-- dump date 20140619_055809 -- class Genbank::CDS -- table cds_note -- id note YP_001213471.1 TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator, DnaA C-terminal domain; Chromosomal replication initiator, DnaA; SMART: AAA ATPase YP_001213472.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001213473.1 TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001213474.1 TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001213475.1 TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001213476.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001213477.1 PFAM: Saccharopine dehydrogenase YP_001213478.1 PFAM: protein of unknown function DUF205 YP_001213479.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001213480.1 PFAM: UMUC domain protein DNA-repair protein YP_001213481.1 PFAM: protein of unknown function DUF951 YP_001213482.1 TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase YP_001213485.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001213488.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001213489.1 PFAM: ferric-uptake regulator YP_001213493.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein YP_001213495.1 PFAM: TrkA-N domain protein; TrkA-C domain protein YP_001213496.1 PFAM: TrkA-N domain protein YP_001213497.1 PFAM: UspA domain protein YP_001213498.1 PFAM: cation transporter YP_001213499.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001213500.1 PFAM: protein of unknown function DUF47 YP_001213501.1 PFAM: phosphate transporter YP_001213502.1 Essential for recycling GMP and indirectly, cGMP YP_001213503.1 PFAM: protein of unknown function DUF370 YP_001213504.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein YP_001213505.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001213508.1 PFAM: Methyltransferase type 11 YP_001213510.1 PFAM: protein of unknown function DUF1025 YP_001213511.1 TIGRFAM: C_GCAxxG_C_C family protein YP_001213512.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001213514.1 TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_001213516.1 PFAM: ROK family protein YP_001213517.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001213518.1 PFAM: Holliday junction resolvase YqgF; SMART: Resolvase, RNase H domain protein fold YP_001213519.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001213520.1 PFAM: iron-containing alcohol dehydrogenase YP_001213521.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001213522.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001213523.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001213524.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001213525.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001213526.1 PFAM: phage integrase family protein YP_001213529.1 PFAM: helix-turn-helix domain protein YP_001213531.1 PFAM: metallophosphoesterase YP_001213543.1 PFAM: Resolvase, N-terminal domain YP_001213547.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B YP_001213548.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001213549.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase YP_001213551.1 PFAM: transposase IS3/IS911 family protein YP_001213552.1 PFAM: Integrase, catalytic region YP_001213559.1 PFAM: single-strand binding protein/Primosomal replication protein n YP_001213561.1 PFAM: helix-turn-helix domain protein YP_001213566.1 PFAM: Resolvase, N-terminal domain YP_001213570.1 PFAM: helix-turn-helix domain protein YP_001213571.1 PFAM: protein of unknown function DUF105 YP_001213573.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213574.1 TIGRFAM: putative ATP binding protein; PFAM: protein of unknown function DUF71, ATP-binding region YP_001213575.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001213576.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein YP_001213577.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001213578.1 PFAM: Radical SAM domain protein YP_001213579.1 TIGRFAM: putative ATP binding protein; PFAM: protein of unknown function DUF71, ATP-binding region YP_001213581.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213582.1 PFAM: protein of unknown function UPF0153 YP_001213583.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001213584.1 PFAM: Integrase, catalytic region YP_001213585.1 PFAM: transposase IS3/IS911 family protein YP_001213588.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213590.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213592.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001213593.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001213594.1 PFAM: TM2 domain containing protein+B7201 YP_001213597.1 PFAM: HI0933 family protein YP_001213599.1 PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase YP_001213600.1 PFAM: Hly-III family protein YP_001213601.1 PFAM: proteinase inhibitor I4, serpin YP_001213602.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: GCN5-related N-acetyltransferase; Radical SAM domain protein YP_001213604.1 PFAM: protein of unknown function DUF134; Sigma-70, region 4 type 2 YP_001213605.1 PFAM: aldo/keto reductase YP_001213606.1 PFAM: LmbE family protein YP_001213607.1 PFAM: multi antimicrobial extrusion protein MatE; polysaccharide biosynthesis protein YP_001213608.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein YP_001213610.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001213611.1 PFAM: glycosyl transferase, group 1 YP_001213612.1 PFAM: glycosyl transferase, family 2 YP_001213614.1 PFAM: glycosyl transferase, family 2 YP_001213615.1 PFAM: sugar isomerase (SIS) YP_001213616.1 PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_001213617.1 PFAM: Nucleotidyl transferase YP_001213618.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001213619.1 PFAM: glycosyl transferase, family 2 YP_001213620.1 TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: glycosyl transferase, family 2; Polynucleotide kinase 3 phosphatase, central region YP_001213621.1 PFAM: glycosyl transferase, group 1 YP_001213622.1 PFAM: Protein of unknown function DUF1616 YP_001213623.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001213624.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain YP_001213626.1 PFAM: protein of unknown function UPF0157 YP_001213627.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001213628.1 TIGRFAM: leucyl-tRNA synthetase YP_001213629.1 TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001213630.1 PFAM: Colicin V production protein YP_001213631.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213632.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001213633.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95 YP_001213634.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001213635.1 PFAM: Polysulphide reductase, NrfD YP_001213637.1 PFAM: Integral membrane protein TerC YP_001213638.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001213639.1 PFAM: Integrase, catalytic region YP_001213642.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213644.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001213645.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001213652.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like YP_001213656.1 PFAM: DNA polymerase III, beta chain YP_001213658.1 PFAM: filamentation induced by cAMP protein Fic YP_001213662.1 PFAM: protein of unknown function DUF192 YP_001213663.1 PFAM: phage integrase family protein YP_001213666.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001213678.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5 YP_001213681.1 PFAM: helix-turn-helix domain protein YP_001213683.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001213685.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001213686.1 PFAM: protein of unknown function DUF6, transmembrane YP_001213687.1 PFAM: protein of unknown function DUF45 YP_001213689.1 PFAM: alpha/beta hydrolase fold YP_001213691.1 TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein YP_001213692.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001213693.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001213694.1 PFAM: low molecular weight phosphotyrosine protein phosphatase YP_001213695.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein YP_001213696.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001213697.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001213698.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component YP_001213699.1 TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001213700.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001213701.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001213702.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001213705.1 PFAM: ornithine cyclodeaminase/mu-crystallin YP_001213706.1 PFAM: Rhomboid family protein YP_001213707.1 PFAM: response regulator receiver YP_001213708.1 PFAM: response regulator receiver YP_001213709.1 PFAM: protein of unknown function UPF0047 YP_001213710.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001213711.1 TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase, family 3 YP_001213712.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001213713.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213715.1 catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate YP_001213716.1 catalyzes the formation of oxaloacetate from pyruvate YP_001213717.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein YP_001213718.1 PFAM: regulatory protein, TetR YP_001213719.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001213720.1 PFAM: ABC-2 type transporter YP_001213721.1 PFAM: ABC-2 type transporter YP_001213722.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213723.1 TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001213724.1 PFAM: nickel-dependent hydrogenase, large subunit YP_001213725.1 TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein YP_001213726.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001213727.1 PFAM: LemA family protein YP_001213728.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001213731.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213732.1 PFAM: Polysulphide reductase, NrfD YP_001213733.1 PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001213735.1 PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_001213737.1 PFAM: transposase IS3/IS911 family protein YP_001213738.1 PFAM: Integrase, catalytic region YP_001213739.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001213740.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Two component regulator propeller; Two component regulator three Y domain protein YP_001213741.1 TIGRFAM: reductive dehalogenase YP_001213744.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001213745.1 PFAM: Radical SAM domain protein YP_001213746.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213749.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213750.1 TIGRFAM: putative ATP binding protein; PFAM: protein of unknown function DUF71, ATP-binding region YP_001213751.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001213752.1 PFAM: ATP-binding region, ATPase domain protein YP_001213753.1 PFAM: transposase IS3/IS911 family protein YP_001213754.1 PFAM: Integrase, catalytic region YP_001213755.1 TIGRFAM: PAS sensor protein; PFAM: histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001213756.1 PFAM: Integrase, catalytic region YP_001213757.1 PFAM: transposase IS3/IS911 family protein YP_001213758.1 PFAM: ATP-binding region, ATPase domain protein YP_001213759.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001213760.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001213763.1 PFAM: helix-turn-helix domain protein YP_001213767.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001213768.1 PFAM: Patatin YP_001213769.1 PFAM: GCN5-related N-acetyltransferase YP_001213770.1 PFAM: protein of unknown function DUF87 YP_001213773.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001213774.1 PFAM: histone deacetylase superfamily YP_001213775.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001213776.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001213777.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001213778.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001213779.1 PFAM: helix-turn-helix domain protein YP_001213780.1 TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001213781.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001213782.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001213783.1 TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040 YP_001213784.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase YP_001213785.1 PFAM: cell division protein FtsA YP_001213786.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001213787.1 PFAM: ATP-cone domain protein YP_001213788.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001213790.1 PFAM: protein of unknown function DUF88 YP_001213791.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001213792.1 PFAM: GatB/Yqey domain protein YP_001213793.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001213796.1 PFAM: phage portal protein, SPP1 YP_001213805.1 PFAM: protein of unknown function DUF164 YP_001213809.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001213810.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001213811.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001213812.1 PFAM: Inorganic pyrophosphatase YP_001213813.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001213814.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001213815.1 PFAM: PDZ/DHR/GLGF domain protein; peptidase M50 YP_001213816.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001213817.1 PFAM: phosphatidate cytidylyltransferase YP_001213818.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001213819.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001213820.1 Catalyzes the phosphorylation of UMP to UDP YP_001213821.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001213822.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001213823.1 TIGRFAM: phosphoribosylformylglycinamidine synthase I YP_001213824.1 TIGRFAM: phosphoribosylformylglycinamidine synthase II; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001213825.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_001213826.1 PFAM: Rieske [2Fe-2S] domain protein YP_001213828.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001213829.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001213831.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001213832.1 PFAM: Polyprenyl synthetase YP_001213833.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001213834.1 PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2 YP_001213835.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein YP_001213836.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001213837.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: peptidase M22, glycoprotease; Haloacid dehalogenase domain protein hydrolase YP_001213838.1 PFAM: protein of unknown function UPF0079 YP_001213839.1 TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001213840.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001213841.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001213842.1 PFAM: 3-dehydroquinate synthase YP_001213843.1 PFAM: UbiA prenyltransferase YP_001213844.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001213845.1 PFAM: metallophosphoesterase YP_001213846.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001213847.1 TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_001213848.1 PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein YP_001213850.1 PFAM: Ion transport protein; Ion transport 2 domain protein YP_001213851.1 PFAM: Polynucleotide adenylyltransferase region YP_001213852.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001213853.1 PFAM: ABC-2 type transporter YP_001213855.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001213856.1 PFAM: diacylglycerol kinase, catalytic region YP_001213859.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001213860.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001213861.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor YP_001213862.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001213863.1 PFAM: Mg2+ transporter protein, CorA family protein YP_001213864.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165 YP_001213866.1 PFAM: protein of unknown function DUF82 YP_001213867.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein YP_001213868.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001213869.1 TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001213870.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001213871.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001213872.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001213874.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001213875.1 TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_001213876.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001213877.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily YP_001213878.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001213879.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase YP_001213881.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001213882.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001213883.1 TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC YP_001213884.1 PFAM: protein of unknown function DUF28 YP_001213885.1 TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase YP_001213886.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001213887.1 PFAM: carboxyl transferase YP_001213888.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_001213889.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_001213890.1 PFAM: isocitrate/isopropylmalate dehydrogenase YP_001213891.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001213893.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid YP_001213894.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region YP_001213895.1 PFAM: histidine triad (HIT) protein YP_001213896.1 PFAM: NUDIX hydrolase YP_001213897.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_001213898.1 PFAM: ATP-NAD/AcoX kinase YP_001213900.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_001213901.1 PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein YP_001213902.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001213903.1 TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) YP_001213904.1 PFAM: shikimate kinase YP_001213905.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001213906.1 TIGRFAM: 3-dehydroquinate dehydratase, type I; PFAM: dehydroquinase class I YP_001213907.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001213908.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001213910.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001213911.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001213912.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001213913.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001213914.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001213915.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001213916.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001213917.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001213918.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001213919.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001213920.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001213921.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001213922.1 one of the stabilizing components for the large ribosomal subunit YP_001213923.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001213924.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001213925.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001213926.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001213927.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_001213928.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001213929.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001213930.1 binds 5S rRNA along with protein L5 and L25 YP_001213931.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001213932.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001213933.1 late assembly protein YP_001213934.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001213935.1 PFAM: adenylate kinase YP_001213936.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001213937.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001213938.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001213939.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001213940.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001213941.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001213942.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001213943.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001213944.1 TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase YP_001213945.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001213946.1 forms a direct contact with the tRNA during translation YP_001213948.1 catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate YP_001213949.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001213951.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001213952.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001213956.1 TIGRFAM: methylthioadenosine phosphorylase; PFAM: purine phosphorylase, family 2 YP_001213957.1 TIGRFAM: putative translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related YP_001213958.1 PFAM: ABC-2 type transporter YP_001213959.1 TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001213961.1 PFAM: MaoC domain protein dehydratase YP_001213962.1 PFAM: GCN5-related N-acetyltransferase YP_001213963.1 PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein YP_001213964.1 PFAM: protein of unknown function DUF75 YP_001213965.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001213966.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001213967.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001213968.1 PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001213969.1 PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001213970.1 TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: glutamine amidotransferase, class-II; sugar isomerase (SIS) YP_001213971.1 PFAM: PEBP family protein YP_001213972.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001213973.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001213975.1 PFAM: PSP1 domain protein YP_001213976.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001213977.1 PFAM: IstB domain protein ATP-binding protein; Chromosomal replication initiator, DnaA; SMART: AAA ATPase YP_001213978.1 TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region YP_001213979.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase YP_001213980.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001213981.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase YP_001213982.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001213983.1 TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type YP_001213984.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20 YP_001213985.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001213986.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001213987.1 PFAM: helix-turn-helix domain protein YP_001213988.1 PFAM: SMC domain protein YP_001213989.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor RpoD domain protein; PFAM: Bacterio-opsin activator, HTH domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2 YP_001213990.1 TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_001213991.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001213992.1 TIGRFAM: phosphoenolpyruvate synthase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region YP_001213993.1 PFAM: protein of unknown function DUF151 YP_001213995.1 TIGRFAM: ATP synthase F0, A subunit; PFAM: H+-transporting two-sector ATPase, A subunit YP_001213996.1 TIGRFAM: ATP synthase F0, C subunit; PFAM: H+-transporting two-sector ATPase, C subunit YP_001213997.1 TIGRFAM: ATP synthase F0, B subunit; PFAM: H+-transporting two-sector ATPase, B/B' subunit YP_001213998.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001213999.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001214000.1 TIGRFAM: ATP synthase F1, gamma subunit; PFAM: H+-transporting two-sector ATPase, gamma subunit YP_001214001.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001214002.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001214003.1 TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein YP_001214005.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001214006.1 PFAM: Endonuclease V YP_001214007.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein YP_001214009.1 PFAM: DNA repair protein RadC YP_001214010.1 PFAM: extracellular solute-binding protein, family 5 YP_001214012.1 PFAM: aminotransferase, class I and II YP_001214013.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001214014.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001214016.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO YP_001214019.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA family protein YP_001214020.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001214021.1 PFAM: conserved hypothetical protein 103 YP_001214022.1 TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001214027.1 PFAM: Tubulin/FtsZ, GTPase YP_001214028.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001214029.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component YP_001214031.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001214033.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001214034.1 TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: Helix-hairpin-helix DNA-binding, class 1; NAD-dependent DNA ligase-like YP_001214035.1 PFAM: uncharacterised conserved protein UCP033563 YP_001214036.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_001214037.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001214038.1 PFAM: aminotransferase, class V YP_001214039.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001214040.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase YP_001214041.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001214042.1 TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 4; SMART: RNA polymerase I subunit A domain protein YP_001214043.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001214044.1 PFAM: protein of unknown function DUF208 YP_001214045.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase YP_001214048.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001214049.1 TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001214050.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001214051.1 PFAM: nickel-dependent hydrogenase, large subunit YP_001214052.1 TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein YP_001214054.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001214055.1 PFAM: cytochrome c biogenesis protein, transmembrane region YP_001214058.1 PFAM: Radical SAM domain protein YP_001214059.1 TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit, N terminal domain protein YP_001214060.1 TIGRFAM: metal dependent phophohydrolase; PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; HDOD; SMART: metal-dependent phosphohydrolase, HD region YP_001214061.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001214062.1 PFAM: protein of unknown function UPF0153 YP_001214064.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein YP_001214065.1 PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein YP_001214066.1 PFAM: ferric-uptake regulator YP_001214067.1 PFAM: periplasmic solute binding protein YP_001214068.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214069.1 PFAM: ABC-3 protein YP_001214071.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001214072.1 PFAM: cell division protein FtsA YP_001214075.1 PFAM: UspA domain protein YP_001214076.1 PFAM: cyclase family protein YP_001214077.1 PFAM: ribulose-phosphate 3-epimerase YP_001214078.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001214079.1 TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region YP_001214080.1 PFAM: nitroreductase YP_001214081.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001214083.1 PFAM: periplasmic binding protein YP_001214084.1 PFAM: transport system permease protein; ABC-3 protein YP_001214085.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214086.1 PFAM: protein of unknown function DUF105 YP_001214087.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB YP_001214088.1 PFAM: aminotransferase, class I and II YP_001214089.1 PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase YP_001214090.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS YP_001214091.1 PFAM: Phosphoglycerate mutase YP_001214092.1 PFAM: cobalbumin biosynthesis enzyme YP_001214093.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001214094.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001214095.1 PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein YP_001214097.1 part of a complex that catalyzes the cleavage of acetyl-CoA YP_001214098.1 in acetogenic organisms, this enzyme complex converts carbon dioxide to acetyl-CoA while in methanogenic organisms this enzyme is used to degrade acetyl-CoA to form methane and carbon dioxide; part of an enzyme complex YP_001214099.1 part of a complex that catalyzes the cleavage of acetyl-CoA YP_001214100.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001214102.1 PFAM: ferredoxin YP_001214103.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001214106.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001214107.1 TIGRFAM: trigger factor; PFAM: peptidylprolyl isomerase, FKBP-type; trigger factor, C-terminal domain protein; trigger factor, N-terminal domain YP_001214108.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001214109.1 PFAM: PfkB domain protein YP_001214111.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001214112.1 TIGRFAM: translation elongation factor P; PFAM: Elongation factor P/YeiP protein; Elongation factor, KOW domain protein YP_001214113.1 PFAM: creatinase; peptidase M24 YP_001214114.1 TIGRFAM: tyrosine recombinase XerC; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001214115.1 TIGRFAM: DNA topoisomerase I; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein YP_001214116.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein YP_001214118.1 PFAM: sodium/hydrogen exchanger YP_001214119.1 TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase YP_001214120.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214121.1 PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein YP_001214122.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding YP_001214123.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001214124.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001214125.1 PFAM: oxidoreductase, molybdopterin binding YP_001214126.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_001214127.1 TIGRFAM: putative regulatory protein, FmdB family YP_001214128.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001214129.1 PFAM: GTP-binding protein, HSR1-related YP_001214131.1 catalyzes the formation of LL-diaminopimelate from tetrahydrodipicolinate; involved in lysine and peptidoglycan synthesis YP_001214132.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001214133.1 TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase YP_001214134.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001214135.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM YP_001214136.1 PFAM: phosphoglycerate kinase YP_001214137.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001214138.1 PFAM: putative small multi-drug export YP_001214139.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; GAF domain protein YP_001214140.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001214141.1 PFAM: ribosomal protein L35 YP_001214142.1 PFAM: initiation factor 3 YP_001214143.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001214147.1 PFAM: alanine racemase domain protein YP_001214148.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); 2,3-diketo-5-methylthio-1-phosphopentane phosphatase YP_001214149.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001214152.1 PFAM: dienelactone hydrolase YP_001214154.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001214156.1 PFAM: protein of unknown function UPF0132 YP_001214157.1 PFAM: CBS domain containing protein; peptidase M50 YP_001214158.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein YP_001214159.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase YP_001214161.1 PFAM: Abortive infection protein YP_001214162.1 PFAM: peptidase M50 YP_001214163.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001214164.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001214165.1 PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: AAA ATPase YP_001214166.1 PFAM: thymidylate kinase YP_001214167.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001214168.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001214169.1 PFAM: protein of unknown function UPF0102 YP_001214170.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001214171.1 PFAM: Translin YP_001214172.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001214173.1 PFAM: beta-lactamase domain protein YP_001214175.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001214176.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase YP_001214177.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001214178.1 PFAM: phosphoribosyltransferase YP_001214179.1 TIGRFAM: adenine deaminase; PFAM: amidohydrolase YP_001214180.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001214182.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214183.1 PFAM: ABC-2 type transporter YP_001214184.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001214185.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001214187.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001214188.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001214189.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001214190.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001214191.1 PFAM: major facilitator superfamily MFS_1 YP_001214192.1 PFAM: transcriptional regulator PadR family protein YP_001214195.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214196.1 PFAM: ABC-2 type transporter YP_001214197.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214198.1 PFAM: SufBD protein YP_001214199.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214203.1 PFAM: protein of unknown function DUF101 YP_001214204.1 PFAM: protein of unknown function UPF0027 YP_001214205.1 PFAM: nitroreductase YP_001214206.1 TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain YP_001214207.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001214208.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_001214209.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_001214210.1 PFAM: MgtC/SapB transporter YP_001214211.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001214212.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001214213.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001214214.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001214215.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001214216.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001214217.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001214219.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001214220.1 TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase YP_001214221.1 TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase YP_001214222.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001214223.1 TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class V; aminotransferase, class I and II; Allinase-like YP_001214224.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001214225.1 PFAM: ATP phosphoribosyltransferase, catalytic region YP_001214226.1 PFAM: tRNA synthetase, class II (G, H, P and S) YP_001214228.1 PFAM: band 7 protein YP_001214229.1 TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase YP_001214231.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214235.1 PFAM: protein of unknown function DUF214 YP_001214236.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214237.1 TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001214238.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001214239.1 PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001214240.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001214241.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001214242.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001214243.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001214244.1 PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214245.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001214246.1 PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa YP_001214247.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214248.1 PFAM: tRNA synthetase, class II (G, H, P and S); tRNA synthetase, class II (D, K and N) YP_001214249.1 TIGRFAM: translation elongation factor P; PFAM: Elongation factor P/YeiP protein; Elongation factor, KOW domain protein YP_001214250.1 PFAM: regulatory protein, MarR YP_001214251.1 PFAM: MMPL domain protein YP_001214252.1 PFAM: helix-turn-helix domain protein YP_001214253.1 PFAM: transcriptional regulator TrmB; Helix-turn-helix, type 11 domain protein YP_001214254.1 PFAM: Arsenical pump membrane protein; Citrate transporter YP_001214255.1 PFAM: major facilitator superfamily MFS_1 YP_001214256.1 PFAM: peptidase M29, aminopeptidase II YP_001214257.1 PFAM: phosphoribosyltransferase YP_001214258.1 PFAM: Rubrerythrin YP_001214261.1 PFAM: protein of unknown function DUF75 YP_001214264.1 PFAM: protein of unknown function DUF375 YP_001214265.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214266.1 PFAM: protein of unknown function DUF39 YP_001214267.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001214268.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_001214269.1 TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001214270.1 PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit YP_001214271.1 TIGRFAM: NADH dehydrogenase I, D subunit; PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa YP_001214272.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001214273.1 TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214274.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001214275.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001214276.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001214277.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001214278.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001214279.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001214280.1 TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001214281.1 TIGRFAM: cobyric acid synthase CobQ; PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase YP_001214282.1 PFAM: thioesterase superfamily protein YP_001214283.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214286.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214289.1 PFAM: inner-membrane translocator YP_001214290.1 PFAM: inner-membrane translocator YP_001214291.1 PFAM: AMP-dependent synthetase and ligase YP_001214292.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding YP_001214293.1 Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. YP_001214294.1 PFAM: CBS domain containing protein YP_001214296.1 PFAM: nitrogen-fixing NifU domain protein YP_001214298.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001214299.1 PFAM: heat shock protein Hsp20 YP_001214300.1 PFAM: Rubrerythrin; Ferritin, Dps family protein YP_001214301.1 PFAM: manganese and iron superoxide dismutase YP_001214306.1 PFAM: phage integrase family protein YP_001214307.1 TIGRFAM: reductive dehalogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214308.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001214309.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001214310.1 PFAM: Smr protein/MutS2 YP_001214311.1 PFAM: histidine biosynthesis protein YP_001214312.1 PFAM: Protein of unknown function DUF128; Ribonuclease R winged-helix domain protein YP_001214313.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB YP_001214314.1 PFAM: beta-ketoacyl synthase YP_001214315.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1 YP_001214316.1 PFAM: protein of unknown function DUF205 YP_001214317.1 PFAM: prolipoprotein diacylglyceryl transferase YP_001214318.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001214319.1 PFAM: protein of unknown function DUF503 YP_001214320.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001214321.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001214322.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001214323.1 TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_001214324.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001214326.1 PFAM: GCN5-related N-acetyltransferase YP_001214327.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001214328.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001214329.1 PFAM: glycosyl transferase, group 1 YP_001214330.1 PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH domain protein YP_001214332.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001214333.1 PFAM: ribosome-binding factor A YP_001214334.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001214335.1 PFAM: protein of unknown function DUF448 YP_001214336.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001214337.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase YP_001214338.1 PFAM: GCN5-related N-acetyltransferase YP_001214339.1 PFAM: GCN5-related N-acetyltransferase YP_001214340.1 PFAM: protein of unknown function DUF502 YP_001214341.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001214342.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001214343.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001214344.1 binds directly to 23S ribosomal RNA YP_001214345.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_001214346.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001214347.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_001214348.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001214349.1 PFAM: LmbE family protein YP_001214350.1 PFAM: glycosyl transferase, group 1 YP_001214352.1 PFAM: regulatory protein, ArsR YP_001214353.1 PFAM: permease YP_001214354.1 TIGRFAM: redox-active disulfide protein 2 YP_001214356.1 PFAM: major facilitator superfamily MFS_1 YP_001214363.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001214368.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein YP_001214370.1 catalyzes the hydrolysis of acylphosphate YP_001214373.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein YP_001214375.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001214376.1 PFAM: AMP-dependent synthetase and ligase YP_001214377.1 catalyzes the formation of L-tryptophan from indole and L-serine YP_001214378.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001214379.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001214380.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_001214381.1 PFAM: single-stranded nucleic acid binding R3H domain protein YP_001214382.1 PFAM: Pyrrolo-quinoline quinone YP_001214383.1 TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein YP_001214384.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001214385.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001214386.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n YP_001214387.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001214389.1 PFAM: Endoribonuclease L-PSP YP_001214391.1 PFAM: Tubulin/FtsZ, GTPase YP_001214392.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein YP_001214393.1 PFAM: protein of unknown function DUF6, transmembrane YP_001214395.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001214396.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001214397.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001214398.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001214399.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001214400.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001214401.1 PFAM: extracellular solute-binding protein, family 5 YP_001214402.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001214403.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001214404.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001214405.1 PFAM: (Uracil-5)-methyltransferase YP_001214407.1 TIGRFAM: maf protein; PFAM: Maf family protein YP_001214409.1 TIGRFAM: NAD+ synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; NAD+ synthase YP_001214410.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_001214411.1 PFAM: nitrogen regulatory protein P-II YP_001214412.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter YP_001214413.1 PFAM: transcriptional regulator domain protein YP_001214414.1 PFAM: glutamate synthase, alpha subunit domain protein YP_001214415.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; ferredoxin-dependent glutamate synthase YP_001214416.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001214417.1 PFAM: glutamine amidotransferase, class-II YP_001214418.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001214419.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001214420.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214421.1 PFAM: protein of unknown function DUF204 YP_001214422.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001214424.1 PFAM: Radical SAM domain protein YP_001214425.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB YP_001214426.1 PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_001214427.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001214428.1 PFAM: glycosyl transferase, family 2; polysaccharide deacetylase YP_001214432.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001214433.1 PFAM: GCN5-related N-acetyltransferase YP_001214434.1 PFAM: transposase IS3/IS911 family protein YP_001214435.1 PFAM: Integrase, catalytic region YP_001214436.1 PFAM: CoA-binding domain protein YP_001214437.1 PFAM: Ig domain protein, group 1 domain protein YP_001214438.1 PFAM: ferric-uptake regulator YP_001214439.1 PFAM: alpha/beta hydrolase fold YP_001214440.1 PFAM: transcriptional regulator PadR family protein YP_001214441.1 PFAM: regulatory protein, MarR YP_001214442.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001214443.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001214444.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214445.1 PFAM: regulatory protein, MarR YP_001214446.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214448.1 TIGRFAM: putative regulatory protein, FmdB family YP_001214451.1 PFAM: protein of unknown function DUF105 YP_001214453.1 PFAM: BioY protein YP_001214456.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001214457.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II YP_001214458.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001214459.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001214460.1 PFAM: protein of unknown function DUF541 YP_001214461.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001214462.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001214464.1 TIGRFAM: DNA mismatch repair protein MutL; PFAM: DNA mismatch repair protein, C-terminal domain protein YP_001214465.1 PFAM: UvrD/REP helicase YP_001214466.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001214467.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001214468.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001214469.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001214470.1 TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein YP_001214471.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001214472.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001214473.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001214474.1 PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding YP_001214476.1 PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001214477.1 TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase YP_001214478.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001214479.1 TIGRFAM: modification methylase, HemK family; PFAM: putative RNA methylase; methyltransferase small YP_001214480.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001214481.1 PFAM: protein of unknown function DUF95, transmembrane YP_001214483.1 TIGRFAM: tyrosine recombinase XerD; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001214484.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001214485.1 PFAM: GCN5-related N-acetyltransferase YP_001214486.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase, type 3 YP_001214487.1 This protein performs the mismatch recognition step during the DNA repair process YP_001214490.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001214491.1 PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_001214492.1 PFAM: protein of unknown function DUF100 YP_001214493.1 TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein YP_001214494.1 TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_001214495.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001214497.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system YP_001214501.1 PFAM: DNA methylase N-4/N-6 domain protein YP_001214502.1 PFAM: type III restriction enzyme, res subunit YP_001214508.1 PFAM: alpha/beta hydrolase fold YP_001214509.1 PFAM: Smr protein/MutS2 YP_001214510.1 TIGRFAM: formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein; amino acid-binding ACT domain protein YP_001214511.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001214512.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter YP_001214513.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001214514.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; a fusion protein of this enzyme with MsrA and thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001214515.1 PFAM: NADPH-dependent FMN reductase YP_001214516.1 PFAM: TfoX, N-terminal domain protein YP_001214518.1 PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein YP_001214519.1 PFAM: protein of unknown function DUF1648 YP_001214521.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase YP_001214524.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001214525.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001214526.1 TIGRFAM: acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase YP_001214527.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001214529.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001214530.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001214531.1 required for 70S ribosome assembly YP_001214532.1 PFAM: Dak phosphatase YP_001214533.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001214534.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001214535.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001214536.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001214537.1 catalyzes branch migration in Holliday junction intermediates YP_001214538.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001214539.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001214540.1 PFAM: regulatory protein, AsnC/Lrp family YP_001214544.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001214545.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein YP_001214546.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001214547.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44 YP_001214548.1 carries the fatty acid chain in fatty acid biosynthesis YP_001214549.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001214550.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001214551.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001214554.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001214555.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001214556.1 PFAM: regulatory protein, MerR; TipAS antibiotic-recognition domain protein YP_001214557.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001214558.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001214559.1 PFAM: NUDIX hydrolase YP_001214560.1 PFAM: CinA domain protein YP_001214561.1 PFAM: protein of unknown function DUF167 YP_001214562.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001214564.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: response regulator receiver; Prophage CP4-57 regulatory YP_001214567.1 TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001214568.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001214569.1 PFAM: UspA domain protein YP_001214570.1 PFAM: beta-Ig-H3/fasciclin YP_001214574.1 PFAM: protein of unknown function DUF1508 YP_001214575.1 PFAM: alpha/beta hydrolase fold YP_001214576.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001214579.1 PFAM: AMMECR1 domain protein; protein of unknown function DUF52 YP_001214580.1 PFAM: Radical SAM domain protein YP_001214581.1 PFAM: protein of unknown function DUF6, transmembrane YP_001214583.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001214586.1 SMART: AAA ATPase YP_001214587.1 PFAM: NADPH-dependent FMN reductase YP_001214588.1 PFAM: GCN5-related N-acetyltransferase YP_001214591.1 TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase YP_001214592.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001214593.1 PFAM: ribosomal protein L21 YP_001214594.1 involved in the peptidyltransferase reaction during translation YP_001214595.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001214596.1 PFAM: protein of unknown function DUF1385 YP_001214597.1 PFAM: phosphoribosyl-AMP cyclohydrolase YP_001214598.1 PFAM: GCN5-related N-acetyltransferase YP_001214599.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001214601.1 PFAM: protein of unknown function DUF107 YP_001214602.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase, C subunit YP_001214603.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001214606.1 PFAM: helix-turn-helix domain protein YP_001214607.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214608.1 PFAM: ABC-2 type transporter YP_001214609.1 PFAM: regulatory protein, AsnC/Lrp family YP_001214610.1 PFAM: aminotransferase, class I and II YP_001214611.1 TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib YP_001214612.1 TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein YP_001214613.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources YP_001214614.1 PFAM: PfkB domain protein YP_001214616.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001214618.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein, MerR YP_001214619.1 PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein YP_001214620.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein YP_001214621.1 PFAM: type II secretion system protein YP_001214628.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001214630.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein YP_001214631.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; functions in mannosylglycerate biosynthesis YP_001214632.1 PFAM: RDD domain containing protein YP_001214633.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001214636.1 PFAM: Radical SAM domain protein YP_001214638.1 PFAM: protein of unknown function UPF0054 YP_001214639.1 PFAM: NADPH-dependent FMN reductase YP_001214640.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_001214641.1 PFAM: zinc finger, DksA/TraR C4-type YP_001214642.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001214643.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001214647.1 PFAM: GH3 auxin-responsive promoter YP_001214648.1 TIGRFAM: diguanylate cyclase; metal dependent phophohydrolase; PFAM: GGDEF domain containing protein; GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001214649.1 TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001214650.1 TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001214651.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein YP_001214652.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001214654.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001214655.1 TIGRFAM: formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase YP_001214656.1 PFAM: phosphoesterase, PA-phosphatase related YP_001214657.1 TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001214658.1 PFAM: Rhodanese domain protein YP_001214660.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001214661.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001214662.1 PFAM: protein of unknown function DUF205 YP_001214663.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001214664.1 TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein YP_001214665.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001214666.1 PFAM: GrpE protein YP_001214667.1 TIGRFAM: heat-inducible transcription repressor HrcA; PFAM: Negative regulator of class I heat shock protein YP_001214672.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001214673.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_001214674.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001214675.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein YP_001214676.1 PFAM: regulatory protein, MerR YP_001214677.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001214679.1 TIGRFAM: amidophosphoribosyltransferase; PFAM: glutamine amidotransferase, class-II; phosphoribosyltransferase YP_001214680.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001214681.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001214682.1 involved in de novo purine biosynthesis YP_001214683.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001214684.1 TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein YP_001214685.1 in Rhodopseudomonas palustris this protein confers resistance to arsenite; catalyzes the formation of a number of methylated intermediates from arsenite and SAM producing trimethylarsine YP_001214686.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein YP_001214687.1 PFAM: Phosphoglycerate mutase YP_001214688.1 PFAM: peptidase M48, Ste24p YP_001214690.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001214691.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001214692.1 PFAM: chaperonin Cpn10 YP_001214693.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001214694.1 PFAM: peptidase M16 domain protein YP_001214695.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis, HypA YP_001214696.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K YP_001214697.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein YP_001214698.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC) YP_001214699.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein YP_001214700.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001214701.1 PFAM: regulatory protein, TetR YP_001214706.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein, MerR YP_001214708.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001214709.1 PFAM: cyclase/dehydrase; Activator of Hsp90 ATPase 1 family protein YP_001214712.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001214713.1 PFAM: amidohydrolase 2 YP_001214714.1 TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase YP_001214717.1 TIGRFAM: ribosomal subunit interface protein YP_001214718.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001214720.1 PFAM: DNA repair protein RadC YP_001214722.1 TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein YP_001214723.1 TIGRFAM: integral membrane protein TIGR01906; PFAM: Integral membrane protein 1906 YP_001214726.1 TIGRFAM: putative regulatory protein, FmdB family YP_001214728.1 TIGRFAM: anthranilate synthase component I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein YP_001214729.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001214730.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001214731.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001214732.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI) YP_001214733.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001214734.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001214735.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001214736.1 TIGRFAM: thymidylate synthase, flavin-dependent; PFAM: thymidylate synthase complementing protein ThyX YP_001214737.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001214738.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001214739.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001214740.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001214741.1 PFAM: extracellular solute-binding protein, family 5 YP_001214742.1 PFAM: Methyltransferase type 12 YP_001214743.1 PFAM: regulatory protein, MarR YP_001214745.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001214746.1 PFAM: Helix-turn-helix, type 11 domain protein YP_001214748.1 PFAM: flavodoxin/nitric oxide synthase YP_001214749.1 PFAM: major facilitator superfamily MFS_1 YP_001214750.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport B domain protein; nucleoside recognition domain protein YP_001214751.1 PFAM: FeoA family protein YP_001214752.1 PFAM: ferric-uptake regulator YP_001214753.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001214754.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001214755.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein YP_001214757.1 PFAM: transposase IS3/IS911 family protein YP_001214758.1 PFAM: Integrase, catalytic region YP_001214760.1 PFAM: prephenate dehydratase YP_001214761.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit YP_001214762.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001214765.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001214766.1 PFAM: regulatory protein, MerR YP_001214771.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001214772.1 PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; NADH dehydrogenase (ubiquinone), 30 kDa subunit YP_001214773.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001214776.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001214777.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001214778.1 TIGRFAM: putative regulatory protein, FmdB family YP_001214779.1 PFAM: MscS Mechanosensitive ion channel YP_001214780.1 PFAM: Integrase, catalytic region YP_001214781.1 PFAM: transposase IS3/IS911 family protein YP_001214782.1 PFAM: regulatory protein, TetR YP_001214783.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001214784.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001214785.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001214789.1 PFAM: LemA family protein YP_001214790.1 PFAM: peptidase M48, Ste24p YP_001214791.1 TIGRFAM: serine O-acetyltransferase YP_001214792.1 PFAM: CutA1 divalent ion tolerance protein YP_001214793.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001214794.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001214795.1 PFAM: AIR synthase related protein domain protein YP_001214796.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001214797.1 PFAM: ApbE family lipoprotein YP_001214798.1 PFAM: FMN-binding domain protein YP_001214800.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase YP_001214801.1 PFAM: sec-independent translocation protein mttA/Hcf106 YP_001214802.1 PFAM: sec-independent translocation protein mttA/Hcf106 YP_001214803.1 PFAM: sec-independent translocation protein mttA/Hcf106 YP_001214804.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001214805.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001214806.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001214807.1 TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: AAA ATPase YP_001214808.1 PFAM: regulatory protein RecX YP_001214809.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_001214810.1 PFAM: metallophosphoesterase YP_001214811.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001214812.1 PFAM: protein of unknown function DUF205 YP_001214813.1 PFAM: HhH-GPD family protein YP_001214814.1 PFAM: protein of unknown function UPF0066 YP_001214815.1 PFAM: pyruvate carboxyltransferase YP_001214816.1 PFAM: histidine triad (HIT) protein YP_001214818.1 PFAM: protein of unknown function DUF74 YP_001214820.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001214822.1 TIGRFAM: cell wall/surface repeat protein YP_001214824.1 PFAM: Desulfoferrodoxin Dfx domain protein YP_001214826.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001214827.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger YP_001214828.1 PFAM: beta-lactamase domain protein YP_001214829.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001214830.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller YP_001214831.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001214832.1 PFAM: nitrogen-fixing NifU domain protein YP_001214833.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001214835.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM YP_001214836.1 TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase YP_001214837.1 PFAM: peptidase, membrane zinc metallopeptidase, putative YP_001214838.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001214839.1 TIGRFAM: LexA repressor; PFAM: peptidase S24, S26A and S26B; LexA DNA-binding domain protein YP_001214840.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_001214841.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein