-- dump date 20140619_070331 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_302650.1 73666634 3617744 475..1647 1 NC_007354.1 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 1647 3617744 Ecaj_0001 Ehrlichia canis str. Jake 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_302650.1 475 D 269484 CDS YP_302651.1 73666635 3617745 complement(1644..2204) 1 NC_007354.1 hypothetical protein 2204 3617745 Ecaj_0002 Ehrlichia canis str. Jake hypothetical protein YP_302651.1 1644 R 269484 CDS YP_302652.1 73666636 3618218 2588..3430 1 NC_007354.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 3430 glyQ 3618218 glyQ Ehrlichia canis str. Jake glycyl-tRNA synthetase subunit alpha YP_302652.1 2588 D 269484 CDS YP_302653.1 73666637 3618219 3446..5551 1 NC_007354.1 glycyl-tRNA synthetase subunit beta 5551 3618219 Ecaj_0004 Ehrlichia canis str. Jake glycyl-tRNA synthetase subunit beta YP_302653.1 3446 D 269484 CDS YP_302654.1 73666638 3618220 5613..6761 1 NC_007354.1 DnaJ central domain (CXXCXGXG):Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal; chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 6761 3618220 Ecaj_0005 Ehrlichia canis str. Jake chaperone protein DnaJ YP_302654.1 5613 D 269484 CDS YP_302655.1 73666639 3618221 complement(7496..8323) 1 NC_007354.1 nicotinate-nucleotide pyrophosphorylase 8323 3618221 Ecaj_0006 Ehrlichia canis str. Jake nicotinate-nucleotide pyrophosphorylase YP_302655.1 7496 R 269484 CDS YP_302656.1 73666640 3618222 8415..8990 1 NC_007354.1 membrane protein 8990 3618222 Ecaj_0007 Ehrlichia canis str. Jake membrane protein YP_302656.1 8415 D 269484 CDS YP_302657.1 73666641 3618223 complement(8996..9466) 1 NC_007354.1 Holliday junction endonuclease RuvC 9466 3618223 Ecaj_0008 Ehrlichia canis str. Jake Holliday junction endonuclease RuvC YP_302657.1 8996 R 269484 CDS YP_302658.1 73666642 3618224 complement(9468..10292) 1 NC_007354.1 cytochrome c oxidase subunit III 10292 3618224 Ecaj_0009 Ehrlichia canis str. Jake cytochrome c oxidase subunit III YP_302658.1 9468 R 269484 CDS YP_302659.1 73666643 3618225 complement(10390..11394) 1 NC_007354.1 uroporphyrinogen decarboxylase HemE 11394 3618225 Ecaj_0010 Ehrlichia canis str. Jake uroporphyrinogen decarboxylase HemE YP_302659.1 10390 R 269484 CDS YP_302660.1 73666644 3618226 11820..12707 1 NC_007354.1 CBS/transport-associated domain-containing protein 12707 3618226 Ecaj_0011 Ehrlichia canis str. Jake CBS/transport-associated domain-containing protein YP_302660.1 11820 D 269484 CDS YP_302661.1 73666645 3618227 complement(12690..13223) 1 NC_007354.1 prohead peptidase 13223 3618227 Ecaj_0012 Ehrlichia canis str. Jake prohead peptidase YP_302661.1 12690 R 269484 CDS YP_302662.1 73666646 3618228 complement(13333..14514) 1 NC_007354.1 HK97 family phage portal protein 14514 3618228 Ecaj_0013 Ehrlichia canis str. Jake HK97 family phage portal protein YP_302662.1 13333 R 269484 CDS YP_302663.1 73666647 3618229 14770..15531 1 NC_007354.1 putative methylase involved in ubiquinone/menaquinone biosynthesis 15531 3618229 Ecaj_0014 Ehrlichia canis str. Jake putative methylase involved in ubiquinone/menaquinone biosynthesis YP_302663.1 14770 D 269484 CDS YP_302664.1 73666648 3618230 15553..16494 1 NC_007354.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 16494 3618230 Ecaj_0015 Ehrlichia canis str. Jake quinolinate synthetase YP_302664.1 15553 D 269484 CDS YP_302665.1 73666649 3618231 complement(16694..17071) 1 NC_007354.1 4Fe-4S ferredoxin 17071 3618231 Ecaj_0016 Ehrlichia canis str. Jake 4Fe-4S ferredoxin YP_302665.1 16694 R 269484 CDS YP_302666.1 73666650 3618232 17335..19401 1 NC_007354.1 gp140 19401 3618232 Ecaj_0017 Ehrlichia canis str. Jake gp140 YP_302666.1 17335 D 269484 CDS YP_302667.1 73666651 3618233 complement(19831..22002) 1 NC_007354.1 type IV secretion system protein VirB8 22002 3618233 Ecaj_0018 Ehrlichia canis str. Jake type IV secretion system protein VirB8 YP_302667.1 19831 R 269484 CDS YP_302668.1 73666652 3618234 complement(22041..23039) 1 NC_007354.1 type IV secretion system ATPase VirB11 23039 3618234 Ecaj_0019 Ehrlichia canis str. Jake type IV secretion system ATPase VirB11 YP_302668.1 22041 R 269484 CDS YP_302669.1 73666653 3618235 complement(23056..24393) 1 NC_007354.1 conjugation TrbI-like protein 24393 3618235 Ecaj_0020 Ehrlichia canis str. Jake conjugation TrbI-like protein YP_302669.1 23056 R 269484 CDS YP_302670.1 73666654 3618236 complement(24415..25239) 1 NC_007354.1 conjugal transfer protein TrbG/VirB9/CagX 25239 3618236 Ecaj_0021 Ehrlichia canis str. Jake conjugal transfer protein TrbG/VirB9/CagX YP_302670.1 24415 R 269484 CDS YP_302671.1 73666655 3617558 complement(25226..25930) 1 NC_007354.1 virulence protein 25930 3617558 Ecaj_0022 Ehrlichia canis str. Jake virulence protein YP_302671.1 25226 R 269484 CDS YP_302672.1 73666656 3617559 complement(26023..27165) 1 NC_007354.1 GTP cyclohydrolase II 27165 3617559 Ecaj_0023 Ehrlichia canis str. Jake GTP cyclohydrolase II YP_302672.1 26023 R 269484 CDS YP_302673.1 73666657 3618493 complement(27624..28694) 1 NC_007354.1 hypothetical protein 28694 3618493 Ecaj_0024 Ehrlichia canis str. Jake hypothetical protein YP_302673.1 27624 R 269484 CDS YP_302674.1 73666658 3618508 complement(28769..29353) 1 NC_007354.1 hypothetical protein 29353 3618508 Ecaj_0025 Ehrlichia canis str. Jake hypothetical protein YP_302674.1 28769 R 269484 CDS YP_302675.1 73666659 3618494 complement(29334..30137) 1 NC_007354.1 diaminopimelate epimerase 30137 3618494 Ecaj_0026 Ehrlichia canis str. Jake diaminopimelate epimerase YP_302675.1 29334 R 269484 CDS YP_302676.1 73666660 3618205 complement(30388..30819) 1 NC_007354.1 hypothetical protein 30819 3618205 Ecaj_0027 Ehrlichia canis str. Jake hypothetical protein YP_302676.1 30388 R 269484 CDS YP_302677.1 73666661 3618206 31580..32764 1 NC_007354.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 32764 pgk 3618206 pgk Ehrlichia canis str. Jake phosphoglycerate kinase YP_302677.1 31580 D 269484 CDS YP_302678.1 73666662 3618207 complement(34033..35199) 1 NC_007354.1 exodeoxyribonuclease VII large subunit 35199 3618207 Ecaj_0029 Ehrlichia canis str. Jake exodeoxyribonuclease VII large subunit YP_302678.1 34033 R 269484 CDS YP_302679.1 73666663 3618208 complement(35196..35861) 1 NC_007354.1 hypothetical protein 35861 3618208 Ecaj_0030 Ehrlichia canis str. Jake hypothetical protein YP_302679.1 35196 R 269484 CDS YP_302680.2 161702949 3618209 36072..36911 1 NC_007354.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 36911 dapD 3618209 dapD Ehrlichia canis str. Jake 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_302680.2 36072 D 269484 CDS YP_302681.1 73666665 3618210 37192..38517 1 NC_007354.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 38517 trmE 3618210 trmE Ehrlichia canis str. Jake tRNA modification GTPase TrmE YP_302681.1 37192 D 269484 CDS YP_302682.1 73666666 3618211 complement(39861..40394) 1 NC_007354.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 40394 3618211 Ecaj_0033 Ehrlichia canis str. Jake phosphopantothenoylcysteine decarboxylase YP_302682.1 39861 R 269484 CDS YP_302683.1 73666667 3618212 40504..42540 1 NC_007354.1 DEAD/DEAH box helicase 42540 3618212 Ecaj_0034 Ehrlichia canis str. Jake DEAD/DEAH box helicase YP_302683.1 40504 D 269484 CDS YP_302684.1 73666668 3618213 43875..44837 1 NC_007354.1 NADH-ubiquinone oxidoreductase, putativ 44837 3618213 Ecaj_0035 Ehrlichia canis str. Jake NADH-ubiquinone oxidoreductase, putativ YP_302684.1 43875 D 269484 CDS YP_302685.1 73666669 3618214 complement(44951..45409) 1 NC_007354.1 dnaK suppressor protein 45409 3618214 Ecaj_0036 Ehrlichia canis str. Jake dnaK suppressor protein YP_302685.1 44951 R 269484 CDS YP_302686.1 73666670 3618215 45523..46185 1 NC_007354.1 heme exporter protein CcmB 46185 3618215 Ecaj_0037 Ehrlichia canis str. Jake heme exporter protein CcmB YP_302686.1 45523 D 269484 CDS YP_302687.1 73666671 3618216 47344..47586 1 NC_007354.1 hypothetical protein 47586 3618216 Ecaj_0038 Ehrlichia canis str. Jake hypothetical protein YP_302687.1 47344 D 269484 CDS YP_302688.1 73666672 3618127 47795..48733 1 NC_007354.1 cation efflux protein 48733 3618127 Ecaj_0039 Ehrlichia canis str. Jake cation efflux protein YP_302688.1 47795 D 269484 CDS YP_302689.1 73666673 3618128 49085..49714 1 NC_007354.1 putative ABC-type transport system involved in resistance to organic solvents auxiliary component 49714 3618128 Ecaj_0040 Ehrlichia canis str. Jake putative ABC-type transport system involved in resistance to organic solvents auxiliary component YP_302689.1 49085 D 269484 CDS YP_302690.1 73666674 3618129 complement(50131..50418) 1 NC_007354.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 50418 rpsT 3618129 rpsT Ehrlichia canis str. Jake 30S ribosomal protein S20 YP_302690.1 50131 R 269484 CDS YP_302691.1 73666675 3618130 complement(50579..51301) 1 NC_007354.1 phospholipid/glycerol acyltransferase 51301 3618130 Ecaj_0042 Ehrlichia canis str. Jake phospholipid/glycerol acyltransferase YP_302691.1 50579 R 269484 CDS YP_302692.1 73666676 3618131 52387..52944 1 NC_007354.1 peptide deformylase 52944 3618131 Ecaj_0043 Ehrlichia canis str. Jake peptide deformylase YP_302692.1 52387 D 269484 CDS YP_302693.1 73666677 3618132 52961..53746 1 NC_007354.1 DNA polymerase-like protein 53746 3618132 Ecaj_0044 Ehrlichia canis str. Jake DNA polymerase-like protein YP_302693.1 52961 D 269484 CDS YP_302694.1 73666678 3618133 complement(54279..55397) 1 NC_007354.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 55397 recF 3618133 recF Ehrlichia canis str. Jake recombination protein F YP_302694.1 54279 R 269484 CDS YP_302695.1 73666679 3618134 complement(56364..57275) 1 NC_007354.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 57275 3618134 Ecaj_0046 Ehrlichia canis str. Jake ornithine carbamoyltransferase YP_302695.1 56364 R 269484 CDS YP_302696.1 73666680 3618135 complement(57608..58009) 1 NC_007354.1 hypothetical protein 58009 3618135 Ecaj_0047 Ehrlichia canis str. Jake hypothetical protein YP_302696.1 57608 R 269484 CDS YP_302697.1 73666681 3618136 58330..60915 1 NC_007354.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 60915 3618136 Ecaj_0048 Ehrlichia canis str. Jake DNA polymerase I YP_302697.1 58330 D 269484 CDS YP_302698.1 73666682 3618137 61565..62233 1 NC_007354.1 ribulose-5-phosphate 3-epimerase 62233 3618137 Ecaj_0049 Ehrlichia canis str. Jake ribulose-5-phosphate 3-epimerase YP_302698.1 61565 D 269484 CDS YP_302699.1 73666683 3618138 62869..63666 1 NC_007354.1 hypothetical protein 63666 3618138 Ecaj_0050 Ehrlichia canis str. Jake hypothetical protein YP_302699.1 62869 D 269484 CDS YP_302700.1 73666684 3618139 63678..64394 1 NC_007354.1 ABC transporter 64394 3618139 Ecaj_0051 Ehrlichia canis str. Jake ABC transporter YP_302700.1 63678 D 269484 CDS YP_302701.1 73666685 3618504 64518..66359 1 NC_007354.1 ankyrin 66359 3618504 Ecaj_0052 Ehrlichia canis str. Jake ankyrin YP_302701.1 64518 D 269484 CDS YP_302702.1 73666686 3618357 complement(66806..67783) 1 NC_007354.1 trans-hexaprenyltrans transferase 67783 3618357 Ecaj_0053 Ehrlichia canis str. Jake trans-hexaprenyltrans transferase YP_302702.1 66806 R 269484 CDS YP_302703.1 73666687 3618358 complement(67973..69445) 1 NC_007354.1 L-glutamine synthetase 69445 3618358 Ecaj_0054 Ehrlichia canis str. Jake L-glutamine synthetase YP_302703.1 67973 R 269484 CDS YP_302704.1 73666688 3618475 69692..70948 1 NC_007354.1 tyrosyl-tRNA synthetase 70948 3618475 Ecaj_0055 Ehrlichia canis str. Jake tyrosyl-tRNA synthetase YP_302704.1 69692 D 269484 CDS YP_302705.1 73666689 3618476 70974..72170 1 NC_007354.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 72170 3618476 Ecaj_0056 Ehrlichia canis str. Jake 5-aminolevulinate synthase YP_302705.1 70974 D 269484 CDS YP_302706.1 73666690 3618477 complement(72177..72545) 1 NC_007354.1 hypothetical protein 72545 3618477 Ecaj_0057 Ehrlichia canis str. Jake hypothetical protein YP_302706.1 72177 R 269484 CDS YP_302707.1 73666691 3618478 73737..74618 1 NC_007354.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 74618 secF 3618478 secF Ehrlichia canis str. Jake preprotein translocase subunit SecF YP_302707.1 73737 D 269484 CDS YP_302708.1 73666692 3617831 complement(75792..76697) 1 NC_007354.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 76697 3617831 Ecaj_0059 Ehrlichia canis str. Jake fructose-bisphosphate aldolase YP_302708.1 75792 R 269484 CDS YP_302709.1 73666693 3617832 77108..88252 1 NC_007354.1 hypothetical protein 88252 3617832 Ecaj_0060 Ehrlichia canis str. Jake hypothetical protein YP_302709.1 77108 D 269484 CDS YP_302710.1 73666694 3617833 88390..89601 1 NC_007354.1 branched-chain alpha-keto acid dehydrogenase subunit E2 89601 3617833 Ecaj_0061 Ehrlichia canis str. Jake branched-chain alpha-keto acid dehydrogenase subunit E2 YP_302710.1 88390 D 269484 CDS YP_302711.1 73666695 3618500 90120..92993 1 NC_007354.1 hypothetical protein 92993 3618500 Ecaj_0062 Ehrlichia canis str. Jake hypothetical protein YP_302711.1 90120 D 269484 CDS YP_302712.1 73666696 3618501 93462..95579 1 NC_007354.1 hypothetical protein 95579 3618501 Ecaj_0063 Ehrlichia canis str. Jake hypothetical protein YP_302712.1 93462 D 269484 CDS YP_302713.1 73666697 3618502 95573..96256 1 NC_007354.1 hypothetical protein 96256 3618502 Ecaj_0064 Ehrlichia canis str. Jake hypothetical protein YP_302713.1 95573 D 269484 CDS YP_302714.1 73666698 3618503 96886..98673 1 NC_007354.1 hypothetical protein 98673 3618503 Ecaj_0065 Ehrlichia canis str. Jake hypothetical protein YP_302714.1 96886 D 269484 CDS YP_302715.1 73666699 3618100 99063..101732 1 NC_007354.1 hypothetical protein 101732 3618100 Ecaj_0066 Ehrlichia canis str. Jake hypothetical protein YP_302715.1 99063 D 269484 CDS YP_302716.1 73666700 3618101 102107..104194 1 NC_007354.1 hypothetical protein 104194 3618101 Ecaj_0067 Ehrlichia canis str. Jake hypothetical protein YP_302716.1 102107 D 269484 CDS YP_302717.1 73666701 3618102 104869..106719 1 NC_007354.1 hypothetical protein 106719 3618102 Ecaj_0068 Ehrlichia canis str. Jake hypothetical protein YP_302717.1 104869 D 269484 CDS YP_302718.1 73666702 3618103 107083..109554 1 NC_007354.1 hypothetical protein 109554 3618103 Ecaj_0069 Ehrlichia canis str. Jake hypothetical protein YP_302718.1 107083 D 269484 CDS YP_302719.1 73666703 3618104 109908..110144 1 NC_007354.1 hypothetical protein 110144 3618104 Ecaj_0070 Ehrlichia canis str. Jake hypothetical protein YP_302719.1 109908 D 269484 CDS YP_302720.1 73666704 3618105 110411..112336 1 NC_007354.1 hypothetical protein 112336 3618105 Ecaj_0071 Ehrlichia canis str. Jake hypothetical protein YP_302720.1 110411 D 269484 CDS YP_302721.1 73666705 3618106 112504..115254 1 NC_007354.1 hypothetical protein 115254 3618106 Ecaj_0072 Ehrlichia canis str. Jake hypothetical protein YP_302721.1 112504 D 269484 CDS YP_302722.1 73666706 3618398 complement(115413..115691) 1 NC_007354.1 hypothetical protein 115691 3618398 Ecaj_0073 Ehrlichia canis str. Jake hypothetical protein YP_302722.1 115413 R 269484 CDS YP_302723.1 73666707 3618399 116089..117669 1 NC_007354.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 117669 guaA 3618399 guaA Ehrlichia canis str. Jake GMP synthase YP_302723.1 116089 D 269484 CDS YP_302724.1 73666708 3618400 118602..119852 1 NC_007354.1 citrate synthase 119852 3618400 Ecaj_0075 Ehrlichia canis str. Jake citrate synthase YP_302724.1 118602 D 269484 CDS YP_302725.1 73666709 3618401 120137..121363 1 NC_007354.1 glutamate--cysteine ligase 121363 3618401 Ecaj_0076 Ehrlichia canis str. Jake glutamate--cysteine ligase YP_302725.1 120137 D 269484 CDS YP_302726.1 73666710 3618402 complement(122319..123323) 1 NC_007354.1 DNA polymerase III subunit delta 123323 3618402 Ecaj_0077 Ehrlichia canis str. Jake DNA polymerase III subunit delta YP_302726.1 122319 R 269484 CDS YP_302727.1 73666711 3618403 123620..124852 1 NC_007354.1 hypothetical protein 124852 3618403 Ecaj_0078 Ehrlichia canis str. Jake hypothetical protein YP_302727.1 123620 D 269484 CDS YP_302728.1 73666712 3618404 124865..125653 1 NC_007354.1 hypothetical protein 125653 3618404 Ecaj_0079 Ehrlichia canis str. Jake hypothetical protein YP_302728.1 124865 D 269484 CDS YP_302729.1 73666713 3618405 125650..126891 1 NC_007354.1 hypothetical protein 126891 3618405 Ecaj_0080 Ehrlichia canis str. Jake hypothetical protein YP_302729.1 125650 D 269484 CDS YP_302730.1 73666714 3618406 126897..127151 1 NC_007354.1 hypothetical protein 127151 3618406 Ecaj_0081 Ehrlichia canis str. Jake hypothetical protein YP_302730.1 126897 D 269484 CDS YP_302731.1 73666715 3618407 127933..128484 1 NC_007354.1 H+-transporting two-sector ATPase subunit delta 128484 3618407 Ecaj_0082 Ehrlichia canis str. Jake H+-transporting two-sector ATPase subunit delta YP_302731.1 127933 D 269484 CDS YP_302732.1 73666716 3618408 128497..130026 1 NC_007354.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 130026 3618408 Ecaj_0083 Ehrlichia canis str. Jake F0F1 ATP synthase subunit alpha YP_302732.1 128497 D 269484 CDS YP_302733.1 73666717 3618409 130038..130550 1 NC_007354.1 transcription elongation factor GreA 130550 3618409 Ecaj_0084 Ehrlichia canis str. Jake transcription elongation factor GreA YP_302733.1 130038 D 269484 CDS YP_302734.1 73666718 3618410 130568..131203 1 NC_007354.1 3,4-dihydroxy-2-butanone 4-phosphate synthase 131203 3618410 Ecaj_0085 Ehrlichia canis str. Jake 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_302734.1 130568 D 269484 CDS YP_302735.1 73666719 3618411 131225..131671 1 NC_007354.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 131671 smpB 3618411 smpB Ehrlichia canis str. Jake SsrA-binding protein YP_302735.1 131225 D 269484 CDS YP_302736.1 73666720 3618412 complement(133501..135435) 1 NC_007354.1 cytochrome c assembly protein 135435 3618412 Ecaj_0087 Ehrlichia canis str. Jake cytochrome c assembly protein YP_302736.1 133501 R 269484 CDS YP_302737.1 73666721 3618413 136407..138815 1 NC_007354.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 138815 valS 3618413 valS Ehrlichia canis str. Jake valyl-tRNA synthetase YP_302737.1 136407 D 269484 CDS YP_302738.1 73666722 3618414 139464..140300 1 NC_007354.1 glycine cleavage T protein(aminomethyl transferase) 140300 3618414 Ecaj_0089 Ehrlichia canis str. Jake glycine cleavage T protein(aminomethyl transferase) YP_302738.1 139464 D 269484 CDS YP_302739.1 73666723 3618415 complement(141348..142736) 1 NC_007354.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 142736 3618415 Ecaj_0090 Ehrlichia canis str. Jake amidophosphoribosyltransferase YP_302739.1 141348 R 269484 CDS YP_302740.1 73666724 3618416 complement(143984..144565) 1 NC_007354.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 144565 3618416 Ecaj_0091 Ehrlichia canis str. Jake peptidyl-tRNA hydrolase YP_302740.1 143984 R 269484 CDS YP_302741.1 73666725 3617986 complement(144576..145205) 1 NC_007354.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 145205 3617986 Ecaj_0092 Ehrlichia canis str. Jake 50S ribosomal protein L25/general stress protein Ctc YP_302741.1 144576 R 269484 CDS YP_302742.1 73666726 3617987 complement(146168..146860) 1 NC_007354.1 competence protein F 146860 3617987 Ecaj_0093 Ehrlichia canis str. Jake competence protein F YP_302742.1 146168 R 269484 CDS YP_302743.1 73666727 3617988 complement(146860..148029) 1 NC_007354.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 148029 3617988 Ecaj_0094 Ehrlichia canis str. Jake succinyl-diaminopimelate desuccinylase YP_302743.1 146860 R 269484 CDS YP_302744.1 73666728 3617989 complement(149269..150978) 1 NC_007354.1 hypothetical protein 150978 3617989 Ecaj_0095 Ehrlichia canis str. Jake hypothetical protein YP_302744.1 149269 R 269484 CDS YP_302745.1 73666729 3617990 complement(150988..151572) 1 NC_007354.1 hypothetical protein 151572 3617990 Ecaj_0096 Ehrlichia canis str. Jake hypothetical protein YP_302745.1 150988 R 269484 CDS YP_302746.1 73666730 3617991 complement(151677..152111) 1 NC_007354.1 hypothetical protein 152111 3617991 Ecaj_0097 Ehrlichia canis str. Jake hypothetical protein YP_302746.1 151677 R 269484 CDS YP_302747.1 73666731 3617992 complement(152787..153785) 1 NC_007354.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 153785 3617992 Ecaj_0098 Ehrlichia canis str. Jake pyruvate dehydrogenase subunit beta YP_302747.1 152787 R 269484 CDS YP_302748.1 73666732 3617993 complement(154086..155978) 1 NC_007354.1 hypothetical protein 155978 3617993 Ecaj_0099 Ehrlichia canis str. Jake hypothetical protein YP_302748.1 154086 R 269484 CDS YP_302749.1 73666733 3617995 156156..157589 1 NC_007354.1 microcin-processing peptidase 2 157589 3617995 Ecaj_0100 Ehrlichia canis str. Jake microcin-processing peptidase 2 YP_302749.1 156156 D 269484 CDS YP_302750.1 73666734 3618373 complement(158034..159122) 1 NC_007354.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 159122 3618373 Ecaj_0101 Ehrlichia canis str. Jake GTP-dependent nucleic acid-binding protein EngD YP_302750.1 158034 R 269484 CDS YP_302751.1 73666735 3618374 complement(160147..160668) 1 NC_007354.1 MECDP- synthase 160668 3618374 Ecaj_0102 Ehrlichia canis str. Jake MECDP- synthase YP_302751.1 160147 R 269484 CDS YP_302752.1 73666736 3618375 complement(161453..162148) 1 NC_007354.1 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 162148 3618375 Ecaj_0103 Ehrlichia canis str. Jake 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_302752.1 161453 R 269484 CDS YP_302753.1 73666737 3618376 163423..164700 1 NC_007354.1 hypothetical protein 164700 3618376 Ecaj_0104 Ehrlichia canis str. Jake hypothetical protein YP_302753.1 163423 D 269484 CDS YP_302754.1 73666738 3618377 complement(165017..165520) 1 NC_007354.1 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate(AIR) carboxylase 165520 3618377 Ecaj_0105 Ehrlichia canis str. Jake 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate(AIR) carboxylase YP_302754.1 165017 R 269484 CDS YP_302755.1 73666739 3618378 complement(165510..165956) 1 NC_007354.1 hypothetical protein 165956 3618378 Ecaj_0106 Ehrlichia canis str. Jake hypothetical protein YP_302755.1 165510 R 269484 CDS YP_302756.1 73666740 3618379 166385..166687 1 NC_007354.1 histone-like DNA-binding protein 166687 3618379 Ecaj_0107 Ehrlichia canis str. Jake histone-like DNA-binding protein YP_302756.1 166385 D 269484 CDS YP_302757.1 73666741 3618380 166700..167074 1 NC_007354.1 MerR family transcriptional regulator 167074 3618380 Ecaj_0108 Ehrlichia canis str. Jake MerR family transcriptional regulator YP_302757.1 166700 D 269484 CDS YP_302758.1 73666742 3618510 167903..168526 1 NC_007354.1 hypothetical protein 168526 3618510 Ecaj_0109 Ehrlichia canis str. Jake hypothetical protein YP_302758.1 167903 D 269484 CDS YP_302759.1 73666743 3618511 complement(169101..170102) 1 NC_007354.1 tryptophanyl-tRNA synthetase 170102 3618511 Ecaj_0110 Ehrlichia canis str. Jake tryptophanyl-tRNA synthetase YP_302759.1 169101 R 269484 CDS YP_302760.1 73666744 3618512 complement(170351..170950) 1 NC_007354.1 GrpE protein HSP-70 cofactor 170950 3618512 Ecaj_0111 Ehrlichia canis str. Jake GrpE protein HSP-70 cofactor YP_302760.1 170351 R 269484 CDS YP_302761.1 73666745 3618513 171058..172143 1 NC_007354.1 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase 172143 3618513 Ecaj_0112 Ehrlichia canis str. Jake 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase YP_302761.1 171058 D 269484 CDS YP_302762.1 73666746 3618514 172519..172932 1 NC_007354.1 major outer membrane protein p19 172932 3618514 Ecaj_0113 Ehrlichia canis str. Jake major outer membrane protein p19 YP_302762.1 172519 D 269484 CDS YP_302763.1 73666747 3618515 complement(173373..174989) 1 NC_007354.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 174989 pyrG 3618515 pyrG Ehrlichia canis str. Jake CTP synthetase YP_302763.1 173373 R 269484 CDS YP_302764.1 73666748 3618516 complement(174995..175327) 1 NC_007354.1 preprotein translocase subunit SecG 175327 secG 3618516 secG Ehrlichia canis str. Jake preprotein translocase subunit SecG YP_302764.1 174995 R 269484 CDS YP_302765.1 73666749 3618517 175648..176577 1 NC_007354.1 Phage integrase, N-terminal SAM- like 176577 3618517 Ecaj_0116 Ehrlichia canis str. Jake Phage integrase, N-terminal SAM- like YP_302765.1 175648 D 269484 CDS YP_302766.1 73666750 3618518 complement(177198..177878) 1 NC_007354.1 ABC transporter 177878 3618518 Ecaj_0117 Ehrlichia canis str. Jake ABC transporter YP_302766.1 177198 R 269484 CDS YP_302767.1 73666751 3618519 178681..180972 1 NC_007354.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 180972 3618519 Ecaj_0118 Ehrlichia canis str. Jake malic enzyme YP_302767.1 178681 D 269484 CDS YP_302768.1 73666752 3618520 181119..183764 1 NC_007354.1 hypothetical protein 183764 3618520 Ecaj_0119 Ehrlichia canis str. Jake hypothetical protein YP_302768.1 181119 D 269484 CDS YP_302769.1 73666753 3618521 complement(184817..186283) 1 NC_007354.1 apolipoprotein N-acyltransferase 186283 3618521 Ecaj_0120 Ehrlichia canis str. Jake apolipoprotein N-acyltransferase YP_302769.1 184817 R 269484 CDS YP_302770.1 73666754 3618522 187066..188541 1 NC_007354.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 188541 3618522 Ecaj_0121 Ehrlichia canis str. Jake putative monovalent cation/H+ antiporter subunit D YP_302770.1 187066 D 269484 CDS YP_302771.1 73666755 3618523 complement(188623..188934) 1 NC_007354.1 hypothetical protein 188934 3618523 Ecaj_0122 Ehrlichia canis str. Jake hypothetical protein YP_302771.1 188623 R 269484 CDS YP_302772.1 73666756 3618524 complement(189089..189538) 1 NC_007354.1 hypothetical protein 189538 3618524 Ecaj_0123 Ehrlichia canis str. Jake hypothetical protein YP_302772.1 189089 R 269484 CDS YP_302773.1 73666757 3618525 complement(189559..189858) 1 NC_007354.1 putative NADH:ubiquinone oxidoreductase 17.2kD subunit 189858 3618525 Ecaj_0124 Ehrlichia canis str. Jake putative NADH:ubiquinone oxidoreductase 17.2kD subunit YP_302773.1 189559 R 269484 CDS YP_302774.1 73666758 3618436 189989..190450 1 NC_007354.1 transcriptional regulator NrdR 190450 nrdR 3618436 nrdR Ehrlichia canis str. Jake transcriptional regulator NrdR YP_302774.1 189989 D 269484 CDS YP_302775.1 73666759 3618438 complement(190710..192725) 1 NC_007354.1 hypothetical protein 192725 3618438 Ecaj_0126 Ehrlichia canis str. Jake hypothetical protein YP_302775.1 190710 R 269484 CDS YP_302776.1 73666760 3618439 193233..196250 1 NC_007354.1 surface protein-like protein 196250 3618439 Ecaj_0127 Ehrlichia canis str. Jake surface protein-like protein YP_302776.1 193233 D 269484 CDS YP_302777.1 73666761 3618440 196640..197683 1 NC_007354.1 extracellular solute-binding protein 197683 3618440 Ecaj_0128 Ehrlichia canis str. Jake extracellular solute-binding protein YP_302777.1 196640 D 269484 CDS YP_302778.1 73666762 3618441 complement(198532..198795) 1 NC_007354.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 198795 rpsP 3618441 rpsP Ehrlichia canis str. Jake 30S ribosomal protein S16 YP_302778.1 198532 R 269484 CDS YP_302779.1 73666763 3618442 198987..200312 1 NC_007354.1 general substrate transporter 200312 3618442 Ecaj_0130 Ehrlichia canis str. Jake general substrate transporter YP_302779.1 198987 D 269484 CDS YP_302780.1 73666764 3618443 complement(200746..200916) 1 NC_007354.1 hypothetical protein 200916 3618443 Ecaj_0131 Ehrlichia canis str. Jake hypothetical protein YP_302780.1 200746 R 269484 CDS YP_302781.1 73666765 3618444 complement(201810..202505) 1 NC_007354.1 short-chain alchohol deydrogenase 202505 3618444 Ecaj_0132 Ehrlichia canis str. Jake short-chain alchohol deydrogenase YP_302781.1 201810 R 269484 CDS YP_302782.1 73666766 3618445 complement(202507..203544) 1 NC_007354.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 203544 pheS 3618445 pheS Ehrlichia canis str. Jake phenylalanyl-tRNA synthetase subunit alpha YP_302782.1 202507 R 269484 CDS YP_302783.1 73666767 3618446 complement(203531..203905) 1 NC_007354.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 203905 rplT 3618446 rplT Ehrlichia canis str. Jake 50S ribosomal protein L20 YP_302783.1 203531 R 269484 CDS YP_302784.1 73666768 3618447 complement(203931..204131) 1 NC_007354.1 50S ribosomal protein L35 204131 rpmI 3618447 rpmI Ehrlichia canis str. Jake 50S ribosomal protein L35 YP_302784.1 203931 R 269484 CDS YP_302785.1 73666769 3618448 204483..205124 1 NC_007354.1 hypothetical protein 205124 3618448 Ecaj_0136 Ehrlichia canis str. Jake hypothetical protein YP_302785.1 204483 D 269484 CDS YP_302786.1 73666770 3618449 205559..206989 1 NC_007354.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 206989 rho 3618449 rho Ehrlichia canis str. Jake transcription termination factor Rho YP_302786.1 205559 D 269484 CDS YP_302787.1 73666771 3618450 complement(208939..210414) 1 NC_007354.1 dihydrolipoamide dehydrogenase 210414 3618450 Ecaj_0138 Ehrlichia canis str. Jake dihydrolipoamide dehydrogenase YP_302787.1 208939 R 269484 CDS YP_302788.1 73666772 3618451 210619..213003 1 NC_007354.1 hypothetical protein 213003 3618451 Ecaj_0139 Ehrlichia canis str. Jake hypothetical protein YP_302788.1 210619 D 269484 CDS YP_302789.1 73666773 3618452 213426..214874 1 NC_007354.1 hypothetical protein 214874 3618452 Ecaj_0140 Ehrlichia canis str. Jake hypothetical protein YP_302789.1 213426 D 269484 CDS YP_302790.1 73666774 3618453 214874..215506 1 NC_007354.1 hypothetical protein 215506 3618453 Ecaj_0141 Ehrlichia canis str. Jake hypothetical protein YP_302790.1 214874 D 269484 CDS YP_302791.1 73666775 3618454 215496..216032 1 NC_007354.1 hypothetical protein 216032 3618454 Ecaj_0142 Ehrlichia canis str. Jake hypothetical protein YP_302791.1 215496 D 269484 CDS YP_302792.1 73666776 3618286 216299..217093 1 NC_007354.1 Beta-lactamase-like 217093 3618286 Ecaj_0143 Ehrlichia canis str. Jake Beta-lactamase-like YP_302792.1 216299 D 269484 CDS YP_302793.1 73666777 3618287 complement(217840..218640) 1 NC_007354.1 glutamine synthetase 218640 3618287 Ecaj_0144 Ehrlichia canis str. Jake glutamine synthetase YP_302793.1 217840 R 269484 CDS YP_302794.1 73666778 3618288 complement(218647..219771) 1 NC_007354.1 binding-protein dependent transport system inner membrane protein 219771 3618288 Ecaj_0145 Ehrlichia canis str. Jake binding-protein dependent transport system inner membrane protein YP_302794.1 218647 R 269484 CDS YP_302795.1 73666779 3618289 219915..222590 1 NC_007354.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 222590 alaS 3618289 alaS Ehrlichia canis str. Jake alanyl-tRNA synthetase YP_302795.1 219915 D 269484 CDS YP_302796.1 73666780 3618290 complement(224882..225769) 1 NC_007354.1 succinyl-CoA synthetase subunit alpha 225769 3618290 Ecaj_0147 Ehrlichia canis str. Jake succinyl-CoA synthetase subunit alpha YP_302796.1 224882 R 269484 CDS YP_302797.1 73666781 3618291 complement(225777..226937) 1 NC_007354.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 226937 sucC 3618291 sucC Ehrlichia canis str. Jake succinyl-CoA synthetase subunit beta YP_302797.1 225777 R 269484 CDS YP_302798.1 73666782 3618292 complement(227018..227293) 1 NC_007354.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 227293 rpsU 3618292 rpsU Ehrlichia canis str. Jake 30S ribosomal protein S21 YP_302798.1 227018 R 269484 CDS YP_302799.1 73666783 3618293 complement(227439..228461) 1 NC_007354.1 phosphate ABC transporter substrate-binding protein 228461 3618293 Ecaj_0150 Ehrlichia canis str. Jake phosphate ABC transporter substrate-binding protein YP_302799.1 227439 R 269484 CDS YP_302800.1 73666784 3618294 complement(228521..229138) 1 NC_007354.1 electron transport protein SCO1/SenC 229138 3618294 Ecaj_0151 Ehrlichia canis str. Jake electron transport protein SCO1/SenC YP_302800.1 228521 R 269484 CDS YP_302801.1 73666785 3618295 complement(229443..230480) 1 NC_007354.1 2-nitropropane dioxygenase 230480 3618295 Ecaj_0152 Ehrlichia canis str. Jake 2-nitropropane dioxygenase YP_302801.1 229443 R 269484 CDS YP_302802.1 73666786 3618296 complement(230489..231010) 1 NC_007354.1 nickel-dependent hydrogenase b- type cytochrome subunit 231010 3618296 Ecaj_0153 Ehrlichia canis str. Jake nickel-dependent hydrogenase b- type cytochrome subunit YP_302802.1 230489 R 269484 CDS YP_302803.1 73666787 3618297 231165..232784 1 NC_007354.1 binding-protein dependent transport system inner membrane protein 232784 3618297 Ecaj_0154 Ehrlichia canis str. Jake binding-protein dependent transport system inner membrane protein YP_302803.1 231165 D 269484 CDS YP_302804.1 73666788 3618298 complement(233991..235508) 1 NC_007354.1 Type I secretion membrane fusion protein, HlyD 235508 3618298 Ecaj_0155 Ehrlichia canis str. Jake Type I secretion membrane fusion protein, HlyD YP_302804.1 233991 R 269484 CDS YP_302805.1 73666789 3618540 complement(235887..236504) 1 NC_007354.1 hypothetical protein 236504 3618540 Ecaj_0156 Ehrlichia canis str. Jake hypothetical protein YP_302805.1 235887 R 269484 CDS YP_302806.1 73666790 3618505 complement(237293..238927) 1 NC_007354.1 Beta-lactamase-like 238927 3618505 Ecaj_0157 Ehrlichia canis str. Jake Beta-lactamase-like YP_302806.1 237293 R 269484 CDS YP_302807.1 73666791 3618140 239591..240886 1 NC_007354.1 metallophosphoesterase 240886 3618140 Ecaj_0158 Ehrlichia canis str. Jake metallophosphoesterase YP_302807.1 239591 D 269484 CDS YP_302808.1 73666792 3617740 241157..241528 1 NC_007354.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 241528 rpsL 3617740 rpsL Ehrlichia canis str. Jake 30S ribosomal protein S12 YP_302808.1 241157 D 269484 CDS YP_302809.1 73666793 3617741 241544..242026 1 NC_007354.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 242026 3617741 Ecaj_0160 Ehrlichia canis str. Jake 30S ribosomal protein S7 YP_302809.1 241544 D 269484 CDS YP_302810.1 73666794 3617742 242048..244120 1 NC_007354.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 244120 3617742 Ecaj_0161 Ehrlichia canis str. Jake elongation factor G YP_302810.1 242048 D 269484 CDS YP_302811.1 73666795 3618360 244136..245323 1 NC_007354.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 245323 3618360 Ecaj_0162 Ehrlichia canis str. Jake elongation factor Tu YP_302811.1 244136 D 269484 CDS YP_302812.1 73666796 3618362 245462..245659 1 NC_007354.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 245659 secE 3618362 secE Ehrlichia canis str. Jake preprotein translocase subunit SecE YP_302812.1 245462 D 269484 CDS YP_302813.1 73666797 3618363 245649..246194 1 NC_007354.1 transcription antitermination protein NusG 246194 3618363 Ecaj_0164 Ehrlichia canis str. Jake transcription antitermination protein NusG YP_302813.1 245649 D 269484 CDS YP_302814.1 73666798 3618364 246191..246634 1 NC_007354.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 246634 rplK 3618364 rplK Ehrlichia canis str. Jake 50S ribosomal protein L11 YP_302814.1 246191 D 269484 CDS YP_302815.1 73666799 3618365 246660..247322 1 NC_007354.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 247322 rplA 3618365 rplA Ehrlichia canis str. Jake 50S ribosomal protein L1 YP_302815.1 246660 D 269484 CDS YP_302816.1 73666800 3618366 247339..247821 1 NC_007354.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 247821 rplJ 3618366 rplJ Ehrlichia canis str. Jake 50S ribosomal protein L10 YP_302816.1 247339 D 269484 CDS YP_302817.1 73666801 3618367 247877..248275 1 NC_007354.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 248275 rplL 3618367 rplL Ehrlichia canis str. Jake 50S ribosomal protein L7/L12 YP_302817.1 247877 D 269484 CDS YP_302818.1 73666802 3618368 248323..252465 1 NC_007354.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 252465 rpoB 3618368 rpoB Ehrlichia canis str. Jake DNA-directed RNA polymerase subunit beta YP_302818.1 248323 D 269484 CDS YP_302819.1 73666803 3618369 252485..256717 1 NC_007354.1 DNA-directed RNA polymerase 256717 3618369 Ecaj_0170 Ehrlichia canis str. Jake DNA-directed RNA polymerase YP_302819.1 252485 D 269484 CDS YP_302820.1 73666804 3618370 257736..258839 1 NC_007354.1 8-amino-7-oxononanoate synthase 258839 3618370 Ecaj_0171 Ehrlichia canis str. Jake 8-amino-7-oxononanoate synthase YP_302820.1 257736 D 269484 CDS YP_302821.1 73666805 3618280 259486..259902 1 NC_007354.1 hypothetical protein 259902 3618280 Ecaj_0172 Ehrlichia canis str. Jake hypothetical protein YP_302821.1 259486 D 269484 CDS YP_302822.1 73666806 3618281 complement(260433..261062) 1 NC_007354.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 261062 rnhB 3618281 rnhB Ehrlichia canis str. Jake ribonuclease HII YP_302822.1 260433 R 269484 CDS YP_302823.1 73666807 3618282 262012..265932 1 NC_007354.1 hypothetical protein 265932 3618282 Ecaj_0174 Ehrlichia canis str. Jake hypothetical protein YP_302823.1 262012 D 269484 CDS YP_302824.1 73666808 3618283 complement(266383..266859) 1 NC_007354.1 hypothetical protein 266859 3618283 Ecaj_0175 Ehrlichia canis str. Jake hypothetical protein YP_302824.1 266383 R 269484 CDS YP_302825.1 73666809 3618284 266996..267592 1 NC_007354.1 hypothetical protein 267592 3618284 Ecaj_0176 Ehrlichia canis str. Jake hypothetical protein YP_302825.1 266996 D 269484 CDS YP_302826.1 73666810 3618285 complement(268577..269371) 1 NC_007354.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 269371 3618285 Ecaj_0177 Ehrlichia canis str. Jake pantothenate kinase YP_302826.1 268577 R 269484 CDS YP_302827.1 73666811 3617615 complement(269381..270433) 1 NC_007354.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 270433 3617615 Ecaj_0178 Ehrlichia canis str. Jake dihydroorotate dehydrogenase 2 YP_302827.1 269381 R 269484 CDS YP_302828.1 73666812 3617616 270596..271180 1 NC_007354.1 formylmethionine deformylase 271180 3617616 Ecaj_0179 Ehrlichia canis str. Jake formylmethionine deformylase YP_302828.1 270596 D 269484 CDS YP_302829.1 73666813 3617617 complement(271824..273239) 1 NC_007354.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 273239 3617617 Ecaj_0180 Ehrlichia canis str. Jake argininosuccinate lyase YP_302829.1 271824 R 269484 CDS YP_302830.1 73666814 3617618 273597..274238 1 NC_007354.1 phospholipase/carboxylesterase 274238 3617618 Ecaj_0181 Ehrlichia canis str. Jake phospholipase/carboxylesterase YP_302830.1 273597 D 269484 CDS YP_302831.1 73666815 3617619 274636..275583 1 NC_007354.1 patatin 275583 3617619 Ecaj_0182 Ehrlichia canis str. Jake patatin YP_302831.1 274636 D 269484 CDS YP_302832.1 73666816 3617620 276018..276611 1 NC_007354.1 pyridoxamine 5'-phosphate oxidase 276611 3617620 Ecaj_0183 Ehrlichia canis str. Jake pyridoxamine 5'-phosphate oxidase YP_302832.1 276018 D 269484 CDS YP_302833.1 73666817 3617621 complement(277368..277661) 1 NC_007354.1 BolA-like protein 277661 3617621 Ecaj_0184 Ehrlichia canis str. Jake BolA-like protein YP_302833.1 277368 R 269484 CDS YP_302834.1 73666818 3617622 277934..278749 1 NC_007354.1 hypothetical protein 278749 3617622 Ecaj_0185 Ehrlichia canis str. Jake hypothetical protein YP_302834.1 277934 D 269484 CDS YP_302835.1 73666819 3617623 279307..280164 1 NC_007354.1 hypothetical protein 280164 3617623 Ecaj_0186 Ehrlichia canis str. Jake hypothetical protein YP_302835.1 279307 D 269484 CDS YP_302836.1 73666820 3617624 280752..284123 1 NC_007354.1 DNA polymerase III subunit alpha 284123 3617624 Ecaj_0187 Ehrlichia canis str. Jake DNA polymerase III subunit alpha YP_302836.1 280752 D 269484 CDS YP_302837.1 73666821 3617625 284417..285703 1 NC_007354.1 3-phosphoshikimate 1-carboxyvinyltransferase 285703 3617625 Ecaj_0188 Ehrlichia canis str. Jake 3-phosphoshikimate 1-carboxyvinyltransferase YP_302837.1 284417 D 269484 CDS YP_302838.1 73666822 3617627 287591..288001 1 NC_007354.1 succinate dehydrogenase subunit C 288001 3617627 Ecaj_0189 Ehrlichia canis str. Jake succinate dehydrogenase subunit C YP_302838.1 287591 D 269484 CDS YP_302839.1 73666823 3617628 288016..288372 1 NC_007354.1 succinate dehydrogenase subunit D 288372 3617628 Ecaj_0190 Ehrlichia canis str. Jake succinate dehydrogenase subunit D YP_302839.1 288016 D 269484 CDS YP_302840.1 73666824 3617629 288595..289860 1 NC_007354.1 hypothetical protein 289860 3617629 Ecaj_0191 Ehrlichia canis str. Jake hypothetical protein YP_302840.1 288595 D 269484 CDS YP_302841.1 73666825 3617630 complement(290127..290936) 1 NC_007354.1 phosphomethylpyrimidine kinase 290936 3617630 Ecaj_0192 Ehrlichia canis str. Jake phosphomethylpyrimidine kinase YP_302841.1 290127 R 269484 CDS YP_302842.1 73666826 3617631 complement(290929..291585) 1 NC_007354.1 chromosomal DNA replication initiator-like protein 291585 3617631 Ecaj_0193 Ehrlichia canis str. Jake chromosomal DNA replication initiator-like protein YP_302842.1 290929 R 269484 CDS YP_302843.1 73666827 3617632 291984..292592 1 NC_007354.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 292592 rpsD 3617632 rpsD Ehrlichia canis str. Jake 30S ribosomal protein S4 YP_302843.1 291984 D 269484 CDS YP_302844.1 73666828 3617635 293905..295026 1 NC_007354.1 hypothetical protein 295026 3617635 Ecaj_0196 Ehrlichia canis str. Jake hypothetical protein YP_302844.1 293905 D 269484 CDS YP_302845.1 73666829 3617636 296904..297104 1 NC_007354.1 hypothetical protein 297104 3617636 Ecaj_0197 Ehrlichia canis str. Jake hypothetical protein YP_302845.1 296904 D 269484 CDS YP_302846.1 73666830 3617637 complement(297137..298282) 1 NC_007354.1 hypothetical protein 298282 3617637 Ecaj_0198 Ehrlichia canis str. Jake hypothetical protein YP_302846.1 297137 R 269484 CDS YP_302847.1 73666831 3617638 complement(298324..299109) 1 NC_007354.1 N-acetyltransferase GCN5 299109 3617638 Ecaj_0199 Ehrlichia canis str. Jake N-acetyltransferase GCN5 YP_302847.1 298324 R 269484 CDS YP_302848.1 73666832 3617639 complement(299111..299617) 1 NC_007354.1 phosphatidylglycerophosphatase A 299617 3617639 Ecaj_0200 Ehrlichia canis str. Jake phosphatidylglycerophosphatase A YP_302848.1 299111 R 269484 CDS YP_302849.1 73666833 3617642 300507..301829 1 NC_007354.1 trigger factor 301829 3617642 Ecaj_0201 Ehrlichia canis str. Jake trigger factor YP_302849.1 300507 D 269484 CDS YP_302850.1 73666834 3617643 301900..302502 1 NC_007354.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 302502 clpP 3617643 clpP Ehrlichia canis str. Jake ATP-dependent Clp protease proteolytic subunit YP_302850.1 301900 D 269484 CDS YP_302851.1 73666835 3617644 302515..303735 1 NC_007354.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 303735 clpX 3617644 clpX Ehrlichia canis str. Jake ATP-dependent protease ATP-binding subunit ClpX YP_302851.1 302515 D 269484 CDS YP_302852.1 73666836 3617645 303745..306150 1 NC_007354.1 Lon-A peptidase 306150 3617645 Ecaj_0204 Ehrlichia canis str. Jake Lon-A peptidase YP_302852.1 303745 D 269484 CDS YP_302853.1 73666837 3617647 307914..308825 1 NC_007354.1 methionyl-tRNA formyltransferase 308825 3617647 Ecaj_0205 Ehrlichia canis str. Jake methionyl-tRNA formyltransferase YP_302853.1 307914 D 269484 CDS YP_302854.1 73666838 3617685 309074..309898 1 NC_007354.1 rhodanese-like protein 309898 3617685 Ecaj_0206 Ehrlichia canis str. Jake rhodanese-like protein YP_302854.1 309074 D 269484 CDS YP_302855.1 73666839 3617686 310419..311240 1 NC_007354.1 hypothetical protein 311240 3617686 Ecaj_0207 Ehrlichia canis str. Jake hypothetical protein YP_302855.1 310419 D 269484 CDS YP_302856.1 73666840 3617687 complement(311580..312629) 1 NC_007354.1 thiamine monophosphate synthase 312629 3617687 Ecaj_0208 Ehrlichia canis str. Jake thiamine monophosphate synthase YP_302856.1 311580 R 269484 CDS YP_302857.1 73666841 3617689 complement(313905..315191) 1 NC_007354.1 hypothetical protein 315191 3617689 Ecaj_0210 Ehrlichia canis str. Jake hypothetical protein YP_302857.1 313905 R 269484 CDS YP_302858.1 73666842 3617690 315330..315614 1 NC_007354.1 hypothetical protein 315614 3617690 Ecaj_0211 Ehrlichia canis str. Jake hypothetical protein YP_302858.1 315330 D 269484 CDS YP_302859.1 73666843 3617691 315622..318168 1 NC_007354.1 cell division protein FtsK 318168 3617691 Ecaj_0212 Ehrlichia canis str. Jake cell division protein FtsK YP_302859.1 315622 D 269484 CDS YP_302860.1 73666844 3617692 complement(319716..320702) 1 NC_007354.1 hypothetical protein 320702 3617692 Ecaj_0213 Ehrlichia canis str. Jake hypothetical protein YP_302860.1 319716 R 269484 CDS YP_302861.1 73666845 3617693 complement(320826..322001) 1 NC_007354.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase protein 322001 argD 3617693 argD Ehrlichia canis str. Jake acetylornithine transaminase protein YP_302861.1 320826 R 269484 CDS YP_302862.1 73666846 3617694 322158..323570 1 NC_007354.1 sensor histidine kinase 323570 3617694 Ecaj_0215 Ehrlichia canis str. Jake sensor histidine kinase YP_302862.1 322158 D 269484 CDS YP_302863.1 73666847 3617695 323844..325892 1 NC_007354.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 325892 mutL 3617695 mutL Ehrlichia canis str. Jake DNA mismatch repair protein YP_302863.1 323844 D 269484 CDS YP_302864.1 73666848 3617696 complement(327012..328136) 1 NC_007354.1 SMF protein 328136 3617696 Ecaj_0217 Ehrlichia canis str. Jake SMF protein YP_302864.1 327012 R 269484 CDS YP_302865.1 73666849 3617697 complement(328362..329630) 1 NC_007354.1 3-oxoacyl-ACP synthase 329630 3617697 Ecaj_0218 Ehrlichia canis str. Jake 3-oxoacyl-ACP synthase YP_302865.1 328362 R 269484 CDS YP_302866.1 73666850 3617698 complement(329646..329921) 1 NC_007354.1 acyl carrier protein 329921 3617698 Ecaj_0219 Ehrlichia canis str. Jake acyl carrier protein YP_302866.1 329646 R 269484 CDS YP_302867.1 73666851 3617699 complement(331084..332469) 1 NC_007354.1 hypothetical protein 332469 3617699 Ecaj_0220 Ehrlichia canis str. Jake hypothetical protein YP_302867.1 331084 R 269484 CDS YP_302868.1 73666852 3617700 332842..335643 1 NC_007354.1 ankyrin 335643 3617700 Ecaj_0221 Ehrlichia canis str. Jake ankyrin YP_302868.1 332842 D 269484 CDS YP_302869.2 161702948 3617701 complement(335621..335791) 1 NC_007354.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 335791 rpmG 3617701 rpmG Ehrlichia canis str. Jake 50S ribosomal protein L33 YP_302869.2 335621 R 269484 CDS YP_302870.1 73666854 3617702 335965..336672 1 NC_007354.1 hypothetical protein 336672 3617702 Ecaj_0223 Ehrlichia canis str. Jake hypothetical protein YP_302870.1 335965 D 269484 CDS YP_302871.1 73666855 3617703 336677..337156 1 NC_007354.1 disulfide bond formation protein DsbB 337156 3617703 Ecaj_0224 Ehrlichia canis str. Jake disulfide bond formation protein DsbB YP_302871.1 336677 D 269484 CDS YP_302872.1 73666856 3617704 337140..337652 1 NC_007354.1 Coq7 family protein 337652 3617704 Ecaj_0225 Ehrlichia canis str. Jake Coq7 family protein YP_302872.1 337140 D 269484 CDS YP_302873.1 73666857 3617648 complement(338795..339898) 1 NC_007354.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 339898 mnmA 3617648 mnmA Ehrlichia canis str. Jake tRNA-specific 2-thiouridylase MnmA YP_302873.1 338795 R 269484 CDS YP_302874.1 73666858 3617649 complement(340369..341379) 1 NC_007354.1 putative Tfp pilus assembly proteinpilusretraction ATPase PilT 341379 3617649 Ecaj_0227 Ehrlichia canis str. Jake putative Tfp pilus assembly proteinpilusretraction ATPase PilT YP_302874.1 340369 R 269484 CDS YP_302875.1 73666859 3617650 complement(341789..342826) 1 NC_007354.1 hypothetical protein 342826 3617650 Ecaj_0228 Ehrlichia canis str. Jake hypothetical protein YP_302875.1 341789 R 269484 CDS YP_302876.1 73666860 3617894 complement(343048..344112) 1 NC_007354.1 hypothetical protein 344112 3617894 Ecaj_0229 Ehrlichia canis str. Jake hypothetical protein YP_302876.1 343048 R 269484 CDS YP_302877.1 73666861 3618299 complement(344162..345622) 1 NC_007354.1 hypothetical protein 345622 3618299 Ecaj_0230 Ehrlichia canis str. Jake hypothetical protein YP_302877.1 344162 R 269484 CDS YP_302878.1 73666862 3618300 complement(345933..346919) 1 NC_007354.1 hypothetical protein 346919 3618300 Ecaj_0231 Ehrlichia canis str. Jake hypothetical protein YP_302878.1 345933 R 269484 CDS YP_302879.1 73666863 3618301 complement(347891..349129) 1 NC_007354.1 hypothetical protein 349129 3618301 Ecaj_0232 Ehrlichia canis str. Jake hypothetical protein YP_302879.1 347891 R 269484 CDS YP_302880.1 73666864 3618302 complement(349422..351341) 1 NC_007354.1 ATP-dependent DNA helicase Rep 351341 3618302 Ecaj_0233 Ehrlichia canis str. Jake ATP-dependent DNA helicase Rep YP_302880.1 349422 R 269484 CDS YP_302881.1 73666865 3618303 351788..354484 1 NC_007354.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 354484 3618303 Ecaj_0234 Ehrlichia canis str. Jake DNA gyrase subunit A YP_302881.1 351788 D 269484 CDS YP_302882.1 73666866 3618304 354502..355140 1 NC_007354.1 DNA-(apurinic or apyrimidinic site) lyase 355140 3618304 Ecaj_0235 Ehrlichia canis str. Jake DNA-(apurinic or apyrimidinic site) lyase YP_302882.1 354502 D 269484 CDS YP_302883.1 73666867 3618305 355252..355854 1 NC_007354.1 hypothetical protein 355854 3618305 Ecaj_0236 Ehrlichia canis str. Jake hypothetical protein YP_302883.1 355252 D 269484 CDS YP_302884.1 73666868 3618306 355925..357838 1 NC_007354.1 molecular chaperone; heat shock protein 90 357838 3618306 Ecaj_0237 Ehrlichia canis str. Jake heat shock protein 90 YP_302884.1 355925 D 269484 CDS YP_302885.1 73666869 3618307 complement(359333..360634) 1 NC_007354.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 360634 3618307 Ecaj_0238 Ehrlichia canis str. Jake adenylosuccinate lyase YP_302885.1 359333 R 269484 CDS YP_302886.1 73666870 3618309 complement(361476..364331) 1 NC_007354.1 hypothetical protein 364331 3618309 Ecaj_0239 Ehrlichia canis str. Jake hypothetical protein YP_302886.1 361476 R 269484 CDS YP_302887.1 73666871 3618310 complement(365011..365754) 1 NC_007354.1 biotin--acetyl-CoA-carboxylase ligase 365754 3618310 Ecaj_0240 Ehrlichia canis str. Jake biotin--acetyl-CoA-carboxylase ligase YP_302887.1 365011 R 269484 CDS YP_302888.1 73666872 3618311 complement(366308..366985) 1 NC_007354.1 glutathione S-transferase 366985 3618311 Ecaj_0241 Ehrlichia canis str. Jake glutathione S-transferase YP_302888.1 366308 R 269484 CDS YP_302889.1 73666873 3618312 complement(367354..367863) 1 NC_007354.1 hypothetical protein 367863 3618312 Ecaj_0242 Ehrlichia canis str. Jake hypothetical protein YP_302889.1 367354 R 269484 CDS YP_302890.1 73666874 3618333 368171..369193 1 NC_007354.1 ABC transporter 369193 3618333 Ecaj_0243 Ehrlichia canis str. Jake ABC transporter YP_302890.1 368171 D 269484 CDS YP_302891.1 73666875 3618334 369219..369389 1 NC_007354.1 twin-arginine translocation protein TatA/E 369389 3618334 Ecaj_0244 Ehrlichia canis str. Jake twin-arginine translocation protein TatA/E YP_302891.1 369219 D 269484 CDS YP_302892.1 73666876 3618335 369630..370217 1 NC_007354.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 370217 recR 3618335 recR Ehrlichia canis str. Jake recombination protein RecR YP_302892.1 369630 D 269484 CDS YP_302893.1 73666877 3618338 complement(371058..371921) 1 NC_007354.1 periplasmic solute binding protein 371921 3618338 Ecaj_0248 Ehrlichia canis str. Jake periplasmic solute binding protein YP_302893.1 371058 R 269484 CDS YP_302894.1 73666878 3618339 371988..372641 1 NC_007354.1 ABC transporter 372641 3618339 Ecaj_0249 Ehrlichia canis str. Jake ABC transporter YP_302894.1 371988 D 269484 CDS YP_302895.1 73666879 3618340 372634..374076 1 NC_007354.1 2-octaprenylphenol hydroxylase 374076 3618340 Ecaj_0250 Ehrlichia canis str. Jake 2-octaprenylphenol hydroxylase YP_302895.1 372634 D 269484 CDS YP_302896.1 73666880 3618341 374860..376065 1 NC_007354.1 major facilitator family transporter 376065 3618341 Ecaj_0251 Ehrlichia canis str. Jake major facilitator family transporter YP_302896.1 374860 D 269484 CDS YP_302897.1 73666881 3618342 complement(377146..378471) 1 NC_007354.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 378471 3618342 Ecaj_0252 Ehrlichia canis str. Jake (dimethylallyl)adenosine tRNA methylthiotransferase YP_302897.1 377146 R 269484 CDS YP_302898.1 73666882 3618343 complement(379361..382981) 1 NC_007354.1 hypothetical protein 382981 3618343 Ecaj_0253 Ehrlichia canis str. Jake hypothetical protein YP_302898.1 379361 R 269484 CDS YP_302899.1 73666883 3618344 complement(383839..384648) 1 NC_007354.1 hypothetical protein 384648 3618344 Ecaj_0254 Ehrlichia canis str. Jake hypothetical protein YP_302899.1 383839 R 269484 CDS YP_302900.1 73666884 3618345 385384..388122 1 NC_007354.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 388122 sucA 3618345 sucA Ehrlichia canis str. Jake 2-oxoglutarate dehydrogenase E1 component YP_302900.1 385384 D 269484 CDS YP_302901.1 73666885 3618346 complement(388484..389632) 1 NC_007354.1 HK97 family phage major capsid protein 389632 3618346 Ecaj_0256 Ehrlichia canis str. Jake HK97 family phage major capsid protein YP_302901.1 388484 R 269484 CDS YP_302902.1 73666886 3618347 complement(390168..391058) 1 NC_007354.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 391058 3618347 Ecaj_0257 Ehrlichia canis str. Jake dihydrodipicolinate synthase YP_302902.1 390168 R 269484 CDS YP_302903.1 73666887 3618348 complement(391759..392112) 1 NC_007354.1 histidine triad (HIT) protein 392112 3618348 Ecaj_0258 Ehrlichia canis str. Jake histidine triad (HIT) protein YP_302903.1 391759 R 269484 CDS YP_302904.1 73666888 3618349 complement(392099..393205) 1 NC_007354.1 hypothetical protein 393205 3618349 Ecaj_0259 Ehrlichia canis str. Jake hypothetical protein YP_302904.1 392099 R 269484 CDS YP_302905.1 73666889 3618350 393396..395810 1 NC_007354.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 395810 3618350 Ecaj_0260 Ehrlichia canis str. Jake DNA mismatch repair protein MutS YP_302905.1 393396 D 269484 CDS YP_302906.1 73666890 3618351 complement(396969..398486) 1 NC_007354.1 NAD+ synthase 398486 3618351 Ecaj_0261 Ehrlichia canis str. Jake NAD+ synthase YP_302906.1 396969 R 269484 CDS YP_302907.1 73666891 3618352 complement(398874..399866) 1 NC_007354.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 399866 3618352 Ecaj_0262 Ehrlichia canis str. Jake delta-aminolevulinic acid dehydratase YP_302907.1 398874 R 269484 CDS YP_302908.1 73666892 3618353 400081..402816 1 NC_007354.1 hypothetical protein 402816 3618353 Ecaj_0263 Ehrlichia canis str. Jake hypothetical protein YP_302908.1 400081 D 269484 CDS YP_302909.1 73666893 3618354 403389..404636 1 NC_007354.1 general substrate transporter 404636 3618354 Ecaj_0264 Ehrlichia canis str. Jake general substrate transporter YP_302909.1 403389 D 269484 CDS YP_302910.1 73666894 3618355 405490..406725 1 NC_007354.1 general substrate transporter 406725 3618355 Ecaj_0265 Ehrlichia canis str. Jake general substrate transporter YP_302910.1 405490 D 269484 CDS YP_302911.1 73666895 3618356 complement(407640..408113) 1 NC_007354.1 single-strand binding protein 408113 3618356 Ecaj_0266 Ehrlichia canis str. Jake single-strand binding protein YP_302911.1 407640 R 269484 CDS YP_302912.1 73666896 3617651 408264..409640 1 NC_007354.1 malonyl-CoA decarboxylase 409640 3617651 Ecaj_0267 Ehrlichia canis str. Jake malonyl-CoA decarboxylase YP_302912.1 408264 D 269484 CDS YP_302913.1 73666897 3617652 409673..411121 1 NC_007354.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 411121 gatB 3617652 gatB Ehrlichia canis str. Jake aspartyl/glutamyl-tRNA amidotransferase subunit B YP_302913.1 409673 D 269484 CDS YP_302914.1 73666898 3617654 412352..413194 1 NC_007354.1 enoyl-(acyl carrier protein) reductase 413194 3617654 Ecaj_0269 Ehrlichia canis str. Jake enoyl-(acyl carrier protein) reductase YP_302914.1 412352 D 269484 CDS YP_302915.1 73666899 3617655 413518..414876 1 NC_007354.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 414876 dnaA 3617655 dnaA Ehrlichia canis str. Jake chromosomal replication initiation protein YP_302915.1 413518 D 269484 CDS YP_302916.1 73666900 3617656 complement(415695..416684) 1 NC_007354.1 hypothetical protein 416684 3617656 Ecaj_0271 Ehrlichia canis str. Jake hypothetical protein YP_302916.1 415695 R 269484 CDS YP_302917.1 73666901 3617657 417252..417836 1 NC_007354.1 cytidyltransferase-like protein 417836 3617657 Ecaj_0272 Ehrlichia canis str. Jake cytidyltransferase-like protein YP_302917.1 417252 D 269484 CDS YP_302918.1 73666902 3617658 417898..418614 1 NC_007354.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 418614 3617658 Ecaj_0273 Ehrlichia canis str. Jake pyridoxine 5'-phosphate synthase YP_302918.1 417898 D 269484 CDS YP_302919.1 73666903 3617659 complement(418611..418895) 1 NC_007354.1 histone-like DNA-binding protein 418895 3617659 Ecaj_0274 Ehrlichia canis str. Jake histone-like DNA-binding protein YP_302919.1 418611 R 269484 CDS YP_302920.1 73666904 3617660 complement(419237..420127) 1 NC_007354.1 ATPase 420127 3617660 Ecaj_0275 Ehrlichia canis str. Jake ATPase YP_302920.1 419237 R 269484 CDS YP_302921.1 73666905 3617661 complement(420732..421328) 1 NC_007354.1 translation factor SUA5 421328 3617661 Ecaj_0276 Ehrlichia canis str. Jake translation factor SUA5 YP_302921.1 420732 R 269484 CDS YP_302922.1 73666906 3617662 421559..422161 1 NC_007354.1 dephospho-CoA kinase 422161 3617662 Ecaj_0277 Ehrlichia canis str. Jake dephospho-CoA kinase YP_302922.1 421559 D 269484 CDS YP_302923.1 73666907 3617663 complement(423245..424942) 1 NC_007354.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 424942 3617663 Ecaj_0278 Ehrlichia canis str. Jake thiamine biosynthesis protein ThiC YP_302923.1 423245 R 269484 CDS YP_302924.1 73666908 3617664 complement(425082..425696) 1 NC_007354.1 Smr protein/MutS2 C-terminal 425696 3617664 Ecaj_0279 Ehrlichia canis str. Jake Smr protein/MutS2 C-terminal YP_302924.1 425082 R 269484 CDS YP_302925.1 73666909 3617665 complement(425785..426201) 1 NC_007354.1 RNA polymerase subunit omega 426201 3617665 Ecaj_0280 Ehrlichia canis str. Jake RNA polymerase subunit omega YP_302925.1 425785 R 269484 CDS YP_302926.1 73666910 3617666 complement(426290..426616) 1 NC_007354.1 hypothetical protein 426616 3617666 Ecaj_0281 Ehrlichia canis str. Jake hypothetical protein YP_302926.1 426290 R 269484 CDS YP_302927.1 73666911 3617667 427109..429598 1 NC_007354.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 429598 leuS 3617667 leuS Ehrlichia canis str. Jake leucyl-tRNA synthetase YP_302927.1 427109 D 269484 CDS YP_302928.1 73666912 3617668 430208..430990 1 NC_007354.1 TatD-related deoxyribonuclease 430990 3617668 Ecaj_0283 Ehrlichia canis str. Jake TatD-related deoxyribonuclease YP_302928.1 430208 D 269484 CDS YP_302929.1 73666913 3617669 431252..431938 1 NC_007354.1 orotidine-5'-phosphate decarboxylase 431938 3617669 Ecaj_0284 Ehrlichia canis str. Jake orotidine-5'-phosphate decarboxylase YP_302929.1 431252 D 269484 CDS YP_302930.1 73666914 3617670 432275..433045 1 NC_007354.1 5'-nucleotidase 433045 3617670 Ecaj_0285 Ehrlichia canis str. Jake 5'-nucleotidase YP_302930.1 432275 D 269484 CDS YP_302931.1 73666915 3617671 433160..433561 1 NC_007354.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 433561 3617671 Ecaj_0286 Ehrlichia canis str. Jake cytochrome c-type biogenesis protein CcmE YP_302931.1 433160 D 269484 CDS YP_302932.1 73666916 3617672 complement(434052..434630) 1 NC_007354.1 NADH (or F420H2) dehydrogenase subunit C 434630 3617672 Ecaj_0287 Ehrlichia canis str. Jake NADH (or F420H2) dehydrogenase subunit C YP_302932.1 434052 R 269484 CDS YP_302933.1 73666917 3617673 complement(434945..435502) 1 NC_007354.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 435502 3617673 Ecaj_0288 Ehrlichia canis str. Jake NADH dehydrogenase subunit B YP_302933.1 434945 R 269484 CDS YP_302934.1 73666918 3617674 complement(435493..435864) 1 NC_007354.1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 435864 3617674 Ecaj_0289 Ehrlichia canis str. Jake NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_302934.1 435493 R 269484 CDS YP_302935.1 73666919 3617675 complement(436200..439052) 1 NC_007354.1 excinuclease ABC subunit A 439052 3617675 Ecaj_0290 Ehrlichia canis str. Jake excinuclease ABC subunit A YP_302935.1 436200 R 269484 CDS YP_302936.1 73666920 3617676 complement(439307..439753) 1 NC_007354.1 hypothetical protein 439753 3617676 Ecaj_0291 Ehrlichia canis str. Jake hypothetical protein YP_302936.1 439307 R 269484 CDS YP_302937.1 73666921 3617677 complement(439842..440288) 1 NC_007354.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 440288 ribH 3617677 ribH Ehrlichia canis str. Jake 6,7-dimethyl-8-ribityllumazine synthase YP_302937.1 439842 R 269484 CDS YP_302938.1 73666922 3617678 complement(440290..442029) 1 NC_007354.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 442029 3617678 Ecaj_0293 Ehrlichia canis str. Jake putative inner membrane protein translocase component YidC YP_302938.1 440290 R 269484 CDS YP_302939.1 73666923 3617679 complement(442364..443746) 1 NC_007354.1 Sodium:alanine symporter 443746 3617679 Ecaj_0294 Ehrlichia canis str. Jake Sodium:alanine symporter YP_302939.1 442364 R 269484 CDS YP_302940.1 73666924 3617680 complement(443768..444547) 1 NC_007354.1 CDP-alcohol phosphatidyltransferase 444547 3617680 Ecaj_0295 Ehrlichia canis str. Jake CDP-alcohol phosphatidyltransferase YP_302940.1 443768 R 269484 CDS YP_302941.1 73666925 3617681 complement(444557..445237) 1 NC_007354.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 445237 3617681 Ecaj_0296 Ehrlichia canis str. Jake phosphatidylserine decarboxylase YP_302941.1 444557 R 269484 CDS YP_302942.1 73666926 3617682 complement(445901..449293) 1 NC_007354.1 hypothetical protein 449293 3617682 Ecaj_0297 Ehrlichia canis str. Jake hypothetical protein YP_302942.1 445901 R 269484 CDS YP_302943.1 73666927 3617723 450462..451031 1 NC_007354.1 translation elongation factor P (EF-P) 451031 3617723 Ecaj_0301 Ehrlichia canis str. Jake translation elongation factor P (EF-P) YP_302943.1 450462 D 269484 CDS YP_302944.1 73666928 3617724 451215..451982 1 NC_007354.1 inositol monophosphatase family protein 451982 3617724 Ecaj_0302 Ehrlichia canis str. Jake inositol monophosphatase family protein YP_302944.1 451215 D 269484 CDS YP_302945.1 73666929 3617725 452678..453604 1 NC_007354.1 ribosomal large subunit pseudouridine synthase C 453604 3617725 Ecaj_0303 Ehrlichia canis str. Jake ribosomal large subunit pseudouridine synthase C YP_302945.1 452678 D 269484 CDS YP_302946.1 73666930 3617726 complement(454189..455565) 1 NC_007354.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD 455565 pleD 3617726 pleD Ehrlichia canis str. Jake response regulator PleD YP_302946.1 454189 R 269484 CDS YP_302947.1 73666931 3617727 complement(455580..455846) 1 NC_007354.1 hypothetical protein 455846 3617727 Ecaj_0305 Ehrlichia canis str. Jake hypothetical protein YP_302947.1 455580 R 269484 CDS YP_302948.1 73666932 3617728 complement(455858..460606) 1 NC_007354.1 glutamate dehydrogenase 460606 3617728 Ecaj_0306 Ehrlichia canis str. Jake glutamate dehydrogenase YP_302948.1 455858 R 269484 CDS YP_302949.1 73666933 3617729 461148..461777 1 NC_007354.1 exopolysaccharide synthesis, ExoD 461777 3617729 Ecaj_0307 Ehrlichia canis str. Jake exopolysaccharide synthesis, ExoD YP_302949.1 461148 D 269484 CDS YP_302950.1 73666934 3617730 461774..463153 1 NC_007354.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 463153 cysS 3617730 cysS Ehrlichia canis str. Jake cysteinyl-tRNA synthetase YP_302950.1 461774 D 269484 CDS YP_302951.1 73666935 3617731 complement(464082..466604) 1 NC_007354.1 hypothetical protein 466604 3617731 Ecaj_0309 Ehrlichia canis str. Jake hypothetical protein YP_302951.1 464082 R 269484 CDS YP_302952.1 73666936 3617732 466928..467902 1 NC_007354.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 467902 nrdF 3617732 nrdF Ehrlichia canis str. Jake ribonucleotide-diphosphate reductase subunit beta YP_302952.1 466928 D 269484 CDS YP_302953.1 73666937 3617733 complement(468768..469037) 1 NC_007354.1 hypothetical protein 469037 3617733 Ecaj_0311 Ehrlichia canis str. Jake hypothetical protein YP_302953.1 468768 R 269484 CDS YP_302954.1 73666938 3617734 complement(469042..469608) 1 NC_007354.1 hypothetical protein 469608 3617734 Ecaj_0312 Ehrlichia canis str. Jake hypothetical protein YP_302954.1 469042 R 269484 CDS YP_302955.1 73666939 3617735 469679..470686 1 NC_007354.1 hypothetical protein 470686 3617735 Ecaj_0313 Ehrlichia canis str. Jake hypothetical protein YP_302955.1 469679 D 269484 CDS YP_302956.1 73666940 3617736 471248..473062 1 NC_007354.1 DNA primase 473062 3617736 Ecaj_0314 Ehrlichia canis str. Jake DNA primase YP_302956.1 471248 D 269484 CDS YP_302957.1 73666941 3617737 complement(474557..476425) 1 NC_007354.1 RNA polymerase sigma factor rpoD 476425 3617737 Ecaj_0315 Ehrlichia canis str. Jake RNA polymerase sigma factor rpoD YP_302957.1 474557 R 269484 CDS YP_302958.1 73666942 3617738 complement(476569..477522) 1 NC_007354.1 dihydrouridine synthase TIM-barrel protein nifR3 477522 3617738 Ecaj_0316 Ehrlichia canis str. Jake dihydrouridine synthase TIM-barrel protein nifR3 YP_302958.1 476569 R 269484 CDS YP_302959.1 73666943 3617739 477954..478802 1 NC_007354.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 478802 3617739 Ecaj_0317 Ehrlichia canis str. Jake 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_302959.1 477954 D 269484 CDS YP_302960.1 73666944 3617834 complement(479325..479645) 1 NC_007354.1 CutA1 divalent ion tolerance protein 479645 3617834 Ecaj_0318 Ehrlichia canis str. Jake CutA1 divalent ion tolerance protein YP_302960.1 479325 R 269484 CDS YP_302961.1 73666945 3617892 complement(479754..482228) 1 NC_007354.1 response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal 482228 3617892 Ecaj_0319 Ehrlichia canis str. Jake response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal YP_302961.1 479754 R 269484 CDS YP_302962.1 73666946 3617893 complement(482362..483021) 1 NC_007354.1 O-methyltransferase family protein 483021 3617893 Ecaj_0320 Ehrlichia canis str. Jake O-methyltransferase family protein YP_302962.1 482362 R 269484 CDS YP_302963.1 73666947 3618010 483257..483556 1 NC_007354.1 hypothetical protein 483556 3618010 Ecaj_0321 Ehrlichia canis str. Jake hypothetical protein YP_302963.1 483257 D 269484 CDS YP_302964.1 73666948 3618011 483645..485045 1 NC_007354.1 sugar kinase 485045 3618011 Ecaj_0322 Ehrlichia canis str. Jake sugar kinase YP_302964.1 483645 D 269484 CDS YP_302965.1 73666949 3618012 485455..487917 1 NC_007354.1 DNA topoisomerase I 487917 3618012 Ecaj_0323 Ehrlichia canis str. Jake DNA topoisomerase I YP_302965.1 485455 D 269484 CDS YP_302966.1 73666950 3618013 complement(487980..488333) 1 NC_007354.1 hypothetical protein 488333 3618013 Ecaj_0324 Ehrlichia canis str. Jake hypothetical protein YP_302966.1 487980 R 269484 CDS YP_302967.1 73666951 3618014 complement(488503..488976) 1 NC_007354.1 hypothetical protein 488976 3618014 Ecaj_0325 Ehrlichia canis str. Jake hypothetical protein YP_302967.1 488503 R 269484 CDS YP_302968.1 73666952 3618017 complement(490470..490850) 1 NC_007354.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 490850 acpS 3618017 acpS Ehrlichia canis str. Jake 4'-phosphopantetheinyl transferase YP_302968.1 490470 R 269484 CDS YP_302969.1 73666953 3618018 complement(490847..492121) 1 NC_007354.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 492121 3618018 Ecaj_0327 Ehrlichia canis str. Jake prolyl-tRNA synthetase YP_302969.1 490847 R 269484 CDS YP_302970.1 73666954 3618019 complement(493135..494100) 1 NC_007354.1 hypothetical protein 494100 3618019 Ecaj_0328 Ehrlichia canis str. Jake hypothetical protein YP_302970.1 493135 R 269484 CDS YP_302971.1 73666955 3618021 494436..494924 1 NC_007354.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 494924 coaD 3618021 coaD Ehrlichia canis str. Jake phosphopantetheine adenylyltransferase YP_302971.1 494436 D 269484 CDS YP_302972.1 73666956 3618023 complement(496308..497273) 1 NC_007354.1 thioredoxin reductase 497273 3618023 Ecaj_0331 Ehrlichia canis str. Jake thioredoxin reductase YP_302972.1 496308 R 269484 CDS YP_302973.1 73666957 3618024 complement(497274..497891) 1 NC_007354.1 alkyl hydroperoxide reductase/thiol specific antioxidant/ Mal allergen 497891 3618024 Ecaj_0332 Ehrlichia canis str. Jake alkyl hydroperoxide reductase/thiol specific antioxidant/ Mal allergen YP_302973.1 497274 R 269484 CDS YP_302974.1 73666958 3618183 498313..499509 1 NC_007354.1 aminotransferase 499509 3618183 Ecaj_0333 Ehrlichia canis str. Jake aminotransferase YP_302974.1 498313 D 269484 CDS YP_302975.1 73666959 3618184 complement(500883..502775) 1 NC_007354.1 PpiC-type peptidyl-prolyl cis-trans isomerase 502775 3618184 Ecaj_0334 Ehrlichia canis str. Jake PpiC-type peptidyl-prolyl cis-trans isomerase YP_302975.1 500883 R 269484 CDS YP_302976.1 73666960 3618185 complement(502999..503577) 1 NC_007354.1 peptidase M22, glycoprotease 503577 3618185 Ecaj_0335 Ehrlichia canis str. Jake peptidase M22, glycoprotease YP_302976.1 502999 R 269484 CDS YP_302977.1 73666961 3618187 504476..505381 1 NC_007354.1 tRNA pseudouridine synthase B 505381 3618187 Ecaj_0336 Ehrlichia canis str. Jake tRNA pseudouridine synthase B YP_302977.1 504476 D 269484 CDS YP_302978.1 73666962 3618188 505384..505665 1 NC_007354.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 505665 rpsO 3618188 rpsO Ehrlichia canis str. Jake 30S ribosomal protein S15 YP_302978.1 505384 D 269484 CDS YP_302979.1 73666963 3618189 505704..508094 1 NC_007354.1 polynucleotide phosphorylase/polyadenylase 508094 3618189 Ecaj_0338 Ehrlichia canis str. Jake polynucleotide phosphorylase/polyadenylase YP_302979.1 505704 D 269484 CDS YP_302980.1 73666964 3618190 508121..508912 1 NC_007354.1 hypothetical protein 508912 3618190 Ecaj_0339 Ehrlichia canis str. Jake hypothetical protein YP_302980.1 508121 D 269484 CDS YP_302981.1 73666965 3618191 508942..510738 1 NC_007354.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 510738 3618191 Ecaj_0340 Ehrlichia canis str. Jake GTP-binding protein LepA YP_302981.1 508942 D 269484 CDS YP_302982.1 73666966 3618192 511037..511609 1 NC_007354.1 hypothetical protein 511609 3618192 Ecaj_0341 Ehrlichia canis str. Jake hypothetical protein YP_302982.1 511037 D 269484 CDS YP_302983.1 73666967 3618193 512383..513036 1 NC_007354.1 hypothetical protein 513036 3618193 Ecaj_0342 Ehrlichia canis str. Jake hypothetical protein YP_302983.1 512383 D 269484 CDS YP_302984.1 73666968 3618194 513217..513762 1 NC_007354.1 hypothetical protein 513762 3618194 Ecaj_0343 Ehrlichia canis str. Jake hypothetical protein YP_302984.1 513217 D 269484 CDS YP_302985.1 73666969 3618195 514283..516562 1 NC_007354.1 hypothetical protein 516562 3618195 Ecaj_0344 Ehrlichia canis str. Jake hypothetical protein YP_302985.1 514283 D 269484 CDS YP_302986.1 73666970 3618196 516944..518839 1 NC_007354.1 hypothetical protein 518839 3618196 Ecaj_0345 Ehrlichia canis str. Jake hypothetical protein YP_302986.1 516944 D 269484 CDS YP_302987.1 73666971 3618197 518954..520510 1 NC_007354.1 hypothetical protein 520510 3618197 Ecaj_0346 Ehrlichia canis str. Jake hypothetical protein YP_302987.1 518954 D 269484 CDS YP_302988.1 73666972 3618198 521551..522615 1 NC_007354.1 hypothetical protein 522615 3618198 Ecaj_0347 Ehrlichia canis str. Jake hypothetical protein YP_302988.1 521551 D 269484 CDS YP_302989.1 73666973 3618199 522890..524497 1 NC_007354.1 hypothetical protein 524497 3618199 Ecaj_0348 Ehrlichia canis str. Jake hypothetical protein YP_302989.1 522890 D 269484 CDS YP_302990.1 73666974 3618200 524544..524870 1 NC_007354.1 hypothetical protein 524870 3618200 Ecaj_0349 Ehrlichia canis str. Jake hypothetical protein YP_302990.1 524544 D 269484 CDS YP_302991.1 73666975 3617786 complement(525474..526481) 1 NC_007354.1 peptide chain release factor 2 526481 3617786 Ecaj_0350 Ehrlichia canis str. Jake peptide chain release factor 2 YP_302991.1 525474 R 269484 CDS YP_302992.1 73666976 3617787 complement(526886..527632) 1 NC_007354.1 hypothetical protein 527632 3617787 Ecaj_0351 Ehrlichia canis str. Jake hypothetical protein YP_302992.1 526886 R 269484 CDS YP_302993.1 73666977 3617788 complement(527647..529149) 1 NC_007354.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 529149 gatA 3617788 gatA Ehrlichia canis str. Jake aspartyl/glutamyl-tRNA amidotransferase subunit A YP_302993.1 527647 R 269484 CDS YP_302994.1 73666978 3617789 529505..530809 1 NC_007354.1 folylpolyglutamate synthetase 530809 3617789 Ecaj_0353 Ehrlichia canis str. Jake folylpolyglutamate synthetase YP_302994.1 529505 D 269484 CDS YP_302995.1 73666979 3617790 531265..532161 1 NC_007354.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 532161 hemC 3617790 hemC Ehrlichia canis str. Jake porphobilinogen deaminase YP_302995.1 531265 D 269484 CDS YP_302996.1 73666980 3617791 532987..533613 1 NC_007354.1 hypothetical protein 533613 3617791 Ecaj_0355 Ehrlichia canis str. Jake hypothetical protein YP_302996.1 532987 D 269484 CDS YP_302997.1 73666981 3617792 533583..533840 1 NC_007354.1 hypothetical protein 533840 3617792 Ecaj_0356 Ehrlichia canis str. Jake hypothetical protein YP_302997.1 533583 D 269484 CDS YP_302998.1 73666982 3617793 534865..535542 1 NC_007354.1 hypothetical protein 535542 3617793 Ecaj_0357 Ehrlichia canis str. Jake hypothetical protein YP_302998.1 534865 D 269484 CDS YP_302999.1 73666983 3617794 537117..537857 1 NC_007354.1 hypothetical protein 537857 3617794 Ecaj_0358 Ehrlichia canis str. Jake hypothetical protein YP_302999.1 537117 D 269484 CDS YP_303000.1 73666984 3617795 538216..540060 1 NC_007354.1 GTP-binding protein TypA 540060 3617795 Ecaj_0359 Ehrlichia canis str. Jake GTP-binding protein TypA YP_303000.1 538216 D 269484 CDS YP_303001.1 73666985 3617796 540232..540582 1 NC_007354.1 hypothetical protein 540582 3617796 Ecaj_0360 Ehrlichia canis str. Jake hypothetical protein YP_303001.1 540232 D 269484 CDS YP_303002.1 73666986 3617797 complement(540615..541118) 1 NC_007354.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 541118 3617797 Ecaj_0361 Ehrlichia canis str. Jake NADH dehydrogenase subunit I YP_303002.1 540615 R 269484 CDS YP_303003.1 73666987 3617798 complement(541126..541836) 1 NC_007354.1 signal peptidase I 541836 3617798 Ecaj_0362 Ehrlichia canis str. Jake signal peptidase I YP_303003.1 541126 R 269484 CDS YP_303004.1 73666988 3617799 complement(541851..542306) 1 NC_007354.1 HesB/YadR/YfhF 542306 3617799 Ecaj_0363 Ehrlichia canis str. Jake HesB/YadR/YfhF YP_303004.1 541851 R 269484 CDS YP_303005.1 73666989 3617800 542377..543570 1 NC_007354.1 deoxyguanosinetriphosphate triphosphohydrolase 543570 3617800 Ecaj_0364 Ehrlichia canis str. Jake deoxyguanosinetriphosphate triphosphohydrolase YP_303005.1 542377 D 269484 CDS YP_303006.1 73666990 3617801 543799..548064 1 NC_007354.1 gp200 548064 3617801 Ecaj_0365 Ehrlichia canis str. Jake gp200 YP_303006.1 543799 D 269484 CDS YP_303007.1 73666991 3617803 548982..549809 1 NC_007354.1 hypothetical protein 549809 3617803 Ecaj_0366 Ehrlichia canis str. Jake hypothetical protein YP_303007.1 548982 D 269484 CDS YP_303008.1 73666992 3617804 complement(550924..552105) 1 NC_007354.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 552105 3617804 Ecaj_0367 Ehrlichia canis str. Jake argininosuccinate synthase YP_303008.1 550924 R 269484 CDS YP_303009.1 73666993 3617824 552258..552938 1 NC_007354.1 hypothetical protein 552938 3617824 Ecaj_0368 Ehrlichia canis str. Jake hypothetical protein YP_303009.1 552258 D 269484 CDS YP_303010.1 73666994 3617825 553246..553938 1 NC_007354.1 hypothetical protein 553938 3617825 Ecaj_0369 Ehrlichia canis str. Jake hypothetical protein YP_303010.1 553246 D 269484 CDS YP_303011.1 73666995 3617826 554190..555461 1 NC_007354.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 555461 argJ 3617826 argJ Ehrlichia canis str. Jake bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_303011.1 554190 D 269484 CDS YP_303012.1 73666996 3617827 555483..556322 1 NC_007354.1 exodeoxyribonuclease III 556322 3617827 Ecaj_0371 Ehrlichia canis str. Jake exodeoxyribonuclease III YP_303012.1 555483 D 269484 CDS YP_303013.1 73666997 3617828 complement(556836..557612) 1 NC_007354.1 hypothetical protein 557612 3617828 Ecaj_0372 Ehrlichia canis str. Jake hypothetical protein YP_303013.1 556836 R 269484 CDS YP_303014.1 73666998 3617560 complement(557918..558715) 1 NC_007354.1 hypothetical protein 558715 3617560 Ecaj_0373 Ehrlichia canis str. Jake hypothetical protein YP_303014.1 557918 R 269484 CDS YP_303015.1 73666999 3617561 complement(558729..559463) 1 NC_007354.1 3-oxoacyl-ACP reductase 559463 3617561 Ecaj_0374 Ehrlichia canis str. Jake 3-oxoacyl-ACP reductase YP_303015.1 558729 R 269484 CDS YP_303016.1 73667000 3617562 560097..563246 1 NC_007354.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 563246 3617562 Ecaj_0375 Ehrlichia canis str. Jake bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_303016.1 560097 D 269484 CDS YP_303017.1 73667001 3617563 563778..565064 1 NC_007354.1 aminotransferase 565064 3617563 Ecaj_0376 Ehrlichia canis str. Jake aminotransferase YP_303017.1 563778 D 269484 CDS YP_303018.1 73667002 3617564 complement(566033..567442) 1 NC_007354.1 phage protein 567442 3617564 Ecaj_0377 Ehrlichia canis str. Jake phage protein YP_303018.1 566033 R 269484 CDS YP_303019.1 73667003 3617565 complement(567561..568190) 1 NC_007354.1 hypothetical protein 568190 3617565 Ecaj_0378 Ehrlichia canis str. Jake hypothetical protein YP_303019.1 567561 R 269484 CDS YP_303020.1 73667004 3617566 complement(568332..568880) 1 NC_007354.1 hypothetical protein 568880 3617566 Ecaj_0379 Ehrlichia canis str. Jake hypothetical protein YP_303020.1 568332 R 269484 CDS YP_303021.1 73667005 3617567 complement(568954..569343) 1 NC_007354.1 hypothetical protein 569343 3617567 Ecaj_0380 Ehrlichia canis str. Jake hypothetical protein YP_303021.1 568954 R 269484 CDS YP_303022.1 73667006 3617568 complement(569321..569725) 1 NC_007354.1 hypothetical protein 569725 3617568 Ecaj_0382 Ehrlichia canis str. Jake hypothetical protein YP_303022.1 569321 R 269484 CDS YP_303023.1 73667007 3617569 complement(569722..570276) 1 NC_007354.1 phage protein 570276 3617569 Ecaj_0381 Ehrlichia canis str. Jake phage protein YP_303023.1 569722 R 269484 CDS YP_303024.1 73667008 3617570 complement(570325..570675) 1 NC_007354.1 hypothetical protein 570675 3617570 Ecaj_0383 Ehrlichia canis str. Jake hypothetical protein YP_303024.1 570325 R 269484 CDS YP_303025.1 73667009 3617597 571207..571335 1 NC_007354.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 571335 rpmJ 3617597 rpmJ Ehrlichia canis str. Jake 50S ribosomal protein L36 YP_303025.1 571207 D 269484 CDS YP_303026.1 73667010 3617598 complement(571776..572678) 1 NC_007354.1 sigma-70 region 2:sigma-70 region 4 572678 3617598 Ecaj_0385 Ehrlichia canis str. Jake sigma-70 region 2:sigma-70 region 4 YP_303026.1 571776 R 269484 CDS YP_303027.1 73667011 3617599 572779..573372 1 NC_007354.1 sigma 54 modulation protein/ribosomal protein S30EA 573372 3617599 Ecaj_0386 Ehrlichia canis str. Jake sigma 54 modulation protein/ribosomal protein S30EA YP_303027.1 572779 D 269484 CDS YP_303028.1 73667012 3617600 573594..586331 1 NC_007354.1 ankyrin 586331 3617600 Ecaj_0387 Ehrlichia canis str. Jake ankyrin YP_303028.1 573594 D 269484 CDS YP_303029.1 73667013 3617601 586429..587274 1 NC_007354.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 587274 3617601 Ecaj_0388 Ehrlichia canis str. Jake F0F1 ATP synthase subunit gamma YP_303029.1 586429 D 269484 CDS YP_303030.1 73667014 3617602 587287..587859 1 NC_007354.1 GTP cyclohydrolase 587859 3617602 Ecaj_0389 Ehrlichia canis str. Jake GTP cyclohydrolase YP_303030.1 587287 D 269484 CDS YP_303031.1 73667015 3617603 587872..589206 1 NC_007354.1 microcin-processing peptidase 1 589206 3617603 Ecaj_0390 Ehrlichia canis str. Jake microcin-processing peptidase 1 YP_303031.1 587872 D 269484 CDS YP_303032.1 73667016 3617604 complement(589804..590820) 1 NC_007354.1 FAD-dependent pyridine nucleotide-disulfide oxidoreductase 590820 3617604 Ecaj_0391 Ehrlichia canis str. Jake FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_303032.1 589804 R 269484 CDS YP_303033.1 73667017 3617605 complement(591138..591926) 1 NC_007354.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 591926 ksgA 3617605 ksgA Ehrlichia canis str. Jake dimethyladenosine transferase YP_303033.1 591138 R 269484 CDS YP_303034.1 73667018 3617607 592096..592863 1 NC_007354.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 592863 3617607 Ecaj_0393 Ehrlichia canis str. Jake triosephosphate isomerase YP_303034.1 592096 D 269484 CDS YP_303035.1 73667019 3617608 592863..593843 1 NC_007354.1 putative immunogenic protein 593843 3617608 Ecaj_0394 Ehrlichia canis str. Jake putative immunogenic protein YP_303035.1 592863 D 269484 CDS YP_303036.1 73667020 3617609 593857..594909 1 NC_007354.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 594909 3617609 Ecaj_0395 Ehrlichia canis str. Jake putative DNA-binding/iron metalloprotein/AP endonuclease YP_303036.1 593857 D 269484 CDS YP_303037.1 73667021 3617610 complement(595982..596572) 1 NC_007354.1 hypothetical protein 596572 3617610 Ecaj_0396 Ehrlichia canis str. Jake hypothetical protein YP_303037.1 595982 R 269484 CDS YP_303038.1 73667022 3617611 596767..597123 1 NC_007354.1 dihydroneopterin aldolase 597123 3617611 Ecaj_0397 Ehrlichia canis str. Jake dihydroneopterin aldolase YP_303038.1 596767 D 269484 CDS YP_303039.1 73667023 3617612 597186..598127 1 NC_007354.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 598127 3617612 Ecaj_0398 Ehrlichia canis str. Jake malate dehydrogenase YP_303039.1 597186 D 269484 CDS YP_303040.1 73667024 3617613 598334..599293 1 NC_007354.1 hypothetical protein 599293 3617613 Ecaj_0399 Ehrlichia canis str. Jake hypothetical protein YP_303040.1 598334 D 269484 CDS YP_303041.1 73667025 3617614 complement(599789..600019) 1 NC_007354.1 hypothetical protein 600019 3617614 Ecaj_0400 Ehrlichia canis str. Jake hypothetical protein YP_303041.1 599789 R 269484 CDS YP_303042.1 73667026 3618382 600164..600613 1 NC_007354.1 ribose/galactose isomerase 600613 3618382 Ecaj_0401 Ehrlichia canis str. Jake ribose/galactose isomerase YP_303042.1 600164 D 269484 CDS YP_303043.1 73667027 3618383 600610..601329 1 NC_007354.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 601329 3618383 Ecaj_0402 Ehrlichia canis str. Jake 3-demethylubiquinone-9 3-methyltransferase YP_303043.1 600610 D 269484 CDS YP_303044.1 73667028 3618384 complement(601469..601867) 1 NC_007354.1 cytochrome c-type biogenesis protein CcmH 601867 3618384 Ecaj_0403 Ehrlichia canis str. Jake cytochrome c-type biogenesis protein CcmH YP_303044.1 601469 R 269484 CDS YP_303045.1 73667029 3618385 complement(601851..602924) 1 NC_007354.1 hypothetical protein 602924 3618385 Ecaj_0404 Ehrlichia canis str. Jake hypothetical protein YP_303045.1 601851 R 269484 CDS YP_303046.1 73667030 3618386 complement(602939..603289) 1 NC_007354.1 ferredoxin 603289 3618386 Ecaj_0405 Ehrlichia canis str. Jake ferredoxin YP_303046.1 602939 R 269484 CDS YP_303047.1 73667031 3618387 complement(603317..605173) 1 NC_007354.1 heat shock protein Hsp70 605173 3618387 Ecaj_0406 Ehrlichia canis str. Jake heat shock protein Hsp70 YP_303047.1 603317 R 269484 CDS YP_303048.1 73667032 3618388 complement(605173..605610) 1 NC_007354.1 heat shock protein DnaJ, N-terminal 605610 3618388 Ecaj_0407 Ehrlichia canis str. Jake heat shock protein DnaJ, N-terminal YP_303048.1 605173 R 269484 CDS YP_303049.1 73667033 3618389 complement(605603..606028) 1 NC_007354.1 HesB/YadR/YfhF 606028 3618389 Ecaj_0408 Ehrlichia canis str. Jake HesB/YadR/YfhF YP_303049.1 605603 R 269484 CDS YP_303050.1 73667034 3618390 complement(606059..606475) 1 NC_007354.1 scaffold protein 606475 3618390 Ecaj_0409 Ehrlichia canis str. Jake scaffold protein YP_303050.1 606059 R 269484 CDS YP_303051.1 73667035 3618391 complement(606511..607779) 1 NC_007354.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 607779 3618391 Ecaj_0410 Ehrlichia canis str. Jake cysteine desulfurase YP_303051.1 606511 R 269484 CDS YP_303052.1 73667036 3618539 complement(607810..609411) 1 NC_007354.1 BadM/Rrf2 family transcriptional regulator 609411 3618539 Ecaj_0411 Ehrlichia canis str. Jake BadM/Rrf2 family transcriptional regulator YP_303052.1 607810 R 269484 CDS YP_303053.1 73667037 3618485 609733..610458 1 NC_007354.1 hypothetical protein 610458 3618485 Ecaj_0412 Ehrlichia canis str. Jake hypothetical protein YP_303053.1 609733 D 269484 CDS YP_303054.1 73667038 3618486 610782..612317 1 NC_007354.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 612317 lysK 3618486 lysK Ehrlichia canis str. Jake lysyl-tRNA synthetase YP_303054.1 610782 D 269484 CDS YP_303055.1 73667039 3618487 612435..612872 1 NC_007354.1 hypothetical protein 612872 3618487 Ecaj_0414 Ehrlichia canis str. Jake hypothetical protein YP_303055.1 612435 D 269484 CDS YP_303056.1 73667040 3618488 615106..615708 1 NC_007354.1 hypothetical protein 615708 3618488 Ecaj_0415 Ehrlichia canis str. Jake hypothetical protein YP_303056.1 615106 D 269484 CDS YP_303057.1 73667041 3618489 617223..617747 1 NC_007354.1 hypothetical protein 617747 3618489 Ecaj_0416 Ehrlichia canis str. Jake hypothetical protein YP_303057.1 617223 D 269484 CDS YP_303058.1 73667042 3618490 complement(618487..620883) 1 NC_007354.1 DNA gyrase subunit B 620883 3618490 Ecaj_0417 Ehrlichia canis str. Jake DNA gyrase subunit B YP_303058.1 618487 R 269484 CDS YP_303059.1 73667043 3618491 621197..622114 1 NC_007354.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 622114 pyrB 3618491 pyrB Ehrlichia canis str. Jake aspartate carbamoyltransferase catalytic subunit YP_303059.1 621197 D 269484 CDS YP_303060.1 73667044 3617557 622104..622841 1 NC_007354.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 622841 truA 3617557 truA Ehrlichia canis str. Jake tRNA pseudouridine synthase A YP_303060.1 622104 D 269484 CDS YP_303061.1 73667045 3617767 623809..624027 1 NC_007354.1 hypothetical protein 624027 3617767 Ecaj_0420 Ehrlichia canis str. Jake hypothetical protein YP_303061.1 623809 D 269484 CDS YP_303062.1 73667046 3617768 624037..626088 1 NC_007354.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 626088 3617768 Ecaj_0421 Ehrlichia canis str. Jake NADH dehydrogenase subunit G YP_303062.1 624037 D 269484 CDS YP_303063.1 73667047 3617769 626095..627204 1 NC_007354.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 627204 3617769 Ecaj_0422 Ehrlichia canis str. Jake NADH dehydrogenase subunit H YP_303063.1 626095 D 269484 CDS YP_303064.1 73667048 3617770 627570..628343 1 NC_007354.1 hypothetical protein 628343 3617770 Ecaj_0423 Ehrlichia canis str. Jake hypothetical protein YP_303064.1 627570 D 269484 CDS YP_303065.1 73667049 3617771 628987..629226 1 NC_007354.1 hypothetical protein 629226 3617771 Ecaj_0425 Ehrlichia canis str. Jake hypothetical protein YP_303065.1 628987 D 269484 CDS YP_303066.1 73667050 3617772 630695..631876 1 NC_007354.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 631876 3617772 Ecaj_0426 Ehrlichia canis str. Jake NADH dehydrogenase subunit D YP_303066.1 630695 D 269484 CDS YP_303067.1 73667051 3617773 631883..632425 1 NC_007354.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 632425 3617773 Ecaj_0427 Ehrlichia canis str. Jake NADH dehydrogenase subunit E YP_303067.1 631883 D 269484 CDS YP_303068.1 73667052 3617774 complement(634633..635505) 1 NC_007354.1 hypothetical protein 635505 3617774 Ecaj_0428 Ehrlichia canis str. Jake hypothetical protein YP_303068.1 634633 R 269484 CDS YP_303069.1 73667053 3617775 complement(635651..636406) 1 NC_007354.1 hypothetical protein 636406 3617775 Ecaj_0429 Ehrlichia canis str. Jake hypothetical protein YP_303069.1 635651 R 269484 CDS YP_303070.1 73667054 3617776 complement(636510..637061) 1 NC_007354.1 hypothetical protein 637061 3617776 Ecaj_0430 Ehrlichia canis str. Jake hypothetical protein YP_303070.1 636510 R 269484 CDS YP_303071.1 73667055 3617777 complement(637246..638556) 1 NC_007354.1 hypothetical protein 638556 3617777 Ecaj_0431 Ehrlichia canis str. Jake hypothetical protein YP_303071.1 637246 R 269484 CDS YP_303072.1 73667056 3617778 complement(638995..640404) 1 NC_007354.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 640404 gltX 3617778 gltX Ehrlichia canis str. Jake glutamyl-tRNA synthetase YP_303072.1 638995 R 269484 CDS YP_303073.1 73667057 3617780 641516..641896 1 NC_007354.1 hypothetical protein 641896 3617780 Ecaj_0433 Ehrlichia canis str. Jake hypothetical protein YP_303073.1 641516 D 269484 CDS YP_303074.1 73667058 3617781 642521..643192 1 NC_007354.1 hypothetical protein 643192 3617781 Ecaj_0434 Ehrlichia canis str. Jake hypothetical protein YP_303074.1 642521 D 269484 CDS YP_303075.1 73667059 3617782 643546..644133 1 NC_007354.1 hypothetical protein 644133 3617782 Ecaj_0435 Ehrlichia canis str. Jake hypothetical protein YP_303075.1 643546 D 269484 CDS YP_303076.1 73667060 3617783 644426..645013 1 NC_007354.1 hypothetical protein 645013 3617783 Ecaj_0436 Ehrlichia canis str. Jake hypothetical protein YP_303076.1 644426 D 269484 CDS YP_303077.1 73667061 3617784 645165..646694 1 NC_007354.1 carboxyl transferase 646694 3617784 Ecaj_0437 Ehrlichia canis str. Jake carboxyl transferase YP_303077.1 645165 D 269484 CDS YP_303078.1 73667062 3617785 complement(646967..647569) 1 NC_007354.1 hypothetical protein 647569 3617785 Ecaj_0438 Ehrlichia canis str. Jake hypothetical protein YP_303078.1 646967 R 269484 CDS YP_303079.1 73667063 3618045 648564..649085 1 NC_007354.1 class I peptide chain release factor domain-containing protein 649085 3618045 Ecaj_0440 Ehrlichia canis str. Jake class I peptide chain release factor domain-containing protein YP_303079.1 648564 D 269484 CDS YP_303080.1 73667064 3618047 complement(649672..650751) 1 NC_007354.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 650751 prfA 3618047 prfA Ehrlichia canis str. Jake peptide chain release factor 1 YP_303080.1 649672 R 269484 CDS YP_303081.1 73667065 3618048 650919..651521 1 NC_007354.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 651521 engB 3618048 engB Ehrlichia canis str. Jake ribosome biogenesis GTP-binding protein YsxC YP_303081.1 650919 D 269484 CDS YP_303082.1 73667066 3618049 651493..652464 1 NC_007354.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 652464 3618049 Ecaj_0444 Ehrlichia canis str. Jake acetylglutamate kinase YP_303082.1 651493 D 269484 CDS YP_303083.1 73667067 3618050 652756..653904 1 NC_007354.1 hypothetical protein 653904 3618050 Ecaj_0445 Ehrlichia canis str. Jake hypothetical protein YP_303083.1 652756 D 269484 CDS YP_303084.1 73667068 3618051 654126..654974 1 NC_007354.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 654974 3618051 Ecaj_0446 Ehrlichia canis str. Jake coproporphyrinogen III oxidase YP_303084.1 654126 D 269484 CDS YP_303085.1 73667069 3618052 complement(655678..656991) 1 NC_007354.1 hypothetical protein 656991 3618052 Ecaj_0447 Ehrlichia canis str. Jake hypothetical protein YP_303085.1 655678 R 269484 CDS YP_303086.1 73667070 3618053 complement(657839..658522) 1 NC_007354.1 type IV secretory pathway, VirB3-like 658522 3618053 Ecaj_0448 Ehrlichia canis str. Jake type IV secretory pathway, VirB3-like YP_303086.1 657839 R 269484 CDS YP_303087.1 73667071 3618054 658740..660020 1 NC_007354.1 Sodium:dicarboxylate symporter 660020 3618054 Ecaj_0449 Ehrlichia canis str. Jake Sodium:dicarboxylate symporter YP_303087.1 658740 D 269484 CDS YP_303088.1 73667072 3618055 complement(660601..661593) 1 NC_007354.1 hypothetical protein 661593 3618055 Ecaj_0450 Ehrlichia canis str. Jake hypothetical protein YP_303088.1 660601 R 269484 CDS YP_303089.1 73667073 3618059 complement(662546..663817) 1 NC_007354.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 663817 3618059 Ecaj_0454 Ehrlichia canis str. Jake seryl-tRNA synthetase YP_303089.1 662546 R 269484 CDS YP_303090.1 73667074 3618060 complement(663898..665121) 1 NC_007354.1 putative 3-hydroxyacyl-CoA dehydrogenase 665121 3618060 Ecaj_0455 Ehrlichia canis str. Jake putative 3-hydroxyacyl-CoA dehydrogenase YP_303090.1 663898 R 269484 CDS YP_303091.1 73667075 3618061 complement(665203..665664) 1 NC_007354.1 hypothetical protein 665664 3618061 Ecaj_0456 Ehrlichia canis str. Jake hypothetical protein YP_303091.1 665203 R 269484 CDS YP_303092.1 73667076 3618062 665786..666688 1 NC_007354.1 tRNA isopentenyl transferase 666688 3618062 Ecaj_0457 Ehrlichia canis str. Jake tRNA isopentenyl transferase YP_303092.1 665786 D 269484 CDS YP_303093.1 73667077 3618025 complement(667238..668608) 1 NC_007354.1 divalent cation transporter 668608 3618025 Ecaj_0458 Ehrlichia canis str. Jake divalent cation transporter YP_303093.1 667238 R 269484 CDS YP_303094.1 73667078 3618027 669000..670523 1 NC_007354.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 670523 3618027 Ecaj_0459 Ehrlichia canis str. Jake F0F1 ATP synthase subunit beta YP_303094.1 669000 D 269484 CDS YP_303095.1 73667079 3618028 670523..670909 1 NC_007354.1 H+-transporting two-sector ATPase, delta/epsilon subunit 670909 3618028 Ecaj_0460 Ehrlichia canis str. Jake H+-transporting two-sector ATPase, delta/epsilon subunit YP_303095.1 670523 D 269484 CDS YP_303096.1 73667080 3618029 670916..671578 1 NC_007354.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 671578 3618029 Ecaj_0461 Ehrlichia canis str. Jake putative translaldolase YP_303096.1 670916 D 269484 CDS YP_303097.1 73667081 3618030 671883..672164 1 NC_007354.1 hypothetical protein 672164 3618030 Ecaj_0462 Ehrlichia canis str. Jake hypothetical protein YP_303097.1 671883 D 269484 CDS YP_303098.1 73667082 3618031 complement(673070..677056) 1 NC_007354.1 hypothetical protein 677056 3618031 Ecaj_0463 Ehrlichia canis str. Jake hypothetical protein YP_303098.1 673070 R 269484 CDS YP_303099.1 73667083 3618032 complement(677230..679509) 1 NC_007354.1 ATP-dependent Clp protease 679509 3618032 Ecaj_0464 Ehrlichia canis str. Jake ATP-dependent Clp protease YP_303099.1 677230 R 269484 CDS YP_303100.1 73667084 3618033 679680..680363 1 NC_007354.1 TerC family integral membrane protein 680363 3618033 Ecaj_0465 Ehrlichia canis str. Jake TerC family integral membrane protein YP_303100.1 679680 D 269484 CDS YP_303101.1 73667085 3618034 complement(680389..680736) 1 NC_007354.1 ribosome-binding factor A 680736 3618034 Ecaj_0466 Ehrlichia canis str. Jake ribosome-binding factor A YP_303101.1 680389 R 269484 CDS YP_303102.1 73667086 3618035 complement(680733..683279) 1 NC_007354.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 683279 infB 3618035 infB Ehrlichia canis str. Jake translation initiation factor IF-2 YP_303102.1 680733 R 269484 CDS YP_303103.1 73667087 3618036 complement(683303..684856) 1 NC_007354.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 684856 nusA 3618036 nusA Ehrlichia canis str. Jake transcription elongation factor NusA YP_303103.1 683303 R 269484 CDS YP_303104.1 73667088 3618037 complement(685003..688119) 1 NC_007354.1 acriflavin resistance protein 688119 3618037 Ecaj_0469 Ehrlichia canis str. Jake acriflavin resistance protein YP_303104.1 685003 R 269484 CDS YP_303105.1 73667089 3618038 complement(688203..688955) 1 NC_007354.1 twin-arginine translocating C- subunit 688955 3618038 Ecaj_0470 Ehrlichia canis str. Jake twin-arginine translocating C- subunit YP_303105.1 688203 R 269484 CDS YP_303106.1 73667090 3618039 complement(688979..690247) 1 NC_007354.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 690247 ispG 3618039 ispG Ehrlichia canis str. Jake 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_303106.1 688979 R 269484 CDS YP_303107.1 73667091 3618040 complement(690336..692261) 1 NC_007354.1 hypothetical protein 692261 3618040 Ecaj_0472 Ehrlichia canis str. Jake hypothetical protein YP_303107.1 690336 R 269484 CDS YP_303108.1 73667092 3618041 complement(692522..693685) 1 NC_007354.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 693685 3618041 Ecaj_0473 Ehrlichia canis str. Jake 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_303108.1 692522 R 269484 CDS YP_303109.1 73667093 3618042 complement(693737..695161) 1 NC_007354.1 proton-translocating NADH-quinoneoxidoreductase, chain N 695161 3618042 Ecaj_0474 Ehrlichia canis str. Jake proton-translocating NADH-quinoneoxidoreductase, chain N YP_303109.1 693737 R 269484 CDS YP_303110.1 73667094 3618043 complement(695179..696636) 1 NC_007354.1 proton-translocating NADH-quinoneoxidoreductase, chain M 696636 3618043 Ecaj_0475 Ehrlichia canis str. Jake proton-translocating NADH-quinoneoxidoreductase, chain M YP_303110.1 695179 R 269484 CDS YP_303111.1 73667095 3618275 complement(696642..698507) 1 NC_007354.1 NADH-plastoquinone oxidoreductase, chain 5 698507 3618275 Ecaj_0476 Ehrlichia canis str. Jake NADH-plastoquinone oxidoreductase, chain 5 YP_303111.1 696642 R 269484 CDS YP_303112.1 73667096 3618276 complement(698591..698917) 1 NC_007354.1 NADH-ubiquinone oxidoreductase, chain 4L 698917 3618276 Ecaj_0477 Ehrlichia canis str. Jake NADH-ubiquinone oxidoreductase, chain 4L YP_303112.1 698591 R 269484 CDS YP_303113.1 73667097 3618277 complement(698901..699503) 1 NC_007354.1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 699503 3618277 Ecaj_0478 Ehrlichia canis str. Jake NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_303113.1 698901 R 269484 CDS YP_303114.1 73667098 3618278 complement(699863..700444) 1 NC_007354.1 hypothetical protein 700444 3618278 Ecaj_0479 Ehrlichia canis str. Jake hypothetical protein YP_303114.1 699863 R 269484 CDS YP_303115.1 73667099 3617830 complement(700570..701187) 1 NC_007354.1 hypothetical protein 701187 3617830 Ecaj_0480 Ehrlichia canis str. Jake hypothetical protein YP_303115.1 700570 R 269484 CDS YP_303116.1 73667100 3618372 complement(703345..703854) 1 NC_007354.1 hypothetical protein 703854 3618372 Ecaj_0481 Ehrlichia canis str. Jake hypothetical protein YP_303116.1 703345 R 269484 CDS YP_303117.1 73667101 3617895 complement(704712..704990) 1 NC_007354.1 hypothetical protein 704990 3617895 Ecaj_0482 Ehrlichia canis str. Jake hypothetical protein YP_303117.1 704712 R 269484 CDS YP_303118.1 73667102 3618495 complement(705049..705318) 1 NC_007354.1 hypothetical protein 705318 3618495 Ecaj_0483 Ehrlichia canis str. Jake hypothetical protein YP_303118.1 705049 R 269484 CDS YP_303119.1 73667103 3618496 complement(706214..706810) 1 NC_007354.1 hypothetical protein 706810 3618496 Ecaj_0484 Ehrlichia canis str. Jake hypothetical protein YP_303119.1 706214 R 269484 CDS YP_303120.1 73667104 3618497 complement(708421..709023) 1 NC_007354.1 hypothetical protein 709023 3618497 Ecaj_0485 Ehrlichia canis str. Jake hypothetical protein YP_303120.1 708421 R 269484 CDS YP_303121.1 73667105 3618479 complement(709313..710596) 1 NC_007354.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 710596 3618479 Ecaj_0486 Ehrlichia canis str. Jake NADH dehydrogenase I subunit F YP_303121.1 709313 R 269484 CDS YP_303122.1 73667106 3618481 complement(710834..711100) 1 NC_007354.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 711100 rpmA 3618481 rpmA Ehrlichia canis str. Jake 50S ribosomal protein L27 YP_303122.1 710834 R 269484 CDS YP_303123.1 73667107 3618482 complement(711106..711414) 1 NC_007354.1 50S ribosomal protein L21 711414 rplU 3618482 rplU Ehrlichia canis str. Jake 50S ribosomal protein L21 YP_303123.1 711106 R 269484 CDS YP_303124.1 73667108 3618483 711604..712869 1 NC_007354.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 712869 eno 3618483 eno Ehrlichia canis str. Jake phosphopyruvate hydratase YP_303124.1 711604 D 269484 CDS YP_303125.1 73667109 3618484 712866..713888 1 NC_007354.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 713888 obgE 3618484 obgE Ehrlichia canis str. Jake GTPase ObgE YP_303125.1 712866 D 269484 CDS YP_303126.1 73667110 3618371 complement(715081..715974) 1 NC_007354.1 S-adenosyl-methyltransferase MraW 715974 mraW 3618371 mraW Ehrlichia canis str. Jake S-adenosyl-methyltransferase MraW YP_303126.1 715081 R 269484 CDS YP_303127.1 73667111 3618498 complement(716262..716783) 1 NC_007354.1 5-formyltetrahydrofolate cyclo-ligase 716783 3618498 Ecaj_0492 Ehrlichia canis str. Jake 5-formyltetrahydrofolate cyclo-ligase YP_303127.1 716262 R 269484 CDS YP_303128.1 73667112 3618201 complement(716788..717507) 1 NC_007354.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 717507 3618201 Ecaj_0493 Ehrlichia canis str. Jake 16S ribosomal RNA methyltransferase RsmE YP_303128.1 716788 R 269484 CDS YP_303129.1 73667113 3618202 complement(717523..717966) 1 NC_007354.1 alkyl hydroperoxide reductase/thiol specific antioxidant/ Mal allergen 717966 3618202 Ecaj_0494 Ehrlichia canis str. Jake alkyl hydroperoxide reductase/thiol specific antioxidant/ Mal allergen YP_303129.1 717523 R 269484 CDS YP_303130.2 161702947 3618203 718108..721431 1 NC_007354.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 721431 ileS 3618203 ileS Ehrlichia canis str. Jake isoleucyl-tRNA synthetase YP_303130.2 718108 D 269484 CDS YP_303131.1 73667115 3618204 722561..722857 1 NC_007354.1 hypothetical protein 722857 3618204 Ecaj_0496 Ehrlichia canis str. Jake hypothetical protein YP_303131.1 722561 D 269484 CDS YP_303132.1 73667116 3618507 complement(723565..725295) 1 NC_007354.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 725295 argS 3618507 argS Ehrlichia canis str. Jake arginyl-tRNA synthetase YP_303132.1 723565 R 269484 CDS YP_303133.2 161702946 3617996 725639..726373 1 NC_007354.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 726373 recO 3617996 recO Ehrlichia canis str. Jake DNA repair protein RecO YP_303133.2 725639 D 269484 CDS YP_303134.1 73667118 3617997 726573..727130 1 NC_007354.1 hypothetical protein 727130 3617997 Ecaj_0500 Ehrlichia canis str. Jake hypothetical protein YP_303134.1 726573 D 269484 CDS YP_303135.1 73667119 3617999 728080..728595 1 NC_007354.1 ribosomal RNA methyl transferase RrmJ/FtsJ 728595 3617999 Ecaj_0501 Ehrlichia canis str. Jake ribosomal RNA methyl transferase RrmJ/FtsJ YP_303135.1 728080 D 269484 CDS YP_303136.1 73667120 3618000 728792..730312 1 NC_007354.1 Mg chelatase-like protein 730312 3618000 Ecaj_0502 Ehrlichia canis str. Jake Mg chelatase-like protein YP_303136.1 728792 D 269484 CDS YP_303137.1 73667121 3618001 730420..730752 1 NC_007354.1 hypothetical protein 730752 3618001 Ecaj_0503 Ehrlichia canis str. Jake hypothetical protein YP_303137.1 730420 D 269484 CDS YP_303138.1 73667122 3618002 complement(730872..731711) 1 NC_007354.1 ribonuclease BN 731711 3618002 Ecaj_0504 Ehrlichia canis str. Jake ribonuclease BN YP_303138.1 730872 R 269484 CDS YP_303139.1 73667123 3618003 731875..732819 1 NC_007354.1 thiamine-monophosphate kinase 732819 3618003 Ecaj_0505 Ehrlichia canis str. Jake thiamine-monophosphate kinase YP_303139.1 731875 D 269484 CDS YP_303140.1 73667124 3618004 complement(732997..733716) 1 NC_007354.1 DNA polymerase III subunit epsilon 733716 3618004 Ecaj_0506 Ehrlichia canis str. Jake DNA polymerase III subunit epsilon YP_303140.1 732997 R 269484 CDS YP_303141.1 73667125 3618005 complement(733957..735429) 1 NC_007354.1 hypothetical protein 735429 3618005 Ecaj_0507 Ehrlichia canis str. Jake hypothetical protein YP_303141.1 733957 R 269484 CDS YP_303142.1 73667126 3618006 complement(735867..737822) 1 NC_007354.1 hypothetical protein 737822 3618006 Ecaj_0508 Ehrlichia canis str. Jake hypothetical protein YP_303142.1 735867 R 269484 CDS YP_303143.1 73667127 3618007 complement(739127..740743) 1 NC_007354.1 hypothetical protein 740743 3618007 Ecaj_0509 Ehrlichia canis str. Jake hypothetical protein YP_303143.1 739127 R 269484 CDS YP_303144.1 73667128 3618008 complement(741167..741922) 1 NC_007354.1 cytochrome c1 741922 3618008 Ecaj_0510 Ehrlichia canis str. Jake cytochrome c1 YP_303144.1 741167 R 269484 CDS YP_303145.1 73667129 3618009 complement(741922..743148) 1 NC_007354.1 cytochrome b/b6 743148 3618009 Ecaj_0511 Ehrlichia canis str. Jake cytochrome b/b6 YP_303145.1 741922 R 269484 CDS YP_303146.1 73667130 3618145 complement(743173..743736) 1 NC_007354.1 ubiquinol-cytochrome c reductase, iron-sulfur subunit 743736 3618145 Ecaj_0512 Ehrlichia canis str. Jake ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_303146.1 743173 R 269484 CDS YP_303147.1 73667131 3618146 complement(744219..745091) 1 NC_007354.1 hypothetical protein 745091 3618146 Ecaj_0513 Ehrlichia canis str. Jake hypothetical protein YP_303147.1 744219 R 269484 CDS YP_303148.1 73667132 3618147 complement(745188..745991) 1 NC_007354.1 ABC transporter 745991 3618147 Ecaj_0514 Ehrlichia canis str. Jake ABC transporter YP_303148.1 745188 R 269484 CDS YP_303149.1 73667133 3618148 complement(745998..746360) 1 NC_007354.1 hypothetical protein 746360 3618148 Ecaj_0515 Ehrlichia canis str. Jake hypothetical protein YP_303149.1 745998 R 269484 CDS YP_303150.1 73667134 3618149 complement(746686..747552) 1 NC_007354.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 747552 tsf 3618149 tsf Ehrlichia canis str. Jake elongation factor Ts YP_303150.1 746686 R 269484 CDS YP_303151.1 73667135 3618150 complement(747542..748417) 1 NC_007354.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 748417 rpsB 3618150 rpsB Ehrlichia canis str. Jake 30S ribosomal protein S2 YP_303151.1 747542 R 269484 CDS YP_303152.1 73667136 3618151 complement(749077..749655) 1 NC_007354.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 749655 3618151 Ecaj_0518 Ehrlichia canis str. Jake Maf-like protein YP_303152.1 749077 R 269484 CDS YP_303153.1 73667137 3618152 complement(749648..749896) 1 NC_007354.1 translation initiation factor 1 749896 3618152 Ecaj_0519 Ehrlichia canis str. Jake translation initiation factor 1 YP_303153.1 749648 R 269484 CDS YP_303154.1 73667138 3618153 complement(750009..751079) 1 NC_007354.1 secretion protein HlyD 751079 3618153 Ecaj_0520 Ehrlichia canis str. Jake secretion protein HlyD YP_303154.1 750009 R 269484 CDS YP_303155.1 73667139 3618154 complement(751098..752498) 1 NC_007354.1 dihydrolipoamide dehydrogenase 752498 3618154 Ecaj_0521 Ehrlichia canis str. Jake dihydrolipoamide dehydrogenase YP_303155.1 751098 R 269484 CDS YP_303156.1 73667140 3618155 complement(752522..753685) 1 NC_007354.1 quinoprotein 753685 3618155 Ecaj_0522 Ehrlichia canis str. Jake quinoprotein YP_303156.1 752522 R 269484 CDS YP_303157.1 73667141 3618156 754259..755764 1 NC_007354.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 755764 3618156 Ecaj_0523 Ehrlichia canis str. Jake phosphoglyceromutase YP_303157.1 754259 D 269484 CDS YP_303158.1 73667142 3618157 complement(756740..758059) 1 NC_007354.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 758059 engA 3618157 engA Ehrlichia canis str. Jake GTP-binding protein EngA YP_303158.1 756740 R 269484 CDS YP_303159.1 73667143 3618158 758290..759405 1 NC_007354.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 759405 3618158 Ecaj_0525 Ehrlichia canis str. Jake carbamoyl phosphate synthase small subunit YP_303159.1 758290 D 269484 CDS YP_303160.1 73667144 3618159 759707..760666 1 NC_007354.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 760666 ispH 3618159 ispH Ehrlichia canis str. Jake 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_303160.1 759707 D 269484 CDS YP_303161.1 73667145 3618160 760813..761274 1 NC_007354.1 deoxyuridine 5'-triphosphate nucleotidohydrolase 761274 3618160 Ecaj_0527 Ehrlichia canis str. Jake deoxyuridine 5'-triphosphate nucleotidohydrolase YP_303161.1 760813 D 269484 CDS YP_303162.1 73667146 3618161 761965..762564 1 NC_007354.1 hypothetical protein 762564 3618161 Ecaj_0528 Ehrlichia canis str. Jake hypothetical protein YP_303162.1 761965 D 269484 CDS YP_303163.1 73667147 3618162 complement(762770..768862) 1 NC_007354.1 putative Type IV secretory pathway VirB6 components 768862 3618162 Ecaj_0529 Ehrlichia canis str. Jake putative Type IV secretory pathway VirB6 components YP_303163.1 762770 R 269484 CDS YP_303164.1 73667148 3618163 complement(768899..773233) 1 NC_007354.1 TrbL/VirB6 plasmid conjugal transfer protein 773233 3618163 Ecaj_0530 Ehrlichia canis str. Jake TrbL/VirB6 plasmid conjugal transfer protein YP_303164.1 768899 R 269484 CDS YP_303165.1 73667149 3617952 complement(773237..776044) 1 NC_007354.1 TrbL/VirB6 plasmid conjugal transfer protein 776044 3617952 Ecaj_0531 Ehrlichia canis str. Jake TrbL/VirB6 plasmid conjugal transfer protein YP_303165.1 773237 R 269484 CDS YP_303166.1 73667150 3617953 complement(776207..778726) 1 NC_007354.1 TrbL/VirB6 plasmid conjugal transfer protein 778726 3617953 Ecaj_0532 Ehrlichia canis str. Jake TrbL/VirB6 plasmid conjugal transfer protein YP_303166.1 776207 R 269484 CDS YP_303167.1 73667151 3617954 complement(778764..781166) 1 NC_007354.1 type IV secretion system ATPase VirB4 781166 3617954 Ecaj_0533 Ehrlichia canis str. Jake type IV secretion system ATPase VirB4 YP_303167.1 778764 R 269484 CDS YP_303168.1 73667152 3617955 complement(781166..781471) 1 NC_007354.1 type IV secretion system protein VirB3 781471 3617955 Ecaj_0534 Ehrlichia canis str. Jake type IV secretion system protein VirB3 YP_303168.1 781166 R 269484 CDS YP_303169.1 73667153 3617956 complement(781835..782452) 1 NC_007354.1 superoxide dismutase 782452 3617956 Ecaj_0535 Ehrlichia canis str. Jake superoxide dismutase YP_303169.1 781835 R 269484 CDS YP_303170.1 73667154 3617957 782681..783946 1 NC_007354.1 binding-protein dependent transport system inner membrane protein 783946 3617957 Ecaj_0536 Ehrlichia canis str. Jake binding-protein dependent transport system inner membrane protein YP_303170.1 782681 D 269484 CDS YP_303171.1 73667155 3617959 complement(784752..785651) 1 NC_007354.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 785651 3617959 Ecaj_0537 Ehrlichia canis str. Jake lipoyl synthase YP_303171.1 784752 R 269484 CDS YP_303172.1 73667156 3617960 complement(785915..787243) 1 NC_007354.1 hypothetical protein 787243 3617960 Ecaj_0538 Ehrlichia canis str. Jake hypothetical protein YP_303172.1 785915 R 269484 CDS YP_303173.1 73667157 3617961 complement(787805..789775) 1 NC_007354.1 carbamoyl-phosphate synthase subunit L 789775 3617961 Ecaj_0539 Ehrlichia canis str. Jake carbamoyl-phosphate synthase subunit L YP_303173.1 787805 R 269484 CDS YP_303174.1 73667158 3617962 789933..790904 1 NC_007354.1 ribosomal large subunit pseudouridine synthase D 790904 3617962 Ecaj_0540 Ehrlichia canis str. Jake ribosomal large subunit pseudouridine synthase D YP_303174.1 789933 D 269484 CDS YP_303175.1 73667159 3617963 791016..792281 1 NC_007354.1 diaminopimelate decarboxylase 792281 3617963 Ecaj_0541 Ehrlichia canis str. Jake diaminopimelate decarboxylase YP_303175.1 791016 D 269484 CDS YP_303176.1 73667160 3617964 complement(793167..793469) 1 NC_007354.1 required for 70S ribosome assembly; 50S ribosomal protein L28 793469 rpmB 3617964 rpmB Ehrlichia canis str. Jake 50S ribosomal protein L28 YP_303176.1 793167 R 269484 CDS YP_303177.1 73667161 3617966 complement(794253..796229) 1 NC_007354.1 primosomal protein n 796229 3617966 Ecaj_0544 Ehrlichia canis str. Jake primosomal protein n YP_303177.1 794253 R 269484 CDS YP_303178.1 73667162 3617967 complement(796732..797706) 1 NC_007354.1 hypothetical protein 797706 3617967 Ecaj_0545 Ehrlichia canis str. Jake hypothetical protein YP_303178.1 796732 R 269484 CDS YP_303179.1 73667163 3617968 797937..798659 1 NC_007354.1 uroporphyrinogen III synthase HEM4 798659 3617968 Ecaj_0546 Ehrlichia canis str. Jake uroporphyrinogen III synthase HEM4 YP_303179.1 797937 D 269484 CDS YP_303180.1 73667164 3617969 complement(799104..800828) 1 NC_007354.1 peptidase M24 800828 3617969 Ecaj_0547 Ehrlichia canis str. Jake peptidase M24 YP_303180.1 799104 R 269484 CDS YP_303181.1 73667165 3617970 complement(801608..802078) 1 NC_007354.1 hypothetical protein 802078 3617970 Ecaj_0548 Ehrlichia canis str. Jake hypothetical protein YP_303181.1 801608 R 269484 CDS YP_303182.1 73667166 3617933 complement(802212..803039) 1 NC_007354.1 hypothetical protein 803039 3617933 Ecaj_0549 Ehrlichia canis str. Jake hypothetical protein YP_303182.1 802212 R 269484 CDS YP_303183.1 73667167 3617934 complement(803029..803919) 1 NC_007354.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 803919 era 3617934 era Ehrlichia canis str. Jake GTP-binding protein Era YP_303183.1 803029 R 269484 CDS YP_303184.1 73667168 3617935 complement(804407..805756) 1 NC_007354.1 signal recognition particle subunit FFH/SRP54 (srp54) 805756 3617935 Ecaj_0551 Ehrlichia canis str. Jake signal recognition particle subunit FFH/SRP54 (srp54) YP_303184.1 804407 R 269484 CDS YP_303185.1 73667169 3617936 complement(805741..807336) 1 NC_007354.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 807336 3617936 Ecaj_0552 Ehrlichia canis str. Jake putative monovalent cation/H+ antiporter subunit D YP_303185.1 805741 R 269484 CDS YP_303186.1 73667170 3617937 complement(808194..808658) 1 NC_007354.1 hypothetical protein 808658 3617937 Ecaj_0553 Ehrlichia canis str. Jake hypothetical protein YP_303186.1 808194 R 269484 CDS YP_303187.1 73667171 3617938 complement(808925..810829) 1 NC_007354.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 810829 dnaK 3617938 dnaK Ehrlichia canis str. Jake molecular chaperone DnaK YP_303187.1 808925 R 269484 CDS YP_303188.1 73667172 3617939 complement(810931..812757) 1 NC_007354.1 ribonuclease E 812757 3617939 Ecaj_0555 Ehrlichia canis str. Jake ribonuclease E YP_303188.1 810931 R 269484 CDS YP_303189.1 73667173 3617940 complement(812888..813223) 1 NC_007354.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 813223 3617940 Ecaj_0556 Ehrlichia canis str. Jake putative monovalent cation/H+ antiporter subunit C YP_303189.1 812888 R 269484 CDS YP_303190.1 73667174 3617941 complement(813265..813684) 1 NC_007354.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 813684 3617941 Ecaj_0557 Ehrlichia canis str. Jake putative monovalent cation/H+ antiporter subunit B YP_303190.1 813265 R 269484 CDS YP_303191.1 73667175 3617942 complement(813677..814222) 1 NC_007354.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 814222 3617942 Ecaj_0558 Ehrlichia canis str. Jake putative monovalent cation/H+ antiporter subunit B YP_303191.1 813677 R 269484 CDS YP_303192.1 73667176 3617943 complement(814212..814493) 1 NC_007354.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit G 814493 3617943 Ecaj_0559 Ehrlichia canis str. Jake putative monovalent cation/H+ antiporter subunit G YP_303192.1 814212 R 269484 CDS YP_303193.1 73667177 3617944 complement(814508..814825) 1 NC_007354.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit F 814825 3617944 Ecaj_0560 Ehrlichia canis str. Jake putative monovalent cation/H+ antiporter subunit F YP_303193.1 814508 R 269484 CDS YP_303194.1 73667178 3617945 complement(815260..817245) 1 NC_007354.1 transketolase 817245 3617945 Ecaj_0561 Ehrlichia canis str. Jake transketolase YP_303194.1 815260 R 269484 CDS YP_303195.1 73667179 3617946 complement(817303..818778) 1 NC_007354.1 thermostable carboxypeptidase 1 818778 3617946 Ecaj_0562 Ehrlichia canis str. Jake thermostable carboxypeptidase 1 YP_303195.1 817303 R 269484 CDS YP_303196.1 73667180 3617947 819437..819925 1 NC_007354.1 OmpA/MotB domain-containing protein 819925 3617947 Ecaj_0563 Ehrlichia canis str. Jake OmpA/MotB domain-containing protein YP_303196.1 819437 D 269484 CDS YP_303197.1 73667181 3617948 820239..821534 1 NC_007354.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 821534 3617948 Ecaj_0564 Ehrlichia canis str. Jake adenylosuccinate synthetase YP_303197.1 820239 D 269484 CDS YP_303198.1 73667182 3617949 complement(822647..823117) 1 NC_007354.1 hypothetical protein 823117 3617949 Ecaj_0565 Ehrlichia canis str. Jake hypothetical protein YP_303198.1 822647 R 269484 CDS YP_303199.1 73667183 3617950 complement(823362..825230) 1 NC_007354.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 825230 3617950 Ecaj_0566 Ehrlichia canis str. Jake ribonucleotide-diphosphate reductase subunit alpha YP_303199.1 823362 R 269484 CDS YP_303200.1 73667184 3617914 825706..826557 1 NC_007354.1 farnesyl-diphosphate synthase 826557 3617914 Ecaj_0567 Ehrlichia canis str. Jake farnesyl-diphosphate synthase YP_303200.1 825706 D 269484 CDS YP_303201.1 73667185 3617915 826563..827474 1 NC_007354.1 hypothetical protein 827474 3617915 Ecaj_0568 Ehrlichia canis str. Jake hypothetical protein YP_303201.1 826563 D 269484 CDS YP_303202.1 73667186 3617917 complement(828180..829241) 1 NC_007354.1 FAD dependent oxidoreductase 829241 3617917 Ecaj_0570 Ehrlichia canis str. Jake FAD dependent oxidoreductase YP_303202.1 828180 R 269484 CDS YP_303203.1 73667187 3617918 complement(829693..831159) 1 NC_007354.1 unwinds double stranded DNA; replicative DNA helicase 831159 3617918 Ecaj_0571 Ehrlichia canis str. Jake replicative DNA helicase YP_303203.1 829693 R 269484 CDS YP_303204.1 73667188 3617919 complement(831917..832342) 1 NC_007354.1 hypothetical protein 832342 3617919 Ecaj_0572 Ehrlichia canis str. Jake hypothetical protein YP_303204.1 831917 R 269484 CDS YP_303205.1 73667189 3617920 832486..832905 1 NC_007354.1 cytidine/deoxycytidylate deaminase 832905 3617920 Ecaj_0573 Ehrlichia canis str. Jake cytidine/deoxycytidylate deaminase YP_303205.1 832486 D 269484 CDS YP_303206.1 73667190 3617921 complement(833811..834770) 1 NC_007354.1 3-oxoacyl-ACP synthase 834770 3617921 Ecaj_0574 Ehrlichia canis str. Jake 3-oxoacyl-ACP synthase YP_303206.1 833811 R 269484 CDS YP_303207.1 73667191 3617922 complement(834783..835796) 1 NC_007354.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 835796 3617922 Ecaj_0575 Ehrlichia canis str. Jake putative glycerol-3-phosphate acyltransferase PlsX YP_303207.1 834783 R 269484 CDS YP_303208.1 73667192 3617923 complement(835824..836009) 1 NC_007354.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 836009 rpmF 3617923 rpmF Ehrlichia canis str. Jake 50S ribosomal protein L32 YP_303208.1 835824 R 269484 CDS YP_303209.1 73667193 3617924 836152..837342 1 NC_007354.1 queuine/other tRNA- ribosyl transferase 837342 3617924 Ecaj_0577 Ehrlichia canis str. Jake queuine/other tRNA- ribosyl transferase YP_303209.1 836152 D 269484 CDS YP_303210.1 73667194 3617925 complement(838236..838997) 1 NC_007354.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 838997 3617925 Ecaj_0578 Ehrlichia canis str. Jake phosphate ABC transporter ATP-binding protein YP_303210.1 838236 R 269484 CDS YP_303211.1 73667195 3617926 complement(839011..839814) 1 NC_007354.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 839814 3617926 Ecaj_0579 Ehrlichia canis str. Jake dihydrodipicolinate reductase YP_303211.1 839011 R 269484 CDS YP_303212.1 73667196 3617927 complement(839811..840302) 1 NC_007354.1 flavin reductase-like protein 840302 3617927 Ecaj_0580 Ehrlichia canis str. Jake flavin reductase-like protein YP_303212.1 839811 R 269484 CDS YP_303213.1 73667197 3617928 complement(840351..841229) 1 NC_007354.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 841229 ubiA 3617928 ubiA Ehrlichia canis str. Jake 4-hydroxybenzoate polyprenyltransferase YP_303213.1 840351 R 269484 CDS YP_303214.1 73667198 3617929 complement(841704..842591) 1 NC_007354.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 842591 ubiA 3617929 ubiA Ehrlichia canis str. Jake 4-hydroxybenzoate polyprenyltransferase YP_303214.1 841704 R 269484 CDS YP_303215.1 73667199 3617930 842873..843007 1 NC_007354.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 843007 rpmH 3617930 rpmH Ehrlichia canis str. Jake 50S ribosomal protein L34 YP_303215.1 842873 D 269484 CDS YP_303216.1 73667200 3617931 842998..843357 1 NC_007354.1 hypothetical protein 843357 3617931 Ecaj_0584 Ehrlichia canis str. Jake hypothetical protein YP_303216.1 842998 D 269484 CDS YP_303217.1 73667201 3617932 843427..844737 1 NC_007354.1 Sodium:alanine symporter 844737 3617932 Ecaj_0585 Ehrlichia canis str. Jake Sodium:alanine symporter YP_303217.1 843427 D 269484 CDS YP_303218.1 73667202 3618081 complement(845542..847560) 1 NC_007354.1 ComEC/Rec2-like protein 847560 3618081 Ecaj_0586 Ehrlichia canis str. Jake ComEC/Rec2-like protein YP_303218.1 845542 R 269484 CDS YP_303219.1 73667203 3618082 complement(848251..850608) 1 NC_007354.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 850608 pheT 3618082 pheT Ehrlichia canis str. Jake phenylalanyl-tRNA synthetase subunit beta YP_303219.1 848251 R 269484 CDS YP_303220.1 73667204 3618083 complement(850652..851050) 1 NC_007354.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 851050 rplQ 3618083 rplQ Ehrlichia canis str. Jake 50S ribosomal protein L17 YP_303220.1 850652 R 269484 CDS YP_303221.1 73667205 3618084 complement(851060..852178) 1 NC_007354.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 852178 3618084 Ecaj_0589 Ehrlichia canis str. Jake DNA-directed RNA polymerase subunit alpha YP_303221.1 851060 R 269484 CDS YP_303222.1 73667206 3618085 complement(852208..852588) 1 NC_007354.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 852588 3618085 Ecaj_0590 Ehrlichia canis str. Jake 30S ribosomal protein S11 YP_303222.1 852208 R 269484 CDS YP_303223.1 73667207 3618086 complement(852600..852971) 1 NC_007354.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 852971 rpsM 3618086 rpsM Ehrlichia canis str. Jake 30S ribosomal protein S13 YP_303223.1 852600 R 269484 CDS YP_303224.1 73667208 3618087 complement(853030..853695) 1 NC_007354.1 adenylate kinase 853695 3618087 Ecaj_0592 Ehrlichia canis str. Jake adenylate kinase YP_303224.1 853030 R 269484 CDS YP_303225.1 73667209 3618088 complement(853680..854990) 1 NC_007354.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 854990 secY 3618088 secY Ehrlichia canis str. Jake preprotein translocase subunit SecY YP_303225.1 853680 R 269484 CDS YP_303226.1 73667210 3618089 complement(855018..855488) 1 NC_007354.1 late assembly protein; 50S ribosomal protein L15 855488 rplO 3618089 rplO Ehrlichia canis str. Jake 50S ribosomal protein L15 YP_303226.1 855018 R 269484 CDS YP_303227.1 73667211 3618090 complement(855492..856016) 1 NC_007354.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 856016 rpsE 3618090 rpsE Ehrlichia canis str. Jake 30S ribosomal protein S5 YP_303227.1 855492 R 269484 CDS YP_303228.1 73667212 3618091 complement(856034..856399) 1 NC_007354.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 856399 rplR 3618091 rplR Ehrlichia canis str. Jake 50S ribosomal protein L18 YP_303228.1 856034 R 269484 CDS YP_303229.1 73667213 3618092 complement(856417..856953) 1 NC_007354.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 856953 rplF 3618092 rplF Ehrlichia canis str. Jake 50S ribosomal protein L6 YP_303229.1 856417 R 269484 CDS YP_303230.1 73667214 3618093 complement(856965..857363) 1 NC_007354.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 857363 rpsH 3618093 rpsH Ehrlichia canis str. Jake 30S ribosomal protein S8 YP_303230.1 856965 R 269484 CDS YP_303231.1 73667215 3618094 complement(857386..857691) 1 NC_007354.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 857691 rpsN 3618094 rpsN Ehrlichia canis str. Jake 30S ribosomal protein S14 YP_303231.1 857386 R 269484 CDS YP_303232.1 73667216 3618095 complement(857701..858234) 1 NC_007354.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 858234 rplE 3618095 rplE Ehrlichia canis str. Jake 50S ribosomal protein L5 YP_303232.1 857701 R 269484 CDS YP_303233.1 73667217 3618096 complement(858245..858574) 1 NC_007354.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 858574 rplX 3618096 rplX Ehrlichia canis str. Jake 50S ribosomal protein L24 YP_303233.1 858245 R 269484 CDS YP_303234.1 73667218 3618097 complement(858576..858935) 1 NC_007354.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 858935 rplN 3618097 rplN Ehrlichia canis str. Jake 50S ribosomal protein L14 YP_303234.1 858576 R 269484 CDS YP_303235.1 73667219 3618098 complement(858949..859200) 1 NC_007354.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 859200 rpsQ 3618098 rpsQ Ehrlichia canis str. Jake 30S ribosomal protein S17 YP_303235.1 858949 R 269484 CDS YP_303236.1 73667220 3618099 complement(859169..859372) 1 NC_007354.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 859372 3618099 Ecaj_0604 Ehrlichia canis str. Jake 50S ribosomal protein L29 YP_303236.1 859169 R 269484 CDS YP_303237.1 73667221 3618063 complement(859385..859795) 1 NC_007354.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 859795 rplP 3618063 rplP Ehrlichia canis str. Jake 50S ribosomal protein L16 YP_303237.1 859385 R 269484 CDS YP_303238.1 73667222 3618064 complement(859812..860447) 1 NC_007354.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 860447 rpsC 3618064 rpsC Ehrlichia canis str. Jake 30S ribosomal protein S3 YP_303238.1 859812 R 269484 CDS YP_303239.1 73667223 3618065 complement(860451..860795) 1 NC_007354.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 860795 rplV 3618065 rplV Ehrlichia canis str. Jake 50S ribosomal protein L22 YP_303239.1 860451 R 269484 CDS YP_303240.1 73667224 3618066 complement(860808..861089) 1 NC_007354.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 861089 rpsS 3618066 rpsS Ehrlichia canis str. Jake 30S ribosomal protein S19 YP_303240.1 860808 R 269484 CDS YP_303241.1 73667225 3618067 complement(861093..861923) 1 NC_007354.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 861923 rplB 3618067 rplB Ehrlichia canis str. Jake 50S ribosomal protein L2 YP_303241.1 861093 R 269484 CDS YP_303242.1 73667226 3618068 complement(861931..862221) 1 NC_007354.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 862221 rplW 3618068 rplW Ehrlichia canis str. Jake 50S ribosomal protein L23 YP_303242.1 861931 R 269484 CDS YP_303243.1 73667227 3618069 complement(862218..862835) 1 NC_007354.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 862835 rplD 3618069 rplD Ehrlichia canis str. Jake 50S ribosomal protein L4 YP_303243.1 862218 R 269484 CDS YP_303244.1 73667228 3618070 complement(862843..863538) 1 NC_007354.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 863538 rplC 3618070 rplC Ehrlichia canis str. Jake 50S ribosomal protein L3 YP_303244.1 862843 R 269484 CDS YP_303245.1 73667229 3618071 complement(863531..863857) 1 NC_007354.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 863857 rpsJ 3618071 rpsJ Ehrlichia canis str. Jake 30S ribosomal protein S10 YP_303245.1 863531 R 269484 CDS YP_303246.1 73667230 3618072 complement(863865..865052) 1 NC_007354.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 865052 3618072 Ecaj_0614 Ehrlichia canis str. Jake elongation factor Tu YP_303246.1 863865 R 269484 CDS YP_303247.1 73667231 3618075 865410..866168 1 NC_007354.1 RNA methyl transferase TrmH 866168 3618075 Ecaj_0615 Ehrlichia canis str. Jake RNA methyl transferase TrmH YP_303247.1 865410 D 269484 CDS YP_303248.1 73667232 3618076 866149..866793 1 NC_007354.1 cytidylate kinase 866793 3618076 Ecaj_0616 Ehrlichia canis str. Jake cytidylate kinase YP_303248.1 866149 D 269484 CDS YP_303249.1 73667233 3618077 866858..868561 1 NC_007354.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 868561 rpsA 3618077 rpsA Ehrlichia canis str. Jake 30S ribosomal protein S1 YP_303249.1 866858 D 269484 CDS YP_303250.1 73667234 3618078 868575..869441 1 NC_007354.1 signal peptide peptidase SppA 869441 3618078 Ecaj_0618 Ehrlichia canis str. Jake signal peptide peptidase SppA YP_303250.1 868575 D 269484 CDS YP_303251.1 73667235 3618079 869447..869710 1 NC_007354.1 histone-like DNA-binding protein 869710 3618079 Ecaj_0619 Ehrlichia canis str. Jake histone-like DNA-binding protein YP_303251.1 869447 D 269484 CDS YP_303252.1 73667236 3618080 869747..870040 1 NC_007354.1 hypothetical protein 870040 3618080 Ecaj_0620 Ehrlichia canis str. Jake hypothetical protein YP_303252.1 869747 D 269484 CDS YP_303253.1 73667237 3618164 870033..870401 1 NC_007354.1 hypothetical protein 870401 3618164 Ecaj_0621 Ehrlichia canis str. Jake hypothetical protein YP_303253.1 870033 D 269484 CDS YP_303254.1 73667238 3618165 870551..871468 1 NC_007354.1 hypothetical protein 871468 3618165 Ecaj_0622 Ehrlichia canis str. Jake hypothetical protein YP_303254.1 870551 D 269484 CDS YP_303255.1 73667239 3618166 871552..872565 1 NC_007354.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 872565 hemH 3618166 hemH Ehrlichia canis str. Jake ferrochelatase YP_303255.1 871552 D 269484 CDS YP_303256.1 73667240 3618167 complement(873061..874116) 1 NC_007354.1 AFG1-like ATPase 874116 3618167 Ecaj_0624 Ehrlichia canis str. Jake AFG1-like ATPase YP_303256.1 873061 R 269484 CDS YP_303257.1 73667241 3618168 complement(874502..874840) 1 NC_007354.1 hypothetical protein 874840 3618168 Ecaj_0625 Ehrlichia canis str. Jake hypothetical protein YP_303257.1 874502 R 269484 CDS YP_303258.1 73667242 3618169 complement(875323..876180) 1 NC_007354.1 Band 7 protein 876180 3618169 Ecaj_0626 Ehrlichia canis str. Jake Band 7 protein YP_303258.1 875323 R 269484 CDS YP_303259.1 73667243 3618170 complement(876828..877283) 1 NC_007354.1 ankyrin 877283 3618170 Ecaj_0627 Ehrlichia canis str. Jake ankyrin YP_303259.1 876828 R 269484 CDS YP_303260.1 73667244 3618171 complement(877280..877636) 1 NC_007354.1 hypothetical protein 877636 3618171 Ecaj_0628 Ehrlichia canis str. Jake hypothetical protein YP_303260.1 877280 R 269484 CDS YP_303261.1 73667245 3618172 877773..880337 1 NC_007354.1 UvrD/REP helicase 880337 3618172 Ecaj_0629 Ehrlichia canis str. Jake UvrD/REP helicase YP_303261.1 877773 D 269484 CDS YP_303262.1 73667246 3618173 complement(881119..882093) 1 NC_007354.1 zinc-containing alcohol dehydrogenase superfamily protein 882093 3618173 Ecaj_0630 Ehrlichia canis str. Jake zinc-containing alcohol dehydrogenase superfamily protein YP_303262.1 881119 R 269484 CDS YP_303263.1 73667247 3618174 complement(882973..884751) 1 NC_007354.1 Type I secretion system ATPase, PrtD 884751 3618174 Ecaj_0631 Ehrlichia canis str. Jake Type I secretion system ATPase, PrtD YP_303263.1 882973 R 269484 CDS YP_303264.1 73667248 3618175 884873..885100 1 NC_007354.1 hypothetical protein 885100 3618175 Ecaj_0632 Ehrlichia canis str. Jake hypothetical protein YP_303264.1 884873 D 269484 CDS YP_303265.1 73667249 3618176 885113..885955 1 NC_007354.1 dihydropteroate synthase 885955 3618176 Ecaj_0633 Ehrlichia canis str. Jake dihydropteroate synthase YP_303265.1 885113 D 269484 CDS YP_303266.1 73667250 3618177 complement(887142..888221) 1 NC_007354.1 hypothetical protein 888221 3618177 Ecaj_0634 Ehrlichia canis str. Jake hypothetical protein YP_303266.1 887142 R 269484 CDS YP_303267.1 73667251 3618178 889021..892251 1 NC_007354.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 892251 carB 3618178 carB Ehrlichia canis str. Jake carbamoyl phosphate synthase large subunit YP_303267.1 889021 D 269484 CDS YP_303268.1 73667252 3618179 complement(892718..893014) 1 NC_007354.1 hypothetical protein 893014 3618179 Ecaj_0636 Ehrlichia canis str. Jake hypothetical protein YP_303268.1 892718 R 269484 CDS YP_303269.1 73667253 3618180 complement(893114..894499) 1 NC_007354.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 894499 fumC 3618180 fumC Ehrlichia canis str. Jake fumarate hydratase YP_303269.1 893114 R 269484 CDS YP_303270.1 73667254 3618181 894775..895419 1 NC_007354.1 DNA/pantothenate metabolism flavoprotein-domain-containin protein 895419 3618181 Ecaj_0638 Ehrlichia canis str. Jake DNA/pantothenate metabolism flavoprotein-domain-containin protein YP_303270.1 894775 D 269484 CDS YP_303271.1 73667255 3618182 895753..897096 1 NC_007354.1 dihydroorotase 897096 3618182 Ecaj_0639 Ehrlichia canis str. Jake dihydroorotase YP_303271.1 895753 D 269484 CDS YP_303272.1 73667256 3617971 complement(897847..898491) 1 NC_007354.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 898491 lipB 3617971 lipB Ehrlichia canis str. Jake lipoate-protein ligase B YP_303272.1 897847 R 269484 CDS YP_303273.1 73667257 3617972 complement(899693..900319) 1 NC_007354.1 phosphoribosylglycinamide formyltransferase 900319 3617972 Ecaj_0641 Ehrlichia canis str. Jake phosphoribosylglycinamide formyltransferase YP_303273.1 899693 R 269484 CDS YP_303274.1 73667258 3617973 complement(900459..901961) 1 NC_007354.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 901961 3617973 Ecaj_0642 Ehrlichia canis str. Jake leucyl aminopeptidase YP_303274.1 900459 R 269484 CDS YP_303275.1 73667259 3617974 902391..903065 1 NC_007354.1 intradiol ring-cleavage dioxygenase 903065 3617974 Ecaj_0643 Ehrlichia canis str. Jake intradiol ring-cleavage dioxygenase YP_303275.1 902391 D 269484 CDS YP_303276.1 73667260 3617975 903854..904096 1 NC_007354.1 hypothetical protein 904096 3617975 Ecaj_0644 Ehrlichia canis str. Jake hypothetical protein YP_303276.1 903854 D 269484 CDS YP_303277.1 73667261 3617976 complement(904238..906811) 1 NC_007354.1 ATPase AAA 906811 3617976 Ecaj_0645 Ehrlichia canis str. Jake ATPase AAA YP_303277.1 904238 R 269484 CDS YP_303278.1 73667262 3617977 907150..907875 1 NC_007354.1 short-chain dehydrogenase 907875 3617977 Ecaj_0646 Ehrlichia canis str. Jake short-chain dehydrogenase YP_303278.1 907150 D 269484 CDS YP_303279.1 73667263 3617978 complement(908789..910447) 1 NC_007354.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 910447 groEL 3617978 groEL Ehrlichia canis str. Jake chaperonin GroEL YP_303279.1 908789 R 269484 CDS YP_303280.1 73667264 3617979 complement(910541..910825) 1 NC_007354.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 910825 groES 3617979 groES Ehrlichia canis str. Jake co-chaperonin GroES YP_303280.1 910541 R 269484 CDS YP_303281.1 73667265 3617980 911086..911778 1 NC_007354.1 DNA repair protein RadC 911778 3617980 Ecaj_0649 Ehrlichia canis str. Jake DNA repair protein RadC YP_303281.1 911086 D 269484 CDS YP_303282.1 73667266 3617983 complement(913105..913899) 1 NC_007354.1 phosphoribosylformylglycinamidine synthase I 913899 3617983 Ecaj_0652 Ehrlichia canis str. Jake phosphoribosylformylglycinamidine synthase I YP_303282.1 913105 R 269484 CDS YP_303283.1 73667267 3617984 914728..916605 1 NC_007354.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 916605 3617984 Ecaj_0653 Ehrlichia canis str. Jake tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_303283.1 914728 D 269484 CDS YP_303284.1 73667268 3617985 complement(917067..917996) 1 NC_007354.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 917996 glpX 3617985 glpX Ehrlichia canis str. Jake fructose 1,6-bisphosphatase II YP_303284.1 917067 R 269484 CDS YP_303285.1 73667269 3618141 918315..918920 1 NC_007354.1 peptidase M23B 918920 3618141 Ecaj_0655 Ehrlichia canis str. Jake peptidase M23B YP_303285.1 918315 D 269484 CDS YP_303286.1 73667270 3618142 919318..919773 1 NC_007354.1 hypothetical protein 919773 3618142 Ecaj_0656 Ehrlichia canis str. Jake hypothetical protein YP_303286.1 919318 D 269484 CDS YP_303287.1 73667271 3618143 920133..921107 1 NC_007354.1 biotin synthase 921107 3618143 Ecaj_0657 Ehrlichia canis str. Jake biotin synthase YP_303287.1 920133 D 269484 CDS YP_303288.1 73667272 3617873 923693..926707 1 NC_007354.1 phosphoribosylformylglycinamidine synthase 926707 3617873 Ecaj_0658 Ehrlichia canis str. Jake phosphoribosylformylglycinamidine synthase YP_303288.1 923693 D 269484 CDS YP_303289.1 73667273 3617874 928689..929207 1 NC_007354.1 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 929207 3617874 Ecaj_0659 Ehrlichia canis str. Jake 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase YP_303289.1 928689 D 269484 CDS YP_303290.1 73667274 3617875 complement(929708..930301) 1 NC_007354.1 hypothetical protein 930301 3617875 Ecaj_0660 Ehrlichia canis str. Jake hypothetical protein YP_303290.1 929708 R 269484 CDS YP_303291.1 73667275 3617876 complement(930387..931694) 1 NC_007354.1 peptidase M48, Ste24p 931694 3617876 Ecaj_0661 Ehrlichia canis str. Jake peptidase M48, Ste24p YP_303291.1 930387 R 269484 CDS YP_303292.1 73667276 3617877 931904..932260 1 NC_007354.1 Iojap-related protein 932260 3617877 Ecaj_0662 Ehrlichia canis str. Jake Iojap-related protein YP_303292.1 931904 D 269484 CDS YP_303293.1 73667277 3617878 932689..933570 1 NC_007354.1 hypothetical protein 933570 3617878 Ecaj_0663 Ehrlichia canis str. Jake hypothetical protein YP_303293.1 932689 D 269484 CDS YP_303294.1 73667278 3617879 complement(933692..934324) 1 NC_007354.1 hypothetical protein 934324 3617879 Ecaj_0664 Ehrlichia canis str. Jake hypothetical protein YP_303294.1 933692 R 269484 CDS YP_303295.1 73667279 3617880 934473..935501 1 NC_007354.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 935501 3617880 Ecaj_0665 Ehrlichia canis str. Jake phosphoribosylaminoimidazole synthetase YP_303295.1 934473 D 269484 CDS YP_303296.1 73667280 3617881 complement(937211..938143) 1 NC_007354.1 Phage integrase, N-terminal SAM- like 938143 3617881 Ecaj_0666 Ehrlichia canis str. Jake Phage integrase, N-terminal SAM- like YP_303296.1 937211 R 269484 CDS YP_303297.1 73667281 3617882 938350..939324 1 NC_007354.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 939324 3617882 Ecaj_0667 Ehrlichia canis str. Jake NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_303297.1 938350 D 269484 CDS YP_303298.1 73667282 3617883 complement(940729..942144) 1 NC_007354.1 nitrogen assimilation regulatory protein ntrX 942144 3617883 Ecaj_0668 Ehrlichia canis str. Jake nitrogen assimilation regulatory protein ntrX YP_303298.1 940729 R 269484 CDS YP_303299.1 73667283 3617884 complement(942420..943247) 1 NC_007354.1 cell division protein FtsQ 943247 3617884 Ecaj_0669 Ehrlichia canis str. Jake cell division protein FtsQ YP_303299.1 942420 R 269484 CDS YP_303300.1 73667284 3617885 complement(944412..945353) 1 NC_007354.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 945353 3617885 Ecaj_0670 Ehrlichia canis str. Jake glutathione synthetase YP_303300.1 944412 R 269484 CDS YP_303301.1 73667285 3617886 complement(945670..946221) 1 NC_007354.1 transport-associated domain-containing protein 946221 3617886 Ecaj_0671 Ehrlichia canis str. Jake transport-associated domain-containing protein YP_303301.1 945670 R 269484 CDS YP_303302.1 73667286 3617887 946659..948431 1 NC_007354.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 948431 aspS 3617887 aspS Ehrlichia canis str. Jake aspartyl-tRNA synthetase YP_303302.1 946659 D 269484 CDS YP_303303.1 73667287 3617888 948894..949529 1 NC_007354.1 HAD family hydrolase 949529 3617888 Ecaj_0673 Ehrlichia canis str. Jake HAD family hydrolase YP_303303.1 948894 D 269484 CDS YP_303304.1 73667288 3617889 949526..950017 1 NC_007354.1 hypothetical protein 950017 3617889 Ecaj_0674 Ehrlichia canis str. Jake hypothetical protein YP_303304.1 949526 D 269484 CDS YP_303305.1 73667289 3617890 950364..952988 1 NC_007354.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 952988 3617890 Ecaj_0675 Ehrlichia canis str. Jake pyruvate phosphate dikinase YP_303305.1 950364 D 269484 CDS YP_303306.1 73667290 3617891 953454..954143 1 NC_007354.1 hypothetical protein 954143 3617891 Ecaj_0676 Ehrlichia canis str. Jake hypothetical protein YP_303306.1 953454 D 269484 CDS YP_303307.1 73667291 3618256 954321..955811 1 NC_007354.1 NADH dehydrogenase (quinone) 955811 3618256 Ecaj_0677 Ehrlichia canis str. Jake NADH dehydrogenase (quinone) YP_303307.1 954321 D 269484 CDS YP_303308.1 73667292 3618257 956080..956601 1 NC_007354.1 cytochrome c, class I 956601 3618257 Ecaj_0678 Ehrlichia canis str. Jake cytochrome c, class I YP_303308.1 956080 D 269484 CDS YP_303309.1 73667293 3618258 957053..957826 1 NC_007354.1 Alpha/beta hydrolase 957826 3618258 Ecaj_0679 Ehrlichia canis str. Jake Alpha/beta hydrolase YP_303309.1 957053 D 269484 CDS YP_303310.1 73667294 3618260 complement(958811..959713) 1 NC_007354.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 959713 3618260 Ecaj_0680 Ehrlichia canis str. Jake bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_303310.1 958811 R 269484 CDS YP_303311.1 73667295 3618261 complement(960032..960661) 1 NC_007354.1 guanylate kinase 960661 3618261 Ecaj_0681 Ehrlichia canis str. Jake guanylate kinase YP_303311.1 960032 R 269484 CDS YP_303312.1 73667296 3618262 961074..961778 1 NC_007354.1 cytochrome c-type biogenesis protein CcmC 961778 3618262 Ecaj_0682 Ehrlichia canis str. Jake cytochrome c-type biogenesis protein CcmC YP_303312.1 961074 D 269484 CDS YP_303313.1 73667297 3618263 961787..962359 1 NC_007354.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 962359 ruvA 3618263 ruvA Ehrlichia canis str. Jake Holliday junction DNA helicase RuvA YP_303313.1 961787 D 269484 CDS YP_303314.1 73667298 3618264 963546..964535 1 NC_007354.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 964535 ruvB 3618264 ruvB Ehrlichia canis str. Jake Holliday junction DNA helicase RuvB YP_303314.1 963546 D 269484 CDS YP_303315.1 73667299 3618265 complement(965902..967062) 1 NC_007354.1 Bcr/CflA subfamily drug resistance transporter 967062 3618265 Ecaj_0685 Ehrlichia canis str. Jake Bcr/CflA subfamily drug resistance transporter YP_303315.1 965902 R 269484 CDS YP_303316.1 73667300 3618266 complement(967436..968317) 1 NC_007354.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 968317 thyX 3618266 thyX Ehrlichia canis str. Jake FAD-dependent thymidylate synthase YP_303316.1 967436 R 269484 CDS YP_303317.1 73667301 3618267 complement(969251..970027) 1 NC_007354.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 970027 sdhB 3618267 sdhB Ehrlichia canis str. Jake succinate dehydrogenase iron-sulfur subunit YP_303317.1 969251 R 269484 CDS YP_303318.1 73667302 3618268 complement(970064..971860) 1 NC_007354.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 971860 sdhA 3618268 sdhA Ehrlichia canis str. Jake succinate dehydrogenase flavoprotein subunit YP_303318.1 970064 R 269484 CDS YP_303319.1 73667303 3618269 complement(972437..972700) 1 NC_007354.1 hypothetical protein 972700 3618269 Ecaj_0689 Ehrlichia canis str. Jake hypothetical protein YP_303319.1 972437 R 269484 CDS YP_303320.1 73667304 3618270 complement(972949..974694) 1 NC_007354.1 ABC transporter transmembrane protein 974694 3618270 Ecaj_0690 Ehrlichia canis str. Jake ABC transporter transmembrane protein YP_303320.1 972949 R 269484 CDS YP_303321.1 73667305 3618271 complement(974697..975026) 1 NC_007354.1 CyaY protein 975026 3618271 Ecaj_0691 Ehrlichia canis str. Jake CyaY protein YP_303321.1 974697 R 269484 CDS YP_303322.1 73667306 3618272 complement(975205..976470) 1 NC_007354.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 976470 glyA 3618272 glyA Ehrlichia canis str. Jake serine hydroxymethyltransferase YP_303322.1 975205 R 269484 CDS YP_303323.1 73667307 3618273 complement(976545..977171) 1 NC_007354.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 977171 rplI 3618273 rplI Ehrlichia canis str. Jake 50S ribosomal protein L9 YP_303323.1 976545 R 269484 CDS YP_303324.1 73667308 3618274 complement(977192..977479) 1 NC_007354.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 977479 rpsR 3618274 rpsR Ehrlichia canis str. Jake 30S ribosomal protein S18 YP_303324.1 977192 R 269484 CDS YP_303325.1 73667309 3618506 complement(977493..977822) 1 NC_007354.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 977822 rpsF 3618506 rpsF Ehrlichia canis str. Jake 30S ribosomal protein S6 YP_303325.1 977493 R 269484 CDS YP_303326.1 73667310 3617896 complement(977960..978562) 1 NC_007354.1 colicin V production protein 978562 3617896 Ecaj_0696 Ehrlichia canis str. Jake colicin V production protein YP_303326.1 977960 R 269484 CDS YP_303327.1 73667311 3617897 complement(978568..981219) 1 NC_007354.1 TRAP dicarboxylate transporter subunit DctM 981219 3617897 Ecaj_0697 Ehrlichia canis str. Jake TRAP dicarboxylate transporter subunit DctM YP_303327.1 978568 R 269484 CDS YP_303328.1 73667312 3617898 981708..983060 1 NC_007354.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 983060 3617898 Ecaj_0698 Ehrlichia canis str. Jake DNA repair protein RadA YP_303328.1 981708 D 269484 CDS YP_303329.1 73667313 3617899 983057..983554 1 NC_007354.1 hypothetical protein 983554 3617899 Ecaj_0699 Ehrlichia canis str. Jake hypothetical protein YP_303329.1 983057 D 269484 CDS YP_303330.1 73667314 3617900 984031..984261 1 NC_007354.1 BolA-like protein 984261 3617900 Ecaj_0700 Ehrlichia canis str. Jake BolA-like protein YP_303330.1 984031 D 269484 CDS YP_303331.1 73667315 3617901 984268..984600 1 NC_007354.1 glutaredoxin-like protein 984600 3617901 Ecaj_0701 Ehrlichia canis str. Jake glutaredoxin-like protein YP_303331.1 984268 D 269484 CDS YP_303332.1 73667316 3617902 984628..986661 1 NC_007354.1 NAD-dependent DNA ligase 986661 3617902 Ecaj_0702 Ehrlichia canis str. Jake NAD-dependent DNA ligase YP_303332.1 984628 D 269484 CDS YP_303333.1 73667317 3617903 complement(987899..989059) 1 NC_007354.1 3'-5' exonuclease 989059 3617903 Ecaj_0703 Ehrlichia canis str. Jake 3'-5' exonuclease YP_303333.1 987899 R 269484 CDS YP_303334.1 73667318 3617904 complement(989228..991369) 1 NC_007354.1 sensor histidine kinase 991369 3617904 Ecaj_0704 Ehrlichia canis str. Jake sensor histidine kinase YP_303334.1 989228 R 269484 CDS YP_303335.1 73667319 3617905 complement(991540..991803) 1 NC_007354.1 cold-shock DNA-binding protein family protein 991803 3617905 Ecaj_0705 Ehrlichia canis str. Jake cold-shock DNA-binding protein family protein YP_303335.1 991540 R 269484 CDS YP_303336.1 73667320 3617906 992226..993047 1 NC_007354.1 hypothetical protein 993047 3617906 Ecaj_0706 Ehrlichia canis str. Jake hypothetical protein YP_303336.1 992226 D 269484 CDS YP_303337.1 73667321 3617907 993349..993912 1 NC_007354.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 993912 dcd 3617907 dcd Ehrlichia canis str. Jake deoxycytidine triphosphate deaminase YP_303337.1 993349 D 269484 CDS YP_303338.1 73667322 3617908 994144..994776 1 NC_007354.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 994776 3617908 Ecaj_0708 Ehrlichia canis str. Jake cytochrome c biogenesis protein CcmA YP_303338.1 994144 D 269484 CDS YP_303339.1 73667323 3617909 complement(995307..996350) 1 NC_007354.1 cytochrome oxidase assembly 996350 3617909 Ecaj_0709 Ehrlichia canis str. Jake cytochrome oxidase assembly YP_303339.1 995307 R 269484 CDS YP_303340.1 73667324 3617910 996800..997540 1 NC_007354.1 DSBA oxidoreductase 997540 3617910 Ecaj_0710 Ehrlichia canis str. Jake DSBA oxidoreductase YP_303340.1 996800 D 269484 CDS YP_303341.1 73667325 3617911 complement(997580..1000903) 1 NC_007354.1 hypothetical protein 1000903 3617911 Ecaj_0711 Ehrlichia canis str. Jake hypothetical protein YP_303341.1 997580 R 269484 CDS YP_303342.1 73667326 3617912 complement(1001167..1002408) 1 NC_007354.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1002408 hisS 3617912 hisS Ehrlichia canis str. Jake histidyl-tRNA synthetase YP_303342.1 1001167 R 269484 CDS YP_303343.1 73667327 3617913 1002560..1003336 1 NC_007354.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1003336 3617913 Ecaj_0713 Ehrlichia canis str. Jake phosphoribosylaminoimidazole-succinocarboxamide synthase YP_303343.1 1002560 D 269484 CDS YP_303344.1 73667328 3618107 complement(1003557..1005113) 1 NC_007354.1 hypothetical protein 1005113 3618107 Ecaj_0714 Ehrlichia canis str. Jake hypothetical protein YP_303344.1 1003557 R 269484 CDS YP_303345.1 73667329 3618108 complement(1005217..1010973) 1 NC_007354.1 hypothetical protein 1010973 3618108 Ecaj_0715 Ehrlichia canis str. Jake hypothetical protein YP_303345.1 1005217 R 269484 CDS YP_303346.1 73667330 3618109 complement(1011247..1016052) 1 NC_007354.1 hypothetical protein 1016052 3618109 Ecaj_0716 Ehrlichia canis str. Jake hypothetical protein YP_303346.1 1011247 R 269484 CDS YP_303347.1 73667331 3618110 complement(1016625..1017305) 1 NC_007354.1 hypothetical protein 1017305 3618110 Ecaj_0717 Ehrlichia canis str. Jake hypothetical protein YP_303347.1 1016625 R 269484 CDS YP_303348.1 73667332 3618111 complement(1018260..1019030) 1 NC_007354.1 hypothetical protein 1019030 3618111 Ecaj_0718 Ehrlichia canis str. Jake hypothetical protein YP_303348.1 1018260 R 269484 CDS YP_303349.1 73667333 3618112 complement(1020092..1020718) 1 NC_007354.1 hypothetical protein 1020718 3618112 Ecaj_0719 Ehrlichia canis str. Jake hypothetical protein YP_303349.1 1020092 R 269484 CDS YP_303350.1 73667334 3618113 complement(1021455..1022120) 1 NC_007354.1 hypothetical protein 1022120 3618113 Ecaj_0720 Ehrlichia canis str. Jake hypothetical protein YP_303350.1 1021455 R 269484 CDS YP_303351.1 73667335 3618114 complement(1023542..1024213) 1 NC_007354.1 hypothetical protein 1024213 3618114 Ecaj_0721 Ehrlichia canis str. Jake hypothetical protein YP_303351.1 1023542 R 269484 CDS YP_303352.1 73667336 3618115 complement(1025370..1025582) 1 NC_007354.1 hypothetical protein 1025582 3618115 Ecaj_0722 Ehrlichia canis str. Jake hypothetical protein YP_303352.1 1025370 R 269484 CDS YP_303353.1 73667337 3618116 complement(1026243..1026989) 1 NC_007354.1 hypothetical protein 1026989 3618116 Ecaj_0723 Ehrlichia canis str. Jake hypothetical protein YP_303353.1 1026243 R 269484 CDS YP_303354.1 73667338 3618117 complement(1027259..1027669) 1 NC_007354.1 hypothetical protein 1027669 3618117 Ecaj_0724 Ehrlichia canis str. Jake hypothetical protein YP_303354.1 1027259 R 269484 CDS YP_303355.1 73667339 3618118 complement(1028355..1028927) 1 NC_007354.1 hypothetical protein 1028927 3618118 Ecaj_0725 Ehrlichia canis str. Jake hypothetical protein YP_303355.1 1028355 R 269484 CDS YP_303356.1 73667340 3618119 complement(1029271..1029915) 1 NC_007354.1 hypothetical protein 1029915 3618119 Ecaj_0726 Ehrlichia canis str. Jake hypothetical protein YP_303356.1 1029271 R 269484 CDS YP_303357.1 73667341 3618120 complement(1031113..1031406) 1 NC_007354.1 hypothetical protein 1031406 3618120 Ecaj_0727 Ehrlichia canis str. Jake hypothetical protein YP_303357.1 1031113 R 269484 CDS YP_303358.1 73667342 3618121 complement(1031981..1032667) 1 NC_007354.1 hypothetical protein 1032667 3618121 Ecaj_0728 Ehrlichia canis str. Jake hypothetical protein YP_303358.1 1031981 R 269484 CDS YP_303359.1 73667343 3618122 complement(1033232..1033540) 1 NC_007354.1 hypothetical protein 1033540 3618122 Ecaj_0729 Ehrlichia canis str. Jake hypothetical protein YP_303359.1 1033232 R 269484 CDS YP_303360.1 73667344 3618123 complement(1034526..1035023) 1 NC_007354.1 hypothetical protein 1035023 3618123 Ecaj_0730 Ehrlichia canis str. Jake hypothetical protein YP_303360.1 1034526 R 269484 CDS YP_303361.1 73667345 3618124 complement(1035307..1035969) 1 NC_007354.1 hypothetical protein 1035969 3618124 Ecaj_0731 Ehrlichia canis str. Jake hypothetical protein YP_303361.1 1035307 R 269484 CDS YP_303362.1 73667346 3618125 complement(1036128..1036469) 1 NC_007354.1 hypothetical protein 1036469 3618125 Ecaj_0732 Ehrlichia canis str. Jake hypothetical protein YP_303362.1 1036128 R 269484 CDS YP_303363.1 73667347 3618126 complement(1037138..1037617) 1 NC_007354.1 hypothetical protein 1037617 3618126 Ecaj_0733 Ehrlichia canis str. Jake hypothetical protein YP_303363.1 1037138 R 269484 CDS YP_303364.1 73667348 3617835 complement(1038293..1038691) 1 NC_007354.1 hypothetical protein 1038691 3617835 Ecaj_0734 Ehrlichia canis str. Jake hypothetical protein YP_303364.1 1038293 R 269484 CDS YP_303365.1 73667349 3617836 complement(1038799..1039101) 1 NC_007354.1 hypothetical protein 1039101 3617836 Ecaj_0735 Ehrlichia canis str. Jake hypothetical protein YP_303365.1 1038799 R 269484 CDS YP_303366.1 73667350 3617837 complement(1040060..1040626) 1 NC_007354.1 hypothetical protein 1040626 3617837 Ecaj_0736 Ehrlichia canis str. Jake hypothetical protein YP_303366.1 1040060 R 269484 CDS YP_303367.1 73667351 3617838 complement(1040807..1041355) 1 NC_007354.1 hypothetical protein 1041355 3617838 Ecaj_0737 Ehrlichia canis str. Jake hypothetical protein YP_303367.1 1040807 R 269484 CDS YP_303368.1 73667352 3617839 complement(1041910..1042335) 1 NC_007354.1 hypothetical protein 1042335 3617839 Ecaj_0738 Ehrlichia canis str. Jake hypothetical protein YP_303368.1 1041910 R 269484 CDS YP_303369.1 73667353 3617840 complement(1042578..1043240) 1 NC_007354.1 hypothetical protein 1043240 3617840 Ecaj_0739 Ehrlichia canis str. Jake hypothetical protein YP_303369.1 1042578 R 269484 CDS YP_303370.1 73667354 3617841 complement(1043770..1044354) 1 NC_007354.1 hypothetical protein 1044354 3617841 Ecaj_0740 Ehrlichia canis str. Jake hypothetical protein YP_303370.1 1043770 R 269484 CDS YP_303371.1 73667355 3617842 complement(1044567..1044911) 1 NC_007354.1 hypothetical protein 1044911 3617842 Ecaj_0741 Ehrlichia canis str. Jake hypothetical protein YP_303371.1 1044567 R 269484 CDS YP_303372.1 73667356 3617843 complement(1044915..1045121) 1 NC_007354.1 hypothetical protein 1045121 3617843 Ecaj_0742 Ehrlichia canis str. Jake hypothetical protein YP_303372.1 1044915 R 269484 CDS YP_303373.1 73667357 3617844 complement(1046186..1046440) 1 NC_007354.1 hypothetical protein 1046440 3617844 Ecaj_0743 Ehrlichia canis str. Jake hypothetical protein YP_303373.1 1046186 R 269484 CDS YP_303374.1 73667358 3617845 complement(1046428..1046811) 1 NC_007354.1 hypothetical protein 1046811 3617845 Ecaj_0744 Ehrlichia canis str. Jake hypothetical protein YP_303374.1 1046428 R 269484 CDS YP_303375.1 73667359 3617846 complement(1046820..1047116) 1 NC_007354.1 hypothetical protein 1047116 3617846 Ecaj_0745 Ehrlichia canis str. Jake hypothetical protein YP_303375.1 1046820 R 269484 CDS YP_303376.1 73667360 3617847 complement(1047524..1048255) 1 NC_007354.1 hypothetical protein 1048255 3617847 Ecaj_0746 Ehrlichia canis str. Jake hypothetical protein YP_303376.1 1047524 R 269484 CDS YP_303377.1 73667361 3617848 complement(1048381..1048803) 1 NC_007354.1 hypothetical protein 1048803 3617848 Ecaj_0747 Ehrlichia canis str. Jake hypothetical protein YP_303377.1 1048381 R 269484 CDS YP_303378.1 73667362 3617849 complement(1049653..1050018) 1 NC_007354.1 hypothetical protein 1050018 3617849 Ecaj_0748 Ehrlichia canis str. Jake hypothetical protein YP_303378.1 1049653 R 269484 CDS YP_303379.1 73667363 3617850 complement(1050805..1051236) 1 NC_007354.1 hypothetical protein 1051236 3617850 Ecaj_0749 Ehrlichia canis str. Jake hypothetical protein YP_303379.1 1050805 R 269484 CDS YP_303380.1 73667364 3617851 1051316..1051885 1 NC_007354.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 1051885 3617851 Ecaj_0750 Ehrlichia canis str. Jake 3-methyladenine DNA glycosylase YP_303380.1 1051316 D 269484 CDS YP_303381.1 73667365 3617852 complement(1052373..1053101) 1 NC_007354.1 hypothetical protein 1053101 3617852 Ecaj_0751 Ehrlichia canis str. Jake hypothetical protein YP_303381.1 1052373 R 269484 CDS YP_303382.1 73667366 3617853 complement(1053607..1054428) 1 NC_007354.1 hypothetical protein 1054428 3617853 Ecaj_0752 Ehrlichia canis str. Jake hypothetical protein YP_303382.1 1053607 R 269484 CDS YP_303383.1 73667367 3618313 complement(1054930..1055745) 1 NC_007354.1 hypothetical protein 1055745 3618313 Ecaj_0753 Ehrlichia canis str. Jake hypothetical protein YP_303383.1 1054930 R 269484 CDS YP_303384.1 73667368 3618314 complement(1056313..1057122) 1 NC_007354.1 hypothetical protein 1057122 3618314 Ecaj_0754 Ehrlichia canis str. Jake hypothetical protein YP_303384.1 1056313 R 269484 CDS YP_303385.1 73667369 3618315 complement(1058048..1058776) 1 NC_007354.1 hypothetical protein 1058776 3618315 Ecaj_0755 Ehrlichia canis str. Jake hypothetical protein YP_303385.1 1058048 R 269484 CDS YP_303386.1 73667370 3618316 complement(1059319..1060317) 1 NC_007354.1 hypothetical protein 1060317 3618316 Ecaj_0756 Ehrlichia canis str. Jake hypothetical protein YP_303386.1 1059319 R 269484 CDS YP_303387.1 73667371 3618317 complement(1060776..1061426) 1 NC_007354.1 phosphatidate cytidylyltransferase 1061426 3618317 Ecaj_0757 Ehrlichia canis str. Jake phosphatidate cytidylyltransferase YP_303387.1 1060776 R 269484 CDS YP_303388.1 73667372 3618318 complement(1062073..1062630) 1 NC_007354.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1062630 frr 3618318 frr Ehrlichia canis str. Jake ribosome recycling factor YP_303388.1 1062073 R 269484 CDS YP_303389.1 73667373 3618319 complement(1062654..1063388) 1 NC_007354.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1063388 pyrH 3618319 pyrH Ehrlichia canis str. Jake uridylate kinase YP_303389.1 1062654 R 269484 CDS YP_303390.1 73667374 3618320 complement(1063939..1066929) 1 NC_007354.1 hypothetical protein 1066929 3618320 Ecaj_0760 Ehrlichia canis str. Jake hypothetical protein YP_303390.1 1063939 R 269484 CDS YP_303391.1 73667375 3618321 complement(1067042..1067482) 1 NC_007354.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1067482 rnhA 3618321 rnhA Ehrlichia canis str. Jake ribonuclease H YP_303391.1 1067042 R 269484 CDS YP_303392.1 73667376 3618322 1069271..1070332 1 NC_007354.1 hypothetical protein 1070332 3618322 Ecaj_0762 Ehrlichia canis str. Jake hypothetical protein YP_303392.1 1069271 D 269484 CDS YP_303393.1 73667377 3618323 1071250..1071825 1 NC_007354.1 hypothetical protein 1071825 3618323 Ecaj_0764 Ehrlichia canis str. Jake hypothetical protein YP_303393.1 1071250 D 269484 CDS YP_303394.1 73667378 3618324 1073495..1076881 1 NC_007354.1 transcription-repair coupling factor 1076881 3618324 Ecaj_0765 Ehrlichia canis str. Jake transcription-repair coupling factor YP_303394.1 1073495 D 269484 CDS YP_303395.1 73667379 3618325 complement(1078071..1078265) 1 NC_007354.1 hypothetical protein 1078265 3618325 Ecaj_0766 Ehrlichia canis str. Jake hypothetical protein YP_303395.1 1078071 R 269484 CDS YP_303396.1 73667380 3618326 complement(1078533..1078808) 1 NC_007354.1 hypothetical protein 1078808 3618326 Ecaj_0767 Ehrlichia canis str. Jake hypothetical protein YP_303396.1 1078533 R 269484 CDS YP_303397.1 73667381 3618327 complement(1079302..1079439) 1 NC_007354.1 hypothetical protein 1079439 3618327 Ecaj_0768 Ehrlichia canis str. Jake hypothetical protein YP_303397.1 1079302 R 269484 CDS YP_303398.1 73667382 3618328 complement(1079441..1079632) 1 NC_007354.1 hypothetical protein 1079632 3618328 Ecaj_0769 Ehrlichia canis str. Jake hypothetical protein YP_303398.1 1079441 R 269484 CDS YP_303399.1 73667383 3618329 complement(1079865..1080185) 1 NC_007354.1 hypothetical protein 1080185 3618329 Ecaj_0770 Ehrlichia canis str. Jake hypothetical protein YP_303399.1 1079865 R 269484 CDS YP_303400.1 73667384 3618330 complement(1080954..1081691) 1 NC_007354.1 hypothetical protein 1081691 3618330 Ecaj_0771 Ehrlichia canis str. Jake hypothetical protein YP_303400.1 1080954 R 269484 CDS YP_303401.1 73667385 3618331 complement(1082377..1082868) 1 NC_007354.1 hypothetical protein 1082868 3618331 Ecaj_0772 Ehrlichia canis str. Jake hypothetical protein YP_303401.1 1082377 R 269484 CDS YP_303402.2 161702945 3618332 1083100..1083708 1 NC_007354.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1083708 3618332 Ecaj_0773 Ehrlichia canis str. Jake riboflavin synthase subunit alpha YP_303402.2 1083100 D 269484 CDS YP_303403.1 73667387 3617705 complement(1083844..1085247) 1 NC_007354.1 hypothetical protein 1085247 3617705 Ecaj_0774 Ehrlichia canis str. Jake hypothetical protein YP_303403.1 1083844 R 269484 CDS YP_303404.1 73667388 3617706 1085763..1087028 1 NC_007354.1 insulinase-like:peptidase M16, C-terminal 1087028 3617706 Ecaj_0775 Ehrlichia canis str. Jake insulinase-like:peptidase M16, C-terminal YP_303404.1 1085763 D 269484 CDS YP_303405.1 73667389 3617707 complement(1087456..1088175) 1 NC_007354.1 hypothetical protein 1088175 3617707 Ecaj_0776 Ehrlichia canis str. Jake hypothetical protein YP_303405.1 1087456 R 269484 CDS YP_303406.1 73667390 3617708 complement(1088262..1088795) 1 NC_007354.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1088795 3617708 Ecaj_0777 Ehrlichia canis str. Jake preprotein translocase subunit SecB YP_303406.1 1088262 R 269484 CDS YP_303407.1 73667391 3617709 1088910..1089548 1 NC_007354.1 membrane translocase subunit Tim44 1089548 3617709 Ecaj_0778 Ehrlichia canis str. Jake membrane translocase subunit Tim44 YP_303407.1 1088910 D 269484 CDS YP_303408.1 73667392 3617710 complement(1090576..1091811) 1 NC_007354.1 permease, putative 1091811 3617710 Ecaj_0779 Ehrlichia canis str. Jake permease, putative YP_303408.1 1090576 R 269484 CDS YP_303409.1 73667393 3617711 complement(1091879..1092487) 1 NC_007354.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1092487 3617711 Ecaj_0780 Ehrlichia canis str. Jake thymidylate kinase YP_303409.1 1091879 R 269484 CDS YP_303410.1 73667394 3617712 complement(1092749..1093729) 1 NC_007354.1 malonyl CoA-acyl carrier protein transacylase 1093729 3617712 Ecaj_0781 Ehrlichia canis str. Jake malonyl CoA-acyl carrier protein transacylase YP_303410.1 1092749 R 269484 CDS YP_303411.2 161702944 3617713 1093901..1094128 1 NC_007354.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1094128 rpmE 3617713 rpmE Ehrlichia canis str. Jake 50S ribosomal protein L31 YP_303411.2 1093901 D 269484 CDS YP_303412.1 73667396 3617714 1094166..1094957 1 NC_007354.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1094957 ppnK 3617714 ppnK Ehrlichia canis str. Jake inorganic polyphosphate/ATP-NAD kinase YP_303412.1 1094166 D 269484 CDS YP_303413.1 73667397 3617715 1095154..1096611 1 NC_007354.1 inosine-5'-monophosphate dehydrogenase 1096611 3617715 Ecaj_0784 Ehrlichia canis str. Jake inosine-5'-monophosphate dehydrogenase YP_303413.1 1095154 D 269484 CDS YP_303414.1 73667398 3617718 1102054..1102905 1 NC_007354.1 Alpha/beta hydrolase 1102905 3617718 Ecaj_0785 Ehrlichia canis str. Jake Alpha/beta hydrolase YP_303414.1 1102054 D 269484 CDS YP_303415.1 73667399 3617719 1103119..1104102 1 NC_007354.1 pyruvate dehydrogenase (lipoamide) 1104102 3617719 Ecaj_0786 Ehrlichia canis str. Jake pyruvate dehydrogenase (lipoamide) YP_303415.1 1103119 D 269484 CDS YP_303416.1 73667400 3617720 1104922..1105734 1 NC_007354.1 conjugal transfer protein TrbG/VirB9/CagX 1105734 3617720 Ecaj_0787 Ehrlichia canis str. Jake conjugal transfer protein TrbG/VirB9/CagX YP_303416.1 1104922 D 269484 CDS YP_303417.1 73667401 3617721 1106543..1106875 1 NC_007354.1 thioredoxin 1106875 3617721 Ecaj_0788 Ehrlichia canis str. Jake thioredoxin YP_303417.1 1106543 D 269484 CDS YP_303418.1 73667402 3617578 complement(1108752..1109987) 1 NC_007354.1 tRNA 2-methylthioadenosine synthase 1109987 3617578 Ecaj_0789 Ehrlichia canis str. Jake tRNA 2-methylthioadenosine synthase YP_303418.1 1108752 R 269484 CDS YP_303419.1 73667403 3617579 complement(1110510..1110698) 1 NC_007354.1 exodeoxyribonuclease VII small subunit 1110698 3617579 Ecaj_0790 Ehrlichia canis str. Jake exodeoxyribonuclease VII small subunit YP_303419.1 1110510 R 269484 CDS YP_303420.1 73667404 3617580 1110765..1111058 1 NC_007354.1 ETC complex I subunit region 1111058 3617580 Ecaj_0791 Ehrlichia canis str. Jake ETC complex I subunit region YP_303420.1 1110765 D 269484 CDS YP_303421.1 73667405 3617581 1111914..1112831 1 NC_007354.1 auxin efflux carrier 1112831 3617581 Ecaj_0792 Ehrlichia canis str. Jake auxin efflux carrier YP_303421.1 1111914 D 269484 CDS YP_303422.1 73667406 3617582 complement(1113378..1113926) 1 NC_007354.1 hypothetical protein 1113926 3617582 Ecaj_0793 Ehrlichia canis str. Jake hypothetical protein YP_303422.1 1113378 R 269484 CDS YP_303423.1 73667407 3617583 complement(1113932..1115131) 1 NC_007354.1 hypothetical protein 1115131 3617583 Ecaj_0794 Ehrlichia canis str. Jake hypothetical protein YP_303423.1 1113932 R 269484 CDS YP_303424.1 73667408 3617585 complement(1116686..1118017) 1 NC_007354.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1118017 gltX 3617585 gltX Ehrlichia canis str. Jake glutamyl-tRNA synthetase YP_303424.1 1116686 R 269484 CDS YP_303425.1 73667409 3617586 1118334..1118696 1 NC_007354.1 hypothetical protein 1118696 3617586 Ecaj_0796 Ehrlichia canis str. Jake hypothetical protein YP_303425.1 1118334 D 269484 CDS YP_303426.1 73667410 3617587 complement(1119526..1120311) 1 NC_007354.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 1120311 thiG 3617587 thiG Ehrlichia canis str. Jake thiazole synthase YP_303426.1 1119526 R 269484 CDS YP_303427.1 73667411 3617588 complement(1120431..1120607) 1 NC_007354.1 putative ThiS sulfur transfer protein 1120607 3617588 Ecaj_0798 Ehrlichia canis str. Jake putative ThiS sulfur transfer protein YP_303427.1 1120431 R 269484 CDS YP_303428.1 73667412 3617589 1120888..1122312 1 NC_007354.1 hypothetical protein 1122312 3617589 Ecaj_0799 Ehrlichia canis str. Jake hypothetical protein YP_303428.1 1120888 D 269484 CDS YP_303429.1 73667413 3617590 complement(1123265..1123825) 1 NC_007354.1 nitrogen-fixing NifU, C-terminal 1123825 3617590 Ecaj_0800 Ehrlichia canis str. Jake nitrogen-fixing NifU, C-terminal YP_303429.1 1123265 R 269484 CDS YP_303430.1 73667414 3617591 1123836..1124258 1 NC_007354.1 heat shock protein DnaJ, N-terminal 1124258 3617591 Ecaj_0801 Ehrlichia canis str. Jake heat shock protein DnaJ, N-terminal YP_303430.1 1123836 D 269484 CDS YP_303431.1 73667415 3617592 1124455..1124760 1 NC_007354.1 hypothetical protein 1124760 3617592 Ecaj_0802 Ehrlichia canis str. Jake hypothetical protein YP_303431.1 1124455 D 269484 CDS YP_303432.1 73667416 3617593 complement(1125867..1127276) 1 NC_007354.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1127276 rho 3617593 rho Ehrlichia canis str. Jake transcription termination factor Rho YP_303432.1 1125867 R 269484 CDS YP_303433.1 73667417 3617594 1128152..1128721 1 NC_007354.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1128721 3617594 Ecaj_0804 Ehrlichia canis str. Jake ATP-dependent protease peptidase subunit YP_303433.1 1128152 D 269484 CDS YP_303434.1 73667418 3617595 1128723..1130201 1 NC_007354.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1130201 hslU 3617595 hslU Ehrlichia canis str. Jake ATP-dependent protease ATP-binding subunit HslU YP_303434.1 1128723 D 269484 CDS YP_303435.1 73667419 3617596 1130204..1130899 1 NC_007354.1 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase / demethylmenaquinone methyltransferase 1130899 3617596 Ecaj_0806 Ehrlichia canis str. Jake 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase / demethylmenaquinone methyltransferase YP_303435.1 1130204 D 269484 CDS YP_303436.1 73667420 3617805 complement(1132760..1134280) 1 NC_007354.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1134280 3617805 Ecaj_0807 Ehrlichia canis str. Jake methionyl-tRNA synthetase YP_303436.1 1132760 R 269484 CDS YP_303437.1 73667421 3617806 1134906..1136159 1 NC_007354.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1136159 3617806 Ecaj_0808 Ehrlichia canis str. Jake aspartate kinase YP_303437.1 1134906 D 269484 CDS YP_303438.1 73667422 3617807 1136718..1137461 1 NC_007354.1 cytochrome-c oxidase 1137461 3617807 Ecaj_0809 Ehrlichia canis str. Jake cytochrome-c oxidase YP_303438.1 1136718 D 269484 CDS YP_303439.1 73667423 3617808 1137470..1139026 1 NC_007354.1 cytochrome-c oxidase 1139026 3617808 Ecaj_0810 Ehrlichia canis str. Jake cytochrome-c oxidase YP_303439.1 1137470 D 269484 CDS YP_303440.1 73667424 3617809 1139029..1139916 1 NC_007354.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 1139916 3617809 Ecaj_0811 Ehrlichia canis str. Jake protoheme IX farnesyltransferase YP_303440.1 1139029 D 269484 CDS YP_303441.1 73667425 3617810 complement(1141023..1141787) 1 NC_007354.1 hypothetical protein 1141787 3617810 Ecaj_0812 Ehrlichia canis str. Jake hypothetical protein YP_303441.1 1141023 R 269484 CDS YP_303442.1 73667426 3617811 1141970..1143235 1 NC_007354.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1143235 3617811 Ecaj_0813 Ehrlichia canis str. Jake phosphoribosylamine--glycine ligase YP_303442.1 1141970 D 269484 CDS YP_303443.1 73667427 3617812 1144299..1144745 1 NC_007354.1 protein translocase subunit yajC 1144745 3617812 Ecaj_0814 Ehrlichia canis str. Jake protein translocase subunit yajC YP_303443.1 1144299 D 269484 CDS YP_303444.1 73667428 3617813 complement(1144847..1145974) 1 NC_007354.1 DNA polymerase III subunit beta 1145974 3617813 Ecaj_0815 Ehrlichia canis str. Jake DNA polymerase III subunit beta YP_303444.1 1144847 R 269484 CDS YP_303445.1 73667429 3617814 complement(1146059..1146709) 1 NC_007354.1 3'-5' exonuclease 1146709 3617814 Ecaj_0816 Ehrlichia canis str. Jake 3'-5' exonuclease YP_303445.1 1146059 R 269484 CDS YP_303446.1 73667430 3617815 complement(1146762..1147562) 1 NC_007354.1 response regulator receiver: C terminal 1147562 3617815 Ecaj_0817 Ehrlichia canis str. Jake response regulator receiver: C terminal YP_303446.1 1146762 R 269484 CDS YP_303447.1 73667431 3617816 complement(1147944..1148579) 1 NC_007354.1 transcriptional regulator 1148579 3617816 Ecaj_0818 Ehrlichia canis str. Jake transcriptional regulator YP_303447.1 1147944 R 269484 CDS YP_303448.1 73667432 3617817 complement(1149137..1149655) 1 NC_007354.1 inorganic diphosphatase 1149655 3617817 Ecaj_0819 Ehrlichia canis str. Jake inorganic diphosphatase YP_303448.1 1149137 R 269484 CDS YP_303449.1 73667433 3617818 complement(1150891..1151931) 1 NC_007354.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 1151931 argC 3617818 argC Ehrlichia canis str. Jake N-acetyl-gamma-glutamyl-phosphate reductase YP_303449.1 1150891 R 269484 CDS YP_303450.1 73667434 3617819 complement(1151940..1152389) 1 NC_007354.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1152389 rpsI 3617819 rpsI Ehrlichia canis str. Jake 30S ribosomal protein S9 YP_303450.1 1151940 R 269484 CDS YP_303451.1 73667435 3617820 complement(1152389..1152859) 1 NC_007354.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1152859 rplM 3617820 rplM Ehrlichia canis str. Jake 50S ribosomal protein L13 YP_303451.1 1152389 R 269484 CDS YP_303452.1 73667436 3617821 1153336..1154634 1 NC_007354.1 Outer membrane efflux protein 1154634 3617821 Ecaj_0823 Ehrlichia canis str. Jake Outer membrane efflux protein YP_303452.1 1153336 D 269484 CDS YP_303453.1 73667437 3617822 1154646..1155374 1 NC_007354.1 hypothetical protein 1155374 3617822 Ecaj_0824 Ehrlichia canis str. Jake hypothetical protein YP_303453.1 1154646 D 269484 CDS YP_303454.1 73667438 3617823 complement(1156481..1157536) 1 NC_007354.1 hypothetical protein 1157536 3617823 Ecaj_0825 Ehrlichia canis str. Jake hypothetical protein YP_303454.1 1156481 R 269484 CDS YP_303455.1 73667439 3617747 1157655..1158611 1 NC_007354.1 ribose-phosphate pyrophosphokinase 1158611 3617747 Ecaj_0826 Ehrlichia canis str. Jake ribose-phosphate pyrophosphokinase YP_303455.1 1157655 D 269484 CDS YP_303456.1 73667440 3617748 1158626..1158970 1 NC_007354.1 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C 1158970 3617748 Ecaj_0827 Ehrlichia canis str. Jake aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C YP_303456.1 1158626 D 269484 CDS YP_303457.1 73667441 3617749 complement(1159896..1162547) 1 NC_007354.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1162547 3617749 Ecaj_0828 Ehrlichia canis str. Jake aconitate hydratase YP_303457.1 1159896 R 269484 CDS YP_303458.1 73667442 3617750 complement(1163034..1163438) 1 NC_007354.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 1163438 apaG 3617750 apaG Ehrlichia canis str. Jake ApaG protein YP_303458.1 1163034 R 269484 CDS YP_303459.1 73667443 3617751 1163734..1164825 1 NC_007354.1 phosphoribosylaminoimidazole carboxylase 1164825 3617751 Ecaj_0830 Ehrlichia canis str. Jake phosphoribosylaminoimidazole carboxylase YP_303459.1 1163734 D 269484 CDS YP_303460.1 73667444 3617752 1165161..1166003 1 NC_007354.1 surface antigen msp4 1166003 3617752 Ecaj_0831 Ehrlichia canis str. Jake surface antigen msp4 YP_303460.1 1165161 D 269484 CDS YP_303461.1 73667445 3617753 1166331..1167161 1 NC_007354.1 surface antigen msp4 1167161 3617753 Ecaj_0832 Ehrlichia canis str. Jake surface antigen msp4 YP_303461.1 1166331 D 269484 CDS YP_303462.1 73667446 3617754 1167372..1168235 1 NC_007354.1 surface antigen msp4 1168235 3617754 Ecaj_0833 Ehrlichia canis str. Jake surface antigen msp4 YP_303462.1 1167372 D 269484 CDS YP_303463.1 73667447 3617755 complement(1168714..1171062) 1 NC_007354.1 hypothetical protein 1171062 3617755 Ecaj_0834 Ehrlichia canis str. Jake hypothetical protein YP_303463.1 1168714 R 269484 CDS YP_303464.1 73667448 3617756 complement(1171878..1175681) 1 NC_007354.1 hypothetical protein 1175681 3617756 Ecaj_0835 Ehrlichia canis str. Jake hypothetical protein YP_303464.1 1171878 R 269484 CDS YP_303465.1 73667449 3617757 complement(1176292..1176552) 1 NC_007354.1 hypothetical protein 1176552 3617757 Ecaj_0836 Ehrlichia canis str. Jake hypothetical protein YP_303465.1 1176292 R 269484 CDS YP_303466.1 73667450 3617758 complement(1177587..1178624) 1 NC_007354.1 hypothetical protein 1178624 3617758 Ecaj_0837 Ehrlichia canis str. Jake hypothetical protein YP_303466.1 1177587 R 269484 CDS YP_303467.1 73667451 3617759 complement(1178924..1183456) 1 NC_007354.1 hypothetical protein 1183456 3617759 Ecaj_0838 Ehrlichia canis str. Jake hypothetical protein YP_303467.1 1178924 R 269484 CDS YP_303468.1 73667452 3617760 complement(1184275..1186650) 1 NC_007354.1 type IV secretion system protein VirB5 1186650 3617760 Ecaj_0839 Ehrlichia canis str. Jake type IV secretion system protein VirB5 YP_303468.1 1184275 R 269484 CDS YP_303469.1 73667453 3617761 complement(1187439..1187801) 1 NC_007354.1 hypothetical protein 1187801 3617761 Ecaj_0840 Ehrlichia canis str. Jake hypothetical protein YP_303469.1 1187439 R 269484 CDS YP_303470.1 73667454 3617762 complement(1187873..1188238) 1 NC_007354.1 hypothetical protein 1188238 3617762 Ecaj_0841 Ehrlichia canis str. Jake hypothetical protein YP_303470.1 1187873 R 269484 CDS YP_303471.1 73667455 3617763 complement(1189755..1190132) 1 NC_007354.1 hypothetical protein 1190132 3617763 Ecaj_0842 Ehrlichia canis str. Jake hypothetical protein YP_303471.1 1189755 R 269484 CDS YP_303472.1 73667456 3617764 1190954..1192021 1 NC_007354.1 HflK protein 1192021 3617764 Ecaj_0843 Ehrlichia canis str. Jake HflK protein YP_303472.1 1190954 D 269484 CDS YP_303473.1 73667457 3617765 1192026..1192898 1 NC_007354.1 hypothetical protein 1192898 3617765 Ecaj_0844 Ehrlichia canis str. Jake hypothetical protein YP_303473.1 1192026 D 269484 CDS YP_303474.1 73667458 3617766 1192902..1194317 1 NC_007354.1 peptidase S1 1194317 3617766 Ecaj_0845 Ehrlichia canis str. Jake peptidase S1 YP_303474.1 1192902 D 269484 CDS YP_303475.1 73667459 3618237 1194319..1194900 1 NC_007354.1 hypothetical protein 1194900 3618237 Ecaj_0846 Ehrlichia canis str. Jake hypothetical protein YP_303475.1 1194319 D 269484 CDS YP_303476.1 73667460 3618238 1194907..1195587 1 NC_007354.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1195587 rnc 3618238 rnc Ehrlichia canis str. Jake ribonuclease III YP_303476.1 1194907 D 269484 CDS YP_303477.1 73667461 3618239 1195584..1196108 1 NC_007354.1 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 1196108 3618239 Ecaj_0848 Ehrlichia canis str. Jake cytochrome C oxidase assembly protein YP_303477.1 1195584 D 269484 CDS YP_303478.1 73667462 3618240 1196511..1197827 1 NC_007354.1 insulinase-like:peptidase M16, C-terminal 1197827 3618240 Ecaj_0849 Ehrlichia canis str. Jake insulinase-like:peptidase M16, C-terminal YP_303478.1 1196511 D 269484 CDS YP_303479.1 73667463 3618241 1197830..1199185 1 NC_007354.1 insulinase-like:peptidase M16, C-terminal 1199185 3618241 Ecaj_0850 Ehrlichia canis str. Jake insulinase-like:peptidase M16, C-terminal YP_303479.1 1197830 D 269484 CDS YP_303480.1 73667464 3618242 1199692..1200369 1 NC_007354.1 hypothetical protein 1200369 3618242 Ecaj_0851 Ehrlichia canis str. Jake hypothetical protein YP_303480.1 1199692 D 269484 CDS YP_303481.1 73667465 3618243 complement(1200452..1200913) 1 NC_007354.1 signal peptidase II 1200913 3618243 Ecaj_0852 Ehrlichia canis str. Jake signal peptidase II YP_303481.1 1200452 R 269484 CDS YP_303482.1 73667466 3618244 complement(1200913..1201830) 1 NC_007354.1 FMN adenylyltransferase / riboflavin kinase 1201830 3618244 Ecaj_0853 Ehrlichia canis str. Jake FMN adenylyltransferase / riboflavin kinase YP_303482.1 1200913 R 269484 CDS YP_303483.1 73667467 3618245 1201902..1202147 1 NC_007354.1 glutaredoxin 1202147 3618245 Ecaj_0854 Ehrlichia canis str. Jake glutaredoxin YP_303483.1 1201902 D 269484 CDS YP_303484.1 73667468 3618246 complement(1203071..1203913) 1 NC_007354.1 modification methylase HemK 1203913 3618246 Ecaj_0855 Ehrlichia canis str. Jake modification methylase HemK YP_303484.1 1203071 R 269484 CDS YP_303485.1 73667469 3618247 complement(1203920..1204720) 1 NC_007354.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1204720 3618247 Ecaj_0856 Ehrlichia canis str. Jake methionine aminopeptidase YP_303485.1 1203920 R 269484 CDS YP_303486.1 73667470 3618248 complement(1205663..1206865) 1 NC_007354.1 2-oxoglutarate dehydrogenase E2 component 1206865 3618248 Ecaj_0857 Ehrlichia canis str. Jake 2-oxoglutarate dehydrogenase E2 component YP_303486.1 1205663 R 269484 CDS YP_303487.1 73667471 3618249 complement(1207686..1208204) 1 NC_007354.1 hexapaptide repeat-containing transferase 1208204 3618249 Ecaj_0858 Ehrlichia canis str. Jake hexapaptide repeat-containing transferase YP_303487.1 1207686 R 269484 CDS YP_303488.1 73667472 3618250 1208489..1209640 1 NC_007354.1 serine-type D-Ala-D-Ala carboxypeptidase 1209640 3618250 Ecaj_0859 Ehrlichia canis str. Jake serine-type D-Ala-D-Ala carboxypeptidase YP_303488.1 1208489 D 269484 CDS YP_303489.1 73667473 3618251 complement(1210258..1211487) 1 NC_007354.1 cytochrome c biogenesis protein, transmembrane region 1211487 3618251 Ecaj_0860 Ehrlichia canis str. Jake cytochrome c biogenesis protein, transmembrane region YP_303489.1 1210258 R 269484 CDS YP_303490.1 73667474 3618252 complement(1211765..1212046) 1 NC_007354.1 hypothetical protein 1212046 3618252 Ecaj_0861 Ehrlichia canis str. Jake hypothetical protein YP_303490.1 1211765 R 269484 CDS YP_303491.1 73667475 3618253 1212163..1213305 1 NC_007354.1 peptidase RseP 1213305 3618253 Ecaj_0862 Ehrlichia canis str. Jake peptidase RseP YP_303491.1 1212163 D 269484 CDS YP_303492.1 73667476 3618254 1213310..1215619 1 NC_007354.1 surface antigen (D15):surface antigen variable number 1215619 3618254 Ecaj_0863 Ehrlichia canis str. Jake surface antigen (D15):surface antigen variable number YP_303492.1 1213310 D 269484 CDS YP_303493.1 73667477 3618255 1215632..1216180 1 NC_007354.1 hypothetical protein 1216180 3618255 Ecaj_0864 Ehrlichia canis str. Jake hypothetical protein YP_303493.1 1215632 D 269484 CDS YP_303494.1 73667478 3618417 1216202..1216648 1 NC_007354.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1216648 fabZ 3618417 fabZ Ehrlichia canis str. Jake (3R)-hydroxymyristoyl-ACP dehydratase YP_303494.1 1216202 D 269484 CDS YP_303495.1 73667479 3618418 1216681..1218195 1 NC_007354.1 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 1218195 3618418 Ecaj_0866 Ehrlichia canis str. Jake IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase YP_303495.1 1216681 D 269484 CDS YP_303496.1 73667480 3618419 complement(1219155..1219712) 1 NC_007354.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1219712 3618419 Ecaj_0867 Ehrlichia canis str. Jake CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_303496.1 1219155 R 269484 CDS YP_303497.1 73667481 3618420 1220004..1221314 1 NC_007354.1 cytochrome c oxidase subunit I 1221314 3618420 Ecaj_0868 Ehrlichia canis str. Jake cytochrome c oxidase subunit I YP_303497.1 1220004 D 269484 CDS YP_303498.1 73667482 3618421 complement(1222053..1222679) 1 NC_007354.1 hypothetical protein 1222679 3618421 Ecaj_0869 Ehrlichia canis str. Jake hypothetical protein YP_303498.1 1222053 R 269484 CDS YP_303499.1 73667483 3618422 1223010..1224917 1 NC_007354.1 pentapeptide repeat-containing protein 1224917 3618422 Ecaj_0870 Ehrlichia canis str. Jake pentapeptide repeat-containing protein YP_303499.1 1223010 D 269484 CDS YP_303500.1 73667484 3618423 complement(1225524..1226783) 1 NC_007354.1 glycerol-1-phosphate dehydrogenase 1226783 3618423 Ecaj_0871 Ehrlichia canis str. Jake glycerol-1-phosphate dehydrogenase YP_303500.1 1225524 R 269484 CDS YP_303501.1 73667485 3618424 1227219..1227950 1 NC_007354.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1227950 3618424 Ecaj_0872 Ehrlichia canis str. Jake F0F1 ATP synthase subunit A YP_303501.1 1227219 D 269484 CDS YP_303502.1 73667486 3618425 1228698..1228919 1 NC_007354.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1228919 3618425 Ecaj_0873 Ehrlichia canis str. Jake F0F1 ATP synthase subunit C YP_303502.1 1228698 D 269484 CDS YP_303503.1 73667487 3618426 1228928..1229431 1 NC_007354.1 H+-transporting two-sector ATPase subunit B/B' 1229431 3618426 Ecaj_0874 Ehrlichia canis str. Jake H+-transporting two-sector ATPase subunit B/B' YP_303503.1 1228928 D 269484 CDS YP_303504.1 73667488 3618427 1229428..1229913 1 NC_007354.1 hypothetical protein 1229913 3618427 Ecaj_0875 Ehrlichia canis str. Jake hypothetical protein YP_303504.1 1229428 D 269484 CDS YP_303505.1 73667489 3618428 complement(1229910..1231145) 1 NC_007354.1 cell division protein FtsA 1231145 3618428 Ecaj_0876 Ehrlichia canis str. Jake cell division protein FtsA YP_303505.1 1229910 R 269484 CDS YP_303506.1 73667490 3618429 complement(1231423..1232874) 1 NC_007354.1 cation transporter 1232874 3618429 Ecaj_0877 Ehrlichia canis str. Jake cation transporter YP_303506.1 1231423 R 269484 CDS YP_303507.1 73667491 3618431 1233844..1235145 1 NC_007354.1 cell cycle protein MesJ 1235145 3618431 Ecaj_0878 Ehrlichia canis str. Jake cell cycle protein MesJ YP_303507.1 1233844 D 269484 CDS YP_303508.1 73667492 3618432 1235142..1236977 1 NC_007354.1 FtsH peptidase 1236977 3618432 Ecaj_0879 Ehrlichia canis str. Jake FtsH peptidase YP_303508.1 1235142 D 269484 CDS YP_303509.1 73667493 3618433 complement(1238731..1239516) 1 NC_007354.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1239516 3618433 Ecaj_0880 Ehrlichia canis str. Jake prolipoprotein diacylglyceryl transferase YP_303509.1 1238731 R 269484 CDS YP_303510.1 73667494 3618434 1240088..1241005 1 NC_007354.1 hypothetical protein 1241005 3618434 Ecaj_0881 Ehrlichia canis str. Jake hypothetical protein YP_303510.1 1240088 D 269484 CDS YP_303511.1 73667495 3618435 complement(1241340..1242923) 1 NC_007354.1 hypothetical protein 1242923 3618435 Ecaj_0882 Ehrlichia canis str. Jake hypothetical protein YP_303511.1 1241340 R 269484 CDS YP_303512.1 73667496 3618526 complement(1243795..1243956) 1 NC_007354.1 hypothetical protein 1243956 3618526 Ecaj_0884 Ehrlichia canis str. Jake hypothetical protein YP_303512.1 1243795 R 269484 CDS YP_303513.1 73667497 3618527 complement(1243985..1245511) 1 NC_007354.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1245511 secD 3618527 secD Ehrlichia canis str. Jake preprotein translocase subunit SecD YP_303513.1 1243985 R 269484 CDS YP_303514.1 73667498 3618528 complement(1246329..1247111) 1 NC_007354.1 UBA/THIF-type NAD/FAD binding fold:MoeZ/MoeB 1247111 3618528 Ecaj_0885 Ehrlichia canis str. Jake UBA/THIF-type NAD/FAD binding fold:MoeZ/MoeB YP_303514.1 1246329 R 269484 CDS YP_303515.1 73667499 3618529 complement(1247115..1247711) 1 NC_007354.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1247711 pyrE 3618529 pyrE Ehrlichia canis str. Jake orotate phosphoribosyltransferase YP_303515.1 1247115 R 269484 CDS YP_303516.1 73667500 3618530 complement(1247738..1248811) 1 NC_007354.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1248811 recA 3618530 recA Ehrlichia canis str. Jake recombinase A YP_303516.1 1247738 R 269484 CDS YP_303517.1 73667501 3618531 complement(1249400..1250095) 1 NC_007354.1 dethiobiotin synthase 1250095 3618531 Ecaj_0888 Ehrlichia canis str. Jake dethiobiotin synthase YP_303517.1 1249400 R 269484 CDS YP_303518.1 73667502 3618532 1250171..1251103 1 NC_007354.1 signal recognition particle-docking protein FtsY 1251103 3618532 Ecaj_0889 Ehrlichia canis str. Jake signal recognition particle-docking protein FtsY YP_303518.1 1250171 D 269484 CDS YP_303519.1 73667503 3618533 complement(1251161..1252609) 1 NC_007354.1 catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 1252609 3618533 Ecaj_0890 Ehrlichia canis str. Jake isocitrate dehydrogenase YP_303519.1 1251161 R 269484 CDS YP_303520.1 73667504 3618534 1252905..1254659 1 NC_007354.1 RecJ exonuclease 1254659 3618534 Ecaj_0891 Ehrlichia canis str. Jake RecJ exonuclease YP_303520.1 1252905 D 269484 CDS YP_303521.1 73667505 3618535 1256195..1257385 1 NC_007354.1 polynucleotide adenylyl transferase 1257385 3618535 Ecaj_0892 Ehrlichia canis str. Jake polynucleotide adenylyl transferase YP_303521.1 1256195 D 269484 CDS YP_303522.1 73667506 3618536 complement(1257837..1258274) 1 NC_007354.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1258274 ndk 3618536 ndk Ehrlichia canis str. Jake nucleoside diphosphate kinase YP_303522.1 1257837 R 269484 CDS YP_303523.1 73667507 3618537 1258507..1259154 1 NC_007354.1 transcriptional regulator 1259154 3618537 Ecaj_0894 Ehrlichia canis str. Jake transcriptional regulator YP_303523.1 1258507 D 269484 CDS YP_303524.1 73667508 3618538 1259382..1260272 1 NC_007354.1 surface antigen msp4 1260272 3618538 Ecaj_0895 Ehrlichia canis str. Jake surface antigen msp4 YP_303524.1 1259382 D 269484 CDS YP_303525.1 73667509 3618392 1261030..1261857 1 NC_007354.1 surface antigen msp4 1261857 3618392 Ecaj_0896 Ehrlichia canis str. Jake surface antigen msp4 YP_303525.1 1261030 D 269484 CDS YP_303526.1 73667510 3618393 1261964..1262410 1 NC_007354.1 hypothetical protein 1262410 3618393 Ecaj_0897 Ehrlichia canis str. Jake hypothetical protein YP_303526.1 1261964 D 269484 CDS YP_303527.1 73667511 3618394 1262421..1263371 1 NC_007354.1 surface antigen msp4 1263371 3618394 Ecaj_0898 Ehrlichia canis str. Jake surface antigen msp4 YP_303527.1 1262421 D 269484 CDS YP_303528.1 73667512 3618395 1263387..1264238 1 NC_007354.1 surface antigen msp4 1264238 3618395 Ecaj_0899 Ehrlichia canis str. Jake surface antigen msp4 YP_303528.1 1263387 D 269484 CDS YP_303529.1 73667513 3618396 1264255..1265049 1 NC_007354.1 surface antigen msp4 1265049 3618396 Ecaj_0900 Ehrlichia canis str. Jake surface antigen msp4 YP_303529.1 1264255 D 269484 CDS YP_303530.1 73667514 3618397 1265064..1265933 1 NC_007354.1 surface antigen msp4 1265933 3618397 Ecaj_0901 Ehrlichia canis str. Jake surface antigen msp4 YP_303530.1 1265064 D 269484 CDS YP_303531.1 73667515 3618455 1265958..1266794 1 NC_007354.1 surface antigen msp4 1266794 3618455 Ecaj_0902 Ehrlichia canis str. Jake surface antigen msp4 YP_303531.1 1265958 D 269484 CDS YP_303532.1 73667516 3618456 1266805..1267362 1 NC_007354.1 hypothetical protein 1267362 3618456 Ecaj_0903 Ehrlichia canis str. Jake hypothetical protein YP_303532.1 1266805 D 269484 CDS YP_303533.1 73667517 3618457 1267355..1268224 1 NC_007354.1 surface antigen msp4 1268224 3618457 Ecaj_0904 Ehrlichia canis str. Jake surface antigen msp4 YP_303533.1 1267355 D 269484 CDS YP_303534.1 73667518 3618458 1268233..1269072 1 NC_007354.1 surface antigen msp4 1269072 3618458 Ecaj_0905 Ehrlichia canis str. Jake surface antigen msp4 YP_303534.1 1268233 D 269484 CDS YP_303535.1 73667519 3618459 1269082..1269927 1 NC_007354.1 surface antigen msp4 1269927 3618459 Ecaj_0906 Ehrlichia canis str. Jake surface antigen msp4 YP_303535.1 1269082 D 269484 CDS YP_303536.1 73667520 3618460 1269950..1270849 1 NC_007354.1 surface antigen msp4 1270849 3618460 Ecaj_0907 Ehrlichia canis str. Jake surface antigen msp4 YP_303536.1 1269950 D 269484 CDS YP_303537.1 73667521 3618461 1270873..1271751 1 NC_007354.1 surface antigen msp4 1271751 3618461 Ecaj_0908 Ehrlichia canis str. Jake surface antigen msp4 YP_303537.1 1270873 D 269484 CDS YP_303538.1 73667522 3618462 1271764..1272648 1 NC_007354.1 surface antigen msp4 1272648 3618462 Ecaj_0909 Ehrlichia canis str. Jake surface antigen msp4 YP_303538.1 1271764 D 269484 CDS YP_303539.1 73667523 3618463 1272672..1273553 1 NC_007354.1 surface antigen msp4 1273553 3618463 Ecaj_0910 Ehrlichia canis str. Jake surface antigen msp4 YP_303539.1 1272672 D 269484 CDS YP_303540.1 73667524 3618464 1274101..1274943 1 NC_007354.1 surface antigen msp4 1274943 3618464 Ecaj_0911 Ehrlichia canis str. Jake surface antigen msp4 YP_303540.1 1274101 D 269484 CDS YP_303541.1 73667525 3618465 1275271..1276101 1 NC_007354.1 surface antigen msp4 1276101 3618465 Ecaj_0912 Ehrlichia canis str. Jake surface antigen msp4 YP_303541.1 1275271 D 269484 CDS YP_303542.1 73667526 3618466 1276312..1277175 1 NC_007354.1 surface antigen msp4 1277175 3618466 Ecaj_0913 Ehrlichia canis str. Jake surface antigen msp4 YP_303542.1 1276312 D 269484 CDS YP_303543.1 73667527 3618467 1277472..1278323 1 NC_007354.1 surface antigen msp4 1278323 3618467 Ecaj_0914 Ehrlichia canis str. Jake surface antigen msp4 YP_303543.1 1277472 D 269484 CDS YP_303544.1 73667528 3618468 1278666..1279508 1 NC_007354.1 surface antigen msp4 1279508 3618468 Ecaj_0915 Ehrlichia canis str. Jake surface antigen msp4 YP_303544.1 1278666 D 269484 CDS YP_303545.1 73667529 3618469 1279849..1280685 1 NC_007354.1 surface antigen msp4 1280685 3618469 Ecaj_0916 Ehrlichia canis str. Jake surface antigen msp4 YP_303545.1 1279849 D 269484 CDS YP_303546.1 73667530 3618470 1281037..1281903 1 NC_007354.1 surface antigen msp4 1281903 3618470 Ecaj_0917 Ehrlichia canis str. Jake surface antigen msp4 YP_303546.1 1281037 D 269484 CDS YP_303547.1 73667531 3618471 complement(1282530..1283357) 1 NC_007354.1 major outer membrane protein P30- 20;surface antigen 1283357 3618471 Ecaj_0918 Ehrlichia canis str. Jake major outer membrane protein P30- 20;surface antigen YP_303547.1 1282530 R 269484 CDS YP_303548.1 73667532 3618472 1284854..1285216 1 NC_007354.1 hypothetical protein 1285216 3618472 Ecaj_0919 Ehrlichia canis str. Jake hypothetical protein YP_303548.1 1284854 D 269484 CDS YP_303549.1 73667533 3618473 1285588..1286136 1 NC_007354.1 hypothetical protein 1286136 3618473 Ecaj_0920 Ehrlichia canis str. Jake hypothetical protein YP_303549.1 1285588 D 269484 CDS YP_303550.1 73667534 3618474 1286475..1289063 1 NC_007354.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1289063 secA 3618474 secA Ehrlichia canis str. Jake preprotein translocase subunit SecA YP_303550.1 1286475 D 269484 CDS YP_303551.1 73667535 3617854 complement(1289739..1290140) 1 NC_007354.1 hypothetical protein 1290140 3617854 Ecaj_0922 Ehrlichia canis str. Jake hypothetical protein YP_303551.1 1289739 R 269484 CDS YP_303552.1 73667536 3617855 complement(1290358..1290912) 1 NC_007354.1 hypothetical protein 1290912 3617855 Ecaj_0923 Ehrlichia canis str. Jake hypothetical protein YP_303552.1 1290358 R 269484 CDS YP_303553.1 73667537 3617856 complement(1291213..1291647) 1 NC_007354.1 hypothetical protein 1291647 3617856 Ecaj_0924 Ehrlichia canis str. Jake hypothetical protein YP_303553.1 1291213 R 269484 CDS YP_303554.1 73667538 3617857 1292028..1293290 1 NC_007354.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1293290 3617857 Ecaj_0925 Ehrlichia canis str. Jake cell division protein FtsZ YP_303554.1 1292028 D 269484 CDS YP_303555.1 73667539 3617858 1293297..1293704 1 NC_007354.1 hypothetical protein 1293704 3617858 Ecaj_0926 Ehrlichia canis str. Jake hypothetical protein YP_303555.1 1293297 D 269484 CDS YP_303556.1 73667540 3617859 1293701..1294165 1 NC_007354.1 hypothetical protein 1294165 3617859 Ecaj_0927 Ehrlichia canis str. Jake hypothetical protein YP_303556.1 1293701 D 269484 CDS YP_303557.1 73667541 3617860 1294544..1295311 1 NC_007354.1 chromosome segregation ATPase 1295311 3617860 Ecaj_0928 Ehrlichia canis str. Jake chromosome segregation ATPase YP_303557.1 1294544 D 269484 CDS YP_303558.1 73667542 3617861 1295324..1296175 1 NC_007354.1 chromosome segregation DNA-binding protein 1296175 3617861 Ecaj_0929 Ehrlichia canis str. Jake chromosome segregation DNA-binding protein YP_303558.1 1295324 D 269484 CDS YP_303559.1 73667543 3617862 1296288..1296809 1 NC_007354.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1296809 rimM 3617862 rimM Ehrlichia canis str. Jake 16S rRNA-processing protein RimM YP_303559.1 1296288 D 269484 CDS YP_303560.1 73667544 3617863 1296799..1297506 1 NC_007354.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1297506 trmD 3617863 trmD Ehrlichia canis str. Jake tRNA (guanine-N(1)-)-methyltransferase YP_303560.1 1296799 D 269484 CDS YP_303561.1 73667545 3617864 1297499..1297876 1 NC_007354.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1297876 rplS 3617864 rplS Ehrlichia canis str. Jake 50S ribosomal protein L19 YP_303561.1 1297499 D 269484 CDS YP_303562.1 73667546 3617865 complement(1298118..1298600) 1 NC_007354.1 competence/damage-inducible protein cinA 1298600 3617865 Ecaj_0933 Ehrlichia canis str. Jake competence/damage-inducible protein cinA YP_303562.1 1298118 R 269484 CDS YP_303563.1 73667547 3617866 1298952..1300853 1 NC_007354.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1300853 thrS 3617866 thrS Ehrlichia canis str. Jake threonyl-tRNA synthetase YP_303563.1 1298952 D 269484 CDS YP_303564.1 73667548 3617867 1300921..1301400 1 NC_007354.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1301400 3617867 Ecaj_0935 Ehrlichia canis str. Jake translation initiation factor IF-3 YP_303564.1 1300921 D 269484 CDS YP_303565.1 73667549 3617868 complement(1304068..1304535) 1 NC_007354.1 hypothetical protein 1304535 3617868 Ecaj_0936 Ehrlichia canis str. Jake hypothetical protein YP_303565.1 1304068 R 269484 CDS YP_303566.1 73667550 3617869 complement(1304561..1305265) 1 NC_007354.1 hypothetical protein 1305265 3617869 Ecaj_0937 Ehrlichia canis str. Jake hypothetical protein YP_303566.1 1304561 R 269484 CDS YP_303567.1 73667551 3617870 complement(1305339..1306316) 1 NC_007354.1 hypothetical protein 1306316 3617870 Ecaj_0938 Ehrlichia canis str. Jake hypothetical protein YP_303567.1 1305339 R 269484 CDS YP_303568.1 73667552 3617871 1306525..1307526 1 NC_007354.1 glyceraldehyde-3-phosphate dehydrogenase 1307526 3617871 Ecaj_0939 Ehrlichia canis str. Jake glyceraldehyde-3-phosphate dehydrogenase YP_303568.1 1306525 D 269484 CDS YP_303569.1 73667553 3617872 complement(1307857..1308516) 1 NC_007354.1 isoprenoid biosynthesis protein with amidotransferase-like domain 1308516 3617872 Ecaj_0940 Ehrlichia canis str. Jake isoprenoid biosynthesis protein with amidotransferase-like domain YP_303569.1 1307857 R 269484 CDS YP_303570.1 73667554 3617572 1308635..1309441 1 NC_007354.1 pyrroline-5-carboxylate reductase 1309441 3617572 Ecaj_0941 Ehrlichia canis str. Jake pyrroline-5-carboxylate reductase YP_303570.1 1308635 D 269484 CDS YP_303571.1 73667555 3617574 1309631..1311106 1 NC_007354.1 DNA-directed DNA polymerase 1311106 3617574 Ecaj_0942 Ehrlichia canis str. Jake DNA-directed DNA polymerase YP_303571.1 1309631 D 269484 CDS YP_303572.1 73667556 3617575 1311121..1311426 1 NC_007354.1 hypothetical protein 1311426 3617575 Ecaj_0943 Ehrlichia canis str. Jake hypothetical protein YP_303572.1 1311121 D 269484 CDS YP_303573.1 73667557 3617576 1311438..1312448 1 NC_007354.1 aspartate semialdehyde dehydrogenase 1312448 3617576 Ecaj_0944 Ehrlichia canis str. Jake aspartate semialdehyde dehydrogenase YP_303573.1 1311438 D 269484 CDS YP_303574.1 73667558 3617577 complement(1313490..1314671) 1 NC_007354.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1314671 3617577 Ecaj_0945 Ehrlichia canis str. Jake S-adenosylmethionine synthetase YP_303574.1 1313490 R 269484 CDS