-- dump date 20140619_070331 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 269484000001 SEQ_END SEQ_END NC_007354.1 1315030 1315030 DR NC_007354.1; contig end 1315030..1315030 Ehrlichia canis str. Jake YP_302650.1 CDS Ecaj_0001 NC_007354.1 475 1647 D 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 475..1647 Ehrlichia canis str. Jake 3617744 YP_302651.1 CDS Ecaj_0002 NC_007354.1 1644 2204 R hypothetical protein complement(1644..2204) Ehrlichia canis str. Jake 3617745 YP_302652.1 CDS glyQ NC_007354.1 2588 3430 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 2588..3430 Ehrlichia canis str. Jake 3618218 YP_302653.1 CDS Ecaj_0004 NC_007354.1 3446 5551 D glycyl-tRNA synthetase subunit beta 3446..5551 Ehrlichia canis str. Jake 3618219 YP_302654.1 CDS Ecaj_0005 NC_007354.1 5613 6761 D DnaJ central domain (CXXCXGXG):Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal; chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 5613..6761 Ehrlichia canis str. Jake 3618220 YP_302655.1 CDS Ecaj_0006 NC_007354.1 7496 8323 R nicotinate-nucleotide pyrophosphorylase complement(7496..8323) Ehrlichia canis str. Jake 3618221 YP_302656.1 CDS Ecaj_0007 NC_007354.1 8415 8990 D membrane protein 8415..8990 Ehrlichia canis str. Jake 3618222 YP_302657.1 CDS Ecaj_0008 NC_007354.1 8996 9466 R Holliday junction endonuclease RuvC complement(8996..9466) Ehrlichia canis str. Jake 3618223 YP_302658.1 CDS Ecaj_0009 NC_007354.1 9468 10292 R cytochrome c oxidase subunit III complement(9468..10292) Ehrlichia canis str. Jake 3618224 YP_302659.1 CDS Ecaj_0010 NC_007354.1 10390 11394 R uroporphyrinogen decarboxylase HemE complement(10390..11394) Ehrlichia canis str. Jake 3618225 YP_302660.1 CDS Ecaj_0011 NC_007354.1 11820 12707 D CBS/transport-associated domain-containing protein 11820..12707 Ehrlichia canis str. Jake 3618226 YP_302661.1 CDS Ecaj_0012 NC_007354.1 12690 13223 R prohead peptidase complement(12690..13223) Ehrlichia canis str. Jake 3618227 YP_302662.1 CDS Ecaj_0013 NC_007354.1 13333 14514 R HK97 family phage portal protein complement(13333..14514) Ehrlichia canis str. Jake 3618228 YP_302663.1 CDS Ecaj_0014 NC_007354.1 14770 15531 D putative methylase involved in ubiquinone/menaquinone biosynthesis 14770..15531 Ehrlichia canis str. Jake 3618229 YP_302664.1 CDS Ecaj_0015 NC_007354.1 15553 16494 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 15553..16494 Ehrlichia canis str. Jake 3618230 YP_302665.1 CDS Ecaj_0016 NC_007354.1 16694 17071 R 4Fe-4S ferredoxin complement(16694..17071) Ehrlichia canis str. Jake 3618231 YP_302666.1 CDS Ecaj_0017 NC_007354.1 17335 19401 D gp140 17335..19401 Ehrlichia canis str. Jake 3618232 YP_302667.1 CDS Ecaj_0018 NC_007354.1 19831 22002 R type IV secretion system protein VirB8 complement(19831..22002) Ehrlichia canis str. Jake 3618233 YP_302668.1 CDS Ecaj_0019 NC_007354.1 22041 23039 R type IV secretion system ATPase VirB11 complement(22041..23039) Ehrlichia canis str. Jake 3618234 YP_302669.1 CDS Ecaj_0020 NC_007354.1 23056 24393 R conjugation TrbI-like protein complement(23056..24393) Ehrlichia canis str. Jake 3618235 YP_302670.1 CDS Ecaj_0021 NC_007354.1 24415 25239 R conjugal transfer protein TrbG/VirB9/CagX complement(24415..25239) Ehrlichia canis str. Jake 3618236 YP_302671.1 CDS Ecaj_0022 NC_007354.1 25226 25930 R virulence protein complement(25226..25930) Ehrlichia canis str. Jake 3617558 YP_302672.1 CDS Ecaj_0023 NC_007354.1 26023 27165 R GTP cyclohydrolase II complement(26023..27165) Ehrlichia canis str. Jake 3617559 YP_302673.1 CDS Ecaj_0024 NC_007354.1 27624 28694 R hypothetical protein complement(27624..28694) Ehrlichia canis str. Jake 3618493 YP_302674.1 CDS Ecaj_0025 NC_007354.1 28769 29353 R hypothetical protein complement(28769..29353) Ehrlichia canis str. Jake 3618508 YP_302675.1 CDS Ecaj_0026 NC_007354.1 29334 30137 R diaminopimelate epimerase complement(29334..30137) Ehrlichia canis str. Jake 3618494 YP_302676.1 CDS Ecaj_0027 NC_007354.1 30388 30819 R hypothetical protein complement(30388..30819) Ehrlichia canis str. Jake 3618205 YP_302677.1 CDS pgk NC_007354.1 31580 32764 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 31580..32764 Ehrlichia canis str. Jake 3618206 YP_302678.1 CDS Ecaj_0029 NC_007354.1 34033 35199 R exodeoxyribonuclease VII large subunit complement(34033..35199) Ehrlichia canis str. Jake 3618207 YP_302679.1 CDS Ecaj_0030 NC_007354.1 35196 35861 R hypothetical protein complement(35196..35861) Ehrlichia canis str. Jake 3618208 YP_302680.2 CDS dapD NC_007354.1 36072 36911 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 36072..36911 Ehrlichia canis str. Jake 3618209 YP_302681.1 CDS trmE NC_007354.1 37192 38517 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 37192..38517 Ehrlichia canis str. Jake 3618210 YP_302682.1 CDS Ecaj_0033 NC_007354.1 39861 40394 R decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase complement(39861..40394) Ehrlichia canis str. Jake 3618211 YP_302683.1 CDS Ecaj_0034 NC_007354.1 40504 42540 D DEAD/DEAH box helicase 40504..42540 Ehrlichia canis str. Jake 3618212 YP_302684.1 CDS Ecaj_0035 NC_007354.1 43875 44837 D NADH-ubiquinone oxidoreductase, putativ 43875..44837 Ehrlichia canis str. Jake 3618213 YP_302685.1 CDS Ecaj_0036 NC_007354.1 44951 45409 R dnaK suppressor protein complement(44951..45409) Ehrlichia canis str. Jake 3618214 YP_302686.1 CDS Ecaj_0037 NC_007354.1 45523 46185 D heme exporter protein CcmB 45523..46185 Ehrlichia canis str. Jake 3618215 YP_302687.1 CDS Ecaj_0038 NC_007354.1 47344 47586 D hypothetical protein 47344..47586 Ehrlichia canis str. Jake 3618216 YP_302688.1 CDS Ecaj_0039 NC_007354.1 47795 48733 D cation efflux protein 47795..48733 Ehrlichia canis str. Jake 3618127 YP_302689.1 CDS Ecaj_0040 NC_007354.1 49085 49714 D putative ABC-type transport system involved in resistance to organic solvents auxiliary component 49085..49714 Ehrlichia canis str. Jake 3618128 YP_302690.1 CDS rpsT NC_007354.1 50131 50418 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(50131..50418) Ehrlichia canis str. Jake 3618129 YP_302691.1 CDS Ecaj_0042 NC_007354.1 50579 51301 R phospholipid/glycerol acyltransferase complement(50579..51301) Ehrlichia canis str. Jake 3618130 YP_302692.1 CDS Ecaj_0043 NC_007354.1 52387 52944 D peptide deformylase 52387..52944 Ehrlichia canis str. Jake 3618131 YP_302693.1 CDS Ecaj_0044 NC_007354.1 52961 53746 D DNA polymerase-like protein 52961..53746 Ehrlichia canis str. Jake 3618132 YP_302694.1 CDS recF NC_007354.1 54279 55397 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(54279..55397) Ehrlichia canis str. Jake 3618133 YP_302695.1 CDS Ecaj_0046 NC_007354.1 56364 57275 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase complement(56364..57275) Ehrlichia canis str. Jake 3618134 YP_302696.1 CDS Ecaj_0047 NC_007354.1 57608 58009 R hypothetical protein complement(57608..58009) Ehrlichia canis str. Jake 3618135 YP_302697.1 CDS Ecaj_0048 NC_007354.1 58330 60915 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 58330..60915 Ehrlichia canis str. Jake 3618136 YP_302698.1 CDS Ecaj_0049 NC_007354.1 61565 62233 D ribulose-5-phosphate 3-epimerase 61565..62233 Ehrlichia canis str. Jake 3618137 YP_302699.1 CDS Ecaj_0050 NC_007354.1 62869 63666 D hypothetical protein 62869..63666 Ehrlichia canis str. Jake 3618138 YP_302700.1 CDS Ecaj_0051 NC_007354.1 63678 64394 D ABC transporter 63678..64394 Ehrlichia canis str. Jake 3618139 YP_302701.1 CDS Ecaj_0052 NC_007354.1 64518 66359 D ankyrin 64518..66359 Ehrlichia canis str. Jake 3618504 YP_302702.1 CDS Ecaj_0053 NC_007354.1 66806 67783 R trans-hexaprenyltrans transferase complement(66806..67783) Ehrlichia canis str. Jake 3618357 YP_302703.1 CDS Ecaj_0054 NC_007354.1 67973 69445 R L-glutamine synthetase complement(67973..69445) Ehrlichia canis str. Jake 3618358 YP_302704.1 CDS Ecaj_0055 NC_007354.1 69692 70948 D tyrosyl-tRNA synthetase 69692..70948 Ehrlichia canis str. Jake 3618475 YP_302705.1 CDS Ecaj_0056 NC_007354.1 70974 72170 D catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 70974..72170 Ehrlichia canis str. Jake 3618476 YP_302706.1 CDS Ecaj_0057 NC_007354.1 72177 72545 R hypothetical protein complement(72177..72545) Ehrlichia canis str. Jake 3618477 YP_302707.1 CDS secF NC_007354.1 73737 74618 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 73737..74618 Ehrlichia canis str. Jake 3618478 YP_302708.1 CDS Ecaj_0059 NC_007354.1 75792 76697 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(75792..76697) Ehrlichia canis str. Jake 3617831 YP_302709.1 CDS Ecaj_0060 NC_007354.1 77108 88252 D hypothetical protein 77108..88252 Ehrlichia canis str. Jake 3617832 YP_302710.1 CDS Ecaj_0061 NC_007354.1 88390 89601 D branched-chain alpha-keto acid dehydrogenase subunit E2 88390..89601 Ehrlichia canis str. Jake 3617833 YP_302711.1 CDS Ecaj_0062 NC_007354.1 90120 92993 D hypothetical protein 90120..92993 Ehrlichia canis str. Jake 3618500 YP_302712.1 CDS Ecaj_0063 NC_007354.1 93462 95579 D hypothetical protein 93462..95579 Ehrlichia canis str. Jake 3618501 YP_302713.1 CDS Ecaj_0064 NC_007354.1 95573 96256 D hypothetical protein 95573..96256 Ehrlichia canis str. Jake 3618502 YP_302714.1 CDS Ecaj_0065 NC_007354.1 96886 98673 D hypothetical protein 96886..98673 Ehrlichia canis str. Jake 3618503 YP_302715.1 CDS Ecaj_0066 NC_007354.1 99063 101732 D hypothetical protein 99063..101732 Ehrlichia canis str. Jake 3618100 YP_302716.1 CDS Ecaj_0067 NC_007354.1 102107 104194 D hypothetical protein 102107..104194 Ehrlichia canis str. Jake 3618101 YP_302717.1 CDS Ecaj_0068 NC_007354.1 104869 106719 D hypothetical protein 104869..106719 Ehrlichia canis str. Jake 3618102 YP_302718.1 CDS Ecaj_0069 NC_007354.1 107083 109554 D hypothetical protein 107083..109554 Ehrlichia canis str. Jake 3618103 YP_302719.1 CDS Ecaj_0070 NC_007354.1 109908 110144 D hypothetical protein 109908..110144 Ehrlichia canis str. Jake 3618104 YP_302720.1 CDS Ecaj_0071 NC_007354.1 110411 112336 D hypothetical protein 110411..112336 Ehrlichia canis str. Jake 3618105 YP_302721.1 CDS Ecaj_0072 NC_007354.1 112504 115254 D hypothetical protein 112504..115254 Ehrlichia canis str. Jake 3618106 YP_302722.1 CDS Ecaj_0073 NC_007354.1 115413 115691 R hypothetical protein complement(115413..115691) Ehrlichia canis str. Jake 3618398 YP_302723.1 CDS guaA NC_007354.1 116089 117669 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 116089..117669 Ehrlichia canis str. Jake 3618399 YP_302724.1 CDS Ecaj_0075 NC_007354.1 118602 119852 D citrate synthase 118602..119852 Ehrlichia canis str. Jake 3618400 YP_302725.1 CDS Ecaj_0076 NC_007354.1 120137 121363 D glutamate--cysteine ligase 120137..121363 Ehrlichia canis str. Jake 3618401 YP_302726.1 CDS Ecaj_0077 NC_007354.1 122319 123323 R DNA polymerase III subunit delta complement(122319..123323) Ehrlichia canis str. Jake 3618402 YP_302727.1 CDS Ecaj_0078 NC_007354.1 123620 124852 D hypothetical protein 123620..124852 Ehrlichia canis str. Jake 3618403 YP_302728.1 CDS Ecaj_0079 NC_007354.1 124865 125653 D hypothetical protein 124865..125653 Ehrlichia canis str. Jake 3618404 YP_302729.1 CDS Ecaj_0080 NC_007354.1 125650 126891 D hypothetical protein 125650..126891 Ehrlichia canis str. Jake 3618405 YP_302730.1 CDS Ecaj_0081 NC_007354.1 126897 127151 D hypothetical protein 126897..127151 Ehrlichia canis str. Jake 3618406 YP_302731.1 CDS Ecaj_0082 NC_007354.1 127933 128484 D H+-transporting two-sector ATPase subunit delta 127933..128484 Ehrlichia canis str. Jake 3618407 YP_302732.1 CDS Ecaj_0083 NC_007354.1 128497 130026 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 128497..130026 Ehrlichia canis str. Jake 3618408 YP_302733.1 CDS Ecaj_0084 NC_007354.1 130038 130550 D transcription elongation factor GreA 130038..130550 Ehrlichia canis str. Jake 3618409 YP_302734.1 CDS Ecaj_0085 NC_007354.1 130568 131203 D 3,4-dihydroxy-2-butanone 4-phosphate synthase 130568..131203 Ehrlichia canis str. Jake 3618410 YP_302735.1 CDS smpB NC_007354.1 131225 131671 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 131225..131671 Ehrlichia canis str. Jake 3618411 YP_302736.1 CDS Ecaj_0087 NC_007354.1 133501 135435 R cytochrome c assembly protein complement(133501..135435) Ehrlichia canis str. Jake 3618412 YP_302737.1 CDS valS NC_007354.1 136407 138815 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 136407..138815 Ehrlichia canis str. Jake 3618413 YP_302738.1 CDS Ecaj_0089 NC_007354.1 139464 140300 D glycine cleavage T protein(aminomethyl transferase) 139464..140300 Ehrlichia canis str. Jake 3618414 YP_302739.1 CDS Ecaj_0090 NC_007354.1 141348 142736 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(141348..142736) Ehrlichia canis str. Jake 3618415 YP_302740.1 CDS Ecaj_0091 NC_007354.1 143984 144565 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(143984..144565) Ehrlichia canis str. Jake 3618416 YP_302741.1 CDS Ecaj_0092 NC_007354.1 144576 145205 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc complement(144576..145205) Ehrlichia canis str. Jake 3617986 YP_302742.1 CDS Ecaj_0093 NC_007354.1 146168 146860 R competence protein F complement(146168..146860) Ehrlichia canis str. Jake 3617987 YP_302743.1 CDS Ecaj_0094 NC_007354.1 146860 148029 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(146860..148029) Ehrlichia canis str. Jake 3617988 YP_302744.1 CDS Ecaj_0095 NC_007354.1 149269 150978 R hypothetical protein complement(149269..150978) Ehrlichia canis str. Jake 3617989 YP_302745.1 CDS Ecaj_0096 NC_007354.1 150988 151572 R hypothetical protein complement(150988..151572) Ehrlichia canis str. Jake 3617990 YP_302746.1 CDS Ecaj_0097 NC_007354.1 151677 152111 R hypothetical protein complement(151677..152111) Ehrlichia canis str. Jake 3617991 YP_302747.1 CDS Ecaj_0098 NC_007354.1 152787 153785 R catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta complement(152787..153785) Ehrlichia canis str. Jake 3617992 YP_302748.1 CDS Ecaj_0099 NC_007354.1 154086 155978 R hypothetical protein complement(154086..155978) Ehrlichia canis str. Jake 3617993 YP_302749.1 CDS Ecaj_0100 NC_007354.1 156156 157589 D microcin-processing peptidase 2 156156..157589 Ehrlichia canis str. Jake 3617995 YP_302750.1 CDS Ecaj_0101 NC_007354.1 158034 159122 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(158034..159122) Ehrlichia canis str. Jake 3618373 YP_302751.1 CDS Ecaj_0102 NC_007354.1 160147 160668 R MECDP- synthase complement(160147..160668) Ehrlichia canis str. Jake 3618374 YP_302752.1 CDS Ecaj_0103 NC_007354.1 161453 162148 R 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(161453..162148) Ehrlichia canis str. Jake 3618375 YP_302753.1 CDS Ecaj_0104 NC_007354.1 163423 164700 D hypothetical protein 163423..164700 Ehrlichia canis str. Jake 3618376 YP_302754.1 CDS Ecaj_0105 NC_007354.1 165017 165520 R 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate(AIR) carboxylase complement(165017..165520) Ehrlichia canis str. Jake 3618377 YP_302755.1 CDS Ecaj_0106 NC_007354.1 165510 165956 R hypothetical protein complement(165510..165956) Ehrlichia canis str. Jake 3618378 YP_302756.1 CDS Ecaj_0107 NC_007354.1 166385 166687 D histone-like DNA-binding protein 166385..166687 Ehrlichia canis str. Jake 3618379 YP_302757.1 CDS Ecaj_0108 NC_007354.1 166700 167074 D MerR family transcriptional regulator 166700..167074 Ehrlichia canis str. Jake 3618380 YP_302758.1 CDS Ecaj_0109 NC_007354.1 167903 168526 D hypothetical protein 167903..168526 Ehrlichia canis str. Jake 3618510 YP_302759.1 CDS Ecaj_0110 NC_007354.1 169101 170102 R tryptophanyl-tRNA synthetase complement(169101..170102) Ehrlichia canis str. Jake 3618511 YP_302760.1 CDS Ecaj_0111 NC_007354.1 170351 170950 R GrpE protein HSP-70 cofactor complement(170351..170950) Ehrlichia canis str. Jake 3618512 YP_302761.1 CDS Ecaj_0112 NC_007354.1 171058 172143 D 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase 171058..172143 Ehrlichia canis str. Jake 3618513 YP_302762.1 CDS Ecaj_0113 NC_007354.1 172519 172932 D major outer membrane protein p19 172519..172932 Ehrlichia canis str. Jake 3618514 YP_302763.1 CDS pyrG NC_007354.1 173373 174989 R CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(173373..174989) Ehrlichia canis str. Jake 3618515 YP_302764.1 CDS secG NC_007354.1 174995 175327 R preprotein translocase subunit SecG complement(174995..175327) Ehrlichia canis str. Jake 3618516 YP_302765.1 CDS Ecaj_0116 NC_007354.1 175648 176577 D Phage integrase, N-terminal SAM- like 175648..176577 Ehrlichia canis str. Jake 3618517 YP_302766.1 CDS Ecaj_0117 NC_007354.1 177198 177878 R ABC transporter complement(177198..177878) Ehrlichia canis str. Jake 3618518 YP_302767.1 CDS Ecaj_0118 NC_007354.1 178681 180972 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 178681..180972 Ehrlichia canis str. Jake 3618519 YP_302768.1 CDS Ecaj_0119 NC_007354.1 181119 183764 D hypothetical protein 181119..183764 Ehrlichia canis str. Jake 3618520 YP_302769.1 CDS Ecaj_0120 NC_007354.1 184817 186283 R apolipoprotein N-acyltransferase complement(184817..186283) Ehrlichia canis str. Jake 3618521 YP_302770.1 CDS Ecaj_0121 NC_007354.1 187066 188541 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 187066..188541 Ehrlichia canis str. Jake 3618522 YP_302771.1 CDS Ecaj_0122 NC_007354.1 188623 188934 R hypothetical protein complement(188623..188934) Ehrlichia canis str. Jake 3618523 YP_302772.1 CDS Ecaj_0123 NC_007354.1 189089 189538 R hypothetical protein complement(189089..189538) Ehrlichia canis str. Jake 3618524 YP_302773.1 CDS Ecaj_0124 NC_007354.1 189559 189858 R putative NADH:ubiquinone oxidoreductase 17.2kD subunit complement(189559..189858) Ehrlichia canis str. Jake 3618525 YP_302774.1 CDS nrdR NC_007354.1 189989 190450 D transcriptional regulator NrdR 189989..190450 Ehrlichia canis str. Jake 3618436 YP_302775.1 CDS Ecaj_0126 NC_007354.1 190710 192725 R hypothetical protein complement(190710..192725) Ehrlichia canis str. Jake 3618438 YP_302776.1 CDS Ecaj_0127 NC_007354.1 193233 196250 D surface protein-like protein 193233..196250 Ehrlichia canis str. Jake 3618439 YP_302777.1 CDS Ecaj_0128 NC_007354.1 196640 197683 D extracellular solute-binding protein 196640..197683 Ehrlichia canis str. Jake 3618440 YP_302778.1 CDS rpsP NC_007354.1 198532 198795 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(198532..198795) Ehrlichia canis str. Jake 3618441 YP_302779.1 CDS Ecaj_0130 NC_007354.1 198987 200312 D general substrate transporter 198987..200312 Ehrlichia canis str. Jake 3618442 YP_302780.1 CDS Ecaj_0131 NC_007354.1 200746 200916 R hypothetical protein complement(200746..200916) Ehrlichia canis str. Jake 3618443 YP_302781.1 CDS Ecaj_0132 NC_007354.1 201810 202505 R short-chain alchohol deydrogenase complement(201810..202505) Ehrlichia canis str. Jake 3618444 YP_302782.1 CDS pheS NC_007354.1 202507 203544 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(202507..203544) Ehrlichia canis str. Jake 3618445 YP_302783.1 CDS rplT NC_007354.1 203531 203905 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(203531..203905) Ehrlichia canis str. Jake 3618446 YP_302784.1 CDS rpmI NC_007354.1 203931 204131 R 50S ribosomal protein L35 complement(203931..204131) Ehrlichia canis str. Jake 3618447 YP_302785.1 CDS Ecaj_0136 NC_007354.1 204483 205124 D hypothetical protein 204483..205124 Ehrlichia canis str. Jake 3618448 YP_302786.1 CDS rho NC_007354.1 205559 206989 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 205559..206989 Ehrlichia canis str. Jake 3618449 YP_302787.1 CDS Ecaj_0138 NC_007354.1 208939 210414 R dihydrolipoamide dehydrogenase complement(208939..210414) Ehrlichia canis str. Jake 3618450 YP_302788.1 CDS Ecaj_0139 NC_007354.1 210619 213003 D hypothetical protein 210619..213003 Ehrlichia canis str. Jake 3618451 YP_302789.1 CDS Ecaj_0140 NC_007354.1 213426 214874 D hypothetical protein 213426..214874 Ehrlichia canis str. Jake 3618452 YP_302790.1 CDS Ecaj_0141 NC_007354.1 214874 215506 D hypothetical protein 214874..215506 Ehrlichia canis str. Jake 3618453 YP_302791.1 CDS Ecaj_0142 NC_007354.1 215496 216032 D hypothetical protein 215496..216032 Ehrlichia canis str. Jake 3618454 YP_302792.1 CDS Ecaj_0143 NC_007354.1 216299 217093 D Beta-lactamase-like 216299..217093 Ehrlichia canis str. Jake 3618286 YP_302793.1 CDS Ecaj_0144 NC_007354.1 217840 218640 R glutamine synthetase complement(217840..218640) Ehrlichia canis str. Jake 3618287 YP_302794.1 CDS Ecaj_0145 NC_007354.1 218647 219771 R binding-protein dependent transport system inner membrane protein complement(218647..219771) Ehrlichia canis str. Jake 3618288 YP_302795.1 CDS alaS NC_007354.1 219915 222590 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 219915..222590 Ehrlichia canis str. Jake 3618289 YP_302796.1 CDS Ecaj_0147 NC_007354.1 224882 225769 R succinyl-CoA synthetase subunit alpha complement(224882..225769) Ehrlichia canis str. Jake 3618290 YP_302797.1 CDS sucC NC_007354.1 225777 226937 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(225777..226937) Ehrlichia canis str. Jake 3618291 YP_302798.1 CDS rpsU NC_007354.1 227018 227293 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(227018..227293) Ehrlichia canis str. Jake 3618292 YP_302799.1 CDS Ecaj_0150 NC_007354.1 227439 228461 R phosphate ABC transporter substrate-binding protein complement(227439..228461) Ehrlichia canis str. Jake 3618293 YP_302800.1 CDS Ecaj_0151 NC_007354.1 228521 229138 R electron transport protein SCO1/SenC complement(228521..229138) Ehrlichia canis str. Jake 3618294 YP_302801.1 CDS Ecaj_0152 NC_007354.1 229443 230480 R 2-nitropropane dioxygenase complement(229443..230480) Ehrlichia canis str. Jake 3618295 YP_302802.1 CDS Ecaj_0153 NC_007354.1 230489 231010 R nickel-dependent hydrogenase b- type cytochrome subunit complement(230489..231010) Ehrlichia canis str. Jake 3618296 YP_302803.1 CDS Ecaj_0154 NC_007354.1 231165 232784 D binding-protein dependent transport system inner membrane protein 231165..232784 Ehrlichia canis str. Jake 3618297 YP_302804.1 CDS Ecaj_0155 NC_007354.1 233991 235508 R Type I secretion membrane fusion protein, HlyD complement(233991..235508) Ehrlichia canis str. Jake 3618298 YP_302805.1 CDS Ecaj_0156 NC_007354.1 235887 236504 R hypothetical protein complement(235887..236504) Ehrlichia canis str. Jake 3618540 YP_302806.1 CDS Ecaj_0157 NC_007354.1 237293 238927 R Beta-lactamase-like complement(237293..238927) Ehrlichia canis str. Jake 3618505 YP_302807.1 CDS Ecaj_0158 NC_007354.1 239591 240886 D metallophosphoesterase 239591..240886 Ehrlichia canis str. Jake 3618140 YP_302808.1 CDS rpsL NC_007354.1 241157 241528 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 241157..241528 Ehrlichia canis str. Jake 3617740 YP_302809.1 CDS Ecaj_0160 NC_007354.1 241544 242026 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 241544..242026 Ehrlichia canis str. Jake 3617741 YP_302810.1 CDS Ecaj_0161 NC_007354.1 242048 244120 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 242048..244120 Ehrlichia canis str. Jake 3617742 YP_302811.1 CDS Ecaj_0162 NC_007354.1 244136 245323 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 244136..245323 Ehrlichia canis str. Jake 3618360 YP_302812.1 CDS secE NC_007354.1 245462 245659 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 245462..245659 Ehrlichia canis str. Jake 3618362 YP_302813.1 CDS Ecaj_0164 NC_007354.1 245649 246194 D transcription antitermination protein NusG 245649..246194 Ehrlichia canis str. Jake 3618363 YP_302814.1 CDS rplK NC_007354.1 246191 246634 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 246191..246634 Ehrlichia canis str. Jake 3618364 YP_302815.1 CDS rplA NC_007354.1 246660 247322 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 246660..247322 Ehrlichia canis str. Jake 3618365 YP_302816.1 CDS rplJ NC_007354.1 247339 247821 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 247339..247821 Ehrlichia canis str. Jake 3618366 YP_302817.1 CDS rplL NC_007354.1 247877 248275 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 247877..248275 Ehrlichia canis str. Jake 3618367 YP_302818.1 CDS rpoB NC_007354.1 248323 252465 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 248323..252465 Ehrlichia canis str. Jake 3618368 YP_302819.1 CDS Ecaj_0170 NC_007354.1 252485 256717 D DNA-directed RNA polymerase 252485..256717 Ehrlichia canis str. Jake 3618369 YP_302820.1 CDS Ecaj_0171 NC_007354.1 257736 258839 D 8-amino-7-oxononanoate synthase 257736..258839 Ehrlichia canis str. Jake 3618370 YP_302821.1 CDS Ecaj_0172 NC_007354.1 259486 259902 D hypothetical protein 259486..259902 Ehrlichia canis str. Jake 3618280 YP_302822.1 CDS rnhB NC_007354.1 260433 261062 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(260433..261062) Ehrlichia canis str. Jake 3618281 YP_302823.1 CDS Ecaj_0174 NC_007354.1 262012 265932 D hypothetical protein 262012..265932 Ehrlichia canis str. Jake 3618282 YP_302824.1 CDS Ecaj_0175 NC_007354.1 266383 266859 R hypothetical protein complement(266383..266859) Ehrlichia canis str. Jake 3618283 YP_302825.1 CDS Ecaj_0176 NC_007354.1 266996 267592 D hypothetical protein 266996..267592 Ehrlichia canis str. Jake 3618284 YP_302826.1 CDS Ecaj_0177 NC_007354.1 268577 269371 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(268577..269371) Ehrlichia canis str. Jake 3618285 YP_302827.1 CDS Ecaj_0178 NC_007354.1 269381 270433 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(269381..270433) Ehrlichia canis str. Jake 3617615 YP_302828.1 CDS Ecaj_0179 NC_007354.1 270596 271180 D formylmethionine deformylase 270596..271180 Ehrlichia canis str. Jake 3617616 YP_302829.1 CDS Ecaj_0180 NC_007354.1 271824 273239 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(271824..273239) Ehrlichia canis str. Jake 3617617 YP_302830.1 CDS Ecaj_0181 NC_007354.1 273597 274238 D phospholipase/carboxylesterase 273597..274238 Ehrlichia canis str. Jake 3617618 YP_302831.1 CDS Ecaj_0182 NC_007354.1 274636 275583 D patatin 274636..275583 Ehrlichia canis str. Jake 3617619 YP_302832.1 CDS Ecaj_0183 NC_007354.1 276018 276611 D pyridoxamine 5'-phosphate oxidase 276018..276611 Ehrlichia canis str. Jake 3617620 YP_302833.1 CDS Ecaj_0184 NC_007354.1 277368 277661 R BolA-like protein complement(277368..277661) Ehrlichia canis str. Jake 3617621 YP_302834.1 CDS Ecaj_0185 NC_007354.1 277934 278749 D hypothetical protein 277934..278749 Ehrlichia canis str. Jake 3617622 YP_302835.1 CDS Ecaj_0186 NC_007354.1 279307 280164 D hypothetical protein 279307..280164 Ehrlichia canis str. Jake 3617623 YP_302836.1 CDS Ecaj_0187 NC_007354.1 280752 284123 D DNA polymerase III subunit alpha 280752..284123 Ehrlichia canis str. Jake 3617624 YP_302837.1 CDS Ecaj_0188 NC_007354.1 284417 285703 D 3-phosphoshikimate 1-carboxyvinyltransferase 284417..285703 Ehrlichia canis str. Jake 3617625 YP_302838.1 CDS Ecaj_0189 NC_007354.1 287591 288001 D succinate dehydrogenase subunit C 287591..288001 Ehrlichia canis str. Jake 3617627 YP_302839.1 CDS Ecaj_0190 NC_007354.1 288016 288372 D succinate dehydrogenase subunit D 288016..288372 Ehrlichia canis str. Jake 3617628 YP_302840.1 CDS Ecaj_0191 NC_007354.1 288595 289860 D hypothetical protein 288595..289860 Ehrlichia canis str. Jake 3617629 YP_302841.1 CDS Ecaj_0192 NC_007354.1 290127 290936 R phosphomethylpyrimidine kinase complement(290127..290936) Ehrlichia canis str. Jake 3617630 YP_302842.1 CDS Ecaj_0193 NC_007354.1 290929 291585 R chromosomal DNA replication initiator-like protein complement(290929..291585) Ehrlichia canis str. Jake 3617631 YP_302843.1 CDS rpsD NC_007354.1 291984 292592 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 291984..292592 Ehrlichia canis str. Jake 3617632 YP_302844.1 CDS Ecaj_0196 NC_007354.1 293905 295026 D hypothetical protein 293905..295026 Ehrlichia canis str. Jake 3617635 YP_302845.1 CDS Ecaj_0197 NC_007354.1 296904 297104 D hypothetical protein 296904..297104 Ehrlichia canis str. Jake 3617636 YP_302846.1 CDS Ecaj_0198 NC_007354.1 297137 298282 R hypothetical protein complement(297137..298282) Ehrlichia canis str. Jake 3617637 YP_302847.1 CDS Ecaj_0199 NC_007354.1 298324 299109 R N-acetyltransferase GCN5 complement(298324..299109) Ehrlichia canis str. Jake 3617638 YP_302848.1 CDS Ecaj_0200 NC_007354.1 299111 299617 R phosphatidylglycerophosphatase A complement(299111..299617) Ehrlichia canis str. Jake 3617639 YP_302849.1 CDS Ecaj_0201 NC_007354.1 300507 301829 D trigger factor 300507..301829 Ehrlichia canis str. Jake 3617642 YP_302850.1 CDS clpP NC_007354.1 301900 302502 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 301900..302502 Ehrlichia canis str. Jake 3617643 YP_302851.1 CDS clpX NC_007354.1 302515 303735 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 302515..303735 Ehrlichia canis str. Jake 3617644 YP_302852.1 CDS Ecaj_0204 NC_007354.1 303745 306150 D Lon-A peptidase 303745..306150 Ehrlichia canis str. Jake 3617645 YP_302853.1 CDS Ecaj_0205 NC_007354.1 307914 308825 D methionyl-tRNA formyltransferase 307914..308825 Ehrlichia canis str. Jake 3617647 YP_302854.1 CDS Ecaj_0206 NC_007354.1 309074 309898 D rhodanese-like protein 309074..309898 Ehrlichia canis str. Jake 3617685 YP_302855.1 CDS Ecaj_0207 NC_007354.1 310419 311240 D hypothetical protein 310419..311240 Ehrlichia canis str. Jake 3617686 YP_302856.1 CDS Ecaj_0208 NC_007354.1 311580 312629 R thiamine monophosphate synthase complement(311580..312629) Ehrlichia canis str. Jake 3617687 YP_302857.1 CDS Ecaj_0210 NC_007354.1 313905 315191 R hypothetical protein complement(313905..315191) Ehrlichia canis str. Jake 3617689 YP_302858.1 CDS Ecaj_0211 NC_007354.1 315330 315614 D hypothetical protein 315330..315614 Ehrlichia canis str. Jake 3617690 YP_302859.1 CDS Ecaj_0212 NC_007354.1 315622 318168 D cell division protein FtsK 315622..318168 Ehrlichia canis str. Jake 3617691 YP_302860.1 CDS Ecaj_0213 NC_007354.1 319716 320702 R hypothetical protein complement(319716..320702) Ehrlichia canis str. Jake 3617692 YP_302861.1 CDS argD NC_007354.1 320826 322001 R DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase protein complement(320826..322001) Ehrlichia canis str. Jake 3617693 YP_302862.1 CDS Ecaj_0215 NC_007354.1 322158 323570 D sensor histidine kinase 322158..323570 Ehrlichia canis str. Jake 3617694 YP_302863.1 CDS mutL NC_007354.1 323844 325892 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 323844..325892 Ehrlichia canis str. Jake 3617695 YP_302864.1 CDS Ecaj_0217 NC_007354.1 327012 328136 R SMF protein complement(327012..328136) Ehrlichia canis str. Jake 3617696 YP_302865.1 CDS Ecaj_0218 NC_007354.1 328362 329630 R 3-oxoacyl-ACP synthase complement(328362..329630) Ehrlichia canis str. Jake 3617697 YP_302866.1 CDS Ecaj_0219 NC_007354.1 329646 329921 R acyl carrier protein complement(329646..329921) Ehrlichia canis str. Jake 3617698 YP_302867.1 CDS Ecaj_0220 NC_007354.1 331084 332469 R hypothetical protein complement(331084..332469) Ehrlichia canis str. Jake 3617699 YP_302868.1 CDS Ecaj_0221 NC_007354.1 332842 335643 D ankyrin 332842..335643 Ehrlichia canis str. Jake 3617700 YP_302869.2 CDS rpmG NC_007354.1 335621 335791 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(335621..335791) Ehrlichia canis str. Jake 3617701 YP_302870.1 CDS Ecaj_0223 NC_007354.1 335965 336672 D hypothetical protein 335965..336672 Ehrlichia canis str. Jake 3617702 YP_302871.1 CDS Ecaj_0224 NC_007354.1 336677 337156 D disulfide bond formation protein DsbB 336677..337156 Ehrlichia canis str. Jake 3617703 YP_302872.1 CDS Ecaj_0225 NC_007354.1 337140 337652 D Coq7 family protein 337140..337652 Ehrlichia canis str. Jake 3617704 YP_302873.1 CDS mnmA NC_007354.1 338795 339898 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(338795..339898) Ehrlichia canis str. Jake 3617648 YP_302874.1 CDS Ecaj_0227 NC_007354.1 340369 341379 R putative Tfp pilus assembly proteinpilusretraction ATPase PilT complement(340369..341379) Ehrlichia canis str. Jake 3617649 YP_302875.1 CDS Ecaj_0228 NC_007354.1 341789 342826 R hypothetical protein complement(341789..342826) Ehrlichia canis str. Jake 3617650 YP_302876.1 CDS Ecaj_0229 NC_007354.1 343048 344112 R hypothetical protein complement(343048..344112) Ehrlichia canis str. Jake 3617894 YP_302877.1 CDS Ecaj_0230 NC_007354.1 344162 345622 R hypothetical protein complement(344162..345622) Ehrlichia canis str. Jake 3618299 YP_302878.1 CDS Ecaj_0231 NC_007354.1 345933 346919 R hypothetical protein complement(345933..346919) Ehrlichia canis str. Jake 3618300 YP_302879.1 CDS Ecaj_0232 NC_007354.1 347891 349129 R hypothetical protein complement(347891..349129) Ehrlichia canis str. Jake 3618301 YP_302880.1 CDS Ecaj_0233 NC_007354.1 349422 351341 R ATP-dependent DNA helicase Rep complement(349422..351341) Ehrlichia canis str. Jake 3618302 YP_302881.1 CDS Ecaj_0234 NC_007354.1 351788 354484 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 351788..354484 Ehrlichia canis str. Jake 3618303 YP_302882.1 CDS Ecaj_0235 NC_007354.1 354502 355140 D DNA-(apurinic or apyrimidinic site) lyase 354502..355140 Ehrlichia canis str. Jake 3618304 YP_302883.1 CDS Ecaj_0236 NC_007354.1 355252 355854 D hypothetical protein 355252..355854 Ehrlichia canis str. Jake 3618305 YP_302884.1 CDS Ecaj_0237 NC_007354.1 355925 357838 D molecular chaperone; heat shock protein 90 355925..357838 Ehrlichia canis str. Jake 3618306 YP_302885.1 CDS Ecaj_0238 NC_007354.1 359333 360634 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(359333..360634) Ehrlichia canis str. Jake 3618307 YP_302886.1 CDS Ecaj_0239 NC_007354.1 361476 364331 R hypothetical protein complement(361476..364331) Ehrlichia canis str. Jake 3618309 YP_302887.1 CDS Ecaj_0240 NC_007354.1 365011 365754 R biotin--acetyl-CoA-carboxylase ligase complement(365011..365754) Ehrlichia canis str. Jake 3618310 YP_302888.1 CDS Ecaj_0241 NC_007354.1 366308 366985 R glutathione S-transferase complement(366308..366985) Ehrlichia canis str. Jake 3618311 YP_302889.1 CDS Ecaj_0242 NC_007354.1 367354 367863 R hypothetical protein complement(367354..367863) Ehrlichia canis str. Jake 3618312 YP_302890.1 CDS Ecaj_0243 NC_007354.1 368171 369193 D ABC transporter 368171..369193 Ehrlichia canis str. Jake 3618333 YP_302891.1 CDS Ecaj_0244 NC_007354.1 369219 369389 D twin-arginine translocation protein TatA/E 369219..369389 Ehrlichia canis str. Jake 3618334 YP_302892.1 CDS recR NC_007354.1 369630 370217 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 369630..370217 Ehrlichia canis str. Jake 3618335 YP_302893.1 CDS Ecaj_0248 NC_007354.1 371058 371921 R periplasmic solute binding protein complement(371058..371921) Ehrlichia canis str. Jake 3618338 YP_302894.1 CDS Ecaj_0249 NC_007354.1 371988 372641 D ABC transporter 371988..372641 Ehrlichia canis str. Jake 3618339 YP_302895.1 CDS Ecaj_0250 NC_007354.1 372634 374076 D 2-octaprenylphenol hydroxylase 372634..374076 Ehrlichia canis str. Jake 3618340 YP_302896.1 CDS Ecaj_0251 NC_007354.1 374860 376065 D major facilitator family transporter 374860..376065 Ehrlichia canis str. Jake 3618341 YP_302897.1 CDS Ecaj_0252 NC_007354.1 377146 378471 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(377146..378471) Ehrlichia canis str. Jake 3618342 YP_302898.1 CDS Ecaj_0253 NC_007354.1 379361 382981 R hypothetical protein complement(379361..382981) Ehrlichia canis str. Jake 3618343 YP_302899.1 CDS Ecaj_0254 NC_007354.1 383839 384648 R hypothetical protein complement(383839..384648) Ehrlichia canis str. Jake 3618344 YP_302900.1 CDS sucA NC_007354.1 385384 388122 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 385384..388122 Ehrlichia canis str. Jake 3618345 YP_302901.1 CDS Ecaj_0256 NC_007354.1 388484 389632 R HK97 family phage major capsid protein complement(388484..389632) Ehrlichia canis str. Jake 3618346 YP_302902.1 CDS Ecaj_0257 NC_007354.1 390168 391058 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(390168..391058) Ehrlichia canis str. Jake 3618347 YP_302903.1 CDS Ecaj_0258 NC_007354.1 391759 392112 R histidine triad (HIT) protein complement(391759..392112) Ehrlichia canis str. Jake 3618348 YP_302904.1 CDS Ecaj_0259 NC_007354.1 392099 393205 R hypothetical protein complement(392099..393205) Ehrlichia canis str. Jake 3618349 YP_302905.1 CDS Ecaj_0260 NC_007354.1 393396 395810 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 393396..395810 Ehrlichia canis str. Jake 3618350 YP_302906.1 CDS Ecaj_0261 NC_007354.1 396969 398486 R NAD+ synthase complement(396969..398486) Ehrlichia canis str. Jake 3618351 YP_302907.1 CDS Ecaj_0262 NC_007354.1 398874 399866 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(398874..399866) Ehrlichia canis str. Jake 3618352 YP_302908.1 CDS Ecaj_0263 NC_007354.1 400081 402816 D hypothetical protein 400081..402816 Ehrlichia canis str. Jake 3618353 YP_302909.1 CDS Ecaj_0264 NC_007354.1 403389 404636 D general substrate transporter 403389..404636 Ehrlichia canis str. Jake 3618354 YP_302910.1 CDS Ecaj_0265 NC_007354.1 405490 406725 D general substrate transporter 405490..406725 Ehrlichia canis str. Jake 3618355 YP_302911.1 CDS Ecaj_0266 NC_007354.1 407640 408113 R single-strand binding protein complement(407640..408113) Ehrlichia canis str. Jake 3618356 YP_302912.1 CDS Ecaj_0267 NC_007354.1 408264 409640 D malonyl-CoA decarboxylase 408264..409640 Ehrlichia canis str. Jake 3617651 YP_302913.1 CDS gatB NC_007354.1 409673 411121 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 409673..411121 Ehrlichia canis str. Jake 3617652 YP_302914.1 CDS Ecaj_0269 NC_007354.1 412352 413194 D enoyl-(acyl carrier protein) reductase 412352..413194 Ehrlichia canis str. Jake 3617654 YP_302915.1 CDS dnaA NC_007354.1 413518 414876 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 413518..414876 Ehrlichia canis str. Jake 3617655 YP_302916.1 CDS Ecaj_0271 NC_007354.1 415695 416684 R hypothetical protein complement(415695..416684) Ehrlichia canis str. Jake 3617656 YP_302917.1 CDS Ecaj_0272 NC_007354.1 417252 417836 D cytidyltransferase-like protein 417252..417836 Ehrlichia canis str. Jake 3617657 YP_302918.1 CDS Ecaj_0273 NC_007354.1 417898 418614 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 417898..418614 Ehrlichia canis str. Jake 3617658 YP_302919.1 CDS Ecaj_0274 NC_007354.1 418611 418895 R histone-like DNA-binding protein complement(418611..418895) Ehrlichia canis str. Jake 3617659 YP_302920.1 CDS Ecaj_0275 NC_007354.1 419237 420127 R ATPase complement(419237..420127) Ehrlichia canis str. Jake 3617660 YP_302921.1 CDS Ecaj_0276 NC_007354.1 420732 421328 R translation factor SUA5 complement(420732..421328) Ehrlichia canis str. Jake 3617661 YP_302922.1 CDS Ecaj_0277 NC_007354.1 421559 422161 D dephospho-CoA kinase 421559..422161 Ehrlichia canis str. Jake 3617662 YP_302923.1 CDS Ecaj_0278 NC_007354.1 423245 424942 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(423245..424942) Ehrlichia canis str. Jake 3617663 YP_302924.1 CDS Ecaj_0279 NC_007354.1 425082 425696 R Smr protein/MutS2 C-terminal complement(425082..425696) Ehrlichia canis str. Jake 3617664 YP_302925.1 CDS Ecaj_0280 NC_007354.1 425785 426201 R RNA polymerase subunit omega complement(425785..426201) Ehrlichia canis str. Jake 3617665 YP_302926.1 CDS Ecaj_0281 NC_007354.1 426290 426616 R hypothetical protein complement(426290..426616) Ehrlichia canis str. Jake 3617666 YP_302927.1 CDS leuS NC_007354.1 427109 429598 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 427109..429598 Ehrlichia canis str. Jake 3617667 YP_302928.1 CDS Ecaj_0283 NC_007354.1 430208 430990 D TatD-related deoxyribonuclease 430208..430990 Ehrlichia canis str. Jake 3617668 YP_302929.1 CDS Ecaj_0284 NC_007354.1 431252 431938 D orotidine-5'-phosphate decarboxylase 431252..431938 Ehrlichia canis str. Jake 3617669 YP_302930.1 CDS Ecaj_0285 NC_007354.1 432275 433045 D 5'-nucleotidase 432275..433045 Ehrlichia canis str. Jake 3617670 YP_302931.1 CDS Ecaj_0286 NC_007354.1 433160 433561 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 433160..433561 Ehrlichia canis str. Jake 3617671 YP_302932.1 CDS Ecaj_0287 NC_007354.1 434052 434630 R NADH (or F420H2) dehydrogenase subunit C complement(434052..434630) Ehrlichia canis str. Jake 3617672 YP_302933.1 CDS Ecaj_0288 NC_007354.1 434945 435502 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(434945..435502) Ehrlichia canis str. Jake 3617673 YP_302934.1 CDS Ecaj_0289 NC_007354.1 435493 435864 R NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 complement(435493..435864) Ehrlichia canis str. Jake 3617674 YP_302935.1 CDS Ecaj_0290 NC_007354.1 436200 439052 R excinuclease ABC subunit A complement(436200..439052) Ehrlichia canis str. Jake 3617675 YP_302936.1 CDS Ecaj_0291 NC_007354.1 439307 439753 R hypothetical protein complement(439307..439753) Ehrlichia canis str. Jake 3617676 YP_302937.1 CDS ribH NC_007354.1 439842 440288 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(439842..440288) Ehrlichia canis str. Jake 3617677 YP_302938.1 CDS Ecaj_0293 NC_007354.1 440290 442029 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC complement(440290..442029) Ehrlichia canis str. Jake 3617678 YP_302939.1 CDS Ecaj_0294 NC_007354.1 442364 443746 R Sodium:alanine symporter complement(442364..443746) Ehrlichia canis str. Jake 3617679 YP_302940.1 CDS Ecaj_0295 NC_007354.1 443768 444547 R CDP-alcohol phosphatidyltransferase complement(443768..444547) Ehrlichia canis str. Jake 3617680 YP_302941.1 CDS Ecaj_0296 NC_007354.1 444557 445237 R catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase complement(444557..445237) Ehrlichia canis str. Jake 3617681 YP_302942.1 CDS Ecaj_0297 NC_007354.1 445901 449293 R hypothetical protein complement(445901..449293) Ehrlichia canis str. Jake 3617682 YP_302943.1 CDS Ecaj_0301 NC_007354.1 450462 451031 D translation elongation factor P (EF-P) 450462..451031 Ehrlichia canis str. Jake 3617723 YP_302944.1 CDS Ecaj_0302 NC_007354.1 451215 451982 D inositol monophosphatase family protein 451215..451982 Ehrlichia canis str. Jake 3617724 YP_302945.1 CDS Ecaj_0303 NC_007354.1 452678 453604 D ribosomal large subunit pseudouridine synthase C 452678..453604 Ehrlichia canis str. Jake 3617725 YP_302946.1 CDS pleD NC_007354.1 454189 455565 R involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD complement(454189..455565) Ehrlichia canis str. Jake 3617726 YP_302947.1 CDS Ecaj_0305 NC_007354.1 455580 455846 R hypothetical protein complement(455580..455846) Ehrlichia canis str. Jake 3617727 YP_302948.1 CDS Ecaj_0306 NC_007354.1 455858 460606 R glutamate dehydrogenase complement(455858..460606) Ehrlichia canis str. Jake 3617728 YP_302949.1 CDS Ecaj_0307 NC_007354.1 461148 461777 D exopolysaccharide synthesis, ExoD 461148..461777 Ehrlichia canis str. Jake 3617729 YP_302950.1 CDS cysS NC_007354.1 461774 463153 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 461774..463153 Ehrlichia canis str. Jake 3617730 YP_302951.1 CDS Ecaj_0309 NC_007354.1 464082 466604 R hypothetical protein complement(464082..466604) Ehrlichia canis str. Jake 3617731 YP_302952.1 CDS nrdF NC_007354.1 466928 467902 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 466928..467902 Ehrlichia canis str. Jake 3617732 YP_302953.1 CDS Ecaj_0311 NC_007354.1 468768 469037 R hypothetical protein complement(468768..469037) Ehrlichia canis str. Jake 3617733 YP_302954.1 CDS Ecaj_0312 NC_007354.1 469042 469608 R hypothetical protein complement(469042..469608) Ehrlichia canis str. Jake 3617734 YP_302955.1 CDS Ecaj_0313 NC_007354.1 469679 470686 D hypothetical protein 469679..470686 Ehrlichia canis str. Jake 3617735 YP_302956.1 CDS Ecaj_0314 NC_007354.1 471248 473062 D DNA primase 471248..473062 Ehrlichia canis str. Jake 3617736 YP_302957.1 CDS Ecaj_0315 NC_007354.1 474557 476425 R RNA polymerase sigma factor rpoD complement(474557..476425) Ehrlichia canis str. Jake 3617737 YP_302958.1 CDS Ecaj_0316 NC_007354.1 476569 477522 R dihydrouridine synthase TIM-barrel protein nifR3 complement(476569..477522) Ehrlichia canis str. Jake 3617738 YP_302959.1 CDS Ecaj_0317 NC_007354.1 477954 478802 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 477954..478802 Ehrlichia canis str. Jake 3617739 YP_302960.1 CDS Ecaj_0318 NC_007354.1 479325 479645 R CutA1 divalent ion tolerance protein complement(479325..479645) Ehrlichia canis str. Jake 3617834 YP_302961.1 CDS Ecaj_0319 NC_007354.1 479754 482228 R response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal complement(479754..482228) Ehrlichia canis str. Jake 3617892 YP_302962.1 CDS Ecaj_0320 NC_007354.1 482362 483021 R O-methyltransferase family protein complement(482362..483021) Ehrlichia canis str. Jake 3617893 YP_302963.1 CDS Ecaj_0321 NC_007354.1 483257 483556 D hypothetical protein 483257..483556 Ehrlichia canis str. Jake 3618010 YP_302964.1 CDS Ecaj_0322 NC_007354.1 483645 485045 D sugar kinase 483645..485045 Ehrlichia canis str. Jake 3618011 YP_302965.1 CDS Ecaj_0323 NC_007354.1 485455 487917 D DNA topoisomerase I 485455..487917 Ehrlichia canis str. Jake 3618012 YP_302966.1 CDS Ecaj_0324 NC_007354.1 487980 488333 R hypothetical protein complement(487980..488333) Ehrlichia canis str. Jake 3618013 YP_302967.1 CDS Ecaj_0325 NC_007354.1 488503 488976 R hypothetical protein complement(488503..488976) Ehrlichia canis str. Jake 3618014 YP_302968.1 CDS acpS NC_007354.1 490470 490850 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(490470..490850) Ehrlichia canis str. Jake 3618017 YP_302969.1 CDS Ecaj_0327 NC_007354.1 490847 492121 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(490847..492121) Ehrlichia canis str. Jake 3618018 YP_302970.1 CDS Ecaj_0328 NC_007354.1 493135 494100 R hypothetical protein complement(493135..494100) Ehrlichia canis str. Jake 3618019 YP_302971.1 CDS coaD NC_007354.1 494436 494924 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 494436..494924 Ehrlichia canis str. Jake 3618021 YP_302972.1 CDS Ecaj_0331 NC_007354.1 496308 497273 R thioredoxin reductase complement(496308..497273) Ehrlichia canis str. Jake 3618023 YP_302973.1 CDS Ecaj_0332 NC_007354.1 497274 497891 R alkyl hydroperoxide reductase/thiol specific antioxidant/ Mal allergen complement(497274..497891) Ehrlichia canis str. Jake 3618024 YP_302974.1 CDS Ecaj_0333 NC_007354.1 498313 499509 D aminotransferase 498313..499509 Ehrlichia canis str. Jake 3618183 YP_302975.1 CDS Ecaj_0334 NC_007354.1 500883 502775 R PpiC-type peptidyl-prolyl cis-trans isomerase complement(500883..502775) Ehrlichia canis str. Jake 3618184 YP_302976.1 CDS Ecaj_0335 NC_007354.1 502999 503577 R peptidase M22, glycoprotease complement(502999..503577) Ehrlichia canis str. Jake 3618185 YP_302977.1 CDS Ecaj_0336 NC_007354.1 504476 505381 D tRNA pseudouridine synthase B 504476..505381 Ehrlichia canis str. Jake 3618187 YP_302978.1 CDS rpsO NC_007354.1 505384 505665 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 505384..505665 Ehrlichia canis str. Jake 3618188 YP_302979.1 CDS Ecaj_0338 NC_007354.1 505704 508094 D polynucleotide phosphorylase/polyadenylase 505704..508094 Ehrlichia canis str. Jake 3618189 YP_302980.1 CDS Ecaj_0339 NC_007354.1 508121 508912 D hypothetical protein 508121..508912 Ehrlichia canis str. Jake 3618190 YP_302981.1 CDS Ecaj_0340 NC_007354.1 508942 510738 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 508942..510738 Ehrlichia canis str. Jake 3618191 YP_302982.1 CDS Ecaj_0341 NC_007354.1 511037 511609 D hypothetical protein 511037..511609 Ehrlichia canis str. Jake 3618192 YP_302983.1 CDS Ecaj_0342 NC_007354.1 512383 513036 D hypothetical protein 512383..513036 Ehrlichia canis str. Jake 3618193 YP_302984.1 CDS Ecaj_0343 NC_007354.1 513217 513762 D hypothetical protein 513217..513762 Ehrlichia canis str. Jake 3618194 YP_302985.1 CDS Ecaj_0344 NC_007354.1 514283 516562 D hypothetical protein 514283..516562 Ehrlichia canis str. Jake 3618195 YP_302986.1 CDS Ecaj_0345 NC_007354.1 516944 518839 D hypothetical protein 516944..518839 Ehrlichia canis str. Jake 3618196 YP_302987.1 CDS Ecaj_0346 NC_007354.1 518954 520510 D hypothetical protein 518954..520510 Ehrlichia canis str. Jake 3618197 YP_302988.1 CDS Ecaj_0347 NC_007354.1 521551 522615 D hypothetical protein 521551..522615 Ehrlichia canis str. Jake 3618198 YP_302989.1 CDS Ecaj_0348 NC_007354.1 522890 524497 D hypothetical protein 522890..524497 Ehrlichia canis str. Jake 3618199 YP_302990.1 CDS Ecaj_0349 NC_007354.1 524544 524870 D hypothetical protein 524544..524870 Ehrlichia canis str. Jake 3618200 YP_302991.1 CDS Ecaj_0350 NC_007354.1 525474 526481 R peptide chain release factor 2 complement(525474..526481) Ehrlichia canis str. Jake 3617786 YP_302992.1 CDS Ecaj_0351 NC_007354.1 526886 527632 R hypothetical protein complement(526886..527632) Ehrlichia canis str. Jake 3617787 YP_302993.1 CDS gatA NC_007354.1 527647 529149 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(527647..529149) Ehrlichia canis str. Jake 3617788 YP_302994.1 CDS Ecaj_0353 NC_007354.1 529505 530809 D folylpolyglutamate synthetase 529505..530809 Ehrlichia canis str. Jake 3617789 YP_302995.1 CDS hemC NC_007354.1 531265 532161 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 531265..532161 Ehrlichia canis str. Jake 3617790 YP_302996.1 CDS Ecaj_0355 NC_007354.1 532987 533613 D hypothetical protein 532987..533613 Ehrlichia canis str. Jake 3617791 YP_302997.1 CDS Ecaj_0356 NC_007354.1 533583 533840 D hypothetical protein 533583..533840 Ehrlichia canis str. Jake 3617792 YP_302998.1 CDS Ecaj_0357 NC_007354.1 534865 535542 D hypothetical protein 534865..535542 Ehrlichia canis str. Jake 3617793 YP_302999.1 CDS Ecaj_0358 NC_007354.1 537117 537857 D hypothetical protein 537117..537857 Ehrlichia canis str. Jake 3617794 YP_303000.1 CDS Ecaj_0359 NC_007354.1 538216 540060 D GTP-binding protein TypA 538216..540060 Ehrlichia canis str. Jake 3617795 YP_303001.1 CDS Ecaj_0360 NC_007354.1 540232 540582 D hypothetical protein 540232..540582 Ehrlichia canis str. Jake 3617796 YP_303002.1 CDS Ecaj_0361 NC_007354.1 540615 541118 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(540615..541118) Ehrlichia canis str. Jake 3617797 YP_303003.1 CDS Ecaj_0362 NC_007354.1 541126 541836 R signal peptidase I complement(541126..541836) Ehrlichia canis str. Jake 3617798 YP_303004.1 CDS Ecaj_0363 NC_007354.1 541851 542306 R HesB/YadR/YfhF complement(541851..542306) Ehrlichia canis str. Jake 3617799 YP_303005.1 CDS Ecaj_0364 NC_007354.1 542377 543570 D deoxyguanosinetriphosphate triphosphohydrolase 542377..543570 Ehrlichia canis str. Jake 3617800 YP_303006.1 CDS Ecaj_0365 NC_007354.1 543799 548064 D gp200 543799..548064 Ehrlichia canis str. Jake 3617801 YP_303007.1 CDS Ecaj_0366 NC_007354.1 548982 549809 D hypothetical protein 548982..549809 Ehrlichia canis str. Jake 3617803 YP_303008.1 CDS Ecaj_0367 NC_007354.1 550924 552105 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(550924..552105) Ehrlichia canis str. Jake 3617804 YP_303009.1 CDS Ecaj_0368 NC_007354.1 552258 552938 D hypothetical protein 552258..552938 Ehrlichia canis str. Jake 3617824 YP_303010.1 CDS Ecaj_0369 NC_007354.1 553246 553938 D hypothetical protein 553246..553938 Ehrlichia canis str. Jake 3617825 YP_303011.1 CDS argJ NC_007354.1 554190 555461 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 554190..555461 Ehrlichia canis str. Jake 3617826 YP_303012.1 CDS Ecaj_0371 NC_007354.1 555483 556322 D exodeoxyribonuclease III 555483..556322 Ehrlichia canis str. Jake 3617827 YP_303013.1 CDS Ecaj_0372 NC_007354.1 556836 557612 R hypothetical protein complement(556836..557612) Ehrlichia canis str. Jake 3617828 YP_303014.1 CDS Ecaj_0373 NC_007354.1 557918 558715 R hypothetical protein complement(557918..558715) Ehrlichia canis str. Jake 3617560 YP_303015.1 CDS Ecaj_0374 NC_007354.1 558729 559463 R 3-oxoacyl-ACP reductase complement(558729..559463) Ehrlichia canis str. Jake 3617561 YP_303016.1 CDS Ecaj_0375 NC_007354.1 560097 563246 D proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 560097..563246 Ehrlichia canis str. Jake 3617562 YP_303017.1 CDS Ecaj_0376 NC_007354.1 563778 565064 D aminotransferase 563778..565064 Ehrlichia canis str. Jake 3617563 YP_303018.1 CDS Ecaj_0377 NC_007354.1 566033 567442 R phage protein complement(566033..567442) Ehrlichia canis str. Jake 3617564 YP_303019.1 CDS Ecaj_0378 NC_007354.1 567561 568190 R hypothetical protein complement(567561..568190) Ehrlichia canis str. Jake 3617565 YP_303020.1 CDS Ecaj_0379 NC_007354.1 568332 568880 R hypothetical protein complement(568332..568880) Ehrlichia canis str. Jake 3617566 YP_303021.1 CDS Ecaj_0380 NC_007354.1 568954 569343 R hypothetical protein complement(568954..569343) Ehrlichia canis str. Jake 3617567 YP_303022.1 CDS Ecaj_0382 NC_007354.1 569321 569725 R hypothetical protein complement(569321..569725) Ehrlichia canis str. Jake 3617568 YP_303023.1 CDS Ecaj_0381 NC_007354.1 569722 570276 R phage protein complement(569722..570276) Ehrlichia canis str. Jake 3617569 YP_303024.1 CDS Ecaj_0383 NC_007354.1 570325 570675 R hypothetical protein complement(570325..570675) Ehrlichia canis str. Jake 3617570 YP_303025.1 CDS rpmJ NC_007354.1 571207 571335 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 571207..571335 Ehrlichia canis str. Jake 3617597 YP_303026.1 CDS Ecaj_0385 NC_007354.1 571776 572678 R sigma-70 region 2:sigma-70 region 4 complement(571776..572678) Ehrlichia canis str. Jake 3617598 YP_303027.1 CDS Ecaj_0386 NC_007354.1 572779 573372 D sigma 54 modulation protein/ribosomal protein S30EA 572779..573372 Ehrlichia canis str. Jake 3617599 YP_303028.1 CDS Ecaj_0387 NC_007354.1 573594 586331 D ankyrin 573594..586331 Ehrlichia canis str. Jake 3617600 YP_303029.1 CDS Ecaj_0388 NC_007354.1 586429 587274 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 586429..587274 Ehrlichia canis str. Jake 3617601 YP_303030.1 CDS Ecaj_0389 NC_007354.1 587287 587859 D GTP cyclohydrolase 587287..587859 Ehrlichia canis str. Jake 3617602 YP_303031.1 CDS Ecaj_0390 NC_007354.1 587872 589206 D microcin-processing peptidase 1 587872..589206 Ehrlichia canis str. Jake 3617603 YP_303032.1 CDS Ecaj_0391 NC_007354.1 589804 590820 R FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(589804..590820) Ehrlichia canis str. Jake 3617604 YP_303033.1 CDS ksgA NC_007354.1 591138 591926 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(591138..591926) Ehrlichia canis str. Jake 3617605 YP_303034.1 CDS Ecaj_0393 NC_007354.1 592096 592863 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 592096..592863 Ehrlichia canis str. Jake 3617607 YP_303035.1 CDS Ecaj_0394 NC_007354.1 592863 593843 D putative immunogenic protein 592863..593843 Ehrlichia canis str. Jake 3617608 YP_303036.1 CDS Ecaj_0395 NC_007354.1 593857 594909 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 593857..594909 Ehrlichia canis str. Jake 3617609 YP_303037.1 CDS Ecaj_0396 NC_007354.1 595982 596572 R hypothetical protein complement(595982..596572) Ehrlichia canis str. Jake 3617610 YP_303038.1 CDS Ecaj_0397 NC_007354.1 596767 597123 D dihydroneopterin aldolase 596767..597123 Ehrlichia canis str. Jake 3617611 YP_303039.1 CDS Ecaj_0398 NC_007354.1 597186 598127 D Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 597186..598127 Ehrlichia canis str. Jake 3617612 YP_303040.1 CDS Ecaj_0399 NC_007354.1 598334 599293 D hypothetical protein 598334..599293 Ehrlichia canis str. Jake 3617613 YP_303041.1 CDS Ecaj_0400 NC_007354.1 599789 600019 R hypothetical protein complement(599789..600019) Ehrlichia canis str. Jake 3617614 YP_303042.1 CDS Ecaj_0401 NC_007354.1 600164 600613 D ribose/galactose isomerase 600164..600613 Ehrlichia canis str. Jake 3618382 YP_303043.1 CDS Ecaj_0402 NC_007354.1 600610 601329 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 600610..601329 Ehrlichia canis str. Jake 3618383 YP_303044.1 CDS Ecaj_0403 NC_007354.1 601469 601867 R cytochrome c-type biogenesis protein CcmH complement(601469..601867) Ehrlichia canis str. Jake 3618384 YP_303045.1 CDS Ecaj_0404 NC_007354.1 601851 602924 R hypothetical protein complement(601851..602924) Ehrlichia canis str. Jake 3618385 YP_303046.1 CDS Ecaj_0405 NC_007354.1 602939 603289 R ferredoxin complement(602939..603289) Ehrlichia canis str. Jake 3618386 YP_303047.1 CDS Ecaj_0406 NC_007354.1 603317 605173 R heat shock protein Hsp70 complement(603317..605173) Ehrlichia canis str. Jake 3618387 YP_303048.1 CDS Ecaj_0407 NC_007354.1 605173 605610 R heat shock protein DnaJ, N-terminal complement(605173..605610) Ehrlichia canis str. Jake 3618388 YP_303049.1 CDS Ecaj_0408 NC_007354.1 605603 606028 R HesB/YadR/YfhF complement(605603..606028) Ehrlichia canis str. Jake 3618389 YP_303050.1 CDS Ecaj_0409 NC_007354.1 606059 606475 R scaffold protein complement(606059..606475) Ehrlichia canis str. Jake 3618390 YP_303051.1 CDS Ecaj_0410 NC_007354.1 606511 607779 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(606511..607779) Ehrlichia canis str. Jake 3618391 YP_303052.1 CDS Ecaj_0411 NC_007354.1 607810 609411 R BadM/Rrf2 family transcriptional regulator complement(607810..609411) Ehrlichia canis str. Jake 3618539 YP_303053.1 CDS Ecaj_0412 NC_007354.1 609733 610458 D hypothetical protein 609733..610458 Ehrlichia canis str. Jake 3618485 YP_303054.1 CDS lysK NC_007354.1 610782 612317 D class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 610782..612317 Ehrlichia canis str. Jake 3618486 YP_303055.1 CDS Ecaj_0414 NC_007354.1 612435 612872 D hypothetical protein 612435..612872 Ehrlichia canis str. Jake 3618487 YP_303056.1 CDS Ecaj_0415 NC_007354.1 615106 615708 D hypothetical protein 615106..615708 Ehrlichia canis str. Jake 3618488 YP_303057.1 CDS Ecaj_0416 NC_007354.1 617223 617747 D hypothetical protein 617223..617747 Ehrlichia canis str. Jake 3618489 YP_303058.1 CDS Ecaj_0417 NC_007354.1 618487 620883 R DNA gyrase subunit B complement(618487..620883) Ehrlichia canis str. Jake 3618490 YP_303059.1 CDS pyrB NC_007354.1 621197 622114 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 621197..622114 Ehrlichia canis str. Jake 3618491 YP_303060.1 CDS truA NC_007354.1 622104 622841 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 622104..622841 Ehrlichia canis str. Jake 3617557 YP_303061.1 CDS Ecaj_0420 NC_007354.1 623809 624027 D hypothetical protein 623809..624027 Ehrlichia canis str. Jake 3617767 YP_303062.1 CDS Ecaj_0421 NC_007354.1 624037 626088 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 624037..626088 Ehrlichia canis str. Jake 3617768 YP_303063.1 CDS Ecaj_0422 NC_007354.1 626095 627204 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 626095..627204 Ehrlichia canis str. Jake 3617769 YP_303064.1 CDS Ecaj_0423 NC_007354.1 627570 628343 D hypothetical protein 627570..628343 Ehrlichia canis str. Jake 3617770 YP_303065.1 CDS Ecaj_0425 NC_007354.1 628987 629226 D hypothetical protein 628987..629226 Ehrlichia canis str. Jake 3617771 YP_303066.1 CDS Ecaj_0426 NC_007354.1 630695 631876 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 630695..631876 Ehrlichia canis str. Jake 3617772 YP_303067.1 CDS Ecaj_0427 NC_007354.1 631883 632425 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 631883..632425 Ehrlichia canis str. Jake 3617773 YP_303068.1 CDS Ecaj_0428 NC_007354.1 634633 635505 R hypothetical protein complement(634633..635505) Ehrlichia canis str. Jake 3617774 YP_303069.1 CDS Ecaj_0429 NC_007354.1 635651 636406 R hypothetical protein complement(635651..636406) Ehrlichia canis str. Jake 3617775 YP_303070.1 CDS Ecaj_0430 NC_007354.1 636510 637061 R hypothetical protein complement(636510..637061) Ehrlichia canis str. Jake 3617776 YP_303071.1 CDS Ecaj_0431 NC_007354.1 637246 638556 R hypothetical protein complement(637246..638556) Ehrlichia canis str. Jake 3617777 YP_303072.1 CDS gltX NC_007354.1 638995 640404 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(638995..640404) Ehrlichia canis str. Jake 3617778 YP_303073.1 CDS Ecaj_0433 NC_007354.1 641516 641896 D hypothetical protein 641516..641896 Ehrlichia canis str. Jake 3617780 YP_303074.1 CDS Ecaj_0434 NC_007354.1 642521 643192 D hypothetical protein 642521..643192 Ehrlichia canis str. Jake 3617781 YP_303075.1 CDS Ecaj_0435 NC_007354.1 643546 644133 D hypothetical protein 643546..644133 Ehrlichia canis str. Jake 3617782 YP_303076.1 CDS Ecaj_0436 NC_007354.1 644426 645013 D hypothetical protein 644426..645013 Ehrlichia canis str. Jake 3617783 YP_303077.1 CDS Ecaj_0437 NC_007354.1 645165 646694 D carboxyl transferase 645165..646694 Ehrlichia canis str. Jake 3617784 YP_303078.1 CDS Ecaj_0438 NC_007354.1 646967 647569 R hypothetical protein complement(646967..647569) Ehrlichia canis str. Jake 3617785 YP_303079.1 CDS Ecaj_0440 NC_007354.1 648564 649085 D class I peptide chain release factor domain-containing protein 648564..649085 Ehrlichia canis str. Jake 3618045 YP_303080.1 CDS prfA NC_007354.1 649672 650751 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(649672..650751) Ehrlichia canis str. Jake 3618047 YP_303081.1 CDS engB NC_007354.1 650919 651521 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 650919..651521 Ehrlichia canis str. Jake 3618048 YP_303082.1 CDS Ecaj_0444 NC_007354.1 651493 652464 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 651493..652464 Ehrlichia canis str. Jake 3618049 YP_303083.1 CDS Ecaj_0445 NC_007354.1 652756 653904 D hypothetical protein 652756..653904 Ehrlichia canis str. Jake 3618050 YP_303084.1 CDS Ecaj_0446 NC_007354.1 654126 654974 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 654126..654974 Ehrlichia canis str. Jake 3618051 YP_303085.1 CDS Ecaj_0447 NC_007354.1 655678 656991 R hypothetical protein complement(655678..656991) Ehrlichia canis str. Jake 3618052 YP_303086.1 CDS Ecaj_0448 NC_007354.1 657839 658522 R type IV secretory pathway, VirB3-like complement(657839..658522) Ehrlichia canis str. Jake 3618053 YP_303087.1 CDS Ecaj_0449 NC_007354.1 658740 660020 D Sodium:dicarboxylate symporter 658740..660020 Ehrlichia canis str. Jake 3618054 YP_303088.1 CDS Ecaj_0450 NC_007354.1 660601 661593 R hypothetical protein complement(660601..661593) Ehrlichia canis str. Jake 3618055 YP_303089.1 CDS Ecaj_0454 NC_007354.1 662546 663817 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(662546..663817) Ehrlichia canis str. Jake 3618059 YP_303090.1 CDS Ecaj_0455 NC_007354.1 663898 665121 R putative 3-hydroxyacyl-CoA dehydrogenase complement(663898..665121) Ehrlichia canis str. Jake 3618060 YP_303091.1 CDS Ecaj_0456 NC_007354.1 665203 665664 R hypothetical protein complement(665203..665664) Ehrlichia canis str. Jake 3618061 YP_303092.1 CDS Ecaj_0457 NC_007354.1 665786 666688 D tRNA isopentenyl transferase 665786..666688 Ehrlichia canis str. Jake 3618062 YP_303093.1 CDS Ecaj_0458 NC_007354.1 667238 668608 R divalent cation transporter complement(667238..668608) Ehrlichia canis str. Jake 3618025 YP_303094.1 CDS Ecaj_0459 NC_007354.1 669000 670523 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 669000..670523 Ehrlichia canis str. Jake 3618027 YP_303095.1 CDS Ecaj_0460 NC_007354.1 670523 670909 D H+-transporting two-sector ATPase, delta/epsilon subunit 670523..670909 Ehrlichia canis str. Jake 3618028 YP_303096.1 CDS Ecaj_0461 NC_007354.1 670916 671578 D similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 670916..671578 Ehrlichia canis str. Jake 3618029 YP_303097.1 CDS Ecaj_0462 NC_007354.1 671883 672164 D hypothetical protein 671883..672164 Ehrlichia canis str. Jake 3618030 YP_303098.1 CDS Ecaj_0463 NC_007354.1 673070 677056 R hypothetical protein complement(673070..677056) Ehrlichia canis str. Jake 3618031 YP_303099.1 CDS Ecaj_0464 NC_007354.1 677230 679509 R ATP-dependent Clp protease complement(677230..679509) Ehrlichia canis str. Jake 3618032 YP_303100.1 CDS Ecaj_0465 NC_007354.1 679680 680363 D TerC family integral membrane protein 679680..680363 Ehrlichia canis str. Jake 3618033 YP_303101.1 CDS Ecaj_0466 NC_007354.1 680389 680736 R ribosome-binding factor A complement(680389..680736) Ehrlichia canis str. Jake 3618034 YP_303102.1 CDS infB NC_007354.1 680733 683279 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(680733..683279) Ehrlichia canis str. Jake 3618035 YP_303103.1 CDS nusA NC_007354.1 683303 684856 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(683303..684856) Ehrlichia canis str. Jake 3618036 YP_303104.1 CDS Ecaj_0469 NC_007354.1 685003 688119 R acriflavin resistance protein complement(685003..688119) Ehrlichia canis str. Jake 3618037 YP_303105.1 CDS Ecaj_0470 NC_007354.1 688203 688955 R twin-arginine translocating C- subunit complement(688203..688955) Ehrlichia canis str. Jake 3618038 YP_303106.1 CDS ispG NC_007354.1 688979 690247 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(688979..690247) Ehrlichia canis str. Jake 3618039 YP_303107.1 CDS Ecaj_0472 NC_007354.1 690336 692261 R hypothetical protein complement(690336..692261) Ehrlichia canis str. Jake 3618040 YP_303108.1 CDS Ecaj_0473 NC_007354.1 692522 693685 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(692522..693685) Ehrlichia canis str. Jake 3618041 YP_303109.1 CDS Ecaj_0474 NC_007354.1 693737 695161 R proton-translocating NADH-quinoneoxidoreductase, chain N complement(693737..695161) Ehrlichia canis str. Jake 3618042 YP_303110.1 CDS Ecaj_0475 NC_007354.1 695179 696636 R proton-translocating NADH-quinoneoxidoreductase, chain M complement(695179..696636) Ehrlichia canis str. Jake 3618043 YP_303111.1 CDS Ecaj_0476 NC_007354.1 696642 698507 R NADH-plastoquinone oxidoreductase, chain 5 complement(696642..698507) Ehrlichia canis str. Jake 3618275 YP_303112.1 CDS Ecaj_0477 NC_007354.1 698591 698917 R NADH-ubiquinone oxidoreductase, chain 4L complement(698591..698917) Ehrlichia canis str. Jake 3618276 YP_303113.1 CDS Ecaj_0478 NC_007354.1 698901 699503 R NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 complement(698901..699503) Ehrlichia canis str. Jake 3618277 YP_303114.1 CDS Ecaj_0479 NC_007354.1 699863 700444 R hypothetical protein complement(699863..700444) Ehrlichia canis str. Jake 3618278 YP_303115.1 CDS Ecaj_0480 NC_007354.1 700570 701187 R hypothetical protein complement(700570..701187) Ehrlichia canis str. Jake 3617830 YP_303116.1 CDS Ecaj_0481 NC_007354.1 703345 703854 R hypothetical protein complement(703345..703854) Ehrlichia canis str. Jake 3618372 YP_303117.1 CDS Ecaj_0482 NC_007354.1 704712 704990 R hypothetical protein complement(704712..704990) Ehrlichia canis str. Jake 3617895 YP_303118.1 CDS Ecaj_0483 NC_007354.1 705049 705318 R hypothetical protein complement(705049..705318) Ehrlichia canis str. Jake 3618495 YP_303119.1 CDS Ecaj_0484 NC_007354.1 706214 706810 R hypothetical protein complement(706214..706810) Ehrlichia canis str. Jake 3618496 YP_303120.1 CDS Ecaj_0485 NC_007354.1 708421 709023 R hypothetical protein complement(708421..709023) Ehrlichia canis str. Jake 3618497 YP_303121.1 CDS Ecaj_0486 NC_007354.1 709313 710596 R part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(709313..710596) Ehrlichia canis str. Jake 3618479 YP_303122.1 CDS rpmA NC_007354.1 710834 711100 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(710834..711100) Ehrlichia canis str. Jake 3618481 YP_303123.1 CDS rplU NC_007354.1 711106 711414 R 50S ribosomal protein L21 complement(711106..711414) Ehrlichia canis str. Jake 3618482 YP_303124.1 CDS eno NC_007354.1 711604 712869 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 711604..712869 Ehrlichia canis str. Jake 3618483 YP_303125.1 CDS obgE NC_007354.1 712866 713888 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 712866..713888 Ehrlichia canis str. Jake 3618484 YP_303126.1 CDS mraW NC_007354.1 715081 715974 R S-adenosyl-methyltransferase MraW complement(715081..715974) Ehrlichia canis str. Jake 3618371 YP_303127.1 CDS Ecaj_0492 NC_007354.1 716262 716783 R 5-formyltetrahydrofolate cyclo-ligase complement(716262..716783) Ehrlichia canis str. Jake 3618498 YP_303128.1 CDS Ecaj_0493 NC_007354.1 716788 717507 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(716788..717507) Ehrlichia canis str. Jake 3618201 YP_303129.1 CDS Ecaj_0494 NC_007354.1 717523 717966 R alkyl hydroperoxide reductase/thiol specific antioxidant/ Mal allergen complement(717523..717966) Ehrlichia canis str. Jake 3618202 YP_303130.2 CDS ileS NC_007354.1 718108 721431 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 718108..721431 Ehrlichia canis str. Jake 3618203 YP_303131.1 CDS Ecaj_0496 NC_007354.1 722561 722857 D hypothetical protein 722561..722857 Ehrlichia canis str. Jake 3618204 YP_303132.1 CDS argS NC_007354.1 723565 725295 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(723565..725295) Ehrlichia canis str. Jake 3618507 YP_303133.2 CDS recO NC_007354.1 725639 726373 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 725639..726373 Ehrlichia canis str. Jake 3617996 YP_303134.1 CDS Ecaj_0500 NC_007354.1 726573 727130 D hypothetical protein 726573..727130 Ehrlichia canis str. Jake 3617997 YP_303135.1 CDS Ecaj_0501 NC_007354.1 728080 728595 D ribosomal RNA methyl transferase RrmJ/FtsJ 728080..728595 Ehrlichia canis str. Jake 3617999 YP_303136.1 CDS Ecaj_0502 NC_007354.1 728792 730312 D Mg chelatase-like protein 728792..730312 Ehrlichia canis str. Jake 3618000 YP_303137.1 CDS Ecaj_0503 NC_007354.1 730420 730752 D hypothetical protein 730420..730752 Ehrlichia canis str. Jake 3618001 YP_303138.1 CDS Ecaj_0504 NC_007354.1 730872 731711 R ribonuclease BN complement(730872..731711) Ehrlichia canis str. Jake 3618002 YP_303139.1 CDS Ecaj_0505 NC_007354.1 731875 732819 D thiamine-monophosphate kinase 731875..732819 Ehrlichia canis str. Jake 3618003 YP_303140.1 CDS Ecaj_0506 NC_007354.1 732997 733716 R DNA polymerase III subunit epsilon complement(732997..733716) Ehrlichia canis str. Jake 3618004 YP_303141.1 CDS Ecaj_0507 NC_007354.1 733957 735429 R hypothetical protein complement(733957..735429) Ehrlichia canis str. Jake 3618005 YP_303142.1 CDS Ecaj_0508 NC_007354.1 735867 737822 R hypothetical protein complement(735867..737822) Ehrlichia canis str. Jake 3618006 YP_303143.1 CDS Ecaj_0509 NC_007354.1 739127 740743 R hypothetical protein complement(739127..740743) Ehrlichia canis str. Jake 3618007 YP_303144.1 CDS Ecaj_0510 NC_007354.1 741167 741922 R cytochrome c1 complement(741167..741922) Ehrlichia canis str. Jake 3618008 YP_303145.1 CDS Ecaj_0511 NC_007354.1 741922 743148 R cytochrome b/b6 complement(741922..743148) Ehrlichia canis str. Jake 3618009 YP_303146.1 CDS Ecaj_0512 NC_007354.1 743173 743736 R ubiquinol-cytochrome c reductase, iron-sulfur subunit complement(743173..743736) Ehrlichia canis str. Jake 3618145 YP_303147.1 CDS Ecaj_0513 NC_007354.1 744219 745091 R hypothetical protein complement(744219..745091) Ehrlichia canis str. Jake 3618146 YP_303148.1 CDS Ecaj_0514 NC_007354.1 745188 745991 R ABC transporter complement(745188..745991) Ehrlichia canis str. Jake 3618147 YP_303149.1 CDS Ecaj_0515 NC_007354.1 745998 746360 R hypothetical protein complement(745998..746360) Ehrlichia canis str. Jake 3618148 YP_303150.1 CDS tsf NC_007354.1 746686 747552 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(746686..747552) Ehrlichia canis str. Jake 3618149 YP_303151.1 CDS rpsB NC_007354.1 747542 748417 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(747542..748417) Ehrlichia canis str. Jake 3618150 YP_303152.1 CDS Ecaj_0518 NC_007354.1 749077 749655 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(749077..749655) Ehrlichia canis str. Jake 3618151 YP_303153.1 CDS Ecaj_0519 NC_007354.1 749648 749896 R translation initiation factor 1 complement(749648..749896) Ehrlichia canis str. Jake 3618152 YP_303154.1 CDS Ecaj_0520 NC_007354.1 750009 751079 R secretion protein HlyD complement(750009..751079) Ehrlichia canis str. Jake 3618153 YP_303155.1 CDS Ecaj_0521 NC_007354.1 751098 752498 R dihydrolipoamide dehydrogenase complement(751098..752498) Ehrlichia canis str. Jake 3618154 YP_303156.1 CDS Ecaj_0522 NC_007354.1 752522 753685 R quinoprotein complement(752522..753685) Ehrlichia canis str. Jake 3618155 YP_303157.1 CDS Ecaj_0523 NC_007354.1 754259 755764 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 754259..755764 Ehrlichia canis str. Jake 3618156 YP_303158.1 CDS engA NC_007354.1 756740 758059 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(756740..758059) Ehrlichia canis str. Jake 3618157 YP_303159.1 CDS Ecaj_0525 NC_007354.1 758290 759405 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 758290..759405 Ehrlichia canis str. Jake 3618158 YP_303160.1 CDS ispH NC_007354.1 759707 760666 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 759707..760666 Ehrlichia canis str. Jake 3618159 YP_303161.1 CDS Ecaj_0527 NC_007354.1 760813 761274 D deoxyuridine 5'-triphosphate nucleotidohydrolase 760813..761274 Ehrlichia canis str. Jake 3618160 YP_303162.1 CDS Ecaj_0528 NC_007354.1 761965 762564 D hypothetical protein 761965..762564 Ehrlichia canis str. Jake 3618161 YP_303163.1 CDS Ecaj_0529 NC_007354.1 762770 768862 R putative Type IV secretory pathway VirB6 components complement(762770..768862) Ehrlichia canis str. Jake 3618162 YP_303164.1 CDS Ecaj_0530 NC_007354.1 768899 773233 R TrbL/VirB6 plasmid conjugal transfer protein complement(768899..773233) Ehrlichia canis str. Jake 3618163 YP_303165.1 CDS Ecaj_0531 NC_007354.1 773237 776044 R TrbL/VirB6 plasmid conjugal transfer protein complement(773237..776044) Ehrlichia canis str. Jake 3617952 YP_303166.1 CDS Ecaj_0532 NC_007354.1 776207 778726 R TrbL/VirB6 plasmid conjugal transfer protein complement(776207..778726) Ehrlichia canis str. Jake 3617953 YP_303167.1 CDS Ecaj_0533 NC_007354.1 778764 781166 R type IV secretion system ATPase VirB4 complement(778764..781166) Ehrlichia canis str. Jake 3617954 YP_303168.1 CDS Ecaj_0534 NC_007354.1 781166 781471 R type IV secretion system protein VirB3 complement(781166..781471) Ehrlichia canis str. Jake 3617955 YP_303169.1 CDS Ecaj_0535 NC_007354.1 781835 782452 R superoxide dismutase complement(781835..782452) Ehrlichia canis str. Jake 3617956 YP_303170.1 CDS Ecaj_0536 NC_007354.1 782681 783946 D binding-protein dependent transport system inner membrane protein 782681..783946 Ehrlichia canis str. Jake 3617957 YP_303171.1 CDS Ecaj_0537 NC_007354.1 784752 785651 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(784752..785651) Ehrlichia canis str. Jake 3617959 YP_303172.1 CDS Ecaj_0538 NC_007354.1 785915 787243 R hypothetical protein complement(785915..787243) Ehrlichia canis str. Jake 3617960 YP_303173.1 CDS Ecaj_0539 NC_007354.1 787805 789775 R carbamoyl-phosphate synthase subunit L complement(787805..789775) Ehrlichia canis str. Jake 3617961 YP_303174.1 CDS Ecaj_0540 NC_007354.1 789933 790904 D ribosomal large subunit pseudouridine synthase D 789933..790904 Ehrlichia canis str. Jake 3617962 YP_303175.1 CDS Ecaj_0541 NC_007354.1 791016 792281 D diaminopimelate decarboxylase 791016..792281 Ehrlichia canis str. Jake 3617963 YP_303176.1 CDS rpmB NC_007354.1 793167 793469 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(793167..793469) Ehrlichia canis str. Jake 3617964 YP_303177.1 CDS Ecaj_0544 NC_007354.1 794253 796229 R primosomal protein n complement(794253..796229) Ehrlichia canis str. Jake 3617966 YP_303178.1 CDS Ecaj_0545 NC_007354.1 796732 797706 R hypothetical protein complement(796732..797706) Ehrlichia canis str. Jake 3617967 YP_303179.1 CDS Ecaj_0546 NC_007354.1 797937 798659 D uroporphyrinogen III synthase HEM4 797937..798659 Ehrlichia canis str. Jake 3617968 YP_303180.1 CDS Ecaj_0547 NC_007354.1 799104 800828 R peptidase M24 complement(799104..800828) Ehrlichia canis str. Jake 3617969 YP_303181.1 CDS Ecaj_0548 NC_007354.1 801608 802078 R hypothetical protein complement(801608..802078) Ehrlichia canis str. Jake 3617970 YP_303182.1 CDS Ecaj_0549 NC_007354.1 802212 803039 R hypothetical protein complement(802212..803039) Ehrlichia canis str. Jake 3617933 YP_303183.1 CDS era NC_007354.1 803029 803919 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(803029..803919) Ehrlichia canis str. Jake 3617934 YP_303184.1 CDS Ecaj_0551 NC_007354.1 804407 805756 R signal recognition particle subunit FFH/SRP54 (srp54) complement(804407..805756) Ehrlichia canis str. Jake 3617935 YP_303185.1 CDS Ecaj_0552 NC_007354.1 805741 807336 R subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D complement(805741..807336) Ehrlichia canis str. Jake 3617936 YP_303186.1 CDS Ecaj_0553 NC_007354.1 808194 808658 R hypothetical protein complement(808194..808658) Ehrlichia canis str. Jake 3617937 YP_303187.1 CDS dnaK NC_007354.1 808925 810829 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(808925..810829) Ehrlichia canis str. Jake 3617938 YP_303188.1 CDS Ecaj_0555 NC_007354.1 810931 812757 R ribonuclease E complement(810931..812757) Ehrlichia canis str. Jake 3617939 YP_303189.1 CDS Ecaj_0556 NC_007354.1 812888 813223 R subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C complement(812888..813223) Ehrlichia canis str. Jake 3617940 YP_303190.1 CDS Ecaj_0557 NC_007354.1 813265 813684 R subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B complement(813265..813684) Ehrlichia canis str. Jake 3617941 YP_303191.1 CDS Ecaj_0558 NC_007354.1 813677 814222 R subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B complement(813677..814222) Ehrlichia canis str. Jake 3617942 YP_303192.1 CDS Ecaj_0559 NC_007354.1 814212 814493 R subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit G complement(814212..814493) Ehrlichia canis str. Jake 3617943 YP_303193.1 CDS Ecaj_0560 NC_007354.1 814508 814825 R subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit F complement(814508..814825) Ehrlichia canis str. Jake 3617944 YP_303194.1 CDS Ecaj_0561 NC_007354.1 815260 817245 R transketolase complement(815260..817245) Ehrlichia canis str. Jake 3617945 YP_303195.1 CDS Ecaj_0562 NC_007354.1 817303 818778 R thermostable carboxypeptidase 1 complement(817303..818778) Ehrlichia canis str. Jake 3617946 YP_303196.1 CDS Ecaj_0563 NC_007354.1 819437 819925 D OmpA/MotB domain-containing protein 819437..819925 Ehrlichia canis str. Jake 3617947 YP_303197.1 CDS Ecaj_0564 NC_007354.1 820239 821534 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 820239..821534 Ehrlichia canis str. Jake 3617948 YP_303198.1 CDS Ecaj_0565 NC_007354.1 822647 823117 R hypothetical protein complement(822647..823117) Ehrlichia canis str. Jake 3617949 YP_303199.1 CDS Ecaj_0566 NC_007354.1 823362 825230 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(823362..825230) Ehrlichia canis str. Jake 3617950 YP_303200.1 CDS Ecaj_0567 NC_007354.1 825706 826557 D farnesyl-diphosphate synthase 825706..826557 Ehrlichia canis str. Jake 3617914 YP_303201.1 CDS Ecaj_0568 NC_007354.1 826563 827474 D hypothetical protein 826563..827474 Ehrlichia canis str. Jake 3617915 YP_303202.1 CDS Ecaj_0570 NC_007354.1 828180 829241 R FAD dependent oxidoreductase complement(828180..829241) Ehrlichia canis str. Jake 3617917 YP_303203.1 CDS Ecaj_0571 NC_007354.1 829693 831159 R unwinds double stranded DNA; replicative DNA helicase complement(829693..831159) Ehrlichia canis str. Jake 3617918 YP_303204.1 CDS Ecaj_0572 NC_007354.1 831917 832342 R hypothetical protein complement(831917..832342) Ehrlichia canis str. Jake 3617919 YP_303205.1 CDS Ecaj_0573 NC_007354.1 832486 832905 D cytidine/deoxycytidylate deaminase 832486..832905 Ehrlichia canis str. Jake 3617920 YP_303206.1 CDS Ecaj_0574 NC_007354.1 833811 834770 R 3-oxoacyl-ACP synthase complement(833811..834770) Ehrlichia canis str. Jake 3617921 YP_303207.1 CDS Ecaj_0575 NC_007354.1 834783 835796 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX complement(834783..835796) Ehrlichia canis str. Jake 3617922 YP_303208.1 CDS rpmF NC_007354.1 835824 836009 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(835824..836009) Ehrlichia canis str. Jake 3617923 YP_303209.1 CDS Ecaj_0577 NC_007354.1 836152 837342 D queuine/other tRNA- ribosyl transferase 836152..837342 Ehrlichia canis str. Jake 3617924 YP_303210.1 CDS Ecaj_0578 NC_007354.1 838236 838997 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein complement(838236..838997) Ehrlichia canis str. Jake 3617925 YP_303211.1 CDS Ecaj_0579 NC_007354.1 839011 839814 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(839011..839814) Ehrlichia canis str. Jake 3617926 YP_303212.1 CDS Ecaj_0580 NC_007354.1 839811 840302 R flavin reductase-like protein complement(839811..840302) Ehrlichia canis str. Jake 3617927 YP_303213.1 CDS ubiA NC_007354.1 840351 841229 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase complement(840351..841229) Ehrlichia canis str. Jake 3617928 YP_303214.1 CDS ubiA NC_007354.1 841704 842591 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase complement(841704..842591) Ehrlichia canis str. Jake 3617929 YP_303215.1 CDS rpmH NC_007354.1 842873 843007 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 842873..843007 Ehrlichia canis str. Jake 3617930 YP_303216.1 CDS Ecaj_0584 NC_007354.1 842998 843357 D hypothetical protein 842998..843357 Ehrlichia canis str. Jake 3617931 YP_303217.1 CDS Ecaj_0585 NC_007354.1 843427 844737 D Sodium:alanine symporter 843427..844737 Ehrlichia canis str. Jake 3617932 YP_303218.1 CDS Ecaj_0586 NC_007354.1 845542 847560 R ComEC/Rec2-like protein complement(845542..847560) Ehrlichia canis str. Jake 3618081 YP_303219.1 CDS pheT NC_007354.1 848251 850608 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(848251..850608) Ehrlichia canis str. Jake 3618082 YP_303220.1 CDS rplQ NC_007354.1 850652 851050 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(850652..851050) Ehrlichia canis str. Jake 3618083 YP_303221.1 CDS Ecaj_0589 NC_007354.1 851060 852178 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(851060..852178) Ehrlichia canis str. Jake 3618084 YP_303222.1 CDS Ecaj_0590 NC_007354.1 852208 852588 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(852208..852588) Ehrlichia canis str. Jake 3618085 YP_303223.1 CDS rpsM NC_007354.1 852600 852971 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(852600..852971) Ehrlichia canis str. Jake 3618086 YP_303224.1 CDS Ecaj_0592 NC_007354.1 853030 853695 R adenylate kinase complement(853030..853695) Ehrlichia canis str. Jake 3618087 YP_303225.1 CDS secY NC_007354.1 853680 854990 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(853680..854990) Ehrlichia canis str. Jake 3618088 YP_303226.1 CDS rplO NC_007354.1 855018 855488 R late assembly protein; 50S ribosomal protein L15 complement(855018..855488) Ehrlichia canis str. Jake 3618089 YP_303227.1 CDS rpsE NC_007354.1 855492 856016 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(855492..856016) Ehrlichia canis str. Jake 3618090 YP_303228.1 CDS rplR NC_007354.1 856034 856399 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(856034..856399) Ehrlichia canis str. Jake 3618091 YP_303229.1 CDS rplF NC_007354.1 856417 856953 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(856417..856953) Ehrlichia canis str. Jake 3618092 YP_303230.1 CDS rpsH NC_007354.1 856965 857363 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(856965..857363) Ehrlichia canis str. Jake 3618093 YP_303231.1 CDS rpsN NC_007354.1 857386 857691 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(857386..857691) Ehrlichia canis str. Jake 3618094 YP_303232.1 CDS rplE NC_007354.1 857701 858234 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(857701..858234) Ehrlichia canis str. Jake 3618095 YP_303233.1 CDS rplX NC_007354.1 858245 858574 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(858245..858574) Ehrlichia canis str. Jake 3618096 YP_303234.1 CDS rplN NC_007354.1 858576 858935 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(858576..858935) Ehrlichia canis str. Jake 3618097 YP_303235.1 CDS rpsQ NC_007354.1 858949 859200 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(858949..859200) Ehrlichia canis str. Jake 3618098 YP_303236.1 CDS Ecaj_0604 NC_007354.1 859169 859372 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(859169..859372) Ehrlichia canis str. Jake 3618099 YP_303237.1 CDS rplP NC_007354.1 859385 859795 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(859385..859795) Ehrlichia canis str. Jake 3618063 YP_303238.1 CDS rpsC NC_007354.1 859812 860447 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(859812..860447) Ehrlichia canis str. Jake 3618064 YP_303239.1 CDS rplV NC_007354.1 860451 860795 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(860451..860795) Ehrlichia canis str. Jake 3618065 YP_303240.1 CDS rpsS NC_007354.1 860808 861089 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(860808..861089) Ehrlichia canis str. Jake 3618066 YP_303241.1 CDS rplB NC_007354.1 861093 861923 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(861093..861923) Ehrlichia canis str. Jake 3618067 YP_303242.1 CDS rplW NC_007354.1 861931 862221 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(861931..862221) Ehrlichia canis str. Jake 3618068 YP_303243.1 CDS rplD NC_007354.1 862218 862835 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(862218..862835) Ehrlichia canis str. Jake 3618069 YP_303244.1 CDS rplC NC_007354.1 862843 863538 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(862843..863538) Ehrlichia canis str. Jake 3618070 YP_303245.1 CDS rpsJ NC_007354.1 863531 863857 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(863531..863857) Ehrlichia canis str. Jake 3618071 YP_303246.1 CDS Ecaj_0614 NC_007354.1 863865 865052 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(863865..865052) Ehrlichia canis str. Jake 3618072 YP_303247.1 CDS Ecaj_0615 NC_007354.1 865410 866168 D RNA methyl transferase TrmH 865410..866168 Ehrlichia canis str. Jake 3618075 YP_303248.1 CDS Ecaj_0616 NC_007354.1 866149 866793 D cytidylate kinase 866149..866793 Ehrlichia canis str. Jake 3618076 YP_303249.1 CDS rpsA NC_007354.1 866858 868561 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 866858..868561 Ehrlichia canis str. Jake 3618077 YP_303250.1 CDS Ecaj_0618 NC_007354.1 868575 869441 D signal peptide peptidase SppA 868575..869441 Ehrlichia canis str. Jake 3618078 YP_303251.1 CDS Ecaj_0619 NC_007354.1 869447 869710 D histone-like DNA-binding protein 869447..869710 Ehrlichia canis str. Jake 3618079 YP_303252.1 CDS Ecaj_0620 NC_007354.1 869747 870040 D hypothetical protein 869747..870040 Ehrlichia canis str. Jake 3618080 YP_303253.1 CDS Ecaj_0621 NC_007354.1 870033 870401 D hypothetical protein 870033..870401 Ehrlichia canis str. Jake 3618164 YP_303254.1 CDS Ecaj_0622 NC_007354.1 870551 871468 D hypothetical protein 870551..871468 Ehrlichia canis str. Jake 3618165 YP_303255.1 CDS hemH NC_007354.1 871552 872565 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 871552..872565 Ehrlichia canis str. Jake 3618166 YP_303256.1 CDS Ecaj_0624 NC_007354.1 873061 874116 R AFG1-like ATPase complement(873061..874116) Ehrlichia canis str. Jake 3618167 YP_303257.1 CDS Ecaj_0625 NC_007354.1 874502 874840 R hypothetical protein complement(874502..874840) Ehrlichia canis str. Jake 3618168 YP_303258.1 CDS Ecaj_0626 NC_007354.1 875323 876180 R Band 7 protein complement(875323..876180) Ehrlichia canis str. Jake 3618169 YP_303259.1 CDS Ecaj_0627 NC_007354.1 876828 877283 R ankyrin complement(876828..877283) Ehrlichia canis str. Jake 3618170 YP_303260.1 CDS Ecaj_0628 NC_007354.1 877280 877636 R hypothetical protein complement(877280..877636) Ehrlichia canis str. Jake 3618171 YP_303261.1 CDS Ecaj_0629 NC_007354.1 877773 880337 D UvrD/REP helicase 877773..880337 Ehrlichia canis str. Jake 3618172 YP_303262.1 CDS Ecaj_0630 NC_007354.1 881119 882093 R zinc-containing alcohol dehydrogenase superfamily protein complement(881119..882093) Ehrlichia canis str. Jake 3618173 YP_303263.1 CDS Ecaj_0631 NC_007354.1 882973 884751 R Type I secretion system ATPase, PrtD complement(882973..884751) Ehrlichia canis str. Jake 3618174 YP_303264.1 CDS Ecaj_0632 NC_007354.1 884873 885100 D hypothetical protein 884873..885100 Ehrlichia canis str. Jake 3618175 YP_303265.1 CDS Ecaj_0633 NC_007354.1 885113 885955 D dihydropteroate synthase 885113..885955 Ehrlichia canis str. Jake 3618176 YP_303266.1 CDS Ecaj_0634 NC_007354.1 887142 888221 R hypothetical protein complement(887142..888221) Ehrlichia canis str. Jake 3618177 YP_303267.1 CDS carB NC_007354.1 889021 892251 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 889021..892251 Ehrlichia canis str. Jake 3618178 YP_303268.1 CDS Ecaj_0636 NC_007354.1 892718 893014 R hypothetical protein complement(892718..893014) Ehrlichia canis str. Jake 3618179 YP_303269.1 CDS fumC NC_007354.1 893114 894499 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(893114..894499) Ehrlichia canis str. Jake 3618180 YP_303270.1 CDS Ecaj_0638 NC_007354.1 894775 895419 D DNA/pantothenate metabolism flavoprotein-domain-containin protein 894775..895419 Ehrlichia canis str. Jake 3618181 YP_303271.1 CDS Ecaj_0639 NC_007354.1 895753 897096 D dihydroorotase 895753..897096 Ehrlichia canis str. Jake 3618182 YP_303272.1 CDS lipB NC_007354.1 897847 898491 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(897847..898491) Ehrlichia canis str. Jake 3617971 YP_303273.1 CDS Ecaj_0641 NC_007354.1 899693 900319 R phosphoribosylglycinamide formyltransferase complement(899693..900319) Ehrlichia canis str. Jake 3617972 YP_303274.1 CDS Ecaj_0642 NC_007354.1 900459 901961 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(900459..901961) Ehrlichia canis str. Jake 3617973 YP_303275.1 CDS Ecaj_0643 NC_007354.1 902391 903065 D intradiol ring-cleavage dioxygenase 902391..903065 Ehrlichia canis str. Jake 3617974 YP_303276.1 CDS Ecaj_0644 NC_007354.1 903854 904096 D hypothetical protein 903854..904096 Ehrlichia canis str. Jake 3617975 YP_303277.1 CDS Ecaj_0645 NC_007354.1 904238 906811 R ATPase AAA complement(904238..906811) Ehrlichia canis str. Jake 3617976 YP_303278.1 CDS Ecaj_0646 NC_007354.1 907150 907875 D short-chain dehydrogenase 907150..907875 Ehrlichia canis str. Jake 3617977 YP_303279.1 CDS groEL NC_007354.1 908789 910447 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(908789..910447) Ehrlichia canis str. Jake 3617978 YP_303280.1 CDS groES NC_007354.1 910541 910825 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(910541..910825) Ehrlichia canis str. Jake 3617979 YP_303281.1 CDS Ecaj_0649 NC_007354.1 911086 911778 D DNA repair protein RadC 911086..911778 Ehrlichia canis str. Jake 3617980 YP_303282.1 CDS Ecaj_0652 NC_007354.1 913105 913899 R phosphoribosylformylglycinamidine synthase I complement(913105..913899) Ehrlichia canis str. Jake 3617983 YP_303283.1 CDS Ecaj_0653 NC_007354.1 914728 916605 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 914728..916605 Ehrlichia canis str. Jake 3617984 YP_303284.1 CDS glpX NC_007354.1 917067 917996 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(917067..917996) Ehrlichia canis str. Jake 3617985 YP_303285.1 CDS Ecaj_0655 NC_007354.1 918315 918920 D peptidase M23B 918315..918920 Ehrlichia canis str. Jake 3618141 YP_303286.1 CDS Ecaj_0656 NC_007354.1 919318 919773 D hypothetical protein 919318..919773 Ehrlichia canis str. Jake 3618142 YP_303287.1 CDS Ecaj_0657 NC_007354.1 920133 921107 D biotin synthase 920133..921107 Ehrlichia canis str. Jake 3618143 YP_303288.1 CDS Ecaj_0658 NC_007354.1 923693 926707 D phosphoribosylformylglycinamidine synthase 923693..926707 Ehrlichia canis str. Jake 3617873 YP_303289.1 CDS Ecaj_0659 NC_007354.1 928689 929207 D 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 928689..929207 Ehrlichia canis str. Jake 3617874 YP_303290.1 CDS Ecaj_0660 NC_007354.1 929708 930301 R hypothetical protein complement(929708..930301) Ehrlichia canis str. Jake 3617875 YP_303291.1 CDS Ecaj_0661 NC_007354.1 930387 931694 R peptidase M48, Ste24p complement(930387..931694) Ehrlichia canis str. Jake 3617876 YP_303292.1 CDS Ecaj_0662 NC_007354.1 931904 932260 D Iojap-related protein 931904..932260 Ehrlichia canis str. Jake 3617877 YP_303293.1 CDS Ecaj_0663 NC_007354.1 932689 933570 D hypothetical protein 932689..933570 Ehrlichia canis str. Jake 3617878 YP_303294.1 CDS Ecaj_0664 NC_007354.1 933692 934324 R hypothetical protein complement(933692..934324) Ehrlichia canis str. Jake 3617879 YP_303295.1 CDS Ecaj_0665 NC_007354.1 934473 935501 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 934473..935501 Ehrlichia canis str. Jake 3617880 YP_303296.1 CDS Ecaj_0666 NC_007354.1 937211 938143 R Phage integrase, N-terminal SAM- like complement(937211..938143) Ehrlichia canis str. Jake 3617881 YP_303297.1 CDS Ecaj_0667 NC_007354.1 938350 939324 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 938350..939324 Ehrlichia canis str. Jake 3617882 YP_303298.1 CDS Ecaj_0668 NC_007354.1 940729 942144 R nitrogen assimilation regulatory protein ntrX complement(940729..942144) Ehrlichia canis str. Jake 3617883 YP_303299.1 CDS Ecaj_0669 NC_007354.1 942420 943247 R cell division protein FtsQ complement(942420..943247) Ehrlichia canis str. Jake 3617884 YP_303300.1 CDS Ecaj_0670 NC_007354.1 944412 945353 R catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase complement(944412..945353) Ehrlichia canis str. Jake 3617885 YP_303301.1 CDS Ecaj_0671 NC_007354.1 945670 946221 R transport-associated domain-containing protein complement(945670..946221) Ehrlichia canis str. Jake 3617886 YP_303302.1 CDS aspS NC_007354.1 946659 948431 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 946659..948431 Ehrlichia canis str. Jake 3617887 YP_303303.1 CDS Ecaj_0673 NC_007354.1 948894 949529 D HAD family hydrolase 948894..949529 Ehrlichia canis str. Jake 3617888 YP_303304.1 CDS Ecaj_0674 NC_007354.1 949526 950017 D hypothetical protein 949526..950017 Ehrlichia canis str. Jake 3617889 YP_303305.1 CDS Ecaj_0675 NC_007354.1 950364 952988 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 950364..952988 Ehrlichia canis str. Jake 3617890 YP_303306.1 CDS Ecaj_0676 NC_007354.1 953454 954143 D hypothetical protein 953454..954143 Ehrlichia canis str. Jake 3617891 YP_303307.1 CDS Ecaj_0677 NC_007354.1 954321 955811 D NADH dehydrogenase (quinone) 954321..955811 Ehrlichia canis str. Jake 3618256 YP_303308.1 CDS Ecaj_0678 NC_007354.1 956080 956601 D cytochrome c, class I 956080..956601 Ehrlichia canis str. Jake 3618257 YP_303309.1 CDS Ecaj_0679 NC_007354.1 957053 957826 D Alpha/beta hydrolase 957053..957826 Ehrlichia canis str. Jake 3618258 YP_303310.1 CDS Ecaj_0680 NC_007354.1 958811 959713 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(958811..959713) Ehrlichia canis str. Jake 3618260 YP_303311.1 CDS Ecaj_0681 NC_007354.1 960032 960661 R guanylate kinase complement(960032..960661) Ehrlichia canis str. Jake 3618261 YP_303312.1 CDS Ecaj_0682 NC_007354.1 961074 961778 D cytochrome c-type biogenesis protein CcmC 961074..961778 Ehrlichia canis str. Jake 3618262 YP_303313.1 CDS ruvA NC_007354.1 961787 962359 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 961787..962359 Ehrlichia canis str. Jake 3618263 YP_303314.1 CDS ruvB NC_007354.1 963546 964535 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 963546..964535 Ehrlichia canis str. Jake 3618264 YP_303315.1 CDS Ecaj_0685 NC_007354.1 965902 967062 R Bcr/CflA subfamily drug resistance transporter complement(965902..967062) Ehrlichia canis str. Jake 3618265 YP_303316.1 CDS thyX NC_007354.1 967436 968317 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(967436..968317) Ehrlichia canis str. Jake 3618266 YP_303317.1 CDS sdhB NC_007354.1 969251 970027 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(969251..970027) Ehrlichia canis str. Jake 3618267 YP_303318.1 CDS sdhA NC_007354.1 970064 971860 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(970064..971860) Ehrlichia canis str. Jake 3618268 YP_303319.1 CDS Ecaj_0689 NC_007354.1 972437 972700 R hypothetical protein complement(972437..972700) Ehrlichia canis str. Jake 3618269 YP_303320.1 CDS Ecaj_0690 NC_007354.1 972949 974694 R ABC transporter transmembrane protein complement(972949..974694) Ehrlichia canis str. Jake 3618270 YP_303321.1 CDS Ecaj_0691 NC_007354.1 974697 975026 R CyaY protein complement(974697..975026) Ehrlichia canis str. Jake 3618271 YP_303322.1 CDS glyA NC_007354.1 975205 976470 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(975205..976470) Ehrlichia canis str. Jake 3618272 YP_303323.1 CDS rplI NC_007354.1 976545 977171 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(976545..977171) Ehrlichia canis str. Jake 3618273 YP_303324.1 CDS rpsR NC_007354.1 977192 977479 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(977192..977479) Ehrlichia canis str. Jake 3618274 YP_303325.1 CDS rpsF NC_007354.1 977493 977822 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(977493..977822) Ehrlichia canis str. Jake 3618506 YP_303326.1 CDS Ecaj_0696 NC_007354.1 977960 978562 R colicin V production protein complement(977960..978562) Ehrlichia canis str. Jake 3617896 YP_303327.1 CDS Ecaj_0697 NC_007354.1 978568 981219 R TRAP dicarboxylate transporter subunit DctM complement(978568..981219) Ehrlichia canis str. Jake 3617897 YP_303328.1 CDS Ecaj_0698 NC_007354.1 981708 983060 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 981708..983060 Ehrlichia canis str. Jake 3617898 YP_303329.1 CDS Ecaj_0699 NC_007354.1 983057 983554 D hypothetical protein 983057..983554 Ehrlichia canis str. Jake 3617899 YP_303330.1 CDS Ecaj_0700 NC_007354.1 984031 984261 D BolA-like protein 984031..984261 Ehrlichia canis str. Jake 3617900 YP_303331.1 CDS Ecaj_0701 NC_007354.1 984268 984600 D glutaredoxin-like protein 984268..984600 Ehrlichia canis str. Jake 3617901 YP_303332.1 CDS Ecaj_0702 NC_007354.1 984628 986661 D NAD-dependent DNA ligase 984628..986661 Ehrlichia canis str. Jake 3617902 YP_303333.1 CDS Ecaj_0703 NC_007354.1 987899 989059 R 3'-5' exonuclease complement(987899..989059) Ehrlichia canis str. Jake 3617903 YP_303334.1 CDS Ecaj_0704 NC_007354.1 989228 991369 R sensor histidine kinase complement(989228..991369) Ehrlichia canis str. Jake 3617904 YP_303335.1 CDS Ecaj_0705 NC_007354.1 991540 991803 R cold-shock DNA-binding protein family protein complement(991540..991803) Ehrlichia canis str. Jake 3617905 YP_303336.1 CDS Ecaj_0706 NC_007354.1 992226 993047 D hypothetical protein 992226..993047 Ehrlichia canis str. Jake 3617906 YP_303337.1 CDS dcd NC_007354.1 993349 993912 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 993349..993912 Ehrlichia canis str. Jake 3617907 YP_303338.1 CDS Ecaj_0708 NC_007354.1 994144 994776 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 994144..994776 Ehrlichia canis str. Jake 3617908 YP_303339.1 CDS Ecaj_0709 NC_007354.1 995307 996350 R cytochrome oxidase assembly complement(995307..996350) Ehrlichia canis str. Jake 3617909 YP_303340.1 CDS Ecaj_0710 NC_007354.1 996800 997540 D DSBA oxidoreductase 996800..997540 Ehrlichia canis str. Jake 3617910 YP_303341.1 CDS Ecaj_0711 NC_007354.1 997580 1000903 R hypothetical protein complement(997580..1000903) Ehrlichia canis str. Jake 3617911 YP_303342.1 CDS hisS NC_007354.1 1001167 1002408 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1001167..1002408) Ehrlichia canis str. Jake 3617912 YP_303343.1 CDS Ecaj_0713 NC_007354.1 1002560 1003336 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1002560..1003336 Ehrlichia canis str. Jake 3617913 YP_303344.1 CDS Ecaj_0714 NC_007354.1 1003557 1005113 R hypothetical protein complement(1003557..1005113) Ehrlichia canis str. Jake 3618107 YP_303345.1 CDS Ecaj_0715 NC_007354.1 1005217 1010973 R hypothetical protein complement(1005217..1010973) Ehrlichia canis str. Jake 3618108 YP_303346.1 CDS Ecaj_0716 NC_007354.1 1011247 1016052 R hypothetical protein complement(1011247..1016052) Ehrlichia canis str. Jake 3618109 YP_303347.1 CDS Ecaj_0717 NC_007354.1 1016625 1017305 R hypothetical protein complement(1016625..1017305) Ehrlichia canis str. Jake 3618110 YP_303348.1 CDS Ecaj_0718 NC_007354.1 1018260 1019030 R hypothetical protein complement(1018260..1019030) Ehrlichia canis str. Jake 3618111 YP_303349.1 CDS Ecaj_0719 NC_007354.1 1020092 1020718 R hypothetical protein complement(1020092..1020718) Ehrlichia canis str. Jake 3618112 YP_303350.1 CDS Ecaj_0720 NC_007354.1 1021455 1022120 R hypothetical protein complement(1021455..1022120) Ehrlichia canis str. Jake 3618113 YP_303351.1 CDS Ecaj_0721 NC_007354.1 1023542 1024213 R hypothetical protein complement(1023542..1024213) Ehrlichia canis str. Jake 3618114 YP_303352.1 CDS Ecaj_0722 NC_007354.1 1025370 1025582 R hypothetical protein complement(1025370..1025582) Ehrlichia canis str. Jake 3618115 YP_303353.1 CDS Ecaj_0723 NC_007354.1 1026243 1026989 R hypothetical protein complement(1026243..1026989) Ehrlichia canis str. Jake 3618116 YP_303354.1 CDS Ecaj_0724 NC_007354.1 1027259 1027669 R hypothetical protein complement(1027259..1027669) Ehrlichia canis str. Jake 3618117 YP_303355.1 CDS Ecaj_0725 NC_007354.1 1028355 1028927 R hypothetical protein complement(1028355..1028927) Ehrlichia canis str. Jake 3618118 YP_303356.1 CDS Ecaj_0726 NC_007354.1 1029271 1029915 R hypothetical protein complement(1029271..1029915) Ehrlichia canis str. Jake 3618119 YP_303357.1 CDS Ecaj_0727 NC_007354.1 1031113 1031406 R hypothetical protein complement(1031113..1031406) Ehrlichia canis str. Jake 3618120 YP_303358.1 CDS Ecaj_0728 NC_007354.1 1031981 1032667 R hypothetical protein complement(1031981..1032667) Ehrlichia canis str. Jake 3618121 YP_303359.1 CDS Ecaj_0729 NC_007354.1 1033232 1033540 R hypothetical protein complement(1033232..1033540) Ehrlichia canis str. Jake 3618122 YP_303360.1 CDS Ecaj_0730 NC_007354.1 1034526 1035023 R hypothetical protein complement(1034526..1035023) Ehrlichia canis str. Jake 3618123 YP_303361.1 CDS Ecaj_0731 NC_007354.1 1035307 1035969 R hypothetical protein complement(1035307..1035969) Ehrlichia canis str. Jake 3618124 YP_303362.1 CDS Ecaj_0732 NC_007354.1 1036128 1036469 R hypothetical protein complement(1036128..1036469) Ehrlichia canis str. Jake 3618125 YP_303363.1 CDS Ecaj_0733 NC_007354.1 1037138 1037617 R hypothetical protein complement(1037138..1037617) Ehrlichia canis str. Jake 3618126 YP_303364.1 CDS Ecaj_0734 NC_007354.1 1038293 1038691 R hypothetical protein complement(1038293..1038691) Ehrlichia canis str. Jake 3617835 YP_303365.1 CDS Ecaj_0735 NC_007354.1 1038799 1039101 R hypothetical protein complement(1038799..1039101) Ehrlichia canis str. Jake 3617836 YP_303366.1 CDS Ecaj_0736 NC_007354.1 1040060 1040626 R hypothetical protein complement(1040060..1040626) Ehrlichia canis str. Jake 3617837 YP_303367.1 CDS Ecaj_0737 NC_007354.1 1040807 1041355 R hypothetical protein complement(1040807..1041355) Ehrlichia canis str. Jake 3617838 YP_303368.1 CDS Ecaj_0738 NC_007354.1 1041910 1042335 R hypothetical protein complement(1041910..1042335) Ehrlichia canis str. Jake 3617839 YP_303369.1 CDS Ecaj_0739 NC_007354.1 1042578 1043240 R hypothetical protein complement(1042578..1043240) Ehrlichia canis str. Jake 3617840 YP_303370.1 CDS Ecaj_0740 NC_007354.1 1043770 1044354 R hypothetical protein complement(1043770..1044354) Ehrlichia canis str. Jake 3617841 YP_303371.1 CDS Ecaj_0741 NC_007354.1 1044567 1044911 R hypothetical protein complement(1044567..1044911) Ehrlichia canis str. Jake 3617842 YP_303372.1 CDS Ecaj_0742 NC_007354.1 1044915 1045121 R hypothetical protein complement(1044915..1045121) Ehrlichia canis str. Jake 3617843 YP_303373.1 CDS Ecaj_0743 NC_007354.1 1046186 1046440 R hypothetical protein complement(1046186..1046440) Ehrlichia canis str. Jake 3617844 YP_303374.1 CDS Ecaj_0744 NC_007354.1 1046428 1046811 R hypothetical protein complement(1046428..1046811) Ehrlichia canis str. Jake 3617845 YP_303375.1 CDS Ecaj_0745 NC_007354.1 1046820 1047116 R hypothetical protein complement(1046820..1047116) Ehrlichia canis str. Jake 3617846 YP_303376.1 CDS Ecaj_0746 NC_007354.1 1047524 1048255 R hypothetical protein complement(1047524..1048255) Ehrlichia canis str. Jake 3617847 YP_303377.1 CDS Ecaj_0747 NC_007354.1 1048381 1048803 R hypothetical protein complement(1048381..1048803) Ehrlichia canis str. Jake 3617848 YP_303378.1 CDS Ecaj_0748 NC_007354.1 1049653 1050018 R hypothetical protein complement(1049653..1050018) Ehrlichia canis str. Jake 3617849 YP_303379.1 CDS Ecaj_0749 NC_007354.1 1050805 1051236 R hypothetical protein complement(1050805..1051236) Ehrlichia canis str. Jake 3617850 YP_303380.1 CDS Ecaj_0750 NC_007354.1 1051316 1051885 D responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 1051316..1051885 Ehrlichia canis str. Jake 3617851 YP_303381.1 CDS Ecaj_0751 NC_007354.1 1052373 1053101 R hypothetical protein complement(1052373..1053101) Ehrlichia canis str. Jake 3617852 YP_303382.1 CDS Ecaj_0752 NC_007354.1 1053607 1054428 R hypothetical protein complement(1053607..1054428) Ehrlichia canis str. Jake 3617853 YP_303383.1 CDS Ecaj_0753 NC_007354.1 1054930 1055745 R hypothetical protein complement(1054930..1055745) Ehrlichia canis str. Jake 3618313 YP_303384.1 CDS Ecaj_0754 NC_007354.1 1056313 1057122 R hypothetical protein complement(1056313..1057122) Ehrlichia canis str. Jake 3618314 YP_303385.1 CDS Ecaj_0755 NC_007354.1 1058048 1058776 R hypothetical protein complement(1058048..1058776) Ehrlichia canis str. Jake 3618315 YP_303386.1 CDS Ecaj_0756 NC_007354.1 1059319 1060317 R hypothetical protein complement(1059319..1060317) Ehrlichia canis str. Jake 3618316 YP_303387.1 CDS Ecaj_0757 NC_007354.1 1060776 1061426 R phosphatidate cytidylyltransferase complement(1060776..1061426) Ehrlichia canis str. Jake 3618317 YP_303388.1 CDS frr NC_007354.1 1062073 1062630 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1062073..1062630) Ehrlichia canis str. Jake 3618318 YP_303389.1 CDS pyrH NC_007354.1 1062654 1063388 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1062654..1063388) Ehrlichia canis str. Jake 3618319 YP_303390.1 CDS Ecaj_0760 NC_007354.1 1063939 1066929 R hypothetical protein complement(1063939..1066929) Ehrlichia canis str. Jake 3618320 YP_303391.1 CDS rnhA NC_007354.1 1067042 1067482 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(1067042..1067482) Ehrlichia canis str. Jake 3618321 YP_303392.1 CDS Ecaj_0762 NC_007354.1 1069271 1070332 D hypothetical protein 1069271..1070332 Ehrlichia canis str. Jake 3618322 YP_303393.1 CDS Ecaj_0764 NC_007354.1 1071250 1071825 D hypothetical protein 1071250..1071825 Ehrlichia canis str. Jake 3618323 YP_303394.1 CDS Ecaj_0765 NC_007354.1 1073495 1076881 D transcription-repair coupling factor 1073495..1076881 Ehrlichia canis str. Jake 3618324 YP_303395.1 CDS Ecaj_0766 NC_007354.1 1078071 1078265 R hypothetical protein complement(1078071..1078265) Ehrlichia canis str. Jake 3618325 YP_303396.1 CDS Ecaj_0767 NC_007354.1 1078533 1078808 R hypothetical protein complement(1078533..1078808) Ehrlichia canis str. Jake 3618326 YP_303397.1 CDS Ecaj_0768 NC_007354.1 1079302 1079439 R hypothetical protein complement(1079302..1079439) Ehrlichia canis str. Jake 3618327 YP_303398.1 CDS Ecaj_0769 NC_007354.1 1079441 1079632 R hypothetical protein complement(1079441..1079632) Ehrlichia canis str. Jake 3618328 YP_303399.1 CDS Ecaj_0770 NC_007354.1 1079865 1080185 R hypothetical protein complement(1079865..1080185) Ehrlichia canis str. Jake 3618329 YP_303400.1 CDS Ecaj_0771 NC_007354.1 1080954 1081691 R hypothetical protein complement(1080954..1081691) Ehrlichia canis str. Jake 3618330 YP_303401.1 CDS Ecaj_0772 NC_007354.1 1082377 1082868 R hypothetical protein complement(1082377..1082868) Ehrlichia canis str. Jake 3618331 YP_303402.2 CDS Ecaj_0773 NC_007354.1 1083100 1083708 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1083100..1083708 Ehrlichia canis str. Jake 3618332 YP_303403.1 CDS Ecaj_0774 NC_007354.1 1083844 1085247 R hypothetical protein complement(1083844..1085247) Ehrlichia canis str. Jake 3617705 YP_303404.1 CDS Ecaj_0775 NC_007354.1 1085763 1087028 D insulinase-like:peptidase M16, C-terminal 1085763..1087028 Ehrlichia canis str. Jake 3617706 YP_303405.1 CDS Ecaj_0776 NC_007354.1 1087456 1088175 R hypothetical protein complement(1087456..1088175) Ehrlichia canis str. Jake 3617707 YP_303406.1 CDS Ecaj_0777 NC_007354.1 1088262 1088795 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(1088262..1088795) Ehrlichia canis str. Jake 3617708 YP_303407.1 CDS Ecaj_0778 NC_007354.1 1088910 1089548 D membrane translocase subunit Tim44 1088910..1089548 Ehrlichia canis str. Jake 3617709 YP_303408.1 CDS Ecaj_0779 NC_007354.1 1090576 1091811 R permease, putative complement(1090576..1091811) Ehrlichia canis str. Jake 3617710 YP_303409.1 CDS Ecaj_0780 NC_007354.1 1091879 1092487 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1091879..1092487) Ehrlichia canis str. Jake 3617711 YP_303410.1 CDS Ecaj_0781 NC_007354.1 1092749 1093729 R malonyl CoA-acyl carrier protein transacylase complement(1092749..1093729) Ehrlichia canis str. Jake 3617712 YP_303411.2 CDS rpmE NC_007354.1 1093901 1094128 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1093901..1094128 Ehrlichia canis str. Jake 3617713 YP_303412.1 CDS ppnK NC_007354.1 1094166 1094957 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1094166..1094957 Ehrlichia canis str. Jake 3617714 YP_303413.1 CDS Ecaj_0784 NC_007354.1 1095154 1096611 D inosine-5'-monophosphate dehydrogenase 1095154..1096611 Ehrlichia canis str. Jake 3617715 YP_303414.1 CDS Ecaj_0785 NC_007354.1 1102054 1102905 D Alpha/beta hydrolase 1102054..1102905 Ehrlichia canis str. Jake 3617718 YP_303415.1 CDS Ecaj_0786 NC_007354.1 1103119 1104102 D pyruvate dehydrogenase (lipoamide) 1103119..1104102 Ehrlichia canis str. Jake 3617719 YP_303416.1 CDS Ecaj_0787 NC_007354.1 1104922 1105734 D conjugal transfer protein TrbG/VirB9/CagX 1104922..1105734 Ehrlichia canis str. Jake 3617720 YP_303417.1 CDS Ecaj_0788 NC_007354.1 1106543 1106875 D thioredoxin 1106543..1106875 Ehrlichia canis str. Jake 3617721 YP_303418.1 CDS Ecaj_0789 NC_007354.1 1108752 1109987 R tRNA 2-methylthioadenosine synthase complement(1108752..1109987) Ehrlichia canis str. Jake 3617578 YP_303419.1 CDS Ecaj_0790 NC_007354.1 1110510 1110698 R exodeoxyribonuclease VII small subunit complement(1110510..1110698) Ehrlichia canis str. Jake 3617579 YP_303420.1 CDS Ecaj_0791 NC_007354.1 1110765 1111058 D ETC complex I subunit region 1110765..1111058 Ehrlichia canis str. Jake 3617580 YP_303421.1 CDS Ecaj_0792 NC_007354.1 1111914 1112831 D auxin efflux carrier 1111914..1112831 Ehrlichia canis str. Jake 3617581 YP_303422.1 CDS Ecaj_0793 NC_007354.1 1113378 1113926 R hypothetical protein complement(1113378..1113926) Ehrlichia canis str. Jake 3617582 YP_303423.1 CDS Ecaj_0794 NC_007354.1 1113932 1115131 R hypothetical protein complement(1113932..1115131) Ehrlichia canis str. Jake 3617583 YP_303424.1 CDS gltX NC_007354.1 1116686 1118017 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(1116686..1118017) Ehrlichia canis str. Jake 3617585 YP_303425.1 CDS Ecaj_0796 NC_007354.1 1118334 1118696 D hypothetical protein 1118334..1118696 Ehrlichia canis str. Jake 3617586 YP_303426.1 CDS thiG NC_007354.1 1119526 1120311 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(1119526..1120311) Ehrlichia canis str. Jake 3617587 YP_303427.1 CDS Ecaj_0798 NC_007354.1 1120431 1120607 R putative ThiS sulfur transfer protein complement(1120431..1120607) Ehrlichia canis str. Jake 3617588 YP_303428.1 CDS Ecaj_0799 NC_007354.1 1120888 1122312 D hypothetical protein 1120888..1122312 Ehrlichia canis str. Jake 3617589 YP_303429.1 CDS Ecaj_0800 NC_007354.1 1123265 1123825 R nitrogen-fixing NifU, C-terminal complement(1123265..1123825) Ehrlichia canis str. Jake 3617590 YP_303430.1 CDS Ecaj_0801 NC_007354.1 1123836 1124258 D heat shock protein DnaJ, N-terminal 1123836..1124258 Ehrlichia canis str. Jake 3617591 YP_303431.1 CDS Ecaj_0802 NC_007354.1 1124455 1124760 D hypothetical protein 1124455..1124760 Ehrlichia canis str. Jake 3617592 YP_303432.1 CDS rho NC_007354.1 1125867 1127276 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(1125867..1127276) Ehrlichia canis str. Jake 3617593 YP_303433.1 CDS Ecaj_0804 NC_007354.1 1128152 1128721 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1128152..1128721 Ehrlichia canis str. Jake 3617594 YP_303434.1 CDS hslU NC_007354.1 1128723 1130201 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1128723..1130201 Ehrlichia canis str. Jake 3617595 YP_303435.1 CDS Ecaj_0806 NC_007354.1 1130204 1130899 D 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase / demethylmenaquinone methyltransferase 1130204..1130899 Ehrlichia canis str. Jake 3617596 YP_303436.1 CDS Ecaj_0807 NC_007354.1 1132760 1134280 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1132760..1134280) Ehrlichia canis str. Jake 3617805 YP_303437.1 CDS Ecaj_0808 NC_007354.1 1134906 1136159 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1134906..1136159 Ehrlichia canis str. Jake 3617806 YP_303438.1 CDS Ecaj_0809 NC_007354.1 1136718 1137461 D cytochrome-c oxidase 1136718..1137461 Ehrlichia canis str. Jake 3617807 YP_303439.1 CDS Ecaj_0810 NC_007354.1 1137470 1139026 D cytochrome-c oxidase 1137470..1139026 Ehrlichia canis str. Jake 3617808 YP_303440.1 CDS Ecaj_0811 NC_007354.1 1139029 1139916 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 1139029..1139916 Ehrlichia canis str. Jake 3617809 YP_303441.1 CDS Ecaj_0812 NC_007354.1 1141023 1141787 R hypothetical protein complement(1141023..1141787) Ehrlichia canis str. Jake 3617810 YP_303442.1 CDS Ecaj_0813 NC_007354.1 1141970 1143235 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1141970..1143235 Ehrlichia canis str. Jake 3617811 YP_303443.1 CDS Ecaj_0814 NC_007354.1 1144299 1144745 D protein translocase subunit yajC 1144299..1144745 Ehrlichia canis str. Jake 3617812 YP_303444.1 CDS Ecaj_0815 NC_007354.1 1144847 1145974 R DNA polymerase III subunit beta complement(1144847..1145974) Ehrlichia canis str. Jake 3617813 YP_303445.1 CDS Ecaj_0816 NC_007354.1 1146059 1146709 R 3'-5' exonuclease complement(1146059..1146709) Ehrlichia canis str. Jake 3617814 YP_303446.1 CDS Ecaj_0817 NC_007354.1 1146762 1147562 R response regulator receiver: C terminal complement(1146762..1147562) Ehrlichia canis str. Jake 3617815 YP_303447.1 CDS Ecaj_0818 NC_007354.1 1147944 1148579 R transcriptional regulator complement(1147944..1148579) Ehrlichia canis str. Jake 3617816 YP_303448.1 CDS Ecaj_0819 NC_007354.1 1149137 1149655 R inorganic diphosphatase complement(1149137..1149655) Ehrlichia canis str. Jake 3617817 YP_303449.1 CDS argC NC_007354.1 1150891 1151931 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(1150891..1151931) Ehrlichia canis str. Jake 3617818 YP_303450.1 CDS rpsI NC_007354.1 1151940 1152389 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(1151940..1152389) Ehrlichia canis str. Jake 3617819 YP_303451.1 CDS rplM NC_007354.1 1152389 1152859 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(1152389..1152859) Ehrlichia canis str. Jake 3617820 YP_303452.1 CDS Ecaj_0823 NC_007354.1 1153336 1154634 D Outer membrane efflux protein 1153336..1154634 Ehrlichia canis str. Jake 3617821 YP_303453.1 CDS Ecaj_0824 NC_007354.1 1154646 1155374 D hypothetical protein 1154646..1155374 Ehrlichia canis str. Jake 3617822 YP_303454.1 CDS Ecaj_0825 NC_007354.1 1156481 1157536 R hypothetical protein complement(1156481..1157536) Ehrlichia canis str. Jake 3617823 YP_303455.1 CDS Ecaj_0826 NC_007354.1 1157655 1158611 D ribose-phosphate pyrophosphokinase 1157655..1158611 Ehrlichia canis str. Jake 3617747 YP_303456.1 CDS Ecaj_0827 NC_007354.1 1158626 1158970 D aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C 1158626..1158970 Ehrlichia canis str. Jake 3617748 YP_303457.1 CDS Ecaj_0828 NC_007354.1 1159896 1162547 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1159896..1162547) Ehrlichia canis str. Jake 3617749 YP_303458.1 CDS apaG NC_007354.1 1163034 1163438 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(1163034..1163438) Ehrlichia canis str. Jake 3617750 YP_303459.1 CDS Ecaj_0830 NC_007354.1 1163734 1164825 D phosphoribosylaminoimidazole carboxylase 1163734..1164825 Ehrlichia canis str. Jake 3617751 YP_303460.1 CDS Ecaj_0831 NC_007354.1 1165161 1166003 D surface antigen msp4 1165161..1166003 Ehrlichia canis str. Jake 3617752 YP_303461.1 CDS Ecaj_0832 NC_007354.1 1166331 1167161 D surface antigen msp4 1166331..1167161 Ehrlichia canis str. Jake 3617753 YP_303462.1 CDS Ecaj_0833 NC_007354.1 1167372 1168235 D surface antigen msp4 1167372..1168235 Ehrlichia canis str. Jake 3617754 YP_303463.1 CDS Ecaj_0834 NC_007354.1 1168714 1171062 R hypothetical protein complement(1168714..1171062) Ehrlichia canis str. Jake 3617755 YP_303464.1 CDS Ecaj_0835 NC_007354.1 1171878 1175681 R hypothetical protein complement(1171878..1175681) Ehrlichia canis str. Jake 3617756 YP_303465.1 CDS Ecaj_0836 NC_007354.1 1176292 1176552 R hypothetical protein complement(1176292..1176552) Ehrlichia canis str. Jake 3617757 YP_303466.1 CDS Ecaj_0837 NC_007354.1 1177587 1178624 R hypothetical protein complement(1177587..1178624) Ehrlichia canis str. Jake 3617758 YP_303467.1 CDS Ecaj_0838 NC_007354.1 1178924 1183456 R hypothetical protein complement(1178924..1183456) Ehrlichia canis str. Jake 3617759 YP_303468.1 CDS Ecaj_0839 NC_007354.1 1184275 1186650 R type IV secretion system protein VirB5 complement(1184275..1186650) Ehrlichia canis str. Jake 3617760 YP_303469.1 CDS Ecaj_0840 NC_007354.1 1187439 1187801 R hypothetical protein complement(1187439..1187801) Ehrlichia canis str. Jake 3617761 YP_303470.1 CDS Ecaj_0841 NC_007354.1 1187873 1188238 R hypothetical protein complement(1187873..1188238) Ehrlichia canis str. Jake 3617762 YP_303471.1 CDS Ecaj_0842 NC_007354.1 1189755 1190132 R hypothetical protein complement(1189755..1190132) Ehrlichia canis str. Jake 3617763 YP_303472.1 CDS Ecaj_0843 NC_007354.1 1190954 1192021 D HflK protein 1190954..1192021 Ehrlichia canis str. Jake 3617764 YP_303473.1 CDS Ecaj_0844 NC_007354.1 1192026 1192898 D hypothetical protein 1192026..1192898 Ehrlichia canis str. Jake 3617765 YP_303474.1 CDS Ecaj_0845 NC_007354.1 1192902 1194317 D peptidase S1 1192902..1194317 Ehrlichia canis str. Jake 3617766 YP_303475.1 CDS Ecaj_0846 NC_007354.1 1194319 1194900 D hypothetical protein 1194319..1194900 Ehrlichia canis str. Jake 3618237 YP_303476.1 CDS rnc NC_007354.1 1194907 1195587 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1194907..1195587 Ehrlichia canis str. Jake 3618238 YP_303477.1 CDS Ecaj_0848 NC_007354.1 1195584 1196108 D involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 1195584..1196108 Ehrlichia canis str. Jake 3618239 YP_303478.1 CDS Ecaj_0849 NC_007354.1 1196511 1197827 D insulinase-like:peptidase M16, C-terminal 1196511..1197827 Ehrlichia canis str. Jake 3618240 YP_303479.1 CDS Ecaj_0850 NC_007354.1 1197830 1199185 D insulinase-like:peptidase M16, C-terminal 1197830..1199185 Ehrlichia canis str. Jake 3618241 YP_303480.1 CDS Ecaj_0851 NC_007354.1 1199692 1200369 D hypothetical protein 1199692..1200369 Ehrlichia canis str. Jake 3618242 YP_303481.1 CDS Ecaj_0852 NC_007354.1 1200452 1200913 R signal peptidase II complement(1200452..1200913) Ehrlichia canis str. Jake 3618243 YP_303482.1 CDS Ecaj_0853 NC_007354.1 1200913 1201830 R FMN adenylyltransferase / riboflavin kinase complement(1200913..1201830) Ehrlichia canis str. Jake 3618244 YP_303483.1 CDS Ecaj_0854 NC_007354.1 1201902 1202147 D glutaredoxin 1201902..1202147 Ehrlichia canis str. Jake 3618245 YP_303484.1 CDS Ecaj_0855 NC_007354.1 1203071 1203913 R modification methylase HemK complement(1203071..1203913) Ehrlichia canis str. Jake 3618246 YP_303485.1 CDS Ecaj_0856 NC_007354.1 1203920 1204720 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(1203920..1204720) Ehrlichia canis str. Jake 3618247 YP_303486.1 CDS Ecaj_0857 NC_007354.1 1205663 1206865 R 2-oxoglutarate dehydrogenase E2 component complement(1205663..1206865) Ehrlichia canis str. Jake 3618248 YP_303487.1 CDS Ecaj_0858 NC_007354.1 1207686 1208204 R hexapaptide repeat-containing transferase complement(1207686..1208204) Ehrlichia canis str. Jake 3618249 YP_303488.1 CDS Ecaj_0859 NC_007354.1 1208489 1209640 D serine-type D-Ala-D-Ala carboxypeptidase 1208489..1209640 Ehrlichia canis str. Jake 3618250 YP_303489.1 CDS Ecaj_0860 NC_007354.1 1210258 1211487 R cytochrome c biogenesis protein, transmembrane region complement(1210258..1211487) Ehrlichia canis str. Jake 3618251 YP_303490.1 CDS Ecaj_0861 NC_007354.1 1211765 1212046 R hypothetical protein complement(1211765..1212046) Ehrlichia canis str. Jake 3618252 YP_303491.1 CDS Ecaj_0862 NC_007354.1 1212163 1213305 D peptidase RseP 1212163..1213305 Ehrlichia canis str. Jake 3618253 YP_303492.1 CDS Ecaj_0863 NC_007354.1 1213310 1215619 D surface antigen (D15):surface antigen variable number 1213310..1215619 Ehrlichia canis str. Jake 3618254 YP_303493.1 CDS Ecaj_0864 NC_007354.1 1215632 1216180 D hypothetical protein 1215632..1216180 Ehrlichia canis str. Jake 3618255 YP_303494.1 CDS fabZ NC_007354.1 1216202 1216648 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1216202..1216648 Ehrlichia canis str. Jake 3618417 YP_303495.1 CDS Ecaj_0866 NC_007354.1 1216681 1218195 D IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 1216681..1218195 Ehrlichia canis str. Jake 3618418 YP_303496.1 CDS Ecaj_0867 NC_007354.1 1219155 1219712 R CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(1219155..1219712) Ehrlichia canis str. Jake 3618419 YP_303497.1 CDS Ecaj_0868 NC_007354.1 1220004 1221314 D cytochrome c oxidase subunit I 1220004..1221314 Ehrlichia canis str. Jake 3618420 YP_303498.1 CDS Ecaj_0869 NC_007354.1 1222053 1222679 R hypothetical protein complement(1222053..1222679) Ehrlichia canis str. Jake 3618421 YP_303499.1 CDS Ecaj_0870 NC_007354.1 1223010 1224917 D pentapeptide repeat-containing protein 1223010..1224917 Ehrlichia canis str. Jake 3618422 YP_303500.1 CDS Ecaj_0871 NC_007354.1 1225524 1226783 R glycerol-1-phosphate dehydrogenase complement(1225524..1226783) Ehrlichia canis str. Jake 3618423 YP_303501.1 CDS Ecaj_0872 NC_007354.1 1227219 1227950 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1227219..1227950 Ehrlichia canis str. Jake 3618424 YP_303502.1 CDS Ecaj_0873 NC_007354.1 1228698 1228919 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1228698..1228919 Ehrlichia canis str. Jake 3618425 YP_303503.1 CDS Ecaj_0874 NC_007354.1 1228928 1229431 D H+-transporting two-sector ATPase subunit B/B' 1228928..1229431 Ehrlichia canis str. Jake 3618426 YP_303504.1 CDS Ecaj_0875 NC_007354.1 1229428 1229913 D hypothetical protein 1229428..1229913 Ehrlichia canis str. Jake 3618427 YP_303505.1 CDS Ecaj_0876 NC_007354.1 1229910 1231145 R cell division protein FtsA complement(1229910..1231145) Ehrlichia canis str. Jake 3618428 YP_303506.1 CDS Ecaj_0877 NC_007354.1 1231423 1232874 R cation transporter complement(1231423..1232874) Ehrlichia canis str. Jake 3618429 YP_303507.1 CDS Ecaj_0878 NC_007354.1 1233844 1235145 D cell cycle protein MesJ 1233844..1235145 Ehrlichia canis str. Jake 3618431 YP_303508.1 CDS Ecaj_0879 NC_007354.1 1235142 1236977 D FtsH peptidase 1235142..1236977 Ehrlichia canis str. Jake 3618432 YP_303509.1 CDS Ecaj_0880 NC_007354.1 1238731 1239516 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1238731..1239516) Ehrlichia canis str. Jake 3618433 YP_303510.1 CDS Ecaj_0881 NC_007354.1 1240088 1241005 D hypothetical protein 1240088..1241005 Ehrlichia canis str. Jake 3618434 YP_303511.1 CDS Ecaj_0882 NC_007354.1 1241340 1242923 R hypothetical protein complement(1241340..1242923) Ehrlichia canis str. Jake 3618435 YP_303512.1 CDS Ecaj_0884 NC_007354.1 1243795 1243956 R hypothetical protein complement(1243795..1243956) Ehrlichia canis str. Jake 3618526 YP_303513.1 CDS secD NC_007354.1 1243985 1245511 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(1243985..1245511) Ehrlichia canis str. Jake 3618527 YP_303514.1 CDS Ecaj_0885 NC_007354.1 1246329 1247111 R UBA/THIF-type NAD/FAD binding fold:MoeZ/MoeB complement(1246329..1247111) Ehrlichia canis str. Jake 3618528 YP_303515.1 CDS pyrE NC_007354.1 1247115 1247711 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(1247115..1247711) Ehrlichia canis str. Jake 3618529 YP_303516.1 CDS recA NC_007354.1 1247738 1248811 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1247738..1248811) Ehrlichia canis str. Jake 3618530 YP_303517.1 CDS Ecaj_0888 NC_007354.1 1249400 1250095 R dethiobiotin synthase complement(1249400..1250095) Ehrlichia canis str. Jake 3618531 YP_303518.1 CDS Ecaj_0889 NC_007354.1 1250171 1251103 D signal recognition particle-docking protein FtsY 1250171..1251103 Ehrlichia canis str. Jake 3618532 YP_303519.1 CDS Ecaj_0890 NC_007354.1 1251161 1252609 R catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase complement(1251161..1252609) Ehrlichia canis str. Jake 3618533 YP_303520.1 CDS Ecaj_0891 NC_007354.1 1252905 1254659 D RecJ exonuclease 1252905..1254659 Ehrlichia canis str. Jake 3618534 YP_303521.1 CDS Ecaj_0892 NC_007354.1 1256195 1257385 D polynucleotide adenylyl transferase 1256195..1257385 Ehrlichia canis str. Jake 3618535 YP_303522.1 CDS ndk NC_007354.1 1257837 1258274 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(1257837..1258274) Ehrlichia canis str. Jake 3618536 YP_303523.1 CDS Ecaj_0894 NC_007354.1 1258507 1259154 D transcriptional regulator 1258507..1259154 Ehrlichia canis str. Jake 3618537 YP_303524.1 CDS Ecaj_0895 NC_007354.1 1259382 1260272 D surface antigen msp4 1259382..1260272 Ehrlichia canis str. Jake 3618538 YP_303525.1 CDS Ecaj_0896 NC_007354.1 1261030 1261857 D surface antigen msp4 1261030..1261857 Ehrlichia canis str. Jake 3618392 YP_303526.1 CDS Ecaj_0897 NC_007354.1 1261964 1262410 D hypothetical protein 1261964..1262410 Ehrlichia canis str. Jake 3618393 YP_303527.1 CDS Ecaj_0898 NC_007354.1 1262421 1263371 D surface antigen msp4 1262421..1263371 Ehrlichia canis str. Jake 3618394 YP_303528.1 CDS Ecaj_0899 NC_007354.1 1263387 1264238 D surface antigen msp4 1263387..1264238 Ehrlichia canis str. Jake 3618395 YP_303529.1 CDS Ecaj_0900 NC_007354.1 1264255 1265049 D surface antigen msp4 1264255..1265049 Ehrlichia canis str. Jake 3618396 YP_303530.1 CDS Ecaj_0901 NC_007354.1 1265064 1265933 D surface antigen msp4 1265064..1265933 Ehrlichia canis str. Jake 3618397 YP_303531.1 CDS Ecaj_0902 NC_007354.1 1265958 1266794 D surface antigen msp4 1265958..1266794 Ehrlichia canis str. Jake 3618455 YP_303532.1 CDS Ecaj_0903 NC_007354.1 1266805 1267362 D hypothetical protein 1266805..1267362 Ehrlichia canis str. Jake 3618456 YP_303533.1 CDS Ecaj_0904 NC_007354.1 1267355 1268224 D surface antigen msp4 1267355..1268224 Ehrlichia canis str. Jake 3618457 YP_303534.1 CDS Ecaj_0905 NC_007354.1 1268233 1269072 D surface antigen msp4 1268233..1269072 Ehrlichia canis str. Jake 3618458 YP_303535.1 CDS Ecaj_0906 NC_007354.1 1269082 1269927 D surface antigen msp4 1269082..1269927 Ehrlichia canis str. Jake 3618459 YP_303536.1 CDS Ecaj_0907 NC_007354.1 1269950 1270849 D surface antigen msp4 1269950..1270849 Ehrlichia canis str. Jake 3618460 YP_303537.1 CDS Ecaj_0908 NC_007354.1 1270873 1271751 D surface antigen msp4 1270873..1271751 Ehrlichia canis str. Jake 3618461 YP_303538.1 CDS Ecaj_0909 NC_007354.1 1271764 1272648 D surface antigen msp4 1271764..1272648 Ehrlichia canis str. Jake 3618462 YP_303539.1 CDS Ecaj_0910 NC_007354.1 1272672 1273553 D surface antigen msp4 1272672..1273553 Ehrlichia canis str. Jake 3618463 YP_303540.1 CDS Ecaj_0911 NC_007354.1 1274101 1274943 D surface antigen msp4 1274101..1274943 Ehrlichia canis str. Jake 3618464 YP_303541.1 CDS Ecaj_0912 NC_007354.1 1275271 1276101 D surface antigen msp4 1275271..1276101 Ehrlichia canis str. Jake 3618465 YP_303542.1 CDS Ecaj_0913 NC_007354.1 1276312 1277175 D surface antigen msp4 1276312..1277175 Ehrlichia canis str. Jake 3618466 YP_303543.1 CDS Ecaj_0914 NC_007354.1 1277472 1278323 D surface antigen msp4 1277472..1278323 Ehrlichia canis str. Jake 3618467 YP_303544.1 CDS Ecaj_0915 NC_007354.1 1278666 1279508 D surface antigen msp4 1278666..1279508 Ehrlichia canis str. Jake 3618468 YP_303545.1 CDS Ecaj_0916 NC_007354.1 1279849 1280685 D surface antigen msp4 1279849..1280685 Ehrlichia canis str. Jake 3618469 YP_303546.1 CDS Ecaj_0917 NC_007354.1 1281037 1281903 D surface antigen msp4 1281037..1281903 Ehrlichia canis str. Jake 3618470 YP_303547.1 CDS Ecaj_0918 NC_007354.1 1282530 1283357 R major outer membrane protein P30- 20;surface antigen complement(1282530..1283357) Ehrlichia canis str. Jake 3618471 YP_303548.1 CDS Ecaj_0919 NC_007354.1 1284854 1285216 D hypothetical protein 1284854..1285216 Ehrlichia canis str. Jake 3618472 YP_303549.1 CDS Ecaj_0920 NC_007354.1 1285588 1286136 D hypothetical protein 1285588..1286136 Ehrlichia canis str. Jake 3618473 YP_303550.1 CDS secA NC_007354.1 1286475 1289063 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1286475..1289063 Ehrlichia canis str. Jake 3618474 YP_303551.1 CDS Ecaj_0922 NC_007354.1 1289739 1290140 R hypothetical protein complement(1289739..1290140) Ehrlichia canis str. Jake 3617854 YP_303552.1 CDS Ecaj_0923 NC_007354.1 1290358 1290912 R hypothetical protein complement(1290358..1290912) Ehrlichia canis str. Jake 3617855 YP_303553.1 CDS Ecaj_0924 NC_007354.1 1291213 1291647 R hypothetical protein complement(1291213..1291647) Ehrlichia canis str. Jake 3617856 YP_303554.1 CDS Ecaj_0925 NC_007354.1 1292028 1293290 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1292028..1293290 Ehrlichia canis str. Jake 3617857 YP_303555.1 CDS Ecaj_0926 NC_007354.1 1293297 1293704 D hypothetical protein 1293297..1293704 Ehrlichia canis str. Jake 3617858 YP_303556.1 CDS Ecaj_0927 NC_007354.1 1293701 1294165 D hypothetical protein 1293701..1294165 Ehrlichia canis str. Jake 3617859 YP_303557.1 CDS Ecaj_0928 NC_007354.1 1294544 1295311 D chromosome segregation ATPase 1294544..1295311 Ehrlichia canis str. Jake 3617860 YP_303558.1 CDS Ecaj_0929 NC_007354.1 1295324 1296175 D chromosome segregation DNA-binding protein 1295324..1296175 Ehrlichia canis str. Jake 3617861 YP_303559.1 CDS rimM NC_007354.1 1296288 1296809 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1296288..1296809 Ehrlichia canis str. Jake 3617862 YP_303560.1 CDS trmD NC_007354.1 1296799 1297506 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1296799..1297506 Ehrlichia canis str. Jake 3617863 YP_303561.1 CDS rplS NC_007354.1 1297499 1297876 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1297499..1297876 Ehrlichia canis str. Jake 3617864 YP_303562.1 CDS Ecaj_0933 NC_007354.1 1298118 1298600 R competence/damage-inducible protein cinA complement(1298118..1298600) Ehrlichia canis str. Jake 3617865 YP_303563.1 CDS thrS NC_007354.1 1298952 1300853 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1298952..1300853 Ehrlichia canis str. Jake 3617866 YP_303564.1 CDS Ecaj_0935 NC_007354.1 1300921 1301400 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1300921..1301400 Ehrlichia canis str. Jake 3617867 YP_303565.1 CDS Ecaj_0936 NC_007354.1 1304068 1304535 R hypothetical protein complement(1304068..1304535) Ehrlichia canis str. Jake 3617868 YP_303566.1 CDS Ecaj_0937 NC_007354.1 1304561 1305265 R hypothetical protein complement(1304561..1305265) Ehrlichia canis str. Jake 3617869 YP_303567.1 CDS Ecaj_0938 NC_007354.1 1305339 1306316 R hypothetical protein complement(1305339..1306316) Ehrlichia canis str. Jake 3617870 YP_303568.1 CDS Ecaj_0939 NC_007354.1 1306525 1307526 D glyceraldehyde-3-phosphate dehydrogenase 1306525..1307526 Ehrlichia canis str. Jake 3617871 YP_303569.1 CDS Ecaj_0940 NC_007354.1 1307857 1308516 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(1307857..1308516) Ehrlichia canis str. Jake 3617872 YP_303570.1 CDS Ecaj_0941 NC_007354.1 1308635 1309441 D pyrroline-5-carboxylate reductase 1308635..1309441 Ehrlichia canis str. Jake 3617572 YP_303571.1 CDS Ecaj_0942 NC_007354.1 1309631 1311106 D DNA-directed DNA polymerase 1309631..1311106 Ehrlichia canis str. Jake 3617574 YP_303572.1 CDS Ecaj_0943 NC_007354.1 1311121 1311426 D hypothetical protein 1311121..1311426 Ehrlichia canis str. Jake 3617575 YP_303573.1 CDS Ecaj_0944 NC_007354.1 1311438 1312448 D aspartate semialdehyde dehydrogenase 1311438..1312448 Ehrlichia canis str. Jake 3617576 YP_303574.1 CDS Ecaj_0945 NC_007354.1 1313490 1314671 R methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1313490..1314671) Ehrlichia canis str. Jake 3617577 Ecaj_R0001 tRNA Ecaj_R0001 NC_007354.1 338 415 D tRNA-Arg 338..415 Ehrlichia canis str. Jake 3617743 Ecaj_R0002 tRNA Ecaj_R0002 NC_007354.1 2234 2308 R tRNA-Gln complement(2234..2308) Ehrlichia canis str. Jake 3617746 Ecaj_R0003 tRNA Ecaj_R0003 NC_007354.1 27185 27275 R tRNA-Leu complement(27185..27275) Ehrlichia canis str. Jake 3618492 Ecaj_R0004 tRNA Ecaj_R0004 NC_007354.1 47712 47785 D tRNA-Val 47712..47785 Ehrlichia canis str. Jake 3618217 Ecaj_R0005 tRNA Ecaj_R0005 NC_007354.1 69588 69660 D tRNA-Lys 69588..69660 Ehrlichia canis str. Jake 3618359 Ecaj_R0006 tRNA Ecaj_R0006 NC_007354.1 75718 75792 R tRNA-Cys complement(75718..75792) Ehrlichia canis str. Jake 3618499 Ecaj_R0007 tRNA Ecaj_R0007 NC_007354.1 156010 156093 R tRNA-Leu complement(156010..156093) Ehrlichia canis str. Jake 3617994 Ecaj_R0008 tRNA Ecaj_R0008 NC_007354.1 167065 167143 D tRNA-Pro 167065..167143 Ehrlichia canis str. Jake 3618381 Ecaj_R0009 tRNA Ecaj_R0009 NC_007354.1 167568 167655 R tRNA-Ser complement(167568..167655) Ehrlichia canis str. Jake 3618509 Ecaj_R0010 tRNA Ecaj_R0010 NC_007354.1 190571 190643 D tRNA-Ala 190571..190643 Ehrlichia canis str. Jake 3618437 Ecaj_R0011 tRNA Ecaj_R0011 NC_007354.1 245349 245425 D tRNA-Trp 245349..245425 Ehrlichia canis str. Jake 3618361 Ecaj_R0012 tRNA Ecaj_R0012 NC_007354.1 259386 259459 D tRNA-Arg 259386..259459 Ehrlichia canis str. Jake 3618279 Ecaj_R0014 tRNA Ecaj_R0014 NC_007354.1 292601 292687 D tRNA-Leu 292601..292687 Ehrlichia canis str. Jake 3617633 Ecaj_R0015 tRNA Ecaj_R0015 NC_007354.1 300143 300215 D tRNA-Lys 300143..300215 Ehrlichia canis str. Jake 3617640 Ecaj_R0016 tRNA Ecaj_R0016 NC_007354.1 300396 300479 D tRNA-Leu 300396..300479 Ehrlichia canis str. Jake 3617641 Ecaj_R0017 tRNA Ecaj_R0017 NC_007354.1 307599 307673 D tRNA-Met 307599..307673 Ehrlichia canis str. Jake 3617646 Ecaj_R0018 tRNA Ecaj_R0018 NC_007354.1 360915 360990 D tRNA-Gly 360915..360990 Ehrlichia canis str. Jake 3618308 Ecaj_R0019 tRNA Ecaj_R0019 NC_007354.1 412218 412291 D tRNA-Asp 412218..412291 Ehrlichia canis str. Jake 3617653 Ecaj_R0021 tRNA Ecaj_R0021 NC_007354.1 489431 489503 R tRNA-Asn complement(489431..489503) Ehrlichia canis str. Jake 3618016 Ecaj_R0022 tRNA Ecaj_R0022 NC_007354.1 494191 494263 R tRNA-Phe complement(494191..494263) Ehrlichia canis str. Jake 3618020 Ecaj_R0023 tRNA Ecaj_R0023 NC_007354.1 503811 503887 R tRNA-Arg complement(503811..503887) Ehrlichia canis str. Jake 3618186 Ecaj_R0024 tRNA Ecaj_R0024 NC_007354.1 548477 548551 D tRNA-Met 548477..548551 Ehrlichia canis str. Jake 3617802 Ecaj_R0025 tRNA Ecaj_R0025 NC_007354.1 557852 557927 D tRNA-Met 557852..557927 Ehrlichia canis str. Jake 3617829 Ecaj_R0026 tRNA Ecaj_R0026 NC_007354.1 571075 571165 D tRNA-Ser 571075..571165 Ehrlichia canis str. Jake 3617571 Ecaj_R0027 tRNA Ecaj_R0027 NC_007354.1 592048 592120 D tRNA-Thr 592048..592120 Ehrlichia canis str. Jake 3617606 Ecaj_R0028 tRNA Ecaj_R0028 NC_007354.1 640728 640798 R tRNA-Thr complement(640728..640798) Ehrlichia canis str. Jake 3617779 Ecaj_R0029 tRNA Ecaj_R0029 NC_007354.1 668794 668877 D tRNA-Leu 668794..668877 Ehrlichia canis str. Jake 3618026 Ecaj_R0030 tRNA Ecaj_R0030 NC_007354.1 710743 710819 R tRNA-Ile complement(710743..710819) Ehrlichia canis str. Jake 3618480 Ecaj_R0031 tRNA Ecaj_R0031 NC_007354.1 727749 727825 R tRNA-Pro complement(727749..727825) Ehrlichia canis str. Jake 3617998 Ecaj_R0032 tRNA Ecaj_R0032 NC_007354.1 784352 784424 R tRNA-Arg complement(784352..784424) Ehrlichia canis str. Jake 3617958 Ecaj_R0033 tRNA Ecaj_R0033 NC_007354.1 825376 825448 R tRNA-Glu complement(825376..825448) Ehrlichia canis str. Jake 3617951 Ecaj_R0034 tRNA Ecaj_R0034 NC_007354.1 865093 865163 R tRNA-Gly complement(865093..865163) Ehrlichia canis str. Jake 3618073 Ecaj_R0035 tRNA Ecaj_R0035 NC_007354.1 865171 865253 R tRNA-Tyr complement(865171..865253) Ehrlichia canis str. Jake 3618074 Ecaj_R0037 tRNA Ecaj_R0037 NC_007354.1 958691 958763 R tRNA-Val complement(958691..958763) Ehrlichia canis str. Jake 3618259 Ecaj_R0040 tRNA Ecaj_R0040 NC_007354.1 1115358 1115430 R tRNA-His complement(1115358..1115430) Ehrlichia canis str. Jake 3617584 Ecaj_R0041 tRNA Ecaj_R0041 NC_007354.1 1233731 1233821 D tRNA-Ser 1233731..1233821 Ehrlichia canis str. Jake 3618430 Ecaj_R0013 rRNA Ecaj_R0013 NC_007354.1 285955 287439 D 16S ribosomal RNA 285955..287439 Ehrlichia canis str. Jake 3617626 Ecaj_R0038 rRNA Ecaj_R0038 NC_007354.1 1098799 1098918 R 5S ribosomal RNA complement(1098799..1098918) Ehrlichia canis str. Jake 3617716 Ecaj_R0039 rRNA Ecaj_R0039 NC_007354.1 1098983 1101781 R 23S ribosomal RNA complement(1098983..1101781) Ehrlichia canis str. Jake 3617717