-- dump date 20140619_082633 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001728984.1 170079664 6058969 190..255 1 NC_010473.1 involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 255 thrL 6058969 thrL Escherichia coli str. K-12 substr. DH10B thr operon leader peptide YP_001728984.1 190 D 316385 CDS YP_001728985.1 170079665 6058347 337..2799 1 NC_010473.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2799 thrA 6058347 thrA Escherichia coli str. K-12 substr. DH10B bifunctional aspartokinase I/homoserine dehydrogenase I YP_001728985.1 337 D 316385 CDS YP_001728986.1 170079666 6058639 2801..3733 1 NC_010473.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3733 thrB 6058639 thrB Escherichia coli str. K-12 substr. DH10B homoserine kinase YP_001728986.1 2801 D 316385 CDS YP_001728987.1 170079667 6062260 3734..5020 1 NC_010473.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5020 thrC 6062260 thrC Escherichia coli str. K-12 substr. DH10B threonine synthase YP_001728987.1 3734 D 316385 CDS YP_001728988.1 170079668 6061721 5234..5530 1 NC_010473.1 hypothetical protein 5530 yaaX 6061721 yaaX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001728988.1 5234 D 316385 CDS YP_001728989.1 170079669 6061859 complement(5683..6459) 1 NC_010473.1 hypothetical protein 6459 yaaA 6061859 yaaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001728989.1 5683 R 316385 CDS YP_001728990.1 170079670 6061809 complement(6529..7959) 1 NC_010473.1 transporter 7959 yaaJ 6061809 yaaJ Escherichia coli str. K-12 substr. DH10B transporter YP_001728990.1 6529 R 316385 CDS YP_001728991.1 170079671 6061856 8238..9191 1 NC_010473.1 transaldolase B 9191 talB 6061856 talB Escherichia coli str. K-12 substr. DH10B transaldolase B YP_001728991.1 8238 D 316385 CDS YP_001728992.1 170079672 6061839 9306..9893 1 NC_010473.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9893 mogA 6061839 mogA Escherichia coli str. K-12 substr. DH10B molybdenum cofactor biosynthesis protein MogA YP_001728992.1 9306 D 316385 CDS YP_001728993.1 170079673 6060849 complement(9928..10494) 1 NC_010473.1 hypothetical protein 10494 yaaH 6060849 yaaH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001728993.1 9928 R 316385 CDS YP_001728994.1 170079674 6060848 complement(10643..11356) 1 NC_010473.1 hypothetical protein 11356 yaaW 6060848 yaaW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001728994.1 10643 R 316385 CDS YP_001728995.1 170079675 6061775 10830..11315 1 NC_010473.1 hypothetical protein 11315 htgA 6061775 htgA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001728995.1 10830 D 316385 CDS YP_001728996.1 170079676 6061719 complement(11382..11786) 1 NC_010473.1 hypothetical protein 11786 yaaI 6061719 yaaI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001728996.1 11382 R 316385 CDS YP_001728997.1 170079677 6060570 12163..14079 1 NC_010473.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14079 dnaK 6060570 dnaK Escherichia coli str. K-12 substr. DH10B molecular chaperone DnaK YP_001728997.1 12163 D 316385 CDS YP_001728998.1 170079678 6060564 14168..15298 1 NC_010473.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 15298 dnaJ 6060564 dnaJ Escherichia coli str. K-12 substr. DH10B chaperone protein DnaJ YP_001728998.1 14168 D 316385 CDS YP_001728999.1 170079679 6061805 15445..16557 1 NC_010473.1 IS186/IS421 transposase 16557 insL-1 6061805 insL-1 Escherichia coli str. K-12 substr. DH10B IS186/IS421 transposase YP_001728999.1 15445 D 316385 CDS YP_001729000.1 170079680 6061760 complement(16751..16960) 1 NC_010473.1 regulatory protein for HokC, overlaps CDS of hokC 16960 mokC 6061760 mokC Escherichia coli str. K-12 substr. DH10B regulatory protein for HokC, overlaps CDS of hokC YP_001729000.1 16751 R 316385 CDS YP_001729001.1 170079681 6061702 complement(16751..16903) 1 NC_010473.1 toxic membrane protein, small 16903 hokC 6061702 hokC Escherichia coli str. K-12 substr. DH10B toxic membrane protein, small YP_001729001.1 16751 R 316385 CDS YP_001729002.1 170079682 6059585 17489..18655 1 NC_010473.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 18655 nhaA 6059585 nhaA Escherichia coli str. K-12 substr. DH10B pH-dependent sodium/proton antiporter YP_001729002.1 17489 D 316385 CDS YP_001729003.1 170079683 6060870 18715..19620 1 NC_010473.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 19620 nhaR 6060870 nhaR Escherichia coli str. K-12 substr. DH10B transcriptional activator NhaR YP_001729003.1 18715 D 316385 CDS YP_001729004.1 170079684 6060829 complement(19811..20314) 1 NC_010473.1 IS1 transposase InsAB' 20314 insB-1 6060829 insB-1 Escherichia coli str. K-12 substr. DH10B IS1 transposase InsAB' YP_001729004.1 19811 R 316385 CDS YP_001729005.1 170079685 6061774 complement(20233..20508) 1 NC_010473.1 IS1 repressor protein InsA 20508 insA-1 6061774 insA-1 Escherichia coli str. K-12 substr. DH10B IS1 repressor protein InsA YP_001729005.1 20233 R 316385 CDS YP_001729006.1 170079686 6061729 complement(20815..21078) 1 NC_010473.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 21078 rpsT 6061729 rpsT Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S20 YP_001729006.1 20815 R 316385 CDS YP_001729007.1 170079687 6061762 21181..21399 1 NC_010473.1 hypothetical protein 21399 yaaY 6061762 yaaY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729007.1 21181 D 316385 CDS YP_001729008.1 170079688 6060863 21407..22348 1 NC_010473.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 22348 ribF 6060863 ribF Escherichia coli str. K-12 substr. DH10B bifunctional riboflavin kinase/FMN adenylyltransferase YP_001729008.1 21407 D 316385 CDS YP_001729009.1 170079689 6060861 22391..25207 1 NC_010473.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 25207 ileS 6060861 ileS Escherichia coli str. K-12 substr. DH10B isoleucyl-tRNA synthetase YP_001729009.1 22391 D 316385 CDS YP_001729010.1 170079690 6060712 25207..25701 1 NC_010473.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 25701 lspA 6060712 lspA Escherichia coli str. K-12 substr. DH10B lipoprotein signal peptidase YP_001729010.1 25207 D 316385 CDS YP_001729011.1 170079691 6061711 25826..26275 1 NC_010473.1 FKBP-type peptidyl-prolyl cis-trans isomerase 26275 fkpB 6061711 fkpB Escherichia coli str. K-12 substr. DH10B FKBP-type peptidyl-prolyl cis-trans isomerase YP_001729011.1 25826 D 316385 CDS YP_001729012.1 170079692 6061757 26277..27227 1 NC_010473.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 27227 ispH 6061757 ispH Escherichia coli str. K-12 substr. DH10B 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001729012.1 26277 D 316385 CDS YP_001729013.1 170079693 6061670 27293..28207 1 NC_010473.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 28207 rihC 6061670 rihC Escherichia coli str. K-12 substr. DH10B ribonucleoside hydrolase RihC YP_001729013.1 27293 D 316385 CDS YP_001729014.1 170079694 6061749 28374..29195 1 NC_010473.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 29195 dapB 6061749 dapB Escherichia coli str. K-12 substr. DH10B dihydrodipicolinate reductase YP_001729014.1 28374 D 316385 CDS YP_001729015.1 170079695 6061743 29651..30799 1 NC_010473.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 30799 carA 6061743 carA Escherichia coli str. K-12 substr. DH10B carbamoyl phosphate synthase small subunit YP_001729015.1 29651 D 316385 CDS YP_001729016.1 170079696 6061731 30817..34038 1 NC_010473.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 34038 carB 6061731 carB Escherichia coli str. K-12 substr. DH10B carbamoyl phosphate synthase large subunit YP_001729016.1 30817 D 316385 CDS YP_001729017.1 170079697 6060689 34300..34695 1 NC_010473.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 34695 caiF 6060689 caiF Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator CaiF YP_001729017.1 34300 D 316385 CDS YP_001729018.1 170079698 6060753 complement(34781..35371) 1 NC_010473.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 35371 caiE 6060753 caiE Escherichia coli str. K-12 substr. DH10B carnitine operon protein CaiE YP_001729018.1 34781 R 316385 CDS YP_001729019.2 228937031 6061640 complement(35377..36162) 1 NC_010473.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 36162 caiD 6061640 caiD Escherichia coli str. K-12 substr. DH10B carnitinyl-CoA dehydratase YP_001729019.2 35377 R 316385 CDS YP_001729020.1 170079700 6061718 complement(36271..37839) 1 NC_010473.1 putative crotonobetaine/carnitine-CoA ligase 37839 caiC 6061718 caiC Escherichia coli str. K-12 substr. DH10B putative crotonobetaine/carnitine-CoA ligase YP_001729020.1 36271 R 316385 CDS YP_001729021.1 170079701 6060847 complement(37898..39115) 1 NC_010473.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 39115 caiB 6060847 caiB Escherichia coli str. K-12 substr. DH10B crotonobetainyl-CoA:carnitine CoA-transferase YP_001729021.1 37898 R 316385 CDS YP_001729022.1 170079702 6061674 complement(39244..40386) 1 NC_010473.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 40386 caiA 6061674 caiA Escherichia coli str. K-12 substr. DH10B crotonobetainyl-CoA dehydrogenase YP_001729022.1 39244 R 316385 CDS YP_001729023.1 170079703 6061707 complement(40417..41931) 1 NC_010473.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 41931 caiT 6061707 caiT Escherichia coli str. K-12 substr. DH10B L-carnitine/gamma-butyrobetaine antiporter YP_001729023.1 40417 R 316385 CDS YP_001729024.1 170079704 6060840 42403..43173 1 NC_010473.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA 43173 fixA 6060840 fixA Escherichia coli str. K-12 substr. DH10B putative electron transfer flavoprotein FixA YP_001729024.1 42403 D 316385 CDS YP_001729025.1 170079705 6061693 43188..44129 1 NC_010473.1 involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB 44129 fixB 6061693 fixB Escherichia coli str. K-12 substr. DH10B putative electron transfer flavoprotein FixB YP_001729025.1 43188 D 316385 CDS YP_001729026.1 170079706 6060832 44180..45466 1 NC_010473.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC 45466 fixC 6060832 fixC Escherichia coli str. K-12 substr. DH10B putative oxidoreductase FixC YP_001729026.1 44180 D 316385 CDS YP_001729027.1 170079707 6060834 45463..45750 1 NC_010473.1 4Fe-4S ferredoxin 45750 fixX 6060834 fixX Escherichia coli str. K-12 substr. DH10B 4Fe-4S ferredoxin YP_001729027.1 45463 D 316385 CDS YP_001729028.1 170079708 6061685 45807..47138 1 NC_010473.1 transporter 47138 yaaU 6061685 yaaU Escherichia coli str. K-12 substr. DH10B transporter YP_001729028.1 45807 D 316385 CDS YP_001729029.1 170079709 6061681 47246..47776 1 NC_010473.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 47776 kefF 6061681 kefF Escherichia coli str. K-12 substr. DH10B glutathione-regulated potassium-efflux system ancillary protein KefF YP_001729029.1 47246 D 316385 CDS YP_001729030.1 170079710 6061581 47769..49631 1 NC_010473.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 49631 kefC 6061581 kefC Escherichia coli str. K-12 substr. DH10B glutathione-regulated potassium-efflux system protein KefC YP_001729030.1 47769 D 316385 CDS YP_001729031.1 170079711 6061666 49823..50302 1 NC_010473.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 50302 folA 6061666 folA Escherichia coli str. K-12 substr. DH10B dihydrofolate reductase YP_001729031.1 49823 D 316385 CDS YP_001729032.1 170079712 6060780 complement(50380..51222) 1 NC_010473.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 51222 apaH 6060780 apaH Escherichia coli str. K-12 substr. DH10B diadenosine tetraphosphatase YP_001729032.1 50380 R 316385 CDS YP_001729033.1 170079713 6060560 complement(51229..51606) 1 NC_010473.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 51606 apaG 6060560 apaG Escherichia coli str. K-12 substr. DH10B ApaG protein YP_001729033.1 51229 R 316385 CDS YP_001729034.1 170079714 6061655 complement(51609..52430) 1 NC_010473.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 52430 ksgA 6061655 ksgA Escherichia coli str. K-12 substr. DH10B dimethyladenosine transferase YP_001729034.1 51609 R 316385 CDS YP_001729035.1 170079715 6061608 complement(52427..53416) 1 NC_010473.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 53416 pdxA 6061608 pdxA Escherichia coli str. K-12 substr. DH10B 4-hydroxythreonine-4-phosphate dehydrogenase YP_001729035.1 52427 R 316385 CDS YP_001729036.1 170079716 6061611 complement(53416..54702) 1 NC_010473.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 54702 surA 6061611 surA Escherichia coli str. K-12 substr. DH10B peptidyl-prolyl cis-trans isomerase SurA YP_001729036.1 53416 R 316385 CDS YP_001729037.1 170079717 6061599 complement(54755..57109) 1 NC_010473.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 57109 imp 6061599 imp Escherichia coli str. K-12 substr. DH10B organic solvent tolerance protein YP_001729037.1 54755 R 316385 CDS YP_001729038.1 170079718 6061527 57364..58179 1 NC_010473.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 58179 djlA 6061527 djlA Escherichia coli str. K-12 substr. DH10B Dna-J like membrane chaperone protein YP_001729038.1 57364 D 316385 CDS YP_001729039.1 170079719 6058505 complement(59687..60346) 1 NC_010473.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 60346 rluA 6058505 rluA Escherichia coli str. K-12 substr. DH10B 23S rRNA/tRNA pseudouridine synthase A YP_001729039.1 59687 R 316385 CDS YP_001729040.1 170079720 6060357 63738..64196 1 NC_010473.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 64196 mraZ 6060357 mraZ Escherichia coli str. K-12 substr. DH10B cell division protein MraZ YP_001729040.1 63738 D 316385 CDS YP_001729041.1 170079721 6061555 64198..65139 1 NC_010473.1 contains two mutations: synonymous changes in codons 113 and 114; S-adenosyl-methyltransferase MraW 65139 mraW 6061555 mraW Escherichia coli str. K-12 substr. DH10B S-adenosyl-methyltransferase MraW YP_001729041.1 64198 D 316385 CDS YP_001729042.1 170079722 6060757 65136..65501 1 NC_010473.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 65501 ftsL 6060757 ftsL Escherichia coli str. K-12 substr. DH10B cell division protein FtsL YP_001729042.1 65136 D 316385 CDS YP_001729043.1 170079723 6061496 65517..67283 1 NC_010473.1 contains eleven mutations: synonymous changes in codons 164, 168, 170, 179, 228, 250, 305, 314, 425, 466, and 477; transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) 67283 ftsI 6061496 ftsI Escherichia coli str. K-12 substr. DH10B transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) YP_001729043.1 65517 D 316385 CDS YP_001729044.1 170079724 6061495 67270..68757 1 NC_010473.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 68757 murE 6061495 murE Escherichia coli str. K-12 substr. DH10B UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001729044.1 67270 D 316385 CDS YP_001729045.1 170079725 6061602 68754..70112 1 NC_010473.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 70112 murF 6061602 murF Escherichia coli str. K-12 substr. DH10B UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_001729045.1 68754 D 316385 CDS YP_001729046.1 170079726 6061592 70106..71188 1 NC_010473.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 71188 mraY 6061592 mraY Escherichia coli str. K-12 substr. DH10B phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001729046.1 70106 D 316385 CDS YP_001729047.1 170079727 6061589 71191..72507 1 NC_010473.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 72507 murD 6061589 murD Escherichia coli str. K-12 substr. DH10B UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001729047.1 71191 D 316385 CDS YP_001729048.1 170079728 6062336 72507..73751 1 NC_010473.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 73751 ftsW 6062336 ftsW Escherichia coli str. K-12 substr. DH10B cell division protein FtsW YP_001729048.1 72507 D 316385 CDS YP_001729049.1 170079729 6061471 73748..74815 1 NC_010473.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 74815 murG 6061471 murG Escherichia coli str. K-12 substr. DH10B undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001729049.1 73748 D 316385 CDS YP_001729050.1 170079730 6061468 74869..76344 1 NC_010473.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 76344 murC 6061468 murC Escherichia coli str. K-12 substr. DH10B UDP-N-acetylmuramate--L-alanine ligase YP_001729050.1 74869 D 316385 CDS YP_001729051.1 170079731 6061511 76337..77257 1 NC_010473.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 77257 ddl 6061511 ddl Escherichia coli str. K-12 substr. DH10B D-alanine--D-alanine ligase YP_001729051.1 76337 D 316385 CDS YP_001729052.1 170079732 6061565 77259..78089 1 NC_010473.1 involved in septum formation; cell division protein FtsQ 78089 ftsQ 6061565 ftsQ Escherichia coli str. K-12 substr. DH10B cell division protein FtsQ YP_001729052.1 77259 D 316385 CDS YP_001729053.1 170079733 6061506 78086..79348 1 NC_010473.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 79348 ftsA 6061506 ftsA Escherichia coli str. K-12 substr. DH10B cell division protein FtsA YP_001729053.1 78086 D 316385 CDS YP_001729054.1 170079734 6061490 79409..80560 1 NC_010473.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 80560 ftsZ 6061490 ftsZ Escherichia coli str. K-12 substr. DH10B cell division protein FtsZ YP_001729054.1 79409 D 316385 CDS YP_001729055.1 170079735 6061533 80661..81578 1 NC_010473.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 81578 lpxC 6061533 lpxC Escherichia coli str. K-12 substr. DH10B UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001729055.1 80661 D 316385 CDS YP_001729056.1 170079736 6061485 81809..82321 1 NC_010473.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 82321 secM 6061485 secM Escherichia coli str. K-12 substr. DH10B SecA regulator SecM YP_001729056.1 81809 D 316385 CDS YP_001729057.1 170079737 6060734 82383..85088 1 NC_010473.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 85088 secA 6060734 secA Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit SecA YP_001729057.1 82383 D 316385 CDS YP_001729058.1 170079738 6061521 85148..85537 1 NC_010473.1 nucleoside triphosphate pyrophosphohydrolase 85537 mutT 6061521 mutT Escherichia coli str. K-12 substr. DH10B nucleoside triphosphate pyrophosphohydrolase YP_001729058.1 85148 D 316385 CDS YP_001729059.1 170079739 6061455 complement(85753..85950) 1 NC_010473.1 zinc-binding protein 85950 yacG 6061455 yacG Escherichia coli str. K-12 substr. DH10B zinc-binding protein YP_001729059.1 85753 R 316385 CDS YP_001729060.1 170079740 6061452 complement(85960..86703) 1 NC_010473.1 hypothetical protein 86703 yacF 6061452 yacF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729060.1 85960 R 316385 CDS YP_001729061.1 170079741 6060659 complement(86703..87323) 1 NC_010473.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 87323 coaE 6060659 coaE Escherichia coli str. K-12 substr. DH10B dephospho-CoA kinase YP_001729061.1 86703 R 316385 CDS YP_001729062.1 170079742 6061504 87548..88591 1 NC_010473.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 88591 guaC 6061504 guaC Escherichia coli str. K-12 substr. DH10B guanosine 5'-monophosphate oxidoreductase YP_001729062.1 87548 D 316385 CDS YP_001729063.1 170079743 6061353 complement(88626..89828) 1 NC_010473.1 type IV pilin biogenesis protein 89828 hofC 6061353 hofC Escherichia coli str. K-12 substr. DH10B type IV pilin biogenesis protein YP_001729063.1 88626 R 316385 CDS YP_001729064.1 170079744 6061494 complement(89818..91203) 1 NC_010473.1 hypothetical protein 91203 hofB 6061494 hofB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729064.1 89818 R 316385 CDS YP_001729065.1 170079745 6062314 complement(91213..91653) 1 NC_010473.1 putative major pilin subunit 91653 ppdD 6062314 ppdD Escherichia coli str. K-12 substr. DH10B putative major pilin subunit YP_001729065.1 91213 R 316385 CDS YP_001729066.1 170079746 6061483 complement(91856..92749) 1 NC_010473.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 92749 nadC 6061483 nadC Escherichia coli str. K-12 substr. DH10B quinolinate phosphoribosyltransferase YP_001729066.1 91856 R 316385 CDS YP_001729067.1 170079747 6061477 92837..93388 1 NC_010473.1 N-acetyl-anhydromuranmyl-L-alanine amidase 93388 ampD 6061477 ampD Escherichia coli str. K-12 substr. DH10B N-acetyl-anhydromuranmyl-L-alanine amidase YP_001729067.1 92837 D 316385 CDS YP_001729068.1 170079748 6061475 93385..94239 1 NC_010473.1 involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE 94239 ampE 6061475 ampE Escherichia coli str. K-12 substr. DH10B regulatory protein AmpE YP_001729068.1 93385 D 316385 CDS YP_001729069.1 170079749 6061459 complement(94282..95655) 1 NC_010473.1 aromatic amino acid transporter 95655 aroP 6061459 aroP Escherichia coli str. K-12 substr. DH10B aromatic amino acid transporter YP_001729069.1 94282 R 316385 CDS YP_001729070.1 170079750 6060779 96196..96960 1 NC_010473.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 96960 pdhR 6060779 pdhR Escherichia coli str. K-12 substr. DH10B transcriptional regulator PdhR YP_001729070.1 96196 D 316385 CDS YP_001729071.1 170079751 6060775 97121..99784 1 NC_010473.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 99784 aceE 6060775 aceE Escherichia coli str. K-12 substr. DH10B pyruvate dehydrogenase subunit E1 YP_001729071.1 97121 D 316385 CDS YP_001729072.1 170079752 6061449 99799..101691 1 NC_010473.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 101691 aceF 6061449 aceF Escherichia coli str. K-12 substr. DH10B dihydrolipoamide acetyltransferase YP_001729072.1 99799 D 316385 CDS YP_001729073.1 170079753 6061443 102016..103440 1 NC_010473.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 103440 lpd 6061443 lpd Escherichia coli str. K-12 substr. DH10B dihydrolipoamide dehydrogenase YP_001729073.1 102016 D 316385 CDS YP_001729074.1 170079754 6061405 complement(103511..105364) 1 NC_010473.1 hypothetical protein 105364 yacH 6061405 yacH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729074.1 103511 R 316385 CDS YP_001729075.1 170079755 6061409 105719..108316 1 NC_010473.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 108316 acnB 6061409 acnB Escherichia coli str. K-12 substr. DH10B bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_001729075.1 105719 D 316385 CDS YP_001729076.1 170079756 6061436 108492..108854 1 NC_010473.1 hypothetical protein 108854 yacL 6061436 yacL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729076.1 108492 D 316385 CDS YP_001729077.1 170079757 6062345 complement(108892..109686) 1 NC_010473.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 109686 speD 6062345 speD Escherichia coli str. K-12 substr. DH10B S-adenosylmethionine decarboxylase YP_001729077.1 108892 R 316385 CDS YP_001729078.1 170079758 6061294 complement(109702..110568) 1 NC_010473.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 110568 speE 6061294 speE Escherichia coli str. K-12 substr. DH10B spermidine synthase YP_001729078.1 109702 R 316385 CDS YP_001729079.1 170079759 6060630 complement(110674..111021) 1 NC_010473.1 hypothetical protein 111021 yacC 6060630 yacC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729079.1 110674 R 316385 CDS YP_001729080.1 170079760 6060624 111187..112737 1 NC_010473.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 112737 cueO 6060624 cueO Escherichia coli str. K-12 substr. DH10B multicopper oxidase YP_001729080.1 111187 D 316385 CDS YP_001729081.1 170079761 6060544 complement(112939..115329) 1 NC_010473.1 glucose dehydrogenase 115329 gcd 6060544 gcd Escherichia coli str. K-12 substr. DH10B glucose dehydrogenase YP_001729081.1 112939 R 316385 CDS YP_001729082.1 170079762 6060535 115535..116071 1 NC_010473.1 hypoxanthine phosphoribosyltransferase 116071 hpt 6060535 hpt Escherichia coli str. K-12 substr. DH10B hypoxanthine phosphoribosyltransferase YP_001729082.1 115535 D 316385 CDS YP_001729083.1 170079763 6061219 complement(116112..116774) 1 NC_010473.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 116774 can 6061219 can Escherichia coli str. K-12 substr. DH10B carbonic anhydrase YP_001729083.1 116112 R 316385 CDS YP_001729084.1 170079764 6060761 116883..117809 1 NC_010473.1 ABC transporter ATP-binding protein 117809 yadG 6060761 yadG Escherichia coli str. K-12 substr. DH10B ABC transporter ATP-binding protein YP_001729084.1 116883 D 316385 CDS YP_001729085.1 170079765 6060762 117806..118576 1 NC_010473.1 ABC transporter membrane protein 118576 yadH 6060762 yadH Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001729085.1 117806 D 316385 CDS YP_001729086.1 170079766 6061403 118681..119121 1 NC_010473.1 PTS enzyme IIA 119121 yadI 6061403 yadI Escherichia coli str. K-12 substr. DH10B PTS enzyme IIA YP_001729086.1 118681 D 316385 CDS YP_001729087.1 170079767 6061401 119185..120414 1 NC_010473.1 polysaccharide deacetylase lipoprotein 120414 yadE 6061401 yadE Escherichia coli str. K-12 substr. DH10B polysaccharide deacetylase lipoprotein YP_001729087.1 119185 D 316385 CDS YP_001729088.1 170079768 6061400 complement(120418..120798) 1 NC_010473.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 120798 panD 6061400 panD Escherichia coli str. K-12 substr. DH10B aspartate alpha-decarboxylase YP_001729088.1 120418 R 316385 CDS YP_001729089.1 170079769 6061394 121072..121974 1 NC_010473.1 transposase 121974 yadD 6061394 yadD Escherichia coli str. K-12 substr. DH10B transposase YP_001729089.1 121072 D 316385 CDS YP_001729090.1 170079770 6061395 complement(122048..122899) 1 NC_010473.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 122899 panC 6061395 panC Escherichia coli str. K-12 substr. DH10B pantoate--beta-alanine ligase YP_001729090.1 122048 R 316385 CDS YP_001729091.1 170079771 6061341 complement(122911..123705) 1 NC_010473.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 123705 panB 6061341 panB Escherichia coli str. K-12 substr. DH10B 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001729091.1 122911 R 316385 CDS YP_001729092.1 170079772 6062319 complement(123819..125057) 1 NC_010473.1 putative fimbrial-like adhesin protein 125057 yadC 6062319 yadC Escherichia coli str. K-12 substr. DH10B putative fimbrial-like adhesin protein YP_001729092.1 123819 R 316385 CDS YP_001729093.1 170079773 6061375 complement(125107..125703) 1 NC_010473.1 fimbrial-like adhesin protein 125703 yadK 6061375 yadK Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729093.1 125107 R 316385 CDS YP_001729094.1 170079774 6060744 complement(125730..126335) 1 NC_010473.1 fimbrial-like adhesin protein 126335 yadL 6060744 yadL Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729094.1 125730 R 316385 CDS YP_001729095.1 170079775 6061374 complement(126347..126916) 1 NC_010473.1 fimbrial-like adhesin protein 126916 yadM 6061374 yadM Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729095.1 126347 R 316385 CDS YP_001729096.1 170079776 6061364 complement(126933..129530) 1 NC_010473.1 similar to the fimbrial usher protein PapC; putative outer membrane usher protein 129530 htrE 6061364 htrE Escherichia coli str. K-12 substr. DH10B putative outer membrane usher protein YP_001729096.1 126933 R 316385 CDS YP_001729097.1 170079777 6061266 complement(129565..130305) 1 NC_010473.1 putative chaperone protein EcpD 130305 ecpD 6061266 ecpD Escherichia coli str. K-12 substr. DH10B putative chaperone protein EcpD YP_001729097.1 129565 R 316385 CDS YP_001729098.1 170079778 6060575 complement(130403..130987) 1 NC_010473.1 fimbrial-like adhesin protein 130987 yadN 6060575 yadN Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729098.1 130403 R 316385 CDS YP_001729099.1 170079779 6060572 complement(131357..131836) 1 NC_010473.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 131836 folK 6060572 folK Escherichia coli str. K-12 substr. DH10B 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001729099.1 131357 R 316385 CDS YP_001729100.1 170079780 6061204 complement(131833..133230) 1 NC_010473.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 133230 pcnB 6061204 pcnB Escherichia coli str. K-12 substr. DH10B poly(A) polymerase I YP_001729100.1 131833 R 316385 CDS YP_001729101.1 170079781 6061205 complement(133290..134216) 1 NC_010473.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 134216 yadB 6061205 yadB Escherichia coli str. K-12 substr. DH10B glutamyl-Q tRNA(Asp) synthetase YP_001729101.1 133290 R 316385 CDS YP_001729102.1 170079782 6061347 complement(134253..134708) 1 NC_010473.1 RNA polymerase-binding transcription factor 134708 dksA 6061347 dksA Escherichia coli str. K-12 substr. DH10B RNA polymerase-binding transcription factor YP_001729102.1 134253 R 316385 CDS YP_001729103.1 170079783 6062338 complement(134886..135590) 1 NC_010473.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 135590 sfsA 6062338 sfsA Escherichia coli str. K-12 substr. DH10B sugar fermentation stimulation protein A YP_001729103.1 134886 R 316385 CDS YP_001729104.1 170079784 6061343 complement(135605..136135) 1 NC_010473.1 2'-5' RNA ligase 136135 ligT 6061343 ligT Escherichia coli str. K-12 substr. DH10B 2'-5' RNA ligase YP_001729104.1 135605 R 316385 CDS YP_001729105.1 170079785 6061344 136209..138638 1 NC_010473.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 138638 hrpB 6061344 hrpB Escherichia coli str. K-12 substr. DH10B ATP-dependent RNA helicase HrpB YP_001729105.1 136209 D 316385 CDS YP_001729106.1 170079786 6061336 138834..141368 1 NC_010473.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 141368 mrcB 6061336 mrcB Escherichia coli str. K-12 substr. DH10B penicillin-binding protein 1b YP_001729106.1 138834 D 316385 CDS YP_001729107.1 170079787 6062278 141588..143831 1 NC_010473.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 143831 fhuA 6062278 fhuA Escherichia coli str. K-12 substr. DH10B ferrichrome outer membrane transporter YP_001729107.1 141588 D 316385 CDS YP_001729108.1 170079788 6061278 143882..144679 1 NC_010473.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 144679 fhuC 6061278 fhuC Escherichia coli str. K-12 substr. DH10B iron-hydroxamate transporter ATP-binding subunit YP_001729108.1 143882 D 316385 CDS YP_001729109.1 170079789 6061320 144679..145569 1 NC_010473.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 145569 fhuD 6061320 fhuD Escherichia coli str. K-12 substr. DH10B iron-hydroxamate transporter substrate-binding subunit YP_001729109.1 144679 D 316385 CDS YP_001729110.1 170079790 6061265 145566..147548 1 NC_010473.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 147548 fhuB 6061265 fhuB Escherichia coli str. K-12 substr. DH10B iron-hydroxamate transporter permease subunit YP_001729110.1 145566 D 316385 CDS YP_001729111.1 170079791 6062269 complement(147706..148986) 1 NC_010473.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 148986 hemL 6062269 hemL Escherichia coli str. K-12 substr. DH10B glutamate-1-semialdehyde aminotransferase YP_001729111.1 147706 R 316385 CDS YP_001729112.1 170079792 6061211 149211..150632 1 NC_010473.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 150632 clcA 6061211 clcA Escherichia coli str. K-12 substr. DH10B chloride channel protein YP_001729112.1 149211 D 316385 CDS YP_001729113.1 170079793 6061258 150714..151058 1 NC_010473.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 151058 yadR 6061258 yadR Escherichia coli str. K-12 substr. DH10B iron-sulfur cluster insertion protein ErpA YP_001729113.1 150714 D 316385 CDS YP_001729114.1 170079794 6062317 complement(151105..151728) 1 NC_010473.1 hypothetical protein 151728 yadS 6062317 yadS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729114.1 151105 R 316385 CDS YP_001729115.1 170079795 6060553 complement(151766..152566) 1 NC_010473.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 152566 btuF 6060553 btuF Escherichia coli str. K-12 substr. DH10B vitamin B12-transporter protein BtuF YP_001729115.1 151766 R 316385 CDS YP_001729116.1 170079796 6060549 complement(152559..153257) 1 NC_010473.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 153257 pfs 6060549 pfs Escherichia coli str. K-12 substr. DH10B 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001729116.1 152559 R 316385 CDS YP_001729117.1 170079797 6060649 153341..154858 1 NC_010473.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 154858 dgt 6060649 dgt Escherichia coli str. K-12 substr. DH10B deoxyguanosinetriphosphate triphosphohydrolase YP_001729117.1 153341 D 316385 CDS YP_001729118.1 170079798 6060713 154988..156412 1 NC_010473.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 156412 degP 6060713 degP Escherichia coli str. K-12 substr. DH10B serine endoprotease YP_001729118.1 154988 D 316385 CDS YP_001729119.1 170079799 6061301 156567..157724 1 NC_010473.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 157724 cdaR 6061301 cdaR Escherichia coli str. K-12 substr. DH10B carbohydrate diacid transcriptional activator CdaR YP_001729119.1 156567 D 316385 CDS YP_001729120.1 170079800 6061246 complement(157813..158199) 1 NC_010473.1 hypothetical protein 158199 yaeH 6061246 yaeH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729120.1 157813 R 316385 CDS YP_001729121.1 170079801 6062254 complement(158361..159173) 1 NC_010473.1 phosphodiesterase YaeI 159173 yaeI 6062254 yaeI Escherichia coli str. K-12 substr. DH10B phosphodiesterase YaeI YP_001729121.1 158361 R 316385 CDS YP_001729122.1 170079802 6061233 complement(159227..160051) 1 NC_010473.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 160051 dapD 6061233 dapD Escherichia coli str. K-12 substr. DH10B 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001729122.1 159227 R 316385 CDS YP_001729123.1 170079803 6061232 complement(160082..162754) 1 NC_010473.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 162754 glnD 6061232 glnD Escherichia coli str. K-12 substr. DH10B PII uridylyl-transferase YP_001729123.1 160082 R 316385 CDS YP_001729124.1 170079804 6062247 complement(162816..163610) 1 NC_010473.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 163610 map 6062247 map Escherichia coli str. K-12 substr. DH10B methionine aminopeptidase YP_001729124.1 162816 R 316385 CDS YP_001729125.1 170079805 6059702 163978..164703 1 NC_010473.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 164703 rpsB 6059702 rpsB Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S2 YP_001729125.1 163978 D 316385 CDS YP_001729126.1 170079806 6061275 164961..165812 1 NC_010473.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 165812 tsf 6061275 tsf Escherichia coli str. K-12 substr. DH10B elongation factor Ts YP_001729126.1 164961 D 316385 CDS YP_001729127.1 170079807 6061269 165959..166684 1 NC_010473.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 166684 pyrH 6061269 pyrH Escherichia coli str. K-12 substr. DH10B uridylate kinase YP_001729127.1 165959 D 316385 CDS YP_001729128.1 170079808 6061218 166976..167533 1 NC_010473.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 167533 frr 6061218 frr Escherichia coli str. K-12 substr. DH10B ribosome recycling factor YP_001729128.1 166976 D 316385 CDS YP_001729129.1 170079809 6061216 167625..168821 1 NC_010473.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 168821 dxr 6061216 dxr Escherichia coli str. K-12 substr. DH10B 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001729129.1 167625 D 316385 CDS YP_001729130.1 170079810 6061250 169007..169768 1 NC_010473.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 169768 ispU 6061250 ispU Escherichia coli str. K-12 substr. DH10B undecaprenyl pyrophosphate synthase YP_001729130.1 169007 D 316385 CDS YP_001729131.1 170079811 6060529 169781..170638 1 NC_010473.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 170638 cdsA 6060529 cdsA Escherichia coli str. K-12 substr. DH10B CDP-diglyceride synthase YP_001729131.1 169781 D 316385 CDS YP_001729132.1 170079812 6060701 170650..172002 1 NC_010473.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 172002 rseP 6060701 rseP Escherichia coli str. K-12 substr. DH10B zinc metallopeptidase RseP YP_001729132.1 170650 D 316385 CDS YP_001729133.1 170079813 6060629 172032..174464 1 NC_010473.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 174464 ecfK 6060629 ecfK Escherichia coli str. K-12 substr. DH10B outer membrane protein assembly factor YaeT YP_001729133.1 172032 D 316385 CDS YP_001729134.1 170079814 6060697 174586..175071 1 NC_010473.1 periplasmic chaperone 175071 skp 6060697 skp Escherichia coli str. K-12 substr. DH10B periplasmic chaperone YP_001729134.1 174586 D 316385 CDS YP_001729135.1 170079815 6061150 175075..176100 1 NC_010473.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 176100 lpxD 6061150 lpxD Escherichia coli str. K-12 substr. DH10B UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001729135.1 175075 D 316385 CDS YP_001729136.1 170079816 6061195 176205..176660 1 NC_010473.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 176660 fabZ 6061195 fabZ Escherichia coli str. K-12 substr. DH10B (3R)-hydroxymyristoyl-ACP dehydratase YP_001729136.1 176205 D 316385 CDS YP_001729137.1 170079817 6062258 176664..177452 1 NC_010473.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 177452 lpxA 6062258 lpxA Escherichia coli str. K-12 substr. DH10B UDP-N-acetylglucosamine acyltransferase YP_001729137.1 176664 D 316385 CDS YP_001729138.1 170079818 6061005 177452..178600 1 NC_010473.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 178600 lpxB 6061005 lpxB Escherichia coli str. K-12 substr. DH10B lipid-A-disaccharide synthase YP_001729138.1 177452 D 316385 CDS YP_001729139.1 170079819 6061147 178597..179193 1 NC_010473.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 179193 rnhB 6061147 rnhB Escherichia coli str. K-12 substr. DH10B ribonuclease HII YP_001729139.1 178597 D 316385 CDS YP_001729140.1 170079820 6061238 179230..182712 1 NC_010473.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 182712 dnaE 6061238 dnaE Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit alpha YP_001729140.1 179230 D 316385 CDS YP_001729141.1 170079821 6062185 182725..183684 1 NC_010473.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 183684 accA 6062185 accA Escherichia coli str. K-12 substr. DH10B acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001729141.1 182725 D 316385 CDS YP_001729142.1 170079822 6061138 183783..185924 1 NC_010473.1 lysine decarboxylase 2, constitutive 185924 ldcC 6061138 ldcC Escherichia coli str. K-12 substr. DH10B lysine decarboxylase 2, constitutive YP_001729142.1 183783 D 316385 CDS YP_001729143.1 170079823 6061135 185981..186370 1 NC_010473.1 hypothetical protein 186370 yaeR 6061135 yaeR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729143.1 185981 D 316385 CDS YP_001729144.1 170079824 6061222 186435..187733 1 NC_010473.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 187733 tilS 6061222 tilS Escherichia coli str. K-12 substr. DH10B tRNA(Ile)-lysidine synthetase YP_001729144.1 186435 D 316385 CDS YP_001729145.1 170079825 6062062 complement(187782..188036) 1 NC_010473.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 188036 rof 6062062 rof Escherichia coli str. K-12 substr. DH10B Rho-binding antiterminator YP_001729145.1 187782 R 316385 CDS YP_001729146.1 170079826 6062236 complement(188029..188229) 1 NC_010473.1 hypothetical protein 188229 yaeP 6062236 yaeP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729146.1 188029 R 316385 CDS YP_001729147.1 170079827 6062233 188395..188940 1 NC_010473.1 hypothetical protein 188940 yaeQ 6062233 yaeQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729147.1 188395 D 316385 CDS YP_001729148.1 170079828 6060616 188937..189359 1 NC_010473.1 peptidyl-tRNA hydrolase domain-containing protein 189359 yaeJ 6060616 yaeJ Escherichia coli str. K-12 substr. DH10B peptidyl-tRNA hydrolase domain-containing protein YP_001729148.1 188937 D 316385 CDS YP_001729149.1 170079829 6060499 189373..190083 1 NC_010473.1 lipoprotein involved with copper homeostasis and adhesion 190083 nlpE 6060499 nlpE Escherichia coli str. K-12 substr. DH10B lipoprotein involved with copper homeostasis and adhesion YP_001729149.1 189373 D 316385 CDS YP_001729150.1 170079830 6061203 complement(190283..191107) 1 NC_010473.1 hypothetical protein 191107 yaeF 6061203 yaeF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729150.1 190283 R 316385 CDS YP_001729151.1 170079831 6061202 complement(191161..192879) 1 NC_010473.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 192879 proS 6061202 proS Escherichia coli str. K-12 substr. DH10B prolyl-tRNA synthetase YP_001729151.1 191161 R 316385 CDS YP_001729152.1 170079832 6061019 complement(192991..193698) 1 NC_010473.1 hypothetical protein 193698 yaeB 6061019 yaeB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729152.1 192991 R 316385 CDS YP_001729153.1 170079833 6062189 complement(193695..194099) 1 NC_010473.1 outer membrane lipoprotein 194099 rcsF 6062189 rcsF Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein YP_001729153.1 193695 R 316385 CDS YP_001729154.1 170079834 6062220 complement(194217..195032) 1 NC_010473.1 DL-methionine transporter substrate-binding subunit 195032 metQ 6062220 metQ Escherichia coli str. K-12 substr. DH10B DL-methionine transporter substrate-binding subunit YP_001729154.1 194217 R 316385 CDS YP_001729155.1 170079835 6062218 complement(195072..195725) 1 NC_010473.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 195725 metI 6062218 metI Escherichia coli str. K-12 substr. DH10B DL-methionine transporter permease YP_001729155.1 195072 R 316385 CDS YP_001729156.1 170079836 6061111 complement(195718..196749) 1 NC_010473.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 196749 metN 6061111 metN Escherichia coli str. K-12 substr. DH10B DL-methionine transporter ATP-binding subunit YP_001729156.1 195718 R 316385 CDS YP_001729157.1 170079837 6061142 196937..197512 1 NC_010473.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 197512 gmhB 6061142 gmhB Escherichia coli str. K-12 substr. DH10B D,D-heptose 1,7-bisphosphate phosphatase YP_001729157.1 196937 D 316385 CDS YP_001729158.1 170079838 6059800 203271..204074 1 NC_010473.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 204074 dkgB 6059800 dkgB Escherichia coli str. K-12 substr. DH10B 2,5-diketo-D-gluconate reductase B YP_001729158.1 203271 D 316385 CDS YP_001729159.1 170079839 6061101 complement(204071..204985) 1 NC_010473.1 DNA-binding transcriptional regulator 204985 yafC 6061101 yafC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729159.1 204071 R 316385 CDS YP_001729160.1 170079840 6061105 205226..206026 1 NC_010473.1 hypothetical protein 206026 yafD 6061105 yafD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729160.1 205226 D 316385 CDS YP_001729161.1 170079841 6061095 206030..206653 1 NC_010473.1 S-adenosyl-L-methionine-dependent methyltransferase 206653 yafE 6061095 yafE Escherichia coli str. K-12 substr. DH10B S-adenosyl-L-methionine-dependent methyltransferase YP_001729161.1 206030 D 316385 CDS YP_001729162.1 170079842 6060811 complement(206701..208059) 1 NC_010473.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 208059 mltD 6060811 mltD Escherichia coli str. K-12 substr. DH10B membrane-bound lytic murein transglycosylase D YP_001729162.1 206701 R 316385 CDS YP_001729163.1 170079843 6062135 complement(208131..208886) 1 NC_010473.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 208886 gloB 6062135 gloB Escherichia coli str. K-12 substr. DH10B hydroxyacylglutathione hydrolase YP_001729163.1 208131 R 316385 CDS YP_001729164.1 170079844 6060678 208920..209642 1 NC_010473.1 S-adenosyl-L-methionine-dependent methyltransferase 209642 yafS 6060678 yafS Escherichia coli str. K-12 substr. DH10B S-adenosyl-L-methionine-dependent methyltransferase YP_001729164.1 208920 D 316385 CDS YP_001729165.1 170079845 6060677 complement(209639..210106) 1 NC_010473.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 210106 rnhA 6060677 rnhA Escherichia coli str. K-12 substr. DH10B ribonuclease H YP_001729165.1 209639 R 316385 CDS YP_001729166.1 170079846 6061081 210171..210902 1 NC_010473.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 210902 dnaQ 6061081 dnaQ Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit epsilon YP_001729166.1 210171 D 316385 CDS YP_001729167.1 170079847 6059983 211439..212224 1 NC_010473.1 aminopeptidase 212224 yafT 6059983 yafT Escherichia coli str. K-12 substr. DH10B aminopeptidase YP_001729167.1 211439 D 316385 CDS YP_001729168.1 170079848 6060276 complement(213523..214293) 1 NC_010473.1 hypothetical protein 214293 yafV 6060276 yafV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729168.1 213523 R 316385 CDS YP_001729169.1 170079849 6061167 214447..214920 1 NC_010473.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 214920 ivy 6061167 ivy Escherichia coli str. K-12 substr. DH10B C-lysozyme inhibitor YP_001729169.1 214447 D 316385 CDS YP_001729170.1 170079850 6062199 complement(214963..217407) 1 NC_010473.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 217407 fadE 6062199 fadE Escherichia coli str. K-12 substr. DH10B acyl-CoA dehydrogenase YP_001729170.1 214963 R 316385 CDS YP_001729171.1 170079851 6061162 217647..218225 1 NC_010473.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 218225 gmhA 6061162 gmhA Escherichia coli str. K-12 substr. DH10B phosphoheptose isomerase YP_001729171.1 217647 D 316385 CDS YP_001729172.1 170079852 6061121 218431..219198 1 NC_010473.1 contains the nonsynonymous change Q80L; amidotransferase 219198 yafJ 6061121 yafJ Escherichia coli str. K-12 substr. DH10B amidotransferase YP_001729172.1 218431 D 316385 CDS YP_001729173.1 170079853 6061066 complement(219169..219909) 1 NC_010473.1 hypothetical protein 219909 yafK 6061066 yafK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729173.1 219169 R 316385 CDS YP_001729174.1 170079854 6061153 complement(220065..220343) 1 NC_010473.1 toxin of the YafQ-DinJ toxin-antitoxin system 220343 yafQ 6061153 yafQ Escherichia coli str. K-12 substr. DH10B toxin of the YafQ-DinJ toxin-antitoxin system YP_001729174.1 220065 R 316385 CDS YP_001729175.1 170079855 6061114 complement(220346..220606) 1 NC_010473.1 antitoxin of YafQ-DinJ toxin-antitoxin system 220606 dinJ 6061114 dinJ Escherichia coli str. K-12 substr. DH10B antitoxin of YafQ-DinJ toxin-antitoxin system YP_001729175.1 220346 R 316385 CDS YP_001729176.1 170079856 6061149 220816..221565 1 NC_010473.1 contains synonymous mutation (G to T) at position 36; C40 family peptidase 221565 yafL 6061149 yafL Escherichia coli str. K-12 substr. DH10B C40 family peptidase YP_001729176.1 220816 D 316385 CDS YP_001729177.1 170079857 6062152 221741..222238 1 NC_010473.1 hypothetical protein 222238 yafM 6062152 yafM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729177.1 221741 D 316385 CDS YP_001729178.1 170079858 6060198 225002..226057 1 NC_010473.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 226057 dinB 6060198 dinB Escherichia coli str. K-12 substr. DH10B DNA polymerase IV YP_001729178.1 225002 D 316385 CDS YP_001729179.1 170079859 6061100 226109..226402 1 NC_010473.1 putative antitoxin of the YafO-YafN toxin-antitoxin system 226402 yafN 6061100 yafN Escherichia coli str. K-12 substr. DH10B putative antitoxin of the YafO-YafN toxin-antitoxin system YP_001729179.1 226109 D 316385 CDS YP_001729180.1 170079860 6060580 226405..226803 1 NC_010473.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; putative toxin YafO 226803 yafO 6060580 yafO Escherichia coli str. K-12 substr. DH10B putative toxin YafO YP_001729180.1 226405 D 316385 CDS YP_001729181.1 170079861 6060584 226813..227265 1 NC_010473.1 hypothetical protein 227265 yafP 6060584 yafP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729181.1 226813 D 316385 CDS YP_001729182.1 170079862 6060105 complement(228363..229820) 1 NC_010473.1 aminoacyl-histidine dipeptidase 229820 pepD 6060105 pepD Escherichia coli str. K-12 substr. DH10B aminoacyl-histidine dipeptidase YP_001729182.1 228363 R 316385 CDS YP_001729183.1 170079863 6060518 230081..230539 1 NC_010473.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 230539 gpt 6060518 gpt Escherichia coli str. K-12 substr. DH10B xanthine-guanine phosphoribosyltransferase YP_001729183.1 230081 D 316385 CDS YP_001729184.1 170079864 6061367 230631..231875 1 NC_010473.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 231875 frsA 6061367 frsA Escherichia coli str. K-12 substr. DH10B fermentation/respiration switch protein YP_001729184.1 230631 D 316385 CDS YP_001729185.1 170079865 6061454 231933..232334 1 NC_010473.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 232334 crl 6061454 crl Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator Crl YP_001729185.1 231933 D 316385 CDS YP_001729186.1 170079866 6061732 complement(232373..233428) 1 NC_010473.1 outer membrane phosphoporin protein E 233428 phoE 6061732 phoE Escherichia coli str. K-12 substr. DH10B outer membrane phosphoporin protein E YP_001729186.1 232373 R 316385 CDS YP_001729187.1 170079867 6061924 233716..234819 1 NC_010473.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 234819 proB 6061924 proB Escherichia coli str. K-12 substr. DH10B gamma-glutamyl kinase YP_001729187.1 233716 D 316385 CDS YP_001729188.1 170079868 6061964 234831..236084 1 NC_010473.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 236084 proA 6061964 proA Escherichia coli str. K-12 substr. DH10B gamma-glutamyl phosphate reductase YP_001729188.1 234831 D 316385 CDS YP_001729189.1 170079869 6058464 complement(236656..236997) 1 NC_010473.1 CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system 236997 ykfI 6058464 ykfI Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system YP_001729189.1 236656 R 316385 CDS YP_001729190.1 170079870 6062075 complement(237018..237335) 1 NC_010473.1 CP4-6 prophage; antitoxin of the YkfI-YafW toxin-antitoxin system 237335 yafW 6062075 yafW Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; antitoxin of the YkfI-YafW toxin-antitoxin system YP_001729190.1 237018 R 316385 CDS YP_001729191.1 170079871 6062127 complement(237354..237575) 1 NC_010473.1 hypothetical protein 237575 ykfH 6062127 ykfH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729191.1 237354 R 316385 CDS YP_001729192.1 170079872 6062145 complement(237584..238060) 1 NC_010473.1 CP4-6 prophage; DNA repair protein 238060 ykfG 6062145 ykfG Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; DNA repair protein YP_001729192.1 237584 R 316385 CDS YP_001729193.1 170079873 6062115 complement(238076..238534) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 238534 yafX 6062115 yafX Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729193.1 238076 R 316385 CDS YP_001729194.1 170079874 6062168 complement(238632..238871) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 238871 ykfF 6062168 ykfF Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729194.1 238632 R 316385 CDS YP_001729195.1 170079875 6062179 complement(238948..239415) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 239415 ykfB 6062179 ykfB Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729195.1 238948 R 316385 CDS YP_001729196.1 170079876 6062150 complement(239438..239881) 1 NC_010473.1 CP4-6 prophage; inner membrane lipoprotein 239881 yafY 6062150 yafY Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; inner membrane lipoprotein YP_001729196.1 239438 R 316385 CDS YP_001729197.1 170079877 6059344 complement(240512..241333) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 241333 yafZ 6059344 yafZ Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729197.1 240512 R 316385 CDS YP_001729198.1 170079878 6062289 complement(241425..242288) 1 NC_010473.1 CP4-6 prophage; GTP-binding protein 242288 ykfA 6062289 ykfA Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; GTP-binding protein YP_001729198.1 241425 R 316385 CDS YP_001729199.1 170079879 6062299 complement(242617..243510) 1 NC_010473.1 CP4-6 prophage; DNA-binding transcriptional regulator 243510 perR 6062299 perR Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; DNA-binding transcriptional regulator YP_001729199.1 242617 R 316385 CDS YP_001729200.1 170079880 6062302 243570..243974 1 NC_010473.1 CP4-6 prophage; partial regulator of insertion element IS911A 243974 insN-1 6062302 insN-1 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; partial regulator of insertion element IS911A YP_001729200.1 243570 D 316385 CDS YP_001729201.1 170079881 6062312 243931..245082 1 NC_010473.1 CP4-6 prophage; IS30 transposase 245082 insI-1 6062312 insI-1 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; IS30 transposase YP_001729201.1 243931 D 316385 CDS YP_001729202.1 170079882 6062213 245158..245583 1 NC_010473.1 CP4-6 prophage; partial transposase of insertion element IS911A 245583 insO-1 6062213 insO-1 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; partial transposase of insertion element IS911A YP_001729202.1 245158 D 316385 CDS YP_001729203.1 170079883 6059560 complement(247429..248445) 1 NC_010473.1 CP4-6 prophage; IS5 transposase and trans-activator 248445 insH-1 6059560 insH-1 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; IS5 transposase and trans-activator YP_001729203.1 247429 R 316385 CDS YP_001729204.1 170079884 6062339 248653..250056 1 NC_010473.1 S-methylmethionine transporter 250056 mmuP 6062339 mmuP Escherichia coli str. K-12 substr. DH10B S-methylmethionine transporter YP_001729204.1 248653 D 316385 CDS YP_001729205.1 170079885 6062419 250043..250975 1 NC_010473.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 250975 mmuM 6062419 mmuM Escherichia coli str. K-12 substr. DH10B homocysteine methyltransferase YP_001729205.1 250043 D 316385 CDS YP_001729206.1 170079886 6060364 complement(251084..252130) 1 NC_010473.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 252130 fbpC 6060364 fbpC Escherichia coli str. K-12 substr. DH10B ferric transporter ATP-binding subunit YP_001729206.1 251084 R 316385 CDS YP_001729207.1 170079887 6062282 complement(252142..252504) 1 NC_010473.1 CP4-6 prophage; ferric ABC transporter membrane protein 252504 afuB 6062282 afuB Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; ferric ABC transporter membrane protein YP_001729207.1 252142 R 316385 CDS YP_001729208.1 170079888 6062407 complement(252506..253009) 1 NC_010473.1 CP4-6 prophage; IS1 transposase InsAB' 253009 insB-2 6062407 insB-2 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; IS1 transposase InsAB' YP_001729208.1 252506 R 316385 CDS YP_001729209.1 170079889 6062389 complement(252928..253203) 1 NC_010473.1 CP4-6 prophage; IS1 repressor protein InsA 253203 insA-2 6062389 insA-2 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; IS1 repressor protein InsA YP_001729209.1 252928 R 316385 CDS YP_001729210.1 170079890 6062382 complement(253352..253690) 1 NC_010473.1 IS protein 253690 ykgN 6062382 ykgN Escherichia coli str. K-12 substr. DH10B IS protein YP_001729210.1 253352 R 316385 CDS YP_001729211.1 170079891 6062323 complement(253713..254063) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 254063 yagB 6062323 yagB Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729211.1 253713 R 316385 CDS YP_001729212.1 170079892 6062417 complement(254157..255311) 1 NC_010473.1 CP4-6 prophage; DNA-binding transcriptional regulator 255311 yagA 6062417 yagA Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; DNA-binding transcriptional regulator YP_001729212.1 254157 R 316385 CDS YP_001729213.1 170079893 6060903 255585..256514 1 NC_010473.1 CP4-6 prophage; lyase/synthase 256514 yagE 6060903 yagE Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; lyase/synthase YP_001729213.1 255585 D 316385 CDS YP_001729214.1 170079894 6062281 256529..258496 1 NC_010473.1 contains synonymous mutation (T to G) at position 1335; hypothetical protein 258496 yagF 6062281 yagF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729214.1 256529 D 316385 CDS YP_001729215.1 170079895 6058916 258723..260105 1 NC_010473.1 uncharacterized member of the GPH family of galactose-pentose-hexuronide transporters; putative symporter YagG 260105 yagG 6058916 yagG Escherichia coli str. K-12 substr. DH10B putative symporter YagG YP_001729215.1 258723 D 316385 CDS YP_001729216.1 170079896 6058952 260117..261727 1 NC_010473.1 CP4-6 prophage; xylosidase/arabinosidase 261727 yagH 6058952 yagH Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; xylosidase/arabinosidase YP_001729216.1 260117 D 316385 CDS YP_001729217.1 170079897 6060287 complement(264075..265079) 1 NC_010473.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase; when both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III; ornithine carbamoyltransferase subunit F 265079 argF 6060287 argF Escherichia coli str. K-12 substr. DH10B ornithine carbamoyltransferase subunit F YP_001729217.1 264075 R 316385 CDS YP_001729218.1 170079898 6061877 complement(265423..265926) 1 NC_010473.1 CP4-6 prophage; IS1 transposase InsAB' 265926 insB-3 6061877 insB-3 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; IS1 transposase InsAB' YP_001729218.1 265423 R 316385 CDS YP_001729219.1 170079899 6062170 complement(265845..266120) 1 NC_010473.1 CP4-6 prophage; IS1 repressor protein InsA 266120 insA-3 6062170 insA-3 Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; IS1 repressor protein InsA YP_001729219.1 265845 R 316385 CDS YP_001729220.1 170079900 6062311 266274..267005 1 NC_010473.1 CP4-6 prophage; hypothetical protein 267005 yagJ 6062311 yagJ Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729220.1 266274 D 316385 CDS YP_001729221.1 170079901 6058896 complement(267096..267722) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 267722 yagK 6058896 yagK Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729221.1 267096 R 316385 CDS YP_001729222.1 170079902 6059304 complement(267994..268692) 1 NC_010473.1 CP4-6 prophage; DNA-binding protein 268692 yagL 6059304 yagL Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; DNA-binding protein YP_001729222.1 267994 R 316385 CDS YP_001729223.1 170079903 6059821 complement(268719..269573) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 269573 yagM 6059821 yagM Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729223.1 268719 R 316385 CDS YP_001729224.1 170079904 6060265 complement(269913..270353) 1 NC_010473.1 CP4-6 prophage; hypothetical protein 270353 yagN 6060265 yagN Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; hypothetical protein YP_001729224.1 269913 R 316385 CDS YP_001729225.1 170079905 6060277 complement(270470..271870) 1 NC_010473.1 CP4-6 prophage; phage integrase 271870 intF 6060277 intF Escherichia coli str. K-12 substr. DH10B CP4-6 prophage; phage integrase YP_001729225.1 270470 R 316385 CDS YP_001729226.1 170079906 6062079 complement(272155..272565) 1 NC_010473.1 transcriptional regulator 272565 yagP 6062079 yagP Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001729226.1 272155 R 316385 CDS YP_001729227.1 170079907 6060039 complement(272544..273500) 1 NC_010473.1 hypothetical protein 273500 yagQ 6060039 yagQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729227.1 272544 R 316385 CDS YP_001729228.1 170079908 6061894 complement(273510..275708) 1 NC_010473.1 oxidoreductase 275708 yagR 6061894 yagR Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001729228.1 273510 R 316385 CDS YP_001729229.1 170079909 6062103 complement(275705..276661) 1 NC_010473.1 oxidoreductase 276661 yagS 6062103 yagS Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001729229.1 275705 R 316385 CDS YP_001729230.1 170079910 6058920 complement(276658..277347) 1 NC_010473.1 putative xanthine dehydrogenase iron-sulfur-binding subunit 277347 yagT 6058920 yagT Escherichia coli str. K-12 substr. DH10B putative xanthine dehydrogenase iron-sulfur-binding subunit YP_001729230.1 276658 R 316385 CDS YP_001729231.1 170079911 6059793 277765..278379 1 NC_010473.1 inner membrane protein 278379 yagU 6059793 yagU Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729231.1 277765 D 316385 CDS YP_001729232.1 170079912 6059806 complement(278627..278956) 1 NC_010473.1 ferredoxin 278956 ykgJ 6059806 ykgJ Escherichia coli str. K-12 substr. DH10B ferredoxin YP_001729232.1 278627 R 316385 CDS YP_001729233.1 170079913 6061933 complement(279269..279979) 1 NC_010473.1 hypothetical protein 279979 yagV 6061933 yagV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729233.1 279269 R 316385 CDS YP_001729234.1 170079914 6061579 complement(279948..281591) 1 NC_010473.1 receptor 281591 yagW 6061579 yagW Escherichia coli str. K-12 substr. DH10B receptor YP_001729234.1 279948 R 316385 CDS YP_001729235.1 170079915 6061133 complement(281581..284106) 1 NC_010473.1 aromatic compound dioxygenase 284106 yagX 6061133 yagX Escherichia coli str. K-12 substr. DH10B aromatic compound dioxygenase YP_001729235.1 281581 R 316385 CDS YP_001729236.1 170079916 6060675 complement(284132..284800) 1 NC_010473.1 hypothetical protein 284800 matC 6060675 matC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729236.1 284132 R 316385 CDS YP_001729237.1 170079917 6061956 complement(284858..285445) 1 NC_010473.1 MAT fimbrillin 285445 matB 6061956 matB Escherichia coli str. K-12 substr. DH10B MAT fimbrillin YP_001729237.1 284858 R 316385 CDS YP_001729238.1 170079918 6058216 complement(285520..286110) 1 NC_010473.1 regulator 286110 matA 6058216 matA Escherichia coli str. K-12 substr. DH10B regulator YP_001729238.1 285520 R 316385 CDS YP_001729239.1 170079919 6058242 286886..287113 1 NC_010473.1 hypothetical protein 287113 ykgL 6058242 ykgL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729239.1 286886 D 316385 CDS YP_001729240.1 170079920 6058268 complement(287148..287288) 1 NC_010473.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 287288 rpmJ 6058268 rpmJ Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L36 YP_001729240.1 287148 R 316385 CDS YP_001729241.1 170079921 6058420 complement(287288..287551) 1 NC_010473.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 287551 rpmE2 6058420 rpmE2 Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L31 YP_001729241.1 287288 R 316385 CDS YP_001729242.1 170079922 6058618 289131..290018 1 NC_010473.1 attaching and effacing protein, pathogenesis factor 290018 eaeH 6058618 eaeH Escherichia coli str. K-12 substr. DH10B attaching and effacing protein, pathogenesis factor YP_001729242.1 289131 D 316385 CDS YP_001729243.1 170079923 6059106 290056..290364 1 NC_010473.1 IS3 element protein InsE 290364 insE-1 6059106 insE-1 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsE YP_001729243.1 290056 D 316385 CDS YP_001729244.1 170079924 6058762 290361..291227 1 NC_010473.1 IS3 element protein InsF 291227 insF-1 6058762 insF-1 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsF YP_001729244.1 290361 D 316385 CDS YP_001729245.1 170079925 6058881 complement(291224..291910) 1 NC_010473.1 DNA-binding transcriptional regulator 291910 ykgA 6058881 ykgA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729245.1 291224 R 316385 CDS YP_001729246.1 170079926 6059081 complement(292500..293093) 1 NC_010473.1 inner membrane protein 293093 ykgB 6059081 ykgB Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729246.1 292500 R 316385 CDS YP_001729247.1 170079927 6059116 complement(293105..293341) 1 NC_010473.1 hypothetical protein 293341 ykgI 6059116 ykgI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729247.1 293105 R 316385 CDS YP_001729248.1 170079928 6059121 complement(293450..294775) 1 NC_010473.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 294775 ykgC 6059121 ykgC Escherichia coli str. K-12 substr. DH10B pyridine nucleotide-disulfide oxidoreductase YP_001729248.1 293450 R 316385 CDS YP_001729249.1 170079929 6059137 295001..295855 1 NC_010473.1 DNA-binding transcriptional regulator 295855 ykgD 6059137 ykgD Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729249.1 295001 D 316385 CDS YP_001729250.1 170079930 6059167 296382..297101 1 NC_010473.1 oxidoreductase 297101 ykgE 6059167 ykgE Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001729250.1 296382 D 316385 CDS YP_001729251.1 170079931 6059187 297112..298539 1 NC_010473.1 amino acid dehydrogenase 298539 ykgF 6059187 ykgF Escherichia coli str. K-12 substr. DH10B amino acid dehydrogenase YP_001729251.1 297112 D 316385 CDS YP_001729252.1 170079932 6059198 298532..299227 1 NC_010473.1 transporter 299227 ykgG 6059198 ykgG Escherichia coli str. K-12 substr. DH10B transporter YP_001729252.1 298532 D 316385 CDS YP_001729253.1 170079933 6059205 complement(299470..300138) 1 NC_010473.1 inner membrane protein 300138 ykgH 6059205 ykgH Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729253.1 299470 R 316385 CDS YP_001729254.1 170079934 6059685 complement(300351..302021) 1 NC_010473.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 302021 betA 6059685 betA Escherichia coli str. K-12 substr. DH10B choline dehydrogenase YP_001729254.1 300351 R 316385 CDS YP_001729255.1 170079935 6059213 complement(302035..303507) 1 NC_010473.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 303507 betB 6059213 betB Escherichia coli str. K-12 substr. DH10B betaine aldehyde dehydrogenase YP_001729255.1 302035 R 316385 CDS YP_001729256.1 170079936 6059246 complement(303521..304108) 1 NC_010473.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 304108 betI 6059246 betI Escherichia coli str. K-12 substr. DH10B transcriptional regulator BetI YP_001729256.1 303521 R 316385 CDS YP_001729257.1 170079937 6059248 304237..306270 1 NC_010473.1 proton-motive-force-driven choline transporter; choline transport protein BetT 306270 betT 6059248 betT Escherichia coli str. K-12 substr. DH10B choline transport protein BetT YP_001729257.1 304237 D 316385 CDS YP_001729258.1 170079938 6059249 307145..308233 1 NC_010473.1 DNA-binding transcriptional regulator 308233 yahA 6059249 yahA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729258.1 307145 D 316385 CDS YP_001729259.1 170079939 6059254 complement(308275..309207) 1 NC_010473.1 DNA-binding transcriptional regulator 309207 yahB 6059254 yahB Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729259.1 308275 R 316385 CDS YP_001729260.1 170079940 6059257 complement(309299..309796) 1 NC_010473.1 inner membrane protein 309796 yahC 6059257 yahC Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729260.1 309299 R 316385 CDS YP_001729261.1 170079941 6059261 310054..310659 1 NC_010473.1 transcriptional regulator 310659 yahD 6059261 yahD Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001729261.1 310054 D 316385 CDS YP_001729262.1 170079942 6059280 310699..311562 1 NC_010473.1 hypothetical protein 311562 yahE 6059280 yahE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729262.1 310699 D 316385 CDS YP_001729263.1 170079943 6059281 311552..313099 1 NC_010473.1 acyl-CoA synthetase 313099 yahF 6059281 yahF Escherichia coli str. K-12 substr. DH10B acyl-CoA synthetase YP_001729263.1 311552 D 316385 CDS YP_001729264.1 170079944 6059282 314014..315225 1 NC_010473.1 putative 3-hydroxyphenylpropionic transporter MhpT 315225 mhpT 6059282 mhpT Escherichia coli str. K-12 substr. DH10B putative 3-hydroxyphenylpropionic transporter MhpT YP_001729264.1 314014 D 316385 CDS YP_001729265.1 170079945 6059284 315327..315866 1 NC_010473.1 nucleoprotein/polynucleotide-associated enzyme 315866 yaiL 6059284 yaiL Escherichia coli str. K-12 substr. DH10B nucleoprotein/polynucleotide-associated enzyme YP_001729265.1 315327 D 316385 CDS YP_001729266.1 170079946 6059309 complement(316090..316923) 1 NC_010473.1 esterase 316923 frmB 6059309 frmB Escherichia coli str. K-12 substr. DH10B esterase YP_001729266.1 316090 R 316385 CDS YP_001729267.1 170079947 6059313 complement(317017..318126) 1 NC_010473.1 alcohol dehydrogenase 318126 frmA 6059313 frmA Escherichia coli str. K-12 substr. DH10B alcohol dehydrogenase YP_001729267.1 317017 R 316385 CDS YP_001729268.1 170079948 6059318 complement(318161..318436) 1 NC_010473.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 318436 frmR 6059318 frmR Escherichia coli str. K-12 substr. DH10B regulator protein FrmR YP_001729268.1 318161 R 316385 CDS YP_001729269.1 170079949 6059321 complement(318624..319397) 1 NC_010473.1 hypothetical protein 319397 yaiO 6059321 yaiO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729269.1 318624 R 316385 CDS YP_001729270.1 170079950 6059144 319861..320271 1 NC_010473.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 320271 insC-1 6059144 insC-1 Escherichia coli str. K-12 substr. DH10B insertion sequence 2 OrfA protein YP_001729270.1 319861 D 316385 CDS YP_001729271.1 170079951 6059120 320229..321134 1 NC_010473.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 321134 insD-1 6059120 insD-1 Escherichia coli str. K-12 substr. DH10B insertion element IS2 transposase InsD YP_001729271.1 320229 D 316385 CDS YP_001729272.1 170079952 6059324 complement(321294..322490) 1 NC_010473.1 glucosyltransferase 322490 yaiP 6059324 yaiP Escherichia coli str. K-12 substr. DH10B glucosyltransferase YP_001729272.1 321294 R 316385 CDS YP_001729273.1 170079953 6059325 complement(322614..323171) 1 NC_010473.1 hypothetical protein 323171 yaiS 6059325 yaiS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729273.1 322614 R 316385 CDS YP_001729274.1 170079954 6059327 323787..324749 1 NC_010473.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 324749 tauA 6059327 tauA Escherichia coli str. K-12 substr. DH10B taurine transporter substrate binding subunit YP_001729274.1 323787 D 316385 CDS YP_001729275.1 170079955 6059331 324762..325529 1 NC_010473.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 325529 tauB 6059331 tauB Escherichia coli str. K-12 substr. DH10B taurine transporter ATP-binding subunit YP_001729275.1 324762 D 316385 CDS YP_001729276.1 170079956 6059337 325526..326353 1 NC_010473.1 taurine transporter subunit 326353 tauC 6059337 tauC Escherichia coli str. K-12 substr. DH10B taurine transporter subunit YP_001729276.1 325526 D 316385 CDS YP_001729277.1 170079957 6059341 326350..327201 1 NC_010473.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 327201 tauD 6059341 tauD Escherichia coli str. K-12 substr. DH10B taurine dioxygenase YP_001729277.1 326350 D 316385 CDS YP_001729278.1 170079958 6059343 complement(327308..328282) 1 NC_010473.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 328282 hemB 6059343 hemB Escherichia coli str. K-12 substr. DH10B delta-aminolevulinic acid dehydratase YP_001729278.1 327308 R 316385 CDS YP_001729279.1 170079959 6059354 complement(328452..328721) 1 NC_010473.1 hypothetical protein 328721 ykiB 6059354 ykiB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729279.1 328452 R 316385 CDS YP_001729280.1 170079960 6058693 complement(330294..331160) 1 NC_010473.1 IS3 element protein InsF 331160 insF-2 6058693 insF-2 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsF YP_001729280.1 330294 R 316385 CDS YP_001729281.1 170079961 6059361 complement(331157..331465) 1 NC_010473.1 IS3 element protein InsE 331465 insE-2 6059361 insE-2 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsE YP_001729281.1 331157 R 316385 CDS YP_001729282.1 170079962 6059376 333016..333684 1 NC_010473.1 putative DNA-binding transcriptional regulator 333684 yaiV 6059376 yaiV Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001729282.1 333016 D 316385 CDS YP_001729283.1 170079963 6059396 complement(333685..334842) 1 NC_010473.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 334842 ampH 6059396 ampH Escherichia coli str. K-12 substr. DH10B beta-lactam binding protein AmpH YP_001729283.1 333685 R 316385 CDS YP_001729284.1 170079964 6059398 335194..336414 1 NC_010473.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 336414 sbmA 6059398 sbmA Escherichia coli str. K-12 substr. DH10B transporter YP_001729284.1 335194 D 316385 CDS YP_001729285.1 170079965 6059400 336427..337521 1 NC_010473.1 DNA-binding transcriptional regulator 337521 yaiW 6059400 yaiW Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729285.1 336427 D 316385 CDS YP_001729286.1 170079966 6059401 complement(337580..337888) 1 NC_010473.1 inner membrane protein 337888 yaiY 6059401 yaiY Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729286.1 337580 R 316385 CDS YP_001729287.1 170079967 6059406 338148..338360 1 NC_010473.1 inner membrane protein 338360 yaiZ 6059406 yaiZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729287.1 338148 D 316385 CDS YP_001729288.1 170079968 6059408 complement(338384..339478) 1 NC_010473.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 339478 ddl 6059408 ddl Escherichia coli str. K-12 substr. DH10B D-alanyl-alanine synthetase A YP_001729288.1 338384 R 316385 CDS YP_001729289.1 170079969 6059414 339941..340201 1 NC_010473.1 hypothetical protein 340201 iraP 6059414 iraP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729289.1 339941 D 316385 CDS YP_001729290.1 170079970 6059419 340302..341717 1 NC_010473.1 alkaline phosphatase 341717 phoA 6059419 phoA Escherichia coli str. K-12 substr. DH10B alkaline phosphatase YP_001729290.1 340302 D 316385 CDS YP_001729291.1 170079971 6059422 341836..342156 1 NC_010473.1 hypothetical protein 342156 psiF 6059422 psiF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729291.1 341836 D 316385 CDS YP_001729292.1 170079972 6059436 342258..343373 1 NC_010473.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 343373 adrA 6059436 adrA Escherichia coli str. K-12 substr. DH10B diguanylate cyclase AdrA YP_001729292.1 342258 D 316385 CDS YP_001729293.1 170079973 6059440 complement(343390..344199) 1 NC_010473.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 344199 proC 6059440 proC Escherichia coli str. K-12 substr. DH10B pyrroline-5-carboxylate reductase YP_001729293.1 343390 R 316385 CDS YP_001729294.1 170079974 6059443 344319..344777 1 NC_010473.1 hypothetical protein 344777 yaiI 6059443 yaiI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729294.1 344319 D 316385 CDS YP_001729295.1 170079975 6059445 344960..345484 1 NC_010473.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 345484 aroL 6059445 aroL Escherichia coli str. K-12 substr. DH10B shikimate kinase YP_001729295.1 344960 D 316385 CDS YP_001729296.1 170079976 6059449 345534..345725 1 NC_010473.1 hypothetical protein 345725 yaiA 6059449 yaiA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729296.1 345534 D 316385 CDS YP_001729297.1 170079977 6059454 345983..346660 1 NC_010473.1 hypothetical protein 346660 aroM 6059454 aroM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729297.1 345983 D 316385 CDS YP_001729298.1 170079978 6059457 346732..347016 1 NC_010473.1 hypothetical protein 347016 yaiE 6059457 yaiE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729298.1 346732 D 316385 CDS YP_001729299.1 170079979 6059462 347224..347505 1 NC_010473.1 hypothetical protein 347505 ykiA 6059462 ykiA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729299.1 347224 D 316385 CDS YP_001729300.1 170079980 6059464 complement(347663..348574) 1 NC_010473.1 Required for efficient pilin antigenic variation; recombination associated protein 348574 rdgC 6059464 rdgC Escherichia coli str. K-12 substr. DH10B recombination associated protein YP_001729300.1 347663 R 316385 CDS YP_001729301.1 170079981 6059467 348699..349607 1 NC_010473.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 349607 mak 6059467 mak Escherichia coli str. K-12 substr. DH10B fructokinase YP_001729301.1 348699 D 316385 CDS YP_001729302.1 170079982 6059134 complement(349852..351036) 1 NC_010473.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 351036 araJ 6059134 araJ Escherichia coli str. K-12 substr. DH10B MFS transport protein AraJ YP_001729302.1 349852 R 316385 CDS YP_001729303.1 170079983 6059475 complement(351162..354308) 1 NC_010473.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 354308 sbcC 6059475 sbcC Escherichia coli str. K-12 substr. DH10B exonuclease subunit SbcC YP_001729303.1 351162 R 316385 CDS YP_001729304.1 170079984 6059477 complement(354305..355507) 1 NC_010473.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 355507 sbcD 6059477 sbcD Escherichia coli str. K-12 substr. DH10B exonuclease subunit SbcD YP_001729304.1 354305 R 316385 CDS YP_001729305.1 170079985 6059481 355697..356386 1 NC_010473.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 356386 phoB 6059481 phoB Escherichia coli str. K-12 substr. DH10B transcriptional regulator PhoB YP_001729305.1 355697 D 316385 CDS YP_001729306.1 170079986 6059488 356444..357739 1 NC_010473.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 357739 phoR 6059488 phoR Escherichia coli str. K-12 substr. DH10B phosphate regulon sensor protein YP_001729306.1 356444 D 316385 CDS YP_001729307.1 170079987 6059495 358146..359465 1 NC_010473.1 branched chain amino acid ABC transporter 359465 brnQ 6059495 brnQ Escherichia coli str. K-12 substr. DH10B branched chain amino acid ABC transporter YP_001729307.1 358146 D 316385 CDS YP_001729308.1 170079988 6059496 359541..360914 1 NC_010473.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease 360914 proY 6059496 proY Escherichia coli str. K-12 substr. DH10B putative proline-specific permease YP_001729308.1 359541 D 316385 CDS YP_001729309.1 170079989 6059498 361070..362887 1 NC_010473.1 maltodextrin glucosidase 362887 malZ 6059498 malZ Escherichia coli str. K-12 substr. DH10B maltodextrin glucosidase YP_001729309.1 361070 D 316385 CDS YP_001729310.1 170079990 6059506 complement(362892..363473) 1 NC_010473.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 363473 acpH 6059506 acpH Escherichia coli str. K-12 substr. DH10B acyl carrier protein phosphodiesterase YP_001729310.1 362892 R 316385 CDS YP_001729311.1 170079991 6059509 363566..364636 1 NC_010473.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 364636 queA 6059509 queA Escherichia coli str. K-12 substr. DH10B S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001729311.1 363566 D 316385 CDS YP_001729312.1 170079992 6059510 364692..365819 1 NC_010473.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 365819 tgt 6059510 tgt Escherichia coli str. K-12 substr. DH10B queuine tRNA-ribosyltransferase YP_001729312.1 364692 D 316385 CDS YP_001729313.1 170079993 6060241 365842..366174 1 NC_010473.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 366174 yajC 6060241 yajC Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit YajC YP_001729313.1 365842 D 316385 CDS YP_001729314.1 170079994 6059511 366202..368049 1 NC_010473.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 368049 secD 6059511 secD Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit SecD YP_001729314.1 366202 D 316385 CDS YP_001729315.1 170079995 6059515 368060..369031 1 NC_010473.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 369031 secF 6059515 secF Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit SecF YP_001729315.1 368060 D 316385 CDS YP_001729316.1 170079996 6059517 369160..369507 1 NC_010473.1 hypothetical protein 369507 yajD 6059517 yajD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729316.1 369160 D 316385 CDS YP_001729317.1 170079997 6059520 complement(369684..370568) 1 NC_010473.1 nucleoside channel phage T6/colicin K receptor 370568 tsx 6059520 tsx Escherichia coli str. K-12 substr. DH10B nucleoside channel phage T6/colicin K receptor YP_001729317.1 369684 R 316385 CDS YP_001729318.1 170079998 6059524 complement(370867..371406) 1 NC_010473.1 hypothetical protein 371406 yajI 6059524 yajI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729318.1 370867 R 316385 CDS YP_001729319.1 170079999 6059529 371557..372006 1 NC_010473.1 transcriptional regulator NrdR 372006 nrdR 6059529 nrdR Escherichia coli str. K-12 substr. DH10B transcriptional regulator NrdR YP_001729319.1 371557 D 316385 CDS YP_001729320.1 170080000 6059530 372010..373113 1 NC_010473.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 373113 ribD 6059530 ribD Escherichia coli str. K-12 substr. DH10B bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_001729320.1 372010 D 316385 CDS YP_001729321.1 170080001 6059532 373202..373672 1 NC_010473.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 373672 ribH 6059532 ribH Escherichia coli str. K-12 substr. DH10B 6,7-dimethyl-8-ribityllumazine synthase YP_001729321.1 373202 D 316385 CDS YP_001729322.1 170080002 6059533 373692..374111 1 NC_010473.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 374111 nusB 6059533 nusB Escherichia coli str. K-12 substr. DH10B transcription antitermination protein NusB YP_001729322.1 373692 D 316385 CDS YP_001729323.1 170080003 6059535 374189..375166 1 NC_010473.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 375166 thiL 6059535 thiL Escherichia coli str. K-12 substr. DH10B thiamine monophosphate kinase YP_001729323.1 374189 D 316385 CDS YP_001729324.1 170080004 6059537 375144..375662 1 NC_010473.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 375662 pgpA 6059537 pgpA Escherichia coli str. K-12 substr. DH10B phosphatidylglycerophosphatase A YP_001729324.1 375144 D 316385 CDS YP_001729325.1 170080005 6059542 complement(375716..376690) 1 NC_010473.1 oxidoreductase, NAD(P)-binding 376690 yajO 6059542 yajO Escherichia coli str. K-12 substr. DH10B oxidoreductase, NAD(P)-binding YP_001729325.1 375716 R 316385 CDS YP_001729326.1 170080006 6059543 complement(376870..378732) 1 NC_010473.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 378732 dxs 6059543 dxs Escherichia coli str. K-12 substr. DH10B 1-deoxy-D-xylulose-5-phosphate synthase YP_001729326.1 376870 R 316385 CDS YP_001729327.1 170080007 6059545 complement(378757..379656) 1 NC_010473.1 geranyltranstransferase 379656 ispA 6059545 ispA Escherichia coli str. K-12 substr. DH10B geranyltranstransferase YP_001729327.1 378757 R 316385 CDS YP_001729328.1 170080008 6059548 complement(379656..379898) 1 NC_010473.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 379898 xseB 6059548 xseB Escherichia coli str. K-12 substr. DH10B exodeoxyribonuclease VII small subunit YP_001729328.1 379656 R 316385 CDS YP_001729329.1 170080009 6059550 380104..381552 1 NC_010473.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 381552 thiI 6059550 thiI Escherichia coli str. K-12 substr. DH10B thiamine biosynthesis protein ThiI YP_001729329.1 380104 D 316385 CDS YP_001729330.1 170080010 6059551 complement(381606..382196) 1 NC_010473.1 DJ-1 family protein 382196 yajL 6059551 yajL Escherichia coli str. K-12 substr. DH10B DJ-1 family protein YP_001729330.1 381606 R 316385 CDS YP_001729331.1 170080011 6059554 complement(382159..383070) 1 NC_010473.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 383070 panE 6059554 panE Escherichia coli str. K-12 substr. DH10B 2-dehydropantoate 2-reductase YP_001729331.1 382159 R 316385 CDS YP_001729332.1 170080012 6059555 383238..383729 1 NC_010473.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 383729 yajQ 6059555 yajQ Escherichia coli str. K-12 substr. DH10B putative nucleotide-binding protein YP_001729332.1 383238 D 316385 CDS YP_001729333.1 170080013 6059556 complement(383857..385221) 1 NC_010473.1 transporter 385221 yajR 6059556 yajR Escherichia coli str. K-12 substr. DH10B transporter YP_001729333.1 383857 R 316385 CDS YP_001729334.1 170080014 6059559 complement(385370..386260) 1 NC_010473.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 386260 cyoE 6059559 cyoE Escherichia coli str. K-12 substr. DH10B protoheme IX farnesyltransferase YP_001729334.1 385370 R 316385 CDS YP_001729335.1 170080015 6059561 complement(386272..386601) 1 NC_010473.1 cytochrome o ubiquinol oxidase subunit IV 386601 cyoD 6059561 cyoD Escherichia coli str. K-12 substr. DH10B cytochrome o ubiquinol oxidase subunit IV YP_001729335.1 386272 R 316385 CDS YP_001729336.1 170080016 6059562 complement(386601..387215) 1 NC_010473.1 cytochrome o ubiquinol oxidase subunit III 387215 cyoC 6059562 cyoC Escherichia coli str. K-12 substr. DH10B cytochrome o ubiquinol oxidase subunit III YP_001729336.1 386601 R 316385 CDS YP_001729337.1 170080017 6059565 complement(387205..389196) 1 NC_010473.1 cytochrome o ubiquinol oxidase subunit I 389196 cyoB 6059565 cyoB Escherichia coli str. K-12 substr. DH10B cytochrome o ubiquinol oxidase subunit I YP_001729337.1 387205 R 316385 CDS YP_001729338.1 170080018 6059567 complement(389218..390165) 1 NC_010473.1 cytochrome o ubiquinol oxidase subunit II 390165 cyoA 6059567 cyoA Escherichia coli str. K-12 substr. DH10B cytochrome o ubiquinol oxidase subunit II YP_001729338.1 389218 R 316385 CDS YP_001729339.1 170080019 6059568 complement(390625..392100) 1 NC_010473.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 392100 ampG 6059568 ampG Escherichia coli str. K-12 substr. DH10B muropeptide transporter YP_001729339.1 390625 R 316385 CDS YP_001729340.1 170080020 6059575 complement(392144..392722) 1 NC_010473.1 hypothetical protein 392722 yajG 6059575 yajG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729340.1 392144 R 316385 CDS YP_001729341.1 170080021 6059577 393027..393344 1 NC_010473.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 393344 bolA 6059577 bolA Escherichia coli str. K-12 substr. DH10B transcriptional regulator BolA YP_001729341.1 393027 D 316385 CDS YP_001729342.1 170080022 6059583 393688..394986 1 NC_010473.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 394986 tig 6059583 tig Escherichia coli str. K-12 substr. DH10B trigger factor YP_001729342.1 393688 D 316385 CDS YP_001729343.1 170080023 6059592 395232..395855 1 NC_010473.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 395855 clpP 6059592 clpP Escherichia coli str. K-12 substr. DH10B ATP-dependent Clp protease proteolytic subunit YP_001729343.1 395232 D 316385 CDS YP_001729344.1 170080024 6059595 395981..397255 1 NC_010473.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 397255 clpX 6059595 clpX Escherichia coli str. K-12 substr. DH10B ATP-dependent protease ATP-binding subunit ClpX YP_001729344.1 395981 D 316385 CDS YP_001729345.1 170080025 6059596 397443..399797 1 NC_010473.1 DNA-binding ATP-dependent protease La 399797 lon 6059596 lon Escherichia coli str. K-12 substr. DH10B DNA-binding ATP-dependent protease La YP_001729345.1 397443 D 316385 CDS YP_001729346.1 170080026 6059598 400006..400278 1 NC_010473.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 400278 hupB 6059598 hupB Escherichia coli str. K-12 substr. DH10B transcriptional regulator HU subunit beta YP_001729346.1 400006 D 316385 CDS YP_001729347.1 170080027 6059607 400470..402341 1 NC_010473.1 peptidyl-prolyl cis-trans isomerase 402341 ppiD 6059607 ppiD Escherichia coli str. K-12 substr. DH10B peptidyl-prolyl cis-trans isomerase YP_001729347.1 400470 D 316385 CDS YP_001729348.1 170080028 6059608 402492..402863 1 NC_010473.1 hypothetical protein 402863 ybaV 6059608 ybaV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729348.1 402492 D 316385 CDS YP_001729349.1 170080029 6059611 402957..403355 1 NC_010473.1 hypothetical protein 403355 ybaW 6059611 ybaW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729349.1 402957 D 316385 CDS YP_001729350.1 170080030 6059632 complement(403407..404102) 1 NC_010473.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 404102 queC 6059632 queC Escherichia coli str. K-12 substr. DH10B queuosine biosynthesis protein QueC YP_001729350.1 403407 R 316385 CDS YP_001729351.1 170080031 6059633 complement(404167..405867) 1 NC_010473.1 ABC transporter substrate-binding protein 405867 ybaE 6059633 ybaE Escherichia coli str. K-12 substr. DH10B ABC transporter substrate-binding protein YP_001729351.1 404167 R 316385 CDS YP_001729352.1 170080032 6059635 405967..406785 1 NC_010473.1 thiamin pyrimidine pyrophosphate hydrolase 406785 cof 6059635 cof Escherichia coli str. K-12 substr. DH10B thiamin pyrimidine pyrophosphate hydrolase YP_001729352.1 405967 D 316385 CDS YP_001729353.1 170080033 6059649 406938..407396 1 NC_010473.1 DNA-binding transcriptional regulator 407396 ybaO 6059649 ybaO Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729353.1 406938 D 316385 CDS YP_001729354.1 170080034 6059650 407426..409198 1 NC_010473.1 putative multidrug transporter membrane\ATP-binding components 409198 mdlA 6059650 mdlA Escherichia coli str. K-12 substr. DH10B putative multidrug transporter membrane\ATP-binding components YP_001729354.1 407426 D 316385 CDS YP_001729355.1 170080035 6059653 409191..410972 1 NC_010473.1 putative multidrug transporter membrane\ATP-binding components 410972 mdlB 6059653 mdlB Escherichia coli str. K-12 substr. DH10B putative multidrug transporter membrane\ATP-binding components YP_001729355.1 409191 D 316385 CDS YP_001729356.1 170080036 6059664 411153..411491 1 NC_010473.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 411491 glnK 6059664 glnK Escherichia coli str. K-12 substr. DH10B nitrogen regulatory protein P-II 2 YP_001729356.1 411153 D 316385 CDS YP_001729357.1 170080037 6059668 411521..412807 1 NC_010473.1 ammonium transporter 412807 amtB 6059668 amtB Escherichia coli str. K-12 substr. DH10B ammonium transporter YP_001729357.1 411521 D 316385 CDS YP_001729358.1 170080038 6059671 complement(412856..413716) 1 NC_010473.1 acyl-CoA thioesterase II 413716 tesB 6059671 tesB Escherichia coli str. K-12 substr. DH10B acyl-CoA thioesterase II YP_001729358.1 412856 R 316385 CDS YP_001729359.1 170080039 6059672 413934..414506 1 NC_010473.1 outer membrane lipoprotein 414506 ybaY 6059672 ybaY Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein YP_001729359.1 413934 D 316385 CDS YP_001729360.1 170080040 6059674 complement(414537..414926) 1 NC_010473.1 methyltransferase 414926 ybaZ 6059674 ybaZ Escherichia coli str. K-12 substr. DH10B methyltransferase YP_001729360.1 414537 R 316385 CDS YP_001729361.1 170080041 6061734 415227..415580 1 NC_010473.1 hypothetical protein 415580 ybaA 6061734 ybaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729361.1 415227 D 316385 CDS YP_001729362.1 170080042 6059678 complement(415622..417172) 1 NC_010473.1 inner membrane protein 417172 ylaB 6059678 ylaB Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729362.1 415622 R 316385 CDS YP_001729363.1 170080043 6059681 complement(417336..417806) 1 NC_010473.1 inner membrane protein 417806 ylaC 6059681 ylaC Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729363.1 417336 R 316385 CDS YP_001729364.1 170080044 6059684 complement(417922..418473) 1 NC_010473.1 maltose O-acetyltransferase 418473 maa 6059684 maa Escherichia coli str. K-12 substr. DH10B maltose O-acetyltransferase YP_001729364.1 417922 R 316385 CDS YP_001729365.1 170080045 6059976 complement(418645..418863) 1 NC_010473.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 418863 hha 6059976 hha Escherichia coli str. K-12 substr. DH10B hemolysin expression-modulating protein YP_001729365.1 418645 R 316385 CDS YP_001729366.1 170080046 6059688 complement(418889..419263) 1 NC_010473.1 hypothetical protein 419263 ybaJ 6059688 ybaJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729366.1 418889 R 316385 CDS YP_001729367.1 170080047 6059690 complement(419809..422958) 1 NC_010473.1 multidrug efflux system protein 422958 acrB 6059690 acrB Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein YP_001729367.1 419809 R 316385 CDS YP_001729368.1 170080048 6059692 complement(422981..424174) 1 NC_010473.1 multidrug efflux system 424174 acrA 6059692 acrA Escherichia coli str. K-12 substr. DH10B multidrug efflux system YP_001729368.1 422981 R 316385 CDS YP_001729369.1 170080049 6059695 424316..424963 1 NC_010473.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 424963 acrR 6059695 acrR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor AcrR YP_001729369.1 424316 D 316385 CDS YP_001729370.1 170080050 6059697 425091..428453 1 NC_010473.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 428453 kefA 6059697 kefA Escherichia coli str. K-12 substr. DH10B potassium efflux protein KefA YP_001729370.1 425091 D 316385 CDS YP_001729371.1 170080051 6059700 complement(428665..428826) 1 NC_010473.1 hypothetical protein 428826 ybaM 6059700 ybaM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729371.1 428665 R 316385 CDS YP_001729372.1 170080052 6059708 complement(428840..429367) 1 NC_010473.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 429367 priC 6059708 priC Escherichia coli str. K-12 substr. DH10B primosomal replication protein N'' YP_001729372.1 428840 R 316385 CDS YP_001729373.1 170080053 6059719 429437..429814 1 NC_010473.1 hypothetical protein 429814 ybaN 6059719 ybaN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729373.1 429437 D 316385 CDS YP_001729374.1 170080054 6059725 429967..430518 1 NC_010473.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 430518 apt 6059725 apt Escherichia coli str. K-12 substr. DH10B adenine phosphoribosyltransferase YP_001729374.1 429967 D 316385 CDS YP_001729375.1 170080055 6059726 430647..432578 1 NC_010473.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 432578 dnaX 6059726 dnaX Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunits gamma and tau YP_001729375.1 430647 D 316385 CDS YP_001729376.1 170080056 6059732 432631..432960 1 NC_010473.1 hypothetical protein 432960 ybaB 6059732 ybaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729376.1 432631 D 316385 CDS YP_001729377.1 170080057 6059736 432960..433565 1 NC_010473.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 433565 recR 6059736 recR Escherichia coli str. K-12 substr. DH10B recombination protein RecR YP_001729377.1 432960 D 316385 CDS YP_001729378.1 170080058 6059744 433675..435549 1 NC_010473.1 molecular chaperone; heat shock protein 90 435549 htpG 6059744 htpG Escherichia coli str. K-12 substr. DH10B heat shock protein 90 YP_001729378.1 433675 D 316385 CDS YP_001729379.1 170080059 6059750 435730..436374 1 NC_010473.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 436374 adk 6059750 adk Escherichia coli str. K-12 substr. DH10B adenylate kinase YP_001729379.1 435730 D 316385 CDS YP_001729380.1 170080060 6059765 436610..437572 1 NC_010473.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 437572 hemH 6059765 hemH Escherichia coli str. K-12 substr. DH10B ferrochelatase YP_001729380.1 436610 D 316385 CDS YP_001729381.1 170080061 6059767 complement(437569..438528) 1 NC_010473.1 acetyl esterase 438528 aes 6059767 aes Escherichia coli str. K-12 substr. DH10B acetyl esterase YP_001729381.1 437569 R 316385 CDS YP_001729382.1 170080062 6059770 438680..439984 1 NC_010473.1 inosine/guanosine kinase 439984 gsk 6059770 gsk Escherichia coli str. K-12 substr. DH10B inosine/guanosine kinase YP_001729382.1 438680 D 316385 CDS YP_001729383.1 170080063 6059774 complement(440117..441793) 1 NC_010473.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein 441793 ybaL 6059774 ybaL Escherichia coli str. K-12 substr. DH10B putative cation:proton antiport protein YP_001729383.1 440117 R 316385 CDS YP_001729384.1 170080064 6059782 complement(442031..443251) 1 NC_010473.1 fosmidomycin efflux system 443251 fsr 6059782 fsr Escherichia coli str. K-12 substr. DH10B fosmidomycin efflux system YP_001729384.1 442031 R 316385 CDS YP_001729385.1 170080065 6059784 443469..445121 1 NC_010473.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 445121 ushA 6059784 ushA Escherichia coli str. K-12 substr. DH10B bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_001729385.1 443469 D 316385 CDS YP_001729386.1 170080066 6062380 complement(445158..445637) 1 NC_010473.1 hypothetical protein 445637 ybaK 6062380 ybaK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729386.1 445158 R 316385 CDS YP_001729387.1 170080067 6058803 complement(445841..446635) 1 NC_010473.1 hypothetical protein 446635 ybaP 6058803 ybaP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729387.1 445841 R 316385 CDS YP_001729388.1 170080068 6059796 446773..447114 1 NC_010473.1 DNA-binding transcriptional regulator 447114 ybaQ 6059796 ybaQ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729388.1 446773 D 316385 CDS YP_001729389.1 170080069 6059797 complement(447430..449934) 1 NC_010473.1 copper exporting ATPase 449934 copA 6059797 copA Escherichia coli str. K-12 substr. DH10B copper exporting ATPase YP_001729389.1 447430 R 316385 CDS YP_001729390.1 170080070 6059798 450196..451128 1 NC_010473.1 catalyzes the formation of glutamate from glutamine; glutaminase 451128 ybaS 6059798 ybaS Escherichia coli str. K-12 substr. DH10B glutaminase YP_001729390.1 450196 D 316385 CDS YP_001729391.1 170080071 6059799 451131..452423 1 NC_010473.1 transporter 452423 ybaT 6059799 ybaT Escherichia coli str. K-12 substr. DH10B transporter YP_001729391.1 451131 D 316385 CDS YP_001729392.1 170080072 6059803 452548..452955 1 NC_010473.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 452955 cueR 6059803 cueR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator CueR YP_001729392.1 452548 D 316385 CDS YP_001729393.1 170080073 6059805 complement(452956..453411) 1 NC_010473.1 inner membrane protein 453411 ybbJ 6059805 ybbJ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729393.1 452956 R 316385 CDS YP_001729394.1 170080074 6059811 complement(453411..454328) 1 NC_010473.1 protease, membrane anchored 454328 qmcA 6059811 qmcA Escherichia coli str. K-12 substr. DH10B protease, membrane anchored YP_001729394.1 453411 R 316385 CDS YP_001729395.1 170080075 6059812 454474..455151 1 NC_010473.1 putative ABC transporter ATP-binding protein YbbL 455151 ybbL 6059812 ybbL Escherichia coli str. K-12 substr. DH10B putative ABC transporter ATP-binding protein YbbL YP_001729395.1 454474 D 316385 CDS YP_001729396.1 170080076 6059813 455138..455917 1 NC_010473.1 inner membrane protein 455917 ybbM 6059813 ybbM Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729396.1 455138 D 316385 CDS YP_001729397.1 170080077 6059818 complement(455980..456834) 1 NC_010473.1 thioredoxin domain-containing protein 456834 ybbN 6059818 ybbN Escherichia coli str. K-12 substr. DH10B thioredoxin domain-containing protein YP_001729397.1 455980 R 316385 CDS YP_001729398.1 170080078 6059819 complement(456895..457704) 1 NC_010473.1 short chain dehydrogenase 457704 ybbO 6059819 ybbO Escherichia coli str. K-12 substr. DH10B short chain dehydrogenase YP_001729398.1 456895 R 316385 CDS YP_001729399.1 170080079 6059820 complement(457694..458320) 1 NC_010473.1 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 458320 tesA 6059820 tesA Escherichia coli str. K-12 substr. DH10B multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_001729399.1 457694 R 316385 CDS YP_001729400.1 170080080 6059822 458288..458974 1 NC_010473.1 putative ABC transporter ATP-binding protein YbbA 458974 ybbA 6059822 ybbA Escherichia coli str. K-12 substr. DH10B putative ABC transporter ATP-binding protein YbbA YP_001729400.1 458288 D 316385 CDS YP_001729401.1 170080081 6059824 458971..461385 1 NC_010473.1 inner membrane protein 461385 ybbP 6059824 ybbP Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729401.1 458971 D 316385 CDS YP_001729402.1 170080082 6059617 461816..466096 1 NC_010473.1 rhsD element protein 466096 rhsD 6059617 rhsD Escherichia coli str. K-12 substr. DH10B rhsD element protein YP_001729402.1 461816 D 316385 CDS YP_001729403.1 170080083 6059619 466136..466504 1 NC_010473.1 hypothetical protein 466504 ybbC 6059619 ybbC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729403.1 466136 D 316385 CDS YP_001729404.1 170080084 6059624 466504..467214 1 NC_010473.1 protein, rhs-like protein 467214 ylbH 6059624 ylbH Escherichia coli str. K-12 substr. DH10B protein, rhs-like protein YP_001729404.1 466504 D 316385 CDS YP_001729405.1 170080085 6059334 complement(468200..468571) 1 NC_010473.1 DNA-binding transcriptional regulator 468571 ylbG 6059334 ylbG Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729405.1 468200 R 316385 CDS YP_001729406.1 170080086 6059628 complement(468687..469781) 1 NC_010473.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 469781 ybbB 6059628 ybbB Escherichia coli str. K-12 substr. DH10B tRNA 2-selenouridine synthase YP_001729406.1 468687 R 316385 CDS YP_001729407.1 170080087 6059630 complement(469850..470776) 1 NC_010473.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 470776 allS 6059630 allS Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator AllS YP_001729407.1 469850 R 316385 CDS YP_001729408.1 170080088 6059827 471006..471488 1 NC_010473.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 471488 allA 6059827 allA Escherichia coli str. K-12 substr. DH10B ureidoglycolate hydrolase YP_001729408.1 471006 D 316385 CDS YP_001729409.1 170080089 6059851 471566..472381 1 NC_010473.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 472381 allR 6059851 allR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor AllR YP_001729409.1 471566 D 316385 CDS YP_001729410.1 170080090 6059868 472471..474252 1 NC_010473.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 474252 gcl 6059868 gcl Escherichia coli str. K-12 substr. DH10B glyoxylate carboligase YP_001729410.1 472471 D 316385 CDS YP_001729411.1 170080091 6059884 474265..475041 1 NC_010473.1 hydroxypyruvate isomerase 475041 hyi 6059884 hyi Escherichia coli str. K-12 substr. DH10B hydroxypyruvate isomerase YP_001729411.1 474265 D 316385 CDS YP_001729412.1 170080092 6059888 475141..476019 1 NC_010473.1 tartronate semialdehyde reductase, NADH-dependent 476019 glxR 6059888 glxR Escherichia coli str. K-12 substr. DH10B tartronate semialdehyde reductase, NADH-dependent YP_001729412.1 475141 D 316385 CDS YP_001729413.1 170080093 6059894 476051..476329 1 NC_010473.1 hypothetical protein 476329 ybbV 6059894 ybbV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729413.1 476051 D 316385 CDS YP_001729414.1 170080094 6059898 476188..477642 1 NC_010473.1 allantoin permease 477642 ybbW 6059898 ybbW Escherichia coli str. K-12 substr. DH10B allantoin permease YP_001729414.1 476188 D 316385 CDS YP_001729415.1 170080095 6059904 477702..479063 1 NC_010473.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 479063 allB 6059904 allB Escherichia coli str. K-12 substr. DH10B allantoinase YP_001729415.1 477702 D 316385 CDS YP_001729416.1 170080096 6059907 479120..480421 1 NC_010473.1 putative purine permease YbbY 480421 ybbY 6059907 ybbY Escherichia coli str. K-12 substr. DH10B putative purine permease YbbY YP_001729416.1 479120 D 316385 CDS YP_001729417.1 170080097 6059931 480443..481588 1 NC_010473.1 glycerate kinase 481588 glxK 6059931 glxK Escherichia coli str. K-12 substr. DH10B glycerate kinase YP_001729417.1 480443 D 316385 CDS YP_001729418.1 170080098 6059936 complement(481816..482601) 1 NC_010473.1 hypothetical protein 482601 ylbA 6059936 ylbA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729418.1 481816 R 316385 CDS YP_001729419.1 170080099 6059940 complement(482612..483847) 1 NC_010473.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 483847 allC 6059940 allC Escherichia coli str. K-12 substr. DH10B allantoate amidohydrolase YP_001729419.1 482612 R 316385 CDS YP_001729420.1 170080100 6059947 complement(483869..484918) 1 NC_010473.1 ureidoglycolate dehydrogenase 484918 allD 6059947 allD Escherichia coli str. K-12 substr. DH10B ureidoglycolate dehydrogenase YP_001729420.1 483869 R 316385 CDS YP_001729421.1 170080101 6059980 485235..486902 1 NC_010473.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 486902 fdrA 6059980 fdrA Escherichia coli str. K-12 substr. DH10B membrane protein FdrA YP_001729421.1 485235 D 316385 CDS YP_001729422.1 170080102 6060012 486912..488171 1 NC_010473.1 DH10B lacks the frameshift in codon 85 that disrupts ylbE in both MG1655 and W3110; hypothetical protein 488171 ylbE 6060012 ylbE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729422.1 486912 D 316385 CDS YP_001729423.1 170080103 6058653 488182..488997 1 NC_010473.1 hypothetical protein 488997 ylbF 6058653 ylbF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729423.1 488182 D 316385 CDS YP_001729424.1 170080104 6060016 488994..489887 1 NC_010473.1 carbamate kinase 489887 ybcF 6060016 ybcF Escherichia coli str. K-12 substr. DH10B carbamate kinase YP_001729424.1 488994 D 316385 CDS YP_001729425.1 170080105 6060032 complement(490082..491149) 1 NC_010473.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 491149 purK 6060032 purK Escherichia coli str. K-12 substr. DH10B phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001729425.1 490082 R 316385 CDS YP_001729426.1 170080106 6060049 complement(491146..491655) 1 NC_010473.1 N5-carboxyaminoimidazole ribonucleotide mutase 491655 purE 6060049 purE Escherichia coli str. K-12 substr. DH10B N5-carboxyaminoimidazole ribonucleotide mutase YP_001729426.1 491146 R 316385 CDS YP_001729427.1 170080107 6060059 complement(491773..492495) 1 NC_010473.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 492495 lpxH 6060059 lpxH Escherichia coli str. K-12 substr. DH10B UDP-2,3-diacylglucosamine hydrolase YP_001729427.1 491773 R 316385 CDS YP_001729428.1 170080108 6060071 complement(492498..492992) 1 NC_010473.1 peptidyl-prolyl cis-trans isomerase B 492992 ppiB 6060071 ppiB Escherichia coli str. K-12 substr. DH10B peptidyl-prolyl cis-trans isomerase B YP_001729428.1 492498 R 316385 CDS YP_001729429.1 170080109 6058949 493166..494551 1 NC_010473.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 494551 cysS 6058949 cysS Escherichia coli str. K-12 substr. DH10B cysteinyl-tRNA synthetase YP_001729429.1 493166 D 316385 CDS YP_001729430.1 170080110 6060076 complement(494587..495108) 1 NC_010473.1 inner membrane protein 495108 ybcI 6060076 ybcI Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729430.1 494587 R 316385 CDS YP_001729431.1 170080111 6060077 complement(495216..495428) 1 NC_010473.1 hypothetical protein 495428 ybcJ 6060077 ybcJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729431.1 495216 R 316385 CDS YP_001729432.1 170080112 6060087 complement(495430..496296) 1 NC_010473.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 496296 folD 6060087 folD Escherichia coli str. K-12 substr. DH10B bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001729432.1 495430 R 316385 CDS YP_001729433.1 170080113 6060090 496767..497309 1 NC_010473.1 fimbrial-like adhesin protein 497309 sfmA 6060090 sfmA Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729433.1 496767 D 316385 CDS YP_001729434.1 170080114 6060101 497529..498221 1 NC_010473.1 pilin chaperone, periplasmic 498221 sfmC 6060101 sfmC Escherichia coli str. K-12 substr. DH10B pilin chaperone, periplasmic YP_001729434.1 497529 D 316385 CDS YP_001729435.1 170080115 6060103 498252..500855 1 NC_010473.1 outer membrane export usher protein 500855 sfmD 6060103 sfmD Escherichia coli str. K-12 substr. DH10B outer membrane export usher protein YP_001729435.1 498252 D 316385 CDS YP_001729436.1 170080116 6060110 500891..501874 1 NC_010473.1 fimbrial-like adhesin protein 501874 sfmH 6060110 sfmH Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729436.1 500891 D 316385 CDS YP_001729437.1 170080117 6060117 501885..502400 1 NC_010473.1 putative fimbrial protein 502400 sfmF 6060117 sfmF Escherichia coli str. K-12 substr. DH10B putative fimbrial protein YP_001729437.1 501885 D 316385 CDS YP_001729438.1 170080118 6060120 complement(502403..503035) 1 NC_010473.1 activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 503035 fimZ 6060120 fimZ Escherichia coli str. K-12 substr. DH10B transcriptional regulator FimZ YP_001729438.1 502403 R 316385 CDS YP_001729439.1 170080119 6058724 complement(503370..504533) 1 NC_010473.1 DLP12 prophage; integrase 504533 intD 6058724 intD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; integrase YP_001729439.1 503370 R 316385 CDS YP_001729440.1 170080120 6060122 complement(504653..504916) 1 NC_010473.1 DLP12 prophage; exonuclease 504916 ybcC 6060122 ybcC Escherichia coli str. K-12 substr. DH10B DLP12 prophage; exonuclease YP_001729440.1 504653 R 316385 CDS YP_001729441.1 170080121 6058968 505388..505696 1 NC_010473.1 DLP12 prophage; IS3 element protein InsE 505696 insE-3 6058968 insE-3 Escherichia coli str. K-12 substr. DH10B DLP12 prophage; IS3 element protein InsE YP_001729441.1 505388 D 316385 CDS YP_001729442.1 170080122 6060137 505693..506559 1 NC_010473.1 DLP12 prophage; IS3 element protein InsF 506559 insF-3 6060137 insF-3 Escherichia coli str. K-12 substr. DH10B DLP12 prophage; IS3 element protein InsF YP_001729442.1 505693 D 316385 CDS YP_001729443.1 170080123 6060175 506617..506802 1 NC_010473.1 DLP12 prophage; hypothetical protein 506802 renD 6060175 renD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; hypothetical protein YP_001729443.1 506617 D 316385 CDS YP_001729444.1 170080124 6060189 506870..507202 1 NC_010473.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 507202 emrE 6060189 emrE Escherichia coli str. K-12 substr. DH10B multidrug efflux protein YP_001729444.1 506870 D 316385 CDS YP_001729445.1 170080125 6060193 507457..508983 1 NC_010473.1 DLP12 prophage; recombinase 508983 ybcK 6060193 ybcK Escherichia coli str. K-12 substr. DH10B DLP12 prophage; recombinase YP_001729445.1 507457 D 316385 CDS YP_001729446.1 170080126 6060200 509448..509999 1 NC_010473.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; putative kinase inhibitor 509999 ybcL 6060200 ybcL Escherichia coli str. K-12 substr. DH10B putative kinase inhibitor YP_001729446.1 509448 D 316385 CDS YP_001729447.1 170080127 6060206 510009..510806 1 NC_010473.1 DLP12 prophage; DNA-binding transcriptional regulator 510806 ybcM 6060206 ybcM Escherichia coli str. K-12 substr. DH10B DLP12 prophage; DNA-binding transcriptional regulator YP_001729447.1 510009 D 316385 CDS YP_001729448.1 170080128 6060210 511021..511476 1 NC_010473.1 DLP12 prophage; hypothetical protein 511476 ybcN 6060210 ybcN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729448.1 511021 D 316385 CDS YP_001729449.1 170080129 6060221 511476..511646 1 NC_010473.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 511646 ninE 6060221 ninE Escherichia coli str. K-12 substr. DH10B prophage protein NinE YP_001729449.1 511476 D 316385 CDS YP_001729450.1 170080130 6062415 511639..511929 1 NC_010473.1 DLP12 prophage; hypothetical protein 511929 ybcO 6062415 ybcO Escherichia coli str. K-12 substr. DH10B DLP12 prophage; hypothetical protein YP_001729450.1 511639 D 316385 CDS YP_001729451.1 170080131 6060232 511926..512288 1 NC_010473.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 512288 rusA 6060232 rusA Escherichia coli str. K-12 substr. DH10B endodeoxyribonuclease RUS YP_001729451.1 511926 D 316385 CDS YP_001729452.1 170080132 6060238 512285..512425 1 NC_010473.1 DLP12 prophage; hypothetical protein 512425 ylcG 6060238 ylcG Escherichia coli str. K-12 substr. DH10B DLP12 prophage; hypothetical protein YP_001729452.1 512285 D 316385 CDS YP_001729453.1 170080133 6060239 512511..512894 1 NC_010473.1 DLP12 prophage; antitermination protein 512894 ybcQ 6060239 ybcQ Escherichia coli str. K-12 substr. DH10B DLP12 prophage; antitermination protein YP_001729453.1 512511 D 316385 CDS YP_001729454.1 170080134 6059499 complement(513292..514308) 1 NC_010473.1 DLP12 prophage; IS5 transposase and trans-activator 514308 insH-2 6059499 insH-2 Escherichia coli str. K-12 substr. DH10B DLP12 prophage; IS5 transposase and trans-activator YP_001729454.1 513292 R 316385 CDS YP_001729455.1 170080135 6060252 515953..516168 1 NC_010473.1 DLP12 prophage; phage lysis protein 516168 essD 6060252 essD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; phage lysis protein YP_001729455.1 515953 D 316385 CDS YP_001729456.1 170080136 6060258 516168..516665 1 NC_010473.1 DLP12 prophage; lysozyme 516665 ybcS 6060258 ybcS Escherichia coli str. K-12 substr. DH10B DLP12 prophage; lysozyme YP_001729456.1 516168 D 316385 CDS YP_001729457.1 170080137 6060259 516662..517123 1 NC_010473.1 DLP12 prophage; murein endopeptidase 517123 rzpD 6060259 rzpD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; murein endopeptidase YP_001729457.1 516662 D 316385 CDS YP_001729458.1 170080138 6060266 516882..517064 1 NC_010473.1 DLP12 prophage; lipoprotein 517064 rzoD 6060266 rzoD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; lipoprotein YP_001729458.1 516882 D 316385 CDS YP_001729459.1 170080139 6060273 complement(517155..517448) 1 NC_010473.1 DLP12 prophage; lipoprotein 517448 borD 6060273 borD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; lipoprotein YP_001729459.1 517155 R 316385 CDS YP_001729460.1 170080140 6060282 complement(517739..518149) 1 NC_010473.1 DLP12 prophage; hypothetical protein 518149 ybcV 6060282 ybcV Escherichia coli str. K-12 substr. DH10B DLP12 prophage; hypothetical protein YP_001729460.1 517739 R 316385 CDS YP_001729461.1 170080141 6060296 518435..518641 1 NC_010473.1 DLP12 prophage; hypothetical protein 518641 ybcW 6060296 ybcW Escherichia coli str. K-12 substr. DH10B DLP12 prophage; hypothetical protein YP_001729461.1 518435 D 316385 CDS YP_001729462.1 170080142 6060303 519389..519934 1 NC_010473.1 DLP12 prophage; DNA packaging protein 519934 nohB 6060303 nohB Escherichia coli str. K-12 substr. DH10B DLP12 prophage; DNA packaging protein YP_001729462.1 519389 D 316385 CDS YP_001729463.1 170080143 6060852 522236..522985 1 NC_010473.1 DLP12 prophage; DNA-binding transcriptional activator 522985 appY 6060852 appY Escherichia coli str. K-12 substr. DH10B DLP12 prophage; DNA-binding transcriptional activator YP_001729463.1 522236 D 316385 CDS YP_001729464.1 170080144 6060305 complement(523235..524188) 1 NC_010473.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 524188 ompT 6060305 ompT Escherichia coli str. K-12 substr. DH10B outer membrane protease YP_001729464.1 523235 R 316385 CDS YP_001729465.1 170080145 6060306 complement(524702..525463) 1 NC_010473.1 DNA-binding transcriptional activator of porin biosynthesis 525463 envY 6060306 envY Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator of porin biosynthesis YP_001729465.1 524702 R 316385 CDS YP_001729466.1 170080146 6059964 complement(525646..526536) 1 NC_010473.1 hypothetical protein 526536 ybcH 6059964 ybcH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729466.1 525646 R 316385 CDS YP_001729467.1 170080147 6060307 complement(526537..529509) 1 NC_010473.1 bacteriophage N4 receptor, outer membrane subunit 529509 nfrA 6060307 nfrA Escherichia coli str. K-12 substr. DH10B bacteriophage N4 receptor, outer membrane subunit YP_001729467.1 526537 R 316385 CDS YP_001729468.1 170080148 6060321 complement(529496..531733) 1 NC_010473.1 bacteriophage N4 adsorption protein B 531733 nfrB 6060321 nfrB Escherichia coli str. K-12 substr. DH10B bacteriophage N4 adsorption protein B YP_001729468.1 529496 R 316385 CDS YP_001729469.1 170080149 6060324 complement(531883..533325) 1 NC_010473.1 sensor kinase CusS 533325 cusS 6060324 cusS Escherichia coli str. K-12 substr. DH10B sensor kinase CusS YP_001729469.1 531883 R 316385 CDS YP_001729470.1 170080150 6060325 complement(533315..533998) 1 NC_010473.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 533998 cusR 6060325 cusR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator CusR YP_001729470.1 533315 R 316385 CDS YP_001729471.1 170080151 6060327 534155..535528 1 NC_010473.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 535528 cusC 6060327 cusC Escherichia coli str. K-12 substr. DH10B copper/silver efflux system outer membrane protein CusC YP_001729471.1 534155 D 316385 CDS YP_001729472.1 170080152 6060329 535686..536018 1 NC_010473.1 copper-binding protein 536018 cusF 6060329 cusF Escherichia coli str. K-12 substr. DH10B copper-binding protein YP_001729472.1 535686 D 316385 CDS YP_001729473.1 170080153 6060339 536034..537257 1 NC_010473.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 537257 cusB 6060339 cusB Escherichia coli str. K-12 substr. DH10B copper/silver efflux system membrane fusion protein CusB YP_001729473.1 536034 D 316385 CDS YP_001729474.1 170080154 6060345 537269..540412 1 NC_010473.1 copper/silver efflux system, membrane component 540412 cusA 6060345 cusA Escherichia coli str. K-12 substr. DH10B copper/silver efflux system, membrane component YP_001729474.1 537269 D 316385 CDS YP_001729475.1 170080155 6060346 540514..541890 1 NC_010473.1 phenylalanine transporter 541890 pheP 6060346 pheP Escherichia coli str. K-12 substr. DH10B phenylalanine transporter YP_001729475.1 540514 D 316385 CDS YP_001729476.1 170080156 6060356 complement(541971..543218) 1 NC_010473.1 mechanosensitive channel 543218 ybdG 6060356 ybdG Escherichia coli str. K-12 substr. DH10B mechanosensitive channel YP_001729476.1 541971 R 316385 CDS YP_001729477.1 170080157 6060362 complement(543326..543979) 1 NC_010473.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 543979 nfnB 6060362 nfnB Escherichia coli str. K-12 substr. DH10B dihydropteridine reductase YP_001729477.1 543326 R 316385 CDS YP_001729478.1 170080158 6060370 complement(544073..544441) 1 NC_010473.1 hypothetical protein 544441 ybdF 6060370 ybdF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729478.1 544073 R 316385 CDS YP_001729479.1 170080159 6060382 complement(544506..544754) 1 NC_010473.1 inner membrane protein 544754 ybdJ 6060382 ybdJ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729479.1 544506 R 316385 CDS YP_001729480.1 170080160 6060383 complement(544820..545938) 1 NC_010473.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 545938 ybdK 6060383 ybdK Escherichia coli str. K-12 substr. DH10B carboxylate-amine ligase YP_001729480.1 544820 R 316385 CDS YP_001729481.1 170080161 6060387 546391..546543 1 NC_010473.1 toxic polypeptide, small 546543 hokE 6060387 hokE Escherichia coli str. K-12 substr. DH10B toxic polypeptide, small YP_001729481.1 546391 D 316385 CDS YP_001729482.1 170080162 6060394 546620..547732 1 NC_010473.1 IS186/IS421 transposase 547732 insL-2 6060394 insL-2 Escherichia coli str. K-12 substr. DH10B IS186/IS421 transposase YP_001729482.1 546620 D 316385 CDS YP_001729483.1 170080163 6060408 complement(548014..548643) 1 NC_010473.1 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 548643 entD 6060408 entD Escherichia coli str. K-12 substr. DH10B phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_001729483.1 548014 R 316385 CDS YP_001729484.1 170080164 6060409 complement(548809..551049) 1 NC_010473.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 551049 fepA 6060409 fepA Escherichia coli str. K-12 substr. DH10B outer membrane receptor FepA YP_001729484.1 548809 R 316385 CDS YP_001729485.1 170080165 6060423 551370..552494 1 NC_010473.1 enterobactin/ferric enterobactin esterase 552494 fes 6060423 fes Escherichia coli str. K-12 substr. DH10B enterobactin/ferric enterobactin esterase YP_001729485.1 551370 D 316385 CDS YP_001729486.1 170080166 6060424 552497..552715 1 NC_010473.1 hypothetical protein 552715 ybdZ 6060424 ybdZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729486.1 552497 D 316385 CDS YP_001729487.1 170080167 6060427 552712..556593 1 NC_010473.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 556593 entF 6060427 entF Escherichia coli str. K-12 substr. DH10B enterobactin synthase subunit F YP_001729487.1 552712 D 316385 CDS YP_001729488.1 170080168 6060429 556809..557942 1 NC_010473.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 557942 fepE 6060429 fepE Escherichia coli str. K-12 substr. DH10B ferric enterobactin transport protein FepE YP_001729488.1 556809 D 316385 CDS YP_001729489.1 170080169 6060434 complement(557939..558754) 1 NC_010473.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 558754 fepC 6060434 fepC Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter ATP-binding protein YP_001729489.1 557939 R 316385 CDS YP_001729490.1 170080170 6060454 complement(558751..559743) 1 NC_010473.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 559743 fepG 6060454 fepG Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter permease YP_001729490.1 558751 R 316385 CDS YP_001729491.1 170080171 6060458 complement(559740..560744) 1 NC_010473.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 560744 fepD 6060458 fepD Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter membrane protein YP_001729491.1 559740 R 316385 CDS YP_001729492.1 170080172 6058761 560855..562105 1 NC_010473.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 562105 entS 6058761 entS Escherichia coli str. K-12 substr. DH10B enterobactin exporter EntS YP_001729492.1 560855 D 316385 CDS YP_001729493.1 170080173 6059043 complement(562109..563065) 1 NC_010473.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 563065 fepB 6059043 fepB Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter periplasmic binding protein YP_001729493.1 562109 R 316385 CDS YP_001729494.1 170080174 6060467 563440..564615 1 NC_010473.1 isochorismate synthase 1 564615 entC 6060467 entC Escherichia coli str. K-12 substr. DH10B isochorismate synthase 1 YP_001729494.1 563440 D 316385 CDS YP_001729495.1 170080175 6060494 564625..566235 1 NC_010473.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 566235 entE 6060494 entE Escherichia coli str. K-12 substr. DH10B enterobactin synthase subunit E YP_001729495.1 564625 D 316385 CDS YP_001729496.1 170080176 6060506 566249..567106 1 NC_010473.1 isochorismatase 567106 entB 6060506 entB Escherichia coli str. K-12 substr. DH10B isochorismatase YP_001729496.1 566249 D 316385 CDS YP_001729497.1 170080177 6060507 567106..567852 1 NC_010473.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 567852 entA 6060507 entA Escherichia coli str. K-12 substr. DH10B 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_001729497.1 567106 D 316385 CDS YP_001729498.1 170080178 6060512 567855..568268 1 NC_010473.1 hypothetical protein 568268 ybdB 6060512 ybdB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729498.1 567855 D 316385 CDS YP_001729499.1 170080179 6060515 568449..570554 1 NC_010473.1 carbon starvation protein 570554 cstA 6060515 cstA Escherichia coli str. K-12 substr. DH10B carbon starvation protein YP_001729499.1 568449 D 316385 CDS YP_001729500.1 170080180 6060527 570737..570934 1 NC_010473.1 hypothetical protein 570934 ybdD 6060527 ybdD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729500.1 570737 D 316385 CDS YP_001729501.1 170080181 6060528 complement(570944..572032) 1 NC_010473.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 572032 ybdH 6060528 ybdH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729501.1 570944 R 316385 CDS YP_001729502.1 170080182 6060530 572141..573301 1 NC_010473.1 catalyzes the transfer of an amino moiety; putative aminotransferase 573301 ybdL 6060530 ybdL Escherichia coli str. K-12 substr. DH10B putative aminotransferase YP_001729502.1 572141 D 316385 CDS YP_001729503.1 170080183 6060543 complement(573302..573931) 1 NC_010473.1 hypothetical protein 573931 ybdM 6060543 ybdM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729503.1 573302 R 316385 CDS YP_001729504.1 170080184 6058990 complement(573904..575124) 1 NC_010473.1 hypothetical protein 575124 ybdN 6058990 ybdN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729504.1 573904 R 316385 CDS YP_001729505.1 170080185 6060548 complement(575271..576173) 1 NC_010473.1 DNA-binding transcriptional regulator 576173 ybdO 6060548 ybdO Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729505.1 575271 R 316385 CDS YP_001729506.1 170080186 6060576 complement(576382..577128) 1 NC_010473.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 577128 dsbG 6060576 dsbG Escherichia coli str. K-12 substr. DH10B disulfide isomerase/thiol-disulfide oxidase YP_001729506.1 576382 R 316385 CDS YP_001729507.1 170080187 6060578 577500..578063 1 NC_010473.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 578063 ahpC 6060578 ahpC Escherichia coli str. K-12 substr. DH10B alkyl hydroperoxide reductase subunit C YP_001729507.1 577500 D 316385 CDS YP_001729508.1 170080188 6060587 578308..579873 1 NC_010473.1 alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding 579873 ahpF 6060587 ahpF Escherichia coli str. K-12 substr. DH10B alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding YP_001729508.1 578308 D 316385 CDS YP_001729509.1 170080189 6060594 complement(579994..580422) 1 NC_010473.1 universal stress protein UP12 580422 uspG 6060594 uspG Escherichia coli str. K-12 substr. DH10B universal stress protein UP12 YP_001729509.1 579994 R 316385 CDS YP_001729510.1 170080190 6060595 580643..581881 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 581881 ybdR 6060595 ybdR Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001729510.1 580643 D 316385 CDS YP_001729511.1 170080191 6060599 complement(582112..582522) 1 NC_010473.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 582522 rnk 6060599 rnk Escherichia coli str. K-12 substr. DH10B nucleoside diphosphate kinase regulator YP_001729511.1 582112 R 316385 CDS YP_001729512.1 170080192 6060604 complement(582752..583558) 1 NC_010473.1 ribonuclease I 583558 rna 6060604 rna Escherichia coli str. K-12 substr. DH10B ribonuclease I YP_001729512.1 582752 R 316385 CDS YP_001729513.1 170080193 6060607 complement(583672..585135) 1 NC_010473.1 citrate:succinate antiporter 585135 citT 6060607 citT Escherichia coli str. K-12 substr. DH10B citrate:succinate antiporter YP_001729513.1 583672 R 316385 CDS YP_001729514.1 170080194 6060609 complement(585186..586064) 1 NC_010473.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 586064 citG 6060609 citG Escherichia coli str. K-12 substr. DH10B triphosphoribosyl-dephospho-CoA synthase YP_001729514.1 585186 R 316385 CDS YP_001729515.1 170080195 6060615 complement(586039..586590) 1 NC_010473.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 586590 citX 6060615 citX Escherichia coli str. K-12 substr. DH10B 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_001729515.1 586039 R 316385 CDS YP_001729516.1 170080196 6060618 complement(586594..588126) 1 NC_010473.1 citrate lyase, citrate-ACP transferase (alpha) subunit 588126 citF 6060618 citF Escherichia coli str. K-12 substr. DH10B citrate lyase, citrate-ACP transferase (alpha) subunit YP_001729516.1 586594 R 316385 CDS YP_001729517.1 170080197 6060635 complement(588137..589045) 1 NC_010473.1 citrate lyase, citryl-ACP lyase (beta) subunit 589045 citE 6060635 citE Escherichia coli str. K-12 substr. DH10B citrate lyase, citryl-ACP lyase (beta) subunit YP_001729517.1 588137 R 316385 CDS YP_001729518.1 170080198 6060637 complement(589042..589338) 1 NC_010473.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 589338 citD 6060637 citD Escherichia coli str. K-12 substr. DH10B citrate lyase subunit gamma YP_001729518.1 589042 R 316385 CDS YP_001729519.1 170080199 6060648 complement(589353..590411) 1 NC_010473.1 citrate lyase synthetase 590411 citC 6060648 citC Escherichia coli str. K-12 substr. DH10B citrate lyase synthetase YP_001729519.1 589353 R 316385 CDS YP_001729520.1 170080200 6060680 590790..592448 1 NC_010473.1 sensory histidine kinase in two-component regulatory system with citB 592448 citA 6060680 citA Escherichia coli str. K-12 substr. DH10B sensory histidine kinase in two-component regulatory system with citB YP_001729520.1 590790 D 316385 CDS YP_001729521.1 170080201 6060684 592417..593097 1 NC_010473.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 593097 dpiA 6060684 dpiA Escherichia coli str. K-12 substr. DH10B two-component response regulator DpiA YP_001729521.1 592417 D 316385 CDS YP_001729522.1 170080202 6060693 complement(593138..594523) 1 NC_010473.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 594523 dcuC 6060693 dcuC Escherichia coli str. K-12 substr. DH10B C4-dicarboxylate transporter DcuC YP_001729522.1 593138 R 316385 CDS YP_001729523.1 170080203 6060696 595112..595672 1 NC_010473.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 595672 pagP 6060696 pagP Escherichia coli str. K-12 substr. DH10B palmitoyl transferase YP_001729523.1 595112 D 316385 CDS YP_001729524.1 170080204 6060698 595847..596056 1 NC_010473.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 596056 cspE 6060698 cspE Escherichia coli str. K-12 substr. DH10B cold shock protein CspE YP_001729524.1 595847 D 316385 CDS YP_001729525.1 170080205 6058649 complement(596110..596493) 1 NC_010473.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 596493 crcB 6058649 crcB Escherichia coli str. K-12 substr. DH10B camphor resistance protein CrcB YP_001729525.1 596110 R 316385 CDS YP_001729526.1 170080206 6061792 597502..597705 1 NC_010473.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 597705 tatE 6061792 tatE Escherichia coli str. K-12 substr. DH10B twin arginine translocase protein E YP_001729526.1 597502 D 316385 CDS YP_001729527.1 170080207 6060715 complement(597806..598771) 1 NC_010473.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 598771 lipA 6060715 lipA Escherichia coli str. K-12 substr. DH10B lipoyl synthase YP_001729527.1 597806 R 316385 CDS YP_001729528.1 170080208 6060717 complement(598980..599933) 1 NC_010473.1 putative DNA-binding transcriptional regulator 599933 ybeF 6060717 ybeF Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001729528.1 598980 R 316385 CDS YP_001729529.1 170080209 6060719 complement(600192..600833) 1 NC_010473.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 600833 lipB 6060719 lipB Escherichia coli str. K-12 substr. DH10B lipoate-protein ligase B YP_001729529.1 600192 R 316385 CDS YP_001729530.1 170080210 6060731 complement(600934..601197) 1 NC_010473.1 hypothetical protein 601197 ybeD 6060731 ybeD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729530.1 600934 R 316385 CDS YP_001729531.1 170080211 6062416 complement(601307..602518) 1 NC_010473.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 602518 dacA 6062416 dacA Escherichia coli str. K-12 substr. DH10B D-alanyl-D-alanine carboxypeptidase YP_001729531.1 601307 R 316385 CDS YP_001729532.1 170080212 6059374 complement(602657..603745) 1 NC_010473.1 rare lipoprotein A 603745 rlpA 6059374 rlpA Escherichia coli str. K-12 substr. DH10B rare lipoprotein A YP_001729532.1 602657 R 316385 CDS YP_001729533.1 170080213 6060451 complement(603756..604868) 1 NC_010473.1 cell wall shape-determining protein 604868 mrdB 6060451 mrdB Escherichia coli str. K-12 substr. DH10B cell wall shape-determining protein YP_001729533.1 603756 R 316385 CDS YP_001729534.1 170080214 6058741 complement(604871..606772) 1 NC_010473.1 penicillin-binding protein 2 606772 mrdA 6058741 mrdA Escherichia coli str. K-12 substr. DH10B penicillin-binding protein 2 YP_001729534.1 604871 R 316385 CDS YP_001729535.1 170080215 6058885 complement(606803..607270) 1 NC_010473.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 607270 ybeA 6058885 ybeA Escherichia coli str. K-12 substr. DH10B rRNA large subunit methyltransferase YP_001729535.1 606803 R 316385 CDS YP_001729536.1 170080216 6058983 complement(607274..607591) 1 NC_010473.1 hypothetical protein 607591 ybeB 6058983 ybeB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729536.1 607274 R 316385 CDS YP_001729537.1 170080217 6059060 complement(607851..608462) 1 NC_010473.1 alpha-ribazole-5'-phosphate phosphatase 608462 cobC 6059060 cobC Escherichia coli str. K-12 substr. DH10B alpha-ribazole-5'-phosphate phosphatase YP_001729537.1 607851 R 316385 CDS YP_001729538.1 170080218 6059069 complement(608486..609127) 1 NC_010473.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 609127 nadD 6059069 nadD Escherichia coli str. K-12 substr. DH10B nicotinic acid mononucleotide adenylyltransferase YP_001729538.1 608486 R 316385 CDS YP_001729539.1 170080219 6059100 complement(609129..610160) 1 NC_010473.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 610160 holA 6059100 holA Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit delta YP_001729539.1 609129 R 316385 CDS YP_001729540.1 170080220 6059197 complement(610160..610741) 1 NC_010473.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 610741 rlpB 6059197 rlpB Escherichia coli str. K-12 substr. DH10B LPS-assembly lipoprotein RlpB YP_001729540.1 610160 R 316385 CDS YP_001729541.1 170080221 6059747 complement(610756..613338) 1 NC_010473.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 613338 leuS 6059747 leuS Escherichia coli str. K-12 substr. DH10B leucyl-tRNA synthetase YP_001729541.1 610756 R 316385 CDS YP_001729542.1 170080222 6060062 613573..614055 1 NC_010473.1 hypothetical protein 614055 ybeL 6060062 ybeL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729542.1 613573 D 316385 CDS YP_001729543.1 170080223 6060019 complement(614125..615102) 1 NC_010473.1 hypothetical protein 615102 ybeQ 6060019 ybeQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729543.1 614125 R 316385 CDS YP_001729544.1 170080224 6060489 615266..615973 1 NC_010473.1 hypothetical protein 615973 ybeR 6060489 ybeR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729544.1 615266 D 316385 CDS YP_001729545.1 170080225 6059207 615970..617397 1 NC_010473.1 chaperone 617397 djlB 6059207 djlB Escherichia coli str. K-12 substr. DH10B chaperone YP_001729545.1 615970 D 316385 CDS YP_001729546.1 170080226 6058995 complement(617407..617961) 1 NC_010473.1 outer membrane protein 617961 ybeT 6058995 ybeT Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001729546.1 617407 R 316385 CDS YP_001729547.1 170080227 6058621 618063..618770 1 NC_010473.1 tRNA ligase 618770 ybeU 6058621 ybeU Escherichia coli str. K-12 substr. DH10B tRNA ligase YP_001729547.1 618063 D 316385 CDS YP_001729548.1 170080228 6059606 618767..620218 1 NC_010473.1 Hsc56 co-chaperone of HscC 620218 djlC 6059606 djlC Escherichia coli str. K-12 substr. DH10B Hsc56 co-chaperone of HscC YP_001729548.1 618767 D 316385 CDS YP_001729549.1 170080229 6060007 complement(620278..621948) 1 NC_010473.1 Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription 621948 hscC 6060007 hscC Escherichia coli str. K-12 substr. DH10B Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription YP_001729549.1 620278 R 316385 CDS YP_001729550.1 170080230 6058609 complement(622032..622967) 1 NC_010473.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 622967 rihA 6058609 rihA Escherichia coli str. K-12 substr. DH10B ribonucleoside hydrolase 1 YP_001729550.1 622032 R 316385 CDS YP_001729551.1 170080231 6061849 complement(623085..623810) 1 NC_010473.1 glutamate/aspartate ABC transporter ATP-binding protein 623810 gltL 6061849 gltL Escherichia coli str. K-12 substr. DH10B glutamate/aspartate ABC transporter ATP-binding protein YP_001729551.1 623085 R 316385 CDS YP_001729552.1 170080232 6061850 complement(623810..624484) 1 NC_010473.1 glutamate/aspartate ABC transporter membrane protein 624484 gltK 6061850 gltK Escherichia coli str. K-12 substr. DH10B glutamate/aspartate ABC transporter membrane protein YP_001729552.1 623810 R 316385 CDS YP_001729553.1 170080233 6061843 complement(624484..625224) 1 NC_010473.1 glutamate/aspartate ABC transporter membrane protein 625224 gltJ 6061843 gltJ Escherichia coli str. K-12 substr. DH10B glutamate/aspartate ABC transporter membrane protein YP_001729553.1 624484 R 316385 CDS YP_001729554.1 170080234 6061847 complement(625394..626302) 1 NC_010473.1 glutamate and aspartate transporter subunit 626302 gltI 6061847 gltI Escherichia coli str. K-12 substr. DH10B glutamate and aspartate transporter subunit YP_001729554.1 625394 R 316385 CDS YP_001729555.1 170080235 6061853 complement(626552..627568) 1 NC_010473.1 IS5 transposase and trans-activator 627568 insH-3 6061853 insH-3 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001729555.1 626552 R 316385 CDS YP_001729556.1 170080236 6061756 629213..629428 1 NC_010473.1 DLP12 prophage; phage lysis protein 629428 essD 6061756 essD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; phage lysis protein YP_001729556.1 629213 D 316385 CDS YP_001729557.1 170080237 6061840 629428..629925 1 NC_010473.1 DLP12 prophage; lysozyme 629925 ybcS 6061840 ybcS Escherichia coli str. K-12 substr. DH10B DLP12 prophage; lysozyme YP_001729557.1 629428 D 316385 CDS YP_001729558.1 170080238 6061828 629922..630383 1 NC_010473.1 DLP12 prophage; murein endopeptidase 630383 rzpD 6061828 rzpD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; murein endopeptidase YP_001729558.1 629922 D 316385 CDS YP_001729559.1 170080239 6061831 630142..630324 1 NC_010473.1 DLP12 prophage; lipoprotein 630324 rzoD 6061831 rzoD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; lipoprotein YP_001729559.1 630142 D 316385 CDS YP_001729560.1 170080240 6061841 complement(630415..630708) 1 NC_010473.1 DLP12 prophage; lipoprotein 630708 borD 6061841 borD Escherichia coli str. K-12 substr. DH10B DLP12 prophage; lipoprotein YP_001729560.1 630415 R 316385 CDS YP_001729561.1 170080241 6061822 complement(630999..631409) 1 NC_010473.1 DLP12 prophage; hypothetical protein 631409 ybcV 6061822 ybcV Escherichia coli str. K-12 substr. DH10B DLP12 prophage; hypothetical protein YP_001729561.1 630999 R 316385 CDS YP_001729562.1 170080242 6061818 631695..631901 1 NC_010473.1 DLP12 prophage; hypothetical protein 631901 ybcW 6061818 ybcW Escherichia coli str. K-12 substr. DH10B DLP12 prophage; hypothetical protein YP_001729562.1 631695 D 316385 CDS YP_001729563.1 170080243 6061807 632649..633194 1 NC_010473.1 DLP12 prophage; DNA packaging protein 633194 nohB 6061807 nohB Escherichia coli str. K-12 substr. DH10B DLP12 prophage; DNA packaging protein YP_001729563.1 632649 D 316385 CDS YP_001729564.1 170080244 6061507 635496..636245 1 NC_010473.1 DLP12 prophage; DNA-binding transcriptional activator 636245 appY 6061507 appY Escherichia coli str. K-12 substr. DH10B DLP12 prophage; DNA-binding transcriptional activator YP_001729564.1 635496 D 316385 CDS YP_001729565.1 170080245 6061795 complement(636495..637448) 1 NC_010473.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 637448 ompT 6061795 ompT Escherichia coli str. K-12 substr. DH10B outer membrane protease YP_001729565.1 636495 R 316385 CDS YP_001729566.1 170080246 6061797 complement(637962..638723) 1 NC_010473.1 DNA-binding transcriptional activator of porin biosynthesis 638723 envY 6061797 envY Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator of porin biosynthesis YP_001729566.1 637962 R 316385 CDS YP_001729567.1 170080247 6061784 complement(638906..639796) 1 NC_010473.1 hypothetical protein 639796 ybcH 6061784 ybcH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729567.1 638906 R 316385 CDS YP_001729568.1 170080248 6061778 complement(639797..642769) 1 NC_010473.1 bacteriophage N4 receptor, outer membrane subunit 642769 nfrA 6061778 nfrA Escherichia coli str. K-12 substr. DH10B bacteriophage N4 receptor, outer membrane subunit YP_001729568.1 639797 R 316385 CDS YP_001729569.1 170080249 6061781 complement(642756..644993) 1 NC_010473.1 bacteriophage N4 adsorption protein B 644993 nfrB 6061781 nfrB Escherichia coli str. K-12 substr. DH10B bacteriophage N4 adsorption protein B YP_001729569.1 642756 R 316385 CDS YP_001729570.1 170080250 6061773 complement(645143..646585) 1 NC_010473.1 sensor kinase CusS 646585 cusS 6061773 cusS Escherichia coli str. K-12 substr. DH10B sensor kinase CusS YP_001729570.1 645143 R 316385 CDS YP_001729571.1 170080251 6061783 complement(646575..647258) 1 NC_010473.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 647258 cusR 6061783 cusR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator CusR YP_001729571.1 646575 R 316385 CDS YP_001729572.1 170080252 6061765 647415..648788 1 NC_010473.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 648788 cusC 6061765 cusC Escherichia coli str. K-12 substr. DH10B copper/silver efflux system outer membrane protein CusC YP_001729572.1 647415 D 316385 CDS YP_001729573.1 170080253 6061768 648946..649278 1 NC_010473.1 copper-binding protein 649278 cusF 6061768 cusF Escherichia coli str. K-12 substr. DH10B copper-binding protein YP_001729573.1 648946 D 316385 CDS YP_001729574.1 170080254 6061763 649294..650517 1 NC_010473.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 650517 cusB 6061763 cusB Escherichia coli str. K-12 substr. DH10B copper/silver efflux system membrane fusion protein CusB YP_001729574.1 649294 D 316385 CDS YP_001729575.1 170080255 6061771 650529..653672 1 NC_010473.1 copper/silver efflux system, membrane component 653672 cusA 6061771 cusA Escherichia coli str. K-12 substr. DH10B copper/silver efflux system, membrane component YP_001729575.1 650529 D 316385 CDS YP_001729576.1 170080256 6061754 653774..655150 1 NC_010473.1 phenylalanine transporter 655150 pheP 6061754 pheP Escherichia coli str. K-12 substr. DH10B phenylalanine transporter YP_001729576.1 653774 D 316385 CDS YP_001729577.1 170080257 6061758 complement(655231..656478) 1 NC_010473.1 mechanosensitive channel 656478 ybdG 6061758 ybdG Escherichia coli str. K-12 substr. DH10B mechanosensitive channel YP_001729577.1 655231 R 316385 CDS YP_001729578.1 170080258 6061753 complement(656586..657239) 1 NC_010473.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 657239 nfnB 6061753 nfnB Escherichia coli str. K-12 substr. DH10B dihydropteridine reductase YP_001729578.1 656586 R 316385 CDS YP_001729579.1 170080259 6061761 complement(657333..657701) 1 NC_010473.1 hypothetical protein 657701 ybdF 6061761 ybdF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729579.1 657333 R 316385 CDS YP_001729580.1 170080260 6061815 complement(657766..658014) 1 NC_010473.1 inner membrane protein 658014 ybdJ 6061815 ybdJ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729580.1 657766 R 316385 CDS YP_001729581.1 170080261 6061802 complement(658080..659198) 1 NC_010473.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 659198 ybdK 6061802 ybdK Escherichia coli str. K-12 substr. DH10B carboxylate-amine ligase YP_001729581.1 658080 R 316385 CDS YP_001729582.1 170080262 6061799 659651..659803 1 NC_010473.1 toxic polypeptide, small 659803 hokE 6061799 hokE Escherichia coli str. K-12 substr. DH10B toxic polypeptide, small YP_001729582.1 659651 D 316385 CDS YP_001729583.1 170080263 6061788 659880..660992 1 NC_010473.1 IS186/IS421 transposase 660992 insL-2 6061788 insL-2 Escherichia coli str. K-12 substr. DH10B IS186/IS421 transposase YP_001729583.1 659880 D 316385 CDS YP_001729584.1 170080264 6061744 complement(661274..661903) 1 NC_010473.1 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 661903 entD 6061744 entD Escherichia coli str. K-12 substr. DH10B phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_001729584.1 661274 R 316385 CDS YP_001729585.1 170080265 6061746 complement(662069..664309) 1 NC_010473.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 664309 fepA 6061746 fepA Escherichia coli str. K-12 substr. DH10B outer membrane receptor FepA YP_001729585.1 662069 R 316385 CDS YP_001729586.1 170080266 6061736 664630..665754 1 NC_010473.1 enterobactin/ferric enterobactin esterase 665754 fes 6061736 fes Escherichia coli str. K-12 substr. DH10B enterobactin/ferric enterobactin esterase YP_001729586.1 664630 D 316385 CDS YP_001729587.1 170080267 6061740 665757..665975 1 NC_010473.1 hypothetical protein 665975 ybdZ 6061740 ybdZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729587.1 665757 D 316385 CDS YP_001729588.1 170080268 6061748 665972..669853 1 NC_010473.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 669853 entF 6061748 entF Escherichia coli str. K-12 substr. DH10B enterobactin synthase subunit F YP_001729588.1 665972 D 316385 CDS YP_001729589.1 170080269 6061728 670069..671202 1 NC_010473.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 671202 fepE 6061728 fepE Escherichia coli str. K-12 substr. DH10B ferric enterobactin transport protein FepE YP_001729589.1 670069 D 316385 CDS YP_001729590.1 170080270 6061712 complement(671199..672014) 1 NC_010473.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 672014 fepC 6061712 fepC Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter ATP-binding protein YP_001729590.1 671199 R 316385 CDS YP_001729591.1 170080271 6061713 complement(672011..673003) 1 NC_010473.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 673003 fepG 6061713 fepG Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter permease YP_001729591.1 672011 R 316385 CDS YP_001729592.1 170080272 6061708 complement(673000..674004) 1 NC_010473.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 674004 fepD 6061708 fepD Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter membrane protein YP_001729592.1 673000 R 316385 CDS YP_001729593.1 170080273 6061696 674115..675365 1 NC_010473.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 675365 entS 6061696 entS Escherichia coli str. K-12 substr. DH10B enterobactin exporter EntS YP_001729593.1 674115 D 316385 CDS YP_001729594.1 170080274 6061699 complement(675369..676325) 1 NC_010473.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 676325 fepB 6061699 fepB Escherichia coli str. K-12 substr. DH10B iron-enterobactin transporter periplasmic binding protein YP_001729594.1 675369 R 316385 CDS YP_001729595.1 170080275 6061682 676700..677875 1 NC_010473.1 isochorismate synthase 1 677875 entC 6061682 entC Escherichia coli str. K-12 substr. DH10B isochorismate synthase 1 YP_001729595.1 676700 D 316385 CDS YP_001729596.1 170080276 6061703 677885..679495 1 NC_010473.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 679495 entE 6061703 entE Escherichia coli str. K-12 substr. DH10B enterobactin synthase subunit E YP_001729596.1 677885 D 316385 CDS YP_001729597.1 170080277 6061669 679509..680366 1 NC_010473.1 isochorismatase 680366 entB 6061669 entB Escherichia coli str. K-12 substr. DH10B isochorismatase YP_001729597.1 679509 D 316385 CDS YP_001729598.1 170080278 6061677 680366..681112 1 NC_010473.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 681112 entA 6061677 entA Escherichia coli str. K-12 substr. DH10B 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_001729598.1 680366 D 316385 CDS YP_001729599.1 170080279 6061667 681115..681528 1 NC_010473.1 hypothetical protein 681528 ybdB 6061667 ybdB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729599.1 681115 D 316385 CDS YP_001729600.1 170080280 6061679 681709..683814 1 NC_010473.1 carbon starvation protein 683814 cstA 6061679 cstA Escherichia coli str. K-12 substr. DH10B carbon starvation protein YP_001729600.1 681709 D 316385 CDS YP_001729601.1 170080281 6061715 683997..684194 1 NC_010473.1 hypothetical protein 684194 ybdD 6061715 ybdD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729601.1 683997 D 316385 CDS YP_001729602.1 170080282 6061709 complement(684204..685292) 1 NC_010473.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 685292 ybdH 6061709 ybdH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729602.1 684204 R 316385 CDS YP_001729603.1 170080283 6061661 685401..686561 1 NC_010473.1 catalyzes the transfer of an amino moiety; putative aminotransferase 686561 ybdL 6061661 ybdL Escherichia coli str. K-12 substr. DH10B putative aminotransferase YP_001729603.1 685401 D 316385 CDS YP_001729604.1 170080284 6061663 complement(686562..687191) 1 NC_010473.1 hypothetical protein 687191 ybdM 6061663 ybdM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729604.1 686562 R 316385 CDS YP_001729605.1 170080285 6061653 complement(687164..688384) 1 NC_010473.1 hypothetical protein 688384 ybdN 6061653 ybdN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729605.1 687164 R 316385 CDS YP_001729606.1 170080286 6061657 complement(688531..689433) 1 NC_010473.1 DNA-binding transcriptional regulator 689433 ybdO 6061657 ybdO Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729606.1 688531 R 316385 CDS YP_001729607.1 170080287 6061665 complement(689642..690388) 1 NC_010473.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 690388 dsbG 6061665 dsbG Escherichia coli str. K-12 substr. DH10B disulfide isomerase/thiol-disulfide oxidase YP_001729607.1 689642 R 316385 CDS YP_001729608.1 170080288 6059484 690760..691323 1 NC_010473.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 691323 ahpC 6059484 ahpC Escherichia coli str. K-12 substr. DH10B alkyl hydroperoxide reductase subunit C YP_001729608.1 690760 D 316385 CDS YP_001729609.1 170080289 6061650 691568..693133 1 NC_010473.1 alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding 693133 ahpF 6061650 ahpF Escherichia coli str. K-12 substr. DH10B alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding YP_001729609.1 691568 D 316385 CDS YP_001729610.1 170080290 6061637 complement(693254..693682) 1 NC_010473.1 universal stress protein UP12 693682 uspG 6061637 uspG Escherichia coli str. K-12 substr. DH10B universal stress protein UP12 YP_001729610.1 693254 R 316385 CDS YP_001729611.1 170080291 6061643 693903..695141 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 695141 ybdR 6061643 ybdR Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001729611.1 693903 D 316385 CDS YP_001729612.1 170080292 6061634 complement(695372..695782) 1 NC_010473.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 695782 rnk 6061634 rnk Escherichia coli str. K-12 substr. DH10B nucleoside diphosphate kinase regulator YP_001729612.1 695372 R 316385 CDS YP_001729613.1 170080293 6061626 complement(696012..696818) 1 NC_010473.1 ribonuclease I 696818 rna 6061626 rna Escherichia coli str. K-12 substr. DH10B ribonuclease I YP_001729613.1 696012 R 316385 CDS YP_001729614.1 170080294 6061628 complement(696932..698395) 1 NC_010473.1 citrate:succinate antiporter 698395 citT 6061628 citT Escherichia coli str. K-12 substr. DH10B citrate:succinate antiporter YP_001729614.1 696932 R 316385 CDS YP_001729615.1 170080295 6061624 complement(698446..699324) 1 NC_010473.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 699324 citG 6061624 citG Escherichia coli str. K-12 substr. DH10B triphosphoribosyl-dephospho-CoA synthase YP_001729615.1 698446 R 316385 CDS YP_001729616.1 170080296 6061633 complement(699299..699850) 1 NC_010473.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 699850 citX 6061633 citX Escherichia coli str. K-12 substr. DH10B 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_001729616.1 699299 R 316385 CDS YP_001729617.1 170080297 6061619 complement(699854..701386) 1 NC_010473.1 citrate lyase, citrate-ACP transferase (alpha) subunit 701386 citF 6061619 citF Escherichia coli str. K-12 substr. DH10B citrate lyase, citrate-ACP transferase (alpha) subunit YP_001729617.1 699854 R 316385 CDS YP_001729618.1 170080298 6061620 complement(701397..702305) 1 NC_010473.1 citrate lyase, citryl-ACP lyase (beta) subunit 702305 citE 6061620 citE Escherichia coli str. K-12 substr. DH10B citrate lyase, citryl-ACP lyase (beta) subunit YP_001729618.1 701397 R 316385 CDS YP_001729619.1 170080299 6061613 complement(702302..702598) 1 NC_010473.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 702598 citD 6061613 citD Escherichia coli str. K-12 substr. DH10B citrate lyase subunit gamma YP_001729619.1 702302 R 316385 CDS YP_001729620.1 170080300 6061622 complement(702613..703671) 1 NC_010473.1 citrate lyase synthetase 703671 citC 6061622 citC Escherichia coli str. K-12 substr. DH10B citrate lyase synthetase YP_001729620.1 702613 R 316385 CDS YP_001729621.1 170080301 6061649 704050..705708 1 NC_010473.1 sensory histidine kinase in two-component regulatory system with citB 705708 citA 6061649 citA Escherichia coli str. K-12 substr. DH10B sensory histidine kinase in two-component regulatory system with citB YP_001729621.1 704050 D 316385 CDS YP_001729622.1 170080302 6061635 705677..706357 1 NC_010473.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 706357 dpiA 6061635 dpiA Escherichia coli str. K-12 substr. DH10B two-component response regulator DpiA YP_001729622.1 705677 D 316385 CDS YP_001729623.1 170080303 6061606 complement(706398..707783) 1 NC_010473.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 707783 dcuC 6061606 dcuC Escherichia coli str. K-12 substr. DH10B C4-dicarboxylate transporter DcuC YP_001729623.1 706398 R 316385 CDS YP_001729624.1 170080304 6061607 708372..708932 1 NC_010473.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 708932 pagP 6061607 pagP Escherichia coli str. K-12 substr. DH10B palmitoyl transferase YP_001729624.1 708372 D 316385 CDS YP_001729625.1 170080305 6061604 709107..709316 1 NC_010473.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 709316 cspE 6061604 cspE Escherichia coli str. K-12 substr. DH10B cold shock protein CspE YP_001729625.1 709107 D 316385 CDS YP_001729626.1 170080306 6061605 complement(709370..709753) 1 NC_010473.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 709753 crcB 6061605 crcB Escherichia coli str. K-12 substr. DH10B camphor resistance protein CrcB YP_001729626.1 709370 R 316385 CDS YP_001729627.1 170080307 6061464 710762..710965 1 NC_010473.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 710965 tatE 6061464 tatE Escherichia coli str. K-12 substr. DH10B twin arginine translocase protein E YP_001729627.1 710762 D 316385 CDS YP_001729628.1 170080308 6061601 complement(711066..712031) 1 NC_010473.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 712031 lipA 6061601 lipA Escherichia coli str. K-12 substr. DH10B lipoyl synthase YP_001729628.1 711066 R 316385 CDS YP_001729629.1 170080309 6061593 complement(712240..713193) 1 NC_010473.1 putative DNA-binding transcriptional regulator 713193 ybeF 6061593 ybeF Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001729629.1 712240 R 316385 CDS YP_001729630.1 170080310 6061594 complement(713452..714093) 1 NC_010473.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 714093 lipB 6061594 lipB Escherichia coli str. K-12 substr. DH10B lipoate-protein ligase B YP_001729630.1 713452 R 316385 CDS YP_001729631.1 170080311 6061584 complement(714194..714457) 1 NC_010473.1 hypothetical protein 714457 ybeD 6061584 ybeD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729631.1 714194 R 316385 CDS YP_001729632.1 170080312 6061576 complement(714567..715778) 1 NC_010473.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 715778 dacA 6061576 dacA Escherichia coli str. K-12 substr. DH10B D-alanyl-D-alanine carboxypeptidase YP_001729632.1 714567 R 316385 CDS YP_001729633.1 170080313 6061569 complement(715917..717005) 1 NC_010473.1 rare lipoprotein A 717005 rlpA 6061569 rlpA Escherichia coli str. K-12 substr. DH10B rare lipoprotein A YP_001729633.1 715917 R 316385 CDS YP_001729634.1 170080314 6061573 complement(717016..718128) 1 NC_010473.1 cell wall shape-determining protein 718128 mrdB 6061573 mrdB Escherichia coli str. K-12 substr. DH10B cell wall shape-determining protein YP_001729634.1 717016 R 316385 CDS YP_001729635.1 170080315 6061562 complement(718131..720032) 1 NC_010473.1 penicillin-binding protein 2 720032 mrdA 6061562 mrdA Escherichia coli str. K-12 substr. DH10B penicillin-binding protein 2 YP_001729635.1 718131 R 316385 CDS YP_001729636.1 170080316 6061575 complement(720063..720530) 1 NC_010473.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 720530 ybeA 6061575 ybeA Escherichia coli str. K-12 substr. DH10B rRNA large subunit methyltransferase YP_001729636.1 720063 R 316385 CDS YP_001729637.1 170080317 6061552 complement(720534..720851) 1 NC_010473.1 hypothetical protein 720851 ybeB 6061552 ybeB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729637.1 720534 R 316385 CDS YP_001729638.1 170080318 6061556 complement(721111..721722) 1 NC_010473.1 alpha-ribazole-5'-phosphate phosphatase 721722 cobC 6061556 cobC Escherichia coli str. K-12 substr. DH10B alpha-ribazole-5'-phosphate phosphatase YP_001729638.1 721111 R 316385 CDS YP_001729639.1 170080319 6061549 complement(721746..722387) 1 NC_010473.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 722387 nadD 6061549 nadD Escherichia coli str. K-12 substr. DH10B nicotinic acid mononucleotide adenylyltransferase YP_001729639.1 721746 R 316385 CDS YP_001729640.1 170080320 6061561 complement(722389..723420) 1 NC_010473.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 723420 holA 6061561 holA Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit delta YP_001729640.1 722389 R 316385 CDS YP_001729641.1 170080321 6061598 complement(723420..724001) 1 NC_010473.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 724001 rlpB 6061598 rlpB Escherichia coli str. K-12 substr. DH10B LPS-assembly lipoprotein RlpB YP_001729641.1 723420 R 316385 CDS YP_001729642.1 170080322 6061586 complement(724016..726598) 1 NC_010473.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 726598 leuS 6061586 leuS Escherichia coli str. K-12 substr. DH10B leucyl-tRNA synthetase YP_001729642.1 724016 R 316385 CDS YP_001729643.1 170080323 6059098 726833..727315 1 NC_010473.1 hypothetical protein 727315 ybeL 6059098 ybeL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729643.1 726833 D 316385 CDS YP_001729644.1 170080324 6061542 complement(727385..728362) 1 NC_010473.1 hypothetical protein 728362 ybeQ 6061542 ybeQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729644.1 727385 R 316385 CDS YP_001729645.1 170080325 6061544 728526..729233 1 NC_010473.1 hypothetical protein 729233 ybeR 6061544 ybeR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729645.1 728526 D 316385 CDS YP_001729646.1 170080326 6061529 729230..730657 1 NC_010473.1 chaperone 730657 djlB 6061529 djlB Escherichia coli str. K-12 substr. DH10B chaperone YP_001729646.1 729230 D 316385 CDS YP_001729647.1 170080327 6061535 complement(730667..731221) 1 NC_010473.1 outer membrane protein 731221 ybeT 6061535 ybeT Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001729647.1 730667 R 316385 CDS YP_001729648.1 170080328 6061548 731323..732030 1 NC_010473.1 tRNA ligase 732030 ybeU 6061548 ybeU Escherichia coli str. K-12 substr. DH10B tRNA ligase YP_001729648.1 731323 D 316385 CDS YP_001729649.1 170080329 6061525 732027..733478 1 NC_010473.1 Hsc56 co-chaperone of HscC 733478 djlC 6061525 djlC Escherichia coli str. K-12 substr. DH10B Hsc56 co-chaperone of HscC YP_001729649.1 732027 D 316385 CDS YP_001729650.1 170080330 6061520 complement(733538..735208) 1 NC_010473.1 Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription 735208 hscC 6061520 hscC Escherichia coli str. K-12 substr. DH10B Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription YP_001729650.1 733538 R 316385 CDS YP_001729651.1 170080331 6061522 complement(735292..736227) 1 NC_010473.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 736227 rihA 6061522 rihA Escherichia coli str. K-12 substr. DH10B ribonucleoside hydrolase 1 YP_001729651.1 735292 R 316385 CDS YP_001729652.1 170080332 6061517 complement(736345..737070) 1 NC_010473.1 glutamate/aspartate ABC transporter ATP-binding protein 737070 gltL 6061517 gltL Escherichia coli str. K-12 substr. DH10B glutamate/aspartate ABC transporter ATP-binding protein YP_001729652.1 736345 R 316385 CDS YP_001729653.1 170080333 6061509 complement(737070..737744) 1 NC_010473.1 glutamate/aspartate ABC transporter membrane protein 737744 gltK 6061509 gltK Escherichia coli str. K-12 substr. DH10B glutamate/aspartate ABC transporter membrane protein YP_001729653.1 737070 R 316385 CDS YP_001729654.1 170080334 6061512 complement(737744..738484) 1 NC_010473.1 glutamate/aspartate ABC transporter membrane protein 738484 gltJ 6061512 gltJ Escherichia coli str. K-12 substr. DH10B glutamate/aspartate ABC transporter membrane protein YP_001729654.1 737744 R 316385 CDS YP_001729655.1 170080335 6061500 complement(738654..739562) 1 NC_010473.1 glutamate and aspartate transporter subunit 739562 gltI 6061500 gltI Escherichia coli str. K-12 substr. DH10B glutamate and aspartate transporter subunit YP_001729655.1 738654 R 316385 CDS YP_001729656.1 170080336 6061514 complement(739812..740828) 1 NC_010473.1 IS5 transposase and trans-activator 740828 6061514 ECDH10B_0725 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001729656.1 739812 R 316385 CDS YP_001729657.1 170080337 6061493 complement(741158..742696) 1 NC_010473.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 742696 lnt 6061493 lnt Escherichia coli str. K-12 substr. DH10B apolipoprotein N-acyltransferase YP_001729657.1 741158 R 316385 CDS YP_001729658.1 170080338 6061497 complement(742721..743599) 1 NC_010473.1 ion transport 743599 corC 6061497 corC Escherichia coli str. K-12 substr. DH10B ion transport YP_001729658.1 742721 R 316385 CDS YP_001729659.1 170080339 6061491 complement(743689..744156) 1 NC_010473.1 putative metalloprotease 744156 ybeY 6061491 ybeY Escherichia coli str. K-12 substr. DH10B putative metalloprotease YP_001729659.1 743689 R 316385 CDS YP_001729660.1 170080340 6061499 complement(744153..745193) 1 NC_010473.1 nucleoside triphosphate hydrolase domain-containing protein 745193 ybeZ 6061499 ybeZ Escherichia coli str. K-12 substr. DH10B nucleoside triphosphate hydrolase domain-containing protein YP_001729660.1 744153 R 316385 CDS YP_001729661.1 170080341 6061524 complement(745346..746770) 1 NC_010473.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 746770 miaB 6061524 miaB Escherichia coli str. K-12 substr. DH10B (dimethylallyl)adenosine tRNA methylthiotransferase YP_001729661.1 745346 R 316385 CDS YP_001729662.1 170080342 6061519 746916..748091 1 NC_010473.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 748091 ubiF 6061519 ubiF Escherichia coli str. K-12 substr. DH10B 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_001729662.1 746916 D 316385 CDS YP_001729663.1 170080343 6061769 complement(749328..750992) 1 NC_010473.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 750992 asnB 6061769 asnB Escherichia coli str. K-12 substr. DH10B asparagine synthetase B YP_001729663.1 749328 R 316385 CDS YP_001729664.1 170080344 6061479 complement(751389..752141) 1 NC_010473.1 UMP phosphatase 752141 nagD 6061479 nagD Escherichia coli str. K-12 substr. DH10B UMP phosphatase YP_001729664.1 751389 R 316385 CDS YP_001729665.1 170080345 6061472 complement(752189..753409) 1 NC_010473.1 DNA-binding transcriptional dual regulator 753409 nagC 6061472 nagC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional dual regulator YP_001729665.1 752189 R 316385 CDS YP_001729666.1 170080346 6061473 complement(753418..754566) 1 NC_010473.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 754566 nagA 6061473 nagA Escherichia coli str. K-12 substr. DH10B N-acetylglucosamine-6-phosphate deacetylase YP_001729666.1 753418 R 316385 CDS YP_001729667.1 170080347 6061489 complement(754626..755426) 1 NC_010473.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 755426 nagB 6061489 nagB Escherichia coli str. K-12 substr. DH10B glucosamine-6-phosphate deaminase YP_001729667.1 754626 R 316385 CDS YP_001729668.1 170080348 6061470 755759..757705 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 757705 nagE 6061470 nagE Escherichia coli str. K-12 substr. DH10B PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_001729668.1 755759 D 316385 CDS YP_001729669.1 170080349 6061458 757908..759572 1 NC_010473.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 759572 glnS 6061458 glnS Escherichia coli str. K-12 substr. DH10B glutaminyl-tRNA synthetase YP_001729669.1 757908 D 316385 CDS YP_001729670.1 170080350 6061466 760149..761555 1 NC_010473.1 outer membrane porin 761555 ybfM 6061466 ybfM Escherichia coli str. K-12 substr. DH10B outer membrane porin YP_001729670.1 760149 D 316385 CDS YP_001729671.1 170080351 6061453 761605..761931 1 NC_010473.1 lipoprotein 761931 ybfN 6061453 ybfN Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001729671.1 761605 D 316385 CDS YP_001729672.1 170080352 6061442 complement(762015..762461) 1 NC_010473.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 762461 fur 6061442 fur Escherichia coli str. K-12 substr. DH10B ferric uptake regulator YP_001729672.1 762015 R 316385 CDS YP_001729673.1 170080353 6061448 complement(762750..763280) 1 NC_010473.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 763280 fldA 6061448 fldA Escherichia coli str. K-12 substr. DH10B flavodoxin FldA YP_001729673.1 762750 R 316385 CDS YP_001729674.1 170080354 6061438 complement(763420..763713) 1 NC_010473.1 LexA regulated protein 763713 ybfE 6061438 ybfE Escherichia coli str. K-12 substr. DH10B LexA regulated protein YP_001729674.1 763420 R 316385 CDS YP_001729675.1 170080355 6061451 complement(763853..764617) 1 NC_010473.1 hypothetical protein 764617 ybfF 6061451 ybfF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729675.1 763853 R 316385 CDS YP_001729676.1 170080356 6061434 764802..765347 1 NC_010473.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 765347 seqA 6061434 seqA Escherichia coli str. K-12 substr. DH10B replication initiation regulator SeqA YP_001729676.1 764802 D 316385 CDS YP_001729677.1 170080357 6061435 765373..767013 1 NC_010473.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 767013 pgm 6061435 pgm Escherichia coli str. K-12 substr. DH10B phosphoglucomutase YP_001729677.1 765373 D 316385 CDS YP_001729678.1 170080358 6061429 767227..767721 1 NC_010473.1 hypothetical protein 767721 ybfP 6061429 ybfP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729678.1 767227 D 316385 CDS YP_001729679.1 170080359 6061283 complement(768761..770080) 1 NC_010473.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 770080 potE 6061283 potE Escherichia coli str. K-12 substr. DH10B putrescine transporter YP_001729679.1 768761 R 316385 CDS YP_001729680.1 170080360 6061469 complement(770077..772275) 1 NC_010473.1 ornithine decarboxylase 772275 speF 6061469 speF Escherichia coli str. K-12 substr. DH10B ornithine decarboxylase YP_001729680.1 770077 R 316385 CDS YP_001729681.1 170080361 6061456 complement(772871..773548) 1 NC_010473.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 773548 kdpE 6061456 kdpE Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator KdpE YP_001729681.1 772871 R 316385 CDS YP_001729682.1 170080362 6061424 complement(773545..776229) 1 NC_010473.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 776229 kdpD 6061424 kdpD Escherichia coli str. K-12 substr. DH10B sensor protein KdpD YP_001729682.1 773545 R 316385 CDS YP_001729683.1 170080363 6061426 complement(776222..776794) 1 NC_010473.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 776794 kdpC 6061426 kdpC Escherichia coli str. K-12 substr. DH10B potassium-transporting ATPase subunit C YP_001729683.1 776222 R 316385 CDS YP_001729684.1 170080364 6061422 complement(776803..778851) 1 NC_010473.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 778851 kdpB 6061422 kdpB Escherichia coli str. K-12 substr. DH10B potassium-transporting ATPase subunit B YP_001729684.1 776803 R 316385 CDS YP_001729685.1 170080365 6061423 complement(778874..780547) 1 NC_010473.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 780547 kdpA 6061423 kdpA Escherichia coli str. K-12 substr. DH10B potassium-transporting ATPase subunit A YP_001729685.1 778874 R 316385 CDS YP_001729686.1 170080366 6061427 complement(780547..780636) 1 NC_010473.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit F 780636 kdpF 6061427 kdpF Escherichia coli str. K-12 substr. DH10B potassium-transporting ATPase subunit F YP_001729686.1 780547 R 316385 CDS YP_001729687.1 170080367 6061420 780949..781155 1 NC_010473.1 hypothetical protein 781155 ybfA 6061420 ybfA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729687.1 780949 D 316385 CDS YP_001729688.1 170080368 6061414 781398..785591 1 NC_010473.1 rhsC element core protein RhsC 785591 rhsC 6061414 rhsC Escherichia coli str. K-12 substr. DH10B rhsC element core protein RhsC YP_001729688.1 781398 D 316385 CDS YP_001729689.1 170080369 6061417 785591..785917 1 NC_010473.1 inner membrane protein 785917 ybfB 6061417 ybfB Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729689.1 785591 D 316385 CDS YP_001729690.1 170080370 6061407 786035..787468 1 NC_010473.1 protein, rhs-like protein 787468 ybfO 6061407 ybfO Escherichia coli str. K-12 substr. DH10B protein, rhs-like protein YP_001729690.1 786035 D 316385 CDS YP_001729691.1 170080371 6061391 787465..788034 1 NC_010473.1 hypothetical protein 788034 ybfC 6061391 ybfC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729691.1 787465 D 316385 CDS YP_001729692.1 170080372 6061396 788260..788514 1 NC_010473.1 transposase 788514 ybfQ 6061396 ybfQ Escherichia coli str. K-12 substr. DH10B transposase YP_001729692.1 788260 D 316385 CDS YP_001729693.1 170080373 6058485 789907..790668 1 NC_010473.1 hypothetical protein 790668 ybfD 6058485 ybfD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729693.1 789907 D 316385 CDS YP_001729694.1 170080374 6061404 790816..791325 1 NC_010473.1 hypothetical protein 791325 ybgA 6061404 ybgA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729694.1 790816 D 316385 CDS YP_001729695.1 170080375 6061381 791322..792740 1 NC_010473.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 792740 phr 6061381 phr Escherichia coli str. K-12 substr. DH10B deoxyribodipyrimidine photolyase YP_001729695.1 791322 D 316385 CDS YP_001729696.1 170080376 6061382 complement(792890..794371) 1 NC_010473.1 transporter 794371 ybgH 6061382 ybgH Escherichia coli str. K-12 substr. DH10B transporter YP_001729696.1 792890 R 316385 CDS YP_001729697.1 170080377 6061379 794642..795385 1 NC_010473.1 putative hydrolase-oxidase 795385 ybgI 6061379 ybgI Escherichia coli str. K-12 substr. DH10B putative hydrolase-oxidase YP_001729697.1 794642 D 316385 CDS YP_001729698.1 170080378 6061388 795408..796064 1 NC_010473.1 allophanate hydrolase subunit 1 796064 ybgJ 6061388 ybgJ Escherichia coli str. K-12 substr. DH10B allophanate hydrolase subunit 1 YP_001729698.1 795408 D 316385 CDS YP_001729699.1 170080379 6061418 796058..796990 1 NC_010473.1 allophanate hydrolase subunit 2 796990 ybgK 6061418 ybgK Escherichia coli str. K-12 substr. DH10B allophanate hydrolase subunit 2 YP_001729699.1 796058 D 316385 CDS YP_001729700.1 170080380 6061411 796980..797714 1 NC_010473.1 LamB/YcsF family protein 797714 ybgL 6061411 ybgL Escherichia coli str. K-12 substr. DH10B LamB/YcsF family protein YP_001729700.1 796980 D 316385 CDS YP_001729701.1 170080381 6061373 797750..798541 1 NC_010473.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 798541 nei 6061373 nei Escherichia coli str. K-12 substr. DH10B endonuclease VIII YP_001729701.1 797750 D 316385 CDS YP_001729702.1 170080382 6061376 complement(798538..799584) 1 NC_010473.1 regulator 799584 abrB 6061376 abrB Escherichia coli str. K-12 substr. DH10B regulator YP_001729702.1 798538 R 316385 CDS YP_001729703.1 170080383 6061365 complement(799736..800797) 1 NC_010473.1 fimbrial-like adhesin protein 800797 ybgO 6061365 ybgO Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729703.1 799736 R 316385 CDS YP_001729704.1 170080384 6061368 complement(800794..801522) 1 NC_010473.1 assembly protein 801522 ybgP 6061368 ybgP Escherichia coli str. K-12 substr. DH10B assembly protein YP_001729704.1 800794 R 316385 CDS YP_001729705.1 170080385 6061378 complement(801537..803984) 1 NC_010473.1 outer membrane protein 803984 ybgQ 6061378 ybgQ Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001729705.1 801537 R 316385 CDS YP_001729706.1 170080386 6061362 complement(804044..804610) 1 NC_010473.1 fimbrial-like adhesin protein 804610 ybgD 6061362 ybgD Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729706.1 804044 R 316385 CDS YP_001729707.1 170080387 6061339 complement(805000..806283) 1 NC_010473.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 806283 gltA 6061339 gltA Escherichia coli str. K-12 substr. DH10B type II citrate synthase YP_001729707.1 805000 R 316385 CDS YP_001729708.1 170080388 6061355 806992..807381 1 NC_010473.1 succinate dehydrogenase cytochrome b556 large membrane subunit 807381 sdhC 6061355 sdhC Escherichia coli str. K-12 substr. DH10B succinate dehydrogenase cytochrome b556 large membrane subunit YP_001729708.1 806992 D 316385 CDS YP_001729709.1 170080389 6061335 807375..807722 1 NC_010473.1 succinate dehydrogenase cytochrome b556 small membrane subunit 807722 sdhD 6061335 sdhD Escherichia coli str. K-12 substr. DH10B succinate dehydrogenase cytochrome b556 small membrane subunit YP_001729709.1 807375 D 316385 CDS YP_001729710.1 170080390 6061321 807722..809488 1 NC_010473.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 809488 sdhA 6061321 sdhA Escherichia coli str. K-12 substr. DH10B succinate dehydrogenase flavoprotein subunit YP_001729710.1 807722 D 316385 CDS YP_001729711.1 170080391 6061325 809504..810220 1 NC_010473.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 810220 sdhB 6061325 sdhB Escherichia coli str. K-12 substr. DH10B succinate dehydrogenase iron-sulfur subunit YP_001729711.1 809504 D 316385 CDS YP_001729712.1 170080392 6061319 810521..813322 1 NC_010473.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 813322 sucA 6061319 sucA Escherichia coli str. K-12 substr. DH10B 2-oxoglutarate dehydrogenase E1 component YP_001729712.1 810521 D 316385 CDS YP_001729713.1 170080393 6061328 813337..814554 1 NC_010473.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 814554 sucB 6061328 sucB Escherichia coli str. K-12 substr. DH10B dihydrolipoamide succinyltransferase YP_001729713.1 813337 D 316385 CDS YP_001729714.1 170080394 6061306 814829..815995 1 NC_010473.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 815995 sucC 6061306 sucC Escherichia coli str. K-12 substr. DH10B succinyl-CoA synthetase subunit beta YP_001729714.1 814829 D 316385 CDS YP_001729715.1 170080395 6061313 815995..816864 1 NC_010473.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 816864 sucD 6061313 sucD Escherichia coli str. K-12 substr. DH10B succinyl-CoA synthetase subunit alpha YP_001729715.1 815995 D 316385 CDS YP_001729716.1 170080396 6061302 complement(816968..817690) 1 NC_010473.1 regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 817690 mngR 6061302 mngR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor MngR YP_001729716.1 816968 R 316385 CDS YP_001729717.1 170080397 6061317 817799..819775 1 NC_010473.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 819775 mngA 6061317 mngA Escherichia coli str. K-12 substr. DH10B PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC YP_001729717.1 817799 D 316385 CDS YP_001729718.1 170080398 6061356 819793..822426 1 NC_010473.1 alpha-mannosidase 822426 mngB 6061356 mngB Escherichia coli str. K-12 substr. DH10B alpha-mannosidase YP_001729718.1 819793 D 316385 CDS YP_001729719.1 170080399 6061337 823273..824841 1 NC_010473.1 cytochrome d terminal oxidase, subunit I 824841 cydA 6061337 cydA Escherichia coli str. K-12 substr. DH10B cytochrome d terminal oxidase, subunit I YP_001729719.1 823273 D 316385 CDS YP_001729720.1 170080400 6061288 824857..825996 1 NC_010473.1 cytochrome d terminal oxidase, subunit II 825996 cydB 6061288 cydB Escherichia coli str. K-12 substr. DH10B cytochrome d terminal oxidase, subunit II YP_001729720.1 824857 D 316385 CDS YP_001729721.1 170080401 6061291 826011..826124 1 NC_010473.1 hypothetical protein 826124 ybgT 6061291 ybgT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729721.1 826011 D 316385 CDS YP_001729722.1 170080402 6061280 826124..826417 1 NC_010473.1 hypothetical protein 826417 ybgE 6061280 ybgE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729722.1 826124 D 316385 CDS YP_001729723.1 170080403 6061286 826567..826971 1 NC_010473.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 826971 ybgC 6061286 ybgC Escherichia coli str. K-12 substr. DH10B acyl-CoA thioester hydrolase YbgC YP_001729723.1 826567 D 316385 CDS YP_001729724.1 170080404 6061293 826968..827660 1 NC_010473.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 827660 tolQ 6061293 tolQ Escherichia coli str. K-12 substr. DH10B colicin uptake protein TolQ YP_001729724.1 826968 D 316385 CDS YP_001729725.1 170080405 6061274 827664..828092 1 NC_010473.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 828092 tolR 6061274 tolR Escherichia coli str. K-12 substr. DH10B colicin uptake protein TolR YP_001729725.1 827664 D 316385 CDS YP_001729726.1 170080406 6061260 828157..829422 1 NC_010473.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 829422 tolA 6061260 tolA Escherichia coli str. K-12 substr. DH10B cell envelope integrity inner membrane protein TolA YP_001729726.1 828157 D 316385 CDS YP_001729727.1 170080407 6061267 829555..830847 1 NC_010473.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 830847 tolB 6061267 tolB Escherichia coli str. K-12 substr. DH10B translocation protein TolB YP_001729727.1 829555 D 316385 CDS YP_001729728.1 170080408 6061254 830882..831403 1 NC_010473.1 peptidoglycan-associated outer membrane lipoprotein 831403 pal 6061254 pal Escherichia coli str. K-12 substr. DH10B peptidoglycan-associated outer membrane lipoprotein YP_001729728.1 830882 D 316385 CDS YP_001729729.1 170080409 6061237 831413..832204 1 NC_010473.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 832204 ybgF 6061237 ybgF Escherichia coli str. K-12 substr. DH10B tol-pal system protein YbgF YP_001729729.1 831413 D 316385 CDS YP_001729730.1 170080410 6062128 833900..834943 1 NC_010473.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 834943 nadA 6062128 nadA Escherichia coli str. K-12 substr. DH10B quinolinate synthetase YP_001729730.1 833900 D 316385 CDS YP_001729731.1 170080411 6061235 834981..835700 1 NC_010473.1 nicotinamide mononucleotide transporter 835700 pnuC 6061235 pnuC Escherichia coli str. K-12 substr. DH10B nicotinamide mononucleotide transporter YP_001729731.1 834981 D 316385 CDS YP_001729732.1 170080412 6061248 complement(835697..836638) 1 NC_010473.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 836638 zitB 6061248 zitB Escherichia coli str. K-12 substr. DH10B zinc transporter ZitB YP_001729732.1 835697 R 316385 CDS YP_001729733.1 170080413 6061213 complement(836752..837132) 1 NC_010473.1 hypothetical protein 837132 ybgS 6061213 ybgS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729733.1 836752 R 316385 CDS YP_001729734.1 170080414 6061215 837448..838500 1 NC_010473.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 838500 aroG 6061215 aroG Escherichia coli str. K-12 substr. DH10B phospho-2-dehydro-3-deoxyheptonate aldolase YP_001729734.1 837448 D 316385 CDS YP_001729735.1 170080415 6061197 complement(838658..839410) 1 NC_010473.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 839410 gpmA 6061197 gpmA Escherichia coli str. K-12 substr. DH10B phosphoglyceromutase YP_001729735.1 838658 R 316385 CDS YP_001729736.1 170080416 6061225 complement(839612..840652) 1 NC_010473.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 840652 galM 6061225 galM Escherichia coli str. K-12 substr. DH10B aldose 1-epimerase YP_001729736.1 839612 R 316385 CDS YP_001729737.1 170080417 6061289 complement(843134..844180) 1 NC_010473.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 844180 galT 6061289 galT Escherichia coli str. K-12 substr. DH10B galactose-1-phosphate uridylyltransferase YP_001729737.1 843134 R 316385 CDS YP_001729738.1 170080418 6061257 complement(844190..845206) 1 NC_010473.1 UDP-galactose-4-epimerase 845206 galE 6061257 galE Escherichia coli str. K-12 substr. DH10B UDP-galactose-4-epimerase YP_001729738.1 844190 R 316385 CDS YP_001729739.1 170080419 6061180 complement(845467..846939) 1 NC_010473.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF 846939 modF 6061180 modF Escherichia coli str. K-12 substr. DH10B putative molybdenum transport ATP-binding protein ModF YP_001729739.1 845467 R 316385 CDS YP_001729740.1 170080420 6061183 complement(847007..847795) 1 NC_010473.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 847795 modE 6061183 modE Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator ModE YP_001729740.1 847007 R 316385 CDS YP_001729741.1 170080421 6061176 847924..848073 1 NC_010473.1 hypothetical protein 848073 ybhT 6061176 ybhT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729741.1 847924 D 316385 CDS YP_001729742.1 170080422 6061177 848240..849013 1 NC_010473.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 849013 modA 6061177 modA Escherichia coli str. K-12 substr. DH10B molybdate transporter periplasmic protein YP_001729742.1 848240 D 316385 CDS YP_001729743.1 170080423 6061193 849013..849702 1 NC_010473.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 849702 modB 6061193 modB Escherichia coli str. K-12 substr. DH10B molybdate ABC transporter permease YP_001729743.1 849013 D 316385 CDS YP_001729744.1 170080424 6061174 849705..850763 1 NC_010473.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 850763 modC 6061174 modC Escherichia coli str. K-12 substr. DH10B molybdate transporter ATP-binding protein YP_001729744.1 849705 D 316385 CDS YP_001729745.1 170080425 6061165 complement(850764..851582) 1 NC_010473.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 851582 ybhA 6061165 ybhA Escherichia coli str. K-12 substr. DH10B phosphotransferase YP_001729745.1 850764 R 316385 CDS YP_001729746.1 170080426 6061170 851737..852732 1 NC_010473.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 852732 pgl 6061170 pgl Escherichia coli str. K-12 substr. DH10B 6-phosphogluconolactonase YP_001729746.1 851737 D 316385 CDS YP_001729747.1 170080427 6061159 complement(852773..853726) 1 NC_010473.1 DNA-binding transcriptional regulator 853726 ybhD 6061159 ybhD Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729747.1 852773 R 316385 CDS YP_001729748.1 170080428 6061143 853910..854962 1 NC_010473.1 hypothetical protein 854962 ybhH 6061143 ybhH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729748.1 853910 D 316385 CDS YP_001729749.1 170080429 6061145 855038..856471 1 NC_010473.1 transporter 856471 ybhI 6061145 ybhI Escherichia coli str. K-12 substr. DH10B transporter YP_001729749.1 855038 D 316385 CDS YP_001729750.1 170080430 6061137 856654..858915 1 NC_010473.1 hypothetical protein 858915 ybhJ 6061137 ybhJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729750.1 856654 D 316385 CDS YP_001729751.1 170080431 6061157 complement(859149..860432) 1 NC_010473.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase 860432 ybhC 6061157 ybhC Escherichia coli str. K-12 substr. DH10B putative pectinesterase YP_001729751.1 859149 R 316385 CDS YP_001729752.1 170080432 6061127 complement(860584..861060) 1 NC_010473.1 YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein 861060 ybhB 6061127 ybhB Escherichia coli str. K-12 substr. DH10B putative kinase inhibitor protein YP_001729752.1 860584 R 316385 CDS YP_001729753.1 170080433 6061129 complement(861119..862408) 1 NC_010473.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 862408 bioA 6061129 bioA Escherichia coli str. K-12 substr. DH10B adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001729753.1 861119 R 316385 CDS YP_001729754.1 170080434 6061126 862495..863535 1 NC_010473.1 biotin synthase 863535 bioB 6061126 bioB Escherichia coli str. K-12 substr. DH10B biotin synthase YP_001729754.1 862495 D 316385 CDS YP_001729755.1 170080435 6061136 863532..864686 1 NC_010473.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 864686 bioF 6061136 bioF Escherichia coli str. K-12 substr. DH10B 8-amino-7-oxononanoate synthase YP_001729755.1 863532 D 316385 CDS YP_001729756.1 170080436 6061173 864673..865428 1 NC_010473.1 putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 865428 bioC 6061173 bioC Escherichia coli str. K-12 substr. DH10B biotin biosynthesis protein BioC YP_001729756.1 864673 D 316385 CDS YP_001729757.1 170080437 6061163 865421..866098 1 NC_010473.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 866098 bioD 6061163 bioD Escherichia coli str. K-12 substr. DH10B dithiobiotin synthetase YP_001729757.1 865421 D 316385 CDS YP_001729758.1 170080438 6061119 866677..868698 1 NC_010473.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 868698 uvrB 6061119 uvrB Escherichia coli str. K-12 substr. DH10B excinuclease ABC subunit B YP_001729758.1 866677 D 316385 CDS YP_001729759.1 170080439 6061122 complement(868890..869798) 1 NC_010473.1 transferase 869798 ybhK 6061122 ybhK Escherichia coli str. K-12 substr. DH10B transferase YP_001729759.1 868890 R 316385 CDS YP_001729760.1 170080440 6061096 870195..871184 1 NC_010473.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 871184 moaA 6061096 moaA Escherichia coli str. K-12 substr. DH10B molybdenum cofactor biosynthesis protein A YP_001729760.1 870195 D 316385 CDS YP_001729761.1 170080441 6061097 871206..871718 1 NC_010473.1 molybdopterin biosynthesis protein B 871718 moaB 6061097 moaB Escherichia coli str. K-12 substr. DH10B molybdopterin biosynthesis protein B YP_001729761.1 871206 D 316385 CDS YP_001729762.1 170080442 6061125 871721..872206 1 NC_010473.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 872206 moaC 6061125 moaC Escherichia coli str. K-12 substr. DH10B molybdenum cofactor biosynthesis protein MoaC YP_001729762.1 871721 D 316385 CDS YP_001729763.1 170080443 6061094 872199..872444 1 NC_010473.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 872444 moaD 6061094 moaD Escherichia coli str. K-12 substr. DH10B molybdopterin synthase small subunit YP_001729763.1 872199 D 316385 CDS YP_001729764.1 170080444 6061087 872446..872898 1 NC_010473.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 872898 moaE 6061087 moaE Escherichia coli str. K-12 substr. DH10B molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_001729764.1 872446 D 316385 CDS YP_001729765.1 170080445 6061089 873035..873739 1 NC_010473.1 inner membrane protein 873739 ybhL 6061089 ybhL Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729765.1 873035 D 316385 CDS YP_001729766.1 170080446 6061079 873944..874657 1 NC_010473.1 inner membrane protein 874657 ybhM 6061079 ybhM Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729766.1 873944 D 316385 CDS YP_001729767.1 170080447 6061068 complement(874693..875649) 1 NC_010473.1 inner membrane protein 875649 ybhN 6061068 ybhN Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729767.1 874693 R 316385 CDS YP_001729768.1 170080448 6061070 complement(875649..876890) 1 NC_010473.1 cardiolipin synthase 2 876890 ybhO 6061070 ybhO Escherichia coli str. K-12 substr. DH10B cardiolipin synthase 2 YP_001729768.1 875649 R 316385 CDS YP_001729769.1 170080449 6061064 complement(876887..877648) 1 NC_010473.1 DNase 877648 ybhP 6061064 ybhP Escherichia coli str. K-12 substr. DH10B DNase YP_001729769.1 876887 R 316385 CDS YP_001729770.1 170080450 6061077 877781..878191 1 NC_010473.1 inner membrane protein 878191 ybhQ 6061077 ybhQ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729770.1 877781 D 316385 CDS YP_001729771.1 170080451 6061047 complement(878153..879259) 1 NC_010473.1 ABC transporter membrane protein 879259 ybhR 6061047 ybhR Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001729771.1 878153 R 316385 CDS YP_001729772.1 170080452 6061052 complement(879270..880403) 1 NC_010473.1 ABC transporter membrane protein 880403 ybhS 6061052 ybhS Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001729772.1 879270 R 316385 CDS YP_001729773.1 170080453 6061046 complement(880396..882132) 1 NC_010473.1 ABC transporter ATP-binding protein 882132 ybhF 6061046 ybhF Escherichia coli str. K-12 substr. DH10B ABC transporter ATP-binding protein YP_001729773.1 880396 R 316385 CDS YP_001729774.1 170080454 6061054 complement(882125..883123) 1 NC_010473.1 hypothetical protein 883123 ybhG 6061054 ybhG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729774.1 882125 R 316385 CDS YP_001729775.1 170080455 6061091 complement(883123..883794) 1 NC_010473.1 putative DNA-binding transcriptional regulator 883794 ybiH 6061091 ybiH Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001729775.1 883123 R 316385 CDS YP_001729776.1 170080456 6061080 884023..885387 1 NC_010473.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 885387 rhlE 6061080 rhlE Escherichia coli str. K-12 substr. DH10B ATP-dependent RNA helicase RhlE YP_001729776.1 884023 D 316385 CDS YP_001729777.1 170080457 6061036 complement(885619..886101) 1 NC_010473.1 hypothetical protein 886101 ybiA 6061036 ybiA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729777.1 885619 R 316385 CDS YP_001729778.1 170080458 6061038 886221..888371 1 NC_010473.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 888371 dinG 6061038 dinG Escherichia coli str. K-12 substr. DH10B ATP-dependent DNA helicase DinG YP_001729778.1 886221 D 316385 CDS YP_001729779.1 170080459 6061032 888399..889361 1 NC_010473.1 glycosyl transferase family protein 889361 ybiB 6061032 ybiB Escherichia coli str. K-12 substr. DH10B glycosyl transferase family protein YP_001729779.1 888399 D 316385 CDS YP_001729780.1 170080460 6061035 889502..890587 1 NC_010473.1 hypothetical protein 890587 ybiC 6061035 ybiC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729780.1 889502 D 316385 CDS YP_001729781.1 170080461 6061042 complement(890816..891076) 1 NC_010473.1 hypothetical protein 891076 ybiJ 6061042 ybiJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729781.1 890816 R 316385 CDS YP_001729782.1 170080462 6061030 complement(891341..891607) 1 NC_010473.1 hypothetical protein 891607 ybiI 6061030 ybiI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729782.1 891341 R 316385 CDS YP_001729783.1 170080463 6061026 complement(891681..892358) 1 NC_010473.1 putative hydroxylase 892358 ybiX 6061026 ybiX Escherichia coli str. K-12 substr. DH10B putative hydroxylase YP_001729783.1 891681 R 316385 CDS YP_001729784.1 170080464 6061028 complement(892400..894682) 1 NC_010473.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 894682 fiu 6061028 fiu Escherichia coli str. K-12 substr. DH10B catecholate siderophore receptor Fiu YP_001729784.1 892400 R 316385 CDS YP_001729785.1 170080465 6061008 complement(894947..895207) 1 NC_010473.1 hypothetical protein 895207 ybiM 6061008 ybiM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729785.1 894947 R 316385 CDS YP_001729786.1 170080466 6061000 895483..896409 1 NC_010473.1 putative SAM-dependent methyltransferase 896409 ybiN 6061000 ybiN Escherichia coli str. K-12 substr. DH10B putative SAM-dependent methyltransferase YP_001729786.1 895483 D 316385 CDS YP_001729787.1 170080467 6061001 complement(896406..898631) 1 NC_010473.1 hypothetical protein 898631 ybiO 6061001 ybiO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729787.1 896406 R 316385 CDS YP_001729788.1 170080468 6060989 complement(898892..899614) 1 NC_010473.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 899614 glnQ 6060989 glnQ Escherichia coli str. K-12 substr. DH10B glutamine ABC transporter ATP-binding protein YP_001729788.1 898892 R 316385 CDS YP_001729789.1 170080469 6061003 complement(899611..900270) 1 NC_010473.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 900270 glnP 6061003 glnP Escherichia coli str. K-12 substr. DH10B glutamine ABC transporter permease YP_001729789.1 899611 R 316385 CDS YP_001729790.1 170080470 6060972 complement(900409..901155) 1 NC_010473.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 901155 glnH 6060972 glnH Escherichia coli str. K-12 substr. DH10B glutamine ABC transporter periplasmic protein YP_001729790.1 900409 R 316385 CDS YP_001729791.1 170080471 6060977 complement(901559..902062) 1 NC_010473.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 902062 dps 6060977 dps Escherichia coli str. K-12 substr. DH10B DNA starvation/stationary phase protection protein Dps YP_001729791.1 901559 R 316385 CDS YP_001729792.1 170080472 6060969 complement(902361..903248) 1 NC_010473.1 threonine and homoserine efflux system 903248 rhtA 6060969 rhtA Escherichia coli str. K-12 substr. DH10B threonine and homoserine efflux system YP_001729792.1 902361 R 316385 CDS YP_001729793.1 170080473 6060986 903601..904116 1 NC_010473.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 904116 ompX 6060986 ompX Escherichia coli str. K-12 substr. DH10B outer membrane protein X YP_001729793.1 903601 D 316385 CDS YP_001729794.1 170080474 6061029 complement(904165..905748) 1 NC_010473.1 hydrolase, inner membrane 905748 ybiP 6061029 ybiP Escherichia coli str. K-12 substr. DH10B hydrolase, inner membrane YP_001729794.1 904165 R 316385 CDS YP_001729795.1 170080475 6061023 905822..906091 1 NC_010473.1 hypothetical protein 906091 yliL 6061023 yliL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729795.1 905822 D 316385 CDS YP_001729796.1 170080476 6062164 906334..906801 1 NC_010473.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 906801 mntR 6062164 mntR Escherichia coli str. K-12 substr. DH10B manganese transport regulator MntR YP_001729796.1 906334 D 316385 CDS YP_001729797.1 170080477 6060959 906798..907916 1 NC_010473.1 transporter 907916 ybiR 6060959 ybiR Escherichia coli str. K-12 substr. DH10B transporter YP_001729797.1 906798 D 316385 CDS YP_001729798.1 170080478 6060945 complement(907975..908895) 1 NC_010473.1 hypothetical protein 908895 ybiS 6060945 ybiS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729798.1 907975 R 316385 CDS YP_001729799.1 170080479 6060949 909114..910706 1 NC_010473.1 ABC transporter ATP-binding protein 910706 ybiT 6060949 ybiT Escherichia coli str. K-12 substr. DH10B ABC transporter ATP-binding protein YP_001729799.1 909114 D 316385 CDS YP_001729800.1 170080480 6060960 complement(910947..912212) 1 NC_010473.1 hypothetical protein 912212 ybiU 6060960 ybiU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729800.1 910947 R 316385 CDS YP_001729801.1 170080481 6060942 complement(912364..913179) 1 NC_010473.1 hydrolase 913179 ybiV 6060942 ybiV Escherichia coli str. K-12 substr. DH10B hydrolase YP_001729801.1 912364 R 316385 CDS YP_001729802.1 170080482 6060936 complement(913325..915757) 1 NC_010473.1 pyruvate formate lyase 915757 ybiW 6060936 ybiW Escherichia coli str. K-12 substr. DH10B pyruvate formate lyase YP_001729802.1 913325 R 316385 CDS YP_001729803.1 170080483 6060937 complement(915763..916689) 1 NC_010473.1 pyruvate formate lyase activating enzyme 916689 ybiY 6060937 ybiY Escherichia coli str. K-12 substr. DH10B pyruvate formate lyase activating enzyme YP_001729803.1 915763 R 316385 CDS YP_001729804.1 170080484 6060929 916793..917455 1 NC_010473.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 917455 fsaA 6060929 fsaA Escherichia coli str. K-12 substr. DH10B fructose-6-phosphate aldolase YP_001729804.1 916793 D 316385 CDS YP_001729805.1 170080485 6060922 complement(917531..918280) 1 NC_010473.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 918280 moeB 6060922 moeB Escherichia coli str. K-12 substr. DH10B molybdopterin biosynthesis protein MoeB YP_001729805.1 917531 R 316385 CDS YP_001729806.1 170080486 6060923 complement(918280..919515) 1 NC_010473.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 919515 moeA 6060923 moeA Escherichia coli str. K-12 substr. DH10B molybdopterin biosynthesis protein MoeA YP_001729806.1 918280 R 316385 CDS YP_001729807.1 170080487 6060921 919719..920684 1 NC_010473.1 L-asparaginase 920684 iaaA 6060921 iaaA Escherichia coli str. K-12 substr. DH10B L-asparaginase YP_001729807.1 919719 D 316385 CDS YP_001729808.1 170080488 6060924 920671..922542 1 NC_010473.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 922542 gsiA 6060924 gsiA Escherichia coli str. K-12 substr. DH10B glutathione transporter ATP-binding protein YP_001729808.1 920671 D 316385 CDS YP_001729809.1 170080489 6060911 922562..924100 1 NC_010473.1 periplasmic solute-binding component of a glutathione transporter 924100 gsiB 6060911 gsiB Escherichia coli str. K-12 substr. DH10B periplasmic solute-binding component of a glutathione transporter YP_001729809.1 922562 D 316385 CDS YP_001729810.1 170080490 6060913 924118..925038 1 NC_010473.1 permease component of a glutathione transporter 925038 gsiC 6060913 gsiC Escherichia coli str. K-12 substr. DH10B permease component of a glutathione transporter YP_001729810.1 924118 D 316385 CDS YP_001729811.1 170080491 6060909 925041..925952 1 NC_010473.1 permease component of a glutathione transporter 925952 gsiD 6060909 gsiD Escherichia coli str. K-12 substr. DH10B permease component of a glutathione transporter YP_001729811.1 925041 D 316385 CDS YP_001729812.1 170080492 6060915 926130..928478 1 NC_010473.1 inner membrane protein 928478 yliE 6060915 yliE Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729812.1 926130 D 316385 CDS YP_001729813.1 170080493 6060939 928486..929814 1 NC_010473.1 diguanylate cyclase 929814 yliF 6060939 yliF Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001729813.1 928486 D 316385 CDS YP_001729814.1 170080494 6060931 complement(929861..931186) 1 NC_010473.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 931186 rimO 6060931 rimO Escherichia coli str. K-12 substr. DH10B ribosomal protein S12 methylthiotransferase YP_001729814.1 929861 R 316385 CDS YP_001729815.1 170080495 6060885 931399..931782 1 NC_010473.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 931782 bssR 6060885 bssR Escherichia coli str. K-12 substr. DH10B biofilm formation regulatory protein BssR YP_001729815.1 931399 D 316385 CDS YP_001729816.1 170080496 6060888 931893..933008 1 NC_010473.1 dehydrogenase 933008 yliI 6060888 yliI Escherichia coli str. K-12 substr. DH10B dehydrogenase YP_001729816.1 931893 D 316385 CDS YP_001729817.1 170080497 6060876 complement(933005..933631) 1 NC_010473.1 glutathione S-transferase 933631 yliJ 6060876 yliJ Escherichia coli str. K-12 substr. DH10B glutathione S-transferase YP_001729817.1 933005 R 316385 CDS YP_001729818.1 170080498 6060877 933878..935080 1 NC_010473.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 935080 dacC 6060877 dacC Escherichia coli str. K-12 substr. DH10B D-alanyl-D-alanine carboxypeptidase YP_001729818.1 933878 D 316385 CDS YP_001729819.1 170080499 6060906 complement(935127..935885) 1 NC_010473.1 DNA-binding transcriptional repressor DeoR 935885 deoR 6060906 deoR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor DeoR YP_001729819.1 935127 R 316385 CDS YP_001729820.1 170080500 6060873 complement(935943..936539) 1 NC_010473.1 undecaprenyl pyrophosphate phosphatase 936539 ybjG 6060873 ybjG Escherichia coli str. K-12 substr. DH10B undecaprenyl pyrophosphate phosphatase YP_001729820.1 935943 R 316385 CDS YP_001729821.1 170080501 6060869 936824..938056 1 NC_010473.1 multidrug efflux system protein 938056 cmr 6060869 cmr Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein YP_001729821.1 936824 D 316385 CDS YP_001729822.1 170080502 6060871 complement(938097..938381) 1 NC_010473.1 hypothetical protein 938381 ybjH 6060871 ybjH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729822.1 938097 R 316385 CDS YP_001729823.1 170080503 6060860 complement(938467..939282) 1 NC_010473.1 hypothetical protein 939282 ybjI 6060860 ybjI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729823.1 938467 R 316385 CDS YP_001729824.1 170080504 6060845 complement(939282..940490) 1 NC_010473.1 transporter 940490 ybjJ 6060845 ybjJ Escherichia coli str. K-12 substr. DH10B transporter YP_001729824.1 939282 R 316385 CDS YP_001729825.1 170080505 6060850 940574..941110 1 NC_010473.1 DNA-binding transcriptional regulator 941110 ybjK 6060850 ybjK Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729825.1 940574 D 316385 CDS YP_001729826.1 170080506 6058171 complement(941285..942970) 1 NC_010473.1 hypothetical protein 942970 ybjL 6058171 ybjL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729826.1 941285 R 316385 CDS YP_001729827.1 170080507 6060854 943240..943617 1 NC_010473.1 inner membrane protein 943617 ybjM 6060854 ybjM Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729827.1 943240 D 316385 CDS YP_001729828.1 170080508 6060838 complement(943647..943904) 1 NC_010473.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 943904 grxA 6060838 grxA Escherichia coli str. K-12 substr. DH10B glutaredoxin YP_001729828.1 943647 R 316385 CDS YP_001729829.1 170080509 6060841 944064..944351 1 NC_010473.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 944351 ybjC 6060841 ybjC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729829.1 944064 D 316385 CDS YP_001729830.1 170080510 6060833 944335..945057 1 NC_010473.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 945057 nfsA 6060833 nfsA Escherichia coli str. K-12 substr. DH10B nitroreductase A YP_001729830.1 944335 D 316385 CDS YP_001729831.1 170080511 6060843 945118..946020 1 NC_010473.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 946020 rimK 6060843 rimK Escherichia coli str. K-12 substr. DH10B ribosomal protein S6 modification protein YP_001729831.1 945118 D 316385 CDS YP_001729832.1 170080512 6060872 946108..946584 1 NC_010473.1 oxidoreductase 946584 ybjN 6060872 ybjN Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001729832.1 946108 D 316385 CDS YP_001729833.1 170080513 6060864 946935..948047 1 NC_010473.1 putrescine ABC transporter periplasmic-binding protein 948047 potF 6060864 potF Escherichia coli str. K-12 substr. DH10B putrescine ABC transporter periplasmic-binding protein YP_001729833.1 946935 D 316385 CDS YP_001729834.1 170080514 6060826 948142..949275 1 NC_010473.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 949275 potG 6060826 potG Escherichia coli str. K-12 substr. DH10B putrescine ABC transporter ATP-binding protein YP_001729834.1 948142 D 316385 CDS YP_001729835.1 170080515 6060827 949285..950238 1 NC_010473.1 putrescine ABC transporter membrane protein 950238 potH 6060827 potH Escherichia coli str. K-12 substr. DH10B putrescine ABC transporter membrane protein YP_001729835.1 949285 D 316385 CDS YP_001729836.1 170080516 6060821 950235..951080 1 NC_010473.1 putrescine ABC transporter membrane protein 951080 potI 6060821 potI Escherichia coli str. K-12 substr. DH10B putrescine ABC transporter membrane protein YP_001729836.1 950235 D 316385 CDS YP_001729837.1 170080517 6060822 951140..951628 1 NC_010473.1 inner membrane protein 951628 ybjO 6060822 ybjO Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729837.1 951140 D 316385 CDS YP_001729838.1 170080518 6060828 951669..952796 1 NC_010473.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 952796 rumB 6060828 rumB Escherichia coli str. K-12 substr. DH10B 23S rRNA methyluridine methyltransferase YP_001729838.1 951669 D 316385 CDS YP_001729839.1 170080519 6060820 complement(952995..953726) 1 NC_010473.1 arginine ABC transporter periplasmic-binding protein 953726 artJ 6060820 artJ Escherichia coli str. K-12 substr. DH10B arginine ABC transporter periplasmic-binding protein YP_001729839.1 952995 R 316385 CDS YP_001729840.1 170080520 6060813 complement(954017..954685) 1 NC_010473.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 954685 artM 6060813 artM Escherichia coli str. K-12 substr. DH10B arginine transporter permease subunit ArtM YP_001729840.1 954017 R 316385 CDS YP_001729841.1 170080521 6060818 complement(954685..955401) 1 NC_010473.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 955401 artQ 6060818 artQ Escherichia coli str. K-12 substr. DH10B arginine transporter permease subunit ArtQ YP_001729841.1 954685 R 316385 CDS YP_001729842.1 170080522 6060809 complement(955408..956139) 1 NC_010473.1 arginine ABC transporter periplasmic-binding protein 956139 artI 6060809 artI Escherichia coli str. K-12 substr. DH10B arginine ABC transporter periplasmic-binding protein YP_001729842.1 955408 R 316385 CDS YP_001729843.1 170080523 6060802 complement(956157..956885) 1 NC_010473.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 956885 artP 6060802 artP Escherichia coli str. K-12 substr. DH10B arginine transporter ATP-binding subunit YP_001729843.1 956157 R 316385 CDS YP_001729844.1 170080524 6060804 complement(957103..957618) 1 NC_010473.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein 957618 ybjP 6060804 ybjP Escherichia coli str. K-12 substr. DH10B putative lipoprotein YP_001729844.1 957103 R 316385 CDS YP_001729845.1 170080525 6060801 957744..958067 1 NC_010473.1 hypothetical protein 958067 ybjQ 6060801 ybjQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729845.1 957744 D 316385 CDS YP_001729846.1 170080526 6060805 958064..958894 1 NC_010473.1 amidase 958894 ybjR 6060805 ybjR Escherichia coli str. K-12 substr. DH10B amidase YP_001729846.1 958064 D 316385 CDS YP_001729847.1 170080527 6060797 complement(958891..959904) 1 NC_010473.1 NAD(P)-binding oxidoreductase 959904 ybjS 6060797 ybjS Escherichia coli str. K-12 substr. DH10B NAD(P)-binding oxidoreductase YP_001729847.1 958891 R 316385 CDS YP_001729848.1 170080528 6060799 complement(960003..961433) 1 NC_010473.1 hypothetical protein 961433 ybjT 6060799 ybjT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729848.1 960003 R 316385 CDS YP_001729849.1 170080529 6060796 complement(961444..962445) 1 NC_010473.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 962445 ltaE 6060796 ltaE Escherichia coli str. K-12 substr. DH10B L-threonine aldolase YP_001729849.1 961444 R 316385 CDS YP_001729850.1 170080530 6060800 complement(962482..964200) 1 NC_010473.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 964200 poxB 6060800 poxB Escherichia coli str. K-12 substr. DH10B pyruvate dehydrogenase YP_001729850.1 962482 R 316385 CDS YP_001729851.1 170080531 6060819 complement(964333..965301) 1 NC_010473.1 HCP oxidoreductase 965301 hcr 6060819 hcr Escherichia coli str. K-12 substr. DH10B HCP oxidoreductase YP_001729851.1 964333 R 316385 CDS YP_001729852.1 170080532 6060812 complement(965313..966965) 1 NC_010473.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 966965 hcp 6060812 hcp Escherichia coli str. K-12 substr. DH10B hydroxylamine reductase YP_001729852.1 965313 R 316385 CDS YP_001729853.1 170080533 6060785 complement(967109..968008) 1 NC_010473.1 transporter 968008 ybjE 6060785 ybjE Escherichia coli str. K-12 substr. DH10B transporter YP_001729853.1 967109 R 316385 CDS YP_001729854.1 170080534 6060786 complement(968503..969198) 1 NC_010473.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 969198 aqpZ 6060786 aqpZ Escherichia coli str. K-12 substr. DH10B aquaporin Z YP_001729854.1 968503 R 316385 CDS YP_001729855.1 170080535 6060777 969624..971282 1 NC_010473.1 contains the nonsynonymous change M498I; hypothetical protein 971282 ybjD 6060777 ybjD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729855.1 969624 D 316385 CDS YP_001729856.1 170080536 6060781 complement(971279..972271) 1 NC_010473.1 hypothetical protein 972271 ybjX 6060781 ybjX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729856.1 971279 R 316385 CDS YP_001729857.1 170080537 6060793 972386..973501 1 NC_010473.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 973501 macA 6060793 macA Escherichia coli str. K-12 substr. DH10B macrolide transporter subunit MacA YP_001729857.1 972386 D 316385 CDS YP_001729858.1 170080538 6060774 973498..975444 1 NC_010473.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 975444 macB 6060774 macB Escherichia coli str. K-12 substr. DH10B macrolide transporter ATP-binding /permease YP_001729858.1 973498 D 316385 CDS YP_001729859.1 170080539 6060768 complement(975517..975741) 1 NC_010473.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 975741 cspD 6060768 cspD Escherichia coli str. K-12 substr. DH10B stationary phase/starvation inducible regulatory protein CspD YP_001729859.1 975517 R 316385 CDS YP_001729860.1 170080540 6060769 976064..976384 1 NC_010473.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 976384 clpS 6060769 clpS Escherichia coli str. K-12 substr. DH10B ATP-dependent Clp protease adaptor protein ClpS YP_001729860.1 976064 D 316385 CDS YP_001729861.1 170080541 6060764 976415..978691 1 NC_010473.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 978691 clpA 6060764 clpA Escherichia coli str. K-12 substr. DH10B ATP-dependent Clp protease ATP-binding subunit YP_001729861.1 976415 D 316385 CDS YP_001729862.1 170080542 6059392 complement(979376..979594) 1 NC_010473.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 979594 infA 6059392 infA Escherichia coli str. K-12 substr. DH10B translation initiation factor IF-1 YP_001729862.1 979376 R 316385 CDS YP_001729863.1 170080543 6060751 complement(979879..980583) 1 NC_010473.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 980583 aat 6060751 aat Escherichia coli str. K-12 substr. DH10B leucyl/phenylalanyl-tRNA--protein transferase YP_001729863.1 979879 R 316385 CDS YP_001729864.1 170080544 6060747 complement(980625..982346) 1 NC_010473.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 982346 cydC 6060747 cydC Escherichia coli str. K-12 substr. DH10B cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001729864.1 980625 R 316385 CDS YP_001729865.1 170080545 6060755 complement(982347..984113) 1 NC_010473.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 984113 cydD 6060755 cydD Escherichia coli str. K-12 substr. DH10B cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001729865.1 982347 R 316385 CDS YP_001729866.1 170080546 6060711 complement(984236..985201) 1 NC_010473.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 985201 trxB 6060711 trxB Escherichia coli str. K-12 substr. DH10B thioredoxin reductase YP_001729866.1 984236 R 316385 CDS YP_001729867.1 170080547 6060741 985746..986240 1 NC_010473.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 986240 lrp 6060741 lrp Escherichia coli str. K-12 substr. DH10B leucine-responsive transcriptional regulator YP_001729867.1 985746 D 316385 CDS YP_001729868.1 170080548 6060702 986375..990364 1 NC_010473.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 990364 ftsK 6060702 ftsK Escherichia coli str. K-12 substr. DH10B DNA translocase FtsK YP_001729868.1 986375 D 316385 CDS YP_001729869.1 170080549 6060745 990523..991134 1 NC_010473.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 991134 lolA 6060745 lolA Escherichia coli str. K-12 substr. DH10B outer-membrane lipoprotein carrier protein YP_001729869.1 990523 D 316385 CDS YP_001729870.1 170080550 6060771 991145..992488 1 NC_010473.1 recombination factor protein RarA 992488 ycaJ 6060771 ycaJ Escherichia coli str. K-12 substr. DH10B recombination factor protein RarA YP_001729870.1 991145 D 316385 CDS YP_001729871.1 170080551 6060765 992579..993871 1 NC_010473.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 993871 serS 6060765 serS Escherichia coli str. K-12 substr. DH10B seryl-tRNA synthetase YP_001729871.1 992579 D 316385 CDS YP_001729872.1 170080552 6060687 994110..996554 1 NC_010473.1 dimethyl sulfoxide reductase, anaerobic subunit A 996554 dmsA 6060687 dmsA Escherichia coli str. K-12 substr. DH10B dimethyl sulfoxide reductase, anaerobic subunit A YP_001729872.1 994110 D 316385 CDS YP_001729873.1 170080553 6060692 996565..997182 1 NC_010473.1 dimethyl sulfoxide reductase, anaerobic subunit B 997182 dmsB 6060692 dmsB Escherichia coli str. K-12 substr. DH10B dimethyl sulfoxide reductase, anaerobic subunit B YP_001729873.1 996565 D 316385 CDS YP_001729874.1 170080554 6060685 997184..998047 1 NC_010473.1 dimethyl sulfoxide reductase, anaerobic subunit C 998047 dmsC 6060685 dmsC Escherichia coli str. K-12 substr. DH10B dimethyl sulfoxide reductase, anaerobic subunit C YP_001729874.1 997184 D 316385 CDS YP_001729875.1 170080555 6060686 complement(998082..998708) 1 NC_010473.1 hydrolase 998708 ycaC 6060686 ycaC Escherichia coli str. K-12 substr. DH10B hydrolase YP_001729875.1 998082 R 316385 CDS YP_001729876.1 170080556 6060700 999022..1000170 1 NC_010473.1 putative MFS family transporter protein 1000170 ycaD 6060700 ycaD Escherichia coli str. K-12 substr. DH10B putative MFS family transporter protein YP_001729876.1 999022 D 316385 CDS YP_001729877.1 170080557 6060668 1000380..1001810 1 NC_010473.1 transporter 1001810 ycaM 6060668 ycaM Escherichia coli str. K-12 substr. DH10B transporter YP_001729877.1 1000380 D 316385 CDS YP_001729878.1 170080558 6060656 complement(1001811..1002719) 1 NC_010473.1 DNA-binding transcriptional regulator 1002719 ycaN 6060656 ycaN Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001729878.1 1001811 R 316385 CDS YP_001729879.1 170080559 6060658 1002819..1003409 1 NC_010473.1 hypothetical protein 1003409 ycaK 6060658 ycaK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729879.1 1002819 D 316385 CDS YP_001729880.1 170080560 6060644 complement(1003491..1004231) 1 NC_010473.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1004231 pflA 6060644 pflA Escherichia coli str. K-12 substr. DH10B pyruvate formate lyase-activating enzyme 1 YP_001729880.1 1003491 R 316385 CDS YP_001729881.1 170080561 6060638 complement(1004423..1006705) 1 NC_010473.1 pyruvate formate lyase I 1006705 pflB 6060638 pflB Escherichia coli str. K-12 substr. DH10B pyruvate formate lyase I YP_001729881.1 1004423 R 316385 CDS YP_001729882.1 170080562 6060640 complement(1006760..1007617) 1 NC_010473.1 formate transporter 1007617 focA 6060640 focA Escherichia coli str. K-12 substr. DH10B formate transporter YP_001729882.1 1006760 R 316385 CDS YP_001729883.1 170080563 6060634 complement(1008023..1009783) 1 NC_010473.1 hypothetical protein 1009783 ycaO 6060634 ycaO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729883.1 1008023 R 316385 CDS YP_001729884.1 170080564 6060641 1009913..1010605 1 NC_010473.1 inner membrane protein 1010605 ycaP 6060641 ycaP Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729884.1 1009913 D 316385 CDS YP_001729885.1 170080565 6060653 1010804..1011892 1 NC_010473.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1011892 serC 6060653 serC Escherichia coli str. K-12 substr. DH10B phosphoserine aminotransferase YP_001729885.1 1010804 D 316385 CDS YP_001729886.1 170080566 6060621 1011963..1013246 1 NC_010473.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1013246 aroA 6060621 aroA Escherichia coli str. K-12 substr. DH10B 3-phosphoshikimate 1-carboxyvinyltransferase YP_001729886.1 1011963 D 316385 CDS YP_001729887.1 170080567 6060626 1013415..1014179 1 NC_010473.1 peptidase with chaperone function 1014179 ycaL 6060626 ycaL Escherichia coli str. K-12 substr. DH10B peptidase with chaperone function YP_001729887.1 1013415 D 316385 CDS YP_001729888.1 170080568 6060620 1014352..1015035 1 NC_010473.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1015035 cmk 6060620 cmk Escherichia coli str. K-12 substr. DH10B cytidylate kinase YP_001729888.1 1014352 D 316385 CDS YP_001729889.1 170080569 6060632 1015146..1016819 1 NC_010473.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1016819 rpsA 6060632 rpsA Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S1 YP_001729889.1 1015146 D 316385 CDS YP_001729890.1 170080570 6060662 1016979..1017263 1 NC_010473.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1017263 ihfB 6060662 ihfB Escherichia coli str. K-12 substr. DH10B integration host factor subunit beta YP_001729890.1 1016979 D 316385 CDS YP_001729891.1 170080571 6060650 1017471..1019735 1 NC_010473.1 hypothetical protein 1019735 ycaI 6060650 ycaI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729891.1 1017471 D 316385 CDS YP_001729892.1 170080572 6062280 1019772..1021520 1 NC_010473.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1021520 msbA 6062280 msbA Escherichia coli str. K-12 substr. DH10B lipid transporter ATP-binding/permease YP_001729892.1 1019772 D 316385 CDS YP_001729893.1 170080573 6060588 1021517..1022503 1 NC_010473.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1022503 lpxK 6060588 lpxK Escherichia coli str. K-12 substr. DH10B tetraacyldisaccharide 4'-kinase YP_001729893.1 1021517 D 316385 CDS YP_001729894.1 170080574 6060592 1022540..1023772 1 NC_010473.1 hypothetical protein 1023772 ycaQ 6060592 ycaQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729894.1 1022540 D 316385 CDS YP_001729895.1 170080575 6060583 1023824..1024006 1 NC_010473.1 hypothetical protein 1024006 ycaR 6060583 ycaR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729895.1 1023824 D 316385 CDS YP_001729896.1 170080576 6060586 1024003..1024749 1 NC_010473.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1024749 kdsB 6060586 kdsB Escherichia coli str. K-12 substr. DH10B 3-deoxy-manno-octulosonate cytidylyltransferase YP_001729896.1 1024003 D 316385 CDS YP_001729897.1 170080577 6060612 1024903..1025796 1 NC_010473.1 hypothetical protein 1025796 ycbJ 6060612 ycbJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729897.1 1024903 D 316385 CDS YP_001729898.1 170080578 6060581 complement(1025773..1026552) 1 NC_010473.1 hypothetical protein 1026552 ycbC 6060581 ycbC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729898.1 1025773 R 316385 CDS YP_001729899.1 170080579 6060571 1026688..1027473 1 NC_010473.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 1027473 smtA 6060571 smtA Escherichia coli str. K-12 substr. DH10B putative metallothionein SmtA YP_001729899.1 1026688 D 316385 CDS YP_001729900.1 170080580 6060574 1027470..1028792 1 NC_010473.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1028792 mukF 6060574 mukF Escherichia coli str. K-12 substr. DH10B condesin subunit F YP_001729900.1 1027470 D 316385 CDS YP_001729901.1 170080581 6060563 1028800..1029477 1 NC_010473.1 protein involved in chromosome partitioning; acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1029477 mukE 6060563 mukE Escherichia coli str. K-12 substr. DH10B condesin subunit E YP_001729901.1 1028800 D 316385 CDS YP_001729902.1 170080582 6060547 1029477..1033937 1 NC_010473.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1033937 mukB 6060547 mukB Escherichia coli str. K-12 substr. DH10B cell division protein MukB YP_001729902.1 1029477 D 316385 CDS YP_001729903.1 170080583 6060557 1034198..1036045 1 NC_010473.1 hypothetical protein 1036045 ycbB 6060557 ycbB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729903.1 1034198 D 316385 CDS YP_001729904.1 170080584 6060546 1036226..1036774 1 NC_010473.1 hypothetical protein 1036774 ycbK 6060546 ycbK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729904.1 1036226 D 316385 CDS YP_001729905.1 170080585 6060562 1036801..1037448 1 NC_010473.1 metal-binding protein 1037448 ycbL 6060562 ycbL Escherichia coli str. K-12 substr. DH10B metal-binding protein YP_001729905.1 1036801 D 316385 CDS YP_001729906.1 170080586 6060534 complement(1037670..1038860) 1 NC_010473.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1038860 aspC 6060534 aspC Escherichia coli str. K-12 substr. DH10B aromatic amino acid aminotransferase YP_001729906.1 1037670 R 316385 CDS YP_001729907.1 170080587 6060536 complement(1039045..1040133) 1 NC_010473.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 1040133 ompF 6060536 ompF Escherichia coli str. K-12 substr. DH10B outer membrane protein F YP_001729907.1 1039045 R 316385 CDS YP_001729908.1 170080588 6060533 complement(1040736..1042136) 1 NC_010473.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1042136 asnC 6060533 asnC Escherichia coli str. K-12 substr. DH10B asparaginyl-tRNA synthetase YP_001729908.1 1040736 R 316385 CDS YP_001729909.1 170080589 6060538 complement(1042305..1043507) 1 NC_010473.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1043507 pncB 6060538 pncB Escherichia coli str. K-12 substr. DH10B nicotinate phosphoribosyltransferase YP_001729909.1 1042305 R 316385 CDS YP_001729910.1 170080590 6060577 1043773..1046385 1 NC_010473.1 aminopeptidase N 1046385 pepN 6060577 pepN Escherichia coli str. K-12 substr. DH10B aminopeptidase N YP_001729910.1 1043773 D 316385 CDS YP_001729911.1 170080591 6060568 complement(1046428..1047195) 1 NC_010473.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1047195 ssuB 6060568 ssuB Escherichia coli str. K-12 substr. DH10B aliphatic sulfonates transport ATP-binding subunit YP_001729911.1 1046428 R 316385 CDS YP_001729912.1 170080592 6060509 complement(1047192..1047983) 1 NC_010473.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease 1047983 ssuC 6060509 ssuC Escherichia coli str. K-12 substr. DH10B alkanesulfonate transporter permease YP_001729912.1 1047192 R 316385 CDS YP_001729913.1 170080593 6060526 complement(1047994..1049139) 1 NC_010473.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1049139 ssuD 6060526 ssuD Escherichia coli str. K-12 substr. DH10B alkanesulfonate monooxygenase YP_001729913.1 1047994 R 316385 CDS YP_001729914.1 170080594 6060500 complement(1049136..1050095) 1 NC_010473.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1050095 ssuA 6060500 ssuA Escherichia coli str. K-12 substr. DH10B alkanesulfonate transporter substrate-binding subunit YP_001729914.1 1049136 R 316385 CDS YP_001729915.1 170080595 6060504 complement(1050088..1050663) 1 NC_010473.1 NAD(P)H-dependent FMN reductase 1050663 ssuE 6060504 ssuE Escherichia coli str. K-12 substr. DH10B NAD(P)H-dependent FMN reductase YP_001729915.1 1050088 R 316385 CDS YP_001729916.1 170080596 6060532 1051019..1051558 1 NC_010473.1 fimbrial-like adhesin protein 1051558 ycbQ 6060532 ycbQ Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729916.1 1051019 D 316385 CDS YP_001729917.1 170080597 6060476 1051641..1052342 1 NC_010473.1 periplasmic pilin chaperone 1052342 ycbR 6060476 ycbR Escherichia coli str. K-12 substr. DH10B periplasmic pilin chaperone YP_001729917.1 1051641 D 316385 CDS YP_001729918.1 170080598 6060461 1052367..1054967 1 NC_010473.1 outer membrane usher protein 1054967 ycbS 6060461 ycbS Escherichia coli str. K-12 substr. DH10B outer membrane usher protein YP_001729918.1 1052367 D 316385 CDS YP_001729919.1 170080599 6060463 1054958..1056028 1 NC_010473.1 fimbrial-like adhesin protein 1056028 ycbT 6060463 ycbT Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729919.1 1054958 D 316385 CDS YP_001729920.1 170080600 6060380 1056040..1056582 1 NC_010473.1 contains the nonsynonymous change G119W; fimbrial-like adhesin protein 1056582 ycbU 6060380 ycbU Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729920.1 1056040 D 316385 CDS YP_001729921.1 170080601 6060374 1056590..1057105 1 NC_010473.1 fimbrial-like adhesin protein 1057105 ycbV 6060374 ycbV Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001729921.1 1056590 D 316385 CDS YP_001729922.1 170080602 6060375 1057098..1057808 1 NC_010473.1 pili assembly chaperone 1057808 ycbF 6060375 ycbF Escherichia coli str. K-12 substr. DH10B pili assembly chaperone YP_001729922.1 1057098 D 316385 CDS YP_001729923.1 170080603 6060372 1057919..1058929 1 NC_010473.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1058929 pyrD 6060372 pyrD Escherichia coli str. K-12 substr. DH10B dihydroorotate dehydrogenase 2 YP_001729923.1 1057919 D 316385 CDS YP_001729924.1 170080604 6060379 1059103..1059645 1 NC_010473.1 hypothetical protein 1059645 ycbW 6060379 ycbW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729924.1 1059103 D 316385 CDS YP_001729925.1 170080605 6060340 complement(1059642..1060751) 1 NC_010473.1 2Fe-2S cluster-containing protein 1060751 ycbX 6060340 ycbX Escherichia coli str. K-12 substr. DH10B 2Fe-2S cluster-containing protein YP_001729925.1 1059642 R 316385 CDS YP_001729926.1 170080606 6060358 1060995..1063103 1 NC_010473.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1063103 rlmL 6060358 rlmL Escherichia coli str. K-12 substr. DH10B 23S rRNA m(2)G2445 methyltransferase YP_001729926.1 1060995 D 316385 CDS YP_001729927.1 170080607 6060338 1063115..1065022 1 NC_010473.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1065022 uup 6060338 uup Escherichia coli str. K-12 substr. DH10B ABC transporter ATPase YP_001729927.1 1063115 D 316385 CDS YP_001729928.1 170080608 6060365 1065152..1066405 1 NC_010473.1 paraquat-inducible membrane protein A 1066405 pqiA 6060365 pqiA Escherichia coli str. K-12 substr. DH10B paraquat-inducible membrane protein A YP_001729928.1 1065152 D 316385 CDS YP_001729929.1 170080609 6060396 1066410..1068050 1 NC_010473.1 paraquat-inducible protein B 1068050 pqiB 6060396 pqiB Escherichia coli str. K-12 substr. DH10B paraquat-inducible protein B YP_001729929.1 1066410 D 316385 CDS YP_001729930.1 170080610 6060464 1068047..1068610 1 NC_010473.1 hypothetical protein 1068610 ymbA 6060464 ymbA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729930.1 1068047 D 316385 CDS YP_001729931.1 170080611 6060400 1068866..1069033 1 NC_010473.1 ribosome modulation factor 1069033 rmf 6060400 rmf Escherichia coli str. K-12 substr. DH10B ribosome modulation factor YP_001729931.1 1068866 D 316385 CDS YP_001729932.1 170080612 6060334 complement(1069103..1069621) 1 NC_010473.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1069621 fabA 6060334 fabA Escherichia coli str. K-12 substr. DH10B 3-hydroxydecanoyl-ACP dehydratase YP_001729932.1 1069103 R 316385 CDS YP_001729933.1 170080613 6060335 complement(1069690..1071450) 1 NC_010473.1 peptidase 1071450 ycbZ 6060335 ycbZ Escherichia coli str. K-12 substr. DH10B peptidase YP_001729933.1 1069690 R 316385 CDS YP_001729934.1 170080614 6060326 1071636..1072088 1 NC_010473.1 hypothetical protein 1072088 ycbG 6060326 ycbG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729934.1 1071636 D 316385 CDS YP_001729935.1 170080615 6060328 complement(1072164..1073204) 1 NC_010473.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1073204 ompA 6060328 ompA Escherichia coli str. K-12 substr. DH10B outer membrane protein A YP_001729935.1 1072164 R 316385 CDS YP_001729936.1 170080616 6060336 complement(1073561..1074070) 1 NC_010473.1 SOS cell division inhibitor 1074070 sulA 6060336 sulA Escherichia coli str. K-12 substr. DH10B SOS cell division inhibitor YP_001729936.1 1073561 R 316385 CDS YP_001729937.1 170080617 6060320 1074289..1074918 1 NC_010473.1 CRP-S promoter co-activator 1074918 sxy 6060320 sxy Escherichia coli str. K-12 substr. DH10B CRP-S promoter co-activator YP_001729937.1 1074289 D 316385 CDS YP_001729938.1 170080618 6060293 complement(1074881..1077034) 1 NC_010473.1 inner membrane protein 1077034 yccS 6060293 yccS Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001729938.1 1074881 R 316385 CDS YP_001729939.1 170080619 6060300 complement(1077053..1077499) 1 NC_010473.1 hypothetical protein 1077499 yccF 6060300 yccF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729939.1 1077053 R 316385 CDS YP_001729940.1 170080620 6060264 1077622..1079676 1 NC_010473.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1079676 helD 6060264 helD Escherichia coli str. K-12 substr. DH10B DNA helicase IV YP_001729940.1 1077622 D 316385 CDS YP_001729941.1 170080621 6060225 complement(1079708..1080166) 1 NC_010473.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1080166 mgsA 6060225 mgsA Escherichia coli str. K-12 substr. DH10B methylglyoxal synthase YP_001729941.1 1079708 R 316385 CDS YP_001729942.1 170080622 6060250 complement(1080262..1080924) 1 NC_010473.1 hypothetical protein 1080924 yccT 6060250 yccT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729942.1 1080262 R 316385 CDS YP_001729943.1 170080623 6060224 1081097..1081510 1 NC_010473.1 CoA-binding protein 1081510 yccU 6060224 yccU Escherichia coli str. K-12 substr. DH10B CoA-binding protein YP_001729943.1 1081097 D 316385 CDS YP_001729944.1 170080624 6060257 complement(1081555..1081872) 1 NC_010473.1 heat shock protein HspQ 1081872 hspQ 6060257 hspQ Escherichia coli str. K-12 substr. DH10B heat shock protein HspQ YP_001729944.1 1081555 R 316385 CDS YP_001729945.1 170080625 6060205 complement(1081930..1083120) 1 NC_010473.1 methyltransferase 1083120 yccW 6060205 yccW Escherichia coli str. K-12 substr. DH10B methyltransferase YP_001729945.1 1081930 R 316385 CDS YP_001729946.1 170080626 6060211 1083215..1083493 1 NC_010473.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1083493 yccX 6060211 yccX Escherichia coli str. K-12 substr. DH10B acylphosphatase YP_001729946.1 1083215 D 316385 CDS YP_001729947.1 170080627 6060203 complement(1083490..1083819) 1 NC_010473.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1083819 yccK 6060203 yccK Escherichia coli str. K-12 substr. DH10B sulfur transfer protein TusE YP_001729947.1 1083490 R 316385 CDS YP_001729948.1 170080628 6060215 complement(1083910..1084569) 1 NC_010473.1 hypothetical protein 1084569 yccA 6060215 yccA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729948.1 1083910 R 316385 CDS YP_001729949.1 170080629 6060551 1085290..1086408 1 NC_010473.1 hydrogenase 1, small subunit 1086408 hyaA 6060551 hyaA Escherichia coli str. K-12 substr. DH10B hydrogenase 1, small subunit YP_001729949.1 1085290 D 316385 CDS YP_001729950.1 170080630 6060289 1086405..1088198 1 NC_010473.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1088198 hyaB 6060289 hyaB Escherichia coli str. K-12 substr. DH10B hydrogenase 1 large subunit YP_001729950.1 1086405 D 316385 CDS YP_001729951.1 170080631 6060173 1088217..1088924 1 NC_010473.1 hydrogenase 1 b-type cytochrome subunit 1088924 hyaC 6060173 hyaC Escherichia coli str. K-12 substr. DH10B hydrogenase 1 b-type cytochrome subunit YP_001729951.1 1088217 D 316385 CDS YP_001729952.1 170080632 6060182 1088921..1089508 1 NC_010473.1 protein involved in processing of HyaA and HyaB proteins; HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1089508 hyaD 6060182 hyaD Escherichia coli str. K-12 substr. DH10B hydrogenase 1 maturation protease YP_001729952.1 1088921 D 316385 CDS YP_001729953.1 170080633 6060159 1089505..1089903 1 NC_010473.1 protein involved in processing of HyaA and HyaB proteins; involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1089903 hyaE 6060159 hyaE Escherichia coli str. K-12 substr. DH10B hydrogenase-1 operon protein HyaE YP_001729953.1 1089505 D 316385 CDS YP_001729954.1 170080634 6060164 1089900..1090757 1 NC_010473.1 protein involved in nickel incorporation into hydrogenase-1 proteins; protein HyaF 1090757 hyaF 6060164 hyaF Escherichia coli str. K-12 substr. DH10B protein HyaF YP_001729954.1 1089900 D 316385 CDS YP_001729955.1 170080635 6060199 1090891..1092435 1 NC_010473.1 cytochrome bd-II oxidase subunit I 1092435 appC 6060199 appC Escherichia coli str. K-12 substr. DH10B cytochrome bd-II oxidase subunit I YP_001729955.1 1090891 D 316385 CDS YP_001729956.1 170080636 6060155 1092447..1093583 1 NC_010473.1 contains synonymous changes in codon 277; cytochrome bd-II oxidase subunit II 1093583 appB 6060155 appB Escherichia coli str. K-12 substr. DH10B cytochrome bd-II oxidase subunit II YP_001729956.1 1092447 D 316385 CDS YP_001729957.1 170080637 6060145 1093768..1095066 1 NC_010473.1 phosphoanhydride phosphorylase 1095066 appA 6060145 appA Escherichia coli str. K-12 substr. DH10B phosphoanhydride phosphorylase YP_001729957.1 1093768 D 316385 CDS YP_001729958.1 170080638 6060149 complement(1095181..1097361) 1 NC_010473.1 cryptic autophosphorylating protein tyrosine kinase Etk 1097361 etk 6060149 etk Escherichia coli str. K-12 substr. DH10B cryptic autophosphorylating protein tyrosine kinase Etk YP_001729958.1 1095181 R 316385 CDS YP_001729959.1 170080639 6060138 complement(1097381..1097827) 1 NC_010473.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase 1097827 etp 6060138 etp Escherichia coli str. K-12 substr. DH10B phosphotyrosine-protein phosphatase YP_001729959.1 1097381 R 316385 CDS YP_001729960.1 170080640 6060104 complement(1097815..1098954) 1 NC_010473.1 exopolysaccharide export protein 1098954 gfcE 6060104 gfcE Escherichia coli str. K-12 substr. DH10B exopolysaccharide export protein YP_001729960.1 1097815 R 316385 CDS YP_001729961.1 170080641 6060113 complement(1099000..1101096) 1 NC_010473.1 hypothetical protein 1101096 gfcD 6060113 gfcD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729961.1 1099000 R 316385 CDS YP_001729962.1 170080642 6060054 complement(1101096..1101842) 1 NC_010473.1 hypothetical protein 1101842 gfcC 6060054 gfcC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729962.1 1101096 R 316385 CDS YP_001729963.1 170080643 6060125 complement(1101839..1102483) 1 NC_010473.1 outer membrane lipoprotein 1102483 gfcB 6060125 gfcB Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein YP_001729963.1 1101839 R 316385 CDS YP_001729964.1 170080644 6059948 complement(1102590..1102895) 1 NC_010473.1 hypothetical protein 1102895 gfcA 6059948 gfcA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729964.1 1102590 R 316385 CDS YP_001729965.1 170080645 6059974 1102984..1103259 1 NC_010473.1 IS1 repressor protein InsA 1103259 insA-4 6059974 insA-4 Escherichia coli str. K-12 substr. DH10B IS1 repressor protein InsA YP_001729965.1 1102984 D 316385 CDS YP_001729966.1 170080646 6059912 1103178..1103681 1 NC_010473.1 IS1 transposase InsAB' 1103681 insB-4 6059912 insB-4 Escherichia coli str. K-12 substr. DH10B IS1 transposase InsAB' YP_001729966.1 1103178 D 316385 CDS YP_001729967.1 170080647 6059997 complement(1104114..1104326) 1 NC_010473.1 CspA family stress protein 1104326 cspH 6059997 cspH Escherichia coli str. K-12 substr. DH10B CspA family stress protein YP_001729967.1 1104114 R 316385 CDS YP_001729968.1 170080648 6060151 1104612..1104824 1 NC_010473.1 cold shock protein CspG 1104824 cspG 6060151 cspG Escherichia coli str. K-12 substr. DH10B cold shock protein CspG YP_001729968.1 1104612 D 316385 CDS YP_001729969.1 170080649 6060144 1104998..1105228 1 NC_010473.1 cold shock gene 1105228 ymcE 6060144 ymcE Escherichia coli str. K-12 substr. DH10B cold shock gene YP_001729969.1 1104998 D 316385 CDS YP_001729970.1 170080650 6059896 1105218..1105391 1 NC_010473.1 regulator of phosphatidylethanolamine synthesis 1105391 gnsA 6059896 gnsA Escherichia coli str. K-12 substr. DH10B regulator of phosphatidylethanolamine synthesis YP_001729970.1 1105218 D 316385 CDS YP_001729971.1 170080651 6059908 complement(1105440..1106513) 1 NC_010473.1 4Fe-4S binding protein 1106513 yccM 6059908 yccM Escherichia coli str. K-12 substr. DH10B 4Fe-4S binding protein YP_001729971.1 1105440 R 316385 CDS YP_001729972.1 170080652 6059859 complement(1106585..1109329) 1 NC_010473.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1109329 torS 6059859 torS Escherichia coli str. K-12 substr. DH10B hybrid sensory histidine kinase TorS YP_001729972.1 1106585 R 316385 CDS YP_001729973.1 170080653 6059865 1109412..1110440 1 NC_010473.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1110440 torT 6059865 torT Escherichia coli str. K-12 substr. DH10B TMAO reductase system periplasmic protein TorT YP_001729973.1 1109412 D 316385 CDS YP_001729974.1 170080654 6059909 complement(1110413..1111105) 1 NC_010473.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1111105 torR 6059909 torR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator TorR YP_001729974.1 1110413 R 316385 CDS YP_001729975.1 170080655 6059809 1111235..1112407 1 NC_010473.1 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1112407 torC 6059809 torC Escherichia coli str. K-12 substr. DH10B trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit YP_001729975.1 1111235 D 316385 CDS YP_001729976.1 170080656 6059739 1112407..1114953 1 NC_010473.1 trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1114953 torA 6059739 torA Escherichia coli str. K-12 substr. DH10B trimethylamine N-oxide (TMAO) reductase I, catalytic subunit YP_001729976.1 1112407 D 316385 CDS YP_001729977.1 170080657 6059752 1114950..1115549 1 NC_010473.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1115549 torD 6059752 torD Escherichia coli str. K-12 substr. DH10B chaperone protein TorD YP_001729977.1 1114950 D 316385 CDS YP_001729978.1 170080658 6059720 complement(1115701..1116006) 1 NC_010473.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1116006 cbpM 6059720 cbpM Escherichia coli str. K-12 substr. DH10B chaperone-modulator protein CbpM YP_001729978.1 1115701 R 316385 CDS YP_001729979.1 170080659 6059667 complement(1116006..1116926) 1 NC_010473.1 DnaJ-like protein that functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1116926 cbpA 6059667 cbpA Escherichia coli str. K-12 substr. DH10B curved DNA-binding protein CbpA YP_001729979.1 1116006 R 316385 CDS YP_001729980.1 170080660 6059689 1117187..1118443 1 NC_010473.1 hypothetical protein 1118443 yccE 6059689 yccE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729980.1 1117187 D 316385 CDS YP_001729981.1 170080661 6059655 1118736..1119977 1 NC_010473.1 glucose-1-phosphatase/inositol phosphatase 1119977 agp 6059655 agp Escherichia coli str. K-12 substr. DH10B glucose-1-phosphatase/inositol phosphatase YP_001729981.1 1118736 D 316385 CDS YP_001729982.1 170080662 6059713 complement(1120015..1120242) 1 NC_010473.1 hypothetical protein 1120242 yccJ 6059713 yccJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729982.1 1120015 R 316385 CDS YP_001729983.1 170080663 6059642 complement(1120263..1120859) 1 NC_010473.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1120859 wrbA 6059642 wrbA Escherichia coli str. K-12 substr. DH10B TrpR binding protein WrbA YP_001729983.1 1120263 R 316385 CDS YP_001729984.1 170080664 6059645 1121232..1121405 1 NC_010473.1 hypothetical protein 1121405 ymdF 6059645 ymdF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729984.1 1121232 D 316385 CDS YP_001729985.1 170080665 6059615 complement(1121662..1122990) 1 NC_010473.1 pyrimidine transporter 1122990 rutG 6059615 rutG Escherichia coli str. K-12 substr. DH10B pyrimidine transporter YP_001729985.1 1121662 R 316385 CDS YP_001729986.1 170080666 6059652 complement(1123011..1123505) 1 NC_010473.1 oxidoreductase, flavin:NADH component 1123505 rutF 6059652 rutF Escherichia coli str. K-12 substr. DH10B oxidoreductase, flavin:NADH component YP_001729986.1 1123011 R 316385 CDS YP_001729987.1 170080667 6059777 complement(1123516..1124106) 1 NC_010473.1 hypothetical protein 1124106 rutE 6059777 rutE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729987.1 1123516 R 316385 CDS YP_001729988.1 170080668 6059721 complement(1124116..1124916) 1 NC_010473.1 hydrolase 1124916 rutD 6059721 rutD Escherichia coli str. K-12 substr. DH10B hydrolase YP_001729988.1 1124116 R 316385 CDS YP_001729989.1 170080669 6059549 complement(1124924..1125310) 1 NC_010473.1 hypothetical protein 1125310 rutC 6059549 rutC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729989.1 1124924 R 316385 CDS YP_001729990.1 170080670 6059552 complement(1125322..1126014) 1 NC_010473.1 isochorismatase 1126014 rutB 6059552 rutB Escherichia coli str. K-12 substr. DH10B isochorismatase YP_001729990.1 1125322 R 316385 CDS YP_001729991.1 170080671 6059490 complement(1126014..1127162) 1 NC_010473.1 monooxygenase 1127162 rutA 6059490 rutA Escherichia coli str. K-12 substr. DH10B monooxygenase YP_001729991.1 1126014 R 316385 CDS YP_001729992.1 170080672 6059538 1127393..1128031 1 NC_010473.1 rut operon repressor 1128031 rutR 6059538 rutR Escherichia coli str. K-12 substr. DH10B rut operon repressor YP_001729992.1 1127393 D 316385 CDS YP_001729993.1 170080673 6059557 complement(1128071..1132033) 1 NC_010473.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1132033 putA 6059557 putA Escherichia coli str. K-12 substr. DH10B trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_001729993.1 1128071 R 316385 CDS YP_001729994.1 170080674 6059483 1132456..1133964 1 NC_010473.1 proline:sodium symporter 1133964 putP 6059483 putP Escherichia coli str. K-12 substr. DH10B proline:sodium symporter YP_001729994.1 1132456 D 316385 CDS YP_001729995.1 170080675 6061324 1135394..1136521 1 NC_010473.1 hypothetical protein 1136521 efeO 6061324 efeO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729995.1 1135394 D 316385 CDS YP_001729996.1 170080676 6059455 1136527..1137798 1 NC_010473.1 redox component of a tripartite ferrous iron transporter 1137798 efeB 6059455 efeB Escherichia coli str. K-12 substr. DH10B redox component of a tripartite ferrous iron transporter YP_001729996.1 1136527 D 316385 CDS YP_001729997.1 170080677 6059431 1138143..1139207 1 NC_010473.1 hypothetical protein 1139207 phoH 6059431 phoH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001729997.1 1138143 D 316385 CDS YP_001729998.1 170080678 6059410 complement(1139257..1139670) 1 NC_010473.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; putative PGA biosynthesis protein 1139670 pgaD 6059410 pgaD Escherichia coli str. K-12 substr. DH10B putative PGA biosynthesis protein YP_001729998.1 1139257 R 316385 CDS YP_001729999.1 170080679 6059425 complement(1139672..1140997) 1 NC_010473.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1140997 pgaC 6059425 pgaC Escherichia coli str. K-12 substr. DH10B N-glycosyltransferase YP_001729999.1 1139672 R 316385 CDS YP_001730000.1 170080680 6059405 complement(1140990..1143008) 1 NC_010473.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1143008 pgaB 6059405 pgaB Escherichia coli str. K-12 substr. DH10B outer membrane N-deacetylase YP_001730000.1 1140990 R 316385 CDS YP_001730001.1 170080681 6059428 complement(1143017..1145440) 1 NC_010473.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1145440 pgaA 6059428 pgaA Escherichia coli str. K-12 substr. DH10B outer membrane protein PgaA YP_001730001.1 1143017 R 316385 CDS YP_001730002.1 170080682 6062272 complement(1148762..1149628) 1 NC_010473.1 IS3 element protein InsF 1149628 insF-4 6062272 insF-4 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsF YP_001730002.1 1148762 R 316385 CDS YP_001730003.1 170080683 6059377 complement(1149625..1149933) 1 NC_010473.1 IS3 element protein InsE 1149933 insE-4 6059377 insE-4 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsE YP_001730003.1 1149625 R 316385 CDS YP_001730004.1 170080684 6059062 1150330..1151316 1 NC_010473.1 inner membrane protein 1151316 ycdU 6059062 ycdU Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730004.1 1150330 D 316385 CDS YP_001730005.1 170080685 6060511 1152554..1153492 1 NC_010473.1 2-ketoacid reductase 1153492 ycdW 6060511 ycdW Escherichia coli str. K-12 substr. DH10B 2-ketoacid reductase YP_001730005.1 1152554 D 316385 CDS YP_001730006.1 170080686 6059470 1153547..1154284 1 NC_010473.1 putative hydrolase 1154284 ycdX 6059470 ycdX Escherichia coli str. K-12 substr. DH10B putative hydrolase YP_001730006.1 1153547 D 316385 CDS YP_001730007.1 170080687 6059439 1154308..1154862 1 NC_010473.1 contains the nonsynonymous change C144Y; hypothetical protein 1154862 ycdY 6059439 ycdY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730007.1 1154308 D 316385 CDS YP_001730008.1 170080688 6059338 1154964..1155455 1 NC_010473.1 inner membrane protein 1155455 ycdZ 6059338 ycdZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730008.1 1154964 D 316385 CDS YP_001730009.1 170080689 6059346 complement(1155519..1156352) 1 NC_010473.1 outer membrane channel lipoprotein 1156352 csgG 6059346 csgG Escherichia coli str. K-12 substr. DH10B outer membrane channel lipoprotein YP_001730009.1 1155519 R 316385 CDS YP_001730010.1 170080690 6059299 complement(1156379..1156795) 1 NC_010473.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1156795 csgF 6059299 csgF Escherichia coli str. K-12 substr. DH10B curli assembly protein CsgF YP_001730010.1 1156379 R 316385 CDS YP_001730011.1 170080691 6059336 complement(1156820..1157209) 1 NC_010473.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1157209 csgE 6059336 csgE Escherichia coli str. K-12 substr. DH10B curli assembly protein CsgE YP_001730011.1 1156820 R 316385 CDS YP_001730012.1 170080692 6059357 complement(1157214..1157864) 1 NC_010473.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1157864 csgD 6059357 csgD Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator CsgD YP_001730012.1 1157214 R 316385 CDS YP_001730013.1 170080693 6059298 1158619..1159074 1 NC_010473.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1159074 csgB 6059298 csgB Escherichia coli str. K-12 substr. DH10B curlin minor subunit YP_001730013.1 1158619 D 316385 CDS YP_001730014.1 170080694 6059265 1159115..1159570 1 NC_010473.1 cryptic curlin major subunit 1159570 csgA 6059265 csgA Escherichia coli str. K-12 substr. DH10B cryptic curlin major subunit YP_001730014.1 1159115 D 316385 CDS YP_001730015.1 170080695 6059266 1159629..1159961 1 NC_010473.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein 1159961 csgC 6059266 csgC Escherichia coli str. K-12 substr. DH10B putative autoagglutination protein YP_001730015.1 1159629 D 316385 CDS YP_001730016.1 170080696 6059241 1160082..1160393 1 NC_010473.1 hypothetical protein 1160393 ymdA 6059241 ymdA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730016.1 1160082 D 316385 CDS YP_001730017.1 170080697 6059212 1160488..1161021 1 NC_010473.1 hypothetical protein 1161021 ymdB 6059212 ymdB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730017.1 1160488 D 316385 CDS YP_001730018.1 170080698 6059214 1161023..1162444 1 NC_010473.1 hydrolase 1162444 ymdC 6059214 ymdC Escherichia coli str. K-12 substr. DH10B hydrolase YP_001730018.1 1161023 D 316385 CDS YP_001730019.1 170080699 6059204 complement(1162452..1163609) 1 NC_010473.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1163609 mdoC 6059204 mdoC Escherichia coli str. K-12 substr. DH10B glucans biosynthesis protein YP_001730019.1 1162452 R 316385 CDS YP_001730020.1 170080700 6059215 1164003..1165538 1 NC_010473.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1165538 mdoG 6059215 mdoG Escherichia coli str. K-12 substr. DH10B glucan biosynthesis protein G YP_001730020.1 1164003 D 316385 CDS YP_001730021.1 170080701 6059174 1165531..1168074 1 NC_010473.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1168074 mdoH 6059174 mdoH Escherichia coli str. K-12 substr. DH10B glucosyltransferase MdoH YP_001730021.1 1165531 D 316385 CDS YP_001730022.1 170080702 6059188 1168247..1168474 1 NC_010473.1 hypothetical protein 1168474 yceK 6059188 yceK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730022.1 1168247 D 316385 CDS YP_001730023.1 170080703 6059171 complement(1168475..1168849) 1 NC_010473.1 hypothetical protein 1168849 msyB 6059171 msyB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730023.1 1168475 R 316385 CDS YP_001730024.1 170080704 6059189 complement(1168932..1170158) 1 NC_010473.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1170158 mdtG 6059189 mdtG Escherichia coli str. K-12 substr. DH10B drug efflux system protein MdtG YP_001730024.1 1168932 R 316385 CDS YP_001730025.1 170080705 6059293 complement(1170330..1171250) 1 NC_010473.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1171250 lpxL 6059293 lpxL Escherichia coli str. K-12 substr. DH10B lipid A biosynthesis lauroyl acyltransferase YP_001730025.1 1170330 R 316385 CDS YP_001730026.1 170080706 6059244 1171475..1172527 1 NC_010473.1 hypothetical protein 1172527 yceA 6059244 yceA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730026.1 1171475 D 316385 CDS YP_001730027.1 170080707 6059386 complement(1172569..1173144) 1 NC_010473.1 hypothetical protein 1173144 yceI 6059386 yceI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730027.1 1172569 R 316385 CDS YP_001730028.1 170080708 6059115 complement(1173148..1173714) 1 NC_010473.1 cytochrome b561 1173714 yceJ 6059115 yceJ Escherichia coli str. K-12 substr. DH10B cytochrome b561 YP_001730028.1 1173148 R 316385 CDS YP_001730029.1 170080709 6059145 complement(1173975..1174115) 1 NC_010473.1 hypothetical protein 1174115 yceO 6059145 yceO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730029.1 1173975 R 316385 CDS YP_001730030.1 170080710 6059108 complement(1174136..1175254) 1 NC_010473.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1175254 solA 6059108 solA Escherichia coli str. K-12 substr. DH10B N-methyltryptophan oxidase YP_001730030.1 1174136 R 316385 CDS YP_001730031.1 170080711 6059109 complement(1175369..1175623) 1 NC_010473.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1175623 bssS 6059109 bssS Escherichia coli str. K-12 substr. DH10B biofilm formation regulatory protein BssS YP_001730031.1 1175369 R 316385 CDS YP_001730032.1 170080712 6059150 complement(1175910..1176155) 1 NC_010473.1 DNA damage-inducible protein I 1176155 dinI 6059150 dinI Escherichia coli str. K-12 substr. DH10B DNA damage-inducible protein I YP_001730032.1 1175910 R 316385 CDS YP_001730033.1 170080713 6059070 complement(1176229..1177275) 1 NC_010473.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1177275 pyrC 6059070 pyrC Escherichia coli str. K-12 substr. DH10B dihydroorotase YP_001730033.1 1176229 R 316385 CDS YP_001730034.1 170080714 6059047 complement(1177381..1177941) 1 NC_010473.1 hypothetical protein 1177941 yceB 6059047 yceB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730034.1 1177381 R 316385 CDS YP_001730035.1 170080715 6059059 complement(1178075..1178722) 1 NC_010473.1 cofactor involved in the reduction of disulfides; glutaredoxin 1178722 grxB 6059059 grxB Escherichia coli str. K-12 substr. DH10B glutaredoxin YP_001730035.1 1178075 R 316385 CDS YP_001730036.1 170080716 6059039 complement(1178786..1179994) 1 NC_010473.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1179994 mdtH 6059039 mdtH Escherichia coli str. K-12 substr. DH10B multidrug resistance protein MdtH YP_001730036.1 1178786 R 316385 CDS YP_001730037.1 170080717 6059016 1180230..1180814 1 NC_010473.1 ribosomal-protein-S5-alanine N-acetyltransferase 1180814 rimJ 6059016 rimJ Escherichia coli str. K-12 substr. DH10B ribosomal-protein-S5-alanine N-acetyltransferase YP_001730037.1 1180230 D 316385 CDS YP_001730038.1 170080718 6059031 1180825..1181472 1 NC_010473.1 hypothetical protein 1181472 yceH 6059031 yceH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730038.1 1180825 D 316385 CDS YP_001730039.1 170080719 6059010 1181474..1182397 1 NC_010473.1 oxidoreductase 1182397 mviM 6059010 mviM Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001730039.1 1181474 D 316385 CDS YP_001730040.1 170080720 6059037 1182507..1184042 1 NC_010473.1 inner membrane protein 1184042 yceN 6059037 yceN Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730040.1 1182507 D 316385 CDS YP_001730041.1 170080721 6059005 complement(1184082..1184498) 1 NC_010473.1 export chaperone for FlgK and FlgL 1184498 flgN 6059005 flgN Escherichia coli str. K-12 substr. DH10B export chaperone for FlgK and FlgL YP_001730041.1 1184082 R 316385 CDS YP_001730042.1 170080722 6059007 complement(1184503..1184796) 1 NC_010473.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1184796 flgM 6059007 flgM Escherichia coli str. K-12 substr. DH10B anti-sigma-28 factor FlgM YP_001730042.1 1184503 R 316385 CDS YP_001730043.1 170080723 6058997 complement(1184872..1185531) 1 NC_010473.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1185531 flgA 6058997 flgA Escherichia coli str. K-12 substr. DH10B flagellar basal body P-ring biosynthesis protein FlgA YP_001730043.1 1184872 R 316385 CDS YP_001730044.1 170080724 6059008 1185686..1186102 1 NC_010473.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1186102 flgB 6059008 flgB Escherichia coli str. K-12 substr. DH10B flagellar basal body rod protein FlgB YP_001730044.1 1185686 D 316385 CDS YP_001730045.1 170080725 6059068 1186106..1186510 1 NC_010473.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1186510 flgC 6059068 flgC Escherichia coli str. K-12 substr. DH10B flagellar basal body rod protein FlgC YP_001730045.1 1186106 D 316385 CDS YP_001730046.1 170080726 6059040 1186522..1187217 1 NC_010473.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1187217 flgD 6059040 flgD Escherichia coli str. K-12 substr. DH10B flagellar basal body rod modification protein YP_001730046.1 1186522 D 316385 CDS YP_001730047.1 170080727 6058938 1187242..1188450 1 NC_010473.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1188450 flgE 6058938 flgE Escherichia coli str. K-12 substr. DH10B flagellar hook protein FlgE YP_001730047.1 1187242 D 316385 CDS YP_001730048.1 170080728 6058953 1188470..1189225 1 NC_010473.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1189225 flgF 6058953 flgF Escherichia coli str. K-12 substr. DH10B flagellar basal body rod protein FlgF YP_001730048.1 1188470 D 316385 CDS YP_001730049.1 170080729 6058919 1189397..1190179 1 NC_010473.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1190179 flgG 6058919 flgG Escherichia coli str. K-12 substr. DH10B flagellar basal body rod protein FlgG YP_001730049.1 1189397 D 316385 CDS YP_001730050.1 170080730 6058922 1190232..1190930 1 NC_010473.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1190930 flgH 6058922 flgH Escherichia coli str. K-12 substr. DH10B flagellar basal body L-ring protein YP_001730050.1 1190232 D 316385 CDS YP_001730051.1 170080731 6058977 1190942..1192039 1 NC_010473.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1192039 flgI 6058977 flgI Escherichia coli str. K-12 substr. DH10B flagellar basal body P-ring protein YP_001730051.1 1190942 D 316385 CDS YP_001730052.1 170080732 6058914 1192039..1192980 1 NC_010473.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1192980 flgJ 6058914 flgJ Escherichia coli str. K-12 substr. DH10B flagellar rod assembly protein/muramidase FlgJ YP_001730052.1 1192039 D 316385 CDS YP_001730053.1 170080733 6058889 1193046..1194689 1 NC_010473.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1194689 flgK 6058889 flgK Escherichia coli str. K-12 substr. DH10B flagellar hook-associated protein FlgK YP_001730053.1 1193046 D 316385 CDS YP_001730054.1 170080734 6058891 1194701..1195654 1 NC_010473.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1195654 flgL 6058891 flgL Escherichia coli str. K-12 substr. DH10B flagellar hook-associated protein FlgL YP_001730054.1 1194701 D 316385 CDS YP_001730055.1 170080735 6058874 complement(1195850..1199035) 1 NC_010473.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1199035 rne 6058874 rne Escherichia coli str. K-12 substr. DH10B ribonuclease E YP_001730055.1 1195850 R 316385 CDS YP_001730056.1 170080736 6058842 1199170..1199490 1 NC_010473.1 hypothetical protein 1199490 yceQ 6058842 yceQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730056.1 1199170 D 316385 CDS YP_001730057.1 170080737 6058855 1199608..1200567 1 NC_010473.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1200567 rluC 6058855 rluC Escherichia coli str. K-12 substr. DH10B 23S rRNA pseudouridylate synthase C YP_001730057.1 1199608 D 316385 CDS YP_001730058.1 170080738 6058836 complement(1200679..1201263) 1 NC_010473.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1201263 yceF 6058836 yceF Escherichia coli str. K-12 substr. DH10B Maf-like protein YP_001730058.1 1200679 R 316385 CDS YP_001730059.1 170080739 6061961 1201462..1201983 1 NC_010473.1 hypothetical protein 1201983 yceD 6061961 yceD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730059.1 1201462 D 316385 CDS YP_001730060.1 170080740 6058827 1202035..1202208 1 NC_010473.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1202208 rpmF 6058827 rpmF Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L32 YP_001730060.1 1202035 D 316385 CDS YP_001730061.1 170080741 6058828 1202289..1203359 1 NC_010473.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1203359 plsX 6058828 plsX Escherichia coli str. K-12 substr. DH10B putative glycerol-3-phosphate acyltransferase PlsX YP_001730061.1 1202289 D 316385 CDS YP_001730062.1 170080742 6058821 1203427..1204380 1 NC_010473.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1204380 fabH 6058821 fabH Escherichia coli str. K-12 substr. DH10B 3-oxoacyl-ACP synthase YP_001730062.1 1203427 D 316385 CDS YP_001730063.1 170080743 6058831 1204396..1205325 1 NC_010473.1 malonyl-CoA-[acyl-carrier-protein] transacylase 1205325 fabD 6058831 fabD Escherichia coli str. K-12 substr. DH10B malonyl-CoA-[acyl-carrier-protein] transacylase YP_001730063.1 1204396 D 316385 CDS YP_001730064.1 170080744 6058893 1205338..1206072 1 NC_010473.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1206072 fabG 6058893 fabG Escherichia coli str. K-12 substr. DH10B 3-ketoacyl-ACP reductase YP_001730064.1 1205338 D 316385 CDS YP_001730065.1 170080745 6058875 1206283..1206519 1 NC_010473.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1206519 acpP 6058875 acpP Escherichia coli str. K-12 substr. DH10B acyl carrier protein YP_001730065.1 1206283 D 316385 CDS YP_001730066.1 170080746 6058791 1206607..1207848 1 NC_010473.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1207848 fabF 6058791 fabF Escherichia coli str. K-12 substr. DH10B 3-oxoacyl-(acyl carrier protein) synthase II YP_001730066.1 1206607 D 316385 CDS YP_001730067.1 170080747 6058792 1207968..1208777 1 NC_010473.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1208777 pabC 6058792 pabC Escherichia coli str. K-12 substr. DH10B 4-amino-4-deoxychorismate lyase YP_001730067.1 1207968 D 316385 CDS YP_001730068.1 170080748 6058777 1208780..1209802 1 NC_010473.1 hypothetical protein 1209802 yceG 6058777 yceG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730068.1 1208780 D 316385 CDS YP_001730069.1 170080749 6058785 1209792..1210433 1 NC_010473.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1210433 tmk 6058785 tmk Escherichia coli str. K-12 substr. DH10B thymidylate kinase YP_001730069.1 1209792 D 316385 CDS YP_001730070.1 170080750 6058796 1210430..1211434 1 NC_010473.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1211434 holB 6058796 holB Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit delta' YP_001730070.1 1210430 D 316385 CDS YP_001730071.1 170080751 6058760 1211445..1212242 1 NC_010473.1 putative metallodependent hydrolase 1212242 ycfH 6058760 ycfH Escherichia coli str. K-12 substr. DH10B putative metallodependent hydrolase YP_001730071.1 1211445 D 316385 CDS YP_001730072.1 170080752 6058738 1212537..1213970 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1213970 ptsG 6058738 ptsG Escherichia coli str. K-12 substr. DH10B PTS system glucose-specific transporter subunit IIBC YP_001730072.1 1212537 D 316385 CDS YP_001730073.1 170080753 6058740 complement(1214030..1216219) 1 NC_010473.1 ferric-rhodotorulic acid outer membrane transporter 1216219 fhuE 6058740 fhuE Escherichia coli str. K-12 substr. DH10B ferric-rhodotorulic acid outer membrane transporter YP_001730073.1 1214030 R 316385 CDS YP_001730074.1 170080754 6058735 1216553..1216912 1 NC_010473.1 purine nucleoside phosphoramidase 1216912 hinT 6058735 hinT Escherichia coli str. K-12 substr. DH10B purine nucleoside phosphoramidase YP_001730074.1 1216553 D 316385 CDS YP_001730075.1 170080755 6058711 1216915..1217292 1 NC_010473.1 lipoprotein 1217292 ycfL 6058711 ycfL Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730075.1 1216915 D 316385 CDS YP_001730076.1 170080756 6058731 1217306..1217947 1 NC_010473.1 outer membrane lipoprotein 1217947 ycfM 6058731 ycfM Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein YP_001730076.1 1217306 D 316385 CDS YP_001730077.1 170080757 6058697 1217928..1218752 1 NC_010473.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1218752 thiK 6058697 thiK Escherichia coli str. K-12 substr. DH10B thiamine kinase YP_001730077.1 1217928 D 316385 CDS YP_001730078.1 170080758 6058733 1218763..1219788 1 NC_010473.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1219788 nagZ 6058733 nagZ Escherichia coli str. K-12 substr. DH10B beta-hexosaminidase YP_001730078.1 1218763 D 316385 CDS YP_001730079.1 170080759 6058670 1219811..1220353 1 NC_010473.1 hypothetical protein 1220353 ycfP 6058670 ycfP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730079.1 1219811 D 316385 CDS YP_001730080.1 170080760 6058686 1220753..1222057 1 NC_010473.1 respiratory NADH dehydrogenase 2/cupric reductase 1222057 ndh 6058686 ndh Escherichia coli str. K-12 substr. DH10B respiratory NADH dehydrogenase 2/cupric reductase YP_001730080.1 1220753 D 316385 CDS YP_001730081.1 170080761 6058668 1222267..1222806 1 NC_010473.1 hypothetical protein 1222806 ycfJ 6058668 ycfJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730081.1 1222267 D 316385 CDS YP_001730082.1 170080762 6058691 complement(1222868..1223500) 1 NC_010473.1 DNA-binding transcriptional regulator 1223500 ycfQ 6058691 ycfQ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730082.1 1222868 R 316385 CDS YP_001730083.1 170080763 6060652 1223741..1223998 1 NC_010473.1 hypothetical protein 1223998 ycfR 6060652 ycfR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730083.1 1223741 D 316385 CDS YP_001730084.1 170080764 6058759 complement(1224080..1225042) 1 NC_010473.1 contains the nonsynonymous change L180P; hypothetical protein 1225042 ycfS 6058759 ycfS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730084.1 1224080 R 316385 CDS YP_001730085.1 170080765 6058736 complement(1225186..1228632) 1 NC_010473.1 transcription-repair coupling factor 1228632 mfd 6058736 mfd Escherichia coli str. K-12 substr. DH10B transcription-repair coupling factor YP_001730085.1 1225186 R 316385 CDS YP_001730086.1 170080766 6058642 complement(1228760..1229833) 1 NC_010473.1 inner membrane protein 1229833 ycfT 6058642 ycfT Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730086.1 1228760 R 316385 CDS YP_001730087.1 170080767 6058652 1230095..1231294 1 NC_010473.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1231294 lolC 6058652 lolC Escherichia coli str. K-12 substr. DH10B outer membrane-specific lipoprotein transporter subunit LolC YP_001730087.1 1230095 D 316385 CDS YP_001730088.1 170080768 6058630 1231287..1231988 1 NC_010473.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1231988 lolD 6058630 lolD Escherichia coli str. K-12 substr. DH10B lipoprotein transporter ATP-binding subunit YP_001730088.1 1231287 D 316385 CDS YP_001730089.1 170080769 6058638 1231988..1233232 1 NC_010473.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1233232 lolE 6058638 lolE Escherichia coli str. K-12 substr. DH10B outer membrane-specific lipoprotein transporter subunit LolE YP_001730089.1 1231988 D 316385 CDS YP_001730090.1 170080770 6058658 1233261..1234172 1 NC_010473.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1234172 nagK 6058658 nagK Escherichia coli str. K-12 substr. DH10B N-acetyl-D-glucosamine kinase YP_001730090.1 1233261 D 316385 CDS YP_001730091.1 170080771 6058617 1234188..1235027 1 NC_010473.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1235027 cobB 6058617 cobB Escherichia coli str. K-12 substr. DH10B NAD-dependent deacetylase YP_001730091.1 1234188 D 316385 CDS YP_001730092.1 170080772 6058619 complement(1235147..1235935) 1 NC_010473.1 inner membrane protein 1235935 ycfZ 6058619 ycfZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730092.1 1235147 R 316385 CDS YP_001730093.1 170080773 6058610 complement(1235932..1236393) 1 NC_010473.1 inner membrane protein 1236393 ymfA 6058610 ymfA Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730093.1 1235932 R 316385 CDS YP_001730094.1 170080774 6058612 complement(1236451..1237497) 1 NC_010473.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1237497 potD 6058612 potD Escherichia coli str. K-12 substr. DH10B spermidine/putrescine ABC transporter substrate-binding protein YP_001730094.1 1236451 R 316385 CDS YP_001730095.1 170080775 6058624 complement(1237494..1238288) 1 NC_010473.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1238288 potC 6058624 potC Escherichia coli str. K-12 substr. DH10B spermidine/putrescine ABC transporter membrane protein YP_001730095.1 1237494 R 316385 CDS YP_001730096.1 170080776 6058608 complement(1238285..1239112) 1 NC_010473.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1239112 potB 6058608 potB Escherichia coli str. K-12 substr. DH10B spermidine/putrescine ABC transporter membrane protein YP_001730096.1 1238285 R 316385 CDS YP_001730097.1 170080777 6058606 complement(1239126..1240262) 1 NC_010473.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1240262 potA 6058606 potA Escherichia coli str. K-12 substr. DH10B putrescine/spermidine ABC transporter ATPase YP_001730097.1 1239126 R 316385 CDS YP_001730098.1 170080778 6058603 1240512..1241738 1 NC_010473.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1241738 pepT 6058603 pepT Escherichia coli str. K-12 substr. DH10B peptidase T YP_001730098.1 1240512 D 316385 CDS YP_001730099.1 170080779 6058604 complement(1241787..1242908) 1 NC_010473.1 hypothetical protein 1242908 ycfD 6058604 ycfD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730099.1 1241787 R 316385 CDS YP_001730100.1 170080780 6058588 complement(1242984..1244444) 1 NC_010473.1 sensor protein PhoQ 1244444 phoQ 6058588 phoQ Escherichia coli str. K-12 substr. DH10B sensor protein PhoQ YP_001730100.1 1242984 R 316385 CDS YP_001730101.1 170080781 6058593 complement(1244444..1245115) 1 NC_010473.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1245115 phoP 6058593 phoP Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator PhoP YP_001730101.1 1244444 R 316385 CDS YP_001730102.1 170080782 6058585 complement(1245284..1246654) 1 NC_010473.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1246654 purB 6058585 purB Escherichia coli str. K-12 substr. DH10B adenylosuccinate lyase YP_001730102.1 1245284 R 316385 CDS YP_001730103.1 170080783 6058581 complement(1246658..1247299) 1 NC_010473.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1247299 hflD 6058581 hflD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730103.1 1246658 R 316385 CDS YP_001730104.1 170080784 6058582 complement(1247335..1248441) 1 NC_010473.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1248441 mnmA 6058582 mnmA Escherichia coli str. K-12 substr. DH10B tRNA-specific 2-thiouridylase MnmA YP_001730104.1 1247335 R 316385 CDS YP_001730105.1 170080785 6058579 complement(1248495..1248956) 1 NC_010473.1 bifunctional thiamin pyrimidine pyrophosphate hydrolase and thiamin pyrophosphate hydrolase 1248956 nudJ 6058579 nudJ Escherichia coli str. K-12 substr. DH10B bifunctional thiamin pyrimidine pyrophosphate hydrolase and thiamin pyrophosphate hydrolase YP_001730105.1 1248495 R 316385 CDS YP_001730106.1 170080786 6058584 complement(1248966..1249619) 1 NC_010473.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1249619 rluE 6058584 rluE Escherichia coli str. K-12 substr. DH10B 23S rRNA pseudouridine synthase E YP_001730106.1 1248966 R 316385 CDS YP_001730107.1 170080787 6058576 1249791..1251041 1 NC_010473.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1251041 icd 6058576 icd Escherichia coli str. K-12 substr. DH10B isocitrate dehydrogenase YP_001730107.1 1249791 D 316385 CDS YP_001730108.1 170080788 6058577 complement(1251144..1251467) 1 NC_010473.1 hypothetical protein 1251467 elbA 6058577 elbA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730108.1 1251144 R 316385 CDS YP_001730109.1 170080789 6058575 complement(1252167..1252571) 1 NC_010473.1 hypothetical protein 1252571 ycgX 6058575 ycgX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730109.1 1252167 R 316385 CDS YP_001730110.1 170080790 6058578 complement(1252792..1253523) 1 NC_010473.1 DNA-binding transcriptional regulator 1253523 ycgE 6058578 ycgE Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730110.1 1252792 R 316385 CDS YP_001730111.1 170080791 6058571 complement(1253728..1254939) 1 NC_010473.1 FAD-binding phosphodiesterase 1254939 ycgF 6058571 ycgF Escherichia coli str. K-12 substr. DH10B FAD-binding phosphodiesterase YP_001730111.1 1253728 R 316385 CDS YP_001730112.1 170080792 6058572 1255253..1255489 1 NC_010473.1 hypothetical protein 1255489 ycgZ 6058572 ycgZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730112.1 1255253 D 316385 CDS YP_001730113.1 170080793 6058568 1255532..1255804 1 NC_010473.1 hypothetical protein 1255804 ymgA 6058568 ymgA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730113.1 1255532 D 316385 CDS YP_001730114.1 170080794 6058573 1255833..1256099 1 NC_010473.1 hypothetical protein 1256099 ymgB 6058573 ymgB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730114.1 1255833 D 316385 CDS YP_001730115.1 170080795 6058605 1256212..1256460 1 NC_010473.1 hypothetical protein 1256460 ymgC 6058605 ymgC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730115.1 1256212 D 316385 CDS YP_001730116.1 170080796 6058598 1256792..1258315 1 NC_010473.1 inner membrane protein 1258315 ycgG 6058598 ycgG Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730116.1 1256792 D 316385 CDS YP_001730117.1 170080797 6060417 1258447..1258665 1 NC_010473.1 hypothetical protein 1258665 ymgF 6060417 ymgF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730117.1 1258447 D 316385 CDS YP_001730118.1 170080798 6062256 complement(1261769..1262098) 1 NC_010473.1 hypothetical protein 1262098 ymgD 6062256 ymgD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730118.1 1261769 R 316385 CDS YP_001730119.1 170080799 6060459 complement(1262108..1262383) 1 NC_010473.1 hypothetical protein 1262383 ymgG 6060459 ymgG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730119.1 1262108 R 316385 CDS YP_001730120.1 170080800 6060447 complement(1262454..1262627) 1 NC_010473.1 hypothetical protein 1262627 ymgI 6060447 ymgI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730120.1 1262454 R 316385 CDS YP_001730121.1 170080801 6060446 1262728..1262913 1 NC_010473.1 hypothetical protein 1262913 ymgJ 6060446 ymgJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730121.1 1262728 D 316385 CDS YP_001730122.1 170080802 6061217 complement(1263743..1264009) 1 NC_010473.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1264009 minE 6061217 minE Escherichia coli str. K-12 substr. DH10B cell division topological specificity factor MinE YP_001730122.1 1263743 R 316385 CDS YP_001730123.1 170080803 6060438 complement(1264013..1264825) 1 NC_010473.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1264825 minD 6060438 minD Escherichia coli str. K-12 substr. DH10B cell division inhibitor MinD YP_001730123.1 1264013 R 316385 CDS YP_001730124.1 170080804 6060428 complement(1264849..1265544) 1 NC_010473.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1265544 minC 6060428 minC Escherichia coli str. K-12 substr. DH10B septum formation inhibitor YP_001730124.1 1264849 R 316385 CDS YP_001730125.1 170080805 6058594 1266064..1266432 1 NC_010473.1 hypothetical protein 1266432 ycgJ 6058594 ycgJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730125.1 1266064 D 316385 CDS YP_001730126.1 170080806 6058586 complement(1266535..1266936) 1 NC_010473.1 hypothetical protein 1266936 ycgK 6058586 ycgK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730126.1 1266535 R 316385 CDS YP_001730127.1 170080807 6058562 1267145..1267471 1 NC_010473.1 hypothetical protein 1267471 ycgL 6058562 ycgL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730127.1 1267145 D 316385 CDS YP_001730128.1 170080808 6058564 1267543..1268202 1 NC_010473.1 hypothetical protein 1268202 ycgM 6058564 ycgM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730128.1 1267543 D 316385 CDS YP_001730129.1 170080809 6058557 1268279..1268740 1 NC_010473.1 hypothetical protein 1268740 ycgN 6058557 ycgN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730129.1 1268279 D 316385 CDS YP_001730130.1 170080810 6058558 complement(1268947..1269858) 1 NC_010473.1 Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E 1269858 hlyE 6058558 hlyE Escherichia coli str. K-12 substr. DH10B hemolysin E YP_001730130.1 1268947 R 316385 CDS YP_001730131.1 170080811 6058566 1270231..1270650 1 NC_010473.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1270650 umuD 6058566 umuD Escherichia coli str. K-12 substr. DH10B DNA polymerase V subunit UmuD YP_001730131.1 1270231 D 316385 CDS YP_001730132.1 170080812 6058556 1270650..1271918 1 NC_010473.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1271918 umuC 6058556 umuC Escherichia coli str. K-12 substr. DH10B DNA polymerase V subunit UmuC YP_001730132.1 1270650 D 316385 CDS YP_001730133.1 170080813 6058550 complement(1271964..1272494) 1 NC_010473.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1272494 dsbB 6058550 dsbB Escherichia coli str. K-12 substr. DH10B disulfide bond formation protein B YP_001730133.1 1271964 R 316385 CDS YP_001730134.1 170080814 6058552 complement(1272640..1274181) 1 NC_010473.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1274181 nhaB 6058552 nhaB Escherichia coli str. K-12 substr. DH10B sodium/proton antiporter YP_001730134.1 1272640 R 316385 CDS YP_001730135.1 170080815 6058547 1274402..1275121 1 NC_010473.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1275121 fadR 6058547 fadR Escherichia coli str. K-12 substr. DH10B fatty acid metabolism regulator YP_001730135.1 1274402 D 316385 CDS YP_001730136.1 170080816 6058539 complement(1275173..1276705) 1 NC_010473.1 SpoVR family protein 1276705 ycgB 6058539 ycgB Escherichia coli str. K-12 substr. DH10B SpoVR family protein YP_001730136.1 1275173 R 316385 CDS YP_001730137.1 170080817 6058541 1277035..1278333 1 NC_010473.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1278333 dadA 6058541 dadA Escherichia coli str. K-12 substr. DH10B D-amino acid dehydrogenase small subunit YP_001730137.1 1277035 D 316385 CDS YP_001730138.1 170080818 6058538 1278343..1279413 1 NC_010473.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1279413 dadX 6058538 dadX Escherichia coli str. K-12 substr. DH10B alanine racemase YP_001730138.1 1278343 D 316385 CDS YP_001730139.1 170080819 6058546 complement(1279799..1281535) 1 NC_010473.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1281535 cvrA 6058546 cvrA Escherichia coli str. K-12 substr. DH10B potassium/proton antiporter YP_001730139.1 1279799 R 316385 CDS YP_001730140.1 170080820 6058524 complement(1281630..1282544) 1 NC_010473.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1282544 ldcA 6058524 ldcA Escherichia coli str. K-12 substr. DH10B L,D-carboxypeptidase A YP_001730140.1 1281630 R 316385 CDS YP_001730141.1 170080821 6058529 1282644..1283255 1 NC_010473.1 lytic murein endotransglycosylase E 1283255 emtA 6058529 emtA Escherichia coli str. K-12 substr. DH10B lytic murein endotransglycosylase E YP_001730141.1 1282644 D 316385 CDS YP_001730142.1 170080822 6058521 complement(1283257..1283991) 1 NC_010473.1 protein involved in flagellar function; hypothetical protein 1283991 ycgR 6058521 ycgR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730142.1 1283257 R 316385 CDS YP_001730143.1 170080823 6058530 1284192..1284446 1 NC_010473.1 inner membrane protein 1284446 ymgE 6058530 ymgE Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730143.1 1284192 D 316385 CDS YP_001730144.1 170080824 6058553 1284624..1285064 1 NC_010473.1 hypothetical protein 1285064 ycgY 6058553 ycgY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730144.1 1284624 D 316385 CDS YP_001730145.1 170080825 6058548 complement(1285143..1286840) 1 NC_010473.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1286840 treA 6058548 treA Escherichia coli str. K-12 substr. DH10B trehalase YP_001730145.1 1285143 R 316385 CDS YP_001730146.1 170080826 6058512 complement(1287160..1288578) 1 NC_010473.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM 1288578 dhaM 6058512 dhaM Escherichia coli str. K-12 substr. DH10B dihydroxyacetone kinase subunit DhaM YP_001730146.1 1287160 R 316385 CDS YP_001730147.1 170080827 6058517 complement(1288589..1289221) 1 NC_010473.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 1289221 dhaL 6058517 dhaL Escherichia coli str. K-12 substr. DH10B dihydroxyacetone kinase subunit DhaL YP_001730147.1 1288589 R 316385 CDS YP_001730148.1 170080828 6058509 complement(1289232..1290302) 1 NC_010473.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1290302 dhaK 6058509 dhaK Escherichia coli str. K-12 substr. DH10B dihydroxyacetone kinase subunit DhaK YP_001730148.1 1289232 R 316385 CDS YP_001730149.1 170080829 6058511 1290530..1292449 1 NC_010473.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1292449 dhaR 6058511 dhaR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator DhaR YP_001730149.1 1290530 D 316385 CDS YP_001730150.1 170080830 6058518 complement(1292549..1295416) 1 NC_010473.1 adhesin 1295416 ycgV 6058518 ycgV Escherichia coli str. K-12 substr. DH10B adhesin YP_001730150.1 1292549 R 316385 CDS YP_001730151.1 170080831 6058508 complement(1296185..1297276) 1 NC_010473.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1297276 ychF 6058508 ychF Escherichia coli str. K-12 substr. DH10B GTP-dependent nucleic acid-binding protein EngD YP_001730151.1 1296185 R 316385 CDS YP_001730152.1 170080832 6058498 complement(1297393..1297977) 1 NC_010473.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1297977 pth 6058498 pth Escherichia coli str. K-12 substr. DH10B peptidyl-tRNA hydrolase YP_001730152.1 1297393 R 316385 CDS YP_001730153.1 170080833 6058502 1298255..1298533 1 NC_010473.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1298533 ychH 6058502 ychH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730153.1 1298255 D 316385 CDS YP_001730154.1 170080834 6058493 complement(1298588..1300267) 1 NC_010473.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM 1300267 ychM 6058493 ychM Escherichia coli str. K-12 substr. DH10B putative sulfate transporter YchM YP_001730154.1 1298588 R 316385 CDS YP_001730155.1 170080835 6058488 complement(1300392..1301339) 1 NC_010473.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1301339 prsA 6058488 prsA Escherichia coli str. K-12 substr. DH10B ribose-phosphate pyrophosphokinase YP_001730155.1 1300392 R 316385 CDS YP_001730156.1 170080836 6058489 complement(1301490..1302341) 1 NC_010473.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1302341 ipk 6058489 ipk Escherichia coli str. K-12 substr. DH10B 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001730156.1 1301490 R 316385 CDS YP_001730157.1 170080837 6058486 complement(1302341..1302964) 1 NC_010473.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1302964 lolB 6058486 lolB Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein LolB YP_001730157.1 1302341 R 316385 CDS YP_001730158.1 170080838 6058490 1303178..1304434 1 NC_010473.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1304434 hemA 6058490 hemA Escherichia coli str. K-12 substr. DH10B glutamyl-tRNA reductase YP_001730158.1 1303178 D 316385 CDS YP_001730159.1 170080839 6058479 1304476..1305558 1 NC_010473.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1305558 prfA 6058479 prfA Escherichia coli str. K-12 substr. DH10B peptide chain release factor 1 YP_001730159.1 1304476 D 316385 CDS YP_001730160.1 170080840 6058480 1305558..1306391 1 NC_010473.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1306391 prmC 6058480 prmC Escherichia coli str. K-12 substr. DH10B N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001730160.1 1305558 D 316385 CDS YP_001730161.1 170080841 6058478 1306388..1306780 1 NC_010473.1 putative transcriptional regulator 1306780 ychQ 6058478 ychQ Escherichia coli str. K-12 substr. DH10B putative transcriptional regulator YP_001730161.1 1306388 D 316385 CDS YP_001730162.1 170080842 6058484 1306784..1307593 1 NC_010473.1 putative transcriptional regulator 1307593 ychA 6058484 ychA Escherichia coli str. K-12 substr. DH10B putative transcriptional regulator YP_001730162.1 1306784 D 316385 CDS YP_001730163.1 170080843 6058506 1307629..1308483 1 NC_010473.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1308483 kdsA 6058506 kdsA Escherichia coli str. K-12 substr. DH10B 2-dehydro-3-deoxyphosphooctonate aldolase YP_001730163.1 1307629 D 316385 CDS YP_001730164.1 170080844 6058496 complement(1308632..1308739) 1 NC_010473.1 toxic polypeptide, small 1308739 ldrA 6058496 ldrA Escherichia coli str. K-12 substr. DH10B toxic polypeptide, small YP_001730164.1 1308632 R 316385 CDS YP_001730165.1 170080845 6062123 complement(1309167..1309274) 1 NC_010473.1 toxic polypeptide, small 1309274 ldrB 6062123 ldrB Escherichia coli str. K-12 substr. DH10B toxic polypeptide, small YP_001730165.1 1309167 R 316385 CDS YP_001730166.1 170080846 6059541 complement(1309702..1309809) 1 NC_010473.1 toxic polypeptide, small 1309809 ldrC 6059541 ldrC Escherichia coli str. K-12 substr. DH10B toxic polypeptide, small YP_001730166.1 1309702 R 316385 CDS YP_001730167.1 170080847 6061868 complement(1310213..1311313) 1 NC_010473.1 calcium/sodium:proton antiporter 1311313 chaA 6061868 chaA Escherichia coli str. K-12 substr. DH10B calcium/sodium:proton antiporter YP_001730167.1 1310213 R 316385 CDS YP_001730168.1 170080848 6058469 1311583..1311813 1 NC_010473.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1311813 chaB 6058469 chaB Escherichia coli str. K-12 substr. DH10B cation transport regulator YP_001730168.1 1311583 D 316385 CDS YP_001730169.1 170080849 6058475 1311971..1312666 1 NC_010473.1 regulatory protein for cation transport 1312666 chaC 6058475 chaC Escherichia coli str. K-12 substr. DH10B regulatory protein for cation transport YP_001730169.1 1311971 D 316385 CDS YP_001730170.1 170080850 6058467 complement(1312710..1313063) 1 NC_010473.1 hypothetical protein 1313063 ychN 6058467 ychN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730170.1 1312710 R 316385 CDS YP_001730171.1 170080851 6058448 1313248..1314642 1 NC_010473.1 hypothetical protein 1314642 ychO 6058448 ychO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730171.1 1313248 D 316385 CDS YP_001730172.1 170080852 6058454 complement(1314643..1315293) 1 NC_010473.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1315293 narL 6058454 narL Escherichia coli str. K-12 substr. DH10B transcriptional regulator NarL YP_001730172.1 1314643 R 316385 CDS YP_001730173.1 170080853 6058446 complement(1315286..1317082) 1 NC_010473.1 nitrate/nitrite sensor protein NarX 1317082 narX 6058446 narX Escherichia coli str. K-12 substr. DH10B nitrate/nitrite sensor protein NarX YP_001730173.1 1315286 R 316385 CDS YP_001730174.1 170080854 6058441 1317421..1318812 1 NC_010473.1 nitrate/nitrite transporter 1318812 narK 6058441 narK Escherichia coli str. K-12 substr. DH10B nitrate/nitrite transporter YP_001730174.1 1317421 D 316385 CDS YP_001730175.1 170080855 6058442 1319328..1323071 1 NC_010473.1 nitrate reductase 1 subunit alpha 1323071 narG 6058442 narG Escherichia coli str. K-12 substr. DH10B nitrate reductase 1 subunit alpha YP_001730175.1 1319328 D 316385 CDS YP_001730176.1 170080856 6058440 1323068..1324606 1 NC_010473.1 nitrate reductase 1 subunit, beta (Fe-S) 1324606 narH 6058440 narH Escherichia coli str. K-12 substr. DH10B nitrate reductase 1 subunit, beta (Fe-S) YP_001730176.1 1323068 D 316385 CDS YP_001730177.1 170080857 6058445 1324603..1325313 1 NC_010473.1 molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 1325313 narJ 6058445 narJ Escherichia coli str. K-12 substr. DH10B molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 YP_001730177.1 1324603 D 316385 CDS YP_001730178.1 170080858 6058432 1325313..1325990 1 NC_010473.1 nitrate reductase 1 subunit gamma (cytochrome b(NR)) 1325990 narI 6058432 narI Escherichia coli str. K-12 substr. DH10B nitrate reductase 1 subunit gamma (cytochrome b(NR)) YP_001730178.1 1325313 D 316385 CDS YP_001730179.1 170080859 6058433 1326173..1326448 1 NC_010473.1 hypothetical protein 1326448 ychS 6058433 ychS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730179.1 1326173 D 316385 CDS YP_001730180.1 170080860 6059178 complement(1326551..1326640) 1 NC_010473.1 putative protamine-like protein 1326640 tpr 6059178 tpr Escherichia coli str. K-12 substr. DH10B putative protamine-like protein YP_001730180.1 1326551 R 316385 CDS YP_001730181.1 170080861 6062204 complement(1327246..1328088) 1 NC_010473.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1328088 purU 6062204 purU Escherichia coli str. K-12 substr. DH10B formyltetrahydrofolate deformylase YP_001730181.1 1327246 R 316385 CDS YP_001730182.1 170080862 6058458 complement(1328138..1328596) 1 NC_010473.1 hypothetical protein 1328596 ychJ 6058458 ychJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730182.1 1328138 R 316385 CDS YP_001730183.1 170080863 6058447 1328670..1329614 1 NC_010473.1 hypothetical protein 1329614 rssA 6058447 rssA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730183.1 1328670 D 316385 CDS YP_001730184.1 170080864 6058424 1329706..1330719 1 NC_010473.1 response regulator of RpoS 1330719 rssB 6058424 rssB Escherichia coli str. K-12 substr. DH10B response regulator of RpoS YP_001730184.1 1329706 D 316385 CDS YP_001730185.1 170080865 6058428 1330921..1331829 1 NC_010473.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1331829 galU 6058428 galU Escherichia coli str. K-12 substr. DH10B UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_001730185.1 1330921 D 316385 CDS YP_001730186.1 170080866 6058415 complement(1331973..1332386) 1 NC_010473.1 global DNA-binding transcriptional dual regulator H-NS 1332386 hns 6058415 hns Escherichia coli str. K-12 substr. DH10B global DNA-binding transcriptional dual regulator H-NS YP_001730186.1 1331973 R 316385 CDS YP_001730187.1 170080867 6058419 1332991..1333608 1 NC_010473.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1333608 tdk 6058419 tdk Escherichia coli str. K-12 substr. DH10B thymidine kinase YP_001730187.1 1332991 D 316385 CDS YP_001730188.1 170080868 6062148 complement(1334910..1337585) 1 NC_010473.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1337585 adhE 6062148 adhE Escherichia coli str. K-12 substr. DH10B bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_001730188.1 1334910 R 316385 CDS YP_001730189.1 170080869 6058411 1338062..1338709 1 NC_010473.1 hypothetical protein 1338709 ychE 6058411 ychE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730189.1 1338062 D 316385 CDS YP_001730190.1 170080870 6058404 1340224..1341855 1 NC_010473.1 contains the nonsynonymous change N271Y; oligopeptide transporter periplasmic subunit 1341855 oppA 6058404 oppA Escherichia coli str. K-12 substr. DH10B oligopeptide transporter periplasmic subunit YP_001730190.1 1340224 D 316385 CDS YP_001730191.1 170080871 6058406 1341941..1342861 1 NC_010473.1 oligopeptide transporter permease 1342861 oppB 6058406 oppB Escherichia coli str. K-12 substr. DH10B oligopeptide transporter permease YP_001730191.1 1341941 D 316385 CDS YP_001730192.1 170080872 6058402 1342876..1343784 1 NC_010473.1 oligopeptide ABC transporter membrane protein 1343784 oppC 6058402 oppC Escherichia coli str. K-12 substr. DH10B oligopeptide ABC transporter membrane protein YP_001730192.1 1342876 D 316385 CDS YP_001730193.1 170080873 6058393 1343796..1344809 1 NC_010473.1 oligopeptide ABC transporter ATP-binding protein 1344809 oppD 6058393 oppD Escherichia coli str. K-12 substr. DH10B oligopeptide ABC transporter ATP-binding protein YP_001730193.1 1343796 D 316385 CDS YP_001730194.1 170080874 6058398 1344806..1345810 1 NC_010473.1 contains the nonsynonymous change S325A; ATP-binding subunit of oligopeptide ABC transporter 1345810 oppF 6058398 oppF Escherichia coli str. K-12 substr. DH10B ATP-binding subunit of oligopeptide ABC transporter YP_001730194.1 1344806 D 316385 CDS YP_001730195.1 170080875 6058392 complement(1345863..1346192) 1 NC_010473.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1346192 yciU 6058392 yciU Escherichia coli str. K-12 substr. DH10B dsDNA-mimic protein YP_001730195.1 1345863 R 316385 CDS YP_001730196.1 170080876 6058400 complement(1346227..1347687) 1 NC_010473.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1347687 cls 6058400 cls Escherichia coli str. K-12 substr. DH10B cardiolipin synthetase YP_001730196.1 1346227 R 316385 CDS YP_001730197.1 170080877 6058380 complement(1348058..1349311) 1 NC_010473.1 voltage-gated potassium channel 1349311 kch 6058380 kch Escherichia coli str. K-12 substr. DH10B voltage-gated potassium channel YP_001730197.1 1348058 R 316385 CDS YP_001730198.1 170080878 6058384 1349759..1351009 1 NC_010473.1 integrase 1351009 int 6058384 int Escherichia coli str. K-12 substr. DH10B integrase YP_001730198.1 1349759 D 316385 CDS YP_001730199.1 170080879 6058375 complement(1351006..1351203) 1 NC_010473.1 excisionase 1351203 xis 6058375 xis Escherichia coli str. K-12 substr. DH10B excisionase YP_001730199.1 1351006 R 316385 CDS YP_001730200.1 170080880 6058389 complement(1351245..1351490) 1 NC_010473.1 hypothetical protein 1351490 6058389 ECDH10B_1315 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730200.1 1351245 R 316385 CDS YP_001730201.1 170080881 6060027 complement(1352518..1352952) 1 NC_010473.1 hypothetical protein 1352952 6060027 ECDH10B_1317 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730201.1 1352518 R 316385 CDS YP_001730202.1 170080882 6058403 complement(1352943..1353623) 1 NC_010473.1 exonuclease 1353623 exo 6058403 exo Escherichia coli str. K-12 substr. DH10B exonuclease YP_001730202.1 1352943 R 316385 CDS YP_001730203.1 170080883 6058369 complement(1353620..1354537) 1 NC_010473.1 RecT protein 1354537 bet 6058369 bet Escherichia coli str. K-12 substr. DH10B RecT protein YP_001730203.1 1353620 R 316385 CDS YP_001730204.1 170080884 6058371 complement(1354547..1354828) 1 NC_010473.1 hypothetical protein 1354828 6058371 ECDH10B_1320 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730204.1 1354547 R 316385 CDS YP_001730205.1 170080885 6058367 complement(1354836..1355804) 1 NC_010473.1 hypothetical protein 1355804 6058367 ECDH10B_1321 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730205.1 1354836 R 316385 CDS YP_001730206.1 170080886 6058368 complement(1355909..1356799) 1 NC_010473.1 hypothetical protein 1356799 6058368 ECDH10B_1322 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730206.1 1355909 R 316385 CDS YP_001730207.1 170080887 6058374 complement(1356756..1356965) 1 NC_010473.1 Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division; FtsZ inhibitor protein 1356965 kil 6058374 kil Escherichia coli str. K-12 substr. DH10B FtsZ inhibitor protein YP_001730207.1 1356756 R 316385 CDS YP_001730208.1 170080888 6058366 complement(1356962..1357162) 1 NC_010473.1 hypothetical protein 1357162 6058366 ECDH10B_1324 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730208.1 1356962 R 316385 CDS YP_001730209.1 170080889 6058360 complement(1357122..1357331) 1 NC_010473.1 hypothetical protein 1357331 6058360 ECDH10B_1325 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730209.1 1357122 R 316385 CDS YP_001730210.1 170080890 6058361 complement(1357487..1357783) 1 NC_010473.1 regulatory protein N 1357783 N 6058361 N Escherichia coli str. K-12 substr. DH10B regulatory protein N YP_001730210.1 1357487 R 316385 CDS YP_001730211.1 170080891 6058358 complement(1358581..1359447) 1 NC_010473.1 protein 40A 1359447 40 6058358 40 Escherichia coli str. K-12 substr. DH10B protein 40A YP_001730211.1 1358581 R 316385 CDS YP_001730212.1 170080892 6058345 complement(1359584..1360294) 1 NC_010473.1 repressor protein CI 1360294 cI 6058345 cI Escherichia coli str. K-12 substr. DH10B repressor protein CI YP_001730212.1 1359584 R 316385 CDS YP_001730213.1 170080893 6058355 1360412..1360633 1 NC_010473.1 regulatory protein 30 (Cro) 1360633 30 6058355 30 Escherichia coli str. K-12 substr. DH10B regulatory protein 30 (Cro) YP_001730213.1 1360412 D 316385 CDS YP_001730214.1 170080894 6058344 1360808..1361206 1 NC_010473.1 regulatory protein CII 1361206 cII 6058344 cII Escherichia coli str. K-12 substr. DH10B regulatory protein CII YP_001730214.1 1360808 D 316385 CDS YP_001730215.1 170080895 6058357 1361292..1362200 1 NC_010473.1 replication protein 15 (O) 1362200 6058357 ECDH10B_1331 Escherichia coli str. K-12 substr. DH10B replication protein 15 (O) YP_001730215.1 1361292 D 316385 CDS YP_001730216.1 170080896 6058341 1362197..1362886 1 NC_010473.1 replication protein 14 (P) 1362886 6058341 ECDH10B_1332 Escherichia coli str. K-12 substr. DH10B replication protein 14 (P) YP_001730216.1 1362197 D 316385 CDS YP_001730217.1 170080897 6058342 1362950..1363669 1 NC_010473.1 hypothetical protein 1363669 6058342 ECDH10B_1333 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730217.1 1362950 D 316385 CDS YP_001730218.1 170080898 6058340 1363842..1364345 1 NC_010473.1 DLP12 prophage; hypothetical protein 1364345 6058340 ECDH10B_1334 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730218.1 1363842 D 316385 CDS YP_001730219.1 170080899 6058343 1364512..1365180 1 NC_010473.1 serine/threonine-protein phosphatase 1365180 6058343 ECDH10B_1335 Escherichia coli str. K-12 substr. DH10B serine/threonine-protein phosphatase YP_001730219.1 1364512 D 316385 CDS YP_001730220.1 170080900 6058364 1365173..1365814 1 NC_010473.1 structure-specific endonuclease 1365814 rap 6058364 rap Escherichia coli str. K-12 substr. DH10B structure-specific endonuclease YP_001730220.1 1365173 D 316385 CDS YP_001730221.1 170080901 6058359 1366130..1366939 1 NC_010473.1 prophage antitermination protein 1366939 17 6058359 17 Escherichia coli str. K-12 substr. DH10B prophage antitermination protein YP_001730221.1 1366130 D 316385 CDS YP_001730222.1 170080902 6058331 1367418..1367642 1 NC_010473.1 lysis S family protein 1367642 18 6058331 18 Escherichia coli str. K-12 substr. DH10B lysis S family protein YP_001730222.1 1367418 D 316385 CDS YP_001730223.1 170080903 6058333 1367620..1368114 1 NC_010473.1 lysozyme-like protein 1368114 19 6058333 19 Escherichia coli str. K-12 substr. DH10B lysozyme-like protein YP_001730223.1 1367620 D 316385 CDS YP_001730224.1 170080904 6058325 1368111..1368569 1 NC_010473.1 Rz lysis protein 1368569 Rz 6058325 Rz Escherichia coli str. K-12 substr. DH10B Rz lysis protein YP_001730224.1 1368111 D 316385 CDS YP_001730225.1 170080905 6058328 1368331..1368516 1 NC_010473.1 putative lysis protein 1368516 Rz1 6058328 Rz1 Escherichia coli str. K-12 substr. DH10B putative lysis protein YP_001730225.1 1368331 D 316385 CDS YP_001730226.1 170080906 6058338 1368732..1369286 1 NC_010473.1 Rha protein 1369286 rha 6058338 rha Escherichia coli str. K-12 substr. DH10B Rha protein YP_001730226.1 1368732 D 316385 CDS YP_001730227.1 170080907 6058324 complement(1369358..1369972) 1 NC_010473.1 hypothetical protein 1369972 6058324 ECDH10B_1343 Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730227.1 1369358 R 316385 CDS YP_001730228.1 170080908 6058320 1369953..1370183 1 NC_010473.1 putative Fur-regulated protein 1370183 6058320 ECDH10B_1344 Escherichia coli str. K-12 substr. DH10B putative Fur-regulated protein YP_001730228.1 1369953 D 316385 CDS YP_001730229.1 170080909 6058322 1370345..1371073 1 NC_010473.1 putative Fur-regulated protein 1371073 6058322 ECDH10B_1345 Escherichia coli str. K-12 substr. DH10B putative Fur-regulated protein YP_001730229.1 1370345 D 316385 CDS YP_001730230.1 170080910 6058308 1371321..1371866 1 NC_010473.1 phage DNA packaging protein Nu1 1371866 6058308 ECDH10B_1346 Escherichia coli str. K-12 substr. DH10B phage DNA packaging protein Nu1 YP_001730230.1 1371321 D 316385 CDS YP_001730231.1 170080911 6058305 1371841..1373763 1 NC_010473.1 DNA packaging protein 1373763 2 6058305 2 Escherichia coli str. K-12 substr. DH10B DNA packaging protein YP_001730231.1 1371841 D 316385 CDS YP_001730232.1 170080912 6058306 1373763..1373969 1 NC_010473.1 head-to-tail joining protein 1373969 W 6058306 W Escherichia coli str. K-12 substr. DH10B head-to-tail joining protein YP_001730232.1 1373763 D 316385 CDS YP_001730233.1 170080913 6058304 1373966..1375558 1 NC_010473.1 head portal protein 1375558 B 6058304 B Escherichia coli str. K-12 substr. DH10B head portal protein YP_001730233.1 1373966 D 316385 CDS YP_001730234.1 170080914 6058307 1375539..1376882 1 NC_010473.1 head protein 1376882 C 6058307 C Escherichia coli str. K-12 substr. DH10B head protein YP_001730234.1 1375539 D 316385 CDS YP_001730235.1 170080915 6058299 1376892..1377224 1 NC_010473.1 head decoration protein; major capsid protein 1377224 D 6058299 D Escherichia coli str. K-12 substr. DH10B head decoration protein; major capsid protein YP_001730235.1 1376892 D 316385 CDS YP_001730236.1 170080916 6061990 1378249..1378719 1 NC_010473.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 1378719 cynS 6061990 cynS Escherichia coli str. K-12 substr. DH10B cyanate hydratase YP_001730236.1 1378249 D 316385 CDS YP_001730237.1 170080917 6058298 1378752..1379906 1 NC_010473.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; putative cyanate transporter 1379906 cynX 6058298 cynX Escherichia coli str. K-12 substr. DH10B putative cyanate transporter YP_001730237.1 1378752 D 316385 CDS YP_001730238.1 170080918 6058302 complement(1380009..1380620) 1 NC_010473.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 1380620 lacA 6058302 lacA Escherichia coli str. K-12 substr. DH10B galactoside O-acetyltransferase YP_001730238.1 1380009 R 316385 CDS YP_001730239.1 170080919 6058323 complement(1380686..1381939) 1 NC_010473.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 1381939 lacY 6058323 lacY Escherichia coli str. K-12 substr. DH10B galactoside permease YP_001730239.1 1380686 R 316385 CDS YP_001730240.1 170080920 6058312 complement(1385095..1386177) 1 NC_010473.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 1386177 lacI 6058312 lacI Escherichia coli str. K-12 substr. DH10B lac repressor YP_001730240.1 1385095 R 316385 CDS YP_001730241.1 170080921 6058293 complement(1386254..1387201) 1 NC_010473.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR 1387201 mhpR 6058293 mhpR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator MhpR YP_001730241.1 1386254 R 316385 CDS YP_001730242.1 170080922 6058294 1387278..1388942 1 NC_010473.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 1388942 mhpA 6058294 mhpA Escherichia coli str. K-12 substr. DH10B 3-(3-hydroxyphenyl)propionate hydroxylase YP_001730242.1 1387278 D 316385 CDS YP_001730243.1 170080923 6058289 1388944..1389888 1 NC_010473.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 1389888 mhpB 6058289 mhpB Escherichia coli str. K-12 substr. DH10B 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_001730243.1 1388944 D 316385 CDS YP_001730244.1 170080924 6058291 1389891..1390772 1 NC_010473.1 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 1390772 mhpC 6058291 mhpC Escherichia coli str. K-12 substr. DH10B 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_001730244.1 1389891 D 316385 CDS YP_001730245.1 170080925 6058296 complement(1391119..1393215) 1 NC_010473.1 hypothetical protein 1393215 tnpX 6058296 tnpX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730245.1 1391119 R 316385 CDS YP_001730246.1 170080926 6059378 complement(1393231..1393782) 1 NC_010473.1 resolvase 1393782 tnpR 6059378 tnpR Escherichia coli str. K-12 substr. DH10B resolvase YP_001730246.1 1393231 R 316385 CDS YP_001730247.1 170080927 6058286 1393946..1396954 1 NC_010473.1 transposase 1396954 tnpA 6058286 tnpA Escherichia coli str. K-12 substr. DH10B transposase YP_001730247.1 1393946 D 316385 CDS YP_001730248.1 170080928 6062101 complement(1397989..1398285) 1 NC_010473.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1398285 yciI 6062101 yciI Escherichia coli str. K-12 substr. DH10B YciI-like protein YP_001730248.1 1397989 R 316385 CDS YP_001730249.1 170080929 6058282 1398509..1399228 1 NC_010473.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1399228 tonB 6058282 tonB Escherichia coli str. K-12 substr. DH10B transporter YP_001730249.1 1398509 D 316385 CDS YP_001730250.1 170080930 6058277 complement(1399268..1399666) 1 NC_010473.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1399666 yciA 6058277 yciA Escherichia coli str. K-12 substr. DH10B acyl-CoA thioester hydrolase YP_001730250.1 1399268 R 316385 CDS YP_001730251.1 170080931 6058270 complement(1399771..1400310) 1 NC_010473.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1400310 yciB 6058270 yciB Escherichia coli str. K-12 substr. DH10B intracellular septation protein A YP_001730251.1 1399771 R 316385 CDS YP_001730252.1 170080932 6058273 complement(1400340..1401083) 1 NC_010473.1 hypothetical protein 1401083 yciC 6058273 yciC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730252.1 1400340 R 316385 CDS YP_001730253.1 170080933 6058269 1401440..1402078 1 NC_010473.1 receptor for colicin S4; outer membrane protein W 1402078 ompW 6058269 ompW Escherichia coli str. K-12 substr. DH10B outer membrane protein W YP_001730253.1 1401440 D 316385 CDS YP_001730254.1 170080934 6058275 complement(1402138..1402644) 1 NC_010473.1 hypothetical protein 1402644 yciE 6058275 yciE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730254.1 1402138 R 316385 CDS YP_001730255.1 170080935 6058259 complement(1402690..1403190) 1 NC_010473.1 hypothetical protein 1403190 yciF 6058259 yciF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730255.1 1402690 R 316385 CDS YP_001730256.1 170080936 6058262 complement(1403276..1403455) 1 NC_010473.1 hypothetical protein 1403455 yciG 6058262 yciG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730256.1 1403276 R 316385 CDS YP_001730257.1 170080937 6058258 complement(1403836..1404642) 1 NC_010473.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1404642 trpA 6058258 trpA Escherichia coli str. K-12 substr. DH10B tryptophan synthase subunit alpha YP_001730257.1 1403836 R 316385 CDS YP_001730258.1 170080938 6058265 complement(1404642..1405835) 1 NC_010473.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1405835 trpB 6058265 trpB Escherichia coli str. K-12 substr. DH10B tryptophan synthase subunit beta YP_001730258.1 1404642 R 316385 CDS YP_001730259.1 170080939 6058285 complement(1405847..1407205) 1 NC_010473.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1407205 trpC 6058285 trpC Escherichia coli str. K-12 substr. DH10B bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_001730259.1 1405847 R 316385 CDS YP_001730260.1 170080940 6058280 complement(1407209..1408804) 1 NC_010473.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1408804 trpD 6058280 trpD Escherichia coli str. K-12 substr. DH10B bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_001730260.1 1407209 R 316385 CDS YP_001730261.1 170080941 6058250 complement(1408804..1410366) 1 NC_010473.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1410366 trpE 6058250 trpE Escherichia coli str. K-12 substr. DH10B anthranilate synthase component I YP_001730261.1 1408804 R 316385 CDS YP_001730263.1 170080943 6058247 1410640..1411521 1 NC_010473.1 hypothetical protein 1411521 trpH 6058247 trpH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730263.1 1410640 D 316385 CDS YP_001730264.1 170080944 6058248 1411518..1412138 1 NC_010473.1 hypothetical protein 1412138 yciO 6058248 yciO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730264.1 1411518 D 316385 CDS YP_001730265.1 170080945 6058254 1412166..1414061 1 NC_010473.1 inner membrane protein 1414061 yciQ 6058254 yciQ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730265.1 1412166 D 316385 CDS YP_001730266.1 170080946 6058246 1414272..1415147 1 NC_010473.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1415147 rluB 6058246 rluB Escherichia coli str. K-12 substr. DH10B 23S rRNA pseudouridylate synthase B YP_001730266.1 1414272 D 316385 CDS YP_001730267.1 170080947 6058243 complement(1415187..1415777) 1 NC_010473.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1415777 btuR 6058243 btuR Escherichia coli str. K-12 substr. DH10B cob(I)yrinic acid a,c-diamide adenosyltransferase YP_001730267.1 1415187 R 316385 CDS YP_001730268.1 170080948 6058244 complement(1415774..1416532) 1 NC_010473.1 short chain dehydrogenase 1416532 yciK 6058244 yciK Escherichia coli str. K-12 substr. DH10B short chain dehydrogenase YP_001730268.1 1415774 R 316385 CDS YP_001730269.1 170080949 6058240 1416752..1417801 1 NC_010473.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1417801 sohB 6058240 sohB Escherichia coli str. K-12 substr. DH10B putative periplasmic protease YP_001730269.1 1416752 D 316385 CDS YP_001730270.1 170080950 6058233 complement(1417837..1418088) 1 NC_010473.1 hypothetical protein 1418088 yciN 6058233 yciN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730270.1 1417837 R 316385 CDS YP_001730271.1 170080951 6058235 1418468..1421065 1 NC_010473.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1421065 topA 6058235 topA Escherichia coli str. K-12 substr. DH10B DNA topoisomerase I YP_001730271.1 1418468 D 316385 CDS YP_001730272.1 170080952 6058232 1421275..1422249 1 NC_010473.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1422249 cysB 6058232 cysB Escherichia coli str. K-12 substr. DH10B transcriptional regulator CysB YP_001730272.1 1421275 D 316385 CDS YP_001730273.1 170080953 6058238 1422580..1422708 1 NC_010473.1 hypothetical protein 1422708 ymiA 6058238 ymiA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730273.1 1422580 D 316385 CDS YP_001730274.1 170080954 6058218 1422711..1422878 1 NC_010473.1 hypothetical protein 1422878 yciX 6058218 yciX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730274.1 1422711 D 316385 CDS YP_001730275.1 170080955 6058220 1423251..1425926 1 NC_010473.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1425926 acnA 6058220 acnA Escherichia coli str. K-12 substr. DH10B aconitate hydratase YP_001730275.1 1423251 D 316385 CDS YP_001730276.1 170080956 6058217 complement(1425990..1426580) 1 NC_010473.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1426580 ribA 6058217 ribA Escherichia coli str. K-12 substr. DH10B GTP cyclohydrolase II YP_001730276.1 1425990 R 316385 CDS YP_001730277.1 170080957 6058225 1426750..1427514 1 NC_010473.1 phosphatidylglycerophosphatase B 1427514 pgpB 6058225 pgpB Escherichia coli str. K-12 substr. DH10B phosphatidylglycerophosphatase B YP_001730277.1 1426750 D 316385 CDS YP_001730278.1 170080958 6058245 1427663..1427971 1 NC_010473.1 inner membrane protein 1427971 yciS 6058245 yciS Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730278.1 1427663 D 316385 CDS YP_001730279.1 170080959 6058241 1427978..1429147 1 NC_010473.1 tetratricopeptide repeat protein 1429147 yciM 6058241 yciM Escherichia coli str. K-12 substr. DH10B tetratricopeptide repeat protein YP_001730279.1 1427978 D 316385 CDS YP_001730280.1 170080960 6058210 1429341..1430078 1 NC_010473.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1430078 pyrF 6058210 pyrF Escherichia coli str. K-12 substr. DH10B orotidine 5'-phosphate decarboxylase YP_001730280.1 1429341 D 316385 CDS YP_001730281.1 170080961 6058214 1430078..1430404 1 NC_010473.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1430404 yciH 6058214 yciH Escherichia coli str. K-12 substr. DH10B translation initiation factor Sui1 YP_001730281.1 1430078 D 316385 CDS YP_001730282.1 170080962 6058208 complement(1430530..1430748) 1 NC_010473.1 lipoprotein 1430748 osmB 6058208 osmB Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730282.1 1430530 R 316385 CDS YP_001730283.1 170080963 6058209 complement(1431017..1431766) 1 NC_010473.1 DNA-binding transcriptional regulator 1431766 yciT 6058209 yciT Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730283.1 1431017 R 316385 CDS YP_001730284.1 170080964 6058215 complement(1432177..1434162) 1 NC_010473.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1434162 gmr 6058215 gmr Escherichia coli str. K-12 substr. DH10B RNase II stability modulator YP_001730284.1 1432177 R 316385 CDS YP_001730285.1 170080965 6058207 complement(1434398..1436332) 1 NC_010473.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1436332 rnb 6058207 rnb Escherichia coli str. K-12 substr. DH10B exoribonuclease II YP_001730285.1 1434398 R 316385 CDS YP_001730286.1 170080966 6058201 complement(1436400..1437527) 1 NC_010473.1 oxidoreductase 1437527 yciW 6058201 yciW Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001730286.1 1436400 R 316385 CDS YP_001730287.1 170080967 6058204 complement(1437671..1438459) 1 NC_010473.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 1438459 fabI 6058204 fabI Escherichia coli str. K-12 substr. DH10B enoyl-(acyl carrier protein) reductase YP_001730287.1 1437671 R 316385 CDS YP_001730288.1 170080968 6058198 complement(1438827..1439180) 1 NC_010473.1 hypothetical protein 1439180 ycjD 6058198 ycjD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730288.1 1438827 R 316385 CDS YP_001730289.1 170080969 6058190 complement(1439248..1440054) 1 NC_010473.1 antibiotic ABC transporter ATP-binding protein 1440054 sapF 6058190 sapF Escherichia coli str. K-12 substr. DH10B antibiotic ABC transporter ATP-binding protein YP_001730289.1 1439248 R 316385 CDS YP_001730290.1 170080970 6058196 complement(1440056..1441048) 1 NC_010473.1 antibiotic ABC transporter ATP-binding protein 1441048 sapD 6058196 sapD Escherichia coli str. K-12 substr. DH10B antibiotic ABC transporter ATP-binding protein YP_001730290.1 1440056 R 316385 CDS YP_001730291.1 170080971 6058187 complement(1441048..1441938) 1 NC_010473.1 antibiotic ABC transporter transmembrane protein 1441938 sapC 6058187 sapC Escherichia coli str. K-12 substr. DH10B antibiotic ABC transporter transmembrane protein YP_001730291.1 1441048 R 316385 CDS YP_001730292.1 170080972 6058197 complement(1441925..1442890) 1 NC_010473.1 antibiotic ABC transporter transmembrane protein 1442890 sapB 6058197 sapB Escherichia coli str. K-12 substr. DH10B antibiotic ABC transporter transmembrane protein YP_001730292.1 1441925 R 316385 CDS YP_001730293.1 170080973 6058182 complement(1442887..1444530) 1 NC_010473.1 antibiotic ABC transporter periplasmic-binding protein 1444530 sapA 6058182 sapA Escherichia coli str. K-12 substr. DH10B antibiotic ABC transporter periplasmic-binding protein YP_001730293.1 1442887 R 316385 CDS YP_001730294.1 170080974 6058183 complement(1444843..1445088) 1 NC_010473.1 hypothetical protein 1445088 ymjA 6058183 ymjA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730294.1 1444843 R 316385 CDS YP_001730295.1 170080975 6058181 complement(1445222..1446607) 1 NC_010473.1 contains the nonsynonymous change Y110C; putrescine importer 1446607 puuP 6058181 puuP Escherichia coli str. K-12 substr. DH10B putrescine importer YP_001730295.1 1445222 R 316385 CDS YP_001730296.1 170080976 6058184 complement(1446910..1448328) 1 NC_010473.1 gamma-Glu-putrescine synthase 1448328 puuA 6058184 puuA Escherichia coli str. K-12 substr. DH10B gamma-Glu-putrescine synthase YP_001730296.1 1446910 R 316385 CDS YP_001730297.1 170080977 6058206 1448540..1449304 1 NC_010473.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1449304 puuD 6058206 puuD Escherichia coli str. K-12 substr. DH10B gamma-glutamyl-gamma-aminobutyrate hydrolase YP_001730297.1 1448540 D 316385 CDS YP_001730298.1 170080978 6058199 1449331..1449888 1 NC_010473.1 regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1449888 puuR 6058199 puuR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor PuuR YP_001730298.1 1449331 D 316385 CDS YP_001730299.1 170080979 6058177 1450163..1451650 1 NC_010473.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1451650 puuC 6058177 puuC Escherichia coli str. K-12 substr. DH10B gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_001730299.1 1450163 D 316385 CDS YP_001730300.1 170080980 6058178 1451652..1452932 1 NC_010473.1 gamma-Glu-putrescine oxidase 1452932 puuB 6058178 puuB Escherichia coli str. K-12 substr. DH10B gamma-Glu-putrescine oxidase YP_001730300.1 1451652 D 316385 CDS YP_001730301.1 170080981 6058174 1452970..1454235 1 NC_010473.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1454235 puuE 6058174 puuE Escherichia coli str. K-12 substr. DH10B 4-aminobutyrate transaminase YP_001730301.1 1452970 D 316385 CDS YP_001730302.1 170080982 6058175 complement(1454355..1455332) 1 NC_010473.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1455332 pspF 6058175 pspF Escherichia coli str. K-12 substr. DH10B phage shock protein operon transcriptional activator YP_001730302.1 1454355 R 316385 CDS YP_001730303.1 170080983 6058179 1455499..1456167 1 NC_010473.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1456167 pspA 6058179 pspA Escherichia coli str. K-12 substr. DH10B phage shock protein PspA YP_001730303.1 1455499 D 316385 CDS YP_001730304.1 170080984 6058173 1456221..1456445 1 NC_010473.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1456445 pspB 6058173 pspB Escherichia coli str. K-12 substr. DH10B phage shock protein B YP_001730304.1 1456221 D 316385 CDS YP_001730305.1 170080985 6058165 1456445..1456804 1 NC_010473.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1456804 pspC 6058165 pspC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator PspC YP_001730305.1 1456445 D 316385 CDS YP_001730306.1 170080986 6058166 1456813..1457034 1 NC_010473.1 peripheral inner membrane phage-shock protein 1457034 pspD 6058166 pspD Escherichia coli str. K-12 substr. DH10B peripheral inner membrane phage-shock protein YP_001730306.1 1456813 D 316385 CDS YP_001730307.1 170080987 6058162 1457109..1457423 1 NC_010473.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1457423 pspE 6058162 pspE Escherichia coli str. K-12 substr. DH10B thiosulfate:cyanide sulfurtransferase YP_001730307.1 1457109 D 316385 CDS YP_001730308.1 170080988 6058159 1457636..1459315 1 NC_010473.1 glucosyltransferase 1459315 ycjM 6058159 ycjM Escherichia coli str. K-12 substr. DH10B glucosyltransferase YP_001730308.1 1457636 D 316385 CDS YP_001730309.1 170080989 6058160 1459329..1460621 1 NC_010473.1 sugar ABC transporter periplasmic-binding protein 1460621 ycjN 6058160 ycjN Escherichia coli str. K-12 substr. DH10B sugar ABC transporter periplasmic-binding protein YP_001730309.1 1459329 D 316385 CDS YP_001730310.1 170080990 6058158 1460642..1461523 1 NC_010473.1 sugar ABC transporter membrane protein 1461523 ycjO 6058158 ycjO Escherichia coli str. K-12 substr. DH10B sugar ABC transporter membrane protein YP_001730310.1 1460642 D 316385 CDS YP_001730311.1 170080991 6058161 1461510..1462352 1 NC_010473.1 sugar ABC transporter membrane protein 1462352 ycjP 6058161 ycjP Escherichia coli str. K-12 substr. DH10B sugar ABC transporter membrane protein YP_001730311.1 1461510 D 316385 CDS YP_001730312.1 170080992 6058151 1462383..1463435 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 1463435 ycjQ 6058151 ycjQ Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001730312.1 1462383 D 316385 CDS YP_001730313.1 170080993 6058155 1463454..1464242 1 NC_010473.1 hypothetical protein 1464242 ycjR 6058155 ycjR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730313.1 1463454 D 316385 CDS YP_001730314.1 170080994 6058149 1464252..1465307 1 NC_010473.1 oxidoreductase, NADH-binding 1465307 ycjS 6058149 ycjS Escherichia coli str. K-12 substr. DH10B oxidoreductase, NADH-binding YP_001730314.1 1464252 D 316385 CDS YP_001730315.1 170080995 6058157 1465304..1467571 1 NC_010473.1 hydrolase 1467571 ycjT 6058157 ycjT Escherichia coli str. K-12 substr. DH10B hydrolase YP_001730315.1 1465304 D 316385 CDS YP_001730316.1 170080996 6058168 1467568..1468227 1 NC_010473.1 beta-phosphoglucomutase 1468227 ycjU 6058168 ycjU Escherichia coli str. K-12 substr. DH10B beta-phosphoglucomutase YP_001730316.1 1467568 D 316385 CDS YP_001730317.1 170080997 6062292 1469367..1470272 1 NC_010473.1 outer membrane porin 1470272 ompG 6062292 ompG Escherichia coli str. K-12 substr. DH10B outer membrane porin YP_001730317.1 1469367 D 316385 CDS YP_001730318.1 170080998 6058144 complement(1470383..1471381) 1 NC_010473.1 DNA-binding transcriptional regulator 1471381 ycjW 6058144 ycjW Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730318.1 1470383 R 316385 CDS YP_001730319.1 170080999 6058147 1471537..1472934 1 NC_010473.1 hypothetical protein 1472934 ycjX 6058147 ycjX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730319.1 1471537 D 316385 CDS YP_001730320.1 170081000 6058141 1472931..1473992 1 NC_010473.1 hypothetical protein 1473992 ycjF 6058141 ycjF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730320.1 1472931 D 316385 CDS YP_001730321.1 170081001 6058143 1474140..1475681 1 NC_010473.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1475681 tyrR 6058143 tyrR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator TyrR YP_001730321.1 1474140 D 316385 CDS YP_001730322.1 170081002 6058148 complement(1475725..1476231) 1 NC_010473.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1476231 tpx 6058148 tpx Escherichia coli str. K-12 substr. DH10B thiol peroxidase YP_001730322.1 1475725 R 316385 CDS YP_001730323.1 170081003 6060086 1476350..1477315 1 NC_010473.1 L-Ala-D/L-Glu epimerase 1477315 ycjG 6060086 ycjG Escherichia coli str. K-12 substr. DH10B L-Ala-D/L-Glu epimerase YP_001730323.1 1476350 D 316385 CDS YP_001730324.1 170081004 6058140 complement(1477290..1478078) 1 NC_010473.1 murein peptide amidase A 1478078 mpaA 6058140 mpaA Escherichia coli str. K-12 substr. DH10B murein peptide amidase A YP_001730324.1 1477290 R 316385 CDS YP_001730325.1 170081005 6058136 complement(1478100..1478282) 1 NC_010473.1 oxidoreductase 1478282 ymjC 6058136 ymjC Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001730325.1 1478100 R 316385 CDS YP_001730326.1 170081006 6058138 complement(1478353..1479285) 1 NC_010473.1 hydrolase 1479285 ycjY 6058138 ycjY Escherichia coli str. K-12 substr. DH10B hydrolase YP_001730326.1 1478353 R 316385 CDS YP_001730327.1 170081007 6058132 1479411..1480310 1 NC_010473.1 DNA-binding transcriptional regulator 1480310 ycjZ 6058132 ycjZ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730327.1 1479411 D 316385 CDS YP_001730328.1 170081008 6058128 1480647..1482260 1 NC_010473.1 L-ala-gamma-D-glutamyl-meso-DAP ABC transporter periplasmic substrate-binding protein 1482260 mppA 6058128 mppA Escherichia coli str. K-12 substr. DH10B L-ala-gamma-D-glutamyl-meso-DAP ABC transporter periplasmic substrate-binding protein YP_001730328.1 1480647 D 316385 CDS YP_001730329.1 170081009 6058129 complement(1482311..1483342) 1 NC_010473.1 inner membrane protein 1483342 ynaI 6058129 ynaI Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730329.1 1482311 R 316385 CDS YP_001730330.1 170081010 6058127 1483496..1484512 1 NC_010473.1 IS5 transposase and trans-activator 1484512 insH-4 6058127 insH-4 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001730330.1 1483496 D 316385 CDS YP_001730331.1 170081011 6058130 1484785..1485042 1 NC_010473.1 inner membrane protein 1485042 ynaJ 6058130 ynaJ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730331.1 1484785 D 316385 CDS YP_001730332.1 170081012 6058118 complement(1485092..1486042) 1 NC_010473.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1486042 uspE 6058118 uspE Escherichia coli str. K-12 substr. DH10B universal stress protein UspE YP_001730332.1 1485092 R 316385 CDS YP_001730333.1 170081013 6058119 complement(1486194..1486946) 1 NC_010473.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1486946 fnr 6058119 fnr Escherichia coli str. K-12 substr. DH10B fumarate/nitrate reduction transcriptional regulator YP_001730333.1 1486194 R 316385 CDS YP_001730334.1 170081014 6058117 complement(1487141..1487656) 1 NC_010473.1 O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1487656 ogt 6058117 ogt Escherichia coli str. K-12 substr. DH10B O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_001730334.1 1487141 R 316385 CDS YP_001730335.1 170081015 6058122 complement(1487667..1489193) 1 NC_010473.1 putative aminobenzoyl-glutamate transporter 1489193 abgT 6058122 abgT Escherichia coli str. K-12 substr. DH10B putative aminobenzoyl-glutamate transporter YP_001730335.1 1487667 R 316385 CDS YP_001730336.1 170081016 6058139 complement(1489230..1490675) 1 NC_010473.1 peptidase, aminobenzoyl-glutamate utilization protein 1490675 abgB 6058139 abgB Escherichia coli str. K-12 substr. DH10B peptidase, aminobenzoyl-glutamate utilization protein YP_001730336.1 1489230 R 316385 CDS YP_001730337.1 170081017 6058134 complement(1490675..1491985) 1 NC_010473.1 peptidase, aminobenzoyl-glutamate utilization protein 1491985 abgA 6058134 abgA Escherichia coli str. K-12 substr. DH10B peptidase, aminobenzoyl-glutamate utilization protein YP_001730337.1 1490675 R 316385 CDS YP_001730338.1 170081018 6058111 1492161..1493069 1 NC_010473.1 putative DNA-binding transcriptional regulator 1493069 abgR 6058111 abgR Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001730338.1 1492161 D 316385 CDS YP_001730339.1 170081019 6062214 1493399..1493962 1 NC_010473.1 hypothetical protein 1493962 ydaL 6062214 ydaL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730339.1 1493399 D 316385 CDS YP_001730340.1 170081020 6058107 complement(1493983..1495215) 1 NC_010473.1 diguanylate cyclase domain-containing signalling protein 1495215 ydaM 6058107 ydaM Escherichia coli str. K-12 substr. DH10B diguanylate cyclase domain-containing signalling protein YP_001730340.1 1493983 R 316385 CDS YP_001730341.1 170081021 6058109 1495470..1496453 1 NC_010473.1 zinc transporter 1496453 zntB 6058109 zntB Escherichia coli str. K-12 substr. DH10B zinc transporter YP_001730341.1 1495470 D 316385 CDS YP_001730342.1 170081022 6058115 1496931..1498304 1 NC_010473.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1498304 dbpA 6058115 dbpA Escherichia coli str. K-12 substr. DH10B ATP-dependent RNA helicase DbpA YP_001730342.1 1496931 D 316385 CDS YP_001730343.1 170081023 6058106 complement(1498433..1499368) 1 NC_010473.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1499368 ttcA 6058106 ttcA Escherichia coli str. K-12 substr. DH10B C32 tRNA thiolase YP_001730343.1 1498433 R 316385 CDS YP_001730344.1 170081024 6058100 complement(1499420..1500655) 1 NC_010473.1 contains a synonymous change in codon 113; Rac prophage integrase 1500655 intR 6058100 intR Escherichia coli str. K-12 substr. DH10B Rac prophage integrase YP_001730344.1 1499420 R 316385 CDS YP_001730345.1 170081025 6058103 complement(1500657..1500872) 1 NC_010473.1 Rac prophage; protein 1500872 ydaQ 6058103 ydaQ Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730345.1 1500657 R 316385 CDS YP_001730346.1 170081026 6058096 complement(1500951..1501160) 1 NC_010473.1 Rac prophage; hypothetical protein 1501160 ydaC 6058096 ydaC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730346.1 1500951 R 316385 CDS YP_001730347.1 170081027 6058093 complement(1501153..1501347) 1 NC_010473.1 seems to be involved in restriction alleviation and enhancement of modification by EcoKI, but not in restriction alleviation of type III restriction systems; Rac prophage; restriction alleviation and modification protein 1501347 lar 6058093 lar Escherichia coli str. K-12 substr. DH10B restriction alleviation and modification protein YP_001730347.1 1501153 R 316385 CDS YP_001730348.1 170081028 6058094 complement(1501404..1502213) 1 NC_010473.1 recombination and repair protein RecT 1502213 recT 6058094 recT Escherichia coli str. K-12 substr. DH10B recombination and repair protein RecT YP_001730348.1 1501404 R 316385 CDS YP_001730349.1 170081029 6058092 complement(1502206..1504806) 1 NC_010473.1 The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB, recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA, RecF, RecJ, RecO, RecR, and RuvC.; exonuclease VIII 1504806 recE 6058092 recE Escherichia coli str. K-12 substr. DH10B exonuclease VIII YP_001730349.1 1502206 R 316385 CDS YP_001730350.1 170081030 6058095 complement(1504908..1505183) 1 NC_010473.1 Rac prophage hypothetical protein; hypothetical protein 1505183 racC 6058095 racC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730350.1 1504908 R 316385 CDS YP_001730351.1 170081031 6058086 complement(1505258..1505428) 1 NC_010473.1 Rac prophage; protein 1505428 ydaE 6058086 ydaE Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730351.1 1505258 R 316385 CDS YP_001730352.1 170081032 6058087 complement(1505428..1505649) 1 NC_010473.1 Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division; FtsZ inhibitor protein 1505649 kil 6058087 kil Escherichia coli str. K-12 substr. DH10B FtsZ inhibitor protein YP_001730352.1 1505428 R 316385 CDS YP_001730353.1 170081033 6058085 1506091..1506579 1 NC_010473.1 Rac prophage; phage superinfection exclusion protein 1506579 sieB 6058085 sieB Escherichia coli str. K-12 substr. DH10B Rac prophage; phage superinfection exclusion protein YP_001730353.1 1506091 D 316385 CDS YP_001730354.1 170081034 6058088 complement(1506576..1506731) 1 NC_010473.1 Rac prophage; protein 1506731 ydaF 6058088 ydaF Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730354.1 1506576 R 316385 CDS YP_001730355.1 170081035 6058104 complement(1506742..1506876) 1 NC_010473.1 Rac prophage; protein 1506876 ydaG 6058104 ydaG Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730355.1 1506742 R 316385 CDS YP_001730356.1 170081036 6058097 complement(1507185..1507661) 1 NC_010473.1 Rac prophage; DNA-binding transcriptional regulator 1507661 racR 6058097 racR Escherichia coli str. K-12 substr. DH10B Rac prophage; DNA-binding transcriptional regulator YP_001730356.1 1507185 R 316385 CDS YP_001730357.1 170081037 6058081 1507785..1508081 1 NC_010473.1 Rac prophage; DNA-binding transcriptional regulator 1508081 ydaS 6058081 ydaS Escherichia coli str. K-12 substr. DH10B Rac prophage; DNA-binding transcriptional regulator YP_001730357.1 1507785 D 316385 CDS YP_001730358.1 170081038 6058082 1508104..1508526 1 NC_010473.1 Rac prophage; protein 1508526 ydaT 6058082 ydaT Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730358.1 1508104 D 316385 CDS YP_001730359.1 170081039 6058079 1508539..1509396 1 NC_010473.1 Rac prophage; protein 1509396 ydaU 6058079 ydaU Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730359.1 1508539 D 316385 CDS YP_001730360.1 170081040 6058080 1509403..1510149 1 NC_010473.1 putative replication protein 1510149 ydaV 6058080 ydaV Escherichia coli str. K-12 substr. DH10B putative replication protein YP_001730360.1 1509403 D 316385 CDS YP_001730361.1 170081041 6058083 1510172..1510732 1 NC_010473.1 Rac prophage; DNA-binding protein 1510732 ydaW 6058083 ydaW Escherichia coli str. K-12 substr. DH10B Rac prophage; DNA-binding protein YP_001730361.1 1510172 D 316385 CDS YP_001730362.1 170081042 6058078 1510765..1511064 1 NC_010473.1 Rac prophage; defective peptidase 1511064 rzpR 6058078 rzpR Escherichia coli str. K-12 substr. DH10B Rac prophage; defective peptidase YP_001730362.1 1510765 D 316385 CDS YP_001730363.1 170081043 6058365 1510820..1511005 1 NC_010473.1 Rac prophage; lipoprotein 1511005 rzoR 6058365 rzoR Escherichia coli str. K-12 substr. DH10B Rac prophage; lipoprotein YP_001730363.1 1510820 D 316385 CDS YP_001730364.1 170081044 6058076 1511202..1512659 1 NC_010473.1 Rac prophage; potassium transporter subunit 1512659 trkG 6058076 trkG Escherichia coli str. K-12 substr. DH10B Rac prophage; potassium transporter subunit YP_001730364.1 1511202 D 316385 CDS YP_001730365.1 170081045 6058101 1512797..1513060 1 NC_010473.1 Rac prophage; protein 1513060 ynaK 6058101 ynaK Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730365.1 1512797 D 316385 CDS YP_001730366.1 170081046 6058531 1513041..1513400 1 NC_010473.1 Rac prophage; protein 1513400 ydaY 6058531 ydaY Escherichia coli str. K-12 substr. DH10B Rac prophage; protein YP_001730366.1 1513041 D 316385 CDS YP_001730367.1 170081047 6058452 1513874..1514902 1 NC_010473.1 Rac prophage; tail protein 1514902 ynaA 6058452 ynaA Escherichia coli str. K-12 substr. DH10B Rac prophage; tail protein YP_001730367.1 1513874 D 316385 CDS YP_001730368.1 170081048 6058629 complement(1515166..1516146) 1 NC_010473.1 contains the nonsynonymous change E214K; IS5 transposase and trans-activator 1516146 insH-5 6058629 insH-5 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001730368.1 1515166 R 316385 CDS YP_001730369.1 170081049 6058450 1516469..1519831 1 NC_010473.1 Rac prophage; tail fiber protein 1519831 stfR 6058450 stfR Escherichia coli str. K-12 substr. DH10B Rac prophage; tail fiber protein YP_001730369.1 1516469 D 316385 CDS YP_001730370.1 170081050 6062420 1519831..1520406 1 NC_010473.1 Rac prophage; tail fiber assembly protein 1520406 tfaR 6062420 tfaR Escherichia coli str. K-12 substr. DH10B Rac prophage; tail fiber assembly protein YP_001730370.1 1519831 D 316385 CDS YP_001730371.1 170081051 6062379 complement(1520504..1521094) 1 NC_010473.1 Rac prophage; site-specific recombinase 1521094 pinR 6062379 pinR Escherichia coli str. K-12 substr. DH10B Rac prophage; site-specific recombinase YP_001730371.1 1520504 R 316385 CDS YP_001730372.1 170081052 6062412 complement(1521411..1521677) 1 NC_010473.1 Rac prophage; DNA-binding transcriptional regulator 1521677 ynaE 6062412 ynaE Escherichia coli str. K-12 substr. DH10B Rac prophage; DNA-binding transcriptional regulator YP_001730372.1 1521411 R 316385 CDS YP_001730373.1 170081053 6062376 complement(1523804..1524238) 1 NC_010473.1 stress-induced protein, ATP-binding protein 1524238 uspF 6062376 uspF Escherichia coli str. K-12 substr. DH10B stress-induced protein, ATP-binding protein YP_001730373.1 1523804 R 316385 CDS YP_001730374.1 170081054 6058077 complement(1524379..1525512) 1 NC_010473.1 outer membrane pore protein N, non-specific 1525512 ompN 6058077 ompN Escherichia coli str. K-12 substr. DH10B outer membrane pore protein N, non-specific YP_001730374.1 1524379 R 316385 CDS YP_001730375.1 170081055 6058837 complement(1525879..1529403) 1 NC_010473.1 fused pyruvate-flavodoxin oxidoreductase: FeS binding protein 1529403 ydbK 6058837 ydbK Escherichia coli str. K-12 substr. DH10B fused pyruvate-flavodoxin oxidoreductase: FeS binding protein YP_001730375.1 1525879 R 316385 CDS YP_001730376.1 170081056 6062423 1529677..1529943 1 NC_010473.1 hypothetical protein 1529943 ydbJ 6062423 ydbJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730376.1 1529677 D 316385 CDS YP_001730377.1 170081057 6058772 complement(1529940..1530362) 1 NC_010473.1 heat-inducible protein 1530362 hslJ 6058772 hslJ Escherichia coli str. K-12 substr. DH10B heat-inducible protein YP_001730377.1 1529940 R 316385 CDS YP_001730378.1 170081058 6062427 complement(1530473..1531462) 1 NC_010473.1 fermentative D-lactate dehydrogenase, NAD-dependent 1531462 ldhA 6062427 ldhA Escherichia coli str. K-12 substr. DH10B fermentative D-lactate dehydrogenase, NAD-dependent YP_001730378.1 1530473 R 316385 CDS YP_001730379.1 170081059 6059693 1531670..1534309 1 NC_010473.1 hypothetical protein 1534309 ydbH 6059693 ydbH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730379.1 1531670 D 316385 CDS YP_001730380.1 170081060 6060452 1534306..1534491 1 NC_010473.1 lipoprotein 1534491 ynbE 6060452 ynbE Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730380.1 1534306 D 316385 CDS YP_001730381.1 170081061 6062369 1534499..1534825 1 NC_010473.1 hypothetical protein 1534825 ydbL 6062369 ydbL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730381.1 1534499 D 316385 CDS YP_001730382.1 170081062 6059416 complement(1534997..1535902) 1 NC_010473.1 activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR 1535902 feaR 6059416 feaR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator FeaR YP_001730382.1 1534997 R 316385 CDS YP_001730383.1 170081063 6059371 1536138..1537637 1 NC_010473.1 phenylacetaldehyde dehydrogenase 1537637 feaB 6059371 feaB Escherichia coli str. K-12 substr. DH10B phenylacetaldehyde dehydrogenase YP_001730383.1 1536138 D 316385 CDS YP_001730384.1 170081064 6059061 complement(1537695..1539968) 1 NC_010473.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 1539968 tynA 6059061 tynA Escherichia coli str. K-12 substr. DH10B tyramine oxidase YP_001730384.1 1537695 R 316385 CDS YP_001730385.1 170081065 6059814 complement(1540216..1542261) 1 NC_010473.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 1542261 maoC 6059814 maoC Escherichia coli str. K-12 substr. DH10B bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase YP_001730385.1 1540216 R 316385 CDS YP_001730386.1 170081066 6059072 1542546..1543475 1 NC_010473.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 1543475 paaA 6059072 paaA Escherichia coli str. K-12 substr. DH10B phenylacetate-CoA oxygenase subunit PaaA YP_001730386.1 1542546 D 316385 CDS YP_001730387.1 170081067 6062404 1543487..1543774 1 NC_010473.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 1543774 paaB 6062404 paaB Escherichia coli str. K-12 substr. DH10B phenylacetate-CoA oxygenase subunit PaaB YP_001730387.1 1543487 D 316385 CDS YP_001730388.1 170081068 6062418 1543783..1544529 1 NC_010473.1 multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1544529 paaC 6062418 paaC Escherichia coli str. K-12 substr. DH10B multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_001730388.1 1543783 D 316385 CDS YP_001730389.1 170081069 6062387 1544544..1545041 1 NC_010473.1 multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1545041 paaD 6062387 paaD Escherichia coli str. K-12 substr. DH10B multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_001730389.1 1544544 D 316385 CDS YP_001730390.1 170081070 6060395 1545049..1546119 1 NC_010473.1 multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1546119 paaE 6060395 paaE Escherichia coli str. K-12 substr. DH10B multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_001730390.1 1545049 D 316385 CDS YP_001730391.1 170081071 6060202 1546116..1546883 1 NC_010473.1 enoyl-CoA hydratase-isomerase 1546883 paaF 6060202 paaF Escherichia coli str. K-12 substr. DH10B enoyl-CoA hydratase-isomerase YP_001730391.1 1546116 D 316385 CDS YP_001730392.1 170081072 6062430 1546883..1547671 1 NC_010473.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1547671 paaG 6062430 paaG Escherichia coli str. K-12 substr. DH10B enoyl-CoA hydratase YP_001730392.1 1546883 D 316385 CDS YP_001730393.1 170081073 6062366 1547673..1549100 1 NC_010473.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1549100 paaH 6062366 paaH Escherichia coli str. K-12 substr. DH10B 3-hydroxyacyl-CoA dehydrogenase YP_001730393.1 1547673 D 316385 CDS YP_001730394.1 170081074 6058888 1549090..1549512 1 NC_010473.1 thioesterase 1549512 paaI 6058888 paaI Escherichia coli str. K-12 substr. DH10B thioesterase YP_001730394.1 1549090 D 316385 CDS YP_001730395.1 170081075 6058877 1549512..1550717 1 NC_010473.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 1550717 paaJ 6058877 paaJ Escherichia coli str. K-12 substr. DH10B beta-ketoadipyl CoA thiolase YP_001730395.1 1549512 D 316385 CDS YP_001730396.1 170081076 6059795 1550744..1552057 1 NC_010473.1 phenylacetyl-CoA ligase 1552057 paaK 6059795 paaK Escherichia coli str. K-12 substr. DH10B phenylacetyl-CoA ligase YP_001730396.1 1550744 D 316385 CDS YP_001730397.1 170081077 6058929 1552158..1553108 1 NC_010473.1 DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive 1553108 paaX 6058929 paaX Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive YP_001730397.1 1552158 D 316385 CDS YP_001730398.1 170081078 6060171 1553090..1553680 1 NC_010473.1 hexapeptide repeat-containing acetyltransferase 1553680 paaY 6060171 paaY Escherichia coli str. K-12 substr. DH10B hexapeptide repeat-containing acetyltransferase YP_001730398.1 1553090 D 316385 CDS YP_001730399.1 170081079 6058675 complement(1556540..1557445) 1 NC_010473.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 1557445 insD-2 6058675 insD-2 Escherichia coli str. K-12 substr. DH10B insertion element IS2 transposase InsD YP_001730399.1 1556540 R 316385 CDS YP_001730400.1 170081080 6059743 complement(1557403..1557813) 1 NC_010473.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 1557813 insC-2 6059743 insC-2 Escherichia coli str. K-12 substr. DH10B insertion sequence 2 OrfA protein YP_001730400.1 1557403 R 316385 CDS YP_001730401.1 170081081 6059182 1557977..1559128 1 NC_010473.1 contains two mutations: a synonymous change in codon 231, and the nonsynonymous change L261V; IS30 transposase 1559128 insI-2 6059182 insI-2 Escherichia coli str. K-12 substr. DH10B IS30 transposase YP_001730401.1 1557977 D 316385 CDS YP_001730402.1 170081082 6058634 1562840..1563700 1 NC_010473.1 putative oxidoreductase 1563700 ydbC 6058634 ydbC Escherichia coli str. K-12 substr. DH10B putative oxidoreductase YP_001730402.1 1562840 D 316385 CDS YP_001730403.1 170081083 6059602 1563763..1566069 1 NC_010473.1 hypothetical protein 1566069 ydbD 6059602 ydbD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730403.1 1563763 D 316385 CDS YP_001730404.1 170081084 6059604 1566240..1566845 1 NC_010473.1 inner membrane protein 1566845 ynbA 6059604 ynbA Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730404.1 1566240 D 316385 CDS YP_001730405.1 170081085 6058779 1566845..1567741 1 NC_010473.1 CDP-diglyceride synthase 1567741 ynbB 6058779 ynbB Escherichia coli str. K-12 substr. DH10B CDP-diglyceride synthase YP_001730405.1 1566845 D 316385 CDS YP_001730406.1 170081086 6060139 1567757..1569514 1 NC_010473.1 hydrolase 1569514 ynbC 6060139 ynbC Escherichia coli str. K-12 substr. DH10B hydrolase YP_001730406.1 1567757 D 316385 CDS YP_001730407.1 170081087 6062309 1569528..1570820 1 NC_010473.1 phosphatase, inner membrane protein 1570820 ynbD 6062309 ynbD Escherichia coli str. K-12 substr. DH10B phosphatase, inner membrane protein YP_001730407.1 1569528 D 316385 CDS YP_001730408.1 170081088 6058519 complement(1570874..1571479) 1 NC_010473.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1571479 azoR 6058519 azoR Escherichia coli str. K-12 substr. DH10B azoreductase YP_001730408.1 1570874 R 316385 CDS YP_001730409.1 170081089 6058664 1571680..1575582 1 NC_010473.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1575582 hrpA 6058664 hrpA Escherichia coli str. K-12 substr. DH10B ATP-dependent RNA helicase HrpA YP_001730409.1 1571680 D 316385 CDS YP_001730410.1 170081090 6058176 1575854..1576654 1 NC_010473.1 hypothetical protein 1576654 ydcF 6058176 ydcF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730410.1 1575854 D 316385 CDS YP_001730411.1 170081091 6058212 1576851..1578290 1 NC_010473.1 NAD-linked; aldehyde dehydrogenase A 1578290 aldA 6058212 aldA Escherichia coli str. K-12 substr. DH10B aldehyde dehydrogenase A YP_001730411.1 1576851 D 316385 CDS YP_001730412.1 170081092 6058682 1579521..1580051 1 NC_010473.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1580051 cybB 6058682 cybB Escherichia coli str. K-12 substr. DH10B cytochrome b561 YP_001730412.1 1579521 D 316385 CDS YP_001730413.1 170081093 6060469 1580296..1580469 1 NC_010473.1 hypothetical protein 1580469 ydcA 6060469 ydcA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730413.1 1580296 D 316385 CDS YP_001730414.1 170081094 6058870 complement(1580541..1580690) 1 NC_010473.1 small toxic polypeptide 1580690 hokB 6058870 hokB Escherichia coli str. K-12 substr. DH10B small toxic polypeptide YP_001730414.1 1580541 R 316385 CDS YP_001730415.1 170081095 6062350 complement(1580581..1580748) 1 NC_010473.1 regulatory peptide 1580748 mokB 6062350 mokB Escherichia coli str. K-12 substr. DH10B regulatory peptide YP_001730415.1 1580581 R 316385 CDS YP_001730416.1 170081096 6061063 1581089..1582729 1 NC_010473.1 methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1582729 trg 6061063 trg Escherichia coli str. K-12 substr. DH10B methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor YP_001730416.1 1581089 D 316385 CDS YP_001730417.1 170081097 6061383 complement(1582767..1583690) 1 NC_010473.1 DNA-binding transcriptional regulator 1583690 ydcI 6061383 ydcI Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730417.1 1582767 R 316385 CDS YP_001730418.1 170081098 6062070 1583907..1585250 1 NC_010473.1 hypothetical protein 1585250 ydcJ 6062070 ydcJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730418.1 1583907 D 316385 CDS YP_001730419.1 170081099 6060410 1585475..1587130 1 NC_010473.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1587130 mdoD 6060410 mdoD Escherichia coli str. K-12 substr. DH10B glucan biosynthesis protein D YP_001730419.1 1585475 D 316385 CDS YP_001730420.1 170081100 6058348 1587270..1587494 1 NC_010473.1 hypothetical protein 1587494 ydcH 6058348 ydcH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730420.1 1587270 D 316385 CDS YP_001730421.1 170081101 6059329 1587557..1588096 1 NC_010473.1 ribosomal-protein-L7/L12-serine acetyltransferase 1588096 rimL 6059329 rimL Escherichia coli str. K-12 substr. DH10B ribosomal-protein-L7/L12-serine acetyltransferase YP_001730421.1 1587557 D 316385 CDS YP_001730422.1 170081102 6061108 complement(1588088..1589068) 1 NC_010473.1 hypothetical protein 1589068 ydcK 6061108 ydcK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730422.1 1588088 R 316385 CDS YP_001730423.1 170081103 6062349 1589192..1590184 1 NC_010473.1 potassium-tellurite ethidium and proflavin transporter 1590184 tehA 6062349 tehA Escherichia coli str. K-12 substr. DH10B potassium-tellurite ethidium and proflavin transporter YP_001730423.1 1589192 D 316385 CDS YP_001730424.1 170081104 6058278 1590181..1590774 1 NC_010473.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1590774 tehB 6058278 tehB Escherichia coli str. K-12 substr. DH10B tellurite resistance protein TehB YP_001730424.1 1590181 D 316385 CDS YP_001730425.1 170081105 6058466 1591076..1591744 1 NC_010473.1 lipoprotein 1591744 ydcL 6058466 ydcL Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730425.1 1591076 D 316385 CDS YP_001730426.1 170081106 6058722 1592276..1593484 1 NC_010473.1 transposase 1593484 ydcM 6058722 ydcM Escherichia coli str. K-12 substr. DH10B transposase YP_001730426.1 1592276 D 316385 CDS YP_001730427.1 170081107 6060111 complement(1593524..1594699) 1 NC_010473.1 benzoate transporter 1594699 ydcO 6060111 ydcO Escherichia coli str. K-12 substr. DH10B benzoate transporter YP_001730427.1 1593524 R 316385 CDS YP_001730428.1 170081108 6058252 1594791..1595327 1 NC_010473.1 DNA-binding transcriptional regulator 1595327 ydcN 6058252 ydcN Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730428.1 1594791 D 316385 CDS YP_001730429.1 170081109 6058257 1595400..1597361 1 NC_010473.1 peptidase 1597361 ydcP 6058257 ydcP Escherichia coli str. K-12 substr. DH10B peptidase YP_001730429.1 1595400 D 316385 CDS YP_001730430.1 170081110 6058090 complement(1597453..1597683) 1 NC_010473.1 hypothetical protein 1597683 yncJ 6058090 yncJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730430.1 1597453 R 316385 CDS YP_001730431.1 170081111 6058354 1597905..1598081 1 NC_010473.1 hypothetical protein 1598081 yncN 6058354 yncN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730431.1 1597905 D 316385 CDS YP_001730432.1 170081112 6061141 1598106..1598543 1 NC_010473.1 DNA-binding transcriptional regulator 1598543 ydcQ 6061141 ydcQ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730432.1 1598106 D 316385 CDS YP_001730433.1 170081113 6058145 1598622..1600028 1 NC_010473.1 fused DNA-binding transcriptional regulator; amino transferase 1600028 ydcR 6058145 ydcR Escherichia coli str. K-12 substr. DH10B fused DNA-binding transcriptional regulator; amino transferase YP_001730433.1 1598622 D 316385 CDS YP_001730434.1 170081114 6058773 1600273..1601418 1 NC_010473.1 spermidine/putrescine ABC transporter periplasmic-binding protein 1601418 ydcS 6058773 ydcS Escherichia coli str. K-12 substr. DH10B spermidine/putrescine ABC transporter periplasmic-binding protein YP_001730434.1 1600273 D 316385 CDS YP_001730435.1 170081115 6058453 1601436..1602449 1 NC_010473.1 spermidine/putrescine ABC transporter ATP-binding protein 1602449 ydcT 6058453 ydcT Escherichia coli str. K-12 substr. DH10B spermidine/putrescine ABC transporter ATP-binding protein YP_001730435.1 1601436 D 316385 CDS YP_001730436.1 170081116 6058387 1602450..1603391 1 NC_010473.1 spermidine/putrescine ABC transporter membrane protein 1603391 ydcU 6058387 ydcU Escherichia coli str. K-12 substr. DH10B spermidine/putrescine ABC transporter membrane protein YP_001730436.1 1602450 D 316385 CDS YP_001730437.1 170081117 6058435 1603381..1604175 1 NC_010473.1 spermidine/putrescine ABC transporter membrane protein 1604175 ydcV 6058435 ydcV Escherichia coli str. K-12 substr. DH10B spermidine/putrescine ABC transporter membrane protein YP_001730437.1 1603381 D 316385 CDS YP_001730438.1 170081118 6059746 1604197..1605621 1 NC_010473.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1605621 ydcW 6059746 ydcW Escherichia coli str. K-12 substr. DH10B gamma-aminobutyraldehyde dehydrogenase YP_001730438.1 1604197 D 316385 CDS YP_001730439.1 170081119 6062377 1606008..1606181 1 NC_010473.1 inner membrane protein 1606181 ydcX 6062377 ydcX Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730439.1 1606008 D 316385 CDS YP_001730440.1 170081120 6058527 1606267..1606500 1 NC_010473.1 hypothetical protein 1606500 ydcY 6058527 ydcY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730440.1 1606267 D 316385 CDS YP_001730441.1 170081121 6058284 complement(1606501..1606950) 1 NC_010473.1 inner membrane protein 1606950 ydcZ 6058284 ydcZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730441.1 1606501 R 316385 CDS YP_001730442.1 170081122 6059479 complement(1606947..1607465) 1 NC_010473.1 acyltransferase 1607465 yncA 6059479 yncA Escherichia coli str. K-12 substr. DH10B acyltransferase YP_001730442.1 1606947 R 316385 CDS YP_001730443.1 170081123 6062331 1607646..1608683 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 1608683 yncB 6062331 yncB Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001730443.1 1607646 D 316385 CDS YP_001730444.1 170081124 6062347 1608881..1609546 1 NC_010473.1 putative DNA-binding transcriptional regulator 1609546 yncC 6062347 yncC Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001730444.1 1608881 D 316385 CDS YP_001730445.1 170081125 6062253 complement(1609582..1611684) 1 NC_010473.1 iron outer membrane transporter 1611684 yncD 6062253 yncD Escherichia coli str. K-12 substr. DH10B iron outer membrane transporter YP_001730445.1 1609582 R 316385 CDS YP_001730446.1 170081126 6062405 1611926..1612987 1 NC_010473.1 hypothetical protein 1612987 yncE 6062405 yncE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730446.1 1611926 D 316385 CDS YP_001730447.1 170081127 6062132 complement(1613100..1614599) 1 NC_010473.1 L-asparagine transporter 1614599 ansP 6062132 ansP Escherichia coli str. K-12 substr. DH10B L-asparagine transporter YP_001730447.1 1613100 R 316385 CDS YP_001730448.1 170081128 6058133 1614866..1615483 1 NC_010473.1 hypothetical protein 1615483 yncG 6058133 yncG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730448.1 1614866 D 316385 CDS YP_001730449.1 170081129 6058434 1615559..1615771 1 NC_010473.1 hypothetical protein 1615771 yncH 6058434 yncH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730449.1 1615559 D 316385 CDS YP_001730450.1 170081130 6058732 1618541..1619023 1 NC_010473.1 hypothetical protein 1619023 ydcD 6058732 ydcD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730450.1 1618541 D 316385 CDS YP_001730451.1 170081131 6058797 1620435..1621571 1 NC_010473.1 hypothetical protein 1621571 ydcC 6058797 ydcC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730451.1 1620435 D 316385 CDS YP_001730452.1 170081132 6060737 1621671..1621904 1 NC_010473.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1621904 pptA 6060737 pptA Escherichia coli str. K-12 substr. DH10B 4-oxalocrotonate tautomerase YP_001730452.1 1621671 D 316385 CDS YP_001730453.1 170081133 6060426 complement(1621901..1622470) 1 NC_010473.1 hypothetical protein 1622470 yddH 6060426 yddH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730453.1 1621901 R 316385 CDS YP_001730454.1 170081134 6058438 1622643..1623488 1 NC_010473.1 N-hydroxyarylamine O-acetyltransferase 1623488 nhoA 6058438 nhoA Escherichia coli str. K-12 substr. DH10B N-hydroxyarylamine O-acetyltransferase YP_001730454.1 1622643 D 316385 CDS YP_001730455.1 170081135 6058221 complement(1623584..1624477) 1 NC_010473.1 hypothetical protein 1624477 yddE 6058221 yddE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730455.1 1623584 R 316385 CDS YP_001730456.1 170081136 6058597 complement(1624556..1625236) 1 NC_010473.1 nitrate reductase 2 (NRZ), gamma subunit 1625236 narV 6058597 narV Escherichia coli str. K-12 substr. DH10B nitrate reductase 2 (NRZ), gamma subunit YP_001730456.1 1624556 R 316385 CDS YP_001730457.1 170081137 6058474 complement(1625233..1625928) 1 NC_010473.1 nitrate reductase 2 (NRZ), delta subunit (assembly subunit) 1625928 narW 6058474 narW Escherichia coli str. K-12 substr. DH10B nitrate reductase 2 (NRZ), delta subunit (assembly subunit) YP_001730457.1 1625233 R 316385 CDS YP_001730458.1 170081138 6058317 complement(1625928..1627472) 1 NC_010473.1 nitrate reductase 2 (NRZ), beta subunit 1627472 narY 6058317 narY Escherichia coli str. K-12 substr. DH10B nitrate reductase 2 (NRZ), beta subunit YP_001730458.1 1625928 R 316385 CDS YP_001730459.1 170081139 6058229 complement(1627469..1631209) 1 NC_010473.1 nitrate reductase 2 (NRZ), alpha subunit 1631209 narZ 6058229 narZ Escherichia coli str. K-12 substr. DH10B nitrate reductase 2 (NRZ), alpha subunit YP_001730459.1 1627469 R 316385 CDS YP_001730460.1 170081140 6062264 complement(1631291..1632679) 1 NC_010473.1 nitrate/nitrite transporter 1632679 narU 6062264 narU Escherichia coli str. K-12 substr. DH10B nitrate/nitrite transporter YP_001730460.1 1631291 R 316385 CDS YP_001730461.1 170081141 6058596 complement(1633003..1633338) 1 NC_010473.1 hypothetical protein 1633338 yddJ 6058596 yddJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730461.1 1633003 R 316385 CDS YP_001730462.1 170081142 6062304 complement(1633377..1634333) 1 NC_010473.1 hypothetical protein 1634333 yddK 6062304 yddK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730462.1 1633377 R 316385 CDS YP_001730463.1 170081143 6062209 complement(1634357..1634647) 1 NC_010473.1 lipoprotein 1634647 yddL 6062209 yddL Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730463.1 1634357 R 316385 CDS YP_001730464.1 170081144 6062375 complement(1634907..1635788) 1 NC_010473.1 hypothetical protein 1635788 yddG 6062375 yddG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730464.1 1634907 R 316385 CDS YP_001730465.1 170081145 6062270 1636020..1639067 1 NC_010473.1 formate dehydrogenase-N subunit alpha, nitrate-inducible 1639067 fdnG 6062270 fdnG Escherichia coli str. K-12 substr. DH10B formate dehydrogenase-N subunit alpha, nitrate-inducible YP_001730465.1 1636020 D 316385 CDS YP_001730466.1 170081146 6062344 1639080..1639964 1 NC_010473.1 formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible 1639964 fdnH 6062344 fdnH Escherichia coli str. K-12 substr. DH10B formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible YP_001730466.1 1639080 D 316385 CDS YP_001730467.1 170081147 6062240 1639957..1640610 1 NC_010473.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1640610 fdnI 6062240 fdnI Escherichia coli str. K-12 substr. DH10B formate dehydrogenase-N subunit gamma YP_001730467.1 1639957 D 316385 CDS YP_001730468.1 170081148 6062275 complement(1641017..1641301) 1 NC_010473.1 DNA-binding transcriptional regulator 1641301 yddM 6062275 yddM Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730468.1 1641017 R 316385 CDS YP_001730469.1 170081149 6062183 complement(1641447..1642457) 1 NC_010473.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1642457 adhP 6062183 adhP Escherichia coli str. K-12 substr. DH10B alcohol dehydrogenase YP_001730469.1 1641447 R 316385 CDS YP_001730470.1 170081150 6062279 complement(1642591..1644288) 1 NC_010473.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1644288 maeA 6062279 maeA Escherichia coli str. K-12 substr. DH10B malate dehydrogenase YP_001730470.1 1642591 R 316385 CDS YP_001730471.1 170081151 6058222 complement(1644445..1644582) 1 NC_010473.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1644582 rpsV 6058222 rpsV Escherichia coli str. K-12 substr. DH10B 30S ribosomal subunit S22 YP_001730471.1 1644445 R 316385 CDS YP_001730472.1 170081152 6062340 complement(1644684..1644899) 1 NC_010473.1 biofilm-dependent modulation protein 1644899 bdm 6062340 bdm Escherichia coli str. K-12 substr. DH10B biofilm-dependent modulation protein YP_001730472.1 1644684 R 316385 CDS YP_001730473.1 170081153 6062028 1645244..1645675 1 NC_010473.1 osmotically inducible, stress-inducible membrane protein 1645675 osmC 6062028 osmC Escherichia coli str. K-12 substr. DH10B osmotically inducible, stress-inducible membrane protein YP_001730473.1 1645244 D 316385 CDS YP_001730474.1 170081154 6062114 complement(1645731..1646657) 1 NC_010473.1 D-alanine-D-alanine ABC transporter ATP-binding protein 1646657 ddpF 6062114 ddpF Escherichia coli str. K-12 substr. DH10B D-alanine-D-alanine ABC transporter ATP-binding protein YP_001730474.1 1645731 R 316385 CDS YP_001730475.1 170081155 6061939 complement(1646650..1647636) 1 NC_010473.1 D-alanine-D-alanine ABC transporter ATP-binding protein 1647636 ddpD 6061939 ddpD Escherichia coli str. K-12 substr. DH10B D-alanine-D-alanine ABC transporter ATP-binding protein YP_001730475.1 1646650 R 316385 CDS YP_001730476.1 170081156 6062020 complement(1647633..1648529) 1 NC_010473.1 ATP-dependent peptide transporter membrane subunit 1648529 ddpC 6062020 ddpC Escherichia coli str. K-12 substr. DH10B ATP-dependent peptide transporter membrane subunit YP_001730476.1 1647633 R 316385 CDS YP_001730477.1 170081157 6062174 complement(1648526..1649548) 1 NC_010473.1 D-alanine-D-alanine ABC transporter membrane protein 1649548 ddpB 6062174 ddpB Escherichia coli str. K-12 substr. DH10B D-alanine-D-alanine ABC transporter membrane protein YP_001730477.1 1648526 R 316385 CDS YP_001730478.1 170081158 6061876 complement(1649550..1651100) 1 NC_010473.1 D-alanine-D-alanine ABC transporter periplasmic-binding protein 1651100 ddpA 6061876 ddpA Escherichia coli str. K-12 substr. DH10B D-alanine-D-alanine ABC transporter periplasmic-binding protein YP_001730478.1 1649550 R 316385 CDS YP_001730479.1 170081159 6061631 complement(1651114..1651695) 1 NC_010473.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 1651695 ddpX 6061631 ddpX Escherichia coli str. K-12 substr. DH10B D-alanyl-D-alanine dipeptidase YP_001730479.1 1651114 R 316385 CDS YP_001730480.1 170081160 6061724 complement(1651953..1654352) 1 NC_010473.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1654352 dos 6061724 dos Escherichia coli str. K-12 substr. DH10B cAMP phosphodiesterase YP_001730480.1 1651953 R 316385 CDS YP_001730481.1 170081161 6061329 complement(1654377..1655759) 1 NC_010473.1 diguanylate cyclase 1655759 yddV 6061329 yddV Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001730481.1 1654377 R 316385 CDS YP_001730482.1 170081162 6060513 complement(1656123..1657442) 1 NC_010473.1 liprotein 1657442 yddW 6060513 yddW Escherichia coli str. K-12 substr. DH10B liprotein YP_001730482.1 1656123 R 316385 CDS YP_001730483.1 170081163 6060508 complement(1657573..1659108) 1 NC_010473.1 glutamate:gamma-aminobutyric acid antiporter 1659108 gadC 6060508 gadC Escherichia coli str. K-12 substr. DH10B glutamate:gamma-aminobutyric acid antiporter YP_001730483.1 1657573 R 316385 CDS YP_001730484.1 170081164 6062180 complement(1659264..1660664) 1 NC_010473.1 glutamate decarboxylase 1660664 gadB 6062180 gadB Escherichia coli str. K-12 substr. DH10B glutamate decarboxylase YP_001730484.1 1659264 R 316385 CDS YP_001730485.1 170081165 6061220 complement(1661026..1663821) 1 NC_010473.1 peptidase 1663821 pqqL 6061220 pqqL Escherichia coli str. K-12 substr. DH10B peptidase YP_001730485.1 1661026 R 316385 CDS YP_001730486.1 170081166 6062107 complement(1663866..1666238) 1 NC_010473.1 porin protein 1666238 yddB 6062107 yddB Escherichia coli str. K-12 substr. DH10B porin protein YP_001730486.1 1663866 R 316385 CDS YP_001730487.1 170081167 6062186 complement(1666276..1667961) 1 NC_010473.1 multidrug ABC transporter membrane protein; ATP-binding protein 1667961 yddA 6062186 yddA Escherichia coli str. K-12 substr. DH10B multidrug ABC transporter membrane protein; ATP-binding protein YP_001730487.1 1666276 R 316385 CDS YP_001730488.1 170081168 6062422 complement(1668252..1669409) 1 NC_010473.1 hypothetical protein 1669409 ydeM 6062422 ydeM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730488.1 1668252 R 316385 CDS YP_001730489.1 170081169 6061053 complement(1669461..1671143) 1 NC_010473.1 hypothetical protein 1671143 ydeN 6061053 ydeN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730489.1 1669461 R 316385 CDS YP_001730490.1 170081170 6061835 complement(1671545..1672306) 1 NC_010473.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1672306 ydeO 6061835 ydeO Escherichia coli str. K-12 substr. DH10B transcriptional regulator YdeO YP_001730490.1 1671545 R 316385 CDS YP_001730491.1 170081171 6061567 complement(1672826..1675105) 1 NC_010473.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase 1675105 ydeP 6061567 ydeP Escherichia coli str. K-12 substr. DH10B putative oxidoreductase YP_001730491.1 1672826 R 316385 CDS YP_001730492.1 170081172 6062118 complement(1675439..1676353) 1 NC_010473.1 fimbrial-like adhesin protein 1676353 ydeQ 6062118 ydeQ Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001730492.1 1675439 R 316385 CDS YP_001730493.1 170081173 6062116 complement(1676412..1676915) 1 NC_010473.1 fimbrial-like adhesin protein 1676915 ydeR 6062116 ydeR Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001730493.1 1676412 R 316385 CDS YP_001730494.1 170081174 6062201 complement(1678006..1678185) 1 NC_010473.1 transcriptional regulator 1678185 yneL 6062201 yneL Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001730494.1 1678006 R 316385 CDS YP_001730495.1 170081175 6062163 complement(1678503..1679825) 1 NC_010473.1 regulator with hipB 1679825 hipA 6062163 hipA Escherichia coli str. K-12 substr. DH10B regulator with hipB YP_001730495.1 1678503 R 316385 CDS YP_001730496.1 170081176 6061012 complement(1679825..1680091) 1 NC_010473.1 DNA-binding transcriptional regulator HipB 1680091 hipB 6061012 hipB Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator HipB YP_001730496.1 1679825 R 316385 CDS YP_001730497.1 170081177 6062203 complement(1680314..1681714) 1 NC_010473.1 hypothetical protein 1681714 ydeU 6062203 ydeU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730497.1 1680314 R 316385 CDS YP_001730498.1 170081178 6062172 complement(1681758..1685735) 1 NC_010473.1 putative lipoprotein 1685735 ydeK 6062172 ydeK Escherichia coli str. K-12 substr. DH10B putative lipoprotein YP_001730498.1 1681758 R 316385 CDS YP_001730499.1 170081179 6060598 complement(1686266..1687858) 1 NC_010473.1 autoinducer-2 (AI-2) kinase 1687858 lsrK 6060598 lsrK Escherichia coli str. K-12 substr. DH10B autoinducer-2 (AI-2) kinase YP_001730499.1 1686266 R 316385 CDS YP_001730500.1 170081180 6062136 complement(1687937..1688890) 1 NC_010473.1 lsr operon transcriptional repressor 1688890 lsrR 6062136 lsrR Escherichia coli str. K-12 substr. DH10B lsr operon transcriptional repressor YP_001730500.1 1687937 R 316385 CDS YP_001730501.1 170081181 6061189 1689139..1690674 1 NC_010473.1 AI2 ABC transporter ATP-binding protein 1690674 lsrA 6061189 lsrA Escherichia coli str. K-12 substr. DH10B AI2 ABC transporter ATP-binding protein YP_001730501.1 1689139 D 316385 CDS YP_001730502.1 170081182 6062077 1690668..1691696 1 NC_010473.1 AI2 ABC transporter membrane protein 1691696 lsrC 6062077 lsrC Escherichia coli str. K-12 substr. DH10B AI2 ABC transporter membrane protein YP_001730502.1 1690668 D 316385 CDS YP_001730503.1 170081183 6061146 1691696..1692688 1 NC_010473.1 AI2 ABC transporter membrane protein 1692688 lsrD 6061146 lsrD Escherichia coli str. K-12 substr. DH10B AI2 ABC transporter membrane protein YP_001730503.1 1691696 D 316385 CDS YP_001730504.1 170081184 6061184 1692700..1693722 1 NC_010473.1 AI2 ABC transporter periplasmic-binding protein 1693722 lsrB 6061184 lsrB Escherichia coli str. K-12 substr. DH10B AI2 ABC transporter periplasmic-binding protein YP_001730504.1 1692700 D 316385 CDS YP_001730505.1 170081185 6062049 1693749..1694624 1 NC_010473.1 aldolase 1694624 lsrF 6062049 lsrF Escherichia coli str. K-12 substr. DH10B aldolase YP_001730505.1 1693749 D 316385 CDS YP_001730506.1 170081186 6062083 1694648..1694938 1 NC_010473.1 autoinducer-2 (AI-2) modifying protein LsrG 1694938 lsrG 6062083 lsrG Escherichia coli str. K-12 substr. DH10B autoinducer-2 (AI-2) modifying protein LsrG YP_001730506.1 1694648 D 316385 CDS YP_001730507.1 170081187 6061200 1694995..1695753 1 NC_010473.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1695753 tam 6061200 tam Escherichia coli str. K-12 substr. DH10B trans-aconitate 2-methyltransferase YP_001730507.1 1694995 D 316385 CDS YP_001730508.1 170081188 6061192 complement(1695757..1696671) 1 NC_010473.1 inner membrane protein 1696671 yneE 6061192 yneE Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730508.1 1695757 R 316385 CDS YP_001730509.1 170081189 6062131 complement(1698556..1699503) 1 NC_010473.1 diguanylate cyclase 1699503 yneF 6062131 yneF Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001730509.1 1698556 R 316385 CDS YP_001730510.1 170081190 6062173 complement(1699615..1699974) 1 NC_010473.1 hypothetical protein 1699974 yneG 6062173 yneG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730510.1 1699615 R 316385 CDS YP_001730511.1 170081191 6062225 complement(1699974..1700900) 1 NC_010473.1 catalyzes the formation of glutamate from glutamine; glutaminase 1700900 yneH 6062225 yneH Escherichia coli str. K-12 substr. DH10B glutaminase YP_001730511.1 1699974 R 316385 CDS YP_001730512.1 170081192 6061065 complement(1700964..1702352) 1 NC_010473.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate-semialdehyde dehydrogenase 1702352 yneI 6061065 yneI Escherichia coli str. K-12 substr. DH10B putative succinate-semialdehyde dehydrogenase YP_001730512.1 1700964 R 316385 CDS YP_001730513.1 170081193 6061208 1702453..1703334 1 NC_010473.1 DNA-binding transcriptional regulator 1703334 yneJ 6061208 yneJ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730513.1 1702453 D 316385 CDS YP_001730514.1 170081194 6062227 1703412..1704527 1 NC_010473.1 hypothetical protein 1704527 yneK 6062227 yneK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730514.1 1703412 D 316385 CDS YP_001730515.1 170081195 6061118 1704677..1705867 1 NC_010473.1 sugar efflux transporter 1705867 ydeA 6061118 ydeA Escherichia coli str. K-12 substr. DH10B sugar efflux transporter YP_001730515.1 1704677 D 316385 CDS YP_001730516.1 170081196 6060681 complement(1705892..1706557) 1 NC_010473.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1706557 marC 6060681 marC Escherichia coli str. K-12 substr. DH10B multiple drug resistance protein MarC YP_001730516.1 1705892 R 316385 CDS YP_001730517.1 170081197 6061210 1706769..1707203 1 NC_010473.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1707203 marR 6061210 marR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor MarR YP_001730517.1 1706769 D 316385 CDS YP_001730518.1 170081198 6060688 1707223..1707606 1 NC_010473.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1707606 marA 6060688 marA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator MarA YP_001730518.1 1707223 D 316385 CDS YP_001730519.1 170081199 6062207 1707638..1707856 1 NC_010473.1 hypothetical protein 1707856 marB 6062207 marB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730519.1 1707638 D 316385 CDS YP_001730520.1 170081200 6061227 complement(1707887..1708786) 1 NC_010473.1 O-acetylserine/cysteine export protein 1708786 eamA 6061227 eamA Escherichia coli str. K-12 substr. DH10B O-acetylserine/cysteine export protein YP_001730520.1 1707887 R 316385 CDS YP_001730521.1 170081201 6061181 1708981..1710168 1 NC_010473.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE 1710168 ydeE 6061181 ydeE Escherichia coli str. K-12 substr. DH10B putative MFS-type transporter YdeE YP_001730521.1 1708981 D 316385 CDS YP_001730522.1 170081202 6061187 complement(1710609..1711499) 1 NC_010473.1 hypothetical protein 1711499 ydeH 6061187 ydeH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730522.1 1710609 R 316385 CDS YP_001730523.1 170081203 6062243 complement(1711754..1712146) 1 NC_010473.1 hypothetical protein 1712146 ydeI 6062243 ydeI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730523.1 1711754 R 316385 CDS YP_001730524.1 170081204 6061253 1712422..1712940 1 NC_010473.1 competence damage-inducible protein A 1712940 ydeJ 6061253 ydeJ Escherichia coli str. K-12 substr. DH10B competence damage-inducible protein A YP_001730524.1 1712422 D 316385 CDS YP_001730525.1 170081205 6062221 complement(1712984..1715029) 1 NC_010473.1 dipeptidyl carboxypeptidase II 1715029 dcp 6062221 dcp Escherichia coli str. K-12 substr. DH10B dipeptidyl carboxypeptidase II YP_001730525.1 1712984 R 316385 CDS YP_001730526.1 170081206 6061259 1715166..1715912 1 NC_010473.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1715912 ydfG 6061259 ydfG Escherichia coli str. K-12 substr. DH10B 3-hydroxy acid dehydrogenase YP_001730526.1 1715166 D 316385 CDS YP_001730527.1 170081207 6061244 1716001..1716687 1 NC_010473.1 DNA-binding transcriptional regulator 1716687 ydfH 6061244 ydfH Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730527.1 1716001 D 316385 CDS YP_001730528.1 170081208 6060682 1716864..1717067 1 NC_010473.1 hypothetical protein 1717067 ydfZ 6060682 ydfZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730528.1 1716864 D 316385 CDS YP_001730529.1 170081209 6061033 complement(1717102..1718562) 1 NC_010473.1 mannonate dehydrogenase 1718562 ydfI 6061033 ydfI Escherichia coli str. K-12 substr. DH10B mannonate dehydrogenase YP_001730529.1 1717102 R 316385 CDS YP_001730530.1 170081210 6060704 complement(1718651..1719934) 1 NC_010473.1 transporter 1719934 ydfJ 6060704 ydfJ Escherichia coli str. K-12 substr. DH10B transporter YP_001730530.1 1718651 R 316385 CDS YP_001730531.1 170081211 6061268 1720688..1720954 1 NC_010473.1 Qin prophage; DNA-binding transcriptional regulator 1720954 ydfK 6061268 ydfK Escherichia coli str. K-12 substr. DH10B Qin prophage; DNA-binding transcriptional regulator YP_001730531.1 1720688 D 316385 CDS YP_001730532.1 170081212 6061272 1721271..1721861 1 NC_010473.1 Qin prophage; site-specific recombinase 1721861 pinQ 6061272 pinQ Escherichia coli str. K-12 substr. DH10B Qin prophage; site-specific recombinase YP_001730532.1 1721271 D 316385 CDS YP_001730533.1 170081213 6060709 complement(1721959..1722534) 1 NC_010473.1 Qin prophage; tail fiber assembly protein 1722534 tfaQ 6060709 tfaQ Escherichia coli str. K-12 substr. DH10B Qin prophage; tail fiber assembly protein YP_001730533.1 1721959 R 316385 CDS YP_001730534.1 170081214 6061214 complement(1722534..1723496) 1 NC_010473.1 Qin prophage; side tail fiber assembly protein 1723496 stfQ 6061214 stfQ Escherichia coli str. K-12 substr. DH10B Qin prophage; side tail fiber assembly protein YP_001730534.1 1722534 R 316385 CDS YP_001730535.1 170081215 6061234 complement(1723447..1724016) 1 NC_010473.1 Qin prophage; packaging protein 1724016 nohA 6061234 nohA Escherichia coli str. K-12 substr. DH10B Qin prophage; packaging protein YP_001730535.1 1723447 R 316385 CDS YP_001730536.1 170081216 6060716 1724405..1724638 1 NC_010473.1 Qin prophage; protein 1724638 ynfO 6060716 ynfO Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730536.1 1724405 D 316385 CDS YP_001730537.1 170081217 6061247 1724696..1725106 1 NC_010473.1 Qin prophage; protein 1725106 ydfO 6061247 ydfO Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730537.1 1724696 D 316385 CDS YP_001730538.1 170081218 6061310 complement(1725258..1725431) 1 NC_010473.1 Qin prophage; protein 1725431 gnsB 6061310 gnsB Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730538.1 1725258 R 316385 CDS YP_001730539.1 170081219 6060722 complement(1725603..1725758) 1 NC_010473.1 Qin prophage; protein 1725758 ynfN 6060722 ynfN Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730539.1 1725603 R 316385 CDS YP_001730540.1 170081220 6062212 complement(1726104..1726316) 1 NC_010473.1 Qin prophage; cold shock protein 1726316 cspI 6062212 cspI Escherichia coli str. K-12 substr. DH10B Qin prophage; cold shock protein YP_001730540.1 1726104 R 316385 CDS YP_001730541.1 170081221 6060725 complement(1726679..1727176) 1 NC_010473.1 Qin prophage; protein 1727176 ydfP 6060725 ydfP Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730541.1 1726679 R 316385 CDS YP_001730542.1 170081222 6061318 complement(1727173..1727706) 1 NC_010473.1 Qin prophage; lysozyme 1727706 ydfQ 6061318 ydfQ Escherichia coli str. K-12 substr. DH10B Qin prophage; lysozyme YP_001730542.1 1727173 R 316385 CDS YP_001730543.1 170081223 6061345 complement(1727703..1728014) 1 NC_010473.1 Qin prophage; protein 1728014 ydfR 6061345 ydfR Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730543.1 1727703 R 316385 CDS YP_001730544.1 170081224 6062246 complement(1728019..1728234) 1 NC_010473.1 Qin prophage; S lysis protein 1728234 essQ 6062246 essQ Escherichia coli str. K-12 substr. DH10B Qin prophage; S lysis protein YP_001730544.1 1728019 R 316385 CDS YP_001730545.1 170081225 6061348 complement(1728988..1729203) 1 NC_010473.1 Qin prophage; cold shock protein 1729203 cspB 6061348 cspB Escherichia coli str. K-12 substr. DH10B Qin prophage; cold shock protein YP_001730545.1 1728988 R 316385 CDS YP_001730546.1 170081226 6062283 1729504..1729716 1 NC_010473.1 Qin prophage; cold shock protein 1729716 cspF 6062283 cspF Escherichia coli str. K-12 substr. DH10B Qin prophage; cold shock protein YP_001730546.1 1729504 D 316385 CDS YP_001730547.1 170081227 6060566 complement(1730138..1730890) 1 NC_010473.1 Qin prophage; antitermination protein Q 1730890 ydfT 6060566 ydfT Escherichia coli str. K-12 substr. DH10B Qin prophage; antitermination protein Q YP_001730547.1 1730138 R 316385 CDS YP_001730548.1 170081228 6061292 complement(1732300..1732551) 1 NC_010473.1 Qin prophage; protein 1732551 rem 6061292 rem Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730548.1 1732300 R 316385 CDS YP_001730549.1 170081229 6061309 complement(1732768..1732923) 1 NC_010473.1 Qin prophage; small toxic polypeptide 1732923 hokD 6061309 hokD Escherichia coli str. K-12 substr. DH10B Qin prophage; small toxic polypeptide YP_001730549.1 1732768 R 316385 CDS YP_001730550.1 170081230 6062222 complement(1732995..1733282) 1 NC_010473.1 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system 1733282 relE 6062222 relE Escherichia coli str. K-12 substr. DH10B Qin prophage; toxin of the RelE-RelB toxin-antitoxin system YP_001730550.1 1732995 R 316385 CDS YP_001730551.1 170081231 6059869 complement(1733282..1733521) 1 NC_010473.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB 1733521 relB 6059869 relB Escherichia coli str. K-12 substr. DH10B bifunctional antitoxin/transcriptional repressor RelB YP_001730551.1 1733282 R 316385 CDS YP_001730552.1 170081232 6062351 1733546..1733851 1 NC_010473.1 Qin prophage; protein 1733851 ydfV 6062351 ydfV Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730552.1 1733546 D 316385 CDS YP_001730553.1 170081233 6059345 1734054..1734386 1 NC_010473.1 Qin prophage; protein 1734386 flxA 6059345 flxA Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730553.1 1734054 D 316385 CDS YP_001730554.1 170081234 6061354 complement(1734823..1734972) 1 NC_010473.1 Qin prophage; protein 1734972 ydfW 6061354 ydfW Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730554.1 1734823 R 316385 CDS YP_001730555.1 170081235 6062373 complement(1734995..1735285) 1 NC_010473.1 Qin prophage; protein 1735285 ydfX 6062373 ydfX Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730555.1 1734995 R 316385 CDS YP_001730556.1 170081236 6062401 complement(1735269..1735499) 1 NC_010473.1 DNA-binding transcriptional regulator DicC 1735499 dicC 6062401 dicC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator DicC YP_001730556.1 1735269 R 316385 CDS YP_001730557.1 170081237 6062402 1735583..1735990 1 NC_010473.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1735990 dicA 6062402 dicA Escherichia coli str. K-12 substr. DH10B transcriptional repressor DicA YP_001730557.1 1735583 D 316385 CDS YP_001730558.1 170081238 6062378 1736157..1736312 1 NC_010473.1 Qin prophage; protein 1736312 ydfA 6062378 ydfA Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730558.1 1736157 D 316385 CDS YP_001730559.1 170081239 6062358 1736314..1736442 1 NC_010473.1 Qin prophage; protein 1736442 ydfB 6062358 ydfB Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730559.1 1736314 D 316385 CDS YP_001730560.1 170081240 6062355 1736472..1736690 1 NC_010473.1 Qin prophage; protein 1736690 ydfC 6062355 ydfC Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730560.1 1736472 D 316385 CDS YP_001730561.1 170081241 6060569 1737258..1737446 1 NC_010473.1 Qin prophage; cell division inhibition protein 1737446 dicB 6060569 dicB Escherichia coli str. K-12 substr. DH10B Qin prophage; cell division inhibition protein YP_001730561.1 1737258 D 316385 CDS YP_001730562.1 170081242 6062363 1737443..1737634 1 NC_010473.1 Qin prophage; protein 1737634 ydfD 6062363 ydfD Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730562.1 1737443 D 316385 CDS YP_001730563.1 170081243 6062330 1737727..1738647 1 NC_010473.1 Qin prophage; protein 1738647 ydfE 6062330 ydfE Escherichia coli str. K-12 substr. DH10B Qin prophage; protein YP_001730563.1 1737727 D 316385 CDS YP_001730564.1 170081244 6062320 complement(1741881..1742900) 1 NC_010473.1 putative dehydrogenase 1742900 rspB 6062320 rspB Escherichia coli str. K-12 substr. DH10B putative dehydrogenase YP_001730564.1 1741881 R 316385 CDS YP_001730565.1 170081245 6062360 complement(1742912..1744126) 1 NC_010473.1 dehydratase 1744126 rspA 6062360 rspA Escherichia coli str. K-12 substr. DH10B dehydratase YP_001730565.1 1742912 R 316385 CDS YP_001730566.1 170081246 6062223 complement(1744332..1744658) 1 NC_010473.1 hypothetical protein 1744658 ynfA 6062223 ynfA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730566.1 1744332 R 316385 CDS YP_001730567.1 170081247 6062371 1744793..1745134 1 NC_010473.1 hypothetical protein 1745134 ynfB 6062371 ynfB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730567.1 1744793 D 316385 CDS YP_001730568.1 170081248 6062365 1745169..1745729 1 NC_010473.1 spermidine N1-acetyltransferase 1745729 speG 6062365 speG Escherichia coli str. K-12 substr. DH10B spermidine N1-acetyltransferase YP_001730568.1 1745169 D 316385 CDS YP_001730569.1 170081249 6062381 complement(1745732..1746442) 1 NC_010473.1 hypothetical protein 1746442 ynfC 6062381 ynfC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730569.1 1745732 R 316385 CDS YP_001730570.1 170081250 6062303 1746550..1746855 1 NC_010473.1 hypothetical protein 1746855 ynfD 6062303 ynfD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730570.1 1746550 D 316385 CDS YP_001730571.1 170081251 6062296 1747054..1749480 1 NC_010473.1 oxidoreductase subunit 1749480 ynfE 6062296 ynfE Escherichia coli str. K-12 substr. DH10B oxidoreductase subunit YP_001730571.1 1747054 D 316385 CDS YP_001730572.1 170081252 6062337 1749541..1751964 1 NC_010473.1 oxidoreductase subunit 1751964 ynfF 6062337 ynfF Escherichia coli str. K-12 substr. DH10B oxidoreductase subunit YP_001730572.1 1749541 D 316385 CDS YP_001730573.1 170081253 6062267 1751975..1752592 1 NC_010473.1 oxidoreductase, Fe-S subunit 1752592 ynfG 6062267 ynfG Escherichia coli str. K-12 substr. DH10B oxidoreductase, Fe-S subunit YP_001730573.1 1751975 D 316385 CDS YP_001730574.1 170081254 6062252 1752594..1753448 1 NC_010473.1 oxidoreductase, membrane subunit 1753448 ynfH 6062252 ynfH Escherichia coli str. K-12 substr. DH10B oxidoreductase, membrane subunit YP_001730574.1 1752594 D 316385 CDS YP_001730575.1 170081255 6062318 1753491..1754105 1 NC_010473.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1754105 dmsD 6062318 dmsD Escherichia coli str. K-12 substr. DH10B twin-argninine leader-binding protein DmsD YP_001730575.1 1753491 D 316385 CDS YP_001730576.1 170081256 6058655 1754300..1755556 1 NC_010473.1 putative voltage-gated ClC-type chloride channel ClcB 1755556 clcB 6058655 clcB Escherichia coli str. K-12 substr. DH10B putative voltage-gated ClC-type chloride channel ClcB YP_001730576.1 1754300 D 316385 CDS YP_001730577.1 170081257 6058911 complement(1755509..1756204) 1 NC_010473.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase 1756204 ynfK 6058911 ynfK Escherichia coli str. K-12 substr. DH10B putative dithiobiotin synthetase YP_001730577.1 1755509 R 316385 CDS YP_001730578.1 170081258 6059088 complement(1756329..1757549) 1 NC_010473.1 DNA-binding transcriptional repressor 1757549 dgsA 6059088 dgsA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor YP_001730578.1 1756329 R 316385 CDS YP_001730579.1 170081259 6058974 complement(1757684..1758577) 1 NC_010473.1 DNA-binding transcriptional regulator 1758577 ynfL 6058974 ynfL Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730579.1 1757684 R 316385 CDS YP_001730580.1 170081260 6059570 1758684..1759937 1 NC_010473.1 transporter 1759937 ynfM 6059570 ynfM Escherichia coli str. K-12 substr. DH10B transporter YP_001730580.1 1758684 D 316385 CDS YP_001730581.1 170081261 6060319 1760361..1760669 1 NC_010473.1 required for growth and survival under moderately acid conditions; acid shock protein 1760669 asr 6060319 asr Escherichia coli str. K-12 substr. DH10B acid shock protein YP_001730581.1 1760361 D 316385 CDS YP_001730582.1 170081262 6060397 1760945..1761766 1 NC_010473.1 peptidase 1761766 ydgD 6060397 ydgD Escherichia coli str. K-12 substr. DH10B peptidase YP_001730582.1 1760945 D 316385 CDS YP_001730583.1 170081263 6059262 complement(1761805..1762134) 1 NC_010473.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1762134 mdtI 6059262 mdtI Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein MdtI YP_001730583.1 1761805 R 316385 CDS YP_001730584.1 170081264 6059237 complement(1762121..1762486) 1 NC_010473.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 1762486 mdtJ 6059237 mdtJ Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein MdtJ YP_001730584.1 1762121 R 316385 CDS YP_001730585.1 170081265 6059165 1762898..1763932 1 NC_010473.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein 1763932 tqsA 6059165 tqsA Escherichia coli str. K-12 substr. DH10B putative transport protein YP_001730585.1 1762898 D 316385 CDS YP_001730586.1 170081266 6059009 complement(1763957..1765345) 1 NC_010473.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1765345 pntB 6059009 pntB Escherichia coli str. K-12 substr. DH10B pyridine nucleotide transhydrogenase YP_001730586.1 1763957 R 316385 CDS YP_001730587.1 170081267 6058971 complement(1765356..1766888) 1 NC_010473.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1766888 pntA 6058971 pntA Escherichia coli str. K-12 substr. DH10B NAD(P) transhydrogenase subunit alpha YP_001730587.1 1765356 R 316385 CDS YP_001730588.1 170081268 6058690 1767412..1768356 1 NC_010473.1 hypothetical protein 1768356 ydgH 6058690 ydgH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730588.1 1767412 D 316385 CDS YP_001730589.1 170081269 6058681 1768542..1769924 1 NC_010473.1 arginine/ornithine transporter 1769924 ydgI 6058681 ydgI Escherichia coli str. K-12 substr. DH10B arginine/ornithine transporter YP_001730589.1 1768542 D 316385 CDS YP_001730590.1 170081270 6059380 1769961..1770683 1 NC_010473.1 short chain dehydrogenase 1770683 folM 6059380 folM Escherichia coli str. K-12 substr. DH10B short chain dehydrogenase YP_001730590.1 1769961 D 316385 CDS YP_001730591.1 170081271 6059789 complement(1770680..1771015) 1 NC_010473.1 inner membrane protein associated with alginate biosynthesis 1771015 ydgC 6059789 ydgC Escherichia coli str. K-12 substr. DH10B inner membrane protein associated with alginate biosynthesis YP_001730591.1 1770680 R 316385 CDS YP_001730592.1 170081272 6059238 1771135..1771863 1 NC_010473.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1771863 rstA 6059238 rstA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator RstA YP_001730592.1 1771135 D 316385 CDS YP_001730593.1 170081273 6059453 1771867..1773168 1 NC_010473.1 sensor protein RstB 1773168 rstB 6059453 rstB Escherichia coli str. K-12 substr. DH10B sensor protein RstB YP_001730593.1 1771867 D 316385 CDS YP_001730594.1 170081274 6060496 1773244..1774173 1 NC_010473.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1774173 tus 6060496 tus Escherichia coli str. K-12 substr. DH10B DNA replication terminus site-binding protein YP_001730594.1 1773244 D 316385 CDS YP_001730595.1 170081275 6059759 complement(1774170..1775573) 1 NC_010473.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1775573 fumC 6059759 fumC Escherichia coli str. K-12 substr. DH10B fumarate hydratase YP_001730595.1 1774170 R 316385 CDS YP_001730596.1 170081276 6059791 complement(1775716..1777362) 1 NC_010473.1 fumarate hydratase, aerobic class I 1777362 fumA 6059791 fumA Escherichia coli str. K-12 substr. DH10B fumarate hydratase, aerobic class I YP_001730596.1 1775716 R 316385 CDS YP_001730597.1 170081277 6059901 1777561..1778736 1 NC_010473.1 mannose-6-phosphate isomerase 1778736 manA 6059901 manA Escherichia coli str. K-12 substr. DH10B mannose-6-phosphate isomerase YP_001730597.1 1777561 D 316385 CDS YP_001730598.1 170081278 6061860 1778837..1780345 1 NC_010473.1 hypothetical protein 1780345 ydgA 6061860 ydgA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730598.1 1778837 D 316385 CDS YP_001730599.1 170081279 6061886 complement(1780571..1781836) 1 NC_010473.1 putative outer membrane porin protein 1781836 uidC 6061886 uidC Escherichia coli str. K-12 substr. DH10B putative outer membrane porin protein YP_001730599.1 1780571 R 316385 CDS YP_001730600.1 170081280 6061776 complement(1781875..1783248) 1 NC_010473.1 glucuronide transporter 1783248 uidB 6061776 uidB Escherichia coli str. K-12 substr. DH10B glucuronide transporter YP_001730600.1 1781875 R 316385 CDS YP_001730601.1 170081281 6061790 complement(1783245..1785056) 1 NC_010473.1 beta-D-glucuronidase 1785056 uidA 6061790 uidA Escherichia coli str. K-12 substr. DH10B beta-D-glucuronidase YP_001730601.1 1783245 R 316385 CDS YP_001730602.1 170081282 6061806 complement(1785447..1786037) 1 NC_010473.1 DNA-binding transcriptional repressor 1786037 uidR 6061806 uidR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor YP_001730602.1 1785447 R 316385 CDS YP_001730603.1 170081283 6061820 complement(1786258..1787025) 1 NC_010473.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1787025 hdhA 6061820 hdhA Escherichia coli str. K-12 substr. DH10B 7-alpha-hydroxysteroid dehydrogenase YP_001730603.1 1786258 R 316385 CDS YP_001730604.1 170081284 6061821 complement(1787137..1788165) 1 NC_010473.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1788165 malI 6061821 malI Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor MalI YP_001730604.1 1787137 R 316385 CDS YP_001730605.1 170081285 6061823 1788340..1789932 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1789932 malX 6061823 malX Escherichia coli str. K-12 substr. DH10B bifunctional PTS system maltose and glucose-specific transporter subunits IICB YP_001730605.1 1788340 D 316385 CDS YP_001730606.1 170081286 6061827 1789942..1791114 1 NC_010473.1 bifunctional beta-cystathionase and regulator of maltose regulon 1791114 malY 6061827 malY Escherichia coli str. K-12 substr. DH10B bifunctional beta-cystathionase and regulator of maltose regulon YP_001730606.1 1789942 D 316385 CDS YP_001730607.1 170081287 6061844 1791218..1792219 1 NC_010473.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1792219 add 6061844 add Escherichia coli str. K-12 substr. DH10B adenosine deaminase YP_001730607.1 1791218 D 316385 CDS YP_001730608.1 170081288 6061854 complement(1792253..1793293) 1 NC_010473.1 putative oxidoreductase 1793293 ydgJ 6061854 ydgJ Escherichia coli str. K-12 substr. DH10B putative oxidoreductase YP_001730608.1 1792253 R 316385 CDS YP_001730609.1 170081289 6061857 1793544..1793759 1 NC_010473.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1793759 ydgT 6061857 ydgT Escherichia coli str. K-12 substr. DH10B oriC-binding nucleoid-associated protein YP_001730609.1 1793544 D 316385 CDS YP_001730610.1 170081290 6061858 1793845..1794285 1 NC_010473.1 inner membrane protein 1794285 ydgK 6061858 ydgK Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730610.1 1793845 D 316385 CDS YP_001730611.1 170081291 6061862 1794362..1794943 1 NC_010473.1 Na(+)-translocating NADH-quinone reductase subunit E 1794943 rsxA 6061862 rsxA Escherichia coli str. K-12 substr. DH10B Na(+)-translocating NADH-quinone reductase subunit E YP_001730611.1 1794362 D 316385 CDS YP_001730612.1 170081292 6061863 1794943..1795521 1 NC_010473.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1795521 rsxB 6061863 rsxB Escherichia coli str. K-12 substr. DH10B electron transport complex protein RnfB YP_001730612.1 1794943 D 316385 CDS YP_001730613.1 170081293 6061864 1795514..1797736 1 NC_010473.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1797736 rsxC 6061864 rsxC Escherichia coli str. K-12 substr. DH10B electron transport complex protein RnfC YP_001730613.1 1795514 D 316385 CDS YP_001730614.1 170081294 6061875 1797737..1798795 1 NC_010473.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1798795 rnfD 6061875 rnfD Escherichia coli str. K-12 substr. DH10B electron transport complex protein RnfD YP_001730614.1 1797737 D 316385 CDS YP_001730615.1 170081295 6061879 1798799..1799419 1 NC_010473.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1799419 rsxG 6061879 rsxG Escherichia coli str. K-12 substr. DH10B electron transport complex protein RnfG YP_001730615.1 1798799 D 316385 CDS YP_001730616.1 170081296 6061883 1799423..1800118 1 NC_010473.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1800118 rsxE 6061883 rsxE Escherichia coli str. K-12 substr. DH10B electron transport complex protein RsxE YP_001730616.1 1799423 D 316385 CDS YP_001730617.1 170081297 6061884 1800118..1800753 1 NC_010473.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1800753 nth 6061884 nth Escherichia coli str. K-12 substr. DH10B endonuclease III YP_001730617.1 1800118 D 316385 CDS YP_001730618.1 170081298 6061889 1801364..1802866 1 NC_010473.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1802866 tppB 6061889 tppB Escherichia coli str. K-12 substr. DH10B putative tripeptide transporter permease YP_001730618.1 1801364 D 316385 CDS YP_001730619.1 170081299 6061899 1802972..1803577 1 NC_010473.1 glutathionine S-transferase 1803577 gst 6061899 gst Escherichia coli str. K-12 substr. DH10B glutathionine S-transferase YP_001730619.1 1802972 D 316385 CDS YP_001730620.1 170081300 6061906 complement(1803621..1804484) 1 NC_010473.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1804484 pdxY 6061906 pdxY Escherichia coli str. K-12 substr. DH10B pyridoxamine kinase YP_001730620.1 1803621 R 316385 CDS YP_001730621.1 170081301 6061908 complement(1804543..1805817) 1 NC_010473.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1805817 tyrS 6061908 tyrS Escherichia coli str. K-12 substr. DH10B tyrosyl-tRNA synthetase YP_001730621.1 1804543 R 316385 CDS YP_001730622.1 170081302 6061926 complement(1805946..1806602) 1 NC_010473.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1806602 pdxH 6061926 pdxH Escherichia coli str. K-12 substr. DH10B pyridoxamine 5'-phosphate oxidase YP_001730622.1 1805946 R 316385 CDS YP_001730623.1 170081303 6061931 complement(1806661..1806990) 1 NC_010473.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1806990 ydhA 6061931 ydhA Escherichia coli str. K-12 substr. DH10B lysozyme inhibitor YP_001730623.1 1806661 R 316385 CDS YP_001730624.1 170081304 6061940 complement(1807088..1808197) 1 NC_010473.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1808197 anmK 6061940 anmK Escherichia coli str. K-12 substr. DH10B anhydro-N-acetylmuramic acid kinase YP_001730624.1 1807088 R 316385 CDS YP_001730625.1 170081305 6061942 1808471..1808938 1 NC_010473.1 outer membrane lipoprotein 1808938 slyB 6061942 slyB Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein YP_001730625.1 1808471 D 316385 CDS YP_001730626.1 170081306 6061949 complement(1808985..1809419) 1 NC_010473.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1809419 slyA 6061949 slyA Escherichia coli str. K-12 substr. DH10B transcriptional regulator SlyA YP_001730626.1 1808985 R 316385 CDS YP_001730627.1 170081307 6061954 1809859..1810716 1 NC_010473.1 undecaprenyl pyrophosphate phosphatase 1810716 ydhJ 6061954 ydhJ Escherichia coli str. K-12 substr. DH10B undecaprenyl pyrophosphate phosphatase YP_001730627.1 1809859 D 316385 CDS YP_001730628.1 170081308 6061965 1810716..1812728 1 NC_010473.1 inner membrane protein 1812728 ydhK 6061965 ydhK Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730628.1 1810716 D 316385 CDS YP_001730629.1 170081309 6061966 complement(1812729..1813250) 1 NC_010473.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1813250 sodC 6061966 sodC Escherichia coli str. K-12 substr. DH10B superoxide dismutase YP_001730629.1 1812729 R 316385 CDS YP_001730630.1 170081310 6061967 complement(1813331..1814227) 1 NC_010473.1 oxidoreductase 1814227 ydhF 6061967 ydhF Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001730630.1 1813331 R 316385 CDS YP_001730631.1 170081311 6061988 complement(1814276..1814515) 1 NC_010473.1 hypothetical protein 1814515 ydhL 6061988 ydhL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730631.1 1814276 R 316385 CDS YP_001730632.1 170081312 6061992 1814702..1815217 1 NC_010473.1 DNA-binding transcriptional regulator 1815217 ydhM 6061992 ydhM Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730632.1 1814702 D 316385 CDS YP_001730633.1 170081313 6061996 1815254..1816351 1 NC_010473.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1816351 nemA 6061996 nemA Escherichia coli str. K-12 substr. DH10B N-ethylmaleimide reductase YP_001730633.1 1815254 D 316385 CDS YP_001730634.1 170081314 6062001 1816432..1816839 1 NC_010473.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1816839 gloA 6062001 gloA Escherichia coli str. K-12 substr. DH10B glyoxalase I YP_001730634.1 1816432 D 316385 CDS YP_001730635.1 170081315 6062002 1816942..1817589 1 NC_010473.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1817589 rnt 6062002 rnt Escherichia coli str. K-12 substr. DH10B ribonuclease T YP_001730635.1 1816942 D 316385 CDS YP_001730636.1 170081316 6062015 1817682..1822298 1 NC_010473.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr 1822298 lhr 6062015 lhr Escherichia coli str. K-12 substr. DH10B putative ATP-dependent helicase Lhr YP_001730636.1 1817682 D 316385 CDS YP_001730637.1 170081317 6062018 complement(1822349..1822696) 1 NC_010473.1 hypothetical protein 1822696 grxD 6062018 grxD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730637.1 1822349 R 316385 CDS YP_001730638.1 170081318 6062022 1823030..1823845 1 NC_010473.1 lipoprotein 1823845 ydhO 6062022 ydhO Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730638.1 1823030 D 316385 CDS YP_001730639.1 170081319 6062033 1823973..1824554 1 NC_010473.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1824554 sodB 6062033 sodB Escherichia coli str. K-12 substr. DH10B superoxide dismutase YP_001730639.1 1823973 D 316385 CDS YP_001730640.1 170081320 6062038 complement(1824716..1825885) 1 NC_010473.1 transporter 1825885 ydhP 6062038 ydhP Escherichia coli str. K-12 substr. DH10B transporter YP_001730640.1 1824716 R 316385 CDS YP_001730641.1 170081321 6062056 complement(1827461..1828393) 1 NC_010473.1 putative DNA-binding transcriptional regulator 1828393 ydhB 6062056 ydhB Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001730641.1 1827461 R 316385 CDS YP_001730642.1 170081322 6062066 1828506..1829717 1 NC_010473.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1829717 ydhC 6062066 ydhC Escherichia coli str. K-12 substr. DH10B inner membrane transport protein YdhC YP_001730642.1 1828506 D 316385 CDS YP_001730643.1 170081323 6062082 1830008..1831156 1 NC_010473.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1831156 cfa 6062082 cfa Escherichia coli str. K-12 substr. DH10B cyclopropane-fatty-acyl-phospholipid synthase YP_001730643.1 1830008 D 316385 CDS YP_001730644.1 170081324 6062086 complement(1831196..1831837) 1 NC_010473.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1831837 ribC 6062086 ribC Escherichia coli str. K-12 substr. DH10B riboflavin synthase subunit alpha YP_001730644.1 1831196 R 316385 CDS YP_001730645.1 170081325 6062087 1832052..1833425 1 NC_010473.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1833425 mdtK 6062087 mdtK Escherichia coli str. K-12 substr. DH10B multidrug efflux protein YP_001730645.1 1832052 D 316385 CDS YP_001730646.1 170081326 6062088 complement(1833466..1834722) 1 NC_010473.1 hypothetical protein 1834722 ydhQ 6062088 ydhQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730646.1 1833466 R 316385 CDS YP_001730647.1 170081327 6061680 1835295..1835600 1 NC_010473.1 hypothetical protein 1835600 ydhR 6061680 ydhR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730647.1 1835295 D 316385 CDS YP_001730648.1 170081328 6062100 1835726..1837330 1 NC_010473.1 hypothetical protein 1837330 ydhS 6062100 ydhS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730648.1 1835726 D 316385 CDS YP_001730649.1 170081329 6062104 complement(1837342..1838154) 1 NC_010473.1 hypothetical protein 1838154 ydhT 6062104 ydhT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730649.1 1837342 R 316385 CDS YP_001730650.1 170081330 6062117 complement(1838158..1838943) 1 NC_010473.1 cytochrome 1838943 ydhU 6062117 ydhU Escherichia coli str. K-12 substr. DH10B cytochrome YP_001730650.1 1838158 R 316385 CDS YP_001730651.1 170081331 6062124 complement(1838940..1839608) 1 NC_010473.1 4Fe-4S ferredoxin 1839608 ydhX 6062124 ydhX Escherichia coli str. K-12 substr. DH10B 4Fe-4S ferredoxin YP_001730651.1 1838940 R 316385 CDS YP_001730652.1 170081332 6062133 complement(1839672..1840319) 1 NC_010473.1 hypothetical protein 1840319 ydhW 6062133 ydhW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730652.1 1839672 R 316385 CDS YP_001730653.1 170081333 6062138 complement(1840323..1842425) 1 NC_010473.1 putative oxidoreductase 1842425 ydhV 6062138 ydhV Escherichia coli str. K-12 substr. DH10B putative oxidoreductase YP_001730653.1 1840323 R 316385 CDS YP_001730654.1 170081334 6062139 complement(1842446..1843072) 1 NC_010473.1 hypothetical protein 1843072 ydhY 6062139 ydhY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730654.1 1842446 R 316385 CDS YP_001730655.1 170081335 6062140 complement(1843527..1843736) 1 NC_010473.1 hypothetical protein 1843736 ydhZ 6062140 ydhZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730655.1 1843527 R 316385 CDS YP_001730656.1 170081336 6062142 1844293..1845705 1 NC_010473.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1845705 pykF 6062142 pykF Escherichia coli str. K-12 substr. DH10B pyruvate kinase YP_001730656.1 1844293 D 316385 CDS YP_001730657.1 170081337 6062143 1846016..1846252 1 NC_010473.1 murein lipoprotein 1846252 lpp 6062143 lpp Escherichia coli str. K-12 substr. DH10B murein lipoprotein YP_001730657.1 1846016 D 316385 CDS YP_001730658.1 170081338 6062149 complement(1846316..1847320) 1 NC_010473.1 hypothetical protein 1847320 ynhG 6062149 ynhG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730658.1 1846316 R 316385 CDS YP_001730659.1 170081339 6062155 complement(1847469..1847885) 1 NC_010473.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1847885 sufE 6062155 sufE Escherichia coli str. K-12 substr. DH10B cysteine desufuration protein SufE YP_001730659.1 1847469 R 316385 CDS YP_001730660.1 170081340 6062160 complement(1847898..1849118) 1 NC_010473.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1849118 sufS 6062160 sufS Escherichia coli str. K-12 substr. DH10B bifunctional cysteine desulfurase/selenocysteine lyase YP_001730660.1 1847898 R 316385 CDS YP_001730661.1 170081341 6062161 complement(1849115..1850386) 1 NC_010473.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1850386 sufD 6062161 sufD Escherichia coli str. K-12 substr. DH10B cysteine desulfurase activator complex subunit SufD YP_001730661.1 1849115 R 316385 CDS YP_001730662.1 170081342 6062162 complement(1850361..1851107) 1 NC_010473.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 1851107 sufC 6062162 sufC Escherichia coli str. K-12 substr. DH10B cysteine desulfurase YP_001730662.1 1850361 R 316385 CDS YP_001730663.1 170081343 6062166 complement(1851117..1852604) 1 NC_010473.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1852604 sufB 6062166 sufB Escherichia coli str. K-12 substr. DH10B cysteine desulfurase activator complex subunit SufB YP_001730663.1 1851117 R 316385 CDS YP_001730664.1 170081344 6062171 complement(1852613..1852981) 1 NC_010473.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1852981 sufA 6062171 sufA Escherichia coli str. K-12 substr. DH10B iron-sulfur cluster assembly scaffold protein YP_001730664.1 1852613 R 316385 CDS YP_001730665.1 170081345 6059715 complement(1853529..1853798) 1 NC_010473.1 hypothetical protein 1853798 ydiH 6059715 ydiH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730665.1 1853529 R 316385 CDS YP_001730666.1 170081346 6062178 complement(1853817..1854227) 1 NC_010473.1 hypothetical protein 1854227 ydiI 6062178 ydiI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730666.1 1853817 R 316385 CDS YP_001730667.1 170081347 6062181 complement(1854224..1857280) 1 NC_010473.1 FAD-linked oxidoreductase 1857280 ydiJ 6062181 ydiJ Escherichia coli str. K-12 substr. DH10B FAD-linked oxidoreductase YP_001730667.1 1854224 R 316385 CDS YP_001730668.1 170081348 6062182 1857669..1858781 1 NC_010473.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 1858781 ydiK 6062182 ydiK Escherichia coli str. K-12 substr. DH10B putative inner membrane protein YP_001730668.1 1857669 D 316385 CDS YP_001730669.1 170081349 6059270 1859210..1859566 1 NC_010473.1 hypothetical protein 1859566 ydiL 6059270 ydiL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730669.1 1859210 D 316385 CDS YP_001730670.1 170081350 6062190 1859666..1860880 1 NC_010473.1 transporter 1860880 ydiM 6062190 ydiM Escherichia coli str. K-12 substr. DH10B transporter YP_001730670.1 1859666 D 316385 CDS YP_001730671.1 170081351 6062192 1861107..1862372 1 NC_010473.1 transporter 1862372 ydiN 6062192 ydiN Escherichia coli str. K-12 substr. DH10B transporter YP_001730671.1 1861107 D 316385 CDS YP_001730672.1 170081352 6062193 1862384..1863250 1 NC_010473.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1863250 ydiB 6062193 ydiB Escherichia coli str. K-12 substr. DH10B quinate/shikimate dehydrogenase YP_001730672.1 1862384 D 316385 CDS YP_001730673.1 170081353 6062211 1863281..1864039 1 NC_010473.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1864039 aroD 6062211 aroD Escherichia coli str. K-12 substr. DH10B 3-dehydroquinate dehydratase YP_001730673.1 1863281 D 316385 CDS YP_001730674.1 170081354 6062216 1865791..1866942 1 NC_010473.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase 1866942 ydiO 6062216 ydiO Escherichia coli str. K-12 substr. DH10B putative acyl-CoA dehydrogenase YP_001730674.1 1865791 D 316385 CDS YP_001730675.1 170081355 6062230 complement(1866985..1867896) 1 NC_010473.1 DNA-binding transcriptional regulator 1867896 ydiP 6062230 ydiP Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730675.1 1866985 R 316385 CDS YP_001730676.1 170081356 6062239 1868212..1868976 1 NC_010473.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ 1868976 ydiQ 6062239 ydiQ Escherichia coli str. K-12 substr. DH10B putative electron transfer flavoprotein YdiQ YP_001730676.1 1868212 D 316385 CDS YP_001730677.1 170081357 6062241 1868996..1869934 1 NC_010473.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1869934 ydiR 6062241 ydiR Escherichia coli str. K-12 substr. DH10B electron transfer flavoprotein subunit YdiR YP_001730677.1 1868996 D 316385 CDS YP_001730678.1 170081358 6062257 1869990..1871279 1 NC_010473.1 hypothetical protein 1871279 ydiS 6062257 ydiS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730678.1 1869990 D 316385 CDS YP_001730679.1 170081359 6062262 1871276..1871569 1 NC_010473.1 4Fe-4S ferredoxin 1871569 ydiT 6062262 ydiT Escherichia coli str. K-12 substr. DH10B 4Fe-4S ferredoxin YP_001730679.1 1871276 D 316385 CDS YP_001730680.1 170081360 6062271 1871572..1873272 1 NC_010473.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1873272 ydiD 6062271 ydiD Escherichia coli str. K-12 substr. DH10B short chain acyl-CoA synthetase YP_001730680.1 1871572 D 316385 CDS YP_001730681.1 170081361 6062273 complement(1873329..1875707) 1 NC_010473.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1875707 pps 6062273 pps Escherichia coli str. K-12 substr. DH10B phosphoenolpyruvate synthase YP_001730681.1 1873329 R 316385 CDS YP_001730682.1 170081362 6062277 1876040..1876873 1 NC_010473.1 hypothetical protein 1876873 ydiA 6062277 ydiA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730682.1 1876040 D 316385 CDS YP_001730683.1 170081363 6062284 1877030..1878076 1 NC_010473.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1878076 aroH 6062284 aroH Escherichia coli str. K-12 substr. DH10B phospho-2-dehydro-3-deoxyheptonate aldolase YP_001730683.1 1877030 D 316385 CDS YP_001730684.1 170081364 6062287 1878208..1878399 1 NC_010473.1 hypothetical protein 1878399 ydiE 6062287 ydiE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730684.1 1878208 D 316385 CDS YP_001730685.1 170081365 6062293 complement(1878403..1879839) 1 NC_010473.1 hypothetical protein 1879839 ydiU 6062293 ydiU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730685.1 1878403 R 316385 CDS YP_001730686.1 170081366 6062298 complement(1879902..1880615) 1 NC_010473.1 hypothetical protein 1880615 ydiV 6062298 ydiV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730686.1 1879902 R 316385 CDS YP_001730687.1 170081367 6062307 complement(1880862..1881326) 1 NC_010473.1 lipoprotein 1881326 nlpC 6062307 nlpC Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730687.1 1880862 R 316385 CDS YP_001730688.1 170081368 6062322 complement(1881404..1882153) 1 NC_010473.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1882153 btuD 6062322 btuD Escherichia coli str. K-12 substr. DH10B vitamin B12-transporter ATPase YP_001730688.1 1881404 R 316385 CDS YP_001730689.1 170081369 6062364 complement(1882153..1882704) 1 NC_010473.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase 1882704 btuE 6062364 btuE Escherichia coli str. K-12 substr. DH10B putative glutathione peroxidase YP_001730689.1 1882153 R 316385 CDS YP_001730690.1 170081370 6062370 complement(1882767..1883747) 1 NC_010473.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1883747 btuC 6062370 btuC Escherichia coli str. K-12 substr. DH10B vtamin B12-transporter permease YP_001730690.1 1882767 R 316385 CDS YP_001730691.1 170081371 6062397 complement(1883848..1884147) 1 NC_010473.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1884147 ihfA 6062397 ihfA Escherichia coli str. K-12 substr. DH10B integration host factor subunit alpha YP_001730691.1 1883848 R 316385 CDS YP_001730692.1 170081372 6059612 complement(1884152..1886539) 1 NC_010473.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1886539 pheT 6059612 pheT Escherichia coli str. K-12 substr. DH10B phenylalanyl-tRNA synthetase subunit beta YP_001730692.1 1884152 R 316385 CDS YP_001730693.1 170081373 6059730 complement(1886554..1887537) 1 NC_010473.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1887537 pheS 6059730 pheS Escherichia coli str. K-12 substr. DH10B phenylalanyl-tRNA synthetase subunit alpha YP_001730693.1 1886554 R 316385 CDS YP_001730695.1 170081375 6062341 complement(1887988..1888344) 1 NC_010473.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1888344 rplT 6062341 rplT Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L20 YP_001730695.1 1887988 R 316385 CDS YP_001730696.1 170081376 6059285 complement(1888397..1888594) 1 NC_010473.1 50S ribosomal protein L35 1888594 rpmI 6059285 rpmI Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L35 YP_001730696.1 1888397 R 316385 CDS YP_001730697.1 170081377 6058835 complement(1889237..1891165) 1 NC_010473.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1891165 thrS 6058835 thrS Escherichia coli str. K-12 substr. DH10B threonyl-tRNA synthetase YP_001730697.1 1889237 R 316385 CDS YP_001730698.1 170081378 6059709 1893745..1893867 1 NC_010473.1 hypothetical protein 1893867 yniD 6059709 yniD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730698.1 1893745 D 316385 CDS YP_001730699.1 170081379 6059105 complement(1893920..1894678) 1 NC_010473.1 hypothetical protein 1894678 ydiY 6059105 ydiY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730699.1 1893920 R 316385 CDS YP_001730700.1 170081380 6059131 1894965..1895894 1 NC_010473.1 6-phosphofructokinase 1895894 pfkB 6059131 pfkB Escherichia coli str. K-12 substr. DH10B 6-phosphofructokinase YP_001730700.1 1894965 D 316385 CDS YP_001730701.1 170081381 6059718 1895995..1896285 1 NC_010473.1 hypothetical protein 1896285 ydiZ 6059718 ydiZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730701.1 1895995 D 316385 CDS YP_001730702.1 170081382 6060197 1896391..1897251 1 NC_010473.1 phosphotransferase/kinase 1897251 yniA 6060197 yniA Escherichia coli str. K-12 substr. DH10B phosphotransferase/kinase YP_001730702.1 1896391 D 316385 CDS YP_001730703.1 170081383 6058864 complement(1897292..1897828) 1 NC_010473.1 inner membrane protein 1897828 yniB 6058864 yniB Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730703.1 1897292 R 316385 CDS YP_001730704.1 170081384 6060331 1897975..1898643 1 NC_010473.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1898643 yniC 6060331 yniC Escherichia coli str. K-12 substr. DH10B 2-deoxyglucose-6-phosphatase YP_001730704.1 1897975 D 316385 CDS YP_001730705.1 170081385 6059768 1898806..1899396 1 NC_010473.1 hypothetical protein 1899396 ydjM 6059768 ydjM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730705.1 1898806 D 316385 CDS YP_001730706.1 170081386 6060162 1899529..1900920 1 NC_010473.1 transporter 1900920 ydjN 6060162 ydjN Escherichia coli str. K-12 substr. DH10B transporter YP_001730706.1 1899529 D 316385 CDS YP_001730707.1 170081387 6058710 complement(1900924..1901739) 1 NC_010473.1 hypothetical protein 1901739 ydjO 6058710 ydjO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730707.1 1900924 R 316385 CDS YP_001730708.1 170081388 6058674 complement(1902016..1902279) 1 NC_010473.1 cell division modulator 1902279 cedA 6058674 cedA Escherichia coli str. K-12 substr. DH10B cell division modulator YP_001730708.1 1902016 R 316385 CDS YP_001730709.1 170081389 6062391 1902462..1904723 1 NC_010473.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1904723 katE 6062391 katE Escherichia coli str. K-12 substr. DH10B hydroperoxidase II YP_001730709.1 1902462 D 316385 CDS YP_001730710.1 170081390 6062385 complement(1904981..1905730) 1 NC_010473.1 hypothetical protein 1905730 chbG 6062385 chbG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730710.1 1904981 R 316385 CDS YP_001730711.1 170081391 6058781 complement(1905743..1907095) 1 NC_010473.1 cryptic phospho-beta-glucosidase, NAD(P)-binding 1907095 chbF 6058781 chbF Escherichia coli str. K-12 substr. DH10B cryptic phospho-beta-glucosidase, NAD(P)-binding YP_001730711.1 1905743 R 316385 CDS YP_001730712.1 170081392 6058689 complement(1907200..1908042) 1 NC_010473.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1908042 chbR 6058689 chbR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator ChbR YP_001730712.1 1907200 R 316385 CDS YP_001730713.1 170081393 6062276 complement(1908050..1908400) 1 NC_010473.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1908400 chbA 6062276 chbA Escherichia coli str. K-12 substr. DH10B PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_001730713.1 1908050 R 316385 CDS YP_001730714.1 170081394 6059142 complement(1908451..1909809) 1 NC_010473.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1909809 chbC 6059142 chbC Escherichia coli str. K-12 substr. DH10B PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_001730714.1 1908451 R 316385 CDS YP_001730715.1 170081395 6059143 complement(1909894..1910214) 1 NC_010473.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1910214 chbB 6059143 chbB Escherichia coli str. K-12 substr. DH10B PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_001730715.1 1909894 R 316385 CDS YP_001730716.1 170081396 6059139 complement(1910513..1910851) 1 NC_010473.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1910851 osmE 6059139 osmE Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator OsmE YP_001730716.1 1910513 R 316385 CDS YP_001730717.1 170081397 6059160 1911053..1911880 1 NC_010473.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1911880 nadE 6059160 nadE Escherichia coli str. K-12 substr. DH10B NAD synthetase YP_001730717.1 1911053 D 316385 CDS YP_001730718.1 170081398 6062274 1912110..1912997 1 NC_010473.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1912997 cho 6062274 cho Escherichia coli str. K-12 substr. DH10B nucleotide excision repair endonuclease YP_001730718.1 1912110 D 316385 CDS YP_001730719.1 170081399 6062248 complement(1912957..1913532) 1 NC_010473.1 hypothetical protein 1913532 ydjR 6062248 ydjR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730719.1 1912957 R 316385 CDS YP_001730720.1 170081400 6062326 complement(1913735..1914220) 1 NC_010473.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 1914220 spy 6062326 spy Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730720.1 1913735 R 316385 CDS YP_001730721.1 170081401 6062421 complement(1914550..1915518) 1 NC_010473.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1915518 astE 6062421 astE Escherichia coli str. K-12 substr. DH10B succinylglutamate desuccinylase YP_001730721.1 1914550 R 316385 CDS YP_001730722.1 170081402 6062313 complement(1915511..1916854) 1 NC_010473.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1916854 astB 6062313 astB Escherichia coli str. K-12 substr. DH10B succinylarginine dihydrolase YP_001730722.1 1915511 R 316385 CDS YP_001730723.1 170081403 6061505 complement(1916851..1918329) 1 NC_010473.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1918329 astD 6061505 astD Escherichia coli str. K-12 substr. DH10B succinylglutamic semialdehyde dehydrogenase YP_001730723.1 1916851 R 316385 CDS YP_001730724.1 170081404 6060726 complement(1918326..1919360) 1 NC_010473.1 arginine succinyltransferase 1919360 astA 6060726 astA Escherichia coli str. K-12 substr. DH10B arginine succinyltransferase YP_001730724.1 1918326 R 316385 CDS YP_001730725.1 170081405 6060730 complement(1919357..1920577) 1 NC_010473.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1920577 astC 6060730 astC Escherichia coli str. K-12 substr. DH10B bifunctional succinylornithine transaminase/acetylornithine transaminase YP_001730725.1 1919357 R 316385 CDS YP_001730726.1 170081406 6060661 1921023..1921829 1 NC_010473.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1921829 xthA 6060661 xthA Escherichia coli str. K-12 substr. DH10B exonuclease III YP_001730726.1 1921023 D 316385 CDS YP_001730727.1 170081407 6061486 1921996..1922706 1 NC_010473.1 inner membrane protein 1922706 ydjX 6061486 ydjX Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730727.1 1921996 D 316385 CDS YP_001730728.1 170081408 6061432 1922711..1923388 1 NC_010473.1 hypothetical protein 1923388 ydjY 6061432 ydjY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730728.1 1922711 D 316385 CDS YP_001730729.1 170081409 6061540 1923403..1924110 1 NC_010473.1 inner membrane protein 1924110 ydjZ 6061540 ydjZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730729.1 1923403 D 316385 CDS YP_001730730.1 170081410 6061538 1924110..1924658 1 NC_010473.1 hypothetical protein 1924658 ynjA 6061538 ynjA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730730.1 1924110 D 316385 CDS YP_001730731.1 170081411 6061412 1924668..1925834 1 NC_010473.1 putative ABC transporter solute-binding protein 1925834 ynjB 6061412 ynjB Escherichia coli str. K-12 substr. DH10B putative ABC transporter solute-binding protein YP_001730731.1 1924668 D 316385 CDS YP_001730732.1 170081412 6061571 1925852..1927342 1 NC_010473.1 ABC transporter membrane protein 1927342 ynjC 6061571 ynjC Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001730732.1 1925852 D 316385 CDS YP_001730733.1 170081413 6061578 1927342..1927995 1 NC_010473.1 ABC transporter ATP-binding protein 1927995 ynjD 6061578 ynjD Escherichia coli str. K-12 substr. DH10B ABC transporter ATP-binding protein YP_001730733.1 1927342 D 316385 CDS YP_001730734.1 170081414 6060676 1928062..1929369 1 NC_010473.1 thiosulfate sulfur transferase 1929369 ynjE 6060676 ynjE Escherichia coli str. K-12 substr. DH10B thiosulfate sulfur transferase YP_001730734.1 1928062 D 316385 CDS YP_001730735.1 170081415 6060623 complement(1929378..1929998) 1 NC_010473.1 phosphatidyl transferase, inner membrane protein 1929998 ynjF 6060623 ynjF Escherichia coli str. K-12 substr. DH10B phosphatidyl transferase, inner membrane protein YP_001730735.1 1929378 R 316385 CDS YP_001730736.1 170081416 6060619 1930085..1930492 1 NC_010473.1 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1930492 nudG 6060619 nudG Escherichia coli str. K-12 substr. DH10B pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_001730736.1 1930085 D 316385 CDS YP_001730737.1 170081417 6061518 complement(1930458..1930730) 1 NC_010473.1 hypothetical protein 1930730 ynjH 6061518 ynjH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730737.1 1930458 R 316385 CDS YP_001730738.1 170081418 6061597 1930966..1932309 1 NC_010473.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1932309 gdhA 6061597 gdhA Escherichia coli str. K-12 substr. DH10B glutamate dehydrogenase YP_001730738.1 1930966 D 316385 CDS YP_001730739.1 170081419 6061638 complement(1932426..1933466) 1 NC_010473.1 hypothetical protein 1933466 ynjI 6061638 ynjI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730739.1 1932426 R 316385 CDS YP_001730740.1 170081420 6061647 complement(1933594..1935555) 1 NC_010473.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1935555 topB 6061647 topB Escherichia coli str. K-12 substr. DH10B DNA topoisomerase III YP_001730740.1 1933594 R 316385 CDS YP_001730741.1 170081421 6061609 complement(1935560..1936603) 1 NC_010473.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1936603 selD 6061609 selD Escherichia coli str. K-12 substr. DH10B selenophosphate synthetase YP_001730741.1 1935560 R 316385 CDS YP_001730742.1 170081422 6061570 complement(1936720..1937271) 1 NC_010473.1 hypothetical protein 1937271 ydjA 6061570 ydjA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730742.1 1936720 R 316385 CDS YP_001730743.1 170081423 6061621 1937432..1939288 1 NC_010473.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1939288 sppA 6061621 sppA Escherichia coli str. K-12 substr. DH10B protease 4 YP_001730743.1 1937432 D 316385 CDS YP_001730744.1 170081424 6061673 1939455..1940471 1 NC_010473.1 converts asparagine to aspartate and ammonia; asparaginase 1940471 ansA 6061673 ansA Escherichia coli str. K-12 substr. DH10B asparaginase YP_001730744.1 1939455 D 316385 CDS YP_001730745.1 170081425 6060567 1940482..1941123 1 NC_010473.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1941123 pncA 6060567 pncA Escherichia coli str. K-12 substr. DH10B nicotinamidase/pyrazinamidase YP_001730745.1 1940482 D 316385 CDS YP_001730746.1 170081426 6061675 complement(1941216..1942574) 1 NC_010473.1 transporter 1942574 ydjE 6061675 ydjE Escherichia coli str. K-12 substr. DH10B transporter YP_001730746.1 1941216 R 316385 CDS YP_001730747.1 170081427 6061646 complement(1942691..1943449) 1 NC_010473.1 DNA-binding transcriptional regulator 1943449 ydjF 6061646 ydjF Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730747.1 1942691 R 316385 CDS YP_001730748.1 170081428 6060846 complement(1943586..1944566) 1 NC_010473.1 oxidoreductase 1944566 ydjG 6060846 ydjG Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001730748.1 1943586 R 316385 CDS YP_001730749.1 170081429 6061700 complement(1944576..1945523) 1 NC_010473.1 kinase 1945523 ydjH 6061700 ydjH Escherichia coli str. K-12 substr. DH10B kinase YP_001730749.1 1944576 R 316385 CDS YP_001730750.1 170081430 6062357 complement(1946385..1947428) 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 1947428 ydjJ 6062357 ydjJ Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001730750.1 1946385 R 316385 CDS YP_001730751.1 170081431 6061684 complement(1947445..1948824) 1 NC_010473.1 transporter 1948824 ydjK 6061684 ydjK Escherichia coli str. K-12 substr. DH10B transporter YP_001730751.1 1947445 R 316385 CDS YP_001730752.1 170081432 6061726 complement(1948851..1949927) 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 1949927 ydjL 6061726 ydjL Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001730752.1 1948851 R 316385 CDS YP_001730753.1 170081433 6061739 complement(1950297..1950569) 1 NC_010473.1 hypothetical protein 1950569 yeaC 6061739 yeaC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730753.1 1950297 R 316385 CDS YP_001730754.1 170081434 6060773 complement(1950611..1951024) 1 NC_010473.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1951024 msrB 6060773 msrB Escherichia coli str. K-12 substr. DH10B methionine sulfoxide reductase B YP_001730754.1 1950611 R 316385 CDS YP_001730755.1 170081435 6061690 1951366..1952361 1 NC_010473.1 glyceraldehyde-3-phosphate dehydrogenase 1952361 gapA 6061690 gapA Escherichia coli str. K-12 substr. DH10B glyceraldehyde-3-phosphate dehydrogenase YP_001730755.1 1951366 D 316385 CDS YP_001730756.1 170081436 6061639 1952445..1953329 1 NC_010473.1 hypothetical protein 1953329 yeaD 6061639 yeaD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730756.1 1952445 D 316385 CDS YP_001730757.1 170081437 6062409 complement(1953377..1954231) 1 NC_010473.1 oxidoreductase 1954231 yeaE 6062409 yeaE Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001730757.1 1953377 R 316385 CDS YP_001730758.1 170081438 6061730 complement(1954321..1955067) 1 NC_010473.1 scaffolding protein for murein synthesizing machinery 1955067 mipA 6061730 mipA Escherichia coli str. K-12 substr. DH10B scaffolding protein for murein synthesizing machinery YP_001730758.1 1954321 R 316385 CDS YP_001730759.1 170081439 6061786 1955503..1957437 1 NC_010473.1 hypothetical protein 1957437 yeaG 6061786 yeaG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730759.1 1955503 D 316385 CDS YP_001730760.1 170081440 6060899 1957550..1958833 1 NC_010473.1 hypothetical protein 1958833 yeaH 6060899 yeaH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730760.1 1957550 D 316385 CDS YP_001730761.1 170081441 6061800 1958980..1960455 1 NC_010473.1 diguanylate cyclase 1960455 yeaI 6061800 yeaI Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001730761.1 1958980 D 316385 CDS YP_001730762.1 170081442 6061861 1960636..1962126 1 NC_010473.1 diguanylate cyclase 1962126 yeaJ 6061861 yeaJ Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001730762.1 1960636 D 316385 CDS YP_001730763.1 170081443 6061873 1962169..1962672 1 NC_010473.1 hypothetical protein 1962672 yeaK 6061873 yeaK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730763.1 1962169 D 316385 CDS YP_001730764.1 170081444 6060824 complement(1962673..1962777) 1 NC_010473.1 hypothetical protein 1962777 yoaI 6060824 yoaI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730764.1 1962673 R 316385 CDS YP_001730765.1 170081445 6061890 1962947..1963393 1 NC_010473.1 inner membrane protein 1963393 yeaL 6061890 yeaL Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730765.1 1962947 D 316385 CDS YP_001730766.1 170081446 6061851 complement(1963350..1964171) 1 NC_010473.1 DNA-binding transcriptional regulator 1964171 yeaM 6061851 yeaM Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730766.1 1963350 R 316385 CDS YP_001730767.1 170081447 6061816 1964268..1965449 1 NC_010473.1 transporter 1965449 yeaN 6061816 yeaN Escherichia coli str. K-12 substr. DH10B transporter YP_001730767.1 1964268 D 316385 CDS YP_001730768.1 170081448 6061735 1965504..1965851 1 NC_010473.1 hypothetical protein 1965851 yeaO 6061735 yeaO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730768.1 1965504 D 316385 CDS YP_001730769.1 170081449 6061888 complement(1965873..1966127) 1 NC_010473.1 outer membrane protein 1966127 yoaF 6061888 yoaF Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001730769.1 1965873 R 316385 CDS YP_001730770.1 170081450 6060603 1966310..1967335 1 NC_010473.1 diguanylate cyclase 1967335 yeaP 6060603 yeaP Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001730770.1 1966310 D 316385 CDS YP_001730771.1 170081451 6060605 complement(1967602..1967850) 1 NC_010473.1 hypothetical protein 1967850 yeaQ 6060605 yeaQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730771.1 1967602 R 316385 CDS YP_001730772.1 170081452 6061796 complement(1967998..1968180) 1 NC_010473.1 hypothetical protein 1968180 yoaG 6061796 yoaG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730772.1 1967998 R 316385 CDS YP_001730773.1 170081453 6061892 complement(1968184..1968543) 1 NC_010473.1 hypothetical protein 1968543 yeaR 6061892 yeaR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730773.1 1968184 R 316385 CDS YP_001730774.1 170081454 6061917 complement(1968716..1969354) 1 NC_010473.1 leucine export protein LeuE 1969354 yeaS 6061917 yeaS Escherichia coli str. K-12 substr. DH10B leucine export protein LeuE YP_001730774.1 1968716 R 316385 CDS YP_001730775.1 170081455 6061896 complement(1969481..1970404) 1 NC_010473.1 DNA-binding transcriptional regulator 1970404 yeaT 6061896 yeaT Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730775.1 1969481 R 316385 CDS YP_001730776.1 170081456 6060908 1970507..1971592 1 NC_010473.1 dehydrogenase 1971592 yeaU 6060908 yeaU Escherichia coli str. K-12 substr. DH10B dehydrogenase YP_001730776.1 1970507 D 316385 CDS YP_001730777.1 170081457 6060973 1971783..1973228 1 NC_010473.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; putative transporter 1973228 yeaV 6060973 yeaV Escherichia coli str. K-12 substr. DH10B putative transporter YP_001730777.1 1971783 D 316385 CDS YP_001730778.1 170081458 6060925 1973260..1974384 1 NC_010473.1 2Fe-2S cluster-containing protein 1974384 yeaW 6060925 yeaW Escherichia coli str. K-12 substr. DH10B 2Fe-2S cluster-containing protein YP_001730778.1 1973260 D 316385 CDS YP_001730779.1 170081459 6060982 1974440..1975405 1 NC_010473.1 oxidoreductase 1975405 yeaX 6060982 yeaX Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001730779.1 1974440 D 316385 CDS YP_001730780.1 170081460 6060625 complement(1975459..1976586) 1 NC_010473.1 ribonuclease D 1976586 rnd 6060625 rnd Escherichia coli str. K-12 substr. DH10B ribonuclease D YP_001730780.1 1975459 R 316385 CDS YP_001730781.1 170081461 6061811 complement(1976656..1978341) 1 NC_010473.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1978341 fadD 6061811 fadD Escherichia coli str. K-12 substr. DH10B long-chain-fatty-acid--CoA ligase YP_001730781.1 1976656 R 316385 CDS YP_001730782.1 170081462 6060902 complement(1978546..1979127) 1 NC_010473.1 lipoprotein 1979127 yeaY 6060902 yeaY Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001730782.1 1978546 R 316385 CDS YP_001730783.1 170081463 6061982 complement(1979167..1979862) 1 NC_010473.1 peptidase 1979862 yeaZ 6061982 yeaZ Escherichia coli str. K-12 substr. DH10B peptidase YP_001730783.1 1979167 R 316385 CDS YP_001730784.1 170081464 6060910 complement(1979920..1981830) 1 NC_010473.1 hypothetical protein 1981830 yoaA 6060910 yoaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730784.1 1979920 R 316385 CDS YP_001730785.1 170081465 6062010 1981962..1982306 1 NC_010473.1 hypothetical protein 1982306 yoaB 6062010 yoaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730785.1 1981962 D 316385 CDS YP_001730786.1 170081466 6060879 1982668..1983027 1 NC_010473.1 hypothetical protein 1983027 yoaC 6060879 yoaC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730786.1 1982668 D 316385 CDS YP_001730787.1 170081467 6061994 complement(1983147..1983326) 1 NC_010473.1 hypothetical protein 1983326 yoaH 6061994 yoaH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730787.1 1983147 R 316385 CDS YP_001730788.1 170081468 6062004 1984765..1985343 1 NC_010473.1 hypothetical protein 1985343 yeaB 6062004 yeaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730788.1 1984765 D 316385 CDS YP_001730789.1 170081469 6061041 1985527..1986891 1 NC_010473.1 L-serine deaminase I 1986891 sdaA 6061041 sdaA Escherichia coli str. K-12 substr. DH10B L-serine deaminase I YP_001730789.1 1985527 D 316385 CDS YP_001730790.1 170081470 6061010 1987022..1988620 1 NC_010473.1 phosphodiesterase 1988620 yoaD 6061010 yoaD Escherichia coli str. K-12 substr. DH10B phosphodiesterase YP_001730790.1 1987022 D 316385 CDS YP_001730791.1 170081471 6062058 complement(1988624..1990180) 1 NC_010473.1 fused membrane protein; protein 1990180 yoaE 6062058 yoaE Escherichia coli str. K-12 substr. DH10B fused membrane protein; protein YP_001730791.1 1988624 R 316385 CDS YP_001730792.1 170081472 6062027 1990643..1991614 1 NC_010473.1 fused mannose-specific PTS enzymes: IIA component; IIB component 1991614 manX 6062027 manX Escherichia coli str. K-12 substr. DH10B fused mannose-specific PTS enzymes: IIA component; IIB component YP_001730792.1 1990643 D 316385 CDS YP_001730793.1 170081473 6061060 1991677..1992477 1 NC_010473.1 mannose-specific enzyme IIC component of PTS 1992477 manY 6061060 manY Escherichia coli str. K-12 substr. DH10B mannose-specific enzyme IIC component of PTS YP_001730793.1 1991677 D 316385 CDS YP_001730794.1 170081474 6061024 1992481..1993341 1 NC_010473.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1993341 manZ 6061024 manZ Escherichia coli str. K-12 substr. DH10B PTS system mannose-specific transporter subunit IID YP_001730794.1 1992481 D 316385 CDS YP_001730795.1 170081475 6062042 1993396..1993854 1 NC_010473.1 hypothetical protein 1993854 yobD 6062042 yobD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730795.1 1993396 D 316385 CDS YP_001730796.1 170081476 6062080 1994283..1994849 1 NC_010473.1 membrane protein YebN; hypothetical protein 1994849 yebN 6062080 yebN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730796.1 1994283 D 316385 CDS YP_001730797.1 170081477 6062016 complement(1994846..1995655) 1 NC_010473.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 1995655 rrmA 6062016 rrmA Escherichia coli str. K-12 substr. DH10B 23S rRNA methyltransferase A YP_001730797.1 1994846 R 316385 CDS YP_001730798.1 170081478 6062024 complement(1995821..1996030) 1 NC_010473.1 cold shock-like protein CspC 1996030 cspC 6062024 cspC Escherichia coli str. K-12 substr. DH10B cold shock-like protein CspC YP_001730798.1 1995821 R 316385 CDS YP_001730799.1 170081479 6062026 complement(1996043..1996186) 1 NC_010473.1 hypothetical protein 1996186 yobF 6062026 yobF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730799.1 1996043 R 316385 CDS YP_001730800.1 170081480 6061044 complement(1996856..1997143) 1 NC_010473.1 hypothetical protein 1997143 yebO 6061044 yebO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730800.1 1996856 R 316385 CDS YP_001730801.1 170081481 6061099 complement(1997218..1997361) 1 NC_010473.1 hypothetical protein 1997361 yobG 6061099 yobG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730801.1 1997218 R 316385 CDS YP_001730802.1 170081482 6062110 1997520..1997759 1 NC_010473.1 hypothetical protein 1997759 yobH 6062110 yobH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730802.1 1997520 D 316385 CDS YP_001730803.1 170081483 6061002 complement(1997903..1998694) 1 NC_010473.1 DNA-binding transcriptional regulator 1998694 kdgR 6061002 kdgR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730803.1 1997903 R 316385 CDS YP_001730804.1 170081484 6062048 1998871..2000244 1 NC_010473.1 transporter 2000244 yebQ 6062048 yebQ Escherichia coli str. K-12 substr. DH10B transporter YP_001730804.1 1998871 D 316385 CDS YP_001730805.1 170081485 6062084 complement(2000290..2001171) 1 NC_010473.1 putative metalloprotease; heat shock protein HtpX 2001171 htpX 6062084 htpX Escherichia coli str. K-12 substr. DH10B heat shock protein HtpX YP_001730805.1 2000290 R 316385 CDS YP_001730806.1 170081486 6061112 complement(2001363..2003411) 1 NC_010473.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2003411 prc 6061112 prc Escherichia coli str. K-12 substr. DH10B carboxy-terminal protease YP_001730806.1 2001363 R 316385 CDS YP_001730807.1 170081487 6062130 complement(2003431..2004129) 1 NC_010473.1 affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 2004129 proQ 6062130 proQ Escherichia coli str. K-12 substr. DH10B putative solute/DNA competence effector YP_001730807.1 2003431 R 316385 CDS YP_001730808.1 170081488 6062098 complement(2004226..2004777) 1 NC_010473.1 hypothetical protein 2004777 yebR 6062098 yebR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730808.1 2004226 R 316385 CDS YP_001730809.1 170081489 6061120 2004853..2006136 1 NC_010473.1 inner membrane protein 2006136 yebS 6061120 yebS Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730809.1 2004853 D 316385 CDS YP_001730810.1 170081490 6062113 2006105..2008738 1 NC_010473.1 hypothetical protein 2008738 yebT 6062113 yebT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730810.1 2006105 D 316385 CDS YP_001730811.1 170081491 6060501 2008818..2010257 1 NC_010473.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2010257 yebU 6060501 yebU Escherichia coli str. K-12 substr. DH10B rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_001730811.1 2008818 D 316385 CDS YP_001730812.1 170081492 6060502 2010375..2010611 1 NC_010473.1 hypothetical protein 2010611 yebV 6060502 yebV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730812.1 2010375 D 316385 CDS YP_001730813.1 170081493 6060559 2010716..2010907 1 NC_010473.1 hypothetical protein 2010907 yebW 6060559 yebW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730813.1 2010716 D 316385 CDS YP_001730814.1 170081494 6060425 complement(2010908..2011564) 1 NC_010473.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 2011564 pphA 6060425 pphA Escherichia coli str. K-12 substr. DH10B serine/threonine protein phosphatase 1 YP_001730814.1 2010908 R 316385 CDS YP_001730815.1 170081495 6060951 complement(2011960..2012301) 1 NC_010473.1 hypothetical protein 2012301 yebY 6060951 yebY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730815.1 2011960 R 316385 CDS YP_001730816.1 170081496 6060556 complement(2012314..2013186) 1 NC_010473.1 inner membrane protein 2013186 yebZ 6060556 yebZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730816.1 2012314 R 316385 CDS YP_001730817.1 170081497 6060573 complement(2013190..2013564) 1 NC_010473.1 hypothetical protein 2013564 yobA 6060573 yobA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730817.1 2013190 R 316385 CDS YP_001730818.1 170081498 6060582 2013703..2013933 1 NC_010473.1 DNA polymerase III subunit theta 2013933 holE 6060582 holE Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit theta YP_001730818.1 2013703 D 316385 CDS YP_001730819.1 170081499 6060727 2014035..2014691 1 NC_010473.1 hypothetical protein 2014691 yobB 6060727 yobB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730819.1 2014035 D 316385 CDS YP_001730820.1 170081500 6062232 2014715..2015377 1 NC_010473.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2015377 exoX 6062232 exoX Escherichia coli str. K-12 substr. DH10B exodeoxyribonuclease X YP_001730820.1 2014715 D 316385 CDS YP_001730821.1 170081501 6062424 complement(2015374..2017434) 1 NC_010473.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 2017434 ptrB 6062424 ptrB Escherichia coli str. K-12 substr. DH10B protease 2 YP_001730821.1 2015374 R 316385 CDS YP_001730822.1 170081502 6062386 complement(2017643..2018302) 1 NC_010473.1 hypothetical protein 2018302 yebE 6062386 yebE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730822.1 2017643 R 316385 CDS YP_001730823.1 170081503 6062261 complement(2018629..2018997) 1 NC_010473.1 secreted protein; unknown function; hypothetical protein 2018997 yebF 6062261 yebF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730823.1 2018629 R 316385 CDS YP_001730824.1 170081504 6062208 complement(2019052..2019342) 1 NC_010473.1 DNA damage-inducible protein YebG 2019342 yebG 6062208 yebG Escherichia coli str. K-12 substr. DH10B DNA damage-inducible protein YebG YP_001730824.1 2019052 R 316385 CDS YP_001730825.1 170081505 6058146 2019476..2020654 1 NC_010473.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2020654 purT 6058146 purT Escherichia coli str. K-12 substr. DH10B phosphoribosylglycinamide formyltransferase 2 YP_001730825.1 2019476 D 316385 CDS YP_001730826.1 170081506 6058918 complement(2020710..2021351) 1 NC_010473.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2021351 eda 6058918 eda Escherichia coli str. K-12 substr. DH10B keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001730826.1 2020710 R 316385 CDS YP_001730827.1 170081507 6060736 complement(2021388..2023199) 1 NC_010473.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2023199 edd 6060736 edd Escherichia coli str. K-12 substr. DH10B phosphogluconate dehydratase YP_001730827.1 2021388 R 316385 CDS YP_001730828.1 170081508 6059783 complement(2023434..2024909) 1 NC_010473.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2024909 zwf 6059783 zwf Escherichia coli str. K-12 substr. DH10B glucose-6-phosphate 1-dehydrogenase YP_001730828.1 2023434 R 316385 CDS YP_001730829.1 170081509 6060976 2025247..2026116 1 NC_010473.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2026116 yebK 6060976 yebK Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator HexR YP_001730829.1 2025247 D 316385 CDS YP_001730830.1 170081510 6058790 2026244..2027686 1 NC_010473.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2027686 pykA 6058790 pykA Escherichia coli str. K-12 substr. DH10B pyruvate kinase YP_001730830.1 2026244 D 316385 CDS YP_001730831.1 170081511 6058856 complement(2027817..2028788) 1 NC_010473.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2028788 lpxM 6058856 lpxM Escherichia coli str. K-12 substr. DH10B lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_001730831.1 2027817 R 316385 CDS YP_001730832.1 170081512 6059707 complement(2028908..2030230) 1 NC_010473.1 hypothetical protein 2030230 yebA 6059707 yebA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730832.1 2028908 R 316385 CDS YP_001730833.1 170081513 6059992 complement(2030246..2031178) 1 NC_010473.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 2031178 znuA 6059992 znuA Escherichia coli str. K-12 substr. DH10B high-affinity zinc transporter periplasmic protein YP_001730833.1 2030246 R 316385 CDS YP_001730834.1 170081514 6059673 2031257..2032012 1 NC_010473.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2032012 znuC 6059673 znuC Escherichia coli str. K-12 substr. DH10B high-affinity zinc transporter ATPase YP_001730834.1 2031257 D 316385 CDS YP_001730835.1 170081515 6060956 2032009..2032794 1 NC_010473.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2032794 znuB 6060956 znuB Escherichia coli str. K-12 substr. DH10B high-affinity zinc transporter membrane protein YP_001730835.1 2032009 D 316385 CDS YP_001730836.1 170081516 6062332 complement(2032941..2033951) 1 NC_010473.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2033951 ruvB 6062332 ruvB Escherichia coli str. K-12 substr. DH10B Holliday junction DNA helicase RuvB YP_001730836.1 2032941 R 316385 CDS YP_001730837.1 170081517 6060371 complement(2033960..2034571) 1 NC_010473.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2034571 ruvA 6060371 ruvA Escherichia coli str. K-12 substr. DH10B Holliday junction DNA helicase RuvA YP_001730837.1 2033960 R 316385 CDS YP_001730838.1 170081518 6061958 2034846..2035448 1 NC_010473.1 hypothetical protein 2035448 yebB 6061958 yebB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730838.1 2034846 D 316385 CDS YP_001730839.1 170081519 6058834 complement(2035450..2035971) 1 NC_010473.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2035971 ruvC 6058834 ruvC Escherichia coli str. K-12 substr. DH10B Holliday junction resolvase YP_001730839.1 2035450 R 316385 CDS YP_001730840.1 170081520 6058231 complement(2036006..2036746) 1 NC_010473.1 hypothetical protein 2036746 yebC 6058231 yebC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730840.1 2036006 R 316385 CDS YP_001730841.1 170081521 6058236 complement(2036775..2037227) 1 NC_010473.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2037227 ntpA 6058236 ntpA Escherichia coli str. K-12 substr. DH10B dATP pyrophosphohydrolase YP_001730841.1 2036775 R 316385 CDS YP_001730842.1 170081522 6058283 complement(2037345..2039117) 1 NC_010473.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2039117 aspS 6058283 aspS Escherichia coli str. K-12 substr. DH10B aspartyl-tRNA synthetase YP_001730842.1 2037345 R 316385 CDS YP_001730843.1 170081523 6058316 2039427..2039993 1 NC_010473.1 hypothetical protein 2039993 yecD 6058316 yecD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730843.1 2039427 D 316385 CDS YP_001730844.1 170081524 6058352 2039990..2040808 1 NC_010473.1 hypothetical protein 2040808 yecE 6058352 yecE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730844.1 2039990 D 316385 CDS YP_001730845.1 170081525 6058391 2040861..2041256 1 NC_010473.1 inner membrane protein 2041256 yecN 6058391 yecN Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730845.1 2040861 D 316385 CDS YP_001730846.1 170081526 6058396 2041297..2042040 1 NC_010473.1 methyltransferase 2042040 yecO 6058396 yecO Escherichia coli str. K-12 substr. DH10B methyltransferase YP_001730846.1 2041297 D 316385 CDS YP_001730847.1 170081527 6058227 2042037..2043008 1 NC_010473.1 S-adenosyl-L-methionine-dependent methyltransferase 2043008 yecP 6058227 yecP Escherichia coli str. K-12 substr. DH10B S-adenosyl-L-methionine-dependent methyltransferase YP_001730847.1 2042037 D 316385 CDS YP_001730848.1 170081528 6058416 complement(2043173..2045602) 1 NC_010473.1 trimethylamine N-oxide reductase system III, catalytic subunit 2045602 torZ 6058416 torZ Escherichia coli str. K-12 substr. DH10B trimethylamine N-oxide reductase system III, catalytic subunit YP_001730848.1 2043173 R 316385 CDS YP_001730849.1 170081529 6058481 complement(2045627..2046727) 1 NC_010473.1 TMAO reductase III (TorYZ), cytochrome c-type subunit 2046727 torY 6058481 torY Escherichia coli str. K-12 substr. DH10B TMAO reductase III (TorYZ), cytochrome c-type subunit YP_001730849.1 2045627 R 316385 CDS YP_001730850.1 170081530 6058491 complement(2047115..2047861) 1 NC_010473.1 copper homeostasis protein CutC 2047861 cutC 6058491 cutC Escherichia coli str. K-12 substr. DH10B copper homeostasis protein CutC YP_001730850.1 2047115 R 316385 CDS YP_001730851.1 170081531 6058516 complement(2047875..2048441) 1 NC_010473.1 hypothetical protein 2048441 yecM 6058516 yecM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730851.1 2047875 R 316385 CDS YP_001730852.1 170081532 6058537 2048657..2050390 1 NC_010473.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2050390 argS 6058537 argS Escherichia coli str. K-12 substr. DH10B arginyl-tRNA synthetase YP_001730852.1 2048657 D 316385 CDS YP_001730853.1 170081533 6060242 2050567..2051055 1 NC_010473.1 hypothetical protein 2051055 yecT 6060242 yecT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730853.1 2050567 D 316385 CDS YP_001730854.1 170081534 6058559 complement(2051175..2051567) 1 NC_010473.1 hypothetical protein 2051567 flhE 6058559 flhE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730854.1 2051175 R 316385 CDS YP_001730855.1 170081535 6058600 complement(2051567..2053645) 1 NC_010473.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2053645 flhA 6058600 flhA Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis protein FlhA YP_001730855.1 2051567 R 316385 CDS YP_001730856.1 170081536 6058614 complement(2053638..2054786) 1 NC_010473.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2054786 flhB 6058614 flhB Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis protein FlhB YP_001730856.1 2053638 R 316385 CDS YP_001730857.1 170081537 6058615 complement(2054988..2055632) 1 NC_010473.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 2055632 cheZ 6058615 cheZ Escherichia coli str. K-12 substr. DH10B chemotaxis regulator CheZ YP_001730857.1 2054988 R 316385 CDS YP_001730858.1 170081538 6058620 complement(2055643..2056032) 1 NC_010473.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 2056032 cheY 6058620 cheY Escherichia coli str. K-12 substr. DH10B chemotaxis regulatory protein CheY YP_001730858.1 2055643 R 316385 CDS YP_001730859.1 170081539 6058625 complement(2056047..2057096) 1 NC_010473.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 2057096 cheB 6058625 cheB Escherichia coli str. K-12 substr. DH10B chemotaxis-specific methylesterase YP_001730859.1 2056047 R 316385 CDS YP_001730860.1 170081540 6058622 complement(2057099..2057959) 1 NC_010473.1 methylates the MCP; chemotaxis methyltransferase CheR 2057959 cheR 6058622 cheR Escherichia coli str. K-12 substr. DH10B chemotaxis methyltransferase CheR YP_001730860.1 2057099 R 316385 CDS YP_001730861.1 170081541 6058631 complement(2057978..2059579) 1 NC_010473.1 mediates taxis toward dipeptides; methyl-accepting protein IV 2059579 tap 6058631 tap Escherichia coli str. K-12 substr. DH10B methyl-accepting protein IV YP_001730861.1 2057978 R 316385 CDS YP_001730862.1 170081542 6058628 complement(2059625..2061286) 1 NC_010473.1 methyl-accepting chemotaxis protein II 2061286 tar 6058628 tar Escherichia coli str. K-12 substr. DH10B methyl-accepting chemotaxis protein II YP_001730862.1 2059625 R 316385 CDS YP_001730863.1 170081543 6058633 complement(2061431..2061934) 1 NC_010473.1 purine-binding chemotaxis protein 2061934 cheW 6058633 cheW Escherichia coli str. K-12 substr. DH10B purine-binding chemotaxis protein YP_001730863.1 2061431 R 316385 CDS YP_001730864.1 170081544 6058648 complement(2063924..2064850) 1 NC_010473.1 protein that enables flagellar motor rotation; with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2064850 motB 6058648 motB Escherichia coli str. K-12 substr. DH10B flagellar motor protein MotB YP_001730864.1 2063924 R 316385 CDS YP_001730865.1 170081545 6058650 complement(2064847..2065734) 1 NC_010473.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2065734 motA 6058650 motA Escherichia coli str. K-12 substr. DH10B flagellar motor protein MotA YP_001730865.1 2064847 R 316385 CDS YP_001730866.1 170081546 6058651 complement(2066456..2066815) 1 NC_010473.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 2066815 flhD 6058651 flhD Escherichia coli str. K-12 substr. DH10B transcriptional activator FlhD YP_001730866.1 2066456 R 316385 CDS YP_001730867.1 170081547 6058656 2068785..2069213 1 NC_010473.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2069213 yecG 6058656 yecG Escherichia coli str. K-12 substr. DH10B universal stress protein UspC YP_001730867.1 2068785 D 316385 CDS YP_001730868.1 170081548 6058632 complement(2069220..2070644) 1 NC_010473.1 trehalose-6-phosphate synthase 2070644 otsA 6058632 otsA Escherichia coli str. K-12 substr. DH10B trehalose-6-phosphate synthase YP_001730868.1 2069220 R 316385 CDS YP_001730869.1 170081549 6058660 complement(2070619..2071419) 1 NC_010473.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 2071419 otsB 6058660 otsB Escherichia coli str. K-12 substr. DH10B trehalose-6-phosphate phosphatase YP_001730869.1 2070619 R 316385 CDS YP_001730870.1 170081550 6058663 complement(2071586..2072575) 1 NC_010473.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 2072575 araH 6058663 araH Escherichia coli str. K-12 substr. DH10B L-arabinose transporter permease YP_001730870.1 2071586 R 316385 CDS YP_001730871.1 170081551 6058669 complement(2072587..2074101) 1 NC_010473.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2074101 araG 6058669 araG Escherichia coli str. K-12 substr. DH10B L-arabinose transporter ATP-binding protein YP_001730871.1 2072587 R 316385 CDS YP_001730872.1 170081552 6058822 complement(2074171..2075160) 1 NC_010473.1 periplasmic-binding component of L-arabinose ABC transporter (precursor) 2075160 araF 6058822 araF Escherichia coli str. K-12 substr. DH10B periplasmic-binding component of L-arabinose ABC transporter (precursor) YP_001730872.1 2074171 R 316385 CDS YP_001730873.1 170081553 6058672 2075957..2076460 1 NC_010473.1 ferritin-like protein 2076460 yecI 6058672 yecI Escherichia coli str. K-12 substr. DH10B ferritin-like protein YP_001730873.1 2075957 D 316385 CDS YP_001730874.1 170081554 6058696 complement(2076539..2076790) 1 NC_010473.1 hypothetical protein 2076790 yecJ 6058696 yecJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730874.1 2076539 R 316385 CDS YP_001730875.1 170081555 6058910 2077254..2077577 1 NC_010473.1 hypothetical protein 2077577 yecR 6058910 yecR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730875.1 2077254 D 316385 CDS YP_001730876.1 170081556 6058709 2077748..2078245 1 NC_010473.1 cytoplasmic iron storage protein; ferritin 2078245 ftn 6058709 ftn Escherichia coli str. K-12 substr. DH10B ferritin YP_001730876.1 2077748 D 316385 CDS YP_001730877.1 170081557 6059659 complement(2078283..2078522) 1 NC_010473.1 hypothetical protein 2078522 yecH 6059659 yecH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730877.1 2078283 R 316385 CDS YP_001730878.1 170081558 6059780 2078713..2079924 1 NC_010473.1 tyrosine transporter 2079924 tyrP 6059780 tyrP Escherichia coli str. K-12 substr. DH10B tyrosine transporter YP_001730878.1 2078713 D 316385 CDS YP_001730879.1 170081559 6058717 complement(2079986..2080651) 1 NC_010473.1 hypothetical protein 2080651 yecA 6058717 yecA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730879.1 2079986 R 316385 CDS YP_001730880.1 170081560 6060196 complement(2081301..2081849) 1 NC_010473.1 phosphatidylglycerophosphate synthetase 2081849 pgsA 6060196 pgsA Escherichia coli str. K-12 substr. DH10B phosphatidylglycerophosphate synthetase YP_001730880.1 2081301 R 316385 CDS YP_001730881.1 170081561 6058725 complement(2081906..2083738) 1 NC_010473.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2083738 uvrC 6058725 uvrC Escherichia coli str. K-12 substr. DH10B excinuclease ABC subunit C YP_001730881.1 2081906 R 316385 CDS YP_001730882.1 170081562 6058729 complement(2083735..2084391) 1 NC_010473.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2084391 uvrY 6058729 uvrY Escherichia coli str. K-12 substr. DH10B response regulator YP_001730882.1 2083735 R 316385 CDS YP_001730883.1 170081563 6058734 2084850..2085074 1 NC_010473.1 hypothetical protein 2085074 yecF 6058734 yecF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730883.1 2084850 D 316385 CDS YP_001730884.1 170081564 6058780 complement(2085142..2085864) 1 NC_010473.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2085864 sdiA 6058780 sdiA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator SdiA YP_001730884.1 2085142 R 316385 CDS YP_001730885.1 170081565 6058786 complement(2086094..2086846) 1 NC_010473.1 putative amino-acid ABC transporter ATP-binding protein YecC 2086846 yecC 6058786 yecC Escherichia coli str. K-12 substr. DH10B putative amino-acid ABC transporter ATP-binding protein YecC YP_001730885.1 2086094 R 316385 CDS YP_001730886.1 170081566 6058787 complement(2086843..2087511) 1 NC_010473.1 ABC transporter membrane protein 2087511 yecS 6058787 yecS Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001730886.1 2086843 R 316385 CDS YP_001730887.1 170081567 6058788 complement(2087526..2088512) 1 NC_010473.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2088512 dcyD 6058788 dcyD Escherichia coli str. K-12 substr. DH10B D-cysteine desulfhydrase YP_001730887.1 2087526 R 316385 CDS YP_001730888.1 170081568 6058789 complement(2088617..2089417) 1 NC_010473.1 cystine transporter subunit 2089417 fliY 6058789 fliY Escherichia coli str. K-12 substr. DH10B cystine transporter subunit YP_001730888.1 2088617 R 316385 CDS YP_001730889.1 170081569 6058809 complement(2089505..2090056) 1 NC_010473.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2090056 fliZ 6058809 fliZ Escherichia coli str. K-12 substr. DH10B flagella biosynthesis protein FliZ YP_001730889.1 2089505 R 316385 CDS YP_001730890.1 170081570 6058815 complement(2090102..2090821) 1 NC_010473.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2090821 fliA 6058815 fliA Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis sigma factor YP_001730890.1 2090102 R 316385 CDS YP_001730891.1 170081571 6058818 2092904..2094310 1 NC_010473.1 involved in flagellin assembly; flagellar capping protein 2094310 fliD 6058818 fliD Escherichia coli str. K-12 substr. DH10B flagellar capping protein YP_001730891.1 2092904 D 316385 CDS YP_001730892.1 170081572 6058841 2094335..2094745 1 NC_010473.1 flagellin specific chaperone; flagellar protein FliS 2094745 fliS 6058841 fliS Escherichia coli str. K-12 substr. DH10B flagellar protein FliS YP_001730892.1 2094335 D 316385 CDS YP_001730893.1 170081573 6058847 2094745..2095110 1 NC_010473.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2095110 fliT 6058847 fliT Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis protein FliT YP_001730893.1 2094745 D 316385 CDS YP_001730894.1 170081574 6058848 2095188..2096675 1 NC_010473.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2096675 amyA 6058848 amyA Escherichia coli str. K-12 substr. DH10B alpha-amylase YP_001730894.1 2095188 D 316385 CDS YP_001730895.1 170081575 6058851 complement(2096709..2097122) 1 NC_010473.1 hypothetical protein 2097122 yedD 6058851 yedD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730895.1 2096709 R 316385 CDS YP_001730896.1 170081576 6058852 2097309..2098514 1 NC_010473.1 putative inner membrane protein 2098514 yedE 6058852 yedE Escherichia coli str. K-12 substr. DH10B putative inner membrane protein YP_001730896.1 2097309 D 316385 CDS YP_001730897.1 170081577 6058854 2098511..2098744 1 NC_010473.1 hypothetical protein 2098744 yedF 6058854 yedF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730897.1 2098511 D 316385 CDS YP_001730898.1 170081578 6058865 2098853..2099521 1 NC_010473.1 hypothetical protein 2099521 yedK 6058865 yedK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730898.1 2098853 D 316385 CDS YP_001730899.1 170081579 6058869 2099632..2100111 1 NC_010473.1 acyltransferase 2100111 yedL 6058869 yedL Escherichia coli str. K-12 substr. DH10B acyltransferase YP_001730899.1 2099632 D 316385 CDS YP_001730900.1 170081580 6058897 complement(2101033..2101383) 1 NC_010473.1 hypothetical protein 2101383 yedM 6058897 yedM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730900.1 2101033 R 316385 CDS YP_001730901.1 170081581 6059128 complement(2101732..2102046) 1 NC_010473.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2102046 fliE 6059128 fliE Escherichia coli str. K-12 substr. DH10B flagellar hook-basal body protein FliE YP_001730901.1 2101732 R 316385 CDS YP_001730902.1 170081582 6058900 2102261..2103919 1 NC_010473.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2103919 fliF 6058900 fliF Escherichia coli str. K-12 substr. DH10B flagellar MS-ring protein YP_001730902.1 2102261 D 316385 CDS YP_001730903.1 170081583 6058907 2103912..2104907 1 NC_010473.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2104907 fliG 6058907 fliG Escherichia coli str. K-12 substr. DH10B flagellar motor switch protein G YP_001730903.1 2103912 D 316385 CDS YP_001730904.1 170081584 6058917 2104900..2105586 1 NC_010473.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2105586 fliH 6058917 fliH Escherichia coli str. K-12 substr. DH10B flagellar assembly protein H YP_001730904.1 2104900 D 316385 CDS YP_001730905.1 170081585 6058927 2105586..2106959 1 NC_010473.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2106959 fliI 6058927 fliI Escherichia coli str. K-12 substr. DH10B flagellum-specific ATP synthase YP_001730905.1 2105586 D 316385 CDS YP_001730906.1 170081586 6058942 2106978..2107421 1 NC_010473.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2107421 fliJ 6058942 fliJ Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis chaperone YP_001730906.1 2106978 D 316385 CDS YP_001730907.1 170081587 6058944 2107418..2108545 1 NC_010473.1 flagellar hook-length control protein 2108545 fliK 6058944 fliK Escherichia coli str. K-12 substr. DH10B flagellar hook-length control protein YP_001730907.1 2107418 D 316385 CDS YP_001730908.1 170081588 6058951 2108650..2109114 1 NC_010473.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2109114 fliL 6058951 fliL Escherichia coli str. K-12 substr. DH10B flagellar basal body-associated protein FliL YP_001730908.1 2108650 D 316385 CDS YP_001730909.1 170081589 6058954 2109119..2110123 1 NC_010473.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2110123 fliM 6058954 fliM Escherichia coli str. K-12 substr. DH10B flagellar motor switch protein FliM YP_001730909.1 2109119 D 316385 CDS YP_001730910.1 170081590 6058975 2110120..2110533 1 NC_010473.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2110533 fliN 6058975 fliN Escherichia coli str. K-12 substr. DH10B flagellar motor switch protein FliN YP_001730910.1 2110120 D 316385 CDS YP_001730911.1 170081591 6058986 2110536..2110901 1 NC_010473.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2110901 fliO 6058986 fliO Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis protein FliO YP_001730911.1 2110536 D 316385 CDS YP_001730912.1 170081592 6059001 2110901..2111638 1 NC_010473.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2111638 fliP 6059001 fliP Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis protein FliP YP_001730912.1 2110901 D 316385 CDS YP_001730913.1 170081593 6059019 2111648..2111917 1 NC_010473.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2111917 fliQ 6059019 fliQ Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis protein FliQ YP_001730913.1 2111648 D 316385 CDS YP_001730914.1 170081594 6059021 2111925..2112710 1 NC_010473.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2112710 fliR 6059021 fliR Escherichia coli str. K-12 substr. DH10B flagellar biosynthesis protein FliR YP_001730914.1 2111925 D 316385 CDS YP_001730915.1 170081595 6059025 2113000..2113623 1 NC_010473.1 DNA-binding transcriptional activator, co-regulator with RcsB 2113623 rcsA 6059025 rcsA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator, co-regulator with RcsB YP_001730915.1 2113000 D 316385 CDS YP_001730916.1 170081596 6059033 complement(2113667..2113855) 1 NC_010473.1 hypothetical protein 2113855 dsrB 6059033 dsrB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730916.1 2113667 R 316385 CDS YP_001730917.1 170081597 6059038 2114018..2114245 1 NC_010473.1 hypothetical protein 2114245 yodD 6059038 yodD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730917.1 2114018 D 316385 CDS YP_001730918.1 170081598 6058946 2114543..2115358 1 NC_010473.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2115358 yedP 6058946 yedP Escherichia coli str. K-12 substr. DH10B mannosyl-3-phosphoglycerate phosphatase YP_001730918.1 2114543 D 316385 CDS YP_001730919.1 170081599 6059077 complement(2115355..2117049) 1 NC_010473.1 diguanylate cyclase 2117049 yedQ 6059077 yedQ Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001730919.1 2115355 R 316385 CDS YP_001730920.1 170081600 6059079 complement(2117220..2117402) 1 NC_010473.1 hypothetical protein 2117402 yodC 6059079 yodC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730920.1 2117220 R 316385 CDS YP_001730921.1 170081601 6059082 complement(2117481..2118398) 1 NC_010473.1 hypothetical protein 2118398 yedI 6059082 yedI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730921.1 2117481 R 316385 CDS YP_001730922.1 170081602 6059092 2118571..2119491 1 NC_010473.1 hypothetical protein 2119491 yedA 6059092 yedA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730922.1 2118571 D 316385 CDS YP_001730923.1 170081603 6059095 complement(2119480..2119950) 1 NC_010473.1 DNA mismatch endonuclease of very short patch repair 2119950 vsr 6059095 vsr Escherichia coli str. K-12 substr. DH10B DNA mismatch endonuclease of very short patch repair YP_001730923.1 2119480 R 316385 CDS YP_001730924.1 170081604 6059099 complement(2119931..2121349) 1 NC_010473.1 DNA cytosine methylase 2121349 dcm 6059099 dcm Escherichia coli str. K-12 substr. DH10B DNA cytosine methylase YP_001730924.1 2119931 R 316385 CDS YP_001730925.1 170081605 6059110 complement(2121416..2122111) 1 NC_010473.1 hypothetical protein 2122111 yedJ 6059110 yedJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730925.1 2121416 R 316385 CDS YP_001730926.1 170081606 6059113 complement(2122151..2122516) 1 NC_010473.1 inner membrane protein 2122516 yedR 6059113 yedR Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730926.1 2122151 R 316385 CDS YP_001730927.1 170081607 6059114 2124867..2125718 1 NC_010473.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2125718 hchA 6059114 hchA Escherichia coli str. K-12 substr. DH10B chaperone protein HchA YP_001730927.1 2124867 D 316385 CDS YP_001730928.1 170081608 6059118 complement(2125826..2127184) 1 NC_010473.1 sensory kinase in two-component regulatory system with YedW 2127184 yedV 6059118 yedV Escherichia coli str. K-12 substr. DH10B sensory kinase in two-component regulatory system with YedW YP_001730928.1 2125826 R 316385 CDS YP_001730929.1 170081609 6059126 complement(2127184..2127855) 1 NC_010473.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2127855 yedW 6059126 yedW Escherichia coli str. K-12 substr. DH10B transcriptional regulatory protein YedW YP_001730929.1 2127184 R 316385 CDS YP_001730930.1 170081610 6059127 2127988..2128401 1 NC_010473.1 hypothetical protein 2128401 yedX 6059127 yedX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730930.1 2127988 D 316385 CDS YP_001730931.1 170081611 6059161 2129515..2130150 1 NC_010473.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 2130150 yedZ 6059161 yedZ Escherichia coli str. K-12 substr. DH10B putative sulfite oxidase subunit YedZ YP_001730931.1 2129515 D 316385 CDS YP_001730932.1 170081612 6059163 2130407..2131057 1 NC_010473.1 hypothetical protein 2131057 yodA 6059163 yodA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730932.1 2130407 D 316385 CDS YP_001730933.1 170081613 6059164 2131400..2131930 1 NC_010473.1 cytochrome 2131930 yodB 6059164 yodB Escherichia coli str. K-12 substr. DH10B cytochrome YP_001730933.1 2131400 D 316385 CDS YP_001730934.1 170081614 6059210 2132683..2133480 1 NC_010473.1 hypothetical protein 2133480 yeeI 6059210 yeeI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730934.1 2132683 D 316385 CDS YP_001730935.1 170081615 6058719 2133943..2141046 1 NC_010473.1 adhesin 2141046 yeeJ 6058719 yeeJ Escherichia coli str. K-12 substr. DH10B adhesin YP_001730935.1 2133943 D 316385 CDS YP_001730936.1 170081616 6059175 2142675..2143991 1 NC_010473.1 shikimate transporter 2143991 shiA 6059175 shiA Escherichia coli str. K-12 substr. DH10B shikimate transporter YP_001730936.1 2142675 D 316385 CDS YP_001730937.1 170081617 6059191 2144093..2145547 1 NC_010473.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2145547 amn 6059191 amn Escherichia coli str. K-12 substr. DH10B AMP nucleosidase YP_001730937.1 2144093 D 316385 CDS YP_001730938.1 170081618 6059209 2145890..2146606 1 NC_010473.1 hypothetical protein 2146606 yeeN 6059209 yeeN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730938.1 2145890 D 316385 CDS YP_001730939.1 170081619 6060015 complement(2147235..2148878) 1 NC_010473.1 hypothetical protein 2148878 yeeO 6060015 yeeO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730939.1 2147235 R 316385 CDS YP_001730940.1 170081620 6062043 complement(2148996..2149946) 1 NC_010473.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2149946 cbl 6062043 cbl Escherichia coli str. K-12 substr. DH10B transcriptional regulator Cbl YP_001730940.1 2148996 R 316385 CDS YP_001730941.1 170081621 6059224 complement(2150048..2150965) 1 NC_010473.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2150965 nac 6059224 nac Escherichia coli str. K-12 substr. DH10B nitrogen assimilation transcriptional regulator YP_001730941.1 2150048 R 316385 CDS YP_001730942.1 170081622 6062315 complement(2151423..2152355) 1 NC_010473.1 hypothetical protein 2152355 erfK 6062315 erfK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730942.1 2151423 R 316385 CDS YP_001730943.1 170081623 6059234 complement(2152420..2153499) 1 NC_010473.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2153499 cobT 6059234 cobT Escherichia coli str. K-12 substr. DH10B nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_001730943.1 2152420 R 316385 CDS YP_001730944.1 170081624 6059236 complement(2153511..2154254) 1 NC_010473.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2154254 cobS 6059236 cobS Escherichia coli str. K-12 substr. DH10B cobalamin synthase YP_001730944.1 2153511 R 316385 CDS YP_001730945.1 170081625 6059245 complement(2154251..2154796) 1 NC_010473.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 2154796 cobU 6059245 cobU Escherichia coli str. K-12 substr. DH10B adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_001730945.1 2154251 R 316385 CDS YP_001730946.1 170081626 6059260 complement(2155337..2156353) 1 NC_010473.1 CP4-44 prophage; IS5 transposase and trans-activator 2156353 insH-6 6059260 insH-6 Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; IS5 transposase and trans-activator YP_001730946.1 2155337 R 316385 CDS YP_001730947.1 170081627 6059268 complement(2157984..2158889) 1 NC_010473.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 2158889 insD-3 6059268 insD-3 Escherichia coli str. K-12 substr. DH10B insertion element IS2 transposase InsD YP_001730947.1 2157984 R 316385 CDS YP_001730948.1 170081628 6059271 complement(2158847..2159257) 1 NC_010473.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 2159257 insC-3 6059271 insC-3 Escherichia coli str. K-12 substr. DH10B insertion sequence 2 OrfA protein YP_001730948.1 2158847 R 316385 CDS YP_001730949.1 170081629 6062384 2160571..2163690 1 NC_010473.1 CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter 2163690 flu 6062384 flu Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter YP_001730949.1 2160571 D 316385 CDS YP_001730950.1 170081630 6059288 2163811..2165343 1 NC_010473.1 CP4-44 prophage; membrane protein 2165343 yeeR 6059288 yeeR Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; membrane protein YP_001730950.1 2163811 D 316385 CDS YP_001730951.1 170081631 6059296 2165340..2165786 1 NC_010473.1 CP4-44 prophage; DNA repair protein 2165786 yeeS 6059296 yeeS Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; DNA repair protein YP_001730951.1 2165340 D 316385 CDS YP_001730952.1 170081632 6059302 2165849..2166070 1 NC_010473.1 CP4-44 prophage; protein 2166070 yeeT 6059302 yeeT Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; protein YP_001730952.1 2165849 D 316385 CDS YP_001730953.1 170081633 6059303 2166144..2166512 1 NC_010473.1 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 2166512 yeeU 6059303 yeeU Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system YP_001730953.1 2166144 D 316385 CDS YP_001730954.1 170081634 6059307 2166601..2166975 1 NC_010473.1 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system 2166975 yeeV 6059307 yeeV Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system YP_001730954.1 2166601 D 316385 CDS YP_001730955.1 170081635 6059311 2166972..2167166 1 NC_010473.1 CP4-44 prophage; protein 2167166 yeeW 6059311 yeeW Escherichia coli str. K-12 substr. DH10B CP4-44 prophage; protein YP_001730955.1 2166972 D 316385 CDS YP_001730956.1 170081636 6059323 2167607..2167963 1 NC_010473.1 hypothetical protein 2167963 yoeF 6059323 yoeF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730956.1 2167607 D 316385 CDS YP_001730957.1 170081637 6059332 complement(2168064..2168459) 1 NC_010473.1 hypothetical protein 2168459 yeeX 6059332 yeeX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730957.1 2168064 R 316385 CDS YP_001730958.1 170081638 6059340 complement(2168565..2169623) 1 NC_010473.1 inner membrane protein 2169623 yeeA 6059340 yeeA Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730958.1 2168565 R 316385 CDS YP_001730959.1 170081639 6059347 complement(2169821..2170294) 1 NC_010473.1 DNA gyrase inhibitor 2170294 sbmC 6059347 sbmC Escherichia coli str. K-12 substr. DH10B DNA gyrase inhibitor YP_001730959.1 2169821 R 316385 CDS YP_001730960.1 170081640 6059350 complement(2170413..2171579) 1 NC_010473.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2171579 dacD 6059350 dacD Escherichia coli str. K-12 substr. DH10B D-alanyl-D-alanine carboxypeptidase YP_001730960.1 2170413 R 316385 CDS YP_001730961.1 170081641 6059358 2171788..2173215 1 NC_010473.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2173215 sbcB 6059358 sbcB Escherichia coli str. K-12 substr. DH10B exonuclease I YP_001730961.1 2171788 D 316385 CDS YP_001730962.1 170081642 6059360 complement(2173258..2173485) 1 NC_010473.1 hypothetical protein 2173485 yeeD 6059360 yeeD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730962.1 2173258 R 316385 CDS YP_001730963.1 170081643 6059362 complement(2173499..2174557) 1 NC_010473.1 inner membrane protein 2174557 yeeE 6059362 yeeE Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001730963.1 2173499 R 316385 CDS YP_001730964.1 170081644 6059363 complement(2174736..2176094) 1 NC_010473.1 amino-acid transporter 2176094 yeeF 6059363 yeeF Escherichia coli str. K-12 substr. DH10B amino-acid transporter YP_001730964.1 2174736 R 316385 CDS YP_001730965.1 170081645 6059364 complement(2176361..2177290) 1 NC_010473.1 DNA-binding transcriptional regulator 2177290 yeeY 6059364 yeeY Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001730965.1 2176361 R 316385 CDS YP_001730966.1 170081646 6059366 complement(2177336..2178160) 1 NC_010473.1 epimerase 2178160 yeeZ 6059366 yeeZ Escherichia coli str. K-12 substr. DH10B epimerase YP_001730966.1 2177336 R 316385 CDS YP_001730967.1 170081647 6059368 complement(2178243..2178497) 1 NC_010473.1 toxin of the YoeB-YefM toxin-antitoxin system 2178497 yoeB 6059368 yoeB Escherichia coli str. K-12 substr. DH10B toxin of the YoeB-YefM toxin-antitoxin system YP_001730967.1 2178243 R 316385 CDS YP_001730968.1 170081648 6059381 complement(2178494..2178745) 1 NC_010473.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 2178745 yefM 6059381 yefM Escherichia coli str. K-12 substr. DH10B antitoxin YefM YP_001730968.1 2178494 R 316385 CDS YP_001730970.1 170081650 6059384 2179224..2180123 1 NC_010473.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2180123 hisG 6059384 hisG Escherichia coli str. K-12 substr. DH10B ATP phosphoribosyltransferase YP_001730970.1 2179224 D 316385 CDS YP_001730971.1 170081651 6059387 2180129..2181433 1 NC_010473.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2181433 hisD 6059387 hisD Escherichia coli str. K-12 substr. DH10B histidinol dehydrogenase YP_001730971.1 2180129 D 316385 CDS YP_001730972.1 170081652 6059393 2181430..2182500 1 NC_010473.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2182500 hisC 6059393 hisC Escherichia coli str. K-12 substr. DH10B histidinol-phosphate aminotransferase YP_001730972.1 2181430 D 316385 CDS YP_001730973.1 170081653 6059394 2182500..2183567 1 NC_010473.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2183567 hisB 6059394 hisB Escherichia coli str. K-12 substr. DH10B imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_001730973.1 2182500 D 316385 CDS YP_001730974.1 170081654 6059418 2183567..2184157 1 NC_010473.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2184157 hisH 6059418 hisH Escherichia coli str. K-12 substr. DH10B imidazole glycerol phosphate synthase subunit HisH YP_001730974.1 2183567 D 316385 CDS YP_001730975.1 170081655 6059421 2184157..2184894 1 NC_010473.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2184894 hisA 6059421 hisA Escherichia coli str. K-12 substr. DH10B 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_001730975.1 2184157 D 316385 CDS YP_001730976.1 170081656 6059433 2184876..2185652 1 NC_010473.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2185652 hisF 6059433 hisF Escherichia coli str. K-12 substr. DH10B imidazole glycerol phosphate synthase subunit HisF YP_001730976.1 2184876 D 316385 CDS YP_001730977.1 170081657 6059450 2185646..2186257 1 NC_010473.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2186257 hisI 6059450 hisI Escherichia coli str. K-12 substr. DH10B bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_001730977.1 2185646 D 316385 CDS YP_001730978.1 170081658 6059452 complement(2186353..2187333) 1 NC_010473.1 regulator of length of O-antigen component of lipopolysaccharide chains 2187333 cld 6059452 cld Escherichia coli str. K-12 substr. DH10B regulator of length of O-antigen component of lipopolysaccharide chains YP_001730978.1 2186353 R 316385 CDS YP_001730979.1 170081659 6059458 complement(2187479..2188645) 1 NC_010473.1 UDP-glucose 6-dehydrogenase 2188645 ugd 6059458 ugd Escherichia coli str. K-12 substr. DH10B UDP-glucose 6-dehydrogenase YP_001730979.1 2187479 R 316385 CDS YP_001730980.1 170081660 6059459 complement(2188894..2190300) 1 NC_010473.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2190300 gnd 6059459 gnd Escherichia coli str. K-12 substr. DH10B 6-phosphogluconate dehydrogenase YP_001730980.1 2188894 R 316385 CDS YP_001730981.1 170081661 6059463 complement(2190927..2191943) 1 NC_010473.1 IS5 transposase and trans-activator 2191943 insH-7 6059463 insH-7 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001730981.1 2190927 R 316385 CDS YP_001730982.1 170081662 6059468 complement(2192423..2193541) 1 NC_010473.1 lipopolysaccharide biosynthesis protein 2193541 wbbK 6059468 wbbK Escherichia coli str. K-12 substr. DH10B lipopolysaccharide biosynthesis protein YP_001730982.1 2192423 R 316385 CDS YP_001730983.1 170081663 6059472 complement(2193526..2194116) 1 NC_010473.1 WbbJ; catalyzes the transfer of the O-acetyl moiety to the O antigen; part of the lipopolysaccharide biosynthetic pathway; putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ 2194116 wbbJ 6059472 wbbJ Escherichia coli str. K-12 substr. DH10B putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ YP_001730983.1 2193526 R 316385 CDS YP_001730984.1 170081664 6059478 complement(2194097..2195089) 1 NC_010473.1 hypothetical protein 2195089 wbbI 6059478 wbbI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001730984.1 2194097 R 316385 CDS YP_001730985.1 170081665 6059489 complement(2195092..2196258) 1 NC_010473.1 O-antigen polymerase 2196258 wbbH 6059489 wbbH Escherichia coli str. K-12 substr. DH10B O-antigen polymerase YP_001730985.1 2195092 R 316385 CDS YP_001730986.1 170081666 6059501 complement(2196258..2197361) 1 NC_010473.1 UDP-galactopyranose mutase, FAD/NAD(P)-binding 2197361 glf 6059501 glf Escherichia coli str. K-12 substr. DH10B UDP-galactopyranose mutase, FAD/NAD(P)-binding YP_001730986.1 2196258 R 316385 CDS YP_001730987.1 170081667 6059502 complement(2197369..2198616) 1 NC_010473.1 polisoprenol-linked O-antigen transporter 2198616 rfbX 6059502 rfbX Escherichia coli str. K-12 substr. DH10B polisoprenol-linked O-antigen transporter YP_001730987.1 2197369 R 316385 CDS YP_001730988.1 170081668 6059503 complement(2198613..2199170) 1 NC_010473.1 dTDP-4-deoxyrhamnose-3,5-epimerase 2199170 rfbC 6059503 rfbC Escherichia coli str. K-12 substr. DH10B dTDP-4-deoxyrhamnose-3,5-epimerase YP_001730988.1 2198613 R 316385 CDS YP_001730989.1 170081669 6059507 complement(2199170..2200051) 1 NC_010473.1 glucose-1-phosphate thymidylyltransferase 2200051 rfbA 6059507 rfbA Escherichia coli str. K-12 substr. DH10B glucose-1-phosphate thymidylyltransferase YP_001730989.1 2199170 R 316385 CDS YP_001730990.1 170081670 6059508 complement(2200109..2201008) 1 NC_010473.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase 2201008 rfbD 6059508 rfbD Escherichia coli str. K-12 substr. DH10B dTDP-4-dehydrorhamnose reductase YP_001730990.1 2200109 R 316385 CDS YP_001730991.1 170081671 6059518 complement(2201008..2202093) 1 NC_010473.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase 2202093 rfbB 6059518 rfbB Escherichia coli str. K-12 substr. DH10B dTDP-glucose-4,6-dehydratase YP_001730991.1 2201008 R 316385 CDS YP_001730992.1 170081672 6059521 complement(2202466..2203359) 1 NC_010473.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 2203359 galF 6059521 galF Escherichia coli str. K-12 substr. DH10B UTP--glucose-1-phosphate uridylyltransferase subunit GalF YP_001730992.1 2202466 R 316385 CDS YP_001730993.1 170081673 6059522 complement(2203534..2204928) 1 NC_010473.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein 2204928 wcaM 6059522 wcaM Escherichia coli str. K-12 substr. DH10B putative colanic acid biosynthesis protein YP_001730993.1 2203534 R 316385 CDS YP_001730994.1 170081674 6059525 complement(2204939..2206159) 1 NC_010473.1 glycosyl transferase family protein 2206159 wcaL 6059525 wcaL Escherichia coli str. K-12 substr. DH10B glycosyl transferase family protein YP_001730994.1 2204939 R 316385 CDS YP_001730995.1 170081675 6059528 complement(2206156..2207436) 1 NC_010473.1 putative pyruvyl transferase 2207436 wcaK 6059528 wcaK Escherichia coli str. K-12 substr. DH10B putative pyruvyl transferase YP_001730995.1 2206156 R 316385 CDS YP_001730996.1 170081676 6059540 complement(2207712..2209190) 1 NC_010473.1 colanic acid exporter 2209190 wzxC 6059540 wzxC Escherichia coli str. K-12 substr. DH10B colanic acid exporter YP_001730996.1 2207712 R 316385 CDS YP_001730997.1 170081677 6059544 complement(2209192..2210586) 1 NC_010473.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase 2210586 wcaJ 6059544 wcaJ Escherichia coli str. K-12 substr. DH10B putative UDP-glucose lipid carrier transferase YP_001730997.1 2209192 R 316385 CDS YP_001730998.1 170081678 6059546 complement(2210641..2212011) 1 NC_010473.1 phosphomannomutase 2212011 cpsG 6059546 cpsG Escherichia coli str. K-12 substr. DH10B phosphomannomutase YP_001730998.1 2210641 R 316385 CDS YP_001730999.1 170081679 6059558 complement(2212116..2213552) 1 NC_010473.1 mannose-1-phosphate guanyltransferase 2213552 cpsB 6059558 cpsB Escherichia coli str. K-12 substr. DH10B mannose-1-phosphate guanyltransferase YP_001730999.1 2212116 R 316385 CDS YP_001731000.1 170081680 6059563 complement(2213555..2214778) 1 NC_010473.1 putative glycosyl transferase 2214778 wcaI 6059563 wcaI Escherichia coli str. K-12 substr. DH10B putative glycosyl transferase YP_001731000.1 2213555 R 316385 CDS YP_001731001.1 170081681 6059566 complement(2214775..2215254) 1 NC_010473.1 GDP-mannose mannosyl hydrolase 2215254 nudD 6059566 nudD Escherichia coli str. K-12 substr. DH10B GDP-mannose mannosyl hydrolase YP_001731001.1 2214775 R 316385 CDS YP_001731002.1 170081682 6059576 complement(2215257..2216222) 1 NC_010473.1 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase 2216222 fcl 6059576 fcl Escherichia coli str. K-12 substr. DH10B bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase YP_001731002.1 2215257 R 316385 CDS YP_001731003.1 170081683 6059580 complement(2216225..2217346) 1 NC_010473.1 GDP-D-mannose dehydratase 2217346 gmd 6059580 gmd Escherichia coli str. K-12 substr. DH10B GDP-D-mannose dehydratase YP_001731003.1 2216225 R 316385 CDS YP_001731004.1 170081684 6059586 complement(2217372..2217920) 1 NC_010473.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF 2217920 wcaF 6059586 wcaF Escherichia coli str. K-12 substr. DH10B putative colanic acid biosynthesis acetyltransferase WcaF YP_001731004.1 2217372 R 316385 CDS YP_001731005.1 170081685 6059589 complement(2217936..2218682) 1 NC_010473.1 putative glycosyl transferase 2218682 wcaE 6059589 wcaE Escherichia coli str. K-12 substr. DH10B putative glycosyl transferase YP_001731005.1 2217936 R 316385 CDS YP_001731006.1 170081686 6059591 complement(2218693..2219910) 1 NC_010473.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 2219910 wcaD 6059591 wcaD Escherichia coli str. K-12 substr. DH10B putative colanic acid biosynthesis protein YP_001731006.1 2218693 R 316385 CDS YP_001731007.1 170081687 6059594 complement(2219885..2221102) 1 NC_010473.1 putative glycosyl transferase 2221102 wcaC 6059594 wcaC Escherichia coli str. K-12 substr. DH10B putative glycosyl transferase YP_001731007.1 2219885 R 316385 CDS YP_001731008.1 170081688 6059599 complement(2221099..2221587) 1 NC_010473.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB 2221587 wcaB 6059599 wcaB Escherichia coli str. K-12 substr. DH10B putative colanic acid biosynthesis acetyltransferase WcaB YP_001731008.1 2221099 R 316385 CDS YP_001731009.1 170081689 6059614 complement(2221590..2222429) 1 NC_010473.1 putative glycosyl transferase 2222429 wcaA 6059614 wcaA Escherichia coli str. K-12 substr. DH10B putative glycosyl transferase YP_001731009.1 2221590 R 316385 CDS YP_001731010.1 170081690 6059620 complement(2222522..2224684) 1 NC_010473.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2224684 wzc 6059620 wzc Escherichia coli str. K-12 substr. DH10B tyrosine kinase YP_001731010.1 2222522 R 316385 CDS YP_001731011.1 170081691 6059622 complement(2224687..2225130) 1 NC_010473.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2225130 wzb 6059622 wzb Escherichia coli str. K-12 substr. DH10B tyrosine phosphatase YP_001731011.1 2224687 R 316385 CDS YP_001731012.1 170081692 6059631 complement(2225136..2226275) 1 NC_010473.1 lipoprotein required for capsular polysaccharide translocation through the outer membrane 2226275 wza 6059631 wza Escherichia coli str. K-12 substr. DH10B lipoprotein required for capsular polysaccharide translocation through the outer membrane YP_001731012.1 2225136 R 316385 CDS YP_001731013.1 170081693 6059638 2226934..2228517 1 NC_010473.1 fused membrane protein; membrane protein 2228517 yegH 6059638 yegH Escherichia coli str. K-12 substr. DH10B fused membrane protein; membrane protein YP_001731013.1 2226934 D 316385 CDS YP_001731014.1 170081694 6059644 complement(2228791..2230644) 1 NC_010473.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein 2230644 asmA 6059644 asmA Escherichia coli str. K-12 substr. DH10B putative assembly protein YP_001731014.1 2228791 R 316385 CDS YP_001731015.1 170081695 6059647 complement(2230666..2231247) 1 NC_010473.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2231247 dcd 6059647 dcd Escherichia coli str. K-12 substr. DH10B deoxycytidine triphosphate deaminase YP_001731015.1 2230666 R 316385 CDS YP_001731016.1 170081696 6059654 complement(2231339..2231980) 1 NC_010473.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2231980 udk 6059654 udk Escherichia coli str. K-12 substr. DH10B uridine kinase YP_001731016.1 2231339 R 316385 CDS YP_001731017.1 170081697 6059656 2232298..2235615 1 NC_010473.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein 2235615 yegE 6059656 yegE Escherichia coli str. K-12 substr. DH10B putative sensor protein YP_001731017.1 2232298 D 316385 CDS YP_001731018.1 170081698 6059665 complement(2235724..2236572) 1 NC_010473.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 2236572 alkA 6059665 alkA Escherichia coli str. K-12 substr. DH10B 3-methyladenine DNA glycosylase YP_001731018.1 2235724 R 316385 CDS YP_001731019.1 170081699 6059680 2236706..2238058 1 NC_010473.1 putative chaperone 2238058 yegD 6059680 yegD Escherichia coli str. K-12 substr. DH10B putative chaperone YP_001731019.1 2236706 D 316385 CDS YP_001731020.1 170081700 6059682 complement(2238071..2240017) 1 NC_010473.1 hypothetical protein 2240017 yegI 6059682 yegI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731020.1 2238071 R 316385 CDS YP_001731021.1 170081701 6059694 2240217..2240678 1 NC_010473.1 hypothetical protein 2240678 yegJ 6059694 yegJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731021.1 2240217 D 316385 CDS YP_001731022.1 170081702 6059710 complement(2240743..2241504) 1 NC_010473.1 hypothetical protein 2241504 yegK 6059710 yegK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731022.1 2240743 R 316385 CDS YP_001731023.1 170081703 6059711 complement(2241501..2242160) 1 NC_010473.1 hypothetical protein 2242160 yegL 6059711 yegL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731023.1 2241501 R 316385 CDS YP_001731024.1 170081704 6060091 2243048..2244295 1 NC_010473.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2244295 mdtA 6060091 mdtA Escherichia coli str. K-12 substr. DH10B multidrug efflux system subunit MdtA YP_001731024.1 2243048 D 316385 CDS YP_001731025.1 170081705 6059722 2244295..2247417 1 NC_010473.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2247417 mdtB 6059722 mdtB Escherichia coli str. K-12 substr. DH10B multidrug efflux system subunit MdtB YP_001731025.1 2244295 D 316385 CDS YP_001731026.1 170081706 6059728 2247418..2250495 1 NC_010473.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2250495 mdtC 6059728 mdtC Escherichia coli str. K-12 substr. DH10B multidrug efflux system subunit MdtC YP_001731026.1 2247418 D 316385 CDS YP_001731027.1 170081707 6059734 2250496..2251911 1 NC_010473.1 multidrug efflux system protein MdtE 2251911 mdtD 6059734 mdtD Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein MdtE YP_001731027.1 2250496 D 316385 CDS YP_001731028.1 170081708 6059735 2251908..2253311 1 NC_010473.1 signal transduction histidine-protein kinase BaeS 2253311 baeS 6059735 baeS Escherichia coli str. K-12 substr. DH10B signal transduction histidine-protein kinase BaeS YP_001731028.1 2251908 D 316385 CDS YP_001731029.1 170081709 6059737 2253308..2254030 1 NC_010473.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2254030 baeR 6059737 baeR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator BaeR YP_001731029.1 2253308 D 316385 CDS YP_001731030.1 170081710 6059738 2254221..2254553 1 NC_010473.1 hypothetical protein 2254553 yegP 6059738 yegP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731030.1 2254221 D 316385 CDS YP_001731031.1 170081711 6059745 2254700..2256061 1 NC_010473.1 peptidase 2256061 yegQ 6059745 yegQ Escherichia coli str. K-12 substr. DH10B peptidase YP_001731031.1 2254700 D 316385 CDS YP_001731032.1 170081712 6058567 complement(2256334..2256552) 1 NC_010473.1 in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 2256552 ogrK 6058567 ogrK Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731032.1 2256334 R 316385 CDS YP_001731033.1 170081713 6059757 complement(2257021..2257338) 1 NC_010473.1 hypothetical protein 2257338 yegR 6059757 yegR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731033.1 2257021 R 316385 CDS YP_001731034.1 170081714 6059769 2257744..2258643 1 NC_010473.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2258643 yegS 6059769 yegS Escherichia coli str. K-12 substr. DH10B lipid kinase YP_001731034.1 2257744 D 316385 CDS YP_001731035.1 170081715 6059781 2259259..2259567 1 NC_010473.1 IS3 element protein InsE 2259567 insE-5 6059781 insE-5 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsE YP_001731035.1 2259259 D 316385 CDS YP_001731036.1 170081716 6059801 2259564..2260430 1 NC_010473.1 IS3 element protein InsF 2260430 insF-5 6059801 insF-5 Escherichia coli str. K-12 substr. DH10B IS3 element protein InsF YP_001731036.1 2259564 D 316385 CDS YP_001731037.1 170081717 6059804 complement(2260865..2261905) 1 NC_010473.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2261905 gatD 6059804 gatD Escherichia coli str. K-12 substr. DH10B galactitol-1-phosphate dehydrogenase YP_001731037.1 2260865 R 316385 CDS YP_001731038.1 170081718 6059807 complement(2261953..2263308) 1 NC_010473.1 PTS system galactitol-specific transporter subunit IIC 2263308 gatC 6059807 gatC Escherichia coli str. K-12 substr. DH10B PTS system galactitol-specific transporter subunit IIC YP_001731038.1 2261953 R 316385 CDS YP_001731039.1 170081719 6059810 complement(2263312..2263596) 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2263596 gatB 6059810 gatB Escherichia coli str. K-12 substr. DH10B PTS system galactitol-specific transporter subunit IIB YP_001731039.1 2263312 R 316385 CDS YP_001731040.1 170081720 6059816 complement(2263627..2264079) 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2264079 gatA 6059816 gatA Escherichia coli str. K-12 substr. DH10B PTS system galactitol-specific transporter subunit IIA YP_001731040.1 2263627 R 316385 CDS YP_001731041.1 170081721 6059825 complement(2265380..2266234) 1 NC_010473.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2266234 gatY 6059825 gatY Escherichia coli str. K-12 substr. DH10B tagatose-bisphosphate aldolase YP_001731041.1 2265380 R 316385 CDS YP_001731042.1 170081722 6059826 complement(2266542..2267594) 1 NC_010473.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2267594 fbaB 6059826 fbaB Escherichia coli str. K-12 substr. DH10B fructose-bisphosphate aldolase YP_001731042.1 2266542 R 316385 CDS YP_001731043.1 170081723 6059833 2267851..2269128 1 NC_010473.1 nucleoside transporter 2269128 yegT 6059833 yegT Escherichia coli str. K-12 substr. DH10B nucleoside transporter YP_001731043.1 2267851 D 316385 CDS YP_001731044.1 170081724 6059852 2269125..2270129 1 NC_010473.1 hydrolase 2270129 yegU 6059852 yegU Escherichia coli str. K-12 substr. DH10B hydrolase YP_001731044.1 2269125 D 316385 CDS YP_001731045.1 170081725 6059853 2270126..2271091 1 NC_010473.1 kinase 2271091 yegV 6059853 yegV Escherichia coli str. K-12 substr. DH10B kinase YP_001731045.1 2270126 D 316385 CDS YP_001731046.1 170081726 6059860 complement(2271065..2271811) 1 NC_010473.1 DNA-binding transcriptional regulator 2271811 yegW 6059860 yegW Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731046.1 2271065 R 316385 CDS YP_001731047.1 170081727 6058923 complement(2271863..2272681) 1 NC_010473.1 hydrolase 2272681 yegX 6058923 yegX Escherichia coli str. K-12 substr. DH10B hydrolase YP_001731047.1 2271863 R 316385 CDS YP_001731048.1 170081728 6059863 complement(2272746..2273546) 1 NC_010473.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2273546 thiD 6059863 thiD Escherichia coli str. K-12 substr. DH10B phosphomethylpyrimidine kinase YP_001731048.1 2272746 R 316385 CDS YP_001731049.1 170081729 6059864 complement(2273543..2274331) 1 NC_010473.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2274331 thiM 6059864 thiM Escherichia coli str. K-12 substr. DH10B hydroxyethylthiazole kinase YP_001731049.1 2273543 R 316385 CDS YP_001731050.1 170081730 6059871 complement(2274554..2274826) 1 NC_010473.1 transcriptional repressor of rcnA 2274826 rcnR 6059871 rcnR Escherichia coli str. K-12 substr. DH10B transcriptional repressor of rcnA YP_001731050.1 2274554 R 316385 CDS YP_001731051.1 170081731 6060390 2274947..2275771 1 NC_010473.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2275771 yohM 6060390 yohM Escherichia coli str. K-12 substr. DH10B nickel/cobalt efflux protein RcnA YP_001731051.1 2274947 D 316385 CDS YP_001731052.1 170081732 6059876 2275990..2276328 1 NC_010473.1 hypothetical protein 2276328 yohN 6059876 yohN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731052.1 2275990 D 316385 CDS YP_001731053.1 170081733 6058766 complement(2277460..2279940) 1 NC_010473.1 outer membrane protein 2279940 yehB 6058766 yehB Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001731053.1 2277460 R 316385 CDS YP_001731054.1 170081734 6059885 complement(2279956..2280675) 1 NC_010473.1 periplasmic pilin chaperone 2280675 yehC 6059885 yehC Escherichia coli str. K-12 substr. DH10B periplasmic pilin chaperone YP_001731054.1 2279956 R 316385 CDS YP_001731055.1 170081735 6059887 complement(2280710..2281252) 1 NC_010473.1 fimbrial-like adhesin protein 2281252 yehD 6059887 yehD Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001731055.1 2280710 R 316385 CDS YP_001731056.1 170081736 6059911 complement(2281545..2281826) 1 NC_010473.1 hypothetical protein 2281826 yehE 6059911 yehE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731056.1 2281545 R 316385 CDS YP_001731057.1 170081737 6059913 complement(2282089..2283198) 1 NC_010473.1 putative ATPase 2283198 mrp 6059913 mrp Escherichia coli str. K-12 substr. DH10B putative ATPase YP_001731057.1 2282089 R 316385 CDS YP_001731058.1 170081738 6059122 2283330..2285363 1 NC_010473.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2285363 metG 6059122 metG Escherichia coli str. K-12 substr. DH10B methionyl-tRNA synthetase YP_001731058.1 2283330 D 316385 CDS YP_001731059.1 170081739 6059101 2289309..2292941 1 NC_010473.1 hypothetical protein 2292941 yehI 6059101 yehI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731059.1 2289309 D 316385 CDS YP_001731060.1 170081740 6059954 2293002..2293319 1 NC_010473.1 hypothetical protein 2293319 yehK 6059954 yehK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731060.1 2293002 D 316385 CDS YP_001731061.1 170081741 6058749 2293626..2294714 1 NC_010473.1 ABC transporter ATP-binding protein 2294714 yehL 6058749 yehL Escherichia coli str. K-12 substr. DH10B ABC transporter ATP-binding protein YP_001731061.1 2293626 D 316385 CDS YP_001731062.1 170081742 6058750 2294725..2297004 1 NC_010473.1 hypothetical protein 2297004 yehM 6058750 yehM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731062.1 2294725 D 316385 CDS YP_001731063.1 170081743 6058751 2296997..2298133 1 NC_010473.1 hypothetical protein 2298133 yehP 6058751 yehP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731063.1 2296997 D 316385 CDS YP_001731064.1 170081744 6058756 2298130..2299974 1 NC_010473.1 hypothetical protein 2299974 yehQ 6058756 yehQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731064.1 2298130 D 316385 CDS YP_001731065.1 170081745 6058757 2300255..2300716 1 NC_010473.1 hypothetical protein 2300716 yehR 6058757 yehR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731065.1 2300255 D 316385 CDS YP_001731066.1 170081746 6058758 complement(2300756..2301226) 1 NC_010473.1 hypothetical protein 2301226 yehS 6058758 yehS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731066.1 2300756 R 316385 CDS YP_001731067.1 170081747 6058763 complement(2301273..2301992) 1 NC_010473.1 unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT 2301992 yehT 6058763 yehT Escherichia coli str. K-12 substr. DH10B putative two-component response-regulatory protein YehT YP_001731067.1 2301273 R 316385 CDS YP_001731068.1 170081748 6058769 complement(2301989..2303674) 1 NC_010473.1 sensory kinase in two-component system with YehT 2303674 yehU 6058769 yehU Escherichia coli str. K-12 substr. DH10B sensory kinase in two-component system with YehT YP_001731068.1 2301989 R 316385 CDS YP_001731069.1 170081749 6058771 2303896..2304627 1 NC_010473.1 DNA-binding transcriptional regulator 2304627 mlrA 6058771 mlrA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731069.1 2303896 D 316385 CDS YP_001731070.1 170081750 6059956 2304687..2304794 1 NC_010473.1 hypothetical protein 2304794 yohO 6059956 yohO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731070.1 2304687 D 316385 CDS YP_001731071.1 170081751 6059994 complement(2304775..2305506) 1 NC_010473.1 ABC transporter membrane protein 2305506 yehW 6059994 yehW Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001731071.1 2304775 R 316385 CDS YP_001731072.1 170081752 6060008 complement(2305511..2306437) 1 NC_010473.1 ABC transporter ATP-binding protein 2306437 yehX 6060008 yehX Escherichia coli str. K-12 substr. DH10B ABC transporter ATP-binding protein YP_001731072.1 2305511 R 316385 CDS YP_001731073.1 170081753 6060014 complement(2306430..2307587) 1 NC_010473.1 ABC transporter membrane protein 2307587 yehY 6060014 yehY Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001731073.1 2306430 R 316385 CDS YP_001731074.1 170081754 6060025 complement(2307594..2308511) 1 NC_010473.1 ABC transporter substrate-binding protein 2308511 yehZ 6060025 yehZ Escherichia coli str. K-12 substr. DH10B ABC transporter substrate-binding protein YP_001731074.1 2307594 R 316385 CDS YP_001731075.1 170081755 6060026 complement(2308722..2311019) 1 NC_010473.1 beta-D-glucoside glucohydrolase, periplasmic 2311019 bglX 6060026 bglX Escherichia coli str. K-12 substr. DH10B beta-D-glucoside glucohydrolase, periplasmic YP_001731075.1 2308722 R 316385 CDS YP_001731076.1 170081756 6060037 2311215..2312930 1 NC_010473.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2312930 dld 6060037 dld Escherichia coli str. K-12 substr. DH10B D-lactate dehydrogenase YP_001731076.1 2311215 D 316385 CDS YP_001731077.1 170081757 6060044 complement(2312968..2313900) 1 NC_010473.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2313900 pbpG 6060044 pbpG Escherichia coli str. K-12 substr. DH10B D-alanyl-D-alanine endopeptidase YP_001731077.1 2312968 R 316385 CDS YP_001731078.1 170081758 6059074 complement(2314074..2314661) 1 NC_010473.1 inner membrane protein 2314661 yohC 6059074 yohC Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731078.1 2314074 R 316385 CDS YP_001731079.1 170081759 6060056 2314831..2315409 1 NC_010473.1 inner membrane protein 2315409 yohD 6060056 yohD Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731079.1 2314831 D 316385 CDS YP_001731080.1 170081760 6060073 complement(2315539..2316300) 1 NC_010473.1 acetoin dehydrogenase 2316300 yohF 6060073 yohF Escherichia coli str. K-12 substr. DH10B acetoin dehydrogenase YP_001731080.1 2315539 R 316385 CDS YP_001731081.1 170081761 6060126 complement(2316353..2317441) 1 NC_010473.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2317441 yohG 6060126 yohG Escherichia coli str. K-12 substr. DH10B multidrug resistance outer membrane protein MdtQ YP_001731081.1 2316353 R 316385 CDS YP_001731082.1 170081762 6060136 complement(2317579..2317716) 1 NC_010473.1 hypothetical protein 2317716 yohH 6060136 yohH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731082.1 2317579 R 316385 CDS YP_001731083.1 170081763 6058700 complement(2318468..2319415) 1 NC_010473.1 tRNA-dihydrouridine synthase C 2319415 dusC 6058700 dusC Escherichia coli str. K-12 substr. DH10B tRNA-dihydrouridine synthase C YP_001731083.1 2318468 R 316385 CDS YP_001731084.1 170081764 6060157 2319654..2320052 1 NC_010473.1 hypothetical protein 2320052 yohJ 6060157 yohJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731084.1 2319654 D 316385 CDS YP_001731085.1 170081765 6058640 2320049..2320744 1 NC_010473.1 hypothetical protein 2320744 yohK 6058640 yohK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731085.1 2320049 D 316385 CDS YP_001731086.1 170081766 6060167 2320874..2321758 1 NC_010473.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2321758 cdd 6060167 cdd Escherichia coli str. K-12 substr. DH10B cytidine deaminase YP_001731086.1 2320874 D 316385 CDS YP_001731087.1 170081767 6060176 2321908..2322627 1 NC_010473.1 hypothetical protein 2322627 sanA 6060176 sanA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731087.1 2321908 D 316385 CDS YP_001731088.1 170081768 6060204 2322630..2322869 1 NC_010473.1 inner membrane protein 2322869 yeiS 6060204 yeiS Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731088.1 2322630 D 316385 CDS YP_001731089.1 170081769 6060223 2323063..2324301 1 NC_010473.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 2324301 yeiT 6060223 yeiT Escherichia coli str. K-12 substr. DH10B putative oxidoreductase YP_001731089.1 2323063 D 316385 CDS YP_001731090.1 170081770 6060230 2324295..2325530 1 NC_010473.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2325530 yeiA 6060230 yeiA Escherichia coli str. K-12 substr. DH10B dihydropyrimidine dehydrogenase YP_001731090.1 2324295 D 316385 CDS YP_001731091.1 170081771 6060271 complement(2325773..2326783) 1 NC_010473.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 2326783 mglC 6060271 mglC Escherichia coli str. K-12 substr. DH10B beta-methylgalactoside transporter inner membrane protein YP_001731091.1 2325773 R 316385 CDS YP_001731092.1 170081772 6058678 complement(2328361..2329359) 1 NC_010473.1 methyl-galactoside ABC transporter periplasmic substrate-binding protein 2329359 mglB 6058678 mglB Escherichia coli str. K-12 substr. DH10B methyl-galactoside ABC transporter periplasmic substrate-binding protein YP_001731092.1 2328361 R 316385 CDS YP_001731093.1 170081773 6060290 complement(2329639..2330679) 1 NC_010473.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2330679 galS 6060290 galS Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator GalS YP_001731093.1 2329639 R 316385 CDS YP_001731094.1 170081774 6060309 complement(2330821..2331978) 1 NC_010473.1 hypothetical protein 2331978 yeiB 6060309 yeiB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731094.1 2330821 R 316385 CDS YP_001731095.1 170081775 6060311 complement(2331995..2332663) 1 NC_010473.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2332663 folE 6060311 folE Escherichia coli str. K-12 substr. DH10B GTP cyclohydrolase I YP_001731095.1 2331995 R 316385 CDS YP_001731096.1 170081776 6058679 2332921..2333757 1 NC_010473.1 esterase 2333757 yeiG 6058679 yeiG Escherichia coli str. K-12 substr. DH10B esterase YP_001731096.1 2332921 D 316385 CDS YP_001731097.1 170081777 6060317 complement(2333789..2335780) 1 NC_010473.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2335780 cirA 6060317 cirA Escherichia coli str. K-12 substr. DH10B colicin I receptor YP_001731097.1 2333789 R 316385 CDS YP_001731098.1 170081778 6060332 complement(2336074..2337543) 1 NC_010473.1 lysine transporter 2337543 lysP 6060332 lysP Escherichia coli str. K-12 substr. DH10B lysine transporter YP_001731098.1 2336074 R 316385 CDS YP_001731099.1 170081779 6060333 complement(2337748..2338629) 1 NC_010473.1 putative DNA-binding transcriptional regulator 2338629 yeiE 6060333 yeiE Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001731099.1 2337748 R 316385 CDS YP_001731100.1 170081780 6060349 2338728..2339777 1 NC_010473.1 inner membrane protein 2339777 yeiH 6060349 yeiH Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731100.1 2338728 D 316385 CDS YP_001731101.1 170081781 6060359 2339851..2340708 1 NC_010473.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2340708 nfo 6060359 nfo Escherichia coli str. K-12 substr. DH10B endonuclease IV YP_001731101.1 2339851 D 316385 CDS YP_001731102.1 170081782 6060378 2340711..2341799 1 NC_010473.1 hypothetical protein 2341799 yeiI 6060378 yeiI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731102.1 2340711 D 316385 CDS YP_001731103.1 170081783 6060386 complement(2341906..2343156) 1 NC_010473.1 nucleoside transporter 2343156 yeiJ 6060386 yeiJ Escherichia coli str. K-12 substr. DH10B nucleoside transporter YP_001731103.1 2341906 R 316385 CDS YP_001731104.1 170081784 6060412 complement(2343256..2344197) 1 NC_010473.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2344197 rihB 6060412 rihB Escherichia coli str. K-12 substr. DH10B ribonucleoside hydrolase 2 YP_001731104.1 2343256 R 316385 CDS YP_001731105.1 170081785 6060415 2344366..2345025 1 NC_010473.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2345025 yeiL 6060415 yeiL Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator YeiL YP_001731105.1 2344366 D 316385 CDS YP_001731106.1 170081786 6060430 complement(2345096..2346346) 1 NC_010473.1 nucleoside transporter 2346346 yeiM 6060430 yeiM Escherichia coli str. K-12 substr. DH10B nucleoside transporter YP_001731106.1 2345096 R 316385 CDS YP_001731107.1 170081787 6060453 complement(2346440..2347378) 1 NC_010473.1 hypothetical protein 2347378 yeiN 6060453 yeiN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731107.1 2346440 R 316385 CDS YP_001731108.1 170081788 6060455 complement(2347366..2348307) 1 NC_010473.1 hypothetical protein 2348307 yeiC 6060455 yeiC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731108.1 2347366 R 316385 CDS YP_001731109.1 170081789 6060473 complement(2348730..2350421) 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 2350421 fruA 6060473 fruA Escherichia coli str. K-12 substr. DH10B PTS system fructose-specific transporter subunit IIBC YP_001731109.1 2348730 R 316385 CDS YP_001731110.1 170081790 6060477 complement(2350438..2351376) 1 NC_010473.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2351376 fruK 6060477 fruK Escherichia coli str. K-12 substr. DH10B 1-phosphofructokinase YP_001731110.1 2350438 R 316385 CDS YP_001731111.1 170081791 6060520 2352873..2354054 1 NC_010473.1 lactose/glucose efflux system 2354054 setB 6060520 setB Escherichia coli str. K-12 substr. DH10B lactose/glucose efflux system YP_001731111.1 2352873 D 316385 CDS YP_001731112.1 170081792 6060521 complement(2354051..2354305) 1 NC_010473.1 hypothetical protein 2354305 yeiW 6060521 yeiW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731112.1 2354051 R 316385 CDS YP_001731113.1 170081793 6060523 2354460..2355032 1 NC_010473.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2355032 yeiP 6060523 yeiP Escherichia coli str. K-12 substr. DH10B elongation factor P YP_001731113.1 2354460 D 316385 CDS YP_001731114.1 170081794 6060525 2355255..2356721 1 NC_010473.1 dehydrogenase, NAD-dependent 2356721 yeiQ 6060525 yeiQ Escherichia coli str. K-12 substr. DH10B dehydrogenase, NAD-dependent YP_001731114.1 2355255 D 316385 CDS YP_001731115.1 170081795 6060541 2356839..2357825 1 NC_010473.1 hypothetical protein 2357825 yeiR 6060541 yeiR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731115.1 2356839 D 316385 CDS YP_001731116.1 170081796 6060585 2357864..2358577 1 NC_010473.1 undecaprenyl pyrophosphate phosphatase 2358577 yeiU 6060585 yeiU Escherichia coli str. K-12 substr. DH10B undecaprenyl pyrophosphate phosphatase YP_001731116.1 2357864 D 316385 CDS YP_001731117.1 170081797 6060596 2358989..2359555 1 NC_010473.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein 2359555 spr 6060596 spr Escherichia coli str. K-12 substr. DH10B putative outer membrane lipoprotein YP_001731117.1 2358989 D 316385 CDS YP_001731118.1 170081798 6060610 2359736..2361292 1 NC_010473.1 hypothetical protein 2361292 rtn 6060610 rtn Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731118.1 2359736 D 316385 CDS YP_001731119.1 170081799 6060613 2361374..2363188 1 NC_010473.1 oligopeptide ABC transporter periplasmic-binding protein 2363188 yejA 6060613 yejA Escherichia coli str. K-12 substr. DH10B oligopeptide ABC transporter periplasmic-binding protein YP_001731119.1 2361374 D 316385 CDS YP_001731120.1 170081800 6060645 2363189..2364283 1 NC_010473.1 oligopeptide ABC transporter membrane protein 2364283 yejB 6060645 yejB Escherichia coli str. K-12 substr. DH10B oligopeptide ABC transporter membrane protein YP_001731120.1 2363189 D 316385 CDS YP_001731121.1 170081801 6060655 2364283..2365308 1 NC_010473.1 oligopeptide ABC transporter membrane protein 2365308 yejE 6060655 yejE Escherichia coli str. K-12 substr. DH10B oligopeptide ABC transporter membrane protein YP_001731121.1 2364283 D 316385 CDS YP_001731122.1 170081802 6060666 2365310..2366899 1 NC_010473.1 fused oligopeptide transporter subunits of ABC superfamilly: ATP-binding components 2366899 yejF 6060666 yejF Escherichia coli str. K-12 substr. DH10B fused oligopeptide transporter subunits of ABC superfamilly: ATP-binding components YP_001731122.1 2365310 D 316385 CDS YP_001731123.1 170081803 6060669 complement(2366903..2367247) 1 NC_010473.1 hypothetical protein 2367247 yejG 6060669 yejG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731123.1 2366903 R 316385 CDS YP_001731124.1 170081804 6060673 complement(2367580..2368770) 1 NC_010473.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 2368770 bcr 6060673 bcr Escherichia coli str. K-12 substr. DH10B bicyclomycin/multidrug efflux system protein YP_001731124.1 2367580 R 316385 CDS YP_001731125.1 170081805 6060694 complement(2368798..2369493) 1 NC_010473.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2369493 rsuA 6060694 rsuA Escherichia coli str. K-12 substr. DH10B 16S rRNA pseudouridylate synthase A YP_001731125.1 2368798 R 316385 CDS YP_001731126.1 170081806 6060718 2369642..2371402 1 NC_010473.1 ATP-dependet helicase 2371402 yejH 6060718 yejH Escherichia coli str. K-12 substr. DH10B ATP-dependet helicase YP_001731126.1 2369642 D 316385 CDS YP_001731127.1 170081807 6060723 2371527..2371811 1 NC_010473.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2371811 rplY 6060723 rplY Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L25 YP_001731127.1 2371527 D 316385 CDS YP_001731128.1 170081808 6060733 complement(2371950..2372957) 1 NC_010473.1 nucleoid-associated protein NdpA 2372957 yejK 6060733 yejK Escherichia coli str. K-12 substr. DH10B nucleoid-associated protein NdpA YP_001731128.1 2371950 R 316385 CDS YP_001731129.1 170081809 6060740 2373139..2373366 1 NC_010473.1 hypothetical protein 2373366 yejL 6060740 yejL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731129.1 2373139 D 316385 CDS YP_001731130.1 170081810 6060742 2373386..2375146 1 NC_010473.1 hydrolase, inner membrane 2375146 yejM 6060742 yejM Escherichia coli str. K-12 substr. DH10B hydrolase, inner membrane YP_001731130.1 2373386 D 316385 CDS YP_001731131.1 170081811 6058422 complement(2375400..2377910) 1 NC_010473.1 autotransporter outer membrane protein 2377910 yejO 6058422 yejO Escherichia coli str. K-12 substr. DH10B autotransporter outer membrane protein YP_001731131.1 2375400 R 316385 CDS YP_001731132.1 170081812 6060752 complement(2378075..2379091) 1 NC_010473.1 IS5 transposase and trans-activator 2379091 insH-8 6060752 insH-8 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001731132.1 2378075 R 316385 CDS YP_001731133.1 170081813 6060767 2379510..2380157 1 NC_010473.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2380157 narP 6060767 narP Escherichia coli str. K-12 substr. DH10B transcriptional regulator NarP YP_001731133.1 2379510 D 316385 CDS YP_001731134.1 170081814 6060778 complement(2380368..2381420) 1 NC_010473.1 heme lyase, CcmH subunit 2381420 ccmH 6060778 ccmH Escherichia coli str. K-12 substr. DH10B heme lyase, CcmH subunit YP_001731134.1 2380368 R 316385 CDS YP_001731135.1 170081815 6060152 complement(2381417..2381974) 1 NC_010473.1 periplasmic thioredoxin of cytochrome c-type biogenesis 2381974 ccmG 6060152 ccmG Escherichia coli str. K-12 substr. DH10B periplasmic thioredoxin of cytochrome c-type biogenesis YP_001731135.1 2381417 R 316385 CDS YP_001731136.1 170081816 6060486 complement(2381971..2383914) 1 NC_010473.1 heme lyase, CcmF subunit 2383914 ccmF 6060486 ccmF Escherichia coli str. K-12 substr. DH10B heme lyase, CcmF subunit YP_001731136.1 2381971 R 316385 CDS YP_001731137.1 170081817 6058616 complement(2383911..2384390) 1 NC_010473.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2384390 ccmE 6058616 ccmE Escherichia coli str. K-12 substr. DH10B cytochrome c-type biogenesis protein CcmE YP_001731137.1 2383911 R 316385 CDS YP_001731138.1 170081818 6058673 complement(2384387..2384596) 1 NC_010473.1 cytochrome c biogenesis protein 2384596 ccmD 6058673 ccmD Escherichia coli str. K-12 substr. DH10B cytochrome c biogenesis protein YP_001731138.1 2384387 R 316385 CDS YP_001731139.1 170081819 6058723 complement(2384593..2385330) 1 NC_010473.1 heme ABC transporter membrane protein 2385330 ccmC 6058723 ccmC Escherichia coli str. K-12 substr. DH10B heme ABC transporter membrane protein YP_001731139.1 2384593 R 316385 CDS YP_001731140.1 170081820 6058859 complement(2385372..2386034) 1 NC_010473.1 heme ABC transporter membrane protein 2386034 ccmB 6058859 ccmB Escherichia coli str. K-12 substr. DH10B heme ABC transporter membrane protein YP_001731140.1 2385372 R 316385 CDS YP_001731141.1 170081821 6059046 complement(2386031..2386654) 1 NC_010473.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2386654 ccmA 6059046 ccmA Escherichia coli str. K-12 substr. DH10B cytochrome c biogenesis protein CcmA YP_001731141.1 2386031 R 316385 CDS YP_001731142.1 170081822 6059094 complement(2386667..2387269) 1 NC_010473.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2387269 napC 6059094 napC Escherichia coli str. K-12 substr. DH10B cytochrome c-type protein NapC YP_001731142.1 2386667 R 316385 CDS YP_001731143.1 170081823 6059474 complement(2387279..2387728) 1 NC_010473.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2387728 napB 6059474 napB Escherichia coli str. K-12 substr. DH10B citrate reductase cytochrome c-type subunit YP_001731143.1 2387279 R 316385 CDS YP_001731144.1 170081824 6059828 complement(2387725..2388588) 1 NC_010473.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2388588 napH 6059828 napH Escherichia coli str. K-12 substr. DH10B quinol dehydrogenase membrane component YP_001731144.1 2387725 R 316385 CDS YP_001731145.1 170081825 6060067 complement(2388575..2389270) 1 NC_010473.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2389270 napG 6060067 napG Escherichia coli str. K-12 substr. DH10B quinol dehydrogenase periplasmic component YP_001731145.1 2388575 R 316385 CDS YP_001731146.1 170081826 6060165 complement(2389277..2391763) 1 NC_010473.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2391763 napA 6060165 napA Escherichia coli str. K-12 substr. DH10B nitrate reductase catalytic subunit YP_001731146.1 2389277 R 316385 CDS YP_001731147.1 170081827 6058819 complement(2391760..2392023) 1 NC_010473.1 assembly protein for periplasmic nitrate reductase 2392023 napD 6058819 napD Escherichia coli str. K-12 substr. DH10B assembly protein for periplasmic nitrate reductase YP_001731147.1 2391760 R 316385 CDS YP_001731148.1 170081828 6058807 complement(2392013..2392507) 1 NC_010473.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 2392507 napF 6058807 napF Escherichia coli str. K-12 substr. DH10B ferredoxin-type protein YP_001731148.1 2392013 R 316385 CDS YP_001731149.1 170081829 6059505 2392915..2393403 1 NC_010473.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2393403 eco 6059505 eco Escherichia coli str. K-12 substr. DH10B ecotin YP_001731149.1 2392915 D 316385 CDS YP_001731150.1 170081830 6059847 complement(2394118..2395764) 1 NC_010473.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2395764 mqo 6059847 mqo Escherichia coli str. K-12 substr. DH10B malate:quinone oxidoreductase YP_001731150.1 2394118 R 316385 CDS YP_001731151.1 170081831 6058824 complement(2395982..2397625) 1 NC_010473.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component 2397625 yojI 6058824 yojI Escherichia coli str. K-12 substr. DH10B multidrug transporter membrane protein/ATP-binding component YP_001731151.1 2395982 R 316385 CDS YP_001731152.1 170081832 6059097 complement(2397701..2398351) 1 NC_010473.1 oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions 2398351 alkB 6059097 alkB Escherichia coli str. K-12 substr. DH10B oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions YP_001731152.1 2397701 R 316385 CDS YP_001731153.1 170081833 6059404 complement(2398351..2399415) 1 NC_010473.1 fused DNA-binding transcriptional dual regulator; O6-methylguanine-DNA methyltransferase 2399415 ada 6059404 ada Escherichia coli str. K-12 substr. DH10B fused DNA-binding transcriptional dual regulator; O6-methylguanine-DNA methyltransferase YP_001731153.1 2398351 R 316385 CDS YP_001731154.1 170081834 6059590 complement(2399489..2400544) 1 NC_010473.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2400544 yojL 6059590 yojL Escherichia coli str. K-12 substr. DH10B thiamine biosynthesis lipoprotein ApbE YP_001731154.1 2399489 R 316385 CDS YP_001731155.1 170081835 6059669 complement(2400656..2401759) 1 NC_010473.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 2401759 ompC 6059669 ompC Escherichia coli str. K-12 substr. DH10B outer membrane porin protein C YP_001731155.1 2400656 R 316385 CDS YP_001731156.1 170081836 6058542 2402498..2405170 1 NC_010473.1 phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2405170 rcsD 6058542 rcsD Escherichia coli str. K-12 substr. DH10B phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_001731156.1 2402498 D 316385 CDS YP_001731157.1 170081837 6059899 2405187..2405837 1 NC_010473.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2405837 rcsB 6059899 rcsB Escherichia coli str. K-12 substr. DH10B transcriptional regulator RcsB YP_001731157.1 2405187 D 316385 CDS YP_001731158.1 170081838 6059883 complement(2406037..2408886) 1 NC_010473.1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2408886 rcsC 6059883 rcsC Escherichia coli str. K-12 substr. DH10B hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_001731158.1 2406037 R 316385 CDS YP_001731159.1 170081839 6059829 2409053..2410879 1 NC_010473.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2410879 atoS 6059829 atoS Escherichia coli str. K-12 substr. DH10B sensory histidine kinase AtoS YP_001731159.1 2409053 D 316385 CDS YP_001731160.1 170081840 6059881 2410876..2412261 1 NC_010473.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2412261 atoC 6059881 atoC Escherichia coli str. K-12 substr. DH10B acetoacetate metabolism regulatory protein AtoC YP_001731160.1 2410876 D 316385 CDS YP_001731161.1 170081841 6059872 2412457..2413119 1 NC_010473.1 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2413119 atoD 6059872 atoD Escherichia coli str. K-12 substr. DH10B acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_001731161.1 2412457 D 316385 CDS YP_001731162.1 170081842 6059895 2413119..2413769 1 NC_010473.1 acetyl-CoA:acetoacetyl-CoA transferase, beta subunit 2413769 atoA 6059895 atoA Escherichia coli str. K-12 substr. DH10B acetyl-CoA:acetoacetyl-CoA transferase, beta subunit YP_001731162.1 2413119 D 316385 CDS YP_001731163.1 170081843 6059890 2413766..2415088 1 NC_010473.1 short chain fatty acid transporter 2415088 atoE 6059890 atoE Escherichia coli str. K-12 substr. DH10B short chain fatty acid transporter YP_001731163.1 2413766 D 316385 CDS YP_001731164.1 170081844 6062408 2415119..2416303 1 NC_010473.1 acetyl-CoA acetyltransferase 2416303 atoB 6062408 atoB Escherichia coli str. K-12 substr. DH10B acetyl-CoA acetyltransferase YP_001731164.1 2415119 D 316385 CDS YP_001731165.1 170081845 6060178 complement(2416377..2417153) 1 NC_010473.1 hypothetical protein 2417153 yfaP 6060178 yfaP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731165.1 2416377 R 316385 CDS YP_001731166.1 170081846 6058084 complement(2417158..2418807) 1 NC_010473.1 hypothetical protein 2418807 yfaQ 6058084 yfaQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731166.1 2417158 R 316385 CDS YP_001731167.1 170081847 6058113 complement(2423346..2423969) 1 NC_010473.1 hypothetical protein 2423969 yfaT 6058113 yfaT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731167.1 2423346 R 316385 CDS YP_001731168.1 170081848 6058120 complement(2423966..2425654) 1 NC_010473.1 hypothetical protein 2425654 yfaA 6058120 yfaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731168.1 2423966 R 316385 CDS YP_001731169.1 170081849 6058121 complement(2425803..2428430) 1 NC_010473.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2428430 gyrA 6058121 gyrA Escherichia coli str. K-12 substr. DH10B DNA gyrase subunit A YP_001731169.1 2425803 R 316385 CDS YP_001731170.1 170081850 6058142 2428577..2429299 1 NC_010473.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2429299 ubiG 6058142 ubiG Escherichia coli str. K-12 substr. DH10B 3-demethylubiquinone-9 3-methyltransferase YP_001731170.1 2428577 D 316385 CDS YP_001731171.1 170081851 6058150 complement(2429427..2433179) 1 NC_010473.1 adhesin 2433179 yfaL 6058150 yfaL Escherichia coli str. K-12 substr. DH10B adhesin YP_001731171.1 2429427 R 316385 CDS YP_001731172.1 170081852 6058156 2433875..2436160 1 NC_010473.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2436160 nrdA 6058156 nrdA Escherichia coli str. K-12 substr. DH10B ribonucleotide-diphosphate reductase subunit alpha YP_001731172.1 2433875 D 316385 CDS YP_001731173.1 170081853 6058191 2436394..2437524 1 NC_010473.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2437524 nrdB 6058191 nrdB Escherichia coli str. K-12 substr. DH10B ribonucleotide-diphosphate reductase subunit beta YP_001731173.1 2436394 D 316385 CDS YP_001731174.1 170081854 6058192 2437524..2437778 1 NC_010473.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2437778 yfaE 6058192 yfaE Escherichia coli str. K-12 substr. DH10B 2Fe-2S ferredoxin YP_001731174.1 2437524 D 316385 CDS YP_001731175.1 170081855 6058230 complement(2437832..2438482) 1 NC_010473.1 hypothetical protein 2438482 inaA 6058230 inaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731175.1 2437832 R 316385 CDS YP_001731176.1 170081856 6058234 2438697..2438903 1 NC_010473.1 hypothetical protein 2438903 yfaH 6058234 yfaH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731176.1 2438697 D 316385 CDS YP_001731177.1 170081857 6058255 complement(2438945..2440021) 1 NC_010473.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2440021 glpQ 6058255 glpQ Escherichia coli str. K-12 substr. DH10B glycerophosphodiester phosphodiesterase YP_001731177.1 2438945 R 316385 CDS YP_001731178.1 170081858 6058297 complement(2440026..2441384) 1 NC_010473.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2441384 glpT 6058297 glpT Escherichia coli str. K-12 substr. DH10B sn-glycerol-3-phosphate transporter YP_001731178.1 2440026 R 316385 CDS YP_001731179.1 170081859 6058301 2441657..2443285 1 NC_010473.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2443285 glpA 6058301 glpA Escherichia coli str. K-12 substr. DH10B sn-glycerol-3-phosphate dehydrogenase subunit A YP_001731179.1 2441657 D 316385 CDS YP_001731180.1 170081860 6058319 2443275..2444534 1 NC_010473.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2444534 glpB 6058319 glpB Escherichia coli str. K-12 substr. DH10B anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_001731180.1 2443275 D 316385 CDS YP_001731181.1 170081861 6058330 2444531..2445721 1 NC_010473.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2445721 glpC 6058330 glpC Escherichia coli str. K-12 substr. DH10B sn-glycerol-3-phosphate dehydrogenase subunit C YP_001731181.1 2444531 D 316385 CDS YP_001731182.1 170081862 6058346 2445914..2446813 1 NC_010473.1 hypothetical protein 2446813 yfaD 6058346 yfaD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731182.1 2445914 D 316385 CDS YP_001731183.1 170081863 6058381 complement(2447052..2447855) 1 NC_010473.1 putative aldolase 2447855 yfaU 6058381 yfaU Escherichia coli str. K-12 substr. DH10B putative aldolase YP_001731183.1 2447052 R 316385 CDS YP_001731184.1 170081864 6058382 complement(2447873..2449162) 1 NC_010473.1 transporter 2449162 yfaV 6058382 yfaV Escherichia coli str. K-12 substr. DH10B transporter YP_001731184.1 2447873 R 316385 CDS YP_001731185.1 170081865 6058390 complement(2449219..2450436) 1 NC_010473.1 enolase 2450436 yfaW 6058390 yfaW Escherichia coli str. K-12 substr. DH10B enolase YP_001731185.1 2449219 R 316385 CDS YP_001731186.1 170081866 6058397 complement(2450439..2451221) 1 NC_010473.1 DNA-binding transcriptional regulator 2451221 yfaX 6058397 yfaX Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731186.1 2450439 R 316385 CDS YP_001731187.1 170081867 6058455 complement(2451441..2452643) 1 NC_010473.1 competence damage-inducible protein A 2452643 yfaY 6058455 yfaY Escherichia coli str. K-12 substr. DH10B competence damage-inducible protein A YP_001731187.1 2451441 R 316385 CDS YP_001731188.1 170081868 6058476 complement(2452743..2453285) 1 NC_010473.1 outer membrane porin protein 2453285 yfaZ 6058476 yfaZ Escherichia coli str. K-12 substr. DH10B outer membrane porin protein YP_001731188.1 2452743 R 316385 CDS YP_001731189.1 170081869 6059295 2453564..2453989 1 NC_010473.1 NUDIX hydrolase 2453989 yfaO 6059295 yfaO Escherichia coli str. K-12 substr. DH10B NUDIX hydrolase YP_001731189.1 2453564 D 316385 CDS YP_001731190.1 170081870 6058500 complement(2454028..2454630) 1 NC_010473.1 hypothetical protein 2454630 ais 6058500 ais Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731190.1 2454028 R 316385 CDS YP_001731191.1 170081871 6058503 2454938..2456077 1 NC_010473.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2456077 arnB 6058503 arnB Escherichia coli str. K-12 substr. DH10B UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_001731191.1 2454938 D 316385 CDS YP_001731192.1 170081872 6058534 2456081..2457049 1 NC_010473.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2457049 arnC 6058534 arnC Escherichia coli str. K-12 substr. DH10B undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_001731192.1 2456081 D 316385 CDS YP_001731193.1 170081873 6058544 2457049..2459031 1 NC_010473.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2459031 arnA 6058544 arnA Escherichia coli str. K-12 substr. DH10B bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_001731193.1 2457049 D 316385 CDS YP_001731194.1 170081874 6058560 2459028..2459918 1 NC_010473.1 hypothetical protein 2459918 yfbH 6058560 yfbH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731194.1 2459028 D 316385 CDS YP_001731195.1 170081875 6058563 2459918..2461570 1 NC_010473.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2461570 arnT 6058563 arnT Escherichia coli str. K-12 substr. DH10B 4-amino-4-deoxy-L-arabinose transferase YP_001731195.1 2459918 D 316385 CDS YP_001731196.1 170081876 6058580 2461567..2461902 1 NC_010473.1 hypothetical protein 2461902 yfbW 6058580 yfbW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731196.1 2461567 D 316385 CDS YP_001731197.1 170081877 6058589 2461902..2462288 1 NC_010473.1 hypothetical protein 2462288 yfbJ 6058589 yfbJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731197.1 2461902 D 316385 CDS YP_001731198.1 170081878 6058599 complement(2462282..2462548) 1 NC_010473.1 polymyxin resistance protein B 2462548 pmrD 6058599 pmrD Escherichia coli str. K-12 substr. DH10B polymyxin resistance protein B YP_001731198.1 2462282 R 316385 CDS YP_001731199.1 170081879 6058607 complement(2462658..2464013) 1 NC_010473.1 O-succinylbenzoic acid--CoA ligase 2464013 menE 6058607 menE Escherichia coli str. K-12 substr. DH10B O-succinylbenzoic acid--CoA ligase YP_001731199.1 2462658 R 316385 CDS YP_001731200.1 170081880 6058613 complement(2464010..2464972) 1 NC_010473.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2464972 menC 6058613 menC Escherichia coli str. K-12 substr. DH10B O-succinylbenzoate synthase YP_001731200.1 2464010 R 316385 CDS YP_001731201.1 170081881 6058627 complement(2464972..2465829) 1 NC_010473.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2465829 menB 6058627 menB Escherichia coli str. K-12 substr. DH10B naphthoate synthase YP_001731201.1 2464972 R 316385 CDS YP_001731202.1 170081882 6058643 complement(2465844..2466602) 1 NC_010473.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 2466602 yfbB 6058643 yfbB Escherichia coli str. K-12 substr. DH10B acyl-CoA thioester hydrolase YfbB YP_001731202.1 2465844 R 316385 CDS YP_001731203.1 170081883 6058661 complement(2466599..2468269) 1 NC_010473.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2468269 menD 6058661 menD Escherichia coli str. K-12 substr. DH10B 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_001731203.1 2466599 R 316385 CDS YP_001731204.1 170081884 6058685 complement(2468358..2469653) 1 NC_010473.1 isochorismate synthase 2 2469653 menF 6058685 menF Escherichia coli str. K-12 substr. DH10B isochorismate synthase 2 YP_001731204.1 2468358 R 316385 CDS YP_001731205.1 170081885 6058687 complement(2469732..2470037) 1 NC_010473.1 hypothetical protein 2470037 elaB 6058687 elaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731205.1 2469732 R 316385 CDS YP_001731206.1 170081886 6058688 complement(2470092..2470553) 1 NC_010473.1 hypothetical protein 2470553 elaA 6058688 elaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731206.1 2470092 R 316385 CDS YP_001731207.1 170081887 6058695 2472500..2473711 1 NC_010473.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2473711 elaD 6058695 elaD Escherichia coli str. K-12 substr. DH10B deubiquitinase YP_001731207.1 2472500 D 316385 CDS YP_001731208.1 170081888 6058715 2475647..2476618 1 NC_010473.1 peptidase 2476618 yfbL 6058715 yfbL Escherichia coli str. K-12 substr. DH10B peptidase YP_001731208.1 2475647 D 316385 CDS YP_001731209.1 170081889 6058716 2476721..2477224 1 NC_010473.1 hypothetical protein 2477224 yfbM 6058716 yfbM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731209.1 2476721 D 316385 CDS YP_001731210.1 170081890 6058746 complement(2477497..2478213) 1 NC_010473.1 hypothetical protein 2478213 yfbN 6058746 yfbN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731210.1 2477497 R 316385 CDS YP_001731211.1 170081891 6058752 2478368..2478844 1 NC_010473.1 hypothetical protein 2478844 yfbO 6058752 yfbO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731211.1 2478368 D 316385 CDS YP_001731212.1 170081892 6058755 2478900..2479751 1 NC_010473.1 hypothetical protein 2479751 yfbP 6058755 yfbP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731212.1 2478900 D 316385 CDS YP_001731213.1 170081893 6058782 complement(2479835..2481112) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2481112 nuoN 6058782 nuoN Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit N YP_001731213.1 2479835 R 316385 CDS YP_001731214.1 170081894 6058794 complement(2481299..2482828) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2482828 nuoM 6058794 nuoM Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit M YP_001731214.1 2481299 R 316385 CDS YP_001731215.1 170081895 6058832 complement(2482992..2484833) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2484833 nuoL 6058832 nuoL Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit L YP_001731215.1 2482992 R 316385 CDS YP_001731216.1 170081896 6058833 complement(2484830..2485132) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2485132 nuoK 6058833 nuoK Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit K YP_001731216.1 2484830 R 316385 CDS YP_001731217.1 170081897 6058844 complement(2485129..2485683) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2485683 nuoJ 6058844 nuoJ Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit J YP_001731217.1 2485129 R 316385 CDS YP_001731218.1 170081898 6058845 complement(2485695..2486237) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2486237 nuoI 6058845 nuoI Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit I YP_001731218.1 2485695 R 316385 CDS YP_001731219.1 170081899 6058868 complement(2486252..2487229) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2487229 nuoH 6058868 nuoH Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit H YP_001731219.1 2486252 R 316385 CDS YP_001731220.1 170081900 6058872 complement(2487226..2489958) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2489958 nuoG 6058872 nuoG Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit G YP_001731220.1 2487226 R 316385 CDS YP_001731221.1 170081901 6058884 complement(2490005..2491342) 1 NC_010473.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2491342 nuoF 6058884 nuoF Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase I subunit F YP_001731221.1 2490005 R 316385 CDS YP_001731222.1 170081902 6058886 complement(2491339..2491839) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2491839 nuoE 6058886 nuoE Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit E YP_001731222.1 2491339 R 316385 CDS YP_001731223.1 170081903 6058903 complement(2491842..2493644) 1 NC_010473.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2493644 nuoC 6058903 nuoC Escherichia coli str. K-12 substr. DH10B bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_001731223.1 2491842 R 316385 CDS YP_001731224.1 170081904 6058908 complement(2493738..2494400) 1 NC_010473.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2494400 nuoB 6058908 nuoB Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit B YP_001731224.1 2493738 R 316385 CDS YP_001731225.1 170081905 6058909 complement(2494416..2494859) 1 NC_010473.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2494859 nuoA 6058909 nuoA Escherichia coli str. K-12 substr. DH10B NADH dehydrogenase subunit A YP_001731225.1 2494416 R 316385 CDS YP_001731226.1 170081906 6059316 complement(2495490..2496428) 1 NC_010473.1 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes 2496428 lrhA 6059316 lrhA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes YP_001731226.1 2495490 R 316385 CDS YP_001731227.1 170081907 6058932 2497348..2498565 1 NC_010473.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2498565 yfbQ 6058932 yfbQ Escherichia coli str. K-12 substr. DH10B aminotransferase AlaT YP_001731227.1 2497348 D 316385 CDS YP_001731228.1 170081908 6058934 2498649..2499248 1 NC_010473.1 hypothetical protein 2499248 yfbR 6058934 yfbR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731228.1 2498649 D 316385 CDS YP_001731229.1 170081909 6058939 complement(2501226..2501876) 1 NC_010473.1 putative phosphatase 2501876 yfbT 6058939 yfbT Escherichia coli str. K-12 substr. DH10B putative phosphatase YP_001731229.1 2501226 R 316385 CDS YP_001731230.1 170081910 6058941 complement(2501887..2502381) 1 NC_010473.1 hypothetical protein 2502381 yfbU 6058941 yfbU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731230.1 2501887 R 316385 CDS YP_001731231.1 170081911 6058948 complement(2502464..2502919) 1 NC_010473.1 hypothetical protein 2502919 yfbV 6058948 yfbV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731231.1 2502464 R 316385 CDS YP_001731232.1 170081912 6058957 2503257..2504459 1 NC_010473.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2504459 ackA 6058957 ackA Escherichia coli str. K-12 substr. DH10B acetate kinase YP_001731232.1 2503257 D 316385 CDS YP_001731233.1 170081913 6058958 2504534..2506678 1 NC_010473.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2506678 pta 6058958 pta Escherichia coli str. K-12 substr. DH10B phosphate acetyltransferase YP_001731233.1 2504534 D 316385 CDS YP_001731234.1 170081914 6058959 2506868..2508388 1 NC_010473.1 hypothetical protein 2508388 yfcC 6058959 yfcC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731234.1 2506868 D 316385 CDS YP_001731235.1 170081915 6058967 complement(2508421..2508963) 1 NC_010473.1 NUDIX hydrolase 2508963 yfcD 6058967 yfcD Escherichia coli str. K-12 substr. DH10B NUDIX hydrolase YP_001731235.1 2508421 R 316385 CDS YP_001731236.1 170081916 6058985 complement(2509021..2509575) 1 NC_010473.1 phosphodiesterase 2509575 yfcE 6058985 yfcE Escherichia coli str. K-12 substr. DH10B phosphodiesterase YP_001731236.1 2509021 R 316385 CDS YP_001731237.1 170081917 6058987 complement(2509628..2510272) 1 NC_010473.1 hypothetical protein 2510272 yfcF 6058987 yfcF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731237.1 2509628 R 316385 CDS YP_001731238.1 170081918 6059003 2510408..2511055 1 NC_010473.1 glutathione S-transferase 2511055 yfcG 6059003 yfcG Escherichia coli str. K-12 substr. DH10B glutathione S-transferase YP_001731238.1 2510408 D 316385 CDS YP_001731239.1 170081919 6059004 2511112..2511474 1 NC_010473.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2511474 folX 6059004 folX Escherichia coli str. K-12 substr. DH10B D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_001731239.1 2511112 D 316385 CDS YP_001731240.1 170081920 6059011 2511495..2512388 1 NC_010473.1 hypothetical protein 2512388 yfcH 6059011 yfcH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731240.1 2511495 D 316385 CDS YP_001731241.1 170081921 6059012 complement(2512436..2513326) 1 NC_010473.1 putative transposase 2513326 yfcI 6059012 yfcI Escherichia coli str. K-12 substr. DH10B putative transposase YP_001731241.1 2512436 R 316385 CDS YP_001731242.1 170081922 6059023 complement(2513523..2514296) 1 NC_010473.1 histidine/lysine/arginine/ornithine transporter subunit 2514296 hisP 6059023 hisP Escherichia coli str. K-12 substr. DH10B histidine/lysine/arginine/ornithine transporter subunit YP_001731242.1 2513523 R 316385 CDS YP_001731243.1 170081923 6059027 complement(2514304..2515020) 1 NC_010473.1 histidine/lysine/arginine/ornithine ABC transporter membrane protein 2515020 hisM 6059027 hisM Escherichia coli str. K-12 substr. DH10B histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_001731243.1 2514304 R 316385 CDS YP_001731244.1 170081924 6059035 complement(2515017..2515703) 1 NC_010473.1 histidine/lysine/arginine/ornithine ABC transporter membrane protein 2515703 hisQ 6059035 hisQ Escherichia coli str. K-12 substr. DH10B histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_001731244.1 2515017 R 316385 CDS YP_001731245.1 170081925 6059041 complement(2515793..2516575) 1 NC_010473.1 histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein 2516575 hisJ 6059041 hisJ Escherichia coli str. K-12 substr. DH10B histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_001731245.1 2515793 R 316385 CDS YP_001731246.1 170081926 6059042 complement(2516796..2517578) 1 NC_010473.1 lysine/arginine/ornithine ABC transporter periplasmic-binding protein 2517578 argT 6059042 argT Escherichia coli str. K-12 substr. DH10B lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_001731246.1 2516796 R 316385 CDS YP_001731247.1 170081927 6059050 complement(2517844..2518413) 1 NC_010473.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2518413 ubiX 6059050 ubiX Escherichia coli str. K-12 substr. DH10B 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001731247.1 2517844 R 316385 CDS YP_001731248.1 170081928 6059052 complement(2518508..2520025) 1 NC_010473.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2520025 purF 6059052 purF Escherichia coli str. K-12 substr. DH10B amidophosphoribosyltransferase YP_001731248.1 2518508 R 316385 CDS YP_001731249.1 170081929 6059056 complement(2520062..2520550) 1 NC_010473.1 membrane protein required for colicin V production; colicin V production protein 2520550 cvpA 6059056 cvpA Escherichia coli str. K-12 substr. DH10B colicin V production protein YP_001731249.1 2520062 R 316385 CDS YP_001731250.1 170081930 6059073 complement(2520809..2521471) 1 NC_010473.1 hypothetical protein 2521471 dedD 6059073 dedD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731250.1 2520809 R 316385 CDS YP_001731251.1 170081931 6059080 complement(2521461..2522729) 1 NC_010473.1 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2522729 folC 6059080 folC Escherichia coli str. K-12 substr. DH10B bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_001731251.1 2521461 R 316385 CDS YP_001731252.1 170081932 6059083 complement(2522799..2523713) 1 NC_010473.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2523713 accD 6059083 accD Escherichia coli str. K-12 substr. DH10B acetyl-CoA carboxylase subunit beta YP_001731252.1 2522799 R 316385 CDS YP_001731253.1 170081933 6059125 complement(2523869..2524528) 1 NC_010473.1 hypothetical protein 2524528 dedA 6059125 dedA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731253.1 2523869 R 316385 CDS YP_001731254.1 170081934 6059152 complement(2524611..2525423) 1 NC_010473.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2525423 truA 6059152 truA Escherichia coli str. K-12 substr. DH10B tRNA pseudouridine synthase A YP_001731254.1 2524611 R 316385 CDS YP_001731255.1 170081935 6059153 complement(2525423..2526436) 1 NC_010473.1 putative semialdehyde dehydrogenase 2526436 usg 6059153 usg Escherichia coli str. K-12 substr. DH10B putative semialdehyde dehydrogenase YP_001731255.1 2525423 R 316385 CDS YP_001731256.1 170081936 6059173 complement(2526502..2527638) 1 NC_010473.1 erythronate-4-phosphate dehydrogenase 2527638 pdxB 6059173 pdxB Escherichia coli str. K-12 substr. DH10B erythronate-4-phosphate dehydrogenase YP_001731256.1 2526502 R 316385 CDS YP_001731257.1 170081937 6059181 2527737..2528732 1 NC_010473.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2528732 flk 6059181 flk Escherichia coli str. K-12 substr. DH10B flagella biosynthesis regulator YP_001731257.1 2527737 D 316385 CDS YP_001731258.1 170081938 6059200 complement(2528729..2529907) 1 NC_010473.1 hypothetical protein 2529907 yfcJ 6059200 yfcJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731258.1 2528729 R 316385 CDS YP_001731259.1 170081939 6059208 complement(2530172..2531392) 1 NC_010473.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2531392 fabB 6059208 fabB Escherichia coli str. K-12 substr. DH10B 3-oxoacyl-ACP synthase YP_001731259.1 2530172 R 316385 CDS YP_001731260.1 170081940 6059219 2531551..2533557 1 NC_010473.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2533557 mnmC 6059219 mnmC Escherichia coli str. K-12 substr. DH10B 5-methylaminomethyl-2-thiouridine methyltransferase YP_001731260.1 2531551 D 316385 CDS YP_001731261.1 170081941 6059220 complement(2533678..2533956) 1 NC_010473.1 hypothetical protein 2533956 yfcL 6059220 yfcL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731261.1 2533678 R 316385 CDS YP_001731262.1 170081942 6059231 complement(2533990..2534538) 1 NC_010473.1 hypothetical protein 2534538 yfcM 6059231 yfcM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731262.1 2533990 R 316385 CDS YP_001731263.1 170081943 6059256 complement(2534538..2535347) 1 NC_010473.1 hypothetical protein 2535347 yfcA 6059256 yfcA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731263.1 2534538 R 316385 CDS YP_001731264.1 170081944 6059273 complement(2535347..2536171) 1 NC_010473.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2536171 mepA 6059273 mepA Escherichia coli str. K-12 substr. DH10B penicillin-insensitive murein endopeptidase YP_001731264.1 2535347 R 316385 CDS YP_001731265.1 170081945 6059277 complement(2536175..2537260) 1 NC_010473.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2537260 aroC 6059277 aroC Escherichia coli str. K-12 substr. DH10B chorismate synthase YP_001731265.1 2536175 R 316385 CDS YP_001731266.1 170081946 6059289 complement(2537295..2538227) 1 NC_010473.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2538227 prmB 6059289 prmB Escherichia coli str. K-12 substr. DH10B N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001731266.1 2537295 R 316385 CDS YP_001731267.1 170081947 6059294 2538393..2538944 1 NC_010473.1 hypothetical protein 2538944 yfcN 6059294 yfcN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731267.1 2538393 D 316385 CDS YP_001731268.1 170081948 6059842 complement(2539015..2539836) 1 NC_010473.1 hypothetical protein 2539836 yfcO 6059842 yfcO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731268.1 2539015 R 316385 CDS YP_001731269.1 170081949 6059461 complement(2539838..2540377) 1 NC_010473.1 fimbrial-like adhesin protein 2540377 yfcP 6059461 yfcP Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001731269.1 2539838 R 316385 CDS YP_001731270.1 170081950 6059701 complement(2540374..2540862) 1 NC_010473.1 fimbrial-like adhesin protein 2540862 yfcQ 6059701 yfcQ Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001731270.1 2540374 R 316385 CDS YP_001731271.1 170081951 6059755 complement(2540859..2541371) 1 NC_010473.1 fimbrial-like adhesin protein 2541371 yfcR 6059755 yfcR Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001731271.1 2540859 R 316385 CDS YP_001731272.1 170081952 6059794 complement(2541371..2542123) 1 NC_010473.1 periplasmic pilus chaperone 2542123 yfcS 6059794 yfcS Escherichia coli str. K-12 substr. DH10B periplasmic pilus chaperone YP_001731272.1 2541371 R 316385 CDS YP_001731273.1 170081953 6059867 complement(2542143..2543039) 1 NC_010473.1 outer membrane export usher protein 2543039 yfcT 6059867 yfcT Escherichia coli str. K-12 substr. DH10B outer membrane export usher protein YP_001731273.1 2542143 R 316385 CDS YP_001731274.1 170081954 6059880 complement(2543052..2544788) 1 NC_010473.1 export usher protein 2544788 yfcU 6059880 yfcU Escherichia coli str. K-12 substr. DH10B export usher protein YP_001731274.1 2543052 R 316385 CDS YP_001731275.1 170081955 6059886 complement(2544870..2545433) 1 NC_010473.1 fimbrial-like adhesin protein 2545433 yfcV 6059886 yfcV Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001731275.1 2544870 R 316385 CDS YP_001731276.1 170081956 6059891 complement(2546114..2546599) 1 NC_010473.1 phosphohistidine phosphatase 2546599 sixA 6059891 sixA Escherichia coli str. K-12 substr. DH10B phosphohistidine phosphatase YP_001731276.1 2546114 R 316385 CDS YP_001731277.1 170081957 6059893 complement(2546802..2548946) 1 NC_010473.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2548946 fadJ 6059893 fadJ Escherichia coli str. K-12 substr. DH10B multifunctional fatty acid oxidation complex subunit alpha YP_001731277.1 2546802 R 316385 CDS YP_001731278.1 170081958 6059897 complement(2548946..2550256) 1 NC_010473.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2550256 fadI 6059897 fadI Escherichia coli str. K-12 substr. DH10B 3-ketoacyl-CoA thiolase YP_001731278.1 2548946 R 316385 CDS YP_001731279.1 170081959 6059903 complement(2550437..2550721) 1 NC_010473.1 hypothetical protein 2550721 yfcZ 6059903 yfcZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731279.1 2550437 R 316385 CDS YP_001731280.1 170081960 6059914 2551087..2552433 1 NC_010473.1 long-chain fatty acid outer membrane transporter 2552433 fadL 6059914 fadL Escherichia coli str. K-12 substr. DH10B long-chain fatty acid outer membrane transporter YP_001731280.1 2551087 D 316385 CDS YP_001731281.1 170081961 6059915 2552799..2553857 1 NC_010473.1 hypothetical protein 2553857 yfdF 6059915 yfdF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731281.1 2552799 D 316385 CDS YP_001731282.1 170081962 6059415 complement(2554039..2554794) 1 NC_010473.1 lipoprotein 2554794 vacJ 6059415 vacJ Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001731282.1 2554039 R 316385 CDS YP_001731283.1 170081963 6059916 2555088..2556020 1 NC_010473.1 inner membrane protein 2556020 yfdC 6059916 yfdC Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731283.1 2555088 D 316385 CDS YP_001731284.1 170081964 6062425 2556332..2557489 1 NC_010473.1 CPS-53 (KpLE1) prophage; prophage CPS-53 integrase 2557489 intS 6062425 intS Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; prophage CPS-53 integrase YP_001731284.1 2556332 D 316385 CDS YP_001731285.1 170081965 6059920 2557642..2558004 1 NC_010473.1 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) 2558004 yfdG 6059920 yfdG Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) YP_001731285.1 2557642 D 316385 CDS YP_001731286.1 170081966 6059921 2558001..2558921 1 NC_010473.1 CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase 2558921 yfdH 6059921 yfdH Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase YP_001731286.1 2558001 D 316385 CDS YP_001731287.1 170081967 6059923 2558918..2560249 1 NC_010473.1 CPS-53 (KpLE1) prophage; inner membrane protein 2560249 yfdI 6059923 yfdI Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; inner membrane protein YP_001731287.1 2558918 D 316385 CDS YP_001731288.1 170081968 6059196 complement(2560864..2561304) 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2561304 yfdK 6059196 yfdK Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731288.1 2560864 R 316385 CDS YP_001731289.1 170081969 6059925 complement(2561331..2561849) 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2561849 yfdL 6059925 yfdL Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731289.1 2561331 R 316385 CDS YP_001731290.1 170081970 6059926 complement(2561899..2562174) 1 NC_010473.1 CPS-53 (KpLE1) prophage; methyltransferase 2562174 yfdM 6059926 yfdM Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; methyltransferase YP_001731290.1 2561899 R 316385 CDS YP_001731291.1 170081971 6059927 complement(2562174..2562668) 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2562668 yfdN 6059927 yfdN Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731291.1 2562174 R 316385 CDS YP_001731292.1 170081972 6059928 complement(2562665..2563033) 1 NC_010473.1 CPS-53 (KpLE1) prophage; defective phage replication protein O 2563033 yfdO 6059928 yfdO Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; defective phage replication protein O YP_001731292.1 2562665 R 316385 CDS YP_001731293.1 170081973 6059930 2563307..2563753 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2563753 yfdP 6059930 yfdP Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731293.1 2563307 D 316385 CDS YP_001731294.1 170081974 6059934 2563819..2564643 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2564643 yfdQ 6059934 yfdQ Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731294.1 2563819 D 316385 CDS YP_001731295.1 170081975 6059935 2564771..2565307 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2565307 yfdR 6059935 yfdR Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731295.1 2564771 D 316385 CDS YP_001731296.1 170081976 6059937 2565298..2565660 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2565660 yfdS 6059937 yfdS Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731296.1 2565298 D 316385 CDS YP_001731297.1 170081977 6059938 2565660..2565965 1 NC_010473.1 CPS-53 (KpLE1) prophage; hypothetical protein 2565965 yfdT 6059938 yfdT Escherichia coli str. K-12 substr. DH10B CPS-53 (KpLE1) prophage; hypothetical protein YP_001731297.1 2565660 D 316385 CDS YP_001731298.1 170081978 6059939 2565881..2566021 1 NC_010473.1 hypothetical protein 2566021 ypdJ 6059939 ypdJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731298.1 2565881 D 316385 CDS YP_001731299.1 170081979 6059941 2566097..2566297 1 NC_010473.1 response regulator inhibitor for tor operon 2566297 torI 6059941 torI Escherichia coli str. K-12 substr. DH10B response regulator inhibitor for tor operon YP_001731299.1 2566097 D 316385 CDS YP_001731300.1 170081980 6059942 complement(2566481..2567416) 1 NC_010473.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 2567416 dsdC 6059942 dsdC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator DsdC YP_001731300.1 2566481 R 316385 CDS YP_001731301.1 170081981 6059943 2567634..2568971 1 NC_010473.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2568971 dsdX 6059943 dsdX Escherichia coli str. K-12 substr. DH10B permease DsdX YP_001731301.1 2567634 D 316385 CDS YP_001731302.1 170081982 6059944 2568989..2570317 1 NC_010473.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2570317 dsdA 6059944 dsdA Escherichia coli str. K-12 substr. DH10B D-serine dehydratase YP_001731302.1 2568989 D 316385 CDS YP_001731303.1 170081983 6059945 complement(2570425..2571963) 1 NC_010473.1 multidrug efflux system 2571963 emrY 6059945 emrY Escherichia coli str. K-12 substr. DH10B multidrug efflux system YP_001731303.1 2570425 R 316385 CDS YP_001731304.1 170081984 6059946 complement(2571963..2573126) 1 NC_010473.1 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component 2573126 emrK 6059946 emrK Escherichia coli str. K-12 substr. DH10B EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component YP_001731304.1 2571963 R 316385 CDS YP_001731305.1 170081985 6059949 2573542..2574156 1 NC_010473.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2574156 evgA 6059949 evgA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator EvgA YP_001731305.1 2573542 D 316385 CDS YP_001731306.1 170081986 6059950 complement(2577810..2578955) 1 NC_010473.1 hypothetical protein 2578955 yfdE 6059950 yfdE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731306.1 2577810 R 316385 CDS YP_001731307.1 170081987 6059951 complement(2579029..2579973) 1 NC_010473.1 member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV 2579973 yfdV 6059951 yfdV Escherichia coli str. K-12 substr. DH10B putative transporter YfdV YP_001731307.1 2579029 R 316385 CDS YP_001731308.1 170081988 6059952 complement(2580043..2581737) 1 NC_010473.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase 2581737 oxc 6059952 oxc Escherichia coli str. K-12 substr. DH10B putative oxalyl-CoA decarboxylase YP_001731308.1 2580043 R 316385 CDS YP_001731309.1 170081989 6059953 complement(2581791..2583041) 1 NC_010473.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2583041 frc 6059953 frc Escherichia coli str. K-12 substr. DH10B formyl-coenzyme A transferase YP_001731309.1 2581791 R 316385 CDS YP_001731310.1 170081990 6059955 complement(2583554..2584189) 1 NC_010473.1 hypothetical protein 2584189 yfdX 6059955 yfdX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731310.1 2583554 R 316385 CDS YP_001731311.1 170081991 6059957 2584485..2584760 1 NC_010473.1 lipoprotein involved in colanic acid biosynthesis 2584760 ypdI 6059957 ypdI Escherichia coli str. K-12 substr. DH10B lipoprotein involved in colanic acid biosynthesis YP_001731311.1 2584485 D 316385 CDS YP_001731312.1 170081992 6059958 complement(2584837..2585079) 1 NC_010473.1 inner membrane protein 2585079 yfdY 6059958 yfdY Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731312.1 2584837 R 316385 CDS YP_001731313.1 170081993 6059959 2585432..2586352 1 NC_010473.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2586352 lpxP 6059959 lpxP Escherichia coli str. K-12 substr. DH10B lipid A biosynthesis palmitoleoyl acyltransferase YP_001731313.1 2585432 D 316385 CDS YP_001731314.1 170081994 6059960 complement(2586844..2588082) 1 NC_010473.1 aminotransferase 2588082 yfdZ 6059960 yfdZ Escherichia coli str. K-12 substr. DH10B aminotransferase YP_001731314.1 2586844 R 316385 CDS YP_001731315.1 170081995 6059961 2588458..2590155 1 NC_010473.1 sensory kinase in two-component system with YpdB 2590155 ypdA 6059961 ypdA Escherichia coli str. K-12 substr. DH10B sensory kinase in two-component system with YpdB YP_001731315.1 2588458 D 316385 CDS YP_001731316.1 170081996 6059962 2590170..2590904 1 NC_010473.1 response regulator in two-component system withYpdA 2590904 ypdB 6059962 ypdB Escherichia coli str. K-12 substr. DH10B response regulator in two-component system withYpdA YP_001731316.1 2590170 D 316385 CDS YP_001731317.1 170081997 6059963 2590917..2591774 1 NC_010473.1 DNA-binding protein 2591774 ypdC 6059963 ypdC Escherichia coli str. K-12 substr. DH10B DNA-binding protein YP_001731317.1 2590917 D 316385 CDS YP_001731318.1 170081998 6059967 complement(2591777..2594272) 1 NC_010473.1 fused PTS enzymes: Hpr component; enzyme I component; enzyme IIA component 2594272 ypdD 6059967 ypdD Escherichia coli str. K-12 substr. DH10B fused PTS enzymes: Hpr component; enzyme I component; enzyme IIA component YP_001731318.1 2591777 R 316385 CDS YP_001731319.1 170081999 6059969 complement(2594297..2595334) 1 NC_010473.1 metalloprotein; exoaminopeptidase 2595334 ypdE 6059969 ypdE Escherichia coli str. K-12 substr. DH10B exoaminopeptidase YP_001731319.1 2594297 R 316385 CDS YP_001731320.1 170082000 6059970 complement(2595334..2596419) 1 NC_010473.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2596419 ypdF 6059970 ypdF Escherichia coli str. K-12 substr. DH10B aminopeptidase YP_001731320.1 2595334 R 316385 CDS YP_001731321.1 170082001 6059971 complement(2596434..2597681) 1 NC_010473.1 enzyme IIC component of PTS 2597681 ypdG 6059971 ypdG Escherichia coli str. K-12 substr. DH10B enzyme IIC component of PTS YP_001731321.1 2596434 R 316385 CDS YP_001731322.1 170082002 6059975 complement(2597703..2598029) 1 NC_010473.1 enzyme IIB component of PTS 2598029 ypdH 6059975 ypdH Escherichia coli str. K-12 substr. DH10B enzyme IIB component of PTS YP_001731322.1 2597703 R 316385 CDS YP_001731323.1 170082003 6059977 complement(2598248..2599213) 1 NC_010473.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2599213 glk 6059977 glk Escherichia coli str. K-12 substr. DH10B glucokinase YP_001731323.1 2598248 R 316385 CDS YP_001731324.1 170082004 6059978 2599417..2600673 1 NC_010473.1 hypothetical protein 2600673 yfeO 6059978 yfeO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731324.1 2599417 D 316385 CDS YP_001731325.1 170082005 6059979 2600788..2601114 1 NC_010473.1 hypothetical protein 2601114 ypeC 6059979 ypeC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731325.1 2600788 D 316385 CDS YP_001731326.1 170082006 6059981 complement(2601255..2602493) 1 NC_010473.1 manganese transport protein MntH 2602493 mntH 6059981 mntH Escherichia coli str. K-12 substr. DH10B manganese transport protein MntH YP_001731326.1 2601255 R 316385 CDS YP_001731327.1 170082007 6059982 2602829..2604031 1 NC_010473.1 nucleoside (except guanosine) transporter 2604031 nupC 6059982 nupC Escherichia coli str. K-12 substr. DH10B nucleoside (except guanosine) transporter YP_001731327.1 2602829 D 316385 CDS YP_001731328.1 170082008 6059984 2604118..2605230 1 NC_010473.1 IS186/IS421 transposase 2605230 insL-3 6059984 insL-3 Escherichia coli str. K-12 substr. DH10B IS186/IS421 transposase YP_001731328.1 2604118 D 316385 CDS YP_001731329.1 170082009 6059989 complement(2605430..2607619) 1 NC_010473.1 diguanylate cyclase 2607619 yfeA 6059989 yfeA Escherichia coli str. K-12 substr. DH10B diguanylate cyclase YP_001731329.1 2605430 R 316385 CDS YP_001731330.1 170082010 6059986 2608254..2608598 1 NC_010473.1 DNA-binding transcriptional regulator 2608598 yfeC 6059986 yfeC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731330.1 2608254 D 316385 CDS YP_001731331.1 170082011 6059991 2608600..2608992 1 NC_010473.1 DNA-binding transcriptional regulator 2608992 yfeD 6059991 yfeD Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731331.1 2608600 D 316385 CDS YP_001731332.1 170082012 6059993 complement(2609044..2610459) 1 NC_010473.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2610459 gltX 6059993 gltX Escherichia coli str. K-12 substr. DH10B glutamyl-tRNA synthetase YP_001731332.1 2609044 R 316385 CDS YP_001731333.1 170082013 6059514 complement(2611380..2612264) 1 NC_010473.1 DNA-binding transcriptional activator XapR 2612264 xapR 6059514 xapR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator XapR YP_001731333.1 2611380 R 316385 CDS YP_001731334.1 170082014 6059996 complement(2612516..2613772) 1 NC_010473.1 xanthosine transporter 2613772 xapB 6059996 xapB Escherichia coli str. K-12 substr. DH10B xanthosine transporter YP_001731334.1 2612516 R 316385 CDS YP_001731335.1 170082015 6059999 complement(2613832..2614665) 1 NC_010473.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 2614665 xapA 6059999 xapA Escherichia coli str. K-12 substr. DH10B purine nucleoside phosphorylase YP_001731335.1 2613832 R 316385 CDS YP_001731336.1 170082016 6060002 2614914..2615678 1 NC_010473.1 hypothetical protein 2615678 yfeN 6060002 yfeN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731336.1 2614914 D 316385 CDS YP_001731337.1 170082017 6060004 complement(2615717..2616643) 1 NC_010473.1 DNA-binding transcriptional regulator 2616643 yfeR 6060004 yfeR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731337.1 2615717 R 316385 CDS YP_001731338.1 170082018 6060005 2616733..2617731 1 NC_010473.1 inner membrane protein 2617731 yfeH 6060005 yfeH Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731338.1 2616733 D 316385 CDS YP_001731339.1 170082019 6060006 complement(2617728..2617946) 1 NC_010473.1 hypothetical protein 2617946 ypeB 6060006 ypeB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731339.1 2617728 R 316385 CDS YP_001731340.1 170082020 6060009 complement(2617948..2619963) 1 NC_010473.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2619963 ligA 6060009 ligA Escherichia coli str. K-12 substr. DH10B NAD-dependent DNA ligase LigA YP_001731340.1 2617948 R 316385 CDS YP_001731341.1 170082021 6060013 complement(2620034..2621020) 1 NC_010473.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2621020 zipA 6060013 zipA Escherichia coli str. K-12 substr. DH10B cell division protein ZipA YP_001731341.1 2620034 R 316385 CDS YP_001731342.1 170082022 6060018 2621250..2622011 1 NC_010473.1 putative role in sulfur assimilation; putative sulfate transport protein CysZ 2622011 cysZ 6060018 cysZ Escherichia coli str. K-12 substr. DH10B putative sulfate transport protein CysZ YP_001731342.1 2621250 D 316385 CDS YP_001731343.1 170082023 6060020 2622196..2623167 1 NC_010473.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2623167 cysK 6060020 cysK Escherichia coli str. K-12 substr. DH10B cysteine synthase A YP_001731343.1 2622196 D 316385 CDS YP_001731344.1 170082024 6060021 2623551..2623808 1 NC_010473.1 PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 2623808 ptsH 6060021 ptsH Escherichia coli str. K-12 substr. DH10B PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr YP_001731344.1 2623551 D 316385 CDS YP_001731345.1 170082025 6060023 2623853..2625580 1 NC_010473.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2625580 ptsI 6060023 ptsI Escherichia coli str. K-12 substr. DH10B phosphoenolpyruvate-protein phosphotransferase YP_001731345.1 2623853 D 316385 CDS YP_001731346.1 170082026 6060024 2625621..2626130 1 NC_010473.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2626130 crr 6060024 crr Escherichia coli str. K-12 substr. DH10B PTS system glucose-specific transporter YP_001731346.1 2625621 D 316385 CDS YP_001731347.1 170082027 6060028 complement(2626173..2627024) 1 NC_010473.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2627024 pdxK 6060028 pdxK Escherichia coli str. K-12 substr. DH10B pyridoxal kinase YP_001731347.1 2626173 R 316385 CDS YP_001731348.1 170082028 6060033 2627129..2627503 1 NC_010473.1 hypothetical protein 2627503 yfeK 6060033 yfeK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731348.1 2627129 D 316385 CDS YP_001731349.1 170082029 6060034 2627536..2628270 1 NC_010473.1 hypothetical protein 2628270 yfeS 6060034 yfeS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731349.1 2627536 D 316385 CDS YP_001731350.1 170082030 6060035 complement(2628459..2629370) 1 NC_010473.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2629370 cysM 6060035 cysM Escherichia coli str. K-12 substr. DH10B cysteine synthase B YP_001731350.1 2628459 R 316385 CDS YP_001731351.1 170082031 6060036 complement(2629504..2630601) 1 NC_010473.1 sulfate/thiosulfate transporter subunit 2630601 cysA 6060036 cysA Escherichia coli str. K-12 substr. DH10B sulfate/thiosulfate transporter subunit YP_001731351.1 2629504 R 316385 CDS YP_001731352.1 170082032 6060038 complement(2630591..2631466) 1 NC_010473.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 2631466 cysW 6060038 cysW Escherichia coli str. K-12 substr. DH10B sulfate/thiosulfate transporter permease subunit YP_001731352.1 2630591 R 316385 CDS YP_001731353.1 170082033 6060041 complement(2631466..2632299) 1 NC_010473.1 sulfate/thiosulfate transporter subunit 2632299 cysU 6060041 cysU Escherichia coli str. K-12 substr. DH10B sulfate/thiosulfate transporter subunit YP_001731353.1 2631466 R 316385 CDS YP_001731354.1 170082034 6060042 complement(2632299..2633315) 1 NC_010473.1 thiosulfate transporter subunit 2633315 cysP 6060042 cysP Escherichia coli str. K-12 substr. DH10B thiosulfate transporter subunit YP_001731354.1 2632299 R 316385 CDS YP_001731355.1 170082035 6060043 complement(2633619..2634410) 1 NC_010473.1 short chain dehydrogenase 2634410 ucpA 6060043 ucpA Escherichia coli str. K-12 substr. DH10B short chain dehydrogenase YP_001731355.1 2633619 R 316385 CDS YP_001731356.1 170082036 6060045 complement(2634539..2635396) 1 NC_010473.1 DNA-binding transcriptional regulator 2635396 yfeT 6060045 yfeT Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731356.1 2634539 R 316385 CDS YP_001731357.1 170082037 6060046 2635560..2636456 1 NC_010473.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2636456 murQ 6060046 murQ Escherichia coli str. K-12 substr. DH10B N-acetylmuramic acid 6-phosphate etherase YP_001731357.1 2635560 D 316385 CDS YP_001731358.1 170082038 6060047 2636460..2637884 1 NC_010473.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2637884 murP 6060047 murP Escherichia coli str. K-12 substr. DH10B PTS system N-acetylmuramic acid transporter subunit IIBC YP_001731358.1 2636460 D 316385 CDS YP_001731359.1 170082039 6060048 2637889..2639193 1 NC_010473.1 hypothetical protein 2639193 yfeW 6060048 yfeW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731359.1 2637889 D 316385 CDS YP_001731360.1 170082040 6060050 complement(2639433..2640332) 1 NC_010473.1 hypothetical protein 2640332 yfeX 6060050 yfeX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731360.1 2639433 R 316385 CDS YP_001731361.1 170082041 6060051 complement(2640428..2641003) 1 NC_010473.1 hypothetical protein 2641003 yfeY 6060051 yfeY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731361.1 2640428 R 316385 CDS YP_001731362.1 170082042 6060052 complement(2641064..2641513) 1 NC_010473.1 inner membrane protein 2641513 yfeZ 6060052 yfeZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731362.1 2641064 R 316385 CDS YP_001731363.1 170082043 6060055 complement(2641500..2641925) 1 NC_010473.1 putative acetyltransferase 2641925 ypeA 6060055 ypeA Escherichia coli str. K-12 substr. DH10B putative acetyltransferase YP_001731363.1 2641500 R 316385 CDS YP_001731364.1 170082044 6060057 2642139..2643008 1 NC_010473.1 N-acetylmuramoyl-l-alanine amidase I 2643008 amiA 6060057 amiA Escherichia coli str. K-12 substr. DH10B N-acetylmuramoyl-l-alanine amidase I YP_001731364.1 2642139 D 316385 CDS YP_001731365.1 170082045 6060058 2643012..2643911 1 NC_010473.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2643911 hemF 6060058 hemF Escherichia coli str. K-12 substr. DH10B coproporphyrinogen III oxidase YP_001731365.1 2643012 D 316385 CDS YP_001731366.1 170082046 6060061 complement(2643917..2644969) 1 NC_010473.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2644969 yfeG 6060061 yfeG Escherichia coli str. K-12 substr. DH10B transcriptional regulator EutR YP_001731366.1 2643917 R 316385 CDS YP_001731367.1 170082047 6060063 complement(2645015..2645515) 1 NC_010473.1 ethanolamine utilization carboxysome structural protein 2645515 yffI 6060063 yffI Escherichia coli str. K-12 substr. DH10B ethanolamine utilization carboxysome structural protein YP_001731367.1 2645015 R 316385 CDS YP_001731368.1 170082048 6060064 complement(2645528..2646187) 1 NC_010473.1 ethanolamine utilization carboxysome structural protein 2646187 eutL 6060064 eutL Escherichia coli str. K-12 substr. DH10B ethanolamine utilization carboxysome structural protein YP_001731368.1 2645528 R 316385 CDS YP_001731369.1 170082049 6060065 complement(2646197..2647084) 1 NC_010473.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2647084 eutC 6060065 eutC Escherichia coli str. K-12 substr. DH10B ethanolamine ammonia-lyase small subunit YP_001731369.1 2646197 R 316385 CDS YP_001731370.1 170082050 6060066 complement(2647105..2648466) 1 NC_010473.1 ethanolamine ammonia-lyase, large subunit, heavy chain 2648466 eutB 6060066 eutB Escherichia coli str. K-12 substr. DH10B ethanolamine ammonia-lyase, large subunit, heavy chain YP_001731370.1 2647105 R 316385 CDS YP_001731371.1 170082051 6060069 2648558..2649853 1 NC_010473.1 CPZ-55 prophage; integrase 2649853 intZ 6060069 intZ Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; integrase YP_001731371.1 2648558 D 316385 CDS YP_001731372.1 170082052 6060070 2650044..2650685 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2650685 yffL 6060070 yffL Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731372.1 2650044 D 316385 CDS YP_001731373.1 170082053 6060072 2651155..2651400 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2651400 yffM 6060072 yffM Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731373.1 2651155 D 316385 CDS YP_001731374.1 170082054 6060075 2651397..2651780 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2651780 yffN 6060075 yffN Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731374.1 2651397 D 316385 CDS YP_001731375.1 170082055 6060078 2651898..2652314 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2652314 yffO 6060078 yffO Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731375.1 2651898 D 316385 CDS YP_001731376.1 170082056 6060079 2652311..2652904 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2652904 yffP 6060079 yffP Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731376.1 2652311 D 316385 CDS YP_001731377.1 170082057 6060098 2653364..2653756 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2653756 yffQ 6060098 yffQ Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731377.1 2653364 D 316385 CDS YP_001731378.1 170082058 6060099 2653767..2654159 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2654159 yffR 6060099 yffR Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731378.1 2653767 D 316385 CDS YP_001731379.1 170082059 6060102 2654280..2655119 1 NC_010473.1 CPZ-55 prophage; hypothetical protein 2655119 yffS 6060102 yffS Escherichia coli str. K-12 substr. DH10B CPZ-55 prophage; hypothetical protein YP_001731379.1 2654280 D 316385 CDS YP_001731380.1 170082060 6060106 complement(2655268..2656671) 1 NC_010473.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2656671 eutA 6060106 eutA Escherichia coli str. K-12 substr. DH10B reactivating factor for ethanolamine ammonia lyase YP_001731380.1 2655268 R 316385 CDS YP_001731381.1 170082061 6060107 complement(2656668..2657894) 1 NC_010473.1 inner membrane protein 2657894 eutH 6060107 eutH Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731381.1 2656668 R 316385 CDS YP_001731382.1 170082062 6060108 complement(2658111..2659298) 1 NC_010473.1 alcohol dehydrogenase in ethanolamine utilization 2659298 eutG 6060108 eutG Escherichia coli str. K-12 substr. DH10B alcohol dehydrogenase in ethanolamine utilization YP_001731382.1 2658111 R 316385 CDS YP_001731383.1 170082063 6060109 complement(2659288..2660124) 1 NC_010473.1 chaperonin, ethanolamine utilization protein 2660124 eutJ 6060109 eutJ Escherichia coli str. K-12 substr. DH10B chaperonin, ethanolamine utilization protein YP_001731383.1 2659288 R 316385 CDS YP_001731384.1 170082064 6060112 complement(2660135..2661538) 1 NC_010473.1 aldehyde dehydrogenase 2661538 eutE 6060112 eutE Escherichia coli str. K-12 substr. DH10B aldehyde dehydrogenase YP_001731384.1 2660135 R 316385 CDS YP_001731385.1 170082065 6060114 complement(2661550..2661837) 1 NC_010473.1 ethanolamine utilization carboxysome structural protein 2661837 cchB 6060114 cchB Escherichia coli str. K-12 substr. DH10B ethanolamine utilization carboxysome structural protein YP_001731385.1 2661550 R 316385 CDS YP_001731386.1 170082066 6060118 complement(2661944..2662237) 1 NC_010473.1 ethanolamine utilization carboxysome structural protein 2662237 cchA 6060118 cchA Escherichia coli str. K-12 substr. DH10B ethanolamine utilization carboxysome structural protein YP_001731386.1 2661944 R 316385 CDS YP_001731387.1 170082067 6060119 complement(2662276..2663292) 1 NC_010473.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2663292 eutD 6060119 eutD Escherichia coli str. K-12 substr. DH10B phosphotransacetylase YP_001731387.1 2662276 R 316385 CDS YP_001731388.1 170082068 6060127 complement(2663289..2664092) 1 NC_010473.1 cobalamin adenosyltransferase in ethanolamine utilization 2664092 eutT 6060127 eutT Escherichia coli str. K-12 substr. DH10B cobalamin adenosyltransferase in ethanolamine utilization YP_001731388.1 2663289 R 316385 CDS YP_001731389.1 170082069 6060129 complement(2664089..2664790) 1 NC_010473.1 hypothetical protein 2664790 eutQ 6060129 eutQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731389.1 2664089 R 316385 CDS YP_001731390.1 170082070 6060130 complement(2664765..2665244) 1 NC_010473.1 hypothetical protein 2665244 eutP 6060130 eutP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731390.1 2664765 R 316385 CDS YP_001731391.1 170082071 6060132 complement(2665257..2665592) 1 NC_010473.1 ethanol utilization carboxysome structural protein 2665592 ypfE 6060132 ypfE Escherichia coli str. K-12 substr. DH10B ethanol utilization carboxysome structural protein YP_001731391.1 2665257 R 316385 CDS YP_001731392.1 170082072 6060134 complement(2665885..2668164) 1 NC_010473.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2668164 maeB 6060134 maeB Escherichia coli str. K-12 substr. DH10B malic enzyme YP_001731392.1 2665885 R 316385 CDS YP_001731393.1 170082073 6060135 2668453..2669403 1 NC_010473.1 transaldolase A 2669403 talA 6060135 talA Escherichia coli str. K-12 substr. DH10B transaldolase A YP_001731393.1 2668453 D 316385 CDS YP_001731394.1 170082074 6060140 2669423..2671426 1 NC_010473.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2671426 tktB 6060140 tktB Escherichia coli str. K-12 substr. DH10B transketolase YP_001731394.1 2669423 D 316385 CDS YP_001731395.1 170082075 6060142 complement(2671521..2672564) 1 NC_010473.1 hypothetical protein 2672564 ypfG 6060142 ypfG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731395.1 2671521 R 316385 CDS YP_001731396.1 170082076 6060143 complement(2672690..2673265) 1 NC_010473.1 NUDIX hydrolase 2673265 yffH 6060143 yffH Escherichia coli str. K-12 substr. DH10B NUDIX hydrolase YP_001731396.1 2672690 R 316385 CDS YP_001731397.1 170082077 6060146 complement(2673333..2675312) 1 NC_010473.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 2675312 aegA 6060146 aegA Escherichia coli str. K-12 substr. DH10B putative oxidoreductase Fe-S binding subunit YP_001731397.1 2673333 R 316385 CDS YP_001731398.1 170082078 6060147 2675518..2677218 1 NC_010473.1 nitrate/nitrite sensor protein NarQ 2677218 narQ 6060147 narQ Escherichia coli str. K-12 substr. DH10B nitrate/nitrite sensor protein NarQ YP_001731398.1 2675518 D 316385 CDS YP_001731399.1 170082079 6060148 2677382..2680495 1 NC_010473.1 aminoglycoside/multidrug efflux system 2680495 acrD 6060148 acrD Escherichia coli str. K-12 substr. DH10B aminoglycoside/multidrug efflux system YP_001731399.1 2677382 D 316385 CDS YP_001731400.1 170082080 6060150 2681034..2681390 1 NC_010473.1 hypothetical protein 2681390 yffB 6060150 yffB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731400.1 2681034 D 316385 CDS YP_001731401.1 170082081 6060158 2681394..2682521 1 NC_010473.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2682521 dapE 6060158 dapE Escherichia coli str. K-12 substr. DH10B succinyl-diaminopimelate desuccinylase YP_001731401.1 2681394 D 316385 CDS YP_001731402.1 170082082 6060160 2682549..2682749 1 NC_010473.1 hypothetical protein 2682749 ypfN 6060160 ypfN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731402.1 2682549 D 316385 CDS YP_001731403.1 170082083 6060163 complement(2682859..2683557) 1 NC_010473.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 2683557 ypfH 6060163 ypfH Escherichia coli str. K-12 substr. DH10B esterase YpfH YP_001731403.1 2682859 R 316385 CDS YP_001731404.1 170082084 6060168 complement(2683631..2685646) 1 NC_010473.1 hydrolase 2685646 ypfI 6060168 ypfI Escherichia coli str. K-12 substr. DH10B hydrolase YP_001731404.1 2683631 R 316385 CDS YP_001731405.1 170082085 6060172 complement(2685661..2686524) 1 NC_010473.1 hypothetical protein 2686524 ypfJ 6060172 ypfJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731405.1 2685661 R 316385 CDS YP_001731406.1 170082086 6060174 complement(2686692..2687405) 1 NC_010473.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2687405 purC 6060174 purC Escherichia coli str. K-12 substr. DH10B phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001731406.1 2686692 R 316385 CDS YP_001731407.1 170082087 6060179 complement(2687618..2688652) 1 NC_010473.1 lipoprotein 2688652 nlpB 6060179 nlpB Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001731407.1 2687618 R 316385 CDS YP_001731408.1 170082088 6060180 complement(2688669..2689547) 1 NC_010473.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2689547 dapA 6060180 dapA Escherichia coli str. K-12 substr. DH10B dihydrodipicolinate synthase YP_001731408.1 2688669 R 316385 CDS YP_001731409.1 170082089 6060184 2689693..2690265 1 NC_010473.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2690265 gcvR 6060184 gcvR Escherichia coli str. K-12 substr. DH10B glycine cleavage system transcriptional repressor YP_001731409.1 2689693 D 316385 CDS YP_001731410.1 170082090 6060187 2690265..2690735 1 NC_010473.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2690735 bcp 6060187 bcp Escherichia coli str. K-12 substr. DH10B thioredoxin-dependent thiol peroxidase YP_001731410.1 2690265 D 316385 CDS YP_001731411.1 170082091 6060192 2690988..2691605 1 NC_010473.1 hydrogenase 4, 4Fe-4S subunit 2691605 hyfA 6060192 hyfA Escherichia coli str. K-12 substr. DH10B hydrogenase 4, 4Fe-4S subunit YP_001731411.1 2690988 D 316385 CDS YP_001731412.1 170082092 6060195 2691605..2693623 1 NC_010473.1 hydrogenase 4 subunit B 2693623 hyfB 6060195 hyfB Escherichia coli str. K-12 substr. DH10B hydrogenase 4 subunit B YP_001731412.1 2691605 D 316385 CDS YP_001731413.1 170082093 6060209 2693634..2694581 1 NC_010473.1 hydrogenase 4, membrane subunit 2694581 hyfC 6060209 hyfC Escherichia coli str. K-12 substr. DH10B hydrogenase 4, membrane subunit YP_001731413.1 2693634 D 316385 CDS YP_001731414.1 170082094 6060212 2694598..2696037 1 NC_010473.1 hydrogenase 4 subunit D 2696037 hyfD 6060212 hyfD Escherichia coli str. K-12 substr. DH10B hydrogenase 4 subunit D YP_001731414.1 2694598 D 316385 CDS YP_001731415.1 170082095 6060213 2696049..2696699 1 NC_010473.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2696699 hyfE 6060213 hyfE Escherichia coli str. K-12 substr. DH10B hydrogenase 4 membrane subunit YP_001731415.1 2696049 D 316385 CDS YP_001731416.1 170082096 6060216 2696704..2698284 1 NC_010473.1 hydrogenase 4 subunit F 2698284 hyfF 6060216 hyfF Escherichia coli str. K-12 substr. DH10B hydrogenase 4 subunit F YP_001731416.1 2696704 D 316385 CDS YP_001731417.1 170082097 6060217 2698274..2699941 1 NC_010473.1 hydrogenase 4 subunit 2699941 hyfG 6060217 hyfG Escherichia coli str. K-12 substr. DH10B hydrogenase 4 subunit YP_001731417.1 2698274 D 316385 CDS YP_001731418.1 170082098 6060219 2699951..2700496 1 NC_010473.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2700496 hyfH 6060219 hyfH Escherichia coli str. K-12 substr. DH10B hydrogenase 4 subunit H YP_001731418.1 2699951 D 316385 CDS YP_001731419.1 170082099 6060222 2700493..2701251 1 NC_010473.1 hydrogenase 4, Fe-S subunit 2701251 hyfI 6060222 hyfI Escherichia coli str. K-12 substr. DH10B hydrogenase 4, Fe-S subunit YP_001731419.1 2700493 D 316385 CDS YP_001731420.1 170082100 6060227 2701244..2701657 1 NC_010473.1 processing element hydrogenase 4 2701657 hyfJ 6060227 hyfJ Escherichia coli str. K-12 substr. DH10B processing element hydrogenase 4 YP_001731420.1 2701244 D 316385 CDS YP_001731421.1 170082101 6060233 2701687..2703699 1 NC_010473.1 DNA-binding transcriptional activator, formate sensing 2703699 hyfR 6060233 hyfR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator, formate sensing YP_001731421.1 2701687 D 316385 CDS YP_001731422.1 170082102 6060234 2703721..2704569 1 NC_010473.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter 2704569 focB 6060234 focB Escherichia coli str. K-12 substr. DH10B putative formate transporter YP_001731422.1 2703721 D 316385 CDS YP_001731423.1 170082103 6060243 complement(2704607..2705668) 1 NC_010473.1 inner membrane protein 2705668 yfgO 6060243 yfgO Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731423.1 2704607 R 316385 CDS YP_001731424.1 170082104 6060246 2705881..2707344 1 NC_010473.1 peptidase 2707344 yfgC 6060246 yfgC Escherichia coli str. K-12 substr. DH10B peptidase YP_001731424.1 2705881 D 316385 CDS YP_001731425.1 170082105 6060255 2707365..2707724 1 NC_010473.1 oxidoreductase 2707724 yfgD 6060255 yfgD Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001731425.1 2707365 D 316385 CDS YP_001731426.1 170082106 6060260 complement(2707862..2708608) 1 NC_010473.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2708608 hda 6060260 hda Escherichia coli str. K-12 substr. DH10B DNA replication initiation factor YP_001731426.1 2707862 R 316385 CDS YP_001731427.1 170082107 6060191 complement(2708658..2709947) 1 NC_010473.1 uracil transporter 2709947 uraA 6060191 uraA Escherichia coli str. K-12 substr. DH10B uracil transporter YP_001731427.1 2708658 R 316385 CDS YP_001731428.1 170082108 6060267 complement(2710033..2710659) 1 NC_010473.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2710659 upp 6060267 upp Escherichia coli str. K-12 substr. DH10B uracil phosphoribosyltransferase YP_001731428.1 2710033 R 316385 CDS YP_001731429.1 170082109 6060270 2710984..2712021 1 NC_010473.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2712021 purM 6060270 purM Escherichia coli str. K-12 substr. DH10B phosphoribosylaminoimidazole synthetase YP_001731429.1 2710984 D 316385 CDS YP_001731430.1 170082110 6060274 2712021..2712659 1 NC_010473.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2712659 purN 6060274 purN Escherichia coli str. K-12 substr. DH10B phosphoribosylglycinamide formyltransferase YP_001731430.1 2712021 D 316385 CDS YP_001731431.1 170082111 6060278 2712831..2714897 1 NC_010473.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2714897 ppk 6060278 ppk Escherichia coli str. K-12 substr. DH10B polyphosphate kinase YP_001731431.1 2712831 D 316385 CDS YP_001731432.1 170082112 6060279 2714902..2716443 1 NC_010473.1 exopolyphosphatase 2716443 ppx 6060279 ppx Escherichia coli str. K-12 substr. DH10B exopolyphosphatase YP_001731432.1 2714902 D 316385 CDS YP_001731433.1 170082113 6060280 complement(2716482..2718725) 1 NC_010473.1 inner membrane protein 2718725 yfgF 6060280 yfgF Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731433.1 2716482 R 316385 CDS YP_001731434.1 170082114 6060281 2719077..2719268 1 NC_010473.1 hypothetical protein 2719268 yfgG 6060281 yfgG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731434.1 2719077 D 316385 CDS YP_001731435.1 170082115 6060284 2719579..2720097 1 NC_010473.1 outer membrane lipoprotein 2720097 yfgH 6060284 yfgH Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein YP_001731435.1 2719579 D 316385 CDS YP_001731436.1 170082116 6060285 2720113..2720652 1 NC_010473.1 hypothetical protein 2720652 yfgI 6060285 yfgI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731436.1 2720113 D 316385 CDS YP_001731437.1 170082117 6060288 complement(2720745..2722322) 1 NC_010473.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2722322 guaA 6060288 guaA Escherichia coli str. K-12 substr. DH10B GMP synthase YP_001731437.1 2720745 R 316385 CDS YP_001731438.1 170082118 6060291 complement(2722391..2723857) 1 NC_010473.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2723857 guaB 6060291 guaB Escherichia coli str. K-12 substr. DH10B inosine 5'-monophosphate dehydrogenase YP_001731438.1 2722391 R 316385 CDS YP_001731439.1 170082119 6060294 2724019..2725389 1 NC_010473.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2725389 xseA 6060294 xseA Escherichia coli str. K-12 substr. DH10B exodeoxyribonuclease VII large subunit YP_001731439.1 2724019 D 316385 CDS YP_001731440.1 170082120 6060295 complement(2725386..2725601) 1 NC_010473.1 hypothetical protein 2725601 yfgJ 6060295 yfgJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731440.1 2725386 R 316385 CDS YP_001731441.1 170082121 6060298 complement(2725671..2727143) 1 NC_010473.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2727143 engA 6060298 engA Escherichia coli str. K-12 substr. DH10B GTP-binding protein EngA YP_001731441.1 2725671 R 316385 CDS YP_001731442.1 170082122 6060301 complement(2727261..2728439) 1 NC_010473.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2728439 yfgL 6060301 yfgL Escherichia coli str. K-12 substr. DH10B outer membrane protein assembly complex subunit YfgL YP_001731442.1 2727261 R 316385 CDS YP_001731443.1 170082123 6060310 complement(2728450..2729070) 1 NC_010473.1 hypothetical protein 2729070 yfgM 6060310 yfgM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731443.1 2728450 R 316385 CDS YP_001731444.1 170082124 6060322 complement(2729088..2730362) 1 NC_010473.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2730362 hisS 6060322 hisS Escherichia coli str. K-12 substr. DH10B histidyl-tRNA synthetase YP_001731444.1 2729088 R 316385 CDS YP_001731445.1 170082125 6060323 complement(2730473..2731591) 1 NC_010473.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2731591 ispG 6060323 ispG Escherichia coli str. K-12 substr. DH10B 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001731445.1 2730473 R 316385 CDS YP_001731446.1 170082126 6060342 complement(2731618..2732631) 1 NC_010473.1 cytoskeletal protein RodZ 2732631 yfgA 6060342 yfgA Escherichia coli str. K-12 substr. DH10B cytoskeletal protein RodZ YP_001731446.1 2731618 R 316385 CDS YP_001731447.1 170082127 6060344 complement(2732916..2734070) 1 NC_010473.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2734070 yfgB 6060344 yfgB Escherichia coli str. K-12 substr. DH10B ribosomal RNA large subunit methyltransferase N YP_001731447.1 2732916 R 316385 CDS YP_001731448.1 170082128 6060348 complement(2734220..2734651) 1 NC_010473.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2734651 ndk 6060348 ndk Escherichia coli str. K-12 substr. DH10B nucleoside diphosphate kinase YP_001731448.1 2734220 R 316385 CDS YP_001731449.1 170082129 6060350 complement(2734800..2737112) 1 NC_010473.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2737112 pbpC 6060350 pbpC Escherichia coli str. K-12 substr. DH10B penicillin-binding protein 1C YP_001731449.1 2734800 R 316385 CDS YP_001731450.1 170082130 6060351 complement(2737113..2742074) 1 NC_010473.1 hypothetical protein 2742074 yfhM 6060351 yfhM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731450.1 2737113 R 316385 CDS YP_001731451.1 170082131 6060352 2742281..2743126 1 NC_010473.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2743126 sseA 6060352 sseA Escherichia coli str. K-12 substr. DH10B 3-mercaptopyruvate sulfurtransferase YP_001731451.1 2742281 D 316385 CDS YP_001731452.1 170082132 6058783 complement(2743944..2744720) 1 NC_010473.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2744720 sseB 6058783 sseB Escherichia coli str. K-12 substr. DH10B enhanced serine sensitivity protein SseB YP_001731452.1 2743944 R 316385 CDS YP_001731453.1 170082133 6060361 complement(2744862..2746145) 1 NC_010473.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 2746145 pepB 6060361 pepB Escherichia coli str. K-12 substr. DH10B aminopeptidase B YP_001731453.1 2744862 R 316385 CDS YP_001731454.1 170082134 6060366 complement(2746323..2746523) 1 NC_010473.1 hypothetical protein 2746523 yfhJ 6060366 yfhJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731454.1 2746323 R 316385 CDS YP_001731455.1 170082135 6060367 complement(2746535..2746870) 1 NC_010473.1 [2Fe-2S] ferredoxin 2746870 fdx 6060367 fdx Escherichia coli str. K-12 substr. DH10B [2Fe-2S] ferredoxin YP_001731455.1 2746535 R 316385 CDS YP_001731456.1 170082136 6060385 complement(2746872..2748722) 1 NC_010473.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2748722 hscA 6060385 hscA Escherichia coli str. K-12 substr. DH10B chaperone protein HscA YP_001731456.1 2746872 R 316385 CDS YP_001731457.1 170082137 6060391 complement(2748739..2749254) 1 NC_010473.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2749254 hscB 6060391 hscB Escherichia coli str. K-12 substr. DH10B co-chaperone HscB YP_001731457.1 2748739 R 316385 CDS YP_001731458.1 170082138 6060393 complement(2749350..2749673) 1 NC_010473.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2749673 iscA 6060393 iscA Escherichia coli str. K-12 substr. DH10B iron-sulfur cluster assembly protein YP_001731458.1 2749350 R 316385 CDS YP_001731459.1 170082139 6060399 complement(2749690..2750076) 1 NC_010473.1 scaffold protein 2750076 iscU 6060399 iscU Escherichia coli str. K-12 substr. DH10B scaffold protein YP_001731459.1 2749690 R 316385 CDS YP_001731460.1 170082140 6060401 complement(2750104..2751318) 1 NC_010473.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2751318 iscS 6060401 iscS Escherichia coli str. K-12 substr. DH10B cysteine desulfurase YP_001731460.1 2750104 R 316385 CDS YP_001731461.1 170082141 6060406 complement(2751430..2751918) 1 NC_010473.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2751918 iscR 6060406 iscR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator IscR YP_001731461.1 2751430 R 316385 CDS YP_001731462.1 170082142 6060416 complement(2752370..2753110) 1 NC_010473.1 methyltransferase 2753110 yfhQ 6060416 yfhQ Escherichia coli str. K-12 substr. DH10B methyltransferase YP_001731462.1 2752370 R 316385 CDS YP_001731463.1 170082143 6060418 2753229..2754032 1 NC_010473.1 inositol monophosphatase 2754032 suhB 6060418 suhB Escherichia coli str. K-12 substr. DH10B inositol monophosphatase YP_001731463.1 2753229 D 316385 CDS YP_001731464.1 170082144 6060442 2754150..2755031 1 NC_010473.1 peptidase 2755031 yfhR 6060442 yfhR Escherichia coli str. K-12 substr. DH10B peptidase YP_001731464.1 2754150 D 316385 CDS YP_001731465.1 170082145 6060443 2755222..2756502 1 NC_010473.1 stationary phase inducible protein CsiE 2756502 csiE 6060443 csiE Escherichia coli str. K-12 substr. DH10B stationary phase inducible protein CsiE YP_001731465.1 2755222 D 316385 CDS YP_001731466.1 170082146 6060444 complement(2756494..2757633) 1 NC_010473.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 2757633 hcaT 6060444 hcaT Escherichia coli str. K-12 substr. DH10B putative 3-phenylpropionic acid transporter YP_001731466.1 2756494 R 316385 CDS YP_001731467.1 170082147 6060445 complement(2757793..2758683) 1 NC_010473.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 2758683 hcaR 6060445 hcaR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator HcaR YP_001731467.1 2757793 R 316385 CDS YP_001731468.1 170082148 6062285 2758819..2760180 1 NC_010473.1 3-phenylpropionate dioxygenase, large (alpha) subunit 2760180 hcaE 6062285 hcaE Escherichia coli str. K-12 substr. DH10B 3-phenylpropionate dioxygenase, large (alpha) subunit YP_001731468.1 2758819 D 316385 CDS YP_001731469.1 170082149 6060450 2760177..2760695 1 NC_010473.1 3-phenylpropionate dioxygenase subunit beta 2760695 hcaF 6060450 hcaF Escherichia coli str. K-12 substr. DH10B 3-phenylpropionate dioxygenase subunit beta YP_001731469.1 2760177 D 316385 CDS YP_001731470.1 170082150 6060457 2760695..2761015 1 NC_010473.1 3-phenylpropionate dioxygenase ferredoxin subunit 2761015 hcaC 6060457 hcaC Escherichia coli str. K-12 substr. DH10B 3-phenylpropionate dioxygenase ferredoxin subunit YP_001731470.1 2760695 D 316385 CDS YP_001731471.1 170082151 6060465 2761012..2761824 1 NC_010473.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2761824 hcaB 6060465 hcaB Escherichia coli str. K-12 substr. DH10B 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_001731471.1 2761012 D 316385 CDS YP_001731472.1 170082152 6060470 2761834..2763036 1 NC_010473.1 phenylpropionate dioxygenase ferredoxin reductase subunit 2763036 hcaD 6060470 hcaD Escherichia coli str. K-12 substr. DH10B phenylpropionate dioxygenase ferredoxin reductase subunit YP_001731472.1 2761834 D 316385 CDS YP_001731473.1 170082153 6060474 2763061..2763555 1 NC_010473.1 inner membrane protein 2763555 yphA 6060474 yphA Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731473.1 2763061 D 316385 CDS YP_001731474.1 170082154 6060475 complement(2763603..2764475) 1 NC_010473.1 hypothetical protein 2764475 yphB 6060475 yphB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731474.1 2763603 R 316385 CDS YP_001731475.1 170082155 6060478 complement(2764487..2765548) 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 2765548 yphC 6060478 yphC Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001731475.1 2764487 R 316385 CDS YP_001731476.1 170082156 6060479 complement(2765614..2766612) 1 NC_010473.1 sugar ABC transporter membrane protein 2766612 yphD 6060479 yphD Escherichia coli str. K-12 substr. DH10B sugar ABC transporter membrane protein YP_001731476.1 2765614 R 316385 CDS YP_001731477.1 170082157 6060480 complement(2766637..2768148) 1 NC_010473.1 sugar ABC transporter ATP-binding protein 2768148 yphE 6060480 yphE Escherichia coli str. K-12 substr. DH10B sugar ABC transporter ATP-binding protein YP_001731477.1 2766637 R 316385 CDS YP_001731478.1 170082158 6060482 complement(2768171..2769154) 1 NC_010473.1 sugar ABC transporter periplasmic-binding protein 2769154 yphF 6060482 yphF Escherichia coli str. K-12 substr. DH10B sugar ABC transporter periplasmic-binding protein YP_001731478.1 2768171 R 316385 CDS YP_001731479.1 170082159 6060483 complement(2769251..2772532) 1 NC_010473.1 hypothetical protein 2772532 yphG 6060483 yphG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731479.1 2769251 R 316385 CDS YP_001731480.1 170082160 6060484 2772650..2773843 1 NC_010473.1 DNA-binding transcriptional regulator 2773843 yphH 6060484 yphH Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731480.1 2772650 D 316385 CDS YP_001731481.1 170082161 6060030 complement(2774041..2775294) 1 NC_010473.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2775294 glyA 6060030 glyA Escherichia coli str. K-12 substr. DH10B serine hydroxymethyltransferase YP_001731481.1 2774041 R 316385 CDS YP_001731482.1 170082162 6060485 2775622..2776812 1 NC_010473.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2776812 hmp 6060485 hmp Escherichia coli str. K-12 substr. DH10B nitric oxide dioxygenase YP_001731482.1 2775622 D 316385 CDS YP_001731483.1 170082163 6060490 complement(2776857..2777195) 1 NC_010473.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2777195 glnB 6060490 glnB Escherichia coli str. K-12 substr. DH10B nitrogen regulatory protein P-II 1 YP_001731483.1 2776857 R 316385 CDS YP_001731484.1 170082164 6060492 complement(2777256..2778590) 1 NC_010473.1 two component system DNA-binding response regulator 2778590 yfhA 6060492 yfhA Escherichia coli str. K-12 substr. DH10B two component system DNA-binding response regulator YP_001731484.1 2777256 R 316385 CDS YP_001731485.1 170082165 6060495 complement(2778580..2779293) 1 NC_010473.1 hypothetical protein 2779293 yfhG 6060495 yfhG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731485.1 2778580 R 316385 CDS YP_001731486.1 170082166 6060497 complement(2779458..2780885) 1 NC_010473.1 sensory kinase in two-component system 2780885 yfhK 6060497 yfhK Escherichia coli str. K-12 substr. DH10B sensory kinase in two-component system YP_001731486.1 2779458 R 316385 CDS YP_001731487.1 170082167 6060231 complement(2781443..2785330) 1 NC_010473.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2785330 purL 6060231 purL Escherichia coli str. K-12 substr. DH10B phosphoribosylformylglycinamidine synthase YP_001731487.1 2781443 R 316385 CDS YP_001731488.1 170082168 6060524 2785726..2787144 1 NC_010473.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 2787144 yfhD 6060524 yfhD Escherichia coli str. K-12 substr. DH10B putative transglycosylase YP_001731488.1 2785726 D 316385 CDS YP_001731489.1 170082169 6060542 complement(2787141..2787644) 1 NC_010473.1 tRNA-specific adenosine deaminase 2787644 tadA 6060542 tadA Escherichia coli str. K-12 substr. DH10B tRNA-specific adenosine deaminase YP_001731489.1 2787141 R 316385 CDS YP_001731490.1 170082170 6060552 complement(2787702..2788337) 1 NC_010473.1 hypothetical protein 2788337 yfhB 6060552 yfhB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731490.1 2787702 R 316385 CDS YP_001731491.1 170082171 6060590 2788546..2789394 1 NC_010473.1 putative DNA-binding transcriptional regulator 2789394 yfhH 6060590 yfhH Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001731491.1 2788546 D 316385 CDS YP_001731492.1 170082172 6060602 2789450..2789710 1 NC_010473.1 4Fe-4S binding protein 2789710 yfhL 6060602 yfhL Escherichia coli str. K-12 substr. DH10B 4Fe-4S binding protein YP_001731492.1 2789450 D 316385 CDS YP_001731493.1 170082173 6060622 complement(2790785..2791516) 1 NC_010473.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2791516 pdxJ 6060622 pdxJ Escherichia coli str. K-12 substr. DH10B pyridoxine 5'-phosphate synthase YP_001731493.1 2790785 R 316385 CDS YP_001731494.1 170082174 6060631 complement(2791528..2792256) 1 NC_010473.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2792256 recO 6060631 recO Escherichia coli str. K-12 substr. DH10B DNA repair protein RecO YP_001731494.1 2791528 R 316385 CDS YP_001731495.1 170082175 6060633 complement(2792268..2793173) 1 NC_010473.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2793173 era 6060633 era Escherichia coli str. K-12 substr. DH10B GTP-binding protein Era YP_001731495.1 2792268 R 316385 CDS YP_001731496.1 170082176 6060636 complement(2793170..2793850) 1 NC_010473.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2793850 rnc 6060636 rnc Escherichia coli str. K-12 substr. DH10B ribonuclease III YP_001731496.1 2793170 R 316385 CDS YP_001731497.1 170082177 6060642 complement(2794122..2795096) 1 NC_010473.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2795096 lepB 6060642 lepB Escherichia coli str. K-12 substr. DH10B signal peptidase I YP_001731497.1 2794122 R 316385 CDS YP_001731498.1 170082178 6060657 complement(2795112..2796911) 1 NC_010473.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2796911 lepA 6060657 lepA Escherichia coli str. K-12 substr. DH10B GTP-binding protein LepA YP_001731498.1 2795112 R 316385 CDS YP_001731499.1 170082179 6060663 complement(2797109..2797588) 1 NC_010473.1 protein involved in reduction of the SoxR iron-sulfur cluster; involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2797588 rseC 6060663 rseC Escherichia coli str. K-12 substr. DH10B SoxR reducing system protein RseC YP_001731499.1 2797109 R 316385 CDS YP_001731500.1 170082180 6060665 complement(2797585..2798541) 1 NC_010473.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2798541 rseB 6060665 rseB Escherichia coli str. K-12 substr. DH10B periplasmic negative regulator of sigmaE YP_001731500.1 2797585 R 316385 CDS YP_001731501.1 170082181 6060667 complement(2798541..2799191) 1 NC_010473.1 anti-RNA polymerase sigma factor SigE 2799191 rseA 6060667 rseA Escherichia coli str. K-12 substr. DH10B anti-RNA polymerase sigma factor SigE YP_001731501.1 2798541 R 316385 CDS YP_001731502.1 170082182 6060683 complement(2799224..2799799) 1 NC_010473.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2799799 rpoE 6060683 rpoE Escherichia coli str. K-12 substr. DH10B RNA polymerase sigma factor RpoE YP_001731502.1 2799224 R 316385 CDS YP_001731503.1 170082183 6060695 2800207..2801829 1 NC_010473.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2801829 nadB 6060695 nadB Escherichia coli str. K-12 substr. DH10B L-aspartate oxidase YP_001731503.1 2800207 D 316385 CDS YP_001731504.1 170082184 6060703 complement(2801814..2802551) 1 NC_010473.1 S-adenosyl-L-methionine-dependent methyltransferase 2802551 yfiC 6060703 yfiC Escherichia coli str. K-12 substr. DH10B S-adenosyl-L-methionine-dependent methyltransferase YP_001731504.1 2801814 R 316385 CDS YP_001731505.1 170082185 6060710 2802683..2804017 1 NC_010473.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2804017 srmB 6060710 srmB Escherichia coli str. K-12 substr. DH10B ATP-dependent RNA helicase SrmB YP_001731505.1 2802683 D 316385 CDS YP_001731506.1 170082186 6060729 complement(2804226..2805107) 1 NC_010473.1 DNA-binding transcriptional regulator 2805107 yfiE 6060729 yfiE Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731506.1 2804226 R 316385 CDS YP_001731507.1 170082187 6060738 2805210..2805797 1 NC_010473.1 neutral amino-acid efflux protein 2805797 yfiK 6060738 yfiK Escherichia coli str. K-12 substr. DH10B neutral amino-acid efflux protein YP_001731507.1 2805210 D 316385 CDS YP_001731508.1 170082188 6060746 complement(2805853..2806236) 1 NC_010473.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2806236 yfiD 6060746 yfiD Escherichia coli str. K-12 substr. DH10B autonomous glycyl radical cofactor GrcA YP_001731508.1 2805853 R 316385 CDS YP_001731509.1 170082189 6060754 2806541..2807230 1 NC_010473.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2807230 ung 6060754 ung Escherichia coli str. K-12 substr. DH10B uracil-DNA glycosylase YP_001731509.1 2806541 D 316385 CDS YP_001731510.1 170082190 6060763 complement(2807278..2808315) 1 NC_010473.1 putative methyltransferase 2808315 yfiF 6060763 yfiF Escherichia coli str. K-12 substr. DH10B putative methyltransferase YP_001731510.1 2807278 R 316385 CDS YP_001731511.1 170082191 6060770 2808522..2808941 1 NC_010473.1 thioredoxin 2 2808941 trxC 6060770 trxC Escherichia coli str. K-12 substr. DH10B thioredoxin 2 YP_001731511.1 2808522 D 316385 CDS YP_001731512.1 170082192 6060082 2809010..2809708 1 NC_010473.1 hypothetical protein 2809708 yfiP 6060082 yfiP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731512.1 2809010 D 316385 CDS YP_001731513.1 170082193 6060089 2809740..2812400 1 NC_010473.1 fused acyl-CoA synthetase: NAD(P)-binding subunit; ATP-binding subunit 2812400 yfiQ 6060089 yfiQ Escherichia coli str. K-12 substr. DH10B fused acyl-CoA synthetase: NAD(P)-binding subunit; ATP-binding subunit YP_001731513.1 2809740 D 316385 CDS YP_001731514.1 170082194 6060093 2812514..2813869 1 NC_010473.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2813869 pssA 6060093 pssA Escherichia coli str. K-12 substr. DH10B phosphatidylserine synthase YP_001731514.1 2812514 D 316385 CDS YP_001731515.1 170082195 6060095 2813966..2814238 1 NC_010473.1 hypothetical protein 2814238 yfiM 6060095 yfiM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731515.1 2813966 D 316385 CDS YP_001731516.1 170082196 6060096 complement(2814235..2815533) 1 NC_010473.1 alpha-ketoglutarate transporter 2815533 kgtP 6060096 kgtP Escherichia coli str. K-12 substr. DH10B alpha-ketoglutarate transporter YP_001731516.1 2814235 R 316385 CDS YP_001731517.1 170082197 6060330 complement(2821387..2823960) 1 NC_010473.1 protein disaggregation chaperone 2823960 clpB 6060330 clpB Escherichia coli str. K-12 substr. DH10B protein disaggregation chaperone YP_001731517.1 2821387 R 316385 CDS YP_001731518.1 170082198 6060795 complement(2824090..2824821) 1 NC_010473.1 hypothetical protein 2824821 yfiH 6060795 yfiH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731518.1 2824090 R 316385 CDS YP_001731519.1 170082199 6060808 complement(2824818..2825798) 1 NC_010473.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 2825798 rluD 6060808 rluD Escherichia coli str. K-12 substr. DH10B 23S rRNA pseudouridine synthase D YP_001731519.1 2824818 R 316385 CDS YP_001731520.1 170082200 6060810 2825933..2826670 1 NC_010473.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2826670 yfiO 6060810 yfiO Escherichia coli str. K-12 substr. DH10B outer membrane protein assembly complex subunit YfiO YP_001731520.1 2825933 D 316385 CDS YP_001731521.1 170082201 6060815 2826941..2827282 1 NC_010473.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2827282 yfiA 6060815 yfiA Escherichia coli str. K-12 substr. DH10B translation inhibitor protein RaiA YP_001731521.1 2826941 D 316385 CDS YP_001731523.1 170082203 6060836 2827532..2828692 1 NC_010473.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2828692 pheA 6060836 pheA Escherichia coli str. K-12 substr. DH10B bifunctional chorismate mutase/prephenate dehydratase YP_001731523.1 2827532 D 316385 CDS YP_001731524.1 170082204 6060839 complement(2828735..2829856) 1 NC_010473.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 2829856 tyrA 6060839 tyrA Escherichia coli str. K-12 substr. DH10B bifunctional chorismate mutase/prephenate dehydrogenase YP_001731524.1 2828735 R 316385 CDS YP_001731525.1 170082205 6060851 complement(2829867..2830937) 1 NC_010473.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2830937 aroF 6060851 aroF Escherichia coli str. K-12 substr. DH10B phospho-2-dehydro-3-deoxyheptonate aldolase YP_001731525.1 2829867 R 316385 CDS YP_001731526.1 170082206 6060853 2831147..2831512 1 NC_010473.1 hypothetical protein 2831512 yfiL 6060853 yfiL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731526.1 2831147 D 316385 CDS YP_001731527.1 170082207 6060855 2831662..2832180 1 NC_010473.1 hypothetical protein 2832180 yfiR 6060855 yfiR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731527.1 2831662 D 316385 CDS YP_001731528.1 170082208 6060856 2832170..2833396 1 NC_010473.1 hypothetical protein 2833396 yfiN 6060856 yfiN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731528.1 2832170 D 316385 CDS YP_001731529.1 170082209 6060857 2833412..2833894 1 NC_010473.1 putative outer membrane lipoprotein 2833894 yfiB 6060857 yfiB Escherichia coli str. K-12 substr. DH10B putative outer membrane lipoprotein YP_001731529.1 2833412 D 316385 CDS YP_001731530.1 170082210 6060858 complement(2833970..2834317) 1 NC_010473.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2834317 rplS 6060858 rplS Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L19 YP_001731530.1 2833970 R 316385 CDS YP_001731531.1 170082211 6060859 complement(2834359..2835126) 1 NC_010473.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 2835126 trmD 6060859 trmD Escherichia coli str. K-12 substr. DH10B tRNA (guanine-N(1)-)-methyltransferase YP_001731531.1 2834359 R 316385 CDS YP_001731532.1 170082212 6060884 complement(2835157..2835705) 1 NC_010473.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2835705 rimM 6060884 rimM Escherichia coli str. K-12 substr. DH10B 16S rRNA-processing protein RimM YP_001731532.1 2835157 R 316385 CDS YP_001731533.1 170082213 6060887 complement(2835724..2835972) 1 NC_010473.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2835972 rpsP 6060887 rpsP Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S16 YP_001731533.1 2835724 R 316385 CDS YP_001731534.1 170082214 6060891 complement(2836221..2837582) 1 NC_010473.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 2837582 ffh 6060891 ffh Escherichia coli str. K-12 substr. DH10B signal recognition particle protein YP_001731534.1 2836221 R 316385 CDS YP_001731535.1 170082215 6060894 2838561..2839847 1 NC_010473.1 hypothetical protein 2839847 yfjD 6060894 yfjD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731535.1 2838561 D 316385 CDS YP_001731536.1 170082216 6060900 complement(2839902..2840495) 1 NC_010473.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 2840495 grpE 6060900 grpE Escherichia coli str. K-12 substr. DH10B heat shock protein GrpE YP_001731536.1 2839902 R 316385 CDS YP_001731537.1 170082217 6060907 2840618..2841496 1 NC_010473.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2841496 ppnK 6060907 ppnK Escherichia coli str. K-12 substr. DH10B inorganic polyphosphate/ATP-NAD kinase YP_001731537.1 2840618 D 316385 CDS YP_001731538.1 170082218 6060914 2841582..2843243 1 NC_010473.1 recombination and repair protein 2843243 recN 6060914 recN Escherichia coli str. K-12 substr. DH10B recombination and repair protein YP_001731538.1 2841582 D 316385 CDS YP_001731539.1 170082219 6060934 2843392..2843733 1 NC_010473.1 hypothetical protein 2843733 smpA 6060934 smpA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731539.1 2843392 D 316385 CDS YP_001731540.1 170082220 6060935 complement(2843795..2844085) 1 NC_010473.1 hypothetical protein 2844085 yfjF 6060935 yfjF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731540.1 2843795 R 316385 CDS YP_001731541.1 170082221 6060946 complement(2844075..2844551) 1 NC_010473.1 hypothetical protein 2844551 yfjG 6060946 yfjG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731541.1 2844075 R 316385 CDS YP_001731542.1 170082222 6060947 2844683..2845165 1 NC_010473.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2845165 smpB 6060947 smpB Escherichia coli str. K-12 substr. DH10B SsrA-binding protein YP_001731542.1 2844683 D 316385 CDS YP_001731543.1 170082223 6060353 complement(2847431..2848387) 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2848387 yfjH 6060353 yfjH Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731543.1 2847431 R 316385 CDS YP_001731544.1 170082224 6060961 2848431..2848643 1 NC_010473.1 CP4-57 prophage; DNA-binding transcriptional activator 2848643 alpA 6060961 alpA Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; DNA-binding transcriptional activator YP_001731544.1 2848431 D 316385 CDS YP_001731545.1 170082225 6060962 2848772..2850181 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2850181 yfjI 6060962 yfjI Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731545.1 2848772 D 316385 CDS YP_001731546.1 170082226 6060963 2850334..2850960 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2850960 yfjJ 6060963 yfjJ Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731546.1 2850334 D 316385 CDS YP_001731547.1 170082227 6060970 complement(2851138..2853327) 1 NC_010473.1 CP4-57 prophage; protein 2853327 yfjK 6060970 yfjK Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; protein YP_001731547.1 2851138 R 316385 CDS YP_001731548.1 170082228 6060971 complement(2853324..2854940) 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2854940 yfjL 6060971 yfjL Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731548.1 2853324 R 316385 CDS YP_001731549.1 170082229 6060991 complement(2855300..2855563) 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2855563 yfjM 6060991 yfjM Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731549.1 2855300 R 316385 CDS YP_001731550.1 170082230 6060992 2855705..2856778 1 NC_010473.1 CP4-57 prophage; RNase LS 2856778 yfjN 6060992 yfjN Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; RNase LS YP_001731550.1 2855705 D 316385 CDS YP_001731551.1 170082231 6060995 2856771..2857142 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2857142 yfjO 6060995 yfjO Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731551.1 2856771 D 316385 CDS YP_001731552.1 170082232 6060996 2857497..2858360 1 NC_010473.1 CP4-57 prophage; GTP-binding protein 2858360 yfjP 6060996 yfjP Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; GTP-binding protein YP_001731552.1 2857497 D 316385 CDS YP_001731553.1 170082233 6061007 2858452..2859273 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2859273 yfjQ 6061007 yfjQ Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731553.1 2858452 D 316385 CDS YP_001731554.1 170082234 6061009 2859490..2860191 1 NC_010473.1 CP4-57 prophage; DNA-binding transcriptional regulator 2860191 yfjR 6061009 yfjR Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; DNA-binding transcriptional regulator YP_001731554.1 2859490 D 316385 CDS YP_001731555.1 170082235 6061011 2860232..2860468 1 NC_010473.1 CP4-57 prophage; inner membrane protein 2860468 ypjK 6061011 ypjK Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; inner membrane protein YP_001731555.1 2860232 D 316385 CDS YP_001731556.1 170082236 6061015 2860468..2860911 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2860911 yfjS 6061015 yfjS Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731556.1 2860468 D 316385 CDS YP_001731557.1 170082237 6061018 2860935..2861402 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2861402 yfjT 6061018 yfjT Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731557.1 2860935 D 316385 CDS YP_001731558.1 170082238 6061031 complement(2861627..2861941) 1 NC_010473.1 CP4-57 prophage; protein 2861941 yfjU 6061031 yfjU Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; protein YP_001731558.1 2861627 R 316385 CDS YP_001731559.1 170082239 6061039 complement(2861954..2862472) 1 NC_010473.1 CP4-57 prophage; inner membrane protein 2862472 ypjL 6061039 ypjL Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; inner membrane protein YP_001731559.1 2861954 R 316385 CDS YP_001731560.1 170082240 6061048 complement(2862623..2862823) 1 NC_010473.1 CP4-57 prophage; hypothetical protein 2862823 yfjV 6061048 yfjV Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; hypothetical protein YP_001731560.1 2862623 R 316385 CDS YP_001731561.1 170082241 6061058 2863105..2864808 1 NC_010473.1 CP4-57 prophage; inner membrane protein 2864808 yfjW 6061058 yfjW Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; inner membrane protein YP_001731561.1 2863105 D 316385 CDS YP_001731562.1 170082242 6061062 2865706..2866164 1 NC_010473.1 CP4-57 prophage; antirestriction protein 2866164 yfjX 6061062 yfjX Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; antirestriction protein YP_001731562.1 2865706 D 316385 CDS YP_001731563.1 170082243 6061069 2866173..2866655 1 NC_010473.1 CP4-57 prophage; DNA repair protein 2866655 yfjY 6061069 yfjY Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; DNA repair protein YP_001731563.1 2866173 D 316385 CDS YP_001731564.1 170082244 6061075 2866664..2866864 1 NC_010473.1 hypothetical protein 2866864 ypjJ 6061075 ypjJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731564.1 2866664 D 316385 CDS YP_001731565.1 170082245 6061082 2866902..2867219 1 NC_010473.1 CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system 2867219 yfjZ 6061082 yfjZ Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system YP_001731565.1 2866902 D 316385 CDS YP_001731566.1 170082246 6061088 2867240..2867569 1 NC_010473.1 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system 2867569 ypjF 6061088 ypjF Escherichia coli str. K-12 substr. DH10B CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system YP_001731566.1 2867240 D 316385 CDS YP_001731567.1 170082247 6061534 2878772..2879749 1 NC_010473.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2879749 ygaT 6061534 ygaT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731567.1 2878772 D 316385 CDS YP_001731568.1 170082248 6061109 2879769..2881037 1 NC_010473.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2881037 ygaF 6061109 ygaF Escherichia coli str. K-12 substr. DH10B hydroxyglutarate oxidase YP_001731568.1 2879769 D 316385 CDS YP_001731569.1 170082249 6061113 2882522..2883802 1 NC_010473.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2883802 gabT 6061113 gabT Escherichia coli str. K-12 substr. DH10B 4-aminobutyrate aminotransferase YP_001731569.1 2882522 D 316385 CDS YP_001731570.1 170082250 6061128 2884040..2885440 1 NC_010473.1 gamma-aminobutyrate transporter 2885440 gabP 6061128 gabP Escherichia coli str. K-12 substr. DH10B gamma-aminobutyrate transporter YP_001731570.1 2884040 D 316385 CDS YP_001731571.1 170082251 6061132 2885461..2886123 1 NC_010473.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2886123 csiR 6061132 csiR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator CsiR YP_001731571.1 2885461 D 316385 CDS YP_001731572.1 170082252 6061134 complement(2886124..2886573) 1 NC_010473.1 LysM domain/BON superfamily protein 2886573 ygaU 6061134 ygaU Escherichia coli str. K-12 substr. DH10B LysM domain/BON superfamily protein YP_001731572.1 2886124 R 316385 CDS YP_001731573.1 170082253 6061144 complement(2886657..2886815) 1 NC_010473.1 hypothetical protein 2886815 yqaE 6061144 yqaE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731573.1 2886657 R 316385 CDS YP_001731574.1 170082254 6061152 2886998..2887297 1 NC_010473.1 DNA-binding transcriptional regulator 2887297 ygaV 6061152 ygaV Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731574.1 2886998 D 316385 CDS YP_001731575.1 170082255 6061154 2887307..2887831 1 NC_010473.1 inner membrane protein with hydrolase activity 2887831 ygaP 6061154 ygaP Escherichia coli str. K-12 substr. DH10B inner membrane protein with hydrolase activity YP_001731575.1 2887307 D 316385 CDS YP_001731576.1 170082256 6061158 complement(2887878..2888282) 1 NC_010473.1 DNA binding protein 2888282 stpA 6061158 stpA Escherichia coli str. K-12 substr. DH10B DNA binding protein YP_001731576.1 2887878 R 316385 CDS YP_001731577.1 170082257 6061160 2888951..2889400 1 NC_010473.1 inner membrane protein 2889400 ygaW 6061160 ygaW Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731577.1 2888951 D 316385 CDS YP_001731578.1 170082258 6061161 complement(2889437..2889781) 1 NC_010473.1 hypothetical protein 2889781 ygaC 6061161 ygaC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731578.1 2889437 R 316385 CDS YP_001731579.1 170082259 6061169 2890510..2890755 1 NC_010473.1 glutaredoxin-like protein 2890755 nrdH 6061169 nrdH Escherichia coli str. K-12 substr. DH10B glutaredoxin-like protein YP_001731579.1 2890510 D 316385 CDS YP_001731580.1 170082260 6061171 2890752..2891162 1 NC_010473.1 protein that stimulates ribonucleotide reduction; in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2891162 nrdI 6061171 nrdI Escherichia coli str. K-12 substr. DH10B ribonucleotide reductase stimulatory protein YP_001731580.1 2890752 D 316385 CDS YP_001731581.1 170082261 6061178 2891135..2893279 1 NC_010473.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2893279 nrdE 6061178 nrdE Escherichia coli str. K-12 substr. DH10B ribonucleotide-diphosphate reductase subunit alpha YP_001731581.1 2891135 D 316385 CDS YP_001731582.1 170082262 6061179 2893289..2894248 1 NC_010473.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2894248 nrdF 6061179 nrdF Escherichia coli str. K-12 substr. DH10B ribonucleotide-diphosphate reductase subunit beta YP_001731582.1 2893289 D 316385 CDS YP_001731583.1 170082263 6061182 2896574..2897638 1 NC_010473.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2897638 proW 6061182 proW Escherichia coli str. K-12 substr. DH10B glycine betaine transporter membrane protein YP_001731583.1 2896574 D 316385 CDS YP_001731584.1 170082264 6061186 2897696..2898688 1 NC_010473.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2898688 proX 6061186 proX Escherichia coli str. K-12 substr. DH10B glycine betaine transporter periplasmic subunit YP_001731584.1 2897696 D 316385 CDS YP_001731585.1 170082265 6058950 2900181..2900918 1 NC_010473.1 transporter 2900918 ygaZ 6058950 ygaZ Escherichia coli str. K-12 substr. DH10B transporter YP_001731585.1 2900181 D 316385 CDS YP_001731586.1 170082266 6061196 2900908..2901243 1 NC_010473.1 hypothetical protein 2901243 ygaH 6061196 ygaH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731586.1 2900908 D 316385 CDS YP_001731587.1 170082267 6061199 2901991..2903163 1 NC_010473.1 multidrug efflux system 2903163 emrA 6061199 emrA Escherichia coli str. K-12 substr. DH10B multidrug efflux system YP_001731587.1 2901991 D 316385 CDS YP_001731588.1 170082268 6061206 2903180..2904718 1 NC_010473.1 multidrug efflux system protein 2904718 emrB 6061206 emrB Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein YP_001731588.1 2903180 D 316385 CDS YP_001731589.1 170082269 6061207 complement(2904782..2905297) 1 NC_010473.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2905297 luxS 6061207 luxS Escherichia coli str. K-12 substr. DH10B S-ribosylhomocysteinase YP_001731589.1 2904782 R 316385 CDS YP_001731590.1 170082270 6060402 complement(2905447..2907003) 1 NC_010473.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 2907003 gshA 6060402 gshA Escherichia coli str. K-12 substr. DH10B glutamate--cysteine ligase YP_001731590.1 2905447 R 316385 CDS YP_001731591.1 170082271 6061230 complement(2907076..2907504) 1 NC_010473.1 inner membrane protein 2907504 yqaA 6061230 yqaA Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731591.1 2907076 R 316385 CDS YP_001731592.1 170082272 6061231 complement(2907501..2908067) 1 NC_010473.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 2908067 yqaB 6061231 yqaB Escherichia coli str. K-12 substr. DH10B fructose-1-phosphatase YP_001731592.1 2907501 R 316385 CDS YP_001731593.1 170082273 6061929 complement(2909525..2909710) 1 NC_010473.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 2909710 csrA 6061929 csrA Escherichia coli str. K-12 substr. DH10B carbon storage regulator YP_001731593.1 2909525 R 316385 CDS YP_001731594.1 170082274 6061256 complement(2909945..2912575) 1 NC_010473.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2912575 alaS 6061256 alaS Escherichia coli str. K-12 substr. DH10B alanyl-tRNA synthetase YP_001731594.1 2909945 R 316385 CDS YP_001731595.1 170082275 6061279 complement(2912703..2913203) 1 NC_010473.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2913203 recX 6061279 recX Escherichia coli str. K-12 substr. DH10B recombination regulator RecX YP_001731595.1 2912703 R 316385 CDS YP_001731596.1 170082276 6061285 complement(2914413..2914910) 1 NC_010473.1 competence damage-inducible protein A 2914910 ygaD 6061285 ygaD Escherichia coli str. K-12 substr. DH10B competence damage-inducible protein A YP_001731596.1 2914413 R 316385 CDS YP_001731597.1 170082277 6061287 complement(2915055..2916140) 1 NC_010473.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 2916140 mltB 6061287 mltB Escherichia coli str. K-12 substr. DH10B murein hydrolase B YP_001731597.1 2915055 R 316385 CDS YP_001731598.1 170082278 6061295 2916396..2916959 1 NC_010473.1 PTS system glucitol/sorbitol-specific transporter subunit IIC 2916959 srlA 6061295 srlA Escherichia coli str. K-12 substr. DH10B PTS system glucitol/sorbitol-specific transporter subunit IIC YP_001731598.1 2916396 D 316385 CDS YP_001731599.1 170082279 6061298 2916956..2917915 1 NC_010473.1 glucitol/sorbitol-specific enzyme IIB component of PTS 2917915 srlE 6061298 srlE Escherichia coli str. K-12 substr. DH10B glucitol/sorbitol-specific enzyme IIB component of PTS YP_001731599.1 2916956 D 316385 CDS YP_001731600.1 170082280 6061303 2917926..2918297 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2918297 srlB 6061303 srlB Escherichia coli str. K-12 substr. DH10B PTS system glucitol/sorbitol-specific transporter subunit IIA YP_001731600.1 2917926 D 316385 CDS YP_001731601.1 170082281 6061308 2918301..2919080 1 NC_010473.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2919080 srlD 6061308 srlD Escherichia coli str. K-12 substr. DH10B sorbitol-6-phosphate dehydrogenase YP_001731601.1 2918301 D 316385 CDS YP_001731602.1 170082282 6061314 2919185..2919544 1 NC_010473.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2919544 gutM 6061314 gutM Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator GutM YP_001731602.1 2919185 D 316385 CDS YP_001731603.1 170082283 6061315 2919611..2920384 1 NC_010473.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2920384 srlR 6061315 srlR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor SrlR YP_001731603.1 2919611 D 316385 CDS YP_001731604.1 170082284 6061326 2920377..2921342 1 NC_010473.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2921342 gutQ 6061326 gutQ Escherichia coli str. K-12 substr. DH10B D-arabinose 5-phosphate isomerase YP_001731604.1 2920377 D 316385 CDS YP_001731605.1 170082285 6061332 complement(2921339..2922853) 1 NC_010473.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 2922853 norR 6061332 norR Escherichia coli str. K-12 substr. DH10B anaerobic nitric oxide reductase transcriptional regulator YP_001731605.1 2921339 R 316385 CDS YP_001731606.1 170082286 6061334 2923040..2924479 1 NC_010473.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2924479 norV 6061334 norV Escherichia coli str. K-12 substr. DH10B anaerobic nitric oxide reductase flavorubredoxin YP_001731606.1 2923040 D 316385 CDS YP_001731607.1 170082287 6061342 2924476..2925609 1 NC_010473.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2925609 norW 6061342 norW Escherichia coli str. K-12 substr. DH10B nitric oxide reductase YP_001731607.1 2924476 D 316385 CDS YP_001731608.1 170082288 6061358 complement(2925737..2927989) 1 NC_010473.1 carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases 2927989 hypF 6061358 hypF Escherichia coli str. K-12 substr. DH10B carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases YP_001731608.1 2925737 R 316385 CDS YP_001731609.1 170082289 6061361 complement(2928142..2928669) 1 NC_010473.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 2928669 hydN 6061361 hydN Escherichia coli str. K-12 substr. DH10B electron transport protein HydN YP_001731609.1 2928142 R 316385 CDS YP_001731610.1 170082290 6061363 complement(2928818..2929831) 1 NC_010473.1 DNA-binding transcriptional repressor 2929831 ascG 6061363 ascG Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor YP_001731610.1 2928818 R 316385 CDS YP_001731611.1 170082291 6061377 2930088..2931545 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 2931545 ascF 6061377 ascF Escherichia coli str. K-12 substr. DH10B PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_001731611.1 2930088 D 316385 CDS YP_001731612.1 170082292 6061380 2931554..2932978 1 NC_010473.1 cryptic 6-phospho-beta-glucosidase 2932978 ascB 6061380 ascB Escherichia coli str. K-12 substr. DH10B cryptic 6-phospho-beta-glucosidase YP_001731612.1 2931554 D 316385 CDS YP_001731613.1 170082293 6061389 complement(2933137..2933607) 1 NC_010473.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 2933607 hycI 6061389 hycI Escherichia coli str. K-12 substr. DH10B hydrogenase 3 maturation protease YP_001731613.1 2933137 R 316385 CDS YP_001731614.1 170082294 6061392 complement(2933600..2934010) 1 NC_010473.1 protein required for maturation of hydrogenase 3; protein Hycprotein H 2934010 hycH 6061392 hycH Escherichia coli str. K-12 substr. DH10B protein Hycprotein H YP_001731614.1 2933600 R 316385 CDS YP_001731615.1 170082295 6061399 complement(2934007..2934774) 1 NC_010473.1 hydrogenase 3 and formate hydrogenase complex, HycG subunit 2934774 hycG 6061399 hycG Escherichia coli str. K-12 substr. DH10B hydrogenase 3 and formate hydrogenase complex, HycG subunit YP_001731615.1 2934007 R 316385 CDS YP_001731616.1 170082296 6061413 complement(2934774..2935316) 1 NC_010473.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 2935316 hycF 6061413 hycF Escherichia coli str. K-12 substr. DH10B formate hydrogenlyase complex iron-sulfur subunit YP_001731616.1 2934774 R 316385 CDS YP_001731617.1 170082297 6061425 complement(2935326..2937035) 1 NC_010473.1 hydrogenase 3, large subunit 2937035 hycE 6061425 hycE Escherichia coli str. K-12 substr. DH10B hydrogenase 3, large subunit YP_001731617.1 2935326 R 316385 CDS YP_001731618.1 170082298 6061439 complement(2937053..2937976) 1 NC_010473.1 hydrogenase 3, membrane subunit 2937976 hycD 6061439 hycD Escherichia coli str. K-12 substr. DH10B hydrogenase 3, membrane subunit YP_001731618.1 2937053 R 316385 CDS YP_001731619.1 170082299 6061441 complement(2937979..2939805) 1 NC_010473.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 2939805 hycC 6061441 hycC Escherichia coli str. K-12 substr. DH10B formate hydrogenlyase subunit 3 YP_001731619.1 2937979 R 316385 CDS YP_001731620.1 170082300 6061445 complement(2939802..2940413) 1 NC_010473.1 hydrogenase 3, Fe-S subunit 2940413 hycB 6061445 hycB Escherichia coli str. K-12 substr. DH10B hydrogenase 3, Fe-S subunit YP_001731620.1 2939802 R 316385 CDS YP_001731621.1 170082301 6061446 complement(2940538..2940999) 1 NC_010473.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 2940999 hycA 6061446 hycA Escherichia coli str. K-12 substr. DH10B formate hydrogenlyase regulatory protein HycA YP_001731621.1 2940538 R 316385 CDS YP_001731622.1 170082302 6061460 2941211..2941561 1 NC_010473.1 protein involved in nickel insertion into hydrogenases 3; plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 2941561 hypA 6061460 hypA Escherichia coli str. K-12 substr. DH10B hydrogenase nickel incorporation protein YP_001731622.1 2941211 D 316385 CDS YP_001731623.1 170082303 6061463 2941565..2942437 1 NC_010473.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 2942437 hypB 6061463 hypB Escherichia coli str. K-12 substr. DH10B hydrogenase nickel incorporation protein HypB YP_001731623.1 2941565 D 316385 CDS YP_001731624.1 170082304 6061465 2942428..2942700 1 NC_010473.1 protein required for maturation of hydrogenases 1 and 3; HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 2942700 hypC 6061465 hypC Escherichia coli str. K-12 substr. DH10B hydrogenase assembly chaperone YP_001731624.1 2942428 D 316385 CDS YP_001731625.1 170082305 6061476 2942700..2943821 1 NC_010473.1 protein required for maturation of hydrogenases; hypothetical protein 2943821 hypD 6061476 hypD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731625.1 2942700 D 316385 CDS YP_001731626.1 170082306 6061480 2943860..2944828 1 NC_010473.1 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 2944828 hypE 6061480 hypE Escherichia coli str. K-12 substr. DH10B carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein YP_001731626.1 2943860 D 316385 CDS YP_001731627.1 170082307 6061481 2944902..2946980 1 NC_010473.1 DNA-binding transcriptional activator 2946980 fhlA 6061481 fhlA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator YP_001731627.1 2944902 D 316385 CDS YP_001731628.1 170082308 6061484 complement(2947017..2947370) 1 NC_010473.1 hypothetical protein 2947370 ygbA 6061484 ygbA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731628.1 2947017 R 316385 CDS YP_001731629.1 170082309 6061488 2947657..2950218 1 NC_010473.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2950218 mutS 6061488 mutS Escherichia coli str. K-12 substr. DH10B DNA mismatch repair protein MutS YP_001731629.1 2947657 D 316385 CDS YP_001731630.1 170082310 6061503 2950324..2950980 1 NC_010473.1 serine/threonine-specific protein phosphatase 2 2950980 pphB 6061503 pphB Escherichia coli str. K-12 substr. DH10B serine/threonine-specific protein phosphatase 2 YP_001731630.1 2950324 D 316385 CDS YP_001731631.1 170082311 6061508 complement(2951031..2951828) 1 NC_010473.1 DNA-binding transcriptional regulator 2951828 ygbI 6061508 ygbI Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731631.1 2951031 R 316385 CDS YP_001731632.1 170082312 6061513 2951994..2952902 1 NC_010473.1 dehydrogenase 2952902 ygbJ 6061513 ygbJ Escherichia coli str. K-12 substr. DH10B dehydrogenase YP_001731632.1 2951994 D 316385 CDS YP_001731633.1 170082313 6061515 2952899..2954065 1 NC_010473.1 hypothetical protein 2954065 ygbK 6061515 ygbK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731633.1 2952899 D 316385 CDS YP_001731634.1 170082314 6061523 2954800..2955576 1 NC_010473.1 hypothetical protein 2955576 ygbM 6061523 ygbM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731634.1 2954800 D 316385 CDS YP_001731635.1 170082315 6061526 2955665..2957029 1 NC_010473.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 2957029 ygbN 6061526 ygbN Escherichia coli str. K-12 substr. DH10B inner membrane permease YgbN YP_001731635.1 2955665 D 316385 CDS YP_001731636.1 170082316 6061531 complement(2957123..2958115) 1 NC_010473.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 2958115 rpoS 6061531 rpoS Escherichia coli str. K-12 substr. DH10B RNA polymerase sigma factor RpoS YP_001731636.1 2957123 R 316385 CDS YP_001731637.1 170082317 6058878 complement(2958178..2959317) 1 NC_010473.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 2959317 nlpD 6058878 nlpD Escherichia coli str. K-12 substr. DH10B lipoprotein NlpD YP_001731637.1 2958178 R 316385 CDS YP_001731638.1 170082318 6061536 complement(2959457..2960083) 1 NC_010473.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 2960083 pcm 6061536 pcm Escherichia coli str. K-12 substr. DH10B protein-L-isoaspartate O-methyltransferase YP_001731638.1 2959457 R 316385 CDS YP_001731639.1 170082319 6061537 complement(2960077..2960838) 1 NC_010473.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 2960838 surE 6061537 surE Escherichia coli str. K-12 substr. DH10B stationary phase survival protein SurE YP_001731639.1 2960077 R 316385 CDS YP_001731640.1 170082320 6061547 complement(2960819..2961868) 1 NC_010473.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 2961868 truD 6061547 truD Escherichia coli str. K-12 substr. DH10B tRNA pseudouridine synthase D YP_001731640.1 2960819 R 316385 CDS YP_001731641.1 170082321 6061551 complement(2961865..2962344) 1 NC_010473.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2962344 ispF 6061551 ispF Escherichia coli str. K-12 substr. DH10B 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001731641.1 2961865 R 316385 CDS YP_001731642.1 170082322 6061553 complement(2962344..2963054) 1 NC_010473.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2963054 ispD 6061553 ispD Escherichia coli str. K-12 substr. DH10B 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001731642.1 2962344 R 316385 CDS YP_001731643.1 170082323 6061554 complement(2963073..2963384) 1 NC_010473.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 2963384 ftsB 6061554 ftsB Escherichia coli str. K-12 substr. DH10B cell division protein FtsB YP_001731643.1 2963073 R 316385 CDS YP_001731644.1 170082324 6061560 complement(2963578..2963901) 1 NC_010473.1 hypothetical protein 2963901 ygbE 6061560 ygbE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731644.1 2963578 R 316385 CDS YP_001731645.1 170082325 6061563 complement(2963951..2964556) 1 NC_010473.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 2964556 cysC 6061563 cysC Escherichia coli str. K-12 substr. DH10B adenylylsulfate kinase YP_001731645.1 2963951 R 316385 CDS YP_001731646.1 170082326 6061564 complement(2964556..2965983) 1 NC_010473.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 2965983 cysN 6061564 cysN Escherichia coli str. K-12 substr. DH10B sulfate adenylyltransferase subunit 1 YP_001731646.1 2964556 R 316385 CDS YP_001731647.1 170082327 6061566 complement(2965985..2966893) 1 NC_010473.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2966893 cysD 6061566 cysD Escherichia coli str. K-12 substr. DH10B sulfate adenylyltransferase subunit 2 YP_001731647.1 2965985 R 316385 CDS YP_001731648.1 170082328 6061572 2967145..2968182 1 NC_010473.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 2968182 iap 6061572 iap Escherichia coli str. K-12 substr. DH10B alkaline phosphatase isozyme conversion aminopeptidase YP_001731648.1 2967145 D 316385 CDS YP_001731649.1 170082329 6062411 complement(2969133..2969417) 1 NC_010473.1 hypothetical protein 2969417 ygbF 6062411 ygbF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731649.1 2969133 R 316385 CDS YP_001731650.1 170082330 6061577 complement(2969419..2970336) 1 NC_010473.1 hypothetical protein 2970336 ygbT 6061577 ygbT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731650.1 2969419 R 316385 CDS YP_001731651.1 170082331 6061582 complement(2970352..2970951) 1 NC_010473.1 hypothetical protein 2970951 ygcH 6061582 ygcH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731651.1 2970352 R 316385 CDS YP_001731652.1 170082332 6061583 complement(2970938..2971612) 1 NC_010473.1 hypothetical protein 2971612 ygcI 6061583 ygcI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731652.1 2970938 R 316385 CDS YP_001731653.1 170082333 6061588 complement(2971615..2972706) 1 NC_010473.1 hypothetical protein 2972706 ygcJ 6061588 ygcJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731653.1 2971615 R 316385 CDS YP_001731654.1 170082334 6061590 complement(2972719..2973201) 1 NC_010473.1 hypothetical protein 2973201 ygcK 6061590 ygcK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731654.1 2972719 R 316385 CDS YP_001731655.1 170082335 6061595 complement(2973194..2974702) 1 NC_010473.1 unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein 2974702 ygcL 6061595 ygcL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731655.1 2973194 R 316385 CDS YP_001731656.1 170082336 6061596 complement(2975117..2977783) 1 NC_010473.1 hypothetical protein 2977783 ygcB 6061596 ygcB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731656.1 2975117 R 316385 CDS YP_001731657.1 170082337 6061603 complement(2978142..2978876) 1 NC_010473.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 2978876 cysH 6061603 cysH Escherichia coli str. K-12 substr. DH10B phosphoadenosine phosphosulfate reductase YP_001731657.1 2978142 R 316385 CDS YP_001731658.1 170082338 6061617 complement(2980663..2982462) 1 NC_010473.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 2982462 cysJ 6061617 cysJ Escherichia coli str. K-12 substr. DH10B sulfite reductase subunit alpha YP_001731658.1 2980663 R 316385 CDS YP_001731659.1 170082339 6061625 2982778..2983143 1 NC_010473.1 6-pyruvoyl tetrahydrobiopterin synthase 2983143 sscR 6061625 sscR Escherichia coli str. K-12 substr. DH10B 6-pyruvoyl tetrahydrobiopterin synthase YP_001731659.1 2982778 D 316385 CDS YP_001731660.1 170082340 6061629 2983221..2984492 1 NC_010473.1 oxidoreductase 2984492 ygcN 6061629 ygcN Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001731660.1 2983221 D 316385 CDS YP_001731661.1 170082341 6061641 2984483..2984743 1 NC_010473.1 4Fe-4S binding protein 2984743 ygcO 6061641 ygcO Escherichia coli str. K-12 substr. DH10B 4Fe-4S binding protein YP_001731661.1 2984483 D 316385 CDS YP_001731662.1 170082342 6061644 2984760..2985335 1 NC_010473.1 anti-terminator regulatory protein 2985335 ygcP 6061644 ygcP Escherichia coli str. K-12 substr. DH10B anti-terminator regulatory protein YP_001731662.1 2984760 D 316385 CDS YP_001731663.1 170082343 6061648 complement(2985483..2986343) 1 NC_010473.1 flavoprotein 2986343 ygcQ 6061648 ygcQ Escherichia coli str. K-12 substr. DH10B flavoprotein YP_001731663.1 2985483 R 316385 CDS YP_001731664.1 170082344 6061652 complement(2986340..2987119) 1 NC_010473.1 flavoprotein 2987119 ygcR 6061652 ygcR Escherichia coli str. K-12 substr. DH10B flavoprotein YP_001731664.1 2986340 R 316385 CDS YP_001731665.1 170082345 6061654 complement(2987097..2988434) 1 NC_010473.1 transporter 2988434 ygcS 6061654 ygcS Escherichia coli str. K-12 substr. DH10B transporter YP_001731665.1 2987097 R 316385 CDS YP_001731666.1 170082346 6061662 complement(2988528..2989982) 1 NC_010473.1 FAD containing dehydrogenase 2989982 ygcU 6061662 ygcU Escherichia coli str. K-12 substr. DH10B FAD containing dehydrogenase YP_001731666.1 2988528 R 316385 CDS YP_001731667.1 170082347 6061686 complement(2990052..2990837) 1 NC_010473.1 deoxygluconate dehydrogenase 2990837 ygcW 6061686 ygcW Escherichia coli str. K-12 substr. DH10B deoxygluconate dehydrogenase YP_001731667.1 2990052 R 316385 CDS YP_001731668.1 170082348 6061691 2991156..2992433 1 NC_010473.1 transporter 2992433 yqcE 6061691 yqcE Escherichia coli str. K-12 substr. DH10B transporter YP_001731668.1 2991156 D 316385 CDS YP_001731669.1 170082349 6061697 2992460..2993938 1 NC_010473.1 kinase 2993938 ygcE 6061697 ygcE Escherichia coli str. K-12 substr. DH10B kinase YP_001731669.1 2992460 D 316385 CDS YP_001731670.1 170082350 6061701 complement(2995311..2995982) 1 NC_010473.1 hypothetical protein 2995982 ygcF 6061701 ygcF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731670.1 2995311 R 316385 CDS YP_001731671.1 170082351 6061727 complement(2997207..2998505) 1 NC_010473.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2998505 eno 6061727 eno Escherichia coli str. K-12 substr. DH10B phosphopyruvate hydratase YP_001731671.1 2997207 R 316385 CDS YP_001731672.1 170082352 6061747 complement(2998593..3000230) 1 NC_010473.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3000230 pyrG 6061747 pyrG Escherichia coli str. K-12 substr. DH10B CTP synthetase YP_001731672.1 2998593 R 316385 CDS YP_001731673.1 170082353 6061678 complement(3000458..3001249) 1 NC_010473.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3001249 mazG 6061678 mazG Escherichia coli str. K-12 substr. DH10B nucleoside triphosphate pyrophosphohydrolase YP_001731673.1 3000458 R 316385 CDS YP_001731674.1 170082354 6061751 complement(3001320..3001655) 1 NC_010473.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 3001655 chpA 6061751 chpA Escherichia coli str. K-12 substr. DH10B toxin ChpA YP_001731674.1 3001320 R 316385 CDS YP_001731675.1 170082355 6061752 complement(3001655..3001903) 1 NC_010473.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 3001903 chpR 6061752 chpR Escherichia coli str. K-12 substr. DH10B antitoxin MazE YP_001731675.1 3001655 R 316385 CDS YP_001731676.1 170082356 6058839 complement(3005599..3006900) 1 NC_010473.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3006900 rumA 6058839 rumA Escherichia coli str. K-12 substr. DH10B 23S rRNA 5-methyluridine methyltransferase YP_001731676.1 3005599 R 316385 CDS YP_001731677.1 170082357 6061766 3006957..3009713 1 NC_010473.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3009713 barA 6061766 barA Escherichia coli str. K-12 substr. DH10B hybrid sensory histidine kinase BarA YP_001731677.1 3006957 D 316385 CDS YP_001731678.1 170082358 6061767 complement(3009945..3011285) 1 NC_010473.1 (D)-glucarate dehydratase 1 3011285 gudD 6061767 gudD Escherichia coli str. K-12 substr. DH10B (D)-glucarate dehydratase 1 YP_001731678.1 3009945 R 316385 CDS YP_001731679.1 170082359 6061782 complement(3011306..3012646) 1 NC_010473.1 glucarate dehydratase 3012646 gudX 6061782 gudX Escherichia coli str. K-12 substr. DH10B glucarate dehydratase YP_001731679.1 3011306 R 316385 CDS YP_001731680.1 170082360 6061798 complement(3012648..3014000) 1 NC_010473.1 D-glucarate transporter 3014000 gudP 6061798 gudP Escherichia coli str. K-12 substr. DH10B D-glucarate transporter YP_001731680.1 3012648 R 316385 CDS YP_001731681.1 170082361 6061817 complement(3014435..3014884) 1 NC_010473.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3014884 yqcA 6061817 yqcA Escherichia coli str. K-12 substr. DH10B flavodoxin YP_001731681.1 3014435 R 316385 CDS YP_001731682.1 170082362 6061825 complement(3014902..3015684) 1 NC_010473.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3015684 truC 6061825 truC Escherichia coli str. K-12 substr. DH10B tRNA pseudouridine synthase C YP_001731682.1 3014902 R 316385 CDS YP_001731683.1 170082363 6061829 complement(3015684..3016013) 1 NC_010473.1 hypothetical protein 3016013 yqcC 6061829 yqcC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731683.1 3015684 R 316385 CDS YP_001731684.1 170082364 6061866 complement(3016635..3017180) 1 NC_010473.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 3017180 syd 6061866 syd Escherichia coli str. K-12 substr. DH10B SecY interacting protein Syd YP_001731684.1 3016635 R 316385 CDS YP_001731685.1 170082365 6061834 3017248..3018096 1 NC_010473.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3018096 queF 6061834 queF Escherichia coli str. K-12 substr. DH10B 7-cyano-7-deazaguanine reductase YP_001731685.1 3017248 D 316385 CDS YP_001731686.1 170082366 6061837 3018208..3019572 1 NC_010473.1 hypothetical protein 3019572 ygdH 6061837 ygdH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731686.1 3018208 D 316385 CDS YP_001731687.1 170082367 6061842 3020129..3021418 1 NC_010473.1 serine transporter 3021418 sdaC 6061842 sdaC Escherichia coli str. K-12 substr. DH10B serine transporter YP_001731687.1 3020129 D 316385 CDS YP_001731688.1 170082368 6061846 3021476..3022843 1 NC_010473.1 L-serine deaminase II 3022843 sdaB 6061846 sdaB Escherichia coli str. K-12 substr. DH10B L-serine deaminase II YP_001731688.1 3021476 D 316385 CDS YP_001731689.1 170082369 6061848 3022865..3023710 1 NC_010473.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3023710 xni 6061848 xni Escherichia coli str. K-12 substr. DH10B exonuclease IX YP_001731689.1 3022865 D 316385 CDS YP_001731690.1 170082370 6061852 complement(3023765..3024916) 1 NC_010473.1 L-1,2-propanediol oxidoreductase 3024916 fucO 6061852 fucO Escherichia coli str. K-12 substr. DH10B L-1,2-propanediol oxidoreductase YP_001731690.1 3023765 R 316385 CDS YP_001731691.1 170082371 6061867 complement(3024941..3025588) 1 NC_010473.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3025588 fucA 6061867 fucA Escherichia coli str. K-12 substr. DH10B L-fuculose phosphate aldolase YP_001731691.1 3024941 R 316385 CDS YP_001731692.1 170082372 6061878 3026135..3027451 1 NC_010473.1 L-fucose transporter 3027451 fucP 6061878 fucP Escherichia coli str. K-12 substr. DH10B L-fucose transporter YP_001731692.1 3026135 D 316385 CDS YP_001731693.1 170082373 6061885 3027484..3029259 1 NC_010473.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3029259 fucI 6061885 fucI Escherichia coli str. K-12 substr. DH10B L-fucose isomerase YP_001731693.1 3027484 D 316385 CDS YP_001731694.1 170082374 6061897 3029338..3030786 1 NC_010473.1 L-fuculokinase 3030786 fucK 6061897 fucK Escherichia coli str. K-12 substr. DH10B L-fuculokinase YP_001731694.1 3029338 D 316385 CDS YP_001731695.1 170082375 6061901 3030788..3031210 1 NC_010473.1 L-fucose mutarotase 3031210 fucU 6061901 fucU Escherichia coli str. K-12 substr. DH10B L-fucose mutarotase YP_001731695.1 3030788 D 316385 CDS YP_001731696.1 170082376 6061902 3031268..3031999 1 NC_010473.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3031999 fucR 6061902 fucR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator FucR YP_001731696.1 3031268 D 316385 CDS YP_001731697.1 170082377 6061903 complement(3032043..3033143) 1 NC_010473.1 putative RNA 2'-O-ribose methyltransferase 3033143 ygdE 6061903 ygdE Escherichia coli str. K-12 substr. DH10B putative RNA 2'-O-ribose methyltransferase YP_001731697.1 3032043 R 316385 CDS YP_001731698.1 170082378 6061904 complement(3033136..3033531) 1 NC_010473.1 hypothetical protein 3033531 ygdD 6061904 ygdD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731698.1 3033136 R 316385 CDS YP_001731699.1 170082379 6061909 complement(3033550..3034467) 1 NC_010473.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3034467 gcvA 6061909 gcvA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator GcvA YP_001731699.1 3033550 R 316385 CDS YP_001731700.1 170082380 6061656 complement(3034810..3035037) 1 NC_010473.1 hypothetical protein 3035037 ygdI 6061656 ygdI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731700.1 3034810 R 316385 CDS YP_001731701.1 170082381 6058699 3035229..3036434 1 NC_010473.1 cysteine sulfinate desulfinase 3036434 csdA 6058699 csdA Escherichia coli str. K-12 substr. DH10B cysteine sulfinate desulfinase YP_001731701.1 3035229 D 316385 CDS YP_001731702.1 170082382 6061920 3036434..3036877 1 NC_010473.1 Fe-S metabolism protein 3036877 ygdK 6061920 ygdK Escherichia coli str. K-12 substr. DH10B Fe-S metabolism protein YP_001731702.1 3036434 D 316385 CDS YP_001731703.1 170082383 6061925 complement(3036928..3037734) 1 NC_010473.1 hypothetical protein 3037734 ygdL 6061925 ygdL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731703.1 3036928 R 316385 CDS YP_001731704.1 170082384 6061927 complement(3037973..3039070) 1 NC_010473.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3039070 mltA 6061927 mltA Escherichia coli str. K-12 substr. DH10B murein transglycosylase A YP_001731704.1 3037973 R 316385 CDS YP_001731705.1 170082385 6061252 complement(3039649..3040902) 1 NC_010473.1 N-acetylmuramoyl-L-alanine amidase 3040902 amiC 6061252 amiC Escherichia coli str. K-12 substr. DH10B N-acetylmuramoyl-L-alanine amidase YP_001731705.1 3039649 R 316385 CDS YP_001731706.1 170082386 6061934 3041134..3042465 1 NC_010473.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3042465 argA 6061934 argA Escherichia coli str. K-12 substr. DH10B N-acetylglutamate synthase YP_001731706.1 3041134 D 316385 CDS YP_001731707.1 170082387 6061945 complement(3042527..3044353) 1 NC_010473.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3044353 recD 6061945 recD Escherichia coli str. K-12 substr. DH10B exonuclease V subunit alpha YP_001731707.1 3042527 R 316385 CDS YP_001731708.1 170082388 6061947 complement(3044353..3047895) 1 NC_010473.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3047895 recB 6061947 recB Escherichia coli str. K-12 substr. DH10B exonuclease V subunit beta YP_001731708.1 3044353 R 316385 CDS YP_001731709.1 170082389 6061953 complement(3047888..3050776) 1 NC_010473.1 protease III 3050776 ptrA 6061953 ptrA Escherichia coli str. K-12 substr. DH10B protease III YP_001731709.1 3047888 R 316385 CDS YP_001731710.1 170082390 6061960 complement(3050952..3054320) 1 NC_010473.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3054320 recC 6061960 recC Escherichia coli str. K-12 substr. DH10B exonuclease V subunit gamma YP_001731710.1 3050952 R 316385 CDS YP_001731711.1 170082391 6061963 complement(3054333..3054656) 1 NC_010473.1 hypothetical protein 3054656 ppdC 6061963 ppdC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731711.1 3054333 R 316385 CDS YP_001731712.1 170082392 6061970 complement(3054641..3055048) 1 NC_010473.1 hypothetical protein 3055048 ygdB 6061970 ygdB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731712.1 3054641 R 316385 CDS YP_001731713.1 170082393 6061972 complement(3055045..3055608) 1 NC_010473.1 hypothetical protein 3055608 ppdB 6061972 ppdB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731713.1 3055045 R 316385 CDS YP_001731714.1 170082394 6061975 complement(3055599..3056069) 1 NC_010473.1 hypothetical protein 3056069 ppdA 6061975 ppdA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731714.1 3055599 R 316385 CDS YP_001731715.1 170082395 6061980 complement(3056253..3057047) 1 NC_010473.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3057047 thyA 6061980 thyA Escherichia coli str. K-12 substr. DH10B thymidylate synthase YP_001731715.1 3056253 R 316385 CDS YP_001731716.1 170082396 6061986 complement(3057054..3057929) 1 NC_010473.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3057929 lgt 6061986 lgt Escherichia coli str. K-12 substr. DH10B prolipoprotein diacylglyceryl transferase YP_001731716.1 3057054 R 316385 CDS YP_001731717.1 170082397 6061987 complement(3058080..3060326) 1 NC_010473.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 3060326 ptsP 6061987 ptsP Escherichia coli str. K-12 substr. DH10B fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_001731717.1 3058080 R 316385 CDS YP_001731718.1 170082398 6061999 complement(3060339..3060869) 1 NC_010473.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3060869 nudH 6061999 nudH Escherichia coli str. K-12 substr. DH10B dinucleoside polyphosphate hydrolase YP_001731718.1 3060339 R 316385 CDS YP_001731719.1 170082399 6062009 3061554..3062243 1 NC_010473.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3062243 mutH 6062009 mutH Escherichia coli str. K-12 substr. DH10B DNA mismatch repair protein YP_001731719.1 3061554 D 316385 CDS YP_001731720.1 170082400 6062012 3062312..3063025 1 NC_010473.1 inner membrane protein 3063025 ygdQ 6062012 ygdQ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731720.1 3062312 D 316385 CDS YP_001731721.1 170082401 6062013 3063163..3063381 1 NC_010473.1 hypothetical protein 3063381 ygdR 6062013 ygdR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731721.1 3063163 D 316385 CDS YP_001731722.1 170082402 6062025 3063489..3064529 1 NC_010473.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase 3064529 tas 6062025 tas Escherichia coli str. K-12 substr. DH10B putative aldo-keto reductase YP_001731722.1 3063489 D 316385 CDS YP_001731723.1 170082403 6062030 complement(3064561..3065754) 1 NC_010473.1 lysophospholipid transporter LplT 3065754 ygeD 6062030 ygeD Escherichia coli str. K-12 substr. DH10B lysophospholipid transporter LplT YP_001731723.1 3064561 R 316385 CDS YP_001731724.1 170082404 6062031 complement(3065747..3067906) 1 NC_010473.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3067906 aas 6062031 aas Escherichia coli str. K-12 substr. DH10B bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_001731724.1 3065747 R 316385 CDS YP_001731725.1 170082405 6060784 3068491..3069522 1 NC_010473.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3069522 galR 6060784 galR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator GalR YP_001731725.1 3068491 D 316385 CDS YP_001731726.1 170082406 6062035 complement(3069529..3070791) 1 NC_010473.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3070791 lysA 6062035 lysA Escherichia coli str. K-12 substr. DH10B diaminopimelate decarboxylase YP_001731726.1 3069529 R 316385 CDS YP_001731727.1 170082407 6062036 3070913..3071848 1 NC_010473.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 3071848 lysR 6062036 lysR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator LysR YP_001731727.1 3070913 D 316385 CDS YP_001731728.1 170082408 6062037 complement(3071835..3072527) 1 NC_010473.1 putative racemase 3072527 ygeA 6062037 ygeA Escherichia coli str. K-12 substr. DH10B putative racemase YP_001731728.1 3071835 R 316385 CDS YP_001731729.1 170082409 6062041 complement(3072656..3074074) 1 NC_010473.1 arabinose transporter 3074074 araE 6062041 araE Escherichia coli str. K-12 substr. DH10B arabinose transporter YP_001731729.1 3072656 R 316385 CDS YP_001731730.1 170082410 6062044 complement(3074389..3075150) 1 NC_010473.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3075150 kduD 6062044 kduD Escherichia coli str. K-12 substr. DH10B 2-deoxy-D-gluconate 3-dehydrogenase YP_001731730.1 3074389 R 316385 CDS YP_001731731.1 170082411 6062046 complement(3075180..3076016) 1 NC_010473.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3076016 kduI 6062046 kduI Escherichia coli str. K-12 substr. DH10B 5-keto-4-deoxyuronate isomerase YP_001731731.1 3075180 R 316385 CDS YP_001731732.1 170082412 6062051 complement(3076303..3077484) 1 NC_010473.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3077484 yqeF 6062051 yqeF Escherichia coli str. K-12 substr. DH10B acetyl-CoA acetyltransferase YP_001731732.1 3076303 R 316385 CDS YP_001731733.1 170082413 6062053 3077739..3078968 1 NC_010473.1 transporter 3078968 yqeG 6062053 yqeG Escherichia coli str. K-12 substr. DH10B transporter YP_001731733.1 3077739 D 316385 CDS YP_001731734.1 170082414 6062054 3079428..3080060 1 NC_010473.1 hypothetical protein 3080060 yqeH 6062054 yqeH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731734.1 3079428 D 316385 CDS YP_001731735.1 170082415 6062059 3080394..3081203 1 NC_010473.1 transcriptional regulator 3081203 yqeI 6062059 yqeI Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001731735.1 3080394 D 316385 CDS YP_001731736.1 170082416 6062065 3081196..3081678 1 NC_010473.1 hypothetical protein 3081678 yqeJ 6062065 yqeJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731736.1 3081196 D 316385 CDS YP_001731737.1 170082417 6062069 complement(3081827..3082252) 1 NC_010473.1 hypothetical protein 3082252 yqeK 6062069 yqeK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731737.1 3081827 R 316385 CDS YP_001731738.1 170082418 6062071 3082446..3082892 1 NC_010473.1 hypothetical protein 3082892 ygeF 6062071 ygeF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731738.1 3082446 D 316385 CDS YP_001731739.1 170082419 6062074 3083160..3083651 1 NC_010473.1 chaperone 3083651 ygeG 6062074 ygeG Escherichia coli str. K-12 substr. DH10B chaperone YP_001731739.1 3083160 D 316385 CDS YP_001731740.1 170082420 6062081 3083986..3085362 1 NC_010473.1 transcriptional regulator 3085362 ygeH 6062081 ygeH Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001731740.1 3083986 D 316385 CDS YP_001731741.1 170082421 6061297 3085530..3085748 1 NC_010473.1 hypothetical protein 3085748 ygeI 6061297 ygeI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731741.1 3085530 D 316385 CDS YP_001731742.1 170082422 6059267 complement(3086352..3086795) 1 NC_010473.1 DNA-binding transcriptional regulator 3086795 ygeK 6059267 ygeK Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731742.1 3086352 R 316385 CDS YP_001731743.1 170082423 6062089 complement(3086829..3086984) 1 NC_010473.1 hypothetical protein 3086984 ygeL 6062089 ygeL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731743.1 3086829 R 316385 CDS YP_001731744.1 170082424 6062090 complement(3087206..3087637) 1 NC_010473.1 hypothetical protein 3087637 ygeM 6062090 ygeM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731744.1 3087206 R 316385 CDS YP_001731745.1 170082425 6062094 complement(3087854..3088279) 1 NC_010473.1 hypothetical protein 3088279 ygeO 6062094 ygeO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731745.1 3087854 R 316385 CDS YP_001731746.1 170082426 6062095 complement(3088264..3089169) 1 NC_010473.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3089169 insD-4 6062095 insD-4 Escherichia coli str. K-12 substr. DH10B insertion element IS2 transposase InsD YP_001731746.1 3088264 R 316385 CDS YP_001731747.1 170082427 6062097 complement(3089127..3089537) 1 NC_010473.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3089537 insC-4 6062097 insC-4 Escherichia coli str. K-12 substr. DH10B insertion sequence 2 OrfA protein YP_001731747.1 3089127 R 316385 CDS YP_001731748.1 170082428 6059742 complement(3091028..3091783) 1 NC_010473.1 TPR repeat-containing transcriptional regulator 3091783 ygeR 6059742 ygeR Escherichia coli str. K-12 substr. DH10B TPR repeat-containing transcriptional regulator YP_001731748.1 3091028 R 316385 CDS YP_001731749.1 170082429 6062105 3092237..3094495 1 NC_010473.1 putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3094495 xdhA 6062105 xdhA Escherichia coli str. K-12 substr. DH10B xanthine dehydrogenase subunit XdhA YP_001731749.1 3092237 D 316385 CDS YP_001731750.1 170082430 6062111 3094506..3095384 1 NC_010473.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3095384 xdhB 6062111 xdhB Escherichia coli str. K-12 substr. DH10B xanthine dehydrogenase subunit XdhB YP_001731750.1 3094506 D 316385 CDS YP_001731751.1 170082431 6062120 3095381..3095860 1 NC_010473.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3095860 xdhC 6062120 xdhC Escherichia coli str. K-12 substr. DH10B xanthine dehydrogenase subunit XdhC YP_001731751.1 3095381 D 316385 CDS YP_001731752.1 170082432 6062129 complement(3095900..3097678) 1 NC_010473.1 DNA-binding transcriptional regulator 3097678 ygeV 6062129 ygeV Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731752.1 3095900 R 316385 CDS YP_001731753.1 170082433 6062146 3098154..3099344 1 NC_010473.1 aspartate/ornithine carbamoyltransferase family protein 3099344 ygeW 6062146 ygeW Escherichia coli str. K-12 substr. DH10B aspartate/ornithine carbamoyltransferase family protein YP_001731753.1 3098154 D 316385 CDS YP_001731754.1 170082434 6062151 3099402..3100598 1 NC_010473.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3100598 ygeX 6062151 ygeX Escherichia coli str. K-12 substr. DH10B diaminopropionate ammonia-lyase YP_001731754.1 3099402 D 316385 CDS YP_001731755.1 170082435 6062159 3100656..3101867 1 NC_010473.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3101867 ygeY 6062159 ygeY Escherichia coli str. K-12 substr. DH10B peptidase YP_001731755.1 3100656 D 316385 CDS YP_001731756.1 170082436 6062165 3101920..3103305 1 NC_010473.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3103305 hyuA 6062165 hyuA Escherichia coli str. K-12 substr. DH10B phenylhydantoinase YP_001731756.1 3101920 D 316385 CDS YP_001731757.1 170082437 6062194 3103353..3104285 1 NC_010473.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3104285 yqeA 6062194 yqeA Escherichia coli str. K-12 substr. DH10B carbamate kinase YP_001731757.1 3103353 D 316385 CDS YP_001731758.1 170082438 6062205 complement(3104506..3106131) 1 NC_010473.1 hypothetical protein 3106131 yqeB 6062205 yqeB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731758.1 3104506 R 316385 CDS YP_001731759.1 170082439 6062215 complement(3106179..3106949) 1 NC_010473.1 hypothetical protein 3106949 yqeC 6062215 yqeC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731759.1 3106179 R 316385 CDS YP_001731760.1 170082440 6062219 3107052..3107630 1 NC_010473.1 hypothetical protein 3107630 ygfJ 6062219 ygfJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731760.1 3107052 D 316385 CDS YP_001731761.1 170082441 6062234 3107952..3111050 1 NC_010473.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 3111050 ygfK 6062234 ygfK Escherichia coli str. K-12 substr. DH10B putative selenate reductase subunit YgfK YP_001731761.1 3107952 D 316385 CDS YP_001731762.1 170082442 6062242 3111053..3112381 1 NC_010473.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 3112381 ssnA 6062242 ssnA Escherichia coli str. K-12 substr. DH10B putative chlorohydrolase/aminohydrolase YP_001731762.1 3111053 D 316385 CDS YP_001731763.1 170082443 6062244 3112432..3113211 1 NC_010473.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM 3113211 ygfM 6062244 ygfM Escherichia coli str. K-12 substr. DH10B putative selenate reductase subunit YgfM YP_001731763.1 3112432 D 316385 CDS YP_001731764.1 170082444 6062249 3113208..3116078 1 NC_010473.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN 3116078 xdhD 6062249 xdhD Escherichia coli str. K-12 substr. DH10B putative selenate reductase subunit YgfN YP_001731764.1 3113208 D 316385 CDS YP_001731765.1 170082445 6062259 3116243..3117643 1 NC_010473.1 transporter 3117643 ygfO 6062259 ygfO Escherichia coli str. K-12 substr. DH10B transporter YP_001731765.1 3116243 D 316385 CDS YP_001731766.1 170082446 6062266 3117658..3118977 1 NC_010473.1 Catalyzes the deamination of guanine; guanine deaminase 3118977 guaD 6062266 guaD Escherichia coli str. K-12 substr. DH10B guanine deaminase YP_001731766.1 3117658 D 316385 CDS YP_001731767.1 170082447 6062286 3119013..3120380 1 NC_010473.1 transporter 3120380 ygfQ 6062286 ygfQ Escherichia coli str. K-12 substr. DH10B transporter YP_001731767.1 3119013 D 316385 CDS YP_001731768.1 170082448 6062300 complement(3120904..3122823) 1 NC_010473.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 3122823 ygfT 6062300 ygfT Escherichia coli str. K-12 substr. DH10B putative oxidoreductase Fe-S binding subunit YP_001731768.1 3120904 R 316385 CDS YP_001731769.1 170082449 6062308 3123259..3124707 1 NC_010473.1 transporter 3124707 ygfU 6062308 ygfU Escherichia coli str. K-12 substr. DH10B transporter YP_001731769.1 3123259 D 316385 CDS YP_001731770.1 170082450 6062310 3124957..3125505 1 NC_010473.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3125505 idi 6062310 idi Escherichia coli str. K-12 substr. DH10B isopentenyl-diphosphate delta-isomerase YP_001731770.1 3124957 D 316385 CDS YP_001731771.1 170082451 6062324 complement(3125549..3127066) 1 NC_010473.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3127066 lysS 6062324 lysS Escherichia coli str. K-12 substr. DH10B lysyl-tRNA synthetase YP_001731771.1 3125549 R 316385 CDS YP_001731772.1 170082452 6062325 complement(join(3127076..3128098,3128100..3128174)) 1 NC_010473.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 3128174 prfB 6062325 prfB Escherichia coli str. K-12 substr. DH10B peptide chain release factor 2 YP_001731772.1 3127076 R 316385 CDS YP_001731773.1 170082453 6062327 complement(3128265..3129998) 1 NC_010473.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3129998 recJ 6062327 recJ Escherichia coli str. K-12 substr. DH10B ssDNA exonuclease RecJ YP_001731773.1 3128265 R 316385 CDS YP_001731774.1 170082454 6062354 complement(3130004..3130714) 1 NC_010473.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3130714 dsbC 6062354 dsbC Escherichia coli str. K-12 substr. DH10B thiol:disulfide interchange protein DsbC YP_001731774.1 3130004 R 316385 CDS YP_001731775.1 170082455 6062359 complement(3130739..3131635) 1 NC_010473.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3131635 xerD 6062359 xerD Escherichia coli str. K-12 substr. DH10B site-specific tyrosine recombinase XerD YP_001731775.1 3130739 R 316385 CDS YP_001731776.1 170082456 6062362 3131747..3132268 1 NC_010473.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3132268 fldB 6062362 fldB Escherichia coli str. K-12 substr. DH10B flavodoxin FldB YP_001731776.1 3131747 D 316385 CDS YP_001731777.1 170082457 6062367 complement(3132308..3132715) 1 NC_010473.1 hypothetical protein 3132715 ygfX 6062367 ygfX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731777.1 3132308 R 316385 CDS YP_001731778.1 170082458 6062393 complement(3132696..3132962) 1 NC_010473.1 hypothetical protein 3132962 ygfY 6062393 ygfY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731778.1 3132696 R 316385 CDS YP_001731779.1 170082459 6062395 3133205..3134185 1 NC_010473.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator 3134185 ygfZ 6062395 ygfZ Escherichia coli str. K-12 substr. DH10B putative global regulator YP_001731779.1 3133205 D 316385 CDS YP_001731780.1 170082460 6062396 complement(3134381..3135040) 1 NC_010473.1 oxidoreductase, inner membrane subunit 3135040 yqfA 6062396 yqfA Escherichia coli str. K-12 substr. DH10B oxidoreductase, inner membrane subunit YP_001731780.1 3134381 R 316385 CDS YP_001731781.1 170082461 6062398 complement(3135204..3135515) 1 NC_010473.1 hypothetical protein 3135515 yqfB 6062398 yqfB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731781.1 3135204 R 316385 CDS YP_001731782.1 170082462 6062426 3135554..3136993 1 NC_010473.1 6-phospho-beta-glucosidase 3136993 bglA 6062426 bglA Escherichia coli str. K-12 substr. DH10B 6-phospho-beta-glucosidase YP_001731782.1 3135554 D 316385 CDS YP_001731783.1 170082463 6062383 complement(3137050..3137793) 1 NC_010473.1 hypothetical protein 3137793 ygfF 6062383 ygfF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731783.1 3137050 R 316385 CDS YP_001731784.1 170082464 6059123 complement(3138060..3140933) 1 NC_010473.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3140933 gcvP 6059123 gcvP Escherichia coli str. K-12 substr. DH10B glycine dehydrogenase YP_001731784.1 3138060 R 316385 CDS YP_001731785.1 170082465 6059228 complement(3141052..3141441) 1 NC_010473.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3141441 gcvH 6059228 gcvH Escherichia coli str. K-12 substr. DH10B glycine cleavage system protein H YP_001731785.1 3141052 R 316385 CDS YP_001731786.1 170082466 6059093 complement(3143007..3144209) 1 NC_010473.1 hypothetical protein 3144209 visC 6059093 visC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731786.1 3143007 R 316385 CDS YP_001731787.1 170082467 6059242 complement(3144232..3145410) 1 NC_010473.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3145410 ubiH 6059242 ubiH Escherichia coli str. K-12 substr. DH10B 2-octaprenyl-6-methoxyphenyl hydroxylase YP_001731787.1 3144232 R 316385 CDS YP_001731788.1 170082468 6058726 complement(3145407..3146732) 1 NC_010473.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3146732 pepP 6058726 pepP Escherichia coli str. K-12 substr. DH10B proline aminopeptidase P II YP_001731788.1 3145407 R 316385 CDS YP_001731789.1 170082469 6062394 complement(3146758..3147336) 1 NC_010473.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3147336 ygfB 6062394 ygfB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731789.1 3146758 R 316385 CDS YP_001731790.1 170082470 6058955 3147504..3147833 1 NC_010473.1 protein that localizes to the cytokinetic ring; Z-ring-associated protein 3147833 zapA 6058955 zapA Escherichia coli str. K-12 substr. DH10B Z-ring-associated protein YP_001731790.1 3147504 D 316385 CDS YP_001731791.1 170082471 6058089 3148133..3148681 1 NC_010473.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase 3148681 ygfA 6058089 ygfA Escherichia coli str. K-12 substr. DH10B putative ligase YP_001731791.1 3148133 D 316385 CDS YP_001731792.1 170082472 6059149 complement(3149070..3150302) 1 NC_010473.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3150302 serA 6059149 serA Escherichia coli str. K-12 substr. DH10B D-3-phosphoglycerate dehydrogenase YP_001731792.1 3149070 R 316385 CDS YP_001731793.1 170082473 6060133 complement(3150558..3151217) 1 NC_010473.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3151217 rpiA 6060133 rpiA Escherichia coli str. K-12 substr. DH10B ribose-5-phosphate isomerase A YP_001731793.1 3150558 R 316385 CDS YP_001731794.1 170082474 6059646 complement(3151273..3151503) 1 NC_010473.1 hypothetical protein 3151503 yqfE 6059646 yqfE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731794.1 3151273 R 316385 CDS YP_001731795.1 170082475 6060214 3151645..3152538 1 NC_010473.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3152538 argP 6060214 argP Escherichia coli str. K-12 substr. DH10B chromosome replication initiation inhibitor protein YP_001731795.1 3151645 D 316385 CDS YP_001731796.1 170082476 6059230 3154879..3155874 1 NC_010473.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3155874 argK 6059230 argK Escherichia coli str. K-12 substr. DH10B arginine/ornithine transport system ATPase YP_001731796.1 3154879 D 316385 CDS YP_001731797.1 170082477 6058991 3155885..3156670 1 NC_010473.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3156670 ygfG 6058991 ygfG Escherichia coli str. K-12 substr. DH10B methylmalonyl-CoA decarboxylase YP_001731797.1 3155885 D 316385 CDS YP_001731798.1 170082478 6059051 complement(3158169..3159065) 1 NC_010473.1 DNA-binding transcriptional regulator 3159065 ygfI 6059051 ygfI Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731798.1 3158169 R 316385 CDS YP_001731799.1 170082479 6060433 complement(3159232..3159972) 1 NC_010473.1 hypothetical protein 3159972 yggE 6060433 yggE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731799.1 3159232 R 316385 CDS YP_001731800.1 170082480 6059222 complement(3160065..3160700) 1 NC_010473.1 Involved in the export of arginine; arginine exporter protein 3160700 argO 6059222 argO Escherichia coli str. K-12 substr. DH10B arginine exporter protein YP_001731800.1 3160065 R 316385 CDS YP_001731801.1 170082481 6058915 complement(3160839..3161699) 1 NC_010473.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3161699 mscS 6058915 mscS Escherichia coli str. K-12 substr. DH10B mechanosensitive channel MscS YP_001731801.1 3160839 R 316385 CDS YP_001731802.1 170082482 6059029 complement(3162057..3163136) 1 NC_010473.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3163136 fbaA 6059029 fbaA Escherichia coli str. K-12 substr. DH10B fructose-bisphosphate aldolase YP_001731802.1 3162057 R 316385 CDS YP_001731803.1 170082483 6062255 complement(3163351..3164514) 1 NC_010473.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3164514 pgk 6062255 pgk Escherichia coli str. K-12 substr. DH10B phosphoglycerate kinase YP_001731803.1 3163351 R 316385 CDS YP_001731804.1 170082484 6059857 complement(3164564..3165583) 1 NC_010473.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3165583 epd 6059857 epd Escherichia coli str. K-12 substr. DH10B erythrose 4-phosphate dehydrogenase YP_001731804.1 3164564 R 316385 CDS YP_001731805.1 170082485 6059854 complement(3165868..3166581) 1 NC_010473.1 putative fructose transport system kinase 3166581 frcK 6059854 frcK Escherichia coli str. K-12 substr. DH10B putative fructose transport system kinase YP_001731805.1 3165868 R 316385 CDS YP_001731806.1 170082486 6059855 complement(3166578..3167087) 1 NC_010473.1 putative DNA-binding transcriptional regulator 3167087 yggD 6059855 yggD Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001731806.1 3166578 R 316385 CDS YP_001731807.1 170082487 6059856 complement(3167109..3168074) 1 NC_010473.1 fructose-1,6-bisphosphatase II-like protein 3168074 yggF 6059856 yggF Escherichia coli str. K-12 substr. DH10B fructose-1,6-bisphosphatase II-like protein YP_001731807.1 3167109 R 316385 CDS YP_001731808.1 170082488 6062316 complement(3168071..3169348) 1 NC_010473.1 dehydrogenase 3169348 yggP 6062316 yggP Escherichia coli str. K-12 substr. DH10B dehydrogenase YP_001731808.1 3168071 R 316385 CDS YP_001731809.1 170082489 6059044 complement(3172735..3174726) 1 NC_010473.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3174726 tktA 6059044 tktA Escherichia coli str. K-12 substr. DH10B transketolase YP_001731809.1 3172735 R 316385 CDS YP_001731810.1 170082490 6062175 3175004..3175762 1 NC_010473.1 peptidase 3175762 yggG 6062175 yggG Escherichia coli str. K-12 substr. DH10B peptidase YP_001731810.1 3175004 D 316385 CDS YP_001731811.1 170082491 6062294 complement(3175968..3176888) 1 NC_010473.1 catalyzes the formation of putrescine from agmatine; agmatinase 3176888 speB 6062294 speB Escherichia coli str. K-12 substr. DH10B agmatinase YP_001731811.1 3175968 R 316385 CDS YP_001731812.1 170082492 6062390 complement(3177026..3179002) 1 NC_010473.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3179002 speA 6062390 speA Escherichia coli str. K-12 substr. DH10B arginine decarboxylase YP_001731812.1 3177026 R 316385 CDS YP_001731813.1 170082493 6059850 complement(3179011..3179157) 1 NC_010473.1 hypothetical protein 3179157 yqgB 6059850 yqgB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731813.1 3179011 R 316385 CDS YP_001731814.1 170082494 6059849 3179278..3179493 1 NC_010473.1 hypothetical protein 3179493 yqgC 6059849 yqgC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731814.1 3179278 D 316385 CDS YP_001731815.1 170082495 6059848 complement(3179490..3179741) 1 NC_010473.1 inner membrane protein 3179741 yqgD 6059848 yqgD Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731815.1 3179490 R 316385 CDS YP_001731816.1 170082496 6059845 3179797..3180951 1 NC_010473.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3180951 metK 6059845 metK Escherichia coli str. K-12 substr. DH10B S-adenosylmethionine synthetase YP_001731816.1 3179797 D 316385 CDS YP_001731817.1 170082497 6059846 3182846..3183343 1 NC_010473.1 hypothetical protein 3183343 sprT 6059846 sprT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731817.1 3182846 D 316385 CDS YP_001731818.1 170082498 6058108 3184225..3184956 1 NC_010473.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3184956 yggJ 6058108 yggJ Escherichia coli str. K-12 substr. DH10B 16S ribosomal RNA methyltransferase RsmE YP_001731818.1 3184225 D 316385 CDS YP_001731819.1 170082499 6059843 3184969..3185919 1 NC_010473.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3185919 gshB 6059843 gshB Escherichia coli str. K-12 substr. DH10B glutathione synthetase YP_001731819.1 3184969 D 316385 CDS YP_001731820.1 170082500 6059844 3186028..3186591 1 NC_010473.1 hypothetical protein 3186591 yqgE 6059844 yqgE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731820.1 3186028 D 316385 CDS YP_001731821.1 170082501 6059841 3186591..3187007 1 NC_010473.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3187007 yqgF 6059841 yqgF Escherichia coli str. K-12 substr. DH10B Holliday junction resolvase-like protein YP_001731821.1 3186591 D 316385 CDS YP_001731822.1 170082502 6059837 complement(3187191..3188171) 1 NC_010473.1 transporter 3188171 yggR 6059837 yggR Escherichia coli str. K-12 substr. DH10B transporter YP_001731822.1 3187191 R 316385 CDS YP_001731823.1 170082503 6059840 3188189..3188893 1 NC_010473.1 hypothetical protein 3188893 yggS 6059840 yggS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731823.1 3188189 D 316385 CDS YP_001731824.1 170082504 6058737 3188911..3189477 1 NC_010473.1 inner membrane protein 3189477 yggT 6058737 yggT Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731824.1 3188911 D 316385 CDS YP_001731825.1 170082505 6058805 3189474..3189764 1 NC_010473.1 hypothetical protein 3189764 yggU 6058805 yggU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731825.1 3189474 D 316385 CDS YP_001731826.1 170082506 6058814 3189772..3190365 1 NC_010473.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 3190365 yggV 6058814 yggV Escherichia coli str. K-12 substr. DH10B putative deoxyribonucleotide triphosphate pyrophosphatase YP_001731826.1 3189772 D 316385 CDS YP_001731827.1 170082507 6058883 3190358..3191494 1 NC_010473.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3191494 yggW 6058883 yggW Escherichia coli str. K-12 substr. DH10B coproporphyrinogen III oxidase YP_001731827.1 3190358 D 316385 CDS YP_001731828.1 170082508 6058960 complement(3191649..3192656) 1 NC_010473.1 hypothetical protein 3192656 yggM 6058960 yggM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731828.1 3191649 R 316385 CDS YP_001731829.1 170082509 6059065 complement(3192773..3193819) 1 NC_010473.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3193819 ansB 6059065 ansB Escherichia coli str. K-12 substr. DH10B L-asparaginase II YP_001731829.1 3192773 R 316385 CDS YP_001731830.1 170082510 6059124 complement(3193995..3194714) 1 NC_010473.1 hypothetical protein 3194714 yggN 6059124 yggN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731830.1 3193995 R 316385 CDS YP_001731831.1 170082511 6059203 complement(3194898..3195224) 1 NC_010473.1 hypothetical protein 3195224 yggL 6059203 yggL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731831.1 3194898 R 316385 CDS YP_001731832.1 170082512 6059235 complement(3195224..3195943) 1 NC_010473.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3195943 trmB 6059235 trmB Escherichia coli str. K-12 substr. DH10B tRNA (guanine-N(7)-)-methyltransferase YP_001731832.1 3195224 R 316385 CDS YP_001731833.1 170082513 6058798 3196104..3197156 1 NC_010473.1 adenine DNA glycosylase 3197156 mutY 6058798 mutY Escherichia coli str. K-12 substr. DH10B adenine DNA glycosylase YP_001731833.1 3196104 D 316385 CDS YP_001731834.1 170082514 6058989 3197184..3197459 1 NC_010473.1 protein that protects iron-sulfur proteins against oxidative damage; hypothetical protein 3197459 yggX 6058989 yggX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731834.1 3197184 D 316385 CDS YP_001731835.1 170082515 6059287 3197524..3198603 1 NC_010473.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3198603 mltC 6059287 mltC Escherichia coli str. K-12 substr. DH10B murein transglycosylase C YP_001731835.1 3197524 D 316385 CDS YP_001731836.1 170082516 6059714 3203945..3204754 1 NC_010473.1 bifunctional prepilin leader peptidase and methylase 3204754 pppA 6059714 pppA Escherichia coli str. K-12 substr. DH10B bifunctional prepilin leader peptidase and methylase YP_001731836.1 3203945 D 316385 CDS YP_001731837.1 170082517 6059717 3204820..3205230 1 NC_010473.1 hypothetical protein 3205230 yghG 6059717 yghG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731837.1 3204820 D 316385 CDS YP_001731838.1 170082518 6059998 3205377..3206243 1 NC_010473.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; putative type II secretion protein GspC 3206243 yghF 6059998 yghF Escherichia coli str. K-12 substr. DH10B putative type II secretion protein GspC YP_001731838.1 3205377 D 316385 CDS YP_001731839.1 170082519 6059317 3207171..3207707 1 NC_010473.1 putative general secretion pathway protein YghD 3207707 yghD 6059317 yghD Escherichia coli str. K-12 substr. DH10B putative general secretion pathway protein YghD YP_001731839.1 3207171 D 316385 CDS YP_001731840.1 170082520 6062348 complement(3208037..3208744) 1 NC_010473.1 inner membrane protein 3208744 yqgA 6062348 yqgA Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731840.1 3208037 R 316385 CDS YP_001731841.1 170082521 6059808 3209142..3211277 1 NC_010473.1 ornithine decarboxylase 3211277 speC 6059808 speC Escherichia coli str. K-12 substr. DH10B ornithine decarboxylase YP_001731841.1 3209142 D 316385 CDS YP_001731842.1 170082522 6060403 complement(3215364..3217046) 1 NC_010473.1 glycolate transporter 3217046 glcA 6060403 glcA Escherichia coli str. K-12 substr. DH10B glycolate transporter YP_001731842.1 3215364 R 316385 CDS YP_001731843.1 170082523 6059600 complement(3217401..3219572) 1 NC_010473.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3219572 glcB 6059600 glcB Escherichia coli str. K-12 substr. DH10B malate synthase G YP_001731843.1 3217401 R 316385 CDS YP_001731844.1 170082524 6059409 complement(3219594..3219998) 1 NC_010473.1 hypothetical protein 3219998 glcG 6059409 glcG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731844.1 3219594 R 316385 CDS YP_001731845.1 170082525 6059170 complement(3220003..3221226) 1 NC_010473.1 glycolate oxidase iron-sulfur subunit 3221226 glcF 6059170 glcF Escherichia coli str. K-12 substr. DH10B glycolate oxidase iron-sulfur subunit YP_001731845.1 3220003 R 316385 CDS YP_001731846.1 170082526 6058982 complement(3221237..3222289) 1 NC_010473.1 glycolate oxidase FAD binding subunit 3222289 glcE 6058982 glcE Escherichia coli str. K-12 substr. DH10B glycolate oxidase FAD binding subunit YP_001731846.1 3221237 R 316385 CDS YP_001731847.1 170082527 6058707 complement(3222289..3223788) 1 NC_010473.1 glycolate oxidase subunit GlcD 3223788 glcD 6058707 glcD Escherichia coli str. K-12 substr. DH10B glycolate oxidase subunit GlcD YP_001731847.1 3222289 R 316385 CDS YP_001731848.1 170082528 6058943 3224039..3224803 1 NC_010473.1 DNA-binding transcriptional regulator GlcC 3224803 glcC 6058943 glcC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator GlcC YP_001731848.1 3224039 D 316385 CDS YP_001731849.1 170082529 6058861 complement(3224810..3225982) 1 NC_010473.1 DNA-binding transcriptional regulator 3225982 yghO 6058861 yghO Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731849.1 3224810 R 316385 CDS YP_001731850.1 170082530 6059250 3225945..3226961 1 NC_010473.1 IS5 transposase and trans-activator 3226961 insH-9 6059250 insH-9 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001731850.1 3225945 D 316385 CDS YP_001731851.1 170082531 6059609 complement(3227108..3228175) 1 NC_010473.1 inner membrane protein 3228175 yghQ 6059609 yghQ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731851.1 3227108 R 316385 CDS YP_001731852.1 170082532 6059733 complement(3228221..3228979) 1 NC_010473.1 nucleoside triphosphate hydrolase domain-containing protein 3228979 yghR 6059733 yghR Escherichia coli str. K-12 substr. DH10B nucleoside triphosphate hydrolase domain-containing protein YP_001731852.1 3228221 R 316385 CDS YP_001731853.1 170082533 6060421 complement(3229011..3229724) 1 NC_010473.1 nucleoside triphosphate hydrolase domain-containing protein 3229724 yghS 6060421 yghS Escherichia coli str. K-12 substr. DH10B nucleoside triphosphate hydrolase domain-containing protein YP_001731853.1 3229011 R 316385 CDS YP_001731854.1 170082534 6060448 3229898..3230590 1 NC_010473.1 nucleoside triphosphate hydrolase domain-containing protein 3230590 yghT 6060448 yghT Escherichia coli str. K-12 substr. DH10B nucleoside triphosphate hydrolase domain-containing protein YP_001731854.1 3229898 D 316385 CDS YP_001731855.1 170082535 6059836 complement(3230639..3232138) 1 NC_010473.1 phosphate transporter 3232138 pitB 6059836 pitB Escherichia coli str. K-12 substr. DH10B phosphate transporter YP_001731855.1 3230639 R 316385 CDS YP_001731856.1 170082536 6058636 complement(3232430..3234289) 1 NC_010473.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3234289 gss 6058636 gss Escherichia coli str. K-12 substr. DH10B bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_001731856.1 3232430 R 316385 CDS YP_001731857.1 170082537 6060407 3234494..3235360 1 NC_010473.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 3235360 yghU 6060407 yghU Escherichia coli str. K-12 substr. DH10B putative glutathione S-transferase YghU YP_001731857.1 3234494 D 316385 CDS YP_001731858.1 170082538 6060185 complement(3235483..3235731) 1 NC_010473.1 hydrogenase 2 accessory protein HypG 3235731 hybG 6060185 hybG Escherichia coli str. K-12 substr. DH10B hydrogenase 2 accessory protein HypG YP_001731858.1 3235483 R 316385 CDS YP_001731859.1 170082539 6059933 complement(3235744..3236085) 1 NC_010473.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3236085 hybF 6059933 hybF Escherichia coli str. K-12 substr. DH10B hydrogenase nickel incorporation protein HybF YP_001731859.1 3235744 R 316385 CDS YP_001731860.1 170082540 6059763 complement(3236078..3236566) 1 NC_010473.1 hydrogenase 2-specific chaperone 3236566 hybE 6059763 hybE Escherichia coli str. K-12 substr. DH10B hydrogenase 2-specific chaperone YP_001731860.1 3236078 R 316385 CDS YP_001731861.1 170082541 6059053 complement(3236559..3237053) 1 NC_010473.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3237053 hybD 6059053 hybD Escherichia coli str. K-12 substr. DH10B hydrogenase 2 maturation endopeptidase YP_001731861.1 3236559 R 316385 CDS YP_001731862.1 170082542 6059621 complement(3237053..3238756) 1 NC_010473.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3238756 hybC 6059621 hybC Escherichia coli str. K-12 substr. DH10B hydrogenase 2 large subunit YP_001731862.1 3237053 R 316385 CDS YP_001731863.1 170082543 6059651 complement(3238753..3239931) 1 NC_010473.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit 3239931 hybB 6059651 hybB Escherichia coli str. K-12 substr. DH10B putative hydrogenase 2 b cytochrome subunit YP_001731863.1 3238753 R 316385 CDS YP_001731864.1 170082544 6060220 complement(3239921..3240907) 1 NC_010473.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3240907 hybA 6060220 hybA Escherichia coli str. K-12 substr. DH10B hydrogenase 2 protein HybA YP_001731864.1 3239921 R 316385 CDS YP_001731865.1 170082545 6059486 complement(3240910..3242028) 1 NC_010473.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3242028 hybO 6059486 hybO Escherichia coli str. K-12 substr. DH10B hydrogenase 2 small subunit YP_001731865.1 3240910 R 316385 CDS YP_001731866.1 170082546 6060830 complement(3242217..3242504) 1 NC_010473.1 hypothetical protein 3242504 yghW 6060830 yghW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731866.1 3242217 R 316385 CDS YP_001731867.1 170082547 6060886 3243664..3244704 1 NC_010473.1 aldo-keto reductase 3244704 yghZ 6060886 yghZ Escherichia coli str. K-12 substr. DH10B aldo-keto reductase YP_001731867.1 3243664 D 316385 CDS YP_001731868.1 170082548 6061166 complement(3244744..3245238) 1 NC_010473.1 hypothetical protein 3245238 yqhA 6061166 yqhA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731868.1 3244744 R 316385 CDS YP_001731869.1 170082549 6060437 3245429..3246313 1 NC_010473.1 oxidoreductase 3246313 yghA 6060437 yghA Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001731869.1 3245429 D 316385 CDS YP_001731870.1 170082550 6062154 complement(3246585..3247010) 1 NC_010473.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3247010 exbD 6062154 exbD Escherichia coli str. K-12 substr. DH10B biopolymer transport protein ExbD YP_001731870.1 3246585 R 316385 CDS YP_001731871.1 170082551 6060124 complement(3247017..3247751) 1 NC_010473.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3247751 exbB 6060124 exbB Escherichia coli str. K-12 substr. DH10B biopolymer transport protein ExbB YP_001731871.1 3247017 R 316385 CDS YP_001731872.1 170082552 6060368 3248003..3249190 1 NC_010473.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3249190 metC 6060368 metC Escherichia coli str. K-12 substr. DH10B cystathionine beta-lyase YP_001731872.1 3248003 D 316385 CDS YP_001731873.1 170082553 6060297 3249330..3249989 1 NC_010473.1 inner membrane protein 3249989 yghB 6060297 yghB Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731873.1 3249330 D 316385 CDS YP_001731874.1 170082554 6060268 complement(3250029..3250985) 1 NC_010473.1 DNA-binding transcriptional regulator 3250985 yqhC 6060268 yqhC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731874.1 3250029 R 316385 CDS YP_001731875.1 170082555 6060229 3251122..3252285 1 NC_010473.1 alcohol dehydrogenase 3252285 yqhD 6060229 yqhD Escherichia coli str. K-12 substr. DH10B alcohol dehydrogenase YP_001731875.1 3251122 D 316385 CDS YP_001731876.1 170082556 6060228 3252390..3253217 1 NC_010473.1 methylglyoxal reductase/-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3253217 dkgA 6060228 dkgA Escherichia coli str. K-12 substr. DH10B 2,5-diketo-D-gluconate reductase A YP_001731876.1 3252390 D 316385 CDS YP_001731877.1 170082557 6060156 3253417..3254343 1 NC_010473.1 hypothetical protein 3254343 yqhG 6060156 yqhG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731877.1 3253417 D 316385 CDS YP_001731878.1 170082558 6059972 3254394..3254651 1 NC_010473.1 putative outer membrane lipoprotein 3254651 yqhH 6059972 yqhH Escherichia coli str. K-12 substr. DH10B putative outer membrane lipoprotein YP_001731878.1 3254394 D 316385 CDS YP_001731879.1 170082559 6059932 complement(3254694..3256913) 1 NC_010473.1 hypothetical protein 3256913 ygiQ 6059932 ygiQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731879.1 3254694 R 316385 CDS YP_001731880.1 170082560 6059776 complement(3257024..3258436) 1 NC_010473.1 repressor protein for FtsI 3258436 sufI 6059776 sufI Escherichia coli str. K-12 substr. DH10B repressor protein for FtsI YP_001731880.1 3257024 R 316385 CDS YP_001731881.1 170082561 6059749 complement(3258511..3259248) 1 NC_010473.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 3259248 plsC 6059749 plsC Escherichia coli str. K-12 substr. DH10B 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001731881.1 3258511 R 316385 CDS YP_001731882.1 170082562 6059861 complement(3259482..3261740) 1 NC_010473.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3261740 parC 6059861 parC Escherichia coli str. K-12 substr. DH10B DNA topoisomerase IV subunit A YP_001731882.1 3259482 R 316385 CDS YP_001731883.1 170082563 6059434 complement(3261878..3263485) 1 NC_010473.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein 3263485 ygiS 6059434 ygiS Escherichia coli str. K-12 substr. DH10B putative binding protein YP_001731883.1 3261878 R 316385 CDS YP_001731884.1 170082564 6059627 complement(3263618..3264013) 1 NC_010473.1 DNA-binding transcriptional regulator 3264013 ygiT 6059627 ygiT Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731884.1 3263618 R 316385 CDS YP_001731885.1 170082565 6059579 complement(3264015..3264311) 1 NC_010473.1 quorum-sensing regulator 3264311 mqsR 6059579 mqsR Escherichia coli str. K-12 substr. DH10B quorum-sensing regulator YP_001731885.1 3264015 R 316385 CDS YP_001731886.1 170082566 6059388 complement(3264516..3264998) 1 NC_010473.1 transcriptional regulator 3264998 ygiV 6059388 ygiV Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001731886.1 3264516 R 316385 CDS YP_001731887.1 170082567 6059466 complement(3265051..3265443) 1 NC_010473.1 hypothetical protein 3265443 ygiW 6059466 ygiW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731887.1 3265051 R 316385 CDS YP_001731888.1 170082568 6059403 3265595..3266254 1 NC_010473.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3266254 qseB 6059403 qseB Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator QseB YP_001731888.1 3265595 D 316385 CDS YP_001731889.1 170082569 6061989 3266251..3267600 1 NC_010473.1 sensor protein QseC 3267600 qseC 6061989 qseC Escherichia coli str. K-12 substr. DH10B sensor protein QseC YP_001731889.1 3266251 D 316385 CDS YP_001731890.1 170082570 6058998 complement(3267646..3267978) 1 NC_010473.1 inner membrane protein 3267978 ygiZ 6058998 ygiZ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731890.1 3267646 R 316385 CDS YP_001731891.1 170082571 6059365 3268297..3268878 1 NC_010473.1 NADPH quinone reductase 3268878 mdaB 6059365 mdaB Escherichia coli str. K-12 substr. DH10B NADPH quinone reductase YP_001731891.1 3268297 D 316385 CDS YP_001731892.1 170082572 6058853 3268909..3269223 1 NC_010473.1 quinol monooxygenase 3269223 ygiN 6058853 ygiN Escherichia coli str. K-12 substr. DH10B quinol monooxygenase YP_001731892.1 3268909 D 316385 CDS YP_001731893.1 170082573 6059314 complement(3269271..3271163) 1 NC_010473.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3271163 parE 6059314 parE Escherichia coli str. K-12 substr. DH10B DNA topoisomerase IV subunit B YP_001731893.1 3269271 R 316385 CDS YP_001731894.1 170082574 6059272 complement(3271192..3271773) 1 NC_010473.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 3271773 yqiA 6059272 yqiA Escherichia coli str. K-12 substr. DH10B esterase YqiA YP_001731894.1 3271192 R 316385 CDS YP_001731895.1 170082575 6059315 complement(3271773..3272600) 1 NC_010473.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 3272600 cpdA 6059315 cpdA Escherichia coli str. K-12 substr. DH10B cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_001731895.1 3271773 R 316385 CDS YP_001731896.1 170082576 6059243 complement(3272625..3273047) 1 NC_010473.1 hypothetical protein 3273047 yqiB 6059243 yqiB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731896.1 3272625 R 316385 CDS YP_001731897.1 170082577 6060275 complement(3273048..3273677) 1 NC_010473.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 3273677 nudF 6060275 nudF Escherichia coli str. K-12 substr. DH10B ADP-ribose pyrophosphatase NudF YP_001731897.1 3273048 R 316385 CDS YP_001731898.1 170082578 6059239 3273882..3275363 1 NC_010473.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3275363 tolC 6059239 tolC Escherichia coli str. K-12 substr. DH10B outer membrane channel protein YP_001731898.1 3273882 D 316385 CDS YP_001731899.1 170082579 6061704 3275363..3275623 1 NC_010473.1 hypothetical protein 3275623 ygiA 6061704 ygiA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731899.1 3275363 D 316385 CDS YP_001731900.1 170082580 6059186 3275607..3276182 1 NC_010473.1 hypothetical protein 3276182 ygiB 6059186 ygiB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731900.1 3275607 D 316385 CDS YP_001731901.1 170082581 6059117 3276188..3277348 1 NC_010473.1 hypothetical protein 3277348 ygiC 6059117 ygiC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731901.1 3276188 D 316385 CDS YP_001731902.1 170082582 6062019 complement(3277386..3278174) 1 NC_010473.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3278174 ygiD 6062019 ygiD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731902.1 3277386 R 316385 CDS YP_001731903.1 170082583 6059071 3278317..3279090 1 NC_010473.1 zinc transporter ZupT 3279090 zupT 6059071 zupT Escherichia coli str. K-12 substr. DH10B zinc transporter ZupT YP_001731903.1 3278317 D 316385 CDS YP_001731904.1 170082584 6060998 complement(3279580..3280233) 1 NC_010473.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3280233 ribB 6060998 ribB Escherichia coli str. K-12 substr. DH10B 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001731904.1 3279580 R 316385 CDS YP_001731905.1 170082585 6058904 3280607..3280897 1 NC_010473.1 hypothetical protein 3280897 yqiC 6058904 yqiC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731905.1 3280607 D 316385 CDS YP_001731906.1 170082586 6058857 3281181..3281732 1 NC_010473.1 putative fimbrial protein 3281732 ygiL 6058857 ygiL Escherichia coli str. K-12 substr. DH10B putative fimbrial protein YP_001731906.1 3281181 D 316385 CDS YP_001731907.1 170082587 6058808 3281909..3282319 1 NC_010473.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3282319 insC-5 6058808 insC-5 Escherichia coli str. K-12 substr. DH10B insertion sequence 2 OrfA protein YP_001731907.1 3281909 D 316385 CDS YP_001731908.1 170082588 6058804 3282277..3283182 1 NC_010473.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3283182 insD-5 6058804 insD-5 Escherichia coli str. K-12 substr. DH10B insertion element IS2 transposase InsD YP_001731908.1 3282277 D 316385 CDS YP_001731909.1 170082589 6058778 3283167..3285632 1 NC_010473.1 outer membrane usher protein 3285632 yqiG 6058778 yqiG Escherichia coli str. K-12 substr. DH10B outer membrane usher protein YP_001731909.1 3283167 D 316385 CDS YP_001731910.1 170082590 6058753 3285648..3286397 1 NC_010473.1 periplasmic pilin chaperone 3286397 yqiH 6058753 yqiH Escherichia coli str. K-12 substr. DH10B periplasmic pilin chaperone YP_001731910.1 3285648 D 316385 CDS YP_001731911.1 170082591 6058721 3286399..3287463 1 NC_010473.1 hypothetical protein 3287463 yqiI 6058721 yqiI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731911.1 3286399 D 316385 CDS YP_001731912.1 170082592 6060867 complement(3287506..3287706) 1 NC_010473.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3287706 glgS 6060867 glgS Escherichia coli str. K-12 substr. DH10B glycogen synthesis protein GlgS YP_001731912.1 3287506 R 316385 CDS YP_001731913.1 170082593 6058712 3287975..3288604 1 NC_010473.1 inner membrane protein 3288604 yqiJ 6058712 yqiJ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731913.1 3287975 D 316385 CDS YP_001731914.1 170082594 6058718 3288631..3290292 1 NC_010473.1 hypothetical protein 3290292 yqiK 6058718 yqiK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731914.1 3288631 D 316385 CDS YP_001731915.1 170082595 6058470 complement(3291087..3292520) 1 NC_010473.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3292520 rfaE 6058470 rfaE Escherichia coli str. K-12 substr. DH10B bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_001731915.1 3291087 R 316385 CDS YP_001731916.1 170082596 6059104 complement(3292568..3295408) 1 NC_010473.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3295408 glnE 6059104 glnE Escherichia coli str. K-12 substr. DH10B bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_001731916.1 3292568 R 316385 CDS YP_001731917.1 170082597 6061930 complement(3295431..3296732) 1 NC_010473.1 adenylate cyclase 3296732 ygiF 6061930 ygiF Escherichia coli str. K-12 substr. DH10B adenylate cyclase YP_001731917.1 3295431 R 316385 CDS YP_001731918.1 170082598 6059648 3296974..3297594 1 NC_010473.1 putative signal transduction protein 3297594 htrG 6059648 htrG Escherichia coli str. K-12 substr. DH10B putative signal transduction protein YP_001731918.1 3296974 D 316385 CDS YP_001731919.1 170082599 6059369 3297658..3298896 1 NC_010473.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3298896 cca 6059369 cca Escherichia coli str. K-12 substr. DH10B multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_001731919.1 3297658 D 316385 CDS YP_001731920.1 170082600 6060188 complement(3299077..3299898) 1 NC_010473.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3299898 bacA 6060188 bacA Escherichia coli str. K-12 substr. DH10B undecaprenyl pyrophosphate phosphatase YP_001731920.1 3299077 R 316385 CDS YP_001731921.1 170082601 6059227 complement(3299988..3300356) 1 NC_010473.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3300356 folB 6059227 folB Escherichia coli str. K-12 substr. DH10B bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_001731921.1 3299988 R 316385 CDS YP_001731922.1 170082602 6062076 3300461..3301078 1 NC_010473.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 3301078 ygiH 6062076 ygiH Escherichia coli str. K-12 substr. DH10B putative glycerol-3-phosphate acyltransferase PlsY YP_001731922.1 3300461 D 316385 CDS YP_001731923.1 170082603 6060919 complement(3301091..3302023) 1 NC_010473.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3302023 ygiP 6060919 ygiP Escherichia coli str. K-12 substr. DH10B transcriptional activator TtdR YP_001731923.1 3301091 R 316385 CDS YP_001731924.1 170082604 6061071 3302230..3303141 1 NC_010473.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3303141 ttdA 6061071 ttdA Escherichia coli str. K-12 substr. DH10B tartrate dehydratase subunit alpha YP_001731924.1 3302230 D 316385 CDS YP_001731925.1 170082605 6062007 3303138..3303743 1 NC_010473.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3303743 ttdB 6062007 ttdB Escherichia coli str. K-12 substr. DH10B L(+)-tartrate dehydratase subunit beta YP_001731925.1 3303138 D 316385 CDS YP_001731926.1 170082606 6060896 3303791..3305254 1 NC_010473.1 tartrate:succinate antiporter 3305254 ygjE 6060896 ygjE Escherichia coli str. K-12 substr. DH10B tartrate:succinate antiporter YP_001731926.1 3303791 D 316385 CDS YP_001731927.1 170082607 6060505 complement(3305297..3306310) 1 NC_010473.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 3306310 ygjD 6060505 ygjD Escherichia coli str. K-12 substr. DH10B putative DNA-binding/iron metalloprotein/AP endonuclease YP_001731927.1 3305297 R 316385 CDS YP_001731928.1 170082608 6060790 3306548..3306763 1 NC_010473.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3306763 rpsU 6060790 rpsU Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S21 YP_001731928.1 3306548 D 316385 CDS YP_001731929.1 170082609 6058823 3306874..3308619 1 NC_010473.1 synthesizes RNA primers at the replication forks; DNA primase 3308619 dnaG 6058823 dnaG Escherichia coli str. K-12 substr. DH10B DNA primase YP_001731929.1 3306874 D 316385 CDS YP_001731930.1 170082610 6062000 3308814..3310655 1 NC_010473.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3310655 rpoD 6062000 rpoD Escherichia coli str. K-12 substr. DH10B RNA polymerase sigma factor RpoD YP_001731930.1 3308814 D 316385 CDS YP_001731931.1 170082611 6058812 complement(3310734..3311240) 1 NC_010473.1 G/U mismatch-specific DNA glycosylase 3311240 mug 6058812 mug Escherichia coli str. K-12 substr. DH10B G/U mismatch-specific DNA glycosylase YP_001731931.1 3310734 R 316385 CDS YP_001731932.1 170082612 6059513 complement(3311494..3312258) 1 NC_010473.1 siderophore interacting protein 3312258 yqjH 6059513 yqjH Escherichia coli str. K-12 substr. DH10B siderophore interacting protein YP_001731932.1 3311494 R 316385 CDS YP_001731933.1 170082613 6061322 3312546..3313169 1 NC_010473.1 transcriptional regulator 3313169 yqjI 6061322 yqjI Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001731933.1 3312546 D 316385 CDS YP_001731934.1 170082614 6060341 complement(3313323..3314843) 1 NC_010473.1 fused signal transducer for aerotaxis sensory component; methyl accepting chemotaxis component 3314843 aer 6060341 aer Escherichia coli str. K-12 substr. DH10B fused signal transducer for aerotaxis sensory component; methyl accepting chemotaxis component YP_001731934.1 3313323 R 316385 CDS YP_001731935.1 170082615 6061580 3315234..3316640 1 NC_010473.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3316640 ygjG 6061580 ygjG Escherichia coli str. K-12 substr. DH10B putrescine--2-oxoglutarate aminotransferase YP_001731935.1 3315234 D 316385 CDS YP_001731936.1 170082616 6062406 complement(3316682..3317014) 1 NC_010473.1 hypothetical protein 3317014 ygjH 6062406 ygjH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731936.1 3316682 R 316385 CDS YP_001731937.1 170082617 6060803 3317233..3318216 1 NC_010473.1 DNA-binding transcriptional repressor EbgR 3318216 ebgR 6060803 ebgR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor EbgR YP_001731937.1 3317233 D 316385 CDS YP_001731938.1 170082618 6061880 3318400..3321492 1 NC_010473.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3321492 ebgA 6061880 ebgA Escherichia coli str. K-12 substr. DH10B cryptic beta-D-galactosidase subunit alpha YP_001731938.1 3318400 D 316385 CDS YP_001731939.1 170082619 6061882 3321489..3321938 1 NC_010473.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3321938 ebgC 6061882 ebgC Escherichia coli str. K-12 substr. DH10B cryptic beta-D-galactosidase subunit beta YP_001731939.1 3321489 D 316385 CDS YP_001731940.1 170082620 6061838 3322001..3323434 1 NC_010473.1 transporter 3323434 ygjI 6061838 ygjI Escherichia coli str. K-12 substr. DH10B transporter YP_001731940.1 3322001 D 316385 CDS YP_001731941.1 170082621 6060920 3323568..3324638 1 NC_010473.1 hypothetical protein 3324638 ygjJ 6060920 ygjJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731941.1 3323568 D 316385 CDS YP_001731942.1 170082622 6061770 3324655..3327006 1 NC_010473.1 putative glycosyl hydrolase 3327006 ygjK 6061770 ygjK Escherichia coli str. K-12 substr. DH10B putative glycosyl hydrolase YP_001731942.1 3324655 D 316385 CDS YP_001731943.1 170082623 6058764 3327432..3329450 1 NC_010473.1 2,4-dienoyl-CoA reductase 3329450 fadH 6058764 fadH Escherichia coli str. K-12 substr. DH10B 2,4-dienoyl-CoA reductase YP_001731943.1 3327432 D 316385 CDS YP_001731944.1 170082624 6061936 complement(3329495..3329911) 1 NC_010473.1 DNA-binding transcriptional regulator 3329911 ygjM 6061936 ygjM Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731944.1 3329495 R 316385 CDS YP_001731945.1 170082625 6060917 complement(3329908..3330222) 1 NC_010473.1 hypothetical protein 3330222 ygjN 6060917 ygjN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731945.1 3329908 R 316385 CDS YP_001731946.1 170082626 6060967 complement(3330506..3331642) 1 NC_010473.1 methyltransferase small subunit 3331642 ygjO 6060967 ygjO Escherichia coli str. K-12 substr. DH10B methyltransferase small subunit YP_001731946.1 3330506 R 316385 CDS YP_001731947.1 170082627 6060517 3331727..3332230 1 NC_010473.1 metal dependent hydrolase 3332230 ygjP 6060517 ygjP Escherichia coli str. K-12 substr. DH10B metal dependent hydrolase YP_001731947.1 3331727 D 316385 CDS YP_001731948.1 170082628 6060984 3332307..3332999 1 NC_010473.1 thioredoxin-like protein 3332999 ygjQ 6060984 ygjQ Escherichia coli str. K-12 substr. DH10B thioredoxin-like protein YP_001731948.1 3332307 D 316385 CDS YP_001731949.1 170082629 6060994 3333060..3334064 1 NC_010473.1 NAD(P)-binding dehydrogenase 3334064 ygjR 6060994 ygjR Escherichia coli str. K-12 substr. DH10B NAD(P)-binding dehydrogenase YP_001731949.1 3333060 D 316385 CDS YP_001731950.1 170082630 6059283 3334347..3335312 1 NC_010473.1 inner membrane protein, part of terminus 3335312 alx 6059283 alx Escherichia coli str. K-12 substr. DH10B inner membrane protein, part of terminus YP_001731950.1 3334347 D 316385 CDS YP_001731951.1 170082631 6062011 3335711..3336955 1 NC_010473.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3336955 sstT 6062011 sstT Escherichia coli str. K-12 substr. DH10B serine/threonine transporter SstT YP_001731951.1 3335711 D 316385 CDS YP_001731952.1 170082632 6060980 complement(3336960..3337511) 1 NC_010473.1 inner membrane protein 3337511 ygjV 6060980 ygjV Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731952.1 3336960 R 316385 CDS YP_001731953.1 170082633 6061004 complement(3337594..3339081) 1 NC_010473.1 altronate hydrolase 3339081 uxaA 6061004 uxaA Escherichia coli str. K-12 substr. DH10B altronate hydrolase YP_001731953.1 3337594 R 316385 CDS YP_001731954.1 170082634 6062050 complement(3339096..3340508) 1 NC_010473.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3340508 uxaC 6062050 uxaC Escherichia coli str. K-12 substr. DH10B glucuronate isomerase YP_001731954.1 3339096 R 316385 CDS YP_001731955.1 170082635 6061067 3340871..3342289 1 NC_010473.1 hexuronate transporter 3342289 exuT 6061067 exuT Escherichia coli str. K-12 substr. DH10B hexuronate transporter YP_001731955.1 3340871 D 316385 CDS YP_001731956.1 170082636 6061073 3342419..3343195 1 NC_010473.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3343195 exuR 6061073 exuR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor ExuR YP_001731956.1 3342419 D 316385 CDS YP_001731957.1 170082637 6060664 3343540..3344202 1 NC_010473.1 inner membrane protein 3344202 yqjA 6060664 yqjA Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731957.1 3343540 D 316385 CDS YP_001731958.1 170082638 6062109 3344206..3344589 1 NC_010473.1 hypothetical protein 3344589 yqjB 6062109 yqjB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731958.1 3344206 D 316385 CDS YP_001731959.1 170082639 6060516 3344736..3345104 1 NC_010473.1 hypothetical protein 3345104 yqjC 6060516 yqjC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731959.1 3344736 D 316385 CDS YP_001731960.1 170082640 6060510 3345142..3345447 1 NC_010473.1 hypothetical protein 3345447 yqjD 6060510 yqjD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731960.1 3345142 D 316385 CDS YP_001731961.1 170082641 6060601 3345450..3345854 1 NC_010473.1 inner membrane protein 3345854 yqjE 6060601 yqjE Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731961.1 3345450 D 316385 CDS YP_001731962.1 170082642 6060031 3345844..3346143 1 NC_010473.1 hypothetical protein 3346143 yqjK 6060031 yqjK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731962.1 3345844 D 316385 CDS YP_001731963.1 170082643 6060671 3346329..3346721 1 NC_010473.1 quinol oxidase subunit 3346721 yqjF 6060671 yqjF Escherichia coli str. K-12 substr. DH10B quinol oxidase subunit YP_001731963.1 3346329 D 316385 CDS YP_001731964.1 170082644 6060600 3346791..3347777 1 NC_010473.1 S-transferase 3347777 yqjG 6060600 yqjG Escherichia coli str. K-12 substr. DH10B S-transferase YP_001731964.1 3346791 D 316385 CDS YP_001731965.1 170082645 6060690 3348071..3348436 1 NC_010473.1 inner membrane protein 3348436 yhaH 6060690 yhaH Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731965.1 3348071 D 316385 CDS YP_001731966.1 170082646 6060807 3348678..3349034 1 NC_010473.1 inner membrane protein 3349034 yhaI 6060807 yhaI Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001731966.1 3348678 D 316385 CDS YP_001731967.1 170082647 6060739 complement(3349085..3349981) 1 NC_010473.1 DNA-binding transcriptional regulator 3349981 yhaJ 6060739 yhaJ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001731967.1 3349085 R 316385 CDS YP_001731968.1 170082648 6060874 3350086..3350787 1 NC_010473.1 pirin-related protein 3350787 yhaK 6060874 yhaK Escherichia coli str. K-12 substr. DH10B pirin-related protein YP_001731968.1 3350086 D 316385 CDS YP_001731969.1 170082649 6060882 3350810..3350974 1 NC_010473.1 hypothetical protein 3350974 yhaL 6060882 yhaL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731969.1 3350810 D 316385 CDS YP_001731970.1 170082650 6060895 complement(3351108..3352418) 1 NC_010473.1 hypothetical protein 3352418 yhaM 6060895 yhaM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731970.1 3351108 R 316385 CDS YP_001731971.1 170082651 6061061 complement(3352446..3353714) 1 NC_010473.1 transporter 3353714 yhaO 6061061 yhaO Escherichia coli str. K-12 substr. DH10B transporter YP_001731971.1 3352446 R 316385 CDS YP_001731972.1 170082652 6061115 complement(3354052..3355416) 1 NC_010473.1 L-serine dehydratase 3 3355416 tdcG 6061115 tdcG Escherichia coli str. K-12 substr. DH10B L-serine dehydratase 3 YP_001731972.1 3354052 R 316385 CDS YP_001731973.1 170082653 6061037 complement(3355488..3355877) 1 NC_010473.1 hypothetical protein 3355877 tdcF 6061037 tdcF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731973.1 3355488 R 316385 CDS YP_001731974.1 170082654 6061236 complement(3355891..3358185) 1 NC_010473.1 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase 3358185 tdcE 6061236 tdcE Escherichia coli str. K-12 substr. DH10B pyruvate formate-lyase 4/2-ketobutyrate formate-lyase YP_001731974.1 3355891 R 316385 CDS YP_001731975.1 170082655 6059823 complement(3358219..3359439) 1 NC_010473.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 3359439 tdcD 6059823 tdcD Escherichia coli str. K-12 substr. DH10B propionate/acetate kinase YP_001731975.1 3358219 R 316385 CDS YP_001731976.1 170082656 6061826 complement(3359453..3360784) 1 NC_010473.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3360784 tdcC 6061826 tdcC Escherichia coli str. K-12 substr. DH10B threonine/serine transporter TdcC YP_001731976.1 3359453 R 316385 CDS YP_001731977.1 170082657 6061793 complement(3360806..3361795) 1 NC_010473.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3361795 tdcB 6061793 tdcB Escherichia coli str. K-12 substr. DH10B threonine dehydratase YP_001731977.1 3360806 R 316385 CDS YP_001731978.1 170082658 6061941 complement(3361894..3362832) 1 NC_010473.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3362832 tdcA 6061941 tdcA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator TdcA YP_001731978.1 3361894 R 316385 CDS YP_001731979.1 170082659 6061957 3363147..3363365 1 NC_010473.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3363365 tdcR 6061957 tdcR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator TdcR YP_001731979.1 3363147 D 316385 CDS YP_001731980.1 170082660 6061921 3363621..3364160 1 NC_010473.1 hypothetical protein 3364160 yhaB 6061921 yhaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731980.1 3363621 D 316385 CDS YP_001731981.1 170082661 6062122 3364182..3365369 1 NC_010473.1 hypothetical protein 3365369 yhaC 6062122 yhaC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731981.1 3364182 D 316385 CDS YP_001731982.1 170082662 6059015 complement(3366392..3367618) 1 NC_010473.1 glycerate kinase 3367618 garK 6059015 garK Escherichia coli str. K-12 substr. DH10B glycerate kinase YP_001731982.1 3366392 R 316385 CDS YP_001731983.1 170082663 6062429 complement(3367634..3368524) 1 NC_010473.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3368524 garR 6062429 garR Escherichia coli str. K-12 substr. DH10B tartronate semialdehyde reductase YP_001731983.1 3367634 R 316385 CDS YP_001731984.1 170082664 6058659 complement(3368554..3369324) 1 NC_010473.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3369324 garL 6058659 garL Escherichia coli str. K-12 substr. DH10B alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_001731984.1 3368554 R 316385 CDS YP_001731985.1 170082665 6059838 complement(3369340..3370674) 1 NC_010473.1 (D)-galactarate transporter 3370674 garP 6059838 garP Escherichia coli str. K-12 substr. DH10B (D)-galactarate transporter YP_001731985.1 3369340 R 316385 CDS YP_001731986.1 170082666 6058623 3371049..3372620 1 NC_010473.1 (D)-galactarate dehydrogenase 3372620 garD 6058623 garD Escherichia coli str. K-12 substr. DH10B (D)-galactarate dehydrogenase YP_001731986.1 3371049 D 316385 CDS YP_001731987.1 170082667 6060414 3372769..3373104 1 NC_010473.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 3373104 sohA 6060414 sohA Escherichia coli str. K-12 substr. DH10B putative regulator PrlF YP_001731987.1 3372769 D 316385 CDS YP_001731988.1 170082668 6059918 3373104..3373568 1 NC_010473.1 hypothetical protein 3373568 yhaV 6059918 yhaV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731988.1 3373104 D 316385 CDS YP_001731989.1 170082669 6060218 complement(3373623..3374432) 1 NC_010473.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 3374432 agaR 6060218 agaR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator AgaR YP_001731989.1 3373623 R 316385 CDS YP_001731990.1 170082670 6059873 3374681..3375961 1 NC_010473.1 tagatose 6-phosphate aldolase 1, kbaZ subunit 3375961 kbaZ 6059873 kbaZ Escherichia coli str. K-12 substr. DH10B tagatose 6-phosphate aldolase 1, kbaZ subunit YP_001731990.1 3374681 D 316385 CDS YP_001731991.1 170082671 6059676 3375984..3376457 1 NC_010473.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3376457 agaV 6059676 agaV Escherichia coli str. K-12 substr. DH10B PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_001731991.1 3375984 D 316385 CDS YP_001731992.1 170082672 6059370 3376889..3377392 1 NC_010473.1 hypothetical protein 3377392 agaA 6059370 agaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001731992.1 3376889 D 316385 CDS YP_001731993.1 170082673 6059618 3377743..3378897 1 NC_010473.1 tagatose-6-phosphate ketose/aldose isomerase 3378897 agaS 6059618 agaS Escherichia coli str. K-12 substr. DH10B tagatose-6-phosphate ketose/aldose isomerase YP_001731993.1 3377743 D 316385 CDS YP_001731994.1 170082674 6060404 3378910..3379770 1 NC_010473.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3379770 kbaY 6060404 kbaY Escherichia coli str. K-12 substr. DH10B tagatose-bisphosphate aldolase YP_001731994.1 3378910 D 316385 CDS YP_001731995.1 170082675 6059465 3379937..3380413 1 NC_010473.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3380413 agaB 6059465 agaB Escherichia coli str. K-12 substr. DH10B PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_001731995.1 3379937 D 316385 CDS YP_001731996.1 170082676 6060456 3380452..3381255 1 NC_010473.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3381255 agaC 6060456 agaC Escherichia coli str. K-12 substr. DH10B PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_001731996.1 3380452 D 316385 CDS YP_001731997.1 170082677 6058770 3381245..3382036 1 NC_010473.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3382036 agaD 6058770 agaD Escherichia coli str. K-12 substr. DH10B PTS system N-acetylgalactosamine-specific transporter subunit IID YP_001731997.1 3381245 D 316385 CDS YP_001731998.1 170082678 6058676 3382037..3382792 1 NC_010473.1 galactosamine-6-phosphate isomerase 3382792 agaI 6058676 agaI Escherichia coli str. K-12 substr. DH10B galactosamine-6-phosphate isomerase YP_001731998.1 3382037 D 316385 CDS YP_001731999.1 170082679 6060611 3383193..3383777 1 NC_010473.1 fimbrial-like adhesin protein 3383777 yraH 6060611 yraH Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001731999.1 3383193 D 316385 CDS YP_001732000.1 170082680 6058743 3383857..3384552 1 NC_010473.1 periplasmic pilin chaperone 3384552 yraI 6058743 yraI Escherichia coli str. K-12 substr. DH10B periplasmic pilin chaperone YP_001732000.1 3383857 D 316385 CDS YP_001732001.1 170082681 6060029 3384581..3387097 1 NC_010473.1 outer membrane protein 3387097 yraJ 6060029 yraJ Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001732001.1 3384581 D 316385 CDS YP_001732002.1 170082682 6061016 3387108..3388199 1 NC_010473.1 fimbrial-like adhesin protein 3388199 yraK 6061016 yraK Escherichia coli str. K-12 substr. DH10B fimbrial-like adhesin protein YP_001732002.1 3387108 D 316385 CDS YP_001732003.1 170082683 6060933 complement(3388242..3389102) 1 NC_010473.1 methyltransferase 3389102 yraL 6060933 yraL Escherichia coli str. K-12 substr. DH10B methyltransferase YP_001732003.1 3388242 R 316385 CDS YP_001732004.1 170082684 6058795 3389167..3391203 1 NC_010473.1 hypothetical protein 3391203 yraM 6058795 yraM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732004.1 3389167 D 316385 CDS YP_001732005.1 170082685 6061281 3391161..3391556 1 NC_010473.1 hypothetical protein 3391556 yraN 6061281 yraN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732005.1 3391161 D 316385 CDS YP_001732006.1 170082686 6061155 3391576..3392166 1 NC_010473.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3392166 diaA 6061155 diaA Escherichia coli str. K-12 substr. DH10B DnaA initiator-associating protein DiaA YP_001732006.1 3391576 D 316385 CDS YP_001732007.1 170082687 6061462 3392176..3392751 1 NC_010473.1 hypothetical protein 3392751 yraP 6061462 yraP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732007.1 3392176 D 316385 CDS YP_001732008.1 170082688 6061600 complement(3392865..3393905) 1 NC_010473.1 permease 3393905 yraQ 6061600 yraQ Escherichia coli str. K-12 substr. DH10B permease YP_001732008.1 3392865 R 316385 CDS YP_001732009.1 170082689 6059180 complement(3393978..3394613) 1 NC_010473.1 nucleoside-diphosphate-sugar epimerase 3394613 yraR 6059180 yraR Escherichia coli str. K-12 substr. DH10B nucleoside-diphosphate-sugar epimerase YP_001732009.1 3393978 R 316385 CDS YP_001732010.1 170082690 6061855 3394741..3395259 1 NC_010473.1 intracellular protease 3395259 yhbO 6061855 yhbO Escherichia coli str. K-12 substr. DH10B intracellular protease YP_001732010.1 3394741 D 316385 CDS YP_001732011.1 170082691 6061907 complement(3395239..3395682) 1 NC_010473.1 hypothetical protein 3395682 yhbP 6061907 yhbP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732011.1 3395239 R 316385 CDS YP_001732012.1 170082692 6062073 3395733..3396035 1 NC_010473.1 GIY-YIG nuclease superfamily protein 3396035 yhbQ 6062073 yhbQ Escherichia coli str. K-12 substr. DH10B GIY-YIG nuclease superfamily protein YP_001732012.1 3395733 D 316385 CDS YP_001732013.1 170082693 6061969 complement(3396022..3396525) 1 NC_010473.1 acyltransferase 3396525 yhbS 6061969 yhbS Escherichia coli str. K-12 substr. DH10B acyltransferase YP_001732013.1 3396022 R 316385 CDS YP_001732014.1 170082694 6062210 complement(3396519..3397043) 1 NC_010473.1 lipid carrier protein 3397043 yhbT 6062210 yhbT Escherichia coli str. K-12 substr. DH10B lipid carrier protein YP_001732014.1 3396519 R 316385 CDS YP_001732015.1 170082695 6060299 3397252..3398247 1 NC_010473.1 peptidase (collagenase-like) 3398247 yhbU 6060299 yhbU Escherichia coli str. K-12 substr. DH10B peptidase (collagenase-like) YP_001732015.1 3397252 D 316385 CDS YP_001732016.1 170082696 6060466 3398256..3399134 1 NC_010473.1 protease 3399134 yhbV 6060466 yhbV Escherichia coli str. K-12 substr. DH10B protease YP_001732016.1 3398256 D 316385 CDS YP_001732017.1 170082697 6060441 3399215..3400222 1 NC_010473.1 hypothetical protein 3400222 yhbW 6060441 yhbW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732017.1 3399215 D 316385 CDS YP_001732018.1 170082698 6060128 complement(3400340..3401584) 1 NC_010473.1 tryptophan transporter of high affinity; tryptophan permease 3401584 mtr 6060128 mtr Escherichia coli str. K-12 substr. DH10B tryptophan permease YP_001732018.1 3400340 R 316385 CDS YP_001732019.1 170082699 6060420 complement(3401738..3403627) 1 NC_010473.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3403627 deaD 6060420 deaD Escherichia coli str. K-12 substr. DH10B ATP-dependent RNA helicase DeaD YP_001732019.1 3401738 R 316385 CDS YP_001732020.1 170082700 6060373 complement(3403807..3404691) 1 NC_010473.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3404691 nlpI 6060373 nlpI Escherichia coli str. K-12 substr. DH10B lipoprotein NlpI YP_001732020.1 3403807 R 316385 CDS YP_001732021.1 170082701 6060347 complement(3404800..3407004) 1 NC_010473.1 polynucleotide phosphorylase/polyadenylase 3407004 pnp 6060347 pnp Escherichia coli str. K-12 substr. DH10B polynucleotide phosphorylase/polyadenylase YP_001732021.1 3404800 R 316385 CDS YP_001732022.1 170082702 6062290 complement(3407182..3407451) 1 NC_010473.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3407451 rpsO 6062290 rpsO Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S15 YP_001732022.1 3407182 R 316385 CDS YP_001732023.1 170082703 6060312 complement(3407600..3408544) 1 NC_010473.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3408544 truB 6060312 truB Escherichia coli str. K-12 substr. DH10B tRNA pseudouridine synthase B YP_001732023.1 3407600 R 316385 CDS YP_001732024.1 170082704 6060256 complement(3408544..3408945) 1 NC_010473.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3408945 rbfA 6060256 rbfA Escherichia coli str. K-12 substr. DH10B ribosome-binding factor A YP_001732024.1 3408544 R 316385 CDS YP_001732025.1 170082705 6060060 complement(3409109..3411781) 1 NC_010473.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3411781 infB 6060060 infB Escherichia coli str. K-12 substr. DH10B translation initiation factor IF-2 YP_001732025.1 3409109 R 316385 CDS YP_001732026.1 170082706 6060254 complement(3411806..3413293) 1 NC_010473.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3413293 nusA 6060254 nusA Escherichia coli str. K-12 substr. DH10B transcription elongation factor NusA YP_001732026.1 3411806 R 316385 CDS YP_001732027.1 170082707 6060226 complement(3413321..3413773) 1 NC_010473.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3413773 yhbC 6060226 yhbC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732027.1 3413321 R 316385 CDS YP_001732028.1 170082708 6060897 3414404..3415747 1 NC_010473.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3415747 argG 6060897 argG Escherichia coli str. K-12 substr. DH10B argininosuccinate synthase YP_001732028.1 3414404 D 316385 CDS YP_001732029.1 170082709 6060010 complement(3415755..3417380) 1 NC_010473.1 hydrolase, inner membrane 3417380 yhbX 6060010 yhbX Escherichia coli str. K-12 substr. DH10B hydrolase, inner membrane YP_001732029.1 3415755 R 316385 CDS YP_001732030.1 170082710 6059703 complement(3417940..3418272) 1 NC_010473.1 preprotein translocase subunit SecG 3418272 secG 6059703 secG Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit SecG YP_001732030.1 3417940 R 316385 CDS YP_001732031.1 170082711 6059875 complement(3418500..3419837) 1 NC_010473.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3419837 glmM 6059875 glmM Escherichia coli str. K-12 substr. DH10B phosphoglucosamine mutase YP_001732031.1 3418500 R 316385 CDS YP_001732032.1 170082712 6058533 complement(3419830..3420678) 1 NC_010473.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3420678 folP 6058533 folP Escherichia coli str. K-12 substr. DH10B dihydropteroate synthase YP_001732032.1 3419830 R 316385 CDS YP_001732033.1 170082713 6059910 complement(3420768..3422702) 1 NC_010473.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3422702 hflB 6059910 hflB Escherichia coli str. K-12 substr. DH10B ATP-dependent metalloprotease YP_001732033.1 3420768 R 316385 CDS YP_001732034.1 170082714 6059785 complement(3422802..3423431) 1 NC_010473.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 3423431 rrmJ 6059785 rrmJ Escherichia coli str. K-12 substr. DH10B 23S rRNA methyltransferase J YP_001732034.1 3422802 R 316385 CDS YP_001732035.1 170082715 6059772 3423557..3423850 1 NC_010473.1 RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3423850 yhbY 6059772 yhbY Escherichia coli str. K-12 substr. DH10B RNA-binding protein YhbY YP_001732035.1 3423557 D 316385 CDS YP_001732036.1 170082716 6058137 complement(3424006..3424482) 1 NC_010473.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3424482 greA 6058137 greA Escherichia coli str. K-12 substr. DH10B transcription elongation factor GreA YP_001732036.1 3424006 R 316385 CDS YP_001732037.1 170082717 6058226 3424730..3426163 1 NC_010473.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3426163 dacB 6058226 dacB Escherichia coli str. K-12 substr. DH10B D-alanyl-D-alanine carboxypeptidase YP_001732037.1 3424730 D 316385 CDS YP_001732038.1 170082718 6059698 complement(3426349..3427521) 1 NC_010473.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3427521 obgE 6059698 obgE Escherichia coli str. K-12 substr. DH10B GTPase ObgE YP_001732038.1 3426349 R 316385 CDS YP_001732039.1 170082719 6059731 complement(3427537..3428502) 1 NC_010473.1 inner membrane protein 3428502 yhbE 6059731 yhbE Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732039.1 3427537 R 316385 CDS YP_001732040.1 170082720 6061239 complement(3428629..3428886) 1 NC_010473.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3428886 rpmA 6061239 rpmA Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L27 YP_001732040.1 3428629 R 316385 CDS YP_001732041.1 170082721 6061349 complement(3428907..3429218) 1 NC_010473.1 50S ribosomal protein L21 3429218 rplU 6061349 rplU Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L21 YP_001732041.1 3428907 R 316385 CDS YP_001732042.1 170082722 6061444 3429477..3430448 1 NC_010473.1 octaprenyl diphosphate synthase 3430448 ispB 6061444 ispB Escherichia coli str. K-12 substr. DH10B octaprenyl diphosphate synthase YP_001732042.1 3429477 D 316385 CDS YP_001732043.1 170082723 6061616 3430676..3430954 1 NC_010473.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3430954 sfsB 6061616 sfsB Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator Nlp YP_001732043.1 3430676 D 316385 CDS YP_001732044.1 170082724 6061591 complement(3432316..3432570) 1 NC_010473.1 DNA-binding transcriptional regulator 3432570 yrbA 6061591 yrbA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732044.1 3432316 R 316385 CDS YP_001732045.1 170082725 6061664 complement(3432730..3433023) 1 NC_010473.1 hypothetical protein 3433023 yrbB 6061664 yrbB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732045.1 3432730 R 316385 CDS YP_001732046.1 170082726 6061722 complement(3433023..3433658) 1 NC_010473.1 organic solvent ABC transporter 3433658 yrbC 6061722 yrbC Escherichia coli str. K-12 substr. DH10B organic solvent ABC transporter YP_001732046.1 3433023 R 316385 CDS YP_001732047.1 170082727 6059771 complement(3433677..3434228) 1 NC_010473.1 organic solvent ABC transporter 3434228 yrbD 6059771 yrbD Escherichia coli str. K-12 substr. DH10B organic solvent ABC transporter YP_001732047.1 3433677 R 316385 CDS YP_001732048.1 170082728 6059723 complement(3434233..3435015) 1 NC_010473.1 toluene ABC transporter membrane protein 3435015 yrbE 6059723 yrbE Escherichia coli str. K-12 substr. DH10B toluene ABC transporter membrane protein YP_001732048.1 3434233 R 316385 CDS YP_001732049.1 170082729 6059696 complement(3435023..3435832) 1 NC_010473.1 ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF 3435832 yrbF 6059696 yrbF Escherichia coli str. K-12 substr. DH10B putative ABC transporter ATP-binding protein YrbF YP_001732049.1 3435023 R 316385 CDS YP_001732050.1 170082730 6059629 3436042..3437019 1 NC_010473.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 3437019 yrbG 6059629 yrbG Escherichia coli str. K-12 substr. DH10B putative calcium/sodium:proton antiporter YP_001732050.1 3436042 D 316385 CDS YP_001732051.1 170082731 6059640 3437033..3438019 1 NC_010473.1 D-arabinose 5-phosphate isomerase 3438019 kdsD 6059640 kdsD Escherichia coli str. K-12 substr. DH10B D-arabinose 5-phosphate isomerase YP_001732051.1 3437033 D 316385 CDS YP_001732052.1 170082732 6059643 3438040..3438606 1 NC_010473.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3438606 kdsC 6059643 kdsC Escherichia coli str. K-12 substr. DH10B 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_001732052.1 3438040 D 316385 CDS YP_001732053.1 170082733 6062226 3438603..3439178 1 NC_010473.1 hypothetical protein 3439178 yrbK 6062226 yrbK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732053.1 3438603 D 316385 CDS YP_001732054.1 170082734 6062126 3439147..3439704 1 NC_010473.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3439704 yhbN 6062126 yhbN Escherichia coli str. K-12 substr. DH10B lipopolysaccharide transport periplasmic protein LptA YP_001732054.1 3439147 D 316385 CDS YP_001732055.1 170082735 6062361 3439711..3440436 1 NC_010473.1 putative ABC transporter ATP-binding protein YhbG 3440436 yhbG 6062361 yhbG Escherichia coli str. K-12 substr. DH10B putative ABC transporter ATP-binding protein YhbG YP_001732055.1 3439711 D 316385 CDS YP_001732056.1 170082736 6059391 3440484..3441917 1 NC_010473.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3441917 rpoN 6059391 rpoN Escherichia coli str. K-12 substr. DH10B RNA polymerase factor sigma-54 YP_001732056.1 3440484 D 316385 CDS YP_001732057.1 170082737 6059493 3441940..3442227 1 NC_010473.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 3442227 hpf 6059493 hpf Escherichia coli str. K-12 substr. DH10B putative sigma(54) modulation protein YP_001732057.1 3441940 D 316385 CDS YP_001732058.1 170082738 6059412 3442345..3442836 1 NC_010473.1 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3442836 ptsN 6059412 ptsN Escherichia coli str. K-12 substr. DH10B PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_001732058.1 3442345 D 316385 CDS YP_001732059.1 170082739 6059601 3442882..3443736 1 NC_010473.1 hypothetical protein 3443736 yhbJ 6059601 yhbJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732059.1 3442882 D 316385 CDS YP_001732060.1 170082740 6059308 3443733..3444005 1 NC_010473.1 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3444005 npr 6059308 npr Escherichia coli str. K-12 substr. DH10B phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_001732060.1 3443733 D 316385 CDS YP_001732061.1 170082741 6062005 3444219..3444851 1 NC_010473.1 hypothetical protein 3444851 yrbL 6062005 yrbL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732061.1 3444219 D 316385 CDS YP_001732062.1 170082742 6059432 complement(3444848..3445576) 1 NC_010473.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3445576 mtgA 6059432 mtgA Escherichia coli str. K-12 substr. DH10B monofunctional biosynthetic peptidoglycan transglycosylase YP_001732062.1 3444848 R 316385 CDS YP_001732063.1 170082743 6059389 complement(3445573..3446226) 1 NC_010473.1 isoprenoid biosynthesis protein with amidotransferase-like domain 3446226 elbB 6059389 elbB Escherichia coli str. K-12 substr. DH10B isoprenoid biosynthesis protein with amidotransferase-like domain YP_001732063.1 3445573 R 316385 CDS YP_001732064.1 170082744 6058702 complement(3446456..3448792) 1 NC_010473.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3448792 arcB 6058702 arcB Escherichia coli str. K-12 substr. DH10B aerobic respiration control sensor protein ArcB YP_001732064.1 3446456 R 316385 CDS YP_001732065.1 170082745 6059397 complement(3448888..3449817) 1 NC_010473.1 Fe-S oxidoreductase 3449817 yhcC 6059397 yhcC Escherichia coli str. K-12 substr. DH10B Fe-S oxidoreductase YP_001732065.1 3448888 R 316385 CDS YP_001732066.1 170082746 6059473 3450399..3454952 1 NC_010473.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3454952 gltB 6059473 gltB Escherichia coli str. K-12 substr. DH10B glutamate synthase subunit alpha YP_001732066.1 3450399 D 316385 CDS YP_001732067.1 170082747 6059526 3454965..3456383 1 NC_010473.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3456383 gltD 6059526 gltD Escherichia coli str. K-12 substr. DH10B glutamate synthase subunit beta YP_001732067.1 3454965 D 316385 CDS YP_001732068.1 170082748 6061745 3456943..3457707 1 NC_010473.1 hypothetical protein 3457707 gltF 6061745 gltF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732068.1 3456943 D 316385 CDS YP_001732069.1 170082749 6059353 3457879..3458553 1 NC_010473.1 member of the periplasmic pilus chaperone family of proteins; putative periplasmic chaperone protein 3458553 yhcA 6059353 yhcA Escherichia coli str. K-12 substr. DH10B putative periplasmic chaperone protein YP_001732069.1 3457879 D 316385 CDS YP_001732070.1 170082750 6059310 3458574..3460955 1 NC_010473.1 outer membrane protein 3460955 yhcD 6059310 yhcD Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001732070.1 3458574 D 316385 CDS YP_001732071.1 170082751 6061910 complement(3461469..3462485) 1 NC_010473.1 IS5 transposase and trans-activator 3462485 insH-10 6061910 insH-10 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001732071.1 3461469 R 316385 CDS YP_001732072.1 170082752 6059335 3462693..3463409 1 NC_010473.1 transcriptional regulator 3463409 yhcF 6059335 yhcF Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001732072.1 3462693 D 316385 CDS YP_001732073.1 170082753 6062410 complement(3464781..3465245) 1 NC_010473.1 hypothetical protein 3465245 yhcH 6062410 yhcH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732073.1 3464781 R 316385 CDS YP_001732074.1 170082754 6059328 complement(3465242..3466117) 1 NC_010473.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3466117 nanK 6059328 nanK Escherichia coli str. K-12 substr. DH10B N-acetylmannosamine kinase YP_001732074.1 3465242 R 316385 CDS YP_001732075.1 170082755 6059330 complement(3466114..3466803) 1 NC_010473.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3466803 nanE 6059330 nanE Escherichia coli str. K-12 substr. DH10B N-acetylmannosamine-6-phosphate 2-epimerase YP_001732075.1 3466114 R 316385 CDS YP_001732076.1 170082756 6058549 complement(3466851..3468341) 1 NC_010473.1 putative sialic acid transporter 3468341 nanT 6058549 nanT Escherichia coli str. K-12 substr. DH10B putative sialic acid transporter YP_001732076.1 3466851 R 316385 CDS YP_001732077.1 170082757 6061738 complement(3468450..3469343) 1 NC_010473.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3469343 nanA 6061738 nanA Escherichia coli str. K-12 substr. DH10B N-acetylneuraminate lyase YP_001732077.1 3468450 R 316385 CDS YP_001732078.1 170082758 6059247 complement(3469465..3470256) 1 NC_010473.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3470256 nanR 6059247 nanR Escherichia coli str. K-12 substr. DH10B transcriptional regulator NanR YP_001732078.1 3469465 R 316385 CDS YP_001732079.1 170082759 6060531 3470636..3472003 1 NC_010473.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD 3472003 dcuD 6060531 dcuD Escherichia coli str. K-12 substr. DH10B putative cryptic C4-dicarboxylate transporter DcuD YP_001732079.1 3470636 D 316385 CDS YP_001732080.1 170082760 6059223 complement(3472046..3472543) 1 NC_010473.1 ClpXP protease specificity-enhancing factor 3472543 sspB 6059223 sspB Escherichia coli str. K-12 substr. DH10B ClpXP protease specificity-enhancing factor YP_001732080.1 3472046 R 316385 CDS YP_001732081.1 170082761 6060941 complement(3472549..3473187) 1 NC_010473.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3473187 sspA 6060941 sspA Escherichia coli str. K-12 substr. DH10B stringent starvation protein A YP_001732081.1 3472549 R 316385 CDS YP_001732082.1 170082762 6059202 complement(3473582..3473974) 1 NC_010473.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3473974 rpsI 6059202 rpsI Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S9 YP_001732082.1 3473582 R 316385 CDS YP_001732083.1 170082763 6059129 complement(3473990..3474418) 1 NC_010473.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3474418 rplM 6059129 rplM Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L13 YP_001732083.1 3473990 R 316385 CDS YP_001732084.1 170082764 6059168 complement(3474637..3475764) 1 NC_010473.1 hypothetical protein 3475764 yhcM 6059168 yhcM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732084.1 3474637 R 316385 CDS YP_001732085.1 170082765 6061311 3475958..3476356 1 NC_010473.1 cytochrome d ubiquinol oxidase subunit III 3476356 yhcB 6061311 yhcB Escherichia coli str. K-12 substr. DH10B cytochrome d ubiquinol oxidase subunit III YP_001732085.1 3475958 D 316385 CDS YP_001732086.1 170082766 6059706 3476510..3477877 1 NC_010473.1 serine endoprotease 3477877 degQ 6059706 degQ Escherichia coli str. K-12 substr. DH10B serine endoprotease YP_001732086.1 3476510 D 316385 CDS YP_001732087.1 170082767 6062413 3477967..3479034 1 NC_010473.1 serine endoprotease 3479034 degS 6062413 degS Escherichia coli str. K-12 substr. DH10B serine endoprotease YP_001732087.1 3477967 D 316385 CDS YP_001732088.1 170082768 6059112 complement(3479097..3480035) 1 NC_010473.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3480035 mdh 6059112 mdh Escherichia coli str. K-12 substr. DH10B malate dehydrogenase YP_001732088.1 3479097 R 316385 CDS YP_001732089.1 170082769 6059090 3480470..3480940 1 NC_010473.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3480940 argR 6059090 argR Escherichia coli str. K-12 substr. DH10B arginine repressor YP_001732089.1 3480470 D 316385 CDS YP_001732090.1 170082770 6061457 3481305..3481568 1 NC_010473.1 hypothetical protein 3481568 yhcN 6061457 yhcN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732090.1 3481305 D 316385 CDS YP_001732091.1 170082771 6059045 complement(3481624..3481896) 1 NC_010473.1 barnase inhibitor 3481896 yhcO 6059045 yhcO Escherichia coli str. K-12 substr. DH10B barnase inhibitor YP_001732091.1 3481624 R 316385 CDS YP_001732092.1 170082772 6059066 complement(3483961..3484893) 1 NC_010473.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3484893 aaeA 6059066 aaeA Escherichia coli str. K-12 substr. DH10B p-hydroxybenzoic acid efflux subunit AaeA YP_001732092.1 3483961 R 316385 CDS YP_001732093.1 170082773 6059034 complement(3484901..3485104) 1 NC_010473.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3485104 aaeX 6059034 aaeX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732093.1 3484901 R 316385 CDS YP_001732094.1 170082774 6059519 3485287..3486216 1 NC_010473.1 putative DNA-binding transcriptional regulator 3486216 aaeR 6059519 aaeR Escherichia coli str. K-12 substr. DH10B putative DNA-binding transcriptional regulator YP_001732094.1 3485287 D 316385 CDS YP_001732095.1 170082775 6059006 complement(3486350..3487795) 1 NC_010473.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3487795 tldD 6059006 tldD Escherichia coli str. K-12 substr. DH10B protease TldD YP_001732095.1 3486350 R 316385 CDS YP_001732096.1 170082776 6058962 complement(3488225..3492025) 1 NC_010473.1 hypothetical protein 3492025 yhdP 6058962 yhdP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732096.1 3488225 R 316385 CDS YP_001732097.1 170082777 6061262 complement(3492093..3493562) 1 NC_010473.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3493562 rng 6061262 rng Escherichia coli str. K-12 substr. DH10B ribonuclease G YP_001732097.1 3492093 R 316385 CDS YP_001732098.1 170082778 6058930 complement(3493552..3494145) 1 NC_010473.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3494145 yhdE 6058930 yhdE Escherichia coli str. K-12 substr. DH10B Maf-like protein YP_001732098.1 3493552 R 316385 CDS YP_001732099.1 170082779 6059000 complement(3494154..3494642) 1 NC_010473.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3494642 mreD 6059000 mreD Escherichia coli str. K-12 substr. DH10B rod shape-determining protein MreD YP_001732099.1 3494154 R 316385 CDS YP_001732100.1 170082780 6058887 complement(3495811..3496854) 1 NC_010473.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3496854 mreB 6058887 mreB Escherichia coli str. K-12 substr. DH10B rod shape-determining protein MreB YP_001732100.1 3495811 R 316385 CDS YP_001732101.1 170082781 6059879 complement(3497159..3499099) 1 NC_010473.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3499099 yhdA 6059879 yhdA Escherichia coli str. K-12 substr. DH10B regulatory protein CsrD YP_001732101.1 3497159 R 316385 CDS YP_001732102.1 170082782 6058906 3499251..3500225 1 NC_010473.1 oxidoreductase, Zn-dependent and NAD(P)-binding 3500225 yhdH 6058906 yhdH Escherichia coli str. K-12 substr. DH10B oxidoreductase, Zn-dependent and NAD(P)-binding YP_001732102.1 3499251 D 316385 CDS YP_001732103.1 170082783 6058890 3501203..3501673 1 NC_010473.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3501673 accB 6058890 accB Escherichia coli str. K-12 substr. DH10B acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_001732103.1 3501203 D 316385 CDS YP_001732104.1 170082784 6058863 3501684..3503033 1 NC_010473.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3503033 accC 6058863 accC Escherichia coli str. K-12 substr. DH10B acetyl-CoA carboxylase biotin carboxylase subunit YP_001732104.1 3501684 D 316385 CDS YP_001732105.1 170082785 6058850 3503142..3503384 1 NC_010473.1 hypothetical protein 3503384 yhdT 6058850 yhdT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732105.1 3503142 D 316385 CDS YP_001732106.1 170082786 6058829 3503374..3504825 1 NC_010473.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3504825 panF 6058829 panF Escherichia coli str. K-12 substr. DH10B sodium/panthothenate symporter YP_001732106.1 3503374 D 316385 CDS YP_001732107.1 170082787 6058825 3504837..3505718 1 NC_010473.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3505718 prmA 6058825 prmA Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L11 methyltransferase YP_001732107.1 3504837 D 316385 CDS YP_001732108.1 170082788 6060085 3506047..3507012 1 NC_010473.1 tRNA-dihydrouridine synthase B 3507012 dusB 6060085 dusB Escherichia coli str. K-12 substr. DH10B tRNA-dihydrouridine synthase B YP_001732108.1 3506047 D 316385 CDS YP_001732109.1 170082789 6058830 3507038..3507334 1 NC_010473.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3507334 fis 6058830 fis Escherichia coli str. K-12 substr. DH10B DNA-binding protein Fis YP_001732109.1 3507038 D 316385 CDS YP_001732110.1 170082790 6060943 3507420..3508304 1 NC_010473.1 putative methyltransferase 3508304 yhdJ 6060943 yhdJ Escherichia coli str. K-12 substr. DH10B putative methyltransferase YP_001732110.1 3507420 D 316385 CDS YP_001732111.1 170082791 6058799 3508388..3508567 1 NC_010473.1 hypothetical protein 3508567 yhdU 6058799 yhdU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732111.1 3508388 D 316385 CDS YP_001732112.1 170082792 6058768 complement(3508570..3509232) 1 NC_010473.1 DNA-binding transcriptional regulator EnvR 3509232 envR 6058768 envR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator EnvR YP_001732112.1 3508570 R 316385 CDS YP_001732113.1 170082793 6058793 3509631..3510788 1 NC_010473.1 hypothetical protein 3510788 acrE 6058793 acrE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732113.1 3509631 D 316385 CDS YP_001732114.1 170082794 6058714 3510800..3513904 1 NC_010473.1 multidrug efflux system protein 3513904 acrF 6058714 acrF Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein YP_001732114.1 3510800 D 316385 CDS YP_001732115.1 170082795 6059438 3514157..3514378 1 NC_010473.1 outer membrane protein 3514378 yhdV 6059438 yhdV Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001732115.1 3514157 D 316385 CDS YP_001732116.1 170082796 6058747 3514916..3515833 1 NC_010473.1 amino-acid ABC transporter periplasmic-binding protein 3515833 yhdW 6058747 yhdW Escherichia coli str. K-12 substr. DH10B amino-acid ABC transporter periplasmic-binding protein YP_001732116.1 3514916 D 316385 CDS YP_001732117.1 170082797 6060901 3515901..3517082 1 NC_010473.1 amino-acid ABC transporter membrane protein 3517082 yhdX 6060901 yhdX Escherichia coli str. K-12 substr. DH10B amino-acid ABC transporter membrane protein YP_001732117.1 3515901 D 316385 CDS YP_001732118.1 170082798 6058728 3517092..3518195 1 NC_010473.1 amino-acid ABC transporter membrane protein 3518195 yhdY 6058728 yhdY Escherichia coli str. K-12 substr. DH10B amino-acid ABC transporter membrane protein YP_001732118.1 3517092 D 316385 CDS YP_001732119.1 170082799 6060792 3518203..3518961 1 NC_010473.1 amino-acid ABC transporter ATP-binding protein 3518961 yhdZ 6060792 yhdZ Escherichia coli str. K-12 substr. DH10B amino-acid ABC transporter ATP-binding protein YP_001732119.1 3518203 D 316385 CDS YP_001732120.1 170082800 6061316 3525003..3525557 1 NC_010473.1 hypothetical protein 3525557 yrdA 6061316 yrdA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732120.1 3525003 D 316385 CDS YP_001732121.1 170082801 6061950 complement(3525533..3525790) 1 NC_010473.1 hypothetical protein 3525790 yrdB 6061950 yrdB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732121.1 3525533 R 316385 CDS YP_001732122.1 170082802 6061872 complement(3525787..3526605) 1 NC_010473.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3526605 aroE 6061872 aroE Escherichia coli str. K-12 substr. DH10B shikimate 5-dehydrogenase YP_001732122.1 3525787 R 316385 CDS YP_001732123.1 170082803 6061541 complement(3526610..3527182) 1 NC_010473.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor 3527182 yrdC 6061541 yrdC Escherichia coli str. K-12 substr. DH10B putative ribosome maturation factor YP_001732123.1 3526610 R 316385 CDS YP_001732124.1 170082804 6061055 complement(3527187..3527729) 1 NC_010473.1 DNA topoisomerase 3527729 yrdD 6061055 yrdD Escherichia coli str. K-12 substr. DH10B DNA topoisomerase YP_001732124.1 3527187 R 316385 CDS YP_001732125.1 170082805 6061978 complement(3527758..3528231) 1 NC_010473.1 hypothetical protein 3528231 smg 6061978 smg Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732125.1 3527758 R 316385 CDS YP_001732126.1 170082806 6060918 complement(3528203..3529327) 1 NC_010473.1 DNA protecting protein DprA 3529327 smf 6060918 smf Escherichia coli str. K-12 substr. DH10B DNA protecting protein DprA YP_001732126.1 3528203 R 316385 CDS YP_001732127.1 170082807 6061433 3529457..3529966 1 NC_010473.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3529966 def 6061433 def Escherichia coli str. K-12 substr. DH10B peptide deformylase YP_001732127.1 3529457 D 316385 CDS YP_001732128.1 170082808 6059727 3529981..3530928 1 NC_010473.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3530928 fmt 6059727 fmt Escherichia coli str. K-12 substr. DH10B methionyl-tRNA formyltransferase YP_001732128.1 3529981 D 316385 CDS YP_001732129.1 170082809 6059531 3530974..3532263 1 NC_010473.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3532263 rsmB 6059531 rsmB Escherichia coli str. K-12 substr. DH10B 16S rRNA methyltransferase B YP_001732129.1 3530974 D 316385 CDS YP_001732130.1 170082810 6061307 3533791..3534201 1 NC_010473.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3534201 mscL 6061307 mscL Escherichia coli str. K-12 substr. DH10B large-conductance mechanosensitive channel YP_001732130.1 3533791 D 316385 CDS YP_001732131.1 170082811 6061819 complement(3534198..3534416) 1 NC_010473.1 hypothetical protein 3534416 yhdL 6061819 yhdL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732131.1 3534198 R 316385 CDS YP_001732132.1 170082812 6061557 complement(3534472..3534897) 1 NC_010473.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3534897 zntR 6061557 zntR Escherichia coli str. K-12 substr. DH10B zinc-responsive transcriptional regulator YP_001732132.1 3534472 R 316385 CDS YP_001732133.1 170082813 6061995 complement(3534908..3535276) 1 NC_010473.1 hypothetical protein 3535276 yhdN 6061995 yhdN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732133.1 3534908 R 316385 CDS YP_001732134.1 170082814 6058843 complement(3535383..3535766) 1 NC_010473.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3535766 rplQ 6058843 rplQ Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L17 YP_001732134.1 3535383 R 316385 CDS YP_001732135.1 170082815 6060938 complement(3535807..3536796) 1 NC_010473.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3536796 rpoA 6060938 rpoA Escherichia coli str. K-12 substr. DH10B DNA-directed RNA polymerase subunit alpha YP_001732135.1 3535807 R 316385 CDS YP_001732136.1 170082816 6059087 complement(3536822..3537442) 1 NC_010473.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3537442 rpsD 6059087 rpsD Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S4 YP_001732136.1 3536822 R 316385 CDS YP_001732137.1 170082817 6061116 complement(3537476..3537865) 1 NC_010473.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3537865 rpsK 6061116 rpsK Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S11 YP_001732137.1 3537476 R 316385 CDS YP_001732138.1 170082818 6061558 complement(3537882..3538238) 1 NC_010473.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3538238 rpsM 6061558 rpsM Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S13 YP_001732138.1 3537882 R 316385 CDS YP_001732139.1 170082819 6062198 complement(3538385..3538501) 1 NC_010473.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3538501 rpmJ 6062198 rpmJ Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L36 YP_001732139.1 3538385 R 316385 CDS YP_001732140.1 170082820 6059858 complement(3538533..3539864) 1 NC_010473.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3539864 secY 6059858 secY Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit SecY YP_001732140.1 3538533 R 316385 CDS YP_001732141.1 170082821 6059573 complement(3539872..3540306) 1 NC_010473.1 late assembly protein; 50S ribosomal protein L15 3540306 rplO 6059573 rplO Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L15 YP_001732141.1 3539872 R 316385 CDS YP_001732142.1 170082822 6059786 complement(3540310..3540489) 1 NC_010473.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3540489 rpmD 6059786 rpmD Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L30 YP_001732142.1 3540310 R 316385 CDS YP_001732143.1 170082823 6059582 complement(3540493..3540996) 1 NC_010473.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3540996 rpsE 6059582 rpsE Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S5 YP_001732143.1 3540493 R 316385 CDS YP_001732144.1 170082824 6059758 complement(3541011..3541364) 1 NC_010473.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3541364 rplR 6059758 rplR Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L18 YP_001732144.1 3541011 R 316385 CDS YP_001732145.1 170082825 6058937 complement(3541374..3541907) 1 NC_010473.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3541907 rplF 6058937 rplF Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L6 YP_001732145.1 3541374 R 316385 CDS YP_001732146.1 170082826 6059437 complement(3541920..3542312) 1 NC_010473.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3542312 rpsH 6059437 rpsH Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S8 YP_001732146.1 3541920 R 316385 CDS YP_001732147.1 170082827 6059078 complement(3542346..3542651) 1 NC_010473.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3542651 rpsN 6059078 rpsN Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S14 YP_001732147.1 3542346 R 316385 CDS YP_001732148.1 170082828 6059076 complement(3542666..3543205) 1 NC_010473.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3543205 rplE 6059076 rplE Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L5 YP_001732148.1 3542666 R 316385 CDS YP_001732149.1 170082829 6058945 complement(3543220..3543534) 1 NC_010473.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3543534 rplX 6058945 rplX Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L24 YP_001732149.1 3543220 R 316385 CDS YP_001732150.1 170082830 6059032 complement(3543545..3543916) 1 NC_010473.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3543916 rplN 6059032 rplN Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L14 YP_001732150.1 3543545 R 316385 CDS YP_001732151.1 170082831 6058892 complement(3544081..3544335) 1 NC_010473.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3544335 rpsQ 6058892 rpsQ Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S17 YP_001732151.1 3544081 R 316385 CDS YP_001732152.1 170082832 6059352 complement(3544335..3544526) 1 NC_010473.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3544526 rpmC 6059352 rpmC Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L29 YP_001732152.1 3544335 R 316385 CDS YP_001732153.1 170082833 6059491 complement(3544526..3544936) 1 NC_010473.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3544936 rplP 6059491 rplP Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L16 YP_001732153.1 3544526 R 316385 CDS YP_004770504.1 342516004 11031905 complement(3544949..3545650) 1 NC_010473.1 30S ribosomal protein S3 3545650 11031905 ECDH10B_p1 Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S3 YP_004770504.1 3544949 R 316385 CDS YP_001732154.1 170082834 6059022 complement(3545668..3546000) 1 NC_010473.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3546000 rplV 6059022 rplV Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L22 YP_001732154.1 3545668 R 316385 CDS YP_001732155.1 170082835 6058817 complement(3546015..3546293) 1 NC_010473.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3546293 rpsS 6058817 rpsS Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S19 YP_001732155.1 3546015 R 316385 CDS YP_001732156.1 170082836 6061209 complement(3546310..3547131) 1 NC_010473.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3547131 rplB 6061209 rplB Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L2 YP_001732156.1 3546310 R 316385 CDS YP_001732157.1 170082837 6058860 complement(3547149..3547451) 1 NC_010473.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3547451 rplW 6058860 rplW Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L23 YP_001732157.1 3547149 R 316385 CDS YP_001732158.1 170082838 6058745 complement(3547448..3548053) 1 NC_010473.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3548053 rplD 6058745 rplD Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L4 YP_001732158.1 3547448 R 316385 CDS YP_001732159.1 170082839 6059985 complement(3548064..3548693) 1 NC_010473.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3548693 rplC 6059985 rplC Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L3 YP_001732159.1 3548064 R 316385 CDS YP_001732160.1 170082840 6058272 complement(3548726..3549037) 1 NC_010473.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3549037 rpsJ 6058272 rpsJ Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S10 YP_001732160.1 3548726 R 316385 CDS YP_001732161.1 170082841 6060724 complement(3549275..3549694) 1 NC_010473.1 calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO 3549694 pioO 6060724 pioO Escherichia coli str. K-12 substr. DH10B chromosome replication protein PioO YP_001732161.1 3549275 R 316385 CDS YP_001732162.1 170082842 6059183 complement(3549696..3551165) 1 NC_010473.1 general secretory pathway component, cryptic 3551165 gspA 6059183 gspA Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732162.1 3549696 R 316385 CDS YP_001732163.1 170082843 6062353 3551345..3552160 1 NC_010473.1 general secretory pathway component, cryptic 3552160 gspC 6062353 gspC Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732163.1 3551345 D 316385 CDS YP_001732164.1 170082844 6061717 3552144..3554096 1 NC_010473.1 general secretory pathway component, cryptic 3554096 gspD 6061717 gspD Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732164.1 3552144 D 316385 CDS YP_001732165.1 170082845 6060978 3554106..3555587 1 NC_010473.1 general secretory pathway component, cryptic 3555587 gspE 6060978 gspE Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732165.1 3554106 D 316385 CDS YP_001732166.1 170082846 6062144 3555584..3556780 1 NC_010473.1 general secretory pathway component, cryptic 3556780 gspF 6062144 gspF Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732166.1 3555584 D 316385 CDS YP_001732167.1 170082847 6060555 3556790..3557227 1 NC_010473.1 pseudopilin, cryptic, general secretion pathway 3557227 gspG 6060555 gspG Escherichia coli str. K-12 substr. DH10B pseudopilin, cryptic, general secretion pathway YP_001732167.1 3556790 D 316385 CDS YP_001732168.1 170082848 6061104 3557235..3557744 1 NC_010473.1 general secretory pathway component, cryptic 3557744 gspH 6061104 gspH Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732168.1 3557235 D 316385 CDS YP_001732169.1 170082849 6061406 3557741..3558118 1 NC_010473.1 general secretory pathway component, cryptic 3558118 gspI 6061406 gspI Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732169.1 3557741 D 316385 CDS YP_001732170.1 170082850 6061893 3558111..3558698 1 NC_010473.1 general secretory pathway component, cryptic 3558698 gspJ 6061893 gspJ Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732170.1 3558111 D 316385 CDS YP_001732171.1 170082851 6061780 3558691..3559674 1 NC_010473.1 general secretory pathway component, cryptic 3559674 gspK 6061780 gspK Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732171.1 3558691 D 316385 CDS YP_001732172.1 170082852 6059862 3559689..3560852 1 NC_010473.1 general secretory pathway component, cryptic 3560852 gspL 6059862 gspL Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732172.1 3559689 D 316385 CDS YP_001732173.1 170082853 6058075 3560849..3561310 1 NC_010473.1 general secretory pathway component, cryptic 3561310 gspM 6058075 gspM Escherichia coli str. K-12 substr. DH10B general secretory pathway component, cryptic YP_001732173.1 3560849 D 316385 CDS YP_001732174.1 170082854 6060472 3561310..3561987 1 NC_010473.1 bifunctional prepilin leader peptidase and methylase 3561987 gspO 6060472 gspO Escherichia coli str. K-12 substr. DH10B bifunctional prepilin leader peptidase and methylase YP_001732174.1 3561310 D 316385 CDS YP_001732175.1 170082855 6060487 complement(3562016..3562492) 1 NC_010473.1 iron storage protein; bacterioferritin 3562492 bfr 6060487 bfr Escherichia coli str. K-12 substr. DH10B bacterioferritin YP_001732175.1 3562016 R 316385 CDS YP_001732176.1 170082856 6061905 complement(3562564..3562758) 1 NC_010473.1 bacterioferritin-associated ferredoxin 3562758 bfd 6061905 bfd Escherichia coli str. K-12 substr. DH10B bacterioferritin-associated ferredoxin YP_001732176.1 3562564 R 316385 CDS YP_001732177.1 170082857 6061804 complement(3565912..3567096) 1 NC_010473.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3567096 tufA 6061804 tufA Escherichia coli str. K-12 substr. DH10B elongation factor Tu YP_001732177.1 3565912 R 316385 CDS YP_001732178.1 170082858 6058329 complement(3567167..3569281) 1 NC_010473.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3569281 fusA 6058329 fusA Escherichia coli str. K-12 substr. DH10B elongation factor G YP_001732178.1 3567167 R 316385 CDS YP_001732179.1 170082859 6059670 complement(3569309..3569848) 1 NC_010473.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3569848 rpsG 6059670 rpsG Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S7 YP_001732179.1 3569309 R 316385 CDS YP_004770505.1 342516005 11031906 complement(3569945..3570319) 1 NC_010473.1 30S ribosomal protein S12 3570319 11031906 ECDH10B_p2 Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S12 YP_004770505.1 3569945 R 316385 CDS YP_001732180.1 170082860 6059581 complement(3570445..3570732) 1 NC_010473.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3570732 yheL 6059581 yheL Escherichia coli str. K-12 substr. DH10B sulfur transfer complex subunit TusB YP_001732180.1 3570445 R 316385 CDS YP_001732181.1 170082861 6059423 complement(3570740..3571099) 1 NC_010473.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3571099 yheM 6059423 yheM Escherichia coli str. K-12 substr. DH10B sulfur relay protein TusC YP_001732181.1 3570740 R 316385 CDS YP_001732182.1 170082862 6059427 complement(3571099..3571485) 1 NC_010473.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3571485 yheN 6059427 yheN Escherichia coli str. K-12 substr. DH10B sulfur transfer complex subunit TusD YP_001732182.1 3571099 R 316385 CDS YP_001732183.1 170082863 6059399 complement(3571485..3572207) 1 NC_010473.1 DNA-binding transcriptional regulator 3572207 yheO 6059399 yheO Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732183.1 3571485 R 316385 CDS YP_001732184.1 170082864 6059064 complement(3572374..3573186) 1 NC_010473.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3573186 fkpA 6059064 fkpA Escherichia coli str. K-12 substr. DH10B FKBP-type peptidyl-prolyl cis-trans isomerase YP_001732184.1 3572374 R 316385 CDS YP_001732185.1 170082865 6059232 3573407..3573625 1 NC_010473.1 hypothetical protein 3573625 slyX 6059232 slyX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732185.1 3573407 D 316385 CDS YP_001732186.1 170082866 6059578 complement(3573674..3574264) 1 NC_010473.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3574264 slyD 6059578 slyD Escherichia coli str. K-12 substr. DH10B FKBP-type peptidyl-prolyl cis-trans isomerase YP_001732186.1 3573674 R 316385 CDS YP_001732187.1 170082867 6060251 complement(3574359..3574559) 1 NC_010473.1 hypothetical protein 3574559 yheV 6060251 yheV Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732187.1 3574359 R 316385 CDS YP_001732188.1 170082868 6060313 complement(3574569..3576374) 1 NC_010473.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3576374 kefB 6060313 kefB Escherichia coli str. K-12 substr. DH10B glutathione-regulated potassium-efflux system protein KefB YP_001732188.1 3574569 R 316385 CDS YP_001732189.1 170082869 6059138 complement(3576374..3576928) 1 NC_010473.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3576928 kefG 6059138 kefG Escherichia coli str. K-12 substr. DH10B glutathione-regulated potassium-efflux system ancillary protein KefG YP_001732189.1 3576374 R 316385 CDS YP_001732190.1 170082870 6060384 3577056..3578969 1 NC_010473.1 putative ABC transporter ATP-binding protein 3578969 yheS 6060384 yheS Escherichia coli str. K-12 substr. DH10B putative ABC transporter ATP-binding protein YP_001732190.1 3577056 D 316385 CDS YP_001732191.1 170082871 6058846 3578969..3579991 1 NC_010473.1 putative hydrolase 3579991 yheT 6058846 yheT Escherichia coli str. K-12 substr. DH10B putative hydrolase YP_001732191.1 3578969 D 316385 CDS YP_001732192.1 170082872 6058739 3579985..3580203 1 NC_010473.1 hypothetical protein 3580203 yheU 6058739 yheU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732192.1 3579985 D 316385 CDS YP_001732193.1 170082873 6060405 3580257..3581126 1 NC_010473.1 phosphoribulokinase 3581126 prkB 6060405 prkB Escherichia coli str. K-12 substr. DH10B phosphoribulokinase YP_001732193.1 3580257 D 316385 CDS YP_001732194.1 170082874 6058926 complement(3581181..3581585) 1 NC_010473.1 hypothetical protein 3581585 yhfA 6058926 yhfA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732194.1 3581181 R 316385 CDS YP_001732195.1 170082875 6058677 3581887..3582519 1 NC_010473.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3582519 crp 6058677 crp Escherichia coli str. K-12 substr. DH10B cAMP-regulatory protein YP_001732195.1 3581887 D 316385 CDS YP_001732196.1 170082876 6058992 3582558..3584660 1 NC_010473.1 inner membrane protein 3584660 yhfK 6058992 yhfK Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732196.1 3582558 D 316385 CDS YP_001732197.1 170082877 6058980 complement(3584727..3585947) 1 NC_010473.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 3585947 argD 6058980 argD Escherichia coli str. K-12 substr. DH10B bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_001732197.1 3584727 R 316385 CDS YP_001732198.1 170082878 6059154 complement(3586033..3586596) 1 NC_010473.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3586596 pabA 6059154 pabA Escherichia coli str. K-12 substr. DH10B para-aminobenzoate synthase component II YP_001732198.1 3586033 R 316385 CDS YP_001732199.1 170082879 6059553 complement(3586628..3587230) 1 NC_010473.1 cell filamentation protein Fic 3587230 fic 6059553 fic Escherichia coli str. K-12 substr. DH10B cell filamentation protein Fic YP_001732199.1 3586628 R 316385 CDS YP_001732200.1 170082880 6059760 complement(3587220..3587387) 1 NC_010473.1 hypothetical protein 3587387 yhfG 6059760 yhfG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732200.1 3587220 R 316385 CDS YP_001732201.1 170082881 6060439 complement(3587492..3588064) 1 NC_010473.1 peptidyl-prolyl cis-trans isomerase A 3588064 ppiA 6060439 ppiA Escherichia coli str. K-12 substr. DH10B peptidyl-prolyl cis-trans isomerase A YP_001732201.1 3587492 R 316385 CDS YP_001732202.1 170082882 6058644 3588335..3589516 1 NC_010473.1 hypothetical protein 3589516 tsgA 6058644 tsgA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732202.1 3588335 D 316385 CDS YP_001732203.1 170082883 6058662 3589778..3592321 1 NC_010473.1 nitrite reductase, large subunit, NAD(P)H-binding 3592321 nirB 6058662 nirB Escherichia coli str. K-12 substr. DH10B nitrite reductase, large subunit, NAD(P)H-binding YP_001732203.1 3589778 D 316385 CDS YP_001732204.1 170082884 6059320 3592318..3592644 1 NC_010473.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3592644 nirD 6059320 nirD Escherichia coli str. K-12 substr. DH10B nitrite reductase small subunit YP_001732204.1 3592318 D 316385 CDS YP_001732205.1 170082885 6059572 3592770..3593576 1 NC_010473.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3593576 nirC 6059572 nirC Escherichia coli str. K-12 substr. DH10B nitrite transporter NirC YP_001732205.1 3592770 D 316385 CDS YP_001732206.1 170082886 6059603 3593595..3594968 1 NC_010473.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3594968 cysG 6059603 cysG Escherichia coli str. K-12 substr. DH10B siroheme synthase YP_001732206.1 3593595 D 316385 CDS YP_001732207.1 170082887 6059815 3595215..3595382 1 NC_010473.1 secreted peptide 3595382 yhfL 6059815 yhfL Escherichia coli str. K-12 substr. DH10B secreted peptide YP_001732207.1 3595215 D 316385 CDS YP_001732208.1 170082888 6059639 3595677..3597014 1 NC_010473.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; putative fructoselysine transporter 3597014 frlA 6059639 frlA Escherichia coli str. K-12 substr. DH10B putative fructoselysine transporter YP_001732208.1 3595677 D 316385 CDS YP_001732209.1 170082889 6059657 3597035..3598057 1 NC_010473.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 3598057 frlB 6059657 frlB Escherichia coli str. K-12 substr. DH10B fructoselysine-6-P-deglycase YP_001732209.1 3597035 D 316385 CDS YP_001732210.1 170082890 6059666 3598107..3598937 1 NC_010473.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 3598937 frlC 6059666 frlC Escherichia coli str. K-12 substr. DH10B fructoselysine 3-epimerase YP_001732210.1 3598107 D 316385 CDS YP_001732211.1 170082891 6059973 3598934..3599719 1 NC_010473.1 fructoselysine 6-kinase 3599719 frlD 6059973 frlD Escherichia coli str. K-12 substr. DH10B fructoselysine 6-kinase YP_001732211.1 3598934 D 316385 CDS YP_001732212.1 170082892 6060003 3599819..3600550 1 NC_010473.1 may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3600550 frlR 6060003 frlR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator FrlR YP_001732212.1 3599819 D 316385 CDS YP_001732213.1 170082893 6062305 complement(3600702..3601787) 1 NC_010473.1 hypothetical protein 3601787 yhfS 6062305 yhfS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732213.1 3600702 R 316385 CDS YP_001732214.1 170082894 6061997 complement(3601799..3603103) 1 NC_010473.1 inner membrane protein 3603103 yhfT 6061997 yhfT Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732214.1 3601799 R 316385 CDS YP_001732215.1 170082895 6061683 complement(3603115..3603468) 1 NC_010473.1 hypothetical protein 3603468 yhfU 6061683 yhfU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732215.1 3603115 R 316385 CDS YP_001732216.1 170082896 6059017 complement(3603479..3604357) 1 NC_010473.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase 3604357 php 6059017 php Escherichia coli str. K-12 substr. DH10B putative hydrolase YP_001732216.1 3603479 R 316385 CDS YP_001732217.1 170082897 6061261 complement(3604354..3605580) 1 NC_010473.1 putative mutase 3605580 yhfW 6061261 yhfW Escherichia coli str. K-12 substr. DH10B putative mutase YP_001732217.1 3604354 R 316385 CDS YP_001732218.1 170082898 6061107 complement(3605580..3606743) 1 NC_010473.1 amino acid racemase 3606743 yhfX 6061107 yhfX Escherichia coli str. K-12 substr. DH10B amino acid racemase YP_001732218.1 3605580 R 316385 CDS YP_001732219.1 170082899 6060985 complement(3606827..3607189) 1 NC_010473.1 hypothetical protein 3607189 yhfY 6060985 yhfY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732219.1 3606827 R 316385 CDS YP_001732220.1 170082900 6060948 complement(3607206..3608111) 1 NC_010473.1 hypothetical protein 3608111 yhfZ 6060948 yhfZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732220.1 3607206 R 316385 CDS YP_001732221.1 170082901 6060927 complement(3608401..3609405) 1 NC_010473.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3609405 trpS 6060927 trpS Escherichia coli str. K-12 substr. DH10B tryptophanyl-tRNA synthetase YP_001732221.1 3608401 R 316385 CDS YP_001732222.1 170082902 6060759 complement(3609398..3610156) 1 NC_010473.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3610156 gph 6060759 gph Escherichia coli str. K-12 substr. DH10B phosphoglycolate phosphatase YP_001732222.1 3609398 R 316385 CDS YP_001732223.1 170082903 6060705 complement(3610149..3610826) 1 NC_010473.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3610826 rpe 6060705 rpe Escherichia coli str. K-12 substr. DH10B ribulose-phosphate 3-epimerase YP_001732223.1 3610149 R 316385 CDS YP_001732224.1 170082904 6060593 complement(3610844..3611680) 1 NC_010473.1 DNA adenine methylase 3611680 dam 6060593 dam Escherichia coli str. K-12 substr. DH10B DNA adenine methylase YP_001732224.1 3610844 R 316385 CDS YP_001732225.1 170082905 6059534 complement(3611787..3613073) 1 NC_010473.1 hypothetical protein 3613073 damX 6059534 damX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732225.1 3611787 R 316385 CDS YP_001732226.1 170082906 6058405 complement(3613165..3614253) 1 NC_010473.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3614253 aroB 6058405 aroB Escherichia coli str. K-12 substr. DH10B 3-dehydroquinate synthase YP_001732226.1 3613165 R 316385 CDS YP_001732227.1 170082907 6058602 complement(3614310..3614831) 1 NC_010473.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3614831 aroK 6058602 aroK Escherichia coli str. K-12 substr. DH10B shikimate kinase I YP_001732227.1 3614310 R 316385 CDS YP_001732228.1 170082908 6058164 complement(3615232..3616470) 1 NC_010473.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3616470 hofQ 6058164 hofQ Escherichia coli str. K-12 substr. DH10B outer membrane porin HofQ YP_001732228.1 3615232 R 316385 CDS YP_001732229.1 170082909 6058372 complement(3616382..3616786) 1 NC_010473.1 hypothetical protein 3616786 yrfA 6058372 yrfA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732229.1 3616382 R 316385 CDS YP_001732230.1 170082910 6058460 complement(3616776..3617216) 1 NC_010473.1 hypothetical protein 3617216 yrfB 6058460 yrfB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732230.1 3616776 R 316385 CDS YP_001732231.1 170082911 6058507 complement(3617200..3617739) 1 NC_010473.1 fimbrial assembly protein 3617739 yrfC 6058507 yrfC Escherichia coli str. K-12 substr. DH10B fimbrial assembly protein YP_001732231.1 3617200 R 316385 CDS YP_001732232.1 170082912 6058167 complement(3617739..3618518) 1 NC_010473.1 pilus assembly protein 3618518 yrfD 6058167 yrfD Escherichia coli str. K-12 substr. DH10B pilus assembly protein YP_001732232.1 3617739 R 316385 CDS YP_001732233.1 170082913 6060462 3618638..3621190 1 NC_010473.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3621190 mrcA 6060462 mrcA Escherichia coli str. K-12 substr. DH10B peptidoglycan synthetase YP_001732233.1 3618638 D 316385 CDS YP_001732234.1 170082914 6059292 complement(3621356..3621916) 1 NC_010473.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3621916 nudE 6059292 nudE Escherichia coli str. K-12 substr. DH10B ADP-ribose diphosphatase NudE YP_001732234.1 3621356 R 316385 CDS YP_001732235.1 170082915 6059286 3622236..3624371 1 NC_010473.1 inner membrane protein 3624371 yrfF 6059286 yrfF Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732235.1 3622236 D 316385 CDS YP_001732236.1 170082916 6059623 3624436..3625104 1 NC_010473.1 hydrolase 3625104 yrfG 6059623 yrfG Escherichia coli str. K-12 substr. DH10B hydrolase YP_001732236.1 3624436 D 316385 CDS YP_001732237.1 170082917 6059683 3625115..3625516 1 NC_010473.1 ribosome-associated heat shock protein Hsp15 3625516 hslR 6059683 hslR Escherichia coli str. K-12 substr. DH10B ribosome-associated heat shock protein Hsp15 YP_001732237.1 3625115 D 316385 CDS YP_001732238.1 170082918 6058587 3625541..3626419 1 NC_010473.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3626419 hslO 6058587 hslO Escherichia coli str. K-12 substr. DH10B Hsp33-like chaperonin YP_001732238.1 3625541 D 316385 CDS YP_001732239.1 170082919 6062196 complement(3626482..3628206) 1 NC_010473.1 inner membrane protein 3628206 yhgE 6062196 yhgE Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732239.1 3626482 R 316385 CDS YP_001732240.1 170082920 6062153 3628585..3630207 1 NC_010473.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3630207 pck 6062153 pck Escherichia coli str. K-12 substr. DH10B phosphoenolpyruvate carboxykinase YP_001732240.1 3628585 D 316385 CDS YP_001732241.1 170082921 6062092 complement(3630283..3631635) 1 NC_010473.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3631635 envZ 6062092 envZ Escherichia coli str. K-12 substr. DH10B osmolarity sensor protein YP_001732241.1 3630283 R 316385 CDS YP_001732242.1 170082922 6062072 complement(3631632..3632351) 1 NC_010473.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3632351 ompR 6062072 ompR Escherichia coli str. K-12 substr. DH10B osmolarity response regulator YP_001732242.1 3631632 R 316385 CDS YP_001732243.1 170082923 6061973 3632579..3633055 1 NC_010473.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3633055 greB 6061973 greB Escherichia coli str. K-12 substr. DH10B transcription elongation factor GreB YP_001732243.1 3632579 D 316385 CDS YP_001732244.1 170082924 6061974 3633152..3635473 1 NC_010473.1 transcriptional accessory protein 3635473 yhgF 6061974 yhgF Escherichia coli str. K-12 substr. DH10B transcriptional accessory protein YP_001732244.1 3633152 D 316385 CDS YP_001732245.1 170082925 6061832 3635930..3636157 1 NC_010473.1 ferrous iron transport protein A 3636157 feoA 6061832 feoA Escherichia coli str. K-12 substr. DH10B ferrous iron transport protein A YP_001732245.1 3635930 D 316385 CDS YP_001732246.1 170082926 6061692 3636174..3638495 1 NC_010473.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3638495 feoB 6061692 feoB Escherichia coli str. K-12 substr. DH10B ferrous iron transport protein B YP_001732246.1 3636174 D 316385 CDS YP_001732247.1 170082927 6061706 3638495..3638731 1 NC_010473.1 DNA-binding transcriptional regulator 3638731 yhgG 6061706 yhgG Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732247.1 3638495 D 316385 CDS YP_001732248.1 170082928 6061636 complement(3639841..3640611) 1 NC_010473.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3640611 bioH 6061636 bioH Escherichia coli str. K-12 substr. DH10B carboxylesterase BioH YP_001732248.1 3639841 R 316385 CDS YP_001732249.1 170082929 6061614 3640649..3641332 1 NC_010473.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3641332 gntX 6061614 gntX Escherichia coli str. K-12 substr. DH10B gluconate periplasmic binding protein YP_001732249.1 3640649 D 316385 CDS YP_001732250.1 170082930 6061539 3641391..3641966 1 NC_010473.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 3641966 gntY 6061539 gntY Escherichia coli str. K-12 substr. DH10B putative DNA uptake protein YP_001732250.1 3641391 D 316385 CDS YP_001732251.1 170082931 6061461 3642326..3643642 1 NC_010473.1 gluconate transporter, high-affinity GNT I system 3643642 gntT 6061461 gntT Escherichia coli str. K-12 substr. DH10B gluconate transporter, high-affinity GNT I system YP_001732251.1 3642326 D 316385 CDS YP_001732252.1 170082932 6061510 complement(3643753..3645837) 1 NC_010473.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3645837 malQ 6061510 malQ Escherichia coli str. K-12 substr. DH10B 4-alpha-glucanotransferase YP_001732252.1 3643753 R 316385 CDS YP_001732253.1 170082933 6061487 complement(3645847..3648240) 1 NC_010473.1 maltodextrin phosphorylase 3648240 malP 6061487 malP Escherichia coli str. K-12 substr. DH10B maltodextrin phosphorylase YP_001732253.1 3645847 R 316385 CDS YP_001732254.1 170082934 6061359 3648852..3651557 1 NC_010473.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3651557 malT 6061359 malT Escherichia coli str. K-12 substr. DH10B transcriptional regulator MalT YP_001732254.1 3648852 D 316385 CDS YP_001732255.1 170082935 6061384 complement(3651600..3652616) 1 NC_010473.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3652616 rtcA 6061384 rtcA Escherichia coli str. K-12 substr. DH10B RNA 3'-terminal-phosphate cyclase YP_001732255.1 3651600 R 316385 CDS YP_001732256.1 170082936 6061312 complement(3652620..3653846) 1 NC_010473.1 hypothetical protein 3653846 rtcB 6061312 rtcB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732256.1 3652620 R 316385 CDS YP_001732257.1 170082937 6061333 3654035..3655633 1 NC_010473.1 sigma 54-dependent transcriptional regulator of rtcBA expression 3655633 rtcR 6061333 rtcR Escherichia coli str. K-12 substr. DH10B sigma 54-dependent transcriptional regulator of rtcBA expression YP_001732257.1 3654035 D 316385 CDS YP_001732258.1 170082938 6061191 complement(3655615..3656373) 1 NC_010473.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3656373 glpR 6061191 glpR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor GlpR YP_001732258.1 3655615 R 316385 CDS YP_001732259.1 170082939 6061251 complement(3656390..3657220) 1 NC_010473.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3657220 glpG 6061251 glpG Escherichia coli str. K-12 substr. DH10B intramembrane serine protease GlpG YP_001732259.1 3656390 R 316385 CDS YP_001732260.1 170082940 6061078 complement(3657265..3657591) 1 NC_010473.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3657591 glpE 6061078 glpE Escherichia coli str. K-12 substr. DH10B thiosulfate sulfurtransferase YP_001732260.1 3657265 R 316385 CDS YP_001732261.1 170082941 6061051 3657781..3659286 1 NC_010473.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3659286 glpD 6061051 glpD Escherichia coli str. K-12 substr. DH10B glycerol-3-phosphate dehydrogenase YP_001732261.1 3657781 D 316385 CDS YP_001732262.1 170082942 6061043 complement(3659492..3659773) 1 NC_010473.1 hypothetical protein 3659773 yzgL 6061043 yzgL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732262.1 3659492 R 316385 CDS YP_001732263.1 170082943 6061049 complement(3659902..3662349) 1 NC_010473.1 glycogen phosphorylase 3662349 glgP 6061049 glgP Escherichia coli str. K-12 substr. DH10B glycogen phosphorylase YP_001732263.1 3659902 R 316385 CDS YP_001732264.1 170082944 6060955 complement(3662368..3663801) 1 NC_010473.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3663801 glgA 6060955 glgA Escherichia coli str. K-12 substr. DH10B glycogen synthase YP_001732264.1 3662368 R 316385 CDS YP_001732265.1 170082945 6060987 complement(3663801..3665096) 1 NC_010473.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3665096 glgC 6060987 glgC Escherichia coli str. K-12 substr. DH10B glucose-1-phosphate adenylyltransferase YP_001732265.1 3663801 R 316385 CDS YP_001732266.1 170082946 6060912 complement(3665114..3667087) 1 NC_010473.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 3667087 glgX 6060912 glgX Escherichia coli str. K-12 substr. DH10B glycogen debranching protein YP_001732266.1 3665114 R 316385 CDS YP_001732267.1 170082947 6060898 complement(3667084..3669270) 1 NC_010473.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 3669270 glgB 6060898 glgB Escherichia coli str. K-12 substr. DH10B glycogen branching protein YP_001732267.1 3667084 R 316385 CDS YP_001732268.1 170082948 6060816 complement(3669543..3670646) 1 NC_010473.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 3670646 asd 6060816 asd Escherichia coli str. K-12 substr. DH10B aspartate-semialdehyde dehydrogenase YP_001732268.1 3669543 R 316385 CDS YP_001732269.1 170082949 6060337 3670839..3671432 1 NC_010473.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 3671432 yhgN 6060337 yhgN Escherichia coli str. K-12 substr. DH10B putative dITP- and XTP- hydrolase YP_001732269.1 3670839 D 316385 CDS YP_001732270.1 170082950 6060691 complement(3671489..3672829) 1 NC_010473.1 low affinity gluconate transporter 3672829 gntU 6060691 gntU Escherichia coli str. K-12 substr. DH10B low affinity gluconate transporter YP_001732270.1 3671489 R 316385 CDS YP_001732271.1 170082951 6060707 complement(3672833..3673360) 1 NC_010473.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 3673360 gntK 6060707 gntK Escherichia coli str. K-12 substr. DH10B gluconate kinase YP_001732271.1 3672833 R 316385 CDS YP_001732272.1 170082952 6060554 complement(3673499..3674494) 1 NC_010473.1 DNA-binding transcriptional repressor 3674494 gntR 6060554 gntR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor YP_001732272.1 3673499 R 316385 CDS YP_001732273.1 170082953 6060269 complement(3674718..3675413) 1 NC_010473.1 hypothetical protein 3675413 yhhW 6060269 yhhW Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732273.1 3674718 R 316385 CDS YP_001732274.1 170082954 6062169 complement(3675536..3676573) 1 NC_010473.1 putative dehydrogenase 3676573 yhhX 6062169 yhhX Escherichia coli str. K-12 substr. DH10B putative dehydrogenase YP_001732274.1 3675536 R 316385 CDS YP_001732275.1 170082955 6058979 3676906..3677394 1 NC_010473.1 YhhY; regulated by the fur regulator; unknown function; putative acetyltransferase YhhY 3677394 yhhY 6058979 yhhY Escherichia coli str. K-12 substr. DH10B putative acetyltransferase YhhY YP_001732275.1 3676906 D 316385 CDS YP_001732276.1 170082956 6060660 3677631..3678809 1 NC_010473.1 hypothetical protein 3678809 yhhZ 6060660 yhhZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732276.1 3677631 D 316385 CDS YP_001732277.1 170082957 6062093 3678809..3679222 1 NC_010473.1 hypothetical protein 3679222 yrhA 6062093 yrhA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732277.1 3678809 D 316385 CDS YP_001732278.1 170082958 6061072 3679251..3679526 1 NC_010473.1 IS1 repressor protein InsA 3679526 insA-6 6061072 insA-6 Escherichia coli str. K-12 substr. DH10B IS1 repressor protein InsA YP_001732278.1 3679251 D 316385 CDS YP_001732279.1 170082959 6061027 3679445..3679948 1 NC_010473.1 IS1 transposase InsAB' 3679948 insB-6 6061027 insB-6 Escherichia coli str. K-12 substr. DH10B IS1 transposase InsAB' YP_001732279.1 3679445 D 316385 CDS YP_001732280.1 170082960 6062067 3680527..3680811 1 NC_010473.1 hypothetical protein 3680811 yrhB 6062067 yrhB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732280.1 3680527 D 316385 CDS YP_001732281.1 170082961 6061045 complement(3680849..3682591) 1 NC_010473.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 3682591 ggt 6061045 ggt Escherichia coli str. K-12 substr. DH10B gamma-glutamyltranspeptidase YP_001732281.1 3680849 R 316385 CDS YP_001732282.1 170082962 6062017 3682711..3683151 1 NC_010473.1 hypothetical protein 3683151 yhhA 6062017 yhhA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732282.1 3682711 D 316385 CDS YP_001732283.1 170082963 6062029 complement(3683138..3683881) 1 NC_010473.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 3683881 ugpQ 6062029 ugpQ Escherichia coli str. K-12 substr. DH10B glycerophosphodiester phosphodiesterase YP_001732283.1 3683138 R 316385 CDS YP_001732284.1 170082964 6061968 complement(3683878..3684948) 1 NC_010473.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 3684948 ugpC 6061968 ugpC Escherichia coli str. K-12 substr. DH10B glycerol-3-phosphate transporter ATP-binding subunit YP_001732284.1 3683878 R 316385 CDS YP_001732285.1 170082965 6061017 complement(3684950..3685795) 1 NC_010473.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 3685795 ugpE 6061017 ugpE Escherichia coli str. K-12 substr. DH10B glycerol-3-phosphate transporter membrane protein YP_001732285.1 3684950 R 316385 CDS YP_001732286.1 170082966 6061006 complement(3685792..3686679) 1 NC_010473.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 3686679 ugpA 6061006 ugpA Escherichia coli str. K-12 substr. DH10B glycerol-3-phosphate transporter permease YP_001732286.1 3685792 R 316385 CDS YP_001732287.1 170082967 6060999 complement(3686777..3688093) 1 NC_010473.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 3688093 ugpB 6060999 ugpB Escherichia coli str. K-12 substr. DH10B glycerol-3-phosphate transporter periplasmic binding protein YP_001732287.1 3686777 R 316385 CDS YP_001732288.1 170082968 6061919 complement(3688492..3689205) 1 NC_010473.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3689205 livF 6061919 livF Escherichia coli str. K-12 substr. DH10B leucine/isoleucine/valine transporter ATP-binding subunit YP_001732288.1 3688492 R 316385 CDS YP_001732289.1 170082969 6061984 complement(3689207..3689974) 1 NC_010473.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3689974 livG 6061984 livG Escherichia coli str. K-12 substr. DH10B leucine/isoleucine/valine transporter ATP-binding subunit YP_001732289.1 3689207 R 316385 CDS YP_001732290.1 170082970 6060932 complement(3689971..3691248) 1 NC_010473.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 3691248 livM 6060932 livM Escherichia coli str. K-12 substr. DH10B leucine/isoleucine/valine transporter permease subunit YP_001732290.1 3689971 R 316385 CDS YP_001732291.1 170082971 6060794 complement(3691245..3692171) 1 NC_010473.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 3692171 livH 6060794 livH Escherichia coli str. K-12 substr. DH10B branched-chain amino acid transporter permease subunit LivH YP_001732291.1 3691245 R 316385 CDS YP_001732292.1 170082972 6061623 complement(3692219..3693328) 1 NC_010473.1 leucine ABC transporter periplasmic-binding component 3693328 livK 6061623 livK Escherichia coli str. K-12 substr. DH10B leucine ABC transporter periplasmic-binding component YP_001732292.1 3692219 R 316385 CDS YP_001732293.1 170082973 6061630 3693752..3694135 1 NC_010473.1 hypothetical protein 3694135 yhhK 6061630 yhhK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732293.1 3693752 D 316385 CDS YP_001732294.1 170082974 6061574 complement(3694323..3695426) 1 NC_010473.1 leucine/isoleucine/valine ABC transporter periplasmic-binding component 3695426 livJ 6061574 livJ Escherichia coli str. K-12 substr. DH10B leucine/isoleucine/valine ABC transporter periplasmic-binding component YP_001732294.1 3694323 R 316385 CDS YP_001732295.1 170082975 6061532 complement(3695697..3696551) 1 NC_010473.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3696551 rpoH 6061532 rpoH Escherichia coli str. K-12 substr. DH10B RNA polymerase factor sigma-32 YP_001732295.1 3695697 R 316385 CDS YP_001732296.1 170082976 6060758 complement(3696796..3697854) 1 NC_010473.1 putative ABC transporter, membrane protein; cell division protein FtsX 3697854 ftsX 6060758 ftsX Escherichia coli str. K-12 substr. DH10B cell division protein FtsX YP_001732296.1 3696796 R 316385 CDS YP_001732297.1 170082977 6060772 complement(3697847..3698515) 1 NC_010473.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 3698515 ftsE 6060772 ftsE Escherichia coli str. K-12 substr. DH10B cell division protein FtsE YP_001732297.1 3697847 R 316385 CDS YP_001732298.1 170082978 6061689 complement(3698518..3700011) 1 NC_010473.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 3700011 ftsY 6061689 ftsY Escherichia coli str. K-12 substr. DH10B cell division protein FtsY YP_001732298.1 3698518 R 316385 CDS YP_001732299.1 170082979 6061676 3700161..3700757 1 NC_010473.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3700757 rsmD 6061676 rsmD Escherichia coli str. K-12 substr. DH10B 16S rRNA m(2)G966-methyltransferase YP_001732299.1 3700161 D 316385 CDS YP_001732300.1 170082980 6061651 3700747..3701016 1 NC_010473.1 hypothetical protein 3701016 yhhL 6061651 yhhL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732300.1 3700747 D 316385 CDS YP_001732301.1 170082981 6061737 complement(3701019..3701378) 1 NC_010473.1 hypothetical protein 3701378 yhhM 6061737 yhhM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732301.1 3701019 R 316385 CDS YP_001732302.1 170082982 6060862 3701519..3702145 1 NC_010473.1 inner membrane protein 3702145 yhhN 6060862 yhhN Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732302.1 3701519 D 316385 CDS YP_001732303.1 170082983 6060788 3702219..3704417 1 NC_010473.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3704417 zntA 6060788 zntA Escherichia coli str. K-12 substr. DH10B zinc/cadmium/mercury/lead-transporting ATPase YP_001732303.1 3702219 D 316385 CDS YP_001732304.1 170082984 6061870 complement(3704519..3704764) 1 NC_010473.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 3704764 sirA 6061870 sirA Escherichia coli str. K-12 substr. DH10B sulfur transfer protein SirA YP_001732304.1 3704519 R 316385 CDS YP_001732305.1 170082985 6060880 3704985..3705650 1 NC_010473.1 hypothetical protein 3705650 yhhQ 6060880 yhhQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732305.1 3704985 D 316385 CDS YP_001732306.1 170082986 6060782 3705723..3706280 1 NC_010473.1 hypothetical protein 3706280 dcrB 6060782 dcrB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732306.1 3705723 D 316385 CDS YP_001732307.1 170082987 6060565 complement(3706284..3707501) 1 NC_010473.1 major facilitator superfamily transporter 3707501 yhhS 6060565 yhhS Escherichia coli str. K-12 substr. DH10B major facilitator superfamily transporter YP_001732307.1 3706284 R 316385 CDS YP_001732308.1 170082988 6061502 3707633..3708682 1 NC_010473.1 inner membrane protein 3708682 yhhT 6061502 yhhT Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732308.1 3707633 D 316385 CDS YP_001732309.1 170082989 6061501 3708737..3709324 1 NC_010473.1 holo-(acyl carrier protein) synthase 2 3709324 acpT 6061501 acpT Escherichia coli str. K-12 substr. DH10B holo-(acyl carrier protein) synthase 2 YP_001732309.1 3708737 D 316385 CDS YP_001732310.1 170082990 6061813 3709435..3711009 1 NC_010473.1 nickel ABC transporter periplasmic substrate-binding proteinsuperfamily 3711009 nikA 6061813 nikA Escherichia coli str. K-12 substr. DH10B nickel ABC transporter periplasmic substrate-binding proteinsuperfamily YP_001732310.1 3709435 D 316385 CDS YP_001732311.1 170082991 6060831 3711009..3711953 1 NC_010473.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3711953 nikB 6060831 nikB Escherichia coli str. K-12 substr. DH10B nickel transporter permease NikB YP_001732311.1 3711009 D 316385 CDS YP_001732312.1 170082992 6060878 3711950..3712783 1 NC_010473.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3712783 nikC 6060878 nikC Escherichia coli str. K-12 substr. DH10B nickel transporter permease NikC YP_001732312.1 3711950 D 316385 CDS YP_001732313.1 170082993 6061915 3712783..3713547 1 NC_010473.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3713547 nikD 6061915 nikD Escherichia coli str. K-12 substr. DH10B nickel transporter ATP-binding protein NikD YP_001732313.1 3712783 D 316385 CDS YP_001732314.1 170082994 6060953 3713544..3714350 1 NC_010473.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3714350 nikE 6060953 nikE Escherichia coli str. K-12 substr. DH10B nickel transporter ATP-binding protein NikE YP_001732314.1 3713544 D 316385 CDS YP_001732315.1 170082995 6061845 3714356..3714757 1 NC_010473.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3714757 nikR 6061845 nikR Escherichia coli str. K-12 substr. DH10B nickel responsive regulator YP_001732315.1 3714356 D 316385 CDS YP_001732316.1 170082996 6059476 3714960..3719195 1 NC_010473.1 rhsB element core protein RshB 3719195 rhsB 6059476 rhsB Escherichia coli str. K-12 substr. DH10B rhsB element core protein RshB YP_001732316.1 3714960 D 316385 CDS YP_001732317.1 170082997 6059504 3719167..3719550 1 NC_010473.1 hypothetical protein 3719550 yhhH 6059504 yhhH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732317.1 3719167 D 316385 CDS YP_001732318.1 170082998 6059516 3720146..3721282 1 NC_010473.1 transposase 3721282 yhhI 6059516 yhhI Escherichia coli str. K-12 substr. DH10B transposase YP_001732318.1 3720146 D 316385 CDS YP_001732319.1 170082999 6059342 complement(3721447..3722571) 1 NC_010473.1 ABC transporter membrane protein 3722571 yhhJ 6059342 yhhJ Escherichia coli str. K-12 substr. DH10B ABC transporter membrane protein YP_001732319.1 3721447 R 316385 CDS YP_001732320.1 170083000 6059322 complement(3722571..3725306) 1 NC_010473.1 fused ribosome-associated ATPase: ATP-binding protein; ATP-binding protein; membrane protein 3725306 rbbA 6059322 rbbA Escherichia coli str. K-12 substr. DH10B fused ribosome-associated ATPase: ATP-binding protein; ATP-binding protein; membrane protein YP_001732320.1 3722571 R 316385 CDS YP_001732321.1 170083001 6059319 complement(3726736..3728358) 1 NC_010473.1 hypothetical protein 3728358 yhiJ 6059319 yhiJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732321.1 3726736 R 316385 CDS YP_001732322.1 170083002 6060646 3730609..3731661 1 NC_010473.1 inner membrane protein 3731661 yhiM 6060646 yhiM Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732322.1 3730609 D 316385 CDS YP_001732323.1 170083003 6059275 complement(3731976..3733178) 1 NC_010473.1 oxidoreductase 3733178 yhiN 6059275 yhiN Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001732323.1 3731976 R 316385 CDS YP_001732324.1 170083004 6059276 3733410..3734909 1 NC_010473.1 phosphate transporter, low-affinity 3734909 pitA 6059276 pitA Escherichia coli str. K-12 substr. DH10B phosphate transporter, low-affinity YP_001732324.1 3733410 D 316385 CDS YP_001732325.1 170083005 6059291 complement(3735153..3735488) 1 NC_010473.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 3735488 uspB 6059291 uspB Escherichia coli str. K-12 substr. DH10B universal stress protein UspB YP_001732325.1 3735153 R 316385 CDS YP_001732326.1 170083006 6059258 3735879..3736313 1 NC_010473.1 universal stress global response regulator 3736313 uspA 6059258 uspA Escherichia coli str. K-12 substr. DH10B universal stress global response regulator YP_001732326.1 3735879 D 316385 CDS YP_001732327.1 170083007 6059253 3736630..3738099 1 NC_010473.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3738099 yhiP 6059253 yhiP Escherichia coli str. K-12 substr. DH10B inner membrane transporter YhiP YP_001732327.1 3736630 D 316385 CDS YP_001732328.1 170083008 6059194 complement(3738148..3738900) 1 NC_010473.1 predicted SAM-dependent methyltransferase; putative methyltransferase 3738900 yhiQ 6059194 yhiQ Escherichia coli str. K-12 substr. DH10B putative methyltransferase YP_001732328.1 3738148 R 316385 CDS YP_001732329.1 170083009 6061226 complement(3738908..3740950) 1 NC_010473.1 oligopeptidase A 3740950 prlC 6061226 prlC Escherichia coli str. K-12 substr. DH10B oligopeptidase A YP_001732329.1 3738908 R 316385 CDS YP_001732330.1 170083010 6058314 3741153..3741995 1 NC_010473.1 DNA (exogenous) processing protein 3741995 yhiR 6058314 yhiR Escherichia coli str. K-12 substr. DH10B DNA (exogenous) processing protein YP_001732330.1 3741153 D 316385 CDS YP_001732331.1 170083011 6058494 3742067..3743419 1 NC_010473.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3743419 gor 6058494 gor Escherichia coli str. K-12 substr. DH10B glutathione reductase YP_001732331.1 3742067 D 316385 CDS YP_001732332.1 170083012 6058423 3744296..3744649 1 NC_010473.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3744649 arsR 6058423 arsR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor ArsR YP_001732332.1 3744296 D 316385 CDS YP_001732333.1 170083013 6062297 3744703..3745992 1 NC_010473.1 arsenite/antimonite transporter 3745992 arsB 6062297 arsB Escherichia coli str. K-12 substr. DH10B arsenite/antimonite transporter YP_001732333.1 3744703 D 316385 CDS YP_001732334.1 170083014 6058451 3746005..3746430 1 NC_010473.1 arsenate reductase 3746430 arsC 6058451 arsC Escherichia coli str. K-12 substr. DH10B arsenate reductase YP_001732334.1 3746005 D 316385 CDS YP_001732335.1 170083015 6058123 3747059..3747841 1 NC_010473.1 hypothetical protein 3747841 yhiS 6058123 yhiS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732335.1 3747059 D 316385 CDS YP_001732336.1 170083016 6058356 complement(3747950..3748966) 1 NC_010473.1 IS5 transposase and trans-activator 3748966 insH-11 6058356 insH-11 Escherichia coli str. K-12 substr. DH10B IS5 transposase and trans-activator YP_001732336.1 3747950 R 316385 CDS YP_001732337.1 170083017 6062268 3749729..3750295 1 NC_010473.1 outer membrane lipoprotein 3750295 slp 6062268 slp Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein YP_001732337.1 3749729 D 316385 CDS YP_001732338.1 170083018 6059229 3750451..3750981 1 NC_010473.1 DNA-binding ranscriptional regulator 3750981 yhiF 6059229 yhiF Escherichia coli str. K-12 substr. DH10B DNA-binding ranscriptional regulator YP_001732338.1 3750451 D 316385 CDS YP_001732339.1 170083019 6059140 complement(3751023..3751670) 1 NC_010473.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase 3751670 yhiD 6059140 yhiD Escherichia coli str. K-12 substr. DH10B putative Mg(2+) transport ATPase YP_001732339.1 3751023 R 316385 CDS YP_001732340.1 170083020 6059135 complement(3751734..3752060) 1 NC_010473.1 acid-resistance protein 3752060 hdeB 6059135 hdeB Escherichia coli str. K-12 substr. DH10B acid-resistance protein YP_001732340.1 3751734 R 316385 CDS YP_001732341.1 170083021 6059193 complement(3752176..3752508) 1 NC_010473.1 inactive form; acid-resistance protein 3752508 hdeA 6059193 hdeA Escherichia coli str. K-12 substr. DH10B acid-resistance protein YP_001732341.1 3752176 R 316385 CDS YP_001732342.1 170083022 6059201 3752763..3753335 1 NC_010473.1 acid-resistance membrane protein 3753335 hdeD 6059201 hdeD Escherichia coli str. K-12 substr. DH10B acid-resistance membrane protein YP_001732342.1 3752763 D 316385 CDS YP_001732343.1 170083023 6059166 3754134..3754661 1 NC_010473.1 acid-induced positive regulator of glutamate-dependent acid resistance 3754661 gadE 6059166 gadE Escherichia coli str. K-12 substr. DH10B acid-induced positive regulator of glutamate-dependent acid resistance YP_001732343.1 3754134 D 316385 CDS YP_001732344.1 170083024 6059151 3755000..3756157 1 NC_010473.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3756157 mdtE 6059151 mdtE Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein MdtE YP_001732344.1 3755000 D 316385 CDS YP_001732345.1 170083025 6059132 3756182..3759295 1 NC_010473.1 multidrug transporter, RpoS-dependent 3759295 mdtF 6059132 mdtF Escherichia coli str. K-12 substr. DH10B multidrug transporter, RpoS-dependent YP_001732345.1 3756182 D 316385 CDS YP_001732346.1 170083026 6059159 complement(3759658..3760386) 1 NC_010473.1 DNA-binding transcriptional activator 3760386 gadW 6059159 gadW Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator YP_001732346.1 3759658 R 316385 CDS YP_001732347.1 170083027 6058913 complement(3760754..3761578) 1 NC_010473.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3761578 gadX 6058913 gadX Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator GadX YP_001732347.1 3760754 R 316385 CDS YP_001732348.1 170083028 6059024 complement(3761948..3763348) 1 NC_010473.1 glutamate decarboxylase 3763348 gadA 6059024 gadA Escherichia coli str. K-12 substr. DH10B glutamate decarboxylase YP_001732348.1 3761948 R 316385 CDS YP_001732349.1 170083029 6059089 complement(3763559..3764956) 1 NC_010473.1 cytochrome C peroxidase 3764956 yhjA 6059089 yhjA Escherichia coli str. K-12 substr. DH10B cytochrome C peroxidase YP_001732349.1 3763559 R 316385 CDS YP_001732350.1 170083030 6059091 3765360..3767009 1 NC_010473.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3767009 treF 6059091 treF Escherichia coli str. K-12 substr. DH10B trehalase YP_001732350.1 3765360 D 316385 CDS YP_001732351.1 170083031 6058970 complement(3767060..3767662) 1 NC_010473.1 DNA-binding response regulator in two-component regulatory system 3767662 yhjB 6058970 yhjB Escherichia coli str. K-12 substr. DH10B DNA-binding response regulator in two-component regulatory system YP_001732351.1 3767060 R 316385 CDS YP_001732352.1 170083032 6059028 3768110..3769081 1 NC_010473.1 DNA-binding transcriptional regulator 3769081 yhjC 6059028 yhjC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732352.1 3768110 D 316385 CDS YP_001732353.1 170083033 6059013 3769130..3770143 1 NC_010473.1 inner membrane protein 3770143 yhjD 6059013 yhjD Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732353.1 3769130 D 316385 CDS YP_001732354.1 170083034 6059002 3770554..3771876 1 NC_010473.1 transporter 3771876 yhjE 6059002 yhjE Escherichia coli str. K-12 substr. DH10B transporter YP_001732354.1 3770554 D 316385 CDS YP_001732355.1 170083035 6058924 complement(3772058..3774133) 1 NC_010473.1 outer membrane biogenesis protein 3774133 yhjG 6058924 yhjG Escherichia coli str. K-12 substr. DH10B outer membrane biogenesis protein YP_001732355.1 3772058 R 316385 CDS YP_001732356.1 170083036 6061340 complement(3774188..3774955) 1 NC_010473.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 3774955 yhjH 6061340 yhjH Escherichia coli str. K-12 substr. DH10B EAL domain-containing protein YP_001732356.1 3774188 R 316385 CDS YP_001732357.1 170083037 6058947 3775187..3776116 1 NC_010473.1 ketodeoxygluconokinase 3776116 kdgK 6058947 kdgK Escherichia coli str. K-12 substr. DH10B ketodeoxygluconokinase YP_001732357.1 3775187 D 316385 CDS YP_001732358.1 170083038 6058940 complement(3776212..3777708) 1 NC_010473.1 zinc-dependent peptidase 3777708 yhjJ 6058940 yhjJ Escherichia coli str. K-12 substr. DH10B zinc-dependent peptidase YP_001732358.1 3776212 R 316385 CDS YP_001732359.1 170083039 6058876 complement(3779398..3781347) 1 NC_010473.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase 3781347 yhjK 6058876 yhjK Escherichia coli str. K-12 substr. DH10B putative phosphodiesterase YP_001732359.1 3779398 R 316385 CDS YP_001732360.1 170083040 6058880 complement(3781468..3784941) 1 NC_010473.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 3784941 bcsC 6058880 bcsC Escherichia coli str. K-12 substr. DH10B cellulose synthase subunit BcsC YP_001732360.1 3781468 R 316385 CDS YP_001732361.1 170083041 6058894 complement(3784923..3786029) 1 NC_010473.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 3786029 bcsZ 6058894 bcsZ Escherichia coli str. K-12 substr. DH10B endo-1,4-D-glucanase YP_001732361.1 3784923 R 316385 CDS YP_001732362.1 170083042 6058936 complement(3786036..3788375) 1 NC_010473.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 3788375 bcsB 6058936 bcsB Escherichia coli str. K-12 substr. DH10B cellulose synthase regulator protein YP_001732362.1 3786036 R 316385 CDS YP_001732363.1 170083043 6058813 complement(3788386..3791004) 1 NC_010473.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 3791004 bcsA 6058813 bcsA Escherichia coli str. K-12 substr. DH10B cellulose synthase catalytic subunit YP_001732363.1 3788386 R 316385 CDS YP_001732364.1 170083044 6059447 complement(3791765..3791953) 1 NC_010473.1 hypothetical protein 3791953 yhjR 6059447 yhjR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732364.1 3791765 R 316385 CDS YP_001732365.1 170083045 6058838 3793794..3793985 1 NC_010473.1 hypothetical protein 3793985 bcsF 6058838 bcsF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732365.1 3793794 D 316385 CDS YP_001732366.1 170083046 6058866 3793982..3795661 1 NC_010473.1 inner membrane protein 3795661 bcsG 6058866 bcsG Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732366.1 3793982 D 316385 CDS YP_001732367.1 170083047 6058730 complement(3795748..3795855) 1 NC_010473.1 toxic polypeptide, small 3795855 ldrD 6058730 ldrD Escherichia coli str. K-12 substr. DH10B toxic polypeptide, small YP_001732367.1 3795748 R 316385 CDS YP_001732368.1 170083048 6058867 3796331..3797602 1 NC_010473.1 transporter 3797602 yhjV 6058867 yhjV Escherichia coli str. K-12 substr. DH10B transporter YP_001732368.1 3796331 D 316385 CDS YP_001732369.1 170083049 6058713 complement(3797632..3798636) 1 NC_010473.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 3798636 dppF 6058713 dppF Escherichia coli str. K-12 substr. DH10B dipeptide transporter ATP-binding subunit YP_001732369.1 3797632 R 316385 CDS YP_001732370.1 170083050 6058811 complement(3798633..3799616) 1 NC_010473.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 3799616 dppD 6058811 dppD Escherichia coli str. K-12 substr. DH10B dipeptide transporter ATP-binding subunit YP_001732370.1 3798633 R 316385 CDS YP_001732371.1 170083051 6058635 complement(3799627..3800529) 1 NC_010473.1 dipeptide transporter 3800529 dppC 6058635 dppC Escherichia coli str. K-12 substr. DH10B dipeptide transporter YP_001732371.1 3799627 R 316385 CDS YP_001732372.1 170083052 6060743 complement(3800539..3801558) 1 NC_010473.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 3801558 dppB 6060743 dppB Escherichia coli str. K-12 substr. DH10B dipeptide transporter permease DppB YP_001732372.1 3800539 R 316385 CDS YP_001732373.1 170083053 6058698 complement(3801866..3803473) 1 NC_010473.1 peptide ABC transporter periplasmic substrate-binding protein 3803473 dppA 6058698 dppA Escherichia coli str. K-12 substr. DH10B peptide ABC transporter periplasmic substrate-binding protein YP_001732373.1 3801866 R 316385 CDS YP_001732374.1 170083054 6058810 complement(3804384..3806075) 1 NC_010473.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 3806075 eptB 6058810 eptB Escherichia coli str. K-12 substr. DH10B phosphoethanolamine transferase YP_001732374.1 3804384 R 316385 CDS YP_001732375.1 170083055 6058565 complement(3806399..3807607) 1 NC_010473.1 transporter 3807607 yhjX 6058565 yhjX Escherichia coli str. K-12 substr. DH10B transporter YP_001732375.1 3806399 R 316385 CDS YP_001732376.1 170083056 6058487 complement(3807836..3808534) 1 NC_010473.1 hypothetical protein 3808534 yhjY 6058487 yhjY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732376.1 3807836 R 316385 CDS YP_001732377.1 170083057 6058528 3808692..3809255 1 NC_010473.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 3809255 tag 6058528 tag Escherichia coli str. K-12 substr. DH10B 3-methyladenine DNA glycosylase YP_001732377.1 3808692 D 316385 CDS YP_001732378.1 170083058 6060166 3809252..3809692 1 NC_010473.1 hypothetical protein 3809692 yiaC 6060166 yiaC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732378.1 3809252 D 316385 CDS YP_001732379.1 170083059 6058125 complement(3809661..3811940) 1 NC_010473.1 biotin sulfoxide reductase 3811940 bisC 6058125 bisC Escherichia coli str. K-12 substr. DH10B biotin sulfoxide reductase YP_001732379.1 3809661 R 316385 CDS YP_001732380.1 170083060 6058362 3812147..3812806 1 NC_010473.1 putative outer membrane lipoprotein 3812806 yiaD 6058362 yiaD Escherichia coli str. K-12 substr. DH10B putative outer membrane lipoprotein YP_001732380.1 3812147 D 316385 CDS YP_001732381.1 170083061 6058427 3812910..3813884 1 NC_010473.1 2-keto-D-gluconate reductase (glyoxalate reductase) (2-ketoaldonate reductase) 3813884 tiaE 6058427 tiaE Escherichia coli str. K-12 substr. DH10B 2-keto-D-gluconate reductase (glyoxalate reductase) (2-ketoaldonate reductase) YP_001732381.1 3812910 D 316385 CDS YP_001732382.1 170083062 6058102 complement(3813934..3814644) 1 NC_010473.1 hypothetical protein 3814644 yiaF 6058102 yiaF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732382.1 3813934 R 316385 CDS YP_001732383.1 170083063 6058377 3815078..3815368 1 NC_010473.1 putative transcriptional regulator 3815368 yiaG 6058377 yiaG Escherichia coli str. K-12 substr. DH10B putative transcriptional regulator YP_001732383.1 3815078 D 316385 CDS YP_001732384.1 170083064 6058592 3815649..3815861 1 NC_010473.1 major cold shock protein 3815861 cspA 6058592 cspA Escherichia coli str. K-12 substr. DH10B major cold shock protein YP_001732384.1 3815649 D 316385 CDS YP_001732385.1 170083065 6058336 complement(3816048..3816200) 1 NC_010473.1 small toxic polypeptide 3816200 hokA 6058336 hokA Escherichia coli str. K-12 substr. DH10B small toxic polypeptide YP_001732385.1 3816048 R 316385 CDS YP_001732386.1 170083066 6058292 3816280..3816801 1 NC_010473.1 IS150 protein InsA 3816801 insJ 6058292 insJ Escherichia coli str. K-12 substr. DH10B IS150 protein InsA YP_001732386.1 3816280 D 316385 CDS YP_001732387.1 170083067 6058414 3816798..3817649 1 NC_010473.1 IS150 protein InsB 3817649 insK 6058414 insK Escherichia coli str. K-12 substr. DH10B IS150 protein InsB YP_001732387.1 3816798 D 316385 CDS YP_001732388.1 170083068 6058311 complement(3817928..3819997) 1 NC_010473.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 3819997 glyS 6058311 glyS Escherichia coli str. K-12 substr. DH10B glycyl-tRNA synthetase subunit beta YP_001732388.1 3817928 R 316385 CDS YP_001732389.1 170083069 6058569 complement(3821013..3821312) 1 NC_010473.1 hypothetical protein 3821312 ysaB 6058569 ysaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732389.1 3821013 R 316385 CDS YP_001732390.1 170083070 6058351 3821487..3822482 1 NC_010473.1 inner membrane protein 3822482 yiaH 6058351 yiaH Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732390.1 3821487 D 316385 CDS YP_001732391.1 170083071 6058261 complement(3822524..3822961) 1 NC_010473.1 hypothetical protein 3822961 yiaA 6058261 yiaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732391.1 3822524 R 316385 CDS YP_001732392.1 170083072 6058535 complement(3823007..3823348) 1 NC_010473.1 hypothetical protein 3823348 yiaB 6058535 yiaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732392.1 3823007 R 316385 CDS YP_001732393.1 170083073 6058551 complement(3823517..3824971) 1 NC_010473.1 xylulokinase 3824971 xylB 6058551 xylB Escherichia coli str. K-12 substr. DH10B xylulokinase YP_001732393.1 3823517 R 316385 CDS YP_001732394.1 170083074 6062400 complement(3825043..3826365) 1 NC_010473.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 3826365 xylA 6062400 xylA Escherichia coli str. K-12 substr. DH10B xylose isomerase YP_001732394.1 3825043 R 316385 CDS YP_001732395.1 170083075 6059130 3826731..3827723 1 NC_010473.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3827723 xylF 6059130 xylF Escherichia coli str. K-12 substr. DH10B D-xylose transporter subunit XylF YP_001732395.1 3826731 D 316385 CDS YP_001732396.1 170083076 6059469 3827801..3829342 1 NC_010473.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3829342 xylG 6059469 xylG Escherichia coli str. K-12 substr. DH10B xylose transporter ATP-binding subunit YP_001732396.1 3827801 D 316385 CDS YP_001732397.1 170083077 6058185 3829320..3830501 1 NC_010473.1 D-xylose ABC transporter membrane protein 3830501 xylH 6058185 xylH Escherichia coli str. K-12 substr. DH10B D-xylose ABC transporter membrane protein YP_001732397.1 3829320 D 316385 CDS YP_001732398.1 170083078 6059460 3830579..3831757 1 NC_010473.1 DNA-binding transcriptional activator, xylose-binding 3831757 xylR 6059460 xylR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator, xylose-binding YP_001732398.1 3830579 D 316385 CDS YP_001732399.1 170083079 6059451 complement(3831953..3832777) 1 NC_010473.1 hypothetical protein 3832777 bax 6059451 bax Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732399.1 3831953 R 316385 CDS YP_001732400.1 170083080 6059446 3833097..3835127 1 NC_010473.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3835127 malS 6059446 malS Escherichia coli str. K-12 substr. DH10B periplasmic alpha-amylase YP_001732400.1 3833097 D 316385 CDS YP_001732401.1 170083081 6058540 3835305..3836558 1 NC_010473.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3836558 avtA 6058540 avtA Escherichia coli str. K-12 substr. DH10B valine--pyruvate transaminase YP_001732401.1 3835305 D 316385 CDS YP_001732402.1 170083082 6059441 complement(3836709..3837182) 1 NC_010473.1 hydrogenase, 4Fe-4S ferredoxin-type component 3837182 ysaA 6059441 ysaA Escherichia coli str. K-12 substr. DH10B hydrogenase, 4Fe-4S ferredoxin-type component YP_001732402.1 3836709 R 316385 CDS YP_001732403.1 170083083 6059430 complement(3837284..3838132) 1 NC_010473.1 DNA-binding transcriptional repressor 3838132 yiaJ 6059430 yiaJ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor YP_001732403.1 3837284 R 316385 CDS YP_001732404.1 170083084 6058124 3838333..3839331 1 NC_010473.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3839331 yiaK 6058124 yiaK Escherichia coli str. K-12 substr. DH10B 2,3-diketo-L-gulonate reductase YP_001732404.1 3838333 D 316385 CDS YP_001732405.1 170083085 6059420 3839343..3839810 1 NC_010473.1 hypothetical protein 3839810 yiaL 6059420 yiaL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732405.1 3839343 D 316385 CDS YP_001732406.1 170083086 6059411 3839928..3840401 1 NC_010473.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease 3840401 yiaM 6059411 yiaM Escherichia coli str. K-12 substr. DH10B 2,3-diketo-L-gulonate TRAP transporter small permease YP_001732406.1 3839928 D 316385 CDS YP_001732407.1 170083087 6059492 3840404..3841681 1 NC_010473.1 transporter 3841681 yiaN 6059492 yiaN Escherichia coli str. K-12 substr. DH10B transporter YP_001732407.1 3840404 D 316385 CDS YP_001732408.1 170083088 6059417 3841694..3842680 1 NC_010473.1 transporter 3842680 yiaO 6059417 yiaO Escherichia coli str. K-12 substr. DH10B transporter YP_001732408.1 3841694 D 316385 CDS YP_001732409.1 170083089 6059390 3842684..3844180 1 NC_010473.1 L-xylulose kinase 3844180 lyxK 6059390 lyxK Escherichia coli str. K-12 substr. DH10B L-xylulose kinase YP_001732409.1 3842684 D 316385 CDS YP_001732410.1 170083090 6058426 3844177..3844839 1 NC_010473.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3844839 sgbH 6058426 sgbH Escherichia coli str. K-12 substr. DH10B 3-keto-L-gulonate-6-phosphate decarboxylase YP_001732410.1 3844177 D 316385 CDS YP_001732411.1 170083091 6058239 3844832..3845692 1 NC_010473.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 3845692 sgbU 6058239 sgbU Escherichia coli str. K-12 substr. DH10B putative L-xylulose 5-phosphate 3-epimerase YP_001732411.1 3844832 D 316385 CDS YP_001732412.1 170083092 6062156 3845686..3846381 1 NC_010473.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3846381 sgbE 6062156 sgbE Escherichia coli str. K-12 substr. DH10B L-ribulose-5-phosphate 4-epimerase YP_001732412.1 3845686 D 316385 CDS YP_001732413.1 170083093 6059588 complement(3846728..3847468) 1 NC_010473.1 hypothetical protein 3847468 yiaT 6059588 yiaT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732413.1 3846728 R 316385 CDS YP_001732414.1 170083094 6059616 3847592..3848566 1 NC_010473.1 DNA-binding transcriptional regulator 3848566 yiaU 6059616 yiaU Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732414.1 3847592 D 316385 CDS YP_001732415.1 170083095 6059641 complement(3848563..3849699) 1 NC_010473.1 membrane fusion protein (MFP) component of efflux pump, signal anchor 3849699 yiaV 6059641 yiaV Escherichia coli str. K-12 substr. DH10B membrane fusion protein (MFP) component of efflux pump, signal anchor YP_001732415.1 3848563 R 316385 CDS YP_001732416.1 170083096 6059610 complement(3849705..3850028) 1 NC_010473.1 inner membrane protein 3850028 yiaW 6059610 yiaW Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732416.1 3849705 R 316385 CDS YP_001732417.1 170083097 6059637 complement(3850573..3852111) 1 NC_010473.1 aldehyde dehydrogenase B 3852111 aldB 6059637 aldB Escherichia coli str. K-12 substr. DH10B aldehyde dehydrogenase B YP_001732417.1 3850573 R 316385 CDS YP_001732418.1 170083098 6059705 complement(3852276..3853427) 1 NC_010473.1 putative alcohol dehydrogenase 3853427 yiaY 6059705 yiaY Escherichia coli str. K-12 substr. DH10B putative alcohol dehydrogenase YP_001732418.1 3852276 R 316385 CDS YP_001732419.1 170083099 6058483 complement(3853617..3855461) 1 NC_010473.1 selenocysteinyl-tRNA-specific translation factor 3855461 selB 6058483 selB Escherichia coli str. K-12 substr. DH10B selenocysteinyl-tRNA-specific translation factor YP_001732419.1 3853617 R 316385 CDS YP_001732420.1 170083100 6058408 complement(3856947..3857555) 1 NC_010473.1 putative glutathione S-transferase 3857555 yibF 6058408 yibF Escherichia coli str. K-12 substr. DH10B putative glutathione S-transferase YP_001732420.1 3856947 R 316385 CDS YP_001732421.1 170083101 6058412 3861937..3862779 1 NC_010473.1 hypothetical protein 3862779 yibA 6058412 yibA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732421.1 3861937 D 316385 CDS YP_001732422.1 170083102 6058264 3862821..3863522 1 NC_010473.1 Rhs-family protein 3863522 yibJ 6058264 yibJ Escherichia coli str. K-12 substr. DH10B Rhs-family protein YP_001732422.1 3862821 D 316385 CDS YP_001732423.1 170083103 6059740 3863777..3864238 1 NC_010473.1 hypothetical protein 3864238 yibG 6059740 yibG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732423.1 3863777 D 316385 CDS YP_001732424.1 170083104 6058110 complement(3865843..3866979) 1 NC_010473.1 hypothetical protein 3866979 yibH 6058110 yibH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732424.1 3865843 R 316385 CDS YP_001732425.1 170083105 6058318 complement(3866982..3867344) 1 NC_010473.1 inner membrane protein 3867344 yibI 6058318 yibI Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732425.1 3866982 R 316385 CDS YP_001732426.1 170083106 6058279 3867881..3869794 1 NC_010473.1 fused mannitol-specific PTS enzymes: IIA components; IIB components; IIC components 3869794 mtlA 6058279 mtlA Escherichia coli str. K-12 substr. DH10B fused mannitol-specific PTS enzymes: IIA components; IIB components; IIC components YP_001732426.1 3867881 D 316385 CDS YP_001732427.1 170083107 6058514 3870024..3871172 1 NC_010473.1 mannitol-1-phosphate 5-dehydrogenase 3871172 mtlD 6058514 mtlD Escherichia coli str. K-12 substr. DH10B mannitol-1-phosphate 5-dehydrogenase YP_001732427.1 3870024 D 316385 CDS YP_001732428.1 170083108 6058193 3871172..3871759 1 NC_010473.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 3871759 mtlR 6058193 mtlR Escherichia coli str. K-12 substr. DH10B mannitol repressor protein YP_001732428.1 3871172 D 316385 CDS YP_001732429.1 170083109 6058135 complement(3871771..3871980) 1 NC_010473.1 hypothetical protein 3871980 yibT 6058135 yibT Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732429.1 3871771 R 316385 CDS YP_001732430.1 170083110 6058211 3872265..3872627 1 NC_010473.1 hypothetical protein 3872627 yibL 6058211 yibL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732430.1 3872265 D 316385 CDS YP_001732431.1 170083111 6058223 3872999..3874654 1 NC_010473.1 L-lactate permease 3874654 lldP 6058223 lldP Escherichia coli str. K-12 substr. DH10B L-lactate permease YP_001732431.1 3872999 D 316385 CDS YP_001732432.1 170083112 6058131 3874654..3875430 1 NC_010473.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3875430 lldR 6058131 lldR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor LldR YP_001732432.1 3874654 D 316385 CDS YP_001732433.1 170083113 6058555 3875427..3876617 1 NC_010473.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3876617 lldD 6058555 lldD Escherichia coli str. K-12 substr. DH10B L-lactate dehydrogenase YP_001732433.1 3875427 D 316385 CDS YP_001732434.1 170083114 6058477 3876815..3877288 1 NC_010473.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA/rRNA methyltransferase YibK 3877288 yibK 6058477 yibK Escherichia coli str. K-12 substr. DH10B putative tRNA/rRNA methyltransferase YibK YP_001732434.1 3876815 D 316385 CDS YP_001732435.1 170083115 6058545 complement(3877341..3878162) 1 NC_010473.1 catalyzes the O-acetylation of serine; serine acetyltransferase 3878162 cysE 6058545 cysE Escherichia coli str. K-12 substr. DH10B serine acetyltransferase YP_001732435.1 3877341 R 316385 CDS YP_001732436.1 170083116 6058267 complement(3878242..3879261) 1 NC_010473.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3879261 gpsA 6058267 gpsA Escherichia coli str. K-12 substr. DH10B NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001732436.1 3878242 R 316385 CDS YP_001732437.1 170083117 6058410 complement(3879261..3879728) 1 NC_010473.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 3879728 secB 6058410 secB Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit SecB YP_001732437.1 3879261 R 316385 CDS YP_001732438.1 170083118 6058583 complement(3879791..3880042) 1 NC_010473.1 glutaredoxin 3 3880042 grxC 6058583 grxC Escherichia coli str. K-12 substr. DH10B glutaredoxin 3 YP_001732438.1 3879791 R 316385 CDS YP_001732439.1 170083119 6059817 complement(3880184..3880615) 1 NC_010473.1 rhodanese-related sulfurtransferase 3880615 yibN 6059817 yibN Escherichia coli str. K-12 substr. DH10B rhodanese-related sulfurtransferase YP_001732439.1 3880184 R 316385 CDS YP_001732440.1 170083120 6059831 3880860..3882404 1 NC_010473.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3882404 gpmI 6059831 gpmI Escherichia coli str. K-12 substr. DH10B phosphoglyceromutase YP_001732440.1 3880860 D 316385 CDS YP_001732441.2 228937032 6058310 3882414..3883697 1 NC_010473.1 hypothetical protein 3883697 envC 6058310 envC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732441.2 3882414 D 316385 CDS YP_001732442.1 170083122 6059874 3883701..3884660 1 NC_010473.1 polysaccharide deacetylase 3884660 yibQ 6059874 yibQ Escherichia coli str. K-12 substr. DH10B polysaccharide deacetylase YP_001732442.1 3883701 D 316385 CDS YP_001732443.1 170083123 6059882 complement(3884647..3885681) 1 NC_010473.1 putative glycosyl transferase 3885681 yibD 6059882 yibD Escherichia coli str. K-12 substr. DH10B putative glycosyl transferase YP_001732443.1 3884647 R 316385 CDS YP_001732444.1 170083124 6059902 complement(3885920..3886945) 1 NC_010473.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 3886945 tdh 6059902 tdh Escherichia coli str. K-12 substr. DH10B L-threonine 3-dehydrogenase YP_001732444.1 3885920 R 316385 CDS YP_001732445.1 170083125 6059968 complement(3886955..3888151) 1 NC_010473.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 3888151 kbl 6059968 kbl Escherichia coli str. K-12 substr. DH10B 2-amino-3-ketobutyrate coenzyme A ligase YP_001732445.1 3886955 R 316385 CDS YP_001732446.1 170083126 6058444 complement(3888426..3889283) 1 NC_010473.1 hypothetical protein 3889283 htrL 6058444 htrL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732446.1 3888426 R 316385 CDS YP_001732447.1 170083127 6058213 3889587..3890519 1 NC_010473.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 3890519 rfaD 6058213 rfaD Escherichia coli str. K-12 substr. DH10B ADP-L-glycero-D-manno-heptose-6-epimerase YP_001732447.1 3889587 D 316385 CDS YP_001732448.1 170083128 6058611 3890529..3891575 1 NC_010473.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 3891575 rfaF 6058611 rfaF Escherichia coli str. K-12 substr. DH10B ADP-heptose--LPS heptosyltransferase YP_001732448.1 3890529 D 316385 CDS YP_001732449.1 170083129 6058194 3891579..3892538 1 NC_010473.1 ADP-heptose--LPS heptosyltransferase 3892538 rfaC 6058194 rfaC Escherichia coli str. K-12 substr. DH10B ADP-heptose--LPS heptosyltransferase YP_001732449.1 3891579 D 316385 CDS YP_001732450.1 170083130 6058443 3892548..3893807 1 NC_010473.1 O-antigen ligase 3893807 rfaL 6058443 rfaL Escherichia coli str. K-12 substr. DH10B O-antigen ligase YP_001732450.1 3892548 D 316385 CDS YP_001732451.1 170083131 6058515 complement(3893839..3894912) 1 NC_010473.1 lipopolysaccharide core biosynthesis protein 3894912 rfaK 6058515 rfaK Escherichia coli str. K-12 substr. DH10B lipopolysaccharide core biosynthesis protein YP_001732451.1 3893839 R 316385 CDS YP_001732452.1 170083132 6058395 complement(3894945..3895796) 1 NC_010473.1 lipopolysaccharide core biosynthesis protein 3895796 rfaZ 6058395 rfaZ Escherichia coli str. K-12 substr. DH10B lipopolysaccharide core biosynthesis protein YP_001732452.1 3894945 R 316385 CDS YP_001732453.1 170083133 6058413 complement(3895867..3896565) 1 NC_010473.1 lipopolysaccharide core biosynthesis protein 3896565 rfaY 6058413 rfaY Escherichia coli str. K-12 substr. DH10B lipopolysaccharide core biosynthesis protein YP_001732453.1 3895867 R 316385 CDS YP_001732454.1 170083134 6058482 complement(3896583..3897599) 1 NC_010473.1 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase 3897599 rfaJ 6058482 rfaJ Escherichia coli str. K-12 substr. DH10B UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase YP_001732454.1 3896583 R 316385 CDS YP_001732455.1 170083135 6058501 complement(3897639..3898658) 1 NC_010473.1 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase 3898658 rfaI 6058501 rfaI Escherichia coli str. K-12 substr. DH10B UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase YP_001732455.1 3897639 R 316385 CDS YP_001732456.1 170083136 6060068 complement(3898658..3899767) 1 NC_010473.1 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase 3899767 rfaB 6060068 rfaB Escherichia coli str. K-12 substr. DH10B UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase YP_001732456.1 3898658 R 316385 CDS YP_001732457.1 170083137 6058112 complement(3899781..3900716) 1 NC_010473.1 lipopolysaccharide core biosynthesis protein 3900716 rfaS 6058112 rfaS Escherichia coli str. K-12 substr. DH10B lipopolysaccharide core biosynthesis protein YP_001732457.1 3899781 R 316385 CDS YP_001732458.1 170083138 6058388 complement(3900753..3901550) 1 NC_010473.1 kinase that phosphorylates core heptose of lipopolysaccharide 3901550 rfaP 6058388 rfaP Escherichia coli str. K-12 substr. DH10B kinase that phosphorylates core heptose of lipopolysaccharide YP_001732458.1 3900753 R 316385 CDS YP_001732459.1 170083139 6058520 complement(3901543..3902667) 1 NC_010473.1 glucosyltransferase I 3902667 rfaG 6058520 rfaG Escherichia coli str. K-12 substr. DH10B glucosyltransferase I YP_001732459.1 3901543 R 316385 CDS YP_001732460.1 170083140 6060080 complement(3902664..3903698) 1 NC_010473.1 lipopolysaccharide core biosynthesis protein 3903698 rfaQ 6060080 rfaQ Escherichia coli str. K-12 substr. DH10B lipopolysaccharide core biosynthesis protein YP_001732460.1 3902664 R 316385 CDS YP_001732461.1 170083141 6060097 3904140..3905417 1 NC_010473.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 3905417 kdtA 6060097 kdtA Escherichia coli str. K-12 substr. DH10B 3-deoxy-D-manno-octulosonic-acid transferase YP_001732461.1 3904140 D 316385 CDS YP_001732462.1 170083142 6058401 3905425..3905904 1 NC_010473.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3905904 coaD 6058401 coaD Escherichia coli str. K-12 substr. DH10B phosphopantetheine adenylyltransferase YP_001732462.1 3905425 D 316385 CDS YP_001732463.1 170083143 6058465 complement(3905943..3906752) 1 NC_010473.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 3906752 mutM 6058465 mutM Escherichia coli str. K-12 substr. DH10B formamidopyrimidine-DNA glycosylase YP_001732463.1 3905943 R 316385 CDS YP_001732464.1 170083144 6058499 complement(3906850..3907017) 1 NC_010473.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 3907017 rpmG 6058499 rpmG Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L33 YP_001732464.1 3906850 R 316385 CDS YP_001732465.1 170083145 6058417 complement(3907038..3907274) 1 NC_010473.1 required for 70S ribosome assembly; 50S ribosomal protein L28 3907274 rpmB 6058417 rpmB Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L28 YP_001732465.1 3907038 R 316385 CDS YP_001732466.1 170083146 6058532 complement(3907491..3908159) 1 NC_010473.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 3908159 radC 6058532 radC Escherichia coli str. K-12 substr. DH10B DNA repair protein RadC YP_001732466.1 3907491 R 316385 CDS YP_001732467.1 170083147 6058288 3908331..3909551 1 NC_010473.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 3909551 dfp 6058288 dfp Escherichia coli str. K-12 substr. DH10B bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001732467.1 3908331 D 316385 CDS YP_001732468.1 170083148 6058409 3909532..3909987 1 NC_010473.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3909987 dut 6058409 dut Escherichia coli str. K-12 substr. DH10B deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001732468.1 3909532 D 316385 CDS YP_001732469.1 170083149 6058287 3910094..3910690 1 NC_010473.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 3910690 slmA 6058287 slmA Escherichia coli str. K-12 substr. DH10B nucleoid occlusion protein YP_001732469.1 3910094 D 316385 CDS YP_001732470.1 170083150 6060170 complement(3910727..3911368) 1 NC_010473.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 3911368 pyrE 6060170 pyrE Escherichia coli str. K-12 substr. DH10B orotate phosphoribosyltransferase YP_001732470.1 3910727 R 316385 CDS YP_001732471.1 170083151 6060181 3912277..3913140 1 NC_010473.1 hypothetical protein 3913140 yicC 6060181 yicC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732471.1 3912277 D 316385 CDS YP_001732472.1 170083152 6058126 3913361..3914185 1 NC_010473.1 DNA-damage-inducible protein D 3914185 dinD 6058126 dinD Escherichia coli str. K-12 substr. DH10B DNA-damage-inducible protein D YP_001732472.1 3913361 D 316385 CDS YP_001732473.1 170083153 6058425 3914475..3915092 1 NC_010473.1 inner membrane protein 3915092 yicG 6058425 yicG Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732473.1 3914475 D 316385 CDS YP_001732474.1 170083154 6058350 complement(3915089..3916771) 1 NC_010473.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 3916771 ligB 6058350 ligB Escherichia coli str. K-12 substr. DH10B NAD-dependent DNA ligase LigB YP_001732474.1 3915089 R 316385 CDS YP_001732475.1 170083155 6058263 3917029..3917652 1 NC_010473.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 3917652 gmk 6058263 gmk Escherichia coli str. K-12 substr. DH10B guanylate kinase YP_001732475.1 3917029 D 316385 CDS YP_001732476.1 170083156 6058385 3917707..3917982 1 NC_010473.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 3917982 rpoZ 6058385 rpoZ Escherichia coli str. K-12 substr. DH10B DNA-directed RNA polymerase subunit omega YP_001732476.1 3917707 D 316385 CDS YP_001732477.1 170083157 6058154 3918001..3920115 1 NC_010473.1 contains a six base pair insertion resulting in addition of Gln-Asp after amino acid 84, within the overlapping hydrolase and synthetase domains, as well as a SNP causing the H257Y substitution in the regulatory domain; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 3920115 spoT 6058154 spoT Escherichia coli str. K-12 substr. DH10B bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_001732477.1 3918001 D 316385 CDS YP_001732478.1 170083158 6058601 3920122..3920811 1 NC_010473.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 3920811 spoU 6058601 spoU Escherichia coli str. K-12 substr. DH10B tRNA guanosine-2'-O-methyltransferase YP_001732478.1 3920122 D 316385 CDS YP_001732479.1 170083159 6060245 3920817..3922898 1 NC_010473.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3922898 recG 6060245 recG Escherichia coli str. K-12 substr. DH10B ATP-dependent DNA helicase RecG YP_001732479.1 3920817 D 316385 CDS YP_001732480.1 170083160 6060247 complement(3923067..3924272) 1 NC_010473.1 glutamate transporter 3924272 gltS 6060247 gltS Escherichia coli str. K-12 substr. DH10B glutamate transporter YP_001732480.1 3923067 R 316385 CDS YP_001732481.1 170083161 6060253 3924552..3925943 1 NC_010473.1 transporter 3925943 yicE 6060253 yicE Escherichia coli str. K-12 substr. DH10B transporter YP_001732481.1 3924552 D 316385 CDS YP_001732482.1 170083162 6060261 3926064..3927773 1 NC_010473.1 hypothetical protein 3927773 yicH 6060261 yicH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732482.1 3926064 D 316385 CDS YP_001732483.1 170083163 6058309 complement(3927826..3930144) 1 NC_010473.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 3930144 yicI 6058309 yicI Escherichia coli str. K-12 substr. DH10B alpha-xylosidase YP_001732483.1 3927826 R 316385 CDS YP_001732484.1 170083164 6060272 complement(3930154..3931536) 1 NC_010473.1 may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter 3931536 yicJ 6060272 yicJ Escherichia coli str. K-12 substr. DH10B putative transporter YP_001732484.1 3930154 R 316385 CDS YP_001732485.1 170083165 6058754 3932560..3933744 1 NC_010473.1 sugar efflux system 3933744 setC 6058754 setC Escherichia coli str. K-12 substr. DH10B sugar efflux system YP_001732485.1 3932560 D 316385 CDS YP_001732486.1 170083166 6058249 3933855..3934778 1 NC_010473.1 inner membrane protein 3934778 yicL 6058249 yicL Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732486.1 3933855 D 316385 CDS YP_001732487.1 170083167 6058180 complement(3934782..3935600) 1 NC_010473.1 hypothetical protein 3935600 nlpA 6058180 nlpA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732487.1 3934782 R 316385 CDS YP_001732488.1 170083168 6060315 3935822..3936115 1 NC_010473.1 hypothetical protein 3936115 yicS 6060315 yicS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732488.1 3935822 D 316385 CDS YP_001732489.1 170083169 6058456 complement(3936156..3937511) 1 NC_010473.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 3937511 nepI 6058456 nepI Escherichia coli str. K-12 substr. DH10B ribonucleoside transporter YP_001732489.1 3936156 R 316385 CDS YP_001732490.1 170083170 6060083 complement(3937557..3938009) 1 NC_010473.1 hypothetical protein 3938009 yicN 6060083 yicN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732490.1 3937557 R 316385 CDS YP_001732491.1 170083171 6060354 complement(3938062..3939396) 1 NC_010473.1 xanthine/uracil permase 3939396 yicO 6060354 yicO Escherichia coli str. K-12 substr. DH10B xanthine/uracil permase YP_001732491.1 3938062 R 316385 CDS YP_001732492.1 170083172 6058437 3939571..3941337 1 NC_010473.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 3941337 ade 6058437 ade Escherichia coli str. K-12 substr. DH10B cryptic adenine deaminase YP_001732492.1 3939571 D 316385 CDS YP_001732493.1 170083173 6058170 complement(3941383..3942774) 1 NC_010473.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 3942774 uhpT 6058170 uhpT Escherichia coli str. K-12 substr. DH10B sugar phosphate antiporter YP_001732493.1 3941383 R 316385 CDS YP_001732494.1 170083174 6059157 complement(3942912..3944231) 1 NC_010473.1 membrane protein regulates uhpT expression; regulatory protein UhpC 3944231 uhpC 6059157 uhpC Escherichia coli str. K-12 substr. DH10B regulatory protein UhpC YP_001732494.1 3942912 R 316385 CDS YP_001732495.1 170083175 6061098 complement(3944241..3945743) 1 NC_010473.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 3945743 uhpB 6061098 uhpB Escherichia coli str. K-12 substr. DH10B sensory histidine kinase UhpB YP_001732495.1 3944241 R 316385 CDS YP_001732496.1 170083176 6058657 complement(3945743..3946333) 1 NC_010473.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 3946333 uhpA 6058657 uhpA Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator UhpA YP_001732496.1 3945743 R 316385 CDS YP_001732497.1 170083177 6058378 complement(3946409..3946699) 1 NC_010473.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 3946699 ilvN 6058378 ilvN Escherichia coli str. K-12 substr. DH10B acetolactate synthase 1 regulatory subunit YP_001732497.1 3946409 R 316385 CDS YP_001732498.1 170083178 6058513 complement(3946703..3948391) 1 NC_010473.1 acetolactate synthase catalytic subunit 3948391 ilvB 6058513 ilvB Escherichia coli str. K-12 substr. DH10B acetolactate synthase catalytic subunit YP_001732498.1 3946703 R 316385 CDS YP_001732499.1 170083179 6059349 complement(3948497..3948595) 1 NC_010473.1 ilvB operon leader peptide 3948595 ivbL 6059349 ivbL Escherichia coli str. K-12 substr. DH10B ilvB operon leader peptide YP_001732499.1 3948497 R 316385 CDS YP_001732500.1 170083180 6058645 3949529..3950713 1 NC_010473.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 3950713 emrD 6058645 emrD Escherichia coli str. K-12 substr. DH10B multidrug resistance protein D YP_001732500.1 3949529 D 316385 CDS YP_001732501.1 170083181 6062063 complement(3950721..3951218) 1 NC_010473.1 DNA-binding transcriptional regulator 3951218 yidF 6062063 yidF Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732501.1 3950721 R 316385 CDS YP_001732502.1 170083182 6061687 complement(3951215..3951577) 1 NC_010473.1 inner membrane protein 3951577 yidG 6061687 yidG Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732502.1 3951215 R 316385 CDS YP_001732503.1 170083183 6061546 complement(3951567..3951914) 1 NC_010473.1 inner membrane protein 3951914 yidH 6061546 yidH Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732503.1 3951567 R 316385 CDS YP_001732504.1 170083184 6061398 3952022..3952471 1 NC_010473.1 inner membrane protein 3952471 yidI 6061398 yidI Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732504.1 3952022 D 316385 CDS YP_001732505.1 170083185 6061255 complement(3952518..3954011) 1 NC_010473.1 sulfatase/phosphatase 3954011 yidJ 6061255 yidJ Escherichia coli str. K-12 substr. DH10B sulfatase/phosphatase YP_001732505.1 3952518 R 316385 CDS YP_001732506.1 170083186 6061057 complement(3954008..3955723) 1 NC_010473.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK 3955723 yidK 6061057 yidK Escherichia coli str. K-12 substr. DH10B putative symporter YidK YP_001732506.1 3954008 R 316385 CDS YP_001732507.1 170083187 6060904 3955860..3956783 1 NC_010473.1 DNA-binding transcriptional regulator 3956783 yidL 6060904 yidL Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732507.1 3955860 D 316385 CDS YP_001732508.1 170083188 6058840 3959506..3960222 1 NC_010473.1 DNA-binding transcriptional regulator 3960222 yidP 6058840 yidP Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732508.1 3959506 D 316385 CDS YP_001732509.1 170083189 6062125 complement(3960219..3961880) 1 NC_010473.1 hypothetical protein 3961880 yidE 6062125 yidE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732509.1 3960219 R 316385 CDS YP_001732510.1 170083190 6062047 complement(3962076..3962504) 1 NC_010473.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 3962504 ibpB 6062047 ibpB Escherichia coli str. K-12 substr. DH10B heat shock chaperone IbpB YP_001732510.1 3962076 R 316385 CDS YP_001732511.1 170083191 6062008 complement(3962616..3963029) 1 NC_010473.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 3963029 ibpA 6062008 ibpA Escherichia coli str. K-12 substr. DH10B heat shock protein IbpA YP_001732511.1 3962616 R 316385 CDS YP_001732512.1 170083192 6061977 3963335..3963667 1 NC_010473.1 hypothetical protein 3963667 yidQ 6061977 yidQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732512.1 3963335 D 316385 CDS YP_001732513.1 170083193 6061528 complement(3963669..3964883) 1 NC_010473.1 hypothetical protein 3964883 yidR 6061528 yidR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732513.1 3963669 R 316385 CDS YP_001732514.1 170083194 6061550 complement(3966045..3967337) 1 NC_010473.1 D-galactonate transporter 3967337 dgoT 6061550 dgoT Escherichia coli str. K-12 substr. DH10B D-galactonate transporter YP_001732514.1 3966045 R 316385 CDS YP_001732515.1 170083195 6061660 complement(3967457..3968605) 1 NC_010473.1 galactonate dehydratase 3968605 dgoD 6061660 dgoD Escherichia coli str. K-12 substr. DH10B galactonate dehydratase YP_001732515.1 3967457 R 316385 CDS YP_001732516.1 170083196 6061779 complement(3968602..3969219) 1 NC_010473.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 3969219 dgoA 6061779 dgoA Escherichia coli str. K-12 substr. DH10B 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_001732516.1 3968602 R 316385 CDS YP_001732517.1 170083197 6061402 complement(3969203..3970081) 1 NC_010473.1 2-oxo-3-deoxygalactonate kinase 3970081 dgoK 6061402 dgoK Escherichia coli str. K-12 substr. DH10B 2-oxo-3-deoxygalactonate kinase YP_001732517.1 3969203 R 316385 CDS YP_001732518.1 170083198 6061794 complement(3970078..3970767) 1 NC_010473.1 DNA-binding transcriptional regulator 3970767 dgoR 6061794 dgoR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732518.1 3970078 R 316385 CDS YP_001732519.1 170083199 6061922 3971045..3971701 1 NC_010473.1 hypothetical protein 3971701 yidX 6061922 yidX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732519.1 3971045 D 316385 CDS YP_001732520.1 170083200 6059176 complement(3971747..3972559) 1 NC_010473.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 3972559 yidA 6059176 yidA Escherichia coli str. K-12 substr. DH10B sugar phosphatase YP_001732520.1 3971747 R 316385 CDS YP_001732521.1 170083201 6059300 complement(3972674..3973072) 1 NC_010473.1 hypothetical protein 3973072 yidB 6059300 yidB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732521.1 3972674 R 316385 CDS YP_001732522.1 170083202 6059269 complement(3975755..3976828) 1 NC_010473.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3976828 recF 6059269 recF Escherichia coli str. K-12 substr. DH10B recombination protein F YP_001732522.1 3975755 R 316385 CDS YP_001732523.1 170083203 6058510 complement(3976828..3977928) 1 NC_010473.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3977928 dnaN 6058510 dnaN Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit beta YP_001732523.1 3976828 R 316385 CDS YP_001732524.1 170083204 6058237 3979943..3980083 1 NC_010473.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 3980083 rpmH 6058237 rpmH Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L34 YP_001732524.1 3979943 D 316385 CDS YP_001732525.1 170083205 6059155 3980100..3980459 1 NC_010473.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 3980459 rnpA 6059155 rnpA Escherichia coli str. K-12 substr. DH10B ribonuclease P YP_001732525.1 3980100 D 316385 CDS YP_001732526.1 170083206 6059086 3980423..3980680 1 NC_010473.1 hypothetical protein 3980680 yidD 6059086 yidD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732526.1 3980423 D 316385 CDS YP_001732527.1 170083207 6059018 3980683..3982329 1 NC_010473.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3982329 yidC 6059018 yidC Escherichia coli str. K-12 substr. DH10B putative inner membrane protein translocase component YidC YP_001732527.1 3980683 D 316385 CDS YP_001732528.1 170083208 6058961 3982435..3983799 1 NC_010473.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 3983799 trmE 6058961 trmE Escherichia coli str. K-12 substr. DH10B tRNA modification GTPase TrmE YP_001732528.1 3982435 D 316385 CDS YP_001732529.1 170083209 6058912 3984042..3984116 1 NC_010473.1 tryptophanase leader peptide 3984116 tnaC 6058912 tnaC Escherichia coli str. K-12 substr. DH10B tryptophanase leader peptide YP_001732529.1 3984042 D 316385 CDS YP_001732530.1 170083210 6061034 3984337..3985752 1 NC_010473.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 3985752 tnaA 6061034 tnaA Escherichia coli str. K-12 substr. DH10B tryptophanase YP_001732530.1 3984337 D 316385 CDS YP_001732531.1 170083211 6058748 3985843..3987090 1 NC_010473.1 tryptophan transporter of low affinity; tryptophan permease TnaB 3987090 tnaB 6058748 tnaB Escherichia coli str. K-12 substr. DH10B tryptophan permease TnaB YP_001732531.1 3985843 D 316385 CDS YP_001732532.1 170083212 6058706 3987222..3988397 1 NC_010473.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 3988397 mdtL 6058706 mdtL Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein MdtL YP_001732532.1 3987222 D 316385 CDS YP_001732533.1 170083213 6058646 3988372..3989331 1 NC_010473.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 3989331 yidZ 6058646 yidZ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YidZ YP_001732533.1 3988372 D 316385 CDS YP_001732534.1 170083214 6058098 3989476..3990237 1 NC_010473.1 phosphopantetheinyl transferase 3990237 yieE 6058098 yieE Escherichia coli str. K-12 substr. DH10B phosphopantetheinyl transferase YP_001732534.1 3989476 D 316385 CDS YP_001732535.1 170083215 6058522 3990259..3990825 1 NC_010473.1 chromate reductase, class I, flavoprotein 3990825 yieF 6058522 yieF Escherichia coli str. K-12 substr. DH10B chromate reductase, class I, flavoprotein YP_001732535.1 3990259 D 316385 CDS YP_001732536.1 170083216 6058399 complement(3990879..3992216) 1 NC_010473.1 inner membrane protein 3992216 yieG 6058399 yieG Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732536.1 3990879 R 316385 CDS YP_001732537.1 170083217 6058461 3992381..3993046 1 NC_010473.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 3993046 yieH 6058461 yieH Escherichia coli str. K-12 substr. DH10B 6-phosphogluconate phosphatase YP_001732537.1 3992381 D 316385 CDS YP_001732538.1 170083218 6058116 3993113..3993580 1 NC_010473.1 might be involved in hypersensitivity to nitrofurzone; putative inner membrane protein 3993580 yieI 6058116 yieI Escherichia coli str. K-12 substr. DH10B putative inner membrane protein YP_001732538.1 3993113 D 316385 CDS YP_001732539.1 170083219 6060965 3993629..3994216 1 NC_010473.1 hypothetical protein 3994216 cbrC 6060965 cbrC Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732539.1 3993629 D 316385 CDS YP_001732540.1 170083220 6062052 complement(3994278..3995000) 1 NC_010473.1 putative 6-phosphogluconolactonase 3995000 yieK 6062052 yieK Escherichia coli str. K-12 substr. DH10B putative 6-phosphogluconolactonase YP_001732540.1 3994278 R 316385 CDS YP_001732541.1 170083221 6061346 complement(3995015..3996211) 1 NC_010473.1 xylanase 3996211 yieL 6061346 yieL Escherichia coli str. K-12 substr. DH10B xylanase YP_001732541.1 3995015 R 316385 CDS YP_001732542.1 170083222 6059326 complement(3996211..3997827) 1 NC_010473.1 carbohydrate-specific outer membrane porin, cryptic 3997827 bglH 6059326 bglH Escherichia coli str. K-12 substr. DH10B carbohydrate-specific outer membrane porin, cryptic YP_001732542.1 3996211 R 316385 CDS YP_001732543.1 170083223 6061131 complement(3997896..3999308) 1 NC_010473.1 cryptic phospho-beta-glucosidase B 3999308 bglB 6061131 bglB Escherichia coli str. K-12 substr. DH10B cryptic phospho-beta-glucosidase B YP_001732543.1 3997896 R 316385 CDS YP_001732544.1 170083224 6060435 complement(3999327..4001204) 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC 4001204 bglF 6060435 bglF Escherichia coli str. K-12 substr. DH10B PTS system beta-glucoside-specific transporter subunit IIABC YP_001732544.1 3999327 R 316385 CDS YP_001732545.1 170083225 6060235 complement(4001338..4002174) 1 NC_010473.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4002174 bglG 6060235 bglG Escherichia coli str. K-12 substr. DH10B transcriptional antiterminator BglG YP_001732545.1 4001338 R 316385 CDS YP_001732546.1 170083226 6060084 complement(4002460..4003185) 1 NC_010473.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4003185 phoU 6060084 phoU Escherichia coli str. K-12 substr. DH10B transcriptional regulator PhoU YP_001732546.1 4002460 R 316385 CDS YP_001732547.1 170083227 6058315 complement(4003200..4003973) 1 NC_010473.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4003973 pstB 6058315 pstB Escherichia coli str. K-12 substr. DH10B phosphate transporter ATP-binding protein YP_001732547.1 4003200 R 316385 CDS YP_001732548.1 170083228 6058228 complement(4004156..4005046) 1 NC_010473.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4005046 pstA 6058228 pstA Escherichia coli str. K-12 substr. DH10B phosphate transporter permease subunit PtsA YP_001732548.1 4004156 R 316385 CDS YP_001732549.1 170083229 6058429 complement(4005046..4006005) 1 NC_010473.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4006005 pstC 6058429 pstC Escherichia coli str. K-12 substr. DH10B phosphate transporter permease subunit PstC YP_001732549.1 4005046 R 316385 CDS YP_001732550.1 170083230 6060017 complement(4006092..4007132) 1 NC_010473.1 phosphate ABC transporter substrate-binding protein 4007132 pstS 6060017 pstS Escherichia coli str. K-12 substr. DH10B phosphate ABC transporter substrate-binding protein YP_001732550.1 4006092 R 316385 CDS YP_001732551.1 170083231 6059870 complement(4009437..4010807) 1 NC_010473.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4010807 glmU 6059870 glmU Escherichia coli str. K-12 substr. DH10B bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001732551.1 4009437 R 316385 CDS YP_001732552.1 170083232 6062003 complement(4011160..4011579) 1 NC_010473.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 4011579 atpC 6062003 atpC Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit epsilon YP_001732552.1 4011160 R 316385 CDS YP_001732553.1 170083233 6058271 complement(4011600..4012982) 1 NC_010473.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 4012982 atpD 6058271 atpD Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit beta YP_001732553.1 4011600 R 316385 CDS YP_001732554.1 170083234 6059435 complement(4013009..4013872) 1 NC_010473.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 4013872 atpG 6059435 atpG Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit gamma YP_001732554.1 4013009 R 316385 CDS YP_001732555.1 170083235 6060798 complement(4013923..4015464) 1 NC_010473.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 4015464 atpA 6060798 atpA Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit alpha YP_001732555.1 4013923 R 316385 CDS YP_001732556.1 170083236 6061478 complement(4015477..4016010) 1 NC_010473.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 4016010 atpH 6061478 atpH Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit delta YP_001732556.1 4015477 R 316385 CDS YP_001732557.1 170083237 6060491 complement(4016025..4016495) 1 NC_010473.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 4016495 atpF 6060491 atpF Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit B YP_001732557.1 4016025 R 316385 CDS YP_001732558.1 170083238 6061741 complement(4016557..4016796) 1 NC_010473.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 4016796 atpE 6061741 atpE Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit C YP_001732558.1 4016557 R 316385 CDS YP_001732559.1 170083239 6060643 complement(4016843..4017658) 1 NC_010473.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 4017658 atpB 6060643 atpB Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit A YP_001732559.1 4016843 R 316385 CDS YP_001732560.1 170083240 6060503 complement(4017667..4018047) 1 NC_010473.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4018047 atpI 6060503 atpI Escherichia coli str. K-12 substr. DH10B F0F1 ATP synthase subunit I YP_001732560.1 4017667 R 316385 CDS YP_001732561.1 170083241 6060614 complement(4018664..4019287) 1 NC_010473.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4019287 gidB 6060614 gidB Escherichia coli str. K-12 substr. DH10B 16S rRNA methyltransferase GidB YP_001732561.1 4018664 R 316385 CDS YP_001732562.1 170083242 6058463 complement(4019351..4021240) 1 NC_010473.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4021240 gidA 6058463 gidA Escherichia coli str. K-12 substr. DH10B tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001732562.1 4019351 R 316385 CDS YP_001732563.1 170083243 6061156 complement(4021619..4022062) 1 NC_010473.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4022062 mioC 6061156 mioC Escherichia coli str. K-12 substr. DH10B flavodoxin YP_001732563.1 4021619 R 316385 CDS YP_001732564.1 170083244 6058775 complement(4022152..4022610) 1 NC_010473.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4022610 asnC 6058775 asnC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator AsnC YP_001732564.1 4022152 R 316385 CDS YP_001732565.1 170083245 6060092 4022762..4023754 1 NC_010473.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4023754 asnA 6060092 asnA Escherichia coli str. K-12 substr. DH10B asparagine synthetase AsnA YP_001732565.1 4022762 D 316385 CDS YP_001732566.1 170083246 6058504 complement(4023759..4025210) 1 NC_010473.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4025210 yieM 6058504 yieM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732566.1 4023759 R 316385 CDS YP_001732567.1 170083247 6060369 4026923..4028791 1 NC_010473.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4028791 trkD 6060369 trkD Escherichia coli str. K-12 substr. DH10B potassium transport protein Kup YP_001732567.1 4026923 D 316385 CDS YP_001732568.1 170083248 6058554 4028958..4029377 1 NC_010473.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4029377 rbsD 6058554 rbsD Escherichia coli str. K-12 substr. DH10B D-ribose pyranase YP_001732568.1 4028958 D 316385 CDS YP_001732569.1 170083249 6058276 4029385..4030890 1 NC_010473.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4030890 rbsA 6058276 rbsA Escherichia coli str. K-12 substr. DH10B D-ribose transporter ATP-binding protein YP_001732569.1 4029385 D 316385 CDS YP_001732570.1 170083250 6058219 4030895..4031860 1 NC_010473.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4031860 rbsC 6058219 rbsC Escherichia coli str. K-12 substr. DH10B ribose ABC transporter permease YP_001732570.1 4030895 D 316385 CDS YP_001732571.1 170083251 6059788 4031885..4032775 1 NC_010473.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4032775 rbsB 6059788 rbsB Escherichia coli str. K-12 substr. DH10B D-ribose transporter subunit RbsB YP_001732571.1 4031885 D 316385 CDS YP_001732572.1 170083252 6061440 4032901..4033830 1 NC_010473.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4033830 rbsK 6061440 rbsK Escherichia coli str. K-12 substr. DH10B ribokinase YP_001732572.1 4032901 D 316385 CDS YP_001732573.1 170083253 6061408 complement(4036128..4037555) 1 NC_010473.1 multidrug or homocysteine efflux system 4037555 hsrA 6061408 hsrA Escherichia coli str. K-12 substr. DH10B multidrug or homocysteine efflux system YP_001732573.1 4036128 R 316385 CDS YP_001732574.1 170083254 6058774 complement(4037578..4038270) 1 NC_010473.1 transcriptional regulator 4038270 yieP 6058774 yieP Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001732574.1 4037578 R 316385 CDS YP_001732575.1 170083255 6061021 complement(4044071..4044910) 1 NC_010473.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4044910 hdfR 6061021 hdfR Escherichia coli str. K-12 substr. DH10B transcriptional regulator HdfR YP_001732575.1 4044071 R 316385 CDS YP_001732576.1 170083256 6060651 4045029..4045367 1 NC_010473.1 hypothetical protein 4045367 yifE 6060651 yifE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732576.1 4045029 D 316385 CDS YP_001732577.1 170083257 6058459 complement(4045392..4046942) 1 NC_010473.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease 4046942 yifB 6058459 yifB Escherichia coli str. K-12 substr. DH10B putative ATP-dependent protease YP_001732577.1 4045392 R 316385 CDS YP_001732578.1 170083258 6058561 4047265..4047363 1 NC_010473.1 ilvG operon leader peptide 4047363 ilvL 6058561 ilvL Escherichia coli str. K-12 substr. DH10B ilvG operon leader peptide YP_001732578.1 4047265 D 316385 CDS YP_001732579.1 170083259 6058436 4049144..4049407 1 NC_010473.1 acetolactate synthase 2 regulatory subunit 4049407 ilvM 6058436 ilvM Escherichia coli str. K-12 substr. DH10B acetolactate synthase 2 regulatory subunit YP_001732579.1 4049144 D 316385 CDS YP_001732580.1 170083260 6058370 4049427..4050356 1 NC_010473.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4050356 ilvE 6058370 ilvE Escherichia coli str. K-12 substr. DH10B branched-chain amino acid aminotransferase YP_001732580.1 4049427 D 316385 CDS YP_001732581.1 170083261 6058988 4052274..4053818 1 NC_010473.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4053818 ilvA 6058988 ilvA Escherichia coli str. K-12 substr. DH10B threonine dehydratase YP_001732581.1 4052274 D 316385 CDS YP_001732582.1 170083262 6059375 complement(4053870..4054763) 1 NC_010473.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4054763 ilvY 6059375 ilvY Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator IlvY YP_001732582.1 4053870 R 316385 CDS YP_001732583.1 170083263 6059704 4054913..4056388 1 NC_010473.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4056388 ilvC 6059704 ilvC Escherichia coli str. K-12 substr. DH10B ketol-acid reductoisomerase YP_001732583.1 4054913 D 316385 CDS YP_001732584.1 170083264 6062187 complement(4056475..4056756) 1 NC_010473.1 peptidyl-prolyl cis-trans isomerase C 4056756 ppiC 6062187 ppiC Escherichia coli str. K-12 substr. DH10B peptidyl-prolyl cis-trans isomerase C YP_001732584.1 4056475 R 316385 CDS YP_001732585.1 170083265 6059691 4057620..4059641 1 NC_010473.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4059641 rep 6059691 rep Escherichia coli str. K-12 substr. DH10B ATP-dependent DNA helicase Rep YP_001732585.1 4057620 D 316385 CDS YP_001732586.1 170083266 6061985 complement(4059688..4061172) 1 NC_010473.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4061172 gpp 6061985 gpp Escherichia coli str. K-12 substr. DH10B guanosine pentaphosphate phosphohydrolase YP_001732586.1 4059688 R 316385 CDS YP_001732587.1 170083267 6061836 complement(4061308..4062573) 1 NC_010473.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4062573 rhlB 6061836 rhlB Escherichia coli str. K-12 substr. DH10B ATP-dependent RNA helicase RhlB YP_001732587.1 4061308 R 316385 CDS YP_001732588.1 170083268 6061668 4062704..4063033 1 NC_010473.1 thioredoxin 4063033 trxA 6061668 trxA Escherichia coli str. K-12 substr. DH10B thioredoxin YP_001732588.1 4062704 D 316385 CDS YP_001732589.1 170083269 6061627 4063174..4063275 1 NC_010473.1 putative rho operon leader peptide 4063275 rhoL 6061627 rhoL Escherichia coli str. K-12 substr. DH10B putative rho operon leader peptide YP_001732589.1 4063174 D 316385 CDS YP_001732590.1 170083270 6061516 4063360..4064619 1 NC_010473.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4064619 rho 6061516 rho Escherichia coli str. K-12 substr. DH10B transcription termination factor Rho YP_001732590.1 4063360 D 316385 CDS YP_001732591.1 170083271 6061498 4064859..4065962 1 NC_010473.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 4065962 rfe 6061498 rfe Escherichia coli str. K-12 substr. DH10B undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase YP_001732591.1 4064859 D 316385 CDS YP_001732592.1 170083272 6061323 4065974..4067020 1 NC_010473.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4067020 wzzE 6061323 wzzE Escherichia coli str. K-12 substr. DH10B lipopolysaccharide biosynthesis protein WzzE YP_001732592.1 4065974 D 316385 CDS YP_001732593.1 170083273 6061290 4067076..4068206 1 NC_010473.1 UDP-N-acetylglucosamine 2-epimerase 4068206 rffE 6061290 rffE Escherichia coli str. K-12 substr. DH10B UDP-N-acetylglucosamine 2-epimerase YP_001732593.1 4067076 D 316385 CDS YP_001732594.1 170083274 6061175 4068203..4069465 1 NC_010473.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4069465 wecC 6061175 wecC Escherichia coli str. K-12 substr. DH10B UDP-N-acetyl-D-mannosamine dehydrogenase YP_001732594.1 4068203 D 316385 CDS YP_001732595.1 170083275 6061151 4069465..4070532 1 NC_010473.1 dTDP-glucose 4,6-dehydratase 4070532 rffG 6061151 rffG Escherichia coli str. K-12 substr. DH10B dTDP-glucose 4,6-dehydratase YP_001732595.1 4069465 D 316385 CDS YP_001732596.1 170083276 6061020 4070551..4071432 1 NC_010473.1 glucose-1-phosphate thymidylyltransferase 4071432 rffH 6061020 rffH Escherichia coli str. K-12 substr. DH10B glucose-1-phosphate thymidylyltransferase YP_001732596.1 4070551 D 316385 CDS YP_001732597.1 170083277 6060940 4071410..4072084 1 NC_010473.1 TDP-fucosamine acetyltransferase 4072084 rffC 6060940 rffC Escherichia coli str. K-12 substr. DH10B TDP-fucosamine acetyltransferase YP_001732597.1 4071410 D 316385 CDS YP_001732598.1 170083278 6060889 4072089..4073219 1 NC_010473.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4073219 rffA 6060889 rffA Escherichia coli str. K-12 substr. DH10B TDP-4-oxo-6-deoxy-D-glucose transaminase YP_001732598.1 4072089 D 316385 CDS YP_001732599.1 170083279 6060806 4073221..4074471 1 NC_010473.1 lipid III translocase 4074471 wzxE 6060806 wzxE Escherichia coli str. K-12 substr. DH10B lipid III translocase YP_001732599.1 4073221 D 316385 CDS YP_001732600.1 170083280 6060579 4074468..4075547 1 NC_010473.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4075547 rffT 6060579 rffT Escherichia coli str. K-12 substr. DH10B 4-alpha-L-fucosyltransferase YP_001732600.1 4074468 D 316385 CDS YP_001732601.1 170083281 6060539 4075544..4076896 1 NC_010473.1 enterobacterial common antigen polymerase; putative common antigen polymerase 4076896 wzyE 6060539 wzyE Escherichia coli str. K-12 substr. DH10B putative common antigen polymerase YP_001732601.1 4075544 D 316385 CDS YP_001732602.1 170083282 6061124 4076899..4077639 1 NC_010473.1 putative UDP-N-acetyl-D-mannosaminuronic acid transferase 4077639 rffM 6061124 rffM Escherichia coli str. K-12 substr. DH10B putative UDP-N-acetyl-D-mannosaminuronic acid transferase YP_001732602.1 4076899 D 316385 CDS YP_001732603.1 170083283 6061103 4077830..4079215 1 NC_010473.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK 4079215 yifK 6061103 yifK Escherichia coli str. K-12 substr. DH10B putative transport protein YifK YP_001732603.1 4077830 D 316385 CDS YP_001732604.1 170083284 6060540 4079901..4081136 1 NC_010473.1 regulator of arylsulfatase activity 4081136 aslB 6060540 aslB Escherichia coli str. K-12 substr. DH10B regulator of arylsulfatase activity YP_001732604.1 4079901 D 316385 CDS YP_001732605.1 170083285 6061059 complement(4081295..4082950) 1 NC_010473.1 acrylsulfatase-like protein 4082950 aslA 6061059 aslA Escherichia coli str. K-12 substr. DH10B acrylsulfatase-like protein YP_001732605.1 4081295 R 316385 CDS YP_001732606.1 170083286 6061393 complement(4083629..4084825) 1 NC_010473.1 putative protoheme IX biogenesis protein 4084825 hemY 6061393 hemY Escherichia coli str. K-12 substr. DH10B putative protoheme IX biogenesis protein YP_001732606.1 4083629 R 316385 CDS YP_001732607.1 170083287 6060968 complement(4086031..4086771) 1 NC_010473.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4086771 hemD 6060968 hemD Escherichia coli str. K-12 substr. DH10B uroporphyrinogen-III synthase YP_001732607.1 4086031 R 316385 CDS YP_001732608.1 170083288 6060627 complement(4086768..4087709) 1 NC_010473.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4087709 hemC 6060627 hemC Escherichia coli str. K-12 substr. DH10B porphobilinogen deaminase YP_001732608.1 4086768 R 316385 CDS YP_001732609.1 170083289 6060988 complement(4090682..4091002) 1 NC_010473.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4091002 cyaY 6060988 cyaY Escherichia coli str. K-12 substr. DH10B frataxin-like protein YP_001732609.1 4090682 R 316385 CDS YP_001732610.1 170083290 6061750 4090793..4091278 1 NC_010473.1 hypothetical protein 4091278 yzcX 6061750 yzcX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732610.1 4090793 D 316385 CDS YP_001732611.1 170083291 6061632 4091465..4091668 1 NC_010473.1 lipoprotein 4091668 yifL 6061632 yifL Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001732611.1 4091465 D 316385 CDS YP_001732612.1 170083292 6061568 4091705..4092529 1 NC_010473.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4092529 dapF 6061568 dapF Escherichia coli str. K-12 substr. DH10B diaminopimelate epimerase YP_001732612.1 4091705 D 316385 CDS YP_001732613.1 170083293 6060597 4093230..4094126 1 NC_010473.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4094126 xerC 6060597 xerC Escherichia coli str. K-12 substr. DH10B site-specific tyrosine recombinase XerC YP_001732613.1 4093230 D 316385 CDS YP_001732614.1 170083294 6060825 4094126..4094842 1 NC_010473.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4094842 yigB 6060825 yigB Escherichia coli str. K-12 substr. DH10B flavin mononucleotide phosphatase YP_001732614.1 4094126 D 316385 CDS YP_001732615.1 170083295 6061671 4094926..4097088 1 NC_010473.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4097088 uvrD 6061671 uvrD Escherichia coli str. K-12 substr. DH10B DNA-dependent helicase II YP_001732615.1 4094926 D 316385 CDS YP_001732616.1 170083296 6060916 complement(4097235..4097999) 1 NC_010473.1 hypothetical protein 4097999 yigE 6060916 yigE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732616.1 4097235 R 316385 CDS YP_001732617.1 170083297 6061869 4098369..4099319 1 NC_010473.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4099319 corA 6061869 corA Escherichia coli str. K-12 substr. DH10B magnesium/nickel/cobalt transporter CorA YP_001732617.1 4098369 D 316385 CDS YP_001732618.1 170083298 6061482 complement(4099362..4099742) 1 NC_010473.1 inner membrane protein 4099742 yigF 6061482 yigF Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732618.1 4099362 R 316385 CDS YP_001732619.1 170083299 6060721 complement(4099756..4100136) 1 NC_010473.1 hypothetical protein 4100136 yigG 6060721 yigG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732619.1 4099756 R 316385 CDS YP_001732620.1 170083300 6060866 complement(4100231..4101121) 1 NC_010473.1 chloramphenical resistance permease 4101121 rarD 6060866 rarD Escherichia coli str. K-12 substr. DH10B chloramphenical resistance permease YP_001732620.1 4100231 R 316385 CDS YP_001732621.1 170083301 6060944 complement(4101173..4101640) 1 NC_010473.1 hypothetical protein 4101640 yigI 6060944 yigI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732621.1 4101173 R 316385 CDS YP_001732622.1 170083302 6058105 4101805..4102674 1 NC_010473.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4102674 pldA 6058105 pldA Escherichia coli str. K-12 substr. DH10B phospholipase A YP_001732622.1 4101805 D 316385 CDS YP_001732623.1 170083303 6059482 4102807..4104636 1 NC_010473.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4104636 recQ 6059482 recQ Escherichia coli str. K-12 substr. DH10B ATP-dependent DNA helicase RecQ YP_001732623.1 4102807 D 316385 CDS YP_001732624.1 170083304 6061914 4104700..4105320 1 NC_010473.1 threonine efflux system 4105320 rhtC 6061914 rhtC Escherichia coli str. K-12 substr. DH10B threonine efflux system YP_001732624.1 4104700 D 316385 CDS YP_001732625.1 170083305 6059312 complement(4105382..4106002) 1 NC_010473.1 homoserine/homoserine lactone efflux protein 4106002 rhtB 6059312 rhtB Escherichia coli str. K-12 substr. DH10B homoserine/homoserine lactone efflux protein YP_001732625.1 4105382 R 316385 CDS YP_001732626.1 170083306 6059297 4106113..4107135 1 NC_010473.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4107135 pldB 6059297 pldB Escherichia coli str. K-12 substr. DH10B lysophospholipase L2 YP_001732626.1 4106113 D 316385 CDS YP_001732627.1 170083307 6059290 4107143..4107943 1 NC_010473.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase 4107943 yigL 6059290 yigL Escherichia coli str. K-12 substr. DH10B putative sugar phosphatase YP_001732627.1 4107143 D 316385 CDS YP_001732628.1 170083308 6059225 complement(4108806..4109759) 1 NC_010473.1 DNA-binding transcriptional activator, homocysteine-binding 4109759 metR 6059225 metR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator, homocysteine-binding YP_001732628.1 4108806 R 316385 CDS YP_001732629.1 170083309 6059211 4109996..4112257 1 NC_010473.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4112257 metE 6059211 metE Escherichia coli str. K-12 substr. DH10B 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001732629.1 4109996 D 316385 CDS YP_001732630.1 170083310 6058274 complement(4112297..4113112) 1 NC_010473.1 hydrolase 4113112 ysgA 6058274 ysgA Escherichia coli str. K-12 substr. DH10B hydrolase YP_001732630.1 4112297 R 316385 CDS YP_001732631.1 170083311 6062352 4113374..4114135 1 NC_010473.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4114135 udp 6062352 udp Escherichia coli str. K-12 substr. DH10B uridine phosphorylase YP_001732631.1 4113374 D 316385 CDS YP_001732632.1 170083312 6058334 4114276..4115703 1 NC_010473.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4115703 rmuC 6058334 rmuC Escherichia coli str. K-12 substr. DH10B DNA recombination protein RmuC YP_001732632.1 4114276 D 316385 CDS YP_001732633.1 170083313 6060314 4115798..4116553 1 NC_010473.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4116553 ubiE 6060314 ubiE Escherichia coli str. K-12 substr. DH10B ubiquinone/menaquinone biosynthesis methyltransferase YP_001732633.1 4115798 D 316385 CDS YP_001732634.1 170083314 6059141 4116567..4117172 1 NC_010473.1 hypothetical protein 4117172 yigP 6059141 yigP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732634.1 4116567 D 316385 CDS YP_001732635.1 170083315 6059192 4117169..4118809 1 NC_010473.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 4118809 ubiB 6059192 ubiB Escherichia coli str. K-12 substr. DH10B putative ubiquinone biosynthesis protein UbiB YP_001732635.1 4117169 D 316385 CDS YP_001732636.1 170083316 6059162 4118888..4119157 1 NC_010473.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4119157 tatA 6059162 tatA Escherichia coli str. K-12 substr. DH10B twin arginine translocase protein A YP_001732636.1 4118888 D 316385 CDS YP_001732637.1 170083317 6060545 4119161..4119676 1 NC_010473.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4119676 tatB 6060545 tatB Escherichia coli str. K-12 substr. DH10B sec-independent translocase YP_001732637.1 4119161 D 316385 CDS YP_001732638.1 170083318 6059036 4119679..4120455 1 NC_010473.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4120455 tatC 6059036 tatC Escherichia coli str. K-12 substr. DH10B twin-arginine protein translocation system subunit TatC YP_001732638.1 4119679 D 316385 CDS YP_001732639.1 170083319 6059048 4120497..4121279 1 NC_010473.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4121279 tatD 6059048 tatD Escherichia coli str. K-12 substr. DH10B DNase TatD YP_001732639.1 4120497 D 316385 CDS YP_001732640.1 170083320 6058984 complement(4121276..4121764) 1 NC_010473.1 transcriptional activator RfaH 4121764 rfaH 6058984 rfaH Escherichia coli str. K-12 substr. DH10B transcriptional activator RfaH YP_001732640.1 4121276 R 316385 CDS YP_001732641.1 170083321 6059020 4121931..4123424 1 NC_010473.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4123424 ubiD 6059020 ubiD Escherichia coli str. K-12 substr. DH10B 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001732641.1 4121931 D 316385 CDS YP_001732642.1 170083322 6061282 4123470..4124171 1 NC_010473.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4124171 fre 6061282 fre Escherichia coli str. K-12 substr. DH10B FMN reductase YP_001732642.1 4123470 D 316385 CDS YP_001732643.1 170083323 6061185 complement(4124552..4125715) 1 NC_010473.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4125715 fadA 6061185 fadA Escherichia coli str. K-12 substr. DH10B 3-ketoacyl-CoA thiolase YP_001732643.1 4124552 R 316385 CDS YP_001732644.1 170083324 6058879 complement(4125725..4127914) 1 NC_010473.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4127914 fadB 6058879 fadB Escherichia coli str. K-12 substr. DH10B multifunctional fatty acid oxidation complex subunit alpha YP_001732644.1 4125725 R 316385 CDS YP_001732645.1 170083325 6061092 4128104..4129435 1 NC_010473.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4129435 pepQ 6061092 pepQ Escherichia coli str. K-12 substr. DH10B proline dipeptidase YP_001732645.1 4128104 D 316385 CDS YP_001732646.1 170083326 6058801 4129435..4130049 1 NC_010473.1 hypothetical protein 4130049 yigZ 6058801 yigZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732646.1 4129435 D 316385 CDS YP_001732647.1 170083327 6058816 4130088..4131539 1 NC_010473.1 potassium transporter 4131539 trkH 6058816 trkH Escherichia coli str. K-12 substr. DH10B potassium transporter YP_001732647.1 4130088 D 316385 CDS YP_001732648.1 170083328 6058727 4131551..4132096 1 NC_010473.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4132096 hemG 6058727 hemG Escherichia coli str. K-12 substr. DH10B protoporphyrinogen oxidase YP_001732648.1 4131551 D 316385 CDS YP_001732649.1 170083329 6060868 complement(4137849..4138361) 1 NC_010473.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4138361 mobB 6060868 mobB Escherichia coli str. K-12 substr. DH10B molybdopterin-guanine dinucleotide biosynthesis protein B YP_001732649.1 4137849 R 316385 CDS YP_001732650.1 170083330 6058667 complement(4138358..4138942) 1 NC_010473.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4138942 mobA 6058667 mobA Escherichia coli str. K-12 substr. DH10B molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_001732650.1 4138358 R 316385 CDS YP_001732651.1 170083331 6058671 4139012..4139281 1 NC_010473.1 hypothetical protein 4139281 yihD 6058671 yihD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732651.1 4139012 D 316385 CDS YP_001732652.1 170083332 6058523 4139358..4140344 1 NC_010473.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4140344 yihE 6058523 yihE Escherichia coli str. K-12 substr. DH10B serine/threonine protein kinase YP_001732652.1 4139358 D 316385 CDS YP_001732653.1 170083333 6058256 4140361..4140987 1 NC_010473.1 protein disulfide isomerase I 4140987 dsbA 6058256 dsbA Escherichia coli str. K-12 substr. DH10B protein disulfide isomerase I YP_001732653.1 4140361 D 316385 CDS YP_001732654.1 170083334 6058337 4141142..4142572 1 NC_010473.1 hypothetical protein 4142572 yihF 6058337 yihF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732654.1 4141142 D 316385 CDS YP_001732655.1 170083335 6058383 complement(4142613..4143545) 1 NC_010473.1 putative acyltransferase 4143545 yihG 6058383 yihG Escherichia coli str. K-12 substr. DH10B putative acyltransferase YP_001732655.1 4142613 R 316385 CDS YP_001732656.1 170083336 6058570 4143909..4146695 1 NC_010473.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4146695 polA 6058570 polA Escherichia coli str. K-12 substr. DH10B DNA polymerase I YP_001732656.1 4143909 D 316385 CDS YP_001732657.1 170083337 6061913 complement(4147076..4147672) 1 NC_010473.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4147672 engB 6061913 engB Escherichia coli str. K-12 substr. DH10B ribosome biogenesis GTP-binding protein YsxC YP_001732657.1 4147076 R 316385 CDS YP_001732658.1 170083338 6061025 4148290..4148799 1 NC_010473.1 hypothetical protein 4148799 yihI 6061025 yihI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732658.1 4148290 D 316385 CDS YP_001732659.1 170083339 6058495 4148988..4150361 1 NC_010473.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4150361 hemN 6058495 hemN Escherichia coli str. K-12 substr. DH10B coproporphyrinogen III oxidase YP_001732659.1 4148988 D 316385 CDS YP_001732660.1 170083340 6058394 complement(4150812..4152221) 1 NC_010473.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4152221 glnG 6058394 glnG Escherichia coli str. K-12 substr. DH10B nitrogen regulation protein NR(I) YP_001732660.1 4150812 R 316385 CDS YP_001732661.1 170083341 6058188 complement(4152233..4153282) 1 NC_010473.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4153282 glnL 6058188 glnL Escherichia coli str. K-12 substr. DH10B nitrogen regulation protein NR(II) YP_001732661.1 4152233 R 316385 CDS YP_001732662.1 170083342 6060875 complement(4153568..4154977) 1 NC_010473.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4154977 glnA 6060875 glnA Escherichia coli str. K-12 substr. DH10B glutamine synthetase YP_001732662.1 4153568 R 316385 CDS YP_001732663.1 170083343 6062333 4155350..4157173 1 NC_010473.1 GTP-binding protein 4157173 bipA 6062333 bipA Escherichia coli str. K-12 substr. DH10B GTP-binding protein YP_001732663.1 4155350 D 316385 CDS YP_001732664.1 170083344 6059605 4157390..4158100 1 NC_010473.1 DNA-binding transcriptional regulator 4158100 yihL 6059605 yihL Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732664.1 4157390 D 316385 CDS YP_001732665.1 170083345 6059523 4158108..4159088 1 NC_010473.1 sugar phosphate isomerase 4159088 yihM 6059523 yihM Escherichia coli str. K-12 substr. DH10B sugar phosphate isomerase YP_001732665.1 4158108 D 316385 CDS YP_001732666.1 170083346 6059512 4159190..4160455 1 NC_010473.1 transporter 4160455 yihN 6059512 yihN Escherichia coli str. K-12 substr. DH10B transporter YP_001732666.1 4159190 D 316385 CDS YP_001732667.1 170083347 6059379 complement(4160546..4161238) 1 NC_010473.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L 4161238 ompL 6059379 ompL Escherichia coli str. K-12 substr. DH10B outer membrane porin L YP_001732667.1 4160546 R 316385 CDS YP_001732668.1 170083348 6059917 complement(4161306..4162709) 1 NC_010473.1 predited transporter 4162709 yihO 6059917 yihO Escherichia coli str. K-12 substr. DH10B predited transporter YP_001732668.1 4161306 R 316385 CDS YP_001732669.1 170083349 6059922 complement(4162752..4164158) 1 NC_010473.1 transporter 4164158 yihP 6059922 yihP Escherichia coli str. K-12 substr. DH10B transporter YP_001732669.1 4162752 R 316385 CDS YP_001732670.1 170083350 6059929 complement(4164183..4166219) 1 NC_010473.1 alpha-glucosidase 4166219 yihQ 6059929 yihQ Escherichia coli str. K-12 substr. DH10B alpha-glucosidase YP_001732670.1 4164183 R 316385 CDS YP_001732671.1 170083351 6060355 complement(4167195..4168121) 1 NC_010473.1 aldose-1-epimerase 4168121 yihR 6060355 yihR Escherichia coli str. K-12 substr. DH10B aldose-1-epimerase YP_001732671.1 4167195 R 316385 CDS YP_001732672.1 170083352 6060381 complement(4168235..4169476) 1 NC_010473.1 glucosamine isomerase 4169476 yihS 6060381 yihS Escherichia coli str. K-12 substr. DH10B glucosamine isomerase YP_001732672.1 4168235 R 316385 CDS YP_001732673.1 170083353 6060488 complement(4169493..4170371) 1 NC_010473.1 aldolase 4170371 yihT 6060488 yihT Escherichia coli str. K-12 substr. DH10B aldolase YP_001732673.1 4169493 R 316385 CDS YP_001732674.1 170083354 6062301 complement(4170395..4171291) 1 NC_010473.1 oxidoreductase 4171291 yihU 6062301 yihU Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001732674.1 4170395 R 316385 CDS YP_001732675.1 170083355 6062329 4171459..4172355 1 NC_010473.1 sugar kinase 4172355 yihV 6062329 yihV Escherichia coli str. K-12 substr. DH10B sugar kinase YP_001732675.1 4171459 D 316385 CDS YP_001732676.1 170083356 6062343 4172389..4173174 1 NC_010473.1 DNA-binding transcriptional regulator 4173174 yihW 6062343 yihW Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732676.1 4172389 D 316385 CDS YP_001732677.1 170083357 6062399 4173273..4173872 1 NC_010473.1 phosphatase 4173872 yihX 6062399 yihX Escherichia coli str. K-12 substr. DH10B phosphatase YP_001732677.1 4173273 D 316385 CDS YP_001732678.1 170083358 6060471 4173866..4174738 1 NC_010473.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4174738 rbn 6060471 rbn Escherichia coli str. K-12 substr. DH10B ribonuclease BN YP_001732678.1 4173866 D 316385 CDS YP_001732679.1 170083359 6058978 4174735..4175172 1 NC_010473.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4175172 dtd 6058978 dtd Escherichia coli str. K-12 substr. DH10B D-tyrosyl-tRNA(Tyr) deacylase YP_001732679.1 4174735 D 316385 CDS YP_001732680.1 170083360 6059471 4175169..4176158 1 NC_010473.1 acetyltransferase 4176158 yiiD 6059471 yiiD Escherichia coli str. K-12 substr. DH10B acetyltransferase YP_001732680.1 4175169 D 316385 CDS YP_001732681.1 170083361 6058472 4177011..4177229 1 NC_010473.1 transcriptional regulator 4177229 yiiE 6058472 yiiE Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001732681.1 4177011 D 316385 CDS YP_001732682.1 170083362 6058590 4177471..4177689 1 NC_010473.1 hypothetical protein 4177689 yiiF 6058590 yiiF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732682.1 4177471 D 316385 CDS YP_001732683.1 170083363 6060040 complement(4178019..4178948) 1 NC_010473.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4178948 fdhE 6060040 fdhE Escherichia coli str. K-12 substr. DH10B formate dehydrogenase accessory protein FdhE YP_001732683.1 4178019 R 316385 CDS YP_001732684.1 170083364 6059355 complement(4178945..4179580) 1 NC_010473.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4179580 fdoI 6059355 fdoI Escherichia coli str. K-12 substr. DH10B formate dehydrogenase-O subunit gamma YP_001732684.1 4178945 R 316385 CDS YP_001732685.1 170083365 6059184 complement(4179577..4180479) 1 NC_010473.1 formate dehydrogenase-O, Fe-S subunit 4180479 fdoH 6059184 fdoH Escherichia coli str. K-12 substr. DH10B formate dehydrogenase-O, Fe-S subunit YP_001732685.1 4179577 R 316385 CDS YP_001732686.1 170083366 6061545 complement(4180492..4183542) 1 NC_010473.1 contains the nonsynonymous change N307T; formate dehydrogenase-O, large subunit 4183542 fdoG 6061545 fdoG Escherichia coli str. K-12 substr. DH10B formate dehydrogenase-O, large subunit YP_001732686.1 4180492 R 316385 CDS YP_001732687.1 170083367 6061431 4183736..4184569 1 NC_010473.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4184569 fdhD 6061431 fdhD Escherichia coli str. K-12 substr. DH10B formate dehydrogenase accessory protein YP_001732687.1 4183736 D 316385 CDS YP_001732688.1 170083368 6061296 4184722..4185777 1 NC_010473.1 hypothetical protein 4185777 yiiG 6061296 yiiG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732688.1 4184722 D 316385 CDS YP_001732689.1 170083369 6061300 complement(4185827..4187575) 1 NC_010473.1 putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; putative frv operon regulatory protein 4187575 frvR 6061300 frvR Escherichia coli str. K-12 substr. DH10B putative frv operon regulatory protein YP_001732689.1 4185827 R 316385 CDS YP_001732690.1 170083370 6061305 complement(4187575..4188645) 1 NC_010473.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; putative fructose-specific phosphotransferase system protein FrvX 4188645 frvX 6061305 frvX Escherichia coli str. K-12 substr. DH10B putative fructose-specific phosphotransferase system protein FrvX YP_001732690.1 4187575 R 316385 CDS YP_001732691.1 170083371 6061352 complement(4188635..4190086) 1 NC_010473.1 putative PTS system transporter subunits IIBC 4190086 frvB 6061352 frvB Escherichia coli str. K-12 substr. DH10B putative PTS system transporter subunits IIBC YP_001732691.1 4188635 R 316385 CDS YP_001732692.1 170083372 6061273 complement(4190844..4191158) 1 NC_010473.1 L-rhamnose mutarotase 4191158 yiiL 6061273 yiiL Escherichia coli str. K-12 substr. DH10B L-rhamnose mutarotase YP_001732692.1 4190844 R 316385 CDS YP_001732693.1 170083373 6062228 complement(4191168..4191992) 1 NC_010473.1 rhamnulose-1-phosphate aldolase 4191992 rhaD 6062228 rhaD Escherichia coli str. K-12 substr. DH10B rhamnulose-1-phosphate aldolase YP_001732693.1 4191168 R 316385 CDS YP_001732694.1 170083374 6061366 complement(4192443..4193702) 1 NC_010473.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4193702 rhaA 6061366 rhaA Escherichia coli str. K-12 substr. DH10B L-rhamnose isomerase YP_001732694.1 4192443 R 316385 CDS YP_001732695.1 170083375 6060283 complement(4193699..4195168) 1 NC_010473.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4195168 rhaB 6060283 rhaB Escherichia coli str. K-12 substr. DH10B rhamnulokinase YP_001732695.1 4193699 R 316385 CDS YP_001732696.1 170083376 6061198 4195456..4196292 1 NC_010473.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4196292 rhaS 6061198 rhaS Escherichia coli str. K-12 substr. DH10B transcriptional activator RhaS YP_001732696.1 4195456 D 316385 CDS YP_001732697.1 170083377 6060647 4196276..4197214 1 NC_010473.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4197214 rhaR 6060647 rhaR Escherichia coli str. K-12 substr. DH10B transcriptional activator RhaR YP_001732697.1 4196276 D 316385 CDS YP_001732698.1 170083378 6061304 complement(4197211..4198245) 1 NC_010473.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4198245 rhaT 6061304 rhaT Escherichia coli str. K-12 substr. DH10B rhamnose-proton symporter YP_001732698.1 4197211 R 316385 CDS YP_001732699.1 170083379 6061123 4198530..4199150 1 NC_010473.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4199150 sodA 6061123 sodA Escherichia coli str. K-12 substr. DH10B superoxide dismutase YP_001732699.1 4198530 D 316385 CDS YP_001732700.1 170083380 6061277 4199410..4200393 1 NC_010473.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4200393 kdgT 6061277 kdgT Escherichia coli str. K-12 substr. DH10B 2-keto-3-deoxygluconate permease YP_001732700.1 4199410 D 316385 CDS YP_001732701.1 170083381 6062328 4200542..4201216 1 NC_010473.1 hypothetical protein 4201216 yiiM 6062328 yiiM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732701.1 4200542 D 316385 CDS YP_001732702.1 170083382 6061327 complement(4201322..4202695) 1 NC_010473.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4202695 cpxA 6061327 cpxA Escherichia coli str. K-12 substr. DH10B two-component sensor protein YP_001732702.1 4201322 R 316385 CDS YP_001732703.1 170083383 6060728 complement(4202692..4203390) 1 NC_010473.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4203390 cpxR 6060728 cpxR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator CpxR YP_001732703.1 4202692 R 316385 CDS YP_001732704.1 170083384 6060639 4203540..4204040 1 NC_010473.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4204040 cpxP 6060639 cpxP Escherichia coli str. K-12 substr. DH10B repressor CpxP YP_001732704.1 4203540 D 316385 CDS YP_001732705.1 170083385 6062238 4204189..4205091 1 NC_010473.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4205091 fieF 6062238 fieF Escherichia coli str. K-12 substr. DH10B ferrous iron efflux protein F YP_001732705.1 4204189 D 316385 CDS YP_001732706.1 170083386 6059835 4205272..4206234 1 NC_010473.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4206234 pfkA 6059835 pfkA Escherichia coli str. K-12 substr. DH10B 6-phosphofructokinase YP_001732706.1 4205272 D 316385 CDS YP_001732707.1 170083387 6061263 4206554..4207543 1 NC_010473.1 sulfate transporter subunit 4207543 sbp 6061263 sbp Escherichia coli str. K-12 substr. DH10B sulfate transporter subunit YP_001732707.1 4206554 D 316385 CDS YP_001732708.1 170083388 6060708 4207650..4208405 1 NC_010473.1 CDP-diacylglycerol pyrophosphatase 4208405 cdh 6060708 cdh Escherichia coli str. K-12 substr. DH10B CDP-diacylglycerol pyrophosphatase YP_001732708.1 4207650 D 316385 CDS YP_001732709.1 170083389 6061229 complement(4208460..4209227) 1 NC_010473.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4209227 tpiA 6061229 tpiA Escherichia coli str. K-12 substr. DH10B triosephosphate isomerase YP_001732709.1 4208460 R 316385 CDS YP_001732710.1 170083390 6061212 complement(4209335..4209934) 1 NC_010473.1 hypothetical protein 4209934 yiiQ 6061212 yiiQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732710.1 4209335 R 316385 CDS YP_001732711.1 170083391 6060966 4210035..4210475 1 NC_010473.1 inner membrane protein 4210475 yiiR 6060966 yiiR Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732711.1 4210035 D 316385 CDS YP_001732712.1 170083392 6061911 4210687..4210986 1 NC_010473.1 hypothetical protein 4210986 yiiS 6061911 yiiS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732712.1 4210687 D 316385 CDS YP_001732713.1 170083393 6061952 4211013..4211441 1 NC_010473.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4211441 yiiT 6061952 yiiT Escherichia coli str. K-12 substr. DH10B universal stress protein UspD YP_001732713.1 4211013 D 316385 CDS YP_001732714.1 170083394 6060957 complement(4211446..4212192) 1 NC_010473.1 ferredoxin-NADP reductase 4212192 fpr 6060957 fpr Escherichia coli str. K-12 substr. DH10B ferredoxin-NADP reductase YP_001732714.1 4211446 R 316385 CDS YP_001732715.1 170083395 6061955 complement(4212289..4213299) 1 NC_010473.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4213299 glpX 6061955 glpX Escherichia coli str. K-12 substr. DH10B fructose 1,6-bisphosphatase II YP_001732715.1 4212289 R 316385 CDS YP_001732716.1 170083396 6062224 complement(4213434..4214942) 1 NC_010473.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4214942 glpK 6062224 glpK Escherichia coli str. K-12 substr. DH10B glycerol kinase YP_001732716.1 4213434 R 316385 CDS YP_001732717.1 170083397 6062231 complement(4214965..4215810) 1 NC_010473.1 glycerol facilitator 4215810 glpF 6062231 glpF Escherichia coli str. K-12 substr. DH10B glycerol facilitator YP_001732717.1 4214965 R 316385 CDS YP_001732718.1 170083398 6062237 4216235..4216480 1 NC_010473.1 hypothetical protein 4216480 yiiU 6062237 yiiU Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732718.1 4216235 D 316385 CDS YP_001732719.1 170083399 6061221 complement(4216565..4217050) 1 NC_010473.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4217050 rraA 6061221 rraA Escherichia coli str. K-12 substr. DH10B ribonuclease activity regulator protein RraA YP_001732719.1 4216565 R 316385 CDS YP_001732720.1 170083400 6061090 complement(4217143..4218069) 1 NC_010473.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4218069 menA 6061090 menA Escherichia coli str. K-12 substr. DH10B 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001732720.1 4217143 R 316385 CDS YP_001732721.1 170083401 6061076 complement(4218136..4219467) 1 NC_010473.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4219467 hslU 6061076 hslU Escherichia coli str. K-12 substr. DH10B ATP-dependent protease ATP-binding subunit HslU YP_001732721.1 4218136 R 316385 CDS YP_001732722.1 170083402 6062158 complement(4219477..4220007) 1 NC_010473.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4220007 hslV 6062158 hslV Escherichia coli str. K-12 substr. DH10B ATP-dependent protease peptidase subunit YP_001732722.1 4219477 R 316385 CDS YP_001732723.1 170083403 6060591 complement(4220100..4221059) 1 NC_010473.1 cell division protein FtsN 4221059 ftsN 6060591 ftsN Escherichia coli str. K-12 substr. DH10B cell division protein FtsN YP_001732723.1 4220100 R 316385 CDS YP_001732724.1 170083404 6061022 complement(4221151..4222176) 1 NC_010473.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4222176 cytR 6061022 cytR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator CytR YP_001732724.1 4221151 R 316385 CDS YP_001732725.1 170083405 6061164 complement(4222332..4224530) 1 NC_010473.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4224530 priA 6061164 priA Escherichia coli str. K-12 substr. DH10B primosome assembly protein PriA YP_001732725.1 4222332 R 316385 CDS YP_001732726.1 170083406 6062197 4224733..4224945 1 NC_010473.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4224945 rpmE 6062197 rpmE Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L31 YP_001732726.1 4224733 D 316385 CDS YP_001732727.1 170083407 6060550 complement(4225006..4225614) 1 NC_010473.1 member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase 4225614 yiiX 6060550 yiiX Escherichia coli str. K-12 substr. DH10B putative peptidoglycan peptidase YP_001732727.1 4225006 R 316385 CDS YP_001732728.1 170083408 6061610 complement(4225798..4226115) 1 NC_010473.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4226115 metJ 6061610 metJ Escherichia coli str. K-12 substr. DH10B transcriptional repressor protein MetJ YP_001732728.1 4225798 R 316385 CDS YP_001732729.1 170083409 6061056 4226392..4227552 1 NC_010473.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4227552 metB 6061056 metB Escherichia coli str. K-12 substr. DH10B cystathionine gamma-synthase YP_001732729.1 4226392 D 316385 CDS YP_001732730.1 170083410 6061874 4227555..4229987 1 NC_010473.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4229987 metL 6061874 metL Escherichia coli str. K-12 substr. DH10B bifunctional aspartate kinase II/homoserine dehydrogenase II YP_001732730.1 4227555 D 316385 CDS YP_001732731.1 170083411 6061824 4230336..4231226 1 NC_010473.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4231226 metF 6061824 metF Escherichia coli str. K-12 substr. DH10B 5,10-methylenetetrahydrofolate reductase YP_001732731.1 4230336 D 316385 CDS YP_001732732.1 170083412 6062229 4231555..4233735 1 NC_010473.1 catalase/hydroperoxidase HPI(I) 4233735 katG 6062229 katG Escherichia coli str. K-12 substr. DH10B catalase/hydroperoxidase HPI(I) YP_001732732.1 4231555 D 316385 CDS YP_001732733.1 170083413 6062134 4233828..4234733 1 NC_010473.1 permease 4234733 yijE 6062134 yijE Escherichia coli str. K-12 substr. DH10B permease YP_001732733.1 4233828 D 316385 CDS YP_001732734.1 170083414 6061946 complement(4234760..4235377) 1 NC_010473.1 hypothetical protein 4235377 yijF 6061946 yijF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732734.1 4234760 R 316385 CDS YP_001732735.1 170083415 6058353 complement(4235652..4236755) 1 NC_010473.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4236755 gldA 6058353 gldA Escherichia coli str. K-12 substr. DH10B glycerol dehydrogenase YP_001732735.1 4235652 R 316385 CDS YP_001732736.1 170083416 6058327 complement(4236766..4237428) 1 NC_010473.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4237428 fsaB 6058327 fsaB Escherichia coli str. K-12 substr. DH10B fructose-6-phosphate aldolase YP_001732736.1 4236766 R 316385 CDS YP_001732737.1 170083417 6058379 complement(4237440..4239941) 1 NC_010473.1 fused PTS enzymes: Hpr component; enzyme I component; enzyme IIA component 4239941 ptsA 6058379 ptsA Escherichia coli str. K-12 substr. DH10B fused PTS enzymes: Hpr component; enzyme I component; enzyme IIA component YP_001732737.1 4237440 R 316385 CDS YP_001732738.1 170083418 6058449 4240250..4241329 1 NC_010473.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative fructose-like permease EIIC subunit 2 4241329 frwC 6058449 frwC Escherichia coli str. K-12 substr. DH10B putative fructose-like permease EIIC subunit 2 YP_001732738.1 4240250 D 316385 CDS YP_001732739.1 170083419 6058526 4241344..4241664 1 NC_010473.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB 4241664 frwB 6058526 frwB Escherichia coli str. K-12 substr. DH10B putative PTS system fructose-like transporter subunit EIIB YP_001732739.1 4241344 D 316385 CDS YP_001732740.1 170083420 6058295 4241715..4244012 1 NC_010473.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 4244012 pflD 6058295 pflD Escherichia coli str. K-12 substr. DH10B putative formate acetyltransferase 2 YP_001732740.1 4241715 D 316385 CDS YP_001732741.1 170083421 6058543 4243978..4244856 1 NC_010473.1 pyruvate formate lyase II activase 4244856 pflC 6058543 pflC Escherichia coli str. K-12 substr. DH10B pyruvate formate lyase II activase YP_001732741.1 4243978 D 316385 CDS YP_001732742.1 170083422 6058418 4244858..4245199 1 NC_010473.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative fructose-like phosphotransferase EIIB subunit 3 4245199 frwD 6058418 frwD Escherichia coli str. K-12 substr. DH10B putative fructose-like phosphotransferase EIIB subunit 3 YP_001732742.1 4244858 D 316385 CDS YP_001732743.1 170083423 6058321 complement(4245186..4246037) 1 NC_010473.1 DNA-binding transcriptional regulator 4246037 yijO 6058321 yijO Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001732743.1 4245186 R 316385 CDS YP_001732744.1 170083424 6058376 complement(4246252..4247985) 1 NC_010473.1 hypothetical protein 4247985 yijP 6058376 yijP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732744.1 4246252 R 316385 CDS YP_001732745.1 170083425 6058099 complement(4248167..4250818) 1 NC_010473.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4250818 ppc 6058099 ppc Escherichia coli str. K-12 substr. DH10B phosphoenolpyruvate carboxylase YP_001732745.1 4248167 R 316385 CDS YP_001732746.1 170083426 6058349 complement(4251416..4252567) 1 NC_010473.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4252567 argE 6058349 argE Escherichia coli str. K-12 substr. DH10B acetylornithine deacetylase YP_001732746.1 4251416 R 316385 CDS YP_001732747.1 170083427 6058303 4252721..4253725 1 NC_010473.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4253725 argC 6058303 argC Escherichia coli str. K-12 substr. DH10B N-acetyl-gamma-glutamyl-phosphate reductase YP_001732747.1 4252721 D 316385 CDS YP_001732748.1 170083428 6058363 4253736..4254509 1 NC_010473.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4254509 argB 6058363 argB Escherichia coli str. K-12 substr. DH10B acetylglutamate kinase YP_001732748.1 4253736 D 316385 CDS YP_001732749.1 170083429 6058290 4254570..4255943 1 NC_010473.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4255943 argH 6058290 argH Escherichia coli str. K-12 substr. DH10B argininosuccinate lyase YP_001732749.1 4254570 D 316385 CDS YP_001732750.1 170083430 6062039 4256210..4257127 1 NC_010473.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4257127 oxyR 6062039 oxyR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator OxyR YP_001732750.1 4256210 D 316385 CDS YP_001732751.1 170083431 6058332 complement(4257110..4258510) 1 NC_010473.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4258510 sthA 6058332 sthA Escherichia coli str. K-12 substr. DH10B soluble pyridine nucleotide transhydrogenase YP_001732751.1 4257110 R 316385 CDS YP_001732752.1 170083432 6058525 4258844..4259491 1 NC_010473.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4259491 fabR 6058525 fabR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor FabR YP_001732752.1 4258844 D 316385 CDS YP_001732753.1 170083433 6058266 4259491..4259850 1 NC_010473.1 hypothetical protein 4259850 yijD 6058266 yijD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732753.1 4259491 D 316385 CDS YP_001732754.1 170083434 6062245 complement(4259890..4260990) 1 NC_010473.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4260990 trmA 6062245 trmA Escherichia coli str. K-12 substr. DH10B tRNA (uracil-5-)-methyltransferase YP_001732754.1 4259890 R 316385 CDS YP_001732755.1 170083435 6058457 4261359..4263203 1 NC_010473.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4263203 btuB 6058457 btuB Escherichia coli str. K-12 substr. DH10B vitamin B12/cobalamin outer membrane transporter YP_001732755.1 4261359 D 316385 CDS YP_001732756.1 170083436 6058260 4263148..4264005 1 NC_010473.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4264005 murI 6058260 murI Escherichia coli str. K-12 substr. DH10B glutamate racemase YP_001732756.1 4263148 D 316385 CDS YP_001732757.1 170083437 6061140 4269777..4270805 1 NC_010473.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4270805 murB 6061140 murB Escherichia coli str. K-12 substr. DH10B UDP-N-acetylenolpyruvoylglucosamine reductase YP_001732757.1 4269777 D 316385 CDS YP_001732758.1 170083438 6059190 4270802..4271767 1 NC_010473.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4271767 birA 6059190 birA Escherichia coli str. K-12 substr. DH10B biotin--protein ligase YP_001732758.1 4270802 D 316385 CDS YP_001732759.1 170083439 6059356 complement(4271796..4272746) 1 NC_010473.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4272746 coaA 6059356 coaA Escherichia coli str. K-12 substr. DH10B pantothenate kinase YP_001732759.1 4271796 R 316385 CDS YP_001732760.1 170083440 6058849 4273663..4274847 1 NC_010473.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4274847 tufB 6058849 tufB Escherichia coli str. K-12 substr. DH10B elongation factor Tu YP_001732760.1 4273663 D 316385 CDS YP_001732761.1 170083441 6058921 4275077..4275460 1 NC_010473.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4275460 secE 6058921 secE Escherichia coli str. K-12 substr. DH10B preprotein translocase subunit SecE YP_001732761.1 4275077 D 316385 CDS YP_001732762.1 170083442 6062335 4275462..4276007 1 NC_010473.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4276007 nusG 6062335 nusG Escherichia coli str. K-12 substr. DH10B transcription antitermination protein NusG YP_001732762.1 4275462 D 316385 CDS YP_001732763.1 170083443 6058964 4276166..4276594 1 NC_010473.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4276594 rplK 6058964 rplK Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L11 YP_001732763.1 4276166 D 316385 CDS YP_001732764.1 170083444 6058963 4276598..4277302 1 NC_010473.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4277302 rplA 6058963 rplA Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L1 YP_001732764.1 4276598 D 316385 CDS YP_001732765.1 170083445 6060388 4277715..4278212 1 NC_010473.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4278212 rplJ 6060388 rplJ Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L10 YP_001732765.1 4277715 D 316385 CDS YP_001732766.1 170083446 6059866 4278279..4278644 1 NC_010473.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4278644 rplL 6059866 rplL Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L7/L12 YP_001732766.1 4278279 D 316385 CDS YP_001732767.1 170083447 6058462 4278964..4282992 1 NC_010473.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4282992 rpoB 6058462 rpoB Escherichia coli str. K-12 substr. DH10B DNA-directed RNA polymerase subunit beta YP_001732767.1 4278964 D 316385 CDS YP_001732768.1 170083448 6058956 4283069..4287292 1 NC_010473.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4287292 rpoC 6058956 rpoC Escherichia coli str. K-12 substr. DH10B DNA-directed RNA polymerase subunit beta' YP_001732768.1 4283069 D 316385 CDS YP_001732769.1 170083449 6058386 4287505..4288044 1 NC_010473.1 heat shock protein 4288044 htrC 6058386 htrC Escherichia coli str. K-12 substr. DH10B heat shock protein YP_001732769.1 4287505 D 316385 CDS YP_001732770.1 170083450 6058705 complement(4288454..4289587) 1 NC_010473.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4289587 thiH 6058705 thiH Escherichia coli str. K-12 substr. DH10B thiamine biosynthesis protein ThiH YP_001732770.1 4288454 R 316385 CDS YP_001732771.1 170083451 6058862 complement(4289584..4290354) 1 NC_010473.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4290354 thiG 6058862 thiG Escherichia coli str. K-12 substr. DH10B thiazole synthase YP_001732771.1 4289584 R 316385 CDS YP_001732772.1 170083452 6058905 complement(4290356..4290556) 1 NC_010473.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4290556 thiS 6058905 thiS Escherichia coli str. K-12 substr. DH10B sulfur carrier protein ThiS YP_001732772.1 4290356 R 316385 CDS YP_001732773.1 170083453 6059075 complement(4290540..4291295) 1 NC_010473.1 thiamin (thiazole moiety) biosynthesis protein 4291295 thiF 6059075 thiF Escherichia coli str. K-12 substr. DH10B thiamin (thiazole moiety) biosynthesis protein YP_001732773.1 4290540 R 316385 CDS YP_001732774.1 170083454 6062414 complement(4291288..4291923) 1 NC_010473.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4291923 thiE 6062414 thiE Escherichia coli str. K-12 substr. DH10B thiamine-phosphate pyrophosphorylase YP_001732774.1 4291288 R 316385 CDS YP_001732775.1 170083455 6059259 complement(4291923..4293818) 1 NC_010473.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4293818 thiC 6059259 thiC Escherichia coli str. K-12 substr. DH10B thiamine biosynthesis protein ThiC YP_001732775.1 4291923 R 316385 CDS YP_001732776.1 170083456 6059147 complement(4294051..4294527) 1 NC_010473.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4294527 rsd 6059147 rsd Escherichia coli str. K-12 substr. DH10B anti-RNA polymerase sigma 70 factor YP_001732776.1 4294051 R 316385 CDS YP_001732777.1 170083457 6059900 4294622..4295395 1 NC_010473.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4295395 nudC 6059900 nudC Escherichia coli str. K-12 substr. DH10B NADH pyrophosphatase YP_001732777.1 4294622 D 316385 CDS YP_001732778.1 170083458 6060094 4295435..4296499 1 NC_010473.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4296499 hemE 6060094 hemE Escherichia coli str. K-12 substr. DH10B uroporphyrinogen decarboxylase YP_001732778.1 4295435 D 316385 CDS YP_001732779.1 170083459 6058641 4296509..4297180 1 NC_010473.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4297180 nfi 6058641 nfi Escherichia coli str. K-12 substr. DH10B endonuclease V YP_001732779.1 4296509 D 316385 CDS YP_001732780.1 170083460 6058873 4297223..4297813 1 NC_010473.1 hypothetical protein 4297813 yjaG 6058873 yjaG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732780.1 4297223 D 316385 CDS YP_001732781.1 170083461 6058966 4298000..4298272 1 NC_010473.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4298272 hupA 6058966 hupA Escherichia coli str. K-12 substr. DH10B transcriptional regulator HU subunit alpha YP_001732781.1 4298000 D 316385 CDS YP_001732782.1 170083462 6058981 4298285..4298980 1 NC_010473.1 hypothetical protein 4298980 yjaH 6058981 yjaH Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732782.1 4298285 D 316385 CDS YP_001732783.1 170083463 6058994 complement(4298982..4299407) 1 NC_010473.1 zinc resistance protein 4299407 zraP 6058994 zraP Escherichia coli str. K-12 substr. DH10B zinc resistance protein YP_001732783.1 4298982 R 316385 CDS YP_001732784.1 170083464 6059156 4299645..4301042 1 NC_010473.1 sensor protein ZraS 4301042 zraS 6059156 zraS Escherichia coli str. K-12 substr. DH10B sensor protein ZraS YP_001732784.1 4299645 D 316385 CDS YP_001732785.1 170083465 6059058 4301039..4302364 1 NC_010473.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4302364 zraR 6059058 zraR Escherichia coli str. K-12 substr. DH10B transcriptional regulatory protein ZraR YP_001732785.1 4301039 D 316385 CDS YP_001732786.1 170083466 6059195 complement(4302361..4303650) 1 NC_010473.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4303650 purD 6059195 purD Escherichia coli str. K-12 substr. DH10B phosphoribosylamine--glycine ligase YP_001732786.1 4302361 R 316385 CDS YP_001732787.1 170083467 6059199 complement(4303662..4305251) 1 NC_010473.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4305251 purH 6059199 purH Escherichia coli str. K-12 substr. DH10B bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001732787.1 4303662 R 316385 CDS YP_001732788.1 170083468 6062188 4310953..4311336 1 NC_010473.1 hypothetical protein 4311336 yjaA 6062188 yjaA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732788.1 4310953 D 316385 CDS YP_001732789.1 170083469 6059593 complement(4311399..4311842) 1 NC_010473.1 hypothetical protein 4311842 yjaB 6059593 yjaB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732789.1 4311399 R 316385 CDS YP_001732790.1 170083470 6059662 4311999..4312928 1 NC_010473.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4312928 metA 6059662 metA Escherichia coli str. K-12 substr. DH10B homoserine O-succinyltransferase YP_001732790.1 4311999 D 316385 CDS YP_001732791.1 170083471 6059830 4313197..4314798 1 NC_010473.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4314798 aceB 6059830 aceB Escherichia coli str. K-12 substr. DH10B malate synthase YP_001732791.1 4313197 D 316385 CDS YP_001732792.1 170083472 6060308 4314828..4316132 1 NC_010473.1 isocitrate lyase 4316132 aceA 6060308 aceA Escherichia coli str. K-12 substr. DH10B isocitrate lyase YP_001732792.1 4314828 D 316385 CDS YP_001732793.1 170083473 6060116 4316315..4318051 1 NC_010473.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4318051 aceK 6060116 aceK Escherichia coli str. K-12 substr. DH10B bifunctional isocitrate dehydrogenase kinase/phosphatase protein YP_001732793.1 4316315 D 316385 CDS YP_001732794.1 170083474 6059049 complement(4318020..4320206) 1 NC_010473.1 regulator of acetyl CoA synthetase 4320206 arpA 6059049 arpA Escherichia coli str. K-12 substr. DH10B regulator of acetyl CoA synthetase YP_001732794.1 4318020 R 316385 CDS YP_001732795.1 170083475 6059026 complement(4320523..4321347) 1 NC_010473.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4321347 iclR 6059026 iclR Escherichia coli str. K-12 substr. DH10B IclR family transcriptional regulator YP_001732795.1 4320523 R 316385 CDS YP_001732796.1 170083476 6059383 4321547..4325230 1 NC_010473.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4325230 metH 6059383 metH Escherichia coli str. K-12 substr. DH10B B12-dependent methionine synthase YP_001732796.1 4321547 D 316385 CDS YP_001732797.1 170083477 6059429 4325450..4327081 1 NC_010473.1 transporter 4327081 yjbB 6059429 yjbB Escherichia coli str. K-12 substr. DH10B transporter YP_001732797.1 4325450 D 316385 CDS YP_001732798.1 170083478 6059658 complement(4327172..4327861) 1 NC_010473.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4327861 pepE 6059658 pepE Escherichia coli str. K-12 substr. DH10B peptidase E YP_001732798.1 4327172 R 316385 CDS YP_001732799.1 170083479 6059766 4328073..4328945 1 NC_010473.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4328945 rluF 6059766 rluF Escherichia coli str. K-12 substr. DH10B 23S rRNA pseudouridine synthase F YP_001732799.1 4328073 D 316385 CDS YP_001732800.1 170083480 6060237 complement(4329078..4329350) 1 NC_010473.1 hypothetical protein 4329350 yjbD 6060237 yjbD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732800.1 4329078 R 316385 CDS YP_001732801.1 170083481 6059252 complement(4329603..4330952) 1 NC_010473.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 4330952 lysC 6059252 lysC Escherichia coli str. K-12 substr. DH10B aspartate kinase III YP_001732801.1 4329603 R 316385 CDS YP_001732802.1 170083482 6058820 4331477..4333126 1 NC_010473.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4333126 pgi 6058820 pgi Escherichia coli str. K-12 substr. DH10B glucose-6-phosphate isomerase YP_001732802.1 4331477 D 316385 CDS YP_001732803.1 170083483 6060088 4333625..4333867 1 NC_010473.1 hypothetical protein 4333867 yjbE 6060088 yjbE Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732803.1 4333625 D 316385 CDS YP_001732804.1 170083484 6061808 4333981..4334619 1 NC_010473.1 lipoprotein 4334619 yjbF 6061808 yjbF Escherichia coli str. K-12 substr. DH10B lipoprotein YP_001732804.1 4333981 D 316385 CDS YP_001732805.1 170083485 6061801 4334616..4335353 1 NC_010473.1 hypothetical protein 4335353 yjbG 6061801 yjbG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732805.1 4334616 D 316385 CDS YP_001732806.1 170083486 6061898 4335353..4337449 1 NC_010473.1 porin 4337449 yjbH 6061898 yjbH Escherichia coli str. K-12 substr. DH10B porin YP_001732806.1 4335353 D 316385 CDS YP_001732807.1 170083487 6061725 4338044..4338454 1 NC_010473.1 phosphate-starvation-inducible protein PsiE 4338454 yjbA 6061725 yjbA Escherichia coli str. K-12 substr. DH10B phosphate-starvation-inducible protein PsiE YP_001732807.1 4338044 D 316385 CDS YP_001732808.1 170083488 6060606 complement(4338498..4339973) 1 NC_010473.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 4339973 xylE 6060606 xylE Escherichia coli str. K-12 substr. DH10B D-xylose transporter XylE YP_001732808.1 4338498 R 316385 CDS YP_001732809.1 170083489 6061810 complement(4340345..4341235) 1 NC_010473.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4341235 malG 6061810 malG Escherichia coli str. K-12 substr. DH10B maltose transporter permease YP_001732809.1 4340345 R 316385 CDS YP_001732810.1 170083490 6061812 complement(4341250..4342794) 1 NC_010473.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4342794 malF 6061812 malF Escherichia coli str. K-12 substr. DH10B maltose transporter membrane protein YP_001732810.1 4341250 R 316385 CDS YP_001732811.1 170083491 6060930 complement(4342948..4344138) 1 NC_010473.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4344138 malE 6060930 malE Escherichia coli str. K-12 substr. DH10B maltose ABC transporter periplasmic protein YP_001732811.1 4342948 R 316385 CDS YP_001732812.1 170083492 6060983 4344503..4345618 1 NC_010473.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4345618 malK 6060983 malK Escherichia coli str. K-12 substr. DH10B maltose/maltodextrin transporter ATP-binding protein YP_001732812.1 4344503 D 316385 CDS YP_001732813.1 170083493 6060514 4345690..4347030 1 NC_010473.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4347030 lamB 6060514 lamB Escherichia coli str. K-12 substr. DH10B maltoporin YP_001732813.1 4345690 D 316385 CDS YP_001732814.1 170083494 6062006 4347273..4348193 1 NC_010473.1 maltose regulon periplasmic protein 4348193 malM 6062006 malM Escherichia coli str. K-12 substr. DH10B maltose regulon periplasmic protein YP_001732814.1 4347273 D 316385 CDS YP_001732815.1 170083495 6062014 4348674..4350002 1 NC_010473.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 4350002 yjbI 6062014 yjbI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732815.1 4348674 D 316385 CDS YP_001732816.1 170083496 6061040 4350225..4350722 1 NC_010473.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4350722 ubiC 6061040 ubiC Escherichia coli str. K-12 substr. DH10B chorismate pyruvate lyase YP_001732816.1 4350225 D 316385 CDS YP_001732817.1 170083497 6062055 4350735..4351607 1 NC_010473.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4351607 ubiA 6062055 ubiA Escherichia coli str. K-12 substr. DH10B 4-hydroxybenzoate octaprenyltransferase YP_001732817.1 4350735 D 316385 CDS YP_001732818.1 170083498 6062078 complement(4351762..4354185) 1 NC_010473.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4354185 plsB 6062078 plsB Escherichia coli str. K-12 substr. DH10B glycerol-3-phosphate acyltransferase YP_001732818.1 4351762 R 316385 CDS YP_001732819.1 170083499 6062060 4354356..4354724 1 NC_010473.1 diacylglycerol kinase 4354724 dgkA 6062060 dgkA Escherichia coli str. K-12 substr. DH10B diacylglycerol kinase YP_001732819.1 4354356 D 316385 CDS YP_001732820.1 170083500 6062108 4354834..4355442 1 NC_010473.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4355442 lexA 6062108 lexA Escherichia coli str. K-12 substr. DH10B LexA repressor YP_001732820.1 4354834 D 316385 CDS YP_001732821.1 170083501 6061117 4355461..4356840 1 NC_010473.1 DNA-damage-inducible SOS response protein 4356840 dinF 6061117 dinF Escherichia coli str. K-12 substr. DH10B DNA-damage-inducible SOS response protein YP_001732821.1 4355461 D 316385 CDS YP_001732822.1 170083502 6061130 4356956..4357165 1 NC_010473.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 4357165 yjbJ 6061130 yjbJ Escherichia coli str. K-12 substr. DH10B putative stress-response protein YP_001732822.1 4356956 D 316385 CDS YP_001732823.1 170083503 6062167 complement(4357207..4357722) 1 NC_010473.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4357722 zur 6062167 zur Escherichia coli str. K-12 substr. DH10B zinc uptake transcriptional repressor YP_001732823.1 4357207 R 316385 CDS YP_001732824.1 170083504 6060208 4358040..4358294 1 NC_010473.1 hypothetical protein 4358294 yjbL 6060208 yjbL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732824.1 4358040 D 316385 CDS YP_001732825.1 170083505 6060628 4358318..4359025 1 NC_010473.1 hypothetical protein 4359025 yjbM 6060628 yjbM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732825.1 4358318 D 316385 CDS YP_001732826.1 170083506 6060672 4359388..4360425 1 NC_010473.1 tRNA-dihydrouridine synthase A 4360425 dusA 6060672 dusA Escherichia coli str. K-12 substr. DH10B tRNA-dihydrouridine synthase A YP_001732826.1 4359388 D 316385 CDS YP_001732827.1 170083507 6060706 4360559..4360801 1 NC_010473.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4360801 pspG 6060706 pspG Escherichia coli str. K-12 substr. DH10B phage shock protein G YP_001732827.1 4360559 D 316385 CDS YP_001732828.1 170083508 6059480 complement(4360967..4361950) 1 NC_010473.1 quinone oxidoreductase 4361950 qor 6059480 qor Escherichia coli str. K-12 substr. DH10B quinone oxidoreductase YP_001732828.1 4360967 R 316385 CDS YP_001732829.1 170083509 6059699 4362033..4363448 1 NC_010473.1 unwinds double stranded DNA; replicative DNA helicase 4363448 dnaB 6059699 dnaB Escherichia coli str. K-12 substr. DH10B replicative DNA helicase YP_001732829.1 4362033 D 316385 CDS YP_001732830.1 170083510 6062306 4363501..4364580 1 NC_010473.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4364580 alr 6062306 alr Escherichia coli str. K-12 substr. DH10B alanine racemase YP_001732830.1 4363501 D 316385 CDS YP_001732831.1 170083511 6062235 4364833..4366026 1 NC_010473.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4366026 tyrB 6062235 tyrB Escherichia coli str. K-12 substr. DH10B aromatic amino acid aminotransferase YP_001732831.1 4364833 D 316385 CDS YP_001732832.1 170083512 6060468 4367133..4367846 1 NC_010473.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4367846 aphA 6060468 aphA Escherichia coli str. K-12 substr. DH10B acid phosphatase/phosphotransferase YP_001732832.1 4367133 D 316385 CDS YP_001732833.1 170083513 6062295 4367957..4368373 1 NC_010473.1 hypothetical protein 4368373 yjbQ 6062295 yjbQ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732833.1 4367957 D 316385 CDS YP_001732834.1 170083514 6059764 4368377..4368733 1 NC_010473.1 hypothetical protein 4368733 yjbR 6059764 yjbR Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732834.1 4368377 D 316385 CDS YP_001732835.1 170083515 6059233 4371844..4372380 1 NC_010473.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4372380 ssb 6059233 ssb Escherichia coli str. K-12 substr. DH10B single-stranded DNA-binding protein YP_001732835.1 4371844 D 316385 CDS YP_001732836.1 170083516 6059584 complement(4372479..4372760) 1 NC_010473.1 inner membrane protein 4372760 yjcB 6059584 yjcB Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732836.1 4372479 R 316385 CDS YP_001732837.1 170083517 6059014 complement(4374779..4375102) 1 NC_010473.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4375102 soxS 6059014 soxS Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator SoxS YP_001732837.1 4374779 R 316385 CDS YP_001732838.1 170083518 6059084 4375188..4375652 1 NC_010473.1 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 4375652 soxR 6059084 soxR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing YP_001732838.1 4375188 D 316385 CDS YP_001732839.1 170083519 6059636 4376198..4377547 1 NC_010473.1 permease 4377547 yjcD 6059636 yjcD Escherichia coli str. K-12 substr. DH10B permease YP_001732839.1 4376198 D 316385 CDS YP_001732840.1 170083520 6059218 4377699..4379348 1 NC_010473.1 cation/proton antiporter 4379348 yjcE 6059218 yjcE Escherichia coli str. K-12 substr. DH10B cation/proton antiporter YP_001732840.1 4377699 D 316385 CDS YP_001732841.1 170083521 6059367 complement(4379502..4380794) 1 NC_010473.1 hypothetical protein 4380794 yjcF 6059367 yjcF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732841.1 4379502 R 316385 CDS YP_001732842.1 170083522 6059660 complement(4380972..4382621) 1 NC_010473.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4382621 actP 6059660 actP Escherichia coli str. K-12 substr. DH10B acetate permease YP_001732842.1 4380972 R 316385 CDS YP_001732843.1 170083523 6058972 complement(4382618..4382932) 1 NC_010473.1 inner membrane protein involved in acetate transport 4382932 yjcH 6058972 yjcH Escherichia coli str. K-12 substr. DH10B inner membrane protein involved in acetate transport YP_001732843.1 4382618 R 316385 CDS YP_001732844.1 170083524 6059571 complement(4383132..4385090) 1 NC_010473.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4385090 acs 6059571 acs Escherichia coli str. K-12 substr. DH10B acetyl-CoA synthetase YP_001732844.1 4383132 R 316385 CDS YP_001732845.1 170083525 6060249 4385483..4386919 1 NC_010473.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4386919 nrfA 6060249 nrfA Escherichia coli str. K-12 substr. DH10B cytochrome c552 YP_001732845.1 4385483 D 316385 CDS YP_001732846.1 170083526 6061618 4388304..4388975 1 NC_010473.1 formate-dependent nitrite reductase, 4Fe4S subunit 4388975 nrfC 6061618 nrfC Escherichia coli str. K-12 substr. DH10B formate-dependent nitrite reductase, 4Fe4S subunit YP_001732846.1 4388304 D 316385 CDS YP_001732847.1 170083527 6061467 4388972..4389928 1 NC_010473.1 formate-dependent nitrite reductase, membrane subunit 4389928 nrfD 6061467 nrfD Escherichia coli str. K-12 substr. DH10B formate-dependent nitrite reductase, membrane subunit YP_001732847.1 4388972 D 316385 CDS YP_001732848.1 170083528 6061371 4390008..4391666 1 NC_010473.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4391666 nrfE 6061371 nrfE Escherichia coli str. K-12 substr. DH10B heme lyase subunit NrfE YP_001732848.1 4390008 D 316385 CDS YP_001732849.1 170083529 6062431 4391659..4392042 1 NC_010473.1 formate-dependent nitrite reductase complex subunit NrfF 4392042 nrfF 6062431 nrfF Escherichia coli str. K-12 substr. DH10B formate-dependent nitrite reductase complex subunit NrfF YP_001732849.1 4391659 D 316385 CDS YP_001732850.1 170083530 6061264 4392039..4392635 1 NC_010473.1 formate-dependent nitrite reductase complex subunit NrfG 4392635 nrfG 6061264 nrfG Escherichia coli str. K-12 substr. DH10B formate-dependent nitrite reductase complex subunit NrfG YP_001732850.1 4392039 D 316385 CDS YP_001732851.1 170083531 6061168 4392977..4394290 1 NC_010473.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4394290 gltP 6061168 gltP Escherichia coli str. K-12 substr. DH10B glutamate/aspartate:proton symporter YP_001732851.1 4392977 D 316385 CDS YP_001732852.1 170083532 6060958 complement(4394821..4395510) 1 NC_010473.1 hypothetical protein 4395510 yjcO 6060958 yjcO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732852.1 4394821 R 316385 CDS YP_001732853.1 170083533 6058767 complement(4395604..4397751) 1 NC_010473.1 formate dehydrogenase-H, selenopolypeptide subunit 4397751 fdhF 6058767 fdhF Escherichia coli str. K-12 substr. DH10B formate dehydrogenase-H, selenopolypeptide subunit YP_001732853.1 4395604 R 316385 CDS YP_001732854.1 170083534 6060979 complement(4397949..4399415) 1 NC_010473.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP 4399415 yjcP 6060979 yjcP Escherichia coli str. K-12 substr. DH10B putative outer membrane efflux protein MdtP YP_001732854.1 4397949 R 316385 CDS YP_001732855.1 170083535 6060892 complement(4399412..4401463) 1 NC_010473.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4401463 yjcQ 6060892 yjcQ Escherichia coli str. K-12 substr. DH10B multidrug efflux system protein MdtO YP_001732855.1 4399412 R 316385 CDS YP_001732856.1 170083536 6060791 complement(4401463..4402494) 1 NC_010473.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4402494 yjcR 6060791 yjcR Escherichia coli str. K-12 substr. DH10B multidrug resistance protein MdtN YP_001732856.1 4401463 R 316385 CDS YP_001732857.1 170083537 6060748 complement(4402997..4404982) 1 NC_010473.1 alkyl sulfatase 4404982 yjcS 6060748 yjcS Escherichia coli str. K-12 substr. DH10B alkyl sulfatase YP_001732857.1 4402997 R 316385 CDS YP_001732858.1 170083538 6059889 complement(4405255..4406184) 1 NC_010473.1 D-allose kinase 4406184 alsK 6059889 alsK Escherichia coli str. K-12 substr. DH10B D-allose kinase YP_001732858.1 4405255 R 316385 CDS YP_001732859.1 170083539 6060001 complement(4406168..4406863) 1 NC_010473.1 allulose-6-phosphate 3-epimerase 4406863 alsE 6060001 alsE Escherichia coli str. K-12 substr. DH10B allulose-6-phosphate 3-epimerase YP_001732859.1 4406168 R 316385 CDS YP_001732860.1 170083540 6060392 complement(4406874..4407854) 1 NC_010473.1 D-allose transporter subunit 4407854 alsC 6060392 alsC Escherichia coli str. K-12 substr. DH10B D-allose transporter subunit YP_001732860.1 4406874 R 316385 CDS YP_001732861.1 170083541 6062206 complement(4407833..4409365) 1 NC_010473.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4409365 alsA 6062206 alsA Escherichia coli str. K-12 substr. DH10B D-allose transporter ATP-binding protein YP_001732861.1 4407833 R 316385 CDS YP_001732862.1 170083542 6059111 complement(4409492..4410427) 1 NC_010473.1 D-allose transporter subunit 4410427 alsB 6059111 alsB Escherichia coli str. K-12 substr. DH10B D-allose transporter subunit YP_001732862.1 4409492 R 316385 CDS YP_001732863.1 170083543 6059487 complement(4410486..4411376) 1 NC_010473.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4411376 rpiR 6059487 rpiR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor RpiR YP_001732863.1 4410486 R 316385 CDS YP_001732864.1 170083544 6059494 4411735..4412184 1 NC_010473.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4412184 rpiB 6059494 rpiB Escherichia coli str. K-12 substr. DH10B ribose-5-phosphate isomerase B YP_001732864.1 4411735 D 316385 CDS YP_001732865.1 170083545 6059547 4412253..4412582 1 NC_010473.1 hypothetical protein 4412582 yjdP 6059547 yjdP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732865.1 4412253 D 316385 CDS YP_001732866.1 170083546 6059574 complement(4412729..4413487) 1 NC_010473.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4413487 phnP 6059574 phnP Escherichia coli str. K-12 substr. DH10B carbon-phosphorus lyase complex accessory protein YP_001732866.1 4412729 R 316385 CDS YP_001732867.1 170083547 6059625 complement(4413489..4413923) 1 NC_010473.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4413923 phnO 6059625 phnO Escherichia coli str. K-12 substr. DH10B aminoalkylphosphonic acid N-acetyltransferase YP_001732867.1 4413489 R 316385 CDS YP_001732868.1 170083548 6059741 complement(4413910..4414467) 1 NC_010473.1 ribose 1,5-bisphosphokinase 4414467 phnN 6059741 phnN Escherichia coli str. K-12 substr. DH10B ribose 1,5-bisphosphokinase YP_001732868.1 4413910 R 316385 CDS YP_001732869.1 170083549 6059748 complement(4414467..4415603) 1 NC_010473.1 carbon-phosphorus lyase complex subunit 4415603 phnM 6059748 phnM Escherichia coli str. K-12 substr. DH10B carbon-phosphorus lyase complex subunit YP_001732869.1 4414467 R 316385 CDS YP_001732870.1 170083550 6059729 complement(4415600..4416280) 1 NC_010473.1 carbon-phosphorus lyase complex subunit 4416280 phnL 6059729 phnL Escherichia coli str. K-12 substr. DH10B carbon-phosphorus lyase complex subunit YP_001732870.1 4415600 R 316385 CDS YP_001732871.1 170083551 6059761 complement(4416391..4417149) 1 NC_010473.1 phosphonate C-P lyase system protein PhnK 4417149 phnK 6059761 phnK Escherichia coli str. K-12 substr. DH10B phosphonate C-P lyase system protein PhnK YP_001732871.1 4416391 R 316385 CDS YP_001732872.1 170083552 6059906 complement(4417146..4417991) 1 NC_010473.1 carbon-phosphorus lyase complex subunit 4417991 phnJ 6059906 phnJ Escherichia coli str. K-12 substr. DH10B carbon-phosphorus lyase complex subunit YP_001732872.1 4417146 R 316385 CDS YP_001732873.1 170083553 6059965 complement(4417984..4419048) 1 NC_010473.1 carbon-phosphorus lyase complex subunit 4419048 phnI 6059965 phnI Escherichia coli str. K-12 substr. DH10B carbon-phosphorus lyase complex subunit YP_001732873.1 4417984 R 316385 CDS YP_001732874.1 170083554 6059834 complement(4419048..4419632) 1 NC_010473.1 carbon-phosphorus lyase complex subunit 4419632 phnH 6059834 phnH Escherichia coli str. K-12 substr. DH10B carbon-phosphorus lyase complex subunit YP_001732874.1 4419048 R 316385 CDS YP_001732875.1 170083555 6059892 complement(4419629..4420081) 1 NC_010473.1 carbon-phosphorus lyase complex subunit 4420081 phnG 6059892 phnG Escherichia coli str. K-12 substr. DH10B carbon-phosphorus lyase complex subunit YP_001732875.1 4419629 R 316385 CDS YP_001732876.1 170083556 6060302 complement(4420082..4420807) 1 NC_010473.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4420807 phnF 6060302 phnF Escherichia coli str. K-12 substr. DH10B phosphonate metabolism transcriptional regulator PhnF YP_001732876.1 4420082 R 316385 CDS YP_001732877.1 170083557 6060449 complement(4421721..4422737) 1 NC_010473.1 phosphonate/organophosphate ester ABC transporter periplasmic-binding protein 4422737 phnD 6060449 phnD Escherichia coli str. K-12 substr. DH10B phosphonate/organophosphate ester ABC transporter periplasmic-binding protein YP_001732877.1 4421721 R 316385 CDS YP_001732878.1 170083558 6058189 complement(4422762..4423550) 1 NC_010473.1 phosphonate/organophosphate ester transporter subunit 4423550 phnC 6058189 phnC Escherichia coli str. K-12 substr. DH10B phosphonate/organophosphate ester transporter subunit YP_001732878.1 4422762 R 316385 CDS YP_001732879.1 170083559 6058654 complement(4423683..4424126) 1 NC_010473.1 hypothetical protein 4424126 phnB 6058654 phnB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732879.1 4423683 R 316385 CDS YP_001732880.1 170083560 6058665 complement(4424784..4425119) 1 NC_010473.1 hypothetical protein 4425119 phnA 6058665 phnA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732880.1 4424784 R 316385 CDS YP_001732881.1 170083561 6062392 4425520..4427748 1 NC_010473.1 hypothetical protein 4427748 yjdA 6062392 yjdA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732881.1 4425520 D 316385 CDS YP_001732882.1 170083562 6062291 4427745..4428623 1 NC_010473.1 hypothetical protein 4428623 yjcZ 6062291 yjcZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732882.1 4427745 D 316385 CDS YP_001732883.1 170083563 6062147 4428887..4430389 1 NC_010473.1 proline/glycine betaine transporter 4430389 proP 6062147 proP Escherichia coli str. K-12 substr. DH10B proline/glycine betaine transporter YP_001732883.1 4428887 D 316385 CDS YP_001732884.1 170083564 6062157 complement(4430566..4431657) 1 NC_010473.1 sensor protein BasS/PmrB 4431657 basS 6062157 basS Escherichia coli str. K-12 substr. DH10B sensor protein BasS/PmrB YP_001732884.1 4430566 R 316385 CDS YP_001732885.1 170083565 6062068 complement(4431667..4432335) 1 NC_010473.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4432335 basR 6062068 basR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator BasR YP_001732885.1 4431667 R 316385 CDS YP_001732886.1 170083566 6061998 complement(4432332..4433975) 1 NC_010473.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein 4433975 eptA 6061998 eptA Escherichia coli str. K-12 substr. DH10B putative cell division protein YP_001732886.1 4432332 R 316385 CDS YP_001732887.1 170083567 6062040 complement(4434079..4435416) 1 NC_010473.1 arginine:agmatin antiporter 4435416 adiC 6062040 adiC Escherichia coli str. K-12 substr. DH10B arginine:agmatin antiporter YP_001732887.1 4434079 R 316385 CDS YP_001732888.1 170083568 6062023 complement(4439105..4440013) 1 NC_010473.1 DNA-binding transcriptional regulator MelR 4440013 melR 6062023 melR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator MelR YP_001732888.1 4439105 R 316385 CDS YP_001732889.1 170083569 6061993 4440296..4441651 1 NC_010473.1 alpha-galactosidase, NAD(P)-binding 4441651 melA 6061993 melA Escherichia coli str. K-12 substr. DH10B alpha-galactosidase, NAD(P)-binding YP_001732889.1 4440296 D 316385 CDS YP_001732890.1 170083570 6061981 4441766..4443175 1 NC_010473.1 melibiose:sodium symporter 4443175 melB 6061981 melB Escherichia coli str. K-12 substr. DH10B melibiose:sodium symporter YP_001732890.1 4441766 D 316385 CDS YP_001732891.1 170083571 6061979 complement(4443314..4443943) 1 NC_010473.1 hypothetical protein 4443943 yjdF 6061979 yjdF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732891.1 4443314 R 316385 CDS YP_001732892.1 170083572 6061932 complement(4444065..4445711) 1 NC_010473.1 anaerobic class I fumarate hydratase 4445711 fumB 6061932 fumB Escherichia coli str. K-12 substr. DH10B anaerobic class I fumarate hydratase YP_001732892.1 4444065 R 316385 CDS YP_001732893.1 170083573 6061959 complement(4445789..4447129) 1 NC_010473.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4447129 dcuB 6061959 dcuB Escherichia coli str. K-12 substr. DH10B anaerobic C4-dicarboxylate transporter YP_001732893.1 4445789 R 316385 CDS YP_001732894.1 170083574 6061948 complement(4448416..4450047) 1 NC_010473.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4450047 dcuS 6061948 dcuS Escherichia coli str. K-12 substr. DH10B sensory histidine kinase DcuS YP_001732894.1 4448416 R 316385 CDS YP_001732895.1 170083575 6061943 4450228..4450458 1 NC_010473.1 hypothetical protein 4450458 yjdI 6061943 yjdI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732895.1 4450228 D 316385 CDS YP_001732896.1 170083576 6061944 4450470..4450742 1 NC_010473.1 acyltransferase 4450742 yjdJ 6061944 yjdJ Escherichia coli str. K-12 substr. DH10B acyltransferase YP_001732896.1 4450470 D 316385 CDS YP_001732897.1 170083577 6061935 4450969..4451265 1 NC_010473.1 hypothetical protein 4451265 yjdK 6061935 yjdK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732897.1 4450969 D 316385 CDS YP_001732898.1 170083578 6061938 4451293..4451466 1 NC_010473.1 hypothetical protein 4451466 yjdO 6061938 yjdO Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732898.1 4451293 D 316385 CDS YP_001732899.1 170083579 6061871 complement(4451585..4453102) 1 NC_010473.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4453102 lysU 6061871 lysU Escherichia coli str. K-12 substr. DH10B lysyl-tRNA synthetase YP_001732899.1 4451585 R 316385 CDS YP_001732900.1 170083580 6061891 complement(4453339..4454796) 1 NC_010473.1 transporter 4454796 yjdL 6061891 yjdL Escherichia coli str. K-12 substr. DH10B transporter YP_001732900.1 4453339 R 316385 CDS YP_001732901.1 170083581 6061887 complement(4454855..4457002) 1 NC_010473.1 lysine decarboxylase 1 4457002 cadA 6061887 cadA Escherichia coli str. K-12 substr. DH10B lysine decarboxylase 1 YP_001732901.1 4454855 R 316385 CDS YP_001732902.1 170083582 6061764 complement(4457082..4458416) 1 NC_010473.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4458416 cadB 6061764 cadB Escherichia coli str. K-12 substr. DH10B lysine/cadaverine antiporter YP_001732902.1 4457082 R 316385 CDS YP_001732903.1 170083583 6061742 complement(4458781..4460319) 1 NC_010473.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4460319 cadC 6061742 cadC Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator CadC YP_001732903.1 4458781 R 316385 CDS YP_001732904.1 170083584 6059677 complement(4461118..4461693) 1 NC_010473.1 putative transcriptional regulator 4461693 yjdC 6059677 yjdC Escherichia coli str. K-12 substr. DH10B putative transcriptional regulator YP_001732904.1 4461118 R 316385 CDS YP_001732905.1 170083585 6061698 complement(4461730..4463427) 1 NC_010473.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4463427 dipZ 6061698 dipZ Escherichia coli str. K-12 substr. DH10B thiol:disulfide interchange protein YP_001732905.1 4461730 R 316385 CDS YP_001732906.1 170083586 6061659 complement(4463403..4463741) 1 NC_010473.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4463741 cutA 6061659 cutA Escherichia coli str. K-12 substr. DH10B divalent-cation tolerance protein CutA YP_001732906.1 4463403 R 316385 CDS YP_001732907.1 170083587 6061642 complement(4463857..4465158) 1 NC_010473.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4465158 dcuA 6061642 dcuA Escherichia coli str. K-12 substr. DH10B anaerobic C4-dicarboxylate transporter YP_001732907.1 4463857 R 316385 CDS YP_001732908.1 170083588 6061587 complement(4465276..4466712) 1 NC_010473.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4466712 aspA 6061587 aspA Escherichia coli str. K-12 substr. DH10B aspartate ammonia-lyase YP_001732908.1 4465276 R 316385 CDS YP_001732909.1 170083589 6061492 4467049..4467525 1 NC_010473.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4467525 fxsA 6061492 fxsA Escherichia coli str. K-12 substr. DH10B FxsA protein YP_001732909.1 4467049 D 316385 CDS YP_001732910.1 170083590 6061385 complement(4467541..4468797) 1 NC_010473.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 4468797 yjeH 6061385 yjeH Escherichia coli str. K-12 substr. DH10B inner membrane protein YjeH YP_001732910.1 4467541 R 316385 CDS YP_001732911.1 170083591 6061370 4469073..4469366 1 NC_010473.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4469366 groES 6061370 groES Escherichia coli str. K-12 substr. DH10B co-chaperonin GroES YP_001732911.1 4469073 D 316385 CDS YP_001732912.1 170083592 6061450 4469410..4471056 1 NC_010473.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4471056 groEL 6061450 groEL Escherichia coli str. K-12 substr. DH10B chaperonin GroEL YP_001732912.1 4469410 D 316385 CDS YP_001732913.1 170083593 6061415 4471194..4471547 1 NC_010473.1 hypothetical protein 4471547 yjeI 6061415 yjeI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732913.1 4471194 D 316385 CDS YP_001732914.1 170083594 6061428 complement(4471750..4472619) 1 NC_010473.1 hypothetical protein 4472619 yjeJ 6061428 yjeJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732914.1 4471750 R 316385 CDS YP_001732915.1 170083595 6061410 4474084..4474650 1 NC_010473.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4474650 efp 6061410 efp Escherichia coli str. K-12 substr. DH10B elongation factor P YP_001732915.1 4474084 D 316385 CDS YP_001732916.1 170083596 6061249 4474702..4474827 1 NC_010473.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4474827 ecnA 6061249 ecnA Escherichia coli str. K-12 substr. DH10B entericidin A YP_001732916.1 4474702 D 316385 CDS YP_001732917.1 170083597 6061240 4474938..4475084 1 NC_010473.1 entericidin B membrane lipoprotein 4475084 ecnB 6061240 ecnB Escherichia coli str. K-12 substr. DH10B entericidin B membrane lipoprotein YP_001732917.1 4474938 D 316385 CDS YP_001732918.1 170083598 6061330 4475260..4475577 1 NC_010473.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4475577 sugE 6061330 sugE Escherichia coli str. K-12 substr. DH10B quaternary ammonium compound-resistance protein SugE YP_001732918.1 4475260 D 316385 CDS YP_001732919.1 170083599 6061284 complement(4475574..4476107) 1 NC_010473.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4476107 blc 6061284 blc Escherichia coli str. K-12 substr. DH10B outer membrane lipoprotein Blc YP_001732919.1 4475574 R 316385 CDS YP_001732920.1 170083600 6061224 complement(4476196..4477329) 1 NC_010473.1 beta-lactamase 4477329 ampC 6061224 ampC Escherichia coli str. K-12 substr. DH10B beta-lactamase YP_001732920.1 4476196 R 316385 CDS YP_001732921.1 170083601 6061190 complement(4477392..4477751) 1 NC_010473.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4477751 frdD 6061190 frdD Escherichia coli str. K-12 substr. DH10B fumarate reductase subunit D YP_001732921.1 4477392 R 316385 CDS YP_001732922.1 170083602 6061148 complement(4477762..4478157) 1 NC_010473.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4478157 frdC 6061148 frdC Escherichia coli str. K-12 substr. DH10B fumarate reductase subunit C YP_001732922.1 4477762 R 316385 CDS YP_001732923.1 170083603 6061106 complement(4478895..4480703) 1 NC_010473.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4480703 frdA 6061106 frdA Escherichia coli str. K-12 substr. DH10B fumarate reductase flavoprotein subunit YP_001732923.1 4478895 R 316385 CDS YP_001732924.1 170083604 6061093 4481028..4482005 1 NC_010473.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4482005 poxA 6061093 poxA Escherichia coli str. K-12 substr. DH10B lysyl-tRNA synthetase YP_001732924.1 4481028 D 316385 CDS YP_001732925.1 170083605 6061086 4482224..4483726 1 NC_010473.1 transporter 4483726 yjeM 6061086 yjeM Escherichia coli str. K-12 substr. DH10B transporter YP_001732925.1 4482224 D 316385 CDS YP_001732926.1 170083606 6061083 4483778..4484092 1 NC_010473.1 hypothetical protein 4484092 yjeN 6061083 yjeN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732926.1 4483778 D 316385 CDS YP_001732927.1 170083607 6061050 4484089..4484403 1 NC_010473.1 inner membrane protein 4484403 yjeO 6061050 yjeO Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732927.1 4484089 D 316385 CDS YP_001732928.1 170083608 6060997 complement(4484432..4487755) 1 NC_010473.1 hypothetical protein 4487755 yjeP 6060997 yjeP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732928.1 4484432 R 316385 CDS YP_001732929.1 170083609 6060679 complement(4487777..4488745) 1 NC_010473.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4488745 psd 6060679 psd Escherichia coli str. K-12 substr. DH10B phosphatidylserine decarboxylase YP_001732929.1 4487777 R 316385 CDS YP_001732930.1 170083610 6060835 complement(4488842..4489894) 1 NC_010473.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4489894 rsgA 6060835 rsgA Escherichia coli str. K-12 substr. DH10B ribosome-associated GTPase YP_001732930.1 4488842 R 316385 CDS YP_001732931.1 170083611 6060787 4489989..4490534 1 NC_010473.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4490534 orn 6060787 orn Escherichia coli str. K-12 substr. DH10B oligoribonuclease YP_001732931.1 4489989 D 316385 CDS YP_001732932.1 170083612 6059773 complement(4491313..4492452) 1 NC_010473.1 Fe-S electron transport protein 4492452 yjeS 6059773 yjeS Escherichia coli str. K-12 substr. DH10B Fe-S electron transport protein YP_001732932.1 4491313 R 316385 CDS YP_001732933.1 170083613 6062342 4492451..4493998 1 NC_010473.1 hypothetical protein 4493998 yjeF 6062342 yjeF Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732933.1 4492451 D 316385 CDS YP_001732934.1 170083614 6062372 4493970..4494431 1 NC_010473.1 possibly involved in cell wall synthesis; putative ATPase 4494431 yjeE 6062372 yjeE Escherichia coli str. K-12 substr. DH10B putative ATPase YP_001732934.1 4493970 D 316385 CDS YP_001732935.1 170083615 6062112 4494450..4495787 1 NC_010473.1 N-acetylmuramoyl-l-alanine amidase II 4495787 amiB 6062112 amiB Escherichia coli str. K-12 substr. DH10B N-acetylmuramoyl-l-alanine amidase II YP_001732935.1 4494450 D 316385 CDS YP_001732936.1 170083616 6062265 4495797..4497644 1 NC_010473.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4497644 mutL 6062265 mutL Escherichia coli str. K-12 substr. DH10B DNA mismatch repair protein YP_001732936.1 4495797 D 316385 CDS YP_001732937.1 170083617 6058647 4497637..4498587 1 NC_010473.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4498587 miaA 6058647 miaA Escherichia coli str. K-12 substr. DH10B tRNA delta(2)-isopentenylpyrophosphate transferase YP_001732937.1 4497637 D 316385 CDS YP_001732938.1 170083618 6059274 4498673..4498981 1 NC_010473.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4498981 hfq 6059274 hfq Escherichia coli str. K-12 substr. DH10B RNA-binding protein Hfq YP_001732938.1 4498673 D 316385 CDS YP_001732939.1 170083619 6062200 4499057..4500337 1 NC_010473.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 4500337 hflX 6062200 hflX Escherichia coli str. K-12 substr. DH10B putative GTPase HflX YP_001732939.1 4499057 D 316385 CDS YP_001732940.1 170083620 6060766 4500423..4501682 1 NC_010473.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4501682 hflK 6060766 hflK Escherichia coli str. K-12 substr. DH10B FtsH protease regulator HflK YP_001732940.1 4500423 D 316385 CDS YP_001732941.1 170083621 6058965 4501685..4502689 1 NC_010473.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4502689 hflC 6058965 hflC Escherichia coli str. K-12 substr. DH10B FtsH protease regulator HflC YP_001732941.1 4501685 D 316385 CDS YP_001732942.1 170083622 6058882 4502771..4502968 1 NC_010473.1 inner membrane protein 4502968 yjeT 6058882 yjeT Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732942.1 4502771 D 316385 CDS YP_001732943.1 170083623 6058928 4503072..4504370 1 NC_010473.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4504370 purA 6058928 purA Escherichia coli str. K-12 substr. DH10B adenylosuccinate synthetase YP_001732943.1 4503072 D 316385 CDS YP_001732944.1 170083624 6060699 4504575..4505000 1 NC_010473.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4505000 nsrR 6060699 nsrR Escherichia coli str. K-12 substr. DH10B transcriptional repressor NsrR YP_001732944.1 4504575 D 316385 CDS YP_001732945.1 170083625 6060537 4505039..4507480 1 NC_010473.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4507480 rnr 6060537 rnr Escherichia coli str. K-12 substr. DH10B exoribonuclease R YP_001732945.1 4505039 D 316385 CDS YP_001732946.1 170083626 6060608 4507660..4508391 1 NC_010473.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4508391 rlmB 6060608 rlmB Escherichia coli str. K-12 substr. DH10B 23S rRNA (guanosine-2'-O-)-methyltransferase YP_001732946.1 4507660 D 316385 CDS YP_001732947.1 170083627 6060183 4508518..4508919 1 NC_010473.1 hypothetical protein 4508919 yjfI 6060183 yjfI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732947.1 4508518 D 316385 CDS YP_001732948.1 170083628 6062096 4508938..4509636 1 NC_010473.1 transcriptional regulator effector protein 4509636 yjfJ 6062096 yjfJ Escherichia coli str. K-12 substr. DH10B transcriptional regulator effector protein YP_001732948.1 4508938 D 316385 CDS YP_001732949.1 170083629 6062141 4509687..4510346 1 NC_010473.1 hypothetical protein 4510346 yjfK 6062141 yjfK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732949.1 4509687 D 316385 CDS YP_001732950.1 170083630 6060654 4510364..4510762 1 NC_010473.1 inner membrane protein 4510762 yjfL 6060654 yjfL Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732950.1 4510364 D 316385 CDS YP_001732951.1 170083631 6060990 4510772..4511410 1 NC_010473.1 hypothetical protein 4511410 yjfM 6060990 yjfM Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732951.1 4510772 D 316385 CDS YP_001732952.1 170083632 6060558 4511413..4512576 1 NC_010473.1 synthetase/amidase 4512576 yjfC 6060558 yjfC Escherichia coli str. K-12 substr. DH10B synthetase/amidase YP_001732952.1 4511413 D 316385 CDS YP_001732953.1 170083633 6062061 4512660..4514285 1 NC_010473.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4514285 aidB 6062061 aidB Escherichia coli str. K-12 substr. DH10B isovaleryl CoA dehydrogenase YP_001732953.1 4512660 D 316385 CDS YP_001732954.1 170083634 6062021 complement(4514402..4514677) 1 NC_010473.1 hypothetical protein 4514677 yjfN 6062021 yjfN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732954.1 4514402 R 316385 CDS YP_001732955.1 170083635 6061976 complement(4514826..4515155) 1 NC_010473.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A 4515155 yjfO 6061976 yjfO Escherichia coli str. K-12 substr. DH10B putative biofilm stress and motility protein A YP_001732955.1 4514826 R 316385 CDS YP_001732956.1 170083636 6061014 4515337..4516086 1 NC_010473.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4516086 yjfP 6061014 yjfP Escherichia coli str. K-12 substr. DH10B esterase YP_001732956.1 4515337 D 316385 CDS YP_001732957.1 170083637 6061962 complement(4516083..4516838) 1 NC_010473.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4516838 ulaR 6061962 ulaR Escherichia coli str. K-12 substr. DH10B transcriptional repressor UlaR YP_001732957.1 4516083 R 316385 CDS YP_001732958.1 170083638 6061937 complement(4516946..4518010) 1 NC_010473.1 putative L-ascorbate 6-phosphate lactonase 4518010 ulaG 6061937 ulaG Escherichia coli str. K-12 substr. DH10B putative L-ascorbate 6-phosphate lactonase YP_001732958.1 4516946 R 316385 CDS YP_001732959.1 170083639 6060975 4518365..4519762 1 NC_010473.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4519762 ulaA 6060975 ulaA Escherichia coli str. K-12 substr. DH10B PTS system ascorbate-specific transporter subunit IIC YP_001732959.1 4518365 D 316385 CDS YP_001732960.1 170083640 6059686 4519778..4520083 1 NC_010473.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4520083 ulaB 6059686 ulaB Escherichia coli str. K-12 substr. DH10B PTS system L-ascorbate-specific transporter subunit IIB YP_001732960.1 4519778 D 316385 CDS YP_001732961.1 170083641 6061895 4520093..4520557 1 NC_010473.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4520557 ulaC 6061895 ulaC Escherichia coli str. K-12 substr. DH10B PTS system L-ascorbate-specific transporter subunit IIA YP_001732961.1 4520093 D 316385 CDS YP_001732962.1 170083642 6061918 4520571..4521221 1 NC_010473.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4521221 ulaD 6061918 ulaD Escherichia coli str. K-12 substr. DH10B 3-keto-L-gulonate-6-phosphate decarboxylase YP_001732962.1 4520571 D 316385 CDS YP_001732963.1 170083643 6061777 4521231..4522085 1 NC_010473.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4522085 ulaE 6061777 ulaE Escherichia coli str. K-12 substr. DH10B L-xylulose 5-phosphate 3-epimerase YP_001732963.1 4521231 D 316385 CDS YP_001732964.1 170083644 6060928 4522085..4522771 1 NC_010473.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4522771 sgaE 6060928 sgaE Escherichia coli str. K-12 substr. DH10B L-ribulose-5-phosphate 4-epimerase YP_001732964.1 4522085 D 316385 CDS YP_001732965.1 170083645 6060926 complement(4522901..4523176) 1 NC_010473.1 hypothetical protein 4523176 yjfY 6060926 yjfY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732965.1 4522901 R 316385 CDS YP_001732966.1 170083646 6061865 4523503..4523898 1 NC_010473.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4523898 rpsF 6061865 rpsF Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S6 YP_001732966.1 4523503 D 316385 CDS YP_001732967.1 170083647 6061803 4524224..4524451 1 NC_010473.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4524451 rpsR 6061803 rpsR Escherichia coli str. K-12 substr. DH10B 30S ribosomal protein S18 YP_001732967.1 4524224 D 316385 CDS YP_001732968.1 170083648 6061787 4524493..4524942 1 NC_010473.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4524942 rplI 6061787 rplI Escherichia coli str. K-12 substr. DH10B 50S ribosomal protein L9 YP_001732968.1 4524493 D 316385 CDS YP_001732969.1 170083649 6060589 complement(4525013..4525807) 1 NC_010473.1 hypothetical protein 4525807 yjfZ 6060589 yjfZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732969.1 4525013 R 316385 CDS YP_001732970.1 170083650 6061723 4526154..4526480 1 NC_010473.1 transcriptional regulator 4526480 ytfA 6061723 ytfA Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001732970.1 4526154 D 316385 CDS YP_001732971.1 170083651 6061705 complement(4526464..4527102) 1 NC_010473.1 cell envelope opacity-associated protein 4527102 ytfB 6061705 ytfB Escherichia coli str. K-12 substr. DH10B cell envelope opacity-associated protein YP_001732971.1 4526464 R 316385 CDS YP_001732972.1 170083652 6061716 4527320..4527940 1 NC_010473.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4527940 fklB 6061716 fklB Escherichia coli str. K-12 substr. DH10B peptidyl-prolyl cis-trans isomerase YP_001732972.1 4527320 D 316385 CDS YP_001732973.1 170083653 6059485 4528249..4529661 1 NC_010473.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4529661 cycA 6059485 cycA Escherichia coli str. K-12 substr. DH10B D-alanine/D-serine/glycine permease YP_001732973.1 4528249 D 316385 CDS YP_001732974.1 170083654 6060842 complement(4529706..4530368) 1 NC_010473.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4530368 ytfE 6060842 ytfE Escherichia coli str. K-12 substr. DH10B iron-sulfur cluster repair di-iron protein YP_001732974.1 4529706 R 316385 CDS YP_001732975.1 170083655 6061658 complement(4530476..4531450) 1 NC_010473.1 inner membrane protein 4531450 ytfF 6061658 ytfF Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732975.1 4530476 R 316385 CDS YP_001732976.1 170083656 6061688 complement(4531549..4532409) 1 NC_010473.1 NAD(P)H:quinone oxidoreductase 4532409 ytfG 6061688 ytfG Escherichia coli str. K-12 substr. DH10B NAD(P)H:quinone oxidoreductase YP_001732976.1 4531549 R 316385 CDS YP_001732977.1 170083657 6058626 4532498..4532878 1 NC_010473.1 transcriptional regulator 4532878 ytfH 6058626 ytfH Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001732977.1 4532498 D 316385 CDS YP_001732978.1 170083658 6061645 complement(4533007..4534950) 1 NC_010473.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4534950 cpdB 6061645 cpdB Escherichia coli str. K-12 substr. DH10B bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_001732978.1 4533007 R 316385 CDS YP_001732979.1 170083659 6060817 4536092..4537030 1 NC_010473.1 hypothetical protein 4537030 ytfI 6060817 ytfI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732979.1 4536092 D 316385 CDS YP_001732980.1 170083660 6061559 complement(4537093..4537647) 1 NC_010473.1 transcriptional regulator 4537647 ytfJ 6061559 ytfJ Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001732980.1 4537093 R 316385 CDS YP_001732981.1 170083661 6060670 4537972..4538178 1 NC_010473.1 hypothetical protein 4538178 ytfK 6060670 ytfK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732981.1 4537972 D 316385 CDS YP_001732982.1 170083662 6061543 complement(4538257..4539600) 1 NC_010473.1 inner membrane protein 4539600 ytfL 6061543 ytfL Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001732982.1 4538257 R 316385 CDS YP_001732983.1 170083663 6061530 complement(4539923..4540561) 1 NC_010473.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4540561 msrA 6061530 msrA Escherichia coli str. K-12 substr. DH10B methionine sulfoxide reductase A YP_001732983.1 4539923 R 316385 CDS YP_001732984.1 170083664 6061419 4540767..4542500 1 NC_010473.1 outer membrane protein 4542500 ytfM 6061419 ytfM Escherichia coli str. K-12 substr. DH10B outer membrane protein YP_001732984.1 4540767 D 316385 CDS YP_001732985.1 170083665 6061447 4542497..4546276 1 NC_010473.1 hypothetical protein 4546276 ytfN 6061447 ytfN Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732985.1 4542497 D 316385 CDS YP_001732986.1 170083666 6061421 4546279..4546620 1 NC_010473.1 hypothetical protein 4546620 ytfP 6061421 ytfP Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732986.1 4546279 D 316385 CDS YP_001732987.1 170083667 6061416 complement(4546361..4546630) 1 NC_010473.1 hypothetical protein 4546630 yzfA 6061416 yzfA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732987.1 4546361 R 316385 CDS YP_001732988.1 170083668 6061430 4546832..4547083 1 NC_010473.1 part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 4547083 chpS 6061430 chpS Escherichia coli str. K-12 substr. DH10B antitoxin ChpS YP_001732988.1 4546832 D 316385 CDS YP_001732989.1 170083669 6061387 4547077..4547427 1 NC_010473.1 toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 4547427 chpB 6061387 chpB Escherichia coli str. K-12 substr. DH10B toxin ChpB YP_001732989.1 4547077 D 316385 CDS YP_001732990.1 170083670 6060756 complement(4547507..4548037) 1 NC_010473.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4548037 ppa 6060756 ppa Escherichia coli str. K-12 substr. DH10B inorganic pyrophosphatase YP_001732990.1 4547507 R 316385 CDS YP_001732991.1 170083671 6061357 4548347..4549303 1 NC_010473.1 sugar ABC transporter periplasmic-binding protein 4549303 ytfQ 6061357 ytfQ Escherichia coli str. K-12 substr. DH10B sugar ABC transporter periplasmic-binding protein YP_001732991.1 4548347 D 316385 CDS YP_001732992.1 170083672 6061360 4549443..4550945 1 NC_010473.1 sugar ABC transporter ATP-binding protein 4550945 ytfR 6061360 ytfR Escherichia coli str. K-12 substr. DH10B sugar ABC transporter ATP-binding protein YP_001732992.1 4549443 D 316385 CDS YP_001732993.1 170083673 6061785 4553414..4554409 1 NC_010473.1 membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4554409 yjfF 6061785 yjfF Escherichia coli str. K-12 substr. DH10B inner membrane ABC transporter permease YjfF YP_001732993.1 4553414 D 316385 CDS YP_001732994.1 170083674 6061350 complement(4554442..4555440) 1 NC_010473.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4555440 fbp 6061350 fbp Escherichia coli str. K-12 substr. DH10B fructose-1,6-bisphosphatase YP_001732994.1 4554442 R 316385 CDS YP_001732995.1 170083675 6061338 4555616..4556989 1 NC_010473.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4556989 mpl 6061338 mpl Escherichia coli str. K-12 substr. DH10B UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_001732995.1 4555616 D 316385 CDS YP_001732996.1 170083676 6060720 complement(4557145..4557696) 1 NC_010473.1 hypothetical protein 4557696 yjgA 6060720 yjgA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001732996.1 4557145 R 316385 CDS YP_001732997.1 170083677 6061245 4557790..4559142 1 NC_010473.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4559142 pmbA 6061245 pmbA Escherichia coli str. K-12 substr. DH10B peptidase PmbA YP_001732997.1 4557790 D 316385 CDS YP_001732998.1 170083678 6059177 complement(4559731..4560195) 1 NC_010473.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4560195 nrdG 6059177 nrdG Escherichia coli str. K-12 substr. DH10B anaerobic ribonucleotide reductase-activating protein YP_001732998.1 4559731 R 316385 CDS YP_001732999.1 170083679 6061201 complement(4560353..4562491) 1 NC_010473.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4562491 nrdD 6061201 nrdD Escherichia coli str. K-12 substr. DH10B anaerobic ribonucleoside triphosphate reductase YP_001732999.1 4560353 R 316385 CDS YP_001733000.1 170083680 6061110 complement(4562885..4564540) 1 NC_010473.1 trehalose-6-phosphate hydrolase 4564540 treC 6061110 treC Escherichia coli str. K-12 substr. DH10B trehalose-6-phosphate hydrolase YP_001733000.1 4562885 R 316385 CDS YP_001733001.1 170083681 6060993 complement(4564590..4566011) 1 NC_010473.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 4566011 treB 6060993 treB Escherichia coli str. K-12 substr. DH10B PTS system trehalose(maltose)-specific transporter subunit IIBC YP_001733001.1 4564590 R 316385 CDS YP_001733002.1 170083682 6061194 complement(4566130..4567077) 1 NC_010473.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4567077 treR 6061194 treR Escherichia coli str. K-12 substr. DH10B trehalose repressor YP_001733002.1 4566130 R 316385 CDS YP_001733003.1 170083683 6061172 4567456..4570152 1 NC_010473.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4570152 mgtA 6061172 mgtA Escherichia coli str. K-12 substr. DH10B magnesium-transporting ATPase MgtA YP_001733003.1 4567456 D 316385 CDS YP_001733004.1 170083684 6059102 complement(4570358..4570744) 1 NC_010473.1 ketoacid-binding protein 4570744 yjgF 6059102 yjgF Escherichia coli str. K-12 substr. DH10B ketoacid-binding protein YP_001733004.1 4570358 R 316385 CDS YP_001733005.1 170083685 6061923 complement(4570817..4571278) 1 NC_010473.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 4571278 pyrI 6061923 pyrI Escherichia coli str. K-12 substr. DH10B aspartate carbamoyltransferase regulatory subunit YP_001733005.1 4570817 R 316385 CDS YP_001733006.1 170083686 6061951 complement(4571291..4572226) 1 NC_010473.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4572226 pyrB 6061951 pyrB Escherichia coli str. K-12 substr. DH10B aspartate carbamoyltransferase catalytic subunit YP_001733006.1 4571291 R 316385 CDS YP_001733007.1 170083687 6062137 complement(4572230..4572364) 1 NC_010473.1 pyrBI operon leader peptide 4572364 pyrL 6062137 pyrL Escherichia coli str. K-12 substr. DH10B pyrBI operon leader peptide YP_001733007.1 4572230 R 316385 CDS YP_001733008.1 170083688 6062251 complement(4572645..4573040) 1 NC_010473.1 mRNA endoribonuclease 4573040 yjgH 6062251 yjgH Escherichia coli str. K-12 substr. DH10B mRNA endoribonuclease YP_001733008.1 4572645 R 316385 CDS YP_001733009.1 170083689 6062263 complement(4573171..4573884) 1 NC_010473.1 oxidoreductase 4573884 yjgI 6062263 yjgI Escherichia coli str. K-12 substr. DH10B oxidoreductase YP_001733009.1 4573171 R 316385 CDS YP_001733010.1 170083690 6059348 4573955..4574548 1 NC_010473.1 transcriptional regulator 4574548 yjgJ 6059348 yjgJ Escherichia coli str. K-12 substr. DH10B transcriptional regulator YP_001733010.1 4573955 D 316385 CDS YP_001733011.1 170083691 6059877 4574693..4575145 1 NC_010473.1 hypothetical protein 4575145 yjgK 6059877 yjgK Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733011.1 4574693 D 316385 CDS YP_001733012.1 170083692 6060081 4575268..4577082 1 NC_010473.1 hypothetical protein 4577082 yjgL 6060081 yjgL Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733012.1 4575268 D 316385 CDS YP_001733013.1 170083693 6060776 complement(4577138..4578142) 1 NC_010473.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 4578142 argI 6060776 argI Escherichia coli str. K-12 substr. DH10B ornithine carbamoyltransferase subunit I YP_001733013.1 4577138 R 316385 CDS YP_001733014.1 170083694 6058694 4578304..4578720 1 NC_010473.1 hypothetical protein 4578720 rraB 6058694 rraB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733014.1 4578304 D 316385 CDS YP_001733015.1 170083695 6058692 complement(4578865..4579368) 1 NC_010473.1 acetyltransferase 4579368 yjgM 6058692 yjgM Escherichia coli str. K-12 substr. DH10B acetyltransferase YP_001733015.1 4578865 R 316385 CDS YP_001733016.1 170083696 6058744 4579561..4580757 1 NC_010473.1 inner membrane protein 4580757 yjgN 6058744 yjgN Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001733016.1 4579561 D 316385 CDS YP_001733017.1 170083697 6060190 complement(4580813..4583668) 1 NC_010473.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4583668 valS 6060190 valS Escherichia coli str. K-12 substr. DH10B valyl-tRNA synthetase YP_001733017.1 4580813 R 316385 CDS YP_001733018.1 170083698 6060883 complement(4583668..4584111) 1 NC_010473.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4584111 holC 6060883 holC Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit chi YP_001733018.1 4583668 R 316385 CDS YP_001733019.1 170083699 6058826 complement(4584271..4585782) 1 NC_010473.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4585782 pepA 6058826 pepA Escherichia coli str. K-12 substr. DH10B leucyl aminopeptidase YP_001733019.1 4584271 R 316385 CDS YP_001733020.1 170083700 6058898 4586049..4587149 1 NC_010473.1 inner membrane protein 4587149 yjgP 6058898 yjgP Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001733020.1 4586049 D 316385 CDS YP_001733021.1 170083701 6058902 4587149..4588231 1 NC_010473.1 inner membrane protein 4588231 yjgQ 6058902 yjgQ Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001733021.1 4587149 D 316385 CDS YP_001733022.1 170083702 6058901 complement(4588392..4589894) 1 NC_010473.1 ATPase 4589894 yjgR 6058901 yjgR Escherichia coli str. K-12 substr. DH10B ATPase YP_001733022.1 4588392 R 316385 CDS YP_001733023.1 170083703 6058933 complement(4589972..4590970) 1 NC_010473.1 DNA-binding transcriptional repressor, 5-gluconate-binding 4590970 idnR 6058933 idnR Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional repressor, 5-gluconate-binding YP_001733023.1 4589972 R 316385 CDS YP_001733024.1 170083704 6058935 complement(4591037..4592356) 1 NC_010473.1 L-idonate and D-gluconate transporter 4592356 idnT 6058935 idnT Escherichia coli str. K-12 substr. DH10B L-idonate and D-gluconate transporter YP_001733024.1 4591037 R 316385 CDS YP_001733025.1 170083705 6058976 complement(4592418..4593182) 1 NC_010473.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 4593182 idnO 6058976 idnO Escherichia coli str. K-12 substr. DH10B gluconate 5-dehydrogenase YP_001733025.1 4592418 R 316385 CDS YP_001733026.1 170083706 6058999 complement(4593206..4594237) 1 NC_010473.1 NAD-binding; L-idonate 5-dehydrogenase 4594237 idnD 6058999 idnD Escherichia coli str. K-12 substr. DH10B L-idonate 5-dehydrogenase YP_001733026.1 4593206 R 316385 CDS YP_001733027.1 170083707 6060389 4594454..4595017 1 NC_010473.1 D-gluconate kinase 4595017 idnK 6060389 idnK Escherichia coli str. K-12 substr. DH10B D-gluconate kinase YP_001733027.1 4594454 D 316385 CDS YP_001733028.1 170083708 6058993 complement(4595021..4596040) 1 NC_010473.1 Zn-dependent/NAD(P)-binding alcohol dehydrogenase 4596040 yjgB 6058993 yjgB Escherichia coli str. K-12 substr. DH10B Zn-dependent/NAD(P)-binding alcohol dehydrogenase YP_001733028.1 4595021 R 316385 CDS YP_001733029.1 170083709 6059987 4596581..4597771 1 NC_010473.1 KpLE2 phage-like element; integrase 4597771 intB 6059987 intB Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; integrase YP_001733029.1 4596581 D 316385 CDS YP_001733030.1 170083710 6059063 4598058..4598468 1 NC_010473.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 4598468 insC-6 6059063 insC-6 Escherichia coli str. K-12 substr. DH10B insertion sequence 2 OrfA protein YP_001733030.1 4598058 D 316385 CDS YP_001733031.1 170083711 6058996 4598426..4599331 1 NC_010473.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 4599331 insD-6 6058996 insD-6 Escherichia coli str. K-12 substr. DH10B insertion element IS2 transposase InsD YP_001733031.1 4598426 D 316385 CDS YP_001733032.1 170083712 6059067 4599430..4599765 1 NC_010473.1 KpLE2 phage-like element; protein 4599765 yjgW 6059067 yjgW Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; protein YP_001733032.1 4599430 D 316385 CDS YP_001733033.1 170083713 6059085 4601091..4601420 1 NC_010473.1 KpLE2 phage-like element; protein 4601420 yjgZ 6059085 yjgZ Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; protein YP_001733033.1 4601091 D 316385 CDS YP_001733034.1 170083714 6059096 complement(4601934..4603262) 1 NC_010473.1 KpLE2 phage-like element; IS4 transposase 4603262 insG 6059096 insG Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; IS4 transposase YP_001733034.1 4601934 R 316385 CDS YP_001733035.1 170083715 6059107 4603889..4605106 1 NC_010473.1 putative sialic acid transporter 4605106 yjhB 6059107 yjhB Escherichia coli str. K-12 substr. DH10B putative sialic acid transporter YP_001733035.1 4603889 D 316385 CDS YP_001733036.1 170083716 6059103 4605118..4606236 1 NC_010473.1 KpLE2 phage-like element; oxidoreductase 4606236 yjhC 6059103 yjhC Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; oxidoreductase YP_001733036.1 4605118 D 316385 CDS YP_001733037.1 170083717 6059539 4607028..4607294 1 NC_010473.1 KpLE2 phage-like element; partial regulator of insertion element IS911B 4607294 insN-2 6059539 insN-2 Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; partial regulator of insertion element IS911B YP_001733037.1 4607028 D 316385 CDS YP_001733038.1 170083718 6059185 complement(4607297..4608448) 1 NC_010473.1 KpLE2 phage-like element; IS30 transposase 4608448 insI-3 6059185 insI-3 Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; IS30 transposase YP_001733038.1 4607297 R 316385 CDS YP_001733039.1 170083719 6059133 4608789..4609385 1 NC_010473.1 KpLE2 phage-like element; partial transposase of insertion element IS911B 4609385 insO-2 6059133 insO-2 Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; partial transposase of insertion element IS911B YP_001733039.1 4608789 D 316385 CDS YP_001733040.1 170083720 6061720 4609551..4609964 1 NC_010473.1 KpLE2 phage-like element; protein 4609964 yjhV 6061720 yjhV Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; protein YP_001733040.1 4609551 D 316385 CDS YP_001733041.1 170083721 6059240 complement(4610521..4611288) 1 NC_010473.1 Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit 4611288 fecE 6059240 fecE Escherichia coli str. K-12 substr. DH10B iron-dicitrate transporter ATP-binding subunit YP_001733041.1 4610521 R 316385 CDS YP_001733042.1 170083722 6059264 complement(4611289..4612245) 1 NC_010473.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD 4612245 fecD 6059264 fecD Escherichia coli str. K-12 substr. DH10B iron-dicitrate transporter subunit FecD YP_001733042.1 4611289 R 316385 CDS YP_001733043.1 170083723 6059279 complement(4612242..4613240) 1 NC_010473.1 part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease subunit 4613240 fecC 6059279 fecC Escherichia coli str. K-12 substr. DH10B iron-dicitrate transporter permease subunit YP_001733043.1 4612242 R 316385 CDS YP_001733044.1 170083724 6061791 complement(4613237..4614139) 1 NC_010473.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit 4614139 fecB 6061791 fecB Escherichia coli str. K-12 substr. DH10B iron-dicitrate transporter substrate-binding subunit YP_001733044.1 4613237 R 316385 CDS YP_001733045.1 170083725 6059339 complement(4614184..4616508) 1 NC_010473.1 KpLE2 phage-like element; ferric citrate outer membrane transporter 4616508 fecA 6059339 fecA Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; ferric citrate outer membrane transporter YP_001733045.1 4614184 R 316385 CDS YP_001733046.1 170083726 6059305 complement(4616595..4617548) 1 NC_010473.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR 4617548 fecR 6059305 fecR Escherichia coli str. K-12 substr. DH10B fec operon regulator FecR YP_001733046.1 4616595 R 316385 CDS YP_001733047.1 170083727 6061900 complement(4617545..4618066) 1 NC_010473.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI 4618066 fecI 6061900 fecI Escherichia coli str. K-12 substr. DH10B RNA polymerase sigma factor FecI YP_001733047.1 4617545 R 316385 CDS YP_001733048.1 170083728 6059500 4618358..4618633 1 NC_010473.1 KpLE2 phage-like element; IS1 repressor protein InsA 4618633 insA-7 6059500 insA-7 Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; IS1 repressor protein InsA YP_001733048.1 4618358 D 316385 CDS YP_001733049.1 170083729 6058186 complement(4619169..4620155) 1 NC_010473.1 KpLE2 phage-like element; DNA-binding transcriptional regulator 4620155 yjhU 6058186 yjhU Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; DNA-binding transcriptional regulator YP_001733049.1 4619169 R 316385 CDS YP_001733050.1 170083730 6058765 complement(4620502..4621851) 1 NC_010473.1 KpLE2 phage-like element; transporter 4621851 yjhF 6058765 yjhF Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; transporter YP_001733050.1 4620502 R 316385 CDS YP_001733051.1 170083731 6058776 complement(4621958..4623925) 1 NC_010473.1 hypothetical protein 4623925 yjhG 6058776 yjhG Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733051.1 4621958 R 316385 CDS YP_001733052.1 170083732 6058800 complement(4623936..4624841) 1 NC_010473.1 KpLE2 phage-like element; lyase/synthase 4624841 yjhH 6058800 yjhH Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; lyase/synthase YP_001733052.1 4623936 R 316385 CDS YP_001733053.1 170083733 6058806 complement(4624846..4625634) 1 NC_010473.1 KpLE2 phage-like element; DNA-binding transcriptional regulator 4625634 yjhI 6058806 yjhI Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; DNA-binding transcriptional regulator YP_001733053.1 4624846 R 316385 CDS YP_001733054.1 170083734 6059442 complement(4625937..4626719) 1 NC_010473.1 KpLE2 phage-like element; DNA-binding transcriptional regulator 4626719 sgcR 6059442 sgcR Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; DNA-binding transcriptional regulator YP_001733054.1 4625937 R 316385 CDS YP_001733055.1 170083735 6059413 complement(4626736..4627368) 1 NC_010473.1 epimerase 4627368 sgcE 6059413 sgcE Escherichia coli str. K-12 substr. DH10B epimerase YP_001733055.1 4626736 R 316385 CDS YP_001733056.1 170083736 6059407 complement(4627380..4627811) 1 NC_010473.1 KpLE2 phage-like element; phosphotransferase enzyme IIA component 4627811 sgcA 6059407 sgcA Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; phosphotransferase enzyme IIA component YP_001733056.1 4627380 R 316385 CDS YP_001733057.1 170083737 6058858 complement(4627942..4628748) 1 NC_010473.1 KpLE2 phage-like element; nucleoside triphosphatase 4628748 sgcQ 6058858 sgcQ Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; nucleoside triphosphatase YP_001733057.1 4627942 R 316385 CDS YP_001733058.1 170083738 6059456 complement(4628761..4630074) 1 NC_010473.1 KpLE2 phage-like element; phosphotransferase enzyme IIC component 4630074 sgcC 6059456 sgcC Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; phosphotransferase enzyme IIC component YP_001733058.1 4628761 R 316385 CDS YP_001733059.1 170083739 6059395 complement(4630086..4630364) 1 NC_010473.1 enzyme IIB component of PTS 4630364 sgcB 6059395 sgcB Escherichia coli str. K-12 substr. DH10B enzyme IIB component of PTS YP_001733059.1 4630086 R 316385 CDS YP_001733060.1 170083740 6059564 complement(4630361..4631482) 1 NC_010473.1 KpLE2 phage-like element 4631482 sgcX 6059564 sgcX Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element YP_001733060.1 4630361 R 316385 CDS YP_001733061.1 170083741 6059527 complement(4632268..4633014) 1 NC_010473.1 KpLE2 phage-like element; methyltransferase 4633014 yjhP 6059527 yjhP Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; methyltransferase YP_001733061.1 4632268 R 316385 CDS YP_001733062.1 170083742 6059587 complement(4633070..4633615) 1 NC_010473.1 KpLE2 phage-like element; acetyltransferase 4633615 yjhQ 6059587 yjhQ Escherichia coli str. K-12 substr. DH10B KpLE2 phage-like element; acetyltransferase YP_001733062.1 4633070 R 316385 CDS YP_001733063.1 170083743 6059663 complement(4633627..4633884) 1 NC_010473.1 hypothetical protein 4633884 yjhX 6059663 yjhX Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733063.1 4633627 R 316385 CDS YP_001733064.1 170083744 6058895 complement(4636445..4637425) 1 NC_010473.1 hypothetical protein 4637425 yjhS 6058895 yjhS Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733064.1 4636445 R 316385 CDS YP_001733065.1 170083745 6058492 complement(4637490..4638596) 1 NC_010473.1 N-acetylneuraminic acid mutarotase 4638596 yjhT 6058492 yjhT Escherichia coli str. K-12 substr. DH10B N-acetylneuraminic acid mutarotase YP_001733065.1 4637490 R 316385 CDS YP_001733066.1 170083746 6059055 complement(4638616..4639332) 1 NC_010473.1 N-acetylnuraminic acid outer membrane channel protein 4639332 yjhA 6059055 yjhA Escherichia coli str. K-12 substr. DH10B N-acetylnuraminic acid outer membrane channel protein YP_001733066.1 4638616 R 316385 CDS YP_001733067.1 170083747 6058931 complement(4644180..4644674) 1 NC_010473.1 hypothetical protein 4644674 yjjA 6058931 yjjA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733067.1 4644180 R 316385 CDS YP_001733068.1 170083748 6059802 complement(4644723..4645460) 1 NC_010473.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4645460 dnaC 6059802 dnaC Escherichia coli str. K-12 substr. DH10B DNA replication protein DnaC YP_001733068.1 4644723 R 316385 CDS YP_001733069.1 170083749 6059778 complement(4645463..4646002) 1 NC_010473.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4646002 dnaT 6059778 dnaT Escherichia coli str. K-12 substr. DH10B primosomal protein DnaI YP_001733069.1 4645463 R 316385 CDS YP_001733070.2 228937033 6059878 complement(4646109..4646582) 1 NC_010473.1 hypothetical protein 4646582 yjjB 6059878 yjjB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733070.2 4646109 R 316385 CDS YP_001733071.1 170083751 6060000 complement(4646573..4647343) 1 NC_010473.1 inner membrane protein 4647343 yjjP 6060000 yjjP Escherichia coli str. K-12 substr. DH10B inner membrane protein YP_001733071.1 4646573 R 316385 CDS YP_001733072.1 170083752 6060022 4647962..4648687 1 NC_010473.1 DNA-binding transcriptional regulator 4648687 yjjQ 6060022 yjjQ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional regulator YP_001733072.1 4647962 D 316385 CDS YP_001733073.1 170083753 6059792 4648699..4649322 1 NC_010473.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4649322 bglJ 6059792 bglJ Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator BglJ YP_001733073.1 4648699 D 316385 CDS YP_001733074.1 170083754 6060481 complement(4649360..4650148) 1 NC_010473.1 ferric hydroximate transport ferric iron reductase 4650148 fhuF 6060481 fhuF Escherichia coli str. K-12 substr. DH10B ferric hydroximate transport ferric iron reductase YP_001733074.1 4649360 R 316385 CDS YP_001733075.1 170083755 6060115 4650289..4650525 1 NC_010473.1 hypothetical protein 4650525 yjjZ 6060115 yjjZ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733075.1 4650289 D 316385 CDS YP_001733076.1 170083756 6059966 complement(4651154..4652185) 1 NC_010473.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4652185 rsmC 6059966 rsmC Escherichia coli str. K-12 substr. DH10B 16S ribosomal RNA m2G1207 methyltransferase YP_001733076.1 4651154 R 316385 CDS YP_001733077.1 170083757 6060169 4652288..4652701 1 NC_010473.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4652701 holD 6060169 holD Escherichia coli str. K-12 substr. DH10B DNA polymerase III subunit psi YP_001733077.1 4652288 D 316385 CDS YP_001733078.1 170083758 6060177 4652670..4653116 1 NC_010473.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4653116 rimI 6060177 rimI Escherichia coli str. K-12 substr. DH10B ribosomal-protein-alanine N-acetyltransferase YP_001733078.1 4652670 D 316385 CDS YP_001733079.1 170083759 6059754 4653131..4653808 1 NC_010473.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4653808 yjjG 6059754 yjjG Escherichia coli str. K-12 substr. DH10B nucleotidase YP_001733079.1 4653131 D 316385 CDS YP_001733080.1 170083760 6060201 4653899..4655488 1 NC_010473.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4655488 prfC 6060201 prfC Escherichia coli str. K-12 substr. DH10B peptide chain release factor 3 YP_001733080.1 4653899 D 316385 CDS YP_001733081.1 170083761 6060240 4655881..4656486 1 NC_010473.1 hypothetical protein 4656486 osmY 6060240 osmY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733081.1 4655881 D 316385 CDS YP_001733082.1 170083762 6060244 4656595..4656774 1 NC_010473.1 hypothetical protein 4656774 ytjA 6060244 ytjA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733082.1 4656595 D 316385 CDS YP_001733083.1 170083763 6060263 4656896..4657969 1 NC_010473.1 esterase 4657969 yjjU 6060263 yjjU Escherichia coli str. K-12 substr. DH10B esterase YP_001733083.1 4656896 D 316385 CDS YP_001733084.1 170083764 6059351 4657966..4658745 1 NC_010473.1 putative deoxyribonuclease YjjV 4658745 yjjV 6059351 yjjV Escherichia coli str. K-12 substr. DH10B putative deoxyribonuclease YjjV YP_001733084.1 4657966 D 316385 CDS YP_001733085.1 170083765 6060262 complement(4659165..4660028) 1 NC_010473.1 pyruvate formate lyase activating enzyme 4660028 yjjW 6060262 yjjW Escherichia coli str. K-12 substr. DH10B pyruvate formate lyase activating enzyme YP_001733085.1 4659165 R 316385 CDS YP_001733086.1 170083766 6060286 complement(4660000..4661550) 1 NC_010473.1 hypothetical protein 4661550 yjjI 6060286 yjjI Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733086.1 4660000 R 316385 CDS YP_001733087.1 170083767 6060343 4661808..4662587 1 NC_010473.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4662587 deoC 6060343 deoC Escherichia coli str. K-12 substr. DH10B deoxyribose-phosphate aldolase YP_001733087.1 4661808 D 316385 CDS YP_001733088.1 170083768 6060363 4662714..4664036 1 NC_010473.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4664036 deoA 6060363 deoA Escherichia coli str. K-12 substr. DH10B thymidine phosphorylase YP_001733088.1 4662714 D 316385 CDS YP_001733089.1 170083769 6060377 4664088..4665311 1 NC_010473.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4665311 deoB 6060377 deoB Escherichia coli str. K-12 substr. DH10B phosphopentomutase YP_001733089.1 4664088 D 316385 CDS YP_001733090.1 170083770 6058701 4665368..4666087 1 NC_010473.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4666087 deoD 6058701 deoD Escherichia coli str. K-12 substr. DH10B purine nucleoside phosphorylase YP_001733090.1 4665368 D 316385 CDS YP_001733091.1 170083771 6058313 4666254..4667585 1 NC_010473.1 hypothetical protein 4667585 yjjJ 6058313 yjjJ Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733091.1 4666254 D 316385 CDS YP_001733092.1 170083772 6060411 complement(4667586..4668602) 1 NC_010473.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 4668602 lplA 6060411 lplA Escherichia coli str. K-12 substr. DH10B lipoate-protein ligase A YP_001733092.1 4667586 R 316385 CDS YP_001733093.1 170083773 6060419 complement(4668630..4669274) 1 NC_010473.1 hypothetical protein 4669274 ytjB 6060419 ytjB Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733093.1 4668630 R 316385 CDS YP_001733094.1 170083774 6058202 4669380..4670348 1 NC_010473.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4670348 serB 6058202 serB Escherichia coli str. K-12 substr. DH10B phosphoserine phosphatase YP_001733094.1 4669380 D 316385 CDS YP_001733095.1 170083775 6060422 4670397..4671779 1 NC_010473.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4671779 radA 6060422 radA Escherichia coli str. K-12 substr. DH10B DNA repair protein RadA YP_001733095.1 4670397 D 316385 CDS YP_001733096.1 170083776 6060431 4671800..4673032 1 NC_010473.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4673032 nadR 6060431 nadR Escherichia coli str. K-12 substr. DH10B nicotinamide-nucleotide adenylyltransferase YP_001733096.1 4671800 D 316385 CDS YP_001733097.1 170083777 6060436 complement(4673340..4675007) 1 NC_010473.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 4675007 yjjK 6060436 yjjK Escherichia coli str. K-12 substr. DH10B putative ABC transporter ATP-binding protein YP_001733097.1 4673340 R 316385 CDS YP_001733098.1 170083778 6059751 4675218..4677155 1 NC_010473.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4677155 slt 6059751 slt Escherichia coli str. K-12 substr. DH10B lytic murein transglycosylase YP_001733098.1 4675218 D 316385 CDS YP_001733099.1 170083779 6062195 4677245..4677571 1 NC_010473.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4677571 trpR 6062195 trpR Escherichia coli str. K-12 substr. DH10B Trp operon repressor YP_001733099.1 4677245 D 316385 CDS YP_001733100.1 170083780 6059301 complement(4677718..4678230) 1 NC_010473.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 4678230 yjjX 6059301 yjjX Escherichia coli str. K-12 substr. DH10B NTPase YP_001733100.1 4677718 R 316385 CDS YP_001733101.1 170083781 6058703 4678282..4678929 1 NC_010473.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4678929 ytjC 6058703 ytjC Escherichia coli str. K-12 substr. DH10B phosphoglycerate mutase YP_001733101.1 4678282 D 316385 CDS YP_001733102.1 170083782 6061772 complement(4678926..4679795) 1 NC_010473.1 DNA-binding transcriptional activator 4679795 rob 6061772 rob Escherichia coli str. K-12 substr. DH10B DNA-binding transcriptional activator YP_001733102.1 4678926 R 316385 CDS YP_001733103.1 170083783 6061351 4680006..4680479 1 NC_010473.1 hypothetical protein 4680479 creA 6061351 creA Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733103.1 4680006 D 316385 CDS YP_001733104.1 170083784 6059119 4680492..4681181 1 NC_010473.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4681181 creB 6059119 creB Escherichia coli str. K-12 substr. DH10B DNA-binding response regulator CreB YP_001733104.1 4680492 D 316385 CDS YP_001733105.1 170083785 6062403 4681181..4682605 1 NC_010473.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4682605 creC 6062403 creC Escherichia coli str. K-12 substr. DH10B sensory histidine kinase CreC YP_001733105.1 4681181 D 316385 CDS YP_001733106.1 170083786 6062034 4682663..4684015 1 NC_010473.1 hypothetical protein 4684015 creD 6062034 creD Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733106.1 4682663 D 316385 CDS YP_001733107.1 170083787 6060398 complement(4684075..4684791) 1 NC_010473.1 two-component response regulator 4684791 arcA 6060398 arcA Escherichia coli str. K-12 substr. DH10B two-component response regulator YP_001733107.1 4684075 R 316385 CDS YP_001733108.1 170083788 6060432 4684887..4685027 1 NC_010473.1 hypothetical protein 4685027 yjjY 6060432 yjjY Escherichia coli str. K-12 substr. DH10B hypothetical protein YP_001733108.1 4684887 D 316385 CDS YP_001733109.1 170083789 6060413 4685427..4686113 1 NC_010473.1 member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase 4686113 yjtD 6060413 yjtD Escherichia coli str. K-12 substr. DH10B putative RNA methyltransferase YP_001733109.1 4685427 D 316385 CDS