-- dump date 20140619_060541 -- class Genbank::CDS -- table cds_note -- id note YP_004254797.1 COGs: COG0593 ATPase involved in DNA replication initiation; HAMAP: Chromosomal replication control, initiator DnaA; InterPro IPR001957:IPR013317:IPR013159:IPR003593; KEGG: dge:Dgeo_0001 chromosomal replication initiation protein; PFAM: Chromosomal replication control, initiator (DnaA)/regulator (Hda); Chromosomal replication initiator, DnaA C-terminal; SMART: Chromosomal replication initiator, DnaA C-terminal; ATPase, AAA+ type, core; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: Chromosomal replication control, initiator DnaA; IMG reference gene:2504121349; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA YP_004254798.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR022634:IPR022637:IPR022635:IPR001001; KEGG: dge:Dgeo_0003 DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain, N-terminal; DNA polymerase III, beta chain, central; DNA polymerase III, beta chain, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain; IMG reference gene:2504121350; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit YP_004254799.1 COGs: COG0148 Enolase; HAMAP: Enolase; InterPro IPR000941:IPR020811:IPR020810; KEGG: ddr:Deide_00030 phosphopyruvate hydratase; PFAM: Enolase, C-terminal; Enolase, N-terminal; PRIAM: Phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: Enolase; IMG reference gene:2504121351; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004254800.1 COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015795:IPR001697; KEGG: dge:Dgeo_0005 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504121352; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase YP_004254801.1 COGs: COG0162 Tyrosyl-tRNA synthetase; HAMAP: Tyrosyl-tRNA synthetase, class Ib; InterPro IPR002307:IPR002305; KEGG: ddr:Deide_00050 tyrosyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; PRIAM: Tyrosine--tRNA ligase; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: Tyrosyl-tRNA synthetase, class Ib; IMG reference gene:2504121353; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_004254802.1 COGs: COG2258 conserved hypothetical protein; InterPro IPR005302; KEGG: dra:DR_0273 hypothetical protein; PFAM: Molybdenum cofactor sulfurase, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504121354; PFAM: MOSC domain YP_004254803.1 InterPro IPR000086; KEGG: dra:DR_0274 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2504121355; PFAM: NUDIX domain YP_004254804.1 COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: dra:DR_0276 hypothetical protein; PFAM: Protein of unknown function DUF633; SPTR: Putative uncharacterized protein; IMG reference gene:2504121356; PFAM: Family of unknown function (DUF633) YP_004254805.1 KEGG: afr:AFE_0040 drug resistance transporter, EmrB/QacA family; SPTR: Drug resistance transporter, EmrB/QacA family; IMG reference gene:2504121357 YP_004254806.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: ddr:Deide_02440 putative LmbE-like protein protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: Putative LmbE-like protein protein; IMG reference gene:2504121358; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: bacillithiol biosynthesis deacetylase BshB1 YP_004254807.1 COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: dra:DR_0237 peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; SPTR: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; IMG reference gene:2504121359; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004254808.1 COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: dge:Dgeo_0208 peptidase M20D, amidohydrolase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: Aminoacylase; SPTR: Peptidase M20D, amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase; IMG reference gene:2504121360; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase YP_004254809.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145:IPR006225; KEGG: dra:DR_1684 pseudouridine synthase, putative; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD; IMG reference gene:2504121361; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_004254810.1 KEGG: atu:Atu0724 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121362 YP_004254811.1 KEGG: dge:Dgeo_1092 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121363 YP_004254812.1 COGs: COG3021 conserved hypothetical protein; InterPro IPR005135; KEGG: dra:DR_2293 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121364; PFAM: Endonuclease/Exonuclease/phosphatase family YP_004254813.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: dge:Dgeo_0146 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 2,4-dienoyl-CoA reductase (NADPH); SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504121365; PFAM: short chain dehydrogenase YP_004254814.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: dra:DR_0114 enoyl-CoA hydratase, putative; PFAM: Crotonase, core; SPTR: Enoyl-CoA hydratase, putative; IMG reference gene:2504121366; PFAM: Enoyl-CoA hydratase/isomerase family YP_004254815.1 COGs: COG2133 Glucose/sorbosone dehydrogenase; KEGG: dge:Dgeo_1002 NHL repeat-containing protein; SPTR: L-sorbosone dehydrogenase; IMG reference gene:2504121367; PFAM: Glucose / Sorbosone dehydrogenase; Membrane bound L-sorbosone dehydrogenase YP_004254816.1 COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; HAMAP: Pyridoxamine kinase; InterPro IPR013749:IPR004625; KEGG: ddr:Deide_01840 pyridoxamine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Pyridoxal kinase; SPTR: Putative Pyridoxamine kinase, (M kinase); TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase; IMG reference gene:2504121368; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase YP_004254817.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: ddr:Deide_22510 putative peptidase M23, precursor; PFAM: Peptidase M23; SPTR: Putative peptidase M23,; IMG reference gene:2504121369; PFAM: Peptidase family M23 YP_004254818.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: dra:DR_0653 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121370; PFAM: Acetyltransferase (GNAT) family YP_004254819.1 COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: dge:Dgeo_2206 thiosulfate sulfurtransferase; PFAM: Rhodanese-like; PRIAM: Thiosulfate sulfurtransferase; SMART: Rhodanese-like; SPTR: Thiosulfate sulfurtransferase; IMG reference gene:2504121371; PFAM: Rhodanese-like domain YP_004254820.1 COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: dra:DR_0216 hypothetical protein; PFAM: Fe-S metabolism associated SufE; SPTR: Putative uncharacterized protein; IMG reference gene:2504121372; PFAM: Fe-S metabolism associated domain YP_004254821.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; HAMAP: Nucleoside-triphosphatase; InterPro IPR020922:IPR002637; KEGG: dge:Dgeo_2209 putative deoxyribonucleotide triphosphate pyrophosphatase; PFAM: Ham1-like protein; PRIAM: Nucleoside-triphosphatase; SPTR: Nucleoside-triphosphatase; TIGRFAM: Ham1-like protein; IMG reference gene:2504121373; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_004254822.1 COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: dge:Dgeo_0147 peptidase S13, D-Ala-D-Ala carboxypeptidase C; PFAM: Peptidase S13, D-Ala-D-Ala carboxypeptidase C; SPTR: Peptidase S13, D-Ala-D-Ala carboxypeptidase C; TIGRFAM: Peptidase S13, D-Ala-D-Ala carboxypeptidase C; IMG reference gene:2504121374; PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family YP_004254823.1 COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: dra:DR_2370 pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component, putative; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504121376; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase YP_004254824.1 COGs: COG4270 membrane protein; KEGG: dra:DR_2024 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121377 YP_004254825.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994; KEGG: dge:Dgeo_2241 peptidase M24; PFAM: Peptidase M24, structural domain; SPTR: Peptidase M24; IMG reference gene:2504121378; PFAM: Metallopeptidase family M24 YP_004254826.1 InterPro IPR011701; KEGG: dge:Dgeo_2304 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504121379; PFAM: Major Facilitator Superfamily YP_004254827.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209:IPR003137; KEGG: dge:Dgeo_2222 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Protease-associated domain, PA; PRIAM: Lactocepin; SPTR: Peptidase S8, subtilisin-like protein; IMG reference gene:2504121380; PFAM: PA domain; Fn3-like domain (DUF1034); Peptidase inhibitor I9; Subtilase family YP_004254828.1 InterPro IPR007280; KEGG: dge:Dgeo_2223 peptidase-like protein; PFAM: Peptidase, C-terminal, archaeal/bacterial; SPTR: PPC, peptidase containing PKD repeats; IMG reference gene:2504121381; PFAM: Bacterial pre-peptidase C-terminal domain YP_004254829.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: dge:Dgeo_2224 peptidase M16-like protein; PFAM: Peptidase M16, N-terminal; Peptidase M16, C-terminal; PRIAM: processing peptidase; SPTR: Peptidase M16-like protein; IMG reference gene:2504121382; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_004254830.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: dge:Dgeo_2225 peptidase M16-like protein; PFAM: Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Peptidase M16-like protein; IMG reference gene:2504121383; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_004254831.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR010723:IPR006638:IPR004559; KEGG: dge:Dgeo_2324 putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM; HemN, C-terminal; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Putative oxygen-independent coproporphyrinogen III oxidase; IMG reference gene:2504121384; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase YP_004254832.1 KEGG: dge:Dgeo_2325 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121385 YP_004254833.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695:IPR006674; KEGG: ddr:Deide_01820 putative exopolyphosphatase, (ExopolyPase), (metaphosphatase), (Ppx/GppA phosphatase); PFAM: Ppx/GppA phosphatase; Metal-dependent phosphohydrolase, HD subdomain; PRIAM: Guanosine-5'-triphosphate,3'-diphosphate diphosphatase; SPTR: Putative Exopolyphosphatase, (ExopolyPase), (Metaphosphatase), (Ppx/GppA phosphatase); IMG reference gene:2504121386; PFAM: HD domain; Ppx/GppA phosphatase family YP_004254834.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dge:Dgeo_2160 glycosyl transferase, group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1; IMG reference gene:2504121387; PFAM: Glycosyl transferases group 1 YP_004254835.1 InterPro IPR002559; KEGG: ddr:Deide_06540 putative transposase; PFAM: Transposase, IS4-like; SPTR: Putative transposase; IMG reference gene:2504121390; PFAM: Transposase DDE domain YP_004254836.1 InterPro IPR002559; KEGG: ddr:Deide_2p00521 putative transposase; PFAM: Transposase, IS4-like; SPTR: Putative transposase; IMG reference gene:2504121391 YP_004254837.1 COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR000589:IPR005290; KEGG: dra:DR_0341 30S ribosomal protein S15; PFAM: Ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: Ribosomal protein S15, bacterial-type; IMG reference gene:2504121394; PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_004254838.1 COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820:IPR023045; KEGG: dge:Dgeo_0338 molybdenum cofactor biosynthesis protein MoaC; PFAM: Molybdopterin cofactor biosynthesis C (MoaC) domain; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdenum cofactor biosynthesis C; IMG reference gene:2504121397; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC YP_004254839.1 COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: ddr:Deide_20550 hypothetical protein; PFAM: Protein of unknown function DUF177; SPTR: Putative uncharacterized protein; IMG reference gene:2504121398; PFAM: Uncharacterized ACR, COG1399 YP_004254840.1 COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005908; KEGG: dra:DR_A0031 glucose-1-phosphate thymidylyltransferase, putative; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate thymidylyltransferase; SPTR: Glucose-1-phosphate thymidylyltransferase, putative; TIGRFAM: Glucose-1-phosphate thymidylyltransferase, short form; IMG reference gene:2504121399; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form YP_004254841.1 KEGG: ddr:Deide_3p01320 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121401 YP_004254842.1 KEGG: dra:DR_0269 hypothetical protein; SPTR: Uncharacterized protein DR_0269; IMG reference gene:2504121402 YP_004254843.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: dra:DR_0865 ferric uptake regulation protein, putative; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulation protein, putative; IMG reference gene:2504121403; PFAM: Ferric uptake regulator family YP_004254844.1 COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: dra:DR_B0133 Na(+)-linked D-alanine glycine permease; PFAM: Sodium:alanine symporter; SPTR: Na(+)-linked D-alanine glycine permease; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2504121404; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_004254845.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; HAMAP: Tetrahydrofolate dehydrogenase/cyclohydrolase; InterPro IPR000672:IPR020630:IPR020631; KEGG: dge:Dgeo_0514 tetrahydrofolate dehydrogenase/cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methylenetetrahydrofolate dehydrogenase (NADP(+)); SPTR: Bifunctional protein folD 1; IMG reference gene:2504121405; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004254846.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); HAMAP: AICARFT/IMPCHase bienzyme; InterPro IPR002695:IPR011607:IPR013982; KEGG: dra:DR_0868 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; Methylglyoxal synthase-like domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; Methylglyoxal synthase-like domain; SPTR: Bifunctional purine biosynthesis protein purH; TIGRFAM: AICARFT/IMPCHase bienzyme; IMG reference gene:2504121406; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_004254847.1 KEGG: ddr:Deide_15980 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121407 YP_004254848.1 COGs: COG0759 conserved hypothetical protein; HAMAP: Protein of unknown function DUF37; InterPro IPR002696; KEGG: dra:DR_2150 hypothetical protein; PFAM: Protein of unknown function DUF37; SPTR: UPF0161 protein DR_2150; TIGRFAM: Protein of unknown function DUF37; IMG reference gene:2504121408; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD YP_004254849.1 COGs: COG0594 RNase P protein component; HAMAP: Ribonuclease P; InterPro IPR000100; KEGG: ddr:Deide_03871 putative ribonuclease P protein component; PFAM: Ribonuclease P; SPTR: Ribonuclease P protein component; IMG reference gene:2504121409; PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_004254850.1 HAMAP: Ribosomal protein L34; InterPro IPR000271; KEGG: dge:Dgeo_1568 50S ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34; IMG reference gene:2504121410; PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type YP_004254851.1 COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: dra:DR_1815 hypothetical protein; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: Putative uncharacterized protein; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; IMG reference gene:2504121411; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_004254852.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789; KEGG: ddr:Deide_17840 putative response regulator, CheY; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Putative response regulator, CheY; IMG reference gene:2504121412; PFAM: Response regulator receiver domain YP_004254853.1 COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: dge:Dgeo_1898 hypothetical protein; PFAM: Protein of unknown function DUF72; SPTR: Putative uncharacterized protein; IMG reference gene:2504121413; PFAM: Protein of unknown function DUF72 YP_004254854.1 COGs: COG3739 Uncharacterized integral membrane protein; InterPro IPR008535; KEGG: bbe:BBR47_22160 hypothetical protein; PFAM: Protein of unknown function DUF817; SPTR: Putative uncharacterized protein; IMG reference gene:2504121414; PFAM: Protein of unknown function (DUF817) YP_004254855.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269:IPR004653; KEGG: dge:Dgeo_1996 tRNA-dihydrouridine synthase A; PFAM: tRNA-dihydrouridine synthase; SPTR: tRNA-dihydrouridine synthase; TIGRFAM: tRNA-dihydrouridine synthase, TIM-barrel, YjbN; IMG reference gene:2504121415; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: tRNA dihydrouridine synthase A YP_004254856.1 InterPro IPR004167; KEGG: ddr:Deide_00370 hypothetical protein; PFAM: E3 binding; SPTR: Putative uncharacterized protein; IMG reference gene:2504121416; PFAM: e3 binding domain YP_004254857.1 COGs: COG0104 Adenylosuccinate synthase; HAMAP: Adenylosuccinate synthetase; InterPro IPR001114; KEGG: ddr:Deide_02690 adenylosuccinate synthetase; PFAM: Adenylosuccinate synthetase; PRIAM: Adenylosuccinate synthase; SMART: Adenylosuccinate synthetase; SPTR: Adenylosuccinate synthetase; IMG reference gene:2504121417; PFAM: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase YP_004254858.1 COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: ddr:Deide_02700 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; IMG reference gene:2504121418; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_004254859.1 COGs: COG4719 conserved hypothetical protein; InterPro IPR001434; KEGG: ddr:Deide_01990 hypothetical protein; PFAM: Domain of unknown function DUF11; SPTR: Putative uncharacterized protein; TIGRFAM: Domain of unknown function DUF11; IMG reference gene:2504121419; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain YP_004254860.1 COGs: COG4867 Uncharacterized protein with a von Willebrand factor type A (vWA) domain; InterPro IPR002035; KEGG: ddr:Deide_02200 hypothetical protein; SMART: von Willebrand factor, type A; SPTR: Putative uncharacterized protein; IMG reference gene:2504121420 YP_004254861.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; HAMAP: 2-thiocytidine tRNA biosynthesis protein, TtcA; InterPro IPR012089:IPR011063; KEGG: ddr:Deide_18460 hypothetical protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase; SPTR: tRNA 2-thiocytidine biosynthesis protein TtcA; IMG reference gene:2504121421; PFAM: PP-loop family YP_004254862.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: ddr:Deide_04040 putative propionyl-CoA carboxylase beta chain, (PCCase), (propanoyl-CoA:carbon dioxide ligase); PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Putative propionyl-CoA carboxylase beta chain, (PCCase), (Propanoyl-CoA:carbon dioxide ligase); IMG reference gene:2504121422; PFAM: Carboxyl transferase domain YP_004254863.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR006059:IPR005673; KEGG: dge:Dgeo_0649 periplasmic phosphate binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: ABC-type phosphate transport system, periplasmic component, PstS; TIGRFAM: Periplasmic phosphate binding protein; IMG reference gene:2504121423; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate ABC transporter, phosphate-binding protein YP_004254864.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: dge:Dgeo_0494 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; PRIAM: Glutamate dehydrogenase (NAD(P)(+)); SMART: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SPTR: Glu/Leu/Phe/Val dehydrogenase; IMG reference gene:2504121424; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004254865.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: ddr:Deide_18260 putative glutamate dehydrogenase (NAD(P)(+)) (glutamate dehydrogenase, GDH); PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; PRIAM: Glutamate dehydrogenase (NAD(P)(+)); SMART: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SPTR: Putative glutamate dehydrogenase (NAD(P)(+)) (Glutamate dehydrogenase, GDH); IMG reference gene:2504121425; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004254866.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dra:DR_0932 polyprenyl synthase; PFAM: Polyprenyl synthetase; PRIAM: Geranyltranstransferase; SPTR: Polyprenyl synthase; IMG reference gene:2504121426; PFAM: Polyprenyl synthetase YP_004254867.1 KEGG: ddr:Deide_18240 hypothetical protein; putative membrane protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121427 YP_004254868.1 COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR000241; KEGG: ddr:Deide_03840 putative N6-adenine-specific DNA methylase; putative RNA methylase; PFAM: Putative RNA methylase; SPTR: Putative N6-adenine-specific DNA methylase; putative RNA methylase; IMG reference gene:2504121428; PFAM: Putative RNA methylase family UPF0020 YP_004254869.1 COGs: COG2847 conserved hypothetical protein; InterPro IPR007410; KEGG: dra:DR_1885 hypothetical protein; PFAM: DR1885-like metal-binding protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121429; PFAM: Protein of unknown function (DUF461) YP_004254870.1 COGs: COG1999 Uncharacterized protein SCO1/SenC/PrrC involved in biogenesis of respiratory and photosynthetic systems; InterPro IPR003782; KEGG: dge:Dgeo_0582 electron transport protein SCO1/SenC; PFAM: Copper chaperone SCO1/SenC; SPTR: Electron transport protein SCO1/SenC; IMG reference gene:2504121430; PFAM: SCO1/SenC YP_004254871.1 COGs: COG3336 membrane protein; InterPro IPR019108; KEGG: dge:Dgeo_0583 membrane protein; PFAM: Cytochrome c oxidase caa3-type, assembly factor CtaG-related; SPTR: Membrane protein; IMG reference gene:2504121431; PFAM: Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) YP_004254872.1 KEGG: ddr:Deide_04602 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121432 YP_004254873.1 COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: dge:Dgeo_1100 DegV family protein; PFAM: DegV; SPTR: DegV family protein; TIGRFAM: DegV; IMG reference gene:2504121433; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family YP_004254874.1 COGs: COG3339 conserved hypothetical protein; InterPro IPR010652; KEGG: rxy:Rxyl_0592 hypothetical protein; PFAM: Protein of unknown function DUF1232; SPTR: Putative uncharacterized protein; IMG reference gene:2504121434; PFAM: Protein of unknown function (DUF1232) YP_004254875.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: dra:DR_0784 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2504121435; PFAM: NUDIX domain YP_004254876.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR004365:IPR003141:IPR 004805; KEGG: ddr:Deide_21950 putative DNA-directed DNA polymerase (DNA polymerase III, alpha subunit); PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: Putative DNA-directed DNA polymerase (DNA polymerase III, alpha subunit); TIGRFAM: DNA polymerase III, alpha subunit; IMG reference gene:2504121437; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004254877.1 IMG reference gene:2504121438 YP_004254878.1 KEGG: ddr:Deide_1p00110 hypothetical protein; putative membrane protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504121439 YP_004254879.1 COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: ddr:Deide_21941 hypothetical protein; PFAM: Protein of unknown function DUF72; SPTR: Putative uncharacterized protein; IMG reference gene:2504121440; PFAM: Protein of unknown function DUF72 YP_004254880.1 COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; HAMAP: Queuine tRNA-ribosyltransferase; InterPro IPR004803:IPR002616; KEGG: dge:Dgeo_0330 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: Queuine tRNA-ribosyltransferase; Queuine/other tRNA-ribosyltransferase; manually curated; IMG reference gene:2504121444; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming YP_004254881.1 InterPro IPR001119; KEGG: dge:Dgeo_0331 S-layer-like protein region; PFAM: S-layer homology domain; SPTR: S-layer-like protein region; IMG reference gene:2504121445; PFAM: S-layer homology domain YP_004254882.1 COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR001667:IPR004097; KEGG: dge:Dgeo_0332 putative manganese-dependent inorganic pyrophosphatase; PFAM: DHHA2; Phosphoesterase, RecJ-like; PRIAM: Inorganic diphosphatase; SPTR: Inorganic diphosphatase; IMG reference gene:2504121446; PFAM: DHH family; DHHA2 domain YP_004254883.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR004101:IPR001645; KEGG: dge:Dgeo_0333 FolC bifunctional protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; IMG reference gene:2504121447; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004254884.1 KEGG: dge:Dgeo_0335 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121448 YP_004254885.1 InterPro IPR001387; KEGG: dge:Dgeo_0336 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, HTH_3 family; IMG reference gene:2504121449; PFAM: Helix-turn-helix YP_004254886.1 KEGG: dge:Dgeo_0337 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121450 YP_004254887.1 KEGG: dgr:Dgri_GH21334 GH21334 gene product from transcript GH21334-RA; IMG reference gene:2504121451 YP_004254888.1 COGs: COG3404 Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR007044; KEGG: ddr:Deide_20220 putative methenyltetrahydrofolate cyclohydrolase; PFAM: Cyclodeaminase/cyclohydrolase; SPTR: Putative methenyltetrahydrofolate cyclohydrolase; IMG reference gene:2504121452; PFAM: Formiminotransferase-cyclodeaminase YP_004254889.1 COGs: COG0039 Malate/lactate dehydrogenase; HAMAP: Malate dehydrogenase; InterPro IPR001236:IPR022383:IPR010945; KEGG: ddr:Deide_20240 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; SPTR: Malate dehydrogenase; TIGRFAM: Malate dehydrogenase, NAD/NADP; IMG reference gene:2504121453; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase; malate dehydrogenase, NAD-dependent YP_004254890.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterPro IPR005259; KEGG: dge:Dgeo_0271 primosomal protein N'; SPTR: Primosomal protein N'; TIGRFAM: Primosomal protein n; IMG reference gene:2504121454; TIGRFAM: primosomal protein N' YP_004254891.1 COGs: COG2354 conserved hypothetical protein; InterPro IPR008526; KEGG: dra:DR_1297 hypothetical protein; PFAM: Protein of unknown function DUF808; SPTR: Putative uncharacterized protein; IMG reference gene:2504121455; PFAM: Protein of unknown function (DUF808) YP_004254892.1 InterPro IPR007272; KEGG: dra:DR_A0163 hypothetical protein; PFAM: Domain of unknown function DUF395, YeeE/YedE; SPTR: Putative uncharacterized protein; IMG reference gene:2504121456; PFAM: YeeE/YedE family (DUF395) YP_004254893.1 InterPro IPR007272; KEGG: dge:Dgeo_2678 protein of unknown function DUF395, YeeE/YedE; PFAM: Domain of unknown function DUF395, YeeE/YedE; SPTR: Putative uncharacterized protein; IMG reference gene:2504121457; PFAM: YeeE/YedE family (DUF395) YP_004254894.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: msv:Mesil_2628 protein of unknown function DUF81; PFAM: Protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2504121458; PFAM: Sulfite exporter TauE/SafE YP_004254895.1 InterPro IPR013217; KEGG: rme:Rmet_4066 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Putative uncharacterized protein; IMG reference gene:2504121459 YP_004254896.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279:IPR001763; KEGG: dra:DR_A0304 hypothetical protein; PFAM: Beta-lactamase-like; Rhodanese-like; SMART: Beta-lactamase-like; Rhodanese-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504121460; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain YP_004254897.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: msv:Mesil_2633 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; IMG reference gene:2504121461; PFAM: Rhodanese-like domain YP_004254898.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: dra:DR_A0156 hypothetical protein; PFAM: Protein of unknown function DUF156; SPTR: Putative uncharacterized protein; IMG reference gene:2504121462; PFAM: Uncharacterised BCR, COG1937 YP_004254899.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: dra:DR_1101 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; IMG reference gene:2504121463; PFAM: Methyltransferase domain YP_004254900.1 KEGG: scl:sce5151 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121464 YP_004254901.1 InterPro IPR004843; KEGG: ddr:Deide_19310 putative metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Putative metallophosphoesterase; IMG reference gene:2504121465; PFAM: Calcineurin-like phosphoesterase YP_004254902.1 KEGG: ddr:Deide_19300 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121466 YP_004254903.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005835; KEGG: dra:DR_1824 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: Glucose-1-phosphate adenylyltransferase; IMG reference gene:2504121468; PFAM: Nucleotidyl transferase YP_004254904.1 KEGG: dra:DR_0600 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121469 YP_004254905.1 HAMAP: Ribosomal protein L28; InterPro IPR001383; KEGG: dra:DR_2524 50S ribosomal protein L28; PFAM: Ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: Ribosomal protein L28; IMG reference gene:2504121470; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_004254906.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: ddr:Deide_07330 putative metal ABC transporter, periplasmic component; PFAM: ABC transporter metal-binding lipoprotein; SPTR: Putative metal ABC transporter, periplasmic component; manually curated; IMG reference gene:2504121471; PFAM: Periplasmic solute binding protein family YP_004254907.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dge:Dgeo_0533 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type Mn2+ transport system, ATPase component; IMG reference gene:2504121472; PFAM: ABC transporter YP_004254908.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: dra:DR_2283 manganese ABC transporter, permease protein, putative; PFAM: ABC-3; SPTR: Manganese ABC transporter, permease protein, putative; IMG reference gene:2504121473; PFAM: ABC 3 transport family YP_004254909.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; HAMAP: Uncharacterised protein family UPF0173, metal-dependent hydrolase; InterPro IPR022877:IPR001279; KEGG: ddr:Deide_19690 metal-dependent hydrolase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: UPF0173 metal-dependent hydrolase Deide_19690; IMG reference gene:2504121474; PFAM: Metallo-beta-lactamase superfamily YP_004254910.1 KEGG: dge:Dgeo_0421 hypothetical protein; SPTR: Zn-finger containing protein; IMG reference gene:2504121475 YP_004254911.1 KEGG: dra:DR_0582 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121476 YP_004254912.1 KEGG: dra:DR_1231 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121477 YP_004254913.1 InterPro IPR012902; KEGG: dra:DR_1232 pilin, type IV, putative; SPTR: Pilin, type IV, putative; manually curated; IMG reference gene:2504121478; PFAM: Prokaryotic N-terminal methylation motif; Type II transport protein GspH; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; Verrucomicrobium spinosum paralogous family TIGR02596 YP_004254914.1 InterPro IPR012902; KEGG: dge:Dgeo_2110 putative pilin, type IV; SPTR: Putative pilin, type IV; manually curated; IMG reference gene:2504121479; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004254915.1 InterPro IPR012902; KEGG: dra:DR_1234 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121480 YP_004254916.1 COGs: COG1160 GTPase; InterPro IPR001401; KEGG: dge:Dgeo_2106 dynamin; PFAM: Dynamin, GTPase domain; SPTR: Dynamin-like GTPase; IMG reference gene:2504121481; PFAM: Dynamin family; TIGRFAM: small GTP-binding protein domain YP_004254917.1 COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: dge:Dgeo_0190 IclR family transcriptional regulator; PFAM: Transcription regulator IclR, N-terminal; Transcription regulator IclR, C-terminal; SMART: Transcription regulator IclR, N-terminal; SPTR: Transcriptional regulator, IclR family; IMG reference gene:2504121482; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004254918.1 COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: dra:DR_2238 carbonic anhydrase; PFAM: Carbonic anhydrase; SMART: Carbonic anhydrase; SPTR: Carbonic anhydrase; IMG reference gene:2504121483; PFAM: Carbonic anhydrase YP_004254919.1 KEGG: dge:Dgeo_2192 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121484 YP_004254920.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ddr:Deide_19810 putative histidine kinase, classic; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Putative histidine kinase, classic; IMG reference gene:2504121485; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004254921.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dra:DR_2245 phosphate regulon transcriptional regulatory protein PhoB; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Phosphate regulon transcriptional regulatory protein PhoB; IMG reference gene:2504121486; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004254922.1 COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: dge:Dgeo_0131 iojap-related protein; PFAM: Ribosome-associated, Iojap-like; SPTR: Iojap-related protein; TIGRFAM: Ribosome-associated, Iojap-like; IMG reference gene:2504121487; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein YP_004254923.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dge:Dgeo_0132 cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504121488; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004254924.1 COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR006674:IPR003607:IPR005249; KEGG: dge:Dgeo_0133 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; IMG reference gene:2504121489; PFAM: HD domain; TIGRFAM: putative HD superfamily hydrolase of NAD metabolism YP_004254925.1 COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: dge:Dgeo_0134 YbbR-like protein; PFAM: YbbR-like; SPTR: YbbR-like protein; IMG reference gene:2504121490; PFAM: YbbR-like protein YP_004254926.1 COGs: COG1624 conserved hypothetical protein; InterPro IPR003390:IPR014046; KEGG: ddr:Deide_19700 hypothetical protein; PFAM: DNA integrity scanning protein, DisA, N-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00159; IMG reference gene:2504121491; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: TIGR00159 family protein YP_004254927.1 COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR019304:IPR006124; KEGG: ddr:Deide_22650 cofactor-independent phosphoglycerate mutase; PFAM: Bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme; PRIAM: Phosphoglycerate mutase; SPTR: Putative Phosphoglycerate mutase (Phosphoglycerate phosphomutase) (Phosphoglyceromutase) (PGAM); IMG reference gene:2504121492; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme superfamily; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal form YP_004254928.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: ddr:Deide_22670 putative tRNA guanosine-2-O-methyltransferase (transfer ribonucleate guanosine 2-methyltransferase); PFAM: tRNA/rRNA methyltransferase, SpoU; PRIAM: tRNA guanosine-2'-O-methyltransferase; SPTR: Putative tRNA guanosine-2-O-methyltransferase (Transfer ribonucleate guanosine 2-methyltransferase); IMG reference gene:2504121494; PFAM: SpoU rRNA Methylase family; SpoU, rRNA methylase, C-terminal YP_004254929.1 KEGG: rop:ROP_26170 hypothetical protein; SPTR: MtrX; IMG reference gene:2504121495 YP_004254930.1 KEGG: dra:DR_1458 hypothetical protein; SPTR: Probable RNA 2'-phosphotransferase; IMG reference gene:2504121496 YP_004254931.1 KEGG: dra:DR_2425 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121497 YP_004254932.1 KEGG: xca:xccb100_3834 D-amino acid dehydrogenase small subunit; SPTR: Beta-galactosidase; IMG reference gene:2504121498 YP_004254933.1 COGs: COG2860 membrane protein; InterPro IPR005115; KEGG: dge:Dgeo_0012 hypothetical protein; PFAM: Uncharacterised protein family UPF0126; SPTR: Conserved membrane protein UPF0126; IMG reference gene:2504121499; PFAM: UPF0126 domain YP_004254934.1 COGs: COG0217 conserved hypothetical protein; HAMAP: Protein of unknown function DUF28; InterPro IPR002876; KEGG: dge:Dgeo_2194 hypothetical protein; PFAM: Protein of unknown function DUF28; SPTR: UPF0082 protein Dgeo_2194; TIGRFAM: Protein of unknown function DUF28; IMG reference gene:2504121500; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family YP_004254935.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: dra:DR_2549 epoxide hydrolase-related protein; PFAM: Alpha/beta hydrolase fold-1; PRIAM: Soluble epoxide hydrolase; SPTR: Epoxide hydrolase-related protein; IMG reference gene:2504121501; PFAM: alpha/beta hydrolase fold YP_004254936.1 KEGG: dge:Dgeo_0191 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121502 YP_004254937.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: dge:Dgeo_0193 alpha/beta hydrolase fold; PFAM: Alpha/beta hydrolase fold-1; SPTR: Alpha/beta hydrolase fold; IMG reference gene:2504121503; PFAM: alpha/beta hydrolase fold YP_004254938.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dge:Dgeo_0195 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2504121504; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004254939.1 COGs: COG3191 L-aminopeptidase/D-esterase; InterPro IPR005321; KEGG: dra:DR_0782 hypothetical protein; PFAM: Peptidase S58, DmpA; SPTR: Putative uncharacterized protein; IMG reference gene:2504121505; PFAM: Peptidase family S58 YP_004254940.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209; KEGG: dra:DR_1459 serine protease; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; PRIAM: Subtilisin; SPTR: Serine protease, subtilase family; IMG reference gene:2504121506; PFAM: Subtilase family YP_004254941.1 COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: ddr:Deide_21600 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: Putative uncharacterized protein; IMG reference gene:2504121507; PFAM: Uncharacterized protein family UPF0027 YP_004254942.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683:IPR003736; KEGG: dra:DR_2406 ComA protein; PFAM: Thioesterase superfamily; SPTR: Putative esterase DR_2406; TIGRFAM: Phenylacetic acid degradation-related protein; IMG reference gene:2504121508; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_004254943.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: dra:DR_0089 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: Putative uncharacterized protein; IMG reference gene:2504121510; PFAM: Glycosyl transferase family 2 YP_004254944.1 InterPro IPR007341; KEGG: dge:Dgeo_2251 transglycosylase-associated protein; PFAM: Transglycosylase-associated protein; SPTR: Transglycosylase-associated protein; IMG reference gene:2504121511; PFAM: Transglycosylase associated protein YP_004254945.1 COGs: COG0083 Homoserine kinase; HAMAP: Homoserine kinase; InterPro IPR000870:IPR006204:IPR013750; KEGG: dge:Dgeo_2253 homoserine kinase; PFAM: GHMP kinase; GHMP kinase, C-terminal; SPTR: Homoserine kinase; TIGRFAM: Homoserine kinase; IMG reference gene:2504121512; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: homoserine kinase YP_004254946.1 COGs: COG0597 Lipoprotein signal peptidase; HAMAP: Peptidase A8, signal peptidase II; InterPro IPR001872; KEGG: ddr:Deide_01290 lipoprotein signal peptidase; PFAM: Peptidase A8, signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: Peptidase A8, signal peptidase II; IMG reference gene:2504121513; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_004254947.1 KEGG: ddr:Deide_20710 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121514 YP_004254948.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dge:Dgeo_0315 two component LuxR family transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504121515; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004254949.1 InterPro IPR003088; KEGG: dge:Dgeo_0317 cytochrome c, class I; PFAM: Cytochrome c, class I; SPTR: Cytochrome c, class I; IMG reference gene:2504121516; PFAM: Cytochrome c YP_004254950.1 COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941; KEGG: dge:Dgeo_0318 Rieske (2Fe-2S) region; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske (2Fe-2S) region; IMG reference gene:2504121517; PFAM: Rieske [2Fe-2S] domain YP_004254951.1 COGs: COG1290 Cytochrome b subunit of the bc complex; InterPro IPR005797; KEGG: ddr:Deide_20650 putative cytochrome b/b6; putative membrane protein; PFAM: Cytochrome b/b6, N-terminal; SPTR: Putative cytochrome b/b6; putative membrane protein; IMG reference gene:2504121518 YP_004254952.1 COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: dge:Dgeo_0412 magnesium protoporphyrin chelatase, putative; SPTR: Magnesium protoporphyrin chelatase, AAA class ATPase; IMG reference gene:2504121519; PFAM: Sigma-54 interaction domain YP_004254953.1 KEGG: dge:Dgeo_0492 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121524 YP_004254954.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524:IPR004839; KEGG: rxy:Rxyl_0136 GntR family transcriptional regulator; PFAM: HTH transcriptional regulator, GntR; Aminotransferase, class I/classII; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family; IMG reference gene:2504121525; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II YP_004254955.1 COGs: COG0214 Pyridoxine biosynthesis enzyme; HAMAP: Vitamin B6 biosynthesis protein; InterPro IPR001852; KEGG: dge:Dgeo_1106 pyridoxal biosynthesis lyase PdxS; PFAM: Vitamin B6 biosynthesis protein; SPTR: Pyridoxal biosynthesis lyase pdxS; TIGRFAM: Vitamin B6 biosynthesis protein; IMG reference gene:2504121526; PFAM: SOR/SNZ family; TIGRFAM: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 YP_004254956.1 COGs: COG0311 glutamine amidotransferase involved in pyridoxine biosynthesis; HAMAP: Glutamine amidotransferase subunit PdxT; InterPro IPR002161; KEGG: ddr:Deide_11600 glutamine amidotransferase subunit PdxT; PFAM: Glutamine amidotransferase subunit PdxT; SPTR: Glutamine amidotransferase subunit pdxT; TIGRFAM: Glutamine amidotransferase subunit PdxT; IMG reference gene:2504121527; PFAM: SNO glutamine amidotransferase family; TIGRFAM: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 YP_004254957.1 COGs: COG2262 GTPase; InterPro IPR002917:IPR016496; KEGG: dge:Dgeo_2006 GTP-binding protein, HSR1-related; PFAM: GTP-binding protein, HSR1-related; SPTR: GTP-binding protein, HSR1-related; TIGRFAM: GTP-binding protein, HflX; manually curated; IMG reference gene:2504121528; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX; small GTP-binding protein domain YP_004254958.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; HAMAP:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di aminopimelateligase; InterPro IPR005761:IPR000713:IPR013221:IPR004101; KEGG: dra:DR_0297 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelateligase; SPTR: UDP-N-acetylmuramyl-tripeptide synthetase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelateligase; IMG reference gene:2504121531; PFAM: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase YP_004254959.1 COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: dge:Dgeo_1945 peptidylprolyl isomerase, FKBP-type; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504121532; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004254960.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR005111:IPR020817; KEGG: dge:Dgeo_1944 MoeA-like protein; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; SMART: Molybdopterin binding; SPTR: MoeA-like protein, domain I and II; TIGRFAM: Molybdenum cofactor synthesis; IMG reference gene:2504121533; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain YP_004254961.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterProIPR020822:IPR006218:IPR002701:IPR010954:IPR 006268; KEGG: dge:Dgeo_1572 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; SMART: Chorismate mutase; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; Chorismate mutase, Gram-positive bacteria/Deinococcus; IMG reference gene:2504121534; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; chorismate mutase domain of gram positive AroA protein YP_004254962.1 KEGG: dge:Dgeo_1571 hypothetical protein; SPTR: RNA ligase of LigT family; IMG reference gene:2504121535 YP_004254963.1 COGs: COG2345 transcriptional regulator protein; InterPro IPR001845; KEGG: dge:Dgeo_1570 putative transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SPTR: Putative transcriptional regulator; IMG reference gene:2504121536; PFAM: Bacterial regulatory protein, arsR family YP_004254964.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR002744:IPR019591; KEGG: dra:DR_0998 mrp protein; PFAM: ATPase-like, ParA/MinD; Domain of unknown function DUF59; SPTR: Protein mrp homolog; IMG reference gene:2504121537; PFAM: ParA/MinD ATPase like; Domain of unknown function DUF59 YP_004254965.1 COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0122 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; PRIAM: Peroxiredoxin; SPTR: Thiol-specific antioxidant protein, putative; IMG reference gene:2504121538; PFAM: AhpC/TSA family YP_004254966.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370:IPR014047; KEGG: dge:Dgeo_0120 chromate transporter; PFAM: Chromate transporter; SPTR: Chromate transporter; TIGRFAM: Chromate transporter, long chain; IMG reference gene:2504121539; PFAM: Chromate transporter; TIGRFAM: chromate transporter, chromate ion transporter (CHR) family YP_004254967.1 InterPro IPR002121; KEGG: dra:DR_2444 HRDC family nucleic acid-binding protein; PFAM: Helicase/RNase D C-terminal, HRDC domain; SMART: Helicase/RNase D C-terminal, HRDC domain; SPTR: Nucleic acid-binding protein, putative, HRDC family; IMG reference gene:2504121540; PFAM: HRDC domain YP_004254968.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dge:Dgeo_1041 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, family 2; IMG reference gene:2504121541; PFAM: Glycosyl transferase family 2 YP_004254969.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: dge:Dgeo_0254 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: Cell wall hydrolase/autolysin; IMG reference gene:2504121542; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004254970.1 InterPro IPR000182; KEGG: ddr:Deide_02930 putative GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative GCN5-related N-acetyltransferase; IMG reference gene:2504121543; PFAM: Acetyltransferase (GNAT) family YP_004254971.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269; KEGG: dge:Dgeo_0077 dihydrouridine synthase, DuS; PFAM: tRNA-dihydrouridine synthase; SPTR: Dihydrouridine synthase, DuS; IMG reference gene:2504121544; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: putative TIM-barrel protein, nifR3 family YP_004254972.1 COGs: COG2378 transcriptional regulator protein; InterPro IPR013196; KEGG: ddr:Deide_01080 putative transcriptional regulator; SPTR: Putative transcriptional regulator; IMG reference gene:2504121545; PFAM: HTH domain YP_004254973.1 COGs: COG1416 conserved hypothetical protein; KEGG: dra:DR_0054 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121546; PFAM: DsrE/DsrF-like family YP_004254974.1 COGs: COG2318 conserved hypothetical protein; InterPro IPR007837; KEGG: dra:DR_0053 hypothetical protein; PFAM: DinB; SPTR: Putative uncharacterized protein; IMG reference gene:2504121547; PFAM: DinB family YP_004254975.1 COGs: COG2318 conserved hypothetical protein; InterPro IPR007837; KEGG: dra:DR_0050 hypothetical protein; PFAM: DinB; SPTR: Putative uncharacterized protein; IMG reference gene:2504121548; PFAM: DinB family YP_004254976.1 COGs: COG0181 Porphobilinogen deaminase; HAMAP: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; InterPro IPR000860:IPR022417:IPR022418; KEGG: ddr:Deide_01510 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, N-terminal; Porphobilinogen deaminase, C-terminal domain; SPTR: Porphobilinogen deaminase; TIGRFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; IMG reference gene:2504121549; PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase YP_004254977.1 COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: dge:Dgeo_0094 asparaginase/glutaminase; PFAM: Asparaginase/glutaminase; PRIAM: Asparaginase; SMART: Asparaginase/glutaminase; SPTR: Asparaginase/glutaminase; IMG reference gene:2504121550; PFAM: Asparaginase YP_004254978.1 KEGG: dra:DR_2182 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121551 YP_004254979.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130:IPR015991; KEGG: dge:Dgeo_0151 TatD-related deoxyribonuclease; PFAM: Deoxyribonuclease, TatD-related; SPTR: TatD-related deoxyribonuclease; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504121552; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_004254980.1 COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: SAICAR synthetase; InterPro IPR001636; KEGG: dra:DR_0226 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase; IMG reference gene:2504121553; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004254981.1 COGs: COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase PurS component; InterPro IPR003850; KEGG: dra:DR_0224 hypothetical protein; PFAM: Phosphoribosylformylglycinamidine synthetase, PurS subunit; SPTR: Putative uncharacterized protein; TIGRFAM: Phosphoribosylformylglycinamidine synthetase, PurS subunit; IMG reference gene:2504121554; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein YP_004254982.1 COGs: COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain; HAMAP: Phosphoribosylformylglycinamidine synthase I; InterPro IPR010075:IPR011698; KEGG: dra:DR_0223 phosphoribosylformylglycinamidine synthase I; PFAM: CobB/CobQ-like glutamine amidotransferase; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase 1; TIGRFAM: Phosphoribosylformylglycinamidine synthase I; IMG reference gene:2504121555; PFAM: CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: phosphoribosylformylglycinamidine synthase I YP_004254983.1 COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; HAMAP: Phosphoribosylformylglycinamidine synthase II; InterPro IPR010074:IPR000728:IPR010918; KEGG: dge:Dgeo_0064 phosphoribosylformylglycinamidine synthase II; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase 2; TIGRFAM: Phosphoribosylformylglycinamidine synthase II; IMG reference gene:2504121556; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase II YP_004254984.1 COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583:IPR000836:IPR005854; KEGG: ddr:Deide_21330 putative amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; Phosphoribosyltransferase; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: Amidophosphoribosyl transferase; IMG reference gene:2504121557; PFAM: Phosphoribosyl transferase domain; Glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase YP_004254985.1 KEGG: rcu:RCOM_0096200 ARP2/3 complex 34 kDa subunit, putative; SPTR: DNA primase; IMG reference gene:2504121558 YP_004254986.1 KEGG: vvi:100249841 hypothetical protein LOC100249841; SPTR: Putative uncharacterized protein; IMG reference gene:2504121559 YP_004254987.1 COGs: COG0717 Deoxycytidine deaminase; InterPro IPR011962; KEGG: mab:MAB_4867c dCTP deaminase/DeoxyUTP pyrophosphatase; SPTR: dCTP deaminase; TIGRFAM: Deoxycytidine triphosphate deaminase; IMG reference gene:2504121560; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase YP_004254988.1 COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: dra:DR_0662 hypothetical protein; PFAM: PemK-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121561; PFAM: PemK-like protein YP_004254989.1 KEGG: dra:DR_0661 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121562 YP_004254990.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: dra:DR_2564 hypothetical protein; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1; SPTR: Putative uncharacterized protein; IMG reference gene:2504121563; PFAM: Phosphoglycerate mutase family YP_004254991.1 KEGG: ddr:Deide_21340 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121564 YP_004254992.1 COGs: COG0861 Membrane protein TerC possibly involved in tellurium resistance; InterPro IPR005496; KEGG: dra:DR_B0131 hypothetical protein; PFAM: Integral membrane protein TerC; SPTR: Putative uncharacterized protein; IMG reference gene:2504121565; PFAM: Integral membrane protein TerC family YP_004254993.1 InterPro IPR003088; KEGG: dge:Dgeo_0018 cytochrome c, class I; PFAM: Cytochrome c, class I; SPTR: Cytochrome c, class I; IMG reference gene:2504121566; PFAM: Cytochrome c YP_004254994.1 COGs: COG0843 Heme/copper-type cytochrome/quinol oxidase subunit 1; InterPro IPR000883; KEGG: dge:Dgeo_0017 cytochrome c oxidase, subunit I; PFAM: Cytochrome c oxidase, subunit I; PRIAM: Cytochrome-c oxidase; SPTR: Cytochrome c oxidase, subunit I; IMG reference gene:2504121567; PFAM: Cytochrome C and Quinol oxidase polypeptide I YP_004254995.1 COGs: COG1622 Heme/copper-type cytochrome/quinol oxidase subunit 2; InterPro IPR002429; KEGG: dge:Dgeo_0016 cytochrome c oxidase, subunit II; PFAM: Cytochrome c oxidase subunit II C-terminal; SPTR: Cytochrome c oxidase, subunit II; IMG reference gene:2504121568; PFAM: Cytochrome C oxidase subunit II, periplasmic domain YP_004254996.1 KEGG: dan:Dana_GF24314 GF24314 gene product from transcript GF24314-RA; SPTR: GF24314; IMG reference gene:2504121569 YP_004254997.1 COGs: COG0793 Periplasmic protease; InterPro IPR005151:IPR001478; KEGG: dra:DR_1308 protease, putative; PFAM: Peptidase S41; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: Protease, putative; IMG reference gene:2504121570; PFAM: Peptidase family S41 YP_004254998.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: ddr:Deide_21220 putative major facilitator superfamily protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative Major Facilitator Superfamily protein; IMG reference gene:2504121571; PFAM: Major Facilitator Superfamily YP_004254999.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478; KEGG: dge:Dgeo_2025 peptidase S1 and S6, chymotrypsin/Hap; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: Peptidase S1 and S6, chymotrypsin/Hap; IMG reference gene:2504121572; PFAM: Trypsin YP_004255000.1 KEGG: dge:Dgeo_2024 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121573 YP_004255001.1 COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537:IPR004441; KEGG: dra:DR_0748 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SMART: RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase, TrmH family; TIGRFAM: RNA methyltransferase TrmH, group 3; IMG reference gene:2504121574; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3 YP_004255002.1 COGs: COG2200 FOG: EAL domain; InterProIPR013656:IPR013767:IPR000160:IPR001633:IPR 000014; KEGG: ddr:Deide_04860 putative signal transduction protein: sensor, PAS/PAC domains; regulator, GGDEF/EAL domains; PFAM: Diguanylate phosphodiesterase, EAL domain; PAS fold-4; PAS fold; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; SPTR: Sensory box/GGDEF family protein; TIGRFAM: PAS; IMG reference gene:2504121575; PFAM: EAL domain; GGDEF domain; PAS fold YP_004255003.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: dge:Dgeo_2084 aminotransferase, class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Aromatic-amino-acid transaminase; SPTR: Aminotransferase; IMG reference gene:2504121576; PFAM: Aminotransferase class I and II YP_004255004.1 COGs: COG1485 ATPase; InterPro IPR005654:IPR003593; KEGG: dge:Dgeo_2019 AFG1-like protein ATPase; PFAM: ATPase, AFG1-like; SMART: ATPase, AAA+ type, core; SPTR: AFG1-like protein ATPase; IMG reference gene:2504121577; PFAM: AFG1-like ATPase YP_004255005.1 COGs: COG2302 conserved hypothetical protein contains S4-like domain; InterPro IPR002942; KEGG: dra:DR_0787 hypothetical protein; PFAM: RNA-binding S4; SPTR: Putative uncharacterized protein; IMG reference gene:2504121578; PFAM: S4 domain YP_004255006.1 KEGG: ddr:Deide_00710 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121579 YP_004255007.1 COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: dge:Dgeo_2063 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504121580; PFAM: Acetyltransferase (GNAT) family YP_004255008.1 COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474:IPR000991:IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; IMG reference gene:2504121581; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_004255009.1 InterPro IPR001434; KEGG: dra:DR_0685 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Domain of unknown function DUF11; IMG reference gene:2504121582 YP_004255010.1 InterPro IPR001434; KEGG: dge:Dgeo_0310 hypothetical protein; PFAM: Domain of unknown function DUF11; SPTR: Putative uncharacterized protein; TIGRFAM: Domain of unknown function DUF11; IMG reference gene:2504121583; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain YP_004255011.1 KEGG: ddr:Deide_02020 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121584 YP_004255012.1 InterPro IPR001434; KEGG: dra:DR_0145 hypothetical protein; PFAM: Domain of unknown function DUF11; SPTR: Putative uncharacterized protein; TIGRFAM: Domain of unknown function DUF11; IMG reference gene:2504121585; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain YP_004255013.1 KEGG: ddr:Deide_00870 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121586 YP_004255014.1 COGs: COG0193 Peptidyl-tRNA hydrolase; HAMAP: Peptidyl-tRNA hydrolase; InterPro IPR001328; KEGG: dra:DR_2372 peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: Peptidyl-tRNA hydrolase; IMG reference gene:2504121587; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_004255015.1 KEGG: ddr:Deide_00900 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121588 YP_004255016.1 KEGG: ddr:Deide_00930 putative vacuolar type ATP synthase subunit; SPTR: Putative Vacuolar type ATP synthase subunit; IMG reference gene:2504121589 YP_004255017.1 COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: ddr:Deide_00940 putative V-type ATP synthase subunit I; putative membrane protein; PFAM: ATPase, V0/A0 complex, 116kDa subunit; SPTR: Putative V-type ATP synthase subunit I; putative membrane protein; IMG reference gene:2504121590; PFAM: V-type ATPase 116kDa subunit family YP_004255018.1 InterPro IPR002379; KEGG: dra:DR_0696 v-type ATP synthase, K subunit; PFAM: ATPase, F0/V0 complex, subunit C; SPTR: V-type ATP synthase, K subunit; IMG reference gene:2504121591; PFAM: ATP synthase subunit C YP_004255019.1 COGs: COG1390 H+-ATPase subunit E; HAMAP: ATPase, V1/A1 complex, subunit E; InterPro IPR002842; KEGG: dge:Dgeo_2050 H+-transporting two-sector ATPase, E subunit; PFAM: ATPase, V1/A1 complex, subunit E; SPTR: V-type ATP synthase subunit E; IMG reference gene:2504121592; PFAM: ATP synthase (E/31 kDa) subunit YP_004255020.1 COGs: COG1527 H+-ATPase subunit C; HAMAP: ATPase, A1 complex, subunit C; InterPro IPR014272:IPR002843; KEGG: dge:Dgeo_2049 H+-transporting two-sector ATPase, C (AC39) subunit; PFAM: ATPase, V0/A0 complex, subunit C/D; SPTR: V-type ATP synthase subunit C; IMG reference gene:2504121593; PFAM: ATP synthase (C/AC39) subunit YP_004255021.1 InterPro IPR008218; KEGG: dge:Dgeo_2048 vacuolar H+-transporting two-sector ATPase, F subunit; PFAM: ATPase, V1/A1 complex, subunit F; SPTR: V-type H+-ATPase subunit F; IMG reference gene:2504121594; PFAM: ATP synthase (F/14-kDa) subunit YP_004255022.1 COGs: COG1155 H+-ATPase subunit A; HAMAP: V-type ATP synthase catalytic subunit A/alpha; InterPro IPR022878:IPR004100:IPR000194:IPR000793; KEGG: dge:Dgeo_2047 V-type ATP synthase subunit A; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SPTR: V-type ATP synthase alpha chain; IMG reference gene:2504121595; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain YP_004255023.1 COGs: COG1156 H+-ATPase subunit B; HAMAP: V-type ATP synthase regulatory subunit B/beta; InterPro IPR022879:IPR004100:IPR000194:IPR000793; KEGG: ddr:Deide_01000 V-type ATP synthase subunit B; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SPTR: V-type ATP synthase beta chain; IMG reference gene:2504121596; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain YP_004255024.1 COGs: COG1394 H+-ATPase subunit D; HAMAP: ATPase, V1/A1 complex, subunit D; InterPro IPR002699; KEGG: dge:Dgeo_2045 V-type ATPase, D subunit; PFAM: ATPase, V1/A1 complex, subunit D; SPTR: V-type ATP synthase subunit D; TIGRFAM: ATPase, V1/A1 complex, subunit D; IMG reference gene:2504121597; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D YP_004255025.1 KEGG: dge:Dgeo_1585 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121598 YP_004255026.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: dge:Dgeo_1584 TrkA-N; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: K+ transport system, NAD-binding component; IMG reference gene:2504121599; PFAM: TrkA-N domain; TrkA-C domain YP_004255027.1 COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: nda:Ndas_5338 beta-lactamase; PFAM: Beta-lactamase-related; SPTR: Beta-lactamase; IMG reference gene:2504121600; PFAM: Beta-lactamase YP_004255028.1 KEGG: dra:DR_2550 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121601 YP_004255029.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445:IPR004772; KEGG: dra:DR_1667 potassium uptake protein KtrB; PFAM: Cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: Potassium uptake protein KtrB; TIGRFAM: Potassium uptake protein TrkH; IMG reference gene:2504121602; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_004255030.1 COGs: COG1279 Lysine efflux permease; InterPro IPR001123; KEGG: pmy:Pmen_1114 lysine exporter protein LysE/YggA; PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: Lysine exporter protein; IMG reference gene:2504121603; PFAM: LysE type translocator YP_004255031.1 COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520:IPR006055:IPR006054; KEGG: dge:Dgeo_1818 DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; IMG reference gene:2504121604; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family YP_004255032.1 InterPro IPR011717; KEGG: dge:Dgeo_2183 tetratricopeptide TPR_2; SPTR: TPR repeat protein; IMG reference gene:2504121605 YP_004255033.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: dra:DR_2351 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria; IMG reference gene:2504121606; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family YP_004255034.1 COGs: COG0282 Acetate kinase; HAMAP: Acetate kinase; InterPro IPR004372:IPR000890; KEGG: dge:Dgeo_0052 acetate kinase; PFAM: Acetate/butyrate kinase; PRIAM: Acetate kinase; SPTR: Acetate kinase; TIGRFAM: Acetate kinase; IMG reference gene:2504121607; PFAM: Acetokinase family; TIGRFAM: acetate kinase YP_004255035.1 COGs: COG0280 Phosphotransacetylase; InterPro IPR010766:IPR002505:IPR004614; KEGG: dge:Dgeo_0051 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; DRTGG; PRIAM: Phosphate acetyltransferase; SPTR: Phosphate acetyltransferase; TIGRFAM: Phosphate acetyltransferase; IMG reference gene:2504121608; PFAM: DRTGG domain; Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase YP_004255036.1 COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: dge:Dgeo_0267 hypothetical protein; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047; IMG reference gene:2504121609; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme YP_004255037.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: dra:DR_A0063 hypothetical protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121610; PFAM: GlcNAc-PI de-N-acetylase YP_004255038.1 InterPro IPR000182; KEGG: msv:Mesil_0813 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504121611; PFAM: Acetyltransferase (GNAT) family YP_004255039.1 COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: dra:DR_1645 UDP-N-acetyl-D-mannosaminuronic acid transferase, putative; PFAM: Glycosyl transferase WecB/TagA/CpsF; SPTR: UDP-N-acetyl-D-mannosaminuronic acid transferase, putative; TIGRFAM: Glycosyl transferase WecB/TagA/CpsF; IMG reference gene:2504121612; PFAM: Glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family YP_004255040.1 KEGG: nfa:nfa34180 putative translocator; SPTR: Putative translocator; IMG reference gene:2504121613 YP_004255041.1 COGs: COG0565 rRNA methylase; InterPro IPR001537:IPR004384; KEGG: dra:DR_0576 RNA methyltransferase, putative; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA methyltransferase, putative; TIGRFAM: RNA methyltransferase TrmH, group 1; IMG reference gene:2504121614; PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1 YP_004255042.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018:IPR011712:IPR003594; KEGG: dge:Dgeo_1992 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; GAF; SMART: ATPase-like, ATP-binding domain; GAF; SPTR: Multi-sensor signal transduction histidine kinase; IMG reference gene:2504121615; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain YP_004255043.1 KEGG: mbr:MONBRDRAFT_27324 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2504121616 YP_004255044.1 KEGG: dge:Dgeo_0289 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121617 YP_004255045.1 KEGG: dra:DR_2007 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121618; PFAM: Protein of unknown function (DUF3248) YP_004255046.1 COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: dge:Dgeo_1347 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504121619; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase YP_004255047.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: dra:DR_1430 metallo-beta-lactamase-related protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Metallo-beta-lactamase-related protein; IMG reference gene:2504121620; PFAM: Metallo-beta-lactamase superfamily YP_004255048.1 KEGG: ddr:Deide_11030 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504121621 YP_004255049.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125:IPR006262; KEGG: ddr:Deide_11961 putative cytidine deaminase (cytidine aminohydrolase); PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: Putative cytidine deaminase (Cytidine aminohydrolase); TIGRFAM: Cytidine deaminase, homotetrameric; IMG reference gene:2504121622; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_004255050.1 KEGG: ddr:Deide_03861 putative competence protein ComEA; SPTR: Putative Competence protein ComEA; IMG reference gene:2504121623 YP_004255051.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR001279:IPR004797; KEGG: ddr:Deide_03860 putative competence protein ComEC/Rec2; putative membrane protein; PFAM: ComEC/Rec2-related protein; Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Putative competence protein ComEC/Rec2; putative membrane protein; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; IMG reference gene:2504121624; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2 YP_004255052.1 COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: cst:CLOST_0432 glutaminyl-peptide cyclotransferase; PFAM: Peptidase M28; SPTR: Peptidase M28; IMG reference gene:2504121625; PFAM: Peptidase family M28 YP_004255053.1 COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265:IPR003651:IPR005760; KEGG: dge:Dgeo_0019 A/G-specific adenine glycosylase; PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SMART: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SPTR: A/G-specific adenine glycosylase; TIGRFAM: A/G-specific adenine glycosylase MutY, bacterial form; IMG reference gene:2504121626; PFAM: HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: A/G-specific adenine glycosylase YP_004255054.1 KEGG: dgr:Dgri_GH10507 GH10507 gene product from transcript GH10507-RA; SPTR: Putative uncharacterized protein; IMG reference gene:2504121627 YP_004255055.1 KEGG: dra:DR_0780 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121628 YP_004255056.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR003111:IPR003959:IPR008269:IPR003593:IPR 004815; KEGG: dra:DR_0349 ATP-dependent protease La; PFAM: Peptidase S16, Lon C-terminal; ATPase, AAA-type, core; Peptidase S16, lon N-terminal; PRIAM: Endopeptidase La; SMART: Peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: Lon protease; TIGRFAM: Peptidase S16, ATP-dependent protease La; IMG reference gene:2504121629; PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004255057.1 COGs: COG1678 Putative transcriptional regulator protein; InterPro IPR003774; KEGG: dge:Dgeo_0426 hypothetical protein; PFAM: Protein of unknown function DUF179; SPTR: Putative uncharacterized protein; IMG reference gene:2504121630; PFAM: Uncharacterized ACR, COG1678 YP_004255058.1 KEGG: tra:Trad_0193 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121631 YP_004255059.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: dge:Dgeo_1426 hypothetical protein; PFAM: Alanine racemase, N-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: pyridoxal phosphate-dependent enzyme, YBL036C type; IMG reference gene:2504121632; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_004255060.1 KEGG: bph:Bphy_1200 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121633 YP_004255061.1 KEGG: dra:DR_2073 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121634 YP_004255062.1 KEGG: dra:DR_1454 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121635 YP_004255063.1 KEGG: dge:Dgeo_2187 GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504121637; PFAM: Acetyltransferase (GNAT) family YP_004255064.1 KEGG: dge:Dgeo_2186 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121638 YP_004255065.1 KEGG: rer:RER_47350 hypothetical protein; SPTR: Conserved hypothetical membrane protein; IMG reference gene:2504121639 YP_004255066.1 COGs: COG2312 Erythromycin esterase homolog; InterPro IPR007815; KEGG: dra:DR_2257 erythromycin esterase, putative; PFAM: Erythromycin esterase; SPTR: Erythromycin esterase, putative; IMG reference gene:2504121640; PFAM: Erythromycin esterase YP_004255067.1 KEGG: mcl:MCCL_1908 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121641 YP_004255068.1 COGs: COG1476 transcriptional regulator protein; InterPro IPR001387; KEGG: dra:DR_2454 PbsX family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, PbsX family; IMG reference gene:2504121642; PFAM: Helix-turn-helix YP_004255069.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058:IPR020059:IPR018027:IPR004514; KEGG: dge:Dgeo_2188 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; Asn/Gln amidotransferase; PRIAM: Glutamine--tRNA ligase; SMART: Asn/Gln amidotransferase; SPTR: Glutaminyl-tRNA synthetase containing GatB/Yqey domain; TIGRFAM: Glutaminyl-tRNA synthetase, class Ic; IMG reference gene:2504121643; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; GatB domain; TIGRFAM: glutaminyl-tRNA synthetase YP_004255070.1 IMG reference gene:2504121644 YP_004255071.1 COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461:IPR004770; KEGG: rsk:RSKD131_1451 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter, NhaC family protein; TIGRFAM: Na+/H+ antiporter NhaC; IMG reference gene:2504121645; PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC YP_004255072.1 COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR001482:IPR003593:IPR006321; KEGG: dra:DR_0442 twitching motility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504121646; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT YP_004255073.1 COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: dra:DR_0886 hypothetical protein; PFAM: Na+/H+ antiporter subunit; SPTR: Putative uncharacterized protein; TIGRFAM: Na+/H+ antiporter subunit; IMG reference gene:2504121647; PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit YP_004255074.1 InterPro IPR007208; KEGG: dra:DR_0885 cation transport system protein, putative; PFAM: Multiple resistance and pH regulation protein F; SPTR: Cation transport system protein, putative; IMG reference gene:2504121648; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF) YP_004255075.1 COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: dra:DR_0884 putative monovalent cation/H+ antiporter subunit E; PFAM: cation antiporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504121649; PFAM: Na+/H+ ion antiporter subunit YP_004255076.1 COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: hel:HELO_3510 NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); IMG reference gene:2504121650; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains YP_004255077.1 COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: dra:DR_0882 cation transport system protein, putative; PFAM: NADH-ubiquinone oxidoreductase chain 4L/K; SPTR: Cation transport system protein, putative; IMG reference gene:2504121651; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; TIGRFAM: Multicomponent Na+:H+ antiporter, MnhC subunit YP_004255078.1 COGs: COG2111 Multisubunit Na+/H+ antiporter MnhB subunit; InterPro IPR007182; KEGG: dra:DR_0881 cation transport system protein, putative; PFAM: Na+/H+ antiporter MnhB subunit-related protein; SPTR: Cation transport system protein, putative; IMG reference gene:2504121652; PFAM: Domain related to MnhB subunit of Na+/H+ antiporter YP_004255079.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001516:IPR001750; KEGG: dra:DR_0880 NADH-ubiquinone/plastoquinone subunit, putative; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-ubiquinone/plastoquinone subunit, putative; IMG reference gene:2504121653; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus YP_004255080.1 COGs: COG4294 UV damage repair endonuclease; InterPro IPR004601; KEGG: dra:DR_1819 putative UV damage endonuclease; PFAM: UV-endonuclease UvdE; SPTR: UV DNA damage endonuclease; IMG reference gene:2504121654; PFAM: UV-endonuclease UvdE YP_004255081.1 COGs: COG4889 helicase; KEGG: mar:MAE_29040 adenine specific DNA methyltransferase; SPTR: Adenine specific DNA methyltransferase; IMG reference gene:2504121655; PFAM: N-6 DNA Methylase YP_004255082.1 KEGG: dra:DR_1458 hypothetical protein; SPTR: Probable RNA 2'-phosphotransferase; IMG reference gene:2504121656 YP_004255083.1 COGs: COG3335 Transposase and inactivated derivatives; KEGG: dra:DR_2425 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121657 YP_004255084.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: dge:Dgeo_0497 hypothetical protein; PFAM: Aminotransferase, class IV; SPTR: Branched-chain amino acid aminotransferase related enzyme; IMG reference gene:2504121658; PFAM: Aminotransferase class IV YP_004255085.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890:IPR000991:IPR006221; KEGG: dra:DR_0196 anthranilate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component I; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; IMG reference gene:2504121659; PFAM: Glutamine amidotransferase class-I; chorismate binding enzyme; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004255086.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dge:Dgeo_0499 BadM/Rrf2 family transcriptional regulator; PFAM: Transcription regulator Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcription regulator Rrf2; IMG reference gene:2504121660; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004255087.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: dge:Dgeo_1797 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; SPTR: Enoyl-CoA hydratase/isomerase; IMG reference gene:2504121661; PFAM: Enoyl-CoA hydratase/isomerase family YP_004255088.1 COGs: COG0816 endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); HAMAP: Resolvase, holliday junction-type, YqgF-like; InterPro IPR005227:IPR006641; KEGG: dra:DR_2509 hypothetical protein; PFAM: Resolvase, holliday junction-type, YqgF-like; SMART: Resolvase, RNase H-like fold; SPTR: Putative Holliday junction resolvase; TIGRFAM: Resolvase, holliday junction-type, YqgF-like; IMG reference gene:2504121662; PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: RNAse H-fold protein YqgF YP_004255089.1 COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: dge:Dgeo_0424 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; IMG reference gene:2504121663; PFAM: AMP-binding enzyme YP_004255090.1 COGs: COG2382 Enterochelin esterase; InterPro IPR000801; KEGG: dge:Dgeo_0423 putative esterase; PFAM: Putative esterase; SPTR: Ferric enterobactin esterase-related protein, alpha-beta hydrolase superfamily; IMG reference gene:2504121664; PFAM: Putative esterase YP_004255091.1 KEGG: dge:Dgeo_0422 hypothetical protein; SPTR: Peptidase C39 related protein; IMG reference gene:2504121665 YP_004255092.1 KEGG: dra:DR_0449 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121666; PFAM: RNase H YP_004255093.1 COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR000836:IPR006273; KEGG: dge:Dgeo_0138 orotate phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: Orotate phosphoribosyltransferase, Thermus type; IMG reference gene:2504121667; PFAM: Phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase, Thermus family YP_004255094.1 COGs: COG0054 Riboflavin synthase beta-chain; HAMAP: 6,7-dimethyl-8-ribityllumazine synthase; InterPro IPR002180; KEGG: ddr:Deide_02240 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; IMG reference gene:2504121668; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_004255095.1 COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR007848:IPR004556:IPR019874; KEGG: ddr:Deide_01670 putative protein HemK (M.VchAHemK2P); PFAM: Methyltransferase small; SPTR: Putative uncharacterized protein; TIGRFAM: Protein-(glutamine-N5) methyltransferase, release factor-specific; Modification methylase HemK; manually curated; IMG reference gene:2504121669; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; protein-(glutamine-N5) methyltransferase, release factor-specific YP_004255096.1 COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: ddr:Deide_01680 putative Jag-related protein, RNA binding protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: Putative Jag-related protein, RNA binding protein; IMG reference gene:2504121670; PFAM: R3H domain YP_004255097.1 COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198; KEGG: ddr:Deide_01400 putative short-chain dehydrogenase/reductase SDR precursor; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Putative Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504121671; PFAM: short chain dehydrogenase YP_004255098.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: Ribosomal protein S12 methylthiotransferase RimO; InterProIPR013848:IPR007197:IPR006638:IPR005839:IPR 005840; KEGG: dra:DR_A0189 ribosomal protein S12 methylthiotransferase; PFAM: Methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Ribosomal protein S12 methylthiotransferase rimO; TIGRFAM: Ribosomal protein S12 methylthiotransferase RimO; Methylthiotransferase; IMG reference gene:2504121672; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: ribosomal protein S12 methylthiotransferase RimO; radical SAM methylthiotransferase, MiaB/RimO family YP_004255099.1 COGs: COG0413 Ketopantoate hydroxymethyltransferase; HAMAP: Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: dra:DR_2615 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: Ketopantoate hydroxymethyltransferase; IMG reference gene:2504121673; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_004255100.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834:IPR006402; KEGG: dge:Dgeo_0096 HAD family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504121674; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004255101.1 KEGG: ddr:Deide_17770 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121675 YP_004255102.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: dge:Dgeo_1275 Crp/FNR family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp; Cyclic nucleotide-binding domain; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2504121676; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_004255103.1 COGs: COG4365 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0747; InterPro IPR011199; KEGG: dge:Dgeo_1276 hypothetical protein; PFAM: Uncharacterised protein family UPF0747; SPTR: UPF0747 protein Dgeo_1276; IMG reference gene:2504121677; PFAM: Uncharacterized protein conserved in bacteria (DUF2317); TIGRFAM: bacillithiol biosynthesis cysteine-adding enzyme BshC YP_004255104.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: dra:DR_0180 RNA polymerase sigma-E factor; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; SPTR: RNA polymerase sigma-E factor; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504121678; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004255105.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843; KEGG: dra:DR_1884 transcriptional regulator; PFAM: HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator; IMG reference gene:2504121679; PFAM: Bacterial regulatory proteins, lacI family YP_004255106.1 COGs: COG1054 sulfurtransferase; HAMAP: Uncharacterised protein family UPF0176; InterPro IPR001763:IPR020936; KEGG: ddr:Deide_16150 putative rhodanese homology domain protein; putative sulfurtransferase; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: UPF0176 protein Deide_16150; IMG reference gene:2504121680; PFAM: Rhodanese-like domain YP_004255107.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: dge:Dgeo_0506 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ATPase component of ABC transporter, containing duplicated ATPase domains; IMG reference gene:2504121681; PFAM: ABC transporter YP_004255108.1 KEGG: dge:Dgeo_0507 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121682 YP_004255109.1 InterPro IPR002559; KEGG: dra:DR_C0033 transposase, putative; PFAM: Transposase, IS4-like; SPTR: Transposase, putative; IMG reference gene:2504121684; PFAM: Transposase DDE domain YP_004255110.1 KEGG: dre:560594 similar to GTPase activating Rap/RanGAP domain-like 3; SPTR: Novel protein similar to human and mouse GTPase activating Rap/RanGAP domain-like 3 (GARNL3); IMG reference gene:2504121685 YP_004255111.1 KEGG: cre:CHLREDRAFT_178094 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121686 YP_004255112.1 COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: hna:Hneap_0477 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504121687; PFAM: Sodium/hydrogen exchanger family YP_004255113.1 InterPro IPR004942; KEGG: dge:Dgeo_1816 roadblock/LC7 domain-contain protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related; SPTR: Roadblock/LC7; IMG reference gene:2504121688; PFAM: Roadblock/LC7 domain YP_004255114.1 COGs: COG2229 GTPase; KEGG: dge:Dgeo_1815 gliding motility protein; SPTR: GTPase Rab/Ras family; IMG reference gene:2504121689; PFAM: ADP-ribosylation factor family YP_004255115.1 COGs: COG2032 Cu/Zn superoxide dismutase; InterPro IPR001424; KEGG: dra:DR_A0202 Cu/Zn family superoxide dismutase; PFAM: Superoxide dismutase, copper/zinc binding; SPTR: Superoxide dismutase [Cu-Zn]; IMG reference gene:2504121690; PFAM: Copper/zinc superoxide dismutase (SODC) YP_004255116.1 COGs: COG2032 Cu/Zn superoxide dismutase; InterPro IPR001424:IPR013658; KEGG: dra:DR_A0202 Cu/Zn family superoxide dismutase; PFAM: Superoxide dismutase, copper/zinc binding; SMP-30/Gluconolaconase/LRE-like region; SPTR: Superoxide dismutase [Cu-Zn]; IMG reference gene:2504121691; PFAM: SMP-30/Gluconolaconase/LRE-like region; Copper/zinc superoxide dismutase (SODC) YP_004255117.1 COGs: COG2133 Glucose/sorbosone dehydrogenase; InterPro IPR012938; KEGG: ddr:Deide_1p00750 putative glucose/sorbosone dehydrogenase, precursor; SPTR: Putative glucose/sorbosone dehydrogenase,; IMG reference gene:2504121692; PFAM: Glucose / Sorbosone dehydrogenase; Membrane bound L-sorbosone dehydrogenase YP_004255118.1 COGs: COG2107 periplasmic solute-binding protein; KEGG: dge:Dgeo_1810 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121693; PFAM: Putative periplasminc binding protein (DUF178) YP_004255119.1 COGs: COG2340 Uncharacterized protein with SCP/PR1 domains; InterPro IPR014044; KEGG: dra:DR_1009 hypothetical protein; PFAM: CAP domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121696; PFAM: Cysteine-rich secretory protein family YP_004255120.1 COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: pfo:Pfl01_2034 VanW; PFAM: Vancomycin resistance VanW; SPTR: Putative uncharacterized protein; IMG reference gene:2504121697; PFAM: VanW like protein YP_004255121.1 COGs: COG0196 FAD synthase; InterPro IPR015864:IPR015865:IPR002606; KEGG: dra:DR_1008 riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin kinase/FMN adenylyltransferase; TIGRFAM: Riboflavin kinase/FAD synthetase; IMG reference gene:2504121698; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase YP_004255122.1 InterPro IPR000086; KEGG: ddr:Deide_17700 putative NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: Putative NUDIX hydrolase; IMG reference gene:2504121699; PFAM: NUDIX domain YP_004255123.1 COGs: COG0232 dGTP triphosphohydrolase; HAMAP: Deoxyguanosinetriphosphate triphosphohydrolase, type 2; InterPro IPR006674:IPR003607:IPR006261:IPR023023; KEGG: dge:Dgeo_1804 deoxyguanosinetriphosphate triphosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Deoxyguanosinetriphosphate triphosphohydrolase-like protein; TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2504121700; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative YP_004255124.1 KEGG: sbi:SORBI_01g008580 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121701 YP_004255125.1 InterPro IPR005821; KEGG: dra:DR_0830 ion transporter, putative; PFAM: Ion transport; SPTR: Ion transporter, putative; IMG reference gene:2504121702; PFAM: Ion transport protein YP_004255126.1 KEGG: sma:SAV_3402 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121703 YP_004255127.1 KEGG: sna:Snas_1934 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121704 YP_004255128.1 KEGG: tcr:506227.170 hypothetical protein; IMG reference gene:2504121705 YP_004255129.1 KEGG: ddr:Deide_20910 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504121706 YP_004255130.1 InterPro IPR002559; KEGG: dge:Dgeo_1090 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4; manually curated; IMG reference gene:2504121707 YP_004255131.1 KEGG: dra:DR_1671 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121708 YP_004255132.1 KEGG: dge:Dgeo_1560 S-layer-like protein array-related protein; SPTR: S-layer-like protein array-related protein; IMG reference gene:2504121709 YP_004255133.1 COGs: COG2340 Uncharacterized protein with SCP/PR1 domains; InterPro IPR000601:IPR014044:IPR022409; KEGG: dge:Dgeo_1557 allergen V5/TPX-1 related; PFAM: CAP domain; PKD domain; SMART: PKD/Chitinase domain; SPTR: Uncharacterized protein containing SCP/PR1 domain; IMG reference gene:2504121710; PFAM: Cysteine-rich secretory protein family; PKD domain YP_004255134.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: ddr:Deide_21630 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121711; PFAM: SNARE associated Golgi protein YP_004255135.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: dge:Dgeo_2761 acyl-CoA dehydrogenase-like; PFAM: Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA oxidase/dehydrogenase, type 1; PRIAM: Glutaryl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase-like protein; IMG reference gene:2504121712; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004255136.1 COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633:IPR019734; KEGG: ddr:Deide_16860 putative C-di-GMP phosphodiesterase A; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative c-di-GMP phosphodiesterase A; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504121713; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004255137.1 COGs: COG0239 Integral membrane protein possibly involved in chromosome condensation; HAMAP: Camphor resistance CrcB protein; InterPro IPR003691; KEGG: dge:Dgeo_0149 CrcB protein; PFAM: Camphor resistance CrcB protein; SPTR: Protein CrcB homolog 1; TIGRFAM: Camphor resistance CrcB protein; IMG reference gene:2504121714; PFAM: CrcB-like protein; TIGRFAM: crcB protein YP_004255138.1 KEGG: ddr:Deide_12771 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504121715 YP_004255139.1 COGs: COG1570 Exonuclease VII large subunit; InterPro IPR020579; KEGG: ddr:Deide_22980 exodeoxyribonuclease VII large subunit; PFAM: Exonuclease VII, large subunit, C-terminal; PRIAM: Exodeoxyribonuclease VII; SPTR: Putative Exodeoxyribonuclease VII large subunit; IMG reference gene:2504121716; PFAM: Exonuclease VII, large subunit YP_004255140.1 InterPro IPR000182; KEGG: ddr:Deide_04110 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121717; PFAM: Acetyltransferase (GNAT) family YP_004255141.1 InterPro IPR000182; KEGG: hau:Haur_0953 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504121718; PFAM: Acetyltransferase (GNAT) family YP_004255142.1 COGs: COG0287 Prephenate dehydrogenase; InterPro IPR020822:IPR003099:IPR002701:IPR011277; KEGG: sea:SeAg_B2813 bifunctional chorismate mutase/prephenate dehydrogenase; PFAM: Chorismate mutase, type II; Prephenate dehydrogenase; PRIAM: Chorismate mutase; SMART: Chorismate mutase; SPTR: T-protein; TIGRFAM: Chorismate mutase, T-protein; IMG reference gene:2504121719; PFAM: Prephenate dehydrogenase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of T-protein YP_004255143.1 COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR002701:IPR 010957; KEGG: kse:Ksed_23140 chorismate mutase, clade 2; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; SMART: Chorismate mutase; SPTR: Chorismate mutase, clade 2; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; IMG reference gene:2504121720; PFAM: Prephenate dehydratase; Chorismate mutase type II; ACT domain; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2 YP_004255144.1 COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; KEGG: kse:Ksed_00590 Mn2+/Fe2_ transporter, NRAMP family; SPTR: Mn2+/Fe2_transporter, NRAMP family; manually curated; IMG reference gene:2504121721 YP_004255145.1 COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: dge:Dgeo_0159 3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese-like; PRIAM: 3-mercaptopyruvate sulfurtransferase; SMART: Rhodanese-like; SPTR: 3-mercaptopyruvate sulfurtransferase; IMG reference gene:2504121722; PFAM: Rhodanese-like domain YP_004255146.1 KEGG: dra:DR_1746 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121723 YP_004255147.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915; KEGG: ddr:Deide_13240 putative membrane-associated zinc metalloproteases; putative membrane protein; PFAM: Peptidase M50; SPTR: Putative membrane-associated zinc metalloproteases; putative membrane protein; IMG reference gene:2504121724; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP YP_004255148.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; HAMAP: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR013512:IPR013644:IPR003821; KEGG: ddr:Deide_13230 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal; 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; IMG reference gene:2504121725; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004255149.1 InterPro IPR007530; KEGG: ppm:PPSC2_c2388 aminoglycoside 6-adenylyltransferase, putative; PFAM: Streptomycin adenylyltransferase; SPTR: Putative aminoglycoside 6-adenylyltransferase; IMG reference gene:2504121726; PFAM: Streptomycin adenylyltransferase YP_004255150.1 COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR000581:IPR004404; KEGG: ddr:Deide_10590 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; IMG reference gene:2504121727; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase YP_004255151.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001:IPR012000:IPR011766:IPR012846; KEGG: dra:DR_1516 acetolactate synthase, large subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; IMG reference gene:2504121728; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type YP_004255152.1 COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: dge:Dgeo_0601 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; IMG reference gene:2504121729; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit YP_004255153.1 COGs: COG0059 Ketol-acid reductoisomerase; HAMAP: Acetohydroxy acid isomeroreductase; InterPro IPR013116:IPR000506:IPR013023; KEGG: ddr:Deide_16830 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase, catalytic; Acetohydroxy acid isomeroreductase C-terminal; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: Acetohydroxy acid isomeroreductase; IMG reference gene:2504121730; PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase YP_004255154.1 COGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR001721:IPR005787; KEGG: ddr:Deide_04330 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Threonine dehydratase, C-terminal; SPTR: Putative Threonine dehydratase biosynthetic,(Threonine deaminase); TIGRFAM: Threonine dehydratase I; IMG reference gene:2504121731; PFAM: C-terminal regulatory domain of Threonine dehydratase; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form YP_004255155.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: ddr:Deide_13220 putative phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; IMG reference gene:2504121732; PFAM: Cytidylyltransferase family YP_004255156.1 COGs: COG0233 Ribosome recycling factor; HAMAP: Ribosome recycling factor, bacterial-like; InterPro IPR002661:IPR015998; KEGG: dge:Dgeo_1046 ribosome recycling factor; PFAM: Ribosome recycling factor; SPTR: Ribosome-recycling factor; TIGRFAM: Ribosome recycling factor; IMG reference gene:2504121733; PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_004255157.1 COGs: COG0528 Uridylate kinase; InterPro IPR001048:IPR015963; KEGG: dra:DR_1511 uridylate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Uridylate kinase; TIGRFAM: Uridylate kinase, bacteria; IMG reference gene:2504121734; PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase YP_004255158.1 COGs: COG0264 Translation elongation factor Ts; HAMAP: Translation elongation factor EFTs/EF1B; InterPro IPR000449:IPR014039:IPR001816; KEGG: dge:Dgeo_1048 elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B, dimerisation; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; SPTR: Elongation factor Ts; TIGRFAM: Translation elongation factor EFTs/EF1B; IMG reference gene:2504121735; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts YP_004255159.1 COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR005706; KEGG: dge:Dgeo_1049 30S ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; IMG reference gene:2504121736; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_004255160.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398; KEGG: dge:Dgeo_0285 hypothetical protein; PFAM: RNA methyltransferase, RsmD; SPTR: SAM-dependent methyltransferase, rRNA adenine N-6-methyltransferase family; IMG reference gene:2504121737; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family YP_004255161.1 COGs: COG0669 Phosphopantetheine adenylyltransferase; HAMAP: Coenzyme A biosynthesis protein; InterPro IPR004820:IPR004821:IPR001980; KEGG: dge:Dgeo_0286 phosphopantetheine adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Phosphopantetheine adenylyltransferase; TIGRFAM: Coenzyme A biosynthesis protein; Cytidyltransferase-related; IMG reference gene:2504121738; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_004255162.1 COGs: COG2340 Uncharacterized protein with SCP/PR1 domains; InterPro IPR014044; KEGG: dra:DR_1009 hypothetical protein; PFAM: CAP domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121739; PFAM: Cysteine-rich secretory protein family YP_004255163.1 COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterPro IPR003661:IPR003594; KEGG: gsu:GSU0103 sensory box histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Sensory box histidine kinase; IMG reference gene:2504121740; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004255164.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: ddr:Deide_3p02360 putative response regulator, CheY; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Putative response regulator, CheY; IMG reference gene:2504121741; PFAM: Response regulator receiver domain YP_004255165.1 COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: ddr:Deide_01420 putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related; SPTR: Putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; IMG reference gene:2504121742; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases YP_004255166.1 KEGG: dra:DR_0338 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121743 YP_004255167.1 COGs: COG0360 Ribosomal protein S6; HAMAP: Ribosomal protein S6, plastid/chloroplast; InterPro IPR000529:IPR020814; KEGG: dra:DR_0098 30S ribosomal protein S6; PFAM: Ribosomal protein S6; SPTR: 30S ribosomal protein S6; TIGRFAM: Ribosomal protein S6; IMG reference gene:2504121744; PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_004255168.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: dge:Dgeo_0165 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504121745; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004255169.1 COGs: COG0238 Ribosomal protein S18; HAMAP: Ribosomal protein S18; InterPro IPR001648; KEGG: ddr:Deide_00110 30S ribosomal protein S18; PFAM: Ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: Ribosomal protein S18; IMG reference gene:2504121746; PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_004255170.1 COGs: COG0359 Ribosomal protein L9; HAMAP: Ribosomal protein L9, bacteria/chloroplast; InterPro IPR020070:IPR020069:IPR020594; KEGG: ddr:Deide_00100 50S ribosomal protein L9; PFAM: Ribosomal protein L9, C-terminal; Ribosomal protein L9, N-terminal; SPTR: 50S ribosomal protein L9; TIGRFAM: Ribosomal protein L9, bacteria/chloroplast; IMG reference gene:2504121747; PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_004255171.1 KEGG: dge:Dgeo_1437 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121748 YP_004255172.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: dra:DR_B0128 hemolysin, putative; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: Hemolysin, putative; IMG reference gene:2504121749; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004255173.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: dra:DR_B0129 hemolysin, putative; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: Hemolysin, putative; IMG reference gene:2504121750; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004255174.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445:IPR004772; KEGG: dra:DR_1668 potassium uptake protein KtrB; PFAM: Cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: Potassium uptake protein KtrB; TIGRFAM: Potassium uptake protein TrkH; IMG reference gene:2504121751; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_004255175.1 COGs: COG2352 Phosphoenolpyruvate carboxylase; HAMAP: Phosphoenolpyruvate carboxylase, bacterial/plant-type; InterPro IPR021135:IPR022805; KEGG: dra:DR_1283 phosphoenolpyruvate carboxylase; PFAM: Phosphoenolpyruvate carboxylase; PRIAM: Phosphoenolpyruvate carboxylase; SPTR: Phosphoenolpyruvate carboxylase; IMG reference gene:2504121752; PFAM: Phosphoenolpyruvate carboxylase YP_004255176.1 KEGG: dra:DR_1979 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121753 YP_004255177.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959:IPR003593; KEGG: ddr:Deide_04980 recombination factor protein RarA; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Putative DNA-dependent ATPase; IMG reference gene:2504121754; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA) YP_004255178.1 KEGG: dra:DR_1896 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121755 YP_004255179.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795:IPR004161:IPR004160:IPR004541:IPR 005225; KEGG: ddr:Deide_18970 elongation factor Tu; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; SPTR: Elongation factor Tu; TIGRFAM: Translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; IMG reference gene:2504121756; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004255180.1 COGs: COG0051 Ribosomal protein S10; HAMAP: Ribosomal protein S10 subgroup; InterPro IPR001848:IPR005731; KEGG: ddr:Deide_18960 30S ribosomal protein S10; PFAM: Ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: Ribosomal protein S10 subgroup; IMG reference gene:2504121757; PFAM: Ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle YP_004255181.1 COGs: COG0087 Ribosomal protein L3; InterPro IPR000597:IPR019927; KEGG: dge:Dgeo_1867 50S ribosomal protein L3; PFAM: Ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: Ribosomal protein L3, bacterial/organelle-type; IMG reference gene:2504121758; PFAM: Ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial YP_004255182.1 COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: dge:Dgeo_1866 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; IMG reference gene:2504121759; PFAM: Ribosomal protein L4/L1 family; TIGRFAM: 50S ribosomal protein L4, bacterial/organelle YP_004255183.1 COGs: COG0089 Ribosomal protein L23; InterPro IPR013025; KEGG: dra:DR_0313 50S ribosomal protein L23; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; IMG reference gene:2504121760; PFAM: Ribosomal protein L23 YP_004255184.1 COGs: COG0090 Ribosomal protein L2; InterPro IPR022666:IPR022669:IPR005880; KEGG: dge:Dgeo_1864 50S ribosomal protein L2; PFAM: Ribosomal protein L2, C-terminal; Ribosomal Proteins L2, RNA binding domain; SPTR: 50S ribosomal protein L2; TIGRFAM: Ribosomal protein L2, bacterial-type; IMG reference gene:2504121761; PFAM: Ribosomal Proteins L2, RNA binding domain; Ribosomal Proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar YP_004255185.1 COGs: COG0185 Ribosomal protein S19; InterPro IPR002222:IPR005732; KEGG: ddr:Deide_18910 30S ribosomal protein S19; PFAM: Ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: Ribosomal protein S19, bacterial-type; IMG reference gene:2504121762; PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_004255186.1 COGs: COG0091 Ribosomal protein L22; InterPro IPR001063:IPR005727; KEGG: dra:DR_0316 50S ribosomal protein L22; PFAM: Ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: Ribosomal protein L22, bacterial-type; IMG reference gene:2504121763; PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_004255187.1 COGs: COG0092 Ribosomal protein S3; InterProIPR008282:IPR004044:IPR001351:IPR004087:IPR 005704; KEGG: dge:Dgeo_1861 30S ribosomal protein S3; PFAM: Ribosomal protein S3, C-terminal; Ribosomal protein S3, N-terminal; K Homology, type 2; SMART: K Homology; SPTR: 30S ribosomal protein S3; TIGRFAM: Ribosomal protein S3, bacterial; IMG reference gene:2504121764; PFAM: KH domain; Ribosomal protein S3, C-terminal domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type YP_004255188.1 COGs: COG0197 Ribosomal protein L16/L10E; HAMAP: Ribosomal protein L16; InterPro IPR016180:IPR000114; KEGG: ddr:Deide_18880 50S ribosomal protein L16; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: Ribosomal protein L16; IMG reference gene:2504121765; PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_004255189.1 InterPro IPR001854; KEGG: ddr:Deide_18870 50S ribosomal protein L29; PFAM: Ribosomal protein L29; SPTR: 50S ribosomal protein L29; TIGRFAM: Ribosomal protein L29; IMG reference gene:2504121766; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_004255190.1 COGs: COG0186 Ribosomal protein S17; InterPro IPR000266:IPR019984; KEGG: dra:DR_0320 30S ribosomal protein S17; PFAM: Ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: Ribosomal protein S17, bacterial-type; IMG reference gene:2504121767; PFAM: Ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17 YP_004255191.1 COGs: COG0093 Ribosomal protein L14; InterPro IPR000218:IPR005745; KEGG: dra:DR_0321 50S ribosomal protein L14; PFAM: Ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: Ribosomal protein L14, bacterial-type; IMG reference gene:2504121768; PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_004255192.1 COGs: COG0198 Ribosomal protein L24; InterPro IPR005824:IPR003256; KEGG: ddr:Deide_18840 50S ribosomal protein L24; PFAM: KOW; SMART: KOW; SPTR: 50S ribosomal protein L24; TIGRFAM: Ribosomal protein L24; IMG reference gene:2504121769; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle YP_004255193.1 COGs: COG0094 Ribosomal protein L5; InterPro IPR002132; KEGG: dra:DR_0323 50S ribosomal protein L5; PFAM: Ribosomal protein L5; SPTR: 50S ribosomal protein L5; IMG reference gene:2504121770; PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5 YP_004255194.1 COGs: COG0199 Ribosomal protein S14; HAMAP: Ribosomal protein S14, bacterial/plastid; InterPro IPR001209:IPR023036; KEGG: dra:DR_2109 ribosomal protein S14; PFAM: Ribosomal protein S14; SPTR: 30S ribosomal protein S14; IMG reference gene:2504121771; PFAM: Ribosomal protein S14p/S29e YP_004255195.1 COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: dge:Dgeo_1853 30S ribosomal protein S8; PFAM: Ribosomal protein S8; SPTR: 30S ribosomal protein S8; IMG reference gene:2504121772; PFAM: Ribosomal protein S8 YP_004255196.1 COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR020040:IPR019906; KEGG: dra:DR_2111 50S ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: Ribosomal protein L6, bacterial-type; IMG reference gene:2504121773; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type YP_004255197.1 COGs: COG0256 Ribosomal protein L18; InterPro IPR005484:IPR004389; KEGG: ddr:Deide_18790 50S ribosomal protein L18; PFAM: Ribosomal protein L18/L5; SPTR: 50S ribosomal protein L18; TIGRFAM: Ribosomal protein L18, bacterial; IMG reference gene:2504121774; PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_004255198.1 COGs: COG0098 Ribosomal protein S5; InterPro IPR013810:IPR005324:IPR005712; KEGG: dge:Dgeo_1850 30S ribosomal protein S5; PFAM: Ribosomal protein S5, N-terminal; Ribosomal protein S5, C-terminal; SPTR: 30S ribosomal protein S5; TIGRFAM: Ribosomal protein S5, bacterial-type; IMG reference gene:2504121775; PFAM: Ribosomal protein S5, N-terminal domain; Ribosomal protein S5, C-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_004255199.1 COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR016082:IPR005996; KEGG: ddr:Deide_18770 50S ribosomal protein L30; PFAM: Ribosomal protein L30, ferredoxin-like fold domain; SPTR: 50S ribosomal protein L30; TIGRFAM: Ribosomal protein L30, bacterial-type; IMG reference gene:2504121776; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_004255200.1 COGs: COG0200 Ribosomal protein L15; InterPro IPR005749; KEGG: ddr:Deide_18760 50S ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: Ribosomal protein L15, bacterial-type; IMG reference gene:2504121777; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_004255201.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208; KEGG: dra:DR_2116 preprotein translocase subunit SecY; PFAM: SecY protein; SPTR: Preprotein translocase subunit secY; TIGRFAM: SecY protein; IMG reference gene:2504121778; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit YP_004255202.1 COGs: COG0563 Adenylate kinase and related kinase; HAMAP: Adenylate kinase; InterPro IPR000850:IPR006259; KEGG: dge:Dgeo_1846 adenylate kinase; PFAM: Adenylate kinase; SPTR: Adenylate kinase; TIGRFAM: Adenylate kinase, subfamily; IMG reference gene:2504121779; PFAM: Adenylate kinase; TIGRFAM: adenylate kinases YP_004255203.1 COGs: COG0361 Translation initiation factor 1 (IF-1); HAMAP: Translation initiation factor IF-1; InterPro IPR006196:IPR004368; KEGG: dge:Dgeo_1845 translation initiation factor IF-1; PFAM: RNA-binding domain, S1, IF1 type; SPTR: Putative Translation initiation factor IF-1; TIGRFAM: Translation initiation factor IF-1; IMG reference gene:2504121780; PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_004255204.1 IMG reference gene:2504121781 YP_004255205.1 HAMAP: Ribosomal protein L36; InterPro IPR000473; KEGG: dge:Dgeo_1844 50S ribosomal protein L36; PFAM: Ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: Ribosomal protein L36; IMG reference gene:2504121782; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_004255206.1 COGs: COG0099 Ribosomal protein S13; InterPro IPR001892:IPR019980; KEGG: ddr:Deide_18660 30S ribosomal protein S13; PFAM: Ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: Ribosomal protein S13, bacterial-type; IMG reference gene:2504121783; PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13 YP_004255207.1 COGs: COG0100 Ribosomal protein S11; InterPro IPR001971:IPR019981; KEGG: ddr:Deide_18650 30S ribosomal protein S11; PFAM: Ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: Ribosomal protein S11, bacterial-type; IMG reference gene:2504121784; PFAM: Ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11 YP_004255208.1 COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR001912:IPR002942:IPR005709; KEGG: dge:Dgeo_1841 30S ribosomal protein S4; PFAM: RNA-binding S4; Ribosomal protein S4/S9, N-terminal; SMART: RNA-binding S4; SPTR: 30S ribosomal protein S4; TIGRFAM: Ribosomal protein S4, bacterial-type; IMG reference gene:2504121785; PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type YP_004255209.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; HAMAP: DNA-directed RNA polymerase, alpha subunit; InterPro IPR011261:IPR011262:IPR011263:IPR011773; KEGG: dge:Dgeo_1840 DNA-directed RNA polymerase subunit alpha; PFAM: DNA-directed RNA polymerase, insert domain; DNA-directed RNA polymerase, dimerisation; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; IMG reference gene:2504121786; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type YP_004255210.1 COGs: COG0203 Ribosomal protein L17; HAMAP: Ribosomal protein L17; InterPro IPR000456; KEGG: dge:Dgeo_1839 50S ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17; IMG reference gene:2504121787; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_004255211.1 COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: dra:DR_0944 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; IMG reference gene:2504121788; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004255212.1 InterPro IPR005500; KEGG: dge:Dgeo_1836 hypothetical protein; PFAM: Protein of unknown function DUF309; SPTR: Putative uncharacterized protein; IMG reference gene:2504121789; PFAM: Domain of unknown function (DUF309) YP_004255213.1 COGs: COG1432 conserved hypothetical protein; InterPro IPR021139; KEGG: ddr:Deide_18580 hypothetical protein; PFAM: Domain of unknown function DUF88; SPTR: Putative uncharacterized protein; IMG reference gene:2504121790; PFAM: Protein of unknown function DUF88 YP_004255214.1 COGs: COG0416 Fatty acid/phospholipid biosynthesis enzyme; HAMAP: Phospholipid biosynthesis protein, PlsX-like; InterPro IPR003664:IPR012281; KEGG: ddr:Deide_18570 putative glycerol-3-phosphate acyltransferase PlsX; PFAM: Fatty acid synthesis PlsX protein; SPTR: Phosphate acyltransferase; TIGRFAM: Phospholipid biosynthesis protein, PlsX-like; IMG reference gene:2504121791; PFAM: Fatty acid synthesis protein; TIGRFAM: fatty acid/phospholipid synthesis protein PlsX YP_004255215.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR011546:IPR003959:IPR000642:IPR003593:IPR 005936; KEGG: dra:DR_1020 cell division protein FtsH; PFAM: ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; Peptidase M41; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cell division protein FtsH; TIGRFAM: Peptidase M41, FtsH; IMG reference gene:2504121792; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004255216.1 KEGG: dge:Dgeo_1831 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121793 YP_004255217.1 InterPro IPR004518; KEGG: ddr:Deide_18530 putative pyrophosphatase; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: Putative pyrophosphatase; IMG reference gene:2504121794; PFAM: MazG nucleotide pyrophosphohydrolase domain YP_004255218.1 COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ddr:Deide_06142 putative peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Putative Peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ; IMG reference gene:2504121795; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ YP_004255219.1 COGs: COG0372 Citrate synthase; InterPro IPR002020:IPR011278; KEGG: ddr:Deide_06150 putative citrate (Si)-synthase (citrate synthase); PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Putative citrate (Si)-synthase (Citrate synthase); TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; IMG reference gene:2504121796; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II YP_004255220.1 KEGG: ddr:Deide_06160 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121797 YP_004255221.1 COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: dge:Dgeo_1529 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Calcineurin-like phosphoesterase; TIGRFAM: Phosphodiesterase MJ0936; IMG reference gene:2504121798; TIGRFAM: phosphoesterase, MJ0936 family YP_004255222.1 KEGG: ddr:Deide_06180 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121799 YP_004255223.1 COGs: COG1520 FOG: WD40-like repeat; InterPro IPR002372:IPR018391; KEGG: dra:DR_1769 serine/threonine protein kinase-related protein; PFAM: Pyrrolo-quinoline quinone repeat; SMART: Pyrrolo-quinoline quinone beta-propeller repeat; SPTR: Serine/threonine protein kinase-related protein; IMG reference gene:2504121800; PFAM: PQQ enzyme repeat YP_004255224.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR018113:IPR003352:IPR011296:IPR011535; KEGG: cbe:Cbei_2320 PTS system, trehalose-specific IIBC subunit; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Putative uncharacterized protein; TIGRFAM: Phosphotransferase system, trehalose-specific IIBC component; Phosphotransferase system, glucose-like IIB component; IMG reference gene:2504121802; PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB; TIGRFAM: PTS system, trehalose-specific IIBC component; PTS system, glucose-like IIB component YP_004255225.1 COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: csh:Closa_3360 alpha,alpha-phosphotrehalase; PFAM: Glycosyl hydrolase, family 13, catalytic domain; PRIAM: Alpha,alpha-phosphotrehalase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121803; PFAM: Alpha amylase, catalytic domain YP_004255226.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093:IPR000644:IPR005990; KEGG: dge:Dgeo_0548 inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; PRIAM: IMP dehydrogenase; SMART: Cystathionine beta-synthase, core; SPTR: Inosine-5'-monophosphate dehydrogenase; TIGRFAM: IMP dehydrogenase; IMG reference gene:2504121804; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_004255227.1 InterPro IPR008915; KEGG: dge:Dgeo_0550 peptidase M50; PFAM: Peptidase M50; SPTR: Peptidase M50; IMG reference gene:2504121805; PFAM: Peptidase family M50 YP_004255228.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646; KEGG: dge:Dgeo_0551 polynucleotide adenylyltransferase region; PFAM: Poly A polymerase, head domain; SPTR: tRNA nucleotidyltransferase, Cca; IMG reference gene:2504121806; PFAM: Poly A polymerase head domain YP_004255229.1 KEGG: cro:ROD_04491 hypothetical protein; SPTR: Putative exported protein; IMG reference gene:2504121807 YP_004255230.1 COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: ddr:Deide_10000 putative MaoC protein (monoamine oxidase); PFAM: MaoC-like dehydratase; SPTR: Putative MaoC protein (Monoamine oxidase); IMG reference gene:2504121808; PFAM: MaoC like domain YP_004255231.1 COGs: COG2301 Citrate lyase beta subunit; InterPro IPR005000; KEGG: dge:Dgeo_1253 citryl-CoA lyase; PFAM: Aldehyde-lyase domain; PRIAM: Citryl-CoA lyase; SPTR: Citryl-CoA lyase; IMG reference gene:2504121809; PFAM: HpcH/HpaI aldolase/citrate lyase family YP_004255232.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; HAMAP: Glutamyl-tRNA(Gln) amidotransferase A subunit; InterPro IPR000120:IPR004412; KEGG: ddr:Deide_08620 aspartyl/glutamyl-tRNA amidotransferase subunit A; PFAM: Amidase; SPTR: Glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase A subunit; IMG reference gene:2504121810; PFAM: Amidase; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit YP_004255233.1 COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: dge:Dgeo_0759 putative transcriptional regulator; PFAM: Chromosome segregation/condensation protein ScpB, prokaryote; SPTR: Putative transcriptional regulator; TIGRFAM: Chromosome segregation/condensation protein ScpB, prokaryote; IMG reference gene:2504121811; PFAM: Putative transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B YP_004255234.1 COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: dge:Dgeo_0758 SUA5/YciO/YrdC/YwlC; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Sua5/YciO/YrdC/YwlC; IMG reference gene:2504121812; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004255235.1 COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: dra:DR_1863 pilin biogenesis protein; PFAM: Type II secretion system F domain; SPTR: Pilin biogenesis protein; IMG reference gene:2504121813; PFAM: Bacterial type II secretion system protein F domain YP_004255236.1 COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045:IPR010822:IPR001932; KEGG: ddr:Deide_20090 putative phosphoprotein phosphatase; putative membrane protein; PFAM: Protein phosphatase 2C, N-terminal; Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-like; SPTR: Putative phosphoprotein phosphatase; putative membrane protein; manually curated; IMG reference gene:2504121814; PFAM: Protein phosphatase 2C YP_004255237.1 COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006175:IPR006056; KEGG: dge:Dgeo_0230 YjgF-like protein protein; PFAM: Endoribonuclease L-PSP; SPTR: YjgF-like protein protein; TIGRFAM: YjgF-like protein; IMG reference gene:2504121815; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative YP_004255238.1 KEGG: sye:Syncc9902_1753 putative cytochrome c oxidase assembly protein; SPTR: Putative cytochrome c oxidase assembly protein; IMG reference gene:2504121816 YP_004255239.1 COGs: COG0388 amidohydrolase; InterPro IPR003010:IPR017755; KEGG: dra:DR_2535 hydrolase, putative; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: N-carbamoylputrescine amidase; SPTR: Hydrolase, putative; TIGRFAM: N-carbamoylputrescine amidase; IMG reference gene:2504121817; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: N-carbamoylputrescine amidase YP_004255240.1 COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR014033; KEGG: dge:Dgeo_0292 arginase; PFAM: Ureohydrolase; PRIAM: Arginase; SPTR: Arginase; TIGRFAM: Arginase, subgroup; IMG reference gene:2504121818; PFAM: Arginase family; TIGRFAM: arginase YP_004255241.1 COGs: COG4696 conserved hypothetical protein; KEGG: dra:DR_2231 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121819; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase YP_004255242.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: dra:DR_1097 phosphoglycerate mutase, putative; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1; SPTR: Phosphoglycerate mutase, putative; IMG reference gene:2504121820; PFAM: Phosphoglycerate mutase family YP_004255243.1 KEGG: ddr:Deide_16530 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121821 YP_004255244.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753; KEGG: dge:Dgeo_0617 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Crotonase, core; SPTR: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; IMG reference gene:2504121822; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004255245.1 KEGG: ddr:Deide_17250 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121823; PFAM: Prolyl oligopeptidase family YP_004255246.1 COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616:IPR020617:IPR002155; KEGG: dge:Dgeo_0618 acetyl-CoA C-acyltransferase; PFAM: Thiolase, N-terminal; Thiolase, C-terminal; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA C-acyltransferase; TIGRFAM: Thiolase; IMG reference gene:2504121824; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_004255247.1 KEGG: dra:DR_2483 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121825 YP_004255248.1 InterPro IPR002559; KEGG: dge:Dgeo_2989 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein; IMG reference gene:2504121828; PFAM: Transposase DDE domain YP_004255249.1 KEGG: dra:DR_1779 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121829 YP_004255250.1 COGs: COG2319 FOG: WD40 repeat; KEGG: dra:DR_2484 WD repeat-containing protein; SPTR: Uncharacterized WD repeat-containing protein DR_2484; IMG reference gene:2504121830 YP_004255251.1 KEGG: mau:Micau_5197 cellulose-binding family II protein; SPTR: Cellulose-binding family II; IMG reference gene:2504121831 YP_004255252.1 COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006674:IPR006675; KEGG: ddr:Deide_19520 putative hydrolase, HD superfamily; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: Putative hydrolase, HD superfamily; TIGRFAM: Uncharacterised protein family HDIG; IMG reference gene:2504121832; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004255253.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR007173; KEGG: sna:Snas_0567 FAD-linked oxidoreductase; PFAM: FAD linked oxidase, N-terminal; D-arabinono-1,4-lactone oxidase; SPTR: FAD-dependent oxidoreductase; IMG reference gene:2504121833; PFAM: D-arabinono-1,4-lactone oxidase; FAD binding domain YP_004255254.1 COGs: COG1092 SAM-dependent methyltransferase; KEGG: ddr:Deide_17230 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121834; PFAM: S-adenosylmethionine-dependent methyltransferase YP_004255255.1 KEGG: ang:An08g10770 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121835 YP_004255256.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: dra:DR_A0349 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504121836; PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: ABC transporter, permease/ATP-binding protein YP_004255257.1 COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR001327; KEGG: rrs:RoseRS_4211 monooxygenase, FAD-binding; PFAM: Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; SPTR: Zeaxanthin epoxidase; IMG reference gene:2504121837; PFAM: FAD binding domain YP_004255258.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dra:DR_1026 oxidoreductase; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Oxidoreductase; IMG reference gene:2504121838; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain YP_004255259.1 COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804; KEGG: dge:Dgeo_1166 isocitrate/isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; IMG reference gene:2504121839; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type YP_004255260.1 KEGG: dge:Dgeo_1167 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121840 YP_004255261.1 KEGG: dra:DR_1641 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121841; PFAM: Protein of unknown function (DUF664) YP_004255262.1 KEGG: dra:DR_0887 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121842 YP_004255263.1 COGs: COG1159 GTPase; HAMAP: GTP-binding protein Era; InterPro IPR002917:IPR004044:IPR005225:IPR005662; KEGG: dge:Dgeo_1825 GTP-binding protein Era; PFAM: GTP-binding protein, HSR1-related; K Homology, type 2; SPTR: GTP-binding protein era homolog; TIGRFAM: GTP-binding protein Era; Small GTP-binding protein; IMG reference gene:2504121843; PFAM: KH domain; GTPase of unknown function; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain YP_004255264.1 COGs: COG0101 Pseudouridylate synthase; HAMAP: Pseudouridine synthase I, TruA; InterPro IPR020097:IPR001406; KEGG: dge:Dgeo_0037 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; PRIAM: tRNA-pseudouridine synthase I; SPTR: tRNA pseudouridine synthase A; TIGRFAM: Pseudouridine synthase I, TruA; IMG reference gene:2504121844; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_004255265.1 KEGG: dge:Dgeo_0039 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121845 YP_004255266.1 KEGG: vcn:VOLCADRAFT_97335 hypothetical protein; SPTR: Apolipoprotein A1/A4/E; IMG reference gene:2504121846 YP_004255267.1 COGs: COG0261 Ribosomal protein L21; HAMAP: Ribosomal protein L21; InterPro IPR001787; KEGG: dra:DR_0086 ribosomal protein L21; PFAM: Ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: Ribosomal protein L21; IMG reference gene:2504121847; PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_004255268.1 COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: dge:Dgeo_2217 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27; IMG reference gene:2504121848; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_004255269.1 COGs: COG0536 GTPase; HAMAP: GTP-binding protein Obg/CgtA; InterProIPR006169:IPR002917:IPR015349:IPR014100:IPR 005225; KEGG: dge:Dgeo_2218 GTPase ObgE; PFAM: GTP1/OBG subdomain; GTP-binding protein, HSR1-related; GTP-binding protein GTP1/OBG, C-terminal; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; Small GTP-binding protein; GTP-binding protein GTP1/OBG, C-terminal; IMG reference gene:2504121849; PFAM: GTPase of unknown function; Domain of unknown function (DUF1967); GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; Obg family GTPase CgtA, C-terminal extension; small GTP-binding protein domain YP_004255270.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: dge:Dgeo_0048 permease YjgP/YjgQ; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/YjgQ; IMG reference gene:2504121850; PFAM: Predicted permease YjgP/YjgQ family YP_004255271.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: dge:Dgeo_0049 permease YjgP/YjgQ; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/YjgQ; IMG reference gene:2504121851; PFAM: Predicted permease YjgP/YjgQ family YP_004255272.1 KEGG: dge:Dgeo_0265 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121852 YP_004255273.1 KEGG: ddr:Deide_05350 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121853; PFAM: Protein of unknown function (DUF1569) YP_004255274.1 KEGG: vcn:VOLCADRAFT_93310 RegA-like protein RlsE; SPTR: RegA-like protein RlsE; IMG reference gene:2504121854 YP_004255275.1 COGs: COG0172 Seryl-tRNA synthetase; HAMAP: Seryl-tRNA synthetase, class IIa; InterPro IPR015866:IPR002314:IPR002317; KEGG: dra:DR_1276 seryl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Seryl-tRNA synthetase, class IIa, N-terminal; PRIAM: Serine--tRNA ligase; SPTR: Seryl-tRNA synthetase; TIGRFAM: Seryl-tRNA synthetase, class IIa; IMG reference gene:2504121855; PFAM: tRNA synthetase class II core domain (G, H, P, S and T); Seryl-tRNA synthetase N-terminal domain; TIGRFAM: seryl-tRNA synthetase YP_004255276.1 COGs: COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; HAMAP: Glu-tRNAGln amidotransferase, C subunit; InterPro IPR003837; KEGG: dge:Dgeo_0933 aspartyl/glutamyl-tRNA amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase, C subunit; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; TIGRFAM: Glu-tRNAGln amidotransferase, C subunit; IMG reference gene:2504121856; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit YP_004255277.1 COGs: COG1495 Disulfide bond formation protein DsbB; InterPro IPR003752; KEGG: ddr:Deide_12730 putative disulphide bond formation protein DsbB (BdbC) (disulfide oxidoreductase) (thiol-disulfide oxidoreductase); PFAM: Disulphide bond formation protein DsbB/BdbC; SPTR: Putative Disulphide bond formation protein DsbB (BdbC) (Disulfide oxidoreductase) (Thiol-disulfide oxidoreductase); IMG reference gene:2504121857; PFAM: Disulfide bond formation protein DsbB YP_004255278.1 COGs: COG1651 Protein-disulfide isomerase; KEGG: dra:DR_0753 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121858; PFAM: DSBA-like thioredoxin domain YP_004255279.1 KEGG: dge:Dgeo_0693 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121859 YP_004255280.1 COGs: COG0178 Excinuclease ATPase subunit; HAMAP: Excinuclease ABC, A subunit; InterPro IPR003439:IPR003593:IPR004602; KEGG: ddr:Deide_12760 excinuclease ABC subunit A; PFAM: ABC transporter-like; SPTR: Putative UvrABC system protein A (Excinuclease ABC, subunit A); TIGRFAM: Excinuclease ABC, A subunit; IMG reference gene:2504121860; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004255281.1 COGs: COG1418 HD superfamily hydrolase; HAMAP: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; InterProIPR018111:IPR006674:IPR004087:IPR003607:IPR 017705:IPR006675; KEGG: dge:Dgeo_0162 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; K Homology, type 1, subgroup; SMART: Metal-dependent phosphohydrolase, HD domain; K Homology; SPTR: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Uncharacterised protein family HDIG; IMG reference gene:2504121861; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG YP_004255282.1 KEGG: nfa:nfa22330 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121862 YP_004255283.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR007891:IPR003660:IPR000160; KEGG: ddr:Deide_18070 putative diguanylate-cyclase; PFAM: Diguanylate cyclase, predicted; CHASE3; HAMP linker domain; SMART: Diguanylate cyclase, predicted; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504121864; PFAM: HAMP domain; GGDEF domain; CHASE3 domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004255284.1 KEGG: dra:DR_1901 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121865 YP_004255285.1 KEGG: dra:DR_1900 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121866 YP_004255286.1 COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: dra:DR_A0257 ankyrin-related protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat; SPTR: Ankyrin-related protein; IMG reference gene:2504121867; PFAM: Ankyrin repeat YP_004255287.1 KEGG: dge:Dgeo_1214 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121868; PFAM: Protein of unknown function (DUF2834) YP_004255288.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); HAMAP: CTP synthase; InterPro IPR017456:IPR000991:IPR004468; KEGG: dra:DR_1573 CTP synthetase; PFAM: CTP synthase, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; IMG reference gene:2504121869; PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase YP_004255289.1 KEGG: saq:Sare_2075 binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504121870 YP_004255290.1 COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: dge:Dgeo_2155 malate dehydrogenase; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SMART: Malic enzyme, NAD-binding; SPTR: Malate dehydrogenase (Oxaloacetate decarboxylating) (NADP+); IMG reference gene:2504121871; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_004255291.1 COGs: COG5496 thioesterase; KEGG: dge:Dgeo_2156 thioesterase-like protein; SPTR: Thioesterase-like protein; IMG reference gene:2504121872 YP_004255292.1 COGs: COG1295 membrane protein; InterPro IPR004664:IPR017039; KEGG: dra:DR_2609 BrkB protein, putative; PFAM: Ribonuclease BN-related; SPTR: BrkB protein, putative; TIGRFAM: Ribonuclease BN; IMG reference gene:2504121873; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_004255293.1 COGs: COG0496 acid phosphatase; HAMAP: Survival protein SurE-like phosphatase/nucleotidase; InterPro IPR002828; KEGG: dra:DR_2397 stationary phase survival protein SurE; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: 5'-nucleotidase surE; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase; IMG reference gene:2504121874; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE YP_004255294.1 COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: dge:Dgeo_2219 peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PRIAM: Peptidylprolyl isomerase; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504121875; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004255295.1 COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: dra:DR_2288 hypothetical protein; PFAM: Appr-1-p processing; SMART: Appr-1-p processing; SPTR: UPF0189 protein DR_2288; IMG reference gene:2504121876; PFAM: Macro domain YP_004255296.1 COGs: COG0194 Guanylate kinase; HAMAP: Guanylate kinase, sub-group; InterPro IPR008144:IPR008145:IPR017665; KEGG: ddr:Deide_23190 guanylate kinase; PFAM: Guanylate kinase; PRIAM: Guanylate kinase; SMART: Guanylate kinase/L-type calcium channel; SPTR: Putative guanylate kinase (GMP kinase, guanosine monophosphate kinase, deoxyguanylate kinase); TIGRFAM: Guanylate kinase, sub-group; IMG reference gene:2504121877; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_004255297.1 KEGG: dge:Dgeo_2285 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121878 YP_004255298.1 COGs: COG2013 conserved hypothetical protein; InterPro IPR002838; KEGG: dge:Dgeo_2326 hypothetical protein; PFAM: Protein of unknown function DUF124; SPTR: Putative uncharacterized protein; IMG reference gene:2504121879; PFAM: Protein of unknown function DUF124 YP_004255299.1 InterPro IPR012827; KEGG: msv:Mesil_1871 hemerythrin-like metal-binding protein; SPTR: Hemerythrin-like metal-binding protein; TIGRFAM: Haemerythrin-like, metal-binding; IMG reference gene:2504121880; TIGRFAM: hemerythrin-like metal-binding domain YP_004255300.1 COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476:IPR005478; KEGG: dge:Dgeo_2283 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; TIGRFAM: Transketolase, bacterial-like; IMG reference gene:2504121881; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast YP_004255301.1 COGs: COG0400 esterase; InterPro IPR003140; KEGG: dra:DR_0657 serine esterase, putative; PFAM: Phospholipase/carboxylesterase; SPTR: Serine esterase, putative; IMG reference gene:2504121883; PFAM: Phospholipase/Carboxylesterase YP_004255302.1 InterPro IPR002559; KEGG: ddr:Deide_06540 putative transposase; PFAM: Transposase, IS4-like; SPTR: Putative transposase; IMG reference gene:2504121885; PFAM: Transposase DDE domain YP_004255303.1 InterPro IPR002559; KEGG: dra:DR_B0117 transposase, putative; PFAM: Transposase, IS4-like; SPTR: Transposase, putative; IMG reference gene:2504121888; PFAM: Transposase DDE domain YP_004255304.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481:IPR005479:IPR005480:IPR006275; KEGG: dge:Dgeo_2070 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; IMG reference gene:2504121890; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004255305.1 KEGG: cdu:CD36_03510 ATF1-like transcription factor, putative; SPTR: Merozoite surface protein 2; IMG reference gene:2504121891 YP_004255306.1 COGs: COG2823 periplasmic or secreted lipoprotein; InterPro IPR007055:IPR014004; KEGG: dge:Dgeo_0141 transport-associated; PFAM: Transport-associated; SMART: Transport-associated and nodulation domain, bacteria; SPTR: Signaling BON domain protein, osmotic stress response related; IMG reference gene:2504121892; PFAM: Putative phospholipid-binding domain YP_004255307.1 COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: dra:DR_0674 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; IMG reference gene:2504121893; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase YP_004255308.1 COGs: COG0165 Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; InterPro IPR022761:IPR009049; KEGG: dra:DR_0678 argininosuccinate lyase; PFAM: Lyase 1, N-terminal; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase; IMG reference gene:2504121894; PFAM: Lyase; TIGRFAM: argininosuccinate lyase YP_004255309.1 KEGG: mes:Meso_2451 formate dehydrogenase gamma subunit; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504121895 YP_004255310.1 COGs: COG4362 Nitric oxide synthase oxygenase domain; InterPro IPR004030; KEGG: ddr:Deide_13130 putative nitric-oxide synthase; PFAM: Nitric oxide synthase, oxygenase domain; PRIAM: Nitric-oxide synthase; SPTR: Nitric oxide synthase oxygenase; IMG reference gene:2504121896; PFAM: Nitric oxide synthase, oxygenase domain YP_004255311.1 IMG reference gene:2504121897 YP_004255312.1 KEGG: dra:DR_2286 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121898 YP_004255313.1 IMG reference gene:2504121900 YP_004255314.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: dra:DR_0240 hypothetical protein; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Putative uncharacterized protein; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504121901; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004255315.1 KEGG: ddr:Deide_20821 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121902 YP_004255316.1 COGs: COG0262 Dihydrofolate reductase; InterPro IPR002734; KEGG: mmi:MMAR_2852 hypothetical protein; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504121903; PFAM: RibD C-terminal domain YP_004255317.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; HAMAP: Excinuclease ABC, B subunit; InterProIPR006935:IPR001650:IPR001943:IPR014001:IPR 004807; KEGG: ddr:Deide_03120 excinuclease ABC subunit B; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: UvrABC system protein B; TIGRFAM: Excinuclease ABC, B subunit; IMG reference gene:2504121904; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit YP_004255318.1 KEGG: dra:DR_0404 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121906 YP_004255319.1 InterPro IPR004843; KEGG: dra:DR_1260 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121907; PFAM: Calcineurin-like phosphoesterase YP_004255320.1 COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR006042; KEGG: dra:DR_2280 uracil permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Uracil permease; TIGRFAM: Xanthine/uracil permease; IMG reference gene:2504121908; PFAM: Permease family; TIGRFAM: uracil-xanthine permease YP_004255321.1 KEGG: dge:Dgeo_1181 hypothetical protein; SPTR: Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabZ; IMG reference gene:2504121909 YP_004255322.1 COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; HAMAP: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; InterPro IPR013114:IPR010084; KEGG: dge:Dgeo_1182 (3R)-hydroxymyristoyl-ACP dehydratase; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; TIGRFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; IMG reference gene:2504121910; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ YP_004255323.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: dge:Dgeo_1183 permease YjgP/YjgQ; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/YjgQ; IMG reference gene:2504121911; PFAM: Predicted permease YjgP/YjgQ family YP_004255324.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR009695:IPR007235; KEGG: dge:Dgeo_1184 monogalactosyldiacylglycerol synthase; PFAM: Monogalactosyldiacylglycerol synthase; Glycosyl transferase, family 28, C-terminal; SPTR: Monogalactosyldiacylglycerol synthase; IMG reference gene:2504121912; PFAM: Glycosyltransferase family 28 C-terminal domain; Monogalactosyldiacylglycerol (MGDG) synthase YP_004255325.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: dge:Dgeo_1185 polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504121913; PFAM: Polysaccharide deacetylase YP_004255326.1 HAMAP: Twin-arginine translocation protein TatA/E; InterPro IPR003369:IPR006312; KEGG: ddr:Deide_07530 putative twin-arginine translocation protein, TatA/E family; PFAM: Bacterial sec-independent translocation protein MttA/Hcf106; SPTR: Sec-independent protein translocase protein tatA/E homolog; TIGRFAM: Twin-arginine translocation protein TatA/E; IMG reference gene:2504121914; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004255327.1 COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033:IPR019822; KEGG: ddr:Deide_07520 putative sec-independent protein translocase protein TatC; PFAM: Sec-independent periplasmic protein translocase; SPTR: Putative Sec-independent protein translocase protein tatC; TIGRFAM: Twin arginine-targeting protein translocase, TatC; manually curated; IMG reference gene:2504121915; PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_004255328.1 KEGG: dra:DR_0838 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121916 YP_004255329.1 KEGG: dra:DR_2628 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121917 YP_004255330.1 COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: dra:DR_2629 hypothetical protein; PFAM: Transcription regulator PadR N-terminal-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504121918; PFAM: Transcriptional regulator PadR-like family YP_004255331.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; HAMAP: Prolipoprotein diacylglyceryl transferase; InterPro IPR001640; KEGG: dra:DR_0807 prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: Prolipoprotein diacylglyceryl transferase; IMG reference gene:2504121919; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004255332.1 COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); HAMAP: Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; InterPro IPR005835:IPR001451:IPR005882; KEGG: dge:Dgeo_1967 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; TIGRFAM: Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; IMG reference gene:2504121920; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_004255333.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: ddr:Deide_10970 hypothetical protein; PFAM: Protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2504121921; PFAM: Sulfite exporter TauE/SafE YP_004255334.1 KEGG: dge:Dgeo_1464 hypothetical protein; SPTR: Thioredoxin family protein, general stress protein ytxJ-like protein; IMG reference gene:2504121922; PFAM: Protein of unknown function (DUF2847); TIGRFAM: bacillithiol system protein YtxJ YP_004255335.1 KEGG: dge:Dgeo_1465 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121923 YP_004255336.1 KEGG: ddr:Deide_14720 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121924 YP_004255337.1 InterPro IPR003660; KEGG: dra:DR_1829 hypothetical protein; PFAM: HAMP linker domain; SMART: HAMP linker domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121925; PFAM: HAMP domain YP_004255338.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR006674:IPR007685:IPR004095:IPR003607:IPR 004811; KEGG: dge:Dgeo_1308 (p)ppGpp synthetase I, SpoT/RelA; PFAM: RelA/SpoT; Metal-dependent phosphohydrolase, HD subdomain; TGS; PRIAM: GTP diphosphokinase; SMART: RelA/SpoT; Metal-dependent phosphohydrolase, HD domain; SPTR: (P)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT protein; IMG reference gene:2504121926; PFAM: HD domain; Region found in RelA / SpoT proteins; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004255339.1 COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: dge:Dgeo_1623 ribonuclease HII; PFAM: Ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease; IMG reference gene:2504121927; PFAM: Ribonuclease HII YP_004255340.1 KEGG: xce:Xcel_1354 ABC-2 type transporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504121928 YP_004255341.1 COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: dra:DR_B0111 glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphoryl diester phosphodiesterase; IMG reference gene:2504121929; PFAM: Glycerophosphoryl diester phosphodiesterase family YP_004255342.1 InterPro IPR017136; KEGG: dge:Dgeo_1820 hypothetical protein; PFAM: Uncharacterised conserved protein UCP037205; SPTR: Zn-ribbon protein; IMG reference gene:2504121930; PFAM: Uncharacterized protein conserved in bacteria (DUF2256) YP_004255343.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005671; KEGG: dra:DR_1482 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: 2-isopropylmalate synthase; SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase, bacterial type; IMG reference gene:2504121931; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase, bacterial type YP_004255344.1 COGs: COG0065 3-isopropylmalate dehydratase large subunit; HAMAP: Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; InterPro IPR001030:IPR011826:IPR006251; KEGG: ddr:Deide_12420 3-isopropylmalate dehydratase large subunit; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; SPTR: 3-isopropylmalate dehydratase large subunit 1; TIGRFAM: Homoaconitase/3-isopropylmalate dehydratase, large subunit, subgroup; Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; IMG reference gene:2504121932; PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein YP_004255345.1 COGs: COG0066 3-isopropylmalate dehydratase small subunit; HAMAP: 3-isopropylmalate dehydratase small subunit; InterPro IPR000573:IPR011827; KEGG: dra:DR_1784 3-isopropylmalate dehydratase small subunit; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; PRIAM: (R)-2-methylmalate dehydratase; SPTR: 3-isopropylmalate dehydratase small subunit 2; TIGRFAM: 3-isopropylmalate dehydratase, small subunit, subgroup; IMG reference gene:2504121933; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_004255346.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; HAMAP: Isopropylmalate dehydrogenase; InterPro IPR001804:IPR004429; KEGG: dge:Dgeo_1033 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; TIGRFAM: Isopropylmalate dehydrogenase; IMG reference gene:2504121934; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase YP_004255347.1 InterPro IPR011701; KEGG: nda:Ndas_2910 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504121935; PFAM: Major Facilitator Superfamily YP_004255348.1 KEGG: tra:Trad_0148 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121936 YP_004255349.1 COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752:IPR003710; KEGG: dhd:Dhaf_3165 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, C-terminal; Ketopantoate reductase ApbA/PanE, N-terminal; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE; IMG reference gene:2504121937; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase YP_004255350.1 InterPro IPR000182; KEGG: dra:DR_0608 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121938; PFAM: Acetyltransferase (GNAT) family YP_004255351.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: dra:DR_0611 LuxA-related protein; PFAM: Luciferase-like, subgroup; SPTR: LuxA-related protein; IMG reference gene:2504121939; PFAM: Luciferase-like monooxygenase YP_004255352.1 InterPro IPR013211; KEGG: cyh:Cyan8802_2478 protein of unknown function DUF1555; PFAM: LVIVD; SPTR: Alkaline phosphatase-like protein; IMG reference gene:2504121940; PFAM: LVIVD repeat YP_004255353.1 InterPro IPR000182; KEGG: fri:FraEuI1c_5015 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504121941; PFAM: Acetyltransferase (GNAT) family YP_004255354.1 KEGG: dra:DR_2086 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121942; PFAM: Protein of unknown function (DUF2905) YP_004255355.1 COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109:IPR011911; KEGG: ddr:Deide_06390 putative glutaredoxin-like protein; PFAM: Glutaredoxin; SPTR: Putative glutaredoxin-like protein; TIGRFAM: Glutaredoxin-like protein, YruB; IMG reference gene:2504121943; PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein, YruB-family YP_004255356.1 KEGG: dge:Dgeo_1751 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121944 YP_004255357.1 KEGG: dge:Dgeo_1752 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121945 YP_004255358.1 KEGG: lbz:LbrM34_V2.0530 proteophosphoglycan ppg4; SPTR: Proteophosphoglycan ppg4; IMG reference gene:2504121946 YP_004255359.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: dge:Dgeo_1753 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; IMG reference gene:2504121947; PFAM: Biopolymer transport protein ExbD/TolR YP_004255360.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: dra:DR_0456 biopolymer transport protein, putative; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Biopolymer transport protein, putative; IMG reference gene:2504121948; PFAM: MotA/TolQ/ExbB proton channel family YP_004255361.1 KEGG: dra:DR_0920 M-related protein; SPTR: M-related protein; IMG reference gene:2504121949 YP_004255362.1 KEGG: tva:TVAG_281590 hypothetical protein; SPTR: Uncharacterized protein; IMG reference gene:2504121950 YP_004255363.1 COGs: COG0063 sugar kinase; InterPro IPR004443:IPR000631; KEGG: dge:Dgeo_1145 YjeF-related protein-like protein; PFAM: YjeF-related protein, N-terminal; Uncharacterised protein family, carbohydrate kinase-related; SPTR: YjeF-related protein, sugar kinase of the RbsK family; TIGRFAM: Uncharacterised protein family, carbohydrate kinase-related; YjeF-related protein, N-terminal; IMG reference gene:2504121951; PFAM: Carbohydrate kinase; YjeF-related protein N-terminus; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related YP_004255364.1 InterPro IPR013105:IPR011717:IPR019734; KEGG: ddr:Deide_10480 putative tetratricopeptide repeat domain protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-4; SMART: Tetratricopeptide repeat; SPTR: Putative tetratricopeptide repeat domain protein; IMG reference gene:2504121952 YP_004255365.1 KEGG: ddr:Deide_10460 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121953 YP_004255366.1 COGs: COG5322 dehydrogenase; InterPro IPR003811:IPR006151; KEGG: dge:Dgeo_1012 hypothetical protein; PFAM: Glycerol-3-phosphate acyltransferase, bacteria; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: Membrane domain and Glutamyl-tRNAGlu reductase-like NAD(P) binding domain; IMG reference gene:2504121954; PFAM: Domain of unknown function (DUF205); Shikimate / quinate 5-dehydrogenase YP_004255367.1 COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: dge:Dgeo_1011 hypothetical protein; SMART: Phospholipase D/Transphosphatidylase; SPTR: Phospholipase D-like domains; IMG reference gene:2504121955 YP_004255368.1 COGs: COG0761 Penicillin tolerance protein; HAMAP: LytB protein; InterPro IPR003451; KEGG: dge:Dgeo_1010 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: LytB protein; IMG reference gene:2504121956; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) YP_004255369.1 KEGG: bpr:GBP346_A3796 hypothetical protein; SPTR: Putative membrane protein; IMG reference gene:2504121957 YP_004255370.1 InterPro IPR006076; KEGG: dra:DR_0571 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121958; PFAM: FAD dependent oxidoreductase YP_004255371.1 COGs: COG2385 Sporulation protein and related protein; InterPro IPR013693:IPR013486; KEGG: dge:Dgeo_1767 SpoIID/LytB domain-containing protein; PFAM: Sporulation stage II protein D, amidase enhancer LytB N-terminal; SPTR: SpoIID-like protein; TIGRFAM: Sporulation stage II protein D, amidase enhancer LytB; IMG reference gene:2504121959; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain YP_004255372.1 KEGG: dge:Dgeo_1768 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121960 YP_004255373.1 KEGG: dra:DR_0574 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121961 YP_004255374.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: dge:Dgeo_1186 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; manually curated; IMG reference gene:2504121962; PFAM: Methyltransferase domain YP_004255375.1 COGs: COG0456 Acetyltransferase; InterPro IPR000182; KEGG: dra:DR_0244 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121964; PFAM: Acetyltransferase (GNAT) family YP_004255376.1 COGs: COG1166 Arginine decarboxylase (spermidine biosynthesis); HAMAP: Arginine decarboxylase; InterPro IPR022644:IPR022643:IPR002985; KEGG: dge:Dgeo_1771 arginine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, N-terminal; Orn/DAP/Arg decarboxylase 2, C-terminal; PRIAM: Arginine decarboxylase; SPTR: Arginine decarboxylase; TIGRFAM: Arginine decarboxylase; IMG reference gene:2504121965; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: arginine decarboxylase, biosynthetic YP_004255377.1 InterPro IPR004360:IPR017515; KEGG: ddr:Deide_16310 putative glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; TIGRFAM: Methylmalonyl-CoA epimerase; IMG reference gene:2504121966; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase YP_004255378.1 KEGG: lma:LmjF35.0290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121967 YP_004255379.1 KEGG: ddr:Deide_16690 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121968 YP_004255380.1 COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: dra:DR_1456 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Probable ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504121969; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004255381.1 KEGG: mrb:Mrub_2970 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121970 YP_004255382.1 KEGG: dra:DR_2310 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121971 YP_004255383.1 COGs: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase; InterPro IPR017941; KEGG: dge:Dgeo_0455 Rieske (2Fe-2S) region; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske (2Fe-2S) region; IMG reference gene:2504121972; PFAM: Rieske [2Fe-2S] domain YP_004255384.1 COGs: COG4187 Arginine degradation protein (predicted deacylase); InterPro IPR002933; KEGG: oan:Oant_3500 peptidase M20; PFAM: Peptidase M20; SPTR: Peptidase M20; IMG reference gene:2504121973; PFAM: Peptidase family M20/M25/M40 YP_004255385.1 COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: rer:RER_25580 fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; IMG reference gene:2504121974; PFAM: AMP-binding enzyme YP_004255386.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone DnaJ; InterPro IPR001623:IPR001305:IPR002939:IPR012724; KEGG: dra:DR_1424 chaperone protein DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich domain; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; TIGRFAM: Chaperone DnaJ; IMG reference gene:2504121975; PFAM: DnaJ domain; DnaJ C terminal region; DnaJ central domain (4 repeats); TIGRFAM: chaperone protein DnaJ YP_004255387.1 KEGG: ade:Adeh_3329 putative Vgr-related protein; SPTR: Integral membrane protein, DUF6; IMG reference gene:2504121976 YP_004255388.1 COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002305:IPR002306; KEGG: dge:Dgeo_0450 tryptophanyl-tRNA synthetase II; PFAM: Aminoacyl-tRNA synthetase, class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Tryptophanyl-tRNA synthetase; TIGRFAM: Tryptophanyl-tRNA synthetase, class Ib; IMG reference gene:2504121977; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_004255389.1 KEGG: pno:SNOG_10811 hypothetical protein; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504121978 YP_004255390.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; HAMAP: L-threonine 3-dehydrogenase; InterPro IPR013154:IPR013149:IPR020843:IPR004627; KEGG: dge:Dgeo_0449 L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; PRIAM: L-threonine 3-dehydrogenase; SMART: Polyketide synthase, enoylreductase; SPTR: L-threonine 3-dehydrogenase; TIGRFAM: L-threonine 3-dehydrogenase; IMG reference gene:2504121979; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: L-threonine 3-dehydrogenase; 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase YP_004255391.1 KEGG: ddr:Deide_07560 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121980 YP_004255392.1 KEGG: dra:DR_1663 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121981 YP_004255393.1 COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: dge:Dgeo_0447 hypothetical protein; PFAM: Nucleoside phosphorylase domain; SPTR: 5'-methylthioadenosine S-adenosylhomocysteine nucleosidase related protein; TIGRFAM: Futalosine nucleosidase; IMG reference gene:2504121982; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase YP_004255394.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881:IPR002931; KEGG: ddr:Deide_16280 putative transglutaminase/protease-like protein; PFAM: Transglutaminase-like; Domain of unknown function DUF58; SMART: Transglutaminase-like; SPTR: Putative Transglutaminase/protease-like protein; IMG reference gene:2504121983; PFAM: Transglutaminase-like superfamily; Protein of unknown function DUF58; Domain of unknown function (DUF3488) YP_004255395.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR011703; KEGG: ddr:Deide_16290 putative MoxR-like ATPase; PFAM: ATPase, AAA-3; SPTR: Putative MoxR-like ATPase; IMG reference gene:2504121984; PFAM: ATPase family associated with various cellular activities (AAA) YP_004255396.1 KEGG: cre:CHLREDRAFT_117459 dynein heavy chain 7; SPTR: Putative uncharacterized protein; IMG reference gene:2504121985 YP_004255397.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020842:IPR002198; KEGG: ddr:Deide_2p02251 putative short-chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Putative short-chain dehydrogenase; IMG reference gene:2504121986; PFAM: short chain dehydrogenase YP_004255398.1 KEGG: pmf:P9303_28481 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121988 YP_004255399.1 COGs: COG2411 conserved hypothetical protein; InterPro IPR007374; KEGG: sen:SACE_2231 hypothetical protein; PFAM: ASCH domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121989; PFAM: ASCH domain YP_004255400.1 COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR006589:IPR011837:IPR004193:IPR006047; KEGG: dge:Dgeo_0541 glycogen debranching protein GlgX; PFAM: Glycoside hydrolase, family 13, N-terminal; Glycosyl hydrolase, family 13, catalytic domain; PRIAM: Isoamylase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Glycogen debranching enzyme GlgX; TIGRFAM: Glycogen debranching enzyme; IMG reference gene:2504121990; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glycogen debranching enzyme GlgX YP_004255401.1 KEGG: ddr:Deide_16551 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121991 YP_004255402.1 KEGG: sjp:SJA_C1-25410 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121992 YP_004255403.1 KEGG: lif:LinJ14.1210 kinesin K39; SPTR: Putative uncharacterized protein; IMG reference gene:2504121993 YP_004255404.1 KEGG: axy:AXYL_03216 spermine synthase; SPTR: C-type cytochrome biogenesis protein; IMG reference gene:2504121994 YP_004255405.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR002986:IPR022644:IPR022643; KEGG: sth:STH1810 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, N-terminal; Orn/DAP/Arg decarboxylase 2, C-terminal; PRIAM: Diaminopimelate decarboxylase; SPTR: Diaminopimelate decarboxylase; TIGRFAM: Diaminopimelate decarboxylase; IMG reference gene:2504121995; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_004255406.1 COGs: COG3224 conserved hypothetical protein; InterPro IPR007138; KEGG: dra:DR_2141 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121996; PFAM: Antibiotic biosynthesis monooxygenase YP_004255407.1 COGs: COG3440 restriction endonuclease; InterPro IPR003105:IPR003615; KEGG: dra:DR_1533 hypothetical protein; PFAM: SRA-YDG; SMART: SRA-YDG; HNH nuclease; SPTR: Putative uncharacterized protein; IMG reference gene:2504121997; PFAM: YDG/SRA domain; HNH endonuclease YP_004255408.1 COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterProIPR014001:IPR001650:IPR003711:IPR011545:IPR 005118; KEGG: dge:Dgeo_0545 transcription factor CarD; PFAM: Transcription factor CarD; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Transcription-repair-coupling factor domain; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Transcription factor CarD; IMG reference gene:2504121998; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd) YP_004255409.1 COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: asa:ASA_1900 sodium:alanine symporter family protein; PFAM: Sodium:alanine symporter; SPTR: Amino-acid carrier protein AlsT; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2504121999; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_004255410.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140; KEGG: dge:Dgeo_0793 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PRIAM: Glyoxylate reductase (NADP(+)); SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; IMG reference gene:2504122000; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_004255411.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: dge:Dgeo_0794 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504122001; PFAM: Acetyltransferase (GNAT) family YP_004255412.1 KEGG: dra:DR_1417 penicillin-binding protein 1B McrB, putative; SPTR: Penicillin-binding protein 1B McrB, putative; IMG reference gene:2504122002 YP_004255413.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: dra:DR_2192 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504122003; PFAM: ABC transporter YP_004255414.1 InterPro IPR019248; KEGG: dge:Dgeo_1300 hypothetical protein; PFAM: Domain of unknown function DUF2223; SPTR: Uncharacterized protein, predicted regulor of amylopullulanase; IMG reference gene:2504122004; PFAM: Domain of unknown function (DUF2223) YP_004255415.1 InterPro IPR000209; KEGG: dge:Dgeo_1188 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; SPTR: Peptidase S8 and S53, subtilisin, kexin, sedolisin; IMG reference gene:2504122005; PFAM: Subtilase family YP_004255416.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR002290:IPR017442; KEGG: dra:DR_1851 serine/threonine-protein kinase-related protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; SPTR: Serine/threonine-protein kinase-related protein; IMG reference gene:2504122006; PFAM: Protein kinase domain YP_004255417.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dge:Dgeo_1232 cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504122007; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004255418.1 KEGG: ctt:CtCNB1_1572 cytoplasmic membrane permease; SPTR: Cytoplasmic membrane permease; IMG reference gene:2504122008 YP_004255419.1 InterPro IPR011701; KEGG: dge:Dgeo_1389 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504122009; PFAM: Bacterial protein of unknown function (DUF894) YP_004255420.1 KEGG: dge:Dgeo_0440 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122010 YP_004255421.1 COGs: COG0024 Methionine aminopeptidase; InterPro IPR002467:IPR000994; KEGG: dge:Dgeo_1284 methionine aminopeptidase, type I; PFAM: Peptidase M24, structural domain; PRIAM: Methionyl aminopeptidase; SPTR: Methionine aminopeptidase; TIGRFAM: Peptidase M24A, methionine aminopeptidase, subfamily 1; IMG reference gene:2504122011; PFAM: Metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_004255422.1 COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: dge:Dgeo_1953 PASTA domain-containing protein; PFAM: PASTA; SMART: PASTA; SPTR: PASTA domains protein; IMG reference gene:2504122012; PFAM: PASTA domain YP_004255423.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: dra:DR_0215 aminotransferase, class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase, class V; IMG reference gene:2504122013; PFAM: Aminotransferase class-V YP_004255424.1 KEGG: msv:Mesil_2617 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122014 YP_004255425.1 COGs: COG0820 Fe-S-cluster redox enzyme; HAMAP: Ribosomal RNA large subunit methyltransferase RlmN; InterPro IPR004383:IPR007197; KEGG: dra:DR_0936 ribosomal RNA large subunit methyltransferase N; PFAM: Radical SAM; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: Ribosomal RNA large subunit methyltransferase RlmN; IMG reference gene:2504122015; PFAM: Radical SAM superfamily; TIGRFAM: 23S rRNA m2A2503 methyltransferase YP_004255426.1 InterPro IPR013229; KEGG: dra:DR_1185 S-layer-like array-related protein; PFAM: PEGA; SPTR: S-layer-like array-related protein; IMG reference gene:2504122016; PFAM: PEGA domain YP_004255427.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: dge:Dgeo_0813 hypothetical protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Lipoprotein releasing system, permease, LolC/E family; IMG reference gene:2504122017; PFAM: Predicted permease YP_004255428.1 COGs: COG3584 conserved hypothetical protein; KEGG: dra:DR_0488 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122018 YP_004255429.1 COGs: COG2363 Uncharacterized small membrane protein; InterPro IPR006696; KEGG: dra:DR_1864 hypothetical protein; PFAM: Protein of unknown function DUF423; SPTR: Putative uncharacterized protein; IMG reference gene:2504122019; PFAM: Protein of unknown function (DUF423) YP_004255430.1 COGs: COG0691 tmRNA-binding protein; HAMAP: SsrA-binding protein; InterPro IPR000037; KEGG: ddr:Deide_08770 SsrA-binding protein; PFAM: SsrA-binding protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; IMG reference gene:2504122020; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004255431.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: ddr:Deide_08780 putative cell wall hydrolase/autolysin, precursor; PFAM: Cell wall hydrolase/autolysin, catalytic; SPTR: Putative Cell wall hydrolase/autolysin,; IMG reference gene:2504122021; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004255432.1 InterPro IPR019606; KEGG: dge:Dgeo_0821 hypothetical protein; PFAM: GerMN domain; SMART: GerMN domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122022; PFAM: Sporulation and spore germination YP_004255433.1 COGs: COG1196 Chromosome segregation ATPase; InterPro IPR010935:IPR003395; KEGG: dge:Dgeo_0822 SMC protein-like protein; PFAM: RecF/RecN/SMC; SMCs flexible hinge; SMART: SMCs flexible hinge; SPTR: SMC protein; IMG reference gene:2504122023; PFAM: RecF/RecN/SMC N terminal domain; SMC proteins Flexible Hinge Domain YP_004255434.1 COGs: COG1692 conserved hypothetical protein; InterPro IPR004843; KEGG: dge:Dgeo_0662 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; IMG reference gene:2504122025; TIGRFAM: metallophosphoesterase, MG_246/BB_0505 family YP_004255435.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR013093:IPR 019489; KEGG: dra:DR_0588 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpA; IMG reference gene:2504122026; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA) YP_004255436.1 InterPro IPR000835; KEGG: bgl:bglu_2g02930 transcriptional regulator, MarR family protein; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: MarR family transcriptional regulator; IMG reference gene:2504122027; PFAM: MarR family YP_004255437.1 KEGG: sma:SAV_1294 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122028 YP_004255438.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: cpo:COPRO5265_0206 putative dihydroflavonol 4-reductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative dihydroflavonol 4-reductase; IMG reference gene:2504122029; PFAM: NAD dependent epimerase/dehydratase family YP_004255439.1 COGs: COG2127 conserved hypothetical protein; HAMAP: ATP-dependent Clp protease adaptor protein ClpS; InterPro IPR003769:IPR022935; KEGG: dra:DR_0586 ATP-dependent Clp protease adaptor protein ClpS; PFAM: Adaptor protein ClpS, core; SPTR: ATP-dependent Clp protease adapter protein ClpS; IMG reference gene:2504122030; PFAM: ATP-dependent Clp protease adaptor protein ClpS YP_004255440.1 InterPro IPR000182; KEGG: ddr:Deide_21800 putative acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acetyltransferase; IMG reference gene:2504122031; PFAM: Acetyltransferase (GNAT) family YP_004255441.1 InterPro IPR011637; KEGG: fba:FIC_02515 hypothetical protein; PFAM: Uncharacterised protein family YphA; SPTR: Putative uncharacterized protein; IMG reference gene:2504122032; PFAM: DoxX YP_004255442.1 KEGG: dge:Dgeo_0415 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122033 YP_004255443.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); HAMAP: Glutamyl-tRNA(Gln) amidotransferase, B subunit; InterPro IPR018027:IPR004413:IPR006075; KEGG: dge:Dgeo_0414 aspartyl/glutamyl-tRNA amidotransferase subunit B; PFAM: Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, N-terminal; Asn/Gln amidotransferase; SMART: Asn/Gln amidotransferase; SPTR: Glutamyl-tRNA(Gln) amidotransferase, B subunit; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase, B subunit; IMG reference gene:2504122034; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit YP_004255444.1 KEGG: kfl:Kfla_4429 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122035 YP_004255445.1 InterPro IPR003675; KEGG: dge:Dgeo_1450 abortive infection protein; PFAM: Abortive infection protein; SPTR: CAAX amino terminal protease family protein; IMG reference gene:2504122036; PFAM: CAAX amino terminal protease family YP_004255446.1 KEGG: cyj:Cyan7822_4806 50S ribosomal protein L12 honologue; SPTR: 50S ribosomal protein L12 honologue; IMG reference gene:2504122037 YP_004255447.1 COGs: COG2839 conserved hypothetical protein; InterPro IPR007403; KEGG: ddr:Deide_09330 hypothetical protein; PFAM: Protein of unknown function DUF456; SPTR: Putative uncharacterized protein; IMG reference gene:2504122038; PFAM: Protein of unknown function (DUF456) YP_004255448.1 COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR020616:IPR020617; KEGG: dra:DR_1072 acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal; Thiolase, C-terminal; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; IMG reference gene:2504122039; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_004255449.1 COGs: COG2350 conserved hypothetical protein; InterPro IPR005545; KEGG: dge:Dgeo_1442 YCII-related; PFAM: YCII-related; SPTR: YCII-related protein; IMG reference gene:2504122040; PFAM: YCII-related domain YP_004255450.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108; KEGG: dra:DR_1068 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA dehydrogenase; SPTR: Probable 3-hydroxybutyryl-CoA dehydrogenase; IMG reference gene:2504122041; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004255451.1 COGs: COG1247 Sortase and related acyltransferase; InterPro IPR000182; KEGG: dra:DR_1182 phosphinothricin acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; PRIAM: Phosphinothricin acetyltransferase; SPTR: Phosphinothricin acetyltransferase; IMG reference gene:2504122042; PFAM: Acetyltransferase (GNAT) family YP_004255452.1 SPTR: Phosphoglucosamine mutase; IMG reference gene:2504122043 YP_004255453.1 COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000640:IPR005225:IPR006298:IPR000795:IPR 004161; KEGG: ddr:Deide_11340 putative GTP-binding TypA/BipA protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SMART: Translation elongation factor EFG/EF2, C-terminal; SPTR: Putative GTP-binding TypA/BipA protein; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; IMG reference gene:2504122044; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_004255454.1 COGs: COG3342 conserved hypothetical protein; InterPro IPR010430:IPR014927; KEGG: ddr:Deide_17020 hypothetical protein; PFAM: Protein of unknown function DUF1028; Putative peptidoglycan binding; SPTR: Putative uncharacterized protein; IMG reference gene:2504122045; PFAM: Putative peptidoglycan binding domain; Family of unknown function (DUF1028) YP_004255455.1 COGs: COG0448 ADP-glucose pyrophosphorylase; HAMAP: Glucose-1-phosphate adenylyltransferase GlgC, bacterial; InterPro IPR011831:IPR005835:IPR023049; KEGG: dge:Dgeo_0861 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: Glucose-1-phosphate adenylyltransferase; TIGRFAM: Glucose-1-phosphate adenylyltransferase; IMG reference gene:2504122046; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase YP_004255456.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; HAMAP: tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022:IPR002627; KEGG: dra:DR_1690 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; IMG reference gene:2504122047; PFAM: IPP transferase; TIGRFAM: tRNA dimethylallyltransferase YP_004255457.1 COGs: COG0071 Molecular chaperone (small heat shock protein); KEGG: dra:DR_1691 heat shock protein-related protein; SPTR: Heat shock protein-related protein; IMG reference gene:2504122048; PFAM: Hsp20/alpha crystallin family YP_004255458.1 COGs: COG2501 conserved hypothetical protein; InterPro IPR002942; KEGG: ddr:Deide_05390 hypothetical protein; PFAM: RNA-binding S4; SPTR: Putative uncharacterized protein; IMG reference gene:2504122049; PFAM: S4 domain YP_004255459.1 COGs: COG3358 conserved hypothetical protein; InterPro IPR012467; KEGG: dge:Dgeo_1648 hypothetical protein; PFAM: Protein of unknown function DUF1684; SPTR: Putative uncharacterized protein; IMG reference gene:2504122050; PFAM: Protein of unknown function (DUF1684) YP_004255460.1 COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: dge:Dgeo_0938 competence protein ComF, putative; PFAM: Phosphoribosyltransferase; SPTR: Competence protein ComF, putative; IMG reference gene:2504122051; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein YP_004255461.1 COGs: COG1576 conserved hypothetical protein; HAMAP: SPOUT methyltransferase, predicted; InterPro IPR003742; KEGG: dra:DR_0619 hypothetical protein; PFAM: SPOUT methyltransferase, predicted; SPTR: Ribosomal RNA large subunit methyltransferase H; IMG reference gene:2504122052; PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH YP_004255462.1 COGs: COG0082 Chorismate synthase; InterPro IPR000453; KEGG: dra:DR_0775 chorismate synthase; PFAM: Chorismate synthase; PRIAM: Chorismate synthase; SPTR: Chorismate synthase; TIGRFAM: Chorismate synthase; IMG reference gene:2504122053; PFAM: Chorismate synthase; TIGRFAM: chorismate synthase YP_004255463.1 COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR005644:IPR004846; KEGG: dge:Dgeo_1729 type II and III secretion system protein; PFAM: Type II/III secretion system; NolW-like; SPTR: Type IV pilus assembly protein PilQ; IMG reference gene:2504122054; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein YP_004255464.1 KEGG: ddr:Deide_17630 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122055 YP_004255465.1 InterPro IPR019677; KEGG: ddr:Deide_17620 putative type IV pilus assembly protein PilO precursor; PFAM: General secretion pathway protein M; SPTR: Putative Type IV pilus assembly protein PilO; IMG reference gene:2504122056; PFAM: Pilus assembly protein, PilO YP_004255466.1 InterPro IPR007813; KEGG: ddr:Deide_17610 putative type IV pilus assembly protein PilN; PFAM: Fimbrial assembly; SPTR: Putative Type IV pilus assembly protein PilN; IMG reference gene:2504122057; PFAM: Fimbrial assembly protein (PilN) YP_004255467.1 COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR003494:IPR005883; KEGG: dra:DR_0770 fimbrial assembly protein PilM, putative; PFAM: Cell division protein FtsA domain; SMART: Cell division protein FtsA domain; SPTR: Fimbrial assembly protein PilM, putative; TIGRFAM: Type IV pilus assembly protein PilM; IMG reference gene:2504122058; PFAM: Competence protein A; Cell division protein FtsA; TIGRFAM: type IV pilus assembly protein PilM YP_004255468.1 KEGG: dge:Dgeo_1724 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122059 YP_004255469.1 COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR005863:IPR000713:IPR013221:IPR004101; KEGG: ddr:Deide_17590 putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase); PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-a lanineligase; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM: UDP-MurNAc-pentapeptide synthetase; IMG reference gene:2504122060; PFAM: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_004255470.1 COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR019986:IPR004007; KEGG: ddr:Deide_17580 putative Dak phosphatase; PFAM: Dak phosphatase; SPTR: Putative Dak phosphatase; TIGRFAM: DAK2 domain-containing protein YloV; manually curated; IMG reference gene:2504122061; PFAM: DAK2 domain; TIGRFAM: DAK2 domain fusion protein YloV YP_004255471.1 COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: dge:Dgeo_1721 hypothetical protein; PFAM: Alkaline shock protein Asp23; SPTR: Alkaline shock-like protein DUF322; IMG reference gene:2504122062; PFAM: Protein of unknown function (DUF322) YP_004255472.1 COGs: COG2041 Sulfite oxidase; InterPro IPR000572; KEGG: dge:Dgeo_1719 oxidoreductase, molybdopterin binding; PFAM: Oxidoreductase, molybdopterin-binding domain; SPTR: Oxidoreductase, molybdopterin binding; IMG reference gene:2504122063; PFAM: Oxidoreductase molybdopterin binding domain YP_004255473.1 COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; InterPro IPR005122; KEGG: dge:Dgeo_1718 uracil-DNA glycosylase superfamily protein; PFAM: Uracil-DNA glycosylase-like; SPTR: Uracil-DNA glycosylase superfamily; IMG reference gene:2504122064; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: mismatch-specific thymine-DNA glycosylate (mug) YP_004255474.1 COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: dra:DR_1177 hypothetical protein; PFAM: Peroxiredoxin, OsmC-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122065; PFAM: OsmC-like protein YP_004255475.1 COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; HAMAP: Maf-like protein; InterPro IPR003697; KEGG: dge:Dgeo_1267 Maf-like protein; PFAM: Maf-like protein; SPTR: Maf-like protein Dgeo_1267; TIGRFAM: Maf-like protein; IMG reference gene:2504122066; PFAM: Maf-like protein; TIGRFAM: MAF protein YP_004255476.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: xau:Xaut_1118 3-oxoadipate enol-lactonase; PFAM: Alpha/beta hydrolase fold-1; SPTR: 3-oxoadipate enol-lactonase; IMG reference gene:2504122067; PFAM: alpha/beta hydrolase fold YP_004255477.1 COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR011547:IPR002645; KEGG: ddr:Deide_18200 putative sulfate transporter; putative membrane protein; PFAM: Sulphate transporter; Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Putative sulfate transporter; putative membrane protein; IMG reference gene:2504122068; PFAM: Sulfate transporter family; STAS domain; TIGRFAM: high affinity sulphate transporter 1 YP_004255478.1 KEGG: fri:FraEuI1c_4533 amino acid adenylation domain protein; SPTR: Transposase; IMG reference gene:2504122069 YP_004255479.1 COGs: COG0274 Deoxyribose-phosphate aldolase; HAMAP: Deoxyribose-phosphate aldolase, type 1; InterPro IPR011343:IPR002915:IPR022979; KEGG: dge:Dgeo_1266 deoxyribose-phosphate aldolase; PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Deoxyribose-phosphate aldolase; SPTR: Deoxyribose-phosphate aldolase; TIGRFAM: Deoxyribose-phosphate aldolase; IMG reference gene:2504122070; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_004255480.1 COGs: COG1225 Peroxiredoxin; InterPro IPR000866; KEGG: dra:DR_0846 bacterioferritin comigratory protein; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Bacterioferritin comigratory protein; IMG reference gene:2504122071; PFAM: AhpC/TSA family YP_004255481.1 COGs: COG0120 Ribose 5-phosphate isomerase; HAMAP: Ribose-5-phosphate isomerase, type A, subgroup; InterPro IPR004788:IPR020672; KEGG: dra:DR_0845 ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase, type A; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose-5-phosphate isomerase A; TIGRFAM: Ribose 5-phosphate isomerase, type A; IMG reference gene:2504122072; PFAM: Ribose 5-phosphate isomerase A (phosphoriboisomerase A); TIGRFAM: ribose 5-phosphate isomerase YP_004255482.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase; InterProIPR004739:IPR001674:IPR000991:IPR011063:IPR 022955; KEGG: dra:DR_1874 GMP synthase; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA(Ile)-lysidine/2-thiocytidine synthase; PRIAM: GMP synthase (glutamine-hydrolyzing); SPTR: GMP synthase [glutamine-hydrolyzing]; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; IMG reference gene:2504122073; PFAM: Glutamine amidotransferase class-I; GMP synthase C terminal domain; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit YP_004255483.1 KEGG: dac:Daci_0764 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122074 YP_004255484.1 InterPro IPR002035; KEGG: fri:FraEuI1c_2215 von Willebrand factor type A; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor type A; IMG reference gene:2504122075; PFAM: von Willebrand factor type A domain YP_004255485.1 KEGG: fra:Francci3_2917 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122076 YP_004255486.1 InterPro IPR002575; KEGG: dge:Dgeo_1297 aminoglycoside phosphotransferase; PFAM: Aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase; IMG reference gene:2504122077; PFAM: Phosphotransferase enzyme family YP_004255487.1 KEGG: dge:Dgeo_1598 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122078 YP_004255488.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR004610:IPR001667:IPR003156; KEGG: dge:Dgeo_1599 single-stranded-DNA-specific exonuclease RecJ; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; IMG reference gene:2504122079; PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ YP_004255489.1 KEGG: dge:Dgeo_1600 hypothetical protein; SPTR: Predicted phosphosugar isomerase; IMG reference gene:2504122080 YP_004255490.1 InterPro IPR000297; KEGG: dge:Dgeo_1601 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504122082; PFAM: PPIC-type PPIASE domain YP_004255491.1 COGs: COG1354 conserved hypothetical protein; InterPro IPR003768; KEGG: dge:Dgeo_1603 hypothetical protein; PFAM: Prokaryotic chromosome segregation/condensation protein ScpA; SPTR: Putative uncharacterized protein; IMG reference gene:2504122083 YP_004255492.1 COGs: COG3881 conserved hypothetical protein; InterPro IPR007903; KEGG: dge:Dgeo_1677 PRC-barrel domain-containing protein; PFAM: PRC-barrel; SPTR: PRC-barrel domain protein; IMG reference gene:2504122084; PFAM: PRC-barrel domain YP_004255493.1 COGs: COG1668 ABC-type Na+ efflux pump permease component; InterPro IPR013525; KEGG: dge:Dgeo_1676 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-type Na+ efflux pump, permease component; IMG reference gene:2504122085 YP_004255494.1 COGs: COG4555 ABC-type Na+ transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ddr:Deide_15090 putative sodium ABC transporter, ATP-binding component NatA; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative Sodium ABC transporter, ATP-binding component NatA; IMG reference gene:2504122086; PFAM: ABC transporter YP_004255495.1 KEGG: dge:Dgeo_1671 hypothetical protein; SPTR: HTH transcriptional regulator; IMG reference gene:2504122087 YP_004255496.1 COGs: COG3870 conserved hypothetical protein; InterPro IPR010375; KEGG: dge:Dgeo_1670 hypothetical protein; PFAM: Protein of unknown function DUF970; SPTR: Nitrogen regulatory protein P-II related protein, DUF970; IMG reference gene:2504122088; PFAM: Protein of unknown function (DUF970) YP_004255497.1 COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: ddr:Deide_16750 putative histone deacetylase superfamily; PFAM: Histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Putative histone deacetylase superfamily; IMG reference gene:2504122089; PFAM: Histone deacetylase domain YP_004255498.1 COGs: COG2074 2-phosphoglycerate kinase; KEGG: dge:Dgeo_1765 2-phosphoglycerate kinase; SPTR: 2-phosphoglycerate kinase; IMG reference gene:2504122090 YP_004255499.1 InterPro IPR001647; KEGG: dge:Dgeo_1764 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504122091; PFAM: Bacterial regulatory proteins, tetR family YP_004255500.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR002482:IPR018392:IPR000064; KEGG: dge:Dgeo_1388 NLP/P60; PFAM: NLP/P60; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: NLP/P60; IMG reference gene:2504122092; PFAM: NlpC/P60 family; LysM domain YP_004255501.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; HAMAP: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; InterPro IPR005750:IPR001986; KEGG: dge:Dgeo_1386 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: Enolpyruvate transferase domain; PRIAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; IMG reference gene:2504122093; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004255502.1 COGs: COG0686 Alanine dehydrogenase; InterPro IPR008141:IPR007886:IPR007698; KEGG: dra:DR_1895 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; PRIAM: Alanine dehydrogenase; SPTR: Alanine dehydrogenase; TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; IMG reference gene:2504122094; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase YP_004255503.1 COGs: COG1522 Transcriptional regulators; InterPro IPR019888:IPR000835:IPR019887; KEGG: dge:Dgeo_0772 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type, C-terminal; HTH transcriptional regulator, MarR; SMART: Transcription regulator AsnC-type; SPTR: Transcriptional regulator, AsnC family; IMG reference gene:2504122095; PFAM: MarR family; AsnC family YP_004255504.1 COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: ddr:Deide_18040 putative peptidylprolyl isomerase, precursor (peptidyl-prolyl cis-trans isomerase) (PPIase); PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504122096; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004255505.1 COGs: COG0688 Phosphatidylserine decarboxylase; KEGG: dra:DR_1574 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122097 YP_004255506.1 KEGG: dra:DR_2083 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122098 YP_004255507.1 KEGG: ppm:PPSC2_c2752 protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122099 YP_004255508.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR017730:IPR004176:IPR003959:IPR 013093:IPR019489; KEGG: dra:DR_1046 ATP-dependent Clp protease, ATP-binding subunit ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: Chaperone protein ClpB; TIGRFAM: Chaperonin ClpB; IMG reference gene:2504122100; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_004255509.1 InterPro IPR000182; KEGG: ddr:Deide_08250 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122101; PFAM: Acetyltransferase (GNAT) family YP_004255510.1 COGs: COG0787 Alanine racemase; HAMAP: Alanine racemase; InterPro IPR000821:IPR001608:IPR011079; KEGG: dge:Dgeo_1380 alanine racemase; PFAM: Alanine racemase, C-terminal; Alanine racemase, N-terminal; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: Alanine racemase; IMG reference gene:2504122102; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase YP_004255511.1 COGs: COG0442 Prolyl-tRNA synthetase; HAMAP: Prolyl-tRNA synthetase, class IIa, eukaryotic-type; InterPro IPR016061:IPR004499:IPR002314:IPR004154; KEGG: dra:DR_1266 prolyl-tRNA synthetase; PFAM: Anticodon-binding; Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Prolyl-tRNA synthetase, class II, C-terminal; PRIAM: Proline--tRNA ligase; SMART: Prolyl-tRNA synthetase, class II, C-terminal; SPTR: Prolyl-tRNA synthetase; TIGRFAM: Prolyl-tRNA synthetase, class IIa, eukaryotic-type; IMG reference gene:2504122105; PFAM: Anticodon binding domain; Prolyl-tRNA synthetase, C-terminal; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family I YP_004255512.1 COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: dge:Dgeo_1949 NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH dehydrogenase; IMG reference gene:2504122106; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004255513.1 KEGG: dra:DR_1483 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122107 YP_004255514.1 KEGG: dra:DR_1483 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122108 YP_004255515.1 COGs: COG0850 Septum formation inhibitor; HAMAP: Septum formation inhibitor MinC; InterPro IPR005526:IPR013033; KEGG: dge:Dgeo_0673 septum formation inhibitor MinC; PFAM: Septum formation inhibitor MinC, C-terminal; SPTR: Probable septum site-determining protein minC; IMG reference gene:2504122109; PFAM: Septum formation inhibitor MinC, C-terminal domain; TIGRFAM: septum site-determining protein MinC YP_004255516.1 HAMAP: Ribosome maturation factor RimP; InterPro IPR003728; KEGG: dge:Dgeo_1233 hypothetical protein; PFAM: Ribosome maturation factor RimP; SPTR: Ribosome maturation factor rimP; IMG reference gene:2504122110; PFAM: Uncharacterised BCR, YhbC family COG0779 YP_004255517.1 COGs: COG0195 Transcription elongation factor; InterPro IPR022967:IPR010213:IPR013735; KEGG: ddr:Deide_10380 transcription elongation factor NusA; PFAM: Transcription factor NusA, N-terminal; SMART: RNA-binding domain, S1; SPTR: Putative Transcription elongation factor NusA; TIGRFAM: Transcription termination factor NusA; IMG reference gene:2504122111; PFAM: NusA N-terminal domain; TIGRFAM: transcription termination factor NusA YP_004255518.1 COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: dge:Dgeo_1235 hypothetical protein; PFAM: Protein of unknown function DUF448; SPTR: Putative uncharacterized protein; IMG reference gene:2504122112; PFAM: Protein of unknown function (DUF448) YP_004255519.1 COGs: COG0532 Translation initiation factor 2 (IF-2; GTPase); InterProIPR000178:IPR005225:IPR006847:IPR000795:IPR 004161; KEGG: dra:DR_1799 translation initiation factor IF-2; PFAM: Protein synthesis factor, GTP-binding; Translation initiation factor IF-2, N-terminal; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Translation initiation factor IF-2; TIGRFAM: Translation initiation factor aIF-2, bacterial-like; Small GTP-binding protein; IMG reference gene:2504122113; PFAM: Elongation factor Tu domain 2; Translation-initiation factor 2; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_004255520.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR004396:IPR002917:IPR013029; KEGG: ddr:Deide_05530 GTP-dependent nucleic acid-binding protein EngD; PFAM: Domain of unknown function DUF933; GTP-binding protein, HSR1-related; SPTR: Putative GTP-dependent nucleic acid-binding protein; TIGRFAM: Conserved hypothetical protein CHP00092; IMG reference gene:2504122117; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF YP_004255521.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: dra:DR_2264 zinc metallohydrolase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Zinc metallohydrolase, glyoxalase II family; IMG reference gene:2504122118; PFAM: Metallo-beta-lactamase superfamily YP_004255522.1 COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR008331; KEGG: ddr:Deide_21200 putative DNA protection during starvation protein Dps; PFAM: Ferritin/Dps protein; SPTR: Putative DNA protection during starvation protein Dps; manually curated; IMG reference gene:2504122119; PFAM: Ferritin-like domain YP_004255523.1 InterPro IPR004360; KEGG: xau:Xaut_3833 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase; IMG reference gene:2504122120; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004255524.1 KEGG: dra:DR_2262 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122121 YP_004255525.1 COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: dra:DR_1659 oligopeptidase A; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; PRIAM: Oligopeptidase A; SPTR: Oligopeptidase A; IMG reference gene:2504122122; PFAM: Peptidase family M3 YP_004255526.1 KEGG: ddr:Deide_14940 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122123; PFAM: Acetyltransferase (GNAT) family YP_004255527.1 KEGG: dra:DR_1127 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122124; PFAM: Toxic anion resistance protein (TelA) YP_004255528.1 COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR003018:IPR006674; KEGG: dra:DR_0719 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; GAF; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122125; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004255529.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dge:Dgeo_0657 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504122126; PFAM: Periplasmic binding protein YP_004255530.1 InterPro IPR003088; KEGG: ddr:Deide_22760 putative cytochrome c; PFAM: Cytochrome c, class I; SPTR: Putative Cytochrome c; IMG reference gene:2504122127; PFAM: Cytochrome c YP_004255531.1 COGs: COG0853 Aspartate 1-decarboxylase; HAMAP: Aspartate decarboxylase; InterPro IPR003190; KEGG: dra:DR_0718 aspartate alpha-decarboxylase; PFAM: Aspartate decarboxylase; PRIAM: Aspartate 1-decarboxylase; SPTR: Aspartate 1-decarboxylase; TIGRFAM: Aspartate decarboxylase; IMG reference gene:2504122128; PFAM: Aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_004255532.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: ddr:Deide_21490 hypothetical protein; PFAM: Protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2504122129; PFAM: Sulfite exporter TauE/SafE YP_004255533.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR011717; KEGG: dge:Dgeo_0380 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; Tetratricopeptide TPR-4; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504122130; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004255534.1 KEGG: ank:AnaeK_0550 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; IMG reference gene:2504122131 YP_004255535.1 COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR012947:IPR002318:IPR018164:IPR003156; KEGG: dra:DR_2300 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; Phosphoesterase, DHHA1; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Alanyl-tRNA synthetase; TIGRFAM: Alanyl-tRNA synthetase, class IIc; IMG reference gene:2504122132; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase YP_004255536.1 COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR019734:IPR000160:IPR001633:IPR001440:IPR 011717; KEGG: ddr:Deide_21850 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504122133; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004255537.1 KEGG: nde:NIDE0994 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122134 YP_004255538.1 COGs: COG3947 Response regulator containing CheY-like receiver and SARP domains; InterPro IPR001789:IPR001867; KEGG: ddr:Deide_19260 putative response regulator, CheY; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Putative response regulator, CheY; IMG reference gene:2504122135; PFAM: Response regulator receiver domain; Bacterial transcriptional activator domain YP_004255539.1 COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: dra:DR_2540 hypothetical protein; PFAM: Amidohydrolase 3; SPTR: Putative uncharacterized protein; IMG reference gene:2504122136; PFAM: Amidohydrolase family YP_004255540.1 COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342; KEGG: dge:Dgeo_0610 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: Homoserine dehydrogenase; IMG reference gene:2504122137; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase YP_004255541.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR006405:IPR015977; KEGG: dge:Dgeo_1325 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: Nicotinate phosphoribosyltransferase putative; IMG reference gene:2504122138; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: putative nicotinate phosphoribosyltransferase YP_004255542.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: dge:Dgeo_1326 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504122139; PFAM: Sugar (and other) transporter YP_004255543.1 COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR012947:IPR002320:IPR004095:IPR002314:IPR 004154; KEGG: ddr:Deide_06410 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; IMG reference gene:2504122144; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TGS domain; TIGRFAM: threonyl-tRNA synthetase YP_004255544.1 KEGG: dra:DR_2305 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122146 YP_004255545.1 COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR002818; KEGG: pfl:PFL_2857 ThiJ/PfpI family protein; PFAM: ThiJ/PfpI; SPTR: ThiJ/PfpI family protein; IMG reference gene:2504122148; PFAM: DJ-1/PfpI family YP_004255546.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: bgf:BC1003_1530 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator, MerR family; IMG reference gene:2504122149; PFAM: MerR family regulatory protein; MerR, DNA binding YP_004255547.1 COGs: COG0541 Signal recognition particle GTPase; InterProIPR013822:IPR003593:IPR000897:IPR004780:IPR 004125; KEGG: dra:DR_1836 signal recognition particle protein; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; Signal recognition particle, SRP54 subunit, M-domain; SMART: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; ATPase, AAA+ type, core; SPTR: Signal recognition particle protein; TIGRFAM: Signal recognition particle, SRP; IMG reference gene:2504122150; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein YP_004255548.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: art:Arth_3264 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504122151 YP_004255549.1 COGs: COG0757 3-dehydroquinate dehydratase II; HAMAP: Dehydroquinase, class II; InterPro IPR001874; KEGG: dge:Dgeo_1733 3-dehydroquinate dehydratase; PFAM: Dehydroquinase, class II; PRIAM: 3-dehydroquinate dehydratase; SPTR: 3-dehydroquinate dehydratase; TIGRFAM: Dehydroquinase, class II; IMG reference gene:2504122152; PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II YP_004255550.1 COGs: COG0337 3-dehydroquinate synthetase; HAMAP: 3-dehydroquinate synthase AroB, subgroup; InterPro IPR016037:IPR002658; KEGG: dge:Dgeo_1732 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase AroB, subgroup; IMG reference gene:2504122153; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase YP_004255551.1 COGs: COG0703 Shikimate kinase; HAMAP: Shikimate kinase; InterPro IPR000623; KEGG: ddr:Deide_17660 shikimate kinase; PFAM: Shikimate kinase; PRIAM: Shikimate kinase; SPTR: Putative shikimate kinase; IMG reference gene:2504122154; PFAM: Shikimate kinase YP_004255552.1 KEGG: ddr:Deide_03200 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122155 YP_004255553.1 InterPro IPR000209; KEGG: dge:Dgeo_0457 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; SPTR: Peptidase S8 and S53, subtilisin, kexin, sedolisin; IMG reference gene:2504122156; PFAM: Subtilase family YP_004255554.1 COGs: COG4850 conserved hypothetical protein; InterPro IPR019236; KEGG: dge:Dgeo_0459 hypothetical protein; PFAM: Protein of unknown function DUF2183; SPTR: Predicted phosphatase of HAD fold; IMG reference gene:2504122157; PFAM: Uncharacterized conserved protein (DUF2183) YP_004255555.1 COGs: COG0557 Exoribonuclease R; InterProIPR001900:IPR022967:IPR011805:IPR004476:IPR 013223:IPR003029; KEGG: ddr:Deide_03240 putative ribonuclease R, (RNase R); PFAM: Ribonuclease II/R; Ribonuclease B, N-terminal OB domain; Ribosomal protein S1, RNA-binding domain; SMART: Ribonuclease II/R; RNA-binding domain, S1; SPTR: Putative Ribonuclease R, (RNase R); TIGRFAM: Ribonuclease R, bacterial; Ribonuclease II/ribonuclease R, bacteria; IMG reference gene:2504122158; PFAM: RNB domain; Ribonuclease B OB domain; S1 RNA binding domain; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonucleases YP_004255556.1 COGs: COG0708 Exonuclease III; InterPro IPR000097:IPR004808:IPR005135; KEGG: ddr:Deide_03250 putative exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Putative exodeoxyribonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; IMG reference gene:2504122159; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_004255557.1 KEGG: ddr:Deide_13760 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122160 YP_004255558.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR002290:IPR020635:IPR017442:IPR001258; KEGG: dge:Dgeo_0728 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; NHL repeat; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase; IMG reference gene:2504122161; PFAM: Protein kinase domain YP_004255559.1 COGs: COG2364 membrane protein; InterPro IPR003740; KEGG: dra:DR_1875 hypothetical protein; PFAM: Protein of unknown function DUF161; SPTR: Putative uncharacterized protein; IMG reference gene:2504122162; PFAM: Uncharacterized BCR, YitT family COG1284 YP_004255560.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: dra:DR_0822 short chain dehydrogenase/reductase family oxidoreductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Oxidoreductase, short-chain dehydrogenase/reductase family; IMG reference gene:2504122163; PFAM: short chain dehydrogenase YP_004255561.1 KEGG: dge:Dgeo_0616 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122164 YP_004255562.1 InterPro IPR018725; KEGG: ddr:Deide_14981 conserved hypothetical protein, precursor; PFAM: Protein of unknown function DUF2259, secreted; SPTR: Putative uncharacterized protein; IMG reference gene:2504122165; PFAM: Predicted secreted protein (DUF2259) YP_004255563.1 KEGG: ddr:Deide_06010 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122166; PFAM: Protein of unknown function (DUF2721) YP_004255564.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; HAMAP: DNA-directed RNA polymerase, subunit beta-prime; InterProIPR006592:IPR012754:IPR007080:IPR000722:IPR 007066:IPR007083:IPR007081; KEGG: dge:Dgeo_0635 DNA-directed RNA polymerase, subunit beta-prime; PFAM: RNA polymerase Rpb1, domain 1; RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; SMART: RNA polymerase, N-terminal; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, subunit beta-prime; IMG reference gene:2504122167; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form YP_004255565.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; HAMAP: DNA-directed RNA polymerase, beta subunit, bacterial-type; InterProIPR010243:IPR007644:IPR007645:IPR019462:IPR 007120:IPR007641; KEGG: dge:Dgeo_0636 DNA-directed RNA polymerase subunit beta; PFAM: DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 3; RNA polymerase, beta subunit, protrusion; DNA-directed RNA polymerase, beta subunit, external 1 domain; RNA polymerase Rpb2, domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit, bacterial-type; IMG reference gene:2504122168; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit YP_004255566.1 COGs: COG1832 CoA-binding protein; InterPro IPR003781; KEGG: dge:Dgeo_1943 CoA-binding; SMART: CoA-binding; SPTR: CoA-binding protein; IMG reference gene:2504122169 YP_004255567.1 COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; HAMAP: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; InterPro IPR004639:IPR005814; KEGG: dge:Dgeo_1942 glutamate-1-semialdehyde aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; IMG reference gene:2504122170; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase YP_004255568.1 KEGG: dra:DR_1172 hypothetical protein; SPTR: Protein DR_1172; IMG reference gene:2504122171 YP_004255569.1 KEGG: dra:DR_1615 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122172 YP_004255570.1 COGs: COG4371 membrane protein; KEGG: dge:Dgeo_1471 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122173; PFAM: Protein of unknown function (DUF1517) YP_004255571.1 InterPro IPR000326; KEGG: dge:Dgeo_1375 phosphoesterase, PA-phosphatase related; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase; SPTR: Phosphoesterase, PA-phosphatase related; IMG reference gene:2504122174; PFAM: PAP2 superfamily YP_004255572.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018:IPR003594:IPR013656:IPR011712; KEGG: ddr:Deide_06290 putative histidine kinase, classic; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; GAF; PAS fold-4; SMART: GAF; ATPase-like, ATP-binding domain; SPTR: Putative histidine kinase, classic; IMG reference gene:2504122175; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; PAS fold; TIGRFAM: PAS domain S-box YP_004255573.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dra:DR_0987 DNA-binding response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: DNA-binding response regulator; IMG reference gene:2504122176; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004255574.1 COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633; KEGG: ddr:Deide_19951 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504122177; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004255575.1 COGs: COG2360 Leu/Phe-tRNA-protein transferase; InterPro IPR004616; KEGG: dge:Dgeo_0708 leucyl/phenylalanyl-tRNA--protein transferase; PFAM: Leucyl/phenylalanyl-tRNA-protein transferase; PRIAM: Leucyltransferase; SPTR: Leucyltransferase; TIGRFAM: Leucyl/phenylalanyl-tRNA-protein transferase; IMG reference gene:2504122178; PFAM: Leucyl/phenylalanyl-tRNA protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA--protein transferase YP_004255576.1 COGs: COG3569 Topoisomerase IB; KEGG: dra:DR_0690 type I topoisomerase, putative; PRIAM: DNA topoisomerase; SPTR: Type I topoisomerase, putative; IMG reference gene:2504122179; PFAM: Eukaryotic DNA topoisomerase I, catalytic core YP_004255577.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR002482:IPR018392:IPR016047; KEGG: dra:DR_0848 putative lipoprotein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Lipoprotein, putative; IMG reference gene:2504122180; PFAM: Peptidase family M23; LysM domain YP_004255578.1 KEGG: mau:Micau_1709 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122181 YP_004255579.1 COGs: COG1200 RecG-like helicase; InterProIPR014001:IPR001650:IPR004609:IPR004365:IPR 011545; KEGG: dra:DR_1916 ATP-dependent DNA helicase RecG; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DNA helicase RecG; TIGRFAM: DNA helicase, ATP-dependent, RecG; IMG reference gene:2504122182; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; OB-fold nucleic acid binding domain; TIGRFAM: ATP-dependent DNA helicase RecG YP_004255580.1 KEGG: dge:Dgeo_1155 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122183 YP_004255581.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: dge:Dgeo_1140 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504122184; PFAM: short chain dehydrogenase YP_004255582.1 InterPro IPR003848; KEGG: dra:DR_0210 hypothetical protein; PFAM: Domain of unknown function DUF218; SPTR: Putative uncharacterized protein; IMG reference gene:2504122185; PFAM: DUF218 domain YP_004255583.1 InterPro IPR011466; KEGG: ddr:Deide_08930 hypothetical protein; PFAM: Protein of unknown function DUF1572; SPTR: Putative uncharacterized protein; IMG reference gene:2504122186; PFAM: Protein of unknown function (DUF1572) YP_004255584.1 COGs: COG1109 Phosphomannomutase; InterProIPR006352:IPR005844:IPR005845:IPR005846:IPR 005843; KEGG: dge:Dgeo_1664 phosphoglucosamine mutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucosamine mutase; SPTR: Phosphoglucosamine mutase; TIGRFAM: Phosphoglucosamine mutase; IMG reference gene:2504122187; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase YP_004255585.1 COGs: COG2094 3-methyladenine DNA glycosylase; HAMAP: Methylpurine-DNA glycosylase (MPG); InterPro IPR003180; KEGG: ddr:Deide_08050 putative 3-methyladenine DNA glycosylase; PFAM: Methylpurine-DNA glycosylase (MPG); SPTR: Putative 3-methyladenine DNA glycosylase; TIGRFAM: Methylpurine-DNA glycosylase (MPG); IMG reference gene:2504122188; PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: DNA-3-methyladenine glycosylase (3mg) YP_004255586.1 COGs: COG0633 Ferredoxin; InterPro IPR001041; KEGG: dra:DR_2075 ferredoxin; PFAM: Ferredoxin; SPTR: Ferredoxin; IMG reference gene:2504122189; PFAM: 2Fe-2S iron-sulfur cluster binding domain YP_004255587.1 KEGG: sse:Ssed_3680 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122190; PFAM: Bacterial inner membrane protein YP_004255588.1 COGs: COG1764 redox protein regulator of disulfide bond formation; InterPro IPR019953:IPR003718; KEGG: dra:DR_1857 organic hydroperoxide resistance protein; PFAM: Peroxiredoxin, OsmC-like protein; SPTR: Organic hydroperoxide resistance protein; TIGRFAM: Peroxiredoxin, organic hydroperoxide resistance-related; IMG reference gene:2504122191; PFAM: OsmC-like protein; TIGRFAM: peroxiredoxin, Ohr subfamily YP_004255589.1 COGs: COG1764 redox protein regulator of disulfide bond formation; InterPro IPR019953:IPR003718; KEGG: dge:Dgeo_0446 OsmC-like protein protein; PFAM: Peroxiredoxin, OsmC-like protein; SPTR: OsmC-like protein protein; TIGRFAM: Peroxiredoxin, organic hydroperoxide resistance-related; IMG reference gene:2504122192; PFAM: OsmC-like protein; TIGRFAM: peroxiredoxin, Ohr subfamily YP_004255590.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: ddr:Deide_12530 CRP/FNR family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp; Cyclic nucleotide-binding domain; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2504122193; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_004255591.1 COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205:IPR005743:IPR006691; KEGG: ddr:Deide_12520 putative DNA topoisomerase, ATP-hydrolyzing (DNA gyrase, subunit A) (DNA topoisomerase II); PFAM: DNA topoisomerase, type IIA, subunit A/C-terminal; DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit A/C-terminal; SPTR: Putative DNA topoisomerase, ATP-hydrolyzing (DNA gyrase, subunit A) (DNA topoisomerase II); TIGRFAM: DNA gyrase, subunit A; IMG reference gene:2504122194; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase, A subunit YP_004255592.1 COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: dra:DR_0995 hypothetical protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504122195; PFAM: Roadblock/LC7 domain YP_004255593.1 InterPro IPR004942; KEGG: dge:Dgeo_1019 hypothetical protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related; SPTR: Roadblock/LC7; IMG reference gene:2504122196; PFAM: Roadblock/LC7 domain YP_004255594.1 InterPro IPR004942; KEGG: ddr:Deide_12490 hypothetical protein; SMART: Dynein light chain-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504122197; PFAM: Roadblock/LC7 domain YP_004255595.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: dra:DR_0450 hypothetical protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122198; PFAM: GlcNAc-PI de-N-acetylase YP_004255596.1 COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: dra:DR_1685 ParA family chromosome partitioning ATPase; SPTR: Chromosome partitioning protein, ParA family; IMG reference gene:2504122199; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004255597.1 KEGG: dra:DR_1686 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122200 YP_004255598.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; HAMAP: Glutamyl-Q tRNA(Asp) synthetase; InterPro IPR022380:IPR020058; KEGG: dge:Dgeo_1023 glutamyl-tRNA synthetase, class Ic; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: Glutamyl-Q tRNA(Asp) synthetase; TIGRFAM: Glutamyl-Q tRNA(Asp) synthetase; IMG reference gene:2504122201; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-queuosine tRNA(Asp) synthetase YP_004255599.1 COGs: COG1950 membrane protein; InterPro IPR007165; KEGG: dge:Dgeo_0671 membrane protein of unknown function; PFAM: Membrane protein of unknown function; SPTR: Putative uncharacterized protein; IMG reference gene:2504122202; PFAM: Membrane protein of unknown function YP_004255600.1 COGs: COG0414 Panthothenate synthetase; HAMAP: Pantoate-beta-alanine ligase; InterPro IPR003721; KEGG: dge:Dgeo_0670 pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantothenate synthetase; TIGRFAM: Pantoate-beta-alanine ligase; IMG reference gene:2504122203; PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase YP_004255601.1 COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR003593:IPR006321:IPR001482; KEGG: ddr:Deide_07650 putative twitching mobility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Putative Twitching mobility protein; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504122204; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT YP_004255602.1 COGs: COG0782 Transcription elongation factor; InterPro IPR006359:IPR022691:IPR001437; KEGG: dge:Dgeo_0668 transcription elongation factor GreA; PFAM: Transcription elongation factor, GreA/GreB, N-terminal; Transcription elongation factor, GreA/GreB, C-terminal; SPTR: Transcription elongation factor GreA; TIGRFAM: Transcription elongation factor GreA; IMG reference gene:2504122205; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA YP_004255603.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: dge:Dgeo_0667 4-alpha-glucanotransferase; PFAM: Glycoside hydrolase, family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; TIGRFAM: Glycoside hydrolase, family 77; IMG reference gene:2504122206; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase YP_004255604.1 COGs: COG1755 conserved hypothetical protein; InterPro IPR007269; KEGG: dge:Dgeo_1612 isoprenylcysteine carboxyl methyltransferase; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: Isoprenylcysteine carboxyl methyltransferase; IMG reference gene:2504122207; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family YP_004255605.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: ddr:Deide_14070 putative major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative major facilitator superfamily MFS_1; IMG reference gene:2504122208; PFAM: Major Facilitator Superfamily YP_004255606.1 COGs: COG1114 Branched-chain amino acid permease; InterPro IPR004685; KEGG: mcl:MCCL_1059 branched-chain amino acid carrier protein homolog; PFAM: Branched-chain amino acid transport system II carrier protein; SPTR: Branched-chain amino acid carrier protein homolog; TIGRFAM: Branched-chain amino acid transport system II carrier protein; IMG reference gene:2504122209; PFAM: Branched-chain amino acid transport protein; TIGRFAM: branched-chain amino acid uptake carrier YP_004255607.1 COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: dra:DR_1742 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2504122210; PFAM: Phosphoglucose isomerase YP_004255608.1 KEGG: dge:Dgeo_1303 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122211 YP_004255609.1 KEGG: dge:Dgeo_1378 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122212 YP_004255610.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027; KEGG: dra:DR_0412 pyridine nucleotide-disulphide oxidoreductase, class II; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Pyridine nucleotide-disulphide oxidoreductase, class II; IMG reference gene:2504122213; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004255611.1 InterPro IPR011717; KEGG: dra:DR_2358 hypothetical protein; SPTR: Tetratricopeptide TPR_4; IMG reference gene:2504122214 YP_004255612.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR006439:IPR005834; KEGG: ddr:Deide_09100 putative haloacid dehalogenase-like hydrolase (HAD superfamily hydrolase); PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Putative haloacid dehalogenase-like hydrolase (HAD superfamily hydrolase); TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2504122215; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_004255613.1 KEGG: nhl:Nhal_4008 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122216 YP_004255614.1 COGs: COG1643 HrpA-like helicase; InterProIPR014001:IPR001650:IPR007502:IPR010225:IPR 013689; KEGG: dra:DR_0420 ATP-dependent helicase; PFAM: RNA helicase, ATP-dependent, HrpB type, C-terminal; Helicase, C-terminal; Helicase-associated domain; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; Helicase-associated domain; SPTR: ATP-dependent helicase; TIGRFAM: RNA helicase, ATP-dependent DEAH box, HrpB type; IMG reference gene:2504122217; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-terminal; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent helicase HrpB YP_004255615.1 InterPro IPR000408; KEGG: mxa:MXAN_0889 RCC1 repeat-containing protein; PFAM: Regulator of chromosome condensation, RCC1; SPTR: RCC1 repeat domain protein; IMG reference gene:2504122218 YP_004255616.1 COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620; KEGG: dge:Dgeo_1197 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504122219; PFAM: EamA-like transporter family YP_004255617.1 COGs: COG0681 Signal peptidase I; InterPro IPR000223:IPR019759; KEGG: ddr:Deide_08430 putative signal peptidase I (leader peptidase I) (SPase I) (peptidase S26A); PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Putative signal peptidase I (Leader peptidase I) (SPase I) (Peptidase S26A); TIGRFAM: Peptidase S26A, signal peptidase I; IMG reference gene:2504122220; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004255618.1 COGs: COG1550 conserved hypothetical protein; InterPro IPR007546; KEGG: dra:DR_1478 hypothetical protein; PFAM: Protein of unknown function DUF503; SPTR: Putative uncharacterized protein; IMG reference gene:2504122221; PFAM: Protein of unknown function (DUF503) YP_004255619.1 KEGG: dge:Dgeo_1074 hypothetical protein; SPTR: Heavy-metal-associated domain-containing protein; IMG reference gene:2504122222 YP_004255620.1 InterPro IPR018987; KEGG: dge:Dgeo_1073 hypothetical protein; PFAM: Protein of unknown function DUF1999; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504122223; PFAM: Protein of unknown function (DUF1999) YP_004255621.1 COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: dge:Dgeo_1070 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-dependent synthetase and ligase; IMG reference gene:2504122224; PFAM: AMP-binding enzyme YP_004255622.1 COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460; KEGG: dge:Dgeo_1068 peptidoglycan glycosyltransferase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Transpeptidase-transglycosylase component; IMG reference gene:2504122225; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase YP_004255623.1 COGs: COG0237 Dephospho-CoA kinase; HAMAP: Dephospho-CoA kinase; InterPro IPR001977; KEGG: dge:Dgeo_0828 dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; PRIAM: Dephospho-CoA kinase; SPTR: Dephospho-CoA kinase; TIGRFAM: Dephospho-CoA kinase; IMG reference gene:2504122226; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase YP_004255624.1 COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: dge:Dgeo_1203 glutamine synthetase, catalytic region; PFAM: Glutamine synthetase, catalytic domain; SPTR: Glutamine synthetase, catalytic region; IMG reference gene:2504122227; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal YP_004255625.1 COGs: COG2746 Aminoglycoside N3'-acetyltransferase; InterPro IPR003679; KEGG: dra:DR_2034 aminoglycoside N3'-acetyltransferase, type IV; PFAM: Aminoglycoside 3-N-acetyltransferase; SPTR: Aminoglycoside N3`-acetyltransferase, type IV; IMG reference gene:2504122228; PFAM: Aminoglycoside 3-N-acetyltransferase YP_004255626.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027; KEGG: dge:Dgeo_1014 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Ferredoxin--NADP(+) reductase; SPTR: NADPH-ferredoxin reductase FprA; IMG reference gene:2504122229; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004255627.1 COGs: COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase); InterPro IPR003431; KEGG: cyp:PCC8801_4199 3-phytase; PFAM: Phytase; PRIAM: 3-phytase; SPTR: 3-phytase; IMG reference gene:2504122230; PFAM: Phytase YP_004255628.1 COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR020842:IPR002198; KEGG: dge:Dgeo_0818 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504122231; PFAM: short chain dehydrogenase YP_004255629.1 KEGG: ddr:Deide_08750 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504122232 YP_004255630.1 COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518; KEGG: dra:DR_1183 nucleoside triphosphate pyrophosphohydrolase; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: MazG protein; IMG reference gene:2504122233; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_004255631.1 InterPro IPR000086; KEGG: ddr:Deide_08730 putative NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: Putative Nudix hydrolase; IMG reference gene:2504122234; PFAM: NUDIX domain YP_004255632.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: dge:Dgeo_1489 peptidase M29, aminopeptidase II; PFAM: Peptidase M29, aminopeptidase II; SPTR: Peptidase M29, aminopeptidase II; IMG reference gene:2504122235; PFAM: Thermophilic metalloprotease (M29) YP_004255633.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330; KEGG: dge:Dgeo_1491 SNF2-related; PFAM: SNF2-related; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Superfamily II DNA/RNA helicase, SNF2 family; IMG reference gene:2504122236; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004255634.1 COGs: COG4108 Peptide chain release factor RF-3; InterPro IPR004548:IPR005225:IPR000795:IPR004161; KEGG: ddr:Deide_09580 putative peptide chain release factor 3 (RF3); PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Putative Peptide chain release factor 3 (RF3); TIGRFAM: Peptide chain release factor 3; Small GTP-binding protein; IMG reference gene:2504122237; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; peptide chain release factor 3 YP_004255635.1 COGs: COG3603 conserved hypothetical protein; KEGG: dra:DR_1715 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122238 YP_004255636.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: dra:DR_0411 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short-chain dehydrogenase/reductase family; IMG reference gene:2504122239; PFAM: short chain dehydrogenase YP_004255637.1 COGs: COG0058 Glucan phosphorylase; InterPro IPR011834:IPR000811; KEGG: dge:Dgeo_1198 alpha-glucan phosphorylase; PFAM: Glycosyl transferase, family 35; PRIAM: Phosphorylase; SPTR: Alpha-glucan phosphorylase; TIGRFAM: Alpha-glucan phosphorylase; IMG reference gene:2504122240; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases YP_004255638.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003661:IPR003594; KEGG: dge:Dgeo_0908 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine kinase; IMG reference gene:2504122241; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004255639.1 KEGG: dra:DR_2090 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122242 YP_004255640.1 COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR000086:IPR001451; KEGG: dra:DR_2089 ferripyochelin-binding protein; PFAM: NUDIX hydrolase domain; Bacterial transferase hexapeptide repeat; SPTR: Ferripyochelin-binding protein; IMG reference gene:2504122243; PFAM: NUDIX domain YP_004255641.1 COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR002059; KEGG: ddr:Deide_09930 putative cold-shock DNA-binding domain protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Putative Cold-shock DNA-binding domain protein; IMG reference gene:2504122244; PFAM: 'Cold-shock' DNA-binding domain YP_004255642.1 COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; HAMAP: Folate-dependent ribothymidyl synthase; InterPro IPR004417:IPR002218; KEGG: dge:Dgeo_0484 tRNA (uracil-5-)-methyltransferase Gid; PFAM: Glucose-inhibited division protein A-related; PRIAM:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:Methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferaseTrmFO; TIGRFAM: Folate-dependent ribothymidyl synthase; IMG reference gene:2504122245; PFAM: Glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase YP_004255643.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR003660; KEGG: dge:Dgeo_1625 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; SPTR: Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2504122246; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004255644.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dge:Dgeo_1626 two component LuxR family transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504122247; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004255645.1 COGs: COG2013 conserved hypothetical protein; InterPro IPR002838; KEGG: ddr:Deide_14540 hypothetical protein; PFAM: Protein of unknown function DUF124; SPTR: Putative uncharacterized protein; IMG reference gene:2504122248; PFAM: Protein of unknown function DUF124 YP_004255646.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR005982:IPR013027; KEGG: dge:Dgeo_2772 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase; IMG reference gene:2504122249; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_004255647.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; HAMAP: Bacterial DNA recombination protein RuvA; InterPro IPR003583:IPR000085:IPR013849:IPR011114; KEGG: dge:Dgeo_0726 Holliday junction DNA helicase RuvA; PFAM: DNA helicase, Holliday junction RuvA type, domain I, bacterial; DNA helicase, Holliday junction RuvA type, domain III, C-terminal; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Bacterial DNA recombination protein RuvA; IMG reference gene:2504122250; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit YP_004255648.1 COGs: COG4292 membrane protein; InterPro IPR010640; KEGG: ddr:Deide_09350 hypothetical protein; PFAM: Low temperature requirement A; SPTR: Putative uncharacterized protein; IMG reference gene:2504122251; PFAM: Bacterial low temperature requirement A protein (LtrA) YP_004255649.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); HAMAP: NAD-dependent DNA ligase; InterProIPR013840:IPR003583:IPR001357:IPR001679:IPR 013839:IPR004150:IPR004149; KEGG: dge:Dgeo_0696 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase, adenylation; NAD-dependent DNA ligase, OB-fold; Zinc-finger, NAD-dependent DNA ligase C4-type; BRCT; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase, N-terminal; Helix-hairpin-helix DNA-binding motif, class 1; BRCT; SPTR: DNA ligase; TIGRFAM: NAD-dependent DNA ligase; IMG reference gene:2504122252; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent YP_004255650.1 COGs: COG4700 Uncharacterized protein containing a divergent form of TPR repeats; KEGG: ddr:Deide_06040 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122253 YP_004255651.1 COGs: COG0222 Ribosomal protein L7/L12; HAMAP: Ribosomal protein L7/L12; InterPro IPR000206:IPR013823; KEGG: dra:DR_2043 50S ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12, C-terminal; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: Ribosomal protein L7/L12; IMG reference gene:2504122254; PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_004255652.1 COGs: COG0244 Ribosomal protein L10; HAMAP: Ribosomal protein L10; InterPro IPR001790:IPR022973; KEGG: dge:Dgeo_0640 50S ribosomal protein L10; PFAM: Ribosomal protein L10/acidic P0; SPTR: 50S ribosomal protein L10; IMG reference gene:2504122255; PFAM: Ribosomal protein L10 YP_004255653.1 COGs: COG0081 Ribosomal protein L1; InterPro IPR005878:IPR002143; KEGG: ddr:Deide_06070 50S ribosomal protein L1; PFAM: Ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: Ribosomal protein L1, bacterial-type; IMG reference gene:2504122256; PFAM: Ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast YP_004255654.1 COGs: COG0080 Ribosomal protein L11; InterPro IPR000911:IPR006519:IPR020784:IPR020783; KEGG: dra:DR_2046 50S ribosomal protein L11; PFAM: Ribosomal protein L11, C-terminal domain; Ribosomal protein L11, N-terminal domain; SMART: Ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: Ribosomal protein L11, bacterial-type; IMG reference gene:2504122257; PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_004255655.1 COGs: COG0250 Transcription antiterminator; InterPro IPR006645:IPR005824:IPR001062; KEGG: dge:Dgeo_0643 NusG antitermination factor; PFAM: Transcription antitermination protein, NusG, N-terminal; KOW; SMART: Transcription antitermination protein, NusG, N-terminal; KOW; SPTR: Transcription antitermination protein nusG; TIGRFAM: Transcription antitermination protein, NusG; IMG reference gene:2504122258; PFAM: Transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG YP_004255656.1 InterPro IPR005807:IPR001901; KEGG: dge:Dgeo_0644 preprotein translocase subunit SecE; PFAM: Protein SecE/Sec61-gamma protein; SPTR: SecE subunit of protein translocation complex; TIGRFAM: SecE subunit of protein translocation complex; IMG reference gene:2504122259; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_004255657.1 HAMAP: Ribosomal protein L33; InterPro IPR001705; KEGG: ddr:Deide_06110 50S ribosomal protein L33; PFAM: Ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; IMG reference gene:2504122260; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004255658.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: ddr:Deide_12100 putative DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: Putative DNA helicase; IMG reference gene:2504122261; PFAM: UvrD/REP helicase YP_004255659.1 COGs: COG1660 P-loop-containing kinase; HAMAP: ATPase, P-loop-containing; InterPro IPR005337; KEGG: dge:Dgeo_0723 hypothetical protein; SPTR: UPF0042 nucleotide-binding protein Dgeo_0723; IMG reference gene:2504122262; PFAM: P-loop ATPase protein family YP_004255660.1 COGs: COG0391 conserved hypothetical protein; InterPro IPR010119:IPR002882; KEGG: dra:DR_1435 hypothetical protein; PFAM: LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052; SPTR: UPF0052 protein DR_1435; TIGRFAM: Uncharacterised protein family UPF0052; IMG reference gene:2504122263; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related YP_004255661.1 InterPro IPR001119; KEGG: dge:Dgeo_1597 S-layer-like protein region; PFAM: S-layer homology domain; SPTR: S-layer-like protein region; IMG reference gene:2504122264; PFAM: S-layer homology domain YP_004255662.1 COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941; KEGG: dge:Dgeo_1251 Rieske (2Fe-2S) region; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske (2Fe-2S) region; IMG reference gene:2504122265; PFAM: Rieske [2Fe-2S] domain YP_004255663.1 InterPro IPR019734:IPR013105; KEGG: dge:Dgeo_1250 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Cytochrome oxidase family protein containing TPR repeats; IMG reference gene:2504122266; PFAM: Cytochrome c; Tetratricopeptide repeat YP_004255664.1 COGs: COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; InterPro IPR005616; KEGG: ddr:Deide_08280 putative cytochrome c-type biogenesis protein CcmH (CycL); putative membrane protein; PFAM: Cytochrome C biogenesis protein CcmH; SPTR: Putative cytochrome c-type biogenesis protein ccmH (CycL); putative membrane protein; IMG reference gene:2504122267; PFAM: Cytochrome C biogenesis protein YP_004255665.1 COGs: COG1225 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_1248 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; IMG reference gene:2504122268; PFAM: AhpC/TSA family; TIGRFAM: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily YP_004255666.1 COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: dge:Dgeo_1247 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein; IMG reference gene:2504122269; PFAM: Cytochrome C assembly protein; TIGRFAM: c-type cytochrome biogenesis protein CcmF YP_004255667.1 COGs: COG2332 Cytochrome c-type biogenesis protein CcmE; HAMAP: CcmE/CycJ protein; InterPro IPR004329; KEGG: dge:Dgeo_1246 cytochrome c-type biogenesis protein CcmE; PFAM: CcmE/CycJ protein; SPTR: Cytochrome c-type biogenesis protein CcmE; IMG reference gene:2504122270; PFAM: CcmE YP_004255668.1 KEGG: pap:PSPA7_1069 CHASE domain-containing protein/sensory box histidine kinase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122271 YP_004255669.1 COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR002541; KEGG: ddr:Deide_08320 putative cytochrome c-type biogenesis protein CcmC; putative membrane protein; PFAM: Cytochrome c assembly protein; SPTR: Putative cytochrome c-type biogenesis protein ccmC; putative membrane protein; IMG reference gene:2504122272; PFAM: Cytochrome C assembly protein YP_004255670.1 COGs: COG0705 membrane protein; InterPro IPR022764; KEGG: dra:DR_1992 hypothetical protein; PFAM: Peptidase S54, rhomboid domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122273; PFAM: Rhomboid family YP_004255671.1 KEGG: dra:DR_2014 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122274 YP_004255672.1 COGs: COG2096 conserved hypothetical protein; InterPro IPR017858:IPR002779; KEGG: dra:DR_1638 hypothetical protein; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal; IMG reference gene:2504122275; PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase YP_004255673.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; HAMAP: 1,4-alpha-glucan-branching enzyme; InterProIPR006589:IPR006407:IPR004193:IPR006047:IPR 006048; KEGG: dra:DR_1848 glycogen branching enzyme; PFAM: Glycoside hydrolase, family 13, N-terminal; Glycosyl hydrolase, family 13, catalytic domain; Alpha-amylase, C-terminal all beta; PRIAM: 1,4-alpha-glucan branching enzyme; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: 1,4-alpha-glucan-branching enzyme; TIGRFAM: 1,4-alpha-glucan-branching enzyme; IMG reference gene:2504122276; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase YP_004255674.1 KEGG: ddr:Deide_09220 conserved hypothetical protein, precursor; putative membrane protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122277 YP_004255675.1 KEGG: dge:Dgeo_1431 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122278 YP_004255676.1 COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR005765:IPR000836; KEGG: dra:DR_1563 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: Uracil phosphoribosyl transferase; IMG reference gene:2504122279; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase YP_004255677.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR000715; KEGG: dge:Dgeo_1295 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 4; SPTR: Glycosyl transferase, family 4; IMG reference gene:2504122280; PFAM: Glycosyl transferase family 4 YP_004255678.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: ddr:Deide_11860 putative UDP-N-acetylglucosamine 2-epimerase (UDP-GlcNAc-2-epimerase); PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; IMG reference gene:2504122281; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004255679.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: dge:Dgeo_1293 diacylglycerol kinase, catalytic region; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Diacylglycerol kinase, catalytic region; IMG reference gene:2504122282; PFAM: Diacylglycerol kinase catalytic domain YP_004255680.1 COGs: COG0546 phosphatase; InterPro IPR006402:IPR006439:IPR005834; KEGG: dra:DR_0729 CbbY/CbbZ/GpH/YieH family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Hydrolase, CbbY/CbbZ/GpH/YieH family; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2504122283; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_004255681.1 COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR015413:IPR013155; KEGG: dra:DR_2174 leucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Leucine--tRNA ligase; SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; IMG reference gene:2504122284; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family YP_004255682.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: dge:Dgeo_0768 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504122285; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain YP_004255683.1 KEGG: dge:Dgeo_0767 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122286 YP_004255684.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; HAMAP: S-adenosyl-L-methionine-dependent methyltransferase, MraW; InterPro IPR002903; KEGG: dra:DR_1866 S-adenosyl-methyltransferase MraW; PFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; IMG reference gene:2504122287; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW YP_004255685.1 COGs: COG2001 conserved hypothetical protein; HAMAP: MraZ; InterPro IPR003444:IPR020603; KEGG: dra:DR_1865 cell division protein MraZ; PFAM: MraZ domain; SPTR: Protein MraZ; TIGRFAM: MraZ; IMG reference gene:2504122288; PFAM: MraZ protein; TIGRFAM: mraZ protein YP_004255686.1 KEGG: nml:Namu_2249 peptidase S15; SPTR: Peptidase S15; IMG reference gene:2504122289; PFAM: X-Pro dipeptidyl-peptidase (S15 family) YP_004255687.1 COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: ddr:Deide_12920 putative aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Cystathionine beta-lyase; SPTR: Putative aminotransferase; IMG reference gene:2504122290; PFAM: Aminotransferase class I and II YP_004255688.1 COGs: COG0775 Nucleoside phosphorylase; InterPro IPR010049:IPR000845; KEGG: dra:DR_1451 5'-methylthioadenosine/S-adenosylhomocysteine nuclosidase; PFAM: Nucleoside phosphorylase domain; PRIAM: Adenosylhomocysteine nucleosidase; SPTR: 5`-methylthioadenosine/S-adenosylhomocysteine nuclosidase; TIGRFAM: MTA/SAH nucleosidase; IMG reference gene:2504122291; PFAM: Phosphorylase superfamily; TIGRFAM: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_004255689.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: ddr:Deide_09910 putative ribosomal large subunit pseudouridine synthase, Rlu family; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Putative Ribosomal large subunit pseudouridine synthase, Rlu family; IMG reference gene:2504122292; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_004255690.1 COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: ddr:Deide_10610 putative methicillin resistance protein; putative FemAB family protein; PFAM: Methicillin resistance protein; SPTR: Putative Methicillin resistance protein; putative FemAB family protein; IMG reference gene:2504122293; PFAM: FemAB family YP_004255691.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209:IPR007280; KEGG: tra:Trad_0078 peptidase S8 and S53 subtilisin kexin sedolisin; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Peptidase, C-terminal, archaeal/bacterial; SPTR: Peptidase S8 and S53 subtilisin kexin sedolisin; IMG reference gene:2504122294; PFAM: Bacterial pre-peptidase C-terminal domain; Subtilase family YP_004255692.1 KEGG: tra:Trad_0079 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122295 YP_004255693.1 KEGG: dge:Dgeo_0746 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122296 YP_004255694.1 KEGG: dra:DR_1654 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122297 YP_004255695.1 KEGG: dge:Dgeo_1354 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122298 YP_004255696.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: tRNA-i(6)A37 modification enzyme MiaB; InterProIPR006638:IPR005839:IPR006463:IPR013848:IPR 007197:IPR002792; KEGG: dra:DR_1150 (dimethylallyl)adenosine tRNA methylthiotransferase; PFAM: Methylthiotransferase, N-terminal; Radical SAM; Deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; TIGRFAM: Methylthiotransferase; tRNA-i(6)A37 modification enzyme MiaB; IMG reference gene:2504122299; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; radical SAM methylthiotransferase, MiaB/RimO family YP_004255697.1 COGs: COG1866 Phosphoenolpyruvate carboxykinase (ATP); HAMAP: Phosphoenolpyruvate carboxykinase, ATP-utilising; InterPro IPR001272; KEGG: dge:Dgeo_1196 phosphoenolpyruvate carboxykinase; PFAM: Phosphoenolpyruvate carboxykinase, ATP-utilising; SPTR: Phosphoenolpyruvate carboxykinase [ATP]; TIGRFAM: Phosphoenolpyruvate carboxykinase, ATP-utilising; IMG reference gene:2504122300; PFAM: Phosphoenolpyruvate carboxykinase; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP) YP_004255698.1 KEGG: dge:Dgeo_1193 AlgP-related protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122301 YP_004255699.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003395:IPR004604; KEGG: dge:Dgeo_1194 DNA repair protein RecN; PFAM: RecF/RecN/SMC; SPTR: DNA repair protein RecN; TIGRFAM: DNA recombination/repair protein RecN; IMG reference gene:2504122302; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_004255700.1 KEGG: dge:Dgeo_1195 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122303 YP_004255701.1 KEGG: dge:Dgeo_1192 hypothetical protein; SPTR: Hydroxymethylbutenyl pyrophosphate reductase lytB related protein; IMG reference gene:2504122304 YP_004255702.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: dge:Dgeo_1138 Cof protein; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: HAD superfamily hydrolase; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504122305; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily YP_004255703.1 COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; HAMAP: Asparaginyl-tRNA synthetase, class IIb; InterPro IPR004522:IPR004365:IPR004364; KEGG: dge:Dgeo_1136 asparaginyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: Asparaginyl-tRNA synthetase, class IIb; IMG reference gene:2504122306; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase YP_004255704.1 COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652; KEGG: ddr:Deide_11390 triosephosphate isomerase; PFAM: Triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: Triosephosphate isomerase; IMG reference gene:2504122307; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_004255705.1 COGs: COG3631 Ketosteroid isomerase-related protein; KEGG: dra:DR_1340 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122308; PFAM: SnoaL-like polyketide cyclase YP_004255706.1 COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: ddr:Deide_11410 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; IMG reference gene:2504122309; PFAM: Phosphoglycerate kinase YP_004255707.1 COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: ddr:Deide_11420 putative glyceraldehyde-3-phosphate dehydrogenase (GAPDH); PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Putative glyceraldehyde-3-phosphate dehydrogenase (GAPDH); TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:2504122310; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_004255708.1 KEGG: dra:DR_A0303 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122311; PFAM: Protein of unknown function (DUF2946) YP_004255709.1 KEGG: dra:DR_A0302 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122312 YP_004255710.1 COGs: COG1858 Cytochrome c peroxidase; InterPro IPR004852; KEGG: dra:DR_A0301 methylamine utilization protein; PFAM: Di-haem cytochrome c peroxidase; PRIAM: Cytochrome-c peroxidase; SPTR: Methylamine utilization protein; IMG reference gene:2504122313; PFAM: Cytochrome c; Di-haem cytochrome c peroxidase YP_004255711.1 KEGG: dra:DR_A0300 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122314 YP_004255712.1 COGs: COG2372 conserved hypothetical protein homolog of Cu resistance protein CopC; InterPro IPR007348; KEGG: dge:Dgeo_1130 copper resistance protein CopC; PFAM: Copper resistance protein CopC, core; SPTR: Copper resistance protein CopC; IMG reference gene:2504122315; PFAM: Copper resistance protein CopC YP_004255713.1 InterPro IPR008457; KEGG: dra:DR_A0298 hypothetical protein; PFAM: Copper resistance D; SPTR: Putative uncharacterized protein; IMG reference gene:2504122316; PFAM: Copper resistance protein D YP_004255714.1 COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR005202:IPR002912:IPR001341; KEGG: dge:Dgeo_1127 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Transcription factor GRAS; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain; IMG reference gene:2504122317; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase YP_004255715.1 InterPro IPR018958; KEGG: epy:EpC_31580 hypothetical protein; PFAM: Cell wall assembly/cell proliferation coordinating protein, KNR4-like; SMART: Cell wall assembly/cell proliferation coordinating protein, KNR4-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504122318; PFAM: SMI1 / KNR4 family YP_004255716.1 COGs: COG1651 Protein-disulfide isomerase; InterPro IPR001853; KEGG: dge:Dgeo_0747 DsbA oxidoreductase; PFAM: DSBA-like thioredoxin domain; SPTR: DSBA oxidoreductase; IMG reference gene:2504122319; PFAM: DSBA-like thioredoxin domain YP_004255717.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR018113:IPR003352:IPR001127:IPR010973:IPR 011535; KEGG: eat:EAT1b_0191 PTS system, sucrose-specific IIBC subunit; PFAM: Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, sucrose-specific, EIIBCA component; TIGRFAM: Phosphotransferase system, sucrose-specific IIBC component; Phosphotransferase system, glucose-like IIB component; Phosphotransferase system, sugar-specific permease EIIA 1 domain; IMG reference gene:2504122320; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, sucrose-specific IIBC component; PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component; PTS system, maltose and glucose-specific subfamily, IIC component YP_004255718.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: slg:SLGD_00982 fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504122321; PFAM: pfkB family carbohydrate kinase YP_004255719.1 COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR013148:IPR013189:IPR001362:IPR006232; KEGG: mcl:MCCL_0373 sucrose-6-phosphate hydrolase homolog; PFAM: Glycosyl hydrolases family 32, N-terminal; Glycosyl hydrolase family 32, C-terminal; SMART: Glycoside hydrolase, family 32; SPTR: Sucrose-6-phosphate hydrolase; TIGRFAM: Sucrose-6-phosphate hydrolase; IMG reference gene:2504122322; PFAM: Glycosyl hydrolases family 32 C terminal; Glycosyl hydrolases family 32 N-terminal domain; TIGRFAM: sucrose-6-phosphate hydrolase YP_004255720.1 COGs: COG0060 Isoleucyl-tRNA synthetase; HAMAP: Isoleucyl-tRNA synthetase, class Ia; InterPro IPR002301:IPR002300:IPR013155; KEGG: dra:DR_1335 isoleucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Isoleucine--tRNA ligase; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: Isoleucyl-tRNA synthetase, class Ia; IMG reference gene:2504122323; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: isoleucyl-tRNA synthetase YP_004255721.1 COGs: COG0176 Transaldolase; HAMAP: Transaldolase 3B, putative; InterPro IPR022999:IPR001585:IPR004731; KEGG: ddr:Deide_11650 putative translaldolase; PFAM: Transaldolase; SPTR: Probable transaldolase; TIGRFAM: Transaldolase 3A/3B; IMG reference gene:2504122324; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family YP_004255722.1 COGs: COG1158 Transcription termination factor; InterProIPR011112:IPR011113:IPR000194:IPR003593:IPR 004665; KEGG: dge:Dgeo_1103 transcription termination factor Rho; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; Rho termination factor, RNA-binding; Rho termination factor, N-terminal; SMART: ATPase, AAA+ type, core; Rho termination factor, N-terminal; SPTR: Transcription termination factor Rho; TIGRFAM: Transcription termination factor Rho; IMG reference gene:2504122325; PFAM: Rho termination factor, N-terminal domain; Rho termination factor, RNA-binding domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: transcription termination factor Rho YP_004255723.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: dge:Dgeo_1108 alpha/beta hydrolase fold; PFAM: Alpha/beta hydrolase fold-1; SPTR: Alpha/beta hydrolase fold; manually curated; IMG reference gene:2504122326; PFAM: alpha/beta hydrolase fold YP_004255724.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013342; KEGG: ddr:Deide_11570 putative L-Ala-DL-Glu_epimerase; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; SMART: Mandelate racemase/muconate lactonizing enzyme, C-terminal; SPTR: Putative L-Ala-DL-Glu_epimerase; IMG reference gene:2504122327; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain YP_004255725.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: dge:Dgeo_1111 NLP/P60; PFAM: NLP/P60; SPTR: NLP/P60; IMG reference gene:2504122328; PFAM: NlpC/P60 family YP_004255726.1 InterPro IPR004843; KEGG: dra:DR_1360 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122329; TIGRFAM: phosphoesterase, MJ0936 family YP_004255727.1 COGs: COG0815 Apolipoprotein N-acyltransferase; HAMAP: Apolipoprotein N-acyltransferase; InterPro IPR004563:IPR003010; KEGG: dge:Dgeo_1116 apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase; TIGRFAM: Apolipoprotein N-acyltransferase; IMG reference gene:2504122330; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase YP_004255728.1 InterPro IPR011701; KEGG: hoh:Hoch_1747 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504122331; PFAM: Major Facilitator Superfamily YP_004255729.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: ddr:Deide_11490 putative diacylglycerol kinase; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Putative diacylglycerol kinase; IMG reference gene:2504122332; PFAM: Diacylglycerol kinase catalytic domain YP_004255730.1 InterPro IPR002909; KEGG: dge:Dgeo_1119 cell surface receptor IPT/TIG; PFAM: Cell surface receptor IPT/TIG; SPTR: Cell surface receptor IPT/TIG; IMG reference gene:2504122333; PFAM: IPT/TIG domain YP_004255731.1 COGs: COG0124 Histidyl-tRNA synthetase; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; InterPro IPR015807:IPR002314:IPR004154; KEGG: dge:Dgeo_1121 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; IMG reference gene:2504122334; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_004255732.1 COGs: COG0173 Aspartyl-tRNA synthetase; InterPro IPR004365:IPR004364:IPR004115:IPR004524; KEGG: dra:DR_1347 aspartyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; GAD domain; PRIAM: Aspartate--tRNA ligase; SPTR: Aspartyl-tRNA synthetase; TIGRFAM: Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type; IMG reference gene:2504122335; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type YP_004255733.1 KEGG: pap:PSPA7_3835 putative transporter; SPTR: Transport system permease protein; IMG reference gene:2504122336 YP_004255734.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; HAMAP: Excinuclease ABC, C subunit; InterProIPR004791:IPR000305:IPR001943:IPR001162:IPR 000445; KEGG: dra:DR_1354 excinuclease ABC subunit C; PFAM: Excinuclease ABC, C subunit, C-terminal; Excinuclease ABC, C subunit, N-terminal; UvrB/UvrC protein; Helix-hairpin-helix motif; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: UvrABC system protein C; TIGRFAM: Excinuclease ABC, C subunit; IMG reference gene:2504122337; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit YP_004255735.1 COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: dge:Dgeo_1100 DegV family protein; PFAM: DegV; SPTR: DegV family protein; TIGRFAM: DegV; manually curated; IMG reference gene:2504122338; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family YP_004255736.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dge:Dgeo_1099 glycosyl transferase, group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1; IMG reference gene:2504122339; PFAM: Glycosyl transferases group 1; TIGRFAM: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA YP_004255737.1 KEGG: dra:DR_1249 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122340 YP_004255738.1 COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR003781:IPR005811:IPR005810; KEGG: dra:DR_1248 succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SMART: CoA-binding; SPTR: Succinyl-CoA ligase [ADP-forming] subunit alpha; TIGRFAM: Succinyl-CoA ligase, alpha subunit; IMG reference gene:2504122341; PFAM: CoA binding domain; CoA-ligase; TIGRFAM: succinyl-CoA synthetase, alpha subunit YP_004255739.1 COGs: COG0045 Succinyl-CoA synthetase beta subunit; HAMAP: Succinyl-CoA synthetase, beta subunit; InterPro IPR005809:IPR013650:IPR005811; KEGG: dra:DR_1247 succinyl-CoA synthetase subunit beta; PFAM: ATP-grasp fold, succinyl-CoA synthetase-type; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: Succinyl-CoA ligase [ADP-forming] subunit beta; TIGRFAM: Succinyl-CoA synthetase, beta subunit; IMG reference gene:2504122342; PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit YP_004255740.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: dge:Dgeo_1087 peptidase M24; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: Peptidase M24; IMG reference gene:2504122343; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain YP_004255741.1 COGs: COG0797 Lipoprotein; InterPro IPR009009:IPR012997; KEGG: ddr:Deide_11721 putative lysin (LysM) and rare lipoprotein A (RlpA) domains-containing protein, precursor; PFAM: Barwin-related endoglucanase; SPTR: Putative Lysin (LysM) and rare lipoprotein A (RlpA) domains-containing protein,; TIGRFAM: Rare lipoprotein A, bacterial; IMG reference gene:2504122344; PFAM: Rare lipoprotein A (RlpA)-like double-psi beta-barrel; TIGRFAM: rare lipoprotein A YP_004255742.1 KEGG: ddr:Deide_11730 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122345 YP_004255743.1 COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537; KEGG: dra:DR_1017 rRNA methylase; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SPTR: rRNA methylase; IMG reference gene:2504122346; PFAM: SpoU rRNA Methylase family YP_004255744.1 COGs: COG4828 membrane protein; InterPro IPR012427; KEGG: dra:DR_1328 hypothetical protein; PFAM: Protein of unknown function DUF1622; SPTR: Putative uncharacterized protein; IMG reference gene:2504122347; PFAM: Protein of unknown function (DUF1622) YP_004255745.1 COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: ddr:Deide_10300 putative 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 3-hydroxyisobutyrate dehydrogenase; SPTR: Putative 3-hydroxyisobutyrate dehydrogenase; IMG reference gene:2504122348; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase YP_004255746.1 COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: dra:DR_0500 hypothetical protein; PFAM: DegV; SPTR: DegV domain-containing protein DR_0500; TIGRFAM: DegV; IMG reference gene:2504122349; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family YP_004255747.1 KEGG: tra:Trad_1395 N-acetyl-gamma-glutamyl-phosphate reductase; SPTR:N-acetyl-gamma-glutamyl-phosphate/N-acetyl- gamma-aminoadipyl- phosphate reductase 2; IMG reference gene:2504122350 YP_004255748.1 COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; InterPro IPR004365:IPR004364; KEGG: dge:Dgeo_0796 aspartyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Aspartate--tRNA ligase; SPTR: Aspartyl-tRNA synthetase; IMG reference gene:2504122351; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain YP_004255749.1 KEGG: dra:DR_0218 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122352 YP_004255750.1 COGs: COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; InterPro IPR000760; KEGG: dge:Dgeo_0795 inositol monophosphatase; PFAM: Inositol monophosphatase; SPTR: Inositol monophosphatase; IMG reference gene:2504122353; PFAM: Inositol monophosphatase family; TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase, bacterial YP_004255751.1 COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); HAMAP: DNA-binding, RecF; InterPro IPR001238:IPR003395; KEGG: dra:DR_1089 recombination protein F; PFAM: RecF/RecN/SMC; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA-binding, RecF; IMG reference gene:2504122354; TIGRFAM: recF protein YP_004255752.1 COGs: COG5512 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives; InterPro IPR007922; KEGG: dge:Dgeo_1621 hypothetical protein; PFAM: Protein of unknown function DUF721/UPF0232; SPTR: Zn-finger containing protein; IMG reference gene:2504122355; PFAM: Protein of unknown function (DUF721) YP_004255753.1 COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453:IPR020817; KEGG: dge:Dgeo_0596 molybdopterin binding domain-containing protein; PFAM: Molybdopterin binding; SMART: Molybdopterin binding; SPTR: Molybdopterin binding domain; TIGRFAM: Molybdenum cofactor synthesis; IMG reference gene:2504122356; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain YP_004255754.1 KEGG: ddr:Deide_14280 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122357 YP_004255755.1 COGs: COG0785 Cytochrome c biogenesis protein; InterPro IPR003834; KEGG: dge:Dgeo_1241 cytochrome c biogenesis protein, transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane domain; SPTR: Cytochrome c biogenesis protein, transmembrane region; IMG reference gene:2504122358; PFAM: Cytochrome C biogenesis protein transmembrane region YP_004255756.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ddr:Deide_08340 putative ABC transporter, ATP-binding component; PFAM: ABC transporter-like; PRIAM: Heme-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative ABC transporter, ATP-binding component; IMG reference gene:2504122359; PFAM: ABC transporter YP_004255757.1 COGs: COG2386 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR003544; KEGG: dge:Dgeo_1243 cytochrome c-type biogenesis protein CcmB; PFAM: Cytochrome c-type biogenesis protein CcmB; SPTR: Cytochrome c-type biogenesis protein CcmB; IMG reference gene:2504122360; PFAM: CcmB protein; TIGRFAM: heme exporter protein CcmB YP_004255758.1 COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterPro IPR000534:IPR012280:IPR005986; KEGG: dge:Dgeo_1782 aspartate-semialdehyde dehydrogenase, USG-1 related; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD-binding; PRIAM: Aspartate-semialdehyde dehydrogenase; SMART: Semialdehyde dehydrogenase, NAD-binding; SPTR: Aspartate-semialdehyde dehydrogenase, USG-1 related; TIGRFAM: Aspartate-semialdehyde dehydrogenase, bacterial; IMG reference gene:2504122361; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) YP_004255759.1 COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR018111:IPR003714; KEGG: dge:Dgeo_1272 PhoH-like protein protein; PFAM: PhoH-like protein; K Homology, type 1, subgroup; SPTR: PhoH-like protein, ATPase; IMG reference gene:2504122362; PFAM: PhoH-like protein YP_004255760.1 COGs: COG0605 Superoxide dismutase; InterPro IPR019831:IPR019832; KEGG: dra:DR_1279 Mn family superoxide dismutase; PFAM: Manganese/iron superoxide dismutase, C-terminal; Manganese/iron superoxide dismutase, N-terminal; PRIAM: Superoxide dismutase; SPTR: Superoxide dismutase [Mn]; IMG reference gene:2504122363; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain YP_004255761.1 KEGG: dge:Dgeo_0879 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122364; PFAM: Protein of unknown function (DUF3208) YP_004255762.1 KEGG: dra:DR_2157 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122365 YP_004255763.1 KEGG: xca:xccb100_3169 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2504122366 YP_004255764.1 COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: ddr:Deide_12480 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; IMG reference gene:2504122367; PFAM: Delta-aminolevulinic acid dehydratase YP_004255765.1 COGs: COG2453 protein-tyrosine phosphatase; InterPro IPR000242:IPR003595; KEGG: dge:Dgeo_0883 dual specificity protein phosphatase; PFAM: Protein-tyrosine phosphatase, receptor/non-receptor type; SMART: Protein-tyrosine phosphatase, catalytic; SPTR: Dual specificity protein phosphatase; IMG reference gene:2504122368; PFAM: Dual specificity phosphatase, catalytic domain YP_004255766.1 COGs: COG2329 Uncharacterized protein involved in biosynthesis of extracellular polysaccharides; InterPro IPR007138; KEGG: dge:Dgeo_0884 antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: Antibiotic biosynthesis monooxygenase; IMG reference gene:2504122369; PFAM: Antibiotic biosynthesis monooxygenase YP_004255767.1 COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR004489; KEGG: dge:Dgeo_0886 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; IMG reference gene:2504122370; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_004255768.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011281:IPR014006; KEGG: ddr:Deide_12450 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: Putative Succinate dehydrogenase, flavoprotein subunit; TIGRFAM: Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; IMG reference gene:2504122371; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup YP_004255769.1 COGs: COG2142 Succinate dehydrogenase hydrophobic anchor subunit; InterPro IPR000701; KEGG: dge:Dgeo_0888 succinate dehydrogenase, cytochrome b subunit; PFAM: Succinate dehydrogenase/Fumarate reductase, transmembrane subunit; SPTR: Succinate dehydrogenase, cytochrome b subunit; IMG reference gene:2504122372; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein YP_004255770.1 InterPro IPR000701:IPR014314; KEGG: dge:Dgeo_0889 succinate dehydrogenase, cytochrome b subunit; PFAM: Succinate dehydrogenase/Fumarate reductase, transmembrane subunit; SPTR: Succinate dehydrogenase, cytochrome b subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; IMG reference gene:2504122373; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit YP_004255771.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; HAMAP: tRNA-specific 2-thiouridylase; InterPro IPR004506; KEGG: ddr:Deide_12840 tRNA-specific 2-thiouridylase MnmA; PFAM: tRNA-specific 2-thiouridylase; SPTR: tRNA-specific 2-thiouridylase mnmA; TIGRFAM: tRNA-specific 2-thiouridylase; IMG reference gene:2504122374; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004255772.1 InterPro IPR001647; KEGG: dge:Dgeo_0788 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504122375; PFAM: Bacterial regulatory proteins, tetR family YP_004255773.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149:IPR020843:IPR014188; KEGG: dge:Dgeo_1229 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; SMART: Polyketide synthase, enoylreductase; SPTR: Alcohol dehydrogenase, zinc-binding; TIGRFAM: Quinone oxidoreductase putative, YhdH/YhfP; IMG reference gene:2504122376; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative quinone oxidoreductase, YhdH/YhfP family YP_004255774.1 COGs: COG1098 RNA binding protein (contains ribosomal protein S1 domain); InterPro IPR003029:IPR022967; KEGG: dge:Dgeo_0674 RNA binding S1; PFAM: Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: Putative uncharacterized protein; IMG reference gene:2504122377; PFAM: S1 RNA binding domain YP_004255775.1 COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; HAMAP: 3-phosphoshikimate 1-carboxyvinyltransferase; InterPro IPR006264:IPR001986; KEGG: dra:DR_1096 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: Enolpyruvate transferase domain; PRIAM: 3-phosphoshikimate 1-carboxyvinyltransferase; SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; IMG reference gene:2504122378; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase YP_004255776.1 KEGG: mxa:MXAN_6633 hypothetical protein; SPTR: Putative membrane protein; IMG reference gene:2504122379 YP_004255777.1 COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: dra:DR_1252 hypothetical protein; PFAM: Saccharopine dehydrogenase / Homospermidine synthase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122380; PFAM: Saccharopine dehydrogenase YP_004255778.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: dge:Dgeo_0943 hypothetical protein; PFAM: Aminotransferase, class I/classII; SPTR: Aminotransferase MocR family; IMG reference gene:2504122381; PFAM: Aminotransferase class I and II YP_004255779.1 KEGG: dge:Dgeo_0480 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122382 YP_004255780.1 InterPro IPR011637; KEGG: ddr:Deide_17380 hypothetical protein; PFAM: Uncharacterised protein family YphA; SPTR: Putative uncharacterized protein; IMG reference gene:2504122383; PFAM: DoxX YP_004255781.1 COGs: COG3012 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0225; InterPro IPR023006:IPR004027; KEGG: dra:DR_0483 hypothetical protein; PFAM: SEC-C motif; SPTR: UPF0225 protein DR_0483; manually curated; IMG reference gene:2504122384; PFAM: SEC-C motif YP_004255782.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058:IPR004527; KEGG: msv:Mesil_1516 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; PRIAM: Glutamate--tRNA ligase; SPTR: Glutamyl-tRNA synthetase; TIGRFAM: Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial; IMG reference gene:2504122385; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004255783.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: ddr:Deide_14230 putative polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Putative Polyprenyl synthetase; IMG reference gene:2504122386; PFAM: Polyprenyl synthetase YP_004255784.1 InterPro IPR016047; KEGG: dge:Dgeo_1482 peptidase M23B; PFAM: Peptidase M23; SPTR: Peptidase M23B; IMG reference gene:2504122387; PFAM: Peptidase family M23 YP_004255785.1 COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: dge:Dgeo_1481 hypothetical protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Cell division FtsX protein; IMG reference gene:2504122388; PFAM: Predicted permease YP_004255786.1 COGs: COG2884 ATPase involved in cell division; InterPro IPR003439:IPR003593:IPR005286; KEGG: ddr:Deide_10690 putative cell division ATP-binding protein FtsE; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative Cell division ATP-binding protein ftsE; TIGRFAM: Cell division ATP-binding protein FtsE; IMG reference gene:2504122389; PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE YP_004255787.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: ddr:Deide_10700 putative C-terminal processing peptidase; PFAM: Peptidase S41; PDZ/DHR/GLGF; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: Putative C-terminal processing peptidase; TIGRFAM: Peptidase S41A, C-terminal peptidase; manually curated; IMG reference gene:2504122390; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004255788.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: svo:SVI_2773 sodium:dicarboxylate symporter family protein; PFAM: Sodium:dicarboxylate symporter; SPTR: Sodium:dicarboxylate symporter family protein; IMG reference gene:2504122391; PFAM: Sodium:dicarboxylate symporter family YP_004255789.1 InterPro IPR001279; KEGG: dge:Dgeo_1029 beta-lactamase-like protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Beta-lactamase-like protein; IMG reference gene:2504122392; PFAM: Metallo-beta-lactamase superfamily YP_004255790.1 KEGG: dra:DR_1786 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122393 YP_004255791.1 KEGG: ddr:Deide_06690 hypothetical protein; SPTR: Protein containing PATAN domain; IMG reference gene:2504122394 YP_004255792.1 InterPro IPR011701; KEGG: ddr:Deide_07480 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative uncharacterized protein; IMG reference gene:2504122395; PFAM: Major Facilitator Superfamily YP_004255793.1 InterPro IPR000086; KEGG: dra:DR_0149 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2504122396; PFAM: NUDIX domain YP_004255794.1 COGs: COG0525 Valyl-tRNA synthetase; HAMAP: Valyl-tRNA synthetase; InterPro IPR002303:IPR002300:IPR013155:IPR019499; KEGG: dra:DR_0148 valyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA-binding arm; PRIAM: Valine--tRNA ligase; SPTR: Valyl-tRNA synthetase; TIGRFAM: Valyl-tRNA synthetase; IMG reference gene:2504122397; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase YP_004255795.1 InterPro IPR012867; KEGG: ddr:Deide_2p02170 hypothetical protein; putative membrane protein; PFAM: Protein of unknown function DUF1648; SPTR: Putative uncharacterized protein; IMG reference gene:2504122398; PFAM: Protein of unknown function (DUF1648) YP_004255796.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: dge:Dgeo_1314 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family; IMG reference gene:2504122399; PFAM: Bacterial regulatory protein, arsR family YP_004255797.1 COGs: COG4315 conserved hypothetical protein; InterPro IPR005297; KEGG: aav:Aave_3375 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122400; PFAM: Secreted repeat of unknown function YP_004255798.1 COGs: COG0645 kinase; KEGG: dra:DR_2467 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122401; PFAM: Zeta toxin YP_004255799.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; HAMAP: Lysidine-tRNA(Ile) synthetase; InterProIPR012094:IPR011063:IPR002125:IPR012796:IPR 012795; KEGG: dra:DR_1207 cell cycle protein MesJ, putative/cytosine deaminase-related protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase; CMP/dCMP deaminase, zinc-binding; SMART: Lysidine-tRNA(Ile) synthetase, C-terminal; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: Lysidine-tRNA(Ile) synthetase, N-terminal; Lysidine-tRNA(Ile) synthetase, C-terminal; IMG reference gene:2504122402; PFAM: TilS substrate C-terminal domain; PP-loop family; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain YP_004255800.1 COGs: COG1522 Transcriptional regulators; InterPro IPR019887:IPR019888; KEGG: dra:DR_0200 Lpr/AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type, C-terminal; SMART: Transcription regulator AsnC-type; SPTR: Transcriptional regulator, Lrp/AsnC family; IMG reference gene:2504122403; PFAM: Bacterial regulatory protein, arsR family; AsnC family YP_004255801.1 COGs: COG3871 Uncharacterized stress protein (general stress protein 26); InterPro IPR011576; KEGG: dge:Dgeo_0891 pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase-related, FMN-binding, Gsp26; IMG reference gene:2504122404; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004255802.1 InterPro IPR004843; KEGG: dra:DR_0761 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122405; PFAM: Calcineurin-like phosphoesterase YP_004255803.1 COGs: COG0344 membrane protein; HAMAP: Glycerol-3-phosphate acyltransferase, bacteria; InterPro IPR003811; KEGG: dra:DR_2021 membrane protein; PFAM: Glycerol-3-phosphate acyltransferase, bacteria; SPTR: Glycerol-3-phosphate acyltransferase 1; TIGRFAM: Glycerol-3-phosphate acyltransferase, bacteria; IMG reference gene:2504122406; PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase YP_004255804.1 COGs: COG2206 HD-GYP domain; InterProIPR013655:IPR006674:IPR001610:IPR003607:IPR 000014:IPR006675; KEGG: mrb:Mrub_1050 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; PAS fold-3; SMART: Metal-dependent phosphohydrolase, HD domain; PAC motif; SPTR: Metal dependent phosphohydrolase; TIGRFAM: PAS; Uncharacterised protein family HDIG; IMG reference gene:2504122407; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box YP_004255805.1 COGs: COG0266 Formamidopyrimidine-DNA glycosylase; HAMAP: Formamidopyrimidine-DNA glycosylase; InterProIPR020629:IPR012319:IPR015886:IPR010663:IPR 000191; KEGG: dge:Dgeo_0442 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, catalytic domain; DNA glycosylase/AP lyase, H2TH DNA-binding; Zinc finger, DNA glycosylase/AP lyase/isoleucyl tRNA synthetase; PRIAM: DNA-formamidopyrimidine glycosylase; SMART: DNA glycosylase/AP lyase, catalytic domain; SPTR: Formamidopyrimidine-DNA glycosylase; TIGRFAM: DNA glycosylase/AP lyase; IMG reference gene:2504122408; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; Zinc finger found in FPG and IleRS; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg) YP_004255806.1 COGs: COG0259 Pyridoxamine-phosphate oxidase; HAMAP: Pyridoxamine 5'-phosphate oxidase; InterPro IPR000659:IPR011576:IPR019576; KEGG: dra:DR_0495 pyridoxamine 5-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal; PRIAM: Pyridoxal 5'-phosphate synthase; SPTR: Pyridoxine/pyridoxamine 5'-phosphate oxidase; TIGRFAM: Pyridoxamine 5'-phosphate oxidase; IMG reference gene:2504122409; PFAM: Pyridoxamine 5'-phosphate oxidase; Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; TIGRFAM: pyridoxamine-phosphate oxidase YP_004255807.1 KEGG: dge:Dgeo_0444 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122410; PFAM: NfeD-like YP_004255808.1 COGs: COG2268 conserved hypothetical protein; InterPro IPR001107; KEGG: dge:Dgeo_0445 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Flotillin family protein; IMG reference gene:2504122411; PFAM: SPFH domain / Band 7 family YP_004255809.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016215; KEGG: ske:Sked_27610 flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; SPTR: Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; TIGRFAM: Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A; IMG reference gene:2504122413; PFAM: Luciferase-like monooxygenase; TIGRFAM: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family YP_004255810.1 InterPro IPR001647; KEGG: ske:Sked_27620 transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Putative transcriptional regulator; IMG reference gene:2504122414; PFAM: Bacterial regulatory proteins, tetR family YP_004255811.1 COGs: COG2085 dinucleotide-binding protein; InterPro IPR004455; KEGG: pfo:Pfl01_2766 NADP oxidoreductase, coenzyme F420-dependent; PFAM: NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative exported protein; IMG reference gene:2504122415; PFAM: NADP oxidoreductase coenzyme F420-dependent YP_004255812.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048:IPR019949; KEGG: mlu:Mlut_13410 flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like, subgroup; SPTR: Luciferase family oxidoreductase, group 1; TIGRFAM: Luciferase family oxidoreductase, group 1; IMG reference gene:2504122416; PFAM: Luciferase-like monooxygenase; TIGRFAM: luciferase family oxidoreductase, group 1 YP_004255813.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR004638; KEGG: hau:Haur_1459 EmrB/QacA family drug resistance transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: Drug resistance transporter EmrB/QacA subfamily; IMG reference gene:2504122417; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_004255814.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046:IPR020047:IPR015361:IPR001098:IPR 002421:IPR008918:IPR018320; KEGG: dge:Dgeo_1666 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, alpha-helical arch, N-terminal; 5'-3' exonuclease, SAM-fold domain; Taq polymerase, thermostable, exonuclease region; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease, N-terminal; Helix-hairpin-helix motif, class 2; DNA-directed DNA polymerase, family A, palm domain; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase 1; IMG reference gene:2504122418; PFAM: Taq polymerase, exonuclease; 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase family A; TIGRFAM: DNA polymerase I YP_004255815.1 IMG reference gene:2504122419 YP_004255816.1 KEGG: ami:Amir_3713 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122420 YP_004255817.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120; KEGG: ddr:Deide_09700 putative amidase; PFAM: Amidase; SPTR: Putative Amidase; IMG reference gene:2504122424; PFAM: Amidase YP_004255818.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003959:IPR003593:IPR012763; KEGG: dge:Dgeo_2135 DNA polymerase III, subunits gamma and tau; PFAM: ATPase, AAA-type, core; PRIAM: DNA-directed DNA polymerase; SMART: ATPase, AAA+ type, core; SPTR: DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunit gamma/ tau; IMG reference gene:2504122425; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau YP_004255819.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR015358:IPR010211; KEGG: rer:RER_43780 MerR family transcriptional regulator; PFAM: Transcription regulator MerR, DNA binding; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Putative MerR family transcriptional regulator; TIGRFAM: Redox-sensitive transcriptional activator SoxR; IMG reference gene:2504122426; PFAM: MerR family regulatory protein; MerR, DNA binding; TIGRFAM: redox-sensitive transcriptional activator SoxR YP_004255820.1 KEGG: dra:DR_0767 short chain dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122427 YP_004255821.1 IMG reference gene:2504122428 YP_004255822.1 IMG reference gene:2504122429 YP_004255823.1 InterPro IPR004360; KEGG: ara:Arad_3537 lactoylglutathione lyase protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase; IMG reference gene:2504122430; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004255824.1 COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: ara:Arad_8446 ornithine cyclodeaminase protein; PFAM: Ornithine cyclodeaminase/mu-crystallin; SPTR: Ornithine cyclodeaminase protein; manually curated; IMG reference gene:2504122431; PFAM: Ornithine cyclodeaminase/mu-crystallin family YP_004255825.1 COGs: COG1514 2'-5' RNA ligase; InterPro IPR014051:IPR004175; KEGG: dra:DR_2339 2'-5' RNA ligase, putative; PFAM: Phosphoesterase, HXTX; SPTR: 2`-5` RNA ligase, putative; TIGRFAM: 2',5' RNA ligase; IMG reference gene:2504122432; PFAM: 2',5' RNA ligase family; TIGRFAM: 2'-5' RNA ligase YP_004255826.1 COGs: COG0468 RecA/RadA recombinase; HAMAP: DNA recombination and repair protein RecA; InterPro IPR013765:IPR003593; KEGG: dra:DR_2340 recombinase A; PFAM: DNA recombination and repair protein RecA; SMART: ATPase, AAA+ type, core; SPTR: Protein recA; TIGRFAM: DNA recombination and repair protein RecA; IMG reference gene:2504122433; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_004255827.1 COGs: COG4252 transmembrane sensor domain; InterPro IPR007890; KEGG: dra:DR_1633 GGDEF family protein; PFAM: CHASE2; SPTR: GGDEF family protein; IMG reference gene:2504122434; PFAM: CHASE2 domain YP_004255828.1 InterPro IPR006860; KEGG: dra:DR_1634 hypothetical protein; PFAM: FecR protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122435; PFAM: FecR protein YP_004255829.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: dra:DR_1635 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein, EF-3 family; IMG reference gene:2504122436; PFAM: ABC transporter YP_004255830.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: dge:Dgeo_1269 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver sensor signal transduction histidine kinase; IMG reference gene:2504122437; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain YP_004255831.1 COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR013767:IPR013656:IPR013655:IPR003661:IPR 003594:IPR000014:IPR001610; KEGG: dra:DR_1174 sensory box sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold-4; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif; SPTR: Sensory box sensor histidine kinase; TIGRFAM: PAS; IMG reference gene:2504122438; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004255832.1 COGs: COG0169 Shikimate 5-dehydrogenase; HAMAP: Shikimate, quinate/shikimate dehydrogenase; InterPro IPR022893:IPR013708:IPR006151; KEGG: ddr:Deide_10760 putative shikimate dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: Shikimate dehydrogenase; IMG reference gene:2504122439; PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase YP_004255833.1 COGs: COG0585 conserved hypothetical protein; HAMAP: Pseudouridine synthase, TruD; InterPro IPR001656; KEGG: ddr:Deide_14290 putative tRNA pseudouridine synthase D (tRNA-uridine isomerase D)(tRNA pseudouridylate synthase D); PFAM: Pseudouridine synthase, TruD; SPTR: tRNA pseudouridine synthase D; TIGRFAM: Pseudouridine synthase, TruD; IMG reference gene:2504122440; PFAM: tRNA pseudouridine synthase D (TruD); TIGRFAM: tRNA pseudouridine synthase, TruD family YP_004255834.1 KEGG: dge:Dgeo_0593 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122441; PFAM: Protein of unknown function (DUF3293) YP_004255835.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR006145:IPR000748; KEGG: dge:Dgeo_0763 pseudouridine synthase, Rsu; PFAM: RNA-binding S4; Pseudouridine synthase, RsuA and RluB/C/D/E/F; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; IMG reference gene:2504122443; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase YP_004255836.1 KEGG: dge:Dgeo_0762 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122444 YP_004255837.1 KEGG: dra:DR_2592 hypothetical protein; SPTR: Hypothetical secreted protein; IMG reference gene:2504122445 YP_004255838.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: ddr:Deide_04430 putative (uracil-5)-methyltransferase; PFAM: (Uracil-5)-methyltransferase; SPTR: Putative (Uracil-5)-methyltransferase; IMG reference gene:2504122446; PFAM: tRNA (Uracil-5-)-methyltransferase YP_004255839.1 KEGG: syd:Syncc9605_0170 putative glycosyl transferase, group 1; SPTR: Putative glycosyl transferase, group 1; IMG reference gene:2504122447 YP_004255840.1 COGs: COG5403 conserved hypothetical protein; KEGG: dra:DR_0201 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122448; PFAM: Bacterial protein of unknown function (DUF937) YP_004255841.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478; KEGG: ddr:Deide_10420 putative trypsin-like serine protease, precursor; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: Putative trypsin-like serine protease,; IMG reference gene:2504122449; PFAM: Trypsin YP_004255842.1 COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: dra:DR_A0267 hypothetical protein; PFAM: Formylmethanofuran dehydrogenase, subunit E domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122450; PFAM: Prokaryotic dksA/traR C4-type zinc finger; FmdE, Molybdenum formylmethanofuran dehydrogenase operon YP_004255843.1 InterPro IPR005184; KEGG: dra:DR_1940 hypothetical protein; PFAM: Domain of unknown function DUF306, Meta/HslJ; SPTR: Putative uncharacterized protein; IMG reference gene:2504122451; PFAM: META domain YP_004255844.1 InterPro IPR011701; KEGG: dge:Dgeo_1542 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504122452; PFAM: Major Facilitator Superfamily YP_004255845.1 COGs: COG2306 conserved hypothetical protein; KEGG: ddr:Deide_16350 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122454; PFAM: Protein of unknown function (DUF402) YP_004255846.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR002376:IPR004607; KEGG: dge:Dgeo_1546 formyl transferase-like protein; PFAM: Formyl transferase, N-terminal; PRIAM: Phosphoribosylglycinamide formyltransferase; SPTR: Formyl transferase-like protein; TIGRFAM: Phosphoribosylglycinamide formyltransferase; IMG reference gene:2504122455; PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_004255847.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650; KEGG: dra:DR_2025 ArgE/DapE/Acy1 family protein; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: Beta-Ala-His dipeptidase; SPTR: ArgE/DapE/Acy1 family protein; IMG reference gene:2504122456; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain YP_004255848.1 COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: dra:DR_A0059 hypothetical protein; PFAM: Transcription regulator PadR N-terminal-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504122457; PFAM: Transcriptional regulator PadR-like family YP_004255849.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: dge:Dgeo_0565 alpha/beta hydrolase fold; PFAM: Alpha/beta hydrolase fold-1; SPTR: Alpha/beta hydrolase fold; IMG reference gene:2504122458; PFAM: alpha/beta hydrolase fold YP_004255850.1 COGs: COG1432 conserved hypothetical protein; InterPro IPR021139; KEGG: dra:DR_1578 hypothetical protein; PFAM: Domain of unknown function DUF88; SPTR: Putative uncharacterized protein; IMG reference gene:2504122459; PFAM: Protein of unknown function DUF88 YP_004255851.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); HAMAP: Queuosine biosynthesis protein; InterPro IPR003699; KEGG: dge:Dgeo_0946 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; TIGRFAM: Queuosine biosynthesis protein; IMG reference gene:2504122460; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004255852.1 InterPro IPR014051; KEGG: dge:Dgeo_1904 hypothetical protein; PFAM: Phosphoesterase, HXTX; SPTR: 2'-5' phosphodiesterase of the 2H superfamily; IMG reference gene:2504122461 YP_004255853.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dge:Dgeo_1003 nitroreductase; PFAM: Nitroreductase-like; SPTR: NAD(P)H-flavin oxidoreductase, nitroreductase family; IMG reference gene:2504122462; PFAM: Nitroreductase family YP_004255854.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: dge:Dgeo_0966 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal; PRIAM: NADPH dehydrogenase; SPTR: NADH:flavin oxidoreductase/NADH oxidase; IMG reference gene:2504122463; PFAM: NADH:flavin oxidoreductase / NADH oxidase family YP_004255855.1 InterPro IPR007272; KEGG: clo:HMPREF0868_1588 YeeE/YedE family protein; PFAM: Domain of unknown function DUF395, YeeE/YedE; SPTR: YeeE/YedE family integral membrane protein; IMG reference gene:2504122464; PFAM: YeeE/YedE family (DUF395) YP_004255856.1 COGs: COG1092 SAM-dependent methyltransferase; KEGG: dra:DR_1694 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122465; PFAM: Methyltransferase small domain YP_004255857.1 KEGG: npu:Npun_F3111 zinc/iron permease; SPTR: Zinc/iron permease; IMG reference gene:2504122466 YP_004255858.1 InterPro IPR000620; KEGG: dge:Dgeo_0313 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Permease of the drug/metabolite transporter (DMT) superfamily; IMG reference gene:2504122467; PFAM: EamA-like transporter family YP_004255859.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120; KEGG: mrb:Mrub_2929 amidase; PFAM: Amidase; PRIAM: Amidase; SPTR: Amidase; IMG reference gene:2504122468; PFAM: Amidase YP_004255860.1 COGs: COG1066 ATP-dependent serine protease; InterPro IPR003593:IPR004504; KEGG: dra:DR_1105 DNA repair protein RadA; SMART: ATPase, AAA+ type, core; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; IMG reference gene:2504122469; PFAM: KaiC; TIGRFAM: DNA repair protein RadA YP_004255861.1 KEGG: dge:Dgeo_1213 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122470; PFAM: Uncharacterized protein conserved in bacteria (DUF2087) YP_004255862.1 InterPro IPR018660; KEGG: dra:DR_1818 hypothetical protein; PFAM: Protein of unknown function DUF2091, periplasmic; SPTR: Putative uncharacterized protein; IMG reference gene:2504122471; PFAM: Membrane-bound lysozyme-inhibitor of c-type lysozyme YP_004255863.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455:IPR000304; KEGG: dge:Dgeo_0841 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: Pyrroline-5-carboxylate reductase; IMG reference gene:2504122472; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_004255864.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR004176:IPR003959:IPR013093:IPR003593; KEGG: ddr:Deide_12680 putative ATP-dependent Clp protease, ATP-binding subunit ClpC; PFAM: ATPase, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Putative ATP-dependent Clp protease, ATP-binding subunit ClpC; IMG reference gene:2504122473; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA) YP_004255865.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR018833:IPR002529; KEGG: dra:DR_1609 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase-related protein; PFAM: Fumarylacetoacetase, C-terminal-like; Domain of unknown function DUF2437; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase-related protein; IMG reference gene:2504122474; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family YP_004255866.1 COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: dge:Dgeo_1219 aminotransferase class-III; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Aminotransferase class-III; IMG reference gene:2504122475; PFAM: Aminotransferase class-III YP_004255867.1 KEGG: ddr:Deide_11270 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122476 YP_004255868.1 COGs: COG0788 Formyltetrahydrofolate hydrolase; InterPro IPR002912:IPR002376:IPR004810; KEGG: mcu:HMPREF0573_11522 formyltetrahydrofolate deformylase; PFAM: Formyl transferase, N-terminal; Amino acid-binding ACT; PRIAM: Formyltetrahydrofolate deformylase; SPTR: Formyltetrahydrofolate deformylase; TIGRFAM: Formyltetrahydrofolate deformylase; manually curated; IMG reference gene:2504122477; PFAM: ACT domain; Formyl transferase; TIGRFAM: formyltetrahydrofolate deformylase YP_004255869.1 IMG reference gene:2504122478 YP_004255870.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: dra:DR_2466 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: Putative uncharacterized protein; IMG reference gene:2504122479; PFAM: NIF3 (NGG1p interacting factor 3) YP_004255871.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR011545:IPR001650:IPR018982:IPR002121:IPR 014001:IPR006293:IPR004589; KEGG: ddr:Deide_11320 putative ATP-dependent DNA helicase; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; SMART: RQC domain; Helicase, C-terminal; DEAD-like helicase, N-terminal; Helicase/RNase D C-terminal, HRDC domain; SPTR: Putative ATP-dependent DNA helicase; TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type; IMG reference gene:2504122480; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family YP_004255872.1 COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: dge:Dgeo_2524 DeoR family transcriptional regulator; PFAM: Sugar-binding domain, putative; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504122481; PFAM: Putative sugar-binding domain YP_004255873.1 COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425:IPR012269; KEGG: dge:Dgeo_2523 MIP family channel protein; PFAM: Major intrinsic protein; SPTR: Glycerol uptake facilitator GlpF, MIP/aquaporin family; TIGRFAM: Aquaporin; IMG reference gene:2504122482; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_004255874.1 COGs: COG0554 Glycerol kinase; HAMAP: Glycerol kinase; InterPro IPR005999:IPR018484:IPR018485; KEGG: dge:Dgeo_2522 glycerol kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; PRIAM: Glycerol kinase; SPTR: Glycerol kinase; TIGRFAM: Glycerol kinase; IMG reference gene:2504122483; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004255875.1 COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076; KEGG: dra:DR_1019 glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: Glycerol-3-phosphate dehydrogenase; IMG reference gene:2504122484; PFAM: FAD dependent oxidoreductase YP_004255876.1 KEGG: tra:Trad_2558 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122485 YP_004255877.1 COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006158:IPR005129:IPR006099:IPR006098; KEGG: rso:RSc0237 putative methylmalonyl-CoA mutase protein; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; Cobalamin (vitamin B12)-binding; ArgK protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Putative methylmalonyl-coa mutase protein; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; IMG reference gene:2504122486; PFAM: ArgK protein; Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain YP_004255878.1 COGs: COG1190 Lysyl-tRNA synthetase (class II); HAMAP: Lysyl-tRNA synthetase, class II; InterPro IPR002313:IPR004365:IPR004364; KEGG: ddr:Deide_05030 lysyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class II; IMG reference gene:2504122487; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial YP_004255879.1 COGs: COG0782 Transcription elongation factor; InterPro IPR022691:IPR001437; KEGG: ddr:Deide_05020 putative transcription elongation factor; PFAM: Transcription elongation factor, GreA/GreB, C-terminal; Transcription elongation factor, GreA/GreB, N-terminal; SPTR: Putative transcription elongation factor; IMG reference gene:2504122488; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term YP_004255880.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: dge:Dgeo_0736 acyl-CoA dehydrogenase-like protein; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; PRIAM: Acyl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase-like protein; IMG reference gene:2504122489; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004255881.1 COGs: COG1092 SAM-dependent methyltransferase; KEGG: dra:DR_1834 hypothetical protein; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122490; PFAM: S-adenosylmethionine-dependent methyltransferase YP_004255882.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; HAMAP: Phospho-N-acetylmuramoyl-pentapeptide transferase; InterPro IPR003524:IPR018480:IPR000715; KEGG: ddr:Deide_14680 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR:Phospho-N-acetylmuramoyl-pentapeptide-transfer ase; TIGRFAM: Phospho-N-acetylmuramoyl-pentapeptide transferase; IMG reference gene:2504122491; PFAM: Glycosyl transferase family 4 YP_004255883.1 COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: ddr:Deide_09250 putative FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Putative FAD dependent oxidoreductase; IMG reference gene:2504122492; PFAM: FAD dependent oxidoreductase YP_004255884.1 COGs: COG4121 conserved hypothetical protein; InterPro IPR008471; KEGG: ddr:Deide_09260 conserved hypothetical protein, precursor; PFAM: Domain of unknown function DUF752; SPTR: Putative uncharacterized protein; IMG reference gene:2504122493; PFAM: Protein of unknown function (DUF752) YP_004255885.1 InterPro IPR019060; KEGG: dge:Dgeo_1455 hypothetical protein; PFAM: Domain of unknown function DUF2382, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504122494; PFAM: Domain of unknown function (DUF2382) YP_004255886.1 COGs: COG3861 conserved hypothetical protein; InterPro IPR007903:IPR019060:IPR011756; KEGG: dra:DR_1314 hypothetical protein; PFAM: Domain of unknown function DUF2382, C-terminal; PRC-barrel; SPTR: Uncharacterized protein DR_1314; TIGRFAM: Conserved hypothetical protein CHP02271, C-terminal; IMG reference gene:2504122495; PFAM: Domain of unknown function (DUF2382); PRC-barrel domain; TIGRFAM: conserved domain YP_004255887.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: dra:DR_0261 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; manually curated; IMG reference gene:2504122496; PFAM: NUDIX domain YP_004255888.1 COGs: COG4143 ABC-type thiamine transport system periplasmic component; InterPro IPR006059:IPR005948; KEGG: dge:Dgeo_1933 ABC transporter periplasmic-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: ABC-type thiamine transport system, periplasmic component; TIGRFAM: Thiamine ABC transporter periplasmic binding protein; IMG reference gene:2504122497; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily YP_004255889.1 COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: dge:Dgeo_1934 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type thiamine transport system, permease component; two domain fusion; IMG reference gene:2504122498; PFAM: Binding-protein-dependent transport system inner membrane component YP_004255890.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: dge:Dgeo_1938 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type polyamine transport system, ATPase component; IMG reference gene:2504122499; PFAM: ABC transporter YP_004255891.1 COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371:IPR006282; KEGG: dra:DR_0552 hypothetical protein; PFAM: Thiamin pyrophosphokinase, catalytic domain; SPTR: Putative uncharacterized protein; TIGRFAM: Thiamin pyrophosphokinase; IMG reference gene:2504122500; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase YP_004255892.1 COGs: COG4329 membrane protein; InterPro IPR018719; KEGG: ddr:Deide_3p02510 hypothetical protein; PFAM: Protein of unknown function DUF2243, membrane; SPTR: Putative uncharacterized protein; IMG reference gene:2504122501; PFAM: Predicted membrane protein (DUF2243) YP_004255893.1 COGs: COG3336 membrane protein; InterPro IPR019108; KEGG: ddr:Deide_3p02500 hypothetical protein; PFAM: Cytochrome c oxidase caa3-type, assembly factor CtaG-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504122502; PFAM: Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) YP_004255894.1 KEGG: dge:Dgeo_1941 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122503 YP_004255895.1 KEGG: dge:Dgeo_0932 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122504 YP_004255896.1 COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: ddr:Deide_21730 hypothetical protein; PFAM: Peptidase S66, LD-carboxypeptidase A; SPTR: Putative uncharacterized protein; IMG reference gene:2504122505; PFAM: LD-carboxypeptidase YP_004255897.1 COGs: COG2717 membrane protein; InterPro IPR013130; KEGG: ddr:Deide_20370 putative sulfite oxidase subunit YedZ; PFAM: Flavoprotein transmembrane component; SPTR: Sulfoxide reductase heme-binding subunit yedZ; IMG reference gene:2504122506; PFAM: Ferric reductase like transmembrane component YP_004255898.1 COGs: COG2041 Sulfite oxidase; InterPro IPR000572; KEGG: ddr:Deide_20380 putative sulfite oxidase subunit YedY; PFAM: Oxidoreductase, molybdopterin-binding domain; SPTR: Putative molybdopterin binding protein; putative oxidoreductase; IMG reference gene:2504122507; PFAM: Oxidoreductase molybdopterin binding domain YP_004255899.1 InterPro IPR000835; KEGG: ddr:Deide_01540 putative transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Putative Transcriptional regulator, MarR family; IMG reference gene:2504122508 YP_004255900.1 COGs: COG2124 Cytochrome P450; InterPro IPR001128; KEGG: dge:Dgeo_0143 cytochrome P450; PFAM: Cytochrome P450; SPTR: Cytochrome P450; IMG reference gene:2504122509; PFAM: Cytochrome P450 YP_004255901.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360; KEGG: nml:Namu_3901 glycoside hydrolase family 1; PFAM: Glycoside hydrolase, family 1; PRIAM: 6-phospho-beta-glucosidase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122510; PFAM: Glycosyl hydrolase family 1 YP_004255902.1 KEGG: dra:DR_A0019 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122511 YP_004255903.1 KEGG: hau:Haur_2818 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122512 YP_004255904.1 COGs: COG0216 Protein chain release factor A; HAMAP: Peptide chain release factor 1; InterPro IPR004373:IPR005139:IPR000352; KEGG: dge:Dgeo_0609 peptide chain release factor 1; PFAM: Peptide chain release factor class I/class II; Peptide chain release factor; SMART: Peptide chain release factor; SPTR: Peptide chain release factor 1; TIGRFAM: Peptide chain release factor 1; IMG reference gene:2504122513; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1 YP_004255905.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: ddr:Deide_15950 putative NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2504122514; PFAM: NUDIX domain YP_004255906.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942:IPR006145:IPR006225; KEGG: ddr:Deide_16790 putative ribosomal large subunit pseudouridine synthase D; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD; IMG reference gene:2504122515; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family YP_004255907.1 COGs: COG1628 conserved hypothetical protein; HAMAP: Protein of unknown function DUF99; InterPro IPR002802; KEGG: dra:DR_A0167 hypothetical protein; PFAM: Protein of unknown function DUF99; SPTR: UPF0215 protein DR_A0167; manually curated; IMG reference gene:2504122516; PFAM: Protein of unknown function DUF99 YP_004255908.1 COGs: COG0290 Translation initiation factor 3 (IF-3); HAMAP: Translation initiation factor 3; InterPro IPR001288:IPR019814:IPR019815; KEGG: dra:DR_2087 translation initiation factor IF-3; PFAM: Translation initiation factor 3, N-terminal; Translation initiation factor 3, C-terminal; SPTR: Translation initiation factor IF-3; TIGRFAM: Translation initiation factor 3; IMG reference gene:2504122517; PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_004255909.1 COGs: COG0718 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0133; InterPro IPR004401; KEGG: ddr:Deide_06350 hypothetical protein; PFAM: Uncharacterised protein family UPF0133; SPTR: UPF0133 protein Deide_06350; TIGRFAM: Uncharacterised protein family UPF0133; IMG reference gene:2504122518; PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: DNA-binding protein, YbaB/EbfC family YP_004255910.1 COGs: COG0353 Recombinational DNA repair protein (RecF pathway); HAMAP: RecR protein; InterPro IPR000093:IPR015967:IPR006171:IPR003583; KEGG: ddr:Deide_06340 recombination protein RecR; PFAM: Toprim domain; Zinc finger C4-type, RecR; SMART: Toprim domain; Helix-hairpin-helix DNA-binding motif, class 1; SPTR: Recombination protein recR; TIGRFAM: RecR protein; IMG reference gene:2504122519; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_004255911.1 KEGG: xac:XAC1166 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122520 YP_004255912.1 COGs: COG2865 transcriptional regulator protein; KEGG: ddr:Deide_14310 putative predicted transcriptional regulator; SPTR: Putative Predicted transcriptional regulator; IMG reference gene:2504122521 YP_004255913.1 COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: ddr:Deide_14150 putative hypoxanthine phosphoribosyltransferase (hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504122522; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_004255914.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: dra:DR_1393 phosphoglycerate mutase, putative; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1; SPTR: Phosphoglycerate mutase, putative; IMG reference gene:2504122523; PFAM: Phosphoglycerate mutase family YP_004255915.1 COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728:IPR010918:IPR004733; KEGG: dge:Dgeo_1616 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504122524; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase YP_004255916.1 COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR004879; KEGG: dge:Dgeo_1263 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122525; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255 YP_004255917.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015273; KEGG: dra:DR_1670 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia; Cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: Cysteine--tRNA ligase; SMART: Cysteinyl-tRNA synthetase, class Ia, DALR; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; IMG reference gene:2504122526; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase YP_004255918.1 COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814:IPR010164; KEGG: fps:FP0739 ornithine--oxo-acid transaminase; PFAM: Aminotransferase class-III; PRIAM: Ornithine aminotransferase; SPTR: Ornithine--oxo-acid transaminase; TIGRFAM: Ornithine aminotransferase; IMG reference gene:2504122527; PFAM: Aminotransferase class-III; TIGRFAM: ornithine aminotransferase YP_004255919.1 InterPro IPR000551; KEGG: ddr:Deide_16380 putative transcriptional regulator, MerR family; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Putative Transcriptional regulator, MerR family; IMG reference gene:2504122528; PFAM: MerR family regulatory protein YP_004255920.1 KEGG: dge:Dgeo_1000 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122529 YP_004255921.1 COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); HAMAP: Ribosomal RNA adenine dimethylase; InterPro IPR011530:IPR001737:IPR020598; KEGG: dge:Dgeo_1143 dimethyladenosine transferase; PFAM: Ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase, N-terminal; SPTR: Ribosomal RNA small subunit methyltransferase A; TIGRFAM: Ribosomal RNA adenine dimethylase; IMG reference gene:2504122530; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_004255922.1 COGs: COG1048 Aconitase A; InterPro IPR001030:IPR000573:IPR006249; KEGG: ddr:Deide_07920 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; PRIAM: Aconitate hydratase; SPTR: Putative aconitate hydratase (Citrate hydro-lyase) (Aconitase); TIGRFAM: Aconitase/iron regulatory protein 2; IMG reference gene:2504122531; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1 YP_004255923.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: ddr:Deide_16800 putative DEAD-box ATP-dependent RNA helicase 3; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Putative DEAD-box ATP-dependent RNA helicase 3; IMG reference gene:2504122532; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004255924.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: dge:Dgeo_1142 PfkB; PFAM: Carbohydrate/purine kinase; SPTR: Fructokinase RbsK; IMG reference gene:2504122533; PFAM: pfkB family carbohydrate kinase YP_004255925.1 COGs: COG3597 Uncharacterized protein/domain associated with GTPase; KEGG: ddr:Deide_16420 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122534; PFAM: Domain of unknown function (DUF697) YP_004255926.1 COGs: COG0205 6-phosphofructokinase; HAMAP: Phosphofructokinase; InterPro IPR022953:IPR000023:IPR012828; KEGG: dge:Dgeo_1637 6-phosphofructokinase; PFAM: Phosphofructokinase domain; PRIAM: 6-phosphofructokinase; SPTR: 6-phosphofructokinase; TIGRFAM: 6-phosphofructokinase; IMG reference gene:2504122535; PFAM: Phosphofructokinase; TIGRFAM: 6-phosphofructokinase YP_004255927.1 COGs: COG0313 methyltransferase; HAMAP: Ribosomal RNA small subunit methyltransferase I; InterPro IPR000878:IPR008189; KEGG: dra:DR_0636 hypothetical protein; PFAM: Tetrapyrrole methylase; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0011; IMG reference gene:2504122536; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family YP_004255928.1 KEGG: ddr:Deide_14630 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122537 YP_004255929.1 KEGG: dge:Dgeo_1640 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122538 YP_004255930.1 KEGG: dge:Dgeo_0935 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122539 YP_004255931.1 COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: dge:Dgeo_1696 4-hydroxybenzoyl-CoA thioesterase; PFAM: Thioesterase superfamily; SPTR: 4-hydroxybenzoyl-CoA thioesterase; TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; IMG reference gene:2504122540; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004255932.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: ddr:Deide_15430 putative NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: Putative NUDIX hydrolase; IMG reference gene:2504122541; PFAM: NUDIX domain YP_004255933.1 InterPro IPR007055:IPR018392:IPR014004:IPR002482; KEGG: dra:DR_0888 hypothetical protein; PFAM: Peptidoglycan-binding lysin domain; Transport-associated; SMART: Peptidoglycan-binding Lysin subgroup; Transport-associated and nodulation domain, bacteria; SPTR: Uncharacterized protein DR_0888; IMG reference gene:2504122542; PFAM: Putative phospholipid-binding domain; LysM domain YP_004255934.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: dge:Dgeo_1706 periplasmic sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2504122543; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004255935.1 KEGG: ddr:Deide_15380 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122544 YP_004255936.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dra:DR_1558 DNA-binding response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: DNA-binding response regulator; IMG reference gene:2504122545; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004255937.1 InterPro IPR005632; KEGG: dge:Dgeo_0715 outer membrane chaperone Skp (OmpH); PFAM: Outer membrane chaperone Skp (OmpH); SMART: Outer membrane chaperone Skp (OmpH); SPTR: Outer membrane chaperone Skp (OmpH); IMG reference gene:2504122546; PFAM: Outer membrane protein (OmpH-like) YP_004255938.1 COGs: COG0599 gamma-carboxymuconolactone decarboxylase subunit; InterPro IPR003779; KEGG: dra:DR_0973 gamma-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; SPTR: Gamma-carboxymuconolactone decarboxylase; IMG reference gene:2504122547; PFAM: Carboxymuconolactone decarboxylase family YP_004255939.1 COGs: COG1193 Mismatch repair ATPase (MutS family); HAMAP: DNA mismatch repair protein MutS, type 2; InterPro IPR005747:IPR000432:IPR002625:IPR007696; KEGG: dge:Dgeo_0899 MutS2 family protein; PFAM: Smr protein/MutS2 C-terminal; DNA mismatch repair protein MutS, C-terminal; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; Smr protein/MutS2 C-terminal; SPTR: MutS2 protein; TIGRFAM: DNA mismatch repair protein MutS, type 2; IMG reference gene:2504122548; PFAM: MutS domain V; Smr domain; TIGRFAM: MutS2 family protein YP_004255940.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: dge:Dgeo_0968 Crp/FNR family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2504122549; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_004255941.1 COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460; KEGG: dge:Dgeo_1895 peptidoglycan glycosyltransferase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504122550; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase YP_004255942.1 COGs: COG1970 Large-conductance mechanosensitive channel; InterPro IPR001185; KEGG: dra:DR_2422 large conductance mechanosensitive channel; PFAM: Large-conductance mechanosensitive channel; SPTR: Large conductance mechanosensitive channel; TIGRFAM: Large-conductance mechanosensitive channel; manually curated; IMG reference gene:2504122551; PFAM: Large-conductance mechanosensitive channel, MscL; TIGRFAM: large conductance mechanosensitive channel protein YP_004255943.1 COGs: COG1625 Fe-S oxidoreductase related to NifB/MoaA family; InterPro IPR001478:IPR007549; KEGG: ddr:Deide_02230 hypothetical protein; PFAM: Domain of unknown function DUF512; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Putative uncharacterized protein; IMG reference gene:2504122552; PFAM: Protein of unknown function (DUF512); PDZ domain (Also known as DHR or GLGF); TIGRFAM: putative FeS-containing Cyanobacterial-specific oxidoreductase YP_004255944.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: dra:DR_0016 hypothetical protein; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2504122553; PFAM: Sir2 family YP_004255945.1 InterPro IPR013105:IPR001440:IPR019734; KEGG: dge:Dgeo_0632 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2; IMG reference gene:2504122554 YP_004255946.1 InterPro IPR007730; KEGG: ddr:Deide_14021 putative sporulation related domain-containing protein; PFAM: Sporulation-related domain; SPTR: Putative Sporulation related domain-containing protein; IMG reference gene:2504122555; PFAM: Sporulation related domain YP_004255947.1 COGs: COG2344 AT-rich DNA-binding protein; HAMAP: Transcriptional repressor, redox-sensing, Rex; InterPro IPR022876:IPR009718:IPR003781; KEGG: ddr:Deide_14030 redox-sensing transcriptional repressor REX; PFAM: CoA-binding; Rex DNA-binding, C-terminal; SMART: CoA-binding; SPTR: Redox-sensing transcriptional repressor rex; IMG reference gene:2504122556; PFAM: CoA binding domain; Putative DNA-binding protein N-terminus YP_004255948.1 KEGG: dge:Dgeo_0629 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122557 YP_004255949.1 KEGG: dge:Dgeo_0628 hypothetical protein; SPTR: PKD domain protein, secreted; IMG reference gene:2504122558 YP_004255950.1 COGs: COG1806 conserved hypothetical protein; HAMAP: Protein of unknown function DUF299, phosphotransferase, predicted; InterPro IPR005177; KEGG: dge:Dgeo_0622 hypothetical protein; PFAM: Protein of unknown function DUF299, phosphotransferase, predicted; SPTR: Putative phosphotransferase Dgeo_0622; manually curated; IMG reference gene:2504122559; PFAM: Domain of unknown function (DUF299) YP_004255951.1 COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR000121:IPR006319; KEGG: dra:DR_1727 phosphoenolpyruvate synthase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme; PRIAM: Pyruvate, water dikinase; SPTR: Phosphoenolpyruvate synthase; TIGRFAM: Phosphoenolpyruvate synthase; IMG reference gene:2504122560; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: phosphoenolpyruvate synthase YP_004255952.1 InterPro IPR002696; KEGG: ddr:Deide_08465 hypothetical protein; PFAM: Protein of unknown function DUF37; SPTR: Putative uncharacterized protein; IMG reference gene:2504122562 YP_004255953.1 COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: dra:DR_0211 hypothetical protein; PFAM: Mechanosensitive ion channel MscS; SPTR: Putative uncharacterized protein; IMG reference gene:2504122563; PFAM: Mechanosensitive ion channel YP_004255954.1 InterPro IPR000782; KEGG: dra:DR_0399 osteoblast specific factor 2-related protein; PFAM: FAS1 domain; SPTR: Osteoblast specific factor 2-related protein; IMG reference gene:2504122564; PFAM: Fasciclin domain YP_004255955.1 COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002142; KEGG: ddr:Deide_13000 putative peptidase S49, signal peptide peptidase (SPPase); PFAM: Peptidase S49; SPTR: Putative peptidase S49, Signal peptide peptidase (SPPase); IMG reference gene:2504122565; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type YP_004255956.1 COGs: COG2137 conserved hypothetical protein; HAMAP: Regulatory protein RecX; InterPro IPR003783; KEGG: dra:DR_1310 recombination regulator RecX; PFAM: Regulatory protein RecX; SPTR: Regulatory protein recX; IMG reference gene:2504122567; PFAM: RecX family YP_004255957.1 HAMAP: Ribosomal protein S20; InterPro IPR002583; KEGG: dge:Dgeo_1432 30S ribosomal protein S20; PFAM: Ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: Ribosomal protein S20; IMG reference gene:2504122568; PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_004255958.1 COGs: COG0813 Purine-nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase; InterPro IPR004402:IPR000845; KEGG: dra:DR_2166 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase domain; PRIAM: Purine-nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase; TIGRFAM: Purine nucleoside phosphorylase; IMG reference gene:2504122569; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD) YP_004255959.1 KEGG: dhd:Dhaf_0838 transcriptional regulator, PadR-like family; SPTR: Putative uncharacterized protein; IMG reference gene:2504122570 YP_004255960.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: dge:Dgeo_1498 NusB/RsmB/TIM44; PFAM: NusB/RsmB/TIM44; Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: rRNA methyltransferase, sun family protein; IMG reference gene:2504122571; PFAM: NOL1/NOP2/sun family; NusB family YP_004255961.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dge:Dgeo_1499 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504122572; PFAM: Major Facilitator Superfamily YP_004255962.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; HAMAP: Deoxyxylulose-5-phosphate synthase; InterPro IPR005477:IPR005475:IPR005476; KEGG: dge:Dgeo_0994 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: Deoxyxylulose-5-phosphate synthase; IMG reference gene:2504122573; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004255963.1 KEGG: dge:Dgeo_0995 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122574 YP_004255964.1 COGs: COG1842 Phage shock protein A (IM30) suppresses sigma54-dependent transcription; InterPro IPR007157; KEGG: dge:Dgeo_0996 phage shock protein A, PspA; PFAM: PspA/IM30; SPTR: Phage shock protein A, PspA; IMG reference gene:2504122575; PFAM: PspA/IM30 family YP_004255965.1 KEGG: ddr:Deide_09460 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504122576 YP_004255966.1 KEGG: dge:Dgeo_1646 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122577 YP_004255967.1 KEGG: dge:Dgeo_1645 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122578 YP_004255968.1 KEGG: dge:Dgeo_1644 putative Ig; SPTR: Cell ssuface protein containing Ig-like domain; IMG reference gene:2504122579 YP_004255969.1 COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: dge:Dgeo_1290 phosphoesterase, RecJ-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Phosphoesterase, RecJ-like protein; IMG reference gene:2504122580; PFAM: DHH family; DHHA1 domain YP_004255970.1 KEGG: hsl:OE5132F putative phosphate transport protein; SPTR: Sodium-dependent phosphate transporter; IMG reference gene:2504122581 YP_004255971.1 COGs: COG2367 Beta-lactamase class A; KEGG: dra:DR_1985 beta-lactamase, putative; SPTR: Beta-lactamase, putative; IMG reference gene:2504122582 YP_004255972.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: ddr:Deide_12050 putative cysteine-rich domain-containing Fe-S oxidoreductase; putative membrane protein; PFAM: Cysteine-rich domain; 4Fe-4S binding domain; SPTR: Putative Cysteine-rich domain-containing Fe-S oxidoreductase; putative membrane protein; IMG reference gene:2504122583; PFAM: Cysteine-rich domain YP_004255973.1 KEGG: dra:DR_2002 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122584 YP_004255974.1 KEGG: dmo:Dmoj_GI18047 GI18047 gene product from transcript GI18047-RA; SPTR: GI18047; IMG reference gene:2504122585 YP_004255975.1 COGs: COG0342 Preprotein translocase subunit SecD; InterProIPR022646:IPR022813:IPR005791:IPR022645:IPR 005665; KEGG: dge:Dgeo_1239 bifunctional preprotein translocase subunit SecD/SecF; PFAM: Preprotein translocase, SecD/SecF/SecDF; SecD/SecF/SecDF export membrane protein, GG motif, N-terminal; SPTR: Protein-export membrane protein SecD; TIGRFAM: SecD export membrane protein; SecD/SecF/SecDF export membrane protein, bacteria; SecF protein; IMG reference gene:2504122586; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF YP_004255976.1 KEGG: dge:Dgeo_0743 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122587 YP_004255977.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372:IPR005790; KEGG: dge:Dgeo_0745 DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; IMG reference gene:2504122588; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_004255978.1 KEGG: ddr:Deide_16940 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122589 YP_004255979.1 COGs: COG0754 Glutathionylspermidine synthase; InterPro IPR005494; KEGG: ddr:Deide_16950 putative glutathionylspermidine synthase; PFAM: Glutathionylspermidine synthase; SPTR: Putative glutathionylspermidine synthase; IMG reference gene:2504122590; PFAM: Glutathionylspermidine synthase YP_004255980.1 InterPro IPR005821; KEGG: ddr:Deide_16960 putative ion transport protein; putative membrane protein; PFAM: Ion transport; SPTR: Putative Ion transport protein; putative membrane protein; IMG reference gene:2504122591; PFAM: Ion transport protein YP_004255981.1 InterPro IPR000620; KEGG: sti:Sthe_2637 protein of unknown function DUF6 transmembrane; PFAM: Drug/metabolite transporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504122592; PFAM: EamA-like transporter family YP_004255982.1 COGs: COG0433 ATPase; KEGG: ddr:Deide_16770 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122594 YP_004255983.1 COGs: COG4242 Cyanophycinase and related exopeptidase; InterPro IPR005320; KEGG: gym:GYMC10_4368 peptidase S51 dipeptidase E; PFAM: Peptidase S51; SPTR: Peptidase S51 dipeptidase E; IMG reference gene:2504122595; PFAM: Peptidase family S51 YP_004255984.1 COGs: COG2380 conserved hypothetical protein; InterPro IPR018977; KEGG: dra:DR_0836 hypothetical protein; PFAM: NurA domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122596 YP_004255985.1 COGs: COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase alpha subunit; InterPro IPR004165:IPR012792; KEGG: dge:Dgeo_0808 3-oxoacid CoA-transferase, subunit A; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SMART: Coenzyme A transferase; SPTR: 3-oxoacid CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, subunit A; IMG reference gene:2504122597; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, A subunit YP_004255986.1 COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR004165:IPR012791; KEGG: dra:DR_A0067 CoA transferase, subunit B; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SMART: Coenzyme A transferase; SPTR: CoA transferase, subunit B; TIGRFAM: 3-oxoacid CoA-transferase, subunit B; IMG reference gene:2504122598; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit YP_004255987.1 KEGG: dra:DR_1541 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122599 YP_004255988.1 COGs: COG2124 Cytochrome P450; InterPro IPR001128; KEGG: dra:DR_2473 cytochrome P450; PFAM: Cytochrome P450; SPTR: Cytochrome P450; IMG reference gene:2504122600; PFAM: Cytochrome P450 YP_004255989.1 KEGG: cbr:CBG24580 Hypothetical protein CBG24580; SPTR: Putative uncharacterized protein; IMG reference gene:2504122601 YP_004255990.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: ddr:Deide_14880 putative propionyl-CoA carboxylase (PCCase); PFAM: Carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: Putative Propionyl-CoA carboxylase (PCCase); IMG reference gene:2504122602; PFAM: Carboxyl transferase domain YP_004255991.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: dra:DR_1544 acyl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase; IMG reference gene:2504122603; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004255992.1 KEGG: vex:VEA_004504 putative hemolysin; SPTR: Putative hemolysin; IMG reference gene:2504122604 YP_004255993.1 COGs: COG1392 Phosphate transport regulator (distant homolog of PhoU); InterPro IPR018445; KEGG: dra:DR_0924 hypothetical protein; PFAM: Putitive phosphate transport regulator; SPTR: Putative uncharacterized protein; IMG reference gene:2504122605; PFAM: Protein of unknown function DUF47; TIGRFAM: TIGR00153 family protein YP_004255994.1 COGs: COG0306 Phosphate/sulphate permease; InterPro IPR001204; KEGG: dra:DR_0925 low-affinity inorganic phosphate transporter, putative; PFAM: Phosphate transporter; SPTR: Low-affinity inorganic phosphate transporter, putative; IMG reference gene:2504122606; PFAM: Phosphate transporter family YP_004255995.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: ddr:Deide_1p01450 hypothetical protein; PFAM: Uncharacterised protein family UPF0118; SPTR: Putative uncharacterized protein; IMG reference gene:2504122607; PFAM: Domain of unknown function DUF20 YP_004255996.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; HAMAP: UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR005762:IPR013221:IPR004101; KEGG: dra:DR_2496 UDP-N-acetylmuramoylalanine--D-glutamiate ligase; PFAM: Mur ligase, central; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine-D-glutamate ligase; IMG reference gene:2504122608; PFAM: Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004255997.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: dge:Dgeo_0486 cell cycle protein; PFAM: Cell cycle protein; SPTR: Cell cycle protein; IMG reference gene:2504122609; PFAM: Cell cycle protein YP_004255998.1 COGs: COG2206 HD-GYP domain; InterPro IPR006674; KEGG: dge:Dgeo_1298 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504122610; PFAM: HD domain YP_004255999.1 InterPro IPR005358; KEGG: ddr:Deide_11910 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein; IMG reference gene:2504122611; PFAM: Uncharacterised protein family (UPF0153) YP_004256000.1 COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450:IPR000357; KEGG: ddr:Deide_16490 putative electron transport protein YjeS; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; HEAT; SPTR: Putative electron transport protein yjeS; IMG reference gene:2504122612; PFAM: HEAT repeat; Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative YP_004256001.1 InterPro IPR013990; KEGG: ddr:Deide_09710 putative desiccation-associated late embryogenesis abundant (Lea) protein, precursor; water stress and hypersensitive response (WHy) domain protein, precursor; SMART: Water stress and hypersensitive response domain; SPTR: Putative desiccation-associated late embryogenesis abundant (Lea) protein,; Water Stress and Hypersensitive response (WHy) domain protein,; IMG reference gene:2504122613; PFAM: Late embryogenesis abundant protein YP_004256002.1 KEGG: dra:DR_1371 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122614 YP_004256003.1 COGs: COG2834 Outer membrane lipoprotein-sorting protein; KEGG: dge:Dgeo_1553 hypothetical protein; SPTR: Outer membrane lipoprotein-sorting protein, LolA family; IMG reference gene:2504122615 YP_004256004.1 COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR019468; KEGG: ddr:Deide_16710 putative adenylosuccinate lyase (adenylosuccinase); PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; SPTR: Putative adenylosuccinate lyase (Adenylosuccinase); TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504122616; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase YP_004256005.1 COGs: COG0143 Methionyl-tRNA synthetase; HAMAP: Methionyl-tRNA synthetase, class Ia; InterPro IPR014758:IPR004495:IPR015413:IPR002547; KEGG: dra:DR_1433 methionyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); tRNA-binding domain; PRIAM: Methionine--tRNA ligase; SPTR: Methionyl-tRNA synthetase; TIGRFAM: Methionyl-tRNA synthetase, class Ia; Methionyl-tRNA synthetase, class Ia, beta subunit, C-terminal; IMG reference gene:2504122617; PFAM: tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase YP_004256006.1 COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: dra:DR_2303 chloramphenicol acetyltransferase; PFAM: Chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase; IMG reference gene:2504122618; PFAM: Chloramphenicol acetyltransferase YP_004256007.1 COGs: COG1388 FOG: LysM repeat; InterPro IPR018392:IPR002482; KEGG: dge:Dgeo_1694 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidoglycan-binding LysM domain-containing protein; IMG reference gene:2504122619; PFAM: LysM domain; Predicted periplasmic protein (DUF2233) YP_004256008.1 KEGG: dge:Dgeo_1532 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122620 YP_004256009.1 KEGG: dge:Dgeo_0547 von Willebrand factor, type A; SPTR: von Willebrand factor, type A; IMG reference gene:2504122621 YP_004256010.1 COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR003594:IPR013506:IPR006171:IPR002288:IPR 001241; KEGG: dge:Dgeo_0546 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA topoisomerase, type IIA, subunit B, domain 2; ATPase-like, ATP-binding domain; Toprim domain; DNA topoisomerase, type IIA, subunit B, C-terminal; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit B/N-terminal; ATPase-like, ATP-binding domain; SPTR: DNA topoisomerase (ATP-hydrolyzing); IMG reference gene:2504122622; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit YP_004256011.1 COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: dge:Dgeo_2139 BioY protein; PFAM: BioY protein; SPTR: BioY protein; IMG reference gene:2504122623; PFAM: BioY family YP_004256012.1 COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004409:IPR004408:IPR004143:IPR003142; KEGG: dge:Dgeo_2140 bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal; SPTR: Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; Biotin operon repressor, helix-turn-helix domain; IMG reference gene:2504122624; PFAM: Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: BirA biotin operon repressor domain; birA, biotin-[acetyl-CoA-carboxylase] ligase region YP_004256013.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: dge:Dgeo_2141 ferric uptake regulator family protein; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; IMG reference gene:2504122625; PFAM: Ferric uptake regulator family YP_004256014.1 KEGG: dra:DR_2342 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122626 YP_004256015.1 COGs: COG1403 Restriction endonuclease; InterPro IPR002711:IPR003615; KEGG: dra:DR_2409 hypothetical protein; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: Putative uncharacterized protein; IMG reference gene:2504122627; PFAM: HNH endonuclease YP_004256016.1 KEGG: ecb:100146412 similar to Coiled-coil domain-containing protein 9; SPTR: Uncharacterized protein; IMG reference gene:2504122628 YP_004256017.1 COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: tra:Trad_2364 patatin; PFAM: Patatin/Phospholipase A2-related; SPTR: Patatin; IMG reference gene:2504122629; PFAM: Patatin-like phospholipase YP_004256018.1 COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR006256:IPR000089:IPR004167:IPR001078; KEGG: dra:DR_0256 pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase E2 component; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; PRIAM: Dihydrolipoyllysine-residue acetyltransferase; SPTR: Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase E2 component; TIGRFAM: Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex; IMG reference gene:2504122630; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form YP_004256019.1 COGs: COG2609 Pyruvate dehydrogenase complex dehydrogenase (E1) component; InterPro IPR004660:IPR005474; KEGG: ddr:Deide_03160 pyruvate dehydrogenase subunit E1; PFAM: Transketolase, N-terminal; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: Pyruvate dehydrogenase E1 component; TIGRFAM: 2-oxo-acid dehydrogenase E1 component homodimeric type; IMG reference gene:2504122631; PFAM: Transketolase, thiamine diphosphate binding domain; TIGRFAM: pyruvate dehydrogenase E1 component, homodimeric type YP_004256020.1 COGs: COG4282 Protein involved in beta-1 3-glucan synthesis; InterPro IPR018958; KEGG: ddr:Deide_22450 hypothetical protein; PFAM: Cell wall assembly/cell proliferation coordinating protein, KNR4-like; SMART: Cell wall assembly/cell proliferation coordinating protein, KNR4-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504122633; PFAM: SMI1 / KNR4 family YP_004256021.1 KEGG: cob:COB47_1565 hypothetical protein; SPTR: Alpha amylase, catalytic region; IMG reference gene:2504122634 YP_004256022.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: dra:DR_0615 LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504122635; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004256023.1 KEGG: msv:Mesil_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122636 YP_004256024.1 COGs: COG0167 Dihydroorotate dehydrogenase; HAMAP: Dihydroorotate dehydrogenase, class 2; InterPro IPR005719:IPR012135; KEGG: dge:Dgeo_0500 dihydroorotate dehydrogenase 2; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; PRIAM: Dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase; TIGRFAM: Dihydroorotate dehydrogenase, class 2; IMG reference gene:2504122637; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2 YP_004256025.1 KEGG: dra:DR_1331 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122638 YP_004256026.1 COGs: COG0780 Enzyme related to GTP cyclohydrolase I; HAMAP: Nitrile oxidoreductase, NADPH-dependent, QueF; InterPro IPR016856:IPR020602; KEGG: ddr:Deide_19030 putative GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: PreQ(1) synthase; SPTR: Putative GTP cyclohydrolase I; TIGRFAM: Nitrile oxidoreductase, NADPH-dependent, QueF; IMG reference gene:2504122639; PFAM: GTP cyclohydrolase I; TIGRFAM: 7-cyano-7-deazaguanine reductase YP_004256027.1 COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; KEGG: ddr:Deide_00320 putative 6-pyruvoyl tetrahydrobiopterin synthase, (PTP synthase); SPTR: Putative 6-pyruvoyl tetrahydrobiopterin synthase, (PTP synthase); IMG reference gene:2504122640; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein YP_004256028.1 COGs: COG0602 Organic radical activating protein; InterPro IPR007197; KEGG: ddr:Deide_00330 putative organic radical activating enzyme; PFAM: Radical SAM; SPTR: Putative Organic radical activating enzyme; IMG reference gene:2504122641; PFAM: Radical SAM superfamily YP_004256029.1 COGs: COG0603 PP-loop superfamily ATPase; InterPro IPR018317; KEGG: ddr:Deide_00340 putative queuosine biosynthesis protein; PFAM: Queuosine synthesis; SPTR: 7-cyano-7-deazaguanine synthase; TIGRFAM: Queuosine synthesis; IMG reference gene:2504122642; PFAM: ExsB; TIGRFAM: queuosine biosynthesis protein QueC YP_004256030.1 KEGG: scb:SCAB_71621 hypothetical protein; SPTR: PknB-group protein kinase; IMG reference gene:2504122643 YP_004256031.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; HAMAP: tRNA (guanine-N1-)-methyltransferase, bacteria; InterPro IPR002649:IPR016009; KEGG: dge:Dgeo_1486 tRNA (guanine-N(1)-)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1-)-methyltransferase, bacteria; IMG reference gene:2504122644; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_004256032.1 COGs: COG0806 RimM protein required for 16S rRNA processing; HAMAP: 16S rRNA processing protein RimM; InterPro IPR011961:IPR002676:IPR007903; KEGG: dge:Dgeo_1485 16S rRNA-processing protein RimM; PFAM: RimM protein; PRC-barrel; SPTR: Ribosome maturation factor rimM; TIGRFAM: 16S rRNA processing protein RimM; IMG reference gene:2504122645; PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_004256033.1 COGs: COG1837 RNA-binding protein (contains KH domain); KEGG: dra:DR_2009 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122646 YP_004256034.1 COGs: COG0130 Pseudouridine synthase; HAMAP: tRNA pseudouridine synthase II, TruB; InterPro IPR014780:IPR002501; KEGG: ddr:Deide_08630 tRNA pseudouridine synthase B; PFAM: Pseudouridine synthase II; SPTR: tRNA pseudouridine synthase B; TIGRFAM: tRNA pseudouridine synthase II, TruB; IMG reference gene:2504122647; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase YP_004256035.1 KEGG: ddr:Deide_14670 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504122648 YP_004256036.1 InterPro IPR001647; KEGG: ddr:Deide_12960 putative transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Putative Transcriptional regulator, TetR family; IMG reference gene:2504122649; PFAM: Bacterial regulatory proteins, tetR family YP_004256037.1 KEGG: gdj:Gdia_3066 alpha/beta hydrolase fold; SPTR: Putative poly-beta-hydroxybutyrate polymerase; IMG reference gene:2504122650 YP_004256038.1 KEGG: aor:AO090010000275 hypothetical protein; SPTR: Adenylyl cyclase-associated protein; IMG reference gene:2504122651 YP_004256039.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543:IPR018541:IPR003593; KEGG: dge:Dgeo_1654 cell divisionFtsK/SpoIIIE; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase FtsK gamma; SMART: DNA translocase FtsK gamma; ATPase, AAA+ type, core; SPTR: Cell division protein FtsK; IMG reference gene:2504122652; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family YP_004256040.1 COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; KEGG: dra:DR_0402 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122653 YP_004256041.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: dge:Dgeo_0867 cation diffusion facilitator family transporter; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; IMG reference gene:2504122654; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004256042.1 InterPro IPR004360; KEGG: dge:Dgeo_1981 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/Dioxygenase family protein; IMG reference gene:2504122655 YP_004256043.1 HAMAP: Ribosomal protein L35, non-mitochondrial; InterPro IPR001706:IPR021137; KEGG: ddr:Deide_05910 50S ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: Ribosomal protein L35, non-mitochondrial; IMG reference gene:2504122656; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_004256044.1 COGs: COG0292 Ribosomal protein L20; HAMAP: Ribosomal protein L20; InterPro IPR005813; KEGG: dge:Dgeo_0574 50S ribosomal protein L20; PFAM: Ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: Ribosomal protein L20; IMG reference gene:2504122657; PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_004256045.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ddr:Deide_06630 putative polyphosphate--glucose phosphotransferase; PFAM: ROK; PRIAM: Polyphosphate--glucose phosphotransferase; SPTR: Putative polyphosphate--glucose phosphotransferase; IMG reference gene:2504122658; PFAM: ROK family YP_004256046.1 COGs: COG3142 Uncharacterized protein involved in copper resistance; InterPro IPR005627; KEGG: ccs:CCNA_02445 copper homeostasis protein CutC; PFAM: CutC; SPTR: Copper homeostasis protein CutC; manually curated; IMG reference gene:2504122659; PFAM: CutC family YP_004256047.1 COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dge:Dgeo_0576 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase; IMG reference gene:2504122660; PFAM: Amidohydrolase family YP_004256048.1 COGs: COG2217 Cation transport ATPase; InterProIPR006404:IPR006416:IPR001757:IPR008250:IPR 005834; KEGG: dra:DR_1440 cation-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504122661; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004256049.1 KEGG: dra:DR_1439 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122662; PFAM: Cytochrome c YP_004256050.1 KEGG: ddr:Deide_07900 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122663 YP_004256051.1 InterPro IPR013105:IPR011717:IPR001440:IPR019734; KEGG: dge:Dgeo_0829 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-4; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_2; IMG reference gene:2504122664 YP_004256052.1 KEGG: dge:Dgeo_0875 hypothetical protein; SPTR: Uncharacterized secreted protein containing TPR-like repeats; IMG reference gene:2504122665 YP_004256053.1 COGs: COG1490 D-Tyr-tRNAtyr deacylase; HAMAP: D-tyrosyl-tRNA(Tyr) deacylase; InterPro IPR003732; KEGG: dge:Dgeo_1517 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; IMG reference gene:2504122666; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase YP_004256054.1 InterPro IPR014995; KEGG: ddr:Deide_09750 hypothetical protein; PFAM: Protein of unknown function DUF1844; SPTR: Putative uncharacterized protein; IMG reference gene:2504122667; PFAM: Domain of unknown function (DUF1844) YP_004256055.1 COGs: COG3424 naringenin-chalcone synthase; InterPro IPR001099:IPR012328; KEGG: dra:DR_2091 chalcone synthase, putative; PFAM: Chalcone/stilbene synthase, C-terminal; Chalcone/stilbene synthase, N-terminal; PRIAM: Naringenin-chalcone synthase; SPTR: Chalcone synthase, putative; IMG reference gene:2504122668; PFAM: Chalcone and stilbene synthases, N-terminal domain; Chalcone and stilbene synthases, C-terminal domain YP_004256056.1 KEGG: ana:alr0761 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122669 YP_004256057.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR023210; KEGG: dra:DR_1890 oxidoreductase, putative; PFAM: NADP-dependent oxidoreductase domain; SPTR: Oxidoreductase, putative; IMG reference gene:2504122670; PFAM: Aldo/keto reductase family YP_004256058.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dra:DR_1271 hypothetical protein; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504122671; PFAM: Nitroreductase family YP_004256059.1 InterPro IPR011701; KEGG: gtn:GTNG_0806 putative transport protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative transport protein; IMG reference gene:2504122672; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily; TIGRFAM: metabolite-proton symporter YP_004256060.1 COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: gyc:GYMC61_1709 ornithine cyclodeaminase; PFAM: Ornithine cyclodeaminase/mu-crystallin; PRIAM: Ornithine cyclodeaminase; SPTR: Ornithine cyclodeaminase; IMG reference gene:2504122673; PFAM: Ornithine cyclodeaminase/mu-crystallin family YP_004256061.1 KEGG: dge:Dgeo_1687 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122674 YP_004256062.1 COGs: COG0105 Nucleoside diphosphate kinase; HAMAP: Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: dra:DR_2499 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504122675; PFAM: Nucleoside diphosphate kinase YP_004256063.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: dge:Dgeo_1713 hypothetical protein; PFAM: Uncharacterised protein family UPF0118; SPTR: Putative uncharacterized protein; IMG reference gene:2504122676; PFAM: Domain of unknown function DUF20 YP_004256064.1 InterPro IPR004360; KEGG: dra:DR_1695 lactoylglutathione lyase-related protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lactoylglutathione lyase-related protein; IMG reference gene:2504122677; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004256065.1 COGs: COG3253 conserved hypothetical protein; InterPro IPR010644; KEGG: dra:DR_1481 hypothetical protein; PFAM: Chlorite dismutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122678; PFAM: Chlorite dismutase YP_004256066.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: dra:DR_0986 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Extracellular solute binding protein, family 5; IMG reference gene:2504122679; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004256067.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: dge:Dgeo_0554 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Extracellular solute-binding protein, family 5; IMG reference gene:2504122680; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004256068.1 COGs: COG1281 Disulfide bond chaperones of the HSP33 family; HAMAP: Heat shock protein Hsp33 protein; InterPro IPR000397; KEGG: dra:DR_0985 hypothetical protein; PFAM: Heat shock protein Hsp33 protein; SPTR: 33 kDa chaperonin; IMG reference gene:2504122681; PFAM: Hsp33 protein YP_004256069.1 COGs: COG2056 permease; InterPro IPR018461; KEGG: prw:PsycPRwf_1978 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504122682; PFAM: Na+/H+ antiporter family YP_004256070.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; HAMAP: Orotidine 5'-phosphate decarboxylase, type 2; InterPro IPR011995:IPR001754; KEGG: dge:Dgeo_1404 orotidine 5'-phosphate decarboxylase subfamily protein; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; IMG reference gene:2504122683; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2 YP_004256071.1 KEGG: cgb:cg2308 hypothetical protein; SPTR: Putative secreted protein; IMG reference gene:2504122684 YP_004256072.1 COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765:IPR007863:IPR013578; KEGG: dge:Dgeo_1643 peptidase M16C associated; PFAM: Peptidase M16C associated; Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Peptidase M16C associated; IMG reference gene:2504122685; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_004256073.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dge:Dgeo_2149 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2504122686; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004256074.1 COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR001279:IPR011108; KEGG: ddr:Deide_19560 putative beta-lactamase-like protein; PFAM: Beta-lactamase-like; RNA-metabolising metallo-beta-lactamase; SMART: Beta-lactamase-like; SPTR: Putative beta-lactamase-like protein; IMG reference gene:2504122687; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_004256075.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108; KEGG: dra:DR_A0143 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxyacyl-CoA dehydrogenase; SPTR: 3-hydroxyacyl-CoA dehydrogenase, putative; IMG reference gene:2504122688; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004256076.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; HAMAP: Peptidase S14, ClpP; InterPro IPR001907; KEGG: dra:DR_1972 ATP-dependent Clp protease proteolytic subunit; PFAM: Peptidase S14, ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; IMG reference gene:2504122689; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_004256077.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; HAMAP: Clp protease, ATP-binding subunit ClpX; InterProIPR004487:IPR010603:IPR013093:IPR019489:IPR 003593; KEGG: dge:Dgeo_2152 ATP-dependent protease ATP-binding subunit ClpX; PFAM: ATPase, AAA-2; Zinc finger, C4-type; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpX; TIGRFAM: Clp protease, ATP-binding subunit ClpX; IMG reference gene:2504122690; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004256078.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR004815:IPR003111:IPR003959:IPR008269:IPR 003593; KEGG: dra:DR_1974 ATP-dependent protease La; PFAM: Peptidase S16, Lon C-terminal; Peptidase S16, lon N-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: Peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La; TIGRFAM: Peptidase S16, ATP-dependent protease La; IMG reference gene:2504122691; PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004256079.1 COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321:IPR001482:IPR003593; KEGG: ddr:Deide_19600 putative twitching mobility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Putative Twitching mobility protein; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504122692; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT YP_004256080.1 COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482; KEGG: dge:Dgeo_0263 type II secretion system protein E; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SPTR: Tfp pilus assembly pathway, ATPase PilB; IMG reference gene:2504122693; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein YP_004256081.1 COGs: COG2179 hydrolase of the HAD superfamily; InterPro IPR010021:IPR006549:IPR005834; KEGG: dra:DR_1965 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Putative uncharacterized protein; TIGRFAM: HAD-superfamily phosphatase, subfamily IIIA; HAD-superfamily hydrolase, subfamily IIIA; IMG reference gene:2504122694; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 YP_004256082.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: dge:Dgeo_0261 hypothetical protein; PFAM: Multi-copper polyphenol oxidoreductase, laccase; SPTR: Putative uncharacterized protein; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; IMG reference gene:2504122695; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family YP_004256083.1 COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198; KEGG: dge:Dgeo_0260 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH); SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504122696; PFAM: short chain dehydrogenase YP_004256084.1 KEGG: ddr:Deide_19650 putative isochorismatase family protein; SPTR: Putative isochorismatase family protein; IMG reference gene:2504122697 YP_004256085.1 COGs: COG1363 Cellulase M and related protein; InterPro IPR008007; KEGG: dra:DR_0946 hypothetical protein; PFAM: Peptidase M42; SPTR: Putative uncharacterized protein; IMG reference gene:2504122698; PFAM: M42 glutamyl aminopeptidase YP_004256086.1 KEGG: ddr:Deide_19055 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122699 YP_004256087.1 COGs: COG2321 metalloprotease; InterPro IPR007343; KEGG: dge:Dgeo_2115 protein of unknown function, zinc metallopeptidase putative; PFAM: Uncharacterised protein family, zinc metallopeptidase putative; SPTR: Putative uncharacterized protein; IMG reference gene:2504122700; PFAM: Putative neutral zinc metallopeptidase YP_004256088.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: dge:Dgeo_2116 acriflavin resistance protein; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; IMG reference gene:2504122701; PFAM: AcrB/AcrD/AcrF family YP_004256089.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: dge:Dgeo_2117 secretion protein HlyD; PFAM: Secretion protein HlyD; SPTR: Secretion protein HlyD; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504122702; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004256090.1 InterPro IPR001647; KEGG: dge:Dgeo_2120 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504122703; PFAM: Bacterial regulatory proteins, tetR family YP_004256091.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: ddr:Deide_19070 putative ABC transporter, ATP-binding component; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative ABC transporter, ATP-binding component; IMG reference gene:2504122704; PFAM: ABC transporter; TOBE domain YP_004256092.1 COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: ddr:Deide_19080 putative ABC transporter, permease component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Putative ABC transporter, permease component; IMG reference gene:2504122705; PFAM: Binding-protein-dependent transport system inner membrane component YP_004256093.1 COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: ddr:Deide_19090 putative ABC transporter, periplasmic component; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Putative ABC transporter, periplasmic component; IMG reference gene:2504122706; PFAM: Bacterial extracellular solute-binding protein YP_004256094.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; HAMAP: D-alanine--D-alanine ligase; InterPro IPR005905:IPR011127:IPR011095; KEGG: dra:DR_0362 D-alanyl-alanine synthetase A; PFAM: D-alanine--D-alanine ligase, C-terminal; D-alanine--D-alanine ligase, N-terminal; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine--D-alanine ligase; IMG reference gene:2504122707; PFAM: D-ala D-ala ligase C-terminus; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_004256095.1 COGs: COG5316 conserved hypothetical protein; KEGG: ddr:Deide_11101 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504122708 YP_004256096.1 COGs: COG5316 conserved hypothetical protein; KEGG: dge:Dgeo_1339 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122709 YP_004256097.1 InterPro IPR008523; KEGG: rsq:Rsph17025_0175 hypothetical protein; PFAM: Protein of unknown function DUF805; SPTR: Putative uncharacterized protein; IMG reference gene:2504122710; PFAM: Protein of unknown function (DUF805) YP_004256098.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR010066:IPR003439:IPR013563:IPR003593; KEGG: dge:Dgeo_1340 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like protein; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type oligopeptide transport system, ATPase component; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; IMG reference gene:2504122711; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004256099.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR010066:IPR003439:IPR013563:IPR003593; KEGG: dge:Dgeo_1341 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like protein; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC ATPase, oligopeptide transporter; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; IMG reference gene:2504122712; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004256100.1 InterPro IPR004692; KEGG: dge:Dgeo_1345 preprotein translocase subunit SecG; PFAM: Preprotein translocase SecG subunit; SPTR: Putative uncharacterized protein; TIGRFAM: Preprotein translocase SecG subunit; IMG reference gene:2504122713; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_004256101.1 COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: dra:DR_0291 hypothetical protein; PFAM: Protein of unknown function DUF164; SPTR: Putative uncharacterized protein; IMG reference gene:2504122714; PFAM: Putative zinc ribbon domain YP_004256102.1 InterPro IPR011701; KEGG: dra:DR_0290 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative uncharacterized protein; IMG reference gene:2504122715 YP_004256103.1 COGs: COG0177 EndoIII-related endonuclease; InterPro IPR005759:IPR003265:IPR003651; KEGG: ddr:Deide_01790 putative endonuclease III; PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SPTR: Putative endonuclease III; TIGRFAM: Endonuclease III/Nth; IMG reference gene:2504122716; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; TIGRFAM: endonuclease III YP_004256104.1 KEGG: ddr:Deide_01780 hypothetical protein; SPTR: Conserved hypothetical membrane protein; IMG reference gene:2504122717 YP_004256105.1 InterPro IPR007060; KEGG: dge:Dgeo_0245 hypothetical protein; PFAM: Septum formation initiator; SPTR: Septum formation initiator, FtsB-like protein; IMG reference gene:2504122719; PFAM: Septum formation initiator YP_004256106.1 COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR006037; KEGG: dge:Dgeo_0659 TrkA-C; PFAM: Chloride channel, voltage gated; Regulator of K+ conductance, C-terminal; SPTR: Chloride channel protein, EriC; IMG reference gene:2504122720; PFAM: Voltage gated chloride channel; TrkA-C domain YP_004256107.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); HAMAP: SecA protein; InterPro IPR000185:IPR011115:IPR011130:IPR011116; KEGG: dge:Dgeo_1058 preprotein translocase subunit SecA; PFAM: SecA DEAD-like, N-terminal; SecA preprotein, cross-linking domain; SecA Wing/Scaffold; SMART: SecA DEAD-like, N-terminal; SecA preprotein, cross-linking domain; SPTR: Protein translocase subunit secA; TIGRFAM: SecA protein; IMG reference gene:2504122721; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit YP_004256108.1 COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; InterPro IPR004821:IPR004820; KEGG: dra:DR_A0273 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; PFAM: Cytidylyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: Cytidyltransferase-related; IMG reference gene:2504122722; PFAM: Cytidylyltransferase; TIGRFAM: cytidyltransferase-related domain YP_004256109.1 COGs: COG1521 Putative transcriptional regulator protein; HAMAP: Type III pantothenate kinase; InterPro IPR004619; KEGG: dge:Dgeo_1749 pantothenate kinase; PFAM: Type III pantothenate kinase; PRIAM: Pantothenate kinase; SPTR: Type III pantothenate kinase; TIGRFAM: Type III pantothenate kinase; IMG reference gene:2504122723; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III YP_004256110.1 COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; IMG reference gene:2504122724; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme YP_004256111.1 InterPro IPR011717; KEGG: eli:ELI_08600 chromosome segregation protein; SPTR: Chromosome segregation protein; IMG reference gene:2504122725 YP_004256112.1 KEGG: dra:DR_1108 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122726 YP_004256113.1 InterPro IPR003010; KEGG: dra:DR_2184 hypothetical protein; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122727 YP_004256114.1 KEGG: dra:DR_2457 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122728 YP_004256115.1 KEGG: dra:DR_2532 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122729 YP_004256116.1 KEGG: mst:Msp_1476 HdrA1; SPTR: Putative uncharacterized protein; IMG reference gene:2504122730 YP_004256117.1 KEGG: ava:Ava_0168 hypothetical protein; SPTR: 67 kDa myosin-cross-reactive antigen like; IMG reference gene:2504122731 YP_004256118.1 COGs: COG0439 Biotin carboxylase; InterPro IPR004549:IPR005481:IPR005479:IPR005482; KEGG: dge:Dgeo_0466 acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Biotin carboxylase; SMART: Biotin carboxylase, C-terminal; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2504122732; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit YP_004256119.1 COGs: COG0511 Biotin carboxyl carrier protein; InterPro IPR001249:IPR000089; KEGG: dge:Dgeo_0467 acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Biotin/lipoyl attachment; SPTR: Acetyl-CoA carboxylase, biotin carboxyl carrier protein; TIGRFAM: Acetyl-CoA biotin carboxyl carrier; IMG reference gene:2504122733; PFAM: Biotin-requiring enzyme; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_004256120.1 COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); HAMAP: Translation elongation factor P; InterPro IPR011768:IPR013185:IPR001059:IPR015365; KEGG: dge:Dgeo_0468 elongation factor P; PFAM: Elongation factor P, C-terminal; Translation elongation factor P/YeiP, central; Translation elongation factor, KOW-like; SMART: Elongation factor P, C-terminal; SPTR: Elongation factor P; TIGRFAM: Translation elongation factor P; IMG reference gene:2504122734; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P YP_004256121.1 COGs: COG1825 Ribosomal protein L25 (general stress protein Ctc); HAMAP: Ribosomal protein L25, long-form; InterPro IPR001021:IPR020055; KEGG: dge:Dgeo_0469 50S ribosomal protein L25/general stress protein Ctc; PFAM: Ribosomal protein L25, short-form; SPTR: 50S ribosomal protein L25; TIGRFAM: Ribosomal protein L25, long-form; IMG reference gene:2504122735; PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form YP_004256122.1 COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR002937; KEGG: dra:DR_1724 hypothetical protein; PFAM: Amine oxidase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122736; PFAM: Flavin containing amine oxidoreductase YP_004256123.1 COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: dra:DR_2180 hypothetical protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504122737; PFAM: Roadblock/LC7 domain YP_004256124.1 KEGG: dra:DR_2179 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122738 YP_004256125.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: dra:DR_1588 aminotransferase, class I, putative; PFAM: Aminotransferase, class I/classII; SPTR: Aminotransferase, class I, putative; IMG reference gene:2504122739; PFAM: Aminotransferase class I and II YP_004256126.1 COGs: COG3871 Uncharacterized stress protein (general stress protein 26); InterPro IPR011576; KEGG: dra:DR_1181 hypothetical protein; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122740; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004256127.1 COGs: COG1896 hydrolase of HD superfamily; InterPro IPR006674; KEGG: dra:DR_0704 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: Putative uncharacterized protein; IMG reference gene:2504122741 YP_004256128.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR011542:IPR000825; KEGG: ddr:Deide_03330 putative FeS assembly protein SufD; PFAM: SUF system FeS cluster assembly, SufBD; SPTR: Putative FeS assembly protein SufD; TIGRFAM: SUF system FeS cluster assembly, SufD; IMG reference gene:2504122742; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD YP_004256129.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231:IPR000825; KEGG: ddr:Deide_03340 hypothetical protein; PFAM: SUF system FeS cluster assembly, SufBD; SPTR: Putative uncharacterized protein; TIGRFAM: SUF system FeS cluster assembly, SufB; IMG reference gene:2504122745; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB YP_004256130.1 COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR010230:IPR003439; KEGG: dge:Dgeo_0474 FeS assembly ATPase SufC; PFAM: ABC transporter-like; SPTR: FeS assembly ATPase SufC; TIGRFAM: ATPase SufC, SUF system FeS cluster assembly; IMG reference gene:2504122746; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_004256131.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: dra:DR_0919 hypothetical protein; PFAM: Domain of unknown function DUF58; SPTR: Putative uncharacterized protein; IMG reference gene:2504122747; PFAM: Protein of unknown function DUF58 YP_004256132.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR011703:IPR003593; KEGG: dra:DR_0918 MoxR-related protein; PFAM: ATPase, AAA-3; SMART: ATPase, AAA+ type, core; SPTR: MoxR-related protein; IMG reference gene:2504122748; PFAM: ATPase family associated with various cellular activities (AAA) YP_004256133.1 KEGG: ddr:Deide_14371 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122749 YP_004256134.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR003736:IPR006683; KEGG: dra:DR_A0198 hypothetical protein; PFAM: Thioesterase superfamily; SPTR: Putative uncharacterized protein; TIGRFAM: Phenylacetic acid degradation-related protein; IMG reference gene:2504122750; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_004256135.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284:IPR012760:IPR009042:IPR007627:IPR 007624:IPR007630; KEGG: dge:Dgeo_0476 RNA polymerase, sigma 28 subunit; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD, C-terminal; RNA polymerase sigma-70; IMG reference gene:2504122751; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain YP_004256136.1 COGs: COG2813 16S RNA G1207 methylase RsmC; InterPro IPR007848; KEGG: dge:Dgeo_1622 rRNA (guanine-N(2)-)-methyltransferase; PFAM: Methyltransferase small; SPTR: rRNA (Guanine-N(2)-)-methyltransferase; IMG reference gene:2504122752; PFAM: Methyltransferase small domain YP_004256137.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dra:DR_0267 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504122753; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004256138.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dra:DR_0267 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504122754; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004256139.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR022644:IPR022643; KEGG: kse:Ksed_00760 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, N-terminal; Orn/DAP/Arg decarboxylase 2, C-terminal; PRIAM: Diaminopimelate decarboxylase; SPTR: Diaminopimelate decarboxylase; IMG reference gene:2504122755; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_004256140.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; HAMAP: LL-diaminopimelate aminotransferase; InterPro IPR019942:IPR004839; KEGG: kse:Ksed_00770 LL-diaminopimelate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: LL-diaminopimelate aminotransferase; SPTR: LL-diaminopimelate aminotransferase; TIGRFAM: LL-diaminopimelate aminotransferase, plant-related; IMG reference gene:2504122756; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase YP_004256141.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; HAMAP: Dihydrodipicolinate synthase; InterPro IPR005263:IPR002220; KEGG: kse:Ksed_00780 dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: Dihydrodipicolinate synthase subfamily; IMG reference gene:2504122757; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase YP_004256142.1 COGs: COG0289 Dihydrodipicolinate reductase; HAMAP: Dihydrodipicolinate reductase, bacterial/plant; InterPro IPR011770:IPR000846:IPR022663; KEGG: sta:STHERM_c08680 dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase, C-terminal; Dihydrodipicolinate reductase, N-terminal; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: Dihydrodipicolinate reductase, bacterial/plant; IMG reference gene:2504122758; PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_004256143.1 COGs: COG0498 Threonine synthase; InterPro IPR004450:IPR001926; KEGG: dra:DR_A0360 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase; IMG reference gene:2504122759; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_004256144.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006345; KEGG: dge:Dgeo_0826 helicase RecD/TraA; SPTR: Helicase RecD/TraA; TIGRFAM: DNA helicase, RecD/TraA type; IMG reference gene:2504122761; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, putative, RecD/TraA family YP_004256145.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: dge:Dgeo_0798 hydrolase, putative; SPTR: Alpha/beta superfamily hydrolase; IMG reference gene:2504122763; PFAM: X-Pro dipeptidyl-peptidase (S15 family) YP_004256146.1 KEGG: ddr:Deide_02190 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122764 YP_004256147.1 COGs: COG0420 DNA repair exonuclease; InterPro IPR004593:IPR004843; KEGG: ddr:Deide_16180 putative exonuclease sbcCD, subunit D; PFAM: Metallo-dependent phosphatase; SPTR: Putative Exonuclease sbcCD, subunit D; TIGRFAM: Exonuclease SbcD; IMG reference gene:2504122765; PFAM: Calcineurin-like phosphoesterase; Type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD YP_004256148.1 COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: dge:Dgeo_0823 SMC protein-like protein; PFAM: RecF/RecN/SMC; SPTR: SbcC, ATPase involved in DNA repair; IMG reference gene:2504122766; PFAM: RecF/RecN/SMC N terminal domain YP_004256149.1 COGs: COG0461 Orotate phosphoribosyltransferase; KEGG: sti:Sthe_0937 orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; IMG reference gene:2504122767; PFAM: Phosphoribosyl transferase domain YP_004256150.1 KEGG: dra:DR_0592 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122768 YP_004256151.1 COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR014105:IPR002937; KEGG: ddr:Deide_2p01170 putative phytoene dehydrogenase; PFAM: Amine oxidase; SPTR: Putative phytoene dehydrogenase; TIGRFAM: Zeta-phytoene desaturase; IMG reference gene:2504122769; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase YP_004256152.1 COGs: COG4956 Integral membrane protein (PIN domain superfamily); InterPro IPR002716:IPR002792:IPR006596; KEGG: ddr:Deide_06940 hypothetical protein; PFAM: PilT protein, N-terminal; Deoxyribonuclease/rho motif-related TRAM; SMART: Nucleotide binding protein, PINc; SPTR: Putative uncharacterized protein; IMG reference gene:2504122771; PFAM: PIN domain YP_004256153.1 COGs: COG0533 Metal-dependent protease with possible chaperone activity; HAMAP: Peptidase M22, O-sialoglycoprotein peptidase; InterPro IPR022450:IPR017861:IPR000905; KEGG: dge:Dgeo_1057 putative DNA-binding/iron metalloprotein/AP endonuclease; PFAM: Peptidase M22, glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: Probable O-sialoglycoprotein endopeptidase; TIGRFAM: Peptidase M22, O-sialoglycoprotein peptidase; Peptidase M22, glycoprotease, subgroup; IMG reference gene:2504122772; PFAM: Glycoprotease family; TIGRFAM: putative glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family YP_004256154.1 KEGG: dge:Dgeo_1056 hypothetical protein; SPTR: Barstar-like nuclease inhibitor; IMG reference gene:2504122773 YP_004256155.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; HAMAP: Bacitracin resistance protein BacA; InterPro IPR003824; KEGG: dra:DR_0454 bacitracin resistance protein; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenyl-diphosphatase; TIGRFAM: Bacitracin resistance protein BacA; IMG reference gene:2504122774; PFAM: Bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP YP_004256156.1 COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: ddr:Deide_16080 putative acylglycerol lipase (monoacylglycerol lipase); PFAM: Alpha/beta hydrolase fold-1; PRIAM: Acylglycerol lipase; SPTR: Putative Acylglycerol lipase (Monoacylglycerol lipase); IMG reference gene:2504122775; PFAM: Putative lysophospholipase YP_004256157.1 KEGG: ddr:Deide_16050 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122776 YP_004256158.1 KEGG: ddr:Deide_16060 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122777; PFAM: Protein of unknown function (DUF1469) YP_004256159.1 COGs: COG0033 Phosphoglucomutase; InterProIPR005852:IPR005844:IPR005845:IPR005846:IPR 005843; KEGG: dge:Dgeo_1875 phosphoglucomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucomutase; SPTR: Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: Phosphoglucomutase, alpha-D-glucose specific; manually curated; IMG reference gene:2504122778; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific YP_004256160.1 InterPro IPR003088; KEGG: dge:Dgeo_2102 cytochrome c, class I; PFAM: Cytochrome c, class I; SPTR: Cytochrome c, class I; IMG reference gene:2504122779; PFAM: Cytochrome c YP_004256161.1 COGs: COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: dge:Dgeo_0283 molybdopterin-guanine dinucleotide biosynthesis protein A, putative; SPTR: Probable molybdopterin-guanine dinucleotide biosynthesis protein A; manually curated; IMG reference gene:2504122780 YP_004256162.1 COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: dge:Dgeo_0509 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase; IMG reference gene:2504122781; PFAM: Acylphosphatase YP_004256163.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: dge:Dgeo_0522 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1;4-b enzoquinolmethylase; IMG reference gene:2504122782; PFAM: Methyltransferase domain YP_004256164.1 KEGG: dra:DR_0877 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122785 YP_004256165.1 COGs: COG1823 Na+/dicarboxylate symporter; InterPro IPR001991; KEGG: bld:BLi00975 YhcL; PFAM: Sodium:dicarboxylate symporter; SPTR: L-cystine uptake protein tcyP; IMG reference gene:2504122786; PFAM: Sodium:dicarboxylate symporter family YP_004256166.1 COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: ddr:Deide_18120 dihydroorotase; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase; TIGRFAM: Dihydroorotase; IMG reference gene:2504122787; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type YP_004256167.1 KEGG: kpu:KP1_0383 outer membrane protein PgaA; SPTR: Putative outer membrane protein probably involved in nutrient binding; IMG reference gene:2504122788 YP_004256168.1 COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR002082:IPR006132:IPR006131; KEGG: dra:DR_1109 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504122789; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_004256169.1 COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; HAMAP: Bifunctional protein PyrR; InterPro IPR000836:IPR023050; KEGG: ddr:Deide_18100 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Bifunctional protein pyrR; IMG reference gene:2504122790; PFAM: Phosphoribosyl transferase domain YP_004256170.1 InterPro IPR015942; KEGG: ctc:CTC00409 putative glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122791; PFAM: Asp/Glu/Hydantoin racemase YP_004256171.1 COGs: COG0225 Peptide methionine sulfoxide reductase; HAMAP: Peptide methionine sulphoxide reductase MsrA; InterPro IPR002569; KEGG: dra:DR_1849 peptide methionine sulfoxide reductase; PFAM: Peptide methionine sulphoxide reductase MsrA; PRIAM: Peptide-methionine (S)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrA; TIGRFAM: Peptide methionine sulphoxide reductase MsrA; IMG reference gene:2504122792; PFAM: Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase YP_004256172.1 KEGG: dra:DR_1121 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122794 YP_004256173.1 COGs: COG3426 Butyrate kinase; InterPro IPR000890; KEGG: dge:Dgeo_1383 butyrate kinase; PFAM: Acetate/butyrate kinase; PRIAM: Butyrate kinase; SPTR: Acetate and butyrate kinase; IMG reference gene:2504122795; PFAM: Acetokinase family YP_004256174.1 COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265:IPR003651; KEGG: dra:DR_0928 endonuclease III, putative; PFAM: Endonuclease III-like, iron-sulphur cluster loop motif; HhH-GPD domain; SMART: HhH-GPD domain; SPTR: Endonuclease III, putative; IMG reference gene:2504122796; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004256175.1 KEGG: dge:Dgeo_0784 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122797 YP_004256176.1 KEGG: dra:DR_2003 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122798 YP_004256177.1 KEGG: ppp:PHYPADRAFT_142902 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122799 YP_004256178.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR012925; KEGG: mau:Micau_1065 TipAS antibiotic-recognition domain-containing protein; PFAM: TipAS antibiotic-recognition; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: TipAS antibiotic-recognition domain-containing protein; IMG reference gene:2504122800; PFAM: MerR family regulatory protein; TipAS antibiotic-recognition domain YP_004256179.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; HAMAP: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; InterPro IPR004588; KEGG: dra:DR_0386 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; IMG reference gene:2504122801; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004256180.1 KEGG: dra:DR_0387 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122802 YP_004256181.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; HAMAP: Tetrahydrofolate dehydrogenase/cyclohydrolase; InterPro IPR020630:IPR020631:IPR000672; KEGG: dge:Dgeo_0699 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methylenetetrahydrofolate dehydrogenase (NADP(+)); SPTR: Bifunctional protein folD 2; IMG reference gene:2504122803; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004256182.1 COGs: COG0781 Transcription termination factor; HAMAP: NusB antitermination factor; InterPro IPR011605:IPR006027; KEGG: dge:Dgeo_0698 NusB antitermination factor; PFAM: NusB/RsmB/TIM44; SPTR: N utilization substance protein B homolog; TIGRFAM: NusB antitermination factor; IMG reference gene:2504122804; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_004256183.1 COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: dra:DR_2068 alkaline shock protein-related protein; PFAM: Alkaline shock protein Asp23; SPTR: Alkaline shock protein-related protein; IMG reference gene:2504122805; PFAM: Protein of unknown function (DUF322) YP_004256184.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dge:Dgeo_2123 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type dipeptide transport system, permease component; IMG reference gene:2504122806; PFAM: Binding-protein-dependent transport system inner membrane component YP_004256185.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: ddr:Deide_19130 putative peptide/oligopeptide/nickel ABC transporter, permease component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Putative peptide/oligopeptide/nickel ABC transporter, permease component; IMG reference gene:2504122807; PFAM: Binding-protein-dependent transport system inner membrane component YP_004256186.1 KEGG: dra:DR_0359 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122808 YP_004256187.1 COGs: COG0354 aminomethyltransferase related to GcvT; InterPro IPR017703:IPR006222; KEGG: dge:Dgeo_2127 glycine cleavage T protein (aminomethyl transferase); PFAM: Glycine cleavage T-protein, N-terminal; SPTR: Glycine cleavage T protein (Aminomethyl transferase); TIGRFAM: Folate-binding, YgfZ; IMG reference gene:2504122809; PFAM: Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ YP_004256188.1 COGs: COG0373 Glutamyl-tRNA reductase; HAMAP: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase; InterPro IPR000343:IPR015895:IPR006151; KEGG: dge:Dgeo_2128 glutamyl-tRNA reductase; PFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: Glutamyl-tRNA reductase; TIGRFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase; IMG reference gene:2504122810; PFAM: Glutamyl-tRNAGlu reductase, N-terminal domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: glutamyl-tRNA reductase YP_004256189.1 COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: ddr:Deide_19180 putative porphyrin biosynthesis protein HemD (uroporphyrinogen-III C-methyltransferase and uroporphyrinogen-III synthase); PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III methyltransferase and synthase domains; IMG reference gene:2504122811; PFAM: Uroporphyrinogen-III synthase HemD YP_004256190.1 COGs: COG1160 GTPase; HAMAP: GTP-binding, EngA; InterPro IPR005225:IPR016484:IPR002917; KEGG: dge:Dgeo_2103 GTP-binding protein EngA; PFAM: GTP-binding protein, HSR1-related; SPTR: GTPase Der; TIGRFAM: GTP-binding, EngA; Small GTP-binding protein; IMG reference gene:2504122812; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain YP_004256191.1 KEGG: ddr:Deide_18980 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122813 YP_004256192.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR004540:IPR005225:IPR000795:IPR004161:IPR 005517:IPR000640; KEGG: dge:Dgeo_1871 elongation factor G; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G; TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein; IMG reference gene:2504122814; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004256193.1 COGs: COG0049 Ribosomal protein S7; InterPro IPR005717:IPR000235; KEGG: dra:DR_0306 30S ribosomal protein S7; PFAM: Ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: Ribosomal protein S7, bacterial-type; IMG reference gene:2504122815; PFAM: Ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle YP_004256194.1 COGs: COG0048 Ribosomal protein S12; InterPro IPR005679:IPR006032; KEGG: dge:Dgeo_1873 30S ribosomal protein S12; PFAM: Ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: Ribosomal protein S12, bacteria; IMG reference gene:2504122816; PFAM: Ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle YP_004256195.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: dge:Dgeo_0648 ABC transporter related; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type transport system, ATPase and permease component; IMG reference gene:2504122817; PFAM: ABC transporter transmembrane region; ABC transporter YP_004256196.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: dge:Dgeo_0647 ABC transporter related; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type multidrug transport system, ATPase and permease component; IMG reference gene:2504122818; PFAM: ABC transporter; ABC transporter transmembrane region YP_004256197.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR004541:IPR005225:IPR000795:IPR004161:IPR 004160; KEGG: ddr:Deide_18970 elongation factor Tu; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; SPTR: Elongation factor Tu; TIGRFAM: Translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; IMG reference gene:2504122822; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004256198.1 COGs: COG0254 Ribosomal protein L31; HAMAP: Ribosomal protein L31; InterPro IPR002150; KEGG: dra:DR_0825 50S ribosomal protein L31; PFAM: Ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: Ribosomal protein L31; IMG reference gene:2504122823; PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_004256199.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR003029:IPR022967; KEGG: dge:Dgeo_1577 30S ribosomal protein S1; PFAM: Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: RNA binding S1; IMG reference gene:2504122824; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1 YP_004256200.1 COGs: COG0228 Ribosomal protein S16; HAMAP: Ribosomal protein S16; InterPro IPR000307; KEGG: dra:DR_1294 30S ribosomal protein S16; PFAM: Ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: Ribosomal protein S16; IMG reference gene:2504122825; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_004256201.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: dge:Dgeo_1595 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; PRIAM: 3-hydroxybutyryl-CoA dehydratase; SPTR: Enoyl-CoA hydratase/isomerase; IMG reference gene:2504122826; PFAM: Enoyl-CoA hydratase/isomerase family YP_004256202.1 COGs: COG3294 conserved hypothetical protein; KEGG: dra:DR_1443 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122827 YP_004256203.1 COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: dge:Dgeo_1593 VanW; PFAM: Vancomycin resistance VanW; SPTR: VanW; IMG reference gene:2504122828; PFAM: Putative peptidoglycan binding domain; VanW like protein YP_004256204.1 KEGG: dra:DR_1256 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122829 YP_004256205.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: dra:DR_1255 acyl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase; IMG reference gene:2504122830; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004256206.1 COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR001604:IPR020821; KEGG: gbm:Gbem_2089 DNA/RNA non-specific endonuclease; PFAM: DNA/RNA non-specific endonuclease; SMART: DNA/RNA non-specific endonuclease; Extracellular Endonuclease, subunit A; SPTR: DNA/RNA non-specific endonuclease; IMG reference gene:2504122831; PFAM: DNA/RNA non-specific endonuclease YP_004256207.1 COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR000297; KEGG: dra:DR_1063 peptidyl-prolyl cis-trans isomerase C; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: Peptidyl-prolyl cis-trans isomerase C; IMG reference gene:2504122832; PFAM: PPIC-type PPIASE domain YP_004256208.1 InterPro IPR011701; KEGG: dge:Dgeo_0892 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504122833; PFAM: Major Facilitator Superfamily YP_004256209.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: dge:Dgeo_0665 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2504122834; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004256210.1 InterPro IPR008554; KEGG: dra:DR_0057 hypothetical protein; PFAM: Glutaredoxin-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504122835; PFAM: Glutaredoxin-like domain (DUF836) YP_004256211.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR004390:IPR000897:IPR013822:IPR003593; KEGG: ddr:Deide_13740 putative cell division protein FtsY, signal recognition particle-docking protein FtsY; PFAM: Signal recognition particle, SRP54 subunit, GTPase; SMART: Signal recognition particle, SRP54 subunit, GTPase; ATPase, AAA+ type, core; Signal recognition particle, SRP54 subunit, helical bundle; SPTR: Putative Cell division protein ftsY, Signal recognition particle-docking protein FtsY; TIGRFAM: Cell division transporter substrate-binding protein FtsY; IMG reference gene:2504122836; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_004256212.1 COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004562:IPR004143:IPR019491; KEGG: msu:MS1058 LplA protein; PFAM: Lipoate protein ligase, C-terminal; Biotin/lipoate A/B protein ligase; SPTR: Putative uncharacterized protein; TIGRFAM: Lipoyltransferase/lipoate-protein ligase; IMG reference gene:2504122837; PFAM: Bacterial lipoate protein ligase C-terminus; Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoyltransferase and lipoate-protein ligase YP_004256213.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR003141; KEGG: ddr:Deide_07030 putative DNA polymerase, family X; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: Putative DNA polymerase, family X; IMG reference gene:2504122838; PFAM: PHP domain YP_004256214.1 KEGG: psa:PST_2663 DEAD-box ATP dependent DNA helicase; IMG reference gene:2504122840 YP_004256215.1 COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: dra:DR_1839 peptidyl-prolyl cis-trans isomerase, FKBP-type; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504122841; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004256216.1 InterPro IPR000223:IPR019759; KEGG: dra:DR_1321 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; IMG reference gene:2504122842; PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type YP_004256217.1 KEGG: dra:DR_1320 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122843 YP_004256218.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: dra:DR_0658 hypothetical protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504122844; PFAM: Metallo-beta-lactamase superfamily YP_004256219.1 COGs: COG0657 Esterase/lipase; InterPro IPR013094; KEGG: dge:Dgeo_0856 alpha/beta hydrolase fold-3; SPTR: Alpha/betasuperfamily hydrolase; IMG reference gene:2504122845; PFAM: alpha/beta hydrolase fold YP_004256220.1 KEGG: sro:Sros_3388 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122846 YP_004256221.1 COGs: COG0481 Membrane GTPase LepA; HAMAP: GTP-binding protein LepA; InterProIPR005225:IPR006297:IPR000795:IPR004161:IPR 000640:IPR013842; KEGG: dra:DR_1145 GTP-binding protein LepA; PFAM: GTP-binding protein LepA, C-terminal; Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SMART: Translation elongation factor EFG/EF2, C-terminal; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; Small GTP-binding protein; IMG reference gene:2504122847; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004256222.1 COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006056:IPR006175; KEGG: pcr:Pcryo_0250 endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: Endoribonuclease L-PSP; TIGRFAM: YjgF-like protein; IMG reference gene:2504122848; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative YP_004256223.1 COGs: COG4147 symporter; InterPro IPR019899:IPR001734; KEGG: cpb:Cphamn1_1771 Na+/solute symporter; PFAM: Sodium/solute symporter; SPTR: Na+/solute symporter; TIGRFAM: Sodium/solute symporter, VC2705 subfamily; IMG reference gene:2504122849; PFAM: Sodium:solute symporter family; TIGRFAM: probable sodium:solute symporter, VC_2705 subfamily YP_004256224.1 COGs: COG4327 membrane protein; InterPro IPR019886; KEGG: tra:Trad_0254 putative solute symporter protein; SPTR: Putative solute symporter protein; TIGRFAM: Sodium symporter small subunit, predicted; IMG reference gene:2504122850; TIGRFAM: putative solute:sodium symporter small subunit YP_004256225.1 KEGG: oih:OB1638 hypothetical protein; SPTR: Putative uncharacterized protein OB1638; IMG reference gene:2504122851 YP_004256226.1 KEGG: aac:Aaci_1602 protein of unknown function DUF893 YccS/YhfK; SPTR: Putative uncharacterized protein; IMG reference gene:2504122852 YP_004256227.1 COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: dge:Dgeo_0231 PSP1; PFAM: PSP1, C-terminal; SPTR: PSP1; IMG reference gene:2504122854; PFAM: PSP1 C-terminal conserved region YP_004256228.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: rec:RHECIAT_CH0003658 probable transcriptional regulator protein, LacI family; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Probable transcriptional regulator protein, LacI family; IMG reference gene:2504122856; PFAM: Bacterial regulatory proteins, lacI family; family YP_004256229.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: dra:DR_A0055 ribokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Ribokinase; SPTR: Ribokinase; IMG reference gene:2504122857; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase YP_004256230.1 COGs: COG1869 ABC-type ribose transport system auxiliary component; HAMAP: D-ribose pyranase; InterPro IPR007721:IPR023064; KEGG: gtn:GTNG_3173 D-ribose pyranase; PFAM: D-ribose pyranase RbsD/L-fucose mutarotase FucU; SPTR: D-ribose pyranase; IMG reference gene:2504122858; PFAM: RbsD / FucU transport protein family YP_004256231.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ava:Ava_2172 ABC transporter-like; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Ribose import ATP-binding protein RbsA; IMG reference gene:2504122859; PFAM: ABC transporter YP_004256232.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: gmc:GY4MC1_0217 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Monosaccharide-transporting ATPase; IMG reference gene:2504122860; PFAM: Branched-chain amino acid transport system / permease component YP_004256233.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: drm:Dred_2522 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: ABC-type ribose transport system; IMG reference gene:2504122861; PFAM: family YP_004256234.1 KEGG: mno:Mnod_7371 DNA mismatch repair protein MutL; SPTR: Protein kinase domain; IMG reference gene:2504122862 YP_004256235.1 InterPro IPR002559; KEGG: ddr:Deide_3p01971 putative transposase; PFAM: Transposase, IS4-like; SPTR: Putative transposase; IMG reference gene:2504122863; PFAM: Transposase DDE domain YP_004256236.1 COGs: COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478 contains von Willebrand factor (vWF) domain; InterPro IPR002035; KEGG: mbn:Mboo_0637 von Willebrand factor, type A; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor, type A; IMG reference gene:2504122865; PFAM: von Willebrand factor type A domain YP_004256237.1 KEGG: bge:BC1002_0438 serine/threonine phosphoprotein phosphatase; SPTR: Serine/threonine phosphoprotein phosphatase; IMG reference gene:2504122866 YP_004256238.1 COGs: COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains; KEGG: xca:xccb100_3124 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504122867; PFAM: Protein kinase domain YP_004256239.1 KEGG: cbt:CLH_1614 putative permease; SPTR: Putative permease; IMG reference gene:2504122868 YP_004256240.1 COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR004473:IPR007409:IPR006935:IPR014001; KEGG: tjr:TherJR_0901 type I site-specific deoxyribonuclease, HsdR family; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal; SPTR: Type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: Restriction endonuclease, type I, EcoRI, R subunit; IMG reference gene:2504122869; PFAM: Domain of unknown function (DUF3387); Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family YP_004256241.1 COGs: COG1479 conserved hypothetical protein; InterPro IPR004919:IPR011089; KEGG: fma:FMG_1371 hypothetical protein; PFAM: Domain of unknown function DUF262; Domain of unknown function DUF1524 RloF; SPTR: Putative uncharacterized protein; IMG reference gene:2504122870; PFAM: Protein of unknown function (DUF1524); Protein of unknown function DUF262 YP_004256242.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: slp:Slip_1127 site-specific DNA-methyltransferase (adenine-specific); PFAM: DNA methylase, adenine-specific; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Site-specific DNA-methyltransferase (Adenine-specific); IMG reference gene:2504122872; PFAM: N-6 DNA Methylase; HsdM N-terminal domain YP_004256243.1 InterPro IPR010852; KEGG: amd:AMED_3109 hypothetical protein; PFAM: Protein of unknown function DUF1470; SPTR: Putative uncharacterized protein; IMG reference gene:2504122873 YP_004256244.1 InterPro IPR010093; KEGG: mau:Micau_0014 excisionase family DNA binding domain-containing protein; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: Excisionase/Xis, DNA-binding; IMG reference gene:2504122874; TIGRFAM: DNA binding domain, excisionase family YP_004256245.1 KEGG: osa:4326983 Os01g0329300; SPTR: Os01g0329300 protein; IMG reference gene:2504122875 YP_004256246.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterPro IPR006674:IPR003607; KEGG: ava:Ava_1993 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504122876; PFAM: HD domain YP_004256247.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: ypb:YPTS_4096 hypothetical protein; PFAM: Protein of unknown function DUF45; SPTR: Putative uncharacterized protein; IMG reference gene:2504122877; PFAM: Protein of unknown function DUF45 YP_004256248.1 COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR004473:IPR007409:IPR006935:IPR014001; KEGG: mca:MCA1893 type I restriction-modification system, R subunit; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal; SPTR: Type I restriction-modification system, R subunit; TIGRFAM: Restriction endonuclease, type I, EcoRI, R subunit; IMG reference gene:2504122878; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family YP_004256249.1 KEGG: cti:RALTA_A1004 putative transcriptional regulator, LysR family; SPTR: Putative transcriptional regulator, LysR family; IMG reference gene:2504122879 YP_004256250.1 COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: tme:Tmel_0403 restriction modification system DNA specificity subunit; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Restriction modification system DNA specificity domain; IMG reference gene:2504122881; PFAM: Type I restriction modification DNA specificity domain YP_004256251.1 COGs: COG4823 Abortive infection bacteriophage resistance protein; InterPro IPR011664; KEGG: lpp:plpp0049 hypothetical protein; PFAM: Abortive infection bacteriophage resistance-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504122882; PFAM: Abi-like protein YP_004256252.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR004546:IPR003356; KEGG: mmq:MmarC5_0614 type I restriction-modification system, M subunit; PFAM: DNA methylase, adenine-specific; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system, M subunit; TIGRFAM: Restriction endonuclease, type I, EcoRI, M subunit; IMG reference gene:2504122883; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004256253.1 InterPro IPR001387; KEGG: hit:NTHI1517 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Helix-turn-helix; IMG reference gene:2504122884; PFAM: Helix-turn-helix YP_004256254.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: dra:DR_0513 integrase, putative; PFAM: Integrase, catalytic core, phage; SPTR: Integrase, putative; IMG reference gene:2504122885; PFAM: Phage integrase family YP_004256255.1 COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371:IPR000537; KEGG: dge:Dgeo_2322 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase, putative; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase-related; IMG reference gene:2504122889; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase YP_004256256.1 KEGG: dra:DR_0849 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122890 YP_004256257.1 COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); KEGG: dge:Dgeo_2319 putative adenylate/guanylate cyclase; SPTR: Putative adenylate/guanylate cyclase; IMG reference gene:2504122891 YP_004256258.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ddr:Deide_01470 putative response regulator, CheY; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Response regulator; IMG reference gene:2504122892; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004256259.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: dge:Dgeo_2317 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2504122893; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004256260.1 COGs: COG1438 Arginine repressor; HAMAP: Arginine repressor; InterPro IPR001669:IPR020900:IPR020899; KEGG: dge:Dgeo_2316 arginine repressor, ArgR; PFAM: Arginine repressor, DNA-binding domain; Arginine repressor, C-terminal; SPTR: Arginine repressor; TIGRFAM: Arginine repressor; IMG reference gene:2504122894; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_004256261.1 COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR005252:IPR003382:IPR007085; KEGG: ddr:Deide_01500 putative coenzyme A biosynthesis bifunction; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein; PRIAM: Phosphopantothenate--cysteine ligase; SPTR: Putative Coenzyme A biosynthesis bifunction; TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; IMG reference gene:2504122895; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_004256262.1 KEGG: dge:Dgeo_2311 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122896 YP_004256263.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR005936:IPR011546:IPR003959:IPR000642:IPR 003593; KEGG: ddr:Deide_01120 putative cell division protease FtsH; putative membrane protein; PFAM: Peptidase M41; ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative cell division protease ftsH; putative membrane protein; TIGRFAM: Peptidase M41, FtsH; IMG reference gene:2504122897; PFAM: FtsH Extracellular; Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004256264.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277; KEGG: dra:DR_2186 O-acetylhomoserine (thiol)-lyase/O-acetylserine (thiol)-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine (Thiol)-lyase/O-acetylserine (Thiol)-lyase; IMG reference gene:2504122898; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004256265.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544; KEGG: mcu:HMPREF0573_11483 branched-subunit-amino-acid transaminase; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid transaminase; TIGRFAM: Branched-chain amino acid aminotransferase II; IMG reference gene:2504122899; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II YP_004256266.1 InterPro IPR000086; KEGG: dra:DR_2204 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2504122900; PFAM: NUDIX domain YP_004256267.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR001498; KEGG: ddr:Deide_02640 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504122901; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family YP_004256268.1 COGs: COG0486 GTPase; HAMAP: tRNA modification GTPase TrmE; InterPro IPR004520:IPR005225:IPR018948:IPR002917; KEGG: dge:Dgeo_0478 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE, N-terminal; GTP-binding protein, HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; Small GTP-binding protein; IMG reference gene:2504122902; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: small GTP-binding protein domain; tRNA modification GTPase TrmE YP_004256269.1 KEGG: cmi:CMM_0325 putative ABC transporter (fused permease/ATPase); SPTR: Putative ABC transporter (Fused permease/ATPase); IMG reference gene:2504122904 YP_004256270.1 COGs: COG0563 Adenylate kinase and related kinase; KEGG: dra:DR_0202 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122905 YP_004256271.1 KEGG: dra:DR_1251 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122906 YP_004256272.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: ddr:Deide_08850 putative protease, peptidase U32 family; PFAM: Peptidase U32; SPTR: Putative Protease, Peptidase U32 family; IMG reference gene:2504122907; PFAM: Collagenase; Peptidase family U32 YP_004256273.1 InterPro IPR011528; KEGG: dap:Dacet_0707 NERD domain protein; PFAM: NERD; SPTR: NERD domain protein; IMG reference gene:2504122908; PFAM: Nuclease-related domain YP_004256274.1 InterPro IPR011701; KEGG: dge:Dgeo_1065 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504122909; PFAM: Major Facilitator Superfamily; Uncharacterised BCR, YnfA/UPF0060 family YP_004256275.1 InterPro IPR000834; KEGG: hch:HCH_04864 carboxypeptidase; PFAM: Peptidase M14, carboxypeptidase A; PRIAM: Carboxypeptidase A., Aqualysin 1; SMART: Peptidase M14, carboxypeptidase A; SPTR: Predicted carboxypeptidase; IMG reference gene:2504122910; PFAM: Zinc carboxypeptidase YP_004256276.1 KEGG: ddr:Deide_11250 putative rhodanese sulfurtransferase; SPTR: Putative rhodanese sulfurtransferase; IMG reference gene:2504122911 YP_004256277.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: dge:Dgeo_1280 rhodanese-like protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese-like protein; IMG reference gene:2504122912; PFAM: Rhodanese-like domain YP_004256278.1 COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: dge:Dgeo_1281 hypothetical protein; PFAM: Domain of unknown function DUF59; SPTR: Putative uncharacterized protein; IMG reference gene:2504122913; PFAM: Domain of unknown function DUF59 YP_004256279.1 COGs: COG2738 Zn-dependent protease; InterPro IPR007395; KEGG: dra:DR_0194 hypothetical protein; PFAM: Peptidase, membrane zinc metallopeptidase, putative; SPTR: Putative uncharacterized protein; IMG reference gene:2504122914; PFAM: Putative neutral zinc metallopeptidase YP_004256280.1 COGs: COG2359 conserved hypothetical protein; InterPro IPR007347; KEGG: dge:Dgeo_1283 stage V sporulation protein S; PFAM: Stage V sporulation protein S; SPTR: SpoVS related protein; IMG reference gene:2504122915; PFAM: Stage V sporulation protein S (SpoVS) YP_004256281.1 COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: dra:DR_2465 serine-pyruvate aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Serine-pyruvate aminotransferase; IMG reference gene:2504122916; PFAM: Aminotransferase class-V YP_004256282.1 InterPro IPR013105:IPR011717:IPR019734; KEGG: dge:Dgeo_0876 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-4; SPTR: P-loop ATPase, LuxR family containing TPR repeats; IMG reference gene:2504122917 YP_004256283.1 COGs: COG2225 Malate synthase; InterPro IPR006252:IPR001465; KEGG: ddr:Deide_11990 malate synthase; PFAM: Malate synthase; PRIAM: Malate synthase; SPTR: Malate synthase; TIGRFAM: Malate synthase A; IMG reference gene:2504122918; PFAM: Malate synthase; TIGRFAM: malate synthase A YP_004256284.1 COGs: COG2224 Isocitrate lyase; InterPro IPR006254:IPR000918; KEGG: ddr:Deide_11980 putative isocitrate lyase (isocitrase)(isocitratase)(ICL); PFAM: Isocitrate lyase/phosphorylmutase; PRIAM: Isocitrate lyase; SPTR: Isocitrate lyase; TIGRFAM: Isocitrate lyase; IMG reference gene:2504122919; PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase YP_004256285.1 COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; HAMAP: Acetate-CoA ligase; InterPro IPR011904:IPR000873; KEGG: dge:Dgeo_1759 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: Acetyl-coenzyme A synthetase; TIGRFAM: Acetate-CoA ligase; IMG reference gene:2504122920; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase YP_004256286.1 COGs: COG2124 Cytochrome P450; InterPro IPR001128; KEGG: dra:DR_2538 cytochrome P450; PFAM: Cytochrome P450; SPTR: Cytochrome P450; IMG reference gene:2504122921; PFAM: Cytochrome P450 YP_004256287.1 KEGG: fal:FRAAL5568 antibiotic resistance protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122922 YP_004256288.1 KEGG: ddr:Deide_2p00110 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122923 YP_004256289.1 COGs: COG0423 Glycyl-tRNA synthetase (class II); InterPro IPR002315:IPR002314:IPR004154; KEGG: dra:DR_2059 glycyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase; TIGRFAM: Glycyl-tRNA synthetase, alpha2 dimer; IMG reference gene:2504122924; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: glycyl-tRNA synthetase, dimeric type YP_004256290.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: ddr:Deide_07270 hypothetical protein; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504122925; PFAM: Phosphoglycerate mutase family YP_004256291.1 KEGG: ddr:Deide_03710 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122926 YP_004256292.1 KEGG: dge:Dgeo_1717 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122927 YP_004256293.1 KEGG: ddr:Deide_12690 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122928 YP_004256294.1 COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: dge:Dgeo_0719 electron transfer flavoprotein beta-subunit; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein beta-subunit; IMG reference gene:2504122929; PFAM: Electron transfer flavoprotein domain YP_004256295.1 COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731; KEGG: ddr:Deide_12710 putative electron transfer flavoprotein subunit alpha (alpha-ETF) (electron transfer flavoprotein large subunit) (ETFLS); PFAM: Electron transfer flavoprotein, alpha subunit, C-terminal; Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Putative Electron transfer flavoprotein subunit alpha (Alpha-ETF) (Electron transfer flavoprotein large subunit) (ETFLS); IMG reference gene:2504122930; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain YP_004256296.1 KEGG: dge:Dgeo_0721 hypothetical protein; SPTR: Phospholipase A2; IMG reference gene:2504122931; PFAM: Prokaryotic phospholipase A2 YP_004256297.1 COGs: COG3429 Glucose-6-P dehydrogenase subunit; InterPro IPR019297; KEGG: ddr:Deide_16470 putative glucose-6-P dehydrogenase subunit; PFAM: Glucose-6-phosphate dehydrogenase subunit; SPTR: Putative glucose-6-P dehydrogenase subunit; IMG reference gene:2504122932; PFAM: Glucose-6-phosphate dehydrogenase subunit YP_004256298.1 COGs: COG0364 Glucose-6-phosphate 1-dehydrogenase; InterPro IPR001282:IPR022674:IPR022675; KEGG: dra:DR_1596 glucose-6-phosphate 1-dehydrogenase; PFAM: Glucose-6-phosphate dehydrogenase, C-terminal; Glucose-6-phosphate dehydrogenase, NAD-binding; PRIAM: Glucose-6-phosphate dehydrogenase; SPTR: Glucose-6-phosphate 1-dehydrogenase; TIGRFAM: Glucose-6-phosphate dehydrogenase; IMG reference gene:2504122933; PFAM: Glucose-6-phosphate dehydrogenase, NAD binding domain; Glucose-6-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase YP_004256299.1 COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR004849:IPR006115:IPR006114; KEGG: dge:Dgeo_1973 6-phosphogluconate dehydrogenase-like protein; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; 6-phosphogluconate dehydrogenase, C-terminal; PRIAM: Phosphogluconate dehydrogenase (decarboxylating); SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase-related protein; IMG reference gene:2504122934; PFAM: 6-phosphogluconate dehydrogenase, C-terminal domain; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating) YP_004256300.1 InterPro IPR003675; KEGG: syr:SynRCC307_0866 metal-dependent membrane protease; PFAM: Abortive infection protein; SPTR: Predicted metal-dependent membrane protease; IMG reference gene:2504122935; PFAM: CAAX amino terminal protease family YP_004256301.1 KEGG: dra:DR_1590 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122936; PFAM: Polyketide cyclase / dehydrase and lipid transport YP_004256302.1 COGs: COG3296 conserved hypothetical protein; KEGG: ddr:Deide_07450 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122937 YP_004256303.1 COGs: COG0328 Ribonuclease HI; HAMAP: Ribonuclease H; InterPro IPR002156:IPR022892; KEGG: dra:DR_0899 ribonuclease H; PFAM: Ribonuclease H domain; PRIAM: Ribonuclease H; SPTR: Ribonuclease H; IMG reference gene:2504122938; PFAM: RNase H YP_004256304.1 COGs: COG1378 transcriptional regulator protein; InterPro IPR002831; KEGG: ddr:Deide_05870 putative transcriptional regulator; PFAM: Transcription regulator TrmB, N-terminal; SPTR: Putative transcriptional regulator; IMG reference gene:2504122939; PFAM: Sugar-specific transcriptional regulator TrmB YP_004256305.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tra:Trad_0799 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; IMG reference gene:2504122942; PFAM: Methyltransferase domain YP_004256306.1 COGs: COG3665 conserved hypothetical protein; InterPro IPR018959; KEGG: dra:DR_0613 hypothetical protein; PFAM: Domain of unknown function DUF1989; SPTR: Putative uncharacterized protein; IMG reference gene:2504122943; PFAM: Domain of unknown function (DUF1989) YP_004256307.1 COGs: COG3403 conserved hypothetical protein; InterPro IPR014988; KEGG: dra:DR_0614 hypothetical protein; PFAM: Uncharacterised protein family, YqcI/YcgG; SPTR: Putative uncharacterized protein; IMG reference gene:2504122944; PFAM: YqcI/YcgG family YP_004256308.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: dra:DR_2333 NADH oxidase-related protein; PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal; PRIAM: NADPH dehydrogenase; SPTR: NADH oxidase-related protein; IMG reference gene:2504122945; PFAM: NADH:flavin oxidoreductase / NADH oxidase family YP_004256309.1 COGs: COG2272 Carboxylesterase type B; InterPro IPR002018; KEGG: dra:DR_2626 carboxylesterase, type B; PFAM: Carboxylesterase, type B; PRIAM: Carboxylesterase; SPTR: Carboxylesterase, type B; IMG reference gene:2504122946; PFAM: Carboxylesterase YP_004256310.1 COGs: COG2329 Uncharacterized protein involved in biosynthesis of extracellular polysaccharides; InterPro IPR007138; KEGG: dra:DR_0272 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504122947; PFAM: Antibiotic biosynthesis monooxygenase YP_004256311.1 KEGG: dge:Dgeo_1692 LysR family transcriptional regulator; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504122948 YP_004256312.1 COGs: COG1225 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0990 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; IMG reference gene:2504122949; PFAM: AhpC/TSA family YP_004256313.1 COGs: COG2234 aminopeptidase; InterPro IPR007484:IPR003961; KEGG: rbi:RB2501_00456 probable aminopeptidase fused to fibronectin type 3 domain; PFAM: Peptidase M28; Fibronectin, type III; SMART: Fibronectin, type III; SPTR: Peptidase, M28 family; IMG reference gene:2504122950; PFAM: Fibronectin type III domain; Peptidase family M28 YP_004256314.1 COGs: COG3531 protein-disulfide isomerase; KEGG: rer:RER_55190 hypothetical protein; SPTR: Thioredoxin; IMG reference gene:2504122951; PFAM: DSBA-like thioredoxin domain YP_004256315.1 InterPro IPR005151; KEGG: sds:SDEG_0979 putative nisin-resistanceprotein; PFAM: Peptidase S41; SPTR: NisR; IMG reference gene:2504122952; PFAM: Peptidase family S41 YP_004256316.1 KEGG: aoe:Clos_1272 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122953 YP_004256317.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: dra:DR_2357 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; IMG reference gene:2504122954; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial YP_004256318.1 InterPro IPR000086; KEGG: dra:DR_2356 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2504122955; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein YP_004256319.1 COGs: COG2105 conserved hypothetical protein; InterPro IPR000086:IPR009288; KEGG: fnu:FN1108 phosphohydrolase (MutT/NUDIX family protein); PFAM: AIG2-like; NUDIX hydrolase domain; SPTR: Possible NTP pyrophosphohydrolase; IMG reference gene:2504122956; PFAM: NUDIX domain; AIG2-like family YP_004256320.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 1, bacterial; InterPro IPR004529:IPR004188:IPR002319:IPR022911; KEGG: ddr:Deide_20900 phenylalanyl-tRNA synthetase subunit alpha; PFAM: Phenylalanyl-tRNA synthetase; Phenylalanyl-tRNA synthetase, class II, N-terminal; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; IMG reference gene:2504122957; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_004256321.1 COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006153:IPR006037; KEGG: dge:Dgeo_0222 potassium/proton antiporter; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504122958; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family YP_004256322.1 COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: dge:Dgeo_0221 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase; IMG reference gene:2504122959; PFAM: Serine hydroxymethyltransferase YP_004256323.1 KEGG: dra:DR_2179 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122960 YP_004256324.1 COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: dra:DR_2180 hypothetical protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504122961; PFAM: Roadblock/LC7 domain YP_004256325.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: dra:DR_1613 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family; IMG reference gene:2504122962; PFAM: Bacterial regulatory protein, arsR family YP_004256326.1 HAMAP: DNA-directed RNA polymerase, omega subunit; InterPro IPR003716:IPR006110; KEGG: dra:DR_2494 DNA-directed RNA polymerase subunit omega; PFAM: RNA polymerase, subunit omega/K/RPABC2; SPTR: DNA-directed RNA polymerase subunit omega; TIGRFAM: DNA-directed RNA polymerase, omega subunit; IMG reference gene:2504122963; PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_004256327.1 KEGG: pjd:Pjdr2_2809 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122964 YP_004256328.1 COGs: COG0219 rRNA methylase (SpoU class); InterPro IPR001537; KEGG: dge:Dgeo_0072 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: tRNA/rRNA methyltransferase (SpoU); IMG reference gene:2504122965; PFAM: SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, putative, group 2 YP_004256329.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; HAMAP: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; InterPro IPR003526; KEGG: dra:DR_0230 hypothetical protein; PFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; PRIAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; IMG reference gene:2504122966; PFAM: YgbB family; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004256330.1 KEGG: rfr:Rfer_2897 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122967 YP_004256331.1 InterPro IPR007452; KEGG: ddr:Deide_16100 conserved hypothetical protein, precursor; PFAM: Protein of unknown function DUF490; SPTR: Putative uncharacterized protein; IMG reference gene:2504122968; PFAM: Family of unknown function (DUF490) YP_004256332.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003439:IPR003593; KEGG: dra:DR_2404 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein, MsbA family; IMG reference gene:2504122969; PFAM: ABC transporter; ABC transporter transmembrane region YP_004256333.1 KEGG: ddr:Deide_17501 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122970 YP_004256334.1 COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); HAMAP: DNA mismatch repair protein, MutL; InterProIPR014763:IPR003594:IPR013507:IPR014790:IPR 020667; KEGG: dge:Dgeo_1538 DNA mismatch repair protein MutL; PFAM: MutL, C-terminal, dimerisation; DNA mismatch repair protein, C-terminal; ATPase-like, ATP-binding domain; SMART: MutL, C-terminal, dimerisation; SPTR: DNA mismatch repair protein mutL; TIGRFAM: DNA mismatch repair protein, N-terminal; IMG reference gene:2504122971; PFAM: MutL C terminal dimerisation domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL YP_004256335.1 KEGG: enc:ECL_02787 glycoside hydrolase family 18 protein; SPTR: Reductase RED1; IMG reference gene:2504122972 YP_004256336.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR005748:IPR007695:IPR007860:IPR007696:IPR 007861:IPR000432; KEGG: dge:Dgeo_1537 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; DNA mismatch repair protein MutS-like, N-terminal; DNA mismatch repair protein MutS, connector; DNA mismatch repair protein MutS, clamp; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; SPTR: DNA mismatch repair protein MutS; TIGRFAM: DNA mismatch repair protein MutS, type 1; IMG reference gene:2504122973; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair protein MutS YP_004256337.1 COGs: COG0102 Ribosomal protein L13; InterPro IPR005823:IPR005822; KEGG: ddr:Deide_07320 50S ribosomal protein L13; PFAM: Ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: Ribosomal protein L13, bacterial-type; IMG reference gene:2504122974; PFAM: Ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type YP_004256338.1 COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: dge:Dgeo_1735 30S ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9; IMG reference gene:2504122975; PFAM: Ribosomal protein S9/S16 YP_004256339.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006379:IPR013200; KEGG: ddr:Deide_07250 putative hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Putative hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504122976; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB YP_004256340.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006379:IPR013200; KEGG: dge:Dgeo_1737 HAD family hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: HAD-superfamily hydrolase subfamily IIB; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504122977; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB YP_004256341.1 COGs: COG0756 dUTPase; InterPro IPR008180; KEGG: lmo:lmo1691 hypothetical protein; PFAM: DeoxyUTP pyrophosphatase domain; SPTR: Deoxyuridine 5'-triphosphate nucleotidohydrolase; IMG reference gene:2504122978; PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) YP_004256342.1 COGs: COG0335 Ribosomal protein L19; HAMAP: Ribosomal protein L19; InterPro IPR001857; KEGG: ddr:Deide_07240 50S ribosomal protein L19; PFAM: Ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: Ribosomal protein L19; IMG reference gene:2504122979; PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_004256343.1 InterPro IPR000073; KEGG: rer:RER_14060 hydrolase; PFAM: Alpha/beta hydrolase fold-1; SPTR: Putative hydrolase; manually curated; IMG reference gene:2504122980; PFAM: alpha/beta hydrolase fold YP_004256344.1 COGs: COG0321 Lipoate-protein ligase B; HAMAP: Octanoyltransferase; InterPro IPR000544:IPR004143; KEGG: ddr:Deide_07220 putative lipoate-protein ligase B (lipoyltransferase); PFAM: Biotin/lipoate A/B protein ligase; PRIAM: Lipoyl(octanoyl) transferase; SPTR: Octanoyltransferase; TIGRFAM: Octanoyltransferase; IMG reference gene:2504122981; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B YP_004256345.1 COGs: COG0320 Lipoate synthase; HAMAP: Lipoate synthase; InterPro IPR003698:IPR007197:IPR006638; KEGG: ddr:Deide_07210 lipoyl synthase; PFAM: Radical SAM; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoyl synthase; TIGRFAM: Lipoate synthase; IMG reference gene:2504122982; PFAM: Radical SAM superfamily; TIGRFAM: lipoate synthase YP_004256346.1 KEGG: dra:DR_A0190 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122983 YP_004256347.1 InterPro IPR000620; KEGG: reh:H16_A0077 PecM protein; PFAM: Drug/metabolite transporter; SPTR: Predicted PecM protein; IMG reference gene:2504122984; PFAM: EamA-like transporter family YP_004256348.1 COGs: COG4067 conserved hypothetical protein; InterPro IPR008503; KEGG: dat:HRM2_29420 RimK2; PFAM: Protein of unknown function DUF785; SPTR: RimK2; IMG reference gene:2504122985; PFAM: Protein of unknown function (DUF785) YP_004256349.1 COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); HAMAP: Ribosomal protein S6 modification protein; InterPro IPR004666:IPR013651; KEGG: cyc:PCC7424_3661 alpha-L-glutamate ligase, RimK family; PFAM: ATP-grasp fold, RimK-type; SPTR: S6 modification enzyme RimK; TIGRFAM: S6 modification enzyme RimK; IMG reference gene:2504122986; PFAM: RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family YP_004256350.1 COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; HAMAP: 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; GTP cyclohydrolase II, RibA; Riboflavin biosynthesis protein RibBA; InterPro IPR000422:IPR000926:IPR016299; KEGG: dra:DR_0155 GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; GTP cyclohydrolase II, RibA; SPTR: Riboflavin biosynthesis protein ribBA; TIGRFAM: GTP cyclohydrolase II, RibA; 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; IMG reference gene:2504122987; PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004256351.1 COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: ddr:Deide_02260 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Putative Riboflavin synthase alpha chain; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504122988; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit YP_004256352.1 COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR002125:IPR002734; KEGG: dra:DR_0153 riboflavin-specific deaminase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; CMP/dCMP deaminase, zinc-binding; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase., 5-amino-6-(5-phosphoribosylamino)uracil reductase; SPTR: Riboflavin-specific deaminase; TIGRFAM: Riboflavin biosynthesis protein RibD; manually curated; IMG reference gene:2504122989; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD YP_004256353.1 COGs: COG1859 RNA:NAD 2'-phosphotransferase; HAMAP: 2'-phosphotransferase KptA, putative; InterPro IPR002745:IPR022928; KEGG: ddr:Deide_02300 putative phosphotransferase KptA/Tpt1; probable RNA 2-phosphotransferase; PFAM: Phosphotransferase KptA/Tpt1; SPTR: Probable RNA 2'-phosphotransferase; IMG reference gene:2504122990; PFAM: RNA 2'-phosphotransferase, Tpt1 / KptA family YP_004256354.1 COGs: COG2810 type IV restriction endonuclease; InterPro IPR007409; KEGG: dge:Dgeo_0296 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Type IV restriction endonuclease; IMG reference gene:2504122991 YP_004256355.1 COGs: COG0192 S-adenosylmethionine synthetase; HAMAP: S-adenosylmethionine synthetase; InterPro IPR002133:IPR022628:IPR022629:IPR022630; KEGG: dra:DR_0640 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal; PRIAM: Methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase; IMG reference gene:2504122992; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_004256356.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR000836; KEGG: dge:Dgeo_0847 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2504122993; PFAM: Phosphoribosyl transferase domain YP_004256357.1 KEGG: ddr:Deide_15311 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122994 YP_004256358.1 KEGG: ddr:Deide_02990 putative radiation-induced protein; SPTR: Putative radiation-induced protein; IMG reference gene:2504122995 YP_004256359.1 COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198; KEGG: dge:Dgeo_0970 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504122996; PFAM: short chain dehydrogenase YP_004256360.1 COGs: COG4448 L-asparaginase II; InterPro IPR010349; KEGG: ddr:Deide_04400 putative L-asparaginase II; PFAM: L-asparaginase II; SPTR: Putative L-asparaginase II; IMG reference gene:2504122997; PFAM: L-asparaginase II YP_004256361.1 SPTR: Whole genome shotgun sequence assembly, contig_3085; IMG reference gene:2504122998; PFAM: Protein of unknown function (DUF2283) YP_004256362.1 COGs: COG1164 Oligoendopeptidase F; InterPro IPR001567; KEGG: dra:DR_A0206 oligoendopeptidase F, putative; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; SPTR: Oligoendopeptidase F, putative; IMG reference gene:2504122999; PFAM: Peptidase family M3; TIGRFAM: oligoendopeptidase, M3 family YP_004256363.1 InterPro IPR004843; KEGG: dra:DR_2331 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123000 YP_004256364.1 COGs: COG1230 Co/Zn/Cd efflux system component; InterPro IPR002524; KEGG: dge:Dgeo_0215 cation diffusion facilitator family transporter; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; IMG reference gene:2504123001; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004256365.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: dra:DR_1938 short chain dehydrogenase/reductase family oxidoreductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Oxidoreductase, short-chain dehydrogenase/reductase family; IMG reference gene:2504123002; PFAM: short chain dehydrogenase YP_004256366.1 KEGG: azl:AZL_b03320 serine 3-dehydrogenase; SPTR: Serine 3-dehydrogenase; IMG reference gene:2504123003 YP_004256367.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: ddr:Deide_21710 putative DNA-directed DNA polymerase (DNA polymerase III, subunit); SPTR: Putative DNA-directed DNA polymerase (DNA polymerase III, subunit); IMG reference gene:2504123004 YP_004256368.1 InterPro IPR004360; KEGG: asa:ASA_3354 glyoxalase family protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase family protein; IMG reference gene:2504123005; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004256369.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: dge:Dgeo_2261 beta-lactamase-like protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Beta-lactamase-like protein; IMG reference gene:2504123006; PFAM: Metallo-beta-lactamase superfamily YP_004256370.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: dra:DR_2557 hypothetical protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504123007; PFAM: Metallo-beta-lactamase superfamily YP_004256371.1 KEGG: pla:Plav_1571 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); IMG reference gene:2504123008 YP_004256372.1 COGs: COG5530 integral membrane protein; InterPro IPR014470; KEGG: dra:DR_0106 hypothetical protein; PFAM: Uncharacterised conserved protein UCP01500; SPTR: Putative uncharacterized protein; IMG reference gene:2504123009; PFAM: Predicted integral membrane protein (DUF2270) YP_004256373.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; InterPro IPR004424:IPR006204:IPR013750; KEGG: dra:DR_2605 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase, C-terminal; PRIAM: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; SPTR: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; IMG reference gene:2504123010; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004256374.1 InterPro IPR002716; KEGG: cyn:Cyan7425_3456 PilT protein domain protein; PFAM: PilT protein, N-terminal; SPTR: PilT protein domain protein; IMG reference gene:2504123011; PFAM: PIN domain YP_004256375.1 InterPro IPR006339:IPR007159; KEGG: msv:Mesil_3283 hypothetical protein; PFAM: Transcription regulator AbrB/SpoV, predicted; SMART: Transcription regulator AbrB/SpoV, predicted; SPTR: Putative uncharacterized protein; TIGRFAM: Transcription regulator AbrB; IMG reference gene:2504123012; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family YP_004256376.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; InterPro IPR001228; KEGG: dra:DR_2604 hypothetical protein; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; IMG reference gene:2504123013; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004256377.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: dra:DR_1534 acetyltransferase, putative; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Acetyltransferase, putative; IMG reference gene:2504123014; PFAM: Acetyltransferase (GNAT) family YP_004256378.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: dra:DR_0475 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein, EF-3 family; IMG reference gene:2504123015; PFAM: ABC transporter YP_004256379.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: dra:DR_0475 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein, EF-3 family; IMG reference gene:2504123016; PFAM: ABC transporter YP_004256380.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: bcg:BCG9842_B2962 proline iminopeptidase; PFAM: Alpha/beta hydrolase fold-1; SPTR: Proline iminopeptidase; IMG reference gene:2504123017; PFAM: alpha/beta hydrolase fold; TIGRFAM: proline-specific peptidases, Bacillus coagulans-type subfamily YP_004256381.1 COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR004507:IPR013121:IPR003382; KEGG: dra:DR_2603 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; Ferric reductase, NAD binding; SPTR: Probable aromatic acid decarboxylase; TIGRFAM: Phenylacrylic acid decarboxylase; IMG reference gene:2504123018; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases YP_004256382.1 COGs: COG2317 Zn-dependent carboxypeptidase; InterPro IPR001333; KEGG: dra:DR_2423 carboxypeptidase; PFAM: Peptidase M32, carboxypeptidase Taq metallopeptidase; PRIAM: Carboxypeptidase Taq; SPTR: Carboxypeptidase; IMG reference gene:2504123019; PFAM: Carboxypeptidase Taq (M32) metallopeptidase YP_004256383.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dra:DR_0395 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative uncharacterized protein; IMG reference gene:2504123020; PFAM: Major Facilitator Superfamily YP_004256384.1 COGs: COG0825 Acetyl-CoA carboxylase alpha subunit; HAMAP: Acetyl-CoA carboxylase, alpha subunit; InterPro IPR001095; KEGG: dra:DR_1214 acetyl-CoA carboxylase carboxyltransferase subunit alpha; PFAM: Acetyl-CoA carboxylase, alpha subunit; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; TIGRFAM: Acetyl-CoA carboxylase, alpha subunit; IMG reference gene:2504123021; PFAM: Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit YP_004256385.1 COGs: COG0777 Acetyl-CoA carboxylase beta subunit; HAMAP: Acetyl-CoA carboxylase carboxyl transferase, beta subunit; InterPro IPR000438:IPR000022; KEGG: ddr:Deide_01710 putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; (ACCase beta chain); PFAM: Carboxyl transferase; PRIAM: Acetyl-CoA carboxylase; SPTR: Putative Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; (ACCase beta chain); TIGRFAM: Acetyl-CoA carboxylase carboxyl transferase, beta subunit; IMG reference gene:2504123022; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit YP_004256386.1 COGs: COG0213 Thymidine phosphorylase; InterPro IPR018090:IPR017459:IPR000312:IPR013102; KEGG: dge:Dgeo_2180 pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase, family 3; Glycosyl transferase, family 3, N-terminal; Pyrimidine nucleoside phosphorylase, C-terminal; PRIAM: Pyrimidine-nucleoside phosphorylase; SMART: Pyrimidine nucleoside phosphorylase, C-terminal; SPTR: Pyrimidine-nucleoside phosphorylase; TIGRFAM: Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic; IMG reference gene:2504123023; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase YP_004256387.1 InterPro IPR000182; KEGG: ddr:Deide_08461 putative acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acetyltransferase; IMG reference gene:2504123024; PFAM: Acetyltransferase (GNAT) family YP_004256388.1 COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: dge:Dgeo_2164 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase superfamily; IMG reference gene:2504123025; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_004256389.1 COGs: COG0824 thioesterase; InterPro IPR006683; KEGG: dge:Dgeo_0244 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase superfamily; IMG reference gene:2504123026; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004256390.1 KEGG: ddr:Deide_01040 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123027 YP_004256391.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: ddr:Deide_01230 putative aminopeptidase, (heat stable aminopeptidase); PFAM: Peptidase M29, aminopeptidase II; SPTR: Putative Aminopeptidase, (Heat stable aminopeptidase); IMG reference gene:2504123028; PFAM: Thermophilic metalloprotease (M29) YP_004256392.1 KEGG: dra:DR_0569 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123029 YP_004256393.1 InterPro IPR008613; KEGG: mrb:Mrub_0594 Excalibur domain-containing protein; PFAM: Excalibur calcium-binding domain; SMART: Excalibur calcium-binding domain; SPTR: Excalibur domain protein; IMG reference gene:2504123031; PFAM: Excalibur calcium-binding domain YP_004256394.1 KEGG: rcu:RCOM_1791230 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123032 YP_004256395.1 KEGG: dra:DR_1881 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123033 YP_004256396.1 KEGG: dra:DR_1882 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123034 YP_004256397.1 KEGG: bgl:bglu_2g06500 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123035 YP_004256398.1 COGs: COG2258 conserved hypothetical protein; InterPro IPR005302; KEGG: dra:DR_1883 hypothetical protein; PFAM: Molybdenum cofactor sulfurase, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504123036; PFAM: MOSC domain YP_004256399.1 COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: dge:Dgeo_1423 fibronectin-binding A-like protein; PFAM: Domain of unknown function DUF814; Fibronectin-binding A, N-terminal; SPTR: Fibronectin-binding A-like protein; IMG reference gene:2504123037; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA) YP_004256400.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: ddr:Deide_08200 putative surface antigen precursor, outer membrane protein OMP85 family; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Putative Surface antigen, outer membrane protein OMP85 family; IMG reference gene:2504123038; PFAM: Surface antigen variable number repeat; Surface antigen; POTRA domain, ShlB-type YP_004256401.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037; KEGG: dge:Dgeo_1390 citrate transporter; PFAM: Divalent ion symporter; Regulator of K+ conductance, C-terminal; SPTR: Citrate transporter; IMG reference gene:2504123039; PFAM: Citrate transporter; TrkA-C domain YP_004256402.1 KEGG: ddr:Deide_17950 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123040 YP_004256403.1 InterPro IPR014833:IPR014832; KEGG: asa:ASA_1042 hypothetical protein; PFAM: TnsA endonuclease, N-terminal; TnsA endonuclease C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504123042; PFAM: TnsA endonuclease N terminal YP_004256404.1 KEGG: pca:Pcar_0125 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123043; PFAM: Mu transposase, C-terminal; Integrase core domain YP_004256405.1 KEGG: tcx:Tcr_1645 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504123047 YP_004256406.1 KEGG: mja:MJECS01 hypothetical protein; SPTR: Uncharacterized protein MJECS01; IMG reference gene:2504123048 YP_004256407.1 KEGG: acp:A2cp1_4002 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123049; PFAM: Type III restriction enzyme, res subunit YP_004256408.1 COGs: COG2189 Adenine specific DNA methylase Mod; InterPro IPR002941; KEGG: afn:Acfer_1215 site-specific DNA-methyltransferase (adenine-specific); PFAM: DNA methylase N-4/N-6; SPTR: Site-specific DNA-methyltransferase; manually curated; IMG reference gene:2504123050; PFAM: DNA methylase YP_004256409.1 IMG reference gene:2504123051 YP_004256410.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR006200:IPR019759; KEGG: ddr:Deide_1p01870 putative repressor LexA; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Putative repressor lexA; TIGRFAM: Peptidase S24, LexA repressor; IMG reference gene:2504123052; PFAM: Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_004256411.1 KEGG: abm:ABSDF3320 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123053 YP_004256412.1 COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482:IPR000523:IPR003593; KEGG: dra:DR_1656 Mg(2+) chelatase family protein; PFAM: Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Mg(2+) chelatase family protein; TIGRFAM: Mg chelatase-related protein; IMG reference gene:2504123054; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein YP_004256413.1 COGs: COG1826 Sec-independent protein secretion pathway components; HAMAP: Twin-arginine translocation protein TatA/E; InterPro IPR006312:IPR003369; KEGG: dra:DR_0292 hypothetical protein; PFAM: Bacterial sec-independent translocation protein MttA/Hcf106; SPTR: Putative uncharacterized protein; TIGRFAM: Twin-arginine translocation protein TatA/E; IMG reference gene:2504123055; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004256414.1 COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR006076; KEGG: dge:Dgeo_1398 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; IMG reference gene:2504123056; PFAM: FAD dependent oxidoreductase YP_004256415.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dge:Dgeo_0175 histone-like protein DNA-binding protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone-like protein DNA-binding protein; IMG reference gene:2504123057; PFAM: Bacterial DNA-binding protein YP_004256416.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: dge:Dgeo_0176 UBA/ThiF-type NAD/FAD binding fold; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: UBA/THIF-type NAD/FAD binding fold; IMG reference gene:2504123058; PFAM: MoeZ/MoeB domain; ThiF family YP_004256417.1 COGs: COG0344 membrane protein; InterPro IPR003811; KEGG: dra:DR_2270 membrane protein; PFAM: Glycerol-3-phosphate acyltransferase, bacteria; SPTR: Glycerol-3-phosphate acyltransferase 2; IMG reference gene:2504123059; PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase YP_004256418.1 KEGG: dge:Dgeo_0178 tetratricopeptide TPR_2; SPTR: Tetratricopeptide TPR_2; IMG reference gene:2504123060 YP_004256419.1 KEGG: dge:Dgeo_0179 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123061 YP_004256420.1 COGs: COG2389 Uncharacterized metal-binding protein; InterPro IPR019250; KEGG: dge:Dgeo_1187 hypothetical protein; PFAM: Protein of unknown function DUF2227, metal-binding; SPTR: Predicted membrane-bound metal-dependent hydrolase; IMG reference gene:2504123062; PFAM: Uncharacterized metal-binding protein (DUF2227) YP_004256421.1 COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005273:IPR005122; KEGG: dge:Dgeo_1556 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like; SPTR: Uracil-DNA glycosylase; TIGRFAM: Phage SPO1 DNA polymerase-related protein; IMG reference gene:2504123063; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4 YP_004256422.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR018392:IPR000064:IPR002482; KEGG: dra:DR_1749 endopeptidase-related protein; PFAM: NLP/P60; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Endopeptidase-related protein; IMG reference gene:2504123064; PFAM: NlpC/P60 family; LysM domain YP_004256423.1 InterPro IPR000620; KEGG: dge:Dgeo_1301 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504123065; PFAM: EamA-like transporter family YP_004256424.1 InterPro IPR001647; KEGG: dra:DR_1081 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504123066; PFAM: Bacterial regulatory proteins, tetR family YP_004256425.1 COGs: COG1544 Ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: dge:Dgeo_1384 sigma 54 modulation protein/ribosomal protein S30EA; PFAM: Ribosomal protein S30Ae/sigma 54 modulation protein; SPTR: Sigma 54 modulation protein/ribosomal protein S30EA; TIGRFAM: Ribosomal protein S30Ae/sigma 54 modulation protein; IMG reference gene:2504123067; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_004256426.1 COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR005148:IPR015945:IPR008909; KEGG: dge:Dgeo_1036 arginyl-tRNA synthetase; PFAM: DALR anticodon binding; Arginyl tRNA synthetase, class Ic, N-terminal; Arginyl-tRNA synthetase, class Ic, core; PRIAM: Arginine--tRNA ligase; SMART: DALR anticodon binding; SPTR: Arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; IMG reference gene:2504123068; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase YP_004256427.1 KEGG: ami:Amir_2512 VWA containing CoxE family protein; SPTR: VWA containing CoxE family protein; IMG reference gene:2504123069 YP_004256428.1 KEGG: dra:DR_1714 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123070 YP_004256429.1 COGs: COG1768 phosphohydrolase; InterPro IPR004843; KEGG: dge:Dgeo_1434 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; IMG reference gene:2504123071; PFAM: Calcineurin-like phosphoesterase YP_004256430.1 KEGG: dra:DR_1840 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123072 YP_004256431.1 COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170; KEGG: ddr:Deide_13020 putative phosphate uptake regulator, PhoU; PFAM: PhoU; SPTR: Putative Phosphate uptake regulator, PhoU; IMG reference gene:2504123073; PFAM: PhoU domain YP_004256432.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; KEGG: ddr:Deide_21120 putative 2-nitropropane dioxygenase; SPTR: Putative 2-Nitropropane dioxygenase; IMG reference gene:2504123074; PFAM: 2-nitropropane dioxygenase YP_004256433.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR005670:IPR003439:IPR003593; KEGG: dge:Dgeo_0652 phosphate ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Phosphate import ATP-binding protein pstB; TIGRFAM: Phosphate transport system permease protein 1; IMG reference gene:2504123075; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_004256434.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR005672:IPR000515; KEGG: ddr:Deide_2p01900 putative phosphate ABC transporter, permease component, PstA; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Putative phosphate ABC transporter, permease component, PstA; TIGRFAM: Phosphate transport system permease protein 2; IMG reference gene:2504123076; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA YP_004256435.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864:IPR000515; KEGG: ddr:Deide_2p01890 putative phosphate ABC transporter, permease component, PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Putative phosphate ABC transporter, permease component, PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; IMG reference gene:2504123077; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC YP_004256436.1 KEGG: mjl:Mjls_2717 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123078 YP_004256437.1 KEGG: cyb:CYB_0484 type IV pilus secretin PilQ, putative; SPTR: Type IV pilus secretin PilQ, putative; IMG reference gene:2504123079 YP_004256438.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR005673:IPR006059; KEGG: dge:Dgeo_0649 periplasmic phosphate binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: ABC-type phosphate transport system, periplasmic component, PstS; TIGRFAM: Periplasmic phosphate binding protein; IMG reference gene:2504123080; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate ABC transporter, phosphate-binding protein YP_004256439.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: dra:DR_0110 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: UPF0135 protein DR_0110; TIGRFAM: NGG1p interacting factor 3, NIF3; IMG reference gene:2504123081; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family YP_004256440.1 COGs: COG0125 Thymidylate kinase; HAMAP: Thymidylate kinase; InterPro IPR018094; KEGG: dra:DR_0111 thymidylate kinase; PFAM: Thymidylate kinase; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: Thymidylate kinase; IMG reference gene:2504123082; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_004256441.1 KEGG: npu:Npun_F4656 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123083 YP_004256442.1 COGs: COG3823 Glutamine cyclotransferase; InterPro IPR007788; KEGG: dge:Dgeo_1980 glutamine cyclotransferase; PFAM: Glutamine cyclotransferase; SPTR: Glutamine cyclotransferase; IMG reference gene:2504123084; PFAM: Glutamine cyclotransferase YP_004256443.1 KEGG: dge:Dgeo_0597 hypothetical protein; SPTR: Pre-peptidace domain-containing protein; IMG reference gene:2504123085 YP_004256444.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dge:Dgeo_0381 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC-type transport system, ATPase component; IMG reference gene:2504123086; PFAM: ABC transporter YP_004256445.1 KEGG: dge:Dgeo_0382 hypothetical protein; SPTR: ABC-type transport system, permease component; IMG reference gene:2504123087 YP_004256446.1 KEGG: dge:Dgeo_0384 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123088 YP_004256447.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: reh:H16_A1144 hydrolase or acyltransferase; PFAM: Alpha/beta hydrolase fold-1; SPTR: Predicted hydrolase or acyltransferase; IMG reference gene:2504123089; PFAM: alpha/beta hydrolase fold YP_004256448.1 InterPro IPR001450; KEGG: dge:Dgeo_0388 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; IMG reference gene:2504123090; PFAM: 4Fe-4S binding domain YP_004256449.1 KEGG: ttj:TTHA1701 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123091 YP_004256450.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442:IPR002290:IPR020635; KEGG: dge:Dgeo_0168 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase; IMG reference gene:2504123092; PFAM: Protein kinase domain YP_004256451.1 KEGG: afw:Anae109_4212 LigA; SPTR: Peptide chain release factor 2; manually curated; IMG reference gene:2504123093; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_004256452.1 InterPro IPR005358; KEGG: ddr:Deide_02401 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein; IMG reference gene:2504123094 YP_004256453.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: dra:DR_2461 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; IMG reference gene:2504123095; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_004256454.1 KEGG: dge:Dgeo_0116 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123096 YP_004256455.1 COGs: COG5637 integral membrane protein; InterPro IPR005031; KEGG: dra:DR_2377 hypothetical protein; PFAM: Streptomyces cyclase/dehydrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123097; PFAM: Polyketide cyclase / dehydrase and lipid transport YP_004256456.1 InterPro IPR000620; KEGG: dge:Dgeo_0112 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Permease DMT superfamily; IMG reference gene:2504123098; PFAM: EamA-like transporter family YP_004256457.1 KEGG: tpr:Tpau_4129 cobalt transport protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123099 YP_004256458.1 COGs: COG2361 conserved hypothetical protein; InterPro IPR002934:IPR008201; KEGG: dra:DR_0248 hypothetical protein; PFAM: Protein of unknown function DUF86; Nucleotidyl transferase domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504123100; PFAM: Protein of unknown function DUF86; Nucleotidyltransferase domain YP_004256459.1 KEGG: tpr:Tpau_1602 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123101 YP_004256460.1 InterPro IPR004942; KEGG: dra:DR_2347 hypothetical protein; PFAM: Dynein light chain-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504123102 YP_004256461.1 KEGG: dge:Dgeo_0055 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123103 YP_004256462.1 COGs: COG0459 Chaperonin GroEL (HSP60 family); HAMAP: Chaperonin Cpn60; InterPro IPR001844:IPR002423; KEGG: ddr:Deide_22590 chaperonin GroEL; PFAM: Chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: Chaperonin Cpn60; IMG reference gene:2504123104; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004256463.1 COGs: COG0234 Co-chaperonin GroES (HSP10); HAMAP: Chaperonin Cpn10; InterPro IPR020818; KEGG: ddr:Deide_22580 co-chaperonin GroES; PFAM: Chaperonin Cpn10; SMART: Chaperonin Cpn10; SPTR: 10 kDa chaperonin; IMG reference gene:2504123105; PFAM: Chaperonin 10 Kd subunit YP_004256464.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dra:DR_0605 GGDEF family protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF family protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504123106; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004256465.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: hau:Haur_2942 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504123107; PFAM: Acetyltransferase (GNAT) family YP_004256466.1 KEGG: cpi:Cpin_1550 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123108 YP_004256467.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; HAMAP: Formylmethionine deformylase; InterPro IPR000181; KEGG: dra:DR_2434 peptide deformylase; PFAM: Formylmethionine deformylase; PRIAM: Peptide deformylase; SPTR: Peptide deformylase; TIGRFAM: Formylmethionine deformylase; IMG reference gene:2504123109; PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_004256468.1 COGs: COG0223 Methionyl-tRNA formyltransferase; HAMAP: Methionyl-tRNA formyltransferase; InterPro IPR005794:IPR002376:IPR005793; KEGG: dra:DR_2435 methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; Formyl transferase, C-terminal; PRIAM: Methionyl-tRNA formyltransferase; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: Methionyl-tRNA formyltransferase; IMG reference gene:2504123110; PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_004256469.1 KEGG: ddr:Deide_23080 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123111 YP_004256470.1 KEGG: art:Arth_0856 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123112 YP_004256471.1 COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265:IPR003651; KEGG: ddr:Deide_23070 putative DNA-(apurinic or apyrimidinic site) lyase (endonuclease, deoxyribonuclease); PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SMART: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SPTR: Putative DNA-(Apurinic or apyrimidinic site) lyase (Endonuclease, deoxyribonuclease); IMG reference gene:2504123113; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004256472.1 KEGG: xla:397995 middle molecular weight neurofilament protein NF-M(2); SPTR: Internalin protein; IMG reference gene:2504123114 YP_004256473.1 KEGG: ddr:Deide_23280 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123115 YP_004256474.1 IMG reference gene:2504123116 YP_004256475.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: aap:NT05HA_1304 aminotransferase, class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Histidinol-phosphate transaminase; SPTR: Aminotransferase, class I and II; IMG reference gene:2504123118; PFAM: Aminotransferase class I and II YP_004256476.1 KEGG: dra:DR_2541 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123119 YP_004256477.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: dra:DR_2362 transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator; IMG reference gene:2504123120; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_004256478.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: ddr:Deide_22880 putative acyl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA dehydrogenase, N-terminal; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Putative acyl-CoA dehydrogenase; IMG reference gene:2504123121; PFAM: Acyl-CoA dehydrogenase N terminal; Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004256479.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523; KEGG: dra:DR_2463 transport protein, putative; PFAM: Mg2+ transporter protein, CorA-like; SPTR: Transport protein, putative; IMG reference gene:2504123122; PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA) YP_004256480.1 KEGG: ddr:Deide_22320 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123123; PFAM: Protein of unknown function (DUF3105) YP_004256481.1 COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: dge:Dgeo_2332 VanW; PFAM: Vancomycin resistance VanW; SPTR: VanW-like protein; IMG reference gene:2504123124; PFAM: VanW like protein YP_004256482.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027; KEGG: ddr:Deide_23360 putative thioredoxin reductase, putative pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative Thioredoxin reductase, putative Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504123125; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: putative bacillithiol system thiol disulfide oxidoreductase, YpdA family YP_004256483.1 KEGG: rpc:RPC_2368 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123126 YP_004256484.1 COGs: COG1476 transcriptional regulator protein; InterPro IPR001387; KEGG: tra:Trad_2497 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504123127; PFAM: Helix-turn-helix YP_004256485.1 COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR006076; KEGG: ddr:Deide_2p01220 putative FAD dependent oxidoreductase, putative phytoene dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: Putative FAD dependent oxidoreductase, putative phytoene dehydrogenase; IMG reference gene:2504123128; PFAM: FAD dependent oxidoreductase YP_004256486.1 COGs: COG2324 membrane protein; InterPro IPR017825:IPR007354; KEGG: ddr:Deide_2p01210 hypothetical protein; putative membrane protein; PFAM: Protein of unknown function DUF422; SPTR: Putative uncharacterized protein; TIGRFAM: Lycopene cyclase domain; IMG reference gene:2504123129; PFAM: Protein of unknown function (DUF422); TIGRFAM: lycopene cyclase domain YP_004256487.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: ddr:Deide_2p01205 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123130; PFAM: Acyltransferase YP_004256488.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: dge:Dgeo_2307 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, family 2; IMG reference gene:2504123131; PFAM: Glycosyl transferase family 2 YP_004256489.1 COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR002937; KEGG: dra:DR_2250 methoxyneurosporene dehydrogenase; PFAM: Amine oxidase; SPTR: Methoxyneurosporene dehydrogenase; IMG reference gene:2504123132; PFAM: Flavin containing amine oxidoreductase YP_004256490.1 KEGG: smt:Smal_3165 integral membrane sensor signal transduction histidine kinase; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504123133 YP_004256491.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dge:Dgeo_2307 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, family 2; IMG reference gene:2504123134; PFAM: Glycosyl transferase family 2 YP_004256492.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dra:DR_0799 glucose-fructose oxidoreductase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; PRIAM: Glucose-fructose oxidoreductase; SPTR: Glucose-fructose oxidoreductase; manually curated; IMG reference gene:2504123135; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain YP_004256493.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sti:Sthe_3460 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504123136; PFAM: ABC transporter YP_004256494.1 InterPro IPR003838; KEGG: dra:DR_A0279 hypothetical protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Putative uncharacterized protein; IMG reference gene:2504123137; PFAM: Predicted permease YP_004256495.1 COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: bha:BH0219 L-lactate permease; PFAM: L-lactate permease; SPTR: L-lactate permease; IMG reference gene:2504123138; PFAM: L-lactate permease YP_004256496.1 COGs: COG2374 extracellular nuclease; InterPro IPR005135:IPR000601:IPR022409; KEGG: ddr:Deide_09050 putative extracellular nuclease, endonuclease/exonuclease/phosphatase family; PFAM: Endonuclease/exonuclease/phosphatase; PKD domain; SMART: PKD/Chitinase domain; SPTR: Putative extracellular nuclease, Endonuclease/Exonuclease/phosphatase family; IMG reference gene:2504123139; PFAM: Endonuclease/Exonuclease/phosphatase family YP_004256497.1 COGs: COG0114 Fumarase; HAMAP: Fumarate hydratase, class II; InterPro IPR005677:IPR022761:IPR018951; KEGG: dra:DR_2627 fumarate hydratase; PFAM: Lyase 1, N-terminal; Fumarase C, C-terminal; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase class II; TIGRFAM: Fumarate hydratase, class II; IMG reference gene:2504123140; PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: fumarate hydratase, class II YP_004256498.1 KEGG: axy:AXYL_06047 calcineurin-like phosphoesterase family protein 9; SPTR: Ser/Thr protein phosphatase family protein; IMG reference gene:2504123141 YP_004256499.1 COGs: COG3544 conserved hypothetical protein; InterPro IPR005183; KEGG: dge:Dgeo_0086 hypothetical protein; PFAM: Domain of unknown function DUF305; SPTR: Putative uncharacterized protein; IMG reference gene:2504123142; PFAM: Domain of unknown function (DUF305) YP_004256500.1 KEGG: bcm:Bcenmc03_0751 beta-ketoacyl synthase; SPTR: Beta-ketoacyl synthase; IMG reference gene:2504123143 YP_004256501.1 COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: dge:Dgeo_0032 ribonuclease II; PFAM: Ribonuclease II/R; SMART: Ribonuclease II/R; SPTR: Ribonuclease II, VacB-like protein; IMG reference gene:2504123144; PFAM: RNB domain YP_004256502.1 KEGG: dra:DR_0021 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123145 YP_004256503.1 KEGG: dra:DR_0082 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123146 YP_004256504.1 COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR006255:IPR000089:IPR004167:IPR001078; KEGG: dge:Dgeo_0139 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; PRIAM: Dihydrolipoyllysine-residue succinyltransferase; SPTR: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; TIGRFAM: Dihydrolipoamide succinyltransferase; IMG reference gene:2504123147; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component) YP_004256505.1 COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR011603:IPR001017:IPR005475; KEGG: dge:Dgeo_0140 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; PRIAM: Oxoglutarate dehydrogenase (succinyl-transferring); SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; manually curated; IMG reference gene:2504123148; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component YP_004256506.1 KEGG: dge:Dgeo_0142 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123149 YP_004256507.1 COGs: COG3386 Gluconolactonase; InterPro IPR013658; KEGG: ddr:Deide_21410 putative gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region; SPTR: Putative Gluconolactonase; IMG reference gene:2504123150; PFAM: SMP-30/Gluconolaconase/LRE-like region YP_004256508.1 COGs: COG0207 Thymidylate synthase; HAMAP: Thymidylate synthase; InterPro IPR000398; KEGG: dra:DR_2630 thymidylate synthase; PFAM: Thymidylate synthase; PRIAM: Thymidylate synthase; SPTR: Thymidylate synthase; TIGRFAM: Thymidylate synthase; IMG reference gene:2504123151; PFAM: Thymidylate synthase; TIGRFAM: thymidylate synthase YP_004256509.1 COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125; KEGG: dra:DR_2631 deoxycytidylate deaminase, putative; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: Deoxycytidylate deaminase, putative; IMG reference gene:2504123152; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004256510.1 COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796; KEGG: ddr:Deide_23020 putative dihydrofolate reductase (tetrahydrofolate dehydrogenase); PFAM: Dihydrofolate reductase domain; PRIAM: Dihydrofolate reductase; SPTR: Putative dihydrofolate reductase (Tetrahydrofolate dehydrogenase); IMG reference gene:2504123153; PFAM: Dihydrofolate reductase YP_004256511.1 KEGG: ach:Achl_2916 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123154 YP_004256512.1 KEGG: sco:SCO0976 hypothetical protein; SPTR: Putative uncharacterized protein SCO0976; IMG reference gene:2504123155 YP_004256513.1 COGs: COG1393 Arsenate reductase and related protein glutaredoxin family; InterPro IPR006660; KEGG: dra:DR_0136 hypothetical protein; PFAM: Arsenate reductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504123157; PFAM: ArsC family YP_004256514.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; HAMAP: DNA helicase, Holliday junction RuvB type; InterProIPR004605:IPR008824:IPR003959:IPR008823:IPR 003593; KEGG: dra:DR_0596 Holliday junction DNA helicase RuvB; PFAM: DNA helicase, Holliday junction RuvB type, C-terminal; ATPase, AAA-type, core; DNA helicase, Holliday junction RuvB type, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: DNA helicase, Holliday junction RuvB type; IMG reference gene:2504123158; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_004256515.1 InterPro IPR018966; KEGG: chl:Chy400_4161 hypothetical protein; PFAM: VTC domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504123159; PFAM: VTC domain YP_004256516.1 KEGG: dal:Dalk_4019 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123160 YP_004256517.1 COGs: COG1999 Uncharacterized protein SCO1/SenC/PrrC involved in biogenesis of respiratory and photosynthetic systems; InterPro IPR003782; KEGG: dge:Dgeo_0405 electron transport protein SCO1/SenC; PFAM: Copper chaperone SCO1/SenC; SPTR: Electron transport protein SCO1/SenC; IMG reference gene:2504123161; PFAM: SCO1/SenC YP_004256518.1 COGs: COG0843 Heme/copper-type cytochrome/quinol oxidase subunit 1; InterPro IPR000883:IPR000298; KEGG: dra:DR_2620 cytochrome c oxidase, subunit I; PFAM: Cytochrome c oxidase, subunit I; Cytochrome c oxidase, subunit III; SPTR: Cytochrome c oxidase, subunit I; IMG reference gene:2504123162; PFAM: Cytochrome c oxidase subunit III; Cytochrome C and Quinol oxidase polypeptide I YP_004256519.1 COGs: COG1622 Heme/copper-type cytochrome/quinol oxidase subunit 2; InterPro IPR014222:IPR011759:IPR002429:IPR003088; KEGG: dge:Dgeo_0407 cytochrome c oxidase, subunit II; PFAM: Cytochrome c oxidase subunit II C-terminal; Cytochrome C oxidase subunit II, transmembrane domain; Cytochrome c, class I; SPTR: Cytochrome c oxidase subunit 2; TIGRFAM: Cytochrome c oxidase, subunit II; IMG reference gene:2504123163; PFAM: Cytochrome c; Cytochrome C oxidase subunit II, periplasmic domain; Cytochrome C oxidase subunit II, transmembrane domain; TIGRFAM: cytochrome c oxidase, subunit II YP_004256520.1 COGs: COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor); HAMAP: Protohaem IX farnesyltransferase; InterPro IPR006369:IPR000537; KEGG: dra:DR_2618 protoheme IX farnesyltransferase; PFAM: UbiA prenyltransferase; SPTR: Protoheme IX farnesyltransferase; TIGRFAM: Protohaem IX farnesyltransferase; IMG reference gene:2504123164; PFAM: UbiA prenyltransferase family; TIGRFAM: protoheme IX farnesyltransferase YP_004256521.1 COGs: COG1612 Uncharacterized protein required for cytochrome oxidase assembly; InterPro IPR003780; KEGG: dge:Dgeo_0409 cytochrome oxidase assembly; PFAM: Heme A synthase/Protoheme IX farnesyltransferase; SPTR: Cytochrome oxidase assembly protein, CtaA; IMG reference gene:2504123165; PFAM: Cytochrome oxidase assembly protein YP_004256522.1 COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: ddr:Deide_04170 putative aminodeoxychorismate lyase precursor; PFAM: Uncharacterised protein family UPF0755; SPTR: Putative Aminodeoxychorismate lyase; TIGRFAM: Uncharacterised protein family UPF0755; IMG reference gene:2504123166; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family YP_004256523.1 COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129:IPR003593; KEGG: dge:Dgeo_1322 arginine/ornithine transport system ATPase; PFAM: ArgK protein; SMART: ATPase, AAA+ type, core; SPTR: LAO/AO transport system ATPase; TIGRFAM: ArgK protein; IMG reference gene:2504123170; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase YP_004256524.1 COGs: COG1015 Phosphopentomutase; InterPro IPR010045:IPR006124; KEGG: dge:Dgeo_0586 phosphopentomutase; PFAM: Metalloenzyme; PRIAM: Phosphopentomutase; SPTR: Phosphopentomutase; TIGRFAM: Phosphopentomutase; IMG reference gene:2504123171; PFAM: Metalloenzyme superfamily; TIGRFAM: phosphopentomutase YP_004256525.1 KEGG: dra:DR_2136 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123172; PFAM: Protein of unknown function (DUF3108) YP_004256526.1 COGs: COG2322 membrane protein; InterPro IPR007352; KEGG: dge:Dgeo_0410 hypothetical protein; PFAM: Protein of unknown function DUF420; SPTR: Putative uncharacterized protein; IMG reference gene:2504123173; PFAM: Protein of unknown function (DUF420) YP_004256527.1 COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dra:DR_2134 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504123174; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004256528.1 COGs: COG4372 Uncharacterized protein with the myosin-like domain; KEGG: dge:Dgeo_0588 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123175; PFAM: Protein of unknown function (DUF3084) YP_004256529.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; HAMAP: Glucosamine-fructose-6-phosphate aminotransferase, isomerising; InterPro IPR005855:IPR000583:IPR001347; KEGG: dra:DR_0302 glucosamine--fructose-6-phosphate aminotransferase; PFAM: Glutamine amidotransferase, class-II; Sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glucosamine--fructose-6-phosphate aminotransferase (Isomerizing); TIGRFAM: Glucosamine-fructose-6-phosphate aminotransferase, isomerising; IMG reference gene:2504123176; PFAM: SIS domain; Glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing) YP_004256530.1 COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; HAMAP: Mannitol-1-phosphate 5-dehydrogenase; InterPro IPR013131:IPR013118:IPR023028; KEGG: tml:GSTUM_00011542001 hypothetical protein; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal; PRIAM: Mannitol-1-phosphate 5-dehydrogenase; SPTR: Whole genome shotgun sequence assembly, scaffold_87, strain Mel28; IMG reference gene:2504123177; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain YP_004256531.1 COGs: COG2213 Phosphotransferase system mannitol-specific IIBC component; InterPro IPR004718:IPR003352:IPR003501:IPR002178; KEGG: has:Halsa_1171 PTS system, mannitol-specific IIC subunit; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; Phosphotransferase system, EIIC; Phosphotransferase system, EIIB component, type 2/3; SPTR: PTS system, mannitol-specific IIABC component; TIGRFAM: Phosphotransferase system, mannitol-specific enzyme IIC; IMG reference gene:2504123178; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, mannitol-specific IIC component YP_004256532.1 COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: dge:Dgeo_0104 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Regulatory protein, FmdB, putative; IMG reference gene:2504123179; TIGRFAM: putative regulatory protein, FmdB family YP_004256533.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478; KEGG: dge:Dgeo_0103 peptidase S1 and S6, chymotrypsin/Hap; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: Peptidase S1 and S6, chymotrypsin/Hap; IMG reference gene:2504123180; PFAM: Trypsin YP_004256534.1 InterPro IPR006675:IPR006674; KEGG: dge:Dgeo_1575 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: Metal dependent phosphohydrolase; TIGRFAM: Uncharacterised protein family HDIG; IMG reference gene:2504123181; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004256535.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; HAMAP: N-acetylglucosaminyltransferase, MurG; InterPro IPR006009:IPR004276:IPR007235; KEGG: dge:Dgeo_1630 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: Glycosyl transferase, family 28, C-terminal; Glycosyl transferase, family 28; PRIAM: Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; SPTR:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; TIGRFAM: N-acetylglucosaminyltransferase, MurG; IMG reference gene:2504123182; PFAM: Glycosyltransferase family 28 N-terminal domain; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_004256536.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; HAMAP: UDP-N-acetylmuramate-alanine ligase; InterPro IPR005758:IPR000713:IPR013221:IPR004101; KEGG: ddr:Deide_14560 putative UDP-N-acetylmuramate--L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase); PFAM: Mur ligase, N-terminal; Mur ligase, central; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramate--L-alanine ligase; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate-alanine ligase; IMG reference gene:2504123183; PFAM: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase YP_004256537.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; HAMAP: UDP-N-acetylenolpyruvoylglucosamine reductase; InterPro IPR003170:IPR006094:IPR011601; KEGG: dra:DR_0628 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal; FAD linked oxidase, N-terminal; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; IMG reference gene:2504123184; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004256538.1 COGs: COG1589 Cell division septal protein; InterPro IPR013685; KEGG: dra:DR_0629 cell division protein FtsQ-related protein; PFAM: Polypeptide-transport-associated, FtsQ-type; SPTR: Cell division protein FtsQ-related protein; IMG reference gene:2504123185; PFAM: POTRA domain, FtsQ-type YP_004256539.1 COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR020823:IPR003494; KEGG: dge:Dgeo_1634 cell division protein FtsA; PFAM: Cell division protein FtsA domain; SMART: Cell division protein FtsA domain; SPTR: Cell division protein FtsA; TIGRFAM: Cell division protein family FtsA; IMG reference gene:2504123186; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA YP_004256540.1 COGs: COG0206 Cell division GTPase; InterPro IPR000158:IPR003008:IPR018316; KEGG: dge:Dgeo_1635 cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SMART: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: Cell division protein FtsZ, N-terminal; IMG reference gene:2504123187; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004256541.1 KEGG: dra:DR_0948 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123188 YP_004256542.1 COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: dra:DR_1958 ADP-ribosylglycohydrolase, putative; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylglycohydrolase, putative; IMG reference gene:2504123189; PFAM: ADP-ribosylglycohydrolase YP_004256543.1 COGs: COG0855 Polyphosphate kinase; HAMAP: Polyphosphate kinase; InterPro IPR003414; KEGG: dge:Dgeo_0438 polyphosphate kinase; PFAM: Polyphosphate kinase; PRIAM: Polyphosphate kinase; SPTR: Polyphosphate kinase; TIGRFAM: Polyphosphate kinase; IMG reference gene:2504123190; PFAM: Polyphosphate kinase; TIGRFAM: polyphosphate kinase 1 YP_004256544.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR017568:IPR014030:IPR014031:IPR020841; KEGG: ddr:Deide_05750 putative beta-ketoacyl-acyl-carrier-protein synthase I (3-oxoacyl-[acyl-carrier-protein] synthase); PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SMART: Polyketide synthase, beta-ketoacyl synthase domain; SPTR: Putative Beta-ketoacyl-acyl-carrier-protein synthase I (3-oxoacyl-[acyl-carrier-protein] synthase); TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; IMG reference gene:2504123191; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004256545.1 COGs: COG0236 Acyl carrier protein; HAMAP: Acyl carrier protein (ACP); InterPro IPR003231:IPR006163; KEGG: ddr:Deide_05740 acyl carrier protein; PFAM: Phosphopantetheine-binding; SPTR: Acyl carrier protein; TIGRFAM: Acyl carrier protein (ACP); IMG reference gene:2504123192; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_004256546.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR011284:IPR002198:IPR020842; KEGG: dra:DR_1943 3-oxoacyl-acyl carrier protein reductase; PFAM: Short-chain dehydrogenase/reductase SDR; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: 3-oxoacyl-acyl carrier protein reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; IMG reference gene:2504123193; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_004256547.1 COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043:IPR020801; KEGG: dge:Dgeo_0434 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2504123194; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase YP_004256548.1 COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); HAMAP: Beta-ketoacyl-acyl carrier protein synthase III (FabH); InterPro IPR004655:IPR013751:IPR013747; KEGG: dge:Dgeo_0433 3-oxoacyl-(acyl carrier protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase III; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 3; TIGRFAM: Beta-ketoacyl-acyl carrier protein synthase III (FabH); IMG reference gene:2504123195; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III YP_004256549.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); HAMAP: Trigger factor; InterPro IPR005215:IPR008881:IPR008880; KEGG: ddr:Deide_05690 putative trigger factor, TF; PFAM: Trigger factor, C-terminal, bacterial; Trigger factor, ribosome-binding, bacterial; SPTR: Trigger factor; TIGRFAM: Trigger factor; IMG reference gene:2504123196; PFAM: Bacterial trigger factor protein (TF) C-terminus; Bacterial trigger factor protein (TF); TIGRFAM: trigger factor YP_004256550.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR013767:IPR003661:IPR003594; KEGG: ddr:Deide_02740 putative histidine kinase, classic; PFAM: ATPase-like, ATP-binding domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Putative histidine kinase, classic; TIGRFAM: PAS; IMG reference gene:2504123199; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004256551.1 COGs: COG2311 membrane protein; InterPro IPR007349; KEGG: dge:Dgeo_2327 hypothetical protein; PFAM: Domain of unknown function DUF418; SPTR: Putative uncharacterized protein; IMG reference gene:2504123200; PFAM: Protein of unknown function (DUF418) YP_004256552.1 COGs: COG2327 conserved hypothetical protein; InterPro IPR019896:IPR007345; KEGG: ddr:Deide_00410 putative polysaccharide pyruvyl transferase; PFAM: Polysaccharide pyruvyl transferase; SPTR: Putative Polysaccharide pyruvyl transferase; TIGRFAM: Polysaccharide pyruvyl transferase, CsaB; IMG reference gene:2504123201; PFAM: Polysaccharide pyruvyl transferase; TIGRFAM: polysaccharide pyruvyl transferase CsaB YP_004256553.1 KEGG: dge:Dgeo_0201 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123202 YP_004256554.1 COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR011545:IPR001650:IPR018973:IPR014001; KEGG: dge:Dgeo_0390 DEAD/DEAH box helicase-like protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Protein of unknown function DUF1998; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase-like protein; IMG reference gene:2504123203; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase YP_004256555.1 COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170; KEGG: ddr:Deide_19820 putative phosphate transport system protein PhoU; PFAM: PhoU; SPTR: Putative phosphate transport system protein phoU; TIGRFAM: PhoU; IMG reference gene:2504123204; PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU YP_004256556.1 KEGG: ddr:Deide_23320 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123205 YP_004256557.1 KEGG: dge:Dgeo_2035 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123206 YP_004256558.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: ddr:Deide_04720 putative NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: Putative NUDIX hydrolase; IMG reference gene:2504123207; PFAM: NUDIX domain YP_004256559.1 COGs: COG0305 Replicative DNA helicase; InterProIPR007692:IPR006141:IPR007693:IPR007694:IPR 003587:IPR003586; KEGG: dge:Dgeo_2037 DnaB-like protein helicase; PFAM: DNA helicase, DnaB-like, N-terminal; DNA helicase, DnaB-like, C-terminal; SMART: Hedgehog/intein hint, N-terminal; Hedgehog/intein hint domain, C-terminal; SPTR: DnaB-like protein helicase; TIGRFAM: DNA helicase, DnaB type; Intein splice site; IMG reference gene:2504123208; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; intein N-terminal splicing region; intein C-terminal splicing region YP_004256560.1 InterPro IPR012902; KEGG: dra:DR_0548 pilin, type IV, putative; SPTR: Pilin, type IV, putative; IMG reference gene:2504123209; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004256561.1 InterPro IPR012902; KEGG: tra:Trad_0712 pilin, type IV, putative; SPTR: Pilin, type IV, putative; IMG reference gene:2504123210; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004256562.1 KEGG: psa:PST_1908 hypothetical protein; SPTR: Trap-type mannitol/chloroaromatic compound transport system, small permease component; IMG reference gene:2504123211 YP_004256563.1 KEGG: tra:Trad_0979 O-antigen polymerase; SPTR: O-antigen polymerase; IMG reference gene:2504123212; PFAM: O-Antigen ligase YP_004256564.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: dra:DR_2622 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; IMG reference gene:2504123213; PFAM: Methyltransferase domain YP_004256565.1 COGs: COG0240 Glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase, NAD-dependent; InterPro IPR011128:IPR006109:IPR006168; KEGG: dge:Dgeo_2043 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; IMG reference gene:2504123214; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YP_004256566.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR006402:IPR006439:IPR005834; KEGG: dge:Dgeo_1330 HAD family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2504123215; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004256567.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: dge:Dgeo_1329 histidine triad (HIT) protein; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; IMG reference gene:2504123216; PFAM: HIT domain YP_004256568.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198:IPR020842; KEGG: dra:DR_1620 ketoacyl reductase, putative; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Estradiol 17-beta-dehydrogenase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Ketoacyl reductase, putative; IMG reference gene:2504123217; PFAM: short chain dehydrogenase YP_004256569.1 KEGG: dge:Dgeo_0836 hypothetical protein; SPTR: Inorganic pyrophosphatase related protein; IMG reference gene:2504123218 YP_004256570.1 KEGG: dge:Dgeo_0837 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123219 YP_004256571.1 KEGG: rhi:NGR_c35100 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123220 YP_004256572.1 COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: dge:Dgeo_0838 16S ribosomal RNA methyltransferase RsmE; PFAM: Ribosomal RNA small subunit methyltransferase E; SPTR: Putative uncharacterized protein; TIGRFAM: Ribosomal RNA small subunit methyltransferase E; IMG reference gene:2504123221; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family YP_004256573.1 COGs: COG2264 Ribosomal protein L11 methylase; HAMAP: Ribosomal protein L11 methyltransferase; InterPro IPR010456:IPR004498; KEGG: ddr:Deide_13790 ribosomal protein L11 methyltransferase; PFAM: Ribosomal L11 methyltransferase, PrmA; SPTR: Ribosomal protein L11 methyltransferase; IMG reference gene:2504123222; PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase YP_004256574.1 InterPro IPR007899; KEGG: dra:DR_2614 hypothetical protein; PFAM: CHAD; SMART: CHAD; SPTR: Putative uncharacterized protein; IMG reference gene:2504123223; PFAM: CHAD domain YP_004256575.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073:IPR020802; KEGG: dge:Dgeo_1989 alpha/beta hydrolase fold; PFAM: Alpha/beta hydrolase fold-1; SMART: Polyketide synthase, thioesterase domain; SPTR: Alpha/beta hydrolase fold; IMG reference gene:2504123224; PFAM: Thioesterase domain YP_004256576.1 KEGG: rrs:RoseRS_0549 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123225 YP_004256577.1 COGs: COG1760 L-serine deaminase; InterPro IPR004642:IPR005130; KEGG: ddr:Deide_15210 putative L-serine ammonia-lyase (L-serine dehydratase)(L-serine deaminase); PFAM: Serine dehydratase-like, alpha subunit; PRIAM: L-serine ammonia-lyase; SPTR: Putative L-serine ammonia-lyase (L-serine dehydratase)(L-serine deaminase); TIGRFAM: Serine dehydratase, alpha subunit; IMG reference gene:2504123226; PFAM: Serine dehydratase alpha chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit YP_004256578.1 COGs: COG1760 L-serine deaminase; InterPro IPR004643:IPR005131:IPR002912; KEGG: dra:DR_0497 L-serine dehydratase, beta subunit; PFAM: Serine dehydratase beta chain; Amino acid-binding ACT; PRIAM: L-serine ammonia-lyase; SPTR: L-serine dehydratase, beta subunit; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase beta subunit; IMG reference gene:2504123227; PFAM: ACT domain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit YP_004256579.1 COGs: COG1381 Recombinational DNA repair protein (RecF pathway); HAMAP: Recombination protein O, RecO; InterPro IPR003717; KEGG: dge:Dgeo_0855 DNA repair protein RecO; PFAM: Recombination protein O, RecO; SPTR: DNA repair protein recO; TIGRFAM: Recombination protein O, RecO; IMG reference gene:2504123228; PFAM: Recombination protein O C terminal; Recombination protein O N terminal; TIGRFAM: DNA repair protein RecO YP_004256580.1 KEGG: ddr:Deide_13820 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123229 YP_004256581.1 KEGG: dra:DR_1925 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123230 YP_004256582.1 COGs: COG0506 Proline dehydrogenase; InterPro IPR002872; KEGG: dge:Dgeo_0851 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; IMG reference gene:2504123231; PFAM: Proline dehydrogenase YP_004256583.1 COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: gau:GAU_2960 hypothetical protein; PFAM: Uncharacterised protein family UPF0157; SPTR: Putative uncharacterized protein; IMG reference gene:2504123232; PFAM: Uncharacterised protein family (UPF0157) YP_004256584.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005932:IPR015590; KEGG: dra:DR_0813 1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; PRIAM: 1-pyrroline-5-carboxylate dehydrogenase; SPTR: 1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 2; IMG reference gene:2504123233; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative YP_004256585.1 InterPro IPR010259:IPR000209:IPR003137; KEGG: dra:DR_0812 serine protease; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Proteinase inhibitor I9, subtilisin propeptide; Protease-associated domain, PA; SPTR: Serine protease, subtilase family; IMG reference gene:2504123234; PFAM: PA domain; Peptidase inhibitor I9; Subtilase family YP_004256586.1 InterPro IPR000182; KEGG: bha:BH3804 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: BH3804 protein; IMG reference gene:2504123235; PFAM: Acetyltransferase (GNAT) family YP_004256587.1 KEGG: ddr:Deide_20171 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123236 YP_004256588.1 COGs: COG0319 metal-dependent hydrolase; HAMAP: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; InterPro IPR002036; KEGG: ddr:Deide_10740 putative metal-dependent hydrolase (metalloprotease); PFAM: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; SPTR: Putative metalloprotease Deide_10740; TIGRFAM: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; IMG reference gene:2504123237; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family YP_004256589.1 COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: dra:DR_2093 diacylglycerol kinase; PFAM: Diacylglycerol kinase, prokaryotic; SPTR: Diacylglycerol kinase; IMG reference gene:2504123238; PFAM: Prokaryotic diacylglycerol kinase YP_004256590.1 KEGG: cai:Caci_3829 WD-40 repeat protein; SPTR: WD-40 repeat protein; IMG reference gene:2504123239 YP_004256591.1 KEGG: chl:Chy400_0721 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123240 YP_004256592.1 COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476; KEGG: ddr:Deide_03900 putative pyruvate dehydrogenase E1 component subunit beta; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Putative Pyruvate dehydrogenase E1 component subunit beta; IMG reference gene:2504123241; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_004256593.1 COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017596:IPR001017; KEGG: ddr:Deide_03910 putative pyruvate dehydrogenase E1 component subunit alpha; PFAM: Dehydrogenase, E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: 2-oxoisovalerate dehydrogenase, OdbA; TIGRFAM: Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x; IMG reference gene:2504123242; PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit YP_004256594.1 InterPro IPR006124; KEGG: dge:Dgeo_2265 metalloenzyme; PFAM: Metalloenzyme; SPTR: Metalloenzyme, phosphoglyceromutase related; IMG reference gene:2504123243; PFAM: Metalloenzyme superfamily YP_004256595.1 KEGG: rbi:RB2501_12924 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123244; PFAM: NADPH-dependent FMN reductase YP_004256596.1 COGs: COG0171 NAD synthase; HAMAP: NH(3)-dependent NAD(+) synthetase; InterPro IPR003694:IPR022310:IPR022926; KEGG: ddr:Deide_15170 NAD synthetase; PFAM: NAD/GMP synthase; SPTR: NH(3)-dependent NAD(+) synthetase; TIGRFAM: NAD synthase; IMG reference gene:2504123245; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase YP_004256597.1 COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: ddr:Deide_15700 putative sodium/hydrogen exchanger (Na+/H+ antiporter); PFAM: Cation/H+ exchanger; SPTR: Putative Sodium/hydrogen exchanger (Na+/H+ antiporter); IMG reference gene:2504123246; PFAM: Sodium/hydrogen exchanger family YP_004256598.1 COGs: COG1649 conserved hypothetical protein; InterPro IPR003790; KEGG: dra:DR_2412 hypothetical protein; PFAM: Protein of unknown function DUF187; SPTR: Putative uncharacterized protein; IMG reference gene:2504123247; PFAM: Uncharacterised BCR, COG1649 YP_004256599.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: dge:Dgeo_0196 flavin reductase-like protein, FMN-binding; PFAM: Flavin reductase-like, FMN-binding; SMART: Flavin reductase-like, FMN-binding; SPTR: Flavin reductase-like protein, FMN-binding; IMG reference gene:2504123248; PFAM: Flavin reductase like domain YP_004256600.1 InterPro IPR004843; KEGG: dra:DR_2233 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123249; PFAM: Calcineurin-like phosphoesterase YP_004256601.1 KEGG: dra:DR_2232 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123250 YP_004256602.1 COGs: COG4843 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0316; InterPro IPR022930:IPR019264; KEGG: cth:Cthe_2213 hypothetical protein; PFAM: Domain of unknown function DUF2179; SPTR: UPF0316 protein Cther_1128; IMG reference gene:2504123251; PFAM: Uncharacterized protein conserved in bacteria (DUF2179) YP_004256603.1 KEGG: dge:Dgeo_0275 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123252 YP_004256604.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR002933:IPR011650; KEGG: dra:DR_2239 acetylornithine deacetylase, putative; PFAM: Peptidase M20; Peptidase M20, dimerisation; SPTR: Acetylornithine deacetylase, putative; IMG reference gene:2504123253; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain YP_004256605.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: dge:Dgeo_1894 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein Dgeo_1894; TIGRFAM: Uncharacterised protein family UPF0102; IMG reference gene:2504123254; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein YP_004256606.1 COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR001159; KEGG: ddr:Deide_03100 hypothetical protein; PFAM: Double-stranded RNA-binding; SMART: Double-stranded RNA-binding; SPTR: Putative uncharacterized protein; IMG reference gene:2504123255; PFAM: Double-stranded RNA binding motif YP_004256607.1 COGs: COG3698 periplasmic protein; InterPro IPR018711; KEGG: ddr:Deide_04610 putative periplasmic protein; PFAM: Phosphodiester alpha-GlcNAcase; SPTR: Putative periplasmic protein; IMG reference gene:2504123256; PFAM: Predicted periplasmic protein (DUF2233) YP_004256608.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006096:IPR006097; KEGG: dge:Dgeo_0203 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; PRIAM: Leucine dehydrogenase; SMART: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SPTR: Glu/Leu/Phe/Val dehydrogenase; IMG reference gene:2504123258; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004256609.1 KEGG: dge:Dgeo_0054 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123259 YP_004256610.1 COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: dge:Dgeo_1876 fructose 1,6-bisphosphatase II; PFAM: Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase; PRIAM: Fructose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase, class II; TIGRFAM: Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase; IMG reference gene:2504123260; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II YP_004256611.1 IMG reference gene:2504123261 YP_004256612.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: dge:Dgeo_2034 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504123262; PFAM: short chain dehydrogenase YP_004256613.1 COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; HAMAP: Ribonucleotide reductase regulator NrdR-like; InterPro IPR003796:IPR005144; KEGG: dra:DR_0087 transcriptional regulator NrdR; PFAM: ATP-cone; SPTR: Transcriptional repressor NrdR; TIGRFAM: Ribonucleotide reductase regulator NrdR-like; IMG reference gene:2504123263; PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR YP_004256614.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: dra:DR_2514 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123264; PFAM: Acyltransferase YP_004256615.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020842:IPR002198; KEGG: cyj:Cyan7822_6101 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504123265; PFAM: short chain dehydrogenase YP_004256616.1 KEGG: ddr:Deide_02170 putative ferredoxin; SPTR: Putative Ferredoxin; IMG reference gene:2504123266; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit YP_004256617.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: dge:Dgeo_0023 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type Fe3+-siderophores transport system, ATPase component; IMG reference gene:2504123267; PFAM: ABC transporter YP_004256618.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: ddr:Deide_02150 putative Fe3+-siderophore ABC transporter, permease component; PFAM: ABC transporter permease protein; SPTR: Putative Fe3+-siderophore ABC transporter, permease component; IMG reference gene:2504123268; PFAM: FecCD transport family YP_004256619.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: dra:DR_2587 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123269; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004256620.1 InterPro IPR003761; KEGG: dra:DR_2586 hypothetical protein; PFAM: Exonuclease VII, small subunit; SPTR: Putative uncharacterized protein; IMG reference gene:2504123270; PFAM: Exonuclease VII small subunit YP_004256621.1 KEGG: dge:Dgeo_1478 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123271 YP_004256622.1 COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: vpa:VP0503 sodium/alanine symporter; PFAM: Sodium:alanine symporter; SPTR: Sodium/alanine symporter; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2504123272; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_004256623.1 COGs: COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); InterPro IPR005875:IPR003135; KEGG: dge:Dgeo_0081 phosphoribosylaminoimidazole carboxylase, ATPase subunit; PFAM: ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type; PRIAM: Phosphoribosylaminoimidazole carboxylase; SPTR: Phosphoribosylaminoimidazole carboxylase, ATPase subunit; TIGRFAM: Phosphoribosylaminoimidazole carboxylase, ATPase subunit; IMG reference gene:2504123273; PFAM: ATP-grasp domain; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurK protein YP_004256624.1 COGs: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: dra:DR_0023 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: Phosphoribosylaminoimidazole carboxylase, core; PRIAM: Phosphoribosylaminoimidazole carboxylase; SPTR: Phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: Phosphoribosylaminoimidazole carboxylase, core; IMG reference gene:2504123274; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_004256625.1 KEGG: dra:DR_1671 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123275 YP_004256626.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650; KEGG: dra:DR_2493 carboxypeptidase G2; PFAM: Peptidase M20; Peptidase M20, dimerisation; SPTR: Carboxypeptidase G2; IMG reference gene:2504123276; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain YP_004256627.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR013221:IPR004101; KEGG: dge:Dgeo_0083 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: Folylpolyglutamate synthetase; TIGRFAM: Folylpolyglutamate synthetase; IMG reference gene:2504123279; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004256628.1 COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR022689:IPR007167:IPR022687:IPR001367; KEGG: dra:DR_2539 iron dependent repressor, putative; PFAM: Iron dependent repressor; Iron dependent repressor, N-terminal; Ferrous iron transporter, FeoA subunit; SMART: Iron dependent repressor, diptheria toxin type; Ferrous iron transporter, FeoA subunit; SPTR: Iron dependent repressor, putative; IMG reference gene:2504123280; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_004256629.1 InterPro IPR004843; KEGG: ddr:Deide_00300 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123281 YP_004256630.1 KEGG: ddr:Deide_00290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123282 YP_004256631.1 COGs: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport; InterPro IPR007474; KEGG: dge:Dgeo_1993 ApaG; PFAM: ApaG domain; SPTR: ApaG-like protein; IMG reference gene:2504123283; PFAM: Protein of unknown function (DUF525) YP_004256632.1 COGs: COG1363 Cellulase M and related protein; InterPro IPR008007; KEGG: dge:Dgeo_1994 peptidase M42; PFAM: Peptidase M42; PRIAM: Cellulase; SPTR: Peptidase M42; IMG reference gene:2504123284; PFAM: M42 glutamyl aminopeptidase YP_004256633.1 COGs: COG2367 Beta-lactamase class A; KEGG: dra:DR_0433 beta-lactamase, putative; SPTR: Beta-lactamase, putative; IMG reference gene:2504123285 YP_004256634.1 KEGG: tcr:511751.220 hypothetical protein; IMG reference gene:2504123286 YP_004256635.1 COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657; KEGG: dra:DR_0397 molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; Molydopterin dinucleotide-binding domain; PRIAM: Nitrate reductase; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2504123287; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain YP_004256636.1 COGs: COG2947 conserved hypothetical protein; InterPro IPR002740; KEGG: dra:DR_0566 hypothetical protein; PFAM: Protein of unknown function DUF55; SPTR: Putative uncharacterized protein; IMG reference gene:2504123288; PFAM: Protein of unknown function DUF55 YP_004256637.1 IMG reference gene:2504123289 YP_004256638.1 COGs: COG0020 Undecaprenyl pyrophosphate synthase; HAMAP:Di-trans-poly-cis-decaprenylcistransferase-li ke; InterPro IPR001441; KEGG: dra:DR_2447 undecaprenyl pyrophosphate synthase; PFAM:Di-trans-poly-cis-decaprenylcistransferase-lik e; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Undecaprenyl pyrophosphate synthase; TIGRFAM:Di-trans-poly-cis-decaprenylcistransferase- like; IMG reference gene:2504123290; PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_004256639.1 COGs: COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); HAMAP: Polyribonucleotide nucleotidyltransferase; InterProIPR012162:IPR004087:IPR022967:IPR001247:IPR 015847:IPR015848:IPR018111:IPR003029; KEGG: dra:DR_2063 polynucleotide phosphorylase/polyadenylase; PFAM: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; K Homology, type 1, subgroup; Ribosomal protein S1, RNA-binding domain; PRIAM: Polyribonucleotide nucleotidyltransferase; SMART: RNA-binding domain, S1; K Homology; SPTR: Polyribonucleotide nucleotidyltransferase; TIGRFAM: Polyribonucleotide nucleotidyltransferase; IMG reference gene:2504123291; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; Polyribonucleotide nucleotidyltransferase, RNA binding domain; TIGRFAM: polyribonucleotide nucleotidyltransferase YP_004256640.1 KEGG: mrd:Mrad2831_5998 MATE efflux family protein; SPTR: MATE efflux family protein; IMG reference gene:2504123292 YP_004256641.1 KEGG: dra:DR_0040 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123293 YP_004256642.1 KEGG: dge:Dgeo_0399 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123294 YP_004256643.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dra:DR_0170 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504123295; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_004256644.1 COGs: COG1539 Dihydroneopterin aldolase; InterPro IPR006157:IPR006156; KEGG: ddr:Deide_03050 putative dihydroneopterin aldolase, (DhnA); PFAM: Dihydroneopterin aldolase; SMART: Dihydroneopterin aldolase; SPTR: Putative dihydroneopterin aldolase, (DHNA); TIGRFAM: Dihydroneopterin aldolase subgroup; Dihydroneopterin aldolase; IMG reference gene:2504123296; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain YP_004256645.1 COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: dge:Dgeo_0396 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504123297; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_004256646.1 COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; manually curated; IMG reference gene:2504123298; PFAM: Domain of unknown function (DUF955) YP_004256647.1 COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dra:DR_0166 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-CoA-binding protein; IMG reference gene:2504123299; PFAM: Acyl CoA binding protein YP_004256648.1 COGs: COG3853 Uncharacterized protein involved in tellurite resistance; InterPro IPR008863; KEGG: dge:Dgeo_0931 toxic anion resistance; PFAM: Toxic anion resistance; SPTR: Toxic anion resistance; IMG reference gene:2504123301; PFAM: Toxic anion resistance protein (TelA) YP_004256649.1 COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; HAMAP: Methionine sulphoxide reductase B; InterPro IPR002579; KEGG: ddr:Deide_04050 methionine sulfoxide reductase B; PFAM: Methionine sulphoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: Methionine sulphoxide reductase B; IMG reference gene:2504123302; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase YP_004256650.1 COGs: COG2761 dithiol-disulfide isomerase involved in polyketide biosynthesis; InterPro IPR001853; KEGG: dge:Dgeo_2073 DsbA oxidoreductase; PFAM: DSBA-like thioredoxin domain; SPTR: DSBA oxidoreductase; IMG reference gene:2504123303; PFAM: DSBA-like thioredoxin domain YP_004256651.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: ddr:Deide_09560 putative 2-nitropropane dioxygenase (2-NPD) (nitroalkane oxidase); putative membrane protein; PFAM: 2-nitropropane dioxygenase, NPD; PRIAM: 2-nitropropane dioxygenase; SPTR: Putative 2-nitropropane dioxygenase (2-NPD) (Nitroalkane oxidase); putative membrane protein; IMG reference gene:2504123304; PFAM: 2-nitropropane dioxygenase YP_004256652.1 COGs: COG3457 amino acid racemase; InterPro IPR001608; KEGG: fba:FIC_01255 amino acid racemase; PFAM: Alanine racemase, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504123305; PFAM: Alanine racemase, N-terminal domain YP_004256653.1 InterPro IPR000182; KEGG: fba:FIC_01254 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504123306; PFAM: Acetyltransferase (GNAT) family YP_004256654.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593:IPR005936:IPR011546:IPR003959:IPR 000642; KEGG: ddr:Deide_23310 putative cell division protease FtsH; PFAM: Peptidase M41; ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cell division protein FtsH; TIGRFAM: Peptidase M41, FtsH; IMG reference gene:2504123307; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004256655.1 COGs: COG0443 Molecular chaperone; HAMAP: Chaperone DnaK; InterPro IPR012725:IPR013126; KEGG: dra:DR_0129 molecular chaperone DnaK; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; TIGRFAM: Chaperone DnaK; IMG reference gene:2504123308; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_004256656.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); HAMAP: GrpE nucleotide exchange factor; InterPro IPR000740; KEGG: dra:DR_0128 GrpE protein; PFAM: GrpE nucleotide exchange factor; SPTR: Protein grpE; IMG reference gene:2504123309; PFAM: GrpE YP_004256657.1 COGs: COG4628 conserved hypothetical protein; InterPro IPR018668; KEGG: dra:DR_0127 hypothetical protein; PFAM: Protein of unknown function DUF2132; SPTR: Putative uncharacterized protein; IMG reference gene:2504123310; PFAM: Uncharacterized conserved protein (DUF2132) YP_004256658.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939; KEGG: dra:DR_0126 DnaJ protein; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; IMG reference gene:2504123311; PFAM: DnaJ domain; DnaJ C terminal region YP_004256659.1 KEGG: dra:DR_0125 acetyltransferase, putative; SPTR: Acetyltransferase, putative; IMG reference gene:2504123312 YP_004256660.1 COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR005886:IPR001509; KEGG: dra:DR_2202 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; IMG reference gene:2504123313; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase YP_004256661.1 COGs: COG2326 conserved hypothetical protein; InterPro IPR022300:IPR022488; KEGG: dge:Dgeo_2247 hypothetical protein; PFAM: Polyphosphate kinase-2-related; SPTR: Predicted deoxynucleoside kinase; TIGRFAM: Polyphosphate:nucleotide phosphotransferase, PPK2; IMG reference gene:2504123314; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:nucleotide phosphotransferase, PPK2 family YP_004256662.1 COGs: COG2339 membrane protein; KEGG: dge:Dgeo_0328 membrane protein-like protein; SPTR: Membrane protein; IMG reference gene:2504123318 YP_004256663.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; HAMAP: Crossover junction endodeoxyribonuclease RuvC; InterPro IPR002176; KEGG: dra:DR_0440 Holliday junction resolvase; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: Crossover junction endodeoxyribonuclease RuvC; IMG reference gene:2504123319; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_004256664.1 COGs: COG0316 conserved hypothetical protein; InterPro IPR016092:IPR000361; KEGG: dge:Dgeo_0323 HesB/YadR/YfhF; PFAM: FeS cluster biogenesis; SPTR: HesB/YadR/YfhF; TIGRFAM: FeS cluster insertion; IMG reference gene:2504123320; PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein YP_004256665.1 KEGG: dge:Dgeo_0322 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123321 YP_004256666.1 COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223:IPR002586; KEGG: ddr:Deide_21100 putative septum site-determining, cell division inhibitor; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Putative septum site-determining, Cell division inhibitor; TIGRFAM: Septum site-determining protein MinD; IMG reference gene:2504123322; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD YP_004256667.1 COGs: COG0851 Septum formation topological specificity factor; HAMAP: Septum formation topological specificity factor MinE; InterPro IPR005527; KEGG: dra:DR_0751 hypothetical protein; PFAM: Septum formation topological specificity factor MinE; SPTR: Cell division topological specificity factor; TIGRFAM: Septum formation topological specificity factor MinE; IMG reference gene:2504123323; PFAM: Septum formation topological specificity factor MinE; TIGRFAM: cell division topological specificity factor MinE YP_004256668.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR023210; KEGG: ddr:Deide_21050 putative aldo/keto reductase family protein; PFAM: NADP-dependent oxidoreductase domain; SPTR: Putative aldo/keto reductase family protein; IMG reference gene:2504123324; PFAM: Aldo/keto reductase family; TIGRFAM: voltage-dependent potassium channel beta subunit, animal YP_004256669.1 InterPro IPR001450; KEGG: dge:Dgeo_0777 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; IMG reference gene:2504123325; PFAM: 4Fe-4S binding domain YP_004256670.1 KEGG: dra:DR_2329 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123326 YP_004256671.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: ddr:Deide_22150 putative histidine kinase, classic; putative membrane protein; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Putative histidine kinase, classic; putative membrane protein; IMG reference gene:2504123327; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004256672.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dge:Dgeo_2215 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2504123328; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004256673.1 COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: dra:DR_2543 cytidylate kinase; PFAM: Cytidylate kinase domain; PRIAM: Cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504123329; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase YP_004256674.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: dge:Dgeo_0071 peptidase M29, aminopeptidase II; PFAM: Peptidase M29, aminopeptidase II; SPTR: Peptidase M29, aminopeptidase II; IMG reference gene:2504123330; PFAM: Thermophilic metalloprotease (M29) YP_004256675.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: dra:DR_1598 protease, putative; PFAM: Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Protease, putative; IMG reference gene:2504123331; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_004256676.1 COGs: COG3231 Aminoglycoside phosphotransferase; InterPro IPR002575; KEGG: dge:Dgeo_2256 aminoglycoside phosphotransferase; PFAM: Aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase; IMG reference gene:2504123332; PFAM: Phosphotransferase enzyme family YP_004256677.1 COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR003265; KEGG: dra:DR_2584 DNA-3-methyladenine glycosidase II, putative; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: DNA-3-methyladenine glycosidase II, putative; IMG reference gene:2504123333; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004256678.1 KEGG: nvi:100123332 hypothetical protein LOC100123332; SPTR: Putative uncharacterized protein; IMG reference gene:2504123334 YP_004256679.1 KEGG: dge:Dgeo_0108 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123335 YP_004256680.1 KEGG: dge:Dgeo_2257 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123336 YP_004256681.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR022431:IPR020050:IPR007197; KEGG: dra:DR_0064 hypothetical protein; PFAM: Radical SAM; SPTR: Putative uncharacterized protein; TIGRFAM: Menaquinone biosynthesis, SCO4550; FO synthase, subunit 2; IMG reference gene:2504123337; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family YP_004256682.1 IMG reference gene:2504123338 YP_004256683.1 KEGG: dge:Dgeo_2000 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123339; PFAM: Cupin domain YP_004256684.1 COGs: COG3173 aminoglycoside phosphotransferase; InterPro IPR002575; KEGG: dra:DR_A0194 hypothetical protein; PFAM: Aminoglycoside phosphotransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123340; PFAM: Phosphotransferase enzyme family YP_004256685.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: dge:Dgeo_2399 acyl-CoA dehydrogenase-like; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA dehydrogenase, N-terminal; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase-like protein; IMG reference gene:2504123341; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004256686.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020842:IPR002198; KEGG: gmc:GY4MC1_2868 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504123342; PFAM: short chain dehydrogenase YP_004256687.1 InterPro IPR001647; KEGG: ava:Ava_1093 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504123343; PFAM: Bacterial regulatory proteins, tetR family YP_004256688.1 COGs: COG0550 Topoisomerase IA; InterProIPR006171:IPR003601:IPR003602:IPR005733:IPR 013497; KEGG: dge:Dgeo_2001 DNA topoisomerase I; PFAM: DNA topoisomerase, type IA, central; Toprim domain; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial-type; IMG reference gene:2504123344; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_004256689.1 InterPro IPR003848; KEGG: dge:Dgeo_2002 hypothetical protein; PFAM: Domain of unknown function DUF218; SPTR: Putative uncharacterized protein; IMG reference gene:2504123345; PFAM: DUF218 domain YP_004256690.1 COGs: COG0728 membrane protein putative virulence factor; InterPro IPR004268; KEGG: dge:Dgeo_2003 integral membrane protein MviN; PFAM: Flagellin assembly, membrane protein MviN; SPTR: Integral membrane protein MviN; TIGRFAM: Flagellin assembly, membrane protein MviN; IMG reference gene:2504123346; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN YP_004256691.1 COGs: COG1427 periplasmic solute-binding protein; InterPro IPR003773; KEGG: dra:DR_0370 hypothetical protein; PFAM: Protein of unknown function DUF178; SPTR: Putative uncharacterized protein; IMG reference gene:2504123348; PFAM: Putative periplasminc binding protein (DUF178) YP_004256692.1 KEGG: msv:Mesil_1489 protein of unknown function DUF422; SPTR: Putative uncharacterized protein; IMG reference gene:2504123349 YP_004256693.1 IMG reference gene:2504123350 YP_004256694.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR022432:IPR020050:IPR007197; KEGG: dra:DR_0366 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: Menaquinone biosynthesis, SCO4494, predicted; FO synthase, subunit 2; IMG reference gene:2504123351; PFAM: Radical SAM superfamily; TIGRFAM: putative menaquinone biosynthesis protein, SCO4494 family; radical SAM domain protein, CofH subfamily YP_004256695.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dge:Dgeo_0530 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504123352; PFAM: Major Facilitator Superfamily; TIGRFAM: Multidrug resistance protein YP_004256696.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dge:Dgeo_0528 NADH dehydrogenase; PFAM: Nitroreductase-like; PRIAM: NADH dehydrogenase; SPTR: NADH dehydrogenase; IMG reference gene:2504123353; PFAM: Nitroreductase family YP_004256697.1 COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: dra:DR_1969 hypothetical protein; PFAM: Helix-turn-helix, HxlR type; SPTR: Putative uncharacterized protein; IMG reference gene:2504123354; PFAM: HxlR-like helix-turn-helix YP_004256698.1 InterPro IPR013096; KEGG: ddr:Deide_04920 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative uncharacterized protein; IMG reference gene:2504123355; PFAM: Cupin domain YP_004256699.1 KEGG: scl:sce7068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123356 YP_004256700.1 COGs: COG2124 Cytochrome P450; InterPro IPR001128; KEGG: hau:Haur_3072 cytochrome P450; PFAM: Cytochrome P450; SPTR: Cytochrome P450; IMG reference gene:2504123357; PFAM: Cytochrome P450 YP_004256701.1 KEGG: ret:RHE_PE00189 hypothetical protein; SPTR: Hypothetical conserved protein; IMG reference gene:2504123358; PFAM: NACHT domain YP_004256702.1 COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; HAMAP: Glycine cleavage system P protein, homodimeric; InterPro IPR003437:IPR020580; KEGG: dra:DR_1809 glycine dehydrogenase; PFAM: Glycine cleavage system P-protein, N-terminal; SPTR: Glycine dehydrogenase [decarboxylating]; TIGRFAM: Glycine cleavage system P protein, homodimeric; IMG reference gene:2504123359; PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating) YP_004256703.1 COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); HAMAP: Glycine cleavage H-protein; InterPro IPR002930:IPR017453; KEGG: ddr:Deide_04950 glycine cleavage system protein H; PFAM: Glycine cleavage H-protein; SPTR: Glycine cleavage system H protein; TIGRFAM: Glycine cleavage H-protein, subgroup; IMG reference gene:2504123360; PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein YP_004256704.1 COGs: COG0404 Glycine cleavage system T protein (aminomethyltransferase); HAMAP: Aminomethyltransferase; InterPro IPR022903:IPR006223:IPR006222:IPR013977; KEGG: ddr:Deide_04960 putative aminomethyltransferase (glycine cleavage system T protein); PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel; PRIAM: Aminomethyltransferase; SPTR: Aminomethyltransferase; TIGRFAM: Glycine cleavage system T protein; IMG reference gene:2504123361; PFAM: Aminomethyltransferase folate-binding domain; Glycine cleavage T-protein C-terminal barrel domain; TIGRFAM: glycine cleavage system T protein YP_004256705.1 COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR006286:IPR002818; KEGG: dra:DR_1199 protease I; PFAM: ThiJ/PfpI; SPTR: Protease I; TIGRFAM: Peptidase C56, PfpI; IMG reference gene:2504123362; PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family YP_004256706.1 COGs: COG0358 DNA primase; InterPro IPR002694:IPR006171:IPR006295:IPR013264; KEGG: dge:Dgeo_1910 DNA primase; PFAM: DNA primase, catalytic core, N-terminal; Zinc finger, CHC2-type; Toprim domain; SPTR: DNA primase; TIGRFAM: DNA primase, DnaG; IMG reference gene:2504123363; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core YP_004256707.1 COGs: COG0796 Glutamate racemase; HAMAP: Glutamate racemase; InterPro IPR004391:IPR015942; KEGG: dge:Dgeo_2085 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Glutamate racemase; SPTR: Glutamate racemase; TIGRFAM: Glutamate racemase; IMG reference gene:2504123364; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_004256708.1 InterPro IPR013217; KEGG: dra:DR_1676 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Putative uncharacterized protein; IMG reference gene:2504123365; PFAM: Methyltransferase domain YP_004256709.1 COGs: COG4374 conserved hypothetical protein; InterPro IPR002716; KEGG: nar:Saro_3972 PilT domain-containing protein; PFAM: PilT protein, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504123366; PFAM: PIN domain YP_004256710.1 COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; HAMAP: tRNA (guanine-N-7) methyltransferase; InterPro IPR003358; KEGG: dra:DR_1680 hypothetical protein; PFAM: tRNA (guanine-N-7) methyltransferase; SPTR: tRNA (guanine-N(7)-)-methyltransferase; IMG reference gene:2504123367; PFAM: Putative methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase YP_004256711.1 COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; InterPro IPR002218; KEGG: dge:Dgeo_2091 glucose-inhibited division protein A; PFAM: Glucose-inhibited division protein A-related; SPTR: Flavin-dependent tRNA uridine 5-carboxymethylaminomethyl modification enzyme, GidA; IMG reference gene:2504123368; PFAM: Glucose inhibited division protein A YP_004256712.1 KEGG: ddr:Deide_00440 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123369; PFAM: Predicted membrane protein (DUF2231) YP_004256713.1 KEGG: sul:SYO3AOP1_0742 phosphate ABC transporter, inner membrane subunit PstC; SPTR: Phosphate ABC transporter, permease protein PstC; IMG reference gene:2504123370 YP_004256714.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: dge:Dgeo_2345 DNA processing protein DprA, putative; PFAM: DNA recombination-mediator protein A; SPTR: DNA processing protein DprA, putative; TIGRFAM: DNA recombination-mediator protein A; IMG reference gene:2504123371; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_004256715.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR003660; KEGG: ddr:Deide_23500 putative histidine kinase, classic; putative membrane protein; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; SPTR: Putative histidine kinase, classic; putative membrane protein; IMG reference gene:2504123372; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004256716.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dra:DR_2415 DNA-binding response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: DNA-binding response regulator; IMG reference gene:2504123373; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004256717.1 KEGG: ddr:Deide_23480 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504123374 YP_004256718.1 COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: ddr:Deide_23470 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; PRIAM: Dihydrolipoyllysine-residue acetyltransferase; SPTR: Putative dihydrolipoyllysine-residue succinyltransferase (Succinyl-CoA:dihydrolipoamide S-succinyltransferase); IMG reference gene:2504123375; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form YP_004256719.1 COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476; KEGG: dge:Dgeo_2339 transketolase, central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 2-oxoisovalerate dehydrogenase, ODBB; IMG reference gene:2504123376; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_004256720.1 COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: dge:Dgeo_2338 pyruvate dehydrogenase (lipoamide); PFAM: Dehydrogenase, E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: 2-oxoisovalerate dehydrogenase, OdbA; IMG reference gene:2504123377; PFAM: Dehydrogenase E1 component YP_004256721.1 COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; InterPro IPR004416:IPR002218; KEGG: ddr:Deide_23420 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: Glucose-inhibited division protein A-related; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; TIGRFAM: Glucose-inhibited division protein A; IMG reference gene:2504123378; PFAM: Glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A YP_004256722.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; HAMAP: rRNA small subunit methyltransferase G; InterPro IPR003682; KEGG: dge:Dgeo_2335 16S rRNA methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: rRNA small subunit methyltransferase G; IMG reference gene:2504123379; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA (guanine(527)-N(7))-methyltransferase GidB YP_004256723.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: dge:Dgeo_2334 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: ATPase involved in plasmide/chromosome partitioning, ParA/Soj-like protein; IMG reference gene:2504123380; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004256724.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: dra:DR_0012 chromosome partitioning protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: Probable chromosome 1-partitioning protein parB; TIGRFAM: ParB-like partition protein; IMG reference gene:2504123381; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004256725.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: ddr:Deide_22300 putative universal stress protein; PFAM: UspA; SPTR: Putative universal stress protein; IMG reference gene:2504123382; PFAM: Universal stress protein family YP_004256726.1 COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR011304:IPR001236:IPR022383; KEGG: ddr:Deide_22290 putative L-lactate dehydrogenase, precursor (L-lactic acid dehydrogenase); PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; PRIAM: L-lactate dehydrogenase; SPTR: Putative L-lactate dehydrogenase, (L-lactic acid dehydrogenase); TIGRFAM: L-lactate dehydrogenase; IMG reference gene:2504123383; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: L-lactate dehydrogenase YP_004256727.1 KEGG: dge:Dgeo_0154 OstA-like protein protein; SPTR: OstA-like protein protein; IMG reference gene:2504123384; PFAM: OstA-like protein YP_004256728.1 InterPro IPR005653; KEGG: dge:Dgeo_0153 OstA-like protein protein; PFAM: Organic solvent tolerance-like, N-terminal; SPTR: OstA-like protein protein; IMG reference gene:2504123385; PFAM: OstA-like protein; TIGRFAM: lipopolysaccharide transport periplasmic protein LptA YP_004256729.1 KEGG: dge:Dgeo_0152 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123386 YP_004256730.1 KEGG: dra:DR_1920 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123387 YP_004256731.1 COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: dra:DR_A0138 amino acid ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Amino acid ABC transporter, permease protein; IMG reference gene:2504123388; PFAM: Binding-protein-dependent transport system inner membrane component YP_004256732.1 COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: dra:DR_A0137 amino acid ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid ABC transporter, ATP-binding protein; IMG reference gene:2504123389; PFAM: ABC transporter YP_004256733.1 COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: dra:DR_A0136 amino acid ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Amino acid ABC transporter, permease protein; IMG reference gene:2504123390; PFAM: Binding-protein-dependent transport system inner membrane component YP_004256734.1 COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: dra:DR_A0135 ABC transporter, periplasmic substrate-binding protein, putative; PFAM: ABC-type glycine betaine transport system, substrate-binding domain; SPTR: ABC transporter, periplasmic substrate-binding protein, putative; IMG reference gene:2504123391; PFAM: Substrate binding domain of ABC-type glycine betaine transport system YP_004256735.1 InterPro IPR010093:IPR010260; KEGG: msv:Mesil_0057 DNA binding domain protein, excisionase family; PFAM: Prophage CP4-57 regulatory; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: Excisionase/Xis, DNA-binding; IMG reference gene:2504123392; TIGRFAM: DNA binding domain, excisionase family YP_004256736.1 KEGG: cre:CHLREDRAFT_170673 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2504123393 YP_004256737.1 COGs: COG2957 Peptidylarginine deiminase; InterPro IPR007466; KEGG: dra:DR_2359 hypothetical protein; PFAM: Peptidyl-arginine deiminase, Porphyromonas-type; PRIAM: Agmatine deiminase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123394; PFAM: Porphyromonas-type peptidyl-arginine deiminase YP_004256738.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523; KEGG: dge:Dgeo_0150 Mg2+ transporter protein, CorA-like protein; PFAM: Mg2+ transporter protein, CorA-like; SPTR: Mg2+ transporter protein, CorA-like protein; IMG reference gene:2504123395; PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA) YP_004256739.1 COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708; KEGG: ddr:Deide_03880 putative 60 kDa inner membrane insertion protein, membrane protein OxaA; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative 60 kDa inner membrane insertion protein, Membrane protein OxaA; TIGRFAM: Membrane insertion protein, OxaA/YidC; IMG reference gene:2504123396; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain YP_004256740.1 COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: ddr:Deide_01330 50S ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32; TIGRFAM: Ribosomal protein L32p; IMG reference gene:2504123397; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32 YP_004256741.1 InterPro IPR001845; KEGG: tcu:Tcur_2204 hypothetical protein; SMART: HTH transcriptional regulator, ArsR; SPTR: Putative uncharacterized protein; IMG reference gene:2504123398 YP_004256742.1 COGs: COG2367 Beta-lactamase class A; KEGG: hau:Haur_3839 beta-lactamase class A-like; SPTR: Beta-lactamase class A-like; IMG reference gene:2504123399 YP_004256743.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; HAMAP: UbiE/COQ5 methyltransferase; InterPro IPR004033; KEGG: dra:DR_2405 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; SPTR: Menaquinone biosynthesis methyltransferase ubiE; TIGRFAM: UbiE/COQ5 methyltransferase; IMG reference gene:2504123400; PFAM: ubiE/COQ5 methyltransferase family; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases YP_004256744.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR010962:IPR004839; KEGG: ddr:Deide_22740 putative glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase); PFAM: Aminotransferase, class I/classII; PRIAM: Glycine C-acetyltransferase; SPTR: Putative glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase); TIGRFAM: Pyridoxal phosphate-dependent acyltransferase, putative; IMG reference gene:2504123401; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative YP_004256745.1 InterPro IPR000551; KEGG: ddr:Deide_08155 hypothetical protein; PFAM: HTH transcriptional regulator, MerR; SPTR: Putative uncharacterized protein; IMG reference gene:2504123402; TIGRFAM: DNA binding domain, excisionase family YP_004256746.1 InterPro IPR000073; KEGG: dra:DR_1403 hydrolase-related protein; PFAM: Alpha/beta hydrolase fold-1; SPTR: Hydrolase-related protein; IMG reference gene:2504123403; PFAM: alpha/beta hydrolase fold YP_004256747.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: dra:DR_1030 aminotransferase, putative; PFAM: Aminotransferase, class I/classII; PRIAM: Aromatic-amino-acid transaminase; SPTR: Aminotransferase, putative; IMG reference gene:2504123404; PFAM: Aminotransferase class I and II YP_004256748.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: mrb:Mrub_1048 ABC transporter-like protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Ectoine/hydroxyectoine ABC transporter, ATP-binding protein; IMG reference gene:2504123405; PFAM: ABC transporter YP_004256749.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: dra:DR_1028 amino acid ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Amino acid ABC transporter, permease protein; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM domain, His/Glu/Gln/Arg/opine family; IMG reference gene:2504123406; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_004256750.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001320:IPR001638; KEGG: mrb:Mrub_1044 extracellular solute-binding protein family 3; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; Ionotropic glutamate receptor; SPTR: Extracellular solute-binding protein family 3; IMG reference gene:2504123407; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004256751.1 COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR010627:IPR000045; KEGG: dge:Dgeo_0374 peptidase A24A-like protein; PFAM: Peptidase A24A, N-terminal; Peptidase A24A, prepilin type IV; PRIAM: Prepilin peptidase; SPTR: Peptidase A24A-like protein; IMG reference gene:2504123408; PFAM: Bacterial Peptidase A24 N-terminal domain; Type IV leader peptidase family YP_004256752.1 KEGG: ddr:Deide_19890 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504123409 YP_004256753.1 InterPro IPR000182; KEGG: ddr:Deide_19910 putative N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative N-acetyltransferase; IMG reference gene:2504123410; PFAM: Acetyltransferase (GNAT) family YP_004256754.1 KEGG: ddr:Deide_19920 putative GCN5-related N-acetyltransferase; SPTR: Putative GCN5-related N-acetyltransferase; IMG reference gene:2504123411 YP_004256755.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; HAMAP: C4-dicarboxylate transport protein; InterPro IPR001991; KEGG: dra:DR_2525 C4-dicarboxylate transport protein; PFAM: Sodium:dicarboxylate symporter; SPTR: C4-dicarboxylate transport protein; IMG reference gene:2504123412; PFAM: Sodium:dicarboxylate symporter family YP_004256756.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: dra:DR_0081 hypothetical protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: Putative uncharacterized protein; IMG reference gene:2504123413; PFAM: GlcNAc-PI de-N-acetylase YP_004256757.1 KEGG: cfa:490395 degenerative spermatocyte homolog 1, lipid desaturase (Drosophila); SPTR: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; IMG reference gene:2504123414 YP_004256758.1 KEGG: ddr:Deide_03030 putative DNA repair regulator protein IrrE (PprI); SPTR: Putative DNA repair regulator protein IrrE (PprI); IMG reference gene:2504123415; PFAM: Domain of unknown function (DUF955) YP_004256759.1 KEGG: cmi:CMM_1574 putative membrane bound esterase; SPTR: Putative membrane protein; IMG reference gene:2504123416 YP_004256760.1 COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR006159:IPR006099:IPR006158; KEGG: dge:Dgeo_1320 methylmalonyl-CoA mutase; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; Cobalamin (vitamin B12)-binding; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, beta subunit; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; Methylmalonyl-CoA mutase, C-terminal; IMG reference gene:2504123417; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain YP_004256761.1 COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: dra:DR_0183 glutamate synthase, large subunit; PFAM: Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, central-C; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase, large subunit; IMG reference gene:2504123418; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II YP_004256762.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR006005:IPR013027; KEGG: dra:DR_0182 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase, small subunit; TIGRFAM: Glutamate synthase, NADH/NADPH, small subunit 1; IMG reference gene:2504123419; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit YP_004256763.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: ddr:Deide_08110 putative ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Putative ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504123420; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase YP_004256764.1 COGs: COG2045 Phosphosulfolactate phosphohydrolase; InterPro IPR005238; KEGG: dge:Dgeo_1318 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; SPTR: Probable 2-phosphosulfolactate phosphatase; IMG reference gene:2504123421; PFAM: 2-phosphosulpholactate phosphatase YP_004256765.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR005730:IPR022643; KEGG: dra:DR_1410 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, C-terminal; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: Carboxynorspermidine decarboxylase; IMG reference gene:2504123422; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase YP_004256766.1 COGs: COG3695 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ddr:Deide_22770 putative methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase); IMG reference gene:2504123423; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain YP_004256767.1 InterPro IPR003088; KEGG: ddr:Deide_22760 putative cytochrome c; PFAM: Cytochrome c, class I; SPTR: Putative Cytochrome c; IMG reference gene:2504123424; PFAM: Cytochrome c YP_004256768.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: dra:DR_1589 fructose-bisphosphate aldolase; PFAM: Ketose-bisphosphate aldolase, class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class 2; Ketose-bisphosphate aldolase, class-II; IMG reference gene:2504123425; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist YP_004256769.1 InterPro IPR004843; KEGG: dge:Dgeo_0217 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; IMG reference gene:2504123426; PFAM: Calcineurin-like phosphoesterase YP_004256770.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: dge:Dgeo_0219 twin-arginine translocation pathway signal; PFAM: Metallo-dependent phosphatase; SPTR: Calcineurin like phosphoesterase; IMG reference gene:2504123427; PFAM: Calcineurin-like phosphoesterase YP_004256771.1 COGs: COG0297 Glycogen synthase; HAMAP: Glycogen/starch synthases, ADP-glucose type; InterPro IPR011835:IPR013534:IPR001296; KEGG: dra:DR_0594 glycogen synthase; PFAM: Starch synthase, catalytic domain; Glycosyl transferase, group 1; PRIAM: Starch synthase; SPTR: Glycogen synthase; TIGRFAM: Glycogen/starch synthases, ADP-glucose type; IMG reference gene:2504123428; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type YP_004256772.1 COGs: COG1002 Type II restriction enzyme methylase subunits; KEGG: plm:Plim_2985 hypothetical protein; SPTR: Type II restriction endonuclease; IMG reference gene:2504120855 YP_004256773.1 KEGG: bfa:Bfae_02950 signal transduction histidine kinase; IMG reference gene:2504120856 YP_004256774.1 KEGG: sma:SAV_2804 pep2 protein; SPTR: Putative 3-hydroxyisobutyrate dehydrogenase; IMG reference gene:2504120857 YP_004256775.1 KEGG: bfo:BRAFLDRAFT_77852 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120858 YP_004256776.1 KEGG: coc:Coch_1917 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120859 YP_004256777.1 COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR001604:IPR008613:IPR020821; KEGG: ddr:Deide_1p00121 putative DNA/RNA endonuclease G; PFAM: DNA/RNA non-specific endonuclease; Excalibur calcium-binding domain; SMART: DNA/RNA non-specific endonuclease; Extracellular Endonuclease, subunit A; Excalibur calcium-binding domain; SPTR: Putative DNA/RNA endonuclease G; IMG reference gene:2504120860; PFAM: Excalibur calcium-binding domain; DNA/RNA non-specific endonuclease YP_004256778.1 KEGG: rca:Rcas_3547 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120861 YP_004256779.1 KEGG: pae:PA2402 peptide synthase; SPTR: Toxin secretion ABC transporter ATP-binding protein; IMG reference gene:2504120862 YP_004256780.1 KEGG: msm:MSMEG_0301 oxidoreductase, FAD-binding; SPTR: Oxidoreductase, FAD-binding; IMG reference gene:2504120864 YP_004256781.1 IMG reference gene:2504120865 YP_004256782.1 KEGG: dae:Dtox_2882 protein of unknown function DUF456; SPTR: ATP synthase subunit a; IMG reference gene:2504120866 YP_004256783.1 KEGG: nvi:100121729 similar to GA19649-PA; SPTR: Disks large-like protein 5; IMG reference gene:2504120867 YP_004256784.1 KEGG: alv:Alvin_2892 endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; IMG reference gene:2504120868 YP_004256785.1 KEGG: tfu:Tfu_0056 WD-40 repeat-containing tyrosine protein kinase; SPTR: Tyrosine protein kinase:WD-40 repeat:Serine/threonine protein kinase; IMG reference gene:2504120869 YP_004256786.1 KEGG: ure:UREG_06918 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120870 YP_004256787.1 KEGG: csa:Csal_2031 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120871 YP_004256788.1 KEGG: ppp:PHYPADRAFT_165428 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2504120872 YP_004256789.1 KEGG: bpd:BURPS668_2463 uracil-DNA glycosylase; SPTR: Uracil-DNA glycosylase, family 4; IMG reference gene:2504120873 YP_004256790.1 KEGG: bur:Bcep18194_B0701 TPR repeat-containing protein; SPTR: Nucleoprotein TPR; IMG reference gene:2504120874 YP_004256791.1 KEGG: mpo:Mpop_4801 ATP-dependent helicase HrpB; SPTR: ATP-dependent helicase HrpB; IMG reference gene:2504120875 YP_004256792.1 KEGG: lif:LinJ28.1630 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120876 YP_004256793.1 KEGG: mdo:100031044 hypothetical protein LOC100031044; SPTR: Putative uncharacterized protein; IMG reference gene:2504120877 YP_004256794.1 IMG reference gene:2504120878 YP_004256795.1 KEGG: msv:Mesil_3532 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120879; PFAM: Putative CRISPR-associated protein (Cas_VVA1548); TIGRFAM: putative CRISPR-associated protein, VVA1548 family YP_004256796.1 KEGG: bay:RBAM_013940 YkuP; SPTR: Sulfate ABC transporter, ATPase subunit; IMG reference gene:2504120880 YP_004256797.1 KEGG: nhl:Nhal_0962 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120881 YP_004256798.1 KEGG: ang:An01g12370 hypothetical protein; IMG reference gene:2504120882 YP_004256799.1 KEGG: ara:Arad_1187 acyl-CoA dehydrogenase protein; SPTR: Acyl-CoA dehydrogenase protein; IMG reference gene:2504120883 YP_004256800.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: dge:Dgeo_0165 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504120884; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004256801.1 KEGG: cyh:Cyan8802_0152 polyprenyl synthetase; SPTR: Polyprenyl synthetase; IMG reference gene:2504120885 YP_004256802.1 IMG reference gene:2504120886 YP_004256803.1 InterPro IPR000424; KEGG: dge:Dgeo_2964 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; IMG reference gene:2504120887; PFAM: Single-strand binding protein family YP_004256804.1 KEGG: fra:Francci3_3067 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120888 YP_004256805.1 KEGG: vpa:VP3013 DNA-dependent helicase II; SPTR: ATP-dependent DNA helicase UvrD/PcrA; IMG reference gene:2504120889 YP_004256806.1 InterPro IPR014914; KEGG: dge:Dgeo_2974 RES domain-containing protein; PFAM: RES; SMART: RES; SPTR: RES domain protein; IMG reference gene:2504120890; PFAM: RES domain YP_004256807.1 IMG reference gene:2504120891 YP_004256808.1 KEGG: mkm:Mkms_2957 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120892 YP_004256809.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: jan:Jann_1886 lytic transglycosylase, catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Transglycosylase SLT domain protein; IMG reference gene:2504120893; PFAM: Transglycosylase SLT domain YP_004256810.1 KEGG: cai:Caci_8822 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120894 YP_004256811.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935:IPR001650:IPR014001; KEGG: msv:Mesil_3640 type III restriction protein res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Type III restriction protein res subunit; IMG reference gene:2504120895; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit YP_004256812.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: dge:Dgeo_0165 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504120896; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004256813.1 KEGG: mno:Mnod_8123 transcriptional regulator, LacI family; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504120897 YP_004256814.1 KEGG: kva:Kvar_1586 nitrogenase cofactor biosynthesis protein NifB; SPTR: Putative uncharacterized protein; IMG reference gene:2504120898 YP_004256815.1 COGs: COG0328 Ribonuclease HI; HAMAP: Ribonuclease H; InterPro IPR002156:IPR022892; KEGG: ret:RHE_CH00963 ribonuclease H; PFAM: Ribonuclease H domain; PRIAM: Ribonuclease H; SPTR: Ribonuclease H; IMG reference gene:2504120899; PFAM: RNase H YP_004256816.1 KEGG: cpw:CPC735_064180 aryl-alcohol dehydrogenase, putative; SPTR: Aryl-alcohol dehydrogenase, putative; IMG reference gene:2504120900 YP_004256817.1 KEGG: mem:Memar_1339 multi-sensor signal transduction histidine kinase; SPTR: Putative uncharacterized protein; IMG reference gene:2504120901 YP_004256818.1 KEGG: cti:RALTA_B2176 hypothetical protein; SPTR: Modular polyketide synthase; IMG reference gene:2504120902 YP_004256819.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: ddr:Deide_00120 putative single-stranded DNA-binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504120903; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004256820.1 KEGG: cbr:CBG17595 C. briggsae CBR-SMA-9 protein; SPTR: C. briggsae CBR-SMA-9 protein; IMG reference gene:2504120904 YP_004256821.1 KEGG: sse:Ssed_0982 hypothetical protein; SPTR: Pantoate--beta-alanine ligase; IMG reference gene:2504120905 YP_004256822.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: dsh:Dshi_1605 lytic murein transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic murein transglycosylase; IMG reference gene:2504120906; PFAM: Transglycosylase SLT domain YP_004256823.1 InterPro IPR018392:IPR002482; KEGG: dge:Dgeo_1490 peptidase C39, bacteriocin processing; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase C39; IMG reference gene:2504120907; PFAM: Peptidase C39 family; LysM domain YP_004256824.1 KEGG: dat:HRM2_44720 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120908 YP_004256825.1 KEGG: avn:Avin_31800 Na+/H+ antiporter NhaP protein; SPTR: Na+/H+ antiporter NhaP protein; IMG reference gene:2504120910 YP_004256826.1 KEGG: ddr:Deide_1p01110 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120911 YP_004256827.1 KEGG: dge:Dgeo_2992 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120912 YP_004256828.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: ddr:Deide_2p00002 putative ParB-like partition protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: Putative ParB-like partition protein; TIGRFAM: ParB-like partition protein; IMG reference gene:2504120913; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004256829.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: oan:Oant_3185 cobyrinic acid ac-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase; IMG reference gene:2504120914; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004256830.1 InterPro IPR003115:IPR004437; KEGG: dge:Dgeo_2993 ParB-like partition protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein; IMG reference gene:2504120915; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004256831.1 KEGG: dge:Dgeo_2994 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120916 YP_004256832.1 InterPro IPR003593; KEGG: dge:Dgeo_2995 ATPase; SMART: ATPase, AAA+ type, core; SPTR: ATPase associated with various cellular activities AAA_5; IMG reference gene:2504120917; PFAM: AAA domain (dynein-related subfamily) YP_004256833.1 KEGG: mes:Meso_3721 luciferase-like; SPTR: Surface presentation of antigens; secretory proteins; IMG reference gene:2504120918 YP_004256834.1 InterPro IPR002035; KEGG: dge:Dgeo_2996 Zn-dependent peptidase; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: Zn-dependent peptidase; IMG reference gene:2504120919; PFAM: VWA domain containing CoxE-like protein YP_004256835.1 InterPro IPR003356:IPR001650:IPR014001; KEGG: aau:AAur_pTC20002 putative helicase; PFAM: Helicase, C-terminal; DNA methylase, adenine-specific; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: DEAD-like helicase; IMG reference gene:2504120920; PFAM: N-6 DNA Methylase; Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004256836.1 KEGG: pkn:PKH_090100 CCR4-Not complex subunit; SPTR: CCR4-Not complex subunit, putative; IMG reference gene:2504120921 YP_004256837.1 KEGG: dge:Dgeo_0295 hypothetical protein; SPTR: Single-stranded DNA-binding protein DdrB; IMG reference gene:2504120922 YP_004256838.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006345; KEGG: ddr:Deide_16210 putative exodeoxyribonuclease V, alpha subunit; PRIAM: Exodeoxyribonuclease V; SPTR: Putative exodeoxyribonuclease V, alpha subunit; TIGRFAM: DNA helicase, RecD/TraA type; IMG reference gene:2504120923; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, putative, RecD/TraA family YP_004256839.1 KEGG: dth:DICTH_1412 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120924 YP_004256840.1 COGs: COG0550 Topoisomerase IA; InterPro IPR006171:IPR013497:IPR005733:IPR003601:IPR003602; KEGG: srt:Srot_2601 DNA topoisomerase I; PFAM: DNA topoisomerase, type IA, central; Toprim domain; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; Toprim domain; DNA topoisomerase, type IA, domain 2; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial-type; IMG reference gene:2504120925; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_004256841.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212:IPR003593; KEGG: cyj:Cyan7822_4571 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SMART: ATPase, AAA+ type, core; SPTR: UvrD/REP helicase; IMG reference gene:2504120926; PFAM: UvrD/REP helicase YP_004256842.1 KEGG: olu:OSTLU_32991 predicted protein; SPTR: Predicted protein; IMG reference gene:2504120927 YP_004256843.1 InterPro IPR022273; KEGG: ddi:DDB_G0295719 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: ParB-related, ThiF-related cassette, protein E; IMG reference gene:2504120928; TIGRFAM: PRTRC system protein E YP_004256844.1 InterPro IPR022289; KEGG: rpf:Rpic12D_5240 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: ParB-related, ThiF-related cassette, protein C; IMG reference gene:2504120929; TIGRFAM: PRTRC system protein C YP_004256845.1 KEGG: vcn:VOLCADRAFT_89258 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120930 YP_004256846.1 KEGG: hma:rrnAC1876 CtaG modification methylase; SPTR: Predicted protein; IMG reference gene:2504120931 YP_004256847.1 KEGG: dar:Daro_2538 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120932; TIGRFAM: PRTRC system protein B YP_004256848.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR022500; KEGG: ppd:Ppro_3825 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: UBA/THIF-type NAD/FAD binding protein; TIGRFAM: ParB-related, ThiF-related cassette, ThiF; IMG reference gene:2504120933; PFAM: ThiF family; TIGRFAM: PRTRC system ThiF family protein YP_004256849.1 KEGG: tgo:TGME49_104650 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120934 YP_004256850.1 InterPro IPR022280; KEGG: bge:BC1002_7244 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: ParB-related, ThiF-related cassette, protein B; IMG reference gene:2504120935; TIGRFAM: PRTRC system protein B YP_004256851.1 InterPro IPR000594:IPR022500; KEGG: ppd:Ppro_3825 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: UBA/THIF-type NAD/FAD binding protein; TIGRFAM: ParB-related, ThiF-related cassette, ThiF; IMG reference gene:2504120936; PFAM: ThiF family; TIGRFAM: PRTRC system ThiF family protein YP_004256852.1 KEGG: rce:RC1_1910 hypothetical protein; SPTR: Protease HtpX homolog 2; IMG reference gene:2504120937 YP_004256853.1 KEGG: aag:AaeL_AAEL010252 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120938 YP_004256854.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dra:DR_A0065 DNA-binding protein HB; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: DNA-binding protein HU; IMG reference gene:2504120939; PFAM: Bacterial DNA-binding protein YP_004256855.1 KEGG: kra:Krad_4621 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120940 YP_004256856.1 KEGG: sjp:SJA_C1-18250 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120941 YP_004256857.1 KEGG: sal:Sala_0241 peptidase M48, Ste24p; SPTR: Peptidase M48, Ste24p; IMG reference gene:2504120942 YP_004256858.1 KEGG: pcs:Pc12g12170 hypothetical protein; IMG reference gene:2504120943 YP_004256859.1 KEGG: vvi:100242355 hypothetical protein LOC100242355; SPTR: Putative uncharacterized protein; IMG reference gene:2504120944 YP_004256860.1 COGs: COG0338 Site-specific DNA methylase; InterPro IPR012327; KEGG: msv:Mesil_3649 D12 class N6 adenine-specific DNA methyltransferase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: D12 class N6 adenine-specific DNA methyltransferase; IMG reference gene:2504120945; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_004256861.1 KEGG: kfl:Kfla_4384 hypothetical protein; SPTR: Signal transduction protein containing GAF and PtsI domains; IMG reference gene:2504120946 YP_004256862.1 KEGG: cre:CHLREDRAFT_6783 SNF2 superfamily protein; SPTR: SNF2 superfamily protein; IMG reference gene:2504120947 YP_004256863.1 KEGG: vvi:100255461 hypothetical protein LOC100255461; SPTR: Whole genome shotgun sequence of line PN40024, scaffold_30.assembly12x; IMG reference gene:2504120948 YP_004256864.1 KEGG: cci:CC1G_06412 hypothetical protein; SPTR: Replication protein A; IMG reference gene:2504120949 YP_004256865.1 KEGG: amr:AM1_3746 hypothetical protein; SPTR: Junctophilin 2; IMG reference gene:2504120950 YP_004256866.1 COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR001959:IPR010095; KEGG: mrb:Mrub_2213 transposase IS605 OrfB family; PFAM: Transposase, probable, IS891/IS1136/IS1341; Transposase, IS605 OrfB, C-terminal; SPTR: Transposase, IS605 OrfB family; TIGRFAM: Transposase, IS605 OrfB, C-terminal; IMG reference gene:2504120951; PFAM: Helix-turn-helix domain; Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region YP_004256867.1 KEGG: upa:UPA3_0390 multiple banded antigen; SPTR: RNase P protein subunit, RNase MRP protein subunit; IMG reference gene:2504120952 YP_004256868.1 COGs: COG5534 Plasmid replication initiator protein; KEGG: dra:DR_A0369 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120953; PFAM: Replication initiator protein A YP_004256869.1 KEGG: pna:Pnap_4432 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120954 YP_004256870.1 KEGG: plm:Plim_0839 ATPase-like protein involved in DNA repair; SPTR: ATPase-like protein involved in DNA repair; IMG reference gene:2504120955 YP_004256871.1 KEGG: sma:SAV_6933 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120956 YP_004256872.1 KEGG: fsu:Fisuc_0361 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120957 YP_004256873.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027; KEGG: bcv:Bcav_1424 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504120958; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004256874.1 KEGG: see:SNSL254_p_0116 hypothetical protein; SPTR: Putative DNA modification methylase; IMG reference gene:2504120959 YP_004256875.1 KEGG: vcj:VCD_001412 iron-hydroxamate transporter permease subunit; SPTR: Iron(III) ABC transporter, permease protein; IMG reference gene:2504120960 YP_004256876.1 KEGG: dre:406458 solute carrier family 20, member 1a; SPTR: Sodium-dependent phosphate transporter 1-A; IMG reference gene:2504120961; PFAM: Sodium:solute symporter family YP_004256877.1 KEGG: gob:Gobs_1963 peptidase S9 prolyl oligopeptidase active site domain protein; IMG reference gene:2504120962 YP_004256878.1 KEGG: scb:SCAB_80011 putative helicase; SPTR: Putative helicase; IMG reference gene:2504120963 YP_004256879.1 KEGG: oaa:100079337 helicase with zinc finger; SPTR: Putative uncharacterized protein; IMG reference gene:2504120964 YP_004256880.1 KEGG: wch:wcw_0523 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120965 YP_004256881.1 KEGG: tmz:Tmz1t_2445 putative monovalent cation/H+ antiporter subunit A; SPTR: NADH dehydrogenase (Quinone); IMG reference gene:2504120966 YP_004256882.1 KEGG: amd:AMED_6122 dephospho-CoA kinase; SPTR: Dephospho-CoA kinase; IMG reference gene:2504120967 YP_004256883.1 KEGG: rrs:RoseRS_2754 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120968 YP_004256884.1 KEGG: cma:Cmaq_1289 alpha-mannosidase; SPTR: Putative uncharacterized protein; IMG reference gene:2504120969 YP_004256885.1 KEGG: smt:Smal_2459 monooxygenase FAD-binding; SPTR: Monooxygenase FAD-binding; IMG reference gene:2504120970 YP_004256886.1 KEGG: pwa:Pecwa_0332 tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; IMG reference gene:2504120971 YP_004256887.1 KEGG: psl:Psta_2513 hypothetical protein; SPTR: Cytidylyltransferase domain protein; IMG reference gene:2504120972 YP_004256888.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: dge:Dgeo_2967 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504120973; PFAM: UvrD/REP helicase YP_004256889.1 KEGG: dge:Dgeo_1813 GreA/GreB family elongation factor; SPTR: GreA/GreB family elongation factor; IMG reference gene:2504120974; PFAM: Transcription elongation factor, GreA/GreB, C-term YP_004256890.1 KEGG: rsq:Rsph17025_2247 major facilitator transporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504120975 YP_004256891.1 IMG reference gene:2504120976 YP_004256892.1 KEGG: scb:SCAB_33181 putative thioesterase; SPTR: Putative thioesterase; IMG reference gene:2504120977 YP_004256893.1 KEGG: rde:RD1_A0106 RC187; SPTR: RC187; IMG reference gene:2504120978 YP_004256894.1 KEGG: tps:THAPSDRAFT_268857 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120979 YP_004256895.1 KEGG: afr:AFE_1327 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120980 YP_004256896.1 KEGG: sus:Acid_1785 diacylglycerol O-acyltransferase; SPTR: Diacylglycerol O-acyltransferase; IMG reference gene:2504120981 YP_004256897.1 InterPro IPR006442; KEGG: saq:Sare_3026 prevent-host-death family protein; SPTR: Prevent-host-death family protein; TIGRFAM: Prevent-host-death protein; IMG reference gene:2504120982; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004256898.1 KEGG: has:Halsa_0074 hypothetical protein; SPTR: UvrABC system protein C; IMG reference gene:2504120983 YP_004256899.1 KEGG: hmg:100197475 similar to Phosphatidylinositol 3-kinase regulatory subunit alpha; SPTR: Cell division protein Smc; IMG reference gene:2504120984 YP_004256900.1 KEGG: rpc:RPC_3925 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120985; PFAM: Protein of unknown function (DUF2384) YP_004256901.1 InterPro IPR014914; KEGG: rec:RHECIAT_PA0000066 hypothetical protein; PFAM: RES; SMART: RES; SPTR: Hypothetical conserved protein; IMG reference gene:2504120986; PFAM: RES domain YP_004256902.1 KEGG: vei:Veis_3977 dihydrolipoamide dehydrogenase; SPTR: Dihydrolipoamide dehydrogenase; IMG reference gene:2504120987 YP_004256903.1 COGs: COG1651 Protein-disulfide isomerase; InterPro IPR001853; KEGG: hau:Haur_3286 DsbA oxidoreductase; PFAM: DSBA-like thioredoxin domain; SPTR: DSBA oxidoreductase; IMG reference gene:2504120993; PFAM: DSBA-like thioredoxin domain YP_004256904.1 COGs: COG2217 Cation transport ATPase; InterPro IPR006121:IPR008250:IPR005834:IPR006404:IPR006416:IPR0017 57; KEGG: dra:DR_A0073 cation-transporting P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Cation-transporting P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504120994; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004256905.1 KEGG: scl:sce8712 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120995; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family YP_004256906.1 COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109; KEGG: dra:DR_A0072 hypothetical protein; PFAM: Glutaredoxin; SPTR: Putative uncharacterized protein; IMG reference gene:2504120996; PFAM: Glutaredoxin YP_004256907.1 COGs: COG1230 Co/Zn/Cd efflux system component; InterPro IPR002524; KEGG: dge:Dgeo_0215 cation diffusion facilitator family transporter; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; IMG reference gene:2504120997; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004256908.1 COGs: COG1999 Uncharacterized protein SCO1/SenC/PrrC involved in biogenesis of respiratory and photosynthetic systems; InterPro IPR003782; KEGG: dge:Dgeo_0582 electron transport protein SCO1/SenC; PFAM: Copper chaperone SCO1/SenC; SPTR: Electron transport protein SCO1/SenC; IMG reference gene:2504120998; PFAM: SCO1/SenC YP_004256909.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: dra:DR_A0071 transcriptional repressor SmtB; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional repressor SmtB; IMG reference gene:2504120999; PFAM: Bacterial regulatory protein, arsR family YP_004256910.1 KEGG: dge:Dgeo_1591 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121000 YP_004256911.1 COGs: COG1742 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0060; InterPro IPR003844; KEGG: hau:Haur_1798 hypothetical protein; PFAM: Uncharacterised protein family UPF0060; SPTR: UPF0060 membrane protein Haur_1798; IMG reference gene:2504121001; PFAM: Uncharacterised BCR, YnfA/UPF0060 family YP_004256912.1 COGs: COG3798 conserved hypothetical protein; InterPro IPR018684; KEGG: dra:DR_1348 hypothetical protein; PFAM: Protein of unknown function DUF2171; SPTR: Putative uncharacterized protein; IMG reference gene:2504121002; PFAM: Uncharacterized protein conserved in bacteria (DUF2171) YP_004256913.1 InterPro IPR002559; KEGG: dge:Dgeo_2659 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4; IMG reference gene:2504121004; PFAM: Transposase DDE domain YP_004256914.1 KEGG: dge:Dgeo_2285 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121005 YP_004256915.1 KEGG: rlg:Rleg_5307 sodium/hydrogen exchanger; SPTR: Putative transmembrane Na+/H+ antiporter; IMG reference gene:2504121006 YP_004256916.1 KEGG: cme:CMC171C similar to ATP-dependent RNA helicase A; SPTR: Putative regulatory protein; IMG reference gene:2504121007 YP_004256917.1 KEGG: lif:LinJ01.0310 acidocalcisomal exopolyphosphatase; SPTR: Acidocalcisomal exopolyphosphatase, putative; IMG reference gene:2504121008 YP_004256918.1 KEGG: cwo:Cwoe_3038 phytanoyl-CoA dioxygenase; SPTR: Phytanoyl-CoA dioxygenase; IMG reference gene:2504121009 YP_004256919.1 KEGG: cpi:Cpin_2644 major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504121010 YP_004256920.1 KEGG: cti:RALTA_B0991 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504121011 YP_004256921.1 COGs: COG1637 nuclease of the RecB family; HAMAP: Uncharacterised protein family UPF0286; InterPro IPR002793; KEGG: ton:TON_1648 hypothetical protein; PFAM: Uncharacterised protein family UPF0286; SPTR: UPF0286 protein TON_1648; IMG reference gene:2504121012; PFAM: Protein of unknown function DUF91 YP_004256922.1 COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR001279:IPR011108; KEGG: hau:Haur_5264 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; RNA-metabolising metallo-beta-lactamase; SMART: Beta-lactamase-like; SPTR: Beta-lactamase domain protein; IMG reference gene:2504121014; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain YP_004256923.1 KEGG: ppw:PputW619_1725 transmembrane pair domain-containing protein; SPTR: Transmembrane pair domain protein; IMG reference gene:2504121015 YP_004256924.1 InterPro IPR012902; KEGG: dra:DR_0546 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121016; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004256925.1 KEGG: hau:Haur_2414 AMP-dependent synthetase and ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121017 YP_004256926.1 KEGG: kfl:Kfla_3930 transcriptional regulator, MarR family; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504121018 YP_004256927.1 KEGG: dge:Dgeo_2953 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121019 YP_004256928.1 COGs: COG2389 Uncharacterized metal-binding protein; InterPro IPR019250; KEGG: tth:TTC1821 hypothetical protein; PFAM: Protein of unknown function DUF2227, metal-binding; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504121020; PFAM: Uncharacterized metal-binding protein (DUF2227) YP_004256929.1 COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482; KEGG: mrb:Mrub_0949 type II secretion system protein E; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SPTR: Type II secretion system protein E; IMG reference gene:2504121021; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein YP_004256930.1 COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR001482:IPR006321:IPR003593; KEGG: tra:Trad_2339 twitching motility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504121022; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT YP_004256931.1 KEGG: gau:GAU_3868 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121023 YP_004256932.1 KEGG: mrb:Mrub_2741 hypothetical protein; SPTR: Type IV pilus assembly protein PilO; IMG reference gene:2504121024; PFAM: Pilus assembly protein, PilO YP_004256933.1 KEGG: cbr:CBG02561 Hypothetical protein CBG02561; SPTR: Putative uncharacterized protein; IMG reference gene:2504121025 YP_004256934.1 COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR005644:IPR004846; KEGG: msv:Mesil_3590 type II and III secretion system protein; PFAM: Type II/III secretion system; NolW-like; SPTR: Type II and III secretion system protein; IMG reference gene:2504121026; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein YP_004256935.1 KEGG: tbi:Tbis_2149 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121027 YP_004256936.1 COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: hor:Hore_05990 Tfp pilus biogenesis protein PilC; PFAM: Type II secretion system F domain; SPTR: Tfp pilus biogenesis protein PilC; IMG reference gene:2504121028; PFAM: Bacterial type II secretion system protein F domain YP_004256937.1 InterPro IPR012902; KEGG: mrb:Mrub_0898 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121029; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004256938.1 InterPro IPR012902; KEGG: bbt:BBta_1281 putative general secretion pathway protein H, GspH; SPTR: Putative General secretion pathway protein H, GspH; IMG reference gene:2504121030; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004256939.1 InterPro IPR012902; KEGG: ade:Adeh_0629 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121031; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004256940.1 KEGG: cel:T19D12.1 hypothetical protein; SPTR: Flagellin; IMG reference gene:2504121032 YP_004256941.1 InterPro IPR012902; KEGG: gau:GAU_0582 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121033 YP_004256942.1 InterPro IPR000424; KEGG: mva:Mvan_2127 hypothetical protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; IMG reference gene:2504121034; PFAM: Single-strand binding protein family YP_004256943.1 InterPro IPR014044; KEGG: vcn:VOLCADRAFT_116567 hypothetical protein; PFAM: CAP domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504121035; PFAM: Cysteine-rich secretory protein family YP_004256944.1 KEGG: aga:AgaP_AGAP008698 AGAP008698-PA; SPTR: Non-alpha nicotinic acetylcholine receptor subunit; IMG reference gene:2504121036 YP_004256945.1 KEGG: dwi:Dwil_GK24476 GK24476 gene product from transcript GK24476-RA; SPTR: GK24476; IMG reference gene:2504121037 YP_004256946.1 InterPro IPR000182; KEGG: bgl:bglu_3p1380 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504121038; PFAM: Acetyltransferase (GNAT) family YP_004256947.1 KEGG: nfi:NFIA_008980 bZIP transcription factor, putative; SPTR: Putative uncharacterized protein; IMG reference gene:2504121039 YP_004256948.1 KEGG: lpf:lpl0421 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121040 YP_004256949.1 KEGG: mno:Mnod_7132 protein tyrosine phosphatase; SPTR: Dual specificity phosphatase, catalytic domain, putative; IMG reference gene:2504121041 YP_004256950.1 KEGG: dge:Dgeo_2497 hypothetical protein; SPTR: Plasmid replication initiator repA-related protein; IMG reference gene:2504121042; PFAM: Replication initiator protein A YP_004256951.1 KEGG: bta:506059 acyl-CoA synthetase long-chain family member 6; SPTR: Acyl-CoA synthetase long-chain family member 6; IMG reference gene:2504121043 YP_004256952.1 KEGG: hor:Hore_21570 phosphate ABC transporter, inner membrane subunit PstC; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; IMG reference gene:2504121044 YP_004256953.1 KEGG: bcm:Bcenmc03_1304 iron-hydroxamate transporter permease subunit; SPTR: Transport system permease protein; IMG reference gene:2504121045 YP_004256954.1 KEGG: tcu:Tcur_4516 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121046 YP_004256955.1 InterPro IPR005074; KEGG: dge:Dgeo_1490 peptidase C39, bacteriocin processing; PFAM: Peptidase C39, bacteriocin processing; SPTR: Peptidase C39; IMG reference gene:2504121047; PFAM: Peptidase C39 family YP_004256956.1 KEGG: dvi:Dvir_GJ19150 GJ19150 gene product from transcript GJ19150-RA; SPTR: GJ19150; IMG reference gene:2504121048 YP_004256957.1 KEGG: hoh:Hoch_2353 hypothetical protein; SPTR: Acidic endopolygalacturonase 3; IMG reference gene:2504121049 YP_004256958.1 InterPro IPR001867; KEGG: tcu:Tcur_1985 putative phytochrome sensor protein; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504121050 YP_004256959.1 KEGG: fma:FMG_P0159 hypothetical protein; IMG reference gene:2504121051 YP_004256960.1 KEGG: dge:Dgeo_3092 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121052 YP_004256961.1 KEGG: dge:Dgeo_3091 general secretion pathway protein E; SPTR: Surfactin synthetase B; IMG reference gene:2504121053 YP_004256962.1 KEGG: ter:Tery_1496 chromosome segregation ATPase-like protein; SPTR: Endopeptidase LytF; IMG reference gene:2504121054 YP_004256963.1 InterPro IPR015330; KEGG: dge:Dgeo_3090 bifunctional DNA primase/polymerase; PFAM: DNA primase/polymerase, bifunctional, N-terminal; SMART: DNA primase/polymerase, bifunctional, N-terminal; SPTR: Bifunctional DNA primase/polymerase; IMG reference gene:2504121055; PFAM: Bifunctional DNA primase/polymerase, N-terminal YP_004256964.1 KEGG: elm:ELI_0389 peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Dehydrogenase; IMG reference gene:2504121056 YP_004256965.1 KEGG: ppp:PHYPADRAFT_83863 hypothetical protein; SPTR: Outer membrane protein, OMP85 family; IMG reference gene:2504121057 YP_004256966.1 KEGG: reu:Reut_B3820 argininosuccinate lyase; SPTR: Spindle assembly checkpoint component MAD1; IMG reference gene:2504121058 YP_004256967.1 KEGG: gpb:HDN1F_08990 putative beta-ketoacyl synthase; SPTR: Putative beta-ketoacyl synthase; IMG reference gene:2504121059 YP_004256968.1 COGs: COG3236 conserved hypothetical protein; InterPro IPR012816; KEGG: mru:mru_1967 hypothetical protein; PFAM: Conserved hypothetical protein CHP02464; SPTR: NH(3)-dependent NAD(+) synthetase; TIGRFAM: Conserved hypothetical protein CHP02464; IMG reference gene:2504121060; PFAM: Domain of unknown function (DUF1768); Protein of unknown function (DUF1273); TIGRFAM: conserved hypothetical protein, ribA/ribD-fused YP_004256969.1 InterPro IPR007627; KEGG: bcv:Bcav_0544 glycoside hydrolase family 16; PFAM: RNA polymerase sigma-70 region 2; SPTR: UvrD/REP helicase; IMG reference gene:2504121061 YP_004256970.1 KEGG: adg:Adeg_0207 agmatinase; SPTR: Agmatinase; IMG reference gene:2504121062 YP_004256971.1 KEGG: mcc:709409 spindle and centriole associated protein 1; SPTR: Bromodomain-containing protein, putative; IMG reference gene:2504121063 YP_004256972.1 KEGG: pjd:Pjdr2_0886 cell wall/surface repeat protein; SPTR: Cell wall/surface repeat protein; IMG reference gene:2504121064 YP_004256973.1 KEGG: dge:Dgeo_2953 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121065 YP_004256974.1 KEGG: plm:Plim_3603 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504121066 YP_004256975.1 KEGG: msv:Mesil_0500 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121067 YP_004256976.1 KEGG: dge:Dgeo_2956 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121068 YP_004256977.1 KEGG: ara:Arad_3428 hemin transport system; SPTR: Hemin transport system; IMG reference gene:2504121069 YP_004256978.1 KEGG: ptm:GSPATT00038503001 hypothetical protein; SPTR: Glycosyl hydrolase; IMG reference gene:2504121070 YP_004256979.1 KEGG: dge:Dgeo_2948 type IV secretory pathway VirB4 component, ATPase TraC; SPTR: Type IV secretory pathway VirB4 component, ATPase TRAC; IMG reference gene:2504121071 YP_004256980.1 KEGG: dac:Daci_2082 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121072 YP_004256981.1 KEGG: dge:Dgeo_2950 TrbL/VirB6 plasmid conjugal transfer protein; SPTR: TrbL/VirB6 plasmid conjugal transfer protein; IMG reference gene:2504121073 YP_004256982.1 COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR003688; KEGG: dge:Dgeo_2951 ATPase involved in conjugal plasmid transfer TraG; PFAM: Ti-type conjugative transfer system, TraG-like; SPTR: ATPase involved in conjugal plasmid transfer TRAG; IMG reference gene:2504121074; PFAM: TraG/TraD family YP_004256983.1 COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR001604:IPR020821; KEGG: ddr:Deide_1p00121 putative DNA/RNA endonuclease G; PFAM: DNA/RNA non-specific endonuclease; SMART: DNA/RNA non-specific endonuclease; Extracellular Endonuclease, subunit A; SPTR: Putative DNA/RNA endonuclease G; IMG reference gene:2504121075; PFAM: DNA/RNA non-specific endonuclease YP_004256984.1 KEGG: hth:HTH_0614 replicative DNA helicase; SPTR: Replicative DNA helicase; IMG reference gene:2504121076 YP_004256985.1 COGs: COG3973 Superfamily I DNA and RNA helicase; KEGG: ddr:Deide_17480 putative UvrD/rep helicase family protein; SPTR: Putative uvrD/rep helicase family protein; IMG reference gene:2504121077 YP_004256986.1 KEGG: tbd:Tbd_2605 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121078 YP_004256987.1 InterPro IPR010093; KEGG: nda:Ndas_5007 DNA binding domain protein, excisionase family; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: Excisionase/Xis, DNA-binding; IMG reference gene:2504121079; TIGRFAM: DNA binding domain, excisionase family YP_004256988.1 KEGG: saq:Sare_1016 hypothetical protein; SPTR: ABC transporter, permease protein; IMG reference gene:2504121080 YP_004256989.1 KEGG: lbl:LBL_1628 signal peptide peptidase (protease IV); SPTR: Hsp90-like protein; IMG reference gene:2504121081 YP_004256990.1 COGs: COG3854 conserved hypothetical protein; KEGG: dge:Dgeo_2960 AAA ATPase; SPTR: AAA ATPase; manually curated; IMG reference gene:2504121082; TIGRFAM: stage III sporulation protein AA YP_004256991.1 KEGG: bfo:BRAFLDRAFT_86776 hypothetical protein; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504121083 YP_004256992.1 KEGG: sco:SCO2857 membrane protein; SPTR: Putative membrane protein; IMG reference gene:2504121084 YP_004256993.1 KEGG: lif:LinJ34.3420 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121085 YP_004256994.1 KEGG: tgr:Tgr7_0800 protein of unknown function DUF1538; SPTR: Putative uncharacterized protein; IMG reference gene:2504121086 YP_004256995.1 KEGG: lif:LinJ34.1180 hypothetical protein; SPTR: Protein phosphatase 2c; IMG reference gene:2504121087 YP_004256996.1 KEGG: cfa:485044 ankyrin repeat domain 24; SPTR: Ankyrin repeat domain-containing protein 24; IMG reference gene:2504121088 YP_004256997.1 InterPro IPR001867; KEGG: tcu:Tcur_1985 putative phytochrome sensor protein; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative phytochrome sensor protein; IMG reference gene:2504120745 YP_004256998.1 KEGG: caa:Caka_0701 galactokinase; SPTR: Galactokinase; IMG reference gene:2504120746 YP_004256999.1 InterPro IPR007159; KEGG: sus:Acid_2533 transcriptional regulator/antitoxin, MazE; PFAM: Transcription regulator AbrB/SpoV, predicted; SMART: Transcription regulator AbrB/SpoV, predicted; SPTR: Transcriptional regulator/antitoxin, MazE; IMG reference gene:2504120747; PFAM: SpoVT / AbrB like domain YP_004257000.1 COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: xac:XACa0027 plasmid stable inheritance protein K; PFAM: PemK-like protein; SPTR: Transcriptional modulator of MazE/toxin, MazF; IMG reference gene:2504120748; PFAM: PemK-like protein YP_004257001.1 KEGG: tml:GSTUM_00002171001 hypothetical protein; SPTR: Whole genome shotgun sequence assembly, scaffold_122, strain Mel28; IMG reference gene:2504120749 YP_004257002.1 InterPro IPR005074; KEGG: ddr:Deide_09600 putative peptidase C39, bacteriocin processing; PFAM: Peptidase C39, bacteriocin processing; SPTR: Putative Peptidase C39, bacteriocin processing; IMG reference gene:2504120750; PFAM: Peptidase C39 family YP_004257003.1 COGs: COG5642 conserved hypothetical protein; InterPro IPR011979; KEGG: srm:SRM_00237 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP02293; IMG reference gene:2504120751; PFAM: Protein of unknown function (DUF2384); TIGRFAM: putative toxin-antitoxin system antitoxin component, TIGR02293 family YP_004257004.1 InterPro IPR014914; KEGG: srm:SRM_02872 hypothetical protein; PFAM: RES; SMART: RES; SPTR: Putative uncharacterized protein; IMG reference gene:2504120752; PFAM: RES domain YP_004257005.1 KEGG: esi:Exig_1923 serine/threonine protein kinase with PASTA sensor(s); SPTR: Putative uncharacterized protein; IMG reference gene:2504120753 YP_004257006.1 KEGG: tcu:Tcur_4516 hypothetical protein; SPTR: Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; IMG reference gene:2504120754 YP_004257007.1 KEGG: hje:HacjB3_16506 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120755 YP_004257008.1 KEGG: ddr:Deide_06570 putative transposase; SPTR: Putative transposase; IMG reference gene:2504120756 YP_004257009.1 COGs: COG5504 Zn-dependent protease; InterPro IPR018728; KEGG: msv:Mesil_2664 protein of unknown function DUF2268, Zn-dependent protease-related protein; PFAM: Protein of unknown function DUF2268, Zn-dependent protease-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504120757; PFAM: Predicted Zn-dependent protease (DUF2268) YP_004257010.1 InterPro IPR001845; KEGG: cfl:Cfla_3541 hypothetical protein; SMART: HTH transcriptional regulator, ArsR; SPTR: Putative uncharacterized protein; IMG reference gene:2504120758 YP_004257011.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sto:ST1034 heme exporter protein A; PFAM: ABC transporter-like; PRIAM: Heme-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: 266aa long hypothetical heme exporter protein A; IMG reference gene:2504120759; PFAM: ABC transporter YP_004257012.1 KEGG: xce:Xcel_1354 ABC-2 type transporter; SPTR: ABC-type transport system protein; IMG reference gene:2504120760 YP_004257013.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR015358; KEGG: sco:SCO0407 transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; Transcription regulator MerR, DNA binding; SMART: HTH transcriptional regulator, MerR; SPTR: Putative transcriptional regulator; IMG reference gene:2504120761; PFAM: MerR, DNA binding; MerR family regulatory protein YP_004257014.1 InterPro IPR001584; KEGG: tin:Tint_1581 integrase catalytic region; PFAM: Integrase, catalytic core; SPTR: Integrase catalytic region; manually curated; IMG reference gene:2504120762; PFAM: Integrase core domain YP_004257015.1 InterPro IPR002514; KEGG: mlu:Mlut_18320 hypothetical protein; PFAM: Transposase IS3/IS911family; SPTR: Putative uncharacterized protein; IMG reference gene:2504120763; PFAM: Transposase YP_004257016.1 COGs: COG3972 Superfamily I DNA and RNA helicase; InterPro IPR011528; KEGG: bca:BCE_1013 hypothetical protein; PFAM: NERD; SPTR: Pentapeptide repeat protein; IMG reference gene:2504120764; PFAM: Nuclease-related domain YP_004257017.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: dge:Dgeo_0554 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Extracellular solute-binding protein, family 5; IMG reference gene:2504120765; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004257018.1 KEGG: oan:Oant_3801 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120766 YP_004257019.1 KEGG: nvi:100123496 hypothetical protein LOC100123496; SPTR: Succinylglutamate desuccinylase/aspartoacylase; IMG reference gene:2504120768 YP_004257020.1 COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR001604:IPR020821; KEGG: ddr:Deide_1p00121 putative DNA/RNA endonuclease G; PFAM: DNA/RNA non-specific endonuclease; SMART: DNA/RNA non-specific endonuclease; Extracellular Endonuclease, subunit A; SPTR: Putative DNA/RNA endonuclease G; IMG reference gene:2504120770; PFAM: DNA/RNA non-specific endonuclease YP_004257021.1 COGs: COG3973 Superfamily I DNA and RNA helicase; KEGG: dra:DR_1572 helicase-related protein; SPTR: Putative uvrD/rep helicase family protein; IMG reference gene:2504120771 YP_004257022.1 COGs: COG3973 Superfamily I DNA and RNA helicase; KEGG: ddr:Deide_17480 putative UvrD/rep helicase family protein; SPTR: Putative uvrD/rep helicase family protein; IMG reference gene:2504120772; PFAM: UvrD/REP helicase YP_004257023.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119; KEGG: eta:ETA_pET460080 resolvase; PFAM: Resolvase, N-terminal; SMART: Resolvase, N-terminal; SPTR: Resolvase; IMG reference gene:2504120773; PFAM: Resolvase, N terminal domain YP_004257024.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: sen:SACE_4542 BadM/Rrf2 family transcriptional regulator; PFAM: Transcription regulator Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcription regulator Rrf2; IMG reference gene:2504120774; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004257025.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020842; KEGG: kfl:Kfla_5670 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase; IMG reference gene:2504120775; PFAM: short chain dehydrogenase YP_004257026.1 COGs: COG0259 Pyridoxamine-phosphate oxidase; InterPro IPR011576:IPR019576; KEGG: dge:Dgeo_0443 pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal; PRIAM: Pyridoxal 5'-phosphate synthase; SPTR: Pyridoxine/pyridoxamine 5'-phosphate oxidase; IMG reference gene:2504120776; PFAM: Pyridoxamine 5'-phosphate oxidase; Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; TIGRFAM: pyridoxamine-phosphate oxidase YP_004257027.1 COGs: COG3335 Transposase and inactivated derivatives; KEGG: dra:DR_2425 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120778 YP_004257028.1 COGs: COG3293 Transposase and inactivated derivatives; InterPro IPR002559; KEGG: azl:AZL_027290 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase; IMG reference gene:2504120780; PFAM: Transposase DDE domain YP_004257029.1 InterPro IPR002559; KEGG: dra:DR_B0117 transposase, putative; PFAM: Transposase, IS4-like; SPTR: Transposase, putative; IMG reference gene:2504120781; PFAM: Transposase DDE domain YP_004257030.1 InterPro IPR001584; KEGG: tin:Tint_1581 integrase catalytic region; PFAM: Integrase, catalytic core; SPTR: Integrase catalytic region; IMG reference gene:2504120782; PFAM: Integrase core domain YP_004257031.1 InterPro IPR002514; KEGG: mlu:Mlut_18320 hypothetical protein; PFAM: Transposase IS3/IS911family; SPTR: Transposase IS3/IS911 family protein; IMG reference gene:2504120783; PFAM: Transposase YP_004257032.1 KEGG: tth:TTC1362 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120784 YP_004257033.1 KEGG: amr:AM1_3959 hypothetical protein; SPTR: Flagellar basal body FlaE domain protein; IMG reference gene:2504120785 YP_004257034.1 COGs: COG3544 conserved hypothetical protein; InterPro IPR005183; KEGG: ddr:Deide_2p01090 hypothetical protein; PFAM: Domain of unknown function DUF305; SPTR: Putative uncharacterized protein; IMG reference gene:2504120786; PFAM: Domain of unknown function (DUF305) YP_004257035.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ddr:Deide_2p01080 putative response regulator, OmpR; putative phosphate regulon transcriptional regulatory protein PhoB; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Putative response regulator, OmpR; putative phosphate regulon transcriptional regulatory protein phoB; IMG reference gene:2504120787; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004257036.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: dge:Dgeo_2597 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2504120788; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004257037.1 InterPro IPR005560; KEGG: dge:Dgeo_0085 hypothetical protein; SPTR: Ferredoxin-like protein, DUF326; IMG reference gene:2504120789 YP_004257038.1 COGs: COG3316 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: dge:Dgeo_3086 transposase; PFAM: Integrase, catalytic core; SPTR: Transposase; IMG reference gene:2504120790; PFAM: Transposase IS66 family YP_004257039.1 COGs: COG3544 conserved hypothetical protein; InterPro IPR005183; KEGG: dge:Dgeo_0086 hypothetical protein; PFAM: Domain of unknown function DUF305; SPTR: Putative uncharacterized protein; IMG reference gene:2504120792; PFAM: Domain of unknown function (DUF305) YP_004257040.1 InterPro IPR018777; KEGG: ddr:Deide_1p01800 putative plasmid replication initiator protein; PFAM: Replication initiator protein A; SPTR: Putative plasmid replication initiator protein; IMG reference gene:2504120795; PFAM: Replication initiator protein A YP_004257041.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: dge:Dgeo_2494 ParB-like partition proteins; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein; IMG reference gene:2504120796; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004257042.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: dra:DR_A0001 ParA family chromosome partitioning ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Chromosome partitioning ATPase, putative, ParA family; IMG reference gene:2504120797; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004257043.1 KEGG: dra:DR_1535 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120798 YP_004257044.1 COGs: COG3372 conserved hypothetical protein; InterPro IPR008508; KEGG: ddr:Deide_17310 hypothetical protein; PFAM: Protein of unknown function DUF790, endonuclease-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504120799; PFAM: Protein of unknown function (DUF790) YP_004257045.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935:IPR001650:IPR014001; KEGG: ddr:Deide_17320 putative bifunctional protein: helicase type III restriction enzyme/DEAD/DEAH box helicase; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Putative bifunctional protein: Helicase Type III restriction enzyme/ DEAD/DEAH box helicase; manually curated; IMG reference gene:2504120800; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit YP_004257046.1 COGs: COG3335 Transposase and inactivated derivatives; KEGG: dra:DR_2425 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504120802 YP_004257047.1 COGs: COG3544 conserved hypothetical protein; InterPro IPR005183; KEGG: ddr:Deide_2p01090 hypothetical protein; PFAM: Domain of unknown function DUF305; SPTR: Putative uncharacterized protein; IMG reference gene:2504120805; PFAM: Domain of unknown function (DUF305) YP_004257048.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ddr:Deide_2p01080 putative response regulator, OmpR; putative phosphate regulon transcriptional regulatory protein PhoB; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Putative response regulator, OmpR; putative phosphate regulon transcriptional regulatory protein phoB; IMG reference gene:2504120806; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004257049.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: dge:Dgeo_2597 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2504120807; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004257050.1 COGs: COG2217 Cation transport ATPase; InterPro IPR008250:IPR005834:IPR006403:IPR006416:IPR001757; KEGG: dge:Dgeo_2575 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504120808; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004257051.1 COGs: COG1662 Transposase and inactivated derivatives IS1 family; InterPro IPR005063; KEGG: dge:Dgeo_3100 IS1 transposase; PFAM: Transposase, IS1; SPTR: IS1 transposase; manually curated; IMG reference gene:2504120809; PFAM: IS1 transposase YP_004257052.1 InterPro IPR003220; KEGG: srm:SRM_00776 insertion element; PFAM: Insertion element protein; SPTR: Insertion element protein; manually curated; IMG reference gene:2504120810; PFAM: Insertion element protein YP_004257053.1 InterPro IPR002559; KEGG: dge:Dgeo_2989 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein; manually curated; IMG reference gene:2504120812; PFAM: Transposase DDE domain YP_004257054.1 InterPro IPR013568; KEGG: rba:RB4106 hypothetical protein; PFAM: SEFIR; SPTR: Putative uncharacterized protein; IMG reference gene:2504120813; PFAM: SEFIR domain YP_004257055.1 KEGG: spc:Sputcn32_2912 HsdR family type I site-specific deoxyribonuclease; SPTR: Putative uncharacterized protein; IMG reference gene:2504120814 YP_004257056.1 KEGG: lpp:lpp0150 SdhB protein, substrate of the Dot/Icm system; SPTR: SdhB protein, substrate of the Dot/Icm system; IMG reference gene:2504120815 YP_004257057.1 KEGG: dol:Dole_1478 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120816 YP_004257058.1 InterPro IPR018841; KEGG: mag:amb1637 hypothetical protein; PFAM: Protein of unknown function DUF2442; SPTR: Putative uncharacterized protein; IMG reference gene:2504120817; PFAM: Protein of unknown function (DUF2442) YP_004257059.1 InterPro IPR014883; KEGG: prw:PsycPRwf_1331 VRR-NUC; PFAM: VRR-NUC; SPTR: VRR-NUC; IMG reference gene:2504120818; PFAM: VRR-NUC domain YP_004257060.1 KEGG: axy:AXYL_06794 DNA/RNA non-specific endonuclease family protein 2; SPTR: Chromosome 12 SCAF15104, whole genome shotgun sequence.; IMG reference gene:2504120819 YP_004257061.1 KEGG: sgr:SGR_831 hypothetical protein; SPTR: Chromosome 1 SCAF14609, whole genome shotgun sequence; IMG reference gene:2504120820 YP_004257062.1 KEGG: ami:Amir_4498 amino acid adenylation domain protein; SPTR: Amino acid adenylation domain protein; IMG reference gene:2504120821 YP_004257063.1 KEGG: ckr:CKR_P19 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120822 YP_004257064.1 KEGG: adg:Adeg_0703 primosome, DnaD subunit; SPTR: Primosome, DnaD subunit; IMG reference gene:2504120823 YP_004257065.1 KEGG: smt:Smal_3782 Mg chelatase, subunit ChlI; SPTR: Mg chelatase, subunit ChlI; IMG reference gene:2504120824 YP_004257066.1 COGs: COG3561 Phage anti-repressor protein; InterPro IPR013557:IPR005039; KEGG: bhe:BH03240 anti-repressor protein; PFAM: AntA/AntB antirepressor; Phage antirepressor protein; SPTR: Phage protein; IMG reference gene:2504120825; PFAM: AntA/AntB antirepressor; Phage antirepressor protein KilAC domain YP_004257067.1 COGs: COG3654 Prophage maintenance system killer protein; InterPro IPR003812:IPR006440; KEGG: pcu:pc1473 doc (death on cure) protein of bacteriophage P1; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Death-on-curing family protein; TIGRFAM: Death-on-curing protein; IMG reference gene:2504120827; PFAM: Fic/DOC family; TIGRFAM: death-on-curing family protein YP_004257068.1 KEGG: sli:Slin_5456 transcriptional regulator/antitoxin, MazE; SPTR: Transcriptional regulator/antitoxin, MazE; IMG reference gene:2504120828 YP_004257069.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119:IPR006120; KEGG: cak:Caul_5459 resolvase domain-containing protein; PFAM: Resolvase, N-terminal; Resolvase, helix-turn-helix domain; SMART: Resolvase, N-terminal; SPTR: Resolvase domain; IMG reference gene:2504120829; PFAM: Resolvase, N terminal domain; Helix-turn-helix domain of resolvase YP_004257070.1 InterPro IPR002559; KEGG: ddr:Deide_3p01971 putative transposase; PFAM: Transposase, IS4-like; SPTR: Putative transposase; IMG reference gene:2504120831; PFAM: Transposase DDE domain YP_004257071.1 InterPro IPR003675; KEGG: cfl:Cfla_3234 abortive infection protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein; IMG reference gene:2504120834; PFAM: CAAX amino terminal protease family YP_004257072.1 COGs: COG0262 Dihydrofolate reductase; InterPro IPR002734; KEGG: pfl:PFL_3631 riboflavin biosynthesis protein RibD domain-containing protein; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: RibD C-terminal domain; IMG reference gene:2504120835; PFAM: RibD C-terminal domain YP_004257073.1 KEGG: dra:DR_0404 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120836 YP_004257074.1 KEGG: dpe:Dper_GL18814 GL18814 gene product from transcript GL18814-RA; SPTR: GL18814; IMG reference gene:2504120837 YP_004257075.1 KEGG: bdu:BDU_4017 plasmid partionning associated protein 2; SPTR: Plasmid partionning associated protein 2; IMG reference gene:2504120838 YP_004257076.1 KEGG: acr:Acry_1588 methyl-accepting chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis sensory transducer; IMG reference gene:2504120839 YP_004257077.1 InterPro IPR002514; KEGG: mlu:Mlut_18320 hypothetical protein; PFAM: Transposase IS3/IS911family; SPTR: Putative uncharacterized protein; IMG reference gene:2504120840; PFAM: Transposase YP_004257078.1 InterPro IPR002559; KEGG: dge:Dgeo_2989 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein; manually curated; IMG reference gene:2504120842; PFAM: Transposase DDE domain YP_004257079.1 COGs: COG2801 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: ddr:Deide_16851 putative transposase; PFAM: Integrase, catalytic core; SPTR: Putative transposase; IMG reference gene:2504120843; PFAM: Integrase core domain YP_004257080.1 InterPro IPR002514; KEGG: ddr:Deide_2p00880 putative transposase; PFAM: Transposase IS3/IS911family; SPTR: Putative transposase; IMG reference gene:2504120844; PFAM: Transposase YP_004257081.1 InterPro IPR002109; KEGG: pag:PLES_26391 glutaredoxin; PFAM: Glutaredoxin; SPTR: Glutaredoxin; IMG reference gene:2504120845; PFAM: Glutaredoxin YP_004257082.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: dge:Dgeo_0091 hypothetical protein; PFAM: Protein of unknown function DUF156; SPTR: Putative uncharacterized protein; IMG reference gene:2504120846; PFAM: Uncharacterised BCR, COG1937 YP_004257083.1 InterPro IPR002559; KEGG: dra:DR_B0117 transposase, putative; PFAM: Transposase, IS4-like; SPTR: Transposase, putative; IMG reference gene:2504120848; PFAM: Transposase DDE domain YP_004257084.1 InterPro IPR001647; KEGG: spe:Spro_4739 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulatory protein; IMG reference gene:2504120849; PFAM: Bacterial regulatory proteins, tetR family YP_004257085.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: oca:OCAR_6881 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504120850; PFAM: Binding-protein-dependent transport system inner membrane component YP_004257086.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: pap:PSPA7_2931 hypothetical protein; SPTR: ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic component; IMG reference gene:2504120851; PFAM: NMT1/THI5 like YP_004257087.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ppf:Pput_2096 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Taurine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504120852; PFAM: ABC transporter YP_004257088.1 COGs: COG1960 Acyl-CoA dehydrogenase; KEGG: oca:OCAR_6878 acyl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase; IMG reference gene:2504120853; PFAM: Acyl-CoA dehydrogenase, N-terminal domain YP_004257089.1 COGs: COG2128 conserved hypothetical protein; InterPro IPR003779; KEGG: pau:PA14_34460 hypothetical protein; PFAM: Carboxymuconolactone decarboxylase; SPTR: Putative uncharacterized protein; IMG reference gene:2504120854; PFAM: Carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain YP_004264015.1 COGs: COG1135 ABC-type metal ion transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ddr:Deide_22360 putative ABC transporter, ATP-binding component; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative ABC transporter, ATP-binding component; IMG reference gene:2504121089; PFAM: ABC transporter YP_004264016.1 COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR000515; KEGG: dra:DR_1357 ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, permease protein; IMG reference gene:2504121090; PFAM: Binding-protein-dependent transport system inner membrane component YP_004264017.1 COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: dra:DR_1358 outer membrane protein; PFAM: NLPA lipoprotein; SPTR: Outer membrane protein; IMG reference gene:2504121091; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family YP_004264018.1 COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: dra:DR_1359 outer membrane protein; PFAM: NLPA lipoprotein; SPTR: Outer membrane protein; IMG reference gene:2504121092; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family YP_004264019.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019949:IPR016048; KEGG: dra:DR_A0120 hypothetical protein; PFAM: Luciferase-like, subgroup; SPTR: Putative uncharacterized protein; TIGRFAM: Luciferase family oxidoreductase, group 1; IMG reference gene:2504121093; PFAM: Luciferase-like monooxygenase; TIGRFAM: luciferase family oxidoreductase, group 1 YP_004264020.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dra:DR_B0093 GGDEF family protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF family protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504121094; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004264021.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: ddr:Deide_3p01910 putative hemolysin; putative membrane protein; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: Putative hemolysin; putative membrane protein; IMG reference gene:2504121095; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004264022.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: ddr:Deide_3p01900 putative hemolysin; putative membrane protein; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SPTR: Putative hemolysin; putative membrane protein; IMG reference gene:2504121096; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004264023.1 COGs: COG2899 conserved hypothetical protein; InterPro IPR007427; KEGG: dra:DR_2226 hypothetical protein; PFAM: Protein of unknown function DUF475; SPTR: Putative uncharacterized protein; IMG reference gene:2504121097; PFAM: Protein of unknown function (DUF475) YP_004264024.1 KEGG: dra:DR_1067 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121098; TIGRFAM: gammaproteobacterial enzyme C-terminal transmembrane domain YP_004264025.1 COGs: COG0753 Catalase; InterPro IPR018028:IPR010582; KEGG: dra:DR_1998 catalase; PFAM: Catalase-related subgroup; Catalase-related immune responsive; PRIAM: Catalase; SPTR: Catalase; IMG reference gene:2504121099; PFAM: Catalase; Catalase-related immune-responsive YP_004264026.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: ddr:Deide_21450 putative metallo-beta-lactamase superfamily protein; putative Zn-dependent hydrolase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Putative Metallo-beta-lactamase superfamily protein; putative Zn-dependent Hydrolase; IMG reference gene:2504121100; PFAM: Metallo-beta-lactamase superfamily YP_004264027.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: ddr:Deide_2p00001 putative chromosome partitioning ATPase, ParA family; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Putative chromosome partitioning ATPase, ParA family; IMG reference gene:2504121101; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004264028.1 InterPro IPR003115; KEGG: dra:DR_B0030 ParB family chromosome partitioning protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: Chromosome partitioning protein, ParB family; IMG reference gene:2504121102; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004264029.1 COGs: COG5534 Plasmid replication initiator protein; InterPro IPR018777; KEGG: msv:Mesil_3348 cupin 2 conserved barrel domain protein; PFAM: Replication initiator protein A; SPTR: Cupin 2 conserved barrel domain protein; IMG reference gene:2504121103; PFAM: Replication initiator protein A YP_004264030.1 KEGG: aci:ACIAD1418 putative homocysteine S-methyltransferase family protein; SPTR: Putative homocysteine S-methyltransferase family protein; IMG reference gene:2504121104 YP_004264031.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: dge:Dgeo_0623 protein of unknown function DUF224, cysteine-rich region; PFAM: Cysteine-rich domain; 4Fe-4S binding domain; SPTR: Glycolate oxidase, Fe-S subunit; IMG reference gene:2504121105; PFAM: Cysteine-rich domain YP_004264032.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dge:Dgeo_0624 FAD linked oxidase-like protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase subunit, GlcD; IMG reference gene:2504121106; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_004264033.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094; KEGG: ddr:Deide_14041 putative glycolate oxidase subunit GlcE; PFAM: FAD linked oxidase, N-terminal; SPTR: Putative Glycolate oxidase subunit GlcE; IMG reference gene:2504121107; PFAM: FAD binding domain YP_004264034.1 KEGG: dge:Dgeo_1824 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121108; PFAM: Protein of unknown function (DUF1282) YP_004264035.1 COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: tra:Trad_0189 isochorismatase hydrolase; PFAM: Isochorismatase-like; SPTR: Isochorismatase hydrolase; IMG reference gene:2504121109; PFAM: Isochorismatase family YP_004264036.1 COGs: COG0814 Amino acid permease; InterPro IPR018227; KEGG: apa:APP7_0643 tyrosine-specific transport protein 2; PFAM: Tryptophan/tyrosine permease; SPTR: Tyrosine-specific transport protein 2; IMG reference gene:2504121110; PFAM: Tryptophan/tyrosine permease family; TIGRFAM: aromatic amino acid transport protein YP_004264037.1 KEGG: dra:DR_0569 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121111 YP_004264038.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: dge:Dgeo_2408 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein; IMG reference gene:2504121112; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family YP_004264039.1 COGs: COG2217 Cation transport ATPase; InterPro IPR006403:IPR006416:IPR001757:IPR006121:IPR008250:IPR0058 34; KEGG: msv:Mesil_0129 copper-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: ATPase, P type, cation/copper-transporter; ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504121113; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004264040.1 COGs: COG2217 Cation transport ATPase; InterPro IPR006121; KEGG: msv:Mesil_0129 copper-translocating P-type ATPase; PFAM: Heavy metal transport/detoxification protein; SPTR: Copper-translocating P-type ATPase; IMG reference gene:2504121114; PFAM: Heavy-metal-associated domain YP_004264041.1 COGs: COG2608 Copper chaperone; InterPro IPR006121; KEGG: dra:DR_2452 hypothetical protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121115; PFAM: Heavy-metal-associated domain YP_004264042.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: dra:DR_2449 hypothetical protein; PFAM: Protein of unknown function DUF156; SPTR: Putative uncharacterized protein; IMG reference gene:2504121116; PFAM: Uncharacterised BCR, COG1937 YP_004264043.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR010089:IPR008254; KEGG: dge:Dgeo_1878 flavodoxin/nitric oxide synthase; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin/nitric oxide synthase; TIGRFAM: Flavoprotein WrbA; IMG reference gene:2504121117; PFAM: NADPH-dependent FMN reductase; TIGRFAM: NAD(P)H:quinone oxidoreductase, type IV YP_004264044.1 COGs: COG0753 Catalase; InterPro IPR018028:IPR010582:IPR002818; KEGG: dra:DR_A0259 catalase; PFAM: Catalase-related subgroup; Catalase-related immune responsive; ThiJ/PfpI; PRIAM: Catalase; SPTR: Catalase; IMG reference gene:2504121118; PFAM: Catalase; DJ-1/PfpI family; Catalase-related immune-responsive YP_004264045.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856; KEGG: ddr:Deide_20321 putative tyrosine kinase; PFAM: Lipopolysaccharide biosynthesis; SPTR: Putative tyrosine kinase; IMG reference gene:2504121119; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family YP_004264046.1 InterPro IPR002797; KEGG: pam:PANA_0155 WzxE; PFAM: Polysaccharide biosynthesis protein; SPTR: WzxE; IMG reference gene:2504121120; PFAM: Polysaccharide biosynthesis protein YP_004264047.1 InterPro IPR001296; KEGG: hdn:Hden_0183 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2504121121; PFAM: Glycosyl transferases group 1 YP_004264048.1 KEGG: hdn:Hden_0184 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121122 YP_004264049.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869:IPR013692; KEGG: slp:Slip_0163 polysaccharide biosynthesis protein CapD; PFAM: Polysaccharide biosynthesis protein CapD-like; Polysaccharide biosynthesis C-terminal; PRIAM: UDP-glucose 4-epimerase; SPTR: Polysaccharide biosynthesis protein; IMG reference gene:2504121123; PFAM: Polysaccharide biosynthesis protein; Polysaccharide biosynthesis protein C-terminal YP_004264050.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sno:Snov_3210 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Capsular polysaccharide synthesis enzyme CapF; IMG reference gene:2504121124; PFAM: NAD dependent epimerase/dehydratase family YP_004264051.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: ctu:Ctu_27290 hypothetical protein; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; IMG reference gene:2504121125; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004264052.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR001296:IPR003362; KEGG: gur:Gura_1697 glycosyl transferase, group 1; PFAM: Bacterial sugar transferase; Glycosyl transferase, group 1; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Glycosyl transferase, group 1; IMG reference gene:2504121126; PFAM: Bacterial sugar transferase; Glycosyl transferases group 1 YP_004264053.1 InterPro IPR000182; KEGG: mau:Micau_2113 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504121127; PFAM: Acetyltransferase (GNAT) family YP_004264054.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: mau:Micau_2114 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; IMG reference gene:2504121128; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_004264055.1 KEGG: mau:Micau_2124 methicillin resistance protein; SPTR: Methicillin resistance protein; IMG reference gene:2504121129; PFAM: Uncharacterized conserved protein (DUF2156); FemAB family YP_004264056.1 KEGG: ddr:Deide_20252 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121130 YP_004264057.1 InterPro IPR007016; KEGG: ddr:Deide_20251 putative O-antigen polymerase; putative membrane protein; PFAM: O-antigen ligase-related; SPTR: Putative O-Antigen polymerase; putative membrane protein; IMG reference gene:2504121131; PFAM: O-Antigen ligase YP_004264058.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sat:SYN_02688 UDP-bacillosamine synthetase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: Glutamine--scyllo-inositol transaminase; SPTR: UDP-bacillosamine synthetase; IMG reference gene:2504121132; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_004264059.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003781:IPR003869; KEGG: ddr:Deide_20260 putative capsular polysaccharide biosynthesis protein CapD; putative membrane protein; PFAM: Polysaccharide biosynthesis protein CapD-like; CoA-binding; SPTR: Putative capsular polysaccharide biosynthesis protein capD; putative membrane protein; IMG reference gene:2504121133; PFAM: Polysaccharide biosynthesis protein YP_004264060.1 COGs: COG0692 Uracil DNA glycosylase; HAMAP: Uracil-DNA glycosylase; InterPro IPR002043:IPR006050:IPR005101:IPR005122; KEGG: chl:Chy400_0772 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase, FAD-binding/Cryptochrome, C-terminal; DNA photolyase, N-terminal; Uracil-DNA glycosylase-like; SPTR: Deoxyribodipyrimidine photo-lyase; TIGRFAM: Uracil-DNA glycosylase; IMG reference gene:2504121134; PFAM: FAD binding domain of DNA photolyase; Uracil DNA glycosylase superfamily; DNA photolyase; TIGRFAM: uracil-DNA glycosylase YP_004264061.1 InterPro IPR000835; KEGG: rmr:Rmar_2676 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504121135; PFAM: MarR family YP_004264062.1 KEGG: ddr:Deide_08531 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121136 YP_004264063.1 COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749; KEGG: ddr:Deide_04550 putative phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Putative phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2; IMG reference gene:2504121137; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_004264064.1 COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: dge:Dgeo_1920 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; IMG reference gene:2504121138; PFAM: FAD dependent oxidoreductase YP_004264065.1 COGs: COG2022 Uncharacterized protein of thiazole biosynthesis; HAMAP: Thiazole biosynthesis; InterPro IPR008867; KEGG: dra:DR_A0172 thiazole synthase; PFAM: Thiazole biosynthesis; SPTR: Thiazole synthase; IMG reference gene:2504121139; PFAM: Thiazole biosynthesis protein ThiG YP_004264066.1 InterPro IPR010035:IPR003749; KEGG: ddr:Deide_04525 hypothetical protein; PFAM: ThiamineS; SPTR: Putative uncharacterized protein; TIGRFAM: ThiS, thiamine-biosynthesis; IMG reference gene:2504121140; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_004264067.1 COGs: COG0352 Thiamine monophosphate synthase; HAMAP: Thiamine monophosphate synthase; InterPro IPR003733; KEGG: dra:DR_A0174 thiamin-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: Thiamine monophosphate synthase; IMG reference gene:2504121141; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004264068.1 COGs: COG0422 Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: dge:Dgeo_1924 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: Thiamine biosynthesis protein ThiC; IMG reference gene:2504121142; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC YP_004264069.1 COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IPR023019:IPR008179:IPR002496:IPR021130; KEGG: xal:XALc_1260 probable histidine biosynthesis bifunctional protein hisie (bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp pyrophosphatase protein); PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Probable histidine biosynthesis bifunctional protein hisie (Bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp pyrophosphatase protein); TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504121143; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase YP_004264070.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; HAMAP: Histidine biosynthesis, HisF; InterPro IPR004651:IPR006062; KEGG: fbl:Fbal_1707 imidazole glycerol phosphate synthase subunit HisF; PFAM: Histidine biosynthesis; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: Histidine biosynthesis, HisF; IMG reference gene:2504121144; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004264071.1 COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; InterPro IPR023016:IPR006063:IPR006062; KEGG: fbl:Fbal_1708 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; PRIAM: 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamideisomerase; SPTR: 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA; IMG reference gene:2504121145; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_004264072.1 COGs: COG0118 Glutamine amidotransferase; HAMAP: Imidazole glycerol phosphate synthase, subunit H; InterPro IPR010139:IPR000991; KEGG: asa:ASA_2105 imidazole glycerol phosphate synthase subunit HisH; PFAM: Glutamine amidotransferase class-I, C-terminal; SPTR: Imidazole glycerol phosphate synthase subunit HisH; TIGRFAM: Imidazole glycerol phosphate synthase, subunit H; IMG reference gene:2504121146; PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_004264073.1 COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; Histidine biosynthesis bifunctional protein HisB; InterPro IPR000807:IPR020566:IPR005954:IPR006543:IPR006549; KEGG: pat:Patl_2883 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Histidinol-phosphatase; SPTR: Histidine biosynthesis bifunctional protein hisB; TIGRFAM: Histidinol-phosphatase; Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; IMG reference gene:2504121147; PFAM: Imidazoleglycerol-phosphate dehydratase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; histidinol-phosphate phosphatase family domain; histidinol-phosphatase YP_004264074.1 COGs: COG0141 Histidinol dehydrogenase; HAMAP: Histidinol dehydrogenase, prokaryotic-type; InterPro IPR012131; KEGG: ilo:IL1835 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase, prokaryotic-type; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: Histidinol dehydrogenase, prokaryotic-type; IMG reference gene:2504121148; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase YP_004264075.1 COGs: COG0040 ATP phosphoribosyltransferase; HAMAP: Histidine biosynthesis HisG, ATP phosphoribosyltransferase, subgroup; InterPro IPR020621:IPR013820:IPR013115; KEGG: ilo:IL1834 ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase, catalytic domain; Histidine biosynthesis HisG, C-terminal; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, catalytic domain; Histidine biosynthesis HisG, C-terminal; IMG reference gene:2504121149; PFAM: HisG, C-terminal domain; ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, C-terminal domain; ATP phosphoribosyltransferase YP_004264076.1 COGs: COG0078 Ornithine carbamoyltransferase; HAMAP: Ornithine carbamoyltransferase; InterPro IPR002292:IPR006132:IPR006131; KEGG: psa:PST_0675 ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; PRIAM: Ornithine carbamoyltransferase; SPTR: Ornithine carbamoyltransferase 1; TIGRFAM: Ornithine carbamoyltransferase; IMG reference gene:2504121150; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_004264077.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: dra:DR_A0132 hypothetical protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121151; PFAM: GlcNAc-PI de-N-acetylase YP_004264078.1 COGs: COG1960 Acyl-CoA dehydrogenase; KEGG: dra:DR_A0134 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504121152; PFAM: Acyl-CoA dehydrogenase, C-terminal domain YP_004264079.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dge:Dgeo_1476 oxidoreductase-like protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; PRIAM: Glucose-fructose oxidoreductase; SPTR: Oxidoreductase-like protein; IMG reference gene:2504121153; PFAM: Oxidoreductase family, NAD-binding Rossmann fold YP_004264080.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: dge:Dgeo_2959 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase catalytic; IMG reference gene:2504121154; PFAM: Transglycosylase SLT domain YP_004264081.1 COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR010034:IPR003749:IPR003448; KEGG: dra:DR_2607 molybdenum cofactor biosynthesis protein D/E; PFAM: Molybdopterin biosynthesis MoaE; ThiamineS; SPTR: Molybdenum cofactor biosynthesis protein D/E; TIGRFAM: Molybdopterin converting factor, subunit 1; IMG reference gene:2504121155; PFAM: ThiS family; MoaE protein; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal YP_004264082.1 COGs: COG0385 Na+-dependent transporter; InterPro IPR002657; KEGG: ach:Achl_0445 bile acid:sodium symporter; PFAM: Bile acid:sodium symporter; SPTR: BASS family bile acid:sodium (Na+) symporter; IMG reference gene:2504121156; PFAM: Sodium Bile acid symporter family; TIGRFAM: bile acid transporter YP_004264083.1 KEGG: mbr:MONBRDRAFT_24745 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2504121158 YP_004264084.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR011299:IPR011535:IPR001127:IPR003352:IPR018113; KEGG: dge:Dgeo_2620 phosphotransferase system, glucose-specific IIBC component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; Phosphotransferase system, sugar-specific permease EIIA 1 domain; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Phosphotransferase system, glucose-specific IIBC component; TIGRFAM: Phosphotransferase system, glucose-specific IIBC component; Phosphotransferase system, glucose-like IIB component; Phosphotransferase system, sugar-specific permease EIIA 1 domain; IMG reference gene:2504121159; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component; PTS system, glucose-specific IIBC component; PTS system, glucose subfamily, IIA component YP_004264085.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: dge:Dgeo_2621 HPrNtr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphotransferase system HPr-related protein; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; IMG reference gene:2504121160; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family YP_004264086.1 COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR006318:IPR008731:IPR008279:IPR000121; KEGG: dge:Dgeo_2622 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile domain; PRIAM: Phosphoenolpyruvate--protein phosphotransferase; SPTR: Phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase; IMG reference gene:2504121161; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase YP_004264087.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: dra:DR_A0066 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase 1; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; IMG reference gene:2504121162; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_004264088.1 COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: dge:Dgeo_2624 glutamine-fructose-6-phosphate transaminase (isomerizing); PFAM: Sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glutamine-fructose-6-phosphate transaminase (Isomerizing); IMG reference gene:2504121163; PFAM: SIS domain YP_004264089.1 COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: tth:TTC1083 4-hydroxybutyrate coenzyme A transferase; PFAM: Acetyl-CoA hydrolase/transferase; SPTR: Acetyl-CoA hydrolase/transferase; IMG reference gene:2504121164; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain YP_004264090.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR006675:IPR002646:IPR006674; KEGG: tro:trd_0049 putative RNA nucleotidyltransferase; PFAM: Poly A polymerase, head domain; Metal-dependent phosphohydrolase, HD subdomain; PRIAM: tRNA cytidylyltransferase; SPTR: Possible tRNA adenylyltransferase; TIGRFAM: Uncharacterised protein family HDIG; IMG reference gene:2504121165; PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: uncharacterized domain HDIG YP_004264091.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: ddr:Deide_06270 putative ABC transporter, periplasmic component, peptide-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Putative ABC transporter, periplasmic component, peptide-binding protein; IMG reference gene:2504121166; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004264092.1 COGs: COG3546 Mn-containing catalase; InterPro IPR007760; KEGG: tra:Trad_0726 catalase; PFAM: Catalase, manganese; PRIAM: Catalase; SPTR: Catalase; IMG reference gene:2504121167; PFAM: Manganese containing catalase YP_004264093.1 InterPro IPR006626:IPR022441:IPR013247; KEGG: dra:DR_A0335 serine/threonine protein kinase, putative; PFAM: SH3, type 3; SPTR: Putative kinase; TIGRFAM: Parallel beta-helix repeat-2; IMG reference gene:2504121168; PFAM: Bacterial SH3 domain; TIGRFAM: parallel beta-helix repeat (two copies) YP_004264094.1 KEGG: dra:DR_A0182 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121169 YP_004264095.1 COGs: COG0159 Tryptophan synthase alpha chain; HAMAP: Tryptophan synthase, alpha chain; InterPro IPR002028; KEGG: sfr:Sfri_1424 tryptophan synthase subunit alpha; PFAM: Tryptophan synthase, alpha chain; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase alpha chain; TIGRFAM: Tryptophan synthase, alpha chain; IMG reference gene:2504121170; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit YP_004264096.1 COGs: COG0133 Tryptophan synthase beta chain; HAMAP: Tryptophan synthase beta chain/beta chain-like; InterPro IPR023026:IPR006654:IPR001926; KEGG: ilo:IL1755 tryptophan synthase subunit beta; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain; TIGRFAM: Tryptophan synthase, beta chain; IMG reference gene:2504121171; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit YP_004264097.1 COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001240; KEGG: cef:CE2871 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Indole-3-glycerol-phosphate synthase., Phosphoribosylanthranilate isomerase; SPTR: Tryptophan biosynthesis protein trpCF; IMG reference gene:2504121172; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase YP_004264098.1 COGs: COG0547 Anthranilate phosphoribosyltransferase; HAMAP: Anthranilate phosphoribosyl transferase; InterPro IPR005940:IPR017459:IPR000312; KEGG: aap:NT05HA_0810 anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase, family 3; Glycosyl transferase, family 3, N-terminal; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: Anthranilate phosphoribosyl transferase; IMG reference gene:2504121173; PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_004264099.1 COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991; KEGG: car:cauri_2508 anthranilate synthase component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component II; IMG reference gene:2504121174; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004264100.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR005257:IPR006805:IPR015890; KEGG: fbl:Fbal_2536 anthranilate synthase, component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase, component I; TIGRFAM: Anthranilate synthase component I, TrpE-like, bacterial; IMG reference gene:2504121175; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: anthranilate synthase component I, proteobacterial subset YP_004264101.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ddr:Deide_13330 putative 5 -nucleotidases (UshA), precursor; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative 5-nucleotidases (UshA),; IMG reference gene:2504121176; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain YP_004264102.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099; KEGG: ddr:Deide_09830 putative coenzyme A disulfide reductase (CoA-disulfide reductase) (CoADR); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SPTR: Putative Coenzyme A disulfide reductase (CoA-disulfide reductase) (CoADR); IMG reference gene:2504121177; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004264103.1 KEGG: sna:Snas_3533 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121178 YP_004264104.1 KEGG: dge:Dgeo_0893 hypothetical protein; SPTR: Winged HTH DNA-binding domain; IMG reference gene:2504121179; PFAM: FeoC like transcriptional regulator YP_004264105.1 COGs: COG0370 Fe2+ transport system protein B; InterPro IPR005225:IPR003373:IPR002917:IPR011619:IPR011642:IPR0116 40; KEGG: dra:DR_1219 ferrous iron transport protein B; PFAM: Ferrous iron transport protein B, N-terminal; GTP-binding protein, HSR1-related; Nucleoside recognition; Ferrous iron transport protein B, C-terminal; SPTR: Ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein; IMG reference gene:2504121180; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB YP_004264106.1 COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: dra:DR_1220 ferrous iron transport protein A; PFAM: Ferrous iron transporter, FeoA subunit; SMART: Ferrous iron transporter, FeoA subunit; SPTR: Ferrous iron transport protein A; IMG reference gene:2504121181; PFAM: FeoA domain YP_004264107.1 COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: bpf:BpOF4_02235 carbon starvation protein CstA; PFAM: Carbon starvation protein CstA; SPTR: Carbon starvation protein CstA; IMG reference gene:2504121182; PFAM: Carbon starvation protein CstA YP_004264108.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: ddr:Deide_3p01240 putative transcriptional regulator, LysR family; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Putative transcriptional regulator, LysR family; IMG reference gene:2504121183; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004264109.1 InterPro IPR000835; KEGG: dra:DR_A0248 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504121184 YP_004264110.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dra:DR_A0247 drug transport protein, putative; PFAM: Major facilitator superfamily MFS-1; SPTR: Drug transport protein, putative; IMG reference gene:2504121185; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_004264111.1 COGs: COG2986 Histidine ammonia-lyase; HAMAP: Histidine ammonia-lyase; InterPro IPR005921:IPR001106; KEGG: dra:DR_A0147 histidine ammonia-lyase; PFAM: Phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: Histidine ammonia-lyase; IMG reference gene:2504121186; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase YP_004264112.1 COGs: COG1228 Imidazolonepropionase and related amidohydrolase; HAMAP: Imidazolonepropionase; InterPro IPR005920:IPR006680; KEGG: dra:DR_A0148 imidazolonepropionase; PFAM: Amidohydrolase 1; PRIAM: Imidazolonepropionase; SPTR: Imidazolonepropionase; TIGRFAM: Imidazolonepropionase; IMG reference gene:2504121187; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase YP_004264113.1 COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035; KEGG: dra:DR_A0149 agmatinase, putative; PFAM: Ureohydrolase; PRIAM: Agmatinase; SPTR: Agmatinase, putative; IMG reference gene:2504121188; PFAM: Arginase family; TIGRFAM: agmatinase YP_004264114.1 KEGG: gym:GYMC10_4328 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121189; PFAM: Protein of unknown function (DUF664) YP_004264115.1 COGs: COG2987 Urocanate hydratase; HAMAP: Urocanase; InterPro IPR000193; KEGG: dra:DR_A0151 urocanate hydratase; PFAM: Urocanase; PRIAM: Urocanate hydratase; SPTR: Urocanate hydratase; TIGRFAM: Urocanase; IMG reference gene:2504121190; PFAM: Urocanase; TIGRFAM: urocanate hydratase YP_004264116.1 COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: dge:Dgeo_2736 IclR family transcriptional regulator; PFAM: Transcription regulator IclR, N-terminal; Transcription regulator IclR, C-terminal; SMART: Transcription regulator IclR, N-terminal; SPTR: Transcriptional regulator, IclR family; IMG reference gene:2504121191; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004264117.1 InterPro IPR014867; KEGG: mxa:MXAN_5581 putative lipoprotein; PFAM: Spore coat protein CotH; SPTR: Putative lipoprotein; IMG reference gene:2504121192; PFAM: CotH protein YP_004264118.1 KEGG: dra:DR_A0230 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121193; PFAM: Domain of unknown function (DUF1990) YP_004264119.1 InterPro IPR018960; KEGG: dra:DR_A0229 hypothetical protein; PFAM: Domain of unknown function DUF1990; SPTR: Putative uncharacterized protein; IMG reference gene:2504121194; PFAM: Domain of unknown function (DUF1990) YP_004264120.1 COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR004572:IPR002937; KEGG: dra:DR_1130 protoporphyrinogen oxidase; PFAM: Amine oxidase; PRIAM: Protoporphyrinogen oxidase; SPTR: Protoporphyrinogen oxidase; TIGRFAM: Protoporphyrinogen oxidase; IMG reference gene:2504121195; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: protoporphyrinogen oxidase YP_004264121.1 COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); HAMAP: Ferrochelatase; InterPro IPR001015; KEGG: dra:DR_1131 ferrochelatase; PFAM: Ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: Ferrochelatase; IMG reference gene:2504121196; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase YP_004264122.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; HAMAP: Uroporphyrinogen decarboxylase HemE; InterPro IPR006361:IPR000257; KEGG: dra:DR_1133 uroporphyrinogen decarboxylase; PFAM: Uroporphyrinogen decarboxylase (URO-D); PRIAM: Uroporphyrinogen decarboxylase; SPTR: Uroporphyrinogen decarboxylase; TIGRFAM: Uroporphyrinogen decarboxylase HemE; IMG reference gene:2504121197; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: uroporphyrinogen decarboxylase YP_004264123.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: dra:DR_A0153 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121198; PFAM: SNARE associated Golgi protein YP_004264124.1 COGs: COG1162 GTPase; HAMAP: Ribosome biogenesis GTPase RsgA, putative; InterPro IPR004881; KEGG: ddr:Deide_03610 putative GTPase EngC protein 2; PFAM: Ribosome biogenesis GTPase RsgA, putative; SPTR: Putative ribosome biogenesis GTPase RsgA; IMG reference gene:2504121199; PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A YP_004264125.1 KEGG: dra:DR_2182 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121200 YP_004264126.1 COGs: COG2229 GTPase; InterPro IPR005225:IPR004130; KEGG: dra:DR_2181 hypothetical protein; PFAM: Uncharacterised protein family, ATP binding; SPTR: Putative uncharacterized protein; TIGRFAM: Small GTP-binding protein; IMG reference gene:2504121201; PFAM: Conserved hypothetical ATP binding protein; TIGRFAM: small GTP-binding protein domain YP_004264127.1 COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: dra:DR_2180 hypothetical protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504121202; PFAM: Roadblock/LC7 domain YP_004264128.1 COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR012690:IPR002529; KEGG: dge:Dgeo_2420 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetase, C-terminal-like; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; IMG reference gene:2504121203; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_004264129.1 InterPro IPR004360; KEGG: dra:DR_A0228 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121204 YP_004264130.1 COGs: COG3836 2 4-dihydroxyhept-2-ene-1 7-dioic acid aldolase; InterPro IPR005000; KEGG: ddr:Deide_2p00030 putative 2-dehydro-3-deoxyglucarate aldolase; PFAM: Aldehyde-lyase domain; PRIAM: 4-hydroxy-2-oxovalerate aldolase; SPTR: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; IMG reference gene:2504121205; PFAM: HpcH/HpaI aldolase/citrate lyase family; TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_004264131.1 COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: dra:DR_B0106 hypothetical protein; PFAM: Thioesterase superfamily; SPTR: Putative uncharacterized protein; IMG reference gene:2504121206; PFAM: Thioesterase superfamily YP_004264132.1 COGs: COG3424 naringenin-chalcone synthase; InterPro IPR001099:IPR012328; KEGG: dra:DR_A0326 chalcone synthase, putative; PFAM: Chalcone/stilbene synthase, C-terminal; Chalcone/stilbene synthase, N-terminal; PRIAM: Naringenin-chalcone synthase; SPTR: Chalcone synthase, putative; IMG reference gene:2504121207; PFAM: Chalcone and stilbene synthases, N-terminal domain; Chalcone and stilbene synthases, C-terminal domain YP_004264133.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: dra:DR_A0327 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; IMG reference gene:2504121208; PFAM: Methyltransferase domain YP_004264134.1 COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR002938; KEGG: dra:DR_A0328 oxidoreductase, putative; PFAM: Monooxygenase, FAD-binding; SPTR: Oxidoreductase, putative; IMG reference gene:2504121209; PFAM: FAD binding domain YP_004264135.1 COGs: COG2759 Formyltetrahydrofolate synthetase; HAMAP: Formate-tetrahydrofolate ligase, FTHFS; InterPro IPR000559; KEGG: pak:HMPREF0675_3049 formate--tetrahydrofolate ligase; PFAM: Formate-tetrahydrofolate ligase, FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; IMG reference gene:2504121210; PFAM: Formate--tetrahydrofolate ligase YP_004264136.1 COGs: COG3633 Na+/serine symporter; HAMAP: Serine/threonine transporter SstT; InterPro IPR023025:IPR001991; KEGG: pcr:Pcryo_0049 serine/threonine transporter SstT; PFAM: Sodium:dicarboxylate symporter; SPTR: Serine/threonine transporter sstT; IMG reference gene:2504121211; PFAM: Sodium:dicarboxylate symporter family YP_004264137.1 COGs: COG1975 Xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR003777; KEGG: dra:DR_A0129 hypothetical protein; PFAM: XdhC- CoxI; SPTR: Putative uncharacterized protein; IMG reference gene:2504121212; PFAM: XdhC and CoxI family YP_004264138.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR020843:IPR013154:IPR013149; KEGG: dge:Dgeo_0753 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: Alcohol dehydrogenase, zinc-binding; IMG reference gene:2504121213; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004264139.1 COGs: COG2068 Uncharacterized MobA-related protein; KEGG: dra:DR_A0004 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121214 YP_004264140.1 COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: dra:DR_A0231 oxidoreductase; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; PRIAM: Xanthine dehydrogenase; SPTR: Oxidoreductase; IMG reference gene:2504121215; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain YP_004264141.1 COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346; KEGG: aav:Aave_1486 molybdopterin dehydrogenase, FAD-binding; PFAM: Molybdopterin dehydrogenase, FAD-binding; PRIAM: Xanthine dehydrogenase; SPTR: Molybdopterin dehydrogenase, FAD-binding protein; IMG reference gene:2504121216; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain YP_004264142.1 COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: dra:DR_A0233 oxidoreductase, iron-sulfur subunit; PFAM: [2Fe-2S]-binding; Ferredoxin; SPTR: Oxidoreductase, iron-sulfur subunit; IMG reference gene:2504121217; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain YP_004264143.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR001041:IPR019574:IPR001450:IPR006963:IPR006656:IPR0066 57:IPR006478; KEGG: dge:Dgeo_2746 formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; PRIAM: Nitrate reductase; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: Formate dehydrogenase, alpha subunit; IMG reference gene:2504121218; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type YP_004264144.1 InterPro IPR012440; KEGG: ddr:Deide_2p01510 hypothetical protein; PFAM: Protein of unknown function DUF1641; SPTR: Putative uncharacterized protein; IMG reference gene:2504121219; PFAM: Protein of unknown function (DUF1641) YP_004264145.1 COGs: COG1526 Uncharacterized protein required for formate dehydrogenase activity; InterPro IPR003786; KEGG: dge:Dgeo_2744 formate dehydrogenase family accessory protein FdhD; PFAM: Formate dehydrogenase, subunit FdhD; SPTR: Formate dehydrogenase family accessory protein FdhD; IMG reference gene:2504121220; PFAM: FdhD/NarQ family; TIGRFAM: formate dehydrogenase family accessory protein FdhD YP_004264146.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209; KEGG: dra:DR_A0064 serine protease; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; SPTR: Serine protease, subtilase family; IMG reference gene:2504121221; PFAM: Subtilase family YP_004264147.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dra:DR_A0065 DNA-binding protein HB; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: DNA-binding protein HU; IMG reference gene:2504121222; PFAM: Bacterial DNA-binding protein YP_004264148.1 KEGG: dge:Dgeo_1591 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121223 YP_004264149.1 InterPro IPR001845; KEGG: kfl:Kfla_1894 transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family; IMG reference gene:2504121224; PFAM: Bacterial regulatory protein, arsR family YP_004264150.1 COGs: COG2217 Cation transport ATPase; InterPro IPR008250:IPR005834:IPR006404:IPR006416:IPR001757; KEGG: dra:DR_A0073 cation-transporting P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Cation-transporting P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504121225; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004264151.1 InterPro IPR001506:IPR006026; KEGG: ddr:Deide_09170 putative extracellular serine proteinase; PFAM: Peptidase M12A, astacin; SMART: Peptidase, metallopeptidase; SPTR: Putative extracellular serine proteinase; IMG reference gene:2504121226; PFAM: Astacin (Peptidase family M12A) YP_004264152.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: dge:Dgeo_2423 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Stomatin/prohibitin family protein; IMG reference gene:2504121227; PFAM: SPFH domain / Band 7 family YP_004264153.1 KEGG: dmo:Dmoj_GI17320 GI17320 gene product from transcript GI17320-RA; SPTR: CG8965; manually curated; IMG reference gene:2504121228 YP_004264154.1 COGs: COG3415 Transposase and inactivated derivatives; KEGG: dra:DR_2425 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504121230; PFAM: Transposase YP_004264155.1 InterPro IPR002559; KEGG: dge:Dgeo_2989 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein; IMG reference gene:2504121231; PFAM: Transposase DDE domain YP_004264156.1 KEGG: dmo:Dmoj_GI17320 GI17320 gene product from transcript GI17320-RA; SPTR: CG8965; IMG reference gene:2504121232 YP_004264157.1 InterPro IPR002559; KEGG: dra:DR_C0033 transposase, putative; PFAM: Transposase, IS4-like; SPTR: Transposase, putative; IMG reference gene:2504121233; PFAM: Transposase DDE domain YP_004264158.1 COGs: COG2076 Membrane transporter of cations and cationic drugs; InterPro IPR000390; KEGG: dra:DR_1005 SugE protein; PFAM: Small multidrug resistance protein; SPTR: SugE protein; IMG reference gene:2504121234; PFAM: Small Multidrug Resistance protein YP_004264159.1 COGs: COG2076 Membrane transporter of cations and cationic drugs; InterPro IPR000390; KEGG: dra:DR_1004 SugE protein; PFAM: Small multidrug resistance protein; SPTR: SugE protein; IMG reference gene:2504121235; PFAM: Small Multidrug Resistance protein YP_004264160.1 KEGG: dra:DR_1003 transcriptional regulator; SPTR: Transcriptional regulator; IMG reference gene:2504121236; PFAM: Bacterial regulatory proteins, tetR family YP_004264161.1 KEGG: cak:Caul_1919 major facilitator transporter; SPTR: Inner membrane protein translocase; IMG reference gene:2504121237 YP_004264162.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; HAMAP: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase; InterPro IPR000713:IPR013221:IPR004101:IPR005761; KEGG: dra:DR_0297 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6- diaminopimelate ligase; SPTR: UDP-N-acetylmuramyl-tripeptide synthetase; TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase; IMG reference gene:2504121238; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase YP_004264163.1 COGs: COG2388 acetyltransferase; KEGG: psa:PST_4142 acetyltransferase; SPTR: Predicted acetyltransferase; IMG reference gene:2504121239 YP_004264164.1 COGs: COG2366 Protein related to penicillin acylase; InterPro IPR002692; KEGG: dge:Dgeo_0269 penicillin amidase; PFAM: Peptidase S45, penicillin amidase; SPTR: Penicillin amidase; IMG reference gene:2504121240; PFAM: Penicillin amidase YP_004264165.1 KEGG: kla:KLLA0E14543g hypothetical protein; SPTR: KLLA0E14543p; IMG reference gene:2504121241 YP_004264166.1 COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375:IPR015376:IPR000086; KEGG: dra:DR_1168 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal; PRIAM: NAD(+) diphosphatase; SPTR: NADH pyrophosphatase; IMG reference gene:2504121242; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain YP_004264167.1 InterPro IPR002559; KEGG: dra:DR_C0033 transposase, putative; PFAM: Transposase, IS4-like; SPTR: Transposase, putative; IMG reference gene:2504121243; PFAM: Transposase DDE domain YP_004264168.1 COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001440:IPR000160:IPR001633:IPR019734; KEGG: ddr:Deide_21850 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide TPR-1; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504121244; PFAM: EAL domain; GGDEF domain; Tetratricopeptide repeat; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004264169.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dra:DR_1327 multidrug-efflux transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Multidrug-efflux transporter; IMG reference gene:2504121245; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; Multidrug resistance protein YP_004264170.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterPro IPR006674:IPR003607; KEGG: ava:Ava_1993 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504121246; PFAM: HD domain YP_004264171.1 COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR003439:IPR004602; KEGG: dra:DR_A0188 excinuclease ABC, subunit A; PFAM: ABC transporter-like; SPTR: Excinuclease ABC, subunit A; TIGRFAM: Excinuclease ABC, A subunit; IMG reference gene:2504121247; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004264172.1 COGs: COG3685 conserved hypothetical protein; InterPro IPR010287; KEGG: dge:Dgeo_2297 hypothetical protein; PFAM: Protein of unknown function DUF892; SPTR: Putative uncharacterized protein; IMG reference gene:2504121248; PFAM: Domain of unknown function (DUF892) YP_004264173.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151; KEGG: mrb:Mrub_1209 peptidase S41; PFAM: Peptidase S41; PDZ/DHR/GLGF; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: Peptidase S41; IMG reference gene:2504121249; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004264174.1 KEGG: mrb:Mrub_1208 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121250 YP_004264175.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: scl:sce9140 putative oxidoreductase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein; IMG reference gene:2504121251; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain YP_004264176.1 COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR004680; KEGG: avn:Avin_13910 integral membrane permease/GntP family/citrate transporter; PFAM: Divalent ion symporter; SPTR: Gluconate permease; IMG reference gene:2504121252; PFAM: Citrate transporter YP_004264177.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: ddr:Deide_14910 putative 3-hydroxybutyrate dehydrogenase; short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-hydroxybutyrate dehydrogenase; SPTR: Putative 3-hydroxybutyrate dehydrogenase; short chain dehydrogenase; IMG reference gene:2504121253; PFAM: short chain dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase YP_004264178.1 COGs: COG2354 conserved hypothetical protein; InterPro IPR008526; KEGG: ddr:Deide_09970 hypothetical protein; PFAM: Protein of unknown function DUF808; SPTR: Putative uncharacterized protein; IMG reference gene:2504121254; PFAM: Protein of unknown function (DUF808) YP_004264179.1 KEGG: dra:DR_B0110 thioredoxin-related protein; SPTR: Thioredoxin-related protein; IMG reference gene:2504121255 YP_004264180.1 COGs: COG0208 Ribonucleotide reductase beta subunit; InterPro IPR000358; KEGG: dra:DR_B0109 ribonucleotide-diphosphate reductase subunit beta; PFAM: Ribonucleotide reductase; PRIAM: Ribonucleoside-diphosphate reductase; SPTR: Ribonucleoside-diphosphate reductase, beta chain; IMG reference gene:2504121256; PFAM: Ribonucleotide reductase, small chain YP_004264181.1 InterPro IPR013554:IPR013509:IPR000788:IPR013346; KEGG: dra:DR_B0108 ribonucleoside-diphosphate reductase, alpha chain; PFAM: Ribonucleotide reductase large subunit, C-terminal; Ribonucleotide reductase N-terminal; Ribonucleotide reductase large subunit, N-terminal; SPTR: Ribonucleoside-diphosphate reductase; TIGRFAM: Ribonucleoside-diphosphate reductase, alpha subunit; IMG reference gene:2504121257; PFAM: Ribonucleotide reductase N-terminal; Ribonucleotide reductase, all-alpha domain; Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit YP_004264182.1 COGs: COG1780 Protein involved in ribonucleotide reduction; InterPro IPR004465; KEGG: dra:DR_B0107 ribonucleotide reductase; PFAM: Ribonucleotide reductase Class Ib, NrdI; SPTR: Protein nrdI; TIGRFAM: Ribonucleotide reductase Class Ib, NrdI; IMG reference gene:2504121258; PFAM: NrdI Flavodoxin like; TIGRFAM: ribonucleoside-diphosphate reductase 2, operon protein nrdI YP_004264183.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: dra:DR_A0155 integrase/recombinase, putative; PFAM: Integrase, catalytic core, phage; SPTR: Integrase/recombinase, putative; IMG reference gene:2504121259; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family YP_004264184.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR013656:IPR000005:IPR000014:IPR018060; KEGG: ddr:Deide_3p02000 putative transcriptional regulator, AraC family; PFAM: PAS fold-4; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; SPTR: Putative transcriptional regulator, AraC family; TIGRFAM: PAS; IMG reference gene:2504121260; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; PAS fold; TIGRFAM: PAS domain S-box YP_004264185.1 InterPro IPR000620; KEGG: ddr:Deide_3p02010 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504121261; PFAM: EamA-like transporter family YP_004264186.1 COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR004754:IPR022461; KEGG: psa:PST_3977 arginine/ornithine antiporter; PFAM: Amino acid permease domain; SPTR: Arginine/ornithine antiporter; TIGRFAM: Arginine/ornithine antiporter; Amino acid antiporter; IMG reference gene:2504121262; PFAM: Amino acid permease; TIGRFAM: arginine/ornithine antiporter; transporter, basic amino acid/polyamine antiporter (APA) family YP_004264187.1 COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: mms:mma_3561 isochorismatase hydrolase; PFAM: Isochorismatase-like; SPTR: Isochorismatase hydrolase; IMG reference gene:2504121264; PFAM: Isochorismatase family YP_004264188.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: dra:DR_2248 dipeptidyl peptidase IV-related protein; SPTR: Dipeptidyl peptidase IV-related protein; IMG reference gene:2504121265; PFAM: Prolyl oligopeptidase family YP_004264189.1 KEGG: dra:DR_A0140 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121266 YP_004264190.1 InterPro IPR001087; KEGG: rmr:Rmar_0133 hypothetical protein; PFAM: Lipase, GDSL; SPTR: Putative uncharacterized protein; IMG reference gene:2504121267; PFAM: GDSL-like Lipase/Acylhydrolase YP_004264191.1 COGs: COG1811 Uncharacterized membrane protein possible Na+ channel or pump; InterPro IPR007563; KEGG: dge:Dgeo_1312 hypothetical protein; PFAM: Protein of unknown function DUF554; SPTR: Putative uncharacterized protein; IMG reference gene:2504121268; PFAM: Protein of unknown function (DUF554) YP_004264192.1 COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: dge:Dgeo_1770 beta-lactamase; PFAM: Beta-lactamase-related; SPTR: Beta-lactamase; IMG reference gene:2504121269; PFAM: Beta-lactamase YP_004264193.1 COGs: COG1511 membrane protein; InterPro IPR017500:IPR017501; KEGG: dge:Dgeo_2467 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Phage infection protein, YhgE, C-terminal; Phage infection protein, YhgE, N-terminal; IMG reference gene:2504121270; TIGRFAM: X-X-X-Leu-X-X-Gly heptad repeats; YhgE/Pip C-terminal domain; YhgE/Pip N-terminal domain YP_004264194.1 InterPro IPR001647; KEGG: dra:DR_0074 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504121271; PFAM: Bacterial regulatory proteins, tetR family YP_004264195.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: dra:DR_0551 glutaryl-CoA dehydrogenase, putative; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; PRIAM: Glutaryl-CoA dehydrogenase; SPTR: Glutaryl-CoA dehydrogenase, putative; IMG reference gene:2504121272; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004264196.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334; KEGG: sde:Sde_0580 alkaline phosphatase; PFAM: 5'-Nucleotidase, C-terminal; PRIAM: 5'-nucleotidase; SPTR: 5'-Nucleotidase-like protein; IMG reference gene:2504121273; PFAM: 5'-nucleotidase, C-terminal domain YP_004264197.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR011620:IPR000160; KEGG: dra:DR_1090 GGDEF family protein; PFAM: Diguanylate cyclase, predicted; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF family protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504121274; PFAM: 5TMR of 5TMR-LYT; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004264198.1 COGs: COG2031 Short chain fatty acids transporter; InterPro IPR006160; KEGG: pcr:Pcryo_0888 short chain fatty acid transporter; PFAM: Short chain fatty acid transporter; SPTR: Short-chain fatty acids transporter; IMG reference gene:2504121275; PFAM: Short chain fatty acid transporter; TIGRFAM: TIGR00366 family protein YP_004264199.1 COGs: COG0014 Gamma-glutamyl phosphate reductase; HAMAP: Glutamate-5-semialdehyde dehydrogenase; InterPro IPR000965:IPR012134; KEGG: dsh:Dshi_1469 gamma-glutamyl phosphate reductase; PRIAM: Glutamate-5-semialdehyde dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: Gamma-glutamyl phosphate reductase GPR; IMG reference gene:2504121277; PFAM: Aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase YP_004264200.1 COGs: COG0263 Glutamate 5-kinase; HAMAP: Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase; InterPro IPR001048:IPR002478:IPR005715; KEGG: pde:Pden_4055 gamma-glutamyl kinase; PFAM: Aspartate/glutamate/uridylate kinase; Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: Glutamate 5-kinase; TIGRFAM: Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase; IMG reference gene:2504121278; PFAM: PUA domain; Amino acid kinase family; TIGRFAM: glutamate 5-kinase YP_004264201.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: tra:Trad_2228 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Aldehyde Dehydrogenase; IMG reference gene:2504121279; PFAM: Aldehyde dehydrogenase family YP_004264202.1 KEGG: msv:Mesil_2916 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121280 YP_004264203.1 COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: tra:Trad_0060 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; IMG reference gene:2504121281; PFAM: FAD dependent oxidoreductase YP_004264204.1 COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterPro IPR003018:IPR003661:IPR003594; KEGG: ddr:Deide_3p02350 putative histidine kinase, classic; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Putative histidine kinase, classic; IMG reference gene:2504121282; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain YP_004264205.1 COGs: COG2823 periplasmic or secreted lipoprotein; InterPro IPR007055:IPR014004; KEGG: dge:Dgeo_0141 transport-associated; PFAM: Transport-associated; SMART: Transport-associated and nodulation domain, bacteria; SPTR: Signaling BON domain protein, osmotic stress response related; IMG reference gene:2504121283; PFAM: Putative phospholipid-binding domain YP_004264206.1 COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198:IPR020842; KEGG: lby:Lbys_0212 short-chain dehydrogenase/reductase sdr; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Oxidoreductase, short-chain dehydrogenase/reductase family; IMG reference gene:2504121284; PFAM: short chain dehydrogenase YP_004264207.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: dge:Dgeo_2172 DeoR family transcriptional regulator; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504121285; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004264208.1 COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR002178:IPR005698:IPR008731:IPR008279:IPR000121:IPR0063 18; KEGG: ddr:Deide_20750 putative phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; Phosphotransferase system, phosphocarrier HPr protein; Phosphotransferase system, PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile domain; SPTR: Putative phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase; IMG reference gene:2504121286; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PTS HPr component phosphorylation site; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PEP-utilising enzyme, N-terminal; TIGRFAM: Phosphotransferase System HPr (HPr) Family; phosphoenolpyruvate-protein phosphotransferase YP_004264209.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR017583:IPR022463; KEGG: dra:DR_B0074 1-phosphofructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: 1-phosphofructokinase; SPTR: 1-phosphofructokinase; TIGRFAM: Tagatose/fructose phosphokinase; 1-phosphofructokinase; IMG reference gene:2504121287; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family YP_004264210.1 COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterPro IPR003352:IPR003353:IPR006327; KEGG: ddr:Deide_20770 putative fructose IIC component, phosphotransferase system; putative membrane protein; PFAM: Phosphotransferase system, EIIC; SPTR: Putative fructose IIC component, phosphotransferase system; putative membrane protein; TIGRFAM: Phosphotransferase system, fructose IIC component; Phosphotransferase system, fructose-specific IIB subunit; IMG reference gene:2504121288; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component YP_004264211.1 KEGG: cre:CHLREDRAFT_142312 hypothetical protein; SPTR: Ferredoxin reductase; IMG reference gene:2504121289 YP_004264212.1 InterPro IPR013216; KEGG: dra:DR_A0130 methyltransferase, putative; PFAM: Methyltransferase type 11; SPTR: Methyltransferase, putative; IMG reference gene:2504121290; PFAM: Nodulation protein S (NodS) YP_004264213.1 InterPro IPR001173; KEGG: dra:DR_A0287 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: Putative uncharacterized protein; IMG reference gene:2504121291; PFAM: Glycosyl transferase family 2 YP_004264214.1 InterPro IPR001296; KEGG: dra:DR_A0368 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Putative uncharacterized protein; IMG reference gene:2504121292 YP_004264215.1 COGs: COG0562 UDP-galactopyranose mutase; InterPro IPR006076:IPR015899:IPR004379; KEGG: dra:DR_A0367 UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase, C-terminal; FAD dependent oxidoreductase; PRIAM: UDP-galactopyranose mutase; SPTR: UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; IMG reference gene:2504121293; PFAM: UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase YP_004264216.1 COGs: COG3844 Kynureninase; InterPro IPR000192:IPR010111; KEGG: dge:Dgeo_1534 kynureninase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Kynureninase; SPTR: Kynureninase; TIGRFAM: Kynureninase; manually curated; IMG reference gene:2504121295; PFAM: Aminotransferase class-V; TIGRFAM: kynureninase YP_004264217.1 KEGG: dra:DR_2593 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121296 YP_004264218.1 COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: ddr:Deide_15520 putative cyclase; putative predicted metal-dependent hydrolase; PFAM: Putative cyclase; PRIAM: Arylformamidase; SPTR: Putative cyclase; putative Predicted metal-dependent hydrolase; IMG reference gene:2504121297; PFAM: Putative cyclase; TIGRFAM: arylformamidase YP_004264219.1 KEGG: dra:DR_0509 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121298 YP_004264220.1 KEGG: afv:AFLA_007560 F5/8 type C domain protein; SPTR: Predicted protein; IMG reference gene:2504121299; PFAM: GlcNAc-PI de-N-acetylase YP_004264221.1 COGs: COG3483 Tryptophan 2 3-dioxygenase (vermilion); InterPro IPR004981:IPR017485; KEGG: dra:DR_A0339 tryptophan 2,3-dioxygenase, putative; PFAM: Tryptophan 2,3-dioxygenase; SPTR: Tryptophan 2,3-dioxygenase, putative; TIGRFAM: Tryptophan 2,3-dioxygenase, bacteria; IMG reference gene:2504121300; PFAM: Tryptophan 2,3-dioxygenase; TIGRFAM: tryptophan 2,3-dioxygenase YP_004264222.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: dra:DR_A0005 alcohol dehydrogenase, zinc-containing; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; PRIAM: S-(hydroxymethyl)glutathione dehydrogenase; SPTR: Alcohol dehydrogenase, zinc-containing; IMG reference gene:2504121301; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004264223.1 COGs: COG5637 integral membrane protein; InterPro IPR005031; KEGG: dra:DR_A0006 hypothetical protein; PFAM: Streptomyces cyclase/dehydrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504121302; PFAM: Polyketide cyclase / dehydrase and lipid transport YP_004264224.1 COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: bpf:BpOF4_04990 hypothetical protein; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504121303; PFAM: Na+/H+ antiporter family YP_004264225.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR010259:IPR000209; KEGG: dge:Dgeo_0978 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Proteinase inhibitor I9, subtilisin propeptide; PRIAM: Aqualysin 1; SPTR: Peptidase S8 and S53, subtilisin, kexin, sedolisin; IMG reference gene:2504121304; PFAM: Peptidase inhibitor I9; Subtilase family YP_004264226.1 COGs: COG1231 Monoamine oxidase; InterPro IPR002937:IPR006311; KEGG: dge:Dgeo_1827 twin-arginine translocation pathway signal; PFAM: Amine oxidase; PRIAM: L-amino-acid oxidase; SPTR: Flavin-containing amine oxidase; IMG reference gene:2504121305; PFAM: Flavin containing amine oxidoreductase YP_004264227.1 InterPro IPR003088; KEGG: dra:DR_A0275 cytochrome c6, putative; PFAM: Cytochrome c, class I; SPTR: Cytochrome C6, putative; IMG reference gene:2504121306; PFAM: Cytochrome c YP_004264228.1 COGs: COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); HAMAP: Holo-[acyl carrier protein] synthase; InterPro IPR008278:IPR004568:IPR002582; KEGG: dge:Dgeo_1927 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-[acyl-carrier-protein] synthase; TIGRFAM: Phosphopantethiene-protein transferase; IMG reference gene:2504121307; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase YP_004264229.1 COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005858:IPR005856; KEGG: sli:Slin_5857 cysteine synthase B; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase B; IMG reference gene:2504121308; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteine synthase B YP_004264230.1 COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; IMG reference gene:2504121309; TIGRFAM: serine O-acetyltransferase YP_004264231.1 COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: dra:DR_1905 GntR family transcriptional regulator; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; GntR, C-terminal; SPTR: Transcriptional regulator, GntR family; IMG reference gene:2504121310; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004264232.1 COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: dra:DR_1906 L-lactate permease, putative; PFAM: L-lactate permease; SPTR: L-lactate permease, putative; TIGRFAM: L-lactate permease; IMG reference gene:2504121311; PFAM: L-lactate permease; TIGRFAM: L-lactate transport YP_004264233.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: dra:DR_1907 fumarate reductase-related protein; PFAM: Cysteine-rich domain; SPTR: Fumarate reductase-related protein; IMG reference gene:2504121312; PFAM: Cysteine-rich domain YP_004264234.1 COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741; KEGG: ddr:Deide_3p01580 hypothetical protein; PFAM: Domain of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504121313; PFAM: Domain of unknown function (DUF3390); Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein YP_004264235.1 COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: dra:DR_1909 hypothetical protein; PFAM: Domain of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504121314; PFAM: Uncharacterised ACR, YkgG family COG1556 YP_004264236.1 InterPro IPR011701; KEGG: ddr:Deide_02630 putative major facilitator superfamily MFS_1 transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative Major facilitator superfamily MFS_1 transporter; IMG reference gene:2504121315; PFAM: Major Facilitator Superfamily YP_004264237.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: dra:DR_0096 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein, MsbA family; IMG reference gene:2504121316; PFAM: ABC transporter transmembrane region; ABC transporter YP_004264238.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: dra:DR_0095 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504121317; PFAM: ABC transporter transmembrane region; ABC transporter YP_004264239.1 COGs: COG5640 Secreted trypsin-like serine protease; InterPro IPR001254; KEGG: ddr:Deide_09160 putative trypsin-like serine protease, precursor; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PRIAM: Trypsin., Aqualysin 1; SMART: Peptidase S1/S6, chymotrypsin/Hap; SPTR: Putative Trypsin-like serine protease,; IMG reference gene:2504121318; PFAM: Trypsin YP_004264240.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR003660; KEGG: dge:Dgeo_2845 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; ATPase-like, ATP-binding domain; SPTR: Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2504121319; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004264241.1 KEGG: aml:100478532 protein KIAA0649-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504121320 YP_004264242.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: afw:Anae109_3003 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; PRIAM: Succinate-semialdehyde dehydrogenase (NAD(P)(+)); SPTR: Aldehyde dehydrogenase; IMG reference gene:2504121321; PFAM: Aldehyde dehydrogenase family YP_004264243.1 COGs: COG2832 conserved hypothetical protein; InterPro IPR007401; KEGG: dra:DR_1457 hypothetical protein; PFAM: Protein of unknown function DUF454; SPTR: Putative uncharacterized protein; IMG reference gene:2504121322; PFAM: Protein of unknown function (DUF454) YP_004264244.1 KEGG: hmo:HM1_2210 DNA processing protein dpra, putative; SPTR: Putative uncharacterized protein; IMG reference gene:2504121323; PFAM: HTH domain YP_004264245.1 COGs: COG2252 Permease; InterPro IPR006043; KEGG: dge:Dgeo_2607 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; IMG reference gene:2504121324; PFAM: Permease family YP_004264246.1 COGs: COG2409 drug exporter of the RND superfamily; InterPro IPR004869; KEGG: ddr:Deide_21640 hypothetical protein; PFAM: Membrane transport protein, MMPL type; SPTR: Putative uncharacterized protein; IMG reference gene:2504121325; PFAM: MMPL family YP_004264247.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: dra:DR_0026 methyltransferase, putative; PFAM: Methyltransferase type 11; SPTR: Methyltransferase, putative; IMG reference gene:2504121326; PFAM: Methyltransferase domain YP_004264248.1 KEGG: dge:Dgeo_1031 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121327 YP_004264249.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dra:DR_A0350 response regulator PilH, putative; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator PilH, putative; IMG reference gene:2504121328; PFAM: Response regulator receiver domain YP_004264250.1 InterPro IPR002545; KEGG: dra:DR_A0351 hypothetical protein; PFAM: CheW-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121329; PFAM: CheW-like domain YP_004264251.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: dra:DR_A0354 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504121330; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004264252.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: dra:DR_A0354 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504121331; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004264253.1 COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR004105:IPR003594:IPR002545:IPR001789; KEGG: dra:DR_A0355 CheA-related protein; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; CheW-like protein; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; CheW-like protein; SPTR: CheA signal transduction histidine kinase; IMG reference gene:2504121332; PFAM: CheW-like domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain YP_004264254.1 KEGG: dra:DR_A0356 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121333 YP_004264255.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dra:DR_A0357 response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator; IMG reference gene:2504121334; PFAM: Response regulator receiver domain YP_004264256.1 COGs: COG2323 membrane protein; InterPro IPR007353; KEGG: cat:CA2559_11408 hypothetical protein; PFAM: Protein of unknown function DUF421; SPTR: Putative uncharacterized protein; IMG reference gene:2504121335; PFAM: Protein of unknown function (DUF421) YP_004264257.1 COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: ddr:Deide_20540 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504121336; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase YP_004264258.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: dge:Dgeo_1034 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase-related protein; IMG reference gene:2504121337; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004264259.1 KEGG: dra:DR_2528 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504121338 YP_004264260.1 COGs: COG2021 Homoserine acetyltransferase; InterPro IPR000073:IPR008220; KEGG: dge:Dgeo_0517 homoserine O-acetyltransferase; PFAM: Alpha/beta hydrolase fold-1; PRIAM: Homoserine O-acetyltransferase; SPTR: Homoserine O-acetyltransferase; TIGRFAM: Homoserine acetyltransferase; IMG reference gene:2504121339; PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase YP_004264261.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277:IPR006235; KEGG: dge:Dgeo_0518 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; IMG reference gene:2504121340; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_004264262.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: tra:Trad_2518 5,10-methylenetetrahydrofolate reductase-related protein; PFAM: Methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; IMG reference gene:2504121341; PFAM: Methylenetetrahydrofolate reductase YP_004264263.1 COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR003726:IPR000489:IPR003759:IPR006158:IPR004223:IPR0118 22; KEGG: tra:Trad_2519 methionine synthase; PFAM: Homocysteine S-methyltransferase; Pterin-binding; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding; Vitamin B12-dependent methionine synthase, activation domain; PRIAM: Methionine synthase; SPTR: Methionine synthase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase; IMG reference gene:2504121342; PFAM: Pterin binding enzyme; Vitamin B12 dependent methionine synthase, activation domain; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase YP_004264264.1 COGs: COG0814 Amino acid permease; InterPro IPR018227; KEGG: apa:APP7_0643 tyrosine-specific transport protein 2; PFAM: Tryptophan/tyrosine permease; SPTR: Tyrosine-specific transport protein 2; IMG reference gene:2504121343; PFAM: Tryptophan/tyrosine permease family YP_004264265.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dra:DR_2198 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504121344; PFAM: ABC transporter YP_004264266.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: dra:DR_2197 ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, permease protein, CysTW family; IMG reference gene:2504121345; PFAM: Binding-protein-dependent transport system inner membrane component YP_004264267.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR015168:IPR010067; KEGG: dge:Dgeo_0543 ABC transporter, substrate-binding protein, aliphatic sulphonates; SPTR: ABC transporter, substrate-binding protein, aliphatic sulphonate; TIGRFAM: ABC transporter, substrate-binding protein, aliphatic sulphonates; IMG reference gene:2504121346; PFAM: NMT1/THI5 like; TIGRFAM: ABC transporter, substrate-binding protein, aliphatic sulfonates family YP_004264268.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR002772; KEGG: aac:Aaci_0332 glycoside hydrolase family 3 domain protein; PFAM: Glycoside hydrolase, family 3, N-terminal; Glycoside hydrolase, family 3, C-terminal; PRIAM: Beta-glucosidase; SPTR: Glycoside hydrolase family 3 domain protein; IMG reference gene:2504121347; PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain YP_004264269.1 COGs: COG1540 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0271, LamB/YcsF; InterPro IPR005501; KEGG: dra:DR_A0284 LamB/YcsF family protein; PFAM: Uncharacterised protein family UPF0271, LamB/YcsF; SPTR: UPF0271 protein DR_A0284; IMG reference gene:2504120630; PFAM: LamB/YcsF family YP_004264270.1 COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003833:IPR003778:IPR010016; KEGG: msv:Mesil_1829 allophanate hydrolase subunit 2; PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; Allophanate hydrolase subunit 2; SPTR: Allophanate hydrolase subunit 2; TIGRFAM: Conserved hypothetical protein CHP00370; IMG reference gene:2504120631; PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; TIGRFAM: TIGR00370 family protein; biotin-dependent carboxylase uncharacterized domain YP_004264271.1 COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; KEGG: gmc:GY4MC1_1586 natural resistance-associated macrophage protein; SPTR: Putative transmembrane transport protein; IMG reference gene:2504120632; PFAM: Natural resistance-associated macrophage protein YP_004264272.1 COGs: COG2301 Citrate lyase beta subunit; InterPro IPR005000; KEGG: dge:Dgeo_0359 citryl-CoA lyase; PFAM: Aldehyde-lyase domain; PRIAM: Citryl-CoA lyase; SPTR: Citryl-CoA lyase; IMG reference gene:2504120633; PFAM: HpcH/HpaI aldolase/citrate lyase family YP_004264273.1 COGs: COG5534 Plasmid replication initiator protein; KEGG: dra:DR_B0145 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120634; PFAM: Replication initiator protein A YP_004264274.1 COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: pap:PSPA7_4326 hypothetical protein; PFAM: Glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase; TIGRFAM: Glycerate kinase; IMG reference gene:2504120635; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase YP_004264275.1 COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterPro IPR013655:IPR003661:IPR003594:IPR000014; KEGG: ddr:Deide_21610 putative histidine kinase, classic; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: Putative histidine kinase, classic; TIGRFAM: PAS; IMG reference gene:2504120636; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; TIGRFAM: PAS domain S-box YP_004264276.1 COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: dra:DR_1032 GufA protein; PFAM: Zinc/iron permease; SPTR: GufA protein; IMG reference gene:2504120637; PFAM: ZIP Zinc transporter YP_004264277.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dra:DR_B0093 GGDEF family protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF family protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504120638; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004264278.1 COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; HAMAP: DNA polymerase IV; InterPro IPR022880:IPR001126; KEGG: pde:Pden_0732 DNA-directed DNA polymerase; PFAM: DNA-repair protein, UmuC-like; PRIAM: DNA-directed DNA polymerase; SPTR: DNA polymerase IV; IMG reference gene:2504120639; PFAM: impB/mucB/samB family C-terminal; IMS family HHH motif; impB/mucB/samB family YP_004264279.1 COGs: COG2855 membrane protein; InterPro IPR018383:IPR004630; KEGG: pap:PSPA7_6170 hypothetical protein; PFAM: Uncharacterised protein family UPF0324, prokaryote; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0324, bacteria; IMG reference gene:2504120640; PFAM: Conserved hypothetical protein 698; TIGRFAM: conserved hypothetical integral membrane protein YP_004264280.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: ddr:Deide_18390 putative transcriptional regulator, MarR; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Putative transcriptional regulator, MarR; IMG reference gene:2504120641; PFAM: MarR family YP_004264281.1 InterPro IPR004360; KEGG: ddr:Deide_18380 putative lactoylgluathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative lactoylgluathione lyase; IMG reference gene:2504120642; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004264282.1 InterPro IPR004360; KEGG: ddr:Deide_18370 putative glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative glyoxalase/bleomycin resistance protein/dioxygenase; IMG reference gene:2504120643; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004264283.1 COGs: COG0400 esterase; InterPro IPR003140; KEGG: ddr:Deide_18360 putative esterase; PFAM: Phospholipase/carboxylesterase; SPTR: Putative esterase; IMG reference gene:2504120644; PFAM: Phospholipase/Carboxylesterase YP_004264284.1 KEGG: amr:AM1_3381 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120645 YP_004264285.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048:IPR022290; KEGG: dge:Dgeo_1252 luciferase-like protein; PFAM: Luciferase-like, subgroup; SPTR: Flavin dependent monooxygenase; TIGRFAM: Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative; IMG reference gene:2504120646; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable oxidoreductase, LLM family YP_004264286.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: cyn:Cyan7425_0013 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Predicted protein; IMG reference gene:2504120647; PFAM: Major Facilitator Superfamily YP_004264287.1 COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: gau:GAU_2187 putative soluble quinone reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Putative soluble quinone reductase; IMG reference gene:2504120648; PFAM: NADPH-dependent FMN reductase YP_004264288.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: swi:Swit_1788 amidohydrolase 2; PFAM: Amidohydrolase 2; SPTR: Amidohydrolase 2; IMG reference gene:2504120649; PFAM: Amidohydrolase YP_004264289.1 COGs: COG2388 acetyltransferase; KEGG: dra:DR_1844 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120650; PFAM: Acetyltransferase (GNAT) family YP_004264290.1 COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: bgl:bglu_2g02920 isochorismatase hydrolase; PFAM: Isochorismatase-like; SPTR: Isochorismatase hydrolase; IMG reference gene:2504120651; PFAM: Isochorismatase family YP_004264291.1 KEGG: prw:PsycPRwf_0104 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120652 YP_004264292.1 COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; InterPro IPR018946:IPR006311; KEGG: npu:Npun_R0280 alkaline phosphatase; PFAM: Alkaline phosphatase D-related; PRIAM: Alkaline phosphatase; SPTR: Alkaline phosphatase; IMG reference gene:2504120653; PFAM: PhoD-like phosphatase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004264293.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dra:DR_A0242 hypothetical protein; PFAM: Transcription regulator Rrf2; SPTR: Putative uncharacterized protein; TIGRFAM: Transcription regulator Rrf2; IMG reference gene:2504120654; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004264294.1 COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR011717:IPR000160:IPR001633:IPR019734; KEGG: ddr:Deide_16860 putative C-di-GMP phosphodiesterase A; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide TPR-4; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative c-di-GMP phosphodiesterase A; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504120655; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004264295.1 COGs: COG1017 Hemoglobin-like flavoprotein; HAMAP: Flavohemoprotein; InterPro IPR000971:IPR008333:IPR001433; KEGG: dra:DR_A0243 flavohemoprotein; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Globin, subset; PRIAM: Nitric oxide dioxygenase; SPTR: Flavohemoprotein; IMG reference gene:2504120656; PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; Globin YP_004264296.1 COGs: COG1292 Choline-glycine betaine transporter; InterPro IPR000060; KEGG: bbe:BBR47_13120 glycine betaine transporter; PFAM: BCCT transporter; SPTR: Glycine betaine transporter; TIGRFAM: BCCT transporter; IMG reference gene:2504120657; PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_004264297.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: dge:Dgeo_2477 conjugal plasmid transfer ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: ATPase involved in plasmide/chromosome partitioning, ParA/Soj-like protein; IMG reference gene:2504120658; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004264298.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: ana:alr8007 ParB family chromosome partitioning protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein; IMG reference gene:2504120659; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004264299.1 KEGG: gvi:glr2981 hypothetical protein; SPTR: Glr2981 protein; IMG reference gene:2504120662 YP_004264300.1 COGs: COG2200 FOG: EAL domain; InterPro IPR013105:IPR001440:IPR000160:IPR001633:IPR019734; KEGG: dra:DR_2299 GGDEF family protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: GGDEF family protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504120663; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004264301.1 COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: ddr:Deide_18560 putative MscS mechanosensitive ion channel; putative membrane protein; PFAM: Mechanosensitive ion channel MscS; SPTR: Putative mscS mechanosensitive ion channel; putative membrane protein; IMG reference gene:2504120664; PFAM: Mechanosensitive ion channel YP_004264302.1 KEGG: ddr:Deide_2p00550 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120665 YP_004264303.1 COGs: COG3211 phosphatase; InterPro IPR008557:IPR006311; KEGG: ddr:Deide_2p00560 putative phosphatase, precursor; PFAM: Protein of unknown function DUF839; SPTR: Putative phosphatase,; IMG reference gene:2504120666; PFAM: Bacterial protein of unknown function (DUF839) YP_004264304.1 COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; HAMAP: Manganese transport protein MntH; InterPro IPR023056:IPR001046; KEGG: dge:Dgeo_0709 manganese transport protein MntH; PFAM: Natural resistance-associated macrophage protein; SPTR: NRAMP family Mn2+/Fe2+ transporter; TIGRFAM: Natural resistance-associated macrophage protein; IMG reference gene:2504120667; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters YP_004264305.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR002912:IPR006236; KEGG: pde:Pden_0814 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2504120668; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase YP_004264306.1 COGs: COG1932 Phosphoserine aminotransferase; InterPro IPR000192:IPR006271; KEGG: rsh:Rsph17029_0019 phosphoserine aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Phosphoserine transaminase; SPTR: Aminotransferase; TIGRFAM: Phosphoserine aminotransferase, Methanosarcina-type; IMG reference gene:2504120669; TIGRFAM: phosphoserine aminotransferase, Methanosarcina type; phosphoserine aminotransferase, putative YP_004264307.1 COGs: COG0560 Phosphoserine phosphatase; InterPro IPR005834:IPR004469:IPR006383; KEGG: sil:SPO3353 phosphoserine phosphatase; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoserine phosphatase; SPTR: Phosphoserine phosphatase SerB; TIGRFAM: Phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB, PSPase-like; IMG reference gene:2504120670; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB YP_004264308.1 KEGG: rba:RB8078 arylsulfatase A [precursor]; SPTR: Arylsulfatase A [precursor]; IMG reference gene:2504120671 YP_004264309.1 KEGG: dge:Dgeo_2514 tetratricopeptide TPR_2; SPTR: Tetratricopeptide TPR_2; IMG reference gene:2504120672 YP_004264310.1 COGs: COG2378 transcriptional regulator protein; KEGG: dge:Dgeo_2515 helix-turn-helix, type 11; SPTR: Helix-turn-helix, type 11; IMG reference gene:2504120673; PFAM: HTH domain YP_004264311.1 COGs: COG1203 helicase; InterPro IPR001650:IPR014001:IPR006483:IPR006474; KEGG: dge:Dgeo_2629 CRISPR-associated helicase Cas3 family protein protein; PFAM: Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: CRISPR-associated helicase Cas3, core; TIGRFAM: Helicase Cas3, CRISPR-associated, core; CRISPR-associated HD domain; IMG reference gene:2504120674; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD YP_004264312.1 InterPro IPR013381; KEGG: dge:Dgeo_2630 CRISPR-associated CSE1 family protein; PFAM: CRISPR-associated protein Cse1; SPTR: CRISPR-associated protein Cse1; TIGRFAM: CRISPR-associated protein Cse1; IMG reference gene:2504120675; PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 YP_004264313.1 InterPro IPR002559; KEGG: ddr:Deide_06540 putative transposase; PFAM: Transposase, IS4-like; SPTR: Putative transposase; IMG reference gene:2504120676; PFAM: Transposase DDE domain YP_004264314.1 KEGG: dge:Dgeo_2630 CRISPR-associated CSE1 family protein; IMG reference gene:2504120677 YP_004264315.1 InterPro IPR013382; KEGG: dge:Dgeo_2631 hypothetical protein; PFAM: CRISPR-associated protein Cse2; SPTR: CRISPR-associated protein; TIGRFAM: CRISPR-associated protein Cse2; IMG reference gene:2504120678; PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 YP_004264316.1 InterPro IPR002559; KEGG: dge:Dgeo_1090 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4; IMG reference gene:2504120680 YP_004264317.1 InterPro IPR010147:IPR013422; KEGG: dge:Dgeo_2633 CRISPR-associated Cas5e family protein; SPTR: CRISPR-associated protein, CT1976; TIGRFAM: CRISPR-associated protein, Cas5e-type; CRISPR-associated protein Cas5, N-terminal domain; IMG reference gene:2504120681; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI; CRISPR-associated protein Cas5, N-terminal domain YP_004264318.1 InterPro IPR010179; KEGG: dge:Dgeo_2634 CRISPR-associated CSE3 family protein; PFAM: CRISPR-associated protein, CT1974; SPTR: CRISPR-associated protein, CT1974; TIGRFAM: CRISPR-associated protein, CT1974; IMG reference gene:2504120682; PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI YP_004264319.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729:IPR019851; KEGG: dge:Dgeo_2636 CRISPR-associated Cas1 family protein; PFAM: CRISPR-associated protein Cas1; SPTR: CRISPR-associated protein Cas1; TIGRFAM: CRISPR-associated protein Cas1, ECOLI subtype; CRISPR-associated protein Cas1; IMG reference gene:2504120683; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI; CRISPR-associated endonuclease Cas1 YP_004264320.1 InterPro IPR010152; KEGG: dge:Dgeo_2637 CRISPR-associated Cas2 family protein; PFAM: CRISPR-associated protein Cas2 subtype; SPTR: CRISPR-associated protein Cas2; TIGRFAM: CRISPR-associated protein Cas2 subtype; IMG reference gene:2504120684; PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI YP_004264321.1 KEGG: spe:Spro_2887 carbohydrate-binding CenC domain-containing protein; SPTR: Carbohydrate-binding CenC domain protein; IMG reference gene:2504120685 YP_004264322.1 KEGG: spe:Spro_2887 carbohydrate-binding CenC domain-containing protein; SPTR: Carbohydrate-binding CenC domain protein; IMG reference gene:2504120686 YP_004264323.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: bbe:BBR47_42570 membrane-bound protein LytR; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Membrane-bound protein LytR; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504120687; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004264324.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: ank:AnaeK_4418 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; manually curated; IMG reference gene:2504120688; PFAM: Polysaccharide biosynthesis protein YP_004264325.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ank:AnaeK_4421 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2504120689; PFAM: Glycosyl transferases group 1 YP_004264326.1 KEGG: bpf:BpOF4_06535 hypothetical protein; SPTR: O-antigen polymerase; IMG reference gene:2504120690; PFAM: O-Antigen ligase YP_004264327.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: rrs:RoseRS_3642 glycosyl transferase, group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1; IMG reference gene:2504120691; PFAM: Glycosyl transferases group 1 YP_004264328.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: afw:Anae109_2631 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2504120692; PFAM: Glycosyl transferases group 1 YP_004264329.1 COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509:IPR005886; KEGG: mrb:Mrub_2141 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; manually curated; IMG reference gene:2504120693; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase YP_004264330.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856; KEGG: dge:Dgeo_0342 protein-tyrosine kinase; PFAM: Lipopolysaccharide biosynthesis; SPTR: Protein-tyrosine kinase; IMG reference gene:2504120694; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain YP_004264331.1 KEGG: mrb:Mrub_1489 metal dependent phosphohydrolase; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504120695 YP_004264332.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017475; KEGG: ttj:TTHA0642 putative glycosyltransferase; PFAM: Bacterial sugar transferase; SPTR: Putative uncharacterized protein; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; IMG reference gene:2504120696; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_004264333.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dge:Dgeo_1110 oxidoreductase-like protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase-like protein; IMG reference gene:2504120697; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold YP_004264334.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: dge:Dgeo_2759 ABC transporter-related protein; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type Fe3+-siderophore transport system, ATPase component; IMG reference gene:2504120698; PFAM: ABC transporter YP_004264335.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: dra:DR_B0122 iron ABC transporter, permease protein; PFAM: ABC transporter permease protein; SPTR: Iron ABC transporter, permease protein; IMG reference gene:2504120699; PFAM: FecCD transport family YP_004264336.1 COGs: COG4594 ABC-type Fe3+-citrate transport system periplasmic component; InterPro IPR002491; KEGG: mrb:Mrub_2416 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504120700; PFAM: Periplasmic binding protein YP_004264337.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: ddr:Deide_2p00370 putative Fe3+-siderophore ABC transporter, permease component; PFAM: ABC transporter permease protein; SPTR: Putative Fe3+-siderophore ABC transporter, permease component; IMG reference gene:2504120701; PFAM: FecCD transport family YP_004264338.1 COGs: COG4759 Uncharacterized protein containing thioredoxin-like domain; InterPro IPR009737; KEGG: ddr:Deide_2p00361 putative sucrase/ferredoxin-like protein; PFAM: Sucraseferredoxin-like; SPTR: Putative sucrase/ferredoxin-like protein; IMG reference gene:2504120702; PFAM: Sucrase/ferredoxin-like YP_004264339.1 COGs: COG4594 ABC-type Fe3+-citrate transport system periplasmic component; InterPro IPR002491; KEGG: ddr:Deide_21930 putative ABC transporter, periplasmic component; PFAM: Periplasmic binding protein; SPTR: Putative ABC transporter, periplasmic component; IMG reference gene:2504120703; PFAM: Periplasmic binding protein YP_004264340.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dge:Dgeo_2753 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: ABC-type Fe3+-siderophore transport system, periplasmic component; IMG reference gene:2504120704; PFAM: Periplasmic binding protein YP_004264341.1 COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: ddr:Deide_07910 putative CoA-transferase; PFAM: CoA-transferase family III; SPTR: CAIB/BAIF family; IMG reference gene:2504120706; PFAM: CoA-transferase family III YP_004264342.1 COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: dra:DR_A0237 oxidoreductase; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; PRIAM: Xanthine dehydrogenase; SPTR: Oxidoreductase; IMG reference gene:2504120707; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain YP_004264343.1 COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR005107; KEGG: dra:DR_A0236 oxidoreductase; PFAM: Molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein, C-terminal; PRIAM: Xanthine dehydrogenase; SPTR: Oxidoreductase; IMG reference gene:2504120708; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain YP_004264344.1 COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: dra:DR_A0235 oxidoreductase, iron-sulfur subunit; PFAM: [2Fe-2S]-binding; Ferredoxin; SPTR: Oxidoreductase, iron-sulfur subunit; IMG reference gene:2504120709; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain YP_004264345.1 COGs: COG3798 conserved hypothetical protein; InterPro IPR018684; KEGG: dra:DR_1348 hypothetical protein; PFAM: Protein of unknown function DUF2171; SPTR: Putative uncharacterized protein; IMG reference gene:2504120710; PFAM: Uncharacterized protein conserved in bacteria (DUF2171) YP_004264346.1 COGs: COG2323 membrane protein; InterPro IPR007353; KEGG: dra:DR_0048 hypothetical protein; PFAM: Protein of unknown function DUF421; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504120711; PFAM: Protein of unknown function (DUF421) YP_004264347.1 COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR010505:IPR006638:IPR013483; KEGG: ddr:Deide_05940 putative molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum cofactor synthesis C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: Molybdenum cofactor biosynthesis protein A; IMG reference gene:2504120712; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial YP_004264348.1 COGs: COG0368 Cobalamin-5-phosphate synthase; HAMAP: Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; InterPro IPR003805; KEGG: dge:Dgeo_2367 cobalamin-5-phosphate synthase CobS; PFAM: Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; SPTR: Cobalamin synthase; IMG reference gene:2504120713; PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase YP_004264349.1 COGs: COG2038 NaMN:DMB phosphoribosyltransferase; HAMAP: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic; InterPro IPR017846:IPR003200; KEGG: dra:DR_A0240 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like; PRIAM: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; SPTR: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic; IMG reference gene:2504120714; PFAM: Phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_004264350.1 COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: dge:Dgeo_2873 cobalbumin biosynthesis enzyme; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase, CobU; IMG reference gene:2504120715; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase YP_004264351.1 IMG reference gene:2504120716 YP_004264352.1 COGs: COG1797 Cobyrinic acid a c-diamide synthase; HAMAP: Cobyrinic acid a,c-diamide synthase CbiA; InterPro IPR004484:IPR002586:IPR011698; KEGG: ddr:Deide_2p01690 putative cobyrinic acid A,C-diamide synthase; PFAM: CobB/CobQ-like glutamine amidotransferase; Cobyrinic acid a,c-diamide synthase; SPTR: Putative cobyrinic acid A,C-diamide synthase; TIGRFAM: Cobyrinic acid a,c-diamide synthase CbiA; IMG reference gene:2504120717; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase YP_004264353.1 COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: dra:DR_B0008 cob(I)alamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)alamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; IMG reference gene:2504120718; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase YP_004264354.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dge:Dgeo_2363 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: ABC-type Fe3+-hydroxamate transport system, periplasmic component; IMG reference gene:2504120719; PFAM: Periplasmic binding protein YP_004264355.1 KEGG: ddr:Deide_05001 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein; IMG reference gene:2504120720 YP_004264356.1 COGs: COG2872 metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain; InterPro IPR018164:IPR012947:IPR003156; KEGG: dge:Dgeo_1201 threonyl/alanyl tRNA synthetase, SAD; PFAM: Phosphoesterase, DHHA1; Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Threonyl/alanyl tRNA synthetase, SAD; IMG reference gene:2504120721; PFAM: tRNA synthetases class II (A) YP_004264357.1 InterPro IPR000073; KEGG: bfa:Bfae_05870 prolyl aminopeptidase 2; PFAM: Alpha/beta hydrolase fold-1; PRIAM: Prolyl aminopeptidase; SPTR: Prolyl aminopeptidase 2; IMG reference gene:2504120722; PFAM: alpha/beta hydrolase fold YP_004264358.1 COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR006059:IPR005950; KEGG: bvi:Bcep1808_6031 molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: Molybdenum ABC transporter, periplasmic binding protein; IMG reference gene:2504120723; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein YP_004264359.1 COGs: COG4149 ABC-type molybdate transport system permease component; InterPro IPR000515:IPR011867; KEGG: sml:Smlt2765 putative ABC molybdenum transport-related membrane protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Putative ABC molybdenum transport-related membrane protein; TIGRFAM: Molybdate ABC transporter, permease protein; IMG reference gene:2504120724; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: molybdate ABC transporter, permease protein YP_004264360.1 COGs: COG1118 ABC-type sulfate/molybdate transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: rso:RS05462 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Molybdate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Molybdate ABC transporter ATP-binding protein; IMG reference gene:2504120725; PFAM: ABC transporter YP_004264361.1 COGs: COG1435 Thymidine kinase; HAMAP: Thymidine kinase, subgroup; InterPro IPR020634:IPR001267; KEGG: dge:Dgeo_0578 thymidine kinase; PFAM: Thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; IMG reference gene:2504120726; PFAM: Thymidine kinase YP_004264362.1 COGs: COG5339 conserved hypothetical protein; InterPro IPR010352; KEGG: dra:DR_2196 hypothetical protein; PFAM: Protein of unknown function DUF945; SPTR: Putative uncharacterized protein; IMG reference gene:2504120727; PFAM: Bacterial protein of unknown function (DUF945) YP_004264363.1 COGs: COG3232 5-carboxymethyl-2-hydroxymuconate isomerase; InterPro IPR004220; KEGG: dra:DR_A0227 5-carboxymethyl-2-hydroxymuconate isomerase; PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; SPTR: 5-carboxymethyl-2-hydroxymuconate isomerase; IMG reference gene:2504120729; PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase YP_004264364.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR012684; KEGG: dra:DR_A0226 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase; PFAM: Fumarylacetoacetase, C-terminal-like; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; IMG reference gene:2504120730; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit YP_004264365.1 InterPro IPR004360:IPR011981; KEGG: dra:DR_A0224 homoprotocatechuate 2,3-dioxygenase, putative; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: Catechol 2,3-dioxygenase; SPTR: Homoprotocatechuate 2,3-dioxygenase, putative; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpaD; IMG reference gene:2504120731; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_004264366.1 COGs: COG2368 Aromatic ring hydroxylase; InterPro IPR004925:IPR012687; KEGG: dra:DR_A0223 4-hydroxyphenylacetate-3-hydroxylase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; SPTR: 4-hydroxyphenylacetate-3-hydroxylase; TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; IMG reference gene:2504120732; PFAM: 4-hydroxyphenylacetate 3-hydroxylase N terminal; 4-hydroxyphenylacetate 3-hydroxylase C terminal; TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component YP_004264367.1 COGs: COG2852 conserved hypothetical protein; InterPro IPR007569; KEGG: dra:DR_0221 hypothetical protein; PFAM: Domain of unknown function DUF559; SPTR: Putative uncharacterized protein; IMG reference gene:2504120733; PFAM: Protein of unknown function (DUF559) YP_004264368.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: dra:DR_A0222 TDP-glucose-4,6-dehydratase-related protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: TDP-glucose-4,6-dehydratase-related protein; IMG reference gene:2504120734; PFAM: NAD dependent epimerase/dehydratase family YP_004264369.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR011985; KEGG: dra:DR_A0220 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; PRIAM: Betaine-aldehyde dehydrogenase; SPTR: Aldehyde dehydrogenase; TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; IMG reference gene:2504120735; PFAM: Aldehyde dehydrogenase family; TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_004264370.1 KEGG: dra:DR_A0219 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504120736 YP_004264371.1 COGs: COG3280 Maltooligosyl trehalose synthase; InterPro IPR006047:IPR006589:IPR012767; KEGG: krh:KRH_06560 maltooligosyl trehalose synthase; PFAM: Glycosyl hydrolase, family 13, catalytic domain; PRIAM: (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Trehalose maltooligosyl trehalose synthase; TIGRFAM: Malto-oligosyltrehalose synthase; IMG reference gene:2504120737; PFAM: Alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose synthase YP_004264372.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dra:DR_B0093 GGDEF family protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF family protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504120738; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004264373.1 COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: dra:DR_A0123 arsenate reductase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Arsenate reductase; IMG reference gene:2504120739; PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_004264374.1 InterPro IPR004843; KEGG: dge:Dgeo_2771 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; IMG reference gene:2504120741 YP_004264375.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: ddr:Deide_2p00101 putative transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Putative transcriptional regulator, ArsR family; IMG reference gene:2504120742; PFAM: Bacterial regulatory protein, arsR family YP_004264376.1 InterPro IPR001789; KEGG: dge:Dgeo_0043 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Receiver domain REC; IMG reference gene:2504120743; PFAM: Response regulator receiver domain YP_004264377.1 COGs: COG2346 Truncated hemoglobins; InterPro IPR001486; KEGG: dge:Dgeo_0779 globin; PFAM: Globin, truncated bacterial-like; SPTR: Globin; IMG reference gene:2504120744; PFAM: Bacterial-like globin