180 D COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; 23S rRNA m(5)U1939 methyltransferase 1153879..1155180 Escherichia coli O104:H4 str. 2009EL-2050 13691922 YP_006768793.1 CDS relA NC_018650.1 1155228 1157462 D COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; (p)ppGpp synthetase I 1155228..1157462 Escherichia coli O104:H4 str. 2009EL-2050 13691923 YP_006768794.1 CDS O3M_05640 NC_018650.1 1157540 1157788 D COG2336 Growth regulator; antitoxin MazE 1157540..1157788 Escherichia coli O104:H4 str. 2009EL-2050 13691924 YP_006768795.1 CDS O3M_05645 NC_018650.1 1157788 1158123 D COG2337 Growth inhibitor; toxin MazF 1157788..1158123 Escherichia coli O104:H4 str. 2009EL-2050 13691925 YP_006768796.1 CDS mazG NC_018650.1 1158194 1158985 D COG1694 Predicted pyrophosphatase; nucleoside triphosphate pyrophosphohydrolase 1158194..1158985 Escherichia coli O104:H4 str. 2009EL-2050 13691926 YP_006768797.1 CDS pyrG NC_018650.1 1159213 1160850 D COG0504 CTP synthase (UTP-ammonia lyase); CTP synthetase 1159213..1160850 Escherichia coli O104:H4 str. 2009EL-2050 13691927 YP_006768798.1 CDS eno NC_018650.1 1160938 1162236 D COG0148 Enolase; enolase 1160938..1162236 Escherichia coli O104:H4 str. 2009EL-2050 13691928 YP_006768799.1 CDS O3M_05665 NC_018650.1 1162220 1162372 R hypothetical protein complement(1162220..1162372) Escherichia coli O104:H4 str. 2009EL-2050 13691929 YP_006768800.1 CDS O3M_05670 NC_018650.1 1162296 1163000 R COG1512 Beta-propeller domains of methanol dehydrogenase type; hypothetical protein complement(1162296..1163000) Escherichia coli O104:H4 str. 2009EL-2050 13691930 YP_006768801.1 CDS O3M_05675 NC_018650.1 1163182 1163322 R hypothetical protein complement(1163182..1163322) Escherichia coli O104:H4 str. 2009EL-2050 13691931 YP_006768802.1 CDS O3M_05680 NC_018650.1 1163461 1164132 D COG0602 Organic radical activating enzymes; hypothetical protein 1163461..1164132 Escherichia coli O104:H4 str. 2009EL-2050 13691932 YP_006768803.1 CDS O3M_05685 NC_018650.1 1164774 1164995 R hypothetical protein complement(1164774..1164995) Escherichia coli O104:H4 str. 2009EL-2050 13691933 YP_006768804.1 CDS O3M_05690 NC_018650.1 1165932 1167410 R COG1070 Sugar (pentulose and hexulose) kinases; kinase complement(1165932..1167410) Escherichia coli O104:H4 str. 2009EL-2050 13691934 YP_006768805.1 CDS O3M_05695 NC_018650.1 1167437 1168714 R COG0477 Permeases of the major facilitator superfamily; transporter complement(1167437..1168714) Escherichia coli O104:H4 str. 2009EL-2050 13691935 YP_006768806.1 CDS O3M_05700 NC_018650.1 1169033 1169818 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1169033..1169818 Escherichia coli O104:H4 str. 2009EL-2050 13691936 YP_006768807.1 CDS O3M_05705 NC_018650.1 1169888 1171342 D COG0277 FAD/FMN-containing dehydrogenases; FAD containing dehydrogenase 1169888..1171342 Escherichia coli O104:H4 str. 2009EL-2050 13691937 YP_006768808.1 CDS O3M_05710 NC_018650.1 1171436 1172773 D COG0477 Permeases of the major facilitator superfamily; transporter 1171436..1172773 Escherichia coli O104:H4 str. 2009EL-2050 13691938 YP_006768809.1 CDS O3M_05715 NC_018650.1 1172751 1173530 D COG2086 Electron transfer flavoprotein, beta subunit; electron transfer flavoprotein 1172751..1173530 Escherichia coli O104:H4 str. 2009EL-2050 13691939 YP_006768810.1 CDS O3M_05720 NC_018650.1 1173527 1174387 D COG2025 Electron transfer flavoprotein, alpha subunit; flavoprotein 1173527..1174387 Escherichia coli O104:H4 str. 2009EL-2050 13691940 YP_006768811.1 CDS O3M_05725 NC_018650.1 1174535 1175110 R COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding); anti-terminator regulatory protein complement(1174535..1175110) Escherichia coli O104:H4 str. 2009EL-2050 13691941 YP_006768812.1 CDS O3M_05730 NC_018650.1 1175127 1175387 R COG2440 Ferredoxin-like protein; 4Fe-4S binding protein complement(1175127..1175387) Escherichia coli O104:H4 str. 2009EL-2050 13691942 YP_006768813.1 CDS O3M_05735 NC_018650.1 1175378 1176649 R COG0644 Dehydrogenases (flavoproteins); oxidoreductase with FAD/NAD(P)-binding domain complement(1175378..1176649) Escherichia coli O104:H4 str. 2009EL-2050 13691943 YP_006768814.1 CDS O3M_05740 NC_018650.1 1176727 1177089 R COG0720 6-pyruvoyl-tetrahydropterin synthase; 6-pyruvoyl tetrahydrobiopterin synthase complement(1176727..1177089) Escherichia coli O104:H4 str. 2009EL-2050 13691944 YP_006768815.1 CDS cysJ NC_018650.1 1177408 1179207 D COG0369 Sulfite reductase, alpha subunit (flavoprotein); sulfite reductase subunit alpha 1177408..1179207 Escherichia coli O104:H4 str. 2009EL-2050 13691945 YP_006768816.1 CDS O3M_05750 NC_018650.1 1179207 1180919 D COG0155 Sulfite reductase, beta subunit (hemoprotein); sulfite reductase subunit beta 1179207..1180919 Escherichia coli O104:H4 str. 2009EL-2050 13691946 YP_006768817.1 CDS O3M_05755 NC_018650.1 1180993 1181727 D COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; phosphoadenosine phosphosulfate reductase 1180993..1181727 Escherichia coli O104:H4 str. 2009EL-2050 13691947 YP_006768818.1 CDS O3M_05760 NC_018650.1 1181992 1182144 D small toxic membrane polypeptide 1181992..1182144 Escherichia coli O104:H4 str. 2009EL-2050 13691948 YP_006768819.1 CDS O3M_05765 NC_018650.1 1182221 1183333 D COG3385 FOG: Transposase and inactivated derivatives; transposase insL for insertion sequence IS186 1182221..1183333 Escherichia coli O104:H4 str. 2009EL-2050 13691949 YP_006768820.1 CDS O3M_05770 NC_018650.1 1183729 1186386 D COG1203 Predicted helicases; hypothetical protein 1183729..1186386 Escherichia coli O104:H4 str. 2009EL-2050 13691950 YP_006768821.1 CDS O3M_05775 NC_018650.1 1186484 1188046 D hypothetical protein 1186484..1188046 Escherichia coli O104:H4 str. 2009EL-2050 13691951 YP_006768822.1 CDS O3M_05780 NC_018650.1 1188043 1188579 D hypothetical protein 1188043..1188579 Escherichia coli O104:H4 str. 2009EL-2050 13691952 YP_006768823.1 CDS O3M_05785 NC_018650.1 1188591 1189646 D hypothetical protein 1188591..1189646 Escherichia coli O104:H4 str. 2009EL-2050 13691953 YP_006768824.1 CDS O3M_05790 NC_018650.1 1189657 1190403 D hypothetical protein 1189657..1190403 Escherichia coli O104:H4 str. 2009EL-2050 13691954 YP_006768825.1 CDS O3M_05795 NC_018650.1 1190385 1191035 D hypothetical protein 1190385..1191035 Escherichia coli O104:H4 str. 2009EL-2050 13691955 YP_006768826.1 CDS O3M_05800 NC_018650.1 1191032 1191952 D COG1518 Uncharacterized protein predicted to be involved in DNA repair; CRISPR-associated protein Cas1 1191032..1191952 Escherichia coli O104:H4 str. 2009EL-2050 13691956 YP_006768827.1 CDS O3M_05805 NC_018650.1 1191952 1192245 D ssRNA endonuclease 1191952..1192245 Escherichia coli O104:H4 str. 2009EL-2050 13691957 YP_006768828.1 CDS O3M_05810 NC_018650.1 1192513 1193550 R COG2234 Predicted aminopeptidases; alkaline phosphatase isozyme conversion aminopeptidase complement(1192513..1193550) Escherichia coli O104:H4 str. 2009EL-2050 13691958 YP_006768829.1 CDS O3M_05815 NC_018650.1 1193802 1194710 D COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; sulfate adenylyltransferase subunit 2 1193802..1194710 Escherichia coli O104:H4 str. 2009EL-2050 13691959 YP_006768830.1 CDS cysN NC_018650.1 1194712 1196139 D COG2895 GTPases - Sulfate adenylate transferase subunit 1; sulfate adenylyltransferase subunit 1 1194712..1196139 Escherichia coli O104:H4 str. 2009EL-2050 13691960 YP_006768831.1 CDS O3M_05825 NC_018650.1 1196139 1196744 D COG0529 Adenylylsulfate kinase and related kinases; adenylylsulfate kinase 1196139..1196744 Escherichia coli O104:H4 str. 2009EL-2050 13691961 YP_006768832.1 CDS O3M_05830 NC_018650.1 1196794 1197117 D COG0665 Glycine/D-amino acid oxidases (deaminating); hypothetical protein 1196794..1197117 Escherichia coli O104:H4 str. 2009EL-2050 13691962 YP_006768833.1 CDS ftsB NC_018650.1 1197311 1197622 D COG2919 Septum formation initiator; cell division protein FtsB 1197311..1197622 Escherichia coli O104:H4 str. 2009EL-2050 13691963 YP_006768834.1 CDS ispD NC_018650.1 1197641 1198351 D COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1197641..1198351 Escherichia coli O104:H4 str. 2009EL-2050 13691964 YP_006768835.1 CDS ispF NC_018650.1 1198351 1198830 D COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 1198351..1198830 Escherichia coli O104:H4 str. 2009EL-2050 13691965 YP_006768836.1 CDS truD NC_018650.1 1198827 1199876 D COG0585 Uncharacterized conserved protein; tRNA pseudouridine synthase D 1198827..1199876 Escherichia coli O104:H4 str. 2009EL-2050 13691966 YP_006768837.1 CDS surE NC_018650.1 1199857 1200618 D COG0496 Predicted acid phosphatase; 5'(3')-nucleotidase/polyphosphatase 1199857..1200618 Escherichia coli O104:H4 str. 2009EL-2050 13691967 YP_006768838.1 CDS pcm NC_018650.1 1200612 1201238 D COG2518 Protein-L-isoaspartate carboxylmethyltransferase; protein-L-isoaspartate O-methyltransferase 1200612..1201238 Escherichia coli O104:H4 str. 2009EL-2050 13691968 YP_006768839.1 CDS nlpD NC_018650.1 1201378 1202517 D COG0739 Membrane proteins related to metalloendopeptidases; lipoprotein NlpD 1201378..1202517 Escherichia coli O104:H4 str. 2009EL-2050 13691969 YP_006768840.1 CDS O3M_05870 NC_018650.1 1202580 1203572 D COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor RpoS 1202580..1203572 Escherichia coli O104:H4 str. 2009EL-2050 13691970 YP_006768841.1 CDS O3M_05875 NC_018650.1 1203693 1204100 R COG1846 Transcriptional regulators; transcriptional regulator hosA complement(1203693..1204100) Escherichia coli O104:H4 str. 2009EL-2050 13691971 YP_006768842.1 CDS O3M_05880 NC_018650.1 1204247 1204840 D COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; phenylacrylic acid decarboxylase 1204247..1204840 Escherichia coli O104:H4 str. 2009EL-2050 13691972 YP_006768843.1 CDS O3M_05885 NC_018650.1 1204840 1206267 D COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; 4-hydroxybenzoate decarboxylase 1204840..1206267 Escherichia coli O104:H4 str. 2009EL-2050 13691973 YP_006768844.1 CDS O3M_05890 NC_018650.1 1206278 1206514 D non-oxidative reversible hydroxyarylic acid decarboxylase 1206278..1206514 Escherichia coli O104:H4 str. 2009EL-2050 13691974 YP_006768845.1 CDS O3M_05895 NC_018650.1 1206554 1207918 R COG2610 H+/gluconate symporter and related permeases; transporter complement(1206554..1207918) Escherichia coli O104:H4 str. 2009EL-2050 13691975 YP_006768846.1 CDS O3M_05900 NC_018650.1 1208007 1208783 R COG3622 Hydroxypyruvate isomerase; hypothetical protein complement(1208007..1208783) Escherichia coli O104:H4 str. 2009EL-2050 13691976 YP_006768847.1 CDS O3M_05905 NC_018650.1 1208788 1209426 R COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; aldolase complement(1208788..1209426) Escherichia coli O104:H4 str. 2009EL-2050 13691977 YP_006768848.1 CDS O3M_05910 NC_018650.1 1209423 1210685 R COG3395 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1209423..1210685) Escherichia coli O104:H4 str. 2009EL-2050 13691978 YP_006768849.1 CDS O3M_05915 NC_018650.1 1210682 1211590 R COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; dehydrogenase complement(1210682..1211590) Escherichia coli O104:H4 str. 2009EL-2050 13691979 YP_006768850.1 CDS O3M_05920 NC_018650.1 1211786 1212553 D COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 1211786..1212553 Escherichia coli O104:H4 str. 2009EL-2050 13691980 YP_006768851.1 CDS O3M_05925 NC_018650.1 1212604 1213260 R COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; serine/threonine-specific protein phosphatase 2 complement(1212604..1213260) Escherichia coli O104:H4 str. 2009EL-2050 13691981 YP_006768852.1 CDS O3M_05930 NC_018650.1 1213366 1215927 R COG0249 Mismatch repair ATPase (MutS family); DNA mismatch repair protein MutS complement(1213366..1215927) Escherichia coli O104:H4 str. 2009EL-2050 13691982 YP_006768853.1 CDS O3M_05935 NC_018650.1 1216003 1216182 D hypothetical protein 1216003..1216182 Escherichia coli O104:H4 str. 2009EL-2050 13691983 YP_006768854.1 CDS O3M_05940 NC_018650.1 1216214 1216567 D hypothetical protein 1216214..1216567 Escherichia coli O104:H4 str. 2009EL-2050 13691984 YP_006768855.1 CDS O3M_05945 NC_018650.1 1216604 1218682 R COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; formate hydrogenlyase transcriptional activator FhlA complement(1216604..1218682) Escherichia coli O104:H4 str. 2009EL-2050 13691985 YP_006768856.1 CDS O3M_05950 NC_018650.1 1218756 1219766 R COG0309 Hydrogenase maturation factor; hydrogenase expression/formation protein HypE complement(1218756..1219766) Escherichia coli O104:H4 str. 2009EL-2050 13691986 YP_006768857.1 CDS O3M_05955 NC_018650.1 1219763 1220884 R COG0409 Hydrogenase maturation factor; hydrogenase expression/formation protein HypD complement(1219763..1220884) Escherichia coli O104:H4 str. 2009EL-2050 13691987 YP_006768858.1 CDS O3M_05960 NC_018650.1 1220884 1221156 R COG0298 Hydrogenase maturation factor; hydrogenase assembly chaperone complement(1220884..1221156) Escherichia coli O104:H4 str. 2009EL-2050 13691988 YP_006768859.1 CDS O3M_05965 NC_018650.1 1221147 1222019 R COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; hydrogenase nickel incorporation protein HypB complement(1221147..1222019) Escherichia coli O104:H4 str. 2009EL-2050 13692070 YP_006768860.1 CDS hypA NC_018650.1 1222023 1222373 R COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); hydrogenase nickel incorporation protein complement(1222023..1222373) Escherichia coli O104:H4 str. 2009EL-2050 13692071 YP_006768861.1 CDS O3M_05975 NC_018650.1 1222584 1223045 D formate hydrogenlyase regulatory protein HycA 1222584..1223045 Escherichia coli O104:H4 str. 2009EL-2050 13692072 YP_006768862.1 CDS O3M_05980 NC_018650.1 1222961 1223269 R hypothetical protein complement(1222961..1223269) Escherichia coli O104:H4 str. 2009EL-2050 13692073 YP_006768863.1 CDS O3M_05985 NC_018650.1 1223170 1223781 D COG1142 Fe-S-cluster-containing hydrogenase components 2; formate hydrogenlyase subunit B 1223170..1223781 Escherichia coli O104:H4 str. 2009EL-2050 13692074 YP_006768864.1 CDS O3M_05990 NC_018650.1 1223778 1225604 D COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; formate hydrogenlyase subunit 3 1223778..1225604 Escherichia coli O104:H4 str. 2009EL-2050 13692075 YP_006768865.1 CDS O3M_05995 NC_018650.1 1225607 1226530 D COG0650 Formate hydrogenlyase subunit 4; hydrogenase 3, membrane subunit HycD 1225607..1226530 Escherichia coli O104:H4 str. 2009EL-2050 13692076 YP_006768866.1 CDS O3M_06000 NC_018650.1 1226548 1228257 D COG3262 Ni,Fe-hydrogenase III component G; formate hydrogenlyase subunit E 1226548..1228257 Escherichia coli O104:H4 str. 2009EL-2050 13692077 YP_006768867.1 CDS O3M_06005 NC_018650.1 1228267 1228809 D COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); formate hydrogenlyase complex iron-sulfur subunit 1228267..1228809 Escherichia coli O104:H4 str. 2009EL-2050 13692078 YP_006768868.1 CDS O3M_06010 NC_018650.1 1228809 1229576 D COG3260 Ni,Fe-hydrogenase III small subunit; hydrogenase 3 and formate hydrogenase complex, HycG subunit 1228809..1229576 Escherichia coli O104:H4 str. 2009EL-2050 13692079 YP_006768869.1 CDS O3M_06015 NC_018650.1 1229573 1229983 D formate hydrogenlyase maturation protein HycH 1229573..1229983 Escherichia coli O104:H4 str. 2009EL-2050 13692080 YP_006768870.1 CDS hycI NC_018650.1 1229976 1230446 D COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 3 maturation protease 1229976..1230446 Escherichia coli O104:H4 str. 2009EL-2050 13692081 YP_006768871.1 CDS O3M_06025 NC_018650.1 1230471 1231244 D hypothetical protein 1230471..1231244 Escherichia coli O104:H4 str. 2009EL-2050 13692082 YP_006768872.1 CDS O3M_06030 NC_018650.1 1231315 1231734 D COG5499 Predicted transcription regulator containing HTH domain; HTH-type transcriptional regulator ygjM 1231315..1231734 Escherichia coli O104:H4 str. 2009EL-2050 13692083 YP_006768873.1 CDS O3M_06035 NC_018650.1 1231979 1232959 D COG3547 Transposase and inactivated derivatives; IS621 transposase 1231979..1232959 Escherichia coli O104:H4 str. 2009EL-2050 13692084 YP_006768874.1 CDS O3M_06040 NC_018650.1 1233127 1234551 R COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; cryptic 6-phospho-beta-glucosidase complement(1233127..1234551) Escherichia coli O104:H4 str. 2009EL-2050 13692085 YP_006768875.1 CDS O3M_06045 NC_018650.1 1234560 1236017 R COG1264 Phosphotransferase system IIB components; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC complement(1234560..1236017) Escherichia coli O104:H4 str. 2009EL-2050 13692086 YP_006768876.1 CDS O3M_06050 NC_018650.1 1236274 1237287 D COG1609 Transcriptional regulators; transcriptional regulator 1236274..1237287 Escherichia coli O104:H4 str. 2009EL-2050 13692087 YP_006768877.1 CDS O3M_06055 NC_018650.1 1237436 1237963 D COG1142 Fe-S-cluster-containing hydrogenase components 2; formate dehydrogenase-H ferredoxin subunit 1237436..1237963 Escherichia coli O104:H4 str. 2009EL-2050 13692088 YP_006768878.1 CDS O3M_06060 NC_018650.1 1238116 1240368 D COG0068 Hydrogenase maturation factor; hydrogenase maturation protein 1238116..1240368 Escherichia coli O104:H4 str. 2009EL-2050 13692089 YP_006768879.1 CDS O3M_06065 NC_018650.1 1240594 1241727 R COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; NADH:flavorubredoxin oxidoreductase complement(1240594..1241727) Escherichia coli O104:H4 str. 2009EL-2050 13692090 YP_006768880.1 CDS O3M_06070 NC_018650.1 1241724 1243163 R COG0426 Uncharacterized flavoproteins; anaerobic nitric oxide reductase flavorubredoxin complement(1241724..1243163) Escherichia coli O104:H4 str. 2009EL-2050 13692091 YP_006768881.1 CDS O3M_06075 NC_018650.1 1243350 1244864 D COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; anaerobic nitric oxide reductase transcriptional regulator 1243350..1244864 Escherichia coli O104:H4 str. 2009EL-2050 13692092 YP_006768882.1 CDS gutQ NC_018650.1 1244861 1245826 R COG0794 Predicted sugar phosphate isomerase involved in capsule formation; D-arabinose 5-phosphate isomerase complement(1244861..1245826) Escherichia coli O104:H4 str. 2009EL-2050 13692093 YP_006768883.1 CDS srlR NC_018650.1 1245819 1246592 R COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor SrlR complement(1245819..1246592) Escherichia coli O104:H4 str. 2009EL-2050 13692094 YP_006768884.1 CDS O3M_06090 NC_018650.1 1246659 1247018 R COG4578 Glucitol operon activator; DNA-binding transcriptional activator GutM complement(1246659..1247018) Escherichia coli O104:H4 str. 2009EL-2050 13692095 YP_006768885.1 CDS O3M_06095 NC_018650.1 1247123 1247902 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); sorbitol-6-phosphate dehydrogenase complement(1247123..1247902) Escherichia coli O104:H4 str. 2009EL-2050 13692096 YP_006768886.1 CDS O3M_06100 NC_018650.1 1247906 1248277 R COG3731 Phosphotransferase system sorbitol-specific component IIA; PTS system glucitol/sorbitol-specific transporter subunit IIA complement(1247906..1248277) Escherichia coli O104:H4 str. 2009EL-2050 13692097 YP_006768887.1 CDS O3M_06105 NC_018650.1 1248288 1249247 R COG3732 Phosphotransferase system sorbitol-specific component IIBC; PTS system glucitol/sorbitol-specific transporter subunit IIB complement(1248288..1249247) Escherichia coli O104:H4 str. 2009EL-2050 13692098 YP_006768888.1 CDS O3M_06110 NC_018650.1 1249244 1249807 R COG3730 Phosphotransferase system sorbitol-specific component IIC; glucitol/sorbitol permease IIC component complement(1249244..1249807) Escherichia coli O104:H4 str. 2009EL-2050 13692099 YP_006768889.1 CDS O3M_06115 NC_018650.1 1250063 1251148 D COG2951 Membrane-bound lytic murein transglycosylase B; murein hydrolase B 1250063..1251148 Escherichia coli O104:H4 str. 2009EL-2050 13692100 YP_006768890.1 CDS O3M_06120 NC_018650.1 1251293 1251790 D COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein 1251293..1251790 Escherichia coli O104:H4 str. 2009EL-2050 13692101 YP_006768891.1 CDS recA NC_018650.1 1251870 1252931 D COG0468 RecA/RadA recombinase; recombinase A 1251870..1252931 Escherichia coli O104:H4 str. 2009EL-2050 13692102 YP_006768892.1 CDS recX NC_018650.1 1253174 1253674 D COG2137 Uncharacterized protein conserved in bacteria; recombination regulator RecX 1253174..1253674 Escherichia coli O104:H4 str. 2009EL-2050 13692103 YP_006768893.1 CDS O3M_06135 NC_018650.1 1253715 1253864 R hypothetical protein complement(1253715..1253864) Escherichia coli O104:H4 str. 2009EL-2050 13692104 YP_006768894.1 CDS alaS NC_018650.1 1253802 1256432 D COG0013 Alanyl-tRNA synthetase; alanyl-tRNA synthetase 1253802..1256432 Escherichia coli O104:H4 str. 2009EL-2050 13692105 YP_006768895.1 CDS O3M_06145 NC_018650.1 1256667 1256852 D COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); carbon storage regulator 1256667..1256852 Escherichia coli O104:H4 str. 2009EL-2050 13692106 YP_006768896.1 CDS O3M_06150 NC_018650.1 1258444 1259010 D COG0637 Predicted phosphatase/phosphohexomutase; fructose-1-P/6-phosphogluconate phosphatase 1258444..1259010 Escherichia coli O104:H4 str. 2009EL-2050 13692112 YP_006768897.1 CDS O3M_06155 NC_018650.1 1259007 1259435 D COG1238 Predicted membrane protein; hypothetical protein 1259007..1259435 Escherichia coli O104:H4 str. 2009EL-2050 13692113 YP_006768898.1 CDS O3M_06160 NC_018650.1 1259508 1261064 D COG2918 Gamma-glutamylcysteine synthetase; glutamate--cysteine ligase 1259508..1261064 Escherichia coli O104:H4 str. 2009EL-2050 13692114 YP_006768899.1 CDS O3M_06165 NC_018650.1 1261214 1261729 D COG1854 LuxS protein involved in autoinducer AI2 synthesis; S-ribosylhomocysteinase 1261214..1261729 Escherichia coli O104:H4 str. 2009EL-2050 13692115 YP_006768900.1 CDS O3M_06170 NC_018650.1 1261793 1263331 R COG0477 Permeases of the major facilitator superfamily; membrane translocase complement(1261793..1263331) Escherichia coli O104:H4 str. 2009EL-2050 13692116 YP_006768901.1 CDS O3M_06175 NC_018650.1 1263348 1264520 R COG1566 Multidrug resistance efflux pump; multidrug efflux system protein EmrA complement(1263348..1264520) Escherichia coli O104:H4 str. 2009EL-2050 13692117 YP_006768902.1 CDS O3M_06180 NC_018650.1 1264647 1265177 R COG1846 Transcriptional regulators; transcriptional repressor MprA complement(1264647..1265177) Escherichia coli O104:H4 str. 2009EL-2050 13692118 YP_006768903.1 CDS O3M_06185 NC_018650.1 1265268 1265603 R L-valine exporter complement(1265268..1265603) Escherichia coli O104:H4 str. 2009EL-2050 13692119 YP_006768904.1 CDS O3M_06190 NC_018650.1 1265593 1266330 R COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); branched chain amino acid exporter (LIV-E) family protein complement(1265593..1266330) Escherichia coli O104:H4 str. 2009EL-2050 13692120 YP_006768905.1 CDS O3M_06195 NC_018650.1 1266454 1267638 R COG0477 Permeases of the major facilitator superfamily; transport protein (ousB-like) complement(1266454..1267638) Escherichia coli O104:H4 str. 2009EL-2050 13692121 YP_006768906.1 CDS proX NC_018650.1 1267830 1268822 R COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components; glycine betaine transporter periplasmic subunit complement(1267830..1268822) Escherichia coli O104:H4 str. 2009EL-2050 13692122 YP_006768907.1 CDS O3M_06205 NC_018650.1 1268879 1269943 R COG4176 ABC-type proline/glycine betaine transport system, permease component; glycine betaine transporter membrane protein complement(1268879..1269943) Escherichia coli O104:H4 str. 2009EL-2050 13692123 YP_006768908.1 CDS O3M_06210 NC_018650.1 1269936 1271138 R COG4175 ABC-type proline/glycine betaine transport system, ATPase component; glycine betaine transporter ATP-binding subunit complement(1269936..1271138) Escherichia coli O104:H4 str. 2009EL-2050 13692124 YP_006768909.1 CDS nrdF NC_018650.1 1271493 1272452 R COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta complement(1271493..1272452) Escherichia coli O104:H4 str. 2009EL-2050 13692125 YP_006768910.1 CDS O3M_06220 NC_018650.1 1272462 1274606 R COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha complement(1272462..1274606) Escherichia coli O104:H4 str. 2009EL-2050 13692126 YP_006768911.1 CDS nrdI NC_018650.1 1274579 1274989 R COG1780 Protein involved in ribonucleotide reduction; ribonucleotide reductase stimulatory protein complement(1274579..1274989) Escherichia coli O104:H4 str. 2009EL-2050 13692127 YP_006768912.1 CDS O3M_06230 NC_018650.1 1274986 1275231 R COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein complement(1274986..1275231) Escherichia coli O104:H4 str. 2009EL-2050 13692128 YP_006768913.1 CDS O3M_06235 NC_018650.1 1275479 1275808 R COG4575 Uncharacterized conserved protein; hypothetical protein complement(1275479..1275808) Escherichia coli O104:H4 str. 2009EL-2050 13692129 YP_006768914.1 CDS O3M_06240 NC_018650.1 1275960 1276304 D hypothetical protein 1275960..1276304 Escherichia coli O104:H4 str. 2009EL-2050 13692130 YP_006768915.1 CDS O3M_06245 NC_018650.1 1276341 1276790 R hypothetical protein complement(1276341..1276790) Escherichia coli O104:H4 str. 2009EL-2050 13692131 YP_006768916.1 CDS O3M_06250 NC_018650.1 1277458 1277862 D COG2916 DNA-binding protein H-NS; DNA binding protein 1277458..1277862 Escherichia coli O104:H4 str. 2009EL-2050 13692132 YP_006768917.1 CDS O3M_06255 NC_018650.1 1277909 1278433 R COG0607 Rhodanese-related sulfurtransferase; inner membrane protein complement(1277909..1278433) Escherichia coli O104:H4 str. 2009EL-2050 13692133 YP_006768918.1 CDS O3M_06260 NC_018650.1 1278443 1278742 R COG0640 Predicted transcriptional regulators; DNA-binding transcriptional regulator complement(1278443..1278742) Escherichia coli O104:H4 str. 2009EL-2050 13692134 YP_006768919.1 CDS O3M_06265 NC_018650.1 1278925 1279083 D COG0401 Uncharacterized homolog of Blt101; hypothetical protein 1278925..1279083 Escherichia coli O104:H4 str. 2009EL-2050 13692135 YP_006768920.1 CDS O3M_06270 NC_018650.1 1279167 1279616 D COG1652 Uncharacterized protein containing LysM domain; LysM domain/BON superfamily protein 1279167..1279616 Escherichia coli O104:H4 str. 2009EL-2050 13692136 YP_006768921.1 CDS O3M_06275 NC_018650.1 1279617 1280279 R COG1802 Transcriptional regulators; DNA-binding transcriptional regulator CsiR complement(1279617..1280279) Escherichia coli O104:H4 str. 2009EL-2050 13692137 YP_006768922.1 CDS O3M_06280 NC_018650.1 1280300 1281700 R COG1113 Gamma-aminobutyrate permease and related permeases; gamma-aminobutyrate transporter complement(1280300..1281700) Escherichia coli O104:H4 str. 2009EL-2050 13692138 YP_006768923.1 CDS O3M_06285 NC_018650.1 1282011 1283291 R COG0160 4-aminobutyrate aminotransferase and related aminotransferases; 4-aminobutyrate aminotransferase complement(1282011..1283291) Escherichia coli O104:H4 str. 2009EL-2050 13692139 YP_006768924.1 CDS gabD NC_018650.1 1283305 1284753 R COG1012 NAD-dependent aldehyde dehydrogenases; succinate-semialdehyde dehydrogenase I complement(1283305..1284753) Escherichia coli O104:H4 str. 2009EL-2050 13692140 YP_006768925.1 CDS O3M_06295 NC_018650.1 1284776 1286044 R COG0579 Predicted dehydrogenase; hydroxyglutarate oxidase complement(1284776..1286044) Escherichia coli O104:H4 str. 2009EL-2050 13692141 YP_006768926.1 CDS O3M_06300 NC_018650.1 1286064 1287041 R carbon starvation induced protein complement(1286064..1287041) Escherichia coli O104:H4 str. 2009EL-2050 13692142 YP_006768927.1 CDS O3M_06305 NC_018650.1 1287377 1287649 R hypothetical protein complement(1287377..1287649) Escherichia coli O104:H4 str. 2009EL-2050 13692143 YP_006768928.1 CDS O3M_06310 NC_018650.1 1287984 1289279 R COG0366 Glycosidases; alpha-amylase complement(1287984..1289279) Escherichia coli O104:H4 str. 2009EL-2050 13692144 YP_006768929.1 CDS O3M_06330 NC_018650.1 1293740 1294486 R COG2801 Transposase and inactivated derivatives; IS602 transposase OrfB complement(1293740..1294486) Escherichia coli O104:H4 str. 2009EL-2050 13692146 YP_006768930.1 CDS O3M_06335 NC_018650.1 1294606 1294953 R COG2963 Transposase and inactivated derivatives; IS602 transposase OrfA complement(1294606..1294953) Escherichia coli O104:H4 str. 2009EL-2050 13692147 YP_006768931.1 CDS O3M_06345 NC_018650.1 1295439 1295678 R COG3311 Predicted transcriptional regulator; phage transcriptional regulator AlpA complement(1295439..1295678) Escherichia coli O104:H4 str. 2009EL-2050 13692148 YP_006768932.1 CDS O3M_06350 NC_018650.1 1295792 1296673 D hypothetical protein 1295792..1296673 Escherichia coli O104:H4 str. 2009EL-2050 13692149 YP_006768933.1 CDS O3M_06355 NC_018650.1 1296941 1297120 R hypothetical protein complement(1296941..1297120) Escherichia coli O104:H4 str. 2009EL-2050 13692150 YP_006768934.1 CDS O3M_06360 NC_018650.1 1297107 1297853 R hypothetical protein complement(1297107..1297853) Escherichia coli O104:H4 str. 2009EL-2050 13692232 YP_006768935.1 CDS O3M_06365 NC_018650.1 1297899 1301750 R COG2925 Exonuclease I; hypothetical protein complement(1297899..1301750) Escherichia coli O104:H4 str. 2009EL-2050 13692233 YP_006768936.1 CDS O3M_06370 NC_018650.1 1302218 1305964 D hypothetical protein 1302218..1305964 Escherichia coli O104:H4 str. 2009EL-2050 13692234 YP_006768937.1 CDS O3M_06375 NC_018650.1 1306103 1307344 R COG0582 Integrase; integrase complement(1306103..1307344) Escherichia coli O104:H4 str. 2009EL-2050 13692235 YP_006768938.1 CDS smpB NC_018650.1 1308127 1308609 R COG0691 tmRNA-binding protein; ssrA-binding protein complement(1308127..1308609) Escherichia coli O104:H4 str. 2009EL-2050 13692236 YP_006768939.1 CDS O3M_06385 NC_018650.1 1308780 1309217 D COG2867 Oligoketide cyclase/lipid transport protein; hypothetical protein 1308780..1309217 Escherichia coli O104:H4 str. 2009EL-2050 13692237 YP_006768940.1 CDS O3M_06390 NC_018650.1 1309207 1309497 D COG2914 Uncharacterized protein conserved in bacteria; hypothetical protein 1309207..1309497 Escherichia coli O104:H4 str. 2009EL-2050 13692238 YP_006768941.1 CDS O3M_06395 NC_018650.1 1309559 1309900 R COG2913 Small protein A (tmRNA-binding); outer membrane biogenesis protein BamE complement(1309559..1309900) Escherichia coli O104:H4 str. 2009EL-2050 13692239 YP_006768942.1 CDS O3M_06400 NC_018650.1 1310049 1311710 R COG0497 ATPase involved in DNA repair; recombination and repair protein complement(1310049..1311710) Escherichia coli O104:H4 str. 2009EL-2050 13692240 YP_006768943.1 CDS O3M_06405 NC_018650.1 1311796 1312674 R COG0061 Predicted sugar kinase; inorganic polyphosphate/ATP-NAD kinase complement(1311796..1312674) Escherichia coli O104:H4 str. 2009EL-2050 13692241 YP_006768944.1 CDS O3M_06410 NC_018650.1 1312797 1313390 D COG0576 Molecular chaperone GrpE (heat shock protein); heat shock protein HSP70 cofactor 1312797..1313390 Escherichia coli O104:H4 str. 2009EL-2050 13692242 YP_006768945.1 CDS O3M_06415 NC_018650.1 1313445 1314641 R COG4536 Putative Mg2+ and Co2+ transporter CorB; hypothetical protein complement(1313445..1314641) Escherichia coli O104:H4 str. 2009EL-2050 13692243 YP_006768946.1 CDS O3M_06420 NC_018650.1 1314752 1315543 R COG4137 ABC-type uncharacterized transport system, permease component; hypothetical protein complement(1314752..1315543) Escherichia coli O104:H4 str. 2009EL-2050 13692244 YP_006768947.1 CDS O3M_06425 NC_018650.1 1315710 1317071 D COG0541 Signal recognition particle GTPase; signal recognition particle protein 1315710..1317071 Escherichia coli O104:H4 str. 2009EL-2050 13692245 YP_006768948.1 CDS rpsP NC_018650.1 1317208 1317456 D COG0228 Ribosomal protein S16; 30S ribosomal protein S16 1317208..1317456 Escherichia coli O104:H4 str. 2009EL-2050 13692246 YP_006768949.1 CDS rimM NC_018650.1 1317475 1318023 D COG0806 RimM protein, required for 16S rRNA processing; 16S rRNA-processing protein RimM 1317475..1318023 Escherichia coli O104:H4 str. 2009EL-2050 13692247 YP_006768950.1 CDS trmD NC_018650.1 1318054 1318821 D COG0336 tRNA-(guanine-N1)-methyltransferase; tRNA (guanine-N(1)-)-methyltransferase 1318054..1318821 Escherichia coli O104:H4 str. 2009EL-2050 13692248 YP_006768951.1 CDS rplS NC_018650.1 1318863 1319210 D COG0335 Ribosomal protein L19; 50S ribosomal protein L19 1318863..1319210 Escherichia coli O104:H4 str. 2009EL-2050 13692249 YP_006768952.1 CDS O3M_06450 NC_018650.1 1319287 1319769 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; outer membrane lipoprotein complement(1319287..1319769) Escherichia coli O104:H4 str. 2009EL-2050 13692250 YP_006768953.1 CDS O3M_06455 NC_018650.1 1319785 1321011 R COG2199 FOG: GGDEF domain; inner membrane diguanylate cyclase complement(1319785..1321011) Escherichia coli O104:H4 str. 2009EL-2050 13692251 YP_006768954.1 CDS O3M_06460 NC_018650.1 1321001 1321519 R hypothetical protein complement(1321001..1321519) Escherichia coli O104:H4 str. 2009EL-2050 13692252 YP_006768955.1 CDS O3M_06465 NC_018650.1 1321669 1322034 R COG0178 Excinuclease ATPase subunit; lipoprotein complement(1321669..1322034) Escherichia coli O104:H4 str. 2009EL-2050 13692253 YP_006768956.1 CDS O3M_06470 NC_018650.1 1322244 1323314 D COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase 1322244..1323314 Escherichia coli O104:H4 str. 2009EL-2050 13692254 YP_006768957.1 CDS tyrA NC_018650.1 1323325 1324446 D COG1605 Chorismate mutase; bifunctional chorismate mutase/prephenate dehydrogenase 1323325..1324446 Escherichia coli O104:H4 str. 2009EL-2050 13692255 YP_006768958.1 CDS pheA NC_018650.1 1324489 1325649 R COG1605 Chorismate mutase; bifunctional chorismate mutase/prephenate dehydratase complement(1324489..1325649) Escherichia coli O104:H4 str. 2009EL-2050 13692256 YP_006768959.1 CDS O3M_06485 NC_018650.1 1325899 1326240 R COG1544 Ribosome-associated protein Y (PSrp-1); translation inhibitor protein RaiA complement(1325899..1326240) Escherichia coli O104:H4 str. 2009EL-2050 13692257 YP_006768960.1 CDS O3M_06490 NC_018650.1 1326511 1327248 R COG4105 DNA uptake lipoprotein; outer membrane biogenesis protein BamD complement(1326511..1327248) Escherichia coli O104:H4 str. 2009EL-2050 13692258 YP_006768961.1 CDS rluD NC_018650.1 1327383 1328363 D COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA pseudouridine synthase D 1327383..1328363 Escherichia coli O104:H4 str. 2009EL-2050 13692259 YP_006768962.1 CDS O3M_06500 NC_018650.1 1328360 1329091 D COG1496 Uncharacterized conserved protein; hypothetical protein 1328360..1329091 Escherichia coli O104:H4 str. 2009EL-2050 13692260 YP_006768963.1 CDS O3M_06505 NC_018650.1 1329221 1331794 D COG0542 ATPases with chaperone activity, ATP-binding subunit; protein disaggregation chaperone 1329221..1331794 Escherichia coli O104:H4 str. 2009EL-2050 13692261 YP_006768964.1 CDS O3M_06510 NC_018650.1 1337662 1338960 D COG0477 Permeases of the major facilitator superfamily; alpha-ketoglutarate transporter 1337662..1338960 Escherichia coli O104:H4 str. 2009EL-2050 13692266 YP_006768965.1 CDS O3M_06515 NC_018650.1 1338957 1339280 R COG5544 Predicted periplasmic lipoprotein; lipoprotein complement(1338957..1339280) Escherichia coli O104:H4 str. 2009EL-2050 13692267 YP_006768966.1 CDS pssA NC_018650.1 1339326 1340681 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phosphatidylserine synthase complement(1339326..1340681) Escherichia coli O104:H4 str. 2009EL-2050 13692268 YP_006768967.1 CDS O3M_06525 NC_018650.1 1340795 1343455 R ATP-binding subunit; COG1042 Acyl-CoA synthetase (NDP forming); acyl-CoA synthetase NAD(P)-binding subunit complement(1340795..1343455) Escherichia coli O104:H4 str. 2009EL-2050 13692269 YP_006768968.1 CDS O3M_06530 NC_018650.1 1343487 1344185 R COG3148 Uncharacterized conserved protein; DTW domain-containing protein yfiP complement(1343487..1344185) Escherichia coli O104:H4 str. 2009EL-2050 13692270 YP_006768969.1 CDS O3M_06535 NC_018650.1 1344254 1344673 R COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 2 complement(1344254..1344673) Escherichia coli O104:H4 str. 2009EL-2050 13692271 YP_006768970.1 CDS O3M_06540 NC_018650.1 1344880 1345917 D COG0566 rRNA methylases; methyltransferase 1344880..1345917 Escherichia coli O104:H4 str. 2009EL-2050 13692272 YP_006768971.1 CDS O3M_06545 NC_018650.1 1345965 1346654 R COG0692 Uracil DNA glycosylase; uracil-DNA glycosylase complement(1345965..1346654) Escherichia coli O104:H4 str. 2009EL-2050 13692273 YP_006768972.1 CDS O3M_06550 NC_018650.1 1346959 1347342 D COG3445 Acid-induced glycyl radical enzyme; autonomous glycyl radical cofactor GrcA 1346959..1347342 Escherichia coli O104:H4 str. 2009EL-2050 13692274 YP_006768973.1 CDS O3M_06555 NC_018650.1 1347397 1347984 R COG1280 Putative threonine efflux protein; cysteine/O-acetylserine exporter complement(1347397..1347984) Escherichia coli O104:H4 str. 2009EL-2050 13692275 YP_006768974.1 CDS O3M_06560 NC_018650.1 1348087 1348968 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 1348087..1348968 Escherichia coli O104:H4 str. 2009EL-2050 13692276 YP_006768975.1 CDS O3M_06565 NC_018650.1 1349019 1349171 R hypothetical protein complement(1349019..1349171) Escherichia coli O104:H4 str. 2009EL-2050 13692277 YP_006768976.1 CDS O3M_06570 NC_018650.1 1349177 1350511 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase SrmB complement(1349177..1350511) Escherichia coli O104:H4 str. 2009EL-2050 13692278 YP_006768977.1 CDS O3M_06575 NC_018650.1 1350643 1351380 D COG4123 Predicted O-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase 1350643..1351380 Escherichia coli O104:H4 str. 2009EL-2050 13692279 YP_006768978.1 CDS O3M_06580 NC_018650.1 1351365 1352987 R COG0029 Aspartate oxidase; L-aspartate oxidase complement(1351365..1352987) Escherichia coli O104:H4 str. 2009EL-2050 13692280 YP_006768979.1 CDS O3M_06585 NC_018650.1 1353243 1353398 D hypothetical protein 1353243..1353398 Escherichia coli O104:H4 str. 2009EL-2050 13692281 YP_006768980.1 CDS O3M_06590 NC_018650.1 1353395 1353970 D COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor RpoE 1353395..1353970 Escherichia coli O104:H4 str. 2009EL-2050 13692282 YP_006768981.1 CDS O3M_06595 NC_018650.1 1354003 1354653 D COG3073 Negative regulator of sigma E activity; anti-RNA polymerase sigma factor SigE 1354003..1354653 Escherichia coli O104:H4 str. 2009EL-2050 13692283 YP_006768982.1 CDS rseB NC_018650.1 1354653 1355609 D COG3026 Negative regulator of sigma E activity; anti-sigma E factor 1354653..1355609 Escherichia coli O104:H4 str. 2009EL-2050 13692284 YP_006768983.1 CDS O3M_06605 NC_018650.1 1355606 1356085 D COG3086 Positive regulator of sigma E activity; SoxR reducing system protein RseC 1355606..1356085 Escherichia coli O104:H4 str. 2009EL-2050 13692285 YP_006768984.1 CDS O3M_06610 NC_018650.1 1356283 1358082 D COG0481 Membrane GTPase LepA; GTP-binding protein LepA 1356283..1358082 Escherichia coli O104:H4 str. 2009EL-2050 13692286 YP_006768985.1 CDS O3M_06615 NC_018650.1 1358098 1359072 D COG0681 Signal peptidase I; signal peptidase I 1358098..1359072 Escherichia coli O104:H4 str. 2009EL-2050 13692287 YP_006768986.1 CDS rnc NC_018650.1 1359345 1360025 D COG0571 dsRNA-specific ribonuclease; ribonuclease III 1359345..1360025 Escherichia coli O104:H4 str. 2009EL-2050 13692288 YP_006768987.1 CDS era NC_018650.1 1360022 1360927 D COG1159 GTPase; GTPase Era 1360022..1360927 Escherichia coli O104:H4 str. 2009EL-2050 13692289 YP_006768988.1 CDS recO NC_018650.1 1360939 1361667 D COG1381 Recombinational DNA repair protein (RecF pathway); DNA repair protein RecO 1360939..1361667 Escherichia coli O104:H4 str. 2009EL-2050 13692290 YP_006768989.1 CDS O3M_06635 NC_018650.1 1361679 1362410 D COG0854 Pyridoxal phosphate biosynthesis protein; pyridoxine 5'-phosphate synthase 1361679..1362410 Escherichia coli O104:H4 str. 2009EL-2050 13692291 YP_006768990.1 CDS acpS NC_018650.1 1362410 1362790 D COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); 4'-phosphopantetheinyl transferase 1362410..1362790 Escherichia coli O104:H4 str. 2009EL-2050 13692292 YP_006768991.1 CDS O3M_06645 NC_018650.1 1363210 1363290 D toxic membrane protein 1363210..1363290 Escherichia coli O104:H4 str. 2009EL-2050 13692293 YP_006768992.1 CDS O3M_06650 NC_018650.1 1363484 1363744 R COG1145 Ferredoxin; 4Fe-4S binding protein complement(1363484..1363744) Escherichia coli O104:H4 str. 2009EL-2050 13692294 YP_006768993.1 CDS O3M_06655 NC_018650.1 1363800 1364648 R COG1737 Transcriptional regulators; DNA-binding transcriptional regulator complement(1363800..1364648) Escherichia coli O104:H4 str. 2009EL-2050 13692295 YP_006768994.1 CDS O3M_06660 NC_018650.1 1364857 1365492 D COG0560 Phosphoserine phosphatase; hypothetical protein 1364857..1365492 Escherichia coli O104:H4 str. 2009EL-2050 13692296 YP_006768995.1 CDS O3M_06665 NC_018650.1 1365517 1366053 D COG0590 Cytosine/adenosine deaminases; tRNA-specific adenosine deaminase 1365517..1366053 Escherichia coli O104:H4 str. 2009EL-2050 13692297 YP_006768996.1 CDS O3M_06670 NC_018650.1 1366050 1367606 R COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein; membrane-bound lytic transglycosylase F complement(1366050..1367606) Escherichia coli O104:H4 str. 2009EL-2050 13692298 YP_006768997.1 CDS O3M_06675 NC_018650.1 1367867 1371751 D COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine synthase 1367867..1371751 Escherichia coli O104:H4 str. 2009EL-2050 13692299 YP_006768998.1 CDS O3M_06680 NC_018650.1 1372327 1373754 D COG0642 Signal transduction histidine kinase; 2-component sensor protein 1372327..1373754 Escherichia coli O104:H4 str. 2009EL-2050 13692300 YP_006768999.1 CDS O3M_06685 NC_018650.1 1373919 1374632 D hypothetical protein 1373919..1374632 Escherichia coli O104:H4 str. 2009EL-2050 13692301 YP_006769000.1 CDS O3M_06690 NC_018650.1 1374622 1375956 D COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; response regulator GlrR 1374622..1375956 Escherichia coli O104:H4 str. 2009EL-2050 13692302 YP_006769001.1 CDS O3M_06695 NC_018650.1 1376017 1376355 D COG0347 Nitrogen regulatory protein PII; nitrogen regulatory protein P-II 1 1376017..1376355 Escherichia coli O104:H4 str. 2009EL-2050 13692303 YP_006769002.1 CDS O3M_06700 NC_018650.1 1376400 1377590 R COG1017 Hemoglobin-like flavoprotein; bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2 complement(1376400..1377590) Escherichia coli O104:H4 str. 2009EL-2050 13692304 YP_006769003.1 CDS glyA NC_018650.1 1377918 1379171 D COG0112 Glycine/serine hydroxymethyltransferase; serine hydroxymethyltransferase 1377918..1379171 Escherichia coli O104:H4 str. 2009EL-2050 13692305 YP_006769004.1 CDS O3M_06710 NC_018650.1 1379235 1380428 R COG1940 Transcriptional regulator/sugar kinase; DNA-binding transcriptional regulator complement(1379235..1380428) Escherichia coli O104:H4 str. 2009EL-2050 13692306 YP_006769005.1 CDS O3M_06715 NC_018650.1 1380546 1383827 D COG0457 FOG: TPR repeat; hypothetical protein 1380546..1383827 Escherichia coli O104:H4 str. 2009EL-2050 13692307 YP_006769006.1 CDS O3M_06720 NC_018650.1 1383924 1384907 D COG1879 ABC-type sugar transport system, periplasmic component; sugar ABC transporter substrate-binding protein 1383924..1384907 Escherichia coli O104:H4 str. 2009EL-2050 13692308 YP_006769007.1 CDS O3M_06725 NC_018650.1 1384930 1386441 D COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein 1384930..1386441 Escherichia coli O104:H4 str. 2009EL-2050 13692309 YP_006769008.1 CDS O3M_06730 NC_018650.1 1386466 1387464 D COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar transporter subunit 1386466..1387464 Escherichia coli O104:H4 str. 2009EL-2050 13692310 YP_006769009.1 CDS O3M_06735 NC_018650.1 1387530 1388591 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein 1387530..1388591 Escherichia coli O104:H4 str. 2009EL-2050 13692311 YP_006769010.1 CDS O3M_06740 NC_018650.1 1388603 1389475 D COG2017 Galactose mutarotase and related enzymes; hypothetical protein 1388603..1389475 Escherichia coli O104:H4 str. 2009EL-2050 13692312 YP_006769011.1 CDS O3M_06745 NC_018650.1 1389523 1389945 R COG2259 Predicted membrane protein; inner membrane protein complement(1389523..1389945) Escherichia coli O104:H4 str. 2009EL-2050 13692394 YP_006769012.1 CDS O3M_06750 NC_018650.1 1390042 1391244 R COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; phenylpropionate dioxygenase ferredoxin reductase subunit complement(1390042..1391244) Escherichia coli O104:H4 str. 2009EL-2050 13692395 YP_006769013.1 CDS O3M_06755 NC_018650.1 1391254 1392066 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase complement(1391254..1392066) Escherichia coli O104:H4 str. 2009EL-2050 13692396 YP_006769014.1 CDS O3M_06760 NC_018650.1 1392063 1392383 R COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; 3-phenylpropionate dioxygenase ferredoxin subunit complement(1392063..1392383) Escherichia coli O104:H4 str. 2009EL-2050 13692397 YP_006769015.1 CDS O3M_06765 NC_018650.1 1392383 1392901 R COG5517 Small subunit of phenylpropionate dioxygenase; 3-phenylpropionate dioxygenase subunit beta complement(1392383..1392901) Escherichia coli O104:H4 str. 2009EL-2050 13692398 YP_006769016.1 CDS O3M_06770 NC_018650.1 1392898 1394259 R COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha complement(1392898..1394259) Escherichia coli O104:H4 str. 2009EL-2050 13692399 YP_006769017.1 CDS O3M_06775 NC_018650.1 1394395 1395285 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator HcaR 1394395..1395285 Escherichia coli O104:H4 str. 2009EL-2050 13692400 YP_006769018.1 CDS O3M_06780 NC_018650.1 1395445 1396584 D COG0477 Permeases of the major facilitator superfamily; 3-phenylpropionic acid transporter 1395445..1396584 Escherichia coli O104:H4 str. 2009EL-2050 13692401 YP_006769019.1 CDS O3M_06785 NC_018650.1 1396576 1397856 R COG3711 Transcriptional antiterminator; stationary phase inducible protein CsiE complement(1396576..1397856) Escherichia coli O104:H4 str. 2009EL-2050 13692402 YP_006769020.1 CDS O3M_06790 NC_018650.1 1398047 1398901 R COG1073 Hydrolases of the alpha/beta superfamily; peptidase complement(1398047..1398901) Escherichia coli O104:H4 str. 2009EL-2050 13692403 YP_006769021.1 CDS O3M_06795 NC_018650.1 1399046 1399849 R COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; inositol monophosphatase complement(1399046..1399849) Escherichia coli O104:H4 str. 2009EL-2050 13692404 YP_006769022.1 CDS O3M_06800 NC_018650.1 1399968 1400708 D COG0565 rRNA methylase; tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ 1399968..1400708 Escherichia coli O104:H4 str. 2009EL-2050 13692405 YP_006769023.1 CDS O3M_06805 NC_018650.1 1400978 1401466 D COG1959 Predicted transcriptional regulator; DNA-binding transcriptional regulator IscR 1400978..1401466 Escherichia coli O104:H4 str. 2009EL-2050 13692406 YP_006769024.1 CDS O3M_06810 NC_018650.1 1401578 1402792 D COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine desulfurase 1401578..1402792 Escherichia coli O104:H4 str. 2009EL-2050 13692407 YP_006769025.1 CDS O3M_06815 NC_018650.1 1402820 1403206 D COG0822 NifU homolog involved in Fe-S cluster formation; scaffold protein 1402820..1403206 Escherichia coli O104:H4 str. 2009EL-2050 13692408 YP_006769026.1 CDS iscA NC_018650.1 1403223 1403546 D COG0316 Uncharacterized conserved protein; iron-sulfur cluster assembly protein 1403223..1403546 Escherichia coli O104:H4 str. 2009EL-2050 13692409 YP_006769027.1 CDS hscB NC_018650.1 1403642 1404157 D COG1076 DnaJ-domain-containing proteins 1; co-chaperone HscB 1403642..1404157 Escherichia coli O104:H4 str. 2009EL-2050 13692410 YP_006769028.1 CDS hscA NC_018650.1 1404174 1406024 D COG0443 Molecular chaperone; chaperone protein HscA 1404174..1406024 Escherichia coli O104:H4 str. 2009EL-2050 13692411 YP_006769029.1 CDS O3M_06835 NC_018650.1 1406026 1406361 D COG0633 Ferredoxin; 2Fe-2S ferredoxin 1406026..1406361 Escherichia coli O104:H4 str. 2009EL-2050 13692412 YP_006769030.1 CDS O3M_06840 NC_018650.1 1406373 1406573 D COG2975 Uncharacterized protein conserved in bacteria; hypothetical protein 1406373..1406573 Escherichia coli O104:H4 str. 2009EL-2050 13692413 YP_006769031.1 CDS O3M_06845 NC_018650.1 1406751 1408034 D COG0260 Leucyl aminopeptidase; aminopeptidase B 1406751..1408034 Escherichia coli O104:H4 str. 2009EL-2050 13692414 YP_006769032.1 CDS O3M_06850 NC_018650.1 1408176 1408952 D enhanced serine sensitivity protein SseB 1408176..1408952 Escherichia coli O104:H4 str. 2009EL-2050 13692415 YP_006769033.1 CDS sseA NC_018650.1 1409445 1410290 R COG2897 Rhodanese-related sulfurtransferase; 3-mercaptopyruvate sulfurtransferase complement(1409445..1410290) Escherichia coli O104:H4 str. 2009EL-2050 13692416 YP_006769034.1 CDS O3M_06860 NC_018650.1 1410497 1415458 D COG2373 Large extracellular alpha-helical protein; hypothetical protein 1410497..1415458 Escherichia coli O104:H4 str. 2009EL-2050 13692417 YP_006769035.1 CDS O3M_06865 NC_018650.1 1415459 1417771 D COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; penicillin-binding protein 1C 1415459..1417771 Escherichia coli O104:H4 str. 2009EL-2050 13692418 YP_006769036.1 CDS ndk NC_018650.1 1417920 1418351 D COG0105 Nucleoside diphosphate kinase; mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase 1417920..1418351 Escherichia coli O104:H4 str. 2009EL-2050 13692419 YP_006769037.1 CDS O3M_06875 NC_018650.1 1418501 1419655 D COG0820 Predicted Fe-S-cluster redox enzyme; ribosomal RNA large subunit methyltransferase N 1418501..1419655 Escherichia coli O104:H4 str. 2009EL-2050 13692420 YP_006769038.1 CDS O3M_06880 NC_018650.1 1419940 1420953 D COG1426 Uncharacterized protein conserved in bacteria; cytoskeletal protein RodZ 1419940..1420953 Escherichia coli O104:H4 str. 2009EL-2050 13692421 YP_006769039.1 CDS ispG NC_018650.1 1420980 1422098 D COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1420980..1422098 Escherichia coli O104:H4 str. 2009EL-2050 13692422 YP_006769040.1 CDS hisS NC_018650.1 1422209 1423483 D COG0124 Histidyl-tRNA synthetase; histidyl-tRNA synthetase 1422209..1423483 Escherichia coli O104:H4 str. 2009EL-2050 13692423 YP_006769041.1 CDS O3M_06895 NC_018650.1 1423501 1424121 D COG2976 Uncharacterized protein conserved in bacteria; hypothetical protein 1423501..1424121 Escherichia coli O104:H4 str. 2009EL-2050 13692424 YP_006769042.1 CDS O3M_06900 NC_018650.1 1424132 1425310 D COG1520 FOG: WD40-like repeat; outer membrane biogenesis protein BamB 1424132..1425310 Escherichia coli O104:H4 str. 2009EL-2050 13692425 YP_006769043.1 CDS O3M_06905 NC_018650.1 1425428 1426900 D COG1160 Predicted GTPases; GTP-binding protein Der 1425428..1426900 Escherichia coli O104:H4 str. 2009EL-2050 13692426 YP_006769044.1 CDS O3M_06910 NC_018650.1 1426969 1427184 D COG1933 Archaeal DNA polymerase II, large subunit; hypothetical protein 1426969..1427184 Escherichia coli O104:H4 str. 2009EL-2050 13692427 YP_006769045.1 CDS xseA NC_018650.1 1427181 1428551 R COG1570 Exonuclease VII, large subunit; exodeoxyribonuclease VII large subunit complement(1427181..1428551) Escherichia coli O104:H4 str. 2009EL-2050 13692428 YP_006769046.1 CDS O3M_06920 NC_018650.1 1428713 1430179 D COG0516 IMP dehydrogenase/GMP reductase; inosine 5'-monophosphate dehydrogenase 1428713..1430179 Escherichia coli O104:H4 str. 2009EL-2050 13692429 YP_006769047.1 CDS guaA NC_018650.1 1430248 1431825 D COG0518 GMP synthase - Glutamine amidotransferase domain; GMP synthase 1430248..1431825 Escherichia coli O104:H4 str. 2009EL-2050 13692430 YP_006769048.1 CDS O3M_06930 NC_018650.1 1431918 1432457 R hypothetical protein complement(1431918..1432457) Escherichia coli O104:H4 str. 2009EL-2050 13692431 YP_006769049.1 CDS O3M_06935 NC_018650.1 1432473 1432991 R outer membrane lipoprotein complement(1432473..1432991) Escherichia coli O104:H4 str. 2009EL-2050 13692432 YP_006769050.1 CDS O3M_06940 NC_018650.1 1433302 1433493 R hypothetical protein complement(1433302..1433493) Escherichia coli O104:H4 str. 2009EL-2050 13692433 YP_006769051.1 CDS O3M_06945 NC_018650.1 1433511 1433663 D hypothetical protein 1433511..1433663 Escherichia coli O104:H4 str. 2009EL-2050 13692434 YP_006769052.1 CDS O3M_06950 NC_018650.1 1433845 1436088 D COG2199 FOG: GGDEF domain; inner membrane protein 1433845..1436088 Escherichia coli O104:H4 str. 2009EL-2050 13692435 YP_006769053.1 CDS O3M_06955 NC_018650.1 1436127 1437668 R COG0248 Exopolyphosphatase; exopolyphosphatase complement(1436127..1437668) Escherichia coli O104:H4 str. 2009EL-2050 13692436 YP_006769054.1 CDS O3M_06960 NC_018650.1 1437673 1439739 R COG0855 Polyphosphate kinase; polyphosphate kinase complement(1437673..1439739) Escherichia coli O104:H4 str. 2009EL-2050 13692437 YP_006769055.1 CDS purN NC_018650.1 1439910 1440548 R COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; phosphoribosylglycinamide formyltransferase complement(1439910..1440548) Escherichia coli O104:H4 str. 2009EL-2050 13692438 YP_006769056.1 CDS O3M_06970 NC_018650.1 1440548 1441585 R COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; phosphoribosylaminoimidazole synthetase complement(1440548..1441585) Escherichia coli O104:H4 str. 2009EL-2050 13692439 YP_006769057.1 CDS upp NC_018650.1 1441910 1442536 D COG0035 Uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 1441910..1442536 Escherichia coli O104:H4 str. 2009EL-2050 13692440 YP_006769058.1 CDS O3M_06980 NC_018650.1 1442622 1443911 D COG2233 Xanthine/uracil permeases; uracil transporter 1442622..1443911 Escherichia coli O104:H4 str. 2009EL-2050 13692441 YP_006769059.1 CDS O3M_06985 NC_018650.1 1443961 1444707 D COG0593 ATPase involved in DNA replication initiation; DNA replication initiation factor 1443961..1444707 Escherichia coli O104:H4 str. 2009EL-2050 13692442 YP_006769060.1 CDS O3M_06990 NC_018650.1 1444845 1445204 R COG1393 Arsenate reductase and related proteins, glutaredoxin family; oxidoreductase complement(1444845..1445204) Escherichia coli O104:H4 str. 2009EL-2050 13692443 YP_006769061.1 CDS O3M_06995 NC_018650.1 1445225 1446688 R COG4783 Putative Zn-dependent protease, contains TPR repeats; peptidase, M48 family protein complement(1445225..1446688) Escherichia coli O104:H4 str. 2009EL-2050 13692444 YP_006769062.1 CDS O3M_07000 NC_018650.1 1446901 1447962 D COG0628 Predicted permease; permease perM 1446901..1447962 Escherichia coli O104:H4 str. 2009EL-2050 13692445 YP_006769063.1 CDS O3M_07005 NC_018650.1 1448116 1448847 R COG2116 Formate/nitrite family of transporters; formate transporter complement(1448116..1448847) Escherichia coli O104:H4 str. 2009EL-2050 13692446 YP_006769064.1 CDS O3M_07010 NC_018650.1 1448869 1450881 R COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; DNA-binding transcriptional activator, formate sensing complement(1448869..1450881) Escherichia coli O104:H4 str. 2009EL-2050 13692447 YP_006769065.1 CDS O3M_07015 NC_018650.1 1450911 1451324 R formate hydrogenlyase maturation protein HycH complement(1450911..1451324) Escherichia coli O104:H4 str. 2009EL-2050 13692448 YP_006769066.1 CDS O3M_07020 NC_018650.1 1451317 1452075 R COG3260 Ni,Fe-hydrogenase III small subunit; hydrogenase 4, Fe-S subunit complement(1451317..1452075) Escherichia coli O104:H4 str. 2009EL-2050 13692449 YP_006769067.1 CDS O3M_07025 NC_018650.1 1452072 1452611 R COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); hydrogenase 4 subunit H complement(1452072..1452611) Escherichia coli O104:H4 str. 2009EL-2050 13692450 YP_006769068.1 CDS O3M_07030 NC_018650.1 1452621 1454336 R COG3262 Ni,Fe-hydrogenase III component G; hydrogenase 4 membrane subunit complement(1452621..1454336) Escherichia coli O104:H4 str. 2009EL-2050 13692451 YP_006769069.1 CDS O3M_07035 NC_018650.1 1454326 1455906 R COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hydrogenase 4 subunit F complement(1454326..1455906) Escherichia coli O104:H4 str. 2009EL-2050 13692452 YP_006769070.1 CDS hyfE NC_018650.1 1455911 1456561 R COG4237 Hydrogenase 4 membrane component (E); hydrogenase 4 membrane subunit complement(1455911..1456561) Escherichia coli O104:H4 str. 2009EL-2050 13692453 YP_006769071.1 CDS O3M_07045 NC_018650.1 1456573 1457559 R COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; hydrogenase 4 subunit D complement(1456573..1457559) Escherichia coli O104:H4 str. 2009EL-2050 13692454 YP_006769072.1 CDS O3M_07050 NC_018650.1 1457556 1458011 R COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; hydrogenase 4 membrane subunit complement(1457556..1458011) Escherichia coli O104:H4 str. 2009EL-2050 13692455 YP_006769073.1 CDS O3M_07055 NC_018650.1 1458028 1458162 R hydrogenase 4 membrane subunit complement(1458028..1458162) Escherichia coli O104:H4 str. 2009EL-2050 13692456 YP_006769074.1 CDS O3M_07060 NC_018650.1 1458217 1458975 R COG0650 Formate hydrogenlyase subunit 4; hydrogenase 4 membrane subunit complement(1458217..1458975) Escherichia coli O104:H4 str. 2009EL-2050 13692457 YP_006769075.1 CDS O3M_07065 NC_018650.1 1458986 1461004 R COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hydrogenase 4 subunit B complement(1458986..1461004) Escherichia coli O104:H4 str. 2009EL-2050 13692458 YP_006769076.1 CDS O3M_07070 NC_018650.1 1461004 1461621 R COG1142 Fe-S-cluster-containing hydrogenase components 2; hydrogenase 4, 4Fe-4S subunit complement(1461004..1461621) Escherichia coli O104:H4 str. 2009EL-2050 13692459 YP_006769077.1 CDS bcp NC_018650.1 1461874 1462344 R COG1225 Peroxiredoxin; thioredoxin-dependent thiol peroxidase complement(1461874..1462344) Escherichia coli O104:H4 str. 2009EL-2050 13692460 YP_006769078.1 CDS gcvR NC_018650.1 1462344 1462916 R COG2716 Glycine cleavage system regulatory protein; glycine cleavage system transcriptional repressor complement(1462344..1462916) Escherichia coli O104:H4 str. 2009EL-2050 13692461 YP_006769079.1 CDS O3M_07085 NC_018650.1 1463062 1463940 D COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase 1463062..1463940 Escherichia coli O104:H4 str. 2009EL-2050 13692462 YP_006769080.1 CDS O3M_07090 NC_018650.1 1463957 1464991 D COG3317 Uncharacterized lipoprotein; lipoprotein 1463957..1464991 Escherichia coli O104:H4 str. 2009EL-2050 13692463 YP_006769081.1 CDS O3M_07095 NC_018650.1 1464902 1465153 R hypothetical protein complement(1464902..1465153) Escherichia coli O104:H4 str. 2009EL-2050 13692464 YP_006769082.1 CDS O3M_07100 NC_018650.1 1465204 1465917 D COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazole succinocarboxamide synthase 1465204..1465917 Escherichia coli O104:H4 str. 2009EL-2050 13692465 YP_006769083.1 CDS O3M_07105 NC_018650.1 1466072 1466299 D COG4456 Virulence-associated protein and related proteins; transcriptional regulation protein 1466072..1466299 Escherichia coli O104:H4 str. 2009EL-2050 13692466 YP_006769084.1 CDS O3M_07110 NC_018650.1 1466299 1466697 D COG1487 Predicted nucleic acid-binding protein, contains PIN domain; plasmid maintenance protein 1466299..1466697 Escherichia coli O104:H4 str. 2009EL-2050 13692467 YP_006769085.1 CDS O3M_07115 NC_018650.1 1466844 1467707 D COG2321 Predicted metalloprotease; hypothetical protein 1466844..1467707 Escherichia coli O104:H4 str. 2009EL-2050 13692468 YP_006769086.1 CDS O3M_07120 NC_018650.1 1467722 1469737 D COG1444 Predicted P-loop ATPase fused to an acetyltransferase; hydrolase 1467722..1469737 Escherichia coli O104:H4 str. 2009EL-2050 13692469 YP_006769087.1 CDS O3M_07125 NC_018650.1 1469811 1470509 D COG0400 Predicted esterase; hydrolase 1469811..1470509 Escherichia coli O104:H4 str. 2009EL-2050 13692470 YP_006769088.1 CDS O3M_07130 NC_018650.1 1470619 1470819 R hypothetical protein complement(1470619..1470819) Escherichia coli O104:H4 str. 2009EL-2050 13692471 YP_006769089.1 CDS O3M_07135 NC_018650.1 1470847 1471974 R COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; succinyl-diaminopimelate desuccinylase complement(1470847..1471974) Escherichia coli O104:H4 str. 2009EL-2050 13692472 YP_006769090.1 CDS O3M_07140 NC_018650.1 1471978 1472334 R COG1393 Arsenate reductase and related proteins, glutaredoxin family; reductase complement(1471978..1472334) Escherichia coli O104:H4 str. 2009EL-2050 13692473 YP_006769091.1 CDS O3M_07145 NC_018650.1 1472873 1475986 R COG0841 Cation/multidrug efflux pump; aminoglycoside/multidrug efflux system complement(1472873..1475986) Escherichia coli O104:H4 str. 2009EL-2050 13692474 YP_006769092.1 CDS O3M_07150 NC_018650.1 1476150 1477850 R COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific; nitrate/nitrite sensor protein NarQ complement(1476150..1477850) Escherichia coli O104:H4 str. 2009EL-2050 13692556 YP_006769093.1 CDS O3M_07155 NC_018650.1 1478056 1480035 D COG1142 Fe-S-cluster-containing hydrogenase components 2; oxidoreductase Fe-S binding subunit 1478056..1480035 Escherichia coli O104:H4 str. 2009EL-2050 13692557 YP_006769094.1 CDS O3M_07160 NC_018650.1 1480103 1480678 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; GDP-mannose pyrophosphatase NudK 1480103..1480678 Escherichia coli O104:H4 str. 2009EL-2050 13692558 YP_006769095.1 CDS O3M_07165 NC_018650.1 1480804 1481847 D COG1088 dTDP-D-glucose 4,6-dehydratase; hypothetical protein 1480804..1481847 Escherichia coli O104:H4 str. 2009EL-2050 13692559 YP_006769096.1 CDS O3M_07170 NC_018650.1 1481943 1483946 R COG0021 Transketolase; transketolase complement(1481943..1483946) Escherichia coli O104:H4 str. 2009EL-2050 13692560 YP_006769097.1 CDS O3M_07175 NC_018650.1 1483966 1484916 R COG0176 Transaldolase; transaldolase A complement(1483966..1484916) Escherichia coli O104:H4 str. 2009EL-2050 13692561 YP_006769098.1 CDS O3M_07180 NC_018650.1 1485205 1487484 D COG0281 Malic enzyme; bifunctional malic enzyme oxidoreductase/phosphotransacetylase 1485205..1487484 Escherichia coli O104:H4 str. 2009EL-2050 13692562 YP_006769099.1 CDS O3M_07185 NC_018650.1 1487777 1488112 D COG4810 Ethanolamine utilization protein; carboxysome structural protein EutS 1487777..1488112 Escherichia coli O104:H4 str. 2009EL-2050 13692563 YP_006769100.1 CDS O3M_07190 NC_018650.1 1488125 1488604 D COG4917 Ethanolamine utilization protein; ethanolamine utilization protein EutP 1488125..1488604 Escherichia coli O104:H4 str. 2009EL-2050 13692564 YP_006769101.1 CDS O3M_07195 NC_018650.1 1488579 1489280 D COG4766 Ethanolamine utilization protein; ethanolamine utilization protein EutQ 1488579..1489280 Escherichia coli O104:H4 str. 2009EL-2050 13692565 YP_006769102.1 CDS O3M_07200 NC_018650.1 1489277 1490080 D COG4812 Ethanolamine utilization cobalamin adenosyltransferase; ethanolamine utilization cobalamin adenosyltransferase 1489277..1490080 Escherichia coli O104:H4 str. 2009EL-2050 13692566 YP_006769103.1 CDS eutD NC_018650.1 1490077 1491093 D COG0280 Phosphotransacetylase; phosphotransacetylase 1490077..1491093 Escherichia coli O104:H4 str. 2009EL-2050 13692567 YP_006769104.1 CDS O3M_07210 NC_018650.1 1491132 1491425 D COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; carboxysome structural protein EutM 1491132..1491425 Escherichia coli O104:H4 str. 2009EL-2050 13692568 YP_006769105.1 CDS O3M_07215 NC_018650.1 1491532 1491819 D COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein; ethanolamine catabolic microcompartment shell protein EutN 1491532..1491819 Escherichia coli O104:H4 str. 2009EL-2050 13692569 YP_006769106.1 CDS O3M_07220 NC_018650.1 1491831 1493234 D COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase EutE 1491831..1493234 Escherichia coli O104:H4 str. 2009EL-2050 13692570 YP_006769107.1 CDS O3M_07225 NC_018650.1 1493245 1494081 D COG4820 Ethanolamine utilization protein, possible chaperonin; ethanolamine utilization protein EutJ 1493245..1494081 Escherichia coli O104:H4 str. 2009EL-2050 13692571 YP_006769108.1 CDS O3M_07230 NC_018650.1 1494071 1495258 D COG1454 Alcohol dehydrogenase, class IV; ethanol dehydrogenase EutG 1494071..1495258 Escherichia coli O104:H4 str. 2009EL-2050 13692572 YP_006769109.1 CDS O3M_07235 NC_018650.1 1495371 1495487 D hypothetical protein 1495371..1495487 Escherichia coli O104:H4 str. 2009EL-2050 13692573 YP_006769110.1 CDS O3M_07240 NC_018650.1 1495575 1496801 D COG3192 Ethanolamine utilization protein; ethanolamine utilization protein EutH 1495575..1496801 Escherichia coli O104:H4 str. 2009EL-2050 13692574 YP_006769111.1 CDS eutA NC_018650.1 1496798 1498201 D COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition; reactivating factor for ethanolamine ammonia lyase 1496798..1498201 Escherichia coli O104:H4 str. 2009EL-2050 13692575 YP_006769112.1 CDS O3M_07250 NC_018650.1 1498213 1499574 D COG4303 Ethanolamine ammonia-lyase, large subunit; ethanolamine ammonia lyase large subunit 1498213..1499574 Escherichia coli O104:H4 str. 2009EL-2050 13692576 YP_006769113.1 CDS O3M_07255 NC_018650.1 1499595 1500482 D COG4302 Ethanolamine ammonia-lyase, small subunit; ethanolamine ammonia-lyase small subunit 1499595..1500482 Escherichia coli O104:H4 str. 2009EL-2050 13692577 YP_006769114.1 CDS O3M_07260 NC_018650.1 1500492 1501151 D COG4816 Ethanolamine utilization protein; ethanolamine utilization protein EutL 1500492..1501151 Escherichia coli O104:H4 str. 2009EL-2050 13692578 YP_006769115.1 CDS O3M_07265 NC_018650.1 1501164 1501664 D COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; carboxysome structural protein EutK 1501164..1501664 Escherichia coli O104:H4 str. 2009EL-2050 13692579 YP_006769116.1 CDS O3M_07270 NC_018650.1 1501710 1502762 D COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator EutR 1501710..1502762 Escherichia coli O104:H4 str. 2009EL-2050 13692580 YP_006769117.1 CDS O3M_07275 NC_018650.1 1502768 1503667 R COG0408 Coproporphyrinogen III oxidase; coproporphyrinogen III oxidase complement(1502768..1503667) Escherichia coli O104:H4 str. 2009EL-2050 13692581 YP_006769118.1 CDS O3M_07280 NC_018650.1 1503671 1504540 R COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-l-alanine amidase I complement(1503671..1504540) Escherichia coli O104:H4 str. 2009EL-2050 13692582 YP_006769119.1 CDS O3M_07285 NC_018650.1 1504754 1505179 D COG0456 Acetyltransferases; acetyltransferase 1504754..1505179 Escherichia coli O104:H4 str. 2009EL-2050 13692583 YP_006769120.1 CDS O3M_07290 NC_018650.1 1505166 1505615 D inner membrane protein 1505166..1505615 Escherichia coli O104:H4 str. 2009EL-2050 13692584 YP_006769121.1 CDS O3M_07295 NC_018650.1 1505676 1506251 D RpoE-regulated lipoprotein 1505676..1506251 Escherichia coli O104:H4 str. 2009EL-2050 13692585 YP_006769122.1 CDS O3M_07300 NC_018650.1 1506347 1507246 D COG2837 Predicted iron-dependent peroxidase; dyp-type peroxidase family protein 1506347..1507246 Escherichia coli O104:H4 str. 2009EL-2050 13692586 YP_006769123.1 CDS O3M_07305 NC_018650.1 1507302 1508606 R COG1680 Beta-lactamase class C and other penicillin binding proteins; periplasmic esterase complement(1507302..1508606) Escherichia coli O104:H4 str. 2009EL-2050 13692587 YP_006769124.1 CDS murP NC_018650.1 1508611 1510035 R COG1264 Phosphotransferase system IIB components; PTS system N-acetylmuramic acid transporter subunit IIBC complement(1508611..1510035) Escherichia coli O104:H4 str. 2009EL-2050 13692588 YP_006769125.1 CDS murQ NC_018650.1 1510039 1510935 R COG2103 Predicted sugar phosphate isomerase; N-acetylmuramic acid 6-phosphate etherase complement(1510039..1510935) Escherichia coli O104:H4 str. 2009EL-2050 13692589 YP_006769126.1 CDS O3M_07320 NC_018650.1 1511099 1511956 D COG1737 Transcriptional regulators; transcriptional regulator MurR 1511099..1511956 Escherichia coli O104:H4 str. 2009EL-2050 13692590 YP_006769127.1 CDS O3M_07325 NC_018650.1 1512085 1512876 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 1512085..1512876 Escherichia coli O104:H4 str. 2009EL-2050 13692591 YP_006769128.1 CDS O3M_07330 NC_018650.1 1513047 1514063 D COG4150 ABC-type sulfate transport system, periplasmic component; thiosulfate transporter subunit 1513047..1514063 Escherichia coli O104:H4 str. 2009EL-2050 13692592 YP_006769129.1 CDS O3M_07335 NC_018650.1 1514063 1514896 D COG0555 ABC-type sulfate transport system, permease component; sulfate/thiosulfate transporter subunit 1514063..1514896 Escherichia coli O104:H4 str. 2009EL-2050 13692593 YP_006769130.1 CDS cysW NC_018650.1 1514896 1515771 D COG4208 ABC-type sulfate transport system, permease component; sulfate/thiosulfate transporter permease subunit 1514896..1515771 Escherichia coli O104:H4 str. 2009EL-2050 13692594 YP_006769131.1 CDS O3M_07345 NC_018650.1 1515761 1516858 D COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; sulfate/thiosulfate transporter subunit 1515761..1516858 Escherichia coli O104:H4 str. 2009EL-2050 13692595 YP_006769132.1 CDS cysM NC_018650.1 1516992 1517903 D COG0031 Cysteine synthase; cysteine synthase B 1516992..1517903 Escherichia coli O104:H4 str. 2009EL-2050 13692596 YP_006769133.1 CDS O3M_07355 NC_018650.1 1517906 1518274 R hypothetical protein complement(1517906..1518274) Escherichia coli O104:H4 str. 2009EL-2050 13692597 YP_006769134.1 CDS pdxK NC_018650.1 1518379 1519230 D COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase 1518379..1519230 Escherichia coli O104:H4 str. 2009EL-2050 13692598 YP_006769135.1 CDS O3M_07365 NC_018650.1 1519272 1519781 R COG2190 Phosphotransferase system IIA components; PTS system glucose-specific transporter complement(1519272..1519781) Escherichia coli O104:H4 str. 2009EL-2050 13692599 YP_006769136.1 CDS O3M_07370 NC_018650.1 1519822 1521549 R COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); phosphoenolpyruvate-protein phosphotransferase complement(1519822..1521549) Escherichia coli O104:H4 str. 2009EL-2050 13692600 YP_006769137.1 CDS O3M_07375 NC_018650.1 1521594 1521851 R COG1925 Phosphotransferase system, HPr-related proteins; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr complement(1521594..1521851) Escherichia coli O104:H4 str. 2009EL-2050 13692601 YP_006769138.1 CDS O3M_07380 NC_018650.1 1522235 1523206 R COG0031 Cysteine synthase; cysteine synthase A complement(1522235..1523206) Escherichia coli O104:H4 str. 2009EL-2050 13692602 YP_006769139.1 CDS O3M_07385 NC_018650.1 1523391 1524152 R COG2981 Uncharacterized protein involved in cysteine biosynthesis; sulfate transport protein CysZ complement(1523391..1524152) Escherichia coli O104:H4 str. 2009EL-2050 13692603 YP_006769140.1 CDS O3M_07390 NC_018650.1 1524382 1525368 D COG3115 Cell division protein; cell division protein ZipA 1524382..1525368 Escherichia coli O104:H4 str. 2009EL-2050 13692604 YP_006769141.1 CDS ligA NC_018650.1 1525439 1527454 D COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase LigA 1525439..1527454 Escherichia coli O104:H4 str. 2009EL-2050 13692605 YP_006769142.1 CDS O3M_07400 NC_018650.1 1527456 1527674 D COG3530 Uncharacterized protein conserved in bacteria; hypothetical protein 1527456..1527674 Escherichia coli O104:H4 str. 2009EL-2050 13692606 YP_006769143.1 CDS O3M_07405 NC_018650.1 1527671 1528669 R COG0385 Predicted Na+-dependent transporter; hypothetical protein complement(1527671..1528669) Escherichia coli O104:H4 str. 2009EL-2050 13692607 YP_006769144.1 CDS O3M_07410 NC_018650.1 1528759 1529685 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 1528759..1529685 Escherichia coli O104:H4 str. 2009EL-2050 13692608 YP_006769145.1 CDS O3M_07415 NC_018650.1 1529724 1530488 R hypothetical protein complement(1529724..1530488) Escherichia coli O104:H4 str. 2009EL-2050 13692609 YP_006769146.1 CDS O3M_07420 NC_018650.1 1530737 1531570 D COG0005 Purine nucleoside phosphorylase; purine nucleoside phosphorylase 1530737..1531570 Escherichia coli O104:H4 str. 2009EL-2050 13692610 YP_006769147.1 CDS O3M_07425 NC_018650.1 1531630 1532886 D COG0477 Permeases of the major facilitator superfamily; xanthosine transporter 1531630..1532886 Escherichia coli O104:H4 str. 2009EL-2050 13692611 YP_006769148.1 CDS O3M_07430 NC_018650.1 1532939 1533097 D hypothetical protein 1532939..1533097 Escherichia coli O104:H4 str. 2009EL-2050 13692612 YP_006769149.1 CDS O3M_07435 NC_018650.1 1533138 1534022 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator XapR 1533138..1534022 Escherichia coli O104:H4 str. 2009EL-2050 13692613 YP_006769150.1 CDS gltX NC_018650.1 1534943 1536358 D COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-tRNA synthetase 1534943..1536358 Escherichia coli O104:H4 str. 2009EL-2050 13692618 YP_006769151.1 CDS O3M_07445 NC_018650.1 1536410 1536802 R COG1396 Predicted transcriptional regulators; DNA-binding transcriptional regulator complement(1536410..1536802) Escherichia coli O104:H4 str. 2009EL-2050 13692619 YP_006769152.1 CDS O3M_07450 NC_018650.1 1536804 1537163 R hypothetical protein complement(1536804..1537163) Escherichia coli O104:H4 str. 2009EL-2050 13692620 YP_006769153.1 CDS O3M_07455 NC_018650.1 1537782 1539971 D COG2199 FOG: GGDEF domain; diguanylate cyclase 1537782..1539971 Escherichia coli O104:H4 str. 2009EL-2050 13692623 YP_006769154.1 CDS O3M_07460 NC_018650.1 1540021 1541223 R COG1972 Nucleoside permease; nucleoside (except guanosine) transporter NupC complement(1540021..1541223) Escherichia coli O104:H4 str. 2009EL-2050 13692624 YP_006769155.1 CDS O3M_07465 NC_018650.1 1541559 1542797 D COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; manganese transport protein MntH 1541559..1542797 Escherichia coli O104:H4 str. 2009EL-2050 13692625 YP_006769156.1 CDS O3M_07470 NC_018650.1 1542938 1543264 R hypothetical protein complement(1542938..1543264) Escherichia coli O104:H4 str. 2009EL-2050 13692626 YP_006769157.1 CDS O3M_07475 NC_018650.1 1543379 1544635 R COG1284 Uncharacterized conserved protein; ion channel protein complement(1543379..1544635) Escherichia coli O104:H4 str. 2009EL-2050 13692627 YP_006769158.1 CDS glk NC_018650.1 1544839 1545804 D COG0837 Glucokinase; glucokinase 1544839..1545804 Escherichia coli O104:H4 str. 2009EL-2050 13692628 YP_006769159.1 CDS O3M_07485 NC_018650.1 1546023 1546349 D COG1445 Phosphotransferase system fructose-specific component IIB; PTS system transporter subunit IIB 1546023..1546349 Escherichia coli O104:H4 str. 2009EL-2050 13692629 YP_006769160.1 CDS O3M_07490 NC_018650.1 1546371 1547618 D COG1299 Phosphotransferase system, fructose-specific IIC component; fructose-like permease IIC component 1546371..1547618 Escherichia coli O104:H4 str. 2009EL-2050 13692630 YP_006769161.1 CDS O3M_07495 NC_018650.1 1547633 1548718 D COG0006 Xaa-Pro aminopeptidase; aminopeptidase 1547633..1548718 Escherichia coli O104:H4 str. 2009EL-2050 13692631 YP_006769162.1 CDS O3M_07500 NC_018650.1 1548718 1549755 D COG1363 Cellulase M and related proteins; exoaminopeptidase 1548718..1549755 Escherichia coli O104:H4 str. 2009EL-2050 13692632 YP_006769163.1 CDS O3M_07505 NC_018650.1 1549780 1552275 D Hpr component; enzyme I component; enzyme IIA component; COG1925 Phosphotransferase system, HPr-related proteins; PTS system transporter multiphosphoryl transfer protein 1549780..1552275 Escherichia coli O104:H4 str. 2009EL-2050 13692633 YP_006769164.1 CDS O3M_07510 NC_018650.1 1552278 1553135 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding protein, ARAC-type complement(1552278..1553135) Escherichia coli O104:H4 str. 2009EL-2050 13692634 YP_006769165.1 CDS O3M_07515 NC_018650.1 1553148 1553882 R COG3279 Response regulator of the LytR/AlgR family; hypothetical protein complement(1553148..1553882) Escherichia coli O104:H4 str. 2009EL-2050 13692635 YP_006769166.1 CDS O3M_07520 NC_018650.1 1553897 1555594 R COG3275 Putative regulator of cell autolysis; hypothetical protein complement(1553897..1555594) Escherichia coli O104:H4 str. 2009EL-2050 13692636 YP_006769167.1 CDS O3M_07525 NC_018650.1 1555971 1557209 D COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase 1555971..1557209 Escherichia coli O104:H4 str. 2009EL-2050 13693054 YP_006769168.1 CDS O3M_07530 NC_018650.1 1557701 1558621 R COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis palmitoleoyl acyltransferase complement(1557701..1558621) Escherichia coli O104:H4 str. 2009EL-2050 13693055 YP_006769169.1 CDS O3M_07535 NC_018650.1 1558974 1559216 D inner membrane protein 1558974..1559216 Escherichia coli O104:H4 str. 2009EL-2050 13693056 YP_006769170.1 CDS O3M_07540 NC_018650.1 1559293 1559568 R lipoprotein complement(1559293..1559568) Escherichia coli O104:H4 str. 2009EL-2050 13693057 YP_006769171.1 CDS O3M_07545 NC_018650.1 1559864 1560496 D hypothetical protein 1559864..1560496 Escherichia coli O104:H4 str. 2009EL-2050 13693058 YP_006769172.1 CDS O3M_07550 NC_018650.1 1561009 1562259 D COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; formyl-coenzyme A transferase 1561009..1562259 Escherichia coli O104:H4 str. 2009EL-2050 13693059 YP_006769173.1 CDS O3M_07555 NC_018650.1 1562313 1564007 D COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; oxalyl-CoA decarboxylase 1562313..1564007 Escherichia coli O104:H4 str. 2009EL-2050 13693060 YP_006769174.1 CDS O3M_07560 NC_018650.1 1564077 1565021 D COG0679 Predicted permeases; transporter YfdV 1564077..1565021 Escherichia coli O104:H4 str. 2009EL-2050 13693061 YP_006769175.1 CDS O3M_07565 NC_018650.1 1565095 1566240 D COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; CoA-transferase 1565095..1566240 Escherichia coli O104:H4 str. 2009EL-2050 13693062 YP_006769176.1 CDS O3M_07570 NC_018650.1 1566296 1569889 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; hybrid sensory histidine kinase in two-component regulatory system with EvgA complement(1566296..1569889) Escherichia coli O104:H4 str. 2009EL-2050 13693063 YP_006769177.1 CDS O3M_07575 NC_018650.1 1569894 1570508 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator EvgA complement(1569894..1570508) Escherichia coli O104:H4 str. 2009EL-2050 13693064 YP_006769178.1 CDS O3M_07580 NC_018650.1 1570924 1572087 D COG1566 Multidrug resistance efflux pump; EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component 1570924..1572087 Escherichia coli O104:H4 str. 2009EL-2050 13693065 YP_006769179.1 CDS O3M_07585 NC_018650.1 1572087 1573625 D COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein Y 1572087..1573625 Escherichia coli O104:H4 str. 2009EL-2050 13693066 YP_006769180.1 CDS O3M_07590 NC_018650.1 1573733 1575061 R COG3048 D-serine dehydratase; D-serine dehydratase complement(1573733..1575061) Escherichia coli O104:H4 str. 2009EL-2050 13693067 YP_006769181.1 CDS O3M_07595 NC_018650.1 1575079 1575297 R COG2610 H+/gluconate symporter and related permeases; permease DsdX complement(1575079..1575297) Escherichia coli O104:H4 str. 2009EL-2050 13693068 YP_006769182.1 CDS O3M_07600 NC_018650.1 1575528 1576523 D COG1609 Transcriptional regulators; sucrose operon repressor 1575528..1576523 Escherichia coli O104:H4 str. 2009EL-2050 13693069 YP_006769183.1 CDS O3M_07605 NC_018650.1 1576531 1577964 R COG1621 Beta-fructosidases (levanase/invertase); sucrose-6-phosphate hydrolase complement(1576531..1577964) Escherichia coli O104:H4 str. 2009EL-2050 13693070 YP_006769184.1 CDS O3M_07610 NC_018650.1 1578180 1579094 D COG0524 Sugar kinases, ribokinase family; aminoimidazole riboside kinase 1578180..1579094 Escherichia coli O104:H4 str. 2009EL-2050 13693071 YP_006769185.1 CDS lacY NC_018650.1 1579166 1580413 D COG0477 Permeases of the major facilitator superfamily; galactoside permease 1579166..1580413 Escherichia coli O104:H4 str. 2009EL-2050 13693072 YP_006769186.1 CDS O3M_07620 NC_018650.1 1580943 1581143 R hypothetical protein complement(1580943..1581143) Escherichia coli O104:H4 str. 2009EL-2050 13693073 YP_006769187.1 CDS O3M_07625 NC_018650.1 1581275 1581454 R hypothetical protein complement(1581275..1581454) Escherichia coli O104:H4 str. 2009EL-2050 13693074 YP_006769188.1 CDS O3M_07635 NC_018650.1 1582177 1582386 R prophage protein complement(1582177..1582386) Escherichia coli O104:H4 str. 2009EL-2050 13693075 YP_006769189.1 CDS O3M_07640 NC_018650.1 1582749 1583420 R COG0529 Adenylylsulfate kinase and related kinases; hypothetical protein complement(1582749..1583420) Escherichia coli O104:H4 str. 2009EL-2050 13693076 YP_006769190.1 CDS O3M_07645 NC_018650.1 1583417 1583584 R hypothetical protein complement(1583417..1583584) Escherichia coli O104:H4 str. 2009EL-2050 13693077 YP_006769191.1 CDS O3M_07650 NC_018650.1 1583581 1583871 R hypothetical protein complement(1583581..1583871) Escherichia coli O104:H4 str. 2009EL-2050 13693078 YP_006769192.1 CDS O3M_07655 NC_018650.1 1583882 1584178 R Anti-RecBCD protein 2 complement(1583882..1584178) Escherichia coli O104:H4 str. 2009EL-2050 13693079 YP_006769193.1 CDS O3M_07660 NC_018650.1 1584202 1584585 R hypothetical protein complement(1584202..1584585) Escherichia coli O104:H4 str. 2009EL-2050 13693080 YP_006769194.1 CDS O3M_07665 NC_018650.1 1584585 1585190 R essential recombination function protein Erf; DNA single-strand annealing protein complement(1584585..1585190) Escherichia coli O104:H4 str. 2009EL-2050 13693081 YP_006769195.1 CDS O3M_07670 NC_018650.1 1585201 1585371 R hypothetical protein complement(1585201..1585371) Escherichia coli O104:H4 str. 2009EL-2050 13693082 YP_006769196.1 CDS O3M_07675 NC_018650.1 1585447 1585599 R host killing protein complement(1585447..1585599) Escherichia coli O104:H4 str. 2009EL-2050 13693083 YP_006769197.1 CDS O3M_07680 NC_018650.1 1585584 1585715 R regulatory protein CIII complement(1585584..1585715) Escherichia coli O104:H4 str. 2009EL-2050 13693084 YP_006769198.1 CDS O3M_07685 NC_018650.1 1585945 1586220 D COG3677 Transposase and inactivated derivatives; InsA 1585945..1586220 Escherichia coli O104:H4 str. 2009EL-2050 13693085 YP_006769199.1 CDS O3M_07690 NC_018650.1 1586139 1586642 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 1586139..1586642 Escherichia coli O104:H4 str. 2009EL-2050 13693086 YP_006769200.1 CDS O3M_07695 NC_018650.1 1586660 1588372 D hypothetical protein 1586660..1588372 Escherichia coli O104:H4 str. 2009EL-2050 13693087 YP_006769201.1 CDS O3M_07700 NC_018650.1 1588443 1590353 R COG1835 Predicted acyltransferases; hypothetical protein complement(1588443..1590353) Escherichia coli O104:H4 str. 2009EL-2050 13693088 YP_006769202.1 CDS O3M_07705 NC_018650.1 1590582 1591739 R CPS-53 (KpLE1) prophage; COG0582 Integrase; prophage CPS-53 integrase complement(1590582..1591739) Escherichia coli O104:H4 str. 2009EL-2050 13693089 YP_006769203.1 CDS O3M_07710 NC_018650.1 1592051 1592983 R COG2116 Formate/nitrite family of transporters; hypothetical protein complement(1592051..1592983) Escherichia coli O104:H4 str. 2009EL-2050 13693091 YP_006769204.1 CDS O3M_07715 NC_018650.1 1593277 1594032 D COG2853 Surface lipoprotein; ABC transporter outer membrane lipoprotein 1593277..1594032 Escherichia coli O104:H4 str. 2009EL-2050 13693092 YP_006769205.1 CDS O3M_07720 NC_018650.1 1594214 1595272 R hypothetical protein complement(1594214..1595272) Escherichia coli O104:H4 str. 2009EL-2050 13693093 YP_006769206.1 CDS O3M_07725 NC_018650.1 1595638 1596978 R COG2067 Long-chain fatty acid transport protein; long-chain fatty acid outer membrane transporter complement(1595638..1596978) Escherichia coli O104:H4 str. 2009EL-2050 13693094 YP_006769207.1 CDS O3M_07730 NC_018650.1 1597350 1597634 D COG3691 Uncharacterized protein conserved in bacteria; hypothetical protein 1597350..1597634 Escherichia coli O104:H4 str. 2009EL-2050 13693095 YP_006769208.1 CDS fadI NC_018650.1 1597814 1599124 D COG0183 Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase 1597814..1599124 Escherichia coli O104:H4 str. 2009EL-2050 13693096 YP_006769209.1 CDS fadJ NC_018650.1 1599124 1601268 D COG1024 Enoyl-CoA hydratase/carnithine racemase; multifunctional fatty acid oxidation complex subunit alpha 1599124..1601268 Escherichia coli O104:H4 str. 2009EL-2050 13693097 YP_006769210.1 CDS O3M_07745 NC_018650.1 1601471 1601956 D COG2062 Phosphohistidine phosphatase SixA; phosphohistidine phosphatase 1601471..1601956 Escherichia coli O104:H4 str. 2009EL-2050 13693098 YP_006769211.1 CDS O3M_07750 NC_018650.1 1602631 1603194 D fimbrial-like protein 1602631..1603194 Escherichia coli O104:H4 str. 2009EL-2050 13693099 YP_006769212.1 CDS O3M_07755 NC_018650.1 1603276 1605918 D COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein StfC 1603276..1605918 Escherichia coli O104:H4 str. 2009EL-2050 13693100 YP_006769213.1 CDS O3M_07760 NC_018650.1 1605938 1606690 D COG3121 P pilus assembly protein, chaperone PapD; chaperone 1605938..1606690 Escherichia coli O104:H4 str. 2009EL-2050 13693101 YP_006769214.1 CDS O3M_07765 NC_018650.1 1606707 1607213 D minor fimbrial subunit 1606707..1607213 Escherichia coli O104:H4 str. 2009EL-2050 13693102 YP_006769215.1 CDS O3M_07770 NC_018650.1 1607210 1607680 D fimbrial subunit protein 1607210..1607680 Escherichia coli O104:H4 str. 2009EL-2050 13693103 YP_006769216.1 CDS O3M_07775 NC_018650.1 1607677 1608201 D COG3539 P pilus assembly protein, pilin FimA; fimbrial subunit protein 1607677..1608201 Escherichia coli O104:H4 str. 2009EL-2050 13693104 YP_006769217.1 CDS O3M_07780 NC_018650.1 1608293 1609060 D hypothetical protein 1608293..1609060 Escherichia coli O104:H4 str. 2009EL-2050 13693105 YP_006769218.1 CDS O3M_07785 NC_018650.1 1609287 1610267 D COG3547 Transposase and inactivated derivatives; IS621 transposase 1609287..1610267 Escherichia coli O104:H4 str. 2009EL-2050 13693106 YP_006769219.1 CDS O3M_07790 NC_018650.1 1610461 1611012 R COG2840 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1610461..1611012) Escherichia coli O104:H4 str. 2009EL-2050 13693107 YP_006769220.1 CDS O3M_07795 NC_018650.1 1611178 1612110 D COG2890 Methylase of polypeptide chain release factors; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1611178..1612110 Escherichia coli O104:H4 str. 2009EL-2050 13693108 YP_006769221.1 CDS O3M_07800 NC_018650.1 1612145 1613230 D COG0082 Chorismate synthase; chorismate synthase 1612145..1613230 Escherichia coli O104:H4 str. 2009EL-2050 13693109 YP_006769222.1 CDS mepA NC_018650.1 1613234 1614058 D COG3770 Murein endopeptidase; penicillin-insensitive murein endopeptidase 1613234..1614058 Escherichia coli O104:H4 str. 2009EL-2050 13693110 YP_006769223.1 CDS O3M_07810 NC_018650.1 1614058 1614867 D COG0730 Predicted permeases; hypothetical protein 1614058..1614867 Escherichia coli O104:H4 str. 2009EL-2050 13693111 YP_006769224.1 CDS O3M_07815 NC_018650.1 1614867 1615415 D COG3101 Uncharacterized protein conserved in bacteria; hypothetical protein 1614867..1615415 Escherichia coli O104:H4 str. 2009EL-2050 13693112 YP_006769225.1 CDS O3M_07820 NC_018650.1 1615449 1615727 D hypothetical protein 1615449..1615727 Escherichia coli O104:H4 str. 2009EL-2050 13693113 YP_006769226.1 CDS mnmC NC_018650.1 1615848 1617854 R COG4121 Uncharacterized conserved protein; bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase complement(1615848..1617854) Escherichia coli O104:H4 str. 2009EL-2050 13693114 YP_006769227.1 CDS O3M_07830 NC_018650.1 1618013 1619233 D COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-ACP synthase 1618013..1619233 Escherichia coli O104:H4 str. 2009EL-2050 13693115 YP_006769228.1 CDS O3M_07835 NC_018650.1 1619517 1620695 D COG0477 Permeases of the major facilitator superfamily; transporter 1619517..1620695 Escherichia coli O104:H4 str. 2009EL-2050 13693116 YP_006769229.1 CDS flk NC_018650.1 1620692 1621687 R flagella biosynthesis regulator complement(1620692..1621687) Escherichia coli O104:H4 str. 2009EL-2050 13693117 YP_006769230.1 CDS O3M_07845 NC_018650.1 1621786 1622922 D COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; erythronate-4-phosphate dehydrogenase PdxB 1621786..1622922 Escherichia coli O104:H4 str. 2009EL-2050 13693118 YP_006769231.1 CDS O3M_07850 NC_018650.1 1622988 1624001 D COG0136 Aspartate-semialdehyde dehydrogenase; semialdehyde dehydrogenase 1622988..1624001 Escherichia coli O104:H4 str. 2009EL-2050 13693119 YP_006769232.1 CDS truA NC_018650.1 1624001 1624813 D COG0101 Pseudouridylate synthase; tRNA pseudouridine synthase A 1624001..1624813 Escherichia coli O104:H4 str. 2009EL-2050 13693120 YP_006769233.1 CDS O3M_07860 NC_018650.1 1624896 1625555 D COG0586 Uncharacterized membrane-associated protein; hypothetical protein 1624896..1625555 Escherichia coli O104:H4 str. 2009EL-2050 13693121 YP_006769234.1 CDS O3M_07865 NC_018650.1 1625711 1626625 D COG0777 Acetyl-CoA carboxylase beta subunit; acetyl-CoA carboxylase subunit beta 1625711..1626625 Escherichia coli O104:H4 str. 2009EL-2050 13693122 YP_006769235.1 CDS O3M_07870 NC_018650.1 1626695 1627963 D COG0285 Folylpolyglutamate synthase; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 1626695..1627963 Escherichia coli O104:H4 str. 2009EL-2050 13693123 YP_006769236.1 CDS O3M_07875 NC_018650.1 1627953 1628615 D COG3147 Uncharacterized protein conserved in bacteria; cell division protein DedD 1627953..1628615 Escherichia coli O104:H4 str. 2009EL-2050 13693124 YP_006769237.1 CDS O3M_07880 NC_018650.1 1628874 1629362 D COG1286 Uncharacterized membrane protein, required for colicin V production; colicin V production protein 1628874..1629362 Escherichia coli O104:H4 str. 2009EL-2050 13693125 YP_006769238.1 CDS O3M_07885 NC_018650.1 1629399 1630916 D COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; amidophosphoribosyltransferase 1629399..1630916 Escherichia coli O104:H4 str. 2009EL-2050 13693126 YP_006769239.1 CDS O3M_07890 NC_018650.1 1631011 1631580 D COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1631011..1631580 Escherichia coli O104:H4 str. 2009EL-2050 13693127 YP_006769240.1 CDS O3M_07895 NC_018650.1 1631846 1632628 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; lysine/arginine/ornithine ABC transporter substrate-binding protein 1631846..1632628 Escherichia coli O104:H4 str. 2009EL-2050 13693128 YP_006769241.1 CDS O3M_07900 NC_018650.1 1632849 1633631 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; histidine ABC transporter substrate-binding protein HisJ 1632849..1633631 Escherichia coli O104:H4 str. 2009EL-2050 13693129 YP_006769242.1 CDS O3M_07905 NC_018650.1 1633721 1634407 D COG4215 ABC-type arginine transport system, permease component; histidine/lysine/arginine/ornithine ABC transporter permease HisQ 1633721..1634407 Escherichia coli O104:H4 str. 2009EL-2050 13693130 YP_006769243.1 CDS O3M_07910 NC_018650.1 1634404 1635120 D COG4160 ABC-type arginine/histidine transport system, permease component; histidine/lysine/arginine/ornithine ABC transporter permease HisM 1634404..1635120 Escherichia coli O104:H4 str. 2009EL-2050 13693131 YP_006769244.1 CDS O3M_07915 NC_018650.1 1635128 1635901 D COG4598 ABC-type histidine transport system, ATPase component; histidine/lysine/arginine/ornithine transporter subunit 1635128..1635901 Escherichia coli O104:H4 str. 2009EL-2050 13693132 YP_006769245.1 CDS O3M_07920 NC_018650.1 1636098 1637000 D transposase 1636098..1637000 Escherichia coli O104:H4 str. 2009EL-2050 13693133 YP_006769246.1 CDS O3M_07925 NC_018650.1 1637048 1637941 R NAD(P)-binding Rossmann-fold domain; COG1090 Predicted nucleoside-diphosphate sugar epimerase; NAD dependent epimerase/dehydratase family protein complement(1637048..1637941) Escherichia coli O104:H4 str. 2009EL-2050 13693134 YP_006769247.1 CDS folX NC_018650.1 1637962 1638324 R COG1539 Dihydroneopterin aldolase; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase complement(1637962..1638324) Escherichia coli O104:H4 str. 2009EL-2050 13693135 YP_006769248.1 CDS O3M_07935 NC_018650.1 1638381 1639028 R COG0625 Glutathione S-transferase; GSH-dependent disulfide bond oxidoreductase complement(1638381..1639028) Escherichia coli O104:H4 str. 2009EL-2050 13693136 YP_006769249.1 CDS O3M_07940 NC_018650.1 1639164 1639808 D COG0625 Glutathione S-transferase; glutathione S-transferase 1639164..1639808 Escherichia coli O104:H4 str. 2009EL-2050 13693137 YP_006769250.1 CDS O3M_07945 NC_018650.1 1639864 1640415 D COG0622 Predicted phosphoesterase; phosphodiesterase 1639864..1640415 Escherichia coli O104:H4 str. 2009EL-2050 13693138 YP_006769251.1 CDS O3M_07950 NC_018650.1 1640473 1641015 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase YfcD 1640473..1641015 Escherichia coli O104:H4 str. 2009EL-2050 13693139 YP_006769252.1 CDS O3M_07955 NC_018650.1 1641048 1642568 R COG1288 Predicted membrane protein; hypothetical protein complement(1641048..1642568) Escherichia coli O104:H4 str. 2009EL-2050 13693140 YP_006769253.1 CDS O3M_07960 NC_018650.1 1642758 1644902 R COG0857 BioD-like N-terminal domain of phosphotransacetylase; phosphate acetyltransferase complement(1642758..1644902) Escherichia coli O104:H4 str. 2009EL-2050 13693141 YP_006769254.1 CDS O3M_07965 NC_018650.1 1644977 1646179 R COG0282 Acetate kinase; acetate kinase A/propionate kinase 2 complement(1644977..1646179) Escherichia coli O104:H4 str. 2009EL-2050 13693142 YP_006769255.1 CDS O3M_07970 NC_018650.1 1646317 1646448 D hypothetical protein 1646317..1646448 Escherichia coli O104:H4 str. 2009EL-2050 13693143 YP_006769256.1 CDS O3M_07975 NC_018650.1 1646517 1646972 D COG3092 Uncharacterized protein conserved in bacteria; hypothetical protein 1646517..1646972 Escherichia coli O104:H4 str. 2009EL-2050 13693144 YP_006769257.1 CDS O3M_07980 NC_018650.1 1647055 1647549 D COG3013 Uncharacterized conserved protein; hypothetical protein 1647055..1647549 Escherichia coli O104:H4 str. 2009EL-2050 13693145 YP_006769258.1 CDS O3M_07985 NC_018650.1 1647560 1648210 D COG0637 Predicted phosphatase/phosphohexomutase; phosphatase 1647560..1648210 Escherichia coli O104:H4 str. 2009EL-2050 13693146 YP_006769259.1 CDS O3M_07990 NC_018650.1 1648297 1650129 D COG0471 Di- and tricarboxylate transporters; transporter 1648297..1650129 Escherichia coli O104:H4 str. 2009EL-2050 13693147 YP_006769260.1 CDS O3M_07995 NC_018650.1 1650188 1650787 R COG1896 Predicted hydrolases of HD superfamily; 5'-nucleotidase complement(1650188..1650787) Escherichia coli O104:H4 str. 2009EL-2050 13693148 YP_006769261.1 CDS O3M_08000 NC_018650.1 1650871 1652088 R COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase AlaT complement(1650871..1652088) Escherichia coli O104:H4 str. 2009EL-2050 13693149 YP_006769262.1 CDS O3M_08005 NC_018650.1 1653008 1653946 D COG0583 Transcriptional regulator; DNA-binding transcriptional repressor LrhA 1653008..1653946 Escherichia coli O104:H4 str. 2009EL-2050 13693150 YP_006769263.1 CDS O3M_08010 NC_018650.1 1654577 1655020 D COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); NADH:ubiquinone oxidoreductase subunit A 1654577..1655020 Escherichia coli O104:H4 str. 2009EL-2050 13693151 YP_006769264.1 CDS O3M_08015 NC_018650.1 1655036 1655698 D COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; NADH dehydrogenase subunit B 1655036..1655698 Escherichia coli O104:H4 str. 2009EL-2050 13693152 YP_006769265.1 CDS O3M_08020 NC_018650.1 1655792 1657594 D COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; NADH:ubiquinone oxidoreductase subunit C/D 1655792..1657594 Escherichia coli O104:H4 str. 2009EL-2050 13693153 YP_006769266.1 CDS O3M_08025 NC_018650.1 1657597 1658097 D COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; NADH dehydrogenase subunit E 1657597..1658097 Escherichia coli O104:H4 str. 2009EL-2050 13693154 YP_006769267.1 CDS O3M_08030 NC_018650.1 1658094 1659431 D COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; NADH dehydrogenase I subunit F 1658094..1659431 Escherichia coli O104:H4 str. 2009EL-2050 13693155 YP_006769268.1 CDS O3M_08035 NC_018650.1 1659484 1662210 D COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); NADH dehydrogenase subunit G 1659484..1662210 Escherichia coli O104:H4 str. 2009EL-2050 13693156 YP_006769269.1 CDS O3M_08040 NC_018650.1 1662207 1663184 D COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); NADH:ubiquinone oxidoreductase subunit H 1662207..1663184 Escherichia coli O104:H4 str. 2009EL-2050 13693157 YP_006769270.1 CDS O3M_08045 NC_018650.1 1663199 1663741 D COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); NADH dehydrogenase subunit I 1663199..1663741 Escherichia coli O104:H4 str. 2009EL-2050 13693158 YP_006769271.1 CDS O3M_08050 NC_018650.1 1663753 1664307 D COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); NADH:ubiquinone oxidoreductase subunit J 1663753..1664307 Escherichia coli O104:H4 str. 2009EL-2050 13693159 YP_006769272.1 CDS O3M_08055 NC_018650.1 1664304 1664606 D COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); NADH:ubiquinone oxidoreductase subunit K 1664304..1664606 Escherichia coli O104:H4 str. 2009EL-2050 13693160 YP_006769273.1 CDS O3M_08060 NC_018650.1 1664603 1666444 D COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; NADH:ubiquinone oxidoreductase subunit L 1664603..1666444 Escherichia coli O104:H4 str. 2009EL-2050 13693161 YP_006769274.1 CDS O3M_08065 NC_018650.1 1666608 1668137 D COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); NADH:ubiquinone oxidoreductase subunit M 1666608..1668137 Escherichia coli O104:H4 str. 2009EL-2050 13693162 YP_006769275.1 CDS O3M_08070 NC_018650.1 1668144 1669601 D COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); NADH:ubiquinone oxidoreductase subunit N 1668144..1669601 Escherichia coli O104:H4 str. 2009EL-2050 13693163 YP_006769276.1 CDS O3M_08075 NC_018650.1 1669668 1670171 R hypothetical protein complement(1669668..1670171) Escherichia coli O104:H4 str. 2009EL-2050 13693164 YP_006769277.1 CDS O3M_08080 NC_018650.1 1670297 1670476 R COG2234 Predicted aminopeptidases; Zn-dependent exopeptidase complement(1670297..1670476) Escherichia coli O104:H4 str. 2009EL-2050 13693165 YP_006769278.1 CDS O3M_08095 NC_018650.1 1672701 1673618 R COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; ribonuclease Z complement(1672701..1673618) Escherichia coli O104:H4 str. 2009EL-2050 13693166 YP_006769279.1 CDS O3M_08100 NC_018650.1 1673683 1674144 D COG2153 Predicted acyltransferase; acyltransferase 1673683..1674144 Escherichia coli O104:H4 str. 2009EL-2050 13693167 YP_006769280.1 CDS O3M_08105 NC_018650.1 1674199 1674504 D COG4575 Uncharacterized conserved protein; hypothetical protein 1674199..1674504 Escherichia coli O104:H4 str. 2009EL-2050 13693168 YP_006769281.1 CDS O3M_08110 NC_018650.1 1674583 1675878 D COG1169 Isochorismate synthase; menaquinone-specific isochorismate synthase 1674583..1675878 Escherichia coli O104:H4 str. 2009EL-2050 13693169 YP_006769282.1 CDS O3M_08115 NC_018650.1 1675967 1677637 D COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1675967..1677637 Escherichia coli O104:H4 str. 2009EL-2050 13693170 YP_006769283.1 CDS O3M_08120 NC_018650.1 1677634 1678392 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase 1677634..1678392 Escherichia coli O104:H4 str. 2009EL-2050 13693171 YP_006769284.1 CDS O3M_08125 NC_018650.1 1678407 1679264 D COG0447 Dihydroxynaphthoic acid synthase; dihydroxynaphthoic acid synthetase 1678407..1679264 Escherichia coli O104:H4 str. 2009EL-2050 13693172 YP_006769285.1 CDS O3M_08130 NC_018650.1 1679264 1680226 D COG1441 O-succinylbenzoate synthase; O-succinylbenzoate synthase 1679264..1680226 Escherichia coli O104:H4 str. 2009EL-2050 13693173 YP_006769286.1 CDS O3M_08135 NC_018650.1 1680223 1681578 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; O-succinylbenzoic acid--CoA ligase 1680223..1681578 Escherichia coli O104:H4 str. 2009EL-2050 13693174 YP_006769287.1 CDS O3M_08140 NC_018650.1 1681688 1681954 D COG1601 Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain; signal transduction protein PmrD 1681688..1681954 Escherichia coli O104:H4 str. 2009EL-2050 13693175 YP_006769288.1 CDS O3M_08145 NC_018650.1 1681948 1682334 R 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF complement(1681948..1682334) Escherichia coli O104:H4 str. 2009EL-2050 13693176 YP_006769289.1 CDS O3M_08150 NC_018650.1 1682334 1682669 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE complement(1682334..1682669) Escherichia coli O104:H4 str. 2009EL-2050 13693177 YP_006769290.1 CDS arnT NC_018650.1 1682666 1684318 R COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family; 4-amino-4-deoxy-L-arabinose transferase complement(1682666..1684318) Escherichia coli O104:H4 str. 2009EL-2050 13693178 YP_006769291.1 CDS O3M_08160 NC_018650.1 1684318 1685208 R COG0726 Predicted xylanase/chitin deacetylase; 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase ArnD complement(1684318..1685208) Escherichia coli O104:H4 str. 2009EL-2050 13693179 YP_006769292.1 CDS O3M_08165 NC_018650.1 1685205 1687187 R COG0223 Methionyl-tRNA formyltransferase; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase complement(1685205..1687187) Escherichia coli O104:H4 str. 2009EL-2050 13693180 YP_006769293.1 CDS O3M_08170 NC_018650.1 1687187 1688155 R COG0463 Glycosyltransferases involved in cell wall biogenesis; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase complement(1687187..1688155) Escherichia coli O104:H4 str. 2009EL-2050 13693181 YP_006769294.1 CDS O3M_08175 NC_018650.1 1688159 1689298 R COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase complement(1688159..1689298) Escherichia coli O104:H4 str. 2009EL-2050 13693182 YP_006769295.1 CDS O3M_08180 NC_018650.1 1689606 1690208 D lipopolysaccharide core heptose(II)-phosphate phosphatase 1689606..1690208 Escherichia coli O104:H4 str. 2009EL-2050 13693183 YP_006769296.1 CDS O3M_08185 NC_018650.1 1690247 1690672 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; nucleoside triphosphatase NudI complement(1690247..1690672) Escherichia coli O104:H4 str. 2009EL-2050 13693184 YP_006769297.1 CDS O3M_08190 NC_018650.1 1690951 1691493 D outer membrane porin protein 1690951..1691493 Escherichia coli O104:H4 str. 2009EL-2050 13693185 YP_006769298.1 CDS O3M_08195 NC_018650.1 1691593 1692795 D COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; hypothetical protein 1691593..1692795 Escherichia coli O104:H4 str. 2009EL-2050 13693186 YP_006769299.1 CDS O3M_08200 NC_018650.1 1692931 1693320 D COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; 2-keto-3-deoxy-L-rhamnonate aldolase 1692931..1693320 Escherichia coli O104:H4 str. 2009EL-2050 13693187 YP_006769300.1 CDS O3M_08205 NC_018650.1 1693361 1694263 R COG5464 Uncharacterized conserved protein; hypothetical protein complement(1693361..1694263) Escherichia coli O104:H4 str. 2009EL-2050 13693188 YP_006769301.1 CDS glpC NC_018650.1 1694457 1695647 R COG0247 Fe-S oxidoreductase; sn-glycerol-3-phosphate dehydrogenase subunit C complement(1694457..1695647) Escherichia coli O104:H4 str. 2009EL-2050 13693189 YP_006769302.1 CDS O3M_08215 NC_018650.1 1695644 1696903 R COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(1695644..1696903) Escherichia coli O104:H4 str. 2009EL-2050 13693190 YP_006769303.1 CDS glpA NC_018650.1 1696893 1698521 R COG0578 Glycerol-3-phosphate dehydrogenase; sn-glycerol-3-phosphate dehydrogenase subunit A complement(1696893..1698521) Escherichia coli O104:H4 str. 2009EL-2050 13693191 YP_006769304.1 CDS glpT NC_018650.1 1698794 1700152 D COG2271 Sugar phosphate permease; sn-glycerol-3-phosphate transporter 1698794..1700152 Escherichia coli O104:H4 str. 2009EL-2050 13693192 YP_006769305.1 CDS glpQ NC_018650.1 1700157 1701233 D COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphodiester phosphodiesterase 1700157..1701233 Escherichia coli O104:H4 str. 2009EL-2050 13693193 YP_006769306.1 CDS O3M_08235 NC_018650.1 1701275 1701481 R hypothetical protein complement(1701275..1701481) Escherichia coli O104:H4 str. 2009EL-2050 13693194 YP_006769307.1 CDS O3M_08240 NC_018650.1 1701662 1702642 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 1701662..1702642 Escherichia coli O104:H4 str. 2009EL-2050 13693195 YP_006769308.1 CDS O3M_08245 NC_018650.1 1702896 1703546 D hypothetical protein 1702896..1703546 Escherichia coli O104:H4 str. 2009EL-2050 13693196 YP_006769309.1 CDS O3M_08250 NC_018650.1 1703600 1703854 R COG0633 Ferredoxin; 2Fe-2S ferredoxin complement(1703600..1703854) Escherichia coli O104:H4 str. 2009EL-2050 13693197 YP_006769310.1 CDS nrdB NC_018650.1 1703854 1704984 R COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta complement(1703854..1704984) Escherichia coli O104:H4 str. 2009EL-2050 13693198 YP_006769311.1 CDS O3M_08260 NC_018650.1 1705073 1707358 R COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha complement(1705073..1707358) Escherichia coli O104:H4 str. 2009EL-2050 13693199 YP_006769312.1 CDS O3M_08265 NC_018650.1 1708054 1711788 D COG3468 Type V secretory pathway, adhesin AidA; adhesin 1708054..1711788 Escherichia coli O104:H4 str. 2009EL-2050 13693200 YP_006769313.1 CDS O3M_08270 NC_018650.1 1711916 1712638 R COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase; bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase complement(1711916..1712638) Escherichia coli O104:H4 str. 2009EL-2050 13693201 YP_006769314.1 CDS O3M_08275 NC_018650.1 1712785 1715412 D COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA gyrase subunit A 1712785..1715412 Escherichia coli O104:H4 str. 2009EL-2050 13693202 YP_006769315.1 CDS O3M_08280 NC_018650.1 1715561 1717249 D COG4685 Uncharacterized protein conserved in bacteria; hypothetical protein 1715561..1717249 Escherichia coli O104:H4 str. 2009EL-2050 13693203 YP_006769316.1 CDS O3M_08285 NC_018650.1 1717246 1717869 D COG3234 Uncharacterized protein conserved in bacteria; hypothetical protein 1717246..1717869 Escherichia coli O104:H4 str. 2009EL-2050 13693204 YP_006769317.1 CDS O3M_08290 NC_018650.1 1717803 1722407 D COG2373 Large extracellular alpha-helical protein; alpha-2-macroglobulin family protein 1717803..1722407 Escherichia coli O104:H4 str. 2009EL-2050 13693205 YP_006769318.1 CDS O3M_08295 NC_018650.1 1722408 1724057 D COG5445 Predicted secreted protein; hypothetical protein 1722408..1724057 Escherichia coli O104:H4 str. 2009EL-2050 13693206 YP_006769319.1 CDS O3M_08300 NC_018650.1 1724062 1724838 D COG4676 Uncharacterized protein conserved in bacteria; hypothetical protein 1724062..1724838 Escherichia coli O104:H4 str. 2009EL-2050 13693207 YP_006769320.1 CDS O3M_08305 NC_018650.1 1725113 1727962 D COG0642 Signal transduction histidine kinase; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 1725113..1727962 Escherichia coli O104:H4 str. 2009EL-2050 13693208 YP_006769321.1 CDS O3M_08310 NC_018650.1 1728162 1728812 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator RcsB complement(1728162..1728812) Escherichia coli O104:H4 str. 2009EL-2050 13693209 YP_006769322.1 CDS O3M_08315 NC_018650.1 1728829 1731501 R COG0642 Signal transduction histidine kinase; phosphotransfer intermediate protein in two-component regulatory system with RcsBC complement(1728829..1731501) Escherichia coli O104:H4 str. 2009EL-2050 13693210 YP_006769323.1 CDS O3M_08320 NC_018650.1 1732240 1733343 D COG3203 Outer membrane protein (porin); outer membrane porin protein C 1732240..1733343 Escherichia coli O104:H4 str. 2009EL-2050 13693211 YP_006769324.1 CDS O3M_08325 NC_018650.1 1733455 1734510 D COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; thiamine biosynthesis lipoprotein ApbE 1733455..1734510 Escherichia coli O104:H4 str. 2009EL-2050 13693212 YP_006769325.1 CDS O3M_08330 NC_018650.1 1734584 1735648 D COG2169 Adenosine deaminase; bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase 1734584..1735648 Escherichia coli O104:H4 str. 2009EL-2050 13693213 YP_006769326.1 CDS O3M_08335 NC_018650.1 1735648 1736298 D COG3145 Alkylated DNA repair protein; alpha-ketoglutarate-dependent dioxygenase AlkB 1735648..1736298 Escherichia coli O104:H4 str. 2009EL-2050 13693214 YP_006769327.1 CDS O3M_08340 NC_018650.1 1736374 1738017 D COG4615 ABC-type siderophore export system, fused ATPase and permease components; multidrug transporter membrane protein/ATP-binding component 1736374..1738017 Escherichia coli O104:H4 str. 2009EL-2050 13693215 YP_006769328.1 CDS O3M_08345 NC_018650.1 1738235 1739881 D COG0579 Predicted dehydrogenase; malate:quinone oxidoreductase 1738235..1739881 Escherichia coli O104:H4 str. 2009EL-2050 13693216 YP_006769329.1 CDS O3M_08350 NC_018650.1 1740030 1740518 R COG4574 Serine protease inhibitor ecotin; ecotin complement(1740030..1740518) Escherichia coli O104:H4 str. 2009EL-2050 13693217 YP_006769330.1 CDS O3M_08355 NC_018650.1 1740653 1740826 R COG1626 Neutral trehalase; hypothetical protein complement(1740653..1740826) Escherichia coli O104:H4 str. 2009EL-2050 13693218 YP_006769331.1 CDS O3M_08360 NC_018650.1 1740926 1741420 D COG1145 Ferredoxin; ferredoxin-type protein 1740926..1741420 Escherichia coli O104:H4 str. 2009EL-2050 13693219 YP_006769332.1 CDS O3M_08365 NC_018650.1 1741410 1741673 D COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase; assembly protein for periplasmic nitrate reductase 1741410..1741673 Escherichia coli O104:H4 str. 2009EL-2050 13693220 YP_006769333.1 CDS O3M_08370 NC_018650.1 1741670 1744156 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; nitrate reductase catalytic subunit 1741670..1744156 Escherichia coli O104:H4 str. 2009EL-2050 13693221 YP_006769334.1 CDS napG NC_018650.1 1744163 1744858 D COG1145 Ferredoxin; quinol dehydrogenase periplasmic component 1744163..1744858 Escherichia coli O104:H4 str. 2009EL-2050 13693222 YP_006769335.1 CDS napH NC_018650.1 1744845 1745708 D COG0348 Polyferredoxin; quinol dehydrogenase membrane component 1744845..1745708 Escherichia coli O104:H4 str. 2009EL-2050 13693223 YP_006769336.1 CDS napB NC_018650.1 1745705 1746154 D COG3043 Nitrate reductase cytochrome c-type subunit; nitrate reductase cytochrome C550 subunit 1745705..1746154 Escherichia coli O104:H4 str. 2009EL-2050 13693224 YP_006769337.1 CDS O3M_08390 NC_018650.1 1746164 1746766 D COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; cytochrome c-type protein NapC 1746164..1746766 Escherichia coli O104:H4 str. 2009EL-2050 13693225 YP_006769338.1 CDS O3M_08395 NC_018650.1 1746785 1747402 D COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component; cytochrome c biogenesis protein CcmA 1746785..1747402 Escherichia coli O104:H4 str. 2009EL-2050 13693226 YP_006769339.1 CDS O3M_08400 NC_018650.1 1747399 1748061 D COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component; Heme exporter protein B 1747399..1748061 Escherichia coli O104:H4 str. 2009EL-2050 13693227 YP_006769340.1 CDS O3M_08405 NC_018650.1 1748103 1748840 D COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; heme exporter protein C 1748103..1748840 Escherichia coli O104:H4 str. 2009EL-2050 13693228 YP_006769341.1 CDS O3M_08410 NC_018650.1 1748837 1749046 D COG3114 Heme exporter protein D; cytochrome c biogenesis protein CcmD 1748837..1749046 Escherichia coli O104:H4 str. 2009EL-2050 13693229 YP_006769342.1 CDS O3M_08415 NC_018650.1 1749043 1749522 D COG2332 Cytochrome c-type biogenesis protein CcmE; cytochrome c-type biogenesis protein CcmE 1749043..1749522 Escherichia coli O104:H4 str. 2009EL-2050 13693230 YP_006769343.1 CDS O3M_08420 NC_018650.1 1749519 1751462 D COG1138 Cytochrome c biogenesis factor; heme lyase, CcmF subunit 1749519..1751462 Escherichia coli O104:H4 str. 2009EL-2050 13693231 YP_006769344.1 CDS O3M_08425 NC_018650.1 1751459 1752016 D COG0526 Thiol-disulfide isomerase and thioredoxins; thiol:disulfide interchange protein DsbE 1751459..1752016 Escherichia coli O104:H4 str. 2009EL-2050 13693232 YP_006769345.1 CDS O3M_08430 NC_018650.1 1752013 1753065 D COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; heme lyase, CcmH subunit 1752013..1753065 Escherichia coli O104:H4 str. 2009EL-2050 13693233 YP_006769346.1 CDS O3M_08435 NC_018650.1 1753100 1753747 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator NarP complement(1753100..1753747) Escherichia coli O104:H4 str. 2009EL-2050 13693234 YP_006769347.1 CDS O3M_08440 NC_018650.1 1754148 1756433 D COG3468 Type V secretory pathway, adhesin AidA; autotransporter 1754148..1756433 Escherichia coli O104:H4 str. 2009EL-2050 13693235 YP_006769348.1 CDS O3M_08445 NC_018650.1 1756446 1756658 D autotransporter outer membrane protein 1756446..1756658 Escherichia coli O104:H4 str. 2009EL-2050 13693236 YP_006769349.1 CDS O3M_08450 NC_018650.1 1756912 1758672 R COG3083 Predicted hydrolase of alkaline phosphatase superfamily; hydrolase, inner membrane complement(1756912..1758672) Escherichia coli O104:H4 str. 2009EL-2050 13693238 YP_006769350.1 CDS O3M_08455 NC_018650.1 1758692 1758919 R COG3082 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1758692..1758919) Escherichia coli O104:H4 str. 2009EL-2050 13693239 YP_006769351.1 CDS O3M_08460 NC_018650.1 1759101 1760108 D COG3081 Nucleoid-associated protein; nucleoid-associated protein NdpA 1759101..1760108 Escherichia coli O104:H4 str. 2009EL-2050 13693240 YP_006769352.1 CDS O3M_08465 NC_018650.1 1760247 1760531 R COG1825 Ribosomal protein L25 (general stress protein Ctc); 50S ribosomal protein L25 complement(1760247..1760531) Escherichia coli O104:H4 str. 2009EL-2050 13693241 YP_006769353.1 CDS O3M_08470 NC_018650.1 1760656 1762416 R COG1061 DNA or RNA helicases of superfamily II; nucleic acid ATP-dependent helicase complement(1760656..1762416) Escherichia coli O104:H4 str. 2009EL-2050 13693242 YP_006769354.1 CDS O3M_08475 NC_018650.1 1762565 1763260 D COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA pseudouridylate synthase A 1762565..1763260 Escherichia coli O104:H4 str. 2009EL-2050 13693243 YP_006769355.1 CDS O3M_08480 NC_018650.1 1763288 1764478 D COG0477 Permeases of the major facilitator superfamily; bicyclomycin/multidrug efflux system protein 1763288..1764478 Escherichia coli O104:H4 str. 2009EL-2050 13693244 YP_006769356.1 CDS O3M_08485 NC_018650.1 1764811 1765155 D hypothetical protein 1764811..1765155 Escherichia coli O104:H4 str. 2009EL-2050 13693245 YP_006769357.1 CDS O3M_08490 NC_018650.1 1765159 1766748 R COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; microcin C ABC transporter ATP-binding protein YejF complement(1765159..1766748) Escherichia coli O104:H4 str. 2009EL-2050 13693246 YP_006769358.1 CDS O3M_08495 NC_018650.1 1766750 1767775 R COG4239 ABC-type uncharacterized transport system, permease component; microcin C ABC transporter permease complement(1766750..1767775) Escherichia coli O104:H4 str. 2009EL-2050 13693247 YP_006769359.1 CDS O3M_08500 NC_018650.1 1767775 1768869 R COG4174 ABC-type uncharacterized transport system, permease component; microcin C ABC transporter permease YejB complement(1767775..1768869) Escherichia coli O104:H4 str. 2009EL-2050 13693248 YP_006769360.1 CDS O3M_08505 NC_018650.1 1768870 1770684 R periplasmic-binding component of ABC superfamily transporter; COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide transporter subunit complement(1768870..1770684) Escherichia coli O104:H4 str. 2009EL-2050 13693249 YP_006769361.1 CDS O3M_08510 NC_018650.1 1770766 1772322 R COG2200 FOG: EAL domain; phage resistance protein complement(1770766..1772322) Escherichia coli O104:H4 str. 2009EL-2050 13693250 YP_006769362.1 CDS spr NC_018650.1 1772503 1773069 R COG0791 Cell wall-associated hydrolases (invasion-associated proteins); outer membrane lipoprotein complement(1772503..1773069) Escherichia coli O104:H4 str. 2009EL-2050 13693251 YP_006769363.1 CDS O3M_08520 NC_018650.1 1773481 1774194 R COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein complement(1773481..1774194) Escherichia coli O104:H4 str. 2009EL-2050 13693252 YP_006769364.1 CDS O3M_08525 NC_018650.1 1774233 1775219 R COG0523 Putative GTPases (G3E family); hypothetical protein complement(1774233..1775219) Escherichia coli O104:H4 str. 2009EL-2050 13693253 YP_006769365.1 CDS O3M_08530 NC_018650.1 1775337 1776803 R COG0246 Mannitol-1-phosphate/altronate dehydrogenases; sugar dehydrogenase, NAD-dependent complement(1775337..1776803) Escherichia coli O104:H4 str. 2009EL-2050 13693254 YP_006769366.1 CDS O3M_08535 NC_018650.1 1777026 1777598 R COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); elongation factor P complement(1777026..1777598) Escherichia coli O104:H4 str. 2009EL-2050 13693255 YP_006769367.1 CDS O3M_08540 NC_018650.1 1777753 1778007 D COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 1777753..1778007 Escherichia coli O104:H4 str. 2009EL-2050 13693256 YP_006769368.1 CDS O3M_08545 NC_018650.1 1778004 1779185 R COG0477 Permeases of the major facilitator superfamily; sugar efflux transporter B complement(1778004..1779185) Escherichia coli O104:H4 str. 2009EL-2050 13693257 YP_006769369.1 CDS O3M_08550 NC_018650.1 1779553 1780683 D COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; PTS system fructose-specific transporter subunit IIA/HPr protein 1779553..1780683 Escherichia coli O104:H4 str. 2009EL-2050 13693258 YP_006769370.1 CDS fruK NC_018650.1 1780683 1781621 D COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); 1-phosphofructokinase 1780683..1781621 Escherichia coli O104:H4 str. 2009EL-2050 13693259 YP_006769371.1 CDS O3M_08560 NC_018650.1 1781638 1783329 D COG3925 N-terminal domain of the phosphotransferase system fructose-specific component IIB; PTS system fructose-specific transporter subunit IIBC 1781638..1783329 Escherichia coli O104:H4 str. 2009EL-2050 13693260 YP_006769372.1 CDS O3M_08565 NC_018650.1 1783753 1784694 D COG0524 Sugar kinases, ribokinase family; pseudouridine kinase 1783753..1784694 Escherichia coli O104:H4 str. 2009EL-2050 13693261 YP_006769373.1 CDS O3M_08570 NC_018650.1 1784682 1785620 D COG2313 Uncharacterized enzyme involved in pigment biosynthesis; hypothetical protein 1784682..1785620 Escherichia coli O104:H4 str. 2009EL-2050 13693262 YP_006769374.1 CDS O3M_08575 NC_018650.1 1785714 1786964 D COG1972 Nucleoside permease; sodium/proton nucleoside transporter 1785714..1786964 Escherichia coli O104:H4 str. 2009EL-2050 13693263 YP_006769375.1 CDS O3M_08580 NC_018650.1 1787032 1787691 R COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; DNA-binding transcriptional activator YeiL complement(1787032..1787691) Escherichia coli O104:H4 str. 2009EL-2050 13693264 YP_006769376.1 CDS rihB NC_018650.1 1787860 1788801 D COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase 2 1787860..1788801 Escherichia coli O104:H4 str. 2009EL-2050 13693265 YP_006769377.1 CDS O3M_08590 NC_018650.1 1788901 1790151 D COG1972 Nucleoside permease; nucleoside transporter 1788901..1790151 Escherichia coli O104:H4 str. 2009EL-2050 13693266 YP_006769378.1 CDS O3M_08595 NC_018650.1 1790207 1791295 R COG2771 DNA-binding HTH domain-containing proteins; kinase complement(1790207..1791295) Escherichia coli O104:H4 str. 2009EL-2050 13693267 YP_006769379.1 CDS O3M_08600 NC_018650.1 1791299 1792156 R COG0648 Endonuclease IV; endonuclease IV complement(1791299..1792156) Escherichia coli O104:H4 str. 2009EL-2050 13693268 YP_006769380.1 CDS O3M_08605 NC_018650.1 1792230 1793279 R COG2855 Predicted membrane protein; hypothetical protein complement(1792230..1793279) Escherichia coli O104:H4 str. 2009EL-2050 13693269 YP_006769381.1 CDS O3M_08610 NC_018650.1 1793378 1794259 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 1793378..1794259 Escherichia coli O104:H4 str. 2009EL-2050 13693270 YP_006769382.1 CDS O3M_08615 NC_018650.1 1794464 1795933 D COG0833 Amino acid transporters; lysine transporter 1794464..1795933 Escherichia coli O104:H4 str. 2009EL-2050 13693271 YP_006769383.1 CDS O3M_08620 NC_018650.1 1796226 1798217 D COG4771 Outer membrane receptor for ferrienterochelin and colicins; catecholate siderophore receptor CirA 1796226..1798217 Escherichia coli O104:H4 str. 2009EL-2050 13693272 YP_006769384.1 CDS O3M_08625 NC_018650.1 1798249 1799085 R COG0627 Predicted esterase; esterase complement(1798249..1799085) Escherichia coli O104:H4 str. 2009EL-2050 13693273 YP_006769385.1 CDS folE NC_018650.1 1799343 1800011 D COG0302 GTP cyclohydrolase I; GTP cyclohydrolase I 1799343..1800011 Escherichia coli O104:H4 str. 2009EL-2050 13693274 YP_006769386.1 CDS O3M_08635 NC_018650.1 1800028 1801185 D COG2311 Predicted membrane protein; hypothetical protein 1800028..1801185 Escherichia coli O104:H4 str. 2009EL-2050 13693275 YP_006769387.1 CDS O3M_08640 NC_018650.1 1801327 1802367 D COG1609 Transcriptional regulators; DNA-binding transcriptional regulator GalS 1801327..1802367 Escherichia coli O104:H4 str. 2009EL-2050 13693276 YP_006769388.1 CDS O3M_08645 NC_018650.1 1802647 1803645 D COG1879 ABC-type sugar transport system, periplasmic component; methyl-galactoside ABC transporter substrate-binding protein MglB 1802647..1803645 Escherichia coli O104:H4 str. 2009EL-2050 13693277 YP_006769389.1 CDS O3M_08650 NC_018650.1 1803706 1805226 D COG1129 ABC-type sugar transport system, ATPase component; galactose/methyl galaxtoside transporter ATP-binding protein 1803706..1805226 Escherichia coli O104:H4 str. 2009EL-2050 13693278 YP_006769390.1 CDS mglC NC_018650.1 1805242 1806252 D COG4211 ABC-type glucose/galactose transport system, permease component; beta-methylgalactoside transporter inner membrane protein 1805242..1806252 Escherichia coli O104:H4 str. 2009EL-2050 13693279 YP_006769391.1 CDS O3M_08660 NC_018650.1 1806323 1807558 R COG0167 Dihydroorotate dehydrogenase; dihydropyrimidine dehydrogenase subunit B complement(1806323..1807558) Escherichia coli O104:H4 str. 2009EL-2050 13693280 YP_006769392.1 CDS O3M_08665 NC_018650.1 1807552 1808790 R COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; dihydropyrimidine dehydrogenase subunit A complement(1807552..1808790) Escherichia coli O104:H4 str. 2009EL-2050 13693281 YP_006769393.1 CDS O3M_08670 NC_018650.1 1809109 1809348 R hypothetical protein complement(1809109..1809348) Escherichia coli O104:H4 str. 2009EL-2050 13693282 YP_006769394.1 CDS O3M_08675 NC_018650.1 1809351 1810070 R COG2949 Uncharacterized membrane protein; vancomycin high temperature exclusion protein complement(1809351..1810070) Escherichia coli O104:H4 str. 2009EL-2050 13693283 YP_006769395.1 CDS O3M_08680 NC_018650.1 1810220 1811104 R COG0295 Cytidine deaminase; cytidine deaminase complement(1810220..1811104) Escherichia coli O104:H4 str. 2009EL-2050 13693284 YP_006769396.1 CDS O3M_08685 NC_018650.1 1811234 1811929 R COG1346 Putative effector of murein hydrolase; hypothetical protein complement(1811234..1811929) Escherichia coli O104:H4 str. 2009EL-2050 13693285 YP_006769397.1 CDS O3M_08690 NC_018650.1 1811926 1812324 R COG1380 Putative effector of murein hydrolase LrgA; hypothetical protein complement(1811926..1812324) Escherichia coli O104:H4 str. 2009EL-2050 13693286 YP_006769398.1 CDS O3M_08695 NC_018650.1 1812563 1813510 D COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase C 1812563..1813510 Escherichia coli O104:H4 str. 2009EL-2050 13693287 YP_006769399.1 CDS O3M_08700 NC_018650.1 1813883 1813966 R hypothetical protein complement(1813883..1813966) Escherichia coli O104:H4 str. 2009EL-2050 13693288 YP_006769400.1 CDS O3M_08705 NC_018650.1 1814190 1815626 D COG1538 Outer membrane protein; multidrug resistance outer membrane protein MdtQ 1814190..1815626 Escherichia coli O104:H4 str. 2009EL-2050 13693289 YP_006769401.1 CDS O3M_08710 NC_018650.1 1815679 1816440 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1815679..1816440 Escherichia coli O104:H4 str. 2009EL-2050 13693290 YP_006769402.1 CDS O3M_08715 NC_018650.1 1816570 1817148 R COG0586 Uncharacterized membrane-associated protein; inner membrane protein complement(1816570..1817148) Escherichia coli O104:H4 str. 2009EL-2050 13693291 YP_006769403.1 CDS O3M_08720 NC_018650.1 1817318 1817905 D inner membrane protein YohC 1817318..1817905 Escherichia coli O104:H4 str. 2009EL-2050 13693292 YP_006769404.1 CDS pbpG NC_018650.1 1818079 1819011 D COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine endopeptidase 1818079..1819011 Escherichia coli O104:H4 str. 2009EL-2050 13693293 YP_006769405.1 CDS O3M_08730 NC_018650.1 1819049 1820764 R COG0277 FAD/FMN-containing dehydrogenases; D-lactate dehydrogenase complement(1819049..1820764) Escherichia coli O104:H4 str. 2009EL-2050 13693294 YP_006769406.1 CDS O3M_08735 NC_018650.1 1820960 1823257 D COG1472 Beta-glucosidase-related glycosidases; beta-D-glucoside glucohydrolase 1820960..1823257 Escherichia coli O104:H4 str. 2009EL-2050 13693295 YP_006769407.1 CDS O3M_08740 NC_018650.1 1823468 1824385 D COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); transporter subunit 1823468..1824385 Escherichia coli O104:H4 str. 2009EL-2050 13693296 YP_006769408.1 CDS O3M_08745 NC_018650.1 1824392 1825549 D COG1174 ABC-type proline/glycine betaine transport systems, permease component; transporter subunit 1824392..1825549 Escherichia coli O104:H4 str. 2009EL-2050 13693297 YP_006769409.1 CDS O3M_08750 NC_018650.1 1825542 1826468 D COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; ABC transporter ATP-binding protein 1825542..1826468 Escherichia coli O104:H4 str. 2009EL-2050 13693298 YP_006769410.1 CDS O3M_08755 NC_018650.1 1826473 1827204 D COG1174 ABC-type proline/glycine betaine transport systems, permease component; quaternare amine family ABC transporter permease 1826473..1827204 Escherichia coli O104:H4 str. 2009EL-2050 13693299 YP_006769411.1 CDS O3M_08760 NC_018650.1 1827185 1827292 R hypothetical protein complement(1827185..1827292) Escherichia coli O104:H4 str. 2009EL-2050 13693300 YP_006769412.1 CDS O3M_08765 NC_018650.1 1827352 1828083 R COG0789 Predicted transcriptional regulators; transcriptional regulator MirA complement(1827352..1828083) Escherichia coli O104:H4 str. 2009EL-2050 13693301 YP_006769413.1 CDS O3M_08770 NC_018650.1 1828305 1829990 D COG3275 Putative regulator of cell autolysis; sensory kinase in two-component system with YehT 1828305..1829990 Escherichia coli O104:H4 str. 2009EL-2050 13693302 YP_006769414.1 CDS O3M_08775 NC_018650.1 1829987 1830706 D COG3279 Response regulator of the LytR/AlgR family; two-component response-regulatory protein YehT 1829987..1830706 Escherichia coli O104:H4 str. 2009EL-2050 13693303 YP_006769415.1 CDS O3M_08780 NC_018650.1 1830753 1831223 D COG4807 Uncharacterized protein conserved in bacteria; hypothetical protein 1830753..1831223 Escherichia coli O104:H4 str. 2009EL-2050 13693304 YP_006769416.1 CDS O3M_08785 NC_018650.1 1831264 1831725 R COG4808 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1831264..1831725) Escherichia coli O104:H4 str. 2009EL-2050 13693305 YP_006769417.1 CDS O3M_08790 NC_018650.1 1831850 1833850 R hypothetical protein complement(1831850..1833850) Escherichia coli O104:H4 str. 2009EL-2050 13693306 YP_006769418.1 CDS O3M_08795 NC_018650.1 1833847 1834983 R hypothetical protein complement(1833847..1834983) Escherichia coli O104:H4 str. 2009EL-2050 13693307 YP_006769419.1 CDS O3M_08800 NC_018650.1 1834976 1837255 R hypothetical protein complement(1834976..1837255) Escherichia coli O104:H4 str. 2009EL-2050 13693308 YP_006769420.1 CDS O3M_08805 NC_018650.1 1837266 1838354 R COG0714 MoxR-like ATPases; transporter subunit complement(1837266..1838354) Escherichia coli O104:H4 str. 2009EL-2050 13693309 YP_006769421.1 CDS O3M_08810 NC_018650.1 1839395 1839484 D hypothetical protein 1839395..1839484 Escherichia coli O104:H4 str. 2009EL-2050 13693310 YP_006769422.1 CDS O3M_08815 NC_018650.1 1839972 1843604 R hypothetical protein complement(1839972..1843604) Escherichia coli O104:H4 str. 2009EL-2050 13693311 YP_006769423.1 CDS O3M_08820 NC_018650.1 1843614 1847408 R COG3831 Uncharacterized conserved protein; hypothetical protein complement(1843614..1847408) Escherichia coli O104:H4 str. 2009EL-2050 13693312 YP_006769424.1 CDS metG NC_018650.1 1847549 1849582 R COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase complement(1847549..1849582) Escherichia coli O104:H4 str. 2009EL-2050 13693313 YP_006769425.1 CDS O3M_08830 NC_018650.1 1849714 1850823 D COG0489 ATPases involved in chromosome partitioning; antiporter inner membrane protein 1849714..1850823 Escherichia coli O104:H4 str. 2009EL-2050 13693314 YP_006769426.1 CDS O3M_08835 NC_018650.1 1851086 1851367 D hypothetical protein 1851086..1851367 Escherichia coli O104:H4 str. 2009EL-2050 13693315 YP_006769427.1 CDS O3M_08840 NC_018650.1 1851660 1852202 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like protein 1851660..1852202 Escherichia coli O104:H4 str. 2009EL-2050 13693316 YP_006769428.1 CDS O3M_08845 NC_018650.1 1852283 1852957 D COG3121 P pilus assembly protein, chaperone PapD; membrane-associated pilin chaperone 1852283..1852957 Escherichia coli O104:H4 str. 2009EL-2050 13693317 YP_006769429.1 CDS O3M_08850 NC_018650.1 1852973 1855453 D COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 1852973..1855453 Escherichia coli O104:H4 str. 2009EL-2050 13693318 YP_006769430.1 CDS O3M_08855 NC_018650.1 1855484 1856134 D fimbrial-like adhesin protein StcD 1855484..1856134 Escherichia coli O104:H4 str. 2009EL-2050 13693319 YP_006769431.1 CDS O3M_08860 NC_018650.1 1856185 1856460 D COG3677 Transposase and inactivated derivatives; InsA 1856185..1856460 Escherichia coli O104:H4 str. 2009EL-2050 13693320 YP_006769432.1 CDS O3M_08865 NC_018650.1 1856379 1856882 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 1856379..1856882 Escherichia coli O104:H4 str. 2009EL-2050 13693321 YP_006769433.1 CDS O3M_08870 NC_018650.1 1856984 1857280 D fimbrial-like adhesin protein StcD 1856984..1857280 Escherichia coli O104:H4 str. 2009EL-2050 13693322 YP_006769434.1 CDS O3M_08875 NC_018650.1 1857362 1857700 R COG5455 Predicted integral membrane protein; hypothetical protein complement(1857362..1857700) Escherichia coli O104:H4 str. 2009EL-2050 13693323 YP_006769435.1 CDS O3M_08880 NC_018650.1 1857919 1858743 R COG2215 ABC-type uncharacterized transport system, permease component; nickel/cobalt efflux protein RcnA complement(1857919..1858743) Escherichia coli O104:H4 str. 2009EL-2050 13693324 YP_006769436.1 CDS O3M_08885 NC_018650.1 1858864 1859136 D COG1937 Uncharacterized protein conserved in bacteria; transcriptional repressor RcnR to maintain nickel and cobalt homeostasis 1858864..1859136 Escherichia coli O104:H4 str. 2009EL-2050 13693325 YP_006769437.1 CDS O3M_08890 NC_018650.1 1859359 1860147 D COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 1859359..1860147 Escherichia coli O104:H4 str. 2009EL-2050 13693326 YP_006769438.1 CDS O3M_08895 NC_018650.1 1860144 1860944 D COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase 1860144..1860944 Escherichia coli O104:H4 str. 2009EL-2050 13693327 YP_006769439.1 CDS O3M_08900 NC_018650.1 1861009 1861827 D COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); hydrolase 1861009..1861827 Escherichia coli O104:H4 str. 2009EL-2050 13693328 YP_006769440.1 CDS O3M_08905 NC_018650.1 1861879 1862625 D COG2188 Transcriptional regulators; GntR family transcriptional regulator 1861879..1862625 Escherichia coli O104:H4 str. 2009EL-2050 13693329 YP_006769441.1 CDS O3M_08910 NC_018650.1 1862599 1863564 R COG0524 Sugar kinases, ribokinase family; kinase complement(1862599..1863564) Escherichia coli O104:H4 str. 2009EL-2050 13693330 YP_006769442.1 CDS O3M_08915 NC_018650.1 1863561 1864565 R COG1397 ADP-ribosylglycohydrolase; (phospho)hydrolase complement(1863561..1864565) Escherichia coli O104:H4 str. 2009EL-2050 13693331 YP_006769443.1 CDS O3M_08920 NC_018650.1 1864562 1865839 R COG0477 Permeases of the major facilitator superfamily; nucleoside transporter complement(1864562..1865839) Escherichia coli O104:H4 str. 2009EL-2050 13693332 YP_006769444.1 CDS O3M_08925 NC_018650.1 1866096 1867148 D COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes; fructose-bisphosphate aldolase 1866096..1867148 Escherichia coli O104:H4 str. 2009EL-2050 13693333 YP_006769445.1 CDS gatY NC_018650.1 1867458 1868312 D COG0191 Fructose/tagatose bisphosphate aldolase; tagatose-bisphosphate aldolase 1867458..1868312 Escherichia coli O104:H4 str. 2009EL-2050 13693334 YP_006769446.1 CDS O3M_08945 NC_018650.1 1869608 1870060 D COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system galactitol-specific transporter subunit IIA 1869608..1870060 Escherichia coli O104:H4 str. 2009EL-2050 13693335 YP_006769447.1 CDS O3M_08950 NC_018650.1 1870091 1870375 D COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB 1870091..1870375 Escherichia coli O104:H4 str. 2009EL-2050 13693336 YP_006769448.1 CDS O3M_08955 NC_018650.1 1870379 1871734 D COG3775 Phosphotransferase system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1870379..1871734 Escherichia coli O104:H4 str. 2009EL-2050 13693337 YP_006769449.1 CDS O3M_08960 NC_018650.1 1871782 1872822 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; galactitol-1-phosphate dehydrogenase 1871782..1872822 Escherichia coli O104:H4 str. 2009EL-2050 13693338 YP_006769450.1 CDS O3M_08965 NC_018650.1 1872928 1873701 D COG1349 Transcriptional regulators of sugar metabolism; galactitol utilization operon repressor 1872928..1873701 Escherichia coli O104:H4 str. 2009EL-2050 13693339 YP_006769451.1 CDS O3M_08970 NC_018650.1 1873783 1874682 R COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; lipid kinase complement(1873783..1874682) Escherichia coli O104:H4 str. 2009EL-2050 13693340 YP_006769452.1 CDS O3M_08975 NC_018650.1 1875097 1875414 D hypothetical protein 1875097..1875414 Escherichia coli O104:H4 str. 2009EL-2050 13693341 YP_006769453.1 CDS O3M_08980 NC_018650.1 1875744 1877105 R COG0826 Collagenase and related proteases; protease complement(1875744..1877105) Escherichia coli O104:H4 str. 2009EL-2050 13693342 YP_006769454.1 CDS O3M_08985 NC_018650.1 1877208 1877504 R COG3668 Plasmid stabilization system protein; plasmid stabilization system protein complement(1877208..1877504) Escherichia coli O104:H4 str. 2009EL-2050 13693343 YP_006769455.1 CDS O3M_08990 NC_018650.1 1877506 1877802 R COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain; transcriptional regulator complement(1877506..1877802) Escherichia coli O104:H4 str. 2009EL-2050 13693344 YP_006769456.1 CDS O3M_08995 NC_018650.1 1878011 1878343 R COG3422 Uncharacterized conserved protein; hypothetical protein complement(1878011..1878343) Escherichia coli O104:H4 str. 2009EL-2050 13693345 YP_006769457.1 CDS O3M_09000 NC_018650.1 1878534 1879256 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator BaeR complement(1878534..1879256) Escherichia coli O104:H4 str. 2009EL-2050 13693346 YP_006769458.1 CDS O3M_09005 NC_018650.1 1879253 1880656 R COG0642 Signal transduction histidine kinase; signal transduction histidine-protein kinase BaeS complement(1879253..1880656) Escherichia coli O104:H4 str. 2009EL-2050 13693347 YP_006769459.1 CDS O3M_09010 NC_018650.1 1880653 1882068 R COG0477 Permeases of the major facilitator superfamily; transporter complement(1880653..1882068) Escherichia coli O104:H4 str. 2009EL-2050 13693348 YP_006769460.1 CDS O3M_09015 NC_018650.1 1882069 1885146 R COG0841 Cation/multidrug efflux pump; multidrug efflux system subunit MdtC complement(1882069..1885146) Escherichia coli O104:H4 str. 2009EL-2050 13693349 YP_006769461.1 CDS O3M_09020 NC_018650.1 1885147 1888269 R COG0841 Cation/multidrug efflux pump; multidrug efflux system subunit MdtB complement(1885147..1888269) Escherichia coli O104:H4 str. 2009EL-2050 13693350 YP_006769462.1 CDS O3M_09025 NC_018650.1 1888269 1889516 R COG0845 Membrane-fusion protein; multidrug efflux system subunit MdtA complement(1888269..1889516) Escherichia coli O104:H4 str. 2009EL-2050 13693351 YP_006769463.1 CDS O3M_09030 NC_018650.1 1890732 1891391 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; hypothetical protein 1890732..1891391 Escherichia coli O104:H4 str. 2009EL-2050 13693352 YP_006769464.1 CDS O3M_09035 NC_018650.1 1891388 1892149 D hypothetical protein 1891388..1892149 Escherichia coli O104:H4 str. 2009EL-2050 13693353 YP_006769465.1 CDS O3M_09040 NC_018650.1 1892146 1894086 D COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains; hypothetical protein 1892146..1894086 Escherichia coli O104:H4 str. 2009EL-2050 13693354 YP_006769466.1 CDS O3M_09045 NC_018650.1 1894098 1895450 R COG0443 Molecular chaperone; chaperone complement(1894098..1895450) Escherichia coli O104:H4 str. 2009EL-2050 13693355 YP_006769467.1 CDS O3M_09050 NC_018650.1 1895584 1896441 D COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; 3-methyladenine DNA glycosylase 1895584..1896441 Escherichia coli O104:H4 str. 2009EL-2050 13693356 YP_006769468.1 CDS O3M_09055 NC_018650.1 1896480 1899797 R COG2202 FOG: PAS/PAC domain; diguanylate cyclase complement(1896480..1899797) Escherichia coli O104:H4 str. 2009EL-2050 13693357 YP_006769469.1 CDS O3M_09060 NC_018650.1 1900115 1900756 D COG0572 Uridine kinase; uridine/cytidine kinase 1900115..1900756 Escherichia coli O104:H4 str. 2009EL-2050 13693358 YP_006769470.1 CDS dcd NC_018650.1 1900848 1901429 D COG0717 Deoxycytidine deaminase; deoxycytidine triphosphate deaminase 1900848..1901429 Escherichia coli O104:H4 str. 2009EL-2050 13693359 YP_006769471.1 CDS O3M_09070 NC_018650.1 1901451 1903304 D COG2982 Uncharacterized protein involved in outer membrane biogenesis; assembly protein 1901451..1903304 Escherichia coli O104:H4 str. 2009EL-2050 13693360 YP_006769472.1 CDS O3M_09075 NC_018650.1 1903578 1905161 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein complement(1903578..1905161) Escherichia coli O104:H4 str. 2009EL-2050 13693361 YP_006769473.1 CDS O3M_09080 NC_018650.1 1905820 1906959 D COG1596 Periplasmic protein involved in polysaccharide export; polysaccharide export protein Wza 1905820..1906959 Escherichia coli O104:H4 str. 2009EL-2050 13693362 YP_006769474.1 CDS O3M_09085 NC_018650.1 1906965 1907408 D COG0394 Protein-tyrosine-phosphatase; tyrosine phosphatase 1906965..1907408 Escherichia coli O104:H4 str. 2009EL-2050 13693363 YP_006769475.1 CDS O3M_09090 NC_018650.1 1907411 1909573 D COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; tyrosine kinase 1907411..1909573 Escherichia coli O104:H4 str. 2009EL-2050 13693364 YP_006769476.1 CDS O3M_09095 NC_018650.1 1909751 1910590 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1909751..1910590 Escherichia coli O104:H4 str. 2009EL-2050 13693365 YP_006769477.1 CDS O3M_09100 NC_018650.1 1910593 1911081 D COG1045 Serine acetyltransferase; acyl transferase 1910593..1911081 Escherichia coli O104:H4 str. 2009EL-2050 13693366 YP_006769478.1 CDS O3M_09105 NC_018650.1 1911078 1912295 D COG0438 Glycosyltransferase; glycosyl transferase family protein 1911078..1912295 Escherichia coli O104:H4 str. 2009EL-2050 13693367 YP_006769479.1 CDS wcaD NC_018650.1 1912270 1913487 D colanic acid biosynthesis protein 1912270..1913487 Escherichia coli O104:H4 str. 2009EL-2050 13693368 YP_006769480.1 CDS O3M_09115 NC_018650.1 1913498 1914244 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1913498..1914244 Escherichia coli O104:H4 str. 2009EL-2050 13693369 YP_006769481.1 CDS O3M_09120 NC_018650.1 1914260 1914808 D COG0110 Acetyltransferase (isoleucine patch superfamily); acyl transferase 1914260..1914808 Escherichia coli O104:H4 str. 2009EL-2050 13693370 YP_006769482.1 CDS O3M_09125 NC_018650.1 1914835 1915956 D COG1089 GDP-D-mannose dehydratase; GDP-mannose 4,6-dehydratase 1914835..1915956 Escherichia coli O104:H4 str. 2009EL-2050 13693371 YP_006769483.1 CDS O3M_09130 NC_018650.1 1915959 1916924 D COG0451 Nucleoside-diphosphate-sugar epimerases; bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/GDP-4-dehydro-6-L-deoxygalactose reductase 1915959..1916924 Escherichia coli O104:H4 str. 2009EL-2050 13693372 YP_006769484.1 CDS O3M_09135 NC_018650.1 1916927 1917406 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; GDP-mannose mannosyl hydrolase 1916927..1917406 Escherichia coli O104:H4 str. 2009EL-2050 13693373 YP_006769485.1 CDS O3M_09140 NC_018650.1 1917403 1918626 D COG0438 Glycosyltransferase; glycosyl transferase family protein 1917403..1918626 Escherichia coli O104:H4 str. 2009EL-2050 13693374 YP_006769486.1 CDS cpsB NC_018650.1 1918629 1920065 D COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanyltransferase 1918629..1920065 Escherichia coli O104:H4 str. 2009EL-2050 13693375 YP_006769487.1 CDS O3M_09150 NC_018650.1 1920434 1921804 D COG1109 Phosphomannomutase; phosphomannomutase 1920434..1921804 Escherichia coli O104:H4 str. 2009EL-2050 13693376 YP_006769488.1 CDS O3M_09155 NC_018650.1 1921859 1923253 D COG2148 Sugar transferases involved in lipopolysaccharide synthesis; UDP-glucose lipid carrier transferase 1921859..1923253 Escherichia coli O104:H4 str. 2009EL-2050 13693377 YP_006769489.1 CDS O3M_09160 NC_018650.1 1923255 1924733 D COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; colanic acid exporter 1923255..1924733 Escherichia coli O104:H4 str. 2009EL-2050 13693378 YP_006769490.1 CDS O3M_09165 NC_018650.1 1925018 1926298 D COG2327 Uncharacterized conserved protein; colanic acid biosynthesis protein 1925018..1926298 Escherichia coli O104:H4 str. 2009EL-2050 13693379 YP_006769491.1 CDS O3M_09170 NC_018650.1 1926295 1927515 D COG0438 Glycosyltransferase; colanic acid biosynthesis glycosyltransferase WcaL 1926295..1927515 Escherichia coli O104:H4 str. 2009EL-2050 13693380 YP_006769492.1 CDS wcaM NC_018650.1 1927526 1928920 D colanic acid biosynthesis protein 1927526..1928920 Escherichia coli O104:H4 str. 2009EL-2050 13693381 YP_006769493.1 CDS O3M_09180 NC_018650.1 1929078 1930073 D COG0451 Nucleoside-diphosphate-sugar epimerases; UDP-N-acetylglucosamine 4-epimerase 1929078..1930073 Escherichia coli O104:H4 str. 2009EL-2050 13693382 YP_006769494.1 CDS O3M_09185 NC_018650.1 1930316 1931209 D COG1210 UDP-glucose pyrophosphorylase; GalU regulator GalF 1930316..1931209 Escherichia coli O104:H4 str. 2009EL-2050 13693383 YP_006769495.1 CDS O3M_09190 NC_018650.1 1931570 1932190 D COG0110 Acetyltransferase (isoleucine patch superfamily); WckD 1931570..1932190 Escherichia coli O104:H4 str. 2009EL-2050 13693384 YP_006769496.1 CDS O3M_09195 NC_018650.1 1932195 1933235 D COG2089 Sialic acid synthase; NnaB 1932195..1933235 Escherichia coli O104:H4 str. 2009EL-2050 13693385 YP_006769497.1 CDS O3M_09200 NC_018650.1 1933241 1934506 D COG1083 CMP-N-acetylneuraminic acid synthetase; N-acylneuraminate cytidylyltransferase 1933241..1934506 Escherichia coli O104:H4 str. 2009EL-2050 13693386 YP_006769498.1 CDS O3M_09205 NC_018650.1 1934503 1935666 D COG0381 UDP-N-acetylglucosamine 2-epimerase; NnaA 1934503..1935666 Escherichia coli O104:H4 str. 2009EL-2050 13693387 YP_006769499.1 CDS O3M_09210 NC_018650.1 1935751 1936701 D hypothetical protein 1935751..1936701 Escherichia coli O104:H4 str. 2009EL-2050 13693388 YP_006769500.1 CDS O3M_09215 NC_018650.1 1936698 1937810 D hypothetical protein 1936698..1937810 Escherichia coli O104:H4 str. 2009EL-2050 13693389 YP_006769501.1 CDS O3M_09220 NC_018650.1 1937816 1939039 D COG0438 Glycosyltransferase; WbwB 1937816..1939039 Escherichia coli O104:H4 str. 2009EL-2050 13693390 YP_006769502.1 CDS O3M_09225 NC_018650.1 1939039 1940316 D COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Wzx 1939039..1940316 Escherichia coli O104:H4 str. 2009EL-2050 13693391 YP_006769503.1 CDS O3M_09230 NC_018650.1 1940341 1941147 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1940341..1941147 Escherichia coli O104:H4 str. 2009EL-2050 13693392 YP_006769504.1 CDS O3M_09235 NC_018650.1 1941268 1942674 D COG0362 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase 1941268..1942674 Escherichia coli O104:H4 str. 2009EL-2050 13693393 YP_006769505.1 CDS O3M_09240 NC_018650.1 1942922 1944088 D COG1004 Predicted UDP-glucose 6-dehydrogenase; UDP-glucose 6-dehydrogenase 1942922..1944088 Escherichia coli O104:H4 str. 2009EL-2050 13693394 YP_006769506.1 CDS O3M_09245 NC_018650.1 1944235 1945212 D COG3765 Chain length determinant protein; chain length determinant protein WzzB 1944235..1945212 Escherichia coli O104:H4 str. 2009EL-2050 13693395 YP_006769507.1 CDS O3M_09250 NC_018650.1 1945310 1945921 R COG0139 Phosphoribosyl-AMP cyclohydrolase; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase complement(1945310..1945921) Escherichia coli O104:H4 str. 2009EL-2050 13693396 YP_006769508.1 CDS O3M_09255 NC_018650.1 1945915 1946691 R COG0107 Imidazoleglycerol-phosphate synthase; imidazole glycerol phosphate synthase subunit HisF complement(1945915..1946691) Escherichia coli O104:H4 str. 2009EL-2050 13693397 YP_006769509.1 CDS O3M_09260 NC_018650.1 1946673 1947410 R COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase complement(1946673..1947410) Escherichia coli O104:H4 str. 2009EL-2050 13693398 YP_006769510.1 CDS hisH NC_018650.1 1947410 1948000 R COG0118 Glutamine amidotransferase; imidazole glycerol phosphate synthase subunit HisH complement(1947410..1948000) Escherichia coli O104:H4 str. 2009EL-2050 13693399 YP_006769511.1 CDS O3M_09270 NC_018650.1 1948000 1949067 R COG0241 Histidinol phosphatase and related phosphatases; imidazole glycerol-phosphate dehydratase/histidinol phosphatase complement(1948000..1949067) Escherichia coli O104:H4 str. 2009EL-2050 13693400 YP_006769512.1 CDS O3M_09275 NC_018650.1 1949067 1950137 R COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; histidinol-phosphate aminotransferase complement(1949067..1950137) Escherichia coli O104:H4 str. 2009EL-2050 13693401 YP_006769513.1 CDS hisD NC_018650.1 1950134 1951438 R COG0141 Histidinol dehydrogenase; bifunctional histidinal dehydrogenase/ histidinol dehydrogenase complement(1950134..1951438) Escherichia coli O104:H4 str. 2009EL-2050 13693402 YP_006769514.1 CDS hisG NC_018650.1 1951444 1952343 R COG0040 ATP phosphoribosyltransferase; ATP phosphoribosyltransferase complement(1951444..1952343) Escherichia coli O104:H4 str. 2009EL-2050 13693403 YP_006769515.1 CDS O3M_09290 NC_018650.1 1952823 1953074 D COG2161 Antitoxin of toxin-antitoxin stability system; antitoxin YefM 1952823..1953074 Escherichia coli O104:H4 str. 2009EL-2050 13693404 YP_006769516.1 CDS O3M_09295 NC_018650.1 1953071 1953325 D COG4115 Uncharacterized protein conserved in bacteria; Toxin yoeB 1953071..1953325 Escherichia coli O104:H4 str. 2009EL-2050 13693405 YP_006769517.1 CDS O3M_09300 NC_018650.1 1953408 1954232 D COG0451 Nucleoside-diphosphate-sugar epimerases; epimerase, with NAD(P)-binding Rossmann-fold domain 1953408..1954232 Escherichia coli O104:H4 str. 2009EL-2050 13693406 YP_006769518.1 CDS O3M_09305 NC_018650.1 1954278 1955207 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 1954278..1955207 Escherichia coli O104:H4 str. 2009EL-2050 13693407 YP_006769519.1 CDS O3M_09310 NC_018650.1 1955474 1956832 D COG0531 Amino acid transporters; amino acid permease 1955474..1956832 Escherichia coli O104:H4 str. 2009EL-2050 13693408 YP_006769520.1 CDS O3M_09315 NC_018650.1 1957011 1958069 D COG2391 Predicted transporter component; hypothetical protein 1957011..1958069 Escherichia coli O104:H4 str. 2009EL-2050 13693409 YP_006769521.1 CDS O3M_09320 NC_018650.1 1958083 1958310 D COG0425 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 1958083..1958310 Escherichia coli O104:H4 str. 2009EL-2050 13693410 YP_006769522.1 CDS sbcB NC_018650.1 1958353 1959777 R COG2925 Exonuclease I; exonuclease I complement(1958353..1959777) Escherichia coli O104:H4 str. 2009EL-2050 13693411 YP_006769523.1 CDS dacD NC_018650.1 1959989 1961155 D COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 1959989..1961155 Escherichia coli O104:H4 str. 2009EL-2050 13693412 YP_006769524.1 CDS O3M_09335 NC_018650.1 1961274 1961747 D COG3449 DNA gyrase inhibitor; DNA gyrase inhibitor 1961274..1961747 Escherichia coli O104:H4 str. 2009EL-2050 13693413 YP_006769525.1 CDS O3M_09340 NC_018650.1 1961945 1962625 D COG1289 Predicted membrane protein; inner membrane protein YeeA 1961945..1962625 Escherichia coli O104:H4 str. 2009EL-2050 13693414 YP_006769526.1 CDS O3M_09345 NC_018650.1 1962689 1963669 D COG3547 Transposase and inactivated derivatives; IS621 transposase 1962689..1963669 Escherichia coli O104:H4 str. 2009EL-2050 13693415 YP_006769527.1 CDS O3M_09350 NC_018650.1 1963860 1964282 D inner membrane protein YeeA 1963860..1964282 Escherichia coli O104:H4 str. 2009EL-2050 13693416 YP_006769528.1 CDS O3M_09355 NC_018650.1 1964454 1964783 D COG2926 Uncharacterized protein conserved in bacteria; hypothetical protein 1964454..1964783 Escherichia coli O104:H4 str. 2009EL-2050 13693417 YP_006769529.1 CDS O3M_09360 NC_018650.1 1964884 1965108 R COG4917 Ethanolamine utilization protein; hypothetical protein complement(1964884..1965108) Escherichia coli O104:H4 str. 2009EL-2050 13693418 YP_006769530.1 CDS O3M_09365 NC_018650.1 1965555 1965668 R hypothetical protein complement(1965555..1965668) Escherichia coli O104:H4 str. 2009EL-2050 13693419 YP_006769531.1 CDS O3M_09370 NC_018650.1 1965681 1965875 R hypothetical protein complement(1965681..1965875) Escherichia coli O104:H4 str. 2009EL-2050 13693420 YP_006769532.1 CDS O3M_09375 NC_018650.1 1965982 1966245 R hypothetical protein complement(1965982..1966245) Escherichia coli O104:H4 str. 2009EL-2050 13693421 YP_006769533.1 CDS O3M_09380 NC_018650.1 1966334 1966702 R hypothetical protein complement(1966334..1966702) Escherichia coli O104:H4 str. 2009EL-2050 13693422 YP_006769534.1 CDS O3M_09385 NC_018650.1 1966776 1966997 R hypothetical protein complement(1966776..1966997) Escherichia coli O104:H4 str. 2009EL-2050 13693423 YP_006769535.1 CDS O3M_09390 NC_018650.1 1967060 1967536 R COG2003 DNA repair proteins; DNA repair protein complement(1967060..1967536) Escherichia coli O104:H4 str. 2009EL-2050 13693424 YP_006769536.1 CDS O3M_09395 NC_018650.1 1967552 1968031 R antirestriction protein complement(1967552..1968031) Escherichia coli O104:H4 str. 2009EL-2050 13693425 YP_006769537.1 CDS O3M_09400 NC_018650.1 1968113 1968934 R hypothetical protein complement(1968113..1968934) Escherichia coli O104:H4 str. 2009EL-2050 13693426 YP_006769538.1 CDS O3M_09405 NC_018650.1 1969155 1969565 R hypothetical protein complement(1969155..1969565) Escherichia coli O104:H4 str. 2009EL-2050 13693427 YP_006769539.1 CDS O3M_09410 NC_018650.1 1969581 1970264 R hypothetical protein complement(1969581..1970264) Escherichia coli O104:H4 str. 2009EL-2050 13693428 YP_006769540.1 CDS O3M_09415 NC_018650.1 1970400 1971470 R COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein complement(1970400..1971470) Escherichia coli O104:H4 str. 2009EL-2050 13693429 YP_006769541.1 CDS O3M_09420 NC_018650.1 1971467 1972372 R hypothetical protein complement(1971467..1972372) Escherichia coli O104:H4 str. 2009EL-2050 13693430 YP_006769542.1 CDS O3M_09425 NC_018650.1 1972369 1974765 R COG0699 Predicted GTPases (dynamin-related); hypothetical protein complement(1972369..1974765) Escherichia coli O104:H4 str. 2009EL-2050 13693431 YP_006769543.1 CDS O3M_09440 NC_018650.1 1975938 1977089 R hypothetical protein complement(1975938..1977089) Escherichia coli O104:H4 str. 2009EL-2050 13693432 YP_006769544.1 CDS O3M_09445 NC_018650.1 1978293 1978568 R COG4584 Transposase and inactivated derivatives; transposase subunit complement(1978293..1978568) Escherichia coli O104:H4 str. 2009EL-2050 13693433 YP_006769545.1 CDS O3M_09450 NC_018650.1 1978474 1978770 R hypothetical protein complement(1978474..1978770) Escherichia coli O104:H4 str. 2009EL-2050 13693434 YP_006769546.1 CDS O3M_09455 NC_018650.1 1978657 1979040 D COG2963 Transposase and inactivated derivatives; hypothetical protein 1978657..1979040 Escherichia coli O104:H4 str. 2009EL-2050 13693435 YP_006769547.1 CDS O3M_09460 NC_018650.1 1979037 1979384 D COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF 2, IS66 family protein 1979037..1979384 Escherichia coli O104:H4 str. 2009EL-2050 13693436 YP_006769548.1 CDS O3M_09465 NC_018650.1 1979434 1980969 D COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF 1, IS66 family protein 1979434..1980969 Escherichia coli O104:H4 str. 2009EL-2050 13693437 YP_006769549.1 CDS O3M_09470 NC_018650.1 1981928 1982536 R hypothetical protein complement(1981928..1982536) Escherichia coli O104:H4 str. 2009EL-2050 13693438 YP_006769550.1 CDS O3M_09475 NC_018650.1 1982624 1982830 R COG3311 Predicted transcriptional regulator; InterPro motifs Prophage CP4-57 regulatory protein (AlpA) complement(1982624..1982830) Escherichia coli O104:H4 str. 2009EL-2050 13693439 YP_006769551.1 CDS O3M_09480 NC_018650.1 1982937 1983239 D hypothetical protein 1982937..1983239 Escherichia coli O104:H4 str. 2009EL-2050 13693440 YP_006769552.1 CDS O3M_09485 NC_018650.1 1983957 1984157 R hypothetical protein complement(1983957..1984157) Escherichia coli O104:H4 str. 2009EL-2050 13693441 YP_006769553.1 CDS O3M_09490 NC_018650.1 1984357 1984926 D hypothetical protein 1984357..1984926 Escherichia coli O104:H4 str. 2009EL-2050 13693442 YP_006769554.1 CDS O3M_09495 NC_018650.1 1985180 1985587 D COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 1985180..1985587 Escherichia coli O104:H4 str. 2009EL-2050 13693443 YP_006769555.1 CDS O3M_09500 NC_018650.1 1985575 1985985 D hypothetical protein 1985575..1985985 Escherichia coli O104:H4 str. 2009EL-2050 13693444 YP_006769556.1 CDS O3M_09505 NC_018650.1 1986408 1986659 R hypothetical protein complement(1986408..1986659) Escherichia coli O104:H4 str. 2009EL-2050 13693445 YP_006769557.1 CDS O3M_09510 NC_018650.1 1986791 1987648 D COG3464 Transposase and inactivated derivatives; transposase, ISL3 family protein 1986791..1987648 Escherichia coli O104:H4 str. 2009EL-2050 13693446 YP_006769558.1 CDS O3M_09515 NC_018650.1 1987727 1987888 D COG3464 Transposase and inactivated derivatives; transposase (part) 1987727..1987888 Escherichia coli O104:H4 str. 2009EL-2050 13693447 YP_006769559.1 CDS O3M_09520 NC_018650.1 1987989 1988156 D COG0405 Gamma-glutamyltransferase; hypothetical protein 1987989..1988156 Escherichia coli O104:H4 str. 2009EL-2050 13693448 YP_006769560.1 CDS O3M_09525 NC_018650.1 1988147 1988260 D hypothetical protein 1988147..1988260 Escherichia coli O104:H4 str. 2009EL-2050 13693449 YP_006769561.1 CDS O3M_09530 NC_018650.1 1988300 1989334 R COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold; phosphotriesterase-related protein complement(1988300..1989334) Escherichia coli O104:H4 str. 2009EL-2050 13693450 YP_006769562.1 CDS O3M_09545 NC_018650.1 1990359 1991117 R COG5426 Uncharacterized membrane protein; hypothetical protein complement(1990359..1991117) Escherichia coli O104:H4 str. 2009EL-2050 13693451 YP_006769563.1 CDS O3M_09550 NC_018650.1 1991131 1992345 R COG1349 Transcriptional regulators of sugar metabolism; carbohydrate kinase complement(1991131..1992345) Escherichia coli O104:H4 str. 2009EL-2050 13693452 YP_006769564.1 CDS O3M_09555 NC_018650.1 1992541 1992657 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(1992541..1992657) Escherichia coli O104:H4 str. 2009EL-2050 13693453 YP_006769565.1 CDS O3M_09560 NC_018650.1 1992597 1993088 R hypothetical protein complement(1992597..1993088) Escherichia coli O104:H4 str. 2009EL-2050 13693454 YP_006769566.1 CDS O3M_09565 NC_018650.1 1993779 1993943 D hypothetical protein 1993779..1993943 Escherichia coli O104:H4 str. 2009EL-2050 13693455 YP_006769567.1 CDS cobU NC_018650.1 1994408 1994953 D COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1994408..1994953 Escherichia coli O104:H4 str. 2009EL-2050 13693456 YP_006769568.1 CDS cobS NC_018650.1 1994950 1995693 D COG0368 Cobalamin-5-phosphate synthase; cobalamin synthase 1994950..1995693 Escherichia coli O104:H4 str. 2009EL-2050 13693457 YP_006769569.1 CDS cobT NC_018650.1 1995705 1996784 D COG2038 NaMN:DMB phosphoribosyltransferase; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1995705..1996784 Escherichia coli O104:H4 str. 2009EL-2050 13693458 YP_006769570.1 CDS O3M_09585 NC_018650.1 1996849 1997781 D COG1376 Uncharacterized protein conserved in bacteria; L,D-transpeptidase 1996849..1997781 Escherichia coli O104:H4 str. 2009EL-2050 13693459 YP_006769571.1 CDS O3M_09590 NC_018650.1 1998239 1999156 D COG0583 Transcriptional regulator; nitrogen assimilation transcriptional regulator 1998239..1999156 Escherichia coli O104:H4 str. 2009EL-2050 13693461 YP_006769572.1 CDS cbl NC_018650.1 1999258 2000208 D COG0583 Transcriptional regulator; transcriptional regulator Cbl 1999258..2000208 Escherichia coli O104:H4 str. 2009EL-2050 13693462 YP_006769573.1 CDS O3M_09600 NC_018650.1 2000329 2001969 D COG0534 Na+-driven multidrug efflux pump; MATE family multidrug exporter 2000329..2001969 Escherichia coli O104:H4 str. 2009EL-2050 13693464 YP_006769574.1 CDS O3M_09605 NC_018650.1 2002597 2003313 R COG0217 Uncharacterized conserved protein; hypothetical protein complement(2002597..2003313) Escherichia coli O104:H4 str. 2009EL-2050 13693466 YP_006769575.1 CDS O3M_09610 NC_018650.1 2003656 2005110 R COG0775 Nucleoside phosphorylase; AMP nucleosidase complement(2003656..2005110) Escherichia coli O104:H4 str. 2009EL-2050 13693467 YP_006769576.1 CDS O3M_09615 NC_018650.1 2005212 2006528 R COG0477 Permeases of the major facilitator superfamily; shikimate transporter complement(2005212..2006528) Escherichia coli O104:H4 str. 2009EL-2050 13693468 YP_006769577.1 CDS O3M_09620 NC_018650.1 2006843 2007895 D COG0859 ADP-heptose:LPS heptosyltransferase; hypothetical protein 2006843..2007895 Escherichia coli O104:H4 str. 2009EL-2050 13693469 YP_006769578.1 CDS O3M_09635 NC_018650.1 2010017 2010157 R hypothetical protein complement(2010017..2010157) Escherichia coli O104:H4 str. 2009EL-2050 13693470 YP_006769579.1 CDS O3M_09640 NC_018650.1 2010114 2010536 R hypothetical protein complement(2010114..2010536) Escherichia coli O104:H4 str. 2009EL-2050 13693471 YP_006769580.1 CDS O3M_09645 NC_018650.1 2011514 2013535 R COG1629 Outer membrane receptor proteins, mostly Fe transport; Yersiniabactin/pesticin outer membrane receptor (IRPC) complement(2011514..2013535) Escherichia coli O104:H4 str. 2009EL-2050 13693472 YP_006769581.1 CDS O3M_09650 NC_018650.1 2013666 2015243 R COG1021 Peptide arylation enzymes; salicyl-AMP ligase YbtE complement(2013666..2015243) Escherichia coli O104:H4 str. 2009EL-2050 13693473 YP_006769582.1 CDS O3M_09655 NC_018650.1 2015247 2016050 R COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis; siderophore biosynthetic protein complement(2015247..2016050) Escherichia coli O104:H4 str. 2009EL-2050 13693474 YP_006769583.1 CDS O3M_09660 NC_018650.1 2016047 2017147 R COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis; Thiazolinyl-S-HMWP1 reductase YbtU complement(2016047..2017147) Escherichia coli O104:H4 str. 2009EL-2050 13693475 YP_006769584.1 CDS O3M_09665 NC_018650.1 2017144 2026635 R COG3321 Polyketide synthase modules and related proteins; High-molecular-weight nonribosomal peptide/polyketide synthetase 1 (HMWP1) complement(2017144..2026635) Escherichia coli O104:H4 str. 2009EL-2050 13693476 YP_006769585.1 CDS O3M_09670 NC_018650.1 2026723 2032830 R COG1020 Non-ribosomal peptide synthetase modules and related proteins; High-molecular-weight nonribosomal peptide/polyketide synthetase 2 (HMWP2) complement(2026723..2032830) Escherichia coli O104:H4 str. 2009EL-2050 13693477 YP_006769586.1 CDS O3M_09675 NC_018650.1 2033021 2033980 R COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator complement(2033021..2033980) Escherichia coli O104:H4 str. 2009EL-2050 13693478 YP_006769587.1 CDS O3M_09680 NC_018650.1 2034147 2035949 D COG1132 ABC-type multidrug transport system, ATPase and permease components; yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtP 2034147..2035949 Escherichia coli O104:H4 str. 2009EL-2050 13693479 YP_006769588.1 CDS O3M_09685 NC_018650.1 2035936 2037738 D COG1132 ABC-type multidrug transport system, ATPase and permease components; yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtQ 2035936..2037738 Escherichia coli O104:H4 str. 2009EL-2050 13693480 YP_006769589.1 CDS O3M_09690 NC_018650.1 2037731 2039011 D COG0477 Permeases of the major facilitator superfamily; yersiniabactin-iron transporter permease YbtX 2037731..2039011 Escherichia coli O104:H4 str. 2009EL-2050 13693481 YP_006769590.1 CDS O3M_09695 NC_018650.1 2039039 2040343 D COG0147 Anthranilate/para-aminobenzoate synthases component I; salicylate synthase Irp9 2039039..2040343 Escherichia coli O104:H4 str. 2009EL-2050 13693482 YP_006769591.1 CDS O3M_09700 NC_018650.1 2040537 2041799 R COG0582 Integrase; integrase complement(2040537..2041799) Escherichia coli O104:H4 str. 2009EL-2050 13693483 YP_006769592.1 CDS O3M_09705 NC_018650.1 2042137 2042934 R COG3228 Uncharacterized protein conserved in bacteria; DgsA anti-repressor MtfA complement(2042137..2042934) Escherichia coli O104:H4 str. 2009EL-2050 13693485 YP_006769593.1 CDS O3M_09710 NC_018650.1 2043787 2044437 R COG3443 Predicted periplasmic or secreted protein; zinc/cadmium-binding protein complement(2043787..2044437) Escherichia coli O104:H4 str. 2009EL-2050 13693487 YP_006769594.1 CDS O3M_09715 NC_018650.1 2044694 2045329 R COG2717 Predicted membrane protein; sulfite oxidase subunit YedZ complement(2044694..2045329) Escherichia coli O104:H4 str. 2009EL-2050 13693488 YP_006769595.1 CDS O3M_09720 NC_018650.1 2045330 2046334 R COG2041 Sulfite oxidase and related enzymes; TMAO/DMSO reductase complement(2045330..2046334) Escherichia coli O104:H4 str. 2009EL-2050 13693489 YP_006769596.1 CDS O3M_09725 NC_018650.1 2046443 2046856 R COG2351 Transthyretin-like protein; hydroxyisourate hydrolase complement(2046443..2046856) Escherichia coli O104:H4 str. 2009EL-2050 13693490 YP_006769597.1 CDS O3M_09730 NC_018650.1 2046989 2047660 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulatory protein YedW 2046989..2047660 Escherichia coli O104:H4 str. 2009EL-2050 13693491 YP_006769598.1 CDS O3M_09735 NC_018650.1 2047660 2049018 D COG0642 Signal transduction histidine kinase; sensory kinase in two-component regulatory system with YedW 2047660..2049018 Escherichia coli O104:H4 str. 2009EL-2050 13693492 YP_006769599.1 CDS O3M_09740 NC_018650.1 2049116 2049967 R COG0693 Putative intracellular protease/amidase; chaperone protein HchA complement(2049116..2049967) Escherichia coli O104:H4 str. 2009EL-2050 13693493 YP_006769600.1 CDS O3M_09745 NC_018650.1 2050053 2050328 D COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA 2050053..2050328 Escherichia coli O104:H4 str. 2009EL-2050 13693494 YP_006769601.1 CDS O3M_09750 NC_018650.1 2050247 2050750 D COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 2050247..2050750 Escherichia coli O104:H4 str. 2009EL-2050 13693495 YP_006769602.1 CDS O3M_09755 NC_018650.1 2051256 2051969 R COG2801 Transposase and inactivated derivatives; hypothetical protein complement(2051256..2051969) Escherichia coli O104:H4 str. 2009EL-2050 13693496 YP_006769603.1 CDS O3M_09760 NC_018650.1 2052214 2053365 D COG2826 Transposase and inactivated derivatives, IS30 family; IS30 transposase: KpLE2 phage-like element 2052214..2053365 Escherichia coli O104:H4 str. 2009EL-2050 13693497 YP_006769604.1 CDS O3M_09765 NC_018650.1 2053285 2053635 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(2053285..2053635) Escherichia coli O104:H4 str. 2009EL-2050 13693498 YP_006769605.1 CDS O3M_09780 NC_018650.1 2055312 2055677 D COG0477 Permeases of the major facilitator superfamily; inner membrane protein 2055312..2055677 Escherichia coli O104:H4 str. 2009EL-2050 13693499 YP_006769606.1 CDS O3M_09785 NC_018650.1 2055717 2056412 D COG1418 Predicted HD superfamily hydrolase; hydrolase 2055717..2056412 Escherichia coli O104:H4 str. 2009EL-2050 13693500 YP_006769607.1 CDS O3M_09790 NC_018650.1 2056479 2057897 D COG0270 Site-specific DNA methylase; DNA cytosine methylase 2056479..2057897 Escherichia coli O104:H4 str. 2009EL-2050 13693501 YP_006769608.1 CDS O3M_09795 NC_018650.1 2057878 2058348 D COG3727 DNA G:T-mismatch repair endonuclease; very short patch repair protein 2057878..2058348 Escherichia coli O104:H4 str. 2009EL-2050 13693502 YP_006769609.1 CDS O3M_09800 NC_018650.1 2058337 2059257 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; DMT superfamily transporter inner membrane protein complement(2058337..2059257) Escherichia coli O104:H4 str. 2009EL-2050 13693503 YP_006769610.1 CDS O3M_09805 NC_018650.1 2059430 2060347 D COG2354 Uncharacterized protein conserved in bacteria; hypothetical protein 2059430..2060347 Escherichia coli O104:H4 str. 2009EL-2050 13693504 YP_006769611.1 CDS O3M_09810 NC_018650.1 2060426 2060608 D COG5475 Uncharacterized small protein; hypothetical protein 2060426..2060608 Escherichia coli O104:H4 str. 2009EL-2050 13693505 YP_006769612.1 CDS O3M_09815 NC_018650.1 2060779 2061714 D diguanylate cyclase 2060779..2061714 Escherichia coli O104:H4 str. 2009EL-2050 13693506 YP_006769613.1 CDS O3M_09820 NC_018650.1 2061718 2062473 D COG2199 FOG: GGDEF domain; diguanylate cyclase 2061718..2062473 Escherichia coli O104:H4 str. 2009EL-2050 13693507 YP_006769614.1 CDS O3M_09825 NC_018650.1 2062470 2063285 R COG3769 Predicted hydrolase (HAD superfamily); mannosyl-3-phosphoglycerate phosphatase complement(2062470..2063285) Escherichia coli O104:H4 str. 2009EL-2050 13693508 YP_006769615.1 CDS O3M_09830 NC_018650.1 2063584 2063811 R hypothetical protein complement(2063584..2063811) Escherichia coli O104:H4 str. 2009EL-2050 13693509 YP_006769616.1 CDS O3M_09835 NC_018650.1 2063974 2064162 D hypothetical protein 2063974..2064162 Escherichia coli O104:H4 str. 2009EL-2050 13693510 YP_006769617.1 CDS rcsA NC_018650.1 2064206 2064829 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; colanic acid capsular biosynthesis activation protein A complement(2064206..2064829) Escherichia coli O104:H4 str. 2009EL-2050 13693511 YP_006769618.1 CDS fliR NC_018650.1 2065119 2065904 R COG1684 Flagellar biosynthesis pathway, component FliR; flagellar biosynthesis protein FliR complement(2065119..2065904) Escherichia coli O104:H4 str. 2009EL-2050 13693512 YP_006769619.1 CDS fliQ NC_018650.1 2065913 2066182 R COG1987 Flagellar biosynthesis pathway, component FliQ; flagellar biosynthesis protein FliQ complement(2065913..2066182) Escherichia coli O104:H4 str. 2009EL-2050 13693513 YP_006769620.1 CDS fliP NC_018650.1 2066192 2066929 R COG1338 Flagellar biosynthesis pathway, component FliP; flagellar biosynthesis protein FliP complement(2066192..2066929) Escherichia coli O104:H4 str. 2009EL-2050 13693514 YP_006769621.1 CDS O3M_09860 NC_018650.1 2066929 2067294 R COG3190 Flagellar biogenesis protein; flagellar biosynthesis protein FliO complement(2066929..2067294) Escherichia coli O104:H4 str. 2009EL-2050 13693515 YP_006769622.1 CDS fliN NC_018650.1 2067297 2067710 R COG1886 Flagellar motor switch/type III secretory pathway protein; flagellar motor switch protein FliN complement(2067297..2067710) Escherichia coli O104:H4 str. 2009EL-2050 13693516 YP_006769623.1 CDS fliM NC_018650.1 2067707 2068711 R COG1868 Flagellar motor switch protein; flagellar motor switch protein FliM complement(2067707..2068711) Escherichia coli O104:H4 str. 2009EL-2050 13693517 YP_006769624.1 CDS fliL NC_018650.1 2068716 2069180 R COG1580 Flagellar basal body-associated protein; flagellar basal body-associated protein FliL complement(2068716..2069180) Escherichia coli O104:H4 str. 2009EL-2050 13693518 YP_006769625.1 CDS O3M_09880 NC_018650.1 2069285 2070412 R COG3144 Flagellar hook-length control protein; flagellar hook-length control protein complement(2069285..2070412) Escherichia coli O104:H4 str. 2009EL-2050 13693519 YP_006769626.1 CDS fliJ NC_018650.1 2070409 2070852 R COG2882 Flagellar biosynthesis chaperone; flagellar biosynthesis chaperone complement(2070409..2070852) Escherichia coli O104:H4 str. 2009EL-2050 13693520 YP_006769627.1 CDS fliI NC_018650.1 2070871 2072244 R COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; flagellum-specific ATP synthase complement(2070871..2072244) Escherichia coli O104:H4 str. 2009EL-2050 13693521 YP_006769628.1 CDS fliH NC_018650.1 2072244 2072930 R COG1317 Flagellar biosynthesis/type III secretory pathway protein; flagellar assembly protein H complement(2072244..2072930) Escherichia coli O104:H4 str. 2009EL-2050 13693522 YP_006769629.1 CDS fliG NC_018650.1 2072923 2073918 R COG1536 Flagellar motor switch protein; flagellar motor switch protein G complement(2072923..2073918) Escherichia coli O104:H4 str. 2009EL-2050 13693523 YP_006769630.1 CDS fliF NC_018650.1 2073911 2075569 R COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; flagellar MS-ring protein complement(2073911..2075569) Escherichia coli O104:H4 str. 2009EL-2050 13693524 YP_006769631.1 CDS fliE NC_018650.1 2075784 2076098 D COG1677 Flagellar hook-basal body protein; flagellar hook-basal body protein FliE 2075784..2076098 Escherichia coli O104:H4 str. 2009EL-2050 13693525 YP_006769632.1 CDS emrE NC_018650.1 2076442 2076774 D COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein 2076442..2076774 Escherichia coli O104:H4 str. 2009EL-2050 13693526 YP_006769633.1 CDS O3M_09920 NC_018650.1 2076943 2077494 D COG1881 Phospholipid-binding protein; kinase inhibitor 2076943..2077494 Escherichia coli O104:H4 str. 2009EL-2050 13693527 YP_006769634.1 CDS O3M_09925 NC_018650.1 2077504 2078301 D DLP12 prophage; COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 2077504..2078301 Escherichia coli O104:H4 str. 2009EL-2050 13693528 YP_006769635.1 CDS O3M_09930 NC_018650.1 2078458 2078982 R COG1943 Transposase and inactivated derivatives; IS609 family protein; transposase ORF A, IS609 family protein complement(2078458..2078982) Escherichia coli O104:H4 str. 2009EL-2050 13693529 YP_006769636.1 CDS O3M_09935 NC_018650.1 2079216 2079713 R COG2135 Uncharacterized conserved protein; hypothetical protein complement(2079216..2079713) Escherichia coli O104:H4 str. 2009EL-2050 13693530 YP_006769637.1 CDS O3M_09940 NC_018650.1 2079822 2080055 R COG0425 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein complement(2079822..2080055) Escherichia coli O104:H4 str. 2009EL-2050 13693531 YP_006769638.1 CDS O3M_09945 NC_018650.1 2080052 2081257 R COG2391 Predicted transporter component; inner membrane protein complement(2080052..2081257) Escherichia coli O104:H4 str. 2009EL-2050 13693532 YP_006769639.1 CDS O3M_09950 NC_018650.1 2081444 2081857 D lipoprotein 2081444..2081857 Escherichia coli O104:H4 str. 2009EL-2050 13693533 YP_006769640.1 CDS O3M_09955 NC_018650.1 2081891 2083378 R COG0366 Glycosidases; alpha-amylase complement(2081891..2083378) Escherichia coli O104:H4 str. 2009EL-2050 13693534 YP_006769641.1 CDS O3M_09960 NC_018650.1 2083456 2083821 R COG1012 NAD-dependent aldehyde dehydrogenases; flagellar biosynthesis protein FliT complement(2083456..2083821) Escherichia coli O104:H4 str. 2009EL-2050 13693535 YP_006769642.1 CDS fliS NC_018650.1 2083821 2084231 R COG1516 Flagellin-specific chaperone FliS; flagellar protein FliS complement(2083821..2084231) Escherichia coli O104:H4 str. 2009EL-2050 13693536 YP_006769643.1 CDS fliD NC_018650.1 2084247 2085662 R COG1345 Flagellar capping protein; flagellar capping protein complement(2084247..2085662) Escherichia coli O104:H4 str. 2009EL-2050 13693537 YP_006769644.1 CDS O3M_09975 NC_018650.1 2085910 2086959 D COG1344 Flagellin and related hook-associated proteins; Flagellin 2085910..2086959 Escherichia coli O104:H4 str. 2009EL-2050 13693538 YP_006769645.1 CDS fliA NC_018650.1 2087123 2087842 D COG1191 DNA-directed RNA polymerase specialized sigma subunit; flagellar biosynthesis sigma factor 2087123..2087842 Escherichia coli O104:H4 str. 2009EL-2050 13693539 YP_006769646.1 CDS O3M_09985 NC_018650.1 2087888 2088439 D flagella biosynthesis protein FliZ 2087888..2088439 Escherichia coli O104:H4 str. 2009EL-2050 13693540 YP_006769647.1 CDS O3M_09990 NC_018650.1 2088527 2089327 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; cystine transporter subunit 2088527..2089327 Escherichia coli O104:H4 str. 2009EL-2050 13693541 YP_006769648.1 CDS O3M_09995 NC_018650.1 2089432 2090418 D COG2515 1-aminocyclopropane-1-carboxylate deaminase; D-cysteine desulfhydrase 2089432..2090418 Escherichia coli O104:H4 str. 2009EL-2050 13693542 YP_006769649.1 CDS O3M_10000 NC_018650.1 2090433 2091101 D COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 2090433..2091101 Escherichia coli O104:H4 str. 2009EL-2050 13693543 YP_006769650.1 CDS O3M_10005 NC_018650.1 2091098 2091850 D COG1126 ABC-type polar amino acid transport system, ATPase component; amino-acid ABC transporter ATP-binding protein YecC 2091098..2091850 Escherichia coli O104:H4 str. 2009EL-2050 13693544 YP_006769651.1 CDS O3M_10010 NC_018650.1 2092080 2092802 D COG2771 DNA-binding HTH domain-containing proteins; DNA-binding transcriptional activator SdiA 2092080..2092802 Escherichia coli O104:H4 str. 2009EL-2050 13693545 YP_006769652.1 CDS O3M_10015 NC_018650.1 2092870 2093094 R hypothetical protein complement(2092870..2093094) Escherichia coli O104:H4 str. 2009EL-2050 13693546 YP_006769653.1 CDS O3M_10020 NC_018650.1 2093081 2093257 R hypothetical protein complement(2093081..2093257) Escherichia coli O104:H4 str. 2009EL-2050 13693547 YP_006769654.1 CDS O3M_10025 NC_018650.1 2093553 2094209 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator 2093553..2094209 Escherichia coli O104:H4 str. 2009EL-2050 13693548 YP_006769655.1 CDS uvrC NC_018650.1 2094206 2096038 D COG0322 Nuclease subunit of the excinuclease complex; excinuclease ABC subunit C 2094206..2096038 Escherichia coli O104:H4 str. 2009EL-2050 13693549 YP_006769656.1 CDS O3M_10035 NC_018650.1 2096095 2096643 D COG0558 Phosphatidylglycerophosphate synthase; phosphatidylglycerophosphate synthetase 2096095..2096643 Escherichia coli O104:H4 str. 2009EL-2050 13693550 YP_006769657.1 CDS O3M_10040 NC_018650.1 2097293 2097958 D COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; hypothetical protein 2097293..2097958 Escherichia coli O104:H4 str. 2009EL-2050 13693554 YP_006769658.1 CDS O3M_10045 NC_018650.1 2098020 2099231 R COG0814 Amino acid permeases; tyrosine transporter TyrP complement(2098020..2099231) Escherichia coli O104:H4 str. 2009EL-2050 13693555 YP_006769659.1 CDS O3M_10050 NC_018650.1 2099421 2099660 D hypothetical protein 2099421..2099660 Escherichia coli O104:H4 str. 2009EL-2050 13693556 YP_006769660.1 CDS O3M_10055 NC_018650.1 2099698 2100195 R COG1528 Ferritin-like protein; ferritin complement(2099698..2100195) Escherichia coli O104:H4 str. 2009EL-2050 13693557 YP_006769661.1 CDS O3M_10060 NC_018650.1 2100367 2100690 R hypothetical protein complement(2100367..2100690) Escherichia coli O104:H4 str. 2009EL-2050 13693558 YP_006769662.1 CDS O3M_10065 NC_018650.1 2101154 2101405 D hypothetical protein 2101154..2101405 Escherichia coli O104:H4 str. 2009EL-2050 13693559 YP_006769663.1 CDS O3M_10070 NC_018650.1 2101484 2101987 R COG1528 Ferritin-like protein; ferritin-like protein complement(2101484..2101987) Escherichia coli O104:H4 str. 2009EL-2050 13693560 YP_006769664.1 CDS O3M_10075 NC_018650.1 2102784 2103773 D COG1879 ABC-type sugar transport system, periplasmic component; L-arabinose ABC transporter substrate-binding protein 2102784..2103773 Escherichia coli O104:H4 str. 2009EL-2050 13693561 YP_006769665.1 CDS araG NC_018650.1 2103843 2105357 D COG1129 ABC-type sugar transport system, ATPase component; L-arabinose transporter ATP-binding protein 2103843..2105357 Escherichia coli O104:H4 str. 2009EL-2050 13693562 YP_006769666.1 CDS araH NC_018650.1 2105372 2106358 D COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; L-arabinose transporter permease 2105372..2106358 Escherichia coli O104:H4 str. 2009EL-2050 13693563 YP_006769667.1 CDS O3M_10090 NC_018650.1 2106525 2107325 D COG1877 Trehalose-6-phosphatase; trehalose-6-phosphate phosphatase 2106525..2107325 Escherichia coli O104:H4 str. 2009EL-2050 13693564 YP_006769668.1 CDS O3M_10095 NC_018650.1 2107300 2108724 D COG0380 Trehalose-6-phosphate synthase; trehalose-6-phosphate synthase 2107300..2108724 Escherichia coli O104:H4 str. 2009EL-2050 13693565 YP_006769669.1 CDS O3M_10100 NC_018650.1 2108731 2109159 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspC complement(2108731..2109159) Escherichia coli O104:H4 str. 2009EL-2050 13693566 YP_006769670.1 CDS O3M_10105 NC_018650.1 2109938 2110288 D transcriptional activator FlhD 2109938..2110288 Escherichia coli O104:H4 str. 2009EL-2050 13693567 YP_006769671.1 CDS O3M_10110 NC_018650.1 2110291 2110869 D transcriptional activator FlhC 2110291..2110869 Escherichia coli O104:H4 str. 2009EL-2050 13693568 YP_006769672.1 CDS O3M_10115 NC_018650.1 2110996 2111883 D COG1291 Flagellar motor component; flagellar motor protein MotA 2110996..2111883 Escherichia coli O104:H4 str. 2009EL-2050 13693569 YP_006769673.1 CDS motB NC_018650.1 2111880 2112806 D COG1360 Flagellar motor protein; flagellar motor protein MotB 2111880..2112806 Escherichia coli O104:H4 str. 2009EL-2050 13693570 YP_006769674.1 CDS O3M_10125 NC_018650.1 2112811 2114775 D COG0643 Chemotaxis protein histidine kinase and related kinases; chemotaxis protein CheA 2112811..2114775 Escherichia coli O104:H4 str. 2009EL-2050 13693571 YP_006769675.1 CDS O3M_10130 NC_018650.1 2114796 2115299 D COG0835 Chemotaxis signal transduction protein; purine-binding chemotaxis protein 2114796..2115299 Escherichia coli O104:H4 str. 2009EL-2050 13693572 YP_006769676.1 CDS O3M_10135 NC_018650.1 2115444 2117105 D COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein II 2115444..2117105 Escherichia coli O104:H4 str. 2009EL-2050 13693573 YP_006769677.1 CDS O3M_10140 NC_018650.1 2117151 2118752 D COG0840 Methyl-accepting chemotaxis protein; methyl-accepting protein IV 2117151..2118752 Escherichia coli O104:H4 str. 2009EL-2050 13693574 YP_006769678.1 CDS O3M_10145 NC_018650.1 2118771 2119631 D COG1352 Methylase of chemotaxis methyl-accepting proteins; chemotaxis methyltransferase CheR 2118771..2119631 Escherichia coli O104:H4 str. 2009EL-2050 13693575 YP_006769679.1 CDS O3M_10150 NC_018650.1 2119634 2120683 D COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; chemotaxis-specific methylesterase 2119634..2120683 Escherichia coli O104:H4 str. 2009EL-2050 13693576 YP_006769680.1 CDS O3M_10155 NC_018650.1 2120698 2121087 D COG0784 FOG: CheY-like receiver; chemotaxis regulatory protein CheY 2120698..2121087 Escherichia coli O104:H4 str. 2009EL-2050 13693577 YP_006769681.1 CDS O3M_10160 NC_018650.1 2121098 2121742 D COG3143 Chemotaxis protein; chemotaxis regulator CheZ 2121098..2121742 Escherichia coli O104:H4 str. 2009EL-2050 13693578 YP_006769682.1 CDS flhB NC_018650.1 2121944 2123092 D COG1377 Flagellar biosynthesis pathway, component FlhB; flagellar biosynthesis protein FlhB 2121944..2123092 Escherichia coli O104:H4 str. 2009EL-2050 13693579 YP_006769683.1 CDS flhA NC_018650.1 2123085 2125163 D COG1298 Flagellar biosynthesis pathway, component FlhA; flagellar biosynthesis protein FlhA 2123085..2125163 Escherichia coli O104:H4 str. 2009EL-2050 13693580 YP_006769684.1 CDS O3M_10175 NC_018650.1 2125163 2125555 D flagellar protein FlhE 2125163..2125555 Escherichia coli O104:H4 str. 2009EL-2050 13693581 YP_006769685.1 CDS O3M_10180 NC_018650.1 2125675 2126163 R COG3755 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2125675..2126163) Escherichia coli O104:H4 str. 2009EL-2050 13693582 YP_006769686.1 CDS argS NC_018650.1 2126340 2128073 R COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase complement(2126340..2128073) Escherichia coli O104:H4 str. 2009EL-2050 13693583 YP_006769687.1 CDS O3M_10190 NC_018650.1 2128289 2128855 D COG3102 Uncharacterized protein conserved in bacteria; hypothetical protein 2128289..2128855 Escherichia coli O104:H4 str. 2009EL-2050 13693584 YP_006769688.1 CDS O3M_10195 NC_018650.1 2128869 2129615 D COG3142 Uncharacterized protein involved in copper resistance; copper homeostasis protein CutC 2128869..2129615 Escherichia coli O104:H4 str. 2009EL-2050 13693585 YP_006769689.1 CDS O3M_10200 NC_018650.1 2130003 2131103 D COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; TMAO reductase III (TorYZ), cytochrome c-type subunit TorY 2130003..2131103 Escherichia coli O104:H4 str. 2009EL-2050 13693586 YP_006769690.1 CDS O3M_10205 NC_018650.1 2131128 2133557 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; trimethylamine N-oxide reductase system III, catalytic subunit 2131128..2133557 Escherichia coli O104:H4 str. 2009EL-2050 13693587 YP_006769691.1 CDS O3M_10210 NC_018650.1 2133827 2134807 D COG3547 Transposase and inactivated derivatives; IS621 transposase 2133827..2134807 Escherichia coli O104:H4 str. 2009EL-2050 13693588 YP_006769692.1 CDS O3M_10215 NC_018650.1 2135001 2135972 R COG0500 SAM-dependent methyltransferases; tRNA mo(5)U34 methyltransferase complement(2135001..2135972) Escherichia coli O104:H4 str. 2009EL-2050 13693589 YP_006769693.1 CDS O3M_10220 NC_018650.1 2135969 2136712 R COG0500 SAM-dependent methyltransferases; tRNA cmo(5)U34 methyltransferase complement(2135969..2136712) Escherichia coli O104:H4 str. 2009EL-2050 13693590 YP_006769694.1 CDS O3M_10225 NC_018650.1 2136753 2137148 R COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily; inner membrane protein complement(2136753..2137148) Escherichia coli O104:H4 str. 2009EL-2050 13693591 YP_006769695.1 CDS O3M_10230 NC_018650.1 2137201 2137926 R COG1801 Uncharacterized conserved protein; hypothetical protein complement(2137201..2137926) Escherichia coli O104:H4 str. 2009EL-2050 13693592 YP_006769696.1 CDS O3M_10235 NC_018650.1 2137953 2139263 R COG0582 Integrase; integrase complement(2137953..2139263) Escherichia coli O104:H4 str. 2009EL-2050 13693593 YP_006769697.1 CDS O3M_10240 NC_018650.1 2139319 2139555 R excisionase complement(2139319..2139555) Escherichia coli O104:H4 str. 2009EL-2050 13693594 YP_006769698.1 CDS O3M_10245 NC_018650.1 2139564 2139710 R hypothetical protein complement(2139564..2139710) Escherichia coli O104:H4 str. 2009EL-2050 13693595 YP_006769699.1 CDS O3M_10250 NC_018650.1 2139714 2139956 R hypothetical protein complement(2139714..2139956) Escherichia coli O104:H4 str. 2009EL-2050 13693596 YP_006769700.1 CDS O3M_10255 NC_018650.1 2140041 2140799 R hypothetical protein complement(2140041..2140799) Escherichia coli O104:H4 str. 2009EL-2050 13693597 YP_006769701.1 CDS O3M_10260 NC_018650.1 2140796 2141311 R hypothetical protein complement(2140796..2141311) Escherichia coli O104:H4 str. 2009EL-2050 13693598 YP_006769702.1 CDS O3M_10265 NC_018650.1 2141313 2141861 R EA22-like protein complement(2141313..2141861) Escherichia coli O104:H4 str. 2009EL-2050 13693599 YP_006769703.1 CDS O3M_10270 NC_018650.1 2141858 2142097 R hypothetical protein complement(2141858..2142097) Escherichia coli O104:H4 str. 2009EL-2050 13693600 YP_006769704.1 CDS O3M_10275 NC_018650.1 2142090 2142293 R hypothetical protein complement(2142090..2142293) Escherichia coli O104:H4 str. 2009EL-2050 13693601 YP_006769705.1 CDS O3M_10280 NC_018650.1 2142290 2142652 R CPS-53 (KpLE1) prophage protein complement(2142290..2142652) Escherichia coli O104:H4 str. 2009EL-2050 13693602 YP_006769706.1 CDS O3M_10285 NC_018650.1 2142643 2143179 R COG1896 Predicted hydrolases of HD superfamily; hypothetical protein complement(2142643..2143179) Escherichia coli O104:H4 str. 2009EL-2050 13693603 YP_006769707.1 CDS O3M_10290 NC_018650.1 2143307 2144131 R COG5532 Uncharacterized conserved protein; CPS-53 (KpLE1) prophage protein complement(2143307..2144131) Escherichia coli O104:H4 str. 2009EL-2050 13693604 YP_006769708.1 CDS O3M_10295 NC_018650.1 2145262 2145954 R COG2932 Predicted transcriptional regulator; repressor protein CI complement(2145262..2145954) Escherichia coli O104:H4 str. 2009EL-2050 13693605 YP_006769709.1 CDS O3M_10300 NC_018650.1 2146052 2146312 D COG1396 Predicted transcriptional regulators; hypothetical protein 2146052..2146312 Escherichia coli O104:H4 str. 2009EL-2050 13693606 YP_006769710.1 CDS O3M_10305 NC_018650.1 2146305 2146862 D e14 prophage; nucleic acid-binding protein 2146305..2146862 Escherichia coli O104:H4 str. 2009EL-2050 13693607 YP_006769711.1 CDS O3M_10310 NC_018650.1 2146859 2148004 D COG3646 Uncharacterized phage-encoded protein; hypothetical protein 2146859..2148004 Escherichia coli O104:H4 str. 2009EL-2050 13693608 YP_006769712.1 CDS O3M_10315 NC_018650.1 2148001 2148225 D hypothetical protein 2148001..2148225 Escherichia coli O104:H4 str. 2009EL-2050 13693609 YP_006769713.1 CDS O3M_10320 NC_018650.1 2148222 2149040 D replication protein from phage 2148222..2149040 Escherichia coli O104:H4 str. 2009EL-2050 13693610 YP_006769714.1 CDS O3M_10325 NC_018650.1 2149037 2149531 D hypothetical protein 2149037..2149531 Escherichia coli O104:H4 str. 2009EL-2050 13693611 YP_006769715.1 CDS O3M_10330 NC_018650.1 2149531 2150184 D phage AdoMet-dependent methyltransferase 2149531..2150184 Escherichia coli O104:H4 str. 2009EL-2050 13693612 YP_006769716.1 CDS O3M_10335 NC_018650.1 2150181 2150507 D COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); LexA repressor 2150181..2150507 Escherichia coli O104:H4 str. 2009EL-2050 13693613 YP_006769717.1 CDS O3M_10340 NC_018650.1 2150504 2150899 D COG4570 Holliday junction resolvase; Crossover junction endodeoxyribonuclease 2150504..2150899 Escherichia coli O104:H4 str. 2009EL-2050 13693614 YP_006769718.1 CDS O3M_10345 NC_018650.1 2151062 2151877 D hypothetical protein 2151062..2151877 Escherichia coli O104:H4 str. 2009EL-2050 13693615 YP_006769719.1 CDS O3M_10350 NC_018650.1 2151879 2152874 D hypothetical protein 2151879..2152874 Escherichia coli O104:H4 str. 2009EL-2050 13693616 YP_006769720.1 CDS O3M_10355 NC_018650.1 2152892 2153248 D antitermination protein from phage origin 2152892..2153248 Escherichia coli O104:H4 str. 2009EL-2050 13693617 YP_006769721.1 CDS O3M_10360 NC_018650.1 2153228 2154442 R hypothetical protein complement(2153228..2154442) Escherichia coli O104:H4 str. 2009EL-2050 13693618 YP_006769722.1 CDS O3M_10365 NC_018650.1 2154445 2155620 R COG3081 Nucleoid-associated protein; hypothetical protein complement(2154445..2155620) Escherichia coli O104:H4 str. 2009EL-2050 13693619 YP_006769723.1 CDS O3M_10370 NC_018650.1 2155887 2156084 D hypothetical protein 2155887..2156084 Escherichia coli O104:H4 str. 2009EL-2050 13693620 YP_006769724.1 CDS O3M_10375 NC_018650.1 2156345 2156932 D COG2207 AraC-type DNA-binding domain-containing proteins; regulatory protein 2156345..2156932 Escherichia coli O104:H4 str. 2009EL-2050 13693621 YP_006769725.1 CDS O3M_10380 NC_018650.1 2157699 2159660 D hypothetical protein 2157699..2159660 Escherichia coli O104:H4 str. 2009EL-2050 13693625 YP_006769726.1 CDS O3M_10385 NC_018650.1 2159796 2159990 D hypothetical protein 2159796..2159990 Escherichia coli O104:H4 str. 2009EL-2050 13693626 YP_006769727.1 CDS O3M_10390 NC_018650.1 2160016 2160285 D hypothetical protein 2160016..2160285 Escherichia coli O104:H4 str. 2009EL-2050 13693627 YP_006769728.1 CDS O3M_10395 NC_018650.1 2160361 2160576 D lysis protein S of prophage CP-933V 2160361..2160576 Escherichia coli O104:H4 str. 2009EL-2050 13693628 YP_006769729.1 CDS O3M_10400 NC_018650.1 2160581 2160925 D hypothetical protein 2160581..2160925 Escherichia coli O104:H4 str. 2009EL-2050 13693629 YP_006769730.1 CDS O3M_10405 NC_018650.1 2160976 2161509 D COG3772 Phage-related lysozyme (muraminidase); phage-related lysozyme (muraminidase) 2160976..2161509 Escherichia coli O104:H4 str. 2009EL-2050 13693630 YP_006769731.1 CDS O3M_10410 NC_018650.1 2161633 2161806 D hypothetical protein 2161633..2161806 Escherichia coli O104:H4 str. 2009EL-2050 13693631 YP_006769732.1 CDS O3M_10415 NC_018650.1 2161808 2162275 D endopeptidase 2161808..2162275 Escherichia coli O104:H4 str. 2009EL-2050 13693632 YP_006769733.1 CDS O3M_10420 NC_018650.1 2162626 2162766 D hypothetical protein 2162626..2162766 Escherichia coli O104:H4 str. 2009EL-2050 13693633 YP_006769734.1 CDS O3M_10425 NC_018650.1 2162899 2163084 R hypothetical protein complement(2162899..2163084) Escherichia coli O104:H4 str. 2009EL-2050 13693634 YP_006769735.1 CDS O3M_10430 NC_018650.1 2163100 2163255 R hypothetical protein complement(2163100..2163255) Escherichia coli O104:H4 str. 2009EL-2050 13693635 YP_006769736.1 CDS O3M_10435 NC_018650.1 2163479 2164027 D COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; prophage Qin DNA packaging protein NU1-like protein 2163479..2164027 Escherichia coli O104:H4 str. 2009EL-2050 13693636 YP_006769737.1 CDS O3M_10450 NC_018650.1 2165912 2166118 D head completion protein 2165912..2166118 Escherichia coli O104:H4 str. 2009EL-2050 13693637 YP_006769738.1 CDS O3M_10455 NC_018650.1 2166115 2167707 D COG5511 Bacteriophage capsid protein; head protein Gp4 2166115..2167707 Escherichia coli O104:H4 str. 2009EL-2050 13693638 YP_006769739.1 CDS O3M_10460 NC_018650.1 2167697 2169202 D COG0616 Periplasmic serine proteases (ClpP class); head-tail preconnector protein GP5 2167697..2169202 Escherichia coli O104:H4 str. 2009EL-2050 13693639 YP_006769740.1 CDS O3M_10465 NC_018650.1 2169239 2169586 D major capsid protein D 2169239..2169586 Escherichia coli O104:H4 str. 2009EL-2050 13693640 YP_006769741.1 CDS O3M_10470 NC_018650.1 2169644 2170672 D major head protein 2169644..2170672 Escherichia coli O104:H4 str. 2009EL-2050 13693641 YP_006769742.1 CDS O3M_10475 NC_018650.1 2170725 2171093 D DNA packaging protein from phage origin 2170725..2171093 Escherichia coli O104:H4 str. 2009EL-2050 13693642 YP_006769743.1 CDS O3M_10480 NC_018650.1 2171086 2171439 D tail attachment protein 2171086..2171439 Escherichia coli O104:H4 str. 2009EL-2050 13693643 YP_006769744.1 CDS O3M_10485 NC_018650.1 2171455 2172033 D minor tail protein 2171455..2172033 Escherichia coli O104:H4 str. 2009EL-2050 13693644 YP_006769745.1 CDS O3M_10490 NC_018650.1 2172030 2172425 D COG0477 Permeases of the major facilitator superfamily; minor tail protein U 2172030..2172425 Escherichia coli O104:H4 str. 2009EL-2050 13693645 YP_006769746.1 CDS O3M_10495 NC_018650.1 2172433 2173173 D COG5492 Bacterial surface proteins containing Ig-like domains; major tail protein V 2172433..2173173 Escherichia coli O104:H4 str. 2009EL-2050 13693646 YP_006769747.1 CDS O3M_10500 NC_018650.1 2173189 2173611 D minor tail protein 2173189..2173611 Escherichia coli O104:H4 str. 2009EL-2050 13693647 YP_006769748.1 CDS O3M_10505 NC_018650.1 2173593 2174027 D minor tail protein T 2173593..2174027 Escherichia coli O104:H4 str. 2009EL-2050 13693648 YP_006769749.1 CDS O3M_10510 NC_018650.1 2174020 2176551 D minor tail protein H 2174020..2176551 Escherichia coli O104:H4 str. 2009EL-2050 13693649 YP_006769750.1 CDS O3M_10515 NC_018650.1 2176579 2176908 D COG4718 Phage-related protein; minor tail protein M 2176579..2176908 Escherichia coli O104:H4 str. 2009EL-2050 13693650 YP_006769751.1 CDS O3M_10520 NC_018650.1 2176908 2177606 D COG4672 Phage-related protein; minor tail protein 2176908..2177606 Escherichia coli O104:H4 str. 2009EL-2050 13693651 YP_006769752.1 CDS O3M_10525 NC_018650.1 2177611 2178354 D COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; NLP/P60 protein 2177611..2178354 Escherichia coli O104:H4 str. 2009EL-2050 13693652 YP_006769753.1 CDS O3M_10530 NC_018650.1 2178252 2178923 D COG4723 Phage-related protein, tail component; tail assembly protein I 2178252..2178923 Escherichia coli O104:H4 str. 2009EL-2050 13693653 YP_006769754.1 CDS O3M_10535 NC_018650.1 2178984 2182463 D COG4733 Phage-related protein, tail component; Host specificity protein J 2178984..2182463 Escherichia coli O104:H4 str. 2009EL-2050 13693654 YP_006769755.1 CDS O3M_10540 NC_018650.1 2182531 2183130 D outer membrane Lom 2182531..2183130 Escherichia coli O104:H4 str. 2009EL-2050 13693655 YP_006769756.1 CDS O3M_10545 NC_018650.1 2183779 2184918 R hypothetical protein complement(2183779..2184918) Escherichia coli O104:H4 str. 2009EL-2050 13693656 YP_006769757.1 CDS O3M_10550 NC_018650.1 2184917 2186452 D tail fiber protein 2184917..2186452 Escherichia coli O104:H4 str. 2009EL-2050 13693657 YP_006769758.1 CDS O3M_10555 NC_018650.1 2186452 2187036 D Qin prophage; tail fiber chaperone 2186452..2187036 Escherichia coli O104:H4 str. 2009EL-2050 13693658 YP_006769759.1 CDS O3M_10560 NC_018650.1 2187152 2187400 R DNA-damage-inducible protein complement(2187152..2187400) Escherichia coli O104:H4 str. 2009EL-2050 13693659 YP_006769760.1 CDS O3M_10565 NC_018650.1 2187497 2187673 D hypothetical protein 2187497..2187673 Escherichia coli O104:H4 str. 2009EL-2050 13693660 YP_006769761.1 CDS O3M_10570 NC_018650.1 2187755 2188321 R COG1335 Amidases related to nicotinamidase; hydrolase complement(2187755..2188321) Escherichia coli O104:H4 str. 2009EL-2050 13693661 YP_006769762.1 CDS aspS NC_018650.1 2188631 2190403 D COG0173 Aspartyl-tRNA synthetase; aspartyl-tRNA synthetase 2188631..2190403 Escherichia coli O104:H4 str. 2009EL-2050 13693662 YP_006769763.1 CDS nudB NC_018650.1 2190405 2190848 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; dihydroneopterin triphosphate pyrophosphatase 2190405..2190848 Escherichia coli O104:H4 str. 2009EL-2050 13693663 YP_006769764.1 CDS O3M_10585 NC_018650.1 2190877 2191617 D COG0217 Uncharacterized conserved protein; hypothetical protein 2190877..2191617 Escherichia coli O104:H4 str. 2009EL-2050 13693664 YP_006769765.1 CDS ruvC NC_018650.1 2191652 2192173 D COG0817 Holliday junction resolvasome, endonuclease subunit; Holliday junction resolvase 2191652..2192173 Escherichia coli O104:H4 str. 2009EL-2050 13693665 YP_006769766.1 CDS O3M_10595 NC_018650.1 2192175 2192777 R hypothetical protein complement(2192175..2192777) Escherichia coli O104:H4 str. 2009EL-2050 13693666 YP_006769767.1 CDS ruvA NC_018650.1 2193052 2193663 D COG0632 Holliday junction resolvasome, DNA-binding subunit; Holliday junction DNA helicase RuvA 2193052..2193663 Escherichia coli O104:H4 str. 2009EL-2050 13693667 YP_006769768.1 CDS ruvB NC_018650.1 2193672 2194682 D COG2255 Holliday junction resolvasome, helicase subunit; Holliday junction DNA helicase RuvB 2193672..2194682 Escherichia coli O104:H4 str. 2009EL-2050 13693668 YP_006769769.1 CDS znuB NC_018650.1 2194829 2195614 R COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; high-affinity zinc transporter membrane protein complement(2194829..2195614) Escherichia coli O104:H4 str. 2009EL-2050 13693669 YP_006769770.1 CDS znuC NC_018650.1 2195611 2196366 R COG1121 ABC-type Mn/Zn transport systems, ATPase component; high-affinity zinc transporter ATPase complement(2195611..2196366) Escherichia coli O104:H4 str. 2009EL-2050 13693670 YP_006769771.1 CDS znuA NC_018650.1 2196445 2197377 D COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin; high-affinity zinc transporter periplasmic protein 2196445..2197377 Escherichia coli O104:H4 str. 2009EL-2050 13693671 YP_006769772.1 CDS O3M_10625 NC_018650.1 2197393 2198715 D COG0739 Membrane proteins related to metalloendopeptidases; peptidase 2197393..2198715 Escherichia coli O104:H4 str. 2009EL-2050 13693672 YP_006769773.1 CDS O3M_10630 NC_018650.1 2198835 2199806 D COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2198835..2199806 Escherichia coli O104:H4 str. 2009EL-2050 13693673 YP_006769774.1 CDS O3M_10635 NC_018650.1 2199937 2201379 R COG0469 Pyruvate kinase; pyruvate kinase complement(2199937..2201379) Escherichia coli O104:H4 str. 2009EL-2050 13693674 YP_006769775.1 CDS O3M_10640 NC_018650.1 2201507 2202376 R COG1737 Transcriptional regulators; DNA-binding transcriptional regulator HexR complement(2201507..2202376) Escherichia coli O104:H4 str. 2009EL-2050 13693675 YP_006769776.1 CDS O3M_10645 NC_018650.1 2202399 2202548 D hypothetical protein 2202399..2202548 Escherichia coli O104:H4 str. 2009EL-2050 13693676 YP_006769777.1 CDS O3M_10650 NC_018650.1 2202714 2204189 D COG0364 Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 2202714..2204189 Escherichia coli O104:H4 str. 2009EL-2050 13693677 YP_006769778.1 CDS O3M_10655 NC_018650.1 2204424 2206235 D COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; phosphogluconate dehydratase 2204424..2206235 Escherichia coli O104:H4 str. 2009EL-2050 13693678 YP_006769779.1 CDS O3M_10660 NC_018650.1 2206272 2206913 D COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2206272..2206913 Escherichia coli O104:H4 str. 2009EL-2050 13693679 YP_006769780.1 CDS purT NC_018650.1 2206969 2208147 R COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase); phosphoribosylglycinamide formyltransferase 2 complement(2206969..2208147) Escherichia coli O104:H4 str. 2009EL-2050 13693680 YP_006769781.1 CDS O3M_10670 NC_018650.1 2208281 2208571 D COG3141 Uncharacterized protein conserved in bacteria; DNA damage-inducible protein YebG 2208281..2208571 Escherichia coli O104:H4 str. 2009EL-2050 13693681 YP_006769782.1 CDS O3M_10675 NC_018650.1 2208638 2208994 D hypothetical protein 2208638..2208994 Escherichia coli O104:H4 str. 2009EL-2050 13693682 YP_006769783.1 CDS O3M_10680 NC_018650.1 2209151 2209261 R hypothetical protein complement(2209151..2209261) Escherichia coli O104:H4 str. 2009EL-2050 13693683 YP_006769784.1 CDS O3M_10685 NC_018650.1 2209321 2209980 D COG2979 Uncharacterized protein conserved in bacteria; hypothetical protein 2209321..2209980 Escherichia coli O104:H4 str. 2009EL-2050 13693684 YP_006769785.1 CDS O3M_10690 NC_018650.1 2210189 2212249 D COG1770 Protease II; protease 2 2210189..2212249 Escherichia coli O104:H4 str. 2009EL-2050 13693685 YP_006769786.1 CDS O3M_10695 NC_018650.1 2212246 2212908 R COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; exodeoxyribonuclease X complement(2212246..2212908) Escherichia coli O104:H4 str. 2009EL-2050 13693686 YP_006769787.1 CDS O3M_10700 NC_018650.1 2212932 2213588 R COG0388 Predicted amidohydrolase; carbon-nitrogen family hydrolase complement(2212932..2213588) Escherichia coli O104:H4 str. 2009EL-2050 13693687 YP_006769788.1 CDS O3M_10705 NC_018650.1 2213690 2213920 R DNA polymerase III subunit theta complement(2213690..2213920) Escherichia coli O104:H4 str. 2009EL-2050 13693688 YP_006769789.1 CDS O3M_10710 NC_018650.1 2214059 2214433 D COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; hypothetical protein 2214059..2214433 Escherichia coli O104:H4 str. 2009EL-2050 13693689 YP_006769790.1 CDS O3M_10715 NC_018650.1 2214437 2215309 D COG1276 Putative copper export protein; copper resistance protein D 2214437..2215309 Escherichia coli O104:H4 str. 2009EL-2050 13693690 YP_006769791.1 CDS O3M_10720 NC_018650.1 2215322 2215663 D hypothetical protein 2215322..2215663 Escherichia coli O104:H4 str. 2009EL-2050 13693691 YP_006769792.1 CDS pphA NC_018650.1 2216059 2216715 D COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; serine/threonine protein phosphatase 1 2216059..2216715 Escherichia coli O104:H4 str. 2009EL-2050 13693692 YP_006769793.1 CDS O3M_10730 NC_018650.1 2216716 2216907 R hypothetical protein complement(2216716..2216907) Escherichia coli O104:H4 str. 2009EL-2050 13693693 YP_006769794.1 CDS O3M_10735 NC_018650.1 2217012 2217248 R hypothetical protein complement(2217012..2217248) Escherichia coli O104:H4 str. 2009EL-2050 13693694 YP_006769795.1 CDS yebU NC_018650.1 2217366 2218805 R COG0144 tRNA and rRNA cytosine-C5-methylases; rRNA (cytosine-C(5)-)-methyltransferase RsmF complement(2217366..2218805) Escherichia coli O104:H4 str. 2009EL-2050 13693695 YP_006769796.1 CDS O3M_10745 NC_018650.1 2218885 2221518 R COG3008 Paraquat-inducible protein B; mce-like protein complement(2218885..2221518) Escherichia coli O104:H4 str. 2009EL-2050 13693696 YP_006769797.1 CDS O3M_10750 NC_018650.1 2221487 2222770 R COG2995 Uncharacterized paraquat-inducible protein A; hypothetical protein complement(2221487..2222770) Escherichia coli O104:H4 str. 2009EL-2050 13693697 YP_006769798.1 CDS O3M_10755 NC_018650.1 2222900 2223397 D COG1956 GAF domain-containing protein; hypothetical protein 2222900..2223397 Escherichia coli O104:H4 str. 2009EL-2050 13693698 YP_006769799.1 CDS O3M_10760 NC_018650.1 2223494 2224192 D COG3109 Activator of osmoprotectant transporter ProP; ProP expression regulator 2223494..2224192 Escherichia coli O104:H4 str. 2009EL-2050 13693699 YP_006769800.1 CDS O3M_10765 NC_018650.1 2224212 2226260 D COG0793 Periplasmic protease; carboxy-terminal protease 2224212..2226260 Escherichia coli O104:H4 str. 2009EL-2050 13693700 YP_006769801.1 CDS O3M_10770 NC_018650.1 2226452 2227333 D COG0501 Zn-dependent protease with chaperone function; heat shock protein HtpX 2226452..2227333 Escherichia coli O104:H4 str. 2009EL-2050 13693701 YP_006769802.1 CDS O3M_10775 NC_018650.1 2227379 2228752 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2227379..2228752) Escherichia coli O104:H4 str. 2009EL-2050 13688615 YP_006769803.1 CDS O3M_10780 NC_018650.1 2228929 2229720 D COG1414 Transcriptional regulator; DNA-binding transcriptional regulator KdgR 2228929..2229720 Escherichia coli O104:H4 str. 2009EL-2050 13688616 YP_006769804.1 CDS O3M_10785 NC_018650.1 2229863 2230078 R hypothetical protein complement(2229863..2230078) Escherichia coli O104:H4 str. 2009EL-2050 13688617 YP_006769805.1 CDS O3M_10790 NC_018650.1 2230261 2230404 D PhoPQ regulatory protein 2230261..2230404 Escherichia coli O104:H4 str. 2009EL-2050 13688618 YP_006769806.1 CDS O3M_10795 NC_018650.1 2230479 2230766 D hypothetical protein 2230479..2230766 Escherichia coli O104:H4 str. 2009EL-2050 13688619 YP_006769807.1 CDS O3M_10800 NC_018650.1 2231436 2231579 D hypothetical protein 2231436..2231579 Escherichia coli O104:H4 str. 2009EL-2050 13688620 YP_006769808.1 CDS O3M_10805 NC_018650.1 2231592 2231801 D COG1278 Cold shock proteins; cold-shock protein 2231592..2231801 Escherichia coli O104:H4 str. 2009EL-2050 13688621 YP_006769809.1 CDS rrmA NC_018650.1 2231967 2232776 D COG0500 SAM-dependent methyltransferases; 23S rRNA methyltransferase A 2231967..2232776 Escherichia coli O104:H4 str. 2009EL-2050 13688622 YP_006769810.1 CDS O3M_10815 NC_018650.1 2232773 2233339 R COG1971 Predicted membrane protein; hypothetical protein complement(2232773..2233339) Escherichia coli O104:H4 str. 2009EL-2050 13688623 YP_006769811.1 CDS O3M_10820 NC_018650.1 2233768 2234226 R COG4811 Predicted membrane protein; hypothetical protein complement(2233768..2234226) Escherichia coli O104:H4 str. 2009EL-2050 13688624 YP_006769812.1 CDS O3M_10825 NC_018650.1 2234281 2235141 R COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose-specific transporter subunit IID complement(2234281..2235141) Escherichia coli O104:H4 str. 2009EL-2050 13688625 YP_006769813.1 CDS O3M_10830 NC_018650.1 2235145 2235945 R COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose-specific transporter subunit IIC complement(2235145..2235945) Escherichia coli O104:H4 str. 2009EL-2050 13688626 YP_006769814.1 CDS O3M_10835 NC_018650.1 2236008 2236979 R COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose-specific transporter subunit IIAB complement(2236008..2236979) Escherichia coli O104:H4 str. 2009EL-2050 13688627 YP_006769815.1 CDS O3M_10840 NC_018650.1 2237442 2238998 D COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 2237442..2238998 Escherichia coli O104:H4 str. 2009EL-2050 13688628 YP_006769816.1 CDS O3M_10845 NC_018650.1 2239002 2240600 R COG2200 FOG: EAL domain; phosphodiesterase complement(2239002..2240600) Escherichia coli O104:H4 str. 2009EL-2050 13688629 YP_006769817.1 CDS O3M_10850 NC_018650.1 2240731 2242095 R COG1760 L-serine deaminase; L-serine deaminase complement(2240731..2242095) Escherichia coli O104:H4 str. 2009EL-2050 13688630 YP_006769818.1 CDS O3M_10855 NC_018650.1 2242279 2242857 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase complement(2242279..2242857) Escherichia coli O104:H4 str. 2009EL-2050 13688631 YP_006769819.1 CDS pabB NC_018650.1 2242861 2244222 R COG0147 Anthranilate/para-aminobenzoate synthases component I; aminodeoxychorismate synthase subunit I complement(2242861..2244222) Escherichia coli O104:H4 str. 2009EL-2050 13688632 YP_006769820.1 CDS O3M_10865 NC_018650.1 2244296 2244475 D COG3140 Uncharacterized protein conserved in bacteria; hypothetical protein 2244296..2244475 Escherichia coli O104:H4 str. 2009EL-2050 13688633 YP_006769821.1 CDS O3M_10870 NC_018650.1 2244595 2244954 R hypothetical protein complement(2244595..2244954) Escherichia coli O104:H4 str. 2009EL-2050 13688634 YP_006769822.1 CDS O3M_10875 NC_018650.1 2245317 2245661 R COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein complement(2245317..2245661) Escherichia coli O104:H4 str. 2009EL-2050 13688635 YP_006769823.1 CDS O3M_10880 NC_018650.1 2245793 2247703 D COG1199 Rad3-related DNA helicases; Helicase c2 2245793..2247703 Escherichia coli O104:H4 str. 2009EL-2050 13688636 YP_006769824.1 CDS O3M_10885 NC_018650.1 2247761 2248456 D COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; peptidase 2247761..2248456 Escherichia coli O104:H4 str. 2009EL-2050 13688637 YP_006769825.1 CDS O3M_10890 NC_018650.1 2248496 2249077 D COG3065 Starvation-inducible outer membrane lipoprotein; outer membrane lipoprotein 2248496..2249077 Escherichia coli O104:H4 str. 2009EL-2050 13688638 YP_006769826.1 CDS O3M_10895 NC_018650.1 2249282 2250967 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; long-chain-fatty-acid--CoA ligase 2249282..2250967 Escherichia coli O104:H4 str. 2009EL-2050 13688639 YP_006769827.1 CDS O3M_10900 NC_018650.1 2251037 2252164 D COG0349 Ribonuclease D; ribonuclease D 2251037..2252164 Escherichia coli O104:H4 str. 2009EL-2050 13688640 YP_006769828.1 CDS O3M_10905 NC_018650.1 2252218 2253183 R COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; oxidoreductase complement(2252218..2253183) Escherichia coli O104:H4 str. 2009EL-2050 13688641 YP_006769829.1 CDS O3M_10910 NC_018650.1 2253239 2254363 R COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; dioxygenase subunit alpha yeaW complement(2253239..2254363) Escherichia coli O104:H4 str. 2009EL-2050 13688642 YP_006769830.1 CDS O3M_10915 NC_018650.1 2254395 2256005 R COG1292 Choline-glycine betaine transporter; transporter complement(2254395..2256005) Escherichia coli O104:H4 str. 2009EL-2050 13688643 YP_006769831.1 CDS O3M_10920 NC_018650.1 2256256 2257341 R COG0473 Isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase complement(2256256..2257341) Escherichia coli O104:H4 str. 2009EL-2050 13688644 YP_006769832.1 CDS O3M_10925 NC_018650.1 2257444 2258367 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 2257444..2258367 Escherichia coli O104:H4 str. 2009EL-2050 13688645 YP_006769833.1 CDS O3M_10930 NC_018650.1 2258494 2259132 D COG1280 Putative threonine efflux protein; leucine export protein LeuE 2258494..2259132 Escherichia coli O104:H4 str. 2009EL-2050 13688646 YP_006769834.1 CDS O3M_10935 NC_018650.1 2259305 2259664 D COG3615 Uncharacterized protein/domain, possibly involved in tellurite resistance; hypothetical protein 2259305..2259664 Escherichia coli O104:H4 str. 2009EL-2050 13688647 YP_006769835.1 CDS O3M_10940 NC_018650.1 2259668 2259856 D hypothetical protein 2259668..2259856 Escherichia coli O104:H4 str. 2009EL-2050 13688648 YP_006769836.1 CDS O3M_10945 NC_018650.1 2260311 2261519 D COG0675 Transposase and inactivated derivatives; transposase 2260311..2261519 Escherichia coli O104:H4 str. 2009EL-2050 13688649 YP_006769837.1 CDS O3M_10950 NC_018650.1 2261746 2261994 D COG2261 Predicted membrane protein; hypothetical protein 2261746..2261994 Escherichia coli O104:H4 str. 2009EL-2050 13688650 YP_006769838.1 CDS O3M_10955 NC_018650.1 2262053 2262127 R hypothetical protein complement(2262053..2262127) Escherichia coli O104:H4 str. 2009EL-2050 13688651 YP_006769839.1 CDS O3M_10960 NC_018650.1 2262261 2263286 R COG2199 FOG: GGDEF domain; diguanylate cyclase complement(2262261..2263286) Escherichia coli O104:H4 str. 2009EL-2050 13688652 YP_006769840.1 CDS O3M_10965 NC_018650.1 2263469 2263723 D COG3042 Putative hemolysin; lipoprotein 2263469..2263723 Escherichia coli O104:H4 str. 2009EL-2050 13688653 YP_006769841.1 CDS O3M_10970 NC_018650.1 2263745 2264092 R COG3189 Uncharacterized conserved protein; hypothetical protein complement(2263745..2264092) Escherichia coli O104:H4 str. 2009EL-2050 13688654 YP_006769842.1 CDS O3M_10975 NC_018650.1 2264147 2265328 R COG2807 Cyanate permease; transporter complement(2264147..2265328) Escherichia coli O104:H4 str. 2009EL-2050 13688655 YP_006769843.1 CDS O3M_10980 NC_018650.1 2265425 2266246 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator, ARAC-type 2265425..2266246 Escherichia coli O104:H4 str. 2009EL-2050 13688656 YP_006769844.1 CDS O3M_10985 NC_018650.1 2266111 2266653 R COG2707 Predicted membrane protein; inner membrane protein complement(2266111..2266653) Escherichia coli O104:H4 str. 2009EL-2050 13688657 YP_006769845.1 CDS O3M_10990 NC_018650.1 2266775 2266927 D hypothetical protein 2266775..2266927 Escherichia coli O104:H4 str. 2009EL-2050 13688658 YP_006769846.1 CDS O3M_10995 NC_018650.1 2266928 2267431 R COG2606 Uncharacterized conserved protein; hypothetical protein complement(2266928..2267431) Escherichia coli O104:H4 str. 2009EL-2050 13688659 YP_006769847.1 CDS O3M_11000 NC_018650.1 2267474 2268964 R COG2199 FOG: GGDEF domain; diguanylate cyclase complement(2267474..2268964) Escherichia coli O104:H4 str. 2009EL-2050 13688660 YP_006769848.1 CDS O3M_11005 NC_018650.1 2269145 2270620 R COG2199 FOG: GGDEF domain; hypothetical protein complement(2269145..2270620) Escherichia coli O104:H4 str. 2009EL-2050 13688661 YP_006769849.1 CDS O3M_11010 NC_018650.1 2270767 2272050 R COG2718 Uncharacterized conserved protein; hypothetical protein complement(2270767..2272050) Escherichia coli O104:H4 str. 2009EL-2050 13688662 YP_006769850.1 CDS O3M_11015 NC_018650.1 2272163 2274097 R COG2766 Putative Ser protein kinase; PrkA family serine protein kinase complement(2272163..2274097) Escherichia coli O104:H4 str. 2009EL-2050 13688663 YP_006769851.1 CDS O3M_11020 NC_018650.1 2274533 2275279 D COG3713 Outer membrane protein V; MltA-interacting protein 2274533..2275279 Escherichia coli O104:H4 str. 2009EL-2050 13688664 YP_006769852.1 CDS O3M_11025 NC_018650.1 2275369 2276223 D COG0656 Aldo/keto reductases, related to diketogulonate reductase; oxidoreductase 2275369..2276223 Escherichia coli O104:H4 str. 2009EL-2050 13688665 YP_006769853.1 CDS O3M_11030 NC_018650.1 2276274 2277158 R COG0676 Uncharacterized enzymes related to aldose 1-epimerase; aldose 1-epimerase complement(2276274..2277158) Escherichia coli O104:H4 str. 2009EL-2050 13688666 YP_006769854.1 CDS gapA NC_018650.1 2277242 2278237 R COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase complement(2277242..2278237) Escherichia coli O104:H4 str. 2009EL-2050 13688667 YP_006769855.1 CDS O3M_11040 NC_018650.1 2278579 2278992 D COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; methionine sulfoxide reductase B 2278579..2278992 Escherichia coli O104:H4 str. 2009EL-2050 13688668 YP_006769856.1 CDS O3M_11045 NC_018650.1 2279034 2279306 D COG3139 Uncharacterized protein conserved in bacteria; hypothetical protein 2279034..2279306 Escherichia coli O104:H4 str. 2009EL-2050 13688669 YP_006769857.1 CDS O3M_11050 NC_018650.1 2279676 2280752 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase zinc-binding dehydrogenase family protein 2279676..2280752 Escherichia coli O104:H4 str. 2009EL-2050 13688670 YP_006769858.1 CDS O3M_11055 NC_018650.1 2280779 2282158 D MFS superfamily protein; COG0477 Permeases of the major facilitator superfamily; transporter 2280779..2282158 Escherichia coli O104:H4 str. 2009EL-2050 13688671 YP_006769859.1 CDS O3M_11060 NC_018650.1 2282175 2283218 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; iditol dehydrogenase 2282175..2283218 Escherichia coli O104:H4 str. 2009EL-2050 13688672 YP_006769860.1 CDS O3M_11065 NC_018650.1 2283239 2284075 D COG0191 Fructose/tagatose bisphosphate aldolase; aldolase 2283239..2284075 Escherichia coli O104:H4 str. 2009EL-2050 13688673 YP_006769861.1 CDS O3M_11070 NC_018650.1 2284080 2285027 D COG0524 Sugar kinases, ribokinase family; kinase 2284080..2285027 Escherichia coli O104:H4 str. 2009EL-2050 13688674 YP_006769862.1 CDS O3M_11075 NC_018650.1 2285037 2286017 D COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 2285037..2286017 Escherichia coli O104:H4 str. 2009EL-2050 13688675 YP_006769863.1 CDS O3M_11080 NC_018650.1 2286154 2286912 D COG1349 Transcriptional regulators of sugar metabolism; DEOR-type transcriptional regulator 2286154..2286912 Escherichia coli O104:H4 str. 2009EL-2050 13688676 YP_006769864.1 CDS O3M_11085 NC_018650.1 2287029 2288387 D MFS superfamily protein; COG0477 Permeases of the major facilitator superfamily; transporter 2287029..2288387 Escherichia coli O104:H4 str. 2009EL-2050 13688677 YP_006769865.1 CDS O3M_11090 NC_018650.1 2288480 2289121 R COG1335 Amidases related to nicotinamidase; nicotinamidase/pyrazinamidase complement(2288480..2289121) Escherichia coli O104:H4 str. 2009EL-2050 13688678 YP_006769866.1 CDS ansA NC_018650.1 2289132 2290148 R COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; asparaginase complement(2289132..2290148) Escherichia coli O104:H4 str. 2009EL-2050 13688679 YP_006769867.1 CDS O3M_11100 NC_018650.1 2290315 2292171 R COG0616 Periplasmic serine proteases (ClpP class); protease 4 complement(2290315..2292171) Escherichia coli O104:H4 str. 2009EL-2050 13688680 YP_006769868.1 CDS O3M_11105 NC_018650.1 2292332 2292883 D COG0778 Nitroreductase; oxidoreductase 2292332..2292883 Escherichia coli O104:H4 str. 2009EL-2050 13688681 YP_006769869.1 CDS O3M_11110 NC_018650.1 2293000 2294043 D COG0709 Selenophosphate synthase; selenophosphate synthetase 2293000..2294043 Escherichia coli O104:H4 str. 2009EL-2050 13688682 YP_006769870.1 CDS O3M_11115 NC_018650.1 2294048 2296009 D COG0550 Topoisomerase IA; DNA topoisomerase III 2294048..2296009 Escherichia coli O104:H4 str. 2009EL-2050 13688683 YP_006769871.1 CDS O3M_11120 NC_018650.1 2296137 2296664 D hypothetical protein 2296137..2296664 Escherichia coli O104:H4 str. 2009EL-2050 13688684 YP_006769872.1 CDS O3M_11125 NC_018650.1 2296710 2297690 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 2296710..2297690 Escherichia coli O104:H4 str. 2009EL-2050 13688685 YP_006769873.1 CDS O3M_11130 NC_018650.1 2297936 2298376 D hypothetical protein 2297936..2298376 Escherichia coli O104:H4 str. 2009EL-2050 13688686 YP_006769874.1 CDS O3M_11135 NC_018650.1 2298493 2299836 R COG0334 Glutamate dehydrogenase/leucine dehydrogenase; glutamate dehydrogenase complement(2298493..2299836) Escherichia coli O104:H4 str. 2009EL-2050 13688687 YP_006769875.1 CDS O3M_11140 NC_018650.1 2300072 2300344 D hypothetical protein 2300072..2300344 Escherichia coli O104:H4 str. 2009EL-2050 13688688 YP_006769876.1 CDS O3M_11145 NC_018650.1 2300310 2300717 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase complement(2300310..2300717) Escherichia coli O104:H4 str. 2009EL-2050 13688689 YP_006769877.1 CDS O3M_11150 NC_018650.1 2300804 2301424 D COG0558 Phosphatidylglycerophosphate synthase; phosphatidyl transferase, inner membrane protein 2300804..2301424 Escherichia coli O104:H4 str. 2009EL-2050 13688690 YP_006769878.1 CDS O3M_11155 NC_018650.1 2301433 2302740 R COG2897 Rhodanese-related sulfurtransferase; thiosulfate sulfur transferase / thiosulfate binding protein complement(2301433..2302740) Escherichia coli O104:H4 str. 2009EL-2050 13688691 YP_006769879.1 CDS O3M_11160 NC_018650.1 2302807 2303460 R COG4136 ABC-type uncharacterized transport system, ATPase component; transporter subunit complement(2302807..2303460) Escherichia coli O104:H4 str. 2009EL-2050 13688692 YP_006769880.1 CDS O3M_11165 NC_018650.1 2303460 2304995 R COG4135 ABC-type uncharacterized transport system, permease component; ABC transporter membrane protein complement(2303460..2304995) Escherichia coli O104:H4 str. 2009EL-2050 13688693 YP_006769881.1 CDS O3M_11170 NC_018650.1 2304968 2306134 R COG4134 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein complement(2304968..2306134) Escherichia coli O104:H4 str. 2009EL-2050 13688694 YP_006769882.1 CDS O3M_11175 NC_018650.1 2306144 2306692 R COG2128 Uncharacterized conserved protein; carboxymuconolactone decarboxylase family protein complement(2306144..2306692) Escherichia coli O104:H4 str. 2009EL-2050 13688695 YP_006769883.1 CDS O3M_11180 NC_018650.1 2306692 2307399 R COG0398 Uncharacterized conserved protein; inner membrane protein complement(2306692..2307399) Escherichia coli O104:H4 str. 2009EL-2050 13688696 YP_006769884.1 CDS O3M_11185 NC_018650.1 2307413 2308090 R hypothetical protein complement(2307413..2308090) Escherichia coli O104:H4 str. 2009EL-2050 13688697 YP_006769885.1 CDS O3M_11190 NC_018650.1 2308095 2308805 R COG0398 Uncharacterized conserved protein; inner membrane protein complement(2308095..2308805) Escherichia coli O104:H4 str. 2009EL-2050 13688698 YP_006769886.1 CDS O3M_11195 NC_018650.1 2308972 2309778 R COG0708 Exonuclease III; exonuclease III complement(2308972..2309778) Escherichia coli O104:H4 str. 2009EL-2050 13688699 YP_006769887.1 CDS O3M_11200 NC_018650.1 2310224 2311444 D COG4992 Ornithine/acetylornithine aminotransferase; bifunctional succinylornithine transaminase/acetylornithine transaminase 2310224..2311444 Escherichia coli O104:H4 str. 2009EL-2050 13688700 YP_006769888.1 CDS O3M_11205 NC_018650.1 2311441 2312475 D COG3138 Arginine/ornithine N-succinyltransferase beta subunit; arginine succinyltransferase 2311441..2312475 Escherichia coli O104:H4 str. 2009EL-2050 13688701 YP_006769889.1 CDS astD NC_018650.1 2312472 2313950 D COG1012 NAD-dependent aldehyde dehydrogenases; succinylglutamic semialdehyde dehydrogenase 2312472..2313950 Escherichia coli O104:H4 str. 2009EL-2050 13688702 YP_006769890.1 CDS O3M_11215 NC_018650.1 2313947 2315290 D COG3724 Succinylarginine dihydrolase; succinylarginine dihydrolase 2313947..2315290 Escherichia coli O104:H4 str. 2009EL-2050 13688703 YP_006769891.1 CDS O3M_11220 NC_018650.1 2315283 2316251 D COG2988 Succinylglutamate desuccinylase; succinylglutamate desuccinylase 2315283..2316251 Escherichia coli O104:H4 str. 2009EL-2050 13688704 YP_006769892.1 CDS O3M_11225 NC_018650.1 2316581 2317066 D COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; hypothetical protein 2316581..2317066 Escherichia coli O104:H4 str. 2009EL-2050 13688705 YP_006769893.1 CDS O3M_11230 NC_018650.1 2317269 2317844 D COG3758 Uncharacterized protein conserved in bacteria; hypothetical protein 2317269..2317844 Escherichia coli O104:H4 str. 2009EL-2050 13688706 YP_006769894.1 CDS O3M_11235 NC_018650.1 2317804 2318691 R COG0322 Nuclease subunit of the excinuclease complex; nucleotide excision repair endonuclease complement(2317804..2318691) Escherichia coli O104:H4 str. 2009EL-2050 13688707 YP_006769895.1 CDS O3M_11240 NC_018650.1 2318761 2318910 D hypothetical protein 2318761..2318910 Escherichia coli O104:H4 str. 2009EL-2050 13688708 YP_006769896.1 CDS nadE NC_018650.1 2318921 2319748 R COG0171 NAD synthase; NAD synthetase complement(2318921..2319748) Escherichia coli O104:H4 str. 2009EL-2050 13688709 YP_006769897.1 CDS O3M_11250 NC_018650.1 2319950 2320288 D DNA-binding transcriptional activator OsmE 2319950..2320288 Escherichia coli O104:H4 str. 2009EL-2050 13688710 YP_006769898.1 CDS O3M_11255 NC_018650.1 2320587 2320907 D COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2320587..2320907 Escherichia coli O104:H4 str. 2009EL-2050 13688711 YP_006769899.1 CDS O3M_11260 NC_018650.1 2320992 2322350 D COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2320992..2322350 Escherichia coli O104:H4 str. 2009EL-2050 13688712 YP_006769900.1 CDS O3M_11265 NC_018650.1 2322401 2322751 D COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2322401..2322751 Escherichia coli O104:H4 str. 2009EL-2050 13688713 YP_006769901.1 CDS O3M_11270 NC_018650.1 2322759 2323601 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator ChbR 2322759..2323601 Escherichia coli O104:H4 str. 2009EL-2050 13688714 YP_006769902.1 CDS O3M_11275 NC_018650.1 2323706 2325058 D COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; cryptic phospho-beta-glucosidase, NAD(P)-binding protein 2323706..2325058 Escherichia coli O104:H4 str. 2009EL-2050 13688715 YP_006769903.1 CDS O3M_11280 NC_018650.1 2325071 2325829 D COG3394 Uncharacterized protein conserved in bacteria; hypothetical protein 2325071..2325829 Escherichia coli O104:H4 str. 2009EL-2050 13688716 YP_006769904.1 CDS katE NC_018650.1 2325876 2328137 R COG0753 Catalase; hydroperoxidase II complement(2325876..2328137) Escherichia coli O104:H4 str. 2009EL-2050 13688717 YP_006769905.1 CDS O3M_11290 NC_018650.1 2328341 2328583 D cell division modulator 2328341..2328583 Escherichia coli O104:H4 str. 2009EL-2050 13688718 YP_006769906.1 CDS O3M_11295 NC_018650.1 2328872 2329228 D hypothetical protein 2328872..2329228 Escherichia coli O104:H4 str. 2009EL-2050 13688719 YP_006769907.1 CDS O3M_11300 NC_018650.1 2329238 2329675 D hypothetical protein 2329238..2329675 Escherichia coli O104:H4 str. 2009EL-2050 13688720 YP_006769908.1 CDS O3M_11305 NC_018650.1 2329679 2331070 R COG1823 Predicted Na+/dicarboxylate symporter; cation-acid symporter complement(2329679..2331070) Escherichia coli O104:H4 str. 2009EL-2050 13688721 YP_006769909.1 CDS O3M_11310 NC_018650.1 2331203 2331793 R COG1988 Predicted membrane-bound metal-dependent hydrolases; inner membrane protein complement(2331203..2331793) Escherichia coli O104:H4 str. 2009EL-2050 13688722 YP_006769910.1 CDS O3M_11315 NC_018650.1 2331956 2332624 R COG0637 Predicted phosphatase/phosphohexomutase; 2-deoxyglucose-6-phosphatase complement(2331956..2332624) Escherichia coli O104:H4 str. 2009EL-2050 13688723 YP_006769911.1 CDS O3M_11320 NC_018650.1 2332771 2333307 D inner membrane protein 2332771..2333307 Escherichia coli O104:H4 str. 2009EL-2050 13688724 YP_006769912.1 CDS O3M_11325 NC_018650.1 2333348 2334208 R COG3001 Fructosamine-3-kinase; phosphotransferase/kinase complement(2333348..2334208) Escherichia coli O104:H4 str. 2009EL-2050 13688725 YP_006769913.1 CDS O3M_11330 NC_018650.1 2334314 2334604 R hypothetical protein complement(2334314..2334604) Escherichia coli O104:H4 str. 2009EL-2050 13688726 YP_006769914.1 CDS O3M_11335 NC_018650.1 2334705 2335634 R COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); 6-phosphofructokinase complement(2334705..2335634) Escherichia coli O104:H4 str. 2009EL-2050 13688727 YP_006769915.1 CDS O3M_11340 NC_018650.1 2335921 2336679 D COG3137 Putative salt-induced outer membrane protein; hypothetical protein 2335921..2336679 Escherichia coli O104:H4 str. 2009EL-2050 13688728 YP_006769916.1 CDS O3M_11345 NC_018650.1 2336732 2336839 R hypothetical protein complement(2336732..2336839) Escherichia coli O104:H4 str. 2009EL-2050 13688729 YP_006769917.1 CDS thrS NC_018650.1 2339437 2341365 D COG0441 Threonyl-tRNA synthetase; threonyl-tRNA synthetase 2339437..2341365 Escherichia coli O104:H4 str. 2009EL-2050 13688730 YP_006769918.1 CDS infC NC_018650.1 2341477 2341911 D COG0290 Translation initiation factor 3 (IF-3); translation initiation factor IF-3 2341477..2341911 Escherichia coli O104:H4 str. 2009EL-2050 13688731 YP_006769919.1 CDS rpmI NC_018650.1 2342008 2342205 D COG0291 Ribosomal protein L35; 50S ribosomal protein L35 2342008..2342205 Escherichia coli O104:H4 str. 2009EL-2050 13688732 YP_006769920.1 CDS rplT NC_018650.1 2342258 2342614 D COG0292 Ribosomal protein L20; 50S ribosomal protein L20 2342258..2342614 Escherichia coli O104:H4 str. 2009EL-2050 13688733 YP_006769921.1 CDS pheS NC_018650.1 2343064 2344047 D COG0016 Phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 2343064..2344047 Escherichia coli O104:H4 str. 2009EL-2050 13688734 YP_006769922.1 CDS pheT NC_018650.1 2344062 2346449 D COG0073 EMAP domain; phenylalanyl-tRNA synthetase subunit beta 2344062..2346449 Escherichia coli O104:H4 str. 2009EL-2050 13688735 YP_006769923.1 CDS ihfA NC_018650.1 2346454 2346753 D COG0776 Bacterial nucleoid DNA-binding protein; integration host factor subunit alpha 2346454..2346753 Escherichia coli O104:H4 str. 2009EL-2050 13688736 YP_006769924.1 CDS O3M_11395 NC_018650.1 2347055 2347195 R hypothetical protein complement(2347055..2347195) Escherichia coli O104:H4 str. 2009EL-2050 13688737 YP_006769925.1 CDS O3M_11400 NC_018650.1 2347386 2347646 R COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; prophage late promoter activator protein complement(2347386..2347646) Escherichia coli O104:H4 str. 2009EL-2050 13688738 YP_006769926.1 CDS O3M_11405 NC_018650.1 2347879 2349048 D hypothetical protein 2347879..2349048 Escherichia coli O104:H4 str. 2009EL-2050 13688739 YP_006769927.1 CDS O3M_11410 NC_018650.1 2349140 2350249 R COG3500 Phage protein D; phage protein D complement(2349140..2350249) Escherichia coli O104:H4 str. 2009EL-2050 13688740 YP_006769928.1 CDS O3M_11415 NC_018650.1 2350407 2351591 D COG3497 Phage tail sheath protein FI; tail sheath protein 2350407..2351591 Escherichia coli O104:H4 str. 2009EL-2050 13688741 YP_006769929.1 CDS O3M_11420 NC_018650.1 2351591 2352103 D COG3498 Phage tail tube protein FII; tail tube protein 2351591..2352103 Escherichia coli O104:H4 str. 2009EL-2050 13688742 YP_006769930.1 CDS O3M_11425 NC_018650.1 2352158 2352523 D tail protein 2352158..2352523 Escherichia coli O104:H4 str. 2009EL-2050 13688743 YP_006769931.1 CDS O3M_11430 NC_018650.1 2352451 2352687 D phage tail protein 2352451..2352687 Escherichia coli O104:H4 str. 2009EL-2050 13688744 YP_006769932.1 CDS O3M_11435 NC_018650.1 2352674 2355481 D COG5283 Phage-related tail protein; tail protein (modular protein) 2352674..2355481 Escherichia coli O104:H4 str. 2009EL-2050 13688745 YP_006769933.1 CDS O3M_11440 NC_018650.1 2355494 2355982 D COG3499 Phage protein U; tail fiber protein 2355494..2355982 Escherichia coli O104:H4 str. 2009EL-2050 13688746 YP_006769934.1 CDS O3M_11445 NC_018650.1 2356139 2356711 D COG1045 Serine acetyltransferase; acetyltransferase 2356139..2356711 Escherichia coli O104:H4 str. 2009EL-2050 13688747 YP_006769935.1 CDS O3M_11450 NC_018650.1 2356755 2357333 R tail fiber assembly protein complement(2356755..2357333) Escherichia coli O104:H4 str. 2009EL-2050 13688748 YP_006769936.1 CDS O3M_11455 NC_018650.1 2357333 2359465 R COG5301 Phage-related tail fibre protein; side tail fiber protein complement(2357333..2359465) Escherichia coli O104:H4 str. 2009EL-2050 13688749 YP_006769937.1 CDS O3M_11460 NC_018650.1 2359468 2359998 R COG4385 Bacteriophage P2-related tail formation protein; phage tail protein complement(2359468..2359998) Escherichia coli O104:H4 str. 2009EL-2050 13688750 YP_006769938.1 CDS O3M_11465 NC_018650.1 2359991 2360887 R COG3948 Phage-related baseplate assembly protein; baseplate assembly protein complement(2359991..2360887) Escherichia coli O104:H4 str. 2009EL-2050 13688751 YP_006769939.1 CDS O3M_11470 NC_018650.1 2360891 2361241 R COG3628 Phage baseplate assembly protein W; phage baseplate assembly protein complement(2360891..2361241) Escherichia coli O104:H4 str. 2009EL-2050 13688752 YP_006769940.1 CDS O3M_11475 NC_018650.1 2361238 2361819 R COG4540 Phage P2 baseplate assembly protein gpV; baseplate assembly protein complement(2361238..2361819) Escherichia coli O104:H4 str. 2009EL-2050 13688753 YP_006769941.1 CDS O3M_11480 NC_018650.1 2361816 2362460 R phage tail completion protein S complement(2361816..2362460) Escherichia coli O104:H4 str. 2009EL-2050 13688754 YP_006769942.1 CDS O3M_11485 NC_018650.1 2362444 2362911 R Phage tail completion protein R complement(2362444..2362911) Escherichia coli O104:H4 str. 2009EL-2050 13688755 YP_006769943.1 CDS O3M_11490 NC_018650.1 2362935 2364815 R hypothetical protein complement(2362935..2364815) Escherichia coli O104:H4 str. 2009EL-2050 13688756 YP_006769944.1 CDS O3M_11495 NC_018650.1 2364954 2365361 R COG0164 Ribonuclease HII; hypothetical protein complement(2364954..2365361) Escherichia coli O104:H4 str. 2009EL-2050 13688757 YP_006769945.1 CDS O3M_11500 NC_018650.1 2365358 2365750 R endolysin complement(2365358..2365750) Escherichia coli O104:H4 str. 2009EL-2050 13688758 YP_006769946.1 CDS O3M_11505 NC_018650.1 2365747 2366070 R phage holin complement(2365747..2366070) Escherichia coli O104:H4 str. 2009EL-2050 13688759 YP_006769947.1 CDS O3M_11510 NC_018650.1 2366073 2366273 R COG5004 P2-like prophage tail protein X; phage tail protein complement(2366073..2366273) Escherichia coli O104:H4 str. 2009EL-2050 13688760 YP_006769948.1 CDS O3M_11515 NC_018650.1 2366273 2366767 R capsid completion protein complement(2366273..2366767) Escherichia coli O104:H4 str. 2009EL-2050 13688761 YP_006769949.1 CDS O3M_11520 NC_018650.1 2366869 2367669 R terminase, endonuclease subunit complement(2366869..2367669) Escherichia coli O104:H4 str. 2009EL-2050 13688762 YP_006769950.1 CDS O3M_11525 NC_018650.1 2367715 2368767 R major capsid protein complement(2367715..2368767) Escherichia coli O104:H4 str. 2009EL-2050 13688763 YP_006769951.1 CDS O3M_11530 NC_018650.1 2368791 2369627 R capsid scaffolding protein complement(2368791..2369627) Escherichia coli O104:H4 str. 2009EL-2050 13688764 YP_006769952.1 CDS O3M_11535 NC_018650.1 2369782 2371533 D COG5484 Uncharacterized conserved protein; large subunit terminase 2369782..2371533 Escherichia coli O104:H4 str. 2009EL-2050 13688765 YP_006769953.1 CDS O3M_11540 NC_018650.1 2371533 2372579 D COG5518 Bacteriophage capsid portal protein; capsid portal protein 2371533..2372579 Escherichia coli O104:H4 str. 2009EL-2050 13688766 YP_006769954.1 CDS O3M_11545 NC_018650.1 2373091 2373354 R hypothetical protein complement(2373091..2373354) Escherichia coli O104:H4 str. 2009EL-2050 13688767 YP_006769955.1 CDS O3M_11550 NC_018650.1 2373356 2373787 R hypothetical protein complement(2373356..2373787) Escherichia coli O104:H4 str. 2009EL-2050 13688768 YP_006769956.1 CDS O3M_11555 NC_018650.1 2373807 2374121 R plasmid partition protein; modular protein; stability/partitioning protein phage encoded complement(2373807..2374121) Escherichia coli O104:H4 str. 2009EL-2050 13688769 YP_006769957.1 CDS O3M_11560 NC_018650.1 2374126 2375085 R COG0443 Molecular chaperone; prophage stability/partitioning protein complement(2374126..2375085) Escherichia coli O104:H4 str. 2009EL-2050 13688770 YP_006769958.1 CDS O3M_11565 NC_018650.1 2375162 2378002 R phage replication protein complement(2375162..2378002) Escherichia coli O104:H4 str. 2009EL-2050 13688771 YP_006769959.1 CDS O3M_11570 NC_018650.1 2377999 2378388 R hypothetical protein complement(2377999..2378388) Escherichia coli O104:H4 str. 2009EL-2050 13688772 YP_006769960.1 CDS O3M_11575 NC_018650.1 2378461 2378691 R hypothetical protein complement(2378461..2378691) Escherichia coli O104:H4 str. 2009EL-2050 13688773 YP_006769961.1 CDS O3M_11580 NC_018650.1 2379014 2379313 R hypothetical protein complement(2379014..2379313) Escherichia coli O104:H4 str. 2009EL-2050 13688774 YP_006769962.1 CDS O3M_11585 NC_018650.1 2379310 2379555 R COG1846 Transcriptional regulators; hypothetical protein complement(2379310..2379555) Escherichia coli O104:H4 str. 2009EL-2050 13688775 YP_006769963.1 CDS O3M_11590 NC_018650.1 2379552 2379755 R hypothetical protein complement(2379552..2379755) Escherichia coli O104:H4 str. 2009EL-2050 13688776 YP_006769964.1 CDS O3M_11595 NC_018650.1 2379745 2380065 R hypothetical protein complement(2379745..2380065) Escherichia coli O104:H4 str. 2009EL-2050 13688777 YP_006769965.1 CDS O3M_11600 NC_018650.1 2380154 2380267 R hypothetical protein complement(2380154..2380267) Escherichia coli O104:H4 str. 2009EL-2050 13688778 YP_006769966.1 CDS O3M_11605 NC_018650.1 2380264 2380506 R hypothetical protein complement(2380264..2380506) Escherichia coli O104:H4 str. 2009EL-2050 13688779 YP_006769967.1 CDS O3M_11610 NC_018650.1 2380518 2380805 R hypothetical protein complement(2380518..2380805) Escherichia coli O104:H4 str. 2009EL-2050 13688780 YP_006769968.1 CDS O3M_11615 NC_018650.1 2380816 2381154 R hypothetical protein complement(2380816..2381154) Escherichia coli O104:H4 str. 2009EL-2050 13688781 YP_006769969.1 CDS O3M_11620 NC_018650.1 2381169 2381447 R DNA-binding protein complement(2381169..2381447) Escherichia coli O104:H4 str. 2009EL-2050 13688782 YP_006769970.1 CDS O3M_11625 NC_018650.1 2381539 2381850 D COG2944 Predicted transcriptional regulator; repressor protein C 2381539..2381850 Escherichia coli O104:H4 str. 2009EL-2050 13688783 YP_006769971.1 CDS O3M_11630 NC_018650.1 2381939 2382874 D COG0582 Integrase; integrase 2381939..2382874 Escherichia coli O104:H4 str. 2009EL-2050 13688784 YP_006769972.1 CDS O3M_11635 NC_018650.1 2382885 2383280 D hypothetical protein 2382885..2383280 Escherichia coli O104:H4 str. 2009EL-2050 13688785 YP_006769973.1 CDS O3M_11640 NC_018650.1 2383470 2384450 D COG4139 ABC-type cobalamin transport system, permease component; vtamin B12-transporter permease 2383470..2384450 Escherichia coli O104:H4 str. 2009EL-2050 13688786 YP_006769974.1 CDS btuE NC_018650.1 2384513 2385064 D COG0386 Glutathione peroxidase; glutathione peroxidase 2384513..2385064 Escherichia coli O104:H4 str. 2009EL-2050 13688787 YP_006769975.1 CDS O3M_11650 NC_018650.1 2385064 2385813 D COG4138 ABC-type cobalamin transport system, ATPase component; vitamin B12-transporter ATPase 2385064..2385813 Escherichia coli O104:H4 str. 2009EL-2050 13688788 YP_006769976.1 CDS O3M_11655 NC_018650.1 2385891 2386355 D COG0791 Cell wall-associated hydrolases (invasion-associated proteins); lipoprotein 2385891..2386355 Escherichia coli O104:H4 str. 2009EL-2050 13688789 YP_006769977.1 CDS O3M_11660 NC_018650.1 2386602 2387315 D COG2200 FOG: EAL domain; hypothetical protein 2386602..2387315 Escherichia coli O104:H4 str. 2009EL-2050 13688790 YP_006769978.1 CDS O3M_11665 NC_018650.1 2387378 2388814 D COG0397 Uncharacterized conserved protein; hypothetical protein 2387378..2388814 Escherichia coli O104:H4 str. 2009EL-2050 13688791 YP_006769979.1 CDS O3M_11670 NC_018650.1 2388818 2389009 R COG4256 Hemin uptake protein; hypothetical protein complement(2388818..2389009) Escherichia coli O104:H4 str. 2009EL-2050 13688792 YP_006769980.1 CDS O3M_11675 NC_018650.1 2389141 2390187 R COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2389141..2390187) Escherichia coli O104:H4 str. 2009EL-2050 13688793 YP_006769981.1 CDS O3M_11680 NC_018650.1 2390344 2391177 R COG1806 Uncharacterized protein conserved in bacteria; PEP synthetase regulatory protein complement(2390344..2391177) Escherichia coli O104:H4 str. 2009EL-2050 13688794 YP_006769982.1 CDS O3M_11685 NC_018650.1 2391510 2393888 D COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; phosphoenolpyruvate synthase 2391510..2393888 Escherichia coli O104:H4 str. 2009EL-2050 13688795 YP_006769983.1 CDS O3M_11690 NC_018650.1 2393945 2395645 R COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; short chain acyl-CoA synthetase complement(2393945..2395645) Escherichia coli O104:H4 str. 2009EL-2050 13688796 YP_006769984.1 CDS O3M_11695 NC_018650.1 2395648 2395941 R COG2440 Ferredoxin-like protein; ferredoxin-like protein FixX complement(2395648..2395941) Escherichia coli O104:H4 str. 2009EL-2050 13688797 YP_006769985.1 CDS O3M_11700 NC_018650.1 2395938 2397227 R COG0644 Dehydrogenases (flavoproteins); oxidoreductase complement(2395938..2397227) Escherichia coli O104:H4 str. 2009EL-2050 13688798 YP_006769986.1 CDS O3M_11705 NC_018650.1 2397283 2398221 R COG2025 Electron transfer flavoprotein, alpha subunit; electron transfer flavoprotein subunit YdiR complement(2397283..2398221) Escherichia coli O104:H4 str. 2009EL-2050 13688799 YP_006769987.1 CDS O3M_11710 NC_018650.1 2398241 2399005 R COG2086 Electron transfer flavoprotein, beta subunit; hypothetical protein complement(2398241..2399005) Escherichia coli O104:H4 str. 2009EL-2050 13688800 YP_006769988.1 CDS O3M_11715 NC_018650.1 2399042 2399218 D hypothetical protein 2399042..2399218 Escherichia coli O104:H4 str. 2009EL-2050 13688801 YP_006769989.1 CDS O3M_11720 NC_018650.1 2399321 2400232 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 2399321..2400232 Escherichia coli O104:H4 str. 2009EL-2050 13688802 YP_006769990.1 CDS O3M_11725 NC_018650.1 2400275 2401426 R COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase complement(2400275..2401426) Escherichia coli O104:H4 str. 2009EL-2050 13688803 YP_006769991.1 CDS O3M_11730 NC_018650.1 2401440 2403035 R COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; acetyl-CoA: acetoacetyl-CoA transferase subunit alpha/beta complement(2401440..2403035) Escherichia coli O104:H4 str. 2009EL-2050 13688804 YP_006769992.1 CDS aroD NC_018650.1 2403179 2403937 R COG0710 3-dehydroquinate dehydratase; 3-dehydroquinate dehydratase complement(2403179..2403937) Escherichia coli O104:H4 str. 2009EL-2050 13688805 YP_006769993.1 CDS O3M_11740 NC_018650.1 2403968 2404834 R COG0169 Shikimate 5-dehydrogenase; quinate/shikimate dehydrogenase complement(2403968..2404834) Escherichia coli O104:H4 str. 2009EL-2050 13688806 YP_006769994.1 CDS O3M_11745 NC_018650.1 2404846 2406111 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2404846..2406111) Escherichia coli O104:H4 str. 2009EL-2050 13688807 YP_006769995.1 CDS O3M_11750 NC_018650.1 2406338 2407552 R MFS superfamily protein; COG0477 Permeases of the major facilitator superfamily; transporter complement(2406338..2407552) Escherichia coli O104:H4 str. 2009EL-2050 13688808 YP_006769996.1 CDS O3M_11755 NC_018650.1 2407652 2408008 R hypothetical protein complement(2407652..2408008) Escherichia coli O104:H4 str. 2009EL-2050 13688809 YP_006769997.1 CDS O3M_11760 NC_018650.1 2408437 2409549 R COG0628 Predicted permease; inner membrane protein complement(2408437..2409549) Escherichia coli O104:H4 str. 2009EL-2050 13688810 YP_006769998.1 CDS O3M_11765 NC_018650.1 2409938 2412994 D COG0277 FAD/FMN-containing dehydrogenases; FAD-linked oxidoreductase 2409938..2412994 Escherichia coli O104:H4 str. 2009EL-2050 13688811 YP_006769999.1 CDS O3M_11770 NC_018650.1 2412991 2413401 D COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; acyl-CoA esterase 2412991..2413401 Escherichia coli O104:H4 str. 2009EL-2050 13688812 YP_006770000.1 CDS O3M_11775 NC_018650.1 2413420 2413689 D hypothetical protein 2413420..2413689 Escherichia coli O104:H4 str. 2009EL-2050 13688813 YP_006770001.1 CDS sufA NC_018650.1 2414238 2414606 D COG0316 Uncharacterized conserved protein; iron-sulfur cluster assembly scaffold protein 2414238..2414606 Escherichia coli O104:H4 str. 2009EL-2050 13688814 YP_006770002.1 CDS O3M_11785 NC_018650.1 2414615 2416102 D COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; cysteine desulfurase activator complex subunit SufB 2414615..2416102 Escherichia coli O104:H4 str. 2009EL-2050 13688815 YP_006770003.1 CDS sufC NC_018650.1 2416112 2416858 D COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; cysteine desulfurase 2416112..2416858 Escherichia coli O104:H4 str. 2009EL-2050 13688816 YP_006770004.1 CDS O3M_11795 NC_018650.1 2416833 2418104 D COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; cysteine desulfurase activator complex subunit SufD 2416833..2418104 Escherichia coli O104:H4 str. 2009EL-2050 13688817 YP_006770005.1 CDS O3M_11800 NC_018650.1 2418101 2419321 D COG0520 Selenocysteine lyase; bifunctional cysteine desulfurase/selenocysteine lyase 2418101..2419321 Escherichia coli O104:H4 str. 2009EL-2050 13688818 YP_006770006.1 CDS O3M_11805 NC_018650.1 2419334 2419750 D COG2166 SufE protein probably involved in Fe-S center assembly; cysteine desufuration protein SufE 2419334..2419750 Escherichia coli O104:H4 str. 2009EL-2050 13688819 YP_006770007.1 CDS O3M_11810 NC_018650.1 2419899 2420903 D COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 2419899..2420903 Escherichia coli O104:H4 str. 2009EL-2050 13688820 YP_006770008.1 CDS O3M_11815 NC_018650.1 2420967 2421203 R COG4238 Murein lipoprotein; murein lipoprotein complement(2420967..2421203) Escherichia coli O104:H4 str. 2009EL-2050 13688821 YP_006770009.1 CDS O3M_11820 NC_018650.1 2421514 2422926 R COG0469 Pyruvate kinase; pyruvate kinase complement(2421514..2422926) Escherichia coli O104:H4 str. 2009EL-2050 13688822 YP_006770010.1 CDS O3M_11825 NC_018650.1 2423483 2423692 D hypothetical protein 2423483..2423692 Escherichia coli O104:H4 str. 2009EL-2050 13688823 YP_006770011.1 CDS O3M_11830 NC_018650.1 2424148 2424774 D COG0437 Fe-S-cluster-containing hydrogenase components 1; hypothetical protein 2424148..2424774 Escherichia coli O104:H4 str. 2009EL-2050 13688824 YP_006770012.1 CDS O3M_11835 NC_018650.1 2424795 2426897 D COG2414 Aldehyde:ferredoxin oxidoreductase; oxidoreductase 2424795..2426897 Escherichia coli O104:H4 str. 2009EL-2050 13688825 YP_006770013.1 CDS O3M_11840 NC_018650.1 2426901 2427548 D hypothetical protein 2426901..2427548 Escherichia coli O104:H4 str. 2009EL-2050 13688826 YP_006770014.1 CDS O3M_11845 NC_018650.1 2427561 2428280 D COG0437 Fe-S-cluster-containing hydrogenase components 1; oxidoreductase, Fe-S subunit 2427561..2428280 Escherichia coli O104:H4 str. 2009EL-2050 13688827 YP_006770015.1 CDS O3M_11850 NC_018650.1 2428277 2429062 D thiosulfate reductase cytochrome B subunit 2428277..2429062 Escherichia coli O104:H4 str. 2009EL-2050 13688828 YP_006770016.1 CDS O3M_11855 NC_018650.1 2429066 2429878 D hypothetical protein 2429066..2429878 Escherichia coli O104:H4 str. 2009EL-2050 13688829 YP_006770017.1 CDS O3M_11860 NC_018650.1 2429890 2431494 R COG4529 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2429890..2431494) Escherichia coli O104:H4 str. 2009EL-2050 13688830 YP_006770018.1 CDS O3M_11865 NC_018650.1 2431620 2431925 R COG0113 Delta-aminolevulinic acid dehydratase; monooxygenase complement(2431620..2431925) Escherichia coli O104:H4 str. 2009EL-2050 13688831 YP_006770019.1 CDS O3M_11870 NC_018650.1 2432498 2433754 D hypothetical protein 2432498..2433754 Escherichia coli O104:H4 str. 2009EL-2050 13688834 YP_006770020.1 CDS O3M_11875 NC_018650.1 2433795 2435168 R COG0534 Na+-driven multidrug efflux pump; multidrug efflux protein complement(2433795..2435168) Escherichia coli O104:H4 str. 2009EL-2050 13688835 YP_006770021.1 CDS O3M_11880 NC_018650.1 2435383 2436024 D COG0307 Riboflavin synthase alpha chain; riboflavin synthase subunit alpha 2435383..2436024 Escherichia coli O104:H4 str. 2009EL-2050 13688836 YP_006770022.1 CDS O3M_11885 NC_018650.1 2436064 2437212 R COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane-fatty-acyl-phospholipid synthase complement(2436064..2437212) Escherichia coli O104:H4 str. 2009EL-2050 13688837 YP_006770023.1 CDS O3M_11890 NC_018650.1 2437503 2438714 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2437503..2438714) Escherichia coli O104:H4 str. 2009EL-2050 13688838 YP_006770024.1 CDS O3M_11895 NC_018650.1 2438827 2439759 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 2438827..2439759 Escherichia coli O104:H4 str. 2009EL-2050 13688839 YP_006770025.1 CDS O3M_11900 NC_018650.1 2439756 2440781 R COG1609 Transcriptional regulators; DNA-binding transcriptional repressor PurR complement(2439756..2440781) Escherichia coli O104:H4 str. 2009EL-2050 13688840 YP_006770026.1 CDS O3M_11905 NC_018650.1 2441080 2441169 D hypothetical protein 2441080..2441169 Escherichia coli O104:H4 str. 2009EL-2050 13688841 YP_006770027.1 CDS O3M_11910 NC_018650.1 2441335 2442504 D COG2814 Arabinose efflux permease; transporter 2441335..2442504 Escherichia coli O104:H4 str. 2009EL-2050 13688842 YP_006770028.1 CDS O3M_11915 NC_018650.1 2442650 2443231 R COG0605 Superoxide dismutase; superoxide dismutase complement(2442650..2443231) Escherichia coli O104:H4 str. 2009EL-2050 13688843 YP_006770029.1 CDS O3M_11920 NC_018650.1 2443359 2444174 R COG0791 Cell wall-associated hydrolases (invasion-associated proteins); lipoprotein complement(2443359..2444174) Escherichia coli O104:H4 str. 2009EL-2050 13688844 YP_006770030.1 CDS O3M_11925 NC_018650.1 2444508 2444855 D COG0278 Glutaredoxin-related protein; glutaredoxin-4 2444508..2444855 Escherichia coli O104:H4 str. 2009EL-2050 13688845 YP_006770031.1 CDS O3M_11930 NC_018650.1 2444906 2449522 R COG1201 Lhr-like helicases; ATP-dependent helicase Lhr complement(2444906..2449522) Escherichia coli O104:H4 str. 2009EL-2050 13688846 YP_006770032.1 CDS O3M_11935 NC_018650.1 2449615 2450262 R COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; ribonuclease T complement(2449615..2450262) Escherichia coli O104:H4 str. 2009EL-2050 13688847 YP_006770033.1 CDS O3M_11940 NC_018650.1 2450365 2450772 R COG0346 Lactoylglutathione lyase and related lyases; glyoxalase I complement(2450365..2450772) Escherichia coli O104:H4 str. 2009EL-2050 13688848 YP_006770034.1 CDS O3M_11945 NC_018650.1 2450853 2451950 R COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; N-ethylmaleimide reductase complement(2450853..2451950) Escherichia coli O104:H4 str. 2009EL-2050 13688849 YP_006770035.1 CDS O3M_11950 NC_018650.1 2451987 2452586 R COG1309 Transcriptional regulator; DNA-binding transcriptional regulator complement(2451987..2452586) Escherichia coli O104:H4 str. 2009EL-2050 13688850 YP_006770036.1 CDS O3M_11955 NC_018650.1 2452518 2452928 D COG3313 Predicted Fe-S protein; hypothetical protein 2452518..2452928 Escherichia coli O104:H4 str. 2009EL-2050 13688851 YP_006770037.1 CDS O3M_11960 NC_018650.1 2452977 2453873 D COG4989 Predicted oxidoreductase; oxidoreductase 2452977..2453873 Escherichia coli O104:H4 str. 2009EL-2050 13688852 YP_006770038.1 CDS O3M_11965 NC_018650.1 2453954 2454475 D COG2032 Cu/Zn superoxide dismutase; superoxide dismutase 2453954..2454475 Escherichia coli O104:H4 str. 2009EL-2050 13688853 YP_006770039.1 CDS O3M_11970 NC_018650.1 2454476 2456488 R COG1289 Predicted membrane protein; hypothetical protein complement(2454476..2456488) Escherichia coli O104:H4 str. 2009EL-2050 13688854 YP_006770040.1 CDS O3M_11975 NC_018650.1 2456488 2457345 R COG1566 Multidrug resistance efflux pump; undecaprenyl pyrophosphate phosphatase complement(2456488..2457345) Escherichia coli O104:H4 str. 2009EL-2050 13688855 YP_006770041.1 CDS O3M_11980 NC_018650.1 2457348 2457584 R hypothetical protein complement(2457348..2457584) Escherichia coli O104:H4 str. 2009EL-2050 13688856 YP_006770042.1 CDS O3M_11985 NC_018650.1 2457785 2458219 D COG1846 Transcriptional regulators; transcriptional regulator SlyA 2457785..2458219 Escherichia coli O104:H4 str. 2009EL-2050 13688857 YP_006770043.1 CDS O3M_11990 NC_018650.1 2458266 2458733 R COG3133 Outer membrane lipoprotein; outer membrane lipoprotein SlyB complement(2458266..2458733) Escherichia coli O104:H4 str. 2009EL-2050 13688858 YP_006770044.1 CDS anmK NC_018650.1 2459007 2460116 D COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases; anhydro-N-acetylmuramic acid kinase 2459007..2460116 Escherichia coli O104:H4 str. 2009EL-2050 13688859 YP_006770045.1 CDS O3M_12000 NC_018650.1 2460214 2460543 D COG3895 Predicted periplasmic protein; lysozyme inhibitor 2460214..2460543 Escherichia coli O104:H4 str. 2009EL-2050 13688860 YP_006770046.1 CDS O3M_12005 NC_018650.1 2460602 2461258 D COG0259 Pyridoxamine-phosphate oxidase; pyridoxamine 5'-phosphate oxidase 2460602..2461258 Escherichia coli O104:H4 str. 2009EL-2050 13688861 YP_006770047.1 CDS O3M_12010 NC_018650.1 2461387 2462661 D COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 2461387..2462661 Escherichia coli O104:H4 str. 2009EL-2050 13688862 YP_006770048.1 CDS O3M_12015 NC_018650.1 2462723 2463583 D COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxamine kinase 2462723..2463583 Escherichia coli O104:H4 str. 2009EL-2050 13688863 YP_006770049.1 CDS O3M_12020 NC_018650.1 2463627 2464232 R COG0625 Glutathione S-transferase; glutathionine S-transferase complement(2463627..2464232) Escherichia coli O104:H4 str. 2009EL-2050 13688864 YP_006770050.1 CDS tppB NC_018650.1 2464338 2465840 R COG3104 Dipeptide/tripeptide permease; tripeptide transporter permease complement(2464338..2465840) Escherichia coli O104:H4 str. 2009EL-2050 13688865 YP_006770051.1 CDS O3M_12030 NC_018650.1 2466123 2466323 R hypothetical protein complement(2466123..2466323) Escherichia coli O104:H4 str. 2009EL-2050 13688866 YP_006770052.1 CDS O3M_12035 NC_018650.1 2466451 2467086 R COG0177 Predicted EndoIII-related endonuclease; endonuclease III complement(2466451..2467086) Escherichia coli O104:H4 str. 2009EL-2050 13688867 YP_006770053.1 CDS O3M_12040 NC_018650.1 2467086 2467781 R COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE; electron transport complex protein RsxE complement(2467086..2467781) Escherichia coli O104:H4 str. 2009EL-2050 13688868 YP_006770054.1 CDS O3M_12045 NC_018650.1 2467785 2468405 R COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG; electron transport complex protein RnfG complement(2467785..2468405) Escherichia coli O104:H4 str. 2009EL-2050 13688869 YP_006770055.1 CDS rnfD NC_018650.1 2468409 2469467 R COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD; electron transport complex protein RnfD complement(2468409..2469467) Escherichia coli O104:H4 str. 2009EL-2050 13688870 YP_006770056.1 CDS O3M_12055 NC_018650.1 2469468 2471594 R COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC; electron transport complex protein RnfC complement(2469468..2471594) Escherichia coli O104:H4 str. 2009EL-2050 13688871 YP_006770057.1 CDS O3M_12060 NC_018650.1 2471587 2472165 R COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB; electron transport complex protein RnfB complement(2471587..2472165) Escherichia coli O104:H4 str. 2009EL-2050 13688872 YP_006770058.1 CDS O3M_12065 NC_018650.1 2472165 2472746 R COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA; electron transport complex protein RsxA complement(2472165..2472746) Escherichia coli O104:H4 str. 2009EL-2050 13688873 YP_006770059.1 CDS O3M_12070 NC_018650.1 2472823 2473263 R hypothetical protein complement(2472823..2473263) Escherichia coli O104:H4 str. 2009EL-2050 13688874 YP_006770060.1 CDS O3M_12075 NC_018650.1 2473349 2473564 R oriC-binding nucleoid-associated protein complement(2473349..2473564) Escherichia coli O104:H4 str. 2009EL-2050 13688875 YP_006770061.1 CDS O3M_12080 NC_018650.1 2474205 2475245 D COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 2474205..2475245 Escherichia coli O104:H4 str. 2009EL-2050 13688876 YP_006770062.1 CDS O3M_12085 NC_018650.1 2475280 2476281 R COG1816 Adenosine deaminase; adenosine deaminase complement(2475280..2476281) Escherichia coli O104:H4 str. 2009EL-2050 13688877 YP_006770063.1 CDS O3M_12090 NC_018650.1 2476385 2477557 R COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; bifunctional beta-cystathionase and regulator of maltose regulon complement(2476385..2477557) Escherichia coli O104:H4 str. 2009EL-2050 13688878 YP_006770064.1 CDS O3M_12095 NC_018650.1 2477567 2479159 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system maltose and glucose-specific transporter subunits IICB complement(2477567..2479159) Escherichia coli O104:H4 str. 2009EL-2050 13688879 YP_006770065.1 CDS O3M_12100 NC_018650.1 2479334 2480362 D COG1609 Transcriptional regulators; DNA-binding transcriptional repressor MalI 2479334..2480362 Escherichia coli O104:H4 str. 2009EL-2050 13688880 YP_006770066.1 CDS O3M_12105 NC_018650.1 2480474 2481241 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 7-alpha-hydroxysteroid dehydrogenase 2480474..2481241 Escherichia coli O104:H4 str. 2009EL-2050 13688881 YP_006770067.1 CDS O3M_12110 NC_018650.1 2481470 2482060 D COG1309 Transcriptional regulator; DNA-binding transcriptional repressor UidR 2481470..2482060 Escherichia coli O104:H4 str. 2009EL-2050 13688882 YP_006770068.1 CDS O3M_12115 NC_018650.1 2482449 2484260 D COG3250 Beta-galactosidase/beta-glucuronidase; beta-D-glucuronidase 2482449..2484260 Escherichia coli O104:H4 str. 2009EL-2050 13688883 YP_006770069.1 CDS O3M_12120 NC_018650.1 2484257 2485630 D COG2211 Na+/melibiose symporter and related transporters; glucuronide transporter 2484257..2485630 Escherichia coli O104:H4 str. 2009EL-2050 13688884 YP_006770070.1 CDS O3M_12125 NC_018650.1 2485669 2486934 D outer membrane porin protein 2485669..2486934 Escherichia coli O104:H4 str. 2009EL-2050 13688885 YP_006770071.1 CDS O3M_12130 NC_018650.1 2486979 2488487 R COG5339 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2486979..2488487) Escherichia coli O104:H4 str. 2009EL-2050 13688886 YP_006770072.1 CDS O3M_12135 NC_018650.1 2488588 2489763 R COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase complement(2488588..2489763) Escherichia coli O104:H4 str. 2009EL-2050 13688887 YP_006770073.1 CDS O3M_12140 NC_018650.1 2489962 2491608 D COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase FumA 2489962..2491608 Escherichia coli O104:H4 str. 2009EL-2050 13688888 YP_006770074.1 CDS fumC NC_018650.1 2491751 2493154 D COG0114 Fumarase; fumarate hydratase 2491751..2493154 Escherichia coli O104:H4 str. 2009EL-2050 13688889 YP_006770075.1 CDS O3M_12150 NC_018650.1 2493151 2494080 R DNA replication terminus site-binding protein complement(2493151..2494080) Escherichia coli O104:H4 str. 2009EL-2050 13688890 YP_006770076.1 CDS O3M_12155 NC_018650.1 2494156 2495457 R COG0642 Signal transduction histidine kinase; sensor protein RstB complement(2494156..2495457) Escherichia coli O104:H4 str. 2009EL-2050 13688891 YP_006770077.1 CDS O3M_12160 NC_018650.1 2495461 2496180 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator RstA complement(2495461..2496180) Escherichia coli O104:H4 str. 2009EL-2050 13688892 YP_006770078.1 CDS O3M_12165 NC_018650.1 2496309 2496644 D COG3136 Uncharacterized membrane protein required for alginate biosynthesis; GlpM family protein 2496309..2496644 Escherichia coli O104:H4 str. 2009EL-2050 13688893 YP_006770079.1 CDS O3M_12170 NC_018650.1 2496641 2497363 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dihydromonapterin reductase complement(2496641..2497363) Escherichia coli O104:H4 str. 2009EL-2050 13688894 YP_006770080.1 CDS O3M_12175 NC_018650.1 2497400 2498782 R COG0531 Amino acid transporters; arginine/ornithine antiporter complement(2497400..2498782) Escherichia coli O104:H4 str. 2009EL-2050 13688895 YP_006770081.1 CDS O3M_12180 NC_018650.1 2498968 2499912 R hypothetical protein complement(2498968..2499912) Escherichia coli O104:H4 str. 2009EL-2050 13688896 YP_006770082.1 CDS pntA NC_018650.1 2500436 2501968 D COG3288 NAD/NADP transhydrogenase alpha subunit; NAD(P) transhydrogenase subunit alpha 2500436..2501968 Escherichia coli O104:H4 str. 2009EL-2050 13688897 YP_006770083.1 CDS pntB NC_018650.1 2501979 2503367 D COG1282 NAD/NADP transhydrogenase beta subunit; pyridine nucleotide transhydrogenase 2501979..2503367 Escherichia coli O104:H4 str. 2009EL-2050 13688898 YP_006770084.1 CDS tqsA NC_018650.1 2503392 2504426 R COG0628 Predicted permease; pheromone autoinducer 2 transporter complement(2503392..2504426) Escherichia coli O104:H4 str. 2009EL-2050 13688899 YP_006770085.1 CDS O3M_12200 NC_018650.1 2504838 2505203 D COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux system protein MdtJ 2504838..2505203 Escherichia coli O104:H4 str. 2009EL-2050 13688900 YP_006770086.1 CDS O3M_12205 NC_018650.1 2505190 2505519 D COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux system protein MdtI 2505190..2505519 Escherichia coli O104:H4 str. 2009EL-2050 13688901 YP_006770087.1 CDS O3M_12210 NC_018650.1 2505558 2506379 R COG3591 V8-like Glu-specific endopeptidase; metallopeptidase complement(2505558..2506379) Escherichia coli O104:H4 str. 2009EL-2050 13688902 YP_006770088.1 CDS O3M_12215 NC_018650.1 2506479 2506562 R hypothetical protein complement(2506479..2506562) Escherichia coli O104:H4 str. 2009EL-2050 13688903 YP_006770089.1 CDS O3M_12220 NC_018650.1 2506655 2506963 R acid shock protein complement(2506655..2506963) Escherichia coli O104:H4 str. 2009EL-2050 13688904 YP_006770090.1 CDS O3M_12225 NC_018650.1 2507387 2508640 R MFS type; COG0477 Permeases of the major facilitator superfamily; transporter complement(2507387..2508640) Escherichia coli O104:H4 str. 2009EL-2050 13688905 YP_006770091.1 CDS O3M_12230 NC_018650.1 2508747 2509640 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 2508747..2509640 Escherichia coli O104:H4 str. 2009EL-2050 13688906 YP_006770092.1 CDS O3M_12235 NC_018650.1 2509775 2510995 D COG1940 Transcriptional regulator/sugar kinase; NAGC-like transcriptional regulator 2509775..2510995 Escherichia coli O104:H4 str. 2009EL-2050 13688907 YP_006770093.1 CDS O3M_12240 NC_018650.1 2511120 2511815 D COG0132 Dethiobiotin synthetase; dithiobiotin synthetase 2511120..2511815 Escherichia coli O104:H4 str. 2009EL-2050 13688908 YP_006770094.1 CDS O3M_12245 NC_018650.1 2511831 2513024 R COG0038 Chloride channel protein EriC; voltage-gated ClC-type chloride channel ClcB complement(2511831..2513024) Escherichia coli O104:H4 str. 2009EL-2050 13688909 YP_006770095.1 CDS O3M_12250 NC_018650.1 2513219 2513833 R COG3381 Uncharacterized component of anaerobic dehydrogenases; twin-argninine leader-binding protein DmsD complement(2513219..2513833) Escherichia coli O104:H4 str. 2009EL-2050 13688910 YP_006770096.1 CDS O3M_12255 NC_018650.1 2513876 2514730 R COG3302 DMSO reductase anchor subunit; oxidoreductase, membrane subunit complement(2513876..2514730) Escherichia coli O104:H4 str. 2009EL-2050 13688911 YP_006770097.1 CDS O3M_12260 NC_018650.1 2514732 2515283 R COG0437 Fe-S-cluster-containing hydrogenase components 1; anaerobic dimethyl sulfoxide reductase subunit ynfG complement(2514732..2515283) Escherichia coli O104:H4 str. 2009EL-2050 13688912 YP_006770098.1 CDS O3M_12265 NC_018650.1 2515324 2516487 R COG0582 Integrase; prophage DLP12 integrase complement(2515324..2516487) Escherichia coli O104:H4 str. 2009EL-2050 13688913 YP_006770099.1 CDS O3M_12270 NC_018650.1 2516343 2516714 R COG2452 Predicted site-specific integrase-resolvase; excisionase complement(2516343..2516714) Escherichia coli O104:H4 str. 2009EL-2050 13688914 YP_006770100.1 CDS O3M_12275 NC_018650.1 2516749 2517000 R hypothetical protein complement(2516749..2517000) Escherichia coli O104:H4 str. 2009EL-2050 13688915 YP_006770101.1 CDS O3M_12280 NC_018650.1 2517048 2517728 R exonuclease complement(2517048..2517728) Escherichia coli O104:H4 str. 2009EL-2050 13688916 YP_006770102.1 CDS O3M_12285 NC_018650.1 2517725 2518510 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Recombination protein bet from phage origin complement(2517725..2518510) Escherichia coli O104:H4 str. 2009EL-2050 13688917 YP_006770103.1 CDS O3M_12290 NC_018650.1 2518516 2518812 R host-nuclease inhibitor protein Gam of bacteriophage complement(2518516..2518812) Escherichia coli O104:H4 str. 2009EL-2050 13688918 YP_006770104.1 CDS O3M_12300 NC_018650.1 2520989 2521375 R hypothetical protein complement(2520989..2521375) Escherichia coli O104:H4 str. 2009EL-2050 13688919 YP_006770105.1 CDS kil NC_018650.1 2521459 2521680 R FtsZ inhibitor protein complement(2521459..2521680) Escherichia coli O104:H4 str. 2009EL-2050 13688920 YP_006770106.1 CDS O3M_12310 NC_018650.1 2522137 2522346 D hypothetical protein 2522137..2522346 Escherichia coli O104:H4 str. 2009EL-2050 13688921 YP_006770107.1 CDS O3M_12315 NC_018650.1 2522315 2522674 R hypothetical protein complement(2522315..2522674) Escherichia coli O104:H4 str. 2009EL-2050 13688922 YP_006770108.1 CDS O3M_12320 NC_018650.1 2522706 2523419 R hypothetical protein complement(2522706..2523419) Escherichia coli O104:H4 str. 2009EL-2050 13688923 YP_006770109.1 CDS O3M_12325 NC_018650.1 2523423 2523806 R Antitermination protein N complement(2523423..2523806) Escherichia coli O104:H4 str. 2009EL-2050 13688924 YP_006770110.1 CDS O3M_12330 NC_018650.1 2524301 2525077 R hypothetical protein complement(2524301..2525077) Escherichia coli O104:H4 str. 2009EL-2050 13688925 YP_006770111.1 CDS O3M_12335 NC_018650.1 2525065 2525607 R hypothetical protein complement(2525065..2525607) Escherichia coli O104:H4 str. 2009EL-2050 13688926 YP_006770112.1 CDS O3M_12340 NC_018650.1 2525654 2526367 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Repressor protein CI from prophage complement(2525654..2526367) Escherichia coli O104:H4 str. 2009EL-2050 13688927 YP_006770113.1 CDS O3M_12345 NC_018650.1 2526468 2526668 D regulatory protein cro 2526468..2526668 Escherichia coli O104:H4 str. 2009EL-2050 13688928 YP_006770114.1 CDS O3M_12350 NC_018650.1 2526807 2527103 D regulatory protein CII from prophage 2526807..2527103 Escherichia coli O104:H4 str. 2009EL-2050 13688929 YP_006770115.1 CDS O3M_12355 NC_018650.1 2527118 2527336 D hypothetical protein 2527118..2527336 Escherichia coli O104:H4 str. 2009EL-2050 13688930 YP_006770116.1 CDS O3M_12360 NC_018650.1 2527438 2528439 D hypothetical protein 2527438..2528439 Escherichia coli O104:H4 str. 2009EL-2050 13688931 YP_006770117.1 CDS O3M_12365 NC_018650.1 2528446 2529186 D COG1484 DNA replication protein; replication protein 2528446..2529186 Escherichia coli O104:H4 str. 2009EL-2050 13688932 YP_006770118.1 CDS O3M_12370 NC_018650.1 2529212 2529982 D COG1349 Transcriptional regulators of sugar metabolism; hypothetical protein 2529212..2529982 Escherichia coli O104:H4 str. 2009EL-2050 13688933 YP_006770119.1 CDS O3M_12375 NC_018650.1 2529998 2530393 D hypothetical protein 2529998..2530393 Escherichia coli O104:H4 str. 2009EL-2050 13688934 YP_006770120.1 CDS O3M_12380 NC_018650.1 2530450 2531034 D hypothetical protein 2530450..2531034 Escherichia coli O104:H4 str. 2009EL-2050 13688935 YP_006770121.1 CDS O3M_12385 NC_018650.1 2531150 2531254 D hypothetical protein 2531150..2531254 Escherichia coli O104:H4 str. 2009EL-2050 13688936 YP_006770122.1 CDS O3M_12390 NC_018650.1 2531443 2531655 D cell killing protein encoded within cryptic prophage CP-933P 2531443..2531655 Escherichia coli O104:H4 str. 2009EL-2050 13688937 YP_006770123.1 CDS O3M_12395 NC_018650.1 2531865 2532044 D bacteriophage protein 2531865..2532044 Escherichia coli O104:H4 str. 2009EL-2050 13688938 YP_006770124.1 CDS O3M_12400 NC_018650.1 2532063 2532548 D COG3654 Prophage maintenance system killer protein; bacteriophage protein 2532063..2532548 Escherichia coli O104:H4 str. 2009EL-2050 13688939 YP_006770125.1 CDS O3M_12405 NC_018650.1 2532599 2532916 R COG2944 Predicted transcriptional regulator; DNA-binding protein complement(2532599..2532916) Escherichia coli O104:H4 str. 2009EL-2050 13688940 YP_006770126.1 CDS O3M_12410 NC_018650.1 2533024 2533278 R COG4737 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2533024..2533278) Escherichia coli O104:H4 str. 2009EL-2050 13688941 YP_006770127.1 CDS O3M_12415 NC_018650.1 2533623 2534294 D antirepressor protein Ant from prophage 2533623..2534294 Escherichia coli O104:H4 str. 2009EL-2050 13688942 YP_006770128.1 CDS O3M_12420 NC_018650.1 2534349 2534759 D ninB protein 2534349..2534759 Escherichia coli O104:H4 str. 2009EL-2050 13688943 YP_006770129.1 CDS O3M_12425 NC_018650.1 2534756 2534947 D NinE protein 2534756..2534947 Escherichia coli O104:H4 str. 2009EL-2050 13688944 YP_006770130.1 CDS O3M_12430 NC_018650.1 2534971 2535261 D hypothetical protein 2534971..2535261 Escherichia coli O104:H4 str. 2009EL-2050 13688945 YP_006770131.1 CDS O3M_12435 NC_018650.1 2535258 2535620 D COG4570 Holliday junction resolvase; crossover junction endodeoxyribonuclease 2535258..2535620 Escherichia coli O104:H4 str. 2009EL-2050 13688946 YP_006770132.1 CDS O3M_12440 NC_018650.1 2535620 2535814 D Protein ninH from prophage 2535620..2535814 Escherichia coli O104:H4 str. 2009EL-2050 13688947 YP_006770133.1 CDS O3M_12445 NC_018650.1 2535807 2536241 D antitermination protein Q 2535807..2536241 Escherichia coli O104:H4 str. 2009EL-2050 13688948 YP_006770134.1 CDS O3M_12450 NC_018650.1 2537007 2538917 D hypothetical protein 2537007..2538917 Escherichia coli O104:H4 str. 2009EL-2050 13688949 YP_006770135.1 CDS O3M_12455 NC_018650.1 2539056 2539238 D hypothetical protein 2539056..2539238 Escherichia coli O104:H4 str. 2009EL-2050 13688950 YP_006770136.1 CDS O3M_12460 NC_018650.1 2539264 2539509 D hypothetical protein 2539264..2539509 Escherichia coli O104:H4 str. 2009EL-2050 13688951 YP_006770137.1 CDS O3M_12465 NC_018650.1 2539586 2539801 D lysis protein S of prophage CP-933V 2539586..2539801 Escherichia coli O104:H4 str. 2009EL-2050 13688952 YP_006770138.1 CDS O3M_12470 NC_018650.1 2539806 2540339 D COG3772 Phage-related lysozyme (muraminidase); endolysin 2539806..2540339 Escherichia coli O104:H4 str. 2009EL-2050 13688953 YP_006770139.1 CDS O3M_12475 NC_018650.1 2540560 2540673 D hypothetical protein 2540560..2540673 Escherichia coli O104:H4 str. 2009EL-2050 13688954 YP_006770140.1 CDS O3M_12480 NC_018650.1 2540675 2541133 D endopeptidase 2540675..2541133 Escherichia coli O104:H4 str. 2009EL-2050 13688955 YP_006770141.1 CDS O3M_12485 NC_018650.1 2541214 2541795 R lipopolysaccharide core heptose(II)-phosphate phosphatase complement(2541214..2541795) Escherichia coli O104:H4 str. 2009EL-2050 13688956 YP_006770142.1 CDS O3M_12490 NC_018650.1 2542398 2543213 D small subunit terminase 2542398..2543213 Escherichia coli O104:H4 str. 2009EL-2050 13688957 YP_006770143.1 CDS O3M_12495 NC_018650.1 2543194 2544900 D large subunit terminase 2543194..2544900 Escherichia coli O104:H4 str. 2009EL-2050 13688958 YP_006770144.1 CDS O3M_12500 NC_018650.1 2544900 2547044 D portal protein 2544900..2547044 Escherichia coli O104:H4 str. 2009EL-2050 13688959 YP_006770145.1 CDS O3M_12505 NC_018650.1 2547202 2548209 D COG0061 Predicted sugar kinase; hypothetical protein 2547202..2548209 Escherichia coli O104:H4 str. 2009EL-2050 13688960 YP_006770146.1 CDS O3M_12510 NC_018650.1 2548232 2549446 D hypothetical protein 2548232..2549446 Escherichia coli O104:H4 str. 2009EL-2050 13688961 YP_006770147.1 CDS O3M_12515 NC_018650.1 2549501 2549890 D hypothetical protein 2549501..2549890 Escherichia coli O104:H4 str. 2009EL-2050 13688962 YP_006770148.1 CDS O3M_12520 NC_018650.1 2549941 2550402 D hypothetical protein 2549941..2550402 Escherichia coli O104:H4 str. 2009EL-2050 13688963 YP_006770149.1 CDS O3M_12525 NC_018650.1 2550386 2550949 D hypothetical protein 2550386..2550949 Escherichia coli O104:H4 str. 2009EL-2050 13688964 YP_006770150.1 CDS O3M_12530 NC_018650.1 2550949 2551599 D hypothetical protein 2550949..2551599 Escherichia coli O104:H4 str. 2009EL-2050 13688965 YP_006770151.1 CDS O3M_12535 NC_018650.1 2551596 2553503 D tail fiber protein 2551596..2553503 Escherichia coli O104:H4 str. 2009EL-2050 13688966 YP_006770152.1 CDS O3M_12540 NC_018650.1 2554712 2556337 D hypothetical protein 2554712..2556337 Escherichia coli O104:H4 str. 2009EL-2050 13688967 YP_006770153.1 CDS O3M_12545 NC_018650.1 2556334 2557602 D COG4733 Phage-related protein, tail component; tail tip fiber protein 2556334..2557602 Escherichia coli O104:H4 str. 2009EL-2050 13688968 YP_006770154.1 CDS O3M_12550 NC_018650.1 2557617 2557895 D outer membrane protein 2557617..2557895 Escherichia coli O104:H4 str. 2009EL-2050 13688969 YP_006770155.1 CDS O3M_12555 NC_018650.1 2557901 2558518 D hypothetical protein 2557901..2558518 Escherichia coli O104:H4 str. 2009EL-2050 13688970 YP_006770156.1 CDS O3M_12560 NC_018650.1 2558598 2559335 D outer membrane precursor Lom 2558598..2559335 Escherichia coli O104:H4 str. 2009EL-2050 13688971 YP_006770157.1 CDS O3M_12565 NC_018650.1 2559570 2559710 D hypothetical protein 2559570..2559710 Escherichia coli O104:H4 str. 2009EL-2050 13688972 YP_006770158.1 CDS O3M_12570 NC_018650.1 2559767 2560168 D hypothetical protein 2559767..2560168 Escherichia coli O104:H4 str. 2009EL-2050 13688973 YP_006770159.1 CDS O3M_12575 NC_018650.1 2560260 2560916 D hypothetical protein 2560260..2560916 Escherichia coli O104:H4 str. 2009EL-2050 13688974 YP_006770160.1 CDS O3M_12580 NC_018650.1 2560919 2561365 D hypothetical protein 2560919..2561365 Escherichia coli O104:H4 str. 2009EL-2050 13688975 YP_006770161.1 CDS O3M_12585 NC_018650.1 2561375 2561626 D hypothetical protein 2561375..2561626 Escherichia coli O104:H4 str. 2009EL-2050 13688976 YP_006770162.1 CDS O3M_12590 NC_018650.1 2561637 2562902 D hypothetical protein 2561637..2562902 Escherichia coli O104:H4 str. 2009EL-2050 13688977 YP_006770163.1 CDS O3M_12595 NC_018650.1 2562971 2571322 D COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); hypothetical protein 2562971..2571322 Escherichia coli O104:H4 str. 2009EL-2050 13688978 YP_006770164.1 CDS O3M_12600 NC_018650.1 2571446 2571721 D hypothetical protein 2571446..2571721 Escherichia coli O104:H4 str. 2009EL-2050 13688979 YP_006770165.1 CDS O3M_12605 NC_018650.1 2571723 2572226 R hypothetical protein complement(2571723..2572226) Escherichia coli O104:H4 str. 2009EL-2050 13688980 YP_006770166.1 CDS O3M_12610 NC_018650.1 2572223 2572738 R hypothetical protein complement(2572223..2572738) Escherichia coli O104:H4 str. 2009EL-2050 13688981 YP_006770167.1 CDS O3M_12615 NC_018650.1 2572740 2573576 R hypothetical protein complement(2572740..2573576) Escherichia coli O104:H4 str. 2009EL-2050 13688982 YP_006770168.1 CDS O3M_12620 NC_018650.1 2573563 2573847 R hypothetical protein complement(2573563..2573847) Escherichia coli O104:H4 str. 2009EL-2050 13688983 YP_006770169.1 CDS O3M_12625 NC_018650.1 2573844 2574065 R COG1734 DnaK suppressor protein; C4-type zinc finger protein complement(2573844..2574065) Escherichia coli O104:H4 str. 2009EL-2050 13688984 YP_006770170.1 CDS O3M_12630 NC_018650.1 2574113 2574748 R COG3561 Phage anti-repressor protein; phage anti-repressor protein AntB complement(2574113..2574748) Escherichia coli O104:H4 str. 2009EL-2050 13688985 YP_006770171.1 CDS O3M_12635 NC_018650.1 2575156 2575269 R COG0437 Fe-S-cluster-containing hydrogenase components 1; dimethyl sulfoxide reductase subunit B complement(2575156..2575269) Escherichia coli O104:H4 str. 2009EL-2050 13688986 YP_006770172.1 CDS O3M_12640 NC_018650.1 2575280 2577703 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase subunit complement(2575280..2577703) Escherichia coli O104:H4 str. 2009EL-2050 13688987 YP_006770173.1 CDS O3M_12645 NC_018650.1 2577764 2580190 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase subunit complement(2577764..2580190) Escherichia coli O104:H4 str. 2009EL-2050 13688988 YP_006770174.1 CDS O3M_12650 NC_018650.1 2580389 2580694 R hypothetical protein complement(2580389..2580694) Escherichia coli O104:H4 str. 2009EL-2050 13688989 YP_006770175.1 CDS O3M_12655 NC_018650.1 2580802 2581512 D lipoprotein 2580802..2581512 Escherichia coli O104:H4 str. 2009EL-2050 13688990 YP_006770176.1 CDS O3M_12660 NC_018650.1 2581515 2582075 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; spermidine N1-acetyltransferase complement(2581515..2582075) Escherichia coli O104:H4 str. 2009EL-2050 13688991 YP_006770177.1 CDS O3M_12665 NC_018650.1 2582110 2582451 R hypothetical protein complement(2582110..2582451) Escherichia coli O104:H4 str. 2009EL-2050 13688992 YP_006770178.1 CDS O3M_12670 NC_018650.1 2582586 2582912 D COG1742 Uncharacterized conserved protein; hypothetical protein 2582586..2582912 Escherichia coli O104:H4 str. 2009EL-2050 13688993 YP_006770179.1 CDS O3M_12675 NC_018650.1 2583118 2584332 D COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; bifunctional D-altronate/D-mannonate dehydratase 2583118..2584332 Escherichia coli O104:H4 str. 2009EL-2050 13688994 YP_006770180.1 CDS O3M_12680 NC_018650.1 2584344 2585363 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase 2584344..2585363 Escherichia coli O104:H4 str. 2009EL-2050 13688995 YP_006770181.1 CDS O3M_12685 NC_018650.1 2585505 2586788 D COG0477 Permeases of the major facilitator superfamily; transporter 2585505..2586788 Escherichia coli O104:H4 str. 2009EL-2050 13688996 YP_006770182.1 CDS O3M_12690 NC_018650.1 2586877 2588337 D COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannonate dehydrogenase 2586877..2588337 Escherichia coli O104:H4 str. 2009EL-2050 13688997 YP_006770183.1 CDS O3M_12695 NC_018650.1 2588373 2588576 R selenoprotein ydfZ complement(2588373..2588576) Escherichia coli O104:H4 str. 2009EL-2050 13688998 YP_006770184.1 CDS O3M_12700 NC_018650.1 2588754 2589440 R COG1802 Transcriptional regulators; hypothetical protein complement(2588754..2589440) Escherichia coli O104:H4 str. 2009EL-2050 13688999 YP_006770185.1 CDS O3M_12705 NC_018650.1 2589529 2590275 R COG4221 Short-chain alcohol dehydrogenase of unknown specificity; malonic semialdehyde reductase complement(2589529..2590275) Escherichia coli O104:H4 str. 2009EL-2050 13689000 YP_006770186.1 CDS O3M_12710 NC_018650.1 2590412 2592457 D COG0339 Zn-dependent oligopeptidases; dipeptidyl carboxypeptidase II 2590412..2592457 Escherichia coli O104:H4 str. 2009EL-2050 13689001 YP_006770187.1 CDS O3M_12715 NC_018650.1 2592502 2593020 R COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein complement(2592502..2593020) Escherichia coli O104:H4 str. 2009EL-2050 13689002 YP_006770188.1 CDS O3M_12720 NC_018650.1 2593296 2593688 D COG3111 Uncharacterized conserved protein; hypothetical protein 2593296..2593688 Escherichia coli O104:H4 str. 2009EL-2050 13689003 YP_006770189.1 CDS O3M_12725 NC_018650.1 2593943 2594833 D COG2199 FOG: GGDEF domain; diguanylate cyclase 2593943..2594833 Escherichia coli O104:H4 str. 2009EL-2050 13689004 YP_006770190.1 CDS O3M_12730 NC_018650.1 2595053 2595148 R hypothetical protein complement(2595053..2595148) Escherichia coli O104:H4 str. 2009EL-2050 13689005 YP_006770191.1 CDS O3M_12735 NC_018650.1 2595275 2596462 R COG0477 Permeases of the major facilitator superfamily; transporter complement(2595275..2596462) Escherichia coli O104:H4 str. 2009EL-2050 13689006 YP_006770192.1 CDS O3M_12740 NC_018650.1 2596657 2597556 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; O-acetylserine/cysteine export protein 2596657..2597556 Escherichia coli O104:H4 str. 2009EL-2050 13689007 YP_006770193.1 CDS O3M_12745 NC_018650.1 2597601 2598299 R COG2188 Transcriptional regulators; transcriptional regulator complement(2597601..2598299) Escherichia coli O104:H4 str. 2009EL-2050 13689008 YP_006770194.1 CDS O3M_12750 NC_018650.1 2598498 2598809 D COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 2598498..2598809 Escherichia coli O104:H4 str. 2009EL-2050 13689009 YP_006770195.1 CDS O3M_12755 NC_018650.1 2598924 2600246 D COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system transporter subunit IIC 2598924..2600246 Escherichia coli O104:H4 str. 2009EL-2050 13689010 YP_006770196.1 CDS O3M_12760 NC_018650.1 2600274 2600585 D COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 2600274..2600585 Escherichia coli O104:H4 str. 2009EL-2050 13689011 YP_006770197.1 CDS O3M_12765 NC_018650.1 2600641 2602314 D COG0789 Predicted transcriptional regulators; carbohydrate-specific outer membrane porin 2600641..2602314 Escherichia coli O104:H4 str. 2009EL-2050 13689012 YP_006770198.1 CDS celA NC_018650.1 2602339 2603778 D COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; 6-phospho-beta-glucosidase 2602339..2603778 Escherichia coli O104:H4 str. 2009EL-2050 13689013 YP_006770199.1 CDS O3M_12775 NC_018650.1 2603835 2604053 R hypothetical protein complement(2603835..2604053) Escherichia coli O104:H4 str. 2009EL-2050 13689014 YP_006770200.1 CDS O3M_12780 NC_018650.1 2604085 2604468 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator MarA complement(2604085..2604468) Escherichia coli O104:H4 str. 2009EL-2050 13689015 YP_006770201.1 CDS O3M_12785 NC_018650.1 2604488 2604922 R COG1846 Transcriptional regulators; DNA-binding transcriptional repressor MarR complement(2604488..2604922) Escherichia coli O104:H4 str. 2009EL-2050 13689016 YP_006770202.1 CDS O3M_12790 NC_018650.1 2605134 2605799 D COG2095 Multiple antibiotic transporter; inner membrane protein 2605134..2605799 Escherichia coli O104:H4 str. 2009EL-2050 13689017 YP_006770203.1 CDS O3M_12795 NC_018650.1 2605824 2607014 R COG2814 Arabinose efflux permease; arabinose transporter complement(2605824..2607014) Escherichia coli O104:H4 str. 2009EL-2050 13689018 YP_006770204.1 CDS O3M_12800 NC_018650.1 2607164 2607412 R hypothetical protein complement(2607164..2607412) Escherichia coli O104:H4 str. 2009EL-2050 13689019 YP_006770205.1 CDS O3M_12805 NC_018650.1 2607819 2608277 R hypothetical protein complement(2607819..2608277) Escherichia coli O104:H4 str. 2009EL-2050 13689020 YP_006770206.1 CDS O3M_12810 NC_018650.1 2608355 2609236 R COG0583 Transcriptional regulator; LysR family transcriptional regulator complement(2608355..2609236) Escherichia coli O104:H4 str. 2009EL-2050 13689021 YP_006770207.1 CDS O3M_12815 NC_018650.1 2609337 2610725 D COG1012 NAD-dependent aldehyde dehydrogenases; succinate-semialdehyde dehydrogenase 2609337..2610725 Escherichia coli O104:H4 str. 2009EL-2050 13689022 YP_006770208.1 CDS O3M_12820 NC_018650.1 2610789 2611715 D COG2066 Glutaminase; glutaminase 2610789..2611715 Escherichia coli O104:H4 str. 2009EL-2050 13689023 YP_006770209.1 CDS O3M_12825 NC_018650.1 2611715 2612074 D hypothetical protein 2611715..2612074 Escherichia coli O104:H4 str. 2009EL-2050 13689024 YP_006770210.1 CDS O3M_12830 NC_018650.1 2612213 2613631 D COG2199 FOG: GGDEF domain; hypothetical protein 2612213..2613631 Escherichia coli O104:H4 str. 2009EL-2050 13689025 YP_006770211.1 CDS O3M_12835 NC_018650.1 2613858 2615309 D COG0246 Mannitol-1-phosphate/altronate dehydrogenases; altronate oxidoreductase 2613858..2615309 Escherichia coli O104:H4 str. 2009EL-2050 13689026 YP_006770212.1 CDS O3M_12840 NC_018650.1 2615516 2616430 D COG3781 Predicted membrane protein; hypothetical protein 2615516..2616430 Escherichia coli O104:H4 str. 2009EL-2050 13689027 YP_006770213.1 CDS O3M_12845 NC_018650.1 2616434 2617192 R COG4106 Trans-aconitate methyltransferase; trans-aconitate 2-methyltransferase complement(2616434..2617192) Escherichia coli O104:H4 str. 2009EL-2050 13689028 YP_006770214.1 CDS O3M_12850 NC_018650.1 2617249 2617539 R COG1359 Uncharacterized conserved protein; autoinducer-2 (AI-2) modifying protein LsrG complement(2617249..2617539) Escherichia coli O104:H4 str. 2009EL-2050 13689029 YP_006770215.1 CDS O3M_12855 NC_018650.1 2617563 2618438 R COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes; autoinducer 2 aldolase complement(2617563..2618438) Escherichia coli O104:H4 str. 2009EL-2050 13689030 YP_006770216.1 CDS O3M_12860 NC_018650.1 2618465 2619487 R COG1879 ABC-type sugar transport system, periplasmic component; autoinducer 2-binding protein lsrB complement(2618465..2619487) Escherichia coli O104:H4 str. 2009EL-2050 13689031 YP_006770217.1 CDS O3M_12865 NC_018650.1 2619499 2620491 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; autoinducer 2 import system permease LsrD complement(2619499..2620491) Escherichia coli O104:H4 str. 2009EL-2050 13689032 YP_006770218.1 CDS O3M_12870 NC_018650.1 2620491 2621519 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; autoinducer 2 ABC transporter permease LsrC complement(2620491..2621519) Escherichia coli O104:H4 str. 2009EL-2050 13689033 YP_006770219.1 CDS O3M_12875 NC_018650.1 2621513 2623048 R COG1129 ABC-type sugar transport system, ATPase component; autoinducer 2 ABC transporter ATP-binding protein LsrA complement(2621513..2623048) Escherichia coli O104:H4 str. 2009EL-2050 13689034 YP_006770220.1 CDS O3M_12880 NC_018650.1 2623297 2624250 D COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; transcriptional regulator LsrR 2623297..2624250 Escherichia coli O104:H4 str. 2009EL-2050 13689035 YP_006770221.1 CDS O3M_12885 NC_018650.1 2624329 2625921 D COG1070 Sugar (pentulose and hexulose) kinases; autoinducer-2 (AI-2) kinase 2624329..2625921 Escherichia coli O104:H4 str. 2009EL-2050 13689036 YP_006770222.1 CDS O3M_12890 NC_018650.1 2626452 2630429 D COG5295 Autotransporter adhesin; lipoprotein 2626452..2630429 Escherichia coli O104:H4 str. 2009EL-2050 13689037 YP_006770223.1 CDS O3M_12895 NC_018650.1 2630473 2631873 D COG3468 Type V secretory pathway, adhesin AidA; lipoprotein/autotransporter domain-containing protein 2630473..2631873 Escherichia coli O104:H4 str. 2009EL-2050 13689038 YP_006770224.1 CDS O3M_12900 NC_018650.1 2632082 2632348 D COG1396 Predicted transcriptional regulators; antitoxin HipB 2632082..2632348 Escherichia coli O104:H4 str. 2009EL-2050 13689039 YP_006770225.1 CDS O3M_12905 NC_018650.1 2632348 2633670 D COG3550 Uncharacterized protein related to capsule biosynthesis enzymes; regulator with hipB 2632348..2633670 Escherichia coli O104:H4 str. 2009EL-2050 13689040 YP_006770226.1 CDS O3M_12910 NC_018650.1 2633988 2634167 D COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator 2633988..2634167 Escherichia coli O104:H4 str. 2009EL-2050 13689041 YP_006770227.1 CDS O3M_12915 NC_018650.1 2634623 2635186 D COG3539 P pilus assembly protein, pilin FimA; major fimbrial subunit FmlA 2634623..2635186 Escherichia coli O104:H4 str. 2009EL-2050 13689042 YP_006770228.1 CDS O3M_12920 NC_018650.1 2635520 2636230 D COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein 2635520..2636230 Escherichia coli O104:H4 str. 2009EL-2050 13689043 YP_006770229.1 CDS O3M_12925 NC_018650.1 2636272 2638923 D COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 2636272..2638923 Escherichia coli O104:H4 str. 2009EL-2050 13689044 YP_006770230.1 CDS O3M_12930 NC_018650.1 2638937 2639467 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 2638937..2639467 Escherichia coli O104:H4 str. 2009EL-2050 13689045 YP_006770231.1 CDS O3M_12935 NC_018650.1 2639480 2639983 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 2639480..2639983 Escherichia coli O104:H4 str. 2009EL-2050 13689046 YP_006770232.1 CDS O3M_12940 NC_018650.1 2640042 2640956 D fimbrial-like adhesin protein 2640042..2640956 Escherichia coli O104:H4 str. 2009EL-2050 13689047 YP_006770233.1 CDS O3M_12945 NC_018650.1 2641290 2643569 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase 2641290..2643569 Escherichia coli O104:H4 str. 2009EL-2050 13689048 YP_006770234.1 CDS O3M_12950 NC_018650.1 2643817 2644014 D hypothetical protein 2643817..2644014 Escherichia coli O104:H4 str. 2009EL-2050 13689049 YP_006770235.1 CDS O3M_12955 NC_018650.1 2644089 2644850 D COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator YdeO 2644089..2644850 Escherichia coli O104:H4 str. 2009EL-2050 13689050 YP_006770236.1 CDS O3M_12960 NC_018650.1 2645252 2645761 D COG3119 Arylsulfatase A and related enzymes; sulfatase 2645252..2645761 Escherichia coli O104:H4 str. 2009EL-2050 13689051 YP_006770237.1 CDS O3M_12965 NC_018650.1 2645807 2646787 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 2645807..2646787 Escherichia coli O104:H4 str. 2009EL-2050 13689052 YP_006770238.1 CDS O3M_12970 NC_018650.1 2646949 2648133 D COG3119 Arylsulfatase A and related enzymes; hypothetical protein 2646949..2648133 Escherichia coli O104:H4 str. 2009EL-2050 13689053 YP_006770239.1 CDS O3M_12975 NC_018650.1 2648185 2649342 D COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); hypothetical protein 2648185..2649342 Escherichia coli O104:H4 str. 2009EL-2050 13689054 YP_006770240.1 CDS O3M_12980 NC_018650.1 2649633 2651318 D permease and ATP-binding component; COG4178 ABC-type uncharacterized transport system, permease and ATPase components; multidrug ABC transporter 2649633..2651318 Escherichia coli O104:H4 str. 2009EL-2050 13689055 YP_006770241.1 CDS O3M_12985 NC_018650.1 2651356 2653728 D COG1629 Outer membrane receptor proteins, mostly Fe transport; porin protein 2651356..2653728 Escherichia coli O104:H4 str. 2009EL-2050 13689056 YP_006770242.1 CDS O3M_12990 NC_018650.1 2653773 2656568 D COG0612 Predicted Zn-dependent peptidases; membrane-associated peptidase 2653773..2656568 Escherichia coli O104:H4 str. 2009EL-2050 13689057 YP_006770243.1 CDS O3M_12995 NC_018650.1 2656930 2658330 D COG0076 Glutamate decarboxylase and related PLP-dependent proteins; glutamate decarboxylase 2656930..2658330 Escherichia coli O104:H4 str. 2009EL-2050 13689058 YP_006770244.1 CDS O3M_13000 NC_018650.1 2658486 2660021 D COG0531 Amino acid transporters; glutamate/gamma-aminobutyrate antiporter 2658486..2660021 Escherichia coli O104:H4 str. 2009EL-2050 13689059 YP_006770245.1 CDS O3M_13005 NC_018650.1 2660152 2661471 D COG1649 Uncharacterized protein conserved in bacteria; lipoprotein 2660152..2661471 Escherichia coli O104:H4 str. 2009EL-2050 13689060 YP_006770246.1 CDS O3M_13010 NC_018650.1 2661843 2663225 D COG2199 FOG: GGDEF domain; diguanylate cyclase 2661843..2663225 Escherichia coli O104:H4 str. 2009EL-2050 13689061 YP_006770247.1 CDS O3M_13015 NC_018650.1 2663250 2665649 D COG2202 FOG: PAS/PAC domain; cyclic-di-GMP phosphodiesterase 2663250..2665649 Escherichia coli O104:H4 str. 2009EL-2050 13689062 YP_006770248.1 CDS O3M_13020 NC_018650.1 2665907 2666488 D COG2173 D-alanyl-D-alanine dipeptidase; D-alanyl-D-alanine dipeptidase 2665907..2666488 Escherichia coli O104:H4 str. 2009EL-2050 13689063 YP_006770249.1 CDS O3M_13025 NC_018650.1 2666502 2668052 D periplasmic-binding component of ABC superfamily protein; COG0747 ABC-type dipeptide transport system, periplasmic component; D-ala-D-a la transporter subunit 2666502..2668052 Escherichia coli O104:H4 str. 2009EL-2050 13689064 YP_006770250.1 CDS O3M_13030 NC_018650.1 2668054 2669076 D COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport system inner membrane protein 2668054..2669076 Escherichia coli O104:H4 str. 2009EL-2050 13689065 YP_006770251.1 CDS O3M_13035 NC_018650.1 2669073 2669969 D COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; D-ala-D-ala transporter subunit 2669073..2669969 Escherichia coli O104:H4 str. 2009EL-2050 13689066 YP_006770252.1 CDS O3M_13040 NC_018650.1 2669966 2670952 D ATP-binding component of ABC superfamily protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; D-ala-D-ala transporter subunit 2669966..2670952 Escherichia coli O104:H4 str. 2009EL-2050 13689067 YP_006770253.1 CDS O3M_13045 NC_018650.1 2670945 2671871 D ATP-binding component of ABC superfamily protein; COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; D-ala-D-ala transporter subunit 2670945..2671871 Escherichia coli O104:H4 str. 2009EL-2050 13689068 YP_006770254.1 CDS O3M_13050 NC_018650.1 2671927 2672358 R COG1764 Predicted redox protein, regulator of disulfide bond formation; osmotically inducible, stress-inducible membrane protein OsmC complement(2671927..2672358) Escherichia coli O104:H4 str. 2009EL-2050 13689069 YP_006770255.1 CDS O3M_13055 NC_018650.1 2672704 2672919 D biofilm-dependent modulation protein 2672704..2672919 Escherichia coli O104:H4 str. 2009EL-2050 13689070 YP_006770256.1 CDS rpsV NC_018650.1 2673021 2673158 D 30S ribosomal subunit S22 2673021..2673158 Escherichia coli O104:H4 str. 2009EL-2050 13689071 YP_006770257.1 CDS O3M_13065 NC_018650.1 2673315 2675012 D COG0281 Malic enzyme; malate dehydrogenase 2673315..2675012 Escherichia coli O104:H4 str. 2009EL-2050 13689072 YP_006770258.1 CDS O3M_13070 NC_018650.1 2675146 2676156 D COG1064 Zn-dependent alcohol dehydrogenases; ethanol-active dehydrogenase/acetaldehyde-active reductase 2675146..2676156 Escherichia coli O104:H4 str. 2009EL-2050 13689073 YP_006770259.1 CDS O3M_13075 NC_018650.1 2676303 2676587 D COG3093 Plasmid maintenance system antidote protein; DNA-binding transcriptional regulator 2676303..2676587 Escherichia coli O104:H4 str. 2009EL-2050 13689074 YP_006770260.1 CDS O3M_13080 NC_018650.1 2676638 2677291 R COG2864 Cytochrome b subunit of formate dehydrogenase; formate dehydrogenase-N subunit gamma complement(2676638..2677291) Escherichia coli O104:H4 str. 2009EL-2050 13689075 YP_006770261.1 CDS O3M_13085 NC_018650.1 2677284 2678168 R COG0437 Fe-S-cluster-containing hydrogenase components 1; formate dehydrogenase, nitrate-inducible, iron-sulfur subunit complement(2677284..2678168) Escherichia coli O104:H4 str. 2009EL-2050 13689076 YP_006770262.1 CDS O3M_13100 NC_018650.1 2681460 2682341 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; aromatic amino acid exporter 2681460..2682341 Escherichia coli O104:H4 str. 2009EL-2050 13689077 YP_006770263.1 CDS O3M_13105 NC_018650.1 2682600 2682890 D COG3203 Outer membrane protein (porin); lipoprotein 2682600..2682890 Escherichia coli O104:H4 str. 2009EL-2050 13689078 YP_006770264.1 CDS O3M_13110 NC_018650.1 2682914 2684245 D COG4886 Leucine-rich repeat (LRR) protein; glycoprotein with ribonuclease inhibitor domain (yddK, modular protein) 2682914..2684245 Escherichia coli O104:H4 str. 2009EL-2050 13689079 YP_006770265.1 CDS O3M_13115 NC_018650.1 2684569 2685957 D COG2223 Nitrate/nitrite transporter; nitrate/nitrite transport protein NarU 2684569..2685957 Escherichia coli O104:H4 str. 2009EL-2050 13689080 YP_006770266.1 CDS O3M_13120 NC_018650.1 2686039 2689779 D COG5013 Nitrate reductase alpha subunit; nitrate reductase 2 subunit alpha 2686039..2689779 Escherichia coli O104:H4 str. 2009EL-2050 13689081 YP_006770267.1 CDS O3M_13125 NC_018650.1 2689776 2691320 D COG1140 Nitrate reductase beta subunit; nitrate reductase 2 (NRZ) subunit beta 2689776..2691320 Escherichia coli O104:H4 str. 2009EL-2050 13689082 YP_006770268.1 CDS O3M_13130 NC_018650.1 2691320 2692015 D COG2180 Nitrate reductase delta subunit; nitrate reductase 2 subunit delta 2691320..2692015 Escherichia coli O104:H4 str. 2009EL-2050 13689083 YP_006770269.1 CDS O3M_13135 NC_018650.1 2692012 2692692 D COG2181 Nitrate reductase gamma subunit; nitrate reductase 2 (NRZ) subunit gamma 2692012..2692692 Escherichia coli O104:H4 str. 2009EL-2050 13689084 YP_006770270.1 CDS O3M_13140 NC_018650.1 2692771 2693664 D COG0384 Predicted epimerase, PhzC/PhzF homolog; hypothetical protein 2692771..2693664 Escherichia coli O104:H4 str. 2009EL-2050 13689085 YP_006770271.1 CDS O3M_13145 NC_018650.1 2693760 2694605 R COG2162 Arylamine N-acetyltransferase; N-hydroxyarylamine O-acetyltransferase complement(2693760..2694605) Escherichia coli O104:H4 str. 2009EL-2050 13689086 YP_006770272.1 CDS O3M_13150 NC_018650.1 2694778 2695347 D COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein 2694778..2695347 Escherichia coli O104:H4 str. 2009EL-2050 13689087 YP_006770273.1 CDS O3M_13155 NC_018650.1 2695351 2695578 R COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; 4-oxalocrotonate tautomerase complement(2695351..2695578) Escherichia coli O104:H4 str. 2009EL-2050 13689088 YP_006770274.1 CDS O3M_13160 NC_018650.1 2695611 2696309 R COG5433 Transposase; H repeat-associated protein complement(2695611..2696309) Escherichia coli O104:H4 str. 2009EL-2050 13689089 YP_006770275.1 CDS O3M_13165 NC_018650.1 2696663 2697109 R hypothetical protein complement(2696663..2697109) Escherichia coli O104:H4 str. 2009EL-2050 13689090 YP_006770276.1 CDS O3M_13170 NC_018650.1 2697124 2701365 R COG3209 Rhs family protein; rhsD element protein complement(2697124..2701365) Escherichia coli O104:H4 str. 2009EL-2050 13689091 YP_006770277.1 CDS O3M_13175 NC_018650.1 2701433 2703541 R Encoded within repeats that are hotspots for chromosomal duplication formation: Function unknown; COG3501 Uncharacterized protein conserved in bacteria; VgrG protein complement(2701433..2703541) Escherichia coli O104:H4 str. 2009EL-2050 13689092 YP_006770278.1 CDS O3M_13180 NC_018650.1 2704361 2704573 R hypothetical protein complement(2704361..2704573) Escherichia coli O104:H4 str. 2009EL-2050 13689093 YP_006770279.1 CDS O3M_13185 NC_018650.1 2704649 2705266 R COG0625 Glutathione S-transferase; glutathione S-transferase-like protein complement(2704649..2705266) Escherichia coli O104:H4 str. 2009EL-2050 13689094 YP_006770280.1 CDS O3M_13190 NC_018650.1 2705533 2707032 D COG1113 Gamma-aminobutyrate permease and related permeases; L-asparagine permease 2705533..2707032 Escherichia coli O104:H4 str. 2009EL-2050 13689095 YP_006770281.1 CDS O3M_13195 NC_018650.1 2707145 2708206 R COG3391 Uncharacterized conserved protein; hypothetical protein complement(2707145..2708206) Escherichia coli O104:H4 str. 2009EL-2050 13689096 YP_006770282.1 CDS O3M_13200 NC_018650.1 2708448 2710550 D COG1629 Outer membrane receptor proteins, mostly Fe transport; iron outer membrane receptor 2708448..2710550 Escherichia coli O104:H4 str. 2009EL-2050 13689097 YP_006770283.1 CDS O3M_13205 NC_018650.1 2710586 2711251 R COG1802 Transcriptional regulators; colanic acid/biofilm transcriptional regulator complement(2710586..2711251) Escherichia coli O104:H4 str. 2009EL-2050 13689098 YP_006770284.1 CDS O3M_13210 NC_018650.1 2711449 2712486 R COG2130 Putative NADP-dependent oxidoreductases; oxidoreductase complement(2711449..2712486) Escherichia coli O104:H4 str. 2009EL-2050 13689099 YP_006770285.1 CDS O3M_13215 NC_018650.1 2712667 2713185 D COG1247 Sortase and related acyltransferases; acyl-CoA N-acyltransferase 2712667..2713185 Escherichia coli O104:H4 str. 2009EL-2050 13689100 YP_006770286.1 CDS O3M_13220 NC_018650.1 2713182 2713631 D COG3238 Uncharacterized protein conserved in bacteria; inner membrane protein 2713182..2713631 Escherichia coli O104:H4 str. 2009EL-2050 13689101 YP_006770287.1 CDS O3M_13225 NC_018650.1 2713632 2713865 R hypothetical protein complement(2713632..2713865) Escherichia coli O104:H4 str. 2009EL-2050 13689102 YP_006770288.1 CDS O3M_13230 NC_018650.1 2713951 2714124 R hypothetical protein complement(2713951..2714124) Escherichia coli O104:H4 str. 2009EL-2050 13689103 YP_006770289.1 CDS O3M_13235 NC_018650.1 2714816 2715625 R COG0110 Acetyltransferase (isoleucine patch superfamily); acetyltransferase complement(2714816..2715625) Escherichia coli O104:H4 str. 2009EL-2050 13689104 YP_006770290.1 CDS O3M_13240 NC_018650.1 2715835 2717259 R COG1012 NAD-dependent aldehyde dehydrogenases; gamma-aminobutyraldehyde dehydrogenase complement(2715835..2717259) Escherichia coli O104:H4 str. 2009EL-2050 13689105 YP_006770291.1 CDS O3M_13245 NC_018650.1 2717281 2718075 R COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease complement(2717281..2718075) Escherichia coli O104:H4 str. 2009EL-2050 13689106 YP_006770292.1 CDS O3M_13250 NC_018650.1 2718065 2719006 R COG1176 ABC-type spermidine/putrescine transport system, permease component I; ABC transporter permease complement(2718065..2719006) Escherichia coli O104:H4 str. 2009EL-2050 13689107 YP_006770293.1 CDS O3M_13255 NC_018650.1 2719007 2720020 R ATP-binding component of ABC superfamily transporter; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine transporter subunit complement(2719007..2720020) Escherichia coli O104:H4 str. 2009EL-2050 13689108 YP_006770294.1 CDS O3M_13260 NC_018650.1 2720038 2721183 R COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine transporter subunit complement(2720038..2721183) Escherichia coli O104:H4 str. 2009EL-2050 13689109 YP_006770295.1 CDS O3M_13265 NC_018650.1 2721428 2722834 R COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; DNA-binding transcriptional regulator complement(2721428..2722834) Escherichia coli O104:H4 str. 2009EL-2050 13689110 YP_006770296.1 CDS O3M_13270 NC_018650.1 2722913 2723350 R COG1598 Uncharacterized conserved protein; DNA-binding transcriptional regulator complement(2722913..2723350) Escherichia coli O104:H4 str. 2009EL-2050 13689111 YP_006770297.1 CDS O3M_13275 NC_018650.1 2723751 2723981 D hypothetical protein 2723751..2723981 Escherichia coli O104:H4 str. 2009EL-2050 13689112 YP_006770298.1 CDS O3M_13280 NC_018650.1 2724073 2726034 R COG0826 Collagenase and related proteases; peptidase, U32 family protein complement(2724073..2726034) Escherichia coli O104:H4 str. 2009EL-2050 13689113 YP_006770299.1 CDS O3M_13285 NC_018650.1 2726107 2726643 R COG1396 Predicted transcriptional regulators; DNA-binding transcriptional regulator complement(2726107..2726643) Escherichia coli O104:H4 str. 2009EL-2050 13689114 YP_006770300.1 CDS O3M_13290 NC_018650.1 2726735 2727910 D COG3135 Uncharacterized protein involved in benzoate metabolism; benzoate transporter 2726735..2727910 Escherichia coli O104:H4 str. 2009EL-2050 13689115 YP_006770301.1 CDS O3M_13295 NC_018650.1 2727950 2729158 R COG0675 Transposase and inactivated derivatives; transposase complement(2727950..2729158) Escherichia coli O104:H4 str. 2009EL-2050 13689116 YP_006770302.1 CDS O3M_13310 NC_018650.1 2729685 2730353 R hypothetical protein complement(2729685..2730353) Escherichia coli O104:H4 str. 2009EL-2050 13689117 YP_006770303.1 CDS O3M_13315 NC_018650.1 2730656 2731249 R COG0500 SAM-dependent methyltransferases; tellurite resistance protein TehB complement(2730656..2731249) Escherichia coli O104:H4 str. 2009EL-2050 13689118 YP_006770304.1 CDS O3M_13320 NC_018650.1 2731246 2732238 R COG1275 Tellurite resistance protein and related permeases; potassium-tellurite ethidium and proflavin transporter complement(2731246..2732238) Escherichia coli O104:H4 str. 2009EL-2050 13689119 YP_006770305.1 CDS O3M_13325 NC_018650.1 2732362 2733342 D COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; hypothetical protein 2732362..2733342 Escherichia coli O104:H4 str. 2009EL-2050 13689120 YP_006770306.1 CDS O3M_13330 NC_018650.1 2733337 2733873 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-L7/L12-serine acetyltransferase complement(2733337..2733873) Escherichia coli O104:H4 str. 2009EL-2050 13689121 YP_006770307.1 CDS O3M_13335 NC_018650.1 2733936 2734160 R COG2841 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2733936..2734160) Escherichia coli O104:H4 str. 2009EL-2050 13689122 YP_006770308.1 CDS O3M_13340 NC_018650.1 2734176 2734379 D hypothetical protein 2734176..2734379 Escherichia coli O104:H4 str. 2009EL-2050 13689123 YP_006770309.1 CDS mdoD NC_018650.1 2734300 2735955 R COG3131 Periplasmic glucans biosynthesis protein; glucan biosynthesis protein D complement(2734300..2735955) Escherichia coli O104:H4 str. 2009EL-2050 13689124 YP_006770310.1 CDS O3M_13350 NC_018650.1 2736180 2737523 R COG5383 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2736180..2737523) Escherichia coli O104:H4 str. 2009EL-2050 13689125 YP_006770311.1 CDS O3M_13355 NC_018650.1 2737740 2738663 D COG0583 Transcriptional regulator; transcriptional regulator 2737740..2738663 Escherichia coli O104:H4 str. 2009EL-2050 13689126 YP_006770312.1 CDS O3M_13360 NC_018650.1 2738701 2740341 R COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor complement(2738701..2740341) Escherichia coli O104:H4 str. 2009EL-2050 13689127 YP_006770313.1 CDS O3M_13365 NC_018650.1 2740740 2740889 D small toxic polypeptide 2740740..2740889 Escherichia coli O104:H4 str. 2009EL-2050 13689128 YP_006770314.1 CDS O3M_13370 NC_018650.1 2740961 2741134 R hypothetical protein complement(2740961..2741134) Escherichia coli O104:H4 str. 2009EL-2050 13689129 YP_006770315.1 CDS O3M_13375 NC_018650.1 2741379 2741909 R COG3038 Cytochrome B561; cytochrome b561 complement(2741379..2741909) Escherichia coli O104:H4 str. 2009EL-2050 13689130 YP_006770316.1 CDS O3M_13380 NC_018650.1 2742098 2743099 D COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2742098..2743099 Escherichia coli O104:H4 str. 2009EL-2050 13689131 YP_006770317.1 CDS O3M_13385 NC_018650.1 2743141 2744580 R COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase A complement(2743141..2744580) Escherichia coli O104:H4 str. 2009EL-2050 13689132 YP_006770318.1 CDS O3M_13390 NC_018650.1 2744777 2745577 R COG1434 Uncharacterized conserved protein; hypothetical protein complement(2744777..2745577) Escherichia coli O104:H4 str. 2009EL-2050 13689133 YP_006770319.1 CDS O3M_13395 NC_018650.1 2745759 2746262 R COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 complement(2745759..2746262) Escherichia coli O104:H4 str. 2009EL-2050 13689134 YP_006770320.1 CDS O3M_13400 NC_018650.1 2746181 2746456 R COG3677 Transposase and inactivated derivatives; InsA complement(2746181..2746456) Escherichia coli O104:H4 str. 2009EL-2050 13689135 YP_006770321.1 CDS O3M_13405 NC_018650.1 2746625 2750470 R COG1643 HrpA-like helicases; ATP-dependent RNA helicase HrpA complement(2746625..2750470) Escherichia coli O104:H4 str. 2009EL-2050 13689136 YP_006770322.1 CDS O3M_13410 NC_018650.1 2750728 2751333 D COG1182 Acyl carrier protein phosphodiesterase; azoreductase 2750728..2751333 Escherichia coli O104:H4 str. 2009EL-2050 13689137 YP_006770323.1 CDS O3M_13415 NC_018650.1 2751384 2752676 R COG0671 Membrane-associated phospholipid phosphatase; membrane associated phosphatase complement(2751384..2752676) Escherichia coli O104:H4 str. 2009EL-2050 13689138 YP_006770324.1 CDS O3M_13420 NC_018650.1 2752690 2754447 R COG2267 Lysophospholipase; hydrolase complement(2752690..2754447) Escherichia coli O104:H4 str. 2009EL-2050 13689139 YP_006770325.1 CDS O3M_13425 NC_018650.1 2754463 2755359 R COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; membrane associated CTP-phosphosubstrate transferase complement(2754463..2755359) Escherichia coli O104:H4 str. 2009EL-2050 13689140 YP_006770326.1 CDS O3M_13430 NC_018650.1 2755359 2755964 R COG0558 Phosphatidylglycerophosphate synthase; inner membrane protein complement(2755359..2755964) Escherichia coli O104:H4 str. 2009EL-2050 13689141 YP_006770327.1 CDS O3M_13435 NC_018650.1 2756135 2758441 R hypothetical protein complement(2756135..2758441) Escherichia coli O104:H4 str. 2009EL-2050 13689142 YP_006770328.1 CDS O3M_13440 NC_018650.1 2758505 2759365 R COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase complement(2758505..2759365) Escherichia coli O104:H4 str. 2009EL-2050 13689143 YP_006770329.1 CDS O3M_13445 NC_018650.1 2759595 2760185 R COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; hexapeptide repeat acetyltransferase complement(2759595..2760185) Escherichia coli O104:H4 str. 2009EL-2050 13689144 YP_006770330.1 CDS O3M_13450 NC_018650.1 2760167 2761117 R COG3327 Phenylacetic acid-responsive transcriptional repressor; DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive complement(2760167..2761117) Escherichia coli O104:H4 str. 2009EL-2050 13689145 YP_006770331.1 CDS O3M_13455 NC_018650.1 2761218 2762531 R COG1541 Coenzyme F390 synthetase; phenylacetate-CoA ligase complement(2761218..2762531) Escherichia coli O104:H4 str. 2009EL-2050 13689146 YP_006770332.1 CDS O3M_13460 NC_018650.1 2762558 2763763 R COG0183 Acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase complement(2762558..2763763) Escherichia coli O104:H4 str. 2009EL-2050 13689147 YP_006770333.1 CDS O3M_13465 NC_018650.1 2763763 2764185 R COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; thioesterase complement(2763763..2764185) Escherichia coli O104:H4 str. 2009EL-2050 13689148 YP_006770334.1 CDS O3M_13470 NC_018650.1 2764175 2765602 R COG1250 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase complement(2764175..2765602) Escherichia coli O104:H4 str. 2009EL-2050 13689149 YP_006770335.1 CDS O3M_13475 NC_018650.1 2765604 2766392 R COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase complement(2765604..2766392) Escherichia coli O104:H4 str. 2009EL-2050 13689150 YP_006770336.1 CDS O3M_13480 NC_018650.1 2766392 2767159 R COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase-isomerase complement(2766392..2767159) Escherichia coli O104:H4 str. 2009EL-2050 13689151 YP_006770337.1 CDS O3M_13485 NC_018650.1 2767156 2768226 R COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; subunit of the phenylacetly-CoA oxygenase/reductase complement(2767156..2768226) Escherichia coli O104:H4 str. 2009EL-2050 13689152 YP_006770338.1 CDS O3M_13490 NC_018650.1 2768234 2768731 R COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; multicomponent oxygenase/reductase subunit complement(2768234..2768731) Escherichia coli O104:H4 str. 2009EL-2050 13689153 YP_006770339.1 CDS O3M_13495 NC_018650.1 2768746 2769492 R COG3396 Uncharacterized conserved protein; multicomponent oxygenase/reductase subunit complement(2768746..2769492) Escherichia coli O104:H4 str. 2009EL-2050 13689154 YP_006770340.1 CDS paaB NC_018650.1 2769501 2769788 R COG3460 Uncharacterized enzyme of phenylacetate metabolism; phenylacetate-CoA oxygenase subunit PaaB complement(2769501..2769788) Escherichia coli O104:H4 str. 2009EL-2050 13689155 YP_006770341.1 CDS paaA NC_018650.1 2769800 2770729 R COG3396 Uncharacterized conserved protein; phenylacetate-CoA oxygenase subunit PaaA complement(2769800..2770729) Escherichia coli O104:H4 str. 2009EL-2050 13689156 YP_006770342.1 CDS O3M_13510 NC_018650.1 2771014 2773059 D COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 2771014..2773059 Escherichia coli O104:H4 str. 2009EL-2050 13689157 YP_006770343.1 CDS tynA NC_018650.1 2773307 2775580 D COG3733 Cu2+-containing amine oxidase; tyramine oxidase 2773307..2775580 Escherichia coli O104:H4 str. 2009EL-2050 13689158 YP_006770344.1 CDS O3M_13520 NC_018650.1 2775638 2777137 R COG1012 NAD-dependent aldehyde dehydrogenases; phenylacetaldehyde dehydrogenase complement(2775638..2777137) Escherichia coli O104:H4 str. 2009EL-2050 13689159 YP_006770345.1 CDS O3M_13525 NC_018650.1 2777373 2778278 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator FeaR 2777373..2778278 Escherichia coli O104:H4 str. 2009EL-2050 13689160 YP_006770346.1 CDS O3M_13530 NC_018650.1 2778450 2778776 R COG3784 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2778450..2778776) Escherichia coli O104:H4 str. 2009EL-2050 13689161 YP_006770347.1 CDS O3M_13535 NC_018650.1 2778784 2778969 R lipoprotein complement(2778784..2778969) Escherichia coli O104:H4 str. 2009EL-2050 13689162 YP_006770348.1 CDS O3M_13540 NC_018650.1 2778966 2781605 R hypothetical protein complement(2778966..2781605) Escherichia coli O104:H4 str. 2009EL-2050 13689163 YP_006770349.1 CDS O3M_13545 NC_018650.1 2781813 2782802 D COG1052 Lactate dehydrogenase and related dehydrogenases; D-lactate dehydrogenase 2781813..2782802 Escherichia coli O104:H4 str. 2009EL-2050 13689164 YP_006770350.1 CDS O3M_13550 NC_018650.1 2782913 2783335 D COG3187 Heat shock protein; heat-inducible protein 2782913..2783335 Escherichia coli O104:H4 str. 2009EL-2050 13689165 YP_006770351.1 CDS O3M_13555 NC_018650.1 2783332 2783598 R COG3042 Putative hemolysin; hypothetical protein complement(2783332..2783598) Escherichia coli O104:H4 str. 2009EL-2050 13689166 YP_006770352.1 CDS O3M_13560 NC_018650.1 2783872 2787396 D 4Fe-4S cluster binding protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; fused 2-oxoacid-flavodoxin oxidoreductase/hypothetical protein 2783872..2787396 Escherichia coli O104:H4 str. 2009EL-2050 13689167 YP_006770353.1 CDS O3M_13565 NC_018650.1 2787763 2788896 D COG3203 Outer membrane protein (porin); outer membrane pore protein N, non-specific 2787763..2788896 Escherichia coli O104:H4 str. 2009EL-2050 13689168 YP_006770354.1 CDS O3M_13570 NC_018650.1 2789037 2789471 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein F 2789037..2789471 Escherichia coli O104:H4 str. 2009EL-2050 13689169 YP_006770355.1 CDS O3M_13575 NC_018650.1 2789647 2790582 D COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA 2-thiocytidine biosynthesis protein TtcA 2789647..2790582 Escherichia coli O104:H4 str. 2009EL-2050 13689170 YP_006770356.1 CDS O3M_13580 NC_018650.1 2790711 2792084 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase DbpA complement(2790711..2792084) Escherichia coli O104:H4 str. 2009EL-2050 13689171 YP_006770357.1 CDS O3M_13585 NC_018650.1 2792114 2792287 R hypothetical protein complement(2792114..2792287) Escherichia coli O104:H4 str. 2009EL-2050 13689172 YP_006770358.1 CDS zntB NC_018650.1 2792562 2793545 R COG0598 Mg2+ and Co2+ transporters; zinc transporter complement(2792562..2793545) Escherichia coli O104:H4 str. 2009EL-2050 13689173 YP_006770359.1 CDS O3M_13595 NC_018650.1 2793800 2795032 D COG2199 FOG: GGDEF domain; hypothetical protein 2793800..2795032 Escherichia coli O104:H4 str. 2009EL-2050 13689174 YP_006770360.1 CDS O3M_13600 NC_018650.1 2795053 2795616 R COG2840 Uncharacterized protein conserved in bacteria; Smr domain-containing protein complement(2795053..2795616) Escherichia coli O104:H4 str. 2009EL-2050 13689175 YP_006770361.1 CDS O3M_13605 NC_018650.1 2795946 2796854 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator complement(2795946..2796854) Escherichia coli O104:H4 str. 2009EL-2050 13689176 YP_006770362.1 CDS O3M_13610 NC_018650.1 2797030 2798340 D COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; peptidase, aminobenzoyl-glutamate utilization protein AbgA 2797030..2798340 Escherichia coli O104:H4 str. 2009EL-2050 13689177 YP_006770363.1 CDS O3M_13615 NC_018650.1 2798340 2799785 D COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; peptidase, aminobenzoyl-glutamate utilization protein AbgB 2798340..2799785 Escherichia coli O104:H4 str. 2009EL-2050 13689178 YP_006770364.1 CDS abgT NC_018650.1 2799822 2801348 D COG2978 Putative p-aminobenzoyl-glutamate transporter; aminobenzoyl-glutamate transporter 2799822..2801348 Escherichia coli O104:H4 str. 2009EL-2050 13689179 YP_006770365.1 CDS O3M_13625 NC_018650.1 2801359 2801874 D COG0350 Methylated DNA-protein cysteine methyltransferase; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 2801359..2801874 Escherichia coli O104:H4 str. 2009EL-2050 13689180 YP_006770366.1 CDS O3M_13630 NC_018650.1 2802069 2802821 D COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; fumarate/nitrate reduction transcriptional regulator 2802069..2802821 Escherichia coli O104:H4 str. 2009EL-2050 13689181 YP_006770367.1 CDS O3M_13635 NC_018650.1 2802973 2803923 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspE 2802973..2803923 Escherichia coli O104:H4 str. 2009EL-2050 13689182 YP_006770368.1 CDS O3M_13640 NC_018650.1 2803973 2804230 R hypothetical protein complement(2803973..2804230) Escherichia coli O104:H4 str. 2009EL-2050 13689183 YP_006770369.1 CDS O3M_13645 NC_018650.1 2804474 2805505 D COG0668 Small-conductance mechanosensitive channel; MscS family inner membrane protein YnaI 2804474..2805505 Escherichia coli O104:H4 str. 2009EL-2050 13689184 YP_006770370.1 CDS O3M_13650 NC_018650.1 2805556 2807169 R COG4166 ABC-type oligopeptide transport system, periplasmic component; transport periplasmic protein complement(2805556..2807169) Escherichia coli O104:H4 str. 2009EL-2050 13689185 YP_006770371.1 CDS O3M_13655 NC_018650.1 2807292 2807417 R hypothetical protein complement(2807292..2807417) Escherichia coli O104:H4 str. 2009EL-2050 13689186 YP_006770372.1 CDS O3M_13660 NC_018650.1 2807506 2808405 R COG0583 Transcriptional regulator; LysR family transcriptional regulator complement(2807506..2808405) Escherichia coli O104:H4 str. 2009EL-2050 13689187 YP_006770373.1 CDS O3M_13665 NC_018650.1 2808531 2809463 D COG1073 Hydrolases of the alpha/beta superfamily; hydrolase 2808531..2809463 Escherichia coli O104:H4 str. 2009EL-2050 13689188 YP_006770374.1 CDS O3M_13670 NC_018650.1 2809534 2809698 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 2809534..2809698 Escherichia coli O104:H4 str. 2009EL-2050 13689189 YP_006770375.1 CDS O3M_13675 NC_018650.1 2809799 2810527 D COG2866 Predicted carboxypeptidase; murein peptide amidase A 2809799..2810527 Escherichia coli O104:H4 str. 2009EL-2050 13689190 YP_006770376.1 CDS O3M_13680 NC_018650.1 2810502 2811467 R COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; L-Ala-D/L-Glu epimerase complement(2810502..2811467) Escherichia coli O104:H4 str. 2009EL-2050 13689191 YP_006770377.1 CDS tpx NC_018650.1 2811586 2812092 D COG2077 Peroxiredoxin; lipid hydroperoxide peroxidase 2811586..2812092 Escherichia coli O104:H4 str. 2009EL-2050 13689192 YP_006770378.1 CDS O3M_13690 NC_018650.1 2812136 2813677 R COG3283 Transcriptional regulator of aromatic amino acids metabolism; DNA-binding transcriptional regulator TyrR complement(2812136..2813677) Escherichia coli O104:H4 str. 2009EL-2050 13689193 YP_006770379.1 CDS O3M_13695 NC_018650.1 2813825 2814886 R COG3768 Predicted membrane protein; hypothetical protein complement(2813825..2814886) Escherichia coli O104:H4 str. 2009EL-2050 13689194 YP_006770380.1 CDS O3M_13700 NC_018650.1 2814883 2816280 R COG3106 Predicted ATPase; hypothetical protein complement(2814883..2816280) Escherichia coli O104:H4 str. 2009EL-2050 13689195 YP_006770381.1 CDS O3M_13705 NC_018650.1 2816435 2817433 D COG1609 Transcriptional regulators; DNA-binding transcriptional regulator 2816435..2817433 Escherichia coli O104:H4 str. 2009EL-2050 13689196 YP_006770382.1 CDS O3M_13710 NC_018650.1 2817544 2818449 R outer membrane porin complement(2817544..2818449) Escherichia coli O104:H4 str. 2009EL-2050 13689197 YP_006770383.1 CDS O3M_13715 NC_018650.1 2818494 2819576 R COG3839 ABC-type sugar transport systems, ATPase components; sugar transporter subunit complement(2818494..2819576) Escherichia coli O104:H4 str. 2009EL-2050 13689198 YP_006770384.1 CDS O3M_13720 NC_018650.1 2819590 2820249 R COG0637 Predicted phosphatase/phosphohexomutase; beta-phosphoglucomutase complement(2819590..2820249) Escherichia coli O104:H4 str. 2009EL-2050 13689199 YP_006770385.1 CDS O3M_13725 NC_018650.1 2820246 2822513 R COG1554 Trehalose and maltose hydrolases (possible phosphorylases); hydrolase complement(2820246..2822513) Escherichia coli O104:H4 str. 2009EL-2050 13689200 YP_006770386.1 CDS O3M_13730 NC_018650.1 2822510 2823565 R COG0673 Predicted dehydrogenases and related proteins; oxidoreductase complement(2822510..2823565) Escherichia coli O104:H4 str. 2009EL-2050 13689201 YP_006770387.1 CDS O3M_13735 NC_018650.1 2823575 2824363 R COG1082 Sugar phosphate isomerases/epimerases; hypothetical protein complement(2823575..2824363) Escherichia coli O104:H4 str. 2009EL-2050 13689202 YP_006770388.1 CDS O3M_13740 NC_018650.1 2824381 2825433 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein complement(2824381..2825433) Escherichia coli O104:H4 str. 2009EL-2050 13689203 YP_006770389.1 CDS O3M_13745 NC_018650.1 2825464 2826306 R COG0395 ABC-type sugar transport system, permease component; sugar transporter subunit complement(2825464..2826306) Escherichia coli O104:H4 str. 2009EL-2050 13689204 YP_006770390.1 CDS O3M_13750 NC_018650.1 2826293 2827174 R COG1175 ABC-type sugar transport systems, permease components; sugar transporter subunit complement(2826293..2827174) Escherichia coli O104:H4 str. 2009EL-2050 13689205 YP_006770391.1 CDS O3M_13755 NC_018650.1 2827195 2828487 R COG1653 ABC-type sugar transport system, periplasmic component; sugar transporter subunit complement(2827195..2828487) Escherichia coli O104:H4 str. 2009EL-2050 13689206 YP_006770392.1 CDS O3M_13760 NC_018650.1 2828501 2830180 R COG0366 Glycosidases; glucosyltransferase complement(2828501..2830180) Escherichia coli O104:H4 str. 2009EL-2050 13689207 YP_006770393.1 CDS O3M_13765 NC_018650.1 2830393 2830707 R COG0607 Rhodanese-related sulfurtransferase; thiosulfate:cyanide sulfurtransferase complement(2830393..2830707) Escherichia coli O104:H4 str. 2009EL-2050 13689208 YP_006770394.1 CDS O3M_13770 NC_018650.1 2830782 2831003 R peripheral inner membrane phage-shock protein complement(2830782..2831003) Escherichia coli O104:H4 str. 2009EL-2050 13689209 YP_006770395.1 CDS O3M_13775 NC_018650.1 2831012 2831371 R COG1983 Putative stress-responsive transcriptional regulator; DNA-binding transcriptional activator PspC complement(2831012..2831371) Escherichia coli O104:H4 str. 2009EL-2050 13689210 YP_006770396.1 CDS pspB NC_018650.1 2831371 2831595 R phage shock protein B complement(2831371..2831595) Escherichia coli O104:H4 str. 2009EL-2050 13689211 YP_006770397.1 CDS O3M_13785 NC_018650.1 2831649 2832317 R COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription; phage shock protein PspA complement(2831649..2832317) Escherichia coli O104:H4 str. 2009EL-2050 13689212 YP_006770398.1 CDS pspF NC_018650.1 2832484 2833461 D COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain; phage shock protein operon transcriptional activator 2832484..2833461 Escherichia coli O104:H4 str. 2009EL-2050 13689213 YP_006770399.1 CDS O3M_13795 NC_018650.1 2833581 2834846 R COG0160 4-aminobutyrate aminotransferase and related aminotransferases; 4-aminobutyrate transaminase complement(2833581..2834846) Escherichia coli O104:H4 str. 2009EL-2050 13689214 YP_006770400.1 CDS O3M_13800 NC_018650.1 2834884 2836164 R COG0665 Glycine/D-amino acid oxidases (deaminating); gamma-Glu-putrescine oxidase complement(2834884..2836164) Escherichia coli O104:H4 str. 2009EL-2050 13689215 YP_006770401.1 CDS O3M_13805 NC_018650.1 2836166 2837653 R COG1012 NAD-dependent aldehyde dehydrogenases; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase complement(2836166..2837653) Escherichia coli O104:H4 str. 2009EL-2050 13689216 YP_006770402.1 CDS O3M_13810 NC_018650.1 2837928 2838485 R COG1396 Predicted transcriptional regulators; DNA-binding transcriptional repressor PuuR complement(2837928..2838485) Escherichia coli O104:H4 str. 2009EL-2050 13689217 YP_006770403.1 CDS puuD NC_018650.1 2838512 2839276 R COG2071 Predicted glutamine amidotransferases; gamma-glutamyl-gamma-aminobutyrate hydrolase complement(2838512..2839276) Escherichia coli O104:H4 str. 2009EL-2050 13689218 YP_006770404.1 CDS O3M_13820 NC_018650.1 2839488 2840906 D COG0174 Glutamine synthetase; gamma-glutamylputrescine synthetase 2839488..2840906 Escherichia coli O104:H4 str. 2009EL-2050 13689219 YP_006770405.1 CDS O3M_13825 NC_018650.1 2841209 2842594 D COG0531 Amino acid transporters; putrescine importer 2841209..2842594 Escherichia coli O104:H4 str. 2009EL-2050 13689220 YP_006770406.1 CDS O3M_13830 NC_018650.1 2842728 2842973 D hypothetical protein 2842728..2842973 Escherichia coli O104:H4 str. 2009EL-2050 13689221 YP_006770407.1 CDS O3M_13835 NC_018650.1 2843285 2844928 D COG4166 ABC-type oligopeptide transport system, periplasmic component; antimicrobial peptide ABC transporter substrate-binding protein SapA 2843285..2844928 Escherichia coli O104:H4 str. 2009EL-2050 13689222 YP_006770408.1 CDS O3M_13840 NC_018650.1 2844925 2845890 D COG4168 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease SapB 2844925..2845890 Escherichia coli O104:H4 str. 2009EL-2050 13689223 YP_006770409.1 CDS O3M_13845 NC_018650.1 2845877 2846767 D COG4171 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease SapC 2845877..2846767 Escherichia coli O104:H4 str. 2009EL-2050 13689224 YP_006770410.1 CDS O3M_13850 NC_018650.1 2846767 2847759 D COG4170 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATP-binding protein 2846767..2847759 Escherichia coli O104:H4 str. 2009EL-2050 13689225 YP_006770411.1 CDS O3M_13855 NC_018650.1 2847761 2848567 D COG4167 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATP-binding protein SapF 2847761..2848567 Escherichia coli O104:H4 str. 2009EL-2050 13689226 YP_006770412.1 CDS O3M_13860 NC_018650.1 2848635 2848988 D COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 2848635..2848988 Escherichia coli O104:H4 str. 2009EL-2050 13689227 YP_006770413.1 CDS O3M_13865 NC_018650.1 2849358 2850146 D COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); enoyl-ACP reductase 2849358..2850146 Escherichia coli O104:H4 str. 2009EL-2050 13689228 YP_006770414.1 CDS O3M_13870 NC_018650.1 2850291 2851418 D COG2128 Uncharacterized conserved protein; oxidoreductase 2850291..2851418 Escherichia coli O104:H4 str. 2009EL-2050 13689229 YP_006770415.1 CDS O3M_13875 NC_018650.1 2851486 2853420 D COG4776 Exoribonuclease II; exoribonuclease II 2851486..2853420 Escherichia coli O104:H4 str. 2009EL-2050 13689230 YP_006770416.1 CDS O3M_13880 NC_018650.1 2853498 2853602 R hypothetical protein complement(2853498..2853602) Escherichia coli O104:H4 str. 2009EL-2050 13689231 YP_006770417.1 CDS O3M_13885 NC_018650.1 2853656 2855641 D COG2199 FOG: GGDEF domain; RNase II stability modulator 2853656..2855641 Escherichia coli O104:H4 str. 2009EL-2050 13689232 YP_006770418.1 CDS O3M_13890 NC_018650.1 2855788 2855961 D hypothetical protein 2855788..2855961 Escherichia coli O104:H4 str. 2009EL-2050 13689233 YP_006770419.1 CDS O3M_13895 NC_018650.1 2856051 2856800 D COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptionel regulator 2856051..2856800 Escherichia coli O104:H4 str. 2009EL-2050 13689234 YP_006770420.1 CDS O3M_13900 NC_018650.1 2857069 2857287 D lipoprotein 2857069..2857287 Escherichia coli O104:H4 str. 2009EL-2050 13689235 YP_006770421.1 CDS O3M_13905 NC_018650.1 2857413 2857739 R COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins; translation initiation factor Sui1 complement(2857413..2857739) Escherichia coli O104:H4 str. 2009EL-2050 13689236 YP_006770422.1 CDS O3M_13910 NC_018650.1 2857739 2858476 R COG0284 Orotidine-5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase complement(2857739..2858476) Escherichia coli O104:H4 str. 2009EL-2050 13689237 YP_006770423.1 CDS O3M_13915 NC_018650.1 2858669 2859838 R COG2956 Predicted N-acetylglucosaminyl transferase; hypothetical protein complement(2858669..2859838) Escherichia coli O104:H4 str. 2009EL-2050 13689238 YP_006770424.1 CDS O3M_13920 NC_018650.1 2859845 2860153 R COG3771 Predicted membrane protein; hypothetical protein complement(2859845..2860153) Escherichia coli O104:H4 str. 2009EL-2050 13689239 YP_006770425.1 CDS O3M_13925 NC_018650.1 2860302 2861066 R COG0671 Membrane-associated phospholipid phosphatase; phosphatidylglycerophosphatase B complement(2860302..2861066) Escherichia coli O104:H4 str. 2009EL-2050 13689240 YP_006770426.1 CDS ribA NC_018650.1 2861236 2861826 D COG0807 GTP cyclohydrolase II; GTP cyclohydrolase II 2861236..2861826 Escherichia coli O104:H4 str. 2009EL-2050 13689241 YP_006770427.1 CDS O3M_13935 NC_018650.1 2861890 2864565 R COG1048 Aconitase A; aconitate hydratase complement(2861890..2864565) Escherichia coli O104:H4 str. 2009EL-2050 13689242 YP_006770428.1 CDS O3M_13940 NC_018650.1 2864739 2864864 D hypothetical protein 2864739..2864864 Escherichia coli O104:H4 str. 2009EL-2050 13689243 YP_006770429.1 CDS O3M_13945 NC_018650.1 2864938 2865105 R hypothetical protein complement(2864938..2865105) Escherichia coli O104:H4 str. 2009EL-2050 13689244 YP_006770430.1 CDS O3M_13950 NC_018650.1 2865108 2865236 R hypothetical protein complement(2865108..2865236) Escherichia coli O104:H4 str. 2009EL-2050 13689245 YP_006770431.1 CDS cysB NC_018650.1 2865566 2866540 R COG0583 Transcriptional regulator; transcriptional regulator CysB complement(2865566..2866540) Escherichia coli O104:H4 str. 2009EL-2050 13689246 YP_006770432.1 CDS O3M_13960 NC_018650.1 2866750 2869347 R COG0550 Topoisomerase IA; DNA topoisomerase I subunit omega complement(2866750..2869347) Escherichia coli O104:H4 str. 2009EL-2050 13689247 YP_006770433.1 CDS O3M_13965 NC_018650.1 2869727 2869978 D hypothetical protein 2869727..2869978 Escherichia coli O104:H4 str. 2009EL-2050 13689248 YP_006770434.1 CDS O3M_13970 NC_018650.1 2870014 2871063 R COG0616 Periplasmic serine proteases (ClpP class); inner membrane peptidase complement(2870014..2871063) Escherichia coli O104:H4 str. 2009EL-2050 13689249 YP_006770435.1 CDS O3M_13975 NC_018650.1 2871283 2872041 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxoacyl-(acyl carrier protein) reductase 2871283..2872041 Escherichia coli O104:H4 str. 2009EL-2050 13689250 YP_006770436.1 CDS O3M_13980 NC_018650.1 2872038 2872628 D COG2109 ATP:corrinoid adenosyltransferase; cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase 2872038..2872628 Escherichia coli O104:H4 str. 2009EL-2050 13689251 YP_006770437.1 CDS O3M_13985 NC_018650.1 2872668 2873540 R COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridylate synthase B complement(2872668..2873540) Escherichia coli O104:H4 str. 2009EL-2050 13689252 YP_006770438.1 CDS O3M_13990 NC_018650.1 2873641 2874261 R COG0009 Putative translation factor (SUA5); hypothetical protein complement(2873641..2874261) Escherichia coli O104:H4 str. 2009EL-2050 13689253 YP_006770439.1 CDS O3M_13995 NC_018650.1 2874258 2875139 R COG0613 Predicted metal-dependent phosphoesterases (PHP family); hypothetical protein complement(2874258..2875139) Escherichia coli O104:H4 str. 2009EL-2050 13689254 YP_006770440.1 CDS O3M_14000 NC_018650.1 2875413 2876975 D COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate synthase component I 2875413..2876975 Escherichia coli O104:H4 str. 2009EL-2050 13689255 YP_006770441.1 CDS O3M_14005 NC_018650.1 2876975 2878570 D COG0512 Anthranilate/para-aminobenzoate synthases component II; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 2876975..2878570 Escherichia coli O104:H4 str. 2009EL-2050 13689256 YP_006770442.1 CDS O3M_14010 NC_018650.1 2878574 2879932 D COG0134 Indole-3-glycerol phosphate synthase; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 2878574..2879932 Escherichia coli O104:H4 str. 2009EL-2050 13689257 YP_006770443.1 CDS O3M_14015 NC_018650.1 2879944 2881137 D COG0133 Tryptophan synthase beta chain; tryptophan synthase subunit beta 2879944..2881137 Escherichia coli O104:H4 str. 2009EL-2050 13689258 YP_006770444.1 CDS trpA NC_018650.1 2881137 2881943 D COG0159 Tryptophan synthase alpha chain; tryptophan synthase subunit alpha 2881137..2881943 Escherichia coli O104:H4 str. 2009EL-2050 13689259 YP_006770445.1 CDS O3M_14025 NC_018650.1 2882589 2883089 D COG3685 Uncharacterized protein conserved in bacteria; YciF protein 2882589..2883089 Escherichia coli O104:H4 str. 2009EL-2050 13689260 YP_006770446.1 CDS O3M_14030 NC_018650.1 2883135 2883641 D COG3685 Uncharacterized protein conserved in bacteria; hypothetical protein 2883135..2883641 Escherichia coli O104:H4 str. 2009EL-2050 13689261 YP_006770447.1 CDS O3M_14035 NC_018650.1 2884130 2884300 R tail component complement(2884130..2884300) Escherichia coli O104:H4 str. 2009EL-2050 13689262 YP_006770448.1 CDS O3M_14040 NC_018650.1 2884415 2884684 R tail fiber assembly protein complement(2884415..2884684) Escherichia coli O104:H4 str. 2009EL-2050 13689263 YP_006770449.1 CDS O3M_14045 NC_018650.1 2884753 2885409 D COG0500 SAM-dependent methyltransferases; hypothetical protein 2884753..2885409 Escherichia coli O104:H4 str. 2009EL-2050 13689264 YP_006770450.1 CDS O3M_14050 NC_018650.1 2885464 2886048 R Qin prophage; tail fiber chaperone complement(2885464..2886048) Escherichia coli O104:H4 str. 2009EL-2050 13689265 YP_006770451.1 CDS O3M_14055 NC_018650.1 2886048 2888882 R phage tail fiber protein complement(2886048..2888882) Escherichia coli O104:H4 str. 2009EL-2050 13689266 YP_006770452.1 CDS O3M_14060 NC_018650.1 2889034 2889633 R outer membrane Lom complement(2889034..2889633) Escherichia coli O104:H4 str. 2009EL-2050 13689267 YP_006770453.1 CDS O3M_14065 NC_018650.1 2889701 2893180 R COG4733 Phage-related protein, tail component; Host specificity protein J complement(2889701..2893180) Escherichia coli O104:H4 str. 2009EL-2050 13689268 YP_006770454.1 CDS O3M_14070 NC_018650.1 2893659 2894300 R COG4723 Phage-related protein, tail component; Tail assembly protein I from prophage complement(2893659..2894300) Escherichia coli O104:H4 str. 2009EL-2050 13689269 YP_006770455.1 CDS O3M_14075 NC_018650.1 2894198 2894941 R COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; tail fiber component K of prophage complement(2894198..2894941) Escherichia coli O104:H4 str. 2009EL-2050 13689270 YP_006770456.1 CDS O3M_14080 NC_018650.1 2894946 2895644 R COG4672 Phage-related protein; minor tail protein L complement(2894946..2895644) Escherichia coli O104:H4 str. 2009EL-2050 13689271 YP_006770457.1 CDS O3M_14085 NC_018650.1 2895644 2895973 R COG4718 Phage-related protein; minor tail protein M complement(2895644..2895973) Escherichia coli O104:H4 str. 2009EL-2050 13689272 YP_006770458.1 CDS O3M_14090 NC_018650.1 2895970 2898543 R COG5281 Phage-related minor tail protein; minor tail protein H complement(2895970..2898543) Escherichia coli O104:H4 str. 2009EL-2050 13689273 YP_006770459.1 CDS O3M_14095 NC_018650.1 2898524 2898937 R tail protein complement(2898524..2898937) Escherichia coli O104:H4 str. 2009EL-2050 13689274 YP_006770460.1 CDS O3M_14100 NC_018650.1 2898964 2899395 R minor tail protein G complement(2898964..2899395) Escherichia coli O104:H4 str. 2009EL-2050 13689275 YP_006770461.1 CDS O3M_14105 NC_018650.1 2899409 2900161 R COG5492 Bacterial surface proteins containing Ig-like domains; major tail protein V complement(2899409..2900161) Escherichia coli O104:H4 str. 2009EL-2050 13689276 YP_006770462.1 CDS O3M_14110 NC_018650.1 2900169 2900564 R minor tail protein complement(2900169..2900564) Escherichia coli O104:H4 str. 2009EL-2050 13689277 YP_006770463.1 CDS O3M_14115 NC_018650.1 2900561 2901136 R minor tail protein Z (GpZ) complement(2900561..2901136) Escherichia coli O104:H4 str. 2009EL-2050 13689278 YP_006770464.1 CDS O3M_14120 NC_018650.1 2901151 2901504 R Tail attachment protein (Minor capsid protein FII) complement(2901151..2901504) Escherichia coli O104:H4 str. 2009EL-2050 13689279 YP_006770465.1 CDS O3M_14125 NC_018650.1 2901497 2901865 R DNA packaging protein from phage origin complement(2901497..2901865) Escherichia coli O104:H4 str. 2009EL-2050 13689280 YP_006770466.1 CDS O3M_14130 NC_018650.1 2901917 2902945 R major head protein complement(2901917..2902945) Escherichia coli O104:H4 str. 2009EL-2050 13689281 YP_006770467.1 CDS O3M_14135 NC_018650.1 2903003 2903350 R head-DNA stabilization protein complement(2903003..2903350) Escherichia coli O104:H4 str. 2009EL-2050 13689282 YP_006770468.1 CDS O3M_14140 NC_018650.1 2903387 2904892 R COG0616 Periplasmic serine proteases (ClpP class); Head-tail preconnector protein GP5 (Contains: Scaffold protein GP6 (Head protein GP6)) complement(2903387..2904892) Escherichia coli O104:H4 str. 2009EL-2050 13689283 YP_006770469.1 CDS O3M_14145 NC_018650.1 2904882 2906474 R COG5511 Bacteriophage capsid protein; portal protein complement(2904882..2906474) Escherichia coli O104:H4 str. 2009EL-2050 13689284 YP_006770470.1 CDS O3M_14150 NC_018650.1 2906471 2906677 R head completion protein complement(2906471..2906677) Escherichia coli O104:H4 str. 2009EL-2050 13689285 YP_006770471.1 CDS O3M_14155 NC_018650.1 2906661 2907059 R COG5525 Bacteriophage tail assembly protein; terminase large subunit (Gp2) complement(2906661..2907059) Escherichia coli O104:H4 str. 2009EL-2050 13689286 YP_006770472.1 CDS O3M_14160 NC_018650.1 2907046 2908590 R COG5525 Bacteriophage tail assembly protein; Terminase large subunit (Gp2) complement(2907046..2908590) Escherichia coli O104:H4 str. 2009EL-2050 13689287 YP_006770473.1 CDS O3M_14165 NC_018650.1 2908562 2909110 R COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; prophage Qin DNA packaging protein NU1-like protein complement(2908562..2909110) Escherichia coli O104:H4 str. 2009EL-2050 13689288 YP_006770474.1 CDS O3M_14170 NC_018650.1 2909192 2909464 R hypothetical protein complement(2909192..2909464) Escherichia coli O104:H4 str. 2009EL-2050 13689289 YP_006770475.1 CDS O3M_14175 NC_018650.1 2909511 2909915 R hypothetical protein complement(2909511..2909915) Escherichia coli O104:H4 str. 2009EL-2050 13689290 YP_006770476.1 CDS O3M_14180 NC_018650.1 2910051 2910275 R hypothetical protein complement(2910051..2910275) Escherichia coli O104:H4 str. 2009EL-2050 13689291 YP_006770477.1 CDS O3M_14185 NC_018650.1 2910369 2910656 R hypothetical protein complement(2910369..2910656) Escherichia coli O104:H4 str. 2009EL-2050 13689292 YP_006770478.1 CDS O3M_14190 NC_018650.1 2910735 2910878 R hypothetical protein complement(2910735..2910878) Escherichia coli O104:H4 str. 2009EL-2050 13689293 YP_006770479.1 CDS O3M_14195 NC_018650.1 2910875 2911342 R endopeptidase complement(2910875..2911342) Escherichia coli O104:H4 str. 2009EL-2050 13689294 YP_006770480.1 CDS O3M_14200 NC_018650.1 2911442 2911657 R hypothetical protein complement(2911442..2911657) Escherichia coli O104:H4 str. 2009EL-2050 13689295 YP_006770481.1 CDS O3M_14205 NC_018650.1 2911695 2911907 R COG5178 U5 snRNP spliceosome subunit; hypothetical protein complement(2911695..2911907) Escherichia coli O104:H4 str. 2009EL-2050 13689296 YP_006770482.1 CDS O3M_14210 NC_018650.1 2911985 2912518 R COG3772 Phage-related lysozyme (muraminidase); phage-related lysozyme (muraminidase) complement(2911985..2912518) Escherichia coli O104:H4 str. 2009EL-2050 13689297 YP_006770483.1 CDS O3M_14215 NC_018650.1 2912561 2913367 R phage protein complement(2912561..2913367) Escherichia coli O104:H4 str. 2009EL-2050 13689298 YP_006770484.1 CDS O3M_14220 NC_018650.1 2913372 2913587 R lysis protein S of prophage CP-933V complement(2913372..2913587) Escherichia coli O104:H4 str. 2009EL-2050 13689299 YP_006770485.1 CDS O3M_14225 NC_018650.1 2913738 2915591 R prophage protein complement(2913738..2915591) Escherichia coli O104:H4 str. 2009EL-2050 13689300 YP_006770486.1 CDS O3M_14230 NC_018650.1 2915864 2916187 D anti-adapter protein IraM 2915864..2916187 Escherichia coli O104:H4 str. 2009EL-2050 13689301 YP_006770487.1 CDS O3M_14235 NC_018650.1 2916635 2916913 R hypothetical protein complement(2916635..2916913) Escherichia coli O104:H4 str. 2009EL-2050 13689302 YP_006770488.1 CDS O3M_14240 NC_018650.1 2917398 2918447 R COG0863 DNA modification methylase; DNA adenine methyltransferase ( DNA methylase) from phage origin complement(2917398..2918447) Escherichia coli O104:H4 str. 2009EL-2050 13689306 YP_006770489.1 CDS O3M_14245 NC_018650.1 2918598 2918795 R hypothetical protein complement(2918598..2918795) Escherichia coli O104:H4 str. 2009EL-2050 13689307 YP_006770490.1 CDS O3M_14250 NC_018650.1 2919022 2919843 R COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; antitermination protein Q of prophage complement(2919022..2919843) Escherichia coli O104:H4 str. 2009EL-2050 13689308 YP_006770491.1 CDS O3M_14255 NC_018650.1 2919840 2920214 R COG4570 Holliday junction resolvase; holliday junction resolvase complement(2919840..2920214) Escherichia coli O104:H4 str. 2009EL-2050 13689309 YP_006770492.1 CDS O3M_14260 NC_018650.1 2920227 2921273 R hypothetical protein complement(2920227..2921273) Escherichia coli O104:H4 str. 2009EL-2050 13689310 YP_006770493.1 CDS O3M_14265 NC_018650.1 2921494 2921673 D hypothetical protein 2921494..2921673 Escherichia coli O104:H4 str. 2009EL-2050 13689311 YP_006770494.1 CDS O3M_14270 NC_018650.1 2921715 2921927 R cell killing protein encoded within cryptic prophage CP-933M complement(2921715..2921927) Escherichia coli O104:H4 str. 2009EL-2050 13689312 YP_006770495.1 CDS O3M_14275 NC_018650.1 2922108 2922794 R COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2922108..2922794) Escherichia coli O104:H4 str. 2009EL-2050 13689313 YP_006770496.1 CDS O3M_14280 NC_018650.1 2922948 2923373 R phage protein complement(2922948..2923373) Escherichia coli O104:H4 str. 2009EL-2050 13689314 YP_006770497.1 CDS O3M_14285 NC_018650.1 2923414 2924376 R replication protein complement(2923414..2924376) Escherichia coli O104:H4 str. 2009EL-2050 13689315 YP_006770498.1 CDS O3M_14290 NC_018650.1 2924399 2924824 R phage regulatory protein CII complement(2924399..2924824) Escherichia coli O104:H4 str. 2009EL-2050 13689316 YP_006770499.1 CDS O3M_14295 NC_018650.1 2924821 2925075 R regulatory protein complement(2924821..2925075) Escherichia coli O104:H4 str. 2009EL-2050 13689317 YP_006770500.1 CDS O3M_14300 NC_018650.1 2925155 2925574 D COG1396 Predicted transcriptional regulators; phage repressor protein CI 2925155..2925574 Escherichia coli O104:H4 str. 2009EL-2050 13689318 YP_006770501.1 CDS O3M_14305 NC_018650.1 2925871 2926023 D hypothetical protein 2925871..2926023 Escherichia coli O104:H4 str. 2009EL-2050 13689319 YP_006770502.1 CDS O3M_14310 NC_018650.1 2926035 2926373 D hypothetical protein 2926035..2926373 Escherichia coli O104:H4 str. 2009EL-2050 13689320 YP_006770503.1 CDS O3M_14315 NC_018650.1 2926362 2926556 R hypothetical protein complement(2926362..2926556) Escherichia coli O104:H4 str. 2009EL-2050 13689321 YP_006770504.1 CDS O3M_14320 NC_018650.1 2927123 2927311 D regulator of cell division encoded by prophage 2927123..2927311 Escherichia coli O104:H4 str. 2009EL-2050 13689322 YP_006770505.1 CDS O3M_14325 NC_018650.1 2927308 2927499 D hypothetical protein 2927308..2927499 Escherichia coli O104:H4 str. 2009EL-2050 13689323 YP_006770506.1 CDS O3M_14330 NC_018650.1 2927592 2930063 D exonuclease from phage origin 2927592..2930063 Escherichia coli O104:H4 str. 2009EL-2050 13689324 YP_006770507.1 CDS O3M_14335 NC_018650.1 2930128 2930376 D excisionase 2930128..2930376 Escherichia coli O104:H4 str. 2009EL-2050 13689325 YP_006770508.1 CDS O3M_14340 NC_018650.1 2930354 2931484 D COG0582 Integrase; integrase 2930354..2931484 Escherichia coli O104:H4 str. 2009EL-2050 13689326 YP_006770509.1 CDS O3M_14345 NC_018650.1 2931530 2932168 R COG3047 Outer membrane protein W; outer membrane protein W complement(2931530..2932168) Escherichia coli O104:H4 str. 2009EL-2050 13689327 YP_006770510.1 CDS O3M_14350 NC_018650.1 2932525 2933268 D hypothetical protein 2932525..2933268 Escherichia coli O104:H4 str. 2009EL-2050 13689328 YP_006770511.1 CDS O3M_14355 NC_018650.1 2933298 2933837 D COG2917 Intracellular septation protein A; intracellular septation protein A 2933298..2933837 Escherichia coli O104:H4 str. 2009EL-2050 13689329 YP_006770512.1 CDS O3M_14360 NC_018650.1 2933942 2934340 D COG1607 Acyl-CoA hydrolase; acyl-CoA esterase 2933942..2934340 Escherichia coli O104:H4 str. 2009EL-2050 13689330 YP_006770513.1 CDS O3M_14365 NC_018650.1 2934380 2935099 R COG0810 Periplasmic protein TonB, links inner and outer membranes; transporter complement(2934380..2935099) Escherichia coli O104:H4 str. 2009EL-2050 13689331 YP_006770514.1 CDS O3M_14370 NC_018650.1 2935323 2935619 D COG2350 Uncharacterized protein conserved in bacteria; YciI-like protein 2935323..2935619 Escherichia coli O104:H4 str. 2009EL-2050 13689332 YP_006770515.1 CDS O3M_14375 NC_018650.1 2935919 2937172 D COG1226 Kef-type K+ transport systems, predicted NAD-binding component; voltage-gated potassium channel 2935919..2937172 Escherichia coli O104:H4 str. 2009EL-2050 13689333 YP_006770516.1 CDS cls NC_018650.1 2937543 2939003 D COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; cardiolipin synthetase 2937543..2939003 Escherichia coli O104:H4 str. 2009EL-2050 13689334 YP_006770517.1 CDS O3M_14385 NC_018650.1 2939038 2939367 D COG3099 Uncharacterized protein conserved in bacteria; dsDNA-mimic protein 2939038..2939367 Escherichia coli O104:H4 str. 2009EL-2050 13689335 YP_006770518.1 CDS O3M_14390 NC_018650.1 2939420 2940424 R COG4608 ABC-type oligopeptide transport system, ATPase component; oligopeptide ABC transporter ATP-binding protein OppF complement(2939420..2940424) Escherichia coli O104:H4 str. 2009EL-2050 13689336 YP_006770519.1 CDS oppD NC_018650.1 2940421 2941434 R COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; oligopeptide ABC transporter ATP-binding protein complement(2940421..2941434) Escherichia coli O104:H4 str. 2009EL-2050 13689337 YP_006770520.1 CDS O3M_14400 NC_018650.1 2941446 2942354 R COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; oligopeptide ABC transporter permease OppC complement(2941446..2942354) Escherichia coli O104:H4 str. 2009EL-2050 13689338 YP_006770521.1 CDS oppB NC_018650.1 2942369 2943289 R COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; oligopeptide transporter permease complement(2942369..2943289) Escherichia coli O104:H4 str. 2009EL-2050 13689339 YP_006770522.1 CDS O3M_14410 NC_018650.1 2943375 2945006 R COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein OppA complement(2943375..2945006) Escherichia coli O104:H4 str. 2009EL-2050 13689340 YP_006770523.1 CDS O3M_14415 NC_018650.1 2945744 2946391 R COG2095 Multiple antibiotic transporter; hypothetical protein complement(2945744..2946391) Escherichia coli O104:H4 str. 2009EL-2050 13689341 YP_006770524.1 CDS O3M_14420 NC_018650.1 2946868 2949543 D COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2946868..2949543 Escherichia coli O104:H4 str. 2009EL-2050 13689342 YP_006770525.1 CDS O3M_14440 NC_018650.1 2950849 2951466 R COG1435 Thymidine kinase; thymidine kinase complement(2950849..2951466) Escherichia coli O104:H4 str. 2009EL-2050 13689343 YP_006770526.1 CDS O3M_14445 NC_018650.1 2952072 2952485 D COG2916 DNA-binding protein H-NS; global DNA-binding transcriptional dual regulator H-NS 2952072..2952485 Escherichia coli O104:H4 str. 2009EL-2050 13689344 YP_006770527.1 CDS O3M_14450 NC_018650.1 2952629 2953537 R COG1210 UDP-glucose pyrophosphorylase; UTP--glucose-1-phosphate uridylyltransferase subunit GalU complement(2952629..2953537) Escherichia coli O104:H4 str. 2009EL-2050 13689345 YP_006770528.1 CDS O3M_14455 NC_018650.1 2953739 2954752 R COG0784 FOG: CheY-like receiver; response regulator of RpoS complement(2953739..2954752) Escherichia coli O104:H4 str. 2009EL-2050 13689346 YP_006770529.1 CDS O3M_14460 NC_018650.1 2954844 2955749 R COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein complement(2954844..2955749) Escherichia coli O104:H4 str. 2009EL-2050 13689347 YP_006770530.1 CDS O3M_14465 NC_018650.1 2955862 2956320 D COG3012 Uncharacterized protein conserved in bacteria; hypothetical protein 2955862..2956320 Escherichia coli O104:H4 str. 2009EL-2050 13689348 YP_006770531.1 CDS purU NC_018650.1 2956370 2957212 D COG0788 Formyltetrahydrofolate hydrolase; formyltetrahydrofolate deformylase 2956370..2957212 Escherichia coli O104:H4 str. 2009EL-2050 13689349 YP_006770532.1 CDS O3M_14485 NC_018650.1 2957937 2958614 R COG2181 Nitrate reductase gamma subunit; Respiratory nitrate reductase subunit gamma complement(2957937..2958614) Escherichia coli O104:H4 str. 2009EL-2050 13689352 YP_006770533.1 CDS O3M_14490 NC_018650.1 2958614 2959324 R COG2180 Nitrate reductase delta subunit; molybdenum-cofactor-assembly chaperone subunit delta complement(2958614..2959324) Escherichia coli O104:H4 str. 2009EL-2050 13689353 YP_006770534.1 CDS O3M_14495 NC_018650.1 2959321 2960859 R COG1140 Nitrate reductase beta subunit; nitrate reductase subunit beta complement(2959321..2960859) Escherichia coli O104:H4 str. 2009EL-2050 13689354 YP_006770535.1 CDS O3M_14500 NC_018650.1 2960856 2964599 R COG5013 Nitrate reductase alpha subunit; nitrate reductase subunit alpha complement(2960856..2964599) Escherichia coli O104:H4 str. 2009EL-2050 13689355 YP_006770536.1 CDS O3M_14505 NC_018650.1 2965115 2966506 R COG2223 Nitrate/nitrite transporter; nitrite extrusion protein complement(2965115..2966506) Escherichia coli O104:H4 str. 2009EL-2050 13689356 YP_006770537.1 CDS O3M_14510 NC_018650.1 2966845 2968641 D COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific; nitrate/nitrite sensor protein NarX 2966845..2968641 Escherichia coli O104:H4 str. 2009EL-2050 13689357 YP_006770538.1 CDS O3M_14515 NC_018650.1 2968634 2969284 D two-component regulatory system; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding response regulator NarL/sensory histidine kinase NarX 2968634..2969284 Escherichia coli O104:H4 str. 2009EL-2050 13689358 YP_006770539.1 CDS O3M_14520 NC_018650.1 2969285 2970538 R invasin complement(2969285..2970538) Escherichia coli O104:H4 str. 2009EL-2050 13689359 YP_006770540.1 CDS O3M_14525 NC_018650.1 2970864 2971217 D COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction; hypothetical protein 2970864..2971217 Escherichia coli O104:H4 str. 2009EL-2050 13689360 YP_006770541.1 CDS O3M_14530 NC_018650.1 2971261 2971977 R COG3703 Uncharacterized protein involved in cation transport; regulatory protein for cation transport complement(2971261..2971977) Escherichia coli O104:H4 str. 2009EL-2050 13689361 YP_006770542.1 CDS chaB NC_018650.1 2972114 2972344 R COG4572 Putative cation transport regulator; cation transport regulator complement(2972114..2972344) Escherichia coli O104:H4 str. 2009EL-2050 13689362 YP_006770543.1 CDS O3M_14540 NC_018650.1 2972614 2973714 D COG0387 Ca2+/H+ antiporter; calcium/sodium:proton antiporter 2972614..2973714 Escherichia coli O104:H4 str. 2009EL-2050 13689363 YP_006770544.1 CDS O3M_14545 NC_018650.1 2974119 2974226 D hypothetical protein 2974119..2974226 Escherichia coli O104:H4 str. 2009EL-2050 13689364 YP_006770545.1 CDS O3M_14550 NC_018650.1 2974654 2974761 D hypothetical protein 2974654..2974761 Escherichia coli O104:H4 str. 2009EL-2050 13689365 YP_006770546.1 CDS O3M_14555 NC_018650.1 2974910 2975764 R COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; 2-dehydro-3-deoxyphosphooctonate aldolase complement(2974910..2975764) Escherichia coli O104:H4 str. 2009EL-2050 13689366 YP_006770547.1 CDS O3M_14560 NC_018650.1 2975800 2976609 R COG2912 Uncharacterized conserved protein; hypothetical protein complement(2975800..2976609) Escherichia coli O104:H4 str. 2009EL-2050 13689367 YP_006770548.1 CDS O3M_14565 NC_018650.1 2976613 2977005 R COG3094 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2976613..2977005) Escherichia coli O104:H4 str. 2009EL-2050 13689368 YP_006770549.1 CDS O3M_14570 NC_018650.1 2977002 2977835 R COG2890 Methylase of polypeptide chain release factors; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2977002..2977835) Escherichia coli O104:H4 str. 2009EL-2050 13689369 YP_006770550.1 CDS prfA NC_018650.1 2977835 2978917 R COG0216 Protein chain release factor A; peptide chain release factor 1 complement(2977835..2978917) Escherichia coli O104:H4 str. 2009EL-2050 13689370 YP_006770551.1 CDS hemA NC_018650.1 2978959 2980215 R COG0373 Glutamyl-tRNA reductase; glutamyl-tRNA reductase complement(2978959..2980215) Escherichia coli O104:H4 str. 2009EL-2050 13689371 YP_006770552.1 CDS lolB NC_018650.1 2980429 2981052 D COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis; outer membrane lipoprotein LolB 2980429..2981052 Escherichia coli O104:H4 str. 2009EL-2050 13689372 YP_006770553.1 CDS ipk NC_018650.1 2981052 2981903 D COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2981052..2981903 Escherichia coli O104:H4 str. 2009EL-2050 13689373 YP_006770554.1 CDS O3M_14595 NC_018650.1 2982054 2983001 D COG0462 Phosphoribosylpyrophosphate synthetase; ribose-phosphate pyrophosphokinase 2982054..2983001 Escherichia coli O104:H4 str. 2009EL-2050 13689374 YP_006770555.1 CDS O3M_14600 NC_018650.1 2983126 2984805 D COG0659 Sulfate permease and related transporters (MFS superfamily); transporter 2983126..2984805 Escherichia coli O104:H4 str. 2009EL-2050 13689375 YP_006770556.1 CDS O3M_14605 NC_018650.1 2984860 2985138 R hypothetical protein complement(2984860..2985138) Escherichia coli O104:H4 str. 2009EL-2050 13689376 YP_006770557.1 CDS O3M_14610 NC_018650.1 2985416 2986000 D COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 2985416..2986000 Escherichia coli O104:H4 str. 2009EL-2050 13689377 YP_006770558.1 CDS O3M_14615 NC_018650.1 2986117 2987208 D COG0012 Predicted GTPase, probable translation factor; GTP-binding protein YchF 2986117..2987208 Escherichia coli O104:H4 str. 2009EL-2050 13689378 YP_006770559.1 CDS O3M_14620 NC_018650.1 2987453 2987632 R hypothetical protein complement(2987453..2987632) Escherichia coli O104:H4 str. 2009EL-2050 13689379 YP_006770560.1 CDS O3M_14625 NC_018650.1 2987977 2990844 D autotransporter; COG3468 Type V secretory pathway, adhesin AidA; adhesin 2987977..2990844 Escherichia coli O104:H4 str. 2009EL-2050 13689380 YP_006770561.1 CDS O3M_14630 NC_018650.1 2990944 2992863 R COG3284 Transcriptional activator of acetoin/glycerol metabolism; DNA-binding transcriptional regulator DhaR complement(2990944..2992863) Escherichia coli O104:H4 str. 2009EL-2050 13689381 YP_006770562.1 CDS O3M_14635 NC_018650.1 2993091 2994161 D COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 2993091..2994161 Escherichia coli O104:H4 str. 2009EL-2050 13689382 YP_006770563.1 CDS O3M_14640 NC_018650.1 2994172 2994804 D COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaL 2994172..2994804 Escherichia coli O104:H4 str. 2009EL-2050 13689383 YP_006770564.1 CDS O3M_14645 NC_018650.1 2994815 2996233 D COG3412 Uncharacterized protein conserved in bacteria; dihydroxyacetone kinase subunit DhaM 2994815..2996233 Escherichia coli O104:H4 str. 2009EL-2050 13689384 YP_006770565.1 CDS treA NC_018650.1 2996553 2998250 D COG1626 Neutral trehalase; trehalase 2996553..2998250 Escherichia coli O104:H4 str. 2009EL-2050 13689385 YP_006770566.1 CDS O3M_14655 NC_018650.1 2998329 2998769 R hypothetical protein complement(2998329..2998769) Escherichia coli O104:H4 str. 2009EL-2050 13689386 YP_006770567.1 CDS O3M_14660 NC_018650.1 2998947 2999201 R COG2261 Predicted membrane protein; inner membrane protein with transglycosylase-associated domain complement(2998947..2999201) Escherichia coli O104:H4 str. 2009EL-2050 13689387 YP_006770568.1 CDS O3M_14665 NC_018650.1 2999402 3000136 D COG5581 Predicted glycosyltransferase; flagellar function protein 2999402..3000136 Escherichia coli O104:H4 str. 2009EL-2050 13689388 YP_006770569.1 CDS emtA NC_018650.1 3000138 3000749 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic murein endotransglycosylase E complement(3000138..3000749) Escherichia coli O104:H4 str. 2009EL-2050 13689389 YP_006770570.1 CDS ldcA NC_018650.1 3000849 3001763 D COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; L,D-carboxypeptidase A 3000849..3001763 Escherichia coli O104:H4 str. 2009EL-2050 13689390 YP_006770571.1 CDS O3M_14680 NC_018650.1 3001858 3003594 D COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain; potassium/proton antiporter 3001858..3003594 Escherichia coli O104:H4 str. 2009EL-2050 13689391 YP_006770572.1 CDS dadX NC_018650.1 3003980 3005050 R COG0787 Alanine racemase; alanine racemase complement(3003980..3005050) Escherichia coli O104:H4 str. 2009EL-2050 13689392 YP_006770573.1 CDS O3M_14690 NC_018650.1 3005060 3006358 R COG0665 Glycine/D-amino acid oxidases (deaminating); D-amino acid dehydrogenase small subunit complement(3005060..3006358) Escherichia coli O104:H4 str. 2009EL-2050 13689393 YP_006770574.1 CDS O3M_14695 NC_018650.1 3006688 3008220 D COG2719 Uncharacterized conserved protein; SpoVR family protein 3006688..3008220 Escherichia coli O104:H4 str. 2009EL-2050 13689394 YP_006770575.1 CDS O3M_14700 NC_018650.1 3008272 3008991 R COG2186 Transcriptional regulators; fatty acid metabolism regulator complement(3008272..3008991) Escherichia coli O104:H4 str. 2009EL-2050 13689395 YP_006770576.1 CDS nhaB NC_018650.1 3009213 3010754 D COG3067 Na+/H+ antiporter; sodium/proton antiporter 3009213..3010754 Escherichia coli O104:H4 str. 2009EL-2050 13689396 YP_006770577.1 CDS O3M_14710 NC_018650.1 3010900 3011430 D COG1495 Disulfide bond formation protein DsbB; disulfide bond formation protein B 3010900..3011430 Escherichia coli O104:H4 str. 2009EL-2050 13689397 YP_006770578.1 CDS umuC NC_018650.1 3011476 3012744 R COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC complement(3011476..3012744) Escherichia coli O104:H4 str. 2009EL-2050 13689398 YP_006770579.1 CDS O3M_14720 NC_018650.1 3012744 3013163 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); DNA polymerase V subunit UmuD complement(3012744..3013163) Escherichia coli O104:H4 str. 2009EL-2050 13689399 YP_006770580.1 CDS hlyE NC_018650.1 3014165 3014446 D hemolysin E 3014165..3014446 Escherichia coli O104:H4 str. 2009EL-2050 13689400 YP_006770581.1 CDS O3M_14740 NC_018650.1 3014653 3015099 R COG2983 Uncharacterized conserved protein; hypothetical protein complement(3014653..3015099) Escherichia coli O104:H4 str. 2009EL-2050 13689401 YP_006770582.1 CDS O3M_14745 NC_018650.1 3015191 3015850 R COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); hypothetical protein complement(3015191..3015850) Escherichia coli O104:H4 str. 2009EL-2050 13689402 YP_006770583.1 CDS O3M_14750 NC_018650.1 3015922 3016248 R COG3100 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3015922..3016248) Escherichia coli O104:H4 str. 2009EL-2050 13689403 YP_006770584.1 CDS O3M_14755 NC_018650.1 3016457 3016858 D hypothetical protein 3016457..3016858 Escherichia coli O104:H4 str. 2009EL-2050 13689404 YP_006770585.1 CDS O3M_14760 NC_018650.1 3016978 3017346 R hypothetical protein complement(3016978..3017346) Escherichia coli O104:H4 str. 2009EL-2050 13689405 YP_006770586.1 CDS minC NC_018650.1 3017866 3018561 D COG0850 Septum formation inhibitor; septum formation inhibitor 3017866..3018561 Escherichia coli O104:H4 str. 2009EL-2050 13689406 YP_006770587.1 CDS O3M_14770 NC_018650.1 3018585 3019397 D COG2894 Septum formation inhibitor-activating ATPase; cell division inhibitor MinD 3018585..3019397 Escherichia coli O104:H4 str. 2009EL-2050 13689407 YP_006770588.1 CDS minE NC_018650.1 3019401 3019667 D COG0851 Septum formation topological specificity factor; cell division topological specificity factor MinE 3019401..3019667 Escherichia coli O104:H4 str. 2009EL-2050 13689408 YP_006770589.1 CDS O3M_14780 NC_018650.1 3020039 3020251 R adhesin complement(3020039..3020251) Escherichia coli O104:H4 str. 2009EL-2050 13689409 YP_006770590.1 CDS O3M_14785 NC_018650.1 3021019 3021303 D hypothetical protein 3021019..3021303 Escherichia coli O104:H4 str. 2009EL-2050 13689410 YP_006770591.1 CDS O3M_14790 NC_018650.1 3021313 3021642 D hypothetical protein 3021313..3021642 Escherichia coli O104:H4 str. 2009EL-2050 13689411 YP_006770592.1 CDS O3M_14795 NC_018650.1 3021699 3024020 R COG3468 Type V secretory pathway, adhesin AidA; autotransporter complement(3021699..3024020) Escherichia coli O104:H4 str. 2009EL-2050 13689412 YP_006770593.1 CDS O3M_14800 NC_018650.1 3024137 3024346 R hypothetical protein complement(3024137..3024346) Escherichia coli O104:H4 str. 2009EL-2050 13689413 YP_006770594.1 CDS O3M_14805 NC_018650.1 3024746 3024964 R hypothetical protein complement(3024746..3024964) Escherichia coli O104:H4 str. 2009EL-2050 13689414 YP_006770595.1 CDS O3M_14810 NC_018650.1 3025096 3026619 R COG2200 FOG: EAL domain; hypothetical protein complement(3025096..3026619) Escherichia coli O104:H4 str. 2009EL-2050 13689415 YP_006770596.1 CDS O3M_14815 NC_018650.1 3026951 3027199 R hypothetical protein complement(3026951..3027199) Escherichia coli O104:H4 str. 2009EL-2050 13689416 YP_006770597.1 CDS O3M_14820 NC_018650.1 3027312 3027578 R hypothetical protein complement(3027312..3027578) Escherichia coli O104:H4 str. 2009EL-2050 13689417 YP_006770598.1 CDS O3M_14825 NC_018650.1 3027607 3027879 R hypothetical protein complement(3027607..3027879) Escherichia coli O104:H4 str. 2009EL-2050 13689418 YP_006770599.1 CDS O3M_14830 NC_018650.1 3027922 3028158 R hypothetical protein complement(3027922..3028158) Escherichia coli O104:H4 str. 2009EL-2050 13689419 YP_006770600.1 CDS O3M_14835 NC_018650.1 3028473 3029684 D blue-light sensing protein using FAD (BLUF); COG2200 FOG: EAL domain; cyclic-di-GMP phosphodiesterase 3028473..3029684 Escherichia coli O104:H4 str. 2009EL-2050 13689420 YP_006770601.1 CDS O3M_14840 NC_018650.1 3029889 3030620 D COG0789 Predicted transcriptional regulators; DNA-binding transcriptional regulator 3029889..3030620 Escherichia coli O104:H4 str. 2009EL-2050 13689421 YP_006770602.1 CDS O3M_14845 NC_018650.1 3030841 3031245 D COG5562 Phage envelope protein; hypothetical protein 3030841..3031245 Escherichia coli O104:H4 str. 2009EL-2050 13689422 YP_006770603.1 CDS O3M_14850 NC_018650.1 3031941 3032264 D anti-adapter protein IraM 3031941..3032264 Escherichia coli O104:H4 str. 2009EL-2050 13689423 YP_006770604.1 CDS O3M_14855 NC_018650.1 3032367 3033617 R COG0538 Isocitrate dehydrogenases; isocitrate dehydrogenase complement(3032367..3033617) Escherichia coli O104:H4 str. 2009EL-2050 13689424 YP_006770605.1 CDS O3M_14860 NC_018650.1 3033789 3034442 D COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridine synthase E 3033789..3034442 Escherichia coli O104:H4 str. 2009EL-2050 13689425 YP_006770606.1 CDS O3M_14865 NC_018650.1 3034452 3034913 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase 3034452..3034913 Escherichia coli O104:H4 str. 2009EL-2050 13689426 YP_006770607.1 CDS mnmA NC_018650.1 3034967 3036073 D COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; tRNA-specific 2-thiouridylase MnmA 3034967..3036073 Escherichia coli O104:H4 str. 2009EL-2050 13689427 YP_006770608.1 CDS O3M_14875 NC_018650.1 3036109 3036750 D COG2915 Uncharacterized protein involved in purine metabolism; lysogenization regulator 3036109..3036750 Escherichia coli O104:H4 str. 2009EL-2050 13689428 YP_006770609.1 CDS O3M_14880 NC_018650.1 3036754 3038124 D COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 3036754..3038124 Escherichia coli O104:H4 str. 2009EL-2050 13689429 YP_006770610.1 CDS O3M_14885 NC_018650.1 3038292 3038963 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator PhoP 3038292..3038963 Escherichia coli O104:H4 str. 2009EL-2050 13689430 YP_006770611.1 CDS O3M_14890 NC_018650.1 3038963 3040423 D COG0642 Signal transduction histidine kinase; sensor protein PhoQ 3038963..3040423 Escherichia coli O104:H4 str. 2009EL-2050 13689431 YP_006770612.1 CDS O3M_14895 NC_018650.1 3040499 3041620 D COG2850 Uncharacterized conserved protein; hypothetical protein 3040499..3041620 Escherichia coli O104:H4 str. 2009EL-2050 13689432 YP_006770613.1 CDS O3M_14900 NC_018650.1 3041766 3042995 R COG2195 Di- and tripeptidases; peptidase T complement(3041766..3042995) Escherichia coli O104:H4 str. 2009EL-2050 13689433 YP_006770614.1 CDS potA NC_018650.1 3043245 3044381 D COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; putrescine/spermidine ABC transporter ATPase 3043245..3044381 Escherichia coli O104:H4 str. 2009EL-2050 13689434 YP_006770615.1 CDS potB NC_018650.1 3044365 3045222 D COG1176 ABC-type spermidine/putrescine transport system, permease component I; spermidine/putrescine ABC transporter permease 3044365..3045222 Escherichia coli O104:H4 str. 2009EL-2050 13689435 YP_006770616.1 CDS potC NC_018650.1 3045219 3046013 D COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease 3045219..3046013 Escherichia coli O104:H4 str. 2009EL-2050 13689436 YP_006770617.1 CDS potD NC_018650.1 3046010 3047056 D COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine ABC transporter substrate-binding protein 3046010..3047056 Escherichia coli O104:H4 str. 2009EL-2050 13689437 YP_006770618.1 CDS O3M_14925 NC_018650.1 3047114 3047575 D inner membrane protein 3047114..3047575 Escherichia coli O104:H4 str. 2009EL-2050 13689438 YP_006770619.1 CDS O3M_14930 NC_018650.1 3047650 3048360 D inner membrane protein 3047650..3048360 Escherichia coli O104:H4 str. 2009EL-2050 13689439 YP_006770620.1 CDS O3M_14935 NC_018650.1 3048499 3049320 R COG0846 NAD-dependent protein deacetylases, SIR2 family; NAD-dependent deacetylase complement(3048499..3049320) Escherichia coli O104:H4 str. 2009EL-2050 13689440 YP_006770621.1 CDS O3M_14940 NC_018650.1 3049336 3050247 R COG1940 Transcriptional regulator/sugar kinase; N-acetyl-D-glucosamine kinase complement(3049336..3050247) Escherichia coli O104:H4 str. 2009EL-2050 13689441 YP_006770622.1 CDS O3M_14945 NC_018650.1 3050276 3051520 R COG4591 ABC-type transport system, involved in lipoprotein release, permease component; outer membrane-specific lipoprotein transporter subunit LolE complement(3050276..3051520) Escherichia coli O104:H4 str. 2009EL-2050 13689442 YP_006770623.1 CDS lolD NC_018650.1 3051520 3052221 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; lipoprotein transporter ATP-binding subunit complement(3051520..3052221) Escherichia coli O104:H4 str. 2009EL-2050 13689443 YP_006770624.1 CDS O3M_14955 NC_018650.1 3052214 3053413 R COG4591 ABC-type transport system, involved in lipoprotein release, permease component; outer membrane-specific lipoprotein transporter subunit LolC complement(3052214..3053413) Escherichia coli O104:H4 str. 2009EL-2050 13689444 YP_006770625.1 CDS O3M_14960 NC_018650.1 3053675 3054748 D COG4763 Predicted membrane protein; inner membrane protein 3053675..3054748 Escherichia coli O104:H4 str. 2009EL-2050 13689445 YP_006770626.1 CDS O3M_14965 NC_018650.1 3054876 3058322 D COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 3054876..3058322 Escherichia coli O104:H4 str. 2009EL-2050 13689446 YP_006770627.1 CDS O3M_14970 NC_018650.1 3058466 3059428 D COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 3058466..3059428 Escherichia coli O104:H4 str. 2009EL-2050 13689447 YP_006770628.1 CDS O3M_14975 NC_018650.1 3059511 3059768 R hypothetical protein complement(3059511..3059768) Escherichia coli O104:H4 str. 2009EL-2050 13689448 YP_006770629.1 CDS O3M_14980 NC_018650.1 3060009 3060641 D COG1309 Transcriptional regulator; hypothetical protein 3060009..3060641 Escherichia coli O104:H4 str. 2009EL-2050 13689449 YP_006770630.1 CDS O3M_14985 NC_018650.1 3060703 3061242 R COG3134 Predicted outer membrane lipoprotein; hypothetical protein complement(3060703..3061242) Escherichia coli O104:H4 str. 2009EL-2050 13689450 YP_006770631.1 CDS O3M_14990 NC_018650.1 3061452 3062756 R COG1252 NADH dehydrogenase, FAD-containing subunit; respiratory NADH dehydrogenase 2/cupric reductase complement(3061452..3062756) Escherichia coli O104:H4 str. 2009EL-2050 13689451 YP_006770632.1 CDS O3M_14995 NC_018650.1 3063164 3063706 R COG3150 Predicted esterase; hypothetical protein complement(3063164..3063706) Escherichia coli O104:H4 str. 2009EL-2050 13689452 YP_006770633.1 CDS O3M_15000 NC_018650.1 3063729 3064754 R COG1472 Beta-glucosidase-related glycosidases; beta-hexosaminidase complement(3063729..3064754) Escherichia coli O104:H4 str. 2009EL-2050 13689453 YP_006770634.1 CDS thiK NC_018650.1 3064765 3065589 R COG0510 Predicted choline kinase involved in LPS biosynthesis; thiamine kinase complement(3064765..3065589) Escherichia coli O104:H4 str. 2009EL-2050 13689454 YP_006770635.1 CDS O3M_15010 NC_018650.1 3065570 3066211 R COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family); hypothetical protein complement(3065570..3066211) Escherichia coli O104:H4 str. 2009EL-2050 13689455 YP_006770636.1 CDS O3M_15015 NC_018650.1 3066225 3066602 R COG5633 Predicted periplasmic lipoprotein; lipoprotein complement(3066225..3066602) Escherichia coli O104:H4 str. 2009EL-2050 13689456 YP_006770637.1 CDS O3M_15020 NC_018650.1 3066605 3066964 R COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; purine nucleoside phosphoramidase complement(3066605..3066964) Escherichia coli O104:H4 str. 2009EL-2050 13689457 YP_006770638.1 CDS O3M_15025 NC_018650.1 3067298 3069487 D COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid; ferric-rhodotorulic acid outer membrane transporter 3067298..3069487 Escherichia coli O104:H4 str. 2009EL-2050 13689458 YP_006770639.1 CDS O3M_15030 NC_018650.1 3069547 3070980 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose-specific transporter subunit IIBC complement(3069547..3070980) Escherichia coli O104:H4 str. 2009EL-2050 13689459 YP_006770640.1 CDS O3M_15035 NC_018650.1 3071275 3072072 R COG0084 Mg-dependent DNase; DNAse complement(3071275..3072072) Escherichia coli O104:H4 str. 2009EL-2050 13689460 YP_006770641.1 CDS O3M_15040 NC_018650.1 3072083 3073087 R COG0470 ATPase involved in DNA replication; DNA polymerase III subunit delta' complement(3072083..3073087) Escherichia coli O104:H4 str. 2009EL-2050 13689461 YP_006770642.1 CDS tmk NC_018650.1 3073084 3073725 R COG0125 Thymidylate kinase; thymidylate kinase complement(3073084..3073725) Escherichia coli O104:H4 str. 2009EL-2050 13689462 YP_006770643.1 CDS O3M_15050 NC_018650.1 3073715 3074737 R COG1559 Predicted periplasmic solute-binding protein; aminodeoxychorismate lyase complement(3073715..3074737) Escherichia coli O104:H4 str. 2009EL-2050 13689463 YP_006770644.1 CDS O3M_15055 NC_018650.1 3074740 3075549 R COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; 4-amino-4-deoxychorismate lyase complement(3074740..3075549) Escherichia coli O104:H4 str. 2009EL-2050 13689464 YP_006770645.1 CDS O3M_15060 NC_018650.1 3075669 3076910 R COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-(acyl carrier protein) synthase II complement(3075669..3076910) Escherichia coli O104:H4 str. 2009EL-2050 13689465 YP_006770646.1 CDS O3M_15065 NC_018650.1 3076998 3077234 R COG0236 Acyl carrier protein; hypothetical protein complement(3076998..3077234) Escherichia coli O104:H4 str. 2009EL-2050 13689466 YP_006770647.1 CDS fabG NC_018650.1 3077445 3078179 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-ACP reductase complement(3077445..3078179) Escherichia coli O104:H4 str. 2009EL-2050 13689467 YP_006770648.1 CDS O3M_15075 NC_018650.1 3078192 3079121 R COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl-CoA-[acyl-carrier-protein] transacylase complement(3078192..3079121) Escherichia coli O104:H4 str. 2009EL-2050 13689468 YP_006770649.1 CDS O3M_15080 NC_018650.1 3079137 3080090 R COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-ACP synthase complement(3079137..3080090) Escherichia coli O104:H4 str. 2009EL-2050 13689469 YP_006770650.1 CDS O3M_15085 NC_018650.1 3080158 3081228 R COG0416 Fatty acid/phospholipid biosynthesis enzyme; phosphate acyltransferase complement(3080158..3081228) Escherichia coli O104:H4 str. 2009EL-2050 13689470 YP_006770651.1 CDS rpmF NC_018650.1 3081309 3081482 R COG0333 Ribosomal protein L32; 50S ribosomal protein L32 complement(3081309..3081482) Escherichia coli O104:H4 str. 2009EL-2050 13689471 YP_006770652.1 CDS O3M_15095 NC_018650.1 3081534 3082055 R COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; hypothetical protein complement(3081534..3082055) Escherichia coli O104:H4 str. 2009EL-2050 13689472 YP_006770653.1 CDS O3M_15100 NC_018650.1 3082254 3082838 D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; maf-like protein 3082254..3082838 Escherichia coli O104:H4 str. 2009EL-2050 13689473 YP_006770654.1 CDS O3M_15105 NC_018650.1 3082950 3083909 R COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA pseudouridylate synthase C complement(3082950..3083909) Escherichia coli O104:H4 str. 2009EL-2050 13689474 YP_006770655.1 CDS O3M_15110 NC_018650.1 3084027 3084401 R hypothetical protein complement(3084027..3084401) Escherichia coli O104:H4 str. 2009EL-2050 13689475 YP_006770656.1 CDS rne NC_018650.1 3084482 3087667 D COG1530 Ribonucleases G and E; ribonuclease E 3084482..3087667 Escherichia coli O104:H4 str. 2009EL-2050 13689476 YP_006770657.1 CDS flgL NC_018650.1 3087864 3088817 R COG1344 Flagellin and related hook-associated proteins; flagellar hook-associated protein FlgL complement(3087864..3088817) Escherichia coli O104:H4 str. 2009EL-2050 13689477 YP_006770658.1 CDS flgK NC_018650.1 3088829 3090472 R COG1256 Flagellar hook-associated protein; flagellar hook-associated protein FlgK complement(3088829..3090472) Escherichia coli O104:H4 str. 2009EL-2050 13689478 YP_006770659.1 CDS flgJ NC_018650.1 3090538 3091479 R COG3951 Rod binding protein; flagellar rod assembly protein/muramidase FlgJ complement(3090538..3091479) Escherichia coli O104:H4 str. 2009EL-2050 13689479 YP_006770660.1 CDS flgI NC_018650.1 3091479 3092576 R COG1706 Flagellar basal-body P-ring protein; flagellar basal body P-ring protein complement(3091479..3092576) Escherichia coli O104:H4 str. 2009EL-2050 13689480 YP_006770661.1 CDS flgH NC_018650.1 3092588 3093286 R COG2063 Flagellar basal body L-ring protein; flagellar basal body L-ring protein complement(3092588..3093286) Escherichia coli O104:H4 str. 2009EL-2050 13689481 YP_006770662.1 CDS flgG NC_018650.1 3093339 3094121 R COG4786 Flagellar basal body rod protein; flagellar basal body rod protein FlgG complement(3093339..3094121) Escherichia coli O104:H4 str. 2009EL-2050 13689482 YP_006770663.1 CDS flgF NC_018650.1 3094293 3095048 R COG4787 Flagellar basal body rod protein; flagellar basal body rod protein FlgF complement(3094293..3095048) Escherichia coli O104:H4 str. 2009EL-2050 13689483 YP_006770664.1 CDS flgE NC_018650.1 3095068 3096273 R COG1749 Flagellar hook protein FlgE; flagellar hook protein FlgE complement(3095068..3096273) Escherichia coli O104:H4 str. 2009EL-2050 13689484 YP_006770665.1 CDS flgD NC_018650.1 3096298 3096993 R COG1843 Flagellar hook capping protein; flagellar basal body rod modification protein complement(3096298..3096993) Escherichia coli O104:H4 str. 2009EL-2050 13689485 YP_006770666.1 CDS flgC NC_018650.1 3097005 3097409 R COG1558 Flagellar basal body rod protein; flagellar basal body rod protein FlgC complement(3097005..3097409) Escherichia coli O104:H4 str. 2009EL-2050 13689486 YP_006770667.1 CDS flgB NC_018650.1 3097413 3097829 R COG1815 Flagellar basal body protein; flagellar basal body rod protein FlgB complement(3097413..3097829) Escherichia coli O104:H4 str. 2009EL-2050 13689487 YP_006770668.1 CDS flgA NC_018650.1 3097984 3098643 D COG1261 Flagellar basal body P-ring biosynthesis protein; flagellar basal body P-ring biosynthesis protein FlgA 3097984..3098643 Escherichia coli O104:H4 str. 2009EL-2050 13689488 YP_006770669.1 CDS O3M_15180 NC_018650.1 3098719 3099012 D COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor); anti-sigma-28 factor FlgM 3098719..3099012 Escherichia coli O104:H4 str. 2009EL-2050 13689489 YP_006770670.1 CDS O3M_15185 NC_018650.1 3099017 3099433 D COG3418 Flagellar biosynthesis/type III secretory pathway chaperone; flagella synthesis chaperone protein FlgN 3099017..3099433 Escherichia coli O104:H4 str. 2009EL-2050 13689490 YP_006770671.1 CDS O3M_15190 NC_018650.1 3099473 3101008 R COG0728 Uncharacterized membrane protein, putative virulence factor; inner membrane protein MviN complement(3099473..3101008) Escherichia coli O104:H4 str. 2009EL-2050 13689491 YP_006770672.1 CDS O3M_15195 NC_018650.1 3101118 3102041 R COG0673 Predicted dehydrogenases and related proteins; oxidoreductase complement(3101118..3102041) Escherichia coli O104:H4 str. 2009EL-2050 13689492 YP_006770673.1 CDS O3M_15200 NC_018650.1 3102043 3102690 R COG3132 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3102043..3102690) Escherichia coli O104:H4 str. 2009EL-2050 13689493 YP_006770674.1 CDS O3M_15205 NC_018650.1 3102701 3103285 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-S5-alanine N-acetyltransferase complement(3102701..3103285) Escherichia coli O104:H4 str. 2009EL-2050 13689494 YP_006770675.1 CDS O3M_15210 NC_018650.1 3103521 3104729 D COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein MdtH 3103521..3104729 Escherichia coli O104:H4 str. 2009EL-2050 13689495 YP_006770676.1 CDS O3M_15215 NC_018650.1 3104793 3105440 D COG2999 Glutaredoxin 2; glutaredoxin 3104793..3105440 Escherichia coli O104:H4 str. 2009EL-2050 13689496 YP_006770677.1 CDS O3M_15220 NC_018650.1 3105574 3106134 D lipoprotein 3105574..3106134 Escherichia coli O104:H4 str. 2009EL-2050 13689497 YP_006770678.1 CDS O3M_15225 NC_018650.1 3106240 3107286 D COG0418 Dihydroorotase; dihydroorotase 3106240..3107286 Escherichia coli O104:H4 str. 2009EL-2050 13689498 YP_006770679.1 CDS O3M_15230 NC_018650.1 3107360 3107605 D DNA damage-inducible protein I 3107360..3107605 Escherichia coli O104:H4 str. 2009EL-2050 13689499 YP_006770680.1 CDS bssS NC_018650.1 3107895 3108149 D biofilm formation regulatory protein BssS 3107895..3108149 Escherichia coli O104:H4 str. 2009EL-2050 13689500 YP_006770681.1 CDS solA NC_018650.1 3108264 3109382 D COG0665 Glycine/D-amino acid oxidases (deaminating); N-methyltryptophan oxidase 3108264..3109382 Escherichia coli O104:H4 str. 2009EL-2050 13689501 YP_006770682.1 CDS O3M_15245 NC_018650.1 3109430 3109543 D hypothetical protein 3109430..3109543 Escherichia coli O104:H4 str. 2009EL-2050 13689502 YP_006770683.1 CDS O3M_15250 NC_018650.1 3109804 3110370 D COG3038 Cytochrome B561; cytochrome 3109804..3110370 Escherichia coli O104:H4 str. 2009EL-2050 13689503 YP_006770684.1 CDS O3M_15255 NC_018650.1 3110374 3110949 D COG2353 Uncharacterized conserved protein; hypothetical protein 3110374..3110949 Escherichia coli O104:H4 str. 2009EL-2050 13689504 YP_006770685.1 CDS O3M_15260 NC_018650.1 3110991 3112043 R COG1054 Predicted sulfurtransferase; rhodanese-related sulfurtransferase complement(3110991..3112043) Escherichia coli O104:H4 str. 2009EL-2050 13689505 YP_006770686.1 CDS O3M_15265 NC_018650.1 3112268 3113188 D COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis lauroyl acyltransferase 3112268..3113188 Escherichia coli O104:H4 str. 2009EL-2050 13689506 YP_006770687.1 CDS O3M_15270 NC_018650.1 3113360 3114586 D COG0477 Permeases of the major facilitator superfamily; drug efflux system protein MdtG 3113360..3114586 Escherichia coli O104:H4 str. 2009EL-2050 13689507 YP_006770688.1 CDS O3M_15275 NC_018650.1 3114669 3115043 D secY/secA suppressor protein 3114669..3115043 Escherichia coli O104:H4 str. 2009EL-2050 13689508 YP_006770689.1 CDS O3M_15280 NC_018650.1 3115044 3115271 R COG5645 Predicted periplasmic lipoprotein; lipoprotein complement(3115044..3115271) Escherichia coli O104:H4 str. 2009EL-2050 13689509 YP_006770690.1 CDS O3M_15285 NC_018650.1 3115444 3117987 R COG2943 Membrane glycosyltransferase; glucosyltransferase MdoH complement(3115444..3117987) Escherichia coli O104:H4 str. 2009EL-2050 13689510 YP_006770691.1 CDS mdoG NC_018650.1 3117980 3119515 R COG3131 Periplasmic glucans biosynthesis protein; glucan biosynthesis protein G complement(3117980..3119515) Escherichia coli O104:H4 str. 2009EL-2050 13689511 YP_006770692.1 CDS opgC NC_018650.1 3119909 3121066 D glucans biosynthesis protein 3119909..3121066 Escherichia coli O104:H4 str. 2009EL-2050 13689512 YP_006770693.1 CDS O3M_15300 NC_018650.1 3121074 3122495 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phospholipase D/transphosphatidylase complement(3121074..3122495) Escherichia coli O104:H4 str. 2009EL-2050 13689513 YP_006770694.1 CDS O3M_15305 NC_018650.1 3122497 3123030 R COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; RNase III inhibitor complement(3122497..3123030) Escherichia coli O104:H4 str. 2009EL-2050 13689514 YP_006770695.1 CDS O3M_15310 NC_018650.1 3123125 3123325 R hypothetical protein complement(3123125..3123325) Escherichia coli O104:H4 str. 2009EL-2050 13689515 YP_006770696.1 CDS csgC NC_018650.1 3123556 3123888 R curli assembly protein CsgC complement(3123556..3123888) Escherichia coli O104:H4 str. 2009EL-2050 13689516 YP_006770697.1 CDS csgA NC_018650.1 3123947 3124402 R major curlin subunit complement(3123947..3124402) Escherichia coli O104:H4 str. 2009EL-2050 13689517 YP_006770698.1 CDS csgB NC_018650.1 3124443 3124898 R curlin minor subunit CsgB complement(3124443..3124898) Escherichia coli O104:H4 str. 2009EL-2050 13689518 YP_006770699.1 CDS O3M_15330 NC_018650.1 3125652 3126302 D COG2771 DNA-binding HTH domain-containing proteins; DNA-binding transcriptional regulator CsgD 3125652..3126302 Escherichia coli O104:H4 str. 2009EL-2050 13689519 YP_006770700.1 CDS O3M_15335 NC_018650.1 3126307 3126696 D COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; curli assembly protein CsgE 3126307..3126696 Escherichia coli O104:H4 str. 2009EL-2050 13689520 YP_006770701.1 CDS O3M_15340 NC_018650.1 3126721 3127137 D curli assembly protein CsgF 3126721..3127137 Escherichia coli O104:H4 str. 2009EL-2050 13689521 YP_006770702.1 CDS O3M_15345 NC_018650.1 3127164 3127997 D COG1462 Uncharacterized protein involved in formation of curli polymers; curli production assembly/transport protein CsgG 3127164..3127997 Escherichia coli O104:H4 str. 2009EL-2050 13689522 YP_006770703.1 CDS O3M_15350 NC_018650.1 3128061 3128552 R inner membrane protein complement(3128061..3128552) Escherichia coli O104:H4 str. 2009EL-2050 13689523 YP_006770704.1 CDS O3M_15355 NC_018650.1 3128654 3129208 R COG3381 Uncharacterized component of anaerobic dehydrogenases; hypothetical protein complement(3128654..3129208) Escherichia coli O104:H4 str. 2009EL-2050 13689524 YP_006770705.1 CDS O3M_15360 NC_018650.1 3129232 3129969 R COG1387 Histidinol phosphatase and related hydrolases of the PHP family; hydrolase complement(3129232..3129969) Escherichia coli O104:H4 str. 2009EL-2050 13689525 YP_006770706.1 CDS ghrA NC_018650.1 3130024 3130962 R COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; bifunctional glyoxylate/hydroxypyruvate reductase A complement(3130024..3130962) Escherichia coli O104:H4 str. 2009EL-2050 13689526 YP_006770707.1 CDS O3M_15370 NC_018650.1 3131433 3132275 R hypothetical protein complement(3131433..3132275) Escherichia coli O104:H4 str. 2009EL-2050 13689528 YP_006770708.1 CDS O3M_15375 NC_018650.1 3132360 3132557 R hypothetical protein complement(3132360..3132557) Escherichia coli O104:H4 str. 2009EL-2050 13689529 YP_006770709.1 CDS O3M_15380 NC_018650.1 3132569 3133057 R hypothetical protein complement(3132569..3133057) Escherichia coli O104:H4 str. 2009EL-2050 13689530 YP_006770710.1 CDS O3M_15385 NC_018650.1 3133057 3133431 R hypothetical protein complement(3133057..3133431) Escherichia coli O104:H4 str. 2009EL-2050 13689531 YP_006770711.1 CDS O3M_15390 NC_018650.1 3133522 3133875 R CP4-44 prophage YeeV-YeeU toxin-antitoxin system toxin complement(3133522..3133875) Escherichia coli O104:H4 str. 2009EL-2050 13689532 YP_006770712.1 CDS O3M_15395 NC_018650.1 3133951 3134172 R hypothetical protein complement(3133951..3134172) Escherichia coli O104:H4 str. 2009EL-2050 13689533 YP_006770713.1 CDS O3M_15400 NC_018650.1 3134235 3134711 R COG2003 DNA repair proteins; radC-like protein YeeS complement(3134235..3134711) Escherichia coli O104:H4 str. 2009EL-2050 13689534 YP_006770714.1 CDS O3M_15405 NC_018650.1 3134727 3135200 R hypothetical protein complement(3134727..3135200) Escherichia coli O104:H4 str. 2009EL-2050 13689535 YP_006770715.1 CDS O3M_15410 NC_018650.1 3135294 3135539 R hypothetical protein complement(3135294..3135539) Escherichia coli O104:H4 str. 2009EL-2050 13689536 YP_006770716.1 CDS O3M_15415 NC_018650.1 3135539 3136360 R hypothetical protein complement(3135539..3136360) Escherichia coli O104:H4 str. 2009EL-2050 13689537 YP_006770717.1 CDS O3M_15420 NC_018650.1 3136608 3138221 R COG3436 Transposase and inactivated derivatives; transposase complement(3136608..3138221) Escherichia coli O104:H4 str. 2009EL-2050 13689538 YP_006770718.1 CDS O3M_15425 NC_018650.1 3138252 3138602 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(3138252..3138602) Escherichia coli O104:H4 str. 2009EL-2050 13689539 YP_006770719.1 CDS O3M_15430 NC_018650.1 3138599 3139033 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(3138599..3139033) Escherichia coli O104:H4 str. 2009EL-2050 13689540 YP_006770720.1 CDS O3M_15435 NC_018650.1 3139130 3139540 R hypothetical protein complement(3139130..3139540) Escherichia coli O104:H4 str. 2009EL-2050 13689541 YP_006770721.1 CDS O3M_15440 NC_018650.1 3139556 3140239 R hypothetical protein complement(3139556..3140239) Escherichia coli O104:H4 str. 2009EL-2050 13689542 YP_006770722.1 CDS O3M_15445 NC_018650.1 3140373 3141443 R COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein complement(3140373..3141443) Escherichia coli O104:H4 str. 2009EL-2050 13689543 YP_006770723.1 CDS O3M_15450 NC_018650.1 3141440 3142345 R hypothetical protein complement(3141440..3142345) Escherichia coli O104:H4 str. 2009EL-2050 13689544 YP_006770724.1 CDS O3M_15455 NC_018650.1 3142342 3144738 R COG0699 Predicted GTPases (dynamin-related); hypothetical protein complement(3142342..3144738) Escherichia coli O104:H4 str. 2009EL-2050 13689545 YP_006770725.1 CDS O3M_15475 NC_018650.1 3147210 3148082 R COG3596 Predicted GTPase; GTP-binding protein complement(3147210..3148082) Escherichia coli O104:H4 str. 2009EL-2050 13689546 YP_006770726.1 CDS O3M_15480 NC_018650.1 3148894 3149319 R COG2963 Transposase and inactivated derivatives; IS66 transposase complement(3148894..3149319) Escherichia coli O104:H4 str. 2009EL-2050 13689547 YP_006770727.1 CDS O3M_15485 NC_018650.1 3149477 3150718 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein TerF complement(3149477..3150718) Escherichia coli O104:H4 str. 2009EL-2050 13689548 YP_006770728.1 CDS O3M_15490 NC_018650.1 3151150 3151725 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein TerE complement(3151150..3151725) Escherichia coli O104:H4 str. 2009EL-2050 13689549 YP_006770729.1 CDS O3M_15495 NC_018650.1 3151794 3152372 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein complement(3151794..3152372) Escherichia coli O104:H4 str. 2009EL-2050 13689550 YP_006770730.1 CDS O3M_15500 NC_018650.1 3152421 3153461 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; Tellurium resistance protein TerC complement(3152421..3153461) Escherichia coli O104:H4 str. 2009EL-2050 13689551 YP_006770731.1 CDS O3M_15505 NC_018650.1 3153484 3153939 R COG3793 Tellurite resistance protein; tellurium resistance protein TerB complement(3153484..3153939) Escherichia coli O104:H4 str. 2009EL-2050 13689552 YP_006770732.1 CDS O3M_15510 NC_018650.1 3153962 3155119 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein TerA complement(3153962..3155119) Escherichia coli O104:H4 str. 2009EL-2050 13689553 YP_006770733.1 CDS O3M_15515 NC_018650.1 3155119 3155700 R COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein complement(3155119..3155700) Escherichia coli O104:H4 str. 2009EL-2050 13689554 YP_006770734.1 CDS O3M_15520 NC_018650.1 3156023 3157081 D COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein 3156023..3157081 Escherichia coli O104:H4 str. 2009EL-2050 13689555 YP_006770735.1 CDS O3M_15525 NC_018650.1 3157091 3158233 D hypothetical protein 3157091..3158233 Escherichia coli O104:H4 str. 2009EL-2050 13689556 YP_006770736.1 CDS O3M_15530 NC_018650.1 3158226 3158999 D COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 3158226..3158999 Escherichia coli O104:H4 str. 2009EL-2050 13689557 YP_006770737.1 CDS O3M_15535 NC_018650.1 3159001 3160080 D ATP-binding protein 3159001..3160080 Escherichia coli O104:H4 str. 2009EL-2050 13689558 YP_006770738.1 CDS O3M_15540 NC_018650.1 3160080 3161036 D COG2301 Citrate lyase beta subunit; hypothetical protein 3160080..3161036 Escherichia coli O104:H4 str. 2009EL-2050 13689559 YP_006770739.1 CDS O3M_15545 NC_018650.1 3161047 3162255 D hypothetical protein 3161047..3162255 Escherichia coli O104:H4 str. 2009EL-2050 13689560 YP_006770740.1 CDS O3M_15550 NC_018650.1 3162273 3162740 D tellurium resistance protein TerW 3162273..3162740 Escherichia coli O104:H4 str. 2009EL-2050 13689561 YP_006770741.1 CDS O3M_15555 NC_018650.1 3163204 3163842 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY1 3163204..3163842 Escherichia coli O104:H4 str. 2009EL-2050 13689562 YP_006770742.1 CDS O3M_15560 NC_018650.1 3163865 3164503 D COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein terX 3163865..3164503 Escherichia coli O104:H4 str. 2009EL-2050 13689563 YP_006770743.1 CDS O3M_15565 NC_018650.1 3164503 3165141 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY2 3164503..3165141 Escherichia coli O104:H4 str. 2009EL-2050 13689564 YP_006770744.1 CDS O3M_15570 NC_018650.1 3165226 3166266 D COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY3 3165226..3166266 Escherichia coli O104:H4 str. 2009EL-2050 13689565 YP_006770745.1 CDS O3M_15575 NC_018650.1 3166266 3167903 D hypothetical protein 3166266..3167903 Escherichia coli O104:H4 str. 2009EL-2050 13689566 YP_006770746.1 CDS O3M_15580 NC_018650.1 3167929 3169428 D COG0515 Serine/threonine protein kinase; protein kinase 3167929..3169428 Escherichia coli O104:H4 str. 2009EL-2050 13689567 YP_006770747.1 CDS O3M_15585 NC_018650.1 3169516 3170184 D COG4584 Transposase and inactivated derivatives; transposase 3169516..3170184 Escherichia coli O104:H4 str. 2009EL-2050 13689568 YP_006770748.1 CDS O3M_15590 NC_018650.1 3170259 3170444 D COG1484 DNA replication protein; IS100 transposase 3170259..3170444 Escherichia coli O104:H4 str. 2009EL-2050 13689569 YP_006770749.1 CDS O3M_15595 NC_018650.1 3171013 3171189 D hypothetical protein 3171013..3171189 Escherichia coli O104:H4 str. 2009EL-2050 13689571 YP_006770750.1 CDS O3M_15600 NC_018650.1 3171809 3172054 D COG1943 Transposase and inactivated derivatives; transposase IS605 family, IS200 group 3171809..3172054 Escherichia coli O104:H4 str. 2009EL-2050 13689572 YP_006770751.1 CDS O3M_15605 NC_018650.1 3172172 3173110 R COG0583 Transcriptional regulator; cell density-dependent motility repressor complement(3172172..3173110) Escherichia coli O104:H4 str. 2009EL-2050 13689573 YP_006770752.1 CDS O3M_15610 NC_018650.1 3173461 3174180 D COG1794 Aspartate racemase; aspartate racemase 3173461..3174180 Escherichia coli O104:H4 str. 2009EL-2050 13689574 YP_006770753.1 CDS O3M_15615 NC_018650.1 3174246 3175544 D COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 3174246..3175544 Escherichia coli O104:H4 str. 2009EL-2050 13689575 YP_006770754.1 CDS O3M_15620 NC_018650.1 3175788 3176501 R COG2801 Transposase and inactivated derivatives; IS600 orfB complement(3175788..3176501) Escherichia coli O104:H4 str. 2009EL-2050 13689576 YP_006770755.1 CDS O3M_15625 NC_018650.1 3176586 3176795 R COG1662 Transposase and inactivated derivatives, IS1 family; insertion element protein complement(3176586..3176795) Escherichia coli O104:H4 str. 2009EL-2050 13689577 YP_006770756.1 CDS O3M_15630 NC_018650.1 3176796 3177089 R IS1; transposase ORF B, IS1 complement(3176796..3177089) Escherichia coli O104:H4 str. 2009EL-2050 13689578 YP_006770757.1 CDS O3M_15635 NC_018650.1 3177008 3177283 R COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA complement(3177008..3177283) Escherichia coli O104:H4 str. 2009EL-2050 13689579 YP_006770758.1 CDS O3M_15640 NC_018650.1 3177312 3177431 R hypothetical protein complement(3177312..3177431) Escherichia coli O104:H4 str. 2009EL-2050 13689580 YP_006770759.1 CDS O3M_15645 NC_018650.1 3177551 3178648 R COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase; hypothetical protein complement(3177551..3178648) Escherichia coli O104:H4 str. 2009EL-2050 13689581 YP_006770760.1 CDS O3M_15650 NC_018650.1 3179157 3181376 R COG1112 Superfamily I DNA and RNA helicases and helicase subunits; UvrD/REP helicase-like protein complement(3179157..3181376) Escherichia coli O104:H4 str. 2009EL-2050 13689582 YP_006770761.1 CDS O3M_15655 NC_018650.1 3182080 3182655 R hypothetical protein complement(3182080..3182655) Escherichia coli O104:H4 str. 2009EL-2050 13689583 YP_006770762.1 CDS O3M_15660 NC_018650.1 3183401 3183619 R hypothetical protein complement(3183401..3183619) Escherichia coli O104:H4 str. 2009EL-2050 13689584 YP_006770763.1 CDS O3M_15665 NC_018650.1 3183630 3183863 R hypothetical protein complement(3183630..3183863) Escherichia coli O104:H4 str. 2009EL-2050 13689585 YP_006770764.1 CDS O3M_15670 NC_018650.1 3183959 3184582 R hypothetical protein complement(3183959..3184582) Escherichia coli O104:H4 str. 2009EL-2050 13689586 YP_006770765.1 CDS O3M_15675 NC_018650.1 3186525 3186881 D COG1266 Predicted metal-dependent membrane protease; hypothetical protein 3186525..3186881 Escherichia coli O104:H4 str. 2009EL-2050 13689587 YP_006770766.1 CDS O3M_15680 NC_018650.1 3187877 3189979 R COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; colicin V secretion/processing ATP binding protein complement(3187877..3189979) Escherichia coli O104:H4 str. 2009EL-2050 13689588 YP_006770767.1 CDS O3M_15685 NC_018650.1 3189972 3191159 R COG0845 Membrane-fusion protein; Colicin V secretion protein CvaA complement(3189972..3191159) Escherichia coli O104:H4 str. 2009EL-2050 13689589 YP_006770768.1 CDS O3M_15690 NC_018650.1 3191399 3191851 R COG2994 ACP:hemolysin acyltransferase (hemolysin-activating protein); hypothetical protein complement(3191399..3191851) Escherichia coli O104:H4 str. 2009EL-2050 13689590 YP_006770769.1 CDS O3M_15695 NC_018650.1 3191877 3193427 R hypothetical protein complement(3191877..3193427) Escherichia coli O104:H4 str. 2009EL-2050 13689591 YP_006770770.1 CDS O3M_15700 NC_018650.1 3194976 3195410 D COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); hypothetical protein 3194976..3195410 Escherichia coli O104:H4 str. 2009EL-2050 13689592 YP_006770771.1 CDS O3M_15705 NC_018650.1 3195563 3196543 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 3195563..3196543 Escherichia coli O104:H4 str. 2009EL-2050 13689593 YP_006770772.1 CDS O3M_15710 NC_018650.1 3197158 3198423 D COG2382 Enterochelin esterase and related enzymes; ferric enterochelin esterase 3197158..3198423 Escherichia coli O104:H4 str. 2009EL-2050 13689594 YP_006770773.1 CDS O3M_15715 NC_018650.1 3198565 3199689 R COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; glucosyl-transferase complement(3198565..3199689) Escherichia coli O104:H4 str. 2009EL-2050 13689595 YP_006770774.1 CDS O3M_15720 NC_018650.1 3200419 3200616 R COG3311 Predicted transcriptional regulator; DNA binding protein complement(3200419..3200616) Escherichia coli O104:H4 str. 2009EL-2050 13689596 YP_006770775.1 CDS O3M_15725 NC_018650.1 3200682 3200876 R hypothetical protein complement(3200682..3200876) Escherichia coli O104:H4 str. 2009EL-2050 13689597 YP_006770776.1 CDS O3M_15730 NC_018650.1 3201098 3201181 D hypothetical protein 3201098..3201181 Escherichia coli O104:H4 str. 2009EL-2050 13689598 YP_006770777.1 CDS O3M_15735 NC_018650.1 3201778 3201972 D hypothetical protein 3201778..3201972 Escherichia coli O104:H4 str. 2009EL-2050 13689599 YP_006770778.1 CDS O3M_15740 NC_018650.1 3202333 3202461 D COG2801 Transposase and inactivated derivatives; hypothetical protein 3202333..3202461 Escherichia coli O104:H4 str. 2009EL-2050 13689600 YP_006770779.1 CDS O3M_15745 NC_018650.1 3202943 3203107 R hypothetical protein complement(3202943..3203107) Escherichia coli O104:H4 str. 2009EL-2050 13689601 YP_006770780.1 CDS O3M_15750 NC_018650.1 3203741 3203959 R hypothetical protein complement(3203741..3203959) Escherichia coli O104:H4 str. 2009EL-2050 13689602 YP_006770781.1 CDS O3M_15755 NC_018650.1 3205291 3205473 R hypothetical protein complement(3205291..3205473) Escherichia coli O104:H4 str. 2009EL-2050 13689603 YP_006770782.1 CDS O3M_15760 NC_018650.1 3205412 3207502 D COG4771 Outer membrane receptor for ferrienterochelin and colicins; bifunctional enterobactin receptor/adhesin protein 3205412..3207502 Escherichia coli O104:H4 str. 2009EL-2050 13689604 YP_006770783.1 CDS O3M_15765 NC_018650.1 3207736 3207960 D hypothetical protein 3207736..3207960 Escherichia coli O104:H4 str. 2009EL-2050 13689605 YP_006770784.1 CDS O3M_15770 NC_018650.1 3208198 3208602 D COG2963 Transposase and inactivated derivatives; ISSfl3 protein 3208198..3208602 Escherichia coli O104:H4 str. 2009EL-2050 13689606 YP_006770785.1 CDS O3M_15775 NC_018650.1 3208599 3208946 D COG3436 Transposase and inactivated derivatives; IS66 family element 3208599..3208946 Escherichia coli O104:H4 str. 2009EL-2050 13689607 YP_006770786.1 CDS O3M_15790 NC_018650.1 3210190 3210378 D hypothetical protein 3210190..3210378 Escherichia coli O104:H4 str. 2009EL-2050 13689608 YP_006770787.1 CDS O3M_15795 NC_018650.1 3210396 3212756 R COG4951 Uncharacterized protein conserved in bacteria; helicase complement(3210396..3212756) Escherichia coli O104:H4 str. 2009EL-2050 13689609 YP_006770788.1 CDS O3M_15800 NC_018650.1 3212911 3213474 R hypothetical protein complement(3212911..3213474) Escherichia coli O104:H4 str. 2009EL-2050 13689610 YP_006770789.1 CDS O3M_15805 NC_018650.1 3214810 3216645 R hypothetical protein complement(3214810..3216645) Escherichia coli O104:H4 str. 2009EL-2050 13689611 YP_006770790.1 CDS O3M_15810 NC_018650.1 3216746 3217033 D COG3311 Predicted transcriptional regulator; regulatory protein 3216746..3217033 Escherichia coli O104:H4 str. 2009EL-2050 13689612 YP_006770791.1 CDS O3M_15815 NC_018650.1 3217008 3218534 D hypothetical protein 3217008..3218534 Escherichia coli O104:H4 str. 2009EL-2050 13689613 YP_006770792.1 CDS O3M_15820 NC_018650.1 3218704 3219921 R COG0582 Integrase; integrase complement(3218704..3219921) Escherichia coli O104:H4 str. 2009EL-2050 13689614 YP_006770793.1 CDS O3M_15825 NC_018650.1 3220469 3221455 R inner membrane protein complement(3220469..3221455) Escherichia coli O104:H4 str. 2009EL-2050 13689615 YP_006770794.1 CDS O3M_15830 NC_018650.1 3221452 3221997 R COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl CoA-ACP transacylase complement(3221452..3221997) Escherichia coli O104:H4 str. 2009EL-2050 13689616 YP_006770795.1 CDS O3M_15835 NC_018650.1 3221984 3223342 R COG2199 FOG: GGDEF domain; diguanylate cyclase complement(3221984..3223342) Escherichia coli O104:H4 str. 2009EL-2050 13689617 YP_006770796.1 CDS pgaA NC_018650.1 3223929 3226352 D COG0457 FOG: TPR repeat; outer membrane protein PgaA 3223929..3226352 Escherichia coli O104:H4 str. 2009EL-2050 13689618 YP_006770797.1 CDS pgaB NC_018650.1 3226361 3228379 D COG0726 Predicted xylanase/chitin deacetylase; outer membrane N-deacetylase 3226361..3228379 Escherichia coli O104:H4 str. 2009EL-2050 13689619 YP_006770798.1 CDS O3M_15850 NC_018650.1 3228372 3229697 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; N-glycosyltransferase 3228372..3229697 Escherichia coli O104:H4 str. 2009EL-2050 13689620 YP_006770799.1 CDS pgaD NC_018650.1 3229699 3230112 D PGA biosynthesis protein 3229699..3230112 Escherichia coli O104:H4 str. 2009EL-2050 13689621 YP_006770800.1 CDS O3M_15860 NC_018650.1 3230162 3230950 R COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; hypothetical protein complement(3230162..3230950) Escherichia coli O104:H4 str. 2009EL-2050 13689622 YP_006770801.1 CDS O3M_15865 NC_018650.1 3231569 3232840 R COG2837 Predicted iron-dependent peroxidase; hypothetical protein complement(3231569..3232840) Escherichia coli O104:H4 str. 2009EL-2050 13689623 YP_006770802.1 CDS O3M_15870 NC_018650.1 3232846 3233973 R COG2822 Predicted periplasmic lipoprotein involved in iron transport; inactive ferrous ion transporter periplasmic protein EfeO complement(3232846..3233973) Escherichia coli O104:H4 str. 2009EL-2050 13689624 YP_006770803.1 CDS O3M_15875 NC_018650.1 3234031 3234861 R COG0672 High-affinity Fe2+/Pb2+ permease; high-affinity Fe2+/Pb2+ permease complement(3234031..3234861) Escherichia coli O104:H4 str. 2009EL-2050 13689625 YP_006770804.1 CDS O3M_15880 NC_018650.1 3235403 3236911 R COG0591 Na+/proline symporter; proline:sodium symporter PutP complement(3235403..3236911) Escherichia coli O104:H4 str. 2009EL-2050 13689626 YP_006770805.1 CDS O3M_15885 NC_018650.1 3237070 3237279 R hypothetical protein complement(3237070..3237279) Escherichia coli O104:H4 str. 2009EL-2050 13689627 YP_006770806.1 CDS putA NC_018650.1 3237334 3241296 D COG0506 Proline dehydrogenase; multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 3237334..3241296 Escherichia coli O104:H4 str. 2009EL-2050 13689628 YP_006770807.1 CDS O3M_15895 NC_018650.1 3241336 3241974 R COG1309 Transcriptional regulator; HTH-type transcriptional regulator RutR complement(3241336..3241974) Escherichia coli O104:H4 str. 2009EL-2050 13689629 YP_006770808.1 CDS O3M_15900 NC_018650.1 3242262 3243353 D COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; monooxygenase of the alternative pyrimidine degradation pathway 3242262..3243353 Escherichia coli O104:H4 str. 2009EL-2050 13689630 YP_006770809.1 CDS O3M_15905 NC_018650.1 3243353 3244045 D COG1335 Amidases related to nicotinamidase; hypothetical protein 3243353..3244045 Escherichia coli O104:H4 str. 2009EL-2050 13689631 YP_006770810.1 CDS O3M_15910 NC_018650.1 3244057 3244443 D COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 3244057..3244443 Escherichia coli O104:H4 str. 2009EL-2050 13689632 YP_006770811.1 CDS O3M_15915 NC_018650.1 3244451 3245251 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); enzyme of the alternative pyrimidine degradation pathway 3244451..3245251 Escherichia coli O104:H4 str. 2009EL-2050 13689633 YP_006770812.1 CDS O3M_15920 NC_018650.1 3245261 3245851 D COG0778 Nitroreductase; malonic semialdehyde reductase 3245261..3245851 Escherichia coli O104:H4 str. 2009EL-2050 13689634 YP_006770813.1 CDS O3M_15925 NC_018650.1 3245862 3246356 D COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; flavin:NADH oxidoreductase subunit of alternative pyrimidine degradation pathway 3245862..3246356 Escherichia coli O104:H4 str. 2009EL-2050 13689635 YP_006770814.1 CDS O3M_15930 NC_018650.1 3246377 3247705 D COG2233 Xanthine/uracil permeases; transporter 3246377..3247705 Escherichia coli O104:H4 str. 2009EL-2050 13689636 YP_006770815.1 CDS O3M_15935 NC_018650.1 3247788 3247961 R COG3729 General stress protein; hypothetical protein complement(3247788..3247961) Escherichia coli O104:H4 str. 2009EL-2050 13689637 YP_006770817.1 CDS O3M_15945 NC_018650.1 3248893 3257274 R hypothetical protein complement(3248893..3257274) Escherichia coli O104:H4 str. 2009EL-2050 13689639 YP_006770818.1 CDS O3M_15950 NC_018650.1 3257344 3258609 R hypothetical protein complement(3257344..3258609) Escherichia coli O104:H4 str. 2009EL-2050 13689640 YP_006770819.1 CDS O3M_15955 NC_018650.1 3258620 3258871 R hypothetical protein complement(3258620..3258871) Escherichia coli O104:H4 str. 2009EL-2050 13689641 YP_006770820.1 CDS O3M_15960 NC_018650.1 3258881 3259327 R hypothetical protein complement(3258881..3259327) Escherichia coli O104:H4 str. 2009EL-2050 13689642 YP_006770821.1 CDS O3M_15965 NC_018650.1 3259330 3259986 R hypothetical protein complement(3259330..3259986) Escherichia coli O104:H4 str. 2009EL-2050 13689643 YP_006770822.1 CDS O3M_15970 NC_018650.1 3260081 3260482 R hypothetical protein complement(3260081..3260482) Escherichia coli O104:H4 str. 2009EL-2050 13689644 YP_006770823.1 CDS O3M_15975 NC_018650.1 3260539 3260679 R hypothetical protein complement(3260539..3260679) Escherichia coli O104:H4 str. 2009EL-2050 13689645 YP_006770824.1 CDS O3M_15980 NC_018650.1 3260910 3261644 R outer membrane protein Lom complement(3260910..3261644) Escherichia coli O104:H4 str. 2009EL-2050 13689646 YP_006770825.1 CDS O3M_15985 NC_018650.1 3261735 3262352 R hypothetical protein complement(3261735..3262352) Escherichia coli O104:H4 str. 2009EL-2050 13689647 YP_006770826.1 CDS O3M_15990 NC_018650.1 3262358 3262636 R outer membrane protein complement(3262358..3262636) Escherichia coli O104:H4 str. 2009EL-2050 13689648 YP_006770827.1 CDS O3M_15995 NC_018650.1 3262651 3263919 R COG4733 Phage-related protein, tail component; tail tip fiber protein complement(3262651..3263919) Escherichia coli O104:H4 str. 2009EL-2050 13689649 YP_006770828.1 CDS O3M_16000 NC_018650.1 3263916 3265607 R hypothetical protein complement(3263916..3265607) Escherichia coli O104:H4 str. 2009EL-2050 13689650 YP_006770829.1 CDS O3M_16005 NC_018650.1 3265775 3266287 R hypothetical protein complement(3265775..3266287) Escherichia coli O104:H4 str. 2009EL-2050 13689651 YP_006770830.1 CDS O3M_16010 NC_018650.1 3266374 3268965 R tail fiber protein complement(3266374..3268965) Escherichia coli O104:H4 str. 2009EL-2050 13689652 YP_006770831.1 CDS O3M_16015 NC_018650.1 3268962 3269612 R hypothetical protein complement(3268962..3269612) Escherichia coli O104:H4 str. 2009EL-2050 13689653 YP_006770832.1 CDS O3M_16020 NC_018650.1 3269612 3270175 R hypothetical protein complement(3269612..3270175) Escherichia coli O104:H4 str. 2009EL-2050 13689654 YP_006770833.1 CDS O3M_16025 NC_018650.1 3270159 3270620 R hypothetical protein complement(3270159..3270620) Escherichia coli O104:H4 str. 2009EL-2050 13689655 YP_006770834.1 CDS O3M_16030 NC_018650.1 3270671 3271060 R hypothetical protein complement(3270671..3271060) Escherichia coli O104:H4 str. 2009EL-2050 13689656 YP_006770835.1 CDS O3M_16035 NC_018650.1 3271115 3272329 R hypothetical protein complement(3271115..3272329) Escherichia coli O104:H4 str. 2009EL-2050 13689657 YP_006770836.1 CDS O3M_16040 NC_018650.1 3272353 3273360 R COG0061 Predicted sugar kinase; hypothetical protein complement(3272353..3273360) Escherichia coli O104:H4 str. 2009EL-2050 13689658 YP_006770837.1 CDS O3M_16045 NC_018650.1 3273518 3275662 R portal protein complement(3273518..3275662) Escherichia coli O104:H4 str. 2009EL-2050 13689659 YP_006770838.1 CDS O3M_16050 NC_018650.1 3275662 3277368 R terminase large subunit complement(3275662..3277368) Escherichia coli O104:H4 str. 2009EL-2050 13689660 YP_006770839.1 CDS O3M_16055 NC_018650.1 3277349 3278155 R terminase small subunit of bacteriophage BP-933W complement(3277349..3278155) Escherichia coli O104:H4 str. 2009EL-2050 13689661 YP_006770840.1 CDS O3M_16060 NC_018650.1 3278564 3278857 D Bor protein 3278564..3278857 Escherichia coli O104:H4 str. 2009EL-2050 13689662 YP_006770841.1 CDS O3M_16065 NC_018650.1 3278889 3279353 R endopeptidase complement(3278889..3279353) Escherichia coli O104:H4 str. 2009EL-2050 13689663 YP_006770842.1 CDS O3M_16070 NC_018650.1 3279361 3279495 R hypothetical protein complement(3279361..3279495) Escherichia coli O104:H4 str. 2009EL-2050 13689664 YP_006770843.1 CDS O3M_16075 NC_018650.1 3279510 3280079 R antirepressor complement(3279510..3280079) Escherichia coli O104:H4 str. 2009EL-2050 13689665 YP_006770844.1 CDS O3M_16080 NC_018650.1 3280354 3280887 R COG3772 Phage-related lysozyme (muraminidase); endolysin complement(3280354..3280887) Escherichia coli O104:H4 str. 2009EL-2050 13689666 YP_006770845.1 CDS O3M_16085 NC_018650.1 3280892 3281107 R holin protein complement(3280892..3281107) Escherichia coli O104:H4 str. 2009EL-2050 13689667 YP_006770846.1 CDS O3M_16090 NC_018650.1 3281185 3281430 R hypothetical protein complement(3281185..3281430) Escherichia coli O104:H4 str. 2009EL-2050 13689668 YP_006770847.1 CDS O3M_16095 NC_018650.1 3281471 3281650 R hypothetical protein complement(3281471..3281650) Escherichia coli O104:H4 str. 2009EL-2050 13689669 YP_006770848.1 CDS O3M_16100 NC_018650.1 3281787 3283724 R hypothetical protein complement(3281787..3283724) Escherichia coli O104:H4 str. 2009EL-2050 13689670 YP_006770849.1 CDS O3M_16105 NC_018650.1 3284210 3284479 R Shiga toxin 2 subunit B complement(3284210..3284479) Escherichia coli O104:H4 str. 2009EL-2050 13689671 YP_006770850.1 CDS O3M_16110 NC_018650.1 3284491 3285450 R Shiga toxin 2 subunit A complement(3284491..3285450) Escherichia coli O104:H4 str. 2009EL-2050 13689672 YP_006770851.1 CDS O3M_16115 NC_018650.1 3285833 3285931 R DNA adenine methyltransferase encoded by prophage complement(3285833..3285931) Escherichia coli O104:H4 str. 2009EL-2050 13689676 YP_006770852.1 CDS O3M_16120 NC_018650.1 3286234 3286668 R antitermination protein Q complement(3286234..3286668) Escherichia coli O104:H4 str. 2009EL-2050 13689677 YP_006770853.1 CDS O3M_16125 NC_018650.1 3286661 3286855 R hypothetical protein complement(3286661..3286855) Escherichia coli O104:H4 str. 2009EL-2050 13689678 YP_006770854.1 CDS O3M_16130 NC_018650.1 3286852 3287415 R hypothetical protein complement(3286852..3287415) Escherichia coli O104:H4 str. 2009EL-2050 13689679 YP_006770855.1 CDS O3M_16135 NC_018650.1 3287423 3287872 R hypothetical protein complement(3287423..3287872) Escherichia coli O104:H4 str. 2009EL-2050 13689680 YP_006770856.1 CDS O3M_16140 NC_018650.1 3287872 3288843 R DNA primase complement(3287872..3288843) Escherichia coli O104:H4 str. 2009EL-2050 13689681 YP_006770857.1 CDS O3M_16145 NC_018650.1 3288833 3290353 R COG1061 DNA or RNA helicases of superfamily II; helicase complement(3288833..3290353) Escherichia coli O104:H4 str. 2009EL-2050 13689682 YP_006770858.1 CDS O3M_16150 NC_018650.1 3290347 3290724 R COG3480 Predicted secreted protein containing a PDZ domain; hypothetical protein complement(3290347..3290724) Escherichia coli O104:H4 str. 2009EL-2050 13689683 YP_006770859.1 CDS O3M_16155 NC_018650.1 3290932 3291225 R hypothetical protein complement(3290932..3291225) Escherichia coli O104:H4 str. 2009EL-2050 13689684 YP_006770860.1 CDS O3M_16160 NC_018650.1 3291256 3291459 R hypothetical protein complement(3291256..3291459) Escherichia coli O104:H4 str. 2009EL-2050 13689685 YP_006770861.1 CDS O3M_16165 NC_018650.1 3291555 3292268 D COG2932 Predicted transcriptional regulator; repressor protein CI 3291555..3292268 Escherichia coli O104:H4 str. 2009EL-2050 13689686 YP_006770862.1 CDS O3M_16170 NC_018650.1 3292363 3293832 D COG0286 Type I restriction-modification system methyltransferase subunit; site-specific DNA-methyltransferase 3292363..3293832 Escherichia coli O104:H4 str. 2009EL-2050 13689687 YP_006770863.1 CDS O3M_16175 NC_018650.1 3293829 3294782 D type II site-specific deoxyribonuclease 3293829..3294782 Escherichia coli O104:H4 str. 2009EL-2050 13689688 YP_006770864.1 CDS O3M_16180 NC_018650.1 3295538 3296185 D COG3646 Uncharacterized phage-encoded protein; hypothetical protein 3295538..3296185 Escherichia coli O104:H4 str. 2009EL-2050 13689689 YP_006770865.1 CDS O3M_16185 NC_018650.1 3296256 3296468 D host killing protein 3296256..3296468 Escherichia coli O104:H4 str. 2009EL-2050 13689690 YP_006770866.1 CDS O3M_16190 NC_018650.1 3296540 3296761 D hypothetical protein 3296540..3296761 Escherichia coli O104:H4 str. 2009EL-2050 13689691 YP_006770867.1 CDS O3M_16195 NC_018650.1 3296782 3297063 D hypothetical protein 3296782..3297063 Escherichia coli O104:H4 str. 2009EL-2050 13689692 YP_006770868.1 CDS O3M_16200 NC_018650.1 3297080 3298030 D COG3723 Recombinational DNA repair protein (RecE pathway); DNA recombination protein Bet 3297080..3298030 Escherichia coli O104:H4 str. 2009EL-2050 13689693 YP_006770869.1 CDS O3M_16205 NC_018650.1 3298027 3298716 D COG4615 ABC-type siderophore export system, fused ATPase and permease components; exonuclease 3298027..3298716 Escherichia coli O104:H4 str. 2009EL-2050 13689694 YP_006770870.1 CDS O3M_16210 NC_018650.1 3298716 3299303 D hypothetical protein 3298716..3299303 Escherichia coli O104:H4 str. 2009EL-2050 13689695 YP_006770871.1 CDS O3M_16215 NC_018650.1 3299378 3299725 D hypothetical protein 3299378..3299725 Escherichia coli O104:H4 str. 2009EL-2050 13689696 YP_006770872.1 CDS O3M_16220 NC_018650.1 3299789 3300610 D COG5532 Uncharacterized conserved protein; hypothetical protein 3299789..3300610 Escherichia coli O104:H4 str. 2009EL-2050 13689697 YP_006770873.1 CDS O3M_16225 NC_018650.1 3300687 3301082 D hypothetical protein 3300687..3301082 Escherichia coli O104:H4 str. 2009EL-2050 13689698 YP_006770874.1 CDS O3M_16230 NC_018650.1 3301233 3301958 D hypothetical protein 3301233..3301958 Escherichia coli O104:H4 str. 2009EL-2050 13689699 YP_006770875.1 CDS O3M_16235 NC_018650.1 3301955 3302362 D hypothetical protein 3301955..3302362 Escherichia coli O104:H4 str. 2009EL-2050 13689700 YP_006770876.1 CDS O3M_16240 NC_018650.1 3302364 3302555 D hypothetical protein 3302364..3302555 Escherichia coli O104:H4 str. 2009EL-2050 13689701 YP_006770877.1 CDS O3M_16245 NC_018650.1 3302558 3303454 D hypothetical protein 3302558..3303454 Escherichia coli O104:H4 str. 2009EL-2050 13689702 YP_006770878.1 CDS O3M_16250 NC_018650.1 3303447 3303545 D hypothetical protein 3303447..3303545 Escherichia coli O104:H4 str. 2009EL-2050 13689703 YP_006770879.1 CDS O3M_16255 NC_018650.1 3303810 3304094 D COG3561 Phage anti-repressor protein; phage anti-repressor protein AntB 3303810..3304094 Escherichia coli O104:H4 str. 2009EL-2050 13689704 YP_006770880.1 CDS O3M_16260 NC_018650.1 3304344 3304973 D COG3561 Phage anti-repressor protein; antirepressor 3304344..3304973 Escherichia coli O104:H4 str. 2009EL-2050 13689705 YP_006770881.1 CDS O3M_16265 NC_018650.1 3305104 3305460 D regulatory protein 3305104..3305460 Escherichia coli O104:H4 str. 2009EL-2050 13689706 YP_006770882.1 CDS O3M_16270 NC_018650.1 3305457 3306083 D COG4725 Transcriptional activator, adenine-specific DNA methyltransferase; adenine methylase 3305457..3306083 Escherichia coli O104:H4 str. 2009EL-2050 13689707 YP_006770883.1 CDS O3M_16275 NC_018650.1 3306043 3306255 D hypothetical protein 3306043..3306255 Escherichia coli O104:H4 str. 2009EL-2050 13689708 YP_006770884.1 CDS O3M_16280 NC_018650.1 3306291 3306671 D hypothetical protein 3306291..3306671 Escherichia coli O104:H4 str. 2009EL-2050 13689709 YP_006770885.1 CDS O3M_16285 NC_018650.1 3307035 3307286 D hypothetical protein 3307035..3307286 Escherichia coli O104:H4 str. 2009EL-2050 13689710 YP_006770886.1 CDS O3M_16290 NC_018650.1 3307332 3307616 D excisionase 3307332..3307616 Escherichia coli O104:H4 str. 2009EL-2050 13689711 YP_006770887.1 CDS O3M_16295 NC_018650.1 3307669 3308979 D COG0582 Integrase; integrase 3307669..3308979 Escherichia coli O104:H4 str. 2009EL-2050 13689712 YP_006770888.1 CDS O3M_16300 NC_018650.1 3308976 3309554 D COG0655 Multimeric flavodoxin WrbA; flavoprotein 3308976..3309554 Escherichia coli O104:H4 str. 2009EL-2050 13689713 YP_006770889.1 CDS O3M_16305 NC_018650.1 3309575 3309802 D hypothetical protein 3309575..3309802 Escherichia coli O104:H4 str. 2009EL-2050 13689714 YP_006770890.1 CDS O3M_16310 NC_018650.1 3309840 3311081 R glucose-1-phosphatase/inositol phosphatase complement(3309840..3311081) Escherichia coli O104:H4 str. 2009EL-2050 13689715 YP_006770891.1 CDS O3M_16315 NC_018650.1 3311370 3312557 R hypothetical protein complement(3311370..3312557) Escherichia coli O104:H4 str. 2009EL-2050 13689716 YP_006770892.1 CDS O3M_16320 NC_018650.1 3312890 3313810 D COG2214 DnaJ-class molecular chaperone; curved DNA-binding protein CbpA 3312890..3313810 Escherichia coli O104:H4 str. 2009EL-2050 13689717 YP_006770893.1 CDS O3M_16325 NC_018650.1 3313810 3314115 D chaperone-modulator protein CbpM 3313810..3314115 Escherichia coli O104:H4 str. 2009EL-2050 13689718 YP_006770894.1 CDS torD NC_018650.1 3314208 3314807 R COG3381 Uncharacterized component of anaerobic dehydrogenases; chaperone protein TorD complement(3314208..3314807) Escherichia coli O104:H4 str. 2009EL-2050 13689719 YP_006770895.1 CDS O3M_16335 NC_018650.1 3314804 3317350 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; trimethylamine N-oxide reductase I catalytic subunit complement(3314804..3317350) Escherichia coli O104:H4 str. 2009EL-2050 13689720 YP_006770896.1 CDS O3M_16340 NC_018650.1 3317350 3318522 R COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; trimethylamine N-oxide reductase cytochrome c-type subunit complement(3317350..3318522) Escherichia coli O104:H4 str. 2009EL-2050 13689721 YP_006770897.1 CDS O3M_16345 NC_018650.1 3318652 3319344 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator TorR 3318652..3319344 Escherichia coli O104:H4 str. 2009EL-2050 13689722 YP_006770898.1 CDS O3M_16350 NC_018650.1 3319317 3320345 R COG1879 ABC-type sugar transport system, periplasmic component; TMAO reductase system periplasmic protein TorT complement(3319317..3320345) Escherichia coli O104:H4 str. 2009EL-2050 13689723 YP_006770899.1 CDS O3M_16355 NC_018650.1 3320428 3323172 D COG0642 Signal transduction histidine kinase; hybrid sensory histidine kinase TorS 3320428..3323172 Escherichia coli O104:H4 str. 2009EL-2050 13689724 YP_006770900.1 CDS O3M_16360 NC_018650.1 3323244 3324317 D COG0348 Polyferredoxin; 4Fe-4S binding protein 3323244..3324317 Escherichia coli O104:H4 str. 2009EL-2050 13689725 YP_006770901.1 CDS O3M_16365 NC_018650.1 3324366 3324539 R regulator of phosphatidylethanolamine synthesis complement(3324366..3324539) Escherichia coli O104:H4 str. 2009EL-2050 13689726 YP_006770902.1 CDS O3M_16370 NC_018650.1 3324529 3324792 R cold shock protein complement(3324529..3324792) Escherichia coli O104:H4 str. 2009EL-2050 13689727 YP_006770903.1 CDS O3M_16375 NC_018650.1 3324933 3325145 R COG1278 Cold shock proteins; cold shock protein CspG complement(3324933..3325145) Escherichia coli O104:H4 str. 2009EL-2050 13689728 YP_006770904.1 CDS O3M_16380 NC_018650.1 3325431 3325643 D COG1278 Cold shock proteins; cold shock-like protein CspH 3325431..3325643 Escherichia coli O104:H4 str. 2009EL-2050 13689729 YP_006770905.1 CDS O3M_16385 NC_018650.1 3326497 3327141 D outer membrane lipoprotein 3326497..3327141 Escherichia coli O104:H4 str. 2009EL-2050 13689730 YP_006770906.1 CDS O3M_16390 NC_018650.1 3327138 3327884 D hypothetical protein 3327138..3327884 Escherichia coli O104:H4 str. 2009EL-2050 13689731 YP_006770907.1 CDS O3M_16395 NC_018650.1 3327884 3329980 D hypothetical protein 3327884..3329980 Escherichia coli O104:H4 str. 2009EL-2050 13689732 YP_006770908.1 CDS O3M_16400 NC_018650.1 3330026 3331165 D COG1596 Periplasmic protein involved in polysaccharide export; polysaccharide export protein Wza 3330026..3331165 Escherichia coli O104:H4 str. 2009EL-2050 13689733 YP_006770909.1 CDS etp NC_018650.1 3331153 3331599 D COG0394 Protein-tyrosine-phosphatase; phosphotyrosine-protein phosphatase 3331153..3331599 Escherichia coli O104:H4 str. 2009EL-2050 13689734 YP_006770910.1 CDS O3M_16410 NC_018650.1 3331619 3333799 D COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; cryptic autophosphorylating protein tyrosine kinase Etk 3331619..3333799 Escherichia coli O104:H4 str. 2009EL-2050 13689735 YP_006770911.1 CDS O3M_16415 NC_018650.1 3333914 3335212 R phosphoanhydride phosphorylase complement(3333914..3335212) Escherichia coli O104:H4 str. 2009EL-2050 13689736 YP_006770912.1 CDS O3M_16420 NC_018650.1 3335292 3335384 R hypothetical protein complement(3335292..3335384) Escherichia coli O104:H4 str. 2009EL-2050 13689737 YP_006770913.1 CDS O3M_16425 NC_018650.1 3335397 3336533 R COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome bd-II oxidase subunit 2 complement(3335397..3336533) Escherichia coli O104:H4 str. 2009EL-2050 13689738 YP_006770914.1 CDS O3M_16430 NC_018650.1 3336545 3338089 R COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome bd-II oxidase subunit 1 complement(3336545..3338089) Escherichia coli O104:H4 str. 2009EL-2050 13689739 YP_006770915.1 CDS O3M_16435 NC_018650.1 3338223 3339080 R hydrogenase-1 operon protein HyaF complement(3338223..3339080) Escherichia coli O104:H4 str. 2009EL-2050 13689740 YP_006770916.1 CDS O3M_16440 NC_018650.1 3339077 3339475 R COG0526 Thiol-disulfide isomerase and thioredoxins; hydrogenase-1 operon protein HyaE complement(3339077..3339475) Escherichia coli O104:H4 str. 2009EL-2050 13689741 YP_006770917.1 CDS O3M_16445 NC_018650.1 3339472 3340059 R COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 1 maturation protease complement(3339472..3340059) Escherichia coli O104:H4 str. 2009EL-2050 13689742 YP_006770918.1 CDS O3M_16450 NC_018650.1 3340056 3340763 R COG1969 Ni,Fe-hydrogenase I cytochrome b subunit; hydrogenase 1 b-type cytochrome subunit complement(3340056..3340763) Escherichia coli O104:H4 str. 2009EL-2050 13689743 YP_006770919.1 CDS O3M_16455 NC_018650.1 3340782 3342575 R COG0374 Ni,Fe-hydrogenase I large subunit; hydrogenase 1 large subunit complement(3340782..3342575) Escherichia coli O104:H4 str. 2009EL-2050 13689744 YP_006770920.1 CDS O3M_16460 NC_018650.1 3342572 3343690 R COG1740 Ni,Fe-hydrogenase I small subunit; hydrogenase 1, small subunit complement(3342572..3343690) Escherichia coli O104:H4 str. 2009EL-2050 13689745 YP_006770921.1 CDS O3M_16465 NC_018650.1 3344411 3345070 D COG0670 Integral membrane protein, interacts with FtsH; HflBKC-binding inner membrane protein 3344411..3345070 Escherichia coli O104:H4 str. 2009EL-2050 13689747 YP_006770922.1 CDS O3M_16470 NC_018650.1 3345161 3345490 D COG2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit; sulfur transfer protein TusE 3345161..3345490 Escherichia coli O104:H4 str. 2009EL-2050 13689748 YP_006770923.1 CDS O3M_16475 NC_018650.1 3345487 3345765 R COG1254 Acylphosphatases; acylphosphatase complement(3345487..3345765) Escherichia coli O104:H4 str. 2009EL-2050 13689749 YP_006770924.1 CDS O3M_16480 NC_018650.1 3345860 3347050 D COG1092 Predicted SAM-dependent methyltransferases; 23S rRNA m(5)C1962 methyltransferase 3345860..3347050 Escherichia coli O104:H4 str. 2009EL-2050 13689750 YP_006770925.1 CDS O3M_16485 NC_018650.1 3347108 3347425 D COG3785 Uncharacterized conserved protein; heat shock protein HspQ 3347108..3347425 Escherichia coli O104:H4 str. 2009EL-2050 13689751 YP_006770926.1 CDS O3M_16490 NC_018650.1 3347470 3347883 R COG1832 Predicted CoA-binding protein; hypothetical protein complement(3347470..3347883) Escherichia coli O104:H4 str. 2009EL-2050 13689752 YP_006770927.1 CDS O3M_16495 NC_018650.1 3348056 3348718 D COG3110 Uncharacterized protein conserved in bacteria; hypothetical protein 3348056..3348718 Escherichia coli O104:H4 str. 2009EL-2050 13689753 YP_006770928.1 CDS mgsA NC_018650.1 3348814 3349272 D COG1803 Methylglyoxal synthase; methylglyoxal synthase 3348814..3349272 Escherichia coli O104:H4 str. 2009EL-2050 13689754 YP_006770929.1 CDS helD NC_018650.1 3349304 3351358 R COG0210 Superfamily I DNA and RNA helicases; DNA helicase IV complement(3349304..3351358) Escherichia coli O104:H4 str. 2009EL-2050 13689755 YP_006770930.1 CDS O3M_16510 NC_018650.1 3351481 3351927 D COG3304 Predicted membrane protein; hypothetical protein 3351481..3351927 Escherichia coli O104:H4 str. 2009EL-2050 13689756 YP_006770931.1 CDS O3M_16515 NC_018650.1 3351937 3354099 D COG1289 Predicted membrane protein; hypothetical protein 3351937..3354099 Escherichia coli O104:H4 str. 2009EL-2050 13689757 YP_006770932.1 CDS O3M_16520 NC_018650.1 3354062 3354691 R COG3070 Regulator of competence-specific genes; hypothetical protein complement(3354062..3354691) Escherichia coli O104:H4 str. 2009EL-2050 13689758 YP_006770933.1 CDS O3M_16525 NC_018650.1 3354910 3355419 D COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation; SOS cell division inhibitor 3354910..3355419 Escherichia coli O104:H4 str. 2009EL-2050 13689759 YP_006770934.1 CDS O3M_16530 NC_018650.1 3355776 3356816 D COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; outer membrane protein A 3355776..3356816 Escherichia coli O104:H4 str. 2009EL-2050 13689760 YP_006770935.1 CDS O3M_16535 NC_018650.1 3356892 3357344 R COG3120 Uncharacterized protein conserved in bacteria; Ter macrodomain organizer matS-binding protein complement(3356892..3357344) Escherichia coli O104:H4 str. 2009EL-2050 13689761 YP_006770936.1 CDS O3M_16540 NC_018650.1 3357530 3359290 D COG1067 Predicted ATP-dependent protease; peptidase, S16 (Lon protease) family protein 3357530..3359290 Escherichia coli O104:H4 str. 2009EL-2050 13689762 YP_006770937.1 CDS O3M_16545 NC_018650.1 3359359 3359877 D COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; 3-hydroxydecanoyl-ACP dehydratase 3359359..3359877 Escherichia coli O104:H4 str. 2009EL-2050 13689763 YP_006770938.1 CDS O3M_16550 NC_018650.1 3359947 3360114 R COG3130 Ribosome modulation factor; ribosome modulation factor complement(3359947..3360114) Escherichia coli O104:H4 str. 2009EL-2050 13689764 YP_006770939.1 CDS O3M_16555 NC_018650.1 3360370 3360933 R COG3009 Uncharacterized protein conserved in bacteria; lipoprotein complement(3360370..3360933) Escherichia coli O104:H4 str. 2009EL-2050 13689765 YP_006770940.1 CDS O3M_16560 NC_018650.1 3360930 3362570 R COG3008 Paraquat-inducible protein B; paraquat-inducible protein B complement(3360930..3362570) Escherichia coli O104:H4 str. 2009EL-2050 13689766 YP_006770941.1 CDS O3M_16565 NC_018650.1 3362575 3363828 R COG2995 Uncharacterized paraquat-inducible protein A; paraquat-inducible membrane protein A complement(3362575..3363828) Escherichia coli O104:H4 str. 2009EL-2050 13689767 YP_006770942.1 CDS O3M_16570 NC_018650.1 3363958 3365865 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase complement(3363958..3365865) Escherichia coli O104:H4 str. 2009EL-2050 13689768 YP_006770943.1 CDS rlmL NC_018650.1 3365876 3367984 R COG0116 Predicted N6-adenine-specific DNA methylase; 23S rRNA m(2)G2445 methyltransferase complement(3365876..3367984) Escherichia coli O104:H4 str. 2009EL-2050 13689769 YP_006770944.1 CDS O3M_16580 NC_018650.1 3368228 3369337 D COG3217 Uncharacterized Fe-S protein; 2Fe-2S cluster-containing protein 3368228..3369337 Escherichia coli O104:H4 str. 2009EL-2050 13689770 YP_006770945.1 CDS O3M_16585 NC_018650.1 3369334 3369876 R hypothetical protein complement(3369334..3369876) Escherichia coli O104:H4 str. 2009EL-2050 13689771 YP_006770946.1 CDS O3M_16590 NC_018650.1 3370050 3371060 R COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 2 complement(3370050..3371060) Escherichia coli O104:H4 str. 2009EL-2050 13689772 YP_006770947.1 CDS O3M_16595 NC_018650.1 3371171 3371881 R COG3121 P pilus assembly protein, chaperone PapD; pili assembly chaperone complement(3371171..3371881) Escherichia coli O104:H4 str. 2009EL-2050 13689773 YP_006770948.1 CDS O3M_16600 NC_018650.1 3371874 3372389 R COG3539 P pilus assembly protein, pilin FimA; fimbrial protein complement(3371874..3372389) Escherichia coli O104:H4 str. 2009EL-2050 13689774 YP_006770949.1 CDS O3M_16605 NC_018650.1 3372397 3372939 R COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein complement(3372397..3372939) Escherichia coli O104:H4 str. 2009EL-2050 13689775 YP_006770950.1 CDS O3M_16610 NC_018650.1 3372951 3374021 R fimbrial-like adhesin protein complement(3372951..3374021) Escherichia coli O104:H4 str. 2009EL-2050 13689776 YP_006770951.1 CDS O3M_16615 NC_018650.1 3374012 3376612 R COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein complement(3374012..3376612) Escherichia coli O104:H4 str. 2009EL-2050 13689777 YP_006770952.1 CDS O3M_16620 NC_018650.1 3376637 3377338 R COG3121 P pilus assembly protein, chaperone PapD; periplasmic pilin chaperone complement(3376637..3377338) Escherichia coli O104:H4 str. 2009EL-2050 13689778 YP_006770953.1 CDS O3M_16625 NC_018650.1 3377421 3377963 R COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein complement(3377421..3377963) Escherichia coli O104:H4 str. 2009EL-2050 13689779 YP_006770954.1 CDS O3M_16630 NC_018650.1 3378319 3378894 D COG0431 Predicted flavoprotein; NAD(P)H-dependent FMN reductase 3378319..3378894 Escherichia coli O104:H4 str. 2009EL-2050 13689780 YP_006770955.1 CDS O3M_16635 NC_018650.1 3378887 3379846 D COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; alkanesulfonate transporter substrate-binding subunit 3378887..3379846 Escherichia coli O104:H4 str. 2009EL-2050 13689781 YP_006770956.1 CDS O3M_16640 NC_018650.1 3379843 3380988 D COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkanesulfonate monooxygenase 3379843..3380988 Escherichia coli O104:H4 str. 2009EL-2050 13689782 YP_006770957.1 CDS ssuC NC_018650.1 3380999 3381790 D COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; alkanesulfonate transporter permease 3380999..3381790 Escherichia coli O104:H4 str. 2009EL-2050 13689783 YP_006770958.1 CDS ssuB NC_018650.1 3381787 3382554 D COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; aliphatic sulfonates transport ATP-binding subunit 3381787..3382554 Escherichia coli O104:H4 str. 2009EL-2050 13689784 YP_006770959.1 CDS pepN NC_018650.1 3382761 3385373 R COG0308 Aminopeptidase N; aminopeptidase N complement(3382761..3385373) Escherichia coli O104:H4 str. 2009EL-2050 13689785 YP_006770960.1 CDS O3M_16660 NC_018650.1 3385639 3386841 D COG1488 Nicotinic acid phosphoribosyltransferase; nicotinate phosphoribosyltransferase 3385639..3386841 Escherichia coli O104:H4 str. 2009EL-2050 13689786 YP_006770961.1 CDS asnC NC_018650.1 3387010 3388410 D COG0017 Aspartyl/asparaginyl-tRNA synthetases; asparaginyl-tRNA synthetase 3387010..3388410 Escherichia coli O104:H4 str. 2009EL-2050 13689787 YP_006770962.1 CDS O3M_16670 NC_018650.1 3389012 3390100 D COG3203 Outer membrane protein (porin); outer membrane protein F 3389012..3390100 Escherichia coli O104:H4 str. 2009EL-2050 13689788 YP_006770963.1 CDS O3M_16675 NC_018650.1 3390116 3390286 R hypothetical protein complement(3390116..3390286) Escherichia coli O104:H4 str. 2009EL-2050 13689789 YP_006770964.1 CDS O3M_16680 NC_018650.1 3390285 3391475 D COG1448 Aspartate/tyrosine/aromatic aminotransferase; aromatic amino acid aminotransferase 3390285..3391475 Escherichia coli O104:H4 str. 2009EL-2050 13689790 YP_006770965.1 CDS O3M_16685 NC_018650.1 3391754 3392734 D COG3547 Transposase and inactivated derivatives; IS621 transposase 3391754..3392734 Escherichia coli O104:H4 str. 2009EL-2050 13689791 YP_006770966.1 CDS O3M_16690 NC_018650.1 3392976 3393623 R COG0491 Zn-dependent hydrolases, including glyoxylases; metal-binding enzyme complement(3392976..3393623) Escherichia coli O104:H4 str. 2009EL-2050 13689792 YP_006770967.1 CDS O3M_16695 NC_018650.1 3393650 3394198 R COG3108 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3393650..3394198) Escherichia coli O104:H4 str. 2009EL-2050 13689793 YP_006770968.1 CDS O3M_16700 NC_018650.1 3394379 3396226 R COG2989 Uncharacterized protein conserved in bacteria; murein L,D-transpeptidase complement(3394379..3396226) Escherichia coli O104:H4 str. 2009EL-2050 13689794 YP_006770969.1 CDS mukB NC_018650.1 3396487 3400947 R COG3096 Uncharacterized protein involved in chromosome partitioning; cell division protein MukB complement(3396487..3400947) Escherichia coli O104:H4 str. 2009EL-2050 13689795 YP_006770970.1 CDS O3M_16710 NC_018650.1 3400947 3401651 R COG3095 Uncharacterized protein involved in chromosome partitioning; condesin subunit E complement(3400947..3401651) Escherichia coli O104:H4 str. 2009EL-2050 13689796 YP_006770971.1 CDS O3M_16715 NC_018650.1 3401632 3402954 R COG3006 Uncharacterized protein involved in chromosome partitioning; condesin subunit F complement(3401632..3402954) Escherichia coli O104:H4 str. 2009EL-2050 13689797 YP_006770972.1 CDS O3M_16720 NC_018650.1 3402951 3403736 R COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase complement(3402951..3403736) Escherichia coli O104:H4 str. 2009EL-2050 13689798 YP_006770973.1 CDS O3M_16725 NC_018650.1 3403872 3404651 D COG1434 Uncharacterized conserved protein; hypothetical protein 3403872..3404651 Escherichia coli O104:H4 str. 2009EL-2050 13689799 YP_006770974.1 CDS O3M_16730 NC_018650.1 3404628 3405521 R hypothetical protein complement(3404628..3405521) Escherichia coli O104:H4 str. 2009EL-2050 13689800 YP_006770975.1 CDS O3M_16735 NC_018650.1 3405675 3406421 R COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; 3-deoxy-manno-octulosonate cytidylyltransferase complement(3405675..3406421) Escherichia coli O104:H4 str. 2009EL-2050 13689801 YP_006770976.1 CDS O3M_16740 NC_018650.1 3406418 3406600 R COG2835 Uncharacterized conserved protein; hypothetical protein complement(3406418..3406600) Escherichia coli O104:H4 str. 2009EL-2050 13689802 YP_006770977.1 CDS O3M_16745 NC_018650.1 3406652 3407884 R COG3214 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3406652..3407884) Escherichia coli O104:H4 str. 2009EL-2050 13689803 YP_006770978.1 CDS lpxK NC_018650.1 3407921 3408907 R COG1663 Tetraacyldisaccharide-1-P 4'-kinase; tetraacyldisaccharide 4'-kinase complement(3407921..3408907) Escherichia coli O104:H4 str. 2009EL-2050 13689804 YP_006770979.1 CDS O3M_16755 NC_018650.1 3408904 3410652 R COG1132 ABC-type multidrug transport system, ATPase and permease components; lipid transporter ATP-binding protein/permease complement(3408904..3410652) Escherichia coli O104:H4 str. 2009EL-2050 13689805 YP_006770980.1 CDS O3M_16760 NC_018650.1 3410689 3412953 R COG0658 Predicted membrane metal-binding protein; ComEC family competence protein complement(3410689..3412953) Escherichia coli O104:H4 str. 2009EL-2050 13689806 YP_006770981.1 CDS ihfB NC_018650.1 3413160 3413444 R COG0776 Bacterial nucleoid DNA-binding protein; integration host factor subunit beta complement(3413160..3413444) Escherichia coli O104:H4 str. 2009EL-2050 13689807 YP_006770982.1 CDS rpsA NC_018650.1 3413604 3415277 R COG0539 Ribosomal protein S1; 30S ribosomal protein S1 complement(3413604..3415277) Escherichia coli O104:H4 str. 2009EL-2050 13689808 YP_006770983.1 CDS cmk NC_018650.1 3415388 3416071 R COG0283 Cytidylate kinase; cytidylate kinase complement(3415388..3416071) Escherichia coli O104:H4 str. 2009EL-2050 13689809 YP_006770984.1 CDS O3M_16780 NC_018650.1 3416244 3417008 R COG0501 Zn-dependent protease with chaperone function; heat shock protein complement(3416244..3417008) Escherichia coli O104:H4 str. 2009EL-2050 13689810 YP_006770985.1 CDS O3M_16785 NC_018650.1 3417177 3418460 R COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase complement(3417177..3418460) Escherichia coli O104:H4 str. 2009EL-2050 13689811 YP_006770986.1 CDS O3M_16790 NC_018650.1 3418531 3419619 R COG1932 Phosphoserine aminotransferase; 3-phosphoserine/phosphohydroxythreonine aminotransferase complement(3418531..3419619) Escherichia coli O104:H4 str. 2009EL-2050 13689812 YP_006770987.1 CDS O3M_16795 NC_018650.1 3419818 3420510 R COG2323 Predicted membrane protein; hypothetical protein complement(3419818..3420510) Escherichia coli O104:H4 str. 2009EL-2050 13689813 YP_006770988.1 CDS O3M_16800 NC_018650.1 3420640 3422400 D COG1944 Uncharacterized conserved protein; hypothetical protein 3420640..3422400 Escherichia coli O104:H4 str. 2009EL-2050 13689814 YP_006770989.1 CDS O3M_16805 NC_018650.1 3422805 3423662 D COG2116 Formate/nitrite family of transporters; formate transporter 3422805..3423662 Escherichia coli O104:H4 str. 2009EL-2050 13689815 YP_006770990.1 CDS O3M_16810 NC_018650.1 3423717 3425999 D COG1882 Pyruvate-formate lyase; formate acetyltransferase 3423717..3425999 Escherichia coli O104:H4 str. 2009EL-2050 13689816 YP_006770991.1 CDS pflA NC_018650.1 3426191 3426931 D COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase-activating enzyme 1 3426191..3426931 Escherichia coli O104:H4 str. 2009EL-2050 13689817 YP_006770992.1 CDS O3M_16820 NC_018650.1 3427013 3427603 R COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); hypothetical protein complement(3427013..3427603) Escherichia coli O104:H4 str. 2009EL-2050 13689818 YP_006770993.1 CDS O3M_16825 NC_018650.1 3427703 3428611 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 3427703..3428611 Escherichia coli O104:H4 str. 2009EL-2050 13689819 YP_006770994.1 CDS O3M_16830 NC_018650.1 3428612 3430042 R COG0531 Amino acid transporters; transporter complement(3428612..3430042) Escherichia coli O104:H4 str. 2009EL-2050 13689820 YP_006770995.1 CDS O3M_16835 NC_018650.1 3430252 3431400 R COG0477 Permeases of the major facilitator superfamily; MFS family transporter protein complement(3430252..3431400) Escherichia coli O104:H4 str. 2009EL-2050 13689821 YP_006770996.1 CDS O3M_16840 NC_018650.1 3431714 3432340 D COG1335 Amidases related to nicotinamidase; hydrolase 3431714..3432340 Escherichia coli O104:H4 str. 2009EL-2050 13689822 YP_006770997.1 CDS O3M_16845 NC_018650.1 3432376 3433239 R COG3302 DMSO reductase anchor subunit; dimethyl sulfoxide reductase, anaerobic subunit C complement(3432376..3433239) Escherichia coli O104:H4 str. 2009EL-2050 13689823 YP_006770998.1 CDS O3M_16850 NC_018650.1 3433241 3433858 R COG0437 Fe-S-cluster-containing hydrogenase components 1; anaerobic dimethyl sulfoxide reductase subunit B complement(3433241..3433858) Escherichia coli O104:H4 str. 2009EL-2050 13689824 YP_006770999.1 CDS O3M_16855 NC_018650.1 3433869 3436313 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; anaerobic dimethyl sulfoxide reductase subunit A complement(3433869..3436313) Escherichia coli O104:H4 str. 2009EL-2050 13689825 YP_006771000.1 CDS O3M_16860 NC_018650.1 3436552 3437844 R COG0172 Seryl-tRNA synthetase; seryl-tRNA synthetase complement(3436552..3437844) Escherichia coli O104:H4 str. 2009EL-2050 13689826 YP_006771001.1 CDS O3M_16865 NC_018650.1 3437935 3439278 R COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA complement(3437935..3439278) Escherichia coli O104:H4 str. 2009EL-2050 13689827 YP_006771002.1 CDS lolA NC_018650.1 3439289 3439900 R COG2834 Outer membrane lipoprotein-sorting protein; lipoprotein chaperone complement(3439289..3439900) Escherichia coli O104:H4 str. 2009EL-2050 13689828 YP_006771003.1 CDS O3M_16875 NC_018650.1 3440055 3444122 R COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA translocase FtsK complement(3440055..3444122) Escherichia coli O104:H4 str. 2009EL-2050 13689829 YP_006771004.1 CDS O3M_16880 NC_018650.1 3444257 3444751 R COG1522 Transcriptional regulators; leucine-responsive transcriptional regulator complement(3444257..3444751) Escherichia coli O104:H4 str. 2009EL-2050 13689830 YP_006771005.1 CDS O3M_16885 NC_018650.1 3445296 3446261 D COG0492 Thioredoxin reductase; thioredoxin reductase 3445296..3446261 Escherichia coli O104:H4 str. 2009EL-2050 13689831 YP_006771006.1 CDS O3M_16890 NC_018650.1 3446384 3448150 D COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; cysteine/glutathione ABC transporter membrane/ATP-binding protein 3446384..3448150 Escherichia coli O104:H4 str. 2009EL-2050 13689832 YP_006771007.1 CDS O3M_16895 NC_018650.1 3448151 3449872 D COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components; cysteine/glutathione ABC transporter membrane/ATP-binding protein 3448151..3449872 Escherichia coli O104:H4 str. 2009EL-2050 13689833 YP_006771008.1 CDS aat NC_018650.1 3449914 3450618 D COG2360 Leu/Phe-tRNA-protein transferase; leucyl/phenylalanyl-tRNA--protein transferase 3449914..3450618 Escherichia coli O104:H4 str. 2009EL-2050 13689834 YP_006771009.1 CDS infA NC_018650.1 3450903 3451121 D COG0361 Translation initiation factor 1 (IF-1); translation initiation factor IF-1 3450903..3451121 Escherichia coli O104:H4 str. 2009EL-2050 13689835 YP_006771010.1 CDS clpA NC_018650.1 3451806 3454082 R COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit complement(3451806..3454082) Escherichia coli O104:H4 str. 2009EL-2050 13689837 YP_006771011.1 CDS clpS NC_018650.1 3454113 3454433 R COG2127 Uncharacterized conserved protein; ATP-dependent Clp protease adaptor protein ClpS complement(3454113..3454433) Escherichia coli O104:H4 str. 2009EL-2050 13689838 YP_006771012.1 CDS O3M_16920 NC_018650.1 3454756 3454980 D COG1278 Cold shock proteins; stationary phase/starvation inducible regulatory protein CspD 3454756..3454980 Escherichia coli O104:H4 str. 2009EL-2050 13689839 YP_006771013.1 CDS O3M_16925 NC_018650.1 3455053 3456999 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; macrolide transporter ATP-binding /permease complement(3455053..3456999) Escherichia coli O104:H4 str. 2009EL-2050 13689840 YP_006771014.1 CDS O3M_16930 NC_018650.1 3456996 3458111 R COG0845 Membrane-fusion protein; macrolide transporter subunit MacA complement(3456996..3458111) Escherichia coli O104:H4 str. 2009EL-2050 13689841 YP_006771015.1 CDS O3M_16935 NC_018650.1 3458226 3459218 D COG2990 Uncharacterized protein conserved in bacteria; hypothetical protein 3458226..3459218 Escherichia coli O104:H4 str. 2009EL-2050 13689842 YP_006771016.1 CDS O3M_16940 NC_018650.1 3459215 3460873 R COG3593 Predicted ATP-dependent endonuclease of the OLD family; OLD family ATP-dependent endonuclease complement(3459215..3460873) Escherichia coli O104:H4 str. 2009EL-2050 13689843 YP_006771017.1 CDS O3M_16945 NC_018650.1 3461299 3461994 D COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); aquaporin Z 3461299..3461994 Escherichia coli O104:H4 str. 2009EL-2050 13689844 YP_006771018.1 CDS O3M_16950 NC_018650.1 3462489 3463388 D COG2431 Predicted membrane protein; transporter 3462489..3463388 Escherichia coli O104:H4 str. 2009EL-2050 13689845 YP_006771019.1 CDS O3M_16955 NC_018650.1 3463532 3465184 D COG1151 6Fe-6S prismane cluster-containing protein; hybrid cluster protein 3463532..3465184 Escherichia coli O104:H4 str. 2009EL-2050 13689846 YP_006771020.1 CDS O3M_16960 NC_018650.1 3465196 3466164 D COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; HCP oxidoreductase 3465196..3466164 Escherichia coli O104:H4 str. 2009EL-2050 13689847 YP_006771021.1 CDS O3M_16965 NC_018650.1 3466297 3468015 D COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; pyruvate dehydrogenase 3466297..3468015 Escherichia coli O104:H4 str. 2009EL-2050 13689848 YP_006771022.1 CDS O3M_16970 NC_018650.1 3468052 3469053 D COG2008 Threonine aldolase; L-threonine aldolase 3468052..3469053 Escherichia coli O104:H4 str. 2009EL-2050 13689849 YP_006771023.1 CDS O3M_16975 NC_018650.1 3469064 3470494 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 3469064..3470494 Escherichia coli O104:H4 str. 2009EL-2050 13689850 YP_006771024.1 CDS O3M_16980 NC_018650.1 3470593 3471606 D COG0451 Nucleoside-diphosphate-sugar epimerases; NAD dependent epimerase/dehydratase family protein 3470593..3471606 Escherichia coli O104:H4 str. 2009EL-2050 13689851 YP_006771025.1 CDS O3M_16985 NC_018650.1 3471603 3472433 R COG3023 Negative regulator of beta-lactamase expression; N-acetylmuramoyl-L-alanine amidase AmiD complement(3471603..3472433) Escherichia coli O104:H4 str. 2009EL-2050 13689852 YP_006771026.1 CDS O3M_16990 NC_018650.1 3472430 3472753 R COG0393 Uncharacterized conserved protein; hypothetical protein complement(3472430..3472753) Escherichia coli O104:H4 str. 2009EL-2050 13689853 YP_006771027.1 CDS O3M_16995 NC_018650.1 3472879 3473394 D COG0174 Glutamine synthetase; lipoprotein 3472879..3473394 Escherichia coli O104:H4 str. 2009EL-2050 13689854 YP_006771028.1 CDS artP NC_018650.1 3473612 3474340 D COG4161 ABC-type arginine transport system, ATPase component; arginine transporter ATP-binding subunit 3473612..3474340 Escherichia coli O104:H4 str. 2009EL-2050 13689855 YP_006771029.1 CDS O3M_17005 NC_018650.1 3474358 3475089 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; arginine ABC transporter substrate-binding protein 3474358..3475089 Escherichia coli O104:H4 str. 2009EL-2050 13689856 YP_006771030.1 CDS O3M_17010 NC_018650.1 3475096 3475812 D COG4215 ABC-type arginine transport system, permease component; arginine transporter permease subunit ArtQ 3475096..3475812 Escherichia coli O104:H4 str. 2009EL-2050 13689857 YP_006771031.1 CDS artM NC_018650.1 3475812 3476480 D COG4160 ABC-type arginine/histidine transport system, permease component; arginine transporter permease subunit ArtM 3475812..3476480 Escherichia coli O104:H4 str. 2009EL-2050 13689858 YP_006771032.1 CDS O3M_17020 NC_018650.1 3476772 3477503 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; arginine 3rd transport system periplasmic binding protein ArtJ 3476772..3477503 Escherichia coli O104:H4 str. 2009EL-2050 13689859 YP_006771033.1 CDS rumB NC_018650.1 3477678 3478805 R COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; 23S rRNA methyluridine methyltransferase complement(3477678..3478805) Escherichia coli O104:H4 str. 2009EL-2050 13689860 YP_006771034.1 CDS O3M_17030 NC_018650.1 3478846 3479334 R inner membrane protein complement(3478846..3479334) Escherichia coli O104:H4 str. 2009EL-2050 13689861 YP_006771035.1 CDS O3M_17035 NC_018650.1 3479394 3480239 R COG1177 ABC-type spermidine/putrescine transport system, permease component II; putrescine ABC transporter permease complement(3479394..3480239) Escherichia coli O104:H4 str. 2009EL-2050 13689862 YP_006771036.1 CDS O3M_17040 NC_018650.1 3480236 3481189 R COG1176 ABC-type spermidine/putrescine transport system, permease component I; putrescine ABC transporter permease complement(3480236..3481189) Escherichia coli O104:H4 str. 2009EL-2050 13689863 YP_006771037.1 CDS potG NC_018650.1 3481199 3482332 R COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; putrescine ABC transporter ATP-binding protein complement(3481199..3482332) Escherichia coli O104:H4 str. 2009EL-2050 13689864 YP_006771038.1 CDS O3M_17050 NC_018650.1 3482427 3483539 R COG0687 Spermidine/putrescine-binding periplasmic protein; putrescine ABC transporter substrate-binding protein complement(3482427..3483539) Escherichia coli O104:H4 str. 2009EL-2050 13689865 YP_006771039.1 CDS O3M_17055 NC_018650.1 3483891 3484367 R sensory transduction regulator complement(3483891..3484367) Escherichia coli O104:H4 str. 2009EL-2050 13689866 YP_006771040.1 CDS O3M_17060 NC_018650.1 3484455 3485357 R COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); ribosomal protein S6 modification protein complement(3484455..3485357) Escherichia coli O104:H4 str. 2009EL-2050 13689867 YP_006771041.1 CDS O3M_17065 NC_018650.1 3485418 3486140 R COG0778 Nitroreductase; nitroreductase A complement(3485418..3486140) Escherichia coli O104:H4 str. 2009EL-2050 13689868 YP_006771042.1 CDS O3M_17070 NC_018650.1 3486124 3486411 R hypothetical protein complement(3486124..3486411) Escherichia coli O104:H4 str. 2009EL-2050 13689869 YP_006771043.1 CDS grxA NC_018650.1 3486571 3486828 D COG0695 Glutaredoxin and related proteins; glutaredoxin 3486571..3486828 Escherichia coli O104:H4 str. 2009EL-2050 13689870 YP_006771044.1 CDS O3M_17080 NC_018650.1 3486858 3487235 R hypothetical protein complement(3486858..3487235) Escherichia coli O104:H4 str. 2009EL-2050 13689871 YP_006771045.1 CDS O3M_17085 NC_018650.1 3487505 3489190 D COG2985 Predicted permease; transporter 3487505..3489190 Escherichia coli O104:H4 str. 2009EL-2050 13689872 YP_006771046.1 CDS O3M_17090 NC_018650.1 3489365 3489901 R COG3226 Uncharacterized protein conserved in bacteria; DNA-binding transcriptional regulator complement(3489365..3489901) Escherichia coli O104:H4 str. 2009EL-2050 13689873 YP_006771047.1 CDS O3M_17095 NC_018650.1 3489985 3491193 D COG0477 Permeases of the major facilitator superfamily; transporter 3489985..3491193 Escherichia coli O104:H4 str. 2009EL-2050 13689874 YP_006771048.1 CDS O3M_17100 NC_018650.1 3491193 3492008 D COG0561 Predicted hydrolases of the HAD superfamily; phosphatase 3491193..3492008 Escherichia coli O104:H4 str. 2009EL-2050 13689875 YP_006771049.1 CDS O3M_17105 NC_018650.1 3492094 3492378 D hypothetical protein 3492094..3492378 Escherichia coli O104:H4 str. 2009EL-2050 13689876 YP_006771050.1 CDS O3M_17110 NC_018650.1 3492419 3493651 R COG0477 Permeases of the major facilitator superfamily; multidrug efflux system translocase MdfA complement(3492419..3493651) Escherichia coli O104:H4 str. 2009EL-2050 13689877 YP_006771051.1 CDS O3M_17115 NC_018650.1 3493936 3494532 D COG0671 Membrane-associated phospholipid phosphatase; undecaprenyl pyrophosphate phosphatase 3493936..3494532 Escherichia coli O104:H4 str. 2009EL-2050 13689878 YP_006771052.1 CDS O3M_17120 NC_018650.1 3494590 3495348 D COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor DeoR 3494590..3495348 Escherichia coli O104:H4 str. 2009EL-2050 13689879 YP_006771053.1 CDS O3M_17125 NC_018650.1 3495395 3496597 R COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase complement(3495395..3496597) Escherichia coli O104:H4 str. 2009EL-2050 13689880 YP_006771054.1 CDS O3M_17130 NC_018650.1 3496844 3497470 D COG0625 Glutathione S-transferase; transferase 3496844..3497470 Escherichia coli O104:H4 str. 2009EL-2050 13689881 YP_006771055.1 CDS O3M_17135 NC_018650.1 3497467 3498582 R COG2133 Glucose/sorbosone dehydrogenases; dehydrogenase complement(3497467..3498582) Escherichia coli O104:H4 str. 2009EL-2050 13689882 YP_006771056.1 CDS bssR NC_018650.1 3498693 3499076 R biofilm formation regulatory protein BssR complement(3498693..3499076) Escherichia coli O104:H4 str. 2009EL-2050 13689883 YP_006771057.1 CDS rimO NC_018650.1 3499289 3500614 D COG0621 2-methylthioadenine synthetase; 30S ribosomal protein S12 methylthiotransferase 3499289..3500614 Escherichia coli O104:H4 str. 2009EL-2050 13689884 YP_006771058.1 CDS O3M_17150 NC_018650.1 3500661 3501989 R COG2199 FOG: GGDEF domain; diguanylate cyclase complement(3500661..3501989) Escherichia coli O104:H4 str. 2009EL-2050 13689885 YP_006771059.1 CDS O3M_17155 NC_018650.1 3501997 3504345 R COG2200 FOG: EAL domain; hypothetical protein complement(3501997..3504345) Escherichia coli O104:H4 str. 2009EL-2050 13689886 YP_006771060.1 CDS O3M_17160 NC_018650.1 3504523 3505434 R COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; glutathione ABC transporter permease GsiD complement(3504523..3505434) Escherichia coli O104:H4 str. 2009EL-2050 13689887 YP_006771061.1 CDS O3M_17165 NC_018650.1 3505437 3506357 R COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; glutathione ABC transporter permease GsiC complement(3505437..3506357) Escherichia coli O104:H4 str. 2009EL-2050 13689888 YP_006771062.1 CDS O3M_17170 NC_018650.1 3506375 3507913 R COG0747 ABC-type dipeptide transport system, periplasmic component; glutathione ABC transporter substrate-binding protein GsiB complement(3506375..3507913) Escherichia coli O104:H4 str. 2009EL-2050 13689889 YP_006771063.1 CDS O3M_17175 NC_018650.1 3507933 3509804 R COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; glutathione transporter ATP-binding protein complement(3507933..3509804) Escherichia coli O104:H4 str. 2009EL-2050 13689890 YP_006771064.1 CDS O3M_17180 NC_018650.1 3509791 3510756 R COG1446 Asparaginase; isoaspartyl peptidase complement(3509791..3510756) Escherichia coli O104:H4 str. 2009EL-2050 13689891 YP_006771065.1 CDS O3M_17185 NC_018650.1 3510960 3512195 D COG0303 Molybdopterin biosynthesis enzyme; molybdopterin biosynthesis protein MoeA 3510960..3512195 Escherichia coli O104:H4 str. 2009EL-2050 13689892 YP_006771066.1 CDS O3M_17190 NC_018650.1 3512195 3512944 D COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; molybdopterin biosynthesis protein MoeB 3512195..3512944 Escherichia coli O104:H4 str. 2009EL-2050 13689893 YP_006771067.1 CDS O3M_17195 NC_018650.1 3513032 3513694 R COG0176 Transaldolase; fructose-6-phosphate aldolase complement(3513032..3513694) Escherichia coli O104:H4 str. 2009EL-2050 13689894 YP_006771068.1 CDS O3M_17200 NC_018650.1 3513825 3514724 D COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate-lyase 3 activating protein 3513825..3514724 Escherichia coli O104:H4 str. 2009EL-2050 13689895 YP_006771069.1 CDS O3M_17205 NC_018650.1 3514730 3517162 D COG1882 Pyruvate-formate lyase; pyruvate formate lyase 3514730..3517162 Escherichia coli O104:H4 str. 2009EL-2050 13689896 YP_006771070.1 CDS O3M_17210 NC_018650.1 3517308 3518123 D COG0561 Predicted hydrolases of the HAD superfamily; hydrolase 3517308..3518123 Escherichia coli O104:H4 str. 2009EL-2050 13689897 YP_006771071.1 CDS O3M_17215 NC_018650.1 3518275 3519540 D hypothetical protein 3518275..3519540 Escherichia coli O104:H4 str. 2009EL-2050 13689898 YP_006771072.1 CDS O3M_17220 NC_018650.1 3519796 3520776 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(3519796..3520776) Escherichia coli O104:H4 str. 2009EL-2050 13689899 YP_006771073.1 CDS O3M_17225 NC_018650.1 3521055 3522647 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein complement(3521055..3522647) Escherichia coli O104:H4 str. 2009EL-2050 13689900 YP_006771074.1 CDS O3M_17230 NC_018650.1 3522866 3523786 D COG1376 Uncharacterized protein conserved in bacteria; L,D-transpeptidase 3522866..3523786 Escherichia coli O104:H4 str. 2009EL-2050 13689901 YP_006771075.1 CDS O3M_17235 NC_018650.1 3523845 3524963 R COG0471 Di- and tricarboxylate transporters; transporter complement(3523845..3524963) Escherichia coli O104:H4 str. 2009EL-2050 13689902 YP_006771076.1 CDS O3M_17240 NC_018650.1 3524960 3525427 R COG1321 Mn-dependent transcriptional regulator; manganese transport regulator MntR complement(3524960..3525427) Escherichia coli O104:H4 str. 2009EL-2050 13689903 YP_006771077.1 CDS O3M_17245 NC_018650.1 3526013 3527596 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; hydrolase, inner membrane 3526013..3527596 Escherichia coli O104:H4 str. 2009EL-2050 13689904 YP_006771078.1 CDS ompX NC_018650.1 3527645 3528160 R COG3637 Opacity protein and related surface antigens; outer membrane protein X complement(3527645..3528160) Escherichia coli O104:H4 str. 2009EL-2050 13689905 YP_006771079.1 CDS O3M_17255 NC_018650.1 3528513 3529400 D COG5006 Predicted permease, DMT superfamily; threonine and homoserine efflux system 3528513..3529400 Escherichia coli O104:H4 str. 2009EL-2050 13689906 YP_006771080.1 CDS O3M_17260 NC_018650.1 3529699 3530202 D COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); DNA starvation/stationary phase protection protein Dps 3529699..3530202 Escherichia coli O104:H4 str. 2009EL-2050 13689907 YP_006771081.1 CDS glnH NC_018650.1 3530606 3531352 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamine ABC transporter substrate-binding protein 3530606..3531352 Escherichia coli O104:H4 str. 2009EL-2050 13689908 YP_006771082.1 CDS glnP NC_018650.1 3531491 3532150 D COG0765 ABC-type amino acid transport system, permease component; glutamine ABC transporter permease 3531491..3532150 Escherichia coli O104:H4 str. 2009EL-2050 13689909 YP_006771083.1 CDS glnQ NC_018650.1 3532147 3532869 D COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein 3532147..3532869 Escherichia coli O104:H4 str. 2009EL-2050 13689910 YP_006771084.1 CDS O3M_17280 NC_018650.1 3532986 3535211 D COG0668 Small-conductance mechanosensitive channel; mechanosensitive channel protein 3532986..3535211 Escherichia coli O104:H4 str. 2009EL-2050 13690137 YP_006771085.1 CDS O3M_17285 NC_018650.1 3535208 3536134 R COG3129 Predicted SAM-dependent methyltransferase; 23S rRNA mA1618 methyltransferase complement(3535208..3536134) Escherichia coli O104:H4 str. 2009EL-2050 13690138 YP_006771086.1 CDS O3M_17290 NC_018650.1 3536266 3536670 D hypothetical protein 3536266..3536670 Escherichia coli O104:H4 str. 2009EL-2050 13690139 YP_006771087.1 CDS O3M_17295 NC_018650.1 3536935 3539217 D COG4774 Outer membrane receptor for monomeric catechols; catecholate siderophore receptor Fiu 3536935..3539217 Escherichia coli O104:H4 str. 2009EL-2050 13690140 YP_006771088.1 CDS O3M_17300 NC_018650.1 3539259 3539936 D COG3128 Uncharacterized iron-regulated protein; Fe(II)-dependent oxygenase superfamily protein 3539259..3539936 Escherichia coli O104:H4 str. 2009EL-2050 13690141 YP_006771089.1 CDS O3M_17305 NC_018650.1 3540010 3540276 D COG1734 DnaK suppressor protein; hypothetical protein 3540010..3540276 Escherichia coli O104:H4 str. 2009EL-2050 13690142 YP_006771090.1 CDS O3M_17310 NC_018650.1 3540541 3540801 D hypothetical protein 3540541..3540801 Escherichia coli O104:H4 str. 2009EL-2050 13690143 YP_006771091.1 CDS O3M_17315 NC_018650.1 3541030 3542115 R COG2055 Malate/L-lactate dehydrogenases; dehydrogenase complement(3541030..3542115) Escherichia coli O104:H4 str. 2009EL-2050 13690144 YP_006771092.1 CDS O3M_17320 NC_018650.1 3542256 3543218 R COG0547 Anthranilate phosphoribosyltransferase; glycosyl transferase family protein complement(3542256..3543218) Escherichia coli O104:H4 str. 2009EL-2050 13690145 YP_006771093.1 CDS dinG NC_018650.1 3543246 3545396 R COG1199 Rad3-related DNA helicases; ATP-dependent DNA helicase DinG complement(3543246..3545396) Escherichia coli O104:H4 str. 2009EL-2050 13690146 YP_006771094.1 CDS O3M_17330 NC_018650.1 3545516 3545998 D COG3236 Uncharacterized protein conserved in bacteria; hypothetical protein 3545516..3545998 Escherichia coli O104:H4 str. 2009EL-2050 13690147 YP_006771095.1 CDS O3M_17335 NC_018650.1 3546128 3546223 R hypothetical protein complement(3546128..3546223) Escherichia coli O104:H4 str. 2009EL-2050 13690148 YP_006771096.1 CDS O3M_17340 NC_018650.1 3546230 3547594 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlE complement(3546230..3547594) Escherichia coli O104:H4 str. 2009EL-2050 13690149 YP_006771097.1 CDS O3M_17345 NC_018650.1 3547823 3548494 D COG1309 Transcriptional regulator; DNA-binding transcriptional regulator 3547823..3548494 Escherichia coli O104:H4 str. 2009EL-2050 13690150 YP_006771098.1 CDS O3M_17350 NC_018650.1 3548497 3549492 D COG0845 Membrane-fusion protein; efflux pump membrane fusion protein 3548497..3549492 Escherichia coli O104:H4 str. 2009EL-2050 13690151 YP_006771099.1 CDS O3M_17355 NC_018650.1 3549485 3551221 D COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 3549485..3551221 Escherichia coli O104:H4 str. 2009EL-2050 13690152 YP_006771100.1 CDS O3M_17360 NC_018650.1 3551214 3552347 D COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 3551214..3552347 Escherichia coli O104:H4 str. 2009EL-2050 13690153 YP_006771101.1 CDS O3M_17365 NC_018650.1 3552358 3553464 D COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 3552358..3553464 Escherichia coli O104:H4 str. 2009EL-2050 13690154 YP_006771102.1 CDS O3M_17370 NC_018650.1 3553426 3553836 R COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; hypothetical protein complement(3553426..3553836) Escherichia coli O104:H4 str. 2009EL-2050 13690155 YP_006771103.1 CDS O3M_17375 NC_018650.1 3553969 3554730 D COG3568 Metal-dependent hydrolase; hypothetical protein 3553969..3554730 Escherichia coli O104:H4 str. 2009EL-2050 13690156 YP_006771104.1 CDS O3M_17380 NC_018650.1 3554727 3555968 D COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; cardiolipin synthase 2 3554727..3555968 Escherichia coli O104:H4 str. 2009EL-2050 13690157 YP_006771105.1 CDS O3M_17385 NC_018650.1 3555968 3556924 D COG0392 Predicted integral membrane protein; hypothetical protein 3555968..3556924 Escherichia coli O104:H4 str. 2009EL-2050 13690158 YP_006771106.1 CDS O3M_17390 NC_018650.1 3556960 3557673 R COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein complement(3556960..3557673) Escherichia coli O104:H4 str. 2009EL-2050 13690159 YP_006771107.1 CDS O3M_17395 NC_018650.1 3557743 3558447 R COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein complement(3557743..3558447) Escherichia coli O104:H4 str. 2009EL-2050 13690160 YP_006771108.1 CDS O3M_17400 NC_018650.1 3558592 3559296 R COG0670 Integral membrane protein, interacts with FtsH; inner membrane protein complement(3558592..3559296) Escherichia coli O104:H4 str. 2009EL-2050 13690161 YP_006771109.1 CDS moaE NC_018650.1 3559433 3559885 R COG0314 Molybdopterin converting factor, large subunit; molybdopterin guanine dinucleotide biosynthesis protein MoaE complement(3559433..3559885) Escherichia coli O104:H4 str. 2009EL-2050 13690162 YP_006771110.1 CDS moaD NC_018650.1 3559887 3560132 R COG1977 Molybdopterin converting factor, small subunit; molybdopterin synthase small subunit complement(3559887..3560132) Escherichia coli O104:H4 str. 2009EL-2050 13690163 YP_006771111.1 CDS moaC NC_018650.1 3560125 3560610 R COG0315 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein MoaC complement(3560125..3560610) Escherichia coli O104:H4 str. 2009EL-2050 13690164 YP_006771112.1 CDS O3M_17420 NC_018650.1 3560613 3561125 R COG0521 Molybdopterin biosynthesis enzymes; molybdenum cofactor biosynthesis protein B complement(3560613..3561125) Escherichia coli O104:H4 str. 2009EL-2050 13690165 YP_006771113.1 CDS moaA NC_018650.1 3561147 3562136 R COG2896 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein A complement(3561147..3562136) Escherichia coli O104:H4 str. 2009EL-2050 13690166 YP_006771114.1 CDS O3M_17430 NC_018650.1 3562135 3562290 D hypothetical protein 3562135..3562290 Escherichia coli O104:H4 str. 2009EL-2050 13690167 YP_006771115.1 CDS O3M_17435 NC_018650.1 3562533 3563441 D COG0391 Uncharacterized conserved protein; transferase with NAD(P)-binding Rossmann-fold domain 3562533..3563441 Escherichia coli O104:H4 str. 2009EL-2050 13690168 YP_006771116.1 CDS O3M_17440 NC_018650.1 3563633 3565654 R COG0556 Helicase subunit of the DNA excision repair complex; excinuclease ABC subunit B complement(3563633..3565654) Escherichia coli O104:H4 str. 2009EL-2050 13690169 YP_006771117.1 CDS bioD NC_018650.1 3566240 3566917 R COG0132 Dethiobiotin synthetase; dithiobiotin synthetase complement(3566240..3566917) Escherichia coli O104:H4 str. 2009EL-2050 13690170 YP_006771118.1 CDS O3M_17450 NC_018650.1 3566910 3567665 R COG0500 SAM-dependent methyltransferases; biotin biosynthesis protein BioC complement(3566910..3567665) Escherichia coli O104:H4 str. 2009EL-2050 13690171 YP_006771119.1 CDS O3M_17455 NC_018650.1 3567652 3568806 R COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase complement(3567652..3568806) Escherichia coli O104:H4 str. 2009EL-2050 13690172 YP_006771120.1 CDS O3M_17460 NC_018650.1 3568803 3569843 R COG0502 Biotin synthase and related enzymes; biotin synthase complement(3568803..3569843) Escherichia coli O104:H4 str. 2009EL-2050 13690173 YP_006771121.1 CDS O3M_17465 NC_018650.1 3569930 3571219 D COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 3569930..3571219 Escherichia coli O104:H4 str. 2009EL-2050 13690174 YP_006771122.1 CDS O3M_17470 NC_018650.1 3571278 3571754 D COG1881 Phospholipid-binding protein; kinase inhibitor protein 3571278..3571754 Escherichia coli O104:H4 str. 2009EL-2050 13690175 YP_006771123.1 CDS O3M_17475 NC_018650.1 3572500 3573831 D COG2199 FOG: GGDEF domain; hypothetical protein 3572500..3573831 Escherichia coli O104:H4 str. 2009EL-2050 13690176 YP_006771124.1 CDS O3M_17480 NC_018650.1 3573905 3574489 R Qin prophage; tail fiber chaperone complement(3573905..3574489) Escherichia coli O104:H4 str. 2009EL-2050 13690177 YP_006771125.1 CDS O3M_17485 NC_018650.1 3574489 3576198 R phage tail fiber protein complement(3574489..3576198) Escherichia coli O104:H4 str. 2009EL-2050 13690178 YP_006771126.1 CDS O3M_17490 NC_018650.1 3576176 3577066 D hypothetical protein 3576176..3577066 Escherichia coli O104:H4 str. 2009EL-2050 13690179 YP_006771127.1 CDS O3M_17495 NC_018650.1 3577454 3577627 D hypothetical protein 3577454..3577627 Escherichia coli O104:H4 str. 2009EL-2050 13690180 YP_006771128.1 CDS O3M_17500 NC_018650.1 3577628 3578227 R Lom-like outer membrane protein of phage origin complement(3577628..3578227) Escherichia coli O104:H4 str. 2009EL-2050 13690181 YP_006771129.1 CDS O3M_17505 NC_018650.1 3578298 3581795 R COG4733 Phage-related protein, tail component; Host specificity protein J of prophage complement(3578298..3581795) Escherichia coli O104:H4 str. 2009EL-2050 13690182 YP_006771130.1 CDS O3M_17510 NC_018650.1 3581856 3582527 R COG4723 Phage-related protein, tail component; Tail assembly protein I complement(3581856..3582527) Escherichia coli O104:H4 str. 2009EL-2050 13690183 YP_006771131.1 CDS O3M_17515 NC_018650.1 3582425 3583168 R COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; tail fiber component K of prophage complement(3582425..3583168) Escherichia coli O104:H4 str. 2009EL-2050 13690184 YP_006771132.1 CDS O3M_17520 NC_018650.1 3583174 3583872 R COG4672 Phage-related protein; minor tail protein L complement(3583174..3583872) Escherichia coli O104:H4 str. 2009EL-2050 13690185 YP_006771133.1 CDS O3M_17525 NC_018650.1 3583872 3584201 R COG4718 Phage-related protein; minor tail protein M complement(3583872..3584201) Escherichia coli O104:H4 str. 2009EL-2050 13690186 YP_006771134.1 CDS O3M_17530 NC_018650.1 3584198 3586759 R minor tail protein H complement(3584198..3586759) Escherichia coli O104:H4 str. 2009EL-2050 13690187 YP_006771135.1 CDS O3M_17535 NC_018650.1 3586752 3587186 R minor tail protein complement(3586752..3587186) Escherichia coli O104:H4 str. 2009EL-2050 13690188 YP_006771136.1 CDS O3M_17540 NC_018650.1 3587168 3587590 R minor tail protein G complement(3587168..3587590) Escherichia coli O104:H4 str. 2009EL-2050 13690189 YP_006771137.1 CDS O3M_17545 NC_018650.1 3587606 3588346 R COG5492 Bacterial surface proteins containing Ig-like domains; major tail protein V complement(3587606..3588346) Escherichia coli O104:H4 str. 2009EL-2050 13690190 YP_006771138.1 CDS O3M_17550 NC_018650.1 3588354 3588749 R COG0477 Permeases of the major facilitator superfamily; minor tail protein U complement(3588354..3588749) Escherichia coli O104:H4 str. 2009EL-2050 13690191 YP_006771139.1 CDS O3M_17555 NC_018650.1 3588746 3589324 R minor tail protein Z (GpZ) complement(3588746..3589324) Escherichia coli O104:H4 str. 2009EL-2050 13690192 YP_006771140.1 CDS O3M_17560 NC_018650.1 3589336 3589689 R Tail attachment protein (Minor capsid protein FII) from bacteriophage origin complement(3589336..3589689) Escherichia coli O104:H4 str. 2009EL-2050 13690193 YP_006771141.1 CDS O3M_17565 NC_018650.1 3589701 3590096 R phage DNA packaging protein complement(3589701..3590096) Escherichia coli O104:H4 str. 2009EL-2050 13690194 YP_006771142.1 CDS O3M_17570 NC_018650.1 3590138 3591163 R major head coat protein from bacteriophage origin complement(3590138..3591163) Escherichia coli O104:H4 str. 2009EL-2050 13690195 YP_006771143.1 CDS O3M_17575 NC_018650.1 3591219 3591551 R Head decoration protein from bacteriophage origin complement(3591219..3591551) Escherichia coli O104:H4 str. 2009EL-2050 13690196 YP_006771144.1 CDS O3M_17580 NC_018650.1 3591561 3592880 R COG0616 Periplasmic serine proteases (ClpP class); minor capsid protein C from bacteriophage origin complement(3591561..3592880) Escherichia coli O104:H4 str. 2009EL-2050 13690197 YP_006771145.1 CDS O3M_17585 NC_018650.1 3592861 3594462 R COG5511 Bacteriophage capsid protein; phage portal protein, lambda family complement(3592861..3594462) Escherichia coli O104:H4 str. 2009EL-2050 13690198 YP_006771146.1 CDS O3M_17590 NC_018650.1 3594459 3594665 R Lambda prophage-derived head-to-tail joining protein W complement(3594459..3594665) Escherichia coli O104:H4 str. 2009EL-2050 13690199 YP_006771147.1 CDS O3M_17595 NC_018650.1 3594662 3594880 R bacteriophage tail assembly protein complement(3594662..3594880) Escherichia coli O104:H4 str. 2009EL-2050 13690200 YP_006771148.1 CDS O3M_17600 NC_018650.1 3594925 3596586 R COG5525 Bacteriophage tail assembly protein; Terminase large subunit from bacteriophage origin complement(3594925..3596586) Escherichia coli O104:H4 str. 2009EL-2050 13690201 YP_006771149.1 CDS O3M_17605 NC_018650.1 3596561 3597106 R COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; terminase small subunit complement(3596561..3597106) Escherichia coli O104:H4 str. 2009EL-2050 13690202 YP_006771150.1 CDS O3M_17610 NC_018650.1 3597495 3597728 D Qin prophage 3597495..3597728 Escherichia coli O104:H4 str. 2009EL-2050 13690203 YP_006771151.1 CDS O3M_17615 NC_018650.1 3597785 3598195 D COG5562 Phage envelope protein; phage protein 3597785..3598195 Escherichia coli O104:H4 str. 2009EL-2050 13690204 YP_006771152.1 CDS O3M_17620 NC_018650.1 3598545 3599066 R phage protein complement(3598545..3599066) Escherichia coli O104:H4 str. 2009EL-2050 13690205 YP_006771153.1 CDS O3M_17625 NC_018650.1 3599271 3599708 R bacteriophage lysis protein complement(3599271..3599708) Escherichia coli O104:H4 str. 2009EL-2050 13690206 YP_006771154.1 CDS O3M_17630 NC_018650.1 3599705 3600202 R DLP12 prophage; COG3772 Phage-related lysozyme (muraminidase); lysozyme complement(3599705..3600202) Escherichia coli O104:H4 str. 2009EL-2050 13690207 YP_006771155.1 CDS O3M_17635 NC_018650.1 3600202 3600417 R phage lysis protein complement(3600202..3600417) Escherichia coli O104:H4 str. 2009EL-2050 13690208 YP_006771156.1 CDS O3M_17640 NC_018650.1 3601006 3602088 D COG3203 Outer membrane protein (porin); outer membrane porin, DLP12 prophage 3601006..3602088 Escherichia coli O104:H4 str. 2009EL-2050 13690209 YP_006771157.1 CDS O3M_17645 NC_018650.1 3602277 3602660 R antitermination protein Q complement(3602277..3602660) Escherichia coli O104:H4 str. 2009EL-2050 13690210 YP_006771158.1 CDS O3M_17650 NC_018650.1 3602746 3602886 R hypothetical protein complement(3602746..3602886) Escherichia coli O104:H4 str. 2009EL-2050 13690211 YP_006771159.1 CDS O3M_17655 NC_018650.1 3602883 3603110 R COG4570 Holliday junction resolvase; endodeoxyribonuclease RUS complement(3602883..3603110) Escherichia coli O104:H4 str. 2009EL-2050 13690212 YP_006771160.1 CDS O3M_17660 NC_018650.1 3603241 3603531 R hypothetical protein complement(3603241..3603531) Escherichia coli O104:H4 str. 2009EL-2050 13690213 YP_006771161.1 CDS O3M_17665 NC_018650.1 3603524 3603694 R prophage protein NinE complement(3603524..3603694) Escherichia coli O104:H4 str. 2009EL-2050 13690214 YP_006771162.1 CDS O3M_17670 NC_018650.1 3603694 3604149 R hypothetical protein complement(3603694..3604149) Escherichia coli O104:H4 str. 2009EL-2050 13690215 YP_006771163.1 CDS O3M_17675 NC_018650.1 3604344 3604853 R hypothetical protein complement(3604344..3604853) Escherichia coli O104:H4 str. 2009EL-2050 13690216 YP_006771164.1 CDS O3M_17680 NC_018650.1 3605172 3605411 R antirepressor protein complement(3605172..3605411) Escherichia coli O104:H4 str. 2009EL-2050 13690217 YP_006771165.1 CDS O3M_17685 NC_018650.1 3605523 3606317 R COG1961 Site-specific recombinases, DNA invertase Pin homologs; phage recombinase complement(3605523..3606317) Escherichia coli O104:H4 str. 2009EL-2050 13690218 YP_006771166.1 CDS emrE NC_018650.1 3606274 3606516 R COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein complement(3606274..3606516) Escherichia coli O104:H4 str. 2009EL-2050 13690219 YP_006771167.1 CDS O3M_17695 NC_018650.1 3606563 3606865 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Ren protein from phage origin complement(3606563..3606865) Escherichia coli O104:H4 str. 2009EL-2050 13690220 YP_006771168.1 CDS O3M_17700 NC_018650.1 3606862 3607563 R replication protein P of bacteriophage complement(3606862..3607563) Escherichia coli O104:H4 str. 2009EL-2050 13690221 YP_006771169.1 CDS O3M_17705 NC_018650.1 3607560 3608489 R Replication protein O frm phage origin complement(3607560..3608489) Escherichia coli O104:H4 str. 2009EL-2050 13690222 YP_006771170.1 CDS O3M_17710 NC_018650.1 3608576 3609115 R coiled-coil; Regulatory protein CII (modular protein) from bacteriophage origin complement(3608576..3609115) Escherichia coli O104:H4 str. 2009EL-2050 13690223 YP_006771171.1 CDS O3M_17715 NC_018650.1 3609185 3609415 R phage regulatory protein Cro complement(3609185..3609415) Escherichia coli O104:H4 str. 2009EL-2050 13690224 YP_006771172.1 CDS O3M_17720 NC_018650.1 3609521 3610210 D COG2932 Predicted transcriptional regulator; phage repressor protein CI 3609521..3610210 Escherichia coli O104:H4 str. 2009EL-2050 13690225 YP_006771173.1 CDS O3M_17725 NC_018650.1 3610808 3611014 D prophage Kil protein 3610808..3611014 Escherichia coli O104:H4 str. 2009EL-2050 13690226 YP_006771174.1 CDS O3M_17730 NC_018650.1 3611090 3611386 D host-nuclease inhibitor protein Gam of bacteriophage 3611090..3611386 Escherichia coli O104:H4 str. 2009EL-2050 13690227 YP_006771175.1 CDS O3M_17735 NC_018650.1 3611392 3612177 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Bet protein 3611392..3612177 Escherichia coli O104:H4 str. 2009EL-2050 13690228 YP_006771176.1 CDS O3M_17740 NC_018650.1 3612174 3612854 D exonuclease from phage origin 3612174..3612854 Escherichia coli O104:H4 str. 2009EL-2050 13690229 YP_006771177.1 CDS O3M_17745 NC_018650.1 3612845 3613033 D hypothetical protein 3612845..3613033 Escherichia coli O104:H4 str. 2009EL-2050 13690230 YP_006771178.1 CDS O3M_17750 NC_018650.1 3613006 3613197 D phage protein 3613006..3613197 Escherichia coli O104:H4 str. 2009EL-2050 13690231 YP_006771179.1 CDS O3M_17755 NC_018650.1 3613194 3613277 D hypothetical protein 3613194..3613277 Escherichia coli O104:H4 str. 2009EL-2050 13690232 YP_006771180.1 CDS O3M_17760 NC_018650.1 3613208 3613489 D hypothetical protein 3613208..3613489 Escherichia coli O104:H4 str. 2009EL-2050 13690233 YP_006771181.1 CDS O3M_17765 NC_018650.1 3613588 3613809 D COG1734 DnaK suppressor protein; hypothetical protein 3613588..3613809 Escherichia coli O104:H4 str. 2009EL-2050 13690234 YP_006771182.1 CDS O3M_17770 NC_018650.1 3614020 3614550 R hypothetical protein complement(3614020..3614550) Escherichia coli O104:H4 str. 2009EL-2050 13690235 YP_006771183.1 CDS O3M_17775 NC_018650.1 3614865 3615032 D hypothetical protein 3614865..3615032 Escherichia coli O104:H4 str. 2009EL-2050 13690236 YP_006771184.1 CDS O3M_17780 NC_018650.1 3615072 3615290 D excisionase 3615072..3615290 Escherichia coli O104:H4 str. 2009EL-2050 13690237 YP_006771185.1 CDS O3M_17785 NC_018650.1 3615268 3616338 D COG0582 Integrase; Integrase from phage 3615268..3616338 Escherichia coli O104:H4 str. 2009EL-2050 13690238 YP_006771186.1 CDS O3M_17790 NC_018650.1 3616473 3617756 D COG4677 Pectin methylesterase; acyl-CoA thioesterase 3616473..3617756 Escherichia coli O104:H4 str. 2009EL-2050 13690239 YP_006771187.1 CDS O3M_17795 NC_018650.1 3617990 3620251 R COG1048 Aconitase A; hydratase complement(3617990..3620251) Escherichia coli O104:H4 str. 2009EL-2050 13690240 YP_006771188.1 CDS O3M_17800 NC_018650.1 3620434 3621867 R COG0471 Di- and tricarboxylate transporters; transporter complement(3620434..3621867) Escherichia coli O104:H4 str. 2009EL-2050 13690241 YP_006771189.1 CDS O3M_17805 NC_018650.1 3621943 3622995 R COG2828 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3621943..3622995) Escherichia coli O104:H4 str. 2009EL-2050 13690242 YP_006771190.1 CDS O3M_17810 NC_018650.1 3623179 3624132 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 3623179..3624132 Escherichia coli O104:H4 str. 2009EL-2050 13690243 YP_006771191.1 CDS O3M_17815 NC_018650.1 3624173 3625168 R COG2706 3-carboxymuconate cyclase; 6-phosphogluconolactonase complement(3624173..3625168) Escherichia coli O104:H4 str. 2009EL-2050 13690244 YP_006771192.1 CDS O3M_17820 NC_018650.1 3625323 3626141 D COG0561 Predicted hydrolases of the HAD superfamily; pyridoxal phosphate (PLP) phosphatase 3625323..3626141 Escherichia coli O104:H4 str. 2009EL-2050 13690245 YP_006771193.1 CDS modC NC_018650.1 3626142 3627200 R COG4148 ABC-type molybdate transport system, ATPase component; molybdate transporter ATP-binding protein complement(3626142..3627200) Escherichia coli O104:H4 str. 2009EL-2050 13690246 YP_006771194.1 CDS modB NC_018650.1 3627203 3627892 R COG4149 ABC-type molybdate transport system, permease component; molybdate ABC transporter permease complement(3627203..3627892) Escherichia coli O104:H4 str. 2009EL-2050 13690247 YP_006771195.1 CDS modA NC_018650.1 3627892 3628665 R COG0725 ABC-type molybdate transport system, periplasmic component; molybdate transporter periplasmic protein complement(3627892..3628665) Escherichia coli O104:H4 str. 2009EL-2050 13690248 YP_006771196.1 CDS O3M_17840 NC_018650.1 3628832 3628981 R hypothetical protein complement(3628832..3628981) Escherichia coli O104:H4 str. 2009EL-2050 13690249 YP_006771197.1 CDS O3M_17845 NC_018650.1 3629110 3629898 D COG2005 N-terminal domain of molybdenum-binding protein; DNA-binding transcriptional regulator ModE 3629110..3629898 Escherichia coli O104:H4 str. 2009EL-2050 13690250 YP_006771198.1 CDS O3M_17850 NC_018650.1 3629966 3631438 D COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; molybdenum transport ATP-binding protein ModF 3629966..3631438 Escherichia coli O104:H4 str. 2009EL-2050 13690251 YP_006771199.1 CDS O3M_17855 NC_018650.1 3631699 3632715 D COG1087 UDP-glucose 4-epimerase; UDP-galactose-4-epimerase 3631699..3632715 Escherichia coli O104:H4 str. 2009EL-2050 13690252 YP_006771200.1 CDS O3M_17860 NC_018650.1 3632725 3633771 D COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 3632725..3633771 Escherichia coli O104:H4 str. 2009EL-2050 13690253 YP_006771201.1 CDS O3M_17865 NC_018650.1 3633775 3634923 D COG0153 Galactokinase; galactokinase 3633775..3634923 Escherichia coli O104:H4 str. 2009EL-2050 13690254 YP_006771202.1 CDS galM NC_018650.1 3634917 3635957 D COG2017 Galactose mutarotase and related enzymes; galactose-1-epimerase 3634917..3635957 Escherichia coli O104:H4 str. 2009EL-2050 13690255 YP_006771203.1 CDS gpmA NC_018650.1 3636162 3636914 D COG0588 Phosphoglycerate mutase 1; phosphoglyceromutase 3636162..3636914 Escherichia coli O104:H4 str. 2009EL-2050 13690256 YP_006771204.1 CDS O3M_17880 NC_018650.1 3637072 3638124 R COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3637072..3638124) Escherichia coli O104:H4 str. 2009EL-2050 13690257 YP_006771205.1 CDS O3M_17885 NC_018650.1 3638440 3638820 D hypothetical protein 3638440..3638820 Escherichia coli O104:H4 str. 2009EL-2050 13690258 YP_006771206.1 CDS O3M_17890 NC_018650.1 3638934 3639875 D COG1230 Co/Zn/Cd efflux system component; zinc transporter ZitB 3638934..3639875 Escherichia coli O104:H4 str. 2009EL-2050 13690259 YP_006771207.1 CDS O3M_17895 NC_018650.1 3639872 3640591 R COG3201 Nicotinamide mononucleotide transporter; nicotinamide riboside transporter PnuC complement(3639872..3640591) Escherichia coli O104:H4 str. 2009EL-2050 13690260 YP_006771208.1 CDS O3M_17900 NC_018650.1 3640629 3641672 R COG0379 Quinolinate synthase; quinolinate synthetase complement(3640629..3641672) Escherichia coli O104:H4 str. 2009EL-2050 13690261 YP_006771209.1 CDS O3M_17905 NC_018650.1 3643141 3643932 R COG1729 Uncharacterized protein conserved in bacteria; tol-pal system protein YbgF complement(3643141..3643932) Escherichia coli O104:H4 str. 2009EL-2050 13690269 YP_006771210.1 CDS O3M_17910 NC_018650.1 3643942 3644463 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated outer membrane lipoprotein complement(3643942..3644463) Escherichia coli O104:H4 str. 2009EL-2050 13690270 YP_006771211.1 CDS tolB NC_018650.1 3644498 3645790 R COG0823 Periplasmic component of the Tol biopolymer transport system; translocation protein TolB complement(3644498..3645790) Escherichia coli O104:H4 str. 2009EL-2050 13690271 YP_006771212.1 CDS tolA NC_018650.1 3645923 3647188 R COG3064 Membrane protein involved in colicin uptake; cell envelope integrity inner membrane protein TolA complement(3645923..3647188) Escherichia coli O104:H4 str. 2009EL-2050 13690272 YP_006771213.1 CDS O3M_17925 NC_018650.1 3647253 3647681 R COG0848 Biopolymer transport protein; colicin uptake protein TolR complement(3647253..3647681) Escherichia coli O104:H4 str. 2009EL-2050 13690273 YP_006771214.1 CDS O3M_17930 NC_018650.1 3647685 3648377 R COG0811 Biopolymer transport proteins; colicin uptake protein TolQ complement(3647685..3648377) Escherichia coli O104:H4 str. 2009EL-2050 13690274 YP_006771215.1 CDS O3M_17935 NC_018650.1 3648374 3648778 R COG0824 Predicted thioesterase; acyl-CoA thioesterase YbgC complement(3648374..3648778) Escherichia coli O104:H4 str. 2009EL-2050 13690275 YP_006771216.1 CDS O3M_17940 NC_018650.1 3648928 3649221 R COG3790 Predicted membrane protein; hypothetical protein complement(3648928..3649221) Escherichia coli O104:H4 str. 2009EL-2050 13690276 YP_006771217.1 CDS O3M_17945 NC_018650.1 3649221 3649334 R COG4890 Predicted outer membrane lipoprotein; cyd operon protein YbgT complement(3649221..3649334) Escherichia coli O104:H4 str. 2009EL-2050 13690277 YP_006771218.1 CDS O3M_17950 NC_018650.1 3649349 3650488 R COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome d ubiquinol oxidase subunit 2 complement(3649349..3650488) Escherichia coli O104:H4 str. 2009EL-2050 13690278 YP_006771219.1 CDS O3M_17955 NC_018650.1 3650504 3652072 R COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome d terminal oxidase subunit 1 complement(3650504..3652072) Escherichia coli O104:H4 str. 2009EL-2050 13690279 YP_006771220.1 CDS O3M_17960 NC_018650.1 3652667 3652894 R hypothetical protein complement(3652667..3652894) Escherichia coli O104:H4 str. 2009EL-2050 13690280 YP_006771221.1 CDS O3M_17965 NC_018650.1 3652919 3655552 R COG0383 Alpha-mannosidase; alpha-mannosidase complement(3652919..3655552) Escherichia coli O104:H4 str. 2009EL-2050 13690281 YP_006771222.1 CDS O3M_17970 NC_018650.1 3655570 3657546 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC complement(3655570..3657546) Escherichia coli O104:H4 str. 2009EL-2050 13690282 YP_006771223.1 CDS O3M_17975 NC_018650.1 3657655 3658377 D COG2188 Transcriptional regulators; DNA-binding transcriptional repressor MngR 3657655..3658377 Escherichia coli O104:H4 str. 2009EL-2050 13690283 YP_006771224.1 CDS O3M_17980 NC_018650.1 3658481 3659350 R COG0074 Succinyl-CoA synthetase, alpha subunit; succinyl-CoA synthetase subunit alpha complement(3658481..3659350) Escherichia coli O104:H4 str. 2009EL-2050 13690284 YP_006771225.1 CDS sucC NC_018650.1 3659350 3660516 R COG0045 Succinyl-CoA synthetase, beta subunit; succinyl-CoA synthetase subunit beta complement(3659350..3660516) Escherichia coli O104:H4 str. 2009EL-2050 13690285 YP_006771226.1 CDS O3M_17990 NC_018650.1 3660610 3661827 R COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; dihydrolipoamide succinyltransferase complement(3660610..3661827) Escherichia coli O104:H4 str. 2009EL-2050 13690286 YP_006771227.1 CDS sucA NC_018650.1 3661842 3664643 R COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; 2-oxoglutarate dehydrogenase E1 component complement(3661842..3664643) Escherichia coli O104:H4 str. 2009EL-2050 13690287 YP_006771228.1 CDS sdhB NC_018650.1 3664844 3665560 R COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; succinate dehydrogenase iron-sulfur subunit complement(3664844..3665560) Escherichia coli O104:H4 str. 2009EL-2050 13690288 YP_006771229.1 CDS sdhA NC_018650.1 3665576 3667342 R COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; succinate dehydrogenase flavoprotein subunit complement(3665576..3667342) Escherichia coli O104:H4 str. 2009EL-2050 13690289 YP_006771230.1 CDS sdhD NC_018650.1 3667342 3667689 R COG2142 Succinate dehydrogenase, hydrophobic anchor subunit; succinate dehydrogenase cytochrome b556 small membrane subunit complement(3667342..3667689) Escherichia coli O104:H4 str. 2009EL-2050 13690290 YP_006771231.1 CDS sdhC NC_018650.1 3667683 3668072 R COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; succinate dehydrogenase cytochrome b556 large membrane subunit complement(3667683..3668072) Escherichia coli O104:H4 str. 2009EL-2050 13690291 YP_006771232.1 CDS O3M_18020 NC_018650.1 3668608 3668793 R hypothetical protein complement(3668608..3668793) Escherichia coli O104:H4 str. 2009EL-2050 13690292 YP_006771233.1 CDS gltA NC_018650.1 3668781 3670064 D COG0372 Citrate synthase; type II citrate synthase 3668781..3670064 Escherichia coli O104:H4 str. 2009EL-2050 13690293 YP_006771234.1 CDS O3M_18030 NC_018650.1 3670454 3671020 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like protein 3670454..3671020 Escherichia coli O104:H4 str. 2009EL-2050 13690294 YP_006771235.1 CDS O3M_18035 NC_018650.1 3671080 3671328 D COG3188 P pilus assembly protein, porin PapC; fimbrial biogenesis outer membrane usher protein 3671080..3671328 Escherichia coli O104:H4 str. 2009EL-2050 13690295 YP_006771236.1 CDS O3M_18040 NC_018650.1 3671357 3671632 D COG3677 Transposase and inactivated derivatives; InsA 3671357..3671632 Escherichia coli O104:H4 str. 2009EL-2050 13690296 YP_006771237.1 CDS O3M_18045 NC_018650.1 3671551 3672054 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 3671551..3672054 Escherichia coli O104:H4 str. 2009EL-2050 13690297 YP_006771238.1 CDS O3M_18050 NC_018650.1 3672089 3672739 D hypothetical protein 3672089..3672739 Escherichia coli O104:H4 str. 2009EL-2050 13690298 YP_006771239.1 CDS O3M_18055 NC_018650.1 3672891 3673937 D COG3180 Putative ammonia monooxygenase; transporter 3672891..3673937 Escherichia coli O104:H4 str. 2009EL-2050 13690299 YP_006771240.1 CDS O3M_18060 NC_018650.1 3673934 3674725 R COG0266 Formamidopyrimidine-DNA glycosylase; endonuclease VIII complement(3673934..3674725) Escherichia coli O104:H4 str. 2009EL-2050 13690300 YP_006771241.1 CDS O3M_18065 NC_018650.1 3674761 3675495 R COG1540 Uncharacterized proteins, homologs of lactam utilization protein B; LamB/YcsF family protein complement(3674761..3675495) Escherichia coli O104:H4 str. 2009EL-2050 13690301 YP_006771242.1 CDS O3M_18070 NC_018650.1 3675485 3676417 R COG1984 Allophanate hydrolase subunit 2; hydrolase subunit complement(3675485..3676417) Escherichia coli O104:H4 str. 2009EL-2050 13690302 YP_006771243.1 CDS O3M_18075 NC_018650.1 3676411 3677067 R COG2049 Allophanate hydrolase subunit 1; carboxylase complement(3676411..3677067) Escherichia coli O104:H4 str. 2009EL-2050 13690303 YP_006771244.1 CDS O3M_18080 NC_018650.1 3677090 3677833 R COG0327 Uncharacterized conserved protein; metal-binding protein complement(3677090..3677833) Escherichia coli O104:H4 str. 2009EL-2050 13690304 YP_006771245.1 CDS O3M_18085 NC_018650.1 3678104 3679585 D COG3104 Dipeptide/tripeptide permease; dipeptide/tripeptide permease D 3678104..3679585 Escherichia coli O104:H4 str. 2009EL-2050 13690305 YP_006771246.1 CDS O3M_18090 NC_018650.1 3679627 3681045 R COG0415 Deoxyribodipyrimidine photolyase; deoxyribodipyrimidine photolyase complement(3679627..3681045) Escherichia coli O104:H4 str. 2009EL-2050 13690306 YP_006771247.1 CDS O3M_18095 NC_018650.1 3681042 3681551 R COG3272 Uncharacterized conserved protein; hypothetical protein complement(3681042..3681551) Escherichia coli O104:H4 str. 2009EL-2050 13690307 YP_006771248.1 CDS O3M_18100 NC_018650.1 3681699 3682385 R COG5433 Transposase; hypothetical protein complement(3681699..3682385) Escherichia coli O104:H4 str. 2009EL-2050 13690308 YP_006771249.1 CDS O3M_18105 NC_018650.1 3682586 3682840 R COG5433 Transposase; transposase complement(3682586..3682840) Escherichia coli O104:H4 str. 2009EL-2050 13690309 YP_006771250.1 CDS O3M_18110 NC_018650.1 3683066 3683635 R hypothetical protein complement(3683066..3683635) Escherichia coli O104:H4 str. 2009EL-2050 13690310 YP_006771251.1 CDS O3M_18115 NC_018650.1 3683632 3685065 R COG3209 Rhs family protein; RhsC core protein complement(3683632..3685065) Escherichia coli O104:H4 str. 2009EL-2050 13690311 YP_006771252.1 CDS O3M_18120 NC_018650.1 3685183 3685509 R hypothetical protein complement(3685183..3685509) Escherichia coli O104:H4 str. 2009EL-2050 13690312 YP_006771253.1 CDS O3M_18125 NC_018650.1 3685509 3689702 R COG3209 Rhs family protein; rhsC element core protein RshC complement(3685509..3689702) Escherichia coli O104:H4 str. 2009EL-2050 13690313 YP_006771254.1 CDS O3M_18130 NC_018650.1 3689945 3690151 R hypothetical protein complement(3689945..3690151) Escherichia coli O104:H4 str. 2009EL-2050 13690314 YP_006771255.1 CDS O3M_18135 NC_018650.1 3690464 3690553 D potassium ion accessory transporter subunit 3690464..3690553 Escherichia coli O104:H4 str. 2009EL-2050 13690315 YP_006771256.1 CDS O3M_18140 NC_018650.1 3690553 3692226 D COG2060 K+-transporting ATPase, A chain; potassium-transporting ATPase subunit A 3690553..3692226 Escherichia coli O104:H4 str. 2009EL-2050 13690316 YP_006771257.1 CDS O3M_18145 NC_018650.1 3692249 3694297 D COG2216 High-affinity K+ transport system, ATPase chain B; potassium-transporting ATPase subunit B 3692249..3694297 Escherichia coli O104:H4 str. 2009EL-2050 13690317 YP_006771258.1 CDS O3M_18150 NC_018650.1 3694306 3694878 D COG2156 K+-transporting ATPase, c chain; potassium-transporting ATPase subunit C 3694306..3694878 Escherichia coli O104:H4 str. 2009EL-2050 13690318 YP_006771259.1 CDS O3M_18155 NC_018650.1 3694871 3697555 D COG2205 Osmosensitive K+ channel histidine kinase; sensor protein KdpD 3694871..3697555 Escherichia coli O104:H4 str. 2009EL-2050 13690319 YP_006771260.1 CDS O3M_18160 NC_018650.1 3697552 3698229 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator KdpE 3697552..3698229 Escherichia coli O104:H4 str. 2009EL-2050 13690320 YP_006771261.1 CDS O3M_18165 NC_018650.1 3698919 3701117 D COG1982 Arginine/lysine/ornithine decarboxylases; ornithine decarboxylase 3698919..3701117 Escherichia coli O104:H4 str. 2009EL-2050 13690321 YP_006771262.1 CDS potE NC_018650.1 3701114 3702433 D COG0531 Amino acid transporters; putrescine transporter 3701114..3702433 Escherichia coli O104:H4 str. 2009EL-2050 13690322 YP_006771263.1 CDS O3M_18175 NC_018650.1 3702489 3704129 R COG0033 Phosphoglucomutase; phosphoglucomutase complement(3702489..3704129) Escherichia coli O104:H4 str. 2009EL-2050 13690323 YP_006771264.1 CDS O3M_18180 NC_018650.1 3704155 3704700 R COG3057 Negative regulator of replication initiationR; replication initiation regulator SeqA complement(3704155..3704700) Escherichia coli O104:H4 str. 2009EL-2050 13690324 YP_006771265.1 CDS O3M_18185 NC_018650.1 3704885 3705649 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); acyl-CoA esterase 3704885..3705649 Escherichia coli O104:H4 str. 2009EL-2050 13690325 YP_006771266.1 CDS O3M_18190 NC_018650.1 3705789 3706082 D LexA regulated protein 3705789..3706082 Escherichia coli O104:H4 str. 2009EL-2050 13690326 YP_006771267.1 CDS O3M_18195 NC_018650.1 3706222 3706752 D COG0716 Flavodoxins; flavodoxin FldA 3706222..3706752 Escherichia coli O104:H4 str. 2009EL-2050 13690327 YP_006771268.1 CDS O3M_18200 NC_018650.1 3706962 3707048 D ryhB-regulated fur leader peptide 3706962..3707048 Escherichia coli O104:H4 str. 2009EL-2050 13690328 YP_006771269.1 CDS fur NC_018650.1 3707041 3707487 D COG0735 Fe2+/Zn2+ uptake regulation proteins; ferric uptake regulator 3707041..3707487 Escherichia coli O104:H4 str. 2009EL-2050 13690329 YP_006771270.1 CDS O3M_18210 NC_018650.1 3707571 3707897 R COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein complement(3707571..3707897) Escherichia coli O104:H4 str. 2009EL-2050 13690330 YP_006771271.1 CDS O3M_18215 NC_018650.1 3707947 3709353 R outer membrane porin complement(3707947..3709353) Escherichia coli O104:H4 str. 2009EL-2050 13690331 YP_006771272.1 CDS O3M_18220 NC_018650.1 3709799 3711463 R COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutaminyl-tRNA synthetase complement(3709799..3711463) Escherichia coli O104:H4 str. 2009EL-2050 13690332 YP_006771273.1 CDS O3M_18225 NC_018650.1 3711666 3713612 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system N-acetyl glucosamine specific transporter subunit IIABC complement(3711666..3713612) Escherichia coli O104:H4 str. 2009EL-2050 13690333 YP_006771274.1 CDS nagB NC_018650.1 3713945 3714745 D COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; glucosamine-6-phosphate deaminase 3713945..3714745 Escherichia coli O104:H4 str. 2009EL-2050 13690334 YP_006771275.1 CDS nagA NC_018650.1 3714805 3715953 D COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 3714805..3715953 Escherichia coli O104:H4 str. 2009EL-2050 13690335 YP_006771276.1 CDS O3M_18240 NC_018650.1 3715962 3717182 D COG1940 Transcriptional regulator/sugar kinase; N-acetylglucosamine repressor 3715962..3717182 Escherichia coli O104:H4 str. 2009EL-2050 13690336 YP_006771277.1 CDS O3M_18245 NC_018650.1 3717230 3717982 D COG0647 Predicted sugar phosphatases of the HAD superfamily; UMP phosphatase 3717230..3717982 Escherichia coli O104:H4 str. 2009EL-2050 13690337 YP_006771278.1 CDS asnB NC_018650.1 3718239 3719903 D COG0367 Asparagine synthase (glutamine-hydrolyzing); asparagine synthetase B 3718239..3719903 Escherichia coli O104:H4 str. 2009EL-2050 13690338 YP_006771279.1 CDS ubiF NC_018650.1 3721141 3722316 R COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase complement(3721141..3722316) Escherichia coli O104:H4 str. 2009EL-2050 13690346 YP_006771280.1 CDS O3M_18260 NC_018650.1 3722462 3723886 D COG0621 2-methylthioadenine synthetase; (dimethylallyl)adenosine tRNA methylthiotransferase 3722462..3723886 Escherichia coli O104:H4 str. 2009EL-2050 13690347 YP_006771281.1 CDS O3M_18265 NC_018650.1 3724000 3725079 D COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; PhoH family protein 3724000..3725079 Escherichia coli O104:H4 str. 2009EL-2050 13690348 YP_006771282.1 CDS O3M_18270 NC_018650.1 3725076 3725543 D COG0319 Predicted metal-dependent hydrolase; metal-binding heat shock protein 3725076..3725543 Escherichia coli O104:H4 str. 2009EL-2050 13690349 YP_006771283.1 CDS O3M_18275 NC_018650.1 3725633 3726511 D COG4535 Putative Mg2+ and Co2+ transporter CorC; magnesium/cobalt efflux protein CorC 3725633..3726511 Escherichia coli O104:H4 str. 2009EL-2050 13690350 YP_006771284.1 CDS lnt NC_018650.1 3726536 3728074 D COG0815 Apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 3726536..3728074 Escherichia coli O104:H4 str. 2009EL-2050 13690351 YP_006771285.1 CDS O3M_18295 NC_018650.1 3730483 3731391 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamate and aspartate transporter subunit 3730483..3731391 Escherichia coli O104:H4 str. 2009EL-2050 13690352 YP_006771286.1 CDS O3M_18300 NC_018650.1 3731561 3732301 D COG0765 ABC-type amino acid transport system, permease component; glutamate/aspartate transport system permease GltJ 3731561..3732301 Escherichia coli O104:H4 str. 2009EL-2050 13690353 YP_006771287.1 CDS O3M_18305 NC_018650.1 3732301 3732975 D COG0765 ABC-type amino acid transport system, permease component; glutamate/aspartate transport system permease GltK 3732301..3732975 Escherichia coli O104:H4 str. 2009EL-2050 13690354 YP_006771288.1 CDS O3M_18310 NC_018650.1 3732975 3733700 D COG1126 ABC-type polar amino acid transport system, ATPase component; glutamate/aspartate transport ATP-binding protein gltL 3732975..3733700 Escherichia coli O104:H4 str. 2009EL-2050 13690355 YP_006771289.1 CDS rihA NC_018650.1 3733818 3734753 D COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase 1 3733818..3734753 Escherichia coli O104:H4 str. 2009EL-2050 13690356 YP_006771290.1 CDS O3M_18320 NC_018650.1 3734837 3736507 D COG0443 Molecular chaperone; molecular chaperone DnaK 3734837..3736507 Escherichia coli O104:H4 str. 2009EL-2050 13690357 YP_006771291.1 CDS O3M_18325 NC_018650.1 3736567 3738018 R Hsc56 co-chaperone of HscC complement(3736567..3738018) Escherichia coli O104:H4 str. 2009EL-2050 13690358 YP_006771292.1 CDS O3M_18330 NC_018650.1 3738015 3738722 R hypothetical protein complement(3738015..3738722) Escherichia coli O104:H4 str. 2009EL-2050 13690359 YP_006771293.1 CDS O3M_18335 NC_018650.1 3738823 3739377 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 3738823..3739377 Escherichia coli O104:H4 str. 2009EL-2050 13690360 YP_006771294.1 CDS O3M_18340 NC_018650.1 3739387 3740814 R COG2214 DnaJ-class molecular chaperone; DnaJ-class chaperone complement(3739387..3740814) Escherichia coli O104:H4 str. 2009EL-2050 13690361 YP_006771295.1 CDS O3M_18345 NC_018650.1 3740811 3741518 R hypothetical protein complement(3740811..3741518) Escherichia coli O104:H4 str. 2009EL-2050 13690362 YP_006771296.1 CDS O3M_18350 NC_018650.1 3741682 3742659 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 3741682..3742659 Escherichia coli O104:H4 str. 2009EL-2050 13690363 YP_006771297.1 CDS O3M_18355 NC_018650.1 3742729 3743211 R COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein complement(3742729..3743211) Escherichia coli O104:H4 str. 2009EL-2050 13690364 YP_006771298.1 CDS leuS NC_018650.1 3743446 3746028 D COG0495 Leucyl-tRNA synthetase; leucyl-tRNA synthetase 3743446..3746028 Escherichia coli O104:H4 str. 2009EL-2050 13690365 YP_006771299.1 CDS O3M_18365 NC_018650.1 3746043 3746624 D COG2980 Rare lipoprotein B; LPS-assembly lipoprotein RlpB 3746043..3746624 Escherichia coli O104:H4 str. 2009EL-2050 13690366 YP_006771300.1 CDS holA NC_018650.1 3746624 3747655 D COG1466 DNA polymerase III, delta subunit; DNA polymerase III subunit delta 3746624..3747655 Escherichia coli O104:H4 str. 2009EL-2050 13690367 YP_006771301.1 CDS nadD NC_018650.1 3747657 3748298 D COG1057 Nicotinic acid mononucleotide adenylyltransferase; nicotinic acid mononucleotide adenylyltransferase 3747657..3748298 Escherichia coli O104:H4 str. 2009EL-2050 13690368 YP_006771302.1 CDS O3M_18380 NC_018650.1 3748322 3748933 D COG0406 Fructose-2,6-bisphosphatase; alpha-ribazole phosphatase 3748322..3748933 Escherichia coli O104:H4 str. 2009EL-2050 13690369 YP_006771303.1 CDS O3M_18385 NC_018650.1 3749193 3749510 D COG0799 Uncharacterized homolog of plant Iojap protein; ribosome-associated protein 3749193..3749510 Escherichia coli O104:H4 str. 2009EL-2050 13690370 YP_006771304.1 CDS O3M_18390 NC_018650.1 3749514 3749981 D COG1576 Uncharacterized conserved protein; rRNA large subunit methyltransferase 3749514..3749981 Escherichia coli O104:H4 str. 2009EL-2050 13690371 YP_006771305.1 CDS O3M_18395 NC_018650.1 3750012 3751913 D COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 2 3750012..3751913 Escherichia coli O104:H4 str. 2009EL-2050 13690372 YP_006771306.1 CDS O3M_18400 NC_018650.1 3751916 3753028 D COG0772 Bacterial cell division membrane protein; cell wall shape-determining protein 3751916..3753028 Escherichia coli O104:H4 str. 2009EL-2050 13690373 YP_006771307.1 CDS O3M_18405 NC_018650.1 3753039 3754127 D COG0797 Lipoproteins; rare lipoprotein A 3753039..3754127 Escherichia coli O104:H4 str. 2009EL-2050 13690374 YP_006771308.1 CDS O3M_18410 NC_018650.1 3754266 3755477 D COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 3754266..3755477 Escherichia coli O104:H4 str. 2009EL-2050 13690375 YP_006771309.1 CDS O3M_18415 NC_018650.1 3755588 3755851 D COG2921 Uncharacterized conserved protein; hypothetical protein 3755588..3755851 Escherichia coli O104:H4 str. 2009EL-2050 13690376 YP_006771310.1 CDS O3M_18420 NC_018650.1 3755952 3756593 D COG0321 Lipoate-protein ligase B; lipoate-protein ligase B 3755952..3756593 Escherichia coli O104:H4 str. 2009EL-2050 13690377 YP_006771311.1 CDS O3M_18425 NC_018650.1 3756645 3756794 R COG0474 Cation transport ATPase; hypothetical protein complement(3756645..3756794) Escherichia coli O104:H4 str. 2009EL-2050 13690378 YP_006771312.1 CDS O3M_18430 NC_018650.1 3756852 3757805 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 3756852..3757805 Escherichia coli O104:H4 str. 2009EL-2050 13690379 YP_006771313.1 CDS O3M_18435 NC_018650.1 3758014 3758979 D COG0320 Lipoate synthase; lipoyl synthase 3758014..3758979 Escherichia coli O104:H4 str. 2009EL-2050 13690380 YP_006771314.1 CDS tatE NC_018650.1 3759080 3759283 R COG1826 Sec-independent protein secretion pathway components; twin arginine translocase protein E complement(3759080..3759283) Escherichia coli O104:H4 str. 2009EL-2050 13690381 YP_006771315.1 CDS O3M_18445 NC_018650.1 3759412 3760200 R COG0388 Predicted amidohydrolase; hypothetical protein complement(3759412..3760200) Escherichia coli O104:H4 str. 2009EL-2050 13690382 YP_006771316.1 CDS O3M_18450 NC_018650.1 3760293 3760676 D COG0239 Integral membrane protein possibly involved in chromosome condensation; chromosome condensation membrane protein 3760293..3760676 Escherichia coli O104:H4 str. 2009EL-2050 13690383 YP_006771317.1 CDS cspE NC_018650.1 3760730 3760939 R COG1278 Cold shock proteins; cold shock protein CspE complement(3760730..3760939) Escherichia coli O104:H4 str. 2009EL-2050 13690384 YP_006771318.1 CDS pagP NC_018650.1 3761114 3761674 R phospholipid:lipid A palmitoyltransferase complement(3761114..3761674) Escherichia coli O104:H4 str. 2009EL-2050 13690385 YP_006771319.1 CDS dcuC NC_018650.1 3762263 3763648 D COG3069 C4-dicarboxylate transporter; C4-dicarboxylate transporter DcuC 3762263..3763648 Escherichia coli O104:H4 str. 2009EL-2050 13690386 YP_006771320.1 CDS dpiA NC_018650.1 3763689 3764369 R COG4565 Response regulator of citrate/malate metabolism; two-component response regulator DpiA complement(3763689..3764369) Escherichia coli O104:H4 str. 2009EL-2050 13690387 YP_006771321.1 CDS dpiB NC_018650.1 3764338 3765996 R COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; sensor histidine kinase DpiB complement(3764338..3765996) Escherichia coli O104:H4 str. 2009EL-2050 13690388 YP_006771322.1 CDS O3M_18480 NC_018650.1 3766376 3767434 D COG3053 Citrate lyase synthetase; citrate lyase synthetase 3766376..3767434 Escherichia coli O104:H4 str. 2009EL-2050 13690389 YP_006771323.1 CDS O3M_18485 NC_018650.1 3767449 3767745 D COG3052 Citrate lyase, gamma subunit; citrate lyase subunit gamma 3767449..3767745 Escherichia coli O104:H4 str. 2009EL-2050 13690390 YP_006771324.1 CDS O3M_18490 NC_018650.1 3767742 3768650 D COG2301 Citrate lyase beta subunit; citrate lyase subunit beta 3767742..3768650 Escherichia coli O104:H4 str. 2009EL-2050 13690391 YP_006771325.1 CDS O3M_18495 NC_018650.1 3768661 3770193 D COG3051 Citrate lyase, alpha subunit; citrate lyase subunit alpha 3768661..3770193 Escherichia coli O104:H4 str. 2009EL-2050 13690392 YP_006771326.1 CDS citX NC_018650.1 3770197 3770748 D COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase); 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 3770197..3770748 Escherichia coli O104:H4 str. 2009EL-2050 13690393 YP_006771327.1 CDS citG NC_018650.1 3770723 3771601 D COG1767 Triphosphoribosyl-dephospho-CoA synthetase; triphosphoribosyl-dephospho-CoA synthase 3770723..3771601 Escherichia coli O104:H4 str. 2009EL-2050 13690394 YP_006771328.1 CDS O3M_18510 NC_018650.1 3771652 3773115 D COG0471 Di- and tricarboxylate transporters; citrate/succinate antiporter CitT 3771652..3773115 Escherichia coli O104:H4 str. 2009EL-2050 13690395 YP_006771329.1 CDS O3M_18515 NC_018650.1 3773229 3774035 D COG3719 Ribonuclease I; ribonuclease I 3773229..3774035 Escherichia coli O104:H4 str. 2009EL-2050 13690396 YP_006771330.1 CDS O3M_18520 NC_018650.1 3774265 3774675 D COG0782 Transcription elongation factor; nucleoside diphosphate kinase regulator 3774265..3774675 Escherichia coli O104:H4 str. 2009EL-2050 13690397 YP_006771331.1 CDS O3M_18525 NC_018650.1 3774906 3776144 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase zinc-binding dehydrogenase family protein complement(3774906..3776144) Escherichia coli O104:H4 str. 2009EL-2050 13690398 YP_006771332.1 CDS O3M_18530 NC_018650.1 3776365 3776793 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspG 3776365..3776793 Escherichia coli O104:H4 str. 2009EL-2050 13690399 YP_006771333.1 CDS O3M_18535 NC_018650.1 3776914 3778479 R COG3634 Alkyl hydroperoxide reductase, large subunit; alkyl hydroperoxide reductase subunit F complement(3776914..3778479) Escherichia coli O104:H4 str. 2009EL-2050 13690400 YP_006771334.1 CDS O3M_18540 NC_018650.1 3778608 3779171 R COG0450 Peroxiredoxin; alkyl hydroperoxide reductase subunit C complement(3778608..3779171) Escherichia coli O104:H4 str. 2009EL-2050 13690401 YP_006771335.1 CDS dsbG NC_018650.1 3779543 3780289 D COG1651 Protein-disulfide isomerase; disulfide isomerase/thiol-disulfide oxidase 3779543..3780289 Escherichia coli O104:H4 str. 2009EL-2050 13690402 YP_006771336.1 CDS O3M_18550 NC_018650.1 3780499 3781401 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 3780499..3781401 Escherichia coli O104:H4 str. 2009EL-2050 13690403 YP_006771337.1 CDS O3M_18555 NC_018650.1 3781548 3782768 D COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase; phosphoadenosine phosphosulfate reductase family protein 3781548..3782768 Escherichia coli O104:H4 str. 2009EL-2050 13690404 YP_006771338.1 CDS O3M_18560 NC_018650.1 3782753 3783370 D COG1475 Predicted transcriptional regulators; Immunoglobulin-binding regulator family protein 3782753..3783370 Escherichia coli O104:H4 str. 2009EL-2050 13690405 YP_006771339.1 CDS O3M_18565 NC_018650.1 3783371 3784531 R COG0436 Aspartate/tyrosine/aromatic aminotransferase; methionine aminotransferase complement(3783371..3784531) Escherichia coli O104:H4 str. 2009EL-2050 13690406 YP_006771340.1 CDS O3M_18570 NC_018650.1 3784640 3785728 D COG0371 Glycerol dehydrogenase and related enzymes; oxidoreductase 3784640..3785728 Escherichia coli O104:H4 str. 2009EL-2050 13690407 YP_006771341.1 CDS O3M_18575 NC_018650.1 3785738 3785935 R COG2879 Uncharacterized small protein; hypothetical protein complement(3785738..3785935) Escherichia coli O104:H4 str. 2009EL-2050 13690408 YP_006771342.1 CDS O3M_18580 NC_018650.1 3786117 3788222 R COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein A complement(3786117..3788222) Escherichia coli O104:H4 str. 2009EL-2050 13690409 YP_006771343.1 CDS O3M_18585 NC_018650.1 3788403 3788816 R COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; thioesterase complement(3788403..3788816) Escherichia coli O104:H4 str. 2009EL-2050 13690410 YP_006771344.1 CDS O3M_18590 NC_018650.1 3788819 3789565 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2,3-dihydroxybenzoate-2,3-dehydrogenase complement(3788819..3789565) Escherichia coli O104:H4 str. 2009EL-2050 13690411 YP_006771345.1 CDS O3M_18595 NC_018650.1 3789565 3790422 R COG1535 Isochorismate hydrolase; isochorismatase complement(3789565..3790422) Escherichia coli O104:H4 str. 2009EL-2050 13690412 YP_006771346.1 CDS entE NC_018650.1 3790436 3792046 R COG1021 Peptide arylation enzymes; enterobactin synthase subunit E complement(3790436..3792046) Escherichia coli O104:H4 str. 2009EL-2050 13690413 YP_006771347.1 CDS O3M_18605 NC_018650.1 3792056 3793231 R COG1169 Isochorismate synthase; isochorismate synthase EntC complement(3792056..3793231) Escherichia coli O104:H4 str. 2009EL-2050 13690414 YP_006771348.1 CDS O3M_18610 NC_018650.1 3793606 3794562 D COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component; iron-enterobactin transporter periplasmic binding protein 3793606..3794562 Escherichia coli O104:H4 str. 2009EL-2050 13690415 YP_006771349.1 CDS O3M_18615 NC_018650.1 3794566 3795816 R COG0477 Permeases of the major facilitator superfamily; enterobactin exporter EntS complement(3794566..3795816) Escherichia coli O104:H4 str. 2009EL-2050 13690416 YP_006771350.1 CDS O3M_18620 NC_018650.1 3795927 3796931 D COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-enterobactin transporter membrane protein 3795927..3796931 Escherichia coli O104:H4 str. 2009EL-2050 13690417 YP_006771351.1 CDS O3M_18625 NC_018650.1 3796928 3797920 D COG4779 ABC-type enterobactin transport system, permease component; iron-enterobactin transporter permease 3796928..3797920 Escherichia coli O104:H4 str. 2009EL-2050 13690418 YP_006771352.1 CDS O3M_18630 NC_018650.1 3797917 3798732 D COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-enterobactin transporter ATP-binding protein 3797917..3798732 Escherichia coli O104:H4 str. 2009EL-2050 13690419 YP_006771353.1 CDS O3M_18635 NC_018650.1 3798729 3799862 R COG3765 Chain length determinant protein; LPS O-antigen length regulator complement(3798729..3799862) Escherichia coli O104:H4 str. 2009EL-2050 13690420 YP_006771354.1 CDS entF NC_018650.1 3800078 3803959 R COG1020 Non-ribosomal peptide synthetase modules and related proteins; enterobactin synthase subunit F complement(3800078..3803959) Escherichia coli O104:H4 str. 2009EL-2050 13690421 YP_006771355.1 CDS O3M_18645 NC_018650.1 3803956 3804174 R COG3251 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3803956..3804174) Escherichia coli O104:H4 str. 2009EL-2050 13690422 YP_006771356.1 CDS O3M_18650 NC_018650.1 3804177 3805301 R COG2382 Enterochelin esterase and related enzymes; enterobactin/ferric enterobactin esterase complement(3804177..3805301) Escherichia coli O104:H4 str. 2009EL-2050 13690423 YP_006771357.1 CDS O3M_18655 NC_018650.1 3805622 3807862 D COG4771 Outer membrane receptor for ferrienterochelin and colicins; outer membrane receptor FepA 3805622..3807862 Escherichia coli O104:H4 str. 2009EL-2050 13690424 YP_006771358.1 CDS O3M_18660 NC_018650.1 3808028 3808657 D COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 3808028..3808657 Escherichia coli O104:H4 str. 2009EL-2050 13690425 YP_006771359.1 CDS O3M_18665 NC_018650.1 3808779 3808931 R regulatory peptide MokC complement(3808779..3808931) Escherichia coli O104:H4 str. 2009EL-2050 13690426 YP_006771360.1 CDS O3M_18670 NC_018650.1 3809442 3810554 R COG3385 FOG: Transposase and inactivated derivatives; transposase insL for insertion sequence IS186 complement(3809442..3810554) Escherichia coli O104:H4 str. 2009EL-2050 13690427 YP_006771361.1 CDS O3M_18675 NC_018650.1 3810631 3810783 R hypothetical protein complement(3810631..3810783) Escherichia coli O104:H4 str. 2009EL-2050 13690428 YP_006771362.1 CDS O3M_18680 NC_018650.1 3811049 3811150 R hypothetical protein complement(3811049..3811150) Escherichia coli O104:H4 str. 2009EL-2050 13690429 YP_006771363.1 CDS O3M_18685 NC_018650.1 3811225 3812343 D COG2170 Uncharacterized conserved protein; gamma-glutamyl:cysteine ligase 3811225..3812343 Escherichia coli O104:H4 str. 2009EL-2050 13690430 YP_006771364.1 CDS O3M_18690 NC_018650.1 3812409 3812657 D inner membrane protein 3812409..3812657 Escherichia coli O104:H4 str. 2009EL-2050 13690431 YP_006771365.1 CDS O3M_18695 NC_018650.1 3812722 3813090 D COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein 3812722..3813090 Escherichia coli O104:H4 str. 2009EL-2050 13690432 YP_006771366.1 CDS O3M_18700 NC_018650.1 3813184 3813837 D COG0778 Nitroreductase; dihydropteridine reductase 3813184..3813837 Escherichia coli O104:H4 str. 2009EL-2050 13690433 YP_006771367.1 CDS O3M_18705 NC_018650.1 3813945 3815192 D COG0668 Small-conductance mechanosensitive channel; mechanosensitive channel 3813945..3815192 Escherichia coli O104:H4 str. 2009EL-2050 13690434 YP_006771368.1 CDS O3M_18710 NC_018650.1 3815260 3816636 R COG1113 Gamma-aminobutyrate permease and related permeases; phenylalanine transporter complement(3815260..3816636) Escherichia coli O104:H4 str. 2009EL-2050 13690435 YP_006771369.1 CDS O3M_18715 NC_018650.1 3816738 3819881 R COG3696 Putative silver efflux pump; copper/silver efflux system, membrane component complement(3816738..3819881) Escherichia coli O104:H4 str. 2009EL-2050 13690436 YP_006771370.1 CDS O3M_18720 NC_018650.1 3819893 3821116 R COG0845 Membrane-fusion protein; copper/silver efflux system membrane fusion protein CusB complement(3819893..3821116) Escherichia coli O104:H4 str. 2009EL-2050 13690437 YP_006771371.1 CDS O3M_18725 NC_018650.1 3821132 3821464 R COG5569 Uncharacterized conserved protein; copper-binding protein complement(3821132..3821464) Escherichia coli O104:H4 str. 2009EL-2050 13690438 YP_006771372.1 CDS O3M_18730 NC_018650.1 3821488 3822870 R COG1538 Outer membrane protein; copper/silver efflux system outer membrane protein CusC complement(3821488..3822870) Escherichia coli O104:H4 str. 2009EL-2050 13690439 YP_006771373.1 CDS O3M_18735 NC_018650.1 3823027 3823710 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator CusR 3823027..3823710 Escherichia coli O104:H4 str. 2009EL-2050 13690440 YP_006771374.1 CDS O3M_18740 NC_018650.1 3823700 3825148 D COG0642 Signal transduction histidine kinase; sensor kinase CusS 3823700..3825148 Escherichia coli O104:H4 str. 2009EL-2050 13690441 YP_006771375.1 CDS O3M_18745 NC_018650.1 3825885 3827786 D COG3501 Uncharacterized protein conserved in bacteria; Rhs element Vgr protein 3825885..3827786 Escherichia coli O104:H4 str. 2009EL-2050 13690442 YP_006771376.1 CDS O3M_18750 NC_018650.1 3827814 3828275 D COG5435 Uncharacterized conserved protein; hypothetical protein 3827814..3828275 Escherichia coli O104:H4 str. 2009EL-2050 13690443 YP_006771377.1 CDS O3M_18755 NC_018650.1 3831823 3833157 D COG3209 Rhs family protein; Rhs core protein with extension 3831823..3833157 Escherichia coli O104:H4 str. 2009EL-2050 13690444 YP_006771378.1 CDS O3M_18760 NC_018650.1 3833154 3833405 D hypothetical protein 3833154..3833405 Escherichia coli O104:H4 str. 2009EL-2050 13690445 YP_006771379.1 CDS O3M_18765 NC_018650.1 3833520 3833831 D hypothetical protein 3833520..3833831 Escherichia coli O104:H4 str. 2009EL-2050 13690446 YP_006771380.1 CDS O3M_18770 NC_018650.1 3833935 3835071 D COG5433 Transposase; transposase 3833935..3835071 Escherichia coli O104:H4 str. 2009EL-2050 13690447 YP_006771381.1 CDS nfrB NC_018650.1 3835340 3837577 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; bacteriophage N4 adsorption protein B 3835340..3837577 Escherichia coli O104:H4 str. 2009EL-2050 13690448 YP_006771382.1 CDS O3M_18780 NC_018650.1 3837564 3840536 D COG0457 FOG: TPR repeat; bacteriophage N4 receptor, outer membrane subunit 3837564..3840536 Escherichia coli O104:H4 str. 2009EL-2050 13690449 YP_006771383.1 CDS O3M_18785 NC_018650.1 3840537 3841427 D hypothetical protein 3840537..3841427 Escherichia coli O104:H4 str. 2009EL-2050 13690450 YP_006771384.1 CDS O3M_18790 NC_018650.1 3841610 3842371 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator EnvY 3841610..3842371 Escherichia coli O104:H4 str. 2009EL-2050 13690451 YP_006771385.1 CDS O3M_18800 NC_018650.1 3842736 3843368 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator FimZ 3842736..3843368 Escherichia coli O104:H4 str. 2009EL-2050 13690453 YP_006771386.1 CDS O3M_18805 NC_018650.1 3843371 3843886 R COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein SfmF complement(3843371..3843886) Escherichia coli O104:H4 str. 2009EL-2050 13690454 YP_006771387.1 CDS fimH NC_018650.1 3843897 3844904 R fimbrial-like adhesin complement(3843897..3844904) Escherichia coli O104:H4 str. 2009EL-2050 13690455 YP_006771388.1 CDS O3M_18815 NC_018650.1 3844917 3847526 R COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein FimD complement(3844917..3847526) Escherichia coli O104:H4 str. 2009EL-2050 13690456 YP_006771389.1 CDS O3M_18820 NC_018650.1 3847557 3848249 R COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein FimC complement(3847557..3848249) Escherichia coli O104:H4 str. 2009EL-2050 13690457 YP_006771390.1 CDS O3M_18825 NC_018650.1 3848469 3849011 R COG3539 P pilus assembly protein, pilin FimA; type-1 fimbrial protein subunit A complement(3848469..3849011) Escherichia coli O104:H4 str. 2009EL-2050 13690458 YP_006771391.1 CDS O3M_18830 NC_018650.1 3849492 3850358 D COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3849492..3850358 Escherichia coli O104:H4 str. 2009EL-2050 13690459 YP_006771392.1 CDS O3M_18835 NC_018650.1 3850360 3850572 D COG2501 Uncharacterized conserved protein; hypothetical protein 3850360..3850572 Escherichia coli O104:H4 str. 2009EL-2050 13690460 YP_006771393.1 CDS O3M_18840 NC_018650.1 3850680 3851201 D COG1988 Predicted membrane-bound metal-dependent hydrolases; inner membrane protein YbcI 3850680..3851201 Escherichia coli O104:H4 str. 2009EL-2050 13690461 YP_006771394.1 CDS cysS NC_018650.1 3851237 3852622 R COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase complement(3851237..3852622) Escherichia coli O104:H4 str. 2009EL-2050 13690462 YP_006771395.1 CDS O3M_18850 NC_018650.1 3852796 3853290 D COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase B 3852796..3853290 Escherichia coli O104:H4 str. 2009EL-2050 13690463 YP_006771396.1 CDS O3M_18855 NC_018650.1 3853293 3854015 D COG2908 Uncharacterized protein conserved in bacteria; UDP-2,3-diacylglucosamine hydrolase 3853293..3854015 Escherichia coli O104:H4 str. 2009EL-2050 13690464 YP_006771397.1 CDS O3M_18860 NC_018650.1 3854133 3854642 D COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; phosphoribosylaminoimidazole carboxylase catalytic subunit 3854133..3854642 Escherichia coli O104:H4 str. 2009EL-2050 13690465 YP_006771398.1 CDS O3M_18865 NC_018650.1 3854639 3855706 D COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); phosphoribosylaminoimidazole carboxylase ATPase subunit 3854639..3855706 Escherichia coli O104:H4 str. 2009EL-2050 13690466 YP_006771399.1 CDS O3M_18870 NC_018650.1 3855901 3856794 R COG0549 Carbamate kinase; carbamate kinase complement(3855901..3856794) Escherichia coli O104:H4 str. 2009EL-2050 13690467 YP_006771400.1 CDS O3M_18875 NC_018650.1 3856791 3857606 R hypothetical protein complement(3856791..3857606) Escherichia coli O104:H4 str. 2009EL-2050 13690468 YP_006771401.1 CDS O3M_18880 NC_018650.1 3857617 3858876 R hypothetical protein complement(3857617..3858876) Escherichia coli O104:H4 str. 2009EL-2050 13690469 YP_006771402.1 CDS O3M_18885 NC_018650.1 3858886 3860553 R COG0074 Succinyl-CoA synthetase, alpha subunit; membrane protein FdrA complement(3858886..3860553) Escherichia coli O104:H4 str. 2009EL-2050 13690470 YP_006771403.1 CDS O3M_18890 NC_018650.1 3860870 3861919 D COG2055 Malate/L-lactate dehydrogenases; ureidoglycolate dehydrogenase 3860870..3861919 Escherichia coli O104:H4 str. 2009EL-2050 13690471 YP_006771404.1 CDS O3M_18895 NC_018650.1 3861941 3863176 D COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; allantoate amidohydrolase 3861941..3863176 Escherichia coli O104:H4 str. 2009EL-2050 13690472 YP_006771405.1 CDS O3M_18900 NC_018650.1 3863187 3863972 D COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization; hypothetical protein 3863187..3863972 Escherichia coli O104:H4 str. 2009EL-2050 13690473 YP_006771406.1 CDS O3M_18905 NC_018650.1 3864101 3865246 R COG1929 Glycerate kinase; glycerate kinase complement(3864101..3865246) Escherichia coli O104:H4 str. 2009EL-2050 13690474 YP_006771407.1 CDS O3M_18910 NC_018650.1 3865268 3866569 R COG2233 Xanthine/uracil permeases; uracil/xanthine transporter complement(3865268..3866569) Escherichia coli O104:H4 str. 2009EL-2050 13690475 YP_006771408.1 CDS O3M_18915 NC_018650.1 3866626 3867987 R COG0044 Dihydroorotase and related cyclic amidohydrolases; allantoinase complement(3866626..3867987) Escherichia coli O104:H4 str. 2009EL-2050 13690476 YP_006771409.1 CDS O3M_18920 NC_018650.1 3868047 3869501 R COG1953 Cytosine/uracil/thiamine/allantoin permeases; allantoin permease complement(3868047..3869501) Escherichia coli O104:H4 str. 2009EL-2050 13690477 YP_006771410.1 CDS O3M_18925 NC_018650.1 3869670 3870548 R COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; tartronate semialdehyde reductase complement(3869670..3870548) Escherichia coli O104:H4 str. 2009EL-2050 13690478 YP_006771411.1 CDS O3M_18930 NC_018650.1 3870648 3871424 R COG3622 Hydroxypyruvate isomerase; hydroxypyruvate isomerase complement(3870648..3871424) Escherichia coli O104:H4 str. 2009EL-2050 13690479 YP_006771412.1 CDS O3M_18935 NC_018650.1 3871437 3873218 R COG3960 Glyoxylate carboligase; glyoxylate carboligase complement(3871437..3873218) Escherichia coli O104:H4 str. 2009EL-2050 13690480 YP_006771413.1 CDS O3M_18940 NC_018650.1 3873308 3874123 R COG1414 Transcriptional regulator; DNA-binding transcriptional repressor AllR complement(3873308..3874123) Escherichia coli O104:H4 str. 2009EL-2050 13690481 YP_006771414.1 CDS O3M_18945 NC_018650.1 3874201 3874683 R COG3194 Ureidoglycolate hydrolase; ureidoglycolate hydrolase complement(3874201..3874683) Escherichia coli O104:H4 str. 2009EL-2050 13690482 YP_006771415.1 CDS O3M_18950 NC_018650.1 3874913 3875839 D COG0583 Transcriptional regulator; DNA-binding transcriptional activator AllS 3874913..3875839 Escherichia coli O104:H4 str. 2009EL-2050 13690483 YP_006771416.1 CDS O3M_18955 NC_018650.1 3875908 3877002 D COG2603 Predicted ATPase; tRNA 2-selenouridine synthase 3875908..3877002 Escherichia coli O104:H4 str. 2009EL-2050 13690484 YP_006771417.1 CDS O3M_18960 NC_018650.1 3877118 3877516 D regulator with homeodomain-like DNA binding domain 3877118..3877516 Escherichia coli O104:H4 str. 2009EL-2050 13690485 YP_006771418.1 CDS O3M_18965 NC_018650.1 3878003 3878494 R hypothetical protein complement(3878003..3878494) Escherichia coli O104:H4 str. 2009EL-2050 13690486 YP_006771419.1 CDS O3M_18970 NC_018650.1 3878475 3879185 R COG3209 Rhs family protein; rhs-like protein complement(3878475..3879185) Escherichia coli O104:H4 str. 2009EL-2050 13690487 YP_006771420.1 CDS O3M_18975 NC_018650.1 3879185 3879553 R hypothetical protein complement(3879185..3879553) Escherichia coli O104:H4 str. 2009EL-2050 13690488 YP_006771421.1 CDS O3M_18980 NC_018650.1 3879593 3883882 R COG3209 Rhs family protein; rhsD element protein complement(3879593..3883882) Escherichia coli O104:H4 str. 2009EL-2050 13690489 YP_006771422.1 CDS O3M_18985 NC_018650.1 3884312 3886726 R COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component; ABC transporter permease complement(3884312..3886726) Escherichia coli O104:H4 str. 2009EL-2050 13690490 YP_006771423.1 CDS O3M_18990 NC_018650.1 3886723 3887409 R COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component; ABC transporter ATP-binding protein complement(3886723..3887409) Escherichia coli O104:H4 str. 2009EL-2050 13690491 YP_006771424.1 CDS O3M_18995 NC_018650.1 3887377 3888003 D COG2755 Lysophospholipase L1 and related esterases; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 3887377..3888003 Escherichia coli O104:H4 str. 2009EL-2050 13690492 YP_006771425.1 CDS O3M_19000 NC_018650.1 3888032 3888802 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 3888032..3888802 Escherichia coli O104:H4 str. 2009EL-2050 13690493 YP_006771426.1 CDS O3M_19005 NC_018650.1 3888863 3889717 D COG3118 Thioredoxin domain-containing protein; thioredoxin-like protein 3888863..3889717 Escherichia coli O104:H4 str. 2009EL-2050 13690494 YP_006771427.1 CDS O3M_19010 NC_018650.1 3889780 3890559 R COG0390 ABC-type uncharacterized transport system, permease component; metal resistance protein complement(3889780..3890559) Escherichia coli O104:H4 str. 2009EL-2050 13690495 YP_006771428.1 CDS O3M_19015 NC_018650.1 3890546 3891223 R COG4619 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATP-binding protein complement(3890546..3891223) Escherichia coli O104:H4 str. 2009EL-2050 13690496 YP_006771429.1 CDS O3M_19020 NC_018650.1 3891369 3892286 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; protease 3891369..3892286 Escherichia coli O104:H4 str. 2009EL-2050 13690497 YP_006771430.1 CDS O3M_19025 NC_018650.1 3892283 3892741 D COG1585 Membrane protein implicated in regulation of membrane protease activity; nodulation efficiency family protein 3892283..3892741 Escherichia coli O104:H4 str. 2009EL-2050 13690498 YP_006771431.1 CDS O3M_19030 NC_018650.1 3892742 3893149 R COG0789 Predicted transcriptional regulators; DNA-binding transcriptional regulator CueR complement(3892742..3893149) Escherichia coli O104:H4 str. 2009EL-2050 13690499 YP_006771432.1 CDS O3M_19035 NC_018650.1 3893274 3894566 R COG0531 Amino acid transporters; transporter complement(3893274..3894566) Escherichia coli O104:H4 str. 2009EL-2050 13690500 YP_006771433.1 CDS O3M_19040 NC_018650.1 3894569 3895501 R COG2066 Glutaminase; glutaminase complement(3894569..3895501) Escherichia coli O104:H4 str. 2009EL-2050 13690501 YP_006771434.1 CDS copA NC_018650.1 3895763 3898267 D COG2217 Cation transport ATPase; copper exporting ATPase 3895763..3898267 Escherichia coli O104:H4 str. 2009EL-2050 13690502 YP_006771435.1 CDS O3M_19050 NC_018650.1 3898381 3898722 R COG3093 Plasmid maintenance system antidote protein; DNA-binding transcriptional regulator complement(3898381..3898722) Escherichia coli O104:H4 str. 2009EL-2050 13690503 YP_006771436.1 CDS O3M_19055 NC_018650.1 3898860 3899654 D COG3735 Uncharacterized protein conserved in bacteria; hypothetical protein 3898860..3899654 Escherichia coli O104:H4 str. 2009EL-2050 13690504 YP_006771437.1 CDS O3M_19060 NC_018650.1 3899858 3900337 D COG2606 Uncharacterized conserved protein; hypothetical protein 3899858..3900337 Escherichia coli O104:H4 str. 2009EL-2050 13690505 YP_006771438.1 CDS ushA NC_018650.1 3900374 3902026 R COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; bifunctional UDP-sugar hydrolase/5'-nucleotidase complement(3900374..3902026) Escherichia coli O104:H4 str. 2009EL-2050 13690506 YP_006771439.1 CDS O3M_19070 NC_018650.1 3902244 3903464 D COG0477 Permeases of the major facilitator superfamily; fosmidomycin efflux system, member of the major facilitator superfamily protein 3902244..3903464 Escherichia coli O104:H4 str. 2009EL-2050 13690507 YP_006771440.1 CDS O3M_19075 NC_018650.1 3903702 3905378 D COG4651 Kef-type K+ transport system, predicted NAD-binding component; cation:proton antiport protein 3903702..3905378 Escherichia coli O104:H4 str. 2009EL-2050 13690508 YP_006771441.1 CDS O3M_19080 NC_018650.1 3905511 3906815 R COG0524 Sugar kinases, ribokinase family; inosine/guanosine kinase complement(3905511..3906815) Escherichia coli O104:H4 str. 2009EL-2050 13690509 YP_006771442.1 CDS O3M_19085 NC_018650.1 3906967 3907926 D COG0657 Esterase/lipase; acetyl esterase 3906967..3907926 Escherichia coli O104:H4 str. 2009EL-2050 13690510 YP_006771443.1 CDS hemH NC_018650.1 3907923 3908885 R COG0276 Protoheme ferro-lyase (ferrochelatase); ferrochelatase complement(3907923..3908885) Escherichia coli O104:H4 str. 2009EL-2050 13690511 YP_006771444.1 CDS adk NC_018650.1 3909121 3909765 R COG0563 Adenylate kinase and related kinases; adenylate kinase complement(3909121..3909765) Escherichia coli O104:H4 str. 2009EL-2050 13690512 YP_006771445.1 CDS O3M_19100 NC_018650.1 3909946 3911820 R COG0326 Molecular chaperone, HSP90 family; heat shock protein 90 complement(3909946..3911820) Escherichia coli O104:H4 str. 2009EL-2050 13690513 YP_006771446.1 CDS recR NC_018650.1 3911930 3912535 R COG0353 Recombinational DNA repair protein (RecF pathway); recombination protein RecR complement(3911930..3912535) Escherichia coli O104:H4 str. 2009EL-2050 13690514 YP_006771447.1 CDS O3M_19110 NC_018650.1 3912535 3912864 R COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3912535..3912864) Escherichia coli O104:H4 str. 2009EL-2050 13690515 YP_006771448.1 CDS O3M_19115 NC_018650.1 3912917 3914848 R COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunits gamma and tau complement(3912917..3914848) Escherichia coli O104:H4 str. 2009EL-2050 13690516 YP_006771449.1 CDS O3M_19120 NC_018650.1 3914977 3915528 R COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine phosphoribosyltransferase complement(3914977..3915528) Escherichia coli O104:H4 str. 2009EL-2050 13690517 YP_006771450.1 CDS O3M_19125 NC_018650.1 3915681 3916058 R COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein complement(3915681..3916058) Escherichia coli O104:H4 str. 2009EL-2050 13690518 YP_006771451.1 CDS O3M_19130 NC_018650.1 3916128 3916655 D COG3923 Primosomal replication protein N''; primosomal replication protein N'' 3916128..3916655 Escherichia coli O104:H4 str. 2009EL-2050 13690519 YP_006771452.1 CDS O3M_19135 NC_018650.1 3916669 3916830 D hypothetical protein 3916669..3916830 Escherichia coli O104:H4 str. 2009EL-2050 13690520 YP_006771453.1 CDS O3M_19140 NC_018650.1 3916864 3917007 D hypothetical protein 3916864..3917007 Escherichia coli O104:H4 str. 2009EL-2050 13690521 YP_006771454.1 CDS O3M_19145 NC_018650.1 3917042 3920404 R COG3264 Small-conductance mechanosensitive channel; hypothetical protein complement(3917042..3920404) Escherichia coli O104:H4 str. 2009EL-2050 13690522 YP_006771455.1 CDS O3M_19150 NC_018650.1 3920532 3921179 R COG1309 Transcriptional regulator; DNA-binding transcriptional repressor AcrR complement(3920532..3921179) Escherichia coli O104:H4 str. 2009EL-2050 13690523 YP_006771456.1 CDS O3M_19155 NC_018650.1 3921321 3922514 D COG0845 Membrane-fusion protein; multidrug efflux system transporter AcrA 3921321..3922514 Escherichia coli O104:H4 str. 2009EL-2050 13690524 YP_006771457.1 CDS O3M_19160 NC_018650.1 3922537 3925686 D COG0841 Cation/multidrug efflux pump; multidrug efflux system protein AcrB 3922537..3925686 Escherichia coli O104:H4 str. 2009EL-2050 13690525 YP_006771458.1 CDS O3M_19165 NC_018650.1 3926232 3926606 D Hha toxicity attenuator 3926232..3926606 Escherichia coli O104:H4 str. 2009EL-2050 13690526 YP_006771459.1 CDS O3M_19170 NC_018650.1 3926632 3926850 D modulator of gene expression, with H-NS; hemolysin expression-modulating protein 3926632..3926850 Escherichia coli O104:H4 str. 2009EL-2050 13690527 YP_006771460.1 CDS O3M_19175 NC_018650.1 3927021 3927572 D COG0110 Acetyltransferase (isoleucine patch superfamily); maltose O-acetyltransferase 3927021..3927572 Escherichia coli O104:H4 str. 2009EL-2050 13690528 YP_006771461.1 CDS O3M_19180 NC_018650.1 3927688 3928158 D hypothetical protein 3927688..3928158 Escherichia coli O104:H4 str. 2009EL-2050 13690529 YP_006771462.1 CDS O3M_19185 NC_018650.1 3928322 3929872 D COG4943 Predicted signal transduction protein containing sensor and EAL domains; hypothetical protein 3928322..3929872 Escherichia coli O104:H4 str. 2009EL-2050 13690530 YP_006771463.1 CDS O3M_19190 NC_018650.1 3929914 3930267 R COG5507 Uncharacterized conserved protein; hypothetical protein complement(3929914..3930267) Escherichia coli O104:H4 str. 2009EL-2050 13690531 YP_006771464.1 CDS O3M_19195 NC_018650.1 3930568 3930957 D COG3695 Predicted methylated DNA-protein cysteine methyltransferase; methylated-DNA-[protein]-cysteine S-methyltransferase 3930568..3930957 Escherichia coli O104:H4 str. 2009EL-2050 13690532 YP_006771465.1 CDS O3M_19200 NC_018650.1 3930988 3931560 R COG3126 Uncharacterized protein conserved in bacteria; lipoprotein complement(3930988..3931560) Escherichia coli O104:H4 str. 2009EL-2050 13690533 YP_006771466.1 CDS O3M_19205 NC_018650.1 3931778 3932638 D COG1946 Acyl-CoA thioesterase; acyl-CoA thioesterase II 3931778..3932638 Escherichia coli O104:H4 str. 2009EL-2050 13690534 YP_006771467.1 CDS O3M_19210 NC_018650.1 3932687 3933973 R COG0004 Ammonia permease; ammonium transporter complement(3932687..3933973) Escherichia coli O104:H4 str. 2009EL-2050 13690535 YP_006771468.1 CDS O3M_19215 NC_018650.1 3934003 3934341 R COG0347 Nitrogen regulatory protein PII; glutamine synthetase complement(3934003..3934341) Escherichia coli O104:H4 str. 2009EL-2050 13690536 YP_006771469.1 CDS O3M_19220 NC_018650.1 3934522 3936303 R COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug transporter membrane\ATP-binding components complement(3934522..3936303) Escherichia coli O104:H4 str. 2009EL-2050 13690537 YP_006771470.1 CDS O3M_19225 NC_018650.1 3936296 3938068 R COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug transporter membrane\ATP-binding components complement(3936296..3938068) Escherichia coli O104:H4 str. 2009EL-2050 13690538 YP_006771471.1 CDS O3M_19230 NC_018650.1 3938098 3938556 R COG1522 Transcriptional regulators; LRP-like transcriptional regulator complement(3938098..3938556) Escherichia coli O104:H4 str. 2009EL-2050 13690539 YP_006771472.1 CDS O3M_19235 NC_018650.1 3938709 3939527 R COG0561 Predicted hydrolases of the HAD superfamily; thiamin pyrimidine pyrophosphate hydrolase complement(3938709..3939527) Escherichia coli O104:H4 str. 2009EL-2050 13690540 YP_006771473.1 CDS O3M_19240 NC_018650.1 3939627 3941327 D COG4533 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein 3939627..3941327 Escherichia coli O104:H4 str. 2009EL-2050 13690541 YP_006771474.1 CDS O3M_19245 NC_018650.1 3941392 3942087 D COG0603 Predicted PP-loop superfamily ATPase; queuosine biosynthesis protein QueC 3941392..3942087 Escherichia coli O104:H4 str. 2009EL-2050 13690542 YP_006771475.1 CDS O3M_19250 NC_018650.1 3942139 3942537 R COG0824 Predicted thioesterase; thioesterase superfamily protein complement(3942139..3942537) Escherichia coli O104:H4 str. 2009EL-2050 13690543 YP_006771476.1 CDS O3M_19255 NC_018650.1 3942631 3943002 R COG1555 DNA uptake protein and related DNA-binding proteins; hypothetical protein complement(3942631..3943002) Escherichia coli O104:H4 str. 2009EL-2050 13690544 YP_006771477.1 CDS O3M_19260 NC_018650.1 3943153 3945024 R COG0760 Parvulin-like peptidyl-prolyl isomerase; chaperone complement(3943153..3945024) Escherichia coli O104:H4 str. 2009EL-2050 13690545 YP_006771478.1 CDS O3M_19265 NC_018650.1 3945216 3945488 R COG0776 Bacterial nucleoid DNA-binding protein; transcriptional regulator HU subunit beta complement(3945216..3945488) Escherichia coli O104:H4 str. 2009EL-2050 13690546 YP_006771479.1 CDS O3M_19270 NC_018650.1 3945697 3948051 R COG0466 ATP-dependent Lon protease, bacterial type; DNA-binding ATP-dependent protease La complement(3945697..3948051) Escherichia coli O104:H4 str. 2009EL-2050 13690547 YP_006771480.1 CDS clpX NC_018650.1 3948239 3949513 R COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease ATP-binding subunit ClpX complement(3948239..3949513) Escherichia coli O104:H4 str. 2009EL-2050 13690548 YP_006771481.1 CDS O3M_19280 NC_018650.1 3949540 3949740 D hypothetical protein 3949540..3949740 Escherichia coli O104:H4 str. 2009EL-2050 13690549 YP_006771482.1 CDS clpP NC_018650.1 3949639 3950262 R COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease proteolytic subunit complement(3949639..3950262) Escherichia coli O104:H4 str. 2009EL-2050 13690550 YP_006771483.1 CDS tig NC_018650.1 3950508 3951806 R COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); trigger factor complement(3950508..3951806) Escherichia coli O104:H4 str. 2009EL-2050 13690551 YP_006771484.1 CDS O3M_19295 NC_018650.1 3951953 3952141 R hypothetical protein complement(3951953..3952141) Escherichia coli O104:H4 str. 2009EL-2050 13690552 YP_006771485.1 CDS O3M_19300 NC_018650.1 3952150 3952467 R COG0271 Stress-induced morphogen (activity unknown); transcriptional regulator BolA complement(3952150..3952467) Escherichia coli O104:H4 str. 2009EL-2050 13690553 YP_006771486.1 CDS O3M_19305 NC_018650.1 3952772 3953350 D COG3056 Uncharacterized lipoprotein; hypothetical protein 3952772..3953350 Escherichia coli O104:H4 str. 2009EL-2050 13690554 YP_006771487.1 CDS ampG NC_018650.1 3953394 3954869 D COG0477 Permeases of the major facilitator superfamily; muropeptide transporter 3953394..3954869 Escherichia coli O104:H4 str. 2009EL-2050 13690555 YP_006771488.1 CDS O3M_19315 NC_018650.1 3955329 3956276 D COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome o ubiquinol oxidase subunit II 3955329..3956276 Escherichia coli O104:H4 str. 2009EL-2050 13690556 YP_006771489.1 CDS O3M_19320 NC_018650.1 3956298 3958289 D COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome o ubiquinol oxidase subunit I 3956298..3958289 Escherichia coli O104:H4 str. 2009EL-2050 13690557 YP_006771490.1 CDS O3M_19325 NC_018650.1 3958279 3958893 D COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; cytochrome o ubiquinol oxidase subunit III 3958279..3958893 Escherichia coli O104:H4 str. 2009EL-2050 13690558 YP_006771491.1 CDS O3M_19330 NC_018650.1 3958893 3959222 D COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4; cytochrome o ubiquinol oxidase subunit IV 3958893..3959222 Escherichia coli O104:H4 str. 2009EL-2050 13690559 YP_006771492.1 CDS O3M_19335 NC_018650.1 3959234 3960124 D COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor); protoheme IX farnesyltransferase 3959234..3960124 Escherichia coli O104:H4 str. 2009EL-2050 13690560 YP_006771493.1 CDS O3M_19340 NC_018650.1 3960309 3960620 D COG4453 Uncharacterized protein conserved in bacteria; hypothetical protein 3960309..3960620 Escherichia coli O104:H4 str. 2009EL-2050 13690561 YP_006771494.1 CDS O3M_19345 NC_018650.1 3960604 3961146 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 3960604..3961146 Escherichia coli O104:H4 str. 2009EL-2050 13690562 YP_006771495.1 CDS O3M_19350 NC_018650.1 3961202 3962197 R COG0790 FOG: TPR repeat, SEL1 subfamily; zinc-dependent hydrolase complement(3961202..3962197) Escherichia coli O104:H4 str. 2009EL-2050 13690563 YP_006771496.1 CDS O3M_19355 NC_018650.1 3962545 3963909 D COG0477 Permeases of the major facilitator superfamily; major facilitator family transporter protein 3962545..3963909 Escherichia coli O104:H4 str. 2009EL-2050 13690564 YP_006771497.1 CDS O3M_19360 NC_018650.1 3964037 3964528 R COG1666 Uncharacterized protein conserved in bacteria; nucleotide-binding protein complement(3964037..3964528) Escherichia coli O104:H4 str. 2009EL-2050 13690565 YP_006771498.1 CDS O3M_19365 NC_018650.1 3964696 3965607 D COG1893 Ketopantoate reductase; 2-dehydropantoate 2-reductase 3964696..3965607 Escherichia coli O104:H4 str. 2009EL-2050 13690566 YP_006771499.1 CDS O3M_19370 NC_018650.1 3965570 3966160 D COG0693 Putative intracellular protease/amidase; oxidative-stress-resistance chaperone 3965570..3966160 Escherichia coli O104:H4 str. 2009EL-2050 13690567 YP_006771500.1 CDS O3M_19375 NC_018650.1 3966214 3967662 R COG0301 Thiamine biosynthesis ATP pyrophosphatase; tRNA s(4)U8 sulfurtransferase complement(3966214..3967662) Escherichia coli O104:H4 str. 2009EL-2050 13690568 YP_006771501.1 CDS O3M_19380 NC_018650.1 3967868 3968110 D COG1722 Exonuclease VII small subunit; exodeoxyribonuclease VII small subunit 3967868..3968110 Escherichia coli O104:H4 str. 2009EL-2050 13690569 YP_006771502.1 CDS O3M_19385 NC_018650.1 3968110 3969009 D COG0142 Geranylgeranyl pyrophosphate synthase; geranyltranstransferase 3968110..3969009 Escherichia coli O104:H4 str. 2009EL-2050 13690570 YP_006771503.1 CDS O3M_19390 NC_018650.1 3969034 3970896 D COG1154 Deoxyxylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 3969034..3970896 Escherichia coli O104:H4 str. 2009EL-2050 13690571 YP_006771504.1 CDS O3M_19395 NC_018650.1 3970951 3971925 D COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 3970951..3971925 Escherichia coli O104:H4 str. 2009EL-2050 13690572 YP_006771505.1 CDS O3M_19400 NC_018650.1 3971979 3972497 R COG1267 Phosphatidylglycerophosphatase A and related proteins; phosphatidylglycerophosphatase A complement(3971979..3972497) Escherichia coli O104:H4 str. 2009EL-2050 13690573 YP_006771506.1 CDS O3M_19405 NC_018650.1 3972475 3973452 R COG0611 Thiamine monophosphate kinase; thiamine monophosphate kinase complement(3972475..3973452) Escherichia coli O104:H4 str. 2009EL-2050 13690574 YP_006771507.1 CDS nusB NC_018650.1 3973530 3973949 R COG0781 Transcription termination factor; transcription antitermination protein NusB complement(3973530..3973949) Escherichia coli O104:H4 str. 2009EL-2050 13690575 YP_006771508.1 CDS ribH NC_018650.1 3973969 3974439 R COG0054 Riboflavin synthase beta-chain; 6,7-dimethyl-8-ribityllumazine synthase complement(3973969..3974439) Escherichia coli O104:H4 str. 2009EL-2050 13690576 YP_006771509.1 CDS ribD NC_018650.1 3974528 3975631 R COG0117 Pyrimidine deaminase; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase complement(3974528..3975631) Escherichia coli O104:H4 str. 2009EL-2050 13690577 YP_006771510.1 CDS nrdR NC_018650.1 3975635 3976084 R COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; transcriptional regulator NrdR complement(3975635..3976084) Escherichia coli O104:H4 str. 2009EL-2050 13690578 YP_006771511.1 CDS O3M_19440 NC_018650.1 3977073 3977957 D COG3248 Nucleoside-binding outer membrane protein; nucleoside-specific channel-forming protein Tsx 3977073..3977957 Escherichia coli O104:H4 str. 2009EL-2050 13690579 YP_006771512.1 CDS O3M_19445 NC_018650.1 3977998 3978120 R hypothetical protein complement(3977998..3978120) Escherichia coli O104:H4 str. 2009EL-2050 13690580 YP_006771513.1 CDS O3M_19450 NC_018650.1 3978134 3978481 R COG1403 Restriction endonuclease; hypothetical protein complement(3978134..3978481) Escherichia coli O104:H4 str. 2009EL-2050 13690581 YP_006771514.1 CDS secF NC_018650.1 3978610 3979581 R COG0341 Preprotein translocase subunit SecF; preprotein translocase subunit SecF complement(3978610..3979581) Escherichia coli O104:H4 str. 2009EL-2050 13690582 YP_006771515.1 CDS secD NC_018650.1 3979592 3981439 R COG0342 Preprotein translocase subunit SecD; preprotein translocase subunit SecD complement(3979592..3981439) Escherichia coli O104:H4 str. 2009EL-2050 13690583 YP_006771516.1 CDS yajC NC_018650.1 3981467 3981799 R COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC complement(3981467..3981799) Escherichia coli O104:H4 str. 2009EL-2050 13690584 YP_006771517.1 CDS tgt NC_018650.1 3981822 3982949 R COG0343 Queuine/archaeosine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase complement(3981822..3982949) Escherichia coli O104:H4 str. 2009EL-2050 13690585 YP_006771518.1 CDS queA NC_018650.1 3983005 3984075 R COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(3983005..3984075) Escherichia coli O104:H4 str. 2009EL-2050 13690586 YP_006771519.1 CDS O3M_19480 NC_018650.1 3984168 3984749 D COG3124 Uncharacterized protein conserved in bacteria; acyl carrier protein phosphodiesterase 3984168..3984749 Escherichia coli O104:H4 str. 2009EL-2050 13690587 YP_006771520.1 CDS O3M_19485 NC_018650.1 3984754 3986571 R COG0366 Glycosidases; maltodextrin glucosidase complement(3984754..3986571) Escherichia coli O104:H4 str. 2009EL-2050 13690588 YP_006771521.1 CDS proY NC_018650.1 3986727 3988100 R COG1113 Gamma-aminobutyrate permease and related permeases; proline-specific permease complement(3986727..3988100) Escherichia coli O104:H4 str. 2009EL-2050 13690589 YP_006771522.1 CDS O3M_19495 NC_018650.1 3988176 3989495 R COG1114 Branched-chain amino acid permeases; branched-chain amino acid transport system 2 carrier protein BrnQ complement(3988176..3989495) Escherichia coli O104:H4 str. 2009EL-2050 13690590 YP_006771523.1 CDS phoR NC_018650.1 3989902 3991197 R COG0642 Signal transduction histidine kinase; phosphate regulon sensor protein complement(3989902..3991197) Escherichia coli O104:H4 str. 2009EL-2050 13690591 YP_006771524.1 CDS O3M_19505 NC_018650.1 3991255 3991944 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator PhoB complement(3991255..3991944) Escherichia coli O104:H4 str. 2009EL-2050 13690592 YP_006771525.1 CDS O3M_19510 NC_018650.1 3992134 3993336 D COG0420 DNA repair exonuclease; exonuclease subunit SbcD 3992134..3993336 Escherichia coli O104:H4 str. 2009EL-2050 13690593 YP_006771526.1 CDS O3M_19515 NC_018650.1 3993333 3996476 D COG0419 ATPase involved in DNA repair; exonuclease subunit SbcC 3993333..3996476 Escherichia coli O104:H4 str. 2009EL-2050 13690594 YP_006771527.1 CDS O3M_19520 NC_018650.1 3996602 3997786 D COG2814 Arabinose efflux permease; MFS transport protein AraJ 3996602..3997786 Escherichia coli O104:H4 str. 2009EL-2050 13690595 YP_006771528.1 CDS O3M_19525 NC_018650.1 3997929 3998837 R COG1940 Transcriptional regulator/sugar kinase; fructokinase complement(3997929..3998837) Escherichia coli O104:H4 str. 2009EL-2050 13690596 YP_006771529.1 CDS O3M_19530 NC_018650.1 3998962 3999873 D COG2974 DNA recombination-dependent growth factor C; exonuclease RdgC 3998962..3999873 Escherichia coli O104:H4 str. 2009EL-2050 13690597 YP_006771530.1 CDS O3M_19535 NC_018650.1 3999951 4000313 R hypothetical protein complement(3999951..4000313) Escherichia coli O104:H4 str. 2009EL-2050 13690598 YP_006771531.1 CDS O3M_19540 NC_018650.1 4000574 4000858 R COG3123 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4000574..4000858) Escherichia coli O104:H4 str. 2009EL-2050 13690599 YP_006771532.1 CDS O3M_19545 NC_018650.1 4000930 4001607 R hypothetical protein complement(4000930..4001607) Escherichia coli O104:H4 str. 2009EL-2050 13690600 YP_006771533.1 CDS O3M_19550 NC_018650.1 4001865 4002056 R hypothetical protein complement(4001865..4002056) Escherichia coli O104:H4 str. 2009EL-2050 13690601 YP_006771534.1 CDS aroL NC_018650.1 4002106 4002630 R COG0703 Shikimate kinase; shikimate kinase complement(4002106..4002630) Escherichia coli O104:H4 str. 2009EL-2050 13690602 YP_006771535.1 CDS O3M_19560 NC_018650.1 4002813 4003271 R COG1671 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4002813..4003271) Escherichia coli O104:H4 str. 2009EL-2050 13690603 YP_006771536.1 CDS O3M_19565 NC_018650.1 4003391 4004200 D COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 4003391..4004200 Escherichia coli O104:H4 str. 2009EL-2050 13690604 YP_006771537.1 CDS adrA NC_018650.1 4004217 4005332 R COG2199 FOG: GGDEF domain; diguanylate cyclase AdrA complement(4004217..4005332) Escherichia coli O104:H4 str. 2009EL-2050 13690605 YP_006771538.1 CDS O3M_19575 NC_018650.1 4005434 4005754 R hypothetical protein complement(4005434..4005754) Escherichia coli O104:H4 str. 2009EL-2050 13690606 YP_006771539.1 CDS O3M_19580 NC_018650.1 4005873 4007288 R COG1785 Alkaline phosphatase; alkaline phosphatase complement(4005873..4007288) Escherichia coli O104:H4 str. 2009EL-2050 13690607 YP_006771540.1 CDS O3M_19585 NC_018650.1 4007389 4007649 R anti-RssB factor complement(4007389..4007649) Escherichia coli O104:H4 str. 2009EL-2050 13690608 YP_006771541.1 CDS ddl NC_018650.1 4008112 4009206 D D-alanine-D-alanine ligase A; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanyl-alanine synthetase A 4008112..4009206 Escherichia coli O104:H4 str. 2009EL-2050 13690609 YP_006771542.1 CDS O3M_19595 NC_018650.1 4009230 4009442 R hypothetical protein complement(4009230..4009442) Escherichia coli O104:H4 str. 2009EL-2050 13690610 YP_006771543.1 CDS O3M_19600 NC_018650.1 4009702 4010010 D hypothetical protein 4009702..4010010 Escherichia coli O104:H4 str. 2009EL-2050 13690611 YP_006771544.1 CDS O3M_19605 NC_018650.1 4010069 4011163 R DNA-binding transcriptional regulator complement(4010069..4011163) Escherichia coli O104:H4 str. 2009EL-2050 13690612 YP_006771545.1 CDS O3M_19610 NC_018650.1 4011176 4012396 R COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components; microcin B17 transporter complement(4011176..4012396) Escherichia coli O104:H4 str. 2009EL-2050 13690613 YP_006771546.1 CDS O3M_19615 NC_018650.1 4012748 4013905 D COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactam binding protein AmpH 4012748..4013905 Escherichia coli O104:H4 str. 2009EL-2050 13690614 YP_006771547.1 CDS O3M_19620 NC_018650.1 4013906 4014529 R COG2186 Transcriptional regulators; DNA-binding transcriptional regulator complement(4013906..4014529) Escherichia coli O104:H4 str. 2009EL-2050 13690615 YP_006771548.1 CDS O3M_19625 NC_018650.1 4014617 4017505 R COG3468 Type V secretory pathway, adhesin AidA; flagellin structural protein complement(4014617..4017505) Escherichia coli O104:H4 str. 2009EL-2050 13690616 YP_006771549.1 CDS O3M_19630 NC_018650.1 4018029 4019003 D COG0113 Delta-aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase 4018029..4019003 Escherichia coli O104:H4 str. 2009EL-2050 13690617 YP_006771550.1 CDS tauD NC_018650.1 4019109 4019960 R COG2175 Probable taurine catabolism dioxygenase; taurine dioxygenase complement(4019109..4019960) Escherichia coli O104:H4 str. 2009EL-2050 13690618 YP_006771551.1 CDS O3M_19640 NC_018650.1 4019957 4020784 R COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; taurine transporter subunit complement(4019957..4020784) Escherichia coli O104:H4 str. 2009EL-2050 13690619 YP_006771552.1 CDS tauB NC_018650.1 4020781 4021548 R COG4525 ABC-type taurine transport system, ATPase component; taurine transporter ATP-binding subunit complement(4020781..4021548) Escherichia coli O104:H4 str. 2009EL-2050 13690620 YP_006771553.1 CDS tauA NC_018650.1 4021561 4022523 R COG4521 ABC-type taurine transport system, periplasmic component; taurine transporter substrate binding subunit complement(4021561..4022523) Escherichia coli O104:H4 str. 2009EL-2050 13690621 YP_006771554.1 CDS O3M_19655 NC_018650.1 4023139 4023810 D COG2120 Uncharacterized proteins, LmbE homologs; hypothetical protein 4023139..4023810 Escherichia coli O104:H4 str. 2009EL-2050 13690622 YP_006771555.1 CDS O3M_19660 NC_018650.1 4023820 4025016 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; membrane-associated glycosyltransferase 4023820..4025016 Escherichia coli O104:H4 str. 2009EL-2050 13690623 YP_006771556.1 CDS O3M_19665 NC_018650.1 4025135 4025575 D COG0110 Acetyltransferase (isoleucine patch superfamily); transferase 4025135..4025575 Escherichia coli O104:H4 str. 2009EL-2050 13690624 YP_006771557.1 CDS O3M_19670 NC_018650.1 4025577 4026350 D hypothetical protein 4025577..4026350 Escherichia coli O104:H4 str. 2009EL-2050 13690625 YP_006771558.1 CDS O3M_19675 NC_018650.1 4026536 4026811 D COG1937 Uncharacterized protein conserved in bacteria; regulator protein FrmR 4026536..4026811 Escherichia coli O104:H4 str. 2009EL-2050 13690626 YP_006771559.1 CDS O3M_19680 NC_018650.1 4026846 4027955 D COG1062 Zn-dependent alcohol dehydrogenases, class III; S-(hydroxymethyl)glutathione dehydrogenase 4026846..4027955 Escherichia coli O104:H4 str. 2009EL-2050 13690627 YP_006771560.1 CDS O3M_19685 NC_018650.1 4028048 4028881 D COG0627 Predicted esterase; S-formylglutathione hydrolase 4028048..4028881 Escherichia coli O104:H4 str. 2009EL-2050 13690628 YP_006771561.1 CDS O3M_19690 NC_018650.1 4029108 4029647 R COG3122 Uncharacterized protein conserved in bacteria; nucleoprotein/polynucleotide-associated enzyme complement(4029108..4029647) Escherichia coli O104:H4 str. 2009EL-2050 13690629 YP_006771562.1 CDS O3M_19695 NC_018650.1 4029749 4030960 R COG0477 Permeases of the major facilitator superfamily; 3-hydroxyphenylpropionic transporter MhpT complement(4029749..4030960) Escherichia coli O104:H4 str. 2009EL-2050 13690630 YP_006771563.1 CDS O3M_19700 NC_018650.1 4031136 4032149 R COG0119 Isopropylmalate/homocitrate/citramalate synthases; 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase complement(4031136..4032149) Escherichia coli O104:H4 str. 2009EL-2050 13690631 YP_006771564.1 CDS O3M_19705 NC_018650.1 4032146 4033096 R COG4569 Acetaldehyde dehydrogenase (acetylating); acetaldehyde dehydrogenase complement(4032146..4033096) Escherichia coli O104:H4 str. 2009EL-2050 13690632 YP_006771565.1 CDS mhpD NC_018650.1 4033093 4033902 R COG3971 2-keto-4-pentenoate hydratase; 2-keto-4-pentenoate hydratase complement(4033093..4033902) Escherichia coli O104:H4 str. 2009EL-2050 13690633 YP_006771566.1 CDS O3M_19715 NC_018650.1 4033912 4034793 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase complement(4033912..4034793) Escherichia coli O104:H4 str. 2009EL-2050 13690634 YP_006771567.1 CDS mhpB NC_018650.1 4034796 4035740 R 3-(2,3-dihydroxyphenyl)propionate dioxygenase complement(4034796..4035740) Escherichia coli O104:H4 str. 2009EL-2050 13690635 YP_006771568.1 CDS mhpA NC_018650.1 4035742 4037406 R COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 3-(3-hydroxyphenyl)propionate hydroxylase complement(4035742..4037406) Escherichia coli O104:H4 str. 2009EL-2050 13690636 YP_006771569.1 CDS O3M_19730 NC_018650.1 4037483 4038430 D COG1414 Transcriptional regulator; DNA-binding transcriptional activator MhpR 4037483..4038430 Escherichia coli O104:H4 str. 2009EL-2050 13690637 YP_006771570.1 CDS lacI NC_018650.1 4038507 4039589 D COG1609 Transcriptional regulators; lac repressor 4038507..4039589 Escherichia coli O104:H4 str. 2009EL-2050 13690638 YP_006771571.1 CDS lacZ NC_018650.1 4039712 4042786 D COG3250 Beta-galactosidase/beta-glucuronidase; beta-D-galactosidase 4039712..4042786 Escherichia coli O104:H4 str. 2009EL-2050 13690639 YP_006771572.1 CDS lacY NC_018650.1 4042838 4044091 D COG0477 Permeases of the major facilitator superfamily; galactoside permease 4042838..4044091 Escherichia coli O104:H4 str. 2009EL-2050 13690640 YP_006771573.1 CDS lacA NC_018650.1 4044157 4044768 D COG0110 Acetyltransferase (isoleucine patch superfamily); galactoside O-acetyltransferase 4044157..4044768 Escherichia coli O104:H4 str. 2009EL-2050 13690641 YP_006771574.1 CDS cynX NC_018650.1 4044871 4046025 R COG2807 Cyanate permease; cyanate transporter complement(4044871..4046025) Escherichia coli O104:H4 str. 2009EL-2050 13690642 YP_006771575.1 CDS O3M_19760 NC_018650.1 4046058 4046528 R COG1513 Cyanate lyase; cyanate hydratase complement(4046058..4046528) Escherichia coli O104:H4 str. 2009EL-2050 13690643 YP_006771576.1 CDS O3M_19765 NC_018650.1 4046559 4047218 R COG0288 Carbonic anhydrase; carbonate dehydratase complement(4046559..4047218) Escherichia coli O104:H4 str. 2009EL-2050 13690644 YP_006771577.1 CDS O3M_19770 NC_018650.1 4047328 4048227 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator CynR 4047328..4048227 Escherichia coli O104:H4 str. 2009EL-2050 13690645 YP_006771578.1 CDS O3M_19775 NC_018650.1 4048267 4049550 R COG0402 Cytosine deaminase and related metal-dependent hydrolases; cytosine deaminase complement(4048267..4049550) Escherichia coli O104:H4 str. 2009EL-2050 13690646 YP_006771579.1 CDS codB NC_018650.1 4049540 4050799 R COG1457 Purine-cytosine permease and related proteins; cytosine permease complement(4049540..4050799) Escherichia coli O104:H4 str. 2009EL-2050 13690647 YP_006771580.1 CDS prpE NC_018650.1 4051225 4053111 R COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; propionyl-CoA synthetase complement(4051225..4053111) Escherichia coli O104:H4 str. 2009EL-2050 13690648 YP_006771581.1 CDS prpD NC_018650.1 4053151 4054602 R COG2079 Uncharacterized protein involved in propionate catabolism; 2-methylcitrate dehydratase complement(4053151..4054602) Escherichia coli O104:H4 str. 2009EL-2050 13690649 YP_006771582.1 CDS O3M_19795 NC_018650.1 4054636 4055805 R COG0372 Citrate synthase; methylcitrate synthase complement(4054636..4055805) Escherichia coli O104:H4 str. 2009EL-2050 13690650 YP_006771583.1 CDS prpB NC_018650.1 4055850 4056740 R COG2513 PEP phosphonomutase and related enzymes; 2-methylisocitrate lyase complement(4055850..4056740) Escherichia coli O104:H4 str. 2009EL-2050 13690651 YP_006771584.1 CDS O3M_19805 NC_018650.1 4056978 4058564 D COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains; propionate catabolism operon regulatory protein PrpR 4056978..4058564 Escherichia coli O104:H4 str. 2009EL-2050 13690652 YP_006771585.1 CDS O3M_19810 NC_018650.1 4058665 4058940 R hypothetical protein complement(4058665..4058940) Escherichia coli O104:H4 str. 2009EL-2050 13690653 YP_006771586.1 CDS O3M_19815 NC_018650.1 4059126 4059758 D COG1280 Putative threonine efflux protein; neutral amino-acid efflux system 4059126..4059758 Escherichia coli O104:H4 str. 2009EL-2050 13690654 YP_006771587.1 CDS O3M_19820 NC_018650.1 4059775 4060020 R hypothetical protein complement(4059775..4060020) Escherichia coli O104:H4 str. 2009EL-2050 13690655 YP_006771588.1 CDS O3M_19825 NC_018650.1 4060432 4061247 R hypothetical protein complement(4060432..4061247) Escherichia coli O104:H4 str. 2009EL-2050 13690657 YP_006771589.1 CDS O3M_19830 NC_018650.1 4061490 4062539 R COG1064 Zn-dependent alcohol dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein complement(4061490..4062539) Escherichia coli O104:H4 str. 2009EL-2050 13690658 YP_006771590.1 CDS O3M_19835 NC_018650.1 4062626 4063582 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease complement(4062626..4063582) Escherichia coli O104:H4 str. 2009EL-2050 13690659 YP_006771591.1 CDS O3M_19840 NC_018650.1 4063579 4064550 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; permease of transporter probably ribose specific complement(4063579..4064550) Escherichia coli O104:H4 str. 2009EL-2050 13690660 YP_006771592.1 CDS O3M_19845 NC_018650.1 4064543 4066027 R COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein complement(4064543..4066027) Escherichia coli O104:H4 str. 2009EL-2050 13690661 YP_006771593.1 CDS O3M_19850 NC_018650.1 4066076 4067062 R COG1879 ABC-type sugar transport system, periplasmic component; sugar-binding protein complement(4066076..4067062) Escherichia coli O104:H4 str. 2009EL-2050 13690662 YP_006771594.1 CDS O3M_19855 NC_018650.1 4067313 4067753 R COG4405 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4067313..4067753) Escherichia coli O104:H4 str. 2009EL-2050 13690663 YP_006771595.1 CDS O3M_19860 NC_018650.1 4068022 4069404 R COG0402 Cytosine deaminase and related metal-dependent hydrolases; deaminase complement(4068022..4069404) Escherichia coli O104:H4 str. 2009EL-2050 13690664 YP_006771596.1 CDS O3M_19865 NC_018650.1 4069414 4070364 R COG0549 Carbamate kinase; carbamate kinase complement(4069414..4070364) Escherichia coli O104:H4 str. 2009EL-2050 13690665 YP_006771597.1 CDS O3M_19870 NC_018650.1 4070507 4071925 R hypothetical protein complement(4070507..4071925) Escherichia coli O104:H4 str. 2009EL-2050 13690666 YP_006771598.1 CDS O3M_19875 NC_018650.1 4071925 4073472 R COG0074 Succinyl-CoA synthetase, alpha subunit; enzyme with acyl-CoA domain complement(4071925..4073472) Escherichia coli O104:H4 str. 2009EL-2050 13690667 YP_006771599.1 CDS O3M_19880 NC_018650.1 4073462 4074325 R hypothetical protein complement(4073462..4074325) Escherichia coli O104:H4 str. 2009EL-2050 13690668 YP_006771600.1 CDS O3M_19885 NC_018650.1 4074365 4074970 R COG0666 FOG: Ankyrin repeat; transcriptional regulator complement(4074365..4074970) Escherichia coli O104:H4 str. 2009EL-2050 13690669 YP_006771601.1 CDS O3M_19890 NC_018650.1 4075228 4075725 D inner membrane protein 4075228..4075725 Escherichia coli O104:H4 str. 2009EL-2050 13690670 YP_006771602.1 CDS O3M_19895 NC_018650.1 4075817 4076749 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 4075817..4076749 Escherichia coli O104:H4 str. 2009EL-2050 13690671 YP_006771603.1 CDS O3M_19900 NC_018650.1 4076791 4077879 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional regulator complement(4076791..4077879) Escherichia coli O104:H4 str. 2009EL-2050 13690672 YP_006771604.1 CDS O3M_19905 NC_018650.1 4078021 4082004 R COG5295 Autotransporter adhesin; AidA-I adhesin-like protein complement(4078021..4082004) Escherichia coli O104:H4 str. 2009EL-2050 13690673 YP_006771605.1 CDS O3M_19910 NC_018650.1 4082577 4084610 R COG1292 Choline-glycine betaine transporter; choline transport protein BetT complement(4082577..4084610) Escherichia coli O104:H4 str. 2009EL-2050 13690674 YP_006771606.1 CDS O3M_19915 NC_018650.1 4084739 4085326 D COG1309 Transcriptional regulator; transcriptional regulator BetI 4084739..4085326 Escherichia coli O104:H4 str. 2009EL-2050 13690675 YP_006771607.1 CDS O3M_19920 NC_018650.1 4085340 4086812 D COG1012 NAD-dependent aldehyde dehydrogenases; betaine aldehyde dehydrogenase 4085340..4086812 Escherichia coli O104:H4 str. 2009EL-2050 13690676 YP_006771608.1 CDS O3M_19925 NC_018650.1 4086826 4088496 D COG2303 Choline dehydrogenase and related flavoproteins; choline dehydrogenase 4086826..4088496 Escherichia coli O104:H4 str. 2009EL-2050 13690677 YP_006771609.1 CDS O3M_19930 NC_018650.1 4088709 4089374 D inner membrane protein 4088709..4089374 Escherichia coli O104:H4 str. 2009EL-2050 13690678 YP_006771610.1 CDS O3M_19935 NC_018650.1 4089620 4090315 R COG1556 Uncharacterized conserved protein; hypothetical protein complement(4089620..4090315) Escherichia coli O104:H4 str. 2009EL-2050 13690679 YP_006771611.1 CDS O3M_19940 NC_018650.1 4090308 4091735 R oxidoreductase subunit with NAD(P)-binding domain and ferridoxin-like domain; COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain; iron-sulfur cluster binding protein complement(4090308..4091735) Escherichia coli O104:H4 str. 2009EL-2050 13690680 YP_006771612.1 CDS O3M_19945 NC_018650.1 4091746 4092465 R COG0247 Fe-S oxidoreductase; oxidoreductase complement(4091746..4092465) Escherichia coli O104:H4 str. 2009EL-2050 13690681 YP_006771613.1 CDS O3M_19950 NC_018650.1 4092992 4093846 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator, ARAC-type complement(4092992..4093846) Escherichia coli O104:H4 str. 2009EL-2050 13690682 YP_006771614.1 CDS O3M_19955 NC_018650.1 4094072 4095397 D COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyridine nucleotide-disulfide oxidoreductase 4094072..4095397 Escherichia coli O104:H4 str. 2009EL-2050 13690683 YP_006771615.1 CDS O3M_19960 NC_018650.1 4095506 4095742 D hypothetical protein 4095506..4095742 Escherichia coli O104:H4 str. 2009EL-2050 13690684 YP_006771616.1 CDS O3M_19965 NC_018650.1 4095754 4096182 D COG3059 Predicted membrane protein; hypothetical protein 4095754..4096182 Escherichia coli O104:H4 str. 2009EL-2050 13690685 YP_006771617.1 CDS O3M_19970 NC_018650.1 4096220 4097200 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase complement(4096220..4097200) Escherichia coli O104:H4 str. 2009EL-2050 13690686 YP_006771618.1 CDS O3M_19975 NC_018650.1 4097199 4097546 D COG3059 Predicted membrane protein; hypothetical protein 4097199..4097546 Escherichia coli O104:H4 str. 2009EL-2050 13690687 YP_006771619.1 CDS O3M_19980 NC_018650.1 4098136 4098993 D COG2207 AraC-type DNA-binding domain-containing proteins; Putative transcriptional regulator ykgA 4098136..4098993 Escherichia coli O104:H4 str. 2009EL-2050 13690688 YP_006771620.1 CDS O3M_19985 NC_018650.1 4099114 4103367 R adhesin complement(4099114..4103367) Escherichia coli O104:H4 str. 2009EL-2050 13690689 YP_006771621.1 CDS O3M_19990 NC_018650.1 4104483 4104584 D hypothetical protein 4104483..4104584 Escherichia coli O104:H4 str. 2009EL-2050 13690690 YP_006771622.1 CDS rpmE2 NC_018650.1 4104948 4105211 D COG0254 Ribosomal protein L31; 50S ribosomal protein L31 4104948..4105211 Escherichia coli O104:H4 str. 2009EL-2050 13690691 YP_006771623.1 CDS rpmJ NC_018650.1 4105211 4105351 D COG0257 Ribosomal protein L36; 50S ribosomal protein L36 4105211..4105351 Escherichia coli O104:H4 str. 2009EL-2050 13690692 YP_006771624.1 CDS O3M_20005 NC_018650.1 4105386 4105613 R hypothetical protein complement(4105386..4105613) Escherichia coli O104:H4 str. 2009EL-2050 13690693 YP_006771625.1 CDS O3M_20010 NC_018650.1 4106388 4106978 D COG2771 DNA-binding HTH domain-containing proteins; transcriptional regulator 4106388..4106978 Escherichia coli O104:H4 str. 2009EL-2050 13690694 YP_006771626.1 CDS O3M_20015 NC_018650.1 4107053 4107640 D hypothetical protein 4107053..4107640 Escherichia coli O104:H4 str. 2009EL-2050 13690695 YP_006771627.1 CDS O3M_20020 NC_018650.1 4107698 4108366 D chaperone 4107698..4108366 Escherichia coli O104:H4 str. 2009EL-2050 13690696 YP_006771628.1 CDS O3M_20025 NC_018650.1 4108392 4110917 D hypothetical protein 4108392..4110917 Escherichia coli O104:H4 str. 2009EL-2050 13690697 YP_006771629.1 CDS O3M_20030 NC_018650.1 4110907 4112550 D hypothetical protein 4110907..4112550 Escherichia coli O104:H4 str. 2009EL-2050 13690698 YP_006771630.1 CDS O3M_20035 NC_018650.1 4112519 4113229 D hypothetical protein 4112519..4113229 Escherichia coli O104:H4 str. 2009EL-2050 13690699 YP_006771631.1 CDS O3M_20040 NC_018650.1 4113542 4113871 D COG0727 Predicted Fe-S-cluster oxidoreductase; ferredoxin 4113542..4113871 Escherichia coli O104:H4 str. 2009EL-2050 13690700 YP_006771632.1 CDS O3M_20045 NC_018650.1 4114119 4114733 R COG3477 Predicted periplasmic/secreted protein; hypothetical protein complement(4114119..4114733) Escherichia coli O104:H4 str. 2009EL-2050 13690701 YP_006771633.1 CDS O3M_20050 NC_018650.1 4115151 4115840 D COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; aldehyde oxidoreductase 2Fe-2S subunit 4115151..4115840 Escherichia coli O104:H4 str. 2009EL-2050 13690702 YP_006771634.1 CDS O3M_20055 NC_018650.1 4115837 4116793 D COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; oxidoreductase 4115837..4116793 Escherichia coli O104:H4 str. 2009EL-2050 13690703 YP_006771635.1 CDS O3M_20060 NC_018650.1 4116790 4118988 D COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; oxidoreductase with molybdenum-binding domain 4116790..4118988 Escherichia coli O104:H4 str. 2009EL-2050 13690704 YP_006771636.1 CDS O3M_20065 NC_018650.1 4118998 4119954 D COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 4118998..4119954 Escherichia coli O104:H4 str. 2009EL-2050 13690705 YP_006771637.1 CDS O3M_20070 NC_018650.1 4119933 4120343 D COG0583 Transcriptional regulator; transcriptional regulator 4119933..4120343 Escherichia coli O104:H4 str. 2009EL-2050 13690706 YP_006771638.1 CDS O3M_20075 NC_018650.1 4120630 4121907 D COG0582 Integrase; integrase 4120630..4121907 Escherichia coli O104:H4 str. 2009EL-2050 13690707 YP_006771639.1 CDS O3M_20080 NC_018650.1 4121988 4122299 R hypothetical protein complement(4121988..4122299) Escherichia coli O104:H4 str. 2009EL-2050 13690708 YP_006771640.1 CDS O3M_20085 NC_018650.1 4122353 4123333 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 4122353..4123333 Escherichia coli O104:H4 str. 2009EL-2050 13690709 YP_006771641.1 CDS O3M_20090 NC_018650.1 4123442 4123864 R COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein complement(4123442..4123864) Escherichia coli O104:H4 str. 2009EL-2050 13690710 YP_006771642.1 CDS O3M_20095 NC_018650.1 4123912 4125753 R hypothetical protein complement(4123912..4125753) Escherichia coli O104:H4 str. 2009EL-2050 13690711 YP_006771643.1 CDS O3M_20100 NC_018650.1 4126137 4127168 R hypothetical protein complement(4126137..4127168) Escherichia coli O104:H4 str. 2009EL-2050 13690712 YP_006771644.1 CDS O3M_20105 NC_018650.1 4127183 4127566 R hypothetical protein complement(4127183..4127566) Escherichia coli O104:H4 str. 2009EL-2050 13690713 YP_006771645.1 CDS O3M_20110 NC_018650.1 4127571 4127768 R hypothetical protein complement(4127571..4127768) Escherichia coli O104:H4 str. 2009EL-2050 13690714 YP_006771646.1 CDS O3M_20115 NC_018650.1 4128759 4129058 R hypothetical protein complement(4128759..4129058) Escherichia coli O104:H4 str. 2009EL-2050 13690715 YP_006771647.1 CDS O3M_20120 NC_018650.1 4129058 4129261 R hypothetical protein complement(4129058..4129261) Escherichia coli O104:H4 str. 2009EL-2050 13690716 YP_006771648.1 CDS O3M_20125 NC_018650.1 4129319 4129702 R hypothetical protein complement(4129319..4129702) Escherichia coli O104:H4 str. 2009EL-2050 13690717 YP_006771649.1 CDS O3M_20130 NC_018650.1 4129800 4130069 R hypothetical protein complement(4129800..4130069) Escherichia coli O104:H4 str. 2009EL-2050 13690718 YP_006771650.1 CDS O3M_20135 NC_018650.1 4130079 4130747 R hypothetical protein complement(4130079..4130747) Escherichia coli O104:H4 str. 2009EL-2050 13690719 YP_006771651.1 CDS O3M_20140 NC_018650.1 4132752 4133303 D COG1961 Site-specific recombinases, DNA invertase Pin homologs; resolvase domain-containing protein 4132752..4133303 Escherichia coli O104:H4 str. 2009EL-2050 13690720 YP_006771652.1 CDS O3M_20145 NC_018650.1 4133869 4134021 R hypothetical protein complement(4133869..4134021) Escherichia coli O104:H4 str. 2009EL-2050 13690721 YP_006771653.1 CDS proA NC_018650.1 4134818 4136071 R COG0014 Gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase complement(4134818..4136071) Escherichia coli O104:H4 str. 2009EL-2050 13690723 YP_006771654.1 CDS O3M_20155 NC_018650.1 4136083 4137186 R COG0263 Glutamate 5-kinase; gamma-glutamyl kinase complement(4136083..4137186) Escherichia coli O104:H4 str. 2009EL-2050 13690724 YP_006771655.1 CDS O3M_20160 NC_018650.1 4137474 4138529 D COG3203 Outer membrane protein (porin); outer membrane phosphoporin protein E 4137474..4138529 Escherichia coli O104:H4 str. 2009EL-2050 13690725 YP_006771656.1 CDS O3M_20165 NC_018650.1 4138568 4138969 R DNA-binding transcriptional regulator Crl complement(4138568..4138969) Escherichia coli O104:H4 str. 2009EL-2050 13690726 YP_006771657.1 CDS frsA NC_018650.1 4139027 4140271 R COG1073 Hydrolases of the alpha/beta superfamily; fermentation/respiration switch protein complement(4139027..4140271) Escherichia coli O104:H4 str. 2009EL-2050 13690727 YP_006771658.1 CDS O3M_20175 NC_018650.1 4140363 4140821 R COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; xanthine-guanine phosphoribosyltransferase complement(4140363..4140821) Escherichia coli O104:H4 str. 2009EL-2050 13690728 YP_006771659.1 CDS O3M_20180 NC_018650.1 4141082 4142539 D COG2195 Di- and tripeptidases; aminoacyl-histidine dipeptidase 4141082..4142539 Escherichia coli O104:H4 str. 2009EL-2050 13690729 YP_006771660.1 CDS prfH NC_018650.1 4142596 4143210 R COG1186 Protein chain release factor B; peptide chain release factor-like protein complement(4142596..4143210) Escherichia coli O104:H4 str. 2009EL-2050 13690730 YP_006771661.1 CDS O3M_20190 NC_018650.1 4143207 4144346 R COG1690 Uncharacterized conserved protein; hypothetical protein complement(4143207..4144346) Escherichia coli O104:H4 str. 2009EL-2050 13690731 YP_006771662.1 CDS O3M_20195 NC_018650.1 4144592 4145044 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acyltransferase complement(4144592..4145044) Escherichia coli O104:H4 str. 2009EL-2050 13690732 YP_006771663.1 CDS O3M_20200 NC_018650.1 4145041 4146096 R COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase IV complement(4145041..4146096) Escherichia coli O104:H4 str. 2009EL-2050 13690733 YP_006771664.1 CDS O3M_20205 NC_018650.1 4146167 4146952 R COG1360 Flagellar motor protein; hypothetical protein complement(4146167..4146952) Escherichia coli O104:H4 str. 2009EL-2050 13690734 YP_006771665.1 CDS O3M_20210 NC_018650.1 4146897 4148636 D COG1298 Flagellar biosynthesis pathway, component FlhA; flagellar system protein 4146897..4148636 Escherichia coli O104:H4 str. 2009EL-2050 13690735 YP_006771666.1 CDS O3M_20215 NC_018650.1 4148741 4149019 D hypothetical protein 4148741..4149019 Escherichia coli O104:H4 str. 2009EL-2050 13690736 YP_006771667.1 CDS O3M_20220 NC_018650.1 4149012 4149368 D COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters; HicB protein 4149012..4149368 Escherichia coli O104:H4 str. 2009EL-2050 13690737 YP_006771668.1 CDS O3M_20225 NC_018650.1 4149425 4150174 R COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hydrolase complement(4149425..4150174) Escherichia coli O104:H4 str. 2009EL-2050 13690738 YP_006771669.1 CDS O3M_20230 NC_018650.1 4150384 4150644 D COG3077 DNA-damage-inducible protein J; DNA-damage-inducible protein J 4150384..4150644 Escherichia coli O104:H4 str. 2009EL-2050 13690739 YP_006771670.1 CDS O3M_20235 NC_018650.1 4150647 4150925 D COG3041 Uncharacterized protein conserved in bacteria; toxin of the YafQ-DinJ toxin-antitoxin system 4150647..4150925 Escherichia coli O104:H4 str. 2009EL-2050 13690740 YP_006771671.1 CDS O3M_20240 NC_018650.1 4151081 4151821 D COG3034 Uncharacterized protein conserved in bacteria; hypothetical protein 4151081..4151821 Escherichia coli O104:H4 str. 2009EL-2050 13690741 YP_006771672.1 CDS O3M_20245 NC_018650.1 4151792 4152559 R COG0121 Predicted glutamine amidotransferase; amidotransferase complement(4151792..4152559) Escherichia coli O104:H4 str. 2009EL-2050 13690742 YP_006771673.1 CDS gmhA NC_018650.1 4152765 4153343 R COG0279 Phosphoheptose isomerase; phosphoheptose isomerase complement(4152765..4153343) Escherichia coli O104:H4 str. 2009EL-2050 13690743 YP_006771674.1 CDS fadE NC_018650.1 4153583 4156027 D COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 4153583..4156027 Escherichia coli O104:H4 str. 2009EL-2050 13690744 YP_006771675.1 CDS O3M_20260 NC_018650.1 4156070 4156543 R C-lysozyme inhibitor complement(4156070..4156543) Escherichia coli O104:H4 str. 2009EL-2050 13690745 YP_006771676.1 CDS O3M_20265 NC_018650.1 4156697 4157467 D COG0388 Predicted amidohydrolase; C-N hydrolase family amidase 4156697..4157467 Escherichia coli O104:H4 str. 2009EL-2050 13690746 YP_006771677.1 CDS O3M_20270 NC_018650.1 4157509 4158570 R COG5433 Transposase; transposase complement(4157509..4158570) Escherichia coli O104:H4 str. 2009EL-2050 13690747 YP_006771678.1 CDS O3M_20285 NC_018650.1 4160055 4160537 R hypothetical protein complement(4160055..4160537) Escherichia coli O104:H4 str. 2009EL-2050 13690748 YP_006771679.1 CDS O3M_20290 NC_018650.1 4160521 4161711 R COG3209 Rhs family protein; Rhs Core protein complement(4160521..4161711) Escherichia coli O104:H4 str. 2009EL-2050 13690749 YP_006771680.1 CDS O3M_20295 NC_018650.1 4161680 4164184 R COG3209 Rhs family protein; Rhs core protein complement(4161680..4164184) Escherichia coli O104:H4 str. 2009EL-2050 13690750 YP_006771681.1 CDS O3M_20300 NC_018650.1 4164260 4166401 R COG3501 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4164260..4166401) Escherichia coli O104:H4 str. 2009EL-2050 13690751 YP_006771682.1 CDS O3M_20305 NC_018650.1 4166611 4167129 R COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein complement(4166611..4167129) Escherichia coli O104:H4 str. 2009EL-2050 13690752 YP_006771683.1 CDS O3M_20310 NC_018650.1 4167256 4167399 R hypothetical protein complement(4167256..4167399) Escherichia coli O104:H4 str. 2009EL-2050 13690753 YP_006771684.1 CDS O3M_20315 NC_018650.1 4167826 4168326 D COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 4167826..4168326 Escherichia coli O104:H4 str. 2009EL-2050 13690754 YP_006771685.1 CDS O3M_20320 NC_018650.1 4168361 4168585 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 4168361..4168585 Escherichia coli O104:H4 str. 2009EL-2050 13690755 YP_006771686.1 CDS O3M_20325 NC_018650.1 4168636 4170111 D COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 4168636..4170111 Escherichia coli O104:H4 str. 2009EL-2050 13690756 YP_006771687.1 CDS O3M_20330 NC_018650.1 4170118 4170531 D COG3518 Uncharacterized protein conserved in bacteria; hypothetical protein 4170118..4170531 Escherichia coli O104:H4 str. 2009EL-2050 13690757 YP_006771688.1 CDS O3M_20335 NC_018650.1 4170535 4172385 D COG3519 Uncharacterized protein conserved in bacteria; type VI secretion system protein ImpG 4170535..4172385 Escherichia coli O104:H4 str. 2009EL-2050 13690758 YP_006771689.1 CDS O3M_20340 NC_018650.1 4172349 4173431 D COG3520 Uncharacterized protein conserved in bacteria; hypothetical protein 4172349..4173431 Escherichia coli O104:H4 str. 2009EL-2050 13690759 YP_006771690.1 CDS O3M_20345 NC_018650.1 4173456 4174736 D COG3456 Uncharacterized conserved protein, contains FHA domain; type VI secretion system protein ImpI 4173456..4174736 Escherichia coli O104:H4 str. 2009EL-2050 13690760 YP_006771691.1 CDS O3M_20350 NC_018650.1 4174733 4175257 D COG3521 Uncharacterized protein conserved in bacteria; lipoprotein 4174733..4175257 Escherichia coli O104:H4 str. 2009EL-2050 13690761 YP_006771692.1 CDS O3M_20355 NC_018650.1 4175260 4176591 D COG3522 Uncharacterized protein conserved in bacteria; hypothetical protein 4175260..4176591 Escherichia coli O104:H4 str. 2009EL-2050 13690762 YP_006771693.1 CDS O3M_20360 NC_018650.1 4176596 4177357 D COG3455 Uncharacterized protein conserved in bacteria; membrane protein Aec26 4176596..4177357 Escherichia coli O104:H4 str. 2009EL-2050 13690763 YP_006771694.1 CDS O3M_20365 NC_018650.1 4177366 4180125 D COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp proteinase ATP-binding subunit 4177366..4180125 Escherichia coli O104:H4 str. 2009EL-2050 13690764 YP_006771695.1 CDS O3M_20370 NC_018650.1 4180122 4180865 D hypothetical protein 4180122..4180865 Escherichia coli O104:H4 str. 2009EL-2050 13690765 YP_006771696.1 CDS O3M_20375 NC_018650.1 4180870 4182285 D COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 4180870..4182285 Escherichia coli O104:H4 str. 2009EL-2050 13690766 YP_006771697.1 CDS O3M_20380 NC_018650.1 4182304 4185828 D COG3523 Uncharacterized protein conserved in bacteria; IcmF-like protein 4182304..4185828 Escherichia coli O104:H4 str. 2009EL-2050 13690767 YP_006771698.1 CDS O3M_20385 NC_018650.1 4185839 4187191 D COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 4185839..4187191 Escherichia coli O104:H4 str. 2009EL-2050 13690768 YP_006771699.1 CDS O3M_20390 NC_018650.1 4187215 4187697 D COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein 4187215..4187697 Escherichia coli O104:H4 str. 2009EL-2050 13690769 YP_006771700.1 CDS O3M_20395 NC_018650.1 4187741 4188655 D hypothetical protein 4187741..4188655 Escherichia coli O104:H4 str. 2009EL-2050 13690770 YP_006771701.1 CDS O3M_20400 NC_018650.1 4188665 4189144 D hypothetical protein 4188665..4189144 Escherichia coli O104:H4 str. 2009EL-2050 13690771 YP_006771702.1 CDS O3M_20405 NC_018650.1 4189281 4190066 R aminopeptidase complement(4189281..4190066) Escherichia coli O104:H4 str. 2009EL-2050 13690772 YP_006771703.1 CDS O3M_20410 NC_018650.1 4190602 4191333 R COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; DNA polymerase III subunit epsilon complement(4190602..4191333) Escherichia coli O104:H4 str. 2009EL-2050 13690774 YP_006771704.1 CDS rnhA NC_018650.1 4191398 4191865 D COG0328 Ribonuclease HI; ribonuclease H 4191398..4191865 Escherichia coli O104:H4 str. 2009EL-2050 13690775 YP_006771705.1 CDS O3M_20420 NC_018650.1 4191862 4192584 R COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase complement(4191862..4192584) Escherichia coli O104:H4 str. 2009EL-2050 13690776 YP_006771706.1 CDS O3M_20425 NC_018650.1 4192618 4193373 D COG0491 Zn-dependent hydrolases, including glyoxylases; hydroxyacylglutathione hydrolase 4192618..4193373 Escherichia coli O104:H4 str. 2009EL-2050 13690777 YP_006771707.1 CDS mltD NC_018650.1 4193445 4194803 D COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); membrane-bound lytic murein transglycosylase D 4193445..4194803 Escherichia coli O104:H4 str. 2009EL-2050 13690778 YP_006771708.1 CDS O3M_20435 NC_018650.1 4194851 4195621 R COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase complement(4194851..4195621) Escherichia coli O104:H4 str. 2009EL-2050 13690779 YP_006771709.1 CDS O3M_20440 NC_018650.1 4195699 4196499 R COG3021 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4195699..4196499) Escherichia coli O104:H4 str. 2009EL-2050 13690780 YP_006771710.1 CDS O3M_20445 NC_018650.1 4196740 4197654 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 4196740..4197654 Escherichia coli O104:H4 str. 2009EL-2050 13690781 YP_006771711.1 CDS dkgB NC_018650.1 4197651 4198454 R COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-diketo-D-gluconate reductase B complement(4197651..4198454) Escherichia coli O104:H4 str. 2009EL-2050 13690782 YP_006771712.1 CDS O3M_20455 NC_018650.1 4204353 4204925 R COG0241 Histidinol phosphatase and related phosphatases; D,D-heptose 1,7-bisphosphate phosphatase complement(4204353..4204925) Escherichia coli O104:H4 str. 2009EL-2050 13691518 YP_006771713.1 CDS metN NC_018650.1 4205113 4206144 D COG1135 ABC-type metal ion transport system, ATPase component; DL-methionine transporter ATP-binding subunit 4205113..4206144 Escherichia coli O104:H4 str. 2009EL-2050 13691519 YP_006771714.1 CDS O3M_20465 NC_018650.1 4206137 4206790 D COG2011 ABC-type metal ion transport system, permease component; DL-methionine transporter permease 4206137..4206790 Escherichia coli O104:H4 str. 2009EL-2050 13691520 YP_006771715.1 CDS metQ NC_018650.1 4206830 4207645 D COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; DL-methionine transporter substrate-binding subunit 4206830..4207645 Escherichia coli O104:H4 str. 2009EL-2050 13691521 YP_006771716.1 CDS rcsF NC_018650.1 4207763 4208167 D outer membrane lipoprotein 4207763..4208167 Escherichia coli O104:H4 str. 2009EL-2050 13691522 YP_006771717.1 CDS O3M_20480 NC_018650.1 4208164 4208871 D COG1720 Uncharacterized conserved protein; hypothetical protein 4208164..4208871 Escherichia coli O104:H4 str. 2009EL-2050 13691523 YP_006771718.1 CDS O3M_20485 NC_018650.1 4208983 4210701 D COG0442 Prolyl-tRNA synthetase; prolyl-tRNA synthetase 4208983..4210701 Escherichia coli O104:H4 str. 2009EL-2050 13691524 YP_006771719.1 CDS O3M_20490 NC_018650.1 4210754 4211335 D COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 4210754..4211335 Escherichia coli O104:H4 str. 2009EL-2050 13691525 YP_006771720.1 CDS O3M_20495 NC_018650.1 4211341 4211577 D hypothetical protein 4211341..4211577 Escherichia coli O104:H4 str. 2009EL-2050 13691526 YP_006771721.1 CDS O3M_20500 NC_018650.1 4211781 4212761 R COG3547 Transposase and inactivated derivatives; IS621 transposase complement(4211781..4212761) Escherichia coli O104:H4 str. 2009EL-2050 13691527 YP_006771722.1 CDS O3M_20505 NC_018650.1 4213011 4213721 R COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance; copper homeostasis and adhesion lipoprotein complement(4213011..4213721) Escherichia coli O104:H4 str. 2009EL-2050 13691528 YP_006771723.1 CDS O3M_20510 NC_018650.1 4213735 4214157 R COG1186 Protein chain release factor B; hypothetical protein complement(4213735..4214157) Escherichia coli O104:H4 str. 2009EL-2050 13691529 YP_006771724.1 CDS O3M_20515 NC_018650.1 4214154 4214699 R COG4681 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4214154..4214699) Escherichia coli O104:H4 str. 2009EL-2050 13691530 YP_006771725.1 CDS O3M_20520 NC_018650.1 4214865 4215065 D hypothetical protein 4214865..4215065 Escherichia coli O104:H4 str. 2009EL-2050 13691531 YP_006771726.1 CDS O3M_20525 NC_018650.1 4215052 4215312 D COG4568 Transcriptional antiterminator; Rho-binding antiterminator 4215052..4215312 Escherichia coli O104:H4 str. 2009EL-2050 13691532 YP_006771727.1 CDS tilS NC_018650.1 4215361 4216659 R COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile)-lysidine synthetase complement(4215361..4216659) Escherichia coli O104:H4 str. 2009EL-2050 13691533 YP_006771728.1 CDS O3M_20535 NC_018650.1 4216724 4217113 R COG0346 Lactoylglutathione lyase and related lyases; lyase complement(4216724..4217113) Escherichia coli O104:H4 str. 2009EL-2050 13691534 YP_006771729.1 CDS O3M_20540 NC_018650.1 4217170 4219311 R COG1982 Arginine/lysine/ornithine decarboxylases; lysine decarboxylase LdcC complement(4217170..4219311) Escherichia coli O104:H4 str. 2009EL-2050 13691535 YP_006771730.1 CDS O3M_20545 NC_018650.1 4219410 4220369 R COG0825 Acetyl-CoA carboxylase alpha subunit; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(4219410..4220369) Escherichia coli O104:H4 str. 2009EL-2050 13691536 YP_006771731.1 CDS dnaE NC_018650.1 4220382 4223864 R COG0587 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha complement(4220382..4223864) Escherichia coli O104:H4 str. 2009EL-2050 13691537 YP_006771732.1 CDS rnhB NC_018650.1 4223901 4224497 R COG0164 Ribonuclease HII; ribonuclease HII complement(4223901..4224497) Escherichia coli O104:H4 str. 2009EL-2050 13691538 YP_006771733.1 CDS lpxB NC_018650.1 4224494 4225642 R COG0763 Lipid A disaccharide synthetase; lipid-A-disaccharide synthase complement(4224494..4225642) Escherichia coli O104:H4 str. 2009EL-2050 13691539 YP_006771734.1 CDS O3M_20565 NC_018650.1 4225642 4226430 R COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; UDP-N-acetylglucosamine acyltransferase complement(4225642..4226430) Escherichia coli O104:H4 str. 2009EL-2050 13691540 YP_006771735.1 CDS fabZ NC_018650.1 4226434 4226889 R COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; (3R)-hydroxymyristoyl-ACP dehydratase complement(4226434..4226889) Escherichia coli O104:H4 str. 2009EL-2050 13691541 YP_006771736.1 CDS lpxD NC_018650.1 4226994 4228019 R COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(4226994..4228019) Escherichia coli O104:H4 str. 2009EL-2050 13691542 YP_006771737.1 CDS O3M_20580 NC_018650.1 4228023 4228508 R COG2825 Outer membrane protein; periplasmic chaperone complement(4228023..4228508) Escherichia coli O104:H4 str. 2009EL-2050 13691543 YP_006771738.1 CDS O3M_20585 NC_018650.1 4228630 4231062 R COG4775 Outer membrane protein/protective antigen OMA87; outer membrane protein assembly factor YaeT complement(4228630..4231062) Escherichia coli O104:H4 str. 2009EL-2050 13691544 YP_006771739.1 CDS O3M_20590 NC_018650.1 4231092 4232444 R COG0750 Predicted membrane-associated Zn-dependent proteases 1; zinc metallopeptidase RseP complement(4231092..4232444) Escherichia coli O104:H4 str. 2009EL-2050 13691545 YP_006771740.1 CDS cdsA NC_018650.1 4232456 4233313 R COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthase complement(4232456..4233313) Escherichia coli O104:H4 str. 2009EL-2050 13691546 YP_006771741.1 CDS O3M_20600 NC_018650.1 4233326 4234084 R COG0020 Undecaprenyl pyrophosphate synthase; undecaprenyl pyrophosphate synthase complement(4233326..4234084) Escherichia coli O104:H4 str. 2009EL-2050 13691547 YP_006771742.1 CDS O3M_20605 NC_018650.1 4234273 4235469 R COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(4234273..4235469) Escherichia coli O104:H4 str. 2009EL-2050 13691548 YP_006771743.1 CDS frr NC_018650.1 4235561 4236118 R COG0233 Ribosome recycling factor; ribosome recycling factor complement(4235561..4236118) Escherichia coli O104:H4 str. 2009EL-2050 13691549 YP_006771744.1 CDS pyrH NC_018650.1 4236410 4237135 R COG0528 Uridylate kinase; uridylate kinase complement(4236410..4237135) Escherichia coli O104:H4 str. 2009EL-2050 13691550 YP_006771745.1 CDS tsf NC_018650.1 4237282 4238133 R COG0264 Translation elongation factor Ts; elongation factor Ts complement(4237282..4238133) Escherichia coli O104:H4 str. 2009EL-2050 13691551 YP_006771746.1 CDS rpsB NC_018650.1 4238391 4239116 R COG0052 Ribosomal protein S2; 30S ribosomal protein S2 complement(4238391..4239116) Escherichia coli O104:H4 str. 2009EL-2050 13691552 YP_006771747.1 CDS O3M_20630 NC_018650.1 4239484 4240278 D COG0024 Methionine aminopeptidase; methionine aminopeptidase 4239484..4240278 Escherichia coli O104:H4 str. 2009EL-2050 13691553 YP_006771748.1 CDS O3M_20635 NC_018650.1 4240340 4243012 D COG2844 UTP:GlnB (protein PII) uridylyltransferase; PII uridylyl-transferase 4240340..4243012 Escherichia coli O104:H4 str. 2009EL-2050 13691554 YP_006771749.1 CDS dapD NC_018650.1 4243043 4243867 D COG2171 Tetrahydrodipicolinate N-succinyltransferase; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 4243043..4243867 Escherichia coli O104:H4 str. 2009EL-2050 13691555 YP_006771750.1 CDS O3M_20645 NC_018650.1 4244182 4244568 D hypothetical protein 4244182..4244568 Escherichia coli O104:H4 str. 2009EL-2050 13691556 YP_006771751.1 CDS O3M_20650 NC_018650.1 4244657 4245814 R COG3835 Sugar diacid utilization regulator; carbohydrate diacid transcriptional activator CdaR complement(4244657..4245814) Escherichia coli O104:H4 str. 2009EL-2050 13691557 YP_006771752.1 CDS O3M_20655 NC_018650.1 4245969 4247393 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease complement(4245969..4247393) Escherichia coli O104:H4 str. 2009EL-2050 13691558 YP_006771753.1 CDS dgt NC_018650.1 4247523 4249040 R COG0232 dGTP triphosphohydrolase; deoxyguanosinetriphosphate triphosphohydrolase complement(4247523..4249040) Escherichia coli O104:H4 str. 2009EL-2050 13691559 YP_006771754.1 CDS O3M_20665 NC_018650.1 4249124 4249822 D COG0775 Nucleoside phosphorylase; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 4249124..4249822 Escherichia coli O104:H4 str. 2009EL-2050 13691560 YP_006771755.1 CDS O3M_20670 NC_018650.1 4249815 4250615 D COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; vitamin B12-transporter protein BtuF 4249815..4250615 Escherichia coli O104:H4 str. 2009EL-2050 13691561 YP_006771756.1 CDS O3M_20675 NC_018650.1 4250653 4251276 D COG2860 Predicted membrane protein; hypothetical protein 4250653..4251276 Escherichia coli O104:H4 str. 2009EL-2050 13691562 YP_006771757.1 CDS O3M_20680 NC_018650.1 4251323 4251667 R COG0316 Uncharacterized conserved protein; iron-sulfur cluster insertion protein ErpA complement(4251323..4251667) Escherichia coli O104:H4 str. 2009EL-2050 13691563 YP_006771758.1 CDS O3M_20685 NC_018650.1 4251749 4253170 R COG0038 Chloride channel protein EriC; chloride channel protein complement(4251749..4253170) Escherichia coli O104:H4 str. 2009EL-2050 13691564 YP_006771759.1 CDS O3M_20690 NC_018650.1 4253395 4254675 D COG0001 Glutamate-1-semialdehyde aminotransferase; glutamate-1-semialdehyde aminotransferase 4253395..4254675 Escherichia coli O104:H4 str. 2009EL-2050 13691565 YP_006771760.1 CDS O3M_20695 NC_018650.1 4254710 4256692 R COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-hydroxamate transporter permease subunit complement(4254710..4256692) Escherichia coli O104:H4 str. 2009EL-2050 13691566 YP_006771761.1 CDS O3M_20700 NC_018650.1 4256689 4257579 R COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; iron-hydroxamate transporter substrate-binding subunit complement(4256689..4257579) Escherichia coli O104:H4 str. 2009EL-2050 13691567 YP_006771762.1 CDS O3M_20705 NC_018650.1 4257579 4258376 R COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-hydroxamate transporter ATP-binding subunit complement(4257579..4258376) Escherichia coli O104:H4 str. 2009EL-2050 13691568 YP_006771763.1 CDS O3M_20710 NC_018650.1 4258427 4260670 R COG1629 Outer membrane receptor proteins, mostly Fe transport; ferrichrome outer membrane transporter complement(4258427..4260670) Escherichia coli O104:H4 str. 2009EL-2050 13691569 YP_006771764.1 CDS mrcB NC_018650.1 4260890 4263424 R COG0744 Membrane carboxypeptidase (penicillin-binding protein); bifunctional glycosyl transferase/transpeptidase complement(4260890..4263424) Escherichia coli O104:H4 str. 2009EL-2050 13691570 YP_006771765.1 CDS O3M_20720 NC_018650.1 4263411 4263617 R hypothetical protein complement(4263411..4263617) Escherichia coli O104:H4 str. 2009EL-2050 13691571 YP_006771766.1 CDS O3M_20725 NC_018650.1 4263620 4266049 R COG1643 HrpA-like helicases; ATP-dependent RNA helicase HrpB complement(4263620..4266049) Escherichia coli O104:H4 str. 2009EL-2050 13691572 YP_006771767.1 CDS O3M_20730 NC_018650.1 4266123 4266653 D COG1514 2'-5' RNA ligase; 2'-5' RNA ligase 4266123..4266653 Escherichia coli O104:H4 str. 2009EL-2050 13691573 YP_006771768.1 CDS O3M_20735 NC_018650.1 4266668 4267372 D COG1489 DNA-binding protein, stimulates sugar fermentation; DNA-binding transcriptional regulator 4266668..4267372 Escherichia coli O104:H4 str. 2009EL-2050 13691574 YP_006771769.1 CDS dksA NC_018650.1 4267550 4268005 D COG1734 DnaK suppressor protein; RNA polymerase-binding transcription factor 4267550..4268005 Escherichia coli O104:H4 str. 2009EL-2050 13691575 YP_006771770.1 CDS O3M_20745 NC_018650.1 4268042 4268968 D COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-Q tRNA(Asp) synthetase 4268042..4268968 Escherichia coli O104:H4 str. 2009EL-2050 13691576 YP_006771771.1 CDS pcnB NC_018650.1 4269007 4270425 D COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; poly(A) polymerase I 4269007..4270425 Escherichia coli O104:H4 str. 2009EL-2050 13691577 YP_006771772.1 CDS O3M_20755 NC_018650.1 4270422 4270901 D COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 4270422..4270901 Escherichia coli O104:H4 str. 2009EL-2050 13691578 YP_006771773.1 CDS O3M_20760 NC_018650.1 4271271 4271855 D COG3539 P pilus assembly protein, pilin FimA; fimbrial-like protein 4271271..4271855 Escherichia coli O104:H4 str. 2009EL-2050 13691579 YP_006771774.1 CDS O3M_20765 NC_018650.1 4271960 4272700 D COG3121 P pilus assembly protein, chaperone PapD; chaperone protein EcpD 4271960..4272700 Escherichia coli O104:H4 str. 2009EL-2050 13691580 YP_006771775.1 CDS O3M_20770 NC_018650.1 4272735 4275335 D COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 4272735..4275335 Escherichia coli O104:H4 str. 2009EL-2050 13691581 YP_006771776.1 CDS O3M_20775 NC_018650.1 4275352 4275921 D fimbrial protein 4275352..4275921 Escherichia coli O104:H4 str. 2009EL-2050 13691582 YP_006771777.1 CDS O3M_20780 NC_018650.1 4275936 4276538 D fimbrial protein StaE 4275936..4276538 Escherichia coli O104:H4 str. 2009EL-2050 13691583 YP_006771778.1 CDS O3M_20785 NC_018650.1 4276565 4277161 D fimbrial protein StaF 4276565..4277161 Escherichia coli O104:H4 str. 2009EL-2050 13691584 YP_006771779.1 CDS O3M_20790 NC_018650.1 4277214 4278488 D fimbrial-like adhesin protein 4277214..4278488 Escherichia coli O104:H4 str. 2009EL-2050 13691585 YP_006771780.1 CDS panB NC_018650.1 4278601 4279395 D COG0413 Ketopantoate hydroxymethyltransferase; 3-methyl-2-oxobutanoate hydroxymethyltransferase 4278601..4279395 Escherichia coli O104:H4 str. 2009EL-2050 13691586 YP_006771781.1 CDS panC NC_018650.1 4279407 4280258 D COG0414 Panthothenate synthetase; pantoate--beta-alanine ligase 4279407..4280258 Escherichia coli O104:H4 str. 2009EL-2050 13691587 YP_006771782.1 CDS O3M_20805 NC_018650.1 4280332 4281234 R transposase complement(4280332..4281234) Escherichia coli O104:H4 str. 2009EL-2050 13691588 YP_006771783.1 CDS O3M_20810 NC_018650.1 4281508 4281888 D COG0853 Aspartate 1-decarboxylase; aspartate alpha-decarboxylase 4281508..4281888 Escherichia coli O104:H4 str. 2009EL-2050 13691589 YP_006771784.1 CDS O3M_20815 NC_018650.1 4281892 4283121 R COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase complement(4281892..4283121) Escherichia coli O104:H4 str. 2009EL-2050 13691590 YP_006771785.1 CDS O3M_20820 NC_018650.1 4283185 4283625 R COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system transporter subunit IIA complement(4283185..4283625) Escherichia coli O104:H4 str. 2009EL-2050 13691591 YP_006771786.1 CDS O3M_20825 NC_018650.1 4283730 4284500 R COG0842 ABC-type multidrug transport system, permease component; inner membrane transport permease complement(4283730..4284500) Escherichia coli O104:H4 str. 2009EL-2050 13691592 YP_006771787.1 CDS O3M_20830 NC_018650.1 4284497 4285423 R COG1131 ABC-type multidrug transport system, ATPase component; transporter subunit complement(4284497..4285423) Escherichia coli O104:H4 str. 2009EL-2050 13691593 YP_006771788.1 CDS O3M_20835 NC_018650.1 4285532 4286194 D COG0288 Carbonic anhydrase; carbonic anhydrase 4285532..4286194 Escherichia coli O104:H4 str. 2009EL-2050 13691594 YP_006771789.1 CDS O3M_20840 NC_018650.1 4286235 4286771 R COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase complement(4286235..4286771) Escherichia coli O104:H4 str. 2009EL-2050 13691676 YP_006771790.1 CDS O3M_20845 NC_018650.1 4286977 4289367 D COG4993 Glucose dehydrogenase; glucose dehydrogenase 4286977..4289367 Escherichia coli O104:H4 str. 2009EL-2050 13691677 YP_006771791.1 CDS O3M_20850 NC_018650.1 4289414 4290964 R COG2132 Putative multicopper oxidases; multicopper oxidase complement(4289414..4290964) Escherichia coli O104:H4 str. 2009EL-2050 13691678 YP_006771792.1 CDS O3M_20855 NC_018650.1 4291130 4291477 D hypothetical protein 4291130..4291477 Escherichia coli O104:H4 str. 2009EL-2050 13691679 YP_006771793.1 CDS O3M_20860 NC_018650.1 4291583 4292449 D COG0421 Spermidine synthase; spermidine synthase 4291583..4292449 Escherichia coli O104:H4 str. 2009EL-2050 13691680 YP_006771794.1 CDS O3M_20865 NC_018650.1 4292465 4293259 D COG1586 S-adenosylmethionine decarboxylase; S-adenosylmethionine decarboxylase 4292465..4293259 Escherichia coli O104:H4 str. 2009EL-2050 13691681 YP_006771795.1 CDS O3M_20870 NC_018650.1 4293297 4293659 R COG3112 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4293297..4293659) Escherichia coli O104:H4 str. 2009EL-2050 13691682 YP_006771796.1 CDS O3M_20875 NC_018650.1 4293835 4296432 R COG1049 Aconitase B; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase complement(4293835..4296432) Escherichia coli O104:H4 str. 2009EL-2050 13691683 YP_006771797.1 CDS O3M_20880 NC_018650.1 4296787 4298544 D hypothetical protein 4296787..4298544 Escherichia coli O104:H4 str. 2009EL-2050 13691684 YP_006771798.1 CDS O3M_20885 NC_018650.1 4298615 4300039 R COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; dihydrolipoamide dehydrogenase complement(4298615..4300039) Escherichia coli O104:H4 str. 2009EL-2050 13691685 YP_006771799.1 CDS aceF NC_018650.1 4300364 4302256 R COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; pyruvate dehydrogenase dihydrolipoyltransacetylase complement(4300364..4302256) Escherichia coli O104:H4 str. 2009EL-2050 13691686 YP_006771800.1 CDS aceE NC_018650.1 4302271 4304934 R COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component; pyruvate dehydrogenase subunit E1 complement(4302271..4304934) Escherichia coli O104:H4 str. 2009EL-2050 13691687 YP_006771801.1 CDS pdhR NC_018650.1 4305095 4305859 R COG2186 Transcriptional regulators; transcriptional regulator PdhR complement(4305095..4305859) Escherichia coli O104:H4 str. 2009EL-2050 13691688 YP_006771802.1 CDS O3M_20905 NC_018650.1 4306403 4307773 D COG1113 Gamma-aminobutyrate permease and related permeases; aromatic amino acid transporter 4306403..4307773 Escherichia coli O104:H4 str. 2009EL-2050 13691689 YP_006771803.1 CDS O3M_20910 NC_018650.1 4307816 4308670 R COG1270 Cobalamin biosynthesis protein CobD/CbiB; regulatory protein AmpE complement(4307816..4308670) Escherichia coli O104:H4 str. 2009EL-2050 13691690 YP_006771804.1 CDS O3M_20915 NC_018650.1 4308667 4309218 R COG3023 Negative regulator of beta-lactamase expression; N-acetyl-anhydromuranmyl-L-alanine amidase complement(4308667..4309218) Escherichia coli O104:H4 str. 2009EL-2050 13691691 YP_006771805.1 CDS O3M_20920 NC_018650.1 4309306 4310199 D COG0157 Nicotinate-nucleotide pyrophosphorylase; quinolinate phosphoribosyltransferase 4309306..4310199 Escherichia coli O104:H4 str. 2009EL-2050 13691692 YP_006771806.1 CDS O3M_20925 NC_018650.1 4310402 4310842 D COG4969 Tfp pilus assembly protein, major pilin PilA; major pilin subunit 4310402..4310842 Escherichia coli O104:H4 str. 2009EL-2050 13691693 YP_006771807.1 CDS O3M_20930 NC_018650.1 4310852 4312237 D COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; hypothetical protein 4310852..4312237 Escherichia coli O104:H4 str. 2009EL-2050 13691694 YP_006771808.1 CDS O3M_20935 NC_018650.1 4312227 4313429 D COG1459 Type II secretory pathway, component PulF; type IV pilin biogenesis protein 4312227..4313429 Escherichia coli O104:H4 str. 2009EL-2050 13691695 YP_006771809.1 CDS O3M_20940 NC_018650.1 4313464 4314507 R COG0516 IMP dehydrogenase/GMP reductase; guanosine 5'-monophosphate oxidoreductase complement(4313464..4314507) Escherichia coli O104:H4 str. 2009EL-2050 13691696 YP_006771810.1 CDS coaE NC_018650.1 4314732 4315352 D COG0237 Dephospho-CoA kinase; dephospho-CoA kinase 4314732..4315352 Escherichia coli O104:H4 str. 2009EL-2050 13691697 YP_006771811.1 CDS O3M_20950 NC_018650.1 4315352 4316095 D COG4582 Uncharacterized protein conserved in bacteria; hypothetical protein 4315352..4316095 Escherichia coli O104:H4 str. 2009EL-2050 13691698 YP_006771812.1 CDS O3M_20955 NC_018650.1 4316105 4316302 D COG3024 Uncharacterized protein conserved in bacteria; DNA gyrase inhibitor 4316105..4316302 Escherichia coli O104:H4 str. 2009EL-2050 13691699 YP_006771813.1 CDS O3M_20960 NC_018650.1 4316402 4316791 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; nucleoside triphosphate pyrophosphohydrolase complement(4316402..4316791) Escherichia coli O104:H4 str. 2009EL-2050 13691700 YP_006771814.1 CDS O3M_20965 NC_018650.1 4316851 4319556 R COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); preprotein translocase subunit SecA complement(4316851..4319556) Escherichia coli O104:H4 str. 2009EL-2050 13691701 YP_006771815.1 CDS O3M_20970 NC_018650.1 4319618 4320130 R SecA regulator SecM complement(4319618..4320130) Escherichia coli O104:H4 str. 2009EL-2050 13691702 YP_006771816.1 CDS lpxC NC_018650.1 4320361 4321278 R COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(4320361..4321278) Escherichia coli O104:H4 str. 2009EL-2050 13691703 YP_006771817.1 CDS O3M_20980 NC_018650.1 4321379 4322530 R COG0206 Cell division GTPase; cell division protein FtsZ complement(4321379..4322530) Escherichia coli O104:H4 str. 2009EL-2050 13691704 YP_006771818.1 CDS ftsA NC_018650.1 4322591 4323853 R COG0849 Actin-like ATPase involved in cell division; cell division protein FtsA complement(4322591..4323853) Escherichia coli O104:H4 str. 2009EL-2050 13691705 YP_006771819.1 CDS O3M_20990 NC_018650.1 4323850 4324680 R COG1589 Cell division septal protein; cell division protein FtsQ complement(4323850..4324680) Escherichia coli O104:H4 str. 2009EL-2050 13691706 YP_006771820.1 CDS ddl NC_018650.1 4324682 4325602 R D-alanine-D-alanine ligase A; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanyl-alanine synthetase A complement(4324682..4325602) Escherichia coli O104:H4 str. 2009EL-2050 13691707 YP_006771821.1 CDS murC NC_018650.1 4325595 4327070 R COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate--L-alanine ligase complement(4325595..4327070) Escherichia coli O104:H4 str. 2009EL-2050 13691708 YP_006771822.1 CDS murG NC_018650.1 4327124 4328191 R COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase complement(4327124..4328191) Escherichia coli O104:H4 str. 2009EL-2050 13691709 YP_006771823.1 CDS O3M_21010 NC_018650.1 4328188 4329432 R COG0772 Bacterial cell division membrane protein; cell division protein FtsW complement(4328188..4329432) Escherichia coli O104:H4 str. 2009EL-2050 13691710 YP_006771824.1 CDS murD NC_018650.1 4329432 4330748 R COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(4329432..4330748) Escherichia coli O104:H4 str. 2009EL-2050 13691711 YP_006771825.1 CDS mraY NC_018650.1 4330751 4331833 R COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(4330751..4331833) Escherichia coli O104:H4 str. 2009EL-2050 13691712 YP_006771826.1 CDS murF NC_018650.1 4331827 4333185 R COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(4331827..4333185) Escherichia coli O104:H4 str. 2009EL-2050 13691713 YP_006771827.1 CDS murE NC_018650.1 4333182 4334669 R COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(4333182..4334669) Escherichia coli O104:H4 str. 2009EL-2050 13691714 YP_006771828.1 CDS O3M_21035 NC_018650.1 4334656 4336422 R COG0768 Cell division protein FtsI/penicillin-binding protein 2; peptidoglycan synthase FtsI complement(4334656..4336422) Escherichia coli O104:H4 str. 2009EL-2050 13691715 YP_006771829.1 CDS O3M_21040 NC_018650.1 4336438 4336803 R COG3116 Cell division protein; cell division protein FtsL complement(4336438..4336803) Escherichia coli O104:H4 str. 2009EL-2050 13691716 YP_006771830.1 CDS O3M_21045 NC_018650.1 4336800 4337741 R COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; 16S rRNA m(4)C1402 methyltransferase complement(4336800..4337741) Escherichia coli O104:H4 str. 2009EL-2050 13691717 YP_006771831.1 CDS O3M_21050 NC_018650.1 4337743 4338201 R COG2001 Uncharacterized protein conserved in bacteria; cell division protein MraZ complement(4337743..4338201) Escherichia coli O104:H4 str. 2009EL-2050 13691718 YP_006771832.1 CDS O3M_21055 NC_018650.1 4338803 4339807 R COG1609 Transcriptional regulators; DNA-binding transcriptional regulator FruR complement(4338803..4339807) Escherichia coli O104:H4 str. 2009EL-2050 13691719 YP_006771833.1 CDS ilvH NC_018650.1 4339987 4340478 R COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase 3 regulatory subunit complement(4339987..4340478) Escherichia coli O104:H4 str. 2009EL-2050 13691720 YP_006771834.1 CDS O3M_21065 NC_018650.1 4340481 4342205 R COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase 3 catalytic subunit complement(4340481..4342205) Escherichia coli O104:H4 str. 2009EL-2050 13691721 YP_006771835.1 CDS leuO NC_018650.1 4342523 4343467 R COG0583 Transcriptional regulator; leucine transcriptional activator complement(4342523..4343467) Escherichia coli O104:H4 str. 2009EL-2050 13691722 YP_006771836.1 CDS O3M_21075 NC_018650.1 4344128 4344214 D leu operon leader peptide 4344128..4344214 Escherichia coli O104:H4 str. 2009EL-2050 13691723 YP_006771837.1 CDS O3M_21080 NC_018650.1 4344307 4345878 D COG0119 Isopropylmalate/homocitrate/citramalate synthases; 2-isopropylmalate synthase 4344307..4345878 Escherichia coli O104:H4 str. 2009EL-2050 13691724 YP_006771838.1 CDS O3M_21085 NC_018650.1 4345878 4346969 D COG0473 Isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 4345878..4346969 Escherichia coli O104:H4 str. 2009EL-2050 13691725 YP_006771839.1 CDS O3M_21090 NC_018650.1 4346972 4348372 D COG0065 3-isopropylmalate dehydratase large subunit; isopropylmalate isomerase large subunit 4346972..4348372 Escherichia coli O104:H4 str. 2009EL-2050 13691726 YP_006771840.1 CDS leuD NC_018650.1 4348383 4348988 D COG0066 3-isopropylmalate dehydratase small subunit; isopropylmalate isomerase small subunit 4348383..4348988 Escherichia coli O104:H4 str. 2009EL-2050 13691727 YP_006771841.1 CDS O3M_21100 NC_018650.1 4349037 4350215 R COG0477 Permeases of the major facilitator superfamily; broad specificity sugar efflux system SetA complement(4349037..4350215) Escherichia coli O104:H4 str. 2009EL-2050 13691728 YP_006771842.1 CDS O3M_21105 NC_018650.1 4350317 4350448 R hypothetical protein complement(4350317..4350448) Escherichia coli O104:H4 str. 2009EL-2050 13691729 YP_006771843.1 CDS O3M_21110 NC_018650.1 4350537 4352192 D COG4533 ABC-type uncharacterized transport system, periplasmic component; transcriptional regulator SgrR 4350537..4352192 Escherichia coli O104:H4 str. 2009EL-2050 13691730 YP_006771844.1 CDS tbpA NC_018650.1 4352356 4353339 D COG4143 ABC-type thiamine transport system, periplasmic component; thiamine transporter substrate binding subunit 4352356..4353339 Escherichia coli O104:H4 str. 2009EL-2050 13691731 YP_006771845.1 CDS thiP NC_018650.1 4353315 4354925 D COG0555 ABC-type sulfate transport system, permease component; thiamine transporter membrane protein 4353315..4354925 Escherichia coli O104:H4 str. 2009EL-2050 13691732 YP_006771846.1 CDS thiQ NC_018650.1 4354909 4355607 D COG3840 ABC-type thiamine transport system, ATPase component; thiamine transporter ATP-binding subunit 4354909..4355607 Escherichia coli O104:H4 str. 2009EL-2050 13691733 YP_006771847.1 CDS O3M_21130 NC_018650.1 4355721 4356485 R COG0586 Uncharacterized membrane-associated protein; hypothetical protein complement(4355721..4356485) Escherichia coli O104:H4 str. 2009EL-2050 13691734 YP_006771848.1 CDS O3M_21135 NC_018650.1 4356571 4357449 R COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator AraC complement(4356571..4357449) Escherichia coli O104:H4 str. 2009EL-2050 13691735 YP_006771849.1 CDS O3M_21140 NC_018650.1 4357788 4359488 D COG1069 Ribulose kinase; ribulokinase 4357788..4359488 Escherichia coli O104:H4 str. 2009EL-2050 13691736 YP_006771850.1 CDS O3M_21145 NC_018650.1 4359499 4361001 D COG2160 L-arabinose isomerase; L-arabinose isomerase 4359499..4361001 Escherichia coli O104:H4 str. 2009EL-2050 13691737 YP_006771851.1 CDS araD NC_018650.1 4361170 4361865 D COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase 4361170..4361865 Escherichia coli O104:H4 str. 2009EL-2050 13691738 YP_006771852.1 CDS O3M_21155 NC_018650.1 4361940 4364291 D COG0417 DNA polymerase elongation subunit (family B); DNA polymerase II 4361940..4364291 Escherichia coli O104:H4 str. 2009EL-2050 13691739 YP_006771853.1 CDS O3M_21160 NC_018650.1 4364456 4367362 D COG0553 Superfamily II DNA/RNA helicases, SNF2 family; ATP-dependent helicase HepA 4364456..4367362 Escherichia coli O104:H4 str. 2009EL-2050 13691740 YP_006771854.1 CDS O3M_21165 NC_018650.1 4367374 4368033 D COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA/tRNA pseudouridine synthase A 4367374..4368033 Escherichia coli O104:H4 str. 2009EL-2050 13691741 YP_006771855.1 CDS djlA NC_018650.1 4368150 4368965 R COG1076 DnaJ-domain-containing proteins 1; Dna-J like membrane chaperone protein complement(4368150..4368965) Escherichia coli O104:H4 str. 2009EL-2050 13691742 YP_006771856.1 CDS O3M_21175 NC_018650.1 4369220 4371574 D COG1452 Organic solvent tolerance protein OstA; LPS assembly outer membrane complex protein LptD 4369220..4371574 Escherichia coli O104:H4 str. 2009EL-2050 13691743 YP_006771857.1 CDS O3M_21180 NC_018650.1 4371627 4372913 D COG0760 Parvulin-like peptidyl-prolyl isomerase; peptidyl-prolyl cis-trans isomerase SurA 4371627..4372913 Escherichia coli O104:H4 str. 2009EL-2050 13691744 YP_006771858.1 CDS pdxA NC_018650.1 4372913 4373902 D COG1995 Pyridoxal phosphate biosynthesis protein; 4-hydroxythreonine-4-phosphate dehydrogenase 4372913..4373902 Escherichia coli O104:H4 str. 2009EL-2050 13691745 YP_006771859.1 CDS ksgA NC_018650.1 4373899 4374720 D COG0030 Dimethyladenosine transferase (rRNA methylation); KsgA/Dim1 family 16S ribosomal RNA methyltransferase 4373899..4374720 Escherichia coli O104:H4 str. 2009EL-2050 13691746 YP_006771860.1 CDS apaG NC_018650.1 4374723 4375100 D COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport; CO2+/MG2+ efflux protein ApaG 4374723..4375100 Escherichia coli O104:H4 str. 2009EL-2050 13691747 YP_006771861.1 CDS apaH NC_018650.1 4375107 4375949 D COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase 4375107..4375949 Escherichia coli O104:H4 str. 2009EL-2050 13691748 YP_006771862.1 CDS folA NC_018650.1 4376027 4376506 R COG0262 Dihydrofolate reductase; dihydrofolate reductase complement(4376027..4376506) Escherichia coli O104:H4 str. 2009EL-2050 13691749 YP_006771863.1 CDS O3M_21210 NC_018650.1 4376698 4378560 R COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefC complement(4376698..4378560) Escherichia coli O104:H4 str. 2009EL-2050 13691750 YP_006771864.1 CDS O3M_21215 NC_018650.1 4378553 4379083 R COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); glutathione-regulated potassium-efflux system ancillary protein KefF complement(4378553..4379083) Escherichia coli O104:H4 str. 2009EL-2050 13691751 YP_006771865.1 CDS O3M_21220 NC_018650.1 4379191 4380522 R COG0477 Permeases of the major facilitator superfamily; transporter complement(4379191..4380522) Escherichia coli O104:H4 str. 2009EL-2050 13691752 YP_006771866.1 CDS O3M_21225 NC_018650.1 4380581 4380868 R COG2440 Ferredoxin-like protein; ferredoxin-like protein FixX complement(4380581..4380868) Escherichia coli O104:H4 str. 2009EL-2050 13691753 YP_006771867.1 CDS O3M_21230 NC_018650.1 4380865 4382151 R COG0644 Dehydrogenases (flavoproteins); oxidoreductase FixC complement(4380865..4382151) Escherichia coli O104:H4 str. 2009EL-2050 13691754 YP_006771868.1 CDS fixB NC_018650.1 4382202 4383143 R COG2025 Electron transfer flavoprotein, alpha subunit; electron transfer flavoprotein FixB complement(4382202..4383143) Escherichia coli O104:H4 str. 2009EL-2050 13691755 YP_006771869.1 CDS O3M_21240 NC_018650.1 4383158 4383928 R COG2086 Electron transfer flavoprotein, beta subunit; electron transfer flavoprotein FixA complement(4383158..4383928) Escherichia coli O104:H4 str. 2009EL-2050 13691756 YP_006771870.1 CDS O3M_21245 NC_018650.1 4384402 4385916 D COG1292 Choline-glycine betaine transporter; L-carnitine/gamma-butyrobetaine antiporter 4384402..4385916 Escherichia coli O104:H4 str. 2009EL-2050 13691838 YP_006771871.1 CDS O3M_21250 NC_018650.1 4385947 4387089 D COG1960 Acyl-CoA dehydrogenases; crotonobetainyl-CoA dehydrogenase 4385947..4387089 Escherichia coli O104:H4 str. 2009EL-2050 13691839 YP_006771872.1 CDS O3M_21255 NC_018650.1 4387218 4388435 D COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; crotonobetainyl-CoA:carnitine CoA-transferase 4387218..4388435 Escherichia coli O104:H4 str. 2009EL-2050 13691840 YP_006771873.1 CDS caiC NC_018650.1 4388509 4390062 D COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; crotonobetaine/carnitine-CoA ligase 4388509..4390062 Escherichia coli O104:H4 str. 2009EL-2050 13691841 YP_006771874.1 CDS O3M_21265 NC_018650.1 4390171 4390956 D COG1024 Enoyl-CoA hydratase/carnithine racemase; carnitinyl-CoA dehydratase 4390171..4390956 Escherichia coli O104:H4 str. 2009EL-2050 13691842 YP_006771875.1 CDS O3M_21270 NC_018650.1 4390962 4391552 D COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; carnitine operon protein CaiE 4390962..4391552 Escherichia coli O104:H4 str. 2009EL-2050 13691843 YP_006771876.1 CDS O3M_21275 NC_018650.1 4391638 4392033 R DNA-binding transcriptional activator CaiF complement(4391638..4392033) Escherichia coli O104:H4 str. 2009EL-2050 13691844 YP_006771877.1 CDS carB NC_018650.1 4392294 4395515 R COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); carbamoyl phosphate synthase large subunit complement(4392294..4395515) Escherichia coli O104:H4 str. 2009EL-2050 13691845 YP_006771878.1 CDS O3M_21285 NC_018650.1 4395533 4396681 R COG0505 Carbamoylphosphate synthase small subunit; carbamoyl phosphate synthase small subunit complement(4395533..4396681) Escherichia coli O104:H4 str. 2009EL-2050 13691846 YP_006771879.1 CDS O3M_21290 NC_018650.1 4396799 4396894 D hypothetical protein 4396799..4396894 Escherichia coli O104:H4 str. 2009EL-2050 13691847 YP_006771880.1 CDS O3M_21295 NC_018650.1 4397137 4397958 R COG0289 Dihydrodipicolinate reductase; dihydrodipicolinate reductase complement(4397137..4397958) Escherichia coli O104:H4 str. 2009EL-2050 13691848 YP_006771881.1 CDS O3M_21300 NC_018650.1 4398125 4399039 R COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase RihC complement(4398125..4399039) Escherichia coli O104:H4 str. 2009EL-2050 13691849 YP_006771882.1 CDS ispH NC_018650.1 4399105 4400055 R COG0761 Penicillin tolerance protein; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(4399105..4400055) Escherichia coli O104:H4 str. 2009EL-2050 13691850 YP_006771883.1 CDS O3M_21310 NC_018650.1 4400057 4400506 R COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; FKBP-type peptidyl-prolyl cis-trans isomerase complement(4400057..4400506) Escherichia coli O104:H4 str. 2009EL-2050 13691851 YP_006771884.1 CDS lspA NC_018650.1 4400594 4401088 R COG0597 Lipoprotein signal peptidase; lipoprotein signal peptidase complement(4400594..4401088) Escherichia coli O104:H4 str. 2009EL-2050 13691852 YP_006771885.1 CDS ileS NC_018650.1 4401088 4403904 R COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase complement(4401088..4403904) Escherichia coli O104:H4 str. 2009EL-2050 13691853 YP_006771886.1 CDS O3M_21325 NC_018650.1 4403947 4404888 R COG0196 FAD synthase; bifunctional riboflavin kinase/FMN adenylyltransferase complement(4403947..4404888) Escherichia coli O104:H4 str. 2009EL-2050 13691854 YP_006771887.1 CDS O3M_21330 NC_018650.1 4404896 4405114 R hypothetical protein complement(4404896..4405114) Escherichia coli O104:H4 str. 2009EL-2050 13691855 YP_006771888.1 CDS rpsT NC_018650.1 4405217 4405480 D COG0268 Ribosomal protein S20; 30S ribosomal protein S20 4405217..4405480 Escherichia coli O104:H4 str. 2009EL-2050 13691856 YP_006771889.1 CDS O3M_21340 NC_018650.1 4406263 4407384 D COG1357 Uncharacterized low-complexity proteins; T3SS effector EspX 4406263..4407384 Escherichia coli O104:H4 str. 2009EL-2050 13691857 YP_006771890.1 CDS O3M_21345 NC_018650.1 4407817 4408962 D COG3188 P pilus assembly protein, porin PapC; hypothetical protein 4407817..4408962 Escherichia coli O104:H4 str. 2009EL-2050 13691858 YP_006771891.1 CDS O3M_21350 NC_018650.1 4408975 4409934 D hypothetical protein 4408975..4409934 Escherichia coli O104:H4 str. 2009EL-2050 13691859 YP_006771892.1 CDS nhaR NC_018650.1 4409973 4410878 R COG0583 Transcriptional regulator; transcriptional activator NhaR complement(4409973..4410878) Escherichia coli O104:H4 str. 2009EL-2050 13691860 YP_006771893.1 CDS nhaA NC_018650.1 4410938 4412104 R COG3004 Na+/H+ antiporter; pH-dependent sodium/proton antiporter complement(4410938..4412104) Escherichia coli O104:H4 str. 2009EL-2050 13691861 YP_006771894.1 CDS O3M_21365 NC_018650.1 4412633 4412842 D regulatory protein MokC for HokC 4412633..4412842 Escherichia coli O104:H4 str. 2009EL-2050 13691862 YP_006771895.1 CDS O3M_21370 NC_018650.1 4412946 4414076 R COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; chaperone protein DnaJ complement(4412946..4414076) Escherichia coli O104:H4 str. 2009EL-2050 13691863 YP_006771896.1 CDS dnaK NC_018650.1 4414165 4416081 R COG0443 Molecular chaperone; molecular chaperone DnaK complement(4414165..4416081) Escherichia coli O104:H4 str. 2009EL-2050 13691864 YP_006771897.1 CDS O3M_21380 NC_018650.1 4416458 4416862 D hypothetical protein 4416458..4416862 Escherichia coli O104:H4 str. 2009EL-2050 13691865 YP_006771898.1 CDS O3M_21385 NC_018650.1 4416888 4417601 D COG4735 Uncharacterized protein conserved in bacteria; hypothetical protein 4416888..4417601 Escherichia coli O104:H4 str. 2009EL-2050 13691866 YP_006771899.1 CDS O3M_21390 NC_018650.1 4417750 4418316 D COG1584 Predicted membrane protein; hypothetical protein 4417750..4418316 Escherichia coli O104:H4 str. 2009EL-2050 13691867 YP_006771900.1 CDS mogA NC_018650.1 4418351 4418938 R COG0521 Molybdopterin biosynthesis enzymes; molybdenum cofactor biosynthesis protein MogA complement(4418351..4418938) Escherichia coli O104:H4 str. 2009EL-2050 13691868 YP_006771901.1 CDS O3M_21400 NC_018650.1 4419053 4420006 R COG0176 Transaldolase; transaldolase B complement(4419053..4420006) Escherichia coli O104:H4 str. 2009EL-2050 13691869 YP_006771902.1 CDS O3M_21405 NC_018650.1 4420285 4421715 D COG1115 Na+/alanine symporter; transporter 4420285..4421715 Escherichia coli O104:H4 str. 2009EL-2050 13691870 YP_006771903.1 CDS O3M_21410 NC_018650.1 4421785 4422561 D COG3022 Uncharacterized protein conserved in bacteria; hypothetical protein 4421785..4422561 Escherichia coli O104:H4 str. 2009EL-2050 13691871 YP_006771904.1 CDS O3M_21415 NC_018650.1 4422715 4423011 R hypothetical protein complement(4422715..4423011) Escherichia coli O104:H4 str. 2009EL-2050 13691872 YP_006771905.1 CDS O3M_21420 NC_018650.1 4423225 4424511 R COG0498 Threonine synthase; threonine synthase complement(4423225..4424511) Escherichia coli O104:H4 str. 2009EL-2050 13691873 YP_006771906.1 CDS O3M_21425 NC_018650.1 4424512 4425444 R COG0083 Homoserine kinase; homoserine kinase complement(4424512..4425444) Escherichia coli O104:H4 str. 2009EL-2050 13691874 YP_006771907.1 CDS thrA NC_018650.1 4425446 4427908 R COG0527 Aspartokinases; bifunctional aspartokinase I/homoserine dehydrogenase I complement(4425446..4427908) Escherichia coli O104:H4 str. 2009EL-2050 13691875 YP_006771908.1 CDS O3M_21435 NC_018650.1 4428268 4428954 R COG0565 rRNA methylase; RNA methyltransferase complement(4428268..4428954) Escherichia coli O104:H4 str. 2009EL-2050 13691876 YP_006771909.1 CDS O3M_21440 NC_018650.1 4429590 4430306 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component response regulator 4429590..4430306 Escherichia coli O104:H4 str. 2009EL-2050 13691877 YP_006771910.1 CDS O3M_21445 NC_018650.1 4430366 4431718 R COG4452 Inner membrane protein involved in colicin E2 resistance; inner membrane protein complement(4430366..4431718) Escherichia coli O104:H4 str. 2009EL-2050 13691878 YP_006771911.1 CDS O3M_21450 NC_018650.1 4431776 4433200 R COG0642 Signal transduction histidine kinase; sensory histidine kinase CreC complement(4431776..4433200) Escherichia coli O104:H4 str. 2009EL-2050 13691879 YP_006771912.1 CDS O3M_21455 NC_018650.1 4433200 4433889 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding response regulator CreB complement(4433200..4433889) Escherichia coli O104:H4 str. 2009EL-2050 13691880 YP_006771913.1 CDS O3M_21460 NC_018650.1 4433902 4434375 R COG3045 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4433902..4434375) Escherichia coli O104:H4 str. 2009EL-2050 13691881 YP_006771914.1 CDS O3M_21465 NC_018650.1 4434586 4435455 D COG2207 AraC-type DNA-binding domain-containing proteins; right oriC-binding transcriptional activator 4434586..4435455 Escherichia coli O104:H4 str. 2009EL-2050 13691882 YP_006771915.1 CDS O3M_21470 NC_018650.1 4435452 4436099 R COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase complement(4435452..4436099) Escherichia coli O104:H4 str. 2009EL-2050 13691883 YP_006771916.1 CDS O3M_21475 NC_018650.1 4436151 4436663 D COG1986 Uncharacterized conserved protein; inosine/xanthosine triphosphatase 4436151..4436663 Escherichia coli O104:H4 str. 2009EL-2050 13691884 YP_006771917.1 CDS O3M_21480 NC_018650.1 4436705 4437031 R COG2973 Trp operon repressor; Trp operon repressor complement(4436705..4437031) Escherichia coli O104:H4 str. 2009EL-2050 13691885 YP_006771918.1 CDS O3M_21485 NC_018650.1 4437121 4439058 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic murein transglycosylase complement(4437121..4439058) Escherichia coli O104:H4 str. 2009EL-2050 13691886 YP_006771919.1 CDS O3M_21490 NC_018650.1 4439269 4440936 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 4439269..4440936 Escherichia coli O104:H4 str. 2009EL-2050 13691887 YP_006771920.1 CDS O3M_21495 NC_018650.1 4441243 4442475 R COG1396 Predicted transcriptional regulators; bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase complement(4441243..4442475) Escherichia coli O104:H4 str. 2009EL-2050 13691888 YP_006771921.1 CDS O3M_21500 NC_018650.1 4442496 4443878 R COG1066 Predicted ATP-dependent serine protease; DNA repair protein RadA complement(4442496..4443878) Escherichia coli O104:H4 str. 2009EL-2050 13691889 YP_006771922.1 CDS serB NC_018650.1 4443927 4444895 R COG0560 Phosphoserine phosphatase; phosphoserine phosphatase complement(4443927..4444895) Escherichia coli O104:H4 str. 2009EL-2050 13691890 YP_006771923.1 CDS O3M_21510 NC_018650.1 4445001 4445645 D COG3726 Uncharacterized membrane protein affecting hemolysin expression; hypothetical protein 4445001..4445645 Escherichia coli O104:H4 str. 2009EL-2050 13691891 YP_006771924.1 CDS lplA NC_018650.1 4445673 4446689 D COG0095 Lipoate-protein ligase A; lipoate-protein ligase A 4445673..4446689 Escherichia coli O104:H4 str. 2009EL-2050 13691892 YP_006771925.1 CDS O3M_21520 NC_018650.1 4446721 4446870 D hypothetical protein 4446721..4446870 Escherichia coli O104:H4 str. 2009EL-2050 13691893 YP_006771926.1 CDS deoD NC_018650.1 4447145 4447864 R COG0813 Purine-nucleoside phosphorylase; purine nucleoside phosphorylase complement(4447145..4447864) Escherichia coli O104:H4 str. 2009EL-2050 13691894 YP_006771927.1 CDS O3M_21530 NC_018650.1 4447944 4449167 R COG1015 Phosphopentomutase; phosphopentomutase complement(4447944..4449167) Escherichia coli O104:H4 str. 2009EL-2050 13691895 YP_006771928.1 CDS deoA NC_018650.1 4449219 4450541 R COG0213 Thymidine phosphorylase; thymidine phosphorylase complement(4449219..4450541) Escherichia coli O104:H4 str. 2009EL-2050 13691896 YP_006771929.1 CDS O3M_21540 NC_018650.1 4450619 4451398 R COG0274 Deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase complement(4450619..4451398) Escherichia coli O104:H4 str. 2009EL-2050 13691897 YP_006771930.1 CDS O3M_21545 NC_018650.1 4451656 4453206 D hypothetical protein 4451656..4453206 Escherichia coli O104:H4 str. 2009EL-2050 13691898 YP_006771931.1 CDS O3M_21550 NC_018650.1 4453178 4454041 D COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase activating enzyme 4453178..4454041 Escherichia coli O104:H4 str. 2009EL-2050 13691899 YP_006771932.1 CDS O3M_21555 NC_018650.1 4454271 4455053 R COG0084 Mg-dependent DNase; deoxyribonuclease YjjV complement(4454271..4455053) Escherichia coli O104:H4 str. 2009EL-2050 13691900 YP_006771933.1 CDS O3M_21560 NC_018650.1 4455050 4456123 R COG4667 Predicted esterase of the alpha-beta hydrolase superfamily; esterase complement(4455050..4456123) Escherichia coli O104:H4 str. 2009EL-2050 13691901 YP_006771934.1 CDS O3M_21565 NC_018650.1 4456245 4456406 R hypothetical protein complement(4456245..4456406) Escherichia coli O104:H4 str. 2009EL-2050 13691902 YP_006771935.1 CDS O3M_21570 NC_018650.1 4456533 4457138 R COG2823 Predicted periplasmic or secreted lipoprotein; hypothetical protein complement(4456533..4457138) Escherichia coli O104:H4 str. 2009EL-2050 13691903 YP_006771936.1 CDS prfC NC_018650.1 4457531 4459120 R COG4108 Peptide chain release factor RF-3; peptide chain release factor 3 complement(4457531..4459120) Escherichia coli O104:H4 str. 2009EL-2050 13691904 YP_006771937.1 CDS O3M_21580 NC_018650.1 4459211 4459888 R COG1011 Predicted hydrolase (HAD superfamily); dUMP phosphatase complement(4459211..4459888) Escherichia coli O104:H4 str. 2009EL-2050 13691905 YP_006771938.1 CDS rimI NC_018650.1 4459903 4460349 R COG0456 Acetyltransferases; ribosomal-protein-alanine N-acetyltransferase complement(4459903..4460349) Escherichia coli O104:H4 str. 2009EL-2050 13691906 YP_006771939.1 CDS O3M_21590 NC_018650.1 4460318 4460731 R COG3050 DNA polymerase III, psi subunit; DNA polymerase III subunit psi complement(4460318..4460731) Escherichia coli O104:H4 str. 2009EL-2050 13691907 YP_006771940.1 CDS rsmC NC_018650.1 4460834 4461865 D COG2813 16S RNA G1207 methylase RsmC; 16S ribosomal RNA m2G1207 methyltransferase 4460834..4461865 Escherichia coli O104:H4 str. 2009EL-2050 13691908 YP_006771941.1 CDS O3M_21600 NC_018650.1 4462535 4462771 R hypothetical protein complement(4462535..4462771) Escherichia coli O104:H4 str. 2009EL-2050 13691912 YP_006771942.1 CDS O3M_21605 NC_018650.1 4462912 4463700 D COG4114 Uncharacterized Fe-S protein; ferric hydroximate transport ferric iron reductase 4462912..4463700 Escherichia coli O104:H4 str. 2009EL-2050 13691913 YP_006771943.1 CDS O3M_21610 NC_018650.1 4463738 4464361 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator BglJ complement(4463738..4464361) Escherichia coli O104:H4 str. 2009EL-2050 13691914 YP_006771944.1 CDS O3M_21615 NC_018650.1 4464373 4465098 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional regulator complement(4464373..4465098) Escherichia coli O104:H4 str. 2009EL-2050 13691915 YP_006771945.1 CDS O3M_21620 NC_018650.1 4465719 4466489 D COG2966 Uncharacterized conserved protein; hypothetical protein 4465719..4466489 Escherichia coli O104:H4 str. 2009EL-2050 13691916 YP_006771946.1 CDS O3M_21625 NC_018650.1 4466480 4466953 D COG3610 Uncharacterized conserved protein; hypothetical protein 4466480..4466953 Escherichia coli O104:H4 str. 2009EL-2050 13691917 YP_006771947.1 CDS O3M_21630 NC_018650.1 4467060 4467599 D primosomal protein DnaI 4467060..4467599 Escherichia coli O104:H4 str. 2009EL-2050 13691918 YP_006771948.1 CDS O3M_21635 NC_018650.1 4467602 4468339 D COG1484 DNA replication protein; DNA replication protein DnaC 4467602..4468339 Escherichia coli O104:H4 str. 2009EL-2050 13691989 YP_006771949.1 CDS O3M_21640 NC_018650.1 4468385 4468882 D hypothetical protein 4468385..4468882 Escherichia coli O104:H4 str. 2009EL-2050 13691990 YP_006771950.1 CDS O3M_21645 NC_018650.1 4469136 4471427 D COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; phosphoglycerol transferase I 4469136..4471427 Escherichia coli O104:H4 str. 2009EL-2050 13691991 YP_006771951.1 CDS O3M_21650 NC_018650.1 4471568 4472590 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein complement(4471568..4472590) Escherichia coli O104:H4 str. 2009EL-2050 13691992 YP_006771952.1 CDS O3M_21655 NC_018650.1 4472729 4473643 D COG1802 Transcriptional regulators; GntR family transcriptional regulator 4472729..4473643 Escherichia coli O104:H4 str. 2009EL-2050 13691993 YP_006771953.1 CDS O3M_21660 NC_018650.1 4473858 4475219 D COG0477 Permeases of the major facilitator superfamily; transporter 4473858..4475219 Escherichia coli O104:H4 str. 2009EL-2050 13691994 YP_006771954.1 CDS O3M_21665 NC_018650.1 4475268 4476932 R COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein I complement(4475268..4476932) Escherichia coli O104:H4 str. 2009EL-2050 13691995 YP_006771955.1 CDS O3M_21670 NC_018650.1 4477309 4479459 D COG1966 Carbon starvation protein, predicted membrane protein; inner membrane protein 4477309..4479459 Escherichia coli O104:H4 str. 2009EL-2050 13691996 YP_006771956.1 CDS O3M_21675 NC_018650.1 4479590 4479793 D COG2879 Uncharacterized small protein; hypothetical protein 4479590..4479793 Escherichia coli O104:H4 str. 2009EL-2050 13691997 YP_006771957.1 CDS O3M_21680 NC_018650.1 4479804 4480760 D COG0523 Putative GTPases (G3E family); GTP-binding protein YjiA 4479804..4480760 Escherichia coli O104:H4 str. 2009EL-2050 13691998 YP_006771958.1 CDS O3M_21685 NC_018650.1 4480829 4482481 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(4480829..4482481) Escherichia coli O104:H4 str. 2009EL-2050 13691999 YP_006771959.1 CDS O3M_21690 NC_018650.1 4482759 4485191 D COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme EcoAI R protein (R.EcoAI) 4482759..4485191 Escherichia coli O104:H4 str. 2009EL-2050 13692000 YP_006771960.1 CDS O3M_21695 NC_018650.1 4485258 4486727 D COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme EcoEI M protein (M.EcoEI) 4485258..4486727 Escherichia coli O104:H4 str. 2009EL-2050 13692001 YP_006771961.1 CDS O3M_21700 NC_018650.1 4486727 4488463 D COG0732 Restriction endonuclease S subunits; type I restriction enzyme EcoAI specificity protein (S protein, S.EcoAI) 4486727..4488463 Escherichia coli O104:H4 str. 2009EL-2050 13692002 YP_006771962.1 CDS O3M_21705 NC_018650.1 4488684 4489025 D endoribonuclease SymE 4488684..4489025 Escherichia coli O104:H4 str. 2009EL-2050 13692003 YP_006771963.1 CDS O3M_21720 NC_018650.1 4491262 4491426 R hypothetical protein complement(4491262..4491426) Escherichia coli O104:H4 str. 2009EL-2050 13692004 YP_006771964.1 CDS O3M_21725 NC_018650.1 4491603 4493015 D aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; DNA-binding transcriptional regulator 4491603..4493015 Escherichia coli O104:H4 str. 2009EL-2050 13692005 YP_006771965.1 CDS O3M_21730 NC_018650.1 4493258 4494214 R transposase complement(4493258..4494214) Escherichia coli O104:H4 str. 2009EL-2050 13692006 YP_006771966.1 CDS O3M_21735 NC_018650.1 4494681 4495913 D COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein MdtM 4494681..4495913 Escherichia coli O104:H4 str. 2009EL-2050 13692007 YP_006771967.1 CDS O3M_21740 NC_018650.1 4495954 4497234 D COG2733 Predicted membrane protein; inner membrane protein 4495954..4497234 Escherichia coli O104:H4 str. 2009EL-2050 13692008 YP_006771968.1 CDS O3M_21745 NC_018650.1 4497350 4498501 D COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; 2-hydroxyglutaryl-CoA dehydratase 4497350..4498501 Escherichia coli O104:H4 str. 2009EL-2050 13692009 YP_006771969.1 CDS O3M_21750 NC_018650.1 4498511 4499278 D COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); hypothetical protein 4498511..4499278 Escherichia coli O104:H4 str. 2009EL-2050 13692010 YP_006771970.1 CDS O3M_21755 NC_018650.1 4499275 4499532 D hypothetical protein 4499275..4499532 Escherichia coli O104:H4 str. 2009EL-2050 13692011 YP_006771971.1 CDS O3M_21760 NC_018650.1 4499486 4500457 D COG3204 Uncharacterized protein conserved in bacteria; hypothetical protein 4499486..4500457 Escherichia coli O104:H4 str. 2009EL-2050 13692012 YP_006771972.1 CDS O3M_21765 NC_018650.1 4500525 4501703 D COG0477 Permeases of the major facilitator superfamily; inner membrane protein 4500525..4501703 Escherichia coli O104:H4 str. 2009EL-2050 13692013 YP_006771973.1 CDS O3M_21770 NC_018650.1 4501716 4502270 R COG1859 RNA:NAD 2'-phosphotransferase; RNA 2'-phosphotransferase complement(4501716..4502270) Escherichia coli O104:H4 str. 2009EL-2050 13692014 YP_006771974.1 CDS O3M_21775 NC_018650.1 4502520 4503203 D COG3314 Uncharacterized protein conserved in bacteria; hypothetical protein 4502520..4503203 Escherichia coli O104:H4 str. 2009EL-2050 13692015 YP_006771975.1 CDS O3M_21780 NC_018650.1 4503200 4503661 D COG0700 Uncharacterized membrane protein; hypothetical protein 4503200..4503661 Escherichia coli O104:H4 str. 2009EL-2050 13692016 YP_006771976.1 CDS O3M_21785 NC_018650.1 4503674 4504846 D COG0044 Dihydroorotase and related cyclic amidohydrolases; isoaspartyl dipeptidase 4503674..4504846 Escherichia coli O104:H4 str. 2009EL-2050 13692017 YP_006771977.1 CDS O3M_21790 NC_018650.1 4504911 4505822 D COG0583 Transcriptional regulator; cell density-dependent motility repressor 4504911..4505822 Escherichia coli O104:H4 str. 2009EL-2050 13692018 YP_006771978.1 CDS iraD NC_018650.1 4505815 4506207 R DNA replication/recombination/repair protein complement(4505815..4506207) Escherichia coli O104:H4 str. 2009EL-2050 13692019 YP_006771979.1 CDS O3M_21800 NC_018650.1 4506879 4507709 D hypothetical protein 4506879..4507709 Escherichia coli O104:H4 str. 2009EL-2050 13692020 YP_006771980.1 CDS O3M_21805 NC_018650.1 4507850 4508623 R COG2186 Transcriptional regulators; DNA-binding transcriptional repressor UxuR complement(4507850..4508623) Escherichia coli O104:H4 str. 2009EL-2050 13692021 YP_006771981.1 CDS O3M_21810 NC_018650.1 4508622 4508816 D hypothetical protein 4508622..4508816 Escherichia coli O104:H4 str. 2009EL-2050 13692022 YP_006771982.1 CDS O3M_21815 NC_018650.1 4508838 4510298 R COG0246 Mannitol-1-phosphate/altronate dehydrogenases; D-mannonate oxidoreductase complement(4508838..4510298) Escherichia coli O104:H4 str. 2009EL-2050 13692023 YP_006771983.1 CDS O3M_21820 NC_018650.1 4510379 4511563 R COG1312 D-mannonate dehydratase; mannonate dehydratase complement(4510379..4511563) Escherichia coli O104:H4 str. 2009EL-2050 13692024 YP_006771984.1 CDS O3M_21825 NC_018650.1 4511903 4513246 D COG2610 H+/gluconate symporter and related permeases; fructuronate transporter 4511903..4513246 Escherichia coli O104:H4 str. 2009EL-2050 13692025 YP_006771985.1 CDS O3M_21830 NC_018650.1 4513645 4513920 D COG3677 Transposase and inactivated derivatives; IS1 repressor protein insA 4513645..4513920 Escherichia coli O104:H4 str. 2009EL-2050 13692026 YP_006771986.1 CDS O3M_21835 NC_018650.1 4513839 4514342 D COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 4513839..4514342 Escherichia coli O104:H4 str. 2009EL-2050 13692027 YP_006771987.1 CDS O3M_21840 NC_018650.1 4514353 4515030 R hypothetical protein complement(4514353..4515030) Escherichia coli O104:H4 str. 2009EL-2050 13692028 YP_006771988.1 CDS O3M_21845 NC_018650.1 4516231 4516839 R COG1960 Acyl-CoA dehydrogenases; hypothetical protein complement(4516231..4516839) Escherichia coli O104:H4 str. 2009EL-2050 13692029 YP_006771989.1 CDS O3M_21850 NC_018650.1 4516928 4517134 R COG3311 Predicted transcriptional regulator; hypothetical protein complement(4516928..4517134) Escherichia coli O104:H4 str. 2009EL-2050 13692030 YP_006771990.1 CDS O3M_21855 NC_018650.1 4517275 4517541 D hypothetical protein 4517275..4517541 Escherichia coli O104:H4 str. 2009EL-2050 13692031 YP_006771991.1 CDS O3M_21860 NC_018650.1 4517842 4518018 D hemolysin expression modulating protein Hha 4517842..4518018 Escherichia coli O104:H4 str. 2009EL-2050 13692032 YP_006771992.1 CDS O3M_21865 NC_018650.1 4518759 4519328 D hypothetical protein 4518759..4519328 Escherichia coli O104:H4 str. 2009EL-2050 13692033 YP_006771993.1 CDS O3M_21870 NC_018650.1 4519582 4519989 D COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 4519582..4519989 Escherichia coli O104:H4 str. 2009EL-2050 13692034 YP_006771994.1 CDS O3M_21875 NC_018650.1 4519977 4520411 D hypothetical protein 4519977..4520411 Escherichia coli O104:H4 str. 2009EL-2050 13692035 YP_006771995.1 CDS O3M_21880 NC_018650.1 4520745 4521146 D COG2963 Transposase and inactivated derivatives; transposase, IS3 family protein 4520745..4521146 Escherichia coli O104:H4 str. 2009EL-2050 13692036 YP_006771996.1 CDS O3M_21885 NC_018650.1 4521143 4521490 D COG3436 Transposase and inactivated derivatives; transposase 4521143..4521490 Escherichia coli O104:H4 str. 2009EL-2050 13692037 YP_006771997.1 CDS O3M_21890 NC_018650.1 4521540 4522925 D COG3436 Transposase and inactivated derivatives; transposase 4521540..4522925 Escherichia coli O104:H4 str. 2009EL-2050 13692038 YP_006771998.1 CDS O3M_21895 NC_018650.1 4523164 4524522 R COG4222 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4523164..4524522) Escherichia coli O104:H4 str. 2009EL-2050 13692039 YP_006771999.1 CDS O3M_21900 NC_018650.1 4524901 4525110 D hypothetical protein 4524901..4525110 Escherichia coli O104:H4 str. 2009EL-2050 13692040 YP_006772000.1 CDS O3M_21905 NC_018650.1 4525273 4525530 R hypothetical protein complement(4525273..4525530) Escherichia coli O104:H4 str. 2009EL-2050 13692041 YP_006772001.1 CDS O3M_21910 NC_018650.1 4526448 4526969 D COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor FecI 4526448..4526969 Escherichia coli O104:H4 str. 2009EL-2050 13692042 YP_006772002.1 CDS O3M_21915 NC_018650.1 4526966 4527919 D COG3712 Fe2+-dicitrate sensor, membrane component; fec operon regulator FecR 4526966..4527919 Escherichia coli O104:H4 str. 2009EL-2050 13692043 YP_006772003.1 CDS O3M_21920 NC_018650.1 4528006 4530330 D KpLE2 phage-like element; COG4772 Outer membrane receptor for Fe3+-dicitrate; ferric citrate outer membrane transporter 4528006..4530330 Escherichia coli O104:H4 str. 2009EL-2050 13692044 YP_006772004.1 CDS fecB NC_018650.1 4530375 4531277 D COG4594 ABC-type Fe3+-citrate transport system, periplasmic component; iron-dicitrate transporter substrate-binding subunit 4530375..4531277 Escherichia coli O104:H4 str. 2009EL-2050 13692045 YP_006772005.1 CDS fecC NC_018650.1 4531274 4532272 D COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-dicitrate transporter permease subunit 4531274..4532272 Escherichia coli O104:H4 str. 2009EL-2050 13692046 YP_006772006.1 CDS fecD NC_018650.1 4532269 4533225 D COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-dicitrate transporter subunit FecD 4532269..4533225 Escherichia coli O104:H4 str. 2009EL-2050 13692047 YP_006772007.1 CDS fecE NC_018650.1 4533226 4533993 D COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-dicitrate transporter ATP-binding subunit 4533226..4533993 Escherichia coli O104:H4 str. 2009EL-2050 13692048 YP_006772008.1 CDS O3M_21945 NC_018650.1 4534551 4534964 R COG2085 Predicted dinucleotide-binding enzymes; KpLE2 phage-like element complement(4534551..4534964) Escherichia coli O104:H4 str. 2009EL-2050 13692049 YP_006772009.1 CDS O3M_21955 NC_018650.1 4535459 4536982 R COG3344 Retron-type reverse transcriptase; group II intron encoded reverse transcriptase/maturase complement(4535459..4536982) Escherichia coli O104:H4 str. 2009EL-2050 13692050 YP_006772010.1 CDS O3M_21965 NC_018650.1 4538055 4538357 R COG2963 Transposase and inactivated derivatives; IS911; transposase ORF A, IS911 complement(4538055..4538357) Escherichia coli O104:H4 str. 2009EL-2050 13692051 YP_006772011.1 CDS O3M_21970 NC_018650.1 4538564 4539385 D COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase family protein 4538564..4539385 Escherichia coli O104:H4 str. 2009EL-2050 13692052 YP_006772012.1 CDS O3M_21975 NC_018650.1 4539388 4540476 D COG0438 Glycosyltransferase; Glycosyl transferase 4539388..4540476 Escherichia coli O104:H4 str. 2009EL-2050 13692053 YP_006772013.1 CDS O3M_21980 NC_018650.1 4540481 4541431 D COG2990 Uncharacterized protein conserved in bacteria; regulator of virG protein 4540481..4541431 Escherichia coli O104:H4 str. 2009EL-2050 13692054 YP_006772014.1 CDS O3M_21985 NC_018650.1 4541496 4542440 D COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 4541496..4542440 Escherichia coli O104:H4 str. 2009EL-2050 13692055 YP_006772015.1 CDS O3M_21990 NC_018650.1 4543047 4543760 D COG2801 Transposase and inactivated derivatives; hypothetical protein 4543047..4543760 Escherichia coli O104:H4 str. 2009EL-2050 13692056 YP_006772016.1 CDS O3M_21995 NC_018650.1 4543908 4545911 D COG1292 Choline-glycine betaine transporter; betaine-carnitine-choline transporter family member BetU 4543908..4545911 Escherichia coli O104:H4 str. 2009EL-2050 13692057 YP_006772017.1 CDS O3M_22000 NC_018650.1 4545974 4547251 D COG4325 Predicted membrane protein; hypothetical protein 4545974..4547251 Escherichia coli O104:H4 str. 2009EL-2050 13692058 YP_006772018.1 CDS O3M_22005 NC_018650.1 4547497 4548153 D COG1309 Transcriptional regulator; HTH regulator, TetR family protein 4547497..4548153 Escherichia coli O104:H4 str. 2009EL-2050 13692059 YP_006772019.1 CDS O3M_22015 NC_018650.1 4548601 4549026 D COG2963 Transposase and inactivated derivatives; IS66 transposase 4548601..4549026 Escherichia coli O104:H4 str. 2009EL-2050 13692060 YP_006772020.1 CDS O3M_22020 NC_018650.1 4549023 4549373 D COG3436 Transposase and inactivated derivatives; IS66 transposase 4549023..4549373 Escherichia coli O104:H4 str. 2009EL-2050 13692061 YP_006772021.1 CDS O3M_22025 NC_018650.1 4549404 4551017 D COG3436 Transposase and inactivated derivatives; IS element transposase 4549404..4551017 Escherichia coli O104:H4 str. 2009EL-2050 13692062 YP_006772022.1 CDS O3M_22030 NC_018650.1 4551093 4551356 R hypothetical protein complement(4551093..4551356) Escherichia coli O104:H4 str. 2009EL-2050 13692063 YP_006772023.1 CDS O3M_22035 NC_018650.1 4551984 4552100 D hypothetical protein 4551984..4552100 Escherichia coli O104:H4 str. 2009EL-2050 13692064 YP_006772024.1 CDS O3M_22040 NC_018650.1 4552101 4552199 D acetolactate synthase 1 regulatory subunit 4552101..4552199 Escherichia coli O104:H4 str. 2009EL-2050 13692065 YP_006772025.1 CDS O3M_22045 NC_018650.1 4552201 4552983 R COG1349 Transcriptional regulators of sugar metabolism; transcriptional regulator complement(4552201..4552983) Escherichia coli O104:H4 str. 2009EL-2050 13692066 YP_006772026.1 CDS O3M_22050 NC_018650.1 4553289 4554209 D COG0524 Sugar kinases, ribokinase family; ribokinase sugar kinase 4553289..4554209 Escherichia coli O104:H4 str. 2009EL-2050 13692067 YP_006772027.1 CDS O3M_22055 NC_018650.1 4554237 4555553 D COG0738 Fucose permease; L-fucose permease 4554237..4555553 Escherichia coli O104:H4 str. 2009EL-2050 13692068 YP_006772028.1 CDS O3M_22060 NC_018650.1 4555565 4556578 D Deoxyribose specific mutarotase 4555565..4556578 Escherichia coli O104:H4 str. 2009EL-2050 13692069 YP_006772029.1 CDS O3M_22070 NC_018650.1 4557501 4558757 R COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC complement(4557501..4558757) Escherichia coli O104:H4 str. 2009EL-2050 13692151 YP_006772030.1 CDS O3M_22075 NC_018650.1 4558770 4559057 R COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system transporter subunit IIB complement(4558770..4559057) Escherichia coli O104:H4 str. 2009EL-2050 13692152 YP_006772031.1 CDS O3M_22080 NC_018650.1 4559073 4559516 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system transporter subunit IIA complement(4559073..4559516) Escherichia coli O104:H4 str. 2009EL-2050 13692153 YP_006772032.1 CDS O3M_22085 NC_018650.1 4559787 4560818 D COG1609 Transcriptional regulators; transcriptional regulator 4559787..4560818 Escherichia coli O104:H4 str. 2009EL-2050 13692154 YP_006772033.1 CDS O3M_22095 NC_018650.1 4561998 4562156 R COG0207 Thymidylate synthase; hypothetical protein complement(4561998..4562156) Escherichia coli O104:H4 str. 2009EL-2050 13692155 YP_006772034.1 CDS O3M_22100 NC_018650.1 4562588 4562809 R hypothetical protein complement(4562588..4562809) Escherichia coli O104:H4 str. 2009EL-2050 13692156 YP_006772035.1 CDS O3M_22105 NC_018650.1 4562788 4562952 R hypothetical protein complement(4562788..4562952) Escherichia coli O104:H4 str. 2009EL-2050 13692157 YP_006772036.1 CDS O3M_22110 NC_018650.1 4563064 4563753 R COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; N-acetylmannosamine-6-phosphate 2-epimerase complement(4563064..4563753) Escherichia coli O104:H4 str. 2009EL-2050 13692158 YP_006772037.1 CDS O3M_22115 NC_018650.1 4563753 4565309 R COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose-specific transporter subunit IIABC complement(4563753..4565309) Escherichia coli O104:H4 str. 2009EL-2050 13692159 YP_006772038.1 CDS O3M_22120 NC_018650.1 4565475 4566299 D COG1737 Transcriptional regulators; transcriptional regulator 4565475..4566299 Escherichia coli O104:H4 str. 2009EL-2050 13692160 YP_006772039.1 CDS O3M_22125 NC_018650.1 4566471 4566974 R COG1662 Transposase and inactivated derivatives, IS1 family; IS1; transposase ORF B, IS1 complement(4566471..4566974) Escherichia coli O104:H4 str. 2009EL-2050 13692161 YP_006772040.1 CDS O3M_22130 NC_018650.1 4566893 4567168 R KpLE2 phage-like element; COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA complement(4566893..4567168) Escherichia coli O104:H4 str. 2009EL-2050 13692162 YP_006772041.1 CDS O3M_22135 NC_018650.1 4567210 4567839 D hypothetical protein 4567210..4567839 Escherichia coli O104:H4 str. 2009EL-2050 13692163 YP_006772042.1 CDS O3M_22140 NC_018650.1 4567890 4568966 R COG3177 Uncharacterized conserved protein; Filamentation induced by cAMP protein Fic complement(4567890..4568966) Escherichia coli O104:H4 str. 2009EL-2050 13692164 YP_006772043.1 CDS O3M_22145 NC_018650.1 4569596 4569892 R COG1396 Predicted transcriptional regulators; transcriptional regulator complement(4569596..4569892) Escherichia coli O104:H4 str. 2009EL-2050 13692165 YP_006772044.1 CDS O3M_22150 NC_018650.1 4570860 4571063 D COG3677 Transposase and inactivated derivatives; hypothetical protein 4570860..4571063 Escherichia coli O104:H4 str. 2009EL-2050 13692166 YP_006772045.1 CDS O3M_22155 NC_018650.1 4570996 4571508 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 4570996..4571508 Escherichia coli O104:H4 str. 2009EL-2050 13692167 YP_006772046.1 CDS O3M_22160 NC_018650.1 4571562 4571942 D COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); hypothetical protein 4571562..4571942 Escherichia coli O104:H4 str. 2009EL-2050 13692168 YP_006772047.1 CDS O3M_22165 NC_018650.1 4572187 4573059 D COG3440 Predicted restriction endonuclease; hypothetical protein 4572187..4573059 Escherichia coli O104:H4 str. 2009EL-2050 13692169 YP_006772048.1 CDS O3M_22170 NC_018650.1 4573427 4573720 D hypothetical protein 4573427..4573720 Escherichia coli O104:H4 str. 2009EL-2050 13692170 YP_006772049.1 CDS O3M_22175 NC_018650.1 4573806 4575011 D COG4227 Antirestriction protein; hypothetical protein 4573806..4575011 Escherichia coli O104:H4 str. 2009EL-2050 13692171 YP_006772050.1 CDS O3M_22180 NC_018650.1 4575021 4576640 D COG3481 Predicted HD-superfamily hydrolase; hypothetical protein 4575021..4576640 Escherichia coli O104:H4 str. 2009EL-2050 13692172 YP_006772051.1 CDS O3M_22185 NC_018650.1 4576630 4577556 D COG0582 Integrase; hypothetical protein 4576630..4577556 Escherichia coli O104:H4 str. 2009EL-2050 13692173 YP_006772052.1 CDS O3M_22190 NC_018650.1 4577986 4579005 D COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase, Zn-dependent and NAD(P)-binding protein 4577986..4579005 Escherichia coli O104:H4 str. 2009EL-2050 13692175 YP_006772053.1 CDS idnK NC_018650.1 4579009 4579572 R COG3265 Gluconate kinase; D-gluconate kinase complement(4579009..4579572) Escherichia coli O104:H4 str. 2009EL-2050 13692176 YP_006772054.1 CDS O3M_22200 NC_018650.1 4579789 4580820 D COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; L-idonate 5-dehydrogenase 4579789..4580820 Escherichia coli O104:H4 str. 2009EL-2050 13692177 YP_006772055.1 CDS O3M_22205 NC_018650.1 4580844 4581608 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); gluconate 5-dehydrogenase 4580844..4581608 Escherichia coli O104:H4 str. 2009EL-2050 13692178 YP_006772056.1 CDS O3M_22210 NC_018650.1 4581673 4582992 D COG2610 H+/gluconate symporter and related permeases; Gnt-II system L-idonate transporter 4581673..4582992 Escherichia coli O104:H4 str. 2009EL-2050 13692179 YP_006772057.1 CDS O3M_22215 NC_018650.1 4583059 4584057 D COG1609 Transcriptional regulators; DNA-binding transcriptional repressor, 5-gluconate-binding protein 4583059..4584057 Escherichia coli O104:H4 str. 2009EL-2050 13692180 YP_006772058.1 CDS O3M_22220 NC_018650.1 4584135 4585637 D COG0433 Predicted ATPase; ATPase 4584135..4585637 Escherichia coli O104:H4 str. 2009EL-2050 13692181 YP_006772059.1 CDS O3M_22225 NC_018650.1 4585756 4586838 R COG0795 Predicted permeases; lipopolysaccharide ABC transporter permease complement(4585756..4586838) Escherichia coli O104:H4 str. 2009EL-2050 13692182 YP_006772060.1 CDS O3M_22230 NC_018650.1 4586838 4587938 R COG0795 Predicted permeases; lipopolysaccharide ABC transporter permease LptF complement(4586838..4587938) Escherichia coli O104:H4 str. 2009EL-2050 13692183 YP_006772061.1 CDS O3M_22235 NC_018650.1 4588205 4589716 D COG0260 Leucyl aminopeptidase; multifunctional aminopeptidase A 4588205..4589716 Escherichia coli O104:H4 str. 2009EL-2050 13692184 YP_006772062.1 CDS O3M_22240 NC_018650.1 4589850 4590293 D COG2927 DNA polymerase III, chi subunit; DNA polymerase III subunit chi 4589850..4590293 Escherichia coli O104:H4 str. 2009EL-2050 13692185 YP_006772063.1 CDS valS NC_018650.1 4590293 4593148 D COG0525 Valyl-tRNA synthetase; valyl-tRNA synthetase 4590293..4593148 Escherichia coli O104:H4 str. 2009EL-2050 13692186 YP_006772064.1 CDS O3M_22250 NC_018650.1 4593204 4594400 R COG4269 Predicted membrane protein; hypothetical protein complement(4593204..4594400) Escherichia coli O104:H4 str. 2009EL-2050 13692187 YP_006772065.1 CDS O3M_22255 NC_018650.1 4594593 4595096 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 4594593..4595096 Escherichia coli O104:H4 str. 2009EL-2050 13692188 YP_006772066.1 CDS O3M_22260 NC_018650.1 4595142 4595558 R COG3076 Uncharacterized protein conserved in bacteria; RNase E inhibitor protein complement(4595142..4595558) Escherichia coli O104:H4 str. 2009EL-2050 13692189 YP_006772067.1 CDS O3M_22265 NC_018650.1 4595720 4596724 D COG0078 Ornithine carbamoyltransferase; ornithine carbamoyltransferase subunit I 4595720..4596724 Escherichia coli O104:H4 str. 2009EL-2050 13692190 YP_006772068.1 CDS O3M_22270 NC_018650.1 4596825 4597055 R hypothetical protein complement(4596825..4597055) Escherichia coli O104:H4 str. 2009EL-2050 13692191 YP_006772069.1 CDS O3M_22275 NC_018650.1 4597307 4597582 D COG3677 Transposase and inactivated derivatives; InsA 4597307..4597582 Escherichia coli O104:H4 str. 2009EL-2050 13692192 YP_006772070.1 CDS O3M_22280 NC_018650.1 4597628 4598005 D COG1662 Transposase and inactivated derivatives, IS1 family; InsAB 4597628..4598005 Escherichia coli O104:H4 str. 2009EL-2050 13692193 YP_006772071.1 CDS O3M_22285 NC_018650.1 4598016 4599164 R hypothetical protein complement(4598016..4599164) Escherichia coli O104:H4 str. 2009EL-2050 13692194 YP_006772072.1 CDS O3M_22290 NC_018650.1 4599287 4599739 R COG2731 Beta-galactosidase, beta subunit; hypothetical protein complement(4599287..4599739) Escherichia coli O104:H4 str. 2009EL-2050 13692195 YP_006772073.1 CDS O3M_22295 NC_018650.1 4599884 4600477 R COG1309 Transcriptional regulator; transcriptional regulator complement(4599884..4600477) Escherichia coli O104:H4 str. 2009EL-2050 13692196 YP_006772074.1 CDS O3M_22300 NC_018650.1 4600548 4601261 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 4600548..4601261 Escherichia coli O104:H4 str. 2009EL-2050 13692197 YP_006772075.1 CDS O3M_22305 NC_018650.1 4601392 4601787 D COG0251 Putative translation initiation inhibitor, yjgF family; mRNA endoribonuclease 4601392..4601787 Escherichia coli O104:H4 str. 2009EL-2050 13692198 YP_006772076.1 CDS O3M_22310 NC_018650.1 4602011 4602202 D pyrBI operon leader peptide 4602011..4602202 Escherichia coli O104:H4 str. 2009EL-2050 13692199 YP_006772077.1 CDS pyrB NC_018650.1 4602206 4603141 D COG0540 Aspartate carbamoyltransferase, catalytic chain; aspartate carbamoyltransferase catalytic subunit 4602206..4603141 Escherichia coli O104:H4 str. 2009EL-2050 13692200 YP_006772078.1 CDS O3M_22320 NC_018650.1 4603154 4603615 D COG1781 Aspartate carbamoyltransferase, regulatory subunit; aspartate carbamoyltransferase regulatory subunit 4603154..4603615 Escherichia coli O104:H4 str. 2009EL-2050 13692201 YP_006772079.1 CDS O3M_22325 NC_018650.1 4603688 4604074 D COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 4603688..4604074 Escherichia coli O104:H4 str. 2009EL-2050 13692202 YP_006772080.1 CDS O3M_22330 NC_018650.1 4604351 4605331 D COG3547 Transposase and inactivated derivatives; IS621 transposase 4604351..4605331 Escherichia coli O104:H4 str. 2009EL-2050 13692203 YP_006772081.1 CDS O3M_22335 NC_018650.1 4605559 4608255 R COG0474 Cation transport ATPase; magnesium-transporting ATPase MgtA complement(4605559..4608255) Escherichia coli O104:H4 str. 2009EL-2050 13692204 YP_006772082.1 CDS treR NC_018650.1 4608634 4609581 D COG1609 Transcriptional regulators; trehalose repressor 4608634..4609581 Escherichia coli O104:H4 str. 2009EL-2050 13692205 YP_006772083.1 CDS O3M_22345 NC_018650.1 4609703 4611121 D COG1264 Phosphotransferase system IIB components; PTS system trehalose(maltose)-specific transporter subunit IIBC 4609703..4611121 Escherichia coli O104:H4 str. 2009EL-2050 13692206 YP_006772084.1 CDS O3M_22350 NC_018650.1 4611171 4612826 D COG0366 Glycosidases; trehalose-6-phosphate hydrolase 4611171..4612826 Escherichia coli O104:H4 str. 2009EL-2050 13692207 YP_006772085.1 CDS O3M_22355 NC_018650.1 4613229 4615367 D COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; anaerobic ribonucleoside triphosphate reductase 4613229..4615367 Escherichia coli O104:H4 str. 2009EL-2050 13692208 YP_006772086.1 CDS nrdG NC_018650.1 4615525 4615989 D COG0602 Organic radical activating enzymes; anaerobic ribonucleotide reductase-activating protein 4615525..4615989 Escherichia coli O104:H4 str. 2009EL-2050 13692209 YP_006772087.1 CDS O3M_22365 NC_018650.1 4616034 4616420 R COG3783 Soluble cytochrome b562; cytochrome b562 complement(4616034..4616420) Escherichia coli O104:H4 str. 2009EL-2050 13692210 YP_006772088.1 CDS O3M_22370 NC_018650.1 4616603 4617943 R COG0312 Predicted Zn-dependent proteases and their inactivated homologs; peptidase PmbA complement(4616603..4617943) Escherichia coli O104:H4 str. 2009EL-2050 13692211 YP_006772089.1 CDS O3M_22375 NC_018650.1 4618049 4618600 D COG3028 Uncharacterized protein conserved in bacteria; hypothetical protein 4618049..4618600 Escherichia coli O104:H4 str. 2009EL-2050 13692212 YP_006772090.1 CDS O3M_22380 NC_018650.1 4618751 4620124 R COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase complement(4618751..4620124) Escherichia coli O104:H4 str. 2009EL-2050 13692213 YP_006772091.1 CDS O3M_22385 NC_018650.1 4620300 4621298 D COG0158 Fructose-1,6-bisphosphatase; fructose-1,6-bisphosphatase 4620300..4621298 Escherichia coli O104:H4 str. 2009EL-2050 13692214 YP_006772092.1 CDS O3M_22390 NC_018650.1 4621331 4622326 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; inner membrane ABC transporter permease YjfF complement(4621331..4622326) Escherichia coli O104:H4 str. 2009EL-2050 13692215 YP_006772093.1 CDS O3M_22395 NC_018650.1 4622313 4623335 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease complement(4622313..4623335) Escherichia coli O104:H4 str. 2009EL-2050 13692216 YP_006772094.1 CDS O3M_22400 NC_018650.1 4623349 4624851 R COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein complement(4623349..4624851) Escherichia coli O104:H4 str. 2009EL-2050 13692217 YP_006772095.1 CDS O3M_22405 NC_018650.1 4625161 4626117 R COG1879 ABC-type sugar transport system, periplasmic component; sugar transporter subunit complement(4625161..4626117) Escherichia coli O104:H4 str. 2009EL-2050 13692218 YP_006772096.1 CDS O3M_22410 NC_018650.1 4626427 4626957 D COG0221 Inorganic pyrophosphatase; inorganic pyrophosphatase 4626427..4626957 Escherichia coli O104:H4 str. 2009EL-2050 13692219 YP_006772097.1 CDS O3M_22415 NC_018650.1 4627037 4627387 R COG2337 Growth inhibitor; toxin ChpB complement(4627037..4627387) Escherichia coli O104:H4 str. 2009EL-2050 13692220 YP_006772098.1 CDS O3M_22420 NC_018650.1 4627381 4627632 R COG2336 Growth regulator; antitoxin ChpS complement(4627381..4627632) Escherichia coli O104:H4 str. 2009EL-2050 13692221 YP_006772099.1 CDS O3M_22425 NC_018650.1 4627844 4628185 R COG2105 Uncharacterized conserved protein; hypothetical protein complement(4627844..4628185) Escherichia coli O104:H4 str. 2009EL-2050 13692222 YP_006772100.1 CDS O3M_22430 NC_018650.1 4628188 4631967 R COG2911 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4628188..4631967) Escherichia coli O104:H4 str. 2009EL-2050 13692223 YP_006772101.1 CDS O3M_22435 NC_018650.1 4631964 4633697 R COG0729 Outer membrane protein; surface antigen complement(4631964..4633697) Escherichia coli O104:H4 str. 2009EL-2050 13692224 YP_006772102.1 CDS O3M_22440 NC_018650.1 4633667 4633795 R COG1131 ABC-type multidrug transport system, ATPase component; hypothetical protein complement(4633667..4633795) Escherichia coli O104:H4 str. 2009EL-2050 13692225 YP_006772103.1 CDS O3M_22445 NC_018650.1 4633903 4634541 D COG0225 Peptide methionine sulfoxide reductase; methionine sulfoxide reductase A 4633903..4634541 Escherichia coli O104:H4 str. 2009EL-2050 13692226 YP_006772104.1 CDS O3M_22450 NC_018650.1 4634864 4636207 D COG1253 Hemolysins and related proteins containing CBS domains; inner membrane protein 4634864..4636207 Escherichia coli O104:H4 str. 2009EL-2050 13692227 YP_006772105.1 CDS O3M_22455 NC_018650.1 4636269 4636475 R COG1117 ABC-type phosphate transport system, ATPase component; hypothetical protein complement(4636269..4636475) Escherichia coli O104:H4 str. 2009EL-2050 13692228 YP_006772106.1 CDS O3M_22460 NC_018650.1 4636800 4637357 D COG3054 Predicted transcriptional regulator; transcriptional regulator 4636800..4637357 Escherichia coli O104:H4 str. 2009EL-2050 13692229 YP_006772107.1 CDS O3M_22465 NC_018650.1 4637347 4638087 R COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; adenosine-3'(2'),5'-bisphosphate nucleotidase complement(4637347..4638087) Escherichia coli O104:H4 str. 2009EL-2050 13692230 YP_006772108.1 CDS cpdB NC_018650.1 4638277 4640220 D COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase 4638277..4640220 Escherichia coli O104:H4 str. 2009EL-2050 13692231 YP_006772109.1 CDS O3M_22475 NC_018650.1 4640349 4640729 R COG1733 Predicted transcriptional regulators; hypothetical protein complement(4640349..4640729) Escherichia coli O104:H4 str. 2009EL-2050 13692313 YP_006772110.1 CDS O3M_22480 NC_018650.1 4640818 4641678 D COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD(P)H:quinone oxidoreductase 4640818..4641678 Escherichia coli O104:H4 str. 2009EL-2050 13692314 YP_006772111.1 CDS O3M_22485 NC_018650.1 4641786 4642751 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; inner membrane protein 4641786..4642751 Escherichia coli O104:H4 str. 2009EL-2050 13692315 YP_006772112.1 CDS O3M_22490 NC_018650.1 4642859 4643521 D COG2846 Regulator of cell morphogenesis and NO signaling; iron-sulfur cluster repair di-iron protein 4642859..4643521 Escherichia coli O104:H4 str. 2009EL-2050 13692316 YP_006772113.1 CDS O3M_22495 NC_018650.1 4643566 4644978 R COG1113 Gamma-aminobutyrate permease and related permeases; D-alanine/D-serine/glycine permease complement(4643566..4644978) Escherichia coli O104:H4 str. 2009EL-2050 13692317 YP_006772114.1 CDS O3M_22500 NC_018650.1 4645287 4645907 R COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; peptidyl-prolyl cis-trans isomerase complement(4645287..4645907) Escherichia coli O104:H4 str. 2009EL-2050 13692318 YP_006772115.1 CDS O3M_22505 NC_018650.1 4646126 4646764 D COG3061 Cell envelope opacity-associated protein A; cell envelope opacity-associated protein 4646126..4646764 Escherichia coli O104:H4 str. 2009EL-2050 13692319 YP_006772116.1 CDS O3M_22510 NC_018650.1 4646899 4648107 R COG0675 Transposase and inactivated derivatives; transposase complement(4646899..4648107) Escherichia coli O104:H4 str. 2009EL-2050 13692320 YP_006772117.1 CDS O3M_22515 NC_018650.1 4648115 4648546 D COG1943 Transposase and inactivated derivatives; transposase 4648115..4648546 Escherichia coli O104:H4 str. 2009EL-2050 13692321 YP_006772118.1 CDS O3M_22520 NC_018650.1 4649169 4649963 D hypothetical protein 4649169..4649963 Escherichia coli O104:H4 str. 2009EL-2050 13692322 YP_006772119.1 CDS rplI NC_018650.1 4650034 4650483 R COG0359 Ribosomal protein L9; 50S ribosomal protein L9 complement(4650034..4650483) Escherichia coli O104:H4 str. 2009EL-2050 13692323 YP_006772120.1 CDS rpsR NC_018650.1 4650525 4650752 R COG0238 Ribosomal protein S18; 30S ribosomal protein S18 complement(4650525..4650752) Escherichia coli O104:H4 str. 2009EL-2050 13692324 YP_006772121.1 CDS O3M_22535 NC_018650.1 4650757 4651071 R COG2965 Primosomal replication protein N; primosomal replication protein N complement(4650757..4651071) Escherichia coli O104:H4 str. 2009EL-2050 13692325 YP_006772122.1 CDS rpsF NC_018650.1 4651078 4651473 R COG0360 Ribosomal protein S6; 30S ribosomal protein S6 complement(4651078..4651473) Escherichia coli O104:H4 str. 2009EL-2050 13692326 YP_006772123.1 CDS O3M_22545 NC_018650.1 4651800 4652075 D hypothetical protein 4651800..4652075 Escherichia coli O104:H4 str. 2009EL-2050 13692327 YP_006772124.1 CDS O3M_22550 NC_018650.1 4652150 4652701 R COG3477 Predicted periplasmic/secreted protein; inner membrane protein yagU complement(4652150..4652701) Escherichia coli O104:H4 str. 2009EL-2050 13692328 YP_006772125.1 CDS sgaE NC_018650.1 4652798 4653484 R COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase complement(4652798..4653484) Escherichia coli O104:H4 str. 2009EL-2050 13692329 YP_006772126.1 CDS O3M_22560 NC_018650.1 4653484 4654338 R COG3623 Putative L-xylulose-5-phosphate 3-epimerase; L-xylulose 5-phosphate 3-epimerase complement(4653484..4654338) Escherichia coli O104:H4 str. 2009EL-2050 13692330 YP_006772127.1 CDS ulaD NC_018650.1 4654348 4654998 R COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-keto-L-gulonate-6-phosphate decarboxylase complement(4654348..4654998) Escherichia coli O104:H4 str. 2009EL-2050 13692331 YP_006772128.1 CDS O3M_22570 NC_018650.1 4655012 4655476 R COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system L-ascorbate-specific transporter subunit IIA complement(4655012..4655476) Escherichia coli O104:H4 str. 2009EL-2050 13692332 YP_006772129.1 CDS O3M_22575 NC_018650.1 4655486 4655791 R COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system L-ascorbate-specific transporter subunit IIB complement(4655486..4655791) Escherichia coli O104:H4 str. 2009EL-2050 13692333 YP_006772130.1 CDS ulaA NC_018650.1 4655807 4657204 R COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC complement(4655807..4657204) Escherichia coli O104:H4 str. 2009EL-2050 13692334 YP_006772131.1 CDS O3M_22585 NC_018650.1 4657559 4658623 D COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; L-ascorbate 6-phosphate lactonase 4657559..4658623 Escherichia coli O104:H4 str. 2009EL-2050 13692335 YP_006772132.1 CDS O3M_22590 NC_018650.1 4658731 4659486 D COG1349 Transcriptional regulators of sugar metabolism; transcriptional repressor UlaR 4658731..4659486 Escherichia coli O104:H4 str. 2009EL-2050 13692336 YP_006772133.1 CDS O3M_22595 NC_018650.1 4659483 4660232 R COG1073 Hydrolases of the alpha/beta superfamily; esterase complement(4659483..4660232) Escherichia coli O104:H4 str. 2009EL-2050 13692337 YP_006772134.1 CDS O3M_22600 NC_018650.1 4660414 4660743 D biofilm stress and motility protein A 4660414..4660743 Escherichia coli O104:H4 str. 2009EL-2050 13692338 YP_006772135.1 CDS O3M_22605 NC_018650.1 4660892 4661167 D hypothetical protein 4660892..4661167 Escherichia coli O104:H4 str. 2009EL-2050 13692339 YP_006772136.1 CDS O3M_22610 NC_018650.1 4661284 4662909 R COG1960 Acyl-CoA dehydrogenases; isovaleryl CoA dehydrogenase complement(4661284..4662909) Escherichia coli O104:H4 str. 2009EL-2050 13692340 YP_006772137.1 CDS O3M_22615 NC_018650.1 4662993 4664156 R COG0754 Glutathionylspermidine synthase; synthetase/amidase complement(4662993..4664156) Escherichia coli O104:H4 str. 2009EL-2050 13692341 YP_006772138.1 CDS O3M_22620 NC_018650.1 4664159 4664797 R hypothetical protein complement(4664159..4664797) Escherichia coli O104:H4 str. 2009EL-2050 13692342 YP_006772139.1 CDS O3M_22625 NC_018650.1 4664807 4665040 R COG3766 Predicted membrane protein; inner membrane protein complement(4664807..4665040) Escherichia coli O104:H4 str. 2009EL-2050 13692343 YP_006772140.1 CDS O3M_22630 NC_018650.1 4665095 4665205 R COG3766 Predicted membrane protein; inner membrane protein complement(4665095..4665205) Escherichia coli O104:H4 str. 2009EL-2050 13692344 YP_006772141.1 CDS O3M_22635 NC_018650.1 4665223 4665882 R hypothetical protein complement(4665223..4665882) Escherichia coli O104:H4 str. 2009EL-2050 13692345 YP_006772142.1 CDS O3M_22640 NC_018650.1 4665933 4666631 R COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription; transcriptional regulator effector protein complement(4665933..4666631) Escherichia coli O104:H4 str. 2009EL-2050 13692346 YP_006772143.1 CDS O3M_22645 NC_018650.1 4666650 4667051 R COG3789 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4666650..4667051) Escherichia coli O104:H4 str. 2009EL-2050 13692347 YP_006772144.1 CDS O3M_22650 NC_018650.1 4667178 4667909 R COG0566 rRNA methylases; 23S rRNA (guanosine-2'-O-)-methyltransferase complement(4667178..4667909) Escherichia coli O104:H4 str. 2009EL-2050 13692348 YP_006772145.1 CDS O3M_22655 NC_018650.1 4668089 4670530 R COG0557 Exoribonuclease R; exoribonuclease R complement(4668089..4670530) Escherichia coli O104:H4 str. 2009EL-2050 13692349 YP_006772146.1 CDS O3M_22660 NC_018650.1 4670569 4670994 R COG1959 Predicted transcriptional regulator; transcriptional repressor NsrR complement(4670569..4670994) Escherichia coli O104:H4 str. 2009EL-2050 13692350 YP_006772147.1 CDS O3M_22665 NC_018650.1 4671199 4672497 R COG0104 Adenylosuccinate synthase; adenylosuccinate synthetase complement(4671199..4672497) Escherichia coli O104:H4 str. 2009EL-2050 13692351 YP_006772148.1 CDS O3M_22670 NC_018650.1 4672601 4672798 R COG3242 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4672601..4672798) Escherichia coli O104:H4 str. 2009EL-2050 13692352 YP_006772149.1 CDS O3M_22675 NC_018650.1 4672880 4673884 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; FtsH protease regulator HflC complement(4672880..4673884) Escherichia coli O104:H4 str. 2009EL-2050 13692353 YP_006772150.1 CDS O3M_22680 NC_018650.1 4673887 4675146 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; FtsH protease regulator HflK complement(4673887..4675146) Escherichia coli O104:H4 str. 2009EL-2050 13692354 YP_006772151.1 CDS O3M_22685 NC_018650.1 4675232 4676512 R COG2262 GTPases; GTPase HflX complement(4675232..4676512) Escherichia coli O104:H4 str. 2009EL-2050 13692355 YP_006772152.1 CDS hfq NC_018650.1 4676589 4676897 R COG1923 Uncharacterized host factor I protein; RNA-binding protein Hfq complement(4676589..4676897) Escherichia coli O104:H4 str. 2009EL-2050 13692356 YP_006772153.1 CDS miaA NC_018650.1 4676983 4677933 R COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA delta(2)-isopentenylpyrophosphate transferase complement(4676983..4677933) Escherichia coli O104:H4 str. 2009EL-2050 13692357 YP_006772154.1 CDS mutL NC_018650.1 4677926 4679773 R COG0323 DNA mismatch repair enzyme (predicted ATPase); DNA mismatch repair protein complement(4677926..4679773) Escherichia coli O104:H4 str. 2009EL-2050 13692358 YP_006772155.1 CDS O3M_22705 NC_018650.1 4679783 4681120 R COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-l-alanine amidase II complement(4679783..4681120) Escherichia coli O104:H4 str. 2009EL-2050 13692359 YP_006772156.1 CDS O3M_22710 NC_018650.1 4681139 4681600 R COG0802 Predicted ATPase or kinase; ADP-binding protein complement(4681139..4681600) Escherichia coli O104:H4 str. 2009EL-2050 13692360 YP_006772157.1 CDS O3M_22715 NC_018650.1 4681572 4683119 R COG0062 Uncharacterized conserved protein; carbohydrate kinase complement(4681572..4683119) Escherichia coli O104:H4 str. 2009EL-2050 13692361 YP_006772158.1 CDS O3M_22720 NC_018650.1 4683118 4684257 D COG1600 Uncharacterized Fe-S protein; Fe-S electron transport protein 4683118..4684257 Escherichia coli O104:H4 str. 2009EL-2050 13692362 YP_006772159.1 CDS O3M_22725 NC_018650.1 4685036 4685581 R COG1949 Oligoribonuclease (3'->5' exoribonuclease); oligoribonuclease complement(4685036..4685581) Escherichia coli O104:H4 str. 2009EL-2050 13692366 YP_006772160.1 CDS O3M_22730 NC_018650.1 4685676 4686728 D COG1162 Predicted GTPases; GTPase RsgA 4685676..4686728 Escherichia coli O104:H4 str. 2009EL-2050 13692367 YP_006772161.1 CDS psd NC_018650.1 4686825 4687793 D COG0688 Phosphatidylserine decarboxylase; phosphatidylserine decarboxylase 4686825..4687793 Escherichia coli O104:H4 str. 2009EL-2050 13692368 YP_006772162.1 CDS O3M_22740 NC_018650.1 4687815 4691138 D COG3264 Small-conductance mechanosensitive channel; mechanosensitive channel protein 4687815..4691138 Escherichia coli O104:H4 str. 2009EL-2050 13692369 YP_006772163.1 CDS O3M_22745 NC_018650.1 4691167 4691481 R hypothetical protein complement(4691167..4691481) Escherichia coli O104:H4 str. 2009EL-2050 13692370 YP_006772164.1 CDS O3M_22750 NC_018650.1 4691478 4691792 R hypothetical protein complement(4691478..4691792) Escherichia coli O104:H4 str. 2009EL-2050 13692371 YP_006772165.1 CDS O3M_22755 NC_018650.1 4691844 4693346 R COG0531 Amino acid transporters; inner membrane transporter YjeM complement(4691844..4693346) Escherichia coli O104:H4 str. 2009EL-2050 13692372 YP_006772166.1 CDS O3M_22760 NC_018650.1 4693565 4694542 R COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II); poxB regulator PoxA complement(4693565..4694542) Escherichia coli O104:H4 str. 2009EL-2050 13692373 YP_006772167.1 CDS O3M_22765 NC_018650.1 4694867 4696675 D COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; fumarate reductase flavoprotein subunit 4694867..4696675 Escherichia coli O104:H4 str. 2009EL-2050 13692374 YP_006772168.1 CDS O3M_22770 NC_018650.1 4696668 4697402 D COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; fumarate reductase iron-sulfur subunit 4696668..4697402 Escherichia coli O104:H4 str. 2009EL-2050 13692375 YP_006772169.1 CDS O3M_22775 NC_018650.1 4697413 4697808 D COG3029 Fumarate reductase subunit C; fumarate reductase subunit C 4697413..4697808 Escherichia coli O104:H4 str. 2009EL-2050 13692376 YP_006772170.1 CDS O3M_22780 NC_018650.1 4697819 4698178 D COG3080 Fumarate reductase subunit D; fumarate reductase subunit D 4697819..4698178 Escherichia coli O104:H4 str. 2009EL-2050 13692377 YP_006772171.1 CDS ampC NC_018650.1 4698241 4699374 D COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase/D-alanine carboxypeptidase 4698241..4699374 Escherichia coli O104:H4 str. 2009EL-2050 13692378 YP_006772172.1 CDS O3M_22790 NC_018650.1 4699463 4699996 D COG3040 Bacterial lipocalin; outer membrane lipoprotein Blc 4699463..4699996 Escherichia coli O104:H4 str. 2009EL-2050 13692379 YP_006772173.1 CDS O3M_22795 NC_018650.1 4699993 4700310 R COG2076 Membrane transporters of cations and cationic drugs; suppresser of groEL complement(4699993..4700310) Escherichia coli O104:H4 str. 2009EL-2050 13692380 YP_006772174.1 CDS O3M_22800 NC_018650.1 4700485 4700631 R COG5510 Predicted small secreted protein; entericidin B membrane lipoprotein complement(4700485..4700631) Escherichia coli O104:H4 str. 2009EL-2050 13692381 YP_006772175.1 CDS O3M_22805 NC_018650.1 4700742 4700867 R entericidin A complement(4700742..4700867) Escherichia coli O104:H4 str. 2009EL-2050 13692382 YP_006772176.1 CDS O3M_22810 NC_018650.1 4700919 4701485 R COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); elongation factor P complement(4700919..4701485) Escherichia coli O104:H4 str. 2009EL-2050 13692383 YP_006772177.1 CDS O3M_22815 NC_018650.1 4701527 4702555 D COG1509 Lysine 2,3-aminomutase; lysine aminomutase 4701527..4702555 Escherichia coli O104:H4 str. 2009EL-2050 13692384 YP_006772178.1 CDS O3M_22820 NC_018650.1 4702945 4703814 D COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase); hypothetical protein 4702945..4703814 Escherichia coli O104:H4 str. 2009EL-2050 13692385 YP_006772179.1 CDS O3M_22825 NC_018650.1 4704017 4704370 R hypothetical protein complement(4704017..4704370) Escherichia coli O104:H4 str. 2009EL-2050 13692386 YP_006772180.1 CDS groEL NC_018650.1 4704508 4706154 R COG0459 Chaperonin GroEL (HSP60 family); chaperonin GroEL complement(4704508..4706154) Escherichia coli O104:H4 str. 2009EL-2050 13692387 YP_006772181.1 CDS groES NC_018650.1 4706198 4706491 R COG0234 Co-chaperonin GroES (HSP10); co-chaperonin GroES complement(4706198..4706491) Escherichia coli O104:H4 str. 2009EL-2050 13692388 YP_006772182.1 CDS O3M_22840 NC_018650.1 4706767 4708023 D COG0531 Amino acid transporters; transporter 4706767..4708023 Escherichia coli O104:H4 str. 2009EL-2050 13692389 YP_006772183.1 CDS fxsA NC_018650.1 4708039 4708515 R COG3030 Protein affecting phage T7 exclusion by the F plasmid; phage T7 F exclusion suppressor FxsA complement(4708039..4708515) Escherichia coli O104:H4 str. 2009EL-2050 13692390 YP_006772184.1 CDS aspA NC_018650.1 4708852 4710288 D COG1027 Aspartate ammonia-lyase; aspartate ammonia-lyase 4708852..4710288 Escherichia coli O104:H4 str. 2009EL-2050 13692391 YP_006772185.1 CDS O3M_22855 NC_018650.1 4710406 4711707 D COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 4710406..4711707 Escherichia coli O104:H4 str. 2009EL-2050 13692392 YP_006772186.1 CDS O3M_22860 NC_018650.1 4711823 4712161 D COG1324 Uncharacterized protein involved in tolerance to divalent cations; divalent-cation tolerance protein CutA 4711823..4712161 Escherichia coli O104:H4 str. 2009EL-2050 13692393 YP_006772187.1 CDS dipZ NC_018650.1 4712137 4713834 D COG4232 Thiol:disulfide interchange protein; thiol:disulfide interchange protein 4712137..4713834 Escherichia coli O104:H4 str. 2009EL-2050 13692475 YP_006772188.1 CDS O3M_22870 NC_018650.1 4713871 4714446 D COG1309 Transcriptional regulator; transcriptional regulator 4713871..4714446 Escherichia coli O104:H4 str. 2009EL-2050 13692476 YP_006772189.1 CDS O3M_22875 NC_018650.1 4714826 4716088 D COG0582 Integrase; Prophage integrase 4714826..4716088 Escherichia coli O104:H4 str. 2009EL-2050 13692478 YP_006772190.1 CDS O3M_22890 NC_018650.1 4720418 4720762 D COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 4720418..4720762 Escherichia coli O104:H4 str. 2009EL-2050 13692479 YP_006772191.1 CDS O3M_22900 NC_018650.1 4721091 4721339 R hypothetical protein complement(4721091..4721339) Escherichia coli O104:H4 str. 2009EL-2050 13692480 YP_006772192.1 CDS O3M_22905 NC_018650.1 4721406 4722167 D hypothetical protein 4721406..4722167 Escherichia coli O104:H4 str. 2009EL-2050 13692481 YP_006772193.1 CDS O3M_22910 NC_018650.1 4722528 4726385 D COG3468 Type V secretory pathway, adhesin AidA; Serine protease pet precursor (Plasmid-encoded toxin pet) 4722528..4726385 Escherichia coli O104:H4 str. 2009EL-2050 13692482 YP_006772194.1 CDS O3M_22915 NC_018650.1 4726432 4727013 D hypothetical protein 4726432..4727013 Escherichia coli O104:H4 str. 2009EL-2050 13692483 YP_006772195.1 CDS O3M_22920 NC_018650.1 4727205 4728818 R COG3436 Transposase and inactivated derivatives; transposase complement(4727205..4728818) Escherichia coli O104:H4 str. 2009EL-2050 13692484 YP_006772196.1 CDS O3M_22925 NC_018650.1 4728849 4729199 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(4728849..4729199) Escherichia coli O104:H4 str. 2009EL-2050 13692485 YP_006772197.1 CDS O3M_22930 NC_018650.1 4729196 4729630 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(4729196..4729630) Escherichia coli O104:H4 str. 2009EL-2050 13692486 YP_006772198.1 CDS O3M_22935 NC_018650.1 4729964 4730371 R COG3436 Transposase and inactivated derivatives; protein encoded within IS complement(4729964..4730371) Escherichia coli O104:H4 str. 2009EL-2050 13692487 YP_006772199.1 CDS O3M_22940 NC_018650.1 4730437 4730940 D COG3464 Transposase and inactivated derivatives; transposase 4730437..4730940 Escherichia coli O104:H4 str. 2009EL-2050 13692488 YP_006772200.1 CDS O3M_22950 NC_018650.1 4732169 4732594 D COG2963 Transposase and inactivated derivatives; transposase OrfA from plasmid origin 4732169..4732594 Escherichia coli O104:H4 str. 2009EL-2050 13692489 YP_006772201.1 CDS O3M_22955 NC_018650.1 4732591 4732842 D COG3436 Transposase and inactivated derivatives; IS66 transposase 4732591..4732842 Escherichia coli O104:H4 str. 2009EL-2050 13692490 YP_006772202.1 CDS O3M_22960 NC_018650.1 4732868 4733194 D COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein 4732868..4733194 Escherichia coli O104:H4 str. 2009EL-2050 13692491 YP_006772203.1 CDS O3M_22970 NC_018650.1 4734265 4735788 D COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid 4734265..4735788 Escherichia coli O104:H4 str. 2009EL-2050 13692492 YP_006772204.1 CDS O3M_22980 NC_018650.1 4736753 4738948 R COG1629 Outer membrane receptor proteins, mostly Fe transport; Ferric aerobactin receptor complement(4736753..4738948) Escherichia coli O104:H4 str. 2009EL-2050 13692493 YP_006772205.1 CDS O3M_22985 NC_018650.1 4738954 4740291 R COG3486 Lysine/ornithine N-monooxygenase; L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase) complement(4738954..4740291) Escherichia coli O104:H4 str. 2009EL-2050 13692494 YP_006772206.1 CDS O3M_22990 NC_018650.1 4740288 4742030 R COG4264 Siderophore synthetase component; Aerobactin siderophore biosynthesis protein complement(4740288..4742030) Escherichia coli O104:H4 str. 2009EL-2050 13692495 YP_006772207.1 CDS O3M_22995 NC_018650.1 4742030 4742977 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; siderophore biosynthesis protein complement(4742030..4742977) Escherichia coli O104:H4 str. 2009EL-2050 13692496 YP_006772208.1 CDS O3M_23000 NC_018650.1 4742978 4744759 R COG4264 Siderophore synthetase component; aerobactin siderophore biosynthesis protein complement(4742978..4744759) Escherichia coli O104:H4 str. 2009EL-2050 13692497 YP_006772209.1 CDS O3M_23005 NC_018650.1 4744838 4746031 D COG0477 Permeases of the major facilitator superfamily; membrane transport protein, major facilitator superfamily 4744838..4746031 Escherichia coli O104:H4 str. 2009EL-2050 13692498 YP_006772210.1 CDS O3M_23010 NC_018650.1 4747244 4747411 D hypothetical protein 4747244..4747411 Escherichia coli O104:H4 str. 2009EL-2050 13692499 YP_006772211.1 CDS O3M_23015 NC_018650.1 4747398 4747583 R COG3436 Transposase and inactivated derivatives; transposase complement(4747398..4747583) Escherichia coli O104:H4 str. 2009EL-2050 13692500 YP_006772212.1 CDS O3M_23020 NC_018650.1 4747647 4748789 D COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 4747647..4748789 Escherichia coli O104:H4 str. 2009EL-2050 13692501 YP_006772213.1 CDS O3M_23025 NC_018650.1 4748829 4749719 R COG2801 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORFB, IS629, IS3 family protein complement(4748829..4749719) Escherichia coli O104:H4 str. 2009EL-2050 13692502 YP_006772214.1 CDS O3M_23030 NC_018650.1 4749716 4750042 R COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein complement(4749716..4750042) Escherichia coli O104:H4 str. 2009EL-2050 13692503 YP_006772215.1 CDS O3M_23035 NC_018650.1 4750271 4750555 R COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF1, IS66 family protein complement(4750271..4750555) Escherichia coli O104:H4 str. 2009EL-2050 13692504 YP_006772216.1 CDS O3M_23040 NC_018650.1 4750620 4751744 R COG4584 Transposase and inactivated derivatives; transposase complement(4750620..4751744) Escherichia coli O104:H4 str. 2009EL-2050 13692505 YP_006772217.1 CDS O3M_23045 NC_018650.1 4751965 4752474 D COG3436 Transposase and inactivated derivatives; hypothetical protein 4751965..4752474 Escherichia coli O104:H4 str. 2009EL-2050 13692506 YP_006772218.1 CDS O3M_23050 NC_018650.1 4752537 4752755 D COG3328 Transposase and inactivated derivatives; transposase 4752537..4752755 Escherichia coli O104:H4 str. 2009EL-2050 13692507 YP_006772219.1 CDS O3M_23055 NC_018650.1 4752906 4757024 R COG3468 Type V secretory pathway, adhesin AidA; Serine protease pic precursor (ShMu) complement(4752906..4757024) Escherichia coli O104:H4 str. 2009EL-2050 13692508 YP_006772220.1 CDS O3M_23060 NC_018650.1 4757189 4757560 R COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase complement(4757189..4757560) Escherichia coli O104:H4 str. 2009EL-2050 13692509 YP_006772221.1 CDS O3M_23065 NC_018650.1 4757752 4758933 R COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid complement(4757752..4758933) Escherichia coli O104:H4 str. 2009EL-2050 13692510 YP_006772222.1 CDS O3M_23070 NC_018650.1 4759052 4759276 R CP4-6 prophage (modular protein); COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein complement(4759052..4759276) Escherichia coli O104:H4 str. 2009EL-2050 13692511 YP_006772223.1 CDS O3M_23080 NC_018650.1 4760347 4760673 R COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein complement(4760347..4760673) Escherichia coli O104:H4 str. 2009EL-2050 13692512 YP_006772224.1 CDS O3M_23085 NC_018650.1 4761197 4761670 D antirestriction protein 4761197..4761670 Escherichia coli O104:H4 str. 2009EL-2050 13692513 YP_006772225.1 CDS O3M_23090 NC_018650.1 4761686 4762162 D COG2003 DNA repair proteins; RADC family DNA repair protein 4761686..4762162 Escherichia coli O104:H4 str. 2009EL-2050 13692514 YP_006772226.1 CDS O3M_23095 NC_018650.1 4762249 4762470 D hypothetical protein 4762249..4762470 Escherichia coli O104:H4 str. 2009EL-2050 13692515 YP_006772227.1 CDS O3M_23100 NC_018650.1 4762550 4762927 D CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 4762550..4762927 Escherichia coli O104:H4 str. 2009EL-2050 13692516 YP_006772228.1 CDS O3M_23105 NC_018650.1 4762974 4763351 D hypothetical protein 4762974..4763351 Escherichia coli O104:H4 str. 2009EL-2050 13692517 YP_006772229.1 CDS O3M_23110 NC_018650.1 4763348 4763836 D hypothetical protein 4763348..4763836 Escherichia coli O104:H4 str. 2009EL-2050 13692518 YP_006772230.1 CDS O3M_23115 NC_018650.1 4763856 4764053 D hypothetical protein 4763856..4764053 Escherichia coli O104:H4 str. 2009EL-2050 13692519 YP_006772231.1 CDS O3M_23120 NC_018650.1 4764138 4764980 D hypothetical protein 4764138..4764980 Escherichia coli O104:H4 str. 2009EL-2050 13692520 YP_006772232.1 CDS O3M_23125 NC_018650.1 4765729 4767267 D COG3710 DNA-binding winged-HTH domains; DNA-binding transcriptional activator CadC 4765729..4767267 Escherichia coli O104:H4 str. 2009EL-2050 13692521 YP_006772233.1 CDS cadB NC_018650.1 4767633 4768967 D COG0531 Amino acid transporters; lysine/cadaverine antiporter 4767633..4768967 Escherichia coli O104:H4 str. 2009EL-2050 13692522 YP_006772234.1 CDS O3M_23135 NC_018650.1 4769047 4771194 D COG1982 Arginine/lysine/ornithine decarboxylases; lysine decarboxylase CadA 4769047..4771194 Escherichia coli O104:H4 str. 2009EL-2050 13692523 YP_006772235.1 CDS O3M_23140 NC_018650.1 4771253 4772710 D COG3104 Dipeptide/tripeptide permease; transporter 4771253..4772710 Escherichia coli O104:H4 str. 2009EL-2050 13692524 YP_006772236.1 CDS O3M_23145 NC_018650.1 4772947 4774464 D COG1190 Lysyl-tRNA synthetase (class II); lysyl-tRNA synthetase 4772947..4774464 Escherichia coli O104:H4 str. 2009EL-2050 13692525 YP_006772237.1 CDS O3M_23150 NC_018650.1 4774583 4774756 R hypothetical protein complement(4774583..4774756) Escherichia coli O104:H4 str. 2009EL-2050 13692526 YP_006772238.1 CDS O3M_23155 NC_018650.1 4774784 4775080 R hypothetical protein complement(4774784..4775080) Escherichia coli O104:H4 str. 2009EL-2050 13692527 YP_006772239.1 CDS O3M_23160 NC_018650.1 4775307 4775579 R COG2388 Predicted acetyltransferase; acyltransferase complement(4775307..4775579) Escherichia coli O104:H4 str. 2009EL-2050 13692528 YP_006772240.1 CDS O3M_23165 NC_018650.1 4775591 4775821 R COG3592 Uncharacterized conserved protein; hypothetical protein complement(4775591..4775821) Escherichia coli O104:H4 str. 2009EL-2050 13692529 YP_006772241.1 CDS O3M_23170 NC_018650.1 4776002 4777633 D COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; sensory histidine kinase DcuS 4776002..4777633 Escherichia coli O104:H4 str. 2009EL-2050 13692530 YP_006772242.1 CDS O3M_23175 NC_018650.1 4777630 4778349 D COG4565 Response regulator of citrate/malate metabolism; DNA-binding transcriptional activator DcuR 4777630..4778349 Escherichia coli O104:H4 str. 2009EL-2050 13692531 YP_006772243.1 CDS O3M_23180 NC_018650.1 4778920 4780260 D COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 4778920..4780260 Escherichia coli O104:H4 str. 2009EL-2050 13692532 YP_006772244.1 CDS O3M_23185 NC_018650.1 4780338 4781984 D COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase FumB 4780338..4781984 Escherichia coli O104:H4 str. 2009EL-2050 13692533 YP_006772245.1 CDS O3M_23190 NC_018650.1 4782107 4782736 D COG3647 Predicted membrane protein; hypothetical protein 4782107..4782736 Escherichia coli O104:H4 str. 2009EL-2050 13692534 YP_006772246.1 CDS O3M_23195 NC_018650.1 4782875 4784284 R COG2211 Na+/melibiose symporter and related transporters; melibiose:sodium symporter complement(4782875..4784284) Escherichia coli O104:H4 str. 2009EL-2050 13692535 YP_006772247.1 CDS O3M_23200 NC_018650.1 4784399 4785754 R COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; alpha-galactosidase complement(4784399..4785754) Escherichia coli O104:H4 str. 2009EL-2050 13692536 YP_006772248.1 CDS O3M_23205 NC_018650.1 4786037 4786945 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator MelR 4786037..4786945 Escherichia coli O104:H4 str. 2009EL-2050 13692537 YP_006772249.1 CDS O3M_23210 NC_018650.1 4787141 4789411 D COG1982 Arginine/lysine/ornithine decarboxylases; arginine decarboxylase 4787141..4789411 Escherichia coli O104:H4 str. 2009EL-2050 13692538 YP_006772250.1 CDS O3M_23215 NC_018650.1 4789736 4790497 D COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 4789736..4790497 Escherichia coli O104:H4 str. 2009EL-2050 13692539 YP_006772251.1 CDS O3M_23220 NC_018650.1 4790634 4791971 D COG0531 Amino acid transporters; arginine:agmatin antiporter 4790634..4791971 Escherichia coli O104:H4 str. 2009EL-2050 13692540 YP_006772252.1 CDS O3M_23225 NC_018650.1 4792075 4793718 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; metal dependent hydrolase 4792075..4793718 Escherichia coli O104:H4 str. 2009EL-2050 13692541 YP_006772253.1 CDS O3M_23230 NC_018650.1 4793715 4794383 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator BasR 4793715..4794383 Escherichia coli O104:H4 str. 2009EL-2050 13692542 YP_006772254.1 CDS O3M_23235 NC_018650.1 4794393 4795484 D COG0642 Signal transduction histidine kinase; sensor protein BasS/PmrB 4794393..4795484 Escherichia coli O104:H4 str. 2009EL-2050 13692543 YP_006772255.1 CDS O3M_23240 NC_018650.1 4795661 4797163 R COG0477 Permeases of the major facilitator superfamily; proline/glycine betaine transporter complement(4795661..4797163) Escherichia coli O104:H4 str. 2009EL-2050 13692544 YP_006772256.1 CDS O3M_23245 NC_018650.1 4797427 4798305 R hypothetical protein complement(4797427..4798305) Escherichia coli O104:H4 str. 2009EL-2050 13692545 YP_006772257.1 CDS O3M_23250 NC_018650.1 4798302 4800530 R COG0699 Predicted GTPases (dynamin-related); hypothetical protein complement(4798302..4800530) Escherichia coli O104:H4 str. 2009EL-2050 13692546 YP_006772258.1 CDS O3M_23255 NC_018650.1 4800932 4801267 D COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; alkylphosphonate uptake protein in phosphonate metabolism 4800932..4801267 Escherichia coli O104:H4 str. 2009EL-2050 13692547 YP_006772259.1 CDS O3M_23260 NC_018650.1 4801427 4801870 D COG2764 Uncharacterized protein conserved in bacteria; hypothetical protein 4801427..4801870 Escherichia coli O104:H4 str. 2009EL-2050 13692548 YP_006772260.1 CDS O3M_23265 NC_018650.1 4802003 4802791 D COG3638 ABC-type phosphate/phosphonate transport system, ATPase component; phosphonate/organophosphate ester transporter subunit 4802003..4802791 Escherichia coli O104:H4 str. 2009EL-2050 13692549 YP_006772261.1 CDS O3M_23270 NC_018650.1 4802816 4803832 D COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component; phosphonate/organophosphate ester transporter subunit PhnD 4802816..4803832 Escherichia coli O104:H4 str. 2009EL-2050 13692550 YP_006772262.1 CDS O3M_23275 NC_018650.1 4803938 4804717 D COG3639 ABC-type phosphate/phosphonate transport system, permease component; Pn transporter membrane channel protein 4803938..4804717 Escherichia coli O104:H4 str. 2009EL-2050 13692551 YP_006772263.1 CDS O3M_23280 NC_018650.1 4804738 4805463 D COG2188 Transcriptional regulators; phosphonate metabolism transcriptional regulator PhnF 4804738..4805463 Escherichia coli O104:H4 str. 2009EL-2050 13692552 YP_006772264.1 CDS O3M_23285 NC_018650.1 4805464 4805916 D COG3624 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4805464..4805916 Escherichia coli O104:H4 str. 2009EL-2050 13692553 YP_006772265.1 CDS phnH NC_018650.1 4805913 4806497 D COG3625 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4805913..4806497 Escherichia coli O104:H4 str. 2009EL-2050 13692554 YP_006772266.1 CDS O3M_23295 NC_018650.1 4806497 4807561 D COG3626 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4806497..4807561 Escherichia coli O104:H4 str. 2009EL-2050 13692555 YP_006772267.1 CDS O3M_23300 NC_018650.1 4807554 4808399 D COG3627 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit PhnJ 4807554..4808399 Escherichia coli O104:H4 str. 2009EL-2050 13692637 YP_006772268.1 CDS phnK NC_018650.1 4808396 4809154 D COG4107 ABC-type phosphonate transport system, ATPase component; phosphonate C-P lyase system protein PhnK 4808396..4809154 Escherichia coli O104:H4 str. 2009EL-2050 13692638 YP_006772269.1 CDS O3M_23310 NC_018650.1 4809331 4810011 D COG4778 ABC-type phosphonate transport system, ATPase component; carbon-phosphorus lyase complex subunit PhnL 4809331..4810011 Escherichia coli O104:H4 str. 2009EL-2050 13692639 YP_006772270.1 CDS O3M_23315 NC_018650.1 4810008 4811144 D COG3454 Metal-dependent hydrolase involved in phosphonate metabolism; phosphonate metabolism protein PhnM 4810008..4811144 Escherichia coli O104:H4 str. 2009EL-2050 13692640 YP_006772271.1 CDS O3M_23320 NC_018650.1 4811144 4811701 D COG3709 Uncharacterized component of phosphonate metabolism; ribose 1,5-bisphosphokinase 4811144..4811701 Escherichia coli O104:H4 str. 2009EL-2050 13692641 YP_006772272.1 CDS O3M_23325 NC_018650.1 4811688 4812122 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; aminoalkylphosphonic acid N-acetyltransferase 4811688..4812122 Escherichia coli O104:H4 str. 2009EL-2050 13692642 YP_006772273.1 CDS phnP NC_018650.1 4812124 4812882 D COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; carbon-phosphorus lyase complex accessory protein 4812124..4812882 Escherichia coli O104:H4 str. 2009EL-2050 13692643 YP_006772274.1 CDS O3M_23335 NC_018650.1 4813029 4813358 R hypothetical protein complement(4813029..4813358) Escherichia coli O104:H4 str. 2009EL-2050 13692644 YP_006772275.1 CDS O3M_23340 NC_018650.1 4813427 4813744 R COG0698 Ribose 5-phosphate isomerase RpiB; hypothetical protein complement(4813427..4813744) Escherichia coli O104:H4 str. 2009EL-2050 13692645 YP_006772276.1 CDS O3M_23345 NC_018650.1 4813997 4815982 D COG2015 Alkyl sulfatase and related hydrolases; hypothetical protein 4813997..4815982 Escherichia coli O104:H4 str. 2009EL-2050 13692646 YP_006772277.1 CDS O3M_23350 NC_018650.1 4816191 4816466 D formate dehydrogenase H 4816191..4816466 Escherichia coli O104:H4 str. 2009EL-2050 13692647 YP_006772278.1 CDS O3M_23355 NC_018650.1 4816485 4817516 D COG1566 Multidrug resistance efflux pump; multidrug resistance protein MdtN 4816485..4817516 Escherichia coli O104:H4 str. 2009EL-2050 13692648 YP_006772279.1 CDS O3M_23360 NC_018650.1 4817516 4819567 D COG1289 Predicted membrane protein; multidrug efflux system protein MdtO 4817516..4819567 Escherichia coli O104:H4 str. 2009EL-2050 13692649 YP_006772280.1 CDS O3M_23365 NC_018650.1 4819564 4821030 D COG1538 Outer membrane protein; outer membrane efflux protein MdtP 4819564..4821030 Escherichia coli O104:H4 str. 2009EL-2050 13692650 YP_006772281.1 CDS O3M_23370 NC_018650.1 4821228 4821647 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-H, selenopolypeptide subunit 4821228..4821647 Escherichia coli O104:H4 str. 2009EL-2050 13692651 YP_006772282.1 CDS O3M_23375 NC_018650.1 4821696 4823375 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-H, selenopolypeptide subunit 4821696..4823375 Escherichia coli O104:H4 str. 2009EL-2050 13692652 YP_006772283.1 CDS O3M_23380 NC_018650.1 4823469 4824158 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 4823469..4824158 Escherichia coli O104:H4 str. 2009EL-2050 13692653 YP_006772284.1 CDS gltP NC_018650.1 4824236 4825549 R COG1301 Na+/H+-dicarboxylate symporters; glutamate/aspartate:proton symporter complement(4824236..4825549) Escherichia coli O104:H4 str. 2009EL-2050 13692654 YP_006772285.1 CDS O3M_23390 NC_018650.1 4825891 4826487 R COG4235 Cytochrome c biogenesis factor; formate-dependent nitrite reductase complex subunit NrfG complement(4825891..4826487) Escherichia coli O104:H4 str. 2009EL-2050 13692655 YP_006772286.1 CDS O3M_23395 NC_018650.1 4826484 4826867 R COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; formate-dependent nitrite reductase complex subunit NrfF complement(4826484..4826867) Escherichia coli O104:H4 str. 2009EL-2050 13692656 YP_006772287.1 CDS O3M_23400 NC_018650.1 4826860 4828518 R COG1138 Cytochrome c biogenesis factor; heme lyase subunit NrfE complement(4826860..4828518) Escherichia coli O104:H4 str. 2009EL-2050 13692657 YP_006772288.1 CDS O3M_23405 NC_018650.1 4828598 4829554 R COG3301 Formate-dependent nitrite reductase, membrane component; formate-dependent nitrite reductase, membrane subunit complement(4828598..4829554) Escherichia coli O104:H4 str. 2009EL-2050 13692658 YP_006772289.1 CDS O3M_23410 NC_018650.1 4829551 4830222 R Fe-S center; COG0437 Fe-S-cluster-containing hydrogenase components 1; formate-dependent nitrite reductase complement(4829551..4830222) Escherichia coli O104:H4 str. 2009EL-2050 13692659 YP_006772290.1 CDS O3M_23415 NC_018650.1 4830219 4830785 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; cytochrome c nitrite reductase pentaheme subunit complement(4830219..4830785) Escherichia coli O104:H4 str. 2009EL-2050 13692660 YP_006772291.1 CDS nrfA NC_018650.1 4830830 4832266 R COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit; cytochrome c nitrite reductase subunit c552 complement(4830830..4832266) Escherichia coli O104:H4 str. 2009EL-2050 13692661 YP_006772292.1 CDS O3M_23425 NC_018650.1 4832658 4834616 D COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; acetyl-CoA synthetase 4832658..4834616 Escherichia coli O104:H4 str. 2009EL-2050 13692662 YP_006772293.1 CDS O3M_23430 NC_018650.1 4834816 4835130 D COG3162 Predicted membrane protein; hypothetical protein 4834816..4835130 Escherichia coli O104:H4 str. 2009EL-2050 13692663 YP_006772294.1 CDS actP NC_018650.1 4835127 4836776 D COG4147 Predicted symporter; acetate permease 4835127..4836776 Escherichia coli O104:H4 str. 2009EL-2050 13692664 YP_006772295.1 CDS O3M_23440 NC_018650.1 4836954 4838246 D COG1357 Uncharacterized low-complexity proteins; hypothetical protein 4836954..4838246 Escherichia coli O104:H4 str. 2009EL-2050 13692665 YP_006772296.1 CDS O3M_23445 NC_018650.1 4838400 4840049 R COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; cation/proton antiporter complement(4838400..4840049) Escherichia coli O104:H4 str. 2009EL-2050 13692666 YP_006772297.1 CDS O3M_23450 NC_018650.1 4840200 4841549 R COG2252 Permeases; permease complement(4840200..4841549) Escherichia coli O104:H4 str. 2009EL-2050 13692667 YP_006772298.1 CDS O3M_23455 NC_018650.1 4842095 4842559 R COG0789 Predicted transcriptional regulators; redox-sensitivie transcriptional activator Soxr complement(4842095..4842559) Escherichia coli O104:H4 str. 2009EL-2050 13692668 YP_006772299.1 CDS O3M_23460 NC_018650.1 4842645 4842968 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator SoxS 4842645..4842968 Escherichia coli O104:H4 str. 2009EL-2050 13692669 YP_006772300.1 CDS O3M_23465 NC_018650.1 4842971 4844557 R COG4943 Predicted signal transduction protein containing sensor and EAL domains; signal transduction protein (EAL domain containing protein) complement(4842971..4844557) Escherichia coli O104:H4 str. 2009EL-2050 13692670 YP_006772301.1 CDS O3M_23470 NC_018650.1 4844987 4845268 D hypothetical protein 4844987..4845268 Escherichia coli O104:H4 str. 2009EL-2050 13692671 YP_006772302.1 CDS O3M_23475 NC_018650.1 4845367 4845903 R COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein complement(4845367..4845903) Escherichia coli O104:H4 str. 2009EL-2050 13692672 YP_006772303.1 CDS uvrA NC_018650.1 4846157 4848979 D COG0178 Excinuclease ATPase subunit; excinuclease ABC subunit A 4846157..4848979 Escherichia coli O104:H4 str. 2009EL-2050 13692673 YP_006772304.1 CDS O3M_23485 NC_018650.1 4849014 4849370 R COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4849014..4849370) Escherichia coli O104:H4 str. 2009EL-2050 13692674 YP_006772305.1 CDS O3M_23490 NC_018650.1 4849374 4849790 R COG0432 Uncharacterized conserved protein; hypothetical protein complement(4849374..4849790) Escherichia coli O104:H4 str. 2009EL-2050 13692675 YP_006772306.1 CDS aphA NC_018650.1 4849901 4850614 R COG3700 Acid phosphatase (class B); acid phosphatase/phosphotransferase complement(4849901..4850614) Escherichia coli O104:H4 str. 2009EL-2050 13692676 YP_006772307.1 CDS O3M_23500 NC_018650.1 4851016 4851519 D hypothetical protein 4851016..4851519 Escherichia coli O104:H4 str. 2009EL-2050 13692677 YP_006772308.1 CDS O3M_23505 NC_018650.1 4851741 4852934 R COG1448 Aspartate/tyrosine/aromatic aminotransferase; aromatic amino acid aminotransferase complement(4851741..4852934) Escherichia coli O104:H4 str. 2009EL-2050 13692678 YP_006772309.1 CDS alr NC_018650.1 4853187 4854266 R COG0787 Alanine racemase; alanine racemase complement(4853187..4854266) Escherichia coli O104:H4 str. 2009EL-2050 13692679 YP_006772310.1 CDS O3M_23515 NC_018650.1 4854319 4855734 R COG0305 Replicative DNA helicase; replicative DNA helicase complement(4854319..4855734) Escherichia coli O104:H4 str. 2009EL-2050 13692680 YP_006772311.1 CDS O3M_23520 NC_018650.1 4855817 4856800 D COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; quinone oxidoreductase 4855817..4856800 Escherichia coli O104:H4 str. 2009EL-2050 13692681 YP_006772312.1 CDS pspG NC_018650.1 4856966 4857208 R phage shock protein G complement(4856966..4857208) Escherichia coli O104:H4 str. 2009EL-2050 13692682 YP_006772313.1 CDS O3M_23530 NC_018650.1 4857342 4858361 R COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase A complement(4857342..4858361) Escherichia coli O104:H4 str. 2009EL-2050 13692683 YP_006772314.1 CDS O3M_23535 NC_018650.1 4858743 4859456 R hypothetical protein complement(4858743..4859456) Escherichia coli O104:H4 str. 2009EL-2050 13692684 YP_006772315.1 CDS O3M_23540 NC_018650.1 4859480 4859734 R hypothetical protein complement(4859480..4859734) Escherichia coli O104:H4 str. 2009EL-2050 13692685 YP_006772316.1 CDS O3M_23545 NC_018650.1 4860052 4860567 D COG0735 Fe2+/Zn2+ uptake regulation proteins; zinc uptake transcriptional repressor 4860052..4860567 Escherichia coli O104:H4 str. 2009EL-2050 13692686 YP_006772317.1 CDS O3M_23550 NC_018650.1 4860609 4860818 R COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4860609..4860818) Escherichia coli O104:H4 str. 2009EL-2050 13692687 YP_006772318.1 CDS O3M_23555 NC_018650.1 4860914 4862260 R COG0534 Na+-driven multidrug efflux pump; DNA-damage-inducible SOS response protein complement(4860914..4862260) Escherichia coli O104:H4 str. 2009EL-2050 13692688 YP_006772319.1 CDS O3M_23560 NC_018650.1 4862333 4862941 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); LexA repressor complement(4862333..4862941) Escherichia coli O104:H4 str. 2009EL-2050 13692689 YP_006772320.1 CDS O3M_23565 NC_018650.1 4863051 4863419 R COG0818 Diacylglycerol kinase; diacylglycerol kinase complement(4863051..4863419) Escherichia coli O104:H4 str. 2009EL-2050 13692690 YP_006772321.1 CDS O3M_23570 NC_018650.1 4863590 4866013 D COG2937 Glycerol-3-phosphate O-acyltransferase; glycerol-3-phosphate acyltransferase 4863590..4866013 Escherichia coli O104:H4 str. 2009EL-2050 13692691 YP_006772322.1 CDS ubiA NC_018650.1 4866168 4867040 R COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; 4-hydroxybenzoate octaprenyltransferase complement(4866168..4867040) Escherichia coli O104:H4 str. 2009EL-2050 13692692 YP_006772323.1 CDS ubiC NC_018650.1 4867053 4867550 R COG3161 4-hydroxybenzoate synthetase (chorismate lyase); chorismate pyruvate lyase complement(4867053..4867550) Escherichia coli O104:H4 str. 2009EL-2050 13692693 YP_006772324.1 CDS O3M_23585 NC_018650.1 4867773 4869101 R COG1357 Uncharacterized low-complexity proteins; hypothetical protein complement(4867773..4869101) Escherichia coli O104:H4 str. 2009EL-2050 13692694 YP_006772325.1 CDS O3M_23590 NC_018650.1 4869159 4869353 R hypothetical protein complement(4869159..4869353) Escherichia coli O104:H4 str. 2009EL-2050 13692695 YP_006772326.1 CDS O3M_23595 NC_018650.1 4869582 4870502 R maltose regulon periplasmic protein complement(4869582..4870502) Escherichia coli O104:H4 str. 2009EL-2050 13692696 YP_006772327.1 CDS lamB NC_018650.1 4870654 4871994 R COG4580 Maltoporin (phage lambda and maltose receptor); maltoporin complement(4870654..4871994) Escherichia coli O104:H4 str. 2009EL-2050 13692697 YP_006772328.1 CDS O3M_23605 NC_018650.1 4872066 4873181 R COG3839 ABC-type sugar transport systems, ATPase components; maltose/maltodextrin transporter ATP-binding protein complement(4872066..4873181) Escherichia coli O104:H4 str. 2009EL-2050 13692698 YP_006772329.1 CDS O3M_23610 NC_018650.1 4873358 4873453 D hypothetical protein 4873358..4873453 Escherichia coli O104:H4 str. 2009EL-2050 13692699 YP_006772330.1 CDS malE NC_018650.1 4873546 4874736 D COG2182 Maltose-binding periplasmic proteins/domains; maltose ABC transporter substrate-binding protein 4873546..4874736 Escherichia coli O104:H4 str. 2009EL-2050 13692700 YP_006772331.1 CDS malF NC_018650.1 4874890 4876434 D COG1175 ABC-type sugar transport systems, permease components; maltose transporter membrane protein 4874890..4876434 Escherichia coli O104:H4 str. 2009EL-2050 13692701 YP_006772332.1 CDS malG NC_018650.1 4876449 4877339 D COG3833 ABC-type maltose transport systems, permease component; maltose transporter permease 4876449..4877339 Escherichia coli O104:H4 str. 2009EL-2050 13692702 YP_006772333.1 CDS xylE NC_018650.1 4877711 4879186 D COG0477 Permeases of the major facilitator superfamily; D-xylose transporter XylE 4877711..4879186 Escherichia coli O104:H4 str. 2009EL-2050 13692703 YP_006772334.1 CDS O3M_23635 NC_018650.1 4879230 4879640 R COG3223 Predicted membrane protein; phosphate-starvation-inducible protein PsiE complement(4879230..4879640) Escherichia coli O104:H4 str. 2009EL-2050 13692704 YP_006772335.1 CDS O3M_23640 NC_018650.1 4879766 4879909 R hypothetical protein complement(4879766..4879909) Escherichia coli O104:H4 str. 2009EL-2050 13692705 YP_006772336.1 CDS O3M_23645 NC_018650.1 4880235 4882331 R porin complement(4880235..4882331) Escherichia coli O104:H4 str. 2009EL-2050 13692706 YP_006772337.1 CDS O3M_23650 NC_018650.1 4882331 4883068 R hypothetical protein complement(4882331..4883068) Escherichia coli O104:H4 str. 2009EL-2050 13692707 YP_006772338.1 CDS O3M_23655 NC_018650.1 4883065 4883703 R hypothetical protein complement(4883065..4883703) Escherichia coli O104:H4 str. 2009EL-2050 13692708 YP_006772339.1 CDS pgi NC_018650.1 4884414 4886063 R COG0166 Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase complement(4884414..4886063) Escherichia coli O104:H4 str. 2009EL-2050 13692709 YP_006772340.1 CDS O3M_23665 NC_018650.1 4886588 4887937 D COG0527 Aspartokinases; aspartate kinase III 4886588..4887937 Escherichia coli O104:H4 str. 2009EL-2050 13692710 YP_006772341.1 CDS O3M_23670 NC_018650.1 4888082 4889008 D COG0464 ATPases of the AAA+ class; hypothetical protein 4888082..4889008 Escherichia coli O104:H4 str. 2009EL-2050 13692711 YP_006772342.1 CDS O3M_23675 NC_018650.1 4889044 4889808 R COG3541 Predicted nucleotidyltransferase; hypothetical protein complement(4889044..4889808) Escherichia coli O104:H4 str. 2009EL-2050 13692712 YP_006772343.1 CDS O3M_23680 NC_018650.1 4889841 4890968 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein complement(4889841..4890968) Escherichia coli O104:H4 str. 2009EL-2050 13692713 YP_006772344.1 CDS O3M_23685 NC_018650.1 4891497 4891769 D hypothetical protein 4891497..4891769 Escherichia coli O104:H4 str. 2009EL-2050 13692714 YP_006772345.1 CDS O3M_23690 NC_018650.1 4891770 4892642 R COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridine synthase F complement(4891770..4892642) Escherichia coli O104:H4 str. 2009EL-2050 13692715 YP_006772346.1 CDS O3M_23695 NC_018650.1 4892854 4893543 D COG3340 Peptidase E; (alpha)-aspartyl dipeptidase 4892854..4893543 Escherichia coli O104:H4 str. 2009EL-2050 13692716 YP_006772347.1 CDS O3M_23700 NC_018650.1 4893634 4895265 R COG1283 Na+/phosphate symporter; transporter complement(4893634..4895265) Escherichia coli O104:H4 str. 2009EL-2050 13692717 YP_006772348.1 CDS metH NC_018650.1 4895485 4899168 R COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain; B12-dependent methionine synthase complement(4895485..4899168) Escherichia coli O104:H4 str. 2009EL-2050 13692718 YP_006772349.1 CDS O3M_23710 NC_018650.1 4899368 4900192 D COG1414 Transcriptional regulator; IclR family transcriptional regulator 4899368..4900192 Escherichia coli O104:H4 str. 2009EL-2050 13692719 YP_006772350.1 CDS O3M_23715 NC_018650.1 4900509 4902083 D ShET2 enterotoxin domain-containing protein 4900509..4902083 Escherichia coli O104:H4 str. 2009EL-2050 13692720 YP_006772351.1 CDS aceK NC_018650.1 4902052 4903788 R COG4579 Isocitrate dehydrogenase kinase/phosphatase; bifunctional isocitrate dehydrogenase kinase/phosphatase complement(4902052..4903788) Escherichia coli O104:H4 str. 2009EL-2050 13692721 YP_006772352.1 CDS O3M_23725 NC_018650.1 4904069 4905373 R COG2224 Isocitrate lyase; isocitrate lyase complement(4904069..4905373) Escherichia coli O104:H4 str. 2009EL-2050 13692722 YP_006772353.1 CDS O3M_23730 NC_018650.1 4905403 4907004 R COG2225 Malate synthase; malate synthase complement(4905403..4907004) Escherichia coli O104:H4 str. 2009EL-2050 13692723 YP_006772354.1 CDS O3M_23735 NC_018650.1 4907273 4908202 R COG1897 Homoserine trans-succinylase; homoserine O-succinyltransferase complement(4907273..4908202) Escherichia coli O104:H4 str. 2009EL-2050 13692724 YP_006772355.1 CDS O3M_23740 NC_018650.1 4908359 4908802 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 4908359..4908802 Escherichia coli O104:H4 str. 2009EL-2050 13692725 YP_006772356.1 CDS purH NC_018650.1 4914553 4916142 D COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4914553..4916142 Escherichia coli O104:H4 str. 2009EL-2050 13692730 YP_006772357.1 CDS O3M_23750 NC_018650.1 4916154 4917443 D COG0151 Phosphoribosylamine-glycine ligase; phosphoribosylamine--glycine ligase 4916154..4917443 Escherichia coli O104:H4 str. 2009EL-2050 13692731 YP_006772358.1 CDS O3M_23755 NC_018650.1 4917440 4918765 R COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; transcriptional regulatory protein ZraR complement(4917440..4918765) Escherichia coli O104:H4 str. 2009EL-2050 13692732 YP_006772359.1 CDS O3M_23760 NC_018650.1 4918762 4920138 R COG0642 Signal transduction histidine kinase; sensor protein ZraS complement(4918762..4920138) Escherichia coli O104:H4 str. 2009EL-2050 13692733 YP_006772360.1 CDS zraP NC_018650.1 4920376 4920801 D COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; zinc resistance protein 4920376..4920801 Escherichia coli O104:H4 str. 2009EL-2050 13692734 YP_006772361.1 CDS O3M_23770 NC_018650.1 4920803 4921498 R hypothetical protein complement(4920803..4921498) Escherichia coli O104:H4 str. 2009EL-2050 13692735 YP_006772362.1 CDS O3M_23775 NC_018650.1 4921511 4921783 R COG0776 Bacterial nucleoid DNA-binding protein; transcriptional regulator HU subunit alpha complement(4921511..4921783) Escherichia coli O104:H4 str. 2009EL-2050 13692736 YP_006772363.1 CDS O3M_23780 NC_018650.1 4921970 4922560 R COG3068 Uncharacterized protein conserved in bacteria; hypothetical protein complement(4921970..4922560) Escherichia coli O104:H4 str. 2009EL-2050 13692737 YP_006772364.1 CDS O3M_23785 NC_018650.1 4922603 4923274 R COG1515 Deoxyinosine 3'endonuclease (endonuclease V); endonuclease V complement(4922603..4923274) Escherichia coli O104:H4 str. 2009EL-2050 13692738 YP_006772365.1 CDS hemE NC_018650.1 4923284 4924348 R COG0407 Uroporphyrinogen-III decarboxylase; uroporphyrinogen decarboxylase complement(4923284..4924348) Escherichia coli O104:H4 str. 2009EL-2050 13692739 YP_006772366.1 CDS nudC NC_018650.1 4924388 4925161 R COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; NADH pyrophosphatase complement(4924388..4925161) Escherichia coli O104:H4 str. 2009EL-2050 13692740 YP_006772367.1 CDS O3M_23800 NC_018650.1 4925256 4925732 D COG3160 Regulator of sigma D; anti-RNA polymerase sigma 70 factor 4925256..4925732 Escherichia coli O104:H4 str. 2009EL-2050 13692741 YP_006772368.1 CDS O3M_23805 NC_018650.1 4925965 4927860 D COG0422 Thiamine biosynthesis protein ThiC; thiamine biosynthesis protein ThiC 4925965..4927860 Escherichia coli O104:H4 str. 2009EL-2050 13692742 YP_006772369.1 CDS O3M_23810 NC_018650.1 4927860 4928495 D COG0352 Thiamine monophosphate synthase; thiamine-phosphate pyrophosphorylase 4927860..4928495 Escherichia coli O104:H4 str. 2009EL-2050 13692743 YP_006772370.1 CDS O3M_23815 NC_018650.1 4928488 4929243 D COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; thiamin biosynthesis protein ThiF 4928488..4929243 Escherichia coli O104:H4 str. 2009EL-2050 13692744 YP_006772371.1 CDS O3M_23820 NC_018650.1 4929227 4929427 D COG2104 Sulfur transfer protein involved in thiamine biosynthesis; sulfur carrier protein ThiS 4929227..4929427 Escherichia coli O104:H4 str. 2009EL-2050 13692745 YP_006772372.1 CDS thiG NC_018650.1 4929429 4930199 D COG2022 Uncharacterized enzyme of thiazole biosynthesis; thiazole synthase 4929429..4930199 Escherichia coli O104:H4 str. 2009EL-2050 13692746 YP_006772373.1 CDS thiH NC_018650.1 4930196 4931329 D COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; thiamine biosynthesis protein ThiH 4930196..4931329 Escherichia coli O104:H4 str. 2009EL-2050 13692747 YP_006772374.1 CDS O3M_23835 NC_018650.1 4931739 4932278 R stationary phase growth adaptation protein complement(4931739..4932278) Escherichia coli O104:H4 str. 2009EL-2050 13692748 YP_006772375.1 CDS O3M_23840 NC_018650.1 4932491 4936714 R COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' complement(4932491..4936714) Escherichia coli O104:H4 str. 2009EL-2050 13692749 YP_006772376.1 CDS rpoB NC_018650.1 4936791 4940819 R COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-directed RNA polymerase subunit beta complement(4936791..4940819) Escherichia coli O104:H4 str. 2009EL-2050 13692750 YP_006772377.1 CDS rplL NC_018650.1 4941139 4941504 R COG0222 Ribosomal protein L7/L12; 50S ribosomal protein L7/L12 complement(4941139..4941504) Escherichia coli O104:H4 str. 2009EL-2050 13692751 YP_006772378.1 CDS rplJ NC_018650.1 4941571 4942068 R COG0244 Ribosomal protein L10; 50S ribosomal protein L10 complement(4941571..4942068) Escherichia coli O104:H4 str. 2009EL-2050 13692752 YP_006772379.1 CDS rplA NC_018650.1 4942481 4943185 R COG0081 Ribosomal protein L1; 50S ribosomal protein L1 complement(4942481..4943185) Escherichia coli O104:H4 str. 2009EL-2050 13692753 YP_006772380.1 CDS rplK NC_018650.1 4943189 4943617 R COG0080 Ribosomal protein L11; 50S ribosomal protein L11 complement(4943189..4943617) Escherichia coli O104:H4 str. 2009EL-2050 13692754 YP_006772381.1 CDS nusG NC_018650.1 4943776 4944321 R COG0250 Transcription antiterminator; transcription antitermination protein NusG complement(4943776..4944321) Escherichia coli O104:H4 str. 2009EL-2050 13692755 YP_006772382.1 CDS secE NC_018650.1 4944323 4944706 R COG0690 Preprotein translocase subunit SecE; preprotein translocase subunit SecE complement(4944323..4944706) Escherichia coli O104:H4 str. 2009EL-2050 13692756 YP_006772383.1 CDS O3M_23880 NC_018650.1 4944936 4946120 R COG0050 GTPases - translation elongation factors; elongation factor Tu complement(4944936..4946120) Escherichia coli O104:H4 str. 2009EL-2050 13692757 YP_006772384.1 CDS O3M_23890 NC_018650.1 4947038 4947988 D COG1072 Panthothenate kinase; pantothenate kinase 4947038..4947988 Escherichia coli O104:H4 str. 2009EL-2050 13692762 YP_006772385.1 CDS O3M_23895 NC_018650.1 4948017 4948982 R COG1654 Biotin operon repressor; bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor complement(4948017..4948982) Escherichia coli O104:H4 str. 2009EL-2050 13692763 YP_006772386.1 CDS murB NC_018650.1 4948979 4950007 R COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylenolpyruvoylglucosamine reductase complement(4948979..4950007) Escherichia coli O104:H4 str. 2009EL-2050 13692764 YP_006772387.1 CDS O3M_23905 NC_018650.1 4955779 4956636 R COG0796 Glutamate racemase; glutamate racemase complement(4955779..4956636) Escherichia coli O104:H4 str. 2009EL-2050 13692769 YP_006772388.1 CDS btuB NC_018650.1 4956581 4958425 R COG4206 Outer membrane cobalamin receptor protein; vitamin B12/cobalamin outer membrane transporter complement(4956581..4958425) Escherichia coli O104:H4 str. 2009EL-2050 13692770 YP_006772389.1 CDS O3M_23915 NC_018650.1 4958794 4959894 D COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; tRNA (uracil-5-)-methyltransferase 4958794..4959894 Escherichia coli O104:H4 str. 2009EL-2050 13692771 YP_006772390.1 CDS O3M_23920 NC_018650.1 4959934 4960293 R hypothetical protein complement(4959934..4960293) Escherichia coli O104:H4 str. 2009EL-2050 13692772 YP_006772391.1 CDS O3M_23925 NC_018650.1 4960293 4960997 R COG1309 Transcriptional regulator; DNA-binding transcriptional repressor FabR complement(4960293..4960997) Escherichia coli O104:H4 str. 2009EL-2050 13692773 YP_006772392.1 CDS O3M_23930 NC_018650.1 4961274 4962674 D COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; soluble pyridine nucleotide transhydrogenase 4961274..4962674 Escherichia coli O104:H4 str. 2009EL-2050 13692774 YP_006772393.1 CDS O3M_23935 NC_018650.1 4962657 4963574 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator OxyR complement(4962657..4963574) Escherichia coli O104:H4 str. 2009EL-2050 13692775 YP_006772394.1 CDS O3M_23940 NC_018650.1 4963825 4965108 R COG0477 Permeases of the major facilitator superfamily; transporter complement(4963825..4965108) Escherichia coli O104:H4 str. 2009EL-2050 13692776 YP_006772395.1 CDS O3M_23945 NC_018650.1 4965175 4966389 R COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; bifunctional D-altronate/D-mannonate dehydratase complement(4965175..4966389) Escherichia coli O104:H4 str. 2009EL-2050 13692777 YP_006772396.1 CDS O3M_23950 NC_018650.1 4966887 4968260 R COG0165 Argininosuccinate lyase; argininosuccinate lyase complement(4966887..4968260) Escherichia coli O104:H4 str. 2009EL-2050 13692778 YP_006772397.1 CDS O3M_23955 NC_018650.1 4968321 4969094 R COG0548 Acetylglutamate kinase; acetylglutamate kinase complement(4968321..4969094) Escherichia coli O104:H4 str. 2009EL-2050 13692779 YP_006772398.1 CDS argC NC_018650.1 4969105 4970109 R COG0002 Acetylglutamate semialdehyde dehydrogenase; N-acetyl-gamma-glutamyl-phosphate reductase complement(4969105..4970109) Escherichia coli O104:H4 str. 2009EL-2050 13692780 YP_006772399.1 CDS O3M_23965 NC_018650.1 4970263 4971414 D COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase 4970263..4971414 Escherichia coli O104:H4 str. 2009EL-2050 13692781 YP_006772400.1 CDS O3M_23970 NC_018650.1 4971766 4974417 D COG2352 Phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase 4971766..4974417 Escherichia coli O104:H4 str. 2009EL-2050 13692782 YP_006772401.1 CDS O3M_23975 NC_018650.1 4974600 4976333 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; hypothetical protein 4974600..4976333 Escherichia coli O104:H4 str. 2009EL-2050 13692783 YP_006772402.1 CDS O3M_23980 NC_018650.1 4976548 4977399 D COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 4976548..4977399 Escherichia coli O104:H4 str. 2009EL-2050 13692784 YP_006772403.1 CDS O3M_23985 NC_018650.1 4977386 4977727 R COG1445 Phosphotransferase system fructose-specific component IIB; PTS system fructose-like transporter subunit IIB complement(4977386..4977727) Escherichia coli O104:H4 str. 2009EL-2050 13692785 YP_006772404.1 CDS O3M_23990 NC_018650.1 4977729 4978607 R COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase II activase complement(4977729..4978607) Escherichia coli O104:H4 str. 2009EL-2050 13692786 YP_006772405.1 CDS pflD NC_018650.1 4978573 4980870 R COG1882 Pyruvate-formate lyase; formate acetyltransferase 2 complement(4978573..4980870) Escherichia coli O104:H4 str. 2009EL-2050 13692787 YP_006772406.1 CDS O3M_24000 NC_018650.1 4980921 4981241 R COG1445 Phosphotransferase system fructose-specific component IIB; PTS system fructose-like transporter subunit IIB complement(4980921..4981241) Escherichia coli O104:H4 str. 2009EL-2050 13692788 YP_006772407.1 CDS O3M_24005 NC_018650.1 4981256 4982335 R COG1299 Phosphotransferase system, fructose-specific IIC component; PTS system fructose-like transporter subunit IIC complement(4981256..4982335) Escherichia coli O104:H4 str. 2009EL-2050 13692789 YP_006772408.1 CDS O3M_24010 NC_018650.1 4982644 4985145 D enzyme I component ; enzyme IIA component; COG1925 Phosphotransferase system, HPr-related proteins; PTS system transporter Hpr subunit 4982644..4985145 Escherichia coli O104:H4 str. 2009EL-2050 13692790 YP_006772409.1 CDS O3M_24015 NC_018650.1 4985157 4985819 D COG0176 Transaldolase; fructose-6-phosphate aldolase 4985157..4985819 Escherichia coli O104:H4 str. 2009EL-2050 13692791 YP_006772410.1 CDS gldA NC_018650.1 4985830 4986933 D COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase 4985830..4986933 Escherichia coli O104:H4 str. 2009EL-2050 13692792 YP_006772411.1 CDS O3M_24025 NC_018650.1 4986965 4987096 D hypothetical protein 4986965..4987096 Escherichia coli O104:H4 str. 2009EL-2050 13692793 YP_006772412.1 CDS O3M_24030 NC_018650.1 4987208 4987825 D COG3738 Uncharacterized protein conserved in bacteria; hypothetical protein 4987208..4987825 Escherichia coli O104:H4 str. 2009EL-2050 13692794 YP_006772413.1 CDS O3M_24035 NC_018650.1 4987852 4988757 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein complement(4987852..4988757) Escherichia coli O104:H4 str. 2009EL-2050 13692795 YP_006772414.1 CDS O3M_24040 NC_018650.1 4988851 4991031 R COG0376 Catalase (peroxidase I); catalase/hydroperoxidase HPI(I) complement(4988851..4991031) Escherichia coli O104:H4 str. 2009EL-2050 13692796 YP_006772415.1 CDS metF NC_018650.1 4991360 4992250 R COG0685 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase complement(4991360..4992250) Escherichia coli O104:H4 str. 2009EL-2050 13692797 YP_006772416.1 CDS O3M_24050 NC_018650.1 4992326 4992460 D hypothetical protein 4992326..4992460 Escherichia coli O104:H4 str. 2009EL-2050 13692798 YP_006772417.1 CDS metL NC_018650.1 4992599 4995031 R COG0527 Aspartokinases; bifunctional aspartate kinase II/homoserine dehydrogenase II complement(4992599..4995031) Escherichia coli O104:H4 str. 2009EL-2050 13692799 YP_006772418.1 CDS O3M_24060 NC_018650.1 4995034 4996194 R COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine gamma-synthase complement(4995034..4996194) Escherichia coli O104:H4 str. 2009EL-2050 13692800 YP_006772419.1 CDS O3M_24065 NC_018650.1 4996471 4996788 D COG3060 Transcriptional regulator of met regulon; transcriptional repressor protein MetJ 4996471..4996788 Escherichia coli O104:H4 str. 2009EL-2050 13692801 YP_006772420.1 CDS O3M_24080 NC_018650.1 4997600 4997872 D COG3677 Transposase and inactivated derivatives; hypothetical protein 4997600..4997872 Escherichia coli O104:H4 str. 2009EL-2050 13692802 YP_006772421.1 CDS O3M_24085 NC_018650.1 4997899 4998084 D COG1662 Transposase and inactivated derivatives, IS1 family; transposase 4997899..4998084 Escherichia coli O104:H4 str. 2009EL-2050 13692803 YP_006772422.1 CDS O3M_24090 NC_018650.1 4998078 4998392 D COG1662 Transposase and inactivated derivatives, IS1 family; iso-IS1 InsB protein, transposase 4998078..4998392 Escherichia coli O104:H4 str. 2009EL-2050 13692804 YP_006772423.1 CDS O3M_24095 NC_018650.1 4998448 4998684 R hypothetical protein complement(4998448..4998684) Escherichia coli O104:H4 str. 2009EL-2050 13692805 YP_006772424.1 CDS O3M_24100 NC_018650.1 4998686 5002870 R COG3209 Rhs family protein; rhsB element core protein RshB complement(4998686..5002870) Escherichia coli O104:H4 str. 2009EL-2050 13692806 YP_006772425.1 CDS rpmE NC_018650.1 5003030 5003242 R COG0254 Ribosomal protein L31; 50S ribosomal protein L31 complement(5003030..5003242) Escherichia coli O104:H4 str. 2009EL-2050 13692807 YP_006772426.1 CDS O3M_24110 NC_018650.1 5003445 5005643 D COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; primosome assembly protein PriA 5003445..5005643 Escherichia coli O104:H4 str. 2009EL-2050 13692808 YP_006772427.1 CDS O3M_24115 NC_018650.1 5005799 5006824 D COG1609 Transcriptional regulators; DNA-binding transcriptional regulator CytR 5005799..5006824 Escherichia coli O104:H4 str. 2009EL-2050 13692809 YP_006772428.1 CDS O3M_24120 NC_018650.1 5006916 5007875 D COG3087 Cell division protein; cell division protein FtsN 5006916..5007875 Escherichia coli O104:H4 str. 2009EL-2050 13692810 YP_006772429.1 CDS O3M_24125 NC_018650.1 5007968 5008498 D COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit; ATP-dependent protease subunit HslV 5007968..5008498 Escherichia coli O104:H4 str. 2009EL-2050 13692811 YP_006772430.1 CDS hslU NC_018650.1 5008508 5009839 D COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit; ATP-dependent protease ATP-binding subunit HslU 5008508..5009839 Escherichia coli O104:H4 str. 2009EL-2050 13692812 YP_006772431.1 CDS O3M_24135 NC_018650.1 5009906 5010832 D COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 5009906..5010832 Escherichia coli O104:H4 str. 2009EL-2050 13692813 YP_006772432.1 CDS O3M_24140 NC_018650.1 5010925 5011410 D COG0684 Demethylmenaquinone methyltransferase; ribonuclease activity regulator protein RraA 5010925..5011410 Escherichia coli O104:H4 str. 2009EL-2050 13692814 YP_006772433.1 CDS O3M_24145 NC_018650.1 5011495 5011734 R COG3074 Uncharacterized protein conserved in bacteria; septal ring assembly protein ZapB complement(5011495..5011734) Escherichia coli O104:H4 str. 2009EL-2050 13692815 YP_006772434.1 CDS O3M_24150 NC_018650.1 5012166 5013011 D COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator protein 5012166..5013011 Escherichia coli O104:H4 str. 2009EL-2050 13692816 YP_006772435.1 CDS glpK NC_018650.1 5013034 5014542 D COG0554 Glycerol kinase; glycerol kinase 5013034..5014542 Escherichia coli O104:H4 str. 2009EL-2050 13692817 YP_006772436.1 CDS glpX NC_018650.1 5014678 5015688 D COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; fructose 1,6-bisphosphatase II 5014678..5015688 Escherichia coli O104:H4 str. 2009EL-2050 13692818 YP_006772437.1 CDS O3M_24165 NC_018650.1 5015785 5016531 D COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; ferredoxin-NADP reductase 5015785..5016531 Escherichia coli O104:H4 str. 2009EL-2050 13692819 YP_006772438.1 CDS O3M_24170 NC_018650.1 5016536 5016964 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspD complement(5016536..5016964) Escherichia coli O104:H4 str. 2009EL-2050 13692820 YP_006772439.1 CDS O3M_24175 NC_018650.1 5016991 5017290 R COG3691 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5016991..5017290) Escherichia coli O104:H4 str. 2009EL-2050 13692821 YP_006772440.1 CDS O3M_24180 NC_018650.1 5017502 5017942 R COG3152 Predicted membrane protein; inner membrane protein complement(5017502..5017942) Escherichia coli O104:H4 str. 2009EL-2050 13692822 YP_006772441.1 CDS O3M_24185 NC_018650.1 5018043 5018642 D hypothetical protein 5018043..5018642 Escherichia coli O104:H4 str. 2009EL-2050 13692823 YP_006772442.1 CDS tpiA NC_018650.1 5018750 5019517 D COG0149 Triosephosphate isomerase; triosephosphate isomerase 5018750..5019517 Escherichia coli O104:H4 str. 2009EL-2050 13692824 YP_006772443.1 CDS O3M_24195 NC_018650.1 5019572 5020327 R COG2134 CDP-diacylglycerol pyrophosphatase; CDP-diacylglycerol pyrophosphatase complement(5019572..5020327) Escherichia coli O104:H4 str. 2009EL-2050 13692825 YP_006772444.1 CDS O3M_24200 NC_018650.1 5020434 5021423 R COG1613 ABC-type sulfate transport system, periplasmic component; sulfate transporter subunit complement(5020434..5021423) Escherichia coli O104:H4 str. 2009EL-2050 13692826 YP_006772445.1 CDS O3M_24205 NC_018650.1 5021743 5022705 R COG0205 6-phosphofructokinase; 6-phosphofructokinase complement(5021743..5022705) Escherichia coli O104:H4 str. 2009EL-2050 13692827 YP_006772446.1 CDS fieF NC_018650.1 5022886 5023788 R COG0053 Predicted Co/Zn/Cd cation transporters; ferrous iron efflux protein F complement(5022886..5023788) Escherichia coli O104:H4 str. 2009EL-2050 13692828 YP_006772447.1 CDS cpxP NC_018650.1 5023937 5024437 R COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; repressor CpxP complement(5023937..5024437) Escherichia coli O104:H4 str. 2009EL-2050 13692829 YP_006772448.1 CDS O3M_24220 NC_018650.1 5024587 5025285 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator CpxR 5024587..5025285 Escherichia coli O104:H4 str. 2009EL-2050 13692830 YP_006772449.1 CDS cpxA NC_018650.1 5025282 5026655 D COG0642 Signal transduction histidine kinase; two-component sensor protein 5025282..5026655 Escherichia coli O104:H4 str. 2009EL-2050 13692831 YP_006772450.1 CDS O3M_24230 NC_018650.1 5026761 5027435 R COG2258 Uncharacterized protein conserved in bacteria; 6-N-hydroxylaminopurine resistance protein complement(5026761..5027435) Escherichia coli O104:H4 str. 2009EL-2050 13692832 YP_006772451.1 CDS O3M_24235 NC_018650.1 5027584 5028567 R 2-keto-3-deoxygluconate permease complement(5027584..5028567) Escherichia coli O104:H4 str. 2009EL-2050 13692833 YP_006772452.1 CDS O3M_24240 NC_018650.1 5028827 5029447 R COG0605 Superoxide dismutase; superoxide dismutase complement(5028827..5029447) Escherichia coli O104:H4 str. 2009EL-2050 13692834 YP_006772453.1 CDS O3M_24245 NC_018650.1 5029732 5030766 D rhamnose-proton symporter 5029732..5030766 Escherichia coli O104:H4 str. 2009EL-2050 13692835 YP_006772454.1 CDS O3M_24250 NC_018650.1 5030763 5031701 R COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator RhaR complement(5030763..5031701) Escherichia coli O104:H4 str. 2009EL-2050 13692836 YP_006772455.1 CDS O3M_24255 NC_018650.1 5031685 5032521 R COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator RhaS complement(5031685..5032521) Escherichia coli O104:H4 str. 2009EL-2050 13692837 YP_006772456.1 CDS O3M_24260 NC_018650.1 5032581 5032730 R hypothetical protein complement(5032581..5032730) Escherichia coli O104:H4 str. 2009EL-2050 13692838 YP_006772457.1 CDS rhaB NC_018650.1 5032809 5034278 D COG1070 Sugar (pentulose and hexulose) kinases; rhamnulokinase 5032809..5034278 Escherichia coli O104:H4 str. 2009EL-2050 13692839 YP_006772458.1 CDS O3M_24270 NC_018650.1 5034275 5035534 D COG4806 L-rhamnose isomerase; L-rhamnose isomerase 5034275..5035534 Escherichia coli O104:H4 str. 2009EL-2050 13692840 YP_006772459.1 CDS O3M_24275 NC_018650.1 5035776 5036600 D COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; rhamnulose-1-phosphate aldolase 5035776..5036600 Escherichia coli O104:H4 str. 2009EL-2050 13692841 YP_006772460.1 CDS O3M_24280 NC_018650.1 5036610 5036924 D COG3254 Uncharacterized conserved protein; L-rhamnose mutarotase 5036610..5036924 Escherichia coli O104:H4 str. 2009EL-2050 13692842 YP_006772461.1 CDS O3M_24285 NC_018650.1 5037237 5037683 D COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); fructose-like phosphotransferase system subunit EIIA 5037237..5037683 Escherichia coli O104:H4 str. 2009EL-2050 13692843 YP_006772462.1 CDS O3M_24290 NC_018650.1 5037694 5039145 D COG1445 Phosphotransferase system fructose-specific component IIB; PTS system transporter subunits IIBC 5037694..5039145 Escherichia coli O104:H4 str. 2009EL-2050 13692844 YP_006772463.1 CDS O3M_24295 NC_018650.1 5039135 5040205 D COG1363 Cellulase M and related proteins; peptidase 5039135..5040205 Escherichia coli O104:H4 str. 2009EL-2050 13692845 YP_006772464.1 CDS O3M_24300 NC_018650.1 5040205 5041953 D COG3711 Transcriptional antiterminator; frv operon regulatory protein 5040205..5041953 Escherichia coli O104:H4 str. 2009EL-2050 13692846 YP_006772465.1 CDS O3M_24305 NC_018650.1 5042003 5043043 R hypothetical protein complement(5042003..5043043) Escherichia coli O104:H4 str. 2009EL-2050 13692847 YP_006772466.1 CDS O3M_24310 NC_018650.1 5043196 5044029 R COG1526 Uncharacterized protein required for formate dehydrogenase activity; formate dehydrogenase accessory protein complement(5043196..5044029) Escherichia coli O104:H4 str. 2009EL-2050 13692848 YP_006772467.1 CDS O3M_24315 NC_018650.1 5044223 5044810 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-O, large subunit 5044223..5044810 Escherichia coli O104:H4 str. 2009EL-2050 13692849 YP_006772468.1 CDS O3M_24320 NC_018650.1 5044859 5047273 D COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-O, major subunit 5044859..5047273 Escherichia coli O104:H4 str. 2009EL-2050 13692850 YP_006772469.1 CDS O3M_24325 NC_018650.1 5047286 5048188 D COG0437 Fe-S-cluster-containing hydrogenase components 1; formate dehydrogenase-O, iron-sulfur subunit 5047286..5048188 Escherichia coli O104:H4 str. 2009EL-2050 13692851 YP_006772470.1 CDS O3M_24330 NC_018650.1 5048185 5048820 D COG2864 Cytochrome b subunit of formate dehydrogenase; formate dehydrogenase-O subunit gamma 5048185..5048820 Escherichia coli O104:H4 str. 2009EL-2050 13692852 YP_006772471.1 CDS O3M_24335 NC_018650.1 5048817 5049746 D COG3058 Uncharacterized protein involved in formate dehydrogenase formation; formate dehydrogenase accessory protein FdhE 5048817..5049746 Escherichia coli O104:H4 str. 2009EL-2050 13692853 YP_006772472.1 CDS O3M_24340 NC_018650.1 5049926 5050060 D hypothetical protein 5049926..5050060 Escherichia coli O104:H4 str. 2009EL-2050 13692854 YP_006772473.1 CDS O3M_24345 NC_018650.1 5050076 5050318 R COG1219 ATP-dependent protease Clp, ATPase subunit; hypothetical protein complement(5050076..5050318) Escherichia coli O104:H4 str. 2009EL-2050 13692855 YP_006772474.1 CDS O3M_24350 NC_018650.1 5050538 5050756 R COG3905 Predicted transcriptional regulator; transcriptional regulator complement(5050538..5050756) Escherichia coli O104:H4 str. 2009EL-2050 13692856 YP_006772475.1 CDS O3M_24355 NC_018650.1 5051342 5051632 R COG2944 Predicted transcriptional regulator; hypothetical protein complement(5051342..5051632) Escherichia coli O104:H4 str. 2009EL-2050 13692857 YP_006772476.1 CDS O3M_24360 NC_018650.1 5051633 5051944 R hypothetical protein complement(5051633..5051944) Escherichia coli O104:H4 str. 2009EL-2050 13692858 YP_006772477.1 CDS O3M_24365 NC_018650.1 5052173 5053081 D COG0657 Esterase/lipase; lipase 5052173..5053081 Escherichia coli O104:H4 str. 2009EL-2050 13692859 YP_006772478.1 CDS O3M_24370 NC_018650.1 5053145 5054134 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase complement(5053145..5054134) Escherichia coli O104:H4 str. 2009EL-2050 13692860 YP_006772479.1 CDS O3M_24375 NC_018650.1 5054131 5054568 R COG1490 D-Tyr-tRNAtyr deacylase; D-tyrosyl-tRNA(Tyr) deacylase complement(5054131..5054568) Escherichia coli O104:H4 str. 2009EL-2050 13692861 YP_006772480.1 CDS O3M_24380 NC_018650.1 5054565 5055437 R COG1295 Predicted membrane protein; hypothetical protein complement(5054565..5055437) Escherichia coli O104:H4 str. 2009EL-2050 13692862 YP_006772481.1 CDS O3M_24385 NC_018650.1 5055431 5056030 R COG1011 Predicted hydrolase (HAD superfamily); alpha-D-glucose-1-phosphatase complement(5055431..5056030) Escherichia coli O104:H4 str. 2009EL-2050 13692863 YP_006772482.1 CDS O3M_24390 NC_018650.1 5056171 5057058 R COG2017 Galactose mutarotase and related enzymes; galactose mutarotase complement(5056171..5057058) Escherichia coli O104:H4 str. 2009EL-2050 13692864 YP_006772483.1 CDS O3M_24395 NC_018650.1 5057048 5058397 R COG0477 Permeases of the major facilitator superfamily; transporter complement(5057048..5058397) Escherichia coli O104:H4 str. 2009EL-2050 13692865 YP_006772484.1 CDS O3M_24400 NC_018650.1 5058496 5059929 R COG0477 Permeases of the major facilitator superfamily; transporter complement(5058496..5059929) Escherichia coli O104:H4 str. 2009EL-2050 13692866 YP_006772485.1 CDS O3M_24405 NC_018650.1 5059999 5061009 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; dehydrogenase, GroES-like protein complement(5059999..5061009) Escherichia coli O104:H4 str. 2009EL-2050 13692867 YP_006772486.1 CDS O3M_24410 NC_018650.1 5061042 5061929 R COG3684 Tagatose-1,6-bisphosphate aldolase; aldolase yihT complement(5061042..5061929) Escherichia coli O104:H4 str. 2009EL-2050 13692868 YP_006772487.1 CDS O3M_24415 NC_018650.1 5061954 5062832 R COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; NADH-dependent gamma-hydroxybutyrate dehydrogenase complement(5061954..5062832) Escherichia coli O104:H4 str. 2009EL-2050 13692869 YP_006772488.1 CDS O3M_24420 NC_018650.1 5063005 5063901 D COG0524 Sugar kinases, ribokinase family; sugar kinase 5063005..5063901 Escherichia coli O104:H4 str. 2009EL-2050 13692870 YP_006772489.1 CDS O3M_24425 NC_018650.1 5063941 5064729 D COG1349 Transcriptional regulators of sugar metabolism; DEOR-type transcriptional regulator 5063941..5064729 Escherichia coli O104:H4 str. 2009EL-2050 13692871 YP_006772490.1 CDS O3M_24430 NC_018650.1 5064840 5066105 R COG0477 Permeases of the major facilitator superfamily; transporter complement(5064840..5066105) Escherichia coli O104:H4 str. 2009EL-2050 13692872 YP_006772491.1 CDS O3M_24435 NC_018650.1 5066207 5067187 R COG1082 Sugar phosphate isomerases/epimerases; sugar phosphate isomerase complement(5066207..5067187) Escherichia coli O104:H4 str. 2009EL-2050 13692873 YP_006772492.1 CDS O3M_24440 NC_018650.1 5067195 5067905 R COG2188 Transcriptional regulators; DNA-binding transcriptional regulator complement(5067195..5067905) Escherichia coli O104:H4 str. 2009EL-2050 13692874 YP_006772493.1 CDS O3M_24445 NC_018650.1 5068122 5069945 R COG1217 Predicted membrane GTPase involved in stress response; GTP-binding protein complement(5068122..5069945) Escherichia coli O104:H4 str. 2009EL-2050 13692875 YP_006772494.1 CDS glnA NC_018650.1 5070318 5071727 D COG0174 Glutamine synthetase; glutamine synthetase 5070318..5071727 Escherichia coli O104:H4 str. 2009EL-2050 13692876 YP_006772495.1 CDS glnL NC_018650.1 5072013 5073062 D COG3852 Signal transduction histidine kinase, nitrogen specific; nitrogen regulation protein NR(II) 5072013..5073062 Escherichia coli O104:H4 str. 2009EL-2050 13692877 YP_006772496.1 CDS glnG NC_018650.1 5073074 5074483 D COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; nitrogen regulation protein NR(I) 5073074..5074483 Escherichia coli O104:H4 str. 2009EL-2050 13692878 YP_006772497.1 CDS O3M_24465 NC_018650.1 5074595 5074705 D hypothetical protein 5074595..5074705 Escherichia coli O104:H4 str. 2009EL-2050 13692879 YP_006772498.1 CDS O3M_24470 NC_018650.1 5074895 5076268 R COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; coproporphyrinogen III oxidase complement(5074895..5076268) Escherichia coli O104:H4 str. 2009EL-2050 13692880 YP_006772499.1 CDS O3M_24475 NC_018650.1 5076457 5076966 R COG3078 Uncharacterized protein conserved in bacteria; GTPase activator complement(5076457..5076966) Escherichia coli O104:H4 str. 2009EL-2050 13692881 YP_006772500.1 CDS O3M_24480 NC_018650.1 5077174 5077251 R hypothetical protein complement(5077174..5077251) Escherichia coli O104:H4 str. 2009EL-2050 13692882 YP_006772501.1 CDS engB NC_018650.1 5077548 5078180 D COG0218 Predicted GTPase; GTP-binding protein YsxC 5077548..5078180 Escherichia coli O104:H4 str. 2009EL-2050 13692883 YP_006772502.1 CDS O3M_24490 NC_018650.1 5078562 5081348 R COG0258 5'-3' exonuclease (including N-terminal domain of PolI); DNA polymerase I complement(5078562..5081348) Escherichia coli O104:H4 str. 2009EL-2050 13692884 YP_006772503.1 CDS O3M_24495 NC_018650.1 5081350 5081592 D hypothetical protein 5081350..5081592 Escherichia coli O104:H4 str. 2009EL-2050 13692885 YP_006772504.1 CDS O3M_24500 NC_018650.1 5081712 5082644 D COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; acyltransferase 5081712..5082644 Escherichia coli O104:H4 str. 2009EL-2050 13692886 YP_006772505.1 CDS O3M_24505 NC_018650.1 5082685 5084115 R COG5339 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5082685..5084115) Escherichia coli O104:H4 str. 2009EL-2050 13692887 YP_006772506.1 CDS O3M_24510 NC_018650.1 5084270 5084896 R COG0526 Thiol-disulfide isomerase and thioredoxins; protein disulfide isomerase I complement(5084270..5084896) Escherichia coli O104:H4 str. 2009EL-2050 13692888 YP_006772507.1 CDS O3M_24515 NC_018650.1 5084913 5085899 R COG2334 Putative homoserine kinase type II (protein kinase fold); serine/threonine protein kinase complement(5084913..5085899) Escherichia coli O104:H4 str. 2009EL-2050 13692889 YP_006772508.1 CDS O3M_24520 NC_018650.1 5085976 5086245 R COG3084 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5085976..5086245) Escherichia coli O104:H4 str. 2009EL-2050 13692890 YP_006772509.1 CDS mobA NC_018650.1 5086315 5086899 D COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; molybdopterin-guanine dinucleotide biosynthesis protein MobA 5086315..5086899 Escherichia coli O104:H4 str. 2009EL-2050 13692891 YP_006772510.1 CDS O3M_24530 NC_018650.1 5086881 5087408 D COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; molybdopterin-guanine dinucleotide biosynthesis protein MobB 5086881..5087408 Escherichia coli O104:H4 str. 2009EL-2050 13692892 YP_006772511.1 CDS hemG NC_018650.1 5092993 5093538 R COG4635 Flavodoxin; protoporphyrinogen oxidase complement(5092993..5093538) Escherichia coli O104:H4 str. 2009EL-2050 13692898 YP_006772512.1 CDS O3M_24540 NC_018650.1 5093550 5095001 R COG0168 Trk-type K+ transport systems, membrane components; potassium transporter complement(5093550..5095001) Escherichia coli O104:H4 str. 2009EL-2050 13692899 YP_006772513.1 CDS O3M_24545 NC_018650.1 5095040 5095654 R COG1739 Uncharacterized conserved protein; hypothetical protein complement(5095040..5095654) Escherichia coli O104:H4 str. 2009EL-2050 13692900 YP_006772514.1 CDS O3M_24550 NC_018650.1 5095654 5096985 R COG0006 Xaa-Pro aminopeptidase; proline dipeptidase complement(5095654..5096985) Escherichia coli O104:H4 str. 2009EL-2050 13692901 YP_006772515.1 CDS fadB NC_018650.1 5097175 5099364 D COG1024 Enoyl-CoA hydratase/carnithine racemase; multifunctional fatty acid oxidation complex subunit alpha 5097175..5099364 Escherichia coli O104:H4 str. 2009EL-2050 13692902 YP_006772516.1 CDS fadA NC_018650.1 5099374 5100537 D COG0183 Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase 5099374..5100537 Escherichia coli O104:H4 str. 2009EL-2050 13692903 YP_006772517.1 CDS fre NC_018650.1 5100729 5101430 R COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; FMN reductase complement(5100729..5101430) Escherichia coli O104:H4 str. 2009EL-2050 13692904 YP_006772518.1 CDS O3M_24570 NC_018650.1 5101476 5102969 R COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(5101476..5102969) Escherichia coli O104:H4 str. 2009EL-2050 13692905 YP_006772519.1 CDS rfaH NC_018650.1 5103136 5103624 D COG0250 Transcription antiterminator; transcriptional activator RfaH 5103136..5103624 Escherichia coli O104:H4 str. 2009EL-2050 13692906 YP_006772520.1 CDS O3M_24580 NC_018650.1 5103621 5104403 R COG0084 Mg-dependent DNase; DNase TatD complement(5103621..5104403) Escherichia coli O104:H4 str. 2009EL-2050 13692907 YP_006772521.1 CDS O3M_24585 NC_018650.1 5104445 5105221 R COG0805 Sec-independent protein secretion pathway component TatC; twin-arginine protein translocation system subunit TatC complement(5104445..5105221) Escherichia coli O104:H4 str. 2009EL-2050 13692908 YP_006772522.1 CDS O3M_24590 NC_018650.1 5105224 5105739 R COG1826 Sec-independent protein secretion pathway components; sec-independent translocase complement(5105224..5105739) Escherichia coli O104:H4 str. 2009EL-2050 13692909 YP_006772523.1 CDS tatA NC_018650.1 5105743 5106012 R COG1826 Sec-independent protein secretion pathway components; twin arginine translocase protein A complement(5105743..5106012) Escherichia coli O104:H4 str. 2009EL-2050 13692910 YP_006772524.1 CDS ubiB NC_018650.1 5106091 5107731 R COG0661 Predicted unusual protein kinase; ubiquinone biosynthesis protein UbiB complement(5106091..5107731) Escherichia coli O104:H4 str. 2009EL-2050 13692911 YP_006772525.1 CDS O3M_24605 NC_018650.1 5107728 5108333 R COG3165 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5107728..5108333) Escherichia coli O104:H4 str. 2009EL-2050 13692912 YP_006772526.1 CDS ubiE NC_018650.1 5108347 5109102 R COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; ubiquinone/menaquinone biosynthesis methyltransferase complement(5108347..5109102) Escherichia coli O104:H4 str. 2009EL-2050 13692913 YP_006772527.1 CDS O3M_24615 NC_018650.1 5109197 5110624 R COG1322 Uncharacterized protein conserved in bacteria; DNA recombination protein RmuC complement(5109197..5110624) Escherichia coli O104:H4 str. 2009EL-2050 13692914 YP_006772528.1 CDS O3M_24620 NC_018650.1 5110765 5111526 R COG2820 Uridine phosphorylase; uridine phosphorylase complement(5110765..5111526) Escherichia coli O104:H4 str. 2009EL-2050 13692915 YP_006772529.1 CDS O3M_24625 NC_018650.1 5111788 5112603 D COG0412 Dienelactone hydrolase and related enzymes; hydrolase 5111788..5112603 Escherichia coli O104:H4 str. 2009EL-2050 13692916 YP_006772530.1 CDS O3M_24630 NC_018650.1 5112642 5114903 R COG0620 Methionine synthase II (cobalamin-independent); 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase complement(5112642..5114903) Escherichia coli O104:H4 str. 2009EL-2050 13692917 YP_006772531.1 CDS O3M_24635 NC_018650.1 5115021 5115974 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator MetR 5115021..5115974 Escherichia coli O104:H4 str. 2009EL-2050 13692918 YP_006772532.1 CDS O3M_24640 NC_018650.1 5115862 5116761 R COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein complement(5115862..5116761) Escherichia coli O104:H4 str. 2009EL-2050 13692919 YP_006772533.1 CDS O3M_24645 NC_018650.1 5116837 5117637 R COG0561 Predicted hydrolases of the HAD superfamily; hydrolase complement(5116837..5117637) Escherichia coli O104:H4 str. 2009EL-2050 13692920 YP_006772534.1 CDS O3M_24650 NC_018650.1 5117645 5118667 R COG2267 Lysophospholipase; lysophospholipase L2 complement(5117645..5118667) Escherichia coli O104:H4 str. 2009EL-2050 13692921 YP_006772535.1 CDS rhtB NC_018650.1 5118778 5119398 D COG1280 Putative threonine efflux protein; homoserine/homoserine lactone efflux protein 5118778..5119398 Escherichia coli O104:H4 str. 2009EL-2050 13692922 YP_006772536.1 CDS O3M_24660 NC_018650.1 5119460 5120080 R COG1280 Putative threonine efflux protein; threonine efflux system complement(5119460..5120080) Escherichia coli O104:H4 str. 2009EL-2050 13692923 YP_006772537.1 CDS O3M_24665 NC_018650.1 5120144 5121973 R COG0514 Superfamily II DNA helicase; ATP-dependent DNA helicase RecQ complement(5120144..5121973) Escherichia coli O104:H4 str. 2009EL-2050 13692924 YP_006772538.1 CDS O3M_24670 NC_018650.1 5122106 5122975 R COG2829 Outer membrane phospholipase A; phospholipase A complement(5122106..5122975) Escherichia coli O104:H4 str. 2009EL-2050 13692925 YP_006772539.1 CDS O3M_24675 NC_018650.1 5123140 5123607 D COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein 5123140..5123607 Escherichia coli O104:H4 str. 2009EL-2050 13692926 YP_006772540.1 CDS O3M_24680 NC_018650.1 5123659 5124546 D COG2962 Predicted permeases; chloramphenical resistance permease RarD 5123659..5124546 Escherichia coli O104:H4 str. 2009EL-2050 13692927 YP_006772541.1 CDS O3M_24685 NC_018650.1 5124593 5124892 R hypothetical protein complement(5124593..5124892) Escherichia coli O104:H4 str. 2009EL-2050 13692928 YP_006772542.1 CDS O3M_24690 NC_018650.1 5125538 5125657 R COG0598 Mg2+ and Co2+ transporters; magnesium/nickel/cobalt transporter CorA complement(5125538..5125657) Escherichia coli O104:H4 str. 2009EL-2050 13692929 YP_006772543.1 CDS O3M_24695 NC_018650.1 5125871 5126719 D hypothetical protein 5125871..5126719 Escherichia coli O104:H4 str. 2009EL-2050 13692930 YP_006772544.1 CDS O3M_24700 NC_018650.1 5126716 5127207 D hypothetical protein 5126716..5127207 Escherichia coli O104:H4 str. 2009EL-2050 13692931 YP_006772545.1 CDS O3M_24705 NC_018650.1 5127249 5128199 R COG0598 Mg2+ and Co2+ transporters; magnesium/nickel/cobalt transporter CorA complement(5127249..5128199) Escherichia coli O104:H4 str. 2009EL-2050 13692932 YP_006772546.1 CDS O3M_24710 NC_018650.1 5128443 5128577 R hypothetical protein complement(5128443..5128577) Escherichia coli O104:H4 str. 2009EL-2050 13692933 YP_006772547.1 CDS O3M_24715 NC_018650.1 5128569 5129333 D COG3698 Predicted periplasmic protein; hypothetical protein 5128569..5129333 Escherichia coli O104:H4 str. 2009EL-2050 13692934 YP_006772548.1 CDS uvrD NC_018650.1 5129480 5131642 R COG0210 Superfamily I DNA and RNA helicases; DNA-dependent helicase II complement(5129480..5131642) Escherichia coli O104:H4 str. 2009EL-2050 13692935 YP_006772549.1 CDS O3M_24725 NC_018650.1 5131726 5132442 R COG1011 Predicted hydrolase (HAD superfamily); flavin mononucleotide phosphatase complement(5131726..5132442) Escherichia coli O104:H4 str. 2009EL-2050 13692936 YP_006772550.1 CDS xerC NC_018650.1 5132442 5133338 R COG4973 Site-specific recombinase XerC; site-specific tyrosine recombinase XerC complement(5132442..5133338) Escherichia coli O104:H4 str. 2009EL-2050 13692937 YP_006772551.1 CDS O3M_24735 NC_018650.1 5133335 5134042 R COG3159 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5133335..5134042) Escherichia coli O104:H4 str. 2009EL-2050 13692938 YP_006772552.1 CDS dapF NC_018650.1 5134039 5134863 R COG0253 Diaminopimelate epimerase; diaminopimelate epimerase complement(5134039..5134863) Escherichia coli O104:H4 str. 2009EL-2050 13692939 YP_006772553.1 CDS O3M_24745 NC_018650.1 5134900 5135103 R COG5567 Predicted small periplasmic lipoprotein; lipoprotein complement(5134900..5135103) Escherichia coli O104:H4 str. 2009EL-2050 13692940 YP_006772554.1 CDS O3M_24750 NC_018650.1 5135453 5136007 D hypothetical protein 5135453..5136007 Escherichia coli O104:H4 str. 2009EL-2050 13692941 YP_006772555.1 CDS O3M_24755 NC_018650.1 5136375 5137853 D hypothetical protein 5136375..5137853 Escherichia coli O104:H4 str. 2009EL-2050 13692942 YP_006772556.1 CDS O3M_24760 NC_018650.1 5137850 5139175 D hypothetical protein 5137850..5139175 Escherichia coli O104:H4 str. 2009EL-2050 13692943 YP_006772557.1 CDS cyaY NC_018650.1 5139223 5139543 D COG1965 Protein implicated in iron transport, frataxin homolog; frataxin-like protein 5139223..5139543 Escherichia coli O104:H4 str. 2009EL-2050 13692944 YP_006772558.1 CDS cyaA NC_018650.1 5139583 5142129 R COG3072 Adenylate cyclase; adenylate cyclase complement(5139583..5142129) Escherichia coli O104:H4 str. 2009EL-2050 13692945 YP_006772559.1 CDS hemC NC_018650.1 5142516 5143457 D COG0181 Porphobilinogen deaminase; porphobilinogen deaminase 5142516..5143457 Escherichia coli O104:H4 str. 2009EL-2050 13692946 YP_006772560.1 CDS hemD NC_018650.1 5143454 5144194 D COG1587 Uroporphyrinogen-III synthase; uroporphyrinogen-III synthase 5143454..5144194 Escherichia coli O104:H4 str. 2009EL-2050 13692947 YP_006772561.1 CDS O3M_24785 NC_018650.1 5144216 5145451 D COG2959 Uncharacterized enzyme of heme biosynthesis; uroporphyrinogen III C-methyltransferase 5144216..5145451 Escherichia coli O104:H4 str. 2009EL-2050 13692948 YP_006772562.1 CDS O3M_24790 NC_018650.1 5145454 5146650 D COG3071 Uncharacterized enzyme of heme biosynthesis; protoheme IX biogenesis protein 5145454..5146650 Escherichia coli O104:H4 str. 2009EL-2050 13692949 YP_006772563.1 CDS O3M_24795 NC_018650.1 5147329 5147490 D hypothetical protein 5147329..5147490 Escherichia coli O104:H4 str. 2009EL-2050 13692950 YP_006772564.1 CDS O3M_24800 NC_018650.1 5147574 5148809 R COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); regulator of arylsulfatase activity complement(5147574..5148809) Escherichia coli O104:H4 str. 2009EL-2050 13692951 YP_006772565.1 CDS O3M_24805 NC_018650.1 5149495 5150880 R COG1113 Gamma-aminobutyrate permease and related permeases; transporter complement(5149495..5150880) Escherichia coli O104:H4 str. 2009EL-2050 13692956 YP_006772566.1 CDS O3M_24810 NC_018650.1 5151071 5151811 R COG1922 Teichoic acid biosynthesis proteins; UDP-N-acetyl-D-mannosaminuronic acid transferase complement(5151071..5151811) Escherichia coli O104:H4 str. 2009EL-2050 13692957 YP_006772567.1 CDS O3M_24815 NC_018650.1 5151814 5153166 R common antigen polymerase complement(5151814..5153166) Escherichia coli O104:H4 str. 2009EL-2050 13692958 YP_006772568.1 CDS O3M_24820 NC_018650.1 5153163 5154242 R 4-alpha-L-fucosyltransferase complement(5153163..5154242) Escherichia coli O104:H4 str. 2009EL-2050 13692959 YP_006772569.1 CDS O3M_24825 NC_018650.1 5154239 5155489 R COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; O-antigen translocase complement(5154239..5155489) Escherichia coli O104:H4 str. 2009EL-2050 13692960 YP_006772570.1 CDS O3M_24830 NC_018650.1 5155491 5156621 R COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; TDP-4-oxo-6-deoxy-D-glucose transaminase complement(5155491..5156621) Escherichia coli O104:H4 str. 2009EL-2050 13692961 YP_006772571.1 CDS O3M_24835 NC_018650.1 5156626 5157300 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; TDP-fucosamine acetyltransferase complement(5156626..5157300) Escherichia coli O104:H4 str. 2009EL-2050 13692962 YP_006772572.1 CDS O3M_24840 NC_018650.1 5157278 5158159 R COG1209 dTDP-glucose pyrophosphorylase; glucose-1-phosphate thymidylyltransferase complement(5157278..5158159) Escherichia coli O104:H4 str. 2009EL-2050 13692963 YP_006772573.1 CDS O3M_24845 NC_018650.1 5158178 5159245 R COG1088 dTDP-D-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase complement(5158178..5159245) Escherichia coli O104:H4 str. 2009EL-2050 13692964 YP_006772574.1 CDS wecC NC_018650.1 5159245 5160507 R COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; UDP-N-acetyl-D-mannosamine dehydrogenase complement(5159245..5160507) Escherichia coli O104:H4 str. 2009EL-2050 13692965 YP_006772575.1 CDS O3M_24855 NC_018650.1 5160504 5161634 R COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase complement(5160504..5161634) Escherichia coli O104:H4 str. 2009EL-2050 13692966 YP_006772576.1 CDS O3M_24860 NC_018650.1 5161690 5162736 R COG3765 Chain length determinant protein; lipopolysaccharide biosynthesis protein WzzE complement(5161690..5162736) Escherichia coli O104:H4 str. 2009EL-2050 13692967 YP_006772577.1 CDS O3M_24865 NC_018650.1 5162748 5163851 R COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase complement(5162748..5163851) Escherichia coli O104:H4 str. 2009EL-2050 13692968 YP_006772578.1 CDS O3M_24870 NC_018650.1 5163863 5164081 R hypothetical protein complement(5163863..5164081) Escherichia coli O104:H4 str. 2009EL-2050 13692969 YP_006772579.1 CDS rho NC_018650.1 5164091 5165350 R COG1158 Transcription termination factor; transcription termination factor Rho complement(5164091..5165350) Escherichia coli O104:H4 str. 2009EL-2050 13692970 YP_006772580.1 CDS O3M_24880 NC_018650.1 5165435 5165536 R rho operon leader peptide complement(5165435..5165536) Escherichia coli O104:H4 str. 2009EL-2050 13692971 YP_006772581.1 CDS trxA NC_018650.1 5165677 5166006 R COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin complement(5165677..5166006) Escherichia coli O104:H4 str. 2009EL-2050 13692972 YP_006772582.1 CDS O3M_24890 NC_018650.1 5166137 5167402 D COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlB 5166137..5167402 Escherichia coli O104:H4 str. 2009EL-2050 13692973 YP_006772583.1 CDS O3M_24895 NC_018650.1 5167536 5169020 D COG0248 Exopolyphosphatase; guanosine pentaphosphate phosphohydrolase 5167536..5169020 Escherichia coli O104:H4 str. 2009EL-2050 13692974 YP_006772584.1 CDS O3M_24900 NC_018650.1 5169067 5171088 R COG0210 Superfamily I DNA and RNA helicases; ATP-dependent DNA helicase Rep complement(5169067..5171088) Escherichia coli O104:H4 str. 2009EL-2050 13692975 YP_006772585.1 CDS O3M_24905 NC_018650.1 5171305 5171754 D COG3692 Uncharacterized protein conserved in bacteria; hypothetical protein 5171305..5171754 Escherichia coli O104:H4 str. 2009EL-2050 13692976 YP_006772586.1 CDS O3M_24910 NC_018650.1 5171953 5172234 D COG0760 Parvulin-like peptidyl-prolyl isomerase; peptidyl-prolyl cis-trans isomerase C 5171953..5172234 Escherichia coli O104:H4 str. 2009EL-2050 13692977 YP_006772587.1 CDS O3M_24915 NC_018650.1 5172321 5173796 R COG0059 Ketol-acid reductoisomerase; ketol-acid reductoisomerase complement(5172321..5173796) Escherichia coli O104:H4 str. 2009EL-2050 13692978 YP_006772588.1 CDS O3M_24920 NC_018650.1 5173946 5174839 D COG0583 Transcriptional regulator; DNA-binding transcriptional regulator IlvY 5173946..5174839 Escherichia coli O104:H4 str. 2009EL-2050 13692979 YP_006772589.1 CDS O3M_24925 NC_018650.1 5174891 5176435 R COG1171 Threonine dehydratase; threonine dehydratase complement(5174891..5176435) Escherichia coli O104:H4 str. 2009EL-2050 13692980 YP_006772590.1 CDS O3M_24930 NC_018650.1 5176438 5178288 R COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxy-acid dehydratase complement(5176438..5178288) Escherichia coli O104:H4 str. 2009EL-2050 13692981 YP_006772591.1 CDS O3M_24935 NC_018650.1 5178353 5179282 R COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; branched-chain amino acid aminotransferase complement(5178353..5179282) Escherichia coli O104:H4 str. 2009EL-2050 13692982 YP_006772592.1 CDS ilvM NC_018650.1 5179302 5179565 R COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit; acetolactate synthase 2 regulatory subunit complement(5179302..5179565) Escherichia coli O104:H4 str. 2009EL-2050 13692983 YP_006772593.1 CDS O3M_24945 NC_018650.1 5179562 5181208 R COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase 2 catalytic subunit complement(5179562..5181208) Escherichia coli O104:H4 str. 2009EL-2050 13692984 YP_006772594.1 CDS O3M_24950 NC_018650.1 5181799 5183319 D COG0606 Predicted ATPase with chaperone activity; ATP-dependent protease 5181799..5183319 Escherichia coli O104:H4 str. 2009EL-2050 13692985 YP_006772595.1 CDS O3M_24955 NC_018650.1 5183344 5183682 R COG3085 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5183344..5183682) Escherichia coli O104:H4 str. 2009EL-2050 13692986 YP_006772596.1 CDS O3M_24960 NC_018650.1 5183801 5184640 D COG0583 Transcriptional regulator; transcriptional regulator HdfR 5183801..5184640 Escherichia coli O104:H4 str. 2009EL-2050 13692987 YP_006772597.1 CDS O3M_24965 NC_018650.1 5190441 5191133 D COG2186 Transcriptional regulators; transcriptional regulator 5190441..5191133 Escherichia coli O104:H4 str. 2009EL-2050 13692994 YP_006772598.1 CDS O3M_24970 NC_018650.1 5191156 5192583 D COG0477 Permeases of the major facilitator superfamily; multidrug or homocysteine efflux system 5191156..5192583 Escherichia coli O104:H4 str. 2009EL-2050 13692996 YP_006772599.1 CDS O3M_24975 NC_018650.1 5192549 5193541 R COG1609 Transcriptional regulators; transcriptional repressor RbsR complement(5192549..5193541) Escherichia coli O104:H4 str. 2009EL-2050 13692997 YP_006772600.1 CDS O3M_24980 NC_018650.1 5193545 5194474 R COG0524 Sugar kinases, ribokinase family; ribokinase complement(5193545..5194474) Escherichia coli O104:H4 str. 2009EL-2050 13692998 YP_006772601.1 CDS O3M_24985 NC_018650.1 5194600 5195490 R COG1879 ABC-type sugar transport system, periplasmic component; D-ribose transporter subunit RbsB complement(5194600..5195490) Escherichia coli O104:H4 str. 2009EL-2050 13692999 YP_006772602.1 CDS rbsC NC_018650.1 5195515 5196480 R COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ribose ABC transporter permease complement(5195515..5196480) Escherichia coli O104:H4 str. 2009EL-2050 13693000 YP_006772603.1 CDS O3M_24995 NC_018650.1 5196485 5197990 R COG1129 ABC-type sugar transport system, ATPase component; D-ribose transporter ATP-binding protein complement(5196485..5197990) Escherichia coli O104:H4 str. 2009EL-2050 13693001 YP_006772604.1 CDS O3M_25000 NC_018650.1 5197998 5198417 R COG1869 ABC-type ribose transport system, auxiliary component; D-ribose pyranase complement(5197998..5198417) Escherichia coli O104:H4 str. 2009EL-2050 13693002 YP_006772605.1 CDS trkD NC_018650.1 5198584 5200452 R COG3158 K+ transporter; potassium transport protein Kup complement(5198584..5200452) Escherichia coli O104:H4 str. 2009EL-2050 13693003 YP_006772606.1 CDS O3M_25010 NC_018650.1 5200675 5202171 D COG0714 MoxR-like ATPases; regulatory ATPase RavA 5200675..5202171 Escherichia coli O104:H4 str. 2009EL-2050 13693004 YP_006772607.1 CDS O3M_25015 NC_018650.1 5202165 5203616 D COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 5202165..5203616 Escherichia coli O104:H4 str. 2009EL-2050 13693005 YP_006772608.1 CDS O3M_25020 NC_018650.1 5203621 5204613 R COG2502 Asparagine synthetase A; asparagine synthetase AsnA complement(5203621..5204613) Escherichia coli O104:H4 str. 2009EL-2050 13693006 YP_006772609.1 CDS O3M_25025 NC_018650.1 5204765 5205223 D COG1522 Transcriptional regulators; DNA-binding transcriptional regulator AsnC 5204765..5205223 Escherichia coli O104:H4 str. 2009EL-2050 13693007 YP_006772610.1 CDS O3M_25030 NC_018650.1 5205313 5205756 D COG0716 Flavodoxins; FMN-binding protein MioC 5205313..5205756 Escherichia coli O104:H4 str. 2009EL-2050 13693008 YP_006772611.1 CDS O3M_25035 NC_018650.1 5206135 5208024 D COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 5206135..5208024 Escherichia coli O104:H4 str. 2009EL-2050 13693009 YP_006772612.1 CDS gidB NC_018650.1 5208088 5208711 D COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; 16S rRNA methyltransferase GidB 5208088..5208711 Escherichia coli O104:H4 str. 2009EL-2050 13693010 YP_006772613.1 CDS O3M_25045 NC_018650.1 5209328 5209708 D F0F1 ATP synthase subunit I 5209328..5209708 Escherichia coli O104:H4 str. 2009EL-2050 13693011 YP_006772614.1 CDS O3M_25050 NC_018650.1 5209717 5210532 D COG0356 F0F1-type ATP synthase, subunit a; F0F1 ATP synthase subunit A 5209717..5210532 Escherichia coli O104:H4 str. 2009EL-2050 13693012 YP_006772615.1 CDS O3M_25055 NC_018650.1 5210579 5210818 D COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; F0F1 ATP synthase subunit C 5210579..5210818 Escherichia coli O104:H4 str. 2009EL-2050 13693013 YP_006772616.1 CDS O3M_25060 NC_018650.1 5210880 5211350 D COG0711 F0F1-type ATP synthase, subunit b; F0F1 ATP synthase subunit B 5210880..5211350 Escherichia coli O104:H4 str. 2009EL-2050 13693014 YP_006772617.1 CDS O3M_25065 NC_018650.1 5211365 5211898 D COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); F0F1 ATP synthase subunit delta 5211365..5211898 Escherichia coli O104:H4 str. 2009EL-2050 13693015 YP_006772618.1 CDS O3M_25070 NC_018650.1 5211911 5213452 D COG0056 F0F1-type ATP synthase, alpha subunit; F0F1 ATP synthase subunit alpha 5211911..5213452 Escherichia coli O104:H4 str. 2009EL-2050 13693016 YP_006772619.1 CDS O3M_25075 NC_018650.1 5213503 5214366 D COG0224 F0F1-type ATP synthase, gamma subunit; F0F1 ATP synthase subunit gamma 5213503..5214366 Escherichia coli O104:H4 str. 2009EL-2050 13693017 YP_006772620.1 CDS O3M_25080 NC_018650.1 5214393 5215775 D COG0055 F0F1-type ATP synthase, beta subunit; F0F1 ATP synthase subunit beta 5214393..5215775 Escherichia coli O104:H4 str. 2009EL-2050 13693018 YP_006772621.1 CDS atpC NC_018650.1 5215796 5216215 D COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit); F0F1 ATP synthase subunit epsilon 5215796..5216215 Escherichia coli O104:H4 str. 2009EL-2050 13693019 YP_006772622.1 CDS glmU NC_018650.1 5216566 5217936 D COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 5216566..5217936 Escherichia coli O104:H4 str. 2009EL-2050 13693020 YP_006772623.1 CDS O3M_25095 NC_018650.1 5218098 5219927 D COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; glucosamine--fructose-6-phosphate aminotransferase 5218098..5219927 Escherichia coli O104:H4 str. 2009EL-2050 13693021 YP_006772624.1 CDS lpfA NC_018650.1 5220229 5220801 D COG3539 P pilus assembly protein, pilin FimA; fimbrial protein 5220229..5220801 Escherichia coli O104:H4 str. 2009EL-2050 13693022 YP_006772625.1 CDS lfpB NC_018650.1 5220849 5221580 D COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein 5220849..5221580 Escherichia coli O104:H4 str. 2009EL-2050 13693023 YP_006772626.1 CDS O3M_25110 NC_018650.1 5221605 5224127 D COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein 5221605..5224127 Escherichia coli O104:H4 str. 2009EL-2050 13693024 YP_006772627.1 CDS O3M_25115 NC_018650.1 5224138 5225211 D fimbrial protein 5224138..5225211 Escherichia coli O104:H4 str. 2009EL-2050 13693025 YP_006772628.1 CDS O3M_25120 NC_018650.1 5225459 5226499 D COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 5225459..5226499 Escherichia coli O104:H4 str. 2009EL-2050 13693026 YP_006772629.1 CDS pstC NC_018650.1 5226586 5227545 D COG0573 ABC-type phosphate transport system, permease component; phosphate transporter permease subunit PstC 5226586..5227545 Escherichia coli O104:H4 str. 2009EL-2050 13693027 YP_006772630.1 CDS pstA NC_018650.1 5227545 5228435 D COG0581 ABC-type phosphate transport system, permease component; phosphate transporter permease subunit PtsA 5227545..5228435 Escherichia coli O104:H4 str. 2009EL-2050 13693028 YP_006772631.1 CDS pstB NC_018650.1 5228526 5229299 D COG1117 ABC-type phosphate transport system, ATPase component; phosphate transporter ATP-binding protein 5228526..5229299 Escherichia coli O104:H4 str. 2009EL-2050 13693029 YP_006772632.1 CDS O3M_25140 NC_018650.1 5229314 5230039 D COG0704 Phosphate uptake regulator; transcriptional regulator PhoU 5229314..5230039 Escherichia coli O104:H4 str. 2009EL-2050 13693030 YP_006772633.1 CDS O3M_25145 NC_018650.1 5230325 5230768 D COG3711 Transcriptional antiterminator; transcriptional antiterminator BglG 5230325..5230768 Escherichia coli O104:H4 str. 2009EL-2050 13693031 YP_006772634.1 CDS O3M_25150 NC_018650.1 5230784 5231161 D COG3711 Transcriptional antiterminator; transcriptional antiterminator BglG 5230784..5231161 Escherichia coli O104:H4 str. 2009EL-2050 13693032 YP_006772635.1 CDS O3M_25155 NC_018650.1 5231295 5233172 D COG1264 Phosphotransferase system IIB components; PTS system beta-glucoside-specific transporter subunit IIABC 5231295..5233172 Escherichia coli O104:H4 str. 2009EL-2050 13693033 YP_006772636.1 CDS O3M_25160 NC_018650.1 5233191 5234585 D COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; cryptic phospho-beta-glucosidase B 5233191..5234585 Escherichia coli O104:H4 str. 2009EL-2050 13693034 YP_006772637.1 CDS O3M_25165 NC_018650.1 5234671 5236287 D COG4580 Maltoporin (phage lambda and maltose receptor); carbohydrate-specific outer membrane porin, cryptic 5234671..5236287 Escherichia coli O104:H4 str. 2009EL-2050 13693035 YP_006772638.1 CDS O3M_25170 NC_018650.1 5236314 5237483 D COG2382 Enterochelin esterase and related enzymes; xylanase 5236314..5237483 Escherichia coli O104:H4 str. 2009EL-2050 13693036 YP_006772639.1 CDS O3M_25175 NC_018650.1 5237498 5238220 D COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; 6-phosphogluconolactonase 5237498..5238220 Escherichia coli O104:H4 str. 2009EL-2050 13693037 YP_006772640.1 CDS O3M_25180 NC_018650.1 5238282 5238869 R COG3196 Uncharacterized protein conserved in bacteria; hypothetical protein complement(5238282..5238869) Escherichia coli O104:H4 str. 2009EL-2050 13693038 YP_006772641.1 CDS O3M_25185 NC_018650.1 5238918 5239391 R inner membrane protein complement(5238918..5239391) Escherichia coli O104:H4 str. 2009EL-2050 13693039 YP_006772642.1 CDS O3M_25190 NC_018650.1 5239458 5240123 R COG0637 Predicted phosphatase/phosphohexomutase; 6-phosphogluconate phosphatase complement(5239458..5240123) Escherichia coli O104:H4 str. 2009EL-2050 13693040 YP_006772643.1 CDS O3M_25195 NC_018650.1 5240290 5241627 D COG2252 Permeases; hypothetical protein 5240290..5241627 Escherichia coli O104:H4 str. 2009EL-2050 13693041 YP_006772644.1 CDS O3M_25200 NC_018650.1 5241681 5242247 R COG0431 Predicted flavoprotein; hypothetical protein complement(5241681..5242247) Escherichia coli O104:H4 str. 2009EL-2050 13693042 YP_006772645.1 CDS O3M_25205 NC_018650.1 5242269 5243018 R COG2091 Phosphopantetheinyl transferase; phosphopantetheinyl transferase complement(5242269..5243018) Escherichia coli O104:H4 str. 2009EL-2050 13693043 YP_006772646.1 CDS O3M_25210 NC_018650.1 5243175 5244134 R COG0583 Transcriptional regulator; DNA-binding transcriptional regulator YidZ complement(5243175..5244134) Escherichia coli O104:H4 str. 2009EL-2050 13693044 YP_006772647.1 CDS O3M_25215 NC_018650.1 5244109 5245284 R COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein MdtL complement(5244109..5245284) Escherichia coli O104:H4 str. 2009EL-2050 13693045 YP_006772648.1 CDS O3M_25220 NC_018650.1 5245417 5246664 R COG0814 Amino acid permeases; tryptophan permease TnaB complement(5245417..5246664) Escherichia coli O104:H4 str. 2009EL-2050 13693046 YP_006772649.1 CDS tnaA NC_018650.1 5246755 5248170 R COG3033 Tryptophanase; tryptophanase/L-cysteine desulfhydrase, PLP-dependent complement(5246755..5248170) Escherichia coli O104:H4 str. 2009EL-2050 13693047 YP_006772650.1 CDS O3M_25230 NC_018650.1 5248391 5248465 R tryptophanase leader peptide complement(5248391..5248465) Escherichia coli O104:H4 str. 2009EL-2050 13693048 YP_006772651.1 CDS trmE NC_018650.1 5248708 5250072 R COG0486 Predicted GTPase; tRNA modification GTPase TrmE complement(5248708..5250072) Escherichia coli O104:H4 str. 2009EL-2050 13693049 YP_006772652.1 CDS O3M_25240 NC_018650.1 5250178 5251824 R COG0706 Preprotein translocase subunit YidC; membrane protein insertase complement(5250178..5251824) Escherichia coli O104:H4 str. 2009EL-2050 13693050 YP_006772653.1 CDS O3M_25245 NC_018650.1 5251827 5252084 R COG0759 Uncharacterized conserved protein; hypothetical protein complement(5251827..5252084) Escherichia coli O104:H4 str. 2009EL-2050 13693051 YP_006772654.1 CDS rnpA NC_018650.1 5252048 5252407 R COG0594 RNase P protein component; ribonuclease P complement(5252048..5252407) Escherichia coli O104:H4 str. 2009EL-2050 13693052 YP_006772655.1 CDS rpmH NC_018650.1 5252424 5252564 R COG0230 Ribosomal protein L34; 50S ribosomal protein L34 complement(5252424..5252564) Escherichia coli O104:H4 str. 2009EL-2050 13693053 YP_006772656.1 CDS O3M_25494 NC_018651.1 108212 3500 R COG0840 Methyl-accepting chemotaxis protein; phage tail tape measure protein complement(join(108212..109274,1..3500)) Escherichia coli O104:H4 str. 2009EL-2050 13693762 YP_006772657.1 CDS O3M_25499 NC_018651.1 3508 3777 R hypothetical protein complement(3508..3777) Escherichia coli O104:H4 str. 2009EL-2050 13693763 YP_006772658.1 CDS O3M_25504 NC_018651.1 3858 4175 R hypothetical protein complement(3858..4175) Escherichia coli O104:H4 str. 2009EL-2050 13693764 YP_006772659.1 CDS O3M_25509 NC_018651.1 4243 4980 R COG5492 Bacterial surface proteins containing Ig-like domains; hypothetical protein complement(4243..4980) Escherichia coli O104:H4 str. 2009EL-2050 13693765 YP_006772660.1 CDS O3M_25514 NC_018651.1 5054 5437 R hypothetical protein complement(5054..5437) Escherichia coli O104:H4 str. 2009EL-2050 13693766 YP_006772661.1 CDS O3M_25519 NC_018651.1 5439 5912 R hypothetical protein complement(5439..5912) Escherichia coli O104:H4 str. 2009EL-2050 13693767 YP_006772662.1 CDS O3M_25524 NC_018651.1 5903 6247 R hypothetical protein complement(5903..6247) Escherichia coli O104:H4 str. 2009EL-2050 13693768 YP_006772663.1 CDS O3M_25529 NC_018651.1 6319 7152 R hypothetical protein complement(6319..7152) Escherichia coli O104:H4 str. 2009EL-2050 13693769 YP_006772664.1 CDS O3M_25534 NC_018651.1 7152 7586 R hypothetical protein complement(7152..7586) Escherichia coli O104:H4 str. 2009EL-2050 13693770 YP_006772665.1 CDS O3M_25539 NC_018651.1 7684 8604 R hypothetical protein complement(7684..8604) Escherichia coli O104:H4 str. 2009EL-2050 13693771 YP_006772666.1 CDS O3M_25544 NC_018651.1 8630 9517 R hypothetical protein complement(8630..9517) Escherichia coli O104:H4 str. 2009EL-2050 13693772 YP_006772667.1 CDS O3M_25549 NC_018651.1 9539 11113 R hypothetical protein complement(9539..11113) Escherichia coli O104:H4 str. 2009EL-2050 13693773 YP_006772668.1 CDS O3M_25554 NC_018651.1 11140 12396 R hypothetical protein complement(11140..12396) Escherichia coli O104:H4 str. 2009EL-2050 13693774 YP_006772669.1 CDS O3M_25559 NC_018651.1 12396 13028 R DNA-binding protein complement(12396..13028) Escherichia coli O104:H4 str. 2009EL-2050 13693775 YP_006772670.1 CDS O3M_25564 NC_018651.1 13224 13490 R hypothetical protein complement(13224..13490) Escherichia coli O104:H4 str. 2009EL-2050 13693776 YP_006772671.1 CDS O3M_25569 NC_018651.1 13500 14390 R COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain; hypothetical protein complement(13500..14390) Escherichia coli O104:H4 str. 2009EL-2050 13693777 YP_006772672.1 CDS O3M_25574 NC_018651.1 14387 15052 R COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain; ABC transporter ATP-binding protein complement(14387..15052) Escherichia coli O104:H4 str. 2009EL-2050 13693778 YP_006772673.1 CDS O3M_25579 NC_018651.1 15049 15717 R COG1475 Predicted transcriptional regulators; hypothetical protein complement(15049..15717) Escherichia coli O104:H4 str. 2009EL-2050 13693779 YP_006772674.1 CDS O3M_25584 NC_018651.1 15717 16415 R COG1475 Predicted transcriptional regulators; hypothetical protein complement(15717..16415) Escherichia coli O104:H4 str. 2009EL-2050 13693780 YP_006772675.1 CDS O3M_25589 NC_018651.1 16480 18039 D COG1061 DNA or RNA helicases of superfamily II; helicase 16480..18039 Escherichia coli O104:H4 str. 2009EL-2050 13693781 YP_006772676.1 CDS O3M_25594 NC_018651.1 18042 18320 D hypothetical protein 18042..18320 Escherichia coli O104:H4 str. 2009EL-2050 13693782 YP_006772677.1 CDS O3M_25599 NC_018651.1 18386 18952 D hypothetical protein 18386..18952 Escherichia coli O104:H4 str. 2009EL-2050 13693783 YP_006772678.1 CDS O3M_25604 NC_018651.1 19098 19586 D hypothetical protein 19098..19586 Escherichia coli O104:H4 str. 2009EL-2050 13693784 YP_006772679.1 CDS O3M_25609 NC_018651.1 19602 20201 D COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; hypothetical protein 19602..20201 Escherichia coli O104:H4 str. 2009EL-2050 13693785 YP_006772680.1 CDS O3M_25614 NC_018651.1 20198 20722 D transcriptional regulator 20198..20722 Escherichia coli O104:H4 str. 2009EL-2050 13693786 YP_006772681.1 CDS O3M_25619 NC_018651.1 21011 21661 D hypothetical protein 21011..21661 Escherichia coli O104:H4 str. 2009EL-2050 13693787 YP_006772682.1 CDS O3M_25624 NC_018651.1 21710 21913 D hypothetical protein 21710..21913 Escherichia coli O104:H4 str. 2009EL-2050 13693788 YP_006772683.1 CDS O3M_25629 NC_018651.1 21935 22165 D hypothetical protein 21935..22165 Escherichia coli O104:H4 str. 2009EL-2050 13693789 YP_006772684.1 CDS O3M_25634 NC_018651.1 22781 23263 R hypothetical protein complement(22781..23263) Escherichia coli O104:H4 str. 2009EL-2050 13693790 YP_006772685.1 CDS O3M_25639 NC_018651.1 23614 23988 R hypothetical protein complement(23614..23988) Escherichia coli O104:H4 str. 2009EL-2050 13693791 YP_006772686.1 CDS O3M_25644 NC_018651.1 24107 24502 R hypothetical protein complement(24107..24502) Escherichia coli O104:H4 str. 2009EL-2050 13693792 YP_006772687.1 CDS O3M_25649 NC_018651.1 24629 24940 R hypothetical protein complement(24629..24940) Escherichia coli O104:H4 str. 2009EL-2050 13693793 YP_006772688.1 CDS O3M_25654 NC_018651.1 25095 25424 R hypothetical protein complement(25095..25424) Escherichia coli O104:H4 str. 2009EL-2050 13693794 YP_006772689.1 CDS O3M_25659 NC_018651.1 25563 25781 R hypothetical protein complement(25563..25781) Escherichia coli O104:H4 str. 2009EL-2050 13693795 YP_006772690.1 CDS O3M_25664 NC_018651.1 27322 27507 R hypothetical protein complement(27322..27507) Escherichia coli O104:H4 str. 2009EL-2050 13693796 YP_006772691.1 CDS O3M_25669 NC_018651.1 27544 27843 R hypothetical protein complement(27544..27843) Escherichia coli O104:H4 str. 2009EL-2050 13693797 YP_006772692.1 CDS metG NC_018651.1 28005 30038 R COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase complement(28005..30038) Escherichia coli O104:H4 str. 2009EL-2050 13693798 YP_006772693.1 CDS O3M_25679 NC_018651.1 30196 31296 D COG0489 ATPases involved in chromosome partitioning; antiporter inner membrane protein 30196..31296 Escherichia coli O104:H4 str. 2009EL-2050 13693799 YP_006772694.1 CDS O3M_25684 NC_018651.1 31334 31723 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); DNA repair protein complement(31334..31723) Escherichia coli O104:H4 str. 2009EL-2050 13693800 YP_006772695.1 CDS O3M_25689 NC_018651.1 31896 32459 R hypothetical protein complement(31896..32459) Escherichia coli O104:H4 str. 2009EL-2050 13693801 YP_006772696.1 CDS O3M_25694 NC_018651.1 32434 33285 R phage protein complement(32434..33285) Escherichia coli O104:H4 str. 2009EL-2050 13693802 YP_006772697.1 CDS O3M_25699 NC_018651.1 33285 33506 R hypothetical protein complement(33285..33506) Escherichia coli O104:H4 str. 2009EL-2050 13693803 YP_006772698.1 CDS O3M_25704 NC_018651.1 33499 34074 R Eaa protein complement(33499..34074) Escherichia coli O104:H4 str. 2009EL-2050 13693804 YP_006772699.1 CDS O3M_25709 NC_018651.1 34076 34462 R hypothetical protein complement(34076..34462) Escherichia coli O104:H4 str. 2009EL-2050 13693805 YP_006772700.1 CDS O3M_25714 NC_018651.1 34473 34736 R hypothetical protein complement(34473..34736) Escherichia coli O104:H4 str. 2009EL-2050 13693806 YP_006772701.1 CDS O3M_25719 NC_018651.1 34738 35259 R hypothetical protein complement(34738..35259) Escherichia coli O104:H4 str. 2009EL-2050 13693807 YP_006772702.1 CDS clpX NC_018651.1 35256 35579 R COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease ATP-binding subunit ClpX complement(35256..35579) Escherichia coli O104:H4 str. 2009EL-2050 13693808 YP_006772703.1 CDS O3M_25729 NC_018651.1 35581 36111 R COG1196 Chromosome segregation ATPases; hypothetical protein complement(35581..36111) Escherichia coli O104:H4 str. 2009EL-2050 13693809 YP_006772704.1 CDS O3M_25734 NC_018651.1 36098 36352 R hypothetical protein complement(36098..36352) Escherichia coli O104:H4 str. 2009EL-2050 13693810 YP_006772705.1 CDS O3M_25739 NC_018651.1 36349 36891 R hypothetical protein complement(36349..36891) Escherichia coli O104:H4 str. 2009EL-2050 13693811 YP_006772706.1 CDS O3M_25744 NC_018651.1 37030 37410 R hypothetical protein complement(37030..37410) Escherichia coli O104:H4 str. 2009EL-2050 13693812 YP_006772707.1 CDS O3M_25749 NC_018651.1 37410 38114 R hypothetical protein complement(37410..38114) Escherichia coli O104:H4 str. 2009EL-2050 13693813 YP_006772708.1 CDS O3M_25754 NC_018651.1 38176 39861 R COG0827 Adenine-specific DNA methylase; DNA modification methylase complement(38176..39861) Escherichia coli O104:H4 str. 2009EL-2050 13693814 YP_006772709.1 CDS O3M_25759 NC_018651.1 39965 40579 R hypothetical protein complement(39965..40579) Escherichia coli O104:H4 str. 2009EL-2050 13693815 YP_006772710.1 CDS O3M_25764 NC_018651.1 40921 41490 R hypothetical protein complement(40921..41490) Escherichia coli O104:H4 str. 2009EL-2050 13693816 YP_006772711.1 CDS O3M_25769 NC_018651.1 41630 41788 R hypothetical protein complement(41630..41788) Escherichia coli O104:H4 str. 2009EL-2050 13693817 YP_006772712.1 CDS O3M_25774 NC_018651.1 41788 42213 R COG3793 Tellurite resistance protein; hypothetical protein complement(41788..42213) Escherichia coli O104:H4 str. 2009EL-2050 13693818 YP_006772713.1 CDS O3M_25779 NC_018651.1 42307 42495 R hypothetical protein complement(42307..42495) Escherichia coli O104:H4 str. 2009EL-2050 13693819 YP_006772714.1 CDS O3M_25784 NC_018651.1 42492 42743 R hypothetical protein complement(42492..42743) Escherichia coli O104:H4 str. 2009EL-2050 13693820 YP_006772715.1 CDS O3M_25789 NC_018651.1 43145 43738 R COG0328 Ribonuclease HI; ribonuclease H complement(43145..43738) Escherichia coli O104:H4 str. 2009EL-2050 13693821 YP_006772716.1 CDS O3M_25794 NC_018651.1 44320 44550 R hypothetical protein complement(44320..44550) Escherichia coli O104:H4 str. 2009EL-2050 13693822 YP_006772717.1 CDS O3M_25799 NC_018651.1 44738 45331 R hypothetical protein complement(44738..45331) Escherichia coli O104:H4 str. 2009EL-2050 13693823 YP_006772718.1 CDS O3M_25804 NC_018651.1 45514 46323 R hypothetical protein complement(45514..46323) Escherichia coli O104:H4 str. 2009EL-2050 13693824 YP_006772719.1 CDS O3M_25809 NC_018651.1 46484 47041 R COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; hypothetical protein complement(46484..47041) Escherichia coli O104:H4 str. 2009EL-2050 13693825 YP_006772720.1 CDS O3M_25814 NC_018651.1 47051 47470 R hypothetical protein complement(47051..47470) Escherichia coli O104:H4 str. 2009EL-2050 13693826 YP_006772721.1 CDS O3M_25819 NC_018651.1 47532 48176 R COG0563 Adenylate kinase and related kinases; hypothetical protein complement(47532..48176) Escherichia coli O104:H4 str. 2009EL-2050 13693827 YP_006772722.1 CDS O3M_25824 NC_018651.1 48176 48652 R COG0262 Dihydrofolate reductase; dihydrofolate reductase complement(48176..48652) Escherichia coli O104:H4 str. 2009EL-2050 13693828 YP_006772723.1 CDS O3M_25829 NC_018651.1 48649 49050 R COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain; hypothetical protein complement(48649..49050) Escherichia coli O104:H4 str. 2009EL-2050 13693829 YP_006772724.1 CDS O3M_25834 NC_018651.1 49064 50167 R COG0207 Thymidylate synthase; thymidylate synthase complement(49064..50167) Escherichia coli O104:H4 str. 2009EL-2050 13693830 YP_006772725.1 CDS O3M_25839 NC_018651.1 50335 51204 R hypothetical protein complement(50335..51204) Escherichia coli O104:H4 str. 2009EL-2050 13693831 YP_006772726.1 CDS nrdB NC_018651.1 51282 52424 R COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta complement(51282..52424) Escherichia coli O104:H4 str. 2009EL-2050 13693703 YP_006772727.1 CDS O3M_25849 NC_018651.1 52533 54848 R COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha complement(52533..54848) Escherichia coli O104:H4 str. 2009EL-2050 13693704 YP_006772728.1 CDS O3M_25854 NC_018651.1 54922 55491 R COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit; hypothetical protein complement(54922..55491) Escherichia coli O104:H4 str. 2009EL-2050 13693705 YP_006772729.1 CDS O3M_25859 NC_018651.1 55501 56244 R hypothetical protein complement(55501..56244) Escherichia coli O104:H4 str. 2009EL-2050 13693706 YP_006772730.1 CDS O3M_25864 NC_018651.1 56234 58150 R COG0419 ATPase involved in DNA repair; exonuclease subunit 2 complement(56234..58150) Escherichia coli O104:H4 str. 2009EL-2050 13693707 YP_006772731.1 CDS O3M_25869 NC_018651.1 58380 59465 R COG0420 DNA repair exonuclease; hypothetical protein complement(58380..59465) Escherichia coli O104:H4 str. 2009EL-2050 13693708 YP_006772732.1 CDS O3M_25874 NC_018651.1 59720 60364 R hypothetical protein complement(59720..60364) Escherichia coli O104:H4 str. 2009EL-2050 13693709 YP_006772733.1 CDS O3M_25879 NC_018651.1 60686 61780 D RepA/RepC 60686..61780 Escherichia coli O104:H4 str. 2009EL-2050 13693710 YP_006772734.1 CDS O3M_25884 NC_018651.1 62360 62572 R hypothetical protein complement(62360..62572) Escherichia coli O104:H4 str. 2009EL-2050 13693711 YP_006772735.1 CDS O3M_25889 NC_018651.1 62572 62907 R hypothetical protein complement(62572..62907) Escherichia coli O104:H4 str. 2009EL-2050 13693712 YP_006772736.1 CDS O3M_25894 NC_018651.1 62904 63083 R hypothetical protein complement(62904..63083) Escherichia coli O104:H4 str. 2009EL-2050 13693713 YP_006772737.1 CDS O3M_25899 NC_018651.1 63123 63398 R hypothetical protein complement(63123..63398) Escherichia coli O104:H4 str. 2009EL-2050 13693714 YP_006772738.1 CDS O3M_25904 NC_018651.1 63454 63879 R hypothetical protein complement(63454..63879) Escherichia coli O104:H4 str. 2009EL-2050 13693715 YP_006772739.1 CDS O3M_25909 NC_018651.1 63941 64330 R hypothetical protein complement(63941..64330) Escherichia coli O104:H4 str. 2009EL-2050 13693716 YP_006772740.1 CDS O3M_25914 NC_018651.1 64351 65091 R hypothetical protein complement(64351..65091) Escherichia coli O104:H4 str. 2009EL-2050 13693717 YP_006772741.1 CDS O3M_25919 NC_018651.1 65139 65963 R hypothetical protein complement(65139..65963) Escherichia coli O104:H4 str. 2009EL-2050 13693718 YP_006772742.1 CDS O3M_25924 NC_018651.1 66059 66889 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; lipoprotein complement(66059..66889) Escherichia coli O104:H4 str. 2009EL-2050 13693719 YP_006772743.1 CDS O3M_25929 NC_018651.1 66893 67093 R hypothetical protein complement(66893..67093) Escherichia coli O104:H4 str. 2009EL-2050 13693720 YP_006772744.1 CDS O3M_25934 NC_018651.1 67186 68259 R COG0468 RecA/RadA recombinase; recombinase complement(67186..68259) Escherichia coli O104:H4 str. 2009EL-2050 13693721 YP_006772745.1 CDS O3M_25939 NC_018651.1 68262 68528 R hypothetical protein complement(68262..68528) Escherichia coli O104:H4 str. 2009EL-2050 13693722 YP_006772746.1 CDS O3M_25944 NC_018651.1 68528 69472 R COG0258 5'-3' exonuclease (including N-terminal domain of PolI); exonuclease complement(68528..69472) Escherichia coli O104:H4 str. 2009EL-2050 13693723 YP_006772747.1 CDS O3M_25949 NC_018651.1 69533 70561 R regulator complement(69533..70561) Escherichia coli O104:H4 str. 2009EL-2050 13693724 YP_006772748.1 CDS O3M_25954 NC_018651.1 70679 71110 R hypothetical protein complement(70679..71110) Escherichia coli O104:H4 str. 2009EL-2050 13693725 YP_006772749.1 CDS O3M_25959 NC_018651.1 71236 74754 R COG0587 DNA polymerase III, alpha subunit; DNA polymerase III complement(71236..74754) Escherichia coli O104:H4 str. 2009EL-2050 13693726 YP_006772750.1 CDS O3M_25964 NC_018651.1 74935 76170 R COG0714 MoxR-like ATPases; porphyrin biosynthetic protein complement(74935..76170) Escherichia coli O104:H4 str. 2009EL-2050 13693727 YP_006772751.1 CDS O3M_25969 NC_018651.1 76266 78374 R COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase); porphyrin biosynthetic protein complement(76266..78374) Escherichia coli O104:H4 str. 2009EL-2050 13693728 YP_006772752.1 CDS O3M_25974 NC_018651.1 78475 78687 R hypothetical protein complement(78475..78687) Escherichia coli O104:H4 str. 2009EL-2050 13693729 YP_006772753.1 CDS O3M_25979 NC_018651.1 78935 79321 D hypothetical protein 78935..79321 Escherichia coli O104:H4 str. 2009EL-2050 13693730 YP_006772754.1 CDS O3M_25984 NC_018651.1 79316 80419 R COG0582 Integrase; integrase complement(79316..80419) Escherichia coli O104:H4 str. 2009EL-2050 13693731 YP_006772755.1 CDS O3M_25989 NC_018651.1 80627 82540 R hypothetical protein complement(80627..82540) Escherichia coli O104:H4 str. 2009EL-2050 13693732 YP_006772756.1 CDS O3M_25999 NC_018651.1 84366 84656 R hypothetical protein complement(84366..84656) Escherichia coli O104:H4 str. 2009EL-2050 13693737 YP_006772757.1 CDS O3M_26004 NC_018651.1 84653 84805 R hypothetical protein complement(84653..84805) Escherichia coli O104:H4 str. 2009EL-2050 13693738 YP_006772758.1 CDS O3M_26009 NC_018651.1 84802 85017 R hypothetical protein complement(84802..85017) Escherichia coli O104:H4 str. 2009EL-2050 13693739 YP_006772759.1 CDS O3M_26014 NC_018651.1 85001 85180 R hypothetical protein complement(85001..85180) Escherichia coli O104:H4 str. 2009EL-2050 13693740 YP_006772760.1 CDS O3M_26019 NC_018651.1 85177 86499 R DNA ligase complement(85177..86499) Escherichia coli O104:H4 str. 2009EL-2050 13693741 YP_006772761.1 CDS O3M_26024 NC_018651.1 86496 86753 R hypothetical protein complement(86496..86753) Escherichia coli O104:H4 str. 2009EL-2050 13693742 YP_006772762.1 CDS O3M_26029 NC_018651.1 87034 87816 R hypothetical protein complement(87034..87816) Escherichia coli O104:H4 str. 2009EL-2050 13693743 YP_006772763.1 CDS O3M_26034 NC_018651.1 87892 89073 R COG0358 DNA primase (bacterial type); hypothetical protein complement(87892..89073) Escherichia coli O104:H4 str. 2009EL-2050 13693744 YP_006772764.1 CDS O3M_26039 NC_018651.1 89155 90495 R COG0305 Replicative DNA helicase; DNA helicase complement(89155..90495) Escherichia coli O104:H4 str. 2009EL-2050 13693745 YP_006772765.1 CDS O3M_26044 NC_018651.1 90539 91279 R hypothetical protein complement(90539..91279) Escherichia coli O104:H4 str. 2009EL-2050 13693746 YP_006772766.1 CDS O3M_26049 NC_018651.1 91460 93154 R hypothetical protein complement(91460..93154) Escherichia coli O104:H4 str. 2009EL-2050 13693747 YP_006772767.1 CDS O3M_26054 NC_018651.1 93206 93565 R hypothetical protein complement(93206..93565) Escherichia coli O104:H4 str. 2009EL-2050 13693748 YP_006772768.1 CDS O3M_26059 NC_018651.1 93565 94233 R COG1192 ATPases involved in chromosome partitioning; hypothetical protein complement(93565..94233) Escherichia coli O104:H4 str. 2009EL-2050 13693749 YP_006772769.1 CDS O3M_26064 NC_018651.1 94552 94821 D COG4453 Uncharacterized protein conserved in bacteria; hypothetical protein 94552..94821 Escherichia coli O104:H4 str. 2009EL-2050 13693750 YP_006772770.1 CDS O3M_26069 NC_018651.1 94829 95350 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 94829..95350 Escherichia coli O104:H4 str. 2009EL-2050 13693751 YP_006772771.1 CDS O3M_26074 NC_018651.1 95518 95769 R hypothetical protein complement(95518..95769) Escherichia coli O104:H4 str. 2009EL-2050 13693752 YP_006772772.1 CDS O3M_26079 NC_018651.1 95771 96463 R hypothetical protein complement(95771..96463) Escherichia coli O104:H4 str. 2009EL-2050 13693753 YP_006772773.1 CDS O3M_26084 NC_018651.1 96477 96800 R hypothetical protein complement(96477..96800) Escherichia coli O104:H4 str. 2009EL-2050 13693754 YP_006772774.1 CDS O3M_26089 NC_018651.1 96898 97410 R hypothetical protein complement(96898..97410) Escherichia coli O104:H4 str. 2009EL-2050 13693755 YP_006772775.1 CDS O3M_26094 NC_018651.1 97496 100867 R phage lambda-related protein complement(97496..100867) Escherichia coli O104:H4 str. 2009EL-2050 13693756 YP_006772776.1 CDS O3M_26099 NC_018651.1 100962 105668 R COG4733 Phage-related protein, tail component; phage tail protein complement(100962..105668) Escherichia coli O104:H4 str. 2009EL-2050 13693757 YP_006772777.1 CDS O3M_26104 NC_018651.1 105685 106275 R COG4723 Phage-related protein, tail component; phage tail protein complement(105685..106275) Escherichia coli O104:H4 str. 2009EL-2050 13693758 YP_006772778.1 CDS O3M_26109 NC_018651.1 106263 107060 R COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; phage tail protein complement(106263..107060) Escherichia coli O104:H4 str. 2009EL-2050 13693759 YP_006772779.1 CDS O3M_26114 NC_018651.1 107053 107751 R COG4672 Phage-related protein; phage lambda-related tail protein L complement(107053..107751) Escherichia coli O104:H4 str. 2009EL-2050 13693760 YP_006772780.1 CDS O3M_26119 NC_018651.1 107834 108169 R COG4718 Phage-related protein; minor tail fiber protein M complement(107834..108169) Escherichia coli O104:H4 str. 2009EL-2050 13693761 YP_006772781.1 CDS O3M_26617 NC_018652.1 3 515 D replication protein 3..515 Escherichia coli O104:H4 str. 2009EL-2050 13696061 YP_006772782.1 CDS O3M_26622 NC_018652.1 571 1047 R COG4565 Response regulator of citrate/malate metabolism; plasmid replication protein complement(571..1047) Escherichia coli O104:H4 str. 2009EL-2050 13696060 YP_006772784.1 CDS O3M_26612 NC_018654.1 73478 71 D COG0582 Integrase; resolvase (protein D) join(73478..74213,1..71) Escherichia coli O104:H4 str. 2009EL-2050 13696106 YP_006772785.1 CDS O3M_26137 NC_018654.1 250 894 D COG1192 ATPases involved in chromosome partitioning; chromosome partitioning ATPase 250..894 Escherichia coli O104:H4 str. 2009EL-2050 13696105 YP_006772786.1 CDS O3M_26142 NC_018654.1 981 1289 D chaperonin 981..1289 Escherichia coli O104:H4 str. 2009EL-2050 13696107 YP_006772787.1 CDS O3M_26147 NC_018654.1 1703 2683 D COG0443 Molecular chaperone; Plasmid segregation protein (ParA locus) 1703..2683 Escherichia coli O104:H4 str. 2009EL-2050 13696108 YP_006772788.1 CDS O3M_26152 NC_018654.1 2676 3092 D hypothetical protein 2676..3092 Escherichia coli O104:H4 str. 2009EL-2050 13696109 YP_006772789.1 CDS umuC NC_018654.1 3172 3330 R COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC complement(3172..3330) Escherichia coli O104:H4 str. 2009EL-2050 13696110 YP_006772790.1 CDS umuC NC_018654.1 3468 4367 R COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC complement(3468..4367) Escherichia coli O104:H4 str. 2009EL-2050 13696111 YP_006772791.1 CDS O3M_26167 NC_018654.1 4367 4744 R COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); UV protection protein complement(4367..4744) Escherichia coli O104:H4 str. 2009EL-2050 13696112 YP_006772792.1 CDS O3M_26172 NC_018654.1 4831 5442 D COG1961 Site-specific recombinases, DNA invertase Pin homologs; resolvase 4831..5442 Escherichia coli O104:H4 str. 2009EL-2050 13696113 YP_006772793.1 CDS O3M_26177 NC_018654.1 5941 6144 D hypothetical protein 5941..6144 Escherichia coli O104:H4 str. 2009EL-2050 13696114 YP_006772794.1 CDS O3M_26182 NC_018654.1 6279 7037 D COG3121 P pilus assembly protein, chaperone PapD; Chaperone protein Agg3D 6279..7037 Escherichia coli O104:H4 str. 2009EL-2050 13696115 YP_006772795.1 CDS O3M_26187 NC_018654.1 7195 9579 D COG3188 P pilus assembly protein, porin PapC; Outer membrane usher protein Agg3C 7195..9579 Escherichia coli O104:H4 str. 2009EL-2050 13696116 YP_006772796.1 CDS O3M_26192 NC_018654.1 9593 10030 D Protein Agg3B, putative invasin 9593..10030 Escherichia coli O104:H4 str. 2009EL-2050 13696117 YP_006772797.1 CDS O3M_26197 NC_018654.1 10132 10635 D hypothetical protein 10132..10635 Escherichia coli O104:H4 str. 2009EL-2050 13696118 YP_006772798.1 CDS O3M_26202 NC_018654.1 10772 11092 D COG4584 Transposase and inactivated derivatives; transposase 10772..11092 Escherichia coli O104:H4 str. 2009EL-2050 13696119 YP_006772799.1 CDS O3M_26207 NC_018654.1 11061 11222 R COG3464 Transposase and inactivated derivatives; hypothetical protein complement(11061..11222) Escherichia coli O104:H4 str. 2009EL-2050 13696120 YP_006772800.1 CDS O3M_26212 NC_018654.1 11408 11809 D COG2963 Transposase and inactivated derivatives; hypothetical protein 11408..11809 Escherichia coli O104:H4 str. 2009EL-2050 13696121 YP_006772801.1 CDS O3M_26217 NC_018654.1 11806 12153 D COG3436 Transposase and inactivated derivatives; transposase 11806..12153 Escherichia coli O104:H4 str. 2009EL-2050 13696122 YP_006772802.1 CDS O3M_26222 NC_018654.1 12203 12451 D COG2202 FOG: PAS/PAC domain; hypothetical protein 12203..12451 Escherichia coli O104:H4 str. 2009EL-2050 13696123 YP_006772803.1 CDS O3M_26227 NC_018654.1 12453 13742 D COG3436 Transposase and inactivated derivatives; protein encoded within IS 12453..13742 Escherichia coli O104:H4 str. 2009EL-2050 13696124 YP_006772804.1 CDS O3M_26232 NC_018654.1 13776 14033 R COG2801 Transposase and inactivated derivatives; ISEhe3 orfB complement(13776..14033) Escherichia coli O104:H4 str. 2009EL-2050 13696125 YP_006772805.1 CDS O3M_26237 NC_018654.1 14078 14302 D COG2801 Transposase and inactivated derivatives; hypothetical protein 14078..14302 Escherichia coli O104:H4 str. 2009EL-2050 13696126 YP_006772806.1 CDS O3M_26242 NC_018654.1 14327 14515 R COG2801 Transposase and inactivated derivatives; IS150 ORF B; transposase complement(14327..14515) Escherichia coli O104:H4 str. 2009EL-2050 13696127 YP_006772807.1 CDS O3M_26247 NC_018654.1 14758 15258 R COG2963 Transposase and inactivated derivatives; ISRSO11-transposase orfA protein complement(14758..15258) Escherichia coli O104:H4 str. 2009EL-2050 13696128 YP_006772808.1 CDS O3M_26257 NC_018654.1 15694 16722 D hypothetical protein 15694..16722 Escherichia coli O104:H4 str. 2009EL-2050 13696129 YP_006772809.1 CDS O3M_26262 NC_018654.1 16745 16969 D hypothetical protein 16745..16969 Escherichia coli O104:H4 str. 2009EL-2050 13696130 YP_006772810.1 CDS O3M_26267 NC_018654.1 16978 17265 D IPP isomerase: Isopentenyl pyrophosphate isomerase; IPP:DMAPP isomerase; COG1443 Isopentenyldiphosphate isomerase; isopentenyl-diphosphate delta-isomerase 16978..17265 Escherichia coli O104:H4 str. 2009EL-2050 13696131 YP_006772811.1 CDS O3M_26272 NC_018654.1 17768 17920 R hypothetical protein complement(17768..17920) Escherichia coli O104:H4 str. 2009EL-2050 13696132 YP_006772812.1 CDS O3M_26277 NC_018654.1 17920 18081 R hypothetical protein complement(17920..18081) Escherichia coli O104:H4 str. 2009EL-2050 13696133 YP_006772813.1 CDS O3M_26282 NC_018654.1 18080 19060 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 18080..19060 Escherichia coli O104:H4 str. 2009EL-2050 13696134 YP_006772814.1 CDS O3M_26287 NC_018654.1 19422 20246 D COG3547 Transposase and inactivated derivatives; transposase 19422..20246 Escherichia coli O104:H4 str. 2009EL-2050 13696135 YP_006772815.1 CDS O3M_26292 NC_018654.1 20489 20743 R COG2963 Transposase and inactivated derivatives; IS1; transposase ORF A, IS1 complement(20489..20743) Escherichia coli O104:H4 str. 2009EL-2050 13696136 YP_006772816.1 CDS O3M_26297 NC_018654.1 20994 21791 R COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator aggR (AAF-III) regulatory protein complement(20994..21791) Escherichia coli O104:H4 str. 2009EL-2050 13696137 YP_006772817.1 CDS O3M_26307 NC_018654.1 22525 22851 D COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein 22525..22851 Escherichia coli O104:H4 str. 2009EL-2050 13696138 YP_006772818.1 CDS O3M_26312 NC_018654.1 22848 23237 D COG2801 Transposase and inactivated derivatives; IS629 transposase OrfB 22848..23237 Escherichia coli O104:H4 str. 2009EL-2050 13696139 YP_006772819.1 CDS O3M_26317 NC_018654.1 23140 23307 D COG2801 Transposase and inactivated derivatives; transposase 23140..23307 Escherichia coli O104:H4 str. 2009EL-2050 13696140 YP_006772820.1 CDS O3M_26322 NC_018654.1 23929 25452 D CP4-6 prophage (modular protein); COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein 23929..25452 Escherichia coli O104:H4 str. 2009EL-2050 13696141 YP_006772821.1 CDS O3M_26337 NC_018654.1 26793 26927 R hypothetical protein complement(26793..26927) Escherichia coli O104:H4 str. 2009EL-2050 13696142 YP_006772822.1 CDS O3M_26342 NC_018654.1 26926 27906 D COG3039 Transposase and inactivated derivatives, IS5 family; transposase 26926..27906 Escherichia coli O104:H4 str. 2009EL-2050 13696143 YP_006772823.1 CDS O3M_26352 NC_018654.1 28499 28699 D hypothetical protein 28499..28699 Escherichia coli O104:H4 str. 2009EL-2050 13696144 YP_006772824.1 CDS O3M_26377 NC_018654.1 31987 32223 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(31987..32223) Escherichia coli O104:H4 str. 2009EL-2050 13696146 YP_006772825.1 CDS O3M_26387 NC_018654.1 32994 34124 D COG0577 ABC-type antimicrobial peptide transport system, permease component; AatP permease 32994..34124 Escherichia coli O104:H4 str. 2009EL-2050 13696147 YP_006772826.1 CDS O3M_26392 NC_018654.1 34121 35359 D outer membrane protein AatA 34121..35359 Escherichia coli O104:H4 str. 2009EL-2050 13696148 YP_006772827.1 CDS O3M_26397 NC_018654.1 35439 36077 D AatB protein 35439..36077 Escherichia coli O104:H4 str. 2009EL-2050 13696149 YP_006772828.1 CDS O3M_26402 NC_018654.1 36070 36699 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein AatC 36070..36699 Escherichia coli O104:H4 str. 2009EL-2050 13696063 YP_006772829.1 CDS O3M_26407 NC_018654.1 36779 37927 D COG0815 Apolipoprotein N-acyltransferase; AatD 36779..37927 Escherichia coli O104:H4 str. 2009EL-2050 13696064 YP_006772830.1 CDS O3M_26412 NC_018654.1 38902 40035 D COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 38902..40035 Escherichia coli O104:H4 str. 2009EL-2050 13696065 YP_006772831.1 CDS O3M_26417 NC_018654.1 40145 41713 R COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF1, IS66 family protein complement(40145..41713) Escherichia coli O104:H4 str. 2009EL-2050 13696066 YP_006772832.1 CDS O3M_26422 NC_018654.1 41755 42093 R COG3436 Transposase and inactivated derivatives; IS66 transposase complement(41755..42093) Escherichia coli O104:H4 str. 2009EL-2050 13696067 YP_006772833.1 CDS O3M_26427 NC_018654.1 42090 42524 R COG2963 Transposase and inactivated derivatives; hypothetical protein complement(42090..42524) Escherichia coli O104:H4 str. 2009EL-2050 13696068 YP_006772834.1 CDS O3M_26432 NC_018654.1 42638 42823 D COG3436 Transposase and inactivated derivatives; hypothetical protein 42638..42823 Escherichia coli O104:H4 str. 2009EL-2050 13696069 YP_006772835.1 CDS O3M_26437 NC_018654.1 43118 47212 R COG3468 Type V secretory pathway, adhesin AidA; protease IgA1 complement(43118..47212) Escherichia coli O104:H4 str. 2009EL-2050 13696070 YP_006772836.1 CDS O3M_26442 NC_018654.1 47734 47991 R COG1961 Site-specific recombinases, DNA invertase Pin homologs; recombinase complement(47734..47991) Escherichia coli O104:H4 str. 2009EL-2050 13696071 YP_006772837.1 CDS O3M_26447 NC_018654.1 48786 49586 D YubP 48786..49586 Escherichia coli O104:H4 str. 2009EL-2050 13696072 YP_006772838.1 CDS O3M_26452 NC_018654.1 49904 50413 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic transglycosylase complement(49904..50413) Escherichia coli O104:H4 str. 2009EL-2050 13696073 YP_006772839.1 CDS O3M_26457 NC_018654.1 50837 51220 D COG1082 Sugar phosphate isomerases/epimerases; conjugal transfer protein TraM 50837..51220 Escherichia coli O104:H4 str. 2009EL-2050 13696074 YP_006772840.1 CDS O3M_26462 NC_018654.1 51878 52144 R COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase complement(51878..52144) Escherichia coli O104:H4 str. 2009EL-2050 13696075 YP_006772841.1 CDS O3M_26467 NC_018654.1 52289 52564 R COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA complement(52289..52564) Escherichia coli O104:H4 str. 2009EL-2050 13696076 YP_006772842.1 CDS O3M_26472 NC_018654.1 52686 53360 D COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; conjugal transfer nickase/helicase TraI 52686..53360 Escherichia coli O104:H4 str. 2009EL-2050 13696077 YP_006772843.1 CDS O3M_26477 NC_018654.1 53365 57078 D COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; conjugal transfer nickase/helicase TraI 53365..57078 Escherichia coli O104:H4 str. 2009EL-2050 13696078 YP_006772844.1 CDS O3M_26482 NC_018654.1 57154 57291 D conjugal transfer nickase/helicase TraI 57154..57291 Escherichia coli O104:H4 str. 2009EL-2050 13696079 YP_006772845.1 CDS O3M_26487 NC_018654.1 57311 58057 D conjugal transfer pilus acetylation protein TraX 57311..58057 Escherichia coli O104:H4 str. 2009EL-2050 13696080 YP_006772846.1 CDS O3M_26492 NC_018654.1 58112 58672 D conjugal transfer fertility inhibition protein FinO 58112..58672 Escherichia coli O104:H4 str. 2009EL-2050 13696081 YP_006772847.1 CDS O3M_26497 NC_018654.1 58901 59335 D COG2963 Transposase and inactivated derivatives; hypothetical protein 58901..59335 Escherichia coli O104:H4 str. 2009EL-2050 13696082 YP_006772848.1 CDS O3M_26502 NC_018654.1 59332 59628 D COG3436 Transposase and inactivated derivatives; hypothetical protein 59332..59628 Escherichia coli O104:H4 str. 2009EL-2050 13696083 YP_006772849.1 CDS O3M_26507 NC_018654.1 59702 59887 D COG3436 Transposase and inactivated derivatives; transposase 59702..59887 Escherichia coli O104:H4 str. 2009EL-2050 13696084 YP_006772850.1 CDS O3M_26512 NC_018654.1 59941 61512 R COG3436 Transposase and inactivated derivatives; hypothetical protein complement(59941..61512) Escherichia coli O104:H4 str. 2009EL-2050 13696085 YP_006772851.1 CDS O3M_26517 NC_018654.1 61532 61879 R COG3436 Transposase and inactivated derivatives; IS66 family element, orf2 complement(61532..61879) Escherichia coli O104:H4 str. 2009EL-2050 13696086 YP_006772852.1 CDS O3M_26522 NC_018654.1 61879 62556 R COG4584 Transposase and inactivated derivatives; IS66 family transposase orfA complement(61879..62556) Escherichia coli O104:H4 str. 2009EL-2050 13696087 YP_006772853.1 CDS O3M_26527 NC_018654.1 62706 62876 D hypothetical protein 62706..62876 Escherichia coli O104:H4 str. 2009EL-2050 13696088 YP_006772854.1 CDS O3M_26532 NC_018654.1 63284 64264 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase complement(63284..64264) Escherichia coli O104:H4 str. 2009EL-2050 13696089 YP_006772855.1 CDS O3M_26537 NC_018654.1 64545 64799 D replication protein 64545..64799 Escherichia coli O104:H4 str. 2009EL-2050 13696090 YP_006772856.1 CDS O3M_26542 NC_018654.1 65037 65111 D leader peptide RepL 65037..65111 Escherichia coli O104:H4 str. 2009EL-2050 13696091 YP_006772857.1 CDS O3M_26547 NC_018654.1 65104 65292 D replication protein 65104..65292 Escherichia coli O104:H4 str. 2009EL-2050 13696092 YP_006772858.1 CDS O3M_26552 NC_018654.1 65261 65932 D replication protein 65261..65932 Escherichia coli O104:H4 str. 2009EL-2050 13696093 YP_006772859.1 CDS O3M_26557 NC_018654.1 66840 67124 D hypothetical protein 66840..67124 Escherichia coli O104:H4 str. 2009EL-2050 13696094 YP_006772860.1 CDS O3M_26562 NC_018654.1 67124 67399 D COG3668 Plasmid stabilization system protein; hypothetical protein 67124..67399 Escherichia coli O104:H4 str. 2009EL-2050 13696095 YP_006772861.1 CDS O3M_26567 NC_018654.1 67405 67650 D COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain; hypothetical protein 67405..67650 Escherichia coli O104:H4 str. 2009EL-2050 13696096 YP_006772862.1 CDS O3M_26572 NC_018654.1 67852 68013 D COG3668 Plasmid stabilization system protein; hypothetical protein 67852..68013 Escherichia coli O104:H4 str. 2009EL-2050 13696097 YP_006772863.1 CDS O3M_26577 NC_018654.1 68382 69122 D COG0582 Integrase; resolvase (protein D) 68382..69122 Escherichia coli O104:H4 str. 2009EL-2050 13696098 YP_006772864.1 CDS O3M_26582 NC_018654.1 69401 70378 R RepFIB replication protein A complement(69401..70378) Escherichia coli O104:H4 str. 2009EL-2050 13696099 YP_006772865.1 CDS O3M_26587 NC_018654.1 71464 71619 D COG3436 Transposase and inactivated derivatives; hypothetical protein 71464..71619 Escherichia coli O104:H4 str. 2009EL-2050 13696100 YP_006772866.1 CDS O3M_26592 NC_018654.1 71702 72130 R COG1487 Predicted nucleic acid-binding protein, contains PIN domain; hypothetical protein complement(71702..72130) Escherichia coli O104:H4 str. 2009EL-2050 13696101 YP_006772867.1 CDS O3M_26597 NC_018654.1 72127 72357 R COG4456 Virulence-associated protein and related proteins; hypothetical protein complement(72127..72357) Escherichia coli O104:H4 str. 2009EL-2050 13696102 YP_006772868.1 CDS O3M_26602 NC_018654.1 72952 73170 D COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid; plasmid maintenance protein CcdA 72952..73170 Escherichia coli O104:H4 str. 2009EL-2050 13696103 YP_006772869.1 CDS O3M_26607 NC_018654.1 73172 73477 D plasmid maintenance protein CcdB 73172..73477 Escherichia coli O104:H4 str. 2009EL-2050 13696104 O3M_t25262 tRNA O3M_t25262 NC_018650.1 95960 96054 R tRNA-Sec complement(95960..96054) Escherichia coli O104:H4 str. 2009EL-2050 13690026 O3M_t25264 tRNA O3M_t25264 NC_018650.1 231543 231619 D tRNA-Pro 231543..231619 Escherichia coli O104:H4 str. 2009EL-2050 13690794 O3M_t25266 tRNA O3M_t25266 NC_018650.1 531018 531094 D tRNA-Ile 531018..531094 Escherichia coli O104:H4 str. 2009EL-2050 13691085 O3M_t25268 tRNA O3M_t25268 NC_018650.1 531137 531212 D tRNA-Ala 531137..531212 Escherichia coli O104:H4 str. 2009EL-2050 13691086 O3M_t25270 tRNA O3M_t25270 NC_018650.1 534527 534602 D tRNA-Thr 534527..534602 Escherichia coli O104:H4 str. 2009EL-2050 13691089 O3M_t25272 tRNA O3M_t25272 NC_018650.1 628261 628347 D tRNA-Leu 628261..628347 Escherichia coli O104:H4 str. 2009EL-2050 13691183 O3M_t25274 tRNA O3M_t25274 NC_018650.1 632128 632204 D tRNA-Met 632128..632204 Escherichia coli O104:H4 str. 2009EL-2050 13691186 O3M_t25276 tRNA O3M_t25276 NC_018650.1 743268 743343 R tRNA-Met complement(743268..743343) Escherichia coli O104:H4 str. 2009EL-2050 13691292 O3M_t25278 tRNA O3M_t25278 NC_018650.1 947761 947836 R tRNA-Phe complement(947761..947836) Escherichia coli O104:H4 str. 2009EL-2050 13691490 O3M_t25280 tRNA O3M_t25280 NC_018650.1 1063201 1063274 D tRNA-Gly 1063201..1063274 Escherichia coli O104:H4 str. 2009EL-2050 13691759 O3M_t25282 tRNA O3M_t25282 NC_018650.1 1121578 1121654 R tRNA-Met complement(1121578..1121654) Escherichia coli O104:H4 str. 2009EL-2050 13691813 O3M_t25284 tRNA O3M_t25284 NC_018650.1 1257168 1257260 D tRNA-Ser 1257168..1257260 Escherichia coli O104:H4 str. 2009EL-2050 13692107 O3M_t25286 tRNA O3M_t25286 NC_018650.1 1257264 1257340 D tRNA-Arg 1257264..1257340 Escherichia coli O104:H4 str. 2009EL-2050 13692108 O3M_t25288 tRNA O3M_t25288 NC_018650.1 1257538 1257614 D tRNA-Arg 1257538..1257614 Escherichia coli O104:H4 str. 2009EL-2050 13692109 O3M_t25290 tRNA O3M_t25290 NC_018650.1 1257814 1257890 D tRNA-Arg 1257814..1257890 Escherichia coli O104:H4 str. 2009EL-2050 13692110 O3M_t25292 tRNA O3M_t25292 NC_018650.1 1258087 1258163 D tRNA-Arg 1258087..1258163 Escherichia coli O104:H4 str. 2009EL-2050 13692111 O3M_t25294 tRNA O3M_t25294 NC_018650.1 1290190 1290265 D tRNA-Met 1290190..1290265 Escherichia coli O104:H4 str. 2009EL-2050 13692145 O3M_t25296 tRNA O3M_t25296 NC_018650.1 1333951 1334026 D tRNA-Glu 1333951..1334026 Escherichia coli O104:H4 str. 2009EL-2050 13692263 O3M_t25298 tRNA O3M_t25298 NC_018650.1 1534287 1534362 R tRNA-Lys complement(1534287..1534362) Escherichia coli O104:H4 str. 2009EL-2050 13692614 O3M_t25300 tRNA O3M_t25300 NC_018650.1 1534367 1534442 R tRNA-Val complement(1534367..1534442) Escherichia coli O104:H4 str. 2009EL-2050 13692615 O3M_t25302 tRNA O3M_t25302 NC_018650.1 1534489 1534564 R tRNA-Val complement(1534489..1534564) Escherichia coli O104:H4 str. 2009EL-2050 13692616 O3M_t25304 tRNA O3M_t25304 NC_018650.1 1534609 1534684 R tRNA-Val complement(1534609..1534684) Escherichia coli O104:H4 str. 2009EL-2050 13692617 O3M_t25306 tRNA O3M_t25306 NC_018650.1 1537384 1537459 D tRNA-Ala 1537384..1537459 Escherichia coli O104:H4 str. 2009EL-2050 13692621 O3M_t25308 tRNA O3M_t25308 NC_018650.1 1537499 1537574 D tRNA-Ala 1537499..1537574 Escherichia coli O104:H4 str. 2009EL-2050 13692622 O3M_t25310 tRNA O3M_t25310 NC_018650.1 1591901 1591975 R tRNA-Arg complement(1591901..1591975) Escherichia coli O104:H4 str. 2009EL-2050 13693090 O3M_t25312 tRNA O3M_t25312 NC_018650.1 1756761 1756837 R tRNA-Pro complement(1756761..1756837) Escherichia coli O104:H4 str. 2009EL-2050 13693237 O3M_t25314 tRNA O3M_t25314 NC_018650.1 1997837 1997912 R tRNA-Asn complement(1997837..1997912) Escherichia coli O104:H4 str. 2009EL-2050 13693460 O3M_t25316 tRNA O3M_t25316 NC_018650.1 2000246 2000321 R tRNA-Asn complement(2000246..2000321) Escherichia coli O104:H4 str. 2009EL-2050 13693463 O3M_t25318 tRNA O3M_t25318 NC_018650.1 2002070 2002145 D tRNA-Asn 2002070..2002145 Escherichia coli O104:H4 str. 2009EL-2050 13693465 O3M_t25320 tRNA O3M_t25320 NC_018650.1 2041961 2042036 R tRNA-Asn complement(2041961..2042036) Escherichia coli O104:H4 str. 2009EL-2050 13693484 O3M_t25322 tRNA O3M_t25322 NC_018650.1 2043028 2043117 D tRNA-Ser 2043028..2043117 Escherichia coli O104:H4 str. 2009EL-2050 13693486 O3M_t25324 tRNA O3M_t25324 NC_018650.1 2096795 2096870 D tRNA-Gly 2096795..2096870 Escherichia coli O104:H4 str. 2009EL-2050 13693551 O3M_t25326 tRNA O3M_t25326 NC_018650.1 2096925 2096998 D tRNA-Cys 2096925..2096998 Escherichia coli O104:H4 str. 2009EL-2050 13693552 O3M_t25328 tRNA O3M_t25328 NC_018650.1 2097011 2097097 D tRNA-Leu 2097011..2097097 Escherichia coli O104:H4 str. 2009EL-2050 13693553 O3M_t25330 tRNA O3M_t25330 NC_018650.1 2156961 2157036 D tRNA-Met 2156961..2157036 Escherichia coli O104:H4 str. 2009EL-2050 13693622 O3M_t25332 tRNA O3M_t25332 NC_018650.1 2157044 2157120 D tRNA-Arg 2157044..2157120 Escherichia coli O104:H4 str. 2009EL-2050 13693623 O3M_t25334 tRNA O3M_t25334 NC_018650.1 2157134 2157210 D tRNA-Arg 2157134..2157210 Escherichia coli O104:H4 str. 2009EL-2050 13693624 O3M_t25336 tRNA O3M_t25336 NC_018650.1 2432033 2432109 R tRNA-Val complement(2432033..2432109) Escherichia coli O104:H4 str. 2009EL-2050 13688832 O3M_t25338 tRNA O3M_t25338 NC_018650.1 2432114 2432190 R tRNA-Val complement(2432114..2432190) Escherichia coli O104:H4 str. 2009EL-2050 13688833 O3M_t25340 tRNA O3M_t25340 NC_018650.1 2917099 2917175 R tRNA-Arg complement(2917099..2917175) Escherichia coli O104:H4 str. 2009EL-2050 13689303 O3M_t25342 tRNA O3M_t25342 NC_018650.1 2917189 2917265 R tRNA-Arg complement(2917189..2917265) Escherichia coli O104:H4 str. 2009EL-2050 13689304 O3M_t25344 tRNA O3M_t25344 NC_018650.1 2917273 2917348 R tRNA-Met complement(2917273..2917348) Escherichia coli O104:H4 str. 2009EL-2050 13689305 O3M_t25346 tRNA O3M_t25346 NC_018650.1 2957372 2957456 D tRNA-Tyr 2957372..2957456 Escherichia coli O104:H4 str. 2009EL-2050 13689350 O3M_t25348 tRNA O3M_t25348 NC_018650.1 2957491 2957575 D tRNA-Tyr 2957491..2957575 Escherichia coli O104:H4 str. 2009EL-2050 13689351 O3M_t25350 tRNA O3M_t25350 NC_018650.1 3131196 3131283 D tRNA-Ser 3131196..3131283 Escherichia coli O104:H4 str. 2009EL-2050 13689527 O3M_t25352 tRNA O3M_t25352 NC_018650.1 3170755 3170825 D tRNA-OTHER 3170755..3170825 Escherichia coli O104:H4 str. 2009EL-2050 13689570 O3M_t25354 tRNA O3M_t25354 NC_018650.1 3285541 3285617 R tRNA-Arg complement(3285541..3285617) Escherichia coli O104:H4 str. 2009EL-2050 13689673 O3M_t25356 tRNA O3M_t25356 NC_018650.1 3285631 3285707 R tRNA-Arg complement(3285631..3285707) Escherichia coli O104:H4 str. 2009EL-2050 13689674 O3M_t25358 tRNA O3M_t25358 NC_018650.1 3285717 3285792 R tRNA-Met complement(3285717..3285792) Escherichia coli O104:H4 str. 2009EL-2050 13689675 O3M_t25360 tRNA O3M_t25360 NC_018650.1 3344117 3344204 D tRNA-Ser 3344117..3344204 Escherichia coli O104:H4 str. 2009EL-2050 13689746 O3M_t25362 tRNA O3M_t25362 NC_018650.1 3451375 3451462 D tRNA-Ser 3451375..3451462 Escherichia coli O104:H4 str. 2009EL-2050 13689836 O3M_t25364 tRNA O3M_t25364 NC_018650.1 3642077 3642152 R tRNA-Lys complement(3642077..3642152) Escherichia coli O104:H4 str. 2009EL-2050 13690262 O3M_t25366 tRNA O3M_t25366 NC_018650.1 3642186 3642261 R tRNA-Lys complement(3642186..3642261) Escherichia coli O104:H4 str. 2009EL-2050 13690263 O3M_t25368 tRNA O3M_t25368 NC_018650.1 3642408 3642483 R tRNA-Lys complement(3642408..3642483) Escherichia coli O104:H4 str. 2009EL-2050 13690264 O3M_t25370 tRNA O3M_t25370 NC_018650.1 3642487 3642562 R tRNA-Val complement(3642487..3642562) Escherichia coli O104:H4 str. 2009EL-2050 13690265 O3M_t25372 tRNA O3M_t25372 NC_018650.1 3642712 3642787 R tRNA-Lys complement(3642712..3642787) Escherichia coli O104:H4 str. 2009EL-2050 13690266 O3M_t25374 tRNA O3M_t25374 NC_018650.1 3642790 3642865 R tRNA-Val complement(3642790..3642865) Escherichia coli O104:H4 str. 2009EL-2050 13690267 O3M_t25376 tRNA O3M_t25376 NC_018650.1 3642901 3642976 R tRNA-Lys complement(3642901..3642976) Escherichia coli O104:H4 str. 2009EL-2050 13690268 O3M_t25378 tRNA O3M_t25378 NC_018650.1 3720284 3720360 D tRNA-Met 3720284..3720360 Escherichia coli O104:H4 str. 2009EL-2050 13690339 O3M_t25380 tRNA O3M_t25380 NC_018650.1 3720369 3720453 D tRNA-Leu 3720369..3720453 Escherichia coli O104:H4 str. 2009EL-2050 13690340 O3M_t25382 tRNA O3M_t25382 NC_018650.1 3720477 3720551 D tRNA-Gln 3720477..3720551 Escherichia coli O104:H4 str. 2009EL-2050 13690341 O3M_t25384 tRNA O3M_t25384 NC_018650.1 3720586 3720660 D tRNA-Gln 3720586..3720660 Escherichia coli O104:H4 str. 2009EL-2050 13690342 O3M_t25386 tRNA O3M_t25386 NC_018650.1 3720676 3720752 D tRNA-Met 3720676..3720752 Escherichia coli O104:H4 str. 2009EL-2050 13690343 O3M_t25388 tRNA O3M_t25388 NC_018650.1 3720801 3720875 D tRNA-Gln 3720801..3720875 Escherichia coli O104:H4 str. 2009EL-2050 13690344 O3M_t25390 tRNA O3M_t25390 NC_018650.1 3720913 3720987 D tRNA-Gln 3720913..3720987 Escherichia coli O104:H4 str. 2009EL-2050 13690345 O3M_t25392 tRNA O3M_t25392 NC_018650.1 3842417 3842493 R tRNA-Arg complement(3842417..3842493) Escherichia coli O104:H4 str. 2009EL-2050 13690452 O3M_t25394 tRNA O3M_t25394 NC_018650.1 4060010 4060090 R tRNA-OTHER complement(4060010..4060090) Escherichia coli O104:H4 str. 2009EL-2050 13690656 O3M_t25396 tRNA O3M_t25396 NC_018650.1 4134628 4134703 R tRNA-Thr complement(4134628..4134703) Escherichia coli O104:H4 str. 2009EL-2050 13690722 O3M_t25398 tRNA O3M_t25398 NC_018650.1 4190393 4190469 R tRNA-Asp complement(4190393..4190469) Escherichia coli O104:H4 str. 2009EL-2050 13690773 O3M_t25400 tRNA O3M_t25400 NC_018650.1 4198616 4198692 R tRNA-Asp complement(4198616..4198692) Escherichia coli O104:H4 str. 2009EL-2050 13690783 O3M_t25402 tRNA O3M_t25402 NC_018650.1 4202185 4202260 R tRNA-Ala complement(4202185..4202260) Escherichia coli O104:H4 str. 2009EL-2050 13691515 O3M_t25404 tRNA O3M_t25404 NC_018650.1 4202303 4202379 R tRNA-Ile complement(4202303..4202379) Escherichia coli O104:H4 str. 2009EL-2050 13691516 O3M_t25406 tRNA O3M_t25406 NC_018650.1 4462174 4462260 D tRNA-Leu 4462174..4462260 Escherichia coli O104:H4 str. 2009EL-2050 13691909 O3M_t25408 tRNA O3M_t25408 NC_018650.1 4462289 4462375 D tRNA-Leu 4462289..4462375 Escherichia coli O104:H4 str. 2009EL-2050 13691910 O3M_t25410 tRNA O3M_t25410 NC_018650.1 4462410 4462496 D tRNA-Leu 4462410..4462496 Escherichia coli O104:H4 str. 2009EL-2050 13691911 O3M_t25412 tRNA O3M_t25412 NC_018650.1 4577706 4577790 R tRNA-Leu complement(4577706..4577790) Escherichia coli O104:H4 str. 2009EL-2050 13692174 O3M_t25414 tRNA O3M_t25414 NC_018650.1 4684527 4684602 R tRNA-Gly complement(4684527..4684602) Escherichia coli O104:H4 str. 2009EL-2050 13692363 O3M_t25416 tRNA O3M_t25416 NC_018650.1 4684638 4684713 R tRNA-Gly complement(4684638..4684713) Escherichia coli O104:H4 str. 2009EL-2050 13692364 O3M_t25418 tRNA O3M_t25418 NC_018650.1 4684750 4684825 R tRNA-Gly complement(4684750..4684825) Escherichia coli O104:H4 str. 2009EL-2050 13692365 O3M_t25420 tRNA O3M_t25420 NC_018650.1 4714553 4714628 D tRNA-Phe 4714553..4714628 Escherichia coli O104:H4 str. 2009EL-2050 13692477 O3M_t25422 tRNA O3M_t25422 NC_018650.1 4912232 4912307 R tRNA-Glu complement(4912232..4912307) Escherichia coli O104:H4 str. 2009EL-2050 13692728 O3M_t25424 tRNA O3M_t25424 NC_018650.1 4946235 4946310 R tRNA-Thr complement(4946235..4946310) Escherichia coli O104:H4 str. 2009EL-2050 13692758 O3M_t25426 tRNA O3M_t25426 NC_018650.1 4946317 4946391 R tRNA-Gly complement(4946317..4946391) Escherichia coli O104:H4 str. 2009EL-2050 13692759 O3M_t25428 tRNA O3M_t25428 NC_018650.1 4946508 4946592 R tRNA-Tyr complement(4946508..4946592) Escherichia coli O104:H4 str. 2009EL-2050 13692760 O3M_t25430 tRNA O3M_t25430 NC_018650.1 4946601 4946676 R tRNA-Thr complement(4946601..4946676) Escherichia coli O104:H4 str. 2009EL-2050 13692761 O3M_t25432 tRNA O3M_t25432 NC_018650.1 4953617 4953692 R tRNA-Glu complement(4953617..4953692) Escherichia coli O104:H4 str. 2009EL-2050 13692767 O3M_t25434 tRNA O3M_t25434 NC_018650.1 5090811 5090886 R tRNA-Ala complement(5090811..5090886) Escherichia coli O104:H4 str. 2009EL-2050 13692895 O3M_t25436 tRNA O3M_t25436 NC_018650.1 5090929 5091005 R tRNA-Ile complement(5090929..5091005) Escherichia coli O104:H4 str. 2009EL-2050 13692896 O3M_t25438 tRNA O3M_t25438 NC_018650.1 5148956 5149032 R tRNA-Pro complement(5148956..5149032) Escherichia coli O104:H4 str. 2009EL-2050 13692952 O3M_t25440 tRNA O3M_t25440 NC_018650.1 5149075 5149161 R tRNA-Leu complement(5149075..5149161) Escherichia coli O104:H4 str. 2009EL-2050 13692953 O3M_t25442 tRNA O3M_t25442 NC_018650.1 5149182 5149257 R tRNA-His complement(5149182..5149257) Escherichia coli O104:H4 str. 2009EL-2050 13692954 O3M_t25444 tRNA O3M_t25444 NC_018650.1 5149316 5149392 R tRNA-Arg complement(5149316..5149392) Escherichia coli O104:H4 str. 2009EL-2050 13692955 O3M_t25446 tRNA O3M_t25446 NC_018650.1 5184736 5184811 R tRNA-Trp complement(5184736..5184811) Escherichia coli O104:H4 str. 2009EL-2050 13692988 O3M_t25448 tRNA O3M_t25448 NC_018650.1 5184820 5184896 R tRNA-Asp complement(5184820..5184896) Escherichia coli O104:H4 str. 2009EL-2050 13692989 O3M_t25450 tRNA O3M_t25450 NC_018650.1 5188258 5188333 R tRNA-Glu complement(5188258..5188333) Escherichia coli O104:H4 str. 2009EL-2050 13692992 O3M_t26131 tRNA O3M_t26131 NC_018651.1 82766 82852 R tRNA-OTHER complement(82766..82852) Escherichia coli O104:H4 str. 2009EL-2050 13693733 O3M_t26133 tRNA O3M_t26133 NC_018651.1 83343 83418 R tRNA-Thr complement(83343..83418) Escherichia coli O104:H4 str. 2009EL-2050 13693734 O3M_t26135 tRNA O3M_t26135 NC_018651.1 83423 83509 R tRNA-Tyr complement(83423..83509) Escherichia coli O104:H4 str. 2009EL-2050 13693735 O3M_t26137 tRNA O3M_t26137 NC_018651.1 83515 83589 R tRNA-Asn complement(83515..83589) Escherichia coli O104:H4 str. 2009EL-2050 13693736 O3M_r25468 rRNA O3M_r25468 NC_018650.1 529408 530961 D 16S ribosomal RNA 529408..530961 Escherichia coli O104:H4 str. 2009EL-2050 13691084 O3M_r25482 rRNA O3M_r25482 NC_018650.1 531396 534303 D 23S ribosomal RNA 531396..534303 Escherichia coli O104:H4 str. 2009EL-2050 13691087 O3M_r25452 rRNA O3M_r25452 NC_018650.1 534397 534512 D 5S ribosomal RNA 534397..534512 Escherichia coli O104:H4 str. 2009EL-2050 13691088 O3M_r25454 rRNA O3M_r25454 NC_018650.1 534642 534757 D 5S ribosomal RNA 534642..534757 Escherichia coli O104:H4 str. 2009EL-2050 13691090 O3M_r25470 rRNA O3M_r25470 NC_018650.1 1332238 1333791 D 16S ribosomal RNA 1332238..1333791 Escherichia coli O104:H4 str. 2009EL-2050 13692262 O3M_r25484 rRNA O3M_r25484 NC_018650.1 1334220 1337127 D 23S ribosomal RNA 1334220..1337127 Escherichia coli O104:H4 str. 2009EL-2050 13692264 O3M_r25456 rRNA O3M_r25456 NC_018650.1 1337221 1337336 D 5S ribosomal RNA 1337221..1337336 Escherichia coli O104:H4 str. 2009EL-2050 13692265 O3M_r25458 rRNA O3M_r25458 NC_018650.1 4198886 4199001 R 5S ribosomal RNA complement(4198886..4199001) Escherichia coli O104:H4 str. 2009EL-2050 13690784 O3M_r25486 rRNA O3M_r25486 NC_018650.1 4199095 4202001 R 23S ribosomal RNA complement(4199095..4202001) Escherichia coli O104:H4 str. 2009EL-2050 13691514 O3M_r25472 rRNA O3M_r25472 NC_018650.1 4202436 4203989 R 16S ribosomal RNA complement(4202436..4203989) Escherichia coli O104:H4 str. 2009EL-2050 13691517 O3M_r25460 rRNA O3M_r25460 NC_018650.1 4908920 4909035 R 5S ribosomal RNA complement(4908920..4909035) Escherichia coli O104:H4 str. 2009EL-2050 13692726 O3M_r25488 rRNA O3M_r25488 NC_018650.1 4909128 4912038 R 23S ribosomal RNA complement(4909128..4912038) Escherichia coli O104:H4 str. 2009EL-2050 13692727 O3M_r25474 rRNA O3M_r25474 NC_018650.1 4912381 4913938 R 16S ribosomal RNA complement(4912381..4913938) Escherichia coli O104:H4 str. 2009EL-2050 13692729 O3M_r25462 rRNA O3M_r25462 NC_018650.1 4950310 4950425 R 5S ribosomal RNA complement(4950310..4950425) Escherichia coli O104:H4 str. 2009EL-2050 13692765 O3M_r25490 rRNA O3M_r25490 NC_018650.1 4950518 4953423 R 23S ribosomal RNA complement(4950518..4953423) Escherichia coli O104:H4 str. 2009EL-2050 13692766 O3M_r25476 rRNA O3M_r25476 NC_018650.1 4953852 4955405 R 16S ribosomal RNA complement(4953852..4955405) Escherichia coli O104:H4 str. 2009EL-2050 13692768 O3M_r25464 rRNA O3M_r25464 NC_018650.1 5087513 5087628 R 5S ribosomal RNA complement(5087513..5087628) Escherichia coli O104:H4 str. 2009EL-2050 13692893 O3M_r25492 rRNA O3M_r25492 NC_018650.1 5087722 5090627 R 23S ribosomal RNA complement(5087722..5090627) Escherichia coli O104:H4 str. 2009EL-2050 13692894 O3M_r25478 rRNA O3M_r25478 NC_018650.1 5091062 5092615 R 16S ribosomal RNA complement(5091062..5092615) Escherichia coli O104:H4 str. 2009EL-2050 13692897 O3M_r25466 rRNA O3M_r25466 NC_018650.1 5184951 5185066 R 5S ribosomal RNA complement(5184951..5185066) Escherichia coli O104:H4 str. 2009EL-2050 13692990 O3M_r25494 rRNA O3M_r25494 NC_018650.1 5185159 5188064 R 23S ribosomal RNA complement(5185159..5188064) Escherichia coli O104:H4 str. 2009EL-2050 13692991 O3M_r25480 rRNA O3M_r25480 NC_018650.1 5188407 5189960 R 16S ribosomal RNA complement(5188407..5189960) Escherichia coli O104:H4 str. 2009EL-2050 13692993