-- dump date 20140619_065658 -- class Genbank::CDS -- table cds_note -- id note YP_001531351.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001531352.1 PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase KEGG: sit:TM1040_2823 glutamate synthase (ferredoxin), involved in nitrogen metabolism PATH: rn00910 YP_001531354.1 PFAM: conserved hypothetical protein KEGG: sil:SPO3342 decarboxylase family protein, Homologous Superfamily (CATH Code: 3.40.50.80), Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module YP_001531355.1 interPro: short signalpeptide N-terminal, bad swissprot hit to Sterol 3-beta-glucosyltransferase from Candida albicans and bad Ref NP hit to 4-alpha-glucanotransferase from Fusobacterium nucleatum subsp. nucleatum ATCC 25586 YP_001531356.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001531358.1 bad swissprot to LPS-assembly protein precursor (Organic solvent tolerance protein) from Pseudomonas aeruginosa UCBPP-PA14 and bad ref ZP hit to putative chemotaxis protein from Erythrobacter sp. NAP1, short signalpeptide and transmembranedomain, conserved domain: Guanylate kinase/L-type calcium channel region (Active enzymes catalyze ATP-dependent phosphorylation of GMP to GDP) YP_001531359.1 PFAM: Cold-shock protein DNA-binding SMART: Cold shock protein KEGG: rde:RD1_1402 cold shock protein CspA-related protein, putative YP_001531360.1 PFAM: protein of unknown function DUF305 KEGG: psa:PST_3374 hypothetical protein, conserved in bacteria YP_001531361.1 KEGG: rsq:Rsph17025_0047 hypothetical protein, bad swissprot hit to Multiple PDZ domain protein from rattus norvegicus involved in cell junction/cell projection; Immunoglobulin V-Type, subgroup domain (Eukaryota) from T cell surface glycoproteins, junction adhesion molecules , cell surface presentation? YP_001531362.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001531363.1 PFAM: GCN5-related N-acetyltransferase KEGG: rsh:Rsph17029_2788 GCN5-related N-acetyltransferase YP_001531364.1 KEGG: sil:SPO3331 hypothetical protein, Uncharacterized protein conserved in bacteria COG3222, bad swissprot hit to Carboxylesterase bioH (Biotin synthesis protein bioH) from Escherichia coli, Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic acid into pimeloyl-CoA YP_001531365.1 KEGG: sit:TM1040_2994 ribonuclease R TIGRFAM: VacB and RNase II family 3-5 exoribonuclease; ribonuclease R PFAM: ribonuclease II; RNA binding S1 domain protein, high sw hit to Ribonuclease R (RNase R) (VacB protein homolog) from Haemophilus influenzae YP_001531366.1 TIGRFAM: lytic murein transglycosylase PFAM: Peptidoglycan-binding domain 1 protein KEGG: rde:RD1_0181 transglycosylase, putative, good sw hit to Membrane-bound lytic murein transglycosylase B precursor from E. coli YP_001531367.1 KEGG: jan:Jann_0593 hypothetical protein, one single bad swissprot hit to ATP synthase protein 8 (ATPase subunit 8) from mitochondrion Artemia franciscana, short signalpeptide and transmembrane domains, uDENN Domain: found in a variety of signalling proteins, is a good candidate for a GTP/GDP exchange activity YP_001531368.1 PFAM: multicopper oxidase type 2 KEGG: hch:HCH_03584 putative multicopper oxidases, diverse cupredoxin and multicopper oxidase 1-3 domains, bad swissprot hit to Blue copper oxidase cueO precursor (Copper efflux oxidase) from Escherichia coli O157:H7, Copper resistance protein A (copA) from a plasmid in Pseudomonas syringae. This protein seems to be involved in the resistance of the microbial host to copper YP_001531369.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein KEGG: rde:RD1_2707 GTP-binding protein TypA, putative, high swissprot hit to GTP-binding protein TypA/BipA homolog from Helicobacter pylori, diverse translation and elongation factor domains YP_001531370.1 KEGG: sil:SPO3454 hypothetical protein, no significant swissprot hit, next good Ref YP hit to putative transcriptional regulator, CadC from Silicibacter sp. TM1040, three domains to trans_reg_C, Effector domain of response regulator, CadC, DNA-binding winged-HTH domains and OmpR, Response regulators consisting of a CheY-like receiver domain; CadC YP_001531371.1 KEGG: rsp:RSP_6002 hypothetical protein, one single transmembrane domain YP_001531372.1 no swissprot hit, next ref ZP hit to hypothetical protein RB2150_13021 from Rhodobacterales bacterium HTCC2150, short signalpeptide and two transmembrane regions, NO hit to Sodium/hydrogen exchanger family Pfam00999 YP_001531373.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001531374.1 PFAM: DNA methylase N-4/N-6 domain protein KEGG: rsq:Rsph17025_0066 DNA methylase N-4/N-6 domain protein, high swissprot hit to Modification methylase CcrMI (Adenine-specific methyltransferase CcrMI from Caulobacter vibrioides (Caulobacter crescentus) YP_001531375.1 KEGG: abo:ABO_0664 hypothetical protein, Cupin, RmlC-type domain, best swissprot hit to Transcriptional activator chrR from Rhodobacter sphaeroides 2.4.1 and high similarity to Predicted transcription negative regulator (refZP hit) from Roseovarius sp. 217 YP_001531376.1 KEGG: jan:Jann_0393 NAD-dependent epimerase/dehydratase, best swissprot hit to Flavin reductase (FR) (NADPH-dependent diaphorase) from Mus musculus YP_001531377.1 PFAM: fatty acid desaturase KEGG: sit:TM1040_2646 alkane-1 monooxygenase, good swissprot hit to Alkane 1-monooxygenase (Alkane omega-hydroxylase) from Pseudomonas oleovorans, also fatty acid desaturase typ 1 domain Pfam00487 YP_001531378.1 TIGRFAM: A/G-specific adenine glycosylase PFAM: helix-hairpin-helix motif; HhH-GPD family protein KEGG: sit:TM1040_2645 A/G-specific adenine glycosylase, swissprot to A/G-specific adenine glycosylase from Escherichia coli YP_001531379.1 PFAM: protein of unknown function DUF1159 KEGG: sit:TM1040_2644 protein of unknown function DUF1159 YP_001531380.1 KEGG: rde:RD1_0295 thiol-disulfide oxidoreductase D, putative, swissprot hit to Putative protein-disulfide oxidoreductase RBE_1288 precursor from Rickettsia bellii RML369-C, conserved domains: dsbA: a monomeric thiol disulfide oxidoreductase protein and dsbG: Protein-disulfide isomerase YP_001531381.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001531382.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein KEGG: jan:Jann_0400 three-deoxy-D-manno-octulosonic-acid transferase-like YP_001531383.1 PFAM: protein of unknown function DUF343 KEGG: sit:TM1040_0056 protein of unknown function DUF343, DUF343 domain: Trm112p-like protein, The function of this family is uncertain. The bacterial members are about 60-70 amino acids in length. The C terminus contains the strongest conservation. Trm112p is required for tRNA methylation n S. cerevisiae and is found in complexes with 2 tRNA methylases (TRM9 and TRM11) also with putative methyltransferase YDR140W. YP_001531384.1 PFAM: peptidase S16 lon domain protein KEGG: rsq:Rsph17025_2895 peptidase S16, lon domain protein, swissprot hit to ATP-dependent protease La 2 from Myxococcus xanthus, COG2802: Uncharacterized protein, similar to the N-terminal domain of Lon protease and LON-domains YP_001531385.1 PFAM: Thioredoxin domain KEGG: rsp:RSP_1489 protein containing thioredoxin domain, swissprot hit to Thioredoxin (TRX) from Pasteurella multocida YP_001531386.1 TIGRFAM: exodeoxyribonuclease III Xth PFAM: Endonuclease/exonuclease/phosphatase KEGG: sit:TM1040_0053 exodeoxyribonuclease III, best swissprot hit to Exodeoxyribonuclease III (Exonuclease III) from Escherichia coli YP_001531387.1 unsure, bad GC frame plot, no significant Ref hits; some kind of LPxTG anchor domains detected by TIGRfam, but unconvincing; some leucine repeats at C-terminal YP_001531388.1 PFAM: response regulator receiver; transcriptional regulator domain protein KEGG: jan:Jann_0417 two component transcriptional regulator, winged helix family, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, best swissprot hit to Transcriptional regulatory protein yycF from Bacillus subtilis; winged helix family YP_001531389.1 PFAM: GTP cyclohydrolase II KEGG: sil:SPO3427 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II YP_001531390.1 PFAM: protein of unknown function DUF1330 KEGG: sit:TM1040_1707 protein of unknown function DUF1330, no significant swissprot hit, best ref ZP hit to hypothetical protein OM2255_07195 from alpha proteobacterium HTCC2255 YP_001531391.1 KEGG: rde:RD1_0044 hypothetical protein, no significant swissprot hit, conserved domain found in several roseobacter function unknown YP_001531392.1 PFAM: alanine racemase domain protein KEGG: jan:Jann_0414 protein of unknown function UPF0001, swissprot hit to UPF0001 protein yggS from E. coli O6 related to PLP dependent enzymes class III YP_001531393.1 swissprot hit to porin from Rhodobacter capsulatus and high ref ZP hit to putative porin from D. shibae DshiDRAFT_2133 which doesnt exist in the finished sequence and to outer membrane porin, putative from Roseobacter sp. CCS2, also conserved domain to porin, Gram-negative type (interPro); Gram-negative type YP_001531394.1 KEGG: rsq:Rsph17025_3134 hypothetical protein YP_001531395.1 bad BLAST hits to hypothetical proteins, no significant swissprot hit, no domains detected by TIGRfam (no UspA domain) YP_001531396.1 no Interpro hits reported, unsure, bad GC frame plot, bad ref ZP hits to hypothetical protein ROS217_08770 from Roseovarius sp. 217 YP_001531397.1 no Interpro hits reported, unsure, bad GC frame plot, bad ref XP hits to hypothetical protein MGG_12456 from Magnaporthe grisea 70-15 (Fungi) YP_001531398.1 KEGG: rpc:RPC_0725 putative transposase, good ref ZP hit to possible transposase from Roseovarius sp. 217, InterPro:several Zinc finger domains (DNA binding?) YP_001531399.1 KEGG: har:HEAR2212 hypothetical protein, no InterPro hit, no good swissprot hit, Ref ZP hit to hypothetical protein ROS217_08790 fromRoseovarius sp. 217, next Ref ZP hit to GMP synthase, PP-ATPase domain/subunit from Magnetospirillum magnetotacticum MS-1 YP_001531400.1 PFAM: protein of unknown function DUF955 KEGG: mag:amb3753 predicted Zn peptidase, no significant swissprot hit, good ref Yp hit to Predicted Zn peptidase from Magnetospirillum magneticum AMB-1, DUF955 domain shows similarity to Peptidase_M48 YP_001531401.1 no significant BLAST hits, short signal peptide and two transmembrane regions, bad GC frame plot YP_001531402.1 no hits reported for InterPro Scan, BLAST hits similar to several hypothetical proteins in Roseobacter strains, bad GC frame plot YP_001531403.1 PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase KEGG: sil:SPO3436 hypothetical protein, best ref ZP hit to hypothetical protein ISM_02290 from Roseovarius nubinhibens ISM: related to COG2081 Predicted flavoproteins, HI0933 like domain: This is a family of conserved hypothetical proteins that may include proteins with a dinucleotide-binding motif (Rossman fold), including oxidoreductases and dehydrogenases YP_001531404.1 PFAM: Glutathione S-transferase domain KEGG: pde:Pden_2769 glutathione S-transferase, N-terminal domain and C-terminal domain; Thioredoxin fold YP_001531405.1 KEGG: sit:TM1040_0043 DNA polymerase III, delta subunit YP_001531406.1 KEGG: rsq:Rsph17025_3136 hypothetical protein, best ref ZP hit to lipoprotein, putative from Sulfitobacter sp. NAS-14.1, no significant InterPro Scan hits YP_001531407.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001531408.1 PFAM: outer membrane lipoprotein carrier protein LolA KEGG: rsq:Rsph17025_2901 outer membrane lipoprotein carrier protein LolA YP_001531409.1 PFAM: cell divisionFtsK/SpoIIIE KEGG: rde:RD1_0033 cell division protein FtsK; very good swissprot hit to DNA translocase ftsK from Agrobacterium tumefaciens str. C58 YP_001531410.1 PFAM: aminotransferase class I and II KEGG: sil:SPO3417 aminotransferase, classes I and II; swissprot hit to Putative aminotransferase aatC from Sinorhizobium meliloti YP_001531411.1 PFAM: Amidase KEGG: rsq:Rsph17025_2898 amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; best swissprot hit to Glutamyl-tRNA(Gln) amidotransferase subunit A from Dehalococcoides ethenogenes 195 : function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity). YP_001531412.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family PFAM: monooxygenase FAD-binding KEGG: sil:SPO3419 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases COG0654; best swissprot hit to 2-octaprenyl-6-methoxyphenol hydroxylase from Escherichia coli K12 YP_001531413.1 PFAM: inositol monophosphatase KEGG: sil:SPO3443 inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; best BLAST hits to inositol monophosphatase family protein from Oceanicola batsensis HTCC2597 (refZP) and Inositol-1-monophosphatase (IMPase) from Sinorhizobium meliloti (Rhizobium meliloti) (swissprot) YP_001531414.1 PFAM: peptidase U62 modulator of DNA gyrase KEGG: sit:TM1040_2639 peptidase U62, modulator of DNA gyrase; COG0312 Predicted Zn-dependent proteases and their inactivated homologs; good swissprot hit to Protein pmbA (Protein tldE) from Escherichia coli K12 YP_001531415.1 KEGG: sil:SPO3441 hypothetical protein, no swissprot hit, ref hits to several hypothetical proteins in roseobacter strains YP_001531416.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein KEGG: sil:SPO3440 20-beta-hydroxysteroid dehydrogenase, putative, BLAST hits to several dehydrogenase proteins: swissprot hit to Uncharacterized oxidoreductase SSP1627 from Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 (Belongs to the short-chain dehydrogenases/reductases (SDR) family and ref hits to 20-beta-hydroxysteroid dehydrogenase, putative from Silicibacter pomeroyi DSS-3 YP_001531417.1 PFAM: Enoyl-CoA hydratase/isomerase KEGG: rsh:Rsph17029_2572 enoyl-CoA hydratase/isomerase; COG1024 Enoyl-CoA hydratase/carnithine racemase YP_001531418.1 KEGG: sil:SPO3414 lipoprotein, putative; Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do goose-type lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. YP_001531419.1 PFAM: Auxin Efflux Carrier; COG0679 Predicted permeases, good Ref ZP hit to auxin efflux carrier family protein fromSulfitobacter sp. EE-36, swissprot hit to Uncharacterized transporter MTH_1382 from Methanothermobacter thermautotrophicus str. Delta H YP_001531420.1 TIGRFAM: hemimethylated DNA binding protein PFAM: Hemimethylated DNA-binding region KEGG: sil:SPO3412 hypothetical protein, no swissprot YP_001531421.1 PFAM: gamma-glutamyltranspeptidase KEGG: sit:TM1040_0064 gamma-glutamyltransferase, good swissprot hit to Gamma-glutamyltranspeptidase precursor from Bacillus subtilis YP_001531422.1 KEGG: rde:RD1_0027 serine-protein kinase, putative; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); ATP-binding region is related to ATPase domains of histidine kinase; Anti-sigma-B factor YP_001531423.1 TIGRFAM: anti-anti-sigma factor PFAM: Sulfate transporter/antisigma-factor antagonist STAS KEGG: rsq:Rsph17025_2906 anti-sigma-factor antagonist, SpoIIAA domain: The establishment of differential gene expression in sporulating Bacillus subtilis involves four protein components one of which is SpoIIAA (). The four components regulate the sporulation sigma factor F. Early in sporulation, SpoIIAA is in the phosphorylated state (SpoIIAA-P), as a result YP_001531424.1 KEGG: jan:Jann_4050 acetyl-CoA C-acetyltransferase TIGRFAM: acetyl-CoA acetyltransferase PFAM: Thiolase; good swissprot hit to Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase) from Clostridium acetobutylicum; found domain accords to thiolase II YP_001531425.1 KEGG: rde:RD1_0777 hypothetical protein; bad BLAST hits, no swissprot: Calcium-binding EF-hand domain YP_001531426.1 KEGG: rsq:Rsph17025_3561 IstB domain protein ATP-binding protein; no IPR domain, best Blast hit to Integrase, catalytic region from Rhodobacter sphaeroides ATCC 17025; bad GC frame plot YP_001531427.1 no significant BLAST hits, unsure GC frame plot, IPR found small domain of intermediate filament from eukaryotes, integrated by Dshi_0076 possible integrase? YP_001531428.1 no significant BLAST hits, unsure GC frame plot, no InterPro Scan hits detected, but good RBS binding site AGGAT YP_001531429.1 PFAM: lipid A biosynthesis acyltransferase KEGG: sil:SPO1058 acyltransferase, HtrB family YP_001531430.1 PFAM: protein of unknown function DUF6 transmembrane KEGG: jan:Jann_0131 protein of unknown function DUF6, transmembrane; good hits to putative transporter, RhaT family, DMT superfamily from Loktanella vestfoldensis SKA53; also middle-rate swissprot hit to S-adenosylmethionine uptake transporter from Rickettsia typhi YP_001531431.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001531432.1 KEGG: rde:RD1_0227 hypothetical protein, small signalpeptide YP_001531433.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001531434.1 KEGG: bja:blr2987 hypothetical protein, uncharacterized conserved protein function unknown, transmembrane regions, signalpeptide YP_001531435.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001531436.1 PFAM: SOUL heme-binding protein KEGG: bra:BRADO5496 putative heme-binding protein, SOUL family, swissprot hit to Heme-binding-like protein At3g10130 chloroplast precursor from Arabidopsis thaliana YP_001531437.1 TIGRFAM: iojap-like protein PFAM: Iojap-related protein KEGG: sit:TM1040_2506 iojap-related protein; good ref ZP hit to iojap-related protein from Rhodobacterales bacterium HTCC2654 YP_001531438.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001531439.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001531440.1 PFAM: peptidase M23B KEGG: rsh:Rsph17029_2592 peptidase M23B YP_001531441.1 KEGG: rde:RD1_0333 carboxyl-terminal protease family protein, putative TIGRFAM: carboxyl-terminal protease PFAM: PDZ/DHR/GLGF domain protein; peptidase S41, high swissprot hit to Carboxy-terminal-processing protease precursor from Bartonella bacilliformis KC583; RBS site AGGAT YP_001531442.1 PFAM: NUDIX hydrolase KEGG: rde:RD1_0960 hydrolase, NUDIX family domain; good swissprot hit to Probable (di)nucleoside polyphosphate hydrolase from Silicibacter pomeroyi and Ap4A domain YP_001531443.1 no significant BLAST hit, small signalpeptide, bad GC frame plot, Dshi_0100 putative transposase YP_001531444.1 KEGG: rde:RD1_0345 hypothetical protein, domain of protease I prophage; no swissprot YP_001531445.1 KEGG: rde:RD1_0344 hypothetical protein, no swissprot, no IPR Scan result, COG4397 Mu-like prophage major head subunit gpT YP_001531446.1 unsure GC frame plot, no significant BLAST hits, no IPR Scan results YP_001531447.1 KEGG: rde:RD1_0343 hypothetical protein, no swissprot, no IPR results, DUF1018 domain: This family consists of several bacterial and phage proteins of unknown function. YP_001531448.1 no significant BLAST hit, unsure GC frame plot, no IPR scan result YP_001531449.1 KEGG: ecs:ECs4946 putative DNA transposition protein, bad BLAST hits, AAA ATPase domain (COG2842 Uncharacterized ATPase, putative transposase ) YP_001531450.1 KEGG: rde:RD1_0339 transposase, putative; swissprot hit to Transposase from Enterobacteria phage Mu; pfam02914 Mu_transposase YP_001531451.1 unsure GC frame plot, no significant BLAST hits, no IPR Scan result YP_001531452.1 KEGG: rde:RD1_0336 DNA polymerase III, alpha subunit TIGRFAM: DNA polymerase III, alpha subunit PFAM: DNA polymerase III alpha subunit SMART: phosphoesterase PHP domain protein YP_001531453.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein KEGG: sil:SPOA0272 glutathione-dependent formaldehyde dehydrogenase YP_001531454.1 PFAM: GCN5-related N-acetyltransferase KEGG: rle:pRL110290 putative acetyltransferase, no significant swissprot, but middle Ref YP hit to putative acetyltransferase from Rhizobium leguminosarum bv. viciae 3841 YP_001531455.1 PFAM: protein of unknown function DUF88 KEGG: jan:Jann_0048 protein of unknown function DUF88; no swissprot YP_001531456.1 PFAM: regulatory protein TetR KEGG: rsh:Rsph17029_2507 transcriptional regulator, TetR family; TetR family YP_001531457.1 PFAM: Rubrerythrin; protein of unknown function DUF125 transmembrane KEGG: sil:SPO3842 hypothetical protein, may be Rubrerythrin, but Rub has a C-terminal domain homologous to rubredoxin PUBMED:1657933, which is not detected in this case, just the CCC1 like domain at C-terminal, which could be involved in iron and manganese transport YP_001531458.1 KEGG: syw:SYNW1655 hypothetical protein, best ref ZP hit to Methyltransferase type 11 from Methylobacterium sp. 4-46, no IPR scan results YP_001531459.1 PFAM: Auxin Efflux Carrier KEGG: jan:Jann_0051 auxin efflux carrier, best swissprot hit to Putative malonate transporter from Sinorhizobium meliloti (Rhizobium meliloti) and best ref YP hit to Auxin Efflux Carrier from Jannaschia sp. CCS1; COG0679 Predicted permeases YP_001531460.1 PFAM: protein of unknown function DUF188 KEGG: rde:RD1_0321 YaiI/YqxD family protein, putative YP_001531461.1 PFAM: major facilitator superfamily MFS_1 KEGG: rde:RD1_0325 transmembrane transporter, major facilitator family, putative, COG2814 Arabinose efflux permease; major facilitator superfamily (MFS) YP_001531462.1 PFAM: AFG1-family ATPase KEGG: rde:RD1_0326 ATPase, AFG1 family protein YP_001531463.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein KEGG: rsh:Rsph17029_2558 redoxin domain protein; good swissprot hit to Peroxiredoxin-2E-2, chloroplast precursor from Oryza sativa and Ref ZP hit toantioxidant, AhpC/Tsa family, putative from Roseobacter sp. AzwK-3b YP_001531464.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase KEGG: sil:SPO3737 pyridine nucleotide-disulphide oxidoreductase family protein; also good swissprot hits to Rhodocoxin reductase from Rhodococcus erythropolis YP_001531465.1 TIGRFAM: putative methyltransferase PFAM: conserved hypothetical protein KEGG: sil:SPO3738 methyltransferase, putative YP_001531466.1 PFAM: TRAP dicarboxylate transporter- DctP subunit KEGG: pol:Bpro_2121 TRAP dicarboxylate transporter-DctP subunit YP_001531467.1 KEGG: sit:TM1040_2469 methionine aminopeptidase, type I TIGRFAM: methionine aminopeptidase, type I PFAM: peptidase M24; also high swissprot to Methionine aminopeptidase (MAP) (Peptidase M) from Rickettsia prowazekii YP_001531468.1 Regulatory factor involved in maltose metabolism YP_001531469.1 PFAM: molybdopterin binding domain KEGG: rsh:Rsph17029_2583 molybdopterin binding domain COG1058 - Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA YP_001531470.1 PFAM: GCN5-related N-acetyltransferase KEGG: rsq:Rsph17025_2991 GCN5-related N-acetyltransferase YP_001531471.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme PFAM: Carboxymuconolactone decarboxylase KEGG: sit:TM1040_2465 uncharacterised peroxidase-related, no swissprot, but high Ref hits YP_001531472.1 PFAM: OmpA/MotB domain protein KEGG: rsh:Rsph17029_2585 OmpA/MotB domain protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_001531473.1 PFAM: regulatory protein LysR; LysR substrate-binding KEGG: sit:TM1040_2460 transcriptional regulator, LysR family, good RBS site AGGAT; LysR family YP_001531474.1 TIGRFAM: intracellular protease, PfpI family PFAM: ThiJ/PfpI domain protein KEGG: jan:Jann_1867 peptidase C56, PfpI; PfpI family YP_001531475.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase KEGG: sit:TM1040_2458 NADH:flavin oxidoreductase/NADH oxidase, high swissprot to 2,4-dienoyl-CoA reductase [NADPH] from Escherichia coli K12 YP_001531476.1 KEGG: sit:TM1040_2681 hypothetical protein, bad BLAST hits, no IPR Scan results YP_001531477.1 KEGG: sit:TM1040_2680 hypothetical protein; no swissprot, no IPR Scan results YP_001531478.1 KEGG: jan:Jann_0063 hypothetical protein, no significant swissprot, middle Ref hit YP_001531479.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001531480.1 PFAM: Abortive infection protein KEGG: jan:Jann_0061 abortive infection protein, no significant swissprot YP_001531481.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit KEGG: pde:Pden_1987 acetyl-CoA carboxylase, carboxyl transferase, beta subunit, high swissprot; carboxyl transferase, beta subunit YP_001531482.1 TIGRFAM: FolC bifunctional protein PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein KEGG: sil:SPO3818 FolC bifunctional protein YP_001531483.1 KEGG: sil:SPO2586 type I secretion target repeat protein, middle Ref ZP hit, no swissprot, hedgehog domain: in eukaryotes involved in cell growth and differentiation YP_001531484.1 PFAM: transcriptional coactivator/pterin dehydratase KEGG: rde:RD1_0944 pterin-4-alpha-carbinolamine dehydratase YP_001531485.1 PFAM: protein of unknown function DUF482 KEGG: sil:SPO3732 hypothetical protein, no swissprot YP_001531486.1 PFAM: glycerophosphoryl diester phosphodiesterase KEGG: jan:Jann_0436 glycerophosphoryl diester phosphodiesterase PRK: ugpQ YP_001531487.1 PFAM: Endoribonuclease L-PSP COG0251-Putative translation initiation inhibitor, yjgF family YP_001531488.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family PFAM: secretion protein HlyD family protein KEGG: sil:SPO3729 type I secretion membrane fusion protein, HlyD family; also middle swissprot hit to Proteases secretion protein prtE from Erwinia chrysanthemi; HlyD family YP_001531489.1 TIGRFAM: type I secretion system ATPase PFAM: ABC transporter related contains:pfam00005 pfam00664 YP_001531490.1 PFAM: VacJ family lipoprotein KEGG: rsp:RSP_0891 putative lipoprotein, middle swissprot to Lipoprotein vacJ precursor from Shigella flexneri YP_001531491.1 PFAM: toluene tolerance family protein KEGG: rde:RD1_0939 toluene tolerance family protein, putative; swissprot hit to Protein yrbC precursor from Escherichia coli K12 (ABC transporter related) YP_001531492.1 KEGG: rde:RD1_0938 penicillin-binding protein, 1A family TIGRFAM: penicillin-binding protein, 1A family PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; 1A family YP_001531493.1 PFAM: nitrogen regulatory protein P-II KEGG: jan:Jann_4056 nitrogen regulatory protein P-II (GlnB, GlnK), glnK-amtB-Operon (amtB: Dshi_1838); highly conserved gene cluster (e.g. E. coli, R. capsulatus) YP_001531494.1 TIGRFAM: ammonium transporter PFAM: Rh family protein/ammonium transporter KEGG: sit:TM1040_2630 ammonium transporter, high swissprot to Putative ammonium transporter sll0108 from Synechocystis sp. PCC 6803; sequence homolgies; gene arrangement (-> glnK, Dshi_0143) YP_001531495.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001531496.1 PFAM: Rhodanese domain protein KEGG: rsh:Rsph17029_2544 3-mercaptopyruvate sulfurtransferase; both, high swissprot and Ref YP hits to 3-mercaptopyruvate sulfurtransferase (sseA) YP_001531497.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001531498.1 PFAM: GCN5-related N-acetyltransferase KEGG: bur:Bcep18194_B2857 GCN5-related N-acetyltransferase, bad BLAST hits YP_001531499.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001531500.1 PFAM: Lytic transglycosylase catalytic KEGG: rsh:Rsph17029_2541 lytic transglycosylase, catalytic; swissprot to Putative soluble lytic murein transglycosylase precursor from Haemophilus influenzae; IPR Scan: domain to bacterial muramidases superfamily YP_001531501.1 PFAM: protein of unknown function DUF6 transmembrane KEGG: jan:Jann_0141 protein of unknown function DUF6, transmembrane, swissprot hit to S-adenosylmethionine uptake transporter from Rickettsia typhi (DMT related) YP_001531502.1 PFAM: protein of unknown function DUF752 KEGG: sil:SPO3553 hypothetical protein YP_001531503.1 PFAM: FAD dependent oxidoreductase KEGG: sil:SPO3552 oxidoreductase, FAD-binding YP_001531504.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase KEGG: sit:TM1040_2447 NADPH-dependent FMN reductase; predicted flavoprotein COG0431 YP_001531505.1 PFAM: LrgA family protein; bad Ref ZP hit to hypothetical protein RAZWK3B_06232 from Roseobacter sp. AzwK-3b no significant swissprot hit YP_001531506.1 PFAM: LrgB family protein KEGG: pde:Pden_2740 LrgB family protein; gene arrangement wtih Dshi_0155 putative LrgA protein YP_001531507.1 KEGG: ret:RHE_CH02488 cob(I)alamin adenosyltransferase protein TIGRFAM: cob(I)alamin adenosyltransferase PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP, good swissprot hits, good RBS site AGGAT, the following genes are also involved in the vit. B12 biosynthese; alternative gene name: cobO/btuR YP_001531508.1 KEGG: bov:BOV_1269 cobaltochelatase, CobN subunit TIGRFAM: cobaltochelatase, CobN subunit PFAM: CobN/magnesium chelatase; swissprot: high similarity to aerobic cobaltochelatase subunit cobN from Pseudomonas denitrificans; gene arangement from Dshi_0157 to Dshi_0166 Vit B12 synthesis YP_001531509.1 no significant BLAST hits, no IPR Scan result; unsure GC frame plot YP_001531510.1 TIGRFAM: cobalamin biosynthesis protein CobW PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein KEGG: bov:BOV_1270 cobalamin biosynthesis protein CobW, high swissprot hit to Protein cobW from Pseudomonas denitrificans YP_001531511.1 TIGRFAM: cobalt transporter, subunit CbtA PFAM: Cobalt transporter subunit CbtA putative KEGG: sit:TM1040_2222 cobalt transporter subunit CbtA, putative, no swissprot, middle Ref hits YP_001531512.1 KEGG: pde:Pden_2524 hypothetical protein, no swissprot, bad EDO hit to cobalt transporter, subunit CbtB from Methylobacterium populi BJ001, a single transmembrane domain and four times His at C-terminal YP_001531513.1 TIGRFAM: chromosome segregation protein SMC PFAM: SMC domain protein; SMCs flexible hinge domain protein KEGG: rde:RD1_1327 chromosome segregation protein, putative YP_001531514.1 TIGRFAM: lytic murein transglycosylase PFAM: Peptidoglycan-binding domain 1 protein KEGG: sil:SPO3226 hypothetical protein YP_001531515.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001531516.1 PFAM: aminotransferase class I and II KEGG: sil:SPO3224 cobalamin biosynthetic protein CobC; gene arrangement with several genes upstream (Dshi_0157) to downstream (Dshi_0175); L-threonine-O-3-phosphate decarboxylase YP_001531517.1 PFAM: protein of unknown function DUF1636 KEGG: hne:HNE_2170 hypothetical protein; conserved domain COG5469: predicted metal-binding protein; middle Ref ZP hit to hypothetical protein ROS217_22062 from Roseovarius sp. 217 (same COG domain); bad Swissprot hit to Magnesium-chelatase subunit H (Mg-protoporphyrin IX chelatase subunit H) from Rhodobacter sphaeroides 2.4.1: This family contains a domain common to the cobN protein and to magn YP_001531518.1 KEGG: rde:RD1_1333 response regulator, putative; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains YP_001531519.1 KEGG: jan:Jann_0368 putative glutathione S-transferase YP_001531520.1 no significant BLAST hits, bad GC frame plot, no conserved domains detected YP_001531521.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein KEGG: sye:Syncc9902_0843 hypothetical protein; swissprot to Sirohydrochlorin cobaltochelatase (CbiXL) from Bacillus megaterium YP_001531522.1 PFAM: Precorrin-8X methylmutase CbiC/CobH KEGG: bvi:Bcep1808_1609 precorrin-8X methylmutase; alternative gene name: cbiC YP_001531523.1 KEGG: ava:Ava_3558 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001531524.1 TIGRFAM: precorrin-2 C20-methyltransferase PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase KEGG: mag:amb0297 precorrin-2 methylase; alternative gene name: cbiL YP_001531525.1 TIGRFAM: precorrin-3B C17-methyltransferase PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein KEGG: mag:amb0298 precorrin-3B methylase YP_001531526.1 TIGRFAM: precorrin-4 C11-methyltransferase PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase KEGG: mag:amb0514 precorrin-4 methylase, anaerobic equivalent cbiF YP_001531527.1 KEGG: jan:Jann_0367 hypothetical protein, no significant swissprot, no IPR Scan results YP_001531528.1 PFAM: aminotransferase class I and II KEGG: sit:TM1040_2581 aminotransferase, class I and II; middle swissprot to Putative aminotransferase B from Bacillus subtilis (patB) YP_001531529.1 KEGG: rsh:Rsph17029_2532 peptide deformylase TIGRFAM: peptide deformylase PFAM: formylmethionine deformylase YP_001531530.1 TIGRFAM: peptide deformylase PFAM: formylmethionine deformylase KEGG: sit:TM1040_2578 formylmethionine deformylase, worse BLAST hits than Dshi_0179, but same product result YP_001531531.1 TIGRFAM: methionyl-tRNA formyltransferase PFAM: formyl transferase domain protein KEGG: sil:SPO3216 methionyl-tRNA formyltransferase; high swissprot YP_001531532.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001531533.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 KEGG: sil:SPO3211 hypothetical protein YP_001531534.1 KEGG: rde:RD1_1353 hypothetical protein YP_001531535.1 PFAM: phosphatidate cytidylyltransferase KEGG: reu:Reut_B4016 phosphatidate cytidylyltransferase YP_001531536.1 PFAM: phospholipid/glycerol acyltransferase KEGG: reh:H16_A2089 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001531537.1 PFAM: Lysine exporter protein (LYSE/YGGA) KEGG: jan:Jann_0505 lysine exporter protein (LysE/YggA); COG1280 putative threonine efflux protein; Ref hit to Lysine exporter protein (LYSE/YGGA) from Jannaschia sp. CCS1, also swissprot to Homoserine/homoserine lactone efflux protein from Escherichia coli K12 YP_001531538.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001531539.1 PFAM: cytochrome c class I KEGG: rsh:Rsph17029_3996 cytochrome c, class I; COG2863 Cytochrome c553; just middle Ref hits to probable c-type cytochrome from Roseovarius sp. HTCC2601; good RBS site AGGAGGAT YP_001531540.1 KEGG: pmy:Pmen_0684 membrane protein-like protein, middle Ref hits YP_001531541.1 PFAM: protein of unknown function DUF88 KEGG: rsq:Rsph17025_2579 protein of unknown function DUF88 YP_001531542.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK KEGG: sil:SPO3205 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_001531543.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001531544.1 KEGG: rsq:Rsph17025_2576 (p)ppGpp synthetase I, SpoT/RelA TIGRFAM: RelA/SpoT family protein PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein SMART: metal-dependent phosphohydrolase HD region; ppGpp synthetase I; ATP:GTP 3-pyrophosphotransferase YP_001531545.1 KEGG: sil:SPO3202 hypothetical protein YP_001531546.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001531547.1 KEGG: sit:TM1040_1321 hypothetical protein, no swissprot, no conserved domains YP_001531548.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001531549.1 KEGG: rsq:Rsph17025_2572 signal peptidase I TIGRFAM: signal peptidase I PFAM: peptidase S24 and S26 domain protein YP_001531550.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein KEGG: rde:RD1_1366 ribonuclease III YP_001531551.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001531552.1 PFAM: protein of unknown function DUF1491 KEGG: sil:SPO0690 hypothetical protein YP_001531553.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001531554.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain KEGG: rde:RD1_1372 isobutyryl-CoA dehydrogenase YP_001531555.1 PFAM: protein of unknown function DUF81 KEGG: sit:TM1040_2445 protein of unknown function DUF81; no significant swissprot YP_001531556.1 KEGG: rde:RD1_1384 hypothetical protein, no significant swissprot, but conserved domains and good RBS site AGGAT YP_001531557.1 TIGRFAM: phosphocarrier, HPr family PFAM: phosphocarrier HPr protein KEGG: sit:TM1040_2436 phosphotransferase system, HPr; phosphocarrier protein HPr YP_001531558.1 PFAM: PTS system fructose subfamily IIA component KEGG: sil:SPO0714 PTS system IIA component, Man family; Man family protein YP_001531559.1 PFAM: conserved hypothetical protein KEGG: rsh:Rsph17029_0317 uncharacterised P-loop ATPase protein UPF0042; high swissprot, part of the PTS system in gene neighborhood? YP_001531560.1 KEGG: sil:SPO0712 HPr serine kinase/phosphatase domain protein YP_001531561.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein KEGG: rsh:Rsph17029_0315 histidine kinase YP_001531562.1 PFAM: response regulator receiver; transcriptional regulator domain protein KEGG: sit:TM1040_2441 two component transcriptional regulator, winged helix family; winged helix family YP_001531563.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001531564.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001531565.1 KEGG: rde:RD1_1386 hypothetical protein; no significant swissprot; no IPR Scan results YP_001531566.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit KEGG: rde:RD1_1387 electron transfer flavoprotein, alpha subunit, high swissprot YP_001531567.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit KEGG: sil:SPO0720 electron transfer flavoprotein, beta subunit; high swissprot to Electron transfer flavoprotein subunit beta from Paracoccus denitrificans YP_001531568.1 TIGRFAM: ATP--cobalamin adenosyltransferase PFAM: cobalamin adenosyltransferase KEGG: rde:RD1_1389 cob(I)alamin adenosyltransferase, putative YP_001531569.1 KEGG: rsq:Rsph17025_2554 hypothetical protein; no significant swissprot; no conserved domains YP_001531570.1 PFAM: short-chain dehydrogenase/reductase SDR KEGG: rde:RD1_1391 oxidoreductase, putative YP_001531571.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001531572.1 KEGG: rsh:Rsph17029_0330 hypothetical protein, no significant swissprot YP_001531573.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001531574.1 bad Ref ZP hit to methyltransferase FkbM from Lyngbya sp. PCC 8106, no significant swissprot hit, conserved domain related to S-adenosyl-L-methionine-dependent methyltransferases YP_001531575.1 KEGG: pde:Pden_3026 hypothetical protein, no swissprot, bad Ref hits, no conserved domains detected YP_001531576.1 PFAM: protein of unknown function DUF1244 KEGG: sil:SPO3602 hypothetical protein; no significant swissprot hit YP_001531577.1 PFAM: N-formylglutamate amidohydrolase KEGG: jan:Jann_0446 N-formylglutamate amidohydrolase; high Ref hit, but no significant swissprot hit YP_001531578.1 KEGG: rsp:RSP_1766 pyruvate kinase TIGRFAM: pyruvate kinase PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; high swissprot YP_001531579.1 bad BLAST hits, best swissprot to Prolyl-tRNA synthetase from Haemophilus ducreyi, but very unsure; no conserved domains detected YP_001531580.1 PFAM: ribosomal protein L35 KEGG: sil:SPO3599 ribosomal protein L35; high swissprot YP_001531581.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001531582.1 KEGG: sil:SPO2161 hypothetical protein; no significant swissprot, best Ref ZP hit to type I secretion target repeat protein from Roseovarius sp. 217; Hedgehog hintN domain detected YP_001531583.1 PFAM: Citrate transporter KEGG: mgm:Mmc1_1728 citrate transporter; best Ref ZP hit to sulfur deprivation response regulator from Rhodobacterales bacterium HTCC2150, best swissprot toUncharacterized transporter sll0640 from Synechocystis sp. PCC 6803; CitMHS domain detected (citrate transporter) YP_001531584.1 KEGG: sil:SPO2161 hypothetical protein; no significant swissprot hit, Hedgehog/intein (Hint) domain, Ref ZP hit to type I secretion target repeat protein fromRoseovarius sp. 217; same like Dshi_232 YP_001531585.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001531586.1 no swissprot, bad Ref ZP hit to phenylalanyl-tRNA synthetase beta subunit from Loktanella vestfoldensis SKA53, no conserved domains, just short signalpeptide and two transmembrane regions, bad GC frame plot, maybe Dshi_0236 is part of Dshi_0237? YP_001531587.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001531588.1 KEGG: sil:SPO3492 hypothetical protein; no swissprot; best Ref hit to succinate dehydrogenase iron-sulfur subunit from Roseobacter sp. AzwK-3b; no conserved domains YP_001531589.1 PFAM: aspartate dehydrogenase; homoserine dehydrogenase NAD-binding KEGG: mes:Meso_0824 aspartate dehydrogenase YP_001531590.1 PFAM: Glutathione S-transferase domain KEGG: sil:SPO3494 glutathione S-transferase family protein YP_001531591.1 TIGRFAM: large conductance mechanosensitive channel protein PFAM: large-conductance mechanosensitive channel KEGG: jan:Jann_0457 large conductance mechanosensitive channel protein YP_001531592.1 PFAM: fatty acid hydroxylase KEGG: hne:HNE_0606 hypothetical protein; no significant swissprot hit, middle Ref YP hit to hypothetical protein HNE_0606 from Hyphomonas neptunium ATCC 15444, Erg3 domain: sterol desaturase and fatty acid hydroxylase superfamily domain YP_001531593.1 PFAM: acyltransferase 3 KEGG: hne:HNE_0605 acyltransferase family protein; bad swissprot to transferases, middle Ref YP hit to acyltransferase family protein from Hyphomonas neptunium ATCC 15444 YP_001531594.1 TIGRFAM: alanine dehydrogenase PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; alanine dehydrogenase/PNT domain protein KEGG: sit:TM1040_3628 alanine dehydrogenase; high swissprot YP_001531595.1 PFAM: regulatory protein AsnC/Lrp family KEGG: jan:Jann_0459 transcriptional regulator, AsnC family; AsnC family YP_001531596.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001531597.1 TIGRFAM: rpsU-divergently transcribed protein PFAM: COQ9 domain protein KEGG: rde:RD1_1038 hypothetical protein, best Ref hits to hypothetical proteins, middel swissprot hit to Ubiquinone biosynthesis protein COQ9 from Drosophila melanogaster (fruit fly), gene arrangement with following gene (Dshi_0248 quinone oxidoreductase)? YP_001531598.1 TIGRFAM: Quinone oxidoreductase putative PIG3 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein KEGG: rsq:Rsph17025_2435 alcohol dehydrogenase, zinc-binding domain protein YP_001531599.1 located downstream of an ORF representing the N-terminal part of RND subunit, putative sequencing error colocated with MFP subunit; pfam00873,; RND family, C-terminal part of RND subunit YP_001531600.1 located upstream of an ORF representing the C-terminal part of RND subunit, putative sequencing error colocated with MFP subunit; pfam00873,; RND family, N-terminal part of RND subunit YP_001531601.1 colocated with RND subunit; TIGRFAM: efflux transporter, RND family, MFP subunit PFAM: secretion protein HlyD family protein KEGG: jan:Jann_1310 secretion protein HlyD; RND family, MFP subunit YP_001531602.1 PFAM: regulatory protein TetR KEGG: jan:Jann_1309 transcriptional regulator, TetR family; TetR family YP_001531603.1 PFAM: AMP-dependent synthetase and ligase KEGG: sil:SPO0801 4-coumarate:CoA ligase; high swissprot to 4-coumarate--CoA ligase 1 from Nicotiana tabacum YP_001531604.1 PFAM: ribonuclease T2 KEGG: jan:Jann_3879 ribonuclease T2, unsure GC frame plot YP_001531605.1 PFAM: protein of unknown function DUF1013 KEGG: rde:RD1_1043 hypothetical protein YP_001531606.1 no significant BLAST hits, no conserved domains YP_001531607.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin KEGG: sma:SAV5709 protease; good swissprot to Subtilisin E precursor from Bacillus subtilis YP_001531608.1 part of the sec system translocase YP_001531609.1 TIGRFAM: transcription termination/antitermination factor NusG PFAM: KOW domain protein; NGN domain protein KEGG: rsq:Rsph17025_2547 NusG antitermination factor YP_001531610.1 binds directly to 23S ribosomal RNA YP_001531611.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001531612.1 KEGG: jan:Jann_2686 hypothetical protein; PEP-CTERM putative exosortase interaction domain; no significant swissprot, bad Ref hits YP_001531613.1 TIGRFAM: methyltransferase FkbM family KEGG: jan:Jann_0310 methyltransferase FkbM; no significant swissprot YP_001531614.1 KEGG: jan:Jann_2490 hemolysin-type calcium-binding protein, middle Ref hits to hypothetical proteins, no swissprot, C-terminal beginning of unsure GC frame plot YP_001531615.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001531616.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001531617.1 KEGG: pde:Pden_2598 PpiC-type peptidyl-prolyl cis-trans isomerase; bad BLAST hits, unsure GC frame plot, RBS site AGGAT YP_001531618.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001531619.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001531620.1 PFAM: protein of unknown function DUF6 transmembrane KEGG: sil:SPO3504 hypothetical protein; best Ref ZP hit to membrane protein, putative and bad swissprot to S-adenosylmethionine uptake transporter from Rickettsia typhi YP_001531621.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001531622.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001531623.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001531624.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001531625.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001531626.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001531627.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001531628.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001531629.1 no significant BLAST hits, no conserved domains, unsure GC frame plot YP_001531630.1 KEGG: rde:RD1_1404 hypothetical protein, no significant swissprot hit, unsure GC frame plot YP_001531631.1 KEGG: rde:RD1_3741 YHS domain protein, no swissprot; is located in the midst of a unsure GC frame plot region YP_001531632.1 no swissprot, bad Ref hits, no conserved domains, unsure GC frame plot YP_001531633.1 no swissprot, bad Ref hits, no conserved domains, unsure GC frame plot YP_001531634.1 KEGG: rsq:Rsph17025_2139 hypothetical protein; bad swissprot to 31 kDa outer-membrane immunogenic protein precursor from Brucella melitensis; middle Ref ZP hit to possible outer membrane protein from Roseovarius sp. 217; Autotransporter beta-domain YP_001531635.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001531636.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001531637.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001531638.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001531639.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001531640.1 KEGG: sit:TM1040_3827 hypothetical protein; short signalpeptide and three transmembrane region; no swissprot, bad Ref hits to hypothetical proteins YP_001531641.1 KEGG: rde:RD1_0735 hypothetical protein; bad Ref hits to hypothetical proteins; short signalpeptide and four transmembrane regions; no significant swissprot YP_001531642.1 KEGG: sil:SPO0491 hypothetical protein; no swissprot; TIGR02466 conserved hypothetical protein YP_001531643.1 one of the stabilizing components for the large ribosomal subunit YP_001531644.1 PFAM: ribosomal protein S17 KEGG: sit:TM1040_0263 ribosomal protein S17 YP_001531645.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001531646.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001531647.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001531648.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001531649.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001531650.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001531651.1 binds 5S rRNA along with protein L5 and L25 YP_001531652.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001531653.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001531654.1 late assembly protein YP_001531655.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001531656.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001531657.1 PFAM: ribosomal protein S13 KEGG: sil:SPO0509 ribosomal protein S13 YP_001531658.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001531659.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001531660.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001531661.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein KEGG: pde:Pden_0786 response regulator receiver protein, Autoinducer binding domain pfam03472, HTH-LuxR domain pfam00196; LuxR family YP_001531662.1 KEGG: pde:Pden_0787 N-acyl-L-homoserine lactone synthetase-like YP_001531663.1 PFAM: magnesium chelatase ChlI subunit; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5 SMART: AAA ATPase KEGG: sil:SPO0515 ATPase, AAA family YP_001531664.1 PFAM: Camphor resistance CrcB protein KEGG: rde:RD1_1440 CrcB-like protein; COG0239 Integral membrane protein possibly involved in chromosome condensation YP_001531665.1 high Ref YP hit to Pseudouridine synthase, RluD from Jannaschia sp. CCS1 and middle swissprot hit to Ribosomal large subunit pseudouridine synthase C from Pasteurella multocida; RNA binding and rluC domain (PF00849) YP_001531666.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1 PFAM: Haloacid dehalogenase domain protein hydrolase KEGG: rde:RD1_1442 hydrolase, putative; PGPase YP_001531667.1 PFAM: ATP12 ATPase KEGG: rsp:RSP_1746 hypothetical protein; good Ref hits to ATP12 proteins, also middle swissprot hit toATP synthase mitochondrial F1 complex assembly factor 2, mitochondrial precursor (ATP12 homolog) from Homo sapiens YP_001531668.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein SMART: extracellular solute-binding protein family 3 KEGG: sil:SPO0519 glutamate/glutamine/aspartate/asparagine ABC transporter, periplasmic substrate-binding protein; high swissprot hit to Glutamate/glutamine/aspartate/asparagine-binding protein bztA from Rhodobacter capsulatus; RBS site AGGAT YP_001531669.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit PFAM: binding-protein-dependent transport systems inner membrane component KEGG: rde:RD1_1445 glutamate/glutamine/aspartate/asparagine transport system permease protein, high swissprot YP_001531670.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit PFAM: binding-protein-dependent transport systems inner membrane component KEGG: rde:RD1_1446 amino acid ABC transporter, permease protein, high swissprot to Glutamate/glutamine/aspartate/asparagine transport system permease from Rhodobacter capsulatus YP_001531671.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: jan:Jann_0630 ABC transporter related, high swissprot hit to Glutamate/glutamine/aspartate/asparagine transport ATP-binding from Rhodobacter capsulatus YP_001531672.1 PFAM: Phosphoglycerate mutase KEGG: sil:SPO0523 phosphoglycerate mutase family protein; COG2062 Phosphohistidine phosphatase SixA; best Ref hits to hypothetical proteins YP_001531673.1 KEGG: rde:RD1_1449 hypothetical protein, no significant swissprot; no conserved domains detected YP_001531674.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001531675.1 PFAM: short-chain dehydrogenase/reductase SDR , good swissprot hit to Protein fixR from Bradyrhizobium japonicum, fabG NCBI domain, good Ref ZP hit toShort-chain alcohol dehydrogenase from Rhodobacterales bacterium HTCC2150 YP_001531676.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001531677.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein KEGG: sil:SPO0531 MOSC domain protein, swissprot hit to Molybdenum cofactor sulfurase from Mus musculus YP_001531678.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001531679.1 TIGRFAM: diguanylate cyclase PFAM: GGDEF domain containing protein; EAL domain protein KEGG: sil:SPO0533 diguanylate cyclase, putative YP_001531680.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001531681.1 PFAM: protein of unknown function DUF37; middle swissprot hit to UPF0161 protein RD1_1458 from Roseobacter denitrificans OCh 114 and middle Ref ZP hit to hypothetical protein SKA53_00415 from Loktanella vestfoldensis SKA53 YP_001531682.1 TIGRFAM: ribonuclease P protein component PFAM: ribonuclease P protein , middle swissprot hit to Ribonuclease P protein component from Silicibacter pomeroyi and middle Ref ZP hit toribonuclease P protein component from Roseobacter sp. CCS2 YP_001531683.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001531684.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; low swissprot hit to Sensor protein zraS (a membrane-associated protein kinase that phosphorylates zraR in response to high concentrations of zinc or lead in the medium) from Salmonella typhimurium and high Ref ZP hit to periplasmic sensor signal transduction histidine kinase from R YP_001531685.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; high swissprot to Mercuric reductase from Bacillus cereus and high Ref ZP hit to mercuric reductase, putative from Roseovarius sp. TM1035 YP_001531686.1 PFAM: SNARE associated Golgi protein KEGG: rde:RD1_1463 mercuric reductase; the mercuric reductase MerA also comprises a SNARE associated Golgi protein motif, low swissprot hit to UPF0043 membrane protein ydjX from Escherichia coli K12 and good Ref ZP hit to hypothetical protein RCCS2_07124 from Roseobacter sp. CCS2; also good Ref YP hit to mercuric reductase from Roseobacter denitrificans OCh 114; possible Gene arrangement with Dshi_0335 YP_001531687.1 PFAM: ATPase MipZ KEGG: jan:Jann_0738 ATPases involved in chromosome partitioning-like;alternative gene name: mipZ YP_001531688.1 PFAM: beta-lactamase domain protein KEGG: sil:SPO2170 metallo-beta-lactamase family protein; NCBI conserved domains:GloB, Zn-dependent hydrolases, including glyoxylases; no significant swissprot YP_001531689.1 PFAM: protein of unknown function DUF849 KEGG: bur:Bcep18194_B0612 protein of unknown function DUF849, no significant swissprot YP_001531690.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001531691.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001531692.1 KEGG: rsq:Rsph17025_0184 tRNA (guanine-N1)-methyltransferase TIGRFAM: tRNA (guanine-N1)-methyltransferase PFAM: tRNA (guanine-N1-)-methyltransferase YP_001531693.1 PFAM: aminoglycoside phosphotransferase KEGG: sit:TM1040_2610 hypothetical protein; no significant swissprot hit YP_001531694.1 Essential for efficient processing of 16S rRNA YP_001531695.1 no significant BLAST hits, unsure prosite hit to ribosomal protein S2 YP_001531696.1 PFAM: protein of unknown function DUF55 KEGG: mjl:Mjls_0045 protein of unknown function DUF55, bad swissprot hit to UPF0310 protein in gntR 5region fromBacillus licheniformis; bad Ref ZP hit to UPF0310 protein in gntR 5region fromBacillus licheniformis YP_001531697.1 KEGG: sil:SPO3254 cobalamin biosynthesis protein BluB TIGRFAM: cob(II)yrinic acid a,c-diamide reductase PFAM: nitroreductase; good swissprot hit toPutative cob(II)yrinic acid a,c-diamide reductase from Rhodobacter capsulatus YP_001531698.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001531699.1 catalyzes the interconversion of chorismate to prephenate YP_001531700.1 KEGG: sit:TM1040_2605 hypothetical protein, no significant swissprot, good Ref YP hit to acetyltransferase, GNAT family from Roseobacter denitrificans OCh 114, NCBI conserved domains: rimL YP_001531701.1 PFAM: GCN5-related N-acetyltransferase KEGG: jan:Jann_0752 GCN5-related N-acetyltransferase; middle Ref YP hit to GCN5-related N-acetyltransferase from Jannaschia sp. CCS1; NCBI conserved domains: rimL YP_001531702.1 middle Ref ZP hit to acetyltransferase, GNAT family protein from Roseobacter sp. CCS2, no significant swissprot, NCBI domains: rimL; prosite51186 GCN5-related N-acetyltransferase ; GNAT family YP_001531703.1 KEGG: rde:RD1_1315 signal recognition particle protein, putative TIGRFAM: signal recognition particle protein PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle SMART: AAA ATPase; high swissprot to Signal recognition particle protein from Rickettsia typhi YP_001531704.1 Pfam02525 Flavodoxin-like fold, NCBI conserved domains PRK00170 azoreductase, middle Ref ZP hit to (Acyl-carrier protein) phosphodiesterase from Roseobacter sp. SK209-2-6, middle swissprot hit toFMN-dependent NADH-azoreductase 1 from Jannaschia sp. CCS1; at N-terminal unsure GC frame plot YP_001531705.1 PFAM: regulatory protein LysR; LysR substrate-binding KEGG: sit:TM1040_2599 transcriptional regulator, LysR family; high Ref Yp hit to transcriptional regulator, LysR family from Silicibacter sp. TM1040; LysR family YP_001531706.1 PFAM: protein of unknown function DUF6 transmembrane KEGG: rde:RD1_1318 integral membrane protein, putative; no significant swissprot; high Ref Yp hit to integral membrane protein, putative from Roseobacter denitrificans OCh 114, no conserved domains by NCBI; ten transmembrane regions YP_001531707.1 PFAM: regulatory protein ArsR KEGG: sit:TM1040_2597 transcriptional regulator, ArsR family; middle Ref ZP hit to transcriptional regulator, ArsR family protein from Roseovarius sp. TM1035; bad swissprot hit to cadC: Cadmium efflux system accessory protein from Listeria monocytogenes; ArsR family YP_001531708.1 involved in de novo purine biosynthesis YP_001531709.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001531710.1 KEGG: rsq:Rsph17025_2930 hypothetical protein; no significant swissprot, no conserved domains YP_001531711.1 PFAM: peptidase M16 domain protein; high swissprot to Uncharacterized zinc protease y4wA fromRhizobium sp. NGR234 and high Ref ZP hit to putative zinc protease from Rhodobacterales bacterium HTCC2150; NCBI conserved domains: pqqL YP_001531712.1 PFAM: peptidase M16 domain protein; good swissprot to Uncharacterized zinc protease-like protein y4wB from Rhizobium sp. NGR234 and Ref YP hit to peptidase M16 domain protein from Rhodobacter sphaeroides ATCC 17025, NCBI conserved domains: pqqL YP_001531713.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001531714.1 PFAM: protein of unknown function DUF195 ; NCBI conserved domains: rmuC; swissprot to DNA recombination protein rmuC homolog from Xylella fastidiosa Temecula1 and high Ref ZP hit to RmuC domain protein from Oceanicola batsensis HTCC2597 YP_001531715.1 TIGRFAM: anti-sigma factor, putative, ChrR family PFAM: Cupin 2 conserved barrel domain protein; good swissprot to Transcriptional activator chrR from Rhodobacter sphaeroides 2.4.1 and good Ref ZP hit to Anti-sigma factor ChrR from Roseovarius sp. TM1035; NCBI conserved domains: chrR; ChrR YP_001531716.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001531717.1 PFAM: amine oxidase; FAD dependent oxidoreductase, no significant swissprot, high ref ZP hit to Putative cyclopropane/cyclopropene fatty acid synthesis protein, flavin amine oxidase from Sulfitobacter sp. NAS-14.1 YP_001531718.1 PFAM: protein of unknown function DUF1365; no significant swissprot, high Ref YP hit to protein of unknown function DUF1365 from Jannaschia sp. CCS1 YP_001531719.1 bad swissprot hit to Uncharacterized symporter ynaJ from Bacillus subtilis and high Ref ZP hit to sodium:galactoside symporter family protein, putative from Roseobacter sp. CCS2; PF07690 MFS_1: transporter, major facilitator family YP_001531720.1 no significant swissprot, good Ref ZP hit to hypothetical protein RCCS2_10850 from Roseobacter sp. CCS2; no NCBI conserved domains YP_001531721.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; middle swissprot hit to Uncharacterized oxidoreductase MXAN_5909 from Myxococcus xanthus DK 1622, good Ref ZP hit to Short-chain dehydrogenase/reductase family member from Loktanella vestfoldensis SKA53; NCBI conserved domains: COG4221, Short-chain alcohol dehydrogenase of unknown specificity YP_001531722.1 no conserved domains detected, no significant swissprot, middle Ref ZP hit to hypothetical protein SKA53_12618 from Loktanella vestfoldensis SKA53 YP_001531723.1 PFAM: AMP-dependent synthetase and ligase, good swissprot hit to Putative long-chain-fatty-acid--CoA ligase from Haemophilus influenzae and high Ref ZP hit to AMP-binding enzyme from Rhodobacterales bacterium HTCC2654; NCBI conserved domains: COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_001531724.1 no significant BLAST hits, no conserved domains detected; normal GC frame plot YP_001531725.1 PFAM: ABC transporter related SMART: AAA ATPase, good swissprot to High-affinity branched-chain amino acid transport ATP-binding protein from Pseudomonas aeruginosa and high Ref ZP hit tobranched-chain amino acid ABC transporter, ATP-binding protein from Rhodobacterales bacterium HTCC2654; NCBI conserved domains: livG; gene arrangement (ABC transporter) with following genes to Dshi_0381 YP_001531726.1 PFAM: inner-membrane translocator KEGG: rde:RD1_0704 branched-chain amino acid ABC transporter, permease protein, putative, low swissprot hit to High-affinity branched-chain amino acid transport system permease protein livH from Escherichia coli K12 and high Ref ZP hit to ABC branched amino acid transporter family, inner membrane subunit from Rhodobacterales bacterium HTCC2654, NCBI conserved doma YP_001531727.1 no significant BLAST hits, unsure GC frame plot, no conserved domains detected, lies in the middle of ABC transporter YP_001531728.1 no significant BLAST hits, unsure GC frame plot, no conserved domains detected, lies in the middle of ABC transporter YP_001531729.1 PFAM: inner-membrane translocator KEGG: sil:SPO3292 branched-chain amino acid ABC transporter, permease protein; middle swissprot hit to High-affinity branched-chain amino acid transport system permease protein livM from Salmonella typhimurium and high Ref YP hit to inner-membrane translocator from Jannaschia sp. CCS1; NCBI conserved domains:livM; gene arrangement with Dshi_0375 to Dshi_0381 YP_001531730.1 pfam01094 Receptor family ligand binding region; bad swissprot hit to Leu/Ile/Val-binding protein homolog 3 precursor from Brucella suis and high Ref ZP hit to branched-chain amino acid ABC transporter, periplasmic from Roseobacter sp. MED193; gene arrangement with Dshi_0375 to Dshi_0381 YP_001531731.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: jan:Jann_4003 ABC transporter related, good swissprot hit to High-affinity branched-chain amino acid transport ATP-binding protein livF from Salmonella typhimurium and high Ref ZP hit to ABC transporter related protein from Roseobacter sp. CCS2, NCBI conserved domains: livF; gene cluster from Dshi_0375 to Dshi_0381 YP_001531732.1 SSF56801 Acetyl-CoA sythase-like, low swissprot hit to Phenylacetate-coenzyme A ligase from Escherichia coli K12 and high Ref Yp hit to phenylacetate-CoA ligase, putative from Silicibacter sp. TM1040; NCBI conserved domains:paaK YP_001531733.1 no significant BLAST hits, unsure GC frame plot, no conserved domains YP_001531734.1 KEGG: bur:Bcep18194_B1502 NUDIX hydrolase; no significant swissprot, bad Ref YP hit to NUDIX hydrolase from Burkholderia sp. 383; no conserved domains by Interpro Scan, NCBI conserved domains:NUDIX hydrolase 23 YP_001531735.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001531736.1 PFAM: N-formylglutamate amidohydrolase KEGG: rde:RD1_0718 N-formylglutamate amidohydrolase, putative; no signifcant swissprot; good Ref ZP hit to N-formylglutamate amidohydrolase family protein from Loktanella vestfoldensis SKA53; NCBI conserved domains: hutG YP_001531737.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001531738.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: sit:TM1040_0370 ABC transporter related; good swissprot hit to Ribose import ATP-binding protein rbsA from Anabaena variabilis and high Ref ZP hit to sugar ABC transporter, ATP-binding protein, putative from Roseobacter sp. CCS2 YP_001531739.1 PFAM: inner-membrane translocator KEGG: sit:TM1040_0369 inner-membrane translocator; middle swissprot hit to Ribose transport system permease protein rbsC from Bacillus subtilis and high Ref YP hit to inner-membrane translocator from Silicibacter sp. TM1040 YP_001531740.1 PFAM: periplasmic binding protein/LacI transcriptional regulator KEGG: sit:TM1040_0368 periplasmic binding protein/LacI transcriptional regulator; low swissprot hit to D-ribose-binding periplasmic protein precursor from Salmonella typhimurium and high Ref YP hit to periplasmic binding protein/LacI transcriptional regulator from Silicibacter sp. TM1040; NCBI conserved domains:rbsB YP_001531741.1 no significant swissprot, high Ref ZP hit to hypothetical protein MELB17_00320 from Marinobacter sp. ELB17; pfam02810 SEC-C motif YP_001531742.1 no significant swissprot, high Ref hit to hypothetical protein TM1040_3581 from Silicibacter sp. TM1040; no conserved domains, unsure GC frame plot YP_001531743.1 no significant swissprot, no conserved domains, bad Ref Yp hit to hypothetical protein TM1040_3583 from Silicibacter sp. TM1040, bad GC frame plot, CRISPR region YP_001531744.1 no significant swissprot, no conserved domains, bad GC frame plot; bad Ref Yp hit to hypothetical protein TM1040_3584 from Silicibacter sp. TM1040; CRISPR region YP_001531745.1 PFAM: integrase family protein KEGG: sit:TM1040_3585 phage integrase; COG4974 - Site-specific recombinase XerD; high Ref YP hit to phage integrase from Silicibacter sp. TM1040 and bad swissprot hit to Putative prophage CPZ-55 integrase from Escherichia coli K12; bad GC frame plot, CRISPR region YP_001531746.1 PFAM: Resolvase domain; Recombinase KEGG: pde:Pden_3123 recombinase; COG1961 - Site-specific recombinases, DNA invertase Pin homologs; bad swissprot hit toPutative DNA recombinase from Bacillus subtilis and high Ref ZP hit toResolvase, N-terminal:Recombinase from Paracoccus denitrificans PD1222; bad GC frame plot, CRISPR region YP_001531747.1 PFAM: integrase family protein ; low swissprot hit to Tyrosine recombinase xerD from Bacillus subtilis and middle Ref EDP hit to phage integrase from alpha proteobacterium BAL199; NCBI conserved domains: xerDC; CRISPR region YP_001531748.1 PFAM: integrase family protein; COG4974 - Site-specific recombinase XerD; bad swissprot hit to Tyrosine recombinase xerC from Pseudomonas aeruginosa and good Ref ZP hit to phage integrase from Roseovarius sp. HTCC2601; CRISPR region YP_001531749.1 TIGRFAM: DNA binding domain, excisionase family PFAM: regulatory protein MerR; NCBI conserved domains: HTH_MerR-trunc; bad Ref YP hit to DNA binding domain, excisionase family from Alkaliphilus oremlandii OhILAs and bad swissprot hit to Gene 36 protein from Mycobacterium phage D29; bad GC frame plot; Dshi_0400 to Dshi_0402 CRISPRs; excisionase family YP_001531750.1 TIGRFAM: CRISPR-associated protein, Csn1 family ; no significant swissprot, high Ref YP hit to CRISPR-associated protein, Csn1 family from Verminephrobacter eiseniae EF01-2; Csn1 family YP_001531751.1 TIGRFAM: CRISPR-associated protein Cas1 KEGG: vei:Veis_1231 CRISPR-associated protein Cas1, no significant swissprot, good Ref YP hit to CRISPR-associated protein Cas1 from Verminephrobacter eiseniae EF01-2 YP_001531752.1 TIGRFAM: CRISPR-associated protein Cas2 KEGG: vei:Veis_1232 CRISPR-associated protein Cas2; no significant swissprot; low Ref YP hit to CRISPR-associated protein Cas2 from Verminephrobacter eiseniae EF01-2 YP_001531753.1 PFAM: transposase IS3/IS911 family protein; NCBI conserved domains: transposase_8; middle Ref ZP hit to Insertion element ISR1 hypothetical 10 kDa protein A3 from Sagittula stellata E-37; middle swissprot to Insertion element ISR1 uncharacterized 10 kDa protein A3 from Rhizobium sp. YP_001531754.1 PFAM: Integrase catalytic region KEGG: bbt:BBta_7691 integrase, catalytic domain; good swissprot hit toInsertion element IS476 uncharacterized 39.2 kDa protein from Xanthomonas euvesicatoria; high Ref Yp hit to Integrase catalytic region from Xanthobacter autotrophicus Py2; downstream of CRISPR region YP_001531755.1 no significant BLAST hits, no conserved domains, unsure GC frame plot, downstream of CRISPR region YP_001531756.1 no significant BLAST hits, no conserved domains, unsure GC frame plot YP_001531757.1 PFAM: helix-turn-helix domain protein KEGG: nmu:Nmul_D2824 transcriptional regulator, XRE family; no significant swissprot, middle Ref YP hit to transcriptional regulator, XRE family from Nitrosospira multiformis ATCC 25196; XRE family YP_001531758.1 PFAM: protein of unknown function DUF955 KEGG: nmu:Nmul_D2822 hypothetical protein; no significant swissprot; middle Ref YP hit to hypothetical protein Nmul_D2822 from Nitrosospira multiformis ATCC 25196 YP_001531759.1 KEGG: nwi:Nwi_1958 hypothetical protein; no significant swissprot, middle Ref YP hit to hypothetical protein Nwi_1958 from Nitrobacter winogradskyi Nb-255, no conserved domains detected YP_001531760.1 good Ref Yp hit to hypothetical protein RD1_0494 from Roseobacter denitrificans OCh 114; no significant swissprot; short signalpeptide and two transmembrane regions; unsure GC frame plot YP_001531761.1 good Ref YP hit to hypothetical protein RD1_0495 from Roseobacter denitrificans OCh 114; no significant swissprot; no NCBI conserved domains; PS00092 N-6 Adenine-specific DNA methylase YP_001531762.1 PFAM: beta-Ig-H3/fasciclin; Hemolysin-type calcium-binding region KEGG: pde:Pden_0560 hemolysin-type calcium-binding region; NCBI conserved domains: Fasciclin; middle Ref YP hit to Beta-Ig-H3/fasciclin from Ralstonia eutropha JMP134; no significant swissprot YP_001531763.1 no significant swissprot, unsure GC frame Plot, no conserved domains detected by InterPro Scan; NCBI conserved domains: COG1373 - Predicted ATPase (AAA+ superfamily); middle Ref ZP hit tohypothetical protein RTM1035_00450 from Roseovarius sp. TM1035 YP_001531764.1 KEGG: pde:Pden_4724 GreA/GreB family elongation factor; bad swissprot hit to Transcription elongation factor greA from Brucella suis; middle Ref ZP hit to putative nucleoside diphosphate kinase regulator from Oceanicola batsensis HTCC2597; NCBI conserved domains: PRK05753, nucleoside diphosphate kinase regulator and GreA/B YP_001531765.1 no significant BLAST hits, no conserved domains; unsure GC frame plot YP_001531766.1 PFAM: protein of unknown function DUF1127; bad Ref ZP hit to hypothetical protein OB2597_05265 from Oceanicola batsensis HTCC2597; no significant swissprot, unsure GC frame plot YP_001531767.1 no significant BLAST hits, no conserved domains, unsure GC frame plot YP_001531768.1 PFAM: UspA domain protein KEGG: hha:Hhal_1414 UspA domain protein; COG0589 - Universal stress protein UspA and related nucleotide-binding proteins, bad swissprot hit to Stress response protein nhaX from Bacillus subtilis; low Ref YP hit to UspA domain protein from Halorhodospira halophila SL1, NCBI conserved domains:Usp/UspA like YP_001531769.1 PFAM: major facilitator superfamily MFS_1 KEGG: sal:Sala_2954 major facilitator superfamily MFS_1; middle swissprot hit to Uncharacterized MFS-type transporter ycaD from Salmonella typhi and good Ref ZP hit to major facilitator family transporter from Sphingomonas sp. SKA58 YP_001531770.1 PFAM: Endonuclease/exonuclease/phosphatase KEGG: sil:SPO2482 endonuclease/exonuclease/phosphatase family protein; no significant swissprot; good Ref EDP hit to metal-dependent hydrolase from Oceanibulbus indolifex HEL-45, NCBI conserved domains: elsH, Metal-dependent hydrolase YP_001531771.1 PFAM: phospholipase D/Transphosphatidylase KEGG: pmy:Pmen_2055 phospholipase D/transphosphatidylase; high swissprot hit to Uncharacterized protein ymdC from Escherichia coli K12 and high Ref EDP hit to phospholipase D/Transphosphatidylase from Oceanibulbus indolifex HEL-45; NCBI conserved domains: PLDc YP_001531772.1 PFAM: Propeptide PepSY amd peptidase M4 KEGG: swi:Swit_4515 hypothetical protein; no significant swissprot; bad gb hit to Propeptide, PepSY amd peptidase M4 from Oceanibulbus indolifex HEL-45 YP_001531773.1 PFAM: phosphoesterase PA-phosphatase related KEGG: rsh:Rsph17029_1755 phosphoesterase, PA-phosphatase related, no significant swissprot; good Ref YP hit to PA-phosphatase related phosphoesterase from Rhodobacter sphaeroides 2.4.1; NCBI conserved domains: Pap2-like YP_001531775.1 no significant swissprot; PD068243 REGULATORY BACTERIAL FAMILY MERR CYTOPLASMIC; middle Ref ZP hit to hypothetical protein ROS217_15345 from Roseovarius sp. 217 YP_001531776.1 no significant swissprot, no conserved domains (except for one signalpeptide/ two transmembr. region), bad Ref YP hit to hypothetical protein AZC_2085 from Azorhizobium caulinodans ORS 571 YP_001531777.1 PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein KEGG: sil:SPO0112 poly(3-hydroxyalkanoate) polymerase family protein; high Ref YP hit to poly(3-hydroxyalkanoate) polymerase family protein from Silicibacter pomeroyi DSS-3 and high swissprot hit to Poly(3-hydroxyalkanoate) polymerase (PHA polymerase) from Methylobacterium extorquens; NCBI conserved domains: phaC YP_001531778.1 no significant swissprot, no conserved domains, low Ref Yp hit to uncharacterized conserved coiled coil protein from Marinomonas sp. MWYL1 YP_001531779.1 no significant swissprot, no conserved domains, low Ref YP hit to hypothetical protein SPO0412 from Silicibacter pomeroyi DSS-3 YP_001531780.1 PFAM: C4-dicarboxylate anaerobic carrier KEGG: mes:Meso_2242 C4-dicarboxylate anaerobic carrier; good swissprot hit to Uncharacterized protein HI0594 from Haemophilus influenzae; high Ref Yp hit to C4-dicarboxylate anaerobic carrier from Mesorhizobium sp. BNC1; NCBI conserved domains: dcuC YP_001531781.1 catalyzes the degradation of arginine to citruline and ammonia YP_001531782.1 TIGRFAM: ornithine carbamoyltransferase PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain KEGG: mes:Meso_2240 ornithine carbamoyltransferase; high swissprot hit to Ornithine carbamoyltransferase, catabolic from Haemophilus influenzae YP_001531783.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001531784.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit YP_001531785.1 TIGRFAM: ATP synthase F1, epsilon subunit PFAM: H+transporting two-sector ATPase delta/epsilon subunit KEGG: net:Neut_2014 H+-transporting two-sector ATPase, delta/epsilon subunit, low swissprot hit to ATP synthase epsilon chain 2 from Burkholderia xenovorans LB400 YP_001531786.1 TIGRFAM: F0F1-ATPase subunit, putative PFAM: F0F1-ATPase subunit putative KEGG: net:Neut_2015 F0F1-ATPase subunit, putative; no significant swissprot; low Ref ZP hit to H(+)-transporting ATP synthase, gene 1 from Marinobacter sp. ELB17 YP_001531787.1 no significant swissprot and no conserved domains (except from signalpep. and three transmembr. regions); low, but best Ref ZP hit to F0F1 ATP synthase subunit A from Marinobacter sp. ELB17, lies in the middle of F0F1 ATPase cluster YP_001531788.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001531789.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0 YP_001531790.1 PFAM: H+transporting two-sector ATPase B/B subunit KEGG: net:Neut_2019 H+-transporting two-sector ATPase, B/B subunit; low swissprot hit to ATP synthase B chain from Vibrio vulnificus and good Ref ZP hit to H(+)-transporting ATP synthase, subunit B from Marinobacter sp. ELB17 YP_001531791.1 KEGG: net:Neut_2020 ATP synthase F1, alpha subunit TIGRFAM: ATP synthase F1, alpha subunit PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; high swissprot hit to ATP synthase subunit alpha 2 from Syntrophus aciditrophicus SB YP_001531792.1 PFAM: H+transporting two-sector ATPase gamma subunit KEGG: net:Neut_2021 H+-transporting two-sector ATPase, gamma subunit; low swissprot hit to ATP synthase gamma chain from Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough and good Ref ZP hit to H(+)-transporting ATP synthase, subunit gamma fromMarinobacter sp. ELB17; NCBI conserved domains: atpG YP_001531793.1 no significant swissprot, no conserved domains, low Ref YP hit to hypothetical protein Nham_4077 from Nitrobacter hamburgensis X14 YP_001531794.1 no significant swissprot, no conserved domains, low Ref ZP hit to hypothetical protein NB311A_09431 from Nitrobacter sp. Nb-311A YP_001531795.1 PFAM: CBS domain containing protein; middle Ref YP hit to CBS domain containing protein from Mesorhizobium sp. BNC1 and bad swissprot to Uncharacterized protein yhcV from Bacillus subtilis; NCBI conserved domains: cbs_pair_9 YP_001531796.1 PFAM: cyclic nucleotide-binding SMART: regulatory protein Crp; low swissprot hit to Transcriptional activatory protein aadR from Rhodopseudomonas palustris and middle Ref ZP hit to transcriptional regulator, Crp/Fnr family protein from Roseobacter sp. AzwK-3b; Crp/Fnr family YP_001531797.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; middle swissprot hit to Uncharacterized sensor-like histidine kinase yclK from Bacillus subtilis and high Ref YP hit to Sensor protein resE, putative from Roseobacter denitrificans OCh 114 YP_001531798.1 PFAM: response regulator receiver; transcriptional regulator domain protein; middle swissprot hit to Transcriptional regulatory protein dltR from Streptococcus agalactiae serogroup III (Phosphorylated by dltS kinase); good Ref YP hit to transcriptional regulatory protein PrrA, putative from Roseobacter denitrificans OCh 114; winged helix family YP_001531799.1 Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis; probably provides the glutamate and tyrosine residues that are cross-linked and modified to form the coenzyme YP_001531800.1 possibly involved in transport of pyrroloquinoline quinone transport YP_001531801.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001531802.1 PFAM: coenzyme PQQ synthesis D; low swissprot hit to Coenzyme PQQ synthesis protein D from Silicibacter pomeroyi; middle Ref ZP hit to coenzyme PQQ synthesis protein D from Roseovarius sp. HTCC2601; NCBI conserved domains: pqqD YP_001531803.1 TIGRFAM: coenzyme PQQ biosynthesis protein E PFAM: Radical SAM domain protein KEGG: rde:RD1_1150 coenzyme PQQ biosynthesis protein E; high swissprot hit to Coenzyme PQQ synthesis protein E from Silicibacter pomeroyi YP_001531804.1 no significant swissprot; no conserved domains except for short signalpeptide; high Ref YP hit to hypothetical protein RD1_0870 from Roseobacter denitrificans OCh 114 YP_001531805.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5 SMART: AAA ATPase KEGG: rde:RD1_0871 MoxR-like ATPase, middle swissprot hit to Protein moxR from Methylobacterium extorquens and high Ref YP hit to MoxR-like ATPase from Roseobacter denitrificans OCh 114 YP_001531806.1 PFAM: protein of unknown function DUF58; no significant swissprot; high Ref YP hit to hypothetical protein RD1_0873 from Roseobacter denitrificans OCh 114 YP_001531807.1 no significant swissprot, no conserved domains; middle Ref YP hit to hypothetical protein RD1_0874 from Roseobacter denitrificans OCh 114 YP_001531808.1 PFAM: von Willebrand factor type A KEGG: rde:RD1_0875 hypothetical protein; bad swissprot hit to Uncharacterized protein BB_0173 from Borrelia burgdorferi, unsure GC frame plot YP_001531809.1 no significant swissprot, unsure GC frame plot; NCBI conserved domains: VWA domain (von Willebrand factor); high Ref YP hit to hypothetical protein RD1_0876 from Roseobacter denitrificans OCh 114 YP_001531810.1 unsure GC frame plot, no conserved domains (except for one signalpep. and one transmembr. region); good Ref YP hit to hypothetical protein RD1_0877 from Roseobacter denitrificans OCh 114; bad swissprot hit to Transposon Ty2-GR1 Gag-Pol polyprotein from Saccharomyces cerevisiae; Dshi_0463 transposase family protein YP_001531811.1 no significant swissprot, unsure GC frame plot; high Ref YP hit to hypothetical protein RD1_0878 from Roseobacter denitrificans OCh 114 YP_001531812.1 PFAM: transposase IS3/IS911 family protein KEGG: rde:RD1_3450 inverted repeat region; middle swissprot hit to Insertion element ISR1 uncharacterized 10 kDa protein A3 from Rhizobium sp. YP_001531813.1 PFAM: Integrase catalytic region KEGG: rde:RD1_3449 integrase, catalytic domain, putative; good swissprot hit to Insertion element IS476 uncharacterized 39.2 kDa protein from Xanthomonas euvesicatoria and high Ref YP hit to integrase, catalytic domain, putative from Roseobacter denitrificans OCh 114; NCBI conserved domains: rve YP_001531814.1 blast hits, no swissprot, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, PFAM: regulatory protein LuxR; response regulator receiver; LuxR family YP_001531815.1 PFAM: domain of unknown function DUF1745, no significant swissprot, unsure GC frame plot; high Ref YP hit to hypothetical protein RD1_0880 from Roseobacter denitrificans OCh 114 YP_001531816.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; middle swissprot to Sensor protein rcsC from Salmonella typhimurium; high RefZP hit to putative sensor histidine kinase protein from Sagittula stellata E-37; unsure GC frame plot YP_001531817.1 no significant swissprot; high Ref YP hit to hypothetical protein RD1_0882 from Roseobacter denitrificans OCh 114 YP_001531818.1 no significant swissprot, good ref YP hit to hypothetical protein RD1_0883 from Roseobacter denitrificans OCh 114; no conserved domains (except from signalpep.) YP_001531819.1 PFAM: Sulphur oxidation protein SoxZ ; no significant swissprot; good Ref YP hit to Sulphur oxidation protein SoxZ from Sinorhizobium medicae WSM419; NCBI conserved domains: SoxZ and PRK07474, sulfur oxidation protein SoxY YP_001531820.1 PFAM: beta-lactamase domain protein; KEGG: rde:RD1_0885 hypothetical protein; no significant swissprot, unsure GC frame plot; high Ref YP hit to beta-lactamase domain protein from Sinorhizobium medicae WSM419; NCBI conserved domains: GloB, Zn-dependent hydrolases, including glyoxylases YP_001531821.1 no significant swissprot, no conserved domains, high REf YP hit to hypothetical protein RD1_0886 from Roseobacter denitrificans OCh 114 YP_001531822.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; high swissprot hit to Alcohol dehydrogenase class-3 from Rhodobacter sphaeroides 2.4.1 YP_001531823.1 KEGG: rde:RD1_0888 S-formylglutathione hydrolase, putative TIGRFAM: S-formylglutathione hydrolase PFAM: putative esterase; good swissprot hit to S-formylglutathione hydrolase from Mus musculus; high Ref YP hit to S-formylglutathione hydrolase, putative from Roseobacter denitrificans OCh 114 YP_001531824.1 PFAM: cytochrome c class I; low swissprot hit to Cytochrome c-552 from Paracoccus denitrificans; high Ref YP hit to cytochrome c family protein from Roseobacter denitrificans OCh 114 YP_001531825.1 PFAM: Pyrrolo-quinoline quinone; high swissprot hit to Putative dehydrogenase xoxF precursor from Paracoccus denitrificans; high Ref YP hit to Pyrrolo-quinoline quinone from Rhodobacter sphaeroides ATCC 17025; NCBI conserved domains: pqqDH YP_001531826.1 SSF46626 Cytochrome c, monohaem; NCBI conserved domains: CccA, Cytochrome c, mono- and diheme variants, good swissprot hit to Cytochrome c-553I precursor from Paracoccus denitrificans; good Ref ZP hit to putative cytochrome c protein from Sagittula stellata E-37 YP_001531827.1 SMART: extracellular solute-binding protein family ; NCBI conserved domains: PbPb; low swissprot hit to Protein moxJ precursor from Methylobacterium extorquens (May be involved in the assemblage of active methanoldehydrogenase and/or its cofactor PQQ in the periplasm); high Ref YP hit to putative methanol oxidation protein from Roseobacter denitrificans OCh 114 YP_001531828.1 no significant swissprot, unsure GC frame plot, good gb hit to hypothetical protein RLO149_07849 from Roseobacter litoralis Och 149; NCBI conserved domains: RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein YP_001531829.1 no significant swissprot, unsure GC frame plot; middle gb hit to hypothetical protein RLO149_03449 from Roseobacter litoralis Och 149; no conserved domains detected (except for one signalpep. and transmemb. region) YP_001531830.1 no significant swissprot, high Ref YP hit to hypothetical protein RD1_0894 from Roseobacter denitrificans OCh 114; NCBI conserved domains: COG5501, Predicted secreted protein YP_001531831.1 no significant swissprot, unsure GC frame plot; no conserved domains; good Ref YP hit to hypothetical protein RD1_0897 from Roseobacter denitrificans OCh 114 YP_001531832.1 no significant swissprot, unsure GC frame plot (N-terminal); SSF53822 Periplasmic binding protein-like I; high gb hit to hypothetical protein RLO149_07824 [Roseobacter litoralis Och 149] YP_001531833.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; SSF50969 Quinoprotein amine dehydrogenase, beta chain-like, no significant swissprot, high Ref YP hit to 40-residue YVTN family beta-propeller repeat protein from Sinorhizobium medicae WSM419 YP_001531834.1 no significant swissprot, no conserved domains, high Ref YP hit to hypothetical protein RD1_0900 [Roseobacter denitrificans OCh 114] YP_001531835.1 no significant swissprot, no conserved domains, middle gb hit to hypothetical protein RLO149_07809 [Roseobacter litoralis Och 149]. YP_001531836.1 no significant swissprot; bad Ref XP hit to TPR repeat protein [Entamoeba histolytica HM-1:IMSS]; InterPro Scan: G3DSA:1.25.40.10 Tetratricopeptide-like helical YP_001531837.1 no significant BLAST hits, no conserved domains (except for two transmembr. regions); good RBS site : AGGAT YP_001531838.1 no significant BLAST hits, unsure GC frame plot; NCBI conserved domains: mncomplete BisC domain, Anaerobic dehydrogenases, typically selenocysteine-containing YP_001531839.1 low swissprot hit to Inner membrane protein ybaN from Escherichia coli K12; low Ref YP hit toprotein of unknown function DUF454 from Rhodobacter sphaeroides ATCC 17029; PF04304 Protein of unknown function DUF454; NCBI conserved domains: DUF454, Protein of unknown function (DUF454). Predicted membrane protein; unsure GC frame plot YP_001531840.1 low swissprot hit to Putative aliphatic sulfonates-binding protein precursor from Escherichia coli K12; good Ref YP hit toTwin-arginine translocation pathway signal [Paracoccus denitrificans PD1222]; COG0715 - ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components;TIGR01409 Twin-arginine translocation pathway signal YP_001531841.1 PFAM: binding-protein-dependent transport systems inner membrane component; COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; low swissprot toNitrate transport permease protein nrtB from Phormidium laminosum; high Ref ZP hit toBinding-protein-dependent transport systems inner membrane component [Paracoccus denitrificans PD1222] YP_001531842.1 PFAM: ABC transporter related SMART: AAA ATPase; COG1116 - ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; NCBI conserved domains: ssuB; middle swissprot hit to Aliphatic sulfonates import ATP-binding protein ssuB 1 from Xanthomonas axonopodis pv. citri; good Ref ZP hit to ABC transporter [Paracoccus denitrificans PD1222] YP_001531843.1 PFAM: NnrS family protein KEGG: pde:Pden_4166 NnrS family protein; no swissprot; good gb hit to NnrS [Rhodobacter capsulatus]; NCBI conserved domains: NnrS YP_001531844.1 no significant swissprot; low Ref NP hit to ferrienterobactin-like protein [Agrobacterium tumefaciens str. C58]; Pfam07715 TonB-dependent Receptor Plug Domain YP_001531845.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; no significant swissprot, unsure GC frame plot; high Ref ZP hit to putative ferredoxin [Loktanella vestfoldensis SKA53] YP_001531846.1 no significant swissprot, unsure GC frame plot, no conserved domains; good Ref ZP hit to hypothetical protein SKA53_09144 [Loktanella vestfoldensis SKA53] YP_001531847.1 no significant swissprot; unsure GC frame plot; no conserved domains; good Ref ZP hit to hypothetical protein SKA53_09139 [Loktanella vestfoldensis SKA53] YP_001531848.1 no significant swissprot, unsure GC frame plot; no conserved domains; high Ref ZP hit to hypothetical protein SKA53_09134 [Loktanella vestfoldensis SKA53] YP_001531849.1 no significant swissprot; no conserved domains; unsure GC frame plot; low Ref ZP hit to molybdopterin-guanine dinucleotide biosynthesis protein A from Methylobacterium extorquens PA1 YP_001531850.1 no significant swissprot, no conserved domains; low Ref ZP hit to hypothetical protein SKA53_09124 [Loktanella vestfoldensis SKA53]. YP_001531851.1 PFAM: cytoplasmic chaperone TorD family protein; low swissprot to Chaperone protein torD from Vibrio cholerae and high Ref ZP hit toputative chaperone [Loktanella vestfoldensis SKA53]; NCBI conserved domains: torD YP_001531852.1 no significant swissprot; bad Ref ZP hit to hypothetical protein SKA53_09114 [Loktanella vestfoldensis SKA53]; no conserved domains (except for one transmem. region) YP_001531853.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4; high swissprot hit to Formate dehydrogenase alpha chain from Methanocaldococcus jannaschii; high Ref ZP hit to formate dehydrogenase, alpha subunit, putative [Loktanella vestfoldensis SKA53]; NCBI conserved domains: mopB YP_001531854.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; good swissprot hit to Formate dehydrogenase iron-sulfur subunit from Wolinella succinogenes; high Ref ZP hit to formate dehydrogenase iron-sulfur subunit [Loktanella vestfoldensis SKA53]; NCBI conserved domains: HybA, Fe-S-cluster-containing hydrogenase components 1 YP_001531855.1 TIGRFAM: formate dehydrogenase, gamma subunit; middle swissprot hit to Formate dehydrogenase, nitrate-inducible, cytochrome b556(fdn) subunit (Formate dehydrogenase-N subunit gamma) from Escherichia coli K12; high Ref ZP hit to putative formate dehydrogenase [Loktanella vestfoldensis SKA53]; NCBI conserved domains: fdnI YP_001531856.1 high swissprot hit to Protein mrp homolog from Haemophilus influenzae; high Ref ZP hit to probable multidrug-resistance related protein [Loktanella Loktanella vestfoldensis SKA53]; InterPro Scan: PS01215 Mrp; NCBI conserved domains: mrp-like; ATP/GTP-binding protein YP_001531857.1 PFAM: cytochrome c class I; SMART: WD-40 repeat protein, unsure GC frame plot; low swissprot hit to Cytochrome c from Cochliobolus lunatus; good Ref ZP hit to cytochrome c, class I [Methylobacterium extorquens PA1]; NCBI conserved domains: WD40 YP_001531858.1 no significant swissprot, no conserved domains (except for one signalpep.); unsure GC frame plot; good Ref YP hit to hypothetical protein Spro_3113 [Serratia proteamaculans 568]. YP_003422323.1 good swissprot hit to Alkyl/aryl-sulfatase BDS1 (Bacterially-derived sulfatase 1) from Saccharomyces cerevisiae, high Ref ZP hit to beta-lactamase domain protein [Methylobacterium sp. 4-46];InterPRo Scan: Tetratricopeptide region TPR; NCBI conserved domains: COG2015, Alkyl sulfatase and related hydrolases YP_003422324.1 may be part of Gene Dshi_0510; low swissprot hit to Alkyl/aryl-sulfatase BDS1 (Bacterially-derived sulfatase 1) from Saccharomyces cerevisiae; middle Ref YP hit to metallo-beta-lactamase superfamily protein [Azorhizobium caulinodans ORS 571]; NCBI conserved domains: COG2015, Alkyl sulfatase and related hydrolases; InterPro Scan: no hits reported YP_001531859.1 pfam00753, Lactamase_B, Metallo-beta-lactamase superfamily; COG2333, ComEC, Predicted hydrolase; low swissprot hit to Alkyl/aryl-sulfatase BDS1 (Bacterially-derived sulfatase 1) from Saccharomyces cerevisiae; good Ref YP hit to beta-lactamase domain protein [Polynucleobacter sp. QLW-P1DMWA-1] YP_001531860.1 pfam00196, GerE, Bacterial regulatory proteins, luxR family; low swissprot hit to Transcriptional regulatory protein fixJ from Sinorhizobium meliloti; middle Ref ZP hit to putative two-component response regulator [Roseovarius sp. HTCC2601], unsure GC frame plot; LuxR family YP_001531861.1 bad swissprot to Transcriptional regulatory protein fixJ from Azorhizobium caulinodans; low Ref ZP hit to putative two-component response regulator [Roseovarius sp. HTCC2601]; PFAM00072 response regulator receiver; COG4566, TtrR, Response regulator YP_001531862.1 unsure GC frame plot; - PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; NCBI conserved domains: HisKA; middle swissprot hit to Sensor protein fixL; good Ref ZP hit to probable sensor histidine kinase of two-component system from Roseovarius sp. HTCC2601 YP_001531863.1 pfam04392, ABC_sub_bind, ABC transporter substrate binding protein; no significant swissprot; good Ref ZP hit to probable sensor histidine kinase of two-component system from Roseovarius sp. HTCC2601; unsure GC frame plot YP_001531864.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; COG4213, XylF, ABC-type xylose transport system, periplasmic component; low swissprot hit to D-ribose-binding protein precursor from Bacillus subtilis; High Ref YP Hit to sugar ABC transporter, substrate-binding protein, putative from Roseobacter denitrificans OCh 114; periplasmic component YP_001531865.1 PFAM: inner-membrane translocator; NCBI conserved domains: COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; PRK09512, rbsC, ribose ABC transporter permease protein; middle swissprot hit to Ribose transport system permease protein rbsC from Bacillus subtilis; High gb hit to ribose ABC transporter, permease protein [Roseob; permease components YP_001531866.1 PFAM: ABC transporter related SMART: AAA ATPase, high swissprot to Arabinose import ATP-binding protein araG from Pseudomonas syringae pv. tomato; high gb hit to sugar uptake ABC transporter ATP-binding protein from Roseobacter litoralis Och 149; ATP-binding YP_001531867.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_001531868.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_001531869.1 PFAM: putative sugar-binding domain protein; NCBI conserved domains: pfam04198, Sugar-bind, Putative sugar-binding domain; COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain, good swissprot hit to Uncharacterized transcriptional regulator yjhU from Escherichia coli K12 (related to SorC); high Ref YP hit to transcriptional regulator, putative [Roseobacter denitrificans OCh 114]; DeoR family YP_001531870.1 PFAM: class II aldolase/adducin family protein; COG0235, AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; good swissprot hit to L-fuculose phosphate aldolase from Escherichia coli K12; good Ref ZP hit to L-fuculose phosphate aldolase [Stappia aggregata IAM 12614]; unsure GC frame plot YP_001531871.1 pfam00248: aldo/keto reductase; COG0667, Tas, Predicted oxidoreductases; good swissprot hit to Uncharacterized oxidoreductase yajO from Escherichia coli K12; high Ref NP hit to oxido-reductase, and dehydratase mocA from Mesorhizobium loti MAFF303099 YP_001531872.1 no significant swissprot, unsure GC frame plot; COG3911, Predicted ATPase; cd00009, AAA, AAA-superfamily of ATPases; good Ref ZP hit to ATPase-like protein [Sagittula stellata E-37]. YP_001531873.1 PFAM:PF02734 Dak phosphatase; NCBI conserved domains: PRK10005, dihydroxyacetone kinase, C-terminal domain; low swissprot hit to PTS-dependent dihydroxyacetone kinase, ADP-binding subunit dhaL from Escherichia coli K12; middle Ref ZP hit to Dihydroxyacetone kinase [Psychroflexus torquis ATCC 700755]; unsure GC frame plot; ADP-binding subunit dhaL YP_001531874.1 PFAM: Dak kinase; NCBI conserved domains: PRK11468, dihydroxyacetone kinase subunit DhaK; good swissprot hit to PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit dhaK from Escherichia coli K12; high Ref ZP hit to putative dihydroxyacetone kinase [Aurantimonas sp. SI85-9A1]; dihydroxyacetone-binding subunit dhaK YP_001531875.1 PFAM: inner-membrane translocator; NCBI conserved domains: COG1172, AraH; middle swissprot hit to Ribose transport system permease protein rbsC from Bacillus subtilis; good Ref NP hit to ABC transporter, membrane spanning protein (sugar) [Agrobacterium tumefaciens str. C58]; permease components YP_001531876.1 PFAM: inner-membrane translocator; NCBI conserved domains: COG1172, AraH; middle swissprot hit to Ribose transport system permease protein rbsC from Bacillus subtilis; good Ref ZP hit to putative permease protein, ABC-type sugar transporter [Aurantimonas sp. SI85-9A1]; permease components YP_001531877.1 PFAM: ABC transporter related SMART: AAA ATPase; high swissprot hit to Ribose import ATP-binding protein rbsA 3 from Rubrobacter xylanophilus DSM 9941; high Ref YP hit to ABC transporter related [Nocardioides sp. JS614]; ATP-binding YP_001531878.1 NCBI conserved domains: COG4213, XylF, ABC-type xylose transport system, periplasmic component; low swissprot hit to Uncharacterized protein yneA precursor from Escherichia coli K12; high Ref ZP hit to putative periplasmic substrate-binding protein, ABC-type sugar transporter [Aurantimonas sp. SI85-9A1]; periplasmic component YP_001531879.1 PFAM: putative sugar-binding domain protein; NCBI conserved domains: pfam04198, Sugar-bind and COG2390, DeoR; middle swissprot hit to Deoxyribonucleoside regulator from Bacillus subtilis; good Ref YP hit to transcriptional regulator, DeoR family [Sinorhizobium medicae WSM419]; DeoR family YP_001531880.1 PFAM: Xylose isomerase domain protein TIM barrel; NCBI conserved domains: cd00019, AP2Ec, AP endonuclease family 2; middle swissprot hit to Uncharacterized protein sll1304 from Synechocystis sp. PCC 6803; high Ref YP hit to Xylose isomerase domain protein TIM barrel [Sinorhizobium medicae WSM419] YP_001531881.1 PFAM: dehydrogenase E1 component; good swissprot hit to Pyruvate dehydrogenase E1 component subunit alpha from Zymomonas mobilis; high Ref YP hit to dehydrogenase E1 component [Sinorhizobium medicae WSM419] YP_001531882.1 PFAM: Transketolase central region; Transketolase domain protein; high swissprot hit to Pyruvate dehydrogenase E1 component subunit beta from Rickettsia bellii RML369-C; high Ref YP hit to Transketolase central region [Sinorhizobium medicae WSM419]; Transketolase central region YP_001531883.1 PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; middle swissprot hit to Acetoin dehydrogenase E2 component from Pseudomonas putida; high Ref YP hit to branched-chain alpha-keto acid dehydrogenase subunit E2 from Sinorhizobium medicae WSM419; unsure GC frame plot; pyruvate dehydrogenase E2 component YP_001531884.1 PFAM: carbohydrate kinase FGGY; NCBI conserved domains: AraB, XylB; good swissprot hit to Ribulokinase from Bacillus clausii KSM-K16; high Ref YP hit to carbohydrate kinase FGGY [Sinorhizobium medicae WSM419] YP_001531885.1 unsure GC frame plot; no significant swissprot; PFAM: protein of unknown function DUF1045; high Ref ZP hit to hypothetical protein SSE37_12456 [Sagittula stellata E-37] YP_001531886.1 PFAM: aldo/keto reductase; COG0667, Tas, Predicted oxidoreductases; high Ref ZP hit to oxidoreductase, aldo/keto reductase family protein [Sagittula stellata E-37]; good swissprot hit to Uncharacterized oxidoreductase yajO from Escherichia coli K12; aldo/keto reductase family protein YP_001531887.1 unsure GC frame plot; no significant swissprot; PFAM: NnrUfamily protein; NCBI conserved domains: pfam07298, NnrU, NnrU protein; good Ref ZP hit to NnrU family protein [Roseovarius sp. TM1035] YP_001531888.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001531889.1 NCBI conserved domains: pfam01384, PHO4, Phosphate transporter family; COG0306, PitA, Phosphate/sulphate permeases; high swissprot hit to Putative phosphate permease jhp_1384 from Helicobacter pylori J99; high Ref YP hit to phosphate permease [Azoarcus sp. EbN1]. YP_001531890.1 NCBI conserved domains: pfam02690, Na_Pi_cotrans, Na+/Pi-cotransporter; COG1283, NptA, Na+/phosphate symporter, bad swissprot hit to Na(+)/Pi cotransporter 2B from Bos taurus; high Ref ZP hit to Na+/Pi-cotransporter [Oceanospirillum sp. MED92] YP_001531891.1 no significant BLAST hits, no conserved domains detected YP_001531892.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1 PFAM: Haloacid dehalogenase domain protein hydrolase, NCBI conserved domains: COG0637, Predicted phosphatase/phosphohexomutase; low swissprot hit to Phosphatase yieH from Escherichia coli K12; good gb hit to HAD-superfamily hydrolase subfamily IA, variant 3 [Hoeflea phototrophica DFL-43]; subfamily IA, variant 3 YP_001531893.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein SMART: AAA ATPase; high swissprot hit to sn-glycerol-3-phosphate import ATP-binding protein ugpC from Silicibacter pomeroyi; high gb hit to sorbitol/mannitol ABC transporter, ATP-binding protein [Hoeflea phototrophica DFL-43]; following three ABC transporter genes (Dshi_0547 to Dshi_0549) com YP_001531894.1 PFAM: extracellular solute-binding protein family, NCBI conserved domains: COG1653, UgpB, ABC-type sugar transport system, periplasmic component; low swissprot hit to Putative binding protein BruAb2_0484 precursor from Brucella abortus; high gb hit to sugar ABC transporter, periplasmic binding protein, putative from Hoeflea phototrophica DFL-43; periplasmic component ugpB YP_001531895.1 PFAM: binding-protein-dependent transport systems inner membrane component, NCBI conserved domains: COG1175, UgpA, ABC-type sugar transport systems, permease components; middle swissprot hit to Probable ABC transporter permease protein y4oQ from Rhizobium sp. NGR234; high gb hit to putative sugar ABC transporter, permease protein [Hoeflea phototrophica DFL-43] YP_001531896.1 PFAM: binding-protein-dependent transport systems inner membrane component; NCBI conserved domains: COG0395, UgpE, ABC-type sugar transport system, permease component and COG3833, MalG, ABC-type maltose transport systems, permease component; middle swissprot hit to Probable ABC transporter permease protein y4oR from Rhizobium sp. NGR234; high gb hit to sugar ABC transporter permease protein [Hoef YP_001531897.1 PFAM: putative sugar-binding domain protein; low swissprot hit to Deoxyribonucleoside regulator DeoR from Bacillus subtilis; high gb hit to putative transcriptional regulator protein, DeoR family [Hoefleaphototrophica DFL-43]; DeoR family YP_001531898.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; high swissprot hit to Putative D-xylulose reductase from Sinorhizobium meliloti; high gb hit to D-xylulose reductase, putative [Hoeflea phototrophica DFL-43]; Xylitol dehydrogenase YP_001531899.1 PFAM: sugar isomerase (SIS); middle swissprot to 3-hexulose-6-phosphate isomerase from Bacillus subtilis; good gb hit to 6-phospho-3-hexuloisomerase [Hoeflea phototrophica DFL-43]. YP_001531900.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NCBI conserved domains: PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; middle swissprot hit to3-oxoacyl-[acyl-carrier-protein] reductase from Bacillus subtilis; good ref ZP hit to Short-chain dehydrogenase/reductase SDR [Synechococcus sp. WH 5701] YP_001531901.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; high swissprot hit to Ribitol 2-dehydrogenase (RDH) from Klebsiella aerogenes; high Ref YP hit to probable ribitol 2-dehydrogenase protein [Rhizobium etli CFN 42]. YP_001531902.1 TIGRFAM: FGGY-family pentulose kinase PFAM: carbohydrate kinase FGGY; good swissprot hit to Uncharacterized sugar kinase YDR109C from Saccharomyces cerevisiae; high gb hit to ribitol kinase [Escherichia coli]; unsure Gc frame plot YP_001531903.1 unsure GC frame plot, no significant swissprot, bad gb hit to nucleoside diphosphate kinase regulator from Oceanibulbus indolifex HEL-45; NCBI conserved domains: PRK05753, nucleoside diphosphate kinase regulator YP_001531904.1 PFAM: transcription elongation factor GreA/GreB domain protein, NCBI conserved domains: COG0782, GreA, Transcription elongation factor, bad swissprot hit to Transcription elongation factor greA from Sinorhizobium meliloti; middle gb hit to GreA/GreB family elongation factor [Oceanibulbus indolifex HEL-45]. YP_001531905.1 PFAM: FAD dependent oxidoreductase; NCBI conserved domains: PRK00711, D-amino acid dehydrogenase small subunit; high swissprot hit to D-amino acid dehydrogenase small subunit from Bradyrhizobium japonicum; high gb hit to D-amino-acid dehydrogenase, small subunit protein [Oceanibulbus indolifex HEL-45]. YP_001531906.1 unsure GC frame plot, no significant swissprot, PFAM: protein of unknown function DUF1636; NCBI conserved domains: COG5469, Predicted metal-binding protein; middle Ref ZP hit to hypothetical protein RCCS2_05834 [Roseobacter sp. CCS2]. YP_001531907.1 PFAM: ABC transporter related SMART: AAA ATPase; good swissprot hit to Ferrichrome transport ATP-binding protein fhuC from Escherichia coli K12; high Ref ZP hit to iron ABC transporter, ATP-binding protein, putative [Roseobactersp. CCS2], unsure GC frame plot; ATPase components; alternative gene name: fecE/fepC/btuD YP_001531908.1 PFAM: periplasmic binding protein; low swissprot hit to Vitamin B12-binding protein precursor from Escherichia coli O6; high Ref YP hit to putative iron ABC transporter, periplasmic binding protein from Roseobacter denitrificans OCh 114; NCBI conserved domains: fhuD, btuF; periplasmic binding protein; alternative gene name: fecB/fepB/btuF YP_001531909.1 PFAM: transport system permease protein; NCBI conserved domains: fecCD, fepDG, btuC; good swissprot hit to Ferrichrome transport system permease protein fhuB from Bacillus subtilis; high gb hit to putative hemin ABC transport protein, permease component from Roseobacter litoralis Och 149; permease protein; alternative gene name: fecCD/fepDG/btuC YP_001531910.1 unsure GC frame plot; NCBI conserved domains: COG3487, IrpA, Uncharacterized iron-regulated protein; low swissprot hit to Iron-regulated protein A precursor from Synechococcus elongatus PCC 7942; high Ref ZP hit to lipoprotein, putative [Rhodobacterales bacterium HTCC2150] YP_001531911.1 PFAM: protein of unknown function DUF1111; NCBI conserved domains: COG3488, Predicted thiol oxidoreductase; no significant swissprot; high Ref ZP hit to probable thiol oxidoreductase with 2 cytochrome c heme-binding sites [Sulfitobacter sp. EE-36] YP_001531912.1 low swissprot hit to Iron-regulated protein A precursor from Synechococcus elongatus PCC 7942; high Ref ZP hit to hypothetical protein RB2150_00045 [Rhodobacterales bacterium HTCC2150]; NCBI conserved domains: COG3489, Predicted periplasmic lipoprotein YP_001531913.1 NCBI conserved domains: pfam07433, DUF1513, COG3490, Uncharacterized protein conserved in bacteria, no significant swissprot; high Ref ZP hit to hypothetical protein RB2150_00040 [Rhodobacterales bacterium HTCC2150]; unsure GC frame plot YP_001531914.1 unsure GC frame plot; TIGRFAM: TonB family protein; low swissprot hit to Protein tonB from Pseudomonas putida; low Ref ZP hit toPutative TonB protein [Roseobacter sp. SK209-2-6] YP_001531915.1 PFAM: Biopolymer transport protein ExbD/TolR; low swissprot hit to Biopolymer transport protein exbD1 from Vibrio cholerae; low gb hit to Biopolymer transport protein ExbD/TolR [alpha proteobacterium BAL199] YP_001531916.1 PFAM: MotA/TolQ/ExbB proton channel; low swissprot hit to Putative biopolymer transport protein exbB homolog from Methanothermobacter thermautotrophicus str. Delta H; good Ref ZP hit to MotA/TolQ/ExbB proton channel [Roseobacter sp. SK209-2-6]; NCBI conserved domains: MotA/ ExbB YP_001531917.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; low swissprot hit to Vitamin B12 transporter btuB precursor from Photobacterium profundum; high Ref NP hit to putative outer membrane receptor for iron compound or colicin [Escherichia coli O157:H7 EDL933]; TonB-dependent outermembrane recepter protein; alternative gene name: fecA/fepA/btuB YP_001531918.1 with HmuTU is involved in the transport of hemin YP_001531919.1 PFAM: transport system permease protein; good swissprot hit to Hemin transport system permease protein hmuU from Yersinia pestis; high embl hit to HmuU protein [Rhizobium leguminosarum]. YP_001531920.1 PFAM: periplasmic binding protein; good swissprot hit to Hemin-binding periplasmic protein hmuT precursor from Yersinia pestis; high Ref YP hit to hemin ABC transporter, periplasmic hemin-binding protein [Roseobacter denitrificans OCh 114] YP_001531921.1 PFAM: Haemin-degrading family protein; NCBI conserved domains: hemS; good swissprot hit to Hemin transport protein hmuS fromYersinia pestis; high Ref ZP hit to Haemin-degrading [Roseovarius sp. TM1035]; hemin-degrading YP_001531922.1 no significant swissprot, no conserved domains; low Ref ZP hit to hypothetical protein SSE37_21645 [Sagittula stellata E-37]. YP_001531923.1 PFAM: regulatory protein LysR; LysR substrate-binding; low swissprot hit to Uncharacterized HTH-type transcriptional regulator ydcI from Escherichia coli K12; middle Ref ZP hit to transcriptional regulator, LysR family protein [Roseobacter sp. AzwK-3b]; LysR family YP_001531924.1 PFAM: aldehyde dehydrogenase, NCBI conserved domains: pfam00171, Aldedh, Aldehyde dehydrogenase family; high swissprot hit to Aldehyde dehydrogenase, thermostable from Geobacillus stearothermophilus; high Ref ZP hit to aldehyde dehydrogenase family protein [Roseovarius sp. 217]. YP_001531925.1 PFAM: peptidase M19 renal dipeptidase; NCBI conserved domains: rDP-like; low swissprot hit to Dipeptidase 1 precursor from Oryctolagus cuniculus; high Ref ZP hit to peptidase M19, renal dipeptidase [Roseovarius sp. TM1035] YP_001531926.1 PFAM: BCCT transporter; NCBI conserved domains: COG1292, BetT, Choline-glycine betaine transporter and pfam02028, BCCT; good swissprot hit to Glycine betaine transporter opuD from Bacillus subtilis; high gb hit to putative glycine betaine transporter [Phaeobacter gallaeciensis 2.10] YP_001531927.1 unsure GC frame plot, no significant swissprot, no conserved domains; high Ref ZP hit to hypothetical protein ROS217_07275 [Roseovarius sp. 217] YP_001531928.1 unsure GC frame plot, no significant swissprot, no conserved domains; middle Ref YP hit to hypothetical protein PFL_0797 [Pseudomonas fluorescens Pf-5]. YP_001531929.1 unsure GC frame plot, PFAM: Endoribonuclease L-PSP; NCBI conserved domains: cd02198, YjgH; low swissprot hit to UPF0076 protein HI1627 from Haemophilus influenzae; low Ref YP hit to yjgF family protein [Azorhizobium caulinodans ORS 571]. YP_001531930.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001531931.1 PFAM: lipopolysaccharide biosynthesis protein; NCBI conserved domains: COG3524, KpsE, Capsule polysaccharide export protein; middle swissprot hit to Capsule polysaccharide export inner-membrane protein ctrB from Neisseria meningitidis serogroup A; high Ref ZP hit to Capsule polysaccharide export protein-like [Rhodobacterales bacterium HTCC2150]; permease protein; alternative gene name: ctrB YP_001531932.1 PFAM: ABC transporter related; NCBI conserved domains: kpsT; good swissprot hit to Capsule polysaccharide export ATP-binding protein ctrD from Neisseria meningitidis serogroup B; high Ref ZP hit to capsular polysaccharide export ATP-binding protein [Oceanicola granulosus HTCC2516]; ATP-binding protein; alternative gene name: ctrD YP_001531933.1 PFAM: permease; NCBI conserved domains: COG0701, Predicted permeases; no significant swissprot; high Ref ZP hit to permease, putative [Roseovarius nubinhibens ISM]; ambiguous hits, but in connection with the gene context (Dshi_0584 kpsE, Dshi_0858 kpsT) the permease should be kpsM; permease protein; alternative gene name: ctrC YP_001531934.1 SMART: regulatory protein ArsR; unsure GC frame plot; no significant swissprot; NCBI conserved domains: ArsR; middle Ref ZP hit to transcriptional regulator, ArsR family protein [Roseovarius sp. HTCC2601].; ArsR family YP_001531935.1 unsure GC frame plot; InterPro Scan results: SSF52141 UDNA_glycsylseSF; NCBI conserved domains: COG1573, Uracil-DNA glycosylase and pfam03167, UDG, Uracil DNA glycosylase superfamily; middle swissprot hit to Uncharacterized protein HI0220.2. from Haemophilus influenzae; high Ref YP hit to Uracil-DNA glycosylase superfamily [Jannaschia sp. CCS1]. YP_001531936.1 unsure GC frame plot, no significant swissprot; no conserved domains detected; high Ref ZP hit to hypothetical protein R2601_11544 [Roseovarius sp. HTCC2601] YP_001531937.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; middle swissprot hit to Putative 2-hydroxyacid dehydrogenase ycdW from Escherichia coli K12; high Ref ZP hit to D-isomer specific 2-hydroxyacid dehydrogenase family protein from Roseovarius sp. 217 YP_001531938.1 TIGRFAM: rod shape-determining protein RodA PFAM: cell cycle protein; NCBI conserved domains: COG0772, FtsW, Bacterial cell division membrane protein; good swissprot hit to Rod shape-determining protein rodA from Haemophilus influenzae; high Ref ZP hit to rod shape-determining protein MreD [Roseobacter sp. AzwK-3b]. YP_001531939.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain, NCBI conserved domains: COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2; high swissprot hit to Penicillin-binding protein 2 from Haemophilus influenzae; high Ref ZP hit to penicillin-binding protein 2 [Roseobacter sp. CCS2].; penicillin-binding protein (pbp-2) YP_001531940.1 no significant swissprot; no conserved domains, except from one signalpep. and four transmembr. regions; low Ref ZP hit to putative rod shape-determining protein MreD [Roseobacter sp. CCS2]. YP_001531941.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001531942.1 functions in MreBCD complex in some organisms YP_001531943.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001531944.1 InterPro Scan: G3DSA:2.120.10.30 Six-bladed beta-propeller, TolB-like; NCBI conserved domains: COG3391, Uncharacterized conserved protein; no significant swissprot hit; middle Ref YP hit to hypothetical protein RD1_3731 [Roseobacter denitrificans OCh 114]. YP_001531945.1 PFAM: short-chain dehydrogenase/reductase SDR; NCBI conserved domains: PRK09009, C factor cell-cell signaling protein and PRK06953, short chain dehydrogenase; low swissprot hit to C-factor (C signal) from Myxococcus xanthus; high Ref YP hit to C factor, cell signaling protein, putative [Roseobacter denitrificans OCh 114]. YP_001531946.1 PFAM: deoxyribodipyrimidine photolyase-related protein; NCBI conserved domains: pfam04244, DPRP, Deoxyribodipyrimidine photolyase-related protein and COG0415, PhrB, Deoxyribodipyrimidine photolyase; no significant swissprot; high Ref YP hit to deoxyribodipyrimidine photolyase-related protein [Jannaschia sp. CCS1] YP_001531947.1 PFAM: MORN repeat-containing protein, NCBI conserved domains: several repeats of COG4642, Uncharacterized protein conserved in bacteria; low swissprot hit to Radial spoke head 10 homolog B from Rattus norvegicus; high Ref YP hit to MORN repeat-containing protein [Rhodobacter sphaeroides ATCC Q66HB5] YP_001531948.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001531949.1 PFAM: protein of unknown function DUF1025; NCBI conserved domains: COG3824, Uncharacterized protein conserved in bacteria; bad swissprot hit to Putative metalloprotease XOO2769 from Xanthomonas oryzae pv. oryzae; middle Ref ZP hit to Neutral zinc metallopeptidase [Rhodobacterales bacterium HTCC2654]. YP_001531950.1 PFAM: thioesterase superfamily protein, NCBI conserved domains: cd03442, BFIT_BACH, Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH) and cd03440, hot_dog; middle swissprot hit to Uncharacterized acyl-CoA thioester hydrolase HI0827 from Haemophilus influenzae; middle emb cad hit to acyl-CoA thioester-like hydrolase [Defluvibacter lusatiensis]; unsure GC frame plot YP_001531951.1 PFAM: amidohydrolase 2; CNBI conserved domains: cd01311, PDC_hydrolase, COG2159, Predicted metal-dependent hydrolase, no significant swissprot; unsure GC frame plot; high Ref YP hit to amidohydrolase 2 [Burkholderia multivorans ATCC 17616]. YP_001531952.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; middle swissprot hit to Sialic acid TRAP transporter permease protein siaT from Haemophilus influenzae 86-028NP; high Ref ZP hit to TRAP dicarboxylate transporter, DctM subunit [Shewanella woodyi ATCC 51908]; DctM subunit YP_001531953.1 unsure GC frame plot, no significant swissprot, no conserved domains; low Ref ZP hit to TRAP transporter, transmembrane protein, putative [Roseovarius sp. HTCC2601] YP_001531954.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; NCBI conserved domains: COG1638, DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component; no significant swissprot; good Ref ZP hit to TRAP dicarboxylate transporter- DctP subunit [Shewanella woodyi ATCC 51908] YP_001531955.1 unsure GC frame plot; no significant swissprot; no conserved domains; low Ref YP hit to hypothetical protein TM1040_3278 [Silicibacter sp. TM1040]. YP_001531956.1 unsure GC frame plot; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SSF53383 Pyridoxal phosphate-dependent transferase, major region; good swissprot hit to HTH-type pyridoxine biosynthesis transcriptional regulator pdxR from Corynebacterium glutamicum (position Ser-301 of subject correlates to position Ser-300 of Query in alignment) ; high Ref YP hit to transcriptional regulator, GntR family [Rubrobacter xylanophilus DSM 9941] YP_001531957.1 unsure GC frame plot, good swissprot hit to UPF0317 protein BP1875 from Bordetella pertussis; high gb hit to hypothetical protein HPDFL43_09917 [Hoeflea phototrophica DFL-43] YP_001531958.1 unsure GC frame plot; PFAM: NIPSNAP family containing protein; NCBI conserved domains: NIPSNAP; bad swissprot hit to Protein NipSnap3A from Homo sapiens; low Ref YP hit to NIPSNAP family containing protein [Delftia acidovorans SPH-1]. YP_001531959.1 PFAM: beta-lactamase domain protein; NCBI conserved domains: COG0491, GloB, Zn-dependent hydrolases, including glyoxylases; no significant swissprot; high Ref ZP hit to metallo-beta-lactamase family protein, putative [Roseobacter sp. CCS2] YP_001531960.1 PFAM: band 7 protein; NCBI conserved domains: band_7 and COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs; good swissprot hit to Uncharacterized protein ybbK from Escherichia coli K12; high Ref ZP hit to SPFH domain/band 7 family protein [Sagittula stellata E-37]. YP_001531961.1 PFAM01957 Nodulation efficiency, NfeD; no significant swissprot; low Ref YP hit to hypothetical protein Rsph17025_2810 [Rhodobacter sphaeroides ATCC 17025]. YP_001531962.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001531963.1 unsure GC frame plot, no significant BLAST hits; no conserved domains YP_001531964.1 PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein SMART: AAA ATPase; high swissprot hit to Chaperone protein clpB from Brucella suis; high Ref ZP hit to ATP-dependent Clp protease, ATP-binding subunit ClpB [Roseobacter sp. CCS2]. YP_001531965.1 unsure GC frame plot, no significant swissprot, no conserved domains (except from one signalpep. and two transmem. regions); middle gb hit to hypothetical protein RLO149_06672 [Roseobacter litoralis Och 149]. YP_001531966.1 no significant swissprot, no conserved domains detected; bad Ref ZP hit to SNase-like nuclease [Roseobacter sp. AzwK-3b]. YP_001531967.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NCBI conserved domains: fabG; middle swissprot hit to 3-oxoacyl-[acyl-carrier-protein] reductase from Chlamydia trachomatis; high Ref ZP hit to oxidoreductase [Rhodobacterales bacterium HTCC2150]. YP_001531968.1 PFAM02469 Fasciclin domain; NCBI conserved domains: COG2335, Secreted and surface protein containing fasciclin-like repeats; middle swissprot hit to Uncharacterized protein sll1483 precursor from Synechocystis sp. PCC 6803; middle Ref ZP hit to beta-Ig-H3/fasciclin [Roseovarius sp. TM1035] YP_001531969.1 PFAM02469 Fasciclin domain; NCBI conserved domains: COG2335, Secreted and surface protein containing fasciclin-like repeats; middle swissprot hit to Uncharacterized protein sll1483 precursor from Synechocystis sp. PCC 6803; good Ref ZP hit to beta-Ig-H3/fasciclin [Roseovarius sp. TM1035] YP_001531970.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001531971.1 PFAM: Ferric reductase domain protein transmembrane component domain; NCBI conserved domains: PRK05419, putative sulfite oxidase subunit YedZ, middle swissprot hit to UPF0191 membrane protein yedZ from Escherichia coli O157:H7; good Ref YP hit to putative sulfite oxidase subunit YedZ [Roseobacter denitrificans OCh 114] YP_001531972.1 unsure GC frame plot, no significant BLAST hits YP_001531973.1 PFAM: binding-protein-dependent transport systems inner membrane component; NCBI conserved domains: COG4662, TupA, ABC-type tungstate transport system, periplasmic component; low swissprot hit to Sulfate transport system permease protein cysW from Escherichia coli K12; high Ref ZP hit to sulfate/tungstate uptake family ABC transporter, permease protein from Roseovarius sp. 217; permease protein YP_001531974.1 PFAM: ABC transporter related SMART: AAA ATPase; NCBI conserved domains: cd03260, ABC_PstB_phosphate_transporter; middle swissprot hit to Phosphate import ATP-binding protein pstB from Thermus thermophilus HB27; high Ref ZP hit to sulfate/tungstate uptake family ABC transporter, ATP-binding from Roseovarius sp. 217; ATP-binding protein YP_001531975.1 PFAM: extracellular solute-binding protein family 1, NCBI conserved domains: tupB; no significant swissprot; high Ref ZP hit to sulfate/tungstate uptake family ABC transporter, periplasmic substrate-binding protein from Stappia aggregata IAM 12614; periplasmic substrate-binding protein YP_001531976.1 TIGRFAM: DNA binding domain, excisionase family, NCBI conserved domains: COG1910, Periplasmic molybdate-binding protein/domain; bad swissprot hit to Putative molybdopterin biosynthesis protein MJ0886 from Methanocaldococcus jannaschii; high Ref ZP hit to Periplasmic molybdate-binding protein/domain [Stappia aggregata IAM 12614]. YP_001531977.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001531978.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein, NCBI conserved domains: COG1349, GlpR, Transcriptional regulators of sugar metabolism; high swissprot hit to Glycerol-3-phosphate regulon repressor from Escherichia coli K12; high Ref ZP hit to probable glycerol-3-phosphate regulon repressor [Roseovarius sp. HTCC2601]. YP_001531979.1 TIGRFAM: acetate kinase PFAM: acetate and butyrate kinase KEGG: rde:RD1_3831 acetate kinase; Acetokinase YP_001531980.1 Swissprot: Phosphate acetyltransferase (Phosphotransacetylase) PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase KEGG: rpe:RPE_3163 phosphate butyryltransferase YP_001531981.1 no significant swissprot, no conserved domains; high gb hit to glycosyltransferase, putative [Roseobacter litoralis Och 149]. YP_001531982.1 PFAM: cyclic nucleotide-binding; Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; low swissprot hit to Uncharacterized vacuolar membrane protein YGR125W from Saccharomyces cerevisiae; high Ref YP hit to Sulfate permease and related transporters [Magnetospirillum magneticum AMB-1]. YP_001531983.1 PFAM: phospholipase/Carboxylesterase; NCBI conserved domains: COG0400, Predicted esterase; low swissprot hit to Acyl-protein thioesterase 1 from Yarrowia lipolytica; good gb hit to phospholipase/Carboxylesterase [Roseobacter litoralis Och 149]. YP_001531984.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; NCBI conserved domains: see PFAM result before; middle swissprot hit to Chlorohydroquinone/hydroquinone 1,2-dioxygenase from Sphingomonas paucimobilis; high Ref YP hit to glyoxylase family protein [Roseobacter denitrificans OCh 114] YP_001531985.1 PFAM: ABC transporter related SMART: AAA ATPase; NCBI conserved domains: cd03265, ABC_DrrA; good swissprot hit to Uncharacterized ABC transporter ATP-binding protein yadG from Escherichia coli K12; high gb hit to ABC transporter, ATP-binding protein, putative [Oceanibulbus indolifex HEL-45].; ATP-binding protein YP_001531986.1 PFAM: ABC-2 type transporter, NCBI conserved domains: COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component; good swissprot hit to Inner membrane transport permease yadH from Escherichia coli K12; high Ref ZP hit to ABC transporter, permease protein [Roseobacter sp. SK209-2-6].; permease protein YP_001531987.1 PFAM: peptidase S49; NCBI conserved domains: COG0616, SppA; middle swissprot hit to Putative signal peptide peptidase sppA from Bacillus halodurans; high Ref ZP hit to peptidase S49 [Rhodobacterales bacterium HTCC2150]. YP_001531988.1 no swissprot, no conserved domains, bad Ref ZP hit to hypothetical protein ISM_10031 [Roseovarius nubinhibens ISM]. YP_001531989.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family PFAM: sodium/calcium exchanger membrane region, NCBI conserved domains: COG0530, ECM27, Ca2+/Na+ antiporter; bad swissprot hit to Sodium/potassium/calcium exchanger 1 from Homo sapiens; high Ref ZP hit to K+-dependent Na+/Ca+ exchanger related-protein [Roseobacter sp. AzwK-3b]; CaCA family YP_001531990.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NCBI conserved domains: PRK09134, short chain dehydrogenase; middle swissprot hit to 3-oxoacyl-[acyl-carrier-protein] reductase from Staphylococcus epidermidis ATCC 12228; high Ref ZP hit to short chain dehydrogenase [Roseobacter sp. AzwK-3b]. YP_001531991.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001531992.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; NCBI conserved domains: COG2358, Imp, TRAP-type uncharacterized transport system, periplasmic component; no significant swissprot; high Ref YP hit to TRAP-type uncharacterized transport system, periplasmic component from Hahella chejuensis KCTC 2396; periplasmic component YP_001531993.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; NCBI conserved domains: COG4666, TRAP-type uncharacterized transport system, fused permease componen; bad swissprot hit to Sialic acid TRAP transporter permease protein siaT from Haemophilus influenzae; high Ref ZP hit to TRAP-type uncharacterized transport system, fused permease components [Roseobacter sp. CCS2]. YP_001531994.1 InterPro Scan: Integrin alpha N-terminal domain superfamily; no significant swissprot; low Ref ZP hit to hypothetical protein RED65_02278 [Oceanobacter sp. RED65] YP_001531995.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001531996.1 PFAM: conserved hypothetical protein; NCBI conserved domains: pfam02575, DUF149, Uncharacterised BCR, YbaB family COG0718; low swissprot hit to UPF0133 protein HD_0326 from Haemophilus ducreyi; middle Ref YP hit to conserved hypothetical protein 103 [Jannaschia sp. CCS1]. YP_001531997.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001531998.1 PFAM: NUDIX hydrolase; NADH pyrophosphatase-like ; Zinc ribbon NADH pyrophosphatase; NCBI conserved domains: cd03429, NADH_pyrophosphatase; middle swissprot hit to NADH pyrophosphatase from Escherichia coli O6; high Ref ZP hit to hydrolase, NUDIX family [Loktanella vestfoldensis SKA53]. YP_001531999.1 no significant swissprot; no conserved domains; low Ref ZP hit to hypothetical protein NAS141_10191 [Sulfitobacter sp. NAS-14.1]. YP_001532000.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001532001.1 PFAM: cytochrome c class I; NCBI conserved domains: pfam00034, Cytochrom_C; middle swissprot hit to Cytochrome c-552 from Paracoccus denitrificans; middle Ref ZP hit to cytochrome c552 [Roseobacter sp. AzwK-3b]. YP_001532002.1 PFAM: extracellular solute-binding protein family 5; NCBI conserved domains: COG4166, OppA, ABC-type oligopeptide transport system; high swissprot hit to Uncharacterized protein yejA precursor from Escherichia coli K12; high Ref hit to ABC peptide transporter, substrate binding protein [Rhodobacter sphaeroides 2.4.1].; substrate binding protein; alternative gene name: dppA YP_001532003.1 PFAM: binding-protein-dependent transport systems inner membrane component; NCBI conserved domains: COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; high swissprot hit to Inner membrane ABC transporter permease protein yejB from Escherichia coli K12; high Ref ZP hit to ABC peptide transporter, inner membrane subunit [Sulfitobacter sp. NAS-14.1]; permease protein; alternative gene name: dppBC YP_001532004.1 PFAM: binding-protein-dependent transport systems inner membrane component; NCBI conserved domains: COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; high swissprot hit to Inner membrane ABC transporter permease protein yejE from Escherichia coli K12; high Ref YP hit to ABC peptide transporter, inner membrane subunit [Rhodobacter Rhodobacter sphaeroides 2.4.1]; permease protein; alternative gene name: dppBC YP_001532005.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; NCBI conserved domains: cd03257, ABC_NikE_OppD_transporters; high swissprot hit to Uncharacterized ABC transporter ATP-binding protein yejF from Escherichia coli K12; high Ref ZP hit to peptide ABC transporter, ATP-binding protein, putative [Roseobacter sp. CCS2]; ATP-binding protein; alternative gene name: dppDF YP_001532006.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001532007.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp, NCBI conserved domains: PRK09391, fixK, transcriptional regulator FixK; high swissprot hit to Transcriptional activator protein fnrL from Rhodobacter sphaeroides 2.4.1; high Ref ZP hit to transcriptional activator protein FnrL [Roseovarius sp. 217].; Crp/Fnr family; alternative gene name: fnrL YP_001532008.1 CcoN; FixN YP_001532009.1 CcoO; FixO YP_001532010.1 PFAM: Cbb3-type cytochrome oxidase component; NCBI conserved domains: fixQ; no significant swissprot hit; low Ref ZP hit to cytochrome c oxidase, cbb3-type, subunit IV [Loktanella vestfoldensis SKA53].; cbb3-type, subunit IV YP_001532011.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III PFAM: cytochrome c class I; NCBI conserved domains: COG2010, CccA, Cytochrome c, mono- and diheme variants; high Ref ZP hit to cytochrome c oxidase, cbb3-type, subunit III [Jannaschia sp. CCS1].; cbb3-type, subunit III YP_001532012.1 TIGRFAM: Cytochrome c oxidase cbb3 type accessory protein FixG; PFAM00037 4Fe-4S binding domain; high swissprot hit to Nitrogen fixation protein fixG from Sinorhizobium meliloti; high Ref ZP hit to iron-sulfur-binding protein, RdxA/RdxB/FixG family [Roseobacter sp. AzwK-3b]. YP_001532013.1 PFAM: FixH family protein; NCBI conserved domains: fixH; low swissprot hit to Nitrogen fixation protein fixH from Sinorhizobium meliloti, middle Ref ZP hit to FixH [Silicibacter sp. TM1040]. YP_001532014.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; high swissprot hit to Nitrogen fixation protein fixI from Sinorhizobium meliloti; high Ref ZP hit to copper-t; E1-E2 type cation ATPase fixI YP_001532015.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type PFAM: cytochrome oxidase maturation protein cbb3-type; NCBI conserved domains: fixS, ccoS; low swissprot hit to Nitrogen fixation protein fixS from Sinorhizobium meliloti; low Ref YP hit to cytochrome oxidase maturation protein, cbb3-type [Rhodobacter sphaeroides ATCC 17025]. YP_001532016.1 PFAM: beta-lactamase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; NCBI conserved domains: dacC; middle swissprot hit to D-alanyl-D-alanine carboxypeptidase dacC precursor from Escherichia coli K12; high Ref YP hit to D-alanyl-D-alanine carboxypeptidase family protein [Roseobacter denitrificans OCh 114]. YP_001532017.1 ibu; PFAM: Haloacid dehalogenase domain protein hydrolase; NCBI conserved domains: COG1011, Predicted hydrolase (HAD superfamily); bad swissprot hit to Uncharacterized HAD-hydrolase MTH_209 from Methanothermobacter thermautotrophicus str. Delta H; high Ref YP hit to Haloacid dehalogenase domain protein hydrolase [Rhodobacter sphaeroides ATCC 17025]. YP_001532018.1 PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; NCBI conserved domains: rsmC; low swissprot hit to Ribosomal RNA small subunit methyltransferase C from Escherichia coli K12; high Ref ZP hit to Possible ribosomal RNA small subunit methyltransferase C RsmC from Roseobacter sp. CCS2 YP_001532019.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; low swissprot hit to 7-alpha-hydroxysteroid dehydrogenase from Escherichia coli K12; high Ref ZP hit to 7-alpha-hydroxysteroid dehydrogenase, putative [Roseovarius nubinhibens ISM]. YP_001532020.1 no significant swissprot, no conserved domains; bad Ref ZP hit to hypothetical protein RTM1035_19081 [Roseovarius sp. TM1035]. YP_001532021.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001532022.1 TIGRFAM: gamma-glutamyltransferase PFAM: gamma-glutamyltranspeptidase; NCBI conserved domains: ggT; high swissprot hit to Gamma-glutamyltranspeptidase precursor from Escherichia coli K12; high Ref YP hit to Gamma-glutamyltransferase [Jannaschia sp. CCS1]. YP_001532023.1 PFAM: beta-lactamase; NCBI conserved domains: COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins; bad swissprot hit to Penicillin-binding protein 4* (PBP 4*) from Bacillus subtilis; bad Ref YP hit to beta-lactamase [Chloroflexus aurantiacus J-10-fl] YP_001532024.1 Pfam03567 Sulfotransferase; NCBI conserved domains: pfam03567; bad swissprot hit to Carbohydrate sulfotransferase 9 from Mus musculus; high Ref ZP hit to hypothetical protein R2601_13619 [Roseovarius sp. HTCC2601]. YP_001532025.1 PFAM: glycosyl transferase family 14; NCBI conserved domains: pfam02485, Branch, Core-2/I-Branching enzyme, pfam03267, DUF266, Domain of unknown function, bad swissprot hit to Xylosyltransferase from Ciona intestinalis; high Ref YP hit to epsK domain protein [Silicibacter pomeroyi DSS-3]. YP_001532026.1 PFAM: histidine triad (HIT) protein; NCBI conserved domains: cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI), COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; middle swissprot hit to Uncharacterized 13.2 kDa HIT-like protein in hisE 3region from Azospirillum brasilense; good Ref ZP hit to HIT-like protein, putative [Roseobacter sp. AzwK-3b]. YP_001532027.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001532028.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; NCBI conserved domains: purE; middle swissprot hit to Phosphoribosylaminoimidazole carboxylase catalytic subunit from Bacillus subtilis; high Ref YP hit to Phosphoribosylaminoimidazole carboxylase, catalytic subunit from Rhodobacter sphaeroides 2.4.1; catalytic subunit YP_001532029.1 PFAM: protein of unknown function DUF465; no significant swissprot; low Ref ZP hit to Protein of unknown function DUF465 [Paracoccus denitrificans PD1222]. YP_001532030.1 PFAM: heat shock protein Hsp20; NCBI conserved domains: ibpA; low swissprot hit to Small heat shock protein ibpA from Salmonella choleraesuis; good Ref YP hit to heat shock protein Hsp20 [Jannaschia sp. CCS1]. YP_001532031.1 NCBI conserved domains: pfam06620 DUF1150, Protein of unknown function, COG5568, Uncharacterized small protein; no significant swissprot; low Ref ZP hit to hypothetical protein OB2597_07215 [Oceanicola batsensis HTCC2597]. YP_001532032.1 PFAM: ApbE family lipoprotein KEGG: pde:Pden_2485 ApbE family lipoprotein YP_001532033.1 InterPro Scan: PIRSF036354 nitrous oxide reductase expression regulator NosR; NCBI conserved domains: nosR; high swissprot hit to Regulatory protein nosR from Pseudomonas stutzeri; high Ref ZP hit to regulatory protein, putative [Sagittula stellata E-37]. YP_001532034.1 PFAM: binding-protein-dependent transport systems inner membrane component; NCBI conserved domains: COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; low swissprot hit to Putative aliphatic sulfonates transport permease protein ssuC from Bacillus subtilis; high Ref ZP hit to putative ABC transporter protein [Sagittula stellata E-37]; other two ABC-transporter components (ATP-binding, substrate-binding) are missing YP_001532035.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NCBI conserved domains: PRK06481, fumarate reductase flavoprotein subunit, COG1053, SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; middle swissprot hit to Fumarate reductase flavoprotein subunit precursor from Shewanella oneidensis; high Ref YP hit to fumarate reductase/succinate dehydrogenase flavoprotein-like from Jannaschia sp. CCS1 YP_001532036.1 NCBI conserved domains: COG2513, PrpB, PEP phosphonomutase and related enzymes; PRK11320, prpB, 2-methylisocitrate lyase; middle swissprot hit to Methylisocitrate lyase from Vibrio cholerae; high Ref YP hit to isocitrate lyase family protein [Jannaschia sp. CCS1]. YP_001532037.1 PFAM: isochorismatase hydrolase; NCBI conserved domains: COG1535, EntB, Isochorismate hydrolase; low swissprot hit to Isochorismatase (Isochorismate lyase) from Escherichia coli K12; high Ref ZP hit to isochorismatase family protein [Sulfitobacter sp. EE-36]. YP_001532038.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; NCBI conserved domains: COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit; high swissprot hit to Hydantoin utilization protein A from Pseudomonas sp. NS671; high Ref ZP hit to hydantoin utilization protein A [Roseovarius sp. HTCC2601]. YP_001532039.1 PFAM: Hydantoinase B/oxoprolinase, NCBI conserved domains: COG0146, HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit; good swissprot hit to Hydantoin utilization protein B from Pseudomonas sp. NS671; high Ref ZP hit to hydantoin utilization protein B, putative [Roseovarius sp. HTCC2601]. YP_001532040.1 PFAM: 4-oxalocrotonate tautomerase; NCBI conserved domains: pfam01361, Tautomerase; no significant swissprot, good Ref ZP hit to tautomerase, putative [Loktanella vestfoldensis SKA53]. YP_001532041.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; NCBI conserved domains: pfam07702, UTRA; low swissprot hit to Uncharacterized HTH-type transcriptional regulator yidP from Escherichia coli K12; high Ref YP hit to transcriptional regulator, GntR family [Jannaschia sp. CCS1].; GntR family YP_001532042.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001532043.1 TIGRFAM: 3-isopropylmalate dehydratase, small subunit PFAM: aconitate hydratase domain protein; NCBI conserved domains: PRK01641, leuD, isopropylmalate isomerase small subunit; good swissprot hit to 3-isopropylmalate dehydratase small subunit from Symbiobacterium thermophilum; good Ref ZP hit to 3-isopropylmalate dehydratase, small subunit [Sulfitobacter sp. NAS-14.1]. YP_001532044.1 PFAM: TRAP dicarboxylate transporter- DctP subunit, NCBI conserved domains: COG1638, DctP; bad swissprot hit to C4-dicarboxylate-binding periplasmic protein precursor from Rhodobacter capsulatus; high Ref ZP hit to TRAP dicarboxylate transporter- DctP subunit [Hoeflea phototrophica DFL-43]. YP_001532045.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component, NCBI conserved domains: dctQ and dctM small permease component; no significant swissprot; good Ref ZP hit to TRAP dicarboxylate transporter, DctQ subunit, putative from Sulfitobacter sp. EE-36 YP_001532046.1 PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; NCBI conserved domains: COG4664, FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component and dctMQ; middle swissprot hit to Putative TRAP transporter large permease protein HI0050 from Haemophilus influenzae; high Ref ZP hit to TRAP dicarboxylate transporter, DctM subunit [Loktanella vestfoldensis SKA53]. YP_001532047.1 PFAM: AMP-dependent synthetase and ligase; NCBI conserved domains: COG0318, CaiC, Acyl-CoA synthetases (AMP-forming); middle swissprot hit to 2-succinylbenzoate--CoA ligase (OSB-CoA synthetase) from Bacillus anthracis; high Ref ZP hit to AMP-binding enzyme [Rhodobacterales bacterium HTCC2654]. YP_001532048.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; NCBI conserved domains: COG2226, UbiE; no significant swissprot; middle Ref YP hit to Methyltransferase type 12 [Flavobacterium johnsoniae UW101] YP_001532049.1 InterPro Scan and NCBI conserved domains: pfam08889, WbqC; no significant swissprot; low gb hit to WbnG [Shigella dysenteriae]. YP_001532050.1 NCBI conserved domains: pfam00535, Glycos_transf_2, Glycosyl transferase family 2; no significant swissprot; low Ref YP hit to hypothetical protein Rsph17025_3846 [Rhodobacter sphaeroides ATCC 17025]. YP_001532051.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aminotransferase class-III; NCBI conserved domains: pfam01041, DegT_DnrJ_EryC1, DegT/DnrJ/EryC1/StrS aminotransferase family; COG0399, WecE, Predicted pyridoxal phosphate-dependent enzyme; low swissprot hit to UDP-Ara4O aminotransferase from Salmonella typhi; middle Ref YP hit to DegT/DnrJ/EryC1/StrS aminotransferase [Methylobacillus flagellatus KT] YP_001532052.1 NCBI conserved domains: COG4421, Capsular polysaccharide biosynthesis protein; no significant swissprot; low Ref ZP hit to Capsular polysaccharide biosynthesis protein-like protein from Roseobacter sp. AzwK-3b YP_001532053.1 NCBI conserved domains: cd00208, LbetaH, Left-Handed Parallel beta-Helix and COG1044, LpxD, UDP-3-O-[3-hydroxymyristoyl]; low swissprot hit to UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase from Nitrosococcus oceani ATCC 19707; middle Ref ZP hit to transferase hexapeptide repeat [Pseudomonas putida W619] YP_001532054.1 unsure GC frame Plot, no conserved domains; no significant swissprot; middle Ref YP hit to hypothetical protein BTH_I3215 [Burkholderia thailandensis E264]. YP_001532055.1 PFAM: coenzyme A transferase; NCBI conserved domains: atoDA; low swissprot hit to SCOT-S from Sus scrofa; high Ref ZP hit to Coenzyme A transferase [Roseobacter litoralis Och 149]. YP_001532056.1 no significant swissprot; no conserved domains detected (except from one signalpep. and six transmembr. regions); middle Ref ZP hit to hypothetical protein RLO149_12985 [Roseobacter litoralis Och 149]. YP_001532057.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001532058.1 NCBI conserved domains: COG1279, Lysine efflux permease; pfam01810, LysE; middle swissprot hit to Putative amino-acid transporter yggA from Aeromonas salmonicida; good Ref ZP hit to L-lysine exporter, putative [Oceanibulbus indolifex HEL-45].; LYSE/YGGA YP_001532059.1 NCBI conserved domains: COG3509, LpqC; no significant swissprot; low REf YP hit to polyhydroxybutyrate depolymerase [Frankia sp. EAN1pec]. YP_001532060.1 NCBI conserved domains: pfam00892, DUF6, Integral membrane protein DUF6; COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily; low swissprot hit to S-adenosylmethionine uptake transporter from Rickettsia typhi; high Ref ZP hit to membrane protein, putative [Roseobacter sp. MED193]. YP_001532061.1 PFAM04325 Protein of unknown function (DUF465); NCBI conserved domains: COG2841, Uncharacterized protein conserved in bacteria; no swissprot hit; low Ref YP hit to protein of unknown function DUF465 [Silicibacter sp. TM1040]. YP_001532062.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; NCBI conserved domains: COG3800, Predicted transcriptional regulator; no significant swissprot; high Ref YP hit to transcriptional regulator, XRE family [Silicibacter sp. TM1040].; XRE (HTH-3) family YP_001532063.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily PFAM: major facilitator superfamily MFS_1, NCBI conserved domains: PRK11652, emrD, multidrug resistance protein D; low swissprot hit to Bicyclomycin resistance protein (bcr) from Escherichia coli K12; high Ref ZP hit to MFS protein, putative [Roseobacter sp. AzwK-3b]. YP_001532064.1 Probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. YP_001532066.1 Active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. YP_001532067.1 weak similarity to genes in Rhodobacteraceae YP_001532068.1 conserved in Rhodobacteraceae and Bradyrhizobiaceae YP_001532069.1 biotin-dependent enzyme, Probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. YP_001532072.1 MDM; functions in conversion of succinate to propionate YP_001532073.1 HTH and substrate binding domain; LysR family YP_001532076.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001532078.1 Members of the PhaE/MrpE family are predicted to be integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaE is part of a potassium efflux system involved in pH regulation YP_001532079.1 Members of the PhaF/MrpF family are predicted to be integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation YP_001532080.1 family of small, transmembrane proteins believed to be components of Na+/H+ and K+/H+ antiporters. Members, including proteins designated MnhG from Staphylococcus aureus and PhaG from Rhizobium meliloti, show some similarity to chain L of the NADH dehydrogenase I, which also translocates protons.; MnhG/PhaG subunit YP_001532082.1 protein N-Acetyl-transferase YP_001532085.1 This family consists of the N-terminal region of exopolyphosphatase (Ppx) and guanosine pentaphosphate phospho-hydrolase (GppA). YP_001532086.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001532087.1 weak evidence for predicted function; DnaA YP_001532088.1 predicted transmembrane protein (10TMH) YP_001532089.1 Mechanosensitive (MS) channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation. YP_001532090.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001532091.1 This family of redoxins includes peroxiredoxin, thioredoxin and glutaredoxin proteins. YP_001532092.1 Transport of water across the membrane. YP_001532093.1 Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane.; transmembrane protein, LolC/E family YP_001532094.1 Part of the ABC transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, lolA. Responsible for the formation of the lolA-lipoprotein complex in an ATP-dependent manner YP_001532095.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001532097.1 Protein with ppk2 Domain, cytoplasmatic YP_001532098.1 contains DUF1007 domain YP_001532099.1 incorporation of nickel into H2-uptake hydrogenase and urease, signal peptide cleveage after AA 22, inner membrane YP_001532100.1 SAM-dependent methyltransferase, Substrate not known KEGG: rsp:RSP_0765 SAM-dependent methyltransferase YP_001532104.1 MarR family YP_001532107.1 conserved in Rhodobacteraceae YP_001532108.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001532109.1 Helix-Turn-Helix motif; XRE family YP_001532111.1 HTH domain; MarR family YP_001532112.1 putative lipoprotein YP_001532113.1 Lactoylglutathione lyase YP_001532114.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_001532115.1 CSD(cold shock DNA-binding) domain containing Protein, binds single stranded DNA, 4 homologs in E. coli cspABCD YP_001532116.1 conserved arsC domain YP_001532120.1 predicted inner membrane protein, conserved in Rhodobacteraceae YP_001532121.1 multiple catalytic activities: EC:1.1.1.93: Tartrate + NAD(+) <=> oxaloglycolate + NADH; EC:4.1.1.73: (R,R)-tartrate <=> D-glycerate + CO2; EC:1.1.1.83: (R)-malate + NAD(+) <=> pyruvate + CO(2) + NADH; cytoplasmatic; Belongs to the isocitrate and isopropylmalate dehydrogenases family YP_001532122.1 similar to ppaA in the photosynthetic gene cluster, cytosolic YP_001532123.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001532125.1 protein with 2 functional domains: MarR and acetyltransferase (GNAT); MarR family with acetyltransferase activity YP_001532126.1 Hydrolase, alpha/beta fold motiv with catalytic triade YP_001532127.1 contains SCP-2 sterol transfer family domain YP_001532128.1 putative Tetratricopeptide TPR_2 repeat protein YP_001532129.1 contains Helicase domain YP_001532131.1 contains [3Fe-4S] and [4Fe-4S] Cys cluster YP_001532132.1 similar to N-terminus of M. xanthus carD protein; CarD family YP_001532133.1 Cobalamin biosynthesis, Reaction: Cobamide coenzyme + GMP <=> Adenosine-GDP-cobinamide + alpha-Ribazole YP_001532134.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001532135.1 glutathione regulated, K+/H+ antiporter, NAD-binding domain YP_001532136.1 conserved in Rhodobacteraceae YP_001532137.1 protein of unknown function DUF541, bacterial membrane or periplasm protein YP_001532139.1 PLP-dependent, Reaction: O-Acetyl-L-homoserine + Methanethiol <=> L-Methionine + Acetate, Also reacts with other thiols and H2S, producing homocysteine or thioethers YP_001532140.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001532141.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001532142.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001532143.1 weakly conserved GCN5-related N-acetyltransferase, possibly EC:3.5.1.16 YP_001532144.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001532146.1 Helix-Turn-Helix motiv, iclR subfamily; IclR family YP_001532147.1 TRAP gene cluster - dctPQM YP_001532148.1 TRAP gene cluster - dctPQM YP_001532149.1 TRAP gene cluster - dctPQM YP_001532150.1 contains N- and C-terminal GMC-oxidoreductase domain, FAD-binding YP_001532151.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_001532152.1 9 potential transmembrane domains YP_001532154.1 integrates membrane bound lytic transglycosylase and penicillin-binding protein into a complex YP_001532155.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001532158.1 TraR/DksA family YP_001532159.1 2 predicted transmembrane domains YP_001532160.1 conserved in Rhodobacteraceae and Bradyrhizobiaceae YP_001532161.1 catalyzes the first step of the glyoxal pathway YP_001532166.1 hydrolase, alpha/beta fold motif with catalytic triade YP_001532167.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001532168.1 catalyzes the phosphorylation of NAD to NADP YP_001532169.1 Transcriptional regulater, ATP dependent Sigma54 interaction, part of two component system; Fis family YP_001532170.1 C-Terminal domain of arcB (aerobic respiration control), no PAS domain (sensor) YP_001532171.1 AMP-binding domain, ligase similar to propionate-CoA and Acetyl-CoA ligase YP_001532172.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate YP_001532173.1 Reaction: Cytidine + H2O <=> Uridine + NH3 YP_001532174.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001532175.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001532176.1 catalyzes the formation of inosine from adenosine YP_001532177.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001532178.1 conserved in Rhodobacteraceae YP_001532179.1 putative Acyl-CoA-Ligase (inferred from Swiss-Prot) YP_001532180.1 contains 1 N-terminal DUF6-domain YP_001532181.1 multifunctional enzyme: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase, Reaction: (3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O, Reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA; 3-hydroxyacyl-CoA dehydrogenase, Reaction(EC:1.1.1.35):(3S)-3-Hydroxyacyl-CoA + NAD+ <=> 3-Oxoacyl-CoA + NADH + H+ YP_001532182.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001532183.1 not all GST-like proteins show catalytic activity YP_001532184.1 contains all Acyl-CoA dehydrogenase domains; Reaction: Acyl-CoA + Acceptor <=> 2,3-Dehydroacyl-CoA + Reduced acceptor YP_001532185.1 Oxidoreductase acting on the CH-CH group of donors with other acceptors YP_001532186.1 contains winged helix DNA-binding motif; MerR family YP_001532188.1 contains winged helix DNA-binding motif; MerR family YP_001532191.1 contains two multi antimicrobial extrusion (MATE) domains, drug/sodium antiporter YP_001532192.1 related to glutaredoxins, Reaction: Arsenate ion + Glutaredoxin <=> Arsenite + Glutaredoxin disulfide YP_001532193.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001532194.1 hypothetical bacterial and plant proteins of unknown function YP_001532195.1 membrane bound, hydrolyzes extracellular nucleotides into membrane permeable nucleosides, Reaction: 5-Ribonucleotide + H2O <=> Ribonucleoside + Orthophosphate YP_001532196.1 he DEAD box helicases are involved in various aspects of RNA metabolism YP_001532197.1 contains DUF159 domain YP_001532198.1 ABC transporter with fused ATPase and inner membrane subunits, Involved in lipid A export and inner membrane biogenesis; fused ATPase and inner membrane subunits YP_001532199.1 esterification and transport of exogeneous long chain fatty acids, Reaction: ATP + a long-chain carboxylic acid + CoA <=> AMP + diphosphate + an acyl-CoA YP_001532201.1 belongs to class of conserved hypothetical proteins with N-terminal transglutaminse domain, catalytic activity not proofed YP_001532202.1 contains DUF404, 407, 403 domains YP_001532203.1 belongs to clas of conserved hypothetical proteins with N-terminal transglutaminse domain, catalytic activity not proofed YP_001532204.1 ABC transporter (importer) gene cluster: 2nd ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532205.1 ABC transporter (importer) gene cluster: 1st ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532206.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532207.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532208.1 ABC transporter (importer) gene cluster: receptor YP_001532209.1 helix-turn-helix DNA-binding motif; AsnC family YP_001532210.1 putative oxidoreductase YP_001532211.1 function not clear, similar to several Swiss-Prot curated proteins YP_001532212.1 Hydrolase, alpha/beta fold motiv with catalytic triade, weak evidence YP_001532213.1 contains amidohydrolase 2 domain YP_001532214.1 peptidase related (trEMBL) YP_001532215.1 phosphoesterase related (trEMBL) YP_001532216.1 weak similarity to transcriptional regulator, SARP family, TPR repeats; SARP family YP_001532218.1 ABC transporter (importer) gene cluster: receptor (cluster disrupted) YP_001532220.1 part of extracellular ligand-binding receptor; family 5 YP_001532223.1 ABC transporter (importer) gene cluster: receptor, N-terminal truncated YP_001532226.1 involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds YP_001532227.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532228.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532230.1 ABC transporter (importer) gene cluster: 1st ATP binding cassette (ABC) domain; part of a heterotetramer; ATPase subunit YP_001532231.1 ABC transporter (importer) gene cluster: 2nd ATP binding cassette (ABC) domain; part of a heterotetramer; ATPase subunit YP_001532232.1 Helix-Turn-Helix motif, iclR subfamily; IclR family YP_001532233.1 PLP-dependent enzyme, Reaction: L-serine + glyoxylate <=> 3-hydroxypyruvate + glycine YP_001532234.1 PLP dependnet enzyme, catalytic activity not clear, Swiss-Prot hits to serine racemase, threonine dehydratase YP_001532235.1 contains N-terminal domain of alanine racemase, C-terminal domain missing YP_001532236.1 catalyses the deamination of ornithine to proline, Reaction: L-Ornithine <=> L-Proline + NH3 YP_001532237.1 PLP-dependent Enzyme, Reaction: O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate YP_001532239.1 inner membrane protein YP_001532240.1 inner membrane protein YP_001532243.1 Salmonella: activated by the global signal transduction/regulatory system SsrA/B, when in eukaryotic cells YP_001532247.1 ABC transporter (importer) gene cluster (disrupted): ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532248.1 ABC transporter (importer) gene cluster (disrupted): membrane spanning domain (MSD); part of a heterotetramer YP_001532250.1 conserved only in R. denitrificans YP_001532251.1 membrane protein, contains a pair of UPF0126 domains YP_001532252.1 ABC transporter (importer) gene cluster: membrane spanning domain (MSD); part of a heterotetramer YP_001532253.1 ABC transporter (importer) gene cluster: 1st ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532254.1 involved in thiamine biosynthesis; TenA family YP_001532255.1 ABC transporter (importer) gene cluster: receptor, NMT1/THI5 like domain, involved in Thiamine biosynthesis YP_001532256.1 contains thiF and MoeZ/B-domain YP_001532257.1 Magnesium dependent, Reaction: 2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-Methyl-5-(2-phosphoethyl)-thiazole <=> Pyrophosphate + Thiaminmonophosphate YP_001532258.1 Required for the synthesis of the thiazole moiety of thiamine YP_001532259.1 involved in sulphur transfer YP_001532260.1 FAD dependent oxidoreductase, active with glycine, sarcosine, N-ethylglycine, D-alanine, D-alpha-aminobutyrate, D-proline, D-pipecolate and N-methyl-D-alanine YP_001532261.1 cofactor biosynthesis, Reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine <=> ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001532262.1 RND transporters are involved in multidrug resistance and heavy metal resistance. The resistance is performed by H+ driven export of the toxic compounds.; RND family, MFP subunit YP_001532263.1 RND transporters are involved in multidrug resistance, heavy metal resistance. The resistance is performed by H+ driven export of the toxic compounds. YP_001532264.1 belongs to a mostly uncharacterised family of membrane transport proteins found in eukaryotes, bacteria and archaea YP_001532265.1 Metallo-beta-lactamase superfamily, apart from the beta-lactamases a number of other proteins contain this domain YP_001532266.1 related to a large superfamily of metalloenzymes, TatD, a member of this family has been shown experimentally to be a DNase enzyme; TatD family YP_001532267.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001532268.1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis, Reaction: ATP + dTMP <=> ADP + dTDP YP_001532269.1 Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors, Preferential cleavage: (Ac)2-L-Lys-D-Ala-D-Ala YP_001532270.1 contains SPOR domain, involved in binding peptidoglycan YP_001532271.1 weak conservation YP_001532274.1 inner membrane protein YP_001532275.1 contains 2 UspA domains, expression is enhanced when the cell is exposed to stress agents, enhances the rate of cell survival during prolonged exposure to such conditions YP_001532276.1 Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells YP_001532277.1 zinc-containing alcohol dehydrogenase family, Reaction: An alcohol + NAD+ <=> an aldehyde or ketone + NADH YP_001532278.1 members of this ATPase-family are involved in Na+/K+, H+/K+, Ca++ and Mg++ transport; P-type (transporting), HAD superfamily, subfamily IC YP_001532279.1 weak evidence for function as DNA binding domain, excisionase family; excisionase family YP_001532282.1 exported or inner-membrane bound, catalyzes hydrolization of sulfate from organic compounds YP_001532284.1 helix-turn-helix DNA-binding motif; AraC family YP_001532285.1 28aa of a transposase orfA IS5 family element (normally about 100-120aa) YP_001532288.1 Members of the M23 peptidase family are zinc-metallopeptidases, most are endopeptidases, inner membrane location: possible function as cell wall peptidase YP_001532289.1 contains CAAX amino terminal protease domain YP_001532290.1 putative transmembrane protein (PSORT) YP_001532291.1 contains C-terminal putative peptidoglycan-binding domain, found in metalloproteases, N-terminus not characterized YP_001532292.1 conserved in bacteria YP_001532293.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001532294.1 FMN-dependent dehydrogenase, Reaction: (S)-lactate + 2 ferricytochrome c <=> pyruvate + 2 ferrocytochrome c + 2 H+; cytochrome YP_001532296.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001532298.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001532299.1 contains two multi antimicrobial extrusion (MATE) domains, drug/sodium antiporter YP_001532300.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001532301.1 similar to predicted racemases YP_001532302.1 TRAP gene cluster - dctPQM; DctM subunit YP_001532303.1 TRAP gene cluster - dctPQM YP_001532304.1 TRAP gene cluster - dctPQM; DctP subunit YP_001532305.1 helix-turn-helix DNA-binding motif, SIS domain, found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; RpiR family YP_001532306.1 N-terminal HTH region, C-terminal FCD effector binding domain; GntR family YP_001532307.1 C-terminal domain is missing, probable pseudogene YP_001532310.1 FAA is the last enzyme in the tyrosine catabolic pathway YP_001532311.1 The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat YP_001532312.1 Reaction: D-mannitol + NAD+ <=> D-fructose + NADH YP_001532313.1 N-terminal truncated YP_001532314.1 ABC transporter (importer) gene cluster: 1st ATP binding cassette (ABC) domain; part of a heterotetramer, no second ABC domain protein, single TOBE domain YP_001532315.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532316.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532317.1 ABC transporter (importer) gene cluster: receptor YP_001532318.1 LacI family YP_001532320.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001532321.1 conserved in alphaproteobacteria YP_001532322.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001532323.1 conserved uncharacterized protein YP_001532324.1 function not clear, homology to protein tyrosine phosphatase and arsenate reductase YP_001532325.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001532326.1 putative inhibitor of septum formation YP_001532327.1 Ribonuclease G and E-like family YP_001532329.1 DNA-binding, putative transcriptional regulator YP_001532330.1 conserved in bacteria YP_001532331.1 Phage integrase proteins cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment YP_001532335.1 protects the organism against invading foreign DNA, part of a heteromeric enzyme complex, mod (modification methyltransferase)subunit is missing YP_001532336.1 TRAP gene cluster - dctPQM; TAXI family YP_001532337.1 TRAP gene cluster - dctPQM; 4TM/12TM fusion protein YP_001532338.1 contains substrate binding domain, putative homotetramer; LysR family YP_001532339.1 subunit of NADH dehydrogenase, electron transport chain(ETC) complex I YP_001532340.1 putative inner membrane protein YP_001532341.1 Adenine deaminases reaction is important for adenine utilisation as a purine and also as a nitrogen source, Reaction: Adenine + H2O <=> hypoxanthine + NH3, Manganese dependent YP_001532342.1 found both in prokaryotes and eukaryotes; related to the human bile acid:sodium symporters; transmembrane proteins YP_001532343.1 esterification and transport of exogeneous long chain fatty acids, Reaction: ATP + a long-chain carboxylic acid + CoA <=> AMP + diphosphate + an acyl-CoA YP_001532344.1 NAD-binding, Reaction: 2-hydroxyglutarate + NAD+ <=> 2-oxoglutarate + NADH YP_001532345.1 PLP-dependent enzyme, Methionine metabolism, Reaction: O4-succinyl-L-homoserine + L-cysteine <=> L-cystathionine + succinate YP_001532346.1 This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides YP_001532347.1 contains middle and C-terminal domain, N-terminal domain not conserved YP_001532348.1 This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity YP_001532349.1 The MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients, similar to tetracycline resistence protein YP_001532350.1 Reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate YP_001532351.1 Substrate: acyl-carrier-protein (ACP), Reaction: Acyl-ACP + NAD+ = trans-2,3-dehydroacyl-ACP + NADH YP_001532352.1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids, Substrate: acyl-carrier-protein (ACP), Reaction: Acyl-ACP + malonyl-ACP <=> 3-oxoacyl-ACP + CO2 + ACP YP_001532353.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001532354.1 Fur family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes; Fur family YP_001532355.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001532356.1 Transfers the fatty acyl group on membrane lipoproteins YP_001532357.1 CBS domains have been shown to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet YP_001532359.1 PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation. YP_001532360.1 Fur family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes YP_001532361.1 putative inner membrane protein YP_001532362.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001532364.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001532365.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001532366.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001532367.1 involved in formation of nucleoid structure and affects gene expression, similar to Rba. capsulatus Puf and Puh operon regulator hvrA YP_001532368.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001532369.1 involved in septum formation YP_001532370.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001532371.1 conserved in Rhodobacteraceae YP_001532372.1 tryptophan biosynthesis, Reaction: N-(5-phospho-beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate YP_001532374.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001532375.1 structure: signal peptide, Poly-DDR-repeat domain YP_001532376.1 structure: signal peptide, Poly-DDR-repeat domain YP_001532377.1 C-terminal LuxR Helix-Turn-helix motif; LuxR family YP_001532378.1 TRAP gene cluster - dctPQM YP_001532379.1 TRAP gene cluster - dctPQM YP_001532380.1 TRAP gene cluster - dctPQM; DctM subunit YP_001532381.1 Glutamate racemase, which interconverts L-glutamate into D-glutamate, is required for the biosynthesis of peptidoglycan YP_001532382.1 Monooxygenases incorporate one hydroxyl group into substrates and are found in many metabolic pathways. In this reaction, two atoms of dioxygen are reduced to one hydroxyl group and one H2O molecule by the concomitant oxidation of NAD(P)H. YP_001532383.1 high similarity to predicted Carbon-monoxide dehydrogenase proteins YP_001532384.1 TRAP gene cluster - dctPQM; DctM subunit YP_001532385.1 TRAP gene cluster - dctPQM YP_001532386.1 TRAP gene cluster - dctPQM YP_001532387.1 N-terminal HTH region, C-terminal FCD effector binding domain; GntR family YP_001532389.1 contains Amidase signature (AS) motif, AS enzymes catalyse the hydrolysis of amide bonds (CO-NH2) YP_001532391.1 Enoyl-CoA hydratase and 3-2trans-enoyl-CoA isomerase are two enzymes involved in fatty acid metabolism YP_001532392.1 large family of oxidoreductases YP_001532394.1 This family includes 2-methylcitrate dehydratase (PrpD) that is required for propionate catabolism. It catalyses the third step of the 2-methylcitric acid cycle. YP_001532395.1 ABC transporter (importer) gene cluster: receptor YP_001532396.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532397.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532398.1 ABC transporter (importer) gene cluster (disrupted): ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532400.1 Family III CoA-transferases occur in prokaryotes and eukaryotes, and catalyse CoA-transfer reactions in a highly substrate- and stereo-specific manner YP_001532401.1 N-terminal, middle and C-terminal domain, Oxidoreductase acting on the CH-CH group of donors with other acceptors YP_001532405.1 high similarity to cobalt-zinc-cadmium resistance protein czcN, but no other czc genes in genome, inner membrane protein YP_001532407.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001532410.1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems, Reaction: 2 superoxide + 2 H+ = O2 + H2O2 YP_001532411.1 conserved in Rhodobacteraceae YP_001532412.1 This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export YP_001532416.1 contains B12-binding domain, enzymatic domain not present YP_001532417.1 catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine YP_001532419.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001532420.1 part of heterotrimer with purL(2500131741) and purQ(2500131101), required for enzymatic activity of the complex YP_001532421.1 Reaction: An alcohol + NAD+ = an aldehyde or ketone + NADH YP_001532422.1 Part of a heterotrimer with purL(2500131741) and purS(2500131099), Reaction: ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine + L-glutamate YP_001532423.1 integral membrane bound sensor histidine kinase, similar to C4-dicarboxylate transport sensor protein dctB YP_001532424.1 sigma54 specific, similar to C4-dicarboxylate transport transcriptional regulatory protein dctD; sigma54 specific, transcriptional regulator, Fis family YP_001532425.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001532426.1 two transmembrane domains, RDD domain YP_001532428.1 YbaK/prolyl-tRNA synthetase associated domain of unknown funktion YP_001532430.1 TRAP gene cluster - dctPQM; TAXI family YP_001532431.1 TRAP gene cluster - dctPQM; 4TM/12TM fusion protein YP_001532432.1 TRAP gene cluster - dctPQM YP_001532433.1 TRAP gene cluster - dctPQM YP_001532434.1 TRAP gene cluster - dctPQM; DctM subunit YP_001532435.1 Reaction: 1-Carboxyvinyl carboxyphosphonate <=> 3-(Hydrohydroxyphosphoryl)pyruvate + CO2 YP_001532437.1 Domains: GAF (present in phytochromes and cGMP-specific phosphodiesterases), FIS; Fis family YP_001532438.1 Reaction: An aldehyde + NAD+ + H2O = an acid + NADH YP_001532439.1 putative GDSL-like lipase; G-D-S-L YP_001532440.1 two YeeE/YedE-domains YP_001532441.1 inner membrane single-polypeptide secondary carrier YP_001532442.1 repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine. YP_001532443.1 Methylates ribosomal protein L11 YP_001532446.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001532447.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001532448.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001532449.1 conserved in Rhodobacteraceae YP_001532450.1 The significance of this thioesterase to the tol-pal system is unclear YP_001532451.1 outer membrane integrity and transport system Tol-Pal: TolQRAB-Pal YP_001532452.1 outer membrane integrity and transport system Tol-Pal: TolQRAB-Pal YP_001532453.1 outer membrane integrity and transport system Tol-Pal: TolQRAB-Pal YP_001532454.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001532455.1 outer membrane integrity and transport system Tol-Pal: TolQRAB-Pal YP_001532456.1 contains 1 Tetratricopeptide repeat YP_001532457.1 Ligates Lysine to a tRNA cytidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine YP_001532458.1 membrane-bound ATP-dependent protease universally conserved in prokaryotes YP_001532462.1 contains DEAD/H associated domain YP_001532466.1 contains 2 TPR domains, involved in protein-protein interaction YP_001532471.1 It can function as an adhesin and invasin, participate in biofilm formation, act as both an immune target and evasin, and serves as a receptor for several bacteriophages. YP_001532472.1 Bacterial type II and III secretion system protein YP_001532473.1 Domains: SAF YP_001532474.1 conserved in Rhodobacteraceae YP_001532475.1 conserved in Rhodobacteraceae YP_001532476.1 found in phages, type II, type III and type IV secretion systems YP_001532477.1 Reaction: Succinyl-CoA + a 3-oxo acid <=> succinate + a 3-oxoacyl-CoA YP_001532478.1 contains putative PAS photoreceptor domain YP_001532479.1 Reaction: Succinyl-CoA + a 3-oxo acid <=> succinate + a 3-oxoacyl-CoA YP_001532480.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001532481.1 required to protect incoming ssDNA from immediate degradation YP_001532482.1 Suppresses the inhibitory activity of the carbon storage regulator YP_001532483.1 part of oligomeric enzyme complex in the electron transport chain, transfers electrons from cytochrome c to the catalytic subunit I via hemA and copper YP_001532484.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001532486.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001532487.1 part of oligomeric enzyme complex in the electron transport chain, subunit I and III form the catalytic active compound YP_001532488.1 similar to SURF1 protein, involved in cox complex assembly YP_001532489.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001532490.1 uncharacterized zinc protease M16 family YP_001532491.1 protein N-Acetyl-transferase YP_001532492.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001532493.1 Reaction: 2 reduced ferredoxin + NADP+ <=> 2 oxidized ferredoxin + NADPH YP_001532494.1 conserved in bacteria YP_001532495.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001532496.1 catalyseses the six-electron reduction of sulphite to sulphide YP_001532497.1 conserved in Alphaproteobacteria YP_001532498.1 For siroheme; for sulfite reductase. YP_001532499.1 Helix-Turn-Helix motif, AsnC/Lrp subfamily; AsnC family YP_001532501.1 preference for inosine/uridine YP_001532503.1 contains 2 MazG domains YP_001532504.1 Degradation of proteins, peptides, and glycopeptides YP_001532505.1 RND transporters are involved in multidrug resistance, heavy metal resistance. The resistance is performed by H+ driven export of the toxic compounds. YP_001532506.1 RND transporters are involved in multidrug resistance and heavy metal resistance. The resistance is performed by H+ driven export of the toxic compounds.; RND family, MFP subunit YP_001532507.1 conserved in Rhodobacteraceae and Rhizobiales YP_001532508.1 contains PQQ repeat domain involved in PQQ binding YP_001532509.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001532510.1 Ste24p and the proteins related to it define a subfamily of proteins that are likely to function as intracellular, membrane-associated zinc metalloproteases YP_001532511.1 PLP-dependent enzyme YP_001532512.1 cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls, probably involved in cell-wall hydrolysis, septation or recycling YP_001532513.1 SAM dependent enzyme YP_001532514.1 penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively; 1A family YP_001532515.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001532516.1 proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine YP_001532517.1 putative inner membrane protein YP_001532519.1 catalytic activity has not been demonstrated YP_001532521.1 related to alkyl hydroperoxide reductase/ Thiol specific antioxidant YP_001532522.1 putative outer membrane protein YP_001532523.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001532524.1 Family M20 are Glutamate carboxypeptidases. Peptidase family M25 contains X-His dipeptidases YP_001532525.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_001532526.1 conserved in Rhodobacteraceae YP_001532527.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001532528.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001532529.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001532530.1 contains SurA domain and Peptidyl-prolyl cis-trans isomerase domain, periplasmatic YP_001532531.1 involved in outer membrane permeability YP_001532532.1 permease YjgP/YjgQ family of unknown function YP_001532533.1 permease YjgP/YjgQ family of unknown function YP_001532534.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001532535.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001532536.1 Cytochrome P450 enzymes are a superfamily of haem-containing mono-oxygenase YP_001532537.1 TRAP gene cluster - dctPQM; 4TM/12TM fusion protein YP_001532538.1 TRAP gene cluster - dctPQM; TAXI family YP_001532539.1 Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA.; Fis family YP_001532540.1 Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals. YP_001532542.1 Mg-dependent, Reaction: Myo-inositol phosphate + H2O = myo-inositol + phosphate YP_001532543.1 putative inner membrane serine protease YP_001532544.1 2 TPR, TPR mediates protein-protein interactions and the assembly of multiprotein complexes YP_001532545.1 contains DnaJ-Domain, wich mediats interaction with DnaK in heat shock proteins YP_001532546.1 In E. coli overexpression of this protein causes round morphology YP_001532547.1 conserved in Rhodobacteraceae YP_001532550.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001532552.1 integral membrane sensor and DNA-binding protein YP_001532553.1 Aerobic-type carbon monoxide dehydrogenase, middle subunit, part of heterotrimer coxLMS YP_001532554.1 Aerobic-type carbon monoxide dehydrogenase, small subunit, part of heterotrimer coxLMS, (2Fe-2S)-binding YP_001532555.1 Aerobic-type carbon monoxide dehydrogenase, large subunit, part of heterotrimer coxLMS YP_001532556.1 ATPase activity YP_001532557.1 Protein containing von Willebrand factor type A (vWA) domain YP_001532559.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001532560.1 putative acyl-coA synthetase YP_001532562.1 conserved in Rhodobacteraceae YP_001532564.1 Helix-Turn-Helix motif, XRE family, Domain of unknown funktion DUF955; XRE family YP_001532565.1 most enzymes of this family are NAD/NADP-dependent oxidoreductases YP_001532566.1 involved in the degradation of intracellular peptides generated by protein breakdown during normal growth or in response to nutrient starvation, Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). YP_001532568.1 Photolyase/Cryptochrome family protein, catalytic activity not proved YP_001532570.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001532572.1 gamma-glutamyl hydrolase activity YP_001532573.1 Catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine, PLP-dependent YP_001532574.1 domain weakly conserved YP_001532575.1 predicted domain weakly conserved YP_001532576.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001532577.1 transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane, heterodimer pntA/B; AB-specific YP_001532578.1 Reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate YP_001532579.1 dimethyl sulphoxide reductase is a heterotrimeric enzyme, composed of a membrane extrinsic catalytic dimer (DmsAB) and a membrane intrinsic polytopic anchor subunit (DmsC) YP_001532580.1 dimethyl sulphoxide reductase is a heterotrimeric enzyme, composed of a membrane extrinsic catalytic dimer (DmsAB) and a membrane intrinsic polytopic anchor subunit (DmsC), 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_001532581.1 dimethyl sulphoxide reductase is a heterotrimeric enzyme, composed of a membrane extrinsic catalytic dimer (DmsAB) and a membrane intrinsic polytopic anchor subunit (DmsC), molybdopterin oxidoreductase Fe4S4 region YP_001532582.1 Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides, homotrimer YP_001532583.1 domain found in various proteins YP_001532584.1 Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001532585.1 catalyses the second step in D-galactonate degradation YP_001532586.1 large family of oxidoreductases, NAD, NADP-dependent YP_001532587.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001532588.1 glycoside hydrolase family 4 protein, Hydrolysis of terminal, non-reducing alpha-D-galactose residues, NAD and Mn-dependent YP_001532589.1 ABC-type sugar transport system, permease component, no ATPase in cluster YP_001532590.1 ABC-type sugar transport system, permease component, no ATPase in cluster YP_001532591.1 ABC-type sugar transport system, ligand binding component, no ATPase in cluster YP_001532592.1 Helix-Turn-Helix motif, iclR subfamily; IclR family YP_001532593.1 ABC transporter (importer) gene cluster (disrupted): ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532596.1 putative protein-phosphotyrosine-phosphatase activity, ArsR family regulators are sensitive to metal ions; ArsR family YP_001532597.1 tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis; type I YP_001532598.1 The MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients YP_001532599.1 the exo genes are involved in exopolysaccharide biosynthesis, exoD of Rhizobium meliloti encodes a function needed for alfalfa nodule invasion YP_001532601.1 most enzymes of this family are NAD/NADP-dependent oxidoreductases YP_001532603.1 contains winged helix DNA-binding motif; MerR family YP_001532604.1 sodium-dependent uptake of extracellular glutamate YP_001532605.1 RND transporters are involved in multidrug resistance, heavy metal resistance. The resistance is performed by H+ driven export of the toxic compounds. YP_001532606.1 RND transporters are involved in multidrug resistance and heavy metal resistance. The resistance is performed by H+ driven export of the toxic compounds.; RND family, MFP subunit YP_001532607.1 two membrane helix type ion channel YP_001532608.1 carbohydrate degradation YP_001532609.1 zinc-dependent, homodimeric enzyme YP_001532611.1 putative enzyme involved in myo-inositol catabolism YP_001532612.1 putative enzyme involved in myo-inositol catabolism, Thiamine-dependent YP_001532613.1 NAD-dependent oxidoreductase YP_001532614.1 putative enzyme involved in myo-inositol catabolism YP_001532615.1 NAD-dependent oxidoreductase YP_001532616.1 Helix-Turn-Helix motif, Sugar -binding domain; LacI family YP_001532617.1 ATPase gene cluster: periplasmatic binding component, permease component, ATPase component YP_001532618.1 ATPase gene cluster: periplasmatic binding component, permease component, ATPase component YP_001532619.1 ATPase gene cluster: periplasmatic binding component, permease component, ATPase component YP_001532623.1 domain is found in amino transferases, and other enzymes including cysteine desulphurase, PLP dependent enzyme YP_001532624.1 high similarity to Respiratory-chain NADH dehydrogenase domain 24 kDa and 51 kDa subunits(PMID:2187144) YP_001532625.1 complex with fdhB, Molybdopterin oxidoreductase, contains Fe-S clusters YP_001532626.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001532628.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001532632.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_001532633.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001532636.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001532637.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001532638.1 Specifically catalyzes the dephosphorylation of 2-phosphoglycolate; subfamily IA, variant 3 YP_001532640.1 FAD-dependent, Reaction: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor YP_001532643.1 involved in leucine catabolism YP_001532644.1 involved in leucine catabolism YP_001532646.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_001532647.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001532650.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532651.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001532652.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532654.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532656.1 catalyzes the transfer of electrons from NADH to ubiquinone YP_001532658.1 conserved in Rhodobacteraceae YP_001532659.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001532663.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532664.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532665.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532667.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532669.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532670.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001532671.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532672.1 Catalyzes the transfer of electrons from NADH to quinone YP_001532674.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001532677.1 TPR containing proteins are involved in assambly of multiprotein complexes YP_001532679.1 Increases the formation of ribosomal termination complexes and stimulates activities of prfA and prfB, GTP binding YP_001532681.1 contains 2 UspA domains, expression is enhanced when the cell is exposed to stress agents, enhances the rate of cell survival during prolonged exposure to such conditions YP_001532682.1 most enzymes of this family are NAD/NADP-dependent oxidoreductases YP_001532683.1 the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient YP_001532684.1 unknown specificity, high similarity to iron ABC transporters YP_001532685.1 Helix-turn-helix type 11 domain protein YP_001532686.1 Sec-independent translocation protein mttA/Hcf106, Members of this protein family are involved in a sec independent translocation mechanism. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export. YP_001532687.1 Sec-independent protein secretion pathway components; TatB subunit YP_001532688.1 Sec-independent protein secretion pathway components; TatC subunit YP_001532691.1 Integral membrane protein family that includes the antibiotic resistance protein MarC. These proteins may be transporters. YP_001532692.1 duplicated ATPase domain YP_001532693.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001532695.1 no evidence for predicted domain YP_001532696.1 ABC transporter (importer) gene cluster: receptor YP_001532697.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532698.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532700.1 ABC transporter (importer) gene cluster: ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532701.1 most enzymes of this family are NAD/NADP-dependent oxidoreductases YP_001532703.1 SnoaL-like polyketide cyclase family protein YP_001532704.1 Catalyzes the stereospecific oxidation of D-lactate to pyruvate; cytochrome YP_001532705.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001532706.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001532708.1 Helix-Turn-Helix motif; TetR family YP_001532709.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001532710.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001532712.1 This family includes class II aldolases and adducins which have not been ascribed any enzymatic function. YP_001532713.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001532714.1 ABC transporter (importer) gene cluster (disrupted): ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532715.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532716.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532717.1 ABC transporter (importer) gene cluster: receptor YP_001532719.1 catalyses the hydrolysis of creatinine to creatine YP_001532720.1 This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily YP_001532721.1 catalyseses the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species YP_001532722.1 catalyseses the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species YP_001532723.1 This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. YP_001532724.1 Amidohydrolases are a diverse superfamily of enzymes which catalyse the hydrolysis of amide or amine bonds in a large number of different substrates including urea, cytosine, AMP, formylmethanofuran YP_001532725.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532726.1 ABC transporter (importer) gene cluster: ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532727.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532728.1 Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA YP_001532730.1 binds and unfolds substrates as part of the ClpXP protease YP_001532731.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001532733.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis YP_001532734.1 Mammalian cell entry related domain YP_001532737.1 transfers a Leu or Phe to the amino end of certain proteins to enable degradation. The N-terminal residue controls the biological half-life of many proteins via the N-end rule pathway. YP_001532738.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001532739.1 This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.; biotin carboxyl carrier protein YP_001532740.1 contains several Hemolysin-type calcium-binding repeats found in proteins that are secreted into the growth medium by a mechanism that does not require a cleaved N-terminal signal sequence YP_001532741.1 domain structure is similar to that of dehydrogenases, amidohydrolases, and oxidoreductases, however sequence and structural analyses have shown that it does not belong to the dehydrogenase or the amidohydrolase superfamilies of proteins YP_001532742.1 Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates cheY, the response regulator involved in flagellar movement and chemotaxis. YP_001532743.1 ABC transporter (importer) gene cluster: 2nd ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532744.1 ABC transporter (importer) gene cluster: 1st ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532745.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532746.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532747.1 ABC transporter (importer) gene cluster: receptor; periplasmic binding protein, putative YP_001532748.1 Helix-Turn-Helix motif; XRE family YP_001532749.1 DNA-binding motif, normally found at the C-terminus, is missing YP_001532751.1 Signal transducing histidine kinases are the key elements in two-component signal transduction systems, which control complex processes such as the initiation of development in microorganisms YP_001532754.1 TraR/DksA family YP_001532756.1 ABC transporter (importer) gene cluster: receptor YP_001532757.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532758.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532759.1 ABC transporter (importer) gene cluster: ATP binding cassette (ABC) domain; part of a heterotetramer YP_001532761.1 conserved in Rhodobacteraceae YP_001532763.1 conserved in Rhodobacteraceae YP_001532764.1 ABC transporter (importer) gene cluster: receptor; substrate-binding protein YP_001532765.1 ABC transporter (importer) gene cluster: fused ATP binding cassette (ABC) domains; part of a heterotrimer YP_001532766.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotrimer YP_001532767.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotrimer YP_001532768.1 This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor (PFAM, INTERPRO; COG: NAD-dependent enzyme). YP_001532769.1 Fumarase, or fumarate hydratase, is a component of the citric acid cycle.; Fe-S type, tartrate/fumarate subfamily, alpha subunit YP_001532770.1 represents a citrate:acetyl-ACP transferase, alpha subunit of the holoenzyme citrate lyase composed of alpha, beta, and acyl carrier protein subunits in a stoichiometric relationship of 6:6:6TCA-cycle YP_001532771.1 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine YP_001532772.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001532773.1 This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. YP_001532774.1 contains substrate binding domain, putative homotetramer; LysR family YP_001532775.1 These CoA-transferases occur in prokaryotes and eukaryotes, and catalyse CoA-transfer reactions in a highly substrate- and stereo-specific manner, Members: formyl-CoA:oxalate CoA-transferase, succinyl-CoA:(R)-benzylsuccinate CoA-transferase, (E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase, butyrobetainyl-CoA:(R)-carnitine CoA-transferase YP_001532777.1 remnant of Xaa-Pro dipeptidase YP_001532778.1 domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function YP_001532779.1 ABC transporter gene cluster, permease component YP_001532780.1 ABC transporter gene cluster, ATPase component; ATPase subunit YP_001532781.1 ABC transporter gene cluster, periplasmatic substrate binding component YP_001532782.1 catalyzes the formation of pyruvate from D-cysteine YP_001532783.1 contains substrate binding domain, putative homotetramer; LysR family YP_001532784.1 C-Terminus conserved YP_001532786.1 TRAP gene cluster - dctPQM; TAXI family YP_001532787.1 TRAP gene cluster - dctPQM; 4TM/12TM fusion protein YP_001532788.1 contains 1 UspA domain, expression is enhanced when the cell is exposed to stress agents, enhances the rate of cell survival during prolonged exposure to such conditions YP_001532789.1 PLP-dependent enzyme YP_001532792.1 TonB protein interacts with outer membrane receptor proteins that carry out high-affinity binding and energy-dependent uptake of specific substrates into the periplasmic space YP_001532793.1 NnrS is a putative heme-Cu protein (NnrS) and a member of the short-chain dehydrogenase family. YP_001532794.1 Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system YP_001532795.1 Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import. YP_001532796.1 Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import. YP_001532799.1 Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. YP_001532800.1 protects the organism against invading foreign DNA, part of a heteromeric enzyme complex, mod (modification methyltransferase)subunit is missing YP_001532801.1 phage integrase family YP_001532802.1 outer membrane protein YP_001532803.1 fusion of ribosomal protein L21 and COG3743 YP_001532804.1 involved in the peptidyltransferase reaction during translation YP_001532809.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001532810.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001532812.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001532815.1 similar to ornithine acyl[acyl carrier protein] N-acyltransferase in S. pomeroyi YP_001532816.1 Glycerophospholipid metabolism YP_001532817.1 similar to Glutamyl-Q tRNA(Asp) synthetase which catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). YP_001532818.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001532819.1 negatively supercoils closed circular double-stranded DNA YP_001532820.1 not in the trp operon, Usg is normally found in trpF, trpB, and trpA context YP_001532821.1 The DsbB protein oxidises the periplasmic protein DsbA which in turn oxidises cysteines in other periplasmic proteins in order to make disulfide bonds YP_001532822.1 the exo genes are involved in exopolysaccharide biosynthesis, exoD of Rhizobium meliloti encodes a function needed for alfalfa nodule invasion YP_001532823.1 TRAP gene cluster - dctPQM YP_001532824.1 TRAP gene cluster - dctPQM YP_001532825.1 TRAP gene cluster - dctPQM; DctM subunit YP_001532828.1 DOMAINS: FAD dependent oxidoreductase, Glycine cleavage T-protein, involved in amine and polyamine degradation YP_001532829.1 Betaine / Carnitine / Choline Transporter, The BCCT proteins contain 12 transmembrane regions and are energized by proton symport YP_001532830.1 ABC transporter (importer) gene cluster: 2 fused ATPase/ Oligopeptide/dipeptide transporter, C-terminal region domains; ATPase subunit YP_001532831.1 ABC transporter (importer) gene cluster: 2nd membrane spanning domain (MSD); part of a heterotetramer YP_001532832.1 ABC transporter (importer) gene cluster: 1st membrane spanning domain (MSD); part of a heterotetramer YP_001532833.1 ABC transporter (importer) gene cluster: receptor YP_001532834.1 only 1 DNA-binding domain, no substrate binding domain; AraC family YP_001532835.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001532836.1 Catalyzes the phosphorylation of UMP to UDP YP_001532837.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001532838.1 Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide YP_001532839.1 catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate (PA): CDP-diacylglycerol is an important branch point intermediate in both prokaryotic and eukaryotic organisms. YP_001532840.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001532841.1 Zinc-Metalloprotease; Degrades both heat shock sigma factors rpoE and rpoH. YP_001532842.1 involved in the assembly of proteins into the outer membrane of Gram-negative bacteria YP_001532843.1 Skp (OmpH) has been characterised as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery YP_001532844.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001532845.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001532846.1 COG: COG3494 - Uncharacterized protein conserved in bacteria, PFAM: pfam06230 Protein of unknown function (DUF1009) YP_001532847.1 TIGRFAM: TIGR00215 lipid-A-disaccharide synthase, COG: COG0763 - Lipid A disaccharide synthetase, PFAM: LpxB, pfam02684 Lipid-A-disaccharide synthetase, KEGG Pathway: Lipopolysaccharide biosynthesis YP_001532848.1 SUPERFAMILY: SSF51294 YP_001532849.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001532850.1 PFAM: PF06627; related to DUF1153 YP_001532851.1 SWISSPROT Q45994: Cell cycle transcriptional regulator; PRODOM: PD000039, PD000329; PFAM: PF00486, PF00072; SMART: SM00448, PROFILE: PS50110; SUPERFAMILY: SSF52172, COG: COG0745 - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Response regulator sokA YP_001532852.1 SWISSPROT P15042: DNA ligase; PFAM: pfam01653, pfam03120, pfam00533, pfam03119; COG: COG0272 - NAD-dependent DNA ligase (contains BRCT domain type II), TIGRFAM: TIGR00575 DNA ligase, NAD-dependent; NAD-dependent YP_001532853.1 catalyzes branch migration in Holliday junction intermediates YP_001532854.1 SWISSPROT P42663: Thermostable carboxypeptidase 1; PFAM: pfam02074; COG: COG2317 - Zn-dependent carboxypeptidase YP_001532855.1 PFAM: pfam02628; COG: COG1612 - Uncharacterized protein required for cytochrome oxidase assembly YP_001532856.1 PFAM: pfam00588; COG: COG0565 - rRNA methylase; TIGRFAM: TIGR00050 rRNA methylase, putative, group 1; SpoU family YP_001532857.1 PFAM: pfam02581; COG: COG0352 Thiamine monophosphate synthase; TIGRFAM: TIGR00693 thiamine-phosphate pyrophosphorylase YP_001532858.1 SWISSPROT Q53158: Phosphoribosyl-AMP cyclohydrolase; PFAM: pfam01502, COG: COG0139 - Phosphoribosyl-AMP cyclohydrolase YP_001532859.1 PFAM: PF01592, COG: COG0822 - NifU homolog involved in Fe-S cluster formation.; related to NIFU YP_001532860.1 PFAM: pfam02653, COG: COG4177- ABC-type branched-chain amino acid transport system / permease component; related to amino acid / sugar transport system YP_001532861.1 PFAM: pfam02653, COG: COG0559- Branched-chain amino acid ABC-type transport system, permease components; similar to branched -chain amino acid transporter, permease subunit YP_001532862.1 associated with ABC-transport system cluster YP_001532863.1 SWISSPROT P22731: High-affinity branched-chain amino acid transport ATP-binding protein livF; PFAM: PF00005; PROSITE: PS50893; SMART: SM00382; COG: COG0410 -ABC-type branched-chain amino acid transport systems, ATPase component. YP_001532864.1 SWISSPROT P0A9S7: High-affinity branched-chain amino acid transport ATP-binding protein livG; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382; COG: COG0411 - ABC-type branched-chain amino acid transport systems, ATPase component; livG YP_001532865.1 PFAM: pfam01094, COG: COG0683 - ABC-type branched-chain amino acid transport systems, periplasmic component, SWISSPROT: P04816: Leucine-specific-binding protein livK [Precursor]; SUPERFAMILY: SSF53822; associated with ABC transport system; LivK YP_001532866.1 COG: COG2133, PFAM (GSDH): pfam07995, Gene3D: G3DSA:2.120.10.30, SUPERFAMILY: SSF50952, SWISSPROT P75804: Soluble aldose sugar dehydrogenase yliI [Precursor] YP_001532868.1 PFAM: PF01965, PF00165; COG: COG4977 - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; AraC family YP_001532869.1 SWISSPROT P80574: Phospho-2-dehydro-3-deoxyheptonate aldolase aroH; PFAM: PF01474-Class-II DAHP synthetase family, COG: COG3200 - 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, TIGRFAM: TIGR01358 3-deoxy-7-phosphoheptulonate synthase, class II YP_001532870.1 pfam07310, COG5388 YP_001532871.1 PFAM: pfam03755, pfam08340; COG: COG1561 Uncharacterized stress-induced protein; TIGRFAM: TIGR00255 conserved hypothetical protein; similar to YicC-like YP_001532872.1 Essential for recycling GMP and indirectly, cGMP YP_001532873.1 PFAM: PF00132, COG: COG0663 COG: Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; SUPERFAMILY: SSF51161, SWISSPROT: P0A9W9 Protein yrdA; LpxA-like YP_001532875.1 SWISSPROT P08400: Phosphate regulon sensor protein phoR; PFAM: PF02518, PF00512; SMART: SM00387, SM00091; SM00388; COG: COG5002-Signal transduction histidine kinase; putative phosphate regulon sensor protein (phoR) YP_001532876.1 SWISSPROT Q4L694: Phosphate-binding protein pstS [precursor]; COG: COG0226 - ABC-type phosphate transport system, periplasmic component; Gene3D: G3DSA:3.40.190.10; SUPERFAMILY: SSF53850; associated with ABC transport system involved in phosphate import YP_001532877.1 SWISSPROT: P0AGH8 Phosphate transport system permease protein pstC, TIGRFAM: TIGR02138, PFAM: PF00528, COG: COG0573, PROSITE: PS50928 YP_001532878.1 SWISSPROT P07654: Phosphate transport system permease protein pstCTIGRFAM: TIGR00974 - phosphate ABC transporter, permease protein PstA, PFAM: pfam00528, COG: COG0573 - ABC-type phosphate transport system, permease component; PROSITE: PS50928 YP_001532879.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001532880.1 SWISSPROT: P0A9K7, TIGRFAM: TIGR02135, PFAM: pfam01895 YP_001532881.1 SWISSPROT: P0AFJ5 Phosphate regulon transcriptional regulatory protein, TIGRFAM: TIGR02154 phosphate regulon transcriptional regulatory protein PhoB, PFAM: PF00072, PF00486, COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; SUPERFAMILY: SSF52172; CheY-like YP_001532882.1 SWISSPROT: P45394 Inner membrane protein yrbG, PFAM: PF01699, TIGRFAM: TIGR00367 K+-dependent Na+/Ca+ exchanger related-protein, COG: COG0530 - Ca2+/Na+ antiporter; PANTHER: PTHR10846; sodium/potassium/calcium exchanger family YP_001532883.1 COG: COG0265, SUPERFAMILY: SSF50494, PFAM: PF00595, PF00089; peptidase S1B family; precursor YP_001532884.1 PFAM: PF07969, SUPERFAMILY: SSF51556; COG: COG1574 - Predicted metal-dependent hydrolase with the TIM-barrel fold YP_001532886.1 PFAM: PF01734, SUPERFAMILY: SSF52151; COG: COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; similar to Patatin-like phospholipase YP_001532887.1 SWISSPROT P99093: 3-oxoacyl-[acyl-carrier-protein] reductase fabG; TIGRFAM: TIGR01963 3-hydroxybutyrate dehydrogenase; PRINTS: PR00080, PR00081; PANTHER: PTHR19410, PFAM: PF00106 short chain dehydrogenase/reductase, SUPERFAMILY: SSF51735, Gene3D: G3DSA:3.40.50.720, COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_001532888.1 COG: COG4166 - ABC-type oligopeptide transport system, periplasmic component; PFAM: PF00496 YP_001532889.1 PFAM: PF04367; COG: COG2928 - Uncharacterized conserved protein YP_001532890.1 SUPERFAMILY: SSF53613 Ribokinase-like; COG: COG0524, Sugar kinase, ribokinase family; PFAM: PF00294; ribokinase family YP_001532891.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001532892.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001532893.1 PFAM: PF00196, PF03472; PROSITE: PS50043; SUPERFAMILY: SSF75516, SSF46894; COG: COG2197; luxR family YP_001532894.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001532895.1 SWISSPROT: P44093, PFAM: PF07005; similar to uncharacterized protein HI1011 YP_001532896.1 SUPERFAMILY: SSF53639; PFAM: PF00596; COG: COG0235, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases YP_001532897.1 PFAM: PF01261, Gene3D: G3DSA:3.20.20.150, SUPERFAMILY: SSF51658, SWISSPROT: Q6NUD4, P30147; COG: COG3622 YP_001532898.1 PFAM: PF01381, PF07883; SUPERFAMILY: SSF51182; Gene3D: G3DSA:1.10.260.40; HTH type YP_001532899.1 COG: COG0318, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; PFAM: PF00501, PANTHER: PTHR11968, PROSITE: PS00455, Gene3D: G3DSA:3.40.50.980, G3DSA:3.30.300.30 YP_001532900.1 PFAM: PF01323, SUPERFAMILY: SSF52833, COG: COG2761, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis YP_001532902.1 SWISSPROT: P28246, TIGRFAM: TIGR00710- Drug resistance transporter Bcr/CflA subfamily, PANTHER: PTHR10074 Major facilitator subfamily member, Bicyclomycin resistance protein; COG: COG2814- Arabinose efflux permease; PFAM: PF07690; SUPERFAMILY: SSF103473; PROSITE: PS50850; putative bicyclomycin resistance protein YP_001532904.1 SWISSPROT P30958: Transcription-repair-coupling factor, TIGRFAM: TIGR00580 -Transcription-repair coupling factor; PFAM: PF03461, PF02559, PF00270, PF00271 YP_001532906.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001532907.1 PROSITE: PS51257, PFAM: pfam04366, COG: COG2930 - Uncharacterized conserved protein YP_001532908.1 PFAM: PF01804, COG: COG2366 - Protein related to penicillin acylase; putative penicillin acylase YP_001532909.1 SWISSPROT: P25519 - GTP-binding protein hflX, PANTHER: PTHR10229, PFAM: PF01926, SUPERFAMILY: SSF52540, Gene3D: G3DSA:3.40.50.300 YP_001532910.1 Stimulates the elongation of poly(A) tails YP_001532911.1 SWISSPROT: Q9L6L2, P23849 - Trk system potassium uptake protein trkH; COG: COG0168 - Trk-type K+ transport systems, membrane components; PFAM: PF02386 YP_001532912.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001532915.1 SWISSPROT: P03029 - Nitrogen assimilation regulatory protein ntrX; PFAM: PF00072, PF00158, PF02954; SUPERFAMILY: SSF52172, SSF52540; COG: COG2204; sigma factor 54 YP_001532916.1 SWISSPROT Q04850: Nitrogen regulation protein ntrY; PANTHER: Two-component Histidine Kinase; COG: COG5000 & PIRSF - Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; PFAM: PF00512, PF00672, PF02518; TIGRFAM: TIGR00229; SMART: SM00091; PROSITE: PS50112; nitrogen regulation protein YP_001532917.1 SWISSPROT P10577: Nitrogen assimilation regulatory protein; COG: COG2204 - Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: PF02954, PF00072, PF00158; SUPERFAMILY: SSF52172; sigma factor 54 YP_001532918.1 SWISSPROT P09431, P0AFB5: Nitrogen regulation protein ntrB; COG: COG3852 - Signal transduction histidine kinase, nitrogen specific; PFAM: PF00512, PF02518; SMART: SM00091 YP_001532919.1 TIGRFAM: Dihydrouridine synthase TIM-barrel, NifR3; COG: COG0042 - tRNA-dihydrouridine synthase, PFAM: pfam01207; alternative gene name: nifR YP_001532920.1 SWISSPROT Q5LRN5: Bifunctional enzyme ispD/ispF; TIGRFAM: TIGR00151, TIGR00453; PFAM: pfam01128, pfam02542 YP_001532921.1 SWISSPROT: P18200; COG: COG1267 - Phosphatidylglycerophosphatase A and related proteins; PFAM: PF04608 YP_001532922.1 TIGRFAM: TIGR00199 competence/damage-inducible protein CinA C-terminal domain; COG: COG1546 - Uncharacterized protein (competence- and mitomycin-induced); PFAM: pfam02464 YP_001532923.1 COG: COG2867-Oligoketide cyclase/lipid transport protein; PFAM: PF03364 YP_001532924.1 SWISSPROT P0A9M2: Hypoxanthine phosphoribosyltransferase, also high similarity to hypoxanthine-guanine phosphoribosyltransferase (SWISSPROT P37171); COG: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; PFAM: PF00156 YP_001532925.1 similar to transmembrane transport protein YP_001532926.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001532929.1 SWISSPROT O93658: Trimethylamine methyltransferase mttB; COG: COG5598 - Trimethylamine:corrinoid methyltransferase; PFAM: pfam06253 YP_001532930.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001532931.1 COG: COG1434-Uncharacterized conserved protein; PFAM: pfam02698- Uncharacterized ACR, COG1434 YP_001532932.1 SWISSPROT Q68XV0: S-adenosylmethionine uptake transporter; PFAM: pfam00892; similar to S-adenosylmethionine uptake transporter YP_001532933.1 SUPERFAMILY; SST56935-Porins; PFAM: PF03349-Outer membrane protein transport protein (OMPP1/FadL/TodX); COG: COG2067-Long-chain fatty acid transport protein YP_001532934.1 PFAM: PF00892, SUPERFAMILY: SSF103481; similar to Multidrug resistance efflux transporter EmrE YP_001532935.1 SUPERFAMILY: SSF52540 YP_001532936.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001532937.1 COG: COG0596- Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); PFAM: pfam00561; SPRINTS: PR00111 YP_001532938.1 PFAM: PF03976 YP_001532939.1 PFAM: PF00440; COG: COG1309-Transcriptional regulator; similar to HTH-type transcriptional regulator (tetR family) YP_001532940.1 SWISSPROT P69874: Spermidine/putrescine import ATP-binding protein potA; COG: COG3842-ABC-type spermidine/putrescine transport systems, ATPase components; TIGRFAM: TIGR01187- spermidine/putrescine ABC transporter ATP-binding subunit; PFAM: PF00005, PF08402; SMART: SM00382; PANTHER: PTHR19222 YP_001532941.1 SWISSPROT P0AFR9: Inner membrane ABC transporter permease protein ydcV, P0AFK6: Spermidine/putrescine transport system permease protein potC; COG: COG1177-ABC-type spermidine/putrescine transport system, permease component II; PFAM: PF00528; PROSITE: PS50928; associated with spermidine/putrescine transport system YP_001532942.1 SWISSPROT P0AFK4: Spermidine/putrescine transport system permease protein potB; COG: COG1176-ABC-type spermidine/putrescine transport system, permease component I; PFAM: pfam00528; PROSITE: PS50928 YP_001532943.1 COG: COG2329-Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides; PFAM: pfam03992; SUPERFAMILY: SSF54909 YP_001532944.1 forms a direct contact with the tRNA during translation YP_001532945.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001532946.1 TIGRFAM: TIGR00369-Phenylacetic acid degradation-related protein; COG: COG2050-Uncharacterized protein, possibly involved in aromatic compounds catabolism; PFAM: PF03061; SWISSPROT Q9I644: UPF0152 protein PA0474, P76084: Phenylacetic acid degradation protein paaI; similar to Phenylacetic acid degradation protein paaI YP_001532947.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001532948.1 COG: COG0741-Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); PFAM: PF01464 YP_001532949.1 TIGRFAM: TIGR00621; COG: COG0629; PFAM: pfam00436; PANTHER: PTHR10302; PROSITE: PS50935; SWISSPROT P0AGE0 YP_001532951.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001532952.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001532954.1 SWISSPROT: P0A8P8 Tyrosine recombinase xerD; COG: COG4974 - Site-specific recombinase XerD; PFAM: pfam00589, pfam02899; SUPERFAMILY: SSF47823, SSF56349 YP_001532955.1 COG: COG0622 - Predicted phosphoesterase; SUPERFAMILY: Metallo-dependent phosphatases; Gene3D: [PDB] Hydrolase YP_001532956.1 SWISSPROT P37908: UPF0053 inner membrane protein yfjD; PFAM: pfam01595, pfam03471, pfam00571; PANTHER: PTHR22777 YP_001532957.1 SWISSPROT P39342: Uncharacterized protein yjgR; PFAM: pfam05872; SUPERFAMILY: SSF52540; Gene3D: G3DSA:3.40.50.300; similar to uncharacterized protein yjgR (E.coli) YP_001532958.1 COG: COG5342 - Invasion protein B, involved in pathogenesis, PFAM: pfam06776; similar to Invasion protein B YP_001532959.1 PANTHER: Polyketide synthase-related; COG: COG0304 - 3-oxoacyl-(acyl-carrier-protein) synthase; SWISSPROT P04684: Nodulation protein E, P0AAI5: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: pfam02801, pfam00109; PROSITE: PS00606 YP_001532960.1 SWISSPROT P0A6A8: Acyl carrier protein; TIGRFAM: TIGR00517; PFAM: PF00550; PROSITE: PS50075, PS00012; phosphopantetheine attachment site YP_001532961.1 COG: COG1044 - UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; TIGRFAM: TIGR01853; PFAM: pfam04613, PF00132 YP_001532962.1 COG: COG2989 - Uncharacterized protein conserved in bacteria; PFAM: pfam01471; SWISSPROT P22525:Uncharacterized protein ycbB; related to uncharacterized protein ycbB (E.coli) YP_001532963.1 COG: COG3108 - Uncharacterized protein conserved in bacteria; PFAM: pfam05951; SWISSPROT P0AB06: Uncharacterized protein ycbK; similar to uncharcaterized protein ycbK YP_001532964.1 SWISSPROT: 6-phosphofructokinase isozyme 2 (Phosphofructokinase-2) [pfkB]; PROSITE: PS00583; PFAM: PF00294; SUPERFAMILY: SSF53613 YP_001532965.1 SWISSPROT Q99289: Thermolabile hemolysin [Precursor]; PFAM: PF00353; PROSITE: PS00330; SPRINT: PR00313 ; SUPERFAMILY: SSF51120; Gene3D: G3DSA:2.150.10.10; COG: COG2931; Calcium binding YP_001532966.1 SWISSPROT P77444: Cysteine desulfurase. Synonym: Selenocysteine lyase; TIGRFAM: TIGR01979; COG: COG0520 - Selenocysteine lyase; PFAM: PF00266; PROSITE: PS00595; SUPERFAMILY: SSF53383 YP_001532967.1 associated with suf system YP_001532968.1 associated with suf sytem YP_001532969.1 SWISSPROT P77689: Protein sufD; COG: COG0719 - ABC-type transport system involved in Fe-S cluster assembly, permease component; PFAM: pfam01458; SUPERFAMILY SSF101960: Stabilizer of iron transporter SufD YP_001532970.1 SWISSPROT P77499: Probable ATP-dependent transporter sufC; TIGRFAM: TIGR01978 FeS assembly ATPase SufC; PANTHER: PTHR19222:SF6-ABC TRANSPORTER; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001532971.1 PFAM: PF01906; COG: COG0393 - Uncharacterized conserved protein YP_001532974.1 with SufCD activates cysteine desulfurase SufS YP_001532975.1 SWISSPROT P05341: Cysteine desulfurase; COG: COG1104 - Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; PANTHER: Cysteine desulforase; PFAM: PF00266; Gene3D: G3DSA:3.40.640.10; alternative gene name: iscS YP_001532976.1 SWISSPROT P0AGK8: HTH-type transcriptional regulator iscR; TIGRFAM: TIGR00738 rrf2 family protein (putative transcriptional regulator); COG: COG1959 - Predicted transcriptional regulator; PFAM: PF02082; PROSITE: PS51197; SUPERFAMILY: SSF46785 YP_001532977.1 COG: COG2945 - Predicted hydrolase of the alpha/beta superfamily; PFAM: pfam00561; SUPERFAMILY: SSF53474 YP_001532979.1 PFAM: pfam01988; COG: COG1814 - Uncharacterized membrane protein YP_001532980.1 PFAM: PF02588; COG: COG1284 - Uncharacterized conserved protein YP_001532981.1 SUPERFAMILY: Multidrug resistance efflux transporter EmrE; SWISSPROT P23895: Multidrug transporter emrE; PFAM: PF00893; SUPERFAMILY: SSF103481 YP_001532983.1 PROSITE: PS51257 YP_001532984.1 PFAM: PF07045 YP_001532985.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001532986.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001532987.1 COG: COG4191 - Signal transduction histidine kinase regulating C4-dicarboxylate transport system; SMART: SM0009, SM00448, SM00387, SM00388; PROSITE: PS50110, PS50109; PFAM: PF00072, PF02518, PF00512; SPRINTS: PR00344; SUPERFAMILY: SSF55874 YP_001532988.1 SWISSPROT P36929: Ribosomal RNA small subunit methyltransferas B / rRNA (cytosine-C(5)-)-methyltransferase; PFAM: PF01189; SUPERFAMILY: SSF53335 YP_001532989.1 TIGRFAM: TIGR01302 inosine-5-monophosphate dehydrogenase; COG: COG0516 - IMP dehydrogenase/GMP reductase; PANTHER: INOSINE-5-MONOPHOSPHATE DEHYDROGENASE (PTHR11911:SF6); PFAM: PF00478, PF00571; SMART: SM00116 YP_001532990.1 SWISSPROT Q47098: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: PF03328; Gene3D: G3DSA:3.20.20.60; SUPERFAMILY: SSF51621 YP_001532991.1 SWISSPROT P68187: Maltose/maltodextrin import ATP-binding protein malK; COG: COG3839 - ABC-type sugar transport systems, ATPase components; PFAM: PF00005, PF08402; SMART: SM00382; SUPERFAMILY: SSF50331 YP_001532992.1 SWISSPROT Q9Z3R8: Probable alpha-glucosidase; COG: COG0366 - Glycosidases; PFAM: PF00128; SMART: SM00642; SUPERFAMILY: SSF51011, SSF51445 YP_001532993.1 SWISSPROT Q9Z3R7: Alpha-glucoside transport system permease protein aglG, P77716: Inner membrane ABC transporter permease protein ycjP; PFAM: PF00528; PROSITE: PS50928; associated with alpha-glucoside transport system YP_001532994.1 SWISSPROT P0AFR7: Inner membrane ABC transporter permease protein ycjO, Q9Z3R6: Alpha-glucoside transport system permease protein aglF; PFAM: PF00528; PROSITE: PS50928; associated with alpha-glucoside transport system YP_001532995.1 SWISSPROT Q9Z3R5: Alpha-glucosides-binding periplasmic protein aglE [Precursor]; COG: COG1653 - ABC-type sugar transport system, periplasmic component; PFAM: PF01547; associated with alpha-glucoside transport system YP_001532996.1 SWISSPROT Q9Z3R4: HTH-type transcriptional regulator aglR, P21867: HTH-type transcriptional regulator rafR; COG: COG1609 - Transcriptional regulators; PFAM: PF00532; SMART: SM00354; PROSITE: PS50932 YP_001532997.1 SWISSPROT Q08638: Beta-glucosidase A; COG: COG2723 - Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; PANTHER: GLYCOSIDE HYDROLASES (PTHR10353); PFAM: PF00232; SPRINT: PR00131; PROSITE: PS00572 YP_001532998.1 SWISSPROT P64254: Glucokinase; TIGRFAM: TIGR00749 glucokinase, proteobacterial type; COG: COG0837; PFAM: PF02685; SUPERFAMILY: SSF53067 YP_001532999.1 SWISSPROT Q55282: Manganese transport system membrane protein mntB, P44660: Probable iron transport system membrane protein HI0359; COG: COG1108 - ABC-type Mn2+/Zn2+ transport systems, permease components; PFAM: pfam00950; SUPERFAMILY: SSF81345 YP_001533000.1 SWISSPROT Q55282: Manganese transport system membrane protein mntB, P44661: Probable iron transport system membrane protein HI0360; COG: COG1108 - ABC-type Mn2+/Zn2+ transport systems, permease components; PFAM: pfam00950; SUPERFAMILY: SSF81345 YP_001533001.1 SWISSPROT P15031: Iron(III) dicitrate transport ATP-binding protein fecE, Q55281: Manganese transport system ATP-binding protein mntA, P44662: Probable iron transport system ATP-binding protein HI0361; COG: COG1121 - ABC-type Mn/Zn transport systems, ATPase component; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382; SUPERFAMILY: SSF52540; Gene3D: G3DSA:3.40.50.300 YP_001533002.1 SWISSPROT Q57449: Uncharacterized periplasmic iron-binding protein HI0362, P31304: Manganese ABC transporter substrate-binding lipoprotein [Precursor]; COG: COG0803 - ABC-type metal ion transport system, periplasmic component/surface adhesin; PFAM: PF01297; SPRINT: PR00690, PR00691; SUPERFAMILY: SSF53807; Gene3D: G3DSA:3.40.50.1980 YP_001533003.1 TIGRFAM: TIGR00738; PFAM: PF02082; SUPERFAMILY: SSF46785 YP_001533004.1 COG: COG3707 - Response regulator with putative antiterminator output domain; PFAM: PF00072, PF03861; SUPERFAMILY: SSF52172 YP_001533005.1 COG: COG0715 - ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; SUPERFAMILY: SSF53850; associated with nitrate transport system YP_001533006.1 COG: COG0715 - ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; SUPERFAMILY: SSF53850; associated with nitrate transport system YP_001533007.1 COG: COG0600 - ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; associated with nitrate transport system YP_001533008.1 TIGRFAM: TIGR01184 nitrate transport ATP-binding subunits C and D; COG: COG1116 - ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; PFAM: PF00005; SMART: SM00382; SUPERFAMILY: SSF52540; Gene3D: G3DSA:3.40.50.300; nitrate transport ATP binding subunits C and D YP_001533009.1 COG: COG1017 - Hemoglobin-like flavoprotein; PFAM: PF00042-Globin; SUPERFAMILY: Globin-like SSF46458; Gene3D: G3DSA:1.10.490.10; SWISSPROT P04252: Bacterial hemoglobin YP_001533010.1 SWISSPROT P42435: Nitrite reductase [NAD(P)H]; TIGRFAM: TIGR02374 nitrite reductase [NAD(P)H], large subunit; COG: COG1251 - NAD(P)H-nitrite reductase; PFAM: pfam00070, pfam01077, pfam03460, pfam04324 YP_001533011.1 SWISSPROT P42436: assimilatory nitrite reductase [NAD(P)H], small subunit; TIGRFAM: TIGR02378 nitrite reductase [NAD(P)H], small subunit; COG: COG2146 - Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases YP_001533012.1 SWISSPROT Q06457: Nitrate reductase; COG: COG3383 - Uncharacterized anaerobic dehydrogenase; PFAM: pfam00384, pfam01568, pfam04324, pfam04879 YP_001533013.1 SWISSPROT Q8R9M6: Anthranilate phosphoribosyltransferase; COG: COG0547 - Anthranilate phosphoribosyltransferase; PFAM: PF02885; Gene3D: G3DSA:3.40.1030.10; SUPERFAMILY: SSF47648, SSF52418; PANTHER: PTHR11922 YP_001533014.1 SWISSPROT P0AEA8: Siroheme synthase; TIGRFAM: TIGR01470, TIGR01469; PFAM: PF00590; Gene3D: G3DSA:3.40.1010.10, G3DSA:3.30.950.10 YP_001533015.1 PANTHER: PTHR10920-Ribosomal RNA methyltransferase; PIR: PIRSF005461- 23S riosomal methyltransferase; PFAM: PF01728 YP_001533016.1 COG: COG0248 - Exopolyphosphatase; SWISSPROT P25552: Guanosine-5-triphosphate,3-diphosphate pyrophosphatase; PFAM: PF02541; Gene3D: G3DSA:3.30.420.150, G3DSA:3.30.420.40; SUPERFAMILY: SSF53067 YP_001533018.1 COG:COG0685, Gene3D: G3DSA:3.20.20.220 YP_001533019.1 TIGRFAMS: TIGR01509 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; COG: COG0637 - Predicted phosphatase/phosphohexomutase; PFAM: PF00702; SPRINT: PR00413; PROSITE: PS01228; SWISSPROT Q9X0Y1: Phosphorylated carbohydrates phosphatase TM_1254, P77475: Phosphatase yqaB YP_001533020.1 catalyzes the transfer of the N5-methyl group from (6S)-methyl tetrahydrofolate to the cobalt center of a corrinoid iron-sulfur protein YP_001533023.1 COG: COG3894 - Uncharacterized metal-binding protein; PFAM: PF00111; PROSITE: PS51085; similar to ferredoxin YP_001533024.1 COG: COG0824 - Predicted thioesterase; TIGRFAM: TIGR00051-conserved hypothetical protein TIGR00051; PFAM: PF03061; SUPERFAMILY: SSF54637 YP_001533025.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001533026.1 TIGRFAM: TIGR01198 6-phosphogluconolactonase; COG: COG0363 - 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; PANTHER: PTHR11054- 6-phosphogluconolactonase YP_001533027.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001533028.1 COG: COG0535 - Predicted Fe-S oxidoreductases; PFAM: PF04055 YP_001533029.1 COG: COG1305 - Transglutaminase-like enzymes, putative cysteine proteases; PFAM: pfam01841; SMART: SM00460; SUPERFAMILY: SSF54001; transglutaminase-like YP_001533030.1 COG: COG1403 - Restriction endonuclease; PFAM: PF01844-HNH endonuclease; SMART: SM00507-HNH nucleases YP_001533031.1 COG: COG0400 - Predicted esterase; PFAM: PF02230 YP_001533032.1 similar to SWISSPROT P04395: DNA-3-methyladenine glycosylase 2, alkylbase DNA glycosidase alkA family member; COG: COG0122 - 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; PFAM: PF00730; SMART: SM00478 YP_001533033.1 SWISSPROT P21920: Precorrin-6A reductase; PFAM PF02571: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: TIGR00715; COG: COG2099 YP_001533034.1 PFAM PF01888: CbiD; SUPERFAMILY: CbiD-like; TIGRFAM: TIGR00312 cobalamin biosynthesis protein CbiD; COG: COG1903; SWISSPROT Q2W3X9: putative cobalt-precorrin-6A synthase [deacetylating], belongs to the cbiD-family YP_001533035.1 SWISSPROT P21631: Uroporphyrinogen-III C-methyltransferase; TIGRFAM: TIGR01469 uroporphyrin-III C-methyltransferase; COG: COG0007; PFAM: pfam00590; Gene3D: G3DSA:3.30.950.10, G3DSA:3.40.1010.10; PROSITE: PS00840 YP_001533036.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001533037.1 PFAM: PF07690; PROSITE: PS50850 YP_001533038.1 COG: COG1562 - Phytoene/squalene synthetase YP_001533039.1 TIGRFAM: TIGR00977 2-isopropylmalate synthase/homocitrate synthase family protein; COG: COG0119; PFAM: PF00682, PF08502; PROSITE: PS00815, PS00816; SUPERFAMILY: SSF110921, SSF51569 YP_001533041.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001533042.1 COG: COG3637 - Opacity protein and related surface antigens YP_001533043.1 PFAM: PF00106-short chain dehydrogenase; PROSITE: PS00061-Short-chain dehydrogenases/reductases family signature YP_001533044.1 SWISSPROT P39832: High-affinity zinc uptake system membrane protein znuB; PFAM: PF00950; COG: COG1108 - ABC-type Mn2+/Zn2+ transport systems, permease components; ABC-3 family; znuB YP_001533045.1 SWISSPROT P0A9X1: Zinc import ATP-binding protein znuC; COG: COG1121 - ABC-type Mn/Zn transport systems, ATPase component PFAM: PF00005; SMART: SM00382; SUPERFAMILY: SSF52540; Gene3D: G3DSA:3.40.50.300 YP_001533046.1 SWISSPROT P0AC51: Zinc uptake regulation protein; PRODOM: PD002003; PFAM: pfam01475; zur YP_001533047.1 SWISSPROT P39172: High-affinity zinc uptake system protein znuA [Precursor]; COG: COG4531 - ABC-type Zn2+ transport system, periplasmic component/surface adhesin; PFAM: PF01297; znuA YP_001533049.1 TIGRFAM: TIGR00357 methionine-R-sulfoxide reductase; COG: COG0229 - Conserved domain frequently associated with peptide methionine sulfoxide reductase; PFAM: pfam01641 YP_001533050.1 SUPERFAMILY: SSF55729; COG: COG3176 - Putative hemolysin YP_001533051.1 PFAM: PF01396, PF08378; SUPERFAMILY: SSF57783; nuclease related YP_001533052.1 SWISSPROT P0C0S1: Small-conductance mechanosensitive channel; COG: COG0668 - Small-conductance mechanosensitive channel; PFAM: PF00924; SUPERFAMILY: SSF50182, SSF82861, SSF82689 YP_001533053.1 SWISSPROT P0AC69: Glutaredoxin-4; PFAM: Glutaredoxin; TIGRFAM: TIGR00365 glutaredoxin-related protein; COG: COG0278 YP_001533055.1 PFAM: PF01722; PANTHER: PTHR12735; Gene3D: G3DSA:3.30.300.90; COG: COG0271 - Stress-induced morphogen (activity unknown); similar to bolA-like proteins YP_001533056.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001533057.1 COG: COG0488 - ATPase components of ABC transporters with duplicated ATPase domains; PFAM: PF00005; PROSITE: PS00211, PS50893; SUPERFAMILY: SSF52540; Gene3D: G3DSA:3.40.50.300 YP_001533058.1 SUPERFAMILY: SSF52540; Gene3D: G3DSA:3.40.50.300; PFAM: pfam00685; similar to sulfotransferase YP_001533059.1 COG: COG2913 - Small protein A (tmRNA-binding) YP_001533060.1 COG: COG1399 - Predicted metal-binding, possibly nucleic acid-binding protein; PFAM: PF02620 YP_001533061.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001533062.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001533063.1 SWISSPROT P0A6R0: 3-oxoacyl-[acyl-carrier-protein] synthase 3. TIGRFAM: TIGR00747 3-oxoacyl-(acyl-carrier-protein) synthase III; COG: COG0332; PFAM: PF08541, PF08545 YP_001533064.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001533065.1 PFAM: PF00376; SMART: SM00422; COG: COG0789 - Predicted transcriptional regulators; similar to MerR family regulatory protein YP_001533066.1 Catalyzes the deamination of dCTP to form dUTP YP_001533067.1 TIGRFAM: TIGR00281 segregation and condensation protein B; SWISSPROT Q65HX2: Segregation and condensation protein B; PFAM: PF04079; scpB YP_001533068.1 SWISSPROT Q87BI4: Segregation and condensation protein A; PFAM: PF02616; scpA YP_001533069.1 PFAM: PF00933; PROSITE: PS00775; SWISSPROT P75949: Beta-hexosaminidase; COG: COG1472 - Beta-glucosidase-related glycosidases YP_001533070.1 PFAM: PF05036; related to proteins involved in sporulation and cell division YP_001533071.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001533072.1 TIGRFAM: TIGR01353 deoxyguanosinetriphosphate triphosphohydrolase, putative, TIGR00277; SWISSPROT P15723: Deoxyguanosinetriphosphate triphosphohydrolase, P63934: Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG: COG0232 - dGTP triphosphohydrolase; PFAM: pfam01966 YP_001533073.1 TIGRFAM: TIGR00049 Iron-sulfur cluster assembly accessory protein; PROSITE: PS01152; PFAM: PF01521 YP_001533075.1 SWISSPROT P0ACC1: Protein methyltransferase hemK; TIGRFAM: TIGR00536 HemK family putative methylases; COG: COG2890 - Methylase of polypeptide chain release factors; PFAM: PF08241; PROSITE: PS00092; SUPERFAMILY: SSF53335 YP_001533076.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001533078.1 catalyzes the formation of putrescine from agmatine YP_001533079.1 PFAM: PF05164- Cell division protein ZapA YP_001533081.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001533082.1 PFAM: PF05661; COG: COG2354 YP_001533083.1 SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044 YP_001533085.1 SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044 YP_001533086.1 PFAM: PF00583; PROSITE: PS51186; related to acetyltransferase, GNAT family YP_001533087.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001533088.1 PFAM: PF00571; SMART: SM00116; COG: COG2905 - Predicted signal-transduction protein containing cAMP-binding and CBS domains; related to cystathionine beta synthase YP_001533089.1 COG: COG0583 - Transcriptional regulator; PFAM: PF00126, PF03466; PROSITE: PS50931; SUPERFAMILY: SSF53850, SSF46785 YP_001533090.1 SWISSPROT P28810: Methylmalonate-semialdehyde dehydrogenase [acylating]; TIGRFAM: TIGR01722 methylmalonic acid semialdehyde dehydrogenase; PANTHER: PTHR11699:SF27; PFAM: PF00171; PROSITE: PS00070; COG: COG1012 - NAD-dependent aldehyde dehydrogenases YP_001533092.1 ATP-dependent carboxylate-amine ligase YP_001533093.1 PFAM: PF00441, PF02770, PF02771; PROSITE: PS00072, PS00073; COG: COG1960 - Acyl-CoA dehydrogenases YP_001533094.1 COG: COG1024 - Enoyl-CoA hydratase/carnithine racemase; PFAM: PF00378; Gene3D: G3DSA:3.90.226.10 YP_001533095.1 TIGRFAM: TIGR01692 3-hydroxyisobutyrate dehydrogenase; PANTHER: PTHR22981; PROSITE: PS00895; PFAM: PF03446; Gene3D: G3DSA:1.10.1040.10 YP_001533096.1 COG: COG1024 - Enoyl-CoA hydratase/carnithine racemase; PFAM: PF00378; PROSITE: PS00166 YP_001533098.1 SWISSPROT Q9WZW0: tRNA pseudouridine synthase B; PRODOM: PD012454; similar to tRNA pseudouridine synthase B YP_001533099.1 SWISSPROT Q9K197: Carboxylesterase bioH, Q56841: 2-(S)-hydroxypropyl-CoM dehydrogenase YP_001533100.1 COG: COG3926 - Putative secretion activating protein; PFAM: PF05838 YP_001533101.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001533102.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001533103.1 TIGRFAM: TIGR00067 glutamate racemase; PFAM PF01177: Asp/Glu/Hydantoin racemase; PROSITE: PS00923; COG: COG0796 - Glutamate racemase YP_001533104.1 COG: COG3176-Putative hemolysin; PFAM: PF01553; SMART: SM00563; SUPERFAMILY: SSF69593 YP_001533105.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_001533106.1 SWISSPROT P30846: Uncharacterized HTH-type transcriptional regulator yafC; COG: COG0583 - Transcriptional regulator; PFAM: PF00126, PF03466; PROSITE: PS50931; SUPERFAMILY: SSF53850, SSF46785 YP_001533107.1 SUPERFAMILY: SSF53474; PANTHER: PTHR11731; Gene3D: G3DSA:3.40.50.1820; COG: COG0657 - Esterase/lipase YP_001533108.1 SWISSPROT Q99T13: Putative multidrug export ATP-binding/permease protein SAV1866; PROSITE: PS00211, PS50893, PS50929; PFAM: PF00664, PF00005; SMART: SM00382 YP_001533109.1 PFAM: PF01476 YP_001533110.1 PFAM: PF03641; TIGRFAM: TIGR00725 conserved hypothetical protein, DprA/Smf-related, family 1, TIGR00730 conserved hypothetical protein, DprA/Smf-related, family 2; SUPERFAMILY SSF102405: putative lysine decarboxylase YP_001533111.1 SWISSPROT P0A955: KHG/KDPG aldolase; PFAM: PF01081; TIGRFAM: TIGR01182; COG: COG0800 - 2-keto-3-deoxy-6-phosphogluconate aldolase YP_001533112.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001533114.1 COG: COG1092 - Predicted SAM-dependent methyltransferases; PFAM: PF03602; SUPERFAMILY: SSF53335; SWISSPROT P75876: UPF0064 protein yccW; similar to methyltransferase YP_001533116.1 SWISSPROT P25894: Uncharacterized metalloprotease yggG; PANTHER: OMA1 HOMOLOG, ZINC METALLOPEPTIDASE (PTHR22726); PFAM: PF01435 YP_001533118.1 PFAM: PF03710; COG: COG1391 - Glutamine synthetase adenylyltransferase YP_001533119.1 SWISSPROT P0ADU5: Protein ygiW [Precursor]; Gene3D: G3DSA:2.40.50.200; SUPERFAMILY: SSF101756; similar to hypothetical protein ygiW YP_001533120.1 SWISSPROT P0A9M0: ATP-dependent protease La; TIGRFAM: TIGR00763 ATP-dependent protease La, TIGR00764 lon-related putative ATP-dependent protease; COG: COG0466; PFAM: PF02190, PF00004, PF05362; SMART: SM00382; SPRINT: SM00464 YP_001533122.1 SWISSPROT P00893: Acetolactate synthase isozyme 3 large subunit; TIGRFAM: TIGR00118 acetolactate synthase, large subunit, biosynthetic type; COG: COG0028 - Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; PFAM: PF02775, PF00205, PF02776 YP_001533123.1 PROSITE: PS51257 YP_001533124.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001533125.1 SWISSPROT P0ABR7: Putative dioxygenase subunit alpha yeaW; PFAM: PF00355; SPRINT: PR00090 YP_001533126.1 PROSITE: PS00018 YP_001533127.1 TIGRFAM: TIGR02937 RNA polymerase sigma factor, sigma-70 family; COG: COG1595 - DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; PFAM: PF08281, PF04542 YP_001533128.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001533130.1 COG: COG1430 - Uncharacterized conserved protein; PFAM: PF02643 YP_001533131.1 SWISSPROT P32081: Cold shock protein cspB; COG: COG1278 - Cold shock proteins; PFAM: PF00313; SMART: SM00357; SPRINT: PR00050 YP_001533132.1 TIGRFAM: TIGR00558 pyridoxamine-phosphate oxidase; COG: COG0259; PFAM: PF01243; PROSITE: PS01064; SUPERFAMILY: SSF50475 YP_001533133.1 SWISSPROT O24990: Enoyl-[acyl-carrier-protein] reductase [NADH]; COG: COG0623 - Enoyl-[acyl-carrier-protein] reductase (NADH); PFAM: PF00106; SPRINT: PR00081 YP_001533134.1 PFAM: PF01810-LysE type translocator; COG: COG1280 - Putative threonine efflux protein; SWISSPROT P0AG38: Threonine efflux protein (rhtC) YP_001533135.1 PFAM: PF01810-LysE type translocator; COG: COG1280 - Putative threonine efflux protein; SWISSPROT P0AG38: Threonine efflux protein (rhtC) YP_001533136.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001533137.1 COG: COG0436 - Aspartate/tyrosine/aromatic aminotransferase; PFAM: PF00155; SPRINT: PR00753; Gene3D: G3DSA:3.40.640.10; SUPERFAMILY: SSF53383 YP_001533138.1 SWISSPROT P0ADY1: Peptidyl-prolyl cis-trans isomerase D; SUPERFAMILY: SSF54534, SSF81827 YP_001533139.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001533140.1 PFAM: PF04748 YP_001533141.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001533142.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001533143.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001533144.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001533145.1 SWISSPROT P12281: Molybdopterin biosynthesis protein moeA; TIGRFAM: TIGR00177; PFAM: pfam03453, pfam00994, pfam03454; COG: COG0303 - Molybdopterin biosynthesis enzyme YP_001533146.1 Represses a number of genes involved in the response to DNA damage YP_001533147.1 PFAM: PF03772; TIGRFAM: TIGR00360 YP_001533148.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001533149.1 SWISSPROT P0ABH7: Citrate synthase; TIGR01798 citrate synthase I (hexameric type); COG: COG0372; PFAM: PF00285; PROSITE: PS00480; PRINTS: PR00143 YP_001533150.1 PFAM: PF00582; PRINTS: PR01438 YP_001533151.1 PFAM PF01235: Sodium:alanine symporter family; TIGRFAM: TIGR00835 amino acid carrier protein; COG: COG1115 - Na+/alanine symporter; PRINTS: PR00175 YP_001533152.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001533153.1 PFAM PF07690: Major facilitator superfamily; PROSITE: PS50850 YP_001533154.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001533155.1 PFAM: PF06041 YP_001533156.1 PFAM PF07690: Major facilitator superfamily; PROSITE: PS50850 YP_001533157.1 PROSITE: PS00018 YP_001533158.1 PFAM: PF00196, PF03472; SMART: SM00421; PROSITE: PS50043; COG: COG2197 - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; HTH type YP_001533159.1 COG3264 - Small-conductance mechanosensitive channel; PFAM: PF00924; SUPERFAMILY: SSF50182, SSF82861, SSF82689 YP_001533160.1 COG1741 - Pirin-related protein; PFAM: PF05726, PF02678 YP_001533162.1 PFAM: PF00196, PF03472; SMART: SM00421; PROSITE: PS50043; COG: COG2197 - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; HTH type YP_001533163.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_001533165.1 TIGRFAM: TIGR00832 arsenical-resistance protein; COG: COG0798 - Arsenite efflux pump ACR3 and related permeases; PFAM: PF01758 YP_001533167.1 SWISSPROT P76041: Putative sucrose phosphorylase, P10249: Sucrose phosphorylase; COG: COG0366 - Glycosidases; PFAM: PF00128 YP_001533168.1 SWISSPROT P39646: Posphate acetyltransferase; TIGRFAM: TIGR00651; COG: COG0280; PFAM: PF01515-Phosphate acetyl/butaryl transferase YP_001533169.1 PFAM: PF05899, SUPERFAMILY: SSF51182 YP_001533170.1 SWISSPROT Q92UW5: UPF0324 membrane protein; PFAM: PF03601- conserved hypothetical protein 698; TIGRFAM: TIGR00698 conserved hypothetical integral membrane protein; COG: COG2855 - Predicted membrane protein YP_001533171.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_001533172.1 PFAM: PF01266; COG: COG0665 - Glycine/D-amino acid oxidases (deaminating) YP_001533173.1 PFAM: PF07366 YP_001533174.1 PFAM: PF00582; PRINTS: PR01438; COG: COG0589 - Universal stress protein UspA and related nucleotide-binding proteins YP_001533175.1 SWISSPROT P44543: Sialic acid TRAP transporter permease protein siaT; TIGRFAM: TIGR00786 TRAP transporter, DctM subunit; COG: COG1593 - TRAP-type C4-dicarboxylate transport system, large permease component; PFAM: PF06808-DctM-like transporters YP_001533176.1 PFAM: PF04290; DctQ component YP_001533177.1 SWISSPROT P44542: Sialic acid-binding periplasmic protein siaP; TIGRFAM: TIGR00787 tripartite ATP-independent periplasmic transporter solute receptor, DctP family; COG: COG1638 - TRAP-type C4-dicarboxylate transport system, periplasmic component; PFAM: PF03480-Bacterial extracellular solute-binding protein, family 7; siaP YP_001533178.1 SWISSPROT P77730: Uncharacterized HTH-type transcriptional repressor ydcR; COG: COG1167 - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; PFAM: PF00392, PF00155; SMART: SM00345 ; PROSITE: PS50949; GntR-type YP_001533179.1 PROSITE: PS50817 YP_001533180.1 SWISSPROT P31806: Uncharacterized protein yjeF; TIGRFAM: TIGR00197, TIGR00196; PFAM: PF03853, PF01256; COG: COG0063 - Predicted sugar kinase YP_001533181.1 SWISSPROT P0A9Z1: Nitrogen regulation protein PII-1 (glnB); PROSITE: PS00496; PFAM: PF00543 YP_001533182.1 SWISSPROT P0A9C5: Glutamine synthetase; TIGRFAM: TIGR00653 glutamine synthetase, type I; COG: COG0174 YP_001533183.1 COG: COG1765-Predicted redox protein, regulator or disulfide bond formation. PFAM: pfam02566; SUPERFAMILY: SSF82784; Gene3D: G3DSA:3.30.300.20. No sequence similiarity to protein OsmC from E.coli could be detected with Swiss-Prot BLAST. YP_001533185.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001533187.1 PFAM: pfam00515; PROSITE: PS50005, PS50293; related to tetratricopeptide-like YP_001533188.1 SWISSPROT P0ABZ1: Flagellar motor switch protein fliG; COG: COG1536 - Flagellar motor switch protein; PFAM: PF01706; PRINTS: PR00954 YP_001533189.1 SUPERFAMILY: SSF75169 YP_001533190.1 PFAM: PF02211; SUPERFAMILY: SSF50090; similar to nitrile hydratase subunit beta YP_001533191.1 PFAM: PF02211; SUPERFAMILY: SSF50090; similar to nitrile hydratase subunit beta YP_001533192.1 SWISSPROT Q7SID2: Cobalt-containing nitrile hydratase subunit alpha, P97051: Nitrile hydratase subunit alpha; PFAM: PF02979; PIR: PIRSF001426 YP_001533193.1 PFAM PF06764: Protein of unknown function DUF1223 YP_001533194.1 Catalyzes the conversion of citrate to isocitrate YP_001533195.1 SWISSPROT P0AA86: Thiol:disulfide interchange protein dsbE; TIGRFAM: TIGR00385 periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; COG: COG0526 - Thiol-disulfide isomerase and thioredoxins; PFAM: PF08534; PRINTS: PR00421 YP_001533196.1 SWISSPROT P0ABM1: Heme exporter protein C; TIGRFAM: TIGR01191 heme exporter protein CcmC; COG: COG0755 - ABC-type transport system involved in cytochrome c biogenesis, permease component; PFAM: PF01578; PRINTS: PR01386 YP_001533197.1 PFAM: PF03379-CcmB protein; TIGRFAM: TIGR01190 heme exporter protein CcmB; COG: COG2386 - ABC-type transport system involved in cytochrome c biogenesis, permease component; PRINTS: PR01414 YP_001533198.1 ATP-binding protein; required for proper cytochrome c maturation YP_001533199.1 PFAM: Protein of unknown function (DUF498/DUF598); COG: COG3737 YP_001533200.1 PFAM: PF01925; PROSITE: PS00318; related to DUF81 YP_001533201.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001533202.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001533203.1 SV; Pfam: preprotein translocase subunit, ProDom: YajC preprotein translocase subunit, TIGRFAM: YajC YP_001533205.1 PFAM: PF00805; COG: COG1357 - Uncharacterized low-complexity proteins YP_001533206.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001533207.1 TIGRFAM: TIGR02283 lytic murein transglycosylase; COG: COG2951 - Membrane-bound lytic murein transglycosylase B; PFAM: PF01471; Gene3D: G3DSA:1.10.101.10 YP_001533209.1 COG: COG5473 - Predicted integral membrane protein YP_001533210.1 SWISSPROT P31592: Glutamine synthetase 3; COG: COG0174 - Glutamine synthetase; PFAM: PF00120; PROSITE: PS00181; SUPERFAMILY: SSF54368 YP_001533211.1 SWISSPROT O87392: Glutamate synthase large subunit-like protein (glxD); PFAM: PF01645; COG: COG0069 - Glutamate synthase domain 2 YP_001533212.1 PFAM: PF01493; PIR: PIRSF006519; SWISSPROT O87391: Protein glxC; COG: COG0070 - Glutamate synthase domain 3; fwdC/fmdC family protein YP_001533213.1 PFAM: PF00310; PROSITE: PS01039; SWISSPROT O87390: Glutamine amidotransferase-like protein glxB; COG: COG0067 - Glutamate synthase domain 1; class II YP_001533214.1 PFAM: PF01381, PF07883; PROSITE: PS50943; SUPERFAMILY: SSF51182, SSF47413; COG: COG1396 - Predicted transcriptional regulators YP_001533215.1 SUPERFAMILY: SSF50952; Gene3D: G3DSA:2.120.10.30; COG: COG2133 - Glucose/sorbosone dehydrogenases YP_001533216.1 SWISSPROT P00105: Cytochrome c-554(548); PFAM: PF00034- cytochrome c; COG: COG2863 - Cytochrome c553 YP_001533217.1 PFAM: PF00440; PROSITE: PS50977; SUPERFAMILY: SSF46689, SSF48498; COG: COG1309 - Transcriptional regulator; tetR family YP_001533218.1 PFAM: PF04224-Protein of unknown function, DUF417; COG: Predicted membrane protein; SWISSPROT P75685: Inner membrane protein ykgB; DUF417 YP_001533219.1 SWISSPROT P0AC62: Glutaredoxin-3; TIGRFAM: TIGR02181 Glutaredoxin, GrxC family; COG: COG0695 - Glutaredoxin and related proteins; PFAM: PF00462-Glutaredoxin; grxC YP_001533220.1 COG: COG4325 - Predicted membrane protein YP_001533221.1 SUPERFAMILY: SSF56784 YP_001533222.1 COG: COG3825 - Uncharacterized protein conserved in bacteria YP_001533224.1 PROSITE: PS00214, PS51257 YP_001533225.1 PFAM: PF00583; PROSITE: PS51186; SUPERFAMILY: SSF55729 YP_001533226.1 COG: COG0714 - MoxR-like ATPases; PFAM: PF00004; SMART: SM00382 ; PRITNTS: PR00300 YP_001533227.1 TIGRFAM: TIGR02420 RNA polymerase-binding protein DksA; COG: COG1734 - DnaK suppressor protein; SWISSPROT P0ABS1: DnaK suppressor protein (dksA); PFAM: PF01258; PROSITE: PS01102 YP_001533228.1 COG: COG0654 - 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; PFAM: PF01266; PRINTS: PR00420 YP_001533229.1 TIGRFAM: TIGR00195 exodeoxyribonuclease III, TIGR00633 exodeoxyribonuclease III (xth); COG: COG0708 - Exonuclease III; PFAM: PF03372-Endonuclease/Exonuclease/phosphatase family; PROSITE: PS00726; xthA YP_001533230.1 TIGRFAM: TIGR01388; COG: COG0349; PFAM: PF01612; SMART: SM00474; PROSITE: PS50967; SUPERFAMILY: SSF53098; rnd YP_001533231.1 TIGRFAM: TIGR00639 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; COG: COG0299 - Folate-dependent phosphoribosylglycinamide formyltransferase PurN; PFAM PF00551: Formyl transferase YP_001533232.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001533233.1 PFAM: PF08238; SMART: SM00671; SUPERFAMILY: SSF81901 YP_001533234.1 COG: COG1017 - Hemoglobin-like flavoprotein; PFAM: PF00042-Globin; SUPERFAMILY: Globin-like SSF46458; Gene3D: G3DSA:1.10.490.10; SWISSPROT P04252: Bacterial hemoglobin YP_001533235.1 COG: COG3287 - Uncharacterized conserved protein; PFAM: PF08495 YP_001533236.1 similar to to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); highly conserved LOV consensus region including the photoactive Cys. TIGRFAM: TIGR00229 PAS domain S-box; COG: COG0642 - Signal transduction histidine kinase; SMART: SM00091: PAS domain; SM00086: PAC motif, SM00388: Histidine kinase-like ATPases, SM00448 : cheY-homologous receiver domain; PROSITE: PS50112: PAS repeat profile, PS50113: PAC domain profile, PS50110: Response regulatory domain profile, PS50109: Histidine kinase domain profile; PFAM: PF00072: Response regulator receiver domain, PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, PF00512: His Kinase A (phosphoacceptor) domain, PF08447: PAS fold YP_001533237.1 COG: COG2197 - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: PF00196, PF00072; PROSITE: PS50043, PS50110; SMART: SM00448 ; SUPERFAMILY: SSF52172 YP_001533238.1 PFAM: PF00353 YP_001533239.1 SWISSPROT P11759: GDP-mannose 6-dehydrogenase; COG: COG1004 - Predicted UDP-glucose 6-dehydrogenase; PROSITE: PS00059; PFAM: PF03721, PF00984, PF03720 YP_001533240.1 SWISSPROT P07874: Alginate biosynthesis protein algA; TIGRFAM: TIGR01479 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836 - Mannose-1-phosphate guanylyltransferase; PFAM: PF01050, PF00483 YP_001533241.1 SWISSPROT Q52463: Glycosyltransferase alg8. Possibly a processive enzyme that polymerizes GDP-mannuronic acid. No evidence at protein level but the colocation with algA and algG indicates an involvement in alginate biosynthesis. YP_001533242.1 SWISSPROT P46682: p-hydroxybenzoic acid efflux pump subunit aaeA; related to efflux pump protein YP_001533243.1 SWISSPROT P26276: Phosphomannomutase/phosphoglucomutase; COG: COG1109 - Phosphomannomutase; PFAM: PF02880, PF02879, PF02878, PF00408; PROSITE: PS00710 YP_001533244.1 SWISSPROT Q887Q8: alginate biosynthesis protein algF (precursor). No evidence at protein level and low similarity but the colocation with algC, algA and algD indicates an involvement in alginate biosynthesis.; similar to alginate biosynthesis protein algF YP_001533245.1 COG: COG1696 - Predicted membrane protein involved in D-alanine export; PFAM: PF03062 YP_001533246.1 SWISSPROT Q51393 YP_001533247.1 SWISSPROT Q88NDO; similar to alginate biosynthesis protein algX YP_001533248.1 PFAM: PF00589; Gene3D: G3DSA:1.10.443.10; similar to prophage integrase YP_001533249.1 SUPERFAMILY: SSF46955; PFAM: PF00376 YP_001533250.1 PROSITE: PS00039 YP_001533254.1 PS00527: Ribosomal protein S14 signature.; similar to ribosomal protein YP_001533256.1 PFAM: PF00665; PROSITE: PS50994; SUPERFAMILY: SSF53098; COG: COG2801 - Transposase and inactivated derivatives YP_001533257.1 PFAM: PF01527-Transposase YP_001533260.1 PROSITE: PS00093; PFAM: PF01555 YP_001533261.1 PROSITE: PS00093; PFAM: PF01555 YP_001533263.1 PFAM: PF00753 YP_001533264.1 COG: COG0642 - Signal transduction histidine kinase; PFAM: PF02518, PF00672, PF00512 YP_001533267.1 TIGRFAM: TIGR02122 TRAP transporter solute receptor, TAXI family; COG: COG2358 - TRAP-type uncharacterized transport system, periplasmic component; Gene3D: G3DSA:3.40.190.10 ; SUPERFAMIYLY: SSF53850 YP_001533268.1 COG: COG3267 - Type II secretory pathway, component ExeA (predicted ATPase); SMART: SM00382; SUPERFAMILY: SSF52540 YP_001533269.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001533270.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_001533271.1 PFAM: PF04340 - Protein of unknown function, DUF484 YP_001533272.1 PFAM: PF00892; SUPERFAMILY: SSF103481 YP_001533274.1 COG: COG0625 - Glutathione S-transferase; PFAM: PF02798, PF00043; SUPERFAMILY: SSF47616, SSF52833; SWISSPROT Q46845: Uncharacterized GST-like protein yghU YP_001533275.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001533277.1 COG: COG0492 - Thioredoxin reductase; PFAM: PF00027, PF00070; PROSITE: PS50042; SMART: SM00100; PRINTS: PR00469, PR00419, PR00368 YP_001533278.1 TIGRFAM: TIGR01620 conserved hypothetical protein; COG: COG3768 - Predicted membrane protein; PFAM: pfam05128; family DUF697 YP_001533279.1 PFAM: PF04317-YcjX-like family, DUF463; SWISSPROT P76046: Uncharacterized protein ycjX; COG: COG3106 - Predicted ATPase; DUF463 YP_001533280.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001533281.1 COG: COG0600 - ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; PFAM: PF00528; PROSITE: PS50928 YP_001533282.1 COG: COG1116 - ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001533283.1 PFAM: PF09084-NMT1/THI5 like; COG: COG0715 - ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_001533284.1 PFAM: PF08885 YP_001533285.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001533286.1 SUPERFAMILY: S-adenosyl-L-methionine-dependent methyltransferases; PFAM: PF05711 -Macrocin-O-methyltransferase (TylF) YP_001533287.1 COG: COG1079 - Uncharacterized ABC-type transport system, permease component; PFAM: PF02653 YP_001533288.1 COG4603 - ABC-type uncharacterized transport system, permease component; PFAM: PF02653 YP_001533289.1 SWISSPROT P04983: Ribose import ATP-binding protein rbsA; COG: COG3845 - ABC-type uncharacterized transport systems, ATPase components; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001533290.1 COG: COG1744 - Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein; PFAM: PF02608; PROSITE: PS00024 YP_001533292.1 SUPERFAMILY: SSF52540; similar to hydrolase YP_001533293.1 PFAM: PF00529; COG: COG1566: Multidrug resistance efflux pump; related to HlyD family secretion proteins YP_001533295.1 COG: COG3509 - Poly(3-hydroxybutyrate) depolymerase; Gene3D: G3DSA:3.40.50.1820; SUPERFAMILY: SSF53474 YP_001533296.1 PFAM: PF00106-short chain dehydrogenase; PRINTS: PR00081; COG: COG0300 - Short-chain dehydrogenases of various substrate specificities YP_001533297.1 PFAM: PF00106, PF01370; PRINTS: PR00081; Gene3D: G3DSA:3.40.50.720; COG: COG1028 - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_001533298.1 PFAM: PF01370; COG: COG0451 - Nucleoside-diphosphate-sugar epimerases YP_001533299.1 COG: COG3063 - Tfp pilus assembly protein PilF; PFAM: PF00515 Tetratricopeptide repeat 1, PF07719 Tetratricopeptide repeat 2; PROSITE: PS50005-TPR repeat profile, PS50293-TPR repeat region circular profile; SMART: SM00028-Tetratricopeptide repeats; similar to tetratricopeptide repeat superfamily proteins YP_001533300.1 COG: COG0451 - Nucleoside-diphosphate-sugar epimerases; PFAM: PF01370; PROSITE: PS00178, PS00061; Gene3D: G3DSA:3.40.50.720 YP_001533301.1 PFAM: PF01663-Type I phosphodiesterase / nucleotide pyrophosphatase; Gene3D: G3DSA:3.40.720.10-Alkaline Phosphatase, subunit A; SUPERFAMILY: Alkaline phosphatase-like YP_001533302.1 PROSITE: PS50075; SUPERFAMILY: ACP-like; similar to acyl carrier protein YP_001533303.1 SWISSPROT Q03133: Erythronolide synthase, modules 5 and 6; Q03131: Erythronolide synthase, modules 1 and 2; Q03132: Erythronolide synthase, modules 3 and 4; PFAM: PF01648, PF00109, PF02801, PF00698; TIGRFAM: TIGR00556 phosphopantethiene--protein transferase domain; COG: COG3321 - Polyketide synthase modules and related proteins YP_001533304.1 SWISSPROT: Q03131: Erythronolide synthase, modules 1 and 2; Q03132: Erythronolide synthase, modules 3 and 4; PFAM: PF03060, PF08659, PF00109, PF02801, PF00698; TIGRFAM: TIGR02813 polyketide-type polyunsaturated fatty acid synthase PfaA; COG: COG3321 - Polyketide synthase modules and related proteins YP_001533305.1 TIGRFAM: TIGR01681 HAD-superfamily phosphatase, subfamily IIIC; TIGR01686 FkbH-like domain; COG: COG3882 - Predicted enzyme involved in methoxymalonyl-ACP biosynthesis; SUPERFAMILY: SGNH hydrolase, HAD-like; hydrolase / phosphatase related YP_001533306.1 SUPERFAMILY: SSF52540 YP_001533307.1 SWISSPROT P0A9P0: Dihydrolipoyl dehydrogenase; PFAM: PF00364, PF00070, PF02852, PF07992; PROSITE: PS50968, PS00189, PS00076; PRINTS: PR00945, PR00411, PR00368; TIGRFAM: TIGR01350 dihydrolipoamide dehydrogenase; COG: COG1249 - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes YP_001533308.1 TIGRFAM: TIGR01348 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COG: COG0508 - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; PFAM: PF02817 YP_001533309.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001533310.1 TIGRFAM: TIGR00786 TRAP transporter, DctM subunit; COG: COG4664 - TRAP-type mannitol/chloroaromatic compound transport system, large permease component; PFAM: PF04290, PF06808 YP_001533311.1 PFAM: PF03480-Bacterial extracellular solute-binding protein, family 7; COG: COG4663 - TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component YP_001533312.1 SWISSPROT P0ACL9: Pyruvate dehydrogenase complex repressor (pdhR); COG: COG2186 - Transcriptional regulators; PFAM: PF07729, PF00392; SMART: SM00345; PROSITE: PS50949; Gene3D: G3DSA:1.10.10.10; SUPERFAMILY: SSF46785 YP_001533313.1 PFAM PF07726: ATPase family associated with various cellular activities (AAA); SMART: SM00382; COG: COG0714 - MoxR-like ATPases; related to ATPase (AAA) YP_001533314.1 COG: COG3864 - Uncharacterized protein conserved in bacteria YP_001533316.1 PFAM: PF00294; PRINTS: PR00990 YP_001533317.1 PFAM: PF01094-Receptor family ligand binding region; PROSITE: PS51257; SWISSPROT P21175: Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [Precursor] (braC); COG: COG0683 - ABC-type branched-chain amino acid transport systems, periplasmic component YP_001533318.1 PFAM: PF02653-Branched-chain amino acid transport system / permease component; COG: COG4177 - ABC-type branched-chain amino acid transport system, permease component YP_001533319.1 SWISSPROT P0AEX7: High-affinity branched-chain amino acid transport system permease protein livH; PFAM: PF02653-Branched-chain amino acid transport system / permease component; COG: COG4177 - ABC-type branched-chain amino acid transport system, permease component YP_001533320.1 SWISSPROT P22731: High-affinity branched-chain amino acid transport ATP-binding protein livF; PFAM: PF00005; PROSITE: PS50893; SMART: SM00382 YP_001533321.1 SWISSPROT Q58663: branched-chain amino acid transport ATP-binding protein livG; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001533322.1 PFAM: PF00248 YP_001533324.1 SWISSPROT P76114: Uncharacterized HTH-type transcriptional regulator yncC; PFAM: PF07729, PF00392; Gene3D: G3DSA:1.10.10.10; COG: COG1802 - Transcriptional regulators YP_001533325.1 COG: COG0667 - Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); PFAM: PF00248, PF01042; PRINTS: PR00069; SUPERFAMILY: SSF51430 YP_001533326.1 TIGRFAM: TIGR00178 isocitrate dehydrogenase, NADP-dependent, monomeric type; COG: COG2838 - Monomeric isocitrate dehydrogenase; PFAM PF03971: Monomeric isocitrate dehydrogenase YP_001533327.1 similar to molybdenum import ATP-binding protein modC2 YP_001533329.1 PFAM: PF00529; COG: COG1566: Multidrug resistance efflux pump; related to HlyD family secretion proteins YP_001533330.1 PFAM: PF01636; SUPERFAMILY: SSF56112; COG: COG0510 - Predicted choline kinase involved in LPS biosynthesis YP_001533331.1 PROSITE: PS50893, PS50929; PFAM: PF00664, PF00005; SMART: SM00382 YP_001533332.1 PFAM: PF00534; related to glycosyl transferase group 1 YP_001533333.1 PFAM: PF00534 YP_001533334.1 COG: COG4671 - Predicted glycosyl transferase; SUPERFAMILY: SSF53756 UDP-Glycosyltransferase/glycogen phosphorylase; Gene3D: G3DSA:3.40.50.2000 YP_001533336.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001533337.1 SWISSPROT P09099: Xylose kinase; PFAM: PF00370, PF02782; TIGRFAM: TIGR01312 D-xylulose kinase; COG: COG1070 - Sugar (pentulose and hexulose) kinases YP_001533338.1 SWISSPROT P04983: Ribose import ATP-binding protein rbsA; COG: COG1129 - ABC-type sugar transport system, ATPase component, ATPase components; PFAM: PF00005; PROSITE: PS50893; SMART: SM00382 YP_001533339.1 SWISSPROT P0AGI4: Xylose transport system permease protein xylH; COG: COG4214 - ABC-type xylose transport system, permease component; PFAM: PF02653 YP_001533340.1 SWISSPROT P37387: D-xylose-binding periplasmic protein [Precursor]; TIGRFAM: TIGR02634 D-xylose ABC transporter, substrate-binding protein; COG: COG4213 - ABC-type xylose transport system, periplasmic component YP_001533341.1 SWISSPROT Q44406: Xylose repressor xylR. The entry has no evidence at protein level, but the colocation with the xylose operon supports the annotation. COG: COG1940 - Transcriptional regulator/sugar kinase; PFAM: PF00480 YP_001533342.1 SUPERFAMILY: SSF69318 YP_001533343.1 TIGRFAM: TIGR01409 YP_001533344.1 PFAM: PF01794 YP_001533345.1 PFAM: PF03150; Gene3D: G3DSA:1.10.760.10; PROSITE: PS51007 YP_001533346.1 DK; SWISSPROT O34627: Blue-light photoreceptor; PFAM: PF08447; SMART: SM00086, SM00091; PROSITE: PS50112, PS50113. TD; 1) similar to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); 2) highly conserved LOV consensus region including the photoactive Cys YP_001533347.1 PFAM: PF00293; Gene3D: G3DSA:3.90.79.10; SUPERFAMILY: SSF55811; similar to NUDIX hydrolase YP_001533348.1 SWISSPROT P0ACL0: Glycerol-3-phosphate regulon repressor; COG: COG1349 - Transcriptional regulators of sugar metabolism; PFAM: PF08220, PF00455; PROSITE: PS00894, PS51000; SMART: SM00420 YP_001533349.1 TIGRFAM: TIGR01098 phosphonates-binding periplasmic protein; COG: COG3221 - ABC-type phosphate/phosphonate transport system, periplasmic component; SUPERFAMILY: SSF53850 YP_001533350.1 TIGRFAM: TIGR02315 phosphonate ABC transporter, ATP-binding protein; DK; COG3638 - ABC-type phosphate/phosphonate transport system, ATPase component; PFAM: PF00005; SMART: SM00382; PROSITE: PS00211, PS50893, PS51249 YP_001533351.1 TIGRFAM: TIGR01097 phosphonate ABC transporter, permease protein; COG: COG3639 - ABC-type phosphate/phosphonate transport system, permease component; PFAM: PF00528; PROSITE: PS50928; associated with phosphonates transport system YP_001533352.1 TIGRFAM: TIGR01097 phosphonate ABC transporter, permease protein; COG: COG3639 - ABC-type phosphate/phosphonate transport system, permease component; PFAM: PF00528; PROSITE: PS50928; associated with phosphonates transport system YP_001533353.1 PFAM: PF00702; COG: COG0647 - Predicted sugar phosphatases of the HAD superfamily; TIGRFAM: TIGR01459 HAD-superfamily class IIA hydrolase; TIGR01460 Haloacid Dehalogenase Superfamily Class (subfamily) IIA; similar to nagD, associated with phosphonates transport system YP_001533354.1 SWISSPROT P0AG80: sn-glycerol-3-phosphate-binding periplasmic protein ugpB [Precursor]; COG: COG1653 - ABC-type sugar transport system, periplasmic component; PFAM: PF01547; SUPERFAMILY: SSF53850; Gene3D: G3DSA:3.40.190.10 YP_001533355.1 SWISSPROT P10905: sn-glycerol-3-phosphate transport system permease protein ugpA; PFAM: PF00528; PROSITE: PS50928; COG1175 - ABC-type sugar transport systems, permease components YP_001533356.1 SWISSPROT P10906: sn-glycerol-3-phosphate transport system permease protein ugpE; PFAM: PF00528; PROSITE: PS50928; COG: COG0395 - ABC-type sugar transport system, permease component YP_001533357.1 SWISSPROT P10907: sn-glycerol-3-phosphate import ATP-binding protein ugpC; PFAM: PF00005, PF08402; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001533359.1 COG: COG0069 - Glutamate synthase domain 2; PFAM: PF01645; Gene3D: G3DSA:3.20.20.70 YP_001533360.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001533361.1 SWISSPROT Q9HTX3: Probable binding protein component of ABC iron transporter PA5217 [Precursor]; COG: COG1840 - ABC-type Fe3+ transport system, periplasmic component; PFAM: PF01547; SUPERFAMILY: SSF53850; Gene3D: G3DSA:3.40.190.10 YP_001533362.1 no shine dalgarno sequence, no Swiss-Prot or InterPro Hits, no similar proteins in ncbi database. Probably pseudogene??? YP_001533363.1 PFAM: PF00528-Binding-protein-dependent transport system inner membrane component; COG: COG1178 - ABC-type Fe3+ transport system, permease component; PROSITE: PS50928 YP_001533364.1 PFAM: PF01925 YP_001533365.1 PFAM: PF07385-Protein of unknown function (DUF1498); COG: COG3822 - ABC-type sugar transport system, auxiliary component YP_001533366.1 COG: COG1540 - Uncharacterized proteins, homologs of lactam utilization protein B; PFAM: PF03746; SWISPROT Q5LMA4: UPF0271 protein SPO3659 YP_001533367.1 PFAM: PF02626; SMART: SM00797; TIGRFAM: TIGR00724 biotin-dependent carboxylase uncharacterized domain; COG: COG1984 - Allophanate hydrolase subunit 2 YP_001533368.1 TIGRFAM: TIGR00370 conserved hypothetical protein TIGR00370; COG: COG2049 - Allophanate hydrolase subunit 1; PFAM: PF02682; SMART: SM00796 YP_001533369.1 SWISSPROT P0ACP7: HTH-type transcriptional repressor purR; PFAM: PF00356, PF00532; SMART: SM00354; PROSITE: PS50932; SUPERFAMILY: SSF47413; COG: COG1609 - Transcriptional regulators YP_001533371.1 PFAM: PF03480; TIGRFAM: TIGR01409; COG: COG1638 - TRAP-type C4-dicarboxylate transport system, periplasmic component; SWISSPROT P37735: C4-dicarboxylate-binding periplasmic protein [Precursor] YP_001533372.1 COG: COG3090 - TRAP-type C4-dicarboxylate transport system, small permease component; PFAM: PF04290; PROSITE: PS00430 YP_001533373.1 PFAM: PF06808-DctM-like transporters; TIGRFAM: TIGR00786 TRAP transporter, DctM subunit; COG: COG1593 - TRAP-type C4-dicarboxylate transport system, large permease component YP_001533374.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001533375.1 COG: COG1028 - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); PFAM: PF00106; PROSITE: PS00061; PRINTS: PR00080, PR00081 YP_001533376.1 PFAM: PF00107, PF08240; SUPERFAMILY: SSF50129; PANTHER: PTHR11695: Alcohol dehydrogenase related YP_001533377.1 SWISSPROT P42604: Altronate hydrolase; similar to altronate hydrolase YP_001533378.1 COG: COG2721 - Altronate dehydratase; PFAM: PF04295 YP_001533379.1 COG: COG2055 - Malate/L-lactate dehydrogenases; PFAM: PF02615; SUPERFAMILY: SSF89733 L-sulfolactate dehydrogenase-like YP_001533380.1 SWISSPROT P37903: Universal stress protein F; PFAM: PF00582 Universal stress protein family; PRINTS: PR01438; SUPERFAMILY: Adenine nucleotide alpha hydrolases-like; COG: COG0589 - Universal stress protein UspA and related nucleotide-binding proteins YP_001533381.1 SWISSPROT Q9APM5: Taurine--pyruvate aminotransferase; COG: COG0161 - Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: PF00202; PROSITE: PS00600 YP_001533383.1 SWISSPROT P94426: HTH-type transcriptional regulatory protein gabR; COG: COG1167 - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; PFAM: PF00392, PF00155; SMART: SM00345; PROSITE: PS50949 YP_001533384.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_001533385.1 PROSITE: PS51257; COG: COG3218 - ABC-type uncharacterized transport system, auxiliary component; related to membrane lipoprotein YP_001533386.1 PFAM: PF02470; COG: COG1463 - ABC-type transport system involved in resistance to organic solvents, periplasmic component YP_001533387.1 COG: COG1127 - ABC-type transport system involved in resistance to organic solvents, ATPase component; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001533388.1 TIGRFAM: TIGR00056 conserved hypothetical integral membrane protein; COG: COG0767 - ABC-type transport system involved in resistance to organic solvents, permease component; PROSITE: PS50801; PFAM: PF02405; SUPERFAMILY: SSF52091 YP_001533390.1 COG: COG4256; similar to hemin uptake protein YP_001533392.1 COG: COG0123 - Deacetylases, including yeast histone deacetylase and acetoin utilization protein; PFAM: PF00850; PRINTS PR01270 YP_001533393.1 COG: COG0386 - Glutathione peroxidase; SWISSPROT P99097: Glutathione peroxidase homolog bsaA; PFAM: PF00255; PIR: PIRSF000303; PROSITE: PS00460; PRINTS: PR01011; Gene3D: G3DSA:3.40.30.10 YP_001533394.1 PFAM: PF00293; PRINTS: PR00502; Gene3D: G3DSA:3.90.79.10 YP_001533395.1 COG: COG5319 - Uncharacterized protein conserved in bacteria; PFAM: PF06676-Protein of unknown function (DUF1178) YP_001533396.1 COG: COG1028 - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_001533397.1 COG: COG0645 - Predicted kinase; similar to adenylyl sulfate kinase YP_001533398.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001533399.1 SWISSPROT P26512: Aspartokinase; TIGRFAM: TIGR00656 aspartate kinase, monofunctional class, TIGR00657 aspartate kinase; COG: COG0527 - Aspartokinases YP_001533400.1 SWISSPROT P08839: Phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: TIGR01417 phosphoenolpyruvate-protein phosphotransferase; COG: COG3605 - Signal transduction protein containing GAF and PtsI domains; PFAM: pfam02896, pfam05524, pfam00391, pfam01590; SMART: SM00065 YP_001533401.1 PFAM: PF00092; SMART: SM00327; PROSITE: PS50234; PRINTS: PR00453; related to von Willebrand factor type A YP_001533402.1 COG: COG3153 - Predicted acetyltransferase; PFAM: PF00583; PROSITE: PS51186; related to acetyltransferase, GNAT family YP_001533403.1 COG: COG1853 - Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; SUPERFAMILY: FMN-binding split barrel; Gene3D: Electron Transport, Fmn-binding Protein; Chain A YP_001533405.1 SWISSPROT P0AFR2: Putative sulfate transporter ychM; COG: COG0659 - Sulfate permease and related transporters (MFS superfamily); PFAM: PF01740, PF00916; PROSITE: PS50801 YP_001533406.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate YP_001533407.1 COG: COG4321 - Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis YP_001533408.1 TIGRFAM: TIGR00068; COG: COG0346 - Lactoylglutathione lyase and related lyases; PFAM: PF00903-Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; similar to Lactoylglutathione lyase YP_001533410.1 COG: COG2303 - Choline dehydrogenase and related flavoproteins; PFAM: PF00732 YP_001533411.1 SUPERFAMILY: SSF51101 YP_001533412.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001533413.1 COG: COG3439 - Uncharacterized conserved protein; PFAM: PF03625; SUPERFAMILY: TT1751-like YP_001533414.1 COG: COG0277 - FAD/FMN-containing dehydrogenases; PFAM: PF02913, PF01565 YP_001533415.1 COG: COG2220 - Predicted Zn-dependent hydrolases of the beta-lactamase fold; related to metal-dependent hydrolase/oxidoreductase YP_001533416.1 TIGRFAM: TIGR00419 triosephosphate isomerase; COG: COG0149; PFAM: PF00121; PROSITE: PS00171 YP_001533417.1 COG: COG0583 - Transcriptional regulator; PFAM: PF00126, PF03466; PROSITE: PS50931; SUPERFAMILY: SSF53850, SSF46785; lysR family YP_001533418.1 SWISSPROT P0AEZ1: 5,10-methylenetetrahydrofolate reductase; PFAM: PF02219- Methylenetetrahydrofolate reductase; TIGRFAM: TIGR00676 5,10-methylenetetrahydrofolate reductase, prokaryotic form; COG: COG0685 - 5,10-methylenetetrahydrofolate reductase YP_001533419.1 COG: COG2863 - Cytochrome c553; PROSITE: PS51007; Gene3D: G3DSA:1.10.760.10 ; SUPERFAMILY: SSF46626 YP_001533420.1 COG: COG2133 - Glucose/sorbosone dehydrogenases; SUPERFAMILY: Soluble quinoprotein glucose dehydrogenase; Gene3D: G3DSA:2.120.10.30 YP_001533421.1 COG: COG2050 - Uncharacterized protein, possibly involved in aromatic compounds catabolism; PFAM: PF03061; TIGRFAM: TIGR00369; related to thioesterase YP_001533422.1 COG: COG3673 - Uncharacterized conserved protein; PROSITE: PS00120 YP_001533423.1 TIGRFAM: TIGR02595 YP_001533424.1 SWISSPROT P19919: Carbon monoxide dehydrogenase large chain; COG: COG1529 - Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; PFAM: pfam02738, pfam01315 YP_001533425.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001533426.1 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate YP_001533428.1 COG: COG0075 - Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: PF00266 YP_001533429.1 SUPERFAMILY: SSF53448-Nucleotide-diphospho-sugar transferases; PFAM: PF00535-Glycosyl transferase family 2; COG: COG0463 - Glycosyltransferases involved in cell wall biogenesis YP_001533430.1 COG: COG0354 - Predicted aminomethyltransferase related to GcvT; PFAM: PF08669, PF01571; similar to aminomethyltransferase YP_001533432.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001533434.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001533436.1 SWISSPROT P02930: Outer membrane protein tolC [Precursor]; TIGRFAM: TIGR01844 type I secretion outer membrane protein, TolC family; COG: COG1538 - Outer membrane protein; PFAM: PF02321 YP_001533437.1 TIGRFAM: TIGR00080 protein-L-isoaspartate(D-aspartate) O-methyltransferase; COG: COG2518 - Protein-L-isoaspartate carboxylmethyltransferase; PFAM: PF01135; pcm YP_001533438.1 PFAM: PF00589; SUPERFAMILY: SSF56349; Gene3D: G3DSA:1.10.443.10; COG: COG4974 - Site-specific recombinase XerD YP_001533439.1 SUPERFAMILY: SSF52540 YP_001533440.1 PFAM: PF01555; related to DNA methylase N4/N6 YP_001533441.1 PFAM: PF01527-Transposase YP_001533442.1 COG: COG2801 - Transposase and inactivated derivatives; PFAM: PF00665; PROSITE: PS50994; SUPERFAMILY: SSF53098 YP_001533443.1 PFAM: PF01555; PROSITE: PS00092; SUPERFAMILY: SSF53335; related to DNA methylase N6 YP_001533444.1 PFAM: PF01381; PROSITE: PS50943; SMART: SM00530; SUPERFAMILY: SSF47413; Gene3D: G3DSA:1.10.260.40; related to HTH-type lambda repressor YP_001533446.1 COG: COG0025 - NhaP-type Na+/H+ and K+/H+ antiporters; PFAM: PF00027, PF00999; SMART: SM00100; PROSITE: PS50042; related to sodium/hydrogen exchanger YP_001533447.1 COG: COG3616 - Predicted amino acid aldolase or racemase; PFAM: PF01168; related to alanine racemase YP_001533448.1 PFAM: PF04227- Indigoidine synthase A like protein; SUPERFAMILY SSF110581: Indigoidine synthase A-like YP_001533449.1 SWISSPROT P37051: Formyltetrahydrofolate deformylase; TIGRFAM: TIGR00655; COG: COG0788; PFAM: PF00551, PF01842; PRINTS: PR01575; PIR: PIRSF036480- formyltetrahydrofolate deformylase YP_001533450.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001533451.1 SWISSPROT O87386: Sarcosine oxidase subunit alpha; TIGRFAM: TIGR01375 sarcosine oxidase, gamma subunit family, heterotetrameric form; COG: COG4583 - Sarcosine oxidase gamma subunit; PFAM: PF04268: SUPERFAMILY: SSF103025 YP_001533452.1 SWISSPROT Q46337: Sarcosine oxidase subunit alpha; TIGRFAM: TIGR01372 sarcosine oxidase, alpha subunit family, heterotetrameric form; COG: COG0404 - Glycine cleavage system T protein (aminomethyltransferase); PFAM: PF01571, PF08669, PF07992 YP_001533453.1 SWISSPROT Q46336: Sarcosine oxidase subunit delta; PFAM: Sarcosine oxidase, delta subunit family; TIGRFAM: TIGR01374; COG: COG4311 - Sarcosine oxidase delta subunit; delta subunit (soxD) YP_001533454.1 SWISSPROT P40875: sarcosine oxidase subunit beta; PFAM: PF01266-FAD dependent oxidoreductase; TIGRFAM: TIGR01373-Sarcosine oxidase, beta subunit, heterotetrameric; COG: COG0665 - Glycine/D-amino acid oxidases (deaminating) YP_001533455.1 COG: COG4977 - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; PFAM: PF00165, PF01965; SMART: SM00342; PROSITE: PS01124; SUPERFAMILY: SSF46689; Gene3D: G3DSA:1.10.10.60; AraC family YP_001533456.1 TIGRFAM: TIGR00842 - choline/carnitine/betaine transport; COG: COG1292 - Choline-glycine betaine transporter; PFAM: PF02028-BCCT family transporter YP_001533457.1 SWISSPROT P69874: Spermidine/putrescine import ATP-binding protein potA; COG: COG3842-ABC-type spermidine/putrescine transport systems, ATPase components; PFAM: PF00005, PF08402; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001533458.1 SWISSPROT P0AFK6: Spermidine/putrescine transport system permease protein potC; COG: COG1177 - ABC-type spermidine/putrescine transport system, permease component II; PFAM: PF00528; PROSITE: PS50928 YP_001533459.1 SWISSPROT P0AFK4: Spermidine/putrescine transport system permease protein potB; COG: COG1176-ABC-type spermidine/putrescine transport system, permease component I; PFAM: pfam00528; PROSITE: PS50928 YP_001533460.1 COG: COG0687 - Spermidine/putrescine-binding periplasmic protein; PRINTS: PR00909; SWISSPROT P0AFK9: Spermidine/putrescine-binding periplasmic protein [Precursor]; similar to spermidine/putrescine binding periplasmic protein (potD) YP_001533461.1 PFAM: PF02633; COG: COG1402 - Uncharacterized protein, putative amidase; related to creatininase YP_001533462.1 COG: COG0583 - Transcriptional regulator; PFAM: PF00126, PF03466; PROSITE: PS50931; SUPERFAMILY: SSF53850, SSF46785; lysR family YP_001533463.1 SWISSPROT P38488: Creatinase; COG: COG0006 - Xaa-Pro aminopeptidase; PFAM: PF00557, PF01321 YP_001533464.1 SUPERFAMILY: SSF51182 YP_001533465.1 PFAM PF04403: Paraquat-inducible protein A; similar to paraquat inducible protein A YP_001533466.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001533467.1 COG: COG1286 - Uncharacterized membrane protein, required for colicin V production; PFAM: PF02674-Colicin V production protein YP_001533468.1 no database hits, no shine dalgarno. Pseudogene?? YP_001533469.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001533470.1 COG: COG3543 - Uncharacterized conserved protein; PFAM: PF06935-Protein of unknown function YP_001533471.1 COG: COG1268 - Uncharacterized conserved protein; PFAM: PF02632-BioY family; PIR: PIRSF016661- uncharacterized biotin biosynthesis protein, BioY type YP_001533472.1 COG: COG4221 - Short-chain alcohol dehydrogenase of unknown specificity; PFAM: PF00106; PRINTS: PR00081 YP_001533473.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001533474.1 TIGRFAM: TIGR00080 protein-L-isoaspartate(D-aspartate) O-methyltransferase; COG: COG2518 - Protein-L-isoaspartate carboxylmethyltransferase; PFAM: PF01135; PROSITE: PS01279 YP_001533475.1 COG: COG0739 - Membrane proteins related to metalloendopeptidases; PFAM: PF01476, PF01551; SMART: SM00257; SUPERFAMILY: SSF51261; related to metalloprotease YP_001533476.1 SWISSPROT P31125: Probable amino-acid metabolite efflux pump; P0ABT8: Uncharacterized inner membrane transporter yiJE; PFAM: PF00892; SUPERFAMILY: SSF103481; related to multidrug resistance efflux transporter YP_001533477.1 PFAM: PF00999; COG: COG0025 - NhaP-type Na+/H+ and K+/H+ antiporters; related to sodium/hydrogen exchanger YP_001533478.1 PFAM: PF04391 YP_001533479.1 SWISSPROT P0A9A9: Ferric uptake regulation protein (fur); COG: COG0735 - Fe2+/Zn2+ uptake regulation proteins; PFAM: PF01475; SUPERFAMILY: SSF46785 YP_001533480.1 COG: COG1741 - Pirin-related protein; PFAM: PF02678, PF05726; SUPERFAMILY: SSF51182 YP_001533481.1 SWISSPROT P75823: Low specificity L-threonine aldolase; O07051: L-allo-threonine aldolase COG: COG2008 - Threonine aldolase; PFAM: PF01212; SUPERFAMILY: SSF53383 YP_001533482.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001533483.1 PFAM: PF05239; related to PRC-barrel YP_001533485.1 SWISSPROT Q68XV0: S-adenosylmethionine uptake transporter; PFAM: pfam00892; COG: COG5006 - Predicted permease, DMT superfamily YP_001533486.1 COG: COG3542 - Uncharacterized conserved protein; PFAM: PF06172 Cupin superfamily (DUF985) YP_001533487.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001533488.1 Swiss-Prot: P0AGJ9-Tyrosyl-tRNA synthetase TIGRFAM: tyrosyl-tRNA synthetase PFAM: aminoacyl-tRNA synthetase class Ib YP_001533489.1 -# KEGG: sil:SPO2232 hypothetical protein YP_001533490.1 Swiss-Prot: P23869-Peptidyl-prolyl cis-trans isomerase B PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type YP_001533491.1 Swiss-Prot: P0AFL3-Peptidyl-prolyl cis-trans isomerase A PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; cyclophilin type YP_001533492.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001533493.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis YP_001533494.1 PFAM: Septum formation initiator KEGG: jan:Jann_1692 septum formation initiator; similar to septum formation initiator YP_001533495.1 Swiss-Prot: Q820A6-Pyruvate dehydrogenase E1 component subunit alpha PFAM: dehydrogenase E1 component YP_001533496.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase YP_001533497.1 Swiss-Prot: Q9R9N3-Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001533498.1 Swiss-Prot: P0A9D4-Serine acetyltransferase TIGRFAM: serine O-acetyltransferase PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein YP_001533500.1 KEGG: sil:SPO2250 hypothetical protein YP_001533501.1 TIGRFAM: putative phage cell wall peptidase, NlpC/P60 family PFAM: NLP/P60 protein KEGG: sil:SPO2251 hypothetical protein; similar to phage cell wall peptidase, NlpC/P60 family YP_001533502.1 PFAM: conserved hypothetical protein KEGG: rsq:Rsph17025_1087 hypothetical protein YP_001533503.1 Conserved hypothetical protein TIGR02217, PFAM: conserved hypothetical protein, KEGG: sil:SPO2253 hypothetical protein YP_001533504.1 COG5281, Phage-related minor tail protein [Function unknown].; similar to Phage-related minor tail protein YP_001533505.1 TIGR02216# phage conserved hypothetical protein YP_001533506.1 KEGG: rsq:Rsph17025_1083 hypothetical protein YP_001533507.1 TIGRFAM: phage major tail protein, TP901-1 family KEGG: sit:TM1040_1065 phage major tail protein, TP901-1; similar to Phage major tail protein, TP901-1 YP_001533508.1 KEGG: sil:SPO2258 hypothetical protein YP_001533509.1 TIGR01563# phage head-tail adaptor, putative, SPP1 family; IPR013045 Conserved hypothetical protein 1563; TIGRFAM: phage head-tail adaptor, putative; KEGG: sil:SPO2259 head-tail adaptor, putative YP_001533510.1 KEGG: rde:RD1_3027 hypothetical protein, TIGR02215 phage conserved hypothetical protein, phiE125 gp8 family YP_001533511.1 TIGRFAM: phage major capsid protein, HK97 family PFAM: major capsid protein HK97 KEGG: jan:Jann_1635 phage major capsid protein, HK97; HK97 family YP_001533512.1 TIGRFAM: phage prohead protease, HK97 family PFAM: peptidase U35 phage prohead HK97 KEGG: sil:SPO2262 phage prohead protease, HK97 family; HK97 family YP_001533513.1 KEGG: jan:Jann_1633 hypothetical protein YP_001533514.1 TIGRFAM: phage portal protein, HK97 family PFAM: portal protein KEGG: rde:RD1_3033 phage portal protein, putative; HK97 family YP_001533515.1 PFAM: protein of unknown function DUF264 KEGG: rde:RD1_3034 hypothetical protein YP_001533516.1 PFAM: aminodeoxychorismate lyase KEGG: jan:Jann_1630 aminodeoxychorismate lyase; related to aminodeoxychorismate lyase YP_001533517.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001533518.1 carries the fatty acid chain in fatty acid biosynthesis YP_001533519.1 Swiss-Prot: P0AEK2- 3-oxoacyl-[acyl-carrier-protein] reductase fabG Swiss-Prot: P72332-Nodulation protein G TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR YP_001533520.1 Swiss-Prot hit: spP0AAI9 (FABD_ECOLI); TIGR00128# malonyl CoA-acyl carrier protein transacylase PFAM: Acyl transferase KEGG: rsq:Rsph17025_1221 malonyl CoA-acyl carrier protein transacylase YP_001533521.1 PFAM: YceI family protein; cytochrome B561 KEGG: rde:RD1_3041 cytochrome b561, putative YP_001533522.1 COG2353 - Uncharacterized conserved protein PFAM: YceI family protein; related to YceI family protein YP_001533523.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001533524.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001533525.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001533526.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001533527.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001533528.1 PFAM: ETC complex I subunit conserved region KEGG: sit:TM1040_0143 ETC complex I subunit conserved region YP_001533529.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001533532.1 PFAM: Entericidin EcnAB; similar to Entericidin EcnAB YP_001533534.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001533535.1 PFAM: MOSC domain containing protein (pfam03473) KEGG: sil:SPO0448 MOSC domain protein; similar to MOCO sulphurase (MOSC domain) YP_001533536.1 TIGRFAM: aspartate racemase PFAM: Asp/Glu racemase KEGG: atc:AGR_L_3474 hypothetical protein YP_001533537.1 PFAM: regulatory protein TetR KEGG: gvi:gll0188 TetR family transcriptional regulatory protein YP_001533538.1 KEGG: tbd:Tbd_0484 hypothetical protein PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family (pfam04140) COG2020: Putative protein-S-isoprenylcysteine methyltransferase YP_001533540.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001533543.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine YP_001533544.1 KEGG:sil:SPO0457 hypothetical protein YP_001533545.1 Swiss-Prot: spP39844, spP45161: Penicillin-binding protein 4 TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C KEGG: sit:TM1040_2259 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_001533546.1 Swiss-Prot: spQ9ZE70 COG5006: predicted permease, DMT superfamily PFAM: protein of unknown function DUF6 transmembrane KEGG: jan:Jann_3630 protein of unknown function DUF6, transmembrane; associated with drug/metabolite transport YP_001533547.1 KEGG: sil:SPO0459 hypothetical protein YP_001533548.1 PFAM: protein of unknown function DUF427 KEGG: jan:Jann_3615 protein of unknown function DUF427 YP_001533549.1 PFAM: pyridoxamine 5-phosphate oxidase-related FMN-binding KEGG: jan:Jann_3613 pyridoxamine 5-phosphate oxidase-related, FMN-binding; related to pyridoxamine 5-phosphate oxidase YP_001533550.1 PFAM: UspA domain protein KEGG: rde:RD1_4076 universal stress family protein, putative YP_001533551.1 PFAM: Antibiotic biosynthesis monooxygenase KEGG: sil:SPO0462 antibiotic biosynthesis monooxygenase domain protein; related to antibiotic biosynthesis monooxygenase YP_001533552.1 KEGG: rsq:Rsph17025_2878 hypothetical protein YP_001533553.1 PFAM: pfam00991 ParA family ATPase COG1192: ATPases involved in chromosome partitioning; associated with ATPases involved in chromosome partitioning YP_001533554.1 COG3809: Uncharacterized protein conserved in bacteria KEGG: rde:RD1_1249 hypothetical protein YP_001533555.1 Swiss-Prot entry: P0A1A1 Acyl-CoA thioester hydrolase yciA COG1607: Acyl-CoA hydrolase PFAM: thioesterase superfamily protein KEGG: sil:SPO0440 thioesterase family protein YP_001533556.1 PFAM: Cold-shock protein DNA-binding SMART: Cold shock protein KEGG: rde:RD1_1402 cold shock protein CspA-related protein, putative YP_001533557.1 PFAM: protein of unknown function DUF1332 KEGG: sil:SPO1309 hypothetical protein COG4103: Uncharacterized protein conserved in bacteria YP_001533558.1 COG4598: ABC-type histidine transport system, ATPase component PFAM: ABC transporter related SMART: AAA ATPase KEGG: rde:RD1_1899 amino acid ABC transporter, ATP-binding protein; ATPase subunit YP_001533559.1 PFAM: extracellular solute-binding protein family 3 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain SMART: ionotropic glutamate receptor KEGG: rde:RD1_1898 periplasmic binding protein, putative; family 3 YP_001533560.1 Swiss-Prot entry: P52094 Histidine transport system permease protein hisQ COG4215: ABC-type arginine transport system, permease component KEGG: sit:TM1040_1713 binding-protein-dependent transport systems inner membrane component YP_001533561.1 Swiss-Prot entry: P0A2I7 Histidine transport system permease protein hisM TIGRFAM: polar amino acid ABC transporter, inner membrane subunit PFAM: binding-protein-dependent transport systems inner membrane component KEGG: sit:TM1040_1714 amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; inner membrane subunit YP_001533562.1 PFAM: glutamine amidotransferase class-I KEGG: pde:Pden_1396 glutamine amidotransferase class-I COG0518: GMP synthase - Glutamine amidotransferase domain YP_001533563.1 Swiss-Prot: P78061-Gamma-glutamylputrescine synthetase / Q9HNI2-Glutamine synthetase PFAM: glutamine synthetase catalytic region KEGG: sil:SPO1300 glutamine synthetase family protein YP_001533564.1 Swiss-Prot: P37906-Probable oxidoreductase PFAM: FAD dependent oxidoreductase KEGG: sit:TM1040_1839 FAD dependent oxidoreductase YP_001533565.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II KEGG: sil:SPO1295 aminotransferase, DegT/DnrJ/EryC1/StrS family COG0399:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; DegT/DnrJ/EryC1/StrS family YP_001533566.1 PFAM: regulatory protein LysR; LysR substrate-binding Swiss-Prot: P0ACQ4-contains the same pfam domains KEGG: sil:SPO0980 transcriptional regulator, LysR family; LysR family YP_001533567.1 TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein KEGG: rsq:Rsph17025_0856 polyhydroxyalkonate synthesis repressor, PhaR; PhaR YP_001533568.1 NCBI: YP_001043910 - hypothetical protein Rsph17029_2035 YP_001533569.1 NCBI: YP_682186 - hypothetical protein RD1_1889 YP_001533570.1 Swiss-Prot: P50176 - Poly-beta-hydroxybutyrate polymerase TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I PFAM: Poly-beta-hydroxybutyrate polymerase domain protein KEGG: rsh:Rsph17029_2036 poly(R)-hydroxyalkanoic acid synthase, class I YP_001533571.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular PFAM: PHB de-polymerase domain protein KEGG: sil:SPO1291 polyhydroxyalkanoate depolymerase, intracellular; intracellular YP_001533572.1 COG0620: Methionine synthase II (cobalamin-independent) PFAM: Methionine synthase vitamin-B12 independent KEGG: jan:Jann_1114 methionine synthase, vitamin-B12 independent YP_001533574.1 PFAM: protein of unknown function DUF1486 KEGG: rde:RD1_3943 hypothetical protein YP_001533575.1 Swiss-Prot: P0ACP7-HTH-type transcriptional repressor purR KEGG: rde:RD1_3944 transcriptional regulatory protein, LacI family, putative PFAM: periplasmic binding protein/LacI transcriptional regulator SMART: regulatory protein LacI; LacI family YP_001533576.1 Swiss-Prot: P50199 Gluconate 5-dehydrogenase (SDR family protein) PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein KEGG: jan:Jann_1106 short-chain dehydrogenase/reductase SDR YP_001533578.1 PFAM: protein of unknown function DUF1486 KEGG: rde:RD1_3946 hypothetical protein YP_001533579.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001533580.1 PFAM: alpha/beta hydrolase fold KEGG: rsp:RSP_0384 hypothetical protein YP_001533581.1 PFAM: protein of unknown function DUF1052 KEGG: jan:Jann_3406 protein of unknown function DUF1052 YP_001533582.1 KEGG: rsq:Rsph17025_0423 hypothetical protein YP_001533583.1 COG3335: Transposase and inactivated derivatives PFAM: Integrase core domain; related to transposase and inactivated derivatives YP_001533584.1 COG3415 Transposase and inactivated derivatives; related to transposase and inactivated derivatives YP_001533586.1 Swiss-Prot: Q0APG4-N utilization substance protein B homolog TIGRFAM: transcription antitermination factor NusB PFAM: NusB/RsmB/TIM44 YP_001533587.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001533588.1 Swiss-Prot: P0A7J0 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II YP_001533589.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001533590.1 Swiss-Prot: P42218 - Capsule polysaccharide export protein kpsS PFAM: Capsule polysaccharide biosynthesis protein KEGG: jan:Jann_3418 capsule polysaccharide biosynthesis YP_001533591.1 Swiss-Prot: P0A932 - Putative polysaccharide export protein yccZ [Precursor] PFAM: polysaccharide export protein KEGG: sil:SPO1756 polysaccharide biosynthesis/export protein YP_001533592.1 Swiss-Prot: P42217 - Capsule polysaccharide export protein kpsC PFAM: Capsule polysaccharide biosynthesis protein KEGG: sil:SPO1755 capsular polysaccharide export protein KpsC YP_001533593.1 Swiss-Prot: P25539 - Riboflavin biosynthesis protein ribD (includes: EC:1.1.1.193 - 5-amino-6-(5-phosphoribosylamino)uracil reductase EC:3.5.4.26 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase) TIGRFAM: riboflavin biosynthesis protein RibD YP_001533594.1 Swiss-Prot: Q1GEP8 and P0A8D0 - Transcriptional repressor nrdR PFAM: ATP-cone domain protein KEGG: rsq:Rsph17025_0843 ATP-cone domain protein YP_001533595.1 PFAM: protein of unknown function UPF0047 KEGG: sit:TM1040_2137 protein of unknown function UPF0047 YP_001533598.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001533599.1 synthesizes RNA primers at the replication forks YP_001533600.1 Swiss-Prot: Q46338 - Sarcosine oxidase subunit gamma TIGR01375# sarcosine oxidase, gamma subunit family, heterotetrameric form; gamma subunit YP_001533601.1 TIGRFAM: sarcosine oxidase, alpha subunit family (TIGR01372) Swiss-Prot: O87386 - Sarcosine oxidase subunit alpha PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein barrel; alpha subunit family YP_001533602.1 Swiss-Prot: O87387 - Sarcosine oxidase subunit delta PFAM: Sarcosine oxidase delta subunit heterotetrameric KEGG: sil:SPO1745 sarcosine oxidase, delta subunit family; delta subunit heterotetrameric YP_001533603.1 Swiss-Prot: O87388 - Sarcosine oxidase subunit beta TIGRFAM: sarcosine oxidase, beta subunit family PFAM: FAD dependent oxidoreductase KEGG: jan:Jann_3445 sarcosine oxidase, beta subunit family YP_001533604.1 IPR002035: von Willebrand factor, type A YP_001533605.1 PFAM: TadE family protein KEGG: rsh:Rsph17029_2053 hypothetical protein; associated with TadE-like protein family YP_001533606.1 KEGG: rde:RD1_2616 hypothetical protein YP_001533607.1 KEGG: sil:SPO1739 hypothetical protein YP_001533608.1 PFAM: regulatory protein TetR KEGG: rsq:Rsph17025_0835 transcriptional regulator, TetR family; TetR-related YP_001533610.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001533611.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001533612.1 Swiss-Prot: P21893 - Single-stranded-DNA-specific exonuclease recJ TIGRFAM: single-stranded-DNA-specific exonuclease RecJ PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1 KEGG: sit:TM1040_2166 single-stranded-DNA-specific exonuclease RecJ YP_001533614.1 Swiss-Prot: P12281 - Molybdopterin biosynthesis protein TIGRFAM: molybdenum cofactor synthesis domain PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV YP_001533615.1 Swiss-Prot: Q57366 - Dimethyl sulfoxide reductase [Precursor] PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region KEGG: rde:RD1_3664 dimethyl sulfoxide reductase YP_001533616.1 differing Swiss-Prot hits: P0A9Q1-Aerobic respiration control protein arcA; P0AA16-Transcriptional regulatory protein ompR; P38684-TorCAD operon transcriptional regulatory protein torR; putative arcA, ompR or torR protein YP_001533617.1 differing Swiss-Prot hits: P0AEC3-Aerobic respiration control sensor protein arcB P39453-Sensor protein torS PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein YP_001533618.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001533619.1 PFAM: helix-turn-helix- domain containing protein AraC type COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain KEGG: mva:Mvan_3996 helix-turn-helix-domain containing protein, AraC type; AraC family YP_001533620.1 Swiss-Prot: Q47PU3-Phenylacetone monooxygenase pfam00743: Flavin-binding monooxygenase-like KEGG: rha:RHA1_ro08185 monooxygenase YP_001533621.1 Swiss-Prot: Q11037-Uncharacterized protein Rv1367c/MT1414 PFAM: beta-lactamase COG1680: Beta-lactamase class C and other penicillin binding proteins; related to beta-lactamase YP_001533623.1 COG1846: Transcriptional regulators PFAM: regulatory protein MarR KEGG: reu:Reut_B5322 regulatory protein, MarR; associated with transcriptional regulators, marR family YP_001533624.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit KEGG: rde:RD1_3648 hypothetical protein; 4TM/12TM fusion protein YP_001533625.1 TIGRFAM: TRAP transporter solute receptor, TAXI family KEGG: rde:RD1_3647 TRAP-type transporter, periplasmic component , putative; TAXI family YP_001533626.1 PFAM: amidohydrolase; Amidohydrolase 3 KEGG: slo:Shew_0983 amidohydrolase YP_001533627.1 probably associated with sugar transport; PFAM: Carbohydrate-selective porin OprB KEGG: cps:CPS_0267 hypothetical protein YP_001533628.1 PFAM: protein of unknown function DUF306 Meta and HslJ YP_001533629.1 pfam05976: DUF893 YP_001533630.1 PFAM: secretion protein HlyD family protein KEGG: rde:RD1_3593 multidrug resistance efflux pump, putative; HlyD family YP_001533631.1 PFAM: Pyrrolo-quinoline quinone KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative COG4993: Glucose dehydrogenase YP_001533632.1 PFAM: amidohydrolase; Amidohydrolase 3 COG1228: Imidazolonepropionase and related amidohydrolases KEGG: sus:Acid_5787 amidohydrolase YP_001533633.1 PFAM: transposase IS4 family protein COG3293: Transposase and inactivated derivatives KEGG: pde:Pden_3333 transposase, IS4 family protein YP_001533634.1 COG3293: Transposase and inactivated derivatives KEGG: sit:TM1040_0173 transposase orfA IS5 family element; associated with replication, recombination and repair YP_001533635.1 COG3457: Predicted amino acid racemase PFAM: alanine racemase domain protein, N-terminal domain; no C-terminal domain YP_001533636.1 IPR011669: protein of unknown function DUF1611 YP_001533640.1 PFAM: NnrS family protein COG3213: Uncharacterized protein involved in response to NO KEGG: rde:RD1_1694 NnrS protein, putative; associated with NO response YP_001533641.1 Swiss-Prot: P69506-Regulator of cell morphogenesis and NO signaling COG2846: Regulator of cell morphogenesis and NO signaling PFAM: Hemerythrin HHE cation binding domain protein YP_001533642.1 PFAM: globin KEGG: hne:HNE_1540 protozoan/cyanobacterial globin family protein COG2346: truncated hemoglobins; similar to bacterial-like globin YP_001533643.1 Swiss-Prot: P0AF63-HTH-type transcriptional repressor nsrR TIGR00738: rrf2 family protein (putative transcriptional regulator) PS51197: Rrf2-type HTH domain profile; BadM/Rrf2 family YP_001533646.1 Swiss-Prot: P39138-Arginase TIGRFAM: arginase PFAM: Arginase/agmatinase/formiminoglutamase COG0010: Arginase/agmatinase/formimionoglutamate hydrolase, arginase family KEGG: rde:RD1_1416 arginase YP_001533647.1 catalyzes the formation of L-proline from L-ornithine YP_001533648.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain YP_001533650.1 PROSITE: PS50860-Aminoacyl-transfer RNA synthetases class-II profiles PFAM: Threonyl/alanyl tRNA synthetase SAD KEGG: rsh:Rsph17029_0823 threonyl/alanyl tRNA synthetase, SAD YP_001533651.1 Swiss-Prot: P0ABK5-Cysteine synthase A PFAM: Pyridoxal-5-phosphate-dependent protein beta subunit COG0031: Cysteine synthase IMG Term YP_001533652.1 PFAM: NUDIX hydrolase; AIG2 family protein KEGG: jan:Jann_1992 nucleoside diphosphate pyrophosphatase YP_001533654.1 Swiss-Prot: P0A9H7-Cyclopropane-fatty-acyl-phospholipid synthase PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001533655.1 Swiss-Prot: P00914-deoxyribodipyrimidine photo-lyase phrB PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein YP_001533656.1 Swiss-Prot: P26646-Protein yhdH TIGRFAM: Quinone oxidoreductase putative YhdH/YhfP PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; YhdH YP_001533657.1 DmdA; DMSP demethylase; in Silicibacter knockout of this gene results in an inability to convert DMSP to methanethiol which is restored with a cloned copy of the gene YP_001533658.1 Swiss-Prot: Q02886-Protein dinB PFAM: DinB family protein KEGG: acr:Acry_1562 DinB family protein COG2318: Uncharacterized protein conserved in bacteria; associated with DNA damage-inducible (din) genes YP_001533659.1 PFAM: protein of unknown function DUF1326 KEGG: rde:RD1_2286 hypothetical protein YP_001533661.1 PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: rde:RD1_2283 transcriptional regulator, GntR family, putative; GntR HTH YP_001533662.1 Swiss-Prot: P31133-Putrescine-binding periplasmic protein [Precursor] SSF53850: Periplasmic binding protein-like II superfamily YP_001533665.1 SSF88874: Receptor-binding domain of short tail fibre protein gp12 superfamily PFAM: Tail Collar domain protein YP_001533666.1 PFAM: Tail Collar domain protein YP_001533667.1 PFAM: protein of unknown function DUF1194 KEGG: rsq:Rsph17025_0723 protein of unknown function DUF1194 YP_001533668.1 PFAM: Antibiotic biosynthesis monooxygenase COG2329: Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides KEGG: reu:Reut_B5114 antibiotic biosynthesis monooxygenase; similar to antibiotic biosynthesis monooxygenase YP_001533669.1 Swiss-Prot: Q55027-Probable chromate transport protein TIGRFAM: chromate transporter, chromate ion transporter (CHR) family PFAM: Chromate transporter KEGG: jan:Jann_1226 chromate transporter YP_001533670.1 COG3814: Uncharacterized protein conserved in bacteria PFAM: protein of unknown function DUF1321 KEGG: sit:TM1040_1450 protein of unknown function DUF1321 YP_001533671.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001533672.1 PFAM: Ribbon-helix-helix protein, copG family COG4321:Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis YP_001533673.1 KEGG: jan:Jann_3588 hypothetical protein YP_001533674.1 PFAM: cytochrome P450 KEGG: jan:Jann_2396 cytochrome P450 YP_001533675.1 KEGG: sil:SPO1897 hypothetical protein YP_001533676.1 PFAM: SirA family protein KEGG: sil:SPO1895 SirA family protein Swiss-Prot: Q2NWX1-Sulfurtransferase tusA YP_001533677.1 Swiss-Prot: P21513-Ribonuclease E TIGRFAM: ribonuclease, Rne/Rng family KEGG: sit:TM1040_1459 ribonuclease, Rne/Rng family; Rne/Rng family YP_001533678.1 PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit Swiss-Prot: P44483-Putative TRAP transporter large permease protein HI0050 TIGR00786: TRAP transporter, DctM subunit KEGG: sil:SPO2571 TRAP transporter, DctM subunit, putative; DctM subunit YP_001533679.1 PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component COG4665: TRAP-type mannitol/chloroaromatic compound transport system, small permease component; associated with TRAP transporters, DctQ component YP_001533680.1 PFAM: TRAP dicarboxylate transporter- DctP subunit COG4663: TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component; associated with TRAP dicarboxylate transporter, DctP subunit YP_001533681.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; Cache type 2 domain protein Swiss-Prot: P09835-Sensor protein uhpB; colocated with two component transcriptional regulator YP_001533682.1 PFAM: regulatory protein LuxR; response regulator receiver COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Swiss-Prot: P0AF28-Nitrate/nitrite response regulator protein narL; colocated with histidine kinase; LuxR family YP_001533683.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001533684.1 PFAM: regulatory protein LysR; LysR substrate-binding COG0583: transcriptional regulator Swiss-Prot: P55700-nodulation protein D 2 (Represses the expression of the nodABCIJ-nolO-noeI operon) YP_001533685.1 PFAM: protein of unknown function DUF59 YP_001533686.1 Swiss-Prot: P0AAC8-Iron-binding protein iscA TIGRFAM: iron-sulfur cluster assembly accessory protein PFAM: HesB/YadR/YfhF-family protein YP_001533687.1 Swiss-Prot: Q58296-Putative molybdopterin biosynthesis protein MJ0886 PFAM: molybdopterin binding domain COG0303: Molybdopterin biosynthesis enzyme YP_001533688.1 IPR003777 / pfam02625 XdhC and CoxI family protein COG1975: Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; related to XdhC and CoxI family YP_001533689.1 PFAM: Protein of unknown function DUF1800 COG5267: Uncharacterized protein conserved in bacteria YP_001533690.1 PFAM: protein of unknown function DUF1501 COG4102: Uncharacterized protein conserved in bacteria YP_001533691.1 PFAM: major facilitator superfamily MFS_1 KEGG: reu:Reut_A3422 major facilitator superfamily MFS_1 Swiss-Prot: P77389-Inner membrane transport protein YP_001533692.1 PFAM: VWA containing CoxE family protein KEGG: jan:Jann_1760 VWA containing CoxE-like YP_001533693.1 PFAM: ATPase associated with various cellular activities AAA_5 KEGG: sil:SPO2646 hypothetical protein Swiss-Prot: Q4L6B6-Uncharacterized protein SH1500 YP_001533694.1 COG1960: Acyl-CoA dehydrogenases PFAM: Acyl-CoA dehydrogenase YP_001533695.1 PFAM: Lysine exporter protein (LYSE/YGGA) KEGG: jan:Jann_3206 lysine exporter protein (LysE/YggA) YP_001533697.1 Swiss-Prot: Q03287-Urease accessory protein ureG TIGRFAM: urease accessory protein UreG PFAM: cobalamin synthesis protein P47K KEGG: rsq:Rsph17025_0992 urease accessory protein UreG YP_001533698.1 COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Swiss-Prot: P29911-Uncharacterized 13.8 kDa protein in nqo9-nqo10 intergenic region PFAM: Carboxymuconolactone decarboxylase; related to carboxymuconolactone decarboxylase YP_001533699.1 Swiss-Prot: Q9HUS1-Urease accessory protein ureF PFAM: Urease accessory protein UreF COG0830: Urease accessory protein UreF YP_001533700.1 PFAM: UreE urease accessory domain protein PIRSF036402: urease accessory protein UreE (nickel metallochaperone) Swiss-Prot: Q9AQT2-Urease accessory protein ureE YP_001533702.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001533705.1 Swiss-Prot: Q28RJ8-Urease subunit beta ureB TIGRFAM: urease, beta subunit PFAM: Urease beta subunit YP_001533706.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001533707.1 Swiss-Prot: P42888-Urease accessory protein ureD PFAM: Urease accessory protein UreD KEGG: rsh:Rsph17029_1955 urease accessory protein UreD YP_001533708.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001533709.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001533710.1 unwinds double stranded DNA YP_001533711.1 PFAM: histidine kinase HAMP region domain protein KEGG: rde:RD1_0232 HAMP domain protein, putative YP_001533712.1 PFAM: protein of unknown function DUF1194 KEGG: mes:Meso_1299 protein of unknown function DUF1194 YP_001533714.1 PFAM: protein of unknown function DUF839 KEGG: rde:RD1_0767 hypothetical protein COG3211: Predicted phosphatase YP_001533715.1 Swiss-Prot: Q92R07-Alanine racemase alr TIGRFAM: alanine racemase PFAM: alanine racemase domain protein YP_001533716.1 Swiss-Prot: P64606-UPF0393 inner membrane protein yrbE TIGR00056: conserved hypothetical integral membrane protein PFAM: protein of unknown function DUF140 COG0767: ABC-type transport system involved in resistance to organic solvents, permease component; similar to UPF0393 inner membrane protein yrbE YP_001533717.1 Swiss-Prot: P63386-Uncharacterized ABC transporter ATP-binding protein yrbF COG1127: ABC-type transport system involved in resistance to organic solvents, ATPase component YP_001533718.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001533720.1 Swiss-Prot: P33517- Cytochrome c oxidase subunit 1 ctaD TIGRFAM: Cytochrome c oxidase subunit I type PFAM: cytochrome c oxidase subunit I YP_001533722.1 Swiss-Prot:P0ABS1-DnaK suppressor protein dksA COG1734: DnaK suppressor protein; related to DnaK suppressor protein YP_001533723.1 COG1610: Uncharacterized conserved protein Swiss-Prot: P54464-Uncharacterized protein yqeY YP_001533724.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001533725.1 PFAM: glycosyl transferase family 2 Swiss-Prot: P75905-Biofilm PGA synthesis N-glycosyltransferase pgaC COG1215: Glycosyltransferases, probably involved in cell wall biogenesis; family 2 YP_001533726.1 Swiss-Prot: P76114-Uncharacterized HTH-type transcriptional regulator PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: sil:SPO1375 transcriptional regulator, GntR family; GntR family YP_001533727.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; pyrimidine 5-nucleotidase PFAM: Haloacid dehalogenase domain protein hydrolase KEGG: sil:SPO1374 pyrimidine 5-nucleotidase YP_001533729.1 Swiss-Prot: P75728-2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase, ubiF TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase KEGG: sil:SPO1371 2-octaprenyl-6-methoxyphenol hydroxylase, putative; ubiF YP_001533730.1 PFAM: Aminotransferase class-V KEGG: rde:RD1_1957 aminotransferase family protein, putative COG0075: Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; class 5 YP_001533731.1 PFAM: regulatory protein AsnC/Lrp family; regulatory protein ArsR KEGG: sil:SPO1368 transcriptional regulator, AsnC family COG1522: Transcriptional regulators; AsnC family YP_001533732.1 Swiss-Prot: P0ACJ5-Uncharacterized HTH-type transcriptional regulator ybaO PFAM: regulatory protein AsnC/Lrp family KEGG: sil:SPO1367 transcriptional regulator, AsnC family; AsnC family YP_001533733.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001533734.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001533735.1 Swiss-Prot: P0AC13-Dihydropteroate synthase folP TIGRFAM: dihydropteroate synthase PFAM: dihydropteroate synthase DHPS YP_001533736.1 Swiss-Prot: Q9X8I0-Dihydroneopterin aldolase folB PFAM: dihydroneopterin aldolase TIGR00525: dihydroneopterin aldolase TIGR00526: FolB domain YP_001533737.1 PFAM: cell wall hydrolase SleB KEGG: sit:TM1040_2308 cell wall hydrolase, SleB COG3773: Cell wall hydrolyses involved in spore germination; related to cell wall hydrolase YP_001533738.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001533739.1 Swiss-Prot: Q986B5-Glycyl-tRNA synthetase beta chain glyS TIGRFAM: glycyl-tRNA synthetase, beta subunit YP_001533741.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001533742.1 Swiss-Prot: P55377-Uncharacterized protein y4bJ YP_001533743.1 Swiss-Prot: P23849-Trk system potassium uptake protein trkG PFAM: cation transporter KEGG: rde:RD1_1942 trk system potassium uptake protein COG0168: Trk-type K+ transport systems, membrane components YP_001533744.1 Swiss-Prot: P77526-Uncharacterized GST-like protein PFAM: Glutathione S-transferase domain KEGG: rde:RD1_1937 glutathione S-transferase, putative YP_001533745.1 Swiss-Prot: P55218-O-succinylhomoserine sulfhydrylase P00935-Cystathionine gamma-synthase TIGRFAM: O-succinylhomoserine sulfhydrylase PFAM: Cys/Met metabolism PLP-dependent enzyme YP_001533746.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_001533747.1 Swiss-Prot: Q8XTT4-Putative chloride channel protein clcB-like / P76175-Voltage-gated ClC-type chloride channel, clcB PFAM: Chloride channel core KEGG: jan:Jann_2746 Cl-channel, voltage gated; clcB-like YP_001533748.1 Swiss-Prot: P05824-DNA repair protein recN TIGRFAM: DNA repair protein RecN PFAM: SMC domain protein KEGG: sil:SPO1207 DNA repair protein RecN YP_001533749.1 Swiss-Prot: P0AC02-UPF0169 lipoprotein yfiO [Precursor] YP_001533750.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001533751.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001533752.1 Swiss-Prot: P0ABH0-Cell division protein ftsA TIGR01174: cell division protein FtsA; colocated with ftsZ and ftsQ YP_001533753.1 Swiss-Prot: Q9X5H9-Cell division protein ftsQ homolog PFAM: cell division protein FtsQ KEGG: sil:SPO1202 cell division protein FtsQ COG1589: Cell division septal protein; colocated with ftsZ and ftsA YP_001533754.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001533755.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001533757.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001533758.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001533759.1 Swiss-Prot: P0ABG4-Cell division protein ftsW TIGRFAM: cell division protein FtsW PFAM: cell cycle protein; colocated with ftsA,ftsZ and (putative)ftsQ YP_001533760.1 PFAM: Hemolysin-type calcium-binding region YP_001533761.1 PFAM: peptidase S8 / subtilase family KEGG: rde:RD1_4002 subtilisin carlsberg precursor, putative PTHR10795: subtilisin-related serine protease; related to subtilase YP_001533762.1 KEGG: rde:RD1_4000 hypothetical protein YP_001533763.1 Swiss-Prot: P0AGB6-RNA polymerase sigma-E factor rpoE TIGRFAM: RNA polymerase sigma-70 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; sigma-24 subunit, ECF subfamily YP_001533764.1 Swiss-Prot: P11553- L-fuculokinase fucK PFAM: carbohydrate kinase FGGY KEGG: rde:RD1_3075 carbohydrate kinases, putative COG1070: Sugar (pentulose and hexulose) kinases; FGGY family YP_001533765.1 TIGRFAM: L-rhamnose 1-epimerase PFAM: protein of unknown function DUF718 KEGG: jan:Jann_2598 protein of unknown function DUF718 YP_001533766.1 Swiss-Prot: P0AE26- L-arabinose transport system permease protein araH PFAM: inner-membrane translocator KEGG: jan:Jann_2597 inner-membrane translocator YP_001533767.1 Swiss-Prot: P77672-Inner membrane ABC transporter permease protein ydeY PFAM: inner-membrane translocator KEGG: rde:RD1_3078 ribose ABC transporter, permease protein YP_001533768.1 Swiss-Prot: P04983-Ribose import ATP-binding protein rbsA COG1129: ABC-type sugar transport system, ATPase component PFAM: ABC transporter related SMART: AAA ATPase YP_001533769.1 TIGRFAM: rhamnose ABC transporter, periplasmic rhamnose-binding protein KEGG: rde:RD1_3080 sugar ABC transporter, ATP binding protein, putative COG1879: ABC-type sugar transport system, periplasmic component YP_001533770.1 Swiss-Prot: P0A9W0-HTH-type transcriptional regulator PFAM: regulatory protein DeoR KEGG: jan:Jann_2593 transcriptional regulator, DeoR family COG1349: Transcriptional regulators of sugar metabolism; colocated with sugar transport system; DeoR family YP_001533771.1 Swiss-Prot: P40747-Uncharacterized oxidoreductase yuxG TIGRFAM: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein KEGG: jan:Jann_2592 short-chain dehydrogenase/reductase SDR COG3347: Uncharacterized conserved protein YP_001533772.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_001533773.1 PFAM: amidohydrolase 2 KEGG: pau:PA14_36110 putative hydrolase COG3618: Predicted metal-dependent hydrolase of the TIM-barrel fold YP_001533774.1 PFAM: protein of unknown function DUF112 transmembrane COG3333: Uncharacterized protein conserved in bacteria YP_001533776.1 Swiss-Prot: P0A177-UPF0065 protein in clcB-clcD intergenic region [Precursor] PFAM: Bordetella uptake gene (bug) product COG3181: Uncharacterized protein conserved in bacteria; similar to UPF0065 protein YP_001533777.1 Swiss-Prot: Q56694-NADP-dependent fatty aldehyde dehydrogenase aldH PFAM: aldehyde dehydrogenase KEGG: pde:Pden_4865 aldehyde dehydrogenase YP_001533778.1 PTHR22981: 3-hydroxyisobutyrate dehydrogenase-related COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases KEGG: sil:SPO2416 3-hydroxyisobutyrate dehydrogenase family protein; no well-defined Swiss-Prot hits: P0ABQ2, P28811, O34948 YP_001533779.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001533780.1 PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: sil:SPO2434 transcriptional regulator, GntR family COG1802: Transcriptional regulators; GntR family YP_001533781.1 PFAM: dihydrodipicolinate synthetase Swiss-Prot: O69782-Dihydrodipicolinate synthase KEGG: sil:SPOA0244 dihydrodipicolinate synthase family protein YP_001533782.1 PFAM: Mandelate racemase/muconate lactonizing protein PTHR13794: enolase superfamily, mandelate racemase YP_001533783.1 PFAM: protein of unknown function DUF112 transmembrane KEGG: jan:Jann_1159 protein of unknown function DUF112, transmembrane COG3333: Uncharacterized protein conserved in bacteria YP_001533785.1 PFAM: conserved hypothetical protein KEGG: ecp:ECP_4043 hypothetical protein; similar to UPF0065 protein YP_001533786.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001533787.1 PFAM: glycoside hydrolase family 25 KEGG: nha:Nham_3711 glycoside hydrolase, family 25 COG3757: Lyzozyme M1 (1,4-beta-N-acetylmuramidase); associated with glycoside hydrolase YP_001533790.1 PFAM: AAA ATPase central domain protein SMART: AAA ATPase KEGG: ppd:Ppro_0362 AAA ATPase, central domain protein; AAA family YP_001533794.1 KEGG: ppd:Ppro_0366 hypothetical protein YP_001533795.1 PFAM: GPW/gp25 family protein KEGG: ppd:Ppro_0367 gpW/GP25 family protein COG3628: Phage baseplate assembly protein W; related to gene 25-like lysozyme YP_001533796.1 PFAM: PAAR repeat-containing protein KEGG: sdn:Sden_3002 PaaR COG4104: Uncharacterized conserved protein YP_001533797.1 PFAM: Rhs element Vgr protein KEGG: ppd:Ppro_0369 rhs element Vgr protein TIGR01646: Rhs element Vgr protein; related to phage late control gene D YP_001533799.1 TIGRFAM: conserved hypothetical phage tail protein (TIGR02241) PFAM: conserved hypothetical protein KEGG: rde:RD1_4219 hypothetical protein; phage tail region protein YP_001533800.1 TIGRFAM: conserved hypothetical phage tail protein (TIGR02241) PFAM: conserved hypothetical protein KEGG: ppd:Ppro_0372 conserved hypothetical phage tail protein; phage tail region protein YP_001533801.1 PFAM:Phage tail sheath protein KEGG: sdn:Sden_3007 hypothetical protein; related to phage tail sheath protein YP_001533804.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001533805.1 Swiss-Prot: P11880- UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase murF TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein YP_001533806.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001533807.1 Swiss-Prot: P0AD68-Peptidoglycan synthetase ftsI [Precursor] PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain COG0768: Cell division protein FtsI/penicillin-binding protein 2 YP_001533809.1 Swiss-Prot: P60390- S-adenosyl-L-methionine-dependent methyltransferase mraW TIGRFAM: S-adenosyl-methyltransferase MraW PFAM: methyltransferase KEGG: rsq:Rsph17025_0683 S-adenosyl-methyltransferase MraW YP_001533810.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001533811.1 Swiss-Prot: P0AF08-Protein mrp COG0489: ATPases involved in chromosome partitioning; related to protein mrp YP_001533812.1 Swiss-Prot: P0ACJ0- Leucine-responsive regulatory protein PFAM: regulatory protein AsnC/Lrp family KEGG: sil:SPO3612 transcriptional regulator, AsnC family YP_001533813.1 Swiss-Prot: P38101-Inner membrane protein yfiK PFAM: Lysine exporter protein (LYSE/YGGA) KEGG: sil:SPO3613 transporter, LysE family; similar to inner membrane protein yfiK YP_001533814.1 Swiss-Prot:P30864-Uncharacterized HTH-type transcriptional regulator yafC PFAM: regulatory protein LysR; LysR substrate-binding; LysR family YP_001533815.1 PFAM: short-chain dehydrogenase/reductase SDR COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_001533817.1 TIGRFAM / PFAM: Ethyl tert-butyl ether degradation EthD; similar to EthD protein YP_001533818.1 Swiss-Prot: P03018-DNA helicase II PFAM: UvrD/REP helicase KEGG: jan:Jann_2777 UvrD/REP helicase YP_001533819.1 Swiss-Prot: P33232- L-lactate dehydrogenase [cytochrome] lldD PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase KEGG: sit:TM1040_2026 L-lactate dehydrogenase (cytochrome) YP_001533820.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_001533821.1 PFAM: Protein of unknown function DUF1826 KEGG: rde:RD1_1857 hypothetical protein YP_001533822.1 Swiss-Prot: P31521- 47 kDa protein; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein YP_001533823.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955 KEGG: rde:RD1_2203 transcriptional regulator, putative; associated with regulation of transcription YP_001533824.1 Swiss-Prot: O08374- Serine--glyoxylate aminotransferase (Inferred from homology) PFAM: aminotransferase class V KEGG: sme:SMa2139 probable SgaA serine-glyoxylate aminotransferase (SgaT) YP_001533825.1 Swiss-Prot: P0A9I1-Citrate lyase subunit beta PIRSF015582: citrate lyase, beta subunit [Validated]; subunit beta YP_001533826.1 catalyzes the formation of malyl-CoA from malate and CoA YP_001533827.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001533828.1 KEGG: pde:Pden_4111 hypothetical protein YP_001533829.1 IPR003673: CoA-transferase family III KEGG: rrs:RoseRS_4174 acyl-CoA transferase/carnitine dehydratase-like protei YP_001533830.1 Swiss-Prot: P75925-Cytochrome b561 homolog 2 PFAM: cytochrome B561 YP_001533831.1 PFAM: EF hand IPR002048: Calcium-binding EF-hand KEGG: rsh:Rsph17029_2073 putative signal transduction protein with EFhand domain; associated with signal transduction YP_001533832.1 Swiss-Prot: P0AA16-Transcriptional regulatory protein (ompR) PFAM: response regulator receiver; transcriptional regulator domain protein KEGG: rpe:RPE_4561 two component transcriptional regulator, winged helix family; colocated with histidin kinase; winged helix family YP_001533833.1 Swiss-Prot: P0AEJ4-Osmolarity sensor protein (envZ) PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein KEGG: sil:SPOA0358 sensor histidine kinase; colocated with response regulator YP_001533834.1 Swiss-Prot: P0A0V3-Outer membrane protein class 4 [Precursor] PFAM: OmpA/MotB domain protein KEGG: rde:RD1_1126 OmpA family domain protein COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins; related to outer membrane protein (ompA) YP_001533835.1 Swiss-Prot: P18770-Cyclolysin secretion/processing ATP-binding protein cyaB; P26760-Toxin RTX-I translocation ATP-binding protein PFAM: ABC transporter transmembrane region; ABC transporter related SMART: AAA ATPase KEGG: rde:RD1_1124 toxin secretion ABC transporter, ATP-binding component, putative; colocated with secretion protein (HylD family); associated with toxin excretion YP_001533836.1 Swiss-Prot: Q03025-Alkaline protease secretion protein aprE TIGRFAM: type I secretion membrane fusion protein, HlyD family PFAM: secretion protein HlyD family protein KEGG: rde:RD1_1123 HlyD family secretion protein, putative; colocated with ABC transporter; HlyD family YP_001533838.1 KEGG: jan:Jann_0233 hypothetical protein YP_001533841.1 Swiss-Prot: P17985-Insertion element ISR1 uncharacterized 10 kDa protein A3 IPR002514: Transposase IS3/IS911 PFAM: transposase IS3/IS911 family protein KEGG: rde:RD1_3450 inverted repeat region YP_001533842.1 Swiss-Prot: P25438-Insertion element IS476 uncharacterized 39.2 kDa protein PFAM: Integrase catalytic region KEGG: rde:RD1_3449 integrase, catalytic domain, putativ; catalytic region YP_001533843.1 Swiss-Prot: P25438-Insertion element IS476 uncharacterized 39.2 kDa protein PFAM: Integrase catalytic region KEGG: bbt:BBta_7691 integrase, catalytic domain; catalytic region YP_001533844.1 Swiss-Prot: P17985-Insertion element ISR1 uncharacterized 10 kDa protein A3 PFAM: transposase IS3/IS911 family protein KEGG: mag:amb0646 insertion element ISR1 hypothetical 10 kDa protein A3 YP_001533846.1 Swiss-Prot: Q87L85- tRNA-dihydrouridine synthase A PIRSF006621-tRNA-dihydrouridine synthase TIGRFAM: TIM-barrel protein, yjbN family PFAM: dihydrouridine synthase DuS YP_001533847.1 KEGG: sil:SPO1770 hypothetical protein YP_001533848.1 KEGG: sil:SPO1769 hypothetical protein YP_001533849.1 Swiss-Prot: P0AFR2-Putative sulfate transporter ychM TIGRFAM: sulfate transporter PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter KEGG: sit:TM1040_3648 sulfate permease YP_001533851.1 Swiss-Prot: Q8UAA9-Beta-lactamase hydrolase-like protein PFAM: beta-lactamase domain protein KEGG: rde:RD1_0785 metallo-beta-lactamase family protein; related to beta-lactamase hydrolase-like protein YP_001533852.1 Swiss-Prot: Q87AD3-UPF0394 membrane protein PD_1893 PFAM: protein of unknown function DUF395 YeeE/YedE KEGG: sit:TM1040_3646 protein of unknown function DUF395, YeeE/YedE YP_001533853.1 PFAM: protein of unknown function DUF395 YeeE/YedE KEGG: jan:Jann_2818 protein of unknown function DUF395, YeeE/YedE YP_001533854.1 KEGG: rde:RD1_0788 hypothetical protein YP_001533855.1 Swiss-Prot: P0ACJ8-Catabolite gene activator crp PFAM: cyclic nucleotide-binding SMART: regulatory protein Crp KEGG: sil:SPO1615 cyclic nucleotide-binding protein; Crp/Fnr family YP_001533856.1 Swiss-Prot: Q8PYP6-Probable peroxiredoxin PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001533857.1 Swiss-Prot: P0ACQ4-Hydrogen peroxide-inducible genes activator oxyR PFAM: regulatory protein LysR; LysR substrate-binding KEGG: rpb:RPB_4602 transcriptional regulator, LysR family YP_001533858.1 TIGR00816: C4-dicarboxylate transporter/malic acid transport protein PFAM: C4-dicarboxylate transporter/malic acid transport protein KEGG: jan:Jann_2959 C4-dicarboxylate transporter/malic acid transport protein Swiss-Prot: P25396-Tellurite resistance protein tehA YP_001533859.1 KEGG: sil:SPO1613 hypothetical protein YP_001533860.1 PTHR10632: Sulfide quinone-reductase PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001533862.1 PFAM: Bacterial regulatory proteins, crp family KEGG: rru:Rru_A1245 transcriptional regulator, Crp/Fnr family; Crp/Fnr family YP_001533863.1 KEGG: sil:SPO1611 hypothetical protein YP_001533868.1 PFAM: Integral membrane protein DUF112 COG3333: Uncharacterized protein conserved in bacteria YP_001533871.1 Swiss-Prot: Q59727- 4,5-dihydroxyphthalate decarboxylase [predicted] YP_001533872.1 Swiss-Prot: P76004-Uncharacterized protein ycgM PFAM: fumarylacetoacetate (FAA) hydrolase KEGG: rsh:Rsph17029_0213 fumarylacetoacetate (FAA) hydrolase; related to fumarylacetoacetate (FAA) hydrolase YP_001533873.1 Swiss-Prot: P39161-Uxu operon transcriptional regulator PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: ent:Ent638_0750 GntR domain protein; gntR family YP_001533875.1 Swiss-Prot: P0ACL7- Putative L-lactate dehydrogenase operon regulatory protein PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: rle:RL4574 putative GntR family transcriptional regulator; gntR family YP_001533876.1 Swiss-Prot: P76004-Uncharacterized protein ycgM PFAM: fumarylacetoacetate (FAA) hydrolase KEGG: bxe:Bxe_A3618 putative hydrolase; related to fumarylacetoacetate (FAA) hydrolase YP_001533877.1 Swiss-Prot: P40400-Putative aliphatic sulfonates-binding protein [Precursor] PFAM: NMT1/THI5 like domain protein YP_001533878.1 Swiss-Prot: Q57855-Uncharacterized ABC transporter ATP-binding protein MJ0412 PFAM: ABC transporter related SMART: AAA ATPase KEGG: rsh:Rsph17029_3905 ABC transporter related; ATP-binding protein YP_001533879.1 Swiss-Prot: P40401-Putative aliphatic sulfonates transport permease protein PFAM: binding-protein-dependent transport systems inner membrane component; inner membrane component YP_001533880.1 Swiss-Prot: O34736-Uncharacterized oxidoreductase yjmC PFAM: Malate/L-lactate dehydrogenase KEGG: tth:TT_P0035 dehydrogenase YP_001533882.1 COG5412: Phage-related protein YP_001533883.1 PFAM: cell surface receptor IPT/TIG domain protein KEGG: rrs:RoseRS_1653 hypothetical protein YP_001533884.1 PFAM: impB/mucB/samB family SSF50969: quinoprotein amine dehydrogenase, beta chain-like KEGG: gme:Gmet_1144 hypothetical protein YP_001533885.1 KEGG: gme:Gmet_1142 hypothetical protein YP_001533886.1 TIGR02243: conserved hypothetical protein, phage tail-like region KEGG: aeh:Mlg_1745 hypothetical protein YP_001533888.1 PFAM: Gene 25-like lysozyme KEGG: aeh:Mlg_1747 hypothetical protein; related to gene 25-like lysozyme YP_001533889.1 PFAM: Protein of unknown function, DUF586 COG3501: Uncharacterized protein conserved in bacteria YP_001533890.1 PFAM: Phage late control gene D protein KEGG: gme:Gmet_1137 hypothetical protein COG3500: Phage protein D YP_001533893.1 Swiss-Prot: P55530-Uncharacterized AAA family ATPase y4kL PFAM: AAA ATPase central domain protein SMART: AAA ATPase KEGG: gme:Gmet_1133 AAA ATPase, central region; central domain protein YP_001533894.1 ## YP_001533897.1 TIGRFAM: conserved hypothetical phage tail protein PFAM: conserved hypothetical protein KEGG: aeh:Mlg_1757 conserved hypothetical phage tail protein; phage tail region YP_001533898.1 PFAM: tail sheath protein KEGG: gme:Gmet_1128 phage tail sheath protein; related to phage tail sheath protein YP_001533899.1 Swiss-Prot: O32197-Sensory transduction protein PFAM: regulatory protein LuxR; response regulator receiver KEGG: sen:SACE_5003 two component transcriptional regulator, LuxR family; colocated with histidine kinase YP_001533900.1 PFAM: dehydrogenase E1 component; Transketolase central region; Transketolase domain protein; transketolase / dehydrogenase YP_001533901.1 Swiss-Prot: P26489-Sensor protein fixL TIGRFAM: PAS sensor protein PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Cache domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein SMART: PAS domain containing protein, colocated with response regulator YP_001533902.1 Swiss-Prot: P10958-Transcriptional regulatory protein fixJ PFAM: regulatory protein LuxR; response regulator receiver KEGG: rde:RD1_3086 transcriptional regulatory protein FixJ, putative; colocated with histidine kinase YP_001533903.1 Swiss-Prot: P75747-Protein abrB (multi-pass membrane protein / probably involved in gene regulation) PFAM: putative ammonia monooxygenase KEGG: rde:RD1_2159 hypothetical protein; similar to Protein abrB YP_001533904.1 Swiss-Prot: P76114-Uncharacterized HTH-type transcriptional regulator yncC PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: bja:bll2319 transcriptional regulatory protein; GntR family YP_001533905.1 Swiss-Prot: P63177- 23S rRNA (guanosine-2-O-)-methyltransferase rlmB TIGRFAM: RNA methyltransferase, TrmH family, group 3 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding KEGG: rsp:RSP_2239 tRNA/rRNA metyltransferase; TrmH family, group 3 YP_001533906.1 KEGG: jan:Jann_2800 hypothetical protein YP_001533907.1 KEGG: rde:RD1_2147 hypothetical protein YP_001533908.1 PFAM: CoA-binding domain protein KEGG: sil:SPO1153 CoA-binding domain protein YP_001533909.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001533910.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001533911.1 PFAM: putative RNA methylase KEGG: pde:Pden_2378 putative RNA methylase YP_001533912.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001533913.1 COG4731: Uncharacterized protein conserved in bacteria YP_001533914.1 Swiss-Prot: P37024- ATP-dependent RNA helicase hrpB TIGRFAM: ATP-dependent helicase HrpB PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent domain protein SMART: DEAD-like helicases YP_001533916.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001533917.1 required for 70S ribosome assembly YP_001533918.1 KEGG: rsq:Rsph17025_3115 hypothetical protein YP_001533919.1 PFAM: protein of unknown function DUF461 KEGG: rde:RD1_1682 hypothetical protein COG2847: Uncharacterized protein conserved in bacteria YP_001533920.1 PFAM: HpcH/HpaI aldolase KEGG: jan:Jann_2691 HpcH/HpaI aldolase YP_001533921.1 PFAM: Metallo-beta-lactamase superfamily COG1236: Predicted exonuclease of the beta-lactamase fold involved in RNA processing; related to beta-lactamases YP_001533922.1 PFAM: Alpha/beta hydrolase fold-3 domain protein COG0657: Esterase/lipase YP_001533923.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA YP_001533924.1 PFAM: integrase family protein KEGG: rsh:Rsph17029_2267 phage integrase family protein; related to phage integrase YP_001533925.1 TIGRFAM: putative transcriptional regulator, Rrf2 family PFAM: protein of unknown function UPF0074 KEGG: rde:RD1_1855 transcriptional regulator, rrf2 family, putative YP_001533926.1 Swiss-Prot: P31521- 47 kDa protein; PFAM: cobalamin synthesis protein P47K COG0523: Putative GTPases (G3E family) YP_001533927.1 PFAM: Protein of unknown function DUF1826 KEGG: rde:RD1_1857 hypothetical protein YP_001533929.1 PFAM: extracellular solute-binding protein family Swiss-Prot: P76128-Putative ABC transporter periplasmic-binding protein yddS [Precursor] YP_001533930.1 PFAM: ABC transporter related SMART: AAA ATPase Swiss-Prot: P33593-Nickel import ATP-binding protein nikD COG0444:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; ATPase component YP_001533931.1 PFAM: ABC transporter related SMART: AAA ATPase Swiss-Prot: P77622-Uncharacterized ABC transporter ATP-binding protein yddO COG1124: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; ATPase component YP_001533932.1 PFAM: binding-protein-dependent transport systems inner membrane component Swiss-Prot: P75798-Glutathione transport system permease protein gsiC COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_001533933.1 PFAM: binding-protein-dependent transport systems inner membrane component Swiss-Prot: P0AFA9-Nickel transport system permease protein nikC COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_001533934.1 PFAM: protein of unknown function DUF6 transmembrane KEGG: rde:RD1_1864 integral membrane protein, putative YP_001533935.1 PFAM: helix-turn-helix- domain containing protein AraC type KEGG: rde:RD1_0249 transcriptional regulator, AraC family, putative YP_001533936.1 Swiss-Prot: Q06319-Acyl-CoA dehydrogenase, short-chain specific PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain KEGG: rde:RD1_0250 acyl-CoA dehydrogenase, putative YP_001533937.1 Swiss-Prot: O31605-Oligoendopeptidase F homolog TIGRFAM: oligoendopeptidase, pepF/M3 family PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F; pepF/M3 family YP_001533938.1 Swiss-Prot: P64590-Inner membrane protein yhaH PFAM: protein of unknown function DUF805; similar to inner membrane protein yhaH YP_001533940.1 SMART: zinc finger CDGSH-type domain protein KEGG: rde:RD1_1658 hypothetical protein YP_001533941.1 KEGG: sil:SPO0456 hypothetical protein YP_001533942.1 Swiss-Prot: P49305-Putative oxidoreductase ORF334 / Q07982-Glucose--fructose oxidoreductase [Precursor] PFAM: oxidoreductase domain protein; Oxidoreductase domain KEGG: sit:TM1040_0565 oxidoreductase-like YP_001533943.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001533944.1 Swiss-Prot: P33643-Ribosomal large subunit pseudouridine synthase D TIGR00005: pseudouridine synthase, RluA family YP_001533946.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001533947.1 Swiss-Prot: O35016-Low molecular weight protein-tyrosine-phosphatase PFAM: low molecular weight phosphotyrosine protein phosphatase KEGG: sil:SPO0979 low molecular weight phosphotyrosine protein phosphatase YP_001533948.1 KEGG: sit:TM1040_0677 hypothetical protein YP_001533949.1 Swiss-Prot: P0AFN6-Inner membrane transport permease yadH PFAM: ABC-2 type transporter KEGG: sil:SPO0957 ABC transporter, permease protein COG1682 : ABC-type polysaccharide/polyol phosphate export systems, permease component; permease component YP_001533950.1 PFAM: GcrA cell cycle regulator KEGG: jan:Jann_1020 GcrA cell cycle regulator YP_001533951.1 KEGG: sde:Sde_2877 hypothetical protein YP_001533952.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001533953.1 Swiss-Prot: P69488-Divalent-cation tolerance protein cutA PFAM: CutA1 divalent ion tolerance protein YP_001533954.1 KEGG: rde:RD1_3491 hypothetical protein YP_001533955.1 KEGG: sil:SPO0942 hypothetical protein YP_001533956.1 KEGG: sil:SPO0941 hypothetical protein YP_001533957.1 PFAM: peptidase M48 Ste24p KEGG: rde:RD1_1656 peptidase, M48 family, putative; Ste24p YP_001533958.1 KEGG: rde:RD1_1657 hypothetical protein YP_001533959.1 KEGG: sil:SPO0938 hypothetical protein YP_001533960.1 Swiss-Prot: P55682-Uncharacterized transporter y4wD PFAM: major facilitator superfamily MFS_1 YP_001533961.1 Swiss-Prot: P0ACY1-Protein ydjA PFAM: nitroreductase KEGG: rsq:Rsph17025_0371 nitroreductase; related to nitroreductase YP_001533962.1 PFAM: Protein of unknown function (DUF540) YP_001533963.1 PFAM: protein of unknown function DUF1467 KEGG: sil:SPO0933 hypothetical protein YP_001533964.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase Swiss-Prot: P54540-Uncharacterized protein yqjC YP_001533965.1 PFAM: response regulator receiver KEGG: rde:RD1_1178 response regulator, putative YP_001533967.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001533969.1 PFAM: pentapeptide repeat protein YP_001533970.1 Swiss-Prot: Q9Z5D7-Bacteriochlorophyll synthase 23 kDa chain (4-vinyl reductase) TIGRFAM: bacteriochlorophyll 4-vinyl reductase PFAM: 4-vinyl reductase 4VR YP_001533971.1 Swiss-Prot: Q7X2C7-Anaerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase (bchE) TIGRFAM: magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein SMART: Elongator protein 3/MiaB/NifB YP_001533973.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001533975.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001533977.1 Swiss-Prot: P36234-Glycerate dehydrogenase YP_001533978.1 Swiss-Prot: P37584-Protein csaA TIGRFAM: export-related chaperone CsaA PFAM: t-RNA-binding domain protein YP_001533979.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001533980.1 PFAM: Protein of unknown function DUF1790 COG5465: Uncharacterized conserved protein YP_001533982.1 PFAM: protein of unknown function DUF526 COG2960: Uncharacterized protein conserved in bacteria YP_001533983.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001533984.1 PFAM: protein of unknown function DUF185 COG1565: Uncharacterized conserved protein YP_001533985.1 PFAM: protein of unknown function DUF152 TIGR00726: conserved hypothetical protein TIGR00726 YP_001533986.1 KEGG: sil:SPO0905 hypothetical protein YP_001533987.1 Swiss-Prot: P0ACJ0-Leucine-responsive regulatory protein PFAM: regulatory protein AsnC/Lrp family KEGG: rsq:Rsph17025_0257 putative transcriptional regulator, AsnC family YP_001533988.1 Swiss-Prot: P0A9P4-Thioredoxin reductase TIGRFAM: thioredoxin reductase PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A YP_001533989.1 Swiss-Prot: P14532-Cytochrome c551 peroxidase [Precursor] PFAM: Di-haem cytochrome c peroxidase KEGG: sil:SPO0330 cytochrome c peroxidase COG1858: Cytochrome c peroxidase YP_001533990.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from Escherichia coli involved in cysteine biosynthesis YP_001533992.1 Swiss-Prot: P19920-Carbon monoxide dehydrogenase medium chain coxM; PFAM: molybdopterin dehydrogenase FAD-binding COG1319: Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; medium chain YP_001533993.1 Swiss-Prot: P19919-Carbon monoxide dehydrogenase large chain coxL TIGR02416: carbon-monoxide dehydrogenase, large subunit PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs YP_001533994.1 Swiss-Prot: P19921-Carbon monoxide dehydrogenase small chain coxS PFAM: ferredoxin; [2Fe-2S]-binding domain protein COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; small chain YP_001533995.1 PFAM: carbon monoxide dehydrogenase subunit G COG3427: Uncharacterized conserved protein; subunit G YP_001533996.1 PFAM: Bacterial extracellular solute-binding proteins, family 3 SMART: extracellular solute-binding protein family; similar to extracellular solute-binding protein (family 3) YP_001533997.1 PS51007: CYTC SSF46626: Cytochrome_c KEGG: sil:SPO1515 cytochrome c550, putative; related to cytochrome c YP_001533998.1 KEGG: sil:SPO1514 hypothetical protein YP_001533999.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein KEGG: sil:SPO1513 hypothetical protein YP_001534001.1 Swiss-Prot: P0A9U1-Uncharacterized ABC transporter ATP-binding protein ybhF PFAM: ABC transporter related SMART: AAA ATPase; ATP-binding protein YP_001534002.1 PFAM: ABC-2 type transporter Swiss-Prot: P0AFP9-Inner membrane transport permease ybhR KEGG: sil:SPO1510 efflux ABC transporter, permease protein; permease component YP_001534004.1 PFAM: ABC transporter related SMART: AAA ATPase Swiss-Prot: Q47538-Taurine import ATP-binding protein tauB / P0AAI1-Aliphatic sulfonates import ATP-binding protein ssuB; COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; ATP-binding protein YP_001534005.1 SSF53850: Periplasmic binding protein-like II COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; similar to periplasmic binding protein YP_001534006.1 PFAM: cytochrome c class I KEGG: sil:SPO1509 cytochrome c family protein; cytochrome c class I YP_001534007.1 Swiss-Prot: Q9Z4J7-Quinoprotein ethanol dehydrogenase [Precursor] PFAM: Pyrrolo-quinoline quinone SSF50998: Quinonprotein alcohol dehydrogenase-like KEGG: sil:SPO1508 quinoprotein ethanol dehydrogenase YP_001534008.1 PFAM: regulatory protein LuxR; response regulator receiver KEGG: rsp:RSP_2882 two component transcriptional regulator, LuxR family Swiss-Prot: P0AF28-Nitrate/nitrite response regulator protein narL; LuxR family YP_001534009.1 PFAM: domain of unknown function DUF1745 COG3287- Uncharacterized conserved protein YP_001534010.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein YP_001534011.1 PFAM: lipolytic protein G-D-S-L family; G-D-S-L family YP_001534012.1 Swiss-Prot: P0A9T8-Uncharacterized ABC transporter ATP-binding protein ybbA PFAM: ABC transporter related SMART: AAA ATPase; ATP-binding protein YP_001534013.1 PFAM: protein of unknown function DUF214 COG3127: Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Swiss-Prot: P77504-Uncharacterized ABC transporter permease ybbP YP_001534014.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001534015.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001534016.1 Swiss-Prot: P54378-Aminomethyltransferase TIGRFAM: glycine cleavage system T protein PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel YP_001534017.1 Swiss-Prot: P05149-aldose 1-epimerase [Precursor] PFAM: Aldose 1-epimerase YP_001534018.1 Swiss-Prot: Q92UG5-Putative transthyretin-like protein RB1166 TIGRFAM: Hydroxyisourate hydrolase PFAM: Transthyretin YP_001534019.1 Swiss-Prot: P09124-Glyceraldehyde-3-phosphate dehydrogenase 1 PFAM: glyceraldehyde 3-phosphate dehydrogenase TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; phosphorylating YP_001534020.1 Swiss-Prot: P37903-Universal stress protein F PFAM: UspA domain protein KEGG: sit:TM1040_2126 UspA YP_001534021.1 Swiss-Prot: P19567-Pseudoazurin [Precursor] TIGR02375# pseudoazurin YP_001534022.1 Swiss-Prot: P26459-Cytochrome bd-II oxidase subunit 1 PFAM: cytochrome bd ubiquinol oxidase subunit I YP_001534023.1 Swiss-Prot: P0ABK2-Cytochrome d ubiquinol oxidase subunit 2 TIGR00203: cytochrome d oxidase, subunit II (cydB) PFAM: cytochrome bd ubiquinol oxidase subunit II YP_001534024.1 KEGG: jan:Jann_3427 hypothetical protein YP_001534025.1 Swiss-Prot: P0AC84-Probable hydroxyacylglutathione hydrolase ( Glyoxalase II) PFAM: beta-lactamase domain protein KEGG: mlo:mlr3546 putative glyoxalase II YP_001534026.1 PFAM: protein of unknown function DUF1194 YP_001534027.1 PFAM: protein of unknown function DUF606 COG3238: Uncharacterized protein conserved in bacteria YP_001534028.1 SSF46626: Cytochrome c superfamily PS51007: CYTC (Cytochrome c family profile) YP_001534029.1 Swiss-Prot: P27017-Aliphatic amidase expression-regulating protein amiC COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component SSF53822: Periplasmic binding protein-like I superfamily YP_001534030.1 Swiss-Prot: P0AEX7-High-affinity branched-chain amino acid transport system permease protein livH PFAM: inner-membrane translocator SMART: PBS lyase HEAT domain protein repeat-containing protein YP_001534031.1 Swiss-Prot: P22729-High-affinity branched-chain amino acid transport system permease protein livM PFAM: inner-membrane translocator; permease protein YP_001534032.1 Swiss-Prot: P0A9S7-High-affinity branched-chain amino acid transport ATP-binding protein livG PFAM: ABC transporter related SMART: AAA ATPase COG4674: Uncharacterized ABC-type transport system, ATPase component YP_001534033.1 Swiss-Prot: P22731-High-affinity branched-chain amino acid transport ATP-binding protein livF PFAM: ABC transporter related SMART: AAA ATPase COG0410: ABC-type branched-chain amino acid transport systems, ATPase component YP_001534034.1 Swiss-Prot: Q60099-(S)-2-haloacid dehalogenase TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) PFAM: Haloacid dehalogenase domain protein hydrolase YP_001534035.1 PFAM: alpha/beta hydrolase fold KEGG: rsh:Rsph17029_0927 alpha/beta hydrolase fold; alpha/beta hydrolase superfamily YP_001534036.1 Swiss-Prot: P0AGF6-Threonine dehydratase catabolic tdcB PFAM: Pyridoxal-5-phosphate-dependent protein beta subunit; catabolic YP_001534037.1 KEGG: rde:RD1_0908 hypothetical protein YP_001534038.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001534039.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001534040.1 Swiss-Prot: P21503-Uncharacterized MFS-type transporter ycaD PFAM: major facilitator superfamily MFS_1 YP_001534041.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001534042.1 TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein YP_001534043.1 Swiss-Prot: Q92RA4-Peptide methionine sulfoxide reductase msrB 1 TIGRFAM: methionine-R-sulfoxide reductase PFAM: Methionine sulfoxide reductase B YP_001534044.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase TIGR00275: conserved hypothetical protein SSF51905: FAD/NAD(P)-binding domain superfamily YP_001534045.1 Swiss-Prot: P29933-Aerobic cobaltochelatase subunit cobS TIGRFAM: cobalt chelatase, pCobS small subunit PFAM: ATPase associated with various cellular activities AAA_5 YP_001534046.1 Swiss-Prot: Q05197-Phosphatidylethanolamine N-methyltransferase [predicted] PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001534047.1 Swiss-Prot: Q9ZBM2- CDP-diacylglycerol--serine O-phosphatidyltransferase TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase PFAM: CDP-alcohol phosphatidyltransferase YP_001534048.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001534049.1 Swiss-Prot: P25888-Putative ATP-dependent RNA helicase rhlE PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein SMART: DEAD-like helicases YP_001534052.1 SMART: Helix-turn-helix XRE-family like proteins; XRE family YP_001534053.1 Swiss-Prot: P29934-Aerobic cobaltochelatase subunit cobT TIGR01651: cobaltochelatase, CobT subunit PFAM: Cobalt chelatase CobT subunit SMART: von Willebrand factor type A YP_001534054.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001534055.1 PFAM: creatinase; peptidase M24 YP_001534056.1 PFAM: protein of unknown function DUF427 COG2343: Uncharacterized protein conserved in bacteria YP_001534057.1 TIGR00997: intracellular septation protein A PFAM: Intracellular septation protein A YP_001534058.1 PFAM: protein of unknown function DUF6 transmembrane YP_001534059.1 Swiss-Prot: P10121-Cell division protein ftsY TIGRFAM: signal recognition particle-docking protein FtsY PFAM: GTP-binding signal recognition particle SRP54 G- domain SMART: AAA ATPase; related to cell division protein ftsY YP_001534061.1 Swiss-Prot: Q1GF88-Exodeoxyribonuclease 7 large subunit YP_001534062.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001534063.1 PFAM: Ion transport 2 domain protein YP_001534065.1 Swiss-Prot: P80306-Ferredoxin-6 PFAM: ferredoxin YP_001534066.1 PFAM: nucleic acid binding OB-fold tRNA/helicase-type COG0587: DNA polymerase III, alpha subunit; associated with nucleic acid binding YP_001534067.1 Swiss-Prot: P0C0V0-Protease do [Precursor] TIGR02037: periplasmic serine protease, Do/DeqQ family PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001534069.1 Swiss-Prot: P0ABC3-Protein hflC TIGRFAM: HflC protein PFAM: band 7 protein; colocated with hflK YP_001534070.1 Swiss-Prot: P0ABC7-Protein hflK TIGRFAM: HflK protein; colocated with hflC YP_001534071.1 Swiss-Prot: P06715-Glutathione reductase PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_001534072.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001534073.1 TIGRFAM: thiamine pyrophosphokinase PFAM: Thiamin pyrophosphokinase catalytic region YP_001534074.1 PFAM: herpesvirus transcription activation factor; related to transactivator YP_001534075.1 Swiss-Prot: P45566-Uncharacterized protein yhdT YP_001534076.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001534077.1 TIGRFAM: preprotein translocase, SecG subunit PFAM: Preprotein translocase SecG subunit; SecG subunit YP_001534078.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001534079.1 Swiss-Prot: P37757-Uncharacterized isomerase yddE TIGRFAM: phenazine biosynthesis protein PhzF family PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001534080.1 KEGG: rde:RD1_1231 hypothetical protein YP_001534081.1 KEGG: sil:SPO0431 hypothetical protein YP_001534082.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001534083.1 Swiss-Prot: PFAM: Di-haem cytochrome c peroxidase COG1858: Cytochrome c peroxidase Swiss-Prot: [predicted] Q51658-Methylamine utilization protein mauG [Precursor] P37197-Probable cytochrome c peroxidase YP_001534086.1 Swiss-Prot: P44542-Sialic acid-binding periplasmic protein siaP [Precursor] PFAM: TRAP dicarboxylate transporter- DctP subunit COG1638: TRAP-type C4-dicarboxylate transport system, periplasmic component; colocated with DctQ & DctM subunits; DctP subunit YP_001534087.1 Swiss-Prot: P44543-Sialic acid TRAP transporter permease protein TIGRFAM: TRAP dicarboxylate transporter, DctM subunit PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; colocated with DctQ & DctP subunit; DctM subunit YP_001534088.1 Swiss-Prot: P44994-Putative TRAP transporter small permease protein HI1030 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; colocated with DctM & DctP subunits; DctQ component YP_001534089.1 Swiss-Prot: P54990-Nitrilotriacetate monooxygenase component B PFAM: flavin reductase domain protein FMN-binding; FMN-binding YP_001534090.1 Swiss-Prot: P42972-Uncharacterized oxidoreductase ycsN PFAM: aldo/keto reductase COG4989: Predicted oxidoreductase YP_001534091.1 Swiss-Prot: P80645-Alkanesulfonate monooxygenase PFAM: luciferase family protein YP_001534092.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; GntR family YP_001534093.1 Swiss-Prot: O05389-Putative oxidoreductase yrbE PFAM: oxidoreductase domain protein; Oxidoreductase domain COG0673: Predicted dehydrogenases and related proteins YP_001534094.1 Swiss-Prot: P32662-Phosphoglycolate phosphatase TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1 PFAM: Haloacid dehalogenase domain protein hydrolase YP_001534095.1 Swiss-Prot: P0AFU2-Uncharacterized transporter yfbS PFAM: Citrate transporter; TrkA-C domain protein YP_001534096.1 Swiss-Prot: P0A8A0-UPF0082 protein yebC TIGR01033 conserved hypothetical protein COG0217: Uncharacterized conserved protein YP_001534097.1 Swiss-Prot: P09983-Hemolysin, chromosomal PFAM: Hemolysin-type calcium-binding region; related to hemolysin YP_001534100.1 Swiss-Prot: P72958-Uncharacterized transporter sll0640 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001534101.1 PFAM: protein of unknown function DUF6 transmembrane YP_001534102.1 Swiss-Prot: P75429-Uncharacterized protein MG246 homolog TIGR00282# conserved hypothetical protein COG1692: Uncharacterized protein conserved in bacteria YP_001534103.1 Swiss-Prot: P0AC28-Uncharacterized protein ygfA PFAM: 5-formyltetrahydrofolate cyclo-ligase TIGR02727: 5,10-methenyltetrahydrofolate synthetase; related to 5-formyltetrahydrofolate cyclo-ligase YP_001534104.1 TIGR00400: Mg2+ transporter (mgtE) PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region COG2239: Mg/Co/Ni transporter MgtE (contains CBS domain) YP_001534105.1 Catalyzes the deamination of guanine YP_001534106.1 Swiss-Prot: PFAM: SCP-like extracellular COG2340: Uncharacterized protein with SCP/PR1 domains; related to SCP-like extracellular protein YP_001534107.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway. YP_001534108.1 Swiss-Prot: P0ADG4-Inositol-1-monophosphatase suhB TIGRFAM: histidinol-phosphate phosphatase, putative PFAM: inositol monophosphatase YP_001534109.1 Swiss-Prot:Q52911-Uncharacterized HTH-type transcriptional regulator R00410 PFAM: helix-turn-helix domain protein COG1396: Predicted transcriptional regulators SM00530: Helix-turn-helix XRE-family like proteins; XRE family YP_001534110.1 Swiss-Prot: P12311-Alcohol dehydrogenase PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001534111.1 Swiss-Prot:P36771-Probable HTH-type transcriptional regulator lrhA PFAM: regulatory protein LysR; LysR substrate-binding; LysR family YP_001534113.1 Swiss-Prot: P0AAC4-Inner membrane protein ybhL PFAM: protein of unknown function UPF0005 YP_001534115.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001534117.1 Swiss-Prot: P75820-N-acetylmuramoyl-L-alanine amidase amiD [Precursor] PFAM: N-acetylmuramoyl-L-alanine amidase family 2; similar to N-acetylmuramoyl-L-alanine amidase YP_001534119.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001534120.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001534122.1 Swiss-Prot:Q98M91- UPF0173 metal-dependent hydrolase PFAM:beta-lactamase domain protein COG2220: Predicted Zn-dependent hydrolases of the beta-lactamase fold YP_001534123.1 Swiss-Prot: P68398- tRNA-specific adenosine deaminase tadA PFAM: CMP/dCMP deaminase zinc-binding PTHR11079: cytidine / deoxycytidylate deaminase-related; related to cytidine / deoxycytidylate deaminase YP_001534124.1 Swiss-Prot: Q4UL59-Uncharacterized RNA pseudouridine synthase RF_0863 TIGR00093: pseudouridine synthase family COG1187:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases YP_001534125.1 KEGG: sil:SPO2985 hypothetical protein YP_001534126.1 PFAM: toxic anion resistance family protein Swiss-Prot: Q2YY12- TelA-like protein SAB1262 COG3853: Uncharacterized protein involved in tellurite resistance; related to toxic anion resistance protein (TelA) YP_001534130.1 PFAM: heat shock protein Hsp20 SSF49764: HSP20-like chaperones superfamily; Hsp20 YP_001534131.1 PFAM: PfkB domain protein COG0524: Sugar kinases, ribokinase family PTHR10584: sugar kinase related; pfkB family YP_001534132.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001534133.1 Swiss-Prot: Q06530- Sulfide dehydrogenase [flavocytochrome c] flavoprotein chain [Precursor] PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Flavocytochrome c sulphide dehydrogenase flavin-binding YP_001534134.1 Swiss-Prot: P00082-Cytochrome c2 PFAM: cytochrome c class I YP_001534135.1 Swiss-Prot: P00081-Cytochrome c2 PFAM: cytochrome c class I YP_001534136.1 Swiss-Prot: PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; molybdopterin binding YP_001534137.1 PFAM: metallophosphoesterase; 5-Nucleotidase domain protein Swiss-Prot:P07024-Protein ushA [Precursor] COG0737: 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases YP_001534138.1 Swiss-Prot: Q939U1-Diheme cytochrome c GENE3D / SSF46626: Cytochrome c, monohaem PS51008: Multihaem cytochrome YP_001534139.1 PFAM: Sulphur oxidation protein SoxZ Swiss-Prot: Q939U2- SoxZ [predicted]; soxZ YP_001534140.1 with SoxZ catalyzes the oxidation of sulfur compounds YP_001534141.1 PFAM: cytochrome c SSF46626 / PS51007 / G3DSA:1.10.760.10: Cytochrome c, monohaem Swiss-Prot: A3W521- Monoheme cytochrome c SoxX [predicted]; monohaem YP_001534142.1 SSF52833: Thioredoxin-like superfamily COG2143: Thioredoxin-related protein Swiss-Prot: Q16A50-Thioredoxin SoxW [predicted] YP_001534143.1 PFAM: cytochrome c biogenesis protein transmembrane region COG0785: Cytochrome c biogenesis protein; transmembrane region YP_001534145.1 PFAM: protein of unknown function DUF336 YP_001534146.1 PFAM: regulatory protein ArsR; ArsR family YP_001534147.1 PFAM: protein of unknown function DUF395 YeeE/YedE YP_001534148.1 TIGRFAM: diguanylate cyclase (GGDEF) domain PFAM: GGDEF domain containing protein YP_001534149.1 PFAM: Heme NO binding domain protein YP_001534151.1 Swiss-Prot: PFAM: trimethylamine methyltransferase PIRSF037567: trimethylamine methyltransferase, MttB type YP_001534152.1 Swiss-Prot: P32662-Phosphoglycolate phosphatase TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1 PFAM: Haloacid dehalogenase domain protein hydrolase YP_001534153.1 KEGG: sil:SPO2752 hypothetical protein YP_001534154.1 Swiss-Prot: Q9A5I5-Response regulator pleD (part of a signal transduction pathway controlling cell differentiation in the swarmer-to-stalked cell transition) TIGR00254: diguanylate cyclase (GGDEF) domain PFAM: GGDEF domain containing protein; response regulator receiver YP_001534155.1 PFAM: protein of unknown function DUF983 COG5349: Uncharacterized protein conserved in bacteria YP_001534156.1 Swiss-Prot: PFAM: NUDIX hydrolase YP_001534157.1 PFAM: aldo/keto reductase IPR001395: Aldo/keto reductase YP_001534159.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding COG1250: 3-hydroxyacyl-CoA dehydrogenase; related to 3-hydroxyacyl-CoA dehydrogenase YP_001534160.1 KEGG: rde:RD1_2519 hypothetical protein COG4544: Uncharacterized conserved protein YP_001534161.1 Swiss-Prot: P0A8X2-Protein yceI [Precursor] PFAM: YceI family protein COG2353: Uncharacterized conserved protein; similar to protein yceI [Precursor] YP_001534162.1 Swiss-Prot: TIGRFAM: Mg chelatase, subunit ChlI PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5 SMART: AAA ATPase; related to Mg chelatase YP_001534163.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001534164.1 TIGR00252 conserved hypothetical protein PFAM: protein of unknown function UPF0102 YP_001534165.1 Swiss-Prot: P67087-UPF0011 protein yraL TIGR00096: conserved hypothetical protein TIGR00096 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001534166.1 SSF53822: Periplasmic binding protein-like I superfamily PS51257: Prokaryotic membrane lipoprotein lipid attachment site profile YP_001534167.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001534168.1 Swiss-Prot: O05467-Virulence factor mviN homolog TIGRFAM: integral membrane protein MviN PFAM: virulence factor MVIN family protein COG072: Uncharacterized membrane protein, putative virulence factor; mviN homolog YP_001534169.1 PFAM: Rhomboid family protein KEGG: sit:TM1040_0444 rhomboid-like protein COG0705: Uncharacterized membrane protein (homolog of Drosophila rhomboid); related to rhomboid family protein YP_001534170.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001534171.1 Swiss-Prot: P0AB80-Branched-chain-amino-acid aminotransferase PFAM: aminotransferase class IV; class IV YP_001534172.1 PFAM: UspA domain protein COG0589: Universal stress protein UspA and related nucleotide-binding proteins; related to universal stress protein YP_001534173.1 PFAM: nitrogen-fixing NifU domain protein; Scaffold protein Nfu/NifU Swiss-Prot: P33179-Nitrogen fixation protein nifU [Fragment] (inferred from homology); related to nitrogen fixation protein YP_001534174.1 PFAM: peptidase M22 glycoprotease; glycoprotease YP_001534175.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase Swiss-Prot: P0A947-Ribosomal-protein-alanine acetyltransferase [inferred from homology] PFAM: GCN5-related N-acetyltransferase YP_001534176.1 PFAM: basic membrane lipoprotein SSF53822: Periplasmic binding protein-like I superfamily YP_001534177.1 Swiss-Prot: P04983-Ribose import ATP-binding protein rbsA YP_001534178.1 Swiss-Prot: P0AGI1-Ribose transport system permease protein rbsC PFAM: inner-membrane translocator; similar to ribose transport system permease protein YP_001534179.1 PFAM: Lysine exporter protein (LYSE/YGGA) Swiss-Prot: P75693-Uncharacterized membrane protein yahN; related to LysE type translocator YP_001534180.1 PFAM: inner-membrane translocator COG1079: Uncharacterized ABC-type transport system, permease component YP_001534181.1 Swiss-Prot: PFAM: protein of unknown function DUF81 KEGG: sil:SPO0375 membrane protein YP_001534182.1 TIGR02186# conserved hypothetical protein YP_001534183.1 Swiss-Prot: Q9KWN1-Serine 3-dehydrogenase PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR COG4221: Short-chain alcohol dehydrogenase of unknown specificity YP_001534184.1 SMART 00382: AAA - ATPases associated with a variety of cellular activities; AAA family YP_001534185.1 Swiss-Prot: P33883-Autoinducer synthesis protein lasI PFAM: autoinducer synthesis protein YP_001534186.1 ibu, PFAM: regulatory protein LuxR; Autoinducer-binding domain protein KEGG: sil:SPO0371 autoinducer-binding transcriptional regulator LuxR, Autoinducer binding domain pfam03472, HTH-LuxR domain pfam00196; LuxR family YP_001534187.1 TIGRFAM: crotonyl-CoA reductase PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein Swiss-Prot: P42328-Alcohol dehydrogenase YP_001534188.1 Swiss-Prot: P0A7A7-Glycerol-3-phosphate acyltransferase PFAM: phospholipid/glycerol acyltransferase YP_001534189.1 Swiss-Prot: PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein TIGR00640: methylmalonyl-CoA mutase C-terminal domain TIGR00641: methylmalonyl-CoA mutase N-terminal domain YP_001534192.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001534195.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001534199.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001534200.1 TIGRFAM: TIGR02968 succinate dehydrogenase, hydrophobic membrane anchor protein; COG: COG2142 - Succinate dehydrogenase, hydrophobic anchor subunit; similar to succinate dehydrogenase YP_001534201.1 SWISSPROT P69054: Succinate dehydrogenase cytochrome b556 subunit sdhC; TIGRFAM: TIGR02970 succinate dehydrogenase, cytochrome b556 subunit; COG: COG2009 - Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; PFAM: PF01127 - Succinate dehydrogenase cytochrome b subunit; PIR: PIRSF000178 - succinate dehydrogenase, cytochrome b560 subunit; PROSITE: PS01001 YP_001534202.1 SWISSPROT Q3J2P2: Cytochrome c-554 [Precursor] cycF; COG: COG3909 - Cytochrome c556; PFAM: PF01322; PIR: PIRSF000027; PRINTS: PR00608; PROSITE: PS51009; Gene3D: G3DSA:1.20.120.10 YP_001534203.1 SWISSPROT P0A388: Alcohol dehydrogenase cytochrome c subunit [Precursor] adhB; COG: COG2010 - Cytochrome c, mono- and diheme variants; PROSITE: PS51007; SUPERFAMILY: SSF46626 YP_001534205.1 COG: COG2030 - Acyl dehydratase; PIR: PIRSF021494; SUPERFAMILY: SSF54637 YP_001534206.1 COG: COG5515 - Uncharacterized conserved small protein YP_001534207.1 COG: COG4094 - Predicted membrane protein; PFAM: PF07298 - NnrU protein YP_001534208.1 PIR: PIRSF015582 - citrate lyase, beta subunit; PFAM: PF03328; COG: COG2301 - Citrate lyase beta subunit; Gene3D: G3DSA:3.20.20.60 YP_001534210.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001534212.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001534216.1 SWISSPROT P0AGE9: Succinyl-CoA ligase [ADP-forming] subunit alpha; PIR: PIRSF001553 - succinyl-CoA synthetase, alpha subunit; TIGRFAM: TIGR01019 succinyl-CoA synthetase, alpha subunit; COG: COG0074; PFAM: PF02629, PF00549; PROSITE: PS00399, PS01216; PRINTS: PR01798 YP_001534217.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001534218.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001534219.1 COG: COG3686 - Predicted membrane protein YP_001534220.1 SWISSPROT P14218: Dihydrolipoyl dehydrogenase; TIGRFAM: TIGR01350 dihydrolipoamide dehydrogenase; COG: COG1249 - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; PFAM: PF00070, PF02852, PF07992; PRINTS: PR00945, PR00411, PR00368 YP_001534221.1 TIGRFAM: TIGR01780 succinic semialdehyde dehydrogenase; COG: COG1012 - NAD-dependent aldehyde dehydrogenases; PFAM: PF00171; PROSITE: PS00070, PS00687 YP_001534222.1 SUPERFAMILY: SSF53474; Gene3D: G3DSA:3.40.50.1820; COG: COG0657 - Esterase/lipase YP_001534223.1 COG: COG3191 - L-aminopeptidase/D-esterase YP_001534225.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001534226.1 SWISSPROT P0C054: Small heat shock protein ibpA; PFAM: PF00011; PROSITE: PS01031; SUPERFAMILY: SSF49764; COG: COG0071 - Molecular chaperone (small heat shock protein) YP_001534227.1 COG: COG3591 - V8-like Glu-specific endopeptidase; PFAM: PF00089; SMART: SM00020; PROSITE: PS00134, PS50240; PRINTS: PR00722; similar to serine protease YP_001534228.1 COG: COG0247 - Fe-S oxidoreductase; PFAM: PF00037, PF02754; PROSITE: PS00198; SWISSPROT P52074: Glycolate oxidase iron-sulfur subunit; similar to glycolate oxidase iron-sulfur subunit YP_001534229.1 COG: COG0277 - FAD/FMN-containing dehydrogenases; PFAM: PF01565; similar to glycolate oxidase subunit glcE YP_001534230.1 TIGRFAM: TIGR00387 glycolate oxidase, subunit GlcD; COG: COG0277 - FAD/FMN-containing dehydrogenases; PFAM: PF01565, PF02913; SWISSPROT P0AEP9: Glycolate oxidase subunit glcD; similar to glycolate oxidase subunit glcD YP_001534231.1 SWISSPROT P23461: Protein pucD; associated with puc operon, related to protein pucD YP_001534232.1 SWISSPROT P23462: Protein pucC; PFAM: PF03209 YP_001534233.1 SWISSPROT P95655: Light-harvesting protein B-800/850 alpha chain; PFAM: PF00556; PRINTS: PR00673; PROSITE: PS00968; pucA YP_001534234.1 SWISSPROT P07368: Light-harvesting protein B-800/850 beta chain; PFAM: PF00556; PRINTS: PR00674; PROSITE: PS00969 YP_001534238.1 TIGRFAM: TIGR02226 YP_001534239.1 PFAM: PF01882; COG: COG1721 - Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); related to DUF58 YP_001534240.1 COG: COG0714 - MoxR-like ATPases; PFAM: PF07726; SMART: SM00382; related to AAA ATPase YP_001534241.1 COG: COG3816 - Uncharacterized protein conserved in bacteria; PFAM: PF06938 - Protein of unknown function (DUF1285) YP_001534242.1 SWISSPROT P75966: Ribosomal large subunit pseudouridine synthase E; TIGRFAM: TIGR00093 pseudouridine synthase family; COG: COG1187 - 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; PFAM: PF00849 - RNA pseudouridylate synthase; PROSITE: PS01149 YP_001534243.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001534244.1 TIGRFAM: TIGR01065 channel protein, hemolysin III family; COG: COG1272 - Predicted membrane protein, hemolysin III homolog; PFAM: PF03006; related to haemolysin-III family protein YP_001534245.1 TIGRFAM: TIGR02117 conserved hypothetical protein YP_001534246.1 COG: COG4391 - Uncharacterized protein conserved in bacteria YP_001534247.1 SWISSPROT P36879: Uncharacterized ABC transporter ATP-binding protein yadG; PFAM: PF00005; PROSITE: PS00211, PS50893 YP_001534248.1 COG: COG1075 - Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold; PROSITE: PS51257; SUPERFAMILY: SSF53474 YP_001534249.1 SWISSPROT Q58549: ADP-ribose pyrophosphatase; COG: COG1051 - ADP-ribose pyrophosphatase PFAM: PF00293; PRINTS: PR00502; Gene3D: G3DSA:3.90.79.10; related to ADP-ribose pyrophosphatase YP_001534250.1 PFAM: PF00892 - integral membrane protein DUF6; COG: COG5006 - Predicted permease, DMT superfamily; similar to integral membrane protein DUF6 YP_001534251.1 TIGRFAM: TIGR02318 phosphonate metabolism protein PhnM; COG: COG3454 - Metal-dependent hydrolase involved in phosphonate metabolism; PFAM: PF01979 - Amidohydrolase family; similar to amidohydrolase YP_001534252.1 PFAM: Acetyltransferase (GNAT) family; PROSITE: PS51186; COG: COG3153 - Predicted acetyltransferase; similar to acetyltransferase (GNAT) YP_001534253.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001534254.1 COG: COG0234 - Co-chaperonin GroES (HSP10); PFAM: PF00166; PROSITE: PS00681; PRINTS: PR00297 YP_001534256.1 COG: COG5482 - Uncharacterized conserved protein YP_001534257.1 PFAM: PF07694; related to 5TMR of 5TMR-LYT YP_001534258.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001534259.1 TIGRFAM: TIGR01459 HAD-superfamily class IIA hydrolase, TIGR01459 TIGR01460 Haloacid Dehalogenase Superfamily Class (subfamily) IIA; COG: COG0647 - Predicted sugar phosphatases of the HAD superfamily; PFAM: PF00702 YP_001534260.1 SWISSPROT P77455: Protein maoC; PFAM: PF01575; COG: COG2030 - Acyl dehydratase YP_001534261.1 SWISSPROT P0AG40: Riboflavin biosynthesis protein; TIGRFAM: TIGR00083 riboflavin kinase/FMN adenylyltransferase; COG: COG0196 - FAD synthase; PFAM: PF06574; Gene3D: G3DSA:3.40.50.620 YP_001534262.1 COG: COG2983 - Uncharacterized conserved protein; PFAM: PF03692 - Uncharacterized protein family (UPF0153) YP_001534263.1 COG: COG0596 - Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); PFAM: PF00561; PRINTS: PR00412, PR00111; PROSITE: PS00120 YP_001534264.1 COG: COG3917 - 2-hydroxychromene-2-carboxylate isomerase; SWISSPROT Q51948: 2-hydroxychromene-2-carboxylate isomerase nahD YP_001534265.1 SWISSPROT P0A717: ribose-phosphate pyrophosphokinase; TIGRFAM: TIGR01251 ribose-phosphate pyrophosphokinase; COG: COG0462 - Phosphoribosylpyrophosphate synthetase; PFAM: PF00156; PROSITE: PS00114 YP_001534266.1 associated with ATP synthase gene cluster YP_001534267.1 PFAM: PF02823; TIGRFAM: TIGR01216 ATP synthase, F1 epsilon subunit (delta in mitochondria); COG: COG0355 - F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) YP_001534268.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001534269.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001534270.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001534271.1 SWISSPROT P72244: ATP synthase delta chain; TIGRFAM: TIGR01145 ATP synthase, F1 delta subunit; COG: COG0712 - F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); PFAM: PF00213; PROSITE: PS00389 YP_001534273.1 SWISSPROT P0ABH9: ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: TIGR02639 ATP-dependent Clp protease ATP-binding subunit clpA; COG: COG0542 - ATPases with chaperone activity, ATP-binding subunit; PFAM: PF00004, PF02861, PF07724 YP_001534274.1 COG: COG1360 - Flagellar motor protein; PFAM: PF00691; PROSITE: PS51123; related to OmpA YP_001534276.1 PFAM: PF04752 - ChaC-like protein; SWISSPROT P39163: Cation transport protein chaC; COG: COG3703 - Uncharacterized protein involved in cation transport YP_001534278.1 COG: COG3921 - Uncharacterized protein conserved in bacteria; PFAM: PF06904; related to extensin YP_001534279.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate YP_001534280.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001534281.1 SWISSPROT O32323: Homospermidine synthase; PFAM: PF06408 - Homospermidine synthase; COG: COG5310 - Homospermidine synthase YP_001534282.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001534283.1 TIGRFAM: TIGR02504 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; COG: COG0209 - Ribonucleotide reductase, alpha subunit YP_001534284.1 PFAM: PF07370 - Protein of unknown function (DUF1489); COG: COG5458 - Uncharacterized conserved protein YP_001534285.1 COG: COG0031 - Cysteine synthase; PFAM: PF00291; PROSITE: PS00216; similar to cysteine synthase YP_001534286.1 TIGRFAM: TIGR00018 pantoate--beta-alanine ligase; COG: COG0414 - Panthothenate synthetase; PFAM: PF02569 - Pantoate-beta-alanine ligase YP_001534287.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001534288.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001534289.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001534290.1 PFAM: PF04102- SlyX; similar to slyX YP_001534291.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001534292.1 PFAM: PF00111, PF00941, PF01799, PF03450; TIGRFAM: TIGR02963 xanthine dehydrogenase, small subunit; COG: COG4630 - Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A; iron-sulfur-binding subunit and FAD-binding subunit YP_001534293.1 SWISSPROT Q46799: Xanthine dehydrogenase molybdenum-binding subunit; TIGRFAM: TIGR02965 xanthine dehydrogenase, molybdopterin binding subunit; COG: COG4631 - Xanthine dehydrogenase, molybdopterin-binding subunit B YP_001534294.1 TIGRFAM: TIGR02964 xanthine dehydrogenase accessory protein XdhC; PFAM: PF02625; COG: COG1975 - Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family YP_001534295.1 COG: COG3845 - ABC-type uncharacterized transport systems, ATPase components; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382 YP_001534296.1 COG: COG4603 - ABC-type uncharacterized transport system, permease component; PFAM: PF02653-Branched-chain amino acid transport system / permease component; permease component YP_001534297.1 COG: COG1079 - Uncharacterized ABC-type transport system, permease component; PFAM: PF02653-Branched-chain amino acid transport system / permease component; permease component YP_001534298.1 PFAM: PF02608; SUPERFAMILY: SSF53822 YP_001534300.1 TIGRFAM: TIGR00222 3-methyl-2-oxobutanoate hydroxymethyltransferase; COG: COG0413 - Ketopantoate hydroxymethyltransferase; PFAM: PF02548 Ketopantoate hydroxymethyltransferase YP_001534301.1 COG: COG0404 - Glycine cleavage system T protein (aminomethyltransferase); PFAM: PF01266, PF01571, PF08669 YP_001534303.1 COG: COG0599 - Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; TIGRFAM: TIGR00778; PFAM: PF02627; SUPERFAMILY: SSF69118; Gene3D: G3DSA:1.20.1290.10; related to alkylhydroxyperoxidase YP_001534304.1 COG: COG1052 - Lactate dehydrogenase and related dehydrogenases; PFAM: PF00389, PF02826; PROSITE: PS00065, PS00671 YP_001534305.1 PFAM: PF06347; COG: COG3807 - Uncharacterized protein conserved in bacteria YP_001534306.1 PFAM: PF00989, PROSITE: PS50112, SMART: SM00091 YP_001534307.1 SWISSPROT P27236: Peptidyl-dipeptidase dcp; COG: COG0339 - Zn-dependent oligopeptidases; PFAM: PF01432; PROSITE: PS00142 YP_001534308.1 SWISSPROT P12282: Molybdopterin biosynthesis protein moeB; COG: COG0476 - Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; PFAM: PF00899, PF05237 YP_001534309.1 PFAM: PF00692- dUTPase; TIGRFAM: TIGR00576 deoxyuridine 5-triphosphate nucleotidohydrolase (dut); COG: COG0756 - dUTPase YP_001534310.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001534311.1 PFAM: PF04187 - Protein of unknown function DUF399; COG: COG3016 - Uncharacterized iron-regulated protein YP_001534312.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production YP_001534313.1 SWISSPROT P29931: Bifunctional adenosylcobalamin biosynthesis protein cobP; PFAM: PF02283 - Cobinamide kinase / cobinamide phosphate guanyltransferase; PIR: PIRSF006135 - bifunctional cobinamide kinase/cobinamide phosphate guanyltransferase; COG: COG2087 - Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase YP_001534314.1 PFAM: PF00300; related to phosphoglycerate mutase YP_001534315.1 COG: COG2041 - Sulfite oxidase and related enzymes; PFAM: PF00174, PF03404; PRINTS: PR00407; SUPERFAMILY: SSF56524, SSF81296 YP_001534316.1 PROSITE: PS51257; SUPERFAMILY: SSF46626; related to cytochrome c YP_001534317.1 COG:COG2130 - Putative NADP-dependent oxidoreductases; PFAM: PF00107; SUPERFAMILY: SSF50129; PANTHER: Alcohol dehydrogenase related; related to zinc-binding dehydrogenase YP_001534318.1 COG: COG0625 - Glutathione S-transferase; SUPERFAMILY: SSF52833, SSF47616; Gene3D: G3DSA:3.40.30.10; similar to glutathione S-transferase YP_001534319.1 COG: COG1802 - Transcriptional regulators; PFAM: PF00392, PF07729; PROSITE: PS50949; Gene3D: G3DSA:1.10.10.10; GntR type YP_001534320.1 COG: COG1451 - Predicted metal-dependent hydrolase; PFAM: PF01863 - Protein of unknown function DUF45; PROSITE: PS00142 YP_001534321.1 TIGRFAM: TIGR02300 conserved hypothetical protein; PROSITE: PS00018 YP_001534322.1 PFAM: PF01906; COG: COG0393 - Uncharacterized conserved protein YP_001534323.1 PROSITE: PS51257; related to membrane lipoprotein YP_001534324.1 COG: COG4333 - Uncharacterized protein conserved in bacteria; PFAM: PF00126, PF03466; PROSITE: PS5093; Gene3D: G3DSA:1.10.10.10; LysR family YP_001534325.1 PFAM: PF07799-Protein of unknown function (DUF1643); COG: COG4333 - Uncharacterized protein conserved in bacteria YP_001534326.1 SWISSPROT Q01398: Haloacetate dehalogenase H-1; COG: COG0596 - Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); PFAM: PF00561; PRINTS: PR00412, PR00111 YP_001534328.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001534330.1 COG: COG3568 - Metal-dependent hydrolase; PFAM: PF03372; PROSITE: PS51257; SUPERFAMILY: SSF56219; similar to Endonuclease/Exonuclease/Phosphatase family YP_001534331.1 SWISSPROT P05055: Polyribonucleotide nucleotidyltransferase; COG: COG1185 - Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); PFAM: PF01138, PF00575, PF00013, PF03725, PF03726; SMART: SM00322 YP_001534332.1 COG: COG0668 - Small-conductance mechanosensitive channel; PFAM: PF00924; SUPERFAMILY: SSF82689, SSF82861, SSF50182 YP_001534333.1 catalyzes the formation of malonyl-CoA from malonate and CoA YP_001534334.1 PFAM: Malonyl-CoA decarboxylase KEGG: rde:RD1_1475 malonyl-CoA decarboxylase. Good Pfam hit, good BLAST hit to several Roseobacter species, RBS 10nt upstream YP_001534335.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit KEGG: rde:RD1_1476 TrapT family, DctM subunit, putative. Good BLAST hit to Rhodobacterales, gene cluster YP_001534336.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component . BLAST hit to Proteobacteria YP_001534337.1 PFAM: TRAP dicarboxylate transporter- DctP subunit KEGG: rde:RD1_1478 C4-dicarboxylate transport system C4-dicarboxylate-binding protein, putative. BLAST hit, good RBS 6nt upstream YP_001534338.1 PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: rde:RD1_1479 GntR-family transcription regulator, putative; GntR family YP_001534340.1 PFAM: ribulose-phosphate 3-epimerase KEGG: rsp:RSP_2864 pentose-5-phosphate-3-epimerase YP_001534341.1 PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; Glycoside hydrolase family 38 central region KEGG: jan:Jann_2057 alpha-mannosidase YP_001534342.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein SMART: AAA ATPase KEGG: jan:Jann_2056 ABC transporter related. Contain duplicated ATPase; ATPase subunit YP_001534343.1 contain signal peptide und Transmembrane Helices; MSD YP_001534344.1 contain signal peptide und Transmembrane Helices; MSD YP_001534345.1 contain signal peptide, RBS 5nt upstream; periplasmic component YP_001534346.1 KEGG: jan:Jann_2052 Zn-dependent hydrolase of the beta-lactamase fold YP_001534347.1 PFAM: protein of unknown function DUF606 KEGG: jan:Jann_1137 protein of unknown function DUF606 ; TMH YP_001534348.1 PFAM: Phytanoyl-CoA dioxygenase KEGG: jan:Jann_2051 phytanoyl-CoA dioxygenase YP_001534349.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation KEGG: jan:Jann_2050 transcriptional regulator, AraC family; AraC family YP_001534350.1 KEGG: jan:Jann_0789 deoxyribose-phosphate aldolase TIGRFAM: deoxyribose-phosphate aldolase PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; DERA; Deoxyriboaldolase YP_001534351.1 PFAM: aldehyde dehydrogenase KEGG: sil:SPO3368 aldehyde dehydrogenase family protein YP_001534352.1 PFAM: protein of unknown function DUF1523 YP_001534354.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001534355.1 PFAM: aldehyde dehydrogenase KEGG: sil:SPO0097 aldehyde dehydrogenase family protein; Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase YP_001534356.1 PFAM: PfkB domain protein KEGG: jan:Jann_1671 PfkB; rde:RD1_0962 PfkB family kinase, putative YP_001534357.1 KEGG: sil:SPO3581 endonuclease III TIGRFAM: endonuclease III PFAM: helix-hairpin-helix motif; HhH-GPD family protein SMART: iron-sulfur cluster loop YP_001534358.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase PFAM: helix-turn-helix- domain containing protein AraC type; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding KEGG: sil:SPO3578 ADA regulatory protein YP_001534359.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen KEGG: rsq:Rsph17025_0195 OmpA/MotB domain protein YP_001534360.1 PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: rde:RD1_1326 pdhR; pyruvate dehydrogenase complex repressor YP_001534361.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel. YP_001534362.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B' is part of the membrane proton channel. YP_001534363.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001534364.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001534365.1 KEGG: rde:RD1_1321 ATP synthase F0, subunit I; I subunit YP_001534366.1 PFAM: Heparinase II/III family protein KEGG: rde:RD1_0654 hypothetical protein; sit:TM1040_0090 heparinase II/III-like YP_001534367.1 PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; methyltransferase small; Methyltransferase type 11 KEGG: rsh:Rsph17029_2765 Fmu (Sun) domain protein; 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase YP_001534368.1 PFAM: protein of unknown function DUF1674 YP_001534369.1 KEGG: jan:Jann_4038 hypothetical protein YP_001534370.1 colocated with MFP subunit; pfam00873,; RND family, RND subunit YP_001534371.1 colocated with RND subunit; TIGRFAM: efflux transporter, RND family, MFP subunit PFAM: secretion protein HlyD family protein KEGG: jan:Jann_1310 secretion protein HlyD; RND family, MFP subunit YP_001534372.1 PFAM: regulatory protein TetR KEGG: rpb:RPB_3412 transcriptional regulator, TetR family; TetR family YP_001534373.1 PFAM: BLUF domain protein KEGG: rpe:RPE_3231 BLUF domain protein. Good BLAST hit to several Rhodobacteraceae species, pfam04940, RBS 10nt upstream YP_001534374.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001534375.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001534376.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001534377.1 PFAM: protein of unknown function DUF1294 KEGG: ret:RHE_CH01861 putative inner membrane protein, predicted 3TMH YP_001534378.1 PFAM: Tannase and feruloyl esterase KEGG: psa:PST_1665 tannase precursor; BLAST hit to Rhodobacteraceae, RBS 5nt upstream YP_001534379.1 PFAM: glycosyl transferase family 2 KEGG: rde:RD1_0635 glycosyl transferase, putative YP_001534380.1 PFAM: MOFRL domain protein KEGG: rso:RSp1449 probable hydroxypyruvate reductase oxidoreductase protein YP_001534381.1 COG2084 MmsB - 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases PFAM: oxidoreductase domain protein; 6-phosphogluconate dehydrogenase NAD-binding KEGG: jan:Jann_3485 3-hydroxyisobutyrate dehydrogenase; TSAR; Tartronate semialdehyde reductase YP_001534382.1 PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: bbr:BB2654 GntR-family transcriptional regulator COG2186:FadR, PRK10225 ; GntR domain protein KEGG: bbr:BB2654 GntR-family transcriptional regulator YP_001534383.1 RBS 7nt upstream PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase KEGG: acr:Acry_2399 NAD-dependent epimerase/dehydratase YP_001534384.1 PFAM: HpcH/HpaI aldolase KEGG: rsq:Rsph17025_2481 citrate (pro-3S)-lyase YP_001534386.1 N-terminal elongation? Mu phage related? YP_001534387.1 rde:RD1_0339 transposase, putative YP_001534388.1 PFAM: phospholipid/glycerol acyltransferase KEGG: sit:TM1040_3500 phospholipid/glycerol acyltransferas,COG0204 YP_001534389.1 SY, PFAM: protein of unknown function DUF214 KEGG: rsh:Rsph17029_2388 protein of unknown function DUF214 , COG2177, conserved neighborhood regions (with COG2884 and COG0204) YP_001534390.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: rde:RD1_1599 ftsE; cell division ATP-binding protein, putative YP_001534391.1 TIGRFAM: MJ0042 family finger-like protein KEGG: sil:SPO0336 hypothetical protein, Bad blast, but this protein contains a CXXCX(19)CXXC motif suggestive of MJ0042 family YP_001534392.1 TIGRFAM: conserved hypothetical protein TIGR02302 KEGG: sil:SPO0335 hypothetical protein YP_001534393.1 TIGRFAM: diaminopimelate decarboxylase PFAM: Orn/DAP/Arg decarboxylase 2 KEGG: jan:Jann_0481 diaminopimelate decarboxylase; DAP decarboxylase YP_001534394.1 KEGG: rsq:Rsph17025_2447 hypothetical protein, RBS YP_001534396.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001534397.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein Swissprot: Thiol:disulfide interchange protein tlpA (Cytochrome c biogenesis protein tlpA); Cytochrome c biogenesis protein TlpA YP_001534398.1 KEGG: rsq:Rsph17025_2464 DNA-3-methyladenine glycosylase I TIGRFAM: DNA-3-methyladenine glycosylase I PFAM: methyladenine glycosylase YP_001534399.1 PFAM: EAL domain protein KEGG: pde:Pden_2025 diguanylate phosphodiesterase , DUF2 YP_001534400.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001534401.1 TIGRFAM: acetoacetyl-CoA reductase PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein KEGG: jan:Jann_0492 acetoacetyl-CoA reductase; 3-ketoacyl-acyl carrier protein reductase; 3-oxoacyl-[acyl-carrier-protein] reductase YP_001534402.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001534403.1 PFAM: protein of unknown function DUF465 KEGG: pde:Pden_2028 protein of unknown function DUF465, COG5570 YP_001534404.1 KEGG: rsp:RSP_0748 N-6 adenine-specific DNA methylase ;pfam05175 MTS Methyltransferase small domain; COG4123 Predicted O-methyltransferase YP_001534405.1 pfam09413 Protein of unknown function (DUF2007) KEGG: rde:RD1_3400 hypothetical protein YP_001534406.1 PFAM: Polyprenyl synthetase KEGG: rsh:Rsph17029_2406 trans-hexaprenyltranstransferase YP_001534407.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001534408.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein SMART: Tetratricopeptide domain protein KEGG: sil:SPO0317 TPR domain protein. Annotation was derived from R. denitrificans YP_001534409.1 pfam05187 FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase KEGG: rde:RD1_3404 electron transfer flavoprotein-ubiquinone oxidoreductase, putative COG0644; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF-ubiquinone oxidoreductase; ETF-QO YP_001534410.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001534411.1 KEGG: sil:SPO0311 hypothetical protein YP_001534412.1 PFAM: AzlC family protein KEGG: rsq:Rsph17025_2457 AzlC family protein YP_001534413.1 PFAM: branched-chain amino acid transport pfam05437AzlDKEGG: rde:RD1_3412 hypothetical protein ; Neighborhood with AzlC family protein ; predicted TMH YP_001534414.1 colocated with RND subunit; TIGRFAM: efflux transporter, RND family, MFP subunit PFAM: secretion protein HlyD family protein KEGG: jan:Jann_1310 secretion protein HlyD; RND family, MFP subunit YP_001534415.1 colocated with MFP subunit; pfam00873,; RND family, RND subunit YP_001534416.1 KEGG: rsh:Rsph17029_2660 hypothetical protein ,COG4233 YP_001534417.1 pfam02622,DUF179,COG1678 Putative transcriptional regulator; KEGG: rde:RD1_3419 hypothetical protein YP_001534418.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein PFAM: SUA5 domain protein; SUA5/yciO/yrdC domain KEGG: pde:Pden_0435 SUA5/YciO/YrdC/YwlC family protein YP_001534419.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain KEGG: sil:SPO0298 acyl-CoA dehydrogenase family protein; rde:RD1_3417 putative acyl-CoA YP_001534420.1 PFAM: beta-lactamase domain protein KEGG: rsh:Rsph17029_2397 beta-lactamase domain protein YP_001534421.1 45aa protein PFAM: aa3 type cytochrome c oxidase subunit IV YP_001534422.1 KEGG: rsh:Rsph17029_2395 hypothetical protein YP_001534423.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B PFAM: molybdopterin binding domain KEGG: sil:SPO0291 molybdenum cofactor biosynthesis protein B YP_001534424.1 TIGRFAM: phage SPO1 DNA polymerase-related protein PFAM: Uracil-DNA glycosylase superfamily KEGG: sil:SPO0288 uracil-DNA glycosylase; rde:RD1_3425 udgA; uracil-DNA glycosylase, C-terminal YP_001534425.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001534428.1 KEGG: rsh:Rsph17029_2663 dihydroorotase, multifunctional complex type TIGRFAM: dihydroorotase, multifunctional complex type PFAM: amidohydrolase; DHOase YP_001534429.1 PFAM: protein of unknown function DUF205 KEGG: jan:Jann_3906 protein of unknown function DUF205 , COG0344, COG0344 YP_001534430.1 PFAM: protein of unknown function DUF805 KEGG: jan:Jann_3908 protein of unknown function DUF805,COG3152 - Predicted membrane protein YP_001534431.1 KEGG: sil:SPO3626 glutamate-cysteine ligase TIGRFAM: glutamate--cysteine ligase PFAM: glutamate--cysteine ligase GCS2 YP_001534433.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001534434.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001534435.1 PFAM: OmpA/MotB domain protein KEGG: sit:TM1040_3081 OmpA/MotB. Annotation was derived from R. denitrificans YP_001534436.1 KEGG: rsh:Rsph17029_2670 hypothetical protein YP_001534437.1 PFAM: molybdopterin biosynthesis MoaE protein KEGG: sil:SPO3633 molybdopterin converting factor, subunit 2; Molybdopterin-converting factor large subunit; Molybdenum cofactor biosynthesis protein E; Molybdopterin synthase subunit 2; MPT synthase subunit 2 YP_001534438.1 TIGRFAM: molybdopterin converting factor, subunit 1 PFAM: thiamineS protein KEGG: rsp:RSP_1072 putative molybdopterin MPT converting factor, subunit 1 protein; Neigbhorhood; Molybdopterin-converting factor small subunit; Molybdenum cofactor biosynthesis protein D; Molybdopterin synthase subunit 1; MPT synthase subunit 1 YP_001534439.1 TIGRFAM: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase PFAM: CDP-alcohol phosphatidyltransferase KEGG: rsh:Rsph17029_2734 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; PGP synthase; Phosphatidylglycerophosphate synthase YP_001534440.1 pfam00849 PseudoU_synth_2, COG0564 -Pseudouridylate synthases, 23S RNA-specific, TIGR00005 pseudouridine synthase, RluA family, good blast hit to swissprot.; rRNA pseudouridylate synthase A; rRNA-uridine isomerase A YP_001534441.1 PFAM: Lysine exporter protein (LYSE/YGGA) KEGG: sit:TM1040_0069 lysine exporter protein (LysE/YggA), good blast hit to R. denitrificans YP_001534442.1 PFAM: DSBA oxidoreductase KEGG: rde:RD1_0191 protein-disulfide isomerase, putative YP_001534443.1 KEGG: rde:RD1_0522 hypothetical protein YP_001534444.1 PFAM: cyclic nucleotide-binding KEGG: rsq:Rsph17025_3179 hypothetical protein YP_001534445.1 PFAM: sulfatase KEGG: rde:RD1_0531 arylsulfatase; Aryl-sulfate sulphohydrolase; AS YP_001534446.1 KEGG: rde:RD1_0530 nonspecific acid phosphatase YP_001534447.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5 KEGG: rde:RD1_0529 MoxR-like ATPase, putative YP_001534448.1 PFAM: protein of unknown function DUF58 KEGG: rde:RD1_0528 hypothetical protein, COG1721 YP_001534449.1 KEGG: rde:RD1_0527 hypothetical protein YP_001534450.1 PFAM:VWA von Willebrand factor type A domain KEGG: rde:RD1_0526 hypothetical protein,TMH YP_001534451.1 KEGG: rde:RD1_0525 hypothetical protein YP_001534452.1 KEGG: rde:RD1_0524 hypothetical protein YP_001534453.1 KEGG: sit:TM1040_2728 citrate synthase YP_001534454.1 PFAM: CoA-transferase family III PRK05398 formyl-coenzyme A transferase KEGG: sit:TM1040_2729 L-carnitine dehydratase/bile acid-inducible protein F; Formyl-CoA transferase YP_001534455.1 PFAM: protein of unknown function DUF112 transmembrane COG3333 - Uncharacterized protein conserved in bacteria YP_001534456.1 KEGG: rde:RD1_2947 hypothetical protein YP_001534457.1 COG3181 Uncharacterized protein conserved in bacteria KEGG: rde:RD1_2946 hypothetical protein YP_001534458.1 PFAM: response regulator receiver; transcriptional regulator domain protein KEGG: sit:TM1040_2733 two component transcriptional regulator, winged helix family COG0745 - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_001534459.1 PFAM:HATPase_c Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ,2CSK_N Two-component sensor kinase N-terminal KEGG: sit:TM1040_2734 periplasmic sensor signal transduction histidine kinase YP_001534460.1 KEGG: sil:SPO0189 putative iron(III) transport system substrate-binding protein. Annotation was derived from R. denitrificans YP_001534461.1 PFAM: extracellular solute-binding protein family 1 KEGG: rde:RD1_4122 sugar ABC transporter, periplasmic sugar-binding protein, putative; periplasmic sugar-binding protein, putative YP_001534462.1 PFAM: ABC transporter related; Transport-associated OB domain protein pfam00005,SMART: AAA ATPase KEGG: rde:RD1_4120 SN-glycerol-3-phosphate transport ATP-binding protein; ATP-binding protein (sn-glycerol-3-phosphate import ATP-binding protein ugpC) YP_001534463.1 PFAM: ABC transporter related; pfam00005, Transport-associated OB domain protein SMART: AAA ATPase KEGG: rde:RD1_4119 sugar ABC transporter, ATP-binding protein, putative; ATP-binding protein (sn-glycerol-3-phosphate import ATP-binding protein ugpC) YP_001534464.1 PFAM: binding-protein-dependent transport systems inner membrane component KEGG: rde:RD1_4118 sugar ABC transporter, permease protein, putative COG1175 - ABC-type sugar transport systems, permease components ,TMH; permease protein, putative (MSD) YP_001534465.1 PFAM: binding-protein-dependent transport systems inner membrane component KEGG: jan:Jann_4088 binding-protein-dependent transport systems inner membrane component COG0395 - ABC-type sugar transport system, permease component , TMH; permease protein, putative (MSD) YP_001534466.1 TMH YP_001534467.1 PFAM: Penicillinase repressor KEGG: rde:RD1_4115 transcriptional regulator, putative YP_001534468.1 PFAM: peptidase M56 BlaR1 KEGG: rde:RD1_4114 BlaR1 peptidase M56 domain protein; Motif HEXXH YP_001534470.1 LipoP1.0 KEGG: jan:Jann_1313 lipoprotein, putative YP_001534472.1 KEGG: smd:Smed_4297 alpha/beta hydrolase fold YP_001534473.1 KEGG: jan:Jann_1112 cupin 2 protein YP_001534474.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator KEGG: rde:RD1_3944 transcriptional regulatory protein, LacI family, putative; LacI family YP_001534475.1 PFAM: ABC transporter related; Transport-associated OB domain protein pfam00005,SMART: AAA ATPase KEGG: jan:Jann_4087 ABC transporter related; ATP-binding protein (sn-glycerol-3-phosphate import ATP-binding protein ugpC) YP_001534476.1 PFAM: binding-protein-dependent transport systems inner membrane component KEGG: jan:Jann_4088 binding-protein-dependent transport systems inner membrane component COG0395 - ABC-type sugar transport system, permease component ,TMH; permease protein, putative (MSD) YP_001534477.1 PFAM: binding-protein-dependent transport systems inner membrane component KEGG: jan:Jann_4089 binding-protein-dependent transport systems inner membrane component ;COG1175 - ABC-type sugar transport systems, permease components ,TMH; permease protein, putative (MSD) YP_001534478.1 PFAM: extracellular solute-binding protein family 1 COG1653 - ABC-type sugar transport system, periplasmic component YP_001534479.1 PFAM: HpcH/HpaI aldolase KEGG: mpt:Mpe_A0974 2-dehydro-3-deoxyglucarate aldolase ,COG3836 - 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase ,good sp-hit; KDGlucA; 5-keto-4-deoxy-D-glucarate aldolase; DDG aldolase; 2-dehydro-3-deoxygalactarate aldolase; 2-keto-3-deoxyglucarate aldolase YP_001534480.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001534481.1 PFAM: protein of unknown function DUF306 Meta and HslJ KEGG: sil:SPO2951 hypothetical protein COG3126 - Uncharacterized protein conserved in bacteria ;good GC-Frame Plot YP_001534483.1 PFAM: peptidase M15D vanX D-ala-D-ala dipeptidase KEGG: nmc:NMC1731 ddpX; putative D-alanyl-D-alanine dipeptidase YP_001534484.1 TIGR01121D-amino acid aminotransferase PFAM: aminotransferase class IV KEGG: jan:Jann_0363 aminotransferase, class IV ;good blast hit; DAAT; D-amino acid transaminase; D-amino acid aminotransferase; D-aspartate aminotransferase YP_001534485.1 PFAM: regulatory protein LysR; LysR substrate-binding KEGG: sil:SPO1110 transcriptional regulator, LysR family COG0583 - Transcriptional regulator; LysR family YP_001534486.1 PFAM: protein of unknown function DUF1445 KEGG: sil:SPO1111 hypothetical protein YP_001534487.1 PFAM: TRAP dicarboxylate transporter- DctP subunit KEGG: sil:SPO1112 TRAP transporter, periplasmic protein YP_001534488.1 KEGG: sil:SPO1113 TRAP transporter, transmembrane protein, putative,TMH YP_001534489.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit KEGG: sil:SPO1114 TRAP dicarboxylate transporter, DctM subunit,TMH YP_001534491.1 PFAM: TRAP dicarboxylate transporter- DctP subunit KEGG: csa:Csal_2479 TRAP dicarboxylate transporter, DctP subunit YP_001534492.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component KEGG: rsq:Rsph17025_2045 tripartite ATP-independent periplasmic transporter, DctQ component,TMH YP_001534493.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit KEGG: bbr:BB0721 hypothetical protein,TMH YP_001534494.1 TMH YP_001534495.1 PFAM: NapC/NirT cytochrome c domain protein KEGG: rsq:Rsph17025_3218 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001534496.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB) KEGG: rsq:Rsph17025_3219 polyferredoxin-like protein YP_001534497.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001534498.1 TIGRFAM: MauM/NapG family ferredoxin-type protein PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein KEGG: dar:Daro_3839 napG; MauM/NapG ferredoxin-type protein YP_001534499.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001534500.1 PFAM: NapD family protein KEGG: rsq:Rsph17025_3223 hypothetical protein YP_001534501.1 TIGRFAM: ferredoxin-type protein NapF PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein KEGG: sbl:Sbal_1481 ferredoxin-type protein NapF YP_001534502.1 PFAM: ApbE family lipoprotein KEGG: pde:Pden_2485 ApbE family lipoprotein YP_001534503.1 PFAM: cytochrome c class I KEGG: sil:SPOA0055 cytochrome c family protein YP_001534505.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein KEGG: rde:RD1_1574 cbiX; CbiX protein, putative YP_001534506.1 PFAM: cytochrome d1 heme region KEGG: sil:SPOA0228 nitrite reductase protein N YP_001534507.1 PFAM: Radical SAM domain protein SMART: Elongator protein 3/MiaB/NifB KEGG: sil:SPOA0227 nitrite reductase heme biosynthesis J protein YP_001534508.1 KEGG: sil:SPOA0226 nitrite reductase heme biosynthesis H protein, COG1522 - Transcriptional regulators YP_001534509.1 SMART: regulatory protein AsnC/Lrp family KEGG: rde:RD1_1570 nitrite reductase heme biosynthesis G YP_001534510.1 KEGG: sil:SPOA0224 nitrite reductase heme biosynthesis D/L protein, putative YP_001534511.1 PFAM: cytochrome d1 heme region KEGG: rde:RD1_1568 cytochrome cd1 YP_001534512.1 KEGG: sil:SPOA0222 cytochrome c55X , neighborhood; c55X YP_001534513.1 TIGRFAM: uroporphyrin-III C-methyltransferase PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase KEGG: sil:SPOA0221 nitrite reductase heme biosynthesis E protein rde:RD1_1566 nirE; uroporphyrin-III C-methyltransferase; Urogen III methylase YP_001534514.1 PFAM: cytochrome d1 heme region KEGG: rde:RD1_1565 nitrite reductase; Hydroxylamine reductase; Cytochrome oxidase; Cytochrome cd1 YP_001534515.1 PFAM: FMN-binding domain protein KEGG: pde:Pden_2486 FMN-binding domain protein YP_001534516.1 PFAM: NnrS family protein KEGG: sil:SPOA0219 NnrS, putative YP_001534517.1 KEGG: sil:SPOA0217 nitric oxide reductase, small subunit; NOR small subunit; Nitric oxide reductase cytochrome c subunit YP_001534518.1 KEGG: sil:SPOA0216 nitric oxide reductase, large subunit rde:RD1_1561 norB; nitric-oxide reductase subunit B YP_001534519.1 KEGG: sil:SPOA0215 nitric oxide reductase Q protein YP_001534520.1 PFAM: von Willebrand factor type A KEGG: sil:SPOA0214 nitric oxide reductase D protein pde:Pden_2481 von Willebrand factor, type A YP_001534521.1 PFAM: cytochrome c oxidase subunit III KEGG:rde:RD1_1558 norE; NorE protein YP_001534523.1 PFAM: cyclic nucleotide-binding KEGG: sil:SPOA0323 cyclic nucleotide-binding protein; similar to DnrD YP_001534524.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_001534525.1 PFAM: cyclic nucleotide-binding SMART: regulatory protein Crp KEGG: sil:SPOA0323 cyclic nucleotide-binding protein YP_001534527.1 KEGG:rde:RD1_1546 nosR; nitrous-oxide reductase regulatory protein NosR PFAM: FMN-binding domain protein YP_001534528.1 reduces nitrous oxide to nitrogen YP_001534529.1 PFAM: periplasmic copper-binding NosD SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis KEGG: rde:RD1_1548 nosD; nitrous oxide maturation protein; pde:Pden_4218 periplasmic copper-binding YP_001534530.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: rde:RD1_1549 nosF; copper transport ATP-binding protein NosF YP_001534531.1 KEGG: pde:Pden_4216 nitrous oxide maturation protein NosY YP_001534532.1 PFAM: NosL family protein KEGG: pde:Pden_4215 NosL family protein YP_001534533.1 PFAM: ApbE family lipoprotein KEGG: pde:Pden_4214 ApbE family lipoprotein rde:RD1_1552 nosX; nitrous-oxide reductase protein NosX YP_001534534.1 PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein KEGG: jan:Jann_2601 protein of unknown function DUF861, cupin_3 YP_001534535.1 PFAM: Endoribonuclease L-PSP KEGG: rde:RD1_1044 endoribonuclease L-PSP family protein, putative YP_001534536.1 TIGRFAM: uracil-xanthine permease PFAM: Xanthine/uracil/vitamin C permease KEGG: rde:RD1_4153 xanthine/uracil permease, putative,10xTHM; Uracil transporter YP_001534537.1 PFAM: Ureidoglycolate hydrolase KEGG: rsh:Rsph17029_0204 ureidoglycolate hydrolase YP_001534538.1 PFAM: polysaccharide deacetylase; pfam09349, OHCU_decarbox, OHCU decarboxylase. KEGG: jan:Jann_2608 polysaccharide deacetylase YP_001534539.1 TIGRFAM: Hydroxyisourate hydrolase PFAM: Transthyretin KEGG: rde:RD1_4150 hypothetical protein YP_001534540.1 PFAM: regulatory protein LysR; LysR substrate-binding ;HTH_1 pfam00126 Bacterial regulatory helix-turn-helix protein, lysR family KEGG: rde:RD1_4149 transcriptional regulator, LysR family, putative; LysR family YP_001534541.1 PFAM: protein of unknown function DUF989 KEGG: rde:RD1_4148 hypothetical protein YP_001534544.1 PFAM: phospholipase D/Transphosphatidylase KEGG: bpe:BP3092 putative phospholipase D protein YP_001534545.1 KEGG: mpt:Mpe_A0912 putative sulfite oxidase cytochrome subunit YP_001534546.1 PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain KEGG: mpt:Mpe_A0911 putative sulfite oxidase;nwi:Nwi_2988 oxidoreductase, molybdopterin binding YP_001534547.1 PFAM: integrase family protein KEGG: nwi:Nwi_0831 phage integrase YP_001534548.1 KEGG: rru:Rru_A0340 CRISPR-associated helicase Cas3, core TIGRFAM: CRISPR-associated helicase Cas3 PFAM: helicase domain protein SMART: DEAD-like helicases YP_001534549.1 TIGRFAM: CRISPR-associated protein, Cse1 family KEGG: rru:Rru_A0341 hypothetical protein;aeh:Mlg_0954 CRISPR-associated protein, CSE1 family YP_001534551.1 TIGRFAM: CRISPR-associated protein, Cse4 family PFAM: CRISPR-associated protein CT1975 KEGG: rru:Rru_A0344 CRISPR-associated CT1975 family protein; Cse4 family YP_001534552.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5 KEGG: rru:Rru_A0345 CRISPR-associated CT1976 family protein YP_001534553.1 PFAM: CRISPR-associated protein CT1974 KEGG: rru:Rru_A0346 CRISPR-associated CT1974 family protein TIGR01907 CRISPR-associated protein, Cse3 family; Cse3 family YP_001534554.1 TIGRFAM: CRISPR-associated protein Cas1 KEGG: mca:MCA0930 CRISPR-associated protein Cas1 YP_001534555.1 TIGRFAM: CRISPR-associated protein Cas2 KEGG: rru:Rru_A0348 CRISPR-associated protein, Cas2 YP_001534557.1 TIGRFAM: DNA binding domain, excisionase family KEGG: she:Shewmr4_2783 hypothetical protein YP_001534558.1 PFAM: integrase family protein KEGG: mpt:Mpe_A3816 site-specific recombinase XerD-like protein YP_001534562.1 PFAM: diaminopimelate epimerase KEGG: sil:SPO0278 diaminopimelate epimerase; DAP epimerase YP_001534563.1 KEGG: pde:Pden_0396 MiaB-like tRNA modifying enzyme TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme PFAM: Radical SAM domain protein; Protein of unknown function UPF0004 SMART: Elongator protein 3/MiaB/NifB YP_001534565.1 rsp:RSP_1458 putative DNA repair enzyme YP_001534566.1 KEGG: sil:SPO3807 hypothetical protein YP_001534567.1 PFAM: NLP/P60 protein KEGG: jan:Jann_0105 NLP/P60 YP_001534568.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein KEGG: sil:SPO3717 cytosol aminopeptidase family protein; (LAP) (Leucyl aminopeptidase) YP_001534570.1 PFAM: carbonic anhydrase KEGG: sil:SPO3715 carbonic anhydrase, putative ; rde:RD1_0312 cynT; carbonate anhydratase YP_001534571.1 PFAM: protein of unknown function DUF897 KEGG: jan:Jann_0109 protein of unknown function DUF897 YP_001534572.1 KEGG: jan:Jann_0110 hypothetical protein YP_001534573.1 KEGG: sil:SPO3714 hypothetical protein YP_001534574.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001534575.1 PFAM: glycosyl transferase group 1 KEGG: pde:Pden_2773 glycosyl transferase, group 1;rde:RD1_3309 lpcC;lipopolysaccharide core biosynthesis mannosyltransferase YP_001534576.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407 KEGG: sit:TM1040_2114 protein of unknown function DUF404; DUF407 YP_001534577.1 PFAM: protein of unknown function DUF403 KEGG: jan:Jann_2677 protein of unknown function DUF403 YP_001534578.1 PFAM: transglutaminase domain protein; transglutaminase domain protein KEGG: hne:HNE_2679 transglutaminase family protein YP_001534579.1 PFAM: 20S proteasome A and B subunits KEGG: rde:RD1_4009 proteasome-type protease, putative YP_001534580.1 KEGG: rsq:Rsph17025_2599 ATPase, FliI/YscN family TIGRFAM: ATPase, FliI/YscN family PFAM: H+transporting two-sector ATPase alpha/beta subunit central region YP_001534581.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_001534582.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001534583.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001534584.1 Swissprot: P74931 Flagellar biosynthetic protein fliQ PFAM: export protein FliQ family 3 KEGG: pde:Pden_2113 export protein FliQ, family 3 YP_001534585.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Rhodobacter sphaeroides has 2 copies of this and other flagella genes YP_001534586.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella YP_001534587.1 required for the assembly of the flagellar basal body P-ring YP_001534588.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001534589.1 PFAM: flagellar basal body-associated protein FliL YP_001534590.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001534591.1 PFAM: type III secretion system inner membrane R protein KEGG: jan:Jann_4187 flagellar biosynthetic protein FliR YP_001534592.1 membrane protein involved in the flagellar export apparatus YP_001534593.1 KEGG: rsh:Rsph17029_2977 hypothetical protein YP_001534594.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001534595.1 KEGG: rsh:Rsph17029_2975 hypothetical protein YP_001534596.1 KEGG: rde:RD1_0271 hypothetical protein YP_001534597.1 PFAM: flagellar basal body-associated protein FliL KEGG: rsh:Rsph17029_2973 flagellar basal body-associated protein FliL YP_001534598.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001534599.1 COG: FliH, Flagellar biosynthesis/type III secretory pathway protein PRK: fliH, flagellar assembly protein H KEGG: rsh:Rsph17029_2971 putative flagellar biosynthesis/type III secretory pathway protein YP_001534600.1 Swissprot: Q03593 Flagellar motor switch protein fliN COG: Flagellar motor switch/type III secretory pathway protein YP_001534601.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001534602.1 PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein KEGG: rpe:RPE_1300 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; beta subunit YP_001534603.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F KEGG: sit:TM1040_0389 L-carnitine dehydratase/bile acid-inducible protein F YP_001534605.1 PFAM: protein of unknown function DUF59 KEGG: rde:RD1_2906 hypothetical protein YP_001534606.1 KEGG: rde:RD1_2905 hypothetical protein YP_001534609.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001534610.1 PFAM: cytochrome c1 KEGG: rde:RD1_0565 cytochrome c1 YP_001534611.1 PFAM: Cytochrome b/b6 domain KEGG: jan:Jann_0326 cytochrome b/b6-like YP_001534612.1 TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit PFAM: Rieske [2Fe-2S] domain protein KEGG: sit:TM1040_2814 ubiquinol-cytochrome c reductase, iron-sulfur subunit; iron-sulfur subunit YP_001534613.1 PFAM: Glutathione S-transferase domain KEGG: rsp:RSP_1397 glutathione S-transferase YP_001534614.1 KEGG: rsq:Rsph17025_2805 hypothetical protein YP_001534615.1 PFAM: nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase KEGG: syn:sll0656 extracellular nuclease YP_001534616.1 TIGR00129 formate dehydrogenase family accessory protein FdhD PFAM: formate dehydrogenase subunit FdhD KEGG: sil:SPO0306 formate dehydrogenase accessory protein FdhD YP_001534617.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001534618.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein domain I and II; MoeA domain protein domain IV KEGG: sil:SPO0310 molybdopterin biosynthesis protein MoeA rde:RD1_3407 moeA; molybdopterin biosynthesis protein, putative YP_001534619.1 PFAM: Thioredoxin domain KEGG: rde:RD1_0213 thioredoxin, putative YP_001534620.1 PFAM: cytochrome c biogenesis protein transmembrane region KEGG: rde:RD1_0214 cytochrome c biogenesis protein YP_001534621.1 PFAM: protein of unknown function DUF6 transmembrane KEGG: sit:TM1040_2802 protein of unknown function DUF6, transmembrane ; rde:RD1_0601 hypothetical protein ; TMH; 2x DUF6 YP_001534622.1 PFAM: histone family protein DNA-binding protein KEGG: rde:RD1_0603 DNA-binding protein HU YP_001534623.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001534624.1 KEGG: sil:SPO3747 hypothetical protein YP_001534625.1 KEGG: jan:Jann_0273 NAD-dependent epimerase/dehydratase rde:RD1_0614 hypothetical protein YP_001534628.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001534629.1 PFAM: Polyprenyl synthetase KEGG: rde:RD1_0549 ispA; geranyltranstransferase; FPP synthase; Farnesyl-diphosphate synthase YP_001534630.1 PFAM: histone deacetylase superfamily KEGG: rsp:RSP_1137 histone deacetylase family protein; Exonuclease VII small subunit YP_001534631.1 PFAM: histone deacetylase superfamily KEGG: rsp:RSP_1137 histone deacetylase family protein YP_001534632.1 KEGG: mlo:mlr2044 hypothetical protein YP_001534633.1 Swissprot: Protein petR PFAM: response regulator receiver; transcriptional regulator domain protein YP_001534634.1 PFAM: regulatory protein MarR KEGG: rde:RD1_0552 transcriptional regulator, MarR family; MarR family YP_001534635.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001534636.1 KEGG: atc:AGR_L_2414 hypothetical protein YP_001534637.1 REFSEQ: ref|ZP_01012112.1 membrane protein, putative [Rhodobacterale bacterium] YP_001534638.1 KEGG: sil:SPO2058 hypothetical protein YP_001534639.1 PFAM: integral membrane protein DUF6 KEGG: jan:Jann_3870 protein of unknown function DUF6, transmembrane; transmembrane YP_001534641.1 TIGRFAM: iron-sulfur cluster binding protein, putative PFAM: domain of unknown function DUF1730 KEGG: jan:Jann_0274 4Fe-4S ferredoxin, iron-sulfur binding; (protein of unknown function DUF1730) YP_001534642.1 PFAM: Glutathione S-transferase domain KEGG: rsq:Rsph17025_2783 glutathione S-transferase, N-terminal domain YP_001534643.1 TIGRFAM: monofunctional biosynthetic peptidoglycan transglycosylase PFAM: glycosyl transferase family 51 KEGG: rsh:Rsph17029_2806 monofunctional biosynthetic peptidoglycan transglycosylase YP_001534644.1 COG: RssA, Predicted esterase of the alpha-beta hydrolase superfamily PFAM: Patatin-like phospholipase YP_001534645.1 TIGRFAM: radical SAM enzyme, Cfr family PFAM: Radical SAM domain protein KEGG: rsq:Rsph17025_0041 radical SAM enzyme, Cfr family; Cfr family YP_001534646.1 KEGG: jan:Jann_2393 hypothetical protein YP_001534647.1 KEGG: rsh:Rsph17029_0081 hypothetical protein YP_001534648.1 KEGG: rde:RD1_0193 hypothetical protein YP_001534650.1 KEGG: sil:SPO3353 phosphoserine phosphatase TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like) PFAM: Haloacid dehalogenase domain protein hydrolase YP_001534651.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_001534652.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001534653.1 PFAM: metallophosphoesterase KEGG: rsq:Rsph17025_0011 metallophosphoesterase YP_001534654.1 KEGG: rde:RD1_1295 hypothetical protein YP_001534655.1 PFAM: CreA family protein KEGG: rsh:Rsph17029_1167 CreA family protein YP_001534656.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator KEGG: sil:SPO3684 transcriptional regulator, LacI family; LacI family YP_001534657.1 PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: jan:Jann_1164 transcriptional regulator, GntR family; GntR family YP_001534658.1 PFAM: FAD binding domain, FAD linked oxidases KEGG: jan:Jann_1163 D-lactate dehydrogenase (cytochrome) YP_001534659.1 Swissprot: Q56YA5 Serine--glyoxylate aminotransferase PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase KEGG: jan:Jann_1162 aminotransferase, class V; Serine--pyruvate aminotransferase; AGT; Alanine--glyoxylate aminotransferase YP_001534660.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit PFAM: TRAP dicarboxylate transporter- DctP subunit KEGG: pmu:PM1651 hypothetical E.coli; precursor YP_001534661.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component YP_001534662.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001534663.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001534664.1 PFAM: CoA-transferase family III PRK: formyl-coenzyme A transferase YP_001534665.1 catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA YP_001534666.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein KEGG: rde:RD1_0357 hybrid sensory histidine kinase, putative YP_001534667.1 PFAM: protein of unknown function DUF328 KEGG: sil:SPO0106 hypothetical protein YP_001534668.1 KEGG: rde:RD1_0359 ATP-dependent DNA helicase RecQ TIGRFAM: ATP-dependent DNA helicase RecQ PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding SMART: DEAD-like helicases YP_001534669.1 PFAM: protein of unknown function YGGT KEGG: sil:SPO0122 YGGT family protein; transmembrane YP_001534670.1 KEGG: sit:TM1040_2661 hypothetical protein YP_001534671.1 PFAM: major facilitator superfamily MFS_1 KEGG: jan:Jann_0343 major facilitator superfamily MFS_1 YP_001534672.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001534673.1 KEGG: rsq:Rsph17025_0022 hypothetical protein YP_001534674.1 TIGRFAM: conserved hypothetical integral membrane protein PFAM: protein of unknown function DUF165 KEGG: sit:TM1040_2665 protein of unknown function DUF165 YP_001534675.1 TIGRFAM: alpha-L-glutamate ligase, RimK family PFAM: RimK domain protein ATP-grasp KEGG: rde:RD1_2956 ribosomal protein S6 modification protein (C terminal domain) YP_001534676.1 PFAM: Class I peptide chain release factor KEGG: rde:RD1_0366 peptidyl-tRNA hydrolase, putative YP_001534677.1 PFAM: aminotransferase class-III KEGG: sil:SPOA0354 aminotransferase, class III YP_001534678.1 PFAM: aminoglycoside phosphotransferase YP_001534679.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001534680.1 KEGG: sil:SPO0094 sensory box sensor histidine kinase/response regulator TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein; PAC repeat-containing protein YP_001534681.1 KEGG: jan:Jann_0014 nicotinamidase YP_001534682.1 PFAM: Rhodanese domain protein KEGG: pde:Pden_0850 rhodanese domain protein YP_001534683.1 PRK tRNA 2-selenouridine synthase YP_001534684.1 TIGRFAM: selenium donor protein PFAM: AIR synthase related protein domain protein KEGG: sil:SPO2899 selenide,water dikinase, putative; (Selenophosphate synthetase) (Selenium donor protein) YP_001534685.1 KEGG: bbt:BBta_2726 putative membrane protein of unknown function YP_001534686.1 KEGG: jan:Jann_0255 hypothetical protein YP_001534687.1 PFAM: Predicted permease KEGG: rsq:Rsph17025_3021 protein of unknown function DUF214; protein of unknown function DUF214 YP_001534688.1 PFAM: FtsE, Predicted ATPase involved in cell division YP_001534689.1 negatively supercoils closed circular double-stranded DNA YP_001534690.1 PFAM: Transposase KEGG: mag:amb0646 insertion element ISR1 hypothetical 10 kDa protein A3 YP_001534691.1 PFAM: Integrase catalytic region KEGG: bbt:BBta_7691 integrase, catalytic domain YP_001534692.1 PFAM: protein of unknown function DUF1217 KEGG: sil:SPO3456 flagellar protein, putative YP_001534693.1 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001534694.1 acts as an activator of flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagellum YP_001534695.1 PFAM: flagellin domain protein KEGG: jan:Jann_4203 flagellin-like YP_001534697.1 PRK: flgJ, peptidoglycan hydrolase KEGG: sit:TM1040_2976 flagellar protein FlgJ, putative YP_001534698.1 PFAM: flagellar hook-length control protein YP_001534699.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Rhodobacter sphaeroides has 2 copies of many flagellar genes; the Rhodobacter protein in this cluster is associated with a set of flagellar genes acquired by lateral gene transfer; these genes are not normally expressed YP_001534700.1 PFAM: Phosphotransferase enzyme family Genbank: gb|ABF65711.1 aminoglycoside phosphotransferase (Silicibacter sp.) YP_001534701.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase PFAM: ABC-1 domain protein KEGG: rde:RD1_0202 ubiquinone biosynthesis protein UbiB YP_001534702.1 TIGRFAM: ubiquinone biosynthesis methyltransferase PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 KEGG: jan:Jann_4209 ubiquinone/menaquinone biosynthesis methyltransferases PMID: 9045837 YP_001534703.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001534704.1 PFAM: Enoyl-CoA hydratase/isomerase KEGG: rsh:Rsph17029_0009 enoyl-CoA hydratase/isomerase YP_001534705.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001534706.1 PFAM: Rhodanese Homology Domain superfamily, subgroup 1 COG: PspE, Rhodanese-related sulfurtransferase YP_001534707.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001534708.1 binds the polymerase to DNA and acts as a sliding clamp YP_001534709.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001534710.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001534711.1 PFAM: Putative flagellar hook-associated protein 3 (HAP3) KEGG: sil:SPO0194 flagellar hook-associated protein FlgL family protein YP_001534712.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001534713.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein Swissprot: Flagellar hook protein flgE YP_001534714.1 PRK: motB, flagellar motor protein MotB COG: MotB, Flagellar motor protein REFSEQ: chemotaxis protein MotB YP_001534715.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein KEGG: rde:RD1_2329 outer membrane protein, putative YP_001534716.1 PFAM: protein of unknown function DUF490 KEGG: jan:Jann_0244 protein of unknown function DUF490 YP_001534717.1 PFAM: Rhomboid family protein KEGG: jan:Jann_4233 rhomboid-like protein YP_001534718.1 TIGRFAM: eight transmembrane protein EpsH; Methanolan biosynthesis EpsI KEGG: jan:Jann_4271 hypothetical protein YP_001534719.1 PFAM: Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein SMART: Tetratricopeptide domain protein KEGG: jan:Jann_4236 tetratricopeptide TPR_2 YP_001534720.1 PFAM: sugar transferase KEGG: rde:RD1_B0024 bacterial sugar transferase; Galactosyl-P-P-undecaprenol synthetase YP_001534721.1 REFSEQ: general secretion pathway protein A [Roseobacter denitrificans] COG: Type II secretory pathway, component ExeA (predicted ATPase) SMART: AAA ATPase KEGG: jan:Jann_4238 ATPase; component ExeA (predicted ATPase) YP_001534722.1 TIGRFAM: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily PFAM: lipopolysaccharide biosynthesis protein KEGG: jan:Jann_4239 lipopolysaccharide biosynthesis; PEP-CTERM locus subfamily YP_001534723.1 KEGG: jan:Jann_4240 ATPases involved in chromosome partitioning-like YP_001534724.1 PFAM: metallophosphoesterase KEGG: jan:Jann_3688 metallophosphoesterase YP_001534725.1 PFAM: beta-lactamase domain protein KEGG: rde:RD1_3791 metallo-beta-lactamase family protein, putative YP_001534726.1 PFAM: Antibiotic biosynthesis monooxygenase KEGG: rde:RD1_3790 hypothetical protein YP_001534727.1 PFAM: isocitrate/isopropylmalate dehydrogenase KEGG: rde:RD1_3789 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase YP_001534728.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; homoserine dehydrogenase NAD-binding KEGG: rde:RD1_3788 probable NADH-dependent dyhydrogenase YP_001534729.1 PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit KEGG: cps:CPS_1266 putative C4-dicarboxylate transporter family protein, DctM subunit YP_001534730.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component KEGG: maq:Maqu_0086 tripartite ATP-independent periplasmic transporter, DctQ component YP_001534731.1 PFAM: TRAP dicarboxylate transporter- DctP subunit KEGG: cps:CPS_1264 extracellular solute-binding protein, family 7; precursor YP_001534732.1 KEGG: nha:Nham_4013 ISSpo6, transposase OrfB; transposase OrfB YP_001534733.1 KEGG: nha:Nham_4014 ISSpo6, transposase orf A; transposase OrfA YP_001534734.1 KEGG: rde:RD1_0737 3-demethylubiquinone-9 3-methyltransferase TIGRFAM: ubiquinone biosynthesis O-methyltransferase PFAM: Methyltransferase type 11; Methyltransferase type 12; (3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) YP_001534735.1 KEGG: rde:RD1_0738 hypothetical protein YP_001534736.1 KEGG: rsp:RSP_0230 neutral zinc metallopeptidase CD: Zinc-dependent metalloprotease, serralysin_like subfamily YP_001534737.1 PFAM: AMP-dependent synthetase and ligase KEGG: rde:RD1_1106 putative long chain fatty acid acyl-CoA ligase YP_001534738.1 KEGG: mpt:Mpe_A3536 hypothetical protein YP_001534739.1 PFAM: DSBA oxidoreductase YP_001534740.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein KEGG: mes:Meso_4112 ErfK/YbiS/YcfS/YnhG YP_001534741.1 KEGG: mag:amb3382 thiol:disulfide interchange protein DsbD 1 precursor YP_001534742.1 PFAM: TPR repeat-containing protein SMART: Tetratricopeptide domain protein KEGG: ret:RHE_CH01289 cytochrome-C-type biogenesis protein YP_001534743.1 PFAM: cytochrome C biogenesis protein KEGG: rsh:Rsph17029_1291 cytochrome c biogenesis protein YP_001534744.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein KEGG: mes:Meso_3362 periplasmic protein thiol--disulphide oxidoreductase DsbE YP_001534745.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF PFAM: cytochrome c assembly protein KEGG: mag:amb4200 cytochrome c biogenesis factor YP_001534746.1 PFAM: protein of unknown function DUF55 YP_001534747.1 PFAM: YCII-related KEGG: rde:RD1_0468 YCII-related domain protein YP_001534748.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001534749.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001534750.1 PFAM: Uroporphyrinogen III synthase HEM4 KEGG: rsq:Rsph17025_2913 uroporphyrinogen III synthase HEM4; Hydroxymethylbilane hydrolyase [cyclizing]; Uroporphyrinogen-III cosynthetase; UROS YP_001534751.1 KEGG: jan:Jann_4082 hypothetical protein YP_001534752.1 PFAM: HemY domain protein YP_001534753.1 PFAM: Amidase KEGG: rsq:Rsph17025_3870 2-alkenal reductase YP_001534754.1 TIGRFAM: glycerol kinase PFAM: carbohydrate kinase FGGY KEGG: rde:RD1_2883 glycerol kinase; GK; Glycerokinase; ATP:glycerol 3-phosphotransferase YP_001534755.1 Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides YP_001534756.1 no hits to other proteins YP_001534757.1 TIGRFAM: RNA polymerase sigma-70 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; (sigma-70 factor family, ECF subfamily) YP_001534758.1 no significant BLAST hits, GC frame plot ok YP_001534759.1 KEGG: sil:SPO3859 hypothetical protein YP_001534760.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001534761.1 PFAM: glycosyl transferase family 8 KEGG: rde:RD1_0464 lipopolysaccharide 1,3-galactosyltransferase, putative; 3-galactosyltransferase, (Lipopolysaccharide 3-alpha-galactosyltransferase) YP_001534762.1 no hits to other proteins YP_001534763.1 PFAM: HD domain KEGG: sit:TM1040_2836 metal dependent phosphohydrolase YP_001534764.1 PFAM: response regulator receiver KEGG: sil:SPO3865 photosynthetic apparatus regulatory protein RegA; Response regulator PrrA YP_001534765.1 PFAM: electron transport protein SCO1/SenC KEGG: sit:TM1040_2839 electron transport protein SCO1/SenC YP_001534766.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein KEGG: sil:SPO3867 sensor histidine kinase RegB; Protein PrrB YP_001534767.1 TIGRFAM: PAS domain S-box REFSEQ: PAS domain containing protein YP_001534768.1 PFAM: protein of unknown function UPF0079 KEGG: rsq:Rsph17025_2955 protein of unknown function UPF0079 YP_001534769.1 PFAM: aminoglycoside phosphotransferase KEGG: rsh:Rsph17029_0175 aminoglycoside phosphotransferase YP_001534770.1 PFAM: Nucleotidyl transferase KEGG: pde:Pden_2796 nucleotidyl transferase YP_001534771.1 TIGRFAM: Double-strand break repair protein AddB KEGG: rsq:Rsph17025_2952 RecB family exonuclease-like protein PMID: 15547262 YP_001534772.1 TIGRFAM: Double-strand break repair helicase AddA PFAM: UvrD/REP helicase KEGG: rsp:RSP_1527 helicase, UvrD/Rep family PMID: 15547262 YP_001534773.1 TIGRFAM: thioredoxin PFAM: Thioredoxin domain KEGG: rde:RD1_0451 thioredoxin; Trx YP_001534774.1 heat shock protein involved in degradation of misfolded proteins YP_001534775.1 heat shock protein involved in degradation of misfolded proteins YP_001534776.1 PFAM: major facilitator superfamily MFS_1 KEGG: sit:TM1040_0930 major facilitator superfamily MFS_1 YP_001534777.1 PFAM: Smr protein/MutS2 KEGG: rde:RD1_0446 Smr domain protein YP_001534778.1 PFAM: MltA domain protein; 3D domain protein KEGG: jan:Jann_0190 MltA YP_001534779.1 PFAM: import inner membrane translocase subunit Tim44 KEGG: jan:Jann_0191 import inner membrane translocase, subunit Tim44; subunit Tim44 YP_001534780.1 PFAM: FxsA cytoplasmic membrane protein KEGG: sil:SPO3887 FxsA YP_001534781.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001534782.1 KEGG: rsq:Rsph17025_2673 DNA polymerase III, epsilon subunit TIGRFAM: DNA polymerase III, epsilon subunit PFAM: Exonuclease RNase T and DNA polymerase III SMART: Exonuclease YP_001534783.1 KEGG: pde:Pden_2814 dephospho-CoA kinase TIGRFAM: dephospho-CoA kinase PFAM: Dephospho-CoA kinase; Dephosphocoenzyme A kinase YP_001534784.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001534785.1 TIGRFAM: maf protein PFAM: Maf family protein KEGG: sil:SPO3892 Maf YP_001534786.1 PFAM: Uncharacterized protein family (UPF0093) Swissprot: UPF0093 membrane protein YP_001534787.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001534788.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001534789.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001534790.1 TIGRFAM: methyltransferase GidB PFAM: glucose inhibited division protein KEGG: acr:Acry_2405 methyltransferase GidB; Glucose-inhibited division protein B YP_001534791.1 PFAM: ParA family ATPase YP_001534792.1 TIGRFAM: parB-like partition protein PFAM: ParB domain protein nuclease KEGG: rsp:RSP_1225 ParB-like partition protein YP_001534793.1 PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454 YP_001534794.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001534795.1 PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP YP_001534796.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001534797.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001534798.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001534799.1 PFAM: GrpE protein KEGG: jan:Jann_0208 GrpE protein; HSP-70 cofactor YP_001534800.1 This protein performs the mismatch recognition step during the DNA repair process YP_001534801.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001534802.1 TIGRFAM: peptide methionine sulfoxide reductase PFAM: Methionine sulfoxide reductase A KEGG: rde:RD1_0419 methionine-S-sulfoxide reductase, putative YP_001534803.1 REFSEQ: putative branched-chain amino acid aminotransferase YP_001534804.1 PFAM: peptidase M48 Ste24p YP_001534805.1 PFAM: protein of unknown function DUF898 transmembrane KEGG: sme:SMc00782 hypothetical protein YP_001534806.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001534807.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_001534808.1 Catalyzes the cycloisomerization of cis,cis-muconate YP_001534809.1 PFAM: protein of unknown function DUF849 KEGG: jan:Jann_4165 protein of unknown function DUF849 YP_001534810.1 KEGG: bmb:BruAb2_0580 protocatechuate 3,4-dioxygenase, alpha subunit TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit PFAM: intradiol ring-cleavage dioxygenase; (3,4-PCD) YP_001534811.1 TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit PFAM: intradiol ring-cleavage dioxygenase KEGG: sit:TM1040_0558 protocatechuate 3,4-dioxygenase, beta subunit; (3,4-PCD) YP_001534812.1 TIGRFAM: 4-carboxymuconolactone decarboxylase PFAM: Carboxymuconolactone decarboxylase KEGG: sit:TM1040_0559 4-carboxymuconolactone decarboxylase; CMD YP_001534813.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_001534814.1 PFAM: regulatory protein LysR KEGG: pde:Pden_2664 putative transcriptional regulator, ModE family PMID 8550508 YP_001534815.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein PFAM: extracellular solute-binding protein family 1 KEGG: rsp:RSP_3871 ABC molybdate transporter, periplasmic binding protein ModA YP_001534816.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001534817.1 KEGG: sil:SPO0697 molybdate ABC transporter, ATP-binding protein TIGRFAM: molybdate ABC transporter, ATPase subunit PFAM: ABC transporter related; TOBE domain protein SMART: AAA ATPase YP_001534818.1 PFAM: Hpt domain protein KEGG: sit:TM1040_2886 Hpt protein YP_001534819.1 PFAM: response regulator receiver; Stage II sporulation E family protein SMART: protein phosphatase 2C domain protein KEGG: rde:RD1_0413 response regulator YP_001534820.1 PFAM: NUDIX hydrolase KEGG: rsp:RSP_1208 NUDIX hydrolase YP_001534821.1 PFAM: Hsp33 protein KEGG: jan:Jann_0079 HSP33 protein; HSP33 YP_001534822.1 PFAM: NUDIX hydrolase KEGG: sit:TM1040_2890 NUDIX hydrolase YP_001534823.1 PFAM: Polynucleotide adenylyltransferase region KEGG: sil:SPO0026 polyA polymerase family protein; tRNA-NT; tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl-transferase; tRNA nucleotidyltransferase YP_001534824.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: sil:SPO0027 ABC transporter, transmembrane ATP-binding protein YP_001534825.1 PFAM: ABC transporter transmembrane region; ABC transporter related SMART: AAA ATPase KEGG: rsq:Rsph17025_2641 ABC transporter related YP_001534826.1 PFAM: (Uracil-5)-methyltransferase KEGG: sil:SPO0029 23S rRNA (uracil-5-)-methyltransferase RumA YP_001534827.1 PFAM: Ion transport protein KEGG: rsq:Rsph17025_2848 ion transport protein REFSEQ: ref|ZP_01055369.1 voltage-gated sodium channel YP_001534828.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein KEGG: sil:SPO0031 ErfK/YbiS/YcfS/YnhG family protein PMID: 17098896 YP_001534829.1 PFAM: SCP-like extracellular KEGG: rsh:Rsph17029_2861 allergen V5/TPX-1 family protein YP_001534830.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein KEGG: rde:RD1_0402 ErfK/YbiS/YcfS/YnhG family protein PMID: 17098896 YP_001534832.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001534833.1 KEGG: jan:Jann_0294 hypothetical protein PFAM Methyltransferase domain PMID: 17098896 YP_001534834.1 KEGG: sil:SPO0071 competence protein F, putative TIGR00201 comF family protein PMID 17098896 YP_001534835.1 KEGG: rde:RD1_0121 spheroidene monooxygenase PMID: 17098896 YP_001534836.1 involved in chelation of magnesium into protoporphyrin IX; involved in bacteriochlorophyll biosynthesis; part of a complex with BchI, BchD, and BchH YP_001534837.1 involved in chelation of magnesium into protoporphyrin IX; involved in bacteriochlorophyll biosynthesis; part of a complex with BchI, BchD, and BchH YP_001534838.1 PFAM: alpha/beta hydrolase fold; Thioesterase; phospholipase/Carboxylesterase KEGG: rsh:Rsph17029_1918 alpha/beta hydrolase fold Swissprot: P26174 Magnesium-chelatase 30 kDa subunit PMID: 17098896; Mg-protoporphyrin IX chelatase YP_001534839.1 PFAM: regulatory protein MarR KEGG: rsh:Rsph17029_2853 transcriptional regulator, MarR family; MarR family YP_001534840.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase KEGG: sil:SPO0069 hydrolase, carbon-nitrogen family YP_001534841.1 TIGRFAM: glutaredoxin 3 PFAM: glutaredoxin KEGG: sil:SPO0070 glutaredoxin; Grx3 YP_001534842.1 TIGRFAM: Zeta-phytoene desaturase PFAM: amine oxidase; FAD dependent oxidoreductase KEGG: rde:RD1_0120 phytoene dehydrogenase PMID: 17098896; Phytoene desaturase YP_001534843.1 PFAM: Squalene/phytoene synthase KEGG: rde:RD1_0119 phytoene synthase PMID: 17098896 YP_001534844.1 PFAM: TspO/MBR family protein KEGG: jan:Jann_0035 TspO and MBR like proteins PMID: 17098896; 10648776 YP_001534845.1 KEGG: rsh:Rsph17029_2919 hypothetical protein YP_001534846.1 PFAM: hydroxyneurosporene synthase KEGG: rde:RD1_0116 hydroxyneurosporene dehydrogenase PMID: 17098896 YP_001534847.1 TIGRFAM: Zeta-phytoene desaturase PFAM: amine oxidase; FAD dependent oxidoreductase KEGG: jan:Jann_0183 amine oxidase Swissprot: P17059 PMID: 17098896 YP_001534848.1 PFAM: Polyprenyl synthetase KEGG: jan:Jann_0182 polyprenyl synthetase COG0142 PMID: 17098896; Farnesyltranstransferase; GGPP synthetase YP_001534849.1 PFAM: O-methyltransferase family 2; Methyltransferase type 12 KEGG: jan:Jann_0181 O-methyltransferase, family 2 PMID: 17098896; O-methylase YP_001534850.1 TIGRFAM: chlorophyll synthesis pathway, BchC PFAM: Alcohol dehydrogenase GroES domain protein KEGG: jan:Jann_0180 chlorophyll synthesis pathway, BchC PMID: 17098896 YP_001534851.1 KEGG: jan:Jann_0179 chlorophyllide reductase iron protein subunit X TIGRFAM: chlorophyllide reductase iron protein subunit X PFAM: NifH/frxC-family protein PMID: 17098896; 10648776; 8468299 YP_001534852.1 TIGRFAM: chlorophyllide reductase subunit Y KEGG: jan:Jann_0178 chlorophyllide reductase subunit Y PMID: 17098896; 10648776; 8468299 YP_001534853.1 TIGRFAM: chlorophyllide reductase subunit Z PFAM: oxidoreductase/nitrogenase component 1; protein of unknown function DUF1197 KEGG: jan:Jann_0177 chlorophyllide reductase subunit Z PMID: 17098896; 10648776; 8468299 YP_001534854.1 PFAM: PufQ cytochrome subunit KEGG: rde:RD1_0108 protein PufQ PMID: 17098896 YP_001534855.1 PFAM: antenna complex alpha/beta subunit KEGG: rsq:Rsph17025_2032 antenna complex, alpha/beta subunit PMID: 17098896; 15879238; Antenna pigment protein beta chain; LH-1 YP_001534856.1 PFAM: antenna complex alpha/beta subunit KEGG: rsh:Rsph17029_1901 antenna complex, alpha/beta subunit PMID: 17098896; 15879238; Antenna pigment protein alpha chain; LH-1 YP_001534857.1 TIGRFAM: photosynthetic reaction center L subunit PFAM: photosynthetic reaction centre protein KEGG: rde:RD1_0104 photosynthetic reaction center L subunit PMID: 17098896; Photosynthetic reaction center L subunit YP_001534858.1 TIGRFAM: photosynthetic reaction center, M subunit PFAM: photosynthetic reaction centre protein KEGG: jan:Jann_0172 photosynthetic reaction center M subunit PMID: 17098896; Photosynthetic reaction center M subunit YP_001534859.1 PFAM: photosynthetic reaction centre cytochrome c subunit KEGG: rde:RD1_0102 photosynthetic reaction center cytochrome c subunit PMID: 17098896 YP_001534860.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001534861.1 KEGG: rsq:Rsph17025_1019 isopentenyl-diphosphate delta-isomerase, type 1 TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1 PFAM: NUDIX hydrolase PMID: 17098896; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase; IPP isomerase YP_001534862.1 TIGRFAM: geranylgeranyl reductase PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase KEGG: jan:Jann_0167 geranylgeranyl reductase PMID: 10572128; 17098896 YP_001534863.1 PFAM: PUCC protein; major facilitator superfamily MFS_1 KEGG: rsp:RSP_0278 putative light-harvesting 1 (B870) complex assembly protein PucC PMID: 17098896 YP_001534864.1 TIGRFAM: bacteriochlorophyll/chlorophyll synthetase PFAM: UbiA prenyltransferase KEGG: jan:Jann_0165 bacteriochlorophyll/chlorophyll synthetase PMID: 17098896 YP_001534865.1 TIGRFAM: PAS sensor protein; transcriptional regulator PpsR PMID: 10735869; 17098896 YP_001534866.1 REFSEQ: ref|ZP_01034604.1 regulatory protein PpaA PMID: 17098896 YP_001534867.1 PFAM: 2-vinyl bacteriochlorophyllide hydratase KEGG: rsh:Rsph17029_1927 2-vinyl bacteriochlorophyllide hydratase PMID: 17098896 YP_001534868.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001534869.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001534870.1 involved in chelation of magnesium into protoporphyrin IX; involved in bacteriochlorophyll biosynthesis; the enzyme from Rhodobacter capsulatus contains an Fe-S cluster; part of a complex with BchI, BchD, and BchH YP_001534871.1 light-independent; with chlN(bchN) and chlB(bchB) reduces ring D of protochlorophyllide to form chlorophyllide a in chlorophyll/bacteriochlorophyll production YP_001534872.1 catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine YP_001534873.1 PFAM: PUCC protein; major facilitator superfamily MFS_1 KEGG: rde:RD1_0134 LhaA protein PMID: 17098896 YP_001534874.1 TIGRFAM: photosynthetic reaction center H subunit PFAM: PRC-barrel domain protein; Photosynthetic reaction centre H subunit KEGG: rde:RD1_0133 photosynthetic reaction center H subunit PMID: 17098896 YP_001534875.1 KEGG: rde:RD1_0132 possible photosynthetic co REFSEQ: ref|ZP_01879036.1 putative photosynthetic complex assembly protein PMID: 17098896 YP_001534876.1 KEGG: rde:RD1_0131 REFSEQ: ref|YP_680552.1 PuhC Protein PMID: 17098896; 17098896 YP_001534877.1 KEGG: rde:RD1_0130 hypothetical protein YP_001534878.1 oxidative; catalyzes the formation of divinylprotochlorophyllide from magnesium-protoporphyrin IX 13-monomethyl ester in isocyclic ring formation in chlorophyll biosynthesis YP_001534879.1 KEGG: rde:RD1_0128 REFSEQ: ref|YP_680549.1 PuhE Protein PMID: 17098896 YP_001534880.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_001534881.1 JTo: PFAM: cytochrome c class I KEGG: jan:Jann_0148 cytochrome c, class I Swiss-Prot: cytochrome c class I, SignalP: signal peptide cleavage between VLA-DD, PSORT: inner membrane PMID: 8611557, 17098896 YP_001534882.1 PFAM: ABC transporter transmembrane region; ABC transporter related SMART: AAA ATPase KEGG: jan:Jann_4278 ABC transporter related YP_001534883.1 PFAM: glycerophosphoryl diester phosphodiesterase KEGG: rde:RD1_1698 glycerophosphoryl diester phosphodiesterase family protein, putative PRK: glpQ; periplasmic YP_001534884.1 Involved in ubiquinone biosynthesis YP_001534885.1 KEGG: sil:SPO0066 proline iminopeptidase TIGRFAM: proline iminopeptidase PFAM: alpha/beta hydrolase fold; PAP; Prolyl aminopeptidase; PIP YP_001534886.1 PFAM: extracellular solute-binding protein family 5 YP_001534887.1 TIGRFAM: acetate--CoA ligase PFAM: AMP-dependent synthetase and ligase KEGG: rde:RD1_2332 acetyl-coenzyme A synthetase; Acyl-activating enzyme; Acetate--CoA ligase YP_001534888.1 PFAM: adenylate kinase; adenylate kinase lid domain protein KEGG: sil:SPO1812 adenylate kinase; ATP-AMP transphosphorylase YP_001534889.1 KEGG: psa:PST_3903 hypothetical protein YP_001534890.1 PFAM: Na+/solute symporter KEGG: sil:SPO1810 sodium/solute symporter family protein YP_001534891.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase putative KEGG: sil:SPO1809 nucleotidyltransferase/CBS/cyclic nucleotide-binding domain protein YP_001534892.1 KEGG: sil:SPO1808 hypothetical protein YP_001534893.1 KEGG: sil:SPO1807 exonuclease, DNA polymerase III, epsilon subunit family TIGRFAM: DNA polymerase III, epsilon subunit PFAM: Exonuclease RNase T and DNA polymerase III SMART: Exonuclease COG0847 YP_001534894.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001534895.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001534896.1 PFAM: protein of unknown function DUF448 YP_001534897.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001534898.1 TIGRFAM: mutator MutT protein PFAM: NUDIX hydrolase KEGG: sil:SPO0060 mutator MutT protein YP_001534899.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001534900.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase KEGG: jan:Jann_0290 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001534901.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001534902.1 no domains found, significant blast hits only to JGI projects, good GC frame plot YP_001534903.1 TIGRFAM: DNA repair protein radc PFAM: DNA repair protein RadC KEGG: pde:Pden_2304 DNA repair protein RadC YP_001534904.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001534905.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001534906.1 KEGG: rde:RD1_0377 alkylated DNA repair protein TIGRFAM: DNA alkylation damage repair protein AlkB, COG: Alkylated DNA repair protein; Alkylated DNA repair protein alkB YP_001534907.1 PFAM: ABC-2 type transporter KEGG: sil:SPO0040 ABC transporter, permease protein YP_001534908.1 TIGRFAM: 3(2),5-bisphosphate nucleotidase PFAM: inositol monophosphatase KEGG: sil:SPO0039 3(2),5-bisphosphate nucleotidase YP_001534909.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001534910.1 PFAM: glycosyl transferase family 2 KEGG: pde:Pden_2298 glycosyl transferase, family 2; family 2 YP_001534911.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase PFAM: Nucleotidyl transferase KEGG: jan:Jann_0218 UTP-glucose-1-phosphate uridylyltransferase,PMID:4284510 YP_001534912.1 PFAM: glycosyl transferase group 1 KEGG: pde:Pden_2295 glycosyl transferase, group 1, COG0438 - Glycosyltransferase; group 1 YP_001534913.1 KEGG: sil:SPO0036 hypothetical protein YP_001534914.1 KEGG: sil:SPO0035 core-2/I-branching enzyme family protein YP_001534915.1 KEGG: jan:Jann_0222 hypothetical protein YP_001534916.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 KEGG: rsq:Rsph17025_2769 PTS IIA-like nitrogen-regulatory protein PtsN, COG1762 - Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) YP_001534917.1 TIGRFAM: ribosomal subunit interface protein PFAM: sigma 54 modulation protein/ribosomal protein S30EA KEGG: rde:RD1_0372 sigma-54 modulation protein, putative YP_001534918.1 TIGRFAM: RNA polymerase sigma-54 factor, RpoN PFAM: sigma-54 factor; sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein KEGG: rsh:Rsph17029_2179 RNA polymerase, sigma 54 subunit, RpoN YP_001534919.1 pfam00005: ABC_tran, COG1137 - ABC-type (unclassified) transport system, ATPase component, BLAST hits to several ABC transporter, ATP-binding protein YP_001534920.1 PFAM: OstA family protein KEGG: rsh:Rsph17029_2816 OstA family protein, COG1934 - Uncharacterized protein conserved in bacteria YP_001534921.1 similar hit in Roseovarius, not conserved throughout many species YP_001534922.1 KEGG: rde:RD1_0368 arabinose 5-phosphate isomerase TIGRFAM: KpsF/GutQ family protein PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001534923.1 PFAM: 3-5 exonuclease YP_001534924.1 pfam07993: NAD_binding_4 domain, COG0702 - Predicted nucleoside-diphosphate-sugar epimerases YP_001534925.1 domain hit: Abi, transmembrane helices predicted, weak BLAST hits YP_001534926.1 no domain hits, no BLAST hit, good GC frame plot over whole length YP_001534927.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001541808.1 PFAM: protein of unknown function DUF305; KEGG: rsh:Rsph17029_3677 protein of unknown function DUF305 YP_001541809.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mes:Meso_4112 ErfK/YbiS/YcfS/YnhG YP_001541810.1 PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sit:TM1040_0289 multicopper oxidase, type 3 YP_001541811.1 KEGG: sit:TM1040_1167 disulphide bond formation protein DsbB YP_001541812.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rde:RD1_0492 ErfK/YbiS/YcfS/YnhG family protein YP_001541813.1 KEGG: sil:SPO0304 lipoprotein, putative YP_001541814.1 SMART: Calcium-binding EF-hand-containing protein; KEGG: rpb:RPB_2375 calcium-binding EF-hand protein YP_001541815.1 PFAM: protein of unknown function DUF302; KEGG: mmr:Mmar10_2335 protein of unknown function DUF302 YP_001541816.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001541817.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: sil:SPOA0365 copper-translocating P-type ATPase YP_001541818.1 PFAM: amino acid permease-associated region; KEGG: sil:SPOA0366 amino acid permease YP_001541820.1 PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: maq:Maqu_3250 cytochrome c biogenesis protein, transmembrane region YP_001541821.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rde:RD1_0492 ErfK/YbiS/YcfS/YnhG family protein YP_001541822.1 KEGG: rde:RD1_0491 hypothetical protein YP_001541823.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: mes:Meso_4212 heavy metal translocating P-type ATPase YP_001541825.1 PFAM: regulatory protein MarR; iron dependent repressor; SMART: regulatory protein Crp; KEGG: mlo:mll2499 hypothetical protein YP_001541826.1 KEGG: sil:SPO2514 hypothetical protein YP_001541827.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: nha:Nham_0025 apolipoprotein N-acyltransferase YP_001541828.1 TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: eli:ELI_04470 putative lipoprotein signal peptidase YP_001541829.1 PFAM: zinc/iron permease; KEGG: gvi:glr4280 zinc transporter, ZIP family YP_001541830.1 PFAM: protein of unknown function DUF411; KEGG: aav:Aave_1809 protein of unknown function DUF411 YP_001541831.1 PFAM: peptidase M23B; KEGG: hch:HCH_06239 membrane protein related to metalloendopeptidase YP_001541832.1 PFAM: electron transport protein SCO1/SenC; KEGG: ccr:CC_3503 SCO1/2 family protein YP_001541833.1 PFAM: protein of unknown function DUF461; KEGG: bra:BRADO4160 conserved hypothetical protein; putative signal peptide YP_001541834.1 PFAM: DSBA oxidoreductase; KEGG: mes:Meso_4133 DsbA oxidoreductase YP_001541835.1 PFAM: Disulphide bond formation protein DsbB; KEGG: psa:PST_0576 disulfide bond formation protein YP_001541836.1 PFAM: electron transport protein SCO1/SenC; KEGG: mag:amb0517 uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems YP_001541837.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sil:SPOA0389 transcriptional regulator, MerR family YP_001541838.1 PFAM: cation efflux protein; KEGG: mes:Meso_4424 cation efflux protein YP_001541839.1 KEGG: ajs:Ajs_1334 hypothetical protein YP_001541840.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: maq:Maqu_3275 cation diffusion facilitator family transporter YP_001541841.1 KEGG: gfo:GFO_1210 hypothetical protein YP_001541842.1 KEGG: sit:TM1040_3830 hypothetical protein YP_001541843.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: acr:Acry_2348 phage integrase family protein YP_001541844.1 PFAM: putative transposase; KEGG: sal:Sala_0067 putative transposase YP_001541845.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: sil:SPO1704 transcriptional regulator, AraC family YP_001541846.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sil:SPO1703 CaiB/BaiF family protein YP_001541847.1 KEGG: sil:SPO1702 hypothetical protein YP_001541848.1 KEGG: sit:TM1040_3826 hypothetical protein YP_001541849.1 PFAM: helix-turn-helix domain protein; KEGG: rsq:Rsph17025_0810 putative transcriptional regulator, XRE family YP_001541850.1 KEGG: sit:TM1040_3824 hypothetical protein YP_001541851.1 KEGG: sit:TM1040_3823 hypothetical protein YP_001541852.1 PFAM: Lytic transglycosylase catalytic; KEGG: sit:TM1040_3822 lytic transglycosylase, catalytic YP_001541853.1 PFAM: Conjugal transfer protein TrbC; KEGG: sit:TM1040_3821 VirB2 type IV secretion YP_001541854.1 PFAM: type IV secretory pathway VirB3 family protein; KEGG: sit:TM1040_3820 type IV secretory pathway, VirB3-like YP_001541855.1 PFAM: CagE TrbE VirB component of type IV transporter system; SMART: AAA ATPase; KEGG: sit:TM1040_3819 CagE, TrbE, VirB component of type IV transporter system YP_001541856.1 KEGG: sit:TM1040_3818 hypothetical protein YP_001541857.1 PFAM: Lytic transglycosylase catalytic; KEGG: sit:TM1040_3817 lytic transglycosylase, catalytic YP_001541858.1 KEGG: sit:TM1040_3816 hypothetical protein YP_001541859.1 PFAM: VirB8 family protein; KEGG: sit:TM1040_3815 VirB8 YP_001541860.1 PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: sit:TM1040_3814 conjugal transfer protein TrbG/VirB9/CagX YP_001541861.1 PFAM: conjugation TrbI family protein; KEGG: sit:TM1040_3813 conjugation TrbI-like protein YP_001541862.1 PFAM: type II secretion system protein E; KEGG: sit:TM1040_3812 type II secretion system protein E YP_001541863.1 KEGG: sit:TM1040_3811 hypothetical protein YP_001541864.1 KEGG: sit:TM1040_3810 hypothetical protein YP_001541865.1 PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: sit:TM1040_3809 TrbL/VirB6 plasmid conjugal transfer protein YP_001541866.1 KEGG: mes:Meso_4413 hypothetical protein YP_001541867.1 PFAM: DNA-directed DNA polymerase; KEGG: psp:PSPPH_4219 DNA polymerase I domain protein YP_001541868.1 KEGG: pna:Pnap_3925 hypothetical protein YP_001541869.1 PFAM: TRAG family protein; KEGG: sit:TM1040_3794 TraG protein YP_001541870.1 PFAM: Relaxase/mobilization nuclease family protein; KEGG: sit:TM1040_3793 relaxase/mobilization nuclease domain YP_001541871.1 PFAM: transposase IS3/IS911 family protein; KEGG: sit:TM1040_3792 hypothetical protein YP_001541872.1 KEGG: sit:TM1040_3791 hypothetical protein YP_001541874.1 KEGG: mes:Meso_4225 hypothetical protein YP_001541875.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: acr:Acry_2348 phage integrase family protein YP_001541876.1 PFAM: putative transposase; KEGG: sal:Sala_0067 putative transposase YP_001541877.1 KEGG: bbt:BBta_1126 putative membrane protein of unknown function YP_001541878.1 KEGG: acr:Acry_3183 hypothetical protein YP_001541879.1 KEGG: gox:GOX2735 PemK-like protein YP_001541880.1 KEGG: rde:RD1_3456 hypothetical protein YP_001541881.1 KEGG: reh:H16_B1492 hypothetical protein YP_001541882.1 PFAM: protein of unknown function UPF0005; KEGG: rsh:Rsph17029_3820 protein of unknown function UPF0005 YP_001541883.1 PFAM: Exopolysaccharide synthesis ExoD; KEGG: jan:Jann_0449 exopolysaccharide synthesis, ExoD YP_001541884.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: sil:SPO0535 K+-dependent Na+/Ca+ exchanger related-protein YP_001541885.1 PFAM: pentapeptide repeat protein; KEGG: tel:tlr0822 hypothetical protein YP_001541886.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: pde:Pden_0723 protein of unknown function DUF21 YP_001541887.1 KEGG: rsp:RSP_0408 hypothetical protein YP_001541888.1 PFAM: cyclic nucleotide-binding; sodium/hydrogen exchanger; KEGG: rde:RD1_3698 sodium/hydrogen exchanger family, putative YP_001541889.1 KEGG: rde:RD1_3698 sodium/hydrogen exchanger family, putative YP_001541890.1 PFAM: transposase Tn3 family protein; KEGG: psb:Psyr_2667 transposase Tn3 YP_001541891.1 KEGG: rsq:Rsph17025_4307 hypothetical protein YP_001541892.1 KEGG: art:Arth_4384 ATP-binding protein YP_001541893.1 PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: art:Arth_4385 integrase, catalytic region YP_001541894.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: gox:GOX2646 DNA integration/recombination/invertion protein YP_001541895.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001541896.1 PFAM: transposase IS4 family protein; KEGG: rde:RD1_3444 transposase, putative YP_001541897.1 PFAM: Resolvase domain; KEGG: psb:Psyr_2668 helix-turn-helix, fis-type YP_001541898.1 KEGG: pfl:PFL_2489 hypothetical protein YP_001541899.1 PFAM: BioY protein; KEGG: bbk:BARBAKC583_1193 biotin transport protein BioY YP_001541900.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sit:TM1040_3661 ABC transporter related YP_001541901.1 PFAM: cobalt transport protein; KEGG: sit:TM1040_3660 cobalt transport protein YP_001541902.1 PFAM: BioY protein; KEGG: mlo:mlr7429 bioY protein YP_001541903.1 KEGG: psb:Psyr_2668 helix-turn-helix, fis-type YP_001541904.1 KEGG: jan:Jann_4220 ParB-like nuclease YP_001541906.1 KEGG: bbt:BBta_7341 hypothetical protein YP_001541907.1 KEGG: sal:Sala_2657 hypothetical protein YP_001541908.1 KEGG: ana:alr7089 hypothetical protein YP_001541909.1 PFAM: DNA primase small subunit; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sfu:Sfum_3271 type III restriction enzyme, res subunit YP_001541910.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sal:Sala_0440 phage integrase YP_001541911.1 PFAM: integrase family protein; KEGG: sal:Sala_0439 phage integrase YP_001541912.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sal:Sala_0438 phage integrase YP_001541913.1 KEGG: nar:Saro_2208 putative methylase/helicase YP_001541914.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: nha:Nham_0858 phage integrase YP_001541915.1 PFAM: putative transposase; KEGG: sal:Sala_0067 putative transposase YP_001541916.1 PFAM: fatty acid hydroxylase; KEGG: pol:Bpro_3325 hypothetical protein YP_001541917.1 PFAM: Integrase catalytic region; KEGG: pde:Pden_3846 integrase, catalytic region YP_001541918.1 PFAM: transposase IS3/IS911 family protein; KEGG: psp:PSPPH_A0090 ISPsy21, transposase orfA YP_001541919.1 KEGG: acr:Acry_0097 transposase, IS4 family protein YP_001541920.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: rpc:RPC_0847 transcriptional regulator, AraC family YP_001541921.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: jan:Jann_1450 TRAP dicarboxylate transporter-DctM subunit YP_001541922.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: jan:Jann_1449 tripartite ATP-independent periplasmic transporter, DctQ component YP_001541923.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sit:TM1040_1591 TRAP dicarboxylate transporter-DctP subunit YP_001541924.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: swi:Swit_3068 short-chain dehydrogenase/reductase SDR YP_001541925.1 PFAM: conserved hypothetical protein; KEGG: ccr:CC_3289 hypothetical protein YP_001541926.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: rpc:RPC_0842 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001541927.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bxe:Bxe_A2070 transcriptional regulator, LysR family YP_001541928.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: bja:blr3531 hypothetical protein YP_001541929.1 PFAM: aldehyde dehydrogenase; KEGG: rpc:RPC_0853 aldehyde dehydrogenase YP_001541930.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: rpc:RPC_0847 transcriptional regulator, AraC family YP_001541931.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; cyclase/dehydrase; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; carbon monoxide dehydrogenase subunit G; KEGG: rpc:RPC_0848 carbon-monoxide dehydrogenase YP_001541932.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: acr:Acry_0669 molybdopterin dehydrogenase, FAD-binding YP_001541933.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: rpc:RPC_0850 (2Fe-2S)-binding YP_001541934.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rpc:RPC_0851 AMP-dependent synthetase and ligase YP_001541935.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: acr:Acry_0672 enoyl-CoA hydratase/isomerase YP_001541936.1 PFAM: Extracellular ligand-binding receptor; KEGG: rpc:RPC_0836 extracellular ligand-binding receptor YP_001541937.1 PFAM: inner-membrane translocator; KEGG: rpc:RPC_0837 inner-membrane translocator YP_001541938.1 PFAM: inner-membrane translocator; KEGG: rpc:RPC_0838 inner-membrane translocator YP_001541939.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rpc:RPC_0839 ABC transporter related YP_001541940.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rpc:RPC_0840 ABC transporter related YP_001541941.1 KEGG: psa:PST_3459 hypothetical protein YP_001541942.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation YP_001541943.1 KEGG: rde:RD1_A0106 RC187 YP_001541945.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: rde:RD1_A0072 plasmid stabilization protein, putative YP_001541946.1 KEGG: swi:Swit_5197 transposase IS116/IS110/IS902 family protein YP_001541947.1 PFAM: Integrase catalytic region; KEGG: pde:Pden_3846 integrase, catalytic region YP_001541948.1 PFAM: transposase IS3/IS911 family protein; KEGG: psp:PSPPH_A0090 ISPsy21, transposase orfA YP_001541949.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: cph:Cpha266_0024 transposase YP_001541950.1 PFAM: Integrase catalytic region; KEGG: bms:BRA1116 IS3 family element, transposase orfB YP_001541952.1 PFAM: domain of unknown function DUF1738; KEGG: nha:Nham_4029 peptidase M, neutral zinc metallopeptidases, zinc-binding site YP_001541954.1 PFAM: replication protein C; KEGG: rde:RD1_A0024 replication protein C YP_001541955.1 KEGG: rde:RD1_A0023 RC101 YP_001541956.1 KEGG: rde:RD1_A0021 RC102 YP_001541958.1 KEGG: mlo:mlr9349 hypothetical protein YP_001541959.1 PFAM: Resolvase domain; KEGG: rsp:RSP_2482 TonB-dependent receptor protein YP_001541960.1 TIGRFAM: putative addiction module antidote protein, CC2985 family; PFAM: CopG domain protein DNA-binding domain protein; KEGG: nwi:Nwi_3093 helix-turn-helix protein, CopG YP_001541961.1 PFAM: plasmid stabilization system; KEGG: nwi:Nwi_3092 plasmid stabilization system YP_001541962.1 PFAM: integrase family protein; KEGG: rsq:Rsph17025_4239 hypothetical protein YP_001541963.1 PFAM: protein of unknown function DUF1403; KEGG: sit:TM1040_3403 protein of unknown function DUF1403 YP_001541964.1 PFAM: chromosome segregation and condensation protein ScpB; KEGG: rsq:Rsph17025_4232 hypothetical protein YP_001541965.1 PFAM: WGR domain protein; KEGG: mlo:msl9076 hypothetical protein YP_001541966.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: atc:AGR_pAT_503 hypothetical protein YP_001541968.1 KEGG: pde:Pden_2059 transposase orfA IS5 family element YP_001541969.1 PFAM: transposase IS4 family protein; KEGG: pde:Pden_3333 transposase, IS4 family protein YP_001541970.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: rru:Rru_A0676 transposase IS116/IS110/IS902 YP_001541971.1 KEGG: rsq:Rsph17025_2803 ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_001541972.1 KEGG: nha:Nham_4014 ISSpo6, transposase orf A YP_001541973.1 KEGG: nha:Nham_4013 ISSpo6, transposase OrfB YP_001541974.1 KEGG: sru:SRU_1982 hypothetical protein YP_001541975.1 PFAM: cyclic nucleotide-binding; KEGG: reh:H16_A1838 transcriptional regulator, NNR like YP_001541976.1 PFAM: protein of unknown function DUF411; KEGG: rde:RD1_2307 hypothetical protein YP_001541977.1 PFAM: fatty acid hydroxylase; KEGG: aeh:Mlg_0287 sterol desaturase-like protein YP_001541978.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: dge:Dgeo_0215 cation diffusion facilitator family transporter YP_001541979.1 PFAM: SNARE associated Golgi protein; KEGG: sil:SPOA0363 hypothetical protein YP_001541980.1 KEGG: ddi:DDBDRAFT_0184550 hypothetical protein YP_001541981.1 KEGG: maq:Maqu_0306 ion transport 2 domain protein YP_001541982.1 KEGG: rde:RD1_1666 hypothetical protein YP_001541983.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sil:SPOA0357 DNA-binding response regulator YP_001541984.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sil:SPOA0358 sensor histidine kinase YP_001541985.1 KEGG: aeh:Mlg_1384 hypothetical protein YP_001541986.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: mag:amb4200 cytochrome c biogenesis factor YP_001541987.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mlo:mll4330 cytochrome c biogenesis protein CycX YP_001541988.1 PFAM: cytochrome C biogenesis protein; KEGG: atc:AGR_C_1789 cytochrome C-type biogenesis protein YP_001541989.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: smd:Smed_0633 cytochrome c-type biogenesis transmembrane protein YP_001541990.1 KEGG: mag:amb3382 thiol:disulfide interchange protein DsbD 1 precursor YP_001541992.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sil:SPO2205 ErfK/YbiS/YcfS/YnhG family protein YP_001541993.1 PFAM: cytochrome c class I; KEGG: sil:SPOA0359 cytochrome c family protein YP_001541994.1 KEGG: ret:RHE_CH02511 putative cytochrome c-like protein YP_001541995.1 KEGG: psa:PST_0453 cytochrome c family protein YP_001541996.1 PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sil:SPOA0360 multicopper oxidase, putative YP_001541997.1 PFAM: cytochrome c class I; KEGG: sil:SPOA0361 cytochrome c family protein YP_001541998.1 PFAM: DSBA oxidoreductase; KEGG: sil:SPOA0362 27kDa outer membrane protein YP_001541999.1 PFAM: Heavy metal transport/detoxification protein; KEGG: pen:PSEEN0671 copper-binding protein YP_001542000.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sil:SPO0794 copper-translocating P-type ATPase YP_001542001.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sit:TM1040_0537 transcriptional regulator, MerR family YP_001542002.1 PFAM: glutaredoxin; KEGG: eli:ELI_04570 hypothetical protein YP_001542003.1 PFAM: extracellular solute-binding protein family 5; KEGG: rme:Rmet_1932 extracellular solute-binding protein, family 5 YP_001542004.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pol:Bpro_0381 binding-protein-dependent transport systems inner membrane component YP_001542005.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pol:Bpro_0382 binding-protein-dependent transport systems inner membrane component YP_001542006.1 KEGG: pol:Bpro_0383 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001542007.1 KEGG: rpa:RPA0755 putative oligopeptide ABC transporter, ATP-binding component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001542008.1 PFAM: Asp/Glu racemase; KEGG: rsq:Rsph17025_3633 hypothetical protein YP_001542009.1 PFAM: NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30; KEGG: rde:RD1_3877 hypothetical protein YP_001542010.1 PFAM: HupE/UreJ protein; KEGG: bra:BRADO6336 conserved hypothetical protein; putative [NiFe]-hydrogenase/urease accessory HupE/UreJ family protein YP_001542011.1 KEGG: bbt:BBta_1289 putative membrane protein of unknown function YP_001542012.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: rde:RD1_2195 catalase-peroxidase YP_001542013.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rde:RD1_2194 oxidative stress transcription regulator, OxyR, putative YP_001542015.1 PFAM: regulatory protein LuxR; KEGG: rle:RL1113 putative transcriptional regulator YP_001542016.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001542017.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001542018.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001542019.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001542020.1 PFAM: multiple resistance and pH regulation protein F; KEGG: jan:Jann_3719 multiple resistance and pH regulation protein F YP_001542021.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: jan:Jann_3720 Na+/H+ antiporter subunit YP_001542022.1 KEGG: sit:TM1040_2622 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969 YP_001542023.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_001542024.1 PFAM: regulatory protein MarR; KEGG: pde:Pden_3546 transcriptional regulator, MarR family YP_001542025.1 PFAM: beta-lactamase domain protein; KEGG: sil:SPO0683 metallo-beta-lactamase family protein YP_001542026.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: sil:SPO0682 monooxygenase family protein YP_001542027.1 KEGG: sil:SPO0681 hypothetical protein YP_001542028.1 KEGG: sil:SPO0758 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase YP_001542029.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001542030.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001542031.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: sit:TM1040_3726 phenylacetate-CoA oxygenase, PaaI subunit YP_001542032.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: jan:Jann_0652 phenylacetate-CoA oxygenase, PaaJ subunit YP_001542033.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sil:SPO0753 phenylacetic acid degradation oxidoreductase PaaK YP_001542034.1 PFAM: regulatory protein TetR; KEGG: sil:SPO0743 transcriptional regulator, TetR family YP_001542035.1 TIGRFAM: phenylacetate-CoA ligase; KEGG: sil:SPO0742 phenylacetate-CoA ligase YP_001542036.1 TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: sil:SPO0741 phenylacetic acid degradation protein PaaD YP_001542037.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: sil:SPO0739 enoyl-CoA hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase YP_001542038.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_001542039.1 PFAM: PaaX domain protein; KEGG: sil:SPO0734 PaaX domain protein YP_001542041.1 PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: mlo:mlr4225 glycerol-3-phosphate dehydrogenase YP_001542042.1 PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: tbd:Tbd_2627 alpha,alpha-trehalose-phosphate synthase YP_001542043.1 KEGG: tbd:Tbd_2626 glucosyl-glycerol-phosphate synthase; TIGRFAM: glucosylglycerol-phosphate synthase; PFAM: glycosyl transferase family 20 YP_001542044.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: rde:RD1_2477 phospholipase D, putative YP_001542045.1 PFAM: histidine kinase HAMP region domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: jan:Jann_3564 signal transduction histidine kinase YP_001542046.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001542048.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media YP_001542049.1 KEGG: rde:RD1_4211 hypothetical protein YP_001542050.1 PFAM: Ferritin Dps family protein; KEGG: sit:TM1040_2721 ferritin and Dps YP_001542051.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rde:RD1_2449 acetolactate synthase YP_001542052.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001542053.1 PFAM: protein of unknown function DUF1328; KEGG: rso:RS02225 probable transmembrane protein YP_001542055.1 PFAM: cyclic nucleotide-binding; KEGG: rde:RD1_2451 nitrogen fixation regulatory protein FixK , putative YP_001542056.1 SMART: ParB domain protein nuclease; KEGG: pde:Pden_2912 replication protein, putative YP_001542057.1 KEGG: rsh:Rsph17029_2919 hypothetical protein YP_001542058.1 KEGG: jan:Jann_2179 hypothetical protein YP_001542059.1 KEGG: gfo:GFO_0298 hypothetical protein YP_001542061.1 KEGG: rsq:Rsph17025_2741 hypothetical protein YP_001542062.1 PFAM: Resolvase domain; KEGG: rsp:RSP_2482 TonB-dependent receptor protein YP_001542063.1 KEGG: sit:TM1040_3772 RepA YP_001542064.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sit:TM1040_3773 cobyrinic acid a,c-diamide synthase YP_001542065.1 SMART: ParB domain protein nuclease; KEGG: rsp:RSP_7084 ParB-like nuclease YP_001542066.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: rsh:Rsph17029_2850 polysaccharide biosynthesis protein CapD YP_001542067.1 PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: rsp:RSP_1187 hypothetical protein YP_001542068.1 KEGG: rsh:Rsph17029_2848 hypothetical protein YP_001542070.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: xcv:XCV3705 UDP-glucose dehydrogenase YP_001542072.1 KEGG: ter:Tery_3237 hypothetical protein YP_001542073.1 PFAM: sulfotransferase; KEGG: rsh:Rsph17029_4075 sulfotransferase YP_001542074.1 KEGG: ter:Tery_4433 hypothetical protein YP_001542075.1 PFAM: glycosyl transferase group 1; KEGG: jan:Jann_4244 glycosyl transferase, group 1 YP_001542076.1 KEGG: nar:Saro_0725 chromosome segregation ATPases-like YP_001542077.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: mpt:Mpe_A1914 UDP-glucose 4-epimerase YP_001542078.1 KEGG: ter:Tery_3237 hypothetical protein YP_001542079.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: rru:Rru_A0562 peptidase S1 and S6, chymotrypsin/Hap YP_001542080.1 KEGG: pde:Pden_2124 hemolysin-type calcium-binding region YP_001542081.1 PFAM: Hemolysin-type calcium-binding region; KEGG: rde:RD1_A0054 iron-regulated protein FrpC, putative YP_001542082.1 KEGG: sil:SPOA0441 hypothetical protein YP_001542083.1 KEGG: art:Arth_4384 ATP-binding protein YP_001542084.1 PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: art:Arth_4385 integrase, catalytic region YP_001542085.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: gox:GOX2646 DNA integration/recombination/invertion protein YP_001542086.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001542087.1 PFAM: transposase IS4 family protein; KEGG: rde:RD1_3444 transposase, putative YP_001542091.1 KEGG: rde:RD1_A0058 transposase, putative YP_001542092.1 KEGG: pat:Patl_4083 hypothetical protein YP_001542093.1 PFAM: multi antimicrobial extrusion protein MatE; polysaccharide biosynthesis protein; KEGG: rde:RD1_2470 MatE efflux family protein YP_001542094.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: rde:RD1_2477 phospholipase D, putative YP_001542095.1 KEGG: rpd:RPD_2508 hypothetical protein YP_001542096.1 PFAM: cytochrome c class I; KEGG: psa:PST_1611 cytochrome c6 YP_001542097.1 PFAM: amine oxidase; KEGG: psa:PST_1610 flavin monoamine oxidase-related protein YP_001542098.1 KEGG: nwi:Nwi_2311 hypothetical protein YP_001542100.1 TIGRFAM: Cytochrome c oxidase subunit I type; PFAM: cytochrome c oxidase subunit I; KEGG: eba:ebA156 putative cytochrome c oxidase subunit I YP_001542101.1 TIGRFAM: Cytochrome c oxidase subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: mes:Meso_2792 cytochrome c oxidase, subunit II YP_001542102.1 PFAM: cytochrome c class I; KEGG: eba:ebA4540 cytochrome c1, probably related to cytocrome c oxidase function YP_001542103.1 KEGG: psa:PST_2844 cytochrome c type protein YP_001542104.1 PFAM: FAD dependent oxidoreductase; KEGG: nha:Nham_4244 putative gluconate dehydrogenase YP_001542105.1 KEGG: bvi:Bcep1808_4793 hypothetical protein YP_001542106.1 PFAM: MgtC/SapB transporter; KEGG: mes:Meso_3446 MgtC/SapB transporter YP_001542107.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: xcb:XC_1642 alpha-glucosidase YP_001542108.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rru:Rru_A3667 short-chain dehydrogenase/reductase SDR YP_001542109.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: psa:PST_3887 probable short-chain dehydrogenase YP_001542110.1 PFAM: acriflavin resistance protein; KEGG: sru:SRU_0473 multidrug efflux transporter, AcrB/AcrD/AcrF family YP_001542111.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: vpa:VPA0343 putative membrane fusion protein YP_001542112.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cmi:CMM_2063 short chain dehydrogenase/oxidoreductase YP_001542113.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: sru:SRU_0355 sodium/glucose cotransporter 2 YP_001542114.1 PFAM: MscS Mechanosensitive ion channel; KEGG: bra:BRADO5370 conserved hypothetical protein; putative membrane protein; putative small-conductance mechanosensitive channel YP_001542115.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: sru:SRU_0355 sodium/glucose cotransporter 2 YP_001542116.1 PFAM: sodium/calcium exchanger membrane region; KEGG: eli:ELI_06950 cation antiporter (Na+/Ca2+) YP_001542117.1 PFAM: protein of unknown function UPF0118; KEGG: cps:CPS_2311 hypothetical protein YP_001542118.1 KEGG: tcx:Tcr_1058 hypothetical protein YP_001542120.1 KEGG: rpe:RPE_2181 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001542121.1 PFAM: Ferritin Dps family protein; KEGG: pcr:Pcryo_0735 ferritin and Dps YP_001542122.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rde:RD1_2464 trk potassium uptake system protein YP_001542123.1 PFAM: cation transporter; KEGG: rde:RD1_2465 trk potassium uptake system protein, transmembrane component YP_001542124.1 PFAM: protein of unknown function UPF0057; KEGG: rxy:Rxyl_0694 protein of unknown function UPF0057 YP_001542125.1 KEGG: rde:RD1_2473 hypothetical protein YP_001542126.1 KEGG: mlo:mlr3233 hypothetical protein YP_001542127.1 KEGG: sde:Sde_3869 hypothetical protein YP_001542128.1 PFAM: transposase IS3/IS911 family protein; KEGG: xac:XAC4322 ISxac3 transposase YP_001542129.1 KEGG: ajs:Ajs_1844 integrase, catalytic region YP_001542130.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_0556 ISEhe3 orfB YP_001542131.1 KEGG: rde:RD1_2466 transport protein, putative YP_001542132.1 KEGG: rde:RD1_2471 hypothetical protein YP_001542134.1 PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: csa:Csal_1160 peptidase C26 YP_001542135.1 KEGG: ilo:IL1070 hypothetical protein YP_001542136.1 KEGG: pnu:Pnuc_1656 hypothetical protein YP_001542137.1 PFAM: homocysteine S-methyltransferase; KEGG: sil:SPO3398 homocysteine S-methyltransferase family protein YP_001542138.1 KEGG: pna:Pnap_3267 hypothetical protein YP_001542139.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rsp:RSP_3339 transcriptional regulator, GntR family YP_001542140.1 PFAM: glutaredoxin; KEGG: eli:ELI_04570 hypothetical protein YP_001542141.1 PFAM: protein of unknown function DUF305; KEGG: rsh:Rsph17029_3677 protein of unknown function DUF305 YP_001542142.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mes:Meso_4112 ErfK/YbiS/YcfS/YnhG YP_001542143.1 PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sit:TM1040_0289 multicopper oxidase, type 3 YP_001542144.1 KEGG: sit:TM1040_1167 disulphide bond formation protein DsbB YP_001542145.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rde:RD1_0492 ErfK/YbiS/YcfS/YnhG family protein YP_001542146.1 KEGG: sil:SPO0304 lipoprotein, putative YP_001542147.1 SMART: Calcium-binding EF-hand-containing protein; KEGG: rpb:RPB_2375 calcium-binding EF-hand protein YP_001542148.1 PFAM: protein of unknown function DUF302; KEGG: mmr:Mmar10_2335 protein of unknown function DUF302 YP_001542149.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001542150.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: sil:SPOA0365 copper-translocating P-type ATPase YP_001542151.1 PFAM: amino acid permease-associated region; KEGG: sil:SPOA0366 amino acid permease YP_001542153.1 PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: maq:Maqu_3250 cytochrome c biogenesis protein, transmembrane region YP_001542154.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rde:RD1_0492 ErfK/YbiS/YcfS/YnhG family protein YP_001542155.1 KEGG: rde:RD1_0491 hypothetical protein YP_001542156.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: mes:Meso_4212 heavy metal translocating P-type ATPase YP_001542158.1 PFAM: regulatory protein MarR; iron dependent repressor; SMART: regulatory protein Crp; KEGG: mlo:mll2499 hypothetical protein YP_001542159.1 KEGG: sil:SPO2514 hypothetical protein YP_001542160.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: nha:Nham_0025 apolipoprotein N-acyltransferase YP_001542161.1 TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: eli:ELI_04470 putative lipoprotein signal peptidase YP_001542162.1 PFAM: zinc/iron permease; KEGG: gvi:glr4280 zinc transporter, ZIP family YP_001542163.1 PFAM: protein of unknown function DUF411; KEGG: aav:Aave_1809 protein of unknown function DUF411 YP_001542164.1 PFAM: peptidase M23B; KEGG: hch:HCH_06239 membrane protein related to metalloendopeptidase YP_001542165.1 PFAM: electron transport protein SCO1/SenC; KEGG: ccr:CC_3503 SCO1/2 family protein YP_001542166.1 PFAM: protein of unknown function DUF461; KEGG: bra:BRADO4160 conserved hypothetical protein; putative signal peptide YP_001542167.1 PFAM: DSBA oxidoreductase; KEGG: mes:Meso_4133 DsbA oxidoreductase YP_001542168.1 PFAM: Disulphide bond formation protein DsbB; KEGG: psa:PST_0576 disulfide bond formation protein YP_001542169.1 PFAM: electron transport protein SCO1/SenC; KEGG: mag:amb0517 uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems YP_001542170.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sil:SPOA0389 transcriptional regulator, MerR family YP_001542171.1 PFAM: cation efflux protein; KEGG: mes:Meso_4424 cation efflux protein YP_001542172.1 KEGG: ajs:Ajs_1334 hypothetical protein YP_001542173.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: maq:Maqu_3275 cation diffusion facilitator family transporter YP_001542174.1 KEGG: gfo:GFO_1210 hypothetical protein YP_001542175.1 KEGG: sit:TM1040_3830 hypothetical protein YP_001542176.1 PFAM: regulatory protein ArsR; KEGG: mkm:Mkms_5742 regulatory protein, ArsR YP_001542177.1 PFAM: cation efflux protein; KEGG: sal:Sala_2560 hypothetical protein YP_001542178.1 KEGG: sit:TM1040_3826 hypothetical protein YP_001542179.1 PFAM: helix-turn-helix domain protein; KEGG: rsq:Rsph17025_0810 putative transcriptional regulator, XRE family YP_001542180.1 KEGG: sit:TM1040_3824 hypothetical protein YP_001542181.1 KEGG: sit:TM1040_3823 hypothetical protein YP_001542182.1 PFAM: Lytic transglycosylase catalytic; KEGG: sit:TM1040_3822 lytic transglycosylase, catalytic YP_001542183.1 PFAM: Conjugal transfer protein TrbC; KEGG: sit:TM1040_3821 VirB2 type IV secretion YP_001542184.1 PFAM: type IV secretory pathway VirB3 family protein; KEGG: sit:TM1040_3820 type IV secretory pathway, VirB3-like YP_001542185.1 PFAM: CagE TrbE VirB component of type IV transporter system; SMART: AAA ATPase; KEGG: sit:TM1040_3819 CagE, TrbE, VirB component of type IV transporter system YP_001542186.1 KEGG: sit:TM1040_3818 hypothetical protein YP_001542187.1 PFAM: Lytic transglycosylase catalytic; KEGG: sit:TM1040_3817 lytic transglycosylase, catalytic YP_001542188.1 KEGG: sit:TM1040_3816 hypothetical protein YP_001542189.1 PFAM: VirB8 family protein; KEGG: sit:TM1040_3815 VirB8 YP_001542190.1 PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: sit:TM1040_3814 conjugal transfer protein TrbG/VirB9/CagX YP_001542191.1 PFAM: conjugation TrbI family protein; KEGG: sit:TM1040_3813 conjugation TrbI-like protein YP_001542192.1 PFAM: type II secretion system protein E; KEGG: sit:TM1040_3812 type II secretion system protein E YP_001542193.1 KEGG: sit:TM1040_3810 hypothetical protein YP_001542194.1 PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: sit:TM1040_3809 TrbL/VirB6 plasmid conjugal transfer protein YP_001542195.1 KEGG: rru:Rru_A0809 hypothetical protein YP_001542196.1 KEGG: ter:Tery_4988 hypothetical protein YP_001542197.1 PFAM: TRAG family protein; KEGG: sit:TM1040_3794 TraG protein YP_001542198.1 PFAM: Relaxase/mobilization nuclease family protein; KEGG: sit:TM1040_3793 relaxase/mobilization nuclease domain YP_001542199.1 KEGG: sit:TM1040_3792 hypothetical protein YP_001542200.1 KEGG: sit:TM1040_3791 hypothetical protein YP_001542201.1 KEGG: sit:TM1040_3771 hypothetical protein YP_001542202.1 KEGG: mes:Meso_4225 hypothetical protein YP_001542203.1 PFAM: protein of unknown function DUF159; KEGG: bbt:BBta_3432 hypothetical protein YP_001542204.1 KEGG: sil:SPO0672 hypothetical protein YP_001542205.1 KEGG: sil:SPO0671 hypothetical protein YP_001542206.1 KEGG: sit:TM1040_0175 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein YP_001542207.1 KEGG: jan:Jann_4220 ParB-like nuclease YP_001542209.1 KEGG: bbt:BBta_7341 hypothetical protein YP_001542210.1 KEGG: sal:Sala_2657 hypothetical protein YP_001542211.1 KEGG: ana:alr7089 hypothetical protein YP_001542212.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sal:Sala_0438 phage integrase YP_001542213.1 PFAM: integrase family protein; KEGG: sal:Sala_0439 phage integrase YP_001542214.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sal:Sala_0440 phage integrase YP_001542215.1 PFAM: DNA primase small subunit; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sfu:Sfum_3271 type III restriction enzyme, res subunit YP_001542216.1 KEGG: nar:Saro_2208 putative methylase/helicase YP_001542217.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pol:Bpro_1615 transcriptional regulator, LysR family YP_001542218.1 KEGG: lpn:lpg1968 hypothetical protein YP_001542219.1 KEGG: psa:PST_3459 hypothetical protein YP_001542220.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation YP_001542221.1 KEGG: rde:RD1_A0106 RC187 YP_001542223.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: rde:RD1_A0072 plasmid stabilization protein, putative YP_001542224.1 KEGG: jan:Jann_4219 hypothetical protein YP_001542226.1 PFAM: domain of unknown function DUF1738; KEGG: nha:Nham_4029 peptidase M, neutral zinc metallopeptidases, zinc-binding site YP_001542228.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: rsq:Rsph17025_4217 hypothetical protein YP_001542229.1 PFAM: replication protein C; KEGG: rsp:RSP_7387 replication initiator RepC YP_001542230.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: rsp:RSP_4185 RepB partitioning protein/ParB-like protein YP_001542231.1 PFAM: regulatory protein MerR; Cobyrinic acid ac-diamide synthase; KEGG: rsp:RSP_4186 RepA partitioning protein/ATPase, ParA type YP_001542232.1 PFAM: SpoVT/AbrB domain protein; KEGG: rsp:RSP_7280 SpoVT/AbrB-like cell growth regulatory protein YP_001542233.1 KEGG: rsp:RSP_4188 hypothetical memebrane protein YP_001542234.1 PFAM: Resolvase domain; KEGG: rsp:RSP_2482 TonB-dependent receptor protein YP_001542235.1 PFAM: integrase family protein; KEGG: rsq:Rsph17025_4239 hypothetical protein YP_001542236.1 PFAM: protein of unknown function DUF1403; KEGG: sit:TM1040_3403 protein of unknown function DUF1403 YP_001542237.1 PFAM: chromosome segregation and condensation protein ScpB; KEGG: rsq:Rsph17025_4232 hypothetical protein YP_001542238.1 PFAM: WGR domain protein; KEGG: mlo:msl9076 hypothetical protein YP_001542239.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: atc:AGR_pAT_503 hypothetical protein YP_001542241.1 KEGG: pde:Pden_2059 transposase orfA IS5 family element YP_001542242.1 PFAM: transposase IS4 family protein; KEGG: pde:Pden_3333 transposase, IS4 family protein YP_001542243.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: rru:Rru_A0676 transposase IS116/IS110/IS902 YP_001542244.1 KEGG: rsq:Rsph17025_2803 ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_001542245.1 KEGG: nha:Nham_4014 ISSpo6, transposase orf A YP_001542246.1 KEGG: nha:Nham_4013 ISSpo6, transposase OrfB YP_001542247.1 KEGG: sru:SRU_1982 hypothetical protein YP_001542248.1 PFAM: cyclic nucleotide-binding; KEGG: reh:H16_A1838 transcriptional regulator, NNR like YP_001542249.1 PFAM: protein of unknown function DUF411; KEGG: rde:RD1_2307 hypothetical protein YP_001542250.1 PFAM: fatty acid hydroxylase; KEGG: aeh:Mlg_0287 sterol desaturase-like protein YP_001542251.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: dge:Dgeo_0215 cation diffusion facilitator family transporter YP_001542252.1 PFAM: SNARE associated Golgi protein; KEGG: sil:SPOA0363 hypothetical protein YP_001542253.1 KEGG: ddi:DDBDRAFT_0184550 hypothetical protein YP_001542254.1 KEGG: maq:Maqu_0306 ion transport 2 domain protein YP_001542255.1 KEGG: rde:RD1_1666 hypothetical protein YP_001542256.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sil:SPOA0357 DNA-binding response regulator YP_001542257.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sil:SPOA0358 sensor histidine kinase YP_001542258.1 KEGG: aeh:Mlg_1384 hypothetical protein YP_001542259.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: mag:amb4200 cytochrome c biogenesis factor YP_001542260.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mlo:mll4330 cytochrome c biogenesis protein CycX YP_001542261.1 PFAM: cytochrome C biogenesis protein; KEGG: atc:AGR_C_1789 cytochrome C-type biogenesis protein YP_001542262.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: smd:Smed_0633 cytochrome c-type biogenesis transmembrane protein YP_001542263.1 KEGG: mag:amb3382 thiol:disulfide interchange protein DsbD 1 precursor YP_001542265.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sil:SPO2205 ErfK/YbiS/YcfS/YnhG family protein YP_001542266.1 PFAM: cytochrome c class I; KEGG: sil:SPOA0359 cytochrome c family protein YP_001542267.1 KEGG: ret:RHE_CH02511 putative cytochrome c-like protein YP_001542268.1 KEGG: psa:PST_0453 cytochrome c family protein YP_001542269.1 PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sil:SPOA0360 multicopper oxidase, putative YP_001542270.1 PFAM: cytochrome c class I; KEGG: sil:SPOA0361 cytochrome c family protein YP_001542271.1 PFAM: DSBA oxidoreductase; KEGG: sil:SPOA0362 27kDa outer membrane protein YP_001542272.1 PFAM: Heavy metal transport/detoxification protein; KEGG: pen:PSEEN0671 copper-binding protein YP_001542273.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sil:SPO0794 copper-translocating P-type ATPase YP_001542274.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sit:TM1040_0537 transcriptional regulator, MerR family YP_001542276.1 SMART: Parallel beta-helix repeat; KEGG: tcx:Tcr_0105 VCBS YP_001542277.1 PFAM: transposase IS3/IS911 family protein; KEGG: xac:XAC4322 ISxac3 transposase YP_001542279.1 KEGG: rsp:RSP_3838 capsule polysaccharide export protein YP_001542280.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pde:Pden_5037 ABC transporter related YP_001542282.1 PFAM: transposase IS4 family protein; KEGG: rde:RD1_3444 transposase, putative YP_001542283.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001542284.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: gox:GOX2646 DNA integration/recombination/invertion protein YP_001542285.1 PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: art:Arth_4385 integrase, catalytic region YP_001542286.1 KEGG: art:Arth_4384 ATP-binding protein YP_001542287.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: swi:Swit_5093 resolvase, N-terminal domain YP_001542288.1 PFAM: WGR domain protein; KEGG: rsq:Rsph17025_4211 hypothetical protein YP_001542289.1 KEGG: noc:Noc_2541 hypothetical protein YP_001542290.1 PFAM: plasmid stabilization system; KEGG: pha:PSHAa2625 hypothetical protein YP_001542292.1 PFAM: Integrase catalytic region; KEGG: bbt:BBta_7691 integrase, catalytic domain YP_001542293.1 PFAM: transposase IS3/IS911 family protein; KEGG: mag:amb0646 insertion element ISR1 hypothetical 10 kDa protein A3 YP_001542295.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: rru:Rru_A0676 transposase IS116/IS110/IS902 YP_001542296.1 PFAM: transposase IS4 family protein; KEGG: pde:Pden_3333 transposase, IS4 family protein YP_001542297.1 KEGG: pde:Pden_2059 transposase orfA IS5 family element YP_001542298.1 KEGG: bra:BRADO4296 putative insertion element (IS) transposase YP_001542300.1 PFAM: replication protein C; KEGG: rsp:RSP_7387 replication initiator RepC YP_001542301.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: rsp:RSP_4185 RepB partitioning protein/ParB-like protein YP_001542302.1 PFAM: regulatory protein MerR; Cobyrinic acid ac-diamide synthase; KEGG: rsp:RSP_4186 RepA partitioning protein/ATPase, ParA type YP_001542303.1 PFAM: Resolvase domain; KEGG: rsp:RSP_2482 TonB-dependent receptor protein YP_001542304.1 KEGG: rsh:Rsph17029_2968 hypothetical protein YP_001542305.1 KEGG: smd:Smed_5442 transcriptional regulator YP_001542309.1 PFAM: integrase family protein; KEGG: shn:Shewana3_2354 phage integrase family protein YP_001542310.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: rpe:RPE_3949 prevent-host-death family protein YP_001542311.1 TIGRFAM: death-on-curing family protein; PFAM: Death-on-curing protein; KEGG: hne:HNE_0348 putative addiction module toxin YP_001542312.1 KEGG: sit:TM1040_3863 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_001542313.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: rde:RD1_B0019 dTDP-glucose 4,6-dehydratase YP_001542315.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: rsp:RSP_3845 dTDP-4-dehydrorhamnose reductase YP_001542316.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sit:TM1040_3859 glucose-1-phosphate thymidylyltransferase YP_001542317.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: rsq:Rsph17025_2629 NAD-dependent epimerase/dehydratase YP_001542318.1 PFAM: sugar transferase; KEGG: rsh:Rsph17029_2851 sugar transferase YP_001542319.1 PFAM: glycosyl transferase family 2; KEGG: aav:Aave_4142 glycosyl transferase, family 2 YP_001542322.1 KEGG: acr:Acry_3373 IstB domain protein ATP-binding protein YP_001542323.1 PFAM: polysaccharide biosynthesis protein; KEGG: bvi:Bcep1808_6521 polysaccharide biosynthesis protein YP_001542324.1 SMART: Parallel beta-helix repeat YP_001542325.1 PFAM: Oligosaccharide biosynthesis protein Alg14 like; KEGG: mjl:Mjls_0958 oligosaccharide biosynthesis protein Alg14 like YP_001542326.1 PFAM: Glycosyltransferase 28 domain; KEGG: rle:RL3655 putative glycosyltransferase YP_001542327.1 KEGG: psa:PST_2497 hypothetical protein YP_001542328.1 PFAM: polysaccharide pyruvyl transferase; KEGG: mfa:Mfla_2020 polysaccharide pyruvyl transferase YP_001542329.1 KEGG: smd:Smed_4799 hypothetical protein YP_001542331.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: rle:pRL90133 putative GDP-mannose 4,6-dehydratase YP_001542332.1 PFAM: sulfotransferase; KEGG: bta:282485 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 YP_001542333.1 KEGG: ava:Ava_1042 methyltransferase FkbM YP_001542334.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: ath:AT1G73250 ATFX/GER1 (GDP-4-KETO-6-DEOXYMANNOSE-3,5-EPIMERASE-4-REDUCTASE 1); GDP-L-fucose synthase YP_001542335.1 PFAM: glycosyl transferase family 2; KEGG: nha:Nham_3045 glycosyl transferase, family 2 YP_001542336.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: dde:Dde_3680 acetyltransferase (isoleucine patch superfamily)-like YP_001542337.1 PFAM: glycosyl transferase family 2; KEGG: nar:Saro_3226 glycosyl transferase, family 2 YP_001542338.1 KEGG: sit:TM1040_3778 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein YP_001542339.1 PFAM: glycosyl transferase family 2; KEGG: rsh:Rsph17029_4080 glycosyl transferase, family 2 YP_001542340.1 PFAM: ABC-2 type transporter; KEGG: rsh:Rsph17029_4086 ABC-2 type transporter YP_001542341.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: mag:amb0878 acetyltransferase YP_001542344.1 PFAM: autoinducer synthesis protein; KEGG: rde:RD1_1639 autoinducer synthesis protein TraL, putative YP_001542345.1 PFAM: beta-lactamase domain protein; KEGG: sil:SPO1523 metallo-beta-lactamase family protein YP_001542346.1 KEGG: sil:SPO1524 hypothetical protein YP_001542347.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; KEGG: acr:Acry_2975 GAF modulated sigma54 specific transcriptional regulator, fis family YP_001542348.1 KEGG: rde:RD1_3706 monooxygenase YP_001542349.2 TIGRFAM: acetoin reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rha:RHA1_ro05279 acetoin dehydrogenase YP_001542350.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bha:BH3949 L-iditol 2-dehydrogenase YP_001542351.1 Converts chlorophyllide a into protochlorophyllide; light dependent YP_001542352.1 PFAM: MltA-interacting MipA family protein; KEGG: reu:Reut_A3319 MltA-interacting MipA YP_001542353.1 PFAM: glycosyl transferase group 1; KEGG: pde:Pden_4362 glycosyl transferase, group 1 YP_001542354.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_0308 binding-protein-dependent transport systems inner membrane component YP_001542355.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: jan:Jann_0307 ABC transporter related YP_001542356.1 PFAM: NMT1/THI5 like domain protein; KEGG: jan:Jann_0306 twin-arginine translocation pathway signal YP_001542357.1 KEGG: jan:Jann_0305 hypothetical protein YP_001542358.1 PFAM: sulfatase; KEGG: jan:Jann_0304 hypothetical protein YP_001542359.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: pde:Pden_4357 CDP-alcohol phosphatidyltransferase YP_001542360.1 PFAM: cytochrome B561; KEGG: jan:Jann_0302 cytochrome b561 YP_001542361.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001542362.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001542363.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: rde:RD1_0248 transcriptional regulator, AraC family YP_001542364.1 KEGG: jan:Jann_1319 hypothetical protein YP_001542365.1 KEGG: jan:Jann_1320 hypothetical protein YP_001542366.2 PFAM: protein of unknown function UPF0118; KEGG: rde:RD1_2476 hypothetical protein YP_001542367.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: eli:ELI_11485 oxidoreductase YP_001542368.1 PFAM: Acetamidase/Formamidase; KEGG: rsh:Rsph17029_3153 acetamidase/formamidase YP_001542369.1 KEGG: rde:RD1_2481 hypothetical protein YP_001542370.1 PFAM: protein of unknown function DUF1469; KEGG: rde:RD1_2479 hypothetical protein YP_001542371.1 KEGG: rde:RD1_2478 hypothetical protein YP_001542372.1 KEGG: jan:Jann_3633 hypothetical protein YP_001542373.1 PFAM: MscS Mechanosensitive ion channel; KEGG: rde:RD1_2453 hypothetical protein YP_001542375.1 PFAM: CsbD family protein; KEGG: jan:Jann_3572 CsbD-like YP_001542376.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: ent:Ent638_0750 GntR domain protein YP_001542377.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02346 ATP-binding ABC transporter protein YP_001542378.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_2078 binding-protein-dependent transport systems inner membrane component YP_001542379.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_2078 binding-protein-dependent transport systems inner membrane component YP_001542380.1 KEGG: mes:Meso_2921 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like YP_001542381.1 KEGG: mac:MA1904 hypothetical protein YP_001542382.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sit:TM1040_3319 TRAP dicarboxylate transporter, DctP subunit YP_001542383.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: bra:BRADO4761 TRAP-type C4-dicarboxylate transport system, fusion of small and large permeases (DctQ/DctM domains) YP_001542384.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: bcl:ABC3355 C4-dicarboxylate transport system permease large protein YP_001542385.1 PFAM: gamma-glutamyltranspeptidase; KEGG: rde:RD1_2179 gamma-glutamyltranspeptidase YP_001542386.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: oih:OB3268 hypothetical protein YP_001542387.1 KEGG: oih:OB3269 hypothetical protein YP_001542388.1 PFAM: conserved hypothetical protein; KEGG: oih:OB3270 hypothetical protein YP_001542389.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pde:Pden_3415 transcriptional regulator, LysR family YP_001542390.1 PFAM: regulatory protein TetR; KEGG: rle:pRL80035 TetR family transcriptional regulator YP_001542391.1 PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: bja:bll6239 probable carbon monoxide dehydrogenase medium chain YP_001542392.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: acr:Acry_2175 (2Fe-2S)-binding domain protein YP_001542393.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: jan:Jann_2947 xanthine dehydrogenase YP_001542394.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: jan:Jann_0870 TRAP dicarboxylate transporter-DctP subunit YP_001542395.1 KEGG: jan:Jann_2036 hypothetical protein YP_001542396.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: jan:Jann_0872 TRAP dicarboxylate transporter-DctM subunit YP_001542397.1 PFAM: aminotransferase class IV; KEGG: jan:Jann_2852 aminotransferase, class IV YP_001542398.1 PFAM: protein of unknown function DUF900 hydrolase family protein; KEGG: rde:RD1_3768 hypothetical protein YP_001542399.1 KEGG: sil:SPO0302 hypothetical protein YP_001542400.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: rde:RD1_0308 glycerophosphoryl diester phosphodiesterase family protein YP_001542401.1 PFAM: PilT protein domain protein; KEGG: gvi:glr1678 plasmid stabilization protein StbB homolog YP_001542402.1 KEGG: gvi:gsr1677 hypothetical protein YP_001542403.1 PFAM: ParB domain protein nuclease; KEGG: rsq:Rsph17025_3691 hypothetical protein YP_001542404.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sit:TM1040_3406 cobyrinic acid a,c-diamide synthase YP_001542405.1 PFAM: initiator RepB protein; KEGG: rsq:Rsph17025_3693 hypothetical protein YP_001542406.1 KEGG: sru:SRU_1591 hypothetical protein YP_001542407.1 PFAM: ABC-1 domain protein; KEGG: rpb:RPB_4322 ABC-1 YP_001542408.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: acr:Acry_2432 alanine racemase YP_001542409.1 PFAM: conserved hypothetical protein; KEGG: bbr:BB4749 hypothetical protein YP_001542411.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: jan:Jann_1159 protein of unknown function DUF112, transmembrane YP_001542412.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rde:RD1_3786 3-hydroxyisobutyrate dehydrogenase YP_001542413.1 KEGG: rde:RD1_0908 hypothetical protein YP_001542414.1 PFAM: Ferritin Dps family protein; KEGG: rde:RD1_0909 hypothetical protein YP_001542415.1 KEGG: rde:RD1_0910 hypothetical protein YP_001542417.2 KEGG: sil:SPO1522 hypothetical protein