-- dump date 20140619_085257 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_006767686.1 410480140 13692995 33..1436 1 NC_018650.1 COG0593 ATPase involved in DNA replication initiation; chromosomal replication initiation protein 1436 dnaA 13692995 dnaA Escherichia coli O104:H4 str. 2009EL-2050 chromosomal replication initiation protein YP_006767686.1 33 D 1134782 CDS YP_006767687.1 410480141 13689911 1441..2541 1 NC_018650.1 COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase III subunit beta 2541 13689911 O3M_00010 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit beta YP_006767687.1 1441 D 1134782 CDS YP_006767688.1 410480142 13689912 2541..3614 1 NC_018650.1 COG1195 Recombinational DNA repair ATPase (RecF pathway); recombination protein F 3614 recF 13689912 recF Escherichia coli O104:H4 str. 2009EL-2050 recombination protein F YP_006767688.1 2541 D 1134782 CDS YP_006767689.1 410480143 13689913 3643..6057 1 NC_018650.1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA gyrase subunit B 6057 gyrB 13689913 gyrB Escherichia coli O104:H4 str. 2009EL-2050 DNA gyrase subunit B YP_006767689.1 3643 D 1134782 CDS YP_006767690.1 410480144 13689914 6077..6277 1 NC_018650.1 hypothetical protein 6277 13689914 O3M_00025 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767690.1 6077 D 1134782 CDS YP_006767691.1 410480145 13689915 6297..6695 1 NC_018650.1 COG3753 Uncharacterized protein conserved in bacteria; hypothetical protein 6695 13689915 O3M_00030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767691.1 6297 D 1134782 CDS YP_006767692.1 410480146 13689916 6810..7622 1 NC_018650.1 COG0561 Predicted hydrolases of the HAD superfamily; sugar phosphate phosphatase 7622 13689916 O3M_00035 Escherichia coli O104:H4 str. 2009EL-2050 sugar phosphate phosphatase YP_006767692.1 6810 D 1134782 CDS YP_006767693.1 410480147 13689917 complement(7668..8324) 1 NC_018650.1 hypothetical protein 8324 13689917 O3M_00040 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767693.1 7668 R 1134782 CDS YP_006767694.1 410480148 13689918 8602..9291 1 NC_018650.1 COG2186 Transcriptional regulators; DNA-binding transcriptional regulator 9291 13689918 O3M_00045 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006767694.1 8602 D 1134782 CDS YP_006767695.1 410480149 13689919 9288..10166 1 NC_018650.1 COG3734 2-keto-3-deoxy-galactonokinase; 2-oxo-3-deoxygalactonate kinase 10166 13689919 O3M_00050 Escherichia coli O104:H4 str. 2009EL-2050 2-oxo-3-deoxygalactonate kinase YP_006767695.1 9288 D 1134782 CDS YP_006767696.1 410480150 13689920 10150..10767 1 NC_018650.1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 10767 13689920 O3M_00055 Escherichia coli O104:H4 str. 2009EL-2050 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_006767696.1 10150 D 1134782 CDS YP_006767697.1 410480151 13689921 10764..11912 1 NC_018650.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; galactonate dehydratase 11912 13689921 O3M_00060 Escherichia coli O104:H4 str. 2009EL-2050 galactonate dehydratase YP_006767697.1 10764 D 1134782 CDS YP_006767698.1 410480152 13689922 12032..13324 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; D-galactonate transporter 13324 13689922 O3M_00065 Escherichia coli O104:H4 str. 2009EL-2050 D-galactonate transporter YP_006767698.1 12032 D 1134782 CDS YP_006767699.1 410480153 13689923 complement(13321..14385) 1 NC_018650.1 COG0644 Dehydrogenases (flavoproteins); oxidoreductase 14385 13689923 O3M_00070 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006767699.1 13321 R 1134782 CDS YP_006767700.1 410480154 13689924 14486..15700 1 NC_018650.1 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; hypothetical protein 15700 13689924 O3M_00075 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767700.1 14486 D 1134782 CDS YP_006767701.1 410480155 13689925 complement(15702..16034) 1 NC_018650.1 COG5645 Predicted periplasmic lipoprotein; hypothetical protein 16034 13689925 O3M_00080 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767701.1 15702 R 1134782 CDS YP_006767702.1 410480156 13689926 16340..16753 1 NC_018650.1 COG0071 Molecular chaperone (small heat shock protein); heat shock protein IbpA 16753 13689926 O3M_00085 Escherichia coli O104:H4 str. 2009EL-2050 heat shock protein IbpA YP_006767702.1 16340 D 1134782 CDS YP_006767703.1 410480157 13689927 16865..17293 1 NC_018650.1 COG0071 Molecular chaperone (small heat shock protein); heat shock chaperone IbpB 17293 13689927 O3M_00090 Escherichia coli O104:H4 str. 2009EL-2050 heat shock chaperone IbpB YP_006767703.1 16865 D 1134782 CDS YP_006767704.1 410480158 13689928 17490..19151 1 NC_018650.1 COG2985 Predicted permease; transporter 19151 13689928 O3M_00095 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006767704.1 17490 D 1134782 CDS YP_006767705.1 410480159 13689929 complement(19148..19864) 1 NC_018650.1 COG2188 Transcriptional regulators; DNA-binding transcriptional regulator 19864 13689929 O3M_00100 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006767705.1 19148 R 1134782 CDS YP_006767706.1 410480160 13689930 20160..21776 1 NC_018650.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system arbutin-like transporter subunit IIC 21776 13689930 O3M_00105 Escherichia coli O104:H4 str. 2009EL-2050 PTS system arbutin-like transporter subunit IIC YP_006767706.1 20160 D 1134782 CDS YP_006767707.1 410480161 13689931 21776..22414 1 NC_018650.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; 6-phospho-beta-glucosidase 22414 13689931 O3M_00110 Escherichia coli O104:H4 str. 2009EL-2050 6-phospho-beta-glucosidase YP_006767707.1 21776 D 1134782 CDS YP_006767708.1 410480162 13689932 22414..22590 1 NC_018650.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; glycoside hydrolase 22590 13689932 O3M_00115 Escherichia coli O104:H4 str. 2009EL-2050 glycoside hydrolase YP_006767708.1 22414 D 1134782 CDS YP_006767709.1 410480163 13689933 complement(22587..23147) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 23147 13689933 O3M_00120 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006767709.1 22587 R 1134782 CDS YP_006767710.1 410480164 13689934 23216..23491 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 23491 13689934 O3M_00125 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006767710.1 23216 D 1134782 CDS YP_006767711.1 410480165 13689935 23410..23913 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 23913 13689935 O3M_00130 Escherichia coli O104:H4 str. 2009EL-2050 transposase InsB IS1 YP_006767711.1 23410 D 1134782 CDS YP_006767712.1 410480166 13689936 complement(23928..24257) 1 NC_018650.1 DNA-binding transcriptional regulator 24257 13689936 O3M_00135 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006767712.1 23928 R 1134782 CDS YP_006767713.1 410480167 13689937 24424..26139 1 NC_018650.1 COG4146 Predicted symporter; transporter 26139 13689937 O3M_00140 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006767713.1 24424 D 1134782 CDS YP_006767714.1 410480168 13689938 26136..27629 1 NC_018650.1 COG3119 Arylsulfatase A and related enzymes; sulfatase/phosphatase 27629 13689938 O3M_00145 Escherichia coli O104:H4 str. 2009EL-2050 sulfatase/phosphatase YP_006767714.1 26136 D 1134782 CDS YP_006767715.1 410480169 13689939 complement(27676..28125) 1 NC_018650.1 inner membrane protein 28125 13689939 O3M_00150 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006767715.1 27676 R 1134782 CDS YP_006767716.1 410480170 13689940 28234..28581 1 NC_018650.1 COG2149 Predicted membrane protein; inner membrane protein YidH 28581 13689940 O3M_00155 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YidH YP_006767716.1 28234 D 1134782 CDS YP_006767717.1 410480171 13689941 28571..28933 1 NC_018650.1 hypothetical protein 28933 13689941 O3M_00160 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767717.1 28571 D 1134782 CDS YP_006767718.1 410480172 13689942 28930..29427 1 NC_018650.1 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); transcriptional regulator 29427 13689942 O3M_00165 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006767718.1 28930 D 1134782 CDS YP_006767719.1 410480173 13689943 complement(29435..30619) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein D 30619 emrD 13689943 emrD Escherichia coli O104:H4 str. 2009EL-2050 multidrug resistance protein D YP_006767719.1 29435 R 1134782 CDS YP_006767720.1 410480174 13689944 complement(31038..31127) 1 NC_018650.1 toxic peptide TisB 31127 13689944 O3M_00175 Escherichia coli O104:H4 str. 2009EL-2050 toxic peptide TisB YP_006767720.1 31038 R 1134782 CDS YP_006767721.1 410480175 13689945 complement(31415..31897) 1 NC_018650.1 hypothetical protein 31897 13689945 O3M_00180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767721.1 31415 R 1134782 CDS YP_006767722.1 410480176 13689946 31896..33584 1 NC_018650.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase catalytic subunit 33584 13689946 O3M_00185 Escherichia coli O104:H4 str. 2009EL-2050 acetolactate synthase catalytic subunit YP_006767722.1 31896 D 1134782 CDS YP_006767723.1 410480177 13689947 33588..33878 1 NC_018650.1 COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase 1 regulatory subunit 33878 13689947 O3M_00190 Escherichia coli O104:H4 str. 2009EL-2050 acetolactate synthase 1 regulatory subunit YP_006767723.1 33588 D 1134782 CDS YP_006767724.1 410480178 13689948 33953..34543 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator UhpA 34543 13689948 O3M_00195 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator UhpA YP_006767724.1 33953 D 1134782 CDS YP_006767725.1 410480179 13689949 34543..36045 1 NC_018650.1 COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific; sensory histidine kinase UhpB 36045 13689949 O3M_00200 Escherichia coli O104:H4 str. 2009EL-2050 sensory histidine kinase UhpB YP_006767725.1 34543 D 1134782 CDS YP_006767726.1 410480180 13689950 36055..37374 1 NC_018650.1 COG2271 Sugar phosphate permease; regulatory protein UhpC 37374 13689950 O3M_00205 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein UhpC YP_006767726.1 36055 D 1134782 CDS YP_006767727.1 410480181 13689951 37512..38903 1 NC_018650.1 COG2271 Sugar phosphate permease; sugar phosphate antiporter 38903 uhpT 13689951 uhpT Escherichia coli O104:H4 str. 2009EL-2050 sugar phosphate antiporter YP_006767727.1 37512 D 1134782 CDS YP_006767728.1 410480182 13689952 complement(38948..40714) 1 NC_018650.1 COG1001 Adenine deaminase; cryptic adenine deaminase 40714 13689952 O3M_00215 Escherichia coli O104:H4 str. 2009EL-2050 cryptic adenine deaminase YP_006767728.1 38948 R 1134782 CDS YP_006767729.1 410480183 13689953 40889..42223 1 NC_018650.1 COG2252 Permeases; hypothetical protein 42223 13689953 O3M_00220 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767729.1 40889 D 1134782 CDS YP_006767730.1 410480184 13689954 42276..42728 1 NC_018650.1 COG0442 Prolyl-tRNA synthetase; hypothetical protein 42728 13689954 O3M_00225 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767730.1 42276 D 1134782 CDS YP_006767731.1 410480185 13689955 42939..44123 1 NC_018650.1 COG2814 Arabinose efflux permease; ribonucleoside transporter 44123 nepI 13689955 nepI Escherichia coli O104:H4 str. 2009EL-2050 ribonucleoside transporter YP_006767731.1 42939 D 1134782 CDS YP_006767732.1 410480186 13689956 complement(44164..44457) 1 NC_018650.1 hypothetical protein 44457 13689956 O3M_00235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767732.1 44164 R 1134782 CDS YP_006767733.1 410480187 13689957 complement(44462..44581) 1 NC_018650.1 hypothetical protein 44581 13689957 O3M_00240 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767733.1 44462 R 1134782 CDS YP_006767734.1 410480188 13689958 44679..45497 1 NC_018650.1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; hypothetical protein 45497 13689958 O3M_00245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767734.1 44679 D 1134782 CDS YP_006767735.1 410480189 13689959 complement(45501..46424) 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 46424 13689959 O3M_00250 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767735.1 45501 R 1134782 CDS YP_006767736.1 410480190 13689960 complement(46535..47719) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; sugar efflux system 47719 13689960 O3M_00255 Escherichia coli O104:H4 str. 2009EL-2050 sugar efflux system YP_006767736.1 46535 R 1134782 CDS YP_006767737.1 410480191 13689961 complement(48101..48250) 1 NC_018650.1 COG3943 Virulence protein; hypothetical protein 48250 13689961 O3M_00260 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767737.1 48101 R 1134782 CDS YP_006767738.1 410480192 13689962 complement(48512..49357) 1 NC_018650.1 hypothetical protein 49357 13689962 O3M_00265 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767738.1 48512 R 1134782 CDS YP_006767739.1 410480193 13689963 complement(49442..49639) 1 NC_018650.1 hypothetical protein 49639 13689963 O3M_00270 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767739.1 49442 R 1134782 CDS YP_006767740.1 410480194 13689964 complement(49659..50147) 1 NC_018650.1 hypothetical protein 50147 13689964 O3M_00275 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767740.1 49659 R 1134782 CDS YP_006767741.1 410480195 13689965 complement(50144..50521) 1 NC_018650.1 hypothetical protein 50521 13689965 O3M_00280 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767741.1 50144 R 1134782 CDS YP_006767742.1 410480196 13689966 complement(50568..50945) 1 NC_018650.1 hypothetical protein 50945 13689966 O3M_00285 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767742.1 50568 R 1134782 CDS YP_006767743.1 410480197 13689967 complement(50995..51108) 1 NC_018650.1 hypothetical protein 51108 13689967 O3M_00290 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767743.1 50995 R 1134782 CDS YP_006767744.1 410480198 13689968 complement(51108..51329) 1 NC_018650.1 hypothetical protein 51329 13689968 O3M_00295 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767744.1 51108 R 1134782 CDS YP_006767745.1 410480199 13689969 complement(51392..51868) 1 NC_018650.1 COG2003 DNA repair proteins; DNA repair protein 51868 13689969 O3M_00300 Escherichia coli O104:H4 str. 2009EL-2050 DNA repair protein YP_006767745.1 51392 R 1134782 CDS YP_006767746.1 410480200 13689970 complement(51884..52357) 1 NC_018650.1 hypothetical protein 52357 13689970 O3M_00305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767746.1 51884 R 1134782 CDS YP_006767747.1 410480201 13689971 complement(52523..52696) 1 NC_018650.1 antirestriction protein 52696 13689971 O3M_00310 Escherichia coli O104:H4 str. 2009EL-2050 antirestriction protein YP_006767747.1 52523 R 1134782 CDS YP_006767748.1 410480202 13689972 complement(52696..53514) 1 NC_018650.1 hypothetical protein 53514 13689972 O3M_00315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767748.1 52696 R 1134782 CDS YP_006767749.1 410480203 13689973 complement(53669..53827) 1 NC_018650.1 hypothetical protein 53827 13689973 O3M_00320 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767749.1 53669 R 1134782 CDS YP_006767750.1 410480204 13689974 complement(53898..56744) 1 NC_018650.1 COG5295 Autotransporter adhesin; antigen 43 precursor (AG43, Fluffing protein) 56744 13689974 O3M_00325 Escherichia coli O104:H4 str. 2009EL-2050 antigen 43 precursor (AG43, Fluffing protein) YP_006767750.1 53898 R 1134782 CDS YP_006767751.1 410480205 13689975 complement(57117..57989) 1 NC_018650.1 COG3596 Predicted GTPase; hypothetical protein 57989 13689975 O3M_00330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767751.1 57117 R 1134782 CDS YP_006767752.1 410480206 13689976 complement(58088..58960) 1 NC_018650.1 hypothetical protein 58960 13689976 O3M_00335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767752.1 58088 R 1134782 CDS YP_006767753.1 410480207 13689977 complement(60603..60815) 1 NC_018650.1 COG1484 DNA replication protein; IstB ATP binding domain-containing protein 60815 13689977 O3M_00340 Escherichia coli O104:H4 str. 2009EL-2050 IstB ATP binding domain-containing protein YP_006767753.1 60603 R 1134782 CDS YP_006767754.1 410480208 13689978 61448..61645 1 NC_018650.1 hypothetical protein 61645 13689978 O3M_00345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767754.1 61448 D 1134782 CDS YP_006767755.1 410480209 13689979 complement(61548..62156) 1 NC_018650.1 hypothetical protein 62156 13689979 O3M_00350 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767755.1 61548 R 1134782 CDS YP_006767756.1 410480210 13689980 complement(62245..62451) 1 NC_018650.1 COG3311 Predicted transcriptional regulator; Prophage CP4-57 regulatory protein 62451 13689980 O3M_00355 Escherichia coli O104:H4 str. 2009EL-2050 Prophage CP4-57 regulatory protein YP_006767756.1 62245 R 1134782 CDS YP_006767757.1 410480211 13689981 63230..63370 1 NC_018650.1 hemolysin expression modulating protein 63370 13689981 O3M_00360 Escherichia coli O104:H4 str. 2009EL-2050 hemolysin expression modulating protein YP_006767757.1 63230 D 1134782 CDS YP_006767758.1 410480212 13689982 64114..64683 1 NC_018650.1 hypothetical protein 64683 13689982 O3M_00365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767758.1 64114 D 1134782 CDS YP_006767759.1 410480213 13689983 64849..65232 1 NC_018650.1 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 65232 13689983 O3M_00370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767759.1 64849 D 1134782 CDS YP_006767760.1 410480214 13689984 65229..65438 1 NC_018650.1 hypothetical protein 65438 13689984 O3M_00375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767760.1 65229 D 1134782 CDS YP_006767761.1 410480215 13689985 65985..66686 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; transposase 66686 13689985 O3M_00380 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006767761.1 65985 D 1134782 CDS YP_006767762.1 410480216 13689986 66671..67531 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; transporter permease 67531 13689986 O3M_00385 Escherichia coli O104:H4 str. 2009EL-2050 transporter permease YP_006767762.1 66671 D 1134782 CDS YP_006767763.1 410480217 13689987 complement(67563..68837) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; tetracycline efflux protein 68837 13689987 O3M_00390 Escherichia coli O104:H4 str. 2009EL-2050 tetracycline efflux protein YP_006767763.1 67563 R 1134782 CDS YP_006767764.1 410480218 13689988 68841..69518 1 NC_018650.1 COG1309 Transcriptional regulator; tetracycline repressor protein 69518 13689988 O3M_00395 Escherichia coli O104:H4 str. 2009EL-2050 tetracycline repressor protein YP_006767764.1 68841 D 1134782 CDS YP_006767765.1 410480219 13689989 complement(69550..69792) 1 NC_018650.1 transposase 69792 13689989 O3M_00400 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006767765.1 69550 R 1134782 CDS YP_006767766.1 410480220 13689990 69715..69879 1 NC_018650.1 hypothetical protein 69879 13689990 O3M_00405 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767766.1 69715 D 1134782 CDS YP_006767767.1 410480221 13689991 70088..70204 1 NC_018650.1 hypothetical protein 70204 13689991 O3M_00410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767767.1 70088 D 1134782 CDS YP_006767768.1 410480222 13689992 complement(70426..70758) 1 NC_018650.1 hypothetical protein 70758 13689992 O3M_00415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767768.1 70426 R 1134782 CDS YP_006767769.1 410480223 13689993 complement(70795..71229) 1 NC_018650.1 COG0789 Predicted transcriptional regulators; transcriptional regulator MerR 71229 13689993 O3M_00420 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator MerR YP_006767769.1 70795 R 1134782 CDS YP_006767770.1 410480224 13689994 71301..71651 1 NC_018650.1 mercuric transport protein 71651 13689994 O3M_00425 Escherichia coli O104:H4 str. 2009EL-2050 mercuric transport protein YP_006767770.1 71301 D 1134782 CDS YP_006767771.1 410480225 13689995 71665..71940 1 NC_018650.1 COG2608 Copper chaperone; mercury resistance operon protein MerP 71940 13689995 O3M_00430 Escherichia coli O104:H4 str. 2009EL-2050 mercury resistance operon protein MerP YP_006767771.1 71665 D 1134782 CDS YP_006767772.1 410480226 13689996 71976..72398 1 NC_018650.1 mercury transport protein MerC 72398 13689996 O3M_00435 Escherichia coli O104:H4 str. 2009EL-2050 mercury transport protein MerC YP_006767772.1 71976 D 1134782 CDS YP_006767773.1 410480227 13689997 72450..74144 1 NC_018650.1 COG2608 Copper chaperone; mercuric reductase 74144 13689997 O3M_00440 Escherichia coli O104:H4 str. 2009EL-2050 mercuric reductase YP_006767773.1 72450 D 1134782 CDS YP_006767774.1 410480228 13689998 74162..74524 1 NC_018650.1 COG0789 Predicted transcriptional regulators; transcriptional regulator MerD 74524 13689998 O3M_00445 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator MerD YP_006767774.1 74162 D 1134782 CDS YP_006767775.1 410480229 13689999 74521..74757 1 NC_018650.1 mercury resistance protein 74757 13689999 O3M_00450 Escherichia coli O104:H4 str. 2009EL-2050 mercury resistance protein YP_006767775.1 74521 D 1134782 CDS YP_006767776.1 410480230 13690000 74754..75461 1 NC_018650.1 COG2200 FOG: EAL domain; hypothetical protein 75461 13690000 O3M_00455 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767776.1 74754 D 1134782 CDS YP_006767777.1 410480231 13690001 75500..76798 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; TniA protein 76798 13690001 O3M_00460 Escherichia coli O104:H4 str. 2009EL-2050 TniA protein YP_006767777.1 75500 D 1134782 CDS YP_006767778.1 410480232 13690002 76845..77549 1 NC_018650.1 COG3316 Transposase and inactivated derivatives; transposase 77549 13690002 O3M_00465 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006767778.1 76845 D 1134782 CDS YP_006767779.1 410480233 13690003 complement(77610..78446) 1 NC_018650.1 COG3570 Streptomycin 6-kinase; streptomycin phosphotransferase 78446 13690003 O3M_00470 Escherichia coli O104:H4 str. 2009EL-2050 streptomycin phosphotransferase YP_006767779.1 77610 R 1134782 CDS YP_006767780.1 410480234 13690004 complement(78446..79249) 1 NC_018650.1 COG3231 Aminoglycoside phosphotransferase; hypothetical protein 79249 13690004 O3M_00475 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767780.1 78446 R 1134782 CDS YP_006767781.1 410480235 13690005 complement(79310..80125) 1 NC_018650.1 COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase 80125 13690005 O3M_00480 Escherichia coli O104:H4 str. 2009EL-2050 dihydropteroate synthase YP_006767781.1 79310 R 1134782 CDS YP_006767782.1 410480236 13690006 complement(80433..81284) 1 NC_018650.1 replication protein C 81284 13690006 O3M_00485 Escherichia coli O104:H4 str. 2009EL-2050 replication protein C YP_006767782.1 80433 R 1134782 CDS YP_006767783.1 410480237 13690007 complement(81271..81978) 1 NC_018650.1 COG3598 RecA-family ATPase; replication protein A 81978 13690007 O3M_00490 Escherichia coli O104:H4 str. 2009EL-2050 replication protein A YP_006767783.1 81271 R 1134782 CDS YP_006767784.1 410480238 13690008 complement(82040..82744) 1 NC_018650.1 COG3316 Transposase and inactivated derivatives; transposase 82744 13690008 O3M_00495 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006767784.1 82040 R 1134782 CDS YP_006767785.1 410480239 13690009 complement(82791..83192) 1 NC_018650.1 COG1110 Reverse gyrase; hypothetical protein 83192 13690009 O3M_00500 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767785.1 82791 R 1134782 CDS YP_006767786.1 410480240 13690010 complement(83342..84202) 1 NC_018650.1 COG2367 Beta-lactamase class A; beta-lactamase TEM 84202 13690010 O3M_00505 Escherichia coli O104:H4 str. 2009EL-2050 beta-lactamase TEM YP_006767786.1 83342 R 1134782 CDS YP_006767787.1 410480241 13690011 complement(84385..84627) 1 NC_018650.1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; hypothetical protein 84627 13690011 O3M_00510 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767787.1 84385 R 1134782 CDS YP_006767788.1 410480242 13690012 84702..85406 1 NC_018650.1 COG3316 Transposase and inactivated derivatives; transposase 85406 13690012 O3M_00515 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006767788.1 84702 D 1134782 CDS YP_006767789.1 410480243 13690013 complement(85603..85803) 1 NC_018650.1 modulator protein 85803 13690013 O3M_00520 Escherichia coli O104:H4 str. 2009EL-2050 modulator protein YP_006767789.1 85603 R 1134782 CDS YP_006767790.1 410480244 13690014 86018..86197 1 NC_018650.1 transcriptional regulator 86197 13690014 O3M_00525 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006767790.1 86018 D 1134782 CDS YP_006767791.1 410480245 13690015 complement(86156..87169) 1 NC_018650.1 COG0582 Integrase; integrase/recombinase 87169 13690015 O3M_00530 Escherichia coli O104:H4 str. 2009EL-2050 integrase/recombinase YP_006767791.1 86156 R 1134782 CDS YP_006767792.1 410480246 13690016 87327..87800 1 NC_018650.1 COG0262 Dihydrofolate reductase; dihydrofolate reductase 87800 13690016 O3M_00535 Escherichia coli O104:H4 str. 2009EL-2050 dihydrofolate reductase YP_006767792.1 87327 D 1134782 CDS YP_006767793.1 410480247 13690017 88030..88377 1 NC_018650.1 COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein 88377 13690017 O3M_00540 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux protein YP_006767793.1 88030 D 1134782 CDS YP_006767794.1 410480248 13690018 88371..89150 1 NC_018650.1 COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase 89150 13690018 O3M_00545 Escherichia coli O104:H4 str. 2009EL-2050 dihydropteroate synthase YP_006767794.1 88371 D 1134782 CDS YP_006767795.1 410480249 13690019 complement(89184..89888) 1 NC_018650.1 COG3316 Transposase and inactivated derivatives; transposase 89888 13690019 O3M_00550 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006767795.1 89184 R 1134782 CDS YP_006767796.1 410480250 13690020 89947..90501 1 NC_018650.1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; Tn21 resolvase 90501 13690020 O3M_00555 Escherichia coli O104:H4 str. 2009EL-2050 Tn21 resolvase YP_006767796.1 89947 D 1134782 CDS YP_006767797.1 410480251 13690021 90504..93470 1 NC_018650.1 COG4644 Transposase and inactivated derivatives, TnpA family; transposase TnpA, Tn21 93470 13690021 O3M_00560 Escherichia coli O104:H4 str. 2009EL-2050 transposase TnpA, Tn21 YP_006767797.1 90504 D 1134782 CDS YP_006767798.1 410480252 13690022 93537..93626 1 NC_018650.1 acetyltransferase 93626 13690022 O3M_00565 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006767798.1 93537 D 1134782 CDS YP_006767799.1 410480253 13690023 93660..93935 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 93935 13690023 O3M_00570 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006767799.1 93660 D 1134782 CDS YP_006767800.1 410480254 13690024 93854..94357 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 94357 13690024 O3M_00575 Escherichia coli O104:H4 str. 2009EL-2050 transposase InsB IS1 YP_006767800.1 93854 D 1134782 CDS YP_006767801.1 410480255 13690025 complement(94476..95660) 1 NC_018650.1 COG0582 Integrase; hypothetical protein 95660 13690025 O3M_00580 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767801.1 94476 R 1134782 CDS YP_006767802.1 410480256 13690027 96347..97729 1 NC_018650.1 COG2211 Na+/melibiose symporter and related transporters; transporter 97729 13690027 O3M_00585 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006767802.1 96347 D 1134782 CDS YP_006767803.1 410480257 13690028 97739..100057 1 NC_018650.1 COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; alpha-glucosidase 100057 13690028 O3M_00590 Escherichia coli O104:H4 str. 2009EL-2050 alpha-glucosidase YP_006767803.1 97739 D 1134782 CDS YP_006767804.1 410480258 13690029 complement(100110..101819) 1 NC_018650.1 hypothetical protein 101819 13690029 O3M_00595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767804.1 100110 R 1134782 CDS YP_006767805.1 410480259 13690030 complement(101940..103331) 1 NC_018650.1 COG2233 Xanthine/uracil permeases; purine permease yicE 103331 13690030 O3M_00600 Escherichia coli O104:H4 str. 2009EL-2050 purine permease yicE YP_006767805.1 101940 R 1134782 CDS YP_006767806.1 410480260 13690031 103611..104816 1 NC_018650.1 COG0786 Na+/glutamate symporter; sodium/glutamate symporter 104816 13690031 O3M_00605 Escherichia coli O104:H4 str. 2009EL-2050 sodium/glutamate symporter YP_006767806.1 103611 D 1134782 CDS YP_006767807.1 410480261 13690032 complement(104982..107063) 1 NC_018650.1 COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG 107063 13690032 O3M_00610 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent DNA helicase RecG YP_006767807.1 104982 R 1134782 CDS YP_006767808.1 410480262 13690033 complement(107069..107758) 1 NC_018650.1 COG0566 rRNA methylases; tRNA guanosine-2'-O-methyltransferase 107758 13690033 O3M_00615 Escherichia coli O104:H4 str. 2009EL-2050 tRNA guanosine-2'-O-methyltransferase YP_006767808.1 107069 R 1134782 CDS YP_006767809.1 410480263 13690034 complement(107765..109873) 1 NC_018650.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 109873 13690034 O3M_00620 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_006767809.1 107765 R 1134782 CDS YP_006767810.1 410480264 13690035 complement(109892..110167) 1 NC_018650.1 COG1758 DNA-directed RNA polymerase, subunit K/omega; DNA-directed RNA polymerase subunit omega 110167 rpoZ 13690035 rpoZ Escherichia coli O104:H4 str. 2009EL-2050 DNA-directed RNA polymerase subunit omega YP_006767810.1 109892 R 1134782 CDS YP_006767811.1 410480265 13690036 complement(110222..110845) 1 NC_018650.1 COG0194 Guanylate kinase; guanylate kinase 110845 gmk 13690036 gmk Escherichia coli O104:H4 str. 2009EL-2050 guanylate kinase YP_006767811.1 110222 R 1134782 CDS YP_006767812.1 410480266 13690037 111103..112785 1 NC_018650.1 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase LigB 112785 ligB 13690037 ligB Escherichia coli O104:H4 str. 2009EL-2050 NAD-dependent DNA ligase LigB YP_006767812.1 111103 D 1134782 CDS YP_006767813.1 410480267 13690038 complement(112782..113399) 1 NC_018650.1 COG2860 Predicted membrane protein; hypothetical protein 113399 13690038 O3M_00640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767813.1 112782 R 1134782 CDS YP_006767814.1 410480268 13690039 complement(113691..114515) 1 NC_018650.1 DNA-damage-inducible protein D 114515 dinD 13690039 dinD Escherichia coli O104:H4 str. 2009EL-2050 DNA-damage-inducible protein D YP_006767814.1 113691 R 1134782 CDS YP_006767815.1 410480269 13690040 complement(114736..115599) 1 NC_018650.1 COG1561 Uncharacterized stress-induced protein; hypothetical protein 115599 13690040 O3M_00650 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767815.1 114736 R 1134782 CDS YP_006767816.1 410480270 13690041 115726..116442 1 NC_018650.1 COG0689 RNase PH; ribonuclease PH 116442 rph 13690041 rph Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease PH YP_006767816.1 115726 D 1134782 CDS YP_006767817.1 410480271 13690042 116508..117149 1 NC_018650.1 COG0461 Orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 117149 pyrE 13690042 pyrE Escherichia coli O104:H4 str. 2009EL-2050 orotate phosphoribosyltransferase YP_006767817.1 116508 D 1134782 CDS YP_006767818.1 410480272 13690043 complement(117186..117782) 1 NC_018650.1 COG1309 Transcriptional regulator; division inhibitor protein 117782 slmA 13690043 slmA Escherichia coli O104:H4 str. 2009EL-2050 division inhibitor protein YP_006767818.1 117186 R 1134782 CDS YP_006767819.1 410480273 13690044 complement(117889..118344) 1 NC_018650.1 COG0756 dUTPase; deoxyuridine 5'-triphosphate nucleotidohydrolase 118344 dut 13690044 dut Escherichia coli O104:H4 str. 2009EL-2050 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_006767819.1 117889 R 1134782 CDS YP_006767820.1 410480274 13690045 complement(118325..119545) 1 NC_018650.1 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 119545 13690045 O3M_00675 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_006767820.1 118325 R 1134782 CDS YP_006767821.1 410480275 13690046 119717..120385 1 NC_018650.1 COG2003 DNA repair proteins; hypothetical protein 120385 13690046 O3M_00680 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767821.1 119717 D 1134782 CDS YP_006767822.1 410480276 13690047 120602..120838 1 NC_018650.1 COG0227 Ribosomal protein L28; 50S ribosomal protein L28 120838 rpmB 13690047 rpmB Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L28 YP_006767822.1 120602 D 1134782 CDS YP_006767823.1 410480277 13690048 120859..121026 1 NC_018650.1 COG0267 Ribosomal protein L33; 50S ribosomal protein L33 121026 rpmG 13690048 rpmG Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L33 YP_006767823.1 120859 D 1134782 CDS YP_006767824.1 410480278 13690049 121124..121933 1 NC_018650.1 COG0266 Formamidopyrimidine-DNA glycosylase; formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase 121933 13690049 O3M_00695 Escherichia coli O104:H4 str. 2009EL-2050 formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase YP_006767824.1 121124 D 1134782 CDS YP_006767825.1 410480279 13690050 complement(121972..122451) 1 NC_018650.1 COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase 122451 coaD 13690050 coaD Escherichia coli O104:H4 str. 2009EL-2050 phosphopantetheine adenylyltransferase YP_006767825.1 121972 R 1134782 CDS YP_006767826.1 410480280 13690051 complement(122459..123736) 1 NC_018650.1 COG1519 3-deoxy-D-manno-octulosonic-acid transferase; 3-deoxy-D-manno-octulosonic-acid transferase 123736 13690051 O3M_00705 Escherichia coli O104:H4 str. 2009EL-2050 3-deoxy-D-manno-octulosonic-acid transferase YP_006767826.1 122459 R 1134782 CDS YP_006767827.1 410480281 13690052 124149..125207 1 NC_018650.1 COG0859 ADP-heptose:LPS heptosyltransferase; lipopolysaccharide core biosynthesis protein 125207 13690052 O3M_00710 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide core biosynthesis protein YP_006767827.1 124149 D 1134782 CDS YP_006767828.1 410480282 13690053 125204..126328 1 NC_018650.1 COG0438 Glycosyltransferase; glucosyltransferase I RfaG 126328 13690053 O3M_00715 Escherichia coli O104:H4 str. 2009EL-2050 glucosyltransferase I RfaG YP_006767828.1 125204 D 1134782 CDS YP_006767829.1 410480283 13690054 126321..127118 1 NC_018650.1 COG0515 Serine/threonine protein kinase; lipopolysaccharide core heptose(I) kinase RfaP 127118 13690054 O3M_00720 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide core heptose(I) kinase RfaP YP_006767829.1 126321 D 1134782 CDS YP_006767830.1 410480284 13690055 127161..128168 1 NC_018650.1 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,3-galactosyltransferase 128168 13690055 O3M_00725 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide 1,3-galactosyltransferase YP_006767830.1 127161 D 1134782 CDS YP_006767831.1 410480285 13690056 128194..128901 1 NC_018650.1 COG0515 Serine/threonine protein kinase; lipopolysaccharide core biosynthesis protein 128901 13690056 O3M_00730 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide core biosynthesis protein YP_006767831.1 128194 D 1134782 CDS YP_006767832.1 410480286 13690057 128926..129939 1 NC_018650.1 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glucosyltransferase 129939 13690057 O3M_00735 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide 1,2-glucosyltransferase YP_006767832.1 128926 D 1134782 CDS YP_006767833.1 410480287 13690058 129948..131090 1 NC_018650.1 COG0438 Glycosyltransferase; lipopolysaccharide 1,2-N-acetylglucosaminetransferase 131090 13690058 O3M_00740 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide 1,2-N-acetylglucosaminetransferase YP_006767833.1 129948 D 1134782 CDS YP_006767834.1 410480288 13690059 complement(131126..132334) 1 NC_018650.1 COG3307 Lipid A core - O-antigen ligase and related enzymes; O-antigen ligase RfaL 132334 13690059 O3M_00745 Escherichia coli O104:H4 str. 2009EL-2050 O-antigen ligase RfaL YP_006767834.1 131126 R 1134782 CDS YP_006767835.1 410480289 13690060 complement(132331..133323) 1 NC_018650.1 COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose--LPS heptosyltransferase 133323 13690060 O3M_00750 Escherichia coli O104:H4 str. 2009EL-2050 ADP-heptose--LPS heptosyltransferase YP_006767835.1 132331 R 1134782 CDS YP_006767836.1 410480290 13690061 complement(133327..134373) 1 NC_018650.1 COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose--LPS heptosyltransferase 134373 13690061 O3M_00755 Escherichia coli O104:H4 str. 2009EL-2050 ADP-heptose--LPS heptosyltransferase YP_006767836.1 133327 R 1134782 CDS YP_006767837.1 410480291 13690062 complement(134383..135315) 1 NC_018650.1 COG0451 Nucleoside-diphosphate-sugar epimerases; ADP-L-glycero-D-manno-heptose-6-epimerase 135315 rfaD 13690062 rfaD Escherichia coli O104:H4 str. 2009EL-2050 ADP-L-glycero-D-manno-heptose-6-epimerase YP_006767837.1 134383 R 1134782 CDS YP_006767838.1 410480292 13690063 135619..136476 1 NC_018650.1 hypothetical protein 136476 13690063 O3M_00765 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767838.1 135619 D 1134782 CDS YP_006767839.1 410480293 13690064 136751..137947 1 NC_018650.1 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 2-amino-3-ketobutyrate coenzyme A ligase 137947 13690064 O3M_00770 Escherichia coli O104:H4 str. 2009EL-2050 2-amino-3-ketobutyrate coenzyme A ligase YP_006767839.1 136751 D 1134782 CDS YP_006767840.1 410480294 13690065 137957..138982 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; L-threonine 3-dehydrogenase 138982 tdh 13690065 tdh Escherichia coli O104:H4 str. 2009EL-2050 L-threonine 3-dehydrogenase YP_006767840.1 137957 D 1134782 CDS YP_006767841.1 410480295 13690066 139221..140255 1 NC_018650.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 140255 13690066 O3M_00780 Escherichia coli O104:H4 str. 2009EL-2050 glycosyl transferase family protein YP_006767841.1 139221 D 1134782 CDS YP_006767842.1 410480296 13690067 complement(140242..141201) 1 NC_018650.1 COG2861 Uncharacterized protein conserved in bacteria; polysaccharide deacetylase 141201 13690067 O3M_00785 Escherichia coli O104:H4 str. 2009EL-2050 polysaccharide deacetylase YP_006767842.1 140242 R 1134782 CDS YP_006767843.1 410480297 13690068 complement(141205..142488) 1 NC_018650.1 COG4942 Membrane-bound metallopeptidase; AmiB activator 142488 13690068 O3M_00790 Escherichia coli O104:H4 str. 2009EL-2050 AmiB activator YP_006767843.1 141205 R 1134782 CDS YP_006767844.1 410480298 13690069 complement(142498..144042) 1 NC_018650.1 COG0696 Phosphoglyceromutase; phosphoglyceromutase 144042 13690069 O3M_00795 Escherichia coli O104:H4 str. 2009EL-2050 phosphoglyceromutase YP_006767844.1 142498 R 1134782 CDS YP_006767845.1 410480299 13690070 144287..144718 1 NC_018650.1 COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 144718 13690070 O3M_00800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767845.1 144287 D 1134782 CDS YP_006767846.1 410480300 13690071 144860..145111 1 NC_018650.1 COG0695 Glutaredoxin and related proteins; glutaredoxin 3 145111 13690071 O3M_00805 Escherichia coli O104:H4 str. 2009EL-2050 glutaredoxin 3 YP_006767846.1 144860 D 1134782 CDS YP_006767847.1 410480301 13690072 145174..145641 1 NC_018650.1 COG1952 Preprotein translocase subunit SecB; preprotein translocase subunit SecB 145641 13690072 O3M_00810 Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit SecB YP_006767847.1 145174 D 1134782 CDS YP_006767848.1 410480302 13690073 145641..146660 1 NC_018650.1 COG0240 Glycerol-3-phosphate dehydrogenase; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 146660 gpsA 13690073 gpsA Escherichia coli O104:H4 str. 2009EL-2050 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_006767848.1 145641 D 1134782 CDS YP_006767849.1 410480303 13690074 146740..147561 1 NC_018650.1 COG1045 Serine acetyltransferase; serine acetyltransferase 147561 cysE 13690074 cysE Escherichia coli O104:H4 str. 2009EL-2050 serine acetyltransferase YP_006767849.1 146740 D 1134782 CDS YP_006767850.1 410480304 13690075 complement(147614..148087) 1 NC_018650.1 COG0219 Predicted rRNA methylase (SpoU class); rRNA methylase 148087 13690075 O3M_00825 Escherichia coli O104:H4 str. 2009EL-2050 rRNA methylase YP_006767850.1 147614 R 1134782 CDS YP_006767851.1 410480305 13690076 complement(148273..149463) 1 NC_018650.1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase 149463 lldD 13690076 lldD Escherichia coli O104:H4 str. 2009EL-2050 L-lactate dehydrogenase YP_006767851.1 148273 R 1134782 CDS YP_006767852.1 410480306 13690077 complement(149460..150236) 1 NC_018650.1 COG2186 Transcriptional regulators; DNA-binding transcriptional repressor LldR 150236 13690077 O3M_00835 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor LldR YP_006767852.1 149460 R 1134782 CDS YP_006767853.1 410480307 13690078 complement(150236..151891) 1 NC_018650.1 COG1620 L-lactate permease; L-lactate permease 151891 13690078 O3M_00840 Escherichia coli O104:H4 str. 2009EL-2050 L-lactate permease YP_006767853.1 150236 R 1134782 CDS YP_006767854.1 410480308 13690079 complement(152260..157110) 1 NC_018650.1 COG5295 Autotransporter adhesin; adhesin 157110 13690079 O3M_00845 Escherichia coli O104:H4 str. 2009EL-2050 adhesin YP_006767854.1 152260 R 1134782 CDS YP_006767855.1 410480309 13690080 complement(157154..157837) 1 NC_018650.1 hypothetical protein 157837 13690080 O3M_00850 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767855.1 157154 R 1134782 CDS YP_006767856.1 410480310 13690081 complement(158381..158743) 1 NC_018650.1 hypothetical protein 158743 13690081 O3M_00855 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767856.1 158381 R 1134782 CDS YP_006767857.1 410480311 13690082 159028..159237 1 NC_018650.1 hypothetical protein 159237 13690082 O3M_00860 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767857.1 159028 D 1134782 CDS YP_006767858.1 410480312 13690083 complement(159249..159836) 1 NC_018650.1 COG3722 Transcriptional regulator; mannitol repressor protein 159836 mtlR 13690083 mtlR Escherichia coli O104:H4 str. 2009EL-2050 mannitol repressor protein YP_006767858.1 159249 R 1134782 CDS YP_006767859.1 410480313 13690084 complement(159836..160984) 1 NC_018650.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannitol-1-phosphate 5-dehydrogenase 160984 13690084 O3M_00870 Escherichia coli O104:H4 str. 2009EL-2050 mannitol-1-phosphate 5-dehydrogenase YP_006767859.1 159836 R 1134782 CDS YP_006767860.1 410480314 13690085 complement(161214..163127) 1 NC_018650.1 COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system mannitol-specific transporter subunit IICBA 163127 13690085 O3M_00875 Escherichia coli O104:H4 str. 2009EL-2050 PTS system mannitol-specific transporter subunit IICBA YP_006767860.1 161214 R 1134782 CDS YP_006767861.1 410480315 13690086 163664..164026 1 NC_018650.1 hypothetical protein 164026 13690086 O3M_00880 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767861.1 163664 D 1134782 CDS YP_006767862.1 410480316 13690087 164029..165165 1 NC_018650.1 COG1566 Multidrug resistance efflux pump; hypothetical protein 165165 13690087 O3M_00885 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767862.1 164029 D 1134782 CDS YP_006767863.1 410480317 13690088 complement(166764..167225) 1 NC_018650.1 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 167225 13690088 O3M_00890 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767863.1 166764 R 1134782 CDS YP_006767864.1 410480318 13690089 complement(167237..168181) 1 NC_018650.1 COG3209 Rhs family protein; Rhs family protein 168181 13690089 O3M_00895 Escherichia coli O104:H4 str. 2009EL-2050 Rhs family protein YP_006767864.1 167237 R 1134782 CDS YP_006767865.1 410480319 13690090 complement(168223..169065) 1 NC_018650.1 COG1413 FOG: HEAT repeat; lyase 169065 13690090 O3M_00900 Escherichia coli O104:H4 str. 2009EL-2050 lyase YP_006767865.1 168223 R 1134782 CDS YP_006767866.1 410480320 13690091 complement(169170..169553) 1 NC_018650.1 hypothetical protein 169553 13690091 O3M_00905 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767866.1 169170 R 1134782 CDS YP_006767867.1 410480321 13690092 complement(169795..173760) 1 NC_018650.1 COG3209 Rhs family protein; rhsB element core protein RshB 173760 13690092 O3M_00910 Escherichia coli O104:H4 str. 2009EL-2050 rhsB element core protein RshB YP_006767867.1 169795 R 1134782 CDS YP_006767868.1 410480322 13690093 173989..174597 1 NC_018650.1 COG0625 Glutathione S-transferase; glutathione S-transferase 174597 13690093 O3M_00915 Escherichia coli O104:H4 str. 2009EL-2050 glutathione S-transferase YP_006767868.1 173989 D 1134782 CDS YP_006767869.1 410480323 13690094 174695..176086 1 NC_018650.1 COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; selenocysteine synthase 176086 13690094 O3M_00920 Escherichia coli O104:H4 str. 2009EL-2050 selenocysteine synthase YP_006767869.1 174695 D 1134782 CDS YP_006767870.1 410480324 13690095 176083..177927 1 NC_018650.1 COG3276 Selenocysteine-specific translation elongation factor; selenocysteinyl-tRNA-specific translation factor 177927 13690095 O3M_00925 Escherichia coli O104:H4 str. 2009EL-2050 selenocysteinyl-tRNA-specific translation factor YP_006767870.1 176083 D 1134782 CDS YP_006767871.1 410480325 13690096 178117..179268 1 NC_018650.1 COG1454 Alcohol dehydrogenase, class IV; alcohol dehydrogenase 179268 13690096 O3M_00930 Escherichia coli O104:H4 str. 2009EL-2050 alcohol dehydrogenase YP_006767871.1 178117 D 1134782 CDS YP_006767872.1 410480326 13690097 179433..180971 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 180971 13690097 O3M_00935 Escherichia coli O104:H4 str. 2009EL-2050 aldehyde dehydrogenase YP_006767872.1 179433 D 1134782 CDS YP_006767873.1 410480327 13690098 complement(181190..181402) 1 NC_018650.1 hypothetical protein 181402 13690098 O3M_00940 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767873.1 181190 R 1134782 CDS YP_006767874.1 410480328 13690099 181516..181839 1 NC_018650.1 hypothetical protein 181839 13690099 O3M_00945 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767874.1 181516 D 1134782 CDS YP_006767875.1 410480329 13690100 181845..182981 1 NC_018650.1 COG1566 Multidrug resistance efflux pump; efflux pump membrane protein 182981 13690100 O3M_00950 Escherichia coli O104:H4 str. 2009EL-2050 efflux pump membrane protein YP_006767875.1 181845 D 1134782 CDS YP_006767876.1 410480330 13690101 complement(182978..183952) 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 183952 13690101 O3M_00955 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006767876.1 182978 R 1134782 CDS YP_006767877.1 410480331 13690102 184076..184816 1 NC_018650.1 COG3713 Outer membrane protein V; hypothetical protein 184816 13690102 O3M_00960 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767877.1 184076 D 1134782 CDS YP_006767878.1 410480332 13690103 complement(185163..185858) 1 NC_018650.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase 185858 sgbE 13690103 sgbE Escherichia coli O104:H4 str. 2009EL-2050 L-ribulose-5-phosphate 4-epimerase YP_006767878.1 185163 R 1134782 CDS YP_006767879.1 410480333 13690104 complement(185852..186712) 1 NC_018650.1 COG3623 Putative L-xylulose-5-phosphate 3-epimerase; L-xylulose 5-phosphate 3-epimerase 186712 13690104 O3M_00970 Escherichia coli O104:H4 str. 2009EL-2050 L-xylulose 5-phosphate 3-epimerase YP_006767879.1 185852 R 1134782 CDS YP_006767880.1 410480334 13690105 complement(186705..187367) 1 NC_018650.1 COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-keto-L-gulonate-6-phosphate decarboxylase 187367 sgbH 13690105 sgbH Escherichia coli O104:H4 str. 2009EL-2050 3-keto-L-gulonate-6-phosphate decarboxylase YP_006767880.1 186705 R 1134782 CDS YP_006767881.1 410480335 13690106 complement(187364..188860) 1 NC_018650.1 COG1070 Sugar (pentulose and hexulose) kinases; L-xylulose kinase 188860 13690106 O3M_00980 Escherichia coli O104:H4 str. 2009EL-2050 L-xylulose kinase YP_006767881.1 187364 R 1134782 CDS YP_006767882.1 410480336 13690107 complement(188864..189850) 1 NC_018650.1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component; transporter 189850 13690107 O3M_00985 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006767882.1 188864 R 1134782 CDS YP_006767883.1 410480337 13690108 complement(189863..191140) 1 NC_018650.1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; L-dehydroascorbate transporter large permease subunit 191140 13690108 O3M_00990 Escherichia coli O104:H4 str. 2009EL-2050 L-dehydroascorbate transporter large permease subunit YP_006767883.1 189863 R 1134782 CDS YP_006767884.1 410480338 13690109 complement(191143..191616) 1 NC_018650.1 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component; 2,3-diketo-L-gulonate TRAP transporter small permease 191616 13690109 O3M_00995 Escherichia coli O104:H4 str. 2009EL-2050 2,3-diketo-L-gulonate TRAP transporter small permease YP_006767884.1 191143 R 1134782 CDS YP_006767885.1 410480339 13690110 complement(191734..192201) 1 NC_018650.1 COG2731 Beta-galactosidase, beta subunit; hypothetical protein 192201 13690110 O3M_01000 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767885.1 191734 R 1134782 CDS YP_006767886.1 410480340 13690111 complement(192213..193211) 1 NC_018650.1 COG2055 Malate/L-lactate dehydrogenases; 2,3-diketo-L-gulonate reductase 193211 13690111 O3M_01005 Escherichia coli O104:H4 str. 2009EL-2050 2,3-diketo-L-gulonate reductase YP_006767886.1 192213 R 1134782 CDS YP_006767887.1 410480341 13690112 193412..194260 1 NC_018650.1 COG1414 Transcriptional regulator; DNA-binding transcriptional repressor 194260 13690112 O3M_01010 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor YP_006767887.1 193412 D 1134782 CDS YP_006767888.1 410480342 13690113 194362..194835 1 NC_018650.1 COG1142 Fe-S-cluster-containing hydrogenase components 2; 4Fe-4S binding protein 194835 13690113 O3M_01015 Escherichia coli O104:H4 str. 2009EL-2050 4Fe-4S binding protein YP_006767888.1 194362 D 1134782 CDS YP_006767889.1 410480343 13690114 complement(194855..194983) 1 NC_018650.1 hypothetical protein 194983 13690114 O3M_01020 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767889.1 194855 R 1134782 CDS YP_006767890.1 410480344 13690115 complement(194987..196240) 1 NC_018650.1 COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; valine--pyruvate transaminase 196240 avtA 13690115 avtA Escherichia coli O104:H4 str. 2009EL-2050 valine--pyruvate transaminase YP_006767890.1 194987 R 1134782 CDS YP_006767891.1 410480345 13690116 198767..199591 1 NC_018650.1 COG2992 Uncharacterized FlgJ-related protein; hypothetical protein 199591 13690116 O3M_01040 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767891.1 198767 D 1134782 CDS YP_006767892.1 410480346 13690117 complement(199787..200965) 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional activator, xylose-binding protein 200965 13690117 O3M_01045 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator, xylose-binding protein YP_006767892.1 199787 R 1134782 CDS YP_006767893.1 410480347 13690118 complement(201043..202224) 1 NC_018650.1 COG4214 ABC-type xylose transport system, permease component; D-xylose ABC transporter permease 202224 13690118 O3M_01050 Escherichia coli O104:H4 str. 2009EL-2050 D-xylose ABC transporter permease YP_006767893.1 201043 R 1134782 CDS YP_006767894.1 410480348 13690119 complement(202202..203743) 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; xylose transporter ATP-binding subunit 203743 13690119 O3M_01055 Escherichia coli O104:H4 str. 2009EL-2050 xylose transporter ATP-binding subunit YP_006767894.1 202202 R 1134782 CDS YP_006767895.1 410480349 13690120 complement(203821..204813) 1 NC_018650.1 COG4213 ABC-type xylose transport system, periplasmic component; D-xylose transporter subunit XylF 204813 xylF 13690120 xylF Escherichia coli O104:H4 str. 2009EL-2050 D-xylose transporter subunit XylF YP_006767895.1 203821 R 1134782 CDS YP_006767896.1 410480350 13690121 205179..206501 1 NC_018650.1 COG2115 Xylose isomerase; xylose isomerase 206501 13690121 O3M_01065 Escherichia coli O104:H4 str. 2009EL-2050 xylose isomerase YP_006767896.1 205179 D 1134782 CDS YP_006767897.1 410480351 13690122 206573..208027 1 NC_018650.1 COG1070 Sugar (pentulose and hexulose) kinases; xylulokinase 208027 13690122 O3M_01070 Escherichia coli O104:H4 str. 2009EL-2050 xylulokinase YP_006767897.1 206573 D 1134782 CDS YP_006767898.1 410480352 13690123 208196..208537 1 NC_018650.1 COG4682 Predicted membrane protein; hypothetical protein 208537 13690123 O3M_01075 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767898.1 208196 D 1134782 CDS YP_006767899.1 410480353 13690124 208583..209020 1 NC_018650.1 COG4682 Predicted membrane protein; hypothetical protein 209020 13690124 O3M_01080 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767899.1 208583 D 1134782 CDS YP_006767900.1 410480354 13690125 complement(209062..210057) 1 NC_018650.1 COG3274 Uncharacterized protein conserved in bacteria; hypothetical protein 210057 13690125 O3M_01085 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767900.1 209062 R 1134782 CDS YP_006767901.1 410480355 13690126 210232..210531 1 NC_018650.1 outer membrane lipoprotein 210531 13690126 O3M_01090 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006767901.1 210232 D 1134782 CDS YP_006767902.1 410480356 13690127 210626..211537 1 NC_018650.1 COG0752 Glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA synthetase subunit alpha 211537 glyQ 13690127 glyQ Escherichia coli O104:H4 str. 2009EL-2050 glycyl-tRNA synthetase subunit alpha YP_006767902.1 210626 D 1134782 CDS YP_006767903.1 410480357 13690128 211547..213616 1 NC_018650.1 COG0751 Glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase subunit beta 213616 glyS 13690128 glyS Escherichia coli O104:H4 str. 2009EL-2050 glycyl-tRNA synthetase subunit beta YP_006767903.1 211547 D 1134782 CDS YP_006767904.1 410480358 13690129 213882..214094 1 NC_018650.1 small toxic polypeptide 214094 13690129 O3M_01105 Escherichia coli O104:H4 str. 2009EL-2050 small toxic polypeptide YP_006767904.1 213882 D 1134782 CDS YP_006767905.1 410480359 13690130 complement(214282..214494) 1 NC_018650.1 COG1278 Cold shock proteins; RNA chaperone/anti-terminator 214494 13690130 O3M_01110 Escherichia coli O104:H4 str. 2009EL-2050 RNA chaperone/anti-terminator YP_006767905.1 214282 R 1134782 CDS YP_006767906.1 410480360 13690131 complement(214775..215065) 1 NC_018650.1 COG2944 Predicted transcriptional regulator; transcriptional regulator 215065 13690131 O3M_01115 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006767906.1 214775 R 1134782 CDS YP_006767907.1 410480361 13690132 215499..216209 1 NC_018650.1 hypothetical protein 216209 13690132 O3M_01120 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767907.1 215499 D 1134782 CDS YP_006767908.1 410480362 13690133 complement(216259..217233) 1 NC_018650.1 COG1052 Lactate dehydrogenase and related dehydrogenases; bifunctional glyoxylate/hydroxypyruvate reductase B 217233 13690133 O3M_01125 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional glyoxylate/hydroxypyruvate reductase B YP_006767908.1 216259 R 1134782 CDS YP_006767909.1 410480363 13690134 complement(217337..217996) 1 NC_018650.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; outer membrane lipoprotein 217996 13690134 O3M_01130 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006767909.1 217337 R 1134782 CDS YP_006767910.1 410480364 13690135 218149..220482 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; biotin sulfoxide reductase 220482 13690135 O3M_01135 Escherichia coli O104:H4 str. 2009EL-2050 biotin sulfoxide reductase YP_006767910.1 218149 D 1134782 CDS YP_006767911.1 410480365 13690136 complement(220451..220891) 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 220891 13690136 O3M_01140 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006767911.1 220451 R 1134782 CDS YP_006767912.1 410480366 13690785 complement(220888..221451) 1 NC_018650.1 COG2818 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase 221451 13690785 O3M_01145 Escherichia coli O104:H4 str. 2009EL-2050 3-methyladenine DNA glycosylase YP_006767912.1 220888 R 1134782 CDS YP_006767913.1 410480367 13690786 221609..222307 1 NC_018650.1 hypothetical protein 222307 13690786 O3M_01150 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767913.1 221609 D 1134782 CDS YP_006767914.1 410480368 13690787 222536..223738 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 223738 13690787 O3M_01155 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006767914.1 222536 D 1134782 CDS YP_006767915.1 410480369 13690788 224062..224586 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; long polar fimbrial protein LpfA 224586 13690788 O3M_01160 Escherichia coli O104:H4 str. 2009EL-2050 long polar fimbrial protein LpfA YP_006767915.1 224062 D 1134782 CDS YP_006767916.1 410480370 13690789 224670..225356 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; long polar fimbrial chaperone LpfB 225356 13690789 O3M_01165 Escherichia coli O104:H4 str. 2009EL-2050 long polar fimbrial chaperone LpfB YP_006767916.1 224670 D 1134782 CDS YP_006767917.1 410480371 13690790 225380..227911 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; long polar fimbrial outer membrane usher protein LpfC 227911 13690790 O3M_01170 Escherichia coli O104:H4 str. 2009EL-2050 long polar fimbrial outer membrane usher protein LpfC YP_006767917.1 225380 D 1134782 CDS YP_006767918.1 410480372 13690791 227922..228977 1 NC_018650.1 long polar fimbrial protein LpfD 228977 13690791 O3M_01175 Escherichia coli O104:H4 str. 2009EL-2050 long polar fimbrial protein LpfD YP_006767918.1 227922 D 1134782 CDS YP_006767919.1 410480373 13690792 228983..229507 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; long polar fimbrial protein LpfE 229507 13690792 O3M_01180 Escherichia coli O104:H4 str. 2009EL-2050 long polar fimbrial protein LpfE YP_006767919.1 228983 D 1134782 CDS YP_006767920.1 410480374 13690793 229760..231451 1 NC_018650.1 COG2194 Predicted membrane-associated, metal-dependent hydrolase; phosphoethanolamine transferase 231451 13690793 O3M_01185 Escherichia coli O104:H4 str. 2009EL-2050 phosphoethanolamine transferase YP_006767920.1 229760 D 1134782 CDS YP_006767921.1 410480375 13690795 232363..233970 1 NC_018650.1 COG0747 ABC-type dipeptide transport system, periplasmic component; dipeptide transport protein 233970 13690795 O3M_01190 Escherichia coli O104:H4 str. 2009EL-2050 dipeptide transport protein YP_006767921.1 232363 D 1134782 CDS YP_006767922.1 410480376 13690796 234121..235140 1 NC_018650.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide transporter permease DppB 235140 13690796 O3M_01195 Escherichia coli O104:H4 str. 2009EL-2050 dipeptide transporter permease DppB YP_006767922.1 234121 D 1134782 CDS YP_006767923.1 410480377 13690797 235150..236052 1 NC_018650.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide transporter 236052 13690797 O3M_01200 Escherichia coli O104:H4 str. 2009EL-2050 dipeptide transporter YP_006767923.1 235150 D 1134782 CDS YP_006767924.1 410480378 13690798 236063..237046 1 NC_018650.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; dipeptide transporter ATP-binding subunit 237046 dppD 13690798 dppD Escherichia coli O104:H4 str. 2009EL-2050 dipeptide transporter ATP-binding subunit YP_006767924.1 236063 D 1134782 CDS YP_006767925.1 410480379 13690799 237043..238047 1 NC_018650.1 COG4608 ABC-type oligopeptide transport system, ATPase component; dipeptide transporter ATP-binding subunit 238047 dppF 13690799 dppF Escherichia coli O104:H4 str. 2009EL-2050 dipeptide transporter ATP-binding subunit YP_006767925.1 237043 D 1134782 CDS YP_006767926.1 410480380 13690800 complement(238077..239348) 1 NC_018650.1 COG0814 Amino acid permeases; transporter 239348 13690800 O3M_01215 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006767926.1 238077 R 1134782 CDS YP_006767927.1 410480381 13690801 240306..240413 1 NC_018650.1 toxic polypeptide, small 240413 13690801 O3M_01220 Escherichia coli O104:H4 str. 2009EL-2050 toxic polypeptide, small YP_006767927.1 240306 D 1134782 CDS YP_006767928.1 410480382 13690802 240789..240896 1 NC_018650.1 toxic polypeptide, small 240896 13690802 O3M_01225 Escherichia coli O104:H4 str. 2009EL-2050 toxic polypeptide, small YP_006767928.1 240789 D 1134782 CDS YP_006767929.1 410480383 13690803 complement(240983..242662) 1 NC_018650.1 hypothetical protein 242662 13690803 O3M_01230 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767929.1 240983 R 1134782 CDS YP_006767930.1 410480384 13690804 complement(242659..242850) 1 NC_018650.1 hypothetical protein 242850 13690804 O3M_01235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767930.1 242659 R 1134782 CDS YP_006767931.1 410480385 13690805 244692..244880 1 NC_018650.1 hypothetical protein 244880 13690805 O3M_01250 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767931.1 244692 D 1134782 CDS YP_006767932.1 410480386 13690806 244892..245644 1 NC_018650.1 COG1192 ATPases involved in chromosome partitioning; cell division protein 245644 13690806 O3M_01255 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein YP_006767932.1 244892 D 1134782 CDS YP_006767933.1 410480387 13690807 245641..248259 1 NC_018650.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; cellulose synthase catalytic subunit 248259 bcsA 13690807 bcsA Escherichia coli O104:H4 str. 2009EL-2050 cellulose synthase catalytic subunit YP_006767933.1 245641 D 1134782 CDS YP_006767934.1 410480388 13690808 248270..250609 1 NC_018650.1 cellulose synthase regulator protein 250609 13690808 O3M_01265 Escherichia coli O104:H4 str. 2009EL-2050 cellulose synthase regulator protein YP_006767934.1 248270 D 1134782 CDS YP_006767935.1 410480389 13690809 250616..251722 1 NC_018650.1 COG3405 Endoglucanase Y; endo-1,4-D-glucanase 251722 13690809 O3M_01270 Escherichia coli O104:H4 str. 2009EL-2050 endo-1,4-D-glucanase YP_006767935.1 250616 D 1134782 CDS YP_006767936.1 410480390 13690810 251704..255177 1 NC_018650.1 COG0457 FOG: TPR repeat; cellulose synthase subunit BcsC 255177 13690810 O3M_01275 Escherichia coli O104:H4 str. 2009EL-2050 cellulose synthase subunit BcsC YP_006767936.1 251704 D 1134782 CDS YP_006767937.1 410480391 13690811 255292..257247 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 257247 13690811 O3M_01280 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006767937.1 255292 D 1134782 CDS YP_006767938.1 410480392 13690812 257430..258716 1 NC_018650.1 COG1301 Na+/H+-dicarboxylate symporters; C4-dicarboxylate transporter DctA 258716 13690812 O3M_01285 Escherichia coli O104:H4 str. 2009EL-2050 C4-dicarboxylate transporter DctA YP_006767938.1 257430 D 1134782 CDS YP_006767939.1 410480393 13690813 258937..260433 1 NC_018650.1 COG0612 Predicted Zn-dependent peptidases; zinc-dependent peptidase 260433 13690813 O3M_01290 Escherichia coli O104:H4 str. 2009EL-2050 zinc-dependent peptidase YP_006767939.1 258937 D 1134782 CDS YP_006767940.1 410480394 13690814 complement(260529..261458) 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; ketodeoxygluconokinase 261458 13690814 O3M_01295 Escherichia coli O104:H4 str. 2009EL-2050 ketodeoxygluconokinase YP_006767940.1 260529 R 1134782 CDS YP_006767941.1 410480395 13690815 261690..262457 1 NC_018650.1 COG2200 FOG: EAL domain; cyclic-di-GMP phosphodiesterase 262457 13690815 O3M_01300 Escherichia coli O104:H4 str. 2009EL-2050 cyclic-di-GMP phosphodiesterase YP_006767941.1 261690 D 1134782 CDS YP_006767942.1 410480396 13690816 262527..264587 1 NC_018650.1 COG2982 Uncharacterized protein involved in outer membrane biogenesis; outer membrane biogenesis protein 264587 13690816 O3M_01305 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane biogenesis protein YP_006767942.1 262527 D 1134782 CDS YP_006767943.1 410480397 13690817 complement(264821..266143) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; inner membrane metabolite transport protein yhjE 266143 13690817 O3M_01310 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane metabolite transport protein yhjE YP_006767943.1 264821 R 1134782 CDS YP_006767944.1 410480398 13690818 complement(266554..267567) 1 NC_018650.1 COG1295 Predicted membrane protein; ribonuclease 267567 13690818 O3M_01315 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease YP_006767944.1 266554 R 1134782 CDS YP_006767945.1 410480399 13690819 complement(267616..268587) 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 268587 13690819 O3M_01320 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006767945.1 267616 R 1134782 CDS YP_006767946.1 410480400 13690820 269035..269637 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; HTH-type transcriptional regulator yhjB 269637 13690820 O3M_01325 Escherichia coli O104:H4 str. 2009EL-2050 HTH-type transcriptional regulator yhjB YP_006767946.1 269035 D 1134782 CDS YP_006767947.1 410480401 13690821 complement(269688..271337) 1 NC_018650.1 COG1626 Neutral trehalase; trehalase 271337 treF 13690821 treF Escherichia coli O104:H4 str. 2009EL-2050 trehalase YP_006767947.1 269688 R 1134782 CDS YP_006767948.1 410480402 13690822 271742..273139 1 NC_018650.1 COG1858 Cytochrome c peroxidase; cytochrome C peroxidase 273139 13690822 O3M_01335 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome C peroxidase YP_006767948.1 271742 D 1134782 CDS YP_006767949.1 410480403 13690823 273350..274750 1 NC_018650.1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins; glutamate decarboxylase 274750 13690823 O3M_01340 Escherichia coli O104:H4 str. 2009EL-2050 glutamate decarboxylase YP_006767949.1 273350 D 1134782 CDS YP_006767950.1 410480404 13690824 275120..275944 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator GadX 275944 13690824 O3M_01345 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator GadX YP_006767950.1 275120 D 1134782 CDS YP_006767951.1 410480405 13690825 276312..277040 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator GadW 277040 13690825 O3M_01350 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator GadW YP_006767951.1 276312 D 1134782 CDS YP_006767952.1 410480406 13690826 complement(277403..280516) 1 NC_018650.1 COG0841 Cation/multidrug efflux pump; multidrug transporter MdtF, RpoS-dependent 280516 13690826 O3M_01355 Escherichia coli O104:H4 str. 2009EL-2050 multidrug transporter MdtF, RpoS-dependent YP_006767952.1 277403 R 1134782 CDS YP_006767953.1 410480407 13690827 complement(280541..281698) 1 NC_018650.1 COG0845 Membrane-fusion protein; multidrug efflux system protein MdtE 281698 13690827 O3M_01360 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein MdtE YP_006767953.1 280541 R 1134782 CDS YP_006767954.1 410480408 13690828 281604..281720 1 NC_018650.1 hypothetical protein 281720 13690828 O3M_01365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767954.1 281604 D 1134782 CDS YP_006767955.1 410480409 13690829 281758..282036 1 NC_018650.1 hypothetical protein 282036 13690829 O3M_01370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767955.1 281758 D 1134782 CDS YP_006767956.1 410480410 13690830 complement(282037..282564) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator 282564 13690830 O3M_01375 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator YP_006767956.1 282037 R 1134782 CDS YP_006767957.1 410480411 13690831 complement(283363..283935) 1 NC_018650.1 COG3247 Uncharacterized conserved protein; acid-resistance membrane protein 283935 13690831 O3M_01380 Escherichia coli O104:H4 str. 2009EL-2050 acid-resistance membrane protein YP_006767957.1 283363 R 1134782 CDS YP_006767958.1 410480412 13690832 284190..284522 1 NC_018650.1 acid-resistance protein 284522 13690832 O3M_01385 Escherichia coli O104:H4 str. 2009EL-2050 acid-resistance protein YP_006767958.1 284190 D 1134782 CDS YP_006767959.1 410480413 13690833 284626..284964 1 NC_018650.1 acid-resistance protein 284964 hdeB 13690833 hdeB Escherichia coli O104:H4 str. 2009EL-2050 acid-resistance protein YP_006767959.1 284626 D 1134782 CDS YP_006767960.1 410480414 13690834 285028..285675 1 NC_018650.1 COG1285 Uncharacterized membrane protein; Mg(2+) transport ATPase 285675 13690834 O3M_01395 Escherichia coli O104:H4 str. 2009EL-2050 Mg(2+) transport ATPase YP_006767960.1 285028 D 1134782 CDS YP_006767961.1 410480415 13690835 complement(285717..286247) 1 NC_018650.1 COG0055 F0F1-type ATP synthase, beta subunit; DNA-binding transcriptional regulator 286247 13690835 O3M_01400 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006767961.1 285717 R 1134782 CDS YP_006767962.1 410480416 13690836 complement(286403..286969) 1 NC_018650.1 COG3065 Starvation-inducible outer membrane lipoprotein; outer membrane lipoprotein 286969 13690836 O3M_01405 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006767962.1 286403 R 1134782 CDS YP_006767963.1 410480417 13690837 complement(287293..288438) 1 NC_018650.1 COG1518 Uncharacterized protein predicted to be involved in DNA repair; hypothetical protein 288438 13690837 O3M_01410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767963.1 287293 R 1134782 CDS YP_006767964.1 410480418 13690838 complement(289018..290031) 1 NC_018650.1 COG0701 Predicted permeases; hypothetical protein 290031 13690838 O3M_01415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767964.1 289018 R 1134782 CDS YP_006767965.1 410480419 13690839 290138..290434 1 NC_018650.1 COG0640 Predicted transcriptional regulators; hypothetical protein 290434 13690839 O3M_01420 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767965.1 290138 D 1134782 CDS YP_006767966.1 410480420 13690840 complement(290568..290993) 1 NC_018650.1 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase 290993 13690840 O3M_01425 Escherichia coli O104:H4 str. 2009EL-2050 arsenate reductase YP_006767966.1 290568 R 1134782 CDS YP_006767967.1 410480421 13690841 complement(291006..292295) 1 NC_018650.1 COG1055 Na+/H+ antiporter NhaD and related arsenite permeases; arsenical pump membrane protein 292295 13690841 O3M_01430 Escherichia coli O104:H4 str. 2009EL-2050 arsenical pump membrane protein YP_006767967.1 291006 R 1134782 CDS YP_006767968.1 410480422 13690842 complement(292349..292702) 1 NC_018650.1 COG0640 Predicted transcriptional regulators; DNA-binding transcriptional repressor ArsR 292702 13690842 O3M_01435 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor ArsR YP_006767968.1 292349 R 1134782 CDS YP_006767969.1 410480423 13690843 293376..293525 1 NC_018650.1 hypothetical protein 293525 13690843 O3M_01440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767969.1 293376 D 1134782 CDS YP_006767970.1 410480424 13690844 complement(293579..294931) 1 NC_018650.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; glutathione reductase 294931 13690844 O3M_01445 Escherichia coli O104:H4 str. 2009EL-2050 glutathione reductase YP_006767970.1 293579 R 1134782 CDS YP_006767971.1 410480425 13690845 complement(295003..295845) 1 NC_018650.1 COG2961 Protein involved in catabolism of external DNA; DNA processing protein 295845 13690845 O3M_01450 Escherichia coli O104:H4 str. 2009EL-2050 DNA processing protein YP_006767971.1 295003 R 1134782 CDS YP_006767972.1 410480426 13690846 296048..298090 1 NC_018650.1 COG0339 Zn-dependent oligopeptidases; oligopeptidase A 298090 13690846 O3M_01455 Escherichia coli O104:H4 str. 2009EL-2050 oligopeptidase A YP_006767972.1 296048 D 1134782 CDS YP_006767973.1 410480427 13690847 298098..298850 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; methyltransferase 298850 13690847 O3M_01460 Escherichia coli O104:H4 str. 2009EL-2050 methyltransferase YP_006767973.1 298098 D 1134782 CDS YP_006767974.1 410480428 13690848 complement(298899..300368) 1 NC_018650.1 COG3104 Dipeptide/tripeptide permease; dipeptide/tripeptide permease B 300368 13690848 O3M_01465 Escherichia coli O104:H4 str. 2009EL-2050 dipeptide/tripeptide permease B YP_006767974.1 298899 R 1134782 CDS YP_006767975.1 410480429 13690849 complement(300686..301120) 1 NC_018650.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress global response regulator UspA 301120 13690849 O3M_01470 Escherichia coli O104:H4 str. 2009EL-2050 universal stress global response regulator UspA YP_006767975.1 300686 R 1134782 CDS YP_006767976.1 410480430 13690850 301511..301846 1 NC_018650.1 universal stress protein UspB 301846 13690850 O3M_01475 Escherichia coli O104:H4 str. 2009EL-2050 universal stress protein UspB YP_006767976.1 301511 D 1134782 CDS YP_006767977.1 410480431 13690851 complement(301917..303416) 1 NC_018650.1 COG0306 Phosphate/sulphate permeases; Low-affinity inorganic phosphate transporter 1 303416 13690851 O3M_01480 Escherichia coli O104:H4 str. 2009EL-2050 Low-affinity inorganic phosphate transporter 1 YP_006767977.1 301917 R 1134782 CDS YP_006767978.1 410480432 13690852 303648..304850 1 NC_018650.1 COG2081 Predicted flavoproteins; oxidoreductase with FAD/NAD(P)-binding domain 304850 13690852 O3M_01485 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase with FAD/NAD(P)-binding domain YP_006767978.1 303648 D 1134782 CDS YP_006767979.1 410480433 13690853 304993..305835 1 NC_018650.1 Tn7-like transposase TnsA 305835 13690853 O3M_01490 Escherichia coli O104:H4 str. 2009EL-2050 Tn7-like transposase TnsA YP_006767979.1 304993 D 1134782 CDS YP_006767980.1 410480434 13690854 305822..307945 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; Tn7-like transposition protein TnsB 307945 13690854 O3M_01495 Escherichia coli O104:H4 str. 2009EL-2050 Tn7-like transposition protein TnsB YP_006767980.1 305822 D 1134782 CDS YP_006767981.1 410480435 13690855 307945..309393 1 NC_018650.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Tn7-like transposition protein TnsC 309393 13690855 O3M_01500 Escherichia coli O104:H4 str. 2009EL-2050 Tn7-like transposition protein TnsC YP_006767981.1 307945 D 1134782 CDS YP_006767982.1 410480436 13690856 309425..310990 1 NC_018650.1 TnsD 310990 13690856 O3M_01505 Escherichia coli O104:H4 str. 2009EL-2050 TnsD YP_006767982.1 309425 D 1134782 CDS YP_006767983.1 410480437 13690857 311002..311223 1 NC_018650.1 hypothetical protein 311223 13690857 O3M_01510 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767983.1 311002 D 1134782 CDS YP_006767984.1 410480438 13690858 complement(311227..312840) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; transposase 312840 13690858 O3M_01515 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006767984.1 311227 R 1134782 CDS YP_006767985.1 410480439 13690859 complement(312871..313221) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 313221 13690859 O3M_01520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767985.1 312871 R 1134782 CDS YP_006767986.1 410480440 13690860 complement(313218..313652) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 313652 13690860 O3M_01525 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767986.1 313218 R 1134782 CDS YP_006767987.1 410480441 13690861 314169..314477 1 NC_018650.1 hypothetical protein 314477 13690861 O3M_01530 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767987.1 314169 D 1134782 CDS YP_006767988.1 410480442 13690862 314830..315129 1 NC_018650.1 COG1396 Predicted transcriptional regulators; transcriptional regulator 315129 13690862 O3M_01535 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006767988.1 314830 D 1134782 CDS YP_006767989.1 410480443 13690863 315693..317519 1 NC_018650.1 COG3593 Predicted ATP-dependent endonuclease of the OLD family; hypothetical protein 317519 13690863 O3M_01540 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767989.1 315693 D 1134782 CDS YP_006767990.1 410480444 13690864 complement(317688..318038) 1 NC_018650.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 318038 13690864 O3M_01545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767990.1 317688 R 1134782 CDS YP_006767991.1 410480445 13690865 complement(318186..318734) 1 NC_018650.1 silver-binding protein SilE 318734 13690865 O3M_01550 Escherichia coli O104:H4 str. 2009EL-2050 silver-binding protein SilE YP_006767991.1 318186 R 1134782 CDS YP_006767992.1 410480446 13690866 complement(318862..320343) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor kinase CusS 320343 13690866 O3M_01555 Escherichia coli O104:H4 str. 2009EL-2050 sensor kinase CusS YP_006767992.1 318862 R 1134782 CDS YP_006767993.1 410480447 13690867 complement(320336..321016) 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator CusR 321016 13690867 O3M_01560 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator CusR YP_006767993.1 320336 R 1134782 CDS YP_006767994.1 410480448 13690868 321206..322591 1 NC_018650.1 COG1538 Outer membrane protein; copper/silver efflux system outer membrane protein CusC 322591 13690868 O3M_01565 Escherichia coli O104:H4 str. 2009EL-2050 copper/silver efflux system outer membrane protein CusC YP_006767994.1 321206 D 1134782 CDS YP_006767995.1 410480449 13690869 322619..322972 1 NC_018650.1 COG5569 Uncharacterized conserved protein; copper-binding protein 322972 13690869 O3M_01570 Escherichia coli O104:H4 str. 2009EL-2050 copper-binding protein YP_006767995.1 322619 D 1134782 CDS YP_006767996.1 410480450 13690870 323086..324378 1 NC_018650.1 COG0845 Membrane-fusion protein; copper/silver efflux system membrane fusion protein CusB 324378 13690870 O3M_01575 Escherichia coli O104:H4 str. 2009EL-2050 copper/silver efflux system membrane fusion protein CusB YP_006767996.1 323086 D 1134782 CDS YP_006767997.1 410480451 13690871 324389..327535 1 NC_018650.1 COG3696 Putative silver efflux pump; Cu(I)/Ag(I) efflux system membrane protein CusA 327535 13690871 O3M_01580 Escherichia coli O104:H4 str. 2009EL-2050 Cu(I)/Ag(I) efflux system membrane protein CusA YP_006767997.1 324389 D 1134782 CDS YP_006767998.1 410480452 13690872 327622..328062 1 NC_018650.1 COG3019 Predicted metal-binding protein; hypothetical protein 328062 13690872 O3M_01585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006767998.1 327622 D 1134782 CDS YP_006767999.1 410480453 13690873 328189..330636 1 NC_018650.1 COG2217 Cation transport ATPase; cation-transporting P-type ATPase 330636 13690873 O3M_01590 Escherichia coli O104:H4 str. 2009EL-2050 cation-transporting P-type ATPase YP_006767999.1 328189 D 1134782 CDS YP_006768000.1 410480454 13690874 330677..330874 1 NC_018650.1 hypothetical protein 330874 13690874 O3M_01595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768000.1 330677 D 1134782 CDS YP_006768001.1 410480455 13690875 complement(330908..331645) 1 NC_018650.1 COG0739 Membrane proteins related to metalloendopeptidases; peptidase 331645 13690875 O3M_01600 Escherichia coli O104:H4 str. 2009EL-2050 peptidase YP_006768001.1 330908 R 1134782 CDS YP_006768002.1 410480456 13690876 331738..331824 1 NC_018650.1 hypothetical protein 331824 13690876 O3M_01605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768002.1 331738 D 1134782 CDS YP_006768003.1 410480457 13690877 complement(331934..332383) 1 NC_018650.1 copper resistant protein PcoE 332383 13690877 O3M_01610 Escherichia coli O104:H4 str. 2009EL-2050 copper resistant protein PcoE YP_006768003.1 331934 R 1134782 CDS YP_006768004.1 410480458 13690878 332618..334435 1 NC_018650.1 COG2132 Putative multicopper oxidases; copper resistant protein PcoA 334435 13690878 O3M_01615 Escherichia coli O104:H4 str. 2009EL-2050 copper resistant protein PcoA YP_006768004.1 332618 D 1134782 CDS YP_006768005.1 410480459 13690879 334432..335331 1 NC_018650.1 COG3667 Uncharacterized protein involved in copper resistance; copper resistance protein B 335331 13690879 O3M_01620 Escherichia coli O104:H4 str. 2009EL-2050 copper resistance protein B YP_006768005.1 334432 D 1134782 CDS YP_006768006.1 410480460 13690880 335371..335751 1 NC_018650.1 COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; copper resistant protein PcoC 335751 13690880 O3M_01625 Escherichia coli O104:H4 str. 2009EL-2050 copper resistant protein PcoC YP_006768006.1 335371 D 1134782 CDS YP_006768007.1 410480461 13690881 335756..336685 1 NC_018650.1 COG1276 Putative copper export protein; copper resistance protein D 336685 13690881 O3M_01630 Escherichia coli O104:H4 str. 2009EL-2050 copper resistance protein D YP_006768007.1 335756 D 1134782 CDS YP_006768008.1 410480462 13690882 336740..337420 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator PcoR 337420 13690882 O3M_01635 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator PcoR YP_006768008.1 336740 D 1134782 CDS YP_006768009.1 410480463 13690883 337417..338817 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor protein pcoS 338817 13690883 O3M_01640 Escherichia coli O104:H4 str. 2009EL-2050 sensor protein pcoS YP_006768009.1 337417 D 1134782 CDS YP_006768010.1 410480464 13690884 339035..339469 1 NC_018650.1 copper-binding protein 339469 13690884 O3M_01645 Escherichia coli O104:H4 str. 2009EL-2050 copper-binding protein YP_006768010.1 339035 D 1134782 CDS YP_006768011.1 410480465 13690885 complement(340129..341181) 1 NC_018650.1 hypothetical protein 341181 13690885 O3M_01650 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768011.1 340129 R 1134782 CDS YP_006768012.1 410480466 13690886 341566..342651 1 NC_018650.1 hypothetical protein 342651 13690886 O3M_01655 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768012.1 341566 D 1134782 CDS YP_006768013.1 410480467 13690887 342819..343190 1 NC_018650.1 hypothetical protein 343190 13690887 O3M_01660 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768013.1 342819 D 1134782 CDS YP_006768014.1 410480468 13690888 345439..346506 1 NC_018650.1 COG0845 Membrane-fusion protein; HlyD family secretion protein 346506 13690888 O3M_01675 Escherichia coli O104:H4 str. 2009EL-2050 HlyD family secretion protein YP_006768014.1 345439 D 1134782 CDS YP_006768015.1 410480469 13690889 346503..349238 1 NC_018650.1 ATP-binding protein; ATP-binding protein; membrane protein; COG1131 ABC-type multidrug transport system, ATPase component; ribosome-associated ATPase 349238 13690889 O3M_01680 Escherichia coli O104:H4 str. 2009EL-2050 ribosome-associated ATPase YP_006768015.1 346503 D 1134782 CDS YP_006768016.1 410480470 13690890 349238..350362 1 NC_018650.1 COG0842 ABC-type multidrug transport system, permease component; transporter subunit 350362 13690890 O3M_01685 Escherichia coli O104:H4 str. 2009EL-2050 transporter subunit YP_006768016.1 349238 D 1134782 CDS YP_006768017.1 410480471 13690891 350693..351052 1 NC_018650.1 COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters; HicB family protein 351052 13690891 O3M_01690 Escherichia coli O104:H4 str. 2009EL-2050 HicB family protein YP_006768017.1 350693 D 1134782 CDS YP_006768018.1 410480472 13690892 complement(351172..351573) 1 NC_018650.1 COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; nickel responsive regulator 351573 13690892 O3M_01695 Escherichia coli O104:H4 str. 2009EL-2050 nickel responsive regulator YP_006768018.1 351172 R 1134782 CDS YP_006768019.1 410480473 13690893 complement(351579..352385) 1 NC_018650.1 COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; nickel transporter ATP-binding protein NikE 352385 nikE 13690893 nikE Escherichia coli O104:H4 str. 2009EL-2050 nickel transporter ATP-binding protein NikE YP_006768019.1 351579 R 1134782 CDS YP_006768020.1 410480474 13690894 complement(352382..353146) 1 NC_018650.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; nickel transporter ATP-binding protein NikD 353146 nikD 13690894 nikD Escherichia coli O104:H4 str. 2009EL-2050 nickel transporter ATP-binding protein NikD YP_006768020.1 352382 R 1134782 CDS YP_006768021.1 410480475 13690895 complement(353146..353979) 1 NC_018650.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; nickel transporter permease NikC 353979 nikC 13690895 nikC Escherichia coli O104:H4 str. 2009EL-2050 nickel transporter permease NikC YP_006768021.1 353146 R 1134782 CDS YP_006768022.1 410480476 13690896 complement(353976..354920) 1 NC_018650.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; nickel transporter permease NikB 354920 13690896 O3M_01715 Escherichia coli O104:H4 str. 2009EL-2050 nickel transporter permease NikB YP_006768022.1 353976 R 1134782 CDS YP_006768023.1 410480477 13690897 complement(354920..356494) 1 NC_018650.1 COG0747 ABC-type dipeptide transport system, periplasmic component; periplasmic binding protein for nickel NikA 356494 13690897 O3M_01720 Escherichia coli O104:H4 str. 2009EL-2050 periplasmic binding protein for nickel NikA YP_006768023.1 354920 R 1134782 CDS YP_006768024.1 410480478 13690898 complement(356605..357192) 1 NC_018650.1 COG2091 Phosphopantetheinyl transferase; holo-(acyl carrier protein) synthase 2 357192 13690898 O3M_01725 Escherichia coli O104:H4 str. 2009EL-2050 holo-(acyl carrier protein) synthase 2 YP_006768024.1 356605 R 1134782 CDS YP_006768025.1 410480479 13690899 complement(357247..358296) 1 NC_018650.1 COG0628 Predicted permease; inner membrane protein 358296 13690899 O3M_01730 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768025.1 357247 R 1134782 CDS YP_006768026.1 410480480 13690900 358428..359645 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily transporter 359645 13690900 O3M_01735 Escherichia coli O104:H4 str. 2009EL-2050 major facilitator superfamily transporter YP_006768026.1 358428 D 1134782 CDS YP_006768027.1 410480481 13690901 complement(359649..360206) 1 NC_018650.1 hypothetical protein 360206 13690901 O3M_01740 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768027.1 359649 R 1134782 CDS YP_006768028.1 410480482 13690902 complement(360279..360944) 1 NC_018650.1 COG1738 Uncharacterized conserved protein; hypothetical protein 360944 13690902 O3M_01745 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768028.1 360279 R 1134782 CDS YP_006768029.1 410480483 13690903 361165..361410 1 NC_018650.1 COG0425 Predicted redox protein, regulator of disulfide bond formation; sulfur transfer protein SirA 361410 13690903 O3M_01750 Escherichia coli O104:H4 str. 2009EL-2050 sulfur transfer protein SirA YP_006768029.1 361165 D 1134782 CDS YP_006768030.1 410480484 13690904 complement(361512..363710) 1 NC_018650.1 COG2217 Cation transport ATPase; zinc/cadmium/mercury/lead-transporting ATPase 363710 zntA 13690904 zntA Escherichia coli O104:H4 str. 2009EL-2050 zinc/cadmium/mercury/lead-transporting ATPase YP_006768030.1 361512 R 1134782 CDS YP_006768031.1 410480485 13690905 complement(363784..364410) 1 NC_018650.1 COG3714 Predicted membrane protein; hypothetical protein 364410 13690905 O3M_01760 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768031.1 363784 R 1134782 CDS YP_006768032.1 410480486 13690906 364551..364910 1 NC_018650.1 hypothetical protein 364910 13690906 O3M_01765 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768032.1 364551 D 1134782 CDS YP_006768033.1 410480487 13690907 complement(364913..365182) 1 NC_018650.1 COG3776 Predicted membrane protein; hypothetical protein 365182 13690907 O3M_01770 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768033.1 364913 R 1134782 CDS YP_006768034.1 410480488 13690908 complement(365172..365768) 1 NC_018650.1 COG0742 N6-adenine-specific methylase; 16S rRNA m(2)G966-methyltransferase 365768 rsmD 13690908 rsmD Escherichia coli O104:H4 str. 2009EL-2050 16S rRNA m(2)G966-methyltransferase YP_006768034.1 365172 R 1134782 CDS YP_006768035.1 410480489 13690909 365918..367411 1 NC_018650.1 COG0552 Signal recognition particle GTPase; signal recognition particle-docking protein FtsY 367411 13690909 O3M_01780 Escherichia coli O104:H4 str. 2009EL-2050 signal recognition particle-docking protein FtsY YP_006768035.1 365918 D 1134782 CDS YP_006768036.1 410480490 13690910 367414..368082 1 NC_018650.1 COG2884 Predicted ATPase involved in cell division; cell division protein FtsE 368082 13690910 O3M_01785 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsE YP_006768036.1 367414 D 1134782 CDS YP_006768037.1 410480491 13690911 368075..369133 1 NC_018650.1 COG2177 Cell division protein; cell division ABC transporter subunit FtsX 369133 ftsX 13690911 ftsX Escherichia coli O104:H4 str. 2009EL-2050 cell division ABC transporter subunit FtsX YP_006768037.1 368075 D 1134782 CDS YP_006768038.1 410480492 13690912 369378..370232 1 NC_018650.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase factor sigma-32 370232 13690912 O3M_01795 Escherichia coli O104:H4 str. 2009EL-2050 RNA polymerase factor sigma-32 YP_006768038.1 369378 D 1134782 CDS YP_006768039.1 410480493 13690913 370503..371606 1 NC_018650.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; leucine ABC transporter subunit substrate-binding protein LivK 371606 13690913 O3M_01800 Escherichia coli O104:H4 str. 2009EL-2050 leucine ABC transporter subunit substrate-binding protein LivK YP_006768039.1 370503 D 1134782 CDS YP_006768040.1 410480494 13690914 complement(371662..371796) 1 NC_018650.1 hypothetical protein 371796 13690914 O3M_01805 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768040.1 371662 R 1134782 CDS YP_006768041.1 410480495 13690915 complement(371805..372188) 1 NC_018650.1 hypothetical protein 372188 13690915 O3M_01810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768041.1 371805 R 1134782 CDS YP_006768042.1 410480496 13690916 372612..373721 1 NC_018650.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; leucine ABC transporter subunit substrate-binding protein LivK 373721 13690916 O3M_01815 Escherichia coli O104:H4 str. 2009EL-2050 leucine ABC transporter subunit substrate-binding protein LivK YP_006768042.1 372612 D 1134782 CDS YP_006768043.1 410480497 13690917 373769..374695 1 NC_018650.1 COG0559 Branched-chain amino acid ABC-type transport system, permease components; branched-chain amino acid transporter permease LivH 374695 13690917 O3M_01820 Escherichia coli O104:H4 str. 2009EL-2050 branched-chain amino acid transporter permease LivH YP_006768043.1 373769 D 1134782 CDS YP_006768044.1 410480498 13690918 374692..375969 1 NC_018650.1 COG4177 ABC-type branched-chain amino acid transport system, permease component; leucine/isoleucine/valine transporter permease subunit 375969 livM 13690918 livM Escherichia coli O104:H4 str. 2009EL-2050 leucine/isoleucine/valine transporter permease subunit YP_006768044.1 374692 D 1134782 CDS YP_006768045.1 410480499 13690919 375966..376733 1 NC_018650.1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; leucine/isoleucine/valine transporter ATP-binding subunit 376733 livG 13690919 livG Escherichia coli O104:H4 str. 2009EL-2050 leucine/isoleucine/valine transporter ATP-binding subunit YP_006768045.1 375966 D 1134782 CDS YP_006768046.1 410480500 13690920 376747..377448 1 NC_018650.1 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; leucine/isoleucine/valine transporter ATP-binding subunit 377448 livF 13690920 livF Escherichia coli O104:H4 str. 2009EL-2050 leucine/isoleucine/valine transporter ATP-binding subunit YP_006768046.1 376747 D 1134782 CDS YP_006768047.1 410480501 13690921 377484..377612 1 NC_018650.1 hypothetical protein 377612 13690921 O3M_01840 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768047.1 377484 D 1134782 CDS YP_006768048.1 410480502 13690922 377844..379160 1 NC_018650.1 COG1653 ABC-type sugar transport system, periplasmic component; glycerol-3-phosphate transporter periplasmic binding protein 379160 13690922 O3M_01845 Escherichia coli O104:H4 str. 2009EL-2050 glycerol-3-phosphate transporter periplasmic binding protein YP_006768048.1 377844 D 1134782 CDS YP_006768049.1 410480503 13690923 379258..380145 1 NC_018650.1 COG1175 ABC-type sugar transport systems, permease components; glycerol-3-phosphate transporter permease 380145 13690923 O3M_01850 Escherichia coli O104:H4 str. 2009EL-2050 glycerol-3-phosphate transporter permease YP_006768049.1 379258 D 1134782 CDS YP_006768050.1 410480504 13690924 380142..380987 1 NC_018650.1 COG0395 ABC-type sugar transport system, permease component; glycerol-3-phosphate transporter membrane protein 380987 13690924 O3M_01855 Escherichia coli O104:H4 str. 2009EL-2050 glycerol-3-phosphate transporter membrane protein YP_006768050.1 380142 D 1134782 CDS YP_006768051.1 410480505 13690925 380989..382059 1 NC_018650.1 COG3839 ABC-type sugar transport systems, ATPase components; glycerol-3-phosphate transporter ATP-binding subunit 382059 ugpC 13690925 ugpC Escherichia coli O104:H4 str. 2009EL-2050 glycerol-3-phosphate transporter ATP-binding subunit YP_006768051.1 380989 D 1134782 CDS YP_006768052.1 410480506 13690926 382056..382799 1 NC_018650.1 COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphodiester phosphodiesterase 382799 ugpQ 13690926 ugpQ Escherichia coli O104:H4 str. 2009EL-2050 glycerophosphodiester phosphodiesterase YP_006768052.1 382056 D 1134782 CDS YP_006768053.1 410480507 13690927 complement(382786..383226) 1 NC_018650.1 hypothetical protein 383226 13690927 O3M_01870 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768053.1 382786 R 1134782 CDS YP_006768054.1 410480508 13690928 383346..385088 1 NC_018650.1 COG0405 Gamma-glutamyltransferase; gamma-glutamyltranspeptidase 385088 ggt 13690928 ggt Escherichia coli O104:H4 str. 2009EL-2050 gamma-glutamyltranspeptidase YP_006768054.1 383346 D 1134782 CDS YP_006768055.1 410480509 13690929 complement(385126..385410) 1 NC_018650.1 hypothetical protein 385410 13690929 O3M_01880 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768055.1 385126 R 1134782 CDS YP_006768056.1 410480510 13690930 complement(385860..386354) 1 NC_018650.1 hypothetical protein 386354 13690930 O3M_01885 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768056.1 385860 R 1134782 CDS YP_006768057.1 410480511 13690931 complement(386351..387529) 1 NC_018650.1 COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein 387529 13690931 O3M_01890 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768057.1 386351 R 1134782 CDS YP_006768058.1 410480512 13690932 complement(387766..388254) 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase YhhY 388254 13690932 O3M_01895 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YhhY YP_006768058.1 387766 R 1134782 CDS YP_006768059.1 410480513 13690933 388586..389623 1 NC_018650.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 389623 13690933 O3M_01900 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006768059.1 388586 D 1134782 CDS YP_006768060.1 410480514 13690934 389746..390441 1 NC_018650.1 COG1741 Pirin-related protein; protein yhhW 390441 13690934 O3M_01905 Escherichia coli O104:H4 str. 2009EL-2050 protein yhhW YP_006768060.1 389746 D 1134782 CDS YP_006768061.1 410480515 13690935 390665..391660 1 NC_018650.1 COG1609 Transcriptional regulators; gluconate operon transcriptional regulator 391660 13690935 O3M_01910 Escherichia coli O104:H4 str. 2009EL-2050 gluconate operon transcriptional regulator YP_006768061.1 390665 D 1134782 CDS YP_006768062.1 410480516 13690936 391799..392326 1 NC_018650.1 COG3265 Gluconate kinase; gluconate kinase 392326 gntK 13690936 gntK Escherichia coli O104:H4 str. 2009EL-2050 gluconate kinase YP_006768062.1 391799 D 1134782 CDS YP_006768063.1 410480517 13690937 392330..393670 1 NC_018650.1 COG2610 H+/gluconate symporter and related permeases; low affinity gluconate transporter 393670 13690937 O3M_01920 Escherichia coli O104:H4 str. 2009EL-2050 low affinity gluconate transporter YP_006768063.1 392330 D 1134782 CDS YP_006768064.1 410480518 13690938 complement(393727..394320) 1 NC_018650.1 COG2095 Multiple antibiotic transporter; antibiotic transporter 394320 13690938 O3M_01925 Escherichia coli O104:H4 str. 2009EL-2050 antibiotic transporter YP_006768064.1 393727 R 1134782 CDS YP_006768065.1 410480519 13690939 394513..395616 1 NC_018650.1 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 395616 13690939 O3M_01930 Escherichia coli O104:H4 str. 2009EL-2050 aspartate-semialdehyde dehydrogenase YP_006768065.1 394513 D 1134782 CDS YP_006768066.1 410480520 13690940 395889..398075 1 NC_018650.1 COG0296 1,4-alpha-glucan branching enzyme; glycogen branching protein 398075 13690940 O3M_01935 Escherichia coli O104:H4 str. 2009EL-2050 glycogen branching protein YP_006768066.1 395889 D 1134782 CDS YP_006768067.1 410480521 13690941 398072..400045 1 NC_018650.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen debranching protein 400045 13690941 O3M_01940 Escherichia coli O104:H4 str. 2009EL-2050 glycogen debranching protein YP_006768067.1 398072 D 1134782 CDS YP_006768068.1 410480522 13690942 400063..401358 1 NC_018650.1 COG0448 ADP-glucose pyrophosphorylase; glucose-1-phosphate adenylyltransferase 401358 glgC 13690942 glgC Escherichia coli O104:H4 str. 2009EL-2050 glucose-1-phosphate adenylyltransferase YP_006768068.1 400063 D 1134782 CDS YP_006768069.1 410480523 13690943 401358..402791 1 NC_018650.1 COG0297 Glycogen synthase; glycogen synthase 402791 glgA 13690943 glgA Escherichia coli O104:H4 str. 2009EL-2050 glycogen synthase YP_006768069.1 401358 D 1134782 CDS YP_006768070.1 410480524 13690944 402810..405257 1 NC_018650.1 COG0058 Glucan phosphorylase; glycogen phosphorylase 405257 13690944 O3M_01955 Escherichia coli O104:H4 str. 2009EL-2050 glycogen phosphorylase YP_006768070.1 402810 D 1134782 CDS YP_006768071.1 410480525 13690945 405373..406890 1 NC_018650.1 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate transport system substrate-binding protein 406890 13690945 O3M_01960 Escherichia coli O104:H4 str. 2009EL-2050 phosphate transport system substrate-binding protein YP_006768071.1 405373 D 1134782 CDS YP_006768072.1 410480526 13690946 406906..407616 1 NC_018650.1 hypothetical protein 407616 13690946 O3M_01965 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768072.1 406906 D 1134782 CDS YP_006768073.1 410480527 13690947 407619..408386 1 NC_018650.1 hypothetical protein 408386 13690947 O3M_01970 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768073.1 407619 D 1134782 CDS YP_006768074.1 410480528 13690948 408389..408994 1 NC_018650.1 hypothetical protein 408994 13690948 O3M_01975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768074.1 408389 D 1134782 CDS YP_006768075.1 410480529 13690949 complement(409046..410551) 1 NC_018650.1 COG0578 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 410551 glpD 13690949 glpD Escherichia coli O104:H4 str. 2009EL-2050 glycerol-3-phosphate dehydrogenase YP_006768075.1 409046 R 1134782 CDS YP_006768076.1 410480530 13690950 410741..411067 1 NC_018650.1 COG0607 Rhodanese-related sulfurtransferase; thiosulfate sulfurtransferase 411067 glpE 13690950 glpE Escherichia coli O104:H4 str. 2009EL-2050 thiosulfate sulfurtransferase YP_006768076.1 410741 D 1134782 CDS YP_006768077.1 410480531 13690951 411112..411942 1 NC_018650.1 COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); intramembrane serine protease GlpG 411942 13690951 O3M_01990 Escherichia coli O104:H4 str. 2009EL-2050 intramembrane serine protease GlpG YP_006768077.1 411112 D 1134782 CDS YP_006768078.1 410480532 13690952 411959..412717 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor GlpR 412717 13690952 O3M_01995 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor GlpR YP_006768078.1 411959 D 1134782 CDS YP_006768079.1 410480533 13690953 complement(412699..414297) 1 NC_018650.1 COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain; sigma 54-dependent transcriptional regulator of rtcBA expression 414297 13690953 O3M_02000 Escherichia coli O104:H4 str. 2009EL-2050 sigma 54-dependent transcriptional regulator of rtcBA expression YP_006768079.1 412699 R 1134782 CDS YP_006768080.1 410480534 13690954 414486..415712 1 NC_018650.1 COG1690 Uncharacterized conserved protein; hypothetical protein 415712 13690954 O3M_02005 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768080.1 414486 D 1134782 CDS YP_006768081.1 410480535 13690955 415716..416732 1 NC_018650.1 COG0430 RNA 3'-terminal phosphate cyclase; RNA 3'-terminal-phosphate cyclase 416732 13690955 O3M_02010 Escherichia coli O104:H4 str. 2009EL-2050 RNA 3'-terminal-phosphate cyclase YP_006768081.1 415716 D 1134782 CDS YP_006768082.1 410480536 13690956 complement(416775..419480) 1 NC_018650.1 COG2909 ATP-dependent transcriptional regulator; transcriptional regulator MalT 419480 13690956 O3M_02015 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator MalT YP_006768082.1 416775 R 1134782 CDS YP_006768083.1 410480537 13690957 420092..422485 1 NC_018650.1 COG0058 Glucan phosphorylase; maltodextrin phosphorylase 422485 13690957 O3M_02020 Escherichia coli O104:H4 str. 2009EL-2050 maltodextrin phosphorylase YP_006768083.1 420092 D 1134782 CDS YP_006768084.1 410480538 13690958 422495..424579 1 NC_018650.1 COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 424579 malQ 13690958 malQ Escherichia coli O104:H4 str. 2009EL-2050 4-alpha-glucanotransferase YP_006768084.1 422495 D 1134782 CDS YP_006768085.1 410480539 13690959 complement(424624..425940) 1 NC_018650.1 COG2610 H+/gluconate symporter and related permeases; high-affinity gluconate transporter 425940 13690959 O3M_02030 Escherichia coli O104:H4 str. 2009EL-2050 high-affinity gluconate transporter YP_006768085.1 424624 R 1134782 CDS YP_006768086.1 410480540 13690960 complement(426301..426876) 1 NC_018650.1 COG0316 Uncharacterized conserved protein; Fe/S biogenesis protein NfuA 426876 13690960 O3M_02035 Escherichia coli O104:H4 str. 2009EL-2050 Fe/S biogenesis protein NfuA YP_006768086.1 426301 R 1134782 CDS YP_006768087.1 410480541 13690961 complement(426935..427618) 1 NC_018650.1 COG1040 Predicted amidophosphoribosyltransferases; DNA utilization protein GntX 427618 13690961 O3M_02040 Escherichia coli O104:H4 str. 2009EL-2050 DNA utilization protein GntX YP_006768087.1 426935 R 1134782 CDS YP_006768088.1 410480542 13690962 427656..428426 1 NC_018650.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); carboxylesterase BioH 428426 13690962 O3M_02045 Escherichia coli O104:H4 str. 2009EL-2050 carboxylesterase BioH YP_006768088.1 427656 D 1134782 CDS YP_006768089.1 410480543 13690963 complement(428455..429333) 1 NC_018650.1 transposase 429333 13690963 O3M_02050 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768089.1 428455 R 1134782 CDS YP_006768090.1 410480544 13690964 complement(429536..429772) 1 NC_018650.1 ferrous iron transport protein FeoC 429772 13690964 O3M_02055 Escherichia coli O104:H4 str. 2009EL-2050 ferrous iron transport protein FeoC YP_006768090.1 429536 R 1134782 CDS YP_006768091.1 410480545 13690965 complement(429772..432093) 1 NC_018650.1 COG0370 Fe2+ transport system protein B; ferrous iron transport protein B 432093 feoB 13690965 feoB Escherichia coli O104:H4 str. 2009EL-2050 ferrous iron transport protein B YP_006768091.1 429772 R 1134782 CDS YP_006768092.1 410480546 13690966 complement(432110..432337) 1 NC_018650.1 COG1918 Fe2+ transport system protein A; ferrous iron transport protein A 432337 feoA 13690966 feoA Escherichia coli O104:H4 str. 2009EL-2050 ferrous iron transport protein A YP_006768092.1 432110 R 1134782 CDS YP_006768093.1 410480547 13690967 complement(432775..435096) 1 NC_018650.1 COG2183 Transcriptional accessory protein; transcriptional accessory protein 435096 13690967 O3M_02070 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional accessory protein YP_006768093.1 432775 R 1134782 CDS YP_006768094.1 410480548 13690968 complement(435193..435669) 1 NC_018650.1 COG0782 Transcription elongation factor; transcription elongation factor GreB 435669 greB 13690968 greB Escherichia coli O104:H4 str. 2009EL-2050 transcription elongation factor GreB YP_006768094.1 435193 R 1134782 CDS YP_006768095.1 410480549 13690969 435897..436616 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; osmolarity response regulator 436616 ompR 13690969 ompR Escherichia coli O104:H4 str. 2009EL-2050 osmolarity response regulator YP_006768095.1 435897 D 1134782 CDS YP_006768096.1 410480550 13690970 436613..437965 1 NC_018650.1 COG0642 Signal transduction histidine kinase; osmolarity sensor protein 437965 envZ 13690970 envZ Escherichia coli O104:H4 str. 2009EL-2050 osmolarity sensor protein YP_006768096.1 436613 D 1134782 CDS YP_006768097.1 410480551 13690971 complement(437995..438291) 1 NC_018650.1 COG2944 Predicted transcriptional regulator; HTH-type transcriptional regulator yiaG 438291 13690971 O3M_02090 Escherichia coli O104:H4 str. 2009EL-2050 HTH-type transcriptional regulator yiaG YP_006768097.1 437995 R 1134782 CDS YP_006768098.1 410480552 13690972 complement(438350..438667) 1 NC_018650.1 COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; hypothetical protein 438667 13690972 O3M_02095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768098.1 438350 R 1134782 CDS YP_006768099.1 410480553 13690973 complement(438784..440406) 1 NC_018650.1 COG1866 Phosphoenolpyruvate carboxykinase (ATP); phosphoenolpyruvate carboxykinase 440406 13690973 O3M_02100 Escherichia coli O104:H4 str. 2009EL-2050 phosphoenolpyruvate carboxykinase YP_006768099.1 438784 R 1134782 CDS YP_006768100.1 410480554 13690974 440785..442509 1 NC_018650.1 inner membrane protein 442509 13690974 O3M_02105 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768100.1 440785 D 1134782 CDS YP_006768101.1 410480555 13690975 complement(442644..443522) 1 NC_018650.1 COG1281 Disulfide bond chaperones of the HSP33 family; Hsp33-like chaperonin 443522 hslO 13690975 hslO Escherichia coli O104:H4 str. 2009EL-2050 Hsp33-like chaperonin YP_006768101.1 442644 R 1134782 CDS YP_006768102.1 410480556 13690976 complement(443547..443948) 1 NC_018650.1 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); ribosome-associated heat shock protein Hsp15 443948 13690976 O3M_02115 Escherichia coli O104:H4 str. 2009EL-2050 ribosome-associated heat shock protein Hsp15 YP_006768102.1 443547 R 1134782 CDS YP_006768103.1 410480557 13690977 complement(443959..444627) 1 NC_018650.1 COG1011 Predicted hydrolase (HAD superfamily); GMP/IMP nucleotidase 444627 13690977 O3M_02120 Escherichia coli O104:H4 str. 2009EL-2050 GMP/IMP nucleotidase YP_006768103.1 443959 R 1134782 CDS YP_006768104.1 410480558 13690978 complement(444692..446827) 1 NC_018650.1 intracellular growth attenuator protein 446827 13690978 O3M_02125 Escherichia coli O104:H4 str. 2009EL-2050 intracellular growth attenuator protein YP_006768104.1 444692 R 1134782 CDS YP_006768105.1 410480559 13690979 447147..447707 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; adenosine nucleotide hydrolase NudE 447707 nudE 13690979 nudE Escherichia coli O104:H4 str. 2009EL-2050 adenosine nucleotide hydrolase NudE YP_006768105.1 447147 D 1134782 CDS YP_006768106.1 410480560 13690980 complement(447875..450427) 1 NC_018650.1 COG5009 Membrane carboxypeptidase/penicillin-binding protein; penicillin-binding protein 1a 450427 mrcA 13690980 mrcA Escherichia coli O104:H4 str. 2009EL-2050 penicillin-binding protein 1a YP_006768106.1 447875 R 1134782 CDS YP_006768107.1 410480561 13690981 450547..451326 1 NC_018650.1 pilus assembly protein 451326 13690981 O3M_02140 Escherichia coli O104:H4 str. 2009EL-2050 pilus assembly protein YP_006768107.1 450547 D 1134782 CDS YP_006768108.1 410480562 13690982 451326..451865 1 NC_018650.1 fimbrial assembly protein 451865 13690982 O3M_02145 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial assembly protein YP_006768108.1 451326 D 1134782 CDS YP_006768109.1 410480563 13690983 451849..452289 1 NC_018650.1 hypothetical protein 452289 13690983 O3M_02150 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768109.1 451849 D 1134782 CDS YP_006768110.1 410480564 13690984 452279..452683 1 NC_018650.1 hypothetical protein 452683 13690984 O3M_02155 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768110.1 452279 D 1134782 CDS YP_006768111.1 410480565 13690985 452595..453833 1 NC_018650.1 COG4796 Type II secretory pathway, component HofQ; outer membrane porin HofQ 453833 hofQ 13690985 hofQ Escherichia coli O104:H4 str. 2009EL-2050 outer membrane porin HofQ YP_006768111.1 452595 D 1134782 CDS YP_006768112.1 410480566 13690986 454234..454755 1 NC_018650.1 COG0703 Shikimate kinase; shikimate kinase I 454755 aroK 13690986 aroK Escherichia coli O104:H4 str. 2009EL-2050 shikimate kinase I YP_006768112.1 454234 D 1134782 CDS YP_006768113.1 410480567 13690987 454812..455900 1 NC_018650.1 COG0337 3-dehydroquinate synthetase; 3-dehydroquinate synthase 455900 aroB 13690987 aroB Escherichia coli O104:H4 str. 2009EL-2050 3-dehydroquinate synthase YP_006768113.1 454812 D 1134782 CDS YP_006768114.1 410480568 13690988 455992..457278 1 NC_018650.1 COG3266 Uncharacterized protein conserved in bacteria; cell division protein DamX 457278 13690988 O3M_02175 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein DamX YP_006768114.1 455992 D 1134782 CDS YP_006768115.1 410480569 13690989 457385..458221 1 NC_018650.1 COG0338 Site-specific DNA methylase; DNA adenine methylase 458221 13690989 O3M_02180 Escherichia coli O104:H4 str. 2009EL-2050 DNA adenine methylase YP_006768115.1 457385 D 1134782 CDS YP_006768116.1 410480570 13690990 458239..458916 1 NC_018650.1 COG0036 Pentose-5-phosphate-3-epimerase; ribulose-phosphate 3-epimerase 458916 13690990 O3M_02185 Escherichia coli O104:H4 str. 2009EL-2050 ribulose-phosphate 3-epimerase YP_006768116.1 458239 D 1134782 CDS YP_006768117.1 410480571 13690991 458909..459667 1 NC_018650.1 COG0546 Predicted phosphatases; phosphoglycolate phosphatase 459667 13690991 O3M_02190 Escherichia coli O104:H4 str. 2009EL-2050 phosphoglycolate phosphatase YP_006768117.1 458909 D 1134782 CDS YP_006768118.1 410480572 13690992 459660..460664 1 NC_018650.1 COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 460664 13690992 O3M_02195 Escherichia coli O104:H4 str. 2009EL-2050 tryptophanyl-tRNA synthetase YP_006768118.1 459660 D 1134782 CDS YP_006768119.1 410480573 13690993 460933..461838 1 NC_018650.1 hypothetical protein 461838 13690993 O3M_02200 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768119.1 460933 D 1134782 CDS YP_006768120.1 410480574 13690994 461855..462217 1 NC_018650.1 hypothetical protein 462217 13690994 O3M_02205 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768120.1 461855 D 1134782 CDS YP_006768121.1 410480575 13690995 462301..463464 1 NC_018650.1 COG3457 Predicted amino acid racemase; amino acid racemase 463464 13690995 O3M_02210 Escherichia coli O104:H4 str. 2009EL-2050 amino acid racemase YP_006768121.1 462301 D 1134782 CDS YP_006768122.1 410480576 13690996 463464..464690 1 NC_018650.1 COG1015 Phosphopentomutase; mutase 464690 13690996 O3M_02215 Escherichia coli O104:H4 str. 2009EL-2050 mutase YP_006768122.1 463464 D 1134782 CDS YP_006768123.1 410480577 13690997 464687..465565 1 NC_018650.1 COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold; hydrolase 465565 13690997 O3M_02220 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006768123.1 464687 D 1134782 CDS YP_006768124.1 410480578 13690998 465576..465929 1 NC_018650.1 COG0698 Ribose 5-phosphate isomerase RpiB; hypothetical protein 465929 13690998 O3M_02225 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768124.1 465576 D 1134782 CDS YP_006768125.1 410480579 13690999 465941..467245 1 NC_018650.1 inner membrane protein 467245 13690999 O3M_02230 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768125.1 465941 D 1134782 CDS YP_006768126.1 410480580 13691000 467257..468342 1 NC_018650.1 hypothetical protein 468342 13691000 O3M_02235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768126.1 467257 D 1134782 CDS YP_006768127.1 410480581 13691001 complement(468494..469225) 1 NC_018650.1 COG2188 Transcriptional regulators; DNA-binding transcriptional regulator FrlR 469225 13691001 O3M_02240 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator FrlR YP_006768127.1 468494 R 1134782 CDS YP_006768128.1 410480582 13691002 complement(469325..470110) 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; fructoselysine 6-kinase 470110 13691002 O3M_02245 Escherichia coli O104:H4 str. 2009EL-2050 fructoselysine 6-kinase YP_006768128.1 469325 R 1134782 CDS YP_006768129.1 410480583 13691003 complement(470107..470937) 1 NC_018650.1 COG1082 Sugar phosphate isomerases/epimerases; fructoselysine 3-epimerase 470937 13691003 O3M_02250 Escherichia coli O104:H4 str. 2009EL-2050 fructoselysine 3-epimerase YP_006768129.1 470107 R 1134782 CDS YP_006768130.1 410480584 13691004 complement(470987..472009) 1 NC_018650.1 COG2222 Predicted phosphosugar isomerases; fructoselysine-6-P-deglycase 472009 frlB 13691004 frlB Escherichia coli O104:H4 str. 2009EL-2050 fructoselysine-6-P-deglycase YP_006768130.1 470987 R 1134782 CDS YP_006768131.1 410480585 13691005 complement(472030..473367) 1 NC_018650.1 COG0531 Amino acid transporters; fructoselysine transporter 473367 frlA 13691005 frlA Escherichia coli O104:H4 str. 2009EL-2050 fructoselysine transporter YP_006768131.1 472030 R 1134782 CDS YP_006768132.1 410480586 13691006 complement(473662..473829) 1 NC_018650.1 lipoprotein 473829 13691006 O3M_02265 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006768132.1 473662 R 1134782 CDS YP_006768133.1 410480587 13691007 complement(474076..475449) 1 NC_018650.1 COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); siroheme synthase 475449 cysG 13691007 cysG Escherichia coli O104:H4 str. 2009EL-2050 siroheme synthase YP_006768133.1 474076 R 1134782 CDS YP_006768134.1 410480588 13691008 complement(475468..476274) 1 NC_018650.1 COG2116 Formate/nitrite family of transporters; nitrite transporter NirC 476274 13691008 O3M_02275 Escherichia coli O104:H4 str. 2009EL-2050 nitrite transporter NirC YP_006768134.1 475468 R 1134782 CDS YP_006768135.1 410480589 13691009 complement(476401..476727) 1 NC_018650.1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; nitrite reductase small subunit 476727 nirD 13691009 nirD Escherichia coli O104:H4 str. 2009EL-2050 nitrite reductase small subunit YP_006768135.1 476401 R 1134782 CDS YP_006768136.1 410480590 13691010 complement(476724..479267) 1 NC_018650.1 COG1251 NAD(P)H-nitrite reductase; nitrite reductase subunit NirD 479267 13691010 O3M_02285 Escherichia coli O104:H4 str. 2009EL-2050 nitrite reductase subunit NirD YP_006768136.1 476724 R 1134782 CDS YP_006768137.1 410480591 13691011 complement(479529..480710) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 480710 13691011 O3M_02290 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768137.1 479529 R 1134782 CDS YP_006768138.1 410480592 13691012 480981..481553 1 NC_018650.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase A 481553 13691012 O3M_02295 Escherichia coli O104:H4 str. 2009EL-2050 peptidyl-prolyl cis-trans isomerase A YP_006768138.1 480981 D 1134782 CDS YP_006768139.1 410480593 13691013 481658..481825 1 NC_018650.1 hypothetical protein 481825 13691013 O3M_02300 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768139.1 481658 D 1134782 CDS YP_006768140.1 410480594 13691014 481815..482417 1 NC_018650.1 COG2184 Protein involved in cell division; cell filamentation protein Fic 482417 13691014 O3M_02305 Escherichia coli O104:H4 str. 2009EL-2050 cell filamentation protein Fic YP_006768140.1 481815 D 1134782 CDS YP_006768141.1 410480595 13691015 482449..483012 1 NC_018650.1 COG0512 Anthranilate/para-aminobenzoate synthases component II; para-aminobenzoate synthase component II 483012 13691015 O3M_02310 Escherichia coli O104:H4 str. 2009EL-2050 para-aminobenzoate synthase component II YP_006768141.1 482449 D 1134782 CDS YP_006768142.1 410480596 13691016 483098..484318 1 NC_018650.1 COG4992 Ornithine/acetylornithine aminotransferase; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 484318 argD 13691016 argD Escherichia coli O104:H4 str. 2009EL-2050 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase YP_006768142.1 483098 D 1134782 CDS YP_006768143.1 410480597 13691017 complement(484385..486475) 1 NC_018650.1 COG1289 Predicted membrane protein; hypothetical protein 486475 13691017 O3M_02320 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768143.1 484385 R 1134782 CDS YP_006768144.1 410480598 13691018 complement(486526..487158) 1 NC_018650.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; DNA-binding transcriptional dual regulator Crp 487158 13691018 O3M_02325 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional dual regulator Crp YP_006768144.1 486526 R 1134782 CDS YP_006768145.1 410480599 13691019 487460..487864 1 NC_018650.1 COG1765 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 487864 13691019 O3M_02330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768145.1 487460 D 1134782 CDS YP_006768146.1 410480600 13691020 complement(487919..488788) 1 NC_018650.1 COG3954 Phosphoribulokinase; phosphoribulokinase 488788 13691020 O3M_02335 Escherichia coli O104:H4 str. 2009EL-2050 phosphoribulokinase YP_006768146.1 487919 R 1134782 CDS YP_006768147.1 410480601 13691021 complement(488842..489060) 1 NC_018650.1 COG3089 Uncharacterized protein conserved in bacteria; hypothetical protein 489060 13691021 O3M_02340 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768147.1 488842 R 1134782 CDS YP_006768148.1 410480602 13691022 complement(489054..490076) 1 NC_018650.1 COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold; hydrolase 490076 13691022 O3M_02345 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006768148.1 489054 R 1134782 CDS YP_006768149.1 410480603 13691023 complement(490076..491989) 1 NC_018650.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 491989 13691023 O3M_02350 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006768149.1 490076 R 1134782 CDS YP_006768150.1 410480604 13691024 492120..492671 1 NC_018650.1 COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); glutathione-regulated potassium-efflux system ancillary protein KefG 492671 13691024 O3M_02355 Escherichia coli O104:H4 str. 2009EL-2050 glutathione-regulated potassium-efflux system ancillary protein KefG YP_006768150.1 492120 D 1134782 CDS YP_006768151.1 410480605 13691025 492671..494476 1 NC_018650.1 COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefB 494476 13691025 O3M_02360 Escherichia coli O104:H4 str. 2009EL-2050 glutathione-regulated potassium-efflux system protein KefB YP_006768151.1 492671 D 1134782 CDS YP_006768152.1 410480606 13691026 494486..494686 1 NC_018650.1 COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain; hypothetical protein 494686 13691026 O3M_02365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768152.1 494486 D 1134782 CDS YP_006768153.1 410480607 13691027 494781..495371 1 NC_018650.1 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; FKBP-type peptidyl-prolyl cis-trans isomerase 495371 13691027 O3M_02370 Escherichia coli O104:H4 str. 2009EL-2050 FKBP-type peptidyl-prolyl cis-trans isomerase YP_006768153.1 494781 D 1134782 CDS YP_006768154.1 410480608 13691028 complement(495420..495638) 1 NC_018650.1 COG2900 Uncharacterized protein conserved in bacteria; phi X174 lysis protein 495638 13691028 O3M_02375 Escherichia coli O104:H4 str. 2009EL-2050 phi X174 lysis protein YP_006768154.1 495420 R 1134782 CDS YP_006768155.1 410480609 13691029 495859..496671 1 NC_018650.1 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; FKBP-type peptidyl-prolyl cis-trans isomerase 496671 13691029 O3M_02380 Escherichia coli O104:H4 str. 2009EL-2050 FKBP-type peptidyl-prolyl cis-trans isomerase YP_006768155.1 495859 D 1134782 CDS YP_006768156.1 410480610 13691030 496838..497560 1 NC_018650.1 COG2964 Uncharacterized protein conserved in bacteria; DNA-binding transcriptional regulator 497560 13691030 O3M_02385 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768156.1 496838 D 1134782 CDS YP_006768157.1 410480611 13691031 497560..497946 1 NC_018650.1 COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction; sulfur transfer complex subunit TusD 497946 13691031 O3M_02390 Escherichia coli O104:H4 str. 2009EL-2050 sulfur transfer complex subunit TusD YP_006768157.1 497560 D 1134782 CDS YP_006768158.1 410480612 13691032 497946..498305 1 NC_018650.1 COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur; sulfur relay protein TusC 498305 13691032 O3M_02395 Escherichia coli O104:H4 str. 2009EL-2050 sulfur relay protein TusC YP_006768158.1 497946 D 1134782 CDS YP_006768159.1 410480613 13691033 498313..498600 1 NC_018650.1 COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur; sulfur transfer complex subunit TusB 498600 13691033 O3M_02400 Escherichia coli O104:H4 str. 2009EL-2050 sulfur transfer complex subunit TusB YP_006768159.1 498313 D 1134782 CDS YP_006768160.1 410480614 13691034 498726..499100 1 NC_018650.1 COG0048 Ribosomal protein S12; 30S ribosomal protein S12 499100 rpsL 13691034 rpsL Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S12 YP_006768160.1 498726 D 1134782 CDS YP_006768161.1 410480615 13691035 499197..499667 1 NC_018650.1 COG0049 Ribosomal protein S7; 30S ribosomal protein S7 499667 13691035 O3M_02410 Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S7 YP_006768161.1 499197 D 1134782 CDS YP_006768162.1 410480616 13691036 499764..501878 1 NC_018650.1 COG0480 Translation elongation factors (GTPases); elongation factor G 501878 13691036 O3M_02415 Escherichia coli O104:H4 str. 2009EL-2050 elongation factor G YP_006768162.1 499764 D 1134782 CDS YP_006768163.1 410480617 13691037 501949..503133 1 NC_018650.1 COG0050 GTPases - translation elongation factors; elongation factor Tu 503133 13691037 O3M_02420 Escherichia coli O104:H4 str. 2009EL-2050 elongation factor Tu YP_006768163.1 501949 D 1134782 CDS YP_006768164.1 410480618 13691038 503316..503510 1 NC_018650.1 COG2906 Bacterioferritin-associated ferredoxin; bacterioferritin-associated ferredoxin 503510 13691038 O3M_02425 Escherichia coli O104:H4 str. 2009EL-2050 bacterioferritin-associated ferredoxin YP_006768164.1 503316 D 1134782 CDS YP_006768165.1 410480619 13691039 503583..504059 1 NC_018650.1 COG2193 Bacterioferritin (cytochrome b1); bacterioferritin 504059 13691039 O3M_02430 Escherichia coli O104:H4 str. 2009EL-2050 bacterioferritin YP_006768165.1 503583 D 1134782 CDS YP_006768166.1 410480620 13691040 complement(504056..504523) 1 NC_018650.1 leader peptidase; methyl transferase (General Secretory Pathway); COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; bifunctional prepilin peptidase HopD 504523 13691040 O3M_02435 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional prepilin peptidase HopD YP_006768166.1 504056 R 1134782 CDS YP_006768167.1 410480621 13691041 504902..505213 1 NC_018650.1 COG0051 Ribosomal protein S10; 30S ribosomal protein S10 505213 rpsJ 13691041 rpsJ Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S10 YP_006768167.1 504902 D 1134782 CDS YP_006768168.1 410480622 13691042 505246..505875 1 NC_018650.1 COG0087 Ribosomal protein L3; 50S ribosomal protein L3 505875 rplC 13691042 rplC Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L3 YP_006768168.1 505246 D 1134782 CDS YP_006768169.1 410480623 13691043 505886..506491 1 NC_018650.1 COG0088 Ribosomal protein L4; 50S ribosomal protein L4 506491 rplD 13691043 rplD Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L4 YP_006768169.1 505886 D 1134782 CDS YP_006768170.1 410480624 13691044 506488..506790 1 NC_018650.1 COG0089 Ribosomal protein L23; 50S ribosomal protein L23 506790 rplW 13691044 rplW Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L23 YP_006768170.1 506488 D 1134782 CDS YP_006768171.1 410480625 13691045 506808..507629 1 NC_018650.1 COG0090 Ribosomal protein L2; 50S ribosomal protein L2 507629 rplB 13691045 rplB Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L2 YP_006768171.1 506808 D 1134782 CDS YP_006768172.1 410480626 13691046 507646..507924 1 NC_018650.1 COG0185 Ribosomal protein S19; 30S ribosomal protein S19 507924 rpsS 13691046 rpsS Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S19 YP_006768172.1 507646 D 1134782 CDS YP_006768173.1 410480627 13691047 507939..508271 1 NC_018650.1 COG0091 Ribosomal protein L22; 50S ribosomal protein L22 508271 rplV 13691047 rplV Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L22 YP_006768173.1 507939 D 1134782 CDS YP_006768174.1 410480628 13691048 508289..508990 1 NC_018650.1 COG0092 Ribosomal protein S3; 30S ribosomal protein S3 508990 rpsC 13691048 rpsC Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S3 YP_006768174.1 508289 D 1134782 CDS YP_006768175.1 410480629 13691049 509003..509413 1 NC_018650.1 COG0197 Ribosomal protein L16/L10E; 50S ribosomal protein L16 509413 rplP 13691049 rplP Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L16 YP_006768175.1 509003 D 1134782 CDS YP_006768176.1 410480630 13691050 509413..509604 1 NC_018650.1 COG0255 Ribosomal protein L29; 50S ribosomal protein L29 509604 13691050 O3M_02485 Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L29 YP_006768176.1 509413 D 1134782 CDS YP_006768177.1 410480631 13691051 509604..509858 1 NC_018650.1 COG0186 Ribosomal protein S17; 30S ribosomal protein S17 509858 rpsQ 13691051 rpsQ Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S17 YP_006768177.1 509604 D 1134782 CDS YP_006768178.1 410480632 13691052 510023..510394 1 NC_018650.1 COG0093 Ribosomal protein L14; 50S ribosomal protein L14 510394 rplN 13691052 rplN Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L14 YP_006768178.1 510023 D 1134782 CDS YP_006768179.1 410480633 13691053 510405..510719 1 NC_018650.1 COG0198 Ribosomal protein L24; 50S ribosomal protein L24 510719 rplX 13691053 rplX Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L24 YP_006768179.1 510405 D 1134782 CDS YP_006768180.1 410480634 13691054 510734..511273 1 NC_018650.1 COG0094 Ribosomal protein L5; 50S ribosomal protein L5 511273 rplE 13691054 rplE Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L5 YP_006768180.1 510734 D 1134782 CDS YP_006768181.1 410480635 13691055 511288..511593 1 NC_018650.1 COG0199 Ribosomal protein S14; 30S ribosomal protein S14 511593 rpsN 13691055 rpsN Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S14 YP_006768181.1 511288 D 1134782 CDS YP_006768182.1 410480636 13691056 511627..512019 1 NC_018650.1 COG0096 Ribosomal protein S8; 30S ribosomal protein S8 512019 rpsH 13691056 rpsH Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S8 YP_006768182.1 511627 D 1134782 CDS YP_006768183.1 410480637 13691057 512032..512565 1 NC_018650.1 COG0097 Ribosomal protein L6P/L9E; 50S ribosomal protein L6 512565 rplF 13691057 rplF Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L6 YP_006768183.1 512032 D 1134782 CDS YP_006768184.1 410480638 13691058 512575..512928 1 NC_018650.1 COG0256 Ribosomal protein L18; 50S ribosomal protein L18 512928 rplR 13691058 rplR Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L18 YP_006768184.1 512575 D 1134782 CDS YP_006768185.1 410480639 13691059 512943..513446 1 NC_018650.1 COG0098 Ribosomal protein S5; 30S ribosomal protein S5 513446 rpsE 13691059 rpsE Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S5 YP_006768185.1 512943 D 1134782 CDS YP_006768186.1 410480640 13691060 513450..513629 1 NC_018650.1 COG1841 Ribosomal protein L30/L7E; 50S ribosomal protein L30 513629 rpmD 13691060 rpmD Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L30 YP_006768186.1 513450 D 1134782 CDS YP_006768187.1 410480641 13691061 513633..514067 1 NC_018650.1 COG0200 Ribosomal protein L15; 50S ribosomal protein L15 514067 rplO 13691061 rplO Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L15 YP_006768187.1 513633 D 1134782 CDS YP_006768188.1 410480642 13691062 514075..515406 1 NC_018650.1 COG0201 Preprotein translocase subunit SecY; preprotein translocase subunit SecY 515406 secY 13691062 secY Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit SecY YP_006768188.1 514075 D 1134782 CDS YP_006768189.1 410480643 13691063 515438..515554 1 NC_018650.1 COG0257 Ribosomal protein L36; 50S ribosomal protein L36 515554 rpmJ 13691063 rpmJ Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L36 YP_006768189.1 515438 D 1134782 CDS YP_006768190.1 410480644 13691064 515701..516057 1 NC_018650.1 COG0099 Ribosomal protein S13; 30S ribosomal protein S13 516057 rpsM 13691064 rpsM Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S13 YP_006768190.1 515701 D 1134782 CDS YP_006768191.1 410480645 13691065 516074..516463 1 NC_018650.1 COG0100 Ribosomal protein S11; 30S ribosomal protein S11 516463 13691065 O3M_02560 Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S11 YP_006768191.1 516074 D 1134782 CDS YP_006768192.1 410480646 13691066 516497..517117 1 NC_018650.1 COG0522 Ribosomal protein S4 and related proteins; 30S ribosomal protein S4 517117 rpsD 13691066 rpsD Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S4 YP_006768192.1 516497 D 1134782 CDS YP_006768193.1 410480647 13691067 517143..518132 1 NC_018650.1 COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-directed RNA polymerase subunit alpha 518132 13691067 O3M_02570 Escherichia coli O104:H4 str. 2009EL-2050 DNA-directed RNA polymerase subunit alpha YP_006768193.1 517143 D 1134782 CDS YP_006768194.1 410480648 13691068 518173..518556 1 NC_018650.1 COG0203 Ribosomal protein L17; 50S ribosomal protein L17 518556 rplQ 13691068 rplQ Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L17 YP_006768194.1 518173 D 1134782 CDS YP_006768195.1 410480649 13691069 518663..519031 1 NC_018650.1 hypothetical protein 519031 13691069 O3M_02580 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768195.1 518663 D 1134782 CDS YP_006768196.1 410480650 13691070 519042..519467 1 NC_018650.1 COG0789 Predicted transcriptional regulators; zinc-responsive transcriptional regulator 519467 zntR 13691070 zntR Escherichia coli O104:H4 str. 2009EL-2050 zinc-responsive transcriptional regulator YP_006768196.1 519042 D 1134782 CDS YP_006768197.1 410480651 13691071 519523..519741 1 NC_018650.1 COG3036 Uncharacterized protein conserved in bacteria; hypothetical protein 519741 13691071 O3M_02590 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768197.1 519523 D 1134782 CDS YP_006768198.1 410480652 13691072 complement(519738..520148) 1 NC_018650.1 COG1970 Large-conductance mechanosensitive channel; large conductance mechanosensitive channel protein 520148 mscL 13691072 mscL Escherichia coli O104:H4 str. 2009EL-2050 large conductance mechanosensitive channel protein YP_006768198.1 519738 R 1134782 CDS YP_006768199.1 410480653 13691073 complement(520278..521654) 1 NC_018650.1 COG0569 K+ transport systems, NAD-binding component; potassium transporter peripheral membrane protein 521654 trkA 13691073 trkA Escherichia coli O104:H4 str. 2009EL-2050 potassium transporter peripheral membrane protein YP_006768199.1 520278 R 1134782 CDS YP_006768200.1 410480654 13691074 complement(521676..522965) 1 NC_018650.1 COG0144 tRNA and rRNA cytosine-C5-methylases; 16S rRNA methyltransferase B 522965 13691074 O3M_02605 Escherichia coli O104:H4 str. 2009EL-2050 16S rRNA methyltransferase B YP_006768200.1 521676 R 1134782 CDS YP_006768201.1 410480655 13691075 complement(523011..523958) 1 NC_018650.1 COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 523958 fmt 13691075 fmt Escherichia coli O104:H4 str. 2009EL-2050 methionyl-tRNA formyltransferase YP_006768201.1 523011 R 1134782 CDS YP_006768202.1 410480656 13691076 complement(523973..524482) 1 NC_018650.1 COG0242 N-formylmethionyl-tRNA deformylase; peptide deformylase 524482 def 13691076 def Escherichia coli O104:H4 str. 2009EL-2050 peptide deformylase YP_006768202.1 523973 R 1134782 CDS YP_006768203.1 410480657 13691077 524612..525736 1 NC_018650.1 COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 525736 13691077 O3M_02620 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768203.1 524612 D 1134782 CDS YP_006768204.1 410480658 13691078 525708..526181 1 NC_018650.1 COG2922 Uncharacterized protein conserved in bacteria; hypothetical protein 526181 13691078 O3M_02625 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768204.1 525708 D 1134782 CDS YP_006768205.1 410480659 13691079 526210..526752 1 NC_018650.1 COG0551 Zn-finger domain associated with topoisomerase type I; DNA topoisomerase 526752 13691079 O3M_02630 Escherichia coli O104:H4 str. 2009EL-2050 DNA topoisomerase YP_006768205.1 526210 D 1134782 CDS YP_006768206.1 410480660 13691080 526757..527329 1 NC_018650.1 COG0009 Putative translation factor (SUA5); tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein 527329 13691080 O3M_02635 Escherichia coli O104:H4 str. 2009EL-2050 tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein YP_006768206.1 526757 D 1134782 CDS YP_006768207.1 410480661 13691081 527334..528152 1 NC_018650.1 COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 528152 aroE 13691081 aroE Escherichia coli O104:H4 str. 2009EL-2050 shikimate 5-dehydrogenase YP_006768207.1 527334 D 1134782 CDS YP_006768208.1 410480662 13691082 528149..528406 1 NC_018650.1 hypothetical protein 528406 13691082 O3M_02645 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768208.1 528149 D 1134782 CDS YP_006768209.1 410480663 13691083 complement(528382..528936) 1 NC_018650.1 COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; hypothetical protein 528936 13691083 O3M_02650 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768209.1 528382 R 1134782 CDS YP_006768210.1 410480664 13691091 complement(534988..535746) 1 NC_018650.1 COG1126 ABC-type polar amino acid transport system, ATPase component; phosphate ABC transporter ATP-binding protein 535746 13691091 O3M_02655 Escherichia coli O104:H4 str. 2009EL-2050 phosphate ABC transporter ATP-binding protein YP_006768210.1 534988 R 1134782 CDS YP_006768211.1 410480665 13691092 complement(535754..536857) 1 NC_018650.1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 536857 13691092 O3M_02660 Escherichia coli O104:H4 str. 2009EL-2050 amino acid ABC transporter permease YP_006768211.1 535754 R 1134782 CDS YP_006768212.1 410480666 13691093 complement(536867..538048) 1 NC_018650.1 COG4597 ABC-type amino acid transport system, permease component; transport system permease 538048 13691093 O3M_02665 Escherichia coli O104:H4 str. 2009EL-2050 transport system permease YP_006768212.1 536867 R 1134782 CDS YP_006768213.1 410480667 13691094 complement(538116..539141) 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein 539141 13691094 O3M_02670 Escherichia coli O104:H4 str. 2009EL-2050 amino acid ABC transporter substrate-binding protein YP_006768213.1 538116 R 1134782 CDS YP_006768214.1 410480668 13691095 complement(539572..539793) 1 NC_018650.1 hypothetical protein 539793 13691095 O3M_02675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768214.1 539572 R 1134782 CDS YP_006768215.1 410480669 13691096 complement(540046..543150) 1 NC_018650.1 COG0841 Cation/multidrug efflux pump; acriflavine resistance protein 543150 13691096 O3M_02680 Escherichia coli O104:H4 str. 2009EL-2050 acriflavine resistance protein YP_006768215.1 540046 R 1134782 CDS YP_006768216.1 410480670 13691097 complement(543162..544319) 1 NC_018650.1 COG0845 Membrane-fusion protein; hypothetical protein 544319 13691097 O3M_02685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768216.1 543162 R 1134782 CDS YP_006768217.1 410480671 13691098 544718..545380 1 NC_018650.1 COG1309 Transcriptional regulator; DNA-binding transcriptional regulator EnvR 545380 13691098 O3M_02690 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator EnvR YP_006768217.1 544718 D 1134782 CDS YP_006768218.1 410480672 13691099 complement(545383..545562) 1 NC_018650.1 hypothetical protein 545562 13691099 O3M_02695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768218.1 545383 R 1134782 CDS YP_006768219.1 410480673 13691100 complement(545646..546530) 1 NC_018650.1 COG0863 DNA modification methylase; methyltransferase 546530 13691100 O3M_02700 Escherichia coli O104:H4 str. 2009EL-2050 methyltransferase YP_006768219.1 545646 R 1134782 CDS YP_006768220.1 410480674 13691101 complement(546616..546912) 1 NC_018650.1 COG2901 Factor for inversion stimulation Fis, transcriptional activator; global DNA-binding transcriptional dual regulator Fis 546912 fis 13691101 fis Escherichia coli O104:H4 str. 2009EL-2050 global DNA-binding transcriptional dual regulator Fis YP_006768220.1 546616 R 1134782 CDS YP_006768221.1 410480675 13691102 complement(546938..547903) 1 NC_018650.1 COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase B 547903 13691102 O3M_02710 Escherichia coli O104:H4 str. 2009EL-2050 tRNA-dihydrouridine synthase B YP_006768221.1 546938 R 1134782 CDS YP_006768222.1 410480676 13691103 complement(548232..549113) 1 NC_018650.1 COG2264 Ribosomal protein L11 methylase; 50S ribosomal protein L11 methyltransferase 549113 prmA 13691103 prmA Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L11 methyltransferase YP_006768222.1 548232 R 1134782 CDS YP_006768223.1 410480677 13691104 complement(549125..550576) 1 NC_018650.1 COG4145 Na+/panthothenate symporter; sodium/panthothenate symporter 550576 panF 13691104 panF Escherichia coli O104:H4 str. 2009EL-2050 sodium/panthothenate symporter YP_006768223.1 549125 R 1134782 CDS YP_006768224.1 410480678 13691105 complement(550566..550808) 1 NC_018650.1 COG3924 Predicted membrane protein; hypothetical protein 550808 13691105 O3M_02725 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768224.1 550566 R 1134782 CDS YP_006768225.1 410480679 13691106 complement(550917..552266) 1 NC_018650.1 COG0439 Biotin carboxylase; acetyl-CoA carboxylase biotin carboxylase subunit 552266 13691106 O3M_02730 Escherichia coli O104:H4 str. 2009EL-2050 acetyl-CoA carboxylase biotin carboxylase subunit YP_006768225.1 550917 R 1134782 CDS YP_006768226.1 410480680 13691107 complement(552277..552747) 1 NC_018650.1 COG0511 Biotin carboxyl carrier protein; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 552747 13691107 O3M_02735 Escherichia coli O104:H4 str. 2009EL-2050 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_006768226.1 552277 R 1134782 CDS YP_006768227.1 410480681 13691108 complement(553152..553316) 1 NC_018650.1 COG2717 Predicted membrane protein; hypothetical protein 553316 13691108 O3M_02740 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768227.1 553152 R 1134782 CDS YP_006768228.1 410480682 13691109 complement(553725..554699) 1 NC_018650.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; quinone oxidoreductase 554699 13691109 O3M_02745 Escherichia coli O104:H4 str. 2009EL-2050 quinone oxidoreductase YP_006768228.1 553725 R 1134782 CDS YP_006768229.1 410480683 13691110 554851..556791 1 NC_018650.1 COG2199 FOG: GGDEF domain; regulatory protein CsrD 556791 13691110 O3M_02750 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein CsrD YP_006768229.1 554851 D 1134782 CDS YP_006768230.1 410480684 13691111 557096..558139 1 NC_018650.1 COG1077 Actin-like ATPase involved in cell morphogenesis; rod shape-determining protein MreB 558139 13691111 O3M_02755 Escherichia coli O104:H4 str. 2009EL-2050 rod shape-determining protein MreB YP_006768230.1 557096 D 1134782 CDS YP_006768231.1 410480685 13691112 558205..559308 1 NC_018650.1 COG1792 Cell shape-determining protein; rod shape-determining protein MreC 559308 13691112 O3M_02760 Escherichia coli O104:H4 str. 2009EL-2050 rod shape-determining protein MreC YP_006768231.1 558205 D 1134782 CDS YP_006768232.1 410480686 13691113 559193..559324 1 NC_018650.1 hypothetical protein 559324 13691113 O3M_02765 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768232.1 559193 D 1134782 CDS YP_006768233.1 410480687 13691114 559308..559796 1 NC_018650.1 COG2891 Cell shape-determining protein; rod shape-determining protein MreD 559796 13691114 O3M_02770 Escherichia coli O104:H4 str. 2009EL-2050 rod shape-determining protein MreD YP_006768233.1 559308 D 1134782 CDS YP_006768234.1 410480688 13691115 559805..560398 1 NC_018650.1 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; maf-like protein 560398 13691115 O3M_02775 Escherichia coli O104:H4 str. 2009EL-2050 maf-like protein YP_006768234.1 559805 D 1134782 CDS YP_006768235.1 410480689 13691116 560388..561857 1 NC_018650.1 COG1530 Ribonucleases G and E; ribonuclease G 561857 13691116 O3M_02780 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease G YP_006768235.1 560388 D 1134782 CDS YP_006768236.1 410480690 13691117 561925..565725 1 NC_018650.1 COG3164 Predicted membrane protein; hypothetical protein 565725 13691117 O3M_02785 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768236.1 561925 D 1134782 CDS YP_006768237.1 410480691 13691118 565881..567326 1 NC_018650.1 COG0312 Predicted Zn-dependent proteases and their inactivated homologs; protease TldD 567326 tldD 13691118 tldD Escherichia coli O104:H4 str. 2009EL-2050 protease TldD YP_006768237.1 565881 D 1134782 CDS YP_006768238.1 410480692 13691119 complement(567454..568383) 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional regulator 568383 13691119 O3M_02795 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768238.1 567454 R 1134782 CDS YP_006768239.1 410480693 13691120 568566..568769 1 NC_018650.1 efflux system membrane protein 568769 13691120 O3M_02800 Escherichia coli O104:H4 str. 2009EL-2050 efflux system membrane protein YP_006768239.1 568566 D 1134782 CDS YP_006768240.1 410480694 13691121 568777..569709 1 NC_018650.1 COG1566 Multidrug resistance efflux pump; p-hydroxybenzoic acid efflux subunit AaeA 569709 13691121 O3M_02805 Escherichia coli O104:H4 str. 2009EL-2050 p-hydroxybenzoic acid efflux subunit AaeA YP_006768240.1 568777 D 1134782 CDS YP_006768241.1 410480695 13691122 569715..571682 1 NC_018650.1 COG1289 Predicted membrane protein; p-hydroxybenzoic acid efflux subunit AaeB 571682 13691122 O3M_02810 Escherichia coli O104:H4 str. 2009EL-2050 p-hydroxybenzoic acid efflux subunit AaeB YP_006768241.1 569715 D 1134782 CDS YP_006768242.1 410480696 13691123 571774..572046 1 NC_018650.1 COG2732 Barstar, RNAse (barnase) inhibitor; barnase inhibitor 572046 13691123 O3M_02815 Escherichia coli O104:H4 str. 2009EL-2050 barnase inhibitor YP_006768242.1 571774 D 1134782 CDS YP_006768243.1 410480697 13691124 complement(572102..572365) 1 NC_018650.1 hypothetical protein 572365 13691124 O3M_02820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768243.1 572102 R 1134782 CDS YP_006768244.1 410480698 13691125 complement(572730..573200) 1 NC_018650.1 COG1438 Arginine repressor; arginine repressor 573200 13691125 O3M_02825 Escherichia coli O104:H4 str. 2009EL-2050 arginine repressor YP_006768244.1 572730 R 1134782 CDS YP_006768245.1 410480699 13691126 573635..574573 1 NC_018650.1 COG0039 Malate/lactate dehydrogenases; malate dehydrogenase 574573 13691126 O3M_02830 Escherichia coli O104:H4 str. 2009EL-2050 malate dehydrogenase YP_006768245.1 573635 D 1134782 CDS YP_006768246.1 410480700 13691127 complement(574636..575703) 1 NC_018650.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease 575703 13691127 O3M_02835 Escherichia coli O104:H4 str. 2009EL-2050 serine endoprotease YP_006768246.1 574636 R 1134782 CDS YP_006768247.1 410480701 13691128 complement(575793..577160) 1 NC_018650.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease 577160 13691128 O3M_02840 Escherichia coli O104:H4 str. 2009EL-2050 serine endoprotease YP_006768247.1 575793 R 1134782 CDS YP_006768248.1 410480702 13691129 complement(577314..577712) 1 NC_018650.1 COG3105 Uncharacterized protein conserved in bacteria; hypothetical protein 577712 13691129 O3M_02845 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768248.1 577314 R 1134782 CDS YP_006768249.1 410480703 13691130 577906..579033 1 NC_018650.1 COG1485 Predicted ATPase; nucleoside triphosphate hydrolase domain-containing protein 579033 13691130 O3M_02850 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside triphosphate hydrolase domain-containing protein YP_006768249.1 577906 D 1134782 CDS YP_006768250.1 410480704 13691131 579252..579680 1 NC_018650.1 COG0102 Ribosomal protein L13; 50S ribosomal protein L13 579680 rplM 13691131 rplM Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L13 YP_006768250.1 579252 D 1134782 CDS YP_006768251.1 410480705 13691132 579696..580088 1 NC_018650.1 COG0103 Ribosomal protein S9; 30S ribosomal protein S9 580088 rpsI 13691132 rpsI Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S9 YP_006768251.1 579696 D 1134782 CDS YP_006768252.1 410480706 13691133 580483..581121 1 NC_018650.1 COG0625 Glutathione S-transferase; stringent starvation protein A 581121 sspA 13691133 sspA Escherichia coli O104:H4 str. 2009EL-2050 stringent starvation protein A YP_006768252.1 580483 D 1134782 CDS YP_006768253.1 410480707 13691134 581127..581624 1 NC_018650.1 COG2969 Stringent starvation protein B; ClpXP protease specificity-enhancing factor 581624 13691134 O3M_02870 Escherichia coli O104:H4 str. 2009EL-2050 ClpXP protease specificity-enhancing factor YP_006768253.1 581127 D 1134782 CDS YP_006768254.1 410480708 13691135 complement(581667..583034) 1 NC_018650.1 COG3069 C4-dicarboxylate transporter; cryptic C4-dicarboxylate transporter DcuD 583034 13691135 O3M_02875 Escherichia coli O104:H4 str. 2009EL-2050 cryptic C4-dicarboxylate transporter DcuD YP_006768254.1 581667 R 1134782 CDS YP_006768255.1 410480709 13691136 583414..584205 1 NC_018650.1 COG2186 Transcriptional regulators; transcriptional regulator NanR 584205 13691136 O3M_02880 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator NanR YP_006768255.1 583414 D 1134782 CDS YP_006768256.1 410480710 13691137 584327..585220 1 NC_018650.1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; N-acetylneuraminate lyase 585220 13691137 O3M_02885 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylneuraminate lyase YP_006768256.1 584327 D 1134782 CDS YP_006768257.1 410480711 13691138 585329..586819 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; sialic acid transporter 586819 13691138 O3M_02890 Escherichia coli O104:H4 str. 2009EL-2050 sialic acid transporter YP_006768257.1 585329 D 1134782 CDS YP_006768258.1 410480712 13691139 586867..587556 1 NC_018650.1 COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; N-acetylmannosamine-6-phosphate 2-epimerase 587556 13691139 O3M_02895 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmannosamine-6-phosphate 2-epimerase YP_006768258.1 586867 D 1134782 CDS YP_006768259.1 410480713 13691140 587553..588428 1 NC_018650.1 COG1940 Transcriptional regulator/sugar kinase; N-acetylmannosamine kinase 588428 13691140 O3M_02900 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmannosamine kinase YP_006768259.1 587553 D 1134782 CDS YP_006768260.1 410480714 13691141 588425..588889 1 NC_018650.1 COG2731 Beta-galactosidase, beta subunit; hypothetical protein 588889 13691141 O3M_02905 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768260.1 588425 D 1134782 CDS YP_006768261.1 410480715 13691142 complement(588965..589270) 1 NC_018650.1 IS600 orf 589270 13691142 O3M_02910 Escherichia coli O104:H4 str. 2009EL-2050 IS600 orf YP_006768261.1 588965 R 1134782 CDS YP_006768262.1 410480716 13691143 complement(589287..589766) 1 NC_018650.1 COG4804 Uncharacterized conserved protein; hypothetical protein 589766 13691143 O3M_02915 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768262.1 589287 R 1134782 CDS YP_006768263.1 410480717 13691144 complement(589950..591368) 1 NC_018650.1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; glutamate synthase subunit beta 591368 gltD 13691144 gltD Escherichia coli O104:H4 str. 2009EL-2050 glutamate synthase subunit beta YP_006768263.1 589950 R 1134782 CDS YP_006768264.1 410480718 13691145 complement(591381..595841) 1 NC_018650.1 COG0067 Glutamate synthase domain 1; glutamate synthase subunit alpha 595841 gltB 13691145 gltB Escherichia coli O104:H4 str. 2009EL-2050 glutamate synthase subunit alpha YP_006768264.1 591381 R 1134782 CDS YP_006768265.1 410480719 13691146 596516..597445 1 NC_018650.1 COG1242 Predicted Fe-S oxidoreductase; Fe-S oxidoreductase 597445 13691146 O3M_02930 Escherichia coli O104:H4 str. 2009EL-2050 Fe-S oxidoreductase YP_006768265.1 596516 D 1134782 CDS YP_006768266.1 410480720 13691147 597541..599877 1 NC_018650.1 COG0642 Signal transduction histidine kinase; aerobic respiration control sensor protein ArcB 599877 13691147 O3M_02935 Escherichia coli O104:H4 str. 2009EL-2050 aerobic respiration control sensor protein ArcB YP_006768266.1 597541 D 1134782 CDS YP_006768267.1 410480721 13691148 600107..600760 1 NC_018650.1 COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis; isoprenoid biosynthesis protein 600760 13691148 O3M_02940 Escherichia coli O104:H4 str. 2009EL-2050 isoprenoid biosynthesis protein YP_006768267.1 600107 D 1134782 CDS YP_006768268.1 410480722 13691149 600757..601485 1 NC_018650.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); monofunctional biosynthetic peptidoglycan transglycosylase 601485 mtgA 13691149 mtgA Escherichia coli O104:H4 str. 2009EL-2050 monofunctional biosynthetic peptidoglycan transglycosylase YP_006768268.1 600757 D 1134782 CDS YP_006768269.1 410480723 13691150 complement(601482..602114) 1 NC_018650.1 hypothetical protein 602114 13691150 O3M_02950 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768269.1 601482 R 1134782 CDS YP_006768270.1 410480724 13691151 complement(602327..602599) 1 NC_018650.1 COG1925 Phosphotransferase system, HPr-related proteins; PTS system phosphohistidinoprotein-hexose phosphotransferase Npr 602599 13691151 O3M_02955 Escherichia coli O104:H4 str. 2009EL-2050 PTS system phosphohistidinoprotein-hexose phosphotransferase Npr YP_006768270.1 602327 R 1134782 CDS YP_006768271.1 410480725 13691152 complement(602596..603450) 1 NC_018650.1 COG1660 Predicted P-loop-containing kinase; glmZ(sRNA)-inactivating NTPase 603450 13691152 O3M_02960 Escherichia coli O104:H4 str. 2009EL-2050 glmZ(sRNA)-inactivating NTPase YP_006768271.1 602596 R 1134782 CDS YP_006768272.1 410480726 13691153 complement(603496..603987) 1 NC_018650.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system sugar transporter subunit IIA 603987 13691153 O3M_02965 Escherichia coli O104:H4 str. 2009EL-2050 PTS system sugar transporter subunit IIA YP_006768272.1 603496 R 1134782 CDS YP_006768273.1 410480727 13691154 complement(604105..604392) 1 NC_018650.1 COG1544 Ribosome-associated protein Y (PSrp-1); ribosome hibernation promoting factor HPF 604392 13691154 O3M_02970 Escherichia coli O104:H4 str. 2009EL-2050 ribosome hibernation promoting factor HPF YP_006768273.1 604105 R 1134782 CDS YP_006768274.1 410480728 13691155 complement(604415..605848) 1 NC_018650.1 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; RNA polymerase factor sigma-54 605848 13691155 O3M_02975 Escherichia coli O104:H4 str. 2009EL-2050 RNA polymerase factor sigma-54 YP_006768274.1 604415 R 1134782 CDS YP_006768275.1 410480729 13691156 complement(605896..606621) 1 NC_018650.1 COG1137 ABC-type (unclassified) transport system, ATPase component; lipopolysaccharide ABC transporter ATP-binding protein 606621 13691156 O3M_02980 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide ABC transporter ATP-binding protein YP_006768275.1 605896 R 1134782 CDS YP_006768276.1 410480730 13691157 complement(606628..607185) 1 NC_018650.1 COG1934 Uncharacterized protein conserved in bacteria; lipopolysaccharide transport periplasmic protein LptA 607185 13691157 O3M_02985 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide transport periplasmic protein LptA YP_006768276.1 606628 R 1134782 CDS YP_006768277.1 410480731 13691158 complement(607154..607729) 1 NC_018650.1 COG3117 Uncharacterized protein conserved in bacteria; lipopolysaccharide exporter periplasmic protein 607729 13691158 O3M_02990 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide exporter periplasmic protein YP_006768277.1 607154 R 1134782 CDS YP_006768278.1 410480732 13691159 complement(607726..608292) 1 NC_018650.1 COG1778 Low specificity phosphatase (HAD superfamily); 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 608292 13691159 O3M_02995 Escherichia coli O104:H4 str. 2009EL-2050 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_006768278.1 607726 R 1134782 CDS YP_006768279.1 410480733 13691160 complement(608313..609299) 1 NC_018650.1 COG0794 Predicted sugar phosphate isomerase involved in capsule formation; D-arabinose 5-phosphate isomerase 609299 13691160 O3M_03000 Escherichia coli O104:H4 str. 2009EL-2050 D-arabinose 5-phosphate isomerase YP_006768279.1 608313 R 1134782 CDS YP_006768280.1 410480734 13691161 complement(609313..610290) 1 NC_018650.1 COG0530 Ca2+/Na+ antiporter; calcium/sodium:proton antiporter 610290 13691161 O3M_03005 Escherichia coli O104:H4 str. 2009EL-2050 calcium/sodium:proton antiporter YP_006768280.1 609313 R 1134782 CDS YP_006768281.1 410480735 13691162 610500..611309 1 NC_018650.1 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; ABC transporter ATP-binding protein 611309 13691162 O3M_03010 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006768281.1 610500 D 1134782 CDS YP_006768282.1 410480736 13691163 611317..612099 1 NC_018650.1 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; toluene ABC transporter permease 612099 13691163 O3M_03015 Escherichia coli O104:H4 str. 2009EL-2050 toluene ABC transporter permease YP_006768282.1 611317 D 1134782 CDS YP_006768283.1 410480737 13691164 612104..612655 1 NC_018650.1 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; hypothetical protein 612655 13691164 O3M_03020 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768283.1 612104 D 1134782 CDS YP_006768284.1 410480738 13691165 612674..613309 1 NC_018650.1 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component; ABC transporter substrate-binding protein MlaC 613309 13691165 O3M_03025 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter substrate-binding protein MlaC YP_006768284.1 612674 D 1134782 CDS YP_006768285.1 410480739 13691166 613309..613602 1 NC_018650.1 COG3113 Predicted NTP binding protein (contains STAS domain); hypothetical protein 613602 13691166 O3M_03030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768285.1 613309 D 1134782 CDS YP_006768286.1 410480740 13691167 613762..614016 1 NC_018650.1 COG5007 Predicted transcriptional regulator, BolA superfamily; DNA-binding transcriptional regulator 614016 13691167 O3M_03035 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768286.1 613762 D 1134782 CDS YP_006768287.1 410480741 13691168 614071..615330 1 NC_018650.1 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 615330 13691168 O3M_03040 Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_006768287.1 614071 D 1134782 CDS YP_006768288.1 410480742 13691169 complement(615378..615656) 1 NC_018650.1 COG3423 Predicted transcriptional regulator; DNA-binding transcriptional regulator Nlp 615656 13691169 O3M_03045 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator Nlp YP_006768288.1 615378 R 1134782 CDS YP_006768289.1 410480743 13691170 complement(615884..616855) 1 NC_018650.1 COG0142 Geranylgeranyl pyrophosphate synthase; octaprenyl diphosphate synthase 616855 13691170 O3M_03050 Escherichia coli O104:H4 str. 2009EL-2050 octaprenyl diphosphate synthase YP_006768289.1 615884 R 1134782 CDS YP_006768290.1 410480744 13691171 617114..617425 1 NC_018650.1 COG0261 Ribosomal protein L21; 50S ribosomal protein L21 617425 rplU 13691171 rplU Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L21 YP_006768290.1 617114 D 1134782 CDS YP_006768291.1 410480745 13691172 617446..617703 1 NC_018650.1 COG0211 Ribosomal protein L27; 50S ribosomal protein L27 617703 rpmA 13691172 rpmA Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L27 YP_006768291.1 617446 D 1134782 CDS YP_006768292.1 410480746 13691173 617830..618795 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 618795 13691173 O3M_03065 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768292.1 617830 D 1134782 CDS YP_006768293.1 410480747 13691174 618811..619983 1 NC_018650.1 COG0536 Predicted GTPase; GTPase CgtA 619983 obgE 13691174 obgE Escherichia coli O104:H4 str. 2009EL-2050 GTPase CgtA YP_006768293.1 618811 D 1134782 CDS YP_006768294.1 410480748 13691175 complement(620023..621456) 1 NC_018650.1 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); D-alanyl-D-alanine carboxypeptidase 621456 13691175 O3M_03075 Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-D-alanine carboxypeptidase YP_006768294.1 620023 R 1134782 CDS YP_006768295.1 410480749 13691176 621704..622180 1 NC_018650.1 COG0782 Transcription elongation factor; transcription elongation factor GreA 622180 greA 13691176 greA Escherichia coli O104:H4 str. 2009EL-2050 transcription elongation factor GreA YP_006768295.1 621704 D 1134782 CDS YP_006768296.1 410480750 13691177 complement(622336..622629) 1 NC_018650.1 COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; RNA-binding protein YhbY 622629 13691177 O3M_03085 Escherichia coli O104:H4 str. 2009EL-2050 RNA-binding protein YhbY YP_006768296.1 622336 R 1134782 CDS YP_006768297.1 410480751 13691178 622755..623384 1 NC_018650.1 COG0293 23S rRNA methylase; 23S rRNA methyltransferase J 623384 rrmJ 13691178 rrmJ Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA methyltransferase J YP_006768297.1 622755 D 1134782 CDS YP_006768298.1 410480752 13691179 623484..625418 1 NC_018650.1 COG0465 ATP-dependent Zn proteases; ATP-dependent metalloprotease 625418 hflB 13691179 hflB Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent metalloprotease YP_006768298.1 623484 D 1134782 CDS YP_006768299.1 410480753 13691180 625508..626356 1 NC_018650.1 COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase 626356 folP 13691180 folP Escherichia coli O104:H4 str. 2009EL-2050 dihydropteroate synthase YP_006768299.1 625508 D 1134782 CDS YP_006768300.1 410480754 13691181 626349..627686 1 NC_018650.1 COG1109 Phosphomannomutase; phosphoglucosamine mutase 627686 glmM 13691181 glmM Escherichia coli O104:H4 str. 2009EL-2050 phosphoglucosamine mutase YP_006768300.1 626349 D 1134782 CDS YP_006768301.1 410480755 13691182 627914..628246 1 NC_018650.1 COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 628246 secG 13691182 secG Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit SecG YP_006768301.1 627914 D 1134782 CDS YP_006768302.1 410480756 13691184 628804..630429 1 NC_018650.1 COG2194 Predicted membrane-associated, metal-dependent hydrolase; hydrolase, inner membrane 630429 13691184 O3M_03115 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase, inner membrane YP_006768302.1 628804 D 1134782 CDS YP_006768303.1 410480757 13691185 complement(630437..631780) 1 NC_018650.1 COG0137 Argininosuccinate synthase; argininosuccinate synthase 631780 13691185 O3M_03120 Escherichia coli O104:H4 str. 2009EL-2050 argininosuccinate synthase YP_006768303.1 630437 R 1134782 CDS YP_006768304.1 410480758 13691187 632411..632863 1 NC_018650.1 COG0779 Uncharacterized protein conserved in bacteria; ribosome maturation protein RimP 632863 13691187 O3M_03125 Escherichia coli O104:H4 str. 2009EL-2050 ribosome maturation protein RimP YP_006768304.1 632411 D 1134782 CDS YP_006768305.1 410480759 13691188 632891..634378 1 NC_018650.1 COG0195 Transcription elongation factor; transcription elongation factor NusA 634378 nusA 13691188 nusA Escherichia coli O104:H4 str. 2009EL-2050 transcription elongation factor NusA YP_006768305.1 632891 D 1134782 CDS YP_006768306.1 410480760 13691189 634403..637075 1 NC_018650.1 COG0532 Translation initiation factor 2 (IF-2; GTPase); translation initiation factor IF-2 637075 infB 13691189 infB Escherichia coli O104:H4 str. 2009EL-2050 translation initiation factor IF-2 YP_006768306.1 634403 D 1134782 CDS YP_006768307.1 410480761 13691190 637239..637640 1 NC_018650.1 COG0858 Ribosome-binding factor A; ribosome-binding factor A 637640 rbfA 13691190 rbfA Escherichia coli O104:H4 str. 2009EL-2050 ribosome-binding factor A YP_006768307.1 637239 D 1134782 CDS YP_006768308.1 410480762 13691191 637640..638584 1 NC_018650.1 COG0130 Pseudouridine synthase; tRNA pseudouridine synthase B 638584 truB 13691191 truB Escherichia coli O104:H4 str. 2009EL-2050 tRNA pseudouridine synthase B YP_006768308.1 637640 D 1134782 CDS YP_006768309.1 410480763 13691192 638733..639002 1 NC_018650.1 COG0184 Ribosomal protein S15P/S13E; 30S ribosomal protein S15 639002 rpsO 13691192 rpsO Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S15 YP_006768309.1 638733 D 1134782 CDS YP_006768310.1 410480764 13691193 639249..641384 1 NC_018650.1 COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 641384 13691193 O3M_03155 Escherichia coli O104:H4 str. 2009EL-2050 polynucleotide phosphorylase/polyadenylase YP_006768310.1 639249 D 1134782 CDS YP_006768311.1 410480765 13691194 641493..642377 1 NC_018650.1 COG4785 Lipoprotein NlpI, contains TPR repeats; lipoprotein NlpI 642377 13691194 O3M_03160 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein NlpI YP_006768311.1 641493 D 1134782 CDS YP_006768312.1 410480766 13691195 642557..644446 1 NC_018650.1 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase DeaD 644446 13691195 O3M_03165 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent RNA helicase DeaD YP_006768312.1 642557 D 1134782 CDS YP_006768313.1 410480767 13691196 644600..645844 1 NC_018650.1 COG0814 Amino acid permeases; tryptophan permease 645844 13691196 O3M_03170 Escherichia coli O104:H4 str. 2009EL-2050 tryptophan permease YP_006768313.1 644600 D 1134782 CDS YP_006768314.1 410480768 13691197 complement(645962..646969) 1 NC_018650.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein 646969 13691197 O3M_03175 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768314.1 645962 R 1134782 CDS YP_006768315.1 410480769 13691198 complement(647175..648053) 1 NC_018650.1 COG0826 Collagenase and related proteases; protease 648053 13691198 O3M_03180 Escherichia coli O104:H4 str. 2009EL-2050 protease YP_006768315.1 647175 R 1134782 CDS YP_006768316.1 410480770 13691199 complement(648062..649057) 1 NC_018650.1 COG0826 Collagenase and related proteases; peptidase, U32 family protein 649057 13691199 O3M_03185 Escherichia coli O104:H4 str. 2009EL-2050 peptidase, U32 family protein YP_006768316.1 648062 R 1134782 CDS YP_006768317.1 410480771 13691200 649266..649790 1 NC_018650.1 COG3154 Putative lipid carrier protein; lipid carrier protein 649790 13691200 O3M_03190 Escherichia coli O104:H4 str. 2009EL-2050 lipid carrier protein YP_006768317.1 649266 D 1134782 CDS YP_006768318.1 410480772 13691201 649784..650287 1 NC_018650.1 COG3153 Predicted acetyltransferase; hypothetical protein 650287 13691201 O3M_03195 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768318.1 649784 D 1134782 CDS YP_006768319.1 410480773 13691202 complement(650274..650576) 1 NC_018650.1 COG2827 Predicted endonuclease containing a URI domain; GIY-YIG nuclease superfamily protein 650576 13691202 O3M_03200 Escherichia coli O104:H4 str. 2009EL-2050 GIY-YIG nuclease superfamily protein YP_006768319.1 650274 R 1134782 CDS YP_006768320.1 410480774 13691203 650627..651070 1 NC_018650.1 COG3787 Uncharacterized protein conserved in bacteria; hypothetical protein 651070 13691203 O3M_03205 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768320.1 650627 D 1134782 CDS YP_006768321.1 410480775 13691204 complement(651050..651568) 1 NC_018650.1 COG0693 Putative intracellular protease/amidase; hypothetical protein 651568 13691204 O3M_03210 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768321.1 651050 R 1134782 CDS YP_006768322.1 410480776 13691205 651696..652331 1 NC_018650.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; nucleoside-diphosphate-sugar epimerase 652331 13691205 O3M_03215 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside-diphosphate-sugar epimerase YP_006768322.1 651696 D 1134782 CDS YP_006768323.1 410480777 13691206 652404..653444 1 NC_018650.1 COG0701 Predicted permeases; permease 653444 13691206 O3M_03220 Escherichia coli O104:H4 str. 2009EL-2050 permease YP_006768323.1 652404 D 1134782 CDS YP_006768324.1 410480778 13691207 complement(653558..654133) 1 NC_018650.1 COG2823 Predicted periplasmic or secreted lipoprotein; outer membrane lipoprotein 654133 13691207 O3M_03225 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006768324.1 653558 R 1134782 CDS YP_006768325.1 410480779 13691208 complement(654143..654733) 1 NC_018650.1 COG0279 Phosphoheptose isomerase; DnaA initiator-associating protein DiaA 654733 13691208 O3M_03230 Escherichia coli O104:H4 str. 2009EL-2050 DnaA initiator-associating protein DiaA YP_006768325.1 654143 R 1134782 CDS YP_006768326.1 410480780 13691209 complement(654753..655148) 1 NC_018650.1 COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein 655148 13691209 O3M_03235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768326.1 654753 R 1134782 CDS YP_006768327.1 410480781 13691210 complement(655106..657142) 1 NC_018650.1 COG3107 Putative lipoprotein; LppC family lipoprotein 657142 13691210 O3M_03240 Escherichia coli O104:H4 str. 2009EL-2050 LppC family lipoprotein YP_006768327.1 655106 R 1134782 CDS YP_006768328.1 410480782 13691211 657206..658066 1 NC_018650.1 COG0313 Predicted methyltransferases; SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase 658066 13691211 O3M_03245 Escherichia coli O104:H4 str. 2009EL-2050 SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase YP_006768328.1 657206 D 1134782 CDS YP_006768329.1 410480783 13691212 complement(658109..659200) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial protein 659200 13691212 O3M_03250 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein YP_006768329.1 658109 R 1134782 CDS YP_006768330.1 410480784 13691213 complement(659211..661727) 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; outer membrane protein 661727 13691213 O3M_03255 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein YP_006768330.1 659211 R 1134782 CDS YP_006768331.1 410480785 13691214 complement(661757..662452) 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; periplasmic pilin chaperone 662452 13691214 O3M_03260 Escherichia coli O104:H4 str. 2009EL-2050 periplasmic pilin chaperone YP_006768331.1 661757 R 1134782 CDS YP_006768332.1 410480786 13691215 complement(662532..663116) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 663116 13691215 O3M_03265 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006768332.1 662532 R 1134782 CDS YP_006768333.1 410480787 13691216 complement(663516..664271) 1 NC_018650.1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; galactosamine-6-phosphate isomerase 664271 13691216 O3M_03270 Escherichia coli O104:H4 str. 2009EL-2050 galactosamine-6-phosphate isomerase YP_006768333.1 663516 R 1134782 CDS YP_006768334.1 410480788 13691217 complement(664272..665063) 1 NC_018650.1 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system N-acetylgalactosamine-specific transporter subunit IID 665063 13691217 O3M_03275 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_006768334.1 664272 R 1134782 CDS YP_006768335.1 410480789 13691218 complement(665053..665856) 1 NC_018650.1 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system N-acetylgalactosamine-specific transporter subunit IIC 665856 13691218 O3M_03280 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_006768335.1 665053 R 1134782 CDS YP_006768336.1 410480790 13691219 complement(665895..666371) 1 NC_018650.1 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system N-acetylgalactosamine-specific transporter subunit IIB 666371 13691219 O3M_03285 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_006768336.1 665895 R 1134782 CDS YP_006768337.1 410480791 13691220 complement(666538..667398) 1 NC_018650.1 COG0191 Fructose/tagatose bisphosphate aldolase; tagatose-bisphosphate aldolase 667398 kbaY 13691220 kbaY Escherichia coli O104:H4 str. 2009EL-2050 tagatose-bisphosphate aldolase YP_006768337.1 666538 R 1134782 CDS YP_006768338.1 410480792 13691221 complement(667411..668565) 1 NC_018650.1 COG2222 Predicted phosphosugar isomerases; tagatose-6-phosphate ketose/aldose isomerase 668565 13691221 O3M_03295 Escherichia coli O104:H4 str. 2009EL-2050 tagatose-6-phosphate ketose/aldose isomerase YP_006768338.1 667411 R 1134782 CDS YP_006768339.1 410480793 13691222 complement(668915..670048) 1 NC_018650.1 COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 670048 13691222 O3M_03300 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylglucosamine-6-phosphate deacetylase YP_006768339.1 668915 R 1134782 CDS YP_006768340.1 410480794 13691223 complement(670045..670479) 1 NC_018650.1 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system transporter subunit IIA 670479 13691223 O3M_03305 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter subunit IIA YP_006768340.1 670045 R 1134782 CDS YP_006768341.1 410480795 13691224 complement(670497..671375) 1 NC_018650.1 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system hexose/hexosamine family transporter permease IID 671375 13691224 O3M_03310 Escherichia coli O104:H4 str. 2009EL-2050 PTS system hexose/hexosamine family transporter permease IID YP_006768341.1 670497 R 1134782 CDS YP_006768342.1 410480796 13691225 complement(671365..672144) 1 NC_018650.1 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system N-acetylgalactosamine-specific transporter subunit IIC 672144 13691225 O3M_03315 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_006768342.1 671365 R 1134782 CDS YP_006768343.1 410480797 13691226 complement(672155..672628) 1 NC_018650.1 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system N-acetylgalactosamine-specific transporter subunit IIB 672628 13691226 O3M_03320 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_006768343.1 672155 R 1134782 CDS YP_006768344.1 410480798 13691227 complement(672651..673931) 1 NC_018650.1 COG4573 Predicted tagatose 6-phosphate kinase; tagatose 6-phosphate aldolase subunit KbaZ 673931 13691227 O3M_03325 Escherichia coli O104:H4 str. 2009EL-2050 tagatose 6-phosphate aldolase subunit KbaZ YP_006768344.1 672651 R 1134782 CDS YP_006768345.1 410480799 13691228 674180..674989 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional regulator AgaR 674989 13691228 O3M_03330 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator AgaR YP_006768345.1 674180 D 1134782 CDS YP_006768346.1 410480800 13691229 complement(675044..675508) 1 NC_018650.1 hypothetical protein 675508 13691229 O3M_03335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768346.1 675044 R 1134782 CDS YP_006768347.1 410480801 13691230 complement(675508..675843) 1 NC_018650.1 COG2002 Regulators of stationary/sporulation gene expression; regulator PrlF 675843 13691230 O3M_03340 Escherichia coli O104:H4 str. 2009EL-2050 regulator PrlF YP_006768347.1 675508 R 1134782 CDS YP_006768348.1 410480802 13691231 complement(675992..677563) 1 NC_018650.1 COG2721 Altronate dehydratase; galactarate dehydratase 677563 13691231 O3M_03345 Escherichia coli O104:H4 str. 2009EL-2050 galactarate dehydratase YP_006768348.1 675992 R 1134782 CDS YP_006768349.1 410480803 13691232 677937..679271 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; galactarate transporter 679271 13691232 O3M_03350 Escherichia coli O104:H4 str. 2009EL-2050 galactarate transporter YP_006768349.1 677937 D 1134782 CDS YP_006768350.1 410480804 13691233 679287..680057 1 NC_018650.1 COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; alpha-dehydro-beta-deoxy-D-glucarate aldolase 680057 13691233 O3M_03355 Escherichia coli O104:H4 str. 2009EL-2050 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_006768350.1 679287 D 1134782 CDS YP_006768351.1 410480805 13691234 680087..680977 1 NC_018650.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; tartronate semialdehyde reductase 680977 garR 13691234 garR Escherichia coli O104:H4 str. 2009EL-2050 tartronate semialdehyde reductase YP_006768351.1 680087 D 1134782 CDS YP_006768352.1 410480806 13691235 681074..682219 1 NC_018650.1 COG1929 Glycerate kinase; glycerate kinase 682219 13691235 O3M_03365 Escherichia coli O104:H4 str. 2009EL-2050 glycerate kinase YP_006768352.1 681074 D 1134782 CDS YP_006768353.1 410480807 13691236 complement(682976..683956) 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 683956 13691236 O3M_03370 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006768353.1 682976 R 1134782 CDS YP_006768354.1 410480808 13691237 complement(684294..685481) 1 NC_018650.1 hypothetical protein 685481 13691237 O3M_03375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768354.1 684294 R 1134782 CDS YP_006768355.1 410480809 13691238 complement(685503..686042) 1 NC_018650.1 COG0443 Molecular chaperone; hypothetical protein 686042 13691238 O3M_03380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768355.1 685503 R 1134782 CDS YP_006768356.1 410480810 13691239 complement(686298..686516) 1 NC_018650.1 DNA-binding transcriptional activator TdcR 686516 13691239 O3M_03385 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator TdcR YP_006768356.1 686298 R 1134782 CDS YP_006768357.1 410480811 13691240 686831..687769 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional activator TdcA 687769 13691240 O3M_03390 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator TdcA YP_006768357.1 686831 D 1134782 CDS YP_006768358.1 410480812 13691241 687868..688857 1 NC_018650.1 COG1171 Threonine dehydratase; threonine dehydratase 688857 13691241 O3M_03395 Escherichia coli O104:H4 str. 2009EL-2050 threonine dehydratase YP_006768358.1 687868 D 1134782 CDS YP_006768359.1 410480813 13691242 688879..690210 1 NC_018650.1 COG0814 Amino acid permeases; threonine/serine transporter TdcC 690210 13691242 O3M_03400 Escherichia coli O104:H4 str. 2009EL-2050 threonine/serine transporter TdcC YP_006768359.1 688879 D 1134782 CDS YP_006768360.1 410480814 13691243 690236..691444 1 NC_018650.1 COG0282 Acetate kinase; propionate/acetate kinase 691444 13691243 O3M_03405 Escherichia coli O104:H4 str. 2009EL-2050 propionate/acetate kinase YP_006768360.1 690236 D 1134782 CDS YP_006768361.1 410480815 13691244 691478..693772 1 NC_018650.1 COG1882 Pyruvate-formate lyase; Keto-acid formate acetyltransferase 693772 13691244 O3M_03410 Escherichia coli O104:H4 str. 2009EL-2050 Keto-acid formate acetyltransferase YP_006768361.1 691478 D 1134782 CDS YP_006768362.1 410480816 13691245 693786..694175 1 NC_018650.1 COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease L-PSP 694175 13691245 O3M_03415 Escherichia coli O104:H4 str. 2009EL-2050 endoribonuclease L-PSP YP_006768362.1 693786 D 1134782 CDS YP_006768363.1 410480817 13691246 694247..695611 1 NC_018650.1 COG1760 L-serine deaminase; L-serine dehydratase TdcG 695611 13691246 O3M_03420 Escherichia coli O104:H4 str. 2009EL-2050 L-serine dehydratase TdcG YP_006768363.1 694247 D 1134782 CDS YP_006768364.1 410480818 13691247 695886..697217 1 NC_018650.1 COG0814 Amino acid permeases; transporter 697217 13691247 O3M_03425 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768364.1 695886 D 1134782 CDS YP_006768365.1 410480819 13691248 697245..698555 1 NC_018650.1 COG3681 Uncharacterized conserved protein; hypothetical protein 698555 13691248 O3M_03430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768365.1 697245 D 1134782 CDS YP_006768366.1 410480820 13691249 complement(698616..698780) 1 NC_018650.1 hypothetical protein 698780 13691249 O3M_03435 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768366.1 698616 R 1134782 CDS YP_006768367.1 410480821 13691250 complement(698803..699504) 1 NC_018650.1 COG1741 Pirin-related protein; pirin-related protein 699504 13691250 O3M_03440 Escherichia coli O104:H4 str. 2009EL-2050 pirin-related protein YP_006768367.1 698803 R 1134782 CDS YP_006768368.1 410480822 13691251 699609..700505 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 700505 13691251 O3M_03445 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006768368.1 699609 D 1134782 CDS YP_006768369.1 410480823 13691252 complement(700549..701052) 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 701052 13691252 O3M_03450 Escherichia coli O104:H4 str. 2009EL-2050 IS1 transposase InsAB' YP_006768369.1 700549 R 1134782 CDS YP_006768370.1 410480824 13691253 complement(700971..701246) 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 701246 13691253 O3M_03455 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006768370.1 700971 R 1134782 CDS YP_006768371.1 410480825 13691254 complement(701356..701721) 1 NC_018650.1 COG3152 Predicted membrane protein; hypothetical protein 701721 13691254 O3M_03460 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768371.1 701356 R 1134782 CDS YP_006768372.1 410480826 13691255 complement(702014..703000) 1 NC_018650.1 COG0435 Predicted glutathione S-transferase; transferase 703000 13691255 O3M_03465 Escherichia coli O104:H4 str. 2009EL-2050 transferase YP_006768372.1 702014 R 1134782 CDS YP_006768373.1 410480827 13691256 complement(703070..703462) 1 NC_018650.1 COG2259 Predicted membrane protein; hypothetical protein 703462 13691256 O3M_03470 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768373.1 703070 R 1134782 CDS YP_006768374.1 410480828 13691257 complement(703648..703947) 1 NC_018650.1 hypothetical protein 703947 13691257 O3M_03475 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768374.1 703648 R 1134782 CDS YP_006768375.1 410480829 13691258 complement(703937..704341) 1 NC_018650.1 hypothetical protein 704341 13691258 O3M_03480 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768375.1 703937 R 1134782 CDS YP_006768376.1 410480830 13691259 complement(704344..704649) 1 NC_018650.1 COG4575 Uncharacterized conserved protein; hypothetical protein 704649 13691259 O3M_03485 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768376.1 704344 R 1134782 CDS YP_006768377.1 410480831 13691260 complement(704687..705055) 1 NC_018650.1 hypothetical protein 705055 13691260 O3M_03490 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768377.1 704687 R 1134782 CDS YP_006768378.1 410480832 13691261 complement(705202..705585) 1 NC_018650.1 EnvZ/OmpR regulon moderator 705585 13691261 O3M_03495 Escherichia coli O104:H4 str. 2009EL-2050 EnvZ/OmpR regulon moderator YP_006768378.1 705202 R 1134782 CDS YP_006768379.1 410480833 13691262 complement(705589..706251) 1 NC_018650.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 706251 13691262 O3M_03500 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768379.1 705589 R 1134782 CDS YP_006768380.1 410480834 13691263 complement(706596..707372) 1 NC_018650.1 COG2186 Transcriptional regulators; DNA-binding transcriptional repressor ExuR 707372 13691263 O3M_03505 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor ExuR YP_006768380.1 706596 R 1134782 CDS YP_006768381.1 410480835 13691264 707668..708384 1 NC_018650.1 fimbrial protein 708384 13691264 O3M_03510 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein YP_006768381.1 707668 D 1134782 CDS YP_006768382.1 410480836 13691265 708414..708914 1 NC_018650.1 fimbrial subunit 708914 13691265 O3M_03515 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial subunit YP_006768382.1 708414 D 1134782 CDS YP_006768383.1 410480837 13691266 708988..711690 1 NC_018650.1 hypothetical protein 711690 13691266 O3M_03520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768383.1 708988 D 1134782 CDS YP_006768384.1 410480838 13691267 711687..712775 1 NC_018650.1 hypothetical protein 712775 13691267 O3M_03525 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768384.1 711687 D 1134782 CDS YP_006768385.1 410480839 13691268 complement(712863..714161) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; hexuronate transporter 714161 13691268 O3M_03530 Escherichia coli O104:H4 str. 2009EL-2050 hexuronate transporter YP_006768385.1 712863 R 1134782 CDS YP_006768386.1 410480840 13691269 714644..716056 1 NC_018650.1 COG1904 Glucuronate isomerase; glucuronate isomerase 716056 13691269 O3M_03535 Escherichia coli O104:H4 str. 2009EL-2050 glucuronate isomerase YP_006768386.1 714644 D 1134782 CDS YP_006768387.1 410480841 13691270 716071..717558 1 NC_018650.1 COG2721 Altronate dehydratase; altronate hydrolase 717558 13691270 O3M_03540 Escherichia coli O104:H4 str. 2009EL-2050 altronate hydrolase YP_006768387.1 716071 D 1134782 CDS YP_006768388.1 410480842 13691271 717641..718192 1 NC_018650.1 inner membrane protein 718192 13691271 O3M_03545 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768388.1 717641 D 1134782 CDS YP_006768389.1 410480843 13691272 complement(718197..719441) 1 NC_018650.1 COG3633 Na+/serine symporter; serine/threonine transporter SstT 719441 13691272 O3M_03550 Escherichia coli O104:H4 str. 2009EL-2050 serine/threonine transporter SstT YP_006768389.1 718197 R 1134782 CDS YP_006768390.1 410480844 13691273 complement(719840..720805) 1 NC_018650.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; inner membrane protein 720805 13691273 O3M_03555 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768390.1 719840 R 1134782 CDS YP_006768391.1 410480845 13691274 complement(721088..722074) 1 NC_018650.1 COG0673 Predicted dehydrogenases and related proteins; NAD(P)-binding dehydrogenase 722074 13691274 O3M_03560 Escherichia coli O104:H4 str. 2009EL-2050 NAD(P)-binding dehydrogenase YP_006768391.1 721088 R 1134782 CDS YP_006768392.1 410480846 13691275 complement(722153..722836) 1 NC_018650.1 COG2949 Uncharacterized membrane protein; thioredoxin-like protein 722836 13691275 O3M_03565 Escherichia coli O104:H4 str. 2009EL-2050 thioredoxin-like protein YP_006768392.1 722153 R 1134782 CDS YP_006768393.1 410480847 13691276 complement(722913..723416) 1 NC_018650.1 COG1451 Predicted metal-dependent hydrolase; hypothetical protein 723416 13691276 O3M_03570 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768393.1 722913 R 1134782 CDS YP_006768394.1 410480848 13691277 723501..724637 1 NC_018650.1 COG2813 16S RNA G1207 methylase RsmC; SAM-dependent 23S ribosomal RNA mG1835 methyltransferase 724637 13691277 O3M_03575 Escherichia coli O104:H4 str. 2009EL-2050 SAM-dependent 23S ribosomal RNA mG1835 methyltransferase YP_006768394.1 723501 D 1134782 CDS YP_006768395.1 410480849 13691278 724741..724911 1 NC_018650.1 hypothetical protein 724911 13691278 O3M_03580 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768395.1 724741 D 1134782 CDS YP_006768396.1 410480850 13691279 724908..725324 1 NC_018650.1 COG5499 Predicted transcription regulator containing HTH domain; DNA-binding transcriptional regulator 725324 13691279 O3M_03585 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768396.1 724908 D 1134782 CDS YP_006768397.1 410480851 13691280 complement(725369..727387) 1 NC_018650.1 COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; 2,4-dienoyl-CoA reductase 727387 13691280 O3M_03590 Escherichia coli O104:H4 str. 2009EL-2050 2,4-dienoyl-CoA reductase YP_006768397.1 725369 R 1134782 CDS YP_006768398.1 410480852 13691281 complement(727713..730064) 1 NC_018650.1 COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; alpha-glucosidase 730064 13691281 O3M_03595 Escherichia coli O104:H4 str. 2009EL-2050 alpha-glucosidase YP_006768398.1 727713 R 1134782 CDS YP_006768399.1 410480853 13691282 complement(730081..731151) 1 NC_018650.1 hypothetical protein 731151 13691282 O3M_03600 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768399.1 730081 R 1134782 CDS YP_006768400.1 410480854 13691283 complement(731285..732718) 1 NC_018650.1 COG0531 Amino acid transporters; transporter 732718 13691283 O3M_03605 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768400.1 731285 R 1134782 CDS YP_006768401.1 410480855 13691284 complement(732781..733230) 1 NC_018650.1 COG2731 Beta-galactosidase, beta subunit; cryptic beta-D-galactosidase subunit beta 733230 ebgC 13691284 ebgC Escherichia coli O104:H4 str. 2009EL-2050 cryptic beta-D-galactosidase subunit beta YP_006768401.1 732781 R 1134782 CDS YP_006768402.1 410480856 13691285 complement(733227..736319) 1 NC_018650.1 COG3250 Beta-galactosidase/beta-glucuronidase; cryptic beta-D-galactosidase subunit alpha 736319 ebgA 13691285 ebgA Escherichia coli O104:H4 str. 2009EL-2050 cryptic beta-D-galactosidase subunit alpha YP_006768402.1 733227 R 1134782 CDS YP_006768403.1 410480857 13691286 complement(736503..737486) 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional repressor EbgR 737486 13691286 O3M_03620 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor EbgR YP_006768403.1 736503 R 1134782 CDS YP_006768404.1 410480858 13691287 737705..738037 1 NC_018650.1 COG0073 EMAP domain; tRNA-binding protein 738037 13691287 O3M_03625 Escherichia coli O104:H4 str. 2009EL-2050 tRNA-binding protein YP_006768404.1 737705 D 1134782 CDS YP_006768405.1 410480859 13691288 complement(738079..739485) 1 NC_018650.1 COG4992 Ornithine/acetylornithine aminotransferase; putrescine--2-oxoglutarate aminotransferase 739485 13691288 O3M_03630 Escherichia coli O104:H4 str. 2009EL-2050 putrescine--2-oxoglutarate aminotransferase YP_006768405.1 738079 R 1134782 CDS YP_006768406.1 410480860 13691289 739876..741396 1 NC_018650.1 COG2202 FOG: PAS/PAC domain; signal transducer for aerotaxis/methyl accepting chemotaxis protein 741396 13691289 O3M_03635 Escherichia coli O104:H4 str. 2009EL-2050 signal transducer for aerotaxis/methyl accepting chemotaxis protein YP_006768406.1 739876 D 1134782 CDS YP_006768407.1 410480861 13691290 complement(741550..742173) 1 NC_018650.1 COG1695 Predicted transcriptional regulators; transcriptional regulator 742173 13691290 O3M_03640 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768407.1 741550 R 1134782 CDS YP_006768408.1 410480862 13691291 742450..743214 1 NC_018650.1 COG2375 Siderophore-interacting protein; siderophore-interacting protein 743214 13691291 O3M_03645 Escherichia coli O104:H4 str. 2009EL-2050 siderophore-interacting protein YP_006768408.1 742450 D 1134782 CDS YP_006768409.1 410480863 13691293 743468..743974 1 NC_018650.1 COG3663 G:T/U mismatch-specific DNA glycosylase; G/U mismatch-specific DNA glycosylase 743974 13691293 O3M_03650 Escherichia coli O104:H4 str. 2009EL-2050 G/U mismatch-specific DNA glycosylase YP_006768409.1 743468 D 1134782 CDS YP_006768410.1 410480864 13691294 complement(744052..745893) 1 NC_018650.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor RpoD 745893 13691294 O3M_03655 Escherichia coli O104:H4 str. 2009EL-2050 RNA polymerase sigma factor RpoD YP_006768410.1 744052 R 1134782 CDS YP_006768411.1 410480865 13691295 complement(746088..747833) 1 NC_018650.1 COG0358 DNA primase (bacterial type); DNA primase 747833 dnaG 13691295 dnaG Escherichia coli O104:H4 str. 2009EL-2050 DNA primase YP_006768411.1 746088 R 1134782 CDS YP_006768412.1 410480866 13691296 complement(747944..748159) 1 NC_018650.1 COG0828 Ribosomal protein S21; 30S ribosomal protein S21 748159 rpsU 13691296 rpsU Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S21 YP_006768412.1 747944 R 1134782 CDS YP_006768413.1 410480867 13691297 748396..749409 1 NC_018650.1 COG0533 Metal-dependent proteases with possible chaperone activity; UGMP family protein 749409 13691297 O3M_03670 Escherichia coli O104:H4 str. 2009EL-2050 UGMP family protein YP_006768413.1 748396 D 1134782 CDS YP_006768414.1 410480868 13691298 complement(749452..750915) 1 NC_018650.1 COG0471 Di- and tricarboxylate transporters; tartrate:succinate antiporter 750915 13691298 O3M_03675 Escherichia coli O104:H4 str. 2009EL-2050 tartrate:succinate antiporter YP_006768414.1 749452 R 1134782 CDS YP_006768415.1 410480869 13691299 complement(750964..751569) 1 NC_018650.1 COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain; L(+)-tartrate dehydratase subunit beta 751569 13691299 O3M_03680 Escherichia coli O104:H4 str. 2009EL-2050 L(+)-tartrate dehydratase subunit beta YP_006768415.1 750964 R 1134782 CDS YP_006768416.1 410480870 13691300 complement(751566..752477) 1 NC_018650.1 COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; tartrate dehydratase subunit alpha 752477 13691300 O3M_03685 Escherichia coli O104:H4 str. 2009EL-2050 tartrate dehydratase subunit alpha YP_006768416.1 751566 R 1134782 CDS YP_006768417.1 410480871 13691301 752684..753616 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional activator TtdR 753616 13691301 O3M_03690 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator TtdR YP_006768417.1 752684 D 1134782 CDS YP_006768418.1 410480872 13691302 complement(753629..754246) 1 NC_018650.1 COG0344 Predicted membrane protein; glycerol-3-phosphate acyltransferase PlsY 754246 13691302 O3M_03695 Escherichia coli O104:H4 str. 2009EL-2050 glycerol-3-phosphate acyltransferase PlsY YP_006768418.1 753629 R 1134782 CDS YP_006768419.1 410480873 13691303 754351..754719 1 NC_018650.1 COG1539 Dihydroneopterin aldolase; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 754719 folB 13691303 folB Escherichia coli O104:H4 str. 2009EL-2050 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_006768419.1 754351 D 1134782 CDS YP_006768420.1 410480874 13691304 754810..755631 1 NC_018650.1 COG1968 Uncharacterized bacitracin resistance protein; undecaprenyl pyrophosphate phosphatase 755631 13691304 O3M_03705 Escherichia coli O104:H4 str. 2009EL-2050 undecaprenyl pyrophosphate phosphatase YP_006768420.1 754810 D 1134782 CDS YP_006768421.1 410480875 13691305 complement(755794..757032) 1 NC_018650.1 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 757032 cca 13691305 cca Escherichia coli O104:H4 str. 2009EL-2050 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_006768421.1 755794 R 1134782 CDS YP_006768422.1 410480876 13691306 complement(757096..757716) 1 NC_018650.1 COG3103 SH3 domain protein; SH3 domain-containing protein 757716 13691306 O3M_03715 Escherichia coli O104:H4 str. 2009EL-2050 SH3 domain-containing protein YP_006768422.1 757096 R 1134782 CDS YP_006768423.1 410480877 13691307 757958..759259 1 NC_018650.1 COG3025 Uncharacterized conserved protein; adenylate cyclase 759259 13691307 O3M_03720 Escherichia coli O104:H4 str. 2009EL-2050 adenylate cyclase YP_006768423.1 757958 D 1134782 CDS YP_006768424.1 410480878 13691308 759282..762122 1 NC_018650.1 COG1391 Glutamine synthetase adenylyltransferase; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 762122 13691308 O3M_03725 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_006768424.1 759282 D 1134782 CDS YP_006768425.1 410480879 13691309 762170..763603 1 NC_018650.1 COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 763603 13691309 O3M_03730 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_006768425.1 762170 D 1134782 CDS YP_006768426.1 410480880 13691310 complement(764397..766058) 1 NC_018650.1 COG2268 Uncharacterized protein conserved in bacteria; hypothetical protein 766058 13691310 O3M_03735 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768426.1 764397 R 1134782 CDS YP_006768427.1 410480881 13691311 complement(766085..766714) 1 NC_018650.1 inner membrane protein 766714 13691311 O3M_03740 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768427.1 766085 R 1134782 CDS YP_006768428.1 410480882 13691312 766983..767183 1 NC_018650.1 glycogen synthesis protein GlgS 767183 13691312 O3M_03745 Escherichia coli O104:H4 str. 2009EL-2050 glycogen synthesis protein GlgS YP_006768428.1 766983 D 1134782 CDS YP_006768429.1 410480883 13691313 complement(767226..768290) 1 NC_018650.1 hypothetical protein 768290 13691313 O3M_03750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768429.1 767226 R 1134782 CDS YP_006768430.1 410480884 13691314 complement(768292..769041) 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; periplasmic pilin chaperone 769041 13691314 O3M_03755 Escherichia coli O104:H4 str. 2009EL-2050 periplasmic pilin chaperone YP_006768430.1 768292 R 1134782 CDS YP_006768431.1 410480885 13691315 complement(769057..771561) 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein 771561 13691315 O3M_03760 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane usher protein YP_006768431.1 769057 R 1134782 CDS YP_006768432.1 410480886 13691316 complement(771621..772172) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial protein 772172 13691316 O3M_03765 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein YP_006768432.1 771621 R 1134782 CDS YP_006768433.1 410480887 13691317 complement(772455..772745) 1 NC_018650.1 COG2960 Uncharacterized protein conserved in bacteria; hypothetical protein 772745 13691317 O3M_03770 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768433.1 772455 R 1134782 CDS YP_006768434.1 410480888 13691318 773119..773772 1 NC_018650.1 COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase 773772 ribB 13691318 ribB Escherichia coli O104:H4 str. 2009EL-2050 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_006768434.1 773119 D 1134782 CDS YP_006768435.1 410480889 13691319 774033..774203 1 NC_018650.1 hypothetical protein 774203 13691319 O3M_03780 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768435.1 774033 D 1134782 CDS YP_006768436.1 410480890 13691320 complement(774261..775034) 1 NC_018650.1 COG0428 Predicted divalent heavy-metal cations transporter; zinc transporter ZupT 775034 13691320 O3M_03785 Escherichia coli O104:H4 str. 2009EL-2050 zinc transporter ZupT YP_006768436.1 774261 R 1134782 CDS YP_006768437.1 410480891 13691321 775177..775965 1 NC_018650.1 COG3384 Uncharacterized conserved protein; LigB family dioxygenase 775965 13691321 O3M_03790 Escherichia coli O104:H4 str. 2009EL-2050 LigB family dioxygenase YP_006768437.1 775177 D 1134782 CDS YP_006768438.1 410480892 13691322 complement(776003..777163) 1 NC_018650.1 COG0754 Glutathionylspermidine synthase; hypothetical protein 777163 13691322 O3M_03795 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768438.1 776003 R 1134782 CDS YP_006768439.1 410480893 13691323 complement(777169..777840) 1 NC_018650.1 COG5463 Predicted integral membrane protein; hypothetical protein 777840 13691323 O3M_03800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768439.1 777169 R 1134782 CDS YP_006768440.1 410480894 13691324 complement(777988..779469) 1 NC_018650.1 COG1538 Outer membrane protein; outer membrane channel protein 779469 tolC 13691324 tolC Escherichia coli O104:H4 str. 2009EL-2050 outer membrane channel protein YP_006768440.1 777988 R 1134782 CDS YP_006768441.1 410480895 13691325 779674..780303 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; ADP-ribose pyrophosphatase NudF 780303 nudF 13691325 nudF Escherichia coli O104:H4 str. 2009EL-2050 ADP-ribose pyrophosphatase NudF YP_006768441.1 779674 D 1134782 CDS YP_006768442.1 410480896 13691326 780304..780726 1 NC_018650.1 COG3151 Uncharacterized protein conserved in bacteria; dehydrogenase 780726 13691326 O3M_03815 Escherichia coli O104:H4 str. 2009EL-2050 dehydrogenase YP_006768442.1 780304 D 1134782 CDS YP_006768443.1 410480897 13691327 780751..781578 1 NC_018650.1 COG1409 Predicted phosphohydrolases; cyclic 3',5'-adenosine monophosphate phosphodiesterase 781578 13691327 O3M_03820 Escherichia coli O104:H4 str. 2009EL-2050 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_006768443.1 780751 D 1134782 CDS YP_006768444.1 410480898 13691328 781578..782159 1 NC_018650.1 COG3150 Predicted esterase; esterase YqiA 782159 13691328 O3M_03825 Escherichia coli O104:H4 str. 2009EL-2050 esterase YqiA YP_006768444.1 781578 D 1134782 CDS YP_006768445.1 410480899 13691329 782188..784080 1 NC_018650.1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA topoisomerase IV subunit B 784080 13691329 O3M_03830 Escherichia coli O104:H4 str. 2009EL-2050 DNA topoisomerase IV subunit B YP_006768445.1 782188 D 1134782 CDS YP_006768446.1 410480900 13691330 complement(784128..784442) 1 NC_018650.1 COG1359 Uncharacterized conserved protein; hypothetical protein 784442 13691330 O3M_03835 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768446.1 784128 R 1134782 CDS YP_006768447.1 410480901 13691331 complement(784473..785054) 1 NC_018650.1 COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); Modulator of drug activity B 785054 13691331 O3M_03840 Escherichia coli O104:H4 str. 2009EL-2050 Modulator of drug activity B YP_006768447.1 784473 R 1134782 CDS YP_006768448.1 410480902 13691332 785373..785705 1 NC_018650.1 hypothetical protein 785705 13691332 O3M_03845 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768448.1 785373 D 1134782 CDS YP_006768449.1 410480903 13691333 complement(785751..787100) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor protein QseC 787100 13691333 O3M_03850 Escherichia coli O104:H4 str. 2009EL-2050 sensor protein QseC YP_006768449.1 785751 R 1134782 CDS YP_006768450.1 410480904 13691334 complement(787097..787756) 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator QseB 787756 13691334 O3M_03855 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator QseB YP_006768450.1 787097 R 1134782 CDS YP_006768451.1 410480905 13691335 787908..788300 1 NC_018650.1 COG3111 Uncharacterized conserved protein; hypothetical protein 788300 13691335 O3M_03860 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768451.1 787908 D 1134782 CDS YP_006768452.1 410480906 13691336 788353..788835 1 NC_018650.1 COG3449 DNA gyrase inhibitor; transcriptional regulator 788835 13691336 O3M_03865 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768452.1 788353 D 1134782 CDS YP_006768453.1 410480907 13691337 789381..791639 1 NC_018650.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA topoisomerase IV subunit A 791639 13691337 O3M_03870 Escherichia coli O104:H4 str. 2009EL-2050 DNA topoisomerase IV subunit A YP_006768453.1 789381 D 1134782 CDS YP_006768454.1 410480908 13691338 791872..792609 1 NC_018650.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 792609 13691338 O3M_03875 Escherichia coli O104:H4 str. 2009EL-2050 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_006768454.1 791872 D 1134782 CDS YP_006768455.1 410480909 13691339 792684..794096 1 NC_018650.1 COG2132 Putative multicopper oxidases; FtsI repressor 794096 13691339 O3M_03880 Escherichia coli O104:H4 str. 2009EL-2050 FtsI repressor YP_006768455.1 792684 D 1134782 CDS YP_006768456.1 410480910 13691340 794207..796426 1 NC_018650.1 COG1032 Fe-S oxidoreductase; hypothetical protein 796426 13691340 O3M_03885 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768456.1 794207 D 1134782 CDS YP_006768457.1 410480911 13691341 complement(796469..796726) 1 NC_018650.1 outer membrane lipoprotein 796726 13691341 O3M_03890 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006768457.1 796469 R 1134782 CDS YP_006768458.1 410480912 13691342 complement(796777..797703) 1 NC_018650.1 hypothetical protein 797703 13691342 O3M_03895 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768458.1 796777 R 1134782 CDS YP_006768459.1 410480913 13691343 complement(797903..798730) 1 NC_018650.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-diketo-D-gluconate reductase A 798730 dkgA 13691343 dkgA Escherichia coli O104:H4 str. 2009EL-2050 2,5-diketo-D-gluconate reductase A YP_006768459.1 797903 R 1134782 CDS YP_006768460.1 410480914 13691344 complement(798835..799998) 1 NC_018650.1 COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; aldehyde reductase 799998 13691344 O3M_03905 Escherichia coli O104:H4 str. 2009EL-2050 aldehyde reductase YP_006768460.1 798835 R 1134782 CDS YP_006768461.1 410480915 13691345 800049..800195 1 NC_018650.1 hypothetical protein 800195 13691345 O3M_03910 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768461.1 800049 D 1134782 CDS YP_006768462.1 410480916 13691346 800135..801091 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 801091 13691346 O3M_03915 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768462.1 800135 D 1134782 CDS YP_006768463.1 410480917 13691347 complement(801131..801790) 1 NC_018650.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 801790 13691347 O3M_03920 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768463.1 801131 R 1134782 CDS YP_006768464.1 410480918 13691348 complement(801930..803117) 1 NC_018650.1 COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine beta-lyase 803117 13691348 O3M_03925 Escherichia coli O104:H4 str. 2009EL-2050 cystathionine beta-lyase YP_006768464.1 801930 R 1134782 CDS YP_006768465.1 410480919 13691349 803369..804103 1 NC_018650.1 COG0811 Biopolymer transport proteins; biopolymer transport protein ExbB 804103 13691349 O3M_03930 Escherichia coli O104:H4 str. 2009EL-2050 biopolymer transport protein ExbB YP_006768465.1 803369 D 1134782 CDS YP_006768466.1 410480920 13691350 804110..804535 1 NC_018650.1 COG0848 Biopolymer transport protein; biopolymer transport protein ExbD 804535 13691350 O3M_03935 Escherichia coli O104:H4 str. 2009EL-2050 biopolymer transport protein ExbD YP_006768466.1 804110 D 1134782 CDS YP_006768467.1 410480921 13691351 complement(804574..805458) 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 805458 13691351 O3M_03940 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006768467.1 804574 R 1134782 CDS YP_006768468.1 410480922 13691352 805649..806143 1 NC_018650.1 COG2862 Predicted membrane protein; hypothetical protein 806143 13691352 O3M_03945 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768468.1 805649 D 1134782 CDS YP_006768469.1 410480923 13691353 complement(806183..807223) 1 NC_018650.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); L-glyceraldehyde 3-phosphate reductase 807223 13691353 O3M_03950 Escherichia coli O104:H4 str. 2009EL-2050 L-glyceraldehyde 3-phosphate reductase YP_006768469.1 806183 R 1134782 CDS YP_006768470.1 410480924 13691354 807380..808267 1 NC_018650.1 COG0412 Dienelactone hydrolase and related enzymes; hypothetical protein 808267 13691354 O3M_03955 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768470.1 807380 D 1134782 CDS YP_006768471.1 410480925 13691355 808386..808673 1 NC_018650.1 hypothetical protein 808673 13691355 O3M_03960 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768471.1 808386 D 1134782 CDS YP_006768472.1 410480926 13691356 808862..809980 1 NC_018650.1 COG1740 Ni,Fe-hydrogenase I small subunit; hydrogenase 2 small subunit 809980 13691356 O3M_03965 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 2 small subunit YP_006768472.1 808862 D 1134782 CDS YP_006768473.1 410480927 13691357 809983..810969 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; hydrogenase 2 protein HybA 810969 13691357 O3M_03970 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 2 protein HybA YP_006768473.1 809983 D 1134782 CDS YP_006768474.1 410480928 13691358 810959..812137 1 NC_018650.1 COG5557 Polysulphide reductase; hydrogenase 2 b cytochrome subunit 812137 13691358 O3M_03975 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 2 b cytochrome subunit YP_006768474.1 810959 D 1134782 CDS YP_006768475.1 410480929 13691359 812134..813837 1 NC_018650.1 COG0374 Ni,Fe-hydrogenase I large subunit; hydrogenase 2 large subunit 813837 13691359 O3M_03980 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 2 large subunit YP_006768475.1 812134 D 1134782 CDS YP_006768476.1 410480930 13691360 813837..814331 1 NC_018650.1 COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 2 maturation endopeptidase 814331 hybD 13691360 hybD Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 2 maturation endopeptidase YP_006768476.1 813837 D 1134782 CDS YP_006768477.1 410480931 13691361 814324..814812 1 NC_018650.1 hydrogenase 2-specific chaperone 814812 13691361 O3M_03990 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 2-specific chaperone YP_006768477.1 814324 D 1134782 CDS YP_006768478.1 410480932 13691362 814805..815146 1 NC_018650.1 COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); hydrogenase nickel incorporation protein HybF 815146 13691362 O3M_03995 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase nickel incorporation protein HybF YP_006768478.1 814805 D 1134782 CDS YP_006768479.1 410480933 13691363 815159..815407 1 NC_018650.1 COG0298 Hydrogenase maturation factor; hydrogenase 2 accessory protein HypG 815407 13691363 O3M_04000 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 2 accessory protein HypG YP_006768479.1 815159 D 1134782 CDS YP_006768480.1 410480934 13691364 complement(815529..816509) 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 816509 13691364 O3M_04005 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006768480.1 815529 R 1134782 CDS YP_006768481.1 410480935 13691365 complement(816809..817675) 1 NC_018650.1 COG0625 Glutathione S-transferase; S-transferase 817675 13691365 O3M_04010 Escherichia coli O104:H4 str. 2009EL-2050 S-transferase YP_006768481.1 816809 R 1134782 CDS YP_006768482.1 410480936 13691366 817880..819739 1 NC_018650.1 COG0754 Glutathionylspermidine synthase; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 819739 13691366 O3M_04015 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_006768482.1 817880 D 1134782 CDS YP_006768483.1 410480937 13691367 820031..821530 1 NC_018650.1 COG0306 Phosphate/sulphate permeases; phosphate transporter 821530 13691367 O3M_04020 Escherichia coli O104:H4 str. 2009EL-2050 phosphate transporter YP_006768483.1 820031 D 1134782 CDS YP_006768484.1 410480938 13691368 complement(821579..822271) 1 NC_018650.1 COG0125 Thymidylate kinase; hypothetical protein 822271 13691368 O3M_04025 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768484.1 821579 R 1134782 CDS YP_006768485.1 410480939 13691369 822445..823158 1 NC_018650.1 nucleoside triphosphate hydrolase domain; COG0125 Thymidylate kinase; lipoprotein 823158 13691369 O3M_04030 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006768485.1 822445 D 1134782 CDS YP_006768486.1 410480940 13691370 823190..823948 1 NC_018650.1 COG0178 Excinuclease ATPase subunit; hypothetical protein 823948 13691370 O3M_04035 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768486.1 823190 D 1134782 CDS YP_006768487.1 410480941 13691371 823994..825343 1 NC_018650.1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; inner membrane protein 825343 13691371 O3M_04040 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768487.1 823994 D 1134782 CDS YP_006768488.1 410480942 13691372 825343..826167 1 NC_018650.1 COG0372 Citrate synthase; hypothetical protein 826167 13691372 O3M_04045 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768488.1 825343 D 1134782 CDS YP_006768489.1 410480943 13691373 826179..826739 1 NC_018650.1 COG3054 Predicted transcriptional regulator; transcriptional regulator 826739 13691373 O3M_04050 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768489.1 826179 D 1134782 CDS YP_006768490.1 410480944 13691374 826770..827840 1 NC_018650.1 COG0795 Predicted permeases; hypothetical protein 827840 13691374 O3M_04055 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768490.1 826770 D 1134782 CDS YP_006768491.1 410480945 13691375 827837..828916 1 NC_018650.1 COG0795 Predicted permeases; hypothetical protein 828916 13691375 O3M_04060 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768491.1 827837 D 1134782 CDS YP_006768492.1 410480946 13691376 complement(828951..830123) 1 NC_018650.1 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; hypothetical protein 830123 13691376 O3M_04065 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768492.1 828951 R 1134782 CDS YP_006768493.1 410480947 13691377 complement(830123..830371) 1 NC_018650.1 COG0236 Acyl carrier protein; hypothetical protein 830371 13691377 O3M_04070 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768493.1 830123 R 1134782 CDS YP_006768494.1 410480948 13691378 complement(830403..831317) 1 NC_018650.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 831317 13691378 O3M_04075 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768494.1 830403 R 1134782 CDS YP_006768495.1 410480949 13691379 complement(831314..833002) 1 NC_018650.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; acyl-CoA synthetase 833002 13691379 O3M_04080 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA synthetase YP_006768495.1 831314 R 1134782 CDS YP_006768496.1 410480950 13691380 833406..834548 1 NC_018650.1 DNA-binding transcriptional regulator 834548 13691380 O3M_04085 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768496.1 833406 D 1134782 CDS YP_006768497.1 410480951 13691381 complement(834555..835319) 1 NC_018650.1 COG2186 Transcriptional regulators; DNA-binding transcriptional regulator GlcC 835319 13691381 O3M_04090 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator GlcC YP_006768497.1 834555 R 1134782 CDS YP_006768498.1 410480952 13691382 835570..837069 1 NC_018650.1 COG0277 FAD/FMN-containing dehydrogenases; glycolate oxidase subunit GlcD 837069 13691382 O3M_04095 Escherichia coli O104:H4 str. 2009EL-2050 glycolate oxidase subunit GlcD YP_006768498.1 835570 D 1134782 CDS YP_006768499.1 410480953 13691383 837069..838121 1 NC_018650.1 COG0277 FAD/FMN-containing dehydrogenases; glycolate oxidase FAD binding subunit 838121 glcE 13691383 glcE Escherichia coli O104:H4 str. 2009EL-2050 glycolate oxidase FAD binding subunit YP_006768499.1 837069 D 1134782 CDS YP_006768500.1 410480954 13691384 838132..839355 1 NC_018650.1 COG0247 Fe-S oxidoreductase; glycolate oxidase iron-sulfur subunit 839355 glcF 13691384 glcF Escherichia coli O104:H4 str. 2009EL-2050 glycolate oxidase iron-sulfur subunit YP_006768500.1 838132 D 1134782 CDS YP_006768501.1 410480955 13691385 839360..839764 1 NC_018650.1 COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol; hypothetical protein 839764 13691385 O3M_04110 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768501.1 839360 D 1134782 CDS YP_006768502.1 410480956 13691386 839786..841957 1 NC_018650.1 COG2225 Malate synthase; malate synthase G 841957 13691386 O3M_04115 Escherichia coli O104:H4 str. 2009EL-2050 malate synthase G YP_006768502.1 839786 D 1134782 CDS YP_006768503.1 410480957 13691387 842313..843995 1 NC_018650.1 COG1620 L-lactate permease; glycolate transporter 843995 13691387 O3M_04120 Escherichia coli O104:H4 str. 2009EL-2050 glycolate transporter YP_006768503.1 842313 D 1134782 CDS YP_006768504.1 410480958 13691388 complement(844121..844330) 1 NC_018650.1 hypothetical protein 844330 13691388 O3M_04125 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768504.1 844121 R 1134782 CDS YP_006768505.1 410480959 13691389 844613..849046 1 NC_018650.1 inner membrane lipoprotein 849046 13691389 O3M_04130 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane lipoprotein YP_006768505.1 844613 D 1134782 CDS YP_006768506.1 410480960 13691390 849186..849995 1 NC_018650.1 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; bifunctional prepilin leader peptidase/methylase 849995 13691390 O3M_04135 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional prepilin leader peptidase/methylase YP_006768506.1 849186 D 1134782 CDS YP_006768507.1 410480961 13691391 850061..850471 1 NC_018650.1 hypothetical protein 850471 13691391 O3M_04140 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768507.1 850061 D 1134782 CDS YP_006768508.1 410480962 13691392 850489..851448 1 NC_018650.1 COG3031 Type II secretory pathway, component PulC; type II secretion protein GspC 851448 13691392 O3M_04145 Escherichia coli O104:H4 str. 2009EL-2050 type II secretion protein GspC YP_006768508.1 850489 D 1134782 CDS YP_006768509.1 410480963 13691393 851478..853538 1 NC_018650.1 COG1450 Type II secretory pathway, component PulD; general secretion pathway protein D 853538 13691393 O3M_04150 Escherichia coli O104:H4 str. 2009EL-2050 general secretion pathway protein D YP_006768509.1 851478 D 1134782 CDS YP_006768510.1 410480964 13691394 853538..855031 1 NC_018650.1 COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; general secretion pathway protein E 855031 13691394 O3M_04155 Escherichia coli O104:H4 str. 2009EL-2050 general secretion pathway protein E YP_006768510.1 853538 D 1134782 CDS YP_006768511.1 410480965 13691395 855031..856254 1 NC_018650.1 COG1459 Type II secretory pathway, component PulF; General secretion pathway protein F 856254 13691395 O3M_04160 Escherichia coli O104:H4 str. 2009EL-2050 General secretion pathway protein F YP_006768511.1 855031 D 1134782 CDS YP_006768512.1 410480966 13691396 856271..856726 1 NC_018650.1 COG2165 Type II secretory pathway, pseudopilin PulG; general secretion pathway protein G 856726 13691396 O3M_04165 Escherichia coli O104:H4 str. 2009EL-2050 general secretion pathway protein G YP_006768512.1 856271 D 1134782 CDS YP_006768513.1 410480967 13691397 856730..857293 1 NC_018650.1 COG2165 Type II secretory pathway, pseudopilin PulG; general secretion pathway protein H 857293 13691397 O3M_04170 Escherichia coli O104:H4 str. 2009EL-2050 general secretion pathway protein H YP_006768513.1 856730 D 1134782 CDS YP_006768514.1 410480968 13691398 857290..857661 1 NC_018650.1 COG2165 Type II secretory pathway, pseudopilin PulG; type II secretion protein 857661 13691398 O3M_04175 Escherichia coli O104:H4 str. 2009EL-2050 type II secretion protein YP_006768514.1 857290 D 1134782 CDS YP_006768515.1 410480969 13691399 857658..858257 1 NC_018650.1 COG4795 Type II secretory pathway, component PulJ; general secretion pathway protein J 858257 13691399 O3M_04180 Escherichia coli O104:H4 str. 2009EL-2050 general secretion pathway protein J YP_006768515.1 857658 D 1134782 CDS YP_006768516.1 410480970 13691400 858260..859237 1 NC_018650.1 COG3156 Type II secretory pathway, component PulK; type II secretion protein (GspK-like) 859237 13691400 O3M_04185 Escherichia coli O104:H4 str. 2009EL-2050 type II secretion protein (GspK-like) YP_006768516.1 858260 D 1134782 CDS YP_006768517.1 410480971 13691401 859234..860412 1 NC_018650.1 COG3297 Type II secretory pathway, component PulL; GspL-like protein 860412 13691401 O3M_04190 Escherichia coli O104:H4 str. 2009EL-2050 GspL-like protein YP_006768517.1 859234 D 1134782 CDS YP_006768518.1 410480972 13691402 860414..860950 1 NC_018650.1 COG3149 Type II secretory pathway, component PulM; general secretion pathway protein YghD 860950 13691402 O3M_04195 Escherichia coli O104:H4 str. 2009EL-2050 general secretion pathway protein YghD YP_006768518.1 860414 D 1134782 CDS YP_006768519.1 410480973 13691403 complement(861231..862073) 1 NC_018650.1 hypothetical protein 862073 13691403 O3M_04200 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768519.1 861231 R 1134782 CDS YP_006768520.1 410480974 13691404 complement(862158..862580) 1 NC_018650.1 hypothetical protein 862580 13691404 O3M_04205 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768520.1 862158 R 1134782 CDS YP_006768521.1 410480975 13691405 complement(862577..862954) 1 NC_018650.1 toxin of the YeeV-YeeU toxin-antitoxin system 862954 13691405 O3M_04210 Escherichia coli O104:H4 str. 2009EL-2050 toxin of the YeeV-YeeU toxin-antitoxin system YP_006768521.1 862577 R 1134782 CDS YP_006768522.1 410480976 13691406 complement(863001..863378) 1 NC_018650.1 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 863378 13691406 O3M_04215 Escherichia coli O104:H4 str. 2009EL-2050 antitoxin of the YeeV-YeeU toxin-antitoxin system YP_006768522.1 863001 R 1134782 CDS YP_006768523.1 410480977 13691407 complement(863458..863679) 1 NC_018650.1 hypothetical protein 863679 13691407 O3M_04220 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768523.1 863458 R 1134782 CDS YP_006768524.1 410480978 13691408 complement(863766..864242) 1 NC_018650.1 CP4-44 prophage; COG2003 DNA repair proteins; DNA repair protein 864242 13691408 O3M_04225 Escherichia coli O104:H4 str. 2009EL-2050 DNA repair protein YP_006768524.1 863766 R 1134782 CDS YP_006768525.1 410480979 13691409 complement(864258..864731) 1 NC_018650.1 hypothetical protein 864731 13691409 O3M_04230 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768525.1 864258 R 1134782 CDS YP_006768526.1 410480980 13691410 complement(865033..865851) 1 NC_018650.1 hypothetical protein 865851 13691410 O3M_04235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768526.1 865033 R 1134782 CDS YP_006768527.1 410480981 13691411 complement(865951..866184) 1 NC_018650.1 hypothetical protein 866184 13691411 O3M_04240 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768527.1 865951 R 1134782 CDS YP_006768528.1 410480982 13691412 complement(866263..866718) 1 NC_018650.1 hypothetical protein 866718 13691412 O3M_04245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768528.1 866263 R 1134782 CDS YP_006768529.1 410480983 13691413 complement(866794..869310) 1 NC_018650.1 membrane protein, yeeR 869310 13691413 O3M_04250 Escherichia coli O104:H4 str. 2009EL-2050 membrane protein, yeeR YP_006768529.1 866794 R 1134782 CDS YP_006768530.1 410480984 13691414 complement(869431..872550) 1 NC_018650.1 COG2931 RTX toxins and related Ca2+-binding proteins; antigen 43 (Ag43) phase-variable biofilm formation autotransporter, CP4-44 prophage 872550 13691414 O3M_04255 Escherichia coli O104:H4 str. 2009EL-2050 antigen 43 (Ag43) phase-variable biofilm formation autotransporter, CP4-44 prophage YP_006768530.1 869431 R 1134782 CDS YP_006768531.1 410480985 13691415 complement(872884..873756) 1 NC_018650.1 COG3596 Predicted GTPase; GTPase 873756 13691415 O3M_04260 Escherichia coli O104:H4 str. 2009EL-2050 GTPase YP_006768531.1 872884 R 1134782 CDS YP_006768532.1 410480986 13691416 complement(873866..874885) 1 NC_018650.1 hypothetical protein 874885 13691416 O3M_04265 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768532.1 873866 R 1134782 CDS YP_006768533.1 410480987 13691417 875866..876054 1 NC_018650.1 hypothetical protein 876054 13691417 O3M_04270 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768533.1 875866 D 1134782 CDS YP_006768534.1 410480988 13691418 complement(876380..876952) 1 NC_018650.1 hypothetical protein 876952 13691418 O3M_04275 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768534.1 876380 R 1134782 CDS YP_006768535.1 410480989 13691419 complement(877038..877244) 1 NC_018650.1 COG3311 Predicted transcriptional regulator; Prophage CP4-57 regulatory protein 877244 13691419 O3M_04280 Escherichia coli O104:H4 str. 2009EL-2050 Prophage CP4-57 regulatory protein YP_006768535.1 877038 R 1134782 CDS YP_006768536.1 410480990 13691420 877943..878155 1 NC_018650.1 hemolysin expression-modulating protein 878155 13691420 O3M_04285 Escherichia coli O104:H4 str. 2009EL-2050 hemolysin expression-modulating protein YP_006768536.1 877943 D 1134782 CDS YP_006768537.1 410480991 13691421 878772..879341 1 NC_018650.1 hypothetical protein 879341 13691421 O3M_04290 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768537.1 878772 D 1134782 CDS YP_006768538.1 410480992 13691422 879509..879892 1 NC_018650.1 hypothetical protein 879892 13691422 O3M_04295 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768538.1 879509 D 1134782 CDS YP_006768539.1 410480993 13691423 879882..880301 1 NC_018650.1 hypothetical protein 880301 13691423 O3M_04300 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768539.1 879882 D 1134782 CDS YP_006768540.1 410480994 13691424 880307..880489 1 NC_018650.1 hypothetical protein 880489 13691424 O3M_04305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768540.1 880307 D 1134782 CDS YP_006768541.1 410480995 13691425 880610..881233 1 NC_018650.1 hypothetical protein 881233 13691425 O3M_04310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768541.1 880610 D 1134782 CDS YP_006768542.1 410480996 13691426 881329..881562 1 NC_018650.1 hypothetical protein 881562 13691426 O3M_04315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768542.1 881329 D 1134782 CDS YP_006768543.1 410480997 13691427 complement(881615..881806) 1 NC_018650.1 hypothetical protein 881806 13691427 O3M_04320 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768543.1 881615 R 1134782 CDS YP_006768544.1 410480998 13691428 882313..882810 1 NC_018650.1 COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 882810 13691428 O3M_04325 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768544.1 882313 D 1134782 CDS YP_006768545.1 410480999 13691429 882832..884193 1 NC_018650.1 COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 884193 13691429 O3M_04330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768545.1 882832 D 1134782 CDS YP_006768546.1 410481000 13691430 884295..885539 1 NC_018650.1 hypothetical protein 885539 13691430 O3M_04335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768546.1 884295 D 1134782 CDS YP_006768547.1 410481001 13691431 885856..887520 1 NC_018650.1 COG0210 Superfamily I DNA and RNA helicases; UvrD/REP helicase 887520 13691431 O3M_04340 Escherichia coli O104:H4 str. 2009EL-2050 UvrD/REP helicase YP_006768547.1 885856 D 1134782 CDS YP_006768548.1 410481002 13691432 887582..887890 1 NC_018650.1 hypothetical protein 887890 13691432 O3M_04345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768548.1 887582 D 1134782 CDS YP_006768549.1 410481003 13691433 887945..888172 1 NC_018650.1 COG1475 Predicted transcriptional regulators; transcriptional regulator IbrB 888172 13691433 O3M_04350 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator IbrB YP_006768549.1 887945 D 1134782 CDS YP_006768550.1 410481004 13691434 888251..888520 1 NC_018650.1 transcriptional regulator 888520 13691434 O3M_04355 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768550.1 888251 D 1134782 CDS YP_006768551.1 410481005 13691435 888541..889185 1 NC_018650.1 hypothetical protein 889185 13691435 O3M_04360 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768551.1 888541 D 1134782 CDS YP_006768552.1 410481006 13691436 889251..889574 1 NC_018650.1 hypothetical protein 889574 13691436 O3M_04365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768552.1 889251 D 1134782 CDS YP_006768553.1 410481007 13691437 complement(889628..890023) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; hypothetical protein 890023 13691437 O3M_04370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768553.1 889628 R 1134782 CDS YP_006768554.1 410481008 13691438 890394..890780 1 NC_018650.1 hypothetical protein 890780 13691438 O3M_04380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768554.1 890394 D 1134782 CDS YP_006768555.1 410481009 13691439 892301..892777 1 NC_018650.1 COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 892777 13691439 O3M_04400 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768555.1 892301 D 1134782 CDS YP_006768556.1 410481010 13691440 892780..894258 1 NC_018650.1 COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 894258 13691440 O3M_04405 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768556.1 892780 D 1134782 CDS YP_006768557.1 410481011 13691441 894268..894774 1 NC_018650.1 hypothetical protein 894774 13691441 O3M_04410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768557.1 894268 D 1134782 CDS YP_006768558.1 410481012 13691442 894784..895206 1 NC_018650.1 hypothetical protein 895206 13691442 O3M_04415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768558.1 894784 D 1134782 CDS YP_006768559.1 410481013 13691443 complement(895242..895538) 1 NC_018650.1 hypothetical protein 895538 13691443 O3M_04420 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768559.1 895242 R 1134782 CDS YP_006768560.1 410481014 13691444 895670..897001 1 NC_018650.1 COG3519 Uncharacterized protein conserved in bacteria; hypothetical protein 897001 13691444 O3M_04425 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768560.1 895670 D 1134782 CDS YP_006768561.1 410481015 13691445 896992..897924 1 NC_018650.1 COG3520 Uncharacterized protein conserved in bacteria; hypothetical protein 897924 13691445 O3M_04430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768561.1 896992 D 1134782 CDS YP_006768562.1 410481016 13691446 897937..899919 1 NC_018650.1 COG3501 Uncharacterized protein conserved in bacteria; hypothetical protein 899919 13691446 O3M_04435 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768562.1 897937 D 1134782 CDS YP_006768563.1 410481017 13691447 899930..900397 1 NC_018650.1 hypothetical protein 900397 13691447 O3M_04440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768563.1 899930 D 1134782 CDS YP_006768564.1 410481018 13691448 900401..900706 1 NC_018650.1 COG4104 Uncharacterized conserved protein; hypothetical protein 900706 13691448 O3M_04445 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768564.1 900401 D 1134782 CDS YP_006768565.1 410481019 13691449 900710..901786 1 NC_018650.1 COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 901786 13691449 O3M_04450 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768565.1 900710 D 1134782 CDS YP_006768566.1 410481020 13691450 901794..902345 1 NC_018650.1 hypothetical protein 902345 13691450 O3M_04455 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768566.1 901794 D 1134782 CDS YP_006768567.1 410481021 13691451 902364..903776 1 NC_018650.1 COG3522 Uncharacterized protein conserved in bacteria; hypothetical protein 903776 13691451 O3M_04460 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768567.1 902364 D 1134782 CDS YP_006768568.1 410481022 13691452 903804..904118 1 NC_018650.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; hypothetical protein 904118 13691452 O3M_04465 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768568.1 903804 D 1134782 CDS YP_006768569.1 410481023 13691453 904115..904705 1 NC_018650.1 COG3455 Uncharacterized protein conserved in bacteria; hypothetical protein 904705 13691453 O3M_04470 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768569.1 904115 D 1134782 CDS YP_006768570.1 410481024 13691454 904702..908115 1 NC_018650.1 COG3523 Uncharacterized protein conserved in bacteria; hypothetical protein 908115 13691454 O3M_04475 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768570.1 904702 D 1134782 CDS YP_006768571.1 410481025 13691455 908119..910668 1 NC_018650.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 910668 13691455 O3M_04480 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768571.1 908119 D 1134782 CDS YP_006768572.1 410481026 13691456 911705..912076 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase 912076 13691456 O3M_04490 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768572.1 911705 D 1134782 CDS YP_006768573.1 410481027 13691457 913834..914400 1 NC_018650.1 hypothetical protein 914400 13691457 O3M_04495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768573.1 913834 D 1134782 CDS YP_006768574.1 410481028 13691458 complement(914545..914778) 1 NC_018650.1 hypothetical protein 914778 13691458 O3M_04500 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768574.1 914545 R 1134782 CDS YP_006768575.1 410481029 13691459 914879..916033 1 NC_018650.1 hypothetical protein 916033 13691459 O3M_04505 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768575.1 914879 D 1134782 CDS YP_006768576.1 410481030 13691460 916424..916825 1 NC_018650.1 hypothetical protein 916825 13691460 O3M_04510 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768576.1 916424 D 1134782 CDS YP_006768577.1 410481031 13691461 complement(917099..917284) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 917284 13691461 O3M_04515 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768577.1 917099 R 1134782 CDS YP_006768578.1 410481032 13691462 917348..918481 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 918481 13691462 O3M_04520 Escherichia coli O104:H4 str. 2009EL-2050 transposase, IS110 family protein YP_006768578.1 917348 D 1134782 CDS YP_006768579.1 410481033 13691463 918620..918883 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; IS150 ORF B; transposase 918883 13691463 O3M_04525 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768579.1 918620 D 1134782 CDS YP_006768580.1 410481034 13691464 complement(919251..920231) 1 NC_018650.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 920231 13691464 O3M_04530 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768580.1 919251 R 1134782 CDS YP_006768581.1 410481035 13691465 complement(920415..920978) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; transposase 920978 13691465 O3M_04535 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768581.1 920415 R 1134782 CDS YP_006768582.1 410481036 13691466 complement(920875..921630) 1 NC_018650.1 COG4584 Transposase and inactivated derivatives; transposase 921630 13691466 O3M_04540 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768582.1 920875 R 1134782 CDS YP_006768583.1 410481037 13691467 complement(921896..922000) 1 NC_018650.1 transposase 922000 13691467 O3M_04545 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768583.1 921896 R 1134782 CDS YP_006768584.1 410481038 13691468 complement(922067..922201) 1 NC_018650.1 hypothetical protein 922201 13691468 O3M_04550 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768584.1 922067 R 1134782 CDS YP_006768585.1 410481039 13691469 922200..922730 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 922730 13691469 O3M_04555 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768585.1 922200 D 1134782 CDS YP_006768586.1 410481040 13691470 922793..923011 1 NC_018650.1 COG3328 Transposase and inactivated derivatives; transposase 923011 13691470 O3M_04560 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768586.1 922793 D 1134782 CDS YP_006768587.1 410481041 13691471 complement(923162..923497) 1 NC_018650.1 Serine protease pic precursor (ShMu) 923497 13691471 O3M_04565 Escherichia coli O104:H4 str. 2009EL-2050 Serine protease pic precursor (ShMu) YP_006768587.1 923162 R 1134782 CDS YP_006768588.1 410481042 13691472 complement(923499..927281) 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; Serine protease pic precursor (ShMu) 927281 13691472 O3M_04570 Escherichia coli O104:H4 str. 2009EL-2050 Serine protease pic precursor (ShMu) YP_006768588.1 923499 R 1134782 CDS YP_006768589.1 410481043 13691473 complement(927446..927817) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase 927817 13691473 O3M_04575 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006768589.1 927446 R 1134782 CDS YP_006768590.1 410481044 13691474 complement(928009..929532) 1 NC_018650.1 COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid 929532 13691474 O3M_04580 Escherichia coli O104:H4 str. 2009EL-2050 reverse transcriptase-like protein from prophage or plasmid YP_006768590.1 928009 R 1134782 CDS YP_006768591.1 410481045 13691475 complement(930124..930363) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; hypothetical protein 930363 13691475 O3M_04585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768591.1 930124 R 1134782 CDS YP_006768592.1 410481046 13691476 930680..931831 1 NC_018650.1 COG2826 Transposase and inactivated derivatives, IS30 family; transposase for IS30 931831 13691476 O3M_04590 Escherichia coli O104:H4 str. 2009EL-2050 transposase for IS30 YP_006768592.1 930680 D 1134782 CDS YP_006768593.1 410481047 13691477 complement(931751..932137) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS3 family protein; transposase ORF A, IS3 family protein 932137 13691477 O3M_04595 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS3 family protein YP_006768593.1 931751 R 1134782 CDS YP_006768594.1 410481048 13691478 complement(932171..932464) 1 NC_018650.1 hypothetical protein 932464 13691478 O3M_04600 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768594.1 932171 R 1134782 CDS YP_006768595.1 410481049 13691479 complement(932553..935423) 1 NC_018650.1 COG3421 Uncharacterized protein conserved in bacteria; PstII restriction-modification enzyme Res subunit 935423 13691479 O3M_04605 Escherichia coli O104:H4 str. 2009EL-2050 PstII restriction-modification enzyme Res subunit YP_006768595.1 932553 R 1134782 CDS YP_006768596.1 410481050 13691480 complement(935426..937054) 1 NC_018650.1 COG2189 Adenine specific DNA methylase Mod; DNA methylase N-4/N-6 937054 13691480 O3M_04610 Escherichia coli O104:H4 str. 2009EL-2050 DNA methylase N-4/N-6 YP_006768596.1 935426 R 1134782 CDS YP_006768597.1 410481051 13691481 complement(937064..939451) 1 NC_018650.1 COG1404 Subtilisin-like serine proteases; serine protease 939451 13691481 O3M_04615 Escherichia coli O104:H4 str. 2009EL-2050 serine protease YP_006768597.1 937064 R 1134782 CDS YP_006768598.1 410481052 13691482 complement(939461..940441) 1 NC_018650.1 COG0464 ATPases of the AAA+ class; ATPase 940441 13691482 O3M_04620 Escherichia coli O104:H4 str. 2009EL-2050 ATPase YP_006768598.1 939461 R 1134782 CDS YP_006768599.1 410481053 13691483 complement(940467..943316) 1 NC_018650.1 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Helicase 943316 13691483 O3M_04625 Escherichia coli O104:H4 str. 2009EL-2050 Helicase YP_006768599.1 940467 R 1134782 CDS YP_006768600.1 410481054 13691484 943635..943799 1 NC_018650.1 hypothetical protein 943799 13691484 O3M_04630 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768600.1 943635 D 1134782 CDS YP_006768601.1 410481055 13691485 943727..944320 1 NC_018650.1 hypothetical protein 944320 13691485 O3M_04635 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768601.1 943727 D 1134782 CDS YP_006768602.1 410481056 13691486 complement(944786..945049) 1 NC_018650.1 hypothetical protein 945049 13691486 O3M_04640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768602.1 944786 R 1134782 CDS YP_006768603.1 410481057 13691487 complement(945233..945694) 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 945694 13691487 O3M_04645 Escherichia coli O104:H4 str. 2009EL-2050 IS1 transposase InsAB' YP_006768603.1 945233 R 1134782 CDS YP_006768604.1 410481058 13691488 complement(945613..945888) 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA 945888 13691488 O3M_04650 Escherichia coli O104:H4 str. 2009EL-2050 IS1 repressor protein InsA YP_006768604.1 945613 R 1134782 CDS YP_006768605.1 410481059 13691489 complement(946301..947563) 1 NC_018650.1 COG0582 Integrase; Prophage integrase 947563 13691489 O3M_04655 Escherichia coli O104:H4 str. 2009EL-2050 Prophage integrase YP_006768605.1 946301 R 1134782 CDS YP_006768606.1 410481060 13691491 complement(947942..948649) 1 NC_018650.1 COG1811 Uncharacterized membrane protein, possible Na+ channel or pump; hypothetical protein 948649 13691491 O3M_04660 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768606.1 947942 R 1134782 CDS YP_006768607.1 410481061 13691492 949047..951182 1 NC_018650.1 COG1982 Arginine/lysine/ornithine decarboxylases; ornithine decarboxylase 951182 13691492 O3M_04665 Escherichia coli O104:H4 str. 2009EL-2050 ornithine decarboxylase YP_006768607.1 949047 D 1134782 CDS YP_006768608.1 410481062 13691493 complement(951232..952488) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; nucleoside transport, permease 952488 13691493 O3M_04670 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside transport, permease YP_006768608.1 951232 R 1134782 CDS YP_006768609.1 410481063 13691494 complement(952690..953769) 1 NC_018650.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); murein transglycosylase C 953769 mltC 13691494 mltC Escherichia coli O104:H4 str. 2009EL-2050 murein transglycosylase C YP_006768609.1 952690 R 1134782 CDS YP_006768610.1 410481064 13691495 complement(953834..954109) 1 NC_018650.1 COG2924 Fe-S cluster protector protein; oxidative damage protection protein 954109 13691495 O3M_04680 Escherichia coli O104:H4 str. 2009EL-2050 oxidative damage protection protein YP_006768610.1 953834 R 1134782 CDS YP_006768611.1 410481065 13691496 complement(954137..955189) 1 NC_018650.1 COG1194 A/G-specific DNA glycosylase; adenine DNA glycosylase 955189 13691496 O3M_04685 Escherichia coli O104:H4 str. 2009EL-2050 adenine DNA glycosylase YP_006768611.1 954137 R 1134782 CDS YP_006768612.1 410481066 13691497 955350..956069 1 NC_018650.1 COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; tRNA (guanine-N(7)-)-methyltransferase 956069 trmB 13691497 trmB Escherichia coli O104:H4 str. 2009EL-2050 tRNA (guanine-N(7)-)-methyltransferase YP_006768612.1 955350 D 1134782 CDS YP_006768613.1 410481067 13691498 956069..956395 1 NC_018650.1 COG3171 Uncharacterized protein conserved in bacteria; hypothetical protein 956395 13691498 O3M_04695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768613.1 956069 D 1134782 CDS YP_006768614.1 410481068 13691499 956418..956558 1 NC_018650.1 hypothetical protein 956558 13691499 O3M_04700 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768614.1 956418 D 1134782 CDS YP_006768615.1 410481069 13691500 956579..957298 1 NC_018650.1 hypothetical protein 957298 13691500 O3M_04705 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768615.1 956579 D 1134782 CDS YP_006768616.1 410481070 13691501 957474..958520 1 NC_018650.1 COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; L-asparaginase II 958520 ansB 13691501 ansB Escherichia coli O104:H4 str. 2009EL-2050 L-asparaginase II YP_006768616.1 957474 D 1134782 CDS YP_006768617.1 410481071 13691502 958637..959644 1 NC_018650.1 hypothetical protein 959644 13691502 O3M_04715 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768617.1 958637 D 1134782 CDS YP_006768618.1 410481072 13691503 complement(959799..960935) 1 NC_018650.1 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; HemN family oxidoreductase 960935 13691503 O3M_04720 Escherichia coli O104:H4 str. 2009EL-2050 HemN family oxidoreductase YP_006768618.1 959799 R 1134782 CDS YP_006768619.1 410481073 13691504 complement(960928..961521) 1 NC_018650.1 COG0127 Xanthosine triphosphate pyrophosphatase; dITP/XTP pyrophosphatase 961521 13691504 O3M_04725 Escherichia coli O104:H4 str. 2009EL-2050 dITP/XTP pyrophosphatase YP_006768619.1 960928 R 1134782 CDS YP_006768620.1 410481074 13691505 complement(961529..961819) 1 NC_018650.1 COG1872 Uncharacterized conserved protein; hypothetical protein 961819 13691505 O3M_04730 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768620.1 961529 R 1134782 CDS YP_006768621.1 410481075 13691506 complement(961816..962382) 1 NC_018650.1 COG0762 Predicted integral membrane protein; hypothetical protein 962382 13691506 O3M_04735 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768621.1 961816 R 1134782 CDS YP_006768622.1 410481076 13691507 complement(962400..963104) 1 NC_018650.1 COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein 963104 13691507 O3M_04740 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768622.1 962400 R 1134782 CDS YP_006768623.1 410481077 13691508 963122..964102 1 NC_018650.1 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT; transporter 964102 13691508 O3M_04745 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768623.1 963122 D 1134782 CDS YP_006768624.1 410481078 13691509 complement(964278..964694) 1 NC_018650.1 COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); Holliday junction resolvase-like protein 964694 13691509 O3M_04750 Escherichia coli O104:H4 str. 2009EL-2050 Holliday junction resolvase-like protein YP_006768624.1 964278 R 1134782 CDS YP_006768625.1 410481079 13691510 complement(964694..965257) 1 NC_018650.1 COG1678 Putative transcriptional regulator; hypothetical protein 965257 13691510 O3M_04755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768625.1 964694 R 1134782 CDS YP_006768626.1 410481080 13691511 complement(965366..966316) 1 NC_018650.1 COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); glutathione synthetase 966316 13691511 O3M_04760 Escherichia coli O104:H4 str. 2009EL-2050 glutathione synthetase YP_006768626.1 965366 R 1134782 CDS YP_006768627.1 410481081 13691512 complement(966329..967060) 1 NC_018650.1 COG1385 Uncharacterized protein conserved in bacteria; 16S ribosomal RNA methyltransferase RsmE 967060 13691512 O3M_04765 Escherichia coli O104:H4 str. 2009EL-2050 16S ribosomal RNA methyltransferase RsmE YP_006768627.1 966329 R 1134782 CDS YP_006768628.1 410481082 13691513 complement(967140..967847) 1 NC_018650.1 COG2356 Endonuclease I; DNA-specific endonuclease I 967847 13691513 O3M_04770 Escherichia coli O104:H4 str. 2009EL-2050 DNA-specific endonuclease I YP_006768628.1 967140 R 1134782 CDS YP_006768629.1 410481083 13691595 complement(967942..968439) 1 NC_018650.1 COG3091 Uncharacterized protein conserved in bacteria; hypothetical protein 968439 13691595 O3M_04775 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768629.1 967942 R 1134782 CDS YP_006768630.1 410481084 13691596 complement(968516..969910) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; D-galactose transporter GalP 969910 13691596 O3M_04780 Escherichia coli O104:H4 str. 2009EL-2050 D-galactose transporter GalP YP_006768630.1 968516 R 1134782 CDS YP_006768631.1 410481085 13691597 complement(970346..971500) 1 NC_018650.1 COG0192 S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 971500 13691597 O3M_04785 Escherichia coli O104:H4 str. 2009EL-2050 S-adenosylmethionine synthetase YP_006768631.1 970346 R 1134782 CDS YP_006768632.1 410481086 13691598 971556..971807 1 NC_018650.1 hypothetical protein 971807 13691598 O3M_04790 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768632.1 971556 D 1134782 CDS YP_006768633.1 410481087 13691599 972140..972286 1 NC_018650.1 hypothetical protein 972286 13691599 O3M_04795 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768633.1 972140 D 1134782 CDS YP_006768634.1 410481088 13691600 972295..974271 1 NC_018650.1 COG1166 Arginine decarboxylase (spermidine biosynthesis); arginine decarboxylase 974271 13691600 O3M_04800 Escherichia coli O104:H4 str. 2009EL-2050 arginine decarboxylase YP_006768634.1 972295 D 1134782 CDS YP_006768635.1 410481089 13691601 974417..975148 1 NC_018650.1 hypothetical protein 975148 13691601 O3M_04805 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768635.1 974417 D 1134782 CDS YP_006768636.1 410481090 13691602 975284..976204 1 NC_018650.1 COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; agmatinase 976204 13691602 O3M_04810 Escherichia coli O104:H4 str. 2009EL-2050 agmatinase YP_006768636.1 975284 D 1134782 CDS YP_006768637.1 410481091 13691603 complement(976410..977168) 1 NC_018650.1 COG0501 Zn-dependent protease with chaperone function; peptidase 977168 13691603 O3M_04815 Escherichia coli O104:H4 str. 2009EL-2050 peptidase YP_006768637.1 976410 R 1134782 CDS YP_006768638.1 410481092 13691604 977446..979437 1 NC_018650.1 COG0021 Transketolase; transketolase 979437 13691604 O3M_04820 Escherichia coli O104:H4 str. 2009EL-2050 transketolase YP_006768638.1 977446 D 1134782 CDS YP_006768639.1 410481093 13691605 979751..980194 1 NC_018650.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol-specific transporter subunit IIA 980194 cmtB 13691605 cmtB Escherichia coli O104:H4 str. 2009EL-2050 PTS system mannitol-specific transporter subunit IIA YP_006768639.1 979751 D 1134782 CDS YP_006768640.1 410481094 13691606 980222..981610 1 NC_018650.1 COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system mannitol-specific transporter subunit IIBC 981610 13691606 O3M_04830 Escherichia coli O104:H4 str. 2009EL-2050 PTS system mannitol-specific transporter subunit IIBC YP_006768640.1 980222 D 1134782 CDS YP_006768641.1 410481095 13691607 981625..982902 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; dehydrogenase 982902 13691607 O3M_04835 Escherichia coli O104:H4 str. 2009EL-2050 dehydrogenase YP_006768641.1 981625 D 1134782 CDS YP_006768642.1 410481096 13691608 982899..983864 1 NC_018650.1 COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; fructose-1,6-bisphosphatase II-like protein 983864 13691608 O3M_04840 Escherichia coli O104:H4 str. 2009EL-2050 fructose-1,6-bisphosphatase II-like protein YP_006768642.1 982899 D 1134782 CDS YP_006768643.1 410481097 13691609 983886..984395 1 NC_018650.1 COG3722 Transcriptional regulator; DNA-binding transcriptional regulator 984395 13691609 O3M_04845 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768643.1 983886 D 1134782 CDS YP_006768644.1 410481098 13691610 984392..985105 1 NC_018650.1 COG1072 Panthothenate kinase; nucleoside triphosphate hydrolase domain-containing protein 985105 13691610 O3M_04850 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside triphosphate hydrolase domain-containing protein YP_006768644.1 984392 D 1134782 CDS YP_006768645.1 410481099 13691611 complement(985077..985754) 1 NC_018650.1 COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; ABC transporter ATP-binding protein 985754 13691611 O3M_04855 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006768645.1 985077 R 1134782 CDS YP_006768646.1 410481100 13691612 complement(985748..986425) 1 NC_018650.1 COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein 986425 13691612 O3M_04860 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006768646.1 985748 R 1134782 CDS YP_006768647.1 410481101 13691613 complement(986413..987120) 1 NC_018650.1 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; lipoprotein 987120 13691613 O3M_04865 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006768647.1 986413 R 1134782 CDS YP_006768648.1 410481102 13691614 complement(987121..987699) 1 NC_018650.1 transporter 987699 13691614 O3M_04870 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768648.1 987121 R 1134782 CDS YP_006768649.1 410481103 13691615 complement(987722..988153) 1 NC_018650.1 COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif; DNA-binding protein 988153 13691615 O3M_04875 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding protein YP_006768649.1 987722 R 1134782 CDS YP_006768650.1 410481104 13691616 988525..989544 1 NC_018650.1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; erythrose 4-phosphate dehydrogenase 989544 13691616 O3M_04880 Escherichia coli O104:H4 str. 2009EL-2050 erythrose 4-phosphate dehydrogenase YP_006768650.1 988525 D 1134782 CDS YP_006768651.1 410481105 13691617 989594..990757 1 NC_018650.1 COG0126 3-phosphoglycerate kinase; phosphoglycerate kinase 990757 pgk 13691617 pgk Escherichia coli O104:H4 str. 2009EL-2050 phosphoglycerate kinase YP_006768651.1 989594 D 1134782 CDS YP_006768652.1 410481106 13691618 990972..992051 1 NC_018650.1 COG0191 Fructose/tagatose bisphosphate aldolase; fructose-bisphosphate aldolase 992051 13691618 O3M_04890 Escherichia coli O104:H4 str. 2009EL-2050 fructose-bisphosphate aldolase YP_006768652.1 990972 D 1134782 CDS YP_006768653.1 410481107 13691619 992409..993269 1 NC_018650.1 COG0668 Small-conductance mechanosensitive channel; mechanosensitive channel MscS 993269 13691619 O3M_04895 Escherichia coli O104:H4 str. 2009EL-2050 mechanosensitive channel MscS YP_006768653.1 992409 D 1134782 CDS YP_006768654.1 410481108 13691620 993408..994043 1 NC_018650.1 COG1279 Lysine efflux permease; arginine exporter protein 994043 13691620 O3M_04900 Escherichia coli O104:H4 str. 2009EL-2050 arginine exporter protein YP_006768654.1 993408 D 1134782 CDS YP_006768655.1 410481109 13691621 994136..994876 1 NC_018650.1 COG2968 Uncharacterized conserved protein; oxidative stress defense protein 994876 13691621 O3M_04905 Escherichia coli O104:H4 str. 2009EL-2050 oxidative stress defense protein YP_006768655.1 994136 D 1134782 CDS YP_006768656.1 410481110 13691622 995043..995939 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 995939 13691622 O3M_04910 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768656.1 995043 D 1134782 CDS YP_006768657.1 410481111 13691623 complement(995936..997414) 1 NC_018650.1 COG0427 Acetyl-CoA hydrolase; acetyl-CoA hydrolase 997414 13691623 O3M_04915 Escherichia coli O104:H4 str. 2009EL-2050 acetyl-CoA hydrolase YP_006768657.1 995936 R 1134782 CDS YP_006768658.1 410481112 13691624 complement(997438..998223) 1 NC_018650.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; methylmalonyl-CoA decarboxylase 998223 13691624 O3M_04920 Escherichia coli O104:H4 str. 2009EL-2050 methylmalonyl-CoA decarboxylase YP_006768658.1 997438 R 1134782 CDS YP_006768659.1 410481113 13691625 complement(998234..999229) 1 NC_018650.1 COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family; membrane ATPase/protein kinase 999229 13691625 O3M_04925 Escherichia coli O104:H4 str. 2009EL-2050 membrane ATPase/protein kinase YP_006768659.1 998234 R 1134782 CDS YP_006768660.1 410481114 13691626 complement(999222..1000514) 1 NC_018650.1 COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; methylmalonyl-CoA mutase 1000514 13691626 O3M_04930 Escherichia coli O104:H4 str. 2009EL-2050 methylmalonyl-CoA mutase YP_006768660.1 999222 R 1134782 CDS YP_006768661.1 410481115 13691627 complement(1000638..1001366) 1 NC_018650.1 COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; methylmalonyl-CoA mutase 1001366 13691627 O3M_04935 Escherichia coli O104:H4 str. 2009EL-2050 methylmalonyl-CoA mutase YP_006768661.1 1000638 R 1134782 CDS YP_006768662.1 410481116 13691628 complement(1001570..1002463) 1 NC_018650.1 COG0583 Transcriptional regulator; chromosome replication initiation inhibitor protein 1002463 13691628 O3M_04940 Escherichia coli O104:H4 str. 2009EL-2050 chromosome replication initiation inhibitor protein YP_006768662.1 1001570 R 1134782 CDS YP_006768663.1 410481117 13691629 1002846..1003505 1 NC_018650.1 COG0120 Ribose 5-phosphate isomerase; ribose-5-phosphate isomerase A 1003505 13691629 O3M_04945 Escherichia coli O104:H4 str. 2009EL-2050 ribose-5-phosphate isomerase A YP_006768663.1 1002846 D 1134782 CDS YP_006768664.1 410481118 13691630 1003761..1004993 1 NC_018650.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; D-3-phosphoglycerate dehydrogenase 1004993 13691630 O3M_04950 Escherichia coli O104:H4 str. 2009EL-2050 D-3-phosphoglycerate dehydrogenase YP_006768664.1 1003761 D 1134782 CDS YP_006768665.1 410481119 13691631 complement(1005774..1006322) 1 NC_018650.1 COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 1006322 13691631 O3M_04955 Escherichia coli O104:H4 str. 2009EL-2050 5-formyltetrahydrofolate cyclo-ligase YP_006768665.1 1005774 R 1134782 CDS YP_006768666.1 410481120 13691632 complement(1006622..1006951) 1 NC_018650.1 COG3027 Uncharacterized protein conserved in bacteria; Z-ring-associated protein 1006951 13691632 O3M_04960 Escherichia coli O104:H4 str. 2009EL-2050 Z-ring-associated protein YP_006768666.1 1006622 R 1134782 CDS YP_006768667.1 410481121 13691633 1007119..1007697 1 NC_018650.1 COG3079 Uncharacterized protein conserved in bacteria; hypothetical protein 1007697 13691633 O3M_04965 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768667.1 1007119 D 1134782 CDS YP_006768668.1 410481122 13691634 1007723..1009048 1 NC_018650.1 COG0006 Xaa-Pro aminopeptidase; proline aminopeptidase P II 1009048 13691634 O3M_04970 Escherichia coli O104:H4 str. 2009EL-2050 proline aminopeptidase P II YP_006768668.1 1007723 D 1134782 CDS YP_006768669.1 410481123 13691635 1009045..1010223 1 NC_018650.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 2-octaprenyl-6-methoxyphenyl hydroxylase 1010223 13691635 O3M_04975 Escherichia coli O104:H4 str. 2009EL-2050 2-octaprenyl-6-methoxyphenyl hydroxylase YP_006768669.1 1009045 D 1134782 CDS YP_006768670.1 410481124 13691636 1010246..1011448 1 NC_018650.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; oxidoreductase 1011448 13691636 O3M_04980 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006768670.1 1010246 D 1134782 CDS YP_006768671.1 410481125 13691637 1011896..1012990 1 NC_018650.1 COG0404 Glycine cleavage system T protein (aminomethyltransferase); glycine cleavage system aminomethyltransferase T 1012990 gcvT 13691637 gcvT Escherichia coli O104:H4 str. 2009EL-2050 glycine cleavage system aminomethyltransferase T YP_006768671.1 1011896 D 1134782 CDS YP_006768672.1 410481126 13691638 1013014..1013403 1 NC_018650.1 COG0509 Glycine cleavage system H protein (lipoate-binding); glycine cleavage system protein H 1013403 13691638 O3M_04990 Escherichia coli O104:H4 str. 2009EL-2050 glycine cleavage system protein H YP_006768672.1 1013014 D 1134782 CDS YP_006768673.1 410481127 13691639 1013522..1016395 1 NC_018650.1 COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; glycine dehydrogenase 1016395 13691639 O3M_04995 Escherichia coli O104:H4 str. 2009EL-2050 glycine dehydrogenase YP_006768673.1 1013522 D 1134782 CDS YP_006768674.1 410481128 13691640 1016656..1017399 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); NAD(P)-binding oxidoreductase 1017399 13691640 O3M_05000 Escherichia coli O104:H4 str. 2009EL-2050 NAD(P)-binding oxidoreductase YP_006768674.1 1016656 D 1134782 CDS YP_006768675.1 410481129 13691641 complement(1017456..1018889) 1 NC_018650.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; 6-phospho-beta-glucosidase 1018889 13691641 O3M_05005 Escherichia coli O104:H4 str. 2009EL-2050 6-phospho-beta-glucosidase YP_006768675.1 1017456 R 1134782 CDS YP_006768676.1 410481130 13691642 1018934..1019245 1 NC_018650.1 COG3097 Uncharacterized protein conserved in bacteria; hypothetical protein 1019245 13691642 O3M_05010 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768676.1 1018934 D 1134782 CDS YP_006768677.1 410481131 13691643 1019409..1020068 1 NC_018650.1 COG1272 Predicted membrane protein, hemolysin III homolog; hemolysin 1020068 13691643 O3M_05015 Escherichia coli O104:H4 str. 2009EL-2050 hemolysin YP_006768677.1 1019409 D 1134782 CDS YP_006768678.1 410481132 13691644 complement(1020146..1021126) 1 NC_018650.1 COG0354 Predicted aminomethyltransferase related to GcvT; global regulator 1021126 13691644 O3M_05020 Escherichia coli O104:H4 str. 2009EL-2050 global regulator YP_006768678.1 1020146 R 1134782 CDS YP_006768679.1 410481133 13691645 1021369..1021635 1 NC_018650.1 COG2938 Uncharacterized conserved protein; hypothetical protein 1021635 13691645 O3M_05025 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768679.1 1021369 D 1134782 CDS YP_006768680.1 410481134 13691646 1021616..1022023 1 NC_018650.1 hypothetical protein 1022023 13691646 O3M_05030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768680.1 1021616 D 1134782 CDS YP_006768681.1 410481135 13691647 complement(1022063..1022584) 1 NC_018650.1 COG0716 Flavodoxins; flavodoxin FldB 1022584 13691647 O3M_05035 Escherichia coli O104:H4 str. 2009EL-2050 flavodoxin FldB YP_006768681.1 1022063 R 1134782 CDS YP_006768682.1 410481136 13691648 1022696..1023592 1 NC_018650.1 COG4974 Site-specific recombinase XerD; site-specific tyrosine recombinase XerD 1023592 xerD 13691648 xerD Escherichia coli O104:H4 str. 2009EL-2050 site-specific tyrosine recombinase XerD YP_006768682.1 1022696 D 1134782 CDS YP_006768683.1 410481137 13691649 1023617..1024327 1 NC_018650.1 COG1651 Protein-disulfide isomerase; protein disulfide isomerase II DsbC 1024327 13691649 O3M_05045 Escherichia coli O104:H4 str. 2009EL-2050 protein disulfide isomerase II DsbC YP_006768683.1 1023617 D 1134782 CDS YP_006768684.1 410481138 13691650 1024333..1026066 1 NC_018650.1 COG0608 Single-stranded DNA-specific exonuclease; ssDNA exonuclease RecJ 1026066 13691650 O3M_05050 Escherichia coli O104:H4 str. 2009EL-2050 ssDNA exonuclease RecJ YP_006768684.1 1024333 D 1134782 CDS YP_006768685.1 410481139 13691651 1026374..1027255 1 NC_018650.1 COG1186 Protein chain release factor B; peptide chain release factor 2 1027255 prfB 13691651 prfB Escherichia coli O104:H4 str. 2009EL-2050 peptide chain release factor 2 YP_006768685.1 1026374 D 1134782 CDS YP_006768686.1 410481140 13691652 1027265..1028782 1 NC_018650.1 COG1190 Lysyl-tRNA synthetase (class II); lysyl-tRNA synthetase 1028782 lysS 13691652 lysS Escherichia coli O104:H4 str. 2009EL-2050 lysyl-tRNA synthetase YP_006768686.1 1027265 D 1134782 CDS YP_006768687.1 410481141 13691653 complement(1028825..1029373) 1 NC_018650.1 COG1443 Isopentenyldiphosphate isomerase; isopentenyl-diphosphate delta-isomerase 1029373 13691653 O3M_05065 Escherichia coli O104:H4 str. 2009EL-2050 isopentenyl-diphosphate delta-isomerase YP_006768687.1 1028825 R 1134782 CDS YP_006768688.1 410481142 13691654 complement(1029496..1029621) 1 NC_018650.1 hypothetical protein 1029621 13691654 O3M_05070 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768688.1 1029496 R 1134782 CDS YP_006768689.1 410481143 13691655 complement(1029623..1031071) 1 NC_018650.1 COG2233 Xanthine/uracil permeases; transporter 1031071 13691655 O3M_05075 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768689.1 1029623 R 1134782 CDS YP_006768690.1 410481144 13691656 1031507..1033426 1 NC_018650.1 COG1142 Fe-S-cluster-containing hydrogenase components 2; oxidoreductase Fe-S binding subunit 1033426 13691656 O3M_05080 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase Fe-S binding subunit YP_006768690.1 1031507 D 1134782 CDS YP_006768691.1 410481145 13691657 1033426..1033914 1 NC_018650.1 COG1142 Fe-S-cluster-containing hydrogenase components 2; oxidoreductase 1033914 13691657 O3M_05085 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006768691.1 1033426 D 1134782 CDS YP_006768692.1 410481146 13691658 complement(1033950..1035317) 1 NC_018650.1 COG2252 Permeases; hypothetical protein 1035317 13691658 O3M_05090 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768692.1 1033950 R 1134782 CDS YP_006768693.1 410481147 13691659 complement(1035353..1036669) 1 NC_018650.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; guanine deaminase 1036669 13691659 O3M_05095 Escherichia coli O104:H4 str. 2009EL-2050 guanine deaminase YP_006768693.1 1035353 R 1134782 CDS YP_006768694.1 410481148 13691660 complement(1036687..1038087) 1 NC_018650.1 COG2233 Xanthine/uracil permeases; transporter 1038087 13691660 O3M_05100 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768694.1 1036687 R 1134782 CDS YP_006768695.1 410481149 13691661 complement(1038252..1041122) 1 NC_018650.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; hypoxanthine oxidase 1041122 13691661 O3M_05105 Escherichia coli O104:H4 str. 2009EL-2050 hypoxanthine oxidase YP_006768695.1 1038252 R 1134782 CDS YP_006768696.1 410481150 13691662 complement(1041119..1041898) 1 NC_018650.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; oxidoreductase 1041898 13691662 O3M_05110 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006768696.1 1041119 R 1134782 CDS YP_006768697.1 410481151 13691663 complement(1041949..1043277) 1 NC_018650.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; chlorohydrolase/aminohydrolase 1043277 13691663 O3M_05115 Escherichia coli O104:H4 str. 2009EL-2050 chlorohydrolase/aminohydrolase YP_006768697.1 1041949 R 1134782 CDS YP_006768698.1 410481152 13691664 complement(1043280..1046378) 1 NC_018650.1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; selenate reductase subunit YgfK 1046378 13691664 O3M_05120 Escherichia coli O104:H4 str. 2009EL-2050 selenate reductase subunit YgfK YP_006768698.1 1043280 R 1134782 CDS YP_006768699.1 410481153 13691665 complement(1046700..1047278) 1 NC_018650.1 COG2068 Uncharacterized MobA-related protein; hypothetical protein 1047278 13691665 O3M_05125 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768699.1 1046700 R 1134782 CDS YP_006768700.1 410481154 13691666 1047381..1048151 1 NC_018650.1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; hypothetical protein 1048151 13691666 O3M_05130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768700.1 1047381 D 1134782 CDS YP_006768701.1 410481155 13691667 1048199..1049824 1 NC_018650.1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 1049824 13691667 O3M_05135 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768701.1 1048199 D 1134782 CDS YP_006768702.1 410481156 13691668 complement(1049865..1050797) 1 NC_018650.1 COG0549 Carbamate kinase; amino acid kinase 1050797 13691668 O3M_05140 Escherichia coli O104:H4 str. 2009EL-2050 amino acid kinase YP_006768702.1 1049865 R 1134782 CDS YP_006768703.1 410481157 13691669 complement(1050845..1052230) 1 NC_018650.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; phenylhydantoinase 1052230 13691669 O3M_05145 Escherichia coli O104:H4 str. 2009EL-2050 phenylhydantoinase YP_006768703.1 1050845 R 1134782 CDS YP_006768704.1 410481158 13691670 complement(1052283..1053494) 1 NC_018650.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; peptidase 1053494 13691670 O3M_05150 Escherichia coli O104:H4 str. 2009EL-2050 peptidase YP_006768704.1 1052283 R 1134782 CDS YP_006768705.1 410481159 13691671 complement(1053552..1054748) 1 NC_018650.1 COG1171 Threonine dehydratase; diaminopropionate ammonia-lyase 1054748 13691671 O3M_05155 Escherichia coli O104:H4 str. 2009EL-2050 diaminopropionate ammonia-lyase YP_006768705.1 1053552 R 1134782 CDS YP_006768706.1 410481160 13691672 complement(1054806..1055993) 1 NC_018650.1 COG0078 Ornithine carbamoyltransferase; aspartate/ornithine carbamoyltransferase family protein 1055993 13691672 O3M_05160 Escherichia coli O104:H4 str. 2009EL-2050 aspartate/ornithine carbamoyltransferase family protein YP_006768706.1 1054806 R 1134782 CDS YP_006768707.1 410481161 13691673 1056472..1058250 1 NC_018650.1 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains; DNA-binding transcriptional regulator 1058250 13691673 O3M_05165 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768707.1 1056472 D 1134782 CDS YP_006768708.1 410481162 13691674 complement(1058290..1058769) 1 NC_018650.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; xanthine dehydrogenase subunit XdhC 1058769 13691674 O3M_05170 Escherichia coli O104:H4 str. 2009EL-2050 xanthine dehydrogenase subunit XdhC YP_006768708.1 1058290 R 1134782 CDS YP_006768709.1 410481163 13691675 complement(1058766..1059644) 1 NC_018650.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; xanthine dehydrogenase subunit XdhB 1059644 13691675 O3M_05175 Escherichia coli O104:H4 str. 2009EL-2050 xanthine dehydrogenase subunit XdhB YP_006768709.1 1058766 R 1134782 CDS YP_006768710.1 410481164 13691757 complement(1059655..1061952) 1 NC_018650.1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; xanthine dehydrogenase subunit XdhA 1061952 13691757 O3M_05180 Escherichia coli O104:H4 str. 2009EL-2050 xanthine dehydrogenase subunit XdhA YP_006768710.1 1059655 R 1134782 CDS YP_006768711.1 410481165 13691758 1062367..1063122 1 NC_018650.1 COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 1063122 13691758 O3M_05185 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768711.1 1062367 D 1134782 CDS YP_006768712.1 410481166 13691760 1063466..1065118 1 NC_018650.1 hypothetical protein 1065118 13691760 O3M_05190 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768712.1 1063466 D 1134782 CDS YP_006768713.1 410481167 13691761 1066187..1066852 1 NC_018650.1 COG4790 Type III secretory pathway, component EscR; type III secretion system protein SpaP 1066852 spaP 13691761 spaP Escherichia coli O104:H4 str. 2009EL-2050 type III secretion system protein SpaP YP_006768713.1 1066187 D 1134782 CDS YP_006768714.1 410481168 13691762 1066862..1067122 1 NC_018650.1 COG4794 Type III secretory pathway, component EscS; type III secretion protein EpaQ 1067122 13691762 O3M_05210 Escherichia coli O104:H4 str. 2009EL-2050 type III secretion protein EpaQ YP_006768714.1 1066862 D 1134782 CDS YP_006768715.1 410481169 13691763 1067124..1067891 1 NC_018650.1 COG4791 Type III secretory pathway, component EscT; type III secretion apparatus protein SpaR/YscT/HrcT 1067891 13691763 O3M_05215 Escherichia coli O104:H4 str. 2009EL-2050 type III secretion apparatus protein SpaR/YscT/HrcT YP_006768715.1 1067124 D 1134782 CDS YP_006768716.1 410481170 13691764 1068706..1069068 1 NC_018650.1 COG1377 Flagellar biosynthesis pathway, component FlhB; type III secretion system protein SpaS 1069068 13691764 O3M_05230 Escherichia coli O104:H4 str. 2009EL-2050 type III secretion system protein SpaS YP_006768716.1 1068706 D 1134782 CDS YP_006768717.1 410481171 13691765 complement(1069130..1069423) 1 NC_018650.1 hypothetical protein 1069423 13691765 O3M_05235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768717.1 1069130 R 1134782 CDS YP_006768718.1 410481172 13691766 complement(1069425..1069925) 1 NC_018650.1 COG2771 DNA-binding HTH domain-containing proteins; response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain 1069925 13691766 O3M_05240 Escherichia coli O104:H4 str. 2009EL-2050 response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_006768718.1 1069425 R 1134782 CDS YP_006768719.1 410481173 13691767 1070183..1071364 1 NC_018650.1 type III secretion EprH protein 1071364 13691767 O3M_05245 Escherichia coli O104:H4 str. 2009EL-2050 type III secretion EprH protein YP_006768719.1 1070183 D 1134782 CDS YP_006768720.1 410481174 13691768 1071378..1071533 1 NC_018650.1 type III secretion protein EprI 1071533 13691768 O3M_05250 Escherichia coli O104:H4 str. 2009EL-2050 type III secretion protein EprI YP_006768720.1 1071378 D 1134782 CDS YP_006768721.1 410481175 13691769 1071710..1071925 1 NC_018650.1 type III secretion protein EprJ 1071925 13691769 O3M_05255 Escherichia coli O104:H4 str. 2009EL-2050 type III secretion protein EprJ YP_006768721.1 1071710 D 1134782 CDS YP_006768722.1 410481176 13691770 1071966..1072700 1 NC_018650.1 COG4669 Type III secretory pathway, lipoprotein EscJ; type III secretion system lipoprotein EprK 1072700 13691770 O3M_05260 Escherichia coli O104:H4 str. 2009EL-2050 type III secretion system lipoprotein EprK YP_006768722.1 1071966 D 1134782 CDS YP_006768723.1 410481177 13691771 1072716..1073297 1 NC_018650.1 hypothetical protein 1073297 13691771 O3M_05265 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768723.1 1072716 D 1134782 CDS YP_006768724.1 410481178 13691772 1073514..1073945 1 NC_018650.1 hypothetical protein 1073945 13691772 O3M_05270 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768724.1 1073514 D 1134782 CDS YP_006768725.1 410481179 13691773 1074166..1074321 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 1074321 13691773 O3M_05275 Escherichia coli O104:H4 str. 2009EL-2050 two component LuxR family transcriptional regulator YP_006768725.1 1074166 D 1134782 CDS YP_006768726.1 410481180 13691774 1074355..1074798 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; hypothetical protein 1074798 13691774 O3M_05280 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768726.1 1074355 D 1134782 CDS YP_006768727.1 410481181 13691775 complement(1074843..1075217) 1 NC_018650.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); peptidoglycan-binding-like protein precursor 1075217 13691775 O3M_05285 Escherichia coli O104:H4 str. 2009EL-2050 peptidoglycan-binding-like protein precursor YP_006768727.1 1074843 R 1134782 CDS YP_006768728.1 410481182 13691776 complement(1075402..1075620) 1 NC_018650.1 hypothetical protein 1075620 13691776 O3M_05290 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768728.1 1075402 R 1134782 CDS YP_006768729.1 410481183 13691777 complement(1075788..1077164) 1 NC_018650.1 COG3710 DNA-binding winged-HTH domains; transcriptional regulator 1077164 13691777 O3M_05295 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768729.1 1075788 R 1134782 CDS YP_006768730.1 410481184 13691778 complement(1077499..1077990) 1 NC_018650.1 COG0457 FOG: TPR repeat; chaperone 1077990 13691778 O3M_05300 Escherichia coli O104:H4 str. 2009EL-2050 chaperone YP_006768730.1 1077499 R 1134782 CDS YP_006768731.1 410481185 13691779 complement(1078268..1078705) 1 NC_018650.1 hypothetical protein 1078705 13691779 O3M_05305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768731.1 1078268 R 1134782 CDS YP_006768732.1 410481186 13691780 1079360..1079440 1 NC_018650.1 hypothetical protein 1079440 13691780 O3M_05310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768732.1 1079360 D 1134782 CDS YP_006768733.1 410481187 13691781 complement(1079473..1079955) 1 NC_018650.1 hypothetical protein 1079955 13691781 O3M_05315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768733.1 1079473 R 1134782 CDS YP_006768734.1 410481188 13691782 complement(1079948..1080757) 1 NC_018650.1 COG3710 DNA-binding winged-HTH domains; transcriptional regulator 1080757 13691782 O3M_05320 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768734.1 1079948 R 1134782 CDS YP_006768735.1 410481189 13691783 complement(1081091..1081723) 1 NC_018650.1 bipartite regulator domain; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; yqeH protein 1081723 13691783 O3M_05325 Escherichia coli O104:H4 str. 2009EL-2050 yqeH protein YP_006768735.1 1081091 R 1134782 CDS YP_006768736.1 410481190 13691784 complement(1082183..1083412) 1 NC_018650.1 COG0814 Amino acid permeases; transporter protein 1083412 13691784 O3M_05330 Escherichia coli O104:H4 str. 2009EL-2050 transporter protein YP_006768736.1 1082183 R 1134782 CDS YP_006768737.1 410481191 13691785 1083667..1084848 1 NC_018650.1 COG0183 Acetyl-CoA acetyltransferase; acyltransferase 1084848 13691785 O3M_05335 Escherichia coli O104:H4 str. 2009EL-2050 acyltransferase YP_006768737.1 1083667 D 1134782 CDS YP_006768738.1 410481192 13691786 1085135..1085971 1 NC_018650.1 COG3717 5-keto 4-deoxyuronate isomerase; 5-keto-4-deoxyuronate isomerase 1085971 13691786 O3M_05340 Escherichia coli O104:H4 str. 2009EL-2050 5-keto-4-deoxyuronate isomerase YP_006768738.1 1085135 D 1134782 CDS YP_006768739.1 410481193 13691787 1086001..1086762 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2-deoxy-D-gluconate 3-dehydrogenase 1086762 13691787 O3M_05345 Escherichia coli O104:H4 str. 2009EL-2050 2-deoxy-D-gluconate 3-dehydrogenase YP_006768739.1 1086001 D 1134782 CDS YP_006768740.1 410481194 13691788 1087077..1088495 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; sugar transporter 1088495 13691788 O3M_05350 Escherichia coli O104:H4 str. 2009EL-2050 sugar transporter YP_006768740.1 1087077 D 1134782 CDS YP_006768741.1 410481195 13691789 1088624..1089316 1 NC_018650.1 COG1794 Aspartate racemase; racemase 1089316 13691789 O3M_05355 Escherichia coli O104:H4 str. 2009EL-2050 racemase YP_006768741.1 1088624 D 1134782 CDS YP_006768742.1 410481196 13691790 complement(1089303..1090238) 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator LysR 1090238 13691790 O3M_05360 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator LysR YP_006768742.1 1089303 R 1134782 CDS YP_006768743.1 410481197 13691791 1090360..1091622 1 NC_018650.1 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 1091622 13691791 O3M_05365 Escherichia coli O104:H4 str. 2009EL-2050 diaminopimelate decarboxylase YP_006768743.1 1090360 D 1134782 CDS YP_006768744.1 410481198 13691792 complement(1091629..1092660) 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional regulator GalR 1092660 13691792 O3M_05370 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator GalR YP_006768744.1 1091629 R 1134782 CDS YP_006768745.1 410481199 13691793 1093246..1095405 1 NC_018650.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 1095405 13691793 O3M_05375 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_006768745.1 1093246 D 1134782 CDS YP_006768746.1 410481200 13691794 1095398..1096591 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; lysophospholipid transporter LplT 1096591 13691794 O3M_05380 Escherichia coli O104:H4 str. 2009EL-2050 lysophospholipid transporter LplT YP_006768746.1 1095398 D 1134782 CDS YP_006768747.1 410481201 13691795 complement(1096623..1097663) 1 NC_018650.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo-keto reductase 1097663 tas 13691795 tas Escherichia coli O104:H4 str. 2009EL-2050 aldo-keto reductase YP_006768747.1 1096623 R 1134782 CDS YP_006768748.1 410481202 13691796 complement(1097771..1097989) 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; hypothetical protein 1097989 13691796 O3M_05390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768748.1 1097771 R 1134782 CDS YP_006768749.1 410481203 13691797 complement(1098127..1098840) 1 NC_018650.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 1098840 13691797 O3M_05395 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768749.1 1098127 R 1134782 CDS YP_006768750.1 410481204 13691798 complement(1098909..1099598) 1 NC_018650.1 COG3066 DNA mismatch repair protein; DNA mismatch repair protein 1099598 13691798 O3M_05400 Escherichia coli O104:H4 str. 2009EL-2050 DNA mismatch repair protein YP_006768750.1 1098909 R 1134782 CDS YP_006768751.1 410481205 13691799 1100283..1100813 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; RNA pyrophosphohydrolase 1100813 13691799 O3M_05405 Escherichia coli O104:H4 str. 2009EL-2050 RNA pyrophosphohydrolase YP_006768751.1 1100283 D 1134782 CDS YP_006768752.1 410481206 13691800 1100826..1103072 1 NC_018650.1 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; COG3605 Signal transduction protein containing GAF and PtsI domains; ptsP product 1103072 13691800 O3M_05410 Escherichia coli O104:H4 str. 2009EL-2050 ptsP product YP_006768752.1 1100826 D 1134782 CDS YP_006768753.1 410481207 13691801 1103223..1104098 1 NC_018650.1 COG0682 Prolipoprotein diacylglyceryltransferase; prolipoprotein diacylglyceryl transferase 1104098 13691801 O3M_05415 Escherichia coli O104:H4 str. 2009EL-2050 prolipoprotein diacylglyceryl transferase YP_006768753.1 1103223 D 1134782 CDS YP_006768754.1 410481208 13691802 1104105..1104899 1 NC_018650.1 COG0207 Thymidylate synthase; thymidylate synthase 1104899 thyA 13691802 thyA Escherichia coli O104:H4 str. 2009EL-2050 thymidylate synthase YP_006768754.1 1104105 D 1134782 CDS YP_006768755.1 410481209 13691803 1105084..1105554 1 NC_018650.1 COG2165 Type II secretory pathway, pseudopilin PulG; hypothetical protein 1105554 13691803 O3M_05425 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768755.1 1105084 D 1134782 CDS YP_006768756.1 410481210 13691804 1105545..1106108 1 NC_018650.1 COG4795 Type II secretory pathway, component PulJ; hypothetical protein 1106108 13691804 O3M_05430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768756.1 1105545 D 1134782 CDS YP_006768757.1 410481211 13691805 1106105..1106512 1 NC_018650.1 hypothetical protein 1106512 13691805 O3M_05435 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768757.1 1106105 D 1134782 CDS YP_006768758.1 410481212 13691806 1106497..1106820 1 NC_018650.1 hypothetical protein 1106820 13691806 O3M_05440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768758.1 1106497 D 1134782 CDS YP_006768759.1 410481213 13691807 1106833..1110201 1 NC_018650.1 COG1330 Exonuclease V gamma subunit; exonuclease V subunit gamma 1110201 recC 13691807 recC Escherichia coli O104:H4 str. 2009EL-2050 exonuclease V subunit gamma YP_006768759.1 1106833 D 1134782 CDS YP_006768760.1 410481214 13691808 1110377..1113265 1 NC_018650.1 COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; protease3 1113265 13691808 O3M_05450 Escherichia coli O104:H4 str. 2009EL-2050 protease3 YP_006768760.1 1110377 D 1134782 CDS YP_006768761.1 410481215 13691809 1113258..1116800 1 NC_018650.1 COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); exonuclease V subunit beta 1116800 recB 13691809 recB Escherichia coli O104:H4 str. 2009EL-2050 exonuclease V subunit beta YP_006768761.1 1113258 D 1134782 CDS YP_006768762.1 410481216 13691810 1116800..1118626 1 NC_018650.1 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; exonuclease V subunit alpha 1118626 recD 13691810 recD Escherichia coli O104:H4 str. 2009EL-2050 exonuclease V subunit alpha YP_006768762.1 1116800 D 1134782 CDS YP_006768763.1 410481217 13691811 complement(1118688..1120019) 1 NC_018650.1 COG0548 Acetylglutamate kinase; N-acetylglutamate synthase 1120019 13691811 O3M_05465 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylglutamate synthase YP_006768763.1 1118688 R 1134782 CDS YP_006768764.1 410481218 13691812 1120251..1121504 1 NC_018650.1 COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 1121504 13691812 O3M_05470 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmuramoyl-L-alanine amidase YP_006768764.1 1120251 D 1134782 CDS YP_006768765.1 410481219 13691814 1121863..1122960 1 NC_018650.1 COG2821 Membrane-bound lytic murein transglycosylase; murein transglycosylase A 1122960 mltA 13691814 mltA Escherichia coli O104:H4 str. 2009EL-2050 murein transglycosylase A YP_006768765.1 1121863 D 1134782 CDS YP_006768766.1 410481220 13691815 1123037..1123843 1 NC_018650.1 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; sulfur acceptor protein CsdL 1123843 13691815 O3M_05480 Escherichia coli O104:H4 str. 2009EL-2050 sulfur acceptor protein CsdL YP_006768766.1 1123037 D 1134782 CDS YP_006768767.1 410481221 13691816 complement(1123894..1124337) 1 NC_018650.1 COG2166 SufE protein probably involved in Fe-S center assembly; CsdA-binding activator 1124337 13691816 O3M_05485 Escherichia coli O104:H4 str. 2009EL-2050 CsdA-binding activator YP_006768767.1 1123894 R 1134782 CDS YP_006768768.1 410481222 13691817 complement(1124337..1125542) 1 NC_018650.1 COG0520 Selenocysteine lyase; cysteine sulfinate desulfinase 1125542 13691817 O3M_05490 Escherichia coli O104:H4 str. 2009EL-2050 cysteine sulfinate desulfinase YP_006768768.1 1124337 R 1134782 CDS YP_006768769.1 410481223 13691818 1125734..1125961 1 NC_018650.1 hypothetical protein 1125961 13691818 O3M_05495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768769.1 1125734 D 1134782 CDS YP_006768770.1 410481224 13691819 1126312..1127229 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional activator GcvA 1127229 13691819 O3M_05500 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator GcvA YP_006768770.1 1126312 D 1134782 CDS YP_006768771.1 410481225 13691820 1127248..1127643 1 NC_018650.1 COG2363 Uncharacterized small membrane protein; hypothetical protein 1127643 13691820 O3M_05505 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768771.1 1127248 D 1134782 CDS YP_006768772.1 410481226 13691821 1127636..1128736 1 NC_018650.1 COG2933 Predicted SAM-dependent methyltransferase; 23S rRNA C2498 ribose 2'-O-ribose methyltransferase 1128736 13691821 O3M_05510 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA C2498 ribose 2'-O-ribose methyltransferase YP_006768772.1 1127636 D 1134782 CDS YP_006768773.1 410481227 13691822 complement(1128780..1129511) 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional activator FucR 1129511 13691822 O3M_05515 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator FucR YP_006768773.1 1128780 R 1134782 CDS YP_006768774.1 410481228 13691823 complement(1129569..1129991) 1 NC_018650.1 COG4154 Fucose dissimilation pathway protein FucU; L-fucose mutarotase 1129991 fucU 13691823 fucU Escherichia coli O104:H4 str. 2009EL-2050 L-fucose mutarotase YP_006768774.1 1129569 R 1134782 CDS YP_006768775.1 410481229 13691824 complement(1129993..1131411) 1 NC_018650.1 COG1070 Sugar (pentulose and hexulose) kinases; L-fuculokinase 1131411 13691824 O3M_05525 Escherichia coli O104:H4 str. 2009EL-2050 L-fuculokinase YP_006768775.1 1129993 R 1134782 CDS YP_006768776.1 410481230 13691825 complement(1131520..1133295) 1 NC_018650.1 COG2407 L-fucose isomerase and related proteins; L-fucose isomerase 1133295 fucI 13691825 fucI Escherichia coli O104:H4 str. 2009EL-2050 L-fucose isomerase YP_006768776.1 1131520 R 1134782 CDS YP_006768777.1 410481231 13691826 complement(1133328..1134644) 1 NC_018650.1 COG0738 Fucose permease; L-fucose transporter 1134644 13691826 O3M_05535 Escherichia coli O104:H4 str. 2009EL-2050 L-fucose transporter YP_006768777.1 1133328 R 1134782 CDS YP_006768778.1 410481232 13691827 1135191..1135838 1 NC_018650.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-fuculose phosphate aldolase 1135838 13691827 O3M_05540 Escherichia coli O104:H4 str. 2009EL-2050 L-fuculose phosphate aldolase YP_006768778.1 1135191 D 1134782 CDS YP_006768779.1 410481233 13691828 1135866..1137014 1 NC_018650.1 COG1454 Alcohol dehydrogenase, class IV; L-1,2-propanediol oxidoreductase 1137014 13691828 O3M_05545 Escherichia coli O104:H4 str. 2009EL-2050 L-1,2-propanediol oxidoreductase YP_006768779.1 1135866 D 1134782 CDS YP_006768780.1 410481234 13691829 complement(1137069..1137914) 1 NC_018650.1 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); flap endonuclease-like protein 1137914 13691829 O3M_05550 Escherichia coli O104:H4 str. 2009EL-2050 flap endonuclease-like protein YP_006768780.1 1137069 R 1134782 CDS YP_006768781.1 410481235 13691830 complement(1137936..1139303) 1 NC_018650.1 COG1760 L-serine deaminase; L-serine deaminase II 1139303 13691830 O3M_05555 Escherichia coli O104:H4 str. 2009EL-2050 L-serine deaminase II YP_006768781.1 1137936 R 1134782 CDS YP_006768782.1 410481236 13691831 complement(1139361..1140650) 1 NC_018650.1 COG0814 Amino acid permeases; serine transporter 1140650 13691831 O3M_05560 Escherichia coli O104:H4 str. 2009EL-2050 serine transporter YP_006768782.1 1139361 R 1134782 CDS YP_006768783.1 410481237 13691832 complement(1141207..1142571) 1 NC_018650.1 COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein 1142571 13691832 O3M_05565 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768783.1 1141207 R 1134782 CDS YP_006768784.1 410481238 13691833 complement(1142683..1143531) 1 NC_018650.1 COG2904 Uncharacterized protein conserved in bacteria; 7-cyano-7-deazaguanine reductase 1143531 queF 13691833 queF Escherichia coli O104:H4 str. 2009EL-2050 7-cyano-7-deazaguanine reductase YP_006768784.1 1142683 R 1134782 CDS YP_006768785.1 410481239 13691834 1143599..1144144 1 NC_018650.1 SecY interacting protein Syd 1144144 13691834 O3M_05575 Escherichia coli O104:H4 str. 2009EL-2050 SecY interacting protein Syd YP_006768785.1 1143599 D 1134782 CDS YP_006768786.1 410481240 13691835 1144379..1144519 1 NC_018650.1 hypothetical protein 1144519 13691835 O3M_05580 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768786.1 1144379 D 1134782 CDS YP_006768787.1 410481241 13691836 1144766..1145095 1 NC_018650.1 COG3098 Uncharacterized protein conserved in bacteria; hypothetical protein 1145095 13691836 O3M_05585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768787.1 1144766 D 1134782 CDS YP_006768788.1 410481242 13691837 1145895..1146344 1 NC_018650.1 COG0716 Flavodoxins; flavodoxin 1146344 13691837 O3M_05600 Escherichia coli O104:H4 str. 2009EL-2050 flavodoxin YP_006768788.1 1145895 D 1134782 CDS YP_006768789.1 410481243 13691919 1146779..1148131 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; D-glucarate transporter GudP 1148131 13691919 O3M_05605 Escherichia coli O104:H4 str. 2009EL-2050 D-glucarate transporter GudP YP_006768789.1 1146779 D 1134782 CDS YP_006768790.1 410481244 13691920 1149494..1150834 1 NC_018650.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; (D)-glucarate dehydratase 1 1150834 13691920 O3M_05620 Escherichia coli O104:H4 str. 2009EL-2050 (D)-glucarate dehydratase 1 YP_006768790.1 1149494 D 1134782 CDS YP_006768791.1 410481245 13691921 complement(1151066..1153822) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; hybrid sensory histidine kinase BarA 1153822 13691921 O3M_05625 Escherichia coli O104:H4 str. 2009EL-2050 hybrid sensory histidine kinase BarA YP_006768791.1 1151066 R 1134782 CDS YP_006768792.1 410481246 13691922 1153879..1155180 1 NC_018650.1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; 23S rRNA m(5)U1939 methyltransferase 1155180 rumA 13691922 rumA Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA m(5)U1939 methyltransferase YP_006768792.1 1153879 D 1134782 CDS YP_006768793.1 410481247 13691923 1155228..1157462 1 NC_018650.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; (p)ppGpp synthetase I 1157462 relA 13691923 relA Escherichia coli O104:H4 str. 2009EL-2050 (p)ppGpp synthetase I YP_006768793.1 1155228 D 1134782 CDS YP_006768794.1 410481248 13691924 1157540..1157788 1 NC_018650.1 COG2336 Growth regulator; antitoxin MazE 1157788 13691924 O3M_05640 Escherichia coli O104:H4 str. 2009EL-2050 antitoxin MazE YP_006768794.1 1157540 D 1134782 CDS YP_006768795.1 410481249 13691925 1157788..1158123 1 NC_018650.1 COG2337 Growth inhibitor; toxin MazF 1158123 13691925 O3M_05645 Escherichia coli O104:H4 str. 2009EL-2050 toxin MazF YP_006768795.1 1157788 D 1134782 CDS YP_006768796.1 410481250 13691926 1158194..1158985 1 NC_018650.1 COG1694 Predicted pyrophosphatase; nucleoside triphosphate pyrophosphohydrolase 1158985 mazG 13691926 mazG Escherichia coli O104:H4 str. 2009EL-2050 nucleoside triphosphate pyrophosphohydrolase YP_006768796.1 1158194 D 1134782 CDS YP_006768797.1 410481251 13691927 1159213..1160850 1 NC_018650.1 COG0504 CTP synthase (UTP-ammonia lyase); CTP synthetase 1160850 pyrG 13691927 pyrG Escherichia coli O104:H4 str. 2009EL-2050 CTP synthetase YP_006768797.1 1159213 D 1134782 CDS YP_006768798.1 410481252 13691928 1160938..1162236 1 NC_018650.1 COG0148 Enolase; enolase 1162236 eno 13691928 eno Escherichia coli O104:H4 str. 2009EL-2050 enolase YP_006768798.1 1160938 D 1134782 CDS YP_006768799.1 410481253 13691929 complement(1162220..1162372) 1 NC_018650.1 hypothetical protein 1162372 13691929 O3M_05665 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768799.1 1162220 R 1134782 CDS YP_006768800.1 410481254 13691930 complement(1162296..1163000) 1 NC_018650.1 COG1512 Beta-propeller domains of methanol dehydrogenase type; hypothetical protein 1163000 13691930 O3M_05670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768800.1 1162296 R 1134782 CDS YP_006768801.1 410481255 13691931 complement(1163182..1163322) 1 NC_018650.1 hypothetical protein 1163322 13691931 O3M_05675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768801.1 1163182 R 1134782 CDS YP_006768802.1 410481256 13691932 1163461..1164132 1 NC_018650.1 COG0602 Organic radical activating enzymes; hypothetical protein 1164132 13691932 O3M_05680 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768802.1 1163461 D 1134782 CDS YP_006768803.1 410481257 13691933 complement(1164774..1164995) 1 NC_018650.1 hypothetical protein 1164995 13691933 O3M_05685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768803.1 1164774 R 1134782 CDS YP_006768804.1 410481258 13691934 complement(1165932..1167410) 1 NC_018650.1 COG1070 Sugar (pentulose and hexulose) kinases; kinase 1167410 13691934 O3M_05690 Escherichia coli O104:H4 str. 2009EL-2050 kinase YP_006768804.1 1165932 R 1134782 CDS YP_006768805.1 410481259 13691935 complement(1167437..1168714) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 1168714 13691935 O3M_05695 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768805.1 1167437 R 1134782 CDS YP_006768806.1 410481260 13691936 1169033..1169818 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1169818 13691936 O3M_05700 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006768806.1 1169033 D 1134782 CDS YP_006768807.1 410481261 13691937 1169888..1171342 1 NC_018650.1 COG0277 FAD/FMN-containing dehydrogenases; FAD containing dehydrogenase 1171342 13691937 O3M_05705 Escherichia coli O104:H4 str. 2009EL-2050 FAD containing dehydrogenase YP_006768807.1 1169888 D 1134782 CDS YP_006768808.1 410481262 13691938 1171436..1172773 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 1172773 13691938 O3M_05710 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768808.1 1171436 D 1134782 CDS YP_006768809.1 410481263 13691939 1172751..1173530 1 NC_018650.1 COG2086 Electron transfer flavoprotein, beta subunit; electron transfer flavoprotein 1173530 13691939 O3M_05715 Escherichia coli O104:H4 str. 2009EL-2050 electron transfer flavoprotein YP_006768809.1 1172751 D 1134782 CDS YP_006768810.1 410481264 13691940 1173527..1174387 1 NC_018650.1 COG2025 Electron transfer flavoprotein, alpha subunit; flavoprotein 1174387 13691940 O3M_05720 Escherichia coli O104:H4 str. 2009EL-2050 flavoprotein YP_006768810.1 1173527 D 1134782 CDS YP_006768811.1 410481265 13691941 complement(1174535..1175110) 1 NC_018650.1 COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding); anti-terminator regulatory protein 1175110 13691941 O3M_05725 Escherichia coli O104:H4 str. 2009EL-2050 anti-terminator regulatory protein YP_006768811.1 1174535 R 1134782 CDS YP_006768812.1 410481266 13691942 complement(1175127..1175387) 1 NC_018650.1 COG2440 Ferredoxin-like protein; 4Fe-4S binding protein 1175387 13691942 O3M_05730 Escherichia coli O104:H4 str. 2009EL-2050 4Fe-4S binding protein YP_006768812.1 1175127 R 1134782 CDS YP_006768813.1 410481267 13691943 complement(1175378..1176649) 1 NC_018650.1 COG0644 Dehydrogenases (flavoproteins); oxidoreductase with FAD/NAD(P)-binding domain 1176649 13691943 O3M_05735 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase with FAD/NAD(P)-binding domain YP_006768813.1 1175378 R 1134782 CDS YP_006768814.1 410481268 13691944 complement(1176727..1177089) 1 NC_018650.1 COG0720 6-pyruvoyl-tetrahydropterin synthase; 6-pyruvoyl tetrahydrobiopterin synthase 1177089 13691944 O3M_05740 Escherichia coli O104:H4 str. 2009EL-2050 6-pyruvoyl tetrahydrobiopterin synthase YP_006768814.1 1176727 R 1134782 CDS YP_006768815.1 410481269 13691945 1177408..1179207 1 NC_018650.1 COG0369 Sulfite reductase, alpha subunit (flavoprotein); sulfite reductase subunit alpha 1179207 cysJ 13691945 cysJ Escherichia coli O104:H4 str. 2009EL-2050 sulfite reductase subunit alpha YP_006768815.1 1177408 D 1134782 CDS YP_006768816.1 410481270 13691946 1179207..1180919 1 NC_018650.1 COG0155 Sulfite reductase, beta subunit (hemoprotein); sulfite reductase subunit beta 1180919 13691946 O3M_05750 Escherichia coli O104:H4 str. 2009EL-2050 sulfite reductase subunit beta YP_006768816.1 1179207 D 1134782 CDS YP_006768817.1 410481271 13691947 1180993..1181727 1 NC_018650.1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; phosphoadenosine phosphosulfate reductase 1181727 13691947 O3M_05755 Escherichia coli O104:H4 str. 2009EL-2050 phosphoadenosine phosphosulfate reductase YP_006768817.1 1180993 D 1134782 CDS YP_006768818.1 410481272 13691948 1181992..1182144 1 NC_018650.1 small toxic membrane polypeptide 1182144 13691948 O3M_05760 Escherichia coli O104:H4 str. 2009EL-2050 small toxic membrane polypeptide YP_006768818.1 1181992 D 1134782 CDS YP_006768819.1 410481273 13691949 1182221..1183333 1 NC_018650.1 COG3385 FOG: Transposase and inactivated derivatives; transposase insL for insertion sequence IS186 1183333 13691949 O3M_05765 Escherichia coli O104:H4 str. 2009EL-2050 transposase insL for insertion sequence IS186 YP_006768819.1 1182221 D 1134782 CDS YP_006768820.1 410481274 13691950 1183729..1186386 1 NC_018650.1 COG1203 Predicted helicases; hypothetical protein 1186386 13691950 O3M_05770 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768820.1 1183729 D 1134782 CDS YP_006768821.1 410481275 13691951 1186484..1188046 1 NC_018650.1 hypothetical protein 1188046 13691951 O3M_05775 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768821.1 1186484 D 1134782 CDS YP_006768822.1 410481276 13691952 1188043..1188579 1 NC_018650.1 hypothetical protein 1188579 13691952 O3M_05780 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768822.1 1188043 D 1134782 CDS YP_006768823.1 410481277 13691953 1188591..1189646 1 NC_018650.1 hypothetical protein 1189646 13691953 O3M_05785 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768823.1 1188591 D 1134782 CDS YP_006768824.1 410481278 13691954 1189657..1190403 1 NC_018650.1 hypothetical protein 1190403 13691954 O3M_05790 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768824.1 1189657 D 1134782 CDS YP_006768825.1 410481279 13691955 1190385..1191035 1 NC_018650.1 hypothetical protein 1191035 13691955 O3M_05795 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768825.1 1190385 D 1134782 CDS YP_006768826.1 410481280 13691956 1191032..1191952 1 NC_018650.1 COG1518 Uncharacterized protein predicted to be involved in DNA repair; CRISPR-associated protein Cas1 1191952 13691956 O3M_05800 Escherichia coli O104:H4 str. 2009EL-2050 CRISPR-associated protein Cas1 YP_006768826.1 1191032 D 1134782 CDS YP_006768827.1 410481281 13691957 1191952..1192245 1 NC_018650.1 ssRNA endonuclease 1192245 13691957 O3M_05805 Escherichia coli O104:H4 str. 2009EL-2050 ssRNA endonuclease YP_006768827.1 1191952 D 1134782 CDS YP_006768828.1 410481282 13691958 complement(1192513..1193550) 1 NC_018650.1 COG2234 Predicted aminopeptidases; alkaline phosphatase isozyme conversion aminopeptidase 1193550 13691958 O3M_05810 Escherichia coli O104:H4 str. 2009EL-2050 alkaline phosphatase isozyme conversion aminopeptidase YP_006768828.1 1192513 R 1134782 CDS YP_006768829.1 410481283 13691959 1193802..1194710 1 NC_018650.1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; sulfate adenylyltransferase subunit 2 1194710 13691959 O3M_05815 Escherichia coli O104:H4 str. 2009EL-2050 sulfate adenylyltransferase subunit 2 YP_006768829.1 1193802 D 1134782 CDS YP_006768830.1 410481284 13691960 1194712..1196139 1 NC_018650.1 COG2895 GTPases - Sulfate adenylate transferase subunit 1; sulfate adenylyltransferase subunit 1 1196139 cysN 13691960 cysN Escherichia coli O104:H4 str. 2009EL-2050 sulfate adenylyltransferase subunit 1 YP_006768830.1 1194712 D 1134782 CDS YP_006768831.1 410481285 13691961 1196139..1196744 1 NC_018650.1 COG0529 Adenylylsulfate kinase and related kinases; adenylylsulfate kinase 1196744 13691961 O3M_05825 Escherichia coli O104:H4 str. 2009EL-2050 adenylylsulfate kinase YP_006768831.1 1196139 D 1134782 CDS YP_006768832.1 410481286 13691962 1196794..1197117 1 NC_018650.1 COG0665 Glycine/D-amino acid oxidases (deaminating); hypothetical protein 1197117 13691962 O3M_05830 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768832.1 1196794 D 1134782 CDS YP_006768833.1 410481287 13691963 1197311..1197622 1 NC_018650.1 COG2919 Septum formation initiator; cell division protein FtsB 1197622 ftsB 13691963 ftsB Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsB YP_006768833.1 1197311 D 1134782 CDS YP_006768834.1 410481288 13691964 1197641..1198351 1 NC_018650.1 COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1198351 ispD 13691964 ispD Escherichia coli O104:H4 str. 2009EL-2050 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_006768834.1 1197641 D 1134782 CDS YP_006768835.1 410481289 13691965 1198351..1198830 1 NC_018650.1 COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 1198830 ispF 13691965 ispF Escherichia coli O104:H4 str. 2009EL-2050 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase YP_006768835.1 1198351 D 1134782 CDS YP_006768836.1 410481290 13691966 1198827..1199876 1 NC_018650.1 COG0585 Uncharacterized conserved protein; tRNA pseudouridine synthase D 1199876 truD 13691966 truD Escherichia coli O104:H4 str. 2009EL-2050 tRNA pseudouridine synthase D YP_006768836.1 1198827 D 1134782 CDS YP_006768837.1 410481291 13691967 1199857..1200618 1 NC_018650.1 COG0496 Predicted acid phosphatase; 5'(3')-nucleotidase/polyphosphatase 1200618 surE 13691967 surE Escherichia coli O104:H4 str. 2009EL-2050 5'(3')-nucleotidase/polyphosphatase YP_006768837.1 1199857 D 1134782 CDS YP_006768838.1 410481292 13691968 1200612..1201238 1 NC_018650.1 COG2518 Protein-L-isoaspartate carboxylmethyltransferase; protein-L-isoaspartate O-methyltransferase 1201238 pcm 13691968 pcm Escherichia coli O104:H4 str. 2009EL-2050 protein-L-isoaspartate O-methyltransferase YP_006768838.1 1200612 D 1134782 CDS YP_006768839.1 410481293 13691969 1201378..1202517 1 NC_018650.1 COG0739 Membrane proteins related to metalloendopeptidases; lipoprotein NlpD 1202517 nlpD 13691969 nlpD Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein NlpD YP_006768839.1 1201378 D 1134782 CDS YP_006768840.1 410481294 13691970 1202580..1203572 1 NC_018650.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor RpoS 1203572 13691970 O3M_05870 Escherichia coli O104:H4 str. 2009EL-2050 RNA polymerase sigma factor RpoS YP_006768840.1 1202580 D 1134782 CDS YP_006768841.1 410481295 13691971 complement(1203693..1204100) 1 NC_018650.1 COG1846 Transcriptional regulators; transcriptional regulator hosA 1204100 13691971 O3M_05875 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator hosA YP_006768841.1 1203693 R 1134782 CDS YP_006768842.1 410481296 13691972 1204247..1204840 1 NC_018650.1 COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; phenylacrylic acid decarboxylase 1204840 13691972 O3M_05880 Escherichia coli O104:H4 str. 2009EL-2050 phenylacrylic acid decarboxylase YP_006768842.1 1204247 D 1134782 CDS YP_006768843.1 410481297 13691973 1204840..1206267 1 NC_018650.1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; 4-hydroxybenzoate decarboxylase 1206267 13691973 O3M_05885 Escherichia coli O104:H4 str. 2009EL-2050 4-hydroxybenzoate decarboxylase YP_006768843.1 1204840 D 1134782 CDS YP_006768844.1 410481298 13691974 1206278..1206514 1 NC_018650.1 non-oxidative reversible hydroxyarylic acid decarboxylase 1206514 13691974 O3M_05890 Escherichia coli O104:H4 str. 2009EL-2050 non-oxidative reversible hydroxyarylic acid decarboxylase YP_006768844.1 1206278 D 1134782 CDS YP_006768845.1 410481299 13691975 complement(1206554..1207918) 1 NC_018650.1 COG2610 H+/gluconate symporter and related permeases; transporter 1207918 13691975 O3M_05895 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006768845.1 1206554 R 1134782 CDS YP_006768846.1 410481300 13691976 complement(1208007..1208783) 1 NC_018650.1 COG3622 Hydroxypyruvate isomerase; hypothetical protein 1208783 13691976 O3M_05900 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768846.1 1208007 R 1134782 CDS YP_006768847.1 410481301 13691977 complement(1208788..1209426) 1 NC_018650.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; aldolase 1209426 13691977 O3M_05905 Escherichia coli O104:H4 str. 2009EL-2050 aldolase YP_006768847.1 1208788 R 1134782 CDS YP_006768848.1 410481302 13691978 complement(1209423..1210685) 1 NC_018650.1 COG3395 Uncharacterized protein conserved in bacteria; hypothetical protein 1210685 13691978 O3M_05910 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768848.1 1209423 R 1134782 CDS YP_006768849.1 410481303 13691979 complement(1210682..1211590) 1 NC_018650.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; dehydrogenase 1211590 13691979 O3M_05915 Escherichia coli O104:H4 str. 2009EL-2050 dehydrogenase YP_006768849.1 1210682 R 1134782 CDS YP_006768850.1 410481304 13691980 1211786..1212553 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 1212553 13691980 O3M_05920 Escherichia coli O104:H4 str. 2009EL-2050 DeoR family transcriptional regulator YP_006768850.1 1211786 D 1134782 CDS YP_006768851.1 410481305 13691981 complement(1212604..1213260) 1 NC_018650.1 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; serine/threonine-specific protein phosphatase 2 1213260 13691981 O3M_05925 Escherichia coli O104:H4 str. 2009EL-2050 serine/threonine-specific protein phosphatase 2 YP_006768851.1 1212604 R 1134782 CDS YP_006768852.1 410481306 13691982 complement(1213366..1215927) 1 NC_018650.1 COG0249 Mismatch repair ATPase (MutS family); DNA mismatch repair protein MutS 1215927 13691982 O3M_05930 Escherichia coli O104:H4 str. 2009EL-2050 DNA mismatch repair protein MutS YP_006768852.1 1213366 R 1134782 CDS YP_006768853.1 410481307 13691983 1216003..1216182 1 NC_018650.1 hypothetical protein 1216182 13691983 O3M_05935 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768853.1 1216003 D 1134782 CDS YP_006768854.1 410481308 13691984 1216214..1216567 1 NC_018650.1 hypothetical protein 1216567 13691984 O3M_05940 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768854.1 1216214 D 1134782 CDS YP_006768855.1 410481309 13691985 complement(1216604..1218682) 1 NC_018650.1 COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; formate hydrogenlyase transcriptional activator FhlA 1218682 13691985 O3M_05945 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase transcriptional activator FhlA YP_006768855.1 1216604 R 1134782 CDS YP_006768856.1 410481310 13691986 complement(1218756..1219766) 1 NC_018650.1 COG0309 Hydrogenase maturation factor; hydrogenase expression/formation protein HypE 1219766 13691986 O3M_05950 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase expression/formation protein HypE YP_006768856.1 1218756 R 1134782 CDS YP_006768857.1 410481311 13691987 complement(1219763..1220884) 1 NC_018650.1 COG0409 Hydrogenase maturation factor; hydrogenase expression/formation protein HypD 1220884 13691987 O3M_05955 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase expression/formation protein HypD YP_006768857.1 1219763 R 1134782 CDS YP_006768858.1 410481312 13691988 complement(1220884..1221156) 1 NC_018650.1 COG0298 Hydrogenase maturation factor; hydrogenase assembly chaperone 1221156 13691988 O3M_05960 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase assembly chaperone YP_006768858.1 1220884 R 1134782 CDS YP_006768859.1 410481313 13692070 complement(1221147..1222019) 1 NC_018650.1 COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; hydrogenase nickel incorporation protein HypB 1222019 13692070 O3M_05965 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase nickel incorporation protein HypB YP_006768859.1 1221147 R 1134782 CDS YP_006768860.1 410481314 13692071 complement(1222023..1222373) 1 NC_018650.1 COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); hydrogenase nickel incorporation protein 1222373 hypA 13692071 hypA Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase nickel incorporation protein YP_006768860.1 1222023 R 1134782 CDS YP_006768861.1 410481315 13692072 1222584..1223045 1 NC_018650.1 formate hydrogenlyase regulatory protein HycA 1223045 13692072 O3M_05975 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase regulatory protein HycA YP_006768861.1 1222584 D 1134782 CDS YP_006768862.1 410481316 13692073 complement(1222961..1223269) 1 NC_018650.1 hypothetical protein 1223269 13692073 O3M_05980 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768862.1 1222961 R 1134782 CDS YP_006768863.1 410481317 13692074 1223170..1223781 1 NC_018650.1 COG1142 Fe-S-cluster-containing hydrogenase components 2; formate hydrogenlyase subunit B 1223781 13692074 O3M_05985 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase subunit B YP_006768863.1 1223170 D 1134782 CDS YP_006768864.1 410481318 13692075 1223778..1225604 1 NC_018650.1 COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; formate hydrogenlyase subunit 3 1225604 13692075 O3M_05990 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase subunit 3 YP_006768864.1 1223778 D 1134782 CDS YP_006768865.1 410481319 13692076 1225607..1226530 1 NC_018650.1 COG0650 Formate hydrogenlyase subunit 4; hydrogenase 3, membrane subunit HycD 1226530 13692076 O3M_05995 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 3, membrane subunit HycD YP_006768865.1 1225607 D 1134782 CDS YP_006768866.1 410481320 13692077 1226548..1228257 1 NC_018650.1 COG3262 Ni,Fe-hydrogenase III component G; formate hydrogenlyase subunit E 1228257 13692077 O3M_06000 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase subunit E YP_006768866.1 1226548 D 1134782 CDS YP_006768867.1 410481321 13692078 1228267..1228809 1 NC_018650.1 COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); formate hydrogenlyase complex iron-sulfur subunit 1228809 13692078 O3M_06005 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase complex iron-sulfur subunit YP_006768867.1 1228267 D 1134782 CDS YP_006768868.1 410481322 13692079 1228809..1229576 1 NC_018650.1 COG3260 Ni,Fe-hydrogenase III small subunit; hydrogenase 3 and formate hydrogenase complex, HycG subunit 1229576 13692079 O3M_06010 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 3 and formate hydrogenase complex, HycG subunit YP_006768868.1 1228809 D 1134782 CDS YP_006768869.1 410481323 13692080 1229573..1229983 1 NC_018650.1 formate hydrogenlyase maturation protein HycH 1229983 13692080 O3M_06015 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase maturation protein HycH YP_006768869.1 1229573 D 1134782 CDS YP_006768870.1 410481324 13692081 1229976..1230446 1 NC_018650.1 COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 3 maturation protease 1230446 hycI 13692081 hycI Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 3 maturation protease YP_006768870.1 1229976 D 1134782 CDS YP_006768871.1 410481325 13692082 1230471..1231244 1 NC_018650.1 hypothetical protein 1231244 13692082 O3M_06025 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768871.1 1230471 D 1134782 CDS YP_006768872.1 410481326 13692083 1231315..1231734 1 NC_018650.1 COG5499 Predicted transcription regulator containing HTH domain; HTH-type transcriptional regulator ygjM 1231734 13692083 O3M_06030 Escherichia coli O104:H4 str. 2009EL-2050 HTH-type transcriptional regulator ygjM YP_006768872.1 1231315 D 1134782 CDS YP_006768873.1 410481327 13692084 1231979..1232959 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 1232959 13692084 O3M_06035 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006768873.1 1231979 D 1134782 CDS YP_006768874.1 410481328 13692085 complement(1233127..1234551) 1 NC_018650.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; cryptic 6-phospho-beta-glucosidase 1234551 13692085 O3M_06040 Escherichia coli O104:H4 str. 2009EL-2050 cryptic 6-phospho-beta-glucosidase YP_006768874.1 1233127 R 1134782 CDS YP_006768875.1 410481329 13692086 complement(1234560..1236017) 1 NC_018650.1 COG1264 Phosphotransferase system IIB components; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 1236017 13692086 O3M_06045 Escherichia coli O104:H4 str. 2009EL-2050 PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_006768875.1 1234560 R 1134782 CDS YP_006768876.1 410481330 13692087 1236274..1237287 1 NC_018650.1 COG1609 Transcriptional regulators; transcriptional regulator 1237287 13692087 O3M_06050 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006768876.1 1236274 D 1134782 CDS YP_006768877.1 410481331 13692088 1237436..1237963 1 NC_018650.1 COG1142 Fe-S-cluster-containing hydrogenase components 2; formate dehydrogenase-H ferredoxin subunit 1237963 13692088 O3M_06055 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-H ferredoxin subunit YP_006768877.1 1237436 D 1134782 CDS YP_006768878.1 410481332 13692089 1238116..1240368 1 NC_018650.1 COG0068 Hydrogenase maturation factor; hydrogenase maturation protein 1240368 13692089 O3M_06060 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase maturation protein YP_006768878.1 1238116 D 1134782 CDS YP_006768879.1 410481333 13692090 complement(1240594..1241727) 1 NC_018650.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; NADH:flavorubredoxin oxidoreductase 1241727 13692090 O3M_06065 Escherichia coli O104:H4 str. 2009EL-2050 NADH:flavorubredoxin oxidoreductase YP_006768879.1 1240594 R 1134782 CDS YP_006768880.1 410481334 13692091 complement(1241724..1243163) 1 NC_018650.1 COG0426 Uncharacterized flavoproteins; anaerobic nitric oxide reductase flavorubredoxin 1243163 13692091 O3M_06070 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic nitric oxide reductase flavorubredoxin YP_006768880.1 1241724 R 1134782 CDS YP_006768881.1 410481335 13692092 1243350..1244864 1 NC_018650.1 COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; anaerobic nitric oxide reductase transcriptional regulator 1244864 13692092 O3M_06075 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic nitric oxide reductase transcriptional regulator YP_006768881.1 1243350 D 1134782 CDS YP_006768882.1 410481336 13692093 complement(1244861..1245826) 1 NC_018650.1 COG0794 Predicted sugar phosphate isomerase involved in capsule formation; D-arabinose 5-phosphate isomerase 1245826 gutQ 13692093 gutQ Escherichia coli O104:H4 str. 2009EL-2050 D-arabinose 5-phosphate isomerase YP_006768882.1 1244861 R 1134782 CDS YP_006768883.1 410481337 13692094 complement(1245819..1246592) 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor SrlR 1246592 srlR 13692094 srlR Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor SrlR YP_006768883.1 1245819 R 1134782 CDS YP_006768884.1 410481338 13692095 complement(1246659..1247018) 1 NC_018650.1 COG4578 Glucitol operon activator; DNA-binding transcriptional activator GutM 1247018 13692095 O3M_06090 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator GutM YP_006768884.1 1246659 R 1134782 CDS YP_006768885.1 410481339 13692096 complement(1247123..1247902) 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); sorbitol-6-phosphate dehydrogenase 1247902 13692096 O3M_06095 Escherichia coli O104:H4 str. 2009EL-2050 sorbitol-6-phosphate dehydrogenase YP_006768885.1 1247123 R 1134782 CDS YP_006768886.1 410481340 13692097 complement(1247906..1248277) 1 NC_018650.1 COG3731 Phosphotransferase system sorbitol-specific component IIA; PTS system glucitol/sorbitol-specific transporter subunit IIA 1248277 13692097 O3M_06100 Escherichia coli O104:H4 str. 2009EL-2050 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_006768886.1 1247906 R 1134782 CDS YP_006768887.1 410481341 13692098 complement(1248288..1249247) 1 NC_018650.1 COG3732 Phosphotransferase system sorbitol-specific component IIBC; PTS system glucitol/sorbitol-specific transporter subunit IIB 1249247 13692098 O3M_06105 Escherichia coli O104:H4 str. 2009EL-2050 PTS system glucitol/sorbitol-specific transporter subunit IIB YP_006768887.1 1248288 R 1134782 CDS YP_006768888.1 410481342 13692099 complement(1249244..1249807) 1 NC_018650.1 COG3730 Phosphotransferase system sorbitol-specific component IIC; glucitol/sorbitol permease IIC component 1249807 13692099 O3M_06110 Escherichia coli O104:H4 str. 2009EL-2050 glucitol/sorbitol permease IIC component YP_006768888.1 1249244 R 1134782 CDS YP_006768889.1 410481343 13692100 1250063..1251148 1 NC_018650.1 COG2951 Membrane-bound lytic murein transglycosylase B; murein hydrolase B 1251148 13692100 O3M_06115 Escherichia coli O104:H4 str. 2009EL-2050 murein hydrolase B YP_006768889.1 1250063 D 1134782 CDS YP_006768890.1 410481344 13692101 1251293..1251790 1 NC_018650.1 COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein 1251790 13692101 O3M_06120 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768890.1 1251293 D 1134782 CDS YP_006768891.1 410481345 13692102 1251870..1252931 1 NC_018650.1 COG0468 RecA/RadA recombinase; recombinase A 1252931 recA 13692102 recA Escherichia coli O104:H4 str. 2009EL-2050 recombinase A YP_006768891.1 1251870 D 1134782 CDS YP_006768892.1 410481346 13692103 1253174..1253674 1 NC_018650.1 COG2137 Uncharacterized protein conserved in bacteria; recombination regulator RecX 1253674 recX 13692103 recX Escherichia coli O104:H4 str. 2009EL-2050 recombination regulator RecX YP_006768892.1 1253174 D 1134782 CDS YP_006768893.1 410481347 13692104 complement(1253715..1253864) 1 NC_018650.1 hypothetical protein 1253864 13692104 O3M_06135 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768893.1 1253715 R 1134782 CDS YP_006768894.1 410481348 13692105 1253802..1256432 1 NC_018650.1 COG0013 Alanyl-tRNA synthetase; alanyl-tRNA synthetase 1256432 alaS 13692105 alaS Escherichia coli O104:H4 str. 2009EL-2050 alanyl-tRNA synthetase YP_006768894.1 1253802 D 1134782 CDS YP_006768895.1 410481349 13692106 1256667..1256852 1 NC_018650.1 COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); carbon storage regulator 1256852 13692106 O3M_06145 Escherichia coli O104:H4 str. 2009EL-2050 carbon storage regulator YP_006768895.1 1256667 D 1134782 CDS YP_006768896.1 410481350 13692112 1258444..1259010 1 NC_018650.1 COG0637 Predicted phosphatase/phosphohexomutase; fructose-1-P/6-phosphogluconate phosphatase 1259010 13692112 O3M_06150 Escherichia coli O104:H4 str. 2009EL-2050 fructose-1-P/6-phosphogluconate phosphatase YP_006768896.1 1258444 D 1134782 CDS YP_006768897.1 410481351 13692113 1259007..1259435 1 NC_018650.1 COG1238 Predicted membrane protein; hypothetical protein 1259435 13692113 O3M_06155 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768897.1 1259007 D 1134782 CDS YP_006768898.1 410481352 13692114 1259508..1261064 1 NC_018650.1 COG2918 Gamma-glutamylcysteine synthetase; glutamate--cysteine ligase 1261064 13692114 O3M_06160 Escherichia coli O104:H4 str. 2009EL-2050 glutamate--cysteine ligase YP_006768898.1 1259508 D 1134782 CDS YP_006768899.1 410481353 13692115 1261214..1261729 1 NC_018650.1 COG1854 LuxS protein involved in autoinducer AI2 synthesis; S-ribosylhomocysteinase 1261729 13692115 O3M_06165 Escherichia coli O104:H4 str. 2009EL-2050 S-ribosylhomocysteinase YP_006768899.1 1261214 D 1134782 CDS YP_006768900.1 410481354 13692116 complement(1261793..1263331) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; membrane translocase 1263331 13692116 O3M_06170 Escherichia coli O104:H4 str. 2009EL-2050 membrane translocase YP_006768900.1 1261793 R 1134782 CDS YP_006768901.1 410481355 13692117 complement(1263348..1264520) 1 NC_018650.1 COG1566 Multidrug resistance efflux pump; multidrug efflux system protein EmrA 1264520 13692117 O3M_06175 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein EmrA YP_006768901.1 1263348 R 1134782 CDS YP_006768902.1 410481356 13692118 complement(1264647..1265177) 1 NC_018650.1 COG1846 Transcriptional regulators; transcriptional repressor MprA 1265177 13692118 O3M_06180 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional repressor MprA YP_006768902.1 1264647 R 1134782 CDS YP_006768903.1 410481357 13692119 complement(1265268..1265603) 1 NC_018650.1 L-valine exporter 1265603 13692119 O3M_06185 Escherichia coli O104:H4 str. 2009EL-2050 L-valine exporter YP_006768903.1 1265268 R 1134782 CDS YP_006768904.1 410481358 13692120 complement(1265593..1266330) 1 NC_018650.1 COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); branched chain amino acid exporter (LIV-E) family protein 1266330 13692120 O3M_06190 Escherichia coli O104:H4 str. 2009EL-2050 branched chain amino acid exporter (LIV-E) family protein YP_006768904.1 1265593 R 1134782 CDS YP_006768905.1 410481359 13692121 complement(1266454..1267638) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transport protein (ousB-like) 1267638 13692121 O3M_06195 Escherichia coli O104:H4 str. 2009EL-2050 transport protein (ousB-like) YP_006768905.1 1266454 R 1134782 CDS YP_006768906.1 410481360 13692122 complement(1267830..1268822) 1 NC_018650.1 COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components; glycine betaine transporter periplasmic subunit 1268822 proX 13692122 proX Escherichia coli O104:H4 str. 2009EL-2050 glycine betaine transporter periplasmic subunit YP_006768906.1 1267830 R 1134782 CDS YP_006768907.1 410481361 13692123 complement(1268879..1269943) 1 NC_018650.1 COG4176 ABC-type proline/glycine betaine transport system, permease component; glycine betaine transporter membrane protein 1269943 13692123 O3M_06205 Escherichia coli O104:H4 str. 2009EL-2050 glycine betaine transporter membrane protein YP_006768907.1 1268879 R 1134782 CDS YP_006768908.1 410481362 13692124 complement(1269936..1271138) 1 NC_018650.1 COG4175 ABC-type proline/glycine betaine transport system, ATPase component; glycine betaine transporter ATP-binding subunit 1271138 13692124 O3M_06210 Escherichia coli O104:H4 str. 2009EL-2050 glycine betaine transporter ATP-binding subunit YP_006768908.1 1269936 R 1134782 CDS YP_006768909.1 410481363 13692125 complement(1271493..1272452) 1 NC_018650.1 COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta 1272452 nrdF 13692125 nrdF Escherichia coli O104:H4 str. 2009EL-2050 ribonucleotide-diphosphate reductase subunit beta YP_006768909.1 1271493 R 1134782 CDS YP_006768910.1 410481364 13692126 complement(1272462..1274606) 1 NC_018650.1 COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha 1274606 13692126 O3M_06220 Escherichia coli O104:H4 str. 2009EL-2050 ribonucleotide-diphosphate reductase subunit alpha YP_006768910.1 1272462 R 1134782 CDS YP_006768911.1 410481365 13692127 complement(1274579..1274989) 1 NC_018650.1 COG1780 Protein involved in ribonucleotide reduction; ribonucleotide reductase stimulatory protein 1274989 nrdI 13692127 nrdI Escherichia coli O104:H4 str. 2009EL-2050 ribonucleotide reductase stimulatory protein YP_006768911.1 1274579 R 1134782 CDS YP_006768912.1 410481366 13692128 complement(1274986..1275231) 1 NC_018650.1 COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein 1275231 13692128 O3M_06230 Escherichia coli O104:H4 str. 2009EL-2050 glutaredoxin-like protein YP_006768912.1 1274986 R 1134782 CDS YP_006768913.1 410481367 13692129 complement(1275479..1275808) 1 NC_018650.1 COG4575 Uncharacterized conserved protein; hypothetical protein 1275808 13692129 O3M_06235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768913.1 1275479 R 1134782 CDS YP_006768914.1 410481368 13692130 1275960..1276304 1 NC_018650.1 hypothetical protein 1276304 13692130 O3M_06240 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768914.1 1275960 D 1134782 CDS YP_006768915.1 410481369 13692131 complement(1276341..1276790) 1 NC_018650.1 hypothetical protein 1276790 13692131 O3M_06245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768915.1 1276341 R 1134782 CDS YP_006768916.1 410481370 13692132 1277458..1277862 1 NC_018650.1 COG2916 DNA-binding protein H-NS; DNA binding protein 1277862 13692132 O3M_06250 Escherichia coli O104:H4 str. 2009EL-2050 DNA binding protein YP_006768916.1 1277458 D 1134782 CDS YP_006768917.1 410481371 13692133 complement(1277909..1278433) 1 NC_018650.1 COG0607 Rhodanese-related sulfurtransferase; inner membrane protein 1278433 13692133 O3M_06255 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006768917.1 1277909 R 1134782 CDS YP_006768918.1 410481372 13692134 complement(1278443..1278742) 1 NC_018650.1 COG0640 Predicted transcriptional regulators; DNA-binding transcriptional regulator 1278742 13692134 O3M_06260 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768918.1 1278443 R 1134782 CDS YP_006768919.1 410481373 13692135 1278925..1279083 1 NC_018650.1 COG0401 Uncharacterized homolog of Blt101; hypothetical protein 1279083 13692135 O3M_06265 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768919.1 1278925 D 1134782 CDS YP_006768920.1 410481374 13692136 1279167..1279616 1 NC_018650.1 COG1652 Uncharacterized protein containing LysM domain; LysM domain/BON superfamily protein 1279616 13692136 O3M_06270 Escherichia coli O104:H4 str. 2009EL-2050 LysM domain/BON superfamily protein YP_006768920.1 1279167 D 1134782 CDS YP_006768921.1 410481375 13692137 complement(1279617..1280279) 1 NC_018650.1 COG1802 Transcriptional regulators; DNA-binding transcriptional regulator CsiR 1280279 13692137 O3M_06275 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator CsiR YP_006768921.1 1279617 R 1134782 CDS YP_006768922.1 410481376 13692138 complement(1280300..1281700) 1 NC_018650.1 COG1113 Gamma-aminobutyrate permease and related permeases; gamma-aminobutyrate transporter 1281700 13692138 O3M_06280 Escherichia coli O104:H4 str. 2009EL-2050 gamma-aminobutyrate transporter YP_006768922.1 1280300 R 1134782 CDS YP_006768923.1 410481377 13692139 complement(1282011..1283291) 1 NC_018650.1 COG0160 4-aminobutyrate aminotransferase and related aminotransferases; 4-aminobutyrate aminotransferase 1283291 13692139 O3M_06285 Escherichia coli O104:H4 str. 2009EL-2050 4-aminobutyrate aminotransferase YP_006768923.1 1282011 R 1134782 CDS YP_006768924.1 410481378 13692140 complement(1283305..1284753) 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; succinate-semialdehyde dehydrogenase I 1284753 gabD 13692140 gabD Escherichia coli O104:H4 str. 2009EL-2050 succinate-semialdehyde dehydrogenase I YP_006768924.1 1283305 R 1134782 CDS YP_006768925.1 410481379 13692141 complement(1284776..1286044) 1 NC_018650.1 COG0579 Predicted dehydrogenase; hydroxyglutarate oxidase 1286044 13692141 O3M_06295 Escherichia coli O104:H4 str. 2009EL-2050 hydroxyglutarate oxidase YP_006768925.1 1284776 R 1134782 CDS YP_006768926.1 410481380 13692142 complement(1286064..1287041) 1 NC_018650.1 carbon starvation induced protein 1287041 13692142 O3M_06300 Escherichia coli O104:H4 str. 2009EL-2050 carbon starvation induced protein YP_006768926.1 1286064 R 1134782 CDS YP_006768927.1 410481381 13692143 complement(1287377..1287649) 1 NC_018650.1 hypothetical protein 1287649 13692143 O3M_06305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768927.1 1287377 R 1134782 CDS YP_006768928.1 410481382 13692144 complement(1287984..1289279) 1 NC_018650.1 COG0366 Glycosidases; alpha-amylase 1289279 13692144 O3M_06310 Escherichia coli O104:H4 str. 2009EL-2050 alpha-amylase YP_006768928.1 1287984 R 1134782 CDS YP_006768929.1 410481383 13692146 complement(1293740..1294486) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; IS602 transposase OrfB 1294486 13692146 O3M_06330 Escherichia coli O104:H4 str. 2009EL-2050 IS602 transposase OrfB YP_006768929.1 1293740 R 1134782 CDS YP_006768930.1 410481384 13692147 complement(1294606..1294953) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS602 transposase OrfA 1294953 13692147 O3M_06335 Escherichia coli O104:H4 str. 2009EL-2050 IS602 transposase OrfA YP_006768930.1 1294606 R 1134782 CDS YP_006768931.1 410481385 13692148 complement(1295439..1295678) 1 NC_018650.1 COG3311 Predicted transcriptional regulator; phage transcriptional regulator AlpA 1295678 13692148 O3M_06345 Escherichia coli O104:H4 str. 2009EL-2050 phage transcriptional regulator AlpA YP_006768931.1 1295439 R 1134782 CDS YP_006768932.1 410481386 13692149 1295792..1296673 1 NC_018650.1 hypothetical protein 1296673 13692149 O3M_06350 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768932.1 1295792 D 1134782 CDS YP_006768933.1 410481387 13692150 complement(1296941..1297120) 1 NC_018650.1 hypothetical protein 1297120 13692150 O3M_06355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768933.1 1296941 R 1134782 CDS YP_006768934.1 410481388 13692232 complement(1297107..1297853) 1 NC_018650.1 hypothetical protein 1297853 13692232 O3M_06360 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768934.1 1297107 R 1134782 CDS YP_006768935.1 410481389 13692233 complement(1297899..1301750) 1 NC_018650.1 COG2925 Exonuclease I; hypothetical protein 1301750 13692233 O3M_06365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768935.1 1297899 R 1134782 CDS YP_006768936.1 410481390 13692234 1302218..1305964 1 NC_018650.1 hypothetical protein 1305964 13692234 O3M_06370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768936.1 1302218 D 1134782 CDS YP_006768937.1 410481391 13692235 complement(1306103..1307344) 1 NC_018650.1 COG0582 Integrase; integrase 1307344 13692235 O3M_06375 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006768937.1 1306103 R 1134782 CDS YP_006768938.1 410481392 13692236 complement(1308127..1308609) 1 NC_018650.1 COG0691 tmRNA-binding protein; ssrA-binding protein 1308609 smpB 13692236 smpB Escherichia coli O104:H4 str. 2009EL-2050 ssrA-binding protein YP_006768938.1 1308127 R 1134782 CDS YP_006768939.1 410481393 13692237 1308780..1309217 1 NC_018650.1 COG2867 Oligoketide cyclase/lipid transport protein; hypothetical protein 1309217 13692237 O3M_06385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768939.1 1308780 D 1134782 CDS YP_006768940.1 410481394 13692238 1309207..1309497 1 NC_018650.1 COG2914 Uncharacterized protein conserved in bacteria; hypothetical protein 1309497 13692238 O3M_06390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768940.1 1309207 D 1134782 CDS YP_006768941.1 410481395 13692239 complement(1309559..1309900) 1 NC_018650.1 COG2913 Small protein A (tmRNA-binding); outer membrane biogenesis protein BamE 1309900 13692239 O3M_06395 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane biogenesis protein BamE YP_006768941.1 1309559 R 1134782 CDS YP_006768942.1 410481396 13692240 complement(1310049..1311710) 1 NC_018650.1 COG0497 ATPase involved in DNA repair; recombination and repair protein 1311710 13692240 O3M_06400 Escherichia coli O104:H4 str. 2009EL-2050 recombination and repair protein YP_006768942.1 1310049 R 1134782 CDS YP_006768943.1 410481397 13692241 complement(1311796..1312674) 1 NC_018650.1 COG0061 Predicted sugar kinase; inorganic polyphosphate/ATP-NAD kinase 1312674 13692241 O3M_06405 Escherichia coli O104:H4 str. 2009EL-2050 inorganic polyphosphate/ATP-NAD kinase YP_006768943.1 1311796 R 1134782 CDS YP_006768944.1 410481398 13692242 1312797..1313390 1 NC_018650.1 COG0576 Molecular chaperone GrpE (heat shock protein); heat shock protein HSP70 cofactor 1313390 13692242 O3M_06410 Escherichia coli O104:H4 str. 2009EL-2050 heat shock protein HSP70 cofactor YP_006768944.1 1312797 D 1134782 CDS YP_006768945.1 410481399 13692243 complement(1313445..1314641) 1 NC_018650.1 COG4536 Putative Mg2+ and Co2+ transporter CorB; hypothetical protein 1314641 13692243 O3M_06415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768945.1 1313445 R 1134782 CDS YP_006768946.1 410481400 13692244 complement(1314752..1315543) 1 NC_018650.1 COG4137 ABC-type uncharacterized transport system, permease component; hypothetical protein 1315543 13692244 O3M_06420 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768946.1 1314752 R 1134782 CDS YP_006768947.1 410481401 13692245 1315710..1317071 1 NC_018650.1 COG0541 Signal recognition particle GTPase; signal recognition particle protein 1317071 13692245 O3M_06425 Escherichia coli O104:H4 str. 2009EL-2050 signal recognition particle protein YP_006768947.1 1315710 D 1134782 CDS YP_006768948.1 410481402 13692246 1317208..1317456 1 NC_018650.1 COG0228 Ribosomal protein S16; 30S ribosomal protein S16 1317456 rpsP 13692246 rpsP Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S16 YP_006768948.1 1317208 D 1134782 CDS YP_006768949.1 410481403 13692247 1317475..1318023 1 NC_018650.1 COG0806 RimM protein, required for 16S rRNA processing; 16S rRNA-processing protein RimM 1318023 rimM 13692247 rimM Escherichia coli O104:H4 str. 2009EL-2050 16S rRNA-processing protein RimM YP_006768949.1 1317475 D 1134782 CDS YP_006768950.1 410481404 13692248 1318054..1318821 1 NC_018650.1 COG0336 tRNA-(guanine-N1)-methyltransferase; tRNA (guanine-N(1)-)-methyltransferase 1318821 trmD 13692248 trmD Escherichia coli O104:H4 str. 2009EL-2050 tRNA (guanine-N(1)-)-methyltransferase YP_006768950.1 1318054 D 1134782 CDS YP_006768951.1 410481405 13692249 1318863..1319210 1 NC_018650.1 COG0335 Ribosomal protein L19; 50S ribosomal protein L19 1319210 rplS 13692249 rplS Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L19 YP_006768951.1 1318863 D 1134782 CDS YP_006768952.1 410481406 13692250 complement(1319287..1319769) 1 NC_018650.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; outer membrane lipoprotein 1319769 13692250 O3M_06450 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006768952.1 1319287 R 1134782 CDS YP_006768953.1 410481407 13692251 complement(1319785..1321011) 1 NC_018650.1 COG2199 FOG: GGDEF domain; inner membrane diguanylate cyclase 1321011 13692251 O3M_06455 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane diguanylate cyclase YP_006768953.1 1319785 R 1134782 CDS YP_006768954.1 410481408 13692252 complement(1321001..1321519) 1 NC_018650.1 hypothetical protein 1321519 13692252 O3M_06460 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768954.1 1321001 R 1134782 CDS YP_006768955.1 410481409 13692253 complement(1321669..1322034) 1 NC_018650.1 COG0178 Excinuclease ATPase subunit; lipoprotein 1322034 13692253 O3M_06465 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006768955.1 1321669 R 1134782 CDS YP_006768956.1 410481410 13692254 1322244..1323314 1 NC_018650.1 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase 1323314 13692254 O3M_06470 Escherichia coli O104:H4 str. 2009EL-2050 phospho-2-dehydro-3-deoxyheptonate aldolase YP_006768956.1 1322244 D 1134782 CDS YP_006768957.1 410481411 13692255 1323325..1324446 1 NC_018650.1 COG1605 Chorismate mutase; bifunctional chorismate mutase/prephenate dehydrogenase 1324446 tyrA 13692255 tyrA Escherichia coli O104:H4 str. 2009EL-2050 bifunctional chorismate mutase/prephenate dehydrogenase YP_006768957.1 1323325 D 1134782 CDS YP_006768958.1 410481412 13692256 complement(1324489..1325649) 1 NC_018650.1 COG1605 Chorismate mutase; bifunctional chorismate mutase/prephenate dehydratase 1325649 pheA 13692256 pheA Escherichia coli O104:H4 str. 2009EL-2050 bifunctional chorismate mutase/prephenate dehydratase YP_006768958.1 1324489 R 1134782 CDS YP_006768959.1 410481413 13692257 complement(1325899..1326240) 1 NC_018650.1 COG1544 Ribosome-associated protein Y (PSrp-1); translation inhibitor protein RaiA 1326240 13692257 O3M_06485 Escherichia coli O104:H4 str. 2009EL-2050 translation inhibitor protein RaiA YP_006768959.1 1325899 R 1134782 CDS YP_006768960.1 410481414 13692258 complement(1326511..1327248) 1 NC_018650.1 COG4105 DNA uptake lipoprotein; outer membrane biogenesis protein BamD 1327248 13692258 O3M_06490 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane biogenesis protein BamD YP_006768960.1 1326511 R 1134782 CDS YP_006768961.1 410481415 13692259 1327383..1328363 1 NC_018650.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA pseudouridine synthase D 1328363 rluD 13692259 rluD Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA pseudouridine synthase D YP_006768961.1 1327383 D 1134782 CDS YP_006768962.1 410481416 13692260 1328360..1329091 1 NC_018650.1 COG1496 Uncharacterized conserved protein; hypothetical protein 1329091 13692260 O3M_06500 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768962.1 1328360 D 1134782 CDS YP_006768963.1 410481417 13692261 1329221..1331794 1 NC_018650.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; protein disaggregation chaperone 1331794 13692261 O3M_06505 Escherichia coli O104:H4 str. 2009EL-2050 protein disaggregation chaperone YP_006768963.1 1329221 D 1134782 CDS YP_006768964.1 410481418 13692266 1337662..1338960 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; alpha-ketoglutarate transporter 1338960 13692266 O3M_06510 Escherichia coli O104:H4 str. 2009EL-2050 alpha-ketoglutarate transporter YP_006768964.1 1337662 D 1134782 CDS YP_006768965.1 410481419 13692267 complement(1338957..1339280) 1 NC_018650.1 COG5544 Predicted periplasmic lipoprotein; lipoprotein 1339280 13692267 O3M_06515 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006768965.1 1338957 R 1134782 CDS YP_006768966.1 410481420 13692268 complement(1339326..1340681) 1 NC_018650.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phosphatidylserine synthase 1340681 pssA 13692268 pssA Escherichia coli O104:H4 str. 2009EL-2050 phosphatidylserine synthase YP_006768966.1 1339326 R 1134782 CDS YP_006768967.1 410481421 13692269 complement(1340795..1343455) 1 NC_018650.1 ATP-binding subunit; COG1042 Acyl-CoA synthetase (NDP forming); acyl-CoA synthetase NAD(P)-binding subunit 1343455 13692269 O3M_06525 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA synthetase NAD(P)-binding subunit YP_006768967.1 1340795 R 1134782 CDS YP_006768968.1 410481422 13692270 complement(1343487..1344185) 1 NC_018650.1 COG3148 Uncharacterized conserved protein; DTW domain-containing protein yfiP 1344185 13692270 O3M_06530 Escherichia coli O104:H4 str. 2009EL-2050 DTW domain-containing protein yfiP YP_006768968.1 1343487 R 1134782 CDS YP_006768969.1 410481423 13692271 complement(1344254..1344673) 1 NC_018650.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 2 1344673 13692271 O3M_06535 Escherichia coli O104:H4 str. 2009EL-2050 thioredoxin 2 YP_006768969.1 1344254 R 1134782 CDS YP_006768970.1 410481424 13692272 1344880..1345917 1 NC_018650.1 COG0566 rRNA methylases; methyltransferase 1345917 13692272 O3M_06540 Escherichia coli O104:H4 str. 2009EL-2050 methyltransferase YP_006768970.1 1344880 D 1134782 CDS YP_006768971.1 410481425 13692273 complement(1345965..1346654) 1 NC_018650.1 COG0692 Uracil DNA glycosylase; uracil-DNA glycosylase 1346654 13692273 O3M_06545 Escherichia coli O104:H4 str. 2009EL-2050 uracil-DNA glycosylase YP_006768971.1 1345965 R 1134782 CDS YP_006768972.1 410481426 13692274 1346959..1347342 1 NC_018650.1 COG3445 Acid-induced glycyl radical enzyme; autonomous glycyl radical cofactor GrcA 1347342 13692274 O3M_06550 Escherichia coli O104:H4 str. 2009EL-2050 autonomous glycyl radical cofactor GrcA YP_006768972.1 1346959 D 1134782 CDS YP_006768973.1 410481427 13692275 complement(1347397..1347984) 1 NC_018650.1 COG1280 Putative threonine efflux protein; cysteine/O-acetylserine exporter 1347984 13692275 O3M_06555 Escherichia coli O104:H4 str. 2009EL-2050 cysteine/O-acetylserine exporter YP_006768973.1 1347397 R 1134782 CDS YP_006768974.1 410481428 13692276 1348087..1348968 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 1348968 13692276 O3M_06560 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006768974.1 1348087 D 1134782 CDS YP_006768975.1 410481429 13692277 complement(1349019..1349171) 1 NC_018650.1 hypothetical protein 1349171 13692277 O3M_06565 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768975.1 1349019 R 1134782 CDS YP_006768976.1 410481430 13692278 complement(1349177..1350511) 1 NC_018650.1 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase SrmB 1350511 13692278 O3M_06570 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent RNA helicase SrmB YP_006768976.1 1349177 R 1134782 CDS YP_006768977.1 410481431 13692279 1350643..1351380 1 NC_018650.1 COG4123 Predicted O-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase 1351380 13692279 O3M_06575 Escherichia coli O104:H4 str. 2009EL-2050 S-adenosyl-L-methionine-dependent methyltransferase YP_006768977.1 1350643 D 1134782 CDS YP_006768978.1 410481432 13692280 complement(1351365..1352987) 1 NC_018650.1 COG0029 Aspartate oxidase; L-aspartate oxidase 1352987 13692280 O3M_06580 Escherichia coli O104:H4 str. 2009EL-2050 L-aspartate oxidase YP_006768978.1 1351365 R 1134782 CDS YP_006768979.1 410481433 13692281 1353243..1353398 1 NC_018650.1 hypothetical protein 1353398 13692281 O3M_06585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768979.1 1353243 D 1134782 CDS YP_006768980.1 410481434 13692282 1353395..1353970 1 NC_018650.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor RpoE 1353970 13692282 O3M_06590 Escherichia coli O104:H4 str. 2009EL-2050 RNA polymerase sigma factor RpoE YP_006768980.1 1353395 D 1134782 CDS YP_006768981.1 410481435 13692283 1354003..1354653 1 NC_018650.1 COG3073 Negative regulator of sigma E activity; anti-RNA polymerase sigma factor SigE 1354653 13692283 O3M_06595 Escherichia coli O104:H4 str. 2009EL-2050 anti-RNA polymerase sigma factor SigE YP_006768981.1 1354003 D 1134782 CDS YP_006768982.1 410481436 13692284 1354653..1355609 1 NC_018650.1 COG3026 Negative regulator of sigma E activity; anti-sigma E factor 1355609 rseB 13692284 rseB Escherichia coli O104:H4 str. 2009EL-2050 anti-sigma E factor YP_006768982.1 1354653 D 1134782 CDS YP_006768983.1 410481437 13692285 1355606..1356085 1 NC_018650.1 COG3086 Positive regulator of sigma E activity; SoxR reducing system protein RseC 1356085 13692285 O3M_06605 Escherichia coli O104:H4 str. 2009EL-2050 SoxR reducing system protein RseC YP_006768983.1 1355606 D 1134782 CDS YP_006768984.1 410481438 13692286 1356283..1358082 1 NC_018650.1 COG0481 Membrane GTPase LepA; GTP-binding protein LepA 1358082 13692286 O3M_06610 Escherichia coli O104:H4 str. 2009EL-2050 GTP-binding protein LepA YP_006768984.1 1356283 D 1134782 CDS YP_006768985.1 410481439 13692287 1358098..1359072 1 NC_018650.1 COG0681 Signal peptidase I; signal peptidase I 1359072 13692287 O3M_06615 Escherichia coli O104:H4 str. 2009EL-2050 signal peptidase I YP_006768985.1 1358098 D 1134782 CDS YP_006768986.1 410481440 13692288 1359345..1360025 1 NC_018650.1 COG0571 dsRNA-specific ribonuclease; ribonuclease III 1360025 rnc 13692288 rnc Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease III YP_006768986.1 1359345 D 1134782 CDS YP_006768987.1 410481441 13692289 1360022..1360927 1 NC_018650.1 COG1159 GTPase; GTPase Era 1360927 era 13692289 era Escherichia coli O104:H4 str. 2009EL-2050 GTPase Era YP_006768987.1 1360022 D 1134782 CDS YP_006768988.1 410481442 13692290 1360939..1361667 1 NC_018650.1 COG1381 Recombinational DNA repair protein (RecF pathway); DNA repair protein RecO 1361667 recO 13692290 recO Escherichia coli O104:H4 str. 2009EL-2050 DNA repair protein RecO YP_006768988.1 1360939 D 1134782 CDS YP_006768989.1 410481443 13692291 1361679..1362410 1 NC_018650.1 COG0854 Pyridoxal phosphate biosynthesis protein; pyridoxine 5'-phosphate synthase 1362410 13692291 O3M_06635 Escherichia coli O104:H4 str. 2009EL-2050 pyridoxine 5'-phosphate synthase YP_006768989.1 1361679 D 1134782 CDS YP_006768990.1 410481444 13692292 1362410..1362790 1 NC_018650.1 COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); 4'-phosphopantetheinyl transferase 1362790 acpS 13692292 acpS Escherichia coli O104:H4 str. 2009EL-2050 4'-phosphopantetheinyl transferase YP_006768990.1 1362410 D 1134782 CDS YP_006768991.1 410481445 13692293 1363210..1363290 1 NC_018650.1 toxic membrane protein 1363290 13692293 O3M_06645 Escherichia coli O104:H4 str. 2009EL-2050 toxic membrane protein YP_006768991.1 1363210 D 1134782 CDS YP_006768992.1 410481446 13692294 complement(1363484..1363744) 1 NC_018650.1 COG1145 Ferredoxin; 4Fe-4S binding protein 1363744 13692294 O3M_06650 Escherichia coli O104:H4 str. 2009EL-2050 4Fe-4S binding protein YP_006768992.1 1363484 R 1134782 CDS YP_006768993.1 410481447 13692295 complement(1363800..1364648) 1 NC_018650.1 COG1737 Transcriptional regulators; DNA-binding transcriptional regulator 1364648 13692295 O3M_06655 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006768993.1 1363800 R 1134782 CDS YP_006768994.1 410481448 13692296 1364857..1365492 1 NC_018650.1 COG0560 Phosphoserine phosphatase; hypothetical protein 1365492 13692296 O3M_06660 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768994.1 1364857 D 1134782 CDS YP_006768995.1 410481449 13692297 1365517..1366053 1 NC_018650.1 COG0590 Cytosine/adenosine deaminases; tRNA-specific adenosine deaminase 1366053 13692297 O3M_06665 Escherichia coli O104:H4 str. 2009EL-2050 tRNA-specific adenosine deaminase YP_006768995.1 1365517 D 1134782 CDS YP_006768996.1 410481450 13692298 complement(1366050..1367606) 1 NC_018650.1 COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein; membrane-bound lytic transglycosylase F 1367606 13692298 O3M_06670 Escherichia coli O104:H4 str. 2009EL-2050 membrane-bound lytic transglycosylase F YP_006768996.1 1366050 R 1134782 CDS YP_006768997.1 410481451 13692299 1367867..1371751 1 NC_018650.1 COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine synthase 1371751 13692299 O3M_06675 Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylformylglycinamidine synthase YP_006768997.1 1367867 D 1134782 CDS YP_006768998.1 410481452 13692300 1372327..1373754 1 NC_018650.1 COG0642 Signal transduction histidine kinase; 2-component sensor protein 1373754 13692300 O3M_06680 Escherichia coli O104:H4 str. 2009EL-2050 2-component sensor protein YP_006768998.1 1372327 D 1134782 CDS YP_006768999.1 410481453 13692301 1373919..1374632 1 NC_018650.1 hypothetical protein 1374632 13692301 O3M_06685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006768999.1 1373919 D 1134782 CDS YP_006769000.1 410481454 13692302 1374622..1375956 1 NC_018650.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; response regulator GlrR 1375956 13692302 O3M_06690 Escherichia coli O104:H4 str. 2009EL-2050 response regulator GlrR YP_006769000.1 1374622 D 1134782 CDS YP_006769001.1 410481455 13692303 1376017..1376355 1 NC_018650.1 COG0347 Nitrogen regulatory protein PII; nitrogen regulatory protein P-II 1 1376355 13692303 O3M_06695 Escherichia coli O104:H4 str. 2009EL-2050 nitrogen regulatory protein P-II 1 YP_006769001.1 1376017 D 1134782 CDS YP_006769002.1 410481456 13692304 complement(1376400..1377590) 1 NC_018650.1 COG1017 Hemoglobin-like flavoprotein; bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2 1377590 13692304 O3M_06700 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2 YP_006769002.1 1376400 R 1134782 CDS YP_006769003.1 410481457 13692305 1377918..1379171 1 NC_018650.1 COG0112 Glycine/serine hydroxymethyltransferase; serine hydroxymethyltransferase 1379171 glyA 13692305 glyA Escherichia coli O104:H4 str. 2009EL-2050 serine hydroxymethyltransferase YP_006769003.1 1377918 D 1134782 CDS YP_006769004.1 410481458 13692306 complement(1379235..1380428) 1 NC_018650.1 COG1940 Transcriptional regulator/sugar kinase; DNA-binding transcriptional regulator 1380428 13692306 O3M_06710 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006769004.1 1379235 R 1134782 CDS YP_006769005.1 410481459 13692307 1380546..1383827 1 NC_018650.1 COG0457 FOG: TPR repeat; hypothetical protein 1383827 13692307 O3M_06715 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769005.1 1380546 D 1134782 CDS YP_006769006.1 410481460 13692308 1383924..1384907 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; sugar ABC transporter substrate-binding protein 1384907 13692308 O3M_06720 Escherichia coli O104:H4 str. 2009EL-2050 sugar ABC transporter substrate-binding protein YP_006769006.1 1383924 D 1134782 CDS YP_006769007.1 410481461 13692309 1384930..1386441 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein 1386441 13692309 O3M_06725 Escherichia coli O104:H4 str. 2009EL-2050 sugar ABC transporter ATP-binding protein YP_006769007.1 1384930 D 1134782 CDS YP_006769008.1 410481462 13692310 1386466..1387464 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar transporter subunit 1387464 13692310 O3M_06730 Escherichia coli O104:H4 str. 2009EL-2050 sugar transporter subunit YP_006769008.1 1386466 D 1134782 CDS YP_006769009.1 410481463 13692311 1387530..1388591 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein 1388591 13692311 O3M_06735 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase, Zn-dependent and NAD(P)-binding protein YP_006769009.1 1387530 D 1134782 CDS YP_006769010.1 410481464 13692312 1388603..1389475 1 NC_018650.1 COG2017 Galactose mutarotase and related enzymes; hypothetical protein 1389475 13692312 O3M_06740 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769010.1 1388603 D 1134782 CDS YP_006769011.1 410481465 13692394 complement(1389523..1389945) 1 NC_018650.1 COG2259 Predicted membrane protein; inner membrane protein 1389945 13692394 O3M_06745 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769011.1 1389523 R 1134782 CDS YP_006769012.1 410481466 13692395 complement(1390042..1391244) 1 NC_018650.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; phenylpropionate dioxygenase ferredoxin reductase subunit 1391244 13692395 O3M_06750 Escherichia coli O104:H4 str. 2009EL-2050 phenylpropionate dioxygenase ferredoxin reductase subunit YP_006769012.1 1390042 R 1134782 CDS YP_006769013.1 410481467 13692396 complement(1391254..1392066) 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 1392066 13692396 O3M_06755 Escherichia coli O104:H4 str. 2009EL-2050 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_006769013.1 1391254 R 1134782 CDS YP_006769014.1 410481468 13692397 complement(1392063..1392383) 1 NC_018650.1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; 3-phenylpropionate dioxygenase ferredoxin subunit 1392383 13692397 O3M_06760 Escherichia coli O104:H4 str. 2009EL-2050 3-phenylpropionate dioxygenase ferredoxin subunit YP_006769014.1 1392063 R 1134782 CDS YP_006769015.1 410481469 13692398 complement(1392383..1392901) 1 NC_018650.1 COG5517 Small subunit of phenylpropionate dioxygenase; 3-phenylpropionate dioxygenase subunit beta 1392901 13692398 O3M_06765 Escherichia coli O104:H4 str. 2009EL-2050 3-phenylpropionate dioxygenase subunit beta YP_006769015.1 1392383 R 1134782 CDS YP_006769016.1 410481470 13692399 complement(1392898..1394259) 1 NC_018650.1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha 1394259 13692399 O3M_06770 Escherichia coli O104:H4 str. 2009EL-2050 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha YP_006769016.1 1392898 R 1134782 CDS YP_006769017.1 410481471 13692400 1394395..1395285 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator HcaR 1395285 13692400 O3M_06775 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator HcaR YP_006769017.1 1394395 D 1134782 CDS YP_006769018.1 410481472 13692401 1395445..1396584 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; 3-phenylpropionic acid transporter 1396584 13692401 O3M_06780 Escherichia coli O104:H4 str. 2009EL-2050 3-phenylpropionic acid transporter YP_006769018.1 1395445 D 1134782 CDS YP_006769019.1 410481473 13692402 complement(1396576..1397856) 1 NC_018650.1 COG3711 Transcriptional antiterminator; stationary phase inducible protein CsiE 1397856 13692402 O3M_06785 Escherichia coli O104:H4 str. 2009EL-2050 stationary phase inducible protein CsiE YP_006769019.1 1396576 R 1134782 CDS YP_006769020.1 410481474 13692403 complement(1398047..1398901) 1 NC_018650.1 COG1073 Hydrolases of the alpha/beta superfamily; peptidase 1398901 13692403 O3M_06790 Escherichia coli O104:H4 str. 2009EL-2050 peptidase YP_006769020.1 1398047 R 1134782 CDS YP_006769021.1 410481475 13692404 complement(1399046..1399849) 1 NC_018650.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; inositol monophosphatase 1399849 13692404 O3M_06795 Escherichia coli O104:H4 str. 2009EL-2050 inositol monophosphatase YP_006769021.1 1399046 R 1134782 CDS YP_006769022.1 410481476 13692405 1399968..1400708 1 NC_018650.1 COG0565 rRNA methylase; tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ 1400708 13692405 O3M_06800 Escherichia coli O104:H4 str. 2009EL-2050 tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ YP_006769022.1 1399968 D 1134782 CDS YP_006769023.1 410481477 13692406 1400978..1401466 1 NC_018650.1 COG1959 Predicted transcriptional regulator; DNA-binding transcriptional regulator IscR 1401466 13692406 O3M_06805 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator IscR YP_006769023.1 1400978 D 1134782 CDS YP_006769024.1 410481478 13692407 1401578..1402792 1 NC_018650.1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine desulfurase 1402792 13692407 O3M_06810 Escherichia coli O104:H4 str. 2009EL-2050 cysteine desulfurase YP_006769024.1 1401578 D 1134782 CDS YP_006769025.1 410481479 13692408 1402820..1403206 1 NC_018650.1 COG0822 NifU homolog involved in Fe-S cluster formation; scaffold protein 1403206 13692408 O3M_06815 Escherichia coli O104:H4 str. 2009EL-2050 scaffold protein YP_006769025.1 1402820 D 1134782 CDS YP_006769026.1 410481480 13692409 1403223..1403546 1 NC_018650.1 COG0316 Uncharacterized conserved protein; iron-sulfur cluster assembly protein 1403546 iscA 13692409 iscA Escherichia coli O104:H4 str. 2009EL-2050 iron-sulfur cluster assembly protein YP_006769026.1 1403223 D 1134782 CDS YP_006769027.1 410481481 13692410 1403642..1404157 1 NC_018650.1 COG1076 DnaJ-domain-containing proteins 1; co-chaperone HscB 1404157 hscB 13692410 hscB Escherichia coli O104:H4 str. 2009EL-2050 co-chaperone HscB YP_006769027.1 1403642 D 1134782 CDS YP_006769028.1 410481482 13692411 1404174..1406024 1 NC_018650.1 COG0443 Molecular chaperone; chaperone protein HscA 1406024 hscA 13692411 hscA Escherichia coli O104:H4 str. 2009EL-2050 chaperone protein HscA YP_006769028.1 1404174 D 1134782 CDS YP_006769029.1 410481483 13692412 1406026..1406361 1 NC_018650.1 COG0633 Ferredoxin; 2Fe-2S ferredoxin 1406361 13692412 O3M_06835 Escherichia coli O104:H4 str. 2009EL-2050 2Fe-2S ferredoxin YP_006769029.1 1406026 D 1134782 CDS YP_006769030.1 410481484 13692413 1406373..1406573 1 NC_018650.1 COG2975 Uncharacterized protein conserved in bacteria; hypothetical protein 1406573 13692413 O3M_06840 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769030.1 1406373 D 1134782 CDS YP_006769031.1 410481485 13692414 1406751..1408034 1 NC_018650.1 COG0260 Leucyl aminopeptidase; aminopeptidase B 1408034 13692414 O3M_06845 Escherichia coli O104:H4 str. 2009EL-2050 aminopeptidase B YP_006769031.1 1406751 D 1134782 CDS YP_006769032.1 410481486 13692415 1408176..1408952 1 NC_018650.1 enhanced serine sensitivity protein SseB 1408952 13692415 O3M_06850 Escherichia coli O104:H4 str. 2009EL-2050 enhanced serine sensitivity protein SseB YP_006769032.1 1408176 D 1134782 CDS YP_006769033.1 410481487 13692416 complement(1409445..1410290) 1 NC_018650.1 COG2897 Rhodanese-related sulfurtransferase; 3-mercaptopyruvate sulfurtransferase 1410290 sseA 13692416 sseA Escherichia coli O104:H4 str. 2009EL-2050 3-mercaptopyruvate sulfurtransferase YP_006769033.1 1409445 R 1134782 CDS YP_006769034.1 410481488 13692417 1410497..1415458 1 NC_018650.1 COG2373 Large extracellular alpha-helical protein; hypothetical protein 1415458 13692417 O3M_06860 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769034.1 1410497 D 1134782 CDS YP_006769035.1 410481489 13692418 1415459..1417771 1 NC_018650.1 COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; penicillin-binding protein 1C 1417771 13692418 O3M_06865 Escherichia coli O104:H4 str. 2009EL-2050 penicillin-binding protein 1C YP_006769035.1 1415459 D 1134782 CDS YP_006769036.1 410481490 13692419 1417920..1418351 1 NC_018650.1 COG0105 Nucleoside diphosphate kinase; mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase 1418351 ndk 13692419 ndk Escherichia coli O104:H4 str. 2009EL-2050 mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase YP_006769036.1 1417920 D 1134782 CDS YP_006769037.1 410481491 13692420 1418501..1419655 1 NC_018650.1 COG0820 Predicted Fe-S-cluster redox enzyme; ribosomal RNA large subunit methyltransferase N 1419655 13692420 O3M_06875 Escherichia coli O104:H4 str. 2009EL-2050 ribosomal RNA large subunit methyltransferase N YP_006769037.1 1418501 D 1134782 CDS YP_006769038.1 410481492 13692421 1419940..1420953 1 NC_018650.1 COG1426 Uncharacterized protein conserved in bacteria; cytoskeletal protein RodZ 1420953 13692421 O3M_06880 Escherichia coli O104:H4 str. 2009EL-2050 cytoskeletal protein RodZ YP_006769038.1 1419940 D 1134782 CDS YP_006769039.1 410481493 13692422 1420980..1422098 1 NC_018650.1 COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1422098 ispG 13692422 ispG Escherichia coli O104:H4 str. 2009EL-2050 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_006769039.1 1420980 D 1134782 CDS YP_006769040.1 410481494 13692423 1422209..1423483 1 NC_018650.1 COG0124 Histidyl-tRNA synthetase; histidyl-tRNA synthetase 1423483 hisS 13692423 hisS Escherichia coli O104:H4 str. 2009EL-2050 histidyl-tRNA synthetase YP_006769040.1 1422209 D 1134782 CDS YP_006769041.1 410481495 13692424 1423501..1424121 1 NC_018650.1 COG2976 Uncharacterized protein conserved in bacteria; hypothetical protein 1424121 13692424 O3M_06895 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769041.1 1423501 D 1134782 CDS YP_006769042.1 410481496 13692425 1424132..1425310 1 NC_018650.1 COG1520 FOG: WD40-like repeat; outer membrane biogenesis protein BamB 1425310 13692425 O3M_06900 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane biogenesis protein BamB YP_006769042.1 1424132 D 1134782 CDS YP_006769043.1 410481497 13692426 1425428..1426900 1 NC_018650.1 COG1160 Predicted GTPases; GTP-binding protein Der 1426900 13692426 O3M_06905 Escherichia coli O104:H4 str. 2009EL-2050 GTP-binding protein Der YP_006769043.1 1425428 D 1134782 CDS YP_006769044.1 410481498 13692427 1426969..1427184 1 NC_018650.1 COG1933 Archaeal DNA polymerase II, large subunit; hypothetical protein 1427184 13692427 O3M_06910 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769044.1 1426969 D 1134782 CDS YP_006769045.1 410481499 13692428 complement(1427181..1428551) 1 NC_018650.1 COG1570 Exonuclease VII, large subunit; exodeoxyribonuclease VII large subunit 1428551 xseA 13692428 xseA Escherichia coli O104:H4 str. 2009EL-2050 exodeoxyribonuclease VII large subunit YP_006769045.1 1427181 R 1134782 CDS YP_006769046.1 410481500 13692429 1428713..1430179 1 NC_018650.1 COG0516 IMP dehydrogenase/GMP reductase; inosine 5'-monophosphate dehydrogenase 1430179 13692429 O3M_06920 Escherichia coli O104:H4 str. 2009EL-2050 inosine 5'-monophosphate dehydrogenase YP_006769046.1 1428713 D 1134782 CDS YP_006769047.1 410481501 13692430 1430248..1431825 1 NC_018650.1 COG0518 GMP synthase - Glutamine amidotransferase domain; GMP synthase 1431825 guaA 13692430 guaA Escherichia coli O104:H4 str. 2009EL-2050 GMP synthase YP_006769047.1 1430248 D 1134782 CDS YP_006769048.1 410481502 13692431 complement(1431918..1432457) 1 NC_018650.1 hypothetical protein 1432457 13692431 O3M_06930 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769048.1 1431918 R 1134782 CDS YP_006769049.1 410481503 13692432 complement(1432473..1432991) 1 NC_018650.1 outer membrane lipoprotein 1432991 13692432 O3M_06935 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006769049.1 1432473 R 1134782 CDS YP_006769050.1 410481504 13692433 complement(1433302..1433493) 1 NC_018650.1 hypothetical protein 1433493 13692433 O3M_06940 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769050.1 1433302 R 1134782 CDS YP_006769051.1 410481505 13692434 1433511..1433663 1 NC_018650.1 hypothetical protein 1433663 13692434 O3M_06945 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769051.1 1433511 D 1134782 CDS YP_006769052.1 410481506 13692435 1433845..1436088 1 NC_018650.1 COG2199 FOG: GGDEF domain; inner membrane protein 1436088 13692435 O3M_06950 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769052.1 1433845 D 1134782 CDS YP_006769053.1 410481507 13692436 complement(1436127..1437668) 1 NC_018650.1 COG0248 Exopolyphosphatase; exopolyphosphatase 1437668 13692436 O3M_06955 Escherichia coli O104:H4 str. 2009EL-2050 exopolyphosphatase YP_006769053.1 1436127 R 1134782 CDS YP_006769054.1 410481508 13692437 complement(1437673..1439739) 1 NC_018650.1 COG0855 Polyphosphate kinase; polyphosphate kinase 1439739 13692437 O3M_06960 Escherichia coli O104:H4 str. 2009EL-2050 polyphosphate kinase YP_006769054.1 1437673 R 1134782 CDS YP_006769055.1 410481509 13692438 complement(1439910..1440548) 1 NC_018650.1 COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; phosphoribosylglycinamide formyltransferase 1440548 purN 13692438 purN Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylglycinamide formyltransferase YP_006769055.1 1439910 R 1134782 CDS YP_006769056.1 410481510 13692439 complement(1440548..1441585) 1 NC_018650.1 COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; phosphoribosylaminoimidazole synthetase 1441585 13692439 O3M_06970 Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylaminoimidazole synthetase YP_006769056.1 1440548 R 1134782 CDS YP_006769057.1 410481511 13692440 1441910..1442536 1 NC_018650.1 COG0035 Uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 1442536 upp 13692440 upp Escherichia coli O104:H4 str. 2009EL-2050 uracil phosphoribosyltransferase YP_006769057.1 1441910 D 1134782 CDS YP_006769058.1 410481512 13692441 1442622..1443911 1 NC_018650.1 COG2233 Xanthine/uracil permeases; uracil transporter 1443911 13692441 O3M_06980 Escherichia coli O104:H4 str. 2009EL-2050 uracil transporter YP_006769058.1 1442622 D 1134782 CDS YP_006769059.1 410481513 13692442 1443961..1444707 1 NC_018650.1 COG0593 ATPase involved in DNA replication initiation; DNA replication initiation factor 1444707 13692442 O3M_06985 Escherichia coli O104:H4 str. 2009EL-2050 DNA replication initiation factor YP_006769059.1 1443961 D 1134782 CDS YP_006769060.1 410481514 13692443 complement(1444845..1445204) 1 NC_018650.1 COG1393 Arsenate reductase and related proteins, glutaredoxin family; oxidoreductase 1445204 13692443 O3M_06990 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006769060.1 1444845 R 1134782 CDS YP_006769061.1 410481515 13692444 complement(1445225..1446688) 1 NC_018650.1 COG4783 Putative Zn-dependent protease, contains TPR repeats; peptidase, M48 family protein 1446688 13692444 O3M_06995 Escherichia coli O104:H4 str. 2009EL-2050 peptidase, M48 family protein YP_006769061.1 1445225 R 1134782 CDS YP_006769062.1 410481516 13692445 1446901..1447962 1 NC_018650.1 COG0628 Predicted permease; permease perM 1447962 13692445 O3M_07000 Escherichia coli O104:H4 str. 2009EL-2050 permease perM YP_006769062.1 1446901 D 1134782 CDS YP_006769063.1 410481517 13692446 complement(1448116..1448847) 1 NC_018650.1 COG2116 Formate/nitrite family of transporters; formate transporter 1448847 13692446 O3M_07005 Escherichia coli O104:H4 str. 2009EL-2050 formate transporter YP_006769063.1 1448116 R 1134782 CDS YP_006769064.1 410481518 13692447 complement(1448869..1450881) 1 NC_018650.1 COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; DNA-binding transcriptional activator, formate sensing 1450881 13692447 O3M_07010 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator, formate sensing YP_006769064.1 1448869 R 1134782 CDS YP_006769065.1 410481519 13692448 complement(1450911..1451324) 1 NC_018650.1 formate hydrogenlyase maturation protein HycH 1451324 13692448 O3M_07015 Escherichia coli O104:H4 str. 2009EL-2050 formate hydrogenlyase maturation protein HycH YP_006769065.1 1450911 R 1134782 CDS YP_006769066.1 410481520 13692449 complement(1451317..1452075) 1 NC_018650.1 COG3260 Ni,Fe-hydrogenase III small subunit; hydrogenase 4, Fe-S subunit 1452075 13692449 O3M_07020 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4, Fe-S subunit YP_006769066.1 1451317 R 1134782 CDS YP_006769067.1 410481521 13692450 complement(1452072..1452611) 1 NC_018650.1 COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); hydrogenase 4 subunit H 1452611 13692450 O3M_07025 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 subunit H YP_006769067.1 1452072 R 1134782 CDS YP_006769068.1 410481522 13692451 complement(1452621..1454336) 1 NC_018650.1 COG3262 Ni,Fe-hydrogenase III component G; hydrogenase 4 membrane subunit 1454336 13692451 O3M_07030 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 membrane subunit YP_006769068.1 1452621 R 1134782 CDS YP_006769069.1 410481523 13692452 complement(1454326..1455906) 1 NC_018650.1 COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hydrogenase 4 subunit F 1455906 13692452 O3M_07035 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 subunit F YP_006769069.1 1454326 R 1134782 CDS YP_006769070.1 410481524 13692453 complement(1455911..1456561) 1 NC_018650.1 COG4237 Hydrogenase 4 membrane component (E); hydrogenase 4 membrane subunit 1456561 hyfE 13692453 hyfE Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 membrane subunit YP_006769070.1 1455911 R 1134782 CDS YP_006769071.1 410481525 13692454 complement(1456573..1457559) 1 NC_018650.1 COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; hydrogenase 4 subunit D 1457559 13692454 O3M_07045 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 subunit D YP_006769071.1 1456573 R 1134782 CDS YP_006769072.1 410481526 13692455 complement(1457556..1458011) 1 NC_018650.1 COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; hydrogenase 4 membrane subunit 1458011 13692455 O3M_07050 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 membrane subunit YP_006769072.1 1457556 R 1134782 CDS YP_006769073.1 410481527 13692456 complement(1458028..1458162) 1 NC_018650.1 hydrogenase 4 membrane subunit 1458162 13692456 O3M_07055 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 membrane subunit YP_006769073.1 1458028 R 1134782 CDS YP_006769074.1 410481528 13692457 complement(1458217..1458975) 1 NC_018650.1 COG0650 Formate hydrogenlyase subunit 4; hydrogenase 4 membrane subunit 1458975 13692457 O3M_07060 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 membrane subunit YP_006769074.1 1458217 R 1134782 CDS YP_006769075.1 410481529 13692458 complement(1458986..1461004) 1 NC_018650.1 COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hydrogenase 4 subunit B 1461004 13692458 O3M_07065 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4 subunit B YP_006769075.1 1458986 R 1134782 CDS YP_006769076.1 410481530 13692459 complement(1461004..1461621) 1 NC_018650.1 COG1142 Fe-S-cluster-containing hydrogenase components 2; hydrogenase 4, 4Fe-4S subunit 1461621 13692459 O3M_07070 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 4, 4Fe-4S subunit YP_006769076.1 1461004 R 1134782 CDS YP_006769077.1 410481531 13692460 complement(1461874..1462344) 1 NC_018650.1 COG1225 Peroxiredoxin; thioredoxin-dependent thiol peroxidase 1462344 bcp 13692460 bcp Escherichia coli O104:H4 str. 2009EL-2050 thioredoxin-dependent thiol peroxidase YP_006769077.1 1461874 R 1134782 CDS YP_006769078.1 410481532 13692461 complement(1462344..1462916) 1 NC_018650.1 COG2716 Glycine cleavage system regulatory protein; glycine cleavage system transcriptional repressor 1462916 gcvR 13692461 gcvR Escherichia coli O104:H4 str. 2009EL-2050 glycine cleavage system transcriptional repressor YP_006769078.1 1462344 R 1134782 CDS YP_006769079.1 410481533 13692462 1463062..1463940 1 NC_018650.1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase 1463940 13692462 O3M_07085 Escherichia coli O104:H4 str. 2009EL-2050 dihydrodipicolinate synthase YP_006769079.1 1463062 D 1134782 CDS YP_006769080.1 410481534 13692463 1463957..1464991 1 NC_018650.1 COG3317 Uncharacterized lipoprotein; lipoprotein 1464991 13692463 O3M_07090 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006769080.1 1463957 D 1134782 CDS YP_006769081.1 410481535 13692464 complement(1464902..1465153) 1 NC_018650.1 hypothetical protein 1465153 13692464 O3M_07095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769081.1 1464902 R 1134782 CDS YP_006769082.1 410481536 13692465 1465204..1465917 1 NC_018650.1 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazole succinocarboxamide synthase 1465917 13692465 O3M_07100 Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylaminoimidazole succinocarboxamide synthase YP_006769082.1 1465204 D 1134782 CDS YP_006769083.1 410481537 13692466 1466072..1466299 1 NC_018650.1 COG4456 Virulence-associated protein and related proteins; transcriptional regulation protein 1466299 13692466 O3M_07105 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulation protein YP_006769083.1 1466072 D 1134782 CDS YP_006769084.1 410481538 13692467 1466299..1466697 1 NC_018650.1 COG1487 Predicted nucleic acid-binding protein, contains PIN domain; plasmid maintenance protein 1466697 13692467 O3M_07110 Escherichia coli O104:H4 str. 2009EL-2050 plasmid maintenance protein YP_006769084.1 1466299 D 1134782 CDS YP_006769085.1 410481539 13692468 1466844..1467707 1 NC_018650.1 COG2321 Predicted metalloprotease; hypothetical protein 1467707 13692468 O3M_07115 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769085.1 1466844 D 1134782 CDS YP_006769086.1 410481540 13692469 1467722..1469737 1 NC_018650.1 COG1444 Predicted P-loop ATPase fused to an acetyltransferase; hydrolase 1469737 13692469 O3M_07120 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006769086.1 1467722 D 1134782 CDS YP_006769087.1 410481541 13692470 1469811..1470509 1 NC_018650.1 COG0400 Predicted esterase; hydrolase 1470509 13692470 O3M_07125 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006769087.1 1469811 D 1134782 CDS YP_006769088.1 410481542 13692471 complement(1470619..1470819) 1 NC_018650.1 hypothetical protein 1470819 13692471 O3M_07130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769088.1 1470619 R 1134782 CDS YP_006769089.1 410481543 13692472 complement(1470847..1471974) 1 NC_018650.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; succinyl-diaminopimelate desuccinylase 1471974 13692472 O3M_07135 Escherichia coli O104:H4 str. 2009EL-2050 succinyl-diaminopimelate desuccinylase YP_006769089.1 1470847 R 1134782 CDS YP_006769090.1 410481544 13692473 complement(1471978..1472334) 1 NC_018650.1 COG1393 Arsenate reductase and related proteins, glutaredoxin family; reductase 1472334 13692473 O3M_07140 Escherichia coli O104:H4 str. 2009EL-2050 reductase YP_006769090.1 1471978 R 1134782 CDS YP_006769091.1 410481545 13692474 complement(1472873..1475986) 1 NC_018650.1 COG0841 Cation/multidrug efflux pump; aminoglycoside/multidrug efflux system 1475986 13692474 O3M_07145 Escherichia coli O104:H4 str. 2009EL-2050 aminoglycoside/multidrug efflux system YP_006769091.1 1472873 R 1134782 CDS YP_006769092.1 410481546 13692556 complement(1476150..1477850) 1 NC_018650.1 COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific; nitrate/nitrite sensor protein NarQ 1477850 13692556 O3M_07150 Escherichia coli O104:H4 str. 2009EL-2050 nitrate/nitrite sensor protein NarQ YP_006769092.1 1476150 R 1134782 CDS YP_006769093.1 410481547 13692557 1478056..1480035 1 NC_018650.1 COG1142 Fe-S-cluster-containing hydrogenase components 2; oxidoreductase Fe-S binding subunit 1480035 13692557 O3M_07155 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase Fe-S binding subunit YP_006769093.1 1478056 D 1134782 CDS YP_006769094.1 410481548 13692558 1480103..1480678 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; GDP-mannose pyrophosphatase NudK 1480678 13692558 O3M_07160 Escherichia coli O104:H4 str. 2009EL-2050 GDP-mannose pyrophosphatase NudK YP_006769094.1 1480103 D 1134782 CDS YP_006769095.1 410481549 13692559 1480804..1481847 1 NC_018650.1 COG1088 dTDP-D-glucose 4,6-dehydratase; hypothetical protein 1481847 13692559 O3M_07165 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769095.1 1480804 D 1134782 CDS YP_006769096.1 410481550 13692560 complement(1481943..1483946) 1 NC_018650.1 COG0021 Transketolase; transketolase 1483946 13692560 O3M_07170 Escherichia coli O104:H4 str. 2009EL-2050 transketolase YP_006769096.1 1481943 R 1134782 CDS YP_006769097.1 410481551 13692561 complement(1483966..1484916) 1 NC_018650.1 COG0176 Transaldolase; transaldolase A 1484916 13692561 O3M_07175 Escherichia coli O104:H4 str. 2009EL-2050 transaldolase A YP_006769097.1 1483966 R 1134782 CDS YP_006769098.1 410481552 13692562 1485205..1487484 1 NC_018650.1 COG0281 Malic enzyme; bifunctional malic enzyme oxidoreductase/phosphotransacetylase 1487484 13692562 O3M_07180 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional malic enzyme oxidoreductase/phosphotransacetylase YP_006769098.1 1485205 D 1134782 CDS YP_006769099.1 410481553 13692563 1487777..1488112 1 NC_018650.1 COG4810 Ethanolamine utilization protein; carboxysome structural protein EutS 1488112 13692563 O3M_07185 Escherichia coli O104:H4 str. 2009EL-2050 carboxysome structural protein EutS YP_006769099.1 1487777 D 1134782 CDS YP_006769100.1 410481554 13692564 1488125..1488604 1 NC_018650.1 COG4917 Ethanolamine utilization protein; ethanolamine utilization protein EutP 1488604 13692564 O3M_07190 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine utilization protein EutP YP_006769100.1 1488125 D 1134782 CDS YP_006769101.1 410481555 13692565 1488579..1489280 1 NC_018650.1 COG4766 Ethanolamine utilization protein; ethanolamine utilization protein EutQ 1489280 13692565 O3M_07195 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine utilization protein EutQ YP_006769101.1 1488579 D 1134782 CDS YP_006769102.1 410481556 13692566 1489277..1490080 1 NC_018650.1 COG4812 Ethanolamine utilization cobalamin adenosyltransferase; ethanolamine utilization cobalamin adenosyltransferase 1490080 13692566 O3M_07200 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine utilization cobalamin adenosyltransferase YP_006769102.1 1489277 D 1134782 CDS YP_006769103.1 410481557 13692567 1490077..1491093 1 NC_018650.1 COG0280 Phosphotransacetylase; phosphotransacetylase 1491093 eutD 13692567 eutD Escherichia coli O104:H4 str. 2009EL-2050 phosphotransacetylase YP_006769103.1 1490077 D 1134782 CDS YP_006769104.1 410481558 13692568 1491132..1491425 1 NC_018650.1 COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; carboxysome structural protein EutM 1491425 13692568 O3M_07210 Escherichia coli O104:H4 str. 2009EL-2050 carboxysome structural protein EutM YP_006769104.1 1491132 D 1134782 CDS YP_006769105.1 410481559 13692569 1491532..1491819 1 NC_018650.1 COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein; ethanolamine catabolic microcompartment shell protein EutN 1491819 13692569 O3M_07215 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine catabolic microcompartment shell protein EutN YP_006769105.1 1491532 D 1134782 CDS YP_006769106.1 410481560 13692570 1491831..1493234 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase EutE 1493234 13692570 O3M_07220 Escherichia coli O104:H4 str. 2009EL-2050 aldehyde dehydrogenase EutE YP_006769106.1 1491831 D 1134782 CDS YP_006769107.1 410481561 13692571 1493245..1494081 1 NC_018650.1 COG4820 Ethanolamine utilization protein, possible chaperonin; ethanolamine utilization protein EutJ 1494081 13692571 O3M_07225 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine utilization protein EutJ YP_006769107.1 1493245 D 1134782 CDS YP_006769108.1 410481562 13692572 1494071..1495258 1 NC_018650.1 COG1454 Alcohol dehydrogenase, class IV; ethanol dehydrogenase EutG 1495258 13692572 O3M_07230 Escherichia coli O104:H4 str. 2009EL-2050 ethanol dehydrogenase EutG YP_006769108.1 1494071 D 1134782 CDS YP_006769109.1 410481563 13692573 1495371..1495487 1 NC_018650.1 hypothetical protein 1495487 13692573 O3M_07235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769109.1 1495371 D 1134782 CDS YP_006769110.1 410481564 13692574 1495575..1496801 1 NC_018650.1 COG3192 Ethanolamine utilization protein; ethanolamine utilization protein EutH 1496801 13692574 O3M_07240 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine utilization protein EutH YP_006769110.1 1495575 D 1134782 CDS YP_006769111.1 410481565 13692575 1496798..1498201 1 NC_018650.1 COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition; reactivating factor for ethanolamine ammonia lyase 1498201 eutA 13692575 eutA Escherichia coli O104:H4 str. 2009EL-2050 reactivating factor for ethanolamine ammonia lyase YP_006769111.1 1496798 D 1134782 CDS YP_006769112.1 410481566 13692576 1498213..1499574 1 NC_018650.1 COG4303 Ethanolamine ammonia-lyase, large subunit; ethanolamine ammonia lyase large subunit 1499574 13692576 O3M_07250 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine ammonia lyase large subunit YP_006769112.1 1498213 D 1134782 CDS YP_006769113.1 410481567 13692577 1499595..1500482 1 NC_018650.1 COG4302 Ethanolamine ammonia-lyase, small subunit; ethanolamine ammonia-lyase small subunit 1500482 13692577 O3M_07255 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine ammonia-lyase small subunit YP_006769113.1 1499595 D 1134782 CDS YP_006769114.1 410481568 13692578 1500492..1501151 1 NC_018650.1 COG4816 Ethanolamine utilization protein; ethanolamine utilization protein EutL 1501151 13692578 O3M_07260 Escherichia coli O104:H4 str. 2009EL-2050 ethanolamine utilization protein EutL YP_006769114.1 1500492 D 1134782 CDS YP_006769115.1 410481569 13692579 1501164..1501664 1 NC_018650.1 COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; carboxysome structural protein EutK 1501664 13692579 O3M_07265 Escherichia coli O104:H4 str. 2009EL-2050 carboxysome structural protein EutK YP_006769115.1 1501164 D 1134782 CDS YP_006769116.1 410481570 13692580 1501710..1502762 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator EutR 1502762 13692580 O3M_07270 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator EutR YP_006769116.1 1501710 D 1134782 CDS YP_006769117.1 410481571 13692581 complement(1502768..1503667) 1 NC_018650.1 COG0408 Coproporphyrinogen III oxidase; coproporphyrinogen III oxidase 1503667 13692581 O3M_07275 Escherichia coli O104:H4 str. 2009EL-2050 coproporphyrinogen III oxidase YP_006769117.1 1502768 R 1134782 CDS YP_006769118.1 410481572 13692582 complement(1503671..1504540) 1 NC_018650.1 COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-l-alanine amidase I 1504540 13692582 O3M_07280 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmuramoyl-l-alanine amidase I YP_006769118.1 1503671 R 1134782 CDS YP_006769119.1 410481573 13692583 1504754..1505179 1 NC_018650.1 COG0456 Acetyltransferases; acetyltransferase 1505179 13692583 O3M_07285 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006769119.1 1504754 D 1134782 CDS YP_006769120.1 410481574 13692584 1505166..1505615 1 NC_018650.1 inner membrane protein 1505615 13692584 O3M_07290 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769120.1 1505166 D 1134782 CDS YP_006769121.1 410481575 13692585 1505676..1506251 1 NC_018650.1 RpoE-regulated lipoprotein 1506251 13692585 O3M_07295 Escherichia coli O104:H4 str. 2009EL-2050 RpoE-regulated lipoprotein YP_006769121.1 1505676 D 1134782 CDS YP_006769122.1 410481576 13692586 1506347..1507246 1 NC_018650.1 COG2837 Predicted iron-dependent peroxidase; dyp-type peroxidase family protein 1507246 13692586 O3M_07300 Escherichia coli O104:H4 str. 2009EL-2050 dyp-type peroxidase family protein YP_006769122.1 1506347 D 1134782 CDS YP_006769123.1 410481577 13692587 complement(1507302..1508606) 1 NC_018650.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; periplasmic esterase 1508606 13692587 O3M_07305 Escherichia coli O104:H4 str. 2009EL-2050 periplasmic esterase YP_006769123.1 1507302 R 1134782 CDS YP_006769124.1 410481578 13692588 complement(1508611..1510035) 1 NC_018650.1 COG1264 Phosphotransferase system IIB components; PTS system N-acetylmuramic acid transporter subunit IIBC 1510035 murP 13692588 murP Escherichia coli O104:H4 str. 2009EL-2050 PTS system N-acetylmuramic acid transporter subunit IIBC YP_006769124.1 1508611 R 1134782 CDS YP_006769125.1 410481579 13692589 complement(1510039..1510935) 1 NC_018650.1 COG2103 Predicted sugar phosphate isomerase; N-acetylmuramic acid 6-phosphate etherase 1510935 murQ 13692589 murQ Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmuramic acid 6-phosphate etherase YP_006769125.1 1510039 R 1134782 CDS YP_006769126.1 410481580 13692590 1511099..1511956 1 NC_018650.1 COG1737 Transcriptional regulators; transcriptional regulator MurR 1511956 13692590 O3M_07320 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator MurR YP_006769126.1 1511099 D 1134782 CDS YP_006769127.1 410481581 13692591 1512085..1512876 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 1512876 13692591 O3M_07325 Escherichia coli O104:H4 str. 2009EL-2050 short chain dehydrogenase YP_006769127.1 1512085 D 1134782 CDS YP_006769128.1 410481582 13692592 1513047..1514063 1 NC_018650.1 COG4150 ABC-type sulfate transport system, periplasmic component; thiosulfate transporter subunit 1514063 13692592 O3M_07330 Escherichia coli O104:H4 str. 2009EL-2050 thiosulfate transporter subunit YP_006769128.1 1513047 D 1134782 CDS YP_006769129.1 410481583 13692593 1514063..1514896 1 NC_018650.1 COG0555 ABC-type sulfate transport system, permease component; sulfate/thiosulfate transporter subunit 1514896 13692593 O3M_07335 Escherichia coli O104:H4 str. 2009EL-2050 sulfate/thiosulfate transporter subunit YP_006769129.1 1514063 D 1134782 CDS YP_006769130.1 410481584 13692594 1514896..1515771 1 NC_018650.1 COG4208 ABC-type sulfate transport system, permease component; sulfate/thiosulfate transporter permease subunit 1515771 cysW 13692594 cysW Escherichia coli O104:H4 str. 2009EL-2050 sulfate/thiosulfate transporter permease subunit YP_006769130.1 1514896 D 1134782 CDS YP_006769131.1 410481585 13692595 1515761..1516858 1 NC_018650.1 COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; sulfate/thiosulfate transporter subunit 1516858 13692595 O3M_07345 Escherichia coli O104:H4 str. 2009EL-2050 sulfate/thiosulfate transporter subunit YP_006769131.1 1515761 D 1134782 CDS YP_006769132.1 410481586 13692596 1516992..1517903 1 NC_018650.1 COG0031 Cysteine synthase; cysteine synthase B 1517903 cysM 13692596 cysM Escherichia coli O104:H4 str. 2009EL-2050 cysteine synthase B YP_006769132.1 1516992 D 1134782 CDS YP_006769133.1 410481587 13692597 complement(1517906..1518274) 1 NC_018650.1 hypothetical protein 1518274 13692597 O3M_07355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769133.1 1517906 R 1134782 CDS YP_006769134.1 410481588 13692598 1518379..1519230 1 NC_018650.1 COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase 1519230 pdxK 13692598 pdxK Escherichia coli O104:H4 str. 2009EL-2050 pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase YP_006769134.1 1518379 D 1134782 CDS YP_006769135.1 410481589 13692599 complement(1519272..1519781) 1 NC_018650.1 COG2190 Phosphotransferase system IIA components; PTS system glucose-specific transporter 1519781 13692599 O3M_07365 Escherichia coli O104:H4 str. 2009EL-2050 PTS system glucose-specific transporter YP_006769135.1 1519272 R 1134782 CDS YP_006769136.1 410481590 13692600 complement(1519822..1521549) 1 NC_018650.1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); phosphoenolpyruvate-protein phosphotransferase 1521549 13692600 O3M_07370 Escherichia coli O104:H4 str. 2009EL-2050 phosphoenolpyruvate-protein phosphotransferase YP_006769136.1 1519822 R 1134782 CDS YP_006769137.1 410481591 13692601 complement(1521594..1521851) 1 NC_018650.1 COG1925 Phosphotransferase system, HPr-related proteins; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 1521851 13692601 O3M_07375 Escherichia coli O104:H4 str. 2009EL-2050 PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr YP_006769137.1 1521594 R 1134782 CDS YP_006769138.1 410481592 13692602 complement(1522235..1523206) 1 NC_018650.1 COG0031 Cysteine synthase; cysteine synthase A 1523206 13692602 O3M_07380 Escherichia coli O104:H4 str. 2009EL-2050 cysteine synthase A YP_006769138.1 1522235 R 1134782 CDS YP_006769139.1 410481593 13692603 complement(1523391..1524152) 1 NC_018650.1 COG2981 Uncharacterized protein involved in cysteine biosynthesis; sulfate transport protein CysZ 1524152 13692603 O3M_07385 Escherichia coli O104:H4 str. 2009EL-2050 sulfate transport protein CysZ YP_006769139.1 1523391 R 1134782 CDS YP_006769140.1 410481594 13692604 1524382..1525368 1 NC_018650.1 COG3115 Cell division protein; cell division protein ZipA 1525368 13692604 O3M_07390 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein ZipA YP_006769140.1 1524382 D 1134782 CDS YP_006769141.1 410481595 13692605 1525439..1527454 1 NC_018650.1 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase LigA 1527454 ligA 13692605 ligA Escherichia coli O104:H4 str. 2009EL-2050 NAD-dependent DNA ligase LigA YP_006769141.1 1525439 D 1134782 CDS YP_006769142.1 410481596 13692606 1527456..1527674 1 NC_018650.1 COG3530 Uncharacterized protein conserved in bacteria; hypothetical protein 1527674 13692606 O3M_07400 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769142.1 1527456 D 1134782 CDS YP_006769143.1 410481597 13692607 complement(1527671..1528669) 1 NC_018650.1 COG0385 Predicted Na+-dependent transporter; hypothetical protein 1528669 13692607 O3M_07405 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769143.1 1527671 R 1134782 CDS YP_006769144.1 410481598 13692608 1528759..1529685 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 1529685 13692608 O3M_07410 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006769144.1 1528759 D 1134782 CDS YP_006769145.1 410481599 13692609 complement(1529724..1530488) 1 NC_018650.1 hypothetical protein 1530488 13692609 O3M_07415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769145.1 1529724 R 1134782 CDS YP_006769146.1 410481600 13692610 1530737..1531570 1 NC_018650.1 COG0005 Purine nucleoside phosphorylase; purine nucleoside phosphorylase 1531570 13692610 O3M_07420 Escherichia coli O104:H4 str. 2009EL-2050 purine nucleoside phosphorylase YP_006769146.1 1530737 D 1134782 CDS YP_006769147.1 410481601 13692611 1531630..1532886 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; xanthosine transporter 1532886 13692611 O3M_07425 Escherichia coli O104:H4 str. 2009EL-2050 xanthosine transporter YP_006769147.1 1531630 D 1134782 CDS YP_006769148.1 410481602 13692612 1532939..1533097 1 NC_018650.1 hypothetical protein 1533097 13692612 O3M_07430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769148.1 1532939 D 1134782 CDS YP_006769149.1 410481603 13692613 1533138..1534022 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional activator XapR 1534022 13692613 O3M_07435 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator XapR YP_006769149.1 1533138 D 1134782 CDS YP_006769150.1 410481604 13692618 1534943..1536358 1 NC_018650.1 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-tRNA synthetase 1536358 gltX 13692618 gltX Escherichia coli O104:H4 str. 2009EL-2050 glutamyl-tRNA synthetase YP_006769150.1 1534943 D 1134782 CDS YP_006769151.1 410481605 13692619 complement(1536410..1536802) 1 NC_018650.1 COG1396 Predicted transcriptional regulators; DNA-binding transcriptional regulator 1536802 13692619 O3M_07445 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006769151.1 1536410 R 1134782 CDS YP_006769152.1 410481606 13692620 complement(1536804..1537163) 1 NC_018650.1 hypothetical protein 1537163 13692620 O3M_07450 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769152.1 1536804 R 1134782 CDS YP_006769153.1 410481607 13692623 1537782..1539971 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 1539971 13692623 O3M_07455 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006769153.1 1537782 D 1134782 CDS YP_006769154.1 410481608 13692624 complement(1540021..1541223) 1 NC_018650.1 COG1972 Nucleoside permease; nucleoside (except guanosine) transporter NupC 1541223 13692624 O3M_07460 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside (except guanosine) transporter NupC YP_006769154.1 1540021 R 1134782 CDS YP_006769155.1 410481609 13692625 1541559..1542797 1 NC_018650.1 COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; manganese transport protein MntH 1542797 13692625 O3M_07465 Escherichia coli O104:H4 str. 2009EL-2050 manganese transport protein MntH YP_006769155.1 1541559 D 1134782 CDS YP_006769156.1 410481610 13692626 complement(1542938..1543264) 1 NC_018650.1 hypothetical protein 1543264 13692626 O3M_07470 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769156.1 1542938 R 1134782 CDS YP_006769157.1 410481611 13692627 complement(1543379..1544635) 1 NC_018650.1 COG1284 Uncharacterized conserved protein; ion channel protein 1544635 13692627 O3M_07475 Escherichia coli O104:H4 str. 2009EL-2050 ion channel protein YP_006769157.1 1543379 R 1134782 CDS YP_006769158.1 410481612 13692628 1544839..1545804 1 NC_018650.1 COG0837 Glucokinase; glucokinase 1545804 glk 13692628 glk Escherichia coli O104:H4 str. 2009EL-2050 glucokinase YP_006769158.1 1544839 D 1134782 CDS YP_006769159.1 410481613 13692629 1546023..1546349 1 NC_018650.1 COG1445 Phosphotransferase system fructose-specific component IIB; PTS system transporter subunit IIB 1546349 13692629 O3M_07485 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter subunit IIB YP_006769159.1 1546023 D 1134782 CDS YP_006769160.1 410481614 13692630 1546371..1547618 1 NC_018650.1 COG1299 Phosphotransferase system, fructose-specific IIC component; fructose-like permease IIC component 1547618 13692630 O3M_07490 Escherichia coli O104:H4 str. 2009EL-2050 fructose-like permease IIC component YP_006769160.1 1546371 D 1134782 CDS YP_006769161.1 410481615 13692631 1547633..1548718 1 NC_018650.1 COG0006 Xaa-Pro aminopeptidase; aminopeptidase 1548718 13692631 O3M_07495 Escherichia coli O104:H4 str. 2009EL-2050 aminopeptidase YP_006769161.1 1547633 D 1134782 CDS YP_006769162.1 410481616 13692632 1548718..1549755 1 NC_018650.1 COG1363 Cellulase M and related proteins; exoaminopeptidase 1549755 13692632 O3M_07500 Escherichia coli O104:H4 str. 2009EL-2050 exoaminopeptidase YP_006769162.1 1548718 D 1134782 CDS YP_006769163.1 410481617 13692633 1549780..1552275 1 NC_018650.1 Hpr component; enzyme I component; enzyme IIA component; COG1925 Phosphotransferase system, HPr-related proteins; PTS system transporter multiphosphoryl transfer protein 1552275 13692633 O3M_07505 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter multiphosphoryl transfer protein YP_006769163.1 1549780 D 1134782 CDS YP_006769164.1 410481618 13692634 complement(1552278..1553135) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding protein, ARAC-type 1553135 13692634 O3M_07510 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding protein, ARAC-type YP_006769164.1 1552278 R 1134782 CDS YP_006769165.1 410481619 13692635 complement(1553148..1553882) 1 NC_018650.1 COG3279 Response regulator of the LytR/AlgR family; hypothetical protein 1553882 13692635 O3M_07515 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769165.1 1553148 R 1134782 CDS YP_006769166.1 410481620 13692636 complement(1553897..1555594) 1 NC_018650.1 COG3275 Putative regulator of cell autolysis; hypothetical protein 1555594 13692636 O3M_07520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769166.1 1553897 R 1134782 CDS YP_006769167.1 410481621 13693054 1555971..1557209 1 NC_018650.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase 1557209 13693054 O3M_07525 Escherichia coli O104:H4 str. 2009EL-2050 aminotransferase YP_006769167.1 1555971 D 1134782 CDS YP_006769168.1 410481622 13693055 complement(1557701..1558621) 1 NC_018650.1 COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis palmitoleoyl acyltransferase 1558621 13693055 O3M_07530 Escherichia coli O104:H4 str. 2009EL-2050 lipid A biosynthesis palmitoleoyl acyltransferase YP_006769168.1 1557701 R 1134782 CDS YP_006769169.1 410481623 13693056 1558974..1559216 1 NC_018650.1 inner membrane protein 1559216 13693056 O3M_07535 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769169.1 1558974 D 1134782 CDS YP_006769170.1 410481624 13693057 complement(1559293..1559568) 1 NC_018650.1 lipoprotein 1559568 13693057 O3M_07540 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006769170.1 1559293 R 1134782 CDS YP_006769171.1 410481625 13693058 1559864..1560496 1 NC_018650.1 hypothetical protein 1560496 13693058 O3M_07545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769171.1 1559864 D 1134782 CDS YP_006769172.1 410481626 13693059 1561009..1562259 1 NC_018650.1 COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; formyl-coenzyme A transferase 1562259 13693059 O3M_07550 Escherichia coli O104:H4 str. 2009EL-2050 formyl-coenzyme A transferase YP_006769172.1 1561009 D 1134782 CDS YP_006769173.1 410481627 13693060 1562313..1564007 1 NC_018650.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; oxalyl-CoA decarboxylase 1564007 13693060 O3M_07555 Escherichia coli O104:H4 str. 2009EL-2050 oxalyl-CoA decarboxylase YP_006769173.1 1562313 D 1134782 CDS YP_006769174.1 410481628 13693061 1564077..1565021 1 NC_018650.1 COG0679 Predicted permeases; transporter YfdV 1565021 13693061 O3M_07560 Escherichia coli O104:H4 str. 2009EL-2050 transporter YfdV YP_006769174.1 1564077 D 1134782 CDS YP_006769175.1 410481629 13693062 1565095..1566240 1 NC_018650.1 COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; CoA-transferase 1566240 13693062 O3M_07565 Escherichia coli O104:H4 str. 2009EL-2050 CoA-transferase YP_006769175.1 1565095 D 1134782 CDS YP_006769176.1 410481630 13693063 complement(1566296..1569889) 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; hybrid sensory histidine kinase in two-component regulatory system with EvgA 1569889 13693063 O3M_07570 Escherichia coli O104:H4 str. 2009EL-2050 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_006769176.1 1566296 R 1134782 CDS YP_006769177.1 410481631 13693064 complement(1569894..1570508) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator EvgA 1570508 13693064 O3M_07575 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator EvgA YP_006769177.1 1569894 R 1134782 CDS YP_006769178.1 410481632 13693065 1570924..1572087 1 NC_018650.1 COG1566 Multidrug resistance efflux pump; EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component 1572087 13693065 O3M_07580 Escherichia coli O104:H4 str. 2009EL-2050 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component YP_006769178.1 1570924 D 1134782 CDS YP_006769179.1 410481633 13693066 1572087..1573625 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein Y 1573625 13693066 O3M_07585 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein Y YP_006769179.1 1572087 D 1134782 CDS YP_006769180.1 410481634 13693067 complement(1573733..1575061) 1 NC_018650.1 COG3048 D-serine dehydratase; D-serine dehydratase 1575061 13693067 O3M_07590 Escherichia coli O104:H4 str. 2009EL-2050 D-serine dehydratase YP_006769180.1 1573733 R 1134782 CDS YP_006769181.1 410481635 13693068 complement(1575079..1575297) 1 NC_018650.1 COG2610 H+/gluconate symporter and related permeases; permease DsdX 1575297 13693068 O3M_07595 Escherichia coli O104:H4 str. 2009EL-2050 permease DsdX YP_006769181.1 1575079 R 1134782 CDS YP_006769182.1 410481636 13693069 1575528..1576523 1 NC_018650.1 COG1609 Transcriptional regulators; sucrose operon repressor 1576523 13693069 O3M_07600 Escherichia coli O104:H4 str. 2009EL-2050 sucrose operon repressor YP_006769182.1 1575528 D 1134782 CDS YP_006769183.1 410481637 13693070 complement(1576531..1577964) 1 NC_018650.1 COG1621 Beta-fructosidases (levanase/invertase); sucrose-6-phosphate hydrolase 1577964 13693070 O3M_07605 Escherichia coli O104:H4 str. 2009EL-2050 sucrose-6-phosphate hydrolase YP_006769183.1 1576531 R 1134782 CDS YP_006769184.1 410481638 13693071 1578180..1579094 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; aminoimidazole riboside kinase 1579094 13693071 O3M_07610 Escherichia coli O104:H4 str. 2009EL-2050 aminoimidazole riboside kinase YP_006769184.1 1578180 D 1134782 CDS YP_006769185.1 410481639 13693072 1579166..1580413 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; galactoside permease 1580413 lacY 13693072 lacY Escherichia coli O104:H4 str. 2009EL-2050 galactoside permease YP_006769185.1 1579166 D 1134782 CDS YP_006769186.1 410481640 13693073 complement(1580943..1581143) 1 NC_018650.1 hypothetical protein 1581143 13693073 O3M_07620 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769186.1 1580943 R 1134782 CDS YP_006769187.1 410481641 13693074 complement(1581275..1581454) 1 NC_018650.1 hypothetical protein 1581454 13693074 O3M_07625 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769187.1 1581275 R 1134782 CDS YP_006769188.1 410481642 13693075 complement(1582177..1582386) 1 NC_018650.1 prophage protein 1582386 13693075 O3M_07635 Escherichia coli O104:H4 str. 2009EL-2050 prophage protein YP_006769188.1 1582177 R 1134782 CDS YP_006769189.1 410481643 13693076 complement(1582749..1583420) 1 NC_018650.1 COG0529 Adenylylsulfate kinase and related kinases; hypothetical protein 1583420 13693076 O3M_07640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769189.1 1582749 R 1134782 CDS YP_006769190.1 410481644 13693077 complement(1583417..1583584) 1 NC_018650.1 hypothetical protein 1583584 13693077 O3M_07645 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769190.1 1583417 R 1134782 CDS YP_006769191.1 410481645 13693078 complement(1583581..1583871) 1 NC_018650.1 hypothetical protein 1583871 13693078 O3M_07650 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769191.1 1583581 R 1134782 CDS YP_006769192.1 410481646 13693079 complement(1583882..1584178) 1 NC_018650.1 Anti-RecBCD protein 2 1584178 13693079 O3M_07655 Escherichia coli O104:H4 str. 2009EL-2050 Anti-RecBCD protein 2 YP_006769192.1 1583882 R 1134782 CDS YP_006769193.1 410481647 13693080 complement(1584202..1584585) 1 NC_018650.1 hypothetical protein 1584585 13693080 O3M_07660 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769193.1 1584202 R 1134782 CDS YP_006769194.1 410481648 13693081 complement(1584585..1585190) 1 NC_018650.1 essential recombination function protein Erf; DNA single-strand annealing protein 1585190 13693081 O3M_07665 Escherichia coli O104:H4 str. 2009EL-2050 DNA single-strand annealing protein YP_006769194.1 1584585 R 1134782 CDS YP_006769195.1 410481649 13693082 complement(1585201..1585371) 1 NC_018650.1 hypothetical protein 1585371 13693082 O3M_07670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769195.1 1585201 R 1134782 CDS YP_006769196.1 410481650 13693083 complement(1585447..1585599) 1 NC_018650.1 host killing protein 1585599 13693083 O3M_07675 Escherichia coli O104:H4 str. 2009EL-2050 host killing protein YP_006769196.1 1585447 R 1134782 CDS YP_006769197.1 410481651 13693084 complement(1585584..1585715) 1 NC_018650.1 regulatory protein CIII 1585715 13693084 O3M_07680 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein CIII YP_006769197.1 1585584 R 1134782 CDS YP_006769198.1 410481652 13693085 1585945..1586220 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 1586220 13693085 O3M_07685 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006769198.1 1585945 D 1134782 CDS YP_006769199.1 410481653 13693086 1586139..1586642 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 1586642 13693086 O3M_07690 Escherichia coli O104:H4 str. 2009EL-2050 transposase InsB IS1 YP_006769199.1 1586139 D 1134782 CDS YP_006769200.1 410481654 13693087 1586660..1588372 1 NC_018650.1 hypothetical protein 1588372 13693087 O3M_07695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769200.1 1586660 D 1134782 CDS YP_006769201.1 410481655 13693088 complement(1588443..1590353) 1 NC_018650.1 COG1835 Predicted acyltransferases; hypothetical protein 1590353 13693088 O3M_07700 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769201.1 1588443 R 1134782 CDS YP_006769202.1 410481656 13693089 complement(1590582..1591739) 1 NC_018650.1 CPS-53 (KpLE1) prophage; COG0582 Integrase; prophage CPS-53 integrase 1591739 13693089 O3M_07705 Escherichia coli O104:H4 str. 2009EL-2050 prophage CPS-53 integrase YP_006769202.1 1590582 R 1134782 CDS YP_006769203.1 410481657 13693091 complement(1592051..1592983) 1 NC_018650.1 COG2116 Formate/nitrite family of transporters; hypothetical protein 1592983 13693091 O3M_07710 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769203.1 1592051 R 1134782 CDS YP_006769204.1 410481658 13693092 1593277..1594032 1 NC_018650.1 COG2853 Surface lipoprotein; ABC transporter outer membrane lipoprotein 1594032 13693092 O3M_07715 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter outer membrane lipoprotein YP_006769204.1 1593277 D 1134782 CDS YP_006769205.1 410481659 13693093 complement(1594214..1595272) 1 NC_018650.1 hypothetical protein 1595272 13693093 O3M_07720 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769205.1 1594214 R 1134782 CDS YP_006769206.1 410481660 13693094 complement(1595638..1596978) 1 NC_018650.1 COG2067 Long-chain fatty acid transport protein; long-chain fatty acid outer membrane transporter 1596978 13693094 O3M_07725 Escherichia coli O104:H4 str. 2009EL-2050 long-chain fatty acid outer membrane transporter YP_006769206.1 1595638 R 1134782 CDS YP_006769207.1 410481661 13693095 1597350..1597634 1 NC_018650.1 COG3691 Uncharacterized protein conserved in bacteria; hypothetical protein 1597634 13693095 O3M_07730 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769207.1 1597350 D 1134782 CDS YP_006769208.1 410481662 13693096 1597814..1599124 1 NC_018650.1 COG0183 Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase 1599124 fadI 13693096 fadI Escherichia coli O104:H4 str. 2009EL-2050 3-ketoacyl-CoA thiolase YP_006769208.1 1597814 D 1134782 CDS YP_006769209.1 410481663 13693097 1599124..1601268 1 NC_018650.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; multifunctional fatty acid oxidation complex subunit alpha 1601268 fadJ 13693097 fadJ Escherichia coli O104:H4 str. 2009EL-2050 multifunctional fatty acid oxidation complex subunit alpha YP_006769209.1 1599124 D 1134782 CDS YP_006769210.1 410481664 13693098 1601471..1601956 1 NC_018650.1 COG2062 Phosphohistidine phosphatase SixA; phosphohistidine phosphatase 1601956 13693098 O3M_07745 Escherichia coli O104:H4 str. 2009EL-2050 phosphohistidine phosphatase YP_006769210.1 1601471 D 1134782 CDS YP_006769211.1 410481665 13693099 1602631..1603194 1 NC_018650.1 fimbrial-like protein 1603194 13693099 O3M_07750 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like protein YP_006769211.1 1602631 D 1134782 CDS YP_006769212.1 410481666 13693100 1603276..1605918 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein StfC 1605918 13693100 O3M_07755 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial outer membrane usher protein StfC YP_006769212.1 1603276 D 1134782 CDS YP_006769213.1 410481667 13693101 1605938..1606690 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; chaperone 1606690 13693101 O3M_07760 Escherichia coli O104:H4 str. 2009EL-2050 chaperone YP_006769213.1 1605938 D 1134782 CDS YP_006769214.1 410481668 13693102 1606707..1607213 1 NC_018650.1 minor fimbrial subunit 1607213 13693102 O3M_07765 Escherichia coli O104:H4 str. 2009EL-2050 minor fimbrial subunit YP_006769214.1 1606707 D 1134782 CDS YP_006769215.1 410481669 13693103 1607210..1607680 1 NC_018650.1 fimbrial subunit protein 1607680 13693103 O3M_07770 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial subunit protein YP_006769215.1 1607210 D 1134782 CDS YP_006769216.1 410481670 13693104 1607677..1608201 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial subunit protein 1608201 13693104 O3M_07775 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial subunit protein YP_006769216.1 1607677 D 1134782 CDS YP_006769217.1 410481671 13693105 1608293..1609060 1 NC_018650.1 hypothetical protein 1609060 13693105 O3M_07780 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769217.1 1608293 D 1134782 CDS YP_006769218.1 410481672 13693106 1609287..1610267 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 1610267 13693106 O3M_07785 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006769218.1 1609287 D 1134782 CDS YP_006769219.1 410481673 13693107 complement(1610461..1611012) 1 NC_018650.1 COG2840 Uncharacterized protein conserved in bacteria; hypothetical protein 1611012 13693107 O3M_07790 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769219.1 1610461 R 1134782 CDS YP_006769220.1 410481674 13693108 1611178..1612110 1 NC_018650.1 COG2890 Methylase of polypeptide chain release factors; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1612110 13693108 O3M_07795 Escherichia coli O104:H4 str. 2009EL-2050 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_006769220.1 1611178 D 1134782 CDS YP_006769221.1 410481675 13693109 1612145..1613230 1 NC_018650.1 COG0082 Chorismate synthase; chorismate synthase 1613230 13693109 O3M_07800 Escherichia coli O104:H4 str. 2009EL-2050 chorismate synthase YP_006769221.1 1612145 D 1134782 CDS YP_006769222.1 410481676 13693110 1613234..1614058 1 NC_018650.1 COG3770 Murein endopeptidase; penicillin-insensitive murein endopeptidase 1614058 mepA 13693110 mepA Escherichia coli O104:H4 str. 2009EL-2050 penicillin-insensitive murein endopeptidase YP_006769222.1 1613234 D 1134782 CDS YP_006769223.1 410481677 13693111 1614058..1614867 1 NC_018650.1 COG0730 Predicted permeases; hypothetical protein 1614867 13693111 O3M_07810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769223.1 1614058 D 1134782 CDS YP_006769224.1 410481678 13693112 1614867..1615415 1 NC_018650.1 COG3101 Uncharacterized protein conserved in bacteria; hypothetical protein 1615415 13693112 O3M_07815 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769224.1 1614867 D 1134782 CDS YP_006769225.1 410481679 13693113 1615449..1615727 1 NC_018650.1 hypothetical protein 1615727 13693113 O3M_07820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769225.1 1615449 D 1134782 CDS YP_006769226.1 410481680 13693114 complement(1615848..1617854) 1 NC_018650.1 COG4121 Uncharacterized conserved protein; bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase 1617854 mnmC 13693114 mnmC Escherichia coli O104:H4 str. 2009EL-2050 bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase YP_006769226.1 1615848 R 1134782 CDS YP_006769227.1 410481681 13693115 1618013..1619233 1 NC_018650.1 COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-ACP synthase 1619233 13693115 O3M_07830 Escherichia coli O104:H4 str. 2009EL-2050 3-oxoacyl-ACP synthase YP_006769227.1 1618013 D 1134782 CDS YP_006769228.1 410481682 13693116 1619517..1620695 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 1620695 13693116 O3M_07835 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769228.1 1619517 D 1134782 CDS YP_006769229.1 410481683 13693117 complement(1620692..1621687) 1 NC_018650.1 flagella biosynthesis regulator 1621687 flk 13693117 flk Escherichia coli O104:H4 str. 2009EL-2050 flagella biosynthesis regulator YP_006769229.1 1620692 R 1134782 CDS YP_006769230.1 410481684 13693118 1621786..1622922 1 NC_018650.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; erythronate-4-phosphate dehydrogenase PdxB 1622922 13693118 O3M_07845 Escherichia coli O104:H4 str. 2009EL-2050 erythronate-4-phosphate dehydrogenase PdxB YP_006769230.1 1621786 D 1134782 CDS YP_006769231.1 410481685 13693119 1622988..1624001 1 NC_018650.1 COG0136 Aspartate-semialdehyde dehydrogenase; semialdehyde dehydrogenase 1624001 13693119 O3M_07850 Escherichia coli O104:H4 str. 2009EL-2050 semialdehyde dehydrogenase YP_006769231.1 1622988 D 1134782 CDS YP_006769232.1 410481686 13693120 1624001..1624813 1 NC_018650.1 COG0101 Pseudouridylate synthase; tRNA pseudouridine synthase A 1624813 truA 13693120 truA Escherichia coli O104:H4 str. 2009EL-2050 tRNA pseudouridine synthase A YP_006769232.1 1624001 D 1134782 CDS YP_006769233.1 410481687 13693121 1624896..1625555 1 NC_018650.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 1625555 13693121 O3M_07860 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769233.1 1624896 D 1134782 CDS YP_006769234.1 410481688 13693122 1625711..1626625 1 NC_018650.1 COG0777 Acetyl-CoA carboxylase beta subunit; acetyl-CoA carboxylase subunit beta 1626625 13693122 O3M_07865 Escherichia coli O104:H4 str. 2009EL-2050 acetyl-CoA carboxylase subunit beta YP_006769234.1 1625711 D 1134782 CDS YP_006769235.1 410481689 13693123 1626695..1627963 1 NC_018650.1 COG0285 Folylpolyglutamate synthase; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 1627963 13693123 O3M_07870 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional folylpolyglutamate synthase/dihydrofolate synthase YP_006769235.1 1626695 D 1134782 CDS YP_006769236.1 410481690 13693124 1627953..1628615 1 NC_018650.1 COG3147 Uncharacterized protein conserved in bacteria; cell division protein DedD 1628615 13693124 O3M_07875 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein DedD YP_006769236.1 1627953 D 1134782 CDS YP_006769237.1 410481691 13693125 1628874..1629362 1 NC_018650.1 COG1286 Uncharacterized membrane protein, required for colicin V production; colicin V production protein 1629362 13693125 O3M_07880 Escherichia coli O104:H4 str. 2009EL-2050 colicin V production protein YP_006769237.1 1628874 D 1134782 CDS YP_006769238.1 410481692 13693126 1629399..1630916 1 NC_018650.1 COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; amidophosphoribosyltransferase 1630916 13693126 O3M_07885 Escherichia coli O104:H4 str. 2009EL-2050 amidophosphoribosyltransferase YP_006769238.1 1629399 D 1134782 CDS YP_006769239.1 410481693 13693127 1631011..1631580 1 NC_018650.1 COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1631580 13693127 O3M_07890 Escherichia coli O104:H4 str. 2009EL-2050 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_006769239.1 1631011 D 1134782 CDS YP_006769240.1 410481694 13693128 1631846..1632628 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; lysine/arginine/ornithine ABC transporter substrate-binding protein 1632628 13693128 O3M_07895 Escherichia coli O104:H4 str. 2009EL-2050 lysine/arginine/ornithine ABC transporter substrate-binding protein YP_006769240.1 1631846 D 1134782 CDS YP_006769241.1 410481695 13693129 1632849..1633631 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; histidine ABC transporter substrate-binding protein HisJ 1633631 13693129 O3M_07900 Escherichia coli O104:H4 str. 2009EL-2050 histidine ABC transporter substrate-binding protein HisJ YP_006769241.1 1632849 D 1134782 CDS YP_006769242.1 410481696 13693130 1633721..1634407 1 NC_018650.1 COG4215 ABC-type arginine transport system, permease component; histidine/lysine/arginine/ornithine ABC transporter permease HisQ 1634407 13693130 O3M_07905 Escherichia coli O104:H4 str. 2009EL-2050 histidine/lysine/arginine/ornithine ABC transporter permease HisQ YP_006769242.1 1633721 D 1134782 CDS YP_006769243.1 410481697 13693131 1634404..1635120 1 NC_018650.1 COG4160 ABC-type arginine/histidine transport system, permease component; histidine/lysine/arginine/ornithine ABC transporter permease HisM 1635120 13693131 O3M_07910 Escherichia coli O104:H4 str. 2009EL-2050 histidine/lysine/arginine/ornithine ABC transporter permease HisM YP_006769243.1 1634404 D 1134782 CDS YP_006769244.1 410481698 13693132 1635128..1635901 1 NC_018650.1 COG4598 ABC-type histidine transport system, ATPase component; histidine/lysine/arginine/ornithine transporter subunit 1635901 13693132 O3M_07915 Escherichia coli O104:H4 str. 2009EL-2050 histidine/lysine/arginine/ornithine transporter subunit YP_006769244.1 1635128 D 1134782 CDS YP_006769245.1 410481699 13693133 1636098..1637000 1 NC_018650.1 transposase 1637000 13693133 O3M_07920 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006769245.1 1636098 D 1134782 CDS YP_006769246.1 410481700 13693134 complement(1637048..1637941) 1 NC_018650.1 NAD(P)-binding Rossmann-fold domain; COG1090 Predicted nucleoside-diphosphate sugar epimerase; NAD dependent epimerase/dehydratase family protein 1637941 13693134 O3M_07925 Escherichia coli O104:H4 str. 2009EL-2050 NAD dependent epimerase/dehydratase family protein YP_006769246.1 1637048 R 1134782 CDS YP_006769247.1 410481701 13693135 complement(1637962..1638324) 1 NC_018650.1 COG1539 Dihydroneopterin aldolase; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 1638324 folX 13693135 folX Escherichia coli O104:H4 str. 2009EL-2050 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_006769247.1 1637962 R 1134782 CDS YP_006769248.1 410481702 13693136 complement(1638381..1639028) 1 NC_018650.1 COG0625 Glutathione S-transferase; GSH-dependent disulfide bond oxidoreductase 1639028 13693136 O3M_07935 Escherichia coli O104:H4 str. 2009EL-2050 GSH-dependent disulfide bond oxidoreductase YP_006769248.1 1638381 R 1134782 CDS YP_006769249.1 410481703 13693137 1639164..1639808 1 NC_018650.1 COG0625 Glutathione S-transferase; glutathione S-transferase 1639808 13693137 O3M_07940 Escherichia coli O104:H4 str. 2009EL-2050 glutathione S-transferase YP_006769249.1 1639164 D 1134782 CDS YP_006769250.1 410481704 13693138 1639864..1640415 1 NC_018650.1 COG0622 Predicted phosphoesterase; phosphodiesterase 1640415 13693138 O3M_07945 Escherichia coli O104:H4 str. 2009EL-2050 phosphodiesterase YP_006769250.1 1639864 D 1134782 CDS YP_006769251.1 410481705 13693139 1640473..1641015 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase YfcD 1641015 13693139 O3M_07950 Escherichia coli O104:H4 str. 2009EL-2050 NUDIX hydrolase YfcD YP_006769251.1 1640473 D 1134782 CDS YP_006769252.1 410481706 13693140 complement(1641048..1642568) 1 NC_018650.1 COG1288 Predicted membrane protein; hypothetical protein 1642568 13693140 O3M_07955 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769252.1 1641048 R 1134782 CDS YP_006769253.1 410481707 13693141 complement(1642758..1644902) 1 NC_018650.1 COG0857 BioD-like N-terminal domain of phosphotransacetylase; phosphate acetyltransferase 1644902 13693141 O3M_07960 Escherichia coli O104:H4 str. 2009EL-2050 phosphate acetyltransferase YP_006769253.1 1642758 R 1134782 CDS YP_006769254.1 410481708 13693142 complement(1644977..1646179) 1 NC_018650.1 COG0282 Acetate kinase; acetate kinase A/propionate kinase 2 1646179 13693142 O3M_07965 Escherichia coli O104:H4 str. 2009EL-2050 acetate kinase A/propionate kinase 2 YP_006769254.1 1644977 R 1134782 CDS YP_006769255.1 410481709 13693143 1646317..1646448 1 NC_018650.1 hypothetical protein 1646448 13693143 O3M_07970 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769255.1 1646317 D 1134782 CDS YP_006769256.1 410481710 13693144 1646517..1646972 1 NC_018650.1 COG3092 Uncharacterized protein conserved in bacteria; hypothetical protein 1646972 13693144 O3M_07975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769256.1 1646517 D 1134782 CDS YP_006769257.1 410481711 13693145 1647055..1647549 1 NC_018650.1 COG3013 Uncharacterized conserved protein; hypothetical protein 1647549 13693145 O3M_07980 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769257.1 1647055 D 1134782 CDS YP_006769258.1 410481712 13693146 1647560..1648210 1 NC_018650.1 COG0637 Predicted phosphatase/phosphohexomutase; phosphatase 1648210 13693146 O3M_07985 Escherichia coli O104:H4 str. 2009EL-2050 phosphatase YP_006769258.1 1647560 D 1134782 CDS YP_006769259.1 410481713 13693147 1648297..1650129 1 NC_018650.1 COG0471 Di- and tricarboxylate transporters; transporter 1650129 13693147 O3M_07990 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769259.1 1648297 D 1134782 CDS YP_006769260.1 410481714 13693148 complement(1650188..1650787) 1 NC_018650.1 COG1896 Predicted hydrolases of HD superfamily; 5'-nucleotidase 1650787 13693148 O3M_07995 Escherichia coli O104:H4 str. 2009EL-2050 5'-nucleotidase YP_006769260.1 1650188 R 1134782 CDS YP_006769261.1 410481715 13693149 complement(1650871..1652088) 1 NC_018650.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase AlaT 1652088 13693149 O3M_08000 Escherichia coli O104:H4 str. 2009EL-2050 aminotransferase AlaT YP_006769261.1 1650871 R 1134782 CDS YP_006769262.1 410481716 13693150 1653008..1653946 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional repressor LrhA 1653946 13693150 O3M_08005 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor LrhA YP_006769262.1 1653008 D 1134782 CDS YP_006769263.1 410481717 13693151 1654577..1655020 1 NC_018650.1 COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); NADH:ubiquinone oxidoreductase subunit A 1655020 13693151 O3M_08010 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit A YP_006769263.1 1654577 D 1134782 CDS YP_006769264.1 410481718 13693152 1655036..1655698 1 NC_018650.1 COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; NADH dehydrogenase subunit B 1655698 13693152 O3M_08015 Escherichia coli O104:H4 str. 2009EL-2050 NADH dehydrogenase subunit B YP_006769264.1 1655036 D 1134782 CDS YP_006769265.1 410481719 13693153 1655792..1657594 1 NC_018650.1 COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; NADH:ubiquinone oxidoreductase subunit C/D 1657594 13693153 O3M_08020 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit C/D YP_006769265.1 1655792 D 1134782 CDS YP_006769266.1 410481720 13693154 1657597..1658097 1 NC_018650.1 COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; NADH dehydrogenase subunit E 1658097 13693154 O3M_08025 Escherichia coli O104:H4 str. 2009EL-2050 NADH dehydrogenase subunit E YP_006769266.1 1657597 D 1134782 CDS YP_006769267.1 410481721 13693155 1658094..1659431 1 NC_018650.1 COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; NADH dehydrogenase I subunit F 1659431 13693155 O3M_08030 Escherichia coli O104:H4 str. 2009EL-2050 NADH dehydrogenase I subunit F YP_006769267.1 1658094 D 1134782 CDS YP_006769268.1 410481722 13693156 1659484..1662210 1 NC_018650.1 COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); NADH dehydrogenase subunit G 1662210 13693156 O3M_08035 Escherichia coli O104:H4 str. 2009EL-2050 NADH dehydrogenase subunit G YP_006769268.1 1659484 D 1134782 CDS YP_006769269.1 410481723 13693157 1662207..1663184 1 NC_018650.1 COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); NADH:ubiquinone oxidoreductase subunit H 1663184 13693157 O3M_08040 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit H YP_006769269.1 1662207 D 1134782 CDS YP_006769270.1 410481724 13693158 1663199..1663741 1 NC_018650.1 COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); NADH dehydrogenase subunit I 1663741 13693158 O3M_08045 Escherichia coli O104:H4 str. 2009EL-2050 NADH dehydrogenase subunit I YP_006769270.1 1663199 D 1134782 CDS YP_006769271.1 410481725 13693159 1663753..1664307 1 NC_018650.1 COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); NADH:ubiquinone oxidoreductase subunit J 1664307 13693159 O3M_08050 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit J YP_006769271.1 1663753 D 1134782 CDS YP_006769272.1 410481726 13693160 1664304..1664606 1 NC_018650.1 COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); NADH:ubiquinone oxidoreductase subunit K 1664606 13693160 O3M_08055 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit K YP_006769272.1 1664304 D 1134782 CDS YP_006769273.1 410481727 13693161 1664603..1666444 1 NC_018650.1 COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; NADH:ubiquinone oxidoreductase subunit L 1666444 13693161 O3M_08060 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit L YP_006769273.1 1664603 D 1134782 CDS YP_006769274.1 410481728 13693162 1666608..1668137 1 NC_018650.1 COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); NADH:ubiquinone oxidoreductase subunit M 1668137 13693162 O3M_08065 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit M YP_006769274.1 1666608 D 1134782 CDS YP_006769275.1 410481729 13693163 1668144..1669601 1 NC_018650.1 COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); NADH:ubiquinone oxidoreductase subunit N 1669601 13693163 O3M_08070 Escherichia coli O104:H4 str. 2009EL-2050 NADH:ubiquinone oxidoreductase subunit N YP_006769275.1 1668144 D 1134782 CDS YP_006769276.1 410481730 13693164 complement(1669668..1670171) 1 NC_018650.1 hypothetical protein 1670171 13693164 O3M_08075 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769276.1 1669668 R 1134782 CDS YP_006769277.1 410481731 13693165 complement(1670297..1670476) 1 NC_018650.1 COG2234 Predicted aminopeptidases; Zn-dependent exopeptidase 1670476 13693165 O3M_08080 Escherichia coli O104:H4 str. 2009EL-2050 Zn-dependent exopeptidase YP_006769277.1 1670297 R 1134782 CDS YP_006769278.1 410481732 13693166 complement(1672701..1673618) 1 NC_018650.1 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; ribonuclease Z 1673618 13693166 O3M_08095 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease Z YP_006769278.1 1672701 R 1134782 CDS YP_006769279.1 410481733 13693167 1673683..1674144 1 NC_018650.1 COG2153 Predicted acyltransferase; acyltransferase 1674144 13693167 O3M_08100 Escherichia coli O104:H4 str. 2009EL-2050 acyltransferase YP_006769279.1 1673683 D 1134782 CDS YP_006769280.1 410481734 13693168 1674199..1674504 1 NC_018650.1 COG4575 Uncharacterized conserved protein; hypothetical protein 1674504 13693168 O3M_08105 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769280.1 1674199 D 1134782 CDS YP_006769281.1 410481735 13693169 1674583..1675878 1 NC_018650.1 COG1169 Isochorismate synthase; menaquinone-specific isochorismate synthase 1675878 13693169 O3M_08110 Escherichia coli O104:H4 str. 2009EL-2050 menaquinone-specific isochorismate synthase YP_006769281.1 1674583 D 1134782 CDS YP_006769282.1 410481736 13693170 1675967..1677637 1 NC_018650.1 COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1677637 13693170 O3M_08115 Escherichia coli O104:H4 str. 2009EL-2050 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_006769282.1 1675967 D 1134782 CDS YP_006769283.1 410481737 13693171 1677634..1678392 1 NC_018650.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase 1678392 13693171 O3M_08120 Escherichia coli O104:H4 str. 2009EL-2050 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase YP_006769283.1 1677634 D 1134782 CDS YP_006769284.1 410481738 13693172 1678407..1679264 1 NC_018650.1 COG0447 Dihydroxynaphthoic acid synthase; dihydroxynaphthoic acid synthetase 1679264 13693172 O3M_08125 Escherichia coli O104:H4 str. 2009EL-2050 dihydroxynaphthoic acid synthetase YP_006769284.1 1678407 D 1134782 CDS YP_006769285.1 410481739 13693173 1679264..1680226 1 NC_018650.1 COG1441 O-succinylbenzoate synthase; O-succinylbenzoate synthase 1680226 13693173 O3M_08130 Escherichia coli O104:H4 str. 2009EL-2050 O-succinylbenzoate synthase YP_006769285.1 1679264 D 1134782 CDS YP_006769286.1 410481740 13693174 1680223..1681578 1 NC_018650.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; O-succinylbenzoic acid--CoA ligase 1681578 13693174 O3M_08135 Escherichia coli O104:H4 str. 2009EL-2050 O-succinylbenzoic acid--CoA ligase YP_006769286.1 1680223 D 1134782 CDS YP_006769287.1 410481741 13693175 1681688..1681954 1 NC_018650.1 COG1601 Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain; signal transduction protein PmrD 1681954 13693175 O3M_08140 Escherichia coli O104:H4 str. 2009EL-2050 signal transduction protein PmrD YP_006769287.1 1681688 D 1134782 CDS YP_006769288.1 410481742 13693176 complement(1681948..1682334) 1 NC_018650.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF 1682334 13693176 O3M_08145 Escherichia coli O104:H4 str. 2009EL-2050 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF YP_006769288.1 1681948 R 1134782 CDS YP_006769289.1 410481743 13693177 complement(1682334..1682669) 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE 1682669 13693177 O3M_08150 Escherichia coli O104:H4 str. 2009EL-2050 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE YP_006769289.1 1682334 R 1134782 CDS YP_006769290.1 410481744 13693178 complement(1682666..1684318) 1 NC_018650.1 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family; 4-amino-4-deoxy-L-arabinose transferase 1684318 arnT 13693178 arnT Escherichia coli O104:H4 str. 2009EL-2050 4-amino-4-deoxy-L-arabinose transferase YP_006769290.1 1682666 R 1134782 CDS YP_006769291.1 410481745 13693179 complement(1684318..1685208) 1 NC_018650.1 COG0726 Predicted xylanase/chitin deacetylase; 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase ArnD 1685208 13693179 O3M_08160 Escherichia coli O104:H4 str. 2009EL-2050 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase ArnD YP_006769291.1 1684318 R 1134782 CDS YP_006769292.1 410481746 13693180 complement(1685205..1687187) 1 NC_018650.1 COG0223 Methionyl-tRNA formyltransferase; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 1687187 13693180 O3M_08165 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_006769292.1 1685205 R 1134782 CDS YP_006769293.1 410481747 13693181 complement(1687187..1688155) 1 NC_018650.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 1688155 13693181 O3M_08170 Escherichia coli O104:H4 str. 2009EL-2050 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_006769293.1 1687187 R 1134782 CDS YP_006769294.1 410481748 13693182 complement(1688159..1689298) 1 NC_018650.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 1689298 13693182 O3M_08175 Escherichia coli O104:H4 str. 2009EL-2050 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_006769294.1 1688159 R 1134782 CDS YP_006769295.1 410481749 13693183 1689606..1690208 1 NC_018650.1 lipopolysaccharide core heptose(II)-phosphate phosphatase 1690208 13693183 O3M_08180 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide core heptose(II)-phosphate phosphatase YP_006769295.1 1689606 D 1134782 CDS YP_006769296.1 410481750 13693184 complement(1690247..1690672) 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; nucleoside triphosphatase NudI 1690672 13693184 O3M_08185 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside triphosphatase NudI YP_006769296.1 1690247 R 1134782 CDS YP_006769297.1 410481751 13693185 1690951..1691493 1 NC_018650.1 outer membrane porin protein 1691493 13693185 O3M_08190 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane porin protein YP_006769297.1 1690951 D 1134782 CDS YP_006769298.1 410481752 13693186 1691593..1692795 1 NC_018650.1 COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; hypothetical protein 1692795 13693186 O3M_08195 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769298.1 1691593 D 1134782 CDS YP_006769299.1 410481753 13693187 1692931..1693320 1 NC_018650.1 COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; 2-keto-3-deoxy-L-rhamnonate aldolase 1693320 13693187 O3M_08200 Escherichia coli O104:H4 str. 2009EL-2050 2-keto-3-deoxy-L-rhamnonate aldolase YP_006769299.1 1692931 D 1134782 CDS YP_006769300.1 410481754 13693188 complement(1693361..1694263) 1 NC_018650.1 COG5464 Uncharacterized conserved protein; hypothetical protein 1694263 13693188 O3M_08205 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769300.1 1693361 R 1134782 CDS YP_006769301.1 410481755 13693189 complement(1694457..1695647) 1 NC_018650.1 COG0247 Fe-S oxidoreductase; sn-glycerol-3-phosphate dehydrogenase subunit C 1695647 glpC 13693189 glpC Escherichia coli O104:H4 str. 2009EL-2050 sn-glycerol-3-phosphate dehydrogenase subunit C YP_006769301.1 1694457 R 1134782 CDS YP_006769302.1 410481756 13693190 complement(1695644..1696903) 1 NC_018650.1 COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; anaerobic glycerol-3-phosphate dehydrogenase subunit B 1696903 13693190 O3M_08215 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_006769302.1 1695644 R 1134782 CDS YP_006769303.1 410481757 13693191 complement(1696893..1698521) 1 NC_018650.1 COG0578 Glycerol-3-phosphate dehydrogenase; sn-glycerol-3-phosphate dehydrogenase subunit A 1698521 glpA 13693191 glpA Escherichia coli O104:H4 str. 2009EL-2050 sn-glycerol-3-phosphate dehydrogenase subunit A YP_006769303.1 1696893 R 1134782 CDS YP_006769304.1 410481758 13693192 1698794..1700152 1 NC_018650.1 COG2271 Sugar phosphate permease; sn-glycerol-3-phosphate transporter 1700152 glpT 13693192 glpT Escherichia coli O104:H4 str. 2009EL-2050 sn-glycerol-3-phosphate transporter YP_006769304.1 1698794 D 1134782 CDS YP_006769305.1 410481759 13693193 1700157..1701233 1 NC_018650.1 COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphodiester phosphodiesterase 1701233 glpQ 13693193 glpQ Escherichia coli O104:H4 str. 2009EL-2050 glycerophosphodiester phosphodiesterase YP_006769305.1 1700157 D 1134782 CDS YP_006769306.1 410481760 13693194 complement(1701275..1701481) 1 NC_018650.1 hypothetical protein 1701481 13693194 O3M_08235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769306.1 1701275 R 1134782 CDS YP_006769307.1 410481761 13693195 1701662..1702642 1 NC_018650.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 1702642 13693195 O3M_08240 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006769307.1 1701662 D 1134782 CDS YP_006769308.1 410481762 13693196 1702896..1703546 1 NC_018650.1 hypothetical protein 1703546 13693196 O3M_08245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769308.1 1702896 D 1134782 CDS YP_006769309.1 410481763 13693197 complement(1703600..1703854) 1 NC_018650.1 COG0633 Ferredoxin; 2Fe-2S ferredoxin 1703854 13693197 O3M_08250 Escherichia coli O104:H4 str. 2009EL-2050 2Fe-2S ferredoxin YP_006769309.1 1703600 R 1134782 CDS YP_006769310.1 410481764 13693198 complement(1703854..1704984) 1 NC_018650.1 COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta 1704984 nrdB 13693198 nrdB Escherichia coli O104:H4 str. 2009EL-2050 ribonucleotide-diphosphate reductase subunit beta YP_006769310.1 1703854 R 1134782 CDS YP_006769311.1 410481765 13693199 complement(1705073..1707358) 1 NC_018650.1 COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha 1707358 13693199 O3M_08260 Escherichia coli O104:H4 str. 2009EL-2050 ribonucleotide-diphosphate reductase subunit alpha YP_006769311.1 1705073 R 1134782 CDS YP_006769312.1 410481766 13693200 1708054..1711788 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; adhesin 1711788 13693200 O3M_08265 Escherichia coli O104:H4 str. 2009EL-2050 adhesin YP_006769312.1 1708054 D 1134782 CDS YP_006769313.1 410481767 13693201 complement(1711916..1712638) 1 NC_018650.1 COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase; bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase 1712638 13693201 O3M_08270 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase YP_006769313.1 1711916 R 1134782 CDS YP_006769314.1 410481768 13693202 1712785..1715412 1 NC_018650.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA gyrase subunit A 1715412 13693202 O3M_08275 Escherichia coli O104:H4 str. 2009EL-2050 DNA gyrase subunit A YP_006769314.1 1712785 D 1134782 CDS YP_006769315.1 410481769 13693203 1715561..1717249 1 NC_018650.1 COG4685 Uncharacterized protein conserved in bacteria; hypothetical protein 1717249 13693203 O3M_08280 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769315.1 1715561 D 1134782 CDS YP_006769316.1 410481770 13693204 1717246..1717869 1 NC_018650.1 COG3234 Uncharacterized protein conserved in bacteria; hypothetical protein 1717869 13693204 O3M_08285 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769316.1 1717246 D 1134782 CDS YP_006769317.1 410481771 13693205 1717803..1722407 1 NC_018650.1 COG2373 Large extracellular alpha-helical protein; alpha-2-macroglobulin family protein 1722407 13693205 O3M_08290 Escherichia coli O104:H4 str. 2009EL-2050 alpha-2-macroglobulin family protein YP_006769317.1 1717803 D 1134782 CDS YP_006769318.1 410481772 13693206 1722408..1724057 1 NC_018650.1 COG5445 Predicted secreted protein; hypothetical protein 1724057 13693206 O3M_08295 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769318.1 1722408 D 1134782 CDS YP_006769319.1 410481773 13693207 1724062..1724838 1 NC_018650.1 COG4676 Uncharacterized protein conserved in bacteria; hypothetical protein 1724838 13693207 O3M_08300 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769319.1 1724062 D 1134782 CDS YP_006769320.1 410481774 13693208 1725113..1727962 1 NC_018650.1 COG0642 Signal transduction histidine kinase; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 1727962 13693208 O3M_08305 Escherichia coli O104:H4 str. 2009EL-2050 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_006769320.1 1725113 D 1134782 CDS YP_006769321.1 410481775 13693209 complement(1728162..1728812) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator RcsB 1728812 13693209 O3M_08310 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator RcsB YP_006769321.1 1728162 R 1134782 CDS YP_006769322.1 410481776 13693210 complement(1728829..1731501) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 1731501 13693210 O3M_08315 Escherichia coli O104:H4 str. 2009EL-2050 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_006769322.1 1728829 R 1134782 CDS YP_006769323.1 410481777 13693211 1732240..1733343 1 NC_018650.1 COG3203 Outer membrane protein (porin); outer membrane porin protein C 1733343 13693211 O3M_08320 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane porin protein C YP_006769323.1 1732240 D 1134782 CDS YP_006769324.1 410481778 13693212 1733455..1734510 1 NC_018650.1 COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; thiamine biosynthesis lipoprotein ApbE 1734510 13693212 O3M_08325 Escherichia coli O104:H4 str. 2009EL-2050 thiamine biosynthesis lipoprotein ApbE YP_006769324.1 1733455 D 1134782 CDS YP_006769325.1 410481779 13693213 1734584..1735648 1 NC_018650.1 COG2169 Adenosine deaminase; bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase 1735648 13693213 O3M_08330 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase YP_006769325.1 1734584 D 1134782 CDS YP_006769326.1 410481780 13693214 1735648..1736298 1 NC_018650.1 COG3145 Alkylated DNA repair protein; alpha-ketoglutarate-dependent dioxygenase AlkB 1736298 13693214 O3M_08335 Escherichia coli O104:H4 str. 2009EL-2050 alpha-ketoglutarate-dependent dioxygenase AlkB YP_006769326.1 1735648 D 1134782 CDS YP_006769327.1 410481781 13693215 1736374..1738017 1 NC_018650.1 COG4615 ABC-type siderophore export system, fused ATPase and permease components; multidrug transporter membrane protein/ATP-binding component 1738017 13693215 O3M_08340 Escherichia coli O104:H4 str. 2009EL-2050 multidrug transporter membrane protein/ATP-binding component YP_006769327.1 1736374 D 1134782 CDS YP_006769328.1 410481782 13693216 1738235..1739881 1 NC_018650.1 COG0579 Predicted dehydrogenase; malate:quinone oxidoreductase 1739881 13693216 O3M_08345 Escherichia coli O104:H4 str. 2009EL-2050 malate:quinone oxidoreductase YP_006769328.1 1738235 D 1134782 CDS YP_006769329.1 410481783 13693217 complement(1740030..1740518) 1 NC_018650.1 COG4574 Serine protease inhibitor ecotin; ecotin 1740518 13693217 O3M_08350 Escherichia coli O104:H4 str. 2009EL-2050 ecotin YP_006769329.1 1740030 R 1134782 CDS YP_006769330.1 410481784 13693218 complement(1740653..1740826) 1 NC_018650.1 COG1626 Neutral trehalase; hypothetical protein 1740826 13693218 O3M_08355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769330.1 1740653 R 1134782 CDS YP_006769331.1 410481785 13693219 1740926..1741420 1 NC_018650.1 COG1145 Ferredoxin; ferredoxin-type protein 1741420 13693219 O3M_08360 Escherichia coli O104:H4 str. 2009EL-2050 ferredoxin-type protein YP_006769331.1 1740926 D 1134782 CDS YP_006769332.1 410481786 13693220 1741410..1741673 1 NC_018650.1 COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase; assembly protein for periplasmic nitrate reductase 1741673 13693220 O3M_08365 Escherichia coli O104:H4 str. 2009EL-2050 assembly protein for periplasmic nitrate reductase YP_006769332.1 1741410 D 1134782 CDS YP_006769333.1 410481787 13693221 1741670..1744156 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; nitrate reductase catalytic subunit 1744156 13693221 O3M_08370 Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase catalytic subunit YP_006769333.1 1741670 D 1134782 CDS YP_006769334.1 410481788 13693222 1744163..1744858 1 NC_018650.1 COG1145 Ferredoxin; quinol dehydrogenase periplasmic component 1744858 napG 13693222 napG Escherichia coli O104:H4 str. 2009EL-2050 quinol dehydrogenase periplasmic component YP_006769334.1 1744163 D 1134782 CDS YP_006769335.1 410481789 13693223 1744845..1745708 1 NC_018650.1 COG0348 Polyferredoxin; quinol dehydrogenase membrane component 1745708 napH 13693223 napH Escherichia coli O104:H4 str. 2009EL-2050 quinol dehydrogenase membrane component YP_006769335.1 1744845 D 1134782 CDS YP_006769336.1 410481790 13693224 1745705..1746154 1 NC_018650.1 COG3043 Nitrate reductase cytochrome c-type subunit; nitrate reductase cytochrome C550 subunit 1746154 napB 13693224 napB Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase cytochrome C550 subunit YP_006769336.1 1745705 D 1134782 CDS YP_006769337.1 410481791 13693225 1746164..1746766 1 NC_018650.1 COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; cytochrome c-type protein NapC 1746766 13693225 O3M_08390 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome c-type protein NapC YP_006769337.1 1746164 D 1134782 CDS YP_006769338.1 410481792 13693226 1746785..1747402 1 NC_018650.1 COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component; cytochrome c biogenesis protein CcmA 1747402 13693226 O3M_08395 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome c biogenesis protein CcmA YP_006769338.1 1746785 D 1134782 CDS YP_006769339.1 410481793 13693227 1747399..1748061 1 NC_018650.1 COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component; Heme exporter protein B 1748061 13693227 O3M_08400 Escherichia coli O104:H4 str. 2009EL-2050 Heme exporter protein B YP_006769339.1 1747399 D 1134782 CDS YP_006769340.1 410481794 13693228 1748103..1748840 1 NC_018650.1 COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; heme exporter protein C 1748840 13693228 O3M_08405 Escherichia coli O104:H4 str. 2009EL-2050 heme exporter protein C YP_006769340.1 1748103 D 1134782 CDS YP_006769341.1 410481795 13693229 1748837..1749046 1 NC_018650.1 COG3114 Heme exporter protein D; cytochrome c biogenesis protein CcmD 1749046 13693229 O3M_08410 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome c biogenesis protein CcmD YP_006769341.1 1748837 D 1134782 CDS YP_006769342.1 410481796 13693230 1749043..1749522 1 NC_018650.1 COG2332 Cytochrome c-type biogenesis protein CcmE; cytochrome c-type biogenesis protein CcmE 1749522 13693230 O3M_08415 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome c-type biogenesis protein CcmE YP_006769342.1 1749043 D 1134782 CDS YP_006769343.1 410481797 13693231 1749519..1751462 1 NC_018650.1 COG1138 Cytochrome c biogenesis factor; heme lyase, CcmF subunit 1751462 13693231 O3M_08420 Escherichia coli O104:H4 str. 2009EL-2050 heme lyase, CcmF subunit YP_006769343.1 1749519 D 1134782 CDS YP_006769344.1 410481798 13693232 1751459..1752016 1 NC_018650.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol:disulfide interchange protein DsbE 1752016 13693232 O3M_08425 Escherichia coli O104:H4 str. 2009EL-2050 thiol:disulfide interchange protein DsbE YP_006769344.1 1751459 D 1134782 CDS YP_006769345.1 410481799 13693233 1752013..1753065 1 NC_018650.1 COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; heme lyase, CcmH subunit 1753065 13693233 O3M_08430 Escherichia coli O104:H4 str. 2009EL-2050 heme lyase, CcmH subunit YP_006769345.1 1752013 D 1134782 CDS YP_006769346.1 410481800 13693234 complement(1753100..1753747) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator NarP 1753747 13693234 O3M_08435 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator NarP YP_006769346.1 1753100 R 1134782 CDS YP_006769347.1 410481801 13693235 1754148..1756433 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; autotransporter 1756433 13693235 O3M_08440 Escherichia coli O104:H4 str. 2009EL-2050 autotransporter YP_006769347.1 1754148 D 1134782 CDS YP_006769348.1 410481802 13693236 1756446..1756658 1 NC_018650.1 autotransporter outer membrane protein 1756658 13693236 O3M_08445 Escherichia coli O104:H4 str. 2009EL-2050 autotransporter outer membrane protein YP_006769348.1 1756446 D 1134782 CDS YP_006769349.1 410481803 13693238 complement(1756912..1758672) 1 NC_018650.1 COG3083 Predicted hydrolase of alkaline phosphatase superfamily; hydrolase, inner membrane 1758672 13693238 O3M_08450 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase, inner membrane YP_006769349.1 1756912 R 1134782 CDS YP_006769350.1 410481804 13693239 complement(1758692..1758919) 1 NC_018650.1 COG3082 Uncharacterized protein conserved in bacteria; hypothetical protein 1758919 13693239 O3M_08455 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769350.1 1758692 R 1134782 CDS YP_006769351.1 410481805 13693240 1759101..1760108 1 NC_018650.1 COG3081 Nucleoid-associated protein; nucleoid-associated protein NdpA 1760108 13693240 O3M_08460 Escherichia coli O104:H4 str. 2009EL-2050 nucleoid-associated protein NdpA YP_006769351.1 1759101 D 1134782 CDS YP_006769352.1 410481806 13693241 complement(1760247..1760531) 1 NC_018650.1 COG1825 Ribosomal protein L25 (general stress protein Ctc); 50S ribosomal protein L25 1760531 13693241 O3M_08465 Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L25 YP_006769352.1 1760247 R 1134782 CDS YP_006769353.1 410481807 13693242 complement(1760656..1762416) 1 NC_018650.1 COG1061 DNA or RNA helicases of superfamily II; nucleic acid ATP-dependent helicase 1762416 13693242 O3M_08470 Escherichia coli O104:H4 str. 2009EL-2050 nucleic acid ATP-dependent helicase YP_006769353.1 1760656 R 1134782 CDS YP_006769354.1 410481808 13693243 1762565..1763260 1 NC_018650.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA pseudouridylate synthase A 1763260 13693243 O3M_08475 Escherichia coli O104:H4 str. 2009EL-2050 16S rRNA pseudouridylate synthase A YP_006769354.1 1762565 D 1134782 CDS YP_006769355.1 410481809 13693244 1763288..1764478 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; bicyclomycin/multidrug efflux system protein 1764478 13693244 O3M_08480 Escherichia coli O104:H4 str. 2009EL-2050 bicyclomycin/multidrug efflux system protein YP_006769355.1 1763288 D 1134782 CDS YP_006769356.1 410481810 13693245 1764811..1765155 1 NC_018650.1 hypothetical protein 1765155 13693245 O3M_08485 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769356.1 1764811 D 1134782 CDS YP_006769357.1 410481811 13693246 complement(1765159..1766748) 1 NC_018650.1 COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; microcin C ABC transporter ATP-binding protein YejF 1766748 13693246 O3M_08490 Escherichia coli O104:H4 str. 2009EL-2050 microcin C ABC transporter ATP-binding protein YejF YP_006769357.1 1765159 R 1134782 CDS YP_006769358.1 410481812 13693247 complement(1766750..1767775) 1 NC_018650.1 COG4239 ABC-type uncharacterized transport system, permease component; microcin C ABC transporter permease 1767775 13693247 O3M_08495 Escherichia coli O104:H4 str. 2009EL-2050 microcin C ABC transporter permease YP_006769358.1 1766750 R 1134782 CDS YP_006769359.1 410481813 13693248 complement(1767775..1768869) 1 NC_018650.1 COG4174 ABC-type uncharacterized transport system, permease component; microcin C ABC transporter permease YejB 1768869 13693248 O3M_08500 Escherichia coli O104:H4 str. 2009EL-2050 microcin C ABC transporter permease YejB YP_006769359.1 1767775 R 1134782 CDS YP_006769360.1 410481814 13693249 complement(1768870..1770684) 1 NC_018650.1 periplasmic-binding component of ABC superfamily transporter; COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide transporter subunit 1770684 13693249 O3M_08505 Escherichia coli O104:H4 str. 2009EL-2050 oligopeptide transporter subunit YP_006769360.1 1768870 R 1134782 CDS YP_006769361.1 410481815 13693250 complement(1770766..1772322) 1 NC_018650.1 COG2200 FOG: EAL domain; phage resistance protein 1772322 13693250 O3M_08510 Escherichia coli O104:H4 str. 2009EL-2050 phage resistance protein YP_006769361.1 1770766 R 1134782 CDS YP_006769362.1 410481816 13693251 complement(1772503..1773069) 1 NC_018650.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); outer membrane lipoprotein 1773069 spr 13693251 spr Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006769362.1 1772503 R 1134782 CDS YP_006769363.1 410481817 13693252 complement(1773481..1774194) 1 NC_018650.1 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 1774194 13693252 O3M_08520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769363.1 1773481 R 1134782 CDS YP_006769364.1 410481818 13693253 complement(1774233..1775219) 1 NC_018650.1 COG0523 Putative GTPases (G3E family); hypothetical protein 1775219 13693253 O3M_08525 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769364.1 1774233 R 1134782 CDS YP_006769365.1 410481819 13693254 complement(1775337..1776803) 1 NC_018650.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; sugar dehydrogenase, NAD-dependent 1776803 13693254 O3M_08530 Escherichia coli O104:H4 str. 2009EL-2050 sugar dehydrogenase, NAD-dependent YP_006769365.1 1775337 R 1134782 CDS YP_006769366.1 410481820 13693255 complement(1777026..1777598) 1 NC_018650.1 COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); elongation factor P 1777598 13693255 O3M_08535 Escherichia coli O104:H4 str. 2009EL-2050 elongation factor P YP_006769366.1 1777026 R 1134782 CDS YP_006769367.1 410481821 13693256 1777753..1778007 1 NC_018650.1 COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 1778007 13693256 O3M_08540 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769367.1 1777753 D 1134782 CDS YP_006769368.1 410481822 13693257 complement(1778004..1779185) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; sugar efflux transporter B 1779185 13693257 O3M_08545 Escherichia coli O104:H4 str. 2009EL-2050 sugar efflux transporter B YP_006769368.1 1778004 R 1134782 CDS YP_006769369.1 410481823 13693258 1779553..1780683 1 NC_018650.1 COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; PTS system fructose-specific transporter subunit IIA/HPr protein 1780683 13693258 O3M_08550 Escherichia coli O104:H4 str. 2009EL-2050 PTS system fructose-specific transporter subunit IIA/HPr protein YP_006769369.1 1779553 D 1134782 CDS YP_006769370.1 410481824 13693259 1780683..1781621 1 NC_018650.1 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); 1-phosphofructokinase 1781621 fruK 13693259 fruK Escherichia coli O104:H4 str. 2009EL-2050 1-phosphofructokinase YP_006769370.1 1780683 D 1134782 CDS YP_006769371.1 410481825 13693260 1781638..1783329 1 NC_018650.1 COG3925 N-terminal domain of the phosphotransferase system fructose-specific component IIB; PTS system fructose-specific transporter subunit IIBC 1783329 13693260 O3M_08560 Escherichia coli O104:H4 str. 2009EL-2050 PTS system fructose-specific transporter subunit IIBC YP_006769371.1 1781638 D 1134782 CDS YP_006769372.1 410481826 13693261 1783753..1784694 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; pseudouridine kinase 1784694 13693261 O3M_08565 Escherichia coli O104:H4 str. 2009EL-2050 pseudouridine kinase YP_006769372.1 1783753 D 1134782 CDS YP_006769373.1 410481827 13693262 1784682..1785620 1 NC_018650.1 COG2313 Uncharacterized enzyme involved in pigment biosynthesis; hypothetical protein 1785620 13693262 O3M_08570 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769373.1 1784682 D 1134782 CDS YP_006769374.1 410481828 13693263 1785714..1786964 1 NC_018650.1 COG1972 Nucleoside permease; sodium/proton nucleoside transporter 1786964 13693263 O3M_08575 Escherichia coli O104:H4 str. 2009EL-2050 sodium/proton nucleoside transporter YP_006769374.1 1785714 D 1134782 CDS YP_006769375.1 410481829 13693264 complement(1787032..1787691) 1 NC_018650.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; DNA-binding transcriptional activator YeiL 1787691 13693264 O3M_08580 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator YeiL YP_006769375.1 1787032 R 1134782 CDS YP_006769376.1 410481830 13693265 1787860..1788801 1 NC_018650.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase 2 1788801 rihB 13693265 rihB Escherichia coli O104:H4 str. 2009EL-2050 ribonucleoside hydrolase 2 YP_006769376.1 1787860 D 1134782 CDS YP_006769377.1 410481831 13693266 1788901..1790151 1 NC_018650.1 COG1972 Nucleoside permease; nucleoside transporter 1790151 13693266 O3M_08590 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside transporter YP_006769377.1 1788901 D 1134782 CDS YP_006769378.1 410481832 13693267 complement(1790207..1791295) 1 NC_018650.1 COG2771 DNA-binding HTH domain-containing proteins; kinase 1791295 13693267 O3M_08595 Escherichia coli O104:H4 str. 2009EL-2050 kinase YP_006769378.1 1790207 R 1134782 CDS YP_006769379.1 410481833 13693268 complement(1791299..1792156) 1 NC_018650.1 COG0648 Endonuclease IV; endonuclease IV 1792156 13693268 O3M_08600 Escherichia coli O104:H4 str. 2009EL-2050 endonuclease IV YP_006769379.1 1791299 R 1134782 CDS YP_006769380.1 410481834 13693269 complement(1792230..1793279) 1 NC_018650.1 COG2855 Predicted membrane protein; hypothetical protein 1793279 13693269 O3M_08605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769380.1 1792230 R 1134782 CDS YP_006769381.1 410481835 13693270 1793378..1794259 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 1794259 13693270 O3M_08610 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006769381.1 1793378 D 1134782 CDS YP_006769382.1 410481836 13693271 1794464..1795933 1 NC_018650.1 COG0833 Amino acid transporters; lysine transporter 1795933 13693271 O3M_08615 Escherichia coli O104:H4 str. 2009EL-2050 lysine transporter YP_006769382.1 1794464 D 1134782 CDS YP_006769383.1 410481837 13693272 1796226..1798217 1 NC_018650.1 COG4771 Outer membrane receptor for ferrienterochelin and colicins; catecholate siderophore receptor CirA 1798217 13693272 O3M_08620 Escherichia coli O104:H4 str. 2009EL-2050 catecholate siderophore receptor CirA YP_006769383.1 1796226 D 1134782 CDS YP_006769384.1 410481838 13693273 complement(1798249..1799085) 1 NC_018650.1 COG0627 Predicted esterase; esterase 1799085 13693273 O3M_08625 Escherichia coli O104:H4 str. 2009EL-2050 esterase YP_006769384.1 1798249 R 1134782 CDS YP_006769385.1 410481839 13693274 1799343..1800011 1 NC_018650.1 COG0302 GTP cyclohydrolase I; GTP cyclohydrolase I 1800011 folE 13693274 folE Escherichia coli O104:H4 str. 2009EL-2050 GTP cyclohydrolase I YP_006769385.1 1799343 D 1134782 CDS YP_006769386.1 410481840 13693275 1800028..1801185 1 NC_018650.1 COG2311 Predicted membrane protein; hypothetical protein 1801185 13693275 O3M_08635 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769386.1 1800028 D 1134782 CDS YP_006769387.1 410481841 13693276 1801327..1802367 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional regulator GalS 1802367 13693276 O3M_08640 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator GalS YP_006769387.1 1801327 D 1134782 CDS YP_006769388.1 410481842 13693277 1802647..1803645 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; methyl-galactoside ABC transporter substrate-binding protein MglB 1803645 13693277 O3M_08645 Escherichia coli O104:H4 str. 2009EL-2050 methyl-galactoside ABC transporter substrate-binding protein MglB YP_006769388.1 1802647 D 1134782 CDS YP_006769389.1 410481843 13693278 1803706..1805226 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; galactose/methyl galaxtoside transporter ATP-binding protein 1805226 13693278 O3M_08650 Escherichia coli O104:H4 str. 2009EL-2050 galactose/methyl galaxtoside transporter ATP-binding protein YP_006769389.1 1803706 D 1134782 CDS YP_006769390.1 410481844 13693279 1805242..1806252 1 NC_018650.1 COG4211 ABC-type glucose/galactose transport system, permease component; beta-methylgalactoside transporter inner membrane protein 1806252 mglC 13693279 mglC Escherichia coli O104:H4 str. 2009EL-2050 beta-methylgalactoside transporter inner membrane protein YP_006769390.1 1805242 D 1134782 CDS YP_006769391.1 410481845 13693280 complement(1806323..1807558) 1 NC_018650.1 COG0167 Dihydroorotate dehydrogenase; dihydropyrimidine dehydrogenase subunit B 1807558 13693280 O3M_08660 Escherichia coli O104:H4 str. 2009EL-2050 dihydropyrimidine dehydrogenase subunit B YP_006769391.1 1806323 R 1134782 CDS YP_006769392.1 410481846 13693281 complement(1807552..1808790) 1 NC_018650.1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; dihydropyrimidine dehydrogenase subunit A 1808790 13693281 O3M_08665 Escherichia coli O104:H4 str. 2009EL-2050 dihydropyrimidine dehydrogenase subunit A YP_006769392.1 1807552 R 1134782 CDS YP_006769393.1 410481847 13693282 complement(1809109..1809348) 1 NC_018650.1 hypothetical protein 1809348 13693282 O3M_08670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769393.1 1809109 R 1134782 CDS YP_006769394.1 410481848 13693283 complement(1809351..1810070) 1 NC_018650.1 COG2949 Uncharacterized membrane protein; vancomycin high temperature exclusion protein 1810070 13693283 O3M_08675 Escherichia coli O104:H4 str. 2009EL-2050 vancomycin high temperature exclusion protein YP_006769394.1 1809351 R 1134782 CDS YP_006769395.1 410481849 13693284 complement(1810220..1811104) 1 NC_018650.1 COG0295 Cytidine deaminase; cytidine deaminase 1811104 13693284 O3M_08680 Escherichia coli O104:H4 str. 2009EL-2050 cytidine deaminase YP_006769395.1 1810220 R 1134782 CDS YP_006769396.1 410481850 13693285 complement(1811234..1811929) 1 NC_018650.1 COG1346 Putative effector of murein hydrolase; hypothetical protein 1811929 13693285 O3M_08685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769396.1 1811234 R 1134782 CDS YP_006769397.1 410481851 13693286 complement(1811926..1812324) 1 NC_018650.1 COG1380 Putative effector of murein hydrolase LrgA; hypothetical protein 1812324 13693286 O3M_08690 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769397.1 1811926 R 1134782 CDS YP_006769398.1 410481852 13693287 1812563..1813510 1 NC_018650.1 COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase C 1813510 13693287 O3M_08695 Escherichia coli O104:H4 str. 2009EL-2050 tRNA-dihydrouridine synthase C YP_006769398.1 1812563 D 1134782 CDS YP_006769399.1 410481853 13693288 complement(1813883..1813966) 1 NC_018650.1 hypothetical protein 1813966 13693288 O3M_08700 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769399.1 1813883 R 1134782 CDS YP_006769400.1 410481854 13693289 1814190..1815626 1 NC_018650.1 COG1538 Outer membrane protein; multidrug resistance outer membrane protein MdtQ 1815626 13693289 O3M_08705 Escherichia coli O104:H4 str. 2009EL-2050 multidrug resistance outer membrane protein MdtQ YP_006769400.1 1814190 D 1134782 CDS YP_006769401.1 410481855 13693290 1815679..1816440 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1816440 13693290 O3M_08710 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006769401.1 1815679 D 1134782 CDS YP_006769402.1 410481856 13693291 complement(1816570..1817148) 1 NC_018650.1 COG0586 Uncharacterized membrane-associated protein; inner membrane protein 1817148 13693291 O3M_08715 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769402.1 1816570 R 1134782 CDS YP_006769403.1 410481857 13693292 1817318..1817905 1 NC_018650.1 inner membrane protein YohC 1817905 13693292 O3M_08720 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YohC YP_006769403.1 1817318 D 1134782 CDS YP_006769404.1 410481858 13693293 1818079..1819011 1 NC_018650.1 COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine endopeptidase 1819011 pbpG 13693293 pbpG Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-D-alanine endopeptidase YP_006769404.1 1818079 D 1134782 CDS YP_006769405.1 410481859 13693294 complement(1819049..1820764) 1 NC_018650.1 COG0277 FAD/FMN-containing dehydrogenases; D-lactate dehydrogenase 1820764 13693294 O3M_08730 Escherichia coli O104:H4 str. 2009EL-2050 D-lactate dehydrogenase YP_006769405.1 1819049 R 1134782 CDS YP_006769406.1 410481860 13693295 1820960..1823257 1 NC_018650.1 COG1472 Beta-glucosidase-related glycosidases; beta-D-glucoside glucohydrolase 1823257 13693295 O3M_08735 Escherichia coli O104:H4 str. 2009EL-2050 beta-D-glucoside glucohydrolase YP_006769406.1 1820960 D 1134782 CDS YP_006769407.1 410481861 13693296 1823468..1824385 1 NC_018650.1 COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); transporter subunit 1824385 13693296 O3M_08740 Escherichia coli O104:H4 str. 2009EL-2050 transporter subunit YP_006769407.1 1823468 D 1134782 CDS YP_006769408.1 410481862 13693297 1824392..1825549 1 NC_018650.1 COG1174 ABC-type proline/glycine betaine transport systems, permease component; transporter subunit 1825549 13693297 O3M_08745 Escherichia coli O104:H4 str. 2009EL-2050 transporter subunit YP_006769408.1 1824392 D 1134782 CDS YP_006769409.1 410481863 13693298 1825542..1826468 1 NC_018650.1 COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; ABC transporter ATP-binding protein 1826468 13693298 O3M_08750 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006769409.1 1825542 D 1134782 CDS YP_006769410.1 410481864 13693299 1826473..1827204 1 NC_018650.1 COG1174 ABC-type proline/glycine betaine transport systems, permease component; quaternare amine family ABC transporter permease 1827204 13693299 O3M_08755 Escherichia coli O104:H4 str. 2009EL-2050 quaternare amine family ABC transporter permease YP_006769410.1 1826473 D 1134782 CDS YP_006769411.1 410481865 13693300 complement(1827185..1827292) 1 NC_018650.1 hypothetical protein 1827292 13693300 O3M_08760 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769411.1 1827185 R 1134782 CDS YP_006769412.1 410481866 13693301 complement(1827352..1828083) 1 NC_018650.1 COG0789 Predicted transcriptional regulators; transcriptional regulator MirA 1828083 13693301 O3M_08765 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator MirA YP_006769412.1 1827352 R 1134782 CDS YP_006769413.1 410481867 13693302 1828305..1829990 1 NC_018650.1 COG3275 Putative regulator of cell autolysis; sensory kinase in two-component system with YehT 1829990 13693302 O3M_08770 Escherichia coli O104:H4 str. 2009EL-2050 sensory kinase in two-component system with YehT YP_006769413.1 1828305 D 1134782 CDS YP_006769414.1 410481868 13693303 1829987..1830706 1 NC_018650.1 COG3279 Response regulator of the LytR/AlgR family; two-component response-regulatory protein YehT 1830706 13693303 O3M_08775 Escherichia coli O104:H4 str. 2009EL-2050 two-component response-regulatory protein YehT YP_006769414.1 1829987 D 1134782 CDS YP_006769415.1 410481869 13693304 1830753..1831223 1 NC_018650.1 COG4807 Uncharacterized protein conserved in bacteria; hypothetical protein 1831223 13693304 O3M_08780 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769415.1 1830753 D 1134782 CDS YP_006769416.1 410481870 13693305 complement(1831264..1831725) 1 NC_018650.1 COG4808 Uncharacterized protein conserved in bacteria; hypothetical protein 1831725 13693305 O3M_08785 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769416.1 1831264 R 1134782 CDS YP_006769417.1 410481871 13693306 complement(1831850..1833850) 1 NC_018650.1 hypothetical protein 1833850 13693306 O3M_08790 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769417.1 1831850 R 1134782 CDS YP_006769418.1 410481872 13693307 complement(1833847..1834983) 1 NC_018650.1 hypothetical protein 1834983 13693307 O3M_08795 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769418.1 1833847 R 1134782 CDS YP_006769419.1 410481873 13693308 complement(1834976..1837255) 1 NC_018650.1 hypothetical protein 1837255 13693308 O3M_08800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769419.1 1834976 R 1134782 CDS YP_006769420.1 410481874 13693309 complement(1837266..1838354) 1 NC_018650.1 COG0714 MoxR-like ATPases; transporter subunit 1838354 13693309 O3M_08805 Escherichia coli O104:H4 str. 2009EL-2050 transporter subunit YP_006769420.1 1837266 R 1134782 CDS YP_006769421.1 410481875 13693310 1839395..1839484 1 NC_018650.1 hypothetical protein 1839484 13693310 O3M_08810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769421.1 1839395 D 1134782 CDS YP_006769422.1 410481876 13693311 complement(1839972..1843604) 1 NC_018650.1 hypothetical protein 1843604 13693311 O3M_08815 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769422.1 1839972 R 1134782 CDS YP_006769423.1 410481877 13693312 complement(1843614..1847408) 1 NC_018650.1 COG3831 Uncharacterized conserved protein; hypothetical protein 1847408 13693312 O3M_08820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769423.1 1843614 R 1134782 CDS YP_006769424.1 410481878 13693313 complement(1847549..1849582) 1 NC_018650.1 COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase 1849582 metG 13693313 metG Escherichia coli O104:H4 str. 2009EL-2050 methionyl-tRNA synthetase YP_006769424.1 1847549 R 1134782 CDS YP_006769425.1 410481879 13693314 1849714..1850823 1 NC_018650.1 COG0489 ATPases involved in chromosome partitioning; antiporter inner membrane protein 1850823 13693314 O3M_08830 Escherichia coli O104:H4 str. 2009EL-2050 antiporter inner membrane protein YP_006769425.1 1849714 D 1134782 CDS YP_006769426.1 410481880 13693315 1851086..1851367 1 NC_018650.1 hypothetical protein 1851367 13693315 O3M_08835 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769426.1 1851086 D 1134782 CDS YP_006769427.1 410481881 13693316 1851660..1852202 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like protein 1852202 13693316 O3M_08840 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like protein YP_006769427.1 1851660 D 1134782 CDS YP_006769428.1 410481882 13693317 1852283..1852957 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; membrane-associated pilin chaperone 1852957 13693317 O3M_08845 Escherichia coli O104:H4 str. 2009EL-2050 membrane-associated pilin chaperone YP_006769428.1 1852283 D 1134782 CDS YP_006769429.1 410481883 13693318 1852973..1855453 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 1855453 13693318 O3M_08850 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial outer membrane usher protein YP_006769429.1 1852973 D 1134782 CDS YP_006769430.1 410481884 13693319 1855484..1856134 1 NC_018650.1 fimbrial-like adhesin protein StcD 1856134 13693319 O3M_08855 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein StcD YP_006769430.1 1855484 D 1134782 CDS YP_006769431.1 410481885 13693320 1856185..1856460 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 1856460 13693320 O3M_08860 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006769431.1 1856185 D 1134782 CDS YP_006769432.1 410481886 13693321 1856379..1856882 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 1856882 13693321 O3M_08865 Escherichia coli O104:H4 str. 2009EL-2050 transposase InsB IS1 YP_006769432.1 1856379 D 1134782 CDS YP_006769433.1 410481887 13693322 1856984..1857280 1 NC_018650.1 fimbrial-like adhesin protein StcD 1857280 13693322 O3M_08870 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein StcD YP_006769433.1 1856984 D 1134782 CDS YP_006769434.1 410481888 13693323 complement(1857362..1857700) 1 NC_018650.1 COG5455 Predicted integral membrane protein; hypothetical protein 1857700 13693323 O3M_08875 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769434.1 1857362 R 1134782 CDS YP_006769435.1 410481889 13693324 complement(1857919..1858743) 1 NC_018650.1 COG2215 ABC-type uncharacterized transport system, permease component; nickel/cobalt efflux protein RcnA 1858743 13693324 O3M_08880 Escherichia coli O104:H4 str. 2009EL-2050 nickel/cobalt efflux protein RcnA YP_006769435.1 1857919 R 1134782 CDS YP_006769436.1 410481890 13693325 1858864..1859136 1 NC_018650.1 COG1937 Uncharacterized protein conserved in bacteria; transcriptional repressor RcnR to maintain nickel and cobalt homeostasis 1859136 13693325 O3M_08885 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional repressor RcnR to maintain nickel and cobalt homeostasis YP_006769436.1 1858864 D 1134782 CDS YP_006769437.1 410481891 13693326 1859359..1860147 1 NC_018650.1 COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 1860147 13693326 O3M_08890 Escherichia coli O104:H4 str. 2009EL-2050 hydroxyethylthiazole kinase YP_006769437.1 1859359 D 1134782 CDS YP_006769438.1 410481892 13693327 1860144..1860944 1 NC_018650.1 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase 1860944 13693327 O3M_08895 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase YP_006769438.1 1860144 D 1134782 CDS YP_006769439.1 410481893 13693328 1861009..1861827 1 NC_018650.1 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); hydrolase 1861827 13693328 O3M_08900 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006769439.1 1861009 D 1134782 CDS YP_006769440.1 410481894 13693329 1861879..1862625 1 NC_018650.1 COG2188 Transcriptional regulators; GntR family transcriptional regulator 1862625 13693329 O3M_08905 Escherichia coli O104:H4 str. 2009EL-2050 GntR family transcriptional regulator YP_006769440.1 1861879 D 1134782 CDS YP_006769441.1 410481895 13693330 complement(1862599..1863564) 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; kinase 1863564 13693330 O3M_08910 Escherichia coli O104:H4 str. 2009EL-2050 kinase YP_006769441.1 1862599 R 1134782 CDS YP_006769442.1 410481896 13693331 complement(1863561..1864565) 1 NC_018650.1 COG1397 ADP-ribosylglycohydrolase; (phospho)hydrolase 1864565 13693331 O3M_08915 Escherichia coli O104:H4 str. 2009EL-2050 (phospho)hydrolase YP_006769442.1 1863561 R 1134782 CDS YP_006769443.1 410481897 13693332 complement(1864562..1865839) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; nucleoside transporter 1865839 13693332 O3M_08920 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside transporter YP_006769443.1 1864562 R 1134782 CDS YP_006769444.1 410481898 13693333 1866096..1867148 1 NC_018650.1 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes; fructose-bisphosphate aldolase 1867148 13693333 O3M_08925 Escherichia coli O104:H4 str. 2009EL-2050 fructose-bisphosphate aldolase YP_006769444.1 1866096 D 1134782 CDS YP_006769445.1 410481899 13693334 1867458..1868312 1 NC_018650.1 COG0191 Fructose/tagatose bisphosphate aldolase; tagatose-bisphosphate aldolase 1868312 gatY 13693334 gatY Escherichia coli O104:H4 str. 2009EL-2050 tagatose-bisphosphate aldolase YP_006769445.1 1867458 D 1134782 CDS YP_006769446.1 410481900 13693335 1869608..1870060 1 NC_018650.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system galactitol-specific transporter subunit IIA 1870060 13693335 O3M_08945 Escherichia coli O104:H4 str. 2009EL-2050 PTS system galactitol-specific transporter subunit IIA YP_006769446.1 1869608 D 1134782 CDS YP_006769447.1 410481901 13693336 1870091..1870375 1 NC_018650.1 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB 1870375 13693336 O3M_08950 Escherichia coli O104:H4 str. 2009EL-2050 PTS system galactitol-specific transporter subunit IIB YP_006769447.1 1870091 D 1134782 CDS YP_006769448.1 410481902 13693337 1870379..1871734 1 NC_018650.1 COG3775 Phosphotransferase system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1871734 13693337 O3M_08955 Escherichia coli O104:H4 str. 2009EL-2050 PTS system galactitol-specific transporter subunit IIC YP_006769448.1 1870379 D 1134782 CDS YP_006769449.1 410481903 13693338 1871782..1872822 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; galactitol-1-phosphate dehydrogenase 1872822 13693338 O3M_08960 Escherichia coli O104:H4 str. 2009EL-2050 galactitol-1-phosphate dehydrogenase YP_006769449.1 1871782 D 1134782 CDS YP_006769450.1 410481904 13693339 1872928..1873701 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; galactitol utilization operon repressor 1873701 13693339 O3M_08965 Escherichia coli O104:H4 str. 2009EL-2050 galactitol utilization operon repressor YP_006769450.1 1872928 D 1134782 CDS YP_006769451.1 410481905 13693340 complement(1873783..1874682) 1 NC_018650.1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; lipid kinase 1874682 13693340 O3M_08970 Escherichia coli O104:H4 str. 2009EL-2050 lipid kinase YP_006769451.1 1873783 R 1134782 CDS YP_006769452.1 410481906 13693341 1875097..1875414 1 NC_018650.1 hypothetical protein 1875414 13693341 O3M_08975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769452.1 1875097 D 1134782 CDS YP_006769453.1 410481907 13693342 complement(1875744..1877105) 1 NC_018650.1 COG0826 Collagenase and related proteases; protease 1877105 13693342 O3M_08980 Escherichia coli O104:H4 str. 2009EL-2050 protease YP_006769453.1 1875744 R 1134782 CDS YP_006769454.1 410481908 13693343 complement(1877208..1877504) 1 NC_018650.1 COG3668 Plasmid stabilization system protein; plasmid stabilization system protein 1877504 13693343 O3M_08985 Escherichia coli O104:H4 str. 2009EL-2050 plasmid stabilization system protein YP_006769454.1 1877208 R 1134782 CDS YP_006769455.1 410481909 13693344 complement(1877506..1877802) 1 NC_018650.1 COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain; transcriptional regulator 1877802 13693344 O3M_08990 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006769455.1 1877506 R 1134782 CDS YP_006769456.1 410481910 13693345 complement(1878011..1878343) 1 NC_018650.1 COG3422 Uncharacterized conserved protein; hypothetical protein 1878343 13693345 O3M_08995 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769456.1 1878011 R 1134782 CDS YP_006769457.1 410481911 13693346 complement(1878534..1879256) 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator BaeR 1879256 13693346 O3M_09000 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator BaeR YP_006769457.1 1878534 R 1134782 CDS YP_006769458.1 410481912 13693347 complement(1879253..1880656) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; signal transduction histidine-protein kinase BaeS 1880656 13693347 O3M_09005 Escherichia coli O104:H4 str. 2009EL-2050 signal transduction histidine-protein kinase BaeS YP_006769458.1 1879253 R 1134782 CDS YP_006769459.1 410481913 13693348 complement(1880653..1882068) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 1882068 13693348 O3M_09010 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769459.1 1880653 R 1134782 CDS YP_006769460.1 410481914 13693349 complement(1882069..1885146) 1 NC_018650.1 COG0841 Cation/multidrug efflux pump; multidrug efflux system subunit MdtC 1885146 13693349 O3M_09015 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system subunit MdtC YP_006769460.1 1882069 R 1134782 CDS YP_006769461.1 410481915 13693350 complement(1885147..1888269) 1 NC_018650.1 COG0841 Cation/multidrug efflux pump; multidrug efflux system subunit MdtB 1888269 13693350 O3M_09020 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system subunit MdtB YP_006769461.1 1885147 R 1134782 CDS YP_006769462.1 410481916 13693351 complement(1888269..1889516) 1 NC_018650.1 COG0845 Membrane-fusion protein; multidrug efflux system subunit MdtA 1889516 13693351 O3M_09025 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system subunit MdtA YP_006769462.1 1888269 R 1134782 CDS YP_006769463.1 410481917 13693352 1890732..1891391 1 NC_018650.1 COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; hypothetical protein 1891391 13693352 O3M_09030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769463.1 1890732 D 1134782 CDS YP_006769464.1 410481918 13693353 1891388..1892149 1 NC_018650.1 hypothetical protein 1892149 13693353 O3M_09035 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769464.1 1891388 D 1134782 CDS YP_006769465.1 410481919 13693354 1892146..1894086 1 NC_018650.1 COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains; hypothetical protein 1894086 13693354 O3M_09040 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769465.1 1892146 D 1134782 CDS YP_006769466.1 410481920 13693355 complement(1894098..1895450) 1 NC_018650.1 COG0443 Molecular chaperone; chaperone 1895450 13693355 O3M_09045 Escherichia coli O104:H4 str. 2009EL-2050 chaperone YP_006769466.1 1894098 R 1134782 CDS YP_006769467.1 410481921 13693356 1895584..1896441 1 NC_018650.1 COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; 3-methyladenine DNA glycosylase 1896441 13693356 O3M_09050 Escherichia coli O104:H4 str. 2009EL-2050 3-methyladenine DNA glycosylase YP_006769467.1 1895584 D 1134782 CDS YP_006769468.1 410481922 13693357 complement(1896480..1899797) 1 NC_018650.1 COG2202 FOG: PAS/PAC domain; diguanylate cyclase 1899797 13693357 O3M_09055 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006769468.1 1896480 R 1134782 CDS YP_006769469.1 410481923 13693358 1900115..1900756 1 NC_018650.1 COG0572 Uridine kinase; uridine/cytidine kinase 1900756 13693358 O3M_09060 Escherichia coli O104:H4 str. 2009EL-2050 uridine/cytidine kinase YP_006769469.1 1900115 D 1134782 CDS YP_006769470.1 410481924 13693359 1900848..1901429 1 NC_018650.1 COG0717 Deoxycytidine deaminase; deoxycytidine triphosphate deaminase 1901429 dcd 13693359 dcd Escherichia coli O104:H4 str. 2009EL-2050 deoxycytidine triphosphate deaminase YP_006769470.1 1900848 D 1134782 CDS YP_006769471.1 410481925 13693360 1901451..1903304 1 NC_018650.1 COG2982 Uncharacterized protein involved in outer membrane biogenesis; assembly protein 1903304 13693360 O3M_09070 Escherichia coli O104:H4 str. 2009EL-2050 assembly protein YP_006769471.1 1901451 D 1134782 CDS YP_006769472.1 410481926 13693361 complement(1903578..1905161) 1 NC_018650.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 1905161 13693361 O3M_09075 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769472.1 1903578 R 1134782 CDS YP_006769473.1 410481927 13693362 1905820..1906959 1 NC_018650.1 COG1596 Periplasmic protein involved in polysaccharide export; polysaccharide export protein Wza 1906959 13693362 O3M_09080 Escherichia coli O104:H4 str. 2009EL-2050 polysaccharide export protein Wza YP_006769473.1 1905820 D 1134782 CDS YP_006769474.1 410481928 13693363 1906965..1907408 1 NC_018650.1 COG0394 Protein-tyrosine-phosphatase; tyrosine phosphatase 1907408 13693363 O3M_09085 Escherichia coli O104:H4 str. 2009EL-2050 tyrosine phosphatase YP_006769474.1 1906965 D 1134782 CDS YP_006769475.1 410481929 13693364 1907411..1909573 1 NC_018650.1 COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; tyrosine kinase 1909573 13693364 O3M_09090 Escherichia coli O104:H4 str. 2009EL-2050 tyrosine kinase YP_006769475.1 1907411 D 1134782 CDS YP_006769476.1 410481930 13693365 1909751..1910590 1 NC_018650.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1910590 13693365 O3M_09095 Escherichia coli O104:H4 str. 2009EL-2050 glycosyl transferase family protein YP_006769476.1 1909751 D 1134782 CDS YP_006769477.1 410481931 13693366 1910593..1911081 1 NC_018650.1 COG1045 Serine acetyltransferase; acyl transferase 1911081 13693366 O3M_09100 Escherichia coli O104:H4 str. 2009EL-2050 acyl transferase YP_006769477.1 1910593 D 1134782 CDS YP_006769478.1 410481932 13693367 1911078..1912295 1 NC_018650.1 COG0438 Glycosyltransferase; glycosyl transferase family protein 1912295 13693367 O3M_09105 Escherichia coli O104:H4 str. 2009EL-2050 glycosyl transferase family protein YP_006769478.1 1911078 D 1134782 CDS YP_006769479.1 410481933 13693368 1912270..1913487 1 NC_018650.1 colanic acid biosynthesis protein 1913487 wcaD 13693368 wcaD Escherichia coli O104:H4 str. 2009EL-2050 colanic acid biosynthesis protein YP_006769479.1 1912270 D 1134782 CDS YP_006769480.1 410481934 13693369 1913498..1914244 1 NC_018650.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1914244 13693369 O3M_09115 Escherichia coli O104:H4 str. 2009EL-2050 glycosyl transferase family protein YP_006769480.1 1913498 D 1134782 CDS YP_006769481.1 410481935 13693370 1914260..1914808 1 NC_018650.1 COG0110 Acetyltransferase (isoleucine patch superfamily); acyl transferase 1914808 13693370 O3M_09120 Escherichia coli O104:H4 str. 2009EL-2050 acyl transferase YP_006769481.1 1914260 D 1134782 CDS YP_006769482.1 410481936 13693371 1914835..1915956 1 NC_018650.1 COG1089 GDP-D-mannose dehydratase; GDP-mannose 4,6-dehydratase 1915956 13693371 O3M_09125 Escherichia coli O104:H4 str. 2009EL-2050 GDP-mannose 4,6-dehydratase YP_006769482.1 1914835 D 1134782 CDS YP_006769483.1 410481937 13693372 1915959..1916924 1 NC_018650.1 COG0451 Nucleoside-diphosphate-sugar epimerases; bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/GDP-4-dehydro-6-L-deoxygalactose reductase 1916924 13693372 O3M_09130 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/GDP-4-dehydro-6-L-deoxygalactose reductase YP_006769483.1 1915959 D 1134782 CDS YP_006769484.1 410481938 13693373 1916927..1917406 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; GDP-mannose mannosyl hydrolase 1917406 13693373 O3M_09135 Escherichia coli O104:H4 str. 2009EL-2050 GDP-mannose mannosyl hydrolase YP_006769484.1 1916927 D 1134782 CDS YP_006769485.1 410481939 13693374 1917403..1918626 1 NC_018650.1 COG0438 Glycosyltransferase; glycosyl transferase family protein 1918626 13693374 O3M_09140 Escherichia coli O104:H4 str. 2009EL-2050 glycosyl transferase family protein YP_006769485.1 1917403 D 1134782 CDS YP_006769486.1 410481940 13693375 1918629..1920065 1 NC_018650.1 COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanyltransferase 1920065 cpsB 13693375 cpsB Escherichia coli O104:H4 str. 2009EL-2050 mannose-1-phosphate guanyltransferase YP_006769486.1 1918629 D 1134782 CDS YP_006769487.1 410481941 13693376 1920434..1921804 1 NC_018650.1 COG1109 Phosphomannomutase; phosphomannomutase 1921804 13693376 O3M_09150 Escherichia coli O104:H4 str. 2009EL-2050 phosphomannomutase YP_006769487.1 1920434 D 1134782 CDS YP_006769488.1 410481942 13693377 1921859..1923253 1 NC_018650.1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; UDP-glucose lipid carrier transferase 1923253 13693377 O3M_09155 Escherichia coli O104:H4 str. 2009EL-2050 UDP-glucose lipid carrier transferase YP_006769488.1 1921859 D 1134782 CDS YP_006769489.1 410481943 13693378 1923255..1924733 1 NC_018650.1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; colanic acid exporter 1924733 13693378 O3M_09160 Escherichia coli O104:H4 str. 2009EL-2050 colanic acid exporter YP_006769489.1 1923255 D 1134782 CDS YP_006769490.1 410481944 13693379 1925018..1926298 1 NC_018650.1 COG2327 Uncharacterized conserved protein; colanic acid biosynthesis protein 1926298 13693379 O3M_09165 Escherichia coli O104:H4 str. 2009EL-2050 colanic acid biosynthesis protein YP_006769490.1 1925018 D 1134782 CDS YP_006769491.1 410481945 13693380 1926295..1927515 1 NC_018650.1 COG0438 Glycosyltransferase; colanic acid biosynthesis glycosyltransferase WcaL 1927515 13693380 O3M_09170 Escherichia coli O104:H4 str. 2009EL-2050 colanic acid biosynthesis glycosyltransferase WcaL YP_006769491.1 1926295 D 1134782 CDS YP_006769492.1 410481946 13693381 1927526..1928920 1 NC_018650.1 colanic acid biosynthesis protein 1928920 wcaM 13693381 wcaM Escherichia coli O104:H4 str. 2009EL-2050 colanic acid biosynthesis protein YP_006769492.1 1927526 D 1134782 CDS YP_006769493.1 410481947 13693382 1929078..1930073 1 NC_018650.1 COG0451 Nucleoside-diphosphate-sugar epimerases; UDP-N-acetylglucosamine 4-epimerase 1930073 13693382 O3M_09180 Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylglucosamine 4-epimerase YP_006769493.1 1929078 D 1134782 CDS YP_006769494.1 410481948 13693383 1930316..1931209 1 NC_018650.1 COG1210 UDP-glucose pyrophosphorylase; GalU regulator GalF 1931209 13693383 O3M_09185 Escherichia coli O104:H4 str. 2009EL-2050 GalU regulator GalF YP_006769494.1 1930316 D 1134782 CDS YP_006769495.1 410481949 13693384 1931570..1932190 1 NC_018650.1 COG0110 Acetyltransferase (isoleucine patch superfamily); WckD 1932190 13693384 O3M_09190 Escherichia coli O104:H4 str. 2009EL-2050 WckD YP_006769495.1 1931570 D 1134782 CDS YP_006769496.1 410481950 13693385 1932195..1933235 1 NC_018650.1 COG2089 Sialic acid synthase; NnaB 1933235 13693385 O3M_09195 Escherichia coli O104:H4 str. 2009EL-2050 NnaB YP_006769496.1 1932195 D 1134782 CDS YP_006769497.1 410481951 13693386 1933241..1934506 1 NC_018650.1 COG1083 CMP-N-acetylneuraminic acid synthetase; N-acylneuraminate cytidylyltransferase 1934506 13693386 O3M_09200 Escherichia coli O104:H4 str. 2009EL-2050 N-acylneuraminate cytidylyltransferase YP_006769497.1 1933241 D 1134782 CDS YP_006769498.1 410481952 13693387 1934503..1935666 1 NC_018650.1 COG0381 UDP-N-acetylglucosamine 2-epimerase; NnaA 1935666 13693387 O3M_09205 Escherichia coli O104:H4 str. 2009EL-2050 NnaA YP_006769498.1 1934503 D 1134782 CDS YP_006769499.1 410481953 13693388 1935751..1936701 1 NC_018650.1 hypothetical protein 1936701 13693388 O3M_09210 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769499.1 1935751 D 1134782 CDS YP_006769500.1 410481954 13693389 1936698..1937810 1 NC_018650.1 hypothetical protein 1937810 13693389 O3M_09215 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769500.1 1936698 D 1134782 CDS YP_006769501.1 410481955 13693390 1937816..1939039 1 NC_018650.1 COG0438 Glycosyltransferase; WbwB 1939039 13693390 O3M_09220 Escherichia coli O104:H4 str. 2009EL-2050 WbwB YP_006769501.1 1937816 D 1134782 CDS YP_006769502.1 410481956 13693391 1939039..1940316 1 NC_018650.1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Wzx 1940316 13693391 O3M_09225 Escherichia coli O104:H4 str. 2009EL-2050 Wzx YP_006769502.1 1939039 D 1134782 CDS YP_006769503.1 410481957 13693392 1940341..1941147 1 NC_018650.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1941147 13693392 O3M_09230 Escherichia coli O104:H4 str. 2009EL-2050 glycosyl transferase family protein YP_006769503.1 1940341 D 1134782 CDS YP_006769504.1 410481958 13693393 1941268..1942674 1 NC_018650.1 COG0362 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase 1942674 13693393 O3M_09235 Escherichia coli O104:H4 str. 2009EL-2050 6-phosphogluconate dehydrogenase YP_006769504.1 1941268 D 1134782 CDS YP_006769505.1 410481959 13693394 1942922..1944088 1 NC_018650.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; UDP-glucose 6-dehydrogenase 1944088 13693394 O3M_09240 Escherichia coli O104:H4 str. 2009EL-2050 UDP-glucose 6-dehydrogenase YP_006769505.1 1942922 D 1134782 CDS YP_006769506.1 410481960 13693395 1944235..1945212 1 NC_018650.1 COG3765 Chain length determinant protein; chain length determinant protein WzzB 1945212 13693395 O3M_09245 Escherichia coli O104:H4 str. 2009EL-2050 chain length determinant protein WzzB YP_006769506.1 1944235 D 1134782 CDS YP_006769507.1 410481961 13693396 complement(1945310..1945921) 1 NC_018650.1 COG0139 Phosphoribosyl-AMP cyclohydrolase; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1945921 13693396 O3M_09250 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_006769507.1 1945310 R 1134782 CDS YP_006769508.1 410481962 13693397 complement(1945915..1946691) 1 NC_018650.1 COG0107 Imidazoleglycerol-phosphate synthase; imidazole glycerol phosphate synthase subunit HisF 1946691 13693397 O3M_09255 Escherichia coli O104:H4 str. 2009EL-2050 imidazole glycerol phosphate synthase subunit HisF YP_006769508.1 1945915 R 1134782 CDS YP_006769509.1 410481963 13693398 complement(1946673..1947410) 1 NC_018650.1 COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1947410 13693398 O3M_09260 Escherichia coli O104:H4 str. 2009EL-2050 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_006769509.1 1946673 R 1134782 CDS YP_006769510.1 410481964 13693399 complement(1947410..1948000) 1 NC_018650.1 COG0118 Glutamine amidotransferase; imidazole glycerol phosphate synthase subunit HisH 1948000 hisH 13693399 hisH Escherichia coli O104:H4 str. 2009EL-2050 imidazole glycerol phosphate synthase subunit HisH YP_006769510.1 1947410 R 1134782 CDS YP_006769511.1 410481965 13693400 complement(1948000..1949067) 1 NC_018650.1 COG0241 Histidinol phosphatase and related phosphatases; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1949067 13693400 O3M_09270 Escherichia coli O104:H4 str. 2009EL-2050 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_006769511.1 1948000 R 1134782 CDS YP_006769512.1 410481966 13693401 complement(1949067..1950137) 1 NC_018650.1 COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; histidinol-phosphate aminotransferase 1950137 13693401 O3M_09275 Escherichia coli O104:H4 str. 2009EL-2050 histidinol-phosphate aminotransferase YP_006769512.1 1949067 R 1134782 CDS YP_006769513.1 410481967 13693402 complement(1950134..1951438) 1 NC_018650.1 COG0141 Histidinol dehydrogenase; bifunctional histidinal dehydrogenase/ histidinol dehydrogenase 1951438 hisD 13693402 hisD Escherichia coli O104:H4 str. 2009EL-2050 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase YP_006769513.1 1950134 R 1134782 CDS YP_006769514.1 410481968 13693403 complement(1951444..1952343) 1 NC_018650.1 COG0040 ATP phosphoribosyltransferase; ATP phosphoribosyltransferase 1952343 hisG 13693403 hisG Escherichia coli O104:H4 str. 2009EL-2050 ATP phosphoribosyltransferase YP_006769514.1 1951444 R 1134782 CDS YP_006769515.1 410481969 13693404 1952823..1953074 1 NC_018650.1 COG2161 Antitoxin of toxin-antitoxin stability system; antitoxin YefM 1953074 13693404 O3M_09290 Escherichia coli O104:H4 str. 2009EL-2050 antitoxin YefM YP_006769515.1 1952823 D 1134782 CDS YP_006769516.1 410481970 13693405 1953071..1953325 1 NC_018650.1 COG4115 Uncharacterized protein conserved in bacteria; Toxin yoeB 1953325 13693405 O3M_09295 Escherichia coli O104:H4 str. 2009EL-2050 Toxin yoeB YP_006769516.1 1953071 D 1134782 CDS YP_006769517.1 410481971 13693406 1953408..1954232 1 NC_018650.1 COG0451 Nucleoside-diphosphate-sugar epimerases; epimerase, with NAD(P)-binding Rossmann-fold domain 1954232 13693406 O3M_09300 Escherichia coli O104:H4 str. 2009EL-2050 epimerase, with NAD(P)-binding Rossmann-fold domain YP_006769517.1 1953408 D 1134782 CDS YP_006769518.1 410481972 13693407 1954278..1955207 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 1955207 13693407 O3M_09305 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006769518.1 1954278 D 1134782 CDS YP_006769519.1 410481973 13693408 1955474..1956832 1 NC_018650.1 COG0531 Amino acid transporters; amino acid permease 1956832 13693408 O3M_09310 Escherichia coli O104:H4 str. 2009EL-2050 amino acid permease YP_006769519.1 1955474 D 1134782 CDS YP_006769520.1 410481974 13693409 1957011..1958069 1 NC_018650.1 COG2391 Predicted transporter component; hypothetical protein 1958069 13693409 O3M_09315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769520.1 1957011 D 1134782 CDS YP_006769521.1 410481975 13693410 1958083..1958310 1 NC_018650.1 COG0425 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 1958310 13693410 O3M_09320 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769521.1 1958083 D 1134782 CDS YP_006769522.1 410481976 13693411 complement(1958353..1959777) 1 NC_018650.1 COG2925 Exonuclease I; exonuclease I 1959777 sbcB 13693411 sbcB Escherichia coli O104:H4 str. 2009EL-2050 exonuclease I YP_006769522.1 1958353 R 1134782 CDS YP_006769523.1 410481977 13693412 1959989..1961155 1 NC_018650.1 COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 1961155 dacD 13693412 dacD Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-D-alanine carboxypeptidase YP_006769523.1 1959989 D 1134782 CDS YP_006769524.1 410481978 13693413 1961274..1961747 1 NC_018650.1 COG3449 DNA gyrase inhibitor; DNA gyrase inhibitor 1961747 13693413 O3M_09335 Escherichia coli O104:H4 str. 2009EL-2050 DNA gyrase inhibitor YP_006769524.1 1961274 D 1134782 CDS YP_006769525.1 410481979 13693414 1961945..1962625 1 NC_018650.1 COG1289 Predicted membrane protein; inner membrane protein YeeA 1962625 13693414 O3M_09340 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YeeA YP_006769525.1 1961945 D 1134782 CDS YP_006769526.1 410481980 13693415 1962689..1963669 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 1963669 13693415 O3M_09345 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006769526.1 1962689 D 1134782 CDS YP_006769527.1 410481981 13693416 1963860..1964282 1 NC_018650.1 inner membrane protein YeeA 1964282 13693416 O3M_09350 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YeeA YP_006769527.1 1963860 D 1134782 CDS YP_006769528.1 410481982 13693417 1964454..1964783 1 NC_018650.1 COG2926 Uncharacterized protein conserved in bacteria; hypothetical protein 1964783 13693417 O3M_09355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769528.1 1964454 D 1134782 CDS YP_006769529.1 410481983 13693418 complement(1964884..1965108) 1 NC_018650.1 COG4917 Ethanolamine utilization protein; hypothetical protein 1965108 13693418 O3M_09360 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769529.1 1964884 R 1134782 CDS YP_006769530.1 410481984 13693419 complement(1965555..1965668) 1 NC_018650.1 hypothetical protein 1965668 13693419 O3M_09365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769530.1 1965555 R 1134782 CDS YP_006769531.1 410481985 13693420 complement(1965681..1965875) 1 NC_018650.1 hypothetical protein 1965875 13693420 O3M_09370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769531.1 1965681 R 1134782 CDS YP_006769532.1 410481986 13693421 complement(1965982..1966245) 1 NC_018650.1 hypothetical protein 1966245 13693421 O3M_09375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769532.1 1965982 R 1134782 CDS YP_006769533.1 410481987 13693422 complement(1966334..1966702) 1 NC_018650.1 hypothetical protein 1966702 13693422 O3M_09380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769533.1 1966334 R 1134782 CDS YP_006769534.1 410481988 13693423 complement(1966776..1966997) 1 NC_018650.1 hypothetical protein 1966997 13693423 O3M_09385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769534.1 1966776 R 1134782 CDS YP_006769535.1 410481989 13693424 complement(1967060..1967536) 1 NC_018650.1 COG2003 DNA repair proteins; DNA repair protein 1967536 13693424 O3M_09390 Escherichia coli O104:H4 str. 2009EL-2050 DNA repair protein YP_006769535.1 1967060 R 1134782 CDS YP_006769536.1 410481990 13693425 complement(1967552..1968031) 1 NC_018650.1 antirestriction protein 1968031 13693425 O3M_09395 Escherichia coli O104:H4 str. 2009EL-2050 antirestriction protein YP_006769536.1 1967552 R 1134782 CDS YP_006769537.1 410481991 13693426 complement(1968113..1968934) 1 NC_018650.1 hypothetical protein 1968934 13693426 O3M_09400 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769537.1 1968113 R 1134782 CDS YP_006769538.1 410481992 13693427 complement(1969155..1969565) 1 NC_018650.1 hypothetical protein 1969565 13693427 O3M_09405 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769538.1 1969155 R 1134782 CDS YP_006769539.1 410481993 13693428 complement(1969581..1970264) 1 NC_018650.1 hypothetical protein 1970264 13693428 O3M_09410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769539.1 1969581 R 1134782 CDS YP_006769540.1 410481994 13693429 complement(1970400..1971470) 1 NC_018650.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein 1971470 13693429 O3M_09415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769540.1 1970400 R 1134782 CDS YP_006769541.1 410481995 13693430 complement(1971467..1972372) 1 NC_018650.1 hypothetical protein 1972372 13693430 O3M_09420 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769541.1 1971467 R 1134782 CDS YP_006769542.1 410481996 13693431 complement(1972369..1974765) 1 NC_018650.1 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 1974765 13693431 O3M_09425 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769542.1 1972369 R 1134782 CDS YP_006769543.1 410481997 13693432 complement(1975938..1977089) 1 NC_018650.1 hypothetical protein 1977089 13693432 O3M_09440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769543.1 1975938 R 1134782 CDS YP_006769544.1 410481998 13693433 complement(1978293..1978568) 1 NC_018650.1 COG4584 Transposase and inactivated derivatives; transposase subunit 1978568 13693433 O3M_09445 Escherichia coli O104:H4 str. 2009EL-2050 transposase subunit YP_006769544.1 1978293 R 1134782 CDS YP_006769545.1 410481999 13693434 complement(1978474..1978770) 1 NC_018650.1 hypothetical protein 1978770 13693434 O3M_09450 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769545.1 1978474 R 1134782 CDS YP_006769546.1 410482000 13693435 1978657..1979040 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 1979040 13693435 O3M_09455 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769546.1 1978657 D 1134782 CDS YP_006769547.1 410482001 13693436 1979037..1979384 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF 2, IS66 family protein 1979384 13693436 O3M_09460 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF 2, IS66 family protein YP_006769547.1 1979037 D 1134782 CDS YP_006769548.1 410482002 13693437 1979434..1980969 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF 1, IS66 family protein 1980969 13693437 O3M_09465 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF 1, IS66 family protein YP_006769548.1 1979434 D 1134782 CDS YP_006769549.1 410482003 13693438 complement(1981928..1982536) 1 NC_018650.1 hypothetical protein 1982536 13693438 O3M_09470 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769549.1 1981928 R 1134782 CDS YP_006769550.1 410482004 13693439 complement(1982624..1982830) 1 NC_018650.1 COG3311 Predicted transcriptional regulator; InterPro motifs Prophage CP4-57 regulatory protein (AlpA) 1982830 13693439 O3M_09475 Escherichia coli O104:H4 str. 2009EL-2050 InterPro motifs Prophage CP4-57 regulatory protein (AlpA) YP_006769550.1 1982624 R 1134782 CDS YP_006769551.1 410482005 13693440 1982937..1983239 1 NC_018650.1 hypothetical protein 1983239 13693440 O3M_09480 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769551.1 1982937 D 1134782 CDS YP_006769552.1 410482006 13693441 complement(1983957..1984157) 1 NC_018650.1 hypothetical protein 1984157 13693441 O3M_09485 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769552.1 1983957 R 1134782 CDS YP_006769553.1 410482007 13693442 1984357..1984926 1 NC_018650.1 hypothetical protein 1984926 13693442 O3M_09490 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769553.1 1984357 D 1134782 CDS YP_006769554.1 410482008 13693443 1985180..1985587 1 NC_018650.1 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 1985587 13693443 O3M_09495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769554.1 1985180 D 1134782 CDS YP_006769555.1 410482009 13693444 1985575..1985985 1 NC_018650.1 hypothetical protein 1985985 13693444 O3M_09500 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769555.1 1985575 D 1134782 CDS YP_006769556.1 410482010 13693445 complement(1986408..1986659) 1 NC_018650.1 hypothetical protein 1986659 13693445 O3M_09505 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769556.1 1986408 R 1134782 CDS YP_006769557.1 410482011 13693446 1986791..1987648 1 NC_018650.1 COG3464 Transposase and inactivated derivatives; transposase, ISL3 family protein 1987648 13693446 O3M_09510 Escherichia coli O104:H4 str. 2009EL-2050 transposase, ISL3 family protein YP_006769557.1 1986791 D 1134782 CDS YP_006769558.1 410482012 13693447 1987727..1987888 1 NC_018650.1 COG3464 Transposase and inactivated derivatives; transposase (part) 1987888 13693447 O3M_09515 Escherichia coli O104:H4 str. 2009EL-2050 transposase (part) YP_006769558.1 1987727 D 1134782 CDS YP_006769559.1 410482013 13693448 1987989..1988156 1 NC_018650.1 COG0405 Gamma-glutamyltransferase; hypothetical protein 1988156 13693448 O3M_09520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769559.1 1987989 D 1134782 CDS YP_006769560.1 410482014 13693449 1988147..1988260 1 NC_018650.1 hypothetical protein 1988260 13693449 O3M_09525 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769560.1 1988147 D 1134782 CDS YP_006769561.1 410482015 13693450 complement(1988300..1989334) 1 NC_018650.1 COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold; phosphotriesterase-related protein 1989334 13693450 O3M_09530 Escherichia coli O104:H4 str. 2009EL-2050 phosphotriesterase-related protein YP_006769561.1 1988300 R 1134782 CDS YP_006769562.1 410482016 13693451 complement(1990359..1991117) 1 NC_018650.1 COG5426 Uncharacterized membrane protein; hypothetical protein 1991117 13693451 O3M_09545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769562.1 1990359 R 1134782 CDS YP_006769563.1 410482017 13693452 complement(1991131..1992345) 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; carbohydrate kinase 1992345 13693452 O3M_09550 Escherichia coli O104:H4 str. 2009EL-2050 carbohydrate kinase YP_006769563.1 1991131 R 1134782 CDS YP_006769564.1 410482018 13693453 complement(1992541..1992657) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 1992657 13693453 O3M_09555 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769564.1 1992541 R 1134782 CDS YP_006769565.1 410482019 13693454 complement(1992597..1993088) 1 NC_018650.1 hypothetical protein 1993088 13693454 O3M_09560 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769565.1 1992597 R 1134782 CDS YP_006769566.1 410482020 13693455 1993779..1993943 1 NC_018650.1 hypothetical protein 1993943 13693455 O3M_09565 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769566.1 1993779 D 1134782 CDS YP_006769567.1 410482021 13693456 1994408..1994953 1 NC_018650.1 COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1994953 cobU 13693456 cobU Escherichia coli O104:H4 str. 2009EL-2050 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_006769567.1 1994408 D 1134782 CDS YP_006769568.1 410482022 13693457 1994950..1995693 1 NC_018650.1 COG0368 Cobalamin-5-phosphate synthase; cobalamin synthase 1995693 cobS 13693457 cobS Escherichia coli O104:H4 str. 2009EL-2050 cobalamin synthase YP_006769568.1 1994950 D 1134782 CDS YP_006769569.1 410482023 13693458 1995705..1996784 1 NC_018650.1 COG2038 NaMN:DMB phosphoribosyltransferase; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1996784 cobT 13693458 cobT Escherichia coli O104:H4 str. 2009EL-2050 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_006769569.1 1995705 D 1134782 CDS YP_006769570.1 410482024 13693459 1996849..1997781 1 NC_018650.1 COG1376 Uncharacterized protein conserved in bacteria; L,D-transpeptidase 1997781 13693459 O3M_09585 Escherichia coli O104:H4 str. 2009EL-2050 L,D-transpeptidase YP_006769570.1 1996849 D 1134782 CDS YP_006769571.1 410482025 13693461 1998239..1999156 1 NC_018650.1 COG0583 Transcriptional regulator; nitrogen assimilation transcriptional regulator 1999156 13693461 O3M_09590 Escherichia coli O104:H4 str. 2009EL-2050 nitrogen assimilation transcriptional regulator YP_006769571.1 1998239 D 1134782 CDS YP_006769572.1 410482026 13693462 1999258..2000208 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional regulator Cbl 2000208 cbl 13693462 cbl Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator Cbl YP_006769572.1 1999258 D 1134782 CDS YP_006769573.1 410482027 13693464 2000329..2001969 1 NC_018650.1 COG0534 Na+-driven multidrug efflux pump; MATE family multidrug exporter 2001969 13693464 O3M_09600 Escherichia coli O104:H4 str. 2009EL-2050 MATE family multidrug exporter YP_006769573.1 2000329 D 1134782 CDS YP_006769574.1 410482028 13693466 complement(2002597..2003313) 1 NC_018650.1 COG0217 Uncharacterized conserved protein; hypothetical protein 2003313 13693466 O3M_09605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769574.1 2002597 R 1134782 CDS YP_006769575.1 410482029 13693467 complement(2003656..2005110) 1 NC_018650.1 COG0775 Nucleoside phosphorylase; AMP nucleosidase 2005110 13693467 O3M_09610 Escherichia coli O104:H4 str. 2009EL-2050 AMP nucleosidase YP_006769575.1 2003656 R 1134782 CDS YP_006769576.1 410482030 13693468 complement(2005212..2006528) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; shikimate transporter 2006528 13693468 O3M_09615 Escherichia coli O104:H4 str. 2009EL-2050 shikimate transporter YP_006769576.1 2005212 R 1134782 CDS YP_006769577.1 410482031 13693469 2006843..2007895 1 NC_018650.1 COG0859 ADP-heptose:LPS heptosyltransferase; hypothetical protein 2007895 13693469 O3M_09620 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769577.1 2006843 D 1134782 CDS YP_006769578.1 410482032 13693470 complement(2010017..2010157) 1 NC_018650.1 hypothetical protein 2010157 13693470 O3M_09635 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769578.1 2010017 R 1134782 CDS YP_006769579.1 410482033 13693471 complement(2010114..2010536) 1 NC_018650.1 hypothetical protein 2010536 13693471 O3M_09640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769579.1 2010114 R 1134782 CDS YP_006769580.1 410482034 13693472 complement(2011514..2013535) 1 NC_018650.1 COG1629 Outer membrane receptor proteins, mostly Fe transport; Yersiniabactin/pesticin outer membrane receptor (IRPC) 2013535 13693472 O3M_09645 Escherichia coli O104:H4 str. 2009EL-2050 Yersiniabactin/pesticin outer membrane receptor (IRPC) YP_006769580.1 2011514 R 1134782 CDS YP_006769581.1 410482035 13693473 complement(2013666..2015243) 1 NC_018650.1 COG1021 Peptide arylation enzymes; salicyl-AMP ligase YbtE 2015243 13693473 O3M_09650 Escherichia coli O104:H4 str. 2009EL-2050 salicyl-AMP ligase YbtE YP_006769581.1 2013666 R 1134782 CDS YP_006769582.1 410482036 13693474 complement(2015247..2016050) 1 NC_018650.1 COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis; siderophore biosynthetic protein 2016050 13693474 O3M_09655 Escherichia coli O104:H4 str. 2009EL-2050 siderophore biosynthetic protein YP_006769582.1 2015247 R 1134782 CDS YP_006769583.1 410482037 13693475 complement(2016047..2017147) 1 NC_018650.1 COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis; Thiazolinyl-S-HMWP1 reductase YbtU 2017147 13693475 O3M_09660 Escherichia coli O104:H4 str. 2009EL-2050 Thiazolinyl-S-HMWP1 reductase YbtU YP_006769583.1 2016047 R 1134782 CDS YP_006769584.1 410482038 13693476 complement(2017144..2026635) 1 NC_018650.1 COG3321 Polyketide synthase modules and related proteins; High-molecular-weight nonribosomal peptide/polyketide synthetase 1 (HMWP1) 2026635 13693476 O3M_09665 Escherichia coli O104:H4 str. 2009EL-2050 High-molecular-weight nonribosomal peptide/polyketide synthetase 1 (HMWP1) YP_006769584.1 2017144 R 1134782 CDS YP_006769585.1 410482039 13693477 complement(2026723..2032830) 1 NC_018650.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; High-molecular-weight nonribosomal peptide/polyketide synthetase 2 (HMWP2) 2032830 13693477 O3M_09670 Escherichia coli O104:H4 str. 2009EL-2050 High-molecular-weight nonribosomal peptide/polyketide synthetase 2 (HMWP2) YP_006769585.1 2026723 R 1134782 CDS YP_006769586.1 410482040 13693478 complement(2033021..2033980) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 2033980 13693478 O3M_09675 Escherichia coli O104:H4 str. 2009EL-2050 AraC family transcriptional regulator YP_006769586.1 2033021 R 1134782 CDS YP_006769587.1 410482041 13693479 2034147..2035949 1 NC_018650.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtP 2035949 13693479 O3M_09680 Escherichia coli O104:H4 str. 2009EL-2050 yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtP YP_006769587.1 2034147 D 1134782 CDS YP_006769588.1 410482042 13693480 2035936..2037738 1 NC_018650.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtQ 2037738 13693480 O3M_09685 Escherichia coli O104:H4 str. 2009EL-2050 yersiniabactin-iron ABC transporter permease/ATP-binding protein YbtQ YP_006769588.1 2035936 D 1134782 CDS YP_006769589.1 410482043 13693481 2037731..2039011 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; yersiniabactin-iron transporter permease YbtX 2039011 13693481 O3M_09690 Escherichia coli O104:H4 str. 2009EL-2050 yersiniabactin-iron transporter permease YbtX YP_006769589.1 2037731 D 1134782 CDS YP_006769590.1 410482044 13693482 2039039..2040343 1 NC_018650.1 COG0147 Anthranilate/para-aminobenzoate synthases component I; salicylate synthase Irp9 2040343 13693482 O3M_09695 Escherichia coli O104:H4 str. 2009EL-2050 salicylate synthase Irp9 YP_006769590.1 2039039 D 1134782 CDS YP_006769591.1 410482045 13693483 complement(2040537..2041799) 1 NC_018650.1 COG0582 Integrase; integrase 2041799 13693483 O3M_09700 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006769591.1 2040537 R 1134782 CDS YP_006769592.1 410482046 13693485 complement(2042137..2042934) 1 NC_018650.1 COG3228 Uncharacterized protein conserved in bacteria; DgsA anti-repressor MtfA 2042934 13693485 O3M_09705 Escherichia coli O104:H4 str. 2009EL-2050 DgsA anti-repressor MtfA YP_006769592.1 2042137 R 1134782 CDS YP_006769593.1 410482047 13693487 complement(2043787..2044437) 1 NC_018650.1 COG3443 Predicted periplasmic or secreted protein; zinc/cadmium-binding protein 2044437 13693487 O3M_09710 Escherichia coli O104:H4 str. 2009EL-2050 zinc/cadmium-binding protein YP_006769593.1 2043787 R 1134782 CDS YP_006769594.1 410482048 13693488 complement(2044694..2045329) 1 NC_018650.1 COG2717 Predicted membrane protein; sulfite oxidase subunit YedZ 2045329 13693488 O3M_09715 Escherichia coli O104:H4 str. 2009EL-2050 sulfite oxidase subunit YedZ YP_006769594.1 2044694 R 1134782 CDS YP_006769595.1 410482049 13693489 complement(2045330..2046334) 1 NC_018650.1 COG2041 Sulfite oxidase and related enzymes; TMAO/DMSO reductase 2046334 13693489 O3M_09720 Escherichia coli O104:H4 str. 2009EL-2050 TMAO/DMSO reductase YP_006769595.1 2045330 R 1134782 CDS YP_006769596.1 410482050 13693490 complement(2046443..2046856) 1 NC_018650.1 COG2351 Transthyretin-like protein; hydroxyisourate hydrolase 2046856 13693490 O3M_09725 Escherichia coli O104:H4 str. 2009EL-2050 hydroxyisourate hydrolase YP_006769596.1 2046443 R 1134782 CDS YP_006769597.1 410482051 13693491 2046989..2047660 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulatory protein YedW 2047660 13693491 O3M_09730 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulatory protein YedW YP_006769597.1 2046989 D 1134782 CDS YP_006769598.1 410482052 13693492 2047660..2049018 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensory kinase in two-component regulatory system with YedW 2049018 13693492 O3M_09735 Escherichia coli O104:H4 str. 2009EL-2050 sensory kinase in two-component regulatory system with YedW YP_006769598.1 2047660 D 1134782 CDS YP_006769599.1 410482053 13693493 complement(2049116..2049967) 1 NC_018650.1 COG0693 Putative intracellular protease/amidase; chaperone protein HchA 2049967 13693493 O3M_09740 Escherichia coli O104:H4 str. 2009EL-2050 chaperone protein HchA YP_006769599.1 2049116 R 1134782 CDS YP_006769600.1 410482054 13693494 2050053..2050328 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA 2050328 13693494 O3M_09745 Escherichia coli O104:H4 str. 2009EL-2050 IS1 repressor protein InsA YP_006769600.1 2050053 D 1134782 CDS YP_006769601.1 410482055 13693495 2050247..2050750 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 2050750 13693495 O3M_09750 Escherichia coli O104:H4 str. 2009EL-2050 IS1 transposase InsAB' YP_006769601.1 2050247 D 1134782 CDS YP_006769602.1 410482056 13693496 complement(2051256..2051969) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; hypothetical protein 2051969 13693496 O3M_09755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769602.1 2051256 R 1134782 CDS YP_006769603.1 410482057 13693497 2052214..2053365 1 NC_018650.1 COG2826 Transposase and inactivated derivatives, IS30 family; IS30 transposase: KpLE2 phage-like element 2053365 13693497 O3M_09760 Escherichia coli O104:H4 str. 2009EL-2050 IS30 transposase: KpLE2 phage-like element YP_006769603.1 2052214 D 1134782 CDS YP_006769604.1 410482058 13693498 complement(2053285..2053635) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 2053635 13693498 O3M_09765 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769604.1 2053285 R 1134782 CDS YP_006769605.1 410482059 13693499 2055312..2055677 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; inner membrane protein 2055677 13693499 O3M_09780 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769605.1 2055312 D 1134782 CDS YP_006769606.1 410482060 13693500 2055717..2056412 1 NC_018650.1 COG1418 Predicted HD superfamily hydrolase; hydrolase 2056412 13693500 O3M_09785 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006769606.1 2055717 D 1134782 CDS YP_006769607.1 410482061 13693501 2056479..2057897 1 NC_018650.1 COG0270 Site-specific DNA methylase; DNA cytosine methylase 2057897 13693501 O3M_09790 Escherichia coli O104:H4 str. 2009EL-2050 DNA cytosine methylase YP_006769607.1 2056479 D 1134782 CDS YP_006769608.1 410482062 13693502 2057878..2058348 1 NC_018650.1 COG3727 DNA G:T-mismatch repair endonuclease; very short patch repair protein 2058348 13693502 O3M_09795 Escherichia coli O104:H4 str. 2009EL-2050 very short patch repair protein YP_006769608.1 2057878 D 1134782 CDS YP_006769609.1 410482063 13693503 complement(2058337..2059257) 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; DMT superfamily transporter inner membrane protein 2059257 13693503 O3M_09800 Escherichia coli O104:H4 str. 2009EL-2050 DMT superfamily transporter inner membrane protein YP_006769609.1 2058337 R 1134782 CDS YP_006769610.1 410482064 13693504 2059430..2060347 1 NC_018650.1 COG2354 Uncharacterized protein conserved in bacteria; hypothetical protein 2060347 13693504 O3M_09805 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769610.1 2059430 D 1134782 CDS YP_006769611.1 410482065 13693505 2060426..2060608 1 NC_018650.1 COG5475 Uncharacterized small protein; hypothetical protein 2060608 13693505 O3M_09810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769611.1 2060426 D 1134782 CDS YP_006769612.1 410482066 13693506 2060779..2061714 1 NC_018650.1 diguanylate cyclase 2061714 13693506 O3M_09815 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006769612.1 2060779 D 1134782 CDS YP_006769613.1 410482067 13693507 2061718..2062473 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 2062473 13693507 O3M_09820 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006769613.1 2061718 D 1134782 CDS YP_006769614.1 410482068 13693508 complement(2062470..2063285) 1 NC_018650.1 COG3769 Predicted hydrolase (HAD superfamily); mannosyl-3-phosphoglycerate phosphatase 2063285 13693508 O3M_09825 Escherichia coli O104:H4 str. 2009EL-2050 mannosyl-3-phosphoglycerate phosphatase YP_006769614.1 2062470 R 1134782 CDS YP_006769615.1 410482069 13693509 complement(2063584..2063811) 1 NC_018650.1 hypothetical protein 2063811 13693509 O3M_09830 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769615.1 2063584 R 1134782 CDS YP_006769616.1 410482070 13693510 2063974..2064162 1 NC_018650.1 hypothetical protein 2064162 13693510 O3M_09835 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769616.1 2063974 D 1134782 CDS YP_006769617.1 410482071 13693511 complement(2064206..2064829) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; colanic acid capsular biosynthesis activation protein A 2064829 rcsA 13693511 rcsA Escherichia coli O104:H4 str. 2009EL-2050 colanic acid capsular biosynthesis activation protein A YP_006769617.1 2064206 R 1134782 CDS YP_006769618.1 410482072 13693512 complement(2065119..2065904) 1 NC_018650.1 COG1684 Flagellar biosynthesis pathway, component FliR; flagellar biosynthesis protein FliR 2065904 fliR 13693512 fliR Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis protein FliR YP_006769618.1 2065119 R 1134782 CDS YP_006769619.1 410482073 13693513 complement(2065913..2066182) 1 NC_018650.1 COG1987 Flagellar biosynthesis pathway, component FliQ; flagellar biosynthesis protein FliQ 2066182 fliQ 13693513 fliQ Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis protein FliQ YP_006769619.1 2065913 R 1134782 CDS YP_006769620.1 410482074 13693514 complement(2066192..2066929) 1 NC_018650.1 COG1338 Flagellar biosynthesis pathway, component FliP; flagellar biosynthesis protein FliP 2066929 fliP 13693514 fliP Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis protein FliP YP_006769620.1 2066192 R 1134782 CDS YP_006769621.1 410482075 13693515 complement(2066929..2067294) 1 NC_018650.1 COG3190 Flagellar biogenesis protein; flagellar biosynthesis protein FliO 2067294 13693515 O3M_09860 Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis protein FliO YP_006769621.1 2066929 R 1134782 CDS YP_006769622.1 410482076 13693516 complement(2067297..2067710) 1 NC_018650.1 COG1886 Flagellar motor switch/type III secretory pathway protein; flagellar motor switch protein FliN 2067710 fliN 13693516 fliN Escherichia coli O104:H4 str. 2009EL-2050 flagellar motor switch protein FliN YP_006769622.1 2067297 R 1134782 CDS YP_006769623.1 410482077 13693517 complement(2067707..2068711) 1 NC_018650.1 COG1868 Flagellar motor switch protein; flagellar motor switch protein FliM 2068711 fliM 13693517 fliM Escherichia coli O104:H4 str. 2009EL-2050 flagellar motor switch protein FliM YP_006769623.1 2067707 R 1134782 CDS YP_006769624.1 410482078 13693518 complement(2068716..2069180) 1 NC_018650.1 COG1580 Flagellar basal body-associated protein; flagellar basal body-associated protein FliL 2069180 fliL 13693518 fliL Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body-associated protein FliL YP_006769624.1 2068716 R 1134782 CDS YP_006769625.1 410482079 13693519 complement(2069285..2070412) 1 NC_018650.1 COG3144 Flagellar hook-length control protein; flagellar hook-length control protein 2070412 13693519 O3M_09880 Escherichia coli O104:H4 str. 2009EL-2050 flagellar hook-length control protein YP_006769625.1 2069285 R 1134782 CDS YP_006769626.1 410482080 13693520 complement(2070409..2070852) 1 NC_018650.1 COG2882 Flagellar biosynthesis chaperone; flagellar biosynthesis chaperone 2070852 fliJ 13693520 fliJ Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis chaperone YP_006769626.1 2070409 R 1134782 CDS YP_006769627.1 410482081 13693521 complement(2070871..2072244) 1 NC_018650.1 COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; flagellum-specific ATP synthase 2072244 fliI 13693521 fliI Escherichia coli O104:H4 str. 2009EL-2050 flagellum-specific ATP synthase YP_006769627.1 2070871 R 1134782 CDS YP_006769628.1 410482082 13693522 complement(2072244..2072930) 1 NC_018650.1 COG1317 Flagellar biosynthesis/type III secretory pathway protein; flagellar assembly protein H 2072930 fliH 13693522 fliH Escherichia coli O104:H4 str. 2009EL-2050 flagellar assembly protein H YP_006769628.1 2072244 R 1134782 CDS YP_006769629.1 410482083 13693523 complement(2072923..2073918) 1 NC_018650.1 COG1536 Flagellar motor switch protein; flagellar motor switch protein G 2073918 fliG 13693523 fliG Escherichia coli O104:H4 str. 2009EL-2050 flagellar motor switch protein G YP_006769629.1 2072923 R 1134782 CDS YP_006769630.1 410482084 13693524 complement(2073911..2075569) 1 NC_018650.1 COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; flagellar MS-ring protein 2075569 fliF 13693524 fliF Escherichia coli O104:H4 str. 2009EL-2050 flagellar MS-ring protein YP_006769630.1 2073911 R 1134782 CDS YP_006769631.1 410482085 13693525 2075784..2076098 1 NC_018650.1 COG1677 Flagellar hook-basal body protein; flagellar hook-basal body protein FliE 2076098 fliE 13693525 fliE Escherichia coli O104:H4 str. 2009EL-2050 flagellar hook-basal body protein FliE YP_006769631.1 2075784 D 1134782 CDS YP_006769632.1 410482086 13693526 2076442..2076774 1 NC_018650.1 COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein 2076774 emrE 13693526 emrE Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux protein YP_006769632.1 2076442 D 1134782 CDS YP_006769633.1 410482087 13693527 2076943..2077494 1 NC_018650.1 COG1881 Phospholipid-binding protein; kinase inhibitor 2077494 13693527 O3M_09920 Escherichia coli O104:H4 str. 2009EL-2050 kinase inhibitor YP_006769633.1 2076943 D 1134782 CDS YP_006769634.1 410482088 13693528 2077504..2078301 1 NC_018650.1 DLP12 prophage; COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 2078301 13693528 O3M_09925 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006769634.1 2077504 D 1134782 CDS YP_006769635.1 410482089 13693529 complement(2078458..2078982) 1 NC_018650.1 COG1943 Transposase and inactivated derivatives; IS609 family protein; transposase ORF A, IS609 family protein 2078982 13693529 O3M_09930 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS609 family protein YP_006769635.1 2078458 R 1134782 CDS YP_006769636.1 410482090 13693530 complement(2079216..2079713) 1 NC_018650.1 COG2135 Uncharacterized conserved protein; hypothetical protein 2079713 13693530 O3M_09935 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769636.1 2079216 R 1134782 CDS YP_006769637.1 410482091 13693531 complement(2079822..2080055) 1 NC_018650.1 COG0425 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 2080055 13693531 O3M_09940 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769637.1 2079822 R 1134782 CDS YP_006769638.1 410482092 13693532 complement(2080052..2081257) 1 NC_018650.1 COG2391 Predicted transporter component; inner membrane protein 2081257 13693532 O3M_09945 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769638.1 2080052 R 1134782 CDS YP_006769639.1 410482093 13693533 2081444..2081857 1 NC_018650.1 lipoprotein 2081857 13693533 O3M_09950 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006769639.1 2081444 D 1134782 CDS YP_006769640.1 410482094 13693534 complement(2081891..2083378) 1 NC_018650.1 COG0366 Glycosidases; alpha-amylase 2083378 13693534 O3M_09955 Escherichia coli O104:H4 str. 2009EL-2050 alpha-amylase YP_006769640.1 2081891 R 1134782 CDS YP_006769641.1 410482095 13693535 complement(2083456..2083821) 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; flagellar biosynthesis protein FliT 2083821 13693535 O3M_09960 Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis protein FliT YP_006769641.1 2083456 R 1134782 CDS YP_006769642.1 410482096 13693536 complement(2083821..2084231) 1 NC_018650.1 COG1516 Flagellin-specific chaperone FliS; flagellar protein FliS 2084231 fliS 13693536 fliS Escherichia coli O104:H4 str. 2009EL-2050 flagellar protein FliS YP_006769642.1 2083821 R 1134782 CDS YP_006769643.1 410482097 13693537 complement(2084247..2085662) 1 NC_018650.1 COG1345 Flagellar capping protein; flagellar capping protein 2085662 fliD 13693537 fliD Escherichia coli O104:H4 str. 2009EL-2050 flagellar capping protein YP_006769643.1 2084247 R 1134782 CDS YP_006769644.1 410482098 13693538 2085910..2086959 1 NC_018650.1 COG1344 Flagellin and related hook-associated proteins; Flagellin 2086959 13693538 O3M_09975 Escherichia coli O104:H4 str. 2009EL-2050 Flagellin YP_006769644.1 2085910 D 1134782 CDS YP_006769645.1 410482099 13693539 2087123..2087842 1 NC_018650.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; flagellar biosynthesis sigma factor 2087842 fliA 13693539 fliA Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis sigma factor YP_006769645.1 2087123 D 1134782 CDS YP_006769646.1 410482100 13693540 2087888..2088439 1 NC_018650.1 flagella biosynthesis protein FliZ 2088439 13693540 O3M_09985 Escherichia coli O104:H4 str. 2009EL-2050 flagella biosynthesis protein FliZ YP_006769646.1 2087888 D 1134782 CDS YP_006769647.1 410482101 13693541 2088527..2089327 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; cystine transporter subunit 2089327 13693541 O3M_09990 Escherichia coli O104:H4 str. 2009EL-2050 cystine transporter subunit YP_006769647.1 2088527 D 1134782 CDS YP_006769648.1 410482102 13693542 2089432..2090418 1 NC_018650.1 COG2515 1-aminocyclopropane-1-carboxylate deaminase; D-cysteine desulfhydrase 2090418 13693542 O3M_09995 Escherichia coli O104:H4 str. 2009EL-2050 D-cysteine desulfhydrase YP_006769648.1 2089432 D 1134782 CDS YP_006769649.1 410482103 13693543 2090433..2091101 1 NC_018650.1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 2091101 13693543 O3M_10000 Escherichia coli O104:H4 str. 2009EL-2050 amino acid ABC transporter permease YP_006769649.1 2090433 D 1134782 CDS YP_006769650.1 410482104 13693544 2091098..2091850 1 NC_018650.1 COG1126 ABC-type polar amino acid transport system, ATPase component; amino-acid ABC transporter ATP-binding protein YecC 2091850 13693544 O3M_10005 Escherichia coli O104:H4 str. 2009EL-2050 amino-acid ABC transporter ATP-binding protein YecC YP_006769650.1 2091098 D 1134782 CDS YP_006769651.1 410482105 13693545 2092080..2092802 1 NC_018650.1 COG2771 DNA-binding HTH domain-containing proteins; DNA-binding transcriptional activator SdiA 2092802 13693545 O3M_10010 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator SdiA YP_006769651.1 2092080 D 1134782 CDS YP_006769652.1 410482106 13693546 complement(2092870..2093094) 1 NC_018650.1 hypothetical protein 2093094 13693546 O3M_10015 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769652.1 2092870 R 1134782 CDS YP_006769653.1 410482107 13693547 complement(2093081..2093257) 1 NC_018650.1 hypothetical protein 2093257 13693547 O3M_10020 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769653.1 2093081 R 1134782 CDS YP_006769654.1 410482108 13693548 2093553..2094209 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator 2094209 13693548 O3M_10025 Escherichia coli O104:H4 str. 2009EL-2050 response regulator YP_006769654.1 2093553 D 1134782 CDS YP_006769655.1 410482109 13693549 2094206..2096038 1 NC_018650.1 COG0322 Nuclease subunit of the excinuclease complex; excinuclease ABC subunit C 2096038 uvrC 13693549 uvrC Escherichia coli O104:H4 str. 2009EL-2050 excinuclease ABC subunit C YP_006769655.1 2094206 D 1134782 CDS YP_006769656.1 410482110 13693550 2096095..2096643 1 NC_018650.1 COG0558 Phosphatidylglycerophosphate synthase; phosphatidylglycerophosphate synthetase 2096643 13693550 O3M_10035 Escherichia coli O104:H4 str. 2009EL-2050 phosphatidylglycerophosphate synthetase YP_006769656.1 2096095 D 1134782 CDS YP_006769657.1 410482111 13693554 2097293..2097958 1 NC_018650.1 COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; hypothetical protein 2097958 13693554 O3M_10040 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769657.1 2097293 D 1134782 CDS YP_006769658.1 410482112 13693555 complement(2098020..2099231) 1 NC_018650.1 COG0814 Amino acid permeases; tyrosine transporter TyrP 2099231 13693555 O3M_10045 Escherichia coli O104:H4 str. 2009EL-2050 tyrosine transporter TyrP YP_006769658.1 2098020 R 1134782 CDS YP_006769659.1 410482113 13693556 2099421..2099660 1 NC_018650.1 hypothetical protein 2099660 13693556 O3M_10050 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769659.1 2099421 D 1134782 CDS YP_006769660.1 410482114 13693557 complement(2099698..2100195) 1 NC_018650.1 COG1528 Ferritin-like protein; ferritin 2100195 13693557 O3M_10055 Escherichia coli O104:H4 str. 2009EL-2050 ferritin YP_006769660.1 2099698 R 1134782 CDS YP_006769661.1 410482115 13693558 complement(2100367..2100690) 1 NC_018650.1 hypothetical protein 2100690 13693558 O3M_10060 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769661.1 2100367 R 1134782 CDS YP_006769662.1 410482116 13693559 2101154..2101405 1 NC_018650.1 hypothetical protein 2101405 13693559 O3M_10065 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769662.1 2101154 D 1134782 CDS YP_006769663.1 410482117 13693560 complement(2101484..2101987) 1 NC_018650.1 COG1528 Ferritin-like protein; ferritin-like protein 2101987 13693560 O3M_10070 Escherichia coli O104:H4 str. 2009EL-2050 ferritin-like protein YP_006769663.1 2101484 R 1134782 CDS YP_006769664.1 410482118 13693561 2102784..2103773 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; L-arabinose ABC transporter substrate-binding protein 2103773 13693561 O3M_10075 Escherichia coli O104:H4 str. 2009EL-2050 L-arabinose ABC transporter substrate-binding protein YP_006769664.1 2102784 D 1134782 CDS YP_006769665.1 410482119 13693562 2103843..2105357 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; L-arabinose transporter ATP-binding protein 2105357 araG 13693562 araG Escherichia coli O104:H4 str. 2009EL-2050 L-arabinose transporter ATP-binding protein YP_006769665.1 2103843 D 1134782 CDS YP_006769666.1 410482120 13693563 2105372..2106358 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; L-arabinose transporter permease 2106358 araH 13693563 araH Escherichia coli O104:H4 str. 2009EL-2050 L-arabinose transporter permease YP_006769666.1 2105372 D 1134782 CDS YP_006769667.1 410482121 13693564 2106525..2107325 1 NC_018650.1 COG1877 Trehalose-6-phosphatase; trehalose-6-phosphate phosphatase 2107325 13693564 O3M_10090 Escherichia coli O104:H4 str. 2009EL-2050 trehalose-6-phosphate phosphatase YP_006769667.1 2106525 D 1134782 CDS YP_006769668.1 410482122 13693565 2107300..2108724 1 NC_018650.1 COG0380 Trehalose-6-phosphate synthase; trehalose-6-phosphate synthase 2108724 13693565 O3M_10095 Escherichia coli O104:H4 str. 2009EL-2050 trehalose-6-phosphate synthase YP_006769668.1 2107300 D 1134782 CDS YP_006769669.1 410482123 13693566 complement(2108731..2109159) 1 NC_018650.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspC 2109159 13693566 O3M_10100 Escherichia coli O104:H4 str. 2009EL-2050 universal stress protein UspC YP_006769669.1 2108731 R 1134782 CDS YP_006769670.1 410482124 13693567 2109938..2110288 1 NC_018650.1 transcriptional activator FlhD 2110288 13693567 O3M_10105 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator FlhD YP_006769670.1 2109938 D 1134782 CDS YP_006769671.1 410482125 13693568 2110291..2110869 1 NC_018650.1 transcriptional activator FlhC 2110869 13693568 O3M_10110 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator FlhC YP_006769671.1 2110291 D 1134782 CDS YP_006769672.1 410482126 13693569 2110996..2111883 1 NC_018650.1 COG1291 Flagellar motor component; flagellar motor protein MotA 2111883 13693569 O3M_10115 Escherichia coli O104:H4 str. 2009EL-2050 flagellar motor protein MotA YP_006769672.1 2110996 D 1134782 CDS YP_006769673.1 410482127 13693570 2111880..2112806 1 NC_018650.1 COG1360 Flagellar motor protein; flagellar motor protein MotB 2112806 motB 13693570 motB Escherichia coli O104:H4 str. 2009EL-2050 flagellar motor protein MotB YP_006769673.1 2111880 D 1134782 CDS YP_006769674.1 410482128 13693571 2112811..2114775 1 NC_018650.1 COG0643 Chemotaxis protein histidine kinase and related kinases; chemotaxis protein CheA 2114775 13693571 O3M_10125 Escherichia coli O104:H4 str. 2009EL-2050 chemotaxis protein CheA YP_006769674.1 2112811 D 1134782 CDS YP_006769675.1 410482129 13693572 2114796..2115299 1 NC_018650.1 COG0835 Chemotaxis signal transduction protein; purine-binding chemotaxis protein 2115299 13693572 O3M_10130 Escherichia coli O104:H4 str. 2009EL-2050 purine-binding chemotaxis protein YP_006769675.1 2114796 D 1134782 CDS YP_006769676.1 410482130 13693573 2115444..2117105 1 NC_018650.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein II 2117105 13693573 O3M_10135 Escherichia coli O104:H4 str. 2009EL-2050 methyl-accepting chemotaxis protein II YP_006769676.1 2115444 D 1134782 CDS YP_006769677.1 410482131 13693574 2117151..2118752 1 NC_018650.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting protein IV 2118752 13693574 O3M_10140 Escherichia coli O104:H4 str. 2009EL-2050 methyl-accepting protein IV YP_006769677.1 2117151 D 1134782 CDS YP_006769678.1 410482132 13693575 2118771..2119631 1 NC_018650.1 COG1352 Methylase of chemotaxis methyl-accepting proteins; chemotaxis methyltransferase CheR 2119631 13693575 O3M_10145 Escherichia coli O104:H4 str. 2009EL-2050 chemotaxis methyltransferase CheR YP_006769678.1 2118771 D 1134782 CDS YP_006769679.1 410482133 13693576 2119634..2120683 1 NC_018650.1 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; chemotaxis-specific methylesterase 2120683 13693576 O3M_10150 Escherichia coli O104:H4 str. 2009EL-2050 chemotaxis-specific methylesterase YP_006769679.1 2119634 D 1134782 CDS YP_006769680.1 410482134 13693577 2120698..2121087 1 NC_018650.1 COG0784 FOG: CheY-like receiver; chemotaxis regulatory protein CheY 2121087 13693577 O3M_10155 Escherichia coli O104:H4 str. 2009EL-2050 chemotaxis regulatory protein CheY YP_006769680.1 2120698 D 1134782 CDS YP_006769681.1 410482135 13693578 2121098..2121742 1 NC_018650.1 COG3143 Chemotaxis protein; chemotaxis regulator CheZ 2121742 13693578 O3M_10160 Escherichia coli O104:H4 str. 2009EL-2050 chemotaxis regulator CheZ YP_006769681.1 2121098 D 1134782 CDS YP_006769682.1 410482136 13693579 2121944..2123092 1 NC_018650.1 COG1377 Flagellar biosynthesis pathway, component FlhB; flagellar biosynthesis protein FlhB 2123092 flhB 13693579 flhB Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis protein FlhB YP_006769682.1 2121944 D 1134782 CDS YP_006769683.1 410482137 13693580 2123085..2125163 1 NC_018650.1 COG1298 Flagellar biosynthesis pathway, component FlhA; flagellar biosynthesis protein FlhA 2125163 flhA 13693580 flhA Escherichia coli O104:H4 str. 2009EL-2050 flagellar biosynthesis protein FlhA YP_006769683.1 2123085 D 1134782 CDS YP_006769684.1 410482138 13693581 2125163..2125555 1 NC_018650.1 flagellar protein FlhE 2125555 13693581 O3M_10175 Escherichia coli O104:H4 str. 2009EL-2050 flagellar protein FlhE YP_006769684.1 2125163 D 1134782 CDS YP_006769685.1 410482139 13693582 complement(2125675..2126163) 1 NC_018650.1 COG3755 Uncharacterized protein conserved in bacteria; hypothetical protein 2126163 13693582 O3M_10180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769685.1 2125675 R 1134782 CDS YP_006769686.1 410482140 13693583 complement(2126340..2128073) 1 NC_018650.1 COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase 2128073 argS 13693583 argS Escherichia coli O104:H4 str. 2009EL-2050 arginyl-tRNA synthetase YP_006769686.1 2126340 R 1134782 CDS YP_006769687.1 410482141 13693584 2128289..2128855 1 NC_018650.1 COG3102 Uncharacterized protein conserved in bacteria; hypothetical protein 2128855 13693584 O3M_10190 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769687.1 2128289 D 1134782 CDS YP_006769688.1 410482142 13693585 2128869..2129615 1 NC_018650.1 COG3142 Uncharacterized protein involved in copper resistance; copper homeostasis protein CutC 2129615 13693585 O3M_10195 Escherichia coli O104:H4 str. 2009EL-2050 copper homeostasis protein CutC YP_006769688.1 2128869 D 1134782 CDS YP_006769689.1 410482143 13693586 2130003..2131103 1 NC_018650.1 COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; TMAO reductase III (TorYZ), cytochrome c-type subunit TorY 2131103 13693586 O3M_10200 Escherichia coli O104:H4 str. 2009EL-2050 TMAO reductase III (TorYZ), cytochrome c-type subunit TorY YP_006769689.1 2130003 D 1134782 CDS YP_006769690.1 410482144 13693587 2131128..2133557 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; trimethylamine N-oxide reductase system III, catalytic subunit 2133557 13693587 O3M_10205 Escherichia coli O104:H4 str. 2009EL-2050 trimethylamine N-oxide reductase system III, catalytic subunit YP_006769690.1 2131128 D 1134782 CDS YP_006769691.1 410482145 13693588 2133827..2134807 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 2134807 13693588 O3M_10210 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006769691.1 2133827 D 1134782 CDS YP_006769692.1 410482146 13693589 complement(2135001..2135972) 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; tRNA mo(5)U34 methyltransferase 2135972 13693589 O3M_10215 Escherichia coli O104:H4 str. 2009EL-2050 tRNA mo(5)U34 methyltransferase YP_006769692.1 2135001 R 1134782 CDS YP_006769693.1 410482147 13693590 complement(2135969..2136712) 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; tRNA cmo(5)U34 methyltransferase 2136712 13693590 O3M_10220 Escherichia coli O104:H4 str. 2009EL-2050 tRNA cmo(5)U34 methyltransferase YP_006769693.1 2135969 R 1134782 CDS YP_006769694.1 410482148 13693591 complement(2136753..2137148) 1 NC_018650.1 COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily; inner membrane protein 2137148 13693591 O3M_10225 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769694.1 2136753 R 1134782 CDS YP_006769695.1 410482149 13693592 complement(2137201..2137926) 1 NC_018650.1 COG1801 Uncharacterized conserved protein; hypothetical protein 2137926 13693592 O3M_10230 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769695.1 2137201 R 1134782 CDS YP_006769696.1 410482150 13693593 complement(2137953..2139263) 1 NC_018650.1 COG0582 Integrase; integrase 2139263 13693593 O3M_10235 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006769696.1 2137953 R 1134782 CDS YP_006769697.1 410482151 13693594 complement(2139319..2139555) 1 NC_018650.1 excisionase 2139555 13693594 O3M_10240 Escherichia coli O104:H4 str. 2009EL-2050 excisionase YP_006769697.1 2139319 R 1134782 CDS YP_006769698.1 410482152 13693595 complement(2139564..2139710) 1 NC_018650.1 hypothetical protein 2139710 13693595 O3M_10245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769698.1 2139564 R 1134782 CDS YP_006769699.1 410482153 13693596 complement(2139714..2139956) 1 NC_018650.1 hypothetical protein 2139956 13693596 O3M_10250 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769699.1 2139714 R 1134782 CDS YP_006769700.1 410482154 13693597 complement(2140041..2140799) 1 NC_018650.1 hypothetical protein 2140799 13693597 O3M_10255 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769700.1 2140041 R 1134782 CDS YP_006769701.1 410482155 13693598 complement(2140796..2141311) 1 NC_018650.1 hypothetical protein 2141311 13693598 O3M_10260 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769701.1 2140796 R 1134782 CDS YP_006769702.1 410482156 13693599 complement(2141313..2141861) 1 NC_018650.1 EA22-like protein 2141861 13693599 O3M_10265 Escherichia coli O104:H4 str. 2009EL-2050 EA22-like protein YP_006769702.1 2141313 R 1134782 CDS YP_006769703.1 410482157 13693600 complement(2141858..2142097) 1 NC_018650.1 hypothetical protein 2142097 13693600 O3M_10270 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769703.1 2141858 R 1134782 CDS YP_006769704.1 410482158 13693601 complement(2142090..2142293) 1 NC_018650.1 hypothetical protein 2142293 13693601 O3M_10275 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769704.1 2142090 R 1134782 CDS YP_006769705.1 410482159 13693602 complement(2142290..2142652) 1 NC_018650.1 CPS-53 (KpLE1) prophage protein 2142652 13693602 O3M_10280 Escherichia coli O104:H4 str. 2009EL-2050 CPS-53 (KpLE1) prophage protein YP_006769705.1 2142290 R 1134782 CDS YP_006769706.1 410482160 13693603 complement(2142643..2143179) 1 NC_018650.1 COG1896 Predicted hydrolases of HD superfamily; hypothetical protein 2143179 13693603 O3M_10285 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769706.1 2142643 R 1134782 CDS YP_006769707.1 410482161 13693604 complement(2143307..2144131) 1 NC_018650.1 COG5532 Uncharacterized conserved protein; CPS-53 (KpLE1) prophage protein 2144131 13693604 O3M_10290 Escherichia coli O104:H4 str. 2009EL-2050 CPS-53 (KpLE1) prophage protein YP_006769707.1 2143307 R 1134782 CDS YP_006769708.1 410482162 13693605 complement(2145262..2145954) 1 NC_018650.1 COG2932 Predicted transcriptional regulator; repressor protein CI 2145954 13693605 O3M_10295 Escherichia coli O104:H4 str. 2009EL-2050 repressor protein CI YP_006769708.1 2145262 R 1134782 CDS YP_006769709.1 410482163 13693606 2146052..2146312 1 NC_018650.1 COG1396 Predicted transcriptional regulators; hypothetical protein 2146312 13693606 O3M_10300 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769709.1 2146052 D 1134782 CDS YP_006769710.1 410482164 13693607 2146305..2146862 1 NC_018650.1 e14 prophage; nucleic acid-binding protein 2146862 13693607 O3M_10305 Escherichia coli O104:H4 str. 2009EL-2050 nucleic acid-binding protein YP_006769710.1 2146305 D 1134782 CDS YP_006769711.1 410482165 13693608 2146859..2148004 1 NC_018650.1 COG3646 Uncharacterized phage-encoded protein; hypothetical protein 2148004 13693608 O3M_10310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769711.1 2146859 D 1134782 CDS YP_006769712.1 410482166 13693609 2148001..2148225 1 NC_018650.1 hypothetical protein 2148225 13693609 O3M_10315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769712.1 2148001 D 1134782 CDS YP_006769713.1 410482167 13693610 2148222..2149040 1 NC_018650.1 replication protein from phage 2149040 13693610 O3M_10320 Escherichia coli O104:H4 str. 2009EL-2050 replication protein from phage YP_006769713.1 2148222 D 1134782 CDS YP_006769714.1 410482168 13693611 2149037..2149531 1 NC_018650.1 hypothetical protein 2149531 13693611 O3M_10325 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769714.1 2149037 D 1134782 CDS YP_006769715.1 410482169 13693612 2149531..2150184 1 NC_018650.1 phage AdoMet-dependent methyltransferase 2150184 13693612 O3M_10330 Escherichia coli O104:H4 str. 2009EL-2050 phage AdoMet-dependent methyltransferase YP_006769715.1 2149531 D 1134782 CDS YP_006769716.1 410482170 13693613 2150181..2150507 1 NC_018650.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); LexA repressor 2150507 13693613 O3M_10335 Escherichia coli O104:H4 str. 2009EL-2050 LexA repressor YP_006769716.1 2150181 D 1134782 CDS YP_006769717.1 410482171 13693614 2150504..2150899 1 NC_018650.1 COG4570 Holliday junction resolvase; Crossover junction endodeoxyribonuclease 2150899 13693614 O3M_10340 Escherichia coli O104:H4 str. 2009EL-2050 Crossover junction endodeoxyribonuclease YP_006769717.1 2150504 D 1134782 CDS YP_006769718.1 410482172 13693615 2151062..2151877 1 NC_018650.1 hypothetical protein 2151877 13693615 O3M_10345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769718.1 2151062 D 1134782 CDS YP_006769719.1 410482173 13693616 2151879..2152874 1 NC_018650.1 hypothetical protein 2152874 13693616 O3M_10350 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769719.1 2151879 D 1134782 CDS YP_006769720.1 410482174 13693617 2152892..2153248 1 NC_018650.1 antitermination protein from phage origin 2153248 13693617 O3M_10355 Escherichia coli O104:H4 str. 2009EL-2050 antitermination protein from phage origin YP_006769720.1 2152892 D 1134782 CDS YP_006769721.1 410482175 13693618 complement(2153228..2154442) 1 NC_018650.1 hypothetical protein 2154442 13693618 O3M_10360 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769721.1 2153228 R 1134782 CDS YP_006769722.1 410482176 13693619 complement(2154445..2155620) 1 NC_018650.1 COG3081 Nucleoid-associated protein; hypothetical protein 2155620 13693619 O3M_10365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769722.1 2154445 R 1134782 CDS YP_006769723.1 410482177 13693620 2155887..2156084 1 NC_018650.1 hypothetical protein 2156084 13693620 O3M_10370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769723.1 2155887 D 1134782 CDS YP_006769724.1 410482178 13693621 2156345..2156932 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; regulatory protein 2156932 13693621 O3M_10375 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein YP_006769724.1 2156345 D 1134782 CDS YP_006769725.1 410482179 13693625 2157699..2159660 1 NC_018650.1 hypothetical protein 2159660 13693625 O3M_10380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769725.1 2157699 D 1134782 CDS YP_006769726.1 410482180 13693626 2159796..2159990 1 NC_018650.1 hypothetical protein 2159990 13693626 O3M_10385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769726.1 2159796 D 1134782 CDS YP_006769727.1 410482181 13693627 2160016..2160285 1 NC_018650.1 hypothetical protein 2160285 13693627 O3M_10390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769727.1 2160016 D 1134782 CDS YP_006769728.1 410482182 13693628 2160361..2160576 1 NC_018650.1 lysis protein S of prophage CP-933V 2160576 13693628 O3M_10395 Escherichia coli O104:H4 str. 2009EL-2050 lysis protein S of prophage CP-933V YP_006769728.1 2160361 D 1134782 CDS YP_006769729.1 410482183 13693629 2160581..2160925 1 NC_018650.1 hypothetical protein 2160925 13693629 O3M_10400 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769729.1 2160581 D 1134782 CDS YP_006769730.1 410482184 13693630 2160976..2161509 1 NC_018650.1 COG3772 Phage-related lysozyme (muraminidase); phage-related lysozyme (muraminidase) 2161509 13693630 O3M_10405 Escherichia coli O104:H4 str. 2009EL-2050 phage-related lysozyme (muraminidase) YP_006769730.1 2160976 D 1134782 CDS YP_006769731.1 410482185 13693631 2161633..2161806 1 NC_018650.1 hypothetical protein 2161806 13693631 O3M_10410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769731.1 2161633 D 1134782 CDS YP_006769732.1 410482186 13693632 2161808..2162275 1 NC_018650.1 endopeptidase 2162275 13693632 O3M_10415 Escherichia coli O104:H4 str. 2009EL-2050 endopeptidase YP_006769732.1 2161808 D 1134782 CDS YP_006769733.1 410482187 13693633 2162626..2162766 1 NC_018650.1 hypothetical protein 2162766 13693633 O3M_10420 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769733.1 2162626 D 1134782 CDS YP_006769734.1 410482188 13693634 complement(2162899..2163084) 1 NC_018650.1 hypothetical protein 2163084 13693634 O3M_10425 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769734.1 2162899 R 1134782 CDS YP_006769735.1 410482189 13693635 complement(2163100..2163255) 1 NC_018650.1 hypothetical protein 2163255 13693635 O3M_10430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769735.1 2163100 R 1134782 CDS YP_006769736.1 410482190 13693636 2163479..2164027 1 NC_018650.1 COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; prophage Qin DNA packaging protein NU1-like protein 2164027 13693636 O3M_10435 Escherichia coli O104:H4 str. 2009EL-2050 prophage Qin DNA packaging protein NU1-like protein YP_006769736.1 2163479 D 1134782 CDS YP_006769737.1 410482191 13693637 2165912..2166118 1 NC_018650.1 head completion protein 2166118 13693637 O3M_10450 Escherichia coli O104:H4 str. 2009EL-2050 head completion protein YP_006769737.1 2165912 D 1134782 CDS YP_006769738.1 410482192 13693638 2166115..2167707 1 NC_018650.1 COG5511 Bacteriophage capsid protein; head protein Gp4 2167707 13693638 O3M_10455 Escherichia coli O104:H4 str. 2009EL-2050 head protein Gp4 YP_006769738.1 2166115 D 1134782 CDS YP_006769739.1 410482193 13693639 2167697..2169202 1 NC_018650.1 COG0616 Periplasmic serine proteases (ClpP class); head-tail preconnector protein GP5 2169202 13693639 O3M_10460 Escherichia coli O104:H4 str. 2009EL-2050 head-tail preconnector protein GP5 YP_006769739.1 2167697 D 1134782 CDS YP_006769740.1 410482194 13693640 2169239..2169586 1 NC_018650.1 major capsid protein D 2169586 13693640 O3M_10465 Escherichia coli O104:H4 str. 2009EL-2050 major capsid protein D YP_006769740.1 2169239 D 1134782 CDS YP_006769741.1 410482195 13693641 2169644..2170672 1 NC_018650.1 major head protein 2170672 13693641 O3M_10470 Escherichia coli O104:H4 str. 2009EL-2050 major head protein YP_006769741.1 2169644 D 1134782 CDS YP_006769742.1 410482196 13693642 2170725..2171093 1 NC_018650.1 DNA packaging protein from phage origin 2171093 13693642 O3M_10475 Escherichia coli O104:H4 str. 2009EL-2050 DNA packaging protein from phage origin YP_006769742.1 2170725 D 1134782 CDS YP_006769743.1 410482197 13693643 2171086..2171439 1 NC_018650.1 tail attachment protein 2171439 13693643 O3M_10480 Escherichia coli O104:H4 str. 2009EL-2050 tail attachment protein YP_006769743.1 2171086 D 1134782 CDS YP_006769744.1 410482198 13693644 2171455..2172033 1 NC_018650.1 minor tail protein 2172033 13693644 O3M_10485 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein YP_006769744.1 2171455 D 1134782 CDS YP_006769745.1 410482199 13693645 2172030..2172425 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; minor tail protein U 2172425 13693645 O3M_10490 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein U YP_006769745.1 2172030 D 1134782 CDS YP_006769746.1 410482200 13693646 2172433..2173173 1 NC_018650.1 COG5492 Bacterial surface proteins containing Ig-like domains; major tail protein V 2173173 13693646 O3M_10495 Escherichia coli O104:H4 str. 2009EL-2050 major tail protein V YP_006769746.1 2172433 D 1134782 CDS YP_006769747.1 410482201 13693647 2173189..2173611 1 NC_018650.1 minor tail protein 2173611 13693647 O3M_10500 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein YP_006769747.1 2173189 D 1134782 CDS YP_006769748.1 410482202 13693648 2173593..2174027 1 NC_018650.1 minor tail protein T 2174027 13693648 O3M_10505 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein T YP_006769748.1 2173593 D 1134782 CDS YP_006769749.1 410482203 13693649 2174020..2176551 1 NC_018650.1 minor tail protein H 2176551 13693649 O3M_10510 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein H YP_006769749.1 2174020 D 1134782 CDS YP_006769750.1 410482204 13693650 2176579..2176908 1 NC_018650.1 COG4718 Phage-related protein; minor tail protein M 2176908 13693650 O3M_10515 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein M YP_006769750.1 2176579 D 1134782 CDS YP_006769751.1 410482205 13693651 2176908..2177606 1 NC_018650.1 COG4672 Phage-related protein; minor tail protein 2177606 13693651 O3M_10520 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein YP_006769751.1 2176908 D 1134782 CDS YP_006769752.1 410482206 13693652 2177611..2178354 1 NC_018650.1 COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; NLP/P60 protein 2178354 13693652 O3M_10525 Escherichia coli O104:H4 str. 2009EL-2050 NLP/P60 protein YP_006769752.1 2177611 D 1134782 CDS YP_006769753.1 410482207 13693653 2178252..2178923 1 NC_018650.1 COG4723 Phage-related protein, tail component; tail assembly protein I 2178923 13693653 O3M_10530 Escherichia coli O104:H4 str. 2009EL-2050 tail assembly protein I YP_006769753.1 2178252 D 1134782 CDS YP_006769754.1 410482208 13693654 2178984..2182463 1 NC_018650.1 COG4733 Phage-related protein, tail component; Host specificity protein J 2182463 13693654 O3M_10535 Escherichia coli O104:H4 str. 2009EL-2050 Host specificity protein J YP_006769754.1 2178984 D 1134782 CDS YP_006769755.1 410482209 13693655 2182531..2183130 1 NC_018650.1 outer membrane Lom 2183130 13693655 O3M_10540 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane Lom YP_006769755.1 2182531 D 1134782 CDS YP_006769756.1 410482210 13693656 complement(2183779..2184918) 1 NC_018650.1 hypothetical protein 2184918 13693656 O3M_10545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769756.1 2183779 R 1134782 CDS YP_006769757.1 410482211 13693657 2184917..2186452 1 NC_018650.1 tail fiber protein 2186452 13693657 O3M_10550 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber protein YP_006769757.1 2184917 D 1134782 CDS YP_006769758.1 410482212 13693658 2186452..2187036 1 NC_018650.1 Qin prophage; tail fiber chaperone 2187036 13693658 O3M_10555 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber chaperone YP_006769758.1 2186452 D 1134782 CDS YP_006769759.1 410482213 13693659 complement(2187152..2187400) 1 NC_018650.1 DNA-damage-inducible protein 2187400 13693659 O3M_10560 Escherichia coli O104:H4 str. 2009EL-2050 DNA-damage-inducible protein YP_006769759.1 2187152 R 1134782 CDS YP_006769760.1 410482214 13693660 2187497..2187673 1 NC_018650.1 hypothetical protein 2187673 13693660 O3M_10565 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769760.1 2187497 D 1134782 CDS YP_006769761.1 410482215 13693661 complement(2187755..2188321) 1 NC_018650.1 COG1335 Amidases related to nicotinamidase; hydrolase 2188321 13693661 O3M_10570 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006769761.1 2187755 R 1134782 CDS YP_006769762.1 410482216 13693662 2188631..2190403 1 NC_018650.1 COG0173 Aspartyl-tRNA synthetase; aspartyl-tRNA synthetase 2190403 aspS 13693662 aspS Escherichia coli O104:H4 str. 2009EL-2050 aspartyl-tRNA synthetase YP_006769762.1 2188631 D 1134782 CDS YP_006769763.1 410482217 13693663 2190405..2190848 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; dihydroneopterin triphosphate pyrophosphatase 2190848 nudB 13693663 nudB Escherichia coli O104:H4 str. 2009EL-2050 dihydroneopterin triphosphate pyrophosphatase YP_006769763.1 2190405 D 1134782 CDS YP_006769764.1 410482218 13693664 2190877..2191617 1 NC_018650.1 COG0217 Uncharacterized conserved protein; hypothetical protein 2191617 13693664 O3M_10585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769764.1 2190877 D 1134782 CDS YP_006769765.1 410482219 13693665 2191652..2192173 1 NC_018650.1 COG0817 Holliday junction resolvasome, endonuclease subunit; Holliday junction resolvase 2192173 ruvC 13693665 ruvC Escherichia coli O104:H4 str. 2009EL-2050 Holliday junction resolvase YP_006769765.1 2191652 D 1134782 CDS YP_006769766.1 410482220 13693666 complement(2192175..2192777) 1 NC_018650.1 hypothetical protein 2192777 13693666 O3M_10595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769766.1 2192175 R 1134782 CDS YP_006769767.1 410482221 13693667 2193052..2193663 1 NC_018650.1 COG0632 Holliday junction resolvasome, DNA-binding subunit; Holliday junction DNA helicase RuvA 2193663 ruvA 13693667 ruvA Escherichia coli O104:H4 str. 2009EL-2050 Holliday junction DNA helicase RuvA YP_006769767.1 2193052 D 1134782 CDS YP_006769768.1 410482222 13693668 2193672..2194682 1 NC_018650.1 COG2255 Holliday junction resolvasome, helicase subunit; Holliday junction DNA helicase RuvB 2194682 ruvB 13693668 ruvB Escherichia coli O104:H4 str. 2009EL-2050 Holliday junction DNA helicase RuvB YP_006769768.1 2193672 D 1134782 CDS YP_006769769.1 410482223 13693669 complement(2194829..2195614) 1 NC_018650.1 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; high-affinity zinc transporter membrane protein 2195614 znuB 13693669 znuB Escherichia coli O104:H4 str. 2009EL-2050 high-affinity zinc transporter membrane protein YP_006769769.1 2194829 R 1134782 CDS YP_006769770.1 410482224 13693670 complement(2195611..2196366) 1 NC_018650.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; high-affinity zinc transporter ATPase 2196366 znuC 13693670 znuC Escherichia coli O104:H4 str. 2009EL-2050 high-affinity zinc transporter ATPase YP_006769770.1 2195611 R 1134782 CDS YP_006769771.1 410482225 13693671 2196445..2197377 1 NC_018650.1 COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin; high-affinity zinc transporter periplasmic protein 2197377 znuA 13693671 znuA Escherichia coli O104:H4 str. 2009EL-2050 high-affinity zinc transporter periplasmic protein YP_006769771.1 2196445 D 1134782 CDS YP_006769772.1 410482226 13693672 2197393..2198715 1 NC_018650.1 COG0739 Membrane proteins related to metalloendopeptidases; peptidase 2198715 13693672 O3M_10625 Escherichia coli O104:H4 str. 2009EL-2050 peptidase YP_006769772.1 2197393 D 1134782 CDS YP_006769773.1 410482227 13693673 2198835..2199806 1 NC_018650.1 COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2199806 13693673 O3M_10630 Escherichia coli O104:H4 str. 2009EL-2050 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_006769773.1 2198835 D 1134782 CDS YP_006769774.1 410482228 13693674 complement(2199937..2201379) 1 NC_018650.1 COG0469 Pyruvate kinase; pyruvate kinase 2201379 13693674 O3M_10635 Escherichia coli O104:H4 str. 2009EL-2050 pyruvate kinase YP_006769774.1 2199937 R 1134782 CDS YP_006769775.1 410482229 13693675 complement(2201507..2202376) 1 NC_018650.1 COG1737 Transcriptional regulators; DNA-binding transcriptional regulator HexR 2202376 13693675 O3M_10640 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator HexR YP_006769775.1 2201507 R 1134782 CDS YP_006769776.1 410482230 13693676 2202399..2202548 1 NC_018650.1 hypothetical protein 2202548 13693676 O3M_10645 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769776.1 2202399 D 1134782 CDS YP_006769777.1 410482231 13693677 2202714..2204189 1 NC_018650.1 COG0364 Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 2204189 13693677 O3M_10650 Escherichia coli O104:H4 str. 2009EL-2050 glucose-6-phosphate 1-dehydrogenase YP_006769777.1 2202714 D 1134782 CDS YP_006769778.1 410482232 13693678 2204424..2206235 1 NC_018650.1 COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; phosphogluconate dehydratase 2206235 13693678 O3M_10655 Escherichia coli O104:H4 str. 2009EL-2050 phosphogluconate dehydratase YP_006769778.1 2204424 D 1134782 CDS YP_006769779.1 410482233 13693679 2206272..2206913 1 NC_018650.1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2206913 13693679 O3M_10660 Escherichia coli O104:H4 str. 2009EL-2050 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_006769779.1 2206272 D 1134782 CDS YP_006769780.1 410482234 13693680 complement(2206969..2208147) 1 NC_018650.1 COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase); phosphoribosylglycinamide formyltransferase 2 2208147 purT 13693680 purT Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylglycinamide formyltransferase 2 YP_006769780.1 2206969 R 1134782 CDS YP_006769781.1 410482235 13693681 2208281..2208571 1 NC_018650.1 COG3141 Uncharacterized protein conserved in bacteria; DNA damage-inducible protein YebG 2208571 13693681 O3M_10670 Escherichia coli O104:H4 str. 2009EL-2050 DNA damage-inducible protein YebG YP_006769781.1 2208281 D 1134782 CDS YP_006769782.1 410482236 13693682 2208638..2208994 1 NC_018650.1 hypothetical protein 2208994 13693682 O3M_10675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769782.1 2208638 D 1134782 CDS YP_006769783.1 410482237 13693683 complement(2209151..2209261) 1 NC_018650.1 hypothetical protein 2209261 13693683 O3M_10680 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769783.1 2209151 R 1134782 CDS YP_006769784.1 410482238 13693684 2209321..2209980 1 NC_018650.1 COG2979 Uncharacterized protein conserved in bacteria; hypothetical protein 2209980 13693684 O3M_10685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769784.1 2209321 D 1134782 CDS YP_006769785.1 410482239 13693685 2210189..2212249 1 NC_018650.1 COG1770 Protease II; protease 2 2212249 13693685 O3M_10690 Escherichia coli O104:H4 str. 2009EL-2050 protease 2 YP_006769785.1 2210189 D 1134782 CDS YP_006769786.1 410482240 13693686 complement(2212246..2212908) 1 NC_018650.1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; exodeoxyribonuclease X 2212908 13693686 O3M_10695 Escherichia coli O104:H4 str. 2009EL-2050 exodeoxyribonuclease X YP_006769786.1 2212246 R 1134782 CDS YP_006769787.1 410482241 13693687 complement(2212932..2213588) 1 NC_018650.1 COG0388 Predicted amidohydrolase; carbon-nitrogen family hydrolase 2213588 13693687 O3M_10700 Escherichia coli O104:H4 str. 2009EL-2050 carbon-nitrogen family hydrolase YP_006769787.1 2212932 R 1134782 CDS YP_006769788.1 410482242 13693688 complement(2213690..2213920) 1 NC_018650.1 DNA polymerase III subunit theta 2213920 13693688 O3M_10705 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit theta YP_006769788.1 2213690 R 1134782 CDS YP_006769789.1 410482243 13693689 2214059..2214433 1 NC_018650.1 COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; hypothetical protein 2214433 13693689 O3M_10710 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769789.1 2214059 D 1134782 CDS YP_006769790.1 410482244 13693690 2214437..2215309 1 NC_018650.1 COG1276 Putative copper export protein; copper resistance protein D 2215309 13693690 O3M_10715 Escherichia coli O104:H4 str. 2009EL-2050 copper resistance protein D YP_006769790.1 2214437 D 1134782 CDS YP_006769791.1 410482245 13693691 2215322..2215663 1 NC_018650.1 hypothetical protein 2215663 13693691 O3M_10720 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769791.1 2215322 D 1134782 CDS YP_006769792.1 410482246 13693692 2216059..2216715 1 NC_018650.1 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; serine/threonine protein phosphatase 1 2216715 pphA 13693692 pphA Escherichia coli O104:H4 str. 2009EL-2050 serine/threonine protein phosphatase 1 YP_006769792.1 2216059 D 1134782 CDS YP_006769793.1 410482247 13693693 complement(2216716..2216907) 1 NC_018650.1 hypothetical protein 2216907 13693693 O3M_10730 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769793.1 2216716 R 1134782 CDS YP_006769794.1 410482248 13693694 complement(2217012..2217248) 1 NC_018650.1 hypothetical protein 2217248 13693694 O3M_10735 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769794.1 2217012 R 1134782 CDS YP_006769795.1 410482249 13693695 complement(2217366..2218805) 1 NC_018650.1 COG0144 tRNA and rRNA cytosine-C5-methylases; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2218805 yebU 13693695 yebU Escherichia coli O104:H4 str. 2009EL-2050 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_006769795.1 2217366 R 1134782 CDS YP_006769796.1 410482250 13693696 complement(2218885..2221518) 1 NC_018650.1 COG3008 Paraquat-inducible protein B; mce-like protein 2221518 13693696 O3M_10745 Escherichia coli O104:H4 str. 2009EL-2050 mce-like protein YP_006769796.1 2218885 R 1134782 CDS YP_006769797.1 410482251 13693697 complement(2221487..2222770) 1 NC_018650.1 COG2995 Uncharacterized paraquat-inducible protein A; hypothetical protein 2222770 13693697 O3M_10750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769797.1 2221487 R 1134782 CDS YP_006769798.1 410482252 13693698 2222900..2223397 1 NC_018650.1 COG1956 GAF domain-containing protein; hypothetical protein 2223397 13693698 O3M_10755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769798.1 2222900 D 1134782 CDS YP_006769799.1 410482253 13693699 2223494..2224192 1 NC_018650.1 COG3109 Activator of osmoprotectant transporter ProP; ProP expression regulator 2224192 13693699 O3M_10760 Escherichia coli O104:H4 str. 2009EL-2050 ProP expression regulator YP_006769799.1 2223494 D 1134782 CDS YP_006769800.1 410482254 13693700 2224212..2226260 1 NC_018650.1 COG0793 Periplasmic protease; carboxy-terminal protease 2226260 13693700 O3M_10765 Escherichia coli O104:H4 str. 2009EL-2050 carboxy-terminal protease YP_006769800.1 2224212 D 1134782 CDS YP_006769801.1 410482255 13693701 2226452..2227333 1 NC_018650.1 COG0501 Zn-dependent protease with chaperone function; heat shock protein HtpX 2227333 13693701 O3M_10770 Escherichia coli O104:H4 str. 2009EL-2050 heat shock protein HtpX YP_006769801.1 2226452 D 1134782 CDS YP_006769802.1 410482256 13688615 complement(2227379..2228752) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 2228752 13688615 O3M_10775 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769802.1 2227379 R 1134782 CDS YP_006769803.1 410482257 13688616 2228929..2229720 1 NC_018650.1 COG1414 Transcriptional regulator; DNA-binding transcriptional regulator KdgR 2229720 13688616 O3M_10780 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator KdgR YP_006769803.1 2228929 D 1134782 CDS YP_006769804.1 410482258 13688617 complement(2229863..2230078) 1 NC_018650.1 hypothetical protein 2230078 13688617 O3M_10785 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769804.1 2229863 R 1134782 CDS YP_006769805.1 410482259 13688618 2230261..2230404 1 NC_018650.1 PhoPQ regulatory protein 2230404 13688618 O3M_10790 Escherichia coli O104:H4 str. 2009EL-2050 PhoPQ regulatory protein YP_006769805.1 2230261 D 1134782 CDS YP_006769806.1 410482260 13688619 2230479..2230766 1 NC_018650.1 hypothetical protein 2230766 13688619 O3M_10795 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769806.1 2230479 D 1134782 CDS YP_006769807.1 410482261 13688620 2231436..2231579 1 NC_018650.1 hypothetical protein 2231579 13688620 O3M_10800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769807.1 2231436 D 1134782 CDS YP_006769808.1 410482262 13688621 2231592..2231801 1 NC_018650.1 COG1278 Cold shock proteins; cold-shock protein 2231801 13688621 O3M_10805 Escherichia coli O104:H4 str. 2009EL-2050 cold-shock protein YP_006769808.1 2231592 D 1134782 CDS YP_006769809.1 410482263 13688622 2231967..2232776 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; 23S rRNA methyltransferase A 2232776 rrmA 13688622 rrmA Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA methyltransferase A YP_006769809.1 2231967 D 1134782 CDS YP_006769810.1 410482264 13688623 complement(2232773..2233339) 1 NC_018650.1 COG1971 Predicted membrane protein; hypothetical protein 2233339 13688623 O3M_10815 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769810.1 2232773 R 1134782 CDS YP_006769811.1 410482265 13688624 complement(2233768..2234226) 1 NC_018650.1 COG4811 Predicted membrane protein; hypothetical protein 2234226 13688624 O3M_10820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769811.1 2233768 R 1134782 CDS YP_006769812.1 410482266 13688625 complement(2234281..2235141) 1 NC_018650.1 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose-specific transporter subunit IID 2235141 13688625 O3M_10825 Escherichia coli O104:H4 str. 2009EL-2050 PTS system mannose-specific transporter subunit IID YP_006769812.1 2234281 R 1134782 CDS YP_006769813.1 410482267 13688626 complement(2235145..2235945) 1 NC_018650.1 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose-specific transporter subunit IIC 2235945 13688626 O3M_10830 Escherichia coli O104:H4 str. 2009EL-2050 PTS system mannose-specific transporter subunit IIC YP_006769813.1 2235145 R 1134782 CDS YP_006769814.1 410482268 13688627 complement(2236008..2236979) 1 NC_018650.1 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose-specific transporter subunit IIAB 2236979 13688627 O3M_10835 Escherichia coli O104:H4 str. 2009EL-2050 PTS system mannose-specific transporter subunit IIAB YP_006769814.1 2236008 R 1134782 CDS YP_006769815.1 410482269 13688628 2237442..2238998 1 NC_018650.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 2238998 13688628 O3M_10840 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769815.1 2237442 D 1134782 CDS YP_006769816.1 410482270 13688629 complement(2239002..2240600) 1 NC_018650.1 COG2200 FOG: EAL domain; phosphodiesterase 2240600 13688629 O3M_10845 Escherichia coli O104:H4 str. 2009EL-2050 phosphodiesterase YP_006769816.1 2239002 R 1134782 CDS YP_006769817.1 410482271 13688630 complement(2240731..2242095) 1 NC_018650.1 COG1760 L-serine deaminase; L-serine deaminase 2242095 13688630 O3M_10850 Escherichia coli O104:H4 str. 2009EL-2050 L-serine deaminase YP_006769817.1 2240731 R 1134782 CDS YP_006769818.1 410482272 13688631 complement(2242279..2242857) 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase 2242857 13688631 O3M_10855 Escherichia coli O104:H4 str. 2009EL-2050 NUDIX hydrolase YP_006769818.1 2242279 R 1134782 CDS YP_006769819.1 410482273 13688632 complement(2242861..2244222) 1 NC_018650.1 COG0147 Anthranilate/para-aminobenzoate synthases component I; aminodeoxychorismate synthase subunit I 2244222 pabB 13688632 pabB Escherichia coli O104:H4 str. 2009EL-2050 aminodeoxychorismate synthase subunit I YP_006769819.1 2242861 R 1134782 CDS YP_006769820.1 410482274 13688633 2244296..2244475 1 NC_018650.1 COG3140 Uncharacterized protein conserved in bacteria; hypothetical protein 2244475 13688633 O3M_10865 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769820.1 2244296 D 1134782 CDS YP_006769821.1 410482275 13688634 complement(2244595..2244954) 1 NC_018650.1 hypothetical protein 2244954 13688634 O3M_10870 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769821.1 2244595 R 1134782 CDS YP_006769822.1 410482276 13688635 complement(2245317..2245661) 1 NC_018650.1 COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 2245661 13688635 O3M_10875 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769822.1 2245317 R 1134782 CDS YP_006769823.1 410482277 13688636 2245793..2247703 1 NC_018650.1 COG1199 Rad3-related DNA helicases; Helicase c2 2247703 13688636 O3M_10880 Escherichia coli O104:H4 str. 2009EL-2050 Helicase c2 YP_006769823.1 2245793 D 1134782 CDS YP_006769824.1 410482278 13688637 2247761..2248456 1 NC_018650.1 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; peptidase 2248456 13688637 O3M_10885 Escherichia coli O104:H4 str. 2009EL-2050 peptidase YP_006769824.1 2247761 D 1134782 CDS YP_006769825.1 410482279 13688638 2248496..2249077 1 NC_018650.1 COG3065 Starvation-inducible outer membrane lipoprotein; outer membrane lipoprotein 2249077 13688638 O3M_10890 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006769825.1 2248496 D 1134782 CDS YP_006769826.1 410482280 13688639 2249282..2250967 1 NC_018650.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; long-chain-fatty-acid--CoA ligase 2250967 13688639 O3M_10895 Escherichia coli O104:H4 str. 2009EL-2050 long-chain-fatty-acid--CoA ligase YP_006769826.1 2249282 D 1134782 CDS YP_006769827.1 410482281 13688640 2251037..2252164 1 NC_018650.1 COG0349 Ribonuclease D; ribonuclease D 2252164 13688640 O3M_10900 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease D YP_006769827.1 2251037 D 1134782 CDS YP_006769828.1 410482282 13688641 complement(2252218..2253183) 1 NC_018650.1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; oxidoreductase 2253183 13688641 O3M_10905 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006769828.1 2252218 R 1134782 CDS YP_006769829.1 410482283 13688642 complement(2253239..2254363) 1 NC_018650.1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; dioxygenase subunit alpha yeaW 2254363 13688642 O3M_10910 Escherichia coli O104:H4 str. 2009EL-2050 dioxygenase subunit alpha yeaW YP_006769829.1 2253239 R 1134782 CDS YP_006769830.1 410482284 13688643 complement(2254395..2256005) 1 NC_018650.1 COG1292 Choline-glycine betaine transporter; transporter 2256005 13688643 O3M_10915 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769830.1 2254395 R 1134782 CDS YP_006769831.1 410482285 13688644 complement(2256256..2257341) 1 NC_018650.1 COG0473 Isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase 2257341 13688644 O3M_10920 Escherichia coli O104:H4 str. 2009EL-2050 tartrate dehydrogenase YP_006769831.1 2256256 R 1134782 CDS YP_006769832.1 410482286 13688645 2257444..2258367 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2258367 13688645 O3M_10925 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006769832.1 2257444 D 1134782 CDS YP_006769833.1 410482287 13688646 2258494..2259132 1 NC_018650.1 COG1280 Putative threonine efflux protein; leucine export protein LeuE 2259132 13688646 O3M_10930 Escherichia coli O104:H4 str. 2009EL-2050 leucine export protein LeuE YP_006769833.1 2258494 D 1134782 CDS YP_006769834.1 410482288 13688647 2259305..2259664 1 NC_018650.1 COG3615 Uncharacterized protein/domain, possibly involved in tellurite resistance; hypothetical protein 2259664 13688647 O3M_10935 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769834.1 2259305 D 1134782 CDS YP_006769835.1 410482289 13688648 2259668..2259856 1 NC_018650.1 hypothetical protein 2259856 13688648 O3M_10940 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769835.1 2259668 D 1134782 CDS YP_006769836.1 410482290 13688649 2260311..2261519 1 NC_018650.1 COG0675 Transposase and inactivated derivatives; transposase 2261519 13688649 O3M_10945 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006769836.1 2260311 D 1134782 CDS YP_006769837.1 410482291 13688650 2261746..2261994 1 NC_018650.1 COG2261 Predicted membrane protein; hypothetical protein 2261994 13688650 O3M_10950 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769837.1 2261746 D 1134782 CDS YP_006769838.1 410482292 13688651 complement(2262053..2262127) 1 NC_018650.1 hypothetical protein 2262127 13688651 O3M_10955 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769838.1 2262053 R 1134782 CDS YP_006769839.1 410482293 13688652 complement(2262261..2263286) 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 2263286 13688652 O3M_10960 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006769839.1 2262261 R 1134782 CDS YP_006769840.1 410482294 13688653 2263469..2263723 1 NC_018650.1 COG3042 Putative hemolysin; lipoprotein 2263723 13688653 O3M_10965 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006769840.1 2263469 D 1134782 CDS YP_006769841.1 410482295 13688654 complement(2263745..2264092) 1 NC_018650.1 COG3189 Uncharacterized conserved protein; hypothetical protein 2264092 13688654 O3M_10970 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769841.1 2263745 R 1134782 CDS YP_006769842.1 410482296 13688655 complement(2264147..2265328) 1 NC_018650.1 COG2807 Cyanate permease; transporter 2265328 13688655 O3M_10975 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769842.1 2264147 R 1134782 CDS YP_006769843.1 410482297 13688656 2265425..2266246 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator, ARAC-type 2266246 13688656 O3M_10980 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator, ARAC-type YP_006769843.1 2265425 D 1134782 CDS YP_006769844.1 410482298 13688657 complement(2266111..2266653) 1 NC_018650.1 COG2707 Predicted membrane protein; inner membrane protein 2266653 13688657 O3M_10985 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769844.1 2266111 R 1134782 CDS YP_006769845.1 410482299 13688658 2266775..2266927 1 NC_018650.1 hypothetical protein 2266927 13688658 O3M_10990 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769845.1 2266775 D 1134782 CDS YP_006769846.1 410482300 13688659 complement(2266928..2267431) 1 NC_018650.1 COG2606 Uncharacterized conserved protein; hypothetical protein 2267431 13688659 O3M_10995 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769846.1 2266928 R 1134782 CDS YP_006769847.1 410482301 13688660 complement(2267474..2268964) 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 2268964 13688660 O3M_11000 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006769847.1 2267474 R 1134782 CDS YP_006769848.1 410482302 13688661 complement(2269145..2270620) 1 NC_018650.1 COG2199 FOG: GGDEF domain; hypothetical protein 2270620 13688661 O3M_11005 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769848.1 2269145 R 1134782 CDS YP_006769849.1 410482303 13688662 complement(2270767..2272050) 1 NC_018650.1 COG2718 Uncharacterized conserved protein; hypothetical protein 2272050 13688662 O3M_11010 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769849.1 2270767 R 1134782 CDS YP_006769850.1 410482304 13688663 complement(2272163..2274097) 1 NC_018650.1 COG2766 Putative Ser protein kinase; PrkA family serine protein kinase 2274097 13688663 O3M_11015 Escherichia coli O104:H4 str. 2009EL-2050 PrkA family serine protein kinase YP_006769850.1 2272163 R 1134782 CDS YP_006769851.1 410482305 13688664 2274533..2275279 1 NC_018650.1 COG3713 Outer membrane protein V; MltA-interacting protein 2275279 13688664 O3M_11020 Escherichia coli O104:H4 str. 2009EL-2050 MltA-interacting protein YP_006769851.1 2274533 D 1134782 CDS YP_006769852.1 410482306 13688665 2275369..2276223 1 NC_018650.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; oxidoreductase 2276223 13688665 O3M_11025 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006769852.1 2275369 D 1134782 CDS YP_006769853.1 410482307 13688666 complement(2276274..2277158) 1 NC_018650.1 COG0676 Uncharacterized enzymes related to aldose 1-epimerase; aldose 1-epimerase 2277158 13688666 O3M_11030 Escherichia coli O104:H4 str. 2009EL-2050 aldose 1-epimerase YP_006769853.1 2276274 R 1134782 CDS YP_006769854.1 410482308 13688667 complement(2277242..2278237) 1 NC_018650.1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2278237 gapA 13688667 gapA Escherichia coli O104:H4 str. 2009EL-2050 glyceraldehyde-3-phosphate dehydrogenase YP_006769854.1 2277242 R 1134782 CDS YP_006769855.1 410482309 13688668 2278579..2278992 1 NC_018650.1 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; methionine sulfoxide reductase B 2278992 13688668 O3M_11040 Escherichia coli O104:H4 str. 2009EL-2050 methionine sulfoxide reductase B YP_006769855.1 2278579 D 1134782 CDS YP_006769856.1 410482310 13688669 2279034..2279306 1 NC_018650.1 COG3139 Uncharacterized protein conserved in bacteria; hypothetical protein 2279306 13688669 O3M_11045 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769856.1 2279034 D 1134782 CDS YP_006769857.1 410482311 13688670 2279676..2280752 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase zinc-binding dehydrogenase family protein 2280752 13688670 O3M_11050 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase zinc-binding dehydrogenase family protein YP_006769857.1 2279676 D 1134782 CDS YP_006769858.1 410482312 13688671 2280779..2282158 1 NC_018650.1 MFS superfamily protein; COG0477 Permeases of the major facilitator superfamily; transporter 2282158 13688671 O3M_11055 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769858.1 2280779 D 1134782 CDS YP_006769859.1 410482313 13688672 2282175..2283218 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; iditol dehydrogenase 2283218 13688672 O3M_11060 Escherichia coli O104:H4 str. 2009EL-2050 iditol dehydrogenase YP_006769859.1 2282175 D 1134782 CDS YP_006769860.1 410482314 13688673 2283239..2284075 1 NC_018650.1 COG0191 Fructose/tagatose bisphosphate aldolase; aldolase 2284075 13688673 O3M_11065 Escherichia coli O104:H4 str. 2009EL-2050 aldolase YP_006769860.1 2283239 D 1134782 CDS YP_006769861.1 410482315 13688674 2284080..2285027 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; kinase 2285027 13688674 O3M_11070 Escherichia coli O104:H4 str. 2009EL-2050 kinase YP_006769861.1 2284080 D 1134782 CDS YP_006769862.1 410482316 13688675 2285037..2286017 1 NC_018650.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 2286017 13688675 O3M_11075 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006769862.1 2285037 D 1134782 CDS YP_006769863.1 410482317 13688676 2286154..2286912 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DEOR-type transcriptional regulator 2286912 13688676 O3M_11080 Escherichia coli O104:H4 str. 2009EL-2050 DEOR-type transcriptional regulator YP_006769863.1 2286154 D 1134782 CDS YP_006769864.1 410482318 13688677 2287029..2288387 1 NC_018650.1 MFS superfamily protein; COG0477 Permeases of the major facilitator superfamily; transporter 2288387 13688677 O3M_11085 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769864.1 2287029 D 1134782 CDS YP_006769865.1 410482319 13688678 complement(2288480..2289121) 1 NC_018650.1 COG1335 Amidases related to nicotinamidase; nicotinamidase/pyrazinamidase 2289121 13688678 O3M_11090 Escherichia coli O104:H4 str. 2009EL-2050 nicotinamidase/pyrazinamidase YP_006769865.1 2288480 R 1134782 CDS YP_006769866.1 410482320 13688679 complement(2289132..2290148) 1 NC_018650.1 COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; asparaginase 2290148 ansA 13688679 ansA Escherichia coli O104:H4 str. 2009EL-2050 asparaginase YP_006769866.1 2289132 R 1134782 CDS YP_006769867.1 410482321 13688680 complement(2290315..2292171) 1 NC_018650.1 COG0616 Periplasmic serine proteases (ClpP class); protease 4 2292171 13688680 O3M_11100 Escherichia coli O104:H4 str. 2009EL-2050 protease 4 YP_006769867.1 2290315 R 1134782 CDS YP_006769868.1 410482322 13688681 2292332..2292883 1 NC_018650.1 COG0778 Nitroreductase; oxidoreductase 2292883 13688681 O3M_11105 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006769868.1 2292332 D 1134782 CDS YP_006769869.1 410482323 13688682 2293000..2294043 1 NC_018650.1 COG0709 Selenophosphate synthase; selenophosphate synthetase 2294043 13688682 O3M_11110 Escherichia coli O104:H4 str. 2009EL-2050 selenophosphate synthetase YP_006769869.1 2293000 D 1134782 CDS YP_006769870.1 410482324 13688683 2294048..2296009 1 NC_018650.1 COG0550 Topoisomerase IA; DNA topoisomerase III 2296009 13688683 O3M_11115 Escherichia coli O104:H4 str. 2009EL-2050 DNA topoisomerase III YP_006769870.1 2294048 D 1134782 CDS YP_006769871.1 410482325 13688684 2296137..2296664 1 NC_018650.1 hypothetical protein 2296664 13688684 O3M_11120 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769871.1 2296137 D 1134782 CDS YP_006769872.1 410482326 13688685 2296710..2297690 1 NC_018650.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 2297690 13688685 O3M_11125 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006769872.1 2296710 D 1134782 CDS YP_006769873.1 410482327 13688686 2297936..2298376 1 NC_018650.1 hypothetical protein 2298376 13688686 O3M_11130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769873.1 2297936 D 1134782 CDS YP_006769874.1 410482328 13688687 complement(2298493..2299836) 1 NC_018650.1 COG0334 Glutamate dehydrogenase/leucine dehydrogenase; glutamate dehydrogenase 2299836 13688687 O3M_11135 Escherichia coli O104:H4 str. 2009EL-2050 glutamate dehydrogenase YP_006769874.1 2298493 R 1134782 CDS YP_006769875.1 410482329 13688688 2300072..2300344 1 NC_018650.1 hypothetical protein 2300344 13688688 O3M_11140 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769875.1 2300072 D 1134782 CDS YP_006769876.1 410482330 13688689 complement(2300310..2300717) 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2300717 13688689 O3M_11145 Escherichia coli O104:H4 str. 2009EL-2050 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_006769876.1 2300310 R 1134782 CDS YP_006769877.1 410482331 13688690 2300804..2301424 1 NC_018650.1 COG0558 Phosphatidylglycerophosphate synthase; phosphatidyl transferase, inner membrane protein 2301424 13688690 O3M_11150 Escherichia coli O104:H4 str. 2009EL-2050 phosphatidyl transferase, inner membrane protein YP_006769877.1 2300804 D 1134782 CDS YP_006769878.1 410482332 13688691 complement(2301433..2302740) 1 NC_018650.1 COG2897 Rhodanese-related sulfurtransferase; thiosulfate sulfur transferase / thiosulfate binding protein 2302740 13688691 O3M_11155 Escherichia coli O104:H4 str. 2009EL-2050 thiosulfate sulfur transferase / thiosulfate binding protein YP_006769878.1 2301433 R 1134782 CDS YP_006769879.1 410482333 13688692 complement(2302807..2303460) 1 NC_018650.1 COG4136 ABC-type uncharacterized transport system, ATPase component; transporter subunit 2303460 13688692 O3M_11160 Escherichia coli O104:H4 str. 2009EL-2050 transporter subunit YP_006769879.1 2302807 R 1134782 CDS YP_006769880.1 410482334 13688693 complement(2303460..2304995) 1 NC_018650.1 COG4135 ABC-type uncharacterized transport system, permease component; ABC transporter membrane protein 2304995 13688693 O3M_11165 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter membrane protein YP_006769880.1 2303460 R 1134782 CDS YP_006769881.1 410482335 13688694 complement(2304968..2306134) 1 NC_018650.1 COG4134 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein 2306134 13688694 O3M_11170 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769881.1 2304968 R 1134782 CDS YP_006769882.1 410482336 13688695 complement(2306144..2306692) 1 NC_018650.1 COG2128 Uncharacterized conserved protein; carboxymuconolactone decarboxylase family protein 2306692 13688695 O3M_11175 Escherichia coli O104:H4 str. 2009EL-2050 carboxymuconolactone decarboxylase family protein YP_006769882.1 2306144 R 1134782 CDS YP_006769883.1 410482337 13688696 complement(2306692..2307399) 1 NC_018650.1 COG0398 Uncharacterized conserved protein; inner membrane protein 2307399 13688696 O3M_11180 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769883.1 2306692 R 1134782 CDS YP_006769884.1 410482338 13688697 complement(2307413..2308090) 1 NC_018650.1 hypothetical protein 2308090 13688697 O3M_11185 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769884.1 2307413 R 1134782 CDS YP_006769885.1 410482339 13688698 complement(2308095..2308805) 1 NC_018650.1 COG0398 Uncharacterized conserved protein; inner membrane protein 2308805 13688698 O3M_11190 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769885.1 2308095 R 1134782 CDS YP_006769886.1 410482340 13688699 complement(2308972..2309778) 1 NC_018650.1 COG0708 Exonuclease III; exonuclease III 2309778 13688699 O3M_11195 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease III YP_006769886.1 2308972 R 1134782 CDS YP_006769887.1 410482341 13688700 2310224..2311444 1 NC_018650.1 COG4992 Ornithine/acetylornithine aminotransferase; bifunctional succinylornithine transaminase/acetylornithine transaminase 2311444 13688700 O3M_11200 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_006769887.1 2310224 D 1134782 CDS YP_006769888.1 410482342 13688701 2311441..2312475 1 NC_018650.1 COG3138 Arginine/ornithine N-succinyltransferase beta subunit; arginine succinyltransferase 2312475 13688701 O3M_11205 Escherichia coli O104:H4 str. 2009EL-2050 arginine succinyltransferase YP_006769888.1 2311441 D 1134782 CDS YP_006769889.1 410482343 13688702 2312472..2313950 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; succinylglutamic semialdehyde dehydrogenase 2313950 astD 13688702 astD Escherichia coli O104:H4 str. 2009EL-2050 succinylglutamic semialdehyde dehydrogenase YP_006769889.1 2312472 D 1134782 CDS YP_006769890.1 410482344 13688703 2313947..2315290 1 NC_018650.1 COG3724 Succinylarginine dihydrolase; succinylarginine dihydrolase 2315290 13688703 O3M_11215 Escherichia coli O104:H4 str. 2009EL-2050 succinylarginine dihydrolase YP_006769890.1 2313947 D 1134782 CDS YP_006769891.1 410482345 13688704 2315283..2316251 1 NC_018650.1 COG2988 Succinylglutamate desuccinylase; succinylglutamate desuccinylase 2316251 13688704 O3M_11220 Escherichia coli O104:H4 str. 2009EL-2050 succinylglutamate desuccinylase YP_006769891.1 2315283 D 1134782 CDS YP_006769892.1 410482346 13688705 2316581..2317066 1 NC_018650.1 COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; hypothetical protein 2317066 13688705 O3M_11225 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769892.1 2316581 D 1134782 CDS YP_006769893.1 410482347 13688706 2317269..2317844 1 NC_018650.1 COG3758 Uncharacterized protein conserved in bacteria; hypothetical protein 2317844 13688706 O3M_11230 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769893.1 2317269 D 1134782 CDS YP_006769894.1 410482348 13688707 complement(2317804..2318691) 1 NC_018650.1 COG0322 Nuclease subunit of the excinuclease complex; nucleotide excision repair endonuclease 2318691 13688707 O3M_11235 Escherichia coli O104:H4 str. 2009EL-2050 nucleotide excision repair endonuclease YP_006769894.1 2317804 R 1134782 CDS YP_006769895.1 410482349 13688708 2318761..2318910 1 NC_018650.1 hypothetical protein 2318910 13688708 O3M_11240 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769895.1 2318761 D 1134782 CDS YP_006769896.1 410482350 13688709 complement(2318921..2319748) 1 NC_018650.1 COG0171 NAD synthase; NAD synthetase 2319748 nadE 13688709 nadE Escherichia coli O104:H4 str. 2009EL-2050 NAD synthetase YP_006769896.1 2318921 R 1134782 CDS YP_006769897.1 410482351 13688710 2319950..2320288 1 NC_018650.1 DNA-binding transcriptional activator OsmE 2320288 13688710 O3M_11250 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator OsmE YP_006769897.1 2319950 D 1134782 CDS YP_006769898.1 410482352 13688711 2320587..2320907 1 NC_018650.1 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2320907 13688711 O3M_11255 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_006769898.1 2320587 D 1134782 CDS YP_006769899.1 410482353 13688712 2320992..2322350 1 NC_018650.1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2322350 13688712 O3M_11260 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_006769899.1 2320992 D 1134782 CDS YP_006769900.1 410482354 13688713 2322401..2322751 1 NC_018650.1 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2322751 13688713 O3M_11265 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_006769900.1 2322401 D 1134782 CDS YP_006769901.1 410482355 13688714 2322759..2323601 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator ChbR 2323601 13688714 O3M_11270 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator ChbR YP_006769901.1 2322759 D 1134782 CDS YP_006769902.1 410482356 13688715 2323706..2325058 1 NC_018650.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; cryptic phospho-beta-glucosidase, NAD(P)-binding protein 2325058 13688715 O3M_11275 Escherichia coli O104:H4 str. 2009EL-2050 cryptic phospho-beta-glucosidase, NAD(P)-binding protein YP_006769902.1 2323706 D 1134782 CDS YP_006769903.1 410482357 13688716 2325071..2325829 1 NC_018650.1 COG3394 Uncharacterized protein conserved in bacteria; hypothetical protein 2325829 13688716 O3M_11280 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769903.1 2325071 D 1134782 CDS YP_006769904.1 410482358 13688717 complement(2325876..2328137) 1 NC_018650.1 COG0753 Catalase; hydroperoxidase II 2328137 katE 13688717 katE Escherichia coli O104:H4 str. 2009EL-2050 hydroperoxidase II YP_006769904.1 2325876 R 1134782 CDS YP_006769905.1 410482359 13688718 2328341..2328583 1 NC_018650.1 cell division modulator 2328583 13688718 O3M_11290 Escherichia coli O104:H4 str. 2009EL-2050 cell division modulator YP_006769905.1 2328341 D 1134782 CDS YP_006769906.1 410482360 13688719 2328872..2329228 1 NC_018650.1 hypothetical protein 2329228 13688719 O3M_11295 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769906.1 2328872 D 1134782 CDS YP_006769907.1 410482361 13688720 2329238..2329675 1 NC_018650.1 hypothetical protein 2329675 13688720 O3M_11300 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769907.1 2329238 D 1134782 CDS YP_006769908.1 410482362 13688721 complement(2329679..2331070) 1 NC_018650.1 COG1823 Predicted Na+/dicarboxylate symporter; cation-acid symporter 2331070 13688721 O3M_11305 Escherichia coli O104:H4 str. 2009EL-2050 cation-acid symporter YP_006769908.1 2329679 R 1134782 CDS YP_006769909.1 410482363 13688722 complement(2331203..2331793) 1 NC_018650.1 COG1988 Predicted membrane-bound metal-dependent hydrolases; inner membrane protein 2331793 13688722 O3M_11310 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769909.1 2331203 R 1134782 CDS YP_006769910.1 410482364 13688723 complement(2331956..2332624) 1 NC_018650.1 COG0637 Predicted phosphatase/phosphohexomutase; 2-deoxyglucose-6-phosphatase 2332624 13688723 O3M_11315 Escherichia coli O104:H4 str. 2009EL-2050 2-deoxyglucose-6-phosphatase YP_006769910.1 2331956 R 1134782 CDS YP_006769911.1 410482365 13688724 2332771..2333307 1 NC_018650.1 inner membrane protein 2333307 13688724 O3M_11320 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769911.1 2332771 D 1134782 CDS YP_006769912.1 410482366 13688725 complement(2333348..2334208) 1 NC_018650.1 COG3001 Fructosamine-3-kinase; phosphotransferase/kinase 2334208 13688725 O3M_11325 Escherichia coli O104:H4 str. 2009EL-2050 phosphotransferase/kinase YP_006769912.1 2333348 R 1134782 CDS YP_006769913.1 410482367 13688726 complement(2334314..2334604) 1 NC_018650.1 hypothetical protein 2334604 13688726 O3M_11330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769913.1 2334314 R 1134782 CDS YP_006769914.1 410482368 13688727 complement(2334705..2335634) 1 NC_018650.1 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); 6-phosphofructokinase 2335634 13688727 O3M_11335 Escherichia coli O104:H4 str. 2009EL-2050 6-phosphofructokinase YP_006769914.1 2334705 R 1134782 CDS YP_006769915.1 410482369 13688728 2335921..2336679 1 NC_018650.1 COG3137 Putative salt-induced outer membrane protein; hypothetical protein 2336679 13688728 O3M_11340 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769915.1 2335921 D 1134782 CDS YP_006769916.1 410482370 13688729 complement(2336732..2336839) 1 NC_018650.1 hypothetical protein 2336839 13688729 O3M_11345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769916.1 2336732 R 1134782 CDS YP_006769917.1 410482371 13688730 2339437..2341365 1 NC_018650.1 COG0441 Threonyl-tRNA synthetase; threonyl-tRNA synthetase 2341365 thrS 13688730 thrS Escherichia coli O104:H4 str. 2009EL-2050 threonyl-tRNA synthetase YP_006769917.1 2339437 D 1134782 CDS YP_006769918.1 410482372 13688731 2341477..2341911 1 NC_018650.1 COG0290 Translation initiation factor 3 (IF-3); translation initiation factor IF-3 2341911 infC 13688731 infC Escherichia coli O104:H4 str. 2009EL-2050 translation initiation factor IF-3 YP_006769918.1 2341477 D 1134782 CDS YP_006769919.1 410482373 13688732 2342008..2342205 1 NC_018650.1 COG0291 Ribosomal protein L35; 50S ribosomal protein L35 2342205 rpmI 13688732 rpmI Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L35 YP_006769919.1 2342008 D 1134782 CDS YP_006769920.1 410482374 13688733 2342258..2342614 1 NC_018650.1 COG0292 Ribosomal protein L20; 50S ribosomal protein L20 2342614 rplT 13688733 rplT Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L20 YP_006769920.1 2342258 D 1134782 CDS YP_006769921.1 410482375 13688734 2343064..2344047 1 NC_018650.1 COG0016 Phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 2344047 pheS 13688734 pheS Escherichia coli O104:H4 str. 2009EL-2050 phenylalanyl-tRNA synthetase subunit alpha YP_006769921.1 2343064 D 1134782 CDS YP_006769922.1 410482376 13688735 2344062..2346449 1 NC_018650.1 COG0073 EMAP domain; phenylalanyl-tRNA synthetase subunit beta 2346449 pheT 13688735 pheT Escherichia coli O104:H4 str. 2009EL-2050 phenylalanyl-tRNA synthetase subunit beta YP_006769922.1 2344062 D 1134782 CDS YP_006769923.1 410482377 13688736 2346454..2346753 1 NC_018650.1 COG0776 Bacterial nucleoid DNA-binding protein; integration host factor subunit alpha 2346753 ihfA 13688736 ihfA Escherichia coli O104:H4 str. 2009EL-2050 integration host factor subunit alpha YP_006769923.1 2346454 D 1134782 CDS YP_006769924.1 410482378 13688737 complement(2347055..2347195) 1 NC_018650.1 hypothetical protein 2347195 13688737 O3M_11395 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769924.1 2347055 R 1134782 CDS YP_006769925.1 410482379 13688738 complement(2347386..2347646) 1 NC_018650.1 COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; prophage late promoter activator protein 2347646 13688738 O3M_11400 Escherichia coli O104:H4 str. 2009EL-2050 prophage late promoter activator protein YP_006769925.1 2347386 R 1134782 CDS YP_006769926.1 410482380 13688739 2347879..2349048 1 NC_018650.1 hypothetical protein 2349048 13688739 O3M_11405 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769926.1 2347879 D 1134782 CDS YP_006769927.1 410482381 13688740 complement(2349140..2350249) 1 NC_018650.1 COG3500 Phage protein D; phage protein D 2350249 13688740 O3M_11410 Escherichia coli O104:H4 str. 2009EL-2050 phage protein D YP_006769927.1 2349140 R 1134782 CDS YP_006769928.1 410482382 13688741 2350407..2351591 1 NC_018650.1 COG3497 Phage tail sheath protein FI; tail sheath protein 2351591 13688741 O3M_11415 Escherichia coli O104:H4 str. 2009EL-2050 tail sheath protein YP_006769928.1 2350407 D 1134782 CDS YP_006769929.1 410482383 13688742 2351591..2352103 1 NC_018650.1 COG3498 Phage tail tube protein FII; tail tube protein 2352103 13688742 O3M_11420 Escherichia coli O104:H4 str. 2009EL-2050 tail tube protein YP_006769929.1 2351591 D 1134782 CDS YP_006769930.1 410482384 13688743 2352158..2352523 1 NC_018650.1 tail protein 2352523 13688743 O3M_11425 Escherichia coli O104:H4 str. 2009EL-2050 tail protein YP_006769930.1 2352158 D 1134782 CDS YP_006769931.1 410482385 13688744 2352451..2352687 1 NC_018650.1 phage tail protein 2352687 13688744 O3M_11430 Escherichia coli O104:H4 str. 2009EL-2050 phage tail protein YP_006769931.1 2352451 D 1134782 CDS YP_006769932.1 410482386 13688745 2352674..2355481 1 NC_018650.1 COG5283 Phage-related tail protein; tail protein (modular protein) 2355481 13688745 O3M_11435 Escherichia coli O104:H4 str. 2009EL-2050 tail protein (modular protein) YP_006769932.1 2352674 D 1134782 CDS YP_006769933.1 410482387 13688746 2355494..2355982 1 NC_018650.1 COG3499 Phage protein U; tail fiber protein 2355982 13688746 O3M_11440 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber protein YP_006769933.1 2355494 D 1134782 CDS YP_006769934.1 410482388 13688747 2356139..2356711 1 NC_018650.1 COG1045 Serine acetyltransferase; acetyltransferase 2356711 13688747 O3M_11445 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006769934.1 2356139 D 1134782 CDS YP_006769935.1 410482389 13688748 complement(2356755..2357333) 1 NC_018650.1 tail fiber assembly protein 2357333 13688748 O3M_11450 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber assembly protein YP_006769935.1 2356755 R 1134782 CDS YP_006769936.1 410482390 13688749 complement(2357333..2359465) 1 NC_018650.1 COG5301 Phage-related tail fibre protein; side tail fiber protein 2359465 13688749 O3M_11455 Escherichia coli O104:H4 str. 2009EL-2050 side tail fiber protein YP_006769936.1 2357333 R 1134782 CDS YP_006769937.1 410482391 13688750 complement(2359468..2359998) 1 NC_018650.1 COG4385 Bacteriophage P2-related tail formation protein; phage tail protein 2359998 13688750 O3M_11460 Escherichia coli O104:H4 str. 2009EL-2050 phage tail protein YP_006769937.1 2359468 R 1134782 CDS YP_006769938.1 410482392 13688751 complement(2359991..2360887) 1 NC_018650.1 COG3948 Phage-related baseplate assembly protein; baseplate assembly protein 2360887 13688751 O3M_11465 Escherichia coli O104:H4 str. 2009EL-2050 baseplate assembly protein YP_006769938.1 2359991 R 1134782 CDS YP_006769939.1 410482393 13688752 complement(2360891..2361241) 1 NC_018650.1 COG3628 Phage baseplate assembly protein W; phage baseplate assembly protein 2361241 13688752 O3M_11470 Escherichia coli O104:H4 str. 2009EL-2050 phage baseplate assembly protein YP_006769939.1 2360891 R 1134782 CDS YP_006769940.1 410482394 13688753 complement(2361238..2361819) 1 NC_018650.1 COG4540 Phage P2 baseplate assembly protein gpV; baseplate assembly protein 2361819 13688753 O3M_11475 Escherichia coli O104:H4 str. 2009EL-2050 baseplate assembly protein YP_006769940.1 2361238 R 1134782 CDS YP_006769941.1 410482395 13688754 complement(2361816..2362460) 1 NC_018650.1 phage tail completion protein S 2362460 13688754 O3M_11480 Escherichia coli O104:H4 str. 2009EL-2050 phage tail completion protein S YP_006769941.1 2361816 R 1134782 CDS YP_006769942.1 410482396 13688755 complement(2362444..2362911) 1 NC_018650.1 Phage tail completion protein R 2362911 13688755 O3M_11485 Escherichia coli O104:H4 str. 2009EL-2050 Phage tail completion protein R YP_006769942.1 2362444 R 1134782 CDS YP_006769943.1 410482397 13688756 complement(2362935..2364815) 1 NC_018650.1 hypothetical protein 2364815 13688756 O3M_11490 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769943.1 2362935 R 1134782 CDS YP_006769944.1 410482398 13688757 complement(2364954..2365361) 1 NC_018650.1 COG0164 Ribonuclease HII; hypothetical protein 2365361 13688757 O3M_11495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769944.1 2364954 R 1134782 CDS YP_006769945.1 410482399 13688758 complement(2365358..2365750) 1 NC_018650.1 endolysin 2365750 13688758 O3M_11500 Escherichia coli O104:H4 str. 2009EL-2050 endolysin YP_006769945.1 2365358 R 1134782 CDS YP_006769946.1 410482400 13688759 complement(2365747..2366070) 1 NC_018650.1 phage holin 2366070 13688759 O3M_11505 Escherichia coli O104:H4 str. 2009EL-2050 phage holin YP_006769946.1 2365747 R 1134782 CDS YP_006769947.1 410482401 13688760 complement(2366073..2366273) 1 NC_018650.1 COG5004 P2-like prophage tail protein X; phage tail protein 2366273 13688760 O3M_11510 Escherichia coli O104:H4 str. 2009EL-2050 phage tail protein YP_006769947.1 2366073 R 1134782 CDS YP_006769948.1 410482402 13688761 complement(2366273..2366767) 1 NC_018650.1 capsid completion protein 2366767 13688761 O3M_11515 Escherichia coli O104:H4 str. 2009EL-2050 capsid completion protein YP_006769948.1 2366273 R 1134782 CDS YP_006769949.1 410482403 13688762 complement(2366869..2367669) 1 NC_018650.1 terminase, endonuclease subunit 2367669 13688762 O3M_11520 Escherichia coli O104:H4 str. 2009EL-2050 terminase, endonuclease subunit YP_006769949.1 2366869 R 1134782 CDS YP_006769950.1 410482404 13688763 complement(2367715..2368767) 1 NC_018650.1 major capsid protein 2368767 13688763 O3M_11525 Escherichia coli O104:H4 str. 2009EL-2050 major capsid protein YP_006769950.1 2367715 R 1134782 CDS YP_006769951.1 410482405 13688764 complement(2368791..2369627) 1 NC_018650.1 capsid scaffolding protein 2369627 13688764 O3M_11530 Escherichia coli O104:H4 str. 2009EL-2050 capsid scaffolding protein YP_006769951.1 2368791 R 1134782 CDS YP_006769952.1 410482406 13688765 2369782..2371533 1 NC_018650.1 COG5484 Uncharacterized conserved protein; large subunit terminase 2371533 13688765 O3M_11535 Escherichia coli O104:H4 str. 2009EL-2050 large subunit terminase YP_006769952.1 2369782 D 1134782 CDS YP_006769953.1 410482407 13688766 2371533..2372579 1 NC_018650.1 COG5518 Bacteriophage capsid portal protein; capsid portal protein 2372579 13688766 O3M_11540 Escherichia coli O104:H4 str. 2009EL-2050 capsid portal protein YP_006769953.1 2371533 D 1134782 CDS YP_006769954.1 410482408 13688767 complement(2373091..2373354) 1 NC_018650.1 hypothetical protein 2373354 13688767 O3M_11545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769954.1 2373091 R 1134782 CDS YP_006769955.1 410482409 13688768 complement(2373356..2373787) 1 NC_018650.1 hypothetical protein 2373787 13688768 O3M_11550 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769955.1 2373356 R 1134782 CDS YP_006769956.1 410482410 13688769 complement(2373807..2374121) 1 NC_018650.1 plasmid partition protein; modular protein; stability/partitioning protein phage encoded 2374121 13688769 O3M_11555 Escherichia coli O104:H4 str. 2009EL-2050 stability/partitioning protein phage encoded YP_006769956.1 2373807 R 1134782 CDS YP_006769957.1 410482411 13688770 complement(2374126..2375085) 1 NC_018650.1 COG0443 Molecular chaperone; prophage stability/partitioning protein 2375085 13688770 O3M_11560 Escherichia coli O104:H4 str. 2009EL-2050 prophage stability/partitioning protein YP_006769957.1 2374126 R 1134782 CDS YP_006769958.1 410482412 13688771 complement(2375162..2378002) 1 NC_018650.1 phage replication protein 2378002 13688771 O3M_11565 Escherichia coli O104:H4 str. 2009EL-2050 phage replication protein YP_006769958.1 2375162 R 1134782 CDS YP_006769959.1 410482413 13688772 complement(2377999..2378388) 1 NC_018650.1 hypothetical protein 2378388 13688772 O3M_11570 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769959.1 2377999 R 1134782 CDS YP_006769960.1 410482414 13688773 complement(2378461..2378691) 1 NC_018650.1 hypothetical protein 2378691 13688773 O3M_11575 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769960.1 2378461 R 1134782 CDS YP_006769961.1 410482415 13688774 complement(2379014..2379313) 1 NC_018650.1 hypothetical protein 2379313 13688774 O3M_11580 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769961.1 2379014 R 1134782 CDS YP_006769962.1 410482416 13688775 complement(2379310..2379555) 1 NC_018650.1 COG1846 Transcriptional regulators; hypothetical protein 2379555 13688775 O3M_11585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769962.1 2379310 R 1134782 CDS YP_006769963.1 410482417 13688776 complement(2379552..2379755) 1 NC_018650.1 hypothetical protein 2379755 13688776 O3M_11590 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769963.1 2379552 R 1134782 CDS YP_006769964.1 410482418 13688777 complement(2379745..2380065) 1 NC_018650.1 hypothetical protein 2380065 13688777 O3M_11595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769964.1 2379745 R 1134782 CDS YP_006769965.1 410482419 13688778 complement(2380154..2380267) 1 NC_018650.1 hypothetical protein 2380267 13688778 O3M_11600 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769965.1 2380154 R 1134782 CDS YP_006769966.1 410482420 13688779 complement(2380264..2380506) 1 NC_018650.1 hypothetical protein 2380506 13688779 O3M_11605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769966.1 2380264 R 1134782 CDS YP_006769967.1 410482421 13688780 complement(2380518..2380805) 1 NC_018650.1 hypothetical protein 2380805 13688780 O3M_11610 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769967.1 2380518 R 1134782 CDS YP_006769968.1 410482422 13688781 complement(2380816..2381154) 1 NC_018650.1 hypothetical protein 2381154 13688781 O3M_11615 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769968.1 2380816 R 1134782 CDS YP_006769969.1 410482423 13688782 complement(2381169..2381447) 1 NC_018650.1 DNA-binding protein 2381447 13688782 O3M_11620 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding protein YP_006769969.1 2381169 R 1134782 CDS YP_006769970.1 410482424 13688783 2381539..2381850 1 NC_018650.1 COG2944 Predicted transcriptional regulator; repressor protein C 2381850 13688783 O3M_11625 Escherichia coli O104:H4 str. 2009EL-2050 repressor protein C YP_006769970.1 2381539 D 1134782 CDS YP_006769971.1 410482425 13688784 2381939..2382874 1 NC_018650.1 COG0582 Integrase; integrase 2382874 13688784 O3M_11630 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006769971.1 2381939 D 1134782 CDS YP_006769972.1 410482426 13688785 2382885..2383280 1 NC_018650.1 hypothetical protein 2383280 13688785 O3M_11635 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769972.1 2382885 D 1134782 CDS YP_006769973.1 410482427 13688786 2383470..2384450 1 NC_018650.1 COG4139 ABC-type cobalamin transport system, permease component; vtamin B12-transporter permease 2384450 13688786 O3M_11640 Escherichia coli O104:H4 str. 2009EL-2050 vtamin B12-transporter permease YP_006769973.1 2383470 D 1134782 CDS YP_006769974.1 410482428 13688787 2384513..2385064 1 NC_018650.1 COG0386 Glutathione peroxidase; glutathione peroxidase 2385064 btuE 13688787 btuE Escherichia coli O104:H4 str. 2009EL-2050 glutathione peroxidase YP_006769974.1 2384513 D 1134782 CDS YP_006769975.1 410482429 13688788 2385064..2385813 1 NC_018650.1 COG4138 ABC-type cobalamin transport system, ATPase component; vitamin B12-transporter ATPase 2385813 13688788 O3M_11650 Escherichia coli O104:H4 str. 2009EL-2050 vitamin B12-transporter ATPase YP_006769975.1 2385064 D 1134782 CDS YP_006769976.1 410482430 13688789 2385891..2386355 1 NC_018650.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); lipoprotein 2386355 13688789 O3M_11655 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006769976.1 2385891 D 1134782 CDS YP_006769977.1 410482431 13688790 2386602..2387315 1 NC_018650.1 COG2200 FOG: EAL domain; hypothetical protein 2387315 13688790 O3M_11660 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769977.1 2386602 D 1134782 CDS YP_006769978.1 410482432 13688791 2387378..2388814 1 NC_018650.1 COG0397 Uncharacterized conserved protein; hypothetical protein 2388814 13688791 O3M_11665 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769978.1 2387378 D 1134782 CDS YP_006769979.1 410482433 13688792 complement(2388818..2389009) 1 NC_018650.1 COG4256 Hemin uptake protein; hypothetical protein 2389009 13688792 O3M_11670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769979.1 2388818 R 1134782 CDS YP_006769980.1 410482434 13688793 complement(2389141..2390187) 1 NC_018650.1 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase 2390187 13688793 O3M_11675 Escherichia coli O104:H4 str. 2009EL-2050 phospho-2-dehydro-3-deoxyheptonate aldolase YP_006769980.1 2389141 R 1134782 CDS YP_006769981.1 410482435 13688794 complement(2390344..2391177) 1 NC_018650.1 COG1806 Uncharacterized protein conserved in bacteria; PEP synthetase regulatory protein 2391177 13688794 O3M_11680 Escherichia coli O104:H4 str. 2009EL-2050 PEP synthetase regulatory protein YP_006769981.1 2390344 R 1134782 CDS YP_006769982.1 410482436 13688795 2391510..2393888 1 NC_018650.1 COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; phosphoenolpyruvate synthase 2393888 13688795 O3M_11685 Escherichia coli O104:H4 str. 2009EL-2050 phosphoenolpyruvate synthase YP_006769982.1 2391510 D 1134782 CDS YP_006769983.1 410482437 13688796 complement(2393945..2395645) 1 NC_018650.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; short chain acyl-CoA synthetase 2395645 13688796 O3M_11690 Escherichia coli O104:H4 str. 2009EL-2050 short chain acyl-CoA synthetase YP_006769983.1 2393945 R 1134782 CDS YP_006769984.1 410482438 13688797 complement(2395648..2395941) 1 NC_018650.1 COG2440 Ferredoxin-like protein; ferredoxin-like protein FixX 2395941 13688797 O3M_11695 Escherichia coli O104:H4 str. 2009EL-2050 ferredoxin-like protein FixX YP_006769984.1 2395648 R 1134782 CDS YP_006769985.1 410482439 13688798 complement(2395938..2397227) 1 NC_018650.1 COG0644 Dehydrogenases (flavoproteins); oxidoreductase 2397227 13688798 O3M_11700 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006769985.1 2395938 R 1134782 CDS YP_006769986.1 410482440 13688799 complement(2397283..2398221) 1 NC_018650.1 COG2025 Electron transfer flavoprotein, alpha subunit; electron transfer flavoprotein subunit YdiR 2398221 13688799 O3M_11705 Escherichia coli O104:H4 str. 2009EL-2050 electron transfer flavoprotein subunit YdiR YP_006769986.1 2397283 R 1134782 CDS YP_006769987.1 410482441 13688800 complement(2398241..2399005) 1 NC_018650.1 COG2086 Electron transfer flavoprotein, beta subunit; hypothetical protein 2399005 13688800 O3M_11710 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769987.1 2398241 R 1134782 CDS YP_006769988.1 410482442 13688801 2399042..2399218 1 NC_018650.1 hypothetical protein 2399218 13688801 O3M_11715 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769988.1 2399042 D 1134782 CDS YP_006769989.1 410482443 13688802 2399321..2400232 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 2400232 13688802 O3M_11720 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006769989.1 2399321 D 1134782 CDS YP_006769990.1 410482444 13688803 complement(2400275..2401426) 1 NC_018650.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 2401426 13688803 O3M_11725 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA dehydrogenase YP_006769990.1 2400275 R 1134782 CDS YP_006769991.1 410482445 13688804 complement(2401440..2403035) 1 NC_018650.1 COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; acetyl-CoA: acetoacetyl-CoA transferase subunit alpha/beta 2403035 13688804 O3M_11730 Escherichia coli O104:H4 str. 2009EL-2050 acetyl-CoA: acetoacetyl-CoA transferase subunit alpha/beta YP_006769991.1 2401440 R 1134782 CDS YP_006769992.1 410482446 13688805 complement(2403179..2403937) 1 NC_018650.1 COG0710 3-dehydroquinate dehydratase; 3-dehydroquinate dehydratase 2403937 aroD 13688805 aroD Escherichia coli O104:H4 str. 2009EL-2050 3-dehydroquinate dehydratase YP_006769992.1 2403179 R 1134782 CDS YP_006769993.1 410482447 13688806 complement(2403968..2404834) 1 NC_018650.1 COG0169 Shikimate 5-dehydrogenase; quinate/shikimate dehydrogenase 2404834 13688806 O3M_11740 Escherichia coli O104:H4 str. 2009EL-2050 quinate/shikimate dehydrogenase YP_006769993.1 2403968 R 1134782 CDS YP_006769994.1 410482448 13688807 complement(2404846..2406111) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 2406111 13688807 O3M_11745 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769994.1 2404846 R 1134782 CDS YP_006769995.1 410482449 13688808 complement(2406338..2407552) 1 NC_018650.1 MFS superfamily protein; COG0477 Permeases of the major facilitator superfamily; transporter 2407552 13688808 O3M_11750 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006769995.1 2406338 R 1134782 CDS YP_006769996.1 410482450 13688809 complement(2407652..2408008) 1 NC_018650.1 hypothetical protein 2408008 13688809 O3M_11755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006769996.1 2407652 R 1134782 CDS YP_006769997.1 410482451 13688810 complement(2408437..2409549) 1 NC_018650.1 COG0628 Predicted permease; inner membrane protein 2409549 13688810 O3M_11760 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006769997.1 2408437 R 1134782 CDS YP_006769998.1 410482452 13688811 2409938..2412994 1 NC_018650.1 COG0277 FAD/FMN-containing dehydrogenases; FAD-linked oxidoreductase 2412994 13688811 O3M_11765 Escherichia coli O104:H4 str. 2009EL-2050 FAD-linked oxidoreductase YP_006769998.1 2409938 D 1134782 CDS YP_006769999.1 410482453 13688812 2412991..2413401 1 NC_018650.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; acyl-CoA esterase 2413401 13688812 O3M_11770 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA esterase YP_006769999.1 2412991 D 1134782 CDS YP_006770000.1 410482454 13688813 2413420..2413689 1 NC_018650.1 hypothetical protein 2413689 13688813 O3M_11775 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770000.1 2413420 D 1134782 CDS YP_006770001.1 410482455 13688814 2414238..2414606 1 NC_018650.1 COG0316 Uncharacterized conserved protein; iron-sulfur cluster assembly scaffold protein 2414606 sufA 13688814 sufA Escherichia coli O104:H4 str. 2009EL-2050 iron-sulfur cluster assembly scaffold protein YP_006770001.1 2414238 D 1134782 CDS YP_006770002.1 410482456 13688815 2414615..2416102 1 NC_018650.1 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; cysteine desulfurase activator complex subunit SufB 2416102 13688815 O3M_11785 Escherichia coli O104:H4 str. 2009EL-2050 cysteine desulfurase activator complex subunit SufB YP_006770002.1 2414615 D 1134782 CDS YP_006770003.1 410482457 13688816 2416112..2416858 1 NC_018650.1 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; cysteine desulfurase 2416858 sufC 13688816 sufC Escherichia coli O104:H4 str. 2009EL-2050 cysteine desulfurase YP_006770003.1 2416112 D 1134782 CDS YP_006770004.1 410482458 13688817 2416833..2418104 1 NC_018650.1 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; cysteine desulfurase activator complex subunit SufD 2418104 13688817 O3M_11795 Escherichia coli O104:H4 str. 2009EL-2050 cysteine desulfurase activator complex subunit SufD YP_006770004.1 2416833 D 1134782 CDS YP_006770005.1 410482459 13688818 2418101..2419321 1 NC_018650.1 COG0520 Selenocysteine lyase; bifunctional cysteine desulfurase/selenocysteine lyase 2419321 13688818 O3M_11800 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional cysteine desulfurase/selenocysteine lyase YP_006770005.1 2418101 D 1134782 CDS YP_006770006.1 410482460 13688819 2419334..2419750 1 NC_018650.1 COG2166 SufE protein probably involved in Fe-S center assembly; cysteine desufuration protein SufE 2419750 13688819 O3M_11805 Escherichia coli O104:H4 str. 2009EL-2050 cysteine desufuration protein SufE YP_006770006.1 2419334 D 1134782 CDS YP_006770007.1 410482461 13688820 2419899..2420903 1 NC_018650.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 2420903 13688820 O3M_11810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770007.1 2419899 D 1134782 CDS YP_006770008.1 410482462 13688821 complement(2420967..2421203) 1 NC_018650.1 COG4238 Murein lipoprotein; murein lipoprotein 2421203 13688821 O3M_11815 Escherichia coli O104:H4 str. 2009EL-2050 murein lipoprotein YP_006770008.1 2420967 R 1134782 CDS YP_006770009.1 410482463 13688822 complement(2421514..2422926) 1 NC_018650.1 COG0469 Pyruvate kinase; pyruvate kinase 2422926 13688822 O3M_11820 Escherichia coli O104:H4 str. 2009EL-2050 pyruvate kinase YP_006770009.1 2421514 R 1134782 CDS YP_006770010.1 410482464 13688823 2423483..2423692 1 NC_018650.1 hypothetical protein 2423692 13688823 O3M_11825 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770010.1 2423483 D 1134782 CDS YP_006770011.1 410482465 13688824 2424148..2424774 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; hypothetical protein 2424774 13688824 O3M_11830 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770011.1 2424148 D 1134782 CDS YP_006770012.1 410482466 13688825 2424795..2426897 1 NC_018650.1 COG2414 Aldehyde:ferredoxin oxidoreductase; oxidoreductase 2426897 13688825 O3M_11835 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770012.1 2424795 D 1134782 CDS YP_006770013.1 410482467 13688826 2426901..2427548 1 NC_018650.1 hypothetical protein 2427548 13688826 O3M_11840 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770013.1 2426901 D 1134782 CDS YP_006770014.1 410482468 13688827 2427561..2428280 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; oxidoreductase, Fe-S subunit 2428280 13688827 O3M_11845 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase, Fe-S subunit YP_006770014.1 2427561 D 1134782 CDS YP_006770015.1 410482469 13688828 2428277..2429062 1 NC_018650.1 thiosulfate reductase cytochrome B subunit 2429062 13688828 O3M_11850 Escherichia coli O104:H4 str. 2009EL-2050 thiosulfate reductase cytochrome B subunit YP_006770015.1 2428277 D 1134782 CDS YP_006770016.1 410482470 13688829 2429066..2429878 1 NC_018650.1 hypothetical protein 2429878 13688829 O3M_11855 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770016.1 2429066 D 1134782 CDS YP_006770017.1 410482471 13688830 complement(2429890..2431494) 1 NC_018650.1 COG4529 Uncharacterized protein conserved in bacteria; hypothetical protein 2431494 13688830 O3M_11860 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770017.1 2429890 R 1134782 CDS YP_006770018.1 410482472 13688831 complement(2431620..2431925) 1 NC_018650.1 COG0113 Delta-aminolevulinic acid dehydratase; monooxygenase 2431925 13688831 O3M_11865 Escherichia coli O104:H4 str. 2009EL-2050 monooxygenase YP_006770018.1 2431620 R 1134782 CDS YP_006770019.1 410482473 13688834 2432498..2433754 1 NC_018650.1 hypothetical protein 2433754 13688834 O3M_11870 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770019.1 2432498 D 1134782 CDS YP_006770020.1 410482474 13688835 complement(2433795..2435168) 1 NC_018650.1 COG0534 Na+-driven multidrug efflux pump; multidrug efflux protein 2435168 13688835 O3M_11875 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux protein YP_006770020.1 2433795 R 1134782 CDS YP_006770021.1 410482475 13688836 2435383..2436024 1 NC_018650.1 COG0307 Riboflavin synthase alpha chain; riboflavin synthase subunit alpha 2436024 13688836 O3M_11880 Escherichia coli O104:H4 str. 2009EL-2050 riboflavin synthase subunit alpha YP_006770021.1 2435383 D 1134782 CDS YP_006770022.1 410482476 13688837 complement(2436064..2437212) 1 NC_018650.1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane-fatty-acyl-phospholipid synthase 2437212 13688837 O3M_11885 Escherichia coli O104:H4 str. 2009EL-2050 cyclopropane-fatty-acyl-phospholipid synthase YP_006770022.1 2436064 R 1134782 CDS YP_006770023.1 410482477 13688838 complement(2437503..2438714) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 2438714 13688838 O3M_11890 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770023.1 2437503 R 1134782 CDS YP_006770024.1 410482478 13688839 2438827..2439759 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 2439759 13688839 O3M_11895 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770024.1 2438827 D 1134782 CDS YP_006770025.1 410482479 13688840 complement(2439756..2440781) 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional repressor PurR 2440781 13688840 O3M_11900 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor PurR YP_006770025.1 2439756 R 1134782 CDS YP_006770026.1 410482480 13688841 2441080..2441169 1 NC_018650.1 hypothetical protein 2441169 13688841 O3M_11905 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770026.1 2441080 D 1134782 CDS YP_006770027.1 410482481 13688842 2441335..2442504 1 NC_018650.1 COG2814 Arabinose efflux permease; transporter 2442504 13688842 O3M_11910 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770027.1 2441335 D 1134782 CDS YP_006770028.1 410482482 13688843 complement(2442650..2443231) 1 NC_018650.1 COG0605 Superoxide dismutase; superoxide dismutase 2443231 13688843 O3M_11915 Escherichia coli O104:H4 str. 2009EL-2050 superoxide dismutase YP_006770028.1 2442650 R 1134782 CDS YP_006770029.1 410482483 13688844 complement(2443359..2444174) 1 NC_018650.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); lipoprotein 2444174 13688844 O3M_11920 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770029.1 2443359 R 1134782 CDS YP_006770030.1 410482484 13688845 2444508..2444855 1 NC_018650.1 COG0278 Glutaredoxin-related protein; glutaredoxin-4 2444855 13688845 O3M_11925 Escherichia coli O104:H4 str. 2009EL-2050 glutaredoxin-4 YP_006770030.1 2444508 D 1134782 CDS YP_006770031.1 410482485 13688846 complement(2444906..2449522) 1 NC_018650.1 COG1201 Lhr-like helicases; ATP-dependent helicase Lhr 2449522 13688846 O3M_11930 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent helicase Lhr YP_006770031.1 2444906 R 1134782 CDS YP_006770032.1 410482486 13688847 complement(2449615..2450262) 1 NC_018650.1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; ribonuclease T 2450262 13688847 O3M_11935 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease T YP_006770032.1 2449615 R 1134782 CDS YP_006770033.1 410482487 13688848 complement(2450365..2450772) 1 NC_018650.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase I 2450772 13688848 O3M_11940 Escherichia coli O104:H4 str. 2009EL-2050 glyoxalase I YP_006770033.1 2450365 R 1134782 CDS YP_006770034.1 410482488 13688849 complement(2450853..2451950) 1 NC_018650.1 COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; N-ethylmaleimide reductase 2451950 13688849 O3M_11945 Escherichia coli O104:H4 str. 2009EL-2050 N-ethylmaleimide reductase YP_006770034.1 2450853 R 1134782 CDS YP_006770035.1 410482489 13688850 complement(2451987..2452586) 1 NC_018650.1 COG1309 Transcriptional regulator; DNA-binding transcriptional regulator 2452586 13688850 O3M_11950 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770035.1 2451987 R 1134782 CDS YP_006770036.1 410482490 13688851 2452518..2452928 1 NC_018650.1 COG3313 Predicted Fe-S protein; hypothetical protein 2452928 13688851 O3M_11955 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770036.1 2452518 D 1134782 CDS YP_006770037.1 410482491 13688852 2452977..2453873 1 NC_018650.1 COG4989 Predicted oxidoreductase; oxidoreductase 2453873 13688852 O3M_11960 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770037.1 2452977 D 1134782 CDS YP_006770038.1 410482492 13688853 2453954..2454475 1 NC_018650.1 COG2032 Cu/Zn superoxide dismutase; superoxide dismutase 2454475 13688853 O3M_11965 Escherichia coli O104:H4 str. 2009EL-2050 superoxide dismutase YP_006770038.1 2453954 D 1134782 CDS YP_006770039.1 410482493 13688854 complement(2454476..2456488) 1 NC_018650.1 COG1289 Predicted membrane protein; hypothetical protein 2456488 13688854 O3M_11970 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770039.1 2454476 R 1134782 CDS YP_006770040.1 410482494 13688855 complement(2456488..2457345) 1 NC_018650.1 COG1566 Multidrug resistance efflux pump; undecaprenyl pyrophosphate phosphatase 2457345 13688855 O3M_11975 Escherichia coli O104:H4 str. 2009EL-2050 undecaprenyl pyrophosphate phosphatase YP_006770040.1 2456488 R 1134782 CDS YP_006770041.1 410482495 13688856 complement(2457348..2457584) 1 NC_018650.1 hypothetical protein 2457584 13688856 O3M_11980 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770041.1 2457348 R 1134782 CDS YP_006770042.1 410482496 13688857 2457785..2458219 1 NC_018650.1 COG1846 Transcriptional regulators; transcriptional regulator SlyA 2458219 13688857 O3M_11985 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator SlyA YP_006770042.1 2457785 D 1134782 CDS YP_006770043.1 410482497 13688858 complement(2458266..2458733) 1 NC_018650.1 COG3133 Outer membrane lipoprotein; outer membrane lipoprotein SlyB 2458733 13688858 O3M_11990 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein SlyB YP_006770043.1 2458266 R 1134782 CDS YP_006770044.1 410482498 13688859 2459007..2460116 1 NC_018650.1 COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases; anhydro-N-acetylmuramic acid kinase 2460116 anmK 13688859 anmK Escherichia coli O104:H4 str. 2009EL-2050 anhydro-N-acetylmuramic acid kinase YP_006770044.1 2459007 D 1134782 CDS YP_006770045.1 410482499 13688860 2460214..2460543 1 NC_018650.1 COG3895 Predicted periplasmic protein; lysozyme inhibitor 2460543 13688860 O3M_12000 Escherichia coli O104:H4 str. 2009EL-2050 lysozyme inhibitor YP_006770045.1 2460214 D 1134782 CDS YP_006770046.1 410482500 13688861 2460602..2461258 1 NC_018650.1 COG0259 Pyridoxamine-phosphate oxidase; pyridoxamine 5'-phosphate oxidase 2461258 13688861 O3M_12005 Escherichia coli O104:H4 str. 2009EL-2050 pyridoxamine 5'-phosphate oxidase YP_006770046.1 2460602 D 1134782 CDS YP_006770047.1 410482501 13688862 2461387..2462661 1 NC_018650.1 COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 2462661 13688862 O3M_12010 Escherichia coli O104:H4 str. 2009EL-2050 tyrosyl-tRNA synthetase YP_006770047.1 2461387 D 1134782 CDS YP_006770048.1 410482502 13688863 2462723..2463583 1 NC_018650.1 COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxamine kinase 2463583 13688863 O3M_12015 Escherichia coli O104:H4 str. 2009EL-2050 pyridoxamine kinase YP_006770048.1 2462723 D 1134782 CDS YP_006770049.1 410482503 13688864 complement(2463627..2464232) 1 NC_018650.1 COG0625 Glutathione S-transferase; glutathionine S-transferase 2464232 13688864 O3M_12020 Escherichia coli O104:H4 str. 2009EL-2050 glutathionine S-transferase YP_006770049.1 2463627 R 1134782 CDS YP_006770050.1 410482504 13688865 complement(2464338..2465840) 1 NC_018650.1 COG3104 Dipeptide/tripeptide permease; tripeptide transporter permease 2465840 tppB 13688865 tppB Escherichia coli O104:H4 str. 2009EL-2050 tripeptide transporter permease YP_006770050.1 2464338 R 1134782 CDS YP_006770051.1 410482505 13688866 complement(2466123..2466323) 1 NC_018650.1 hypothetical protein 2466323 13688866 O3M_12030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770051.1 2466123 R 1134782 CDS YP_006770052.1 410482506 13688867 complement(2466451..2467086) 1 NC_018650.1 COG0177 Predicted EndoIII-related endonuclease; endonuclease III 2467086 13688867 O3M_12035 Escherichia coli O104:H4 str. 2009EL-2050 endonuclease III YP_006770052.1 2466451 R 1134782 CDS YP_006770053.1 410482507 13688868 complement(2467086..2467781) 1 NC_018650.1 COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE; electron transport complex protein RsxE 2467781 13688868 O3M_12040 Escherichia coli O104:H4 str. 2009EL-2050 electron transport complex protein RsxE YP_006770053.1 2467086 R 1134782 CDS YP_006770054.1 410482508 13688869 complement(2467785..2468405) 1 NC_018650.1 COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG; electron transport complex protein RnfG 2468405 13688869 O3M_12045 Escherichia coli O104:H4 str. 2009EL-2050 electron transport complex protein RnfG YP_006770054.1 2467785 R 1134782 CDS YP_006770055.1 410482509 13688870 complement(2468409..2469467) 1 NC_018650.1 COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD; electron transport complex protein RnfD 2469467 rnfD 13688870 rnfD Escherichia coli O104:H4 str. 2009EL-2050 electron transport complex protein RnfD YP_006770055.1 2468409 R 1134782 CDS YP_006770056.1 410482510 13688871 complement(2469468..2471594) 1 NC_018650.1 COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC; electron transport complex protein RnfC 2471594 13688871 O3M_12055 Escherichia coli O104:H4 str. 2009EL-2050 electron transport complex protein RnfC YP_006770056.1 2469468 R 1134782 CDS YP_006770057.1 410482511 13688872 complement(2471587..2472165) 1 NC_018650.1 COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB; electron transport complex protein RnfB 2472165 13688872 O3M_12060 Escherichia coli O104:H4 str. 2009EL-2050 electron transport complex protein RnfB YP_006770057.1 2471587 R 1134782 CDS YP_006770058.1 410482512 13688873 complement(2472165..2472746) 1 NC_018650.1 COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA; electron transport complex protein RsxA 2472746 13688873 O3M_12065 Escherichia coli O104:H4 str. 2009EL-2050 electron transport complex protein RsxA YP_006770058.1 2472165 R 1134782 CDS YP_006770059.1 410482513 13688874 complement(2472823..2473263) 1 NC_018650.1 hypothetical protein 2473263 13688874 O3M_12070 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770059.1 2472823 R 1134782 CDS YP_006770060.1 410482514 13688875 complement(2473349..2473564) 1 NC_018650.1 oriC-binding nucleoid-associated protein 2473564 13688875 O3M_12075 Escherichia coli O104:H4 str. 2009EL-2050 oriC-binding nucleoid-associated protein YP_006770060.1 2473349 R 1134782 CDS YP_006770061.1 410482515 13688876 2474205..2475245 1 NC_018650.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 2475245 13688876 O3M_12080 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770061.1 2474205 D 1134782 CDS YP_006770062.1 410482516 13688877 complement(2475280..2476281) 1 NC_018650.1 COG1816 Adenosine deaminase; adenosine deaminase 2476281 13688877 O3M_12085 Escherichia coli O104:H4 str. 2009EL-2050 adenosine deaminase YP_006770062.1 2475280 R 1134782 CDS YP_006770063.1 410482517 13688878 complement(2476385..2477557) 1 NC_018650.1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; bifunctional beta-cystathionase and regulator of maltose regulon 2477557 13688878 O3M_12090 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional beta-cystathionase and regulator of maltose regulon YP_006770063.1 2476385 R 1134782 CDS YP_006770064.1 410482518 13688879 complement(2477567..2479159) 1 NC_018650.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system maltose and glucose-specific transporter subunits IICB 2479159 13688879 O3M_12095 Escherichia coli O104:H4 str. 2009EL-2050 PTS system maltose and glucose-specific transporter subunits IICB YP_006770064.1 2477567 R 1134782 CDS YP_006770065.1 410482519 13688880 2479334..2480362 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional repressor MalI 2480362 13688880 O3M_12100 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor MalI YP_006770065.1 2479334 D 1134782 CDS YP_006770066.1 410482520 13688881 2480474..2481241 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 7-alpha-hydroxysteroid dehydrogenase 2481241 13688881 O3M_12105 Escherichia coli O104:H4 str. 2009EL-2050 7-alpha-hydroxysteroid dehydrogenase YP_006770066.1 2480474 D 1134782 CDS YP_006770067.1 410482521 13688882 2481470..2482060 1 NC_018650.1 COG1309 Transcriptional regulator; DNA-binding transcriptional repressor UidR 2482060 13688882 O3M_12110 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor UidR YP_006770067.1 2481470 D 1134782 CDS YP_006770068.1 410482522 13688883 2482449..2484260 1 NC_018650.1 COG3250 Beta-galactosidase/beta-glucuronidase; beta-D-glucuronidase 2484260 13688883 O3M_12115 Escherichia coli O104:H4 str. 2009EL-2050 beta-D-glucuronidase YP_006770068.1 2482449 D 1134782 CDS YP_006770069.1 410482523 13688884 2484257..2485630 1 NC_018650.1 COG2211 Na+/melibiose symporter and related transporters; glucuronide transporter 2485630 13688884 O3M_12120 Escherichia coli O104:H4 str. 2009EL-2050 glucuronide transporter YP_006770069.1 2484257 D 1134782 CDS YP_006770070.1 410482524 13688885 2485669..2486934 1 NC_018650.1 outer membrane porin protein 2486934 13688885 O3M_12125 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane porin protein YP_006770070.1 2485669 D 1134782 CDS YP_006770071.1 410482525 13688886 complement(2486979..2488487) 1 NC_018650.1 COG5339 Uncharacterized protein conserved in bacteria; hypothetical protein 2488487 13688886 O3M_12130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770071.1 2486979 R 1134782 CDS YP_006770072.1 410482526 13688887 complement(2488588..2489763) 1 NC_018650.1 COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase 2489763 13688887 O3M_12135 Escherichia coli O104:H4 str. 2009EL-2050 mannose-6-phosphate isomerase YP_006770072.1 2488588 R 1134782 CDS YP_006770073.1 410482527 13688888 2489962..2491608 1 NC_018650.1 COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase FumA 2491608 13688888 O3M_12140 Escherichia coli O104:H4 str. 2009EL-2050 fumarate hydratase FumA YP_006770073.1 2489962 D 1134782 CDS YP_006770074.1 410482528 13688889 2491751..2493154 1 NC_018650.1 COG0114 Fumarase; fumarate hydratase 2493154 fumC 13688889 fumC Escherichia coli O104:H4 str. 2009EL-2050 fumarate hydratase YP_006770074.1 2491751 D 1134782 CDS YP_006770075.1 410482529 13688890 complement(2493151..2494080) 1 NC_018650.1 DNA replication terminus site-binding protein 2494080 13688890 O3M_12150 Escherichia coli O104:H4 str. 2009EL-2050 DNA replication terminus site-binding protein YP_006770075.1 2493151 R 1134782 CDS YP_006770076.1 410482530 13688891 complement(2494156..2495457) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor protein RstB 2495457 13688891 O3M_12155 Escherichia coli O104:H4 str. 2009EL-2050 sensor protein RstB YP_006770076.1 2494156 R 1134782 CDS YP_006770077.1 410482531 13688892 complement(2495461..2496180) 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator RstA 2496180 13688892 O3M_12160 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator RstA YP_006770077.1 2495461 R 1134782 CDS YP_006770078.1 410482532 13688893 2496309..2496644 1 NC_018650.1 COG3136 Uncharacterized membrane protein required for alginate biosynthesis; GlpM family protein 2496644 13688893 O3M_12165 Escherichia coli O104:H4 str. 2009EL-2050 GlpM family protein YP_006770078.1 2496309 D 1134782 CDS YP_006770079.1 410482533 13688894 complement(2496641..2497363) 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dihydromonapterin reductase 2497363 13688894 O3M_12170 Escherichia coli O104:H4 str. 2009EL-2050 dihydromonapterin reductase YP_006770079.1 2496641 R 1134782 CDS YP_006770080.1 410482534 13688895 complement(2497400..2498782) 1 NC_018650.1 COG0531 Amino acid transporters; arginine/ornithine antiporter 2498782 13688895 O3M_12175 Escherichia coli O104:H4 str. 2009EL-2050 arginine/ornithine antiporter YP_006770080.1 2497400 R 1134782 CDS YP_006770081.1 410482535 13688896 complement(2498968..2499912) 1 NC_018650.1 hypothetical protein 2499912 13688896 O3M_12180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770081.1 2498968 R 1134782 CDS YP_006770082.1 410482536 13688897 2500436..2501968 1 NC_018650.1 COG3288 NAD/NADP transhydrogenase alpha subunit; NAD(P) transhydrogenase subunit alpha 2501968 pntA 13688897 pntA Escherichia coli O104:H4 str. 2009EL-2050 NAD(P) transhydrogenase subunit alpha YP_006770082.1 2500436 D 1134782 CDS YP_006770083.1 410482537 13688898 2501979..2503367 1 NC_018650.1 COG1282 NAD/NADP transhydrogenase beta subunit; pyridine nucleotide transhydrogenase 2503367 pntB 13688898 pntB Escherichia coli O104:H4 str. 2009EL-2050 pyridine nucleotide transhydrogenase YP_006770083.1 2501979 D 1134782 CDS YP_006770084.1 410482538 13688899 complement(2503392..2504426) 1 NC_018650.1 COG0628 Predicted permease; pheromone autoinducer 2 transporter 2504426 tqsA 13688899 tqsA Escherichia coli O104:H4 str. 2009EL-2050 pheromone autoinducer 2 transporter YP_006770084.1 2503392 R 1134782 CDS YP_006770085.1 410482539 13688900 2504838..2505203 1 NC_018650.1 COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux system protein MdtJ 2505203 13688900 O3M_12200 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein MdtJ YP_006770085.1 2504838 D 1134782 CDS YP_006770086.1 410482540 13688901 2505190..2505519 1 NC_018650.1 COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux system protein MdtI 2505519 13688901 O3M_12205 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein MdtI YP_006770086.1 2505190 D 1134782 CDS YP_006770087.1 410482541 13688902 complement(2505558..2506379) 1 NC_018650.1 COG3591 V8-like Glu-specific endopeptidase; metallopeptidase 2506379 13688902 O3M_12210 Escherichia coli O104:H4 str. 2009EL-2050 metallopeptidase YP_006770087.1 2505558 R 1134782 CDS YP_006770088.1 410482542 13688903 complement(2506479..2506562) 1 NC_018650.1 hypothetical protein 2506562 13688903 O3M_12215 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770088.1 2506479 R 1134782 CDS YP_006770089.1 410482543 13688904 complement(2506655..2506963) 1 NC_018650.1 acid shock protein 2506963 13688904 O3M_12220 Escherichia coli O104:H4 str. 2009EL-2050 acid shock protein YP_006770089.1 2506655 R 1134782 CDS YP_006770090.1 410482544 13688905 complement(2507387..2508640) 1 NC_018650.1 MFS type; COG0477 Permeases of the major facilitator superfamily; transporter 2508640 13688905 O3M_12225 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770090.1 2507387 R 1134782 CDS YP_006770091.1 410482545 13688906 2508747..2509640 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 2509640 13688906 O3M_12230 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770091.1 2508747 D 1134782 CDS YP_006770092.1 410482546 13688907 2509775..2510995 1 NC_018650.1 COG1940 Transcriptional regulator/sugar kinase; NAGC-like transcriptional regulator 2510995 13688907 O3M_12235 Escherichia coli O104:H4 str. 2009EL-2050 NAGC-like transcriptional regulator YP_006770092.1 2509775 D 1134782 CDS YP_006770093.1 410482547 13688908 2511120..2511815 1 NC_018650.1 COG0132 Dethiobiotin synthetase; dithiobiotin synthetase 2511815 13688908 O3M_12240 Escherichia coli O104:H4 str. 2009EL-2050 dithiobiotin synthetase YP_006770093.1 2511120 D 1134782 CDS YP_006770094.1 410482548 13688909 complement(2511831..2513024) 1 NC_018650.1 COG0038 Chloride channel protein EriC; voltage-gated ClC-type chloride channel ClcB 2513024 13688909 O3M_12245 Escherichia coli O104:H4 str. 2009EL-2050 voltage-gated ClC-type chloride channel ClcB YP_006770094.1 2511831 R 1134782 CDS YP_006770095.1 410482549 13688910 complement(2513219..2513833) 1 NC_018650.1 COG3381 Uncharacterized component of anaerobic dehydrogenases; twin-argninine leader-binding protein DmsD 2513833 13688910 O3M_12250 Escherichia coli O104:H4 str. 2009EL-2050 twin-argninine leader-binding protein DmsD YP_006770095.1 2513219 R 1134782 CDS YP_006770096.1 410482550 13688911 complement(2513876..2514730) 1 NC_018650.1 COG3302 DMSO reductase anchor subunit; oxidoreductase, membrane subunit 2514730 13688911 O3M_12255 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase, membrane subunit YP_006770096.1 2513876 R 1134782 CDS YP_006770097.1 410482551 13688912 complement(2514732..2515283) 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; anaerobic dimethyl sulfoxide reductase subunit ynfG 2515283 13688912 O3M_12260 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic dimethyl sulfoxide reductase subunit ynfG YP_006770097.1 2514732 R 1134782 CDS YP_006770098.1 410482552 13688913 complement(2515324..2516487) 1 NC_018650.1 COG0582 Integrase; prophage DLP12 integrase 2516487 13688913 O3M_12265 Escherichia coli O104:H4 str. 2009EL-2050 prophage DLP12 integrase YP_006770098.1 2515324 R 1134782 CDS YP_006770099.1 410482553 13688914 complement(2516343..2516714) 1 NC_018650.1 COG2452 Predicted site-specific integrase-resolvase; excisionase 2516714 13688914 O3M_12270 Escherichia coli O104:H4 str. 2009EL-2050 excisionase YP_006770099.1 2516343 R 1134782 CDS YP_006770100.1 410482554 13688915 complement(2516749..2517000) 1 NC_018650.1 hypothetical protein 2517000 13688915 O3M_12275 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770100.1 2516749 R 1134782 CDS YP_006770101.1 410482555 13688916 complement(2517048..2517728) 1 NC_018650.1 exonuclease 2517728 13688916 O3M_12280 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease YP_006770101.1 2517048 R 1134782 CDS YP_006770102.1 410482556 13688917 complement(2517725..2518510) 1 NC_018650.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Recombination protein bet from phage origin 2518510 13688917 O3M_12285 Escherichia coli O104:H4 str. 2009EL-2050 Recombination protein bet from phage origin YP_006770102.1 2517725 R 1134782 CDS YP_006770103.1 410482557 13688918 complement(2518516..2518812) 1 NC_018650.1 host-nuclease inhibitor protein Gam of bacteriophage 2518812 13688918 O3M_12290 Escherichia coli O104:H4 str. 2009EL-2050 host-nuclease inhibitor protein Gam of bacteriophage YP_006770103.1 2518516 R 1134782 CDS YP_006770104.1 410482558 13688919 complement(2520989..2521375) 1 NC_018650.1 hypothetical protein 2521375 13688919 O3M_12300 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770104.1 2520989 R 1134782 CDS YP_006770105.1 410482559 13688920 complement(2521459..2521680) 1 NC_018650.1 FtsZ inhibitor protein 2521680 kil 13688920 kil Escherichia coli O104:H4 str. 2009EL-2050 FtsZ inhibitor protein YP_006770105.1 2521459 R 1134782 CDS YP_006770106.1 410482560 13688921 2522137..2522346 1 NC_018650.1 hypothetical protein 2522346 13688921 O3M_12310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770106.1 2522137 D 1134782 CDS YP_006770107.1 410482561 13688922 complement(2522315..2522674) 1 NC_018650.1 hypothetical protein 2522674 13688922 O3M_12315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770107.1 2522315 R 1134782 CDS YP_006770108.1 410482562 13688923 complement(2522706..2523419) 1 NC_018650.1 hypothetical protein 2523419 13688923 O3M_12320 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770108.1 2522706 R 1134782 CDS YP_006770109.1 410482563 13688924 complement(2523423..2523806) 1 NC_018650.1 Antitermination protein N 2523806 13688924 O3M_12325 Escherichia coli O104:H4 str. 2009EL-2050 Antitermination protein N YP_006770109.1 2523423 R 1134782 CDS YP_006770110.1 410482564 13688925 complement(2524301..2525077) 1 NC_018650.1 hypothetical protein 2525077 13688925 O3M_12330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770110.1 2524301 R 1134782 CDS YP_006770111.1 410482565 13688926 complement(2525065..2525607) 1 NC_018650.1 hypothetical protein 2525607 13688926 O3M_12335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770111.1 2525065 R 1134782 CDS YP_006770112.1 410482566 13688927 complement(2525654..2526367) 1 NC_018650.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Repressor protein CI from prophage 2526367 13688927 O3M_12340 Escherichia coli O104:H4 str. 2009EL-2050 Repressor protein CI from prophage YP_006770112.1 2525654 R 1134782 CDS YP_006770113.1 410482567 13688928 2526468..2526668 1 NC_018650.1 regulatory protein cro 2526668 13688928 O3M_12345 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein cro YP_006770113.1 2526468 D 1134782 CDS YP_006770114.1 410482568 13688929 2526807..2527103 1 NC_018650.1 regulatory protein CII from prophage 2527103 13688929 O3M_12350 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein CII from prophage YP_006770114.1 2526807 D 1134782 CDS YP_006770115.1 410482569 13688930 2527118..2527336 1 NC_018650.1 hypothetical protein 2527336 13688930 O3M_12355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770115.1 2527118 D 1134782 CDS YP_006770116.1 410482570 13688931 2527438..2528439 1 NC_018650.1 hypothetical protein 2528439 13688931 O3M_12360 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770116.1 2527438 D 1134782 CDS YP_006770117.1 410482571 13688932 2528446..2529186 1 NC_018650.1 COG1484 DNA replication protein; replication protein 2529186 13688932 O3M_12365 Escherichia coli O104:H4 str. 2009EL-2050 replication protein YP_006770117.1 2528446 D 1134782 CDS YP_006770118.1 410482572 13688933 2529212..2529982 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; hypothetical protein 2529982 13688933 O3M_12370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770118.1 2529212 D 1134782 CDS YP_006770119.1 410482573 13688934 2529998..2530393 1 NC_018650.1 hypothetical protein 2530393 13688934 O3M_12375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770119.1 2529998 D 1134782 CDS YP_006770120.1 410482574 13688935 2530450..2531034 1 NC_018650.1 hypothetical protein 2531034 13688935 O3M_12380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770120.1 2530450 D 1134782 CDS YP_006770121.1 410482575 13688936 2531150..2531254 1 NC_018650.1 hypothetical protein 2531254 13688936 O3M_12385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770121.1 2531150 D 1134782 CDS YP_006770122.1 410482576 13688937 2531443..2531655 1 NC_018650.1 cell killing protein encoded within cryptic prophage CP-933P 2531655 13688937 O3M_12390 Escherichia coli O104:H4 str. 2009EL-2050 cell killing protein encoded within cryptic prophage CP-933P YP_006770122.1 2531443 D 1134782 CDS YP_006770123.1 410482577 13688938 2531865..2532044 1 NC_018650.1 bacteriophage protein 2532044 13688938 O3M_12395 Escherichia coli O104:H4 str. 2009EL-2050 bacteriophage protein YP_006770123.1 2531865 D 1134782 CDS YP_006770124.1 410482578 13688939 2532063..2532548 1 NC_018650.1 COG3654 Prophage maintenance system killer protein; bacteriophage protein 2532548 13688939 O3M_12400 Escherichia coli O104:H4 str. 2009EL-2050 bacteriophage protein YP_006770124.1 2532063 D 1134782 CDS YP_006770125.1 410482579 13688940 complement(2532599..2532916) 1 NC_018650.1 COG2944 Predicted transcriptional regulator; DNA-binding protein 2532916 13688940 O3M_12405 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding protein YP_006770125.1 2532599 R 1134782 CDS YP_006770126.1 410482580 13688941 complement(2533024..2533278) 1 NC_018650.1 COG4737 Uncharacterized protein conserved in bacteria; hypothetical protein 2533278 13688941 O3M_12410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770126.1 2533024 R 1134782 CDS YP_006770127.1 410482581 13688942 2533623..2534294 1 NC_018650.1 antirepressor protein Ant from prophage 2534294 13688942 O3M_12415 Escherichia coli O104:H4 str. 2009EL-2050 antirepressor protein Ant from prophage YP_006770127.1 2533623 D 1134782 CDS YP_006770128.1 410482582 13688943 2534349..2534759 1 NC_018650.1 ninB protein 2534759 13688943 O3M_12420 Escherichia coli O104:H4 str. 2009EL-2050 ninB protein YP_006770128.1 2534349 D 1134782 CDS YP_006770129.1 410482583 13688944 2534756..2534947 1 NC_018650.1 NinE protein 2534947 13688944 O3M_12425 Escherichia coli O104:H4 str. 2009EL-2050 NinE protein YP_006770129.1 2534756 D 1134782 CDS YP_006770130.1 410482584 13688945 2534971..2535261 1 NC_018650.1 hypothetical protein 2535261 13688945 O3M_12430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770130.1 2534971 D 1134782 CDS YP_006770131.1 410482585 13688946 2535258..2535620 1 NC_018650.1 COG4570 Holliday junction resolvase; crossover junction endodeoxyribonuclease 2535620 13688946 O3M_12435 Escherichia coli O104:H4 str. 2009EL-2050 crossover junction endodeoxyribonuclease YP_006770131.1 2535258 D 1134782 CDS YP_006770132.1 410482586 13688947 2535620..2535814 1 NC_018650.1 Protein ninH from prophage 2535814 13688947 O3M_12440 Escherichia coli O104:H4 str. 2009EL-2050 Protein ninH from prophage YP_006770132.1 2535620 D 1134782 CDS YP_006770133.1 410482587 13688948 2535807..2536241 1 NC_018650.1 antitermination protein Q 2536241 13688948 O3M_12445 Escherichia coli O104:H4 str. 2009EL-2050 antitermination protein Q YP_006770133.1 2535807 D 1134782 CDS YP_006770134.1 410482588 13688949 2537007..2538917 1 NC_018650.1 hypothetical protein 2538917 13688949 O3M_12450 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770134.1 2537007 D 1134782 CDS YP_006770135.1 410482589 13688950 2539056..2539238 1 NC_018650.1 hypothetical protein 2539238 13688950 O3M_12455 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770135.1 2539056 D 1134782 CDS YP_006770136.1 410482590 13688951 2539264..2539509 1 NC_018650.1 hypothetical protein 2539509 13688951 O3M_12460 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770136.1 2539264 D 1134782 CDS YP_006770137.1 410482591 13688952 2539586..2539801 1 NC_018650.1 lysis protein S of prophage CP-933V 2539801 13688952 O3M_12465 Escherichia coli O104:H4 str. 2009EL-2050 lysis protein S of prophage CP-933V YP_006770137.1 2539586 D 1134782 CDS YP_006770138.1 410482592 13688953 2539806..2540339 1 NC_018650.1 COG3772 Phage-related lysozyme (muraminidase); endolysin 2540339 13688953 O3M_12470 Escherichia coli O104:H4 str. 2009EL-2050 endolysin YP_006770138.1 2539806 D 1134782 CDS YP_006770139.1 410482593 13688954 2540560..2540673 1 NC_018650.1 hypothetical protein 2540673 13688954 O3M_12475 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770139.1 2540560 D 1134782 CDS YP_006770140.1 410482594 13688955 2540675..2541133 1 NC_018650.1 endopeptidase 2541133 13688955 O3M_12480 Escherichia coli O104:H4 str. 2009EL-2050 endopeptidase YP_006770140.1 2540675 D 1134782 CDS YP_006770141.1 410482595 13688956 complement(2541214..2541795) 1 NC_018650.1 lipopolysaccharide core heptose(II)-phosphate phosphatase 2541795 13688956 O3M_12485 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide core heptose(II)-phosphate phosphatase YP_006770141.1 2541214 R 1134782 CDS YP_006770142.1 410482596 13688957 2542398..2543213 1 NC_018650.1 small subunit terminase 2543213 13688957 O3M_12490 Escherichia coli O104:H4 str. 2009EL-2050 small subunit terminase YP_006770142.1 2542398 D 1134782 CDS YP_006770143.1 410482597 13688958 2543194..2544900 1 NC_018650.1 large subunit terminase 2544900 13688958 O3M_12495 Escherichia coli O104:H4 str. 2009EL-2050 large subunit terminase YP_006770143.1 2543194 D 1134782 CDS YP_006770144.1 410482598 13688959 2544900..2547044 1 NC_018650.1 portal protein 2547044 13688959 O3M_12500 Escherichia coli O104:H4 str. 2009EL-2050 portal protein YP_006770144.1 2544900 D 1134782 CDS YP_006770145.1 410482599 13688960 2547202..2548209 1 NC_018650.1 COG0061 Predicted sugar kinase; hypothetical protein 2548209 13688960 O3M_12505 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770145.1 2547202 D 1134782 CDS YP_006770146.1 410482600 13688961 2548232..2549446 1 NC_018650.1 hypothetical protein 2549446 13688961 O3M_12510 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770146.1 2548232 D 1134782 CDS YP_006770147.1 410482601 13688962 2549501..2549890 1 NC_018650.1 hypothetical protein 2549890 13688962 O3M_12515 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770147.1 2549501 D 1134782 CDS YP_006770148.1 410482602 13688963 2549941..2550402 1 NC_018650.1 hypothetical protein 2550402 13688963 O3M_12520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770148.1 2549941 D 1134782 CDS YP_006770149.1 410482603 13688964 2550386..2550949 1 NC_018650.1 hypothetical protein 2550949 13688964 O3M_12525 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770149.1 2550386 D 1134782 CDS YP_006770150.1 410482604 13688965 2550949..2551599 1 NC_018650.1 hypothetical protein 2551599 13688965 O3M_12530 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770150.1 2550949 D 1134782 CDS YP_006770151.1 410482605 13688966 2551596..2553503 1 NC_018650.1 tail fiber protein 2553503 13688966 O3M_12535 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber protein YP_006770151.1 2551596 D 1134782 CDS YP_006770152.1 410482606 13688967 2554712..2556337 1 NC_018650.1 hypothetical protein 2556337 13688967 O3M_12540 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770152.1 2554712 D 1134782 CDS YP_006770153.1 410482607 13688968 2556334..2557602 1 NC_018650.1 COG4733 Phage-related protein, tail component; tail tip fiber protein 2557602 13688968 O3M_12545 Escherichia coli O104:H4 str. 2009EL-2050 tail tip fiber protein YP_006770153.1 2556334 D 1134782 CDS YP_006770154.1 410482608 13688969 2557617..2557895 1 NC_018650.1 outer membrane protein 2557895 13688969 O3M_12550 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein YP_006770154.1 2557617 D 1134782 CDS YP_006770155.1 410482609 13688970 2557901..2558518 1 NC_018650.1 hypothetical protein 2558518 13688970 O3M_12555 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770155.1 2557901 D 1134782 CDS YP_006770156.1 410482610 13688971 2558598..2559335 1 NC_018650.1 outer membrane precursor Lom 2559335 13688971 O3M_12560 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane precursor Lom YP_006770156.1 2558598 D 1134782 CDS YP_006770157.1 410482611 13688972 2559570..2559710 1 NC_018650.1 hypothetical protein 2559710 13688972 O3M_12565 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770157.1 2559570 D 1134782 CDS YP_006770158.1 410482612 13688973 2559767..2560168 1 NC_018650.1 hypothetical protein 2560168 13688973 O3M_12570 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770158.1 2559767 D 1134782 CDS YP_006770159.1 410482613 13688974 2560260..2560916 1 NC_018650.1 hypothetical protein 2560916 13688974 O3M_12575 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770159.1 2560260 D 1134782 CDS YP_006770160.1 410482614 13688975 2560919..2561365 1 NC_018650.1 hypothetical protein 2561365 13688975 O3M_12580 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770160.1 2560919 D 1134782 CDS YP_006770161.1 410482615 13688976 2561375..2561626 1 NC_018650.1 hypothetical protein 2561626 13688976 O3M_12585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770161.1 2561375 D 1134782 CDS YP_006770162.1 410482616 13688977 2561637..2562902 1 NC_018650.1 hypothetical protein 2562902 13688977 O3M_12590 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770162.1 2561637 D 1134782 CDS YP_006770163.1 410482617 13688978 2562971..2571322 1 NC_018650.1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); hypothetical protein 2571322 13688978 O3M_12595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770163.1 2562971 D 1134782 CDS YP_006770164.1 410482618 13688979 2571446..2571721 1 NC_018650.1 hypothetical protein 2571721 13688979 O3M_12600 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770164.1 2571446 D 1134782 CDS YP_006770165.1 410482619 13688980 complement(2571723..2572226) 1 NC_018650.1 hypothetical protein 2572226 13688980 O3M_12605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770165.1 2571723 R 1134782 CDS YP_006770166.1 410482620 13688981 complement(2572223..2572738) 1 NC_018650.1 hypothetical protein 2572738 13688981 O3M_12610 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770166.1 2572223 R 1134782 CDS YP_006770167.1 410482621 13688982 complement(2572740..2573576) 1 NC_018650.1 hypothetical protein 2573576 13688982 O3M_12615 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770167.1 2572740 R 1134782 CDS YP_006770168.1 410482622 13688983 complement(2573563..2573847) 1 NC_018650.1 hypothetical protein 2573847 13688983 O3M_12620 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770168.1 2573563 R 1134782 CDS YP_006770169.1 410482623 13688984 complement(2573844..2574065) 1 NC_018650.1 COG1734 DnaK suppressor protein; C4-type zinc finger protein 2574065 13688984 O3M_12625 Escherichia coli O104:H4 str. 2009EL-2050 C4-type zinc finger protein YP_006770169.1 2573844 R 1134782 CDS YP_006770170.1 410482624 13688985 complement(2574113..2574748) 1 NC_018650.1 COG3561 Phage anti-repressor protein; phage anti-repressor protein AntB 2574748 13688985 O3M_12630 Escherichia coli O104:H4 str. 2009EL-2050 phage anti-repressor protein AntB YP_006770170.1 2574113 R 1134782 CDS YP_006770171.1 410482625 13688986 complement(2575156..2575269) 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; dimethyl sulfoxide reductase subunit B 2575269 13688986 O3M_12635 Escherichia coli O104:H4 str. 2009EL-2050 dimethyl sulfoxide reductase subunit B YP_006770171.1 2575156 R 1134782 CDS YP_006770172.1 410482626 13688987 complement(2575280..2577703) 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase subunit 2577703 13688987 O3M_12640 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase subunit YP_006770172.1 2575280 R 1134782 CDS YP_006770173.1 410482627 13688988 complement(2577764..2580190) 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase subunit 2580190 13688988 O3M_12645 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase subunit YP_006770173.1 2577764 R 1134782 CDS YP_006770174.1 410482628 13688989 complement(2580389..2580694) 1 NC_018650.1 hypothetical protein 2580694 13688989 O3M_12650 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770174.1 2580389 R 1134782 CDS YP_006770175.1 410482629 13688990 2580802..2581512 1 NC_018650.1 lipoprotein 2581512 13688990 O3M_12655 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770175.1 2580802 D 1134782 CDS YP_006770176.1 410482630 13688991 complement(2581515..2582075) 1 NC_018650.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; spermidine N1-acetyltransferase 2582075 13688991 O3M_12660 Escherichia coli O104:H4 str. 2009EL-2050 spermidine N1-acetyltransferase YP_006770176.1 2581515 R 1134782 CDS YP_006770177.1 410482631 13688992 complement(2582110..2582451) 1 NC_018650.1 hypothetical protein 2582451 13688992 O3M_12665 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770177.1 2582110 R 1134782 CDS YP_006770178.1 410482632 13688993 2582586..2582912 1 NC_018650.1 COG1742 Uncharacterized conserved protein; hypothetical protein 2582912 13688993 O3M_12670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770178.1 2582586 D 1134782 CDS YP_006770179.1 410482633 13688994 2583118..2584332 1 NC_018650.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; bifunctional D-altronate/D-mannonate dehydratase 2584332 13688994 O3M_12675 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional D-altronate/D-mannonate dehydratase YP_006770179.1 2583118 D 1134782 CDS YP_006770180.1 410482634 13688995 2584344..2585363 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase 2585363 13688995 O3M_12680 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770180.1 2584344 D 1134782 CDS YP_006770181.1 410482635 13688996 2585505..2586788 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 2586788 13688996 O3M_12685 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770181.1 2585505 D 1134782 CDS YP_006770182.1 410482636 13688997 2586877..2588337 1 NC_018650.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannonate dehydrogenase 2588337 13688997 O3M_12690 Escherichia coli O104:H4 str. 2009EL-2050 mannonate dehydrogenase YP_006770182.1 2586877 D 1134782 CDS YP_006770183.1 410482637 13688998 complement(2588373..2588576) 1 NC_018650.1 selenoprotein ydfZ 2588576 13688998 O3M_12695 Escherichia coli O104:H4 str. 2009EL-2050 selenoprotein ydfZ YP_006770183.1 2588373 R 1134782 CDS YP_006770184.1 410482638 13688999 complement(2588754..2589440) 1 NC_018650.1 COG1802 Transcriptional regulators; hypothetical protein 2589440 13688999 O3M_12700 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770184.1 2588754 R 1134782 CDS YP_006770185.1 410482639 13689000 complement(2589529..2590275) 1 NC_018650.1 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; malonic semialdehyde reductase 2590275 13689000 O3M_12705 Escherichia coli O104:H4 str. 2009EL-2050 malonic semialdehyde reductase YP_006770185.1 2589529 R 1134782 CDS YP_006770186.1 410482640 13689001 2590412..2592457 1 NC_018650.1 COG0339 Zn-dependent oligopeptidases; dipeptidyl carboxypeptidase II 2592457 13689001 O3M_12710 Escherichia coli O104:H4 str. 2009EL-2050 dipeptidyl carboxypeptidase II YP_006770186.1 2590412 D 1134782 CDS YP_006770187.1 410482641 13689002 complement(2592502..2593020) 1 NC_018650.1 COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein 2593020 13689002 O3M_12715 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770187.1 2592502 R 1134782 CDS YP_006770188.1 410482642 13689003 2593296..2593688 1 NC_018650.1 COG3111 Uncharacterized conserved protein; hypothetical protein 2593688 13689003 O3M_12720 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770188.1 2593296 D 1134782 CDS YP_006770189.1 410482643 13689004 2593943..2594833 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 2594833 13689004 O3M_12725 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006770189.1 2593943 D 1134782 CDS YP_006770190.1 410482644 13689005 complement(2595053..2595148) 1 NC_018650.1 hypothetical protein 2595148 13689005 O3M_12730 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770190.1 2595053 R 1134782 CDS YP_006770191.1 410482645 13689006 complement(2595275..2596462) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 2596462 13689006 O3M_12735 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770191.1 2595275 R 1134782 CDS YP_006770192.1 410482646 13689007 2596657..2597556 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; O-acetylserine/cysteine export protein 2597556 13689007 O3M_12740 Escherichia coli O104:H4 str. 2009EL-2050 O-acetylserine/cysteine export protein YP_006770192.1 2596657 D 1134782 CDS YP_006770193.1 410482647 13689008 complement(2597601..2598299) 1 NC_018650.1 COG2188 Transcriptional regulators; transcriptional regulator 2598299 13689008 O3M_12745 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006770193.1 2597601 R 1134782 CDS YP_006770194.1 410482648 13689009 2598498..2598809 1 NC_018650.1 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 2598809 13689009 O3M_12750 Escherichia coli O104:H4 str. 2009EL-2050 PTS system cellobiose-specific transporter subunit IIB YP_006770194.1 2598498 D 1134782 CDS YP_006770195.1 410482649 13689010 2598924..2600246 1 NC_018650.1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system transporter subunit IIC 2600246 13689010 O3M_12755 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter subunit IIC YP_006770195.1 2598924 D 1134782 CDS YP_006770196.1 410482650 13689011 2600274..2600585 1 NC_018650.1 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 2600585 13689011 O3M_12760 Escherichia coli O104:H4 str. 2009EL-2050 PTS system cellobiose-specific transporter subunit IIA YP_006770196.1 2600274 D 1134782 CDS YP_006770197.1 410482651 13689012 2600641..2602314 1 NC_018650.1 COG0789 Predicted transcriptional regulators; carbohydrate-specific outer membrane porin 2602314 13689012 O3M_12765 Escherichia coli O104:H4 str. 2009EL-2050 carbohydrate-specific outer membrane porin YP_006770197.1 2600641 D 1134782 CDS YP_006770198.1 410482652 13689013 2602339..2603778 1 NC_018650.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; 6-phospho-beta-glucosidase 2603778 celA 13689013 celA Escherichia coli O104:H4 str. 2009EL-2050 6-phospho-beta-glucosidase YP_006770198.1 2602339 D 1134782 CDS YP_006770199.1 410482653 13689014 complement(2603835..2604053) 1 NC_018650.1 hypothetical protein 2604053 13689014 O3M_12775 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770199.1 2603835 R 1134782 CDS YP_006770200.1 410482654 13689015 complement(2604085..2604468) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator MarA 2604468 13689015 O3M_12780 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator MarA YP_006770200.1 2604085 R 1134782 CDS YP_006770201.1 410482655 13689016 complement(2604488..2604922) 1 NC_018650.1 COG1846 Transcriptional regulators; DNA-binding transcriptional repressor MarR 2604922 13689016 O3M_12785 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor MarR YP_006770201.1 2604488 R 1134782 CDS YP_006770202.1 410482656 13689017 2605134..2605799 1 NC_018650.1 COG2095 Multiple antibiotic transporter; inner membrane protein 2605799 13689017 O3M_12790 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770202.1 2605134 D 1134782 CDS YP_006770203.1 410482657 13689018 complement(2605824..2607014) 1 NC_018650.1 COG2814 Arabinose efflux permease; arabinose transporter 2607014 13689018 O3M_12795 Escherichia coli O104:H4 str. 2009EL-2050 arabinose transporter YP_006770203.1 2605824 R 1134782 CDS YP_006770204.1 410482658 13689019 complement(2607164..2607412) 1 NC_018650.1 hypothetical protein 2607412 13689019 O3M_12800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770204.1 2607164 R 1134782 CDS YP_006770205.1 410482659 13689020 complement(2607819..2608277) 1 NC_018650.1 hypothetical protein 2608277 13689020 O3M_12805 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770205.1 2607819 R 1134782 CDS YP_006770206.1 410482660 13689021 complement(2608355..2609236) 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2609236 13689021 O3M_12810 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006770206.1 2608355 R 1134782 CDS YP_006770207.1 410482661 13689022 2609337..2610725 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; succinate-semialdehyde dehydrogenase 2610725 13689022 O3M_12815 Escherichia coli O104:H4 str. 2009EL-2050 succinate-semialdehyde dehydrogenase YP_006770207.1 2609337 D 1134782 CDS YP_006770208.1 410482662 13689023 2610789..2611715 1 NC_018650.1 COG2066 Glutaminase; glutaminase 2611715 13689023 O3M_12820 Escherichia coli O104:H4 str. 2009EL-2050 glutaminase YP_006770208.1 2610789 D 1134782 CDS YP_006770209.1 410482663 13689024 2611715..2612074 1 NC_018650.1 hypothetical protein 2612074 13689024 O3M_12825 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770209.1 2611715 D 1134782 CDS YP_006770210.1 410482664 13689025 2612213..2613631 1 NC_018650.1 COG2199 FOG: GGDEF domain; hypothetical protein 2613631 13689025 O3M_12830 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770210.1 2612213 D 1134782 CDS YP_006770211.1 410482665 13689026 2613858..2615309 1 NC_018650.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; altronate oxidoreductase 2615309 13689026 O3M_12835 Escherichia coli O104:H4 str. 2009EL-2050 altronate oxidoreductase YP_006770211.1 2613858 D 1134782 CDS YP_006770212.1 410482666 13689027 2615516..2616430 1 NC_018650.1 COG3781 Predicted membrane protein; hypothetical protein 2616430 13689027 O3M_12840 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770212.1 2615516 D 1134782 CDS YP_006770213.1 410482667 13689028 complement(2616434..2617192) 1 NC_018650.1 COG4106 Trans-aconitate methyltransferase; trans-aconitate 2-methyltransferase 2617192 13689028 O3M_12845 Escherichia coli O104:H4 str. 2009EL-2050 trans-aconitate 2-methyltransferase YP_006770213.1 2616434 R 1134782 CDS YP_006770214.1 410482668 13689029 complement(2617249..2617539) 1 NC_018650.1 COG1359 Uncharacterized conserved protein; autoinducer-2 (AI-2) modifying protein LsrG 2617539 13689029 O3M_12850 Escherichia coli O104:H4 str. 2009EL-2050 autoinducer-2 (AI-2) modifying protein LsrG YP_006770214.1 2617249 R 1134782 CDS YP_006770215.1 410482669 13689030 complement(2617563..2618438) 1 NC_018650.1 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes; autoinducer 2 aldolase 2618438 13689030 O3M_12855 Escherichia coli O104:H4 str. 2009EL-2050 autoinducer 2 aldolase YP_006770215.1 2617563 R 1134782 CDS YP_006770216.1 410482670 13689031 complement(2618465..2619487) 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; autoinducer 2-binding protein lsrB 2619487 13689031 O3M_12860 Escherichia coli O104:H4 str. 2009EL-2050 autoinducer 2-binding protein lsrB YP_006770216.1 2618465 R 1134782 CDS YP_006770217.1 410482671 13689032 complement(2619499..2620491) 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; autoinducer 2 import system permease LsrD 2620491 13689032 O3M_12865 Escherichia coli O104:H4 str. 2009EL-2050 autoinducer 2 import system permease LsrD YP_006770217.1 2619499 R 1134782 CDS YP_006770218.1 410482672 13689033 complement(2620491..2621519) 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; autoinducer 2 ABC transporter permease LsrC 2621519 13689033 O3M_12870 Escherichia coli O104:H4 str. 2009EL-2050 autoinducer 2 ABC transporter permease LsrC YP_006770218.1 2620491 R 1134782 CDS YP_006770219.1 410482673 13689034 complement(2621513..2623048) 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; autoinducer 2 ABC transporter ATP-binding protein LsrA 2623048 13689034 O3M_12875 Escherichia coli O104:H4 str. 2009EL-2050 autoinducer 2 ABC transporter ATP-binding protein LsrA YP_006770219.1 2621513 R 1134782 CDS YP_006770220.1 410482674 13689035 2623297..2624250 1 NC_018650.1 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; transcriptional regulator LsrR 2624250 13689035 O3M_12880 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator LsrR YP_006770220.1 2623297 D 1134782 CDS YP_006770221.1 410482675 13689036 2624329..2625921 1 NC_018650.1 COG1070 Sugar (pentulose and hexulose) kinases; autoinducer-2 (AI-2) kinase 2625921 13689036 O3M_12885 Escherichia coli O104:H4 str. 2009EL-2050 autoinducer-2 (AI-2) kinase YP_006770221.1 2624329 D 1134782 CDS YP_006770222.1 410482676 13689037 2626452..2630429 1 NC_018650.1 COG5295 Autotransporter adhesin; lipoprotein 2630429 13689037 O3M_12890 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770222.1 2626452 D 1134782 CDS YP_006770223.1 410482677 13689038 2630473..2631873 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; lipoprotein/autotransporter domain-containing protein 2631873 13689038 O3M_12895 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein/autotransporter domain-containing protein YP_006770223.1 2630473 D 1134782 CDS YP_006770224.1 410482678 13689039 2632082..2632348 1 NC_018650.1 COG1396 Predicted transcriptional regulators; antitoxin HipB 2632348 13689039 O3M_12900 Escherichia coli O104:H4 str. 2009EL-2050 antitoxin HipB YP_006770224.1 2632082 D 1134782 CDS YP_006770225.1 410482679 13689040 2632348..2633670 1 NC_018650.1 COG3550 Uncharacterized protein related to capsule biosynthesis enzymes; regulator with hipB 2633670 13689040 O3M_12905 Escherichia coli O104:H4 str. 2009EL-2050 regulator with hipB YP_006770225.1 2632348 D 1134782 CDS YP_006770226.1 410482680 13689041 2633988..2634167 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator 2634167 13689041 O3M_12910 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006770226.1 2633988 D 1134782 CDS YP_006770227.1 410482681 13689042 2634623..2635186 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; major fimbrial subunit FmlA 2635186 13689042 O3M_12915 Escherichia coli O104:H4 str. 2009EL-2050 major fimbrial subunit FmlA YP_006770227.1 2634623 D 1134782 CDS YP_006770228.1 410482682 13689043 2635520..2636230 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein 2636230 13689043 O3M_12920 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial chaperone protein YP_006770228.1 2635520 D 1134782 CDS YP_006770229.1 410482683 13689044 2636272..2638923 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 2638923 13689044 O3M_12925 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial outer membrane usher protein YP_006770229.1 2636272 D 1134782 CDS YP_006770230.1 410482684 13689045 2638937..2639467 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 2639467 13689045 O3M_12930 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006770230.1 2638937 D 1134782 CDS YP_006770231.1 410482685 13689046 2639480..2639983 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 2639983 13689046 O3M_12935 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006770231.1 2639480 D 1134782 CDS YP_006770232.1 410482686 13689047 2640042..2640956 1 NC_018650.1 fimbrial-like adhesin protein 2640956 13689047 O3M_12940 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006770232.1 2640042 D 1134782 CDS YP_006770233.1 410482687 13689048 2641290..2643569 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; oxidoreductase 2643569 13689048 O3M_12945 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770233.1 2641290 D 1134782 CDS YP_006770234.1 410482688 13689049 2643817..2644014 1 NC_018650.1 hypothetical protein 2644014 13689049 O3M_12950 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770234.1 2643817 D 1134782 CDS YP_006770235.1 410482689 13689050 2644089..2644850 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator YdeO 2644850 13689050 O3M_12955 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YdeO YP_006770235.1 2644089 D 1134782 CDS YP_006770236.1 410482690 13689051 2645252..2645761 1 NC_018650.1 COG3119 Arylsulfatase A and related enzymes; sulfatase 2645761 13689051 O3M_12960 Escherichia coli O104:H4 str. 2009EL-2050 sulfatase YP_006770236.1 2645252 D 1134782 CDS YP_006770237.1 410482691 13689052 2645807..2646787 1 NC_018650.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 2646787 13689052 O3M_12965 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006770237.1 2645807 D 1134782 CDS YP_006770238.1 410482692 13689053 2646949..2648133 1 NC_018650.1 COG3119 Arylsulfatase A and related enzymes; hypothetical protein 2648133 13689053 O3M_12970 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770238.1 2646949 D 1134782 CDS YP_006770239.1 410482693 13689054 2648185..2649342 1 NC_018650.1 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); hypothetical protein 2649342 13689054 O3M_12975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770239.1 2648185 D 1134782 CDS YP_006770240.1 410482694 13689055 2649633..2651318 1 NC_018650.1 permease and ATP-binding component; COG4178 ABC-type uncharacterized transport system, permease and ATPase components; multidrug ABC transporter 2651318 13689055 O3M_12980 Escherichia coli O104:H4 str. 2009EL-2050 multidrug ABC transporter YP_006770240.1 2649633 D 1134782 CDS YP_006770241.1 410482695 13689056 2651356..2653728 1 NC_018650.1 COG1629 Outer membrane receptor proteins, mostly Fe transport; porin protein 2653728 13689056 O3M_12985 Escherichia coli O104:H4 str. 2009EL-2050 porin protein YP_006770241.1 2651356 D 1134782 CDS YP_006770242.1 410482696 13689057 2653773..2656568 1 NC_018650.1 COG0612 Predicted Zn-dependent peptidases; membrane-associated peptidase 2656568 13689057 O3M_12990 Escherichia coli O104:H4 str. 2009EL-2050 membrane-associated peptidase YP_006770242.1 2653773 D 1134782 CDS YP_006770243.1 410482697 13689058 2656930..2658330 1 NC_018650.1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins; glutamate decarboxylase 2658330 13689058 O3M_12995 Escherichia coli O104:H4 str. 2009EL-2050 glutamate decarboxylase YP_006770243.1 2656930 D 1134782 CDS YP_006770244.1 410482698 13689059 2658486..2660021 1 NC_018650.1 COG0531 Amino acid transporters; glutamate/gamma-aminobutyrate antiporter 2660021 13689059 O3M_13000 Escherichia coli O104:H4 str. 2009EL-2050 glutamate/gamma-aminobutyrate antiporter YP_006770244.1 2658486 D 1134782 CDS YP_006770245.1 410482699 13689060 2660152..2661471 1 NC_018650.1 COG1649 Uncharacterized protein conserved in bacteria; lipoprotein 2661471 13689060 O3M_13005 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770245.1 2660152 D 1134782 CDS YP_006770246.1 410482700 13689061 2661843..2663225 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 2663225 13689061 O3M_13010 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006770246.1 2661843 D 1134782 CDS YP_006770247.1 410482701 13689062 2663250..2665649 1 NC_018650.1 COG2202 FOG: PAS/PAC domain; cyclic-di-GMP phosphodiesterase 2665649 13689062 O3M_13015 Escherichia coli O104:H4 str. 2009EL-2050 cyclic-di-GMP phosphodiesterase YP_006770247.1 2663250 D 1134782 CDS YP_006770248.1 410482702 13689063 2665907..2666488 1 NC_018650.1 COG2173 D-alanyl-D-alanine dipeptidase; D-alanyl-D-alanine dipeptidase 2666488 13689063 O3M_13020 Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-D-alanine dipeptidase YP_006770248.1 2665907 D 1134782 CDS YP_006770249.1 410482703 13689064 2666502..2668052 1 NC_018650.1 periplasmic-binding component of ABC superfamily protein; COG0747 ABC-type dipeptide transport system, periplasmic component; D-ala-D-a la transporter subunit 2668052 13689064 O3M_13025 Escherichia coli O104:H4 str. 2009EL-2050 D-ala-D-a la transporter subunit YP_006770249.1 2666502 D 1134782 CDS YP_006770250.1 410482704 13689065 2668054..2669076 1 NC_018650.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport system inner membrane protein 2669076 13689065 O3M_13030 Escherichia coli O104:H4 str. 2009EL-2050 binding-protein-dependent transport system inner membrane protein YP_006770250.1 2668054 D 1134782 CDS YP_006770251.1 410482705 13689066 2669073..2669969 1 NC_018650.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; D-ala-D-ala transporter subunit 2669969 13689066 O3M_13035 Escherichia coli O104:H4 str. 2009EL-2050 D-ala-D-ala transporter subunit YP_006770251.1 2669073 D 1134782 CDS YP_006770252.1 410482706 13689067 2669966..2670952 1 NC_018650.1 ATP-binding component of ABC superfamily protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; D-ala-D-ala transporter subunit 2670952 13689067 O3M_13040 Escherichia coli O104:H4 str. 2009EL-2050 D-ala-D-ala transporter subunit YP_006770252.1 2669966 D 1134782 CDS YP_006770253.1 410482707 13689068 2670945..2671871 1 NC_018650.1 ATP-binding component of ABC superfamily protein; COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; D-ala-D-ala transporter subunit 2671871 13689068 O3M_13045 Escherichia coli O104:H4 str. 2009EL-2050 D-ala-D-ala transporter subunit YP_006770253.1 2670945 D 1134782 CDS YP_006770254.1 410482708 13689069 complement(2671927..2672358) 1 NC_018650.1 COG1764 Predicted redox protein, regulator of disulfide bond formation; osmotically inducible, stress-inducible membrane protein OsmC 2672358 13689069 O3M_13050 Escherichia coli O104:H4 str. 2009EL-2050 osmotically inducible, stress-inducible membrane protein OsmC YP_006770254.1 2671927 R 1134782 CDS YP_006770255.1 410482709 13689070 2672704..2672919 1 NC_018650.1 biofilm-dependent modulation protein 2672919 13689070 O3M_13055 Escherichia coli O104:H4 str. 2009EL-2050 biofilm-dependent modulation protein YP_006770255.1 2672704 D 1134782 CDS YP_006770256.1 410482710 13689071 2673021..2673158 1 NC_018650.1 30S ribosomal subunit S22 2673158 rpsV 13689071 rpsV Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal subunit S22 YP_006770256.1 2673021 D 1134782 CDS YP_006770257.1 410482711 13689072 2673315..2675012 1 NC_018650.1 COG0281 Malic enzyme; malate dehydrogenase 2675012 13689072 O3M_13065 Escherichia coli O104:H4 str. 2009EL-2050 malate dehydrogenase YP_006770257.1 2673315 D 1134782 CDS YP_006770258.1 410482712 13689073 2675146..2676156 1 NC_018650.1 COG1064 Zn-dependent alcohol dehydrogenases; ethanol-active dehydrogenase/acetaldehyde-active reductase 2676156 13689073 O3M_13070 Escherichia coli O104:H4 str. 2009EL-2050 ethanol-active dehydrogenase/acetaldehyde-active reductase YP_006770258.1 2675146 D 1134782 CDS YP_006770259.1 410482713 13689074 2676303..2676587 1 NC_018650.1 COG3093 Plasmid maintenance system antidote protein; DNA-binding transcriptional regulator 2676587 13689074 O3M_13075 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770259.1 2676303 D 1134782 CDS YP_006770260.1 410482714 13689075 complement(2676638..2677291) 1 NC_018650.1 COG2864 Cytochrome b subunit of formate dehydrogenase; formate dehydrogenase-N subunit gamma 2677291 13689075 O3M_13080 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-N subunit gamma YP_006770260.1 2676638 R 1134782 CDS YP_006770261.1 410482715 13689076 complement(2677284..2678168) 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; formate dehydrogenase, nitrate-inducible, iron-sulfur subunit 2678168 13689076 O3M_13085 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit YP_006770261.1 2677284 R 1134782 CDS YP_006770262.1 410482716 13689077 2681460..2682341 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; aromatic amino acid exporter 2682341 13689077 O3M_13100 Escherichia coli O104:H4 str. 2009EL-2050 aromatic amino acid exporter YP_006770262.1 2681460 D 1134782 CDS YP_006770263.1 410482717 13689078 2682600..2682890 1 NC_018650.1 COG3203 Outer membrane protein (porin); lipoprotein 2682890 13689078 O3M_13105 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770263.1 2682600 D 1134782 CDS YP_006770264.1 410482718 13689079 2682914..2684245 1 NC_018650.1 COG4886 Leucine-rich repeat (LRR) protein; glycoprotein with ribonuclease inhibitor domain (yddK, modular protein) 2684245 13689079 O3M_13110 Escherichia coli O104:H4 str. 2009EL-2050 glycoprotein with ribonuclease inhibitor domain (yddK, modular protein) YP_006770264.1 2682914 D 1134782 CDS YP_006770265.1 410482719 13689080 2684569..2685957 1 NC_018650.1 COG2223 Nitrate/nitrite transporter; nitrate/nitrite transport protein NarU 2685957 13689080 O3M_13115 Escherichia coli O104:H4 str. 2009EL-2050 nitrate/nitrite transport protein NarU YP_006770265.1 2684569 D 1134782 CDS YP_006770266.1 410482720 13689081 2686039..2689779 1 NC_018650.1 COG5013 Nitrate reductase alpha subunit; nitrate reductase 2 subunit alpha 2689779 13689081 O3M_13120 Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase 2 subunit alpha YP_006770266.1 2686039 D 1134782 CDS YP_006770267.1 410482721 13689082 2689776..2691320 1 NC_018650.1 COG1140 Nitrate reductase beta subunit; nitrate reductase 2 (NRZ) subunit beta 2691320 13689082 O3M_13125 Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase 2 (NRZ) subunit beta YP_006770267.1 2689776 D 1134782 CDS YP_006770268.1 410482722 13689083 2691320..2692015 1 NC_018650.1 COG2180 Nitrate reductase delta subunit; nitrate reductase 2 subunit delta 2692015 13689083 O3M_13130 Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase 2 subunit delta YP_006770268.1 2691320 D 1134782 CDS YP_006770269.1 410482723 13689084 2692012..2692692 1 NC_018650.1 COG2181 Nitrate reductase gamma subunit; nitrate reductase 2 (NRZ) subunit gamma 2692692 13689084 O3M_13135 Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase 2 (NRZ) subunit gamma YP_006770269.1 2692012 D 1134782 CDS YP_006770270.1 410482724 13689085 2692771..2693664 1 NC_018650.1 COG0384 Predicted epimerase, PhzC/PhzF homolog; hypothetical protein 2693664 13689085 O3M_13140 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770270.1 2692771 D 1134782 CDS YP_006770271.1 410482725 13689086 complement(2693760..2694605) 1 NC_018650.1 COG2162 Arylamine N-acetyltransferase; N-hydroxyarylamine O-acetyltransferase 2694605 13689086 O3M_13145 Escherichia coli O104:H4 str. 2009EL-2050 N-hydroxyarylamine O-acetyltransferase YP_006770271.1 2693760 R 1134782 CDS YP_006770272.1 410482726 13689087 2694778..2695347 1 NC_018650.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein 2695347 13689087 O3M_13150 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770272.1 2694778 D 1134782 CDS YP_006770273.1 410482727 13689088 complement(2695351..2695578) 1 NC_018650.1 COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; 4-oxalocrotonate tautomerase 2695578 13689088 O3M_13155 Escherichia coli O104:H4 str. 2009EL-2050 4-oxalocrotonate tautomerase YP_006770273.1 2695351 R 1134782 CDS YP_006770274.1 410482728 13689089 complement(2695611..2696309) 1 NC_018650.1 COG5433 Transposase; H repeat-associated protein 2696309 13689089 O3M_13160 Escherichia coli O104:H4 str. 2009EL-2050 H repeat-associated protein YP_006770274.1 2695611 R 1134782 CDS YP_006770275.1 410482729 13689090 complement(2696663..2697109) 1 NC_018650.1 hypothetical protein 2697109 13689090 O3M_13165 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770275.1 2696663 R 1134782 CDS YP_006770276.1 410482730 13689091 complement(2697124..2701365) 1 NC_018650.1 COG3209 Rhs family protein; rhsD element protein 2701365 13689091 O3M_13170 Escherichia coli O104:H4 str. 2009EL-2050 rhsD element protein YP_006770276.1 2697124 R 1134782 CDS YP_006770277.1 410482731 13689092 complement(2701433..2703541) 1 NC_018650.1 Encoded within repeats that are hotspots for chromosomal duplication formation: Function unknown; COG3501 Uncharacterized protein conserved in bacteria; VgrG protein 2703541 13689092 O3M_13175 Escherichia coli O104:H4 str. 2009EL-2050 VgrG protein YP_006770277.1 2701433 R 1134782 CDS YP_006770278.1 410482732 13689093 complement(2704361..2704573) 1 NC_018650.1 hypothetical protein 2704573 13689093 O3M_13180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770278.1 2704361 R 1134782 CDS YP_006770279.1 410482733 13689094 complement(2704649..2705266) 1 NC_018650.1 COG0625 Glutathione S-transferase; glutathione S-transferase-like protein 2705266 13689094 O3M_13185 Escherichia coli O104:H4 str. 2009EL-2050 glutathione S-transferase-like protein YP_006770279.1 2704649 R 1134782 CDS YP_006770280.1 410482734 13689095 2705533..2707032 1 NC_018650.1 COG1113 Gamma-aminobutyrate permease and related permeases; L-asparagine permease 2707032 13689095 O3M_13190 Escherichia coli O104:H4 str. 2009EL-2050 L-asparagine permease YP_006770280.1 2705533 D 1134782 CDS YP_006770281.1 410482735 13689096 complement(2707145..2708206) 1 NC_018650.1 COG3391 Uncharacterized conserved protein; hypothetical protein 2708206 13689096 O3M_13195 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770281.1 2707145 R 1134782 CDS YP_006770282.1 410482736 13689097 2708448..2710550 1 NC_018650.1 COG1629 Outer membrane receptor proteins, mostly Fe transport; iron outer membrane receptor 2710550 13689097 O3M_13200 Escherichia coli O104:H4 str. 2009EL-2050 iron outer membrane receptor YP_006770282.1 2708448 D 1134782 CDS YP_006770283.1 410482737 13689098 complement(2710586..2711251) 1 NC_018650.1 COG1802 Transcriptional regulators; colanic acid/biofilm transcriptional regulator 2711251 13689098 O3M_13205 Escherichia coli O104:H4 str. 2009EL-2050 colanic acid/biofilm transcriptional regulator YP_006770283.1 2710586 R 1134782 CDS YP_006770284.1 410482738 13689099 complement(2711449..2712486) 1 NC_018650.1 COG2130 Putative NADP-dependent oxidoreductases; oxidoreductase 2712486 13689099 O3M_13210 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770284.1 2711449 R 1134782 CDS YP_006770285.1 410482739 13689100 2712667..2713185 1 NC_018650.1 COG1247 Sortase and related acyltransferases; acyl-CoA N-acyltransferase 2713185 13689100 O3M_13215 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA N-acyltransferase YP_006770285.1 2712667 D 1134782 CDS YP_006770286.1 410482740 13689101 2713182..2713631 1 NC_018650.1 COG3238 Uncharacterized protein conserved in bacteria; inner membrane protein 2713631 13689101 O3M_13220 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770286.1 2713182 D 1134782 CDS YP_006770287.1 410482741 13689102 complement(2713632..2713865) 1 NC_018650.1 hypothetical protein 2713865 13689102 O3M_13225 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770287.1 2713632 R 1134782 CDS YP_006770288.1 410482742 13689103 complement(2713951..2714124) 1 NC_018650.1 hypothetical protein 2714124 13689103 O3M_13230 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770288.1 2713951 R 1134782 CDS YP_006770289.1 410482743 13689104 complement(2714816..2715625) 1 NC_018650.1 COG0110 Acetyltransferase (isoleucine patch superfamily); acetyltransferase 2715625 13689104 O3M_13235 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006770289.1 2714816 R 1134782 CDS YP_006770290.1 410482744 13689105 complement(2715835..2717259) 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; gamma-aminobutyraldehyde dehydrogenase 2717259 13689105 O3M_13240 Escherichia coli O104:H4 str. 2009EL-2050 gamma-aminobutyraldehyde dehydrogenase YP_006770290.1 2715835 R 1134782 CDS YP_006770291.1 410482745 13689106 complement(2717281..2718075) 1 NC_018650.1 COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease 2718075 13689106 O3M_13245 Escherichia coli O104:H4 str. 2009EL-2050 spermidine/putrescine ABC transporter permease YP_006770291.1 2717281 R 1134782 CDS YP_006770292.1 410482746 13689107 complement(2718065..2719006) 1 NC_018650.1 COG1176 ABC-type spermidine/putrescine transport system, permease component I; ABC transporter permease 2719006 13689107 O3M_13250 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter permease YP_006770292.1 2718065 R 1134782 CDS YP_006770293.1 410482747 13689108 complement(2719007..2720020) 1 NC_018650.1 ATP-binding component of ABC superfamily transporter; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine transporter subunit 2720020 13689108 O3M_13255 Escherichia coli O104:H4 str. 2009EL-2050 spermidine/putrescine transporter subunit YP_006770293.1 2719007 R 1134782 CDS YP_006770294.1 410482748 13689109 complement(2720038..2721183) 1 NC_018650.1 COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine transporter subunit 2721183 13689109 O3M_13260 Escherichia coli O104:H4 str. 2009EL-2050 spermidine/putrescine transporter subunit YP_006770294.1 2720038 R 1134782 CDS YP_006770295.1 410482749 13689110 complement(2721428..2722834) 1 NC_018650.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; DNA-binding transcriptional regulator 2722834 13689110 O3M_13265 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770295.1 2721428 R 1134782 CDS YP_006770296.1 410482750 13689111 complement(2722913..2723350) 1 NC_018650.1 COG1598 Uncharacterized conserved protein; DNA-binding transcriptional regulator 2723350 13689111 O3M_13270 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770296.1 2722913 R 1134782 CDS YP_006770297.1 410482751 13689112 2723751..2723981 1 NC_018650.1 hypothetical protein 2723981 13689112 O3M_13275 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770297.1 2723751 D 1134782 CDS YP_006770298.1 410482752 13689113 complement(2724073..2726034) 1 NC_018650.1 COG0826 Collagenase and related proteases; peptidase, U32 family protein 2726034 13689113 O3M_13280 Escherichia coli O104:H4 str. 2009EL-2050 peptidase, U32 family protein YP_006770298.1 2724073 R 1134782 CDS YP_006770299.1 410482753 13689114 complement(2726107..2726643) 1 NC_018650.1 COG1396 Predicted transcriptional regulators; DNA-binding transcriptional regulator 2726643 13689114 O3M_13285 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770299.1 2726107 R 1134782 CDS YP_006770300.1 410482754 13689115 2726735..2727910 1 NC_018650.1 COG3135 Uncharacterized protein involved in benzoate metabolism; benzoate transporter 2727910 13689115 O3M_13290 Escherichia coli O104:H4 str. 2009EL-2050 benzoate transporter YP_006770300.1 2726735 D 1134782 CDS YP_006770301.1 410482755 13689116 complement(2727950..2729158) 1 NC_018650.1 COG0675 Transposase and inactivated derivatives; transposase 2729158 13689116 O3M_13295 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006770301.1 2727950 R 1134782 CDS YP_006770302.1 410482756 13689117 complement(2729685..2730353) 1 NC_018650.1 hypothetical protein 2730353 13689117 O3M_13310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770302.1 2729685 R 1134782 CDS YP_006770303.1 410482757 13689118 complement(2730656..2731249) 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; tellurite resistance protein TehB 2731249 13689118 O3M_13315 Escherichia coli O104:H4 str. 2009EL-2050 tellurite resistance protein TehB YP_006770303.1 2730656 R 1134782 CDS YP_006770304.1 410482758 13689119 complement(2731246..2732238) 1 NC_018650.1 COG1275 Tellurite resistance protein and related permeases; potassium-tellurite ethidium and proflavin transporter 2732238 13689119 O3M_13320 Escherichia coli O104:H4 str. 2009EL-2050 potassium-tellurite ethidium and proflavin transporter YP_006770304.1 2731246 R 1134782 CDS YP_006770305.1 410482759 13689120 2732362..2733342 1 NC_018650.1 COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; hypothetical protein 2733342 13689120 O3M_13325 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770305.1 2732362 D 1134782 CDS YP_006770306.1 410482760 13689121 complement(2733337..2733873) 1 NC_018650.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-L7/L12-serine acetyltransferase 2733873 13689121 O3M_13330 Escherichia coli O104:H4 str. 2009EL-2050 ribosomal-protein-L7/L12-serine acetyltransferase YP_006770306.1 2733337 R 1134782 CDS YP_006770307.1 410482761 13689122 complement(2733936..2734160) 1 NC_018650.1 COG2841 Uncharacterized protein conserved in bacteria; hypothetical protein 2734160 13689122 O3M_13335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770307.1 2733936 R 1134782 CDS YP_006770308.1 410482762 13689123 2734176..2734379 1 NC_018650.1 hypothetical protein 2734379 13689123 O3M_13340 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770308.1 2734176 D 1134782 CDS YP_006770309.1 410482763 13689124 complement(2734300..2735955) 1 NC_018650.1 COG3131 Periplasmic glucans biosynthesis protein; glucan biosynthesis protein D 2735955 mdoD 13689124 mdoD Escherichia coli O104:H4 str. 2009EL-2050 glucan biosynthesis protein D YP_006770309.1 2734300 R 1134782 CDS YP_006770310.1 410482764 13689125 complement(2736180..2737523) 1 NC_018650.1 COG5383 Uncharacterized protein conserved in bacteria; hypothetical protein 2737523 13689125 O3M_13350 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770310.1 2736180 R 1134782 CDS YP_006770311.1 410482765 13689126 2737740..2738663 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional regulator 2738663 13689126 O3M_13355 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006770311.1 2737740 D 1134782 CDS YP_006770312.1 410482766 13689127 complement(2738701..2740341) 1 NC_018650.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 2740341 13689127 O3M_13360 Escherichia coli O104:H4 str. 2009EL-2050 methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor YP_006770312.1 2738701 R 1134782 CDS YP_006770313.1 410482767 13689128 2740740..2740889 1 NC_018650.1 small toxic polypeptide 2740889 13689128 O3M_13365 Escherichia coli O104:H4 str. 2009EL-2050 small toxic polypeptide YP_006770313.1 2740740 D 1134782 CDS YP_006770314.1 410482768 13689129 complement(2740961..2741134) 1 NC_018650.1 hypothetical protein 2741134 13689129 O3M_13370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770314.1 2740961 R 1134782 CDS YP_006770315.1 410482769 13689130 complement(2741379..2741909) 1 NC_018650.1 COG3038 Cytochrome B561; cytochrome b561 2741909 13689130 O3M_13375 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome b561 YP_006770315.1 2741379 R 1134782 CDS YP_006770316.1 410482770 13689131 2742098..2743099 1 NC_018650.1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2743099 13689131 O3M_13380 Escherichia coli O104:H4 str. 2009EL-2050 glyceraldehyde-3-phosphate dehydrogenase YP_006770316.1 2742098 D 1134782 CDS YP_006770317.1 410482771 13689132 complement(2743141..2744580) 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase A 2744580 13689132 O3M_13385 Escherichia coli O104:H4 str. 2009EL-2050 aldehyde dehydrogenase A YP_006770317.1 2743141 R 1134782 CDS YP_006770318.1 410482772 13689133 complement(2744777..2745577) 1 NC_018650.1 COG1434 Uncharacterized conserved protein; hypothetical protein 2745577 13689133 O3M_13390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770318.1 2744777 R 1134782 CDS YP_006770319.1 410482773 13689134 complement(2745759..2746262) 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 2746262 13689134 O3M_13395 Escherichia coli O104:H4 str. 2009EL-2050 transposase InsB IS1 YP_006770319.1 2745759 R 1134782 CDS YP_006770320.1 410482774 13689135 complement(2746181..2746456) 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 2746456 13689135 O3M_13400 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006770320.1 2746181 R 1134782 CDS YP_006770321.1 410482775 13689136 complement(2746625..2750470) 1 NC_018650.1 COG1643 HrpA-like helicases; ATP-dependent RNA helicase HrpA 2750470 13689136 O3M_13405 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent RNA helicase HrpA YP_006770321.1 2746625 R 1134782 CDS YP_006770322.1 410482776 13689137 2750728..2751333 1 NC_018650.1 COG1182 Acyl carrier protein phosphodiesterase; azoreductase 2751333 13689137 O3M_13410 Escherichia coli O104:H4 str. 2009EL-2050 azoreductase YP_006770322.1 2750728 D 1134782 CDS YP_006770323.1 410482777 13689138 complement(2751384..2752676) 1 NC_018650.1 COG0671 Membrane-associated phospholipid phosphatase; membrane associated phosphatase 2752676 13689138 O3M_13415 Escherichia coli O104:H4 str. 2009EL-2050 membrane associated phosphatase YP_006770323.1 2751384 R 1134782 CDS YP_006770324.1 410482778 13689139 complement(2752690..2754447) 1 NC_018650.1 COG2267 Lysophospholipase; hydrolase 2754447 13689139 O3M_13420 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006770324.1 2752690 R 1134782 CDS YP_006770325.1 410482779 13689140 complement(2754463..2755359) 1 NC_018650.1 COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; membrane associated CTP-phosphosubstrate transferase 2755359 13689140 O3M_13425 Escherichia coli O104:H4 str. 2009EL-2050 membrane associated CTP-phosphosubstrate transferase YP_006770325.1 2754463 R 1134782 CDS YP_006770326.1 410482780 13689141 complement(2755359..2755964) 1 NC_018650.1 COG0558 Phosphatidylglycerophosphate synthase; inner membrane protein 2755964 13689141 O3M_13430 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770326.1 2755359 R 1134782 CDS YP_006770327.1 410482781 13689142 complement(2756135..2758441) 1 NC_018650.1 hypothetical protein 2758441 13689142 O3M_13435 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770327.1 2756135 R 1134782 CDS YP_006770328.1 410482782 13689143 complement(2758505..2759365) 1 NC_018650.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 2759365 13689143 O3M_13440 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770328.1 2758505 R 1134782 CDS YP_006770329.1 410482783 13689144 complement(2759595..2760185) 1 NC_018650.1 COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; hexapeptide repeat acetyltransferase 2760185 13689144 O3M_13445 Escherichia coli O104:H4 str. 2009EL-2050 hexapeptide repeat acetyltransferase YP_006770329.1 2759595 R 1134782 CDS YP_006770330.1 410482784 13689145 complement(2760167..2761117) 1 NC_018650.1 COG3327 Phenylacetic acid-responsive transcriptional repressor; DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive 2761117 13689145 O3M_13450 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive YP_006770330.1 2760167 R 1134782 CDS YP_006770331.1 410482785 13689146 complement(2761218..2762531) 1 NC_018650.1 COG1541 Coenzyme F390 synthetase; phenylacetate-CoA ligase 2762531 13689146 O3M_13455 Escherichia coli O104:H4 str. 2009EL-2050 phenylacetate-CoA ligase YP_006770331.1 2761218 R 1134782 CDS YP_006770332.1 410482786 13689147 complement(2762558..2763763) 1 NC_018650.1 COG0183 Acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase 2763763 13689147 O3M_13460 Escherichia coli O104:H4 str. 2009EL-2050 beta-ketoadipyl CoA thiolase YP_006770332.1 2762558 R 1134782 CDS YP_006770333.1 410482787 13689148 complement(2763763..2764185) 1 NC_018650.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; thioesterase 2764185 13689148 O3M_13465 Escherichia coli O104:H4 str. 2009EL-2050 thioesterase YP_006770333.1 2763763 R 1134782 CDS YP_006770334.1 410482788 13689149 complement(2764175..2765602) 1 NC_018650.1 COG1250 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase 2765602 13689149 O3M_13470 Escherichia coli O104:H4 str. 2009EL-2050 3-hydroxyacyl-CoA dehydrogenase YP_006770334.1 2764175 R 1134782 CDS YP_006770335.1 410482789 13689150 complement(2765604..2766392) 1 NC_018650.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase 2766392 13689150 O3M_13475 Escherichia coli O104:H4 str. 2009EL-2050 enoyl-CoA hydratase YP_006770335.1 2765604 R 1134782 CDS YP_006770336.1 410482790 13689151 complement(2766392..2767159) 1 NC_018650.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase-isomerase 2767159 13689151 O3M_13480 Escherichia coli O104:H4 str. 2009EL-2050 enoyl-CoA hydratase-isomerase YP_006770336.1 2766392 R 1134782 CDS YP_006770337.1 410482791 13689152 complement(2767156..2768226) 1 NC_018650.1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; subunit of the phenylacetly-CoA oxygenase/reductase 2768226 13689152 O3M_13485 Escherichia coli O104:H4 str. 2009EL-2050 subunit of the phenylacetly-CoA oxygenase/reductase YP_006770337.1 2767156 R 1134782 CDS YP_006770338.1 410482792 13689153 complement(2768234..2768731) 1 NC_018650.1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; multicomponent oxygenase/reductase subunit 2768731 13689153 O3M_13490 Escherichia coli O104:H4 str. 2009EL-2050 multicomponent oxygenase/reductase subunit YP_006770338.1 2768234 R 1134782 CDS YP_006770339.1 410482793 13689154 complement(2768746..2769492) 1 NC_018650.1 COG3396 Uncharacterized conserved protein; multicomponent oxygenase/reductase subunit 2769492 13689154 O3M_13495 Escherichia coli O104:H4 str. 2009EL-2050 multicomponent oxygenase/reductase subunit YP_006770339.1 2768746 R 1134782 CDS YP_006770340.1 410482794 13689155 complement(2769501..2769788) 1 NC_018650.1 COG3460 Uncharacterized enzyme of phenylacetate metabolism; phenylacetate-CoA oxygenase subunit PaaB 2769788 paaB 13689155 paaB Escherichia coli O104:H4 str. 2009EL-2050 phenylacetate-CoA oxygenase subunit PaaB YP_006770340.1 2769501 R 1134782 CDS YP_006770341.1 410482795 13689156 complement(2769800..2770729) 1 NC_018650.1 COG3396 Uncharacterized conserved protein; phenylacetate-CoA oxygenase subunit PaaA 2770729 paaA 13689156 paaA Escherichia coli O104:H4 str. 2009EL-2050 phenylacetate-CoA oxygenase subunit PaaA YP_006770341.1 2769800 R 1134782 CDS YP_006770342.1 410482796 13689157 2771014..2773059 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 2773059 13689157 O3M_13510 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase YP_006770342.1 2771014 D 1134782 CDS YP_006770343.1 410482797 13689158 2773307..2775580 1 NC_018650.1 COG3733 Cu2+-containing amine oxidase; tyramine oxidase 2775580 tynA 13689158 tynA Escherichia coli O104:H4 str. 2009EL-2050 tyramine oxidase YP_006770343.1 2773307 D 1134782 CDS YP_006770344.1 410482798 13689159 complement(2775638..2777137) 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; phenylacetaldehyde dehydrogenase 2777137 13689159 O3M_13520 Escherichia coli O104:H4 str. 2009EL-2050 phenylacetaldehyde dehydrogenase YP_006770344.1 2775638 R 1134782 CDS YP_006770345.1 410482799 13689160 2777373..2778278 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator FeaR 2778278 13689160 O3M_13525 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator FeaR YP_006770345.1 2777373 D 1134782 CDS YP_006770346.1 410482800 13689161 complement(2778450..2778776) 1 NC_018650.1 COG3784 Uncharacterized protein conserved in bacteria; hypothetical protein 2778776 13689161 O3M_13530 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770346.1 2778450 R 1134782 CDS YP_006770347.1 410482801 13689162 complement(2778784..2778969) 1 NC_018650.1 lipoprotein 2778969 13689162 O3M_13535 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770347.1 2778784 R 1134782 CDS YP_006770348.1 410482802 13689163 complement(2778966..2781605) 1 NC_018650.1 hypothetical protein 2781605 13689163 O3M_13540 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770348.1 2778966 R 1134782 CDS YP_006770349.1 410482803 13689164 2781813..2782802 1 NC_018650.1 COG1052 Lactate dehydrogenase and related dehydrogenases; D-lactate dehydrogenase 2782802 13689164 O3M_13545 Escherichia coli O104:H4 str. 2009EL-2050 D-lactate dehydrogenase YP_006770349.1 2781813 D 1134782 CDS YP_006770350.1 410482804 13689165 2782913..2783335 1 NC_018650.1 COG3187 Heat shock protein; heat-inducible protein 2783335 13689165 O3M_13550 Escherichia coli O104:H4 str. 2009EL-2050 heat-inducible protein YP_006770350.1 2782913 D 1134782 CDS YP_006770351.1 410482805 13689166 complement(2783332..2783598) 1 NC_018650.1 COG3042 Putative hemolysin; hypothetical protein 2783598 13689166 O3M_13555 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770351.1 2783332 R 1134782 CDS YP_006770352.1 410482806 13689167 2783872..2787396 1 NC_018650.1 4Fe-4S cluster binding protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; fused 2-oxoacid-flavodoxin oxidoreductase/hypothetical protein 2787396 13689167 O3M_13560 Escherichia coli O104:H4 str. 2009EL-2050 fused 2-oxoacid-flavodoxin oxidoreductase/hypothetical protein YP_006770352.1 2783872 D 1134782 CDS YP_006770353.1 410482807 13689168 2787763..2788896 1 NC_018650.1 COG3203 Outer membrane protein (porin); outer membrane pore protein N, non-specific 2788896 13689168 O3M_13565 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane pore protein N, non-specific YP_006770353.1 2787763 D 1134782 CDS YP_006770354.1 410482808 13689169 2789037..2789471 1 NC_018650.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein F 2789471 13689169 O3M_13570 Escherichia coli O104:H4 str. 2009EL-2050 universal stress protein F YP_006770354.1 2789037 D 1134782 CDS YP_006770355.1 410482809 13689170 2789647..2790582 1 NC_018650.1 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA 2-thiocytidine biosynthesis protein TtcA 2790582 13689170 O3M_13575 Escherichia coli O104:H4 str. 2009EL-2050 tRNA 2-thiocytidine biosynthesis protein TtcA YP_006770355.1 2789647 D 1134782 CDS YP_006770356.1 410482810 13689171 complement(2790711..2792084) 1 NC_018650.1 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase DbpA 2792084 13689171 O3M_13580 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent RNA helicase DbpA YP_006770356.1 2790711 R 1134782 CDS YP_006770357.1 410482811 13689172 complement(2792114..2792287) 1 NC_018650.1 hypothetical protein 2792287 13689172 O3M_13585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770357.1 2792114 R 1134782 CDS YP_006770358.1 410482812 13689173 complement(2792562..2793545) 1 NC_018650.1 COG0598 Mg2+ and Co2+ transporters; zinc transporter 2793545 zntB 13689173 zntB Escherichia coli O104:H4 str. 2009EL-2050 zinc transporter YP_006770358.1 2792562 R 1134782 CDS YP_006770359.1 410482813 13689174 2793800..2795032 1 NC_018650.1 COG2199 FOG: GGDEF domain; hypothetical protein 2795032 13689174 O3M_13595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770359.1 2793800 D 1134782 CDS YP_006770360.1 410482814 13689175 complement(2795053..2795616) 1 NC_018650.1 COG2840 Uncharacterized protein conserved in bacteria; Smr domain-containing protein 2795616 13689175 O3M_13600 Escherichia coli O104:H4 str. 2009EL-2050 Smr domain-containing protein YP_006770360.1 2795053 R 1134782 CDS YP_006770361.1 410482815 13689176 complement(2795946..2796854) 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 2796854 13689176 O3M_13605 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770361.1 2795946 R 1134782 CDS YP_006770362.1 410482816 13689177 2797030..2798340 1 NC_018650.1 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; peptidase, aminobenzoyl-glutamate utilization protein AbgA 2798340 13689177 O3M_13610 Escherichia coli O104:H4 str. 2009EL-2050 peptidase, aminobenzoyl-glutamate utilization protein AbgA YP_006770362.1 2797030 D 1134782 CDS YP_006770363.1 410482817 13689178 2798340..2799785 1 NC_018650.1 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; peptidase, aminobenzoyl-glutamate utilization protein AbgB 2799785 13689178 O3M_13615 Escherichia coli O104:H4 str. 2009EL-2050 peptidase, aminobenzoyl-glutamate utilization protein AbgB YP_006770363.1 2798340 D 1134782 CDS YP_006770364.1 410482818 13689179 2799822..2801348 1 NC_018650.1 COG2978 Putative p-aminobenzoyl-glutamate transporter; aminobenzoyl-glutamate transporter 2801348 abgT 13689179 abgT Escherichia coli O104:H4 str. 2009EL-2050 aminobenzoyl-glutamate transporter YP_006770364.1 2799822 D 1134782 CDS YP_006770365.1 410482819 13689180 2801359..2801874 1 NC_018650.1 COG0350 Methylated DNA-protein cysteine methyltransferase; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 2801874 13689180 O3M_13625 Escherichia coli O104:H4 str. 2009EL-2050 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_006770365.1 2801359 D 1134782 CDS YP_006770366.1 410482820 13689181 2802069..2802821 1 NC_018650.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; fumarate/nitrate reduction transcriptional regulator 2802821 13689181 O3M_13630 Escherichia coli O104:H4 str. 2009EL-2050 fumarate/nitrate reduction transcriptional regulator YP_006770366.1 2802069 D 1134782 CDS YP_006770367.1 410482821 13689182 2802973..2803923 1 NC_018650.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspE 2803923 13689182 O3M_13635 Escherichia coli O104:H4 str. 2009EL-2050 universal stress protein UspE YP_006770367.1 2802973 D 1134782 CDS YP_006770368.1 410482822 13689183 complement(2803973..2804230) 1 NC_018650.1 hypothetical protein 2804230 13689183 O3M_13640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770368.1 2803973 R 1134782 CDS YP_006770369.1 410482823 13689184 2804474..2805505 1 NC_018650.1 COG0668 Small-conductance mechanosensitive channel; MscS family inner membrane protein YnaI 2805505 13689184 O3M_13645 Escherichia coli O104:H4 str. 2009EL-2050 MscS family inner membrane protein YnaI YP_006770369.1 2804474 D 1134782 CDS YP_006770370.1 410482824 13689185 complement(2805556..2807169) 1 NC_018650.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; transport periplasmic protein 2807169 13689185 O3M_13650 Escherichia coli O104:H4 str. 2009EL-2050 transport periplasmic protein YP_006770370.1 2805556 R 1134782 CDS YP_006770371.1 410482825 13689186 complement(2807292..2807417) 1 NC_018650.1 hypothetical protein 2807417 13689186 O3M_13655 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770371.1 2807292 R 1134782 CDS YP_006770372.1 410482826 13689187 complement(2807506..2808405) 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2808405 13689187 O3M_13660 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006770372.1 2807506 R 1134782 CDS YP_006770373.1 410482827 13689188 2808531..2809463 1 NC_018650.1 COG1073 Hydrolases of the alpha/beta superfamily; hydrolase 2809463 13689188 O3M_13665 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006770373.1 2808531 D 1134782 CDS YP_006770374.1 410482828 13689189 2809534..2809698 1 NC_018650.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 2809698 13689189 O3M_13670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770374.1 2809534 D 1134782 CDS YP_006770375.1 410482829 13689190 2809799..2810527 1 NC_018650.1 COG2866 Predicted carboxypeptidase; murein peptide amidase A 2810527 13689190 O3M_13675 Escherichia coli O104:H4 str. 2009EL-2050 murein peptide amidase A YP_006770375.1 2809799 D 1134782 CDS YP_006770376.1 410482830 13689191 complement(2810502..2811467) 1 NC_018650.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; L-Ala-D/L-Glu epimerase 2811467 13689191 O3M_13680 Escherichia coli O104:H4 str. 2009EL-2050 L-Ala-D/L-Glu epimerase YP_006770376.1 2810502 R 1134782 CDS YP_006770377.1 410482831 13689192 2811586..2812092 1 NC_018650.1 COG2077 Peroxiredoxin; lipid hydroperoxide peroxidase 2812092 tpx 13689192 tpx Escherichia coli O104:H4 str. 2009EL-2050 lipid hydroperoxide peroxidase YP_006770377.1 2811586 D 1134782 CDS YP_006770378.1 410482832 13689193 complement(2812136..2813677) 1 NC_018650.1 COG3283 Transcriptional regulator of aromatic amino acids metabolism; DNA-binding transcriptional regulator TyrR 2813677 13689193 O3M_13690 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator TyrR YP_006770378.1 2812136 R 1134782 CDS YP_006770379.1 410482833 13689194 complement(2813825..2814886) 1 NC_018650.1 COG3768 Predicted membrane protein; hypothetical protein 2814886 13689194 O3M_13695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770379.1 2813825 R 1134782 CDS YP_006770380.1 410482834 13689195 complement(2814883..2816280) 1 NC_018650.1 COG3106 Predicted ATPase; hypothetical protein 2816280 13689195 O3M_13700 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770380.1 2814883 R 1134782 CDS YP_006770381.1 410482835 13689196 2816435..2817433 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional regulator 2817433 13689196 O3M_13705 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770381.1 2816435 D 1134782 CDS YP_006770382.1 410482836 13689197 complement(2817544..2818449) 1 NC_018650.1 outer membrane porin 2818449 13689197 O3M_13710 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane porin YP_006770382.1 2817544 R 1134782 CDS YP_006770383.1 410482837 13689198 complement(2818494..2819576) 1 NC_018650.1 COG3839 ABC-type sugar transport systems, ATPase components; sugar transporter subunit 2819576 13689198 O3M_13715 Escherichia coli O104:H4 str. 2009EL-2050 sugar transporter subunit YP_006770383.1 2818494 R 1134782 CDS YP_006770384.1 410482838 13689199 complement(2819590..2820249) 1 NC_018650.1 COG0637 Predicted phosphatase/phosphohexomutase; beta-phosphoglucomutase 2820249 13689199 O3M_13720 Escherichia coli O104:H4 str. 2009EL-2050 beta-phosphoglucomutase YP_006770384.1 2819590 R 1134782 CDS YP_006770385.1 410482839 13689200 complement(2820246..2822513) 1 NC_018650.1 COG1554 Trehalose and maltose hydrolases (possible phosphorylases); hydrolase 2822513 13689200 O3M_13725 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006770385.1 2820246 R 1134782 CDS YP_006770386.1 410482840 13689201 complement(2822510..2823565) 1 NC_018650.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 2823565 13689201 O3M_13730 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770386.1 2822510 R 1134782 CDS YP_006770387.1 410482841 13689202 complement(2823575..2824363) 1 NC_018650.1 COG1082 Sugar phosphate isomerases/epimerases; hypothetical protein 2824363 13689202 O3M_13735 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770387.1 2823575 R 1134782 CDS YP_006770388.1 410482842 13689203 complement(2824381..2825433) 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein 2825433 13689203 O3M_13740 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase, Zn-dependent and NAD(P)-binding protein YP_006770388.1 2824381 R 1134782 CDS YP_006770389.1 410482843 13689204 complement(2825464..2826306) 1 NC_018650.1 COG0395 ABC-type sugar transport system, permease component; sugar transporter subunit 2826306 13689204 O3M_13745 Escherichia coli O104:H4 str. 2009EL-2050 sugar transporter subunit YP_006770389.1 2825464 R 1134782 CDS YP_006770390.1 410482844 13689205 complement(2826293..2827174) 1 NC_018650.1 COG1175 ABC-type sugar transport systems, permease components; sugar transporter subunit 2827174 13689205 O3M_13750 Escherichia coli O104:H4 str. 2009EL-2050 sugar transporter subunit YP_006770390.1 2826293 R 1134782 CDS YP_006770391.1 410482845 13689206 complement(2827195..2828487) 1 NC_018650.1 COG1653 ABC-type sugar transport system, periplasmic component; sugar transporter subunit 2828487 13689206 O3M_13755 Escherichia coli O104:H4 str. 2009EL-2050 sugar transporter subunit YP_006770391.1 2827195 R 1134782 CDS YP_006770392.1 410482846 13689207 complement(2828501..2830180) 1 NC_018650.1 COG0366 Glycosidases; glucosyltransferase 2830180 13689207 O3M_13760 Escherichia coli O104:H4 str. 2009EL-2050 glucosyltransferase YP_006770392.1 2828501 R 1134782 CDS YP_006770393.1 410482847 13689208 complement(2830393..2830707) 1 NC_018650.1 COG0607 Rhodanese-related sulfurtransferase; thiosulfate:cyanide sulfurtransferase 2830707 13689208 O3M_13765 Escherichia coli O104:H4 str. 2009EL-2050 thiosulfate:cyanide sulfurtransferase YP_006770393.1 2830393 R 1134782 CDS YP_006770394.1 410482848 13689209 complement(2830782..2831003) 1 NC_018650.1 peripheral inner membrane phage-shock protein 2831003 13689209 O3M_13770 Escherichia coli O104:H4 str. 2009EL-2050 peripheral inner membrane phage-shock protein YP_006770394.1 2830782 R 1134782 CDS YP_006770395.1 410482849 13689210 complement(2831012..2831371) 1 NC_018650.1 COG1983 Putative stress-responsive transcriptional regulator; DNA-binding transcriptional activator PspC 2831371 13689210 O3M_13775 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator PspC YP_006770395.1 2831012 R 1134782 CDS YP_006770396.1 410482850 13689211 complement(2831371..2831595) 1 NC_018650.1 phage shock protein B 2831595 pspB 13689211 pspB Escherichia coli O104:H4 str. 2009EL-2050 phage shock protein B YP_006770396.1 2831371 R 1134782 CDS YP_006770397.1 410482851 13689212 complement(2831649..2832317) 1 NC_018650.1 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription; phage shock protein PspA 2832317 13689212 O3M_13785 Escherichia coli O104:H4 str. 2009EL-2050 phage shock protein PspA YP_006770397.1 2831649 R 1134782 CDS YP_006770398.1 410482852 13689213 2832484..2833461 1 NC_018650.1 COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain; phage shock protein operon transcriptional activator 2833461 pspF 13689213 pspF Escherichia coli O104:H4 str. 2009EL-2050 phage shock protein operon transcriptional activator YP_006770398.1 2832484 D 1134782 CDS YP_006770399.1 410482853 13689214 complement(2833581..2834846) 1 NC_018650.1 COG0160 4-aminobutyrate aminotransferase and related aminotransferases; 4-aminobutyrate transaminase 2834846 13689214 O3M_13795 Escherichia coli O104:H4 str. 2009EL-2050 4-aminobutyrate transaminase YP_006770399.1 2833581 R 1134782 CDS YP_006770400.1 410482854 13689215 complement(2834884..2836164) 1 NC_018650.1 COG0665 Glycine/D-amino acid oxidases (deaminating); gamma-Glu-putrescine oxidase 2836164 13689215 O3M_13800 Escherichia coli O104:H4 str. 2009EL-2050 gamma-Glu-putrescine oxidase YP_006770400.1 2834884 R 1134782 CDS YP_006770401.1 410482855 13689216 complement(2836166..2837653) 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 2837653 13689216 O3M_13805 Escherichia coli O104:H4 str. 2009EL-2050 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_006770401.1 2836166 R 1134782 CDS YP_006770402.1 410482856 13689217 complement(2837928..2838485) 1 NC_018650.1 COG1396 Predicted transcriptional regulators; DNA-binding transcriptional repressor PuuR 2838485 13689217 O3M_13810 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor PuuR YP_006770402.1 2837928 R 1134782 CDS YP_006770403.1 410482857 13689218 complement(2838512..2839276) 1 NC_018650.1 COG2071 Predicted glutamine amidotransferases; gamma-glutamyl-gamma-aminobutyrate hydrolase 2839276 puuD 13689218 puuD Escherichia coli O104:H4 str. 2009EL-2050 gamma-glutamyl-gamma-aminobutyrate hydrolase YP_006770403.1 2838512 R 1134782 CDS YP_006770404.1 410482858 13689219 2839488..2840906 1 NC_018650.1 COG0174 Glutamine synthetase; gamma-glutamylputrescine synthetase 2840906 13689219 O3M_13820 Escherichia coli O104:H4 str. 2009EL-2050 gamma-glutamylputrescine synthetase YP_006770404.1 2839488 D 1134782 CDS YP_006770405.1 410482859 13689220 2841209..2842594 1 NC_018650.1 COG0531 Amino acid transporters; putrescine importer 2842594 13689220 O3M_13825 Escherichia coli O104:H4 str. 2009EL-2050 putrescine importer YP_006770405.1 2841209 D 1134782 CDS YP_006770406.1 410482860 13689221 2842728..2842973 1 NC_018650.1 hypothetical protein 2842973 13689221 O3M_13830 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770406.1 2842728 D 1134782 CDS YP_006770407.1 410482861 13689222 2843285..2844928 1 NC_018650.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; antimicrobial peptide ABC transporter substrate-binding protein SapA 2844928 13689222 O3M_13835 Escherichia coli O104:H4 str. 2009EL-2050 antimicrobial peptide ABC transporter substrate-binding protein SapA YP_006770407.1 2843285 D 1134782 CDS YP_006770408.1 410482862 13689223 2844925..2845890 1 NC_018650.1 COG4168 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease SapB 2845890 13689223 O3M_13840 Escherichia coli O104:H4 str. 2009EL-2050 antimicrobial peptide ABC transporter permease SapB YP_006770408.1 2844925 D 1134782 CDS YP_006770409.1 410482863 13689224 2845877..2846767 1 NC_018650.1 COG4171 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease SapC 2846767 13689224 O3M_13845 Escherichia coli O104:H4 str. 2009EL-2050 antimicrobial peptide ABC transporter permease SapC YP_006770409.1 2845877 D 1134782 CDS YP_006770410.1 410482864 13689225 2846767..2847759 1 NC_018650.1 COG4170 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATP-binding protein 2847759 13689225 O3M_13850 Escherichia coli O104:H4 str. 2009EL-2050 antimicrobial peptide ABC transporter ATP-binding protein YP_006770410.1 2846767 D 1134782 CDS YP_006770411.1 410482865 13689226 2847761..2848567 1 NC_018650.1 COG4167 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATP-binding protein SapF 2848567 13689226 O3M_13855 Escherichia coli O104:H4 str. 2009EL-2050 antimicrobial peptide ABC transporter ATP-binding protein SapF YP_006770411.1 2847761 D 1134782 CDS YP_006770412.1 410482866 13689227 2848635..2848988 1 NC_018650.1 COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 2848988 13689227 O3M_13860 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770412.1 2848635 D 1134782 CDS YP_006770413.1 410482867 13689228 2849358..2850146 1 NC_018650.1 COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); enoyl-ACP reductase 2850146 13689228 O3M_13865 Escherichia coli O104:H4 str. 2009EL-2050 enoyl-ACP reductase YP_006770413.1 2849358 D 1134782 CDS YP_006770414.1 410482868 13689229 2850291..2851418 1 NC_018650.1 COG2128 Uncharacterized conserved protein; oxidoreductase 2851418 13689229 O3M_13870 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770414.1 2850291 D 1134782 CDS YP_006770415.1 410482869 13689230 2851486..2853420 1 NC_018650.1 COG4776 Exoribonuclease II; exoribonuclease II 2853420 13689230 O3M_13875 Escherichia coli O104:H4 str. 2009EL-2050 exoribonuclease II YP_006770415.1 2851486 D 1134782 CDS YP_006770416.1 410482870 13689231 complement(2853498..2853602) 1 NC_018650.1 hypothetical protein 2853602 13689231 O3M_13880 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770416.1 2853498 R 1134782 CDS YP_006770417.1 410482871 13689232 2853656..2855641 1 NC_018650.1 COG2199 FOG: GGDEF domain; RNase II stability modulator 2855641 13689232 O3M_13885 Escherichia coli O104:H4 str. 2009EL-2050 RNase II stability modulator YP_006770417.1 2853656 D 1134782 CDS YP_006770418.1 410482872 13689233 2855788..2855961 1 NC_018650.1 hypothetical protein 2855961 13689233 O3M_13890 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770418.1 2855788 D 1134782 CDS YP_006770419.1 410482873 13689234 2856051..2856800 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptionel regulator 2856800 13689234 O3M_13895 Escherichia coli O104:H4 str. 2009EL-2050 DeoR family transcriptionel regulator YP_006770419.1 2856051 D 1134782 CDS YP_006770420.1 410482874 13689235 2857069..2857287 1 NC_018650.1 lipoprotein 2857287 13689235 O3M_13900 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770420.1 2857069 D 1134782 CDS YP_006770421.1 410482875 13689236 complement(2857413..2857739) 1 NC_018650.1 COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins; translation initiation factor Sui1 2857739 13689236 O3M_13905 Escherichia coli O104:H4 str. 2009EL-2050 translation initiation factor Sui1 YP_006770421.1 2857413 R 1134782 CDS YP_006770422.1 410482876 13689237 complement(2857739..2858476) 1 NC_018650.1 COG0284 Orotidine-5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 2858476 13689237 O3M_13910 Escherichia coli O104:H4 str. 2009EL-2050 orotidine 5'-phosphate decarboxylase YP_006770422.1 2857739 R 1134782 CDS YP_006770423.1 410482877 13689238 complement(2858669..2859838) 1 NC_018650.1 COG2956 Predicted N-acetylglucosaminyl transferase; hypothetical protein 2859838 13689238 O3M_13915 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770423.1 2858669 R 1134782 CDS YP_006770424.1 410482878 13689239 complement(2859845..2860153) 1 NC_018650.1 COG3771 Predicted membrane protein; hypothetical protein 2860153 13689239 O3M_13920 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770424.1 2859845 R 1134782 CDS YP_006770425.1 410482879 13689240 complement(2860302..2861066) 1 NC_018650.1 COG0671 Membrane-associated phospholipid phosphatase; phosphatidylglycerophosphatase B 2861066 13689240 O3M_13925 Escherichia coli O104:H4 str. 2009EL-2050 phosphatidylglycerophosphatase B YP_006770425.1 2860302 R 1134782 CDS YP_006770426.1 410482880 13689241 2861236..2861826 1 NC_018650.1 COG0807 GTP cyclohydrolase II; GTP cyclohydrolase II 2861826 ribA 13689241 ribA Escherichia coli O104:H4 str. 2009EL-2050 GTP cyclohydrolase II YP_006770426.1 2861236 D 1134782 CDS YP_006770427.1 410482881 13689242 complement(2861890..2864565) 1 NC_018650.1 COG1048 Aconitase A; aconitate hydratase 2864565 13689242 O3M_13935 Escherichia coli O104:H4 str. 2009EL-2050 aconitate hydratase YP_006770427.1 2861890 R 1134782 CDS YP_006770428.1 410482882 13689243 2864739..2864864 1 NC_018650.1 hypothetical protein 2864864 13689243 O3M_13940 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770428.1 2864739 D 1134782 CDS YP_006770429.1 410482883 13689244 complement(2864938..2865105) 1 NC_018650.1 hypothetical protein 2865105 13689244 O3M_13945 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770429.1 2864938 R 1134782 CDS YP_006770430.1 410482884 13689245 complement(2865108..2865236) 1 NC_018650.1 hypothetical protein 2865236 13689245 O3M_13950 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770430.1 2865108 R 1134782 CDS YP_006770431.1 410482885 13689246 complement(2865566..2866540) 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional regulator CysB 2866540 cysB 13689246 cysB Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator CysB YP_006770431.1 2865566 R 1134782 CDS YP_006770432.1 410482886 13689247 complement(2866750..2869347) 1 NC_018650.1 COG0550 Topoisomerase IA; DNA topoisomerase I subunit omega 2869347 13689247 O3M_13960 Escherichia coli O104:H4 str. 2009EL-2050 DNA topoisomerase I subunit omega YP_006770432.1 2866750 R 1134782 CDS YP_006770433.1 410482887 13689248 2869727..2869978 1 NC_018650.1 hypothetical protein 2869978 13689248 O3M_13965 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770433.1 2869727 D 1134782 CDS YP_006770434.1 410482888 13689249 complement(2870014..2871063) 1 NC_018650.1 COG0616 Periplasmic serine proteases (ClpP class); inner membrane peptidase 2871063 13689249 O3M_13970 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane peptidase YP_006770434.1 2870014 R 1134782 CDS YP_006770435.1 410482889 13689250 2871283..2872041 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxoacyl-(acyl carrier protein) reductase 2872041 13689250 O3M_13975 Escherichia coli O104:H4 str. 2009EL-2050 oxoacyl-(acyl carrier protein) reductase YP_006770435.1 2871283 D 1134782 CDS YP_006770436.1 410482890 13689251 2872038..2872628 1 NC_018650.1 COG2109 ATP:corrinoid adenosyltransferase; cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase 2872628 13689251 O3M_13980 Escherichia coli O104:H4 str. 2009EL-2050 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase YP_006770436.1 2872038 D 1134782 CDS YP_006770437.1 410482891 13689252 complement(2872668..2873540) 1 NC_018650.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridylate synthase B 2873540 13689252 O3M_13985 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA pseudouridylate synthase B YP_006770437.1 2872668 R 1134782 CDS YP_006770438.1 410482892 13689253 complement(2873641..2874261) 1 NC_018650.1 COG0009 Putative translation factor (SUA5); hypothetical protein 2874261 13689253 O3M_13990 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770438.1 2873641 R 1134782 CDS YP_006770439.1 410482893 13689254 complement(2874258..2875139) 1 NC_018650.1 COG0613 Predicted metal-dependent phosphoesterases (PHP family); hypothetical protein 2875139 13689254 O3M_13995 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770439.1 2874258 R 1134782 CDS YP_006770440.1 410482894 13689255 2875413..2876975 1 NC_018650.1 COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate synthase component I 2876975 13689255 O3M_14000 Escherichia coli O104:H4 str. 2009EL-2050 anthranilate synthase component I YP_006770440.1 2875413 D 1134782 CDS YP_006770441.1 410482895 13689256 2876975..2878570 1 NC_018650.1 COG0512 Anthranilate/para-aminobenzoate synthases component II; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 2878570 13689256 O3M_14005 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_006770441.1 2876975 D 1134782 CDS YP_006770442.1 410482896 13689257 2878574..2879932 1 NC_018650.1 COG0134 Indole-3-glycerol phosphate synthase; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 2879932 13689257 O3M_14010 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_006770442.1 2878574 D 1134782 CDS YP_006770443.1 410482897 13689258 2879944..2881137 1 NC_018650.1 COG0133 Tryptophan synthase beta chain; tryptophan synthase subunit beta 2881137 13689258 O3M_14015 Escherichia coli O104:H4 str. 2009EL-2050 tryptophan synthase subunit beta YP_006770443.1 2879944 D 1134782 CDS YP_006770444.1 410482898 13689259 2881137..2881943 1 NC_018650.1 COG0159 Tryptophan synthase alpha chain; tryptophan synthase subunit alpha 2881943 trpA 13689259 trpA Escherichia coli O104:H4 str. 2009EL-2050 tryptophan synthase subunit alpha YP_006770444.1 2881137 D 1134782 CDS YP_006770445.1 410482899 13689260 2882589..2883089 1 NC_018650.1 COG3685 Uncharacterized protein conserved in bacteria; YciF protein 2883089 13689260 O3M_14025 Escherichia coli O104:H4 str. 2009EL-2050 YciF protein YP_006770445.1 2882589 D 1134782 CDS YP_006770446.1 410482900 13689261 2883135..2883641 1 NC_018650.1 COG3685 Uncharacterized protein conserved in bacteria; hypothetical protein 2883641 13689261 O3M_14030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770446.1 2883135 D 1134782 CDS YP_006770447.1 410482901 13689262 complement(2884130..2884300) 1 NC_018650.1 tail component 2884300 13689262 O3M_14035 Escherichia coli O104:H4 str. 2009EL-2050 tail component YP_006770447.1 2884130 R 1134782 CDS YP_006770448.1 410482902 13689263 complement(2884415..2884684) 1 NC_018650.1 tail fiber assembly protein 2884684 13689263 O3M_14040 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber assembly protein YP_006770448.1 2884415 R 1134782 CDS YP_006770449.1 410482903 13689264 2884753..2885409 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 2885409 13689264 O3M_14045 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770449.1 2884753 D 1134782 CDS YP_006770450.1 410482904 13689265 complement(2885464..2886048) 1 NC_018650.1 Qin prophage; tail fiber chaperone 2886048 13689265 O3M_14050 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber chaperone YP_006770450.1 2885464 R 1134782 CDS YP_006770451.1 410482905 13689266 complement(2886048..2888882) 1 NC_018650.1 phage tail fiber protein 2888882 13689266 O3M_14055 Escherichia coli O104:H4 str. 2009EL-2050 phage tail fiber protein YP_006770451.1 2886048 R 1134782 CDS YP_006770452.1 410482906 13689267 complement(2889034..2889633) 1 NC_018650.1 outer membrane Lom 2889633 13689267 O3M_14060 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane Lom YP_006770452.1 2889034 R 1134782 CDS YP_006770453.1 410482907 13689268 complement(2889701..2893180) 1 NC_018650.1 COG4733 Phage-related protein, tail component; Host specificity protein J 2893180 13689268 O3M_14065 Escherichia coli O104:H4 str. 2009EL-2050 Host specificity protein J YP_006770453.1 2889701 R 1134782 CDS YP_006770454.1 410482908 13689269 complement(2893659..2894300) 1 NC_018650.1 COG4723 Phage-related protein, tail component; Tail assembly protein I from prophage 2894300 13689269 O3M_14070 Escherichia coli O104:H4 str. 2009EL-2050 Tail assembly protein I from prophage YP_006770454.1 2893659 R 1134782 CDS YP_006770455.1 410482909 13689270 complement(2894198..2894941) 1 NC_018650.1 COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; tail fiber component K of prophage 2894941 13689270 O3M_14075 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber component K of prophage YP_006770455.1 2894198 R 1134782 CDS YP_006770456.1 410482910 13689271 complement(2894946..2895644) 1 NC_018650.1 COG4672 Phage-related protein; minor tail protein L 2895644 13689271 O3M_14080 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein L YP_006770456.1 2894946 R 1134782 CDS YP_006770457.1 410482911 13689272 complement(2895644..2895973) 1 NC_018650.1 COG4718 Phage-related protein; minor tail protein M 2895973 13689272 O3M_14085 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein M YP_006770457.1 2895644 R 1134782 CDS YP_006770458.1 410482912 13689273 complement(2895970..2898543) 1 NC_018650.1 COG5281 Phage-related minor tail protein; minor tail protein H 2898543 13689273 O3M_14090 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein H YP_006770458.1 2895970 R 1134782 CDS YP_006770459.1 410482913 13689274 complement(2898524..2898937) 1 NC_018650.1 tail protein 2898937 13689274 O3M_14095 Escherichia coli O104:H4 str. 2009EL-2050 tail protein YP_006770459.1 2898524 R 1134782 CDS YP_006770460.1 410482914 13689275 complement(2898964..2899395) 1 NC_018650.1 minor tail protein G 2899395 13689275 O3M_14100 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein G YP_006770460.1 2898964 R 1134782 CDS YP_006770461.1 410482915 13689276 complement(2899409..2900161) 1 NC_018650.1 COG5492 Bacterial surface proteins containing Ig-like domains; major tail protein V 2900161 13689276 O3M_14105 Escherichia coli O104:H4 str. 2009EL-2050 major tail protein V YP_006770461.1 2899409 R 1134782 CDS YP_006770462.1 410482916 13689277 complement(2900169..2900564) 1 NC_018650.1 minor tail protein 2900564 13689277 O3M_14110 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein YP_006770462.1 2900169 R 1134782 CDS YP_006770463.1 410482917 13689278 complement(2900561..2901136) 1 NC_018650.1 minor tail protein Z (GpZ) 2901136 13689278 O3M_14115 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein Z (GpZ) YP_006770463.1 2900561 R 1134782 CDS YP_006770464.1 410482918 13689279 complement(2901151..2901504) 1 NC_018650.1 Tail attachment protein (Minor capsid protein FII) 2901504 13689279 O3M_14120 Escherichia coli O104:H4 str. 2009EL-2050 Tail attachment protein (Minor capsid protein FII) YP_006770464.1 2901151 R 1134782 CDS YP_006770465.1 410482919 13689280 complement(2901497..2901865) 1 NC_018650.1 DNA packaging protein from phage origin 2901865 13689280 O3M_14125 Escherichia coli O104:H4 str. 2009EL-2050 DNA packaging protein from phage origin YP_006770465.1 2901497 R 1134782 CDS YP_006770466.1 410482920 13689281 complement(2901917..2902945) 1 NC_018650.1 major head protein 2902945 13689281 O3M_14130 Escherichia coli O104:H4 str. 2009EL-2050 major head protein YP_006770466.1 2901917 R 1134782 CDS YP_006770467.1 410482921 13689282 complement(2903003..2903350) 1 NC_018650.1 head-DNA stabilization protein 2903350 13689282 O3M_14135 Escherichia coli O104:H4 str. 2009EL-2050 head-DNA stabilization protein YP_006770467.1 2903003 R 1134782 CDS YP_006770468.1 410482922 13689283 complement(2903387..2904892) 1 NC_018650.1 COG0616 Periplasmic serine proteases (ClpP class); Head-tail preconnector protein GP5 (Contains: Scaffold protein GP6 (Head protein GP6)) 2904892 13689283 O3M_14140 Escherichia coli O104:H4 str. 2009EL-2050 Head-tail preconnector protein GP5 (Contains: Scaffold protein GP6 (Head protein GP6)) YP_006770468.1 2903387 R 1134782 CDS YP_006770469.1 410482923 13689284 complement(2904882..2906474) 1 NC_018650.1 COG5511 Bacteriophage capsid protein; portal protein 2906474 13689284 O3M_14145 Escherichia coli O104:H4 str. 2009EL-2050 portal protein YP_006770469.1 2904882 R 1134782 CDS YP_006770470.1 410482924 13689285 complement(2906471..2906677) 1 NC_018650.1 head completion protein 2906677 13689285 O3M_14150 Escherichia coli O104:H4 str. 2009EL-2050 head completion protein YP_006770470.1 2906471 R 1134782 CDS YP_006770471.1 410482925 13689286 complement(2906661..2907059) 1 NC_018650.1 COG5525 Bacteriophage tail assembly protein; terminase large subunit (Gp2) 2907059 13689286 O3M_14155 Escherichia coli O104:H4 str. 2009EL-2050 terminase large subunit (Gp2) YP_006770471.1 2906661 R 1134782 CDS YP_006770472.1 410482926 13689287 complement(2907046..2908590) 1 NC_018650.1 COG5525 Bacteriophage tail assembly protein; Terminase large subunit (Gp2) 2908590 13689287 O3M_14160 Escherichia coli O104:H4 str. 2009EL-2050 Terminase large subunit (Gp2) YP_006770472.1 2907046 R 1134782 CDS YP_006770473.1 410482927 13689288 complement(2908562..2909110) 1 NC_018650.1 COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; prophage Qin DNA packaging protein NU1-like protein 2909110 13689288 O3M_14165 Escherichia coli O104:H4 str. 2009EL-2050 prophage Qin DNA packaging protein NU1-like protein YP_006770473.1 2908562 R 1134782 CDS YP_006770474.1 410482928 13689289 complement(2909192..2909464) 1 NC_018650.1 hypothetical protein 2909464 13689289 O3M_14170 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770474.1 2909192 R 1134782 CDS YP_006770475.1 410482929 13689290 complement(2909511..2909915) 1 NC_018650.1 hypothetical protein 2909915 13689290 O3M_14175 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770475.1 2909511 R 1134782 CDS YP_006770476.1 410482930 13689291 complement(2910051..2910275) 1 NC_018650.1 hypothetical protein 2910275 13689291 O3M_14180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770476.1 2910051 R 1134782 CDS YP_006770477.1 410482931 13689292 complement(2910369..2910656) 1 NC_018650.1 hypothetical protein 2910656 13689292 O3M_14185 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770477.1 2910369 R 1134782 CDS YP_006770478.1 410482932 13689293 complement(2910735..2910878) 1 NC_018650.1 hypothetical protein 2910878 13689293 O3M_14190 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770478.1 2910735 R 1134782 CDS YP_006770479.1 410482933 13689294 complement(2910875..2911342) 1 NC_018650.1 endopeptidase 2911342 13689294 O3M_14195 Escherichia coli O104:H4 str. 2009EL-2050 endopeptidase YP_006770479.1 2910875 R 1134782 CDS YP_006770480.1 410482934 13689295 complement(2911442..2911657) 1 NC_018650.1 hypothetical protein 2911657 13689295 O3M_14200 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770480.1 2911442 R 1134782 CDS YP_006770481.1 410482935 13689296 complement(2911695..2911907) 1 NC_018650.1 COG5178 U5 snRNP spliceosome subunit; hypothetical protein 2911907 13689296 O3M_14205 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770481.1 2911695 R 1134782 CDS YP_006770482.1 410482936 13689297 complement(2911985..2912518) 1 NC_018650.1 COG3772 Phage-related lysozyme (muraminidase); phage-related lysozyme (muraminidase) 2912518 13689297 O3M_14210 Escherichia coli O104:H4 str. 2009EL-2050 phage-related lysozyme (muraminidase) YP_006770482.1 2911985 R 1134782 CDS YP_006770483.1 410482937 13689298 complement(2912561..2913367) 1 NC_018650.1 phage protein 2913367 13689298 O3M_14215 Escherichia coli O104:H4 str. 2009EL-2050 phage protein YP_006770483.1 2912561 R 1134782 CDS YP_006770484.1 410482938 13689299 complement(2913372..2913587) 1 NC_018650.1 lysis protein S of prophage CP-933V 2913587 13689299 O3M_14220 Escherichia coli O104:H4 str. 2009EL-2050 lysis protein S of prophage CP-933V YP_006770484.1 2913372 R 1134782 CDS YP_006770485.1 410482939 13689300 complement(2913738..2915591) 1 NC_018650.1 prophage protein 2915591 13689300 O3M_14225 Escherichia coli O104:H4 str. 2009EL-2050 prophage protein YP_006770485.1 2913738 R 1134782 CDS YP_006770486.1 410482940 13689301 2915864..2916187 1 NC_018650.1 anti-adapter protein IraM 2916187 13689301 O3M_14230 Escherichia coli O104:H4 str. 2009EL-2050 anti-adapter protein IraM YP_006770486.1 2915864 D 1134782 CDS YP_006770487.1 410482941 13689302 complement(2916635..2916913) 1 NC_018650.1 hypothetical protein 2916913 13689302 O3M_14235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770487.1 2916635 R 1134782 CDS YP_006770488.1 410482942 13689306 complement(2917398..2918447) 1 NC_018650.1 COG0863 DNA modification methylase; DNA adenine methyltransferase ( DNA methylase) from phage origin 2918447 13689306 O3M_14240 Escherichia coli O104:H4 str. 2009EL-2050 DNA adenine methyltransferase ( DNA methylase) from phage origin YP_006770488.1 2917398 R 1134782 CDS YP_006770489.1 410482943 13689307 complement(2918598..2918795) 1 NC_018650.1 hypothetical protein 2918795 13689307 O3M_14245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770489.1 2918598 R 1134782 CDS YP_006770490.1 410482944 13689308 complement(2919022..2919843) 1 NC_018650.1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; antitermination protein Q of prophage 2919843 13689308 O3M_14250 Escherichia coli O104:H4 str. 2009EL-2050 antitermination protein Q of prophage YP_006770490.1 2919022 R 1134782 CDS YP_006770491.1 410482945 13689309 complement(2919840..2920214) 1 NC_018650.1 COG4570 Holliday junction resolvase; holliday junction resolvase 2920214 13689309 O3M_14255 Escherichia coli O104:H4 str. 2009EL-2050 holliday junction resolvase YP_006770491.1 2919840 R 1134782 CDS YP_006770492.1 410482946 13689310 complement(2920227..2921273) 1 NC_018650.1 hypothetical protein 2921273 13689310 O3M_14260 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770492.1 2920227 R 1134782 CDS YP_006770493.1 410482947 13689311 2921494..2921673 1 NC_018650.1 hypothetical protein 2921673 13689311 O3M_14265 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770493.1 2921494 D 1134782 CDS YP_006770494.1 410482948 13689312 complement(2921715..2921927) 1 NC_018650.1 cell killing protein encoded within cryptic prophage CP-933M 2921927 13689312 O3M_14270 Escherichia coli O104:H4 str. 2009EL-2050 cell killing protein encoded within cryptic prophage CP-933M YP_006770494.1 2921715 R 1134782 CDS YP_006770495.1 410482949 13689313 complement(2922108..2922794) 1 NC_018650.1 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein 2922794 13689313 O3M_14275 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770495.1 2922108 R 1134782 CDS YP_006770496.1 410482950 13689314 complement(2922948..2923373) 1 NC_018650.1 phage protein 2923373 13689314 O3M_14280 Escherichia coli O104:H4 str. 2009EL-2050 phage protein YP_006770496.1 2922948 R 1134782 CDS YP_006770497.1 410482951 13689315 complement(2923414..2924376) 1 NC_018650.1 replication protein 2924376 13689315 O3M_14285 Escherichia coli O104:H4 str. 2009EL-2050 replication protein YP_006770497.1 2923414 R 1134782 CDS YP_006770498.1 410482952 13689316 complement(2924399..2924824) 1 NC_018650.1 phage regulatory protein CII 2924824 13689316 O3M_14290 Escherichia coli O104:H4 str. 2009EL-2050 phage regulatory protein CII YP_006770498.1 2924399 R 1134782 CDS YP_006770499.1 410482953 13689317 complement(2924821..2925075) 1 NC_018650.1 regulatory protein 2925075 13689317 O3M_14295 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein YP_006770499.1 2924821 R 1134782 CDS YP_006770500.1 410482954 13689318 2925155..2925574 1 NC_018650.1 COG1396 Predicted transcriptional regulators; phage repressor protein CI 2925574 13689318 O3M_14300 Escherichia coli O104:H4 str. 2009EL-2050 phage repressor protein CI YP_006770500.1 2925155 D 1134782 CDS YP_006770501.1 410482955 13689319 2925871..2926023 1 NC_018650.1 hypothetical protein 2926023 13689319 O3M_14305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770501.1 2925871 D 1134782 CDS YP_006770502.1 410482956 13689320 2926035..2926373 1 NC_018650.1 hypothetical protein 2926373 13689320 O3M_14310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770502.1 2926035 D 1134782 CDS YP_006770503.1 410482957 13689321 complement(2926362..2926556) 1 NC_018650.1 hypothetical protein 2926556 13689321 O3M_14315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770503.1 2926362 R 1134782 CDS YP_006770504.1 410482958 13689322 2927123..2927311 1 NC_018650.1 regulator of cell division encoded by prophage 2927311 13689322 O3M_14320 Escherichia coli O104:H4 str. 2009EL-2050 regulator of cell division encoded by prophage YP_006770504.1 2927123 D 1134782 CDS YP_006770505.1 410482959 13689323 2927308..2927499 1 NC_018650.1 hypothetical protein 2927499 13689323 O3M_14325 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770505.1 2927308 D 1134782 CDS YP_006770506.1 410482960 13689324 2927592..2930063 1 NC_018650.1 exonuclease from phage origin 2930063 13689324 O3M_14330 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease from phage origin YP_006770506.1 2927592 D 1134782 CDS YP_006770507.1 410482961 13689325 2930128..2930376 1 NC_018650.1 excisionase 2930376 13689325 O3M_14335 Escherichia coli O104:H4 str. 2009EL-2050 excisionase YP_006770507.1 2930128 D 1134782 CDS YP_006770508.1 410482962 13689326 2930354..2931484 1 NC_018650.1 COG0582 Integrase; integrase 2931484 13689326 O3M_14340 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006770508.1 2930354 D 1134782 CDS YP_006770509.1 410482963 13689327 complement(2931530..2932168) 1 NC_018650.1 COG3047 Outer membrane protein W; outer membrane protein W 2932168 13689327 O3M_14345 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein W YP_006770509.1 2931530 R 1134782 CDS YP_006770510.1 410482964 13689328 2932525..2933268 1 NC_018650.1 hypothetical protein 2933268 13689328 O3M_14350 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770510.1 2932525 D 1134782 CDS YP_006770511.1 410482965 13689329 2933298..2933837 1 NC_018650.1 COG2917 Intracellular septation protein A; intracellular septation protein A 2933837 13689329 O3M_14355 Escherichia coli O104:H4 str. 2009EL-2050 intracellular septation protein A YP_006770511.1 2933298 D 1134782 CDS YP_006770512.1 410482966 13689330 2933942..2934340 1 NC_018650.1 COG1607 Acyl-CoA hydrolase; acyl-CoA esterase 2934340 13689330 O3M_14360 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA esterase YP_006770512.1 2933942 D 1134782 CDS YP_006770513.1 410482967 13689331 complement(2934380..2935099) 1 NC_018650.1 COG0810 Periplasmic protein TonB, links inner and outer membranes; transporter 2935099 13689331 O3M_14365 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770513.1 2934380 R 1134782 CDS YP_006770514.1 410482968 13689332 2935323..2935619 1 NC_018650.1 COG2350 Uncharacterized protein conserved in bacteria; YciI-like protein 2935619 13689332 O3M_14370 Escherichia coli O104:H4 str. 2009EL-2050 YciI-like protein YP_006770514.1 2935323 D 1134782 CDS YP_006770515.1 410482969 13689333 2935919..2937172 1 NC_018650.1 COG1226 Kef-type K+ transport systems, predicted NAD-binding component; voltage-gated potassium channel 2937172 13689333 O3M_14375 Escherichia coli O104:H4 str. 2009EL-2050 voltage-gated potassium channel YP_006770515.1 2935919 D 1134782 CDS YP_006770516.1 410482970 13689334 2937543..2939003 1 NC_018650.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; cardiolipin synthetase 2939003 cls 13689334 cls Escherichia coli O104:H4 str. 2009EL-2050 cardiolipin synthetase YP_006770516.1 2937543 D 1134782 CDS YP_006770517.1 410482971 13689335 2939038..2939367 1 NC_018650.1 COG3099 Uncharacterized protein conserved in bacteria; dsDNA-mimic protein 2939367 13689335 O3M_14385 Escherichia coli O104:H4 str. 2009EL-2050 dsDNA-mimic protein YP_006770517.1 2939038 D 1134782 CDS YP_006770518.1 410482972 13689336 complement(2939420..2940424) 1 NC_018650.1 COG4608 ABC-type oligopeptide transport system, ATPase component; oligopeptide ABC transporter ATP-binding protein OppF 2940424 13689336 O3M_14390 Escherichia coli O104:H4 str. 2009EL-2050 oligopeptide ABC transporter ATP-binding protein OppF YP_006770518.1 2939420 R 1134782 CDS YP_006770519.1 410482973 13689337 complement(2940421..2941434) 1 NC_018650.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; oligopeptide ABC transporter ATP-binding protein 2941434 oppD 13689337 oppD Escherichia coli O104:H4 str. 2009EL-2050 oligopeptide ABC transporter ATP-binding protein YP_006770519.1 2940421 R 1134782 CDS YP_006770520.1 410482974 13689338 complement(2941446..2942354) 1 NC_018650.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; oligopeptide ABC transporter permease OppC 2942354 13689338 O3M_14400 Escherichia coli O104:H4 str. 2009EL-2050 oligopeptide ABC transporter permease OppC YP_006770520.1 2941446 R 1134782 CDS YP_006770521.1 410482975 13689339 complement(2942369..2943289) 1 NC_018650.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; oligopeptide transporter permease 2943289 oppB 13689339 oppB Escherichia coli O104:H4 str. 2009EL-2050 oligopeptide transporter permease YP_006770521.1 2942369 R 1134782 CDS YP_006770522.1 410482976 13689340 complement(2943375..2945006) 1 NC_018650.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein OppA 2945006 13689340 O3M_14410 Escherichia coli O104:H4 str. 2009EL-2050 oligopeptide ABC transporter substrate-binding protein OppA YP_006770522.1 2943375 R 1134782 CDS YP_006770523.1 410482977 13689341 complement(2945744..2946391) 1 NC_018650.1 COG2095 Multiple antibiotic transporter; hypothetical protein 2946391 13689341 O3M_14415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770523.1 2945744 R 1134782 CDS YP_006770524.1 410482978 13689342 2946868..2949543 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2949543 13689342 O3M_14420 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_006770524.1 2946868 D 1134782 CDS YP_006770525.1 410482979 13689343 complement(2950849..2951466) 1 NC_018650.1 COG1435 Thymidine kinase; thymidine kinase 2951466 13689343 O3M_14440 Escherichia coli O104:H4 str. 2009EL-2050 thymidine kinase YP_006770525.1 2950849 R 1134782 CDS YP_006770526.1 410482980 13689344 2952072..2952485 1 NC_018650.1 COG2916 DNA-binding protein H-NS; global DNA-binding transcriptional dual regulator H-NS 2952485 13689344 O3M_14445 Escherichia coli O104:H4 str. 2009EL-2050 global DNA-binding transcriptional dual regulator H-NS YP_006770526.1 2952072 D 1134782 CDS YP_006770527.1 410482981 13689345 complement(2952629..2953537) 1 NC_018650.1 COG1210 UDP-glucose pyrophosphorylase; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 2953537 13689345 O3M_14450 Escherichia coli O104:H4 str. 2009EL-2050 UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_006770527.1 2952629 R 1134782 CDS YP_006770528.1 410482982 13689346 complement(2953739..2954752) 1 NC_018650.1 COG0784 FOG: CheY-like receiver; response regulator of RpoS 2954752 13689346 O3M_14455 Escherichia coli O104:H4 str. 2009EL-2050 response regulator of RpoS YP_006770528.1 2953739 R 1134782 CDS YP_006770529.1 410482983 13689347 complement(2954844..2955749) 1 NC_018650.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein 2955749 13689347 O3M_14460 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770529.1 2954844 R 1134782 CDS YP_006770530.1 410482984 13689348 2955862..2956320 1 NC_018650.1 COG3012 Uncharacterized protein conserved in bacteria; hypothetical protein 2956320 13689348 O3M_14465 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770530.1 2955862 D 1134782 CDS YP_006770531.1 410482985 13689349 2956370..2957212 1 NC_018650.1 COG0788 Formyltetrahydrofolate hydrolase; formyltetrahydrofolate deformylase 2957212 purU 13689349 purU Escherichia coli O104:H4 str. 2009EL-2050 formyltetrahydrofolate deformylase YP_006770531.1 2956370 D 1134782 CDS YP_006770532.1 410482986 13689352 complement(2957937..2958614) 1 NC_018650.1 COG2181 Nitrate reductase gamma subunit; Respiratory nitrate reductase subunit gamma 2958614 13689352 O3M_14485 Escherichia coli O104:H4 str. 2009EL-2050 Respiratory nitrate reductase subunit gamma YP_006770532.1 2957937 R 1134782 CDS YP_006770533.1 410482987 13689353 complement(2958614..2959324) 1 NC_018650.1 COG2180 Nitrate reductase delta subunit; molybdenum-cofactor-assembly chaperone subunit delta 2959324 13689353 O3M_14490 Escherichia coli O104:H4 str. 2009EL-2050 molybdenum-cofactor-assembly chaperone subunit delta YP_006770533.1 2958614 R 1134782 CDS YP_006770534.1 410482988 13689354 complement(2959321..2960859) 1 NC_018650.1 COG1140 Nitrate reductase beta subunit; nitrate reductase subunit beta 2960859 13689354 O3M_14495 Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase subunit beta YP_006770534.1 2959321 R 1134782 CDS YP_006770535.1 410482989 13689355 complement(2960856..2964599) 1 NC_018650.1 COG5013 Nitrate reductase alpha subunit; nitrate reductase subunit alpha 2964599 13689355 O3M_14500 Escherichia coli O104:H4 str. 2009EL-2050 nitrate reductase subunit alpha YP_006770535.1 2960856 R 1134782 CDS YP_006770536.1 410482990 13689356 complement(2965115..2966506) 1 NC_018650.1 COG2223 Nitrate/nitrite transporter; nitrite extrusion protein 2966506 13689356 O3M_14505 Escherichia coli O104:H4 str. 2009EL-2050 nitrite extrusion protein YP_006770536.1 2965115 R 1134782 CDS YP_006770537.1 410482991 13689357 2966845..2968641 1 NC_018650.1 COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific; nitrate/nitrite sensor protein NarX 2968641 13689357 O3M_14510 Escherichia coli O104:H4 str. 2009EL-2050 nitrate/nitrite sensor protein NarX YP_006770537.1 2966845 D 1134782 CDS YP_006770538.1 410482992 13689358 2968634..2969284 1 NC_018650.1 two-component regulatory system; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding response regulator NarL/sensory histidine kinase NarX 2969284 13689358 O3M_14515 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding response regulator NarL/sensory histidine kinase NarX YP_006770538.1 2968634 D 1134782 CDS YP_006770539.1 410482993 13689359 complement(2969285..2970538) 1 NC_018650.1 invasin 2970538 13689359 O3M_14520 Escherichia coli O104:H4 str. 2009EL-2050 invasin YP_006770539.1 2969285 R 1134782 CDS YP_006770540.1 410482994 13689360 2970864..2971217 1 NC_018650.1 COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction; hypothetical protein 2971217 13689360 O3M_14525 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770540.1 2970864 D 1134782 CDS YP_006770541.1 410482995 13689361 complement(2971261..2971977) 1 NC_018650.1 COG3703 Uncharacterized protein involved in cation transport; regulatory protein for cation transport 2971977 13689361 O3M_14530 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein for cation transport YP_006770541.1 2971261 R 1134782 CDS YP_006770542.1 410482996 13689362 complement(2972114..2972344) 1 NC_018650.1 COG4572 Putative cation transport regulator; cation transport regulator 2972344 chaB 13689362 chaB Escherichia coli O104:H4 str. 2009EL-2050 cation transport regulator YP_006770542.1 2972114 R 1134782 CDS YP_006770543.1 410482997 13689363 2972614..2973714 1 NC_018650.1 COG0387 Ca2+/H+ antiporter; calcium/sodium:proton antiporter 2973714 13689363 O3M_14540 Escherichia coli O104:H4 str. 2009EL-2050 calcium/sodium:proton antiporter YP_006770543.1 2972614 D 1134782 CDS YP_006770544.1 410482998 13689364 2974119..2974226 1 NC_018650.1 hypothetical protein 2974226 13689364 O3M_14545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770544.1 2974119 D 1134782 CDS YP_006770545.1 410482999 13689365 2974654..2974761 1 NC_018650.1 hypothetical protein 2974761 13689365 O3M_14550 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770545.1 2974654 D 1134782 CDS YP_006770546.1 410483000 13689366 complement(2974910..2975764) 1 NC_018650.1 COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; 2-dehydro-3-deoxyphosphooctonate aldolase 2975764 13689366 O3M_14555 Escherichia coli O104:H4 str. 2009EL-2050 2-dehydro-3-deoxyphosphooctonate aldolase YP_006770546.1 2974910 R 1134782 CDS YP_006770547.1 410483001 13689367 complement(2975800..2976609) 1 NC_018650.1 COG2912 Uncharacterized conserved protein; hypothetical protein 2976609 13689367 O3M_14560 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770547.1 2975800 R 1134782 CDS YP_006770548.1 410483002 13689368 complement(2976613..2977005) 1 NC_018650.1 COG3094 Uncharacterized protein conserved in bacteria; hypothetical protein 2977005 13689368 O3M_14565 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770548.1 2976613 R 1134782 CDS YP_006770549.1 410483003 13689369 complement(2977002..2977835) 1 NC_018650.1 COG2890 Methylase of polypeptide chain release factors; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2977835 13689369 O3M_14570 Escherichia coli O104:H4 str. 2009EL-2050 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_006770549.1 2977002 R 1134782 CDS YP_006770550.1 410483004 13689370 complement(2977835..2978917) 1 NC_018650.1 COG0216 Protein chain release factor A; peptide chain release factor 1 2978917 prfA 13689370 prfA Escherichia coli O104:H4 str. 2009EL-2050 peptide chain release factor 1 YP_006770550.1 2977835 R 1134782 CDS YP_006770551.1 410483005 13689371 complement(2978959..2980215) 1 NC_018650.1 COG0373 Glutamyl-tRNA reductase; glutamyl-tRNA reductase 2980215 hemA 13689371 hemA Escherichia coli O104:H4 str. 2009EL-2050 glutamyl-tRNA reductase YP_006770551.1 2978959 R 1134782 CDS YP_006770552.1 410483006 13689372 2980429..2981052 1 NC_018650.1 COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis; outer membrane lipoprotein LolB 2981052 lolB 13689372 lolB Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein LolB YP_006770552.1 2980429 D 1134782 CDS YP_006770553.1 410483007 13689373 2981052..2981903 1 NC_018650.1 COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2981903 ipk 13689373 ipk Escherichia coli O104:H4 str. 2009EL-2050 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_006770553.1 2981052 D 1134782 CDS YP_006770554.1 410483008 13689374 2982054..2983001 1 NC_018650.1 COG0462 Phosphoribosylpyrophosphate synthetase; ribose-phosphate pyrophosphokinase 2983001 13689374 O3M_14595 Escherichia coli O104:H4 str. 2009EL-2050 ribose-phosphate pyrophosphokinase YP_006770554.1 2982054 D 1134782 CDS YP_006770555.1 410483009 13689375 2983126..2984805 1 NC_018650.1 COG0659 Sulfate permease and related transporters (MFS superfamily); transporter 2984805 13689375 O3M_14600 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770555.1 2983126 D 1134782 CDS YP_006770556.1 410483010 13689376 complement(2984860..2985138) 1 NC_018650.1 hypothetical protein 2985138 13689376 O3M_14605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770556.1 2984860 R 1134782 CDS YP_006770557.1 410483011 13689377 2985416..2986000 1 NC_018650.1 COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 2986000 13689377 O3M_14610 Escherichia coli O104:H4 str. 2009EL-2050 peptidyl-tRNA hydrolase YP_006770557.1 2985416 D 1134782 CDS YP_006770558.1 410483012 13689378 2986117..2987208 1 NC_018650.1 COG0012 Predicted GTPase, probable translation factor; GTP-binding protein YchF 2987208 13689378 O3M_14615 Escherichia coli O104:H4 str. 2009EL-2050 GTP-binding protein YchF YP_006770558.1 2986117 D 1134782 CDS YP_006770559.1 410483013 13689379 complement(2987453..2987632) 1 NC_018650.1 hypothetical protein 2987632 13689379 O3M_14620 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770559.1 2987453 R 1134782 CDS YP_006770560.1 410483014 13689380 2987977..2990844 1 NC_018650.1 autotransporter; COG3468 Type V secretory pathway, adhesin AidA; adhesin 2990844 13689380 O3M_14625 Escherichia coli O104:H4 str. 2009EL-2050 adhesin YP_006770560.1 2987977 D 1134782 CDS YP_006770561.1 410483015 13689381 complement(2990944..2992863) 1 NC_018650.1 COG3284 Transcriptional activator of acetoin/glycerol metabolism; DNA-binding transcriptional regulator DhaR 2992863 13689381 O3M_14630 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator DhaR YP_006770561.1 2990944 R 1134782 CDS YP_006770562.1 410483016 13689382 2993091..2994161 1 NC_018650.1 COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 2994161 13689382 O3M_14635 Escherichia coli O104:H4 str. 2009EL-2050 dihydroxyacetone kinase subunit DhaK YP_006770562.1 2993091 D 1134782 CDS YP_006770563.1 410483017 13689383 2994172..2994804 1 NC_018650.1 COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaL 2994804 13689383 O3M_14640 Escherichia coli O104:H4 str. 2009EL-2050 dihydroxyacetone kinase subunit DhaL YP_006770563.1 2994172 D 1134782 CDS YP_006770564.1 410483018 13689384 2994815..2996233 1 NC_018650.1 COG3412 Uncharacterized protein conserved in bacteria; dihydroxyacetone kinase subunit DhaM 2996233 13689384 O3M_14645 Escherichia coli O104:H4 str. 2009EL-2050 dihydroxyacetone kinase subunit DhaM YP_006770564.1 2994815 D 1134782 CDS YP_006770565.1 410483019 13689385 2996553..2998250 1 NC_018650.1 COG1626 Neutral trehalase; trehalase 2998250 treA 13689385 treA Escherichia coli O104:H4 str. 2009EL-2050 trehalase YP_006770565.1 2996553 D 1134782 CDS YP_006770566.1 410483020 13689386 complement(2998329..2998769) 1 NC_018650.1 hypothetical protein 2998769 13689386 O3M_14655 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770566.1 2998329 R 1134782 CDS YP_006770567.1 410483021 13689387 complement(2998947..2999201) 1 NC_018650.1 COG2261 Predicted membrane protein; inner membrane protein with transglycosylase-associated domain 2999201 13689387 O3M_14660 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein with transglycosylase-associated domain YP_006770567.1 2998947 R 1134782 CDS YP_006770568.1 410483022 13689388 2999402..3000136 1 NC_018650.1 COG5581 Predicted glycosyltransferase; flagellar function protein 3000136 13689388 O3M_14665 Escherichia coli O104:H4 str. 2009EL-2050 flagellar function protein YP_006770568.1 2999402 D 1134782 CDS YP_006770569.1 410483023 13689389 complement(3000138..3000749) 1 NC_018650.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic murein endotransglycosylase E 3000749 emtA 13689389 emtA Escherichia coli O104:H4 str. 2009EL-2050 lytic murein endotransglycosylase E YP_006770569.1 3000138 R 1134782 CDS YP_006770570.1 410483024 13689390 3000849..3001763 1 NC_018650.1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; L,D-carboxypeptidase A 3001763 ldcA 13689390 ldcA Escherichia coli O104:H4 str. 2009EL-2050 L,D-carboxypeptidase A YP_006770570.1 3000849 D 1134782 CDS YP_006770571.1 410483025 13689391 3001858..3003594 1 NC_018650.1 COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain; potassium/proton antiporter 3003594 13689391 O3M_14680 Escherichia coli O104:H4 str. 2009EL-2050 potassium/proton antiporter YP_006770571.1 3001858 D 1134782 CDS YP_006770572.1 410483026 13689392 complement(3003980..3005050) 1 NC_018650.1 COG0787 Alanine racemase; alanine racemase 3005050 dadX 13689392 dadX Escherichia coli O104:H4 str. 2009EL-2050 alanine racemase YP_006770572.1 3003980 R 1134782 CDS YP_006770573.1 410483027 13689393 complement(3005060..3006358) 1 NC_018650.1 COG0665 Glycine/D-amino acid oxidases (deaminating); D-amino acid dehydrogenase small subunit 3006358 13689393 O3M_14690 Escherichia coli O104:H4 str. 2009EL-2050 D-amino acid dehydrogenase small subunit YP_006770573.1 3005060 R 1134782 CDS YP_006770574.1 410483028 13689394 3006688..3008220 1 NC_018650.1 COG2719 Uncharacterized conserved protein; SpoVR family protein 3008220 13689394 O3M_14695 Escherichia coli O104:H4 str. 2009EL-2050 SpoVR family protein YP_006770574.1 3006688 D 1134782 CDS YP_006770575.1 410483029 13689395 complement(3008272..3008991) 1 NC_018650.1 COG2186 Transcriptional regulators; fatty acid metabolism regulator 3008991 13689395 O3M_14700 Escherichia coli O104:H4 str. 2009EL-2050 fatty acid metabolism regulator YP_006770575.1 3008272 R 1134782 CDS YP_006770576.1 410483030 13689396 3009213..3010754 1 NC_018650.1 COG3067 Na+/H+ antiporter; sodium/proton antiporter 3010754 nhaB 13689396 nhaB Escherichia coli O104:H4 str. 2009EL-2050 sodium/proton antiporter YP_006770576.1 3009213 D 1134782 CDS YP_006770577.1 410483031 13689397 3010900..3011430 1 NC_018650.1 COG1495 Disulfide bond formation protein DsbB; disulfide bond formation protein B 3011430 13689397 O3M_14710 Escherichia coli O104:H4 str. 2009EL-2050 disulfide bond formation protein B YP_006770577.1 3010900 D 1134782 CDS YP_006770578.1 410483032 13689398 complement(3011476..3012744) 1 NC_018650.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC 3012744 umuC 13689398 umuC Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase V subunit UmuC YP_006770578.1 3011476 R 1134782 CDS YP_006770579.1 410483033 13689399 complement(3012744..3013163) 1 NC_018650.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); DNA polymerase V subunit UmuD 3013163 13689399 O3M_14720 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase V subunit UmuD YP_006770579.1 3012744 R 1134782 CDS YP_006770580.1 410483034 13689400 3014165..3014446 1 NC_018650.1 hemolysin E 3014446 hlyE 13689400 hlyE Escherichia coli O104:H4 str. 2009EL-2050 hemolysin E YP_006770580.1 3014165 D 1134782 CDS YP_006770581.1 410483035 13689401 complement(3014653..3015099) 1 NC_018650.1 COG2983 Uncharacterized conserved protein; hypothetical protein 3015099 13689401 O3M_14740 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770581.1 3014653 R 1134782 CDS YP_006770582.1 410483036 13689402 complement(3015191..3015850) 1 NC_018650.1 COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); hypothetical protein 3015850 13689402 O3M_14745 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770582.1 3015191 R 1134782 CDS YP_006770583.1 410483037 13689403 complement(3015922..3016248) 1 NC_018650.1 COG3100 Uncharacterized protein conserved in bacteria; hypothetical protein 3016248 13689403 O3M_14750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770583.1 3015922 R 1134782 CDS YP_006770584.1 410483038 13689404 3016457..3016858 1 NC_018650.1 hypothetical protein 3016858 13689404 O3M_14755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770584.1 3016457 D 1134782 CDS YP_006770585.1 410483039 13689405 complement(3016978..3017346) 1 NC_018650.1 hypothetical protein 3017346 13689405 O3M_14760 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770585.1 3016978 R 1134782 CDS YP_006770586.1 410483040 13689406 3017866..3018561 1 NC_018650.1 COG0850 Septum formation inhibitor; septum formation inhibitor 3018561 minC 13689406 minC Escherichia coli O104:H4 str. 2009EL-2050 septum formation inhibitor YP_006770586.1 3017866 D 1134782 CDS YP_006770587.1 410483041 13689407 3018585..3019397 1 NC_018650.1 COG2894 Septum formation inhibitor-activating ATPase; cell division inhibitor MinD 3019397 13689407 O3M_14770 Escherichia coli O104:H4 str. 2009EL-2050 cell division inhibitor MinD YP_006770587.1 3018585 D 1134782 CDS YP_006770588.1 410483042 13689408 3019401..3019667 1 NC_018650.1 COG0851 Septum formation topological specificity factor; cell division topological specificity factor MinE 3019667 minE 13689408 minE Escherichia coli O104:H4 str. 2009EL-2050 cell division topological specificity factor MinE YP_006770588.1 3019401 D 1134782 CDS YP_006770589.1 410483043 13689409 complement(3020039..3020251) 1 NC_018650.1 adhesin 3020251 13689409 O3M_14780 Escherichia coli O104:H4 str. 2009EL-2050 adhesin YP_006770589.1 3020039 R 1134782 CDS YP_006770590.1 410483044 13689410 3021019..3021303 1 NC_018650.1 hypothetical protein 3021303 13689410 O3M_14785 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770590.1 3021019 D 1134782 CDS YP_006770591.1 410483045 13689411 3021313..3021642 1 NC_018650.1 hypothetical protein 3021642 13689411 O3M_14790 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770591.1 3021313 D 1134782 CDS YP_006770592.1 410483046 13689412 complement(3021699..3024020) 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; autotransporter 3024020 13689412 O3M_14795 Escherichia coli O104:H4 str. 2009EL-2050 autotransporter YP_006770592.1 3021699 R 1134782 CDS YP_006770593.1 410483047 13689413 complement(3024137..3024346) 1 NC_018650.1 hypothetical protein 3024346 13689413 O3M_14800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770593.1 3024137 R 1134782 CDS YP_006770594.1 410483048 13689414 complement(3024746..3024964) 1 NC_018650.1 hypothetical protein 3024964 13689414 O3M_14805 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770594.1 3024746 R 1134782 CDS YP_006770595.1 410483049 13689415 complement(3025096..3026619) 1 NC_018650.1 COG2200 FOG: EAL domain; hypothetical protein 3026619 13689415 O3M_14810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770595.1 3025096 R 1134782 CDS YP_006770596.1 410483050 13689416 complement(3026951..3027199) 1 NC_018650.1 hypothetical protein 3027199 13689416 O3M_14815 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770596.1 3026951 R 1134782 CDS YP_006770597.1 410483051 13689417 complement(3027312..3027578) 1 NC_018650.1 hypothetical protein 3027578 13689417 O3M_14820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770597.1 3027312 R 1134782 CDS YP_006770598.1 410483052 13689418 complement(3027607..3027879) 1 NC_018650.1 hypothetical protein 3027879 13689418 O3M_14825 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770598.1 3027607 R 1134782 CDS YP_006770599.1 410483053 13689419 complement(3027922..3028158) 1 NC_018650.1 hypothetical protein 3028158 13689419 O3M_14830 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770599.1 3027922 R 1134782 CDS YP_006770600.1 410483054 13689420 3028473..3029684 1 NC_018650.1 blue-light sensing protein using FAD (BLUF); COG2200 FOG: EAL domain; cyclic-di-GMP phosphodiesterase 3029684 13689420 O3M_14835 Escherichia coli O104:H4 str. 2009EL-2050 cyclic-di-GMP phosphodiesterase YP_006770600.1 3028473 D 1134782 CDS YP_006770601.1 410483055 13689421 3029889..3030620 1 NC_018650.1 COG0789 Predicted transcriptional regulators; DNA-binding transcriptional regulator 3030620 13689421 O3M_14840 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770601.1 3029889 D 1134782 CDS YP_006770602.1 410483056 13689422 3030841..3031245 1 NC_018650.1 COG5562 Phage envelope protein; hypothetical protein 3031245 13689422 O3M_14845 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770602.1 3030841 D 1134782 CDS YP_006770603.1 410483057 13689423 3031941..3032264 1 NC_018650.1 anti-adapter protein IraM 3032264 13689423 O3M_14850 Escherichia coli O104:H4 str. 2009EL-2050 anti-adapter protein IraM YP_006770603.1 3031941 D 1134782 CDS YP_006770604.1 410483058 13689424 complement(3032367..3033617) 1 NC_018650.1 COG0538 Isocitrate dehydrogenases; isocitrate dehydrogenase 3033617 13689424 O3M_14855 Escherichia coli O104:H4 str. 2009EL-2050 isocitrate dehydrogenase YP_006770604.1 3032367 R 1134782 CDS YP_006770605.1 410483059 13689425 3033789..3034442 1 NC_018650.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridine synthase E 3034442 13689425 O3M_14860 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA pseudouridine synthase E YP_006770605.1 3033789 D 1134782 CDS YP_006770606.1 410483060 13689426 3034452..3034913 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase 3034913 13689426 O3M_14865 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase YP_006770606.1 3034452 D 1134782 CDS YP_006770607.1 410483061 13689427 3034967..3036073 1 NC_018650.1 COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; tRNA-specific 2-thiouridylase MnmA 3036073 mnmA 13689427 mnmA Escherichia coli O104:H4 str. 2009EL-2050 tRNA-specific 2-thiouridylase MnmA YP_006770607.1 3034967 D 1134782 CDS YP_006770608.1 410483062 13689428 3036109..3036750 1 NC_018650.1 COG2915 Uncharacterized protein involved in purine metabolism; lysogenization regulator 3036750 13689428 O3M_14875 Escherichia coli O104:H4 str. 2009EL-2050 lysogenization regulator YP_006770608.1 3036109 D 1134782 CDS YP_006770609.1 410483063 13689429 3036754..3038124 1 NC_018650.1 COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 3038124 13689429 O3M_14880 Escherichia coli O104:H4 str. 2009EL-2050 adenylosuccinate lyase YP_006770609.1 3036754 D 1134782 CDS YP_006770610.1 410483064 13689430 3038292..3038963 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator PhoP 3038963 13689430 O3M_14885 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator PhoP YP_006770610.1 3038292 D 1134782 CDS YP_006770611.1 410483065 13689431 3038963..3040423 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor protein PhoQ 3040423 13689431 O3M_14890 Escherichia coli O104:H4 str. 2009EL-2050 sensor protein PhoQ YP_006770611.1 3038963 D 1134782 CDS YP_006770612.1 410483066 13689432 3040499..3041620 1 NC_018650.1 COG2850 Uncharacterized conserved protein; hypothetical protein 3041620 13689432 O3M_14895 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770612.1 3040499 D 1134782 CDS YP_006770613.1 410483067 13689433 complement(3041766..3042995) 1 NC_018650.1 COG2195 Di- and tripeptidases; peptidase T 3042995 13689433 O3M_14900 Escherichia coli O104:H4 str. 2009EL-2050 peptidase T YP_006770613.1 3041766 R 1134782 CDS YP_006770614.1 410483068 13689434 3043245..3044381 1 NC_018650.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; putrescine/spermidine ABC transporter ATPase 3044381 potA 13689434 potA Escherichia coli O104:H4 str. 2009EL-2050 putrescine/spermidine ABC transporter ATPase YP_006770614.1 3043245 D 1134782 CDS YP_006770615.1 410483069 13689435 3044365..3045222 1 NC_018650.1 COG1176 ABC-type spermidine/putrescine transport system, permease component I; spermidine/putrescine ABC transporter permease 3045222 potB 13689435 potB Escherichia coli O104:H4 str. 2009EL-2050 spermidine/putrescine ABC transporter permease YP_006770615.1 3044365 D 1134782 CDS YP_006770616.1 410483070 13689436 3045219..3046013 1 NC_018650.1 COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease 3046013 potC 13689436 potC Escherichia coli O104:H4 str. 2009EL-2050 spermidine/putrescine ABC transporter permease YP_006770616.1 3045219 D 1134782 CDS YP_006770617.1 410483071 13689437 3046010..3047056 1 NC_018650.1 COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine ABC transporter substrate-binding protein 3047056 potD 13689437 potD Escherichia coli O104:H4 str. 2009EL-2050 spermidine/putrescine ABC transporter substrate-binding protein YP_006770617.1 3046010 D 1134782 CDS YP_006770618.1 410483072 13689438 3047114..3047575 1 NC_018650.1 inner membrane protein 3047575 13689438 O3M_14925 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770618.1 3047114 D 1134782 CDS YP_006770619.1 410483073 13689439 3047650..3048360 1 NC_018650.1 inner membrane protein 3048360 13689439 O3M_14930 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770619.1 3047650 D 1134782 CDS YP_006770620.1 410483074 13689440 complement(3048499..3049320) 1 NC_018650.1 COG0846 NAD-dependent protein deacetylases, SIR2 family; NAD-dependent deacetylase 3049320 13689440 O3M_14935 Escherichia coli O104:H4 str. 2009EL-2050 NAD-dependent deacetylase YP_006770620.1 3048499 R 1134782 CDS YP_006770621.1 410483075 13689441 complement(3049336..3050247) 1 NC_018650.1 COG1940 Transcriptional regulator/sugar kinase; N-acetyl-D-glucosamine kinase 3050247 13689441 O3M_14940 Escherichia coli O104:H4 str. 2009EL-2050 N-acetyl-D-glucosamine kinase YP_006770621.1 3049336 R 1134782 CDS YP_006770622.1 410483076 13689442 complement(3050276..3051520) 1 NC_018650.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; outer membrane-specific lipoprotein transporter subunit LolE 3051520 13689442 O3M_14945 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane-specific lipoprotein transporter subunit LolE YP_006770622.1 3050276 R 1134782 CDS YP_006770623.1 410483077 13689443 complement(3051520..3052221) 1 NC_018650.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; lipoprotein transporter ATP-binding subunit 3052221 lolD 13689443 lolD Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein transporter ATP-binding subunit YP_006770623.1 3051520 R 1134782 CDS YP_006770624.1 410483078 13689444 complement(3052214..3053413) 1 NC_018650.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; outer membrane-specific lipoprotein transporter subunit LolC 3053413 13689444 O3M_14955 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane-specific lipoprotein transporter subunit LolC YP_006770624.1 3052214 R 1134782 CDS YP_006770625.1 410483079 13689445 3053675..3054748 1 NC_018650.1 COG4763 Predicted membrane protein; inner membrane protein 3054748 13689445 O3M_14960 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770625.1 3053675 D 1134782 CDS YP_006770626.1 410483080 13689446 3054876..3058322 1 NC_018650.1 COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 3058322 13689446 O3M_14965 Escherichia coli O104:H4 str. 2009EL-2050 transcription-repair coupling factor YP_006770626.1 3054876 D 1134782 CDS YP_006770627.1 410483081 13689447 3058466..3059428 1 NC_018650.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 3059428 13689447 O3M_14970 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770627.1 3058466 D 1134782 CDS YP_006770628.1 410483082 13689448 complement(3059511..3059768) 1 NC_018650.1 hypothetical protein 3059768 13689448 O3M_14975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770628.1 3059511 R 1134782 CDS YP_006770629.1 410483083 13689449 3060009..3060641 1 NC_018650.1 COG1309 Transcriptional regulator; hypothetical protein 3060641 13689449 O3M_14980 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770629.1 3060009 D 1134782 CDS YP_006770630.1 410483084 13689450 complement(3060703..3061242) 1 NC_018650.1 COG3134 Predicted outer membrane lipoprotein; hypothetical protein 3061242 13689450 O3M_14985 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770630.1 3060703 R 1134782 CDS YP_006770631.1 410483085 13689451 complement(3061452..3062756) 1 NC_018650.1 COG1252 NADH dehydrogenase, FAD-containing subunit; respiratory NADH dehydrogenase 2/cupric reductase 3062756 13689451 O3M_14990 Escherichia coli O104:H4 str. 2009EL-2050 respiratory NADH dehydrogenase 2/cupric reductase YP_006770631.1 3061452 R 1134782 CDS YP_006770632.1 410483086 13689452 complement(3063164..3063706) 1 NC_018650.1 COG3150 Predicted esterase; hypothetical protein 3063706 13689452 O3M_14995 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770632.1 3063164 R 1134782 CDS YP_006770633.1 410483087 13689453 complement(3063729..3064754) 1 NC_018650.1 COG1472 Beta-glucosidase-related glycosidases; beta-hexosaminidase 3064754 13689453 O3M_15000 Escherichia coli O104:H4 str. 2009EL-2050 beta-hexosaminidase YP_006770633.1 3063729 R 1134782 CDS YP_006770634.1 410483088 13689454 complement(3064765..3065589) 1 NC_018650.1 COG0510 Predicted choline kinase involved in LPS biosynthesis; thiamine kinase 3065589 thiK 13689454 thiK Escherichia coli O104:H4 str. 2009EL-2050 thiamine kinase YP_006770634.1 3064765 R 1134782 CDS YP_006770635.1 410483089 13689455 complement(3065570..3066211) 1 NC_018650.1 COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family); hypothetical protein 3066211 13689455 O3M_15010 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770635.1 3065570 R 1134782 CDS YP_006770636.1 410483090 13689456 complement(3066225..3066602) 1 NC_018650.1 COG5633 Predicted periplasmic lipoprotein; lipoprotein 3066602 13689456 O3M_15015 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770636.1 3066225 R 1134782 CDS YP_006770637.1 410483091 13689457 complement(3066605..3066964) 1 NC_018650.1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; purine nucleoside phosphoramidase 3066964 13689457 O3M_15020 Escherichia coli O104:H4 str. 2009EL-2050 purine nucleoside phosphoramidase YP_006770637.1 3066605 R 1134782 CDS YP_006770638.1 410483092 13689458 3067298..3069487 1 NC_018650.1 COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid; ferric-rhodotorulic acid outer membrane transporter 3069487 13689458 O3M_15025 Escherichia coli O104:H4 str. 2009EL-2050 ferric-rhodotorulic acid outer membrane transporter YP_006770638.1 3067298 D 1134782 CDS YP_006770639.1 410483093 13689459 complement(3069547..3070980) 1 NC_018650.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose-specific transporter subunit IIBC 3070980 13689459 O3M_15030 Escherichia coli O104:H4 str. 2009EL-2050 PTS system glucose-specific transporter subunit IIBC YP_006770639.1 3069547 R 1134782 CDS YP_006770640.1 410483094 13689460 complement(3071275..3072072) 1 NC_018650.1 COG0084 Mg-dependent DNase; DNAse 3072072 13689460 O3M_15035 Escherichia coli O104:H4 str. 2009EL-2050 DNAse YP_006770640.1 3071275 R 1134782 CDS YP_006770641.1 410483095 13689461 complement(3072083..3073087) 1 NC_018650.1 COG0470 ATPase involved in DNA replication; DNA polymerase III subunit delta' 3073087 13689461 O3M_15040 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit delta' YP_006770641.1 3072083 R 1134782 CDS YP_006770642.1 410483096 13689462 complement(3073084..3073725) 1 NC_018650.1 COG0125 Thymidylate kinase; thymidylate kinase 3073725 tmk 13689462 tmk Escherichia coli O104:H4 str. 2009EL-2050 thymidylate kinase YP_006770642.1 3073084 R 1134782 CDS YP_006770643.1 410483097 13689463 complement(3073715..3074737) 1 NC_018650.1 COG1559 Predicted periplasmic solute-binding protein; aminodeoxychorismate lyase 3074737 13689463 O3M_15050 Escherichia coli O104:H4 str. 2009EL-2050 aminodeoxychorismate lyase YP_006770643.1 3073715 R 1134782 CDS YP_006770644.1 410483098 13689464 complement(3074740..3075549) 1 NC_018650.1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; 4-amino-4-deoxychorismate lyase 3075549 13689464 O3M_15055 Escherichia coli O104:H4 str. 2009EL-2050 4-amino-4-deoxychorismate lyase YP_006770644.1 3074740 R 1134782 CDS YP_006770645.1 410483099 13689465 complement(3075669..3076910) 1 NC_018650.1 COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-(acyl carrier protein) synthase II 3076910 13689465 O3M_15060 Escherichia coli O104:H4 str. 2009EL-2050 3-oxoacyl-(acyl carrier protein) synthase II YP_006770645.1 3075669 R 1134782 CDS YP_006770646.1 410483100 13689466 complement(3076998..3077234) 1 NC_018650.1 COG0236 Acyl carrier protein; hypothetical protein 3077234 13689466 O3M_15065 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770646.1 3076998 R 1134782 CDS YP_006770647.1 410483101 13689467 complement(3077445..3078179) 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-ACP reductase 3078179 fabG 13689467 fabG Escherichia coli O104:H4 str. 2009EL-2050 3-ketoacyl-ACP reductase YP_006770647.1 3077445 R 1134782 CDS YP_006770648.1 410483102 13689468 complement(3078192..3079121) 1 NC_018650.1 COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl-CoA-[acyl-carrier-protein] transacylase 3079121 13689468 O3M_15075 Escherichia coli O104:H4 str. 2009EL-2050 malonyl-CoA-[acyl-carrier-protein] transacylase YP_006770648.1 3078192 R 1134782 CDS YP_006770649.1 410483103 13689469 complement(3079137..3080090) 1 NC_018650.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-ACP synthase 3080090 13689469 O3M_15080 Escherichia coli O104:H4 str. 2009EL-2050 3-oxoacyl-ACP synthase YP_006770649.1 3079137 R 1134782 CDS YP_006770650.1 410483104 13689470 complement(3080158..3081228) 1 NC_018650.1 COG0416 Fatty acid/phospholipid biosynthesis enzyme; phosphate acyltransferase 3081228 13689470 O3M_15085 Escherichia coli O104:H4 str. 2009EL-2050 phosphate acyltransferase YP_006770650.1 3080158 R 1134782 CDS YP_006770651.1 410483105 13689471 complement(3081309..3081482) 1 NC_018650.1 COG0333 Ribosomal protein L32; 50S ribosomal protein L32 3081482 rpmF 13689471 rpmF Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L32 YP_006770651.1 3081309 R 1134782 CDS YP_006770652.1 410483106 13689472 complement(3081534..3082055) 1 NC_018650.1 COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; hypothetical protein 3082055 13689472 O3M_15095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770652.1 3081534 R 1134782 CDS YP_006770653.1 410483107 13689473 3082254..3082838 1 NC_018650.1 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; maf-like protein 3082838 13689473 O3M_15100 Escherichia coli O104:H4 str. 2009EL-2050 maf-like protein YP_006770653.1 3082254 D 1134782 CDS YP_006770654.1 410483108 13689474 complement(3082950..3083909) 1 NC_018650.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA pseudouridylate synthase C 3083909 13689474 O3M_15105 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA pseudouridylate synthase C YP_006770654.1 3082950 R 1134782 CDS YP_006770655.1 410483109 13689475 complement(3084027..3084401) 1 NC_018650.1 hypothetical protein 3084401 13689475 O3M_15110 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770655.1 3084027 R 1134782 CDS YP_006770656.1 410483110 13689476 3084482..3087667 1 NC_018650.1 COG1530 Ribonucleases G and E; ribonuclease E 3087667 rne 13689476 rne Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease E YP_006770656.1 3084482 D 1134782 CDS YP_006770657.1 410483111 13689477 complement(3087864..3088817) 1 NC_018650.1 COG1344 Flagellin and related hook-associated proteins; flagellar hook-associated protein FlgL 3088817 flgL 13689477 flgL Escherichia coli O104:H4 str. 2009EL-2050 flagellar hook-associated protein FlgL YP_006770657.1 3087864 R 1134782 CDS YP_006770658.1 410483112 13689478 complement(3088829..3090472) 1 NC_018650.1 COG1256 Flagellar hook-associated protein; flagellar hook-associated protein FlgK 3090472 flgK 13689478 flgK Escherichia coli O104:H4 str. 2009EL-2050 flagellar hook-associated protein FlgK YP_006770658.1 3088829 R 1134782 CDS YP_006770659.1 410483113 13689479 complement(3090538..3091479) 1 NC_018650.1 COG3951 Rod binding protein; flagellar rod assembly protein/muramidase FlgJ 3091479 flgJ 13689479 flgJ Escherichia coli O104:H4 str. 2009EL-2050 flagellar rod assembly protein/muramidase FlgJ YP_006770659.1 3090538 R 1134782 CDS YP_006770660.1 410483114 13689480 complement(3091479..3092576) 1 NC_018650.1 COG1706 Flagellar basal-body P-ring protein; flagellar basal body P-ring protein 3092576 flgI 13689480 flgI Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body P-ring protein YP_006770660.1 3091479 R 1134782 CDS YP_006770661.1 410483115 13689481 complement(3092588..3093286) 1 NC_018650.1 COG2063 Flagellar basal body L-ring protein; flagellar basal body L-ring protein 3093286 flgH 13689481 flgH Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body L-ring protein YP_006770661.1 3092588 R 1134782 CDS YP_006770662.1 410483116 13689482 complement(3093339..3094121) 1 NC_018650.1 COG4786 Flagellar basal body rod protein; flagellar basal body rod protein FlgG 3094121 flgG 13689482 flgG Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body rod protein FlgG YP_006770662.1 3093339 R 1134782 CDS YP_006770663.1 410483117 13689483 complement(3094293..3095048) 1 NC_018650.1 COG4787 Flagellar basal body rod protein; flagellar basal body rod protein FlgF 3095048 flgF 13689483 flgF Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body rod protein FlgF YP_006770663.1 3094293 R 1134782 CDS YP_006770664.1 410483118 13689484 complement(3095068..3096273) 1 NC_018650.1 COG1749 Flagellar hook protein FlgE; flagellar hook protein FlgE 3096273 flgE 13689484 flgE Escherichia coli O104:H4 str. 2009EL-2050 flagellar hook protein FlgE YP_006770664.1 3095068 R 1134782 CDS YP_006770665.1 410483119 13689485 complement(3096298..3096993) 1 NC_018650.1 COG1843 Flagellar hook capping protein; flagellar basal body rod modification protein 3096993 flgD 13689485 flgD Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body rod modification protein YP_006770665.1 3096298 R 1134782 CDS YP_006770666.1 410483120 13689486 complement(3097005..3097409) 1 NC_018650.1 COG1558 Flagellar basal body rod protein; flagellar basal body rod protein FlgC 3097409 flgC 13689486 flgC Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body rod protein FlgC YP_006770666.1 3097005 R 1134782 CDS YP_006770667.1 410483121 13689487 complement(3097413..3097829) 1 NC_018650.1 COG1815 Flagellar basal body protein; flagellar basal body rod protein FlgB 3097829 flgB 13689487 flgB Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body rod protein FlgB YP_006770667.1 3097413 R 1134782 CDS YP_006770668.1 410483122 13689488 3097984..3098643 1 NC_018650.1 COG1261 Flagellar basal body P-ring biosynthesis protein; flagellar basal body P-ring biosynthesis protein FlgA 3098643 flgA 13689488 flgA Escherichia coli O104:H4 str. 2009EL-2050 flagellar basal body P-ring biosynthesis protein FlgA YP_006770668.1 3097984 D 1134782 CDS YP_006770669.1 410483123 13689489 3098719..3099012 1 NC_018650.1 COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor); anti-sigma-28 factor FlgM 3099012 13689489 O3M_15180 Escherichia coli O104:H4 str. 2009EL-2050 anti-sigma-28 factor FlgM YP_006770669.1 3098719 D 1134782 CDS YP_006770670.1 410483124 13689490 3099017..3099433 1 NC_018650.1 COG3418 Flagellar biosynthesis/type III secretory pathway chaperone; flagella synthesis chaperone protein FlgN 3099433 13689490 O3M_15185 Escherichia coli O104:H4 str. 2009EL-2050 flagella synthesis chaperone protein FlgN YP_006770670.1 3099017 D 1134782 CDS YP_006770671.1 410483125 13689491 complement(3099473..3101008) 1 NC_018650.1 COG0728 Uncharacterized membrane protein, putative virulence factor; inner membrane protein MviN 3101008 13689491 O3M_15190 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein MviN YP_006770671.1 3099473 R 1134782 CDS YP_006770672.1 410483126 13689492 complement(3101118..3102041) 1 NC_018650.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 3102041 13689492 O3M_15195 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006770672.1 3101118 R 1134782 CDS YP_006770673.1 410483127 13689493 complement(3102043..3102690) 1 NC_018650.1 COG3132 Uncharacterized protein conserved in bacteria; hypothetical protein 3102690 13689493 O3M_15200 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770673.1 3102043 R 1134782 CDS YP_006770674.1 410483128 13689494 complement(3102701..3103285) 1 NC_018650.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-S5-alanine N-acetyltransferase 3103285 13689494 O3M_15205 Escherichia coli O104:H4 str. 2009EL-2050 ribosomal-protein-S5-alanine N-acetyltransferase YP_006770674.1 3102701 R 1134782 CDS YP_006770675.1 410483129 13689495 3103521..3104729 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein MdtH 3104729 13689495 O3M_15210 Escherichia coli O104:H4 str. 2009EL-2050 multidrug resistance protein MdtH YP_006770675.1 3103521 D 1134782 CDS YP_006770676.1 410483130 13689496 3104793..3105440 1 NC_018650.1 COG2999 Glutaredoxin 2; glutaredoxin 3105440 13689496 O3M_15215 Escherichia coli O104:H4 str. 2009EL-2050 glutaredoxin YP_006770676.1 3104793 D 1134782 CDS YP_006770677.1 410483131 13689497 3105574..3106134 1 NC_018650.1 lipoprotein 3106134 13689497 O3M_15220 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770677.1 3105574 D 1134782 CDS YP_006770678.1 410483132 13689498 3106240..3107286 1 NC_018650.1 COG0418 Dihydroorotase; dihydroorotase 3107286 13689498 O3M_15225 Escherichia coli O104:H4 str. 2009EL-2050 dihydroorotase YP_006770678.1 3106240 D 1134782 CDS YP_006770679.1 410483133 13689499 3107360..3107605 1 NC_018650.1 DNA damage-inducible protein I 3107605 13689499 O3M_15230 Escherichia coli O104:H4 str. 2009EL-2050 DNA damage-inducible protein I YP_006770679.1 3107360 D 1134782 CDS YP_006770680.1 410483134 13689500 3107895..3108149 1 NC_018650.1 biofilm formation regulatory protein BssS 3108149 bssS 13689500 bssS Escherichia coli O104:H4 str. 2009EL-2050 biofilm formation regulatory protein BssS YP_006770680.1 3107895 D 1134782 CDS YP_006770681.1 410483135 13689501 3108264..3109382 1 NC_018650.1 COG0665 Glycine/D-amino acid oxidases (deaminating); N-methyltryptophan oxidase 3109382 solA 13689501 solA Escherichia coli O104:H4 str. 2009EL-2050 N-methyltryptophan oxidase YP_006770681.1 3108264 D 1134782 CDS YP_006770682.1 410483136 13689502 3109430..3109543 1 NC_018650.1 hypothetical protein 3109543 13689502 O3M_15245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770682.1 3109430 D 1134782 CDS YP_006770683.1 410483137 13689503 3109804..3110370 1 NC_018650.1 COG3038 Cytochrome B561; cytochrome 3110370 13689503 O3M_15250 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome YP_006770683.1 3109804 D 1134782 CDS YP_006770684.1 410483138 13689504 3110374..3110949 1 NC_018650.1 COG2353 Uncharacterized conserved protein; hypothetical protein 3110949 13689504 O3M_15255 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770684.1 3110374 D 1134782 CDS YP_006770685.1 410483139 13689505 complement(3110991..3112043) 1 NC_018650.1 COG1054 Predicted sulfurtransferase; rhodanese-related sulfurtransferase 3112043 13689505 O3M_15260 Escherichia coli O104:H4 str. 2009EL-2050 rhodanese-related sulfurtransferase YP_006770685.1 3110991 R 1134782 CDS YP_006770686.1 410483140 13689506 3112268..3113188 1 NC_018650.1 COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis lauroyl acyltransferase 3113188 13689506 O3M_15265 Escherichia coli O104:H4 str. 2009EL-2050 lipid A biosynthesis lauroyl acyltransferase YP_006770686.1 3112268 D 1134782 CDS YP_006770687.1 410483141 13689507 3113360..3114586 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; drug efflux system protein MdtG 3114586 13689507 O3M_15270 Escherichia coli O104:H4 str. 2009EL-2050 drug efflux system protein MdtG YP_006770687.1 3113360 D 1134782 CDS YP_006770688.1 410483142 13689508 3114669..3115043 1 NC_018650.1 secY/secA suppressor protein 3115043 13689508 O3M_15275 Escherichia coli O104:H4 str. 2009EL-2050 secY/secA suppressor protein YP_006770688.1 3114669 D 1134782 CDS YP_006770689.1 410483143 13689509 complement(3115044..3115271) 1 NC_018650.1 COG5645 Predicted periplasmic lipoprotein; lipoprotein 3115271 13689509 O3M_15280 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770689.1 3115044 R 1134782 CDS YP_006770690.1 410483144 13689510 complement(3115444..3117987) 1 NC_018650.1 COG2943 Membrane glycosyltransferase; glucosyltransferase MdoH 3117987 13689510 O3M_15285 Escherichia coli O104:H4 str. 2009EL-2050 glucosyltransferase MdoH YP_006770690.1 3115444 R 1134782 CDS YP_006770691.1 410483145 13689511 complement(3117980..3119515) 1 NC_018650.1 COG3131 Periplasmic glucans biosynthesis protein; glucan biosynthesis protein G 3119515 mdoG 13689511 mdoG Escherichia coli O104:H4 str. 2009EL-2050 glucan biosynthesis protein G YP_006770691.1 3117980 R 1134782 CDS YP_006770692.1 410483146 13689512 3119909..3121066 1 NC_018650.1 glucans biosynthesis protein 3121066 opgC 13689512 opgC Escherichia coli O104:H4 str. 2009EL-2050 glucans biosynthesis protein YP_006770692.1 3119909 D 1134782 CDS YP_006770693.1 410483147 13689513 complement(3121074..3122495) 1 NC_018650.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phospholipase D/transphosphatidylase 3122495 13689513 O3M_15300 Escherichia coli O104:H4 str. 2009EL-2050 phospholipase D/transphosphatidylase YP_006770693.1 3121074 R 1134782 CDS YP_006770694.1 410483148 13689514 complement(3122497..3123030) 1 NC_018650.1 COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; RNase III inhibitor 3123030 13689514 O3M_15305 Escherichia coli O104:H4 str. 2009EL-2050 RNase III inhibitor YP_006770694.1 3122497 R 1134782 CDS YP_006770695.1 410483149 13689515 complement(3123125..3123325) 1 NC_018650.1 hypothetical protein 3123325 13689515 O3M_15310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770695.1 3123125 R 1134782 CDS YP_006770696.1 410483150 13689516 complement(3123556..3123888) 1 NC_018650.1 curli assembly protein CsgC 3123888 csgC 13689516 csgC Escherichia coli O104:H4 str. 2009EL-2050 curli assembly protein CsgC YP_006770696.1 3123556 R 1134782 CDS YP_006770697.1 410483151 13689517 complement(3123947..3124402) 1 NC_018650.1 major curlin subunit 3124402 csgA 13689517 csgA Escherichia coli O104:H4 str. 2009EL-2050 major curlin subunit YP_006770697.1 3123947 R 1134782 CDS YP_006770698.1 410483152 13689518 complement(3124443..3124898) 1 NC_018650.1 curlin minor subunit CsgB 3124898 csgB 13689518 csgB Escherichia coli O104:H4 str. 2009EL-2050 curlin minor subunit CsgB YP_006770698.1 3124443 R 1134782 CDS YP_006770699.1 410483153 13689519 3125652..3126302 1 NC_018650.1 COG2771 DNA-binding HTH domain-containing proteins; DNA-binding transcriptional regulator CsgD 3126302 13689519 O3M_15330 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator CsgD YP_006770699.1 3125652 D 1134782 CDS YP_006770700.1 410483154 13689520 3126307..3126696 1 NC_018650.1 COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; curli assembly protein CsgE 3126696 13689520 O3M_15335 Escherichia coli O104:H4 str. 2009EL-2050 curli assembly protein CsgE YP_006770700.1 3126307 D 1134782 CDS YP_006770701.1 410483155 13689521 3126721..3127137 1 NC_018650.1 curli assembly protein CsgF 3127137 13689521 O3M_15340 Escherichia coli O104:H4 str. 2009EL-2050 curli assembly protein CsgF YP_006770701.1 3126721 D 1134782 CDS YP_006770702.1 410483156 13689522 3127164..3127997 1 NC_018650.1 COG1462 Uncharacterized protein involved in formation of curli polymers; curli production assembly/transport protein CsgG 3127997 13689522 O3M_15345 Escherichia coli O104:H4 str. 2009EL-2050 curli production assembly/transport protein CsgG YP_006770702.1 3127164 D 1134782 CDS YP_006770703.1 410483157 13689523 complement(3128061..3128552) 1 NC_018650.1 inner membrane protein 3128552 13689523 O3M_15350 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770703.1 3128061 R 1134782 CDS YP_006770704.1 410483158 13689524 complement(3128654..3129208) 1 NC_018650.1 COG3381 Uncharacterized component of anaerobic dehydrogenases; hypothetical protein 3129208 13689524 O3M_15355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770704.1 3128654 R 1134782 CDS YP_006770705.1 410483159 13689525 complement(3129232..3129969) 1 NC_018650.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; hydrolase 3129969 13689525 O3M_15360 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006770705.1 3129232 R 1134782 CDS YP_006770706.1 410483160 13689526 complement(3130024..3130962) 1 NC_018650.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; bifunctional glyoxylate/hydroxypyruvate reductase A 3130962 ghrA 13689526 ghrA Escherichia coli O104:H4 str. 2009EL-2050 bifunctional glyoxylate/hydroxypyruvate reductase A YP_006770706.1 3130024 R 1134782 CDS YP_006770707.1 410483161 13689528 complement(3131433..3132275) 1 NC_018650.1 hypothetical protein 3132275 13689528 O3M_15370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770707.1 3131433 R 1134782 CDS YP_006770708.1 410483162 13689529 complement(3132360..3132557) 1 NC_018650.1 hypothetical protein 3132557 13689529 O3M_15375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770708.1 3132360 R 1134782 CDS YP_006770709.1 410483163 13689530 complement(3132569..3133057) 1 NC_018650.1 hypothetical protein 3133057 13689530 O3M_15380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770709.1 3132569 R 1134782 CDS YP_006770710.1 410483164 13689531 complement(3133057..3133431) 1 NC_018650.1 hypothetical protein 3133431 13689531 O3M_15385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770710.1 3133057 R 1134782 CDS YP_006770711.1 410483165 13689532 complement(3133522..3133875) 1 NC_018650.1 CP4-44 prophage YeeV-YeeU toxin-antitoxin system toxin 3133875 13689532 O3M_15390 Escherichia coli O104:H4 str. 2009EL-2050 CP4-44 prophage YeeV-YeeU toxin-antitoxin system toxin YP_006770711.1 3133522 R 1134782 CDS YP_006770712.1 410483166 13689533 complement(3133951..3134172) 1 NC_018650.1 hypothetical protein 3134172 13689533 O3M_15395 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770712.1 3133951 R 1134782 CDS YP_006770713.1 410483167 13689534 complement(3134235..3134711) 1 NC_018650.1 COG2003 DNA repair proteins; radC-like protein YeeS 3134711 13689534 O3M_15400 Escherichia coli O104:H4 str. 2009EL-2050 radC-like protein YeeS YP_006770713.1 3134235 R 1134782 CDS YP_006770714.1 410483168 13689535 complement(3134727..3135200) 1 NC_018650.1 hypothetical protein 3135200 13689535 O3M_15405 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770714.1 3134727 R 1134782 CDS YP_006770715.1 410483169 13689536 complement(3135294..3135539) 1 NC_018650.1 hypothetical protein 3135539 13689536 O3M_15410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770715.1 3135294 R 1134782 CDS YP_006770716.1 410483170 13689537 complement(3135539..3136360) 1 NC_018650.1 hypothetical protein 3136360 13689537 O3M_15415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770716.1 3135539 R 1134782 CDS YP_006770717.1 410483171 13689538 complement(3136608..3138221) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; transposase 3138221 13689538 O3M_15420 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006770717.1 3136608 R 1134782 CDS YP_006770718.1 410483172 13689539 complement(3138252..3138602) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 3138602 13689539 O3M_15425 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770718.1 3138252 R 1134782 CDS YP_006770719.1 410483173 13689540 complement(3138599..3139033) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 3139033 13689540 O3M_15430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770719.1 3138599 R 1134782 CDS YP_006770720.1 410483174 13689541 complement(3139130..3139540) 1 NC_018650.1 hypothetical protein 3139540 13689541 O3M_15435 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770720.1 3139130 R 1134782 CDS YP_006770721.1 410483175 13689542 complement(3139556..3140239) 1 NC_018650.1 hypothetical protein 3140239 13689542 O3M_15440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770721.1 3139556 R 1134782 CDS YP_006770722.1 410483176 13689543 complement(3140373..3141443) 1 NC_018650.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein 3141443 13689543 O3M_15445 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770722.1 3140373 R 1134782 CDS YP_006770723.1 410483177 13689544 complement(3141440..3142345) 1 NC_018650.1 hypothetical protein 3142345 13689544 O3M_15450 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770723.1 3141440 R 1134782 CDS YP_006770724.1 410483178 13689545 complement(3142342..3144738) 1 NC_018650.1 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 3144738 13689545 O3M_15455 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770724.1 3142342 R 1134782 CDS YP_006770725.1 410483179 13689546 complement(3147210..3148082) 1 NC_018650.1 COG3596 Predicted GTPase; GTP-binding protein 3148082 13689546 O3M_15475 Escherichia coli O104:H4 str. 2009EL-2050 GTP-binding protein YP_006770725.1 3147210 R 1134782 CDS YP_006770726.1 410483180 13689547 complement(3148894..3149319) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS66 transposase 3149319 13689547 O3M_15480 Escherichia coli O104:H4 str. 2009EL-2050 IS66 transposase YP_006770726.1 3148894 R 1134782 CDS YP_006770727.1 410483181 13689548 complement(3149477..3150718) 1 NC_018650.1 COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein TerF 3150718 13689548 O3M_15485 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein TerF YP_006770727.1 3149477 R 1134782 CDS YP_006770728.1 410483182 13689549 complement(3151150..3151725) 1 NC_018650.1 COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein TerE 3151725 13689549 O3M_15490 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein TerE YP_006770728.1 3151150 R 1134782 CDS YP_006770729.1 410483183 13689550 complement(3151794..3152372) 1 NC_018650.1 COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein 3152372 13689550 O3M_15495 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein YP_006770729.1 3151794 R 1134782 CDS YP_006770730.1 410483184 13689551 complement(3152421..3153461) 1 NC_018650.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; Tellurium resistance protein TerC 3153461 13689551 O3M_15500 Escherichia coli O104:H4 str. 2009EL-2050 Tellurium resistance protein TerC YP_006770730.1 3152421 R 1134782 CDS YP_006770731.1 410483185 13689552 complement(3153484..3153939) 1 NC_018650.1 COG3793 Tellurite resistance protein; tellurium resistance protein TerB 3153939 13689552 O3M_15505 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein TerB YP_006770731.1 3153484 R 1134782 CDS YP_006770732.1 410483186 13689553 complement(3153962..3155119) 1 NC_018650.1 COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein TerA 3155119 13689553 O3M_15510 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein TerA YP_006770732.1 3153962 R 1134782 CDS YP_006770733.1 410483187 13689554 complement(3155119..3155700) 1 NC_018650.1 COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein 3155700 13689554 O3M_15515 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein YP_006770733.1 3155119 R 1134782 CDS YP_006770734.1 410483188 13689555 3156023..3157081 1 NC_018650.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein 3157081 13689555 O3M_15520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770734.1 3156023 D 1134782 CDS YP_006770735.1 410483189 13689556 3157091..3158233 1 NC_018650.1 hypothetical protein 3158233 13689556 O3M_15525 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770735.1 3157091 D 1134782 CDS YP_006770736.1 410483190 13689557 3158226..3158999 1 NC_018650.1 COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 3158999 13689557 O3M_15530 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770736.1 3158226 D 1134782 CDS YP_006770737.1 410483191 13689558 3159001..3160080 1 NC_018650.1 ATP-binding protein 3160080 13689558 O3M_15535 Escherichia coli O104:H4 str. 2009EL-2050 ATP-binding protein YP_006770737.1 3159001 D 1134782 CDS YP_006770738.1 410483192 13689559 3160080..3161036 1 NC_018650.1 COG2301 Citrate lyase beta subunit; hypothetical protein 3161036 13689559 O3M_15540 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770738.1 3160080 D 1134782 CDS YP_006770739.1 410483193 13689560 3161047..3162255 1 NC_018650.1 hypothetical protein 3162255 13689560 O3M_15545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770739.1 3161047 D 1134782 CDS YP_006770740.1 410483194 13689561 3162273..3162740 1 NC_018650.1 tellurium resistance protein TerW 3162740 13689561 O3M_15550 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein TerW YP_006770740.1 3162273 D 1134782 CDS YP_006770741.1 410483195 13689562 3163204..3163842 1 NC_018650.1 COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY1 3163842 13689562 O3M_15555 Escherichia coli O104:H4 str. 2009EL-2050 TerY1 YP_006770741.1 3163204 D 1134782 CDS YP_006770742.1 410483196 13689563 3163865..3164503 1 NC_018650.1 COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; tellurium resistance protein terX 3164503 13689563 O3M_15560 Escherichia coli O104:H4 str. 2009EL-2050 tellurium resistance protein terX YP_006770742.1 3163865 D 1134782 CDS YP_006770743.1 410483197 13689564 3164503..3165141 1 NC_018650.1 COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY2 3165141 13689564 O3M_15565 Escherichia coli O104:H4 str. 2009EL-2050 TerY2 YP_006770743.1 3164503 D 1134782 CDS YP_006770744.1 410483198 13689565 3165226..3166266 1 NC_018650.1 COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; TerY3 3166266 13689565 O3M_15570 Escherichia coli O104:H4 str. 2009EL-2050 TerY3 YP_006770744.1 3165226 D 1134782 CDS YP_006770745.1 410483199 13689566 3166266..3167903 1 NC_018650.1 hypothetical protein 3167903 13689566 O3M_15575 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770745.1 3166266 D 1134782 CDS YP_006770746.1 410483200 13689567 3167929..3169428 1 NC_018650.1 COG0515 Serine/threonine protein kinase; protein kinase 3169428 13689567 O3M_15580 Escherichia coli O104:H4 str. 2009EL-2050 protein kinase YP_006770746.1 3167929 D 1134782 CDS YP_006770747.1 410483201 13689568 3169516..3170184 1 NC_018650.1 COG4584 Transposase and inactivated derivatives; transposase 3170184 13689568 O3M_15585 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006770747.1 3169516 D 1134782 CDS YP_006770748.1 410483202 13689569 3170259..3170444 1 NC_018650.1 COG1484 DNA replication protein; IS100 transposase 3170444 13689569 O3M_15590 Escherichia coli O104:H4 str. 2009EL-2050 IS100 transposase YP_006770748.1 3170259 D 1134782 CDS YP_006770749.1 410483203 13689571 3171013..3171189 1 NC_018650.1 hypothetical protein 3171189 13689571 O3M_15595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770749.1 3171013 D 1134782 CDS YP_006770750.1 410483204 13689572 3171809..3172054 1 NC_018650.1 COG1943 Transposase and inactivated derivatives; transposase IS605 family, IS200 group 3172054 13689572 O3M_15600 Escherichia coli O104:H4 str. 2009EL-2050 transposase IS605 family, IS200 group YP_006770750.1 3171809 D 1134782 CDS YP_006770751.1 410483205 13689573 complement(3172172..3173110) 1 NC_018650.1 COG0583 Transcriptional regulator; cell density-dependent motility repressor 3173110 13689573 O3M_15605 Escherichia coli O104:H4 str. 2009EL-2050 cell density-dependent motility repressor YP_006770751.1 3172172 R 1134782 CDS YP_006770752.1 410483206 13689574 3173461..3174180 1 NC_018650.1 COG1794 Aspartate racemase; aspartate racemase 3174180 13689574 O3M_15610 Escherichia coli O104:H4 str. 2009EL-2050 aspartate racemase YP_006770752.1 3173461 D 1134782 CDS YP_006770753.1 410483207 13689575 3174246..3175544 1 NC_018650.1 COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 3175544 13689575 O3M_15615 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic C4-dicarboxylate transporter YP_006770753.1 3174246 D 1134782 CDS YP_006770754.1 410483208 13689576 complement(3175788..3176501) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; IS600 orfB 3176501 13689576 O3M_15620 Escherichia coli O104:H4 str. 2009EL-2050 IS600 orfB YP_006770754.1 3175788 R 1134782 CDS YP_006770755.1 410483209 13689577 complement(3176586..3176795) 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; insertion element protein 3176795 13689577 O3M_15625 Escherichia coli O104:H4 str. 2009EL-2050 insertion element protein YP_006770755.1 3176586 R 1134782 CDS YP_006770756.1 410483210 13689578 complement(3176796..3177089) 1 NC_018650.1 IS1; transposase ORF B, IS1 3177089 13689578 O3M_15630 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF B, IS1 YP_006770756.1 3176796 R 1134782 CDS YP_006770757.1 410483211 13689579 complement(3177008..3177283) 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA 3177283 13689579 O3M_15635 Escherichia coli O104:H4 str. 2009EL-2050 IS1 repressor protein InsA YP_006770757.1 3177008 R 1134782 CDS YP_006770758.1 410483212 13689580 complement(3177312..3177431) 1 NC_018650.1 hypothetical protein 3177431 13689580 O3M_15640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770758.1 3177312 R 1134782 CDS YP_006770759.1 410483213 13689581 complement(3177551..3178648) 1 NC_018650.1 COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase; hypothetical protein 3178648 13689581 O3M_15645 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770759.1 3177551 R 1134782 CDS YP_006770760.1 410483214 13689582 complement(3179157..3181376) 1 NC_018650.1 COG1112 Superfamily I DNA and RNA helicases and helicase subunits; UvrD/REP helicase-like protein 3181376 13689582 O3M_15650 Escherichia coli O104:H4 str. 2009EL-2050 UvrD/REP helicase-like protein YP_006770760.1 3179157 R 1134782 CDS YP_006770761.1 410483215 13689583 complement(3182080..3182655) 1 NC_018650.1 hypothetical protein 3182655 13689583 O3M_15655 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770761.1 3182080 R 1134782 CDS YP_006770762.1 410483216 13689584 complement(3183401..3183619) 1 NC_018650.1 hypothetical protein 3183619 13689584 O3M_15660 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770762.1 3183401 R 1134782 CDS YP_006770763.1 410483217 13689585 complement(3183630..3183863) 1 NC_018650.1 hypothetical protein 3183863 13689585 O3M_15665 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770763.1 3183630 R 1134782 CDS YP_006770764.1 410483218 13689586 complement(3183959..3184582) 1 NC_018650.1 hypothetical protein 3184582 13689586 O3M_15670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770764.1 3183959 R 1134782 CDS YP_006770765.1 410483219 13689587 3186525..3186881 1 NC_018650.1 COG1266 Predicted metal-dependent membrane protease; hypothetical protein 3186881 13689587 O3M_15675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770765.1 3186525 D 1134782 CDS YP_006770766.1 410483220 13689588 complement(3187877..3189979) 1 NC_018650.1 COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; colicin V secretion/processing ATP binding protein 3189979 13689588 O3M_15680 Escherichia coli O104:H4 str. 2009EL-2050 colicin V secretion/processing ATP binding protein YP_006770766.1 3187877 R 1134782 CDS YP_006770767.1 410483221 13689589 complement(3189972..3191159) 1 NC_018650.1 COG0845 Membrane-fusion protein; Colicin V secretion protein CvaA 3191159 13689589 O3M_15685 Escherichia coli O104:H4 str. 2009EL-2050 Colicin V secretion protein CvaA YP_006770767.1 3189972 R 1134782 CDS YP_006770768.1 410483222 13689590 complement(3191399..3191851) 1 NC_018650.1 COG2994 ACP:hemolysin acyltransferase (hemolysin-activating protein); hypothetical protein 3191851 13689590 O3M_15690 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770768.1 3191399 R 1134782 CDS YP_006770769.1 410483223 13689591 complement(3191877..3193427) 1 NC_018650.1 hypothetical protein 3193427 13689591 O3M_15695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770769.1 3191877 R 1134782 CDS YP_006770770.1 410483224 13689592 3194976..3195410 1 NC_018650.1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); hypothetical protein 3195410 13689592 O3M_15700 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770770.1 3194976 D 1134782 CDS YP_006770771.1 410483225 13689593 3195563..3196543 1 NC_018650.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 3196543 13689593 O3M_15705 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006770771.1 3195563 D 1134782 CDS YP_006770772.1 410483226 13689594 3197158..3198423 1 NC_018650.1 COG2382 Enterochelin esterase and related enzymes; ferric enterochelin esterase 3198423 13689594 O3M_15710 Escherichia coli O104:H4 str. 2009EL-2050 ferric enterochelin esterase YP_006770772.1 3197158 D 1134782 CDS YP_006770773.1 410483227 13689595 complement(3198565..3199689) 1 NC_018650.1 COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; glucosyl-transferase 3199689 13689595 O3M_15715 Escherichia coli O104:H4 str. 2009EL-2050 glucosyl-transferase YP_006770773.1 3198565 R 1134782 CDS YP_006770774.1 410483228 13689596 complement(3200419..3200616) 1 NC_018650.1 COG3311 Predicted transcriptional regulator; DNA binding protein 3200616 13689596 O3M_15720 Escherichia coli O104:H4 str. 2009EL-2050 DNA binding protein YP_006770774.1 3200419 R 1134782 CDS YP_006770775.1 410483229 13689597 complement(3200682..3200876) 1 NC_018650.1 hypothetical protein 3200876 13689597 O3M_15725 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770775.1 3200682 R 1134782 CDS YP_006770776.1 410483230 13689598 3201098..3201181 1 NC_018650.1 hypothetical protein 3201181 13689598 O3M_15730 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770776.1 3201098 D 1134782 CDS YP_006770777.1 410483231 13689599 3201778..3201972 1 NC_018650.1 hypothetical protein 3201972 13689599 O3M_15735 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770777.1 3201778 D 1134782 CDS YP_006770778.1 410483232 13689600 3202333..3202461 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; hypothetical protein 3202461 13689600 O3M_15740 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770778.1 3202333 D 1134782 CDS YP_006770779.1 410483233 13689601 complement(3202943..3203107) 1 NC_018650.1 hypothetical protein 3203107 13689601 O3M_15745 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770779.1 3202943 R 1134782 CDS YP_006770780.1 410483234 13689602 complement(3203741..3203959) 1 NC_018650.1 hypothetical protein 3203959 13689602 O3M_15750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770780.1 3203741 R 1134782 CDS YP_006770781.1 410483235 13689603 complement(3205291..3205473) 1 NC_018650.1 hypothetical protein 3205473 13689603 O3M_15755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770781.1 3205291 R 1134782 CDS YP_006770782.1 410483236 13689604 3205412..3207502 1 NC_018650.1 COG4771 Outer membrane receptor for ferrienterochelin and colicins; bifunctional enterobactin receptor/adhesin protein 3207502 13689604 O3M_15760 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional enterobactin receptor/adhesin protein YP_006770782.1 3205412 D 1134782 CDS YP_006770783.1 410483237 13689605 3207736..3207960 1 NC_018650.1 hypothetical protein 3207960 13689605 O3M_15765 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770783.1 3207736 D 1134782 CDS YP_006770784.1 410483238 13689606 3208198..3208602 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; ISSfl3 protein 3208602 13689606 O3M_15770 Escherichia coli O104:H4 str. 2009EL-2050 ISSfl3 protein YP_006770784.1 3208198 D 1134782 CDS YP_006770785.1 410483239 13689607 3208599..3208946 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; IS66 family element 3208946 13689607 O3M_15775 Escherichia coli O104:H4 str. 2009EL-2050 IS66 family element YP_006770785.1 3208599 D 1134782 CDS YP_006770786.1 410483240 13689608 3210190..3210378 1 NC_018650.1 hypothetical protein 3210378 13689608 O3M_15790 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770786.1 3210190 D 1134782 CDS YP_006770787.1 410483241 13689609 complement(3210396..3212756) 1 NC_018650.1 COG4951 Uncharacterized protein conserved in bacteria; helicase 3212756 13689609 O3M_15795 Escherichia coli O104:H4 str. 2009EL-2050 helicase YP_006770787.1 3210396 R 1134782 CDS YP_006770788.1 410483242 13689610 complement(3212911..3213474) 1 NC_018650.1 hypothetical protein 3213474 13689610 O3M_15800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770788.1 3212911 R 1134782 CDS YP_006770789.1 410483243 13689611 complement(3214810..3216645) 1 NC_018650.1 hypothetical protein 3216645 13689611 O3M_15805 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770789.1 3214810 R 1134782 CDS YP_006770790.1 410483244 13689612 3216746..3217033 1 NC_018650.1 COG3311 Predicted transcriptional regulator; regulatory protein 3217033 13689612 O3M_15810 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein YP_006770790.1 3216746 D 1134782 CDS YP_006770791.1 410483245 13689613 3217008..3218534 1 NC_018650.1 hypothetical protein 3218534 13689613 O3M_15815 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770791.1 3217008 D 1134782 CDS YP_006770792.1 410483246 13689614 complement(3218704..3219921) 1 NC_018650.1 COG0582 Integrase; integrase 3219921 13689614 O3M_15820 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006770792.1 3218704 R 1134782 CDS YP_006770793.1 410483247 13689615 complement(3220469..3221455) 1 NC_018650.1 inner membrane protein 3221455 13689615 O3M_15825 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006770793.1 3220469 R 1134782 CDS YP_006770794.1 410483248 13689616 complement(3221452..3221997) 1 NC_018650.1 COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl CoA-ACP transacylase 3221997 13689616 O3M_15830 Escherichia coli O104:H4 str. 2009EL-2050 malonyl CoA-ACP transacylase YP_006770794.1 3221452 R 1134782 CDS YP_006770795.1 410483249 13689617 complement(3221984..3223342) 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 3223342 13689617 O3M_15835 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006770795.1 3221984 R 1134782 CDS YP_006770796.1 410483250 13689618 3223929..3226352 1 NC_018650.1 COG0457 FOG: TPR repeat; outer membrane protein PgaA 3226352 pgaA 13689618 pgaA Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein PgaA YP_006770796.1 3223929 D 1134782 CDS YP_006770797.1 410483251 13689619 3226361..3228379 1 NC_018650.1 COG0726 Predicted xylanase/chitin deacetylase; outer membrane N-deacetylase 3228379 pgaB 13689619 pgaB Escherichia coli O104:H4 str. 2009EL-2050 outer membrane N-deacetylase YP_006770797.1 3226361 D 1134782 CDS YP_006770798.1 410483252 13689620 3228372..3229697 1 NC_018650.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; N-glycosyltransferase 3229697 13689620 O3M_15850 Escherichia coli O104:H4 str. 2009EL-2050 N-glycosyltransferase YP_006770798.1 3228372 D 1134782 CDS YP_006770799.1 410483253 13689621 3229699..3230112 1 NC_018650.1 PGA biosynthesis protein 3230112 pgaD 13689621 pgaD Escherichia coli O104:H4 str. 2009EL-2050 PGA biosynthesis protein YP_006770799.1 3229699 D 1134782 CDS YP_006770800.1 410483254 13689622 complement(3230162..3230950) 1 NC_018650.1 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; hypothetical protein 3230950 13689622 O3M_15860 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770800.1 3230162 R 1134782 CDS YP_006770801.1 410483255 13689623 complement(3231569..3232840) 1 NC_018650.1 COG2837 Predicted iron-dependent peroxidase; hypothetical protein 3232840 13689623 O3M_15865 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770801.1 3231569 R 1134782 CDS YP_006770802.1 410483256 13689624 complement(3232846..3233973) 1 NC_018650.1 COG2822 Predicted periplasmic lipoprotein involved in iron transport; inactive ferrous ion transporter periplasmic protein EfeO 3233973 13689624 O3M_15870 Escherichia coli O104:H4 str. 2009EL-2050 inactive ferrous ion transporter periplasmic protein EfeO YP_006770802.1 3232846 R 1134782 CDS YP_006770803.1 410483257 13689625 complement(3234031..3234861) 1 NC_018650.1 COG0672 High-affinity Fe2+/Pb2+ permease; high-affinity Fe2+/Pb2+ permease 3234861 13689625 O3M_15875 Escherichia coli O104:H4 str. 2009EL-2050 high-affinity Fe2+/Pb2+ permease YP_006770803.1 3234031 R 1134782 CDS YP_006770804.1 410483258 13689626 complement(3235403..3236911) 1 NC_018650.1 COG0591 Na+/proline symporter; proline:sodium symporter PutP 3236911 13689626 O3M_15880 Escherichia coli O104:H4 str. 2009EL-2050 proline:sodium symporter PutP YP_006770804.1 3235403 R 1134782 CDS YP_006770805.1 410483259 13689627 complement(3237070..3237279) 1 NC_018650.1 hypothetical protein 3237279 13689627 O3M_15885 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770805.1 3237070 R 1134782 CDS YP_006770806.1 410483260 13689628 3237334..3241296 1 NC_018650.1 COG0506 Proline dehydrogenase; multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 3241296 putA 13689628 putA Escherichia coli O104:H4 str. 2009EL-2050 multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_006770806.1 3237334 D 1134782 CDS YP_006770807.1 410483261 13689629 complement(3241336..3241974) 1 NC_018650.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator RutR 3241974 13689629 O3M_15895 Escherichia coli O104:H4 str. 2009EL-2050 HTH-type transcriptional regulator RutR YP_006770807.1 3241336 R 1134782 CDS YP_006770808.1 410483262 13689630 3242262..3243353 1 NC_018650.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; monooxygenase of the alternative pyrimidine degradation pathway 3243353 13689630 O3M_15900 Escherichia coli O104:H4 str. 2009EL-2050 monooxygenase of the alternative pyrimidine degradation pathway YP_006770808.1 3242262 D 1134782 CDS YP_006770809.1 410483263 13689631 3243353..3244045 1 NC_018650.1 COG1335 Amidases related to nicotinamidase; hypothetical protein 3244045 13689631 O3M_15905 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770809.1 3243353 D 1134782 CDS YP_006770810.1 410483264 13689632 3244057..3244443 1 NC_018650.1 COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 3244443 13689632 O3M_15910 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770810.1 3244057 D 1134782 CDS YP_006770811.1 410483265 13689633 3244451..3245251 1 NC_018650.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); enzyme of the alternative pyrimidine degradation pathway 3245251 13689633 O3M_15915 Escherichia coli O104:H4 str. 2009EL-2050 enzyme of the alternative pyrimidine degradation pathway YP_006770811.1 3244451 D 1134782 CDS YP_006770812.1 410483266 13689634 3245261..3245851 1 NC_018650.1 COG0778 Nitroreductase; malonic semialdehyde reductase 3245851 13689634 O3M_15920 Escherichia coli O104:H4 str. 2009EL-2050 malonic semialdehyde reductase YP_006770812.1 3245261 D 1134782 CDS YP_006770813.1 410483267 13689635 3245862..3246356 1 NC_018650.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; flavin:NADH oxidoreductase subunit of alternative pyrimidine degradation pathway 3246356 13689635 O3M_15925 Escherichia coli O104:H4 str. 2009EL-2050 flavin:NADH oxidoreductase subunit of alternative pyrimidine degradation pathway YP_006770813.1 3245862 D 1134782 CDS YP_006770814.1 410483268 13689636 3246377..3247705 1 NC_018650.1 COG2233 Xanthine/uracil permeases; transporter 3247705 13689636 O3M_15930 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770814.1 3246377 D 1134782 CDS YP_006770815.1 410483269 13689637 complement(3247788..3247961) 1 NC_018650.1 COG3729 General stress protein; hypothetical protein 3247961 13689637 O3M_15935 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770815.1 3247788 R 1134782 CDS YP_006770817.1 410483271 13689639 complement(3248893..3257274) 1 NC_018650.1 hypothetical protein 3257274 13689639 O3M_15945 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770817.1 3248893 R 1134782 CDS YP_006770818.1 410483272 13689640 complement(3257344..3258609) 1 NC_018650.1 hypothetical protein 3258609 13689640 O3M_15950 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770818.1 3257344 R 1134782 CDS YP_006770819.1 410483273 13689641 complement(3258620..3258871) 1 NC_018650.1 hypothetical protein 3258871 13689641 O3M_15955 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770819.1 3258620 R 1134782 CDS YP_006770820.1 410483274 13689642 complement(3258881..3259327) 1 NC_018650.1 hypothetical protein 3259327 13689642 O3M_15960 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770820.1 3258881 R 1134782 CDS YP_006770821.1 410483275 13689643 complement(3259330..3259986) 1 NC_018650.1 hypothetical protein 3259986 13689643 O3M_15965 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770821.1 3259330 R 1134782 CDS YP_006770822.1 410483276 13689644 complement(3260081..3260482) 1 NC_018650.1 hypothetical protein 3260482 13689644 O3M_15970 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770822.1 3260081 R 1134782 CDS YP_006770823.1 410483277 13689645 complement(3260539..3260679) 1 NC_018650.1 hypothetical protein 3260679 13689645 O3M_15975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770823.1 3260539 R 1134782 CDS YP_006770824.1 410483278 13689646 complement(3260910..3261644) 1 NC_018650.1 outer membrane protein Lom 3261644 13689646 O3M_15980 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein Lom YP_006770824.1 3260910 R 1134782 CDS YP_006770825.1 410483279 13689647 complement(3261735..3262352) 1 NC_018650.1 hypothetical protein 3262352 13689647 O3M_15985 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770825.1 3261735 R 1134782 CDS YP_006770826.1 410483280 13689648 complement(3262358..3262636) 1 NC_018650.1 outer membrane protein 3262636 13689648 O3M_15990 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein YP_006770826.1 3262358 R 1134782 CDS YP_006770827.1 410483281 13689649 complement(3262651..3263919) 1 NC_018650.1 COG4733 Phage-related protein, tail component; tail tip fiber protein 3263919 13689649 O3M_15995 Escherichia coli O104:H4 str. 2009EL-2050 tail tip fiber protein YP_006770827.1 3262651 R 1134782 CDS YP_006770828.1 410483282 13689650 complement(3263916..3265607) 1 NC_018650.1 hypothetical protein 3265607 13689650 O3M_16000 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770828.1 3263916 R 1134782 CDS YP_006770829.1 410483283 13689651 complement(3265775..3266287) 1 NC_018650.1 hypothetical protein 3266287 13689651 O3M_16005 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770829.1 3265775 R 1134782 CDS YP_006770830.1 410483284 13689652 complement(3266374..3268965) 1 NC_018650.1 tail fiber protein 3268965 13689652 O3M_16010 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber protein YP_006770830.1 3266374 R 1134782 CDS YP_006770831.1 410483285 13689653 complement(3268962..3269612) 1 NC_018650.1 hypothetical protein 3269612 13689653 O3M_16015 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770831.1 3268962 R 1134782 CDS YP_006770832.1 410483286 13689654 complement(3269612..3270175) 1 NC_018650.1 hypothetical protein 3270175 13689654 O3M_16020 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770832.1 3269612 R 1134782 CDS YP_006770833.1 410483287 13689655 complement(3270159..3270620) 1 NC_018650.1 hypothetical protein 3270620 13689655 O3M_16025 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770833.1 3270159 R 1134782 CDS YP_006770834.1 410483288 13689656 complement(3270671..3271060) 1 NC_018650.1 hypothetical protein 3271060 13689656 O3M_16030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770834.1 3270671 R 1134782 CDS YP_006770835.1 410483289 13689657 complement(3271115..3272329) 1 NC_018650.1 hypothetical protein 3272329 13689657 O3M_16035 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770835.1 3271115 R 1134782 CDS YP_006770836.1 410483290 13689658 complement(3272353..3273360) 1 NC_018650.1 COG0061 Predicted sugar kinase; hypothetical protein 3273360 13689658 O3M_16040 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770836.1 3272353 R 1134782 CDS YP_006770837.1 410483291 13689659 complement(3273518..3275662) 1 NC_018650.1 portal protein 3275662 13689659 O3M_16045 Escherichia coli O104:H4 str. 2009EL-2050 portal protein YP_006770837.1 3273518 R 1134782 CDS YP_006770838.1 410483292 13689660 complement(3275662..3277368) 1 NC_018650.1 terminase large subunit 3277368 13689660 O3M_16050 Escherichia coli O104:H4 str. 2009EL-2050 terminase large subunit YP_006770838.1 3275662 R 1134782 CDS YP_006770839.1 410483293 13689661 complement(3277349..3278155) 1 NC_018650.1 terminase small subunit of bacteriophage BP-933W 3278155 13689661 O3M_16055 Escherichia coli O104:H4 str. 2009EL-2050 terminase small subunit of bacteriophage BP-933W YP_006770839.1 3277349 R 1134782 CDS YP_006770840.1 410483294 13689662 3278564..3278857 1 NC_018650.1 Bor protein 3278857 13689662 O3M_16060 Escherichia coli O104:H4 str. 2009EL-2050 Bor protein YP_006770840.1 3278564 D 1134782 CDS YP_006770841.1 410483295 13689663 complement(3278889..3279353) 1 NC_018650.1 endopeptidase 3279353 13689663 O3M_16065 Escherichia coli O104:H4 str. 2009EL-2050 endopeptidase YP_006770841.1 3278889 R 1134782 CDS YP_006770842.1 410483296 13689664 complement(3279361..3279495) 1 NC_018650.1 hypothetical protein 3279495 13689664 O3M_16070 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770842.1 3279361 R 1134782 CDS YP_006770843.1 410483297 13689665 complement(3279510..3280079) 1 NC_018650.1 antirepressor 3280079 13689665 O3M_16075 Escherichia coli O104:H4 str. 2009EL-2050 antirepressor YP_006770843.1 3279510 R 1134782 CDS YP_006770844.1 410483298 13689666 complement(3280354..3280887) 1 NC_018650.1 COG3772 Phage-related lysozyme (muraminidase); endolysin 3280887 13689666 O3M_16080 Escherichia coli O104:H4 str. 2009EL-2050 endolysin YP_006770844.1 3280354 R 1134782 CDS YP_006770845.1 410483299 13689667 complement(3280892..3281107) 1 NC_018650.1 holin protein 3281107 13689667 O3M_16085 Escherichia coli O104:H4 str. 2009EL-2050 holin protein YP_006770845.1 3280892 R 1134782 CDS YP_006770846.1 410483300 13689668 complement(3281185..3281430) 1 NC_018650.1 hypothetical protein 3281430 13689668 O3M_16090 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770846.1 3281185 R 1134782 CDS YP_006770847.1 410483301 13689669 complement(3281471..3281650) 1 NC_018650.1 hypothetical protein 3281650 13689669 O3M_16095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770847.1 3281471 R 1134782 CDS YP_006770848.1 410483302 13689670 complement(3281787..3283724) 1 NC_018650.1 hypothetical protein 3283724 13689670 O3M_16100 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770848.1 3281787 R 1134782 CDS YP_006770849.1 410483303 13689671 complement(3284210..3284479) 1 NC_018650.1 Shiga toxin 2 subunit B 3284479 13689671 O3M_16105 Escherichia coli O104:H4 str. 2009EL-2050 Shiga toxin 2 subunit B YP_006770849.1 3284210 R 1134782 CDS YP_006770850.1 410483304 13689672 complement(3284491..3285450) 1 NC_018650.1 Shiga toxin 2 subunit A 3285450 13689672 O3M_16110 Escherichia coli O104:H4 str. 2009EL-2050 Shiga toxin 2 subunit A YP_006770850.1 3284491 R 1134782 CDS YP_006770851.1 410483305 13689676 complement(3285833..3285931) 1 NC_018650.1 DNA adenine methyltransferase encoded by prophage 3285931 13689676 O3M_16115 Escherichia coli O104:H4 str. 2009EL-2050 DNA adenine methyltransferase encoded by prophage YP_006770851.1 3285833 R 1134782 CDS YP_006770852.1 410483306 13689677 complement(3286234..3286668) 1 NC_018650.1 antitermination protein Q 3286668 13689677 O3M_16120 Escherichia coli O104:H4 str. 2009EL-2050 antitermination protein Q YP_006770852.1 3286234 R 1134782 CDS YP_006770853.1 410483307 13689678 complement(3286661..3286855) 1 NC_018650.1 hypothetical protein 3286855 13689678 O3M_16125 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770853.1 3286661 R 1134782 CDS YP_006770854.1 410483308 13689679 complement(3286852..3287415) 1 NC_018650.1 hypothetical protein 3287415 13689679 O3M_16130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770854.1 3286852 R 1134782 CDS YP_006770855.1 410483309 13689680 complement(3287423..3287872) 1 NC_018650.1 hypothetical protein 3287872 13689680 O3M_16135 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770855.1 3287423 R 1134782 CDS YP_006770856.1 410483310 13689681 complement(3287872..3288843) 1 NC_018650.1 DNA primase 3288843 13689681 O3M_16140 Escherichia coli O104:H4 str. 2009EL-2050 DNA primase YP_006770856.1 3287872 R 1134782 CDS YP_006770857.1 410483311 13689682 complement(3288833..3290353) 1 NC_018650.1 COG1061 DNA or RNA helicases of superfamily II; helicase 3290353 13689682 O3M_16145 Escherichia coli O104:H4 str. 2009EL-2050 helicase YP_006770857.1 3288833 R 1134782 CDS YP_006770858.1 410483312 13689683 complement(3290347..3290724) 1 NC_018650.1 COG3480 Predicted secreted protein containing a PDZ domain; hypothetical protein 3290724 13689683 O3M_16150 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770858.1 3290347 R 1134782 CDS YP_006770859.1 410483313 13689684 complement(3290932..3291225) 1 NC_018650.1 hypothetical protein 3291225 13689684 O3M_16155 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770859.1 3290932 R 1134782 CDS YP_006770860.1 410483314 13689685 complement(3291256..3291459) 1 NC_018650.1 hypothetical protein 3291459 13689685 O3M_16160 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770860.1 3291256 R 1134782 CDS YP_006770861.1 410483315 13689686 3291555..3292268 1 NC_018650.1 COG2932 Predicted transcriptional regulator; repressor protein CI 3292268 13689686 O3M_16165 Escherichia coli O104:H4 str. 2009EL-2050 repressor protein CI YP_006770861.1 3291555 D 1134782 CDS YP_006770862.1 410483316 13689687 3292363..3293832 1 NC_018650.1 COG0286 Type I restriction-modification system methyltransferase subunit; site-specific DNA-methyltransferase 3293832 13689687 O3M_16170 Escherichia coli O104:H4 str. 2009EL-2050 site-specific DNA-methyltransferase YP_006770862.1 3292363 D 1134782 CDS YP_006770863.1 410483317 13689688 3293829..3294782 1 NC_018650.1 type II site-specific deoxyribonuclease 3294782 13689688 O3M_16175 Escherichia coli O104:H4 str. 2009EL-2050 type II site-specific deoxyribonuclease YP_006770863.1 3293829 D 1134782 CDS YP_006770864.1 410483318 13689689 3295538..3296185 1 NC_018650.1 COG3646 Uncharacterized phage-encoded protein; hypothetical protein 3296185 13689689 O3M_16180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770864.1 3295538 D 1134782 CDS YP_006770865.1 410483319 13689690 3296256..3296468 1 NC_018650.1 host killing protein 3296468 13689690 O3M_16185 Escherichia coli O104:H4 str. 2009EL-2050 host killing protein YP_006770865.1 3296256 D 1134782 CDS YP_006770866.1 410483320 13689691 3296540..3296761 1 NC_018650.1 hypothetical protein 3296761 13689691 O3M_16190 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770866.1 3296540 D 1134782 CDS YP_006770867.1 410483321 13689692 3296782..3297063 1 NC_018650.1 hypothetical protein 3297063 13689692 O3M_16195 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770867.1 3296782 D 1134782 CDS YP_006770868.1 410483322 13689693 3297080..3298030 1 NC_018650.1 COG3723 Recombinational DNA repair protein (RecE pathway); DNA recombination protein Bet 3298030 13689693 O3M_16200 Escherichia coli O104:H4 str. 2009EL-2050 DNA recombination protein Bet YP_006770868.1 3297080 D 1134782 CDS YP_006770869.1 410483323 13689694 3298027..3298716 1 NC_018650.1 COG4615 ABC-type siderophore export system, fused ATPase and permease components; exonuclease 3298716 13689694 O3M_16205 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease YP_006770869.1 3298027 D 1134782 CDS YP_006770870.1 410483324 13689695 3298716..3299303 1 NC_018650.1 hypothetical protein 3299303 13689695 O3M_16210 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770870.1 3298716 D 1134782 CDS YP_006770871.1 410483325 13689696 3299378..3299725 1 NC_018650.1 hypothetical protein 3299725 13689696 O3M_16215 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770871.1 3299378 D 1134782 CDS YP_006770872.1 410483326 13689697 3299789..3300610 1 NC_018650.1 COG5532 Uncharacterized conserved protein; hypothetical protein 3300610 13689697 O3M_16220 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770872.1 3299789 D 1134782 CDS YP_006770873.1 410483327 13689698 3300687..3301082 1 NC_018650.1 hypothetical protein 3301082 13689698 O3M_16225 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770873.1 3300687 D 1134782 CDS YP_006770874.1 410483328 13689699 3301233..3301958 1 NC_018650.1 hypothetical protein 3301958 13689699 O3M_16230 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770874.1 3301233 D 1134782 CDS YP_006770875.1 410483329 13689700 3301955..3302362 1 NC_018650.1 hypothetical protein 3302362 13689700 O3M_16235 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770875.1 3301955 D 1134782 CDS YP_006770876.1 410483330 13689701 3302364..3302555 1 NC_018650.1 hypothetical protein 3302555 13689701 O3M_16240 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770876.1 3302364 D 1134782 CDS YP_006770877.1 410483331 13689702 3302558..3303454 1 NC_018650.1 hypothetical protein 3303454 13689702 O3M_16245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770877.1 3302558 D 1134782 CDS YP_006770878.1 410483332 13689703 3303447..3303545 1 NC_018650.1 hypothetical protein 3303545 13689703 O3M_16250 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770878.1 3303447 D 1134782 CDS YP_006770879.1 410483333 13689704 3303810..3304094 1 NC_018650.1 COG3561 Phage anti-repressor protein; phage anti-repressor protein AntB 3304094 13689704 O3M_16255 Escherichia coli O104:H4 str. 2009EL-2050 phage anti-repressor protein AntB YP_006770879.1 3303810 D 1134782 CDS YP_006770880.1 410483334 13689705 3304344..3304973 1 NC_018650.1 COG3561 Phage anti-repressor protein; antirepressor 3304973 13689705 O3M_16260 Escherichia coli O104:H4 str. 2009EL-2050 antirepressor YP_006770880.1 3304344 D 1134782 CDS YP_006770881.1 410483335 13689706 3305104..3305460 1 NC_018650.1 regulatory protein 3305460 13689706 O3M_16265 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein YP_006770881.1 3305104 D 1134782 CDS YP_006770882.1 410483336 13689707 3305457..3306083 1 NC_018650.1 COG4725 Transcriptional activator, adenine-specific DNA methyltransferase; adenine methylase 3306083 13689707 O3M_16270 Escherichia coli O104:H4 str. 2009EL-2050 adenine methylase YP_006770882.1 3305457 D 1134782 CDS YP_006770883.1 410483337 13689708 3306043..3306255 1 NC_018650.1 hypothetical protein 3306255 13689708 O3M_16275 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770883.1 3306043 D 1134782 CDS YP_006770884.1 410483338 13689709 3306291..3306671 1 NC_018650.1 hypothetical protein 3306671 13689709 O3M_16280 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770884.1 3306291 D 1134782 CDS YP_006770885.1 410483339 13689710 3307035..3307286 1 NC_018650.1 hypothetical protein 3307286 13689710 O3M_16285 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770885.1 3307035 D 1134782 CDS YP_006770886.1 410483340 13689711 3307332..3307616 1 NC_018650.1 excisionase 3307616 13689711 O3M_16290 Escherichia coli O104:H4 str. 2009EL-2050 excisionase YP_006770886.1 3307332 D 1134782 CDS YP_006770887.1 410483341 13689712 3307669..3308979 1 NC_018650.1 COG0582 Integrase; integrase 3308979 13689712 O3M_16295 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006770887.1 3307669 D 1134782 CDS YP_006770888.1 410483342 13689713 3308976..3309554 1 NC_018650.1 COG0655 Multimeric flavodoxin WrbA; flavoprotein 3309554 13689713 O3M_16300 Escherichia coli O104:H4 str. 2009EL-2050 flavoprotein YP_006770888.1 3308976 D 1134782 CDS YP_006770889.1 410483343 13689714 3309575..3309802 1 NC_018650.1 hypothetical protein 3309802 13689714 O3M_16305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770889.1 3309575 D 1134782 CDS YP_006770890.1 410483344 13689715 complement(3309840..3311081) 1 NC_018650.1 glucose-1-phosphatase/inositol phosphatase 3311081 13689715 O3M_16310 Escherichia coli O104:H4 str. 2009EL-2050 glucose-1-phosphatase/inositol phosphatase YP_006770890.1 3309840 R 1134782 CDS YP_006770891.1 410483345 13689716 complement(3311370..3312557) 1 NC_018650.1 hypothetical protein 3312557 13689716 O3M_16315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770891.1 3311370 R 1134782 CDS YP_006770892.1 410483346 13689717 3312890..3313810 1 NC_018650.1 COG2214 DnaJ-class molecular chaperone; curved DNA-binding protein CbpA 3313810 13689717 O3M_16320 Escherichia coli O104:H4 str. 2009EL-2050 curved DNA-binding protein CbpA YP_006770892.1 3312890 D 1134782 CDS YP_006770893.1 410483347 13689718 3313810..3314115 1 NC_018650.1 chaperone-modulator protein CbpM 3314115 13689718 O3M_16325 Escherichia coli O104:H4 str. 2009EL-2050 chaperone-modulator protein CbpM YP_006770893.1 3313810 D 1134782 CDS YP_006770894.1 410483348 13689719 complement(3314208..3314807) 1 NC_018650.1 COG3381 Uncharacterized component of anaerobic dehydrogenases; chaperone protein TorD 3314807 torD 13689719 torD Escherichia coli O104:H4 str. 2009EL-2050 chaperone protein TorD YP_006770894.1 3314208 R 1134782 CDS YP_006770895.1 410483349 13689720 complement(3314804..3317350) 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; trimethylamine N-oxide reductase I catalytic subunit 3317350 13689720 O3M_16335 Escherichia coli O104:H4 str. 2009EL-2050 trimethylamine N-oxide reductase I catalytic subunit YP_006770895.1 3314804 R 1134782 CDS YP_006770896.1 410483350 13689721 complement(3317350..3318522) 1 NC_018650.1 COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; trimethylamine N-oxide reductase cytochrome c-type subunit 3318522 13689721 O3M_16340 Escherichia coli O104:H4 str. 2009EL-2050 trimethylamine N-oxide reductase cytochrome c-type subunit YP_006770896.1 3317350 R 1134782 CDS YP_006770897.1 410483351 13689722 3318652..3319344 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator TorR 3319344 13689722 O3M_16345 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator TorR YP_006770897.1 3318652 D 1134782 CDS YP_006770898.1 410483352 13689723 complement(3319317..3320345) 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; TMAO reductase system periplasmic protein TorT 3320345 13689723 O3M_16350 Escherichia coli O104:H4 str. 2009EL-2050 TMAO reductase system periplasmic protein TorT YP_006770898.1 3319317 R 1134782 CDS YP_006770899.1 410483353 13689724 3320428..3323172 1 NC_018650.1 COG0642 Signal transduction histidine kinase; hybrid sensory histidine kinase TorS 3323172 13689724 O3M_16355 Escherichia coli O104:H4 str. 2009EL-2050 hybrid sensory histidine kinase TorS YP_006770899.1 3320428 D 1134782 CDS YP_006770900.1 410483354 13689725 3323244..3324317 1 NC_018650.1 COG0348 Polyferredoxin; 4Fe-4S binding protein 3324317 13689725 O3M_16360 Escherichia coli O104:H4 str. 2009EL-2050 4Fe-4S binding protein YP_006770900.1 3323244 D 1134782 CDS YP_006770901.1 410483355 13689726 complement(3324366..3324539) 1 NC_018650.1 regulator of phosphatidylethanolamine synthesis 3324539 13689726 O3M_16365 Escherichia coli O104:H4 str. 2009EL-2050 regulator of phosphatidylethanolamine synthesis YP_006770901.1 3324366 R 1134782 CDS YP_006770902.1 410483356 13689727 complement(3324529..3324792) 1 NC_018650.1 cold shock protein 3324792 13689727 O3M_16370 Escherichia coli O104:H4 str. 2009EL-2050 cold shock protein YP_006770902.1 3324529 R 1134782 CDS YP_006770903.1 410483357 13689728 complement(3324933..3325145) 1 NC_018650.1 COG1278 Cold shock proteins; cold shock protein CspG 3325145 13689728 O3M_16375 Escherichia coli O104:H4 str. 2009EL-2050 cold shock protein CspG YP_006770903.1 3324933 R 1134782 CDS YP_006770904.1 410483358 13689729 3325431..3325643 1 NC_018650.1 COG1278 Cold shock proteins; cold shock-like protein CspH 3325643 13689729 O3M_16380 Escherichia coli O104:H4 str. 2009EL-2050 cold shock-like protein CspH YP_006770904.1 3325431 D 1134782 CDS YP_006770905.1 410483359 13689730 3326497..3327141 1 NC_018650.1 outer membrane lipoprotein 3327141 13689730 O3M_16385 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006770905.1 3326497 D 1134782 CDS YP_006770906.1 410483360 13689731 3327138..3327884 1 NC_018650.1 hypothetical protein 3327884 13689731 O3M_16390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770906.1 3327138 D 1134782 CDS YP_006770907.1 410483361 13689732 3327884..3329980 1 NC_018650.1 hypothetical protein 3329980 13689732 O3M_16395 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770907.1 3327884 D 1134782 CDS YP_006770908.1 410483362 13689733 3330026..3331165 1 NC_018650.1 COG1596 Periplasmic protein involved in polysaccharide export; polysaccharide export protein Wza 3331165 13689733 O3M_16400 Escherichia coli O104:H4 str. 2009EL-2050 polysaccharide export protein Wza YP_006770908.1 3330026 D 1134782 CDS YP_006770909.1 410483363 13689734 3331153..3331599 1 NC_018650.1 COG0394 Protein-tyrosine-phosphatase; phosphotyrosine-protein phosphatase 3331599 etp 13689734 etp Escherichia coli O104:H4 str. 2009EL-2050 phosphotyrosine-protein phosphatase YP_006770909.1 3331153 D 1134782 CDS YP_006770910.1 410483364 13689735 3331619..3333799 1 NC_018650.1 COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; cryptic autophosphorylating protein tyrosine kinase Etk 3333799 13689735 O3M_16410 Escherichia coli O104:H4 str. 2009EL-2050 cryptic autophosphorylating protein tyrosine kinase Etk YP_006770910.1 3331619 D 1134782 CDS YP_006770911.1 410483365 13689736 complement(3333914..3335212) 1 NC_018650.1 phosphoanhydride phosphorylase 3335212 13689736 O3M_16415 Escherichia coli O104:H4 str. 2009EL-2050 phosphoanhydride phosphorylase YP_006770911.1 3333914 R 1134782 CDS YP_006770912.1 410483366 13689737 complement(3335292..3335384) 1 NC_018650.1 hypothetical protein 3335384 13689737 O3M_16420 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770912.1 3335292 R 1134782 CDS YP_006770913.1 410483367 13689738 complement(3335397..3336533) 1 NC_018650.1 COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome bd-II oxidase subunit 2 3336533 13689738 O3M_16425 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome bd-II oxidase subunit 2 YP_006770913.1 3335397 R 1134782 CDS YP_006770914.1 410483368 13689739 complement(3336545..3338089) 1 NC_018650.1 COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome bd-II oxidase subunit 1 3338089 13689739 O3M_16430 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome bd-II oxidase subunit 1 YP_006770914.1 3336545 R 1134782 CDS YP_006770915.1 410483369 13689740 complement(3338223..3339080) 1 NC_018650.1 hydrogenase-1 operon protein HyaF 3339080 13689740 O3M_16435 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase-1 operon protein HyaF YP_006770915.1 3338223 R 1134782 CDS YP_006770916.1 410483370 13689741 complement(3339077..3339475) 1 NC_018650.1 COG0526 Thiol-disulfide isomerase and thioredoxins; hydrogenase-1 operon protein HyaE 3339475 13689741 O3M_16440 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase-1 operon protein HyaE YP_006770916.1 3339077 R 1134782 CDS YP_006770917.1 410483371 13689742 complement(3339472..3340059) 1 NC_018650.1 COG0680 Ni,Fe-hydrogenase maturation factor; hydrogenase 1 maturation protease 3340059 13689742 O3M_16445 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 1 maturation protease YP_006770917.1 3339472 R 1134782 CDS YP_006770918.1 410483372 13689743 complement(3340056..3340763) 1 NC_018650.1 COG1969 Ni,Fe-hydrogenase I cytochrome b subunit; hydrogenase 1 b-type cytochrome subunit 3340763 13689743 O3M_16450 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 1 b-type cytochrome subunit YP_006770918.1 3340056 R 1134782 CDS YP_006770919.1 410483373 13689744 complement(3340782..3342575) 1 NC_018650.1 COG0374 Ni,Fe-hydrogenase I large subunit; hydrogenase 1 large subunit 3342575 13689744 O3M_16455 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 1 large subunit YP_006770919.1 3340782 R 1134782 CDS YP_006770920.1 410483374 13689745 complement(3342572..3343690) 1 NC_018650.1 COG1740 Ni,Fe-hydrogenase I small subunit; hydrogenase 1, small subunit 3343690 13689745 O3M_16460 Escherichia coli O104:H4 str. 2009EL-2050 hydrogenase 1, small subunit YP_006770920.1 3342572 R 1134782 CDS YP_006770921.1 410483375 13689747 3344411..3345070 1 NC_018650.1 COG0670 Integral membrane protein, interacts with FtsH; HflBKC-binding inner membrane protein 3345070 13689747 O3M_16465 Escherichia coli O104:H4 str. 2009EL-2050 HflBKC-binding inner membrane protein YP_006770921.1 3344411 D 1134782 CDS YP_006770922.1 410483376 13689748 3345161..3345490 1 NC_018650.1 COG2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit; sulfur transfer protein TusE 3345490 13689748 O3M_16470 Escherichia coli O104:H4 str. 2009EL-2050 sulfur transfer protein TusE YP_006770922.1 3345161 D 1134782 CDS YP_006770923.1 410483377 13689749 complement(3345487..3345765) 1 NC_018650.1 COG1254 Acylphosphatases; acylphosphatase 3345765 13689749 O3M_16475 Escherichia coli O104:H4 str. 2009EL-2050 acylphosphatase YP_006770923.1 3345487 R 1134782 CDS YP_006770924.1 410483378 13689750 3345860..3347050 1 NC_018650.1 COG1092 Predicted SAM-dependent methyltransferases; 23S rRNA m(5)C1962 methyltransferase 3347050 13689750 O3M_16480 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA m(5)C1962 methyltransferase YP_006770924.1 3345860 D 1134782 CDS YP_006770925.1 410483379 13689751 3347108..3347425 1 NC_018650.1 COG3785 Uncharacterized conserved protein; heat shock protein HspQ 3347425 13689751 O3M_16485 Escherichia coli O104:H4 str. 2009EL-2050 heat shock protein HspQ YP_006770925.1 3347108 D 1134782 CDS YP_006770926.1 410483380 13689752 complement(3347470..3347883) 1 NC_018650.1 COG1832 Predicted CoA-binding protein; hypothetical protein 3347883 13689752 O3M_16490 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770926.1 3347470 R 1134782 CDS YP_006770927.1 410483381 13689753 3348056..3348718 1 NC_018650.1 COG3110 Uncharacterized protein conserved in bacteria; hypothetical protein 3348718 13689753 O3M_16495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770927.1 3348056 D 1134782 CDS YP_006770928.1 410483382 13689754 3348814..3349272 1 NC_018650.1 COG1803 Methylglyoxal synthase; methylglyoxal synthase 3349272 mgsA 13689754 mgsA Escherichia coli O104:H4 str. 2009EL-2050 methylglyoxal synthase YP_006770928.1 3348814 D 1134782 CDS YP_006770929.1 410483383 13689755 complement(3349304..3351358) 1 NC_018650.1 COG0210 Superfamily I DNA and RNA helicases; DNA helicase IV 3351358 helD 13689755 helD Escherichia coli O104:H4 str. 2009EL-2050 DNA helicase IV YP_006770929.1 3349304 R 1134782 CDS YP_006770930.1 410483384 13689756 3351481..3351927 1 NC_018650.1 COG3304 Predicted membrane protein; hypothetical protein 3351927 13689756 O3M_16510 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770930.1 3351481 D 1134782 CDS YP_006770931.1 410483385 13689757 3351937..3354099 1 NC_018650.1 COG1289 Predicted membrane protein; hypothetical protein 3354099 13689757 O3M_16515 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770931.1 3351937 D 1134782 CDS YP_006770932.1 410483386 13689758 complement(3354062..3354691) 1 NC_018650.1 COG3070 Regulator of competence-specific genes; hypothetical protein 3354691 13689758 O3M_16520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770932.1 3354062 R 1134782 CDS YP_006770933.1 410483387 13689759 3354910..3355419 1 NC_018650.1 COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation; SOS cell division inhibitor 3355419 13689759 O3M_16525 Escherichia coli O104:H4 str. 2009EL-2050 SOS cell division inhibitor YP_006770933.1 3354910 D 1134782 CDS YP_006770934.1 410483388 13689760 3355776..3356816 1 NC_018650.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; outer membrane protein A 3356816 13689760 O3M_16530 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein A YP_006770934.1 3355776 D 1134782 CDS YP_006770935.1 410483389 13689761 complement(3356892..3357344) 1 NC_018650.1 COG3120 Uncharacterized protein conserved in bacteria; Ter macrodomain organizer matS-binding protein 3357344 13689761 O3M_16535 Escherichia coli O104:H4 str. 2009EL-2050 Ter macrodomain organizer matS-binding protein YP_006770935.1 3356892 R 1134782 CDS YP_006770936.1 410483390 13689762 3357530..3359290 1 NC_018650.1 COG1067 Predicted ATP-dependent protease; peptidase, S16 (Lon protease) family protein 3359290 13689762 O3M_16540 Escherichia coli O104:H4 str. 2009EL-2050 peptidase, S16 (Lon protease) family protein YP_006770936.1 3357530 D 1134782 CDS YP_006770937.1 410483391 13689763 3359359..3359877 1 NC_018650.1 COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; 3-hydroxydecanoyl-ACP dehydratase 3359877 13689763 O3M_16545 Escherichia coli O104:H4 str. 2009EL-2050 3-hydroxydecanoyl-ACP dehydratase YP_006770937.1 3359359 D 1134782 CDS YP_006770938.1 410483392 13689764 complement(3359947..3360114) 1 NC_018650.1 COG3130 Ribosome modulation factor; ribosome modulation factor 3360114 13689764 O3M_16550 Escherichia coli O104:H4 str. 2009EL-2050 ribosome modulation factor YP_006770938.1 3359947 R 1134782 CDS YP_006770939.1 410483393 13689765 complement(3360370..3360933) 1 NC_018650.1 COG3009 Uncharacterized protein conserved in bacteria; lipoprotein 3360933 13689765 O3M_16555 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006770939.1 3360370 R 1134782 CDS YP_006770940.1 410483394 13689766 complement(3360930..3362570) 1 NC_018650.1 COG3008 Paraquat-inducible protein B; paraquat-inducible protein B 3362570 13689766 O3M_16560 Escherichia coli O104:H4 str. 2009EL-2050 paraquat-inducible protein B YP_006770940.1 3360930 R 1134782 CDS YP_006770941.1 410483395 13689767 complement(3362575..3363828) 1 NC_018650.1 COG2995 Uncharacterized paraquat-inducible protein A; paraquat-inducible membrane protein A 3363828 13689767 O3M_16565 Escherichia coli O104:H4 str. 2009EL-2050 paraquat-inducible membrane protein A YP_006770941.1 3362575 R 1134782 CDS YP_006770942.1 410483396 13689768 complement(3363958..3365865) 1 NC_018650.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 3365865 13689768 O3M_16570 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATPase YP_006770942.1 3363958 R 1134782 CDS YP_006770943.1 410483397 13689769 complement(3365876..3367984) 1 NC_018650.1 COG0116 Predicted N6-adenine-specific DNA methylase; 23S rRNA m(2)G2445 methyltransferase 3367984 rlmL 13689769 rlmL Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA m(2)G2445 methyltransferase YP_006770943.1 3365876 R 1134782 CDS YP_006770944.1 410483398 13689770 3368228..3369337 1 NC_018650.1 COG3217 Uncharacterized Fe-S protein; 2Fe-2S cluster-containing protein 3369337 13689770 O3M_16580 Escherichia coli O104:H4 str. 2009EL-2050 2Fe-2S cluster-containing protein YP_006770944.1 3368228 D 1134782 CDS YP_006770945.1 410483399 13689771 complement(3369334..3369876) 1 NC_018650.1 hypothetical protein 3369876 13689771 O3M_16585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770945.1 3369334 R 1134782 CDS YP_006770946.1 410483400 13689772 complement(3370050..3371060) 1 NC_018650.1 COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 2 3371060 13689772 O3M_16590 Escherichia coli O104:H4 str. 2009EL-2050 dihydroorotate dehydrogenase 2 YP_006770946.1 3370050 R 1134782 CDS YP_006770947.1 410483401 13689773 complement(3371171..3371881) 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; pili assembly chaperone 3371881 13689773 O3M_16595 Escherichia coli O104:H4 str. 2009EL-2050 pili assembly chaperone YP_006770947.1 3371171 R 1134782 CDS YP_006770948.1 410483402 13689774 complement(3371874..3372389) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial protein 3372389 13689774 O3M_16600 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein YP_006770948.1 3371874 R 1134782 CDS YP_006770949.1 410483403 13689775 complement(3372397..3372939) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 3372939 13689775 O3M_16605 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006770949.1 3372397 R 1134782 CDS YP_006770950.1 410483404 13689776 complement(3372951..3374021) 1 NC_018650.1 fimbrial-like adhesin protein 3374021 13689776 O3M_16610 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006770950.1 3372951 R 1134782 CDS YP_006770951.1 410483405 13689777 complement(3374012..3376612) 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein 3376612 13689777 O3M_16615 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane usher protein YP_006770951.1 3374012 R 1134782 CDS YP_006770952.1 410483406 13689778 complement(3376637..3377338) 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; periplasmic pilin chaperone 3377338 13689778 O3M_16620 Escherichia coli O104:H4 str. 2009EL-2050 periplasmic pilin chaperone YP_006770952.1 3376637 R 1134782 CDS YP_006770953.1 410483407 13689779 complement(3377421..3377963) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein 3377963 13689779 O3M_16625 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006770953.1 3377421 R 1134782 CDS YP_006770954.1 410483408 13689780 3378319..3378894 1 NC_018650.1 COG0431 Predicted flavoprotein; NAD(P)H-dependent FMN reductase 3378894 13689780 O3M_16630 Escherichia coli O104:H4 str. 2009EL-2050 NAD(P)H-dependent FMN reductase YP_006770954.1 3378319 D 1134782 CDS YP_006770955.1 410483409 13689781 3378887..3379846 1 NC_018650.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; alkanesulfonate transporter substrate-binding subunit 3379846 13689781 O3M_16635 Escherichia coli O104:H4 str. 2009EL-2050 alkanesulfonate transporter substrate-binding subunit YP_006770955.1 3378887 D 1134782 CDS YP_006770956.1 410483410 13689782 3379843..3380988 1 NC_018650.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkanesulfonate monooxygenase 3380988 13689782 O3M_16640 Escherichia coli O104:H4 str. 2009EL-2050 alkanesulfonate monooxygenase YP_006770956.1 3379843 D 1134782 CDS YP_006770957.1 410483411 13689783 3380999..3381790 1 NC_018650.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; alkanesulfonate transporter permease 3381790 ssuC 13689783 ssuC Escherichia coli O104:H4 str. 2009EL-2050 alkanesulfonate transporter permease YP_006770957.1 3380999 D 1134782 CDS YP_006770958.1 410483412 13689784 3381787..3382554 1 NC_018650.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; aliphatic sulfonates transport ATP-binding subunit 3382554 ssuB 13689784 ssuB Escherichia coli O104:H4 str. 2009EL-2050 aliphatic sulfonates transport ATP-binding subunit YP_006770958.1 3381787 D 1134782 CDS YP_006770959.1 410483413 13689785 complement(3382761..3385373) 1 NC_018650.1 COG0308 Aminopeptidase N; aminopeptidase N 3385373 pepN 13689785 pepN Escherichia coli O104:H4 str. 2009EL-2050 aminopeptidase N YP_006770959.1 3382761 R 1134782 CDS YP_006770960.1 410483414 13689786 3385639..3386841 1 NC_018650.1 COG1488 Nicotinic acid phosphoribosyltransferase; nicotinate phosphoribosyltransferase 3386841 13689786 O3M_16660 Escherichia coli O104:H4 str. 2009EL-2050 nicotinate phosphoribosyltransferase YP_006770960.1 3385639 D 1134782 CDS YP_006770961.1 410483415 13689787 3387010..3388410 1 NC_018650.1 COG0017 Aspartyl/asparaginyl-tRNA synthetases; asparaginyl-tRNA synthetase 3388410 asnC 13689787 asnC Escherichia coli O104:H4 str. 2009EL-2050 asparaginyl-tRNA synthetase YP_006770961.1 3387010 D 1134782 CDS YP_006770962.1 410483416 13689788 3389012..3390100 1 NC_018650.1 COG3203 Outer membrane protein (porin); outer membrane protein F 3390100 13689788 O3M_16670 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein F YP_006770962.1 3389012 D 1134782 CDS YP_006770963.1 410483417 13689789 complement(3390116..3390286) 1 NC_018650.1 hypothetical protein 3390286 13689789 O3M_16675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770963.1 3390116 R 1134782 CDS YP_006770964.1 410483418 13689790 3390285..3391475 1 NC_018650.1 COG1448 Aspartate/tyrosine/aromatic aminotransferase; aromatic amino acid aminotransferase 3391475 13689790 O3M_16680 Escherichia coli O104:H4 str. 2009EL-2050 aromatic amino acid aminotransferase YP_006770964.1 3390285 D 1134782 CDS YP_006770965.1 410483419 13689791 3391754..3392734 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 3392734 13689791 O3M_16685 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006770965.1 3391754 D 1134782 CDS YP_006770966.1 410483420 13689792 complement(3392976..3393623) 1 NC_018650.1 COG0491 Zn-dependent hydrolases, including glyoxylases; metal-binding enzyme 3393623 13689792 O3M_16690 Escherichia coli O104:H4 str. 2009EL-2050 metal-binding enzyme YP_006770966.1 3392976 R 1134782 CDS YP_006770967.1 410483421 13689793 complement(3393650..3394198) 1 NC_018650.1 COG3108 Uncharacterized protein conserved in bacteria; hypothetical protein 3394198 13689793 O3M_16695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770967.1 3393650 R 1134782 CDS YP_006770968.1 410483422 13689794 complement(3394379..3396226) 1 NC_018650.1 COG2989 Uncharacterized protein conserved in bacteria; murein L,D-transpeptidase 3396226 13689794 O3M_16700 Escherichia coli O104:H4 str. 2009EL-2050 murein L,D-transpeptidase YP_006770968.1 3394379 R 1134782 CDS YP_006770969.1 410483423 13689795 complement(3396487..3400947) 1 NC_018650.1 COG3096 Uncharacterized protein involved in chromosome partitioning; cell division protein MukB 3400947 mukB 13689795 mukB Escherichia coli O104:H4 str. 2009EL-2050 cell division protein MukB YP_006770969.1 3396487 R 1134782 CDS YP_006770970.1 410483424 13689796 complement(3400947..3401651) 1 NC_018650.1 COG3095 Uncharacterized protein involved in chromosome partitioning; condesin subunit E 3401651 13689796 O3M_16710 Escherichia coli O104:H4 str. 2009EL-2050 condesin subunit E YP_006770970.1 3400947 R 1134782 CDS YP_006770971.1 410483425 13689797 complement(3401632..3402954) 1 NC_018650.1 COG3006 Uncharacterized protein involved in chromosome partitioning; condesin subunit F 3402954 13689797 O3M_16715 Escherichia coli O104:H4 str. 2009EL-2050 condesin subunit F YP_006770971.1 3401632 R 1134782 CDS YP_006770972.1 410483426 13689798 complement(3402951..3403736) 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase 3403736 13689798 O3M_16720 Escherichia coli O104:H4 str. 2009EL-2050 S-adenosyl-L-methionine-dependent methyltransferase YP_006770972.1 3402951 R 1134782 CDS YP_006770973.1 410483427 13689799 3403872..3404651 1 NC_018650.1 COG1434 Uncharacterized conserved protein; hypothetical protein 3404651 13689799 O3M_16725 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770973.1 3403872 D 1134782 CDS YP_006770974.1 410483428 13689800 complement(3404628..3405521) 1 NC_018650.1 hypothetical protein 3405521 13689800 O3M_16730 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770974.1 3404628 R 1134782 CDS YP_006770975.1 410483429 13689801 complement(3405675..3406421) 1 NC_018650.1 COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; 3-deoxy-manno-octulosonate cytidylyltransferase 3406421 13689801 O3M_16735 Escherichia coli O104:H4 str. 2009EL-2050 3-deoxy-manno-octulosonate cytidylyltransferase YP_006770975.1 3405675 R 1134782 CDS YP_006770976.1 410483430 13689802 complement(3406418..3406600) 1 NC_018650.1 COG2835 Uncharacterized conserved protein; hypothetical protein 3406600 13689802 O3M_16740 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770976.1 3406418 R 1134782 CDS YP_006770977.1 410483431 13689803 complement(3406652..3407884) 1 NC_018650.1 COG3214 Uncharacterized protein conserved in bacteria; hypothetical protein 3407884 13689803 O3M_16745 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770977.1 3406652 R 1134782 CDS YP_006770978.1 410483432 13689804 complement(3407921..3408907) 1 NC_018650.1 COG1663 Tetraacyldisaccharide-1-P 4'-kinase; tetraacyldisaccharide 4'-kinase 3408907 lpxK 13689804 lpxK Escherichia coli O104:H4 str. 2009EL-2050 tetraacyldisaccharide 4'-kinase YP_006770978.1 3407921 R 1134782 CDS YP_006770979.1 410483433 13689805 complement(3408904..3410652) 1 NC_018650.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; lipid transporter ATP-binding protein/permease 3410652 13689805 O3M_16755 Escherichia coli O104:H4 str. 2009EL-2050 lipid transporter ATP-binding protein/permease YP_006770979.1 3408904 R 1134782 CDS YP_006770980.1 410483434 13689806 complement(3410689..3412953) 1 NC_018650.1 COG0658 Predicted membrane metal-binding protein; ComEC family competence protein 3412953 13689806 O3M_16760 Escherichia coli O104:H4 str. 2009EL-2050 ComEC family competence protein YP_006770980.1 3410689 R 1134782 CDS YP_006770981.1 410483435 13689807 complement(3413160..3413444) 1 NC_018650.1 COG0776 Bacterial nucleoid DNA-binding protein; integration host factor subunit beta 3413444 ihfB 13689807 ihfB Escherichia coli O104:H4 str. 2009EL-2050 integration host factor subunit beta YP_006770981.1 3413160 R 1134782 CDS YP_006770982.1 410483436 13689808 complement(3413604..3415277) 1 NC_018650.1 COG0539 Ribosomal protein S1; 30S ribosomal protein S1 3415277 rpsA 13689808 rpsA Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S1 YP_006770982.1 3413604 R 1134782 CDS YP_006770983.1 410483437 13689809 complement(3415388..3416071) 1 NC_018650.1 COG0283 Cytidylate kinase; cytidylate kinase 3416071 cmk 13689809 cmk Escherichia coli O104:H4 str. 2009EL-2050 cytidylate kinase YP_006770983.1 3415388 R 1134782 CDS YP_006770984.1 410483438 13689810 complement(3416244..3417008) 1 NC_018650.1 COG0501 Zn-dependent protease with chaperone function; heat shock protein 3417008 13689810 O3M_16780 Escherichia coli O104:H4 str. 2009EL-2050 heat shock protein YP_006770984.1 3416244 R 1134782 CDS YP_006770985.1 410483439 13689811 complement(3417177..3418460) 1 NC_018650.1 COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase 3418460 13689811 O3M_16785 Escherichia coli O104:H4 str. 2009EL-2050 3-phosphoshikimate 1-carboxyvinyltransferase YP_006770985.1 3417177 R 1134782 CDS YP_006770986.1 410483440 13689812 complement(3418531..3419619) 1 NC_018650.1 COG1932 Phosphoserine aminotransferase; 3-phosphoserine/phosphohydroxythreonine aminotransferase 3419619 13689812 O3M_16790 Escherichia coli O104:H4 str. 2009EL-2050 3-phosphoserine/phosphohydroxythreonine aminotransferase YP_006770986.1 3418531 R 1134782 CDS YP_006770987.1 410483441 13689813 complement(3419818..3420510) 1 NC_018650.1 COG2323 Predicted membrane protein; hypothetical protein 3420510 13689813 O3M_16795 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770987.1 3419818 R 1134782 CDS YP_006770988.1 410483442 13689814 3420640..3422400 1 NC_018650.1 COG1944 Uncharacterized conserved protein; hypothetical protein 3422400 13689814 O3M_16800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770988.1 3420640 D 1134782 CDS YP_006770989.1 410483443 13689815 3422805..3423662 1 NC_018650.1 COG2116 Formate/nitrite family of transporters; formate transporter 3423662 13689815 O3M_16805 Escherichia coli O104:H4 str. 2009EL-2050 formate transporter YP_006770989.1 3422805 D 1134782 CDS YP_006770990.1 410483444 13689816 3423717..3425999 1 NC_018650.1 COG1882 Pyruvate-formate lyase; formate acetyltransferase 3425999 13689816 O3M_16810 Escherichia coli O104:H4 str. 2009EL-2050 formate acetyltransferase YP_006770990.1 3423717 D 1134782 CDS YP_006770991.1 410483445 13689817 3426191..3426931 1 NC_018650.1 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase-activating enzyme 1 3426931 pflA 13689817 pflA Escherichia coli O104:H4 str. 2009EL-2050 pyruvate formate lyase-activating enzyme 1 YP_006770991.1 3426191 D 1134782 CDS YP_006770992.1 410483446 13689818 complement(3427013..3427603) 1 NC_018650.1 COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); hypothetical protein 3427603 13689818 O3M_16820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006770992.1 3427013 R 1134782 CDS YP_006770993.1 410483447 13689819 3427703..3428611 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 3428611 13689819 O3M_16825 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006770993.1 3427703 D 1134782 CDS YP_006770994.1 410483448 13689820 complement(3428612..3430042) 1 NC_018650.1 COG0531 Amino acid transporters; transporter 3430042 13689820 O3M_16830 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006770994.1 3428612 R 1134782 CDS YP_006770995.1 410483449 13689821 complement(3430252..3431400) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; MFS family transporter protein 3431400 13689821 O3M_16835 Escherichia coli O104:H4 str. 2009EL-2050 MFS family transporter protein YP_006770995.1 3430252 R 1134782 CDS YP_006770996.1 410483450 13689822 3431714..3432340 1 NC_018650.1 COG1335 Amidases related to nicotinamidase; hydrolase 3432340 13689822 O3M_16840 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006770996.1 3431714 D 1134782 CDS YP_006770997.1 410483451 13689823 complement(3432376..3433239) 1 NC_018650.1 COG3302 DMSO reductase anchor subunit; dimethyl sulfoxide reductase, anaerobic subunit C 3433239 13689823 O3M_16845 Escherichia coli O104:H4 str. 2009EL-2050 dimethyl sulfoxide reductase, anaerobic subunit C YP_006770997.1 3432376 R 1134782 CDS YP_006770998.1 410483452 13689824 complement(3433241..3433858) 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; anaerobic dimethyl sulfoxide reductase subunit B 3433858 13689824 O3M_16850 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic dimethyl sulfoxide reductase subunit B YP_006770998.1 3433241 R 1134782 CDS YP_006770999.1 410483453 13689825 complement(3433869..3436313) 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; anaerobic dimethyl sulfoxide reductase subunit A 3436313 13689825 O3M_16855 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic dimethyl sulfoxide reductase subunit A YP_006770999.1 3433869 R 1134782 CDS YP_006771000.1 410483454 13689826 complement(3436552..3437844) 1 NC_018650.1 COG0172 Seryl-tRNA synthetase; seryl-tRNA synthetase 3437844 13689826 O3M_16860 Escherichia coli O104:H4 str. 2009EL-2050 seryl-tRNA synthetase YP_006771000.1 3436552 R 1134782 CDS YP_006771001.1 410483455 13689827 complement(3437935..3439278) 1 NC_018650.1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA 3439278 13689827 O3M_16865 Escherichia coli O104:H4 str. 2009EL-2050 recombination factor protein RarA YP_006771001.1 3437935 R 1134782 CDS YP_006771002.1 410483456 13689828 complement(3439289..3439900) 1 NC_018650.1 COG2834 Outer membrane lipoprotein-sorting protein; lipoprotein chaperone 3439900 lolA 13689828 lolA Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein chaperone YP_006771002.1 3439289 R 1134782 CDS YP_006771003.1 410483457 13689829 complement(3440055..3444122) 1 NC_018650.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA translocase FtsK 3444122 13689829 O3M_16875 Escherichia coli O104:H4 str. 2009EL-2050 DNA translocase FtsK YP_006771003.1 3440055 R 1134782 CDS YP_006771004.1 410483458 13689830 complement(3444257..3444751) 1 NC_018650.1 COG1522 Transcriptional regulators; leucine-responsive transcriptional regulator 3444751 13689830 O3M_16880 Escherichia coli O104:H4 str. 2009EL-2050 leucine-responsive transcriptional regulator YP_006771004.1 3444257 R 1134782 CDS YP_006771005.1 410483459 13689831 3445296..3446261 1 NC_018650.1 COG0492 Thioredoxin reductase; thioredoxin reductase 3446261 13689831 O3M_16885 Escherichia coli O104:H4 str. 2009EL-2050 thioredoxin reductase YP_006771005.1 3445296 D 1134782 CDS YP_006771006.1 410483460 13689832 3446384..3448150 1 NC_018650.1 COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; cysteine/glutathione ABC transporter membrane/ATP-binding protein 3448150 13689832 O3M_16890 Escherichia coli O104:H4 str. 2009EL-2050 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_006771006.1 3446384 D 1134782 CDS YP_006771007.1 410483461 13689833 3448151..3449872 1 NC_018650.1 COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components; cysteine/glutathione ABC transporter membrane/ATP-binding protein 3449872 13689833 O3M_16895 Escherichia coli O104:H4 str. 2009EL-2050 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_006771007.1 3448151 D 1134782 CDS YP_006771008.1 410483462 13689834 3449914..3450618 1 NC_018650.1 COG2360 Leu/Phe-tRNA-protein transferase; leucyl/phenylalanyl-tRNA--protein transferase 3450618 aat 13689834 aat Escherichia coli O104:H4 str. 2009EL-2050 leucyl/phenylalanyl-tRNA--protein transferase YP_006771008.1 3449914 D 1134782 CDS YP_006771009.1 410483463 13689835 3450903..3451121 1 NC_018650.1 COG0361 Translation initiation factor 1 (IF-1); translation initiation factor IF-1 3451121 infA 13689835 infA Escherichia coli O104:H4 str. 2009EL-2050 translation initiation factor IF-1 YP_006771009.1 3450903 D 1134782 CDS YP_006771010.1 410483464 13689837 complement(3451806..3454082) 1 NC_018650.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit 3454082 clpA 13689837 clpA Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent Clp protease ATP-binding subunit YP_006771010.1 3451806 R 1134782 CDS YP_006771011.1 410483465 13689838 complement(3454113..3454433) 1 NC_018650.1 COG2127 Uncharacterized conserved protein; ATP-dependent Clp protease adaptor protein ClpS 3454433 clpS 13689838 clpS Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent Clp protease adaptor protein ClpS YP_006771011.1 3454113 R 1134782 CDS YP_006771012.1 410483466 13689839 3454756..3454980 1 NC_018650.1 COG1278 Cold shock proteins; stationary phase/starvation inducible regulatory protein CspD 3454980 13689839 O3M_16920 Escherichia coli O104:H4 str. 2009EL-2050 stationary phase/starvation inducible regulatory protein CspD YP_006771012.1 3454756 D 1134782 CDS YP_006771013.1 410483467 13689840 complement(3455053..3456999) 1 NC_018650.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; macrolide transporter ATP-binding /permease 3456999 13689840 O3M_16925 Escherichia coli O104:H4 str. 2009EL-2050 macrolide transporter ATP-binding /permease YP_006771013.1 3455053 R 1134782 CDS YP_006771014.1 410483468 13689841 complement(3456996..3458111) 1 NC_018650.1 COG0845 Membrane-fusion protein; macrolide transporter subunit MacA 3458111 13689841 O3M_16930 Escherichia coli O104:H4 str. 2009EL-2050 macrolide transporter subunit MacA YP_006771014.1 3456996 R 1134782 CDS YP_006771015.1 410483469 13689842 3458226..3459218 1 NC_018650.1 COG2990 Uncharacterized protein conserved in bacteria; hypothetical protein 3459218 13689842 O3M_16935 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771015.1 3458226 D 1134782 CDS YP_006771016.1 410483470 13689843 complement(3459215..3460873) 1 NC_018650.1 COG3593 Predicted ATP-dependent endonuclease of the OLD family; OLD family ATP-dependent endonuclease 3460873 13689843 O3M_16940 Escherichia coli O104:H4 str. 2009EL-2050 OLD family ATP-dependent endonuclease YP_006771016.1 3459215 R 1134782 CDS YP_006771017.1 410483471 13689844 3461299..3461994 1 NC_018650.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); aquaporin Z 3461994 13689844 O3M_16945 Escherichia coli O104:H4 str. 2009EL-2050 aquaporin Z YP_006771017.1 3461299 D 1134782 CDS YP_006771018.1 410483472 13689845 3462489..3463388 1 NC_018650.1 COG2431 Predicted membrane protein; transporter 3463388 13689845 O3M_16950 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771018.1 3462489 D 1134782 CDS YP_006771019.1 410483473 13689846 3463532..3465184 1 NC_018650.1 COG1151 6Fe-6S prismane cluster-containing protein; hybrid cluster protein 3465184 13689846 O3M_16955 Escherichia coli O104:H4 str. 2009EL-2050 hybrid cluster protein YP_006771019.1 3463532 D 1134782 CDS YP_006771020.1 410483474 13689847 3465196..3466164 1 NC_018650.1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; HCP oxidoreductase 3466164 13689847 O3M_16960 Escherichia coli O104:H4 str. 2009EL-2050 HCP oxidoreductase YP_006771020.1 3465196 D 1134782 CDS YP_006771021.1 410483475 13689848 3466297..3468015 1 NC_018650.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; pyruvate dehydrogenase 3468015 13689848 O3M_16965 Escherichia coli O104:H4 str. 2009EL-2050 pyruvate dehydrogenase YP_006771021.1 3466297 D 1134782 CDS YP_006771022.1 410483476 13689849 3468052..3469053 1 NC_018650.1 COG2008 Threonine aldolase; L-threonine aldolase 3469053 13689849 O3M_16970 Escherichia coli O104:H4 str. 2009EL-2050 L-threonine aldolase YP_006771022.1 3468052 D 1134782 CDS YP_006771023.1 410483477 13689850 3469064..3470494 1 NC_018650.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 3470494 13689850 O3M_16975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771023.1 3469064 D 1134782 CDS YP_006771024.1 410483478 13689851 3470593..3471606 1 NC_018650.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD dependent epimerase/dehydratase family protein 3471606 13689851 O3M_16980 Escherichia coli O104:H4 str. 2009EL-2050 NAD dependent epimerase/dehydratase family protein YP_006771024.1 3470593 D 1134782 CDS YP_006771025.1 410483479 13689852 complement(3471603..3472433) 1 NC_018650.1 COG3023 Negative regulator of beta-lactamase expression; N-acetylmuramoyl-L-alanine amidase AmiD 3472433 13689852 O3M_16985 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmuramoyl-L-alanine amidase AmiD YP_006771025.1 3471603 R 1134782 CDS YP_006771026.1 410483480 13689853 complement(3472430..3472753) 1 NC_018650.1 COG0393 Uncharacterized conserved protein; hypothetical protein 3472753 13689853 O3M_16990 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771026.1 3472430 R 1134782 CDS YP_006771027.1 410483481 13689854 3472879..3473394 1 NC_018650.1 COG0174 Glutamine synthetase; lipoprotein 3473394 13689854 O3M_16995 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006771027.1 3472879 D 1134782 CDS YP_006771028.1 410483482 13689855 3473612..3474340 1 NC_018650.1 COG4161 ABC-type arginine transport system, ATPase component; arginine transporter ATP-binding subunit 3474340 artP 13689855 artP Escherichia coli O104:H4 str. 2009EL-2050 arginine transporter ATP-binding subunit YP_006771028.1 3473612 D 1134782 CDS YP_006771029.1 410483483 13689856 3474358..3475089 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; arginine ABC transporter substrate-binding protein 3475089 13689856 O3M_17005 Escherichia coli O104:H4 str. 2009EL-2050 arginine ABC transporter substrate-binding protein YP_006771029.1 3474358 D 1134782 CDS YP_006771030.1 410483484 13689857 3475096..3475812 1 NC_018650.1 COG4215 ABC-type arginine transport system, permease component; arginine transporter permease subunit ArtQ 3475812 13689857 O3M_17010 Escherichia coli O104:H4 str. 2009EL-2050 arginine transporter permease subunit ArtQ YP_006771030.1 3475096 D 1134782 CDS YP_006771031.1 410483485 13689858 3475812..3476480 1 NC_018650.1 COG4160 ABC-type arginine/histidine transport system, permease component; arginine transporter permease subunit ArtM 3476480 artM 13689858 artM Escherichia coli O104:H4 str. 2009EL-2050 arginine transporter permease subunit ArtM YP_006771031.1 3475812 D 1134782 CDS YP_006771032.1 410483486 13689859 3476772..3477503 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; arginine 3rd transport system periplasmic binding protein ArtJ 3477503 13689859 O3M_17020 Escherichia coli O104:H4 str. 2009EL-2050 arginine 3rd transport system periplasmic binding protein ArtJ YP_006771032.1 3476772 D 1134782 CDS YP_006771033.1 410483487 13689860 complement(3477678..3478805) 1 NC_018650.1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; 23S rRNA methyluridine methyltransferase 3478805 rumB 13689860 rumB Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA methyluridine methyltransferase YP_006771033.1 3477678 R 1134782 CDS YP_006771034.1 410483488 13689861 complement(3478846..3479334) 1 NC_018650.1 inner membrane protein 3479334 13689861 O3M_17030 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771034.1 3478846 R 1134782 CDS YP_006771035.1 410483489 13689862 complement(3479394..3480239) 1 NC_018650.1 COG1177 ABC-type spermidine/putrescine transport system, permease component II; putrescine ABC transporter permease 3480239 13689862 O3M_17035 Escherichia coli O104:H4 str. 2009EL-2050 putrescine ABC transporter permease YP_006771035.1 3479394 R 1134782 CDS YP_006771036.1 410483490 13689863 complement(3480236..3481189) 1 NC_018650.1 COG1176 ABC-type spermidine/putrescine transport system, permease component I; putrescine ABC transporter permease 3481189 13689863 O3M_17040 Escherichia coli O104:H4 str. 2009EL-2050 putrescine ABC transporter permease YP_006771036.1 3480236 R 1134782 CDS YP_006771037.1 410483491 13689864 complement(3481199..3482332) 1 NC_018650.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; putrescine ABC transporter ATP-binding protein 3482332 potG 13689864 potG Escherichia coli O104:H4 str. 2009EL-2050 putrescine ABC transporter ATP-binding protein YP_006771037.1 3481199 R 1134782 CDS YP_006771038.1 410483492 13689865 complement(3482427..3483539) 1 NC_018650.1 COG0687 Spermidine/putrescine-binding periplasmic protein; putrescine ABC transporter substrate-binding protein 3483539 13689865 O3M_17050 Escherichia coli O104:H4 str. 2009EL-2050 putrescine ABC transporter substrate-binding protein YP_006771038.1 3482427 R 1134782 CDS YP_006771039.1 410483493 13689866 complement(3483891..3484367) 1 NC_018650.1 sensory transduction regulator 3484367 13689866 O3M_17055 Escherichia coli O104:H4 str. 2009EL-2050 sensory transduction regulator YP_006771039.1 3483891 R 1134782 CDS YP_006771040.1 410483494 13689867 complement(3484455..3485357) 1 NC_018650.1 COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); ribosomal protein S6 modification protein 3485357 13689867 O3M_17060 Escherichia coli O104:H4 str. 2009EL-2050 ribosomal protein S6 modification protein YP_006771040.1 3484455 R 1134782 CDS YP_006771041.1 410483495 13689868 complement(3485418..3486140) 1 NC_018650.1 COG0778 Nitroreductase; nitroreductase A 3486140 13689868 O3M_17065 Escherichia coli O104:H4 str. 2009EL-2050 nitroreductase A YP_006771041.1 3485418 R 1134782 CDS YP_006771042.1 410483496 13689869 complement(3486124..3486411) 1 NC_018650.1 hypothetical protein 3486411 13689869 O3M_17070 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771042.1 3486124 R 1134782 CDS YP_006771043.1 410483497 13689870 3486571..3486828 1 NC_018650.1 COG0695 Glutaredoxin and related proteins; glutaredoxin 3486828 grxA 13689870 grxA Escherichia coli O104:H4 str. 2009EL-2050 glutaredoxin YP_006771043.1 3486571 D 1134782 CDS YP_006771044.1 410483498 13689871 complement(3486858..3487235) 1 NC_018650.1 hypothetical protein 3487235 13689871 O3M_17080 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771044.1 3486858 R 1134782 CDS YP_006771045.1 410483499 13689872 3487505..3489190 1 NC_018650.1 COG2985 Predicted permease; transporter 3489190 13689872 O3M_17085 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771045.1 3487505 D 1134782 CDS YP_006771046.1 410483500 13689873 complement(3489365..3489901) 1 NC_018650.1 COG3226 Uncharacterized protein conserved in bacteria; DNA-binding transcriptional regulator 3489901 13689873 O3M_17090 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771046.1 3489365 R 1134782 CDS YP_006771047.1 410483501 13689874 3489985..3491193 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 3491193 13689874 O3M_17095 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771047.1 3489985 D 1134782 CDS YP_006771048.1 410483502 13689875 3491193..3492008 1 NC_018650.1 COG0561 Predicted hydrolases of the HAD superfamily; phosphatase 3492008 13689875 O3M_17100 Escherichia coli O104:H4 str. 2009EL-2050 phosphatase YP_006771048.1 3491193 D 1134782 CDS YP_006771049.1 410483503 13689876 3492094..3492378 1 NC_018650.1 hypothetical protein 3492378 13689876 O3M_17105 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771049.1 3492094 D 1134782 CDS YP_006771050.1 410483504 13689877 complement(3492419..3493651) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; multidrug efflux system translocase MdfA 3493651 13689877 O3M_17110 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system translocase MdfA YP_006771050.1 3492419 R 1134782 CDS YP_006771051.1 410483505 13689878 3493936..3494532 1 NC_018650.1 COG0671 Membrane-associated phospholipid phosphatase; undecaprenyl pyrophosphate phosphatase 3494532 13689878 O3M_17115 Escherichia coli O104:H4 str. 2009EL-2050 undecaprenyl pyrophosphate phosphatase YP_006771051.1 3493936 D 1134782 CDS YP_006771052.1 410483506 13689879 3494590..3495348 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DNA-binding transcriptional repressor DeoR 3495348 13689879 O3M_17120 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor DeoR YP_006771052.1 3494590 D 1134782 CDS YP_006771053.1 410483507 13689880 complement(3495395..3496597) 1 NC_018650.1 COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 3496597 13689880 O3M_17125 Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-D-alanine carboxypeptidase YP_006771053.1 3495395 R 1134782 CDS YP_006771054.1 410483508 13689881 3496844..3497470 1 NC_018650.1 COG0625 Glutathione S-transferase; transferase 3497470 13689881 O3M_17130 Escherichia coli O104:H4 str. 2009EL-2050 transferase YP_006771054.1 3496844 D 1134782 CDS YP_006771055.1 410483509 13689882 complement(3497467..3498582) 1 NC_018650.1 COG2133 Glucose/sorbosone dehydrogenases; dehydrogenase 3498582 13689882 O3M_17135 Escherichia coli O104:H4 str. 2009EL-2050 dehydrogenase YP_006771055.1 3497467 R 1134782 CDS YP_006771056.1 410483510 13689883 complement(3498693..3499076) 1 NC_018650.1 biofilm formation regulatory protein BssR 3499076 bssR 13689883 bssR Escherichia coli O104:H4 str. 2009EL-2050 biofilm formation regulatory protein BssR YP_006771056.1 3498693 R 1134782 CDS YP_006771057.1 410483511 13689884 3499289..3500614 1 NC_018650.1 COG0621 2-methylthioadenine synthetase; 30S ribosomal protein S12 methylthiotransferase 3500614 rimO 13689884 rimO Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S12 methylthiotransferase YP_006771057.1 3499289 D 1134782 CDS YP_006771058.1 410483512 13689885 complement(3500661..3501989) 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 3501989 13689885 O3M_17150 Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase YP_006771058.1 3500661 R 1134782 CDS YP_006771059.1 410483513 13689886 complement(3501997..3504345) 1 NC_018650.1 COG2200 FOG: EAL domain; hypothetical protein 3504345 13689886 O3M_17155 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771059.1 3501997 R 1134782 CDS YP_006771060.1 410483514 13689887 complement(3504523..3505434) 1 NC_018650.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; glutathione ABC transporter permease GsiD 3505434 13689887 O3M_17160 Escherichia coli O104:H4 str. 2009EL-2050 glutathione ABC transporter permease GsiD YP_006771060.1 3504523 R 1134782 CDS YP_006771061.1 410483515 13689888 complement(3505437..3506357) 1 NC_018650.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; glutathione ABC transporter permease GsiC 3506357 13689888 O3M_17165 Escherichia coli O104:H4 str. 2009EL-2050 glutathione ABC transporter permease GsiC YP_006771061.1 3505437 R 1134782 CDS YP_006771062.1 410483516 13689889 complement(3506375..3507913) 1 NC_018650.1 COG0747 ABC-type dipeptide transport system, periplasmic component; glutathione ABC transporter substrate-binding protein GsiB 3507913 13689889 O3M_17170 Escherichia coli O104:H4 str. 2009EL-2050 glutathione ABC transporter substrate-binding protein GsiB YP_006771062.1 3506375 R 1134782 CDS YP_006771063.1 410483517 13689890 complement(3507933..3509804) 1 NC_018650.1 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; glutathione transporter ATP-binding protein 3509804 13689890 O3M_17175 Escherichia coli O104:H4 str. 2009EL-2050 glutathione transporter ATP-binding protein YP_006771063.1 3507933 R 1134782 CDS YP_006771064.1 410483518 13689891 complement(3509791..3510756) 1 NC_018650.1 COG1446 Asparaginase; isoaspartyl peptidase 3510756 13689891 O3M_17180 Escherichia coli O104:H4 str. 2009EL-2050 isoaspartyl peptidase YP_006771064.1 3509791 R 1134782 CDS YP_006771065.1 410483519 13689892 3510960..3512195 1 NC_018650.1 COG0303 Molybdopterin biosynthesis enzyme; molybdopterin biosynthesis protein MoeA 3512195 13689892 O3M_17185 Escherichia coli O104:H4 str. 2009EL-2050 molybdopterin biosynthesis protein MoeA YP_006771065.1 3510960 D 1134782 CDS YP_006771066.1 410483520 13689893 3512195..3512944 1 NC_018650.1 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; molybdopterin biosynthesis protein MoeB 3512944 13689893 O3M_17190 Escherichia coli O104:H4 str. 2009EL-2050 molybdopterin biosynthesis protein MoeB YP_006771066.1 3512195 D 1134782 CDS YP_006771067.1 410483521 13689894 complement(3513032..3513694) 1 NC_018650.1 COG0176 Transaldolase; fructose-6-phosphate aldolase 3513694 13689894 O3M_17195 Escherichia coli O104:H4 str. 2009EL-2050 fructose-6-phosphate aldolase YP_006771067.1 3513032 R 1134782 CDS YP_006771068.1 410483522 13689895 3513825..3514724 1 NC_018650.1 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate-lyase 3 activating protein 3514724 13689895 O3M_17200 Escherichia coli O104:H4 str. 2009EL-2050 pyruvate formate-lyase 3 activating protein YP_006771068.1 3513825 D 1134782 CDS YP_006771069.1 410483523 13689896 3514730..3517162 1 NC_018650.1 COG1882 Pyruvate-formate lyase; pyruvate formate lyase 3517162 13689896 O3M_17205 Escherichia coli O104:H4 str. 2009EL-2050 pyruvate formate lyase YP_006771069.1 3514730 D 1134782 CDS YP_006771070.1 410483524 13689897 3517308..3518123 1 NC_018650.1 COG0561 Predicted hydrolases of the HAD superfamily; hydrolase 3518123 13689897 O3M_17210 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006771070.1 3517308 D 1134782 CDS YP_006771071.1 410483525 13689898 3518275..3519540 1 NC_018650.1 hypothetical protein 3519540 13689898 O3M_17215 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771071.1 3518275 D 1134782 CDS YP_006771072.1 410483526 13689899 complement(3519796..3520776) 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 3520776 13689899 O3M_17220 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006771072.1 3519796 R 1134782 CDS YP_006771073.1 410483527 13689900 complement(3521055..3522647) 1 NC_018650.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 3522647 13689900 O3M_17225 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006771073.1 3521055 R 1134782 CDS YP_006771074.1 410483528 13689901 3522866..3523786 1 NC_018650.1 COG1376 Uncharacterized protein conserved in bacteria; L,D-transpeptidase 3523786 13689901 O3M_17230 Escherichia coli O104:H4 str. 2009EL-2050 L,D-transpeptidase YP_006771074.1 3522866 D 1134782 CDS YP_006771075.1 410483529 13689902 complement(3523845..3524963) 1 NC_018650.1 COG0471 Di- and tricarboxylate transporters; transporter 3524963 13689902 O3M_17235 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771075.1 3523845 R 1134782 CDS YP_006771076.1 410483530 13689903 complement(3524960..3525427) 1 NC_018650.1 COG1321 Mn-dependent transcriptional regulator; manganese transport regulator MntR 3525427 13689903 O3M_17240 Escherichia coli O104:H4 str. 2009EL-2050 manganese transport regulator MntR YP_006771076.1 3524960 R 1134782 CDS YP_006771077.1 410483531 13689904 3526013..3527596 1 NC_018650.1 COG2194 Predicted membrane-associated, metal-dependent hydrolase; hydrolase, inner membrane 3527596 13689904 O3M_17245 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase, inner membrane YP_006771077.1 3526013 D 1134782 CDS YP_006771078.1 410483532 13689905 complement(3527645..3528160) 1 NC_018650.1 COG3637 Opacity protein and related surface antigens; outer membrane protein X 3528160 ompX 13689905 ompX Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein X YP_006771078.1 3527645 R 1134782 CDS YP_006771079.1 410483533 13689906 3528513..3529400 1 NC_018650.1 COG5006 Predicted permease, DMT superfamily; threonine and homoserine efflux system 3529400 13689906 O3M_17255 Escherichia coli O104:H4 str. 2009EL-2050 threonine and homoserine efflux system YP_006771079.1 3528513 D 1134782 CDS YP_006771080.1 410483534 13689907 3529699..3530202 1 NC_018650.1 COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); DNA starvation/stationary phase protection protein Dps 3530202 13689907 O3M_17260 Escherichia coli O104:H4 str. 2009EL-2050 DNA starvation/stationary phase protection protein Dps YP_006771080.1 3529699 D 1134782 CDS YP_006771081.1 410483535 13689908 3530606..3531352 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamine ABC transporter substrate-binding protein 3531352 glnH 13689908 glnH Escherichia coli O104:H4 str. 2009EL-2050 glutamine ABC transporter substrate-binding protein YP_006771081.1 3530606 D 1134782 CDS YP_006771082.1 410483536 13689909 3531491..3532150 1 NC_018650.1 COG0765 ABC-type amino acid transport system, permease component; glutamine ABC transporter permease 3532150 glnP 13689909 glnP Escherichia coli O104:H4 str. 2009EL-2050 glutamine ABC transporter permease YP_006771082.1 3531491 D 1134782 CDS YP_006771083.1 410483537 13689910 3532147..3532869 1 NC_018650.1 COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein 3532869 glnQ 13689910 glnQ Escherichia coli O104:H4 str. 2009EL-2050 glutamine ABC transporter ATP-binding protein YP_006771083.1 3532147 D 1134782 CDS YP_006771084.1 410483538 13690137 3532986..3535211 1 NC_018650.1 COG0668 Small-conductance mechanosensitive channel; mechanosensitive channel protein 3535211 13690137 O3M_17280 Escherichia coli O104:H4 str. 2009EL-2050 mechanosensitive channel protein YP_006771084.1 3532986 D 1134782 CDS YP_006771085.1 410483539 13690138 complement(3535208..3536134) 1 NC_018650.1 COG3129 Predicted SAM-dependent methyltransferase; 23S rRNA mA1618 methyltransferase 3536134 13690138 O3M_17285 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA mA1618 methyltransferase YP_006771085.1 3535208 R 1134782 CDS YP_006771086.1 410483540 13690139 3536266..3536670 1 NC_018650.1 hypothetical protein 3536670 13690139 O3M_17290 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771086.1 3536266 D 1134782 CDS YP_006771087.1 410483541 13690140 3536935..3539217 1 NC_018650.1 COG4774 Outer membrane receptor for monomeric catechols; catecholate siderophore receptor Fiu 3539217 13690140 O3M_17295 Escherichia coli O104:H4 str. 2009EL-2050 catecholate siderophore receptor Fiu YP_006771087.1 3536935 D 1134782 CDS YP_006771088.1 410483542 13690141 3539259..3539936 1 NC_018650.1 COG3128 Uncharacterized iron-regulated protein; Fe(II)-dependent oxygenase superfamily protein 3539936 13690141 O3M_17300 Escherichia coli O104:H4 str. 2009EL-2050 Fe(II)-dependent oxygenase superfamily protein YP_006771088.1 3539259 D 1134782 CDS YP_006771089.1 410483543 13690142 3540010..3540276 1 NC_018650.1 COG1734 DnaK suppressor protein; hypothetical protein 3540276 13690142 O3M_17305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771089.1 3540010 D 1134782 CDS YP_006771090.1 410483544 13690143 3540541..3540801 1 NC_018650.1 hypothetical protein 3540801 13690143 O3M_17310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771090.1 3540541 D 1134782 CDS YP_006771091.1 410483545 13690144 complement(3541030..3542115) 1 NC_018650.1 COG2055 Malate/L-lactate dehydrogenases; dehydrogenase 3542115 13690144 O3M_17315 Escherichia coli O104:H4 str. 2009EL-2050 dehydrogenase YP_006771091.1 3541030 R 1134782 CDS YP_006771092.1 410483546 13690145 complement(3542256..3543218) 1 NC_018650.1 COG0547 Anthranilate phosphoribosyltransferase; glycosyl transferase family protein 3543218 13690145 O3M_17320 Escherichia coli O104:H4 str. 2009EL-2050 glycosyl transferase family protein YP_006771092.1 3542256 R 1134782 CDS YP_006771093.1 410483547 13690146 complement(3543246..3545396) 1 NC_018650.1 COG1199 Rad3-related DNA helicases; ATP-dependent DNA helicase DinG 3545396 dinG 13690146 dinG Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent DNA helicase DinG YP_006771093.1 3543246 R 1134782 CDS YP_006771094.1 410483548 13690147 3545516..3545998 1 NC_018650.1 COG3236 Uncharacterized protein conserved in bacteria; hypothetical protein 3545998 13690147 O3M_17330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771094.1 3545516 D 1134782 CDS YP_006771095.1 410483549 13690148 complement(3546128..3546223) 1 NC_018650.1 hypothetical protein 3546223 13690148 O3M_17335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771095.1 3546128 R 1134782 CDS YP_006771096.1 410483550 13690149 complement(3546230..3547594) 1 NC_018650.1 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlE 3547594 13690149 O3M_17340 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent RNA helicase RhlE YP_006771096.1 3546230 R 1134782 CDS YP_006771097.1 410483551 13690150 3547823..3548494 1 NC_018650.1 COG1309 Transcriptional regulator; DNA-binding transcriptional regulator 3548494 13690150 O3M_17345 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771097.1 3547823 D 1134782 CDS YP_006771098.1 410483552 13690151 3548497..3549492 1 NC_018650.1 COG0845 Membrane-fusion protein; efflux pump membrane fusion protein 3549492 13690151 O3M_17350 Escherichia coli O104:H4 str. 2009EL-2050 efflux pump membrane fusion protein YP_006771098.1 3548497 D 1134782 CDS YP_006771099.1 410483553 13690152 3549485..3551221 1 NC_018650.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 3551221 13690152 O3M_17355 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006771099.1 3549485 D 1134782 CDS YP_006771100.1 410483554 13690153 3551214..3552347 1 NC_018650.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 3552347 13690153 O3M_17360 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter permease YP_006771100.1 3551214 D 1134782 CDS YP_006771101.1 410483555 13690154 3552358..3553464 1 NC_018650.1 COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 3553464 13690154 O3M_17365 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771101.1 3552358 D 1134782 CDS YP_006771102.1 410483556 13690155 complement(3553426..3553836) 1 NC_018650.1 COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; hypothetical protein 3553836 13690155 O3M_17370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771102.1 3553426 R 1134782 CDS YP_006771103.1 410483557 13690156 3553969..3554730 1 NC_018650.1 COG3568 Metal-dependent hydrolase; hypothetical protein 3554730 13690156 O3M_17375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771103.1 3553969 D 1134782 CDS YP_006771104.1 410483558 13690157 3554727..3555968 1 NC_018650.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; cardiolipin synthase 2 3555968 13690157 O3M_17380 Escherichia coli O104:H4 str. 2009EL-2050 cardiolipin synthase 2 YP_006771104.1 3554727 D 1134782 CDS YP_006771105.1 410483559 13690158 3555968..3556924 1 NC_018650.1 COG0392 Predicted integral membrane protein; hypothetical protein 3556924 13690158 O3M_17385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771105.1 3555968 D 1134782 CDS YP_006771106.1 410483560 13690159 complement(3556960..3557673) 1 NC_018650.1 COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein 3557673 13690159 O3M_17390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771106.1 3556960 R 1134782 CDS YP_006771107.1 410483561 13690160 complement(3557743..3558447) 1 NC_018650.1 COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein 3558447 13690160 O3M_17395 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771107.1 3557743 R 1134782 CDS YP_006771108.1 410483562 13690161 complement(3558592..3559296) 1 NC_018650.1 COG0670 Integral membrane protein, interacts with FtsH; inner membrane protein 3559296 13690161 O3M_17400 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771108.1 3558592 R 1134782 CDS YP_006771109.1 410483563 13690162 complement(3559433..3559885) 1 NC_018650.1 COG0314 Molybdopterin converting factor, large subunit; molybdopterin guanine dinucleotide biosynthesis protein MoaE 3559885 moaE 13690162 moaE Escherichia coli O104:H4 str. 2009EL-2050 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_006771109.1 3559433 R 1134782 CDS YP_006771110.1 410483564 13690163 complement(3559887..3560132) 1 NC_018650.1 COG1977 Molybdopterin converting factor, small subunit; molybdopterin synthase small subunit 3560132 moaD 13690163 moaD Escherichia coli O104:H4 str. 2009EL-2050 molybdopterin synthase small subunit YP_006771110.1 3559887 R 1134782 CDS YP_006771111.1 410483565 13690164 complement(3560125..3560610) 1 NC_018650.1 COG0315 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein MoaC 3560610 moaC 13690164 moaC Escherichia coli O104:H4 str. 2009EL-2050 molybdenum cofactor biosynthesis protein MoaC YP_006771111.1 3560125 R 1134782 CDS YP_006771112.1 410483566 13690165 complement(3560613..3561125) 1 NC_018650.1 COG0521 Molybdopterin biosynthesis enzymes; molybdenum cofactor biosynthesis protein B 3561125 13690165 O3M_17420 Escherichia coli O104:H4 str. 2009EL-2050 molybdenum cofactor biosynthesis protein B YP_006771112.1 3560613 R 1134782 CDS YP_006771113.1 410483567 13690166 complement(3561147..3562136) 1 NC_018650.1 COG2896 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein A 3562136 moaA 13690166 moaA Escherichia coli O104:H4 str. 2009EL-2050 molybdenum cofactor biosynthesis protein A YP_006771113.1 3561147 R 1134782 CDS YP_006771114.1 410483568 13690167 3562135..3562290 1 NC_018650.1 hypothetical protein 3562290 13690167 O3M_17430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771114.1 3562135 D 1134782 CDS YP_006771115.1 410483569 13690168 3562533..3563441 1 NC_018650.1 COG0391 Uncharacterized conserved protein; transferase with NAD(P)-binding Rossmann-fold domain 3563441 13690168 O3M_17435 Escherichia coli O104:H4 str. 2009EL-2050 transferase with NAD(P)-binding Rossmann-fold domain YP_006771115.1 3562533 D 1134782 CDS YP_006771116.1 410483570 13690169 complement(3563633..3565654) 1 NC_018650.1 COG0556 Helicase subunit of the DNA excision repair complex; excinuclease ABC subunit B 3565654 13690169 O3M_17440 Escherichia coli O104:H4 str. 2009EL-2050 excinuclease ABC subunit B YP_006771116.1 3563633 R 1134782 CDS YP_006771117.1 410483571 13690170 complement(3566240..3566917) 1 NC_018650.1 COG0132 Dethiobiotin synthetase; dithiobiotin synthetase 3566917 bioD 13690170 bioD Escherichia coli O104:H4 str. 2009EL-2050 dithiobiotin synthetase YP_006771117.1 3566240 R 1134782 CDS YP_006771118.1 410483572 13690171 complement(3566910..3567665) 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; biotin biosynthesis protein BioC 3567665 13690171 O3M_17450 Escherichia coli O104:H4 str. 2009EL-2050 biotin biosynthesis protein BioC YP_006771118.1 3566910 R 1134782 CDS YP_006771119.1 410483573 13690172 complement(3567652..3568806) 1 NC_018650.1 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase 3568806 13690172 O3M_17455 Escherichia coli O104:H4 str. 2009EL-2050 8-amino-7-oxononanoate synthase YP_006771119.1 3567652 R 1134782 CDS YP_006771120.1 410483574 13690173 complement(3568803..3569843) 1 NC_018650.1 COG0502 Biotin synthase and related enzymes; biotin synthase 3569843 13690173 O3M_17460 Escherichia coli O104:H4 str. 2009EL-2050 biotin synthase YP_006771120.1 3568803 R 1134782 CDS YP_006771121.1 410483575 13690174 3569930..3571219 1 NC_018650.1 COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 3571219 13690174 O3M_17465 Escherichia coli O104:H4 str. 2009EL-2050 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_006771121.1 3569930 D 1134782 CDS YP_006771122.1 410483576 13690175 3571278..3571754 1 NC_018650.1 COG1881 Phospholipid-binding protein; kinase inhibitor protein 3571754 13690175 O3M_17470 Escherichia coli O104:H4 str. 2009EL-2050 kinase inhibitor protein YP_006771122.1 3571278 D 1134782 CDS YP_006771123.1 410483577 13690176 3572500..3573831 1 NC_018650.1 COG2199 FOG: GGDEF domain; hypothetical protein 3573831 13690176 O3M_17475 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771123.1 3572500 D 1134782 CDS YP_006771124.1 410483578 13690177 complement(3573905..3574489) 1 NC_018650.1 Qin prophage; tail fiber chaperone 3574489 13690177 O3M_17480 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber chaperone YP_006771124.1 3573905 R 1134782 CDS YP_006771125.1 410483579 13690178 complement(3574489..3576198) 1 NC_018650.1 phage tail fiber protein 3576198 13690178 O3M_17485 Escherichia coli O104:H4 str. 2009EL-2050 phage tail fiber protein YP_006771125.1 3574489 R 1134782 CDS YP_006771126.1 410483580 13690179 3576176..3577066 1 NC_018650.1 hypothetical protein 3577066 13690179 O3M_17490 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771126.1 3576176 D 1134782 CDS YP_006771127.1 410483581 13690180 3577454..3577627 1 NC_018650.1 hypothetical protein 3577627 13690180 O3M_17495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771127.1 3577454 D 1134782 CDS YP_006771128.1 410483582 13690181 complement(3577628..3578227) 1 NC_018650.1 Lom-like outer membrane protein of phage origin 3578227 13690181 O3M_17500 Escherichia coli O104:H4 str. 2009EL-2050 Lom-like outer membrane protein of phage origin YP_006771128.1 3577628 R 1134782 CDS YP_006771129.1 410483583 13690182 complement(3578298..3581795) 1 NC_018650.1 COG4733 Phage-related protein, tail component; Host specificity protein J of prophage 3581795 13690182 O3M_17505 Escherichia coli O104:H4 str. 2009EL-2050 Host specificity protein J of prophage YP_006771129.1 3578298 R 1134782 CDS YP_006771130.1 410483584 13690183 complement(3581856..3582527) 1 NC_018650.1 COG4723 Phage-related protein, tail component; Tail assembly protein I 3582527 13690183 O3M_17510 Escherichia coli O104:H4 str. 2009EL-2050 Tail assembly protein I YP_006771130.1 3581856 R 1134782 CDS YP_006771131.1 410483585 13690184 complement(3582425..3583168) 1 NC_018650.1 COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; tail fiber component K of prophage 3583168 13690184 O3M_17515 Escherichia coli O104:H4 str. 2009EL-2050 tail fiber component K of prophage YP_006771131.1 3582425 R 1134782 CDS YP_006771132.1 410483586 13690185 complement(3583174..3583872) 1 NC_018650.1 COG4672 Phage-related protein; minor tail protein L 3583872 13690185 O3M_17520 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein L YP_006771132.1 3583174 R 1134782 CDS YP_006771133.1 410483587 13690186 complement(3583872..3584201) 1 NC_018650.1 COG4718 Phage-related protein; minor tail protein M 3584201 13690186 O3M_17525 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein M YP_006771133.1 3583872 R 1134782 CDS YP_006771134.1 410483588 13690187 complement(3584198..3586759) 1 NC_018650.1 minor tail protein H 3586759 13690187 O3M_17530 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein H YP_006771134.1 3584198 R 1134782 CDS YP_006771135.1 410483589 13690188 complement(3586752..3587186) 1 NC_018650.1 minor tail protein 3587186 13690188 O3M_17535 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein YP_006771135.1 3586752 R 1134782 CDS YP_006771136.1 410483590 13690189 complement(3587168..3587590) 1 NC_018650.1 minor tail protein G 3587590 13690189 O3M_17540 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein G YP_006771136.1 3587168 R 1134782 CDS YP_006771137.1 410483591 13690190 complement(3587606..3588346) 1 NC_018650.1 COG5492 Bacterial surface proteins containing Ig-like domains; major tail protein V 3588346 13690190 O3M_17545 Escherichia coli O104:H4 str. 2009EL-2050 major tail protein V YP_006771137.1 3587606 R 1134782 CDS YP_006771138.1 410483592 13690191 complement(3588354..3588749) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; minor tail protein U 3588749 13690191 O3M_17550 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein U YP_006771138.1 3588354 R 1134782 CDS YP_006771139.1 410483593 13690192 complement(3588746..3589324) 1 NC_018650.1 minor tail protein Z (GpZ) 3589324 13690192 O3M_17555 Escherichia coli O104:H4 str. 2009EL-2050 minor tail protein Z (GpZ) YP_006771139.1 3588746 R 1134782 CDS YP_006771140.1 410483594 13690193 complement(3589336..3589689) 1 NC_018650.1 Tail attachment protein (Minor capsid protein FII) from bacteriophage origin 3589689 13690193 O3M_17560 Escherichia coli O104:H4 str. 2009EL-2050 Tail attachment protein (Minor capsid protein FII) from bacteriophage origin YP_006771140.1 3589336 R 1134782 CDS YP_006771141.1 410483595 13690194 complement(3589701..3590096) 1 NC_018650.1 phage DNA packaging protein 3590096 13690194 O3M_17565 Escherichia coli O104:H4 str. 2009EL-2050 phage DNA packaging protein YP_006771141.1 3589701 R 1134782 CDS YP_006771142.1 410483596 13690195 complement(3590138..3591163) 1 NC_018650.1 major head coat protein from bacteriophage origin 3591163 13690195 O3M_17570 Escherichia coli O104:H4 str. 2009EL-2050 major head coat protein from bacteriophage origin YP_006771142.1 3590138 R 1134782 CDS YP_006771143.1 410483597 13690196 complement(3591219..3591551) 1 NC_018650.1 Head decoration protein from bacteriophage origin 3591551 13690196 O3M_17575 Escherichia coli O104:H4 str. 2009EL-2050 Head decoration protein from bacteriophage origin YP_006771143.1 3591219 R 1134782 CDS YP_006771144.1 410483598 13690197 complement(3591561..3592880) 1 NC_018650.1 COG0616 Periplasmic serine proteases (ClpP class); minor capsid protein C from bacteriophage origin 3592880 13690197 O3M_17580 Escherichia coli O104:H4 str. 2009EL-2050 minor capsid protein C from bacteriophage origin YP_006771144.1 3591561 R 1134782 CDS YP_006771145.1 410483599 13690198 complement(3592861..3594462) 1 NC_018650.1 COG5511 Bacteriophage capsid protein; phage portal protein, lambda family 3594462 13690198 O3M_17585 Escherichia coli O104:H4 str. 2009EL-2050 phage portal protein, lambda family YP_006771145.1 3592861 R 1134782 CDS YP_006771146.1 410483600 13690199 complement(3594459..3594665) 1 NC_018650.1 Lambda prophage-derived head-to-tail joining protein W 3594665 13690199 O3M_17590 Escherichia coli O104:H4 str. 2009EL-2050 Lambda prophage-derived head-to-tail joining protein W YP_006771146.1 3594459 R 1134782 CDS YP_006771147.1 410483601 13690200 complement(3594662..3594880) 1 NC_018650.1 bacteriophage tail assembly protein 3594880 13690200 O3M_17595 Escherichia coli O104:H4 str. 2009EL-2050 bacteriophage tail assembly protein YP_006771147.1 3594662 R 1134782 CDS YP_006771148.1 410483602 13690201 complement(3594925..3596586) 1 NC_018650.1 COG5525 Bacteriophage tail assembly protein; Terminase large subunit from bacteriophage origin 3596586 13690201 O3M_17600 Escherichia coli O104:H4 str. 2009EL-2050 Terminase large subunit from bacteriophage origin YP_006771148.1 3594925 R 1134782 CDS YP_006771149.1 410483603 13690202 complement(3596561..3597106) 1 NC_018650.1 COG4220 Phage DNA packaging protein, Nu1 subunit of terminase; terminase small subunit 3597106 13690202 O3M_17605 Escherichia coli O104:H4 str. 2009EL-2050 terminase small subunit YP_006771149.1 3596561 R 1134782 CDS YP_006771150.1 410483604 13690203 3597495..3597728 1 NC_018650.1 Qin prophage 3597728 13690203 O3M_17610 Escherichia coli O104:H4 str. 2009EL-2050 Qin prophage YP_006771150.1 3597495 D 1134782 CDS YP_006771151.1 410483605 13690204 3597785..3598195 1 NC_018650.1 COG5562 Phage envelope protein; phage protein 3598195 13690204 O3M_17615 Escherichia coli O104:H4 str. 2009EL-2050 phage protein YP_006771151.1 3597785 D 1134782 CDS YP_006771152.1 410483606 13690205 complement(3598545..3599066) 1 NC_018650.1 phage protein 3599066 13690205 O3M_17620 Escherichia coli O104:H4 str. 2009EL-2050 phage protein YP_006771152.1 3598545 R 1134782 CDS YP_006771153.1 410483607 13690206 complement(3599271..3599708) 1 NC_018650.1 bacteriophage lysis protein 3599708 13690206 O3M_17625 Escherichia coli O104:H4 str. 2009EL-2050 bacteriophage lysis protein YP_006771153.1 3599271 R 1134782 CDS YP_006771154.1 410483608 13690207 complement(3599705..3600202) 1 NC_018650.1 DLP12 prophage; COG3772 Phage-related lysozyme (muraminidase); lysozyme 3600202 13690207 O3M_17630 Escherichia coli O104:H4 str. 2009EL-2050 lysozyme YP_006771154.1 3599705 R 1134782 CDS YP_006771155.1 410483609 13690208 complement(3600202..3600417) 1 NC_018650.1 phage lysis protein 3600417 13690208 O3M_17635 Escherichia coli O104:H4 str. 2009EL-2050 phage lysis protein YP_006771155.1 3600202 R 1134782 CDS YP_006771156.1 410483610 13690209 3601006..3602088 1 NC_018650.1 COG3203 Outer membrane protein (porin); outer membrane porin, DLP12 prophage 3602088 13690209 O3M_17640 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane porin, DLP12 prophage YP_006771156.1 3601006 D 1134782 CDS YP_006771157.1 410483611 13690210 complement(3602277..3602660) 1 NC_018650.1 antitermination protein Q 3602660 13690210 O3M_17645 Escherichia coli O104:H4 str. 2009EL-2050 antitermination protein Q YP_006771157.1 3602277 R 1134782 CDS YP_006771158.1 410483612 13690211 complement(3602746..3602886) 1 NC_018650.1 hypothetical protein 3602886 13690211 O3M_17650 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771158.1 3602746 R 1134782 CDS YP_006771159.1 410483613 13690212 complement(3602883..3603110) 1 NC_018650.1 COG4570 Holliday junction resolvase; endodeoxyribonuclease RUS 3603110 13690212 O3M_17655 Escherichia coli O104:H4 str. 2009EL-2050 endodeoxyribonuclease RUS YP_006771159.1 3602883 R 1134782 CDS YP_006771160.1 410483614 13690213 complement(3603241..3603531) 1 NC_018650.1 hypothetical protein 3603531 13690213 O3M_17660 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771160.1 3603241 R 1134782 CDS YP_006771161.1 410483615 13690214 complement(3603524..3603694) 1 NC_018650.1 prophage protein NinE 3603694 13690214 O3M_17665 Escherichia coli O104:H4 str. 2009EL-2050 prophage protein NinE YP_006771161.1 3603524 R 1134782 CDS YP_006771162.1 410483616 13690215 complement(3603694..3604149) 1 NC_018650.1 hypothetical protein 3604149 13690215 O3M_17670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771162.1 3603694 R 1134782 CDS YP_006771163.1 410483617 13690216 complement(3604344..3604853) 1 NC_018650.1 hypothetical protein 3604853 13690216 O3M_17675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771163.1 3604344 R 1134782 CDS YP_006771164.1 410483618 13690217 complement(3605172..3605411) 1 NC_018650.1 antirepressor protein 3605411 13690217 O3M_17680 Escherichia coli O104:H4 str. 2009EL-2050 antirepressor protein YP_006771164.1 3605172 R 1134782 CDS YP_006771165.1 410483619 13690218 complement(3605523..3606317) 1 NC_018650.1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; phage recombinase 3606317 13690218 O3M_17685 Escherichia coli O104:H4 str. 2009EL-2050 phage recombinase YP_006771165.1 3605523 R 1134782 CDS YP_006771166.1 410483620 13690219 complement(3606274..3606516) 1 NC_018650.1 COG2076 Membrane transporters of cations and cationic drugs; multidrug efflux protein 3606516 emrE 13690219 emrE Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux protein YP_006771166.1 3606274 R 1134782 CDS YP_006771167.1 410483621 13690220 complement(3606563..3606865) 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Ren protein from phage origin 3606865 13690220 O3M_17695 Escherichia coli O104:H4 str. 2009EL-2050 Ren protein from phage origin YP_006771167.1 3606563 R 1134782 CDS YP_006771168.1 410483622 13690221 complement(3606862..3607563) 1 NC_018650.1 replication protein P of bacteriophage 3607563 13690221 O3M_17700 Escherichia coli O104:H4 str. 2009EL-2050 replication protein P of bacteriophage YP_006771168.1 3606862 R 1134782 CDS YP_006771169.1 410483623 13690222 complement(3607560..3608489) 1 NC_018650.1 Replication protein O frm phage origin 3608489 13690222 O3M_17705 Escherichia coli O104:H4 str. 2009EL-2050 Replication protein O frm phage origin YP_006771169.1 3607560 R 1134782 CDS YP_006771170.1 410483624 13690223 complement(3608576..3609115) 1 NC_018650.1 coiled-coil; Regulatory protein CII (modular protein) from bacteriophage origin 3609115 13690223 O3M_17710 Escherichia coli O104:H4 str. 2009EL-2050 Regulatory protein CII (modular protein) from bacteriophage origin YP_006771170.1 3608576 R 1134782 CDS YP_006771171.1 410483625 13690224 complement(3609185..3609415) 1 NC_018650.1 phage regulatory protein Cro 3609415 13690224 O3M_17715 Escherichia coli O104:H4 str. 2009EL-2050 phage regulatory protein Cro YP_006771171.1 3609185 R 1134782 CDS YP_006771172.1 410483626 13690225 3609521..3610210 1 NC_018650.1 COG2932 Predicted transcriptional regulator; phage repressor protein CI 3610210 13690225 O3M_17720 Escherichia coli O104:H4 str. 2009EL-2050 phage repressor protein CI YP_006771172.1 3609521 D 1134782 CDS YP_006771173.1 410483627 13690226 3610808..3611014 1 NC_018650.1 prophage Kil protein 3611014 13690226 O3M_17725 Escherichia coli O104:H4 str. 2009EL-2050 prophage Kil protein YP_006771173.1 3610808 D 1134782 CDS YP_006771174.1 410483628 13690227 3611090..3611386 1 NC_018650.1 host-nuclease inhibitor protein Gam of bacteriophage 3611386 13690227 O3M_17730 Escherichia coli O104:H4 str. 2009EL-2050 host-nuclease inhibitor protein Gam of bacteriophage YP_006771174.1 3611090 D 1134782 CDS YP_006771175.1 410483629 13690228 3611392..3612177 1 NC_018650.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Bet protein 3612177 13690228 O3M_17735 Escherichia coli O104:H4 str. 2009EL-2050 Bet protein YP_006771175.1 3611392 D 1134782 CDS YP_006771176.1 410483630 13690229 3612174..3612854 1 NC_018650.1 exonuclease from phage origin 3612854 13690229 O3M_17740 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease from phage origin YP_006771176.1 3612174 D 1134782 CDS YP_006771177.1 410483631 13690230 3612845..3613033 1 NC_018650.1 hypothetical protein 3613033 13690230 O3M_17745 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771177.1 3612845 D 1134782 CDS YP_006771178.1 410483632 13690231 3613006..3613197 1 NC_018650.1 phage protein 3613197 13690231 O3M_17750 Escherichia coli O104:H4 str. 2009EL-2050 phage protein YP_006771178.1 3613006 D 1134782 CDS YP_006771179.1 410483633 13690232 3613194..3613277 1 NC_018650.1 hypothetical protein 3613277 13690232 O3M_17755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771179.1 3613194 D 1134782 CDS YP_006771180.1 410483634 13690233 3613208..3613489 1 NC_018650.1 hypothetical protein 3613489 13690233 O3M_17760 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771180.1 3613208 D 1134782 CDS YP_006771181.1 410483635 13690234 3613588..3613809 1 NC_018650.1 COG1734 DnaK suppressor protein; hypothetical protein 3613809 13690234 O3M_17765 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771181.1 3613588 D 1134782 CDS YP_006771182.1 410483636 13690235 complement(3614020..3614550) 1 NC_018650.1 hypothetical protein 3614550 13690235 O3M_17770 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771182.1 3614020 R 1134782 CDS YP_006771183.1 410483637 13690236 3614865..3615032 1 NC_018650.1 hypothetical protein 3615032 13690236 O3M_17775 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771183.1 3614865 D 1134782 CDS YP_006771184.1 410483638 13690237 3615072..3615290 1 NC_018650.1 excisionase 3615290 13690237 O3M_17780 Escherichia coli O104:H4 str. 2009EL-2050 excisionase YP_006771184.1 3615072 D 1134782 CDS YP_006771185.1 410483639 13690238 3615268..3616338 1 NC_018650.1 COG0582 Integrase; Integrase from phage 3616338 13690238 O3M_17785 Escherichia coli O104:H4 str. 2009EL-2050 Integrase from phage YP_006771185.1 3615268 D 1134782 CDS YP_006771186.1 410483640 13690239 3616473..3617756 1 NC_018650.1 COG4677 Pectin methylesterase; acyl-CoA thioesterase 3617756 13690239 O3M_17790 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA thioesterase YP_006771186.1 3616473 D 1134782 CDS YP_006771187.1 410483641 13690240 complement(3617990..3620251) 1 NC_018650.1 COG1048 Aconitase A; hydratase 3620251 13690240 O3M_17795 Escherichia coli O104:H4 str. 2009EL-2050 hydratase YP_006771187.1 3617990 R 1134782 CDS YP_006771188.1 410483642 13690241 complement(3620434..3621867) 1 NC_018650.1 COG0471 Di- and tricarboxylate transporters; transporter 3621867 13690241 O3M_17800 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771188.1 3620434 R 1134782 CDS YP_006771189.1 410483643 13690242 complement(3621943..3622995) 1 NC_018650.1 COG2828 Uncharacterized protein conserved in bacteria; hypothetical protein 3622995 13690242 O3M_17805 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771189.1 3621943 R 1134782 CDS YP_006771190.1 410483644 13690243 3623179..3624132 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 3624132 13690243 O3M_17810 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771190.1 3623179 D 1134782 CDS YP_006771191.1 410483645 13690244 complement(3624173..3625168) 1 NC_018650.1 COG2706 3-carboxymuconate cyclase; 6-phosphogluconolactonase 3625168 13690244 O3M_17815 Escherichia coli O104:H4 str. 2009EL-2050 6-phosphogluconolactonase YP_006771191.1 3624173 R 1134782 CDS YP_006771192.1 410483646 13690245 3625323..3626141 1 NC_018650.1 COG0561 Predicted hydrolases of the HAD superfamily; pyridoxal phosphate (PLP) phosphatase 3626141 13690245 O3M_17820 Escherichia coli O104:H4 str. 2009EL-2050 pyridoxal phosphate (PLP) phosphatase YP_006771192.1 3625323 D 1134782 CDS YP_006771193.1 410483647 13690246 complement(3626142..3627200) 1 NC_018650.1 COG4148 ABC-type molybdate transport system, ATPase component; molybdate transporter ATP-binding protein 3627200 modC 13690246 modC Escherichia coli O104:H4 str. 2009EL-2050 molybdate transporter ATP-binding protein YP_006771193.1 3626142 R 1134782 CDS YP_006771194.1 410483648 13690247 complement(3627203..3627892) 1 NC_018650.1 COG4149 ABC-type molybdate transport system, permease component; molybdate ABC transporter permease 3627892 modB 13690247 modB Escherichia coli O104:H4 str. 2009EL-2050 molybdate ABC transporter permease YP_006771194.1 3627203 R 1134782 CDS YP_006771195.1 410483649 13690248 complement(3627892..3628665) 1 NC_018650.1 COG0725 ABC-type molybdate transport system, periplasmic component; molybdate transporter periplasmic protein 3628665 modA 13690248 modA Escherichia coli O104:H4 str. 2009EL-2050 molybdate transporter periplasmic protein YP_006771195.1 3627892 R 1134782 CDS YP_006771196.1 410483650 13690249 complement(3628832..3628981) 1 NC_018650.1 hypothetical protein 3628981 13690249 O3M_17840 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771196.1 3628832 R 1134782 CDS YP_006771197.1 410483651 13690250 3629110..3629898 1 NC_018650.1 COG2005 N-terminal domain of molybdenum-binding protein; DNA-binding transcriptional regulator ModE 3629898 13690250 O3M_17845 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator ModE YP_006771197.1 3629110 D 1134782 CDS YP_006771198.1 410483652 13690251 3629966..3631438 1 NC_018650.1 COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; molybdenum transport ATP-binding protein ModF 3631438 13690251 O3M_17850 Escherichia coli O104:H4 str. 2009EL-2050 molybdenum transport ATP-binding protein ModF YP_006771198.1 3629966 D 1134782 CDS YP_006771199.1 410483653 13690252 3631699..3632715 1 NC_018650.1 COG1087 UDP-glucose 4-epimerase; UDP-galactose-4-epimerase 3632715 13690252 O3M_17855 Escherichia coli O104:H4 str. 2009EL-2050 UDP-galactose-4-epimerase YP_006771199.1 3631699 D 1134782 CDS YP_006771200.1 410483654 13690253 3632725..3633771 1 NC_018650.1 COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 3633771 13690253 O3M_17860 Escherichia coli O104:H4 str. 2009EL-2050 galactose-1-phosphate uridylyltransferase YP_006771200.1 3632725 D 1134782 CDS YP_006771201.1 410483655 13690254 3633775..3634923 1 NC_018650.1 COG0153 Galactokinase; galactokinase 3634923 13690254 O3M_17865 Escherichia coli O104:H4 str. 2009EL-2050 galactokinase YP_006771201.1 3633775 D 1134782 CDS YP_006771202.1 410483656 13690255 3634917..3635957 1 NC_018650.1 COG2017 Galactose mutarotase and related enzymes; galactose-1-epimerase 3635957 galM 13690255 galM Escherichia coli O104:H4 str. 2009EL-2050 galactose-1-epimerase YP_006771202.1 3634917 D 1134782 CDS YP_006771203.1 410483657 13690256 3636162..3636914 1 NC_018650.1 COG0588 Phosphoglycerate mutase 1; phosphoglyceromutase 3636914 gpmA 13690256 gpmA Escherichia coli O104:H4 str. 2009EL-2050 phosphoglyceromutase YP_006771203.1 3636162 D 1134782 CDS YP_006771204.1 410483658 13690257 complement(3637072..3638124) 1 NC_018650.1 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase 3638124 13690257 O3M_17880 Escherichia coli O104:H4 str. 2009EL-2050 phospho-2-dehydro-3-deoxyheptonate aldolase YP_006771204.1 3637072 R 1134782 CDS YP_006771205.1 410483659 13690258 3638440..3638820 1 NC_018650.1 hypothetical protein 3638820 13690258 O3M_17885 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771205.1 3638440 D 1134782 CDS YP_006771206.1 410483660 13690259 3638934..3639875 1 NC_018650.1 COG1230 Co/Zn/Cd efflux system component; zinc transporter ZitB 3639875 13690259 O3M_17890 Escherichia coli O104:H4 str. 2009EL-2050 zinc transporter ZitB YP_006771206.1 3638934 D 1134782 CDS YP_006771207.1 410483661 13690260 complement(3639872..3640591) 1 NC_018650.1 COG3201 Nicotinamide mononucleotide transporter; nicotinamide riboside transporter PnuC 3640591 13690260 O3M_17895 Escherichia coli O104:H4 str. 2009EL-2050 nicotinamide riboside transporter PnuC YP_006771207.1 3639872 R 1134782 CDS YP_006771208.1 410483662 13690261 complement(3640629..3641672) 1 NC_018650.1 COG0379 Quinolinate synthase; quinolinate synthetase 3641672 13690261 O3M_17900 Escherichia coli O104:H4 str. 2009EL-2050 quinolinate synthetase YP_006771208.1 3640629 R 1134782 CDS YP_006771209.1 410483663 13690269 complement(3643141..3643932) 1 NC_018650.1 COG1729 Uncharacterized protein conserved in bacteria; tol-pal system protein YbgF 3643932 13690269 O3M_17905 Escherichia coli O104:H4 str. 2009EL-2050 tol-pal system protein YbgF YP_006771209.1 3643141 R 1134782 CDS YP_006771210.1 410483664 13690270 complement(3643942..3644463) 1 NC_018650.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated outer membrane lipoprotein 3644463 13690270 O3M_17910 Escherichia coli O104:H4 str. 2009EL-2050 peptidoglycan-associated outer membrane lipoprotein YP_006771210.1 3643942 R 1134782 CDS YP_006771211.1 410483665 13690271 complement(3644498..3645790) 1 NC_018650.1 COG0823 Periplasmic component of the Tol biopolymer transport system; translocation protein TolB 3645790 tolB 13690271 tolB Escherichia coli O104:H4 str. 2009EL-2050 translocation protein TolB YP_006771211.1 3644498 R 1134782 CDS YP_006771212.1 410483666 13690272 complement(3645923..3647188) 1 NC_018650.1 COG3064 Membrane protein involved in colicin uptake; cell envelope integrity inner membrane protein TolA 3647188 tolA 13690272 tolA Escherichia coli O104:H4 str. 2009EL-2050 cell envelope integrity inner membrane protein TolA YP_006771212.1 3645923 R 1134782 CDS YP_006771213.1 410483667 13690273 complement(3647253..3647681) 1 NC_018650.1 COG0848 Biopolymer transport protein; colicin uptake protein TolR 3647681 13690273 O3M_17925 Escherichia coli O104:H4 str. 2009EL-2050 colicin uptake protein TolR YP_006771213.1 3647253 R 1134782 CDS YP_006771214.1 410483668 13690274 complement(3647685..3648377) 1 NC_018650.1 COG0811 Biopolymer transport proteins; colicin uptake protein TolQ 3648377 13690274 O3M_17930 Escherichia coli O104:H4 str. 2009EL-2050 colicin uptake protein TolQ YP_006771214.1 3647685 R 1134782 CDS YP_006771215.1 410483669 13690275 complement(3648374..3648778) 1 NC_018650.1 COG0824 Predicted thioesterase; acyl-CoA thioesterase YbgC 3648778 13690275 O3M_17935 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA thioesterase YbgC YP_006771215.1 3648374 R 1134782 CDS YP_006771216.1 410483670 13690276 complement(3648928..3649221) 1 NC_018650.1 COG3790 Predicted membrane protein; hypothetical protein 3649221 13690276 O3M_17940 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771216.1 3648928 R 1134782 CDS YP_006771217.1 410483671 13690277 complement(3649221..3649334) 1 NC_018650.1 COG4890 Predicted outer membrane lipoprotein; cyd operon protein YbgT 3649334 13690277 O3M_17945 Escherichia coli O104:H4 str. 2009EL-2050 cyd operon protein YbgT YP_006771217.1 3649221 R 1134782 CDS YP_006771218.1 410483672 13690278 complement(3649349..3650488) 1 NC_018650.1 COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome d ubiquinol oxidase subunit 2 3650488 13690278 O3M_17950 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome d ubiquinol oxidase subunit 2 YP_006771218.1 3649349 R 1134782 CDS YP_006771219.1 410483673 13690279 complement(3650504..3652072) 1 NC_018650.1 COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome d terminal oxidase subunit 1 3652072 13690279 O3M_17955 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome d terminal oxidase subunit 1 YP_006771219.1 3650504 R 1134782 CDS YP_006771220.1 410483674 13690280 complement(3652667..3652894) 1 NC_018650.1 hypothetical protein 3652894 13690280 O3M_17960 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771220.1 3652667 R 1134782 CDS YP_006771221.1 410483675 13690281 complement(3652919..3655552) 1 NC_018650.1 COG0383 Alpha-mannosidase; alpha-mannosidase 3655552 13690281 O3M_17965 Escherichia coli O104:H4 str. 2009EL-2050 alpha-mannosidase YP_006771221.1 3652919 R 1134782 CDS YP_006771222.1 410483676 13690282 complement(3655570..3657546) 1 NC_018650.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 3657546 13690282 O3M_17970 Escherichia coli O104:H4 str. 2009EL-2050 PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC YP_006771222.1 3655570 R 1134782 CDS YP_006771223.1 410483677 13690283 3657655..3658377 1 NC_018650.1 COG2188 Transcriptional regulators; DNA-binding transcriptional repressor MngR 3658377 13690283 O3M_17975 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor MngR YP_006771223.1 3657655 D 1134782 CDS YP_006771224.1 410483678 13690284 complement(3658481..3659350) 1 NC_018650.1 COG0074 Succinyl-CoA synthetase, alpha subunit; succinyl-CoA synthetase subunit alpha 3659350 13690284 O3M_17980 Escherichia coli O104:H4 str. 2009EL-2050 succinyl-CoA synthetase subunit alpha YP_006771224.1 3658481 R 1134782 CDS YP_006771225.1 410483679 13690285 complement(3659350..3660516) 1 NC_018650.1 COG0045 Succinyl-CoA synthetase, beta subunit; succinyl-CoA synthetase subunit beta 3660516 sucC 13690285 sucC Escherichia coli O104:H4 str. 2009EL-2050 succinyl-CoA synthetase subunit beta YP_006771225.1 3659350 R 1134782 CDS YP_006771226.1 410483680 13690286 complement(3660610..3661827) 1 NC_018650.1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; dihydrolipoamide succinyltransferase 3661827 13690286 O3M_17990 Escherichia coli O104:H4 str. 2009EL-2050 dihydrolipoamide succinyltransferase YP_006771226.1 3660610 R 1134782 CDS YP_006771227.1 410483681 13690287 complement(3661842..3664643) 1 NC_018650.1 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; 2-oxoglutarate dehydrogenase E1 component 3664643 sucA 13690287 sucA Escherichia coli O104:H4 str. 2009EL-2050 2-oxoglutarate dehydrogenase E1 component YP_006771227.1 3661842 R 1134782 CDS YP_006771228.1 410483682 13690288 complement(3664844..3665560) 1 NC_018650.1 COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; succinate dehydrogenase iron-sulfur subunit 3665560 sdhB 13690288 sdhB Escherichia coli O104:H4 str. 2009EL-2050 succinate dehydrogenase iron-sulfur subunit YP_006771228.1 3664844 R 1134782 CDS YP_006771229.1 410483683 13690289 complement(3665576..3667342) 1 NC_018650.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; succinate dehydrogenase flavoprotein subunit 3667342 sdhA 13690289 sdhA Escherichia coli O104:H4 str. 2009EL-2050 succinate dehydrogenase flavoprotein subunit YP_006771229.1 3665576 R 1134782 CDS YP_006771230.1 410483684 13690290 complement(3667342..3667689) 1 NC_018650.1 COG2142 Succinate dehydrogenase, hydrophobic anchor subunit; succinate dehydrogenase cytochrome b556 small membrane subunit 3667689 sdhD 13690290 sdhD Escherichia coli O104:H4 str. 2009EL-2050 succinate dehydrogenase cytochrome b556 small membrane subunit YP_006771230.1 3667342 R 1134782 CDS YP_006771231.1 410483685 13690291 complement(3667683..3668072) 1 NC_018650.1 COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; succinate dehydrogenase cytochrome b556 large membrane subunit 3668072 sdhC 13690291 sdhC Escherichia coli O104:H4 str. 2009EL-2050 succinate dehydrogenase cytochrome b556 large membrane subunit YP_006771231.1 3667683 R 1134782 CDS YP_006771232.1 410483686 13690292 complement(3668608..3668793) 1 NC_018650.1 hypothetical protein 3668793 13690292 O3M_18020 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771232.1 3668608 R 1134782 CDS YP_006771233.1 410483687 13690293 3668781..3670064 1 NC_018650.1 COG0372 Citrate synthase; type II citrate synthase 3670064 gltA 13690293 gltA Escherichia coli O104:H4 str. 2009EL-2050 type II citrate synthase YP_006771233.1 3668781 D 1134782 CDS YP_006771234.1 410483688 13690294 3670454..3671020 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like protein 3671020 13690294 O3M_18030 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like protein YP_006771234.1 3670454 D 1134782 CDS YP_006771235.1 410483689 13690295 3671080..3671328 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; fimbrial biogenesis outer membrane usher protein 3671328 13690295 O3M_18035 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial biogenesis outer membrane usher protein YP_006771235.1 3671080 D 1134782 CDS YP_006771236.1 410483690 13690296 3671357..3671632 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 3671632 13690296 O3M_18040 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006771236.1 3671357 D 1134782 CDS YP_006771237.1 410483691 13690297 3671551..3672054 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 3672054 13690297 O3M_18045 Escherichia coli O104:H4 str. 2009EL-2050 transposase InsB IS1 YP_006771237.1 3671551 D 1134782 CDS YP_006771238.1 410483692 13690298 3672089..3672739 1 NC_018650.1 hypothetical protein 3672739 13690298 O3M_18050 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771238.1 3672089 D 1134782 CDS YP_006771239.1 410483693 13690299 3672891..3673937 1 NC_018650.1 COG3180 Putative ammonia monooxygenase; transporter 3673937 13690299 O3M_18055 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771239.1 3672891 D 1134782 CDS YP_006771240.1 410483694 13690300 complement(3673934..3674725) 1 NC_018650.1 COG0266 Formamidopyrimidine-DNA glycosylase; endonuclease VIII 3674725 13690300 O3M_18060 Escherichia coli O104:H4 str. 2009EL-2050 endonuclease VIII YP_006771240.1 3673934 R 1134782 CDS YP_006771241.1 410483695 13690301 complement(3674761..3675495) 1 NC_018650.1 COG1540 Uncharacterized proteins, homologs of lactam utilization protein B; LamB/YcsF family protein 3675495 13690301 O3M_18065 Escherichia coli O104:H4 str. 2009EL-2050 LamB/YcsF family protein YP_006771241.1 3674761 R 1134782 CDS YP_006771242.1 410483696 13690302 complement(3675485..3676417) 1 NC_018650.1 COG1984 Allophanate hydrolase subunit 2; hydrolase subunit 3676417 13690302 O3M_18070 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase subunit YP_006771242.1 3675485 R 1134782 CDS YP_006771243.1 410483697 13690303 complement(3676411..3677067) 1 NC_018650.1 COG2049 Allophanate hydrolase subunit 1; carboxylase 3677067 13690303 O3M_18075 Escherichia coli O104:H4 str. 2009EL-2050 carboxylase YP_006771243.1 3676411 R 1134782 CDS YP_006771244.1 410483698 13690304 complement(3677090..3677833) 1 NC_018650.1 COG0327 Uncharacterized conserved protein; metal-binding protein 3677833 13690304 O3M_18080 Escherichia coli O104:H4 str. 2009EL-2050 metal-binding protein YP_006771244.1 3677090 R 1134782 CDS YP_006771245.1 410483699 13690305 3678104..3679585 1 NC_018650.1 COG3104 Dipeptide/tripeptide permease; dipeptide/tripeptide permease D 3679585 13690305 O3M_18085 Escherichia coli O104:H4 str. 2009EL-2050 dipeptide/tripeptide permease D YP_006771245.1 3678104 D 1134782 CDS YP_006771246.1 410483700 13690306 complement(3679627..3681045) 1 NC_018650.1 COG0415 Deoxyribodipyrimidine photolyase; deoxyribodipyrimidine photolyase 3681045 13690306 O3M_18090 Escherichia coli O104:H4 str. 2009EL-2050 deoxyribodipyrimidine photolyase YP_006771246.1 3679627 R 1134782 CDS YP_006771247.1 410483701 13690307 complement(3681042..3681551) 1 NC_018650.1 COG3272 Uncharacterized conserved protein; hypothetical protein 3681551 13690307 O3M_18095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771247.1 3681042 R 1134782 CDS YP_006771248.1 410483702 13690308 complement(3681699..3682385) 1 NC_018650.1 COG5433 Transposase; hypothetical protein 3682385 13690308 O3M_18100 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771248.1 3681699 R 1134782 CDS YP_006771249.1 410483703 13690309 complement(3682586..3682840) 1 NC_018650.1 COG5433 Transposase; transposase 3682840 13690309 O3M_18105 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771249.1 3682586 R 1134782 CDS YP_006771250.1 410483704 13690310 complement(3683066..3683635) 1 NC_018650.1 hypothetical protein 3683635 13690310 O3M_18110 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771250.1 3683066 R 1134782 CDS YP_006771251.1 410483705 13690311 complement(3683632..3685065) 1 NC_018650.1 COG3209 Rhs family protein; RhsC core protein 3685065 13690311 O3M_18115 Escherichia coli O104:H4 str. 2009EL-2050 RhsC core protein YP_006771251.1 3683632 R 1134782 CDS YP_006771252.1 410483706 13690312 complement(3685183..3685509) 1 NC_018650.1 hypothetical protein 3685509 13690312 O3M_18120 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771252.1 3685183 R 1134782 CDS YP_006771253.1 410483707 13690313 complement(3685509..3689702) 1 NC_018650.1 COG3209 Rhs family protein; rhsC element core protein RshC 3689702 13690313 O3M_18125 Escherichia coli O104:H4 str. 2009EL-2050 rhsC element core protein RshC YP_006771253.1 3685509 R 1134782 CDS YP_006771254.1 410483708 13690314 complement(3689945..3690151) 1 NC_018650.1 hypothetical protein 3690151 13690314 O3M_18130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771254.1 3689945 R 1134782 CDS YP_006771255.1 410483709 13690315 3690464..3690553 1 NC_018650.1 potassium ion accessory transporter subunit 3690553 13690315 O3M_18135 Escherichia coli O104:H4 str. 2009EL-2050 potassium ion accessory transporter subunit YP_006771255.1 3690464 D 1134782 CDS YP_006771256.1 410483710 13690316 3690553..3692226 1 NC_018650.1 COG2060 K+-transporting ATPase, A chain; potassium-transporting ATPase subunit A 3692226 13690316 O3M_18140 Escherichia coli O104:H4 str. 2009EL-2050 potassium-transporting ATPase subunit A YP_006771256.1 3690553 D 1134782 CDS YP_006771257.1 410483711 13690317 3692249..3694297 1 NC_018650.1 COG2216 High-affinity K+ transport system, ATPase chain B; potassium-transporting ATPase subunit B 3694297 13690317 O3M_18145 Escherichia coli O104:H4 str. 2009EL-2050 potassium-transporting ATPase subunit B YP_006771257.1 3692249 D 1134782 CDS YP_006771258.1 410483712 13690318 3694306..3694878 1 NC_018650.1 COG2156 K+-transporting ATPase, c chain; potassium-transporting ATPase subunit C 3694878 13690318 O3M_18150 Escherichia coli O104:H4 str. 2009EL-2050 potassium-transporting ATPase subunit C YP_006771258.1 3694306 D 1134782 CDS YP_006771259.1 410483713 13690319 3694871..3697555 1 NC_018650.1 COG2205 Osmosensitive K+ channel histidine kinase; sensor protein KdpD 3697555 13690319 O3M_18155 Escherichia coli O104:H4 str. 2009EL-2050 sensor protein KdpD YP_006771259.1 3694871 D 1134782 CDS YP_006771260.1 410483714 13690320 3697552..3698229 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator KdpE 3698229 13690320 O3M_18160 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator KdpE YP_006771260.1 3697552 D 1134782 CDS YP_006771261.1 410483715 13690321 3698919..3701117 1 NC_018650.1 COG1982 Arginine/lysine/ornithine decarboxylases; ornithine decarboxylase 3701117 13690321 O3M_18165 Escherichia coli O104:H4 str. 2009EL-2050 ornithine decarboxylase YP_006771261.1 3698919 D 1134782 CDS YP_006771262.1 410483716 13690322 3701114..3702433 1 NC_018650.1 COG0531 Amino acid transporters; putrescine transporter 3702433 potE 13690322 potE Escherichia coli O104:H4 str. 2009EL-2050 putrescine transporter YP_006771262.1 3701114 D 1134782 CDS YP_006771263.1 410483717 13690323 complement(3702489..3704129) 1 NC_018650.1 COG0033 Phosphoglucomutase; phosphoglucomutase 3704129 13690323 O3M_18175 Escherichia coli O104:H4 str. 2009EL-2050 phosphoglucomutase YP_006771263.1 3702489 R 1134782 CDS YP_006771264.1 410483718 13690324 complement(3704155..3704700) 1 NC_018650.1 COG3057 Negative regulator of replication initiationR; replication initiation regulator SeqA 3704700 13690324 O3M_18180 Escherichia coli O104:H4 str. 2009EL-2050 replication initiation regulator SeqA YP_006771264.1 3704155 R 1134782 CDS YP_006771265.1 410483719 13690325 3704885..3705649 1 NC_018650.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); acyl-CoA esterase 3705649 13690325 O3M_18185 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA esterase YP_006771265.1 3704885 D 1134782 CDS YP_006771266.1 410483720 13690326 3705789..3706082 1 NC_018650.1 LexA regulated protein 3706082 13690326 O3M_18190 Escherichia coli O104:H4 str. 2009EL-2050 LexA regulated protein YP_006771266.1 3705789 D 1134782 CDS YP_006771267.1 410483721 13690327 3706222..3706752 1 NC_018650.1 COG0716 Flavodoxins; flavodoxin FldA 3706752 13690327 O3M_18195 Escherichia coli O104:H4 str. 2009EL-2050 flavodoxin FldA YP_006771267.1 3706222 D 1134782 CDS YP_006771268.1 410483722 13690328 3706962..3707048 1 NC_018650.1 ryhB-regulated fur leader peptide 3707048 13690328 O3M_18200 Escherichia coli O104:H4 str. 2009EL-2050 ryhB-regulated fur leader peptide YP_006771268.1 3706962 D 1134782 CDS YP_006771269.1 410483723 13690329 3707041..3707487 1 NC_018650.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; ferric uptake regulator 3707487 fur 13690329 fur Escherichia coli O104:H4 str. 2009EL-2050 ferric uptake regulator YP_006771269.1 3707041 D 1134782 CDS YP_006771270.1 410483724 13690330 complement(3707571..3707897) 1 NC_018650.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein 3707897 13690330 O3M_18210 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771270.1 3707571 R 1134782 CDS YP_006771271.1 410483725 13690331 complement(3707947..3709353) 1 NC_018650.1 outer membrane porin 3709353 13690331 O3M_18215 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane porin YP_006771271.1 3707947 R 1134782 CDS YP_006771272.1 410483726 13690332 complement(3709799..3711463) 1 NC_018650.1 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutaminyl-tRNA synthetase 3711463 13690332 O3M_18220 Escherichia coli O104:H4 str. 2009EL-2050 glutaminyl-tRNA synthetase YP_006771272.1 3709799 R 1134782 CDS YP_006771273.1 410483727 13690333 complement(3711666..3713612) 1 NC_018650.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system N-acetyl glucosamine specific transporter subunit IIABC 3713612 13690333 O3M_18225 Escherichia coli O104:H4 str. 2009EL-2050 PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_006771273.1 3711666 R 1134782 CDS YP_006771274.1 410483728 13690334 3713945..3714745 1 NC_018650.1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; glucosamine-6-phosphate deaminase 3714745 nagB 13690334 nagB Escherichia coli O104:H4 str. 2009EL-2050 glucosamine-6-phosphate deaminase YP_006771274.1 3713945 D 1134782 CDS YP_006771275.1 410483729 13690335 3714805..3715953 1 NC_018650.1 COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 3715953 nagA 13690335 nagA Escherichia coli O104:H4 str. 2009EL-2050 N-acetylglucosamine-6-phosphate deacetylase YP_006771275.1 3714805 D 1134782 CDS YP_006771276.1 410483730 13690336 3715962..3717182 1 NC_018650.1 COG1940 Transcriptional regulator/sugar kinase; N-acetylglucosamine repressor 3717182 13690336 O3M_18240 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylglucosamine repressor YP_006771276.1 3715962 D 1134782 CDS YP_006771277.1 410483731 13690337 3717230..3717982 1 NC_018650.1 COG0647 Predicted sugar phosphatases of the HAD superfamily; UMP phosphatase 3717982 13690337 O3M_18245 Escherichia coli O104:H4 str. 2009EL-2050 UMP phosphatase YP_006771277.1 3717230 D 1134782 CDS YP_006771278.1 410483732 13690338 3718239..3719903 1 NC_018650.1 COG0367 Asparagine synthase (glutamine-hydrolyzing); asparagine synthetase B 3719903 asnB 13690338 asnB Escherichia coli O104:H4 str. 2009EL-2050 asparagine synthetase B YP_006771278.1 3718239 D 1134782 CDS YP_006771279.1 410483733 13690346 complement(3721141..3722316) 1 NC_018650.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 3722316 ubiF 13690346 ubiF Escherichia coli O104:H4 str. 2009EL-2050 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_006771279.1 3721141 R 1134782 CDS YP_006771280.1 410483734 13690347 3722462..3723886 1 NC_018650.1 COG0621 2-methylthioadenine synthetase; (dimethylallyl)adenosine tRNA methylthiotransferase 3723886 13690347 O3M_18260 Escherichia coli O104:H4 str. 2009EL-2050 (dimethylallyl)adenosine tRNA methylthiotransferase YP_006771280.1 3722462 D 1134782 CDS YP_006771281.1 410483735 13690348 3724000..3725079 1 NC_018650.1 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; PhoH family protein 3725079 13690348 O3M_18265 Escherichia coli O104:H4 str. 2009EL-2050 PhoH family protein YP_006771281.1 3724000 D 1134782 CDS YP_006771282.1 410483736 13690349 3725076..3725543 1 NC_018650.1 COG0319 Predicted metal-dependent hydrolase; metal-binding heat shock protein 3725543 13690349 O3M_18270 Escherichia coli O104:H4 str. 2009EL-2050 metal-binding heat shock protein YP_006771282.1 3725076 D 1134782 CDS YP_006771283.1 410483737 13690350 3725633..3726511 1 NC_018650.1 COG4535 Putative Mg2+ and Co2+ transporter CorC; magnesium/cobalt efflux protein CorC 3726511 13690350 O3M_18275 Escherichia coli O104:H4 str. 2009EL-2050 magnesium/cobalt efflux protein CorC YP_006771283.1 3725633 D 1134782 CDS YP_006771284.1 410483738 13690351 3726536..3728074 1 NC_018650.1 COG0815 Apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 3728074 lnt 13690351 lnt Escherichia coli O104:H4 str. 2009EL-2050 apolipoprotein N-acyltransferase YP_006771284.1 3726536 D 1134782 CDS YP_006771285.1 410483739 13690352 3730483..3731391 1 NC_018650.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamate and aspartate transporter subunit 3731391 13690352 O3M_18295 Escherichia coli O104:H4 str. 2009EL-2050 glutamate and aspartate transporter subunit YP_006771285.1 3730483 D 1134782 CDS YP_006771286.1 410483740 13690353 3731561..3732301 1 NC_018650.1 COG0765 ABC-type amino acid transport system, permease component; glutamate/aspartate transport system permease GltJ 3732301 13690353 O3M_18300 Escherichia coli O104:H4 str. 2009EL-2050 glutamate/aspartate transport system permease GltJ YP_006771286.1 3731561 D 1134782 CDS YP_006771287.1 410483741 13690354 3732301..3732975 1 NC_018650.1 COG0765 ABC-type amino acid transport system, permease component; glutamate/aspartate transport system permease GltK 3732975 13690354 O3M_18305 Escherichia coli O104:H4 str. 2009EL-2050 glutamate/aspartate transport system permease GltK YP_006771287.1 3732301 D 1134782 CDS YP_006771288.1 410483742 13690355 3732975..3733700 1 NC_018650.1 COG1126 ABC-type polar amino acid transport system, ATPase component; glutamate/aspartate transport ATP-binding protein gltL 3733700 13690355 O3M_18310 Escherichia coli O104:H4 str. 2009EL-2050 glutamate/aspartate transport ATP-binding protein gltL YP_006771288.1 3732975 D 1134782 CDS YP_006771289.1 410483743 13690356 3733818..3734753 1 NC_018650.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase 1 3734753 rihA 13690356 rihA Escherichia coli O104:H4 str. 2009EL-2050 ribonucleoside hydrolase 1 YP_006771289.1 3733818 D 1134782 CDS YP_006771290.1 410483744 13690357 3734837..3736507 1 NC_018650.1 COG0443 Molecular chaperone; molecular chaperone DnaK 3736507 13690357 O3M_18320 Escherichia coli O104:H4 str. 2009EL-2050 molecular chaperone DnaK YP_006771290.1 3734837 D 1134782 CDS YP_006771291.1 410483745 13690358 complement(3736567..3738018) 1 NC_018650.1 Hsc56 co-chaperone of HscC 3738018 13690358 O3M_18325 Escherichia coli O104:H4 str. 2009EL-2050 Hsc56 co-chaperone of HscC YP_006771291.1 3736567 R 1134782 CDS YP_006771292.1 410483746 13690359 complement(3738015..3738722) 1 NC_018650.1 hypothetical protein 3738722 13690359 O3M_18330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771292.1 3738015 R 1134782 CDS YP_006771293.1 410483747 13690360 3738823..3739377 1 NC_018650.1 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 3739377 13690360 O3M_18335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771293.1 3738823 D 1134782 CDS YP_006771294.1 410483748 13690361 complement(3739387..3740814) 1 NC_018650.1 COG2214 DnaJ-class molecular chaperone; DnaJ-class chaperone 3740814 13690361 O3M_18340 Escherichia coli O104:H4 str. 2009EL-2050 DnaJ-class chaperone YP_006771294.1 3739387 R 1134782 CDS YP_006771295.1 410483749 13690362 complement(3740811..3741518) 1 NC_018650.1 hypothetical protein 3741518 13690362 O3M_18345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771295.1 3740811 R 1134782 CDS YP_006771296.1 410483750 13690363 3741682..3742659 1 NC_018650.1 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 3742659 13690363 O3M_18350 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771296.1 3741682 D 1134782 CDS YP_006771297.1 410483751 13690364 complement(3742729..3743211) 1 NC_018650.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 3743211 13690364 O3M_18355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771297.1 3742729 R 1134782 CDS YP_006771298.1 410483752 13690365 3743446..3746028 1 NC_018650.1 COG0495 Leucyl-tRNA synthetase; leucyl-tRNA synthetase 3746028 leuS 13690365 leuS Escherichia coli O104:H4 str. 2009EL-2050 leucyl-tRNA synthetase YP_006771298.1 3743446 D 1134782 CDS YP_006771299.1 410483753 13690366 3746043..3746624 1 NC_018650.1 COG2980 Rare lipoprotein B; LPS-assembly lipoprotein RlpB 3746624 13690366 O3M_18365 Escherichia coli O104:H4 str. 2009EL-2050 LPS-assembly lipoprotein RlpB YP_006771299.1 3746043 D 1134782 CDS YP_006771300.1 410483754 13690367 3746624..3747655 1 NC_018650.1 COG1466 DNA polymerase III, delta subunit; DNA polymerase III subunit delta 3747655 holA 13690367 holA Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit delta YP_006771300.1 3746624 D 1134782 CDS YP_006771301.1 410483755 13690368 3747657..3748298 1 NC_018650.1 COG1057 Nicotinic acid mononucleotide adenylyltransferase; nicotinic acid mononucleotide adenylyltransferase 3748298 nadD 13690368 nadD Escherichia coli O104:H4 str. 2009EL-2050 nicotinic acid mononucleotide adenylyltransferase YP_006771301.1 3747657 D 1134782 CDS YP_006771302.1 410483756 13690369 3748322..3748933 1 NC_018650.1 COG0406 Fructose-2,6-bisphosphatase; alpha-ribazole phosphatase 3748933 13690369 O3M_18380 Escherichia coli O104:H4 str. 2009EL-2050 alpha-ribazole phosphatase YP_006771302.1 3748322 D 1134782 CDS YP_006771303.1 410483757 13690370 3749193..3749510 1 NC_018650.1 COG0799 Uncharacterized homolog of plant Iojap protein; ribosome-associated protein 3749510 13690370 O3M_18385 Escherichia coli O104:H4 str. 2009EL-2050 ribosome-associated protein YP_006771303.1 3749193 D 1134782 CDS YP_006771304.1 410483758 13690371 3749514..3749981 1 NC_018650.1 COG1576 Uncharacterized conserved protein; rRNA large subunit methyltransferase 3749981 13690371 O3M_18390 Escherichia coli O104:H4 str. 2009EL-2050 rRNA large subunit methyltransferase YP_006771304.1 3749514 D 1134782 CDS YP_006771305.1 410483759 13690372 3750012..3751913 1 NC_018650.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 2 3751913 13690372 O3M_18395 Escherichia coli O104:H4 str. 2009EL-2050 penicillin-binding protein 2 YP_006771305.1 3750012 D 1134782 CDS YP_006771306.1 410483760 13690373 3751916..3753028 1 NC_018650.1 COG0772 Bacterial cell division membrane protein; cell wall shape-determining protein 3753028 13690373 O3M_18400 Escherichia coli O104:H4 str. 2009EL-2050 cell wall shape-determining protein YP_006771306.1 3751916 D 1134782 CDS YP_006771307.1 410483761 13690374 3753039..3754127 1 NC_018650.1 COG0797 Lipoproteins; rare lipoprotein A 3754127 13690374 O3M_18405 Escherichia coli O104:H4 str. 2009EL-2050 rare lipoprotein A YP_006771307.1 3753039 D 1134782 CDS YP_006771308.1 410483762 13690375 3754266..3755477 1 NC_018650.1 COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 3755477 13690375 O3M_18410 Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-D-alanine carboxypeptidase YP_006771308.1 3754266 D 1134782 CDS YP_006771309.1 410483763 13690376 3755588..3755851 1 NC_018650.1 COG2921 Uncharacterized conserved protein; hypothetical protein 3755851 13690376 O3M_18415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771309.1 3755588 D 1134782 CDS YP_006771310.1 410483764 13690377 3755952..3756593 1 NC_018650.1 COG0321 Lipoate-protein ligase B; lipoate-protein ligase B 3756593 13690377 O3M_18420 Escherichia coli O104:H4 str. 2009EL-2050 lipoate-protein ligase B YP_006771310.1 3755952 D 1134782 CDS YP_006771311.1 410483765 13690378 complement(3756645..3756794) 1 NC_018650.1 COG0474 Cation transport ATPase; hypothetical protein 3756794 13690378 O3M_18425 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771311.1 3756645 R 1134782 CDS YP_006771312.1 410483766 13690379 3756852..3757805 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator 3757805 13690379 O3M_18430 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771312.1 3756852 D 1134782 CDS YP_006771313.1 410483767 13690380 3758014..3758979 1 NC_018650.1 COG0320 Lipoate synthase; lipoyl synthase 3758979 13690380 O3M_18435 Escherichia coli O104:H4 str. 2009EL-2050 lipoyl synthase YP_006771313.1 3758014 D 1134782 CDS YP_006771314.1 410483768 13690381 complement(3759080..3759283) 1 NC_018650.1 COG1826 Sec-independent protein secretion pathway components; twin arginine translocase protein E 3759283 tatE 13690381 tatE Escherichia coli O104:H4 str. 2009EL-2050 twin arginine translocase protein E YP_006771314.1 3759080 R 1134782 CDS YP_006771315.1 410483769 13690382 complement(3759412..3760200) 1 NC_018650.1 COG0388 Predicted amidohydrolase; hypothetical protein 3760200 13690382 O3M_18445 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771315.1 3759412 R 1134782 CDS YP_006771316.1 410483770 13690383 3760293..3760676 1 NC_018650.1 COG0239 Integral membrane protein possibly involved in chromosome condensation; chromosome condensation membrane protein 3760676 13690383 O3M_18450 Escherichia coli O104:H4 str. 2009EL-2050 chromosome condensation membrane protein YP_006771316.1 3760293 D 1134782 CDS YP_006771317.1 410483771 13690384 complement(3760730..3760939) 1 NC_018650.1 COG1278 Cold shock proteins; cold shock protein CspE 3760939 cspE 13690384 cspE Escherichia coli O104:H4 str. 2009EL-2050 cold shock protein CspE YP_006771317.1 3760730 R 1134782 CDS YP_006771318.1 410483772 13690385 complement(3761114..3761674) 1 NC_018650.1 phospholipid:lipid A palmitoyltransferase 3761674 pagP 13690385 pagP Escherichia coli O104:H4 str. 2009EL-2050 phospholipid:lipid A palmitoyltransferase YP_006771318.1 3761114 R 1134782 CDS YP_006771319.1 410483773 13690386 3762263..3763648 1 NC_018650.1 COG3069 C4-dicarboxylate transporter; C4-dicarboxylate transporter DcuC 3763648 dcuC 13690386 dcuC Escherichia coli O104:H4 str. 2009EL-2050 C4-dicarboxylate transporter DcuC YP_006771319.1 3762263 D 1134782 CDS YP_006771320.1 410483774 13690387 complement(3763689..3764369) 1 NC_018650.1 COG4565 Response regulator of citrate/malate metabolism; two-component response regulator DpiA 3764369 dpiA 13690387 dpiA Escherichia coli O104:H4 str. 2009EL-2050 two-component response regulator DpiA YP_006771320.1 3763689 R 1134782 CDS YP_006771321.1 410483775 13690388 complement(3764338..3765996) 1 NC_018650.1 COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; sensor histidine kinase DpiB 3765996 dpiB 13690388 dpiB Escherichia coli O104:H4 str. 2009EL-2050 sensor histidine kinase DpiB YP_006771321.1 3764338 R 1134782 CDS YP_006771322.1 410483776 13690389 3766376..3767434 1 NC_018650.1 COG3053 Citrate lyase synthetase; citrate lyase synthetase 3767434 13690389 O3M_18480 Escherichia coli O104:H4 str. 2009EL-2050 citrate lyase synthetase YP_006771322.1 3766376 D 1134782 CDS YP_006771323.1 410483777 13690390 3767449..3767745 1 NC_018650.1 COG3052 Citrate lyase, gamma subunit; citrate lyase subunit gamma 3767745 13690390 O3M_18485 Escherichia coli O104:H4 str. 2009EL-2050 citrate lyase subunit gamma YP_006771323.1 3767449 D 1134782 CDS YP_006771324.1 410483778 13690391 3767742..3768650 1 NC_018650.1 COG2301 Citrate lyase beta subunit; citrate lyase subunit beta 3768650 13690391 O3M_18490 Escherichia coli O104:H4 str. 2009EL-2050 citrate lyase subunit beta YP_006771324.1 3767742 D 1134782 CDS YP_006771325.1 410483779 13690392 3768661..3770193 1 NC_018650.1 COG3051 Citrate lyase, alpha subunit; citrate lyase subunit alpha 3770193 13690392 O3M_18495 Escherichia coli O104:H4 str. 2009EL-2050 citrate lyase subunit alpha YP_006771325.1 3768661 D 1134782 CDS YP_006771326.1 410483780 13690393 3770197..3770748 1 NC_018650.1 COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase); 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 3770748 citX 13690393 citX Escherichia coli O104:H4 str. 2009EL-2050 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_006771326.1 3770197 D 1134782 CDS YP_006771327.1 410483781 13690394 3770723..3771601 1 NC_018650.1 COG1767 Triphosphoribosyl-dephospho-CoA synthetase; triphosphoribosyl-dephospho-CoA synthase 3771601 citG 13690394 citG Escherichia coli O104:H4 str. 2009EL-2050 triphosphoribosyl-dephospho-CoA synthase YP_006771327.1 3770723 D 1134782 CDS YP_006771328.1 410483782 13690395 3771652..3773115 1 NC_018650.1 COG0471 Di- and tricarboxylate transporters; citrate/succinate antiporter CitT 3773115 13690395 O3M_18510 Escherichia coli O104:H4 str. 2009EL-2050 citrate/succinate antiporter CitT YP_006771328.1 3771652 D 1134782 CDS YP_006771329.1 410483783 13690396 3773229..3774035 1 NC_018650.1 COG3719 Ribonuclease I; ribonuclease I 3774035 13690396 O3M_18515 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease I YP_006771329.1 3773229 D 1134782 CDS YP_006771330.1 410483784 13690397 3774265..3774675 1 NC_018650.1 COG0782 Transcription elongation factor; nucleoside diphosphate kinase regulator 3774675 13690397 O3M_18520 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside diphosphate kinase regulator YP_006771330.1 3774265 D 1134782 CDS YP_006771331.1 410483785 13690398 complement(3774906..3776144) 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase zinc-binding dehydrogenase family protein 3776144 13690398 O3M_18525 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase zinc-binding dehydrogenase family protein YP_006771331.1 3774906 R 1134782 CDS YP_006771332.1 410483786 13690399 3776365..3776793 1 NC_018650.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspG 3776793 13690399 O3M_18530 Escherichia coli O104:H4 str. 2009EL-2050 universal stress protein UspG YP_006771332.1 3776365 D 1134782 CDS YP_006771333.1 410483787 13690400 complement(3776914..3778479) 1 NC_018650.1 COG3634 Alkyl hydroperoxide reductase, large subunit; alkyl hydroperoxide reductase subunit F 3778479 13690400 O3M_18535 Escherichia coli O104:H4 str. 2009EL-2050 alkyl hydroperoxide reductase subunit F YP_006771333.1 3776914 R 1134782 CDS YP_006771334.1 410483788 13690401 complement(3778608..3779171) 1 NC_018650.1 COG0450 Peroxiredoxin; alkyl hydroperoxide reductase subunit C 3779171 13690401 O3M_18540 Escherichia coli O104:H4 str. 2009EL-2050 alkyl hydroperoxide reductase subunit C YP_006771334.1 3778608 R 1134782 CDS YP_006771335.1 410483789 13690402 3779543..3780289 1 NC_018650.1 COG1651 Protein-disulfide isomerase; disulfide isomerase/thiol-disulfide oxidase 3780289 dsbG 13690402 dsbG Escherichia coli O104:H4 str. 2009EL-2050 disulfide isomerase/thiol-disulfide oxidase YP_006771335.1 3779543 D 1134782 CDS YP_006771336.1 410483790 13690403 3780499..3781401 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 3781401 13690403 O3M_18550 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006771336.1 3780499 D 1134782 CDS YP_006771337.1 410483791 13690404 3781548..3782768 1 NC_018650.1 COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase; phosphoadenosine phosphosulfate reductase family protein 3782768 13690404 O3M_18555 Escherichia coli O104:H4 str. 2009EL-2050 phosphoadenosine phosphosulfate reductase family protein YP_006771337.1 3781548 D 1134782 CDS YP_006771338.1 410483792 13690405 3782753..3783370 1 NC_018650.1 COG1475 Predicted transcriptional regulators; Immunoglobulin-binding regulator family protein 3783370 13690405 O3M_18560 Escherichia coli O104:H4 str. 2009EL-2050 Immunoglobulin-binding regulator family protein YP_006771338.1 3782753 D 1134782 CDS YP_006771339.1 410483793 13690406 complement(3783371..3784531) 1 NC_018650.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; methionine aminotransferase 3784531 13690406 O3M_18565 Escherichia coli O104:H4 str. 2009EL-2050 methionine aminotransferase YP_006771339.1 3783371 R 1134782 CDS YP_006771340.1 410483794 13690407 3784640..3785728 1 NC_018650.1 COG0371 Glycerol dehydrogenase and related enzymes; oxidoreductase 3785728 13690407 O3M_18570 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006771340.1 3784640 D 1134782 CDS YP_006771341.1 410483795 13690408 complement(3785738..3785935) 1 NC_018650.1 COG2879 Uncharacterized small protein; hypothetical protein 3785935 13690408 O3M_18575 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771341.1 3785738 R 1134782 CDS YP_006771342.1 410483796 13690409 complement(3786117..3788222) 1 NC_018650.1 COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein A 3788222 13690409 O3M_18580 Escherichia coli O104:H4 str. 2009EL-2050 carbon starvation protein A YP_006771342.1 3786117 R 1134782 CDS YP_006771343.1 410483797 13690410 complement(3788403..3788816) 1 NC_018650.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; thioesterase 3788816 13690410 O3M_18585 Escherichia coli O104:H4 str. 2009EL-2050 thioesterase YP_006771343.1 3788403 R 1134782 CDS YP_006771344.1 410483798 13690411 complement(3788819..3789565) 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 2,3-dihydroxybenzoate-2,3-dehydrogenase 3789565 13690411 O3M_18590 Escherichia coli O104:H4 str. 2009EL-2050 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_006771344.1 3788819 R 1134782 CDS YP_006771345.1 410483799 13690412 complement(3789565..3790422) 1 NC_018650.1 COG1535 Isochorismate hydrolase; isochorismatase 3790422 13690412 O3M_18595 Escherichia coli O104:H4 str. 2009EL-2050 isochorismatase YP_006771345.1 3789565 R 1134782 CDS YP_006771346.1 410483800 13690413 complement(3790436..3792046) 1 NC_018650.1 COG1021 Peptide arylation enzymes; enterobactin synthase subunit E 3792046 entE 13690413 entE Escherichia coli O104:H4 str. 2009EL-2050 enterobactin synthase subunit E YP_006771346.1 3790436 R 1134782 CDS YP_006771347.1 410483801 13690414 complement(3792056..3793231) 1 NC_018650.1 COG1169 Isochorismate synthase; isochorismate synthase EntC 3793231 13690414 O3M_18605 Escherichia coli O104:H4 str. 2009EL-2050 isochorismate synthase EntC YP_006771347.1 3792056 R 1134782 CDS YP_006771348.1 410483802 13690415 3793606..3794562 1 NC_018650.1 COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component; iron-enterobactin transporter periplasmic binding protein 3794562 13690415 O3M_18610 Escherichia coli O104:H4 str. 2009EL-2050 iron-enterobactin transporter periplasmic binding protein YP_006771348.1 3793606 D 1134782 CDS YP_006771349.1 410483803 13690416 complement(3794566..3795816) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; enterobactin exporter EntS 3795816 13690416 O3M_18615 Escherichia coli O104:H4 str. 2009EL-2050 enterobactin exporter EntS YP_006771349.1 3794566 R 1134782 CDS YP_006771350.1 410483804 13690417 3795927..3796931 1 NC_018650.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-enterobactin transporter membrane protein 3796931 13690417 O3M_18620 Escherichia coli O104:H4 str. 2009EL-2050 iron-enterobactin transporter membrane protein YP_006771350.1 3795927 D 1134782 CDS YP_006771351.1 410483805 13690418 3796928..3797920 1 NC_018650.1 COG4779 ABC-type enterobactin transport system, permease component; iron-enterobactin transporter permease 3797920 13690418 O3M_18625 Escherichia coli O104:H4 str. 2009EL-2050 iron-enterobactin transporter permease YP_006771351.1 3796928 D 1134782 CDS YP_006771352.1 410483806 13690419 3797917..3798732 1 NC_018650.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-enterobactin transporter ATP-binding protein 3798732 13690419 O3M_18630 Escherichia coli O104:H4 str. 2009EL-2050 iron-enterobactin transporter ATP-binding protein YP_006771352.1 3797917 D 1134782 CDS YP_006771353.1 410483807 13690420 complement(3798729..3799862) 1 NC_018650.1 COG3765 Chain length determinant protein; LPS O-antigen length regulator 3799862 13690420 O3M_18635 Escherichia coli O104:H4 str. 2009EL-2050 LPS O-antigen length regulator YP_006771353.1 3798729 R 1134782 CDS YP_006771354.1 410483808 13690421 complement(3800078..3803959) 1 NC_018650.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; enterobactin synthase subunit F 3803959 entF 13690421 entF Escherichia coli O104:H4 str. 2009EL-2050 enterobactin synthase subunit F YP_006771354.1 3800078 R 1134782 CDS YP_006771355.1 410483809 13690422 complement(3803956..3804174) 1 NC_018650.1 COG3251 Uncharacterized protein conserved in bacteria; hypothetical protein 3804174 13690422 O3M_18645 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771355.1 3803956 R 1134782 CDS YP_006771356.1 410483810 13690423 complement(3804177..3805301) 1 NC_018650.1 COG2382 Enterochelin esterase and related enzymes; enterobactin/ferric enterobactin esterase 3805301 13690423 O3M_18650 Escherichia coli O104:H4 str. 2009EL-2050 enterobactin/ferric enterobactin esterase YP_006771356.1 3804177 R 1134782 CDS YP_006771357.1 410483811 13690424 3805622..3807862 1 NC_018650.1 COG4771 Outer membrane receptor for ferrienterochelin and colicins; outer membrane receptor FepA 3807862 13690424 O3M_18655 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane receptor FepA YP_006771357.1 3805622 D 1134782 CDS YP_006771358.1 410483812 13690425 3808028..3808657 1 NC_018650.1 COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 3808657 13690425 O3M_18660 Escherichia coli O104:H4 str. 2009EL-2050 enterobactin synthase multienzyme complex phosphopantetheinyltransferase YP_006771358.1 3808028 D 1134782 CDS YP_006771359.1 410483813 13690426 complement(3808779..3808931) 1 NC_018650.1 regulatory peptide MokC 3808931 13690426 O3M_18665 Escherichia coli O104:H4 str. 2009EL-2050 regulatory peptide MokC YP_006771359.1 3808779 R 1134782 CDS YP_006771360.1 410483814 13690427 complement(3809442..3810554) 1 NC_018650.1 COG3385 FOG: Transposase and inactivated derivatives; transposase insL for insertion sequence IS186 3810554 13690427 O3M_18670 Escherichia coli O104:H4 str. 2009EL-2050 transposase insL for insertion sequence IS186 YP_006771360.1 3809442 R 1134782 CDS YP_006771361.1 410483815 13690428 complement(3810631..3810783) 1 NC_018650.1 hypothetical protein 3810783 13690428 O3M_18675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771361.1 3810631 R 1134782 CDS YP_006771362.1 410483816 13690429 complement(3811049..3811150) 1 NC_018650.1 hypothetical protein 3811150 13690429 O3M_18680 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771362.1 3811049 R 1134782 CDS YP_006771363.1 410483817 13690430 3811225..3812343 1 NC_018650.1 COG2170 Uncharacterized conserved protein; gamma-glutamyl:cysteine ligase 3812343 13690430 O3M_18685 Escherichia coli O104:H4 str. 2009EL-2050 gamma-glutamyl:cysteine ligase YP_006771363.1 3811225 D 1134782 CDS YP_006771364.1 410483818 13690431 3812409..3812657 1 NC_018650.1 inner membrane protein 3812657 13690431 O3M_18690 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771364.1 3812409 D 1134782 CDS YP_006771365.1 410483819 13690432 3812722..3813090 1 NC_018650.1 COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein 3813090 13690432 O3M_18695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771365.1 3812722 D 1134782 CDS YP_006771366.1 410483820 13690433 3813184..3813837 1 NC_018650.1 COG0778 Nitroreductase; dihydropteridine reductase 3813837 13690433 O3M_18700 Escherichia coli O104:H4 str. 2009EL-2050 dihydropteridine reductase YP_006771366.1 3813184 D 1134782 CDS YP_006771367.1 410483821 13690434 3813945..3815192 1 NC_018650.1 COG0668 Small-conductance mechanosensitive channel; mechanosensitive channel 3815192 13690434 O3M_18705 Escherichia coli O104:H4 str. 2009EL-2050 mechanosensitive channel YP_006771367.1 3813945 D 1134782 CDS YP_006771368.1 410483822 13690435 complement(3815260..3816636) 1 NC_018650.1 COG1113 Gamma-aminobutyrate permease and related permeases; phenylalanine transporter 3816636 13690435 O3M_18710 Escherichia coli O104:H4 str. 2009EL-2050 phenylalanine transporter YP_006771368.1 3815260 R 1134782 CDS YP_006771369.1 410483823 13690436 complement(3816738..3819881) 1 NC_018650.1 COG3696 Putative silver efflux pump; copper/silver efflux system, membrane component 3819881 13690436 O3M_18715 Escherichia coli O104:H4 str. 2009EL-2050 copper/silver efflux system, membrane component YP_006771369.1 3816738 R 1134782 CDS YP_006771370.1 410483824 13690437 complement(3819893..3821116) 1 NC_018650.1 COG0845 Membrane-fusion protein; copper/silver efflux system membrane fusion protein CusB 3821116 13690437 O3M_18720 Escherichia coli O104:H4 str. 2009EL-2050 copper/silver efflux system membrane fusion protein CusB YP_006771370.1 3819893 R 1134782 CDS YP_006771371.1 410483825 13690438 complement(3821132..3821464) 1 NC_018650.1 COG5569 Uncharacterized conserved protein; copper-binding protein 3821464 13690438 O3M_18725 Escherichia coli O104:H4 str. 2009EL-2050 copper-binding protein YP_006771371.1 3821132 R 1134782 CDS YP_006771372.1 410483826 13690439 complement(3821488..3822870) 1 NC_018650.1 COG1538 Outer membrane protein; copper/silver efflux system outer membrane protein CusC 3822870 13690439 O3M_18730 Escherichia coli O104:H4 str. 2009EL-2050 copper/silver efflux system outer membrane protein CusC YP_006771372.1 3821488 R 1134782 CDS YP_006771373.1 410483827 13690440 3823027..3823710 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional activator CusR 3823710 13690440 O3M_18735 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator CusR YP_006771373.1 3823027 D 1134782 CDS YP_006771374.1 410483828 13690441 3823700..3825148 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor kinase CusS 3825148 13690441 O3M_18740 Escherichia coli O104:H4 str. 2009EL-2050 sensor kinase CusS YP_006771374.1 3823700 D 1134782 CDS YP_006771375.1 410483829 13690442 3825885..3827786 1 NC_018650.1 COG3501 Uncharacterized protein conserved in bacteria; Rhs element Vgr protein 3827786 13690442 O3M_18745 Escherichia coli O104:H4 str. 2009EL-2050 Rhs element Vgr protein YP_006771375.1 3825885 D 1134782 CDS YP_006771376.1 410483830 13690443 3827814..3828275 1 NC_018650.1 COG5435 Uncharacterized conserved protein; hypothetical protein 3828275 13690443 O3M_18750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771376.1 3827814 D 1134782 CDS YP_006771377.1 410483831 13690444 3831823..3833157 1 NC_018650.1 COG3209 Rhs family protein; Rhs core protein with extension 3833157 13690444 O3M_18755 Escherichia coli O104:H4 str. 2009EL-2050 Rhs core protein with extension YP_006771377.1 3831823 D 1134782 CDS YP_006771378.1 410483832 13690445 3833154..3833405 1 NC_018650.1 hypothetical protein 3833405 13690445 O3M_18760 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771378.1 3833154 D 1134782 CDS YP_006771379.1 410483833 13690446 3833520..3833831 1 NC_018650.1 hypothetical protein 3833831 13690446 O3M_18765 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771379.1 3833520 D 1134782 CDS YP_006771380.1 410483834 13690447 3833935..3835071 1 NC_018650.1 COG5433 Transposase; transposase 3835071 13690447 O3M_18770 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771380.1 3833935 D 1134782 CDS YP_006771381.1 410483835 13690448 3835340..3837577 1 NC_018650.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; bacteriophage N4 adsorption protein B 3837577 nfrB 13690448 nfrB Escherichia coli O104:H4 str. 2009EL-2050 bacteriophage N4 adsorption protein B YP_006771381.1 3835340 D 1134782 CDS YP_006771382.1 410483836 13690449 3837564..3840536 1 NC_018650.1 COG0457 FOG: TPR repeat; bacteriophage N4 receptor, outer membrane subunit 3840536 13690449 O3M_18780 Escherichia coli O104:H4 str. 2009EL-2050 bacteriophage N4 receptor, outer membrane subunit YP_006771382.1 3837564 D 1134782 CDS YP_006771383.1 410483837 13690450 3840537..3841427 1 NC_018650.1 hypothetical protein 3841427 13690450 O3M_18785 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771383.1 3840537 D 1134782 CDS YP_006771384.1 410483838 13690451 3841610..3842371 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional activator EnvY 3842371 13690451 O3M_18790 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator EnvY YP_006771384.1 3841610 D 1134782 CDS YP_006771385.1 410483839 13690453 3842736..3843368 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulator FimZ 3843368 13690453 O3M_18800 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator FimZ YP_006771385.1 3842736 D 1134782 CDS YP_006771386.1 410483840 13690454 complement(3843371..3843886) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like adhesin protein SfmF 3843886 13690454 O3M_18805 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein SfmF YP_006771386.1 3843371 R 1134782 CDS YP_006771387.1 410483841 13690455 complement(3843897..3844904) 1 NC_018650.1 fimbrial-like adhesin 3844904 fimH 13690455 fimH Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin YP_006771387.1 3843897 R 1134782 CDS YP_006771388.1 410483842 13690456 complement(3844917..3847526) 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein FimD 3847526 13690456 O3M_18815 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane usher protein FimD YP_006771388.1 3844917 R 1134782 CDS YP_006771389.1 410483843 13690457 complement(3847557..3848249) 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein FimC 3848249 13690457 O3M_18820 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial chaperone protein FimC YP_006771389.1 3847557 R 1134782 CDS YP_006771390.1 410483844 13690458 complement(3848469..3849011) 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; type-1 fimbrial protein subunit A 3849011 13690458 O3M_18825 Escherichia coli O104:H4 str. 2009EL-2050 type-1 fimbrial protein subunit A YP_006771390.1 3848469 R 1134782 CDS YP_006771391.1 410483845 13690459 3849492..3850358 1 NC_018650.1 COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3850358 13690459 O3M_18830 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_006771391.1 3849492 D 1134782 CDS YP_006771392.1 410483846 13690460 3850360..3850572 1 NC_018650.1 COG2501 Uncharacterized conserved protein; hypothetical protein 3850572 13690460 O3M_18835 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771392.1 3850360 D 1134782 CDS YP_006771393.1 410483847 13690461 3850680..3851201 1 NC_018650.1 COG1988 Predicted membrane-bound metal-dependent hydrolases; inner membrane protein YbcI 3851201 13690461 O3M_18840 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YbcI YP_006771393.1 3850680 D 1134782 CDS YP_006771394.1 410483848 13690462 complement(3851237..3852622) 1 NC_018650.1 COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 3852622 cysS 13690462 cysS Escherichia coli O104:H4 str. 2009EL-2050 cysteinyl-tRNA synthetase YP_006771394.1 3851237 R 1134782 CDS YP_006771395.1 410483849 13690463 3852796..3853290 1 NC_018650.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase B 3853290 13690463 O3M_18850 Escherichia coli O104:H4 str. 2009EL-2050 peptidyl-prolyl cis-trans isomerase B YP_006771395.1 3852796 D 1134782 CDS YP_006771396.1 410483850 13690464 3853293..3854015 1 NC_018650.1 COG2908 Uncharacterized protein conserved in bacteria; UDP-2,3-diacylglucosamine hydrolase 3854015 13690464 O3M_18855 Escherichia coli O104:H4 str. 2009EL-2050 UDP-2,3-diacylglucosamine hydrolase YP_006771396.1 3853293 D 1134782 CDS YP_006771397.1 410483851 13690465 3854133..3854642 1 NC_018650.1 COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; phosphoribosylaminoimidazole carboxylase catalytic subunit 3854642 13690465 O3M_18860 Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_006771397.1 3854133 D 1134782 CDS YP_006771398.1 410483852 13690466 3854639..3855706 1 NC_018650.1 COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); phosphoribosylaminoimidazole carboxylase ATPase subunit 3855706 13690466 O3M_18865 Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_006771398.1 3854639 D 1134782 CDS YP_006771399.1 410483853 13690467 complement(3855901..3856794) 1 NC_018650.1 COG0549 Carbamate kinase; carbamate kinase 3856794 13690467 O3M_18870 Escherichia coli O104:H4 str. 2009EL-2050 carbamate kinase YP_006771399.1 3855901 R 1134782 CDS YP_006771400.1 410483854 13690468 complement(3856791..3857606) 1 NC_018650.1 hypothetical protein 3857606 13690468 O3M_18875 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771400.1 3856791 R 1134782 CDS YP_006771401.1 410483855 13690469 complement(3857617..3858876) 1 NC_018650.1 hypothetical protein 3858876 13690469 O3M_18880 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771401.1 3857617 R 1134782 CDS YP_006771402.1 410483856 13690470 complement(3858886..3860553) 1 NC_018650.1 COG0074 Succinyl-CoA synthetase, alpha subunit; membrane protein FdrA 3860553 13690470 O3M_18885 Escherichia coli O104:H4 str. 2009EL-2050 membrane protein FdrA YP_006771402.1 3858886 R 1134782 CDS YP_006771403.1 410483857 13690471 3860870..3861919 1 NC_018650.1 COG2055 Malate/L-lactate dehydrogenases; ureidoglycolate dehydrogenase 3861919 13690471 O3M_18890 Escherichia coli O104:H4 str. 2009EL-2050 ureidoglycolate dehydrogenase YP_006771403.1 3860870 D 1134782 CDS YP_006771404.1 410483858 13690472 3861941..3863176 1 NC_018650.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; allantoate amidohydrolase 3863176 13690472 O3M_18895 Escherichia coli O104:H4 str. 2009EL-2050 allantoate amidohydrolase YP_006771404.1 3861941 D 1134782 CDS YP_006771405.1 410483859 13690473 3863187..3863972 1 NC_018650.1 COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization; hypothetical protein 3863972 13690473 O3M_18900 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771405.1 3863187 D 1134782 CDS YP_006771406.1 410483860 13690474 complement(3864101..3865246) 1 NC_018650.1 COG1929 Glycerate kinase; glycerate kinase 3865246 13690474 O3M_18905 Escherichia coli O104:H4 str. 2009EL-2050 glycerate kinase YP_006771406.1 3864101 R 1134782 CDS YP_006771407.1 410483861 13690475 complement(3865268..3866569) 1 NC_018650.1 COG2233 Xanthine/uracil permeases; uracil/xanthine transporter 3866569 13690475 O3M_18910 Escherichia coli O104:H4 str. 2009EL-2050 uracil/xanthine transporter YP_006771407.1 3865268 R 1134782 CDS YP_006771408.1 410483862 13690476 complement(3866626..3867987) 1 NC_018650.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; allantoinase 3867987 13690476 O3M_18915 Escherichia coli O104:H4 str. 2009EL-2050 allantoinase YP_006771408.1 3866626 R 1134782 CDS YP_006771409.1 410483863 13690477 complement(3868047..3869501) 1 NC_018650.1 COG1953 Cytosine/uracil/thiamine/allantoin permeases; allantoin permease 3869501 13690477 O3M_18920 Escherichia coli O104:H4 str. 2009EL-2050 allantoin permease YP_006771409.1 3868047 R 1134782 CDS YP_006771410.1 410483864 13690478 complement(3869670..3870548) 1 NC_018650.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; tartronate semialdehyde reductase 3870548 13690478 O3M_18925 Escherichia coli O104:H4 str. 2009EL-2050 tartronate semialdehyde reductase YP_006771410.1 3869670 R 1134782 CDS YP_006771411.1 410483865 13690479 complement(3870648..3871424) 1 NC_018650.1 COG3622 Hydroxypyruvate isomerase; hydroxypyruvate isomerase 3871424 13690479 O3M_18930 Escherichia coli O104:H4 str. 2009EL-2050 hydroxypyruvate isomerase YP_006771411.1 3870648 R 1134782 CDS YP_006771412.1 410483866 13690480 complement(3871437..3873218) 1 NC_018650.1 COG3960 Glyoxylate carboligase; glyoxylate carboligase 3873218 13690480 O3M_18935 Escherichia coli O104:H4 str. 2009EL-2050 glyoxylate carboligase YP_006771412.1 3871437 R 1134782 CDS YP_006771413.1 410483867 13690481 complement(3873308..3874123) 1 NC_018650.1 COG1414 Transcriptional regulator; DNA-binding transcriptional repressor AllR 3874123 13690481 O3M_18940 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor AllR YP_006771413.1 3873308 R 1134782 CDS YP_006771414.1 410483868 13690482 complement(3874201..3874683) 1 NC_018650.1 COG3194 Ureidoglycolate hydrolase; ureidoglycolate hydrolase 3874683 13690482 O3M_18945 Escherichia coli O104:H4 str. 2009EL-2050 ureidoglycolate hydrolase YP_006771414.1 3874201 R 1134782 CDS YP_006771415.1 410483869 13690483 3874913..3875839 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional activator AllS 3875839 13690483 O3M_18950 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator AllS YP_006771415.1 3874913 D 1134782 CDS YP_006771416.1 410483870 13690484 3875908..3877002 1 NC_018650.1 COG2603 Predicted ATPase; tRNA 2-selenouridine synthase 3877002 13690484 O3M_18955 Escherichia coli O104:H4 str. 2009EL-2050 tRNA 2-selenouridine synthase YP_006771416.1 3875908 D 1134782 CDS YP_006771417.1 410483871 13690485 3877118..3877516 1 NC_018650.1 regulator with homeodomain-like DNA binding domain 3877516 13690485 O3M_18960 Escherichia coli O104:H4 str. 2009EL-2050 regulator with homeodomain-like DNA binding domain YP_006771417.1 3877118 D 1134782 CDS YP_006771418.1 410483872 13690486 complement(3878003..3878494) 1 NC_018650.1 hypothetical protein 3878494 13690486 O3M_18965 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771418.1 3878003 R 1134782 CDS YP_006771419.1 410483873 13690487 complement(3878475..3879185) 1 NC_018650.1 COG3209 Rhs family protein; rhs-like protein 3879185 13690487 O3M_18970 Escherichia coli O104:H4 str. 2009EL-2050 rhs-like protein YP_006771419.1 3878475 R 1134782 CDS YP_006771420.1 410483874 13690488 complement(3879185..3879553) 1 NC_018650.1 hypothetical protein 3879553 13690488 O3M_18975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771420.1 3879185 R 1134782 CDS YP_006771421.1 410483875 13690489 complement(3879593..3883882) 1 NC_018650.1 COG3209 Rhs family protein; rhsD element protein 3883882 13690489 O3M_18980 Escherichia coli O104:H4 str. 2009EL-2050 rhsD element protein YP_006771421.1 3879593 R 1134782 CDS YP_006771422.1 410483876 13690490 complement(3884312..3886726) 1 NC_018650.1 COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component; ABC transporter permease 3886726 13690490 O3M_18985 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter permease YP_006771422.1 3884312 R 1134782 CDS YP_006771423.1 410483877 13690491 complement(3886723..3887409) 1 NC_018650.1 COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component; ABC transporter ATP-binding protein 3887409 13690491 O3M_18990 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006771423.1 3886723 R 1134782 CDS YP_006771424.1 410483878 13690492 3887377..3888003 1 NC_018650.1 COG2755 Lysophospholipase L1 and related esterases; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 3888003 13690492 O3M_18995 Escherichia coli O104:H4 str. 2009EL-2050 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_006771424.1 3887377 D 1134782 CDS YP_006771425.1 410483879 13690493 3888032..3888802 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 3888802 13690493 O3M_19000 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006771425.1 3888032 D 1134782 CDS YP_006771426.1 410483880 13690494 3888863..3889717 1 NC_018650.1 COG3118 Thioredoxin domain-containing protein; thioredoxin-like protein 3889717 13690494 O3M_19005 Escherichia coli O104:H4 str. 2009EL-2050 thioredoxin-like protein YP_006771426.1 3888863 D 1134782 CDS YP_006771427.1 410483881 13690495 complement(3889780..3890559) 1 NC_018650.1 COG0390 ABC-type uncharacterized transport system, permease component; metal resistance protein 3890559 13690495 O3M_19010 Escherichia coli O104:H4 str. 2009EL-2050 metal resistance protein YP_006771427.1 3889780 R 1134782 CDS YP_006771428.1 410483882 13690496 complement(3890546..3891223) 1 NC_018650.1 COG4619 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATP-binding protein 3891223 13690496 O3M_19015 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006771428.1 3890546 R 1134782 CDS YP_006771429.1 410483883 13690497 3891369..3892286 1 NC_018650.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; protease 3892286 13690497 O3M_19020 Escherichia coli O104:H4 str. 2009EL-2050 protease YP_006771429.1 3891369 D 1134782 CDS YP_006771430.1 410483884 13690498 3892283..3892741 1 NC_018650.1 COG1585 Membrane protein implicated in regulation of membrane protease activity; nodulation efficiency family protein 3892741 13690498 O3M_19025 Escherichia coli O104:H4 str. 2009EL-2050 nodulation efficiency family protein YP_006771430.1 3892283 D 1134782 CDS YP_006771431.1 410483885 13690499 complement(3892742..3893149) 1 NC_018650.1 COG0789 Predicted transcriptional regulators; DNA-binding transcriptional regulator CueR 3893149 13690499 O3M_19030 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator CueR YP_006771431.1 3892742 R 1134782 CDS YP_006771432.1 410483886 13690500 complement(3893274..3894566) 1 NC_018650.1 COG0531 Amino acid transporters; transporter 3894566 13690500 O3M_19035 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771432.1 3893274 R 1134782 CDS YP_006771433.1 410483887 13690501 complement(3894569..3895501) 1 NC_018650.1 COG2066 Glutaminase; glutaminase 3895501 13690501 O3M_19040 Escherichia coli O104:H4 str. 2009EL-2050 glutaminase YP_006771433.1 3894569 R 1134782 CDS YP_006771434.1 410483888 13690502 3895763..3898267 1 NC_018650.1 COG2217 Cation transport ATPase; copper exporting ATPase 3898267 copA 13690502 copA Escherichia coli O104:H4 str. 2009EL-2050 copper exporting ATPase YP_006771434.1 3895763 D 1134782 CDS YP_006771435.1 410483889 13690503 complement(3898381..3898722) 1 NC_018650.1 COG3093 Plasmid maintenance system antidote protein; DNA-binding transcriptional regulator 3898722 13690503 O3M_19050 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771435.1 3898381 R 1134782 CDS YP_006771436.1 410483890 13690504 3898860..3899654 1 NC_018650.1 COG3735 Uncharacterized protein conserved in bacteria; hypothetical protein 3899654 13690504 O3M_19055 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771436.1 3898860 D 1134782 CDS YP_006771437.1 410483891 13690505 3899858..3900337 1 NC_018650.1 COG2606 Uncharacterized conserved protein; hypothetical protein 3900337 13690505 O3M_19060 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771437.1 3899858 D 1134782 CDS YP_006771438.1 410483892 13690506 complement(3900374..3902026) 1 NC_018650.1 COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; bifunctional UDP-sugar hydrolase/5'-nucleotidase 3902026 ushA 13690506 ushA Escherichia coli O104:H4 str. 2009EL-2050 bifunctional UDP-sugar hydrolase/5'-nucleotidase YP_006771438.1 3900374 R 1134782 CDS YP_006771439.1 410483893 13690507 3902244..3903464 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; fosmidomycin efflux system, member of the major facilitator superfamily protein 3903464 13690507 O3M_19070 Escherichia coli O104:H4 str. 2009EL-2050 fosmidomycin efflux system, member of the major facilitator superfamily protein YP_006771439.1 3902244 D 1134782 CDS YP_006771440.1 410483894 13690508 3903702..3905378 1 NC_018650.1 COG4651 Kef-type K+ transport system, predicted NAD-binding component; cation:proton antiport protein 3905378 13690508 O3M_19075 Escherichia coli O104:H4 str. 2009EL-2050 cation:proton antiport protein YP_006771440.1 3903702 D 1134782 CDS YP_006771441.1 410483895 13690509 complement(3905511..3906815) 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; inosine/guanosine kinase 3906815 13690509 O3M_19080 Escherichia coli O104:H4 str. 2009EL-2050 inosine/guanosine kinase YP_006771441.1 3905511 R 1134782 CDS YP_006771442.1 410483896 13690510 3906967..3907926 1 NC_018650.1 COG0657 Esterase/lipase; acetyl esterase 3907926 13690510 O3M_19085 Escherichia coli O104:H4 str. 2009EL-2050 acetyl esterase YP_006771442.1 3906967 D 1134782 CDS YP_006771443.1 410483897 13690511 complement(3907923..3908885) 1 NC_018650.1 COG0276 Protoheme ferro-lyase (ferrochelatase); ferrochelatase 3908885 hemH 13690511 hemH Escherichia coli O104:H4 str. 2009EL-2050 ferrochelatase YP_006771443.1 3907923 R 1134782 CDS YP_006771444.1 410483898 13690512 complement(3909121..3909765) 1 NC_018650.1 COG0563 Adenylate kinase and related kinases; adenylate kinase 3909765 adk 13690512 adk Escherichia coli O104:H4 str. 2009EL-2050 adenylate kinase YP_006771444.1 3909121 R 1134782 CDS YP_006771445.1 410483899 13690513 complement(3909946..3911820) 1 NC_018650.1 COG0326 Molecular chaperone, HSP90 family; heat shock protein 90 3911820 13690513 O3M_19100 Escherichia coli O104:H4 str. 2009EL-2050 heat shock protein 90 YP_006771445.1 3909946 R 1134782 CDS YP_006771446.1 410483900 13690514 complement(3911930..3912535) 1 NC_018650.1 COG0353 Recombinational DNA repair protein (RecF pathway); recombination protein RecR 3912535 recR 13690514 recR Escherichia coli O104:H4 str. 2009EL-2050 recombination protein RecR YP_006771446.1 3911930 R 1134782 CDS YP_006771447.1 410483901 13690515 complement(3912535..3912864) 1 NC_018650.1 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 3912864 13690515 O3M_19110 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771447.1 3912535 R 1134782 CDS YP_006771448.1 410483902 13690516 complement(3912917..3914848) 1 NC_018650.1 COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunits gamma and tau 3914848 13690516 O3M_19115 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunits gamma and tau YP_006771448.1 3912917 R 1134782 CDS YP_006771449.1 410483903 13690517 complement(3914977..3915528) 1 NC_018650.1 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine phosphoribosyltransferase 3915528 13690517 O3M_19120 Escherichia coli O104:H4 str. 2009EL-2050 adenine phosphoribosyltransferase YP_006771449.1 3914977 R 1134782 CDS YP_006771450.1 410483904 13690518 complement(3915681..3916058) 1 NC_018650.1 COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein 3916058 13690518 O3M_19125 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771450.1 3915681 R 1134782 CDS YP_006771451.1 410483905 13690519 3916128..3916655 1 NC_018650.1 COG3923 Primosomal replication protein N''; primosomal replication protein N'' 3916655 13690519 O3M_19130 Escherichia coli O104:H4 str. 2009EL-2050 primosomal replication protein N'' YP_006771451.1 3916128 D 1134782 CDS YP_006771452.1 410483906 13690520 3916669..3916830 1 NC_018650.1 hypothetical protein 3916830 13690520 O3M_19135 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771452.1 3916669 D 1134782 CDS YP_006771453.1 410483907 13690521 3916864..3917007 1 NC_018650.1 hypothetical protein 3917007 13690521 O3M_19140 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771453.1 3916864 D 1134782 CDS YP_006771454.1 410483908 13690522 complement(3917042..3920404) 1 NC_018650.1 COG3264 Small-conductance mechanosensitive channel; hypothetical protein 3920404 13690522 O3M_19145 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771454.1 3917042 R 1134782 CDS YP_006771455.1 410483909 13690523 complement(3920532..3921179) 1 NC_018650.1 COG1309 Transcriptional regulator; DNA-binding transcriptional repressor AcrR 3921179 13690523 O3M_19150 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor AcrR YP_006771455.1 3920532 R 1134782 CDS YP_006771456.1 410483910 13690524 3921321..3922514 1 NC_018650.1 COG0845 Membrane-fusion protein; multidrug efflux system transporter AcrA 3922514 13690524 O3M_19155 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system transporter AcrA YP_006771456.1 3921321 D 1134782 CDS YP_006771457.1 410483911 13690525 3922537..3925686 1 NC_018650.1 COG0841 Cation/multidrug efflux pump; multidrug efflux system protein AcrB 3925686 13690525 O3M_19160 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein AcrB YP_006771457.1 3922537 D 1134782 CDS YP_006771458.1 410483912 13690526 3926232..3926606 1 NC_018650.1 Hha toxicity attenuator 3926606 13690526 O3M_19165 Escherichia coli O104:H4 str. 2009EL-2050 Hha toxicity attenuator YP_006771458.1 3926232 D 1134782 CDS YP_006771459.1 410483913 13690527 3926632..3926850 1 NC_018650.1 modulator of gene expression, with H-NS; hemolysin expression-modulating protein 3926850 13690527 O3M_19170 Escherichia coli O104:H4 str. 2009EL-2050 hemolysin expression-modulating protein YP_006771459.1 3926632 D 1134782 CDS YP_006771460.1 410483914 13690528 3927021..3927572 1 NC_018650.1 COG0110 Acetyltransferase (isoleucine patch superfamily); maltose O-acetyltransferase 3927572 13690528 O3M_19175 Escherichia coli O104:H4 str. 2009EL-2050 maltose O-acetyltransferase YP_006771460.1 3927021 D 1134782 CDS YP_006771461.1 410483915 13690529 3927688..3928158 1 NC_018650.1 hypothetical protein 3928158 13690529 O3M_19180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771461.1 3927688 D 1134782 CDS YP_006771462.1 410483916 13690530 3928322..3929872 1 NC_018650.1 COG4943 Predicted signal transduction protein containing sensor and EAL domains; hypothetical protein 3929872 13690530 O3M_19185 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771462.1 3928322 D 1134782 CDS YP_006771463.1 410483917 13690531 complement(3929914..3930267) 1 NC_018650.1 COG5507 Uncharacterized conserved protein; hypothetical protein 3930267 13690531 O3M_19190 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771463.1 3929914 R 1134782 CDS YP_006771464.1 410483918 13690532 3930568..3930957 1 NC_018650.1 COG3695 Predicted methylated DNA-protein cysteine methyltransferase; methylated-DNA-[protein]-cysteine S-methyltransferase 3930957 13690532 O3M_19195 Escherichia coli O104:H4 str. 2009EL-2050 methylated-DNA-[protein]-cysteine S-methyltransferase YP_006771464.1 3930568 D 1134782 CDS YP_006771465.1 410483919 13690533 complement(3930988..3931560) 1 NC_018650.1 COG3126 Uncharacterized protein conserved in bacteria; lipoprotein 3931560 13690533 O3M_19200 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006771465.1 3930988 R 1134782 CDS YP_006771466.1 410483920 13690534 3931778..3932638 1 NC_018650.1 COG1946 Acyl-CoA thioesterase; acyl-CoA thioesterase II 3932638 13690534 O3M_19205 Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA thioesterase II YP_006771466.1 3931778 D 1134782 CDS YP_006771467.1 410483921 13690535 complement(3932687..3933973) 1 NC_018650.1 COG0004 Ammonia permease; ammonium transporter 3933973 13690535 O3M_19210 Escherichia coli O104:H4 str. 2009EL-2050 ammonium transporter YP_006771467.1 3932687 R 1134782 CDS YP_006771468.1 410483922 13690536 complement(3934003..3934341) 1 NC_018650.1 COG0347 Nitrogen regulatory protein PII; glutamine synthetase 3934341 13690536 O3M_19215 Escherichia coli O104:H4 str. 2009EL-2050 glutamine synthetase YP_006771468.1 3934003 R 1134782 CDS YP_006771469.1 410483923 13690537 complement(3934522..3936303) 1 NC_018650.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug transporter membrane\ATP-binding components 3936303 13690537 O3M_19220 Escherichia coli O104:H4 str. 2009EL-2050 multidrug transporter membrane\ATP-binding components YP_006771469.1 3934522 R 1134782 CDS YP_006771470.1 410483924 13690538 complement(3936296..3938068) 1 NC_018650.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug transporter membrane\ATP-binding components 3938068 13690538 O3M_19225 Escherichia coli O104:H4 str. 2009EL-2050 multidrug transporter membrane\ATP-binding components YP_006771470.1 3936296 R 1134782 CDS YP_006771471.1 410483925 13690539 complement(3938098..3938556) 1 NC_018650.1 COG1522 Transcriptional regulators; LRP-like transcriptional regulator 3938556 13690539 O3M_19230 Escherichia coli O104:H4 str. 2009EL-2050 LRP-like transcriptional regulator YP_006771471.1 3938098 R 1134782 CDS YP_006771472.1 410483926 13690540 complement(3938709..3939527) 1 NC_018650.1 COG0561 Predicted hydrolases of the HAD superfamily; thiamin pyrimidine pyrophosphate hydrolase 3939527 13690540 O3M_19235 Escherichia coli O104:H4 str. 2009EL-2050 thiamin pyrimidine pyrophosphate hydrolase YP_006771472.1 3938709 R 1134782 CDS YP_006771473.1 410483927 13690541 3939627..3941327 1 NC_018650.1 COG4533 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein 3941327 13690541 O3M_19240 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771473.1 3939627 D 1134782 CDS YP_006771474.1 410483928 13690542 3941392..3942087 1 NC_018650.1 COG0603 Predicted PP-loop superfamily ATPase; queuosine biosynthesis protein QueC 3942087 13690542 O3M_19245 Escherichia coli O104:H4 str. 2009EL-2050 queuosine biosynthesis protein QueC YP_006771474.1 3941392 D 1134782 CDS YP_006771475.1 410483929 13690543 complement(3942139..3942537) 1 NC_018650.1 COG0824 Predicted thioesterase; thioesterase superfamily protein 3942537 13690543 O3M_19250 Escherichia coli O104:H4 str. 2009EL-2050 thioesterase superfamily protein YP_006771475.1 3942139 R 1134782 CDS YP_006771476.1 410483930 13690544 complement(3942631..3943002) 1 NC_018650.1 COG1555 DNA uptake protein and related DNA-binding proteins; hypothetical protein 3943002 13690544 O3M_19255 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771476.1 3942631 R 1134782 CDS YP_006771477.1 410483931 13690545 complement(3943153..3945024) 1 NC_018650.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; chaperone 3945024 13690545 O3M_19260 Escherichia coli O104:H4 str. 2009EL-2050 chaperone YP_006771477.1 3943153 R 1134782 CDS YP_006771478.1 410483932 13690546 complement(3945216..3945488) 1 NC_018650.1 COG0776 Bacterial nucleoid DNA-binding protein; transcriptional regulator HU subunit beta 3945488 13690546 O3M_19265 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator HU subunit beta YP_006771478.1 3945216 R 1134782 CDS YP_006771479.1 410483933 13690547 complement(3945697..3948051) 1 NC_018650.1 COG0466 ATP-dependent Lon protease, bacterial type; DNA-binding ATP-dependent protease La 3948051 13690547 O3M_19270 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding ATP-dependent protease La YP_006771479.1 3945697 R 1134782 CDS YP_006771480.1 410483934 13690548 complement(3948239..3949513) 1 NC_018650.1 COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease ATP-binding subunit ClpX 3949513 clpX 13690548 clpX Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent protease ATP-binding subunit ClpX YP_006771480.1 3948239 R 1134782 CDS YP_006771481.1 410483935 13690549 3949540..3949740 1 NC_018650.1 hypothetical protein 3949740 13690549 O3M_19280 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771481.1 3949540 D 1134782 CDS YP_006771482.1 410483936 13690550 complement(3949639..3950262) 1 NC_018650.1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease proteolytic subunit 3950262 clpP 13690550 clpP Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent Clp protease proteolytic subunit YP_006771482.1 3949639 R 1134782 CDS YP_006771483.1 410483937 13690551 complement(3950508..3951806) 1 NC_018650.1 COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); trigger factor 3951806 tig 13690551 tig Escherichia coli O104:H4 str. 2009EL-2050 trigger factor YP_006771483.1 3950508 R 1134782 CDS YP_006771484.1 410483938 13690552 complement(3951953..3952141) 1 NC_018650.1 hypothetical protein 3952141 13690552 O3M_19295 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771484.1 3951953 R 1134782 CDS YP_006771485.1 410483939 13690553 complement(3952150..3952467) 1 NC_018650.1 COG0271 Stress-induced morphogen (activity unknown); transcriptional regulator BolA 3952467 13690553 O3M_19300 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator BolA YP_006771485.1 3952150 R 1134782 CDS YP_006771486.1 410483940 13690554 3952772..3953350 1 NC_018650.1 COG3056 Uncharacterized lipoprotein; hypothetical protein 3953350 13690554 O3M_19305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771486.1 3952772 D 1134782 CDS YP_006771487.1 410483941 13690555 3953394..3954869 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; muropeptide transporter 3954869 ampG 13690555 ampG Escherichia coli O104:H4 str. 2009EL-2050 muropeptide transporter YP_006771487.1 3953394 D 1134782 CDS YP_006771488.1 410483942 13690556 3955329..3956276 1 NC_018650.1 COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome o ubiquinol oxidase subunit II 3956276 13690556 O3M_19315 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome o ubiquinol oxidase subunit II YP_006771488.1 3955329 D 1134782 CDS YP_006771489.1 410483943 13690557 3956298..3958289 1 NC_018650.1 COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome o ubiquinol oxidase subunit I 3958289 13690557 O3M_19320 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome o ubiquinol oxidase subunit I YP_006771489.1 3956298 D 1134782 CDS YP_006771490.1 410483944 13690558 3958279..3958893 1 NC_018650.1 COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; cytochrome o ubiquinol oxidase subunit III 3958893 13690558 O3M_19325 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome o ubiquinol oxidase subunit III YP_006771490.1 3958279 D 1134782 CDS YP_006771491.1 410483945 13690559 3958893..3959222 1 NC_018650.1 COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4; cytochrome o ubiquinol oxidase subunit IV 3959222 13690559 O3M_19330 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome o ubiquinol oxidase subunit IV YP_006771491.1 3958893 D 1134782 CDS YP_006771492.1 410483946 13690560 3959234..3960124 1 NC_018650.1 COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor); protoheme IX farnesyltransferase 3960124 13690560 O3M_19335 Escherichia coli O104:H4 str. 2009EL-2050 protoheme IX farnesyltransferase YP_006771492.1 3959234 D 1134782 CDS YP_006771493.1 410483947 13690561 3960309..3960620 1 NC_018650.1 COG4453 Uncharacterized protein conserved in bacteria; hypothetical protein 3960620 13690561 O3M_19340 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771493.1 3960309 D 1134782 CDS YP_006771494.1 410483948 13690562 3960604..3961146 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 3961146 13690562 O3M_19345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771494.1 3960604 D 1134782 CDS YP_006771495.1 410483949 13690563 complement(3961202..3962197) 1 NC_018650.1 COG0790 FOG: TPR repeat, SEL1 subfamily; zinc-dependent hydrolase 3962197 13690563 O3M_19350 Escherichia coli O104:H4 str. 2009EL-2050 zinc-dependent hydrolase YP_006771495.1 3961202 R 1134782 CDS YP_006771496.1 410483950 13690564 3962545..3963909 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; major facilitator family transporter protein 3963909 13690564 O3M_19355 Escherichia coli O104:H4 str. 2009EL-2050 major facilitator family transporter protein YP_006771496.1 3962545 D 1134782 CDS YP_006771497.1 410483951 13690565 complement(3964037..3964528) 1 NC_018650.1 COG1666 Uncharacterized protein conserved in bacteria; nucleotide-binding protein 3964528 13690565 O3M_19360 Escherichia coli O104:H4 str. 2009EL-2050 nucleotide-binding protein YP_006771497.1 3964037 R 1134782 CDS YP_006771498.1 410483952 13690566 3964696..3965607 1 NC_018650.1 COG1893 Ketopantoate reductase; 2-dehydropantoate 2-reductase 3965607 13690566 O3M_19365 Escherichia coli O104:H4 str. 2009EL-2050 2-dehydropantoate 2-reductase YP_006771498.1 3964696 D 1134782 CDS YP_006771499.1 410483953 13690567 3965570..3966160 1 NC_018650.1 COG0693 Putative intracellular protease/amidase; oxidative-stress-resistance chaperone 3966160 13690567 O3M_19370 Escherichia coli O104:H4 str. 2009EL-2050 oxidative-stress-resistance chaperone YP_006771499.1 3965570 D 1134782 CDS YP_006771500.1 410483954 13690568 complement(3966214..3967662) 1 NC_018650.1 COG0301 Thiamine biosynthesis ATP pyrophosphatase; tRNA s(4)U8 sulfurtransferase 3967662 13690568 O3M_19375 Escherichia coli O104:H4 str. 2009EL-2050 tRNA s(4)U8 sulfurtransferase YP_006771500.1 3966214 R 1134782 CDS YP_006771501.1 410483955 13690569 3967868..3968110 1 NC_018650.1 COG1722 Exonuclease VII small subunit; exodeoxyribonuclease VII small subunit 3968110 13690569 O3M_19380 Escherichia coli O104:H4 str. 2009EL-2050 exodeoxyribonuclease VII small subunit YP_006771501.1 3967868 D 1134782 CDS YP_006771502.1 410483956 13690570 3968110..3969009 1 NC_018650.1 COG0142 Geranylgeranyl pyrophosphate synthase; geranyltranstransferase 3969009 13690570 O3M_19385 Escherichia coli O104:H4 str. 2009EL-2050 geranyltranstransferase YP_006771502.1 3968110 D 1134782 CDS YP_006771503.1 410483957 13690571 3969034..3970896 1 NC_018650.1 COG1154 Deoxyxylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 3970896 13690571 O3M_19390 Escherichia coli O104:H4 str. 2009EL-2050 1-deoxy-D-xylulose-5-phosphate synthase YP_006771503.1 3969034 D 1134782 CDS YP_006771504.1 410483958 13690572 3970951..3971925 1 NC_018650.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 3971925 13690572 O3M_19395 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006771504.1 3970951 D 1134782 CDS YP_006771505.1 410483959 13690573 complement(3971979..3972497) 1 NC_018650.1 COG1267 Phosphatidylglycerophosphatase A and related proteins; phosphatidylglycerophosphatase A 3972497 13690573 O3M_19400 Escherichia coli O104:H4 str. 2009EL-2050 phosphatidylglycerophosphatase A YP_006771505.1 3971979 R 1134782 CDS YP_006771506.1 410483960 13690574 complement(3972475..3973452) 1 NC_018650.1 COG0611 Thiamine monophosphate kinase; thiamine monophosphate kinase 3973452 13690574 O3M_19405 Escherichia coli O104:H4 str. 2009EL-2050 thiamine monophosphate kinase YP_006771506.1 3972475 R 1134782 CDS YP_006771507.1 410483961 13690575 complement(3973530..3973949) 1 NC_018650.1 COG0781 Transcription termination factor; transcription antitermination protein NusB 3973949 nusB 13690575 nusB Escherichia coli O104:H4 str. 2009EL-2050 transcription antitermination protein NusB YP_006771507.1 3973530 R 1134782 CDS YP_006771508.1 410483962 13690576 complement(3973969..3974439) 1 NC_018650.1 COG0054 Riboflavin synthase beta-chain; 6,7-dimethyl-8-ribityllumazine synthase 3974439 ribH 13690576 ribH Escherichia coli O104:H4 str. 2009EL-2050 6,7-dimethyl-8-ribityllumazine synthase YP_006771508.1 3973969 R 1134782 CDS YP_006771509.1 410483963 13690577 complement(3974528..3975631) 1 NC_018650.1 COG0117 Pyrimidine deaminase; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 3975631 ribD 13690577 ribD Escherichia coli O104:H4 str. 2009EL-2050 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_006771509.1 3974528 R 1134782 CDS YP_006771510.1 410483964 13690578 complement(3975635..3976084) 1 NC_018650.1 COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; transcriptional regulator NrdR 3976084 nrdR 13690578 nrdR Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator NrdR YP_006771510.1 3975635 R 1134782 CDS YP_006771511.1 410483965 13690579 3977073..3977957 1 NC_018650.1 COG3248 Nucleoside-binding outer membrane protein; nucleoside-specific channel-forming protein Tsx 3977957 13690579 O3M_19440 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside-specific channel-forming protein Tsx YP_006771511.1 3977073 D 1134782 CDS YP_006771512.1 410483966 13690580 complement(3977998..3978120) 1 NC_018650.1 hypothetical protein 3978120 13690580 O3M_19445 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771512.1 3977998 R 1134782 CDS YP_006771513.1 410483967 13690581 complement(3978134..3978481) 1 NC_018650.1 COG1403 Restriction endonuclease; hypothetical protein 3978481 13690581 O3M_19450 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771513.1 3978134 R 1134782 CDS YP_006771514.1 410483968 13690582 complement(3978610..3979581) 1 NC_018650.1 COG0341 Preprotein translocase subunit SecF; preprotein translocase subunit SecF 3979581 secF 13690582 secF Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit SecF YP_006771514.1 3978610 R 1134782 CDS YP_006771515.1 410483969 13690583 complement(3979592..3981439) 1 NC_018650.1 COG0342 Preprotein translocase subunit SecD; preprotein translocase subunit SecD 3981439 secD 13690583 secD Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit SecD YP_006771515.1 3979592 R 1134782 CDS YP_006771516.1 410483970 13690584 complement(3981467..3981799) 1 NC_018650.1 COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC 3981799 yajC 13690584 yajC Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit YajC YP_006771516.1 3981467 R 1134782 CDS YP_006771517.1 410483971 13690585 complement(3981822..3982949) 1 NC_018650.1 COG0343 Queuine/archaeosine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 3982949 tgt 13690585 tgt Escherichia coli O104:H4 str. 2009EL-2050 queuine tRNA-ribosyltransferase YP_006771517.1 3981822 R 1134782 CDS YP_006771518.1 410483972 13690586 complement(3983005..3984075) 1 NC_018650.1 COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine--tRNA ribosyltransferase-isomerase 3984075 queA 13690586 queA Escherichia coli O104:H4 str. 2009EL-2050 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_006771518.1 3983005 R 1134782 CDS YP_006771519.1 410483973 13690587 3984168..3984749 1 NC_018650.1 COG3124 Uncharacterized protein conserved in bacteria; acyl carrier protein phosphodiesterase 3984749 13690587 O3M_19480 Escherichia coli O104:H4 str. 2009EL-2050 acyl carrier protein phosphodiesterase YP_006771519.1 3984168 D 1134782 CDS YP_006771520.1 410483974 13690588 complement(3984754..3986571) 1 NC_018650.1 COG0366 Glycosidases; maltodextrin glucosidase 3986571 13690588 O3M_19485 Escherichia coli O104:H4 str. 2009EL-2050 maltodextrin glucosidase YP_006771520.1 3984754 R 1134782 CDS YP_006771521.1 410483975 13690589 complement(3986727..3988100) 1 NC_018650.1 COG1113 Gamma-aminobutyrate permease and related permeases; proline-specific permease 3988100 proY 13690589 proY Escherichia coli O104:H4 str. 2009EL-2050 proline-specific permease YP_006771521.1 3986727 R 1134782 CDS YP_006771522.1 410483976 13690590 complement(3988176..3989495) 1 NC_018650.1 COG1114 Branched-chain amino acid permeases; branched-chain amino acid transport system 2 carrier protein BrnQ 3989495 13690590 O3M_19495 Escherichia coli O104:H4 str. 2009EL-2050 branched-chain amino acid transport system 2 carrier protein BrnQ YP_006771522.1 3988176 R 1134782 CDS YP_006771523.1 410483977 13690591 complement(3989902..3991197) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; phosphate regulon sensor protein 3991197 phoR 13690591 phoR Escherichia coli O104:H4 str. 2009EL-2050 phosphate regulon sensor protein YP_006771523.1 3989902 R 1134782 CDS YP_006771524.1 410483978 13690592 complement(3991255..3991944) 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator PhoB 3991944 13690592 O3M_19505 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator PhoB YP_006771524.1 3991255 R 1134782 CDS YP_006771525.1 410483979 13690593 3992134..3993336 1 NC_018650.1 COG0420 DNA repair exonuclease; exonuclease subunit SbcD 3993336 13690593 O3M_19510 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease subunit SbcD YP_006771525.1 3992134 D 1134782 CDS YP_006771526.1 410483980 13690594 3993333..3996476 1 NC_018650.1 COG0419 ATPase involved in DNA repair; exonuclease subunit SbcC 3996476 13690594 O3M_19515 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease subunit SbcC YP_006771526.1 3993333 D 1134782 CDS YP_006771527.1 410483981 13690595 3996602..3997786 1 NC_018650.1 COG2814 Arabinose efflux permease; MFS transport protein AraJ 3997786 13690595 O3M_19520 Escherichia coli O104:H4 str. 2009EL-2050 MFS transport protein AraJ YP_006771527.1 3996602 D 1134782 CDS YP_006771528.1 410483982 13690596 complement(3997929..3998837) 1 NC_018650.1 COG1940 Transcriptional regulator/sugar kinase; fructokinase 3998837 13690596 O3M_19525 Escherichia coli O104:H4 str. 2009EL-2050 fructokinase YP_006771528.1 3997929 R 1134782 CDS YP_006771529.1 410483983 13690597 3998962..3999873 1 NC_018650.1 COG2974 DNA recombination-dependent growth factor C; exonuclease RdgC 3999873 13690597 O3M_19530 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease RdgC YP_006771529.1 3998962 D 1134782 CDS YP_006771530.1 410483984 13690598 complement(3999951..4000313) 1 NC_018650.1 hypothetical protein 4000313 13690598 O3M_19535 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771530.1 3999951 R 1134782 CDS YP_006771531.1 410483985 13690599 complement(4000574..4000858) 1 NC_018650.1 COG3123 Uncharacterized protein conserved in bacteria; hypothetical protein 4000858 13690599 O3M_19540 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771531.1 4000574 R 1134782 CDS YP_006771532.1 410483986 13690600 complement(4000930..4001607) 1 NC_018650.1 hypothetical protein 4001607 13690600 O3M_19545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771532.1 4000930 R 1134782 CDS YP_006771533.1 410483987 13690601 complement(4001865..4002056) 1 NC_018650.1 hypothetical protein 4002056 13690601 O3M_19550 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771533.1 4001865 R 1134782 CDS YP_006771534.1 410483988 13690602 complement(4002106..4002630) 1 NC_018650.1 COG0703 Shikimate kinase; shikimate kinase 4002630 aroL 13690602 aroL Escherichia coli O104:H4 str. 2009EL-2050 shikimate kinase YP_006771534.1 4002106 R 1134782 CDS YP_006771535.1 410483989 13690603 complement(4002813..4003271) 1 NC_018650.1 COG1671 Uncharacterized protein conserved in bacteria; hypothetical protein 4003271 13690603 O3M_19560 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771535.1 4002813 R 1134782 CDS YP_006771536.1 410483990 13690604 4003391..4004200 1 NC_018650.1 COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 4004200 13690604 O3M_19565 Escherichia coli O104:H4 str. 2009EL-2050 pyrroline-5-carboxylate reductase YP_006771536.1 4003391 D 1134782 CDS YP_006771537.1 410483991 13690605 complement(4004217..4005332) 1 NC_018650.1 COG2199 FOG: GGDEF domain; diguanylate cyclase AdrA 4005332 adrA 13690605 adrA Escherichia coli O104:H4 str. 2009EL-2050 diguanylate cyclase AdrA YP_006771537.1 4004217 R 1134782 CDS YP_006771538.1 410483992 13690606 complement(4005434..4005754) 1 NC_018650.1 hypothetical protein 4005754 13690606 O3M_19575 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771538.1 4005434 R 1134782 CDS YP_006771539.1 410483993 13690607 complement(4005873..4007288) 1 NC_018650.1 COG1785 Alkaline phosphatase; alkaline phosphatase 4007288 13690607 O3M_19580 Escherichia coli O104:H4 str. 2009EL-2050 alkaline phosphatase YP_006771539.1 4005873 R 1134782 CDS YP_006771540.1 410483994 13690608 complement(4007389..4007649) 1 NC_018650.1 anti-RssB factor 4007649 13690608 O3M_19585 Escherichia coli O104:H4 str. 2009EL-2050 anti-RssB factor YP_006771540.1 4007389 R 1134782 CDS YP_006771541.1 410483995 13690609 4008112..4009206 1 NC_018650.1 D-alanine-D-alanine ligase A; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanyl-alanine synthetase A 4009206 ddl 13690609 ddl Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-alanine synthetase A YP_006771541.1 4008112 D 1134782 CDS YP_006771542.1 410483996 13690610 complement(4009230..4009442) 1 NC_018650.1 hypothetical protein 4009442 13690610 O3M_19595 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771542.1 4009230 R 1134782 CDS YP_006771543.1 410483997 13690611 4009702..4010010 1 NC_018650.1 hypothetical protein 4010010 13690611 O3M_19600 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771543.1 4009702 D 1134782 CDS YP_006771544.1 410483998 13690612 complement(4010069..4011163) 1 NC_018650.1 DNA-binding transcriptional regulator 4011163 13690612 O3M_19605 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771544.1 4010069 R 1134782 CDS YP_006771545.1 410483999 13690613 complement(4011176..4012396) 1 NC_018650.1 COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components; microcin B17 transporter 4012396 13690613 O3M_19610 Escherichia coli O104:H4 str. 2009EL-2050 microcin B17 transporter YP_006771545.1 4011176 R 1134782 CDS YP_006771546.1 410484000 13690614 4012748..4013905 1 NC_018650.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactam binding protein AmpH 4013905 13690614 O3M_19615 Escherichia coli O104:H4 str. 2009EL-2050 beta-lactam binding protein AmpH YP_006771546.1 4012748 D 1134782 CDS YP_006771547.1 410484001 13690615 complement(4013906..4014529) 1 NC_018650.1 COG2186 Transcriptional regulators; DNA-binding transcriptional regulator 4014529 13690615 O3M_19620 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771547.1 4013906 R 1134782 CDS YP_006771548.1 410484002 13690616 complement(4014617..4017505) 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; flagellin structural protein 4017505 13690616 O3M_19625 Escherichia coli O104:H4 str. 2009EL-2050 flagellin structural protein YP_006771548.1 4014617 R 1134782 CDS YP_006771549.1 410484003 13690617 4018029..4019003 1 NC_018650.1 COG0113 Delta-aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase 4019003 13690617 O3M_19630 Escherichia coli O104:H4 str. 2009EL-2050 delta-aminolevulinic acid dehydratase YP_006771549.1 4018029 D 1134782 CDS YP_006771550.1 410484004 13690618 complement(4019109..4019960) 1 NC_018650.1 COG2175 Probable taurine catabolism dioxygenase; taurine dioxygenase 4019960 tauD 13690618 tauD Escherichia coli O104:H4 str. 2009EL-2050 taurine dioxygenase YP_006771550.1 4019109 R 1134782 CDS YP_006771551.1 410484005 13690619 complement(4019957..4020784) 1 NC_018650.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; taurine transporter subunit 4020784 13690619 O3M_19640 Escherichia coli O104:H4 str. 2009EL-2050 taurine transporter subunit YP_006771551.1 4019957 R 1134782 CDS YP_006771552.1 410484006 13690620 complement(4020781..4021548) 1 NC_018650.1 COG4525 ABC-type taurine transport system, ATPase component; taurine transporter ATP-binding subunit 4021548 tauB 13690620 tauB Escherichia coli O104:H4 str. 2009EL-2050 taurine transporter ATP-binding subunit YP_006771552.1 4020781 R 1134782 CDS YP_006771553.1 410484007 13690621 complement(4021561..4022523) 1 NC_018650.1 COG4521 ABC-type taurine transport system, periplasmic component; taurine transporter substrate binding subunit 4022523 tauA 13690621 tauA Escherichia coli O104:H4 str. 2009EL-2050 taurine transporter substrate binding subunit YP_006771553.1 4021561 R 1134782 CDS YP_006771554.1 410484008 13690622 4023139..4023810 1 NC_018650.1 COG2120 Uncharacterized proteins, LmbE homologs; hypothetical protein 4023810 13690622 O3M_19655 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771554.1 4023139 D 1134782 CDS YP_006771555.1 410484009 13690623 4023820..4025016 1 NC_018650.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; membrane-associated glycosyltransferase 4025016 13690623 O3M_19660 Escherichia coli O104:H4 str. 2009EL-2050 membrane-associated glycosyltransferase YP_006771555.1 4023820 D 1134782 CDS YP_006771556.1 410484010 13690624 4025135..4025575 1 NC_018650.1 COG0110 Acetyltransferase (isoleucine patch superfamily); transferase 4025575 13690624 O3M_19665 Escherichia coli O104:H4 str. 2009EL-2050 transferase YP_006771556.1 4025135 D 1134782 CDS YP_006771557.1 410484011 13690625 4025577..4026350 1 NC_018650.1 hypothetical protein 4026350 13690625 O3M_19670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771557.1 4025577 D 1134782 CDS YP_006771558.1 410484012 13690626 4026536..4026811 1 NC_018650.1 COG1937 Uncharacterized protein conserved in bacteria; regulator protein FrmR 4026811 13690626 O3M_19675 Escherichia coli O104:H4 str. 2009EL-2050 regulator protein FrmR YP_006771558.1 4026536 D 1134782 CDS YP_006771559.1 410484013 13690627 4026846..4027955 1 NC_018650.1 COG1062 Zn-dependent alcohol dehydrogenases, class III; S-(hydroxymethyl)glutathione dehydrogenase 4027955 13690627 O3M_19680 Escherichia coli O104:H4 str. 2009EL-2050 S-(hydroxymethyl)glutathione dehydrogenase YP_006771559.1 4026846 D 1134782 CDS YP_006771560.1 410484014 13690628 4028048..4028881 1 NC_018650.1 COG0627 Predicted esterase; S-formylglutathione hydrolase 4028881 13690628 O3M_19685 Escherichia coli O104:H4 str. 2009EL-2050 S-formylglutathione hydrolase YP_006771560.1 4028048 D 1134782 CDS YP_006771561.1 410484015 13690629 complement(4029108..4029647) 1 NC_018650.1 COG3122 Uncharacterized protein conserved in bacteria; nucleoprotein/polynucleotide-associated enzyme 4029647 13690629 O3M_19690 Escherichia coli O104:H4 str. 2009EL-2050 nucleoprotein/polynucleotide-associated enzyme YP_006771561.1 4029108 R 1134782 CDS YP_006771562.1 410484016 13690630 complement(4029749..4030960) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; 3-hydroxyphenylpropionic transporter MhpT 4030960 13690630 O3M_19695 Escherichia coli O104:H4 str. 2009EL-2050 3-hydroxyphenylpropionic transporter MhpT YP_006771562.1 4029749 R 1134782 CDS YP_006771563.1 410484017 13690631 complement(4031136..4032149) 1 NC_018650.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase 4032149 13690631 O3M_19700 Escherichia coli O104:H4 str. 2009EL-2050 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase YP_006771563.1 4031136 R 1134782 CDS YP_006771564.1 410484018 13690632 complement(4032146..4033096) 1 NC_018650.1 COG4569 Acetaldehyde dehydrogenase (acetylating); acetaldehyde dehydrogenase 4033096 13690632 O3M_19705 Escherichia coli O104:H4 str. 2009EL-2050 acetaldehyde dehydrogenase YP_006771564.1 4032146 R 1134782 CDS YP_006771565.1 410484019 13690633 complement(4033093..4033902) 1 NC_018650.1 COG3971 2-keto-4-pentenoate hydratase; 2-keto-4-pentenoate hydratase 4033902 mhpD 13690633 mhpD Escherichia coli O104:H4 str. 2009EL-2050 2-keto-4-pentenoate hydratase YP_006771565.1 4033093 R 1134782 CDS YP_006771566.1 410484020 13690634 complement(4033912..4034793) 1 NC_018650.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 4034793 13690634 O3M_19715 Escherichia coli O104:H4 str. 2009EL-2050 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_006771566.1 4033912 R 1134782 CDS YP_006771567.1 410484021 13690635 complement(4034796..4035740) 1 NC_018650.1 3-(2,3-dihydroxyphenyl)propionate dioxygenase 4035740 mhpB 13690635 mhpB Escherichia coli O104:H4 str. 2009EL-2050 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_006771567.1 4034796 R 1134782 CDS YP_006771568.1 410484022 13690636 complement(4035742..4037406) 1 NC_018650.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 3-(3-hydroxyphenyl)propionate hydroxylase 4037406 mhpA 13690636 mhpA Escherichia coli O104:H4 str. 2009EL-2050 3-(3-hydroxyphenyl)propionate hydroxylase YP_006771568.1 4035742 R 1134782 CDS YP_006771569.1 410484023 13690637 4037483..4038430 1 NC_018650.1 COG1414 Transcriptional regulator; DNA-binding transcriptional activator MhpR 4038430 13690637 O3M_19730 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator MhpR YP_006771569.1 4037483 D 1134782 CDS YP_006771570.1 410484024 13690638 4038507..4039589 1 NC_018650.1 COG1609 Transcriptional regulators; lac repressor 4039589 lacI 13690638 lacI Escherichia coli O104:H4 str. 2009EL-2050 lac repressor YP_006771570.1 4038507 D 1134782 CDS YP_006771571.1 410484025 13690639 4039712..4042786 1 NC_018650.1 COG3250 Beta-galactosidase/beta-glucuronidase; beta-D-galactosidase 4042786 lacZ 13690639 lacZ Escherichia coli O104:H4 str. 2009EL-2050 beta-D-galactosidase YP_006771571.1 4039712 D 1134782 CDS YP_006771572.1 410484026 13690640 4042838..4044091 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; galactoside permease 4044091 lacY 13690640 lacY Escherichia coli O104:H4 str. 2009EL-2050 galactoside permease YP_006771572.1 4042838 D 1134782 CDS YP_006771573.1 410484027 13690641 4044157..4044768 1 NC_018650.1 COG0110 Acetyltransferase (isoleucine patch superfamily); galactoside O-acetyltransferase 4044768 lacA 13690641 lacA Escherichia coli O104:H4 str. 2009EL-2050 galactoside O-acetyltransferase YP_006771573.1 4044157 D 1134782 CDS YP_006771574.1 410484028 13690642 complement(4044871..4046025) 1 NC_018650.1 COG2807 Cyanate permease; cyanate transporter 4046025 cynX 13690642 cynX Escherichia coli O104:H4 str. 2009EL-2050 cyanate transporter YP_006771574.1 4044871 R 1134782 CDS YP_006771575.1 410484029 13690643 complement(4046058..4046528) 1 NC_018650.1 COG1513 Cyanate lyase; cyanate hydratase 4046528 13690643 O3M_19760 Escherichia coli O104:H4 str. 2009EL-2050 cyanate hydratase YP_006771575.1 4046058 R 1134782 CDS YP_006771576.1 410484030 13690644 complement(4046559..4047218) 1 NC_018650.1 COG0288 Carbonic anhydrase; carbonate dehydratase 4047218 13690644 O3M_19765 Escherichia coli O104:H4 str. 2009EL-2050 carbonate dehydratase YP_006771576.1 4046559 R 1134782 CDS YP_006771577.1 410484031 13690645 4047328..4048227 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator CynR 4048227 13690645 O3M_19770 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator CynR YP_006771577.1 4047328 D 1134782 CDS YP_006771578.1 410484032 13690646 complement(4048267..4049550) 1 NC_018650.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; cytosine deaminase 4049550 13690646 O3M_19775 Escherichia coli O104:H4 str. 2009EL-2050 cytosine deaminase YP_006771578.1 4048267 R 1134782 CDS YP_006771579.1 410484033 13690647 complement(4049540..4050799) 1 NC_018650.1 COG1457 Purine-cytosine permease and related proteins; cytosine permease 4050799 codB 13690647 codB Escherichia coli O104:H4 str. 2009EL-2050 cytosine permease YP_006771579.1 4049540 R 1134782 CDS YP_006771580.1 410484034 13690648 complement(4051225..4053111) 1 NC_018650.1 COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; propionyl-CoA synthetase 4053111 prpE 13690648 prpE Escherichia coli O104:H4 str. 2009EL-2050 propionyl-CoA synthetase YP_006771580.1 4051225 R 1134782 CDS YP_006771581.1 410484035 13690649 complement(4053151..4054602) 1 NC_018650.1 COG2079 Uncharacterized protein involved in propionate catabolism; 2-methylcitrate dehydratase 4054602 prpD 13690649 prpD Escherichia coli O104:H4 str. 2009EL-2050 2-methylcitrate dehydratase YP_006771581.1 4053151 R 1134782 CDS YP_006771582.1 410484036 13690650 complement(4054636..4055805) 1 NC_018650.1 COG0372 Citrate synthase; methylcitrate synthase 4055805 13690650 O3M_19795 Escherichia coli O104:H4 str. 2009EL-2050 methylcitrate synthase YP_006771582.1 4054636 R 1134782 CDS YP_006771583.1 410484037 13690651 complement(4055850..4056740) 1 NC_018650.1 COG2513 PEP phosphonomutase and related enzymes; 2-methylisocitrate lyase 4056740 prpB 13690651 prpB Escherichia coli O104:H4 str. 2009EL-2050 2-methylisocitrate lyase YP_006771583.1 4055850 R 1134782 CDS YP_006771584.1 410484038 13690652 4056978..4058564 1 NC_018650.1 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains; propionate catabolism operon regulatory protein PrpR 4058564 13690652 O3M_19805 Escherichia coli O104:H4 str. 2009EL-2050 propionate catabolism operon regulatory protein PrpR YP_006771584.1 4056978 D 1134782 CDS YP_006771585.1 410484039 13690653 complement(4058665..4058940) 1 NC_018650.1 hypothetical protein 4058940 13690653 O3M_19810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771585.1 4058665 R 1134782 CDS YP_006771586.1 410484040 13690654 4059126..4059758 1 NC_018650.1 COG1280 Putative threonine efflux protein; neutral amino-acid efflux system 4059758 13690654 O3M_19815 Escherichia coli O104:H4 str. 2009EL-2050 neutral amino-acid efflux system YP_006771586.1 4059126 D 1134782 CDS YP_006771587.1 410484041 13690655 complement(4059775..4060020) 1 NC_018650.1 hypothetical protein 4060020 13690655 O3M_19820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771587.1 4059775 R 1134782 CDS YP_006771588.1 410484042 13690657 complement(4060432..4061247) 1 NC_018650.1 hypothetical protein 4061247 13690657 O3M_19825 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771588.1 4060432 R 1134782 CDS YP_006771589.1 410484043 13690658 complement(4061490..4062539) 1 NC_018650.1 COG1064 Zn-dependent alcohol dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein 4062539 13690658 O3M_19830 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase, Zn-dependent and NAD(P)-binding protein YP_006771589.1 4061490 R 1134782 CDS YP_006771590.1 410484044 13690659 complement(4062626..4063582) 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease 4063582 13690659 O3M_19835 Escherichia coli O104:H4 str. 2009EL-2050 sugar ABC transporter permease YP_006771590.1 4062626 R 1134782 CDS YP_006771591.1 410484045 13690660 complement(4063579..4064550) 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; permease of transporter probably ribose specific 4064550 13690660 O3M_19840 Escherichia coli O104:H4 str. 2009EL-2050 permease of transporter probably ribose specific YP_006771591.1 4063579 R 1134782 CDS YP_006771592.1 410484046 13690661 complement(4064543..4066027) 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein 4066027 13690661 O3M_19845 Escherichia coli O104:H4 str. 2009EL-2050 sugar ABC transporter ATP-binding protein YP_006771592.1 4064543 R 1134782 CDS YP_006771593.1 410484047 13690662 complement(4066076..4067062) 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; sugar-binding protein 4067062 13690662 O3M_19850 Escherichia coli O104:H4 str. 2009EL-2050 sugar-binding protein YP_006771593.1 4066076 R 1134782 CDS YP_006771594.1 410484048 13690663 complement(4067313..4067753) 1 NC_018650.1 COG4405 Uncharacterized protein conserved in bacteria; hypothetical protein 4067753 13690663 O3M_19855 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771594.1 4067313 R 1134782 CDS YP_006771595.1 410484049 13690664 complement(4068022..4069404) 1 NC_018650.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; deaminase 4069404 13690664 O3M_19860 Escherichia coli O104:H4 str. 2009EL-2050 deaminase YP_006771595.1 4068022 R 1134782 CDS YP_006771596.1 410484050 13690665 complement(4069414..4070364) 1 NC_018650.1 COG0549 Carbamate kinase; carbamate kinase 4070364 13690665 O3M_19865 Escherichia coli O104:H4 str. 2009EL-2050 carbamate kinase YP_006771596.1 4069414 R 1134782 CDS YP_006771597.1 410484051 13690666 complement(4070507..4071925) 1 NC_018650.1 hypothetical protein 4071925 13690666 O3M_19870 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771597.1 4070507 R 1134782 CDS YP_006771598.1 410484052 13690667 complement(4071925..4073472) 1 NC_018650.1 COG0074 Succinyl-CoA synthetase, alpha subunit; enzyme with acyl-CoA domain 4073472 13690667 O3M_19875 Escherichia coli O104:H4 str. 2009EL-2050 enzyme with acyl-CoA domain YP_006771598.1 4071925 R 1134782 CDS YP_006771599.1 410484053 13690668 complement(4073462..4074325) 1 NC_018650.1 hypothetical protein 4074325 13690668 O3M_19880 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771599.1 4073462 R 1134782 CDS YP_006771600.1 410484054 13690669 complement(4074365..4074970) 1 NC_018650.1 COG0666 FOG: Ankyrin repeat; transcriptional regulator 4074970 13690669 O3M_19885 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006771600.1 4074365 R 1134782 CDS YP_006771601.1 410484055 13690670 4075228..4075725 1 NC_018650.1 inner membrane protein 4075725 13690670 O3M_19890 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771601.1 4075228 D 1134782 CDS YP_006771602.1 410484056 13690671 4075817..4076749 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 4076749 13690671 O3M_19895 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006771602.1 4075817 D 1134782 CDS YP_006771603.1 410484057 13690672 complement(4076791..4077879) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional regulator 4077879 13690672 O3M_19900 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771603.1 4076791 R 1134782 CDS YP_006771604.1 410484058 13690673 complement(4078021..4082004) 1 NC_018650.1 COG5295 Autotransporter adhesin; AidA-I adhesin-like protein 4082004 13690673 O3M_19905 Escherichia coli O104:H4 str. 2009EL-2050 AidA-I adhesin-like protein YP_006771604.1 4078021 R 1134782 CDS YP_006771605.1 410484059 13690674 complement(4082577..4084610) 1 NC_018650.1 COG1292 Choline-glycine betaine transporter; choline transport protein BetT 4084610 13690674 O3M_19910 Escherichia coli O104:H4 str. 2009EL-2050 choline transport protein BetT YP_006771605.1 4082577 R 1134782 CDS YP_006771606.1 410484060 13690675 4084739..4085326 1 NC_018650.1 COG1309 Transcriptional regulator; transcriptional regulator BetI 4085326 13690675 O3M_19915 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator BetI YP_006771606.1 4084739 D 1134782 CDS YP_006771607.1 410484061 13690676 4085340..4086812 1 NC_018650.1 COG1012 NAD-dependent aldehyde dehydrogenases; betaine aldehyde dehydrogenase 4086812 13690676 O3M_19920 Escherichia coli O104:H4 str. 2009EL-2050 betaine aldehyde dehydrogenase YP_006771607.1 4085340 D 1134782 CDS YP_006771608.1 410484062 13690677 4086826..4088496 1 NC_018650.1 COG2303 Choline dehydrogenase and related flavoproteins; choline dehydrogenase 4088496 13690677 O3M_19925 Escherichia coli O104:H4 str. 2009EL-2050 choline dehydrogenase YP_006771608.1 4086826 D 1134782 CDS YP_006771609.1 410484063 13690678 4088709..4089374 1 NC_018650.1 inner membrane protein 4089374 13690678 O3M_19930 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771609.1 4088709 D 1134782 CDS YP_006771610.1 410484064 13690679 complement(4089620..4090315) 1 NC_018650.1 COG1556 Uncharacterized conserved protein; hypothetical protein 4090315 13690679 O3M_19935 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771610.1 4089620 R 1134782 CDS YP_006771611.1 410484065 13690680 complement(4090308..4091735) 1 NC_018650.1 oxidoreductase subunit with NAD(P)-binding domain and ferridoxin-like domain; COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain; iron-sulfur cluster binding protein 4091735 13690680 O3M_19940 Escherichia coli O104:H4 str. 2009EL-2050 iron-sulfur cluster binding protein YP_006771611.1 4090308 R 1134782 CDS YP_006771612.1 410484066 13690681 complement(4091746..4092465) 1 NC_018650.1 COG0247 Fe-S oxidoreductase; oxidoreductase 4092465 13690681 O3M_19945 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006771612.1 4091746 R 1134782 CDS YP_006771613.1 410484067 13690682 complement(4092992..4093846) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator, ARAC-type 4093846 13690682 O3M_19950 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator, ARAC-type YP_006771613.1 4092992 R 1134782 CDS YP_006771614.1 410484068 13690683 4094072..4095397 1 NC_018650.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyridine nucleotide-disulfide oxidoreductase 4095397 13690683 O3M_19955 Escherichia coli O104:H4 str. 2009EL-2050 pyridine nucleotide-disulfide oxidoreductase YP_006771614.1 4094072 D 1134782 CDS YP_006771615.1 410484069 13690684 4095506..4095742 1 NC_018650.1 hypothetical protein 4095742 13690684 O3M_19960 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771615.1 4095506 D 1134782 CDS YP_006771616.1 410484070 13690685 4095754..4096182 1 NC_018650.1 COG3059 Predicted membrane protein; hypothetical protein 4096182 13690685 O3M_19965 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771616.1 4095754 D 1134782 CDS YP_006771617.1 410484071 13690686 complement(4096220..4097200) 1 NC_018650.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 4097200 13690686 O3M_19970 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771617.1 4096220 R 1134782 CDS YP_006771618.1 410484072 13690687 4097199..4097546 1 NC_018650.1 COG3059 Predicted membrane protein; hypothetical protein 4097546 13690687 O3M_19975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771618.1 4097199 D 1134782 CDS YP_006771619.1 410484073 13690688 4098136..4098993 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; Putative transcriptional regulator ykgA 4098993 13690688 O3M_19980 Escherichia coli O104:H4 str. 2009EL-2050 Putative transcriptional regulator ykgA YP_006771619.1 4098136 D 1134782 CDS YP_006771620.1 410484074 13690689 complement(4099114..4103367) 1 NC_018650.1 adhesin 4103367 13690689 O3M_19985 Escherichia coli O104:H4 str. 2009EL-2050 adhesin YP_006771620.1 4099114 R 1134782 CDS YP_006771621.1 410484075 13690690 4104483..4104584 1 NC_018650.1 hypothetical protein 4104584 13690690 O3M_19990 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771621.1 4104483 D 1134782 CDS YP_006771622.1 410484076 13690691 4104948..4105211 1 NC_018650.1 COG0254 Ribosomal protein L31; 50S ribosomal protein L31 4105211 rpmE2 13690691 rpmE2 Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L31 YP_006771622.1 4104948 D 1134782 CDS YP_006771623.1 410484077 13690692 4105211..4105351 1 NC_018650.1 COG0257 Ribosomal protein L36; 50S ribosomal protein L36 4105351 rpmJ 13690692 rpmJ Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L36 YP_006771623.1 4105211 D 1134782 CDS YP_006771624.1 410484078 13690693 complement(4105386..4105613) 1 NC_018650.1 hypothetical protein 4105613 13690693 O3M_20005 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771624.1 4105386 R 1134782 CDS YP_006771625.1 410484079 13690694 4106388..4106978 1 NC_018650.1 COG2771 DNA-binding HTH domain-containing proteins; transcriptional regulator 4106978 13690694 O3M_20010 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006771625.1 4106388 D 1134782 CDS YP_006771626.1 410484080 13690695 4107053..4107640 1 NC_018650.1 hypothetical protein 4107640 13690695 O3M_20015 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771626.1 4107053 D 1134782 CDS YP_006771627.1 410484081 13690696 4107698..4108366 1 NC_018650.1 chaperone 4108366 13690696 O3M_20020 Escherichia coli O104:H4 str. 2009EL-2050 chaperone YP_006771627.1 4107698 D 1134782 CDS YP_006771628.1 410484082 13690697 4108392..4110917 1 NC_018650.1 hypothetical protein 4110917 13690697 O3M_20025 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771628.1 4108392 D 1134782 CDS YP_006771629.1 410484083 13690698 4110907..4112550 1 NC_018650.1 hypothetical protein 4112550 13690698 O3M_20030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771629.1 4110907 D 1134782 CDS YP_006771630.1 410484084 13690699 4112519..4113229 1 NC_018650.1 hypothetical protein 4113229 13690699 O3M_20035 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771630.1 4112519 D 1134782 CDS YP_006771631.1 410484085 13690700 4113542..4113871 1 NC_018650.1 COG0727 Predicted Fe-S-cluster oxidoreductase; ferredoxin 4113871 13690700 O3M_20040 Escherichia coli O104:H4 str. 2009EL-2050 ferredoxin YP_006771631.1 4113542 D 1134782 CDS YP_006771632.1 410484086 13690701 complement(4114119..4114733) 1 NC_018650.1 COG3477 Predicted periplasmic/secreted protein; hypothetical protein 4114733 13690701 O3M_20045 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771632.1 4114119 R 1134782 CDS YP_006771633.1 410484087 13690702 4115151..4115840 1 NC_018650.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; aldehyde oxidoreductase 2Fe-2S subunit 4115840 13690702 O3M_20050 Escherichia coli O104:H4 str. 2009EL-2050 aldehyde oxidoreductase 2Fe-2S subunit YP_006771633.1 4115151 D 1134782 CDS YP_006771634.1 410484088 13690703 4115837..4116793 1 NC_018650.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; oxidoreductase 4116793 13690703 O3M_20055 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006771634.1 4115837 D 1134782 CDS YP_006771635.1 410484089 13690704 4116790..4118988 1 NC_018650.1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; oxidoreductase with molybdenum-binding domain 4118988 13690704 O3M_20060 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase with molybdenum-binding domain YP_006771635.1 4116790 D 1134782 CDS YP_006771636.1 410484090 13690705 4118998..4119954 1 NC_018650.1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 4119954 13690705 O3M_20065 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771636.1 4118998 D 1134782 CDS YP_006771637.1 410484091 13690706 4119933..4120343 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional regulator 4120343 13690706 O3M_20070 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006771637.1 4119933 D 1134782 CDS YP_006771638.1 410484092 13690707 4120630..4121907 1 NC_018650.1 COG0582 Integrase; integrase 4121907 13690707 O3M_20075 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006771638.1 4120630 D 1134782 CDS YP_006771639.1 410484093 13690708 complement(4121988..4122299) 1 NC_018650.1 hypothetical protein 4122299 13690708 O3M_20080 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771639.1 4121988 R 1134782 CDS YP_006771640.1 410484094 13690709 4122353..4123333 1 NC_018650.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 4123333 13690709 O3M_20085 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771640.1 4122353 D 1134782 CDS YP_006771641.1 410484095 13690710 complement(4123442..4123864) 1 NC_018650.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 4123864 13690710 O3M_20090 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771641.1 4123442 R 1134782 CDS YP_006771642.1 410484096 13690711 complement(4123912..4125753) 1 NC_018650.1 hypothetical protein 4125753 13690711 O3M_20095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771642.1 4123912 R 1134782 CDS YP_006771643.1 410484097 13690712 complement(4126137..4127168) 1 NC_018650.1 hypothetical protein 4127168 13690712 O3M_20100 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771643.1 4126137 R 1134782 CDS YP_006771644.1 410484098 13690713 complement(4127183..4127566) 1 NC_018650.1 hypothetical protein 4127566 13690713 O3M_20105 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771644.1 4127183 R 1134782 CDS YP_006771645.1 410484099 13690714 complement(4127571..4127768) 1 NC_018650.1 hypothetical protein 4127768 13690714 O3M_20110 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771645.1 4127571 R 1134782 CDS YP_006771646.1 410484100 13690715 complement(4128759..4129058) 1 NC_018650.1 hypothetical protein 4129058 13690715 O3M_20115 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771646.1 4128759 R 1134782 CDS YP_006771647.1 410484101 13690716 complement(4129058..4129261) 1 NC_018650.1 hypothetical protein 4129261 13690716 O3M_20120 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771647.1 4129058 R 1134782 CDS YP_006771648.1 410484102 13690717 complement(4129319..4129702) 1 NC_018650.1 hypothetical protein 4129702 13690717 O3M_20125 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771648.1 4129319 R 1134782 CDS YP_006771649.1 410484103 13690718 complement(4129800..4130069) 1 NC_018650.1 hypothetical protein 4130069 13690718 O3M_20130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771649.1 4129800 R 1134782 CDS YP_006771650.1 410484104 13690719 complement(4130079..4130747) 1 NC_018650.1 hypothetical protein 4130747 13690719 O3M_20135 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771650.1 4130079 R 1134782 CDS YP_006771651.1 410484105 13690720 4132752..4133303 1 NC_018650.1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; resolvase domain-containing protein 4133303 13690720 O3M_20140 Escherichia coli O104:H4 str. 2009EL-2050 resolvase domain-containing protein YP_006771651.1 4132752 D 1134782 CDS YP_006771652.1 410484106 13690721 complement(4133869..4134021) 1 NC_018650.1 hypothetical protein 4134021 13690721 O3M_20145 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771652.1 4133869 R 1134782 CDS YP_006771653.1 410484107 13690723 complement(4134818..4136071) 1 NC_018650.1 COG0014 Gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase 4136071 proA 13690723 proA Escherichia coli O104:H4 str. 2009EL-2050 gamma-glutamyl phosphate reductase YP_006771653.1 4134818 R 1134782 CDS YP_006771654.1 410484108 13690724 complement(4136083..4137186) 1 NC_018650.1 COG0263 Glutamate 5-kinase; gamma-glutamyl kinase 4137186 13690724 O3M_20155 Escherichia coli O104:H4 str. 2009EL-2050 gamma-glutamyl kinase YP_006771654.1 4136083 R 1134782 CDS YP_006771655.1 410484109 13690725 4137474..4138529 1 NC_018650.1 COG3203 Outer membrane protein (porin); outer membrane phosphoporin protein E 4138529 13690725 O3M_20160 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane phosphoporin protein E YP_006771655.1 4137474 D 1134782 CDS YP_006771656.1 410484110 13690726 complement(4138568..4138969) 1 NC_018650.1 DNA-binding transcriptional regulator Crl 4138969 13690726 O3M_20165 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator Crl YP_006771656.1 4138568 R 1134782 CDS YP_006771657.1 410484111 13690727 complement(4139027..4140271) 1 NC_018650.1 COG1073 Hydrolases of the alpha/beta superfamily; fermentation/respiration switch protein 4140271 frsA 13690727 frsA Escherichia coli O104:H4 str. 2009EL-2050 fermentation/respiration switch protein YP_006771657.1 4139027 R 1134782 CDS YP_006771658.1 410484112 13690728 complement(4140363..4140821) 1 NC_018650.1 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; xanthine-guanine phosphoribosyltransferase 4140821 13690728 O3M_20175 Escherichia coli O104:H4 str. 2009EL-2050 xanthine-guanine phosphoribosyltransferase YP_006771658.1 4140363 R 1134782 CDS YP_006771659.1 410484113 13690729 4141082..4142539 1 NC_018650.1 COG2195 Di- and tripeptidases; aminoacyl-histidine dipeptidase 4142539 13690729 O3M_20180 Escherichia coli O104:H4 str. 2009EL-2050 aminoacyl-histidine dipeptidase YP_006771659.1 4141082 D 1134782 CDS YP_006771660.1 410484114 13690730 complement(4142596..4143210) 1 NC_018650.1 COG1186 Protein chain release factor B; peptide chain release factor-like protein 4143210 prfH 13690730 prfH Escherichia coli O104:H4 str. 2009EL-2050 peptide chain release factor-like protein YP_006771660.1 4142596 R 1134782 CDS YP_006771661.1 410484115 13690731 complement(4143207..4144346) 1 NC_018650.1 COG1690 Uncharacterized conserved protein; hypothetical protein 4144346 13690731 O3M_20190 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771661.1 4143207 R 1134782 CDS YP_006771662.1 410484116 13690732 complement(4144592..4145044) 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acyltransferase 4145044 13690732 O3M_20195 Escherichia coli O104:H4 str. 2009EL-2050 acyltransferase YP_006771662.1 4144592 R 1134782 CDS YP_006771663.1 410484117 13690733 complement(4145041..4146096) 1 NC_018650.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase IV 4146096 13690733 O3M_20200 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase IV YP_006771663.1 4145041 R 1134782 CDS YP_006771664.1 410484118 13690734 complement(4146167..4146952) 1 NC_018650.1 COG1360 Flagellar motor protein; hypothetical protein 4146952 13690734 O3M_20205 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771664.1 4146167 R 1134782 CDS YP_006771665.1 410484119 13690735 4146897..4148636 1 NC_018650.1 COG1298 Flagellar biosynthesis pathway, component FlhA; flagellar system protein 4148636 13690735 O3M_20210 Escherichia coli O104:H4 str. 2009EL-2050 flagellar system protein YP_006771665.1 4146897 D 1134782 CDS YP_006771666.1 410484120 13690736 4148741..4149019 1 NC_018650.1 hypothetical protein 4149019 13690736 O3M_20215 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771666.1 4148741 D 1134782 CDS YP_006771667.1 410484121 13690737 4149012..4149368 1 NC_018650.1 COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters; HicB protein 4149368 13690737 O3M_20220 Escherichia coli O104:H4 str. 2009EL-2050 HicB protein YP_006771667.1 4149012 D 1134782 CDS YP_006771668.1 410484122 13690738 complement(4149425..4150174) 1 NC_018650.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hydrolase 4150174 13690738 O3M_20225 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006771668.1 4149425 R 1134782 CDS YP_006771669.1 410484123 13690739 4150384..4150644 1 NC_018650.1 COG3077 DNA-damage-inducible protein J; DNA-damage-inducible protein J 4150644 13690739 O3M_20230 Escherichia coli O104:H4 str. 2009EL-2050 DNA-damage-inducible protein J YP_006771669.1 4150384 D 1134782 CDS YP_006771670.1 410484124 13690740 4150647..4150925 1 NC_018650.1 COG3041 Uncharacterized protein conserved in bacteria; toxin of the YafQ-DinJ toxin-antitoxin system 4150925 13690740 O3M_20235 Escherichia coli O104:H4 str. 2009EL-2050 toxin of the YafQ-DinJ toxin-antitoxin system YP_006771670.1 4150647 D 1134782 CDS YP_006771671.1 410484125 13690741 4151081..4151821 1 NC_018650.1 COG3034 Uncharacterized protein conserved in bacteria; hypothetical protein 4151821 13690741 O3M_20240 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771671.1 4151081 D 1134782 CDS YP_006771672.1 410484126 13690742 complement(4151792..4152559) 1 NC_018650.1 COG0121 Predicted glutamine amidotransferase; amidotransferase 4152559 13690742 O3M_20245 Escherichia coli O104:H4 str. 2009EL-2050 amidotransferase YP_006771672.1 4151792 R 1134782 CDS YP_006771673.1 410484127 13690743 complement(4152765..4153343) 1 NC_018650.1 COG0279 Phosphoheptose isomerase; phosphoheptose isomerase 4153343 gmhA 13690743 gmhA Escherichia coli O104:H4 str. 2009EL-2050 phosphoheptose isomerase YP_006771673.1 4152765 R 1134782 CDS YP_006771674.1 410484128 13690744 4153583..4156027 1 NC_018650.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 4156027 fadE 13690744 fadE Escherichia coli O104:H4 str. 2009EL-2050 acyl-CoA dehydrogenase YP_006771674.1 4153583 D 1134782 CDS YP_006771675.1 410484129 13690745 complement(4156070..4156543) 1 NC_018650.1 C-lysozyme inhibitor 4156543 13690745 O3M_20260 Escherichia coli O104:H4 str. 2009EL-2050 C-lysozyme inhibitor YP_006771675.1 4156070 R 1134782 CDS YP_006771676.1 410484130 13690746 4156697..4157467 1 NC_018650.1 COG0388 Predicted amidohydrolase; C-N hydrolase family amidase 4157467 13690746 O3M_20265 Escherichia coli O104:H4 str. 2009EL-2050 C-N hydrolase family amidase YP_006771676.1 4156697 D 1134782 CDS YP_006771677.1 410484131 13690747 complement(4157509..4158570) 1 NC_018650.1 COG5433 Transposase; transposase 4158570 13690747 O3M_20270 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771677.1 4157509 R 1134782 CDS YP_006771678.1 410484132 13690748 complement(4160055..4160537) 1 NC_018650.1 hypothetical protein 4160537 13690748 O3M_20285 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771678.1 4160055 R 1134782 CDS YP_006771679.1 410484133 13690749 complement(4160521..4161711) 1 NC_018650.1 COG3209 Rhs family protein; Rhs Core protein 4161711 13690749 O3M_20290 Escherichia coli O104:H4 str. 2009EL-2050 Rhs Core protein YP_006771679.1 4160521 R 1134782 CDS YP_006771680.1 410484134 13690750 complement(4161680..4164184) 1 NC_018650.1 COG3209 Rhs family protein; Rhs core protein 4164184 13690750 O3M_20295 Escherichia coli O104:H4 str. 2009EL-2050 Rhs core protein YP_006771680.1 4161680 R 1134782 CDS YP_006771681.1 410484135 13690751 complement(4164260..4166401) 1 NC_018650.1 COG3501 Uncharacterized protein conserved in bacteria; hypothetical protein 4166401 13690751 O3M_20300 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771681.1 4164260 R 1134782 CDS YP_006771682.1 410484136 13690752 complement(4166611..4167129) 1 NC_018650.1 COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein 4167129 13690752 O3M_20305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771682.1 4166611 R 1134782 CDS YP_006771683.1 410484137 13690753 complement(4167256..4167399) 1 NC_018650.1 hypothetical protein 4167399 13690753 O3M_20310 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771683.1 4167256 R 1134782 CDS YP_006771684.1 410484138 13690754 4167826..4168326 1 NC_018650.1 COG3516 Uncharacterized protein conserved in bacteria; hypothetical protein 4168326 13690754 O3M_20315 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771684.1 4167826 D 1134782 CDS YP_006771685.1 410484139 13690755 4168361..4168585 1 NC_018650.1 COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 4168585 13690755 O3M_20320 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771685.1 4168361 D 1134782 CDS YP_006771686.1 410484140 13690756 4168636..4170111 1 NC_018650.1 COG3517 Uncharacterized protein conserved in bacteria; hypothetical protein 4170111 13690756 O3M_20325 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771686.1 4168636 D 1134782 CDS YP_006771687.1 410484141 13690757 4170118..4170531 1 NC_018650.1 COG3518 Uncharacterized protein conserved in bacteria; hypothetical protein 4170531 13690757 O3M_20330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771687.1 4170118 D 1134782 CDS YP_006771688.1 410484142 13690758 4170535..4172385 1 NC_018650.1 COG3519 Uncharacterized protein conserved in bacteria; type VI secretion system protein ImpG 4172385 13690758 O3M_20335 Escherichia coli O104:H4 str. 2009EL-2050 type VI secretion system protein ImpG YP_006771688.1 4170535 D 1134782 CDS YP_006771689.1 410484143 13690759 4172349..4173431 1 NC_018650.1 COG3520 Uncharacterized protein conserved in bacteria; hypothetical protein 4173431 13690759 O3M_20340 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771689.1 4172349 D 1134782 CDS YP_006771690.1 410484144 13690760 4173456..4174736 1 NC_018650.1 COG3456 Uncharacterized conserved protein, contains FHA domain; type VI secretion system protein ImpI 4174736 13690760 O3M_20345 Escherichia coli O104:H4 str. 2009EL-2050 type VI secretion system protein ImpI YP_006771690.1 4173456 D 1134782 CDS YP_006771691.1 410484145 13690761 4174733..4175257 1 NC_018650.1 COG3521 Uncharacterized protein conserved in bacteria; lipoprotein 4175257 13690761 O3M_20350 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006771691.1 4174733 D 1134782 CDS YP_006771692.1 410484146 13690762 4175260..4176591 1 NC_018650.1 COG3522 Uncharacterized protein conserved in bacteria; hypothetical protein 4176591 13690762 O3M_20355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771692.1 4175260 D 1134782 CDS YP_006771693.1 410484147 13690763 4176596..4177357 1 NC_018650.1 COG3455 Uncharacterized protein conserved in bacteria; membrane protein Aec26 4177357 13690763 O3M_20360 Escherichia coli O104:H4 str. 2009EL-2050 membrane protein Aec26 YP_006771693.1 4176596 D 1134782 CDS YP_006771694.1 410484148 13690764 4177366..4180125 1 NC_018650.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp proteinase ATP-binding subunit 4180125 13690764 O3M_20365 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent Clp proteinase ATP-binding subunit YP_006771694.1 4177366 D 1134782 CDS YP_006771695.1 410484149 13690765 4180122..4180865 1 NC_018650.1 hypothetical protein 4180865 13690765 O3M_20370 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771695.1 4180122 D 1134782 CDS YP_006771696.1 410484150 13690766 4180870..4182285 1 NC_018650.1 COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 4182285 13690766 O3M_20375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771696.1 4180870 D 1134782 CDS YP_006771697.1 410484151 13690767 4182304..4185828 1 NC_018650.1 COG3523 Uncharacterized protein conserved in bacteria; IcmF-like protein 4185828 13690767 O3M_20380 Escherichia coli O104:H4 str. 2009EL-2050 IcmF-like protein YP_006771697.1 4182304 D 1134782 CDS YP_006771698.1 410484152 13690768 4185839..4187191 1 NC_018650.1 COG3515 Uncharacterized protein conserved in bacteria; hypothetical protein 4187191 13690768 O3M_20385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771698.1 4185839 D 1134782 CDS YP_006771699.1 410484153 13690769 4187215..4187697 1 NC_018650.1 COG3157 Hemolysin-coregulated protein (uncharacterized); hypothetical protein 4187697 13690769 O3M_20390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771699.1 4187215 D 1134782 CDS YP_006771700.1 410484154 13690770 4187741..4188655 1 NC_018650.1 hypothetical protein 4188655 13690770 O3M_20395 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771700.1 4187741 D 1134782 CDS YP_006771701.1 410484155 13690771 4188665..4189144 1 NC_018650.1 hypothetical protein 4189144 13690771 O3M_20400 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771701.1 4188665 D 1134782 CDS YP_006771702.1 410484156 13690772 complement(4189281..4190066) 1 NC_018650.1 aminopeptidase 4190066 13690772 O3M_20405 Escherichia coli O104:H4 str. 2009EL-2050 aminopeptidase YP_006771702.1 4189281 R 1134782 CDS YP_006771703.1 410484157 13690774 complement(4190602..4191333) 1 NC_018650.1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; DNA polymerase III subunit epsilon 4191333 13690774 O3M_20410 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit epsilon YP_006771703.1 4190602 R 1134782 CDS YP_006771704.1 410484158 13690775 4191398..4191865 1 NC_018650.1 COG0328 Ribonuclease HI; ribonuclease H 4191865 rnhA 13690775 rnhA Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease H YP_006771704.1 4191398 D 1134782 CDS YP_006771705.1 410484159 13690776 complement(4191862..4192584) 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase 4192584 13690776 O3M_20420 Escherichia coli O104:H4 str. 2009EL-2050 S-adenosyl-L-methionine-dependent methyltransferase YP_006771705.1 4191862 R 1134782 CDS YP_006771706.1 410484160 13690777 4192618..4193373 1 NC_018650.1 COG0491 Zn-dependent hydrolases, including glyoxylases; hydroxyacylglutathione hydrolase 4193373 13690777 O3M_20425 Escherichia coli O104:H4 str. 2009EL-2050 hydroxyacylglutathione hydrolase YP_006771706.1 4192618 D 1134782 CDS YP_006771707.1 410484161 13690778 4193445..4194803 1 NC_018650.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); membrane-bound lytic murein transglycosylase D 4194803 mltD 13690778 mltD Escherichia coli O104:H4 str. 2009EL-2050 membrane-bound lytic murein transglycosylase D YP_006771707.1 4193445 D 1134782 CDS YP_006771708.1 410484162 13690779 complement(4194851..4195621) 1 NC_018650.1 COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine-dependent methyltransferase 4195621 13690779 O3M_20435 Escherichia coli O104:H4 str. 2009EL-2050 S-adenosyl-L-methionine-dependent methyltransferase YP_006771708.1 4194851 R 1134782 CDS YP_006771709.1 410484163 13690780 complement(4195699..4196499) 1 NC_018650.1 COG3021 Uncharacterized protein conserved in bacteria; hypothetical protein 4196499 13690780 O3M_20440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771709.1 4195699 R 1134782 CDS YP_006771710.1 410484164 13690781 4196740..4197654 1 NC_018650.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 4197654 13690781 O3M_20445 Escherichia coli O104:H4 str. 2009EL-2050 LysR family transcriptional regulator YP_006771710.1 4196740 D 1134782 CDS YP_006771711.1 410484165 13690782 complement(4197651..4198454) 1 NC_018650.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-diketo-D-gluconate reductase B 4198454 dkgB 13690782 dkgB Escherichia coli O104:H4 str. 2009EL-2050 2,5-diketo-D-gluconate reductase B YP_006771711.1 4197651 R 1134782 CDS YP_006771712.1 410484166 13691518 complement(4204353..4204925) 1 NC_018650.1 COG0241 Histidinol phosphatase and related phosphatases; D,D-heptose 1,7-bisphosphate phosphatase 4204925 13691518 O3M_20455 Escherichia coli O104:H4 str. 2009EL-2050 D,D-heptose 1,7-bisphosphate phosphatase YP_006771712.1 4204353 R 1134782 CDS YP_006771713.1 410484167 13691519 4205113..4206144 1 NC_018650.1 COG1135 ABC-type metal ion transport system, ATPase component; DL-methionine transporter ATP-binding subunit 4206144 metN 13691519 metN Escherichia coli O104:H4 str. 2009EL-2050 DL-methionine transporter ATP-binding subunit YP_006771713.1 4205113 D 1134782 CDS YP_006771714.1 410484168 13691520 4206137..4206790 1 NC_018650.1 COG2011 ABC-type metal ion transport system, permease component; DL-methionine transporter permease 4206790 13691520 O3M_20465 Escherichia coli O104:H4 str. 2009EL-2050 DL-methionine transporter permease YP_006771714.1 4206137 D 1134782 CDS YP_006771715.1 410484169 13691521 4206830..4207645 1 NC_018650.1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; DL-methionine transporter substrate-binding subunit 4207645 metQ 13691521 metQ Escherichia coli O104:H4 str. 2009EL-2050 DL-methionine transporter substrate-binding subunit YP_006771715.1 4206830 D 1134782 CDS YP_006771716.1 410484170 13691522 4207763..4208167 1 NC_018650.1 outer membrane lipoprotein 4208167 rcsF 13691522 rcsF Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein YP_006771716.1 4207763 D 1134782 CDS YP_006771717.1 410484171 13691523 4208164..4208871 1 NC_018650.1 COG1720 Uncharacterized conserved protein; hypothetical protein 4208871 13691523 O3M_20480 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771717.1 4208164 D 1134782 CDS YP_006771718.1 410484172 13691524 4208983..4210701 1 NC_018650.1 COG0442 Prolyl-tRNA synthetase; prolyl-tRNA synthetase 4210701 13691524 O3M_20485 Escherichia coli O104:H4 str. 2009EL-2050 prolyl-tRNA synthetase YP_006771718.1 4208983 D 1134782 CDS YP_006771719.1 410484173 13691525 4210754..4211335 1 NC_018650.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 4211335 13691525 O3M_20490 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771719.1 4210754 D 1134782 CDS YP_006771720.1 410484174 13691526 4211341..4211577 1 NC_018650.1 hypothetical protein 4211577 13691526 O3M_20495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771720.1 4211341 D 1134782 CDS YP_006771721.1 410484175 13691527 complement(4211781..4212761) 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 4212761 13691527 O3M_20500 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006771721.1 4211781 R 1134782 CDS YP_006771722.1 410484176 13691528 complement(4213011..4213721) 1 NC_018650.1 COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance; copper homeostasis and adhesion lipoprotein 4213721 13691528 O3M_20505 Escherichia coli O104:H4 str. 2009EL-2050 copper homeostasis and adhesion lipoprotein YP_006771722.1 4213011 R 1134782 CDS YP_006771723.1 410484177 13691529 complement(4213735..4214157) 1 NC_018650.1 COG1186 Protein chain release factor B; hypothetical protein 4214157 13691529 O3M_20510 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771723.1 4213735 R 1134782 CDS YP_006771724.1 410484178 13691530 complement(4214154..4214699) 1 NC_018650.1 COG4681 Uncharacterized protein conserved in bacteria; hypothetical protein 4214699 13691530 O3M_20515 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771724.1 4214154 R 1134782 CDS YP_006771725.1 410484179 13691531 4214865..4215065 1 NC_018650.1 hypothetical protein 4215065 13691531 O3M_20520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771725.1 4214865 D 1134782 CDS YP_006771726.1 410484180 13691532 4215052..4215312 1 NC_018650.1 COG4568 Transcriptional antiterminator; Rho-binding antiterminator 4215312 13691532 O3M_20525 Escherichia coli O104:H4 str. 2009EL-2050 Rho-binding antiterminator YP_006771726.1 4215052 D 1134782 CDS YP_006771727.1 410484181 13691533 complement(4215361..4216659) 1 NC_018650.1 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile)-lysidine synthetase 4216659 tilS 13691533 tilS Escherichia coli O104:H4 str. 2009EL-2050 tRNA(Ile)-lysidine synthetase YP_006771727.1 4215361 R 1134782 CDS YP_006771728.1 410484182 13691534 complement(4216724..4217113) 1 NC_018650.1 COG0346 Lactoylglutathione lyase and related lyases; lyase 4217113 13691534 O3M_20535 Escherichia coli O104:H4 str. 2009EL-2050 lyase YP_006771728.1 4216724 R 1134782 CDS YP_006771729.1 410484183 13691535 complement(4217170..4219311) 1 NC_018650.1 COG1982 Arginine/lysine/ornithine decarboxylases; lysine decarboxylase LdcC 4219311 13691535 O3M_20540 Escherichia coli O104:H4 str. 2009EL-2050 lysine decarboxylase LdcC YP_006771729.1 4217170 R 1134782 CDS YP_006771730.1 410484184 13691536 complement(4219410..4220369) 1 NC_018650.1 COG0825 Acetyl-CoA carboxylase alpha subunit; acetyl-CoA carboxylase carboxyltransferase subunit alpha 4220369 13691536 O3M_20545 Escherichia coli O104:H4 str. 2009EL-2050 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_006771730.1 4219410 R 1134782 CDS YP_006771731.1 410484185 13691537 complement(4220382..4223864) 1 NC_018650.1 COG0587 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha 4223864 dnaE 13691537 dnaE Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit alpha YP_006771731.1 4220382 R 1134782 CDS YP_006771732.1 410484186 13691538 complement(4223901..4224497) 1 NC_018650.1 COG0164 Ribonuclease HII; ribonuclease HII 4224497 rnhB 13691538 rnhB Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease HII YP_006771732.1 4223901 R 1134782 CDS YP_006771733.1 410484187 13691539 complement(4224494..4225642) 1 NC_018650.1 COG0763 Lipid A disaccharide synthetase; lipid-A-disaccharide synthase 4225642 lpxB 13691539 lpxB Escherichia coli O104:H4 str. 2009EL-2050 lipid-A-disaccharide synthase YP_006771733.1 4224494 R 1134782 CDS YP_006771734.1 410484188 13691540 complement(4225642..4226430) 1 NC_018650.1 COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; UDP-N-acetylglucosamine acyltransferase 4226430 13691540 O3M_20565 Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylglucosamine acyltransferase YP_006771734.1 4225642 R 1134782 CDS YP_006771735.1 410484189 13691541 complement(4226434..4226889) 1 NC_018650.1 COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; (3R)-hydroxymyristoyl-ACP dehydratase 4226889 fabZ 13691541 fabZ Escherichia coli O104:H4 str. 2009EL-2050 (3R)-hydroxymyristoyl-ACP dehydratase YP_006771735.1 4226434 R 1134782 CDS YP_006771736.1 410484190 13691542 complement(4226994..4228019) 1 NC_018650.1 COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 4228019 lpxD 13691542 lpxD Escherichia coli O104:H4 str. 2009EL-2050 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_006771736.1 4226994 R 1134782 CDS YP_006771737.1 410484191 13691543 complement(4228023..4228508) 1 NC_018650.1 COG2825 Outer membrane protein; periplasmic chaperone 4228508 13691543 O3M_20580 Escherichia coli O104:H4 str. 2009EL-2050 periplasmic chaperone YP_006771737.1 4228023 R 1134782 CDS YP_006771738.1 410484192 13691544 complement(4228630..4231062) 1 NC_018650.1 COG4775 Outer membrane protein/protective antigen OMA87; outer membrane protein assembly factor YaeT 4231062 13691544 O3M_20585 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein assembly factor YaeT YP_006771738.1 4228630 R 1134782 CDS YP_006771739.1 410484193 13691545 complement(4231092..4232444) 1 NC_018650.1 COG0750 Predicted membrane-associated Zn-dependent proteases 1; zinc metallopeptidase RseP 4232444 13691545 O3M_20590 Escherichia coli O104:H4 str. 2009EL-2050 zinc metallopeptidase RseP YP_006771739.1 4231092 R 1134782 CDS YP_006771740.1 410484194 13691546 complement(4232456..4233313) 1 NC_018650.1 COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthase 4233313 cdsA 13691546 cdsA Escherichia coli O104:H4 str. 2009EL-2050 CDP-diglyceride synthase YP_006771740.1 4232456 R 1134782 CDS YP_006771741.1 410484195 13691547 complement(4233326..4234084) 1 NC_018650.1 COG0020 Undecaprenyl pyrophosphate synthase; undecaprenyl pyrophosphate synthase 4234084 13691547 O3M_20600 Escherichia coli O104:H4 str. 2009EL-2050 undecaprenyl pyrophosphate synthase YP_006771741.1 4233326 R 1134782 CDS YP_006771742.1 410484196 13691548 complement(4234273..4235469) 1 NC_018650.1 COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4235469 13691548 O3M_20605 Escherichia coli O104:H4 str. 2009EL-2050 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_006771742.1 4234273 R 1134782 CDS YP_006771743.1 410484197 13691549 complement(4235561..4236118) 1 NC_018650.1 COG0233 Ribosome recycling factor; ribosome recycling factor 4236118 frr 13691549 frr Escherichia coli O104:H4 str. 2009EL-2050 ribosome recycling factor YP_006771743.1 4235561 R 1134782 CDS YP_006771744.1 410484198 13691550 complement(4236410..4237135) 1 NC_018650.1 COG0528 Uridylate kinase; uridylate kinase 4237135 pyrH 13691550 pyrH Escherichia coli O104:H4 str. 2009EL-2050 uridylate kinase YP_006771744.1 4236410 R 1134782 CDS YP_006771745.1 410484199 13691551 complement(4237282..4238133) 1 NC_018650.1 COG0264 Translation elongation factor Ts; elongation factor Ts 4238133 tsf 13691551 tsf Escherichia coli O104:H4 str. 2009EL-2050 elongation factor Ts YP_006771745.1 4237282 R 1134782 CDS YP_006771746.1 410484200 13691552 complement(4238391..4239116) 1 NC_018650.1 COG0052 Ribosomal protein S2; 30S ribosomal protein S2 4239116 rpsB 13691552 rpsB Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S2 YP_006771746.1 4238391 R 1134782 CDS YP_006771747.1 410484201 13691553 4239484..4240278 1 NC_018650.1 COG0024 Methionine aminopeptidase; methionine aminopeptidase 4240278 13691553 O3M_20630 Escherichia coli O104:H4 str. 2009EL-2050 methionine aminopeptidase YP_006771747.1 4239484 D 1134782 CDS YP_006771748.1 410484202 13691554 4240340..4243012 1 NC_018650.1 COG2844 UTP:GlnB (protein PII) uridylyltransferase; PII uridylyl-transferase 4243012 13691554 O3M_20635 Escherichia coli O104:H4 str. 2009EL-2050 PII uridylyl-transferase YP_006771748.1 4240340 D 1134782 CDS YP_006771749.1 410484203 13691555 4243043..4243867 1 NC_018650.1 COG2171 Tetrahydrodipicolinate N-succinyltransferase; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 4243867 dapD 13691555 dapD Escherichia coli O104:H4 str. 2009EL-2050 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_006771749.1 4243043 D 1134782 CDS YP_006771750.1 410484204 13691556 4244182..4244568 1 NC_018650.1 hypothetical protein 4244568 13691556 O3M_20645 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771750.1 4244182 D 1134782 CDS YP_006771751.1 410484205 13691557 complement(4244657..4245814) 1 NC_018650.1 COG3835 Sugar diacid utilization regulator; carbohydrate diacid transcriptional activator CdaR 4245814 13691557 O3M_20650 Escherichia coli O104:H4 str. 2009EL-2050 carbohydrate diacid transcriptional activator CdaR YP_006771751.1 4244657 R 1134782 CDS YP_006771752.1 410484206 13691558 complement(4245969..4247393) 1 NC_018650.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease 4247393 13691558 O3M_20655 Escherichia coli O104:H4 str. 2009EL-2050 serine endoprotease YP_006771752.1 4245969 R 1134782 CDS YP_006771753.1 410484207 13691559 complement(4247523..4249040) 1 NC_018650.1 COG0232 dGTP triphosphohydrolase; deoxyguanosinetriphosphate triphosphohydrolase 4249040 dgt 13691559 dgt Escherichia coli O104:H4 str. 2009EL-2050 deoxyguanosinetriphosphate triphosphohydrolase YP_006771753.1 4247523 R 1134782 CDS YP_006771754.1 410484208 13691560 4249124..4249822 1 NC_018650.1 COG0775 Nucleoside phosphorylase; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 4249822 13691560 O3M_20665 Escherichia coli O104:H4 str. 2009EL-2050 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_006771754.1 4249124 D 1134782 CDS YP_006771755.1 410484209 13691561 4249815..4250615 1 NC_018650.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; vitamin B12-transporter protein BtuF 4250615 13691561 O3M_20670 Escherichia coli O104:H4 str. 2009EL-2050 vitamin B12-transporter protein BtuF YP_006771755.1 4249815 D 1134782 CDS YP_006771756.1 410484210 13691562 4250653..4251276 1 NC_018650.1 COG2860 Predicted membrane protein; hypothetical protein 4251276 13691562 O3M_20675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771756.1 4250653 D 1134782 CDS YP_006771757.1 410484211 13691563 complement(4251323..4251667) 1 NC_018650.1 COG0316 Uncharacterized conserved protein; iron-sulfur cluster insertion protein ErpA 4251667 13691563 O3M_20680 Escherichia coli O104:H4 str. 2009EL-2050 iron-sulfur cluster insertion protein ErpA YP_006771757.1 4251323 R 1134782 CDS YP_006771758.1 410484212 13691564 complement(4251749..4253170) 1 NC_018650.1 COG0038 Chloride channel protein EriC; chloride channel protein 4253170 13691564 O3M_20685 Escherichia coli O104:H4 str. 2009EL-2050 chloride channel protein YP_006771758.1 4251749 R 1134782 CDS YP_006771759.1 410484213 13691565 4253395..4254675 1 NC_018650.1 COG0001 Glutamate-1-semialdehyde aminotransferase; glutamate-1-semialdehyde aminotransferase 4254675 13691565 O3M_20690 Escherichia coli O104:H4 str. 2009EL-2050 glutamate-1-semialdehyde aminotransferase YP_006771759.1 4253395 D 1134782 CDS YP_006771760.1 410484214 13691566 complement(4254710..4256692) 1 NC_018650.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-hydroxamate transporter permease subunit 4256692 13691566 O3M_20695 Escherichia coli O104:H4 str. 2009EL-2050 iron-hydroxamate transporter permease subunit YP_006771760.1 4254710 R 1134782 CDS YP_006771761.1 410484215 13691567 complement(4256689..4257579) 1 NC_018650.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; iron-hydroxamate transporter substrate-binding subunit 4257579 13691567 O3M_20700 Escherichia coli O104:H4 str. 2009EL-2050 iron-hydroxamate transporter substrate-binding subunit YP_006771761.1 4256689 R 1134782 CDS YP_006771762.1 410484216 13691568 complement(4257579..4258376) 1 NC_018650.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-hydroxamate transporter ATP-binding subunit 4258376 13691568 O3M_20705 Escherichia coli O104:H4 str. 2009EL-2050 iron-hydroxamate transporter ATP-binding subunit YP_006771762.1 4257579 R 1134782 CDS YP_006771763.1 410484217 13691569 complement(4258427..4260670) 1 NC_018650.1 COG1629 Outer membrane receptor proteins, mostly Fe transport; ferrichrome outer membrane transporter 4260670 13691569 O3M_20710 Escherichia coli O104:H4 str. 2009EL-2050 ferrichrome outer membrane transporter YP_006771763.1 4258427 R 1134782 CDS YP_006771764.1 410484218 13691570 complement(4260890..4263424) 1 NC_018650.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); bifunctional glycosyl transferase/transpeptidase 4263424 mrcB 13691570 mrcB Escherichia coli O104:H4 str. 2009EL-2050 bifunctional glycosyl transferase/transpeptidase YP_006771764.1 4260890 R 1134782 CDS YP_006771765.1 410484219 13691571 complement(4263411..4263617) 1 NC_018650.1 hypothetical protein 4263617 13691571 O3M_20720 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771765.1 4263411 R 1134782 CDS YP_006771766.1 410484220 13691572 complement(4263620..4266049) 1 NC_018650.1 COG1643 HrpA-like helicases; ATP-dependent RNA helicase HrpB 4266049 13691572 O3M_20725 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent RNA helicase HrpB YP_006771766.1 4263620 R 1134782 CDS YP_006771767.1 410484221 13691573 4266123..4266653 1 NC_018650.1 COG1514 2'-5' RNA ligase; 2'-5' RNA ligase 4266653 13691573 O3M_20730 Escherichia coli O104:H4 str. 2009EL-2050 2'-5' RNA ligase YP_006771767.1 4266123 D 1134782 CDS YP_006771768.1 410484222 13691574 4266668..4267372 1 NC_018650.1 COG1489 DNA-binding protein, stimulates sugar fermentation; DNA-binding transcriptional regulator 4267372 13691574 O3M_20735 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771768.1 4266668 D 1134782 CDS YP_006771769.1 410484223 13691575 4267550..4268005 1 NC_018650.1 COG1734 DnaK suppressor protein; RNA polymerase-binding transcription factor 4268005 dksA 13691575 dksA Escherichia coli O104:H4 str. 2009EL-2050 RNA polymerase-binding transcription factor YP_006771769.1 4267550 D 1134782 CDS YP_006771770.1 410484224 13691576 4268042..4268968 1 NC_018650.1 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-Q tRNA(Asp) synthetase 4268968 13691576 O3M_20745 Escherichia coli O104:H4 str. 2009EL-2050 glutamyl-Q tRNA(Asp) synthetase YP_006771770.1 4268042 D 1134782 CDS YP_006771771.1 410484225 13691577 4269007..4270425 1 NC_018650.1 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; poly(A) polymerase I 4270425 pcnB 13691577 pcnB Escherichia coli O104:H4 str. 2009EL-2050 poly(A) polymerase I YP_006771771.1 4269007 D 1134782 CDS YP_006771772.1 410484226 13691578 4270422..4270901 1 NC_018650.1 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 4270901 13691578 O3M_20755 Escherichia coli O104:H4 str. 2009EL-2050 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_006771772.1 4270422 D 1134782 CDS YP_006771773.1 410484227 13691579 4271271..4271855 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial-like protein 4271855 13691579 O3M_20760 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like protein YP_006771773.1 4271271 D 1134782 CDS YP_006771774.1 410484228 13691580 4271960..4272700 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; chaperone protein EcpD 4272700 13691580 O3M_20765 Escherichia coli O104:H4 str. 2009EL-2050 chaperone protein EcpD YP_006771774.1 4271960 D 1134782 CDS YP_006771775.1 410484229 13691581 4272735..4275335 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; fimbrial outer membrane usher protein 4275335 13691581 O3M_20770 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial outer membrane usher protein YP_006771775.1 4272735 D 1134782 CDS YP_006771776.1 410484230 13691582 4275352..4275921 1 NC_018650.1 fimbrial protein 4275921 13691582 O3M_20775 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein YP_006771776.1 4275352 D 1134782 CDS YP_006771777.1 410484231 13691583 4275936..4276538 1 NC_018650.1 fimbrial protein StaE 4276538 13691583 O3M_20780 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein StaE YP_006771777.1 4275936 D 1134782 CDS YP_006771778.1 410484232 13691584 4276565..4277161 1 NC_018650.1 fimbrial protein StaF 4277161 13691584 O3M_20785 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein StaF YP_006771778.1 4276565 D 1134782 CDS YP_006771779.1 410484233 13691585 4277214..4278488 1 NC_018650.1 fimbrial-like adhesin protein 4278488 13691585 O3M_20790 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial-like adhesin protein YP_006771779.1 4277214 D 1134782 CDS YP_006771780.1 410484234 13691586 4278601..4279395 1 NC_018650.1 COG0413 Ketopantoate hydroxymethyltransferase; 3-methyl-2-oxobutanoate hydroxymethyltransferase 4279395 panB 13691586 panB Escherichia coli O104:H4 str. 2009EL-2050 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_006771780.1 4278601 D 1134782 CDS YP_006771781.1 410484235 13691587 4279407..4280258 1 NC_018650.1 COG0414 Panthothenate synthetase; pantoate--beta-alanine ligase 4280258 panC 13691587 panC Escherichia coli O104:H4 str. 2009EL-2050 pantoate--beta-alanine ligase YP_006771781.1 4279407 D 1134782 CDS YP_006771782.1 410484236 13691588 complement(4280332..4281234) 1 NC_018650.1 transposase 4281234 13691588 O3M_20805 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771782.1 4280332 R 1134782 CDS YP_006771783.1 410484237 13691589 4281508..4281888 1 NC_018650.1 COG0853 Aspartate 1-decarboxylase; aspartate alpha-decarboxylase 4281888 13691589 O3M_20810 Escherichia coli O104:H4 str. 2009EL-2050 aspartate alpha-decarboxylase YP_006771783.1 4281508 D 1134782 CDS YP_006771784.1 410484238 13691590 complement(4281892..4283121) 1 NC_018650.1 COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase 4283121 13691590 O3M_20815 Escherichia coli O104:H4 str. 2009EL-2050 polysaccharide deacetylase YP_006771784.1 4281892 R 1134782 CDS YP_006771785.1 410484239 13691591 complement(4283185..4283625) 1 NC_018650.1 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system transporter subunit IIA 4283625 13691591 O3M_20820 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter subunit IIA YP_006771785.1 4283185 R 1134782 CDS YP_006771786.1 410484240 13691592 complement(4283730..4284500) 1 NC_018650.1 COG0842 ABC-type multidrug transport system, permease component; inner membrane transport permease 4284500 13691592 O3M_20825 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane transport permease YP_006771786.1 4283730 R 1134782 CDS YP_006771787.1 410484241 13691593 complement(4284497..4285423) 1 NC_018650.1 COG1131 ABC-type multidrug transport system, ATPase component; transporter subunit 4285423 13691593 O3M_20830 Escherichia coli O104:H4 str. 2009EL-2050 transporter subunit YP_006771787.1 4284497 R 1134782 CDS YP_006771788.1 410484242 13691594 4285532..4286194 1 NC_018650.1 COG0288 Carbonic anhydrase; carbonic anhydrase 4286194 13691594 O3M_20835 Escherichia coli O104:H4 str. 2009EL-2050 carbonic anhydrase YP_006771788.1 4285532 D 1134782 CDS YP_006771789.1 410484243 13691676 complement(4286235..4286771) 1 NC_018650.1 COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 4286771 13691676 O3M_20840 Escherichia coli O104:H4 str. 2009EL-2050 hypoxanthine phosphoribosyltransferase YP_006771789.1 4286235 R 1134782 CDS YP_006771790.1 410484244 13691677 4286977..4289367 1 NC_018650.1 COG4993 Glucose dehydrogenase; glucose dehydrogenase 4289367 13691677 O3M_20845 Escherichia coli O104:H4 str. 2009EL-2050 glucose dehydrogenase YP_006771790.1 4286977 D 1134782 CDS YP_006771791.1 410484245 13691678 complement(4289414..4290964) 1 NC_018650.1 COG2132 Putative multicopper oxidases; multicopper oxidase 4290964 13691678 O3M_20850 Escherichia coli O104:H4 str. 2009EL-2050 multicopper oxidase YP_006771791.1 4289414 R 1134782 CDS YP_006771792.1 410484246 13691679 4291130..4291477 1 NC_018650.1 hypothetical protein 4291477 13691679 O3M_20855 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771792.1 4291130 D 1134782 CDS YP_006771793.1 410484247 13691680 4291583..4292449 1 NC_018650.1 COG0421 Spermidine synthase; spermidine synthase 4292449 13691680 O3M_20860 Escherichia coli O104:H4 str. 2009EL-2050 spermidine synthase YP_006771793.1 4291583 D 1134782 CDS YP_006771794.1 410484248 13691681 4292465..4293259 1 NC_018650.1 COG1586 S-adenosylmethionine decarboxylase; S-adenosylmethionine decarboxylase 4293259 13691681 O3M_20865 Escherichia coli O104:H4 str. 2009EL-2050 S-adenosylmethionine decarboxylase YP_006771794.1 4292465 D 1134782 CDS YP_006771795.1 410484249 13691682 complement(4293297..4293659) 1 NC_018650.1 COG3112 Uncharacterized protein conserved in bacteria; hypothetical protein 4293659 13691682 O3M_20870 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771795.1 4293297 R 1134782 CDS YP_006771796.1 410484250 13691683 complement(4293835..4296432) 1 NC_018650.1 COG1049 Aconitase B; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 4296432 13691683 O3M_20875 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_006771796.1 4293835 R 1134782 CDS YP_006771797.1 410484251 13691684 4296787..4298544 1 NC_018650.1 hypothetical protein 4298544 13691684 O3M_20880 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771797.1 4296787 D 1134782 CDS YP_006771798.1 410484252 13691685 complement(4298615..4300039) 1 NC_018650.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; dihydrolipoamide dehydrogenase 4300039 13691685 O3M_20885 Escherichia coli O104:H4 str. 2009EL-2050 dihydrolipoamide dehydrogenase YP_006771798.1 4298615 R 1134782 CDS YP_006771799.1 410484253 13691686 complement(4300364..4302256) 1 NC_018650.1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; pyruvate dehydrogenase dihydrolipoyltransacetylase 4302256 aceF 13691686 aceF Escherichia coli O104:H4 str. 2009EL-2050 pyruvate dehydrogenase dihydrolipoyltransacetylase YP_006771799.1 4300364 R 1134782 CDS YP_006771800.1 410484254 13691687 complement(4302271..4304934) 1 NC_018650.1 COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component; pyruvate dehydrogenase subunit E1 4304934 aceE 13691687 aceE Escherichia coli O104:H4 str. 2009EL-2050 pyruvate dehydrogenase subunit E1 YP_006771800.1 4302271 R 1134782 CDS YP_006771801.1 410484255 13691688 complement(4305095..4305859) 1 NC_018650.1 COG2186 Transcriptional regulators; transcriptional regulator PdhR 4305859 pdhR 13691688 pdhR Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator PdhR YP_006771801.1 4305095 R 1134782 CDS YP_006771802.1 410484256 13691689 4306403..4307773 1 NC_018650.1 COG1113 Gamma-aminobutyrate permease and related permeases; aromatic amino acid transporter 4307773 13691689 O3M_20905 Escherichia coli O104:H4 str. 2009EL-2050 aromatic amino acid transporter YP_006771802.1 4306403 D 1134782 CDS YP_006771803.1 410484257 13691690 complement(4307816..4308670) 1 NC_018650.1 COG1270 Cobalamin biosynthesis protein CobD/CbiB; regulatory protein AmpE 4308670 13691690 O3M_20910 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein AmpE YP_006771803.1 4307816 R 1134782 CDS YP_006771804.1 410484258 13691691 complement(4308667..4309218) 1 NC_018650.1 COG3023 Negative regulator of beta-lactamase expression; N-acetyl-anhydromuranmyl-L-alanine amidase 4309218 13691691 O3M_20915 Escherichia coli O104:H4 str. 2009EL-2050 N-acetyl-anhydromuranmyl-L-alanine amidase YP_006771804.1 4308667 R 1134782 CDS YP_006771805.1 410484259 13691692 4309306..4310199 1 NC_018650.1 COG0157 Nicotinate-nucleotide pyrophosphorylase; quinolinate phosphoribosyltransferase 4310199 13691692 O3M_20920 Escherichia coli O104:H4 str. 2009EL-2050 quinolinate phosphoribosyltransferase YP_006771805.1 4309306 D 1134782 CDS YP_006771806.1 410484260 13691693 4310402..4310842 1 NC_018650.1 COG4969 Tfp pilus assembly protein, major pilin PilA; major pilin subunit 4310842 13691693 O3M_20925 Escherichia coli O104:H4 str. 2009EL-2050 major pilin subunit YP_006771806.1 4310402 D 1134782 CDS YP_006771807.1 410484261 13691694 4310852..4312237 1 NC_018650.1 COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; hypothetical protein 4312237 13691694 O3M_20930 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771807.1 4310852 D 1134782 CDS YP_006771808.1 410484262 13691695 4312227..4313429 1 NC_018650.1 COG1459 Type II secretory pathway, component PulF; type IV pilin biogenesis protein 4313429 13691695 O3M_20935 Escherichia coli O104:H4 str. 2009EL-2050 type IV pilin biogenesis protein YP_006771808.1 4312227 D 1134782 CDS YP_006771809.1 410484263 13691696 complement(4313464..4314507) 1 NC_018650.1 COG0516 IMP dehydrogenase/GMP reductase; guanosine 5'-monophosphate oxidoreductase 4314507 13691696 O3M_20940 Escherichia coli O104:H4 str. 2009EL-2050 guanosine 5'-monophosphate oxidoreductase YP_006771809.1 4313464 R 1134782 CDS YP_006771810.1 410484264 13691697 4314732..4315352 1 NC_018650.1 COG0237 Dephospho-CoA kinase; dephospho-CoA kinase 4315352 coaE 13691697 coaE Escherichia coli O104:H4 str. 2009EL-2050 dephospho-CoA kinase YP_006771810.1 4314732 D 1134782 CDS YP_006771811.1 410484265 13691698 4315352..4316095 1 NC_018650.1 COG4582 Uncharacterized protein conserved in bacteria; hypothetical protein 4316095 13691698 O3M_20950 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771811.1 4315352 D 1134782 CDS YP_006771812.1 410484266 13691699 4316105..4316302 1 NC_018650.1 COG3024 Uncharacterized protein conserved in bacteria; DNA gyrase inhibitor 4316302 13691699 O3M_20955 Escherichia coli O104:H4 str. 2009EL-2050 DNA gyrase inhibitor YP_006771812.1 4316105 D 1134782 CDS YP_006771813.1 410484267 13691700 complement(4316402..4316791) 1 NC_018650.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; nucleoside triphosphate pyrophosphohydrolase 4316791 13691700 O3M_20960 Escherichia coli O104:H4 str. 2009EL-2050 nucleoside triphosphate pyrophosphohydrolase YP_006771813.1 4316402 R 1134782 CDS YP_006771814.1 410484268 13691701 complement(4316851..4319556) 1 NC_018650.1 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); preprotein translocase subunit SecA 4319556 13691701 O3M_20965 Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit SecA YP_006771814.1 4316851 R 1134782 CDS YP_006771815.1 410484269 13691702 complement(4319618..4320130) 1 NC_018650.1 SecA regulator SecM 4320130 13691702 O3M_20970 Escherichia coli O104:H4 str. 2009EL-2050 SecA regulator SecM YP_006771815.1 4319618 R 1134782 CDS YP_006771816.1 410484270 13691703 complement(4320361..4321278) 1 NC_018650.1 COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 4321278 lpxC 13691703 lpxC Escherichia coli O104:H4 str. 2009EL-2050 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_006771816.1 4320361 R 1134782 CDS YP_006771817.1 410484271 13691704 complement(4321379..4322530) 1 NC_018650.1 COG0206 Cell division GTPase; cell division protein FtsZ 4322530 13691704 O3M_20980 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsZ YP_006771817.1 4321379 R 1134782 CDS YP_006771818.1 410484272 13691705 complement(4322591..4323853) 1 NC_018650.1 COG0849 Actin-like ATPase involved in cell division; cell division protein FtsA 4323853 ftsA 13691705 ftsA Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsA YP_006771818.1 4322591 R 1134782 CDS YP_006771819.1 410484273 13691706 complement(4323850..4324680) 1 NC_018650.1 COG1589 Cell division septal protein; cell division protein FtsQ 4324680 13691706 O3M_20990 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsQ YP_006771819.1 4323850 R 1134782 CDS YP_006771820.1 410484274 13691707 complement(4324682..4325602) 1 NC_018650.1 D-alanine-D-alanine ligase A; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanyl-alanine synthetase A 4325602 ddl 13691707 ddl Escherichia coli O104:H4 str. 2009EL-2050 D-alanyl-alanine synthetase A YP_006771820.1 4324682 R 1134782 CDS YP_006771821.1 410484275 13691708 complement(4325595..4327070) 1 NC_018650.1 COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate--L-alanine ligase 4327070 murC 13691708 murC Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylmuramate--L-alanine ligase YP_006771821.1 4325595 R 1134782 CDS YP_006771822.1 410484276 13691709 complement(4327124..4328191) 1 NC_018650.1 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4328191 murG 13691709 murG Escherichia coli O104:H4 str. 2009EL-2050 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_006771822.1 4327124 R 1134782 CDS YP_006771823.1 410484277 13691710 complement(4328188..4329432) 1 NC_018650.1 COG0772 Bacterial cell division membrane protein; cell division protein FtsW 4329432 13691710 O3M_21010 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsW YP_006771823.1 4328188 R 1134782 CDS YP_006771824.1 410484278 13691711 complement(4329432..4330748) 1 NC_018650.1 COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 4330748 murD 13691711 murD Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_006771824.1 4329432 R 1134782 CDS YP_006771825.1 410484279 13691712 complement(4330751..4331833) 1 NC_018650.1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase 4331833 mraY 13691712 mraY Escherichia coli O104:H4 str. 2009EL-2050 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_006771825.1 4330751 R 1134782 CDS YP_006771826.1 410484280 13691713 complement(4331827..4333185) 1 NC_018650.1 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 4333185 murF 13691713 murF Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_006771826.1 4331827 R 1134782 CDS YP_006771827.1 410484281 13691714 complement(4333182..4334669) 1 NC_018650.1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 4334669 murE 13691714 murE Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_006771827.1 4333182 R 1134782 CDS YP_006771828.1 410484282 13691715 complement(4334656..4336422) 1 NC_018650.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; peptidoglycan synthase FtsI 4336422 13691715 O3M_21035 Escherichia coli O104:H4 str. 2009EL-2050 peptidoglycan synthase FtsI YP_006771828.1 4334656 R 1134782 CDS YP_006771829.1 410484283 13691716 complement(4336438..4336803) 1 NC_018650.1 COG3116 Cell division protein; cell division protein FtsL 4336803 13691716 O3M_21040 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsL YP_006771829.1 4336438 R 1134782 CDS YP_006771830.1 410484284 13691717 complement(4336800..4337741) 1 NC_018650.1 COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; 16S rRNA m(4)C1402 methyltransferase 4337741 13691717 O3M_21045 Escherichia coli O104:H4 str. 2009EL-2050 16S rRNA m(4)C1402 methyltransferase YP_006771830.1 4336800 R 1134782 CDS YP_006771831.1 410484285 13691718 complement(4337743..4338201) 1 NC_018650.1 COG2001 Uncharacterized protein conserved in bacteria; cell division protein MraZ 4338201 13691718 O3M_21050 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein MraZ YP_006771831.1 4337743 R 1134782 CDS YP_006771832.1 410484286 13691719 complement(4338803..4339807) 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional regulator FruR 4339807 13691719 O3M_21055 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator FruR YP_006771832.1 4338803 R 1134782 CDS YP_006771833.1 410484287 13691720 complement(4339987..4340478) 1 NC_018650.1 COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase 3 regulatory subunit 4340478 ilvH 13691720 ilvH Escherichia coli O104:H4 str. 2009EL-2050 acetolactate synthase 3 regulatory subunit YP_006771833.1 4339987 R 1134782 CDS YP_006771834.1 410484288 13691721 complement(4340481..4342205) 1 NC_018650.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase 3 catalytic subunit 4342205 13691721 O3M_21065 Escherichia coli O104:H4 str. 2009EL-2050 acetolactate synthase 3 catalytic subunit YP_006771834.1 4340481 R 1134782 CDS YP_006771835.1 410484289 13691722 complement(4342523..4343467) 1 NC_018650.1 COG0583 Transcriptional regulator; leucine transcriptional activator 4343467 leuO 13691722 leuO Escherichia coli O104:H4 str. 2009EL-2050 leucine transcriptional activator YP_006771835.1 4342523 R 1134782 CDS YP_006771836.1 410484290 13691723 4344128..4344214 1 NC_018650.1 leu operon leader peptide 4344214 13691723 O3M_21075 Escherichia coli O104:H4 str. 2009EL-2050 leu operon leader peptide YP_006771836.1 4344128 D 1134782 CDS YP_006771837.1 410484291 13691724 4344307..4345878 1 NC_018650.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; 2-isopropylmalate synthase 4345878 13691724 O3M_21080 Escherichia coli O104:H4 str. 2009EL-2050 2-isopropylmalate synthase YP_006771837.1 4344307 D 1134782 CDS YP_006771838.1 410484292 13691725 4345878..4346969 1 NC_018650.1 COG0473 Isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 4346969 13691725 O3M_21085 Escherichia coli O104:H4 str. 2009EL-2050 3-isopropylmalate dehydrogenase YP_006771838.1 4345878 D 1134782 CDS YP_006771839.1 410484293 13691726 4346972..4348372 1 NC_018650.1 COG0065 3-isopropylmalate dehydratase large subunit; isopropylmalate isomerase large subunit 4348372 13691726 O3M_21090 Escherichia coli O104:H4 str. 2009EL-2050 isopropylmalate isomerase large subunit YP_006771839.1 4346972 D 1134782 CDS YP_006771840.1 410484294 13691727 4348383..4348988 1 NC_018650.1 COG0066 3-isopropylmalate dehydratase small subunit; isopropylmalate isomerase small subunit 4348988 leuD 13691727 leuD Escherichia coli O104:H4 str. 2009EL-2050 isopropylmalate isomerase small subunit YP_006771840.1 4348383 D 1134782 CDS YP_006771841.1 410484295 13691728 complement(4349037..4350215) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; broad specificity sugar efflux system SetA 4350215 13691728 O3M_21100 Escherichia coli O104:H4 str. 2009EL-2050 broad specificity sugar efflux system SetA YP_006771841.1 4349037 R 1134782 CDS YP_006771842.1 410484296 13691729 complement(4350317..4350448) 1 NC_018650.1 hypothetical protein 4350448 13691729 O3M_21105 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771842.1 4350317 R 1134782 CDS YP_006771843.1 410484297 13691730 4350537..4352192 1 NC_018650.1 COG4533 ABC-type uncharacterized transport system, periplasmic component; transcriptional regulator SgrR 4352192 13691730 O3M_21110 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator SgrR YP_006771843.1 4350537 D 1134782 CDS YP_006771844.1 410484298 13691731 4352356..4353339 1 NC_018650.1 COG4143 ABC-type thiamine transport system, periplasmic component; thiamine transporter substrate binding subunit 4353339 tbpA 13691731 tbpA Escherichia coli O104:H4 str. 2009EL-2050 thiamine transporter substrate binding subunit YP_006771844.1 4352356 D 1134782 CDS YP_006771845.1 410484299 13691732 4353315..4354925 1 NC_018650.1 COG0555 ABC-type sulfate transport system, permease component; thiamine transporter membrane protein 4354925 thiP 13691732 thiP Escherichia coli O104:H4 str. 2009EL-2050 thiamine transporter membrane protein YP_006771845.1 4353315 D 1134782 CDS YP_006771846.1 410484300 13691733 4354909..4355607 1 NC_018650.1 COG3840 ABC-type thiamine transport system, ATPase component; thiamine transporter ATP-binding subunit 4355607 thiQ 13691733 thiQ Escherichia coli O104:H4 str. 2009EL-2050 thiamine transporter ATP-binding subunit YP_006771846.1 4354909 D 1134782 CDS YP_006771847.1 410484301 13691734 complement(4355721..4356485) 1 NC_018650.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 4356485 13691734 O3M_21130 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771847.1 4355721 R 1134782 CDS YP_006771848.1 410484302 13691735 complement(4356571..4357449) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator AraC 4357449 13691735 O3M_21135 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator AraC YP_006771848.1 4356571 R 1134782 CDS YP_006771849.1 410484303 13691736 4357788..4359488 1 NC_018650.1 COG1069 Ribulose kinase; ribulokinase 4359488 13691736 O3M_21140 Escherichia coli O104:H4 str. 2009EL-2050 ribulokinase YP_006771849.1 4357788 D 1134782 CDS YP_006771850.1 410484304 13691737 4359499..4361001 1 NC_018650.1 COG2160 L-arabinose isomerase; L-arabinose isomerase 4361001 13691737 O3M_21145 Escherichia coli O104:H4 str. 2009EL-2050 L-arabinose isomerase YP_006771850.1 4359499 D 1134782 CDS YP_006771851.1 410484305 13691738 4361170..4361865 1 NC_018650.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase 4361865 araD 13691738 araD Escherichia coli O104:H4 str. 2009EL-2050 L-ribulose-5-phosphate 4-epimerase YP_006771851.1 4361170 D 1134782 CDS YP_006771852.1 410484306 13691739 4361940..4364291 1 NC_018650.1 COG0417 DNA polymerase elongation subunit (family B); DNA polymerase II 4364291 13691739 O3M_21155 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase II YP_006771852.1 4361940 D 1134782 CDS YP_006771853.1 410484307 13691740 4364456..4367362 1 NC_018650.1 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; ATP-dependent helicase HepA 4367362 13691740 O3M_21160 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent helicase HepA YP_006771853.1 4364456 D 1134782 CDS YP_006771854.1 410484308 13691741 4367374..4368033 1 NC_018650.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S rRNA/tRNA pseudouridine synthase A 4368033 13691741 O3M_21165 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA/tRNA pseudouridine synthase A YP_006771854.1 4367374 D 1134782 CDS YP_006771855.1 410484309 13691742 complement(4368150..4368965) 1 NC_018650.1 COG1076 DnaJ-domain-containing proteins 1; Dna-J like membrane chaperone protein 4368965 djlA 13691742 djlA Escherichia coli O104:H4 str. 2009EL-2050 Dna-J like membrane chaperone protein YP_006771855.1 4368150 R 1134782 CDS YP_006771856.1 410484310 13691743 4369220..4371574 1 NC_018650.1 COG1452 Organic solvent tolerance protein OstA; LPS assembly outer membrane complex protein LptD 4371574 13691743 O3M_21175 Escherichia coli O104:H4 str. 2009EL-2050 LPS assembly outer membrane complex protein LptD YP_006771856.1 4369220 D 1134782 CDS YP_006771857.1 410484311 13691744 4371627..4372913 1 NC_018650.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; peptidyl-prolyl cis-trans isomerase SurA 4372913 13691744 O3M_21180 Escherichia coli O104:H4 str. 2009EL-2050 peptidyl-prolyl cis-trans isomerase SurA YP_006771857.1 4371627 D 1134782 CDS YP_006771858.1 410484312 13691745 4372913..4373902 1 NC_018650.1 COG1995 Pyridoxal phosphate biosynthesis protein; 4-hydroxythreonine-4-phosphate dehydrogenase 4373902 pdxA 13691745 pdxA Escherichia coli O104:H4 str. 2009EL-2050 4-hydroxythreonine-4-phosphate dehydrogenase YP_006771858.1 4372913 D 1134782 CDS YP_006771859.1 410484313 13691746 4373899..4374720 1 NC_018650.1 COG0030 Dimethyladenosine transferase (rRNA methylation); KsgA/Dim1 family 16S ribosomal RNA methyltransferase 4374720 ksgA 13691746 ksgA Escherichia coli O104:H4 str. 2009EL-2050 KsgA/Dim1 family 16S ribosomal RNA methyltransferase YP_006771859.1 4373899 D 1134782 CDS YP_006771860.1 410484314 13691747 4374723..4375100 1 NC_018650.1 COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport; CO2+/MG2+ efflux protein ApaG 4375100 apaG 13691747 apaG Escherichia coli O104:H4 str. 2009EL-2050 CO2+/MG2+ efflux protein ApaG YP_006771860.1 4374723 D 1134782 CDS YP_006771861.1 410484315 13691748 4375107..4375949 1 NC_018650.1 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase 4375949 apaH 13691748 apaH Escherichia coli O104:H4 str. 2009EL-2050 diadenosine tetraphosphatase YP_006771861.1 4375107 D 1134782 CDS YP_006771862.1 410484316 13691749 complement(4376027..4376506) 1 NC_018650.1 COG0262 Dihydrofolate reductase; dihydrofolate reductase 4376506 folA 13691749 folA Escherichia coli O104:H4 str. 2009EL-2050 dihydrofolate reductase YP_006771862.1 4376027 R 1134782 CDS YP_006771863.1 410484317 13691750 complement(4376698..4378560) 1 NC_018650.1 COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefC 4378560 13691750 O3M_21210 Escherichia coli O104:H4 str. 2009EL-2050 glutathione-regulated potassium-efflux system protein KefC YP_006771863.1 4376698 R 1134782 CDS YP_006771864.1 410484318 13691751 complement(4378553..4379083) 1 NC_018650.1 COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); glutathione-regulated potassium-efflux system ancillary protein KefF 4379083 13691751 O3M_21215 Escherichia coli O104:H4 str. 2009EL-2050 glutathione-regulated potassium-efflux system ancillary protein KefF YP_006771864.1 4378553 R 1134782 CDS YP_006771865.1 410484319 13691752 complement(4379191..4380522) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 4380522 13691752 O3M_21220 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771865.1 4379191 R 1134782 CDS YP_006771866.1 410484320 13691753 complement(4380581..4380868) 1 NC_018650.1 COG2440 Ferredoxin-like protein; ferredoxin-like protein FixX 4380868 13691753 O3M_21225 Escherichia coli O104:H4 str. 2009EL-2050 ferredoxin-like protein FixX YP_006771866.1 4380581 R 1134782 CDS YP_006771867.1 410484321 13691754 complement(4380865..4382151) 1 NC_018650.1 COG0644 Dehydrogenases (flavoproteins); oxidoreductase FixC 4382151 13691754 O3M_21230 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase FixC YP_006771867.1 4380865 R 1134782 CDS YP_006771868.1 410484322 13691755 complement(4382202..4383143) 1 NC_018650.1 COG2025 Electron transfer flavoprotein, alpha subunit; electron transfer flavoprotein FixB 4383143 fixB 13691755 fixB Escherichia coli O104:H4 str. 2009EL-2050 electron transfer flavoprotein FixB YP_006771868.1 4382202 R 1134782 CDS YP_006771869.1 410484323 13691756 complement(4383158..4383928) 1 NC_018650.1 COG2086 Electron transfer flavoprotein, beta subunit; electron transfer flavoprotein FixA 4383928 13691756 O3M_21240 Escherichia coli O104:H4 str. 2009EL-2050 electron transfer flavoprotein FixA YP_006771869.1 4383158 R 1134782 CDS YP_006771870.1 410484324 13691838 4384402..4385916 1 NC_018650.1 COG1292 Choline-glycine betaine transporter; L-carnitine/gamma-butyrobetaine antiporter 4385916 13691838 O3M_21245 Escherichia coli O104:H4 str. 2009EL-2050 L-carnitine/gamma-butyrobetaine antiporter YP_006771870.1 4384402 D 1134782 CDS YP_006771871.1 410484325 13691839 4385947..4387089 1 NC_018650.1 COG1960 Acyl-CoA dehydrogenases; crotonobetainyl-CoA dehydrogenase 4387089 13691839 O3M_21250 Escherichia coli O104:H4 str. 2009EL-2050 crotonobetainyl-CoA dehydrogenase YP_006771871.1 4385947 D 1134782 CDS YP_006771872.1 410484326 13691840 4387218..4388435 1 NC_018650.1 COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; crotonobetainyl-CoA:carnitine CoA-transferase 4388435 13691840 O3M_21255 Escherichia coli O104:H4 str. 2009EL-2050 crotonobetainyl-CoA:carnitine CoA-transferase YP_006771872.1 4387218 D 1134782 CDS YP_006771873.1 410484327 13691841 4388509..4390062 1 NC_018650.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; crotonobetaine/carnitine-CoA ligase 4390062 caiC 13691841 caiC Escherichia coli O104:H4 str. 2009EL-2050 crotonobetaine/carnitine-CoA ligase YP_006771873.1 4388509 D 1134782 CDS YP_006771874.1 410484328 13691842 4390171..4390956 1 NC_018650.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; carnitinyl-CoA dehydratase 4390956 13691842 O3M_21265 Escherichia coli O104:H4 str. 2009EL-2050 carnitinyl-CoA dehydratase YP_006771874.1 4390171 D 1134782 CDS YP_006771875.1 410484329 13691843 4390962..4391552 1 NC_018650.1 COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; carnitine operon protein CaiE 4391552 13691843 O3M_21270 Escherichia coli O104:H4 str. 2009EL-2050 carnitine operon protein CaiE YP_006771875.1 4390962 D 1134782 CDS YP_006771876.1 410484330 13691844 complement(4391638..4392033) 1 NC_018650.1 DNA-binding transcriptional activator CaiF 4392033 13691844 O3M_21275 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator CaiF YP_006771876.1 4391638 R 1134782 CDS YP_006771877.1 410484331 13691845 complement(4392294..4395515) 1 NC_018650.1 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); carbamoyl phosphate synthase large subunit 4395515 carB 13691845 carB Escherichia coli O104:H4 str. 2009EL-2050 carbamoyl phosphate synthase large subunit YP_006771877.1 4392294 R 1134782 CDS YP_006771878.1 410484332 13691846 complement(4395533..4396681) 1 NC_018650.1 COG0505 Carbamoylphosphate synthase small subunit; carbamoyl phosphate synthase small subunit 4396681 13691846 O3M_21285 Escherichia coli O104:H4 str. 2009EL-2050 carbamoyl phosphate synthase small subunit YP_006771878.1 4395533 R 1134782 CDS YP_006771879.1 410484333 13691847 4396799..4396894 1 NC_018650.1 hypothetical protein 4396894 13691847 O3M_21290 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771879.1 4396799 D 1134782 CDS YP_006771880.1 410484334 13691848 complement(4397137..4397958) 1 NC_018650.1 COG0289 Dihydrodipicolinate reductase; dihydrodipicolinate reductase 4397958 13691848 O3M_21295 Escherichia coli O104:H4 str. 2009EL-2050 dihydrodipicolinate reductase YP_006771880.1 4397137 R 1134782 CDS YP_006771881.1 410484335 13691849 complement(4398125..4399039) 1 NC_018650.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribonucleoside hydrolase RihC 4399039 13691849 O3M_21300 Escherichia coli O104:H4 str. 2009EL-2050 ribonucleoside hydrolase RihC YP_006771881.1 4398125 R 1134782 CDS YP_006771882.1 410484336 13691850 complement(4399105..4400055) 1 NC_018650.1 COG0761 Penicillin tolerance protein; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 4400055 ispH 13691850 ispH Escherichia coli O104:H4 str. 2009EL-2050 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_006771882.1 4399105 R 1134782 CDS YP_006771883.1 410484337 13691851 complement(4400057..4400506) 1 NC_018650.1 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; FKBP-type peptidyl-prolyl cis-trans isomerase 4400506 13691851 O3M_21310 Escherichia coli O104:H4 str. 2009EL-2050 FKBP-type peptidyl-prolyl cis-trans isomerase YP_006771883.1 4400057 R 1134782 CDS YP_006771884.1 410484338 13691852 complement(4400594..4401088) 1 NC_018650.1 COG0597 Lipoprotein signal peptidase; lipoprotein signal peptidase 4401088 lspA 13691852 lspA Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein signal peptidase YP_006771884.1 4400594 R 1134782 CDS YP_006771885.1 410484339 13691853 complement(4401088..4403904) 1 NC_018650.1 COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 4403904 ileS 13691853 ileS Escherichia coli O104:H4 str. 2009EL-2050 isoleucyl-tRNA synthetase YP_006771885.1 4401088 R 1134782 CDS YP_006771886.1 410484340 13691854 complement(4403947..4404888) 1 NC_018650.1 COG0196 FAD synthase; bifunctional riboflavin kinase/FMN adenylyltransferase 4404888 13691854 O3M_21325 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional riboflavin kinase/FMN adenylyltransferase YP_006771886.1 4403947 R 1134782 CDS YP_006771887.1 410484341 13691855 complement(4404896..4405114) 1 NC_018650.1 hypothetical protein 4405114 13691855 O3M_21330 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771887.1 4404896 R 1134782 CDS YP_006771888.1 410484342 13691856 4405217..4405480 1 NC_018650.1 COG0268 Ribosomal protein S20; 30S ribosomal protein S20 4405480 rpsT 13691856 rpsT Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S20 YP_006771888.1 4405217 D 1134782 CDS YP_006771889.1 410484343 13691857 4406263..4407384 1 NC_018650.1 COG1357 Uncharacterized low-complexity proteins; T3SS effector EspX 4407384 13691857 O3M_21340 Escherichia coli O104:H4 str. 2009EL-2050 T3SS effector EspX YP_006771889.1 4406263 D 1134782 CDS YP_006771890.1 410484344 13691858 4407817..4408962 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; hypothetical protein 4408962 13691858 O3M_21345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771890.1 4407817 D 1134782 CDS YP_006771891.1 410484345 13691859 4408975..4409934 1 NC_018650.1 hypothetical protein 4409934 13691859 O3M_21350 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771891.1 4408975 D 1134782 CDS YP_006771892.1 410484346 13691860 complement(4409973..4410878) 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional activator NhaR 4410878 nhaR 13691860 nhaR Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator NhaR YP_006771892.1 4409973 R 1134782 CDS YP_006771893.1 410484347 13691861 complement(4410938..4412104) 1 NC_018650.1 COG3004 Na+/H+ antiporter; pH-dependent sodium/proton antiporter 4412104 nhaA 13691861 nhaA Escherichia coli O104:H4 str. 2009EL-2050 pH-dependent sodium/proton antiporter YP_006771893.1 4410938 R 1134782 CDS YP_006771894.1 410484348 13691862 4412633..4412842 1 NC_018650.1 regulatory protein MokC for HokC 4412842 13691862 O3M_21365 Escherichia coli O104:H4 str. 2009EL-2050 regulatory protein MokC for HokC YP_006771894.1 4412633 D 1134782 CDS YP_006771895.1 410484349 13691863 complement(4412946..4414076) 1 NC_018650.1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; chaperone protein DnaJ 4414076 13691863 O3M_21370 Escherichia coli O104:H4 str. 2009EL-2050 chaperone protein DnaJ YP_006771895.1 4412946 R 1134782 CDS YP_006771896.1 410484350 13691864 complement(4414165..4416081) 1 NC_018650.1 COG0443 Molecular chaperone; molecular chaperone DnaK 4416081 dnaK 13691864 dnaK Escherichia coli O104:H4 str. 2009EL-2050 molecular chaperone DnaK YP_006771896.1 4414165 R 1134782 CDS YP_006771897.1 410484351 13691865 4416458..4416862 1 NC_018650.1 hypothetical protein 4416862 13691865 O3M_21380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771897.1 4416458 D 1134782 CDS YP_006771898.1 410484352 13691866 4416888..4417601 1 NC_018650.1 COG4735 Uncharacterized protein conserved in bacteria; hypothetical protein 4417601 13691866 O3M_21385 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771898.1 4416888 D 1134782 CDS YP_006771899.1 410484353 13691867 4417750..4418316 1 NC_018650.1 COG1584 Predicted membrane protein; hypothetical protein 4418316 13691867 O3M_21390 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771899.1 4417750 D 1134782 CDS YP_006771900.1 410484354 13691868 complement(4418351..4418938) 1 NC_018650.1 COG0521 Molybdopterin biosynthesis enzymes; molybdenum cofactor biosynthesis protein MogA 4418938 mogA 13691868 mogA Escherichia coli O104:H4 str. 2009EL-2050 molybdenum cofactor biosynthesis protein MogA YP_006771900.1 4418351 R 1134782 CDS YP_006771901.1 410484355 13691869 complement(4419053..4420006) 1 NC_018650.1 COG0176 Transaldolase; transaldolase B 4420006 13691869 O3M_21400 Escherichia coli O104:H4 str. 2009EL-2050 transaldolase B YP_006771901.1 4419053 R 1134782 CDS YP_006771902.1 410484356 13691870 4420285..4421715 1 NC_018650.1 COG1115 Na+/alanine symporter; transporter 4421715 13691870 O3M_21405 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771902.1 4420285 D 1134782 CDS YP_006771903.1 410484357 13691871 4421785..4422561 1 NC_018650.1 COG3022 Uncharacterized protein conserved in bacteria; hypothetical protein 4422561 13691871 O3M_21410 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771903.1 4421785 D 1134782 CDS YP_006771904.1 410484358 13691872 complement(4422715..4423011) 1 NC_018650.1 hypothetical protein 4423011 13691872 O3M_21415 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771904.1 4422715 R 1134782 CDS YP_006771905.1 410484359 13691873 complement(4423225..4424511) 1 NC_018650.1 COG0498 Threonine synthase; threonine synthase 4424511 13691873 O3M_21420 Escherichia coli O104:H4 str. 2009EL-2050 threonine synthase YP_006771905.1 4423225 R 1134782 CDS YP_006771906.1 410484360 13691874 complement(4424512..4425444) 1 NC_018650.1 COG0083 Homoserine kinase; homoserine kinase 4425444 13691874 O3M_21425 Escherichia coli O104:H4 str. 2009EL-2050 homoserine kinase YP_006771906.1 4424512 R 1134782 CDS YP_006771907.1 410484361 13691875 complement(4425446..4427908) 1 NC_018650.1 COG0527 Aspartokinases; bifunctional aspartokinase I/homoserine dehydrogenase I 4427908 thrA 13691875 thrA Escherichia coli O104:H4 str. 2009EL-2050 bifunctional aspartokinase I/homoserine dehydrogenase I YP_006771907.1 4425446 R 1134782 CDS YP_006771908.1 410484362 13691876 complement(4428268..4428954) 1 NC_018650.1 COG0565 rRNA methylase; RNA methyltransferase 4428954 13691876 O3M_21435 Escherichia coli O104:H4 str. 2009EL-2050 RNA methyltransferase YP_006771908.1 4428268 R 1134782 CDS YP_006771909.1 410484363 13691877 4429590..4430306 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component response regulator 4430306 13691877 O3M_21440 Escherichia coli O104:H4 str. 2009EL-2050 two-component response regulator YP_006771909.1 4429590 D 1134782 CDS YP_006771910.1 410484364 13691878 complement(4430366..4431718) 1 NC_018650.1 COG4452 Inner membrane protein involved in colicin E2 resistance; inner membrane protein 4431718 13691878 O3M_21445 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771910.1 4430366 R 1134782 CDS YP_006771911.1 410484365 13691879 complement(4431776..4433200) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensory histidine kinase CreC 4433200 13691879 O3M_21450 Escherichia coli O104:H4 str. 2009EL-2050 sensory histidine kinase CreC YP_006771911.1 4431776 R 1134782 CDS YP_006771912.1 410484366 13691880 complement(4433200..4433889) 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding response regulator CreB 4433889 13691880 O3M_21455 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding response regulator CreB YP_006771912.1 4433200 R 1134782 CDS YP_006771913.1 410484367 13691881 complement(4433902..4434375) 1 NC_018650.1 COG3045 Uncharacterized protein conserved in bacteria; hypothetical protein 4434375 13691881 O3M_21460 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771913.1 4433902 R 1134782 CDS YP_006771914.1 410484368 13691882 4434586..4435455 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; right oriC-binding transcriptional activator 4435455 13691882 O3M_21465 Escherichia coli O104:H4 str. 2009EL-2050 right oriC-binding transcriptional activator YP_006771914.1 4434586 D 1134782 CDS YP_006771915.1 410484369 13691883 complement(4435452..4436099) 1 NC_018650.1 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 4436099 13691883 O3M_21470 Escherichia coli O104:H4 str. 2009EL-2050 phosphoglycerate mutase YP_006771915.1 4435452 R 1134782 CDS YP_006771916.1 410484370 13691884 4436151..4436663 1 NC_018650.1 COG1986 Uncharacterized conserved protein; inosine/xanthosine triphosphatase 4436663 13691884 O3M_21475 Escherichia coli O104:H4 str. 2009EL-2050 inosine/xanthosine triphosphatase YP_006771916.1 4436151 D 1134782 CDS YP_006771917.1 410484371 13691885 complement(4436705..4437031) 1 NC_018650.1 COG2973 Trp operon repressor; Trp operon repressor 4437031 13691885 O3M_21480 Escherichia coli O104:H4 str. 2009EL-2050 Trp operon repressor YP_006771917.1 4436705 R 1134782 CDS YP_006771918.1 410484372 13691886 complement(4437121..4439058) 1 NC_018650.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic murein transglycosylase 4439058 13691886 O3M_21485 Escherichia coli O104:H4 str. 2009EL-2050 lytic murein transglycosylase YP_006771918.1 4437121 R 1134782 CDS YP_006771919.1 410484373 13691887 4439269..4440936 1 NC_018650.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 4440936 13691887 O3M_21490 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006771919.1 4439269 D 1134782 CDS YP_006771920.1 410484374 13691888 complement(4441243..4442475) 1 NC_018650.1 COG1396 Predicted transcriptional regulators; bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase 4442475 13691888 O3M_21495 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase YP_006771920.1 4441243 R 1134782 CDS YP_006771921.1 410484375 13691889 complement(4442496..4443878) 1 NC_018650.1 COG1066 Predicted ATP-dependent serine protease; DNA repair protein RadA 4443878 13691889 O3M_21500 Escherichia coli O104:H4 str. 2009EL-2050 DNA repair protein RadA YP_006771921.1 4442496 R 1134782 CDS YP_006771922.1 410484376 13691890 complement(4443927..4444895) 1 NC_018650.1 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase 4444895 serB 13691890 serB Escherichia coli O104:H4 str. 2009EL-2050 phosphoserine phosphatase YP_006771922.1 4443927 R 1134782 CDS YP_006771923.1 410484377 13691891 4445001..4445645 1 NC_018650.1 COG3726 Uncharacterized membrane protein affecting hemolysin expression; hypothetical protein 4445645 13691891 O3M_21510 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771923.1 4445001 D 1134782 CDS YP_006771924.1 410484378 13691892 4445673..4446689 1 NC_018650.1 COG0095 Lipoate-protein ligase A; lipoate-protein ligase A 4446689 lplA 13691892 lplA Escherichia coli O104:H4 str. 2009EL-2050 lipoate-protein ligase A YP_006771924.1 4445673 D 1134782 CDS YP_006771925.1 410484379 13691893 4446721..4446870 1 NC_018650.1 hypothetical protein 4446870 13691893 O3M_21520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771925.1 4446721 D 1134782 CDS YP_006771926.1 410484380 13691894 complement(4447145..4447864) 1 NC_018650.1 COG0813 Purine-nucleoside phosphorylase; purine nucleoside phosphorylase 4447864 deoD 13691894 deoD Escherichia coli O104:H4 str. 2009EL-2050 purine nucleoside phosphorylase YP_006771926.1 4447145 R 1134782 CDS YP_006771927.1 410484381 13691895 complement(4447944..4449167) 1 NC_018650.1 COG1015 Phosphopentomutase; phosphopentomutase 4449167 13691895 O3M_21530 Escherichia coli O104:H4 str. 2009EL-2050 phosphopentomutase YP_006771927.1 4447944 R 1134782 CDS YP_006771928.1 410484382 13691896 complement(4449219..4450541) 1 NC_018650.1 COG0213 Thymidine phosphorylase; thymidine phosphorylase 4450541 deoA 13691896 deoA Escherichia coli O104:H4 str. 2009EL-2050 thymidine phosphorylase YP_006771928.1 4449219 R 1134782 CDS YP_006771929.1 410484383 13691897 complement(4450619..4451398) 1 NC_018650.1 COG0274 Deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase 4451398 13691897 O3M_21540 Escherichia coli O104:H4 str. 2009EL-2050 deoxyribose-phosphate aldolase YP_006771929.1 4450619 R 1134782 CDS YP_006771930.1 410484384 13691898 4451656..4453206 1 NC_018650.1 hypothetical protein 4453206 13691898 O3M_21545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771930.1 4451656 D 1134782 CDS YP_006771931.1 410484385 13691899 4453178..4454041 1 NC_018650.1 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase activating enzyme 4454041 13691899 O3M_21550 Escherichia coli O104:H4 str. 2009EL-2050 pyruvate formate lyase activating enzyme YP_006771931.1 4453178 D 1134782 CDS YP_006771932.1 410484386 13691900 complement(4454271..4455053) 1 NC_018650.1 COG0084 Mg-dependent DNase; deoxyribonuclease YjjV 4455053 13691900 O3M_21555 Escherichia coli O104:H4 str. 2009EL-2050 deoxyribonuclease YjjV YP_006771932.1 4454271 R 1134782 CDS YP_006771933.1 410484387 13691901 complement(4455050..4456123) 1 NC_018650.1 COG4667 Predicted esterase of the alpha-beta hydrolase superfamily; esterase 4456123 13691901 O3M_21560 Escherichia coli O104:H4 str. 2009EL-2050 esterase YP_006771933.1 4455050 R 1134782 CDS YP_006771934.1 410484388 13691902 complement(4456245..4456406) 1 NC_018650.1 hypothetical protein 4456406 13691902 O3M_21565 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771934.1 4456245 R 1134782 CDS YP_006771935.1 410484389 13691903 complement(4456533..4457138) 1 NC_018650.1 COG2823 Predicted periplasmic or secreted lipoprotein; hypothetical protein 4457138 13691903 O3M_21570 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771935.1 4456533 R 1134782 CDS YP_006771936.1 410484390 13691904 complement(4457531..4459120) 1 NC_018650.1 COG4108 Peptide chain release factor RF-3; peptide chain release factor 3 4459120 prfC 13691904 prfC Escherichia coli O104:H4 str. 2009EL-2050 peptide chain release factor 3 YP_006771936.1 4457531 R 1134782 CDS YP_006771937.1 410484391 13691905 complement(4459211..4459888) 1 NC_018650.1 COG1011 Predicted hydrolase (HAD superfamily); dUMP phosphatase 4459888 13691905 O3M_21580 Escherichia coli O104:H4 str. 2009EL-2050 dUMP phosphatase YP_006771937.1 4459211 R 1134782 CDS YP_006771938.1 410484392 13691906 complement(4459903..4460349) 1 NC_018650.1 COG0456 Acetyltransferases; ribosomal-protein-alanine N-acetyltransferase 4460349 rimI 13691906 rimI Escherichia coli O104:H4 str. 2009EL-2050 ribosomal-protein-alanine N-acetyltransferase YP_006771938.1 4459903 R 1134782 CDS YP_006771939.1 410484393 13691907 complement(4460318..4460731) 1 NC_018650.1 COG3050 DNA polymerase III, psi subunit; DNA polymerase III subunit psi 4460731 13691907 O3M_21590 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit psi YP_006771939.1 4460318 R 1134782 CDS YP_006771940.1 410484394 13691908 4460834..4461865 1 NC_018650.1 COG2813 16S RNA G1207 methylase RsmC; 16S ribosomal RNA m2G1207 methyltransferase 4461865 rsmC 13691908 rsmC Escherichia coli O104:H4 str. 2009EL-2050 16S ribosomal RNA m2G1207 methyltransferase YP_006771940.1 4460834 D 1134782 CDS YP_006771941.1 410484395 13691912 complement(4462535..4462771) 1 NC_018650.1 hypothetical protein 4462771 13691912 O3M_21600 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771941.1 4462535 R 1134782 CDS YP_006771942.1 410484396 13691913 4462912..4463700 1 NC_018650.1 COG4114 Uncharacterized Fe-S protein; ferric hydroximate transport ferric iron reductase 4463700 13691913 O3M_21605 Escherichia coli O104:H4 str. 2009EL-2050 ferric hydroximate transport ferric iron reductase YP_006771942.1 4462912 D 1134782 CDS YP_006771943.1 410484397 13691914 complement(4463738..4464361) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional activator BglJ 4464361 13691914 O3M_21610 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator BglJ YP_006771943.1 4463738 R 1134782 CDS YP_006771944.1 410484398 13691915 complement(4464373..4465098) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; DNA-binding transcriptional regulator 4465098 13691915 O3M_21615 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771944.1 4464373 R 1134782 CDS YP_006771945.1 410484399 13691916 4465719..4466489 1 NC_018650.1 COG2966 Uncharacterized conserved protein; hypothetical protein 4466489 13691916 O3M_21620 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771945.1 4465719 D 1134782 CDS YP_006771946.1 410484400 13691917 4466480..4466953 1 NC_018650.1 COG3610 Uncharacterized conserved protein; hypothetical protein 4466953 13691917 O3M_21625 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771946.1 4466480 D 1134782 CDS YP_006771947.1 410484401 13691918 4467060..4467599 1 NC_018650.1 primosomal protein DnaI 4467599 13691918 O3M_21630 Escherichia coli O104:H4 str. 2009EL-2050 primosomal protein DnaI YP_006771947.1 4467060 D 1134782 CDS YP_006771948.1 410484402 13691989 4467602..4468339 1 NC_018650.1 COG1484 DNA replication protein; DNA replication protein DnaC 4468339 13691989 O3M_21635 Escherichia coli O104:H4 str. 2009EL-2050 DNA replication protein DnaC YP_006771948.1 4467602 D 1134782 CDS YP_006771949.1 410484403 13691990 4468385..4468882 1 NC_018650.1 hypothetical protein 4468882 13691990 O3M_21640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771949.1 4468385 D 1134782 CDS YP_006771950.1 410484404 13691991 4469136..4471427 1 NC_018650.1 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; phosphoglycerol transferase I 4471427 13691991 O3M_21645 Escherichia coli O104:H4 str. 2009EL-2050 phosphoglycerol transferase I YP_006771950.1 4469136 D 1134782 CDS YP_006771951.1 410484405 13691992 complement(4471568..4472590) 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; oxidoreductase, Zn-dependent and NAD(P)-binding protein 4472590 13691992 O3M_21650 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase, Zn-dependent and NAD(P)-binding protein YP_006771951.1 4471568 R 1134782 CDS YP_006771952.1 410484406 13691993 4472729..4473643 1 NC_018650.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 4473643 13691993 O3M_21655 Escherichia coli O104:H4 str. 2009EL-2050 GntR family transcriptional regulator YP_006771952.1 4472729 D 1134782 CDS YP_006771953.1 410484407 13691994 4473858..4475219 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 4475219 13691994 O3M_21660 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006771953.1 4473858 D 1134782 CDS YP_006771954.1 410484408 13691995 complement(4475268..4476932) 1 NC_018650.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein I 4476932 13691995 O3M_21665 Escherichia coli O104:H4 str. 2009EL-2050 methyl-accepting chemotaxis protein I YP_006771954.1 4475268 R 1134782 CDS YP_006771955.1 410484409 13691996 4477309..4479459 1 NC_018650.1 COG1966 Carbon starvation protein, predicted membrane protein; inner membrane protein 4479459 13691996 O3M_21670 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771955.1 4477309 D 1134782 CDS YP_006771956.1 410484410 13691997 4479590..4479793 1 NC_018650.1 COG2879 Uncharacterized small protein; hypothetical protein 4479793 13691997 O3M_21675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771956.1 4479590 D 1134782 CDS YP_006771957.1 410484411 13691998 4479804..4480760 1 NC_018650.1 COG0523 Putative GTPases (G3E family); GTP-binding protein YjiA 4480760 13691998 O3M_21680 Escherichia coli O104:H4 str. 2009EL-2050 GTP-binding protein YjiA YP_006771957.1 4479804 D 1134782 CDS YP_006771958.1 410484412 13691999 complement(4480829..4482481) 1 NC_018650.1 COG1479 Uncharacterized conserved protein; hypothetical protein 4482481 13691999 O3M_21685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771958.1 4480829 R 1134782 CDS YP_006771959.1 410484413 13692000 4482759..4485191 1 NC_018650.1 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme EcoAI R protein (R.EcoAI) 4485191 13692000 O3M_21690 Escherichia coli O104:H4 str. 2009EL-2050 type I restriction enzyme EcoAI R protein (R.EcoAI) YP_006771959.1 4482759 D 1134782 CDS YP_006771960.1 410484414 13692001 4485258..4486727 1 NC_018650.1 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme EcoEI M protein (M.EcoEI) 4486727 13692001 O3M_21695 Escherichia coli O104:H4 str. 2009EL-2050 type I restriction enzyme EcoEI M protein (M.EcoEI) YP_006771960.1 4485258 D 1134782 CDS YP_006771961.1 410484415 13692002 4486727..4488463 1 NC_018650.1 COG0732 Restriction endonuclease S subunits; type I restriction enzyme EcoAI specificity protein (S protein, S.EcoAI) 4488463 13692002 O3M_21700 Escherichia coli O104:H4 str. 2009EL-2050 type I restriction enzyme EcoAI specificity protein (S protein, S.EcoAI) YP_006771961.1 4486727 D 1134782 CDS YP_006771962.1 410484416 13692003 4488684..4489025 1 NC_018650.1 endoribonuclease SymE 4489025 13692003 O3M_21705 Escherichia coli O104:H4 str. 2009EL-2050 endoribonuclease SymE YP_006771962.1 4488684 D 1134782 CDS YP_006771963.1 410484417 13692004 complement(4491262..4491426) 1 NC_018650.1 hypothetical protein 4491426 13692004 O3M_21720 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771963.1 4491262 R 1134782 CDS YP_006771964.1 410484418 13692005 4491603..4493015 1 NC_018650.1 aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; DNA-binding transcriptional regulator 4493015 13692005 O3M_21725 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006771964.1 4491603 D 1134782 CDS YP_006771965.1 410484419 13692006 complement(4493258..4494214) 1 NC_018650.1 transposase 4494214 13692006 O3M_21730 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771965.1 4493258 R 1134782 CDS YP_006771966.1 410484420 13692007 4494681..4495913 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein MdtM 4495913 13692007 O3M_21735 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein MdtM YP_006771966.1 4494681 D 1134782 CDS YP_006771967.1 410484421 13692008 4495954..4497234 1 NC_018650.1 COG2733 Predicted membrane protein; inner membrane protein 4497234 13692008 O3M_21740 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771967.1 4495954 D 1134782 CDS YP_006771968.1 410484422 13692009 4497350..4498501 1 NC_018650.1 COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; 2-hydroxyglutaryl-CoA dehydratase 4498501 13692009 O3M_21745 Escherichia coli O104:H4 str. 2009EL-2050 2-hydroxyglutaryl-CoA dehydratase YP_006771968.1 4497350 D 1134782 CDS YP_006771969.1 410484423 13692010 4498511..4499278 1 NC_018650.1 COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); hypothetical protein 4499278 13692010 O3M_21750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771969.1 4498511 D 1134782 CDS YP_006771970.1 410484424 13692011 4499275..4499532 1 NC_018650.1 hypothetical protein 4499532 13692011 O3M_21755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771970.1 4499275 D 1134782 CDS YP_006771971.1 410484425 13692012 4499486..4500457 1 NC_018650.1 COG3204 Uncharacterized protein conserved in bacteria; hypothetical protein 4500457 13692012 O3M_21760 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771971.1 4499486 D 1134782 CDS YP_006771972.1 410484426 13692013 4500525..4501703 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; inner membrane protein 4501703 13692013 O3M_21765 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006771972.1 4500525 D 1134782 CDS YP_006771973.1 410484427 13692014 complement(4501716..4502270) 1 NC_018650.1 COG1859 RNA:NAD 2'-phosphotransferase; RNA 2'-phosphotransferase 4502270 13692014 O3M_21770 Escherichia coli O104:H4 str. 2009EL-2050 RNA 2'-phosphotransferase YP_006771973.1 4501716 R 1134782 CDS YP_006771974.1 410484428 13692015 4502520..4503203 1 NC_018650.1 COG3314 Uncharacterized protein conserved in bacteria; hypothetical protein 4503203 13692015 O3M_21775 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771974.1 4502520 D 1134782 CDS YP_006771975.1 410484429 13692016 4503200..4503661 1 NC_018650.1 COG0700 Uncharacterized membrane protein; hypothetical protein 4503661 13692016 O3M_21780 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771975.1 4503200 D 1134782 CDS YP_006771976.1 410484430 13692017 4503674..4504846 1 NC_018650.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; isoaspartyl dipeptidase 4504846 13692017 O3M_21785 Escherichia coli O104:H4 str. 2009EL-2050 isoaspartyl dipeptidase YP_006771976.1 4503674 D 1134782 CDS YP_006771977.1 410484431 13692018 4504911..4505822 1 NC_018650.1 COG0583 Transcriptional regulator; cell density-dependent motility repressor 4505822 13692018 O3M_21790 Escherichia coli O104:H4 str. 2009EL-2050 cell density-dependent motility repressor YP_006771977.1 4504911 D 1134782 CDS YP_006771978.1 410484432 13692019 complement(4505815..4506207) 1 NC_018650.1 DNA replication/recombination/repair protein 4506207 iraD 13692019 iraD Escherichia coli O104:H4 str. 2009EL-2050 DNA replication/recombination/repair protein YP_006771978.1 4505815 R 1134782 CDS YP_006771979.1 410484433 13692020 4506879..4507709 1 NC_018650.1 hypothetical protein 4507709 13692020 O3M_21800 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771979.1 4506879 D 1134782 CDS YP_006771980.1 410484434 13692021 complement(4507850..4508623) 1 NC_018650.1 COG2186 Transcriptional regulators; DNA-binding transcriptional repressor UxuR 4508623 13692021 O3M_21805 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor UxuR YP_006771980.1 4507850 R 1134782 CDS YP_006771981.1 410484435 13692022 4508622..4508816 1 NC_018650.1 hypothetical protein 4508816 13692022 O3M_21810 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771981.1 4508622 D 1134782 CDS YP_006771982.1 410484436 13692023 complement(4508838..4510298) 1 NC_018650.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; D-mannonate oxidoreductase 4510298 13692023 O3M_21815 Escherichia coli O104:H4 str. 2009EL-2050 D-mannonate oxidoreductase YP_006771982.1 4508838 R 1134782 CDS YP_006771983.1 410484437 13692024 complement(4510379..4511563) 1 NC_018650.1 COG1312 D-mannonate dehydratase; mannonate dehydratase 4511563 13692024 O3M_21820 Escherichia coli O104:H4 str. 2009EL-2050 mannonate dehydratase YP_006771983.1 4510379 R 1134782 CDS YP_006771984.1 410484438 13692025 4511903..4513246 1 NC_018650.1 COG2610 H+/gluconate symporter and related permeases; fructuronate transporter 4513246 13692025 O3M_21825 Escherichia coli O104:H4 str. 2009EL-2050 fructuronate transporter YP_006771984.1 4511903 D 1134782 CDS YP_006771985.1 410484439 13692026 4513645..4513920 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; IS1 repressor protein insA 4513920 13692026 O3M_21830 Escherichia coli O104:H4 str. 2009EL-2050 IS1 repressor protein insA YP_006771985.1 4513645 D 1134782 CDS YP_006771986.1 410484440 13692027 4513839..4514342 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase InsAB' 4514342 13692027 O3M_21835 Escherichia coli O104:H4 str. 2009EL-2050 IS1 transposase InsAB' YP_006771986.1 4513839 D 1134782 CDS YP_006771987.1 410484441 13692028 complement(4514353..4515030) 1 NC_018650.1 hypothetical protein 4515030 13692028 O3M_21840 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771987.1 4514353 R 1134782 CDS YP_006771988.1 410484442 13692029 complement(4516231..4516839) 1 NC_018650.1 COG1960 Acyl-CoA dehydrogenases; hypothetical protein 4516839 13692029 O3M_21845 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771988.1 4516231 R 1134782 CDS YP_006771989.1 410484443 13692030 complement(4516928..4517134) 1 NC_018650.1 COG3311 Predicted transcriptional regulator; hypothetical protein 4517134 13692030 O3M_21850 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771989.1 4516928 R 1134782 CDS YP_006771990.1 410484444 13692031 4517275..4517541 1 NC_018650.1 hypothetical protein 4517541 13692031 O3M_21855 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771990.1 4517275 D 1134782 CDS YP_006771991.1 410484445 13692032 4517842..4518018 1 NC_018650.1 hemolysin expression modulating protein Hha 4518018 13692032 O3M_21860 Escherichia coli O104:H4 str. 2009EL-2050 hemolysin expression modulating protein Hha YP_006771991.1 4517842 D 1134782 CDS YP_006771992.1 410484446 13692033 4518759..4519328 1 NC_018650.1 hypothetical protein 4519328 13692033 O3M_21865 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771992.1 4518759 D 1134782 CDS YP_006771993.1 410484447 13692034 4519582..4519989 1 NC_018650.1 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 4519989 13692034 O3M_21870 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771993.1 4519582 D 1134782 CDS YP_006771994.1 410484448 13692035 4519977..4520411 1 NC_018650.1 hypothetical protein 4520411 13692035 O3M_21875 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771994.1 4519977 D 1134782 CDS YP_006771995.1 410484449 13692036 4520745..4521146 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; transposase, IS3 family protein 4521146 13692036 O3M_21880 Escherichia coli O104:H4 str. 2009EL-2050 transposase, IS3 family protein YP_006771995.1 4520745 D 1134782 CDS YP_006771996.1 410484450 13692037 4521143..4521490 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; transposase 4521490 13692037 O3M_21885 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771996.1 4521143 D 1134782 CDS YP_006771997.1 410484451 13692038 4521540..4522925 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; transposase 4522925 13692038 O3M_21890 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006771997.1 4521540 D 1134782 CDS YP_006771998.1 410484452 13692039 complement(4523164..4524522) 1 NC_018650.1 COG4222 Uncharacterized protein conserved in bacteria; hypothetical protein 4524522 13692039 O3M_21895 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771998.1 4523164 R 1134782 CDS YP_006771999.1 410484453 13692040 4524901..4525110 1 NC_018650.1 hypothetical protein 4525110 13692040 O3M_21900 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006771999.1 4524901 D 1134782 CDS YP_006772000.1 410484454 13692041 complement(4525273..4525530) 1 NC_018650.1 hypothetical protein 4525530 13692041 O3M_21905 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772000.1 4525273 R 1134782 CDS YP_006772001.1 410484455 13692042 4526448..4526969 1 NC_018650.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor FecI 4526969 13692042 O3M_21910 Escherichia coli O104:H4 str. 2009EL-2050 RNA polymerase sigma factor FecI YP_006772001.1 4526448 D 1134782 CDS YP_006772002.1 410484456 13692043 4526966..4527919 1 NC_018650.1 COG3712 Fe2+-dicitrate sensor, membrane component; fec operon regulator FecR 4527919 13692043 O3M_21915 Escherichia coli O104:H4 str. 2009EL-2050 fec operon regulator FecR YP_006772002.1 4526966 D 1134782 CDS YP_006772003.1 410484457 13692044 4528006..4530330 1 NC_018650.1 KpLE2 phage-like element; COG4772 Outer membrane receptor for Fe3+-dicitrate; ferric citrate outer membrane transporter 4530330 13692044 O3M_21920 Escherichia coli O104:H4 str. 2009EL-2050 ferric citrate outer membrane transporter YP_006772003.1 4528006 D 1134782 CDS YP_006772004.1 410484458 13692045 4530375..4531277 1 NC_018650.1 COG4594 ABC-type Fe3+-citrate transport system, periplasmic component; iron-dicitrate transporter substrate-binding subunit 4531277 fecB 13692045 fecB Escherichia coli O104:H4 str. 2009EL-2050 iron-dicitrate transporter substrate-binding subunit YP_006772004.1 4530375 D 1134782 CDS YP_006772005.1 410484459 13692046 4531274..4532272 1 NC_018650.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-dicitrate transporter permease subunit 4532272 fecC 13692046 fecC Escherichia coli O104:H4 str. 2009EL-2050 iron-dicitrate transporter permease subunit YP_006772005.1 4531274 D 1134782 CDS YP_006772006.1 410484460 13692047 4532269..4533225 1 NC_018650.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-dicitrate transporter subunit FecD 4533225 fecD 13692047 fecD Escherichia coli O104:H4 str. 2009EL-2050 iron-dicitrate transporter subunit FecD YP_006772006.1 4532269 D 1134782 CDS YP_006772007.1 410484461 13692048 4533226..4533993 1 NC_018650.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron-dicitrate transporter ATP-binding subunit 4533993 fecE 13692048 fecE Escherichia coli O104:H4 str. 2009EL-2050 iron-dicitrate transporter ATP-binding subunit YP_006772007.1 4533226 D 1134782 CDS YP_006772008.1 410484462 13692049 complement(4534551..4534964) 1 NC_018650.1 COG2085 Predicted dinucleotide-binding enzymes; KpLE2 phage-like element 4534964 13692049 O3M_21945 Escherichia coli O104:H4 str. 2009EL-2050 KpLE2 phage-like element YP_006772008.1 4534551 R 1134782 CDS YP_006772009.1 410484463 13692050 complement(4535459..4536982) 1 NC_018650.1 COG3344 Retron-type reverse transcriptase; group II intron encoded reverse transcriptase/maturase 4536982 13692050 O3M_21955 Escherichia coli O104:H4 str. 2009EL-2050 group II intron encoded reverse transcriptase/maturase YP_006772009.1 4535459 R 1134782 CDS YP_006772010.1 410484464 13692051 complement(4538055..4538357) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS911; transposase ORF A, IS911 4538357 13692051 O3M_21965 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS911 YP_006772010.1 4538055 R 1134782 CDS YP_006772011.1 410484465 13692052 4538564..4539385 1 NC_018650.1 COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase family protein 4539385 13692052 O3M_21970 Escherichia coli O104:H4 str. 2009EL-2050 polysaccharide deacetylase family protein YP_006772011.1 4538564 D 1134782 CDS YP_006772012.1 410484466 13692053 4539388..4540476 1 NC_018650.1 COG0438 Glycosyltransferase; Glycosyl transferase 4540476 13692053 O3M_21975 Escherichia coli O104:H4 str. 2009EL-2050 Glycosyl transferase YP_006772012.1 4539388 D 1134782 CDS YP_006772013.1 410484467 13692054 4540481..4541431 1 NC_018650.1 COG2990 Uncharacterized protein conserved in bacteria; regulator of virG protein 4541431 13692054 O3M_21980 Escherichia coli O104:H4 str. 2009EL-2050 regulator of virG protein YP_006772013.1 4540481 D 1134782 CDS YP_006772014.1 410484468 13692055 4541496..4542440 1 NC_018650.1 COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 4542440 13692055 O3M_21985 Escherichia coli O104:H4 str. 2009EL-2050 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_006772014.1 4541496 D 1134782 CDS YP_006772015.1 410484469 13692056 4543047..4543760 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; hypothetical protein 4543760 13692056 O3M_21990 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772015.1 4543047 D 1134782 CDS YP_006772016.1 410484470 13692057 4543908..4545911 1 NC_018650.1 COG1292 Choline-glycine betaine transporter; betaine-carnitine-choline transporter family member BetU 4545911 13692057 O3M_21995 Escherichia coli O104:H4 str. 2009EL-2050 betaine-carnitine-choline transporter family member BetU YP_006772016.1 4543908 D 1134782 CDS YP_006772017.1 410484471 13692058 4545974..4547251 1 NC_018650.1 COG4325 Predicted membrane protein; hypothetical protein 4547251 13692058 O3M_22000 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772017.1 4545974 D 1134782 CDS YP_006772018.1 410484472 13692059 4547497..4548153 1 NC_018650.1 COG1309 Transcriptional regulator; HTH regulator, TetR family protein 4548153 13692059 O3M_22005 Escherichia coli O104:H4 str. 2009EL-2050 HTH regulator, TetR family protein YP_006772018.1 4547497 D 1134782 CDS YP_006772019.1 410484473 13692060 4548601..4549026 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS66 transposase 4549026 13692060 O3M_22015 Escherichia coli O104:H4 str. 2009EL-2050 IS66 transposase YP_006772019.1 4548601 D 1134782 CDS YP_006772020.1 410484474 13692061 4549023..4549373 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; IS66 transposase 4549373 13692061 O3M_22020 Escherichia coli O104:H4 str. 2009EL-2050 IS66 transposase YP_006772020.1 4549023 D 1134782 CDS YP_006772021.1 410484475 13692062 4549404..4551017 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; IS element transposase 4551017 13692062 O3M_22025 Escherichia coli O104:H4 str. 2009EL-2050 IS element transposase YP_006772021.1 4549404 D 1134782 CDS YP_006772022.1 410484476 13692063 complement(4551093..4551356) 1 NC_018650.1 hypothetical protein 4551356 13692063 O3M_22030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772022.1 4551093 R 1134782 CDS YP_006772023.1 410484477 13692064 4551984..4552100 1 NC_018650.1 hypothetical protein 4552100 13692064 O3M_22035 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772023.1 4551984 D 1134782 CDS YP_006772024.1 410484478 13692065 4552101..4552199 1 NC_018650.1 acetolactate synthase 1 regulatory subunit 4552199 13692065 O3M_22040 Escherichia coli O104:H4 str. 2009EL-2050 acetolactate synthase 1 regulatory subunit YP_006772024.1 4552101 D 1134782 CDS YP_006772025.1 410484479 13692066 complement(4552201..4552983) 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; transcriptional regulator 4552983 13692066 O3M_22045 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772025.1 4552201 R 1134782 CDS YP_006772026.1 410484480 13692067 4553289..4554209 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; ribokinase sugar kinase 4554209 13692067 O3M_22050 Escherichia coli O104:H4 str. 2009EL-2050 ribokinase sugar kinase YP_006772026.1 4553289 D 1134782 CDS YP_006772027.1 410484481 13692068 4554237..4555553 1 NC_018650.1 COG0738 Fucose permease; L-fucose permease 4555553 13692068 O3M_22055 Escherichia coli O104:H4 str. 2009EL-2050 L-fucose permease YP_006772027.1 4554237 D 1134782 CDS YP_006772028.1 410484482 13692069 4555565..4556578 1 NC_018650.1 Deoxyribose specific mutarotase 4556578 13692069 O3M_22060 Escherichia coli O104:H4 str. 2009EL-2050 Deoxyribose specific mutarotase YP_006772028.1 4555565 D 1134782 CDS YP_006772029.1 410484483 13692151 complement(4557501..4558757) 1 NC_018650.1 COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC 4558757 13692151 O3M_22070 Escherichia coli O104:H4 str. 2009EL-2050 PTS system ascorbate-specific transporter subunit IIC YP_006772029.1 4557501 R 1134782 CDS YP_006772030.1 410484484 13692152 complement(4558770..4559057) 1 NC_018650.1 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system transporter subunit IIB 4559057 13692152 O3M_22075 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter subunit IIB YP_006772030.1 4558770 R 1134782 CDS YP_006772031.1 410484485 13692153 complement(4559073..4559516) 1 NC_018650.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system transporter subunit IIA 4559516 13692153 O3M_22080 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter subunit IIA YP_006772031.1 4559073 R 1134782 CDS YP_006772032.1 410484486 13692154 4559787..4560818 1 NC_018650.1 COG1609 Transcriptional regulators; transcriptional regulator 4560818 13692154 O3M_22085 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772032.1 4559787 D 1134782 CDS YP_006772033.1 410484487 13692155 complement(4561998..4562156) 1 NC_018650.1 COG0207 Thymidylate synthase; hypothetical protein 4562156 13692155 O3M_22095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772033.1 4561998 R 1134782 CDS YP_006772034.1 410484488 13692156 complement(4562588..4562809) 1 NC_018650.1 hypothetical protein 4562809 13692156 O3M_22100 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772034.1 4562588 R 1134782 CDS YP_006772035.1 410484489 13692157 complement(4562788..4562952) 1 NC_018650.1 hypothetical protein 4562952 13692157 O3M_22105 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772035.1 4562788 R 1134782 CDS YP_006772036.1 410484490 13692158 complement(4563064..4563753) 1 NC_018650.1 COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; N-acetylmannosamine-6-phosphate 2-epimerase 4563753 13692158 O3M_22110 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmannosamine-6-phosphate 2-epimerase YP_006772036.1 4563064 R 1134782 CDS YP_006772037.1 410484491 13692159 complement(4563753..4565309) 1 NC_018650.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose-specific transporter subunit IIABC 4565309 13692159 O3M_22115 Escherichia coli O104:H4 str. 2009EL-2050 PTS system glucose-specific transporter subunit IIABC YP_006772037.1 4563753 R 1134782 CDS YP_006772038.1 410484492 13692160 4565475..4566299 1 NC_018650.1 COG1737 Transcriptional regulators; transcriptional regulator 4566299 13692160 O3M_22120 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772038.1 4565475 D 1134782 CDS YP_006772039.1 410484493 13692161 complement(4566471..4566974) 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; IS1; transposase ORF B, IS1 4566974 13692161 O3M_22125 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF B, IS1 YP_006772039.1 4566471 R 1134782 CDS YP_006772040.1 410484494 13692162 complement(4566893..4567168) 1 NC_018650.1 KpLE2 phage-like element; COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA 4567168 13692162 O3M_22130 Escherichia coli O104:H4 str. 2009EL-2050 IS1 repressor protein InsA YP_006772040.1 4566893 R 1134782 CDS YP_006772041.1 410484495 13692163 4567210..4567839 1 NC_018650.1 hypothetical protein 4567839 13692163 O3M_22135 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772041.1 4567210 D 1134782 CDS YP_006772042.1 410484496 13692164 complement(4567890..4568966) 1 NC_018650.1 COG3177 Uncharacterized conserved protein; Filamentation induced by cAMP protein Fic 4568966 13692164 O3M_22140 Escherichia coli O104:H4 str. 2009EL-2050 Filamentation induced by cAMP protein Fic YP_006772042.1 4567890 R 1134782 CDS YP_006772043.1 410484497 13692165 complement(4569596..4569892) 1 NC_018650.1 COG1396 Predicted transcriptional regulators; transcriptional regulator 4569892 13692165 O3M_22145 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772043.1 4569596 R 1134782 CDS YP_006772044.1 410484498 13692166 4570860..4571063 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; hypothetical protein 4571063 13692166 O3M_22150 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772044.1 4570860 D 1134782 CDS YP_006772045.1 410484499 13692167 4570996..4571508 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase InsB IS1 4571508 13692167 O3M_22155 Escherichia coli O104:H4 str. 2009EL-2050 transposase InsB IS1 YP_006772045.1 4570996 D 1134782 CDS YP_006772046.1 410484500 13692168 4571562..4571942 1 NC_018650.1 COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); hypothetical protein 4571942 13692168 O3M_22160 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772046.1 4571562 D 1134782 CDS YP_006772047.1 410484501 13692169 4572187..4573059 1 NC_018650.1 COG3440 Predicted restriction endonuclease; hypothetical protein 4573059 13692169 O3M_22165 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772047.1 4572187 D 1134782 CDS YP_006772048.1 410484502 13692170 4573427..4573720 1 NC_018650.1 hypothetical protein 4573720 13692170 O3M_22170 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772048.1 4573427 D 1134782 CDS YP_006772049.1 410484503 13692171 4573806..4575011 1 NC_018650.1 COG4227 Antirestriction protein; hypothetical protein 4575011 13692171 O3M_22175 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772049.1 4573806 D 1134782 CDS YP_006772050.1 410484504 13692172 4575021..4576640 1 NC_018650.1 COG3481 Predicted HD-superfamily hydrolase; hypothetical protein 4576640 13692172 O3M_22180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772050.1 4575021 D 1134782 CDS YP_006772051.1 410484505 13692173 4576630..4577556 1 NC_018650.1 COG0582 Integrase; hypothetical protein 4577556 13692173 O3M_22185 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772051.1 4576630 D 1134782 CDS YP_006772052.1 410484506 13692175 4577986..4579005 1 NC_018650.1 COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase, Zn-dependent and NAD(P)-binding protein 4579005 13692175 O3M_22190 Escherichia coli O104:H4 str. 2009EL-2050 alcohol dehydrogenase, Zn-dependent and NAD(P)-binding protein YP_006772052.1 4577986 D 1134782 CDS YP_006772053.1 410484507 13692176 complement(4579009..4579572) 1 NC_018650.1 COG3265 Gluconate kinase; D-gluconate kinase 4579572 idnK 13692176 idnK Escherichia coli O104:H4 str. 2009EL-2050 D-gluconate kinase YP_006772053.1 4579009 R 1134782 CDS YP_006772054.1 410484508 13692177 4579789..4580820 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; L-idonate 5-dehydrogenase 4580820 13692177 O3M_22200 Escherichia coli O104:H4 str. 2009EL-2050 L-idonate 5-dehydrogenase YP_006772054.1 4579789 D 1134782 CDS YP_006772055.1 410484509 13692178 4580844..4581608 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); gluconate 5-dehydrogenase 4581608 13692178 O3M_22205 Escherichia coli O104:H4 str. 2009EL-2050 gluconate 5-dehydrogenase YP_006772055.1 4580844 D 1134782 CDS YP_006772056.1 410484510 13692179 4581673..4582992 1 NC_018650.1 COG2610 H+/gluconate symporter and related permeases; Gnt-II system L-idonate transporter 4582992 13692179 O3M_22210 Escherichia coli O104:H4 str. 2009EL-2050 Gnt-II system L-idonate transporter YP_006772056.1 4581673 D 1134782 CDS YP_006772057.1 410484511 13692180 4583059..4584057 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional repressor, 5-gluconate-binding protein 4584057 13692180 O3M_22215 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor, 5-gluconate-binding protein YP_006772057.1 4583059 D 1134782 CDS YP_006772058.1 410484512 13692181 4584135..4585637 1 NC_018650.1 COG0433 Predicted ATPase; ATPase 4585637 13692181 O3M_22220 Escherichia coli O104:H4 str. 2009EL-2050 ATPase YP_006772058.1 4584135 D 1134782 CDS YP_006772059.1 410484513 13692182 complement(4585756..4586838) 1 NC_018650.1 COG0795 Predicted permeases; lipopolysaccharide ABC transporter permease 4586838 13692182 O3M_22225 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide ABC transporter permease YP_006772059.1 4585756 R 1134782 CDS YP_006772060.1 410484514 13692183 complement(4586838..4587938) 1 NC_018650.1 COG0795 Predicted permeases; lipopolysaccharide ABC transporter permease LptF 4587938 13692183 O3M_22230 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide ABC transporter permease LptF YP_006772060.1 4586838 R 1134782 CDS YP_006772061.1 410484515 13692184 4588205..4589716 1 NC_018650.1 COG0260 Leucyl aminopeptidase; multifunctional aminopeptidase A 4589716 13692184 O3M_22235 Escherichia coli O104:H4 str. 2009EL-2050 multifunctional aminopeptidase A YP_006772061.1 4588205 D 1134782 CDS YP_006772062.1 410484516 13692185 4589850..4590293 1 NC_018650.1 COG2927 DNA polymerase III, chi subunit; DNA polymerase III subunit chi 4590293 13692185 O3M_22240 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III subunit chi YP_006772062.1 4589850 D 1134782 CDS YP_006772063.1 410484517 13692186 4590293..4593148 1 NC_018650.1 COG0525 Valyl-tRNA synthetase; valyl-tRNA synthetase 4593148 valS 13692186 valS Escherichia coli O104:H4 str. 2009EL-2050 valyl-tRNA synthetase YP_006772063.1 4590293 D 1134782 CDS YP_006772064.1 410484518 13692187 complement(4593204..4594400) 1 NC_018650.1 COG4269 Predicted membrane protein; hypothetical protein 4594400 13692187 O3M_22250 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772064.1 4593204 R 1134782 CDS YP_006772065.1 410484519 13692188 4594593..4595096 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 4595096 13692188 O3M_22255 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006772065.1 4594593 D 1134782 CDS YP_006772066.1 410484520 13692189 complement(4595142..4595558) 1 NC_018650.1 COG3076 Uncharacterized protein conserved in bacteria; RNase E inhibitor protein 4595558 13692189 O3M_22260 Escherichia coli O104:H4 str. 2009EL-2050 RNase E inhibitor protein YP_006772066.1 4595142 R 1134782 CDS YP_006772067.1 410484521 13692190 4595720..4596724 1 NC_018650.1 COG0078 Ornithine carbamoyltransferase; ornithine carbamoyltransferase subunit I 4596724 13692190 O3M_22265 Escherichia coli O104:H4 str. 2009EL-2050 ornithine carbamoyltransferase subunit I YP_006772067.1 4595720 D 1134782 CDS YP_006772068.1 410484522 13692191 complement(4596825..4597055) 1 NC_018650.1 hypothetical protein 4597055 13692191 O3M_22270 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772068.1 4596825 R 1134782 CDS YP_006772069.1 410484523 13692192 4597307..4597582 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; InsA 4597582 13692192 O3M_22275 Escherichia coli O104:H4 str. 2009EL-2050 InsA YP_006772069.1 4597307 D 1134782 CDS YP_006772070.1 410484524 13692193 4597628..4598005 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; InsAB 4598005 13692193 O3M_22280 Escherichia coli O104:H4 str. 2009EL-2050 InsAB YP_006772070.1 4597628 D 1134782 CDS YP_006772071.1 410484525 13692194 complement(4598016..4599164) 1 NC_018650.1 hypothetical protein 4599164 13692194 O3M_22285 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772071.1 4598016 R 1134782 CDS YP_006772072.1 410484526 13692195 complement(4599287..4599739) 1 NC_018650.1 COG2731 Beta-galactosidase, beta subunit; hypothetical protein 4599739 13692195 O3M_22290 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772072.1 4599287 R 1134782 CDS YP_006772073.1 410484527 13692196 complement(4599884..4600477) 1 NC_018650.1 COG1309 Transcriptional regulator; transcriptional regulator 4600477 13692196 O3M_22295 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772073.1 4599884 R 1134782 CDS YP_006772074.1 410484528 13692197 4600548..4601261 1 NC_018650.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 4601261 13692197 O3M_22300 Escherichia coli O104:H4 str. 2009EL-2050 oxidoreductase YP_006772074.1 4600548 D 1134782 CDS YP_006772075.1 410484529 13692198 4601392..4601787 1 NC_018650.1 COG0251 Putative translation initiation inhibitor, yjgF family; mRNA endoribonuclease 4601787 13692198 O3M_22305 Escherichia coli O104:H4 str. 2009EL-2050 mRNA endoribonuclease YP_006772075.1 4601392 D 1134782 CDS YP_006772076.1 410484530 13692199 4602011..4602202 1 NC_018650.1 pyrBI operon leader peptide 4602202 13692199 O3M_22310 Escherichia coli O104:H4 str. 2009EL-2050 pyrBI operon leader peptide YP_006772076.1 4602011 D 1134782 CDS YP_006772077.1 410484531 13692200 4602206..4603141 1 NC_018650.1 COG0540 Aspartate carbamoyltransferase, catalytic chain; aspartate carbamoyltransferase catalytic subunit 4603141 pyrB 13692200 pyrB Escherichia coli O104:H4 str. 2009EL-2050 aspartate carbamoyltransferase catalytic subunit YP_006772077.1 4602206 D 1134782 CDS YP_006772078.1 410484532 13692201 4603154..4603615 1 NC_018650.1 COG1781 Aspartate carbamoyltransferase, regulatory subunit; aspartate carbamoyltransferase regulatory subunit 4603615 13692201 O3M_22320 Escherichia coli O104:H4 str. 2009EL-2050 aspartate carbamoyltransferase regulatory subunit YP_006772078.1 4603154 D 1134782 CDS YP_006772079.1 410484533 13692202 4603688..4604074 1 NC_018650.1 COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 4604074 13692202 O3M_22325 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772079.1 4603688 D 1134782 CDS YP_006772080.1 410484534 13692203 4604351..4605331 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; IS621 transposase 4605331 13692203 O3M_22330 Escherichia coli O104:H4 str. 2009EL-2050 IS621 transposase YP_006772080.1 4604351 D 1134782 CDS YP_006772081.1 410484535 13692204 complement(4605559..4608255) 1 NC_018650.1 COG0474 Cation transport ATPase; magnesium-transporting ATPase MgtA 4608255 13692204 O3M_22335 Escherichia coli O104:H4 str. 2009EL-2050 magnesium-transporting ATPase MgtA YP_006772081.1 4605559 R 1134782 CDS YP_006772082.1 410484536 13692205 4608634..4609581 1 NC_018650.1 COG1609 Transcriptional regulators; trehalose repressor 4609581 treR 13692205 treR Escherichia coli O104:H4 str. 2009EL-2050 trehalose repressor YP_006772082.1 4608634 D 1134782 CDS YP_006772083.1 410484537 13692206 4609703..4611121 1 NC_018650.1 COG1264 Phosphotransferase system IIB components; PTS system trehalose(maltose)-specific transporter subunit IIBC 4611121 13692206 O3M_22345 Escherichia coli O104:H4 str. 2009EL-2050 PTS system trehalose(maltose)-specific transporter subunit IIBC YP_006772083.1 4609703 D 1134782 CDS YP_006772084.1 410484538 13692207 4611171..4612826 1 NC_018650.1 COG0366 Glycosidases; trehalose-6-phosphate hydrolase 4612826 13692207 O3M_22350 Escherichia coli O104:H4 str. 2009EL-2050 trehalose-6-phosphate hydrolase YP_006772084.1 4611171 D 1134782 CDS YP_006772085.1 410484539 13692208 4613229..4615367 1 NC_018650.1 COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; anaerobic ribonucleoside triphosphate reductase 4615367 13692208 O3M_22355 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic ribonucleoside triphosphate reductase YP_006772085.1 4613229 D 1134782 CDS YP_006772086.1 410484540 13692209 4615525..4615989 1 NC_018650.1 COG0602 Organic radical activating enzymes; anaerobic ribonucleotide reductase-activating protein 4615989 nrdG 13692209 nrdG Escherichia coli O104:H4 str. 2009EL-2050 anaerobic ribonucleotide reductase-activating protein YP_006772086.1 4615525 D 1134782 CDS YP_006772087.1 410484541 13692210 complement(4616034..4616420) 1 NC_018650.1 COG3783 Soluble cytochrome b562; cytochrome b562 4616420 13692210 O3M_22365 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome b562 YP_006772087.1 4616034 R 1134782 CDS YP_006772088.1 410484542 13692211 complement(4616603..4617943) 1 NC_018650.1 COG0312 Predicted Zn-dependent proteases and their inactivated homologs; peptidase PmbA 4617943 13692211 O3M_22370 Escherichia coli O104:H4 str. 2009EL-2050 peptidase PmbA YP_006772088.1 4616603 R 1134782 CDS YP_006772089.1 410484543 13692212 4618049..4618600 1 NC_018650.1 COG3028 Uncharacterized protein conserved in bacteria; hypothetical protein 4618600 13692212 O3M_22375 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772089.1 4618049 D 1134782 CDS YP_006772090.1 410484544 13692213 complement(4618751..4620124) 1 NC_018650.1 COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4620124 13692213 O3M_22380 Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_006772090.1 4618751 R 1134782 CDS YP_006772091.1 410484545 13692214 4620300..4621298 1 NC_018650.1 COG0158 Fructose-1,6-bisphosphatase; fructose-1,6-bisphosphatase 4621298 13692214 O3M_22385 Escherichia coli O104:H4 str. 2009EL-2050 fructose-1,6-bisphosphatase YP_006772091.1 4620300 D 1134782 CDS YP_006772092.1 410484546 13692215 complement(4621331..4622326) 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; inner membrane ABC transporter permease YjfF 4622326 13692215 O3M_22390 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane ABC transporter permease YjfF YP_006772092.1 4621331 R 1134782 CDS YP_006772093.1 410484547 13692216 complement(4622313..4623335) 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease 4623335 13692216 O3M_22395 Escherichia coli O104:H4 str. 2009EL-2050 sugar ABC transporter permease YP_006772093.1 4622313 R 1134782 CDS YP_006772094.1 410484548 13692217 complement(4623349..4624851) 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATP-binding protein 4624851 13692217 O3M_22400 Escherichia coli O104:H4 str. 2009EL-2050 sugar ABC transporter ATP-binding protein YP_006772094.1 4623349 R 1134782 CDS YP_006772095.1 410484549 13692218 complement(4625161..4626117) 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; sugar transporter subunit 4626117 13692218 O3M_22405 Escherichia coli O104:H4 str. 2009EL-2050 sugar transporter subunit YP_006772095.1 4625161 R 1134782 CDS YP_006772096.1 410484550 13692219 4626427..4626957 1 NC_018650.1 COG0221 Inorganic pyrophosphatase; inorganic pyrophosphatase 4626957 13692219 O3M_22410 Escherichia coli O104:H4 str. 2009EL-2050 inorganic pyrophosphatase YP_006772096.1 4626427 D 1134782 CDS YP_006772097.1 410484551 13692220 complement(4627037..4627387) 1 NC_018650.1 COG2337 Growth inhibitor; toxin ChpB 4627387 13692220 O3M_22415 Escherichia coli O104:H4 str. 2009EL-2050 toxin ChpB YP_006772097.1 4627037 R 1134782 CDS YP_006772098.1 410484552 13692221 complement(4627381..4627632) 1 NC_018650.1 COG2336 Growth regulator; antitoxin ChpS 4627632 13692221 O3M_22420 Escherichia coli O104:H4 str. 2009EL-2050 antitoxin ChpS YP_006772098.1 4627381 R 1134782 CDS YP_006772099.1 410484553 13692222 complement(4627844..4628185) 1 NC_018650.1 COG2105 Uncharacterized conserved protein; hypothetical protein 4628185 13692222 O3M_22425 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772099.1 4627844 R 1134782 CDS YP_006772100.1 410484554 13692223 complement(4628188..4631967) 1 NC_018650.1 COG2911 Uncharacterized protein conserved in bacteria; hypothetical protein 4631967 13692223 O3M_22430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772100.1 4628188 R 1134782 CDS YP_006772101.1 410484555 13692224 complement(4631964..4633697) 1 NC_018650.1 COG0729 Outer membrane protein; surface antigen 4633697 13692224 O3M_22435 Escherichia coli O104:H4 str. 2009EL-2050 surface antigen YP_006772101.1 4631964 R 1134782 CDS YP_006772102.1 410484556 13692225 complement(4633667..4633795) 1 NC_018650.1 COG1131 ABC-type multidrug transport system, ATPase component; hypothetical protein 4633795 13692225 O3M_22440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772102.1 4633667 R 1134782 CDS YP_006772103.1 410484557 13692226 4633903..4634541 1 NC_018650.1 COG0225 Peptide methionine sulfoxide reductase; methionine sulfoxide reductase A 4634541 13692226 O3M_22445 Escherichia coli O104:H4 str. 2009EL-2050 methionine sulfoxide reductase A YP_006772103.1 4633903 D 1134782 CDS YP_006772104.1 410484558 13692227 4634864..4636207 1 NC_018650.1 COG1253 Hemolysins and related proteins containing CBS domains; inner membrane protein 4636207 13692227 O3M_22450 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006772104.1 4634864 D 1134782 CDS YP_006772105.1 410484559 13692228 complement(4636269..4636475) 1 NC_018650.1 COG1117 ABC-type phosphate transport system, ATPase component; hypothetical protein 4636475 13692228 O3M_22455 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772105.1 4636269 R 1134782 CDS YP_006772106.1 410484560 13692229 4636800..4637357 1 NC_018650.1 COG3054 Predicted transcriptional regulator; transcriptional regulator 4637357 13692229 O3M_22460 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772106.1 4636800 D 1134782 CDS YP_006772107.1 410484561 13692230 complement(4637347..4638087) 1 NC_018650.1 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; adenosine-3'(2'),5'-bisphosphate nucleotidase 4638087 13692230 O3M_22465 Escherichia coli O104:H4 str. 2009EL-2050 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_006772107.1 4637347 R 1134782 CDS YP_006772108.1 410484562 13692231 4638277..4640220 1 NC_018650.1 COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase 4640220 cpdB 13692231 cpdB Escherichia coli O104:H4 str. 2009EL-2050 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase YP_006772108.1 4638277 D 1134782 CDS YP_006772109.1 410484563 13692313 complement(4640349..4640729) 1 NC_018650.1 COG1733 Predicted transcriptional regulators; hypothetical protein 4640729 13692313 O3M_22475 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772109.1 4640349 R 1134782 CDS YP_006772110.1 410484564 13692314 4640818..4641678 1 NC_018650.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD(P)H:quinone oxidoreductase 4641678 13692314 O3M_22480 Escherichia coli O104:H4 str. 2009EL-2050 NAD(P)H:quinone oxidoreductase YP_006772110.1 4640818 D 1134782 CDS YP_006772111.1 410484565 13692315 4641786..4642751 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; inner membrane protein 4642751 13692315 O3M_22485 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006772111.1 4641786 D 1134782 CDS YP_006772112.1 410484566 13692316 4642859..4643521 1 NC_018650.1 COG2846 Regulator of cell morphogenesis and NO signaling; iron-sulfur cluster repair di-iron protein 4643521 13692316 O3M_22490 Escherichia coli O104:H4 str. 2009EL-2050 iron-sulfur cluster repair di-iron protein YP_006772112.1 4642859 D 1134782 CDS YP_006772113.1 410484567 13692317 complement(4643566..4644978) 1 NC_018650.1 COG1113 Gamma-aminobutyrate permease and related permeases; D-alanine/D-serine/glycine permease 4644978 13692317 O3M_22495 Escherichia coli O104:H4 str. 2009EL-2050 D-alanine/D-serine/glycine permease YP_006772113.1 4643566 R 1134782 CDS YP_006772114.1 410484568 13692318 complement(4645287..4645907) 1 NC_018650.1 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; peptidyl-prolyl cis-trans isomerase 4645907 13692318 O3M_22500 Escherichia coli O104:H4 str. 2009EL-2050 peptidyl-prolyl cis-trans isomerase YP_006772114.1 4645287 R 1134782 CDS YP_006772115.1 410484569 13692319 4646126..4646764 1 NC_018650.1 COG3061 Cell envelope opacity-associated protein A; cell envelope opacity-associated protein 4646764 13692319 O3M_22505 Escherichia coli O104:H4 str. 2009EL-2050 cell envelope opacity-associated protein YP_006772115.1 4646126 D 1134782 CDS YP_006772116.1 410484570 13692320 complement(4646899..4648107) 1 NC_018650.1 COG0675 Transposase and inactivated derivatives; transposase 4648107 13692320 O3M_22510 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772116.1 4646899 R 1134782 CDS YP_006772117.1 410484571 13692321 4648115..4648546 1 NC_018650.1 COG1943 Transposase and inactivated derivatives; transposase 4648546 13692321 O3M_22515 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772117.1 4648115 D 1134782 CDS YP_006772118.1 410484572 13692322 4649169..4649963 1 NC_018650.1 hypothetical protein 4649963 13692322 O3M_22520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772118.1 4649169 D 1134782 CDS YP_006772119.1 410484573 13692323 complement(4650034..4650483) 1 NC_018650.1 COG0359 Ribosomal protein L9; 50S ribosomal protein L9 4650483 rplI 13692323 rplI Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L9 YP_006772119.1 4650034 R 1134782 CDS YP_006772120.1 410484574 13692324 complement(4650525..4650752) 1 NC_018650.1 COG0238 Ribosomal protein S18; 30S ribosomal protein S18 4650752 rpsR 13692324 rpsR Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S18 YP_006772120.1 4650525 R 1134782 CDS YP_006772121.1 410484575 13692325 complement(4650757..4651071) 1 NC_018650.1 COG2965 Primosomal replication protein N; primosomal replication protein N 4651071 13692325 O3M_22535 Escherichia coli O104:H4 str. 2009EL-2050 primosomal replication protein N YP_006772121.1 4650757 R 1134782 CDS YP_006772122.1 410484576 13692326 complement(4651078..4651473) 1 NC_018650.1 COG0360 Ribosomal protein S6; 30S ribosomal protein S6 4651473 rpsF 13692326 rpsF Escherichia coli O104:H4 str. 2009EL-2050 30S ribosomal protein S6 YP_006772122.1 4651078 R 1134782 CDS YP_006772123.1 410484577 13692327 4651800..4652075 1 NC_018650.1 hypothetical protein 4652075 13692327 O3M_22545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772123.1 4651800 D 1134782 CDS YP_006772124.1 410484578 13692328 complement(4652150..4652701) 1 NC_018650.1 COG3477 Predicted periplasmic/secreted protein; inner membrane protein yagU 4652701 13692328 O3M_22550 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein yagU YP_006772124.1 4652150 R 1134782 CDS YP_006772125.1 410484579 13692329 complement(4652798..4653484) 1 NC_018650.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase 4653484 sgaE 13692329 sgaE Escherichia coli O104:H4 str. 2009EL-2050 L-ribulose-5-phosphate 4-epimerase YP_006772125.1 4652798 R 1134782 CDS YP_006772126.1 410484580 13692330 complement(4653484..4654338) 1 NC_018650.1 COG3623 Putative L-xylulose-5-phosphate 3-epimerase; L-xylulose 5-phosphate 3-epimerase 4654338 13692330 O3M_22560 Escherichia coli O104:H4 str. 2009EL-2050 L-xylulose 5-phosphate 3-epimerase YP_006772126.1 4653484 R 1134782 CDS YP_006772127.1 410484581 13692331 complement(4654348..4654998) 1 NC_018650.1 COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-keto-L-gulonate-6-phosphate decarboxylase 4654998 ulaD 13692331 ulaD Escherichia coli O104:H4 str. 2009EL-2050 3-keto-L-gulonate-6-phosphate decarboxylase YP_006772127.1 4654348 R 1134782 CDS YP_006772128.1 410484582 13692332 complement(4655012..4655476) 1 NC_018650.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system L-ascorbate-specific transporter subunit IIA 4655476 13692332 O3M_22570 Escherichia coli O104:H4 str. 2009EL-2050 PTS system L-ascorbate-specific transporter subunit IIA YP_006772128.1 4655012 R 1134782 CDS YP_006772129.1 410484583 13692333 complement(4655486..4655791) 1 NC_018650.1 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system L-ascorbate-specific transporter subunit IIB 4655791 13692333 O3M_22575 Escherichia coli O104:H4 str. 2009EL-2050 PTS system L-ascorbate-specific transporter subunit IIB YP_006772129.1 4655486 R 1134782 CDS YP_006772130.1 410484584 13692334 complement(4655807..4657204) 1 NC_018650.1 COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC 4657204 ulaA 13692334 ulaA Escherichia coli O104:H4 str. 2009EL-2050 PTS system ascorbate-specific transporter subunit IIC YP_006772130.1 4655807 R 1134782 CDS YP_006772131.1 410484585 13692335 4657559..4658623 1 NC_018650.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; L-ascorbate 6-phosphate lactonase 4658623 13692335 O3M_22585 Escherichia coli O104:H4 str. 2009EL-2050 L-ascorbate 6-phosphate lactonase YP_006772131.1 4657559 D 1134782 CDS YP_006772132.1 410484586 13692336 4658731..4659486 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; transcriptional repressor UlaR 4659486 13692336 O3M_22590 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional repressor UlaR YP_006772132.1 4658731 D 1134782 CDS YP_006772133.1 410484587 13692337 complement(4659483..4660232) 1 NC_018650.1 COG1073 Hydrolases of the alpha/beta superfamily; esterase 4660232 13692337 O3M_22595 Escherichia coli O104:H4 str. 2009EL-2050 esterase YP_006772133.1 4659483 R 1134782 CDS YP_006772134.1 410484588 13692338 4660414..4660743 1 NC_018650.1 biofilm stress and motility protein A 4660743 13692338 O3M_22600 Escherichia coli O104:H4 str. 2009EL-2050 biofilm stress and motility protein A YP_006772134.1 4660414 D 1134782 CDS YP_006772135.1 410484589 13692339 4660892..4661167 1 NC_018650.1 hypothetical protein 4661167 13692339 O3M_22605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772135.1 4660892 D 1134782 CDS YP_006772136.1 410484590 13692340 complement(4661284..4662909) 1 NC_018650.1 COG1960 Acyl-CoA dehydrogenases; isovaleryl CoA dehydrogenase 4662909 13692340 O3M_22610 Escherichia coli O104:H4 str. 2009EL-2050 isovaleryl CoA dehydrogenase YP_006772136.1 4661284 R 1134782 CDS YP_006772137.1 410484591 13692341 complement(4662993..4664156) 1 NC_018650.1 COG0754 Glutathionylspermidine synthase; synthetase/amidase 4664156 13692341 O3M_22615 Escherichia coli O104:H4 str. 2009EL-2050 synthetase/amidase YP_006772137.1 4662993 R 1134782 CDS YP_006772138.1 410484592 13692342 complement(4664159..4664797) 1 NC_018650.1 hypothetical protein 4664797 13692342 O3M_22620 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772138.1 4664159 R 1134782 CDS YP_006772139.1 410484593 13692343 complement(4664807..4665040) 1 NC_018650.1 COG3766 Predicted membrane protein; inner membrane protein 4665040 13692343 O3M_22625 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006772139.1 4664807 R 1134782 CDS YP_006772140.1 410484594 13692344 complement(4665095..4665205) 1 NC_018650.1 COG3766 Predicted membrane protein; inner membrane protein 4665205 13692344 O3M_22630 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006772140.1 4665095 R 1134782 CDS YP_006772141.1 410484595 13692345 complement(4665223..4665882) 1 NC_018650.1 hypothetical protein 4665882 13692345 O3M_22635 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772141.1 4665223 R 1134782 CDS YP_006772142.1 410484596 13692346 complement(4665933..4666631) 1 NC_018650.1 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription; transcriptional regulator effector protein 4666631 13692346 O3M_22640 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator effector protein YP_006772142.1 4665933 R 1134782 CDS YP_006772143.1 410484597 13692347 complement(4666650..4667051) 1 NC_018650.1 COG3789 Uncharacterized protein conserved in bacteria; hypothetical protein 4667051 13692347 O3M_22645 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772143.1 4666650 R 1134782 CDS YP_006772144.1 410484598 13692348 complement(4667178..4667909) 1 NC_018650.1 COG0566 rRNA methylases; 23S rRNA (guanosine-2'-O-)-methyltransferase 4667909 13692348 O3M_22650 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA (guanosine-2'-O-)-methyltransferase YP_006772144.1 4667178 R 1134782 CDS YP_006772145.1 410484599 13692349 complement(4668089..4670530) 1 NC_018650.1 COG0557 Exoribonuclease R; exoribonuclease R 4670530 13692349 O3M_22655 Escherichia coli O104:H4 str. 2009EL-2050 exoribonuclease R YP_006772145.1 4668089 R 1134782 CDS YP_006772146.1 410484600 13692350 complement(4670569..4670994) 1 NC_018650.1 COG1959 Predicted transcriptional regulator; transcriptional repressor NsrR 4670994 13692350 O3M_22660 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional repressor NsrR YP_006772146.1 4670569 R 1134782 CDS YP_006772147.1 410484601 13692351 complement(4671199..4672497) 1 NC_018650.1 COG0104 Adenylosuccinate synthase; adenylosuccinate synthetase 4672497 13692351 O3M_22665 Escherichia coli O104:H4 str. 2009EL-2050 adenylosuccinate synthetase YP_006772147.1 4671199 R 1134782 CDS YP_006772148.1 410484602 13692352 complement(4672601..4672798) 1 NC_018650.1 COG3242 Uncharacterized protein conserved in bacteria; hypothetical protein 4672798 13692352 O3M_22670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772148.1 4672601 R 1134782 CDS YP_006772149.1 410484603 13692353 complement(4672880..4673884) 1 NC_018650.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; FtsH protease regulator HflC 4673884 13692353 O3M_22675 Escherichia coli O104:H4 str. 2009EL-2050 FtsH protease regulator HflC YP_006772149.1 4672880 R 1134782 CDS YP_006772150.1 410484604 13692354 complement(4673887..4675146) 1 NC_018650.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; FtsH protease regulator HflK 4675146 13692354 O3M_22680 Escherichia coli O104:H4 str. 2009EL-2050 FtsH protease regulator HflK YP_006772150.1 4673887 R 1134782 CDS YP_006772151.1 410484605 13692355 complement(4675232..4676512) 1 NC_018650.1 COG2262 GTPases; GTPase HflX 4676512 13692355 O3M_22685 Escherichia coli O104:H4 str. 2009EL-2050 GTPase HflX YP_006772151.1 4675232 R 1134782 CDS YP_006772152.1 410484606 13692356 complement(4676589..4676897) 1 NC_018650.1 COG1923 Uncharacterized host factor I protein; RNA-binding protein Hfq 4676897 hfq 13692356 hfq Escherichia coli O104:H4 str. 2009EL-2050 RNA-binding protein Hfq YP_006772152.1 4676589 R 1134782 CDS YP_006772153.1 410484607 13692357 complement(4676983..4677933) 1 NC_018650.1 COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA delta(2)-isopentenylpyrophosphate transferase 4677933 miaA 13692357 miaA Escherichia coli O104:H4 str. 2009EL-2050 tRNA delta(2)-isopentenylpyrophosphate transferase YP_006772153.1 4676983 R 1134782 CDS YP_006772154.1 410484608 13692358 complement(4677926..4679773) 1 NC_018650.1 COG0323 DNA mismatch repair enzyme (predicted ATPase); DNA mismatch repair protein 4679773 mutL 13692358 mutL Escherichia coli O104:H4 str. 2009EL-2050 DNA mismatch repair protein YP_006772154.1 4677926 R 1134782 CDS YP_006772155.1 410484609 13692359 complement(4679783..4681120) 1 NC_018650.1 COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-l-alanine amidase II 4681120 13692359 O3M_22705 Escherichia coli O104:H4 str. 2009EL-2050 N-acetylmuramoyl-l-alanine amidase II YP_006772155.1 4679783 R 1134782 CDS YP_006772156.1 410484610 13692360 complement(4681139..4681600) 1 NC_018650.1 COG0802 Predicted ATPase or kinase; ADP-binding protein 4681600 13692360 O3M_22710 Escherichia coli O104:H4 str. 2009EL-2050 ADP-binding protein YP_006772156.1 4681139 R 1134782 CDS YP_006772157.1 410484611 13692361 complement(4681572..4683119) 1 NC_018650.1 COG0062 Uncharacterized conserved protein; carbohydrate kinase 4683119 13692361 O3M_22715 Escherichia coli O104:H4 str. 2009EL-2050 carbohydrate kinase YP_006772157.1 4681572 R 1134782 CDS YP_006772158.1 410484612 13692362 4683118..4684257 1 NC_018650.1 COG1600 Uncharacterized Fe-S protein; Fe-S electron transport protein 4684257 13692362 O3M_22720 Escherichia coli O104:H4 str. 2009EL-2050 Fe-S electron transport protein YP_006772158.1 4683118 D 1134782 CDS YP_006772159.1 410484613 13692366 complement(4685036..4685581) 1 NC_018650.1 COG1949 Oligoribonuclease (3'->5' exoribonuclease); oligoribonuclease 4685581 13692366 O3M_22725 Escherichia coli O104:H4 str. 2009EL-2050 oligoribonuclease YP_006772159.1 4685036 R 1134782 CDS YP_006772160.1 410484614 13692367 4685676..4686728 1 NC_018650.1 COG1162 Predicted GTPases; GTPase RsgA 4686728 13692367 O3M_22730 Escherichia coli O104:H4 str. 2009EL-2050 GTPase RsgA YP_006772160.1 4685676 D 1134782 CDS YP_006772161.1 410484615 13692368 4686825..4687793 1 NC_018650.1 COG0688 Phosphatidylserine decarboxylase; phosphatidylserine decarboxylase 4687793 psd 13692368 psd Escherichia coli O104:H4 str. 2009EL-2050 phosphatidylserine decarboxylase YP_006772161.1 4686825 D 1134782 CDS YP_006772162.1 410484616 13692369 4687815..4691138 1 NC_018650.1 COG3264 Small-conductance mechanosensitive channel; mechanosensitive channel protein 4691138 13692369 O3M_22740 Escherichia coli O104:H4 str. 2009EL-2050 mechanosensitive channel protein YP_006772162.1 4687815 D 1134782 CDS YP_006772163.1 410484617 13692370 complement(4691167..4691481) 1 NC_018650.1 hypothetical protein 4691481 13692370 O3M_22745 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772163.1 4691167 R 1134782 CDS YP_006772164.1 410484618 13692371 complement(4691478..4691792) 1 NC_018650.1 hypothetical protein 4691792 13692371 O3M_22750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772164.1 4691478 R 1134782 CDS YP_006772165.1 410484619 13692372 complement(4691844..4693346) 1 NC_018650.1 COG0531 Amino acid transporters; inner membrane transporter YjeM 4693346 13692372 O3M_22755 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane transporter YjeM YP_006772165.1 4691844 R 1134782 CDS YP_006772166.1 410484620 13692373 complement(4693565..4694542) 1 NC_018650.1 COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II); poxB regulator PoxA 4694542 13692373 O3M_22760 Escherichia coli O104:H4 str. 2009EL-2050 poxB regulator PoxA YP_006772166.1 4693565 R 1134782 CDS YP_006772167.1 410484621 13692374 4694867..4696675 1 NC_018650.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; fumarate reductase flavoprotein subunit 4696675 13692374 O3M_22765 Escherichia coli O104:H4 str. 2009EL-2050 fumarate reductase flavoprotein subunit YP_006772167.1 4694867 D 1134782 CDS YP_006772168.1 410484622 13692375 4696668..4697402 1 NC_018650.1 COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; fumarate reductase iron-sulfur subunit 4697402 13692375 O3M_22770 Escherichia coli O104:H4 str. 2009EL-2050 fumarate reductase iron-sulfur subunit YP_006772168.1 4696668 D 1134782 CDS YP_006772169.1 410484623 13692376 4697413..4697808 1 NC_018650.1 COG3029 Fumarate reductase subunit C; fumarate reductase subunit C 4697808 13692376 O3M_22775 Escherichia coli O104:H4 str. 2009EL-2050 fumarate reductase subunit C YP_006772169.1 4697413 D 1134782 CDS YP_006772170.1 410484624 13692377 4697819..4698178 1 NC_018650.1 COG3080 Fumarate reductase subunit D; fumarate reductase subunit D 4698178 13692377 O3M_22780 Escherichia coli O104:H4 str. 2009EL-2050 fumarate reductase subunit D YP_006772170.1 4697819 D 1134782 CDS YP_006772171.1 410484625 13692378 4698241..4699374 1 NC_018650.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase/D-alanine carboxypeptidase 4699374 ampC 13692378 ampC Escherichia coli O104:H4 str. 2009EL-2050 beta-lactamase/D-alanine carboxypeptidase YP_006772171.1 4698241 D 1134782 CDS YP_006772172.1 410484626 13692379 4699463..4699996 1 NC_018650.1 COG3040 Bacterial lipocalin; outer membrane lipoprotein Blc 4699996 13692379 O3M_22790 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane lipoprotein Blc YP_006772172.1 4699463 D 1134782 CDS YP_006772173.1 410484627 13692380 complement(4699993..4700310) 1 NC_018650.1 COG2076 Membrane transporters of cations and cationic drugs; suppresser of groEL 4700310 13692380 O3M_22795 Escherichia coli O104:H4 str. 2009EL-2050 suppresser of groEL YP_006772173.1 4699993 R 1134782 CDS YP_006772174.1 410484628 13692381 complement(4700485..4700631) 1 NC_018650.1 COG5510 Predicted small secreted protein; entericidin B membrane lipoprotein 4700631 13692381 O3M_22800 Escherichia coli O104:H4 str. 2009EL-2050 entericidin B membrane lipoprotein YP_006772174.1 4700485 R 1134782 CDS YP_006772175.1 410484629 13692382 complement(4700742..4700867) 1 NC_018650.1 entericidin A 4700867 13692382 O3M_22805 Escherichia coli O104:H4 str. 2009EL-2050 entericidin A YP_006772175.1 4700742 R 1134782 CDS YP_006772176.1 410484630 13692383 complement(4700919..4701485) 1 NC_018650.1 COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); elongation factor P 4701485 13692383 O3M_22810 Escherichia coli O104:H4 str. 2009EL-2050 elongation factor P YP_006772176.1 4700919 R 1134782 CDS YP_006772177.1 410484631 13692384 4701527..4702555 1 NC_018650.1 COG1509 Lysine 2,3-aminomutase; lysine aminomutase 4702555 13692384 O3M_22815 Escherichia coli O104:H4 str. 2009EL-2050 lysine aminomutase YP_006772177.1 4701527 D 1134782 CDS YP_006772178.1 410484632 13692385 4702945..4703814 1 NC_018650.1 COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase); hypothetical protein 4703814 13692385 O3M_22820 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772178.1 4702945 D 1134782 CDS YP_006772179.1 410484633 13692386 complement(4704017..4704370) 1 NC_018650.1 hypothetical protein 4704370 13692386 O3M_22825 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772179.1 4704017 R 1134782 CDS YP_006772180.1 410484634 13692387 complement(4704508..4706154) 1 NC_018650.1 COG0459 Chaperonin GroEL (HSP60 family); chaperonin GroEL 4706154 groEL 13692387 groEL Escherichia coli O104:H4 str. 2009EL-2050 chaperonin GroEL YP_006772180.1 4704508 R 1134782 CDS YP_006772181.1 410484635 13692388 complement(4706198..4706491) 1 NC_018650.1 COG0234 Co-chaperonin GroES (HSP10); co-chaperonin GroES 4706491 groES 13692388 groES Escherichia coli O104:H4 str. 2009EL-2050 co-chaperonin GroES YP_006772181.1 4706198 R 1134782 CDS YP_006772182.1 410484636 13692389 4706767..4708023 1 NC_018650.1 COG0531 Amino acid transporters; transporter 4708023 13692389 O3M_22840 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772182.1 4706767 D 1134782 CDS YP_006772183.1 410484637 13692390 complement(4708039..4708515) 1 NC_018650.1 COG3030 Protein affecting phage T7 exclusion by the F plasmid; phage T7 F exclusion suppressor FxsA 4708515 fxsA 13692390 fxsA Escherichia coli O104:H4 str. 2009EL-2050 phage T7 F exclusion suppressor FxsA YP_006772183.1 4708039 R 1134782 CDS YP_006772184.1 410484638 13692391 4708852..4710288 1 NC_018650.1 COG1027 Aspartate ammonia-lyase; aspartate ammonia-lyase 4710288 aspA 13692391 aspA Escherichia coli O104:H4 str. 2009EL-2050 aspartate ammonia-lyase YP_006772184.1 4708852 D 1134782 CDS YP_006772185.1 410484639 13692392 4710406..4711707 1 NC_018650.1 COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 4711707 13692392 O3M_22855 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic C4-dicarboxylate transporter YP_006772185.1 4710406 D 1134782 CDS YP_006772186.1 410484640 13692393 4711823..4712161 1 NC_018650.1 COG1324 Uncharacterized protein involved in tolerance to divalent cations; divalent-cation tolerance protein CutA 4712161 13692393 O3M_22860 Escherichia coli O104:H4 str. 2009EL-2050 divalent-cation tolerance protein CutA YP_006772186.1 4711823 D 1134782 CDS YP_006772187.1 410484641 13692475 4712137..4713834 1 NC_018650.1 COG4232 Thiol:disulfide interchange protein; thiol:disulfide interchange protein 4713834 dipZ 13692475 dipZ Escherichia coli O104:H4 str. 2009EL-2050 thiol:disulfide interchange protein YP_006772187.1 4712137 D 1134782 CDS YP_006772188.1 410484642 13692476 4713871..4714446 1 NC_018650.1 COG1309 Transcriptional regulator; transcriptional regulator 4714446 13692476 O3M_22870 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772188.1 4713871 D 1134782 CDS YP_006772189.1 410484643 13692478 4714826..4716088 1 NC_018650.1 COG0582 Integrase; Prophage integrase 4716088 13692478 O3M_22875 Escherichia coli O104:H4 str. 2009EL-2050 Prophage integrase YP_006772189.1 4714826 D 1134782 CDS YP_006772190.1 410484644 13692479 4720418..4720762 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 4720762 13692479 O3M_22890 Escherichia coli O104:H4 str. 2009EL-2050 transposase, IS110 family protein YP_006772190.1 4720418 D 1134782 CDS YP_006772191.1 410484645 13692480 complement(4721091..4721339) 1 NC_018650.1 hypothetical protein 4721339 13692480 O3M_22900 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772191.1 4721091 R 1134782 CDS YP_006772192.1 410484646 13692481 4721406..4722167 1 NC_018650.1 hypothetical protein 4722167 13692481 O3M_22905 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772192.1 4721406 D 1134782 CDS YP_006772193.1 410484647 13692482 4722528..4726385 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; Serine protease pet precursor (Plasmid-encoded toxin pet) 4726385 13692482 O3M_22910 Escherichia coli O104:H4 str. 2009EL-2050 Serine protease pet precursor (Plasmid-encoded toxin pet) YP_006772193.1 4722528 D 1134782 CDS YP_006772194.1 410484648 13692483 4726432..4727013 1 NC_018650.1 hypothetical protein 4727013 13692483 O3M_22915 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772194.1 4726432 D 1134782 CDS YP_006772195.1 410484649 13692484 complement(4727205..4728818) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; transposase 4728818 13692484 O3M_22920 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772195.1 4727205 R 1134782 CDS YP_006772196.1 410484650 13692485 complement(4728849..4729199) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 4729199 13692485 O3M_22925 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772196.1 4728849 R 1134782 CDS YP_006772197.1 410484651 13692486 complement(4729196..4729630) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 4729630 13692486 O3M_22930 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772197.1 4729196 R 1134782 CDS YP_006772198.1 410484652 13692487 complement(4729964..4730371) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; protein encoded within IS 4730371 13692487 O3M_22935 Escherichia coli O104:H4 str. 2009EL-2050 protein encoded within IS YP_006772198.1 4729964 R 1134782 CDS YP_006772199.1 410484653 13692488 4730437..4730940 1 NC_018650.1 COG3464 Transposase and inactivated derivatives; transposase 4730940 13692488 O3M_22940 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772199.1 4730437 D 1134782 CDS YP_006772200.1 410484654 13692489 4732169..4732594 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; transposase OrfA from plasmid origin 4732594 13692489 O3M_22950 Escherichia coli O104:H4 str. 2009EL-2050 transposase OrfA from plasmid origin YP_006772200.1 4732169 D 1134782 CDS YP_006772201.1 410484655 13692490 4732591..4732842 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; IS66 transposase 4732842 13692490 O3M_22955 Escherichia coli O104:H4 str. 2009EL-2050 IS66 transposase YP_006772201.1 4732591 D 1134782 CDS YP_006772202.1 410484656 13692491 4732868..4733194 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein 4733194 13692491 O3M_22960 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS629, IS3 family protein YP_006772202.1 4732868 D 1134782 CDS YP_006772203.1 410484657 13692492 4734265..4735788 1 NC_018650.1 COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid 4735788 13692492 O3M_22970 Escherichia coli O104:H4 str. 2009EL-2050 reverse transcriptase-like protein from prophage or plasmid YP_006772203.1 4734265 D 1134782 CDS YP_006772204.1 410484658 13692493 complement(4736753..4738948) 1 NC_018650.1 COG1629 Outer membrane receptor proteins, mostly Fe transport; Ferric aerobactin receptor 4738948 13692493 O3M_22980 Escherichia coli O104:H4 str. 2009EL-2050 Ferric aerobactin receptor YP_006772204.1 4736753 R 1134782 CDS YP_006772205.1 410484659 13692494 complement(4738954..4740291) 1 NC_018650.1 COG3486 Lysine/ornithine N-monooxygenase; L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase) 4740291 13692494 O3M_22985 Escherichia coli O104:H4 str. 2009EL-2050 L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase) YP_006772205.1 4738954 R 1134782 CDS YP_006772206.1 410484660 13692495 complement(4740288..4742030) 1 NC_018650.1 COG4264 Siderophore synthetase component; Aerobactin siderophore biosynthesis protein 4742030 13692495 O3M_22990 Escherichia coli O104:H4 str. 2009EL-2050 Aerobactin siderophore biosynthesis protein YP_006772206.1 4740288 R 1134782 CDS YP_006772207.1 410484661 13692496 complement(4742030..4742977) 1 NC_018650.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; siderophore biosynthesis protein 4742977 13692496 O3M_22995 Escherichia coli O104:H4 str. 2009EL-2050 siderophore biosynthesis protein YP_006772207.1 4742030 R 1134782 CDS YP_006772208.1 410484662 13692497 complement(4742978..4744759) 1 NC_018650.1 COG4264 Siderophore synthetase component; aerobactin siderophore biosynthesis protein 4744759 13692497 O3M_23000 Escherichia coli O104:H4 str. 2009EL-2050 aerobactin siderophore biosynthesis protein YP_006772208.1 4742978 R 1134782 CDS YP_006772209.1 410484663 13692498 4744838..4746031 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; membrane transport protein, major facilitator superfamily 4746031 13692498 O3M_23005 Escherichia coli O104:H4 str. 2009EL-2050 membrane transport protein, major facilitator superfamily YP_006772209.1 4744838 D 1134782 CDS YP_006772210.1 410484664 13692499 4747244..4747411 1 NC_018650.1 hypothetical protein 4747411 13692499 O3M_23010 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772210.1 4747244 D 1134782 CDS YP_006772211.1 410484665 13692500 complement(4747398..4747583) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; transposase 4747583 13692500 O3M_23015 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772211.1 4747398 R 1134782 CDS YP_006772212.1 410484666 13692501 4747647..4748789 1 NC_018650.1 COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 4748789 13692501 O3M_23020 Escherichia coli O104:H4 str. 2009EL-2050 transposase, IS110 family protein YP_006772212.1 4747647 D 1134782 CDS YP_006772213.1 410484667 13692502 complement(4748829..4749719) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORFB, IS629, IS3 family protein 4749719 13692502 O3M_23025 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORFB, IS629, IS3 family protein YP_006772213.1 4748829 R 1134782 CDS YP_006772214.1 410484668 13692503 complement(4749716..4750042) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein 4750042 13692503 O3M_23030 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS629, IS3 family protein YP_006772214.1 4749716 R 1134782 CDS YP_006772215.1 410484669 13692504 complement(4750271..4750555) 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF1, IS66 family protein 4750555 13692504 O3M_23035 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF1, IS66 family protein YP_006772215.1 4750271 R 1134782 CDS YP_006772216.1 410484670 13692505 complement(4750620..4751744) 1 NC_018650.1 COG4584 Transposase and inactivated derivatives; transposase 4751744 13692505 O3M_23040 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772216.1 4750620 R 1134782 CDS YP_006772217.1 410484671 13692506 4751965..4752474 1 NC_018650.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 4752474 13692506 O3M_23045 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772217.1 4751965 D 1134782 CDS YP_006772218.1 410484672 13692507 4752537..4752755 1 NC_018650.1 COG3328 Transposase and inactivated derivatives; transposase 4752755 13692507 O3M_23050 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772218.1 4752537 D 1134782 CDS YP_006772219.1 410484673 13692508 complement(4752906..4757024) 1 NC_018650.1 COG3468 Type V secretory pathway, adhesin AidA; Serine protease pic precursor (ShMu) 4757024 13692508 O3M_23055 Escherichia coli O104:H4 str. 2009EL-2050 Serine protease pic precursor (ShMu) YP_006772219.1 4752906 R 1134782 CDS YP_006772220.1 410484674 13692509 complement(4757189..4757560) 1 NC_018650.1 COG2801 Transposase and inactivated derivatives; IS629 ORF2; transposase 4757560 13692509 O3M_23060 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772220.1 4757189 R 1134782 CDS YP_006772221.1 410484675 13692510 complement(4757752..4758933) 1 NC_018650.1 COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein from prophage or plasmid 4758933 13692510 O3M_23065 Escherichia coli O104:H4 str. 2009EL-2050 reverse transcriptase-like protein from prophage or plasmid YP_006772221.1 4757752 R 1134782 CDS YP_006772222.1 410484676 13692511 complement(4759052..4759276) 1 NC_018650.1 CP4-6 prophage (modular protein); COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein 4759276 13692511 O3M_23070 Escherichia coli O104:H4 str. 2009EL-2050 reverse transcriptase-like protein YP_006772222.1 4759052 R 1134782 CDS YP_006772223.1 410484677 13692512 complement(4760347..4760673) 1 NC_018650.1 COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein 4760673 13692512 O3M_23080 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS629, IS3 family protein YP_006772223.1 4760347 R 1134782 CDS YP_006772224.1 410484678 13692513 4761197..4761670 1 NC_018650.1 antirestriction protein 4761670 13692513 O3M_23085 Escherichia coli O104:H4 str. 2009EL-2050 antirestriction protein YP_006772224.1 4761197 D 1134782 CDS YP_006772225.1 410484679 13692514 4761686..4762162 1 NC_018650.1 COG2003 DNA repair proteins; RADC family DNA repair protein 4762162 13692514 O3M_23090 Escherichia coli O104:H4 str. 2009EL-2050 RADC family DNA repair protein YP_006772225.1 4761686 D 1134782 CDS YP_006772226.1 410484680 13692515 4762249..4762470 1 NC_018650.1 hypothetical protein 4762470 13692515 O3M_23095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772226.1 4762249 D 1134782 CDS YP_006772227.1 410484681 13692516 4762550..4762927 1 NC_018650.1 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 4762927 13692516 O3M_23100 Escherichia coli O104:H4 str. 2009EL-2050 antitoxin of the YeeV-YeeU toxin-antitoxin system YP_006772227.1 4762550 D 1134782 CDS YP_006772228.1 410484682 13692517 4762974..4763351 1 NC_018650.1 hypothetical protein 4763351 13692517 O3M_23105 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772228.1 4762974 D 1134782 CDS YP_006772229.1 410484683 13692518 4763348..4763836 1 NC_018650.1 hypothetical protein 4763836 13692518 O3M_23110 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772229.1 4763348 D 1134782 CDS YP_006772230.1 410484684 13692519 4763856..4764053 1 NC_018650.1 hypothetical protein 4764053 13692519 O3M_23115 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772230.1 4763856 D 1134782 CDS YP_006772231.1 410484685 13692520 4764138..4764980 1 NC_018650.1 hypothetical protein 4764980 13692520 O3M_23120 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772231.1 4764138 D 1134782 CDS YP_006772232.1 410484686 13692521 4765729..4767267 1 NC_018650.1 COG3710 DNA-binding winged-HTH domains; DNA-binding transcriptional activator CadC 4767267 13692521 O3M_23125 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator CadC YP_006772232.1 4765729 D 1134782 CDS YP_006772233.1 410484687 13692522 4767633..4768967 1 NC_018650.1 COG0531 Amino acid transporters; lysine/cadaverine antiporter 4768967 cadB 13692522 cadB Escherichia coli O104:H4 str. 2009EL-2050 lysine/cadaverine antiporter YP_006772233.1 4767633 D 1134782 CDS YP_006772234.1 410484688 13692523 4769047..4771194 1 NC_018650.1 COG1982 Arginine/lysine/ornithine decarboxylases; lysine decarboxylase CadA 4771194 13692523 O3M_23135 Escherichia coli O104:H4 str. 2009EL-2050 lysine decarboxylase CadA YP_006772234.1 4769047 D 1134782 CDS YP_006772235.1 410484689 13692524 4771253..4772710 1 NC_018650.1 COG3104 Dipeptide/tripeptide permease; transporter 4772710 13692524 O3M_23140 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772235.1 4771253 D 1134782 CDS YP_006772236.1 410484690 13692525 4772947..4774464 1 NC_018650.1 COG1190 Lysyl-tRNA synthetase (class II); lysyl-tRNA synthetase 4774464 13692525 O3M_23145 Escherichia coli O104:H4 str. 2009EL-2050 lysyl-tRNA synthetase YP_006772236.1 4772947 D 1134782 CDS YP_006772237.1 410484691 13692526 complement(4774583..4774756) 1 NC_018650.1 hypothetical protein 4774756 13692526 O3M_23150 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772237.1 4774583 R 1134782 CDS YP_006772238.1 410484692 13692527 complement(4774784..4775080) 1 NC_018650.1 hypothetical protein 4775080 13692527 O3M_23155 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772238.1 4774784 R 1134782 CDS YP_006772239.1 410484693 13692528 complement(4775307..4775579) 1 NC_018650.1 COG2388 Predicted acetyltransferase; acyltransferase 4775579 13692528 O3M_23160 Escherichia coli O104:H4 str. 2009EL-2050 acyltransferase YP_006772239.1 4775307 R 1134782 CDS YP_006772240.1 410484694 13692529 complement(4775591..4775821) 1 NC_018650.1 COG3592 Uncharacterized conserved protein; hypothetical protein 4775821 13692529 O3M_23165 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772240.1 4775591 R 1134782 CDS YP_006772241.1 410484695 13692530 4776002..4777633 1 NC_018650.1 COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; sensory histidine kinase DcuS 4777633 13692530 O3M_23170 Escherichia coli O104:H4 str. 2009EL-2050 sensory histidine kinase DcuS YP_006772241.1 4776002 D 1134782 CDS YP_006772242.1 410484696 13692531 4777630..4778349 1 NC_018650.1 COG4565 Response regulator of citrate/malate metabolism; DNA-binding transcriptional activator DcuR 4778349 13692531 O3M_23175 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional activator DcuR YP_006772242.1 4777630 D 1134782 CDS YP_006772243.1 410484697 13692532 4778920..4780260 1 NC_018650.1 COG2704 Anaerobic C4-dicarboxylate transporter; anaerobic C4-dicarboxylate transporter 4780260 13692532 O3M_23180 Escherichia coli O104:H4 str. 2009EL-2050 anaerobic C4-dicarboxylate transporter YP_006772243.1 4778920 D 1134782 CDS YP_006772244.1 410484698 13692533 4780338..4781984 1 NC_018650.1 COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase FumB 4781984 13692533 O3M_23185 Escherichia coli O104:H4 str. 2009EL-2050 fumarate hydratase FumB YP_006772244.1 4780338 D 1134782 CDS YP_006772245.1 410484699 13692534 4782107..4782736 1 NC_018650.1 COG3647 Predicted membrane protein; hypothetical protein 4782736 13692534 O3M_23190 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772245.1 4782107 D 1134782 CDS YP_006772246.1 410484700 13692535 complement(4782875..4784284) 1 NC_018650.1 COG2211 Na+/melibiose symporter and related transporters; melibiose:sodium symporter 4784284 13692535 O3M_23195 Escherichia coli O104:H4 str. 2009EL-2050 melibiose:sodium symporter YP_006772246.1 4782875 R 1134782 CDS YP_006772247.1 410484701 13692536 complement(4784399..4785754) 1 NC_018650.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; alpha-galactosidase 4785754 13692536 O3M_23200 Escherichia coli O104:H4 str. 2009EL-2050 alpha-galactosidase YP_006772247.1 4784399 R 1134782 CDS YP_006772248.1 410484702 13692537 4786037..4786945 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator MelR 4786945 13692537 O3M_23205 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator MelR YP_006772248.1 4786037 D 1134782 CDS YP_006772249.1 410484703 13692538 4787141..4789411 1 NC_018650.1 COG1982 Arginine/lysine/ornithine decarboxylases; arginine decarboxylase 4789411 13692538 O3M_23210 Escherichia coli O104:H4 str. 2009EL-2050 arginine decarboxylase YP_006772249.1 4787141 D 1134782 CDS YP_006772250.1 410484704 13692539 4789736..4790497 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 4790497 13692539 O3M_23215 Escherichia coli O104:H4 str. 2009EL-2050 AraC family transcriptional regulator YP_006772250.1 4789736 D 1134782 CDS YP_006772251.1 410484705 13692540 4790634..4791971 1 NC_018650.1 COG0531 Amino acid transporters; arginine:agmatin antiporter 4791971 13692540 O3M_23220 Escherichia coli O104:H4 str. 2009EL-2050 arginine:agmatin antiporter YP_006772251.1 4790634 D 1134782 CDS YP_006772252.1 410484706 13692541 4792075..4793718 1 NC_018650.1 COG2194 Predicted membrane-associated, metal-dependent hydrolase; metal dependent hydrolase 4793718 13692541 O3M_23225 Escherichia coli O104:H4 str. 2009EL-2050 metal dependent hydrolase YP_006772252.1 4792075 D 1134782 CDS YP_006772253.1 410484707 13692542 4793715..4794383 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator BasR 4794383 13692542 O3M_23230 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator BasR YP_006772253.1 4793715 D 1134782 CDS YP_006772254.1 410484708 13692543 4794393..4795484 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor protein BasS/PmrB 4795484 13692543 O3M_23235 Escherichia coli O104:H4 str. 2009EL-2050 sensor protein BasS/PmrB YP_006772254.1 4794393 D 1134782 CDS YP_006772255.1 410484709 13692544 complement(4795661..4797163) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; proline/glycine betaine transporter 4797163 13692544 O3M_23240 Escherichia coli O104:H4 str. 2009EL-2050 proline/glycine betaine transporter YP_006772255.1 4795661 R 1134782 CDS YP_006772256.1 410484710 13692545 complement(4797427..4798305) 1 NC_018650.1 hypothetical protein 4798305 13692545 O3M_23245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772256.1 4797427 R 1134782 CDS YP_006772257.1 410484711 13692546 complement(4798302..4800530) 1 NC_018650.1 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 4800530 13692546 O3M_23250 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772257.1 4798302 R 1134782 CDS YP_006772258.1 410484712 13692547 4800932..4801267 1 NC_018650.1 COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; alkylphosphonate uptake protein in phosphonate metabolism 4801267 13692547 O3M_23255 Escherichia coli O104:H4 str. 2009EL-2050 alkylphosphonate uptake protein in phosphonate metabolism YP_006772258.1 4800932 D 1134782 CDS YP_006772259.1 410484713 13692548 4801427..4801870 1 NC_018650.1 COG2764 Uncharacterized protein conserved in bacteria; hypothetical protein 4801870 13692548 O3M_23260 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772259.1 4801427 D 1134782 CDS YP_006772260.1 410484714 13692549 4802003..4802791 1 NC_018650.1 COG3638 ABC-type phosphate/phosphonate transport system, ATPase component; phosphonate/organophosphate ester transporter subunit 4802791 13692549 O3M_23265 Escherichia coli O104:H4 str. 2009EL-2050 phosphonate/organophosphate ester transporter subunit YP_006772260.1 4802003 D 1134782 CDS YP_006772261.1 410484715 13692550 4802816..4803832 1 NC_018650.1 COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component; phosphonate/organophosphate ester transporter subunit PhnD 4803832 13692550 O3M_23270 Escherichia coli O104:H4 str. 2009EL-2050 phosphonate/organophosphate ester transporter subunit PhnD YP_006772261.1 4802816 D 1134782 CDS YP_006772262.1 410484716 13692551 4803938..4804717 1 NC_018650.1 COG3639 ABC-type phosphate/phosphonate transport system, permease component; Pn transporter membrane channel protein 4804717 13692551 O3M_23275 Escherichia coli O104:H4 str. 2009EL-2050 Pn transporter membrane channel protein YP_006772262.1 4803938 D 1134782 CDS YP_006772263.1 410484717 13692552 4804738..4805463 1 NC_018650.1 COG2188 Transcriptional regulators; phosphonate metabolism transcriptional regulator PhnF 4805463 13692552 O3M_23280 Escherichia coli O104:H4 str. 2009EL-2050 phosphonate metabolism transcriptional regulator PhnF YP_006772263.1 4804738 D 1134782 CDS YP_006772264.1 410484718 13692553 4805464..4805916 1 NC_018650.1 COG3624 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4805916 13692553 O3M_23285 Escherichia coli O104:H4 str. 2009EL-2050 carbon-phosphorus lyase complex subunit YP_006772264.1 4805464 D 1134782 CDS YP_006772265.1 410484719 13692554 4805913..4806497 1 NC_018650.1 COG3625 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4806497 phnH 13692554 phnH Escherichia coli O104:H4 str. 2009EL-2050 carbon-phosphorus lyase complex subunit YP_006772265.1 4805913 D 1134782 CDS YP_006772266.1 410484720 13692555 4806497..4807561 1 NC_018650.1 COG3626 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit 4807561 13692555 O3M_23295 Escherichia coli O104:H4 str. 2009EL-2050 carbon-phosphorus lyase complex subunit YP_006772266.1 4806497 D 1134782 CDS YP_006772267.1 410484721 13692637 4807554..4808399 1 NC_018650.1 COG3627 Uncharacterized enzyme of phosphonate metabolism; carbon-phosphorus lyase complex subunit PhnJ 4808399 13692637 O3M_23300 Escherichia coli O104:H4 str. 2009EL-2050 carbon-phosphorus lyase complex subunit PhnJ YP_006772267.1 4807554 D 1134782 CDS YP_006772268.1 410484722 13692638 4808396..4809154 1 NC_018650.1 COG4107 ABC-type phosphonate transport system, ATPase component; phosphonate C-P lyase system protein PhnK 4809154 phnK 13692638 phnK Escherichia coli O104:H4 str. 2009EL-2050 phosphonate C-P lyase system protein PhnK YP_006772268.1 4808396 D 1134782 CDS YP_006772269.1 410484723 13692639 4809331..4810011 1 NC_018650.1 COG4778 ABC-type phosphonate transport system, ATPase component; carbon-phosphorus lyase complex subunit PhnL 4810011 13692639 O3M_23310 Escherichia coli O104:H4 str. 2009EL-2050 carbon-phosphorus lyase complex subunit PhnL YP_006772269.1 4809331 D 1134782 CDS YP_006772270.1 410484724 13692640 4810008..4811144 1 NC_018650.1 COG3454 Metal-dependent hydrolase involved in phosphonate metabolism; phosphonate metabolism protein PhnM 4811144 13692640 O3M_23315 Escherichia coli O104:H4 str. 2009EL-2050 phosphonate metabolism protein PhnM YP_006772270.1 4810008 D 1134782 CDS YP_006772271.1 410484725 13692641 4811144..4811701 1 NC_018650.1 COG3709 Uncharacterized component of phosphonate metabolism; ribose 1,5-bisphosphokinase 4811701 13692641 O3M_23320 Escherichia coli O104:H4 str. 2009EL-2050 ribose 1,5-bisphosphokinase YP_006772271.1 4811144 D 1134782 CDS YP_006772272.1 410484726 13692642 4811688..4812122 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; aminoalkylphosphonic acid N-acetyltransferase 4812122 13692642 O3M_23325 Escherichia coli O104:H4 str. 2009EL-2050 aminoalkylphosphonic acid N-acetyltransferase YP_006772272.1 4811688 D 1134782 CDS YP_006772273.1 410484727 13692643 4812124..4812882 1 NC_018650.1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; carbon-phosphorus lyase complex accessory protein 4812882 phnP 13692643 phnP Escherichia coli O104:H4 str. 2009EL-2050 carbon-phosphorus lyase complex accessory protein YP_006772273.1 4812124 D 1134782 CDS YP_006772274.1 410484728 13692644 complement(4813029..4813358) 1 NC_018650.1 hypothetical protein 4813358 13692644 O3M_23335 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772274.1 4813029 R 1134782 CDS YP_006772275.1 410484729 13692645 complement(4813427..4813744) 1 NC_018650.1 COG0698 Ribose 5-phosphate isomerase RpiB; hypothetical protein 4813744 13692645 O3M_23340 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772275.1 4813427 R 1134782 CDS YP_006772276.1 410484730 13692646 4813997..4815982 1 NC_018650.1 COG2015 Alkyl sulfatase and related hydrolases; hypothetical protein 4815982 13692646 O3M_23345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772276.1 4813997 D 1134782 CDS YP_006772277.1 410484731 13692647 4816191..4816466 1 NC_018650.1 formate dehydrogenase H 4816466 13692647 O3M_23350 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase H YP_006772277.1 4816191 D 1134782 CDS YP_006772278.1 410484732 13692648 4816485..4817516 1 NC_018650.1 COG1566 Multidrug resistance efflux pump; multidrug resistance protein MdtN 4817516 13692648 O3M_23355 Escherichia coli O104:H4 str. 2009EL-2050 multidrug resistance protein MdtN YP_006772278.1 4816485 D 1134782 CDS YP_006772279.1 410484733 13692649 4817516..4819567 1 NC_018650.1 COG1289 Predicted membrane protein; multidrug efflux system protein MdtO 4819567 13692649 O3M_23360 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein MdtO YP_006772279.1 4817516 D 1134782 CDS YP_006772280.1 410484734 13692650 4819564..4821030 1 NC_018650.1 COG1538 Outer membrane protein; outer membrane efflux protein MdtP 4821030 13692650 O3M_23365 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane efflux protein MdtP YP_006772280.1 4819564 D 1134782 CDS YP_006772281.1 410484735 13692651 4821228..4821647 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-H, selenopolypeptide subunit 4821647 13692651 O3M_23370 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-H, selenopolypeptide subunit YP_006772281.1 4821228 D 1134782 CDS YP_006772282.1 410484736 13692652 4821696..4823375 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-H, selenopolypeptide subunit 4823375 13692652 O3M_23375 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-H, selenopolypeptide subunit YP_006772282.1 4821696 D 1134782 CDS YP_006772283.1 410484737 13692653 4823469..4824158 1 NC_018650.1 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 4824158 13692653 O3M_23380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772283.1 4823469 D 1134782 CDS YP_006772284.1 410484738 13692654 complement(4824236..4825549) 1 NC_018650.1 COG1301 Na+/H+-dicarboxylate symporters; glutamate/aspartate:proton symporter 4825549 gltP 13692654 gltP Escherichia coli O104:H4 str. 2009EL-2050 glutamate/aspartate:proton symporter YP_006772284.1 4824236 R 1134782 CDS YP_006772285.1 410484739 13692655 complement(4825891..4826487) 1 NC_018650.1 COG4235 Cytochrome c biogenesis factor; formate-dependent nitrite reductase complex subunit NrfG 4826487 13692655 O3M_23390 Escherichia coli O104:H4 str. 2009EL-2050 formate-dependent nitrite reductase complex subunit NrfG YP_006772285.1 4825891 R 1134782 CDS YP_006772286.1 410484740 13692656 complement(4826484..4826867) 1 NC_018650.1 COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; formate-dependent nitrite reductase complex subunit NrfF 4826867 13692656 O3M_23395 Escherichia coli O104:H4 str. 2009EL-2050 formate-dependent nitrite reductase complex subunit NrfF YP_006772286.1 4826484 R 1134782 CDS YP_006772287.1 410484741 13692657 complement(4826860..4828518) 1 NC_018650.1 COG1138 Cytochrome c biogenesis factor; heme lyase subunit NrfE 4828518 13692657 O3M_23400 Escherichia coli O104:H4 str. 2009EL-2050 heme lyase subunit NrfE YP_006772287.1 4826860 R 1134782 CDS YP_006772288.1 410484742 13692658 complement(4828598..4829554) 1 NC_018650.1 COG3301 Formate-dependent nitrite reductase, membrane component; formate-dependent nitrite reductase, membrane subunit 4829554 13692658 O3M_23405 Escherichia coli O104:H4 str. 2009EL-2050 formate-dependent nitrite reductase, membrane subunit YP_006772288.1 4828598 R 1134782 CDS YP_006772289.1 410484743 13692659 complement(4829551..4830222) 1 NC_018650.1 Fe-S center; COG0437 Fe-S-cluster-containing hydrogenase components 1; formate-dependent nitrite reductase 4830222 13692659 O3M_23410 Escherichia coli O104:H4 str. 2009EL-2050 formate-dependent nitrite reductase YP_006772289.1 4829551 R 1134782 CDS YP_006772290.1 410484744 13692660 complement(4830219..4830785) 1 NC_018650.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; cytochrome c nitrite reductase pentaheme subunit 4830785 13692660 O3M_23415 Escherichia coli O104:H4 str. 2009EL-2050 cytochrome c nitrite reductase pentaheme subunit YP_006772290.1 4830219 R 1134782 CDS YP_006772291.1 410484745 13692661 complement(4830830..4832266) 1 NC_018650.1 COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit; cytochrome c nitrite reductase subunit c552 4832266 nrfA 13692661 nrfA Escherichia coli O104:H4 str. 2009EL-2050 cytochrome c nitrite reductase subunit c552 YP_006772291.1 4830830 R 1134782 CDS YP_006772292.1 410484746 13692662 4832658..4834616 1 NC_018650.1 COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; acetyl-CoA synthetase 4834616 13692662 O3M_23425 Escherichia coli O104:H4 str. 2009EL-2050 acetyl-CoA synthetase YP_006772292.1 4832658 D 1134782 CDS YP_006772293.1 410484747 13692663 4834816..4835130 1 NC_018650.1 COG3162 Predicted membrane protein; hypothetical protein 4835130 13692663 O3M_23430 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772293.1 4834816 D 1134782 CDS YP_006772294.1 410484748 13692664 4835127..4836776 1 NC_018650.1 COG4147 Predicted symporter; acetate permease 4836776 actP 13692664 actP Escherichia coli O104:H4 str. 2009EL-2050 acetate permease YP_006772294.1 4835127 D 1134782 CDS YP_006772295.1 410484749 13692665 4836954..4838246 1 NC_018650.1 COG1357 Uncharacterized low-complexity proteins; hypothetical protein 4838246 13692665 O3M_23440 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772295.1 4836954 D 1134782 CDS YP_006772296.1 410484750 13692666 complement(4838400..4840049) 1 NC_018650.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; cation/proton antiporter 4840049 13692666 O3M_23445 Escherichia coli O104:H4 str. 2009EL-2050 cation/proton antiporter YP_006772296.1 4838400 R 1134782 CDS YP_006772297.1 410484751 13692667 complement(4840200..4841549) 1 NC_018650.1 COG2252 Permeases; permease 4841549 13692667 O3M_23450 Escherichia coli O104:H4 str. 2009EL-2050 permease YP_006772297.1 4840200 R 1134782 CDS YP_006772298.1 410484752 13692668 complement(4842095..4842559) 1 NC_018650.1 COG0789 Predicted transcriptional regulators; redox-sensitivie transcriptional activator Soxr 4842559 13692668 O3M_23455 Escherichia coli O104:H4 str. 2009EL-2050 redox-sensitivie transcriptional activator Soxr YP_006772298.1 4842095 R 1134782 CDS YP_006772299.1 410484753 13692669 4842645..4842968 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator SoxS 4842968 13692669 O3M_23460 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator SoxS YP_006772299.1 4842645 D 1134782 CDS YP_006772300.1 410484754 13692670 complement(4842971..4844557) 1 NC_018650.1 COG4943 Predicted signal transduction protein containing sensor and EAL domains; signal transduction protein (EAL domain containing protein) 4844557 13692670 O3M_23465 Escherichia coli O104:H4 str. 2009EL-2050 signal transduction protein (EAL domain containing protein) YP_006772300.1 4842971 R 1134782 CDS YP_006772301.1 410484755 13692671 4844987..4845268 1 NC_018650.1 hypothetical protein 4845268 13692671 O3M_23470 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772301.1 4844987 D 1134782 CDS YP_006772302.1 410484756 13692672 complement(4845367..4845903) 1 NC_018650.1 COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein 4845903 13692672 O3M_23475 Escherichia coli O104:H4 str. 2009EL-2050 single-stranded DNA-binding protein YP_006772302.1 4845367 R 1134782 CDS YP_006772303.1 410484757 13692673 4846157..4848979 1 NC_018650.1 COG0178 Excinuclease ATPase subunit; excinuclease ABC subunit A 4848979 uvrA 13692673 uvrA Escherichia coli O104:H4 str. 2009EL-2050 excinuclease ABC subunit A YP_006772303.1 4846157 D 1134782 CDS YP_006772304.1 410484758 13692674 complement(4849014..4849370) 1 NC_018650.1 COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein 4849370 13692674 O3M_23485 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772304.1 4849014 R 1134782 CDS YP_006772305.1 410484759 13692675 complement(4849374..4849790) 1 NC_018650.1 COG0432 Uncharacterized conserved protein; hypothetical protein 4849790 13692675 O3M_23490 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772305.1 4849374 R 1134782 CDS YP_006772306.1 410484760 13692676 complement(4849901..4850614) 1 NC_018650.1 COG3700 Acid phosphatase (class B); acid phosphatase/phosphotransferase 4850614 aphA 13692676 aphA Escherichia coli O104:H4 str. 2009EL-2050 acid phosphatase/phosphotransferase YP_006772306.1 4849901 R 1134782 CDS YP_006772307.1 410484761 13692677 4851016..4851519 1 NC_018650.1 hypothetical protein 4851519 13692677 O3M_23500 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772307.1 4851016 D 1134782 CDS YP_006772308.1 410484762 13692678 complement(4851741..4852934) 1 NC_018650.1 COG1448 Aspartate/tyrosine/aromatic aminotransferase; aromatic amino acid aminotransferase 4852934 13692678 O3M_23505 Escherichia coli O104:H4 str. 2009EL-2050 aromatic amino acid aminotransferase YP_006772308.1 4851741 R 1134782 CDS YP_006772309.1 410484763 13692679 complement(4853187..4854266) 1 NC_018650.1 COG0787 Alanine racemase; alanine racemase 4854266 alr 13692679 alr Escherichia coli O104:H4 str. 2009EL-2050 alanine racemase YP_006772309.1 4853187 R 1134782 CDS YP_006772310.1 410484764 13692680 complement(4854319..4855734) 1 NC_018650.1 COG0305 Replicative DNA helicase; replicative DNA helicase 4855734 13692680 O3M_23515 Escherichia coli O104:H4 str. 2009EL-2050 replicative DNA helicase YP_006772310.1 4854319 R 1134782 CDS YP_006772311.1 410484765 13692681 4855817..4856800 1 NC_018650.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; quinone oxidoreductase 4856800 13692681 O3M_23520 Escherichia coli O104:H4 str. 2009EL-2050 quinone oxidoreductase YP_006772311.1 4855817 D 1134782 CDS YP_006772312.1 410484766 13692682 complement(4856966..4857208) 1 NC_018650.1 phage shock protein G 4857208 pspG 13692682 pspG Escherichia coli O104:H4 str. 2009EL-2050 phage shock protein G YP_006772312.1 4856966 R 1134782 CDS YP_006772313.1 410484767 13692683 complement(4857342..4858361) 1 NC_018650.1 COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase A 4858361 13692683 O3M_23530 Escherichia coli O104:H4 str. 2009EL-2050 tRNA-dihydrouridine synthase A YP_006772313.1 4857342 R 1134782 CDS YP_006772314.1 410484768 13692684 complement(4858743..4859456) 1 NC_018650.1 hypothetical protein 4859456 13692684 O3M_23535 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772314.1 4858743 R 1134782 CDS YP_006772315.1 410484769 13692685 complement(4859480..4859734) 1 NC_018650.1 hypothetical protein 4859734 13692685 O3M_23540 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772315.1 4859480 R 1134782 CDS YP_006772316.1 410484770 13692686 4860052..4860567 1 NC_018650.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; zinc uptake transcriptional repressor 4860567 13692686 O3M_23545 Escherichia coli O104:H4 str. 2009EL-2050 zinc uptake transcriptional repressor YP_006772316.1 4860052 D 1134782 CDS YP_006772317.1 410484771 13692687 complement(4860609..4860818) 1 NC_018650.1 COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein 4860818 13692687 O3M_23550 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772317.1 4860609 R 1134782 CDS YP_006772318.1 410484772 13692688 complement(4860914..4862260) 1 NC_018650.1 COG0534 Na+-driven multidrug efflux pump; DNA-damage-inducible SOS response protein 4862260 13692688 O3M_23555 Escherichia coli O104:H4 str. 2009EL-2050 DNA-damage-inducible SOS response protein YP_006772318.1 4860914 R 1134782 CDS YP_006772319.1 410484773 13692689 complement(4862333..4862941) 1 NC_018650.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); LexA repressor 4862941 13692689 O3M_23560 Escherichia coli O104:H4 str. 2009EL-2050 LexA repressor YP_006772319.1 4862333 R 1134782 CDS YP_006772320.1 410484774 13692690 complement(4863051..4863419) 1 NC_018650.1 COG0818 Diacylglycerol kinase; diacylglycerol kinase 4863419 13692690 O3M_23565 Escherichia coli O104:H4 str. 2009EL-2050 diacylglycerol kinase YP_006772320.1 4863051 R 1134782 CDS YP_006772321.1 410484775 13692691 4863590..4866013 1 NC_018650.1 COG2937 Glycerol-3-phosphate O-acyltransferase; glycerol-3-phosphate acyltransferase 4866013 13692691 O3M_23570 Escherichia coli O104:H4 str. 2009EL-2050 glycerol-3-phosphate acyltransferase YP_006772321.1 4863590 D 1134782 CDS YP_006772322.1 410484776 13692692 complement(4866168..4867040) 1 NC_018650.1 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; 4-hydroxybenzoate octaprenyltransferase 4867040 ubiA 13692692 ubiA Escherichia coli O104:H4 str. 2009EL-2050 4-hydroxybenzoate octaprenyltransferase YP_006772322.1 4866168 R 1134782 CDS YP_006772323.1 410484777 13692693 complement(4867053..4867550) 1 NC_018650.1 COG3161 4-hydroxybenzoate synthetase (chorismate lyase); chorismate pyruvate lyase 4867550 ubiC 13692693 ubiC Escherichia coli O104:H4 str. 2009EL-2050 chorismate pyruvate lyase YP_006772323.1 4867053 R 1134782 CDS YP_006772324.1 410484778 13692694 complement(4867773..4869101) 1 NC_018650.1 COG1357 Uncharacterized low-complexity proteins; hypothetical protein 4869101 13692694 O3M_23585 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772324.1 4867773 R 1134782 CDS YP_006772325.1 410484779 13692695 complement(4869159..4869353) 1 NC_018650.1 hypothetical protein 4869353 13692695 O3M_23590 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772325.1 4869159 R 1134782 CDS YP_006772326.1 410484780 13692696 complement(4869582..4870502) 1 NC_018650.1 maltose regulon periplasmic protein 4870502 13692696 O3M_23595 Escherichia coli O104:H4 str. 2009EL-2050 maltose regulon periplasmic protein YP_006772326.1 4869582 R 1134782 CDS YP_006772327.1 410484781 13692697 complement(4870654..4871994) 1 NC_018650.1 COG4580 Maltoporin (phage lambda and maltose receptor); maltoporin 4871994 lamB 13692697 lamB Escherichia coli O104:H4 str. 2009EL-2050 maltoporin YP_006772327.1 4870654 R 1134782 CDS YP_006772328.1 410484782 13692698 complement(4872066..4873181) 1 NC_018650.1 COG3839 ABC-type sugar transport systems, ATPase components; maltose/maltodextrin transporter ATP-binding protein 4873181 13692698 O3M_23605 Escherichia coli O104:H4 str. 2009EL-2050 maltose/maltodextrin transporter ATP-binding protein YP_006772328.1 4872066 R 1134782 CDS YP_006772329.1 410484783 13692699 4873358..4873453 1 NC_018650.1 hypothetical protein 4873453 13692699 O3M_23610 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772329.1 4873358 D 1134782 CDS YP_006772330.1 410484784 13692700 4873546..4874736 1 NC_018650.1 COG2182 Maltose-binding periplasmic proteins/domains; maltose ABC transporter substrate-binding protein 4874736 malE 13692700 malE Escherichia coli O104:H4 str. 2009EL-2050 maltose ABC transporter substrate-binding protein YP_006772330.1 4873546 D 1134782 CDS YP_006772331.1 410484785 13692701 4874890..4876434 1 NC_018650.1 COG1175 ABC-type sugar transport systems, permease components; maltose transporter membrane protein 4876434 malF 13692701 malF Escherichia coli O104:H4 str. 2009EL-2050 maltose transporter membrane protein YP_006772331.1 4874890 D 1134782 CDS YP_006772332.1 410484786 13692702 4876449..4877339 1 NC_018650.1 COG3833 ABC-type maltose transport systems, permease component; maltose transporter permease 4877339 malG 13692702 malG Escherichia coli O104:H4 str. 2009EL-2050 maltose transporter permease YP_006772332.1 4876449 D 1134782 CDS YP_006772333.1 410484787 13692703 4877711..4879186 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; D-xylose transporter XylE 4879186 xylE 13692703 xylE Escherichia coli O104:H4 str. 2009EL-2050 D-xylose transporter XylE YP_006772333.1 4877711 D 1134782 CDS YP_006772334.1 410484788 13692704 complement(4879230..4879640) 1 NC_018650.1 COG3223 Predicted membrane protein; phosphate-starvation-inducible protein PsiE 4879640 13692704 O3M_23635 Escherichia coli O104:H4 str. 2009EL-2050 phosphate-starvation-inducible protein PsiE YP_006772334.1 4879230 R 1134782 CDS YP_006772335.1 410484789 13692705 complement(4879766..4879909) 1 NC_018650.1 hypothetical protein 4879909 13692705 O3M_23640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772335.1 4879766 R 1134782 CDS YP_006772336.1 410484790 13692706 complement(4880235..4882331) 1 NC_018650.1 porin 4882331 13692706 O3M_23645 Escherichia coli O104:H4 str. 2009EL-2050 porin YP_006772336.1 4880235 R 1134782 CDS YP_006772337.1 410484791 13692707 complement(4882331..4883068) 1 NC_018650.1 hypothetical protein 4883068 13692707 O3M_23650 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772337.1 4882331 R 1134782 CDS YP_006772338.1 410484792 13692708 complement(4883065..4883703) 1 NC_018650.1 hypothetical protein 4883703 13692708 O3M_23655 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772338.1 4883065 R 1134782 CDS YP_006772339.1 410484793 13692709 complement(4884414..4886063) 1 NC_018650.1 COG0166 Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase 4886063 pgi 13692709 pgi Escherichia coli O104:H4 str. 2009EL-2050 glucose-6-phosphate isomerase YP_006772339.1 4884414 R 1134782 CDS YP_006772340.1 410484794 13692710 4886588..4887937 1 NC_018650.1 COG0527 Aspartokinases; aspartate kinase III 4887937 13692710 O3M_23665 Escherichia coli O104:H4 str. 2009EL-2050 aspartate kinase III YP_006772340.1 4886588 D 1134782 CDS YP_006772341.1 410484795 13692711 4888082..4889008 1 NC_018650.1 COG0464 ATPases of the AAA+ class; hypothetical protein 4889008 13692711 O3M_23670 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772341.1 4888082 D 1134782 CDS YP_006772342.1 410484796 13692712 complement(4889044..4889808) 1 NC_018650.1 COG3541 Predicted nucleotidyltransferase; hypothetical protein 4889808 13692712 O3M_23675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772342.1 4889044 R 1134782 CDS YP_006772343.1 410484797 13692713 complement(4889841..4890968) 1 NC_018650.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 4890968 13692713 O3M_23680 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772343.1 4889841 R 1134782 CDS YP_006772344.1 410484798 13692714 4891497..4891769 1 NC_018650.1 hypothetical protein 4891769 13692714 O3M_23685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772344.1 4891497 D 1134782 CDS YP_006772345.1 410484799 13692715 complement(4891770..4892642) 1 NC_018650.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 23S rRNA pseudouridine synthase F 4892642 13692715 O3M_23690 Escherichia coli O104:H4 str. 2009EL-2050 23S rRNA pseudouridine synthase F YP_006772345.1 4891770 R 1134782 CDS YP_006772346.1 410484800 13692716 4892854..4893543 1 NC_018650.1 COG3340 Peptidase E; (alpha)-aspartyl dipeptidase 4893543 13692716 O3M_23695 Escherichia coli O104:H4 str. 2009EL-2050 (alpha)-aspartyl dipeptidase YP_006772346.1 4892854 D 1134782 CDS YP_006772347.1 410484801 13692717 complement(4893634..4895265) 1 NC_018650.1 COG1283 Na+/phosphate symporter; transporter 4895265 13692717 O3M_23700 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772347.1 4893634 R 1134782 CDS YP_006772348.1 410484802 13692718 complement(4895485..4899168) 1 NC_018650.1 COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain; B12-dependent methionine synthase 4899168 metH 13692718 metH Escherichia coli O104:H4 str. 2009EL-2050 B12-dependent methionine synthase YP_006772348.1 4895485 R 1134782 CDS YP_006772349.1 410484803 13692719 4899368..4900192 1 NC_018650.1 COG1414 Transcriptional regulator; IclR family transcriptional regulator 4900192 13692719 O3M_23710 Escherichia coli O104:H4 str. 2009EL-2050 IclR family transcriptional regulator YP_006772349.1 4899368 D 1134782 CDS YP_006772350.1 410484804 13692720 4900509..4902083 1 NC_018650.1 ShET2 enterotoxin domain-containing protein 4902083 13692720 O3M_23715 Escherichia coli O104:H4 str. 2009EL-2050 ShET2 enterotoxin domain-containing protein YP_006772350.1 4900509 D 1134782 CDS YP_006772351.1 410484805 13692721 complement(4902052..4903788) 1 NC_018650.1 COG4579 Isocitrate dehydrogenase kinase/phosphatase; bifunctional isocitrate dehydrogenase kinase/phosphatase 4903788 aceK 13692721 aceK Escherichia coli O104:H4 str. 2009EL-2050 bifunctional isocitrate dehydrogenase kinase/phosphatase YP_006772351.1 4902052 R 1134782 CDS YP_006772352.1 410484806 13692722 complement(4904069..4905373) 1 NC_018650.1 COG2224 Isocitrate lyase; isocitrate lyase 4905373 13692722 O3M_23725 Escherichia coli O104:H4 str. 2009EL-2050 isocitrate lyase YP_006772352.1 4904069 R 1134782 CDS YP_006772353.1 410484807 13692723 complement(4905403..4907004) 1 NC_018650.1 COG2225 Malate synthase; malate synthase 4907004 13692723 O3M_23730 Escherichia coli O104:H4 str. 2009EL-2050 malate synthase YP_006772353.1 4905403 R 1134782 CDS YP_006772354.1 410484808 13692724 complement(4907273..4908202) 1 NC_018650.1 COG1897 Homoserine trans-succinylase; homoserine O-succinyltransferase 4908202 13692724 O3M_23735 Escherichia coli O104:H4 str. 2009EL-2050 homoserine O-succinyltransferase YP_006772354.1 4907273 R 1134782 CDS YP_006772355.1 410484809 13692725 4908359..4908802 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 4908802 13692725 O3M_23740 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006772355.1 4908359 D 1134782 CDS YP_006772356.1 410484810 13692730 4914553..4916142 1 NC_018650.1 COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4916142 purH 13692730 purH Escherichia coli O104:H4 str. 2009EL-2050 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_006772356.1 4914553 D 1134782 CDS YP_006772357.1 410484811 13692731 4916154..4917443 1 NC_018650.1 COG0151 Phosphoribosylamine-glycine ligase; phosphoribosylamine--glycine ligase 4917443 13692731 O3M_23750 Escherichia coli O104:H4 str. 2009EL-2050 phosphoribosylamine--glycine ligase YP_006772357.1 4916154 D 1134782 CDS YP_006772358.1 410484812 13692732 complement(4917440..4918765) 1 NC_018650.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; transcriptional regulatory protein ZraR 4918765 13692732 O3M_23755 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulatory protein ZraR YP_006772358.1 4917440 R 1134782 CDS YP_006772359.1 410484813 13692733 complement(4918762..4920138) 1 NC_018650.1 COG0642 Signal transduction histidine kinase; sensor protein ZraS 4920138 13692733 O3M_23760 Escherichia coli O104:H4 str. 2009EL-2050 sensor protein ZraS YP_006772359.1 4918762 R 1134782 CDS YP_006772360.1 410484814 13692734 4920376..4920801 1 NC_018650.1 COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; zinc resistance protein 4920801 zraP 13692734 zraP Escherichia coli O104:H4 str. 2009EL-2050 zinc resistance protein YP_006772360.1 4920376 D 1134782 CDS YP_006772361.1 410484815 13692735 complement(4920803..4921498) 1 NC_018650.1 hypothetical protein 4921498 13692735 O3M_23770 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772361.1 4920803 R 1134782 CDS YP_006772362.1 410484816 13692736 complement(4921511..4921783) 1 NC_018650.1 COG0776 Bacterial nucleoid DNA-binding protein; transcriptional regulator HU subunit alpha 4921783 13692736 O3M_23775 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator HU subunit alpha YP_006772362.1 4921511 R 1134782 CDS YP_006772363.1 410484817 13692737 complement(4921970..4922560) 1 NC_018650.1 COG3068 Uncharacterized protein conserved in bacteria; hypothetical protein 4922560 13692737 O3M_23780 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772363.1 4921970 R 1134782 CDS YP_006772364.1 410484818 13692738 complement(4922603..4923274) 1 NC_018650.1 COG1515 Deoxyinosine 3'endonuclease (endonuclease V); endonuclease V 4923274 13692738 O3M_23785 Escherichia coli O104:H4 str. 2009EL-2050 endonuclease V YP_006772364.1 4922603 R 1134782 CDS YP_006772365.1 410484819 13692739 complement(4923284..4924348) 1 NC_018650.1 COG0407 Uroporphyrinogen-III decarboxylase; uroporphyrinogen decarboxylase 4924348 hemE 13692739 hemE Escherichia coli O104:H4 str. 2009EL-2050 uroporphyrinogen decarboxylase YP_006772365.1 4923284 R 1134782 CDS YP_006772366.1 410484820 13692740 complement(4924388..4925161) 1 NC_018650.1 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; NADH pyrophosphatase 4925161 nudC 13692740 nudC Escherichia coli O104:H4 str. 2009EL-2050 NADH pyrophosphatase YP_006772366.1 4924388 R 1134782 CDS YP_006772367.1 410484821 13692741 4925256..4925732 1 NC_018650.1 COG3160 Regulator of sigma D; anti-RNA polymerase sigma 70 factor 4925732 13692741 O3M_23800 Escherichia coli O104:H4 str. 2009EL-2050 anti-RNA polymerase sigma 70 factor YP_006772367.1 4925256 D 1134782 CDS YP_006772368.1 410484822 13692742 4925965..4927860 1 NC_018650.1 COG0422 Thiamine biosynthesis protein ThiC; thiamine biosynthesis protein ThiC 4927860 13692742 O3M_23805 Escherichia coli O104:H4 str. 2009EL-2050 thiamine biosynthesis protein ThiC YP_006772368.1 4925965 D 1134782 CDS YP_006772369.1 410484823 13692743 4927860..4928495 1 NC_018650.1 COG0352 Thiamine monophosphate synthase; thiamine-phosphate pyrophosphorylase 4928495 13692743 O3M_23810 Escherichia coli O104:H4 str. 2009EL-2050 thiamine-phosphate pyrophosphorylase YP_006772369.1 4927860 D 1134782 CDS YP_006772370.1 410484824 13692744 4928488..4929243 1 NC_018650.1 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; thiamin biosynthesis protein ThiF 4929243 13692744 O3M_23815 Escherichia coli O104:H4 str. 2009EL-2050 thiamin biosynthesis protein ThiF YP_006772370.1 4928488 D 1134782 CDS YP_006772371.1 410484825 13692745 4929227..4929427 1 NC_018650.1 COG2104 Sulfur transfer protein involved in thiamine biosynthesis; sulfur carrier protein ThiS 4929427 13692745 O3M_23820 Escherichia coli O104:H4 str. 2009EL-2050 sulfur carrier protein ThiS YP_006772371.1 4929227 D 1134782 CDS YP_006772372.1 410484826 13692746 4929429..4930199 1 NC_018650.1 COG2022 Uncharacterized enzyme of thiazole biosynthesis; thiazole synthase 4930199 thiG 13692746 thiG Escherichia coli O104:H4 str. 2009EL-2050 thiazole synthase YP_006772372.1 4929429 D 1134782 CDS YP_006772373.1 410484827 13692747 4930196..4931329 1 NC_018650.1 COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; thiamine biosynthesis protein ThiH 4931329 thiH 13692747 thiH Escherichia coli O104:H4 str. 2009EL-2050 thiamine biosynthesis protein ThiH YP_006772373.1 4930196 D 1134782 CDS YP_006772374.1 410484828 13692748 complement(4931739..4932278) 1 NC_018650.1 stationary phase growth adaptation protein 4932278 13692748 O3M_23835 Escherichia coli O104:H4 str. 2009EL-2050 stationary phase growth adaptation protein YP_006772374.1 4931739 R 1134782 CDS YP_006772375.1 410484829 13692749 complement(4932491..4936714) 1 NC_018650.1 COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' 4936714 13692749 O3M_23840 Escherichia coli O104:H4 str. 2009EL-2050 DNA-directed RNA polymerase subunit beta' YP_006772375.1 4932491 R 1134782 CDS YP_006772376.1 410484830 13692750 complement(4936791..4940819) 1 NC_018650.1 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-directed RNA polymerase subunit beta 4940819 rpoB 13692750 rpoB Escherichia coli O104:H4 str. 2009EL-2050 DNA-directed RNA polymerase subunit beta YP_006772376.1 4936791 R 1134782 CDS YP_006772377.1 410484831 13692751 complement(4941139..4941504) 1 NC_018650.1 COG0222 Ribosomal protein L7/L12; 50S ribosomal protein L7/L12 4941504 rplL 13692751 rplL Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L7/L12 YP_006772377.1 4941139 R 1134782 CDS YP_006772378.1 410484832 13692752 complement(4941571..4942068) 1 NC_018650.1 COG0244 Ribosomal protein L10; 50S ribosomal protein L10 4942068 rplJ 13692752 rplJ Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L10 YP_006772378.1 4941571 R 1134782 CDS YP_006772379.1 410484833 13692753 complement(4942481..4943185) 1 NC_018650.1 COG0081 Ribosomal protein L1; 50S ribosomal protein L1 4943185 rplA 13692753 rplA Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L1 YP_006772379.1 4942481 R 1134782 CDS YP_006772380.1 410484834 13692754 complement(4943189..4943617) 1 NC_018650.1 COG0080 Ribosomal protein L11; 50S ribosomal protein L11 4943617 rplK 13692754 rplK Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L11 YP_006772380.1 4943189 R 1134782 CDS YP_006772381.1 410484835 13692755 complement(4943776..4944321) 1 NC_018650.1 COG0250 Transcription antiterminator; transcription antitermination protein NusG 4944321 nusG 13692755 nusG Escherichia coli O104:H4 str. 2009EL-2050 transcription antitermination protein NusG YP_006772381.1 4943776 R 1134782 CDS YP_006772382.1 410484836 13692756 complement(4944323..4944706) 1 NC_018650.1 COG0690 Preprotein translocase subunit SecE; preprotein translocase subunit SecE 4944706 secE 13692756 secE Escherichia coli O104:H4 str. 2009EL-2050 preprotein translocase subunit SecE YP_006772382.1 4944323 R 1134782 CDS YP_006772383.1 410484837 13692757 complement(4944936..4946120) 1 NC_018650.1 COG0050 GTPases - translation elongation factors; elongation factor Tu 4946120 13692757 O3M_23880 Escherichia coli O104:H4 str. 2009EL-2050 elongation factor Tu YP_006772383.1 4944936 R 1134782 CDS YP_006772384.1 410484838 13692762 4947038..4947988 1 NC_018650.1 COG1072 Panthothenate kinase; pantothenate kinase 4947988 13692762 O3M_23890 Escherichia coli O104:H4 str. 2009EL-2050 pantothenate kinase YP_006772384.1 4947038 D 1134782 CDS YP_006772385.1 410484839 13692763 complement(4948017..4948982) 1 NC_018650.1 COG1654 Biotin operon repressor; bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor 4948982 13692763 O3M_23895 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor YP_006772385.1 4948017 R 1134782 CDS YP_006772386.1 410484840 13692764 complement(4948979..4950007) 1 NC_018650.1 COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylenolpyruvoylglucosamine reductase 4950007 murB 13692764 murB Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylenolpyruvoylglucosamine reductase YP_006772386.1 4948979 R 1134782 CDS YP_006772387.1 410484841 13692769 complement(4955779..4956636) 1 NC_018650.1 COG0796 Glutamate racemase; glutamate racemase 4956636 13692769 O3M_23905 Escherichia coli O104:H4 str. 2009EL-2050 glutamate racemase YP_006772387.1 4955779 R 1134782 CDS YP_006772388.1 410484842 13692770 complement(4956581..4958425) 1 NC_018650.1 COG4206 Outer membrane cobalamin receptor protein; vitamin B12/cobalamin outer membrane transporter 4958425 btuB 13692770 btuB Escherichia coli O104:H4 str. 2009EL-2050 vitamin B12/cobalamin outer membrane transporter YP_006772388.1 4956581 R 1134782 CDS YP_006772389.1 410484843 13692771 4958794..4959894 1 NC_018650.1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; tRNA (uracil-5-)-methyltransferase 4959894 13692771 O3M_23915 Escherichia coli O104:H4 str. 2009EL-2050 tRNA (uracil-5-)-methyltransferase YP_006772389.1 4958794 D 1134782 CDS YP_006772390.1 410484844 13692772 complement(4959934..4960293) 1 NC_018650.1 hypothetical protein 4960293 13692772 O3M_23920 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772390.1 4959934 R 1134782 CDS YP_006772391.1 410484845 13692773 complement(4960293..4960997) 1 NC_018650.1 COG1309 Transcriptional regulator; DNA-binding transcriptional repressor FabR 4960997 13692773 O3M_23925 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional repressor FabR YP_006772391.1 4960293 R 1134782 CDS YP_006772392.1 410484846 13692774 4961274..4962674 1 NC_018650.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; soluble pyridine nucleotide transhydrogenase 4962674 13692774 O3M_23930 Escherichia coli O104:H4 str. 2009EL-2050 soluble pyridine nucleotide transhydrogenase YP_006772392.1 4961274 D 1134782 CDS YP_006772393.1 410484847 13692775 complement(4962657..4963574) 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator OxyR 4963574 13692775 O3M_23935 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator OxyR YP_006772393.1 4962657 R 1134782 CDS YP_006772394.1 410484848 13692776 complement(4963825..4965108) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 4965108 13692776 O3M_23940 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772394.1 4963825 R 1134782 CDS YP_006772395.1 410484849 13692777 complement(4965175..4966389) 1 NC_018650.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; bifunctional D-altronate/D-mannonate dehydratase 4966389 13692777 O3M_23945 Escherichia coli O104:H4 str. 2009EL-2050 bifunctional D-altronate/D-mannonate dehydratase YP_006772395.1 4965175 R 1134782 CDS YP_006772396.1 410484850 13692778 complement(4966887..4968260) 1 NC_018650.1 COG0165 Argininosuccinate lyase; argininosuccinate lyase 4968260 13692778 O3M_23950 Escherichia coli O104:H4 str. 2009EL-2050 argininosuccinate lyase YP_006772396.1 4966887 R 1134782 CDS YP_006772397.1 410484851 13692779 complement(4968321..4969094) 1 NC_018650.1 COG0548 Acetylglutamate kinase; acetylglutamate kinase 4969094 13692779 O3M_23955 Escherichia coli O104:H4 str. 2009EL-2050 acetylglutamate kinase YP_006772397.1 4968321 R 1134782 CDS YP_006772398.1 410484852 13692780 complement(4969105..4970109) 1 NC_018650.1 COG0002 Acetylglutamate semialdehyde dehydrogenase; N-acetyl-gamma-glutamyl-phosphate reductase 4970109 argC 13692780 argC Escherichia coli O104:H4 str. 2009EL-2050 N-acetyl-gamma-glutamyl-phosphate reductase YP_006772398.1 4969105 R 1134782 CDS YP_006772399.1 410484853 13692781 4970263..4971414 1 NC_018650.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase 4971414 13692781 O3M_23965 Escherichia coli O104:H4 str. 2009EL-2050 acetylornithine deacetylase YP_006772399.1 4970263 D 1134782 CDS YP_006772400.1 410484854 13692782 4971766..4974417 1 NC_018650.1 COG2352 Phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase 4974417 13692782 O3M_23970 Escherichia coli O104:H4 str. 2009EL-2050 phosphoenolpyruvate carboxylase YP_006772400.1 4971766 D 1134782 CDS YP_006772401.1 410484855 13692783 4974600..4976333 1 NC_018650.1 COG2194 Predicted membrane-associated, metal-dependent hydrolase; hypothetical protein 4976333 13692783 O3M_23975 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772401.1 4974600 D 1134782 CDS YP_006772402.1 410484856 13692784 4976548..4977399 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; DNA-binding transcriptional regulator 4977399 13692784 O3M_23980 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006772402.1 4976548 D 1134782 CDS YP_006772403.1 410484857 13692785 complement(4977386..4977727) 1 NC_018650.1 COG1445 Phosphotransferase system fructose-specific component IIB; PTS system fructose-like transporter subunit IIB 4977727 13692785 O3M_23985 Escherichia coli O104:H4 str. 2009EL-2050 PTS system fructose-like transporter subunit IIB YP_006772403.1 4977386 R 1134782 CDS YP_006772404.1 410484858 13692786 complement(4977729..4978607) 1 NC_018650.1 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate lyase II activase 4978607 13692786 O3M_23990 Escherichia coli O104:H4 str. 2009EL-2050 pyruvate formate lyase II activase YP_006772404.1 4977729 R 1134782 CDS YP_006772405.1 410484859 13692787 complement(4978573..4980870) 1 NC_018650.1 COG1882 Pyruvate-formate lyase; formate acetyltransferase 2 4980870 pflD 13692787 pflD Escherichia coli O104:H4 str. 2009EL-2050 formate acetyltransferase 2 YP_006772405.1 4978573 R 1134782 CDS YP_006772406.1 410484860 13692788 complement(4980921..4981241) 1 NC_018650.1 COG1445 Phosphotransferase system fructose-specific component IIB; PTS system fructose-like transporter subunit IIB 4981241 13692788 O3M_24000 Escherichia coli O104:H4 str. 2009EL-2050 PTS system fructose-like transporter subunit IIB YP_006772406.1 4980921 R 1134782 CDS YP_006772407.1 410484861 13692789 complement(4981256..4982335) 1 NC_018650.1 COG1299 Phosphotransferase system, fructose-specific IIC component; PTS system fructose-like transporter subunit IIC 4982335 13692789 O3M_24005 Escherichia coli O104:H4 str. 2009EL-2050 PTS system fructose-like transporter subunit IIC YP_006772407.1 4981256 R 1134782 CDS YP_006772408.1 410484862 13692790 4982644..4985145 1 NC_018650.1 enzyme I component ; enzyme IIA component; COG1925 Phosphotransferase system, HPr-related proteins; PTS system transporter Hpr subunit 4985145 13692790 O3M_24010 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter Hpr subunit YP_006772408.1 4982644 D 1134782 CDS YP_006772409.1 410484863 13692791 4985157..4985819 1 NC_018650.1 COG0176 Transaldolase; fructose-6-phosphate aldolase 4985819 13692791 O3M_24015 Escherichia coli O104:H4 str. 2009EL-2050 fructose-6-phosphate aldolase YP_006772409.1 4985157 D 1134782 CDS YP_006772410.1 410484864 13692792 4985830..4986933 1 NC_018650.1 COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase 4986933 gldA 13692792 gldA Escherichia coli O104:H4 str. 2009EL-2050 glycerol dehydrogenase YP_006772410.1 4985830 D 1134782 CDS YP_006772411.1 410484865 13692793 4986965..4987096 1 NC_018650.1 hypothetical protein 4987096 13692793 O3M_24025 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772411.1 4986965 D 1134782 CDS YP_006772412.1 410484866 13692794 4987208..4987825 1 NC_018650.1 COG3738 Uncharacterized protein conserved in bacteria; hypothetical protein 4987825 13692794 O3M_24030 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772412.1 4987208 D 1134782 CDS YP_006772413.1 410484867 13692795 complement(4987852..4988757) 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 4988757 13692795 O3M_24035 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772413.1 4987852 R 1134782 CDS YP_006772414.1 410484868 13692796 complement(4988851..4991031) 1 NC_018650.1 COG0376 Catalase (peroxidase I); catalase/hydroperoxidase HPI(I) 4991031 13692796 O3M_24040 Escherichia coli O104:H4 str. 2009EL-2050 catalase/hydroperoxidase HPI(I) YP_006772414.1 4988851 R 1134782 CDS YP_006772415.1 410484869 13692797 complement(4991360..4992250) 1 NC_018650.1 COG0685 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase 4992250 metF 13692797 metF Escherichia coli O104:H4 str. 2009EL-2050 5,10-methylenetetrahydrofolate reductase YP_006772415.1 4991360 R 1134782 CDS YP_006772416.1 410484870 13692798 4992326..4992460 1 NC_018650.1 hypothetical protein 4992460 13692798 O3M_24050 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772416.1 4992326 D 1134782 CDS YP_006772417.1 410484871 13692799 complement(4992599..4995031) 1 NC_018650.1 COG0527 Aspartokinases; bifunctional aspartate kinase II/homoserine dehydrogenase II 4995031 metL 13692799 metL Escherichia coli O104:H4 str. 2009EL-2050 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_006772417.1 4992599 R 1134782 CDS YP_006772418.1 410484872 13692800 complement(4995034..4996194) 1 NC_018650.1 COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine gamma-synthase 4996194 13692800 O3M_24060 Escherichia coli O104:H4 str. 2009EL-2050 cystathionine gamma-synthase YP_006772418.1 4995034 R 1134782 CDS YP_006772419.1 410484873 13692801 4996471..4996788 1 NC_018650.1 COG3060 Transcriptional regulator of met regulon; transcriptional repressor protein MetJ 4996788 13692801 O3M_24065 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional repressor protein MetJ YP_006772419.1 4996471 D 1134782 CDS YP_006772420.1 410484874 13692802 4997600..4997872 1 NC_018650.1 COG3677 Transposase and inactivated derivatives; hypothetical protein 4997872 13692802 O3M_24080 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772420.1 4997600 D 1134782 CDS YP_006772421.1 410484875 13692803 4997899..4998084 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; transposase 4998084 13692803 O3M_24085 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772421.1 4997899 D 1134782 CDS YP_006772422.1 410484876 13692804 4998078..4998392 1 NC_018650.1 COG1662 Transposase and inactivated derivatives, IS1 family; iso-IS1 InsB protein, transposase 4998392 13692804 O3M_24090 Escherichia coli O104:H4 str. 2009EL-2050 iso-IS1 InsB protein, transposase YP_006772422.1 4998078 D 1134782 CDS YP_006772423.1 410484877 13692805 complement(4998448..4998684) 1 NC_018650.1 hypothetical protein 4998684 13692805 O3M_24095 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772423.1 4998448 R 1134782 CDS YP_006772424.1 410484878 13692806 complement(4998686..5002870) 1 NC_018650.1 COG3209 Rhs family protein; rhsB element core protein RshB 5002870 13692806 O3M_24100 Escherichia coli O104:H4 str. 2009EL-2050 rhsB element core protein RshB YP_006772424.1 4998686 R 1134782 CDS YP_006772425.1 410484879 13692807 complement(5003030..5003242) 1 NC_018650.1 COG0254 Ribosomal protein L31; 50S ribosomal protein L31 5003242 rpmE 13692807 rpmE Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L31 YP_006772425.1 5003030 R 1134782 CDS YP_006772426.1 410484880 13692808 5003445..5005643 1 NC_018650.1 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; primosome assembly protein PriA 5005643 13692808 O3M_24110 Escherichia coli O104:H4 str. 2009EL-2050 primosome assembly protein PriA YP_006772426.1 5003445 D 1134782 CDS YP_006772427.1 410484881 13692809 5005799..5006824 1 NC_018650.1 COG1609 Transcriptional regulators; DNA-binding transcriptional regulator CytR 5006824 13692809 O3M_24115 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator CytR YP_006772427.1 5005799 D 1134782 CDS YP_006772428.1 410484882 13692810 5006916..5007875 1 NC_018650.1 COG3087 Cell division protein; cell division protein FtsN 5007875 13692810 O3M_24120 Escherichia coli O104:H4 str. 2009EL-2050 cell division protein FtsN YP_006772428.1 5006916 D 1134782 CDS YP_006772429.1 410484883 13692811 5007968..5008498 1 NC_018650.1 COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit; ATP-dependent protease subunit HslV 5008498 13692811 O3M_24125 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent protease subunit HslV YP_006772429.1 5007968 D 1134782 CDS YP_006772430.1 410484884 13692812 5008508..5009839 1 NC_018650.1 COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit; ATP-dependent protease ATP-binding subunit HslU 5009839 hslU 13692812 hslU Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent protease ATP-binding subunit HslU YP_006772430.1 5008508 D 1134782 CDS YP_006772431.1 410484885 13692813 5009906..5010832 1 NC_018650.1 COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 5010832 13692813 O3M_24135 Escherichia coli O104:H4 str. 2009EL-2050 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_006772431.1 5009906 D 1134782 CDS YP_006772432.1 410484886 13692814 5010925..5011410 1 NC_018650.1 COG0684 Demethylmenaquinone methyltransferase; ribonuclease activity regulator protein RraA 5011410 13692814 O3M_24140 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease activity regulator protein RraA YP_006772432.1 5010925 D 1134782 CDS YP_006772433.1 410484887 13692815 complement(5011495..5011734) 1 NC_018650.1 COG3074 Uncharacterized protein conserved in bacteria; septal ring assembly protein ZapB 5011734 13692815 O3M_24145 Escherichia coli O104:H4 str. 2009EL-2050 septal ring assembly protein ZapB YP_006772433.1 5011495 R 1134782 CDS YP_006772434.1 410484888 13692816 5012166..5013011 1 NC_018650.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator protein 5013011 13692816 O3M_24150 Escherichia coli O104:H4 str. 2009EL-2050 glycerol uptake facilitator protein YP_006772434.1 5012166 D 1134782 CDS YP_006772435.1 410484889 13692817 5013034..5014542 1 NC_018650.1 COG0554 Glycerol kinase; glycerol kinase 5014542 glpK 13692817 glpK Escherichia coli O104:H4 str. 2009EL-2050 glycerol kinase YP_006772435.1 5013034 D 1134782 CDS YP_006772436.1 410484890 13692818 5014678..5015688 1 NC_018650.1 COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; fructose 1,6-bisphosphatase II 5015688 glpX 13692818 glpX Escherichia coli O104:H4 str. 2009EL-2050 fructose 1,6-bisphosphatase II YP_006772436.1 5014678 D 1134782 CDS YP_006772437.1 410484891 13692819 5015785..5016531 1 NC_018650.1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; ferredoxin-NADP reductase 5016531 13692819 O3M_24165 Escherichia coli O104:H4 str. 2009EL-2050 ferredoxin-NADP reductase YP_006772437.1 5015785 D 1134782 CDS YP_006772438.1 410484892 13692820 complement(5016536..5016964) 1 NC_018650.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspD 5016964 13692820 O3M_24170 Escherichia coli O104:H4 str. 2009EL-2050 universal stress protein UspD YP_006772438.1 5016536 R 1134782 CDS YP_006772439.1 410484893 13692821 complement(5016991..5017290) 1 NC_018650.1 COG3691 Uncharacterized protein conserved in bacteria; hypothetical protein 5017290 13692821 O3M_24175 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772439.1 5016991 R 1134782 CDS YP_006772440.1 410484894 13692822 complement(5017502..5017942) 1 NC_018650.1 COG3152 Predicted membrane protein; inner membrane protein 5017942 13692822 O3M_24180 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006772440.1 5017502 R 1134782 CDS YP_006772441.1 410484895 13692823 5018043..5018642 1 NC_018650.1 hypothetical protein 5018642 13692823 O3M_24185 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772441.1 5018043 D 1134782 CDS YP_006772442.1 410484896 13692824 5018750..5019517 1 NC_018650.1 COG0149 Triosephosphate isomerase; triosephosphate isomerase 5019517 tpiA 13692824 tpiA Escherichia coli O104:H4 str. 2009EL-2050 triosephosphate isomerase YP_006772442.1 5018750 D 1134782 CDS YP_006772443.1 410484897 13692825 complement(5019572..5020327) 1 NC_018650.1 COG2134 CDP-diacylglycerol pyrophosphatase; CDP-diacylglycerol pyrophosphatase 5020327 13692825 O3M_24195 Escherichia coli O104:H4 str. 2009EL-2050 CDP-diacylglycerol pyrophosphatase YP_006772443.1 5019572 R 1134782 CDS YP_006772444.1 410484898 13692826 complement(5020434..5021423) 1 NC_018650.1 COG1613 ABC-type sulfate transport system, periplasmic component; sulfate transporter subunit 5021423 13692826 O3M_24200 Escherichia coli O104:H4 str. 2009EL-2050 sulfate transporter subunit YP_006772444.1 5020434 R 1134782 CDS YP_006772445.1 410484899 13692827 complement(5021743..5022705) 1 NC_018650.1 COG0205 6-phosphofructokinase; 6-phosphofructokinase 5022705 13692827 O3M_24205 Escherichia coli O104:H4 str. 2009EL-2050 6-phosphofructokinase YP_006772445.1 5021743 R 1134782 CDS YP_006772446.1 410484900 13692828 complement(5022886..5023788) 1 NC_018650.1 COG0053 Predicted Co/Zn/Cd cation transporters; ferrous iron efflux protein F 5023788 fieF 13692828 fieF Escherichia coli O104:H4 str. 2009EL-2050 ferrous iron efflux protein F YP_006772446.1 5022886 R 1134782 CDS YP_006772447.1 410484901 13692829 complement(5023937..5024437) 1 NC_018650.1 COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; repressor CpxP 5024437 cpxP 13692829 cpxP Escherichia coli O104:H4 str. 2009EL-2050 repressor CpxP YP_006772447.1 5023937 R 1134782 CDS YP_006772448.1 410484902 13692830 5024587..5025285 1 NC_018650.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator CpxR 5025285 13692830 O3M_24220 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator CpxR YP_006772448.1 5024587 D 1134782 CDS YP_006772449.1 410484903 13692831 5025282..5026655 1 NC_018650.1 COG0642 Signal transduction histidine kinase; two-component sensor protein 5026655 cpxA 13692831 cpxA Escherichia coli O104:H4 str. 2009EL-2050 two-component sensor protein YP_006772449.1 5025282 D 1134782 CDS YP_006772450.1 410484904 13692832 complement(5026761..5027435) 1 NC_018650.1 COG2258 Uncharacterized protein conserved in bacteria; 6-N-hydroxylaminopurine resistance protein 5027435 13692832 O3M_24230 Escherichia coli O104:H4 str. 2009EL-2050 6-N-hydroxylaminopurine resistance protein YP_006772450.1 5026761 R 1134782 CDS YP_006772451.1 410484905 13692833 complement(5027584..5028567) 1 NC_018650.1 2-keto-3-deoxygluconate permease 5028567 13692833 O3M_24235 Escherichia coli O104:H4 str. 2009EL-2050 2-keto-3-deoxygluconate permease YP_006772451.1 5027584 R 1134782 CDS YP_006772452.1 410484906 13692834 complement(5028827..5029447) 1 NC_018650.1 COG0605 Superoxide dismutase; superoxide dismutase 5029447 13692834 O3M_24240 Escherichia coli O104:H4 str. 2009EL-2050 superoxide dismutase YP_006772452.1 5028827 R 1134782 CDS YP_006772453.1 410484907 13692835 5029732..5030766 1 NC_018650.1 rhamnose-proton symporter 5030766 13692835 O3M_24245 Escherichia coli O104:H4 str. 2009EL-2050 rhamnose-proton symporter YP_006772453.1 5029732 D 1134782 CDS YP_006772454.1 410484908 13692836 complement(5030763..5031701) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator RhaR 5031701 13692836 O3M_24250 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator RhaR YP_006772454.1 5030763 R 1134782 CDS YP_006772455.1 410484909 13692837 complement(5031685..5032521) 1 NC_018650.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator RhaS 5032521 13692837 O3M_24255 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator RhaS YP_006772455.1 5031685 R 1134782 CDS YP_006772456.1 410484910 13692838 complement(5032581..5032730) 1 NC_018650.1 hypothetical protein 5032730 13692838 O3M_24260 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772456.1 5032581 R 1134782 CDS YP_006772457.1 410484911 13692839 5032809..5034278 1 NC_018650.1 COG1070 Sugar (pentulose and hexulose) kinases; rhamnulokinase 5034278 rhaB 13692839 rhaB Escherichia coli O104:H4 str. 2009EL-2050 rhamnulokinase YP_006772457.1 5032809 D 1134782 CDS YP_006772458.1 410484912 13692840 5034275..5035534 1 NC_018650.1 COG4806 L-rhamnose isomerase; L-rhamnose isomerase 5035534 13692840 O3M_24270 Escherichia coli O104:H4 str. 2009EL-2050 L-rhamnose isomerase YP_006772458.1 5034275 D 1134782 CDS YP_006772459.1 410484913 13692841 5035776..5036600 1 NC_018650.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; rhamnulose-1-phosphate aldolase 5036600 13692841 O3M_24275 Escherichia coli O104:H4 str. 2009EL-2050 rhamnulose-1-phosphate aldolase YP_006772459.1 5035776 D 1134782 CDS YP_006772460.1 410484914 13692842 5036610..5036924 1 NC_018650.1 COG3254 Uncharacterized conserved protein; L-rhamnose mutarotase 5036924 13692842 O3M_24280 Escherichia coli O104:H4 str. 2009EL-2050 L-rhamnose mutarotase YP_006772460.1 5036610 D 1134782 CDS YP_006772461.1 410484915 13692843 5037237..5037683 1 NC_018650.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); fructose-like phosphotransferase system subunit EIIA 5037683 13692843 O3M_24285 Escherichia coli O104:H4 str. 2009EL-2050 fructose-like phosphotransferase system subunit EIIA YP_006772461.1 5037237 D 1134782 CDS YP_006772462.1 410484916 13692844 5037694..5039145 1 NC_018650.1 COG1445 Phosphotransferase system fructose-specific component IIB; PTS system transporter subunits IIBC 5039145 13692844 O3M_24290 Escherichia coli O104:H4 str. 2009EL-2050 PTS system transporter subunits IIBC YP_006772462.1 5037694 D 1134782 CDS YP_006772463.1 410484917 13692845 5039135..5040205 1 NC_018650.1 COG1363 Cellulase M and related proteins; peptidase 5040205 13692845 O3M_24295 Escherichia coli O104:H4 str. 2009EL-2050 peptidase YP_006772463.1 5039135 D 1134782 CDS YP_006772464.1 410484918 13692846 5040205..5041953 1 NC_018650.1 COG3711 Transcriptional antiterminator; frv operon regulatory protein 5041953 13692846 O3M_24300 Escherichia coli O104:H4 str. 2009EL-2050 frv operon regulatory protein YP_006772464.1 5040205 D 1134782 CDS YP_006772465.1 410484919 13692847 complement(5042003..5043043) 1 NC_018650.1 hypothetical protein 5043043 13692847 O3M_24305 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772465.1 5042003 R 1134782 CDS YP_006772466.1 410484920 13692848 complement(5043196..5044029) 1 NC_018650.1 COG1526 Uncharacterized protein required for formate dehydrogenase activity; formate dehydrogenase accessory protein 5044029 13692848 O3M_24310 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase accessory protein YP_006772466.1 5043196 R 1134782 CDS YP_006772467.1 410484921 13692849 5044223..5044810 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-O, large subunit 5044810 13692849 O3M_24315 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-O, large subunit YP_006772467.1 5044223 D 1134782 CDS YP_006772468.1 410484922 13692850 5044859..5047273 1 NC_018650.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase-O, major subunit 5047273 13692850 O3M_24320 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-O, major subunit YP_006772468.1 5044859 D 1134782 CDS YP_006772469.1 410484923 13692851 5047286..5048188 1 NC_018650.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; formate dehydrogenase-O, iron-sulfur subunit 5048188 13692851 O3M_24325 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-O, iron-sulfur subunit YP_006772469.1 5047286 D 1134782 CDS YP_006772470.1 410484924 13692852 5048185..5048820 1 NC_018650.1 COG2864 Cytochrome b subunit of formate dehydrogenase; formate dehydrogenase-O subunit gamma 5048820 13692852 O3M_24330 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase-O subunit gamma YP_006772470.1 5048185 D 1134782 CDS YP_006772471.1 410484925 13692853 5048817..5049746 1 NC_018650.1 COG3058 Uncharacterized protein involved in formate dehydrogenase formation; formate dehydrogenase accessory protein FdhE 5049746 13692853 O3M_24335 Escherichia coli O104:H4 str. 2009EL-2050 formate dehydrogenase accessory protein FdhE YP_006772471.1 5048817 D 1134782 CDS YP_006772472.1 410484926 13692854 5049926..5050060 1 NC_018650.1 hypothetical protein 5050060 13692854 O3M_24340 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772472.1 5049926 D 1134782 CDS YP_006772473.1 410484927 13692855 complement(5050076..5050318) 1 NC_018650.1 COG1219 ATP-dependent protease Clp, ATPase subunit; hypothetical protein 5050318 13692855 O3M_24345 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772473.1 5050076 R 1134782 CDS YP_006772474.1 410484928 13692856 complement(5050538..5050756) 1 NC_018650.1 COG3905 Predicted transcriptional regulator; transcriptional regulator 5050756 13692856 O3M_24350 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772474.1 5050538 R 1134782 CDS YP_006772475.1 410484929 13692857 complement(5051342..5051632) 1 NC_018650.1 COG2944 Predicted transcriptional regulator; hypothetical protein 5051632 13692857 O3M_24355 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772475.1 5051342 R 1134782 CDS YP_006772476.1 410484930 13692858 complement(5051633..5051944) 1 NC_018650.1 hypothetical protein 5051944 13692858 O3M_24360 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772476.1 5051633 R 1134782 CDS YP_006772477.1 410484931 13692859 5052173..5053081 1 NC_018650.1 COG0657 Esterase/lipase; lipase 5053081 13692859 O3M_24365 Escherichia coli O104:H4 str. 2009EL-2050 lipase YP_006772477.1 5052173 D 1134782 CDS YP_006772478.1 410484932 13692860 complement(5053145..5054134) 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 5054134 13692860 O3M_24370 Escherichia coli O104:H4 str. 2009EL-2050 acetyltransferase YP_006772478.1 5053145 R 1134782 CDS YP_006772479.1 410484933 13692861 complement(5054131..5054568) 1 NC_018650.1 COG1490 D-Tyr-tRNAtyr deacylase; D-tyrosyl-tRNA(Tyr) deacylase 5054568 13692861 O3M_24375 Escherichia coli O104:H4 str. 2009EL-2050 D-tyrosyl-tRNA(Tyr) deacylase YP_006772479.1 5054131 R 1134782 CDS YP_006772480.1 410484934 13692862 complement(5054565..5055437) 1 NC_018650.1 COG1295 Predicted membrane protein; hypothetical protein 5055437 13692862 O3M_24380 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772480.1 5054565 R 1134782 CDS YP_006772481.1 410484935 13692863 complement(5055431..5056030) 1 NC_018650.1 COG1011 Predicted hydrolase (HAD superfamily); alpha-D-glucose-1-phosphatase 5056030 13692863 O3M_24385 Escherichia coli O104:H4 str. 2009EL-2050 alpha-D-glucose-1-phosphatase YP_006772481.1 5055431 R 1134782 CDS YP_006772482.1 410484936 13692864 complement(5056171..5057058) 1 NC_018650.1 COG2017 Galactose mutarotase and related enzymes; galactose mutarotase 5057058 13692864 O3M_24390 Escherichia coli O104:H4 str. 2009EL-2050 galactose mutarotase YP_006772482.1 5056171 R 1134782 CDS YP_006772483.1 410484937 13692865 complement(5057048..5058397) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 5058397 13692865 O3M_24395 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772483.1 5057048 R 1134782 CDS YP_006772484.1 410484938 13692866 complement(5058496..5059929) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 5059929 13692866 O3M_24400 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772484.1 5058496 R 1134782 CDS YP_006772485.1 410484939 13692867 complement(5059999..5061009) 1 NC_018650.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; dehydrogenase, GroES-like protein 5061009 13692867 O3M_24405 Escherichia coli O104:H4 str. 2009EL-2050 dehydrogenase, GroES-like protein YP_006772485.1 5059999 R 1134782 CDS YP_006772486.1 410484940 13692868 complement(5061042..5061929) 1 NC_018650.1 COG3684 Tagatose-1,6-bisphosphate aldolase; aldolase yihT 5061929 13692868 O3M_24410 Escherichia coli O104:H4 str. 2009EL-2050 aldolase yihT YP_006772486.1 5061042 R 1134782 CDS YP_006772487.1 410484941 13692869 complement(5061954..5062832) 1 NC_018650.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; NADH-dependent gamma-hydroxybutyrate dehydrogenase 5062832 13692869 O3M_24415 Escherichia coli O104:H4 str. 2009EL-2050 NADH-dependent gamma-hydroxybutyrate dehydrogenase YP_006772487.1 5061954 R 1134782 CDS YP_006772488.1 410484942 13692870 5063005..5063901 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; sugar kinase 5063901 13692870 O3M_24420 Escherichia coli O104:H4 str. 2009EL-2050 sugar kinase YP_006772488.1 5063005 D 1134782 CDS YP_006772489.1 410484943 13692871 5063941..5064729 1 NC_018650.1 COG1349 Transcriptional regulators of sugar metabolism; DEOR-type transcriptional regulator 5064729 13692871 O3M_24425 Escherichia coli O104:H4 str. 2009EL-2050 DEOR-type transcriptional regulator YP_006772489.1 5063941 D 1134782 CDS YP_006772490.1 410484944 13692872 complement(5064840..5066105) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; transporter 5066105 13692872 O3M_24430 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772490.1 5064840 R 1134782 CDS YP_006772491.1 410484945 13692873 complement(5066207..5067187) 1 NC_018650.1 COG1082 Sugar phosphate isomerases/epimerases; sugar phosphate isomerase 5067187 13692873 O3M_24435 Escherichia coli O104:H4 str. 2009EL-2050 sugar phosphate isomerase YP_006772491.1 5066207 R 1134782 CDS YP_006772492.1 410484946 13692874 complement(5067195..5067905) 1 NC_018650.1 COG2188 Transcriptional regulators; DNA-binding transcriptional regulator 5067905 13692874 O3M_24440 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YP_006772492.1 5067195 R 1134782 CDS YP_006772493.1 410484947 13692875 complement(5068122..5069945) 1 NC_018650.1 COG1217 Predicted membrane GTPase involved in stress response; GTP-binding protein 5069945 13692875 O3M_24445 Escherichia coli O104:H4 str. 2009EL-2050 GTP-binding protein YP_006772493.1 5068122 R 1134782 CDS YP_006772494.1 410484948 13692876 5070318..5071727 1 NC_018650.1 COG0174 Glutamine synthetase; glutamine synthetase 5071727 glnA 13692876 glnA Escherichia coli O104:H4 str. 2009EL-2050 glutamine synthetase YP_006772494.1 5070318 D 1134782 CDS YP_006772495.1 410484949 13692877 5072013..5073062 1 NC_018650.1 COG3852 Signal transduction histidine kinase, nitrogen specific; nitrogen regulation protein NR(II) 5073062 glnL 13692877 glnL Escherichia coli O104:H4 str. 2009EL-2050 nitrogen regulation protein NR(II) YP_006772495.1 5072013 D 1134782 CDS YP_006772496.1 410484950 13692878 5073074..5074483 1 NC_018650.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; nitrogen regulation protein NR(I) 5074483 glnG 13692878 glnG Escherichia coli O104:H4 str. 2009EL-2050 nitrogen regulation protein NR(I) YP_006772496.1 5073074 D 1134782 CDS YP_006772497.1 410484951 13692879 5074595..5074705 1 NC_018650.1 hypothetical protein 5074705 13692879 O3M_24465 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772497.1 5074595 D 1134782 CDS YP_006772498.1 410484952 13692880 complement(5074895..5076268) 1 NC_018650.1 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; coproporphyrinogen III oxidase 5076268 13692880 O3M_24470 Escherichia coli O104:H4 str. 2009EL-2050 coproporphyrinogen III oxidase YP_006772498.1 5074895 R 1134782 CDS YP_006772499.1 410484953 13692881 complement(5076457..5076966) 1 NC_018650.1 COG3078 Uncharacterized protein conserved in bacteria; GTPase activator 5076966 13692881 O3M_24475 Escherichia coli O104:H4 str. 2009EL-2050 GTPase activator YP_006772499.1 5076457 R 1134782 CDS YP_006772500.1 410484954 13692882 complement(5077174..5077251) 1 NC_018650.1 hypothetical protein 5077251 13692882 O3M_24480 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772500.1 5077174 R 1134782 CDS YP_006772501.1 410484955 13692883 5077548..5078180 1 NC_018650.1 COG0218 Predicted GTPase; GTP-binding protein YsxC 5078180 engB 13692883 engB Escherichia coli O104:H4 str. 2009EL-2050 GTP-binding protein YsxC YP_006772501.1 5077548 D 1134782 CDS YP_006772502.1 410484956 13692884 complement(5078562..5081348) 1 NC_018650.1 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); DNA polymerase I 5081348 13692884 O3M_24490 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase I YP_006772502.1 5078562 R 1134782 CDS YP_006772503.1 410484957 13692885 5081350..5081592 1 NC_018650.1 hypothetical protein 5081592 13692885 O3M_24495 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772503.1 5081350 D 1134782 CDS YP_006772504.1 410484958 13692886 5081712..5082644 1 NC_018650.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; acyltransferase 5082644 13692886 O3M_24500 Escherichia coli O104:H4 str. 2009EL-2050 acyltransferase YP_006772504.1 5081712 D 1134782 CDS YP_006772505.1 410484959 13692887 complement(5082685..5084115) 1 NC_018650.1 COG5339 Uncharacterized protein conserved in bacteria; hypothetical protein 5084115 13692887 O3M_24505 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772505.1 5082685 R 1134782 CDS YP_006772506.1 410484960 13692888 complement(5084270..5084896) 1 NC_018650.1 COG0526 Thiol-disulfide isomerase and thioredoxins; protein disulfide isomerase I 5084896 13692888 O3M_24510 Escherichia coli O104:H4 str. 2009EL-2050 protein disulfide isomerase I YP_006772506.1 5084270 R 1134782 CDS YP_006772507.1 410484961 13692889 complement(5084913..5085899) 1 NC_018650.1 COG2334 Putative homoserine kinase type II (protein kinase fold); serine/threonine protein kinase 5085899 13692889 O3M_24515 Escherichia coli O104:H4 str. 2009EL-2050 serine/threonine protein kinase YP_006772507.1 5084913 R 1134782 CDS YP_006772508.1 410484962 13692890 complement(5085976..5086245) 1 NC_018650.1 COG3084 Uncharacterized protein conserved in bacteria; hypothetical protein 5086245 13692890 O3M_24520 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772508.1 5085976 R 1134782 CDS YP_006772509.1 410484963 13692891 5086315..5086899 1 NC_018650.1 COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; molybdopterin-guanine dinucleotide biosynthesis protein MobA 5086899 mobA 13692891 mobA Escherichia coli O104:H4 str. 2009EL-2050 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_006772509.1 5086315 D 1134782 CDS YP_006772510.1 410484964 13692892 5086881..5087408 1 NC_018650.1 COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; molybdopterin-guanine dinucleotide biosynthesis protein MobB 5087408 13692892 O3M_24530 Escherichia coli O104:H4 str. 2009EL-2050 molybdopterin-guanine dinucleotide biosynthesis protein MobB YP_006772510.1 5086881 D 1134782 CDS YP_006772511.1 410484965 13692898 complement(5092993..5093538) 1 NC_018650.1 COG4635 Flavodoxin; protoporphyrinogen oxidase 5093538 hemG 13692898 hemG Escherichia coli O104:H4 str. 2009EL-2050 protoporphyrinogen oxidase YP_006772511.1 5092993 R 1134782 CDS YP_006772512.1 410484966 13692899 complement(5093550..5095001) 1 NC_018650.1 COG0168 Trk-type K+ transport systems, membrane components; potassium transporter 5095001 13692899 O3M_24540 Escherichia coli O104:H4 str. 2009EL-2050 potassium transporter YP_006772512.1 5093550 R 1134782 CDS YP_006772513.1 410484967 13692900 complement(5095040..5095654) 1 NC_018650.1 COG1739 Uncharacterized conserved protein; hypothetical protein 5095654 13692900 O3M_24545 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772513.1 5095040 R 1134782 CDS YP_006772514.1 410484968 13692901 complement(5095654..5096985) 1 NC_018650.1 COG0006 Xaa-Pro aminopeptidase; proline dipeptidase 5096985 13692901 O3M_24550 Escherichia coli O104:H4 str. 2009EL-2050 proline dipeptidase YP_006772514.1 5095654 R 1134782 CDS YP_006772515.1 410484969 13692902 5097175..5099364 1 NC_018650.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; multifunctional fatty acid oxidation complex subunit alpha 5099364 fadB 13692902 fadB Escherichia coli O104:H4 str. 2009EL-2050 multifunctional fatty acid oxidation complex subunit alpha YP_006772515.1 5097175 D 1134782 CDS YP_006772516.1 410484970 13692903 5099374..5100537 1 NC_018650.1 COG0183 Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase 5100537 fadA 13692903 fadA Escherichia coli O104:H4 str. 2009EL-2050 3-ketoacyl-CoA thiolase YP_006772516.1 5099374 D 1134782 CDS YP_006772517.1 410484971 13692904 complement(5100729..5101430) 1 NC_018650.1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; FMN reductase 5101430 fre 13692904 fre Escherichia coli O104:H4 str. 2009EL-2050 FMN reductase YP_006772517.1 5100729 R 1134782 CDS YP_006772518.1 410484972 13692905 complement(5101476..5102969) 1 NC_018650.1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 5102969 13692905 O3M_24570 Escherichia coli O104:H4 str. 2009EL-2050 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_006772518.1 5101476 R 1134782 CDS YP_006772519.1 410484973 13692906 5103136..5103624 1 NC_018650.1 COG0250 Transcription antiterminator; transcriptional activator RfaH 5103624 rfaH 13692906 rfaH Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator RfaH YP_006772519.1 5103136 D 1134782 CDS YP_006772520.1 410484974 13692907 complement(5103621..5104403) 1 NC_018650.1 COG0084 Mg-dependent DNase; DNase TatD 5104403 13692907 O3M_24580 Escherichia coli O104:H4 str. 2009EL-2050 DNase TatD YP_006772520.1 5103621 R 1134782 CDS YP_006772521.1 410484975 13692908 complement(5104445..5105221) 1 NC_018650.1 COG0805 Sec-independent protein secretion pathway component TatC; twin-arginine protein translocation system subunit TatC 5105221 13692908 O3M_24585 Escherichia coli O104:H4 str. 2009EL-2050 twin-arginine protein translocation system subunit TatC YP_006772521.1 5104445 R 1134782 CDS YP_006772522.1 410484976 13692909 complement(5105224..5105739) 1 NC_018650.1 COG1826 Sec-independent protein secretion pathway components; sec-independent translocase 5105739 13692909 O3M_24590 Escherichia coli O104:H4 str. 2009EL-2050 sec-independent translocase YP_006772522.1 5105224 R 1134782 CDS YP_006772523.1 410484977 13692910 complement(5105743..5106012) 1 NC_018650.1 COG1826 Sec-independent protein secretion pathway components; twin arginine translocase protein A 5106012 tatA 13692910 tatA Escherichia coli O104:H4 str. 2009EL-2050 twin arginine translocase protein A YP_006772523.1 5105743 R 1134782 CDS YP_006772524.1 410484978 13692911 complement(5106091..5107731) 1 NC_018650.1 COG0661 Predicted unusual protein kinase; ubiquinone biosynthesis protein UbiB 5107731 ubiB 13692911 ubiB Escherichia coli O104:H4 str. 2009EL-2050 ubiquinone biosynthesis protein UbiB YP_006772524.1 5106091 R 1134782 CDS YP_006772525.1 410484979 13692912 complement(5107728..5108333) 1 NC_018650.1 COG3165 Uncharacterized protein conserved in bacteria; hypothetical protein 5108333 13692912 O3M_24605 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772525.1 5107728 R 1134782 CDS YP_006772526.1 410484980 13692913 complement(5108347..5109102) 1 NC_018650.1 COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; ubiquinone/menaquinone biosynthesis methyltransferase 5109102 ubiE 13692913 ubiE Escherichia coli O104:H4 str. 2009EL-2050 ubiquinone/menaquinone biosynthesis methyltransferase YP_006772526.1 5108347 R 1134782 CDS YP_006772527.1 410484981 13692914 complement(5109197..5110624) 1 NC_018650.1 COG1322 Uncharacterized protein conserved in bacteria; DNA recombination protein RmuC 5110624 13692914 O3M_24615 Escherichia coli O104:H4 str. 2009EL-2050 DNA recombination protein RmuC YP_006772527.1 5109197 R 1134782 CDS YP_006772528.1 410484982 13692915 complement(5110765..5111526) 1 NC_018650.1 COG2820 Uridine phosphorylase; uridine phosphorylase 5111526 13692915 O3M_24620 Escherichia coli O104:H4 str. 2009EL-2050 uridine phosphorylase YP_006772528.1 5110765 R 1134782 CDS YP_006772529.1 410484983 13692916 5111788..5112603 1 NC_018650.1 COG0412 Dienelactone hydrolase and related enzymes; hydrolase 5112603 13692916 O3M_24625 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006772529.1 5111788 D 1134782 CDS YP_006772530.1 410484984 13692917 complement(5112642..5114903) 1 NC_018650.1 COG0620 Methionine synthase II (cobalamin-independent); 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 5114903 13692917 O3M_24630 Escherichia coli O104:H4 str. 2009EL-2050 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_006772530.1 5112642 R 1134782 CDS YP_006772531.1 410484985 13692918 5115021..5115974 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator MetR 5115974 13692918 O3M_24635 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator MetR YP_006772531.1 5115021 D 1134782 CDS YP_006772532.1 410484986 13692919 complement(5115862..5116761) 1 NC_018650.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 5116761 13692919 O3M_24640 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772532.1 5115862 R 1134782 CDS YP_006772533.1 410484987 13692920 complement(5116837..5117637) 1 NC_018650.1 COG0561 Predicted hydrolases of the HAD superfamily; hydrolase 5117637 13692920 O3M_24645 Escherichia coli O104:H4 str. 2009EL-2050 hydrolase YP_006772533.1 5116837 R 1134782 CDS YP_006772534.1 410484988 13692921 complement(5117645..5118667) 1 NC_018650.1 COG2267 Lysophospholipase; lysophospholipase L2 5118667 13692921 O3M_24650 Escherichia coli O104:H4 str. 2009EL-2050 lysophospholipase L2 YP_006772534.1 5117645 R 1134782 CDS YP_006772535.1 410484989 13692922 5118778..5119398 1 NC_018650.1 COG1280 Putative threonine efflux protein; homoserine/homoserine lactone efflux protein 5119398 rhtB 13692922 rhtB Escherichia coli O104:H4 str. 2009EL-2050 homoserine/homoserine lactone efflux protein YP_006772535.1 5118778 D 1134782 CDS YP_006772536.1 410484990 13692923 complement(5119460..5120080) 1 NC_018650.1 COG1280 Putative threonine efflux protein; threonine efflux system 5120080 13692923 O3M_24660 Escherichia coli O104:H4 str. 2009EL-2050 threonine efflux system YP_006772536.1 5119460 R 1134782 CDS YP_006772537.1 410484991 13692924 complement(5120144..5121973) 1 NC_018650.1 COG0514 Superfamily II DNA helicase; ATP-dependent DNA helicase RecQ 5121973 13692924 O3M_24665 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent DNA helicase RecQ YP_006772537.1 5120144 R 1134782 CDS YP_006772538.1 410484992 13692925 complement(5122106..5122975) 1 NC_018650.1 COG2829 Outer membrane phospholipase A; phospholipase A 5122975 13692925 O3M_24670 Escherichia coli O104:H4 str. 2009EL-2050 phospholipase A YP_006772538.1 5122106 R 1134782 CDS YP_006772539.1 410484993 13692926 5123140..5123607 1 NC_018650.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein 5123607 13692926 O3M_24675 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772539.1 5123140 D 1134782 CDS YP_006772540.1 410484994 13692927 5123659..5124546 1 NC_018650.1 COG2962 Predicted permeases; chloramphenical resistance permease RarD 5124546 13692927 O3M_24680 Escherichia coli O104:H4 str. 2009EL-2050 chloramphenical resistance permease RarD YP_006772540.1 5123659 D 1134782 CDS YP_006772541.1 410484995 13692928 complement(5124593..5124892) 1 NC_018650.1 hypothetical protein 5124892 13692928 O3M_24685 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772541.1 5124593 R 1134782 CDS YP_006772542.1 410484996 13692929 complement(5125538..5125657) 1 NC_018650.1 COG0598 Mg2+ and Co2+ transporters; magnesium/nickel/cobalt transporter CorA 5125657 13692929 O3M_24690 Escherichia coli O104:H4 str. 2009EL-2050 magnesium/nickel/cobalt transporter CorA YP_006772542.1 5125538 R 1134782 CDS YP_006772543.1 410484997 13692930 5125871..5126719 1 NC_018650.1 hypothetical protein 5126719 13692930 O3M_24695 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772543.1 5125871 D 1134782 CDS YP_006772544.1 410484998 13692931 5126716..5127207 1 NC_018650.1 hypothetical protein 5127207 13692931 O3M_24700 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772544.1 5126716 D 1134782 CDS YP_006772545.1 410484999 13692932 complement(5127249..5128199) 1 NC_018650.1 COG0598 Mg2+ and Co2+ transporters; magnesium/nickel/cobalt transporter CorA 5128199 13692932 O3M_24705 Escherichia coli O104:H4 str. 2009EL-2050 magnesium/nickel/cobalt transporter CorA YP_006772545.1 5127249 R 1134782 CDS YP_006772546.1 410485000 13692933 complement(5128443..5128577) 1 NC_018650.1 hypothetical protein 5128577 13692933 O3M_24710 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772546.1 5128443 R 1134782 CDS YP_006772547.1 410485001 13692934 5128569..5129333 1 NC_018650.1 COG3698 Predicted periplasmic protein; hypothetical protein 5129333 13692934 O3M_24715 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772547.1 5128569 D 1134782 CDS YP_006772548.1 410485002 13692935 complement(5129480..5131642) 1 NC_018650.1 COG0210 Superfamily I DNA and RNA helicases; DNA-dependent helicase II 5131642 uvrD 13692935 uvrD Escherichia coli O104:H4 str. 2009EL-2050 DNA-dependent helicase II YP_006772548.1 5129480 R 1134782 CDS YP_006772549.1 410485003 13692936 complement(5131726..5132442) 1 NC_018650.1 COG1011 Predicted hydrolase (HAD superfamily); flavin mononucleotide phosphatase 5132442 13692936 O3M_24725 Escherichia coli O104:H4 str. 2009EL-2050 flavin mononucleotide phosphatase YP_006772549.1 5131726 R 1134782 CDS YP_006772550.1 410485004 13692937 complement(5132442..5133338) 1 NC_018650.1 COG4973 Site-specific recombinase XerC; site-specific tyrosine recombinase XerC 5133338 xerC 13692937 xerC Escherichia coli O104:H4 str. 2009EL-2050 site-specific tyrosine recombinase XerC YP_006772550.1 5132442 R 1134782 CDS YP_006772551.1 410485005 13692938 complement(5133335..5134042) 1 NC_018650.1 COG3159 Uncharacterized protein conserved in bacteria; hypothetical protein 5134042 13692938 O3M_24735 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772551.1 5133335 R 1134782 CDS YP_006772552.1 410485006 13692939 complement(5134039..5134863) 1 NC_018650.1 COG0253 Diaminopimelate epimerase; diaminopimelate epimerase 5134863 dapF 13692939 dapF Escherichia coli O104:H4 str. 2009EL-2050 diaminopimelate epimerase YP_006772552.1 5134039 R 1134782 CDS YP_006772553.1 410485007 13692940 complement(5134900..5135103) 1 NC_018650.1 COG5567 Predicted small periplasmic lipoprotein; lipoprotein 5135103 13692940 O3M_24745 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006772553.1 5134900 R 1134782 CDS YP_006772554.1 410485008 13692941 5135453..5136007 1 NC_018650.1 hypothetical protein 5136007 13692941 O3M_24750 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772554.1 5135453 D 1134782 CDS YP_006772555.1 410485009 13692942 5136375..5137853 1 NC_018650.1 hypothetical protein 5137853 13692942 O3M_24755 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772555.1 5136375 D 1134782 CDS YP_006772556.1 410485010 13692943 5137850..5139175 1 NC_018650.1 hypothetical protein 5139175 13692943 O3M_24760 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772556.1 5137850 D 1134782 CDS YP_006772557.1 410485011 13692944 5139223..5139543 1 NC_018650.1 COG1965 Protein implicated in iron transport, frataxin homolog; frataxin-like protein 5139543 cyaY 13692944 cyaY Escherichia coli O104:H4 str. 2009EL-2050 frataxin-like protein YP_006772557.1 5139223 D 1134782 CDS YP_006772558.1 410485012 13692945 complement(5139583..5142129) 1 NC_018650.1 COG3072 Adenylate cyclase; adenylate cyclase 5142129 cyaA 13692945 cyaA Escherichia coli O104:H4 str. 2009EL-2050 adenylate cyclase YP_006772558.1 5139583 R 1134782 CDS YP_006772559.1 410485013 13692946 5142516..5143457 1 NC_018650.1 COG0181 Porphobilinogen deaminase; porphobilinogen deaminase 5143457 hemC 13692946 hemC Escherichia coli O104:H4 str. 2009EL-2050 porphobilinogen deaminase YP_006772559.1 5142516 D 1134782 CDS YP_006772560.1 410485014 13692947 5143454..5144194 1 NC_018650.1 COG1587 Uroporphyrinogen-III synthase; uroporphyrinogen-III synthase 5144194 hemD 13692947 hemD Escherichia coli O104:H4 str. 2009EL-2050 uroporphyrinogen-III synthase YP_006772560.1 5143454 D 1134782 CDS YP_006772561.1 410485015 13692948 5144216..5145451 1 NC_018650.1 COG2959 Uncharacterized enzyme of heme biosynthesis; uroporphyrinogen III C-methyltransferase 5145451 13692948 O3M_24785 Escherichia coli O104:H4 str. 2009EL-2050 uroporphyrinogen III C-methyltransferase YP_006772561.1 5144216 D 1134782 CDS YP_006772562.1 410485016 13692949 5145454..5146650 1 NC_018650.1 COG3071 Uncharacterized enzyme of heme biosynthesis; protoheme IX biogenesis protein 5146650 13692949 O3M_24790 Escherichia coli O104:H4 str. 2009EL-2050 protoheme IX biogenesis protein YP_006772562.1 5145454 D 1134782 CDS YP_006772563.1 410485017 13692950 5147329..5147490 1 NC_018650.1 hypothetical protein 5147490 13692950 O3M_24795 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772563.1 5147329 D 1134782 CDS YP_006772564.1 410485018 13692951 complement(5147574..5148809) 1 NC_018650.1 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); regulator of arylsulfatase activity 5148809 13692951 O3M_24800 Escherichia coli O104:H4 str. 2009EL-2050 regulator of arylsulfatase activity YP_006772564.1 5147574 R 1134782 CDS YP_006772565.1 410485019 13692956 complement(5149495..5150880) 1 NC_018650.1 COG1113 Gamma-aminobutyrate permease and related permeases; transporter 5150880 13692956 O3M_24805 Escherichia coli O104:H4 str. 2009EL-2050 transporter YP_006772565.1 5149495 R 1134782 CDS YP_006772566.1 410485020 13692957 complement(5151071..5151811) 1 NC_018650.1 COG1922 Teichoic acid biosynthesis proteins; UDP-N-acetyl-D-mannosaminuronic acid transferase 5151811 13692957 O3M_24810 Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_006772566.1 5151071 R 1134782 CDS YP_006772567.1 410485021 13692958 complement(5151814..5153166) 1 NC_018650.1 common antigen polymerase 5153166 13692958 O3M_24815 Escherichia coli O104:H4 str. 2009EL-2050 common antigen polymerase YP_006772567.1 5151814 R 1134782 CDS YP_006772568.1 410485022 13692959 complement(5153163..5154242) 1 NC_018650.1 4-alpha-L-fucosyltransferase 5154242 13692959 O3M_24820 Escherichia coli O104:H4 str. 2009EL-2050 4-alpha-L-fucosyltransferase YP_006772568.1 5153163 R 1134782 CDS YP_006772569.1 410485023 13692960 complement(5154239..5155489) 1 NC_018650.1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; O-antigen translocase 5155489 13692960 O3M_24825 Escherichia coli O104:H4 str. 2009EL-2050 O-antigen translocase YP_006772569.1 5154239 R 1134782 CDS YP_006772570.1 410485024 13692961 complement(5155491..5156621) 1 NC_018650.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 5156621 13692961 O3M_24830 Escherichia coli O104:H4 str. 2009EL-2050 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_006772570.1 5155491 R 1134782 CDS YP_006772571.1 410485025 13692962 complement(5156626..5157300) 1 NC_018650.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; TDP-fucosamine acetyltransferase 5157300 13692962 O3M_24835 Escherichia coli O104:H4 str. 2009EL-2050 TDP-fucosamine acetyltransferase YP_006772571.1 5156626 R 1134782 CDS YP_006772572.1 410485026 13692963 complement(5157278..5158159) 1 NC_018650.1 COG1209 dTDP-glucose pyrophosphorylase; glucose-1-phosphate thymidylyltransferase 5158159 13692963 O3M_24840 Escherichia coli O104:H4 str. 2009EL-2050 glucose-1-phosphate thymidylyltransferase YP_006772572.1 5157278 R 1134782 CDS YP_006772573.1 410485027 13692964 complement(5158178..5159245) 1 NC_018650.1 COG1088 dTDP-D-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 5159245 13692964 O3M_24845 Escherichia coli O104:H4 str. 2009EL-2050 dTDP-glucose 4,6-dehydratase YP_006772573.1 5158178 R 1134782 CDS YP_006772574.1 410485028 13692965 complement(5159245..5160507) 1 NC_018650.1 COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; UDP-N-acetyl-D-mannosamine dehydrogenase 5160507 wecC 13692965 wecC Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetyl-D-mannosamine dehydrogenase YP_006772574.1 5159245 R 1134782 CDS YP_006772575.1 410485029 13692966 complement(5160504..5161634) 1 NC_018650.1 COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 5161634 13692966 O3M_24855 Escherichia coli O104:H4 str. 2009EL-2050 UDP-N-acetylglucosamine 2-epimerase YP_006772575.1 5160504 R 1134782 CDS YP_006772576.1 410485030 13692967 complement(5161690..5162736) 1 NC_018650.1 COG3765 Chain length determinant protein; lipopolysaccharide biosynthesis protein WzzE 5162736 13692967 O3M_24860 Escherichia coli O104:H4 str. 2009EL-2050 lipopolysaccharide biosynthesis protein WzzE YP_006772576.1 5161690 R 1134782 CDS YP_006772577.1 410485031 13692968 complement(5162748..5163851) 1 NC_018650.1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 5163851 13692968 O3M_24865 Escherichia coli O104:H4 str. 2009EL-2050 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase YP_006772577.1 5162748 R 1134782 CDS YP_006772578.1 410485032 13692969 complement(5163863..5164081) 1 NC_018650.1 hypothetical protein 5164081 13692969 O3M_24870 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772578.1 5163863 R 1134782 CDS YP_006772579.1 410485033 13692970 complement(5164091..5165350) 1 NC_018650.1 COG1158 Transcription termination factor; transcription termination factor Rho 5165350 rho 13692970 rho Escherichia coli O104:H4 str. 2009EL-2050 transcription termination factor Rho YP_006772579.1 5164091 R 1134782 CDS YP_006772580.1 410485034 13692971 complement(5165435..5165536) 1 NC_018650.1 rho operon leader peptide 5165536 13692971 O3M_24880 Escherichia coli O104:H4 str. 2009EL-2050 rho operon leader peptide YP_006772580.1 5165435 R 1134782 CDS YP_006772581.1 410485035 13692972 complement(5165677..5166006) 1 NC_018650.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 5166006 trxA 13692972 trxA Escherichia coli O104:H4 str. 2009EL-2050 thioredoxin YP_006772581.1 5165677 R 1134782 CDS YP_006772582.1 410485036 13692973 5166137..5167402 1 NC_018650.1 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlB 5167402 13692973 O3M_24890 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent RNA helicase RhlB YP_006772582.1 5166137 D 1134782 CDS YP_006772583.1 410485037 13692974 5167536..5169020 1 NC_018650.1 COG0248 Exopolyphosphatase; guanosine pentaphosphate phosphohydrolase 5169020 13692974 O3M_24895 Escherichia coli O104:H4 str. 2009EL-2050 guanosine pentaphosphate phosphohydrolase YP_006772583.1 5167536 D 1134782 CDS YP_006772584.1 410485038 13692975 complement(5169067..5171088) 1 NC_018650.1 COG0210 Superfamily I DNA and RNA helicases; ATP-dependent DNA helicase Rep 5171088 13692975 O3M_24900 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent DNA helicase Rep YP_006772584.1 5169067 R 1134782 CDS YP_006772585.1 410485039 13692976 5171305..5171754 1 NC_018650.1 COG3692 Uncharacterized protein conserved in bacteria; hypothetical protein 5171754 13692976 O3M_24905 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772585.1 5171305 D 1134782 CDS YP_006772586.1 410485040 13692977 5171953..5172234 1 NC_018650.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; peptidyl-prolyl cis-trans isomerase C 5172234 13692977 O3M_24910 Escherichia coli O104:H4 str. 2009EL-2050 peptidyl-prolyl cis-trans isomerase C YP_006772586.1 5171953 D 1134782 CDS YP_006772587.1 410485041 13692978 complement(5172321..5173796) 1 NC_018650.1 COG0059 Ketol-acid reductoisomerase; ketol-acid reductoisomerase 5173796 13692978 O3M_24915 Escherichia coli O104:H4 str. 2009EL-2050 ketol-acid reductoisomerase YP_006772587.1 5172321 R 1134782 CDS YP_006772588.1 410485042 13692979 5173946..5174839 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator IlvY 5174839 13692979 O3M_24920 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator IlvY YP_006772588.1 5173946 D 1134782 CDS YP_006772589.1 410485043 13692980 complement(5174891..5176435) 1 NC_018650.1 COG1171 Threonine dehydratase; threonine dehydratase 5176435 13692980 O3M_24925 Escherichia coli O104:H4 str. 2009EL-2050 threonine dehydratase YP_006772589.1 5174891 R 1134782 CDS YP_006772590.1 410485044 13692981 complement(5176438..5178288) 1 NC_018650.1 COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxy-acid dehydratase 5178288 13692981 O3M_24930 Escherichia coli O104:H4 str. 2009EL-2050 dihydroxy-acid dehydratase YP_006772590.1 5176438 R 1134782 CDS YP_006772591.1 410485045 13692982 complement(5178353..5179282) 1 NC_018650.1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; branched-chain amino acid aminotransferase 5179282 13692982 O3M_24935 Escherichia coli O104:H4 str. 2009EL-2050 branched-chain amino acid aminotransferase YP_006772591.1 5178353 R 1134782 CDS YP_006772592.1 410485046 13692983 complement(5179302..5179565) 1 NC_018650.1 COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit; acetolactate synthase 2 regulatory subunit 5179565 ilvM 13692983 ilvM Escherichia coli O104:H4 str. 2009EL-2050 acetolactate synthase 2 regulatory subunit YP_006772592.1 5179302 R 1134782 CDS YP_006772593.1 410485047 13692984 complement(5179562..5181208) 1 NC_018650.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase 2 catalytic subunit 5181208 13692984 O3M_24945 Escherichia coli O104:H4 str. 2009EL-2050 acetolactate synthase 2 catalytic subunit YP_006772593.1 5179562 R 1134782 CDS YP_006772594.1 410485048 13692985 5181799..5183319 1 NC_018650.1 COG0606 Predicted ATPase with chaperone activity; ATP-dependent protease 5183319 13692985 O3M_24950 Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent protease YP_006772594.1 5181799 D 1134782 CDS YP_006772595.1 410485049 13692986 complement(5183344..5183682) 1 NC_018650.1 COG3085 Uncharacterized protein conserved in bacteria; hypothetical protein 5183682 13692986 O3M_24955 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772595.1 5183344 R 1134782 CDS YP_006772596.1 410485050 13692987 5183801..5184640 1 NC_018650.1 COG0583 Transcriptional regulator; transcriptional regulator HdfR 5184640 13692987 O3M_24960 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator HdfR YP_006772596.1 5183801 D 1134782 CDS YP_006772597.1 410485051 13692994 5190441..5191133 1 NC_018650.1 COG2186 Transcriptional regulators; transcriptional regulator 5191133 13692994 O3M_24965 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772597.1 5190441 D 1134782 CDS YP_006772598.1 410485052 13692996 5191156..5192583 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; multidrug or homocysteine efflux system 5192583 13692996 O3M_24970 Escherichia coli O104:H4 str. 2009EL-2050 multidrug or homocysteine efflux system YP_006772598.1 5191156 D 1134782 CDS YP_006772599.1 410485053 13692997 complement(5192549..5193541) 1 NC_018650.1 COG1609 Transcriptional regulators; transcriptional repressor RbsR 5193541 13692997 O3M_24975 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional repressor RbsR YP_006772599.1 5192549 R 1134782 CDS YP_006772600.1 410485054 13692998 complement(5193545..5194474) 1 NC_018650.1 COG0524 Sugar kinases, ribokinase family; ribokinase 5194474 13692998 O3M_24980 Escherichia coli O104:H4 str. 2009EL-2050 ribokinase YP_006772600.1 5193545 R 1134782 CDS YP_006772601.1 410485055 13692999 complement(5194600..5195490) 1 NC_018650.1 COG1879 ABC-type sugar transport system, periplasmic component; D-ribose transporter subunit RbsB 5195490 13692999 O3M_24985 Escherichia coli O104:H4 str. 2009EL-2050 D-ribose transporter subunit RbsB YP_006772601.1 5194600 R 1134782 CDS YP_006772602.1 410485056 13693000 complement(5195515..5196480) 1 NC_018650.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ribose ABC transporter permease 5196480 rbsC 13693000 rbsC Escherichia coli O104:H4 str. 2009EL-2050 ribose ABC transporter permease YP_006772602.1 5195515 R 1134782 CDS YP_006772603.1 410485057 13693001 complement(5196485..5197990) 1 NC_018650.1 COG1129 ABC-type sugar transport system, ATPase component; D-ribose transporter ATP-binding protein 5197990 13693001 O3M_24995 Escherichia coli O104:H4 str. 2009EL-2050 D-ribose transporter ATP-binding protein YP_006772603.1 5196485 R 1134782 CDS YP_006772604.1 410485058 13693002 complement(5197998..5198417) 1 NC_018650.1 COG1869 ABC-type ribose transport system, auxiliary component; D-ribose pyranase 5198417 13693002 O3M_25000 Escherichia coli O104:H4 str. 2009EL-2050 D-ribose pyranase YP_006772604.1 5197998 R 1134782 CDS YP_006772605.1 410485059 13693003 complement(5198584..5200452) 1 NC_018650.1 COG3158 K+ transporter; potassium transport protein Kup 5200452 trkD 13693003 trkD Escherichia coli O104:H4 str. 2009EL-2050 potassium transport protein Kup YP_006772605.1 5198584 R 1134782 CDS YP_006772606.1 410485060 13693004 5200675..5202171 1 NC_018650.1 COG0714 MoxR-like ATPases; regulatory ATPase RavA 5202171 13693004 O3M_25010 Escherichia coli O104:H4 str. 2009EL-2050 regulatory ATPase RavA YP_006772606.1 5200675 D 1134782 CDS YP_006772607.1 410485061 13693005 5202165..5203616 1 NC_018650.1 COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 5203616 13693005 O3M_25015 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772607.1 5202165 D 1134782 CDS YP_006772608.1 410485062 13693006 complement(5203621..5204613) 1 NC_018650.1 COG2502 Asparagine synthetase A; asparagine synthetase AsnA 5204613 13693006 O3M_25020 Escherichia coli O104:H4 str. 2009EL-2050 asparagine synthetase AsnA YP_006772608.1 5203621 R 1134782 CDS YP_006772609.1 410485063 13693007 5204765..5205223 1 NC_018650.1 COG1522 Transcriptional regulators; DNA-binding transcriptional regulator AsnC 5205223 13693007 O3M_25025 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator AsnC YP_006772609.1 5204765 D 1134782 CDS YP_006772610.1 410485064 13693008 5205313..5205756 1 NC_018650.1 COG0716 Flavodoxins; FMN-binding protein MioC 5205756 13693008 O3M_25030 Escherichia coli O104:H4 str. 2009EL-2050 FMN-binding protein MioC YP_006772610.1 5205313 D 1134782 CDS YP_006772611.1 410485065 13693009 5206135..5208024 1 NC_018650.1 COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 5208024 13693009 O3M_25035 Escherichia coli O104:H4 str. 2009EL-2050 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_006772611.1 5206135 D 1134782 CDS YP_006772612.1 410485066 13693010 5208088..5208711 1 NC_018650.1 COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; 16S rRNA methyltransferase GidB 5208711 gidB 13693010 gidB Escherichia coli O104:H4 str. 2009EL-2050 16S rRNA methyltransferase GidB YP_006772612.1 5208088 D 1134782 CDS YP_006772613.1 410485067 13693011 5209328..5209708 1 NC_018650.1 F0F1 ATP synthase subunit I 5209708 13693011 O3M_25045 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit I YP_006772613.1 5209328 D 1134782 CDS YP_006772614.1 410485068 13693012 5209717..5210532 1 NC_018650.1 COG0356 F0F1-type ATP synthase, subunit a; F0F1 ATP synthase subunit A 5210532 13693012 O3M_25050 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit A YP_006772614.1 5209717 D 1134782 CDS YP_006772615.1 410485069 13693013 5210579..5210818 1 NC_018650.1 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; F0F1 ATP synthase subunit C 5210818 13693013 O3M_25055 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit C YP_006772615.1 5210579 D 1134782 CDS YP_006772616.1 410485070 13693014 5210880..5211350 1 NC_018650.1 COG0711 F0F1-type ATP synthase, subunit b; F0F1 ATP synthase subunit B 5211350 13693014 O3M_25060 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit B YP_006772616.1 5210880 D 1134782 CDS YP_006772617.1 410485071 13693015 5211365..5211898 1 NC_018650.1 COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); F0F1 ATP synthase subunit delta 5211898 13693015 O3M_25065 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit delta YP_006772617.1 5211365 D 1134782 CDS YP_006772618.1 410485072 13693016 5211911..5213452 1 NC_018650.1 COG0056 F0F1-type ATP synthase, alpha subunit; F0F1 ATP synthase subunit alpha 5213452 13693016 O3M_25070 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit alpha YP_006772618.1 5211911 D 1134782 CDS YP_006772619.1 410485073 13693017 5213503..5214366 1 NC_018650.1 COG0224 F0F1-type ATP synthase, gamma subunit; F0F1 ATP synthase subunit gamma 5214366 13693017 O3M_25075 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit gamma YP_006772619.1 5213503 D 1134782 CDS YP_006772620.1 410485074 13693018 5214393..5215775 1 NC_018650.1 COG0055 F0F1-type ATP synthase, beta subunit; F0F1 ATP synthase subunit beta 5215775 13693018 O3M_25080 Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit beta YP_006772620.1 5214393 D 1134782 CDS YP_006772621.1 410485075 13693019 5215796..5216215 1 NC_018650.1 COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit); F0F1 ATP synthase subunit epsilon 5216215 atpC 13693019 atpC Escherichia coli O104:H4 str. 2009EL-2050 F0F1 ATP synthase subunit epsilon YP_006772621.1 5215796 D 1134782 CDS YP_006772622.1 410485076 13693020 5216566..5217936 1 NC_018650.1 COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 5217936 glmU 13693020 glmU Escherichia coli O104:H4 str. 2009EL-2050 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_006772622.1 5216566 D 1134782 CDS YP_006772623.1 410485077 13693021 5218098..5219927 1 NC_018650.1 COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; glucosamine--fructose-6-phosphate aminotransferase 5219927 13693021 O3M_25095 Escherichia coli O104:H4 str. 2009EL-2050 glucosamine--fructose-6-phosphate aminotransferase YP_006772623.1 5218098 D 1134782 CDS YP_006772624.1 410485078 13693022 5220229..5220801 1 NC_018650.1 COG3539 P pilus assembly protein, pilin FimA; fimbrial protein 5220801 lpfA 13693022 lpfA Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein YP_006772624.1 5220229 D 1134782 CDS YP_006772625.1 410485079 13693023 5220849..5221580 1 NC_018650.1 COG3121 P pilus assembly protein, chaperone PapD; fimbrial chaperone protein 5221580 lfpB 13693023 lfpB Escherichia coli O104:H4 str. 2009EL-2050 fimbrial chaperone protein YP_006772625.1 5220849 D 1134782 CDS YP_006772626.1 410485080 13693024 5221605..5224127 1 NC_018650.1 COG3188 P pilus assembly protein, porin PapC; outer membrane usher protein 5224127 13693024 O3M_25110 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane usher protein YP_006772626.1 5221605 D 1134782 CDS YP_006772627.1 410485081 13693025 5224138..5225211 1 NC_018650.1 fimbrial protein 5225211 13693025 O3M_25115 Escherichia coli O104:H4 str. 2009EL-2050 fimbrial protein YP_006772627.1 5224138 D 1134782 CDS YP_006772628.1 410485082 13693026 5225459..5226499 1 NC_018650.1 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 5226499 13693026 O3M_25120 Escherichia coli O104:H4 str. 2009EL-2050 phosphate ABC transporter substrate-binding protein YP_006772628.1 5225459 D 1134782 CDS YP_006772629.1 410485083 13693027 5226586..5227545 1 NC_018650.1 COG0573 ABC-type phosphate transport system, permease component; phosphate transporter permease subunit PstC 5227545 pstC 13693027 pstC Escherichia coli O104:H4 str. 2009EL-2050 phosphate transporter permease subunit PstC YP_006772629.1 5226586 D 1134782 CDS YP_006772630.1 410485084 13693028 5227545..5228435 1 NC_018650.1 COG0581 ABC-type phosphate transport system, permease component; phosphate transporter permease subunit PtsA 5228435 pstA 13693028 pstA Escherichia coli O104:H4 str. 2009EL-2050 phosphate transporter permease subunit PtsA YP_006772630.1 5227545 D 1134782 CDS YP_006772631.1 410485085 13693029 5228526..5229299 1 NC_018650.1 COG1117 ABC-type phosphate transport system, ATPase component; phosphate transporter ATP-binding protein 5229299 pstB 13693029 pstB Escherichia coli O104:H4 str. 2009EL-2050 phosphate transporter ATP-binding protein YP_006772631.1 5228526 D 1134782 CDS YP_006772632.1 410485086 13693030 5229314..5230039 1 NC_018650.1 COG0704 Phosphate uptake regulator; transcriptional regulator PhoU 5230039 13693030 O3M_25140 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator PhoU YP_006772632.1 5229314 D 1134782 CDS YP_006772633.1 410485087 13693031 5230325..5230768 1 NC_018650.1 COG3711 Transcriptional antiterminator; transcriptional antiterminator BglG 5230768 13693031 O3M_25145 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional antiterminator BglG YP_006772633.1 5230325 D 1134782 CDS YP_006772634.1 410485088 13693032 5230784..5231161 1 NC_018650.1 COG3711 Transcriptional antiterminator; transcriptional antiterminator BglG 5231161 13693032 O3M_25150 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional antiterminator BglG YP_006772634.1 5230784 D 1134782 CDS YP_006772635.1 410485089 13693033 5231295..5233172 1 NC_018650.1 COG1264 Phosphotransferase system IIB components; PTS system beta-glucoside-specific transporter subunit IIABC 5233172 13693033 O3M_25155 Escherichia coli O104:H4 str. 2009EL-2050 PTS system beta-glucoside-specific transporter subunit IIABC YP_006772635.1 5231295 D 1134782 CDS YP_006772636.1 410485090 13693034 5233191..5234585 1 NC_018650.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; cryptic phospho-beta-glucosidase B 5234585 13693034 O3M_25160 Escherichia coli O104:H4 str. 2009EL-2050 cryptic phospho-beta-glucosidase B YP_006772636.1 5233191 D 1134782 CDS YP_006772637.1 410485091 13693035 5234671..5236287 1 NC_018650.1 COG4580 Maltoporin (phage lambda and maltose receptor); carbohydrate-specific outer membrane porin, cryptic 5236287 13693035 O3M_25165 Escherichia coli O104:H4 str. 2009EL-2050 carbohydrate-specific outer membrane porin, cryptic YP_006772637.1 5234671 D 1134782 CDS YP_006772638.1 410485092 13693036 5236314..5237483 1 NC_018650.1 COG2382 Enterochelin esterase and related enzymes; xylanase 5237483 13693036 O3M_25170 Escherichia coli O104:H4 str. 2009EL-2050 xylanase YP_006772638.1 5236314 D 1134782 CDS YP_006772639.1 410485093 13693037 5237498..5238220 1 NC_018650.1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; 6-phosphogluconolactonase 5238220 13693037 O3M_25175 Escherichia coli O104:H4 str. 2009EL-2050 6-phosphogluconolactonase YP_006772639.1 5237498 D 1134782 CDS YP_006772640.1 410485094 13693038 complement(5238282..5238869) 1 NC_018650.1 COG3196 Uncharacterized protein conserved in bacteria; hypothetical protein 5238869 13693038 O3M_25180 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772640.1 5238282 R 1134782 CDS YP_006772641.1 410485095 13693039 complement(5238918..5239391) 1 NC_018650.1 inner membrane protein 5239391 13693039 O3M_25185 Escherichia coli O104:H4 str. 2009EL-2050 inner membrane protein YP_006772641.1 5238918 R 1134782 CDS YP_006772642.1 410485096 13693040 complement(5239458..5240123) 1 NC_018650.1 COG0637 Predicted phosphatase/phosphohexomutase; 6-phosphogluconate phosphatase 5240123 13693040 O3M_25190 Escherichia coli O104:H4 str. 2009EL-2050 6-phosphogluconate phosphatase YP_006772642.1 5239458 R 1134782 CDS YP_006772643.1 410485097 13693041 5240290..5241627 1 NC_018650.1 COG2252 Permeases; hypothetical protein 5241627 13693041 O3M_25195 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772643.1 5240290 D 1134782 CDS YP_006772644.1 410485098 13693042 complement(5241681..5242247) 1 NC_018650.1 COG0431 Predicted flavoprotein; hypothetical protein 5242247 13693042 O3M_25200 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772644.1 5241681 R 1134782 CDS YP_006772645.1 410485099 13693043 complement(5242269..5243018) 1 NC_018650.1 COG2091 Phosphopantetheinyl transferase; phosphopantetheinyl transferase 5243018 13693043 O3M_25205 Escherichia coli O104:H4 str. 2009EL-2050 phosphopantetheinyl transferase YP_006772645.1 5242269 R 1134782 CDS YP_006772646.1 410485100 13693044 complement(5243175..5244134) 1 NC_018650.1 COG0583 Transcriptional regulator; DNA-binding transcriptional regulator YidZ 5244134 13693044 O3M_25210 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding transcriptional regulator YidZ YP_006772646.1 5243175 R 1134782 CDS YP_006772647.1 410485101 13693045 complement(5244109..5245284) 1 NC_018650.1 COG0477 Permeases of the major facilitator superfamily; multidrug efflux system protein MdtL 5245284 13693045 O3M_25215 Escherichia coli O104:H4 str. 2009EL-2050 multidrug efflux system protein MdtL YP_006772647.1 5244109 R 1134782 CDS YP_006772648.1 410485102 13693046 complement(5245417..5246664) 1 NC_018650.1 COG0814 Amino acid permeases; tryptophan permease TnaB 5246664 13693046 O3M_25220 Escherichia coli O104:H4 str. 2009EL-2050 tryptophan permease TnaB YP_006772648.1 5245417 R 1134782 CDS YP_006772649.1 410485103 13693047 complement(5246755..5248170) 1 NC_018650.1 COG3033 Tryptophanase; tryptophanase/L-cysteine desulfhydrase, PLP-dependent 5248170 tnaA 13693047 tnaA Escherichia coli O104:H4 str. 2009EL-2050 tryptophanase/L-cysteine desulfhydrase, PLP-dependent YP_006772649.1 5246755 R 1134782 CDS YP_006772650.1 410485104 13693048 complement(5248391..5248465) 1 NC_018650.1 tryptophanase leader peptide 5248465 13693048 O3M_25230 Escherichia coli O104:H4 str. 2009EL-2050 tryptophanase leader peptide YP_006772650.1 5248391 R 1134782 CDS YP_006772651.1 410485105 13693049 complement(5248708..5250072) 1 NC_018650.1 COG0486 Predicted GTPase; tRNA modification GTPase TrmE 5250072 trmE 13693049 trmE Escherichia coli O104:H4 str. 2009EL-2050 tRNA modification GTPase TrmE YP_006772651.1 5248708 R 1134782 CDS YP_006772652.1 410485106 13693050 complement(5250178..5251824) 1 NC_018650.1 COG0706 Preprotein translocase subunit YidC; membrane protein insertase 5251824 13693050 O3M_25240 Escherichia coli O104:H4 str. 2009EL-2050 membrane protein insertase YP_006772652.1 5250178 R 1134782 CDS YP_006772653.1 410485107 13693051 complement(5251827..5252084) 1 NC_018650.1 COG0759 Uncharacterized conserved protein; hypothetical protein 5252084 13693051 O3M_25245 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772653.1 5251827 R 1134782 CDS YP_006772654.1 410485108 13693052 complement(5252048..5252407) 1 NC_018650.1 COG0594 RNase P protein component; ribonuclease P 5252407 rnpA 13693052 rnpA Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease P YP_006772654.1 5252048 R 1134782 CDS YP_006772655.1 410485109 13693053 complement(5252424..5252564) 1 NC_018650.1 COG0230 Ribosomal protein L34; 50S ribosomal protein L34 5252564 rpmH 13693053 rpmH Escherichia coli O104:H4 str. 2009EL-2050 50S ribosomal protein L34 YP_006772655.1 5252424 R 1134782 CDS YP_006772656.1 410485111 13693762 complement(join(108212..109274,1..3500)) 1 NC_018651.1 COG0840 Methyl-accepting chemotaxis protein; phage tail tape measure protein 3500 13693762 O3M_25494 Escherichia coli O104:H4 str. 2009EL-2050 phage tail tape measure protein YP_006772656.1 108212 R 1134782 CDS YP_006772657.1 410485112 13693763 complement(3508..3777) 1 NC_018651.1 hypothetical protein 3777 13693763 O3M_25499 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772657.1 3508 R 1134782 CDS YP_006772658.1 410485113 13693764 complement(3858..4175) 1 NC_018651.1 hypothetical protein 4175 13693764 O3M_25504 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772658.1 3858 R 1134782 CDS YP_006772659.1 410485114 13693765 complement(4243..4980) 1 NC_018651.1 COG5492 Bacterial surface proteins containing Ig-like domains; hypothetical protein 4980 13693765 O3M_25509 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772659.1 4243 R 1134782 CDS YP_006772660.1 410485115 13693766 complement(5054..5437) 1 NC_018651.1 hypothetical protein 5437 13693766 O3M_25514 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772660.1 5054 R 1134782 CDS YP_006772661.1 410485116 13693767 complement(5439..5912) 1 NC_018651.1 hypothetical protein 5912 13693767 O3M_25519 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772661.1 5439 R 1134782 CDS YP_006772662.1 410485117 13693768 complement(5903..6247) 1 NC_018651.1 hypothetical protein 6247 13693768 O3M_25524 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772662.1 5903 R 1134782 CDS YP_006772663.1 410485118 13693769 complement(6319..7152) 1 NC_018651.1 hypothetical protein 7152 13693769 O3M_25529 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772663.1 6319 R 1134782 CDS YP_006772664.1 410485119 13693770 complement(7152..7586) 1 NC_018651.1 hypothetical protein 7586 13693770 O3M_25534 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772664.1 7152 R 1134782 CDS YP_006772665.1 410485120 13693771 complement(7684..8604) 1 NC_018651.1 hypothetical protein 8604 13693771 O3M_25539 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772665.1 7684 R 1134782 CDS YP_006772666.1 410485121 13693772 complement(8630..9517) 1 NC_018651.1 hypothetical protein 9517 13693772 O3M_25544 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772666.1 8630 R 1134782 CDS YP_006772667.1 410485122 13693773 complement(9539..11113) 1 NC_018651.1 hypothetical protein 11113 13693773 O3M_25549 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772667.1 9539 R 1134782 CDS YP_006772668.1 410485123 13693774 complement(11140..12396) 1 NC_018651.1 hypothetical protein 12396 13693774 O3M_25554 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772668.1 11140 R 1134782 CDS YP_006772669.1 410485124 13693775 complement(12396..13028) 1 NC_018651.1 DNA-binding protein 13028 13693775 O3M_25559 Escherichia coli O104:H4 str. 2009EL-2050 DNA-binding protein YP_006772669.1 12396 R 1134782 CDS YP_006772670.1 410485125 13693776 complement(13224..13490) 1 NC_018651.1 hypothetical protein 13490 13693776 O3M_25564 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772670.1 13224 R 1134782 CDS YP_006772671.1 410485126 13693777 complement(13500..14390) 1 NC_018651.1 COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain; hypothetical protein 14390 13693777 O3M_25569 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772671.1 13500 R 1134782 CDS YP_006772672.1 410485127 13693778 complement(14387..15052) 1 NC_018651.1 COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain; ABC transporter ATP-binding protein 15052 13693778 O3M_25574 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein YP_006772672.1 14387 R 1134782 CDS YP_006772673.1 410485128 13693779 complement(15049..15717) 1 NC_018651.1 COG1475 Predicted transcriptional regulators; hypothetical protein 15717 13693779 O3M_25579 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772673.1 15049 R 1134782 CDS YP_006772674.1 410485129 13693780 complement(15717..16415) 1 NC_018651.1 COG1475 Predicted transcriptional regulators; hypothetical protein 16415 13693780 O3M_25584 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772674.1 15717 R 1134782 CDS YP_006772675.1 410485130 13693781 16480..18039 1 NC_018651.1 COG1061 DNA or RNA helicases of superfamily II; helicase 18039 13693781 O3M_25589 Escherichia coli O104:H4 str. 2009EL-2050 helicase YP_006772675.1 16480 D 1134782 CDS YP_006772676.1 410485131 13693782 18042..18320 1 NC_018651.1 hypothetical protein 18320 13693782 O3M_25594 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772676.1 18042 D 1134782 CDS YP_006772677.1 410485132 13693783 18386..18952 1 NC_018651.1 hypothetical protein 18952 13693783 O3M_25599 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772677.1 18386 D 1134782 CDS YP_006772678.1 410485133 13693784 19098..19586 1 NC_018651.1 hypothetical protein 19586 13693784 O3M_25604 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772678.1 19098 D 1134782 CDS YP_006772679.1 410485134 13693785 19602..20201 1 NC_018651.1 COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; hypothetical protein 20201 13693785 O3M_25609 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772679.1 19602 D 1134782 CDS YP_006772680.1 410485135 13693786 20198..20722 1 NC_018651.1 transcriptional regulator 20722 13693786 O3M_25614 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional regulator YP_006772680.1 20198 D 1134782 CDS YP_006772681.1 410485136 13693787 21011..21661 1 NC_018651.1 hypothetical protein 21661 13693787 O3M_25619 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772681.1 21011 D 1134782 CDS YP_006772682.1 410485137 13693788 21710..21913 1 NC_018651.1 hypothetical protein 21913 13693788 O3M_25624 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772682.1 21710 D 1134782 CDS YP_006772683.1 410485138 13693789 21935..22165 1 NC_018651.1 hypothetical protein 22165 13693789 O3M_25629 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772683.1 21935 D 1134782 CDS YP_006772684.1 410485139 13693790 complement(22781..23263) 1 NC_018651.1 hypothetical protein 23263 13693790 O3M_25634 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772684.1 22781 R 1134782 CDS YP_006772685.1 410485140 13693791 complement(23614..23988) 1 NC_018651.1 hypothetical protein 23988 13693791 O3M_25639 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772685.1 23614 R 1134782 CDS YP_006772686.1 410485141 13693792 complement(24107..24502) 1 NC_018651.1 hypothetical protein 24502 13693792 O3M_25644 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772686.1 24107 R 1134782 CDS YP_006772687.1 410485142 13693793 complement(24629..24940) 1 NC_018651.1 hypothetical protein 24940 13693793 O3M_25649 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772687.1 24629 R 1134782 CDS YP_006772688.1 410485143 13693794 complement(25095..25424) 1 NC_018651.1 hypothetical protein 25424 13693794 O3M_25654 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772688.1 25095 R 1134782 CDS YP_006772689.1 410485144 13693795 complement(25563..25781) 1 NC_018651.1 hypothetical protein 25781 13693795 O3M_25659 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772689.1 25563 R 1134782 CDS YP_006772690.1 410485145 13693796 complement(27322..27507) 1 NC_018651.1 hypothetical protein 27507 13693796 O3M_25664 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772690.1 27322 R 1134782 CDS YP_006772691.1 410485146 13693797 complement(27544..27843) 1 NC_018651.1 hypothetical protein 27843 13693797 O3M_25669 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772691.1 27544 R 1134782 CDS YP_006772692.1 410485147 13693798 complement(28005..30038) 1 NC_018651.1 COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase 30038 metG 13693798 metG Escherichia coli O104:H4 str. 2009EL-2050 methionyl-tRNA synthetase YP_006772692.1 28005 R 1134782 CDS YP_006772693.1 410485148 13693799 30196..31296 1 NC_018651.1 COG0489 ATPases involved in chromosome partitioning; antiporter inner membrane protein 31296 13693799 O3M_25679 Escherichia coli O104:H4 str. 2009EL-2050 antiporter inner membrane protein YP_006772693.1 30196 D 1134782 CDS YP_006772694.1 410485149 13693800 complement(31334..31723) 1 NC_018651.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); DNA repair protein 31723 13693800 O3M_25684 Escherichia coli O104:H4 str. 2009EL-2050 DNA repair protein YP_006772694.1 31334 R 1134782 CDS YP_006772695.1 410485150 13693801 complement(31896..32459) 1 NC_018651.1 hypothetical protein 32459 13693801 O3M_25689 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772695.1 31896 R 1134782 CDS YP_006772696.1 410485151 13693802 complement(32434..33285) 1 NC_018651.1 phage protein 33285 13693802 O3M_25694 Escherichia coli O104:H4 str. 2009EL-2050 phage protein YP_006772696.1 32434 R 1134782 CDS YP_006772697.1 410485152 13693803 complement(33285..33506) 1 NC_018651.1 hypothetical protein 33506 13693803 O3M_25699 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772697.1 33285 R 1134782 CDS YP_006772698.1 410485153 13693804 complement(33499..34074) 1 NC_018651.1 Eaa protein 34074 13693804 O3M_25704 Escherichia coli O104:H4 str. 2009EL-2050 Eaa protein YP_006772698.1 33499 R 1134782 CDS YP_006772699.1 410485154 13693805 complement(34076..34462) 1 NC_018651.1 hypothetical protein 34462 13693805 O3M_25709 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772699.1 34076 R 1134782 CDS YP_006772700.1 410485155 13693806 complement(34473..34736) 1 NC_018651.1 hypothetical protein 34736 13693806 O3M_25714 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772700.1 34473 R 1134782 CDS YP_006772701.1 410485156 13693807 complement(34738..35259) 1 NC_018651.1 hypothetical protein 35259 13693807 O3M_25719 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772701.1 34738 R 1134782 CDS YP_006772702.1 410485157 13693808 complement(35256..35579) 1 NC_018651.1 COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease ATP-binding subunit ClpX 35579 clpX 13693808 clpX Escherichia coli O104:H4 str. 2009EL-2050 ATP-dependent protease ATP-binding subunit ClpX YP_006772702.1 35256 R 1134782 CDS YP_006772703.1 410485158 13693809 complement(35581..36111) 1 NC_018651.1 COG1196 Chromosome segregation ATPases; hypothetical protein 36111 13693809 O3M_25729 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772703.1 35581 R 1134782 CDS YP_006772704.1 410485159 13693810 complement(36098..36352) 1 NC_018651.1 hypothetical protein 36352 13693810 O3M_25734 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772704.1 36098 R 1134782 CDS YP_006772705.1 410485160 13693811 complement(36349..36891) 1 NC_018651.1 hypothetical protein 36891 13693811 O3M_25739 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772705.1 36349 R 1134782 CDS YP_006772706.1 410485161 13693812 complement(37030..37410) 1 NC_018651.1 hypothetical protein 37410 13693812 O3M_25744 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772706.1 37030 R 1134782 CDS YP_006772707.1 410485162 13693813 complement(37410..38114) 1 NC_018651.1 hypothetical protein 38114 13693813 O3M_25749 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772707.1 37410 R 1134782 CDS YP_006772708.1 410485163 13693814 complement(38176..39861) 1 NC_018651.1 COG0827 Adenine-specific DNA methylase; DNA modification methylase 39861 13693814 O3M_25754 Escherichia coli O104:H4 str. 2009EL-2050 DNA modification methylase YP_006772708.1 38176 R 1134782 CDS YP_006772709.1 410485164 13693815 complement(39965..40579) 1 NC_018651.1 hypothetical protein 40579 13693815 O3M_25759 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772709.1 39965 R 1134782 CDS YP_006772710.1 410485165 13693816 complement(40921..41490) 1 NC_018651.1 hypothetical protein 41490 13693816 O3M_25764 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772710.1 40921 R 1134782 CDS YP_006772711.1 410485166 13693817 complement(41630..41788) 1 NC_018651.1 hypothetical protein 41788 13693817 O3M_25769 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772711.1 41630 R 1134782 CDS YP_006772712.1 410485167 13693818 complement(41788..42213) 1 NC_018651.1 COG3793 Tellurite resistance protein; hypothetical protein 42213 13693818 O3M_25774 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772712.1 41788 R 1134782 CDS YP_006772713.1 410485168 13693819 complement(42307..42495) 1 NC_018651.1 hypothetical protein 42495 13693819 O3M_25779 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772713.1 42307 R 1134782 CDS YP_006772714.1 410485169 13693820 complement(42492..42743) 1 NC_018651.1 hypothetical protein 42743 13693820 O3M_25784 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772714.1 42492 R 1134782 CDS YP_006772715.1 410485170 13693821 complement(43145..43738) 1 NC_018651.1 COG0328 Ribonuclease HI; ribonuclease H 43738 13693821 O3M_25789 Escherichia coli O104:H4 str. 2009EL-2050 ribonuclease H YP_006772715.1 43145 R 1134782 CDS YP_006772716.1 410485171 13693822 complement(44320..44550) 1 NC_018651.1 hypothetical protein 44550 13693822 O3M_25794 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772716.1 44320 R 1134782 CDS YP_006772717.1 410485172 13693823 complement(44738..45331) 1 NC_018651.1 hypothetical protein 45331 13693823 O3M_25799 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772717.1 44738 R 1134782 CDS YP_006772718.1 410485173 13693824 complement(45514..46323) 1 NC_018651.1 hypothetical protein 46323 13693824 O3M_25804 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772718.1 45514 R 1134782 CDS YP_006772719.1 410485174 13693825 complement(46484..47041) 1 NC_018651.1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; hypothetical protein 47041 13693825 O3M_25809 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772719.1 46484 R 1134782 CDS YP_006772720.1 410485175 13693826 complement(47051..47470) 1 NC_018651.1 hypothetical protein 47470 13693826 O3M_25814 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772720.1 47051 R 1134782 CDS YP_006772721.1 410485176 13693827 complement(47532..48176) 1 NC_018651.1 COG0563 Adenylate kinase and related kinases; hypothetical protein 48176 13693827 O3M_25819 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772721.1 47532 R 1134782 CDS YP_006772722.1 410485177 13693828 complement(48176..48652) 1 NC_018651.1 COG0262 Dihydrofolate reductase; dihydrofolate reductase 48652 13693828 O3M_25824 Escherichia coli O104:H4 str. 2009EL-2050 dihydrofolate reductase YP_006772722.1 48176 R 1134782 CDS YP_006772723.1 410485178 13693829 complement(48649..49050) 1 NC_018651.1 COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain; hypothetical protein 49050 13693829 O3M_25829 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772723.1 48649 R 1134782 CDS YP_006772724.1 410485179 13693830 complement(49064..50167) 1 NC_018651.1 COG0207 Thymidylate synthase; thymidylate synthase 50167 13693830 O3M_25834 Escherichia coli O104:H4 str. 2009EL-2050 thymidylate synthase YP_006772724.1 49064 R 1134782 CDS YP_006772725.1 410485180 13693831 complement(50335..51204) 1 NC_018651.1 hypothetical protein 51204 13693831 O3M_25839 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772725.1 50335 R 1134782 CDS YP_006772726.1 410485181 13693703 complement(51282..52424) 1 NC_018651.1 COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta 52424 nrdB 13693703 nrdB Escherichia coli O104:H4 str. 2009EL-2050 ribonucleotide-diphosphate reductase subunit beta YP_006772726.1 51282 R 1134782 CDS YP_006772727.1 410485182 13693704 complement(52533..54848) 1 NC_018651.1 COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha 54848 13693704 O3M_25849 Escherichia coli O104:H4 str. 2009EL-2050 ribonucleotide-diphosphate reductase subunit alpha YP_006772727.1 52533 R 1134782 CDS YP_006772728.1 410485183 13693705 complement(54922..55491) 1 NC_018651.1 COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit; hypothetical protein 55491 13693705 O3M_25854 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772728.1 54922 R 1134782 CDS YP_006772729.1 410485184 13693706 complement(55501..56244) 1 NC_018651.1 hypothetical protein 56244 13693706 O3M_25859 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772729.1 55501 R 1134782 CDS YP_006772730.1 410485185 13693707 complement(56234..58150) 1 NC_018651.1 COG0419 ATPase involved in DNA repair; exonuclease subunit 2 58150 13693707 O3M_25864 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease subunit 2 YP_006772730.1 56234 R 1134782 CDS YP_006772731.1 410485186 13693708 complement(58380..59465) 1 NC_018651.1 COG0420 DNA repair exonuclease; hypothetical protein 59465 13693708 O3M_25869 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772731.1 58380 R 1134782 CDS YP_006772732.1 410485187 13693709 complement(59720..60364) 1 NC_018651.1 hypothetical protein 60364 13693709 O3M_25874 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772732.1 59720 R 1134782 CDS YP_006772733.1 410485188 13693710 60686..61780 1 NC_018651.1 RepA/RepC 61780 13693710 O3M_25879 Escherichia coli O104:H4 str. 2009EL-2050 RepA/RepC YP_006772733.1 60686 D 1134782 CDS YP_006772734.1 410485189 13693711 complement(62360..62572) 1 NC_018651.1 hypothetical protein 62572 13693711 O3M_25884 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772734.1 62360 R 1134782 CDS YP_006772735.1 410485190 13693712 complement(62572..62907) 1 NC_018651.1 hypothetical protein 62907 13693712 O3M_25889 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772735.1 62572 R 1134782 CDS YP_006772736.1 410485191 13693713 complement(62904..63083) 1 NC_018651.1 hypothetical protein 63083 13693713 O3M_25894 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772736.1 62904 R 1134782 CDS YP_006772737.1 410485192 13693714 complement(63123..63398) 1 NC_018651.1 hypothetical protein 63398 13693714 O3M_25899 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772737.1 63123 R 1134782 CDS YP_006772738.1 410485193 13693715 complement(63454..63879) 1 NC_018651.1 hypothetical protein 63879 13693715 O3M_25904 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772738.1 63454 R 1134782 CDS YP_006772739.1 410485194 13693716 complement(63941..64330) 1 NC_018651.1 hypothetical protein 64330 13693716 O3M_25909 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772739.1 63941 R 1134782 CDS YP_006772740.1 410485195 13693717 complement(64351..65091) 1 NC_018651.1 hypothetical protein 65091 13693717 O3M_25914 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772740.1 64351 R 1134782 CDS YP_006772741.1 410485196 13693718 complement(65139..65963) 1 NC_018651.1 hypothetical protein 65963 13693718 O3M_25919 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772741.1 65139 R 1134782 CDS YP_006772742.1 410485197 13693719 complement(66059..66889) 1 NC_018651.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; lipoprotein 66889 13693719 O3M_25924 Escherichia coli O104:H4 str. 2009EL-2050 lipoprotein YP_006772742.1 66059 R 1134782 CDS YP_006772743.1 410485198 13693720 complement(66893..67093) 1 NC_018651.1 hypothetical protein 67093 13693720 O3M_25929 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772743.1 66893 R 1134782 CDS YP_006772744.1 410485199 13693721 complement(67186..68259) 1 NC_018651.1 COG0468 RecA/RadA recombinase; recombinase 68259 13693721 O3M_25934 Escherichia coli O104:H4 str. 2009EL-2050 recombinase YP_006772744.1 67186 R 1134782 CDS YP_006772745.1 410485200 13693722 complement(68262..68528) 1 NC_018651.1 hypothetical protein 68528 13693722 O3M_25939 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772745.1 68262 R 1134782 CDS YP_006772746.1 410485201 13693723 complement(68528..69472) 1 NC_018651.1 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); exonuclease 69472 13693723 O3M_25944 Escherichia coli O104:H4 str. 2009EL-2050 exonuclease YP_006772746.1 68528 R 1134782 CDS YP_006772747.1 410485202 13693724 complement(69533..70561) 1 NC_018651.1 regulator 70561 13693724 O3M_25949 Escherichia coli O104:H4 str. 2009EL-2050 regulator YP_006772747.1 69533 R 1134782 CDS YP_006772748.1 410485203 13693725 complement(70679..71110) 1 NC_018651.1 hypothetical protein 71110 13693725 O3M_25954 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772748.1 70679 R 1134782 CDS YP_006772749.1 410485204 13693726 complement(71236..74754) 1 NC_018651.1 COG0587 DNA polymerase III, alpha subunit; DNA polymerase III 74754 13693726 O3M_25959 Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase III YP_006772749.1 71236 R 1134782 CDS YP_006772750.1 410485205 13693727 complement(74935..76170) 1 NC_018651.1 COG0714 MoxR-like ATPases; porphyrin biosynthetic protein 76170 13693727 O3M_25964 Escherichia coli O104:H4 str. 2009EL-2050 porphyrin biosynthetic protein YP_006772750.1 74935 R 1134782 CDS YP_006772751.1 410485206 13693728 complement(76266..78374) 1 NC_018651.1 COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase); porphyrin biosynthetic protein 78374 13693728 O3M_25969 Escherichia coli O104:H4 str. 2009EL-2050 porphyrin biosynthetic protein YP_006772751.1 76266 R 1134782 CDS YP_006772752.1 410485207 13693729 complement(78475..78687) 1 NC_018651.1 hypothetical protein 78687 13693729 O3M_25974 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772752.1 78475 R 1134782 CDS YP_006772753.1 410485208 13693730 78935..79321 1 NC_018651.1 hypothetical protein 79321 13693730 O3M_25979 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772753.1 78935 D 1134782 CDS YP_006772754.1 410485209 13693731 complement(79316..80419) 1 NC_018651.1 COG0582 Integrase; integrase 80419 13693731 O3M_25984 Escherichia coli O104:H4 str. 2009EL-2050 integrase YP_006772754.1 79316 R 1134782 CDS YP_006772755.1 410485210 13693732 complement(80627..82540) 1 NC_018651.1 hypothetical protein 82540 13693732 O3M_25989 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772755.1 80627 R 1134782 CDS YP_006772756.1 410485211 13693737 complement(84366..84656) 1 NC_018651.1 hypothetical protein 84656 13693737 O3M_25999 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772756.1 84366 R 1134782 CDS YP_006772757.1 410485212 13693738 complement(84653..84805) 1 NC_018651.1 hypothetical protein 84805 13693738 O3M_26004 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772757.1 84653 R 1134782 CDS YP_006772758.1 410485213 13693739 complement(84802..85017) 1 NC_018651.1 hypothetical protein 85017 13693739 O3M_26009 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772758.1 84802 R 1134782 CDS YP_006772759.1 410485214 13693740 complement(85001..85180) 1 NC_018651.1 hypothetical protein 85180 13693740 O3M_26014 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772759.1 85001 R 1134782 CDS YP_006772760.1 410485215 13693741 complement(85177..86499) 1 NC_018651.1 DNA ligase 86499 13693741 O3M_26019 Escherichia coli O104:H4 str. 2009EL-2050 DNA ligase YP_006772760.1 85177 R 1134782 CDS YP_006772761.1 410485216 13693742 complement(86496..86753) 1 NC_018651.1 hypothetical protein 86753 13693742 O3M_26024 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772761.1 86496 R 1134782 CDS YP_006772762.1 410485217 13693743 complement(87034..87816) 1 NC_018651.1 hypothetical protein 87816 13693743 O3M_26029 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772762.1 87034 R 1134782 CDS YP_006772763.1 410485218 13693744 complement(87892..89073) 1 NC_018651.1 COG0358 DNA primase (bacterial type); hypothetical protein 89073 13693744 O3M_26034 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772763.1 87892 R 1134782 CDS YP_006772764.1 410485219 13693745 complement(89155..90495) 1 NC_018651.1 COG0305 Replicative DNA helicase; DNA helicase 90495 13693745 O3M_26039 Escherichia coli O104:H4 str. 2009EL-2050 DNA helicase YP_006772764.1 89155 R 1134782 CDS YP_006772765.1 410485220 13693746 complement(90539..91279) 1 NC_018651.1 hypothetical protein 91279 13693746 O3M_26044 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772765.1 90539 R 1134782 CDS YP_006772766.1 410485221 13693747 complement(91460..93154) 1 NC_018651.1 hypothetical protein 93154 13693747 O3M_26049 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772766.1 91460 R 1134782 CDS YP_006772767.1 410485222 13693748 complement(93206..93565) 1 NC_018651.1 hypothetical protein 93565 13693748 O3M_26054 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772767.1 93206 R 1134782 CDS YP_006772768.1 410485223 13693749 complement(93565..94233) 1 NC_018651.1 COG1192 ATPases involved in chromosome partitioning; hypothetical protein 94233 13693749 O3M_26059 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772768.1 93565 R 1134782 CDS YP_006772769.1 410485224 13693750 94552..94821 1 NC_018651.1 COG4453 Uncharacterized protein conserved in bacteria; hypothetical protein 94821 13693750 O3M_26064 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772769.1 94552 D 1134782 CDS YP_006772770.1 410485225 13693751 94829..95350 1 NC_018651.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 95350 13693751 O3M_26069 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772770.1 94829 D 1134782 CDS YP_006772771.1 410485226 13693752 complement(95518..95769) 1 NC_018651.1 hypothetical protein 95769 13693752 O3M_26074 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772771.1 95518 R 1134782 CDS YP_006772772.1 410485227 13693753 complement(95771..96463) 1 NC_018651.1 hypothetical protein 96463 13693753 O3M_26079 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772772.1 95771 R 1134782 CDS YP_006772773.1 410485228 13693754 complement(96477..96800) 1 NC_018651.1 hypothetical protein 96800 13693754 O3M_26084 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772773.1 96477 R 1134782 CDS YP_006772774.1 410485229 13693755 complement(96898..97410) 1 NC_018651.1 hypothetical protein 97410 13693755 O3M_26089 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772774.1 96898 R 1134782 CDS YP_006772775.1 410485230 13693756 complement(97496..100867) 1 NC_018651.1 phage lambda-related protein 100867 13693756 O3M_26094 Escherichia coli O104:H4 str. 2009EL-2050 phage lambda-related protein YP_006772775.1 97496 R 1134782 CDS YP_006772776.1 410485231 13693757 complement(100962..105668) 1 NC_018651.1 COG4733 Phage-related protein, tail component; phage tail protein 105668 13693757 O3M_26099 Escherichia coli O104:H4 str. 2009EL-2050 phage tail protein YP_006772776.1 100962 R 1134782 CDS YP_006772777.1 410485232 13693758 complement(105685..106275) 1 NC_018651.1 COG4723 Phage-related protein, tail component; phage tail protein 106275 13693758 O3M_26104 Escherichia coli O104:H4 str. 2009EL-2050 phage tail protein YP_006772777.1 105685 R 1134782 CDS YP_006772778.1 410485233 13693759 complement(106263..107060) 1 NC_018651.1 COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; phage tail protein 107060 13693759 O3M_26109 Escherichia coli O104:H4 str. 2009EL-2050 phage tail protein YP_006772778.1 106263 R 1134782 CDS YP_006772779.1 410485234 13693760 complement(107053..107751) 1 NC_018651.1 COG4672 Phage-related protein; phage lambda-related tail protein L 107751 13693760 O3M_26114 Escherichia coli O104:H4 str. 2009EL-2050 phage lambda-related tail protein L YP_006772779.1 107053 R 1134782 CDS YP_006772780.1 410485235 13693761 complement(107834..108169) 1 NC_018651.1 COG4718 Phage-related protein; minor tail fiber protein M 108169 13693761 O3M_26119 Escherichia coli O104:H4 str. 2009EL-2050 minor tail fiber protein M YP_006772780.1 107834 R 1134782 CDS YP_006772781.1 410480050 13696061 3..515 1 NC_018652.1 replication protein 515 13696061 O3M_26617 Escherichia coli O104:H4 str. 2009EL-2050 replication protein YP_006772781.1 3 D 1134782 CDS YP_006772782.1 410480051 13696060 complement(571..1047) 1 NC_018652.1 COG4565 Response regulator of citrate/malate metabolism; plasmid replication protein 1047 13696060 O3M_26622 Escherichia coli O104:H4 str. 2009EL-2050 plasmid replication protein YP_006772782.1 571 R 1134782 CDS YP_006772784.1 410480053 13696106 join(73478..74213,1..71) 1 NC_018654.1 COG0582 Integrase; resolvase (protein D) 71 13696106 O3M_26612 Escherichia coli O104:H4 str. 2009EL-2050 resolvase (protein D) YP_006772784.1 73478 D 1134782 CDS YP_006772785.1 410480054 13696105 250..894 1 NC_018654.1 COG1192 ATPases involved in chromosome partitioning; chromosome partitioning ATPase 894 13696105 O3M_26137 Escherichia coli O104:H4 str. 2009EL-2050 chromosome partitioning ATPase YP_006772785.1 250 D 1134782 CDS YP_006772786.1 410480055 13696107 981..1289 1 NC_018654.1 chaperonin 1289 13696107 O3M_26142 Escherichia coli O104:H4 str. 2009EL-2050 chaperonin YP_006772786.1 981 D 1134782 CDS YP_006772787.1 410480056 13696108 1703..2683 1 NC_018654.1 COG0443 Molecular chaperone; Plasmid segregation protein (ParA locus) 2683 13696108 O3M_26147 Escherichia coli O104:H4 str. 2009EL-2050 Plasmid segregation protein (ParA locus) YP_006772787.1 1703 D 1134782 CDS YP_006772788.1 410480057 13696109 2676..3092 1 NC_018654.1 hypothetical protein 3092 13696109 O3M_26152 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772788.1 2676 D 1134782 CDS YP_006772789.1 410480058 13696110 complement(3172..3330) 1 NC_018654.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC 3330 umuC 13696110 umuC Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase V subunit UmuC YP_006772789.1 3172 R 1134782 CDS YP_006772790.1 410480059 13696111 complement(3468..4367) 1 NC_018654.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase V subunit UmuC 4367 umuC 13696111 umuC Escherichia coli O104:H4 str. 2009EL-2050 DNA polymerase V subunit UmuC YP_006772790.1 3468 R 1134782 CDS YP_006772791.1 410480060 13696112 complement(4367..4744) 1 NC_018654.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); UV protection protein 4744 13696112 O3M_26167 Escherichia coli O104:H4 str. 2009EL-2050 UV protection protein YP_006772791.1 4367 R 1134782 CDS YP_006772792.1 410480061 13696113 4831..5442 1 NC_018654.1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; resolvase 5442 13696113 O3M_26172 Escherichia coli O104:H4 str. 2009EL-2050 resolvase YP_006772792.1 4831 D 1134782 CDS YP_006772793.1 410480062 13696114 5941..6144 1 NC_018654.1 hypothetical protein 6144 13696114 O3M_26177 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772793.1 5941 D 1134782 CDS YP_006772794.1 410480063 13696115 6279..7037 1 NC_018654.1 COG3121 P pilus assembly protein, chaperone PapD; Chaperone protein Agg3D 7037 13696115 O3M_26182 Escherichia coli O104:H4 str. 2009EL-2050 Chaperone protein Agg3D YP_006772794.1 6279 D 1134782 CDS YP_006772795.1 410480064 13696116 7195..9579 1 NC_018654.1 COG3188 P pilus assembly protein, porin PapC; Outer membrane usher protein Agg3C 9579 13696116 O3M_26187 Escherichia coli O104:H4 str. 2009EL-2050 Outer membrane usher protein Agg3C YP_006772795.1 7195 D 1134782 CDS YP_006772796.1 410480065 13696117 9593..10030 1 NC_018654.1 Protein Agg3B, putative invasin 10030 13696117 O3M_26192 Escherichia coli O104:H4 str. 2009EL-2050 Protein Agg3B, putative invasin YP_006772796.1 9593 D 1134782 CDS YP_006772797.1 410480066 13696118 10132..10635 1 NC_018654.1 hypothetical protein 10635 13696118 O3M_26197 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772797.1 10132 D 1134782 CDS YP_006772798.1 410480067 13696119 10772..11092 1 NC_018654.1 COG4584 Transposase and inactivated derivatives; transposase 11092 13696119 O3M_26202 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772798.1 10772 D 1134782 CDS YP_006772799.1 410480068 13696120 complement(11061..11222) 1 NC_018654.1 COG3464 Transposase and inactivated derivatives; hypothetical protein 11222 13696120 O3M_26207 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772799.1 11061 R 1134782 CDS YP_006772800.1 410480069 13696121 11408..11809 1 NC_018654.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 11809 13696121 O3M_26212 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772800.1 11408 D 1134782 CDS YP_006772801.1 410480070 13696122 11806..12153 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; transposase 12153 13696122 O3M_26217 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772801.1 11806 D 1134782 CDS YP_006772802.1 410480071 13696123 12203..12451 1 NC_018654.1 COG2202 FOG: PAS/PAC domain; hypothetical protein 12451 13696123 O3M_26222 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772802.1 12203 D 1134782 CDS YP_006772803.1 410480072 13696124 12453..13742 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; protein encoded within IS 13742 13696124 O3M_26227 Escherichia coli O104:H4 str. 2009EL-2050 protein encoded within IS YP_006772803.1 12453 D 1134782 CDS YP_006772804.1 410480073 13696125 complement(13776..14033) 1 NC_018654.1 COG2801 Transposase and inactivated derivatives; ISEhe3 orfB 14033 13696125 O3M_26232 Escherichia coli O104:H4 str. 2009EL-2050 ISEhe3 orfB YP_006772804.1 13776 R 1134782 CDS YP_006772805.1 410480074 13696126 14078..14302 1 NC_018654.1 COG2801 Transposase and inactivated derivatives; hypothetical protein 14302 13696126 O3M_26237 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772805.1 14078 D 1134782 CDS YP_006772806.1 410480075 13696127 complement(14327..14515) 1 NC_018654.1 COG2801 Transposase and inactivated derivatives; IS150 ORF B; transposase 14515 13696127 O3M_26242 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772806.1 14327 R 1134782 CDS YP_006772807.1 410480076 13696128 complement(14758..15258) 1 NC_018654.1 COG2963 Transposase and inactivated derivatives; ISRSO11-transposase orfA protein 15258 13696128 O3M_26247 Escherichia coli O104:H4 str. 2009EL-2050 ISRSO11-transposase orfA protein YP_006772807.1 14758 R 1134782 CDS YP_006772808.1 410480077 13696129 15694..16722 1 NC_018654.1 hypothetical protein 16722 13696129 O3M_26257 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772808.1 15694 D 1134782 CDS YP_006772809.1 410480078 13696130 16745..16969 1 NC_018654.1 hypothetical protein 16969 13696130 O3M_26262 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772809.1 16745 D 1134782 CDS YP_006772810.1 410480079 13696131 16978..17265 1 NC_018654.1 IPP isomerase: Isopentenyl pyrophosphate isomerase; IPP:DMAPP isomerase; COG1443 Isopentenyldiphosphate isomerase; isopentenyl-diphosphate delta-isomerase 17265 13696131 O3M_26267 Escherichia coli O104:H4 str. 2009EL-2050 isopentenyl-diphosphate delta-isomerase YP_006772810.1 16978 D 1134782 CDS YP_006772811.1 410480080 13696132 complement(17768..17920) 1 NC_018654.1 hypothetical protein 17920 13696132 O3M_26272 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772811.1 17768 R 1134782 CDS YP_006772812.1 410480081 13696133 complement(17920..18081) 1 NC_018654.1 hypothetical protein 18081 13696133 O3M_26277 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772812.1 17920 R 1134782 CDS YP_006772813.1 410480082 13696134 18080..19060 1 NC_018654.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 19060 13696134 O3M_26282 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772813.1 18080 D 1134782 CDS YP_006772814.1 410480083 13696135 19422..20246 1 NC_018654.1 COG3547 Transposase and inactivated derivatives; transposase 20246 13696135 O3M_26287 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772814.1 19422 D 1134782 CDS YP_006772815.1 410480084 13696136 complement(20489..20743) 1 NC_018654.1 COG2963 Transposase and inactivated derivatives; IS1; transposase ORF A, IS1 20743 13696136 O3M_26292 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS1 YP_006772815.1 20489 R 1134782 CDS YP_006772816.1 410480085 13696137 complement(20994..21791) 1 NC_018654.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional activator aggR (AAF-III) regulatory protein 21791 13696137 O3M_26297 Escherichia coli O104:H4 str. 2009EL-2050 transcriptional activator aggR (AAF-III) regulatory protein YP_006772816.1 20994 R 1134782 CDS YP_006772817.1 410480086 13696138 22525..22851 1 NC_018654.1 COG2963 Transposase and inactivated derivatives; IS629, IS3 family protein; transposase ORF A, IS629, IS3 family protein 22851 13696138 O3M_26307 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF A, IS629, IS3 family protein YP_006772817.1 22525 D 1134782 CDS YP_006772818.1 410480087 13696139 22848..23237 1 NC_018654.1 COG2801 Transposase and inactivated derivatives; IS629 transposase OrfB 23237 13696139 O3M_26312 Escherichia coli O104:H4 str. 2009EL-2050 IS629 transposase OrfB YP_006772818.1 22848 D 1134782 CDS YP_006772819.1 410480088 13696140 23140..23307 1 NC_018654.1 COG2801 Transposase and inactivated derivatives; transposase 23307 13696140 O3M_26317 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772819.1 23140 D 1134782 CDS YP_006772820.1 410480089 13696141 23929..25452 1 NC_018654.1 CP4-6 prophage (modular protein); COG3344 Retron-type reverse transcriptase; reverse transcriptase-like protein 25452 13696141 O3M_26322 Escherichia coli O104:H4 str. 2009EL-2050 reverse transcriptase-like protein YP_006772820.1 23929 D 1134782 CDS YP_006772821.1 410480090 13696142 complement(26793..26927) 1 NC_018654.1 hypothetical protein 26927 13696142 O3M_26337 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772821.1 26793 R 1134782 CDS YP_006772822.1 410480091 13696143 26926..27906 1 NC_018654.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 27906 13696143 O3M_26342 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772822.1 26926 D 1134782 CDS YP_006772823.1 410480092 13696144 28499..28699 1 NC_018654.1 hypothetical protein 28699 13696144 O3M_26352 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772823.1 28499 D 1134782 CDS YP_006772824.1 410480093 13696146 complement(31987..32223) 1 NC_018654.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 32223 13696146 O3M_26377 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772824.1 31987 R 1134782 CDS YP_006772825.1 410480094 13696147 32994..34124 1 NC_018654.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; AatP permease 34124 13696147 O3M_26387 Escherichia coli O104:H4 str. 2009EL-2050 AatP permease YP_006772825.1 32994 D 1134782 CDS YP_006772826.1 410480095 13696148 34121..35359 1 NC_018654.1 outer membrane protein AatA 35359 13696148 O3M_26392 Escherichia coli O104:H4 str. 2009EL-2050 outer membrane protein AatA YP_006772826.1 34121 D 1134782 CDS YP_006772827.1 410480096 13696149 35439..36077 1 NC_018654.1 AatB protein 36077 13696149 O3M_26397 Escherichia coli O104:H4 str. 2009EL-2050 AatB protein YP_006772827.1 35439 D 1134782 CDS YP_006772828.1 410480097 13696063 36070..36699 1 NC_018654.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein AatC 36699 13696063 O3M_26402 Escherichia coli O104:H4 str. 2009EL-2050 ABC transporter ATP-binding protein AatC YP_006772828.1 36070 D 1134782 CDS YP_006772829.1 410480098 13696064 36779..37927 1 NC_018654.1 COG0815 Apolipoprotein N-acyltransferase; AatD 37927 13696064 O3M_26407 Escherichia coli O104:H4 str. 2009EL-2050 AatD YP_006772829.1 36779 D 1134782 CDS YP_006772830.1 410480099 13696065 38902..40035 1 NC_018654.1 COG3547 Transposase and inactivated derivatives; transposase, IS110 family protein 40035 13696065 O3M_26412 Escherichia coli O104:H4 str. 2009EL-2050 transposase, IS110 family protein YP_006772830.1 38902 D 1134782 CDS YP_006772831.1 410480100 13696066 complement(40145..41713) 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; IS66 family protein; transposase ORF1, IS66 family protein 41713 13696066 O3M_26417 Escherichia coli O104:H4 str. 2009EL-2050 transposase ORF1, IS66 family protein YP_006772831.1 40145 R 1134782 CDS YP_006772832.1 410480101 13696067 complement(41755..42093) 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; IS66 transposase 42093 13696067 O3M_26422 Escherichia coli O104:H4 str. 2009EL-2050 IS66 transposase YP_006772832.1 41755 R 1134782 CDS YP_006772833.1 410480102 13696068 complement(42090..42524) 1 NC_018654.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 42524 13696068 O3M_26427 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772833.1 42090 R 1134782 CDS YP_006772834.1 410480103 13696069 42638..42823 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 42823 13696069 O3M_26432 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772834.1 42638 D 1134782 CDS YP_006772835.1 410480104 13696070 complement(43118..47212) 1 NC_018654.1 COG3468 Type V secretory pathway, adhesin AidA; protease IgA1 47212 13696070 O3M_26437 Escherichia coli O104:H4 str. 2009EL-2050 protease IgA1 YP_006772835.1 43118 R 1134782 CDS YP_006772836.1 410480105 13696071 complement(47734..47991) 1 NC_018654.1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; recombinase 47991 13696071 O3M_26442 Escherichia coli O104:H4 str. 2009EL-2050 recombinase YP_006772836.1 47734 R 1134782 CDS YP_006772837.1 410480106 13696072 48786..49586 1 NC_018654.1 YubP 49586 13696072 O3M_26447 Escherichia coli O104:H4 str. 2009EL-2050 YubP YP_006772837.1 48786 D 1134782 CDS YP_006772838.1 410480107 13696073 complement(49904..50413) 1 NC_018654.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic transglycosylase 50413 13696073 O3M_26452 Escherichia coli O104:H4 str. 2009EL-2050 lytic transglycosylase YP_006772838.1 49904 R 1134782 CDS YP_006772839.1 410480108 13696074 50837..51220 1 NC_018654.1 COG1082 Sugar phosphate isomerases/epimerases; conjugal transfer protein TraM 51220 13696074 O3M_26457 Escherichia coli O104:H4 str. 2009EL-2050 conjugal transfer protein TraM YP_006772839.1 50837 D 1134782 CDS YP_006772840.1 410480109 13696075 complement(51878..52144) 1 NC_018654.1 COG1662 Transposase and inactivated derivatives, IS1 family; IS1 transposase 52144 13696075 O3M_26462 Escherichia coli O104:H4 str. 2009EL-2050 IS1 transposase YP_006772840.1 51878 R 1134782 CDS YP_006772841.1 410480110 13696076 complement(52289..52564) 1 NC_018654.1 COG3677 Transposase and inactivated derivatives; IS1 repressor protein InsA 52564 13696076 O3M_26467 Escherichia coli O104:H4 str. 2009EL-2050 IS1 repressor protein InsA YP_006772841.1 52289 R 1134782 CDS YP_006772842.1 410480111 13696077 52686..53360 1 NC_018654.1 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; conjugal transfer nickase/helicase TraI 53360 13696077 O3M_26472 Escherichia coli O104:H4 str. 2009EL-2050 conjugal transfer nickase/helicase TraI YP_006772842.1 52686 D 1134782 CDS YP_006772843.1 410480112 13696078 53365..57078 1 NC_018654.1 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; conjugal transfer nickase/helicase TraI 57078 13696078 O3M_26477 Escherichia coli O104:H4 str. 2009EL-2050 conjugal transfer nickase/helicase TraI YP_006772843.1 53365 D 1134782 CDS YP_006772844.1 410480113 13696079 57154..57291 1 NC_018654.1 conjugal transfer nickase/helicase TraI 57291 13696079 O3M_26482 Escherichia coli O104:H4 str. 2009EL-2050 conjugal transfer nickase/helicase TraI YP_006772844.1 57154 D 1134782 CDS YP_006772845.1 410480114 13696080 57311..58057 1 NC_018654.1 conjugal transfer pilus acetylation protein TraX 58057 13696080 O3M_26487 Escherichia coli O104:H4 str. 2009EL-2050 conjugal transfer pilus acetylation protein TraX YP_006772845.1 57311 D 1134782 CDS YP_006772846.1 410480115 13696081 58112..58672 1 NC_018654.1 conjugal transfer fertility inhibition protein FinO 58672 13696081 O3M_26492 Escherichia coli O104:H4 str. 2009EL-2050 conjugal transfer fertility inhibition protein FinO YP_006772846.1 58112 D 1134782 CDS YP_006772847.1 410480116 13696082 58901..59335 1 NC_018654.1 COG2963 Transposase and inactivated derivatives; hypothetical protein 59335 13696082 O3M_26497 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772847.1 58901 D 1134782 CDS YP_006772848.1 410480117 13696083 59332..59628 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 59628 13696083 O3M_26502 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772848.1 59332 D 1134782 CDS YP_006772849.1 410480118 13696084 59702..59887 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; transposase 59887 13696084 O3M_26507 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772849.1 59702 D 1134782 CDS YP_006772850.1 410480119 13696085 complement(59941..61512) 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 61512 13696085 O3M_26512 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772850.1 59941 R 1134782 CDS YP_006772851.1 410480120 13696086 complement(61532..61879) 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; IS66 family element, orf2 61879 13696086 O3M_26517 Escherichia coli O104:H4 str. 2009EL-2050 IS66 family element, orf2 YP_006772851.1 61532 R 1134782 CDS YP_006772852.1 410480121 13696087 complement(61879..62556) 1 NC_018654.1 COG4584 Transposase and inactivated derivatives; IS66 family transposase orfA 62556 13696087 O3M_26522 Escherichia coli O104:H4 str. 2009EL-2050 IS66 family transposase orfA YP_006772852.1 61879 R 1134782 CDS YP_006772853.1 410480122 13696088 62706..62876 1 NC_018654.1 hypothetical protein 62876 13696088 O3M_26527 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772853.1 62706 D 1134782 CDS YP_006772854.1 410480123 13696089 complement(63284..64264) 1 NC_018654.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 64264 13696089 O3M_26532 Escherichia coli O104:H4 str. 2009EL-2050 transposase YP_006772854.1 63284 R 1134782 CDS YP_006772855.1 410480124 13696090 64545..64799 1 NC_018654.1 replication protein 64799 13696090 O3M_26537 Escherichia coli O104:H4 str. 2009EL-2050 replication protein YP_006772855.1 64545 D 1134782 CDS YP_006772856.1 410480125 13696091 65037..65111 1 NC_018654.1 leader peptide RepL 65111 13696091 O3M_26542 Escherichia coli O104:H4 str. 2009EL-2050 leader peptide RepL YP_006772856.1 65037 D 1134782 CDS YP_006772857.1 410480126 13696092 65104..65292 1 NC_018654.1 replication protein 65292 13696092 O3M_26547 Escherichia coli O104:H4 str. 2009EL-2050 replication protein YP_006772857.1 65104 D 1134782 CDS YP_006772858.1 410480127 13696093 65261..65932 1 NC_018654.1 replication protein 65932 13696093 O3M_26552 Escherichia coli O104:H4 str. 2009EL-2050 replication protein YP_006772858.1 65261 D 1134782 CDS YP_006772859.1 410480128 13696094 66840..67124 1 NC_018654.1 hypothetical protein 67124 13696094 O3M_26557 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772859.1 66840 D 1134782 CDS YP_006772860.1 410480129 13696095 67124..67399 1 NC_018654.1 COG3668 Plasmid stabilization system protein; hypothetical protein 67399 13696095 O3M_26562 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772860.1 67124 D 1134782 CDS YP_006772861.1 410480130 13696096 67405..67650 1 NC_018654.1 COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain; hypothetical protein 67650 13696096 O3M_26567 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772861.1 67405 D 1134782 CDS YP_006772862.1 410480131 13696097 67852..68013 1 NC_018654.1 COG3668 Plasmid stabilization system protein; hypothetical protein 68013 13696097 O3M_26572 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772862.1 67852 D 1134782 CDS YP_006772863.1 410480132 13696098 68382..69122 1 NC_018654.1 COG0582 Integrase; resolvase (protein D) 69122 13696098 O3M_26577 Escherichia coli O104:H4 str. 2009EL-2050 resolvase (protein D) YP_006772863.1 68382 D 1134782 CDS YP_006772864.1 410480133 13696099 complement(69401..70378) 1 NC_018654.1 RepFIB replication protein A 70378 13696099 O3M_26582 Escherichia coli O104:H4 str. 2009EL-2050 RepFIB replication protein A YP_006772864.1 69401 R 1134782 CDS YP_006772865.1 410480134 13696100 71464..71619 1 NC_018654.1 COG3436 Transposase and inactivated derivatives; hypothetical protein 71619 13696100 O3M_26587 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772865.1 71464 D 1134782 CDS YP_006772866.1 410480135 13696101 complement(71702..72130) 1 NC_018654.1 COG1487 Predicted nucleic acid-binding protein, contains PIN domain; hypothetical protein 72130 13696101 O3M_26592 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772866.1 71702 R 1134782 CDS YP_006772867.1 410480136 13696102 complement(72127..72357) 1 NC_018654.1 COG4456 Virulence-associated protein and related proteins; hypothetical protein 72357 13696102 O3M_26597 Escherichia coli O104:H4 str. 2009EL-2050 hypothetical protein YP_006772867.1 72127 R 1134782 CDS YP_006772868.1 410480137 13696103 72952..73170 1 NC_018654.1 COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid; plasmid maintenance protein CcdA 73170 13696103 O3M_26602 Escherichia coli O104:H4 str. 2009EL-2050 plasmid maintenance protein CcdA YP_006772868.1 72952 D 1134782 CDS YP_006772869.1 410480138 13696104 73172..73477 1 NC_018654.1 plasmid maintenance protein CcdB 73477 13696104 O3M_26607 Escherichia coli O104:H4 str. 2009EL-2050 plasmid maintenance protein CcdB YP_006772869.1 73172 D 1134782 CDS