-- dump date 20140619_053701 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 290339000001 SEQ_END SEQ_END NC_009778.1 4368373 4368373 DR NC_009778.1; contig end 4368373..4368373 Cronobacter sakazakii ATCC BAA-894 290339000002 SEQ_END SEQ_END NC_009779.1 31208 31208 DR NC_009779.1; contig end 31208..31208 Cronobacter sakazakii ATCC BAA-894 290339000003 SEQ_END SEQ_END NC_009780.1 131196 131196 DR NC_009780.1; contig end 131196..131196 Cronobacter sakazakii ATCC BAA-894 YP_001436146.1 CDS ESA_00001 NC_009778.1 340 651 D COG: COG0051 Ribosomal protein S10; Psort location: cytoplasmic, score: 23; hypothetical protein 340..651 Cronobacter sakazakii ATCC BAA-894 5549280 YP_001436147.1 CDS rplC NC_009778.1 684 1313 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 684..1313 Cronobacter sakazakii ATCC BAA-894 5548631 YP_001436148.1 CDS ESA_00003 NC_009778.1 693 1085 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(693..1085) Cronobacter sakazakii ATCC BAA-894 5548605 YP_001436149.1 CDS rplD NC_009778.1 1324 1929 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1324..1929 Cronobacter sakazakii ATCC BAA-894 5548703 YP_001436151.1 CDS rplW NC_009778.1 1926 2228 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1926..2228 Cronobacter sakazakii ATCC BAA-894 5552259 YP_001436153.1 CDS rplB NC_009778.1 2300 3067 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2300..3067 Cronobacter sakazakii ATCC BAA-894 5548832 YP_001436154.1 CDS rpsS NC_009778.1 3084 3362 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3084..3362 Cronobacter sakazakii ATCC BAA-894 5548732 YP_001436155.1 CDS rplV NC_009778.1 3376 3708 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3376..3708 Cronobacter sakazakii ATCC BAA-894 5548826 YP_001436156.1 CDS rpsC NC_009778.1 3726 4427 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3726..4427 Cronobacter sakazakii ATCC BAA-894 5548840 YP_001436157.1 CDS ESA_00012 NC_009778.1 4682 4849 D COG: COG0197 Ribosomal protein L16/L10E; Psort location: cytoplasmic, score: 23; hypothetical protein 4682..4849 Cronobacter sakazakii ATCC BAA-894 5548765 YP_001436158.1 CDS ESA_00013 NC_009778.1 4849 5040 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 4849..5040 Cronobacter sakazakii ATCC BAA-894 5548664 YP_001436159.1 CDS rpsQ NC_009778.1 5040 5294 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 5040..5294 Cronobacter sakazakii ATCC BAA-894 5552384 YP_001436161.1 CDS rplN NC_009778.1 5460 5831 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 5460..5831 Cronobacter sakazakii ATCC BAA-894 5548894 YP_001436162.1 CDS rplX NC_009778.1 5842 6156 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 5842..6156 Cronobacter sakazakii ATCC BAA-894 5548951 YP_001436163.1 CDS rplE NC_009778.1 6171 6710 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 6171..6710 Cronobacter sakazakii ATCC BAA-894 5548992 YP_001436164.1 CDS rpsN NC_009778.1 6725 7030 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 6725..7030 Cronobacter sakazakii ATCC BAA-894 5548877 YP_001436166.1 CDS rpsH NC_009778.1 7064 7456 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 7064..7456 Cronobacter sakazakii ATCC BAA-894 5548844 YP_001436167.1 CDS rplF NC_009778.1 7469 8002 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 7469..8002 Cronobacter sakazakii ATCC BAA-894 5548964 YP_001436168.1 CDS rplR NC_009778.1 8012 8365 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 8012..8365 Cronobacter sakazakii ATCC BAA-894 5548697 YP_001436169.1 CDS rpsE NC_009778.1 8380 8880 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 8380..8880 Cronobacter sakazakii ATCC BAA-894 5548974 YP_001436170.1 CDS rpmD NC_009778.1 8887 9066 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 8887..9066 Cronobacter sakazakii ATCC BAA-894 5549000 YP_001436171.1 CDS ESA_00026 NC_009778.1 9283 9504 D COG: COG0200 Ribosomal protein L15; Psort location: cytoplasmic, score: 23; 50S ribosomal protein L15 9283..9504 Cronobacter sakazakii ATCC BAA-894 5552172 YP_001436172.1 CDS secY NC_009778.1 9512 10843 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 9512..10843 Cronobacter sakazakii ATCC BAA-894 5548899 YP_001436173.1 CDS rpmJ NC_009778.1 10874 10990 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 10874..10990 Cronobacter sakazakii ATCC BAA-894 5548896 YP_001436174.1 CDS rpsM NC_009778.1 11137 11493 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 11137..11493 Cronobacter sakazakii ATCC BAA-894 5548890 YP_004770510.1 CDS ESA_p1 NC_009778.1 11510 11899 D ribosomal protein S11 11510..11899 Cronobacter sakazakii ATCC BAA-894 11030701 YP_001436175.1 CDS rpsD NC_009778.1 11931 12551 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 11931..12551 Cronobacter sakazakii ATCC BAA-894 5548827 YP_001436176.1 CDS ESA_00031 NC_009778.1 12577 13566 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 12577..13566 Cronobacter sakazakii ATCC BAA-894 5548823 YP_001436177.1 CDS ESA_00032 NC_009778.1 13664 13993 D COG: COG0203 Ribosomal protein L17; Psort location: cytoplasmic, score: 23; hypothetical protein 13664..13993 Cronobacter sakazakii ATCC BAA-894 5552343 YP_001436178.1 CDS ESA_00033 NC_009778.1 14042 14479 D COG: NOG18395 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 14042..14479 Cronobacter sakazakii ATCC BAA-894 5548864 YP_001436179.1 CDS zntR NC_009778.1 14479 14904 D mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 14479..14904 Cronobacter sakazakii ATCC BAA-894 5548857 YP_001436180.1 CDS mscL NC_009778.1 15172 15579 R forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel complement(15172..15579) Cronobacter sakazakii ATCC BAA-894 5548842 YP_001436181.1 CDS trkA NC_009778.1 15734 17110 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component complement(15734..17110) Cronobacter sakazakii ATCC BAA-894 5548988 YP_001436182.1 CDS ESA_00037 NC_009778.1 17150 18439 R catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B complement(17150..18439) Cronobacter sakazakii ATCC BAA-894 5548882 YP_001436183.1 CDS ESA_00038 NC_009778.1 18508 19455 R KEGG: sdy:SDY_3464 1.4e-134 fmt; 10-formyltetrahydrofolate:L-meTHIonyl-tRNA(fMet) N-formyltransferase K00604; COG: COG0223 MeTHIonyl-tRNA formyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(18508..19455) Cronobacter sakazakii ATCC BAA-894 5548819 YP_001436184.1 CDS def NC_009778.1 19474 19989 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(19474..19989) Cronobacter sakazakii ATCC BAA-894 5548846 YP_001436185.1 CDS ESA_00040 NC_009778.1 20119 21231 D COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: cytoplasmic, score: 23; DNA protecting protein DprA 20119..21231 Cronobacter sakazakii ATCC BAA-894 5548502 YP_001436186.1 CDS ESA_00041 NC_009778.1 21218 21676 D COG: COG2922 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 21218..21676 Cronobacter sakazakii ATCC BAA-894 5548497 YP_001436187.1 CDS ESA_00042 NC_009778.1 21700 22257 D KEGG: mca:MCA2839 2.3e-43 topA; DNA topoisomerase I K03168; COG: COG0551 Zn-finger domain associated with topoisomerase type I; Psort location: nuclear, score: 23; hypothetical protein 21700..22257 Cronobacter sakazakii ATCC BAA-894 5548807 YP_001436188.1 CDS ESA_00043 NC_009778.1 22247 22819 D RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor 22247..22819 Cronobacter sakazakii ATCC BAA-894 5548809 YP_001436189.1 CDS aroE NC_009778.1 22823 23641 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 22823..23641 Cronobacter sakazakii ATCC BAA-894 5550898 YP_001436190.1 CDS ESA_00045 NC_009778.1 23638 23895 D COG: NOG13911 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 23638..23895 Cronobacter sakazakii ATCC BAA-894 5548498 YP_001436191.1 CDS ESA_00046 NC_009778.1 23871 24368 R KEGG: eci:UTI89_C3724 4.2e-78 yrdA; protein YrdA K00680; COG: COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein complement(23871..24368) Cronobacter sakazakii ATCC BAA-894 5551018 YP_001436193.1 CDS ESA_00052 NC_009778.1 30419 31348 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 30419..31348 Cronobacter sakazakii ATCC BAA-894 5551274 YP_001436194.1 CDS ESA_00053 NC_009778.1 31621 33219 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 31621..33219 Cronobacter sakazakii ATCC BAA-894 5551154 YP_001436195.1 CDS ESA_00054 NC_009778.1 33259 34566 D KEGG: sdy:SDY_4328 6.8e-220 aceA; isocitrate lyase K01637; COG: COG2224 Isocitrate lyase; Psort location: cytoplasmic, score: 23; hypothetical protein 33259..34566 Cronobacter sakazakii ATCC BAA-894 5548966 YP_001436196.1 CDS aceK NC_009778.1 34828 36618 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 34828..36618 Cronobacter sakazakii ATCC BAA-894 5548932 YP_001436197.1 CDS ESA_00056 NC_009778.1 36662 37501 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR complement(36662..37501) Cronobacter sakazakii ATCC BAA-894 5551119 YP_001436198.1 CDS ESA_00057 NC_009778.1 37523 37702 D Psort location: cytoplasmic, score: 23; hypothetical protein 37523..37702 Cronobacter sakazakii ATCC BAA-894 5548687 YP_001436199.1 CDS metH NC_009778.1 37747 41382 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 37747..41382 Cronobacter sakazakii ATCC BAA-894 5548916 YP_001436200.1 CDS ESA_00059 NC_009778.1 41874 43505 D COG: COG1283 Na+/phosphate symporter; Psort location: plasma membrane, score: 23; hypothetical protein 41874..43505 Cronobacter sakazakii ATCC BAA-894 5548914 YP_001436201.1 CDS ESA_00060 NC_009778.1 43656 43928 R COG: NOG14139 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(43656..43928) Cronobacter sakazakii ATCC BAA-894 5548934 YP_001436202.1 CDS ESA_00061 NC_009778.1 44019 45095 R KEGG: nfa:nfa24500 0.0025 putative arsenite transporter K03741:K03325; COG: COG0385 Predicted Na+-dependent transporter; Psort location: plasma membrane, score: 23; hypothetical protein complement(44019..45095) Cronobacter sakazakii ATCC BAA-894 5548931 YP_001436203.1 CDS ESA_00062 NC_009778.1 45117 46709 R KEGG: eci:UTI89_C2502 5.4e-37 atoC; acetoacetate metabolism regulatory protein AtoC K07714; COG: COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(45117..46709) Cronobacter sakazakii ATCC BAA-894 5548933 YP_001436204.1 CDS ESA_00063 NC_009778.1 46816 47070 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(46816..47070) Cronobacter sakazakii ATCC BAA-894 5548978 YP_001436205.1 CDS ESA_00064 NC_009778.1 47185 48318 D KEGG: reh:H16_A2768 1.7e-16 predicted membrane-bound protease subunit K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs; Psort location: cytoplasmic, score: 23; hypothetical protein 47185..48318 Cronobacter sakazakii ATCC BAA-894 5548652 YP_001436206.1 CDS ESA_00065 NC_009778.1 48321 49547 D COG: COG1690 Uncharacterized conserved protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 48321..49547 Cronobacter sakazakii ATCC BAA-894 5548965 YP_001436207.1 CDS ESA_00066 NC_009778.1 49561 50349 D COG: COG3541 Predicted nucleotidyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 49561..50349 Cronobacter sakazakii ATCC BAA-894 5548983 YP_001436208.1 CDS ESA_00067 NC_009778.1 50373 51725 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(50373..51725) Cronobacter sakazakii ATCC BAA-894 5548980 YP_001436209.1 CDS ESA_00068 NC_009778.1 52288 52464 D Psort location: cytoplasmic, score: 23; hypothetical protein 52288..52464 Cronobacter sakazakii ATCC BAA-894 5552193 YP_001436210.1 CDS pgi NC_009778.1 52461 54110 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 52461..54110 Cronobacter sakazakii ATCC BAA-894 5548939 YP_001436211.1 CDS ESA_00071 NC_009778.1 54126 54254 R Psort location: mitochondrial, score: 23; hypothetical protein complement(54126..54254) Cronobacter sakazakii ATCC BAA-894 5548408 YP_001436212.1 CDS ESA_00070 NC_009778.1 54181 54315 D Psort location: cytoskeletal, score: 9; hypothetical protein 54181..54315 Cronobacter sakazakii ATCC BAA-894 5548977 YP_001436214.1 CDS ESA_00072 NC_009778.1 54492 54740 D COG: NOG14141 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 54492..54740 Cronobacter sakazakii ATCC BAA-894 5548981 YP_001436215.1 CDS ESA_00074 NC_009778.1 54833 55444 D COG: NOG06220 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 54833..55444 Cronobacter sakazakii ATCC BAA-894 5548971 YP_001436216.1 CDS ESA_00075 NC_009778.1 55444 56178 D COG: NOG06780 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 55444..56178 Cronobacter sakazakii ATCC BAA-894 5548953 YP_001436217.1 CDS ESA_00076 NC_009778.1 56178 58274 D COG: NOG06257 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 56178..58274 Cronobacter sakazakii ATCC BAA-894 5552158 YP_001436218.1 CDS ESA_00077 NC_009778.1 58524 58991 R KEGG: mpe:MYPE1700 1.4e-13 nodL; acetyl transferase K00680; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein complement(58524..58991) Cronobacter sakazakii ATCC BAA-894 5552276 YP_001436219.1 CDS ESA_00078 NC_009778.1 58991 59632 R KEGG: ngo:NGO0916 0.0034 dihydrolipoamide acetyltransferase K00658; COG: NOG12520 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(58991..59632) Cronobacter sakazakii ATCC BAA-894 5552467 YP_001436220.1 CDS malG NC_009778.1 59840 60730 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(59840..60730) Cronobacter sakazakii ATCC BAA-894 5548581 YP_001436221.1 CDS malF NC_009778.1 60742 62286 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(60742..62286) Cronobacter sakazakii ATCC BAA-894 5552031 YP_001436222.1 CDS malE NC_009778.1 62552 63877 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(62552..63877) Cronobacter sakazakii ATCC BAA-894 5551551 YP_001436223.1 CDS ESA_00082 NC_009778.1 64112 65221 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 64112..65221 Cronobacter sakazakii ATCC BAA-894 5551171 YP_001436224.1 CDS lamB NC_009778.1 65247 66611 D porin involved in the transport of maltose and maltodextrins; maltoporin 65247..66611 Cronobacter sakazakii ATCC BAA-894 5552362 YP_001436225.1 CDS ESA_00084 NC_009778.1 66735 67676 D KEGG: sco:SCO2181 0.00095 SC5F7.20, sucB; putative dihydrolipoamide succinyltransferase K00658; COG: NOG06298 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; maltose regulon periplasmic protein 66735..67676 Cronobacter sakazakii ATCC BAA-894 5548655 YP_001436226.1 CDS ubiC NC_009778.1 67859 68368 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 67859..68368 Cronobacter sakazakii ATCC BAA-894 5548442 YP_001436227.1 CDS ubiA NC_009778.1 68368 69240 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 68368..69240 Cronobacter sakazakii ATCC BAA-894 5550975 YP_001436228.1 CDS ESA_00087 NC_009778.1 69522 71825 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(69522..71825) Cronobacter sakazakii ATCC BAA-894 5548709 YP_001436229.1 CDS ESA_00088 NC_009778.1 72081 72449 D KEGG: sfx:S3568 7.4e-49 dgkA; diacylglycerol kinase K00901; COG: COG0818 Diacylglycerol kinase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 72081..72449 Cronobacter sakazakii ATCC BAA-894 5548742 YP_001436230.1 CDS ESA_00089 NC_009778.1 72558 73166 D Represses a number of genes involved in the response to DNA damage; LexA repressor 72558..73166 Cronobacter sakazakii ATCC BAA-894 5552224 YP_001436231.1 CDS ESA_00090 NC_009778.1 73292 74599 D COG: COG0534 Na+-driven multidrug efflux pump; Psort location: plasma membrane, score: 23; DNA-damage-inducible SOS response protein 73292..74599 Cronobacter sakazakii ATCC BAA-894 5549065 YP_001436232.1 CDS ESA_00091 NC_009778.1 74807 75016 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 74807..75016 Cronobacter sakazakii ATCC BAA-894 5549496 YP_001436233.1 CDS ESA_00092 NC_009778.1 75096 75617 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(75096..75617) Cronobacter sakazakii ATCC BAA-894 5549044 YP_001436234.1 CDS ESA_00093 NC_009778.1 75721 76227 D COG: COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain; Psort location: cytoplasmic, score: 23; hypothetical protein 75721..76227 Cronobacter sakazakii ATCC BAA-894 5549063 YP_001436235.1 CDS ESA_00094 NC_009778.1 76427 77656 D COG: NOG11280 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 76427..77656 Cronobacter sakazakii ATCC BAA-894 5548956 YP_001436236.1 CDS ESA_00095 NC_009778.1 77801 78742 D KEGG: sec:SC4122 6.4e-153 yjbN; putative TIM-barrel enzymes, possibly dehydrogenases, nifR3 family K05539; COG: COG0042 tRNA-dihydrouridine synthase; Psort location: cytoplasmic, score: 23; tRNA-dihydrouridine synthase A 77801..78742 Cronobacter sakazakii ATCC BAA-894 5549006 YP_001436237.1 CDS ESA_00097 NC_009778.1 78803 79096 R Psort location: mitochondrial, score: 23; hypothetical protein complement(78803..79096) Cronobacter sakazakii ATCC BAA-894 5549203 YP_001436238.1 CDS pspG NC_009778.1 78873 79133 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 78873..79133 Cronobacter sakazakii ATCC BAA-894 5549036 YP_001436239.1 CDS ESA_00098 NC_009778.1 79314 80297 R KEGG: sty:STY4441 2.1e-145 qor; quinone oxidoreductase K00344; COG: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Psort location: cytoplasmic, score: 23; quinone oxidoreductase, NADPH-dependent complement(79314..80297) Cronobacter sakazakii ATCC BAA-894 5549076 YP_001436240.1 CDS ESA_00099 NC_009778.1 80418 81824 D unwinds double stranded DNA; replicative DNA helicase 80418..81824 Cronobacter sakazakii ATCC BAA-894 5549085 YP_001436241.1 CDS alr NC_009778.1 81985 83064 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 81985..83064 Cronobacter sakazakii ATCC BAA-894 5549102 YP_001436242.1 CDS ESA_00101 NC_009778.1 83473 84666 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 83473..84666 Cronobacter sakazakii ATCC BAA-894 5549043 YP_001436243.1 CDS ESA_00102 NC_009778.1 85087 86769 D COG: COG2831 Hemolysin activation/secretion protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 85087..86769 Cronobacter sakazakii ATCC BAA-894 5549061 YP_001436244.1 CDS ESA_00103 NC_009778.1 86880 87302 D COG: COG0432 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 86880..87302 Cronobacter sakazakii ATCC BAA-894 5549053 YP_001436245.1 CDS ESA_00104 NC_009778.1 87299 87652 D COG: COG2315 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 87299..87652 Cronobacter sakazakii ATCC BAA-894 5549008 YP_001436246.1 CDS ESA_00105 NC_009778.1 87694 88038 R COG: NOG29606 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(87694..88038) Cronobacter sakazakii ATCC BAA-894 5549054 YP_001436247.1 CDS ESA_00106 NC_009778.1 88051 88593 R COG: NOG26992 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(88051..88593) Cronobacter sakazakii ATCC BAA-894 5552412 YP_001436248.1 CDS uvrA NC_009778.1 88651 91476 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(88651..91476) Cronobacter sakazakii ATCC BAA-894 5549005 YP_001436249.1 CDS ESA_00108 NC_009778.1 91686 92243 D KEGG: shn:Shewana3_3590 1.4e-52 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein; Psort location: cytoplasmic, score: 23; hypothetical protein 91686..92243 Cronobacter sakazakii ATCC BAA-894 5549031 YP_001436250.1 CDS ESA_00109 NC_009778.1 92591 93637 D KEGG: bpm:BURPS1710b_A1493 1.4e-23 GGDEF domain protein; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 92591..93637 Cronobacter sakazakii ATCC BAA-894 5551919 YP_001436251.1 CDS ESA_00110 NC_009778.1 93804 94157 D COG: NOG14219 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 93804..94157 Cronobacter sakazakii ATCC BAA-894 5549116 YP_001436252.1 CDS ESA_00111 NC_009778.1 94219 94587 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(94219..94587) Cronobacter sakazakii ATCC BAA-894 5549041 YP_001436253.1 CDS ESA_00112 NC_009778.1 94617 94775 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(94617..94775) Cronobacter sakazakii ATCC BAA-894 5552178 YP_001436254.1 CDS ESA_00113 NC_009778.1 95083 96690 D KEGG: shn:Shewana3_3829 9.0e-34 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG4943 Predicted signal transduction protein containing sensor and EAL domains; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 95083..96690 Cronobacter sakazakii ATCC BAA-894 5552389 YP_001436255.1 CDS ESA_00114 NC_009778.1 96678 97001 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(96678..97001) Cronobacter sakazakii ATCC BAA-894 5549050 YP_001436256.1 CDS ESA_00115 NC_009778.1 97088 97546 D KEGG: eci:UTI89_C3737 9.9e-06 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 97088..97546 Cronobacter sakazakii ATCC BAA-894 5549093 YP_001436257.1 CDS ESA_00116 NC_009778.1 97624 98292 D KEGG: xac:XAC2394 2.4e-59 gstA; glutathione S-transferase K00799; COG: COG0625 glutathione S-transferase; Psort location: cytoplasmic, score: 23; hypothetical protein 97624..98292 Cronobacter sakazakii ATCC BAA-894 5549149 YP_001436258.1 CDS ESA_00117 NC_009778.1 98606 99955 D KEGG: bcz:BCZK0244 9.7e-63 guanine-hypoxanTHIne permease; xanTHIne/uracil permease family protein K06901; COG: COG2252 Permeases; Psort location: plasma membrane, score: 23; hypothetical protein 98606..99955 Cronobacter sakazakii ATCC BAA-894 5549032 YP_001436259.1 CDS ESA_00118 NC_009778.1 100095 101741 D COG: COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; Psort location: plasma membrane, score: 23; hypothetical protein 100095..101741 Cronobacter sakazakii ATCC BAA-894 5549209 YP_001436260.1 CDS ESA_00119 NC_009778.1 101774 103075 R KEGG: ret:RHE_CH03170 6.7e-14 idhA; myo-inositol 2-dehydrogenase protein K00010; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(101774..103075) Cronobacter sakazakii ATCC BAA-894 5549208 YP_001436261.1 CDS ESA_00120 NC_009778.1 103218 104864 R KEGG: rpr:RP465 1.2e-10 phoR; alkaline phosphatase synthesis sensor protein phoR K07636; COG: COG4147 Predicted symporter; Psort location: plasma membrane, score: 23; hypothetical protein complement(103218..104864) Cronobacter sakazakii ATCC BAA-894 5549098 YP_001436262.1 CDS ESA_00121 NC_009778.1 104861 105178 R KEGG: rba:RB12291 0.0092 probable NAD(P) transhydrogenase subunit alpha K00324; COG: COG3162 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(104861..105178) Cronobacter sakazakii ATCC BAA-894 5549118 YP_001436263.1 CDS ESA_00122 NC_009778.1 105269 107227 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(105269..107227) Cronobacter sakazakii ATCC BAA-894 5549082 YP_001436264.1 CDS gltP NC_009778.1 107652 108965 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 107652..108965 Cronobacter sakazakii ATCC BAA-894 5549176 YP_001436265.1 CDS ESA_00124 NC_009778.1 109641 109811 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(109641..109811) Cronobacter sakazakii ATCC BAA-894 5548924 YP_001436266.1 CDS ESA_00125 NC_009778.1 109866 110186 R Psort location: mitochondrial, score: 23; hypothetical protein complement(109866..110186) Cronobacter sakazakii ATCC BAA-894 5549039 YP_001436267.1 CDS ESA_00126 NC_009778.1 110398 112188 D KEGG: eci:UTI89_C0501 3.5e-25 htpG; chaperone HSP90, heat shock protein C 62.5 K04079; COG: COG0326 Molecular chaperone, HSP90 family; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 110398..112188 Cronobacter sakazakii ATCC BAA-894 5549026 YP_001436268.1 CDS ESA_00127 NC_009778.1 112188 114503 D KEGG: reh:H16_B0196 0.0085 sbcC; DNA repair exonuclease, SbcC K01146; COG: NOG06085 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 112188..114503 Cronobacter sakazakii ATCC BAA-894 5549046 YP_001436269.1 CDS ESA_00128 NC_009778.1 114539 114931 D COG: NOG10268 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 114539..114931 Cronobacter sakazakii ATCC BAA-894 5549055 YP_001436270.1 CDS ESA_00129 NC_009778.1 114617 114904 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(114617..114904) Cronobacter sakazakii ATCC BAA-894 5549068 YP_001436271.1 CDS phnH NC_009778.1 114928 115536 R COG: COG3625 Uncharacterized enzyme of phosphonate metabolism; Psort location: cytoplasmic, score: 23; carbon-phosphorus lyase complex subunit complement(114928..115536) Cronobacter sakazakii ATCC BAA-894 5549062 YP_001436272.1 CDS ESA_00131 NC_009778.1 115807 115938 D Psort location: mitochondrial, score: 23; hypothetical protein 115807..115938 Cronobacter sakazakii ATCC BAA-894 5552378 YP_001436273.1 CDS ESA_00132 NC_009778.1 116236 116571 R KEGG: eci:UTI89_C4702 1.4e-47 phnA; hypothetical protein PhnA K06193; COG: COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; Psort location: cytoplasmic, score: 23; hypothetical protein complement(116236..116571) Cronobacter sakazakii ATCC BAA-894 5549042 YP_001436274.1 CDS ESA_00133 NC_009778.1 117132 119495 D KEGG: reh:H16_A0378 0.0030 predicted GTPase K01529; COG: COG0699 Predicted GTPases (dynamin-related); Psort location: cytoplasmic, score: 23; hypothetical protein 117132..119495 Cronobacter sakazakii ATCC BAA-894 5549016 YP_001436275.1 CDS ESA_00134 NC_009778.1 119561 120358 D COG: NOG06779 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 119561..120358 Cronobacter sakazakii ATCC BAA-894 5549108 YP_001436276.1 CDS ESA_00135 NC_009778.1 120410 121414 R transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease complement(120410..121414) Cronobacter sakazakii ATCC BAA-894 5549037 YP_001436277.1 CDS ESA_00136 NC_009778.1 121401 121547 R Psort location: nuclear, score: 23; hypothetical protein complement(121401..121547) Cronobacter sakazakii ATCC BAA-894 5549112 YP_001436278.1 CDS ESA_00137 NC_009778.1 121805 122641 D 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 121805..122641 Cronobacter sakazakii ATCC BAA-894 5549090 YP_001436279.1 CDS ESA_00138 NC_009778.1 122692 123558 R YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU complement(122692..123558) Cronobacter sakazakii ATCC BAA-894 5549080 YP_001436280.1 CDS ESA_00139 NC_009778.1 123670 124632 R COG: COG2215 ABC-type uncharacterized transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(123670..124632) Cronobacter sakazakii ATCC BAA-894 5552056 YP_001436281.1 CDS ESA_00140 NC_009778.1 125239 125364 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(125239..125364) Cronobacter sakazakii ATCC BAA-894 5549198 YP_001436282.1 CDS ESA_00141 NC_009778.1 125547 126155 D COG: COG3455 Uncharacterized protein conserved in bacteria; Psort location: vesicles of secretory system, score: 9; hypothetical protein 125547..126155 Cronobacter sakazakii ATCC BAA-894 5550893 YP_001436283.1 CDS ESA_00142 NC_009778.1 126211 129339 D COG: COG3523 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 126211..129339 Cronobacter sakazakii ATCC BAA-894 5549125 YP_001436284.1 CDS ESA_00143 NC_009778.1 129340 131100 D COG: COG3519 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 129340..131100 Cronobacter sakazakii ATCC BAA-894 5552351 YP_001436285.1 CDS ESA_00144 NC_009778.1 131064 132164 D COG: COG3520 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 131064..132164 Cronobacter sakazakii ATCC BAA-894 5551150 YP_001436286.1 CDS ESA_00145 NC_009778.1 132172 132690 D COG: COG3521 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 132172..132690 Cronobacter sakazakii ATCC BAA-894 5549023 YP_001436287.1 CDS ESA_00147 NC_009778.1 133324 133899 R COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; putative transcriptional regulator complement(133324..133899) Cronobacter sakazakii ATCC BAA-894 5552227 YP_001436288.1 CDS dipZ NC_009778.1 133950 135674 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein precursor complement(133950..135674) Cronobacter sakazakii ATCC BAA-894 5549371 YP_001436289.1 CDS ESA_00149 NC_009778.1 135650 135997 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(135650..135997) Cronobacter sakazakii ATCC BAA-894 5551500 YP_001436290.1 CDS ESA_00150 NC_009778.1 136121 137422 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(136121..137422) Cronobacter sakazakii ATCC BAA-894 5551263 YP_001436291.1 CDS aspA NC_009778.1 137535 138971 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(137535..138971) Cronobacter sakazakii ATCC BAA-894 5551556 YP_001436292.1 CDS fxsA NC_009778.1 139309 139785 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 139309..139785 Cronobacter sakazakii ATCC BAA-894 5551549 YP_001436293.1 CDS ESA_00153 NC_009778.1 139922 140215 D KEGG: ftf:FTF1695 5.3e-23 groS; chaperonin protein, groES K04078; COG: COG0234 Co-chaperonin GroES (HSP10); Psort location: cytoplasmic, score: 23; hypothetical protein 139922..140215 Cronobacter sakazakii ATCC BAA-894 5549400 YP_001436294.1 CDS ESA_00154 NC_009778.1 140265 141908 D KEGG: eci:UTI89_C4741 1.4e-269 groEL; GroEL (chaperone HSP60) K04077; COG: COG0459 Chaperonin GroEL (HSP60 family); Psort location: cytoplasmic, score: 23; hypothetical protein 140265..141908 Cronobacter sakazakii ATCC BAA-894 5551490 YP_001436295.1 CDS ESA_00155 NC_009778.1 142138 142503 D COG: NOG09783 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 142138..142503 Cronobacter sakazakii ATCC BAA-894 5551531 YP_001436296.1 CDS ESA_00156 NC_009778.1 142882 143910 R KEGG: eci:UTI89_C4744 3.2e-158 yjeK; hypothetical protein YjeK K01843; COG: COG1509 Lysine 2,3-aminomutase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(142882..143910) Cronobacter sakazakii ATCC BAA-894 5551467 YP_001436297.1 CDS ESA_00157 NC_009778.1 143951 144517 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 143951..144517 Cronobacter sakazakii ATCC BAA-894 5552494 YP_001436298.1 CDS ESA_00158 NC_009778.1 144576 144707 D COG: COG5510 Predicted small secreted protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 144576..144707 Cronobacter sakazakii ATCC BAA-894 5549195 YP_001436299.1 CDS ESA_00159 NC_009778.1 144997 145665 R KEGG: ava:Ava_2028 0.0027 two component transcriptional regulator, LuxR family; COG: COG2771 DNA-binding HTH domain-containing proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(144997..145665) Cronobacter sakazakii ATCC BAA-894 5551561 YP_001436300.1 CDS ESA_00160 NC_009778.1 145880 146197 D COG: COG2076 Membrane transporters of cations and cationic drugs; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 145880..146197 Cronobacter sakazakii ATCC BAA-894 5549148 YP_001436301.1 CDS ESA_00161 NC_009778.1 146194 146733 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(146194..146733) Cronobacter sakazakii ATCC BAA-894 5549177 YP_001436302.1 CDS ESA_00162 NC_009778.1 146850 147209 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(146850..147209) Cronobacter sakazakii ATCC BAA-894 5549181 YP_001436303.1 CDS ESA_00163 NC_009778.1 147220 147618 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(147220..147618) Cronobacter sakazakii ATCC BAA-894 5549146 YP_001436304.1 CDS ESA_00164 NC_009778.1 147615 148361 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(147615..148361) Cronobacter sakazakii ATCC BAA-894 5549089 YP_001436305.1 CDS ESA_00165 NC_009778.1 148354 150222 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(148354..150222) Cronobacter sakazakii ATCC BAA-894 5549173 YP_001436306.1 CDS ESA_00166 NC_009778.1 150357 151424 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 150357..151424 Cronobacter sakazakii ATCC BAA-894 5549144 YP_001436307.1 CDS ESA_00167 NC_009778.1 151587 154919 R KEGG: syn:sll1583 1.8e-07 lig, ligA; DNA ligase K01972; COG: COG3264 Small-conductance mechanosensitive channel; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(151587..154919) Cronobacter sakazakii ATCC BAA-894 5549138 YP_001436308.1 CDS psd NC_009778.1 154936 155898 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(154936..155898) Cronobacter sakazakii ATCC BAA-894 5549107 YP_001436309.1 CDS ESA_00170 NC_009778.1 155995 156753 R KEGG: ssn:SSO_4346 1.6e-115 yjeQ; hypothetical protein K06949; COG: COG1162 Predicted GTPases; Psort location: mitochondrial, score: 23; hypothetical protein complement(155995..156753) Cronobacter sakazakii ATCC BAA-894 5549096 YP_001436310.1 CDS ESA_00169 NC_009778.1 156748 156999 D Psort location: cytoplasmic, score: 23; hypothetical protein 156748..156999 Cronobacter sakazakii ATCC BAA-894 5549141 YP_001436311.1 CDS ESA_00171 NC_009778.1 157141 157698 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 157141..157698 Cronobacter sakazakii ATCC BAA-894 5549180 YP_001436312.1 CDS ESA_00175 NC_009778.1 158238 158417 R Psort location: nuclear, score: 23; hypothetical protein complement(158238..158417) Cronobacter sakazakii ATCC BAA-894 5549092 YP_001436313.1 CDS ESA_00177 NC_009778.1 158430 159569 R COG: COG1600 Uncharacterized Fe-S protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(158430..159569) Cronobacter sakazakii ATCC BAA-894 5549153 YP_001436314.1 CDS ESA_00176 NC_009778.1 159568 161097 D KEGG: reh:H16_A1504 2.2e-63 predicted sugar kinase K00924; COG: COG0063 Predicted sugar kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 159568..161097 Cronobacter sakazakii ATCC BAA-894 5549170 YP_001436315.1 CDS ESA_00178 NC_009778.1 161090 161548 D possibly involved in cell wall synthesis; putative ATPase 161090..161548 Cronobacter sakazakii ATCC BAA-894 5549114 YP_001436316.1 CDS ESA_00179 NC_009778.1 161565 162911 D KEGG: eco:b4169 1.5e-183 amiB, yjeD; N-acetylmuramoyl-l-alanine amidase II, a murein hydrolase K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: extracellular, including cell wall, score: 9; N-acetylmuramoyl-l-alanine amidase II 161565..162911 Cronobacter sakazakii ATCC BAA-894 5552411 YP_001436317.1 CDS mutL NC_009778.1 162921 164828 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 162921..164828 Cronobacter sakazakii ATCC BAA-894 5549163 YP_001436318.1 CDS miaA NC_009778.1 164821 165771 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 164821..165771 Cronobacter sakazakii ATCC BAA-894 5549066 YP_001436319.1 CDS hfq NC_009778.1 165872 166180 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 165872..166180 Cronobacter sakazakii ATCC BAA-894 5549174 YP_001436320.1 CDS ESA_00183 NC_009778.1 166254 167534 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 166254..167534 Cronobacter sakazakii ATCC BAA-894 5549261 YP_001436321.1 CDS ESA_00184 NC_009778.1 167706 168950 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 167706..168950 Cronobacter sakazakii ATCC BAA-894 5549167 YP_001436322.1 CDS ESA_00185 NC_009778.1 168953 169957 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 168953..169957 Cronobacter sakazakii ATCC BAA-894 5549168 YP_001436323.1 CDS ESA_00186 NC_009778.1 170002 170217 D COG: COG3242 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 170002..170217 Cronobacter sakazakii ATCC BAA-894 5549160 YP_001436324.1 CDS ESA_00187 NC_009778.1 170320 171618 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 170320..171618 Cronobacter sakazakii ATCC BAA-894 5549256 YP_001436325.1 CDS ESA_00188 NC_009778.1 171698 172198 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 171698..172198 Cronobacter sakazakii ATCC BAA-894 5549169 YP_001436326.1 CDS ESA_00189 NC_009778.1 172235 174700 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 172235..174700 Cronobacter sakazakii ATCC BAA-894 5549132 YP_001436327.1 CDS ESA_00190 NC_009778.1 174782 175513 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 174782..175513 Cronobacter sakazakii ATCC BAA-894 5549240 YP_001436328.1 CDS ESA_00191 NC_009778.1 175691 176068 D COG: COG3766 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 175691..176068 Cronobacter sakazakii ATCC BAA-894 5551914 YP_001436329.1 CDS ESA_00192 NC_009778.1 176090 176746 D COG: COG5463 Predicted integral membrane protein; Psort location: nuclear, score: 23; hypothetical protein 176090..176746 Cronobacter sakazakii ATCC BAA-894 5549412 YP_001436330.1 CDS ESA_00193 NC_009778.1 176747 177934 D KEGG: vvy:VV2267 1.8e-102 glutaTHIonylspermidine synthase K01917; COG: COG0754 GlutaTHIonylspermidine synthase; Psort location: cytoplasmic, score: 23; hypothetical protein 176747..177934 Cronobacter sakazakii ATCC BAA-894 5549257 YP_001436331.1 CDS ESA_00194 NC_009778.1 178025 179659 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 178025..179659 Cronobacter sakazakii ATCC BAA-894 5549260 YP_001436332.1 CDS ESA_00195 NC_009778.1 179660 181591 R KEGG: reh:H16_B1458 2.3e-10 signal transduction histidine kinase; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(179660..181591) Cronobacter sakazakii ATCC BAA-894 5549317 YP_001436333.1 CDS ESA_00196 NC_009778.1 181652 181912 D Psort location: cytoplasmic, score: 23; hypothetical protein 181652..181912 Cronobacter sakazakii ATCC BAA-894 5549282 YP_001436334.1 CDS ESA_00197 NC_009778.1 181739 182014 R COG: NOG11343 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(181739..182014) Cronobacter sakazakii ATCC BAA-894 5549281 YP_001436335.1 CDS ESA_00198 NC_009778.1 182150 182458 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A complement(182150..182458) Cronobacter sakazakii ATCC BAA-894 5549384 YP_001436336.1 CDS ESA_00199 NC_009778.1 182622 183389 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 182622..183389 Cronobacter sakazakii ATCC BAA-894 5549299 YP_001436337.1 CDS rpsF NC_009778.1 183561 183956 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 183561..183956 Cronobacter sakazakii ATCC BAA-894 5549293 YP_001436338.1 CDS ESA_00201 NC_009778.1 183962 184276 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 183962..184276 Cronobacter sakazakii ATCC BAA-894 5549362 YP_001436339.1 CDS rpsR NC_009778.1 184281 184508 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 184281..184508 Cronobacter sakazakii ATCC BAA-894 5552252 YP_001436341.1 CDS rplI NC_009778.1 184550 184999 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 184550..184999 Cronobacter sakazakii ATCC BAA-894 5549188 YP_001436342.1 CDS ESA_00205 NC_009778.1 185072 185650 R COG: COG3061 Cell envelope opacity-associated protein A; Psort location: nuclear, score: 23; hypothetical protein complement(185072..185650) Cronobacter sakazakii ATCC BAA-894 5549413 YP_001436343.1 CDS ESA_00207 NC_009778.1 185668 185853 R Psort location: mitochondrial, score: 23; hypothetical protein complement(185668..185853) Cronobacter sakazakii ATCC BAA-894 5549273 YP_001436344.1 CDS ESA_00206 NC_009778.1 185852 186472 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 185852..186472 Cronobacter sakazakii ATCC BAA-894 5549236 YP_001436345.1 CDS ESA_00208 NC_009778.1 186762 188174 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 186762..188174 Cronobacter sakazakii ATCC BAA-894 5549099 YP_001436346.1 CDS ESA_00209 NC_009778.1 188244 188909 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(188244..188909) Cronobacter sakazakii ATCC BAA-894 5549294 YP_001436347.1 CDS ESA_00211 NC_009778.1 188992 189153 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(188992..189153) Cronobacter sakazakii ATCC BAA-894 5549379 YP_001436348.1 CDS ESA_00210 NC_009778.1 189152 190825 D KEGG: rde:RD1_3666 2.0e-06 torS; sensor protein TorS; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 189152..190825 Cronobacter sakazakii ATCC BAA-894 5549325 YP_001436349.1 CDS ESA_00212 NC_009778.1 190857 191828 R KEGG: sfl:SF3793 0.0092 uhpB; sensor histidine protein kinase phosphorylates UhpA K07675; COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(190857..191828) Cronobacter sakazakii ATCC BAA-894 5549255 YP_001436350.1 CDS ESA_00213 NC_009778.1 191905 192486 R COG: COG3506 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(191905..192486) Cronobacter sakazakii ATCC BAA-894 5549235 YP_001436351.1 CDS ESA_00214 NC_009778.1 192499 193425 R KEGG: bce:BC3740 3.3e-10 ADA regulatory protein K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(192499..193425) Cronobacter sakazakii ATCC BAA-894 5549295 YP_001436352.1 CDS ESA_00215 NC_009778.1 193442 193867 R COG: COG3755 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(193442..193867) Cronobacter sakazakii ATCC BAA-894 5549250 YP_001436353.1 CDS ESA_00217 NC_009778.1 193911 194765 R KEGG: eci:UTI89_C4820 1.4e-102 ytfG; hypothetical protein YtfG; COG: COG0702 Predicted nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(193911..194765) Cronobacter sakazakii ATCC BAA-894 5549320 YP_001436354.1 CDS ESA_00216 NC_009778.1 194764 195234 D COG: COG1733 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 194764..195234 Cronobacter sakazakii ATCC BAA-894 5549408 YP_001436355.1 CDS cpdB NC_009778.1 195479 197422 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein complement(195479..197422) Cronobacter sakazakii ATCC BAA-894 5549301 YP_001436356.1 CDS ESA_00219 NC_009778.1 197638 198387 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 197638..198387 Cronobacter sakazakii ATCC BAA-894 5549395 YP_001436357.1 CDS ESA_00220 NC_009778.1 198377 198934 R COG: COG3054 Predicted transcriptional regulator; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(198377..198934) Cronobacter sakazakii ATCC BAA-894 5549221 YP_001436358.1 CDS ESA_00222 NC_009778.1 198931 199212 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(198931..199212) Cronobacter sakazakii ATCC BAA-894 5551687 YP_001436359.1 CDS ESA_00221 NC_009778.1 199211 199468 D COG: NOG17567 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 199211..199468 Cronobacter sakazakii ATCC BAA-894 5549913 YP_001436360.1 CDS ESA_00223 NC_009778.1 199532 200863 R KEGG: hpa:HPAG1_1423 6.5e-41 putative integral membrane protein with a TlyC-like hemolysin domain K00088; COG: COG1253 Hemolysins and related proteins containing CBS domains; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(199532..200863) Cronobacter sakazakii ATCC BAA-894 5549279 YP_001436361.1 CDS ESA_00224 NC_009778.1 201062 202477 R COG: NOG24086 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(201062..202477) Cronobacter sakazakii ATCC BAA-894 5552340 YP_001436362.1 CDS ESA_00225 NC_009778.1 202583 203221 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(202583..203221) Cronobacter sakazakii ATCC BAA-894 5551530 YP_001436363.1 CDS ESA_00226 NC_009778.1 203218 203355 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(203218..203355) Cronobacter sakazakii ATCC BAA-894 5551466 YP_001436364.1 CDS ESA_00227 NC_009778.1 203464 205179 D COG: COG0729 Outer membrane protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 203464..205179 Cronobacter sakazakii ATCC BAA-894 5549890 YP_001436365.1 CDS ESA_00228 NC_009778.1 205176 208952 D KEGG: bmf:BAB1_0046 1.2e-13 family of unknown function DUF490 K01076; COG: COG2911 Uncharacterized protein conserved in bacteria; Psort location: mitochondrial, score: 23; hypothetical protein 205176..208952 Cronobacter sakazakii ATCC BAA-894 5549957 YP_001436366.1 CDS ESA_00229 NC_009778.1 209009 209290 D COG: COG2105 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 209009..209290 Cronobacter sakazakii ATCC BAA-894 5549960 YP_001436367.1 CDS ESA_00230 NC_009778.1 209538 211133 D KEGG: gvi:glr0861 2.7e-05 two-component sensor histidine kinase; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 209538..211133 Cronobacter sakazakii ATCC BAA-894 5552311 YP_001436368.1 CDS ESA_00231 NC_009778.1 211185 211712 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(211185..211712) Cronobacter sakazakii ATCC BAA-894 5549951 YP_001436369.1 CDS ESA_00232 NC_009778.1 211779 211919 D Psort location: cytoplasmic, score: 23; hypothetical protein 211779..211919 Cronobacter sakazakii ATCC BAA-894 5549961 YP_001436370.1 CDS ESA_00233 NC_009778.1 211911 212036 R Psort location: nuclear, score: 23; hypothetical protein complement(211911..212036) Cronobacter sakazakii ATCC BAA-894 5549975 YP_001436371.1 CDS ESA_00234 NC_009778.1 212114 213070 D KEGG: msm:MSMEG_3095 2.0e-30 D-ribose-binding periplasmic protein; COG: COG1879 ABC-type sugar transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 212114..213070 Cronobacter sakazakii ATCC BAA-894 5549985 YP_001436372.1 CDS ESA_00236 NC_009778.1 213268 213396 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(213268..213396) Cronobacter sakazakii ATCC BAA-894 5549963 YP_001436373.1 CDS ESA_00235 NC_009778.1 213316 214818 D KEGG: eco:b4485 1.4e-228 ytfR, ytfS; predicted sugar transporter subunit: ATP-binding component of ABC superfamily K02056; COG: COG1129 ABC-type sugar transport system, ATPase component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 213316..214818 Cronobacter sakazakii ATCC BAA-894 5549993 YP_001436374.1 CDS ESA_00237 NC_009778.1 214892 215854 D KEGG: msm:MSMEG_1710 1.5e-73 ribose transport system permease protein RbsC; COG: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 214892..215854 Cronobacter sakazakii ATCC BAA-894 5549964 YP_001436375.1 CDS ESA_00238 NC_009778.1 215841 216830 D membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease protein YjfF 215841..216830 Cronobacter sakazakii ATCC BAA-894 5549994 YP_001436376.1 CDS ESA_00239 NC_009778.1 216941 218506 D KEGG: abo:ABO_1307 7.4e-06 sensor histidine kinase/respose regulator; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 216941..218506 Cronobacter sakazakii ATCC BAA-894 5549973 YP_001436377.1 CDS ESA_00240 NC_009778.1 218789 219787 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(218789..219787) Cronobacter sakazakii ATCC BAA-894 5550008 YP_001436378.1 CDS ESA_00241 NC_009778.1 219963 221342 D KEGG: stm:STM4416 2.4e-233 mpl; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase K02558; COG: COG0773 UDP-N-acetylmuramate-alanine ligase; Psort location: mitochondrial, score: 23; hypothetical protein 219963..221342 Cronobacter sakazakii ATCC BAA-894 5550023 YP_001436379.1 CDS ESA_00242 NC_009778.1 221399 222607 R COG: NOG10872 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(221399..222607) Cronobacter sakazakii ATCC BAA-894 5550000 YP_001436380.1 CDS ESA_00243 NC_009778.1 222931 223482 R COG: COG3028 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(222931..223482) Cronobacter sakazakii ATCC BAA-894 5550011 YP_001436381.1 CDS ESA_00244 NC_009778.1 223590 224942 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 223590..224942 Cronobacter sakazakii ATCC BAA-894 5552407 YP_001436382.1 CDS ESA_00245 NC_009778.1 225000 225386 D KEGG: eco:b4236 1.8e-36 cybC; cytochrome b562, truncated (pseudogene); COG: COG3783 Soluble cytochrome b562; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 225000..225386 Cronobacter sakazakii ATCC BAA-894 5550028 YP_001436383.1 CDS ESA_00246 NC_009778.1 225466 225657 D Psort location: mitochondrial, score: 23; hypothetical protein 225466..225657 Cronobacter sakazakii ATCC BAA-894 5550030 YP_001436384.1 CDS ESA_00247 NC_009778.1 225709 226032 D COG: NOG18554 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 225709..226032 Cronobacter sakazakii ATCC BAA-894 5550021 YP_001436385.1 CDS ESA_00248 NC_009778.1 226049 226411 D COG: NOG11467 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 226049..226411 Cronobacter sakazakii ATCC BAA-894 5552475 YP_001436386.1 CDS ESA_00249 NC_009778.1 226415 226717 D COG: NOG18555 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 226415..226717 Cronobacter sakazakii ATCC BAA-894 5550072 YP_001436387.1 CDS ESA_00250 NC_009778.1 226740 227516 D COG: NOG07923 non supervised orthologous group; Psort location: plasma membrane, score: 23; hypothetical protein 226740..227516 Cronobacter sakazakii ATCC BAA-894 5550081 YP_001436388.1 CDS ESA_00251 NC_009778.1 227524 228171 D KEGG: rpa:RPA1257 0.0038 cobS; possible cobalamin (5'-phosphate) synthase K02233; COG: NOG08746 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 227524..228171 Cronobacter sakazakii ATCC BAA-894 5550067 YP_001436389.1 CDS ESA_00252 NC_009778.1 228212 229111 D KEGG: btl:BALH_4413 1.2e-62 possible dihydroorotase K01486; COG: COG3964 Predicted amidohydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein 228212..229111 Cronobacter sakazakii ATCC BAA-894 5550070 YP_001436390.1 CDS ESA_00253 NC_009778.1 229104 229346 D KEGG: pcr:Pcryo_1934 3.4e-05 imidazolonepropionase K01468; COG: COG3964 Predicted amidohydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein 229104..229346 Cronobacter sakazakii ATCC BAA-894 5550066 YP_001436391.1 CDS ESA_00254 NC_009778.1 229339 230448 D KEGG: efa:EF0838 2.3e-102 pyridoxal phosphate-dependent enzyme, putative K01042; COG: COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; Psort location: cytoplasmic, score: 23; hypothetical protein 229339..230448 Cronobacter sakazakii ATCC BAA-894 5550092 YP_001436392.1 CDS ESA_00255 NC_009778.1 230445 231185 D KEGG: msm:MSMEG_3788 7.9e-05 eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625:K01650; COG: NOG08125 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 230445..231185 Cronobacter sakazakii ATCC BAA-894 5550090 YP_001436393.1 CDS ESA_00256 NC_009778.1 231299 233209 D KEGG: spi:MGAS10750_Spy1176 1.1e-32 transcription antiterminator, BglG family / PTS system, mannitol (cryptic)-specific IIA component K00890; COG: COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; Psort location: cytoplasmic, score: 23; hypothetical protein 231299..233209 Cronobacter sakazakii ATCC BAA-894 5550075 YP_001436394.1 CDS ESA_00257 NC_009778.1 233287 233529 D Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB 233287..233529 Cronobacter sakazakii ATCC BAA-894 5550105 YP_001436395.1 CDS ESA_00258 NC_009778.1 233519 233806 D COG: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; Psort location: cytoplasmic, score: 23; hypothetical protein 233519..233806 Cronobacter sakazakii ATCC BAA-894 5550109 YP_001436396.1 CDS nrdG NC_009778.1 233814 234278 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(233814..234278) Cronobacter sakazakii ATCC BAA-894 5550095 YP_001436397.1 CDS ESA_00260 NC_009778.1 234574 236709 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(234574..236709) Cronobacter sakazakii ATCC BAA-894 5550104 YP_001436398.1 CDS ESA_00261 NC_009778.1 237006 237887 R KEGG: shn:Shewana3_3435 5.2e-07 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(237006..237887) Cronobacter sakazakii ATCC BAA-894 5550115 YP_001436399.1 CDS ESA_00262 NC_009778.1 237990 238520 D KEGG: gvi:glr1342 5.1e-41 probable NADP(H) oxidoreductase; COG: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); Psort location: cytoplasmic, score: 23; hypothetical protein 237990..238520 Cronobacter sakazakii ATCC BAA-894 5550146 YP_001436400.1 CDS ESA_00263 NC_009778.1 238531 240192 R KEGG: stt:t4488 3.0e-249 treC; trehalose-6-phosphate hydrolase K01226; COG: COG0366 Glycosidases; Psort location: cytoplasmic, score: 23; trehalose-6-phosphate hydrolase complement(238531..240192) Cronobacter sakazakii ATCC BAA-894 5550140 YP_001436401.1 CDS ESA_00264 NC_009778.1 240253 241671 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC complement(240253..241671) Cronobacter sakazakii ATCC BAA-894 5550134 YP_001436402.1 CDS treR NC_009778.1 241806 242753 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(241806..242753) Cronobacter sakazakii ATCC BAA-894 5550114 YP_001436403.1 CDS ESA_00266 NC_009778.1 243001 243618 R COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(243001..243618) Cronobacter sakazakii ATCC BAA-894 5550128 YP_001436404.1 CDS ESA_00267 NC_009778.1 243795 244442 D cofactor involved in the reduction of disulfides; glutaredoxin 2 243795..244442 Cronobacter sakazakii ATCC BAA-894 5550141 YP_001436405.1 CDS ESA_00268 NC_009778.1 244501 244803 D COG: COG1359 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 244501..244803 Cronobacter sakazakii ATCC BAA-894 5550127 YP_001436406.1 CDS ESA_00269 NC_009778.1 244863 245372 R COG: NOG06777 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(244863..245372) Cronobacter sakazakii ATCC BAA-894 5550120 YP_001436407.1 CDS dkgA NC_009778.1 245449 246276 R methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A complement(245449..246276) Cronobacter sakazakii ATCC BAA-894 5550119 YP_001436408.1 CDS ESA_00271 NC_009778.1 246382 247545 R KEGG: eco:b3011 1.6e-181 yqhD; putative alcohol dehydrogenase K08325; COG: COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(246382..247545) Cronobacter sakazakii ATCC BAA-894 5550098 YP_001436409.1 CDS ESA_00272 NC_009778.1 247736 248629 D KEGG: bli:BL05281 1.1e-07 adaA; methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 247736..248629 Cronobacter sakazakii ATCC BAA-894 5550123 YP_001436410.1 CDS ESA_00273 NC_009778.1 248658 249311 R KEGG: sab:SAB2386 9.1e-08 probable alkaline phosphatase K01077; COG: COG0586 Uncharacterized membrane-associated protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(248658..249311) Cronobacter sakazakii ATCC BAA-894 5550121 YP_001436411.1 CDS ESA_00275 NC_009778.1 250640 250819 D Psort location: mitochondrial, score: 23; hypothetical protein 250640..250819 Cronobacter sakazakii ATCC BAA-894 5550083 YP_001436412.1 CDS ESA_00276 NC_009778.1 250879 251598 D membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 250879..251598 Cronobacter sakazakii ATCC BAA-894 5550073 YP_001436413.1 CDS ESA_00277 NC_009778.1 251603 252028 D membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 251603..252028 Cronobacter sakazakii ATCC BAA-894 5549991 YP_001436414.1 CDS ESA_00278 NC_009778.1 252097 252993 R KEGG: sec:SC3099 7.8e-132 yghA; putative oxidoreductase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; oxidoreductase complement(252097..252993) Cronobacter sakazakii ATCC BAA-894 5550022 YP_001436415.1 CDS ESA_00279 NC_009778.1 253163 253903 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 253163..253903 Cronobacter sakazakii ATCC BAA-894 5550035 YP_001436416.1 CDS ESA_00280 NC_009778.1 253889 254308 R COG: NOG30084 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(253889..254308) Cronobacter sakazakii ATCC BAA-894 5552294 YP_001436417.1 CDS ESA_00281 NC_009778.1 254314 254715 R COG: NOG27696 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(254314..254715) Cronobacter sakazakii ATCC BAA-894 5549972 YP_001436418.1 CDS ESA_00282 NC_009778.1 254821 255321 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 254821..255321 Cronobacter sakazakii ATCC BAA-894 5549918 YP_001436419.1 CDS ESA_00283 NC_009778.1 255397 255894 D COG: COG2862 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 255397..255894 Cronobacter sakazakii ATCC BAA-894 5549917 YP_001436420.1 CDS ESA_00284 NC_009778.1 256057 257187 D KEGG: rle:pRL120603 0.0043 gabD; putative succinate-semialdehyde dehydrogenase (NADP+) K00135; COG: COG0668 Small-conductance mechanosensitive channel; Psort location: plasma membrane, score: 23; hypothetical protein 256057..257187 Cronobacter sakazakii ATCC BAA-894 5549954 YP_001436421.1 CDS ESA_00285 NC_009778.1 257260 258639 R COG: COG4580 Maltoporin (phage lambda and maltose receptor); Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(257260..258639) Cronobacter sakazakii ATCC BAA-894 5551124 YP_001436422.1 CDS ESA_00286 NC_009778.1 258800 259105 R KEGG: eca:ECA2489 3.1e-41 PTS system, cellobiose-specific IIa component K02759; COG: COG1447 Phosphotransferase system cellobiose-specific component IIA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(258800..259105) Cronobacter sakazakii ATCC BAA-894 5549936 YP_001436423.1 CDS ESA_00287 NC_009778.1 259241 260545 R KEGG: eca:ECA2488 1.5e-194 PTS system, cellobiose-specific IIc component K02761; COG: COG1455 Phosphotransferase system cellobiose-specific component IIC; Psort location: plasma membrane, score: 23; hypothetical protein complement(259241..260545) Cronobacter sakazakii ATCC BAA-894 5551501 YP_001436424.1 CDS ESA_00288 NC_009778.1 260583 260897 R KEGG: ppr:PBPRB2008 2.5e-32 celA; hypothetical cellobiose-specific IIB component, PTS system K02760; COG: COG1440 Phosphotransferase system cellobiose-specific component IIB; Psort location: cytoplasmic, score: 23; hypothetical protein complement(260583..260897) Cronobacter sakazakii ATCC BAA-894 5551259 YP_001436425.1 CDS ESA_00290 NC_009778.1 261034 261201 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(261034..261201) Cronobacter sakazakii ATCC BAA-894 5551778 YP_001436426.1 CDS ESA_00289 NC_009778.1 261188 262141 D KEGG: efa:EF1922 0.00016 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 261188..262141 Cronobacter sakazakii ATCC BAA-894 5552324 YP_001436427.1 CDS ESA_00291 NC_009778.1 262169 262789 R KEGG: fal:FRAAL1007 0.0016 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179; COG: COG3647 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(262169..262789) Cronobacter sakazakii ATCC BAA-894 5552382 YP_001436428.1 CDS ESA_00292 NC_009778.1 263518 265632 D COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 263518..265632 Cronobacter sakazakii ATCC BAA-894 5552205 YP_001436429.1 CDS ESA_00293 NC_009778.1 265948 267666 D KEGG: cvi:CV0024 4.0e-43 probable hydroxyethylTHIazole kinase K00878; COG: NOG11775 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 265948..267666 Cronobacter sakazakii ATCC BAA-894 5549742 YP_001436430.1 CDS ESA_00294 NC_009778.1 267668 268159 D Psort location: mitochondrial, score: 23; hypothetical protein 267668..268159 Cronobacter sakazakii ATCC BAA-894 5549864 YP_001436431.1 CDS ESA_00295 NC_009778.1 268168 268290 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(268168..268290) Cronobacter sakazakii ATCC BAA-894 5549740 YP_001436432.1 CDS ESA_00296 NC_009778.1 268184 268327 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(268184..268327) Cronobacter sakazakii ATCC BAA-894 5549767 YP_001436433.1 CDS ESA_00297 NC_009778.1 268403 268708 D Psort location: cytoplasmic, score: 23; hypothetical protein 268403..268708 Cronobacter sakazakii ATCC BAA-894 5549754 YP_001436434.1 CDS ESA_00298 NC_009778.1 268708 269970 D COG: NOG25000 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 268708..269970 Cronobacter sakazakii ATCC BAA-894 5549793 YP_001436435.1 CDS ESA_00299 NC_009778.1 269982 271178 D COG: NOG18467 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 269982..271178 Cronobacter sakazakii ATCC BAA-894 5549716 YP_001436436.1 CDS ESA_00300 NC_009778.1 271228 272424 D COG: NOG18467 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 271228..272424 Cronobacter sakazakii ATCC BAA-894 5552380 YP_001436437.1 CDS ESA_00301 NC_009778.1 273057 273221 R Psort location: nuclear, score: 23; hypothetical protein complement(273057..273221) Cronobacter sakazakii ATCC BAA-894 5549797 YP_001436438.1 CDS ESA_00302 NC_009778.1 273419 273568 D Psort location: cytoplasmic, score: 23; hypothetical protein 273419..273568 Cronobacter sakazakii ATCC BAA-894 5549810 YP_001436439.1 CDS ESA_00303 NC_009778.1 273598 275001 D KEGG: fal:FRAAL6221 1.2e-58 putative poly(beta-D-mannuronate) O-acetylase (alginate biosynthesis protein AlgI) K00680; COG: COG1696 Predicted membrane protein involved in D-alanine export; Psort location: plasma membrane, score: 23; hypothetical protein 273598..275001 Cronobacter sakazakii ATCC BAA-894 5549873 YP_001436440.1 CDS ESA_00304 NC_009778.1 274988 276091 D KEGG: cme:CMM178C 0.0089 NADH dehydrogenase type II, chloroplast precursor K03885; COG: COG2845 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 274988..276091 Cronobacter sakazakii ATCC BAA-894 5549882 YP_001436441.1 CDS ESA_00305 NC_009778.1 276263 277291 D COG: COG2755 Lysophospholipase L1 and related esterases; Psort location: cytoplasmic, score: 23; hypothetical protein 276263..277291 Cronobacter sakazakii ATCC BAA-894 5549881 YP_001436442.1 CDS ESA_00306 NC_009778.1 277746 279440 D COG: COG4685 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 23; hypothetical protein 277746..279440 Cronobacter sakazakii ATCC BAA-894 5549876 YP_001436443.1 CDS ESA_00307 NC_009778.1 279437 280093 D COG: COG3234 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 279437..280093 Cronobacter sakazakii ATCC BAA-894 5549863 YP_001436444.1 CDS ESA_00308 NC_009778.1 280111 284652 D COG: COG2373 Large extracellular alpha-helical protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 280111..284652 Cronobacter sakazakii ATCC BAA-894 5549879 YP_001436445.1 CDS ESA_00309 NC_009778.1 284656 286302 D COG: COG5445 Predicted secreted protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 284656..286302 Cronobacter sakazakii ATCC BAA-894 5549857 YP_001436446.1 CDS ESA_00310 NC_009778.1 286299 287078 D COG: COG4676 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 286299..287078 Cronobacter sakazakii ATCC BAA-894 5551880 YP_001436447.1 CDS ESA_00312 NC_009778.1 287620 288240 R COG: COG1811 Uncharacterized membrane protein, possible Na+ channel or pump; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(287620..288240) Cronobacter sakazakii ATCC BAA-894 5552177 YP_001436448.1 CDS ESA_00313 NC_009778.1 288441 288569 D Psort location: mitochondrial, score: 23; hypothetical protein 288441..288569 Cronobacter sakazakii ATCC BAA-894 5549880 YP_001436449.1 CDS ESA_00314 NC_009778.1 288885 291023 D KEGG: ecc:c3553 0. speC; orniTHIne decarboxylase, constitutive K01581; COG: COG1982 Arginine/lysine/orniTHIne decarboxylases; Psort location: extracellular, including cell wall, score: 9; ornithine decarboxylase 288885..291023 Cronobacter sakazakii ATCC BAA-894 5552238 YP_001436450.1 CDS ESA_00315 NC_009778.1 291287 291982 R KEGG: btl:BALH_0517 2.1e-21 response regulator; COG: COG4565 Response regulator of citrate/malate metabolism; Psort location: cytoplasmic, score: 23; hypothetical protein complement(291287..291982) Cronobacter sakazakii ATCC BAA-894 5552085 YP_001436451.1 CDS ESA_00316 NC_009778.1 291972 293606 R KEGG: eca:ECA2577 7.1e-170 citA; two-component sensor kinase K07700; COG: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(291972..293606) Cronobacter sakazakii ATCC BAA-894 5552215 YP_001436452.1 CDS ESA_00317 NC_009778.1 293739 293939 D Psort location: mitochondrial, score: 23; hypothetical protein 293739..293939 Cronobacter sakazakii ATCC BAA-894 5551888 YP_001436453.1 CDS ESA_00318 NC_009778.1 293944 295308 D COG: COG3493 Na+/citrate symporter; Psort location: plasma membrane, score: 23; hypothetical protein 293944..295308 Cronobacter sakazakii ATCC BAA-894 5552080 YP_001436454.1 CDS ESA_00319 NC_009778.1 295327 296190 D KEGG: reu:Reut_B5809 3.0e-68 5-carboxymethyl-2-hydroxymuconate delta-isomerase K01826; COG: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); Psort location: cytoplasmic, score: 23; hypothetical protein 295327..296190 Cronobacter sakazakii ATCC BAA-894 5552076 YP_001436455.1 CDS ESA_00320 NC_009778.1 296208 297239 D KEGG: eca:ECA2574 1.6e-94 citC; [citrate [pro-3s]-lyase] ligase K01910; COG: COG3053 Citrate lyase synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein 296208..297239 Cronobacter sakazakii ATCC BAA-894 5552220 YP_001436456.1 CDS ESA_00321 NC_009778.1 297266 297559 D acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 297266..297559 Cronobacter sakazakii ATCC BAA-894 5551982 YP_001436457.1 CDS ESA_00322 NC_009778.1 297556 298431 D KEGG: eca:ECA2572 3.0e-130 citE; citrate lyase beta chain K01644; COG: COG2301 Citrate lyase beta subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 297556..298431 Cronobacter sakazakii ATCC BAA-894 5551798 YP_001436458.1 CDS ESA_00323 NC_009778.1 298442 298909 D KEGG: eca:ECA2571 2.8e-49 citF; citrate lyase alpha chain K01643; COG: COG3051 Citrate lyase, alpha subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 298442..298909 Cronobacter sakazakii ATCC BAA-894 5549363 YP_001436459.1 CDS ESA_00325 NC_009778.1 298773 299831 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(298773..299831) Cronobacter sakazakii ATCC BAA-894 5549430 YP_001436460.1 CDS ESA_00324 NC_009778.1 298884 299960 D KEGG: eca:ECA2571 8.8e-156 citF; citrate lyase alpha chain K01643; COG: COG3051 Citrate lyase, alpha subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 298884..299960 Cronobacter sakazakii ATCC BAA-894 5549328 YP_001436461.1 CDS ESA_00326 NC_009778.1 299964 300503 D KEGG: eca:ECA2570 1.7e-40 citX; apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964; COG: COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase); Psort location: cytoplasmic, score: 23; hypothetical protein 299964..300503 Cronobacter sakazakii ATCC BAA-894 5549305 YP_001436462.1 CDS ESA_00327 NC_009778.1 300481 301323 D KEGG: eca:ECA2569 2.0e-71 citG; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase K05966; COG: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein 300481..301323 Cronobacter sakazakii ATCC BAA-894 5549377 YP_001436463.1 CDS mltC NC_009778.1 301562 302647 R Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C complement(301562..302647) Cronobacter sakazakii ATCC BAA-894 5549378 YP_001436464.1 CDS ESA_00329 NC_009778.1 302689 302964 R COG: COG2924 Fe-S cluster protector protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(302689..302964) Cronobacter sakazakii ATCC BAA-894 5549527 YP_001436465.1 CDS ESA_00330 NC_009778.1 302967 304052 R KEGG: spt:SPA2973 8.0e-162 mutY; A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: cytoplasmic, score: 23; adenine DNA glycosylase complement(302967..304052) Cronobacter sakazakii ATCC BAA-894 5549409 YP_001436466.1 CDS trmB NC_009778.1 304205 304924 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 304205..304924 Cronobacter sakazakii ATCC BAA-894 5549297 YP_001436467.1 CDS ESA_00332 NC_009778.1 304924 305250 D COG: COG3171 Uncharacterized protein conserved in bacteria; Psort location: mitochondrial, score: 23; hypothetical protein 304924..305250 Cronobacter sakazakii ATCC BAA-894 5549381 YP_001436468.1 CDS ESA_00333 NC_009778.1 305301 306017 D COG: NOG06291 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 305301..306017 Cronobacter sakazakii ATCC BAA-894 5549396 YP_001436469.1 CDS ESA_00334 NC_009778.1 306164 306523 D Psort location: mitochondrial, score: 23; hypothetical protein 306164..306523 Cronobacter sakazakii ATCC BAA-894 5549302 YP_001436470.1 CDS ESA_00335 NC_009778.1 306646 306783 D Psort location: cytoplasmic, score: 23; hypothetical protein 306646..306783 Cronobacter sakazakii ATCC BAA-894 5549367 YP_001436471.1 CDS ESA_00336 NC_009778.1 306927 307364 D COG: COG1598 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 306927..307364 Cronobacter sakazakii ATCC BAA-894 5549373 YP_001436472.1 CDS ESA_00337 NC_009778.1 307394 308359 R KEGG: reh:H16_A0195 5.9e-56 putative GTPase (G3E family); COG: COG0523 Putative GTPases (G3E family); Psort location: cytoplasmic, score: 23; putative GTP-binding protein YjiA complement(307394..308359) Cronobacter sakazakii ATCC BAA-894 5549267 YP_001436473.1 CDS ESA_00338 NC_009778.1 308378 308581 R COG: COG2879 Uncharacterized small protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(308378..308581) Cronobacter sakazakii ATCC BAA-894 5549300 YP_001436474.1 CDS ESA_00339 NC_009778.1 308842 310995 R COG: COG1966 Carbon starvation protein, predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(308842..310995) Cronobacter sakazakii ATCC BAA-894 5549407 YP_001436475.1 CDS ESA_00340 NC_009778.1 311834 313882 D KEGG: reh:H16_B0196 2.4e-05 sbcC; DNA repair exonuclease, SbcC K01146; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 311834..313882 Cronobacter sakazakii ATCC BAA-894 5549360 YP_001436476.1 CDS ESA_00341 NC_009778.1 313854 314600 D KEGG: chu:CHU_2038 1.8e-20 crtZ; beta-carotene hydroxylase K00492; COG: NOG14527 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 313854..314600 Cronobacter sakazakii ATCC BAA-894 5549711 YP_001436477.1 CDS ESA_00342 NC_009778.1 314488 315459 R KEGG: plu:plu4343 3.8e-100 crtB; phytoene synthase K02291; COG: COG1562 Phytoene/squalene synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(314488..315459) Cronobacter sakazakii ATCC BAA-894 5549402 YP_001436478.1 CDS ESA_00343 NC_009778.1 315456 316934 R KEGG: rsp:RSP_0271 2.0e-101 crtI; phytoene dehydrogenase K00258; COG: COG1233 Phytoene dehydrogenase and related proteins; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(315456..316934) Cronobacter sakazakii ATCC BAA-894 5549327 YP_001436479.1 CDS ESA_00344 NC_009778.1 316927 318102 R KEGG: syc:syc2031_d 4.5e-06 crtL; lycopene cyclase K06444; COG: NOG08858 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(316927..318102) Cronobacter sakazakii ATCC BAA-894 5549326 YP_001436480.1 CDS ESA_00345 NC_009778.1 318099 319373 R KEGG: mxa:MXAN_0593 9.1e-16 glycosyltransferase, MGT family K00754; COG: COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(318099..319373) Cronobacter sakazakii ATCC BAA-894 5549350 YP_001436481.1 CDS ESA_00346 NC_009778.1 319370 320413 R catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase complement(319370..320413) Cronobacter sakazakii ATCC BAA-894 5549433 YP_001436482.1 CDS ESA_00347 NC_009778.1 320456 321361 R KEGG: hne:HNE_1839 2.3e-38 ispA; geranyltranstransferase K00795; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(320456..321361) Cronobacter sakazakii ATCC BAA-894 5549508 YP_001436483.1 CDS ESA_00348 NC_009778.1 321623 322171 R COG: COG3054 Predicted transcriptional regulator; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(321623..322171) Cronobacter sakazakii ATCC BAA-894 5549669 YP_001436484.1 CDS ESA_00349 NC_009778.1 322329 322700 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 322329..322700 Cronobacter sakazakii ATCC BAA-894 5549671 YP_001436485.1 CDS ESA_00350 NC_009778.1 323959 324216 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(323959..324216) Cronobacter sakazakii ATCC BAA-894 5552361 YP_001436486.1 CDS ESA_00351 NC_009778.1 324492 324617 R Psort location: nuclear, score: 23; hypothetical protein complement(324492..324617) Cronobacter sakazakii ATCC BAA-894 5549465 YP_001436487.1 CDS ESA_00353 NC_009778.1 324986 325492 D KEGG: ssn:SSO_3206 2.0e-69 ygjF; hypothetical protein K03649; COG: COG3663 G:T/U mismatch-specific DNA glycosylase; Psort location: cytoplasmic, score: 23; G/U mismatch-specific DNA glycosylase 324986..325492 Cronobacter sakazakii ATCC BAA-894 5549586 YP_001436488.1 CDS ESA_00354 NC_009778.1 325545 325967 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(325545..325967) Cronobacter sakazakii ATCC BAA-894 5549661 YP_001436489.1 CDS ESA_00355 NC_009778.1 326210 328054 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(326210..328054) Cronobacter sakazakii ATCC BAA-894 5549723 YP_001436490.1 CDS dnaG NC_009778.1 328294 330039 R synthesizes RNA primers at the replication forks; DNA primase complement(328294..330039) Cronobacter sakazakii ATCC BAA-894 5549525 YP_001436491.1 CDS ESA_00356 NC_009778.1 329839 330147 D Psort location: mitochondrial, score: 23; hypothetical protein 329839..330147 Cronobacter sakazakii ATCC BAA-894 5550227 YP_001436492.1 CDS ESA_00358 NC_009778.1 330616 331629 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 330616..331629 Cronobacter sakazakii ATCC BAA-894 5549670 YP_001436493.1 CDS ESA_00359 NC_009778.1 331666 332283 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY complement(331666..332283) Cronobacter sakazakii ATCC BAA-894 5549915 YP_001436494.1 CDS ESA_00360 NC_009778.1 332304 332750 D KEGG: spt:SPA3074 5.2e-48 folB; dihydroneopterin aldolase K01633; COG: COG1539 Dihydroneopterin aldolase; Psort location: cytoplasmic, score: 23; hypothetical protein 332304..332750 Cronobacter sakazakii ATCC BAA-894 5549937 YP_001436495.1 CDS ESA_00361 NC_009778.1 332878 333696 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 332878..333696 Cronobacter sakazakii ATCC BAA-894 5549898 YP_001436496.1 CDS cca NC_009778.1 333702 334949 R catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase complement(333702..334949) Cronobacter sakazakii ATCC BAA-894 5552244 YP_001436497.1 CDS ESA_00363 NC_009778.1 335045 335659 R KEGG: lmf:LMOf2365_1540 0.00028 ami; N-acetylmuramoyl-L-alanine amidase, family 3 K01448; COG: COG3103 SH3 domain protein; Psort location: endoplasmic reticulum, score: 9; putative signal transduction protein complement(335045..335659) Cronobacter sakazakii ATCC BAA-894 5550116 YP_001436498.1 CDS ESA_00364 NC_009778.1 335910 337211 D KEGG: aha:AHA_3770 2.2e-40 adenylate cyclase K01768; COG: COG3025 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 335910..337211 Cronobacter sakazakii ATCC BAA-894 5549554 YP_001436499.1 CDS ESA_00365 NC_009778.1 337231 340068 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 337231..340068 Cronobacter sakazakii ATCC BAA-894 5549909 YP_001436500.1 CDS ESA_00366 NC_009778.1 340136 341563 D catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 340136..341563 Cronobacter sakazakii ATCC BAA-894 5549934 YP_001436501.1 CDS ESA_00367 NC_009778.1 341614 341979 R KEGG: cme:CMA103C 0.00053 Raf-related MAP kinase kinase kinase (MAP3K), theta-type K00870; COG: COG2960 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(341614..341979) Cronobacter sakazakii ATCC BAA-894 5549623 YP_001436502.1 CDS ribB NC_009778.1 342394 343047 D DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 342394..343047 Cronobacter sakazakii ATCC BAA-894 5549547 YP_001436503.1 CDS ESA_00369 NC_009778.1 343114 343920 R KEGG: rxy:Rxyl_0125 0.0023 NADH dehydrogenase (quinone) K05903; COG: COG0428 Predicted divalent heavy-metal cations transporter; Psort location: endoplasmic reticulum, score: 9; zinc transporter ZupT complement(343114..343920) Cronobacter sakazakii ATCC BAA-894 5550125 YP_001436504.1 CDS ESA_00370 NC_009778.1 343995 344873 D seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 343995..344873 Cronobacter sakazakii ATCC BAA-894 5550152 YP_001436505.1 CDS ESA_00371 NC_009778.1 344901 346061 R KEGG: vvy:VV2267 2.7e-122 glutaTHIonylspermidine synthase K01917; COG: COG0754 GlutaTHIonylspermidine synthase; Psort location: cytoskeletal, score: 9; hypothetical protein complement(344901..346061) Cronobacter sakazakii ATCC BAA-894 5549761 YP_001436506.1 CDS ESA_00372 NC_009778.1 346065 346718 R COG: COG5463 Predicted integral membrane protein; Psort location: nuclear, score: 23; hypothetical protein complement(346065..346718) Cronobacter sakazakii ATCC BAA-894 5549847 YP_001436507.1 CDS tolC NC_009778.1 346869 348362 R trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein complement(346869..348362) Cronobacter sakazakii ATCC BAA-894 5549699 YP_001436508.1 CDS nudF NC_009778.1 348570 349202 D ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 348570..349202 Cronobacter sakazakii ATCC BAA-894 5550177 YP_001436509.1 CDS ESA_00375 NC_009778.1 349235 349627 D COG: COG3151 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 349235..349627 Cronobacter sakazakii ATCC BAA-894 5549834 YP_001436510.1 CDS ESA_00376 NC_009778.1 349652 350479 D KEGG: eci:UTI89_C3466 7.4e-120 icc; icc protein K03651; COG: COG1409 Predicted phosphohydrolases; Psort location: cytoplasmic, score: 23; cyclic 3',5'-adenosine monophosphate phosphodiesterase 349652..350479 Cronobacter sakazakii ATCC BAA-894 5549510 YP_001436511.1 CDS ESA_00377 NC_009778.1 350479 351054 D Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 350479..351054 Cronobacter sakazakii ATCC BAA-894 5550299 YP_001436512.1 CDS ESA_00378 NC_009778.1 351097 352989 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 351097..352989 Cronobacter sakazakii ATCC BAA-894 5549702 YP_001436513.1 CDS ESA_00379 NC_009778.1 353311 355491 D KEGG: sec:SC3998 0. katG; catalase; hydroperoxidase HPI(I) K03782; COG: COG0376 Catalase (peroxidase I); Psort location: cytoplasmic, score: 23; hypothetical protein 353311..355491 Cronobacter sakazakii ATCC BAA-894 5550203 YP_001436514.1 CDS ESA_00380 NC_009778.1 355555 355869 R COG: COG1359 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(355555..355869) Cronobacter sakazakii ATCC BAA-894 5549838 YP_001436515.1 CDS ESA_00381 NC_009778.1 355901 356512 R KEGG: eci:UTI89_C3455 4.3e-92 mdaB; modulator of drug activity B K03923; COG: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); Psort location: cytoplasmic, score: 23; hypothetical protein complement(355901..356512) Cronobacter sakazakii ATCC BAA-894 5550281 YP_001436516.1 CDS ESA_00382 NC_009778.1 356682 358952 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 356682..358952 Cronobacter sakazakii ATCC BAA-894 5549451 YP_001436517.1 CDS ESA_00383 NC_009778.1 359192 359929 D KEGG: eco:b3018 7.5e-111 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 359192..359929 Cronobacter sakazakii ATCC BAA-894 5552482 YP_001436518.1 CDS ESA_00384 NC_009778.1 359977 361389 D KEGG: eci:UTI89_C3443 1.1e-228 sufI; FtsI suppressor K04753; COG: COG2132 Putative multicopper oxidases; Psort location: mitochondrial, score: 23; repressor protein for FtsI 359977..361389 Cronobacter sakazakii ATCC BAA-894 5552266 YP_001436519.1 CDS ESA_00385 NC_009778.1 361774 362910 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(361774..362910) Cronobacter sakazakii ATCC BAA-894 5552429 YP_001436520.1 CDS ESA_00386 NC_009778.1 362903 363496 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase complement(362903..363496) Cronobacter sakazakii ATCC BAA-894 5550298 YP_001436521.1 CDS ESA_00387 NC_009778.1 363511 363801 R KEGG: lma:LmjF04.1190 0.0098 tRNA nucleotidyltransferase, putative; COG: COG1872 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(363511..363801) Cronobacter sakazakii ATCC BAA-894 5550175 YP_001436522.1 CDS ESA_00388 NC_009778.1 363798 364352 R COG: COG0762 Predicted integral membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(363798..364352) Cronobacter sakazakii ATCC BAA-894 5550192 YP_001436523.1 CDS ESA_00389 NC_009778.1 364374 365081 R KEGG: eci:UTI89_C3340 3.2e-96 yggS; hypothetical protein; COG: COG0325 Predicted enzyme with a TIM-barrel fold; Psort location: cytoplasmic, score: 23; hypothetical protein complement(364374..365081) Cronobacter sakazakii ATCC BAA-894 5549883 YP_001436524.1 CDS ESA_00390 NC_009778.1 365097 366113 D KEGG: pen:PSEEN2333 3.6e-33 xcpR-2; type II secretion pathway protein E K01509; COG: COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT; Psort location: cytoplasmic, score: 23; hypothetical protein 365097..366113 Cronobacter sakazakii ATCC BAA-894 5549808 YP_001436525.1 CDS ESA_00391 NC_009778.1 366110 368368 R KEGG: atc:AGR_L_1103 3.4e-05 sarcosine oxidase alpha subunit K00302; COG: NOG08355 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(366110..368368) Cronobacter sakazakii ATCC BAA-894 5549867 YP_001436526.1 CDS ESA_00392 NC_009778.1 368413 369123 D COG: COG1414 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 368413..369123 Cronobacter sakazakii ATCC BAA-894 5549292 YP_001436527.1 CDS ESA_00393 NC_009778.1 369283 369699 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(369283..369699) Cronobacter sakazakii ATCC BAA-894 5549807 YP_001436528.1 CDS ESA_00394 NC_009778.1 369699 370262 R COG: COG1678 Putative transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(369699..370262) Cronobacter sakazakii ATCC BAA-894 5549893 YP_001436529.1 CDS ESA_00395 NC_009778.1 370376 371323 R catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase complement(370376..371323) Cronobacter sakazakii ATCC BAA-894 5549704 YP_001436530.1 CDS ESA_00396 NC_009778.1 371336 372073 R COG: COG1385 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(371336..372073) Cronobacter sakazakii ATCC BAA-894 5549765 YP_001436531.1 CDS ESA_00397 NC_009778.1 372141 372848 R KEGG: eco:b2945 1.7e-106 endA; DNA-specific endonuclease I K01150; COG: COG2356 Endonuclease I; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(372141..372848) Cronobacter sakazakii ATCC BAA-894 5549654 YP_001436532.1 CDS ESA_00398 NC_009778.1 372937 373437 R COG: COG3091 Uncharacterized protein conserved in bacteria; Psort location: mitochondrial, score: 23; hypothetical protein complement(372937..373437) Cronobacter sakazakii ATCC BAA-894 5549790 YP_001436533.1 CDS ESA_00399 NC_009778.1 373528 374922 R KEGG: cal:orf19.3526 9.8e-54 ITR2; myo-inositol transporter K08140; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(373528..374922) Cronobacter sakazakii ATCC BAA-894 5549904 YP_001436534.1 CDS ESA_00400 NC_009778.1 375336 376490 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(375336..376490) Cronobacter sakazakii ATCC BAA-894 5549819 YP_001436535.1 CDS ESA_00401 NC_009778.1 376940 377077 D Psort location: mitochondrial, score: 23; hypothetical protein 376940..377077 Cronobacter sakazakii ATCC BAA-894 5549995 YP_001436536.1 CDS ESA_00402 NC_009778.1 377347 379260 D catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 377347..379260 Cronobacter sakazakii ATCC BAA-894 5550130 YP_001436537.1 CDS ESA_00403 NC_009778.1 379484 380404 D catalyzes the formation of putrescine from agmatine; agmatinase 379484..380404 Cronobacter sakazakii ATCC BAA-894 5549598 YP_001436538.1 CDS ESA_00404 NC_009778.1 379541 380473 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(379541..380473) Cronobacter sakazakii ATCC BAA-894 5549771 YP_001436539.1 CDS ESA_00405 NC_009778.1 380518 381309 R KEGG: stt:t2997 7.3e-113 putative metalloprotease K07387; COG: COG0501 Zn-dependent protease with chaperone function; Psort location: nuclear, score: 23; hypothetical protein complement(380518..381309) Cronobacter sakazakii ATCC BAA-894 5549775 YP_001436540.1 CDS ESA_00406 NC_009778.1 381557 383548 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 381557..383548 Cronobacter sakazakii ATCC BAA-894 5549540 YP_001436541.1 CDS ESA_00407 NC_009778.1 383604 384740 R KEGG: azo:azo2644 7.7e-86 draG2; putative ADP-ribosyl-[dinitrogen reductase] hydrolase; COG: COG1397 ADP-ribosylglycohydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(383604..384740) Cronobacter sakazakii ATCC BAA-894 5550135 YP_001436542.1 CDS ESA_00408 NC_009778.1 385094 386113 D NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 385094..386113 Cronobacter sakazakii ATCC BAA-894 5549584 YP_001436543.1 CDS pgk NC_009778.1 386190 387353 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 386190..387353 Cronobacter sakazakii ATCC BAA-894 5549475 YP_001436544.1 CDS ESA_00410 NC_009778.1 387450 388526 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 387450..388526 Cronobacter sakazakii ATCC BAA-894 5552352 YP_001436545.1 CDS ESA_00411 NC_009778.1 388717 389655 D participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 388717..389655 Cronobacter sakazakii ATCC BAA-894 5550194 YP_001436546.1 CDS ESA_00412 NC_009778.1 389844 390437 D Involved in the export of arginine; arginine exporter protein 389844..390437 Cronobacter sakazakii ATCC BAA-894 5549977 YP_001436547.1 CDS ESA_00413 NC_009778.1 390557 391339 D COG: COG2968 Uncharacterized conserved protein; Psort location: nuclear, score: 23; hypothetical protein 390557..391339 Cronobacter sakazakii ATCC BAA-894 5549644 YP_001436548.1 CDS ESA_00414 NC_009778.1 391368 392261 R specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein complement(391368..392261) Cronobacter sakazakii ATCC BAA-894 5549483 YP_001436549.1 CDS ESA_00415 NC_009778.1 392393 393088 D KEGG: ecc:c3495 8.0e-107 rpiA; ribose 5-phosphate isomerase A K01807; COG: COG0120 Ribose 5-phosphate isomerase; Psort location: cytoplasmic, score: 23; hypothetical protein 392393..393088 Cronobacter sakazakii ATCC BAA-894 5549493 YP_001436550.1 CDS ESA_00416 NC_009778.1 393358 394596 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 393358..394596 Cronobacter sakazakii ATCC BAA-894 5549497 YP_001436551.1 CDS ESA_00418 NC_009778.1 395521 395850 R KEGG: shn:Shewana3_3505 8.5e-16 fructose-bisphosphatase K01086; COG: COG3027 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; Z-ring-associated protein complement(395521..395850) Cronobacter sakazakii ATCC BAA-894 5549524 YP_001436552.1 CDS ESA_00419 NC_009778.1 396006 396590 D the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 396006..396590 Cronobacter sakazakii ATCC BAA-894 5549718 YP_001436553.1 CDS ESA_00420 NC_009778.1 396614 397930 D exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 396614..397930 Cronobacter sakazakii ATCC BAA-894 5549630 YP_001436554.1 CDS ESA_00421 NC_009778.1 397927 399105 D Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 397927..399105 Cronobacter sakazakii ATCC BAA-894 5549840 YP_001436555.1 CDS ESA_00422 NC_009778.1 399152 400318 D KEGG: ssn:SSO_3059 3.1e-176 visC; hypothetical protein; COG: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; Psort location: cytoplasmic, score: 23; hypothetical protein 399152..400318 Cronobacter sakazakii ATCC BAA-894 5549791 YP_001436556.1 CDS ESA_00423 NC_009778.1 400540 400683 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(400540..400683) Cronobacter sakazakii ATCC BAA-894 5550159 YP_001436557.1 CDS gcvT NC_009778.1 400741 401838 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 400741..401838 Cronobacter sakazakii ATCC BAA-894 5550277 YP_001436558.1 CDS ESA_00425 NC_009778.1 401862 402251 D part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 401862..402251 Cronobacter sakazakii ATCC BAA-894 5550260 YP_001436559.1 CDS ESA_00427 NC_009778.1 402253 402435 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(402253..402435) Cronobacter sakazakii ATCC BAA-894 5552263 YP_001436560.1 CDS ESA_00426 NC_009778.1 402382 405255 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 402382..405255 Cronobacter sakazakii ATCC BAA-894 5549571 YP_001436561.1 CDS ESA_00428 NC_009778.1 405369 406166 D KEGG: sfx:S3087 7.6e-102 ygfF; putative oxidoreductase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 405369..406166 Cronobacter sakazakii ATCC BAA-894 5550253 YP_001436562.1 CDS ESA_00429 NC_009778.1 406454 407887 R KEGG: ecp:ECP_2895 1.6e-252 6-phospho-beta-glucosidase BglA K01223; COG: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(406454..407887) Cronobacter sakazakii ATCC BAA-894 5549628 YP_001436563.1 CDS ESA_00430 NC_009778.1 408039 408767 R KEGG: bxe:Bxe_A3454 9.8e-09 glucokinase K00845; COG: COG1737 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(408039..408767) Cronobacter sakazakii ATCC BAA-894 5549562 YP_001436564.1 CDS ESA_00431 NC_009778.1 408944 409258 D COG: COG3097 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 408944..409258 Cronobacter sakazakii ATCC BAA-894 5549454 YP_001436565.1 CDS ESA_00432 NC_009778.1 409401 410054 D COG: COG1272 Predicted membrane protein, hemolysin III homolog; Psort location: plasma membrane, score: 23; hypothetical protein 409401..410054 Cronobacter sakazakii ATCC BAA-894 5549660 YP_001436566.1 CDS ESA_00433 NC_009778.1 410159 411148 R physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator complement(410159..411148) Cronobacter sakazakii ATCC BAA-894 5549519 YP_001436567.1 CDS ESA_00434 NC_009778.1 411474 411692 D COG: COG2938 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 411474..411692 Cronobacter sakazakii ATCC BAA-894 5549437 YP_001436568.1 CDS ESA_00435 NC_009778.1 411673 412089 D COG: NOG09016 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 411673..412089 Cronobacter sakazakii ATCC BAA-894 5549484 YP_001436569.1 CDS ESA_00436 NC_009778.1 412103 412624 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB complement(412103..412624) Cronobacter sakazakii ATCC BAA-894 5549606 YP_001436570.1 CDS xerD NC_009778.1 412663 413622 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 412663..413622 Cronobacter sakazakii ATCC BAA-894 5549828 YP_001436571.1 CDS ESA_00438 NC_009778.1 413645 414364 D DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 413645..414364 Cronobacter sakazakii ATCC BAA-894 5549821 YP_001436572.1 CDS ESA_00439 NC_009778.1 414470 416101 D 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 414470..416101 Cronobacter sakazakii ATCC BAA-894 5549727 YP_001436573.1 CDS ESA_00440 NC_009778.1 416098 416229 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(416098..416229) Cronobacter sakazakii ATCC BAA-894 5549804 YP_001436574.1 CDS ESA_00441 NC_009778.1 416415 417296 D KEGG: reh:H16_A1169 1.3e-106 prfB; protein chain release factor B (RF-2); COG: COG1186 Protein chain release factor B; Psort location: cytoskeletal, score: 9; hypothetical protein 416415..417296 Cronobacter sakazakii ATCC BAA-894 5550076 YP_001436575.1 CDS lysS NC_009778.1 417306 418823 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 417306..418823 Cronobacter sakazakii ATCC BAA-894 5549825 YP_001436576.1 CDS ESA_00443 NC_009778.1 419374 419724 D KEGG: eci:UTI89_C3250 8.2e-50 ygeR; hypothetical lipoprotein YgeR precursor; COG: COG0739 Membrane proteins related to metalloendopeptidases; Psort location: nuclear, score: 23; hypothetical protein 419374..419724 Cronobacter sakazakii ATCC BAA-894 5549935 YP_001436577.1 CDS ESA_00445 NC_009778.1 420445 421065 D COG: COG1280 Putative threonine efflux protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 420445..421065 Cronobacter sakazakii ATCC BAA-894 5552460 YP_001436578.1 CDS ESA_00446 NC_009778.1 421187 421846 D COG: NOG26670 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 421187..421846 Cronobacter sakazakii ATCC BAA-894 5549922 YP_001436579.1 CDS ESA_00447 NC_009778.1 421998 423176 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 421998..423176 Cronobacter sakazakii ATCC BAA-894 5551677 YP_001436580.1 CDS ESA_00448 NC_009778.1 423539 424219 D COG: NOG06222 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 423539..424219 Cronobacter sakazakii ATCC BAA-894 5549914 YP_001436581.1 CDS ESA_00449 NC_009778.1 424460 425638 R KEGG: yps:YPTB2368 2.0e-151 ogl; oligogalacturonate lyase K01730; COG: COG0823 Periplasmic component of the Tol biopolymer transport system; Psort location: cytoplasmic, score: 23; hypothetical protein complement(424460..425638) Cronobacter sakazakii ATCC BAA-894 5549535 YP_001436582.1 CDS ESA_00451 NC_009778.1 425983 426111 R Psort location: nuclear, score: 23; hypothetical protein complement(425983..426111) Cronobacter sakazakii ATCC BAA-894 5549895 YP_001436583.1 CDS ESA_00450 NC_009778.1 425993 426097 D Psort location: cytoplasmic, score: 23; hypothetical protein 425993..426097 Cronobacter sakazakii ATCC BAA-894 5550202 YP_001436584.1 CDS ESA_00452 NC_009778.1 426249 427010 D catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 426249..427010 Cronobacter sakazakii ATCC BAA-894 5550208 YP_001436585.1 CDS ESA_00453 NC_009778.1 427232 428521 R KEGG: eci:UTI89_C1581 1.6e-06 ycjN; putative ABC transporter periplasmic binding protein YcjN precursor K02027; COG: COG1653 ABC-type sugar transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(427232..428521) Cronobacter sakazakii ATCC BAA-894 5549611 YP_001436586.1 CDS ESA_00454 NC_009778.1 428535 429236 R KEGG: yps:YPTB3446 8.3e-57 ABC sugar transporter, ATP-binding subunit K02028; COG: COG3839 ABC-type sugar transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(428535..429236) Cronobacter sakazakii ATCC BAA-894 5549665 YP_001436587.1 CDS ESA_00455 NC_009778.1 429212 429706 R KEGG: reh:H16_A2327 8.5e-48 ABC-type transporter, ATPase component: CUT1 family; COG: COG3839 ABC-type sugar transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(429212..429706) Cronobacter sakazakii ATCC BAA-894 5549714 YP_001436588.1 CDS ESA_00456 NC_009778.1 429719 430633 R COG: COG0395 ABC-type sugar transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(429719..430633) Cronobacter sakazakii ATCC BAA-894 5549458 YP_001436589.1 CDS ESA_00457 NC_009778.1 430626 431516 R KEGG: ava:Ava_0243 0.0036 molybdate ABC transporter, permease protein K02018; COG: COG1175 ABC-type sugar transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(430626..431516) Cronobacter sakazakii ATCC BAA-894 5549636 YP_001436590.1 CDS ESA_00458 NC_009778.1 431699 431851 D Psort location: mitochondrial, score: 23; hypothetical protein 431699..431851 Cronobacter sakazakii ATCC BAA-894 5552125 YP_001436591.1 CDS ESA_00459 NC_009778.1 432125 433267 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 432125..433267 Cronobacter sakazakii ATCC BAA-894 5549513 YP_001436592.1 CDS ESA_00460 NC_009778.1 433324 433680 R KEGG: nph:NP3568A 0.00015 homolog 3 to mannose-1-phosphate guanylyltransferase (GDP) K00971; COG: COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(433324..433680) Cronobacter sakazakii ATCC BAA-894 5550218 YP_001436593.1 CDS ESA_00461 NC_009778.1 433800 434501 D KEGG: eci:UTI89_C3244 3.1e-89 ygeA; hypothetical protein YgeA K01779; COG: COG1794 Aspartate racemase; Psort location: cytoplasmic, score: 23; hypothetical protein 433800..434501 Cronobacter sakazakii ATCC BAA-894 5550286 YP_001436594.1 CDS ESA_00462 NC_009778.1 434479 435417 R activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR complement(434479..435417) Cronobacter sakazakii ATCC BAA-894 5550186 YP_001436595.1 CDS ESA_00463 NC_009778.1 435721 436983 D catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 435721..436983 Cronobacter sakazakii ATCC BAA-894 5549755 YP_001436596.1 CDS ESA_00464 NC_009778.1 436960 438012 R KEGG: efa:EF1922 1.1e-10 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(436960..438012) Cronobacter sakazakii ATCC BAA-894 5550252 YP_001436597.1 CDS ESA_00465 NC_009778.1 438272 439609 D KEGG: bcz:BCZK4903 3.7e-70 celB; PTS system, cellobiose-specific IIC component K02761; COG: COG1455 Phosphotransferase system cellobiose-specific component IIC; Psort location: plasma membrane, score: 23; hypothetical protein 438272..439609 Cronobacter sakazakii ATCC BAA-894 5550295 YP_001436598.1 CDS ESA_00466 NC_009778.1 439602 441044 D KEGG: eca:ECA3646 4.3e-202 celH; putative 6-phospho-beta-glucosidase K05350; COG: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Psort location: cytoplasmic, score: 23; hypothetical protein 439602..441044 Cronobacter sakazakii ATCC BAA-894 5549680 YP_001436599.1 CDS ESA_00467 NC_009778.1 441087 441371 D KEGG: eca:ECA3645 5.0e-34 PTS system, lichenan-specific IIb component K02760; COG: COG1440 Phosphotransferase system cellobiose-specific component IIB; Psort location: cytoplasmic, score: 23; hypothetical protein 441087..441371 Cronobacter sakazakii ATCC BAA-894 5549464 YP_001436600.1 CDS ESA_00468 NC_009778.1 441433 442206 D KEGG: reh:H16_B1289 5.7e-08 phnF; regulator of phosphonate operon, GntR-family; COG: COG2186 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 441433..442206 Cronobacter sakazakii ATCC BAA-894 5550199 YP_001436601.1 CDS ESA_00469 NC_009778.1 442203 442679 D KEGG: reh:H16_B1278 0.00017 predicted acetyltransferase K00680; COG: NOG22247 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 442203..442679 Cronobacter sakazakii ATCC BAA-894 5552456 YP_001436602.1 CDS ESA_00470 NC_009778.1 442640 443656 R controls transcription of galETKM; DNA-binding transcriptional regulator GalR complement(442640..443656) Cronobacter sakazakii ATCC BAA-894 5552417 YP_001436603.1 CDS ESA_00472 NC_009778.1 444152 446311 D Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 444152..446311 Cronobacter sakazakii ATCC BAA-894 5550266 YP_001436604.1 CDS ESA_00473 NC_009778.1 446304 447497 D KEGG: pca:Pcar_2776 4.4e-23 2-acyl-glycerophospho-ethanolamine acyltransferase K05939:K01909; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; lysophospholipid transporter LplT 446304..447497 Cronobacter sakazakii ATCC BAA-894 5550184 YP_001436605.1 CDS tas NC_009778.1 447548 448528 R complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase complement(447548..448528) Cronobacter sakazakii ATCC BAA-894 5550233 YP_001436606.1 CDS ESA_00475 NC_009778.1 448650 448892 D Psort location: cytoplasmic, score: 23; hypothetical protein 448650..448892 Cronobacter sakazakii ATCC BAA-894 5550263 YP_001436607.1 CDS ESA_00476 NC_009778.1 448725 449018 R COG: NOG13901 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(448725..449018) Cronobacter sakazakii ATCC BAA-894 5552057 YP_001436608.1 CDS ESA_00477 NC_009778.1 449072 449785 R COG: COG0861 Membrane protein TerC, possibly involved in tellurium resistance; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(449072..449785) Cronobacter sakazakii ATCC BAA-894 5550234 YP_001436609.1 CDS ESA_00478 NC_009778.1 449864 450628 R MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein complement(449864..450628) Cronobacter sakazakii ATCC BAA-894 5552157 YP_001436610.1 CDS ESA_00479 NC_009778.1 451234 451767 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 451234..451767 Cronobacter sakazakii ATCC BAA-894 5552166 YP_001436611.1 CDS ESA_00480 NC_009778.1 451780 454026 D member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 451780..454026 Cronobacter sakazakii ATCC BAA-894 5552182 YP_001436612.1 CDS ESA_00481 NC_009778.1 454191 455066 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 454191..455066 Cronobacter sakazakii ATCC BAA-894 5552167 YP_001436613.1 CDS thyA NC_009778.1 455073 455867 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 455073..455867 Cronobacter sakazakii ATCC BAA-894 5552079 YP_001436614.1 CDS ESA_00483 NC_009778.1 456048 456521 D COG: COG2165 Type II secretory pathway, pseudopilin PulG; Psort location: mitochondrial, score: 23; hypothetical protein 456048..456521 Cronobacter sakazakii ATCC BAA-894 5551939 YP_001436615.1 CDS ESA_00484 NC_009778.1 456512 457075 D COG: COG4795 Type II secretory pathway, component PulJ; Psort location: mitochondrial, score: 23; hypothetical protein 456512..457075 Cronobacter sakazakii ATCC BAA-894 5552101 YP_001436616.1 CDS ESA_00485 NC_009778.1 457072 457494 D COG: NOG10274 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 457072..457494 Cronobacter sakazakii ATCC BAA-894 5552115 YP_001436617.1 CDS ESA_00486 NC_009778.1 457479 457811 D COG: COG4967 Tfp pilus assembly protein PilV; Psort location: cytoplasmic, score: 23; hypothetical protein 457479..457811 Cronobacter sakazakii ATCC BAA-894 5552113 YP_001436618.1 CDS recC NC_009778.1 457824 461195 D catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 457824..461195 Cronobacter sakazakii ATCC BAA-894 5552090 YP_001436619.1 CDS ESA_00488 NC_009778.1 461343 464189 D KEGG: sec:SC2933 0. ptr; protease III K01407; COG: COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; Psort location: cytoplasmic, score: 23; hypothetical protein 461343..464189 Cronobacter sakazakii ATCC BAA-894 5552118 YP_001436620.1 CDS recB NC_009778.1 464186 467728 D helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 464186..467728 Cronobacter sakazakii ATCC BAA-894 5551986 YP_001436621.1 CDS recD NC_009778.1 467725 469560 D helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 467725..469560 Cronobacter sakazakii ATCC BAA-894 5552477 YP_001436622.1 CDS ESA_00491 NC_009778.1 469597 470649 R catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase complement(469597..470649) Cronobacter sakazakii ATCC BAA-894 5552091 YP_001436623.1 CDS ESA_00492 NC_009778.1 470695 470946 D Psort location: cytoplasmic, score: 23; hypothetical protein 470695..470946 Cronobacter sakazakii ATCC BAA-894 5552036 YP_001436624.1 CDS ESA_00493 NC_009778.1 470964 471098 D Psort location: cytoplasmic, score: 23; hypothetical protein 470964..471098 Cronobacter sakazakii ATCC BAA-894 5552014 YP_001436625.1 CDS ESA_00494 NC_009778.1 471156 472409 D KEGG: sty:STY3129 3.8e-187 N-acetylmuramoyl-L-alanine amidase K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 471156..472409 Cronobacter sakazakii ATCC BAA-894 5552017 YP_001436626.1 CDS mltA NC_009778.1 472830 473993 D membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 472830..473993 Cronobacter sakazakii ATCC BAA-894 5552040 YP_001436627.1 CDS ESA_00498 NC_009778.1 474103 474912 D KEGG: cal:orf19.2115 4.3e-25 molybdopterin-converting factor; COG: COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and THIamine biosynthesis family 1; Psort location: cytoplasmic, score: 23; hypothetical protein 474103..474912 Cronobacter sakazakii ATCC BAA-894 5551987 YP_001436628.1 CDS ESA_00499 NC_009778.1 474913 475356 R KEGG: cps:CPS_2211 1.1e-16 putative selenocysteine lyase K02426; COG: COG2166 SufE protein probably involved in Fe-S center assembly; Psort location: cytoplasmic, score: 23; hypothetical protein complement(474913..475356) Cronobacter sakazakii ATCC BAA-894 5552048 YP_001436629.1 CDS ESA_00500 NC_009778.1 475357 476598 R KEGG: eco:b2810 2.9e-173 csdA, ygdJ; cysteine sulfinate desulfinase; COG: COG0520 Selenocysteine lyase; Psort location: cytoplasmic, score: 23; cysteine sulfinate desulfinase complement(475357..476598) Cronobacter sakazakii ATCC BAA-894 5552059 YP_001436630.1 CDS ESA_00501 NC_009778.1 476788 476982 D COG: NOG14132 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 476788..476982 Cronobacter sakazakii ATCC BAA-894 5551972 YP_001436631.1 CDS ESA_00503 NC_009778.1 477328 478245 D Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 477328..478245 Cronobacter sakazakii ATCC BAA-894 5551961 YP_001436632.1 CDS ESA_00504 NC_009778.1 478291 478686 D COG: COG2363 Uncharacterized small membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 478291..478686 Cronobacter sakazakii ATCC BAA-894 5552025 YP_001436633.1 CDS ESA_00505 NC_009778.1 478679 479779 D KEGG: vfi:VF0593 4.1e-126 methyltransferase; COG: COG2933 Predicted SAM-dependent methyltransferase; Psort location: cytoplasmic, score: 23; putative RNA 2'-O-ribose methyltransferase 478679..479779 Cronobacter sakazakii ATCC BAA-894 5551976 YP_001436634.1 CDS ESA_00506 NC_009778.1 480024 480779 R KEGG: ecs:ECs3658 2.1e-106 5'-3' exonuclease K01146; COG: COG0258 5-3 exonuclease (including N-terminal domain of PolI); Psort location: cytoplasmic, score: 23; hypothetical protein complement(480024..480779) Cronobacter sakazakii ATCC BAA-894 5552013 YP_001436635.1 CDS ESA_00507 NC_009778.1 480910 482289 R KEGG: sfl:SF2811 1.1e-221 sdaB; L-serine dehydratase (deaminase), L-SD2 K01752; COG: COG1760 L-serine deaminase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(480910..482289) Cronobacter sakazakii ATCC BAA-894 5552176 YP_001436636.1 CDS ESA_00509 NC_009778.1 482344 483630 R COG: COG0814 Amino acid permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(482344..483630) Cronobacter sakazakii ATCC BAA-894 5551978 YP_001436637.1 CDS ESA_00508 NC_009778.1 482416 483672 D Psort location: nuclear, score: 23; hypothetical protein 482416..483672 Cronobacter sakazakii ATCC BAA-894 5551963 YP_001436638.1 CDS ESA_00510 NC_009778.1 484081 485415 R KEGG: hch:HCH_00651 3.4e-131 predicted Rossmann fold nucleotide-binding protein K00052; COG: COG1611 Predicted Rossmann fold nucleotide-binding protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(484081..485415) Cronobacter sakazakii ATCC BAA-894 5551930 YP_001436639.1 CDS queF NC_009778.1 485563 486408 R catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(485563..486408) Cronobacter sakazakii ATCC BAA-894 5551957 YP_001436640.1 CDS ESA_00512 NC_009778.1 486478 487023 D putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 486478..487023 Cronobacter sakazakii ATCC BAA-894 5551967 YP_001436641.1 CDS ESA_00514 NC_009778.1 487665 487994 D KEGG: shn:Shewana3_2825 2.7e-12 dTDP-4-dehydrorhamnose 3,5-epimerase K01790; COG: COG3098 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 487665..487994 Cronobacter sakazakii ATCC BAA-894 5551977 YP_001436642.1 CDS ESA_00515 NC_009778.1 487991 488788 D catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 487991..488788 Cronobacter sakazakii ATCC BAA-894 5551952 YP_001436643.1 CDS ESA_00516 NC_009778.1 488792 489241 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 488792..489241 Cronobacter sakazakii ATCC BAA-894 5551936 YP_001436644.1 CDS ESA_00517 NC_009778.1 489276 492035 R part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA complement(489276..492035) Cronobacter sakazakii ATCC BAA-894 5551915 YP_001436645.1 CDS rumA NC_009778.1 492093 493391 D in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 492093..493391 Cronobacter sakazakii ATCC BAA-894 5551945 YP_001436646.1 CDS relA NC_009778.1 493443 495677 D (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 493443..495677 Cronobacter sakazakii ATCC BAA-894 5551928 YP_001436647.1 CDS mazG NC_009778.1 495778 496569 D functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 495778..496569 Cronobacter sakazakii ATCC BAA-894 5551866 YP_001436648.1 CDS ESA_00522 NC_009778.1 496756 498372 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(496756..498372) Cronobacter sakazakii ATCC BAA-894 5551934 YP_001436649.1 CDS pyrG NC_009778.1 496795 498432 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 496795..498432 Cronobacter sakazakii ATCC BAA-894 5550311 YP_001436650.1 CDS eno NC_009778.1 498515 499813 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 498515..499813 Cronobacter sakazakii ATCC BAA-894 5551913 YP_001436651.1 CDS ESA_00524 NC_009778.1 498629 499858 R COG: NOG13748 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(498629..499858) Cronobacter sakazakii ATCC BAA-894 5551890 YP_001436652.1 CDS ESA_00525 NC_009778.1 499864 500973 R KEGG: azo:azo3173 5.3e-18 galE1; UDP-glucose 4-epimerase K01784; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(499864..500973) Cronobacter sakazakii ATCC BAA-894 5551898 YP_001436653.1 CDS ESA_00526 NC_009778.1 501160 501339 D Psort location: cytoplasmic, score: 23; hypothetical protein 501160..501339 Cronobacter sakazakii ATCC BAA-894 5551916 YP_001436654.1 CDS ESA_00527 NC_009778.1 501296 502123 R KEGG: bte:BTH_I1550 5.1e-29 glucokinase/transcriptional regulator, RpiR family, fusion K00845; COG: COG1737 Transcriptional regulators; Psort location: vesicles of secretory system, score: 23; hypothetical protein complement(501296..502123) Cronobacter sakazakii ATCC BAA-894 5551817 YP_001436655.1 CDS ESA_00528 NC_009778.1 502294 503847 D KEGG: bcl:ABC0713 6.2e-203 PTS system, glucose-specific enzyme II, ABC component K02790:K02791; COG: COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; Psort location: plasma membrane, score: 23; hypothetical protein 502294..503847 Cronobacter sakazakii ATCC BAA-894 5551882 YP_001436656.1 CDS ESA_00529 NC_009778.1 503856 504545 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 503856..504545 Cronobacter sakazakii ATCC BAA-894 5551902 YP_001436657.1 CDS ESA_00530 NC_009778.1 504531 505544 R COG: COG1512 Beta-propeller domains of methanol dehydrogenase type; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(504531..505544) Cronobacter sakazakii ATCC BAA-894 5551905 YP_001436658.1 CDS ESA_00531 NC_009778.1 505698 506369 D KEGG: hpa:HPAG1_0914 3.5e-07 hypothetical protein K04071; COG: COG0602 Organic radical activating enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 505698..506369 Cronobacter sakazakii ATCC BAA-894 5551868 YP_001436659.1 CDS ESA_00532 NC_009778.1 506683 507045 R KEGG: sfl:SF2781 1.5e-59 ygcM; putative 6-pyruvoyl tetrahydrobiopterin synthase K01737; COG: COG0720 6-pyruvoyl-tetrahydropterin synthase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(506683..507045) Cronobacter sakazakii ATCC BAA-894 5551824 YP_001436660.1 CDS ESA_00534 NC_009778.1 507226 507351 R Psort location: mitochondrial, score: 23; hypothetical protein complement(507226..507351) Cronobacter sakazakii ATCC BAA-894 5551829 YP_001436661.1 CDS cysJ NC_009778.1 507350 509152 D catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 507350..509152 Cronobacter sakazakii ATCC BAA-894 5551773 YP_001436662.1 CDS ESA_00535 NC_009778.1 509152 510864 D hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 509152..510864 Cronobacter sakazakii ATCC BAA-894 5551850 YP_001436663.1 CDS ESA_00536 NC_009778.1 511022 511756 D catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 511022..511756 Cronobacter sakazakii ATCC BAA-894 5551840 YP_001436664.1 CDS ESA_00537 NC_009778.1 511788 512777 R catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase complement(511788..512777) Cronobacter sakazakii ATCC BAA-894 5551838 YP_001436665.1 CDS ESA_00538 NC_009778.1 513022 514437 D KEGG: eca:ECA3544 7.3e-168 cysG1; siroheme synthase [includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase] K02302:K02303:K02304; COG: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Psort location: cytoplasmic, score: 23; hypothetical protein 513022..514437 Cronobacter sakazakii ATCC BAA-894 5551809 YP_001436666.1 CDS ESA_00539 NC_009778.1 514447 515355 D with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 514447..515355 Cronobacter sakazakii ATCC BAA-894 5551816 YP_001436667.1 CDS cysN NC_009778.1 515365 516792 D may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 515365..516792 Cronobacter sakazakii ATCC BAA-894 5551791 YP_001436668.1 CDS ESA_00541 NC_009778.1 516792 517397 D converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 516792..517397 Cronobacter sakazakii ATCC BAA-894 5551843 YP_001436669.1 CDS ESA_00542 NC_009778.1 517447 517770 D COG: NOG12170 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 517447..517770 Cronobacter sakazakii ATCC BAA-894 5549004 YP_001436670.1 CDS ftsB NC_009778.1 517933 518244 D forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 517933..518244 Cronobacter sakazakii ATCC BAA-894 5551811 YP_001436671.1 CDS ispD NC_009778.1 518264 518974 D 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 518264..518974 Cronobacter sakazakii ATCC BAA-894 5551804 YP_001436672.1 CDS ispF NC_009778.1 518974 519453 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 518974..519453 Cronobacter sakazakii ATCC BAA-894 5551785 YP_001436673.1 CDS truD NC_009778.1 519450 520499 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 519450..520499 Cronobacter sakazakii ATCC BAA-894 5551742 YP_001436674.1 CDS surE NC_009778.1 520880 521641 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 520880..521641 Cronobacter sakazakii ATCC BAA-894 5551718 YP_001436675.1 CDS pcm NC_009778.1 521635 522261 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 521635..522261 Cronobacter sakazakii ATCC BAA-894 5551806 YP_001436676.1 CDS nlpD NC_009778.1 522560 523528 D outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 522560..523528 Cronobacter sakazakii ATCC BAA-894 5551766 YP_001436677.1 CDS ESA_00551 NC_009778.1 524635 525009 R COG: COG4460 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(524635..525009) Cronobacter sakazakii ATCC BAA-894 5551721 YP_001436678.1 CDS ESA_00552 NC_009778.1 525009 526388 R KEGG: sgl:SG1466 2.1e-08 dethiobiotinsynthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(525009..526388) Cronobacter sakazakii ATCC BAA-894 5551761 YP_001436679.1 CDS ESA_00553 NC_009778.1 526497 527402 D COG: COG0583 Transcriptional regulator; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 526497..527402 Cronobacter sakazakii ATCC BAA-894 5551750 YP_001436680.1 CDS ESA_00554 NC_009778.1 527405 527815 R COG: COG1846 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(527405..527815) Cronobacter sakazakii ATCC BAA-894 5551727 YP_001436681.1 CDS ESA_00555 NC_009778.1 527987 528604 D KEGG: sdy:SDY_2938 1.2e-82 phenylacrylic acid decarboxylase-like protein K03186; COG: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; Psort location: cytoplasmic, score: 23; hypothetical protein 527987..528604 Cronobacter sakazakii ATCC BAA-894 5551748 YP_001436682.1 CDS ESA_00556 NC_009778.1 528594 530024 D KEGG: gvi:gll3010 3.2e-55 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD K03182; COG: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Psort location: cytoplasmic, score: 23; hypothetical protein 528594..530024 Cronobacter sakazakii ATCC BAA-894 5551746 YP_001436683.1 CDS ESA_00557 NC_009778.1 530034 530270 D COG: NOG14130 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 530034..530270 Cronobacter sakazakii ATCC BAA-894 5551726 YP_001436684.1 CDS ESA_00558 NC_009778.1 530514 533075 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(530514..533075) Cronobacter sakazakii ATCC BAA-894 5551745 YP_001436685.1 CDS ESA_00559 NC_009778.1 533326 534030 R KEGG: bme:BMEII0002 1.9e-41 ribosomal-protein-serine acetyltransferase K00680; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(533326..534030) Cronobacter sakazakii ATCC BAA-894 5552431 YP_001436686.1 CDS ESA_00560 NC_009778.1 534238 535905 D KEGG: ret:RHE_PF00265 4.1e-05 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 534238..535905 Cronobacter sakazakii ATCC BAA-894 5551728 YP_001436687.1 CDS ESA_00561 NC_009778.1 535972 536118 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(535972..536118) Cronobacter sakazakii ATCC BAA-894 5551736 YP_001436688.1 CDS ESA_00562 NC_009778.1 536342 537124 D KEGG: bur:Bcep18194_A4695 1.5e-27 ABC polar amino acid transporter, periplasmic ligand binding protein K01713; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: extracellular, including cell wall, score: 23; hypothetical protein 536342..537124 Cronobacter sakazakii ATCC BAA-894 5552418 YP_001436689.1 CDS ESA_00563 NC_009778.1 537192 537962 D KEGG: sma:SAV6546 5.7e-26 putative ABC transporter permease K02028; COG: COG0765 ABC-type amino acid transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 537192..537962 Cronobacter sakazakii ATCC BAA-894 5551731 YP_001436690.1 CDS ESA_00564 NC_009778.1 537949 538671 D KEGG: eca:ECA3539 5.7e-97 amino acid ABC transporter, ATP-binding protein K02028; COG: COG1126 ABC-type polar amino acid transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 537949..538671 Cronobacter sakazakii ATCC BAA-894 5552487 YP_001436691.1 CDS ESA_00565 NC_009778.1 538787 539869 D membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 538787..539869 Cronobacter sakazakii ATCC BAA-894 5551743 YP_001436692.1 CDS ESA_00566 NC_009778.1 539977 540507 D COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Psort location: cytoplasmic, score: 23; competence damage-inducible protein A 539977..540507 Cronobacter sakazakii ATCC BAA-894 5551715 YP_001436693.1 CDS recA NC_009778.1 540596 541660 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 540596..541660 Cronobacter sakazakii ATCC BAA-894 5551725 YP_001436694.1 CDS recX NC_009778.1 541730 542227 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 541730..542227 Cronobacter sakazakii ATCC BAA-894 5551724 YP_001436695.1 CDS ESA_00570 NC_009778.1 542291 542425 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(542291..542425) Cronobacter sakazakii ATCC BAA-894 5551706 YP_001436696.1 CDS alaS NC_009778.1 542363 544990 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 542363..544990 Cronobacter sakazakii ATCC BAA-894 5551612 YP_001436697.1 CDS ESA_00571 NC_009778.1 545234 545419 D affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 545234..545419 Cronobacter sakazakii ATCC BAA-894 5551697 YP_001436698.1 CDS ESA_00577 NC_009778.1 546778 547347 D YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 546778..547347 Cronobacter sakazakii ATCC BAA-894 5551669 YP_001436699.1 CDS ESA_00578 NC_009778.1 547344 547772 D COG: COG1238 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 547344..547772 Cronobacter sakazakii ATCC BAA-894 5551652 YP_001436700.1 CDS ESA_00579 NC_009778.1 547865 549421 D involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 547865..549421 Cronobacter sakazakii ATCC BAA-894 5551644 YP_001436701.1 CDS ESA_00581 NC_009778.1 549574 550089 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 549574..550089 Cronobacter sakazakii ATCC BAA-894 5551667 YP_001436702.1 CDS ESA_00582 NC_009778.1 550529 553048 D KEGG: shn:Shewana3_3829 2.4e-87 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2199 FOG: GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 550529..553048 Cronobacter sakazakii ATCC BAA-894 5551626 YP_001436703.1 CDS ESA_00583 NC_009778.1 553098 554636 R KEGG: sgl:SG1466 2.6e-06 dethiobiotinsynthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(553098..554636) Cronobacter sakazakii ATCC BAA-894 5551649 YP_001436704.1 CDS ESA_00584 NC_009778.1 554651 555826 R COG: COG1566 Multidrug resistance efflux pump; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(554651..555826) Cronobacter sakazakii ATCC BAA-894 5551637 YP_001436705.1 CDS ESA_00585 NC_009778.1 555966 556496 R DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA complement(555966..556496) Cronobacter sakazakii ATCC BAA-894 5551624 YP_001436706.1 CDS ESA_00586 NC_009778.1 557034 558218 R KEGG: shn:Shewana3_1692 5.5e-16 Xaa-His dipeptidase K01270; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(557034..558218) Cronobacter sakazakii ATCC BAA-894 5551564 YP_001436707.1 CDS proX NC_009778.1 558475 559470 R with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit complement(558475..559470) Cronobacter sakazakii ATCC BAA-894 5549435 YP_001436708.1 CDS ESA_00588 NC_009778.1 559525 560595 R with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein complement(559525..560595) Cronobacter sakazakii ATCC BAA-894 5551613 YP_001436709.1 CDS ESA_00589 NC_009778.1 560588 561790 R KEGG: ecc:c3230 7.3e-184 proV; glycine betaine/L-proline transport ATP-binding protein proV K02000; COG: COG4175 ABC-type proline/glycine betaine transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(560588..561790) Cronobacter sakazakii ATCC BAA-894 5551574 YP_001436710.1 CDS nrdF NC_009778.1 562145 563107 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(562145..563107) Cronobacter sakazakii ATCC BAA-894 5551609 YP_001436711.1 CDS ESA_00591 NC_009778.1 563117 565237 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(563117..565237) Cronobacter sakazakii ATCC BAA-894 5552314 YP_001436712.1 CDS nrdI NC_009778.1 565249 565650 R in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein complement(565249..565650) Cronobacter sakazakii ATCC BAA-894 5551570 YP_001436713.1 CDS ESA_00594 NC_009778.1 565647 565892 R KEGG: eci:UTI89_C4152 0.0010 grxC; glutaredoxin 3 K03676; COG: COG0695 Glutaredoxin and related proteins; Psort location: nuclear, score: 23; glutaredoxin-like protein complement(565647..565892) Cronobacter sakazakii ATCC BAA-894 5551608 YP_001436714.1 CDS ESA_00593 NC_009778.1 565891 566181 D Psort location: mitochondrial, score: 23; hypothetical protein 565891..566181 Cronobacter sakazakii ATCC BAA-894 5551555 YP_001436715.1 CDS ESA_00595 NC_009778.1 566168 566494 R COG: COG4575 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(566168..566494) Cronobacter sakazakii ATCC BAA-894 5549429 YP_001436716.1 CDS ESA_00596 NC_009778.1 566655 566999 D COG: NOG09772 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 566655..566999 Cronobacter sakazakii ATCC BAA-894 5551579 YP_001436717.1 CDS ESA_00597 NC_009778.1 567011 567487 R COG: NOG11269 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(567011..567487) Cronobacter sakazakii ATCC BAA-894 5551594 YP_001436718.1 CDS ESA_00598 NC_009778.1 567532 567690 D Psort location: cytoplasmic, score: 23; hypothetical protein 567532..567690 Cronobacter sakazakii ATCC BAA-894 5549421 YP_001436719.1 CDS ESA_00599 NC_009778.1 567642 567833 D Psort location: mitochondrial, score: 23; hypothetical protein 567642..567833 Cronobacter sakazakii ATCC BAA-894 5551566 YP_001436720.1 CDS ESA_00600 NC_009778.1 567981 568289 D Psort location: cytoplasmic, score: 23; hypothetical protein 567981..568289 Cronobacter sakazakii ATCC BAA-894 5551552 YP_001436721.1 CDS ESA_00601 NC_009778.1 568387 568569 R COG: NOG35541 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(568387..568569) Cronobacter sakazakii ATCC BAA-894 5551425 YP_001436722.1 CDS ESA_00602 NC_009778.1 568654 568950 D KEGG: pae:PA1977 0.0015 sensor protein GLPS; COG: COG0401 Uncharacterized homolog of Blt101; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 568654..568950 Cronobacter sakazakii ATCC BAA-894 5552106 YP_001436723.1 CDS ESA_00603 NC_009778.1 569329 571161 D KEGG: san:gbs1713 0.0044 similar to Glu-tRNA Gln amidotransferase subunit C K02435; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 569329..571161 Cronobacter sakazakii ATCC BAA-894 5552478 YP_001436724.1 CDS ESA_00605 NC_009778.1 571286 571690 R Psort location: mitochondrial, score: 23; hypothetical protein complement(571286..571690) Cronobacter sakazakii ATCC BAA-894 5551547 YP_001436725.1 CDS ESA_00604 NC_009778.1 571545 571745 D Psort location: cytoplasmic, score: 23; hypothetical protein 571545..571745 Cronobacter sakazakii ATCC BAA-894 5551553 YP_001436726.1 CDS ESA_00606 NC_009778.1 571993 572448 D COG: NOG27817 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 571993..572448 Cronobacter sakazakii ATCC BAA-894 5549424 YP_001436727.1 CDS ESA_00607 NC_009778.1 572439 572786 D COG: NOG11501 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 572439..572786 Cronobacter sakazakii ATCC BAA-894 5551550 YP_001436728.1 CDS ESA_00608 NC_009778.1 573070 573357 D KEGG: tth:TTC0552 0.0027 esterase; COG: COG0824 Predicted THIoesterase; Psort location: cytoplasmic, score: 23; hypothetical protein 573070..573357 Cronobacter sakazakii ATCC BAA-894 5551508 YP_001436729.1 CDS ESA_00609 NC_009778.1 573625 573762 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(573625..573762) Cronobacter sakazakii ATCC BAA-894 5551548 YP_001436730.1 CDS ESA_00610 NC_009778.1 573812 577054 R KEGG: mbo:Mb2127 7.0e-55 helZ; probable helicase HelZ; COG: COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(573812..577054) Cronobacter sakazakii ATCC BAA-894 5551516 YP_001436731.1 CDS ESA_00611 NC_009778.1 577054 578742 R COG: NOG37979 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(577054..578742) Cronobacter sakazakii ATCC BAA-894 5551506 YP_001436732.1 CDS ESA_00612 NC_009778.1 578739 579479 R COG: NOG37734 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(578739..579479) Cronobacter sakazakii ATCC BAA-894 5551511 YP_001436733.1 CDS ESA_00613 NC_009778.1 579493 581682 R KEGG: rno:64012 2.0e-07 Rad50; RAD50 homolog (S. cerevisiae); COG: NOG19849 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(579493..581682) Cronobacter sakazakii ATCC BAA-894 5551526 YP_001436734.1 CDS ESA_00614 NC_009778.1 582020 583729 D KEGG: mma:MM0429 5.9e-237 type I restriction-modification system methylation subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 582020..583729 Cronobacter sakazakii ATCC BAA-894 5551453 YP_001436735.1 CDS ESA_00615 NC_009778.1 583719 585170 D KEGG: rba:RB11377 2.0e-54 hsdS; probable HsdS polypeptide, part of CfrA family K01154; COG: COG0732 Restriction endonuclease S subunits; Psort location: cytoplasmic, score: 23; hypothetical protein 583719..585170 Cronobacter sakazakii ATCC BAA-894 5551513 YP_001436736.1 CDS ESA_00616 NC_009778.1 585163 586350 D COG: NOG18152 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 585163..586350 Cronobacter sakazakii ATCC BAA-894 5551498 YP_001436737.1 CDS ESA_00617 NC_009778.1 586350 589481 D KEGG: mma:MM0431 0. type I restriction-modification system restriction subnit K01153; COG: COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Psort location: cytoplasmic, score: 23; hypothetical protein 586350..589481 Cronobacter sakazakii ATCC BAA-894 5551503 YP_001436738.1 CDS ESA_00618 NC_009778.1 590288 591835 D KEGG: hpa:HPAG1_0593 0.00080 ABC transporter, ATP-binding protein; COG: NOG08709 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 590288..591835 Cronobacter sakazakii ATCC BAA-894 5551463 YP_001436739.1 CDS ESA_00619 NC_009778.1 592073 592207 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(592073..592207) Cronobacter sakazakii ATCC BAA-894 5551495 YP_001436740.1 CDS ESA_00620 NC_009778.1 592839 595154 R KEGG: sty:STY4832 1.4e-237 Bacteriophage P4 DNA primase; COG: COG4643 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(592839..595154) Cronobacter sakazakii ATCC BAA-894 5551510 YP_001436741.1 CDS ESA_00622 NC_009778.1 595168 595509 R COG: NOG29857 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(595168..595509) Cronobacter sakazakii ATCC BAA-894 5551423 YP_001436742.1 CDS ESA_00623 NC_009778.1 595496 595762 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(595496..595762) Cronobacter sakazakii ATCC BAA-894 5551431 YP_001436743.1 CDS ESA_00621 NC_009778.1 595508 595753 D Psort location: cytoplasmic, score: 23; hypothetical protein 595508..595753 Cronobacter sakazakii ATCC BAA-894 5551434 YP_001436744.1 CDS ESA_00624 NC_009778.1 595759 596091 R COG: NOG20798 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(595759..596091) Cronobacter sakazakii ATCC BAA-894 5551504 YP_001436745.1 CDS ESA_00625 NC_009778.1 596545 596727 R COG: COG3311 Predicted transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(596545..596727) Cronobacter sakazakii ATCC BAA-894 5551458 YP_001436746.1 CDS ESA_00626 NC_009778.1 597311 598021 D COG: NOG23022 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 597311..598021 Cronobacter sakazakii ATCC BAA-894 5551432 YP_001436747.1 CDS ESA_00627 NC_009778.1 598018 598269 D COG: NOG23021 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 598018..598269 Cronobacter sakazakii ATCC BAA-894 5551424 YP_001436748.1 CDS ESA_00628 NC_009778.1 598550 599245 R COG: NOG36458 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(598550..599245) Cronobacter sakazakii ATCC BAA-894 5551477 YP_001436749.1 CDS ESA_00629 NC_009778.1 599242 600612 R COG: COG3950 Predicted ATP-binding protein involved in virulence; Psort location: nuclear, score: 23; hypothetical protein complement(599242..600612) Cronobacter sakazakii ATCC BAA-894 5551439 YP_001436750.1 CDS ESA_00630 NC_009778.1 600617 601816 R COG: COG0582 Integrase; Psort location: nuclear, score: 23; hypothetical protein complement(600617..601816) Cronobacter sakazakii ATCC BAA-894 5551469 YP_001436751.1 CDS ESA_00632 NC_009778.1 602675 602908 R Psort location: nuclear, score: 23; hypothetical protein complement(602675..602908) Cronobacter sakazakii ATCC BAA-894 5551381 YP_001436752.1 CDS ESA_00633 NC_009778.1 602971 603543 D COG: COG5295 Autotransporter adhesin; Psort location: cytoplasmic, score: 23; hypothetical protein 602971..603543 Cronobacter sakazakii ATCC BAA-894 5551428 YP_001436753.1 CDS ESA_00634 NC_009778.1 603515 603739 D COG: COG0845 Membrane-fusion protein; Psort location: cytoplasmic, score: 23; hypothetical protein 603515..603739 Cronobacter sakazakii ATCC BAA-894 5551429 YP_001436754.1 CDS ESA_00635 NC_009778.1 603961 604443 R COG: COG0691 tmRNA-binding protein; Psort location: mitochondrial, score: 23; hypothetical protein complement(603961..604443) Cronobacter sakazakii ATCC BAA-894 5551383 YP_001436755.1 CDS ESA_00636 NC_009778.1 604592 605029 D KEGG: tfu:Tfu_1222 1.5e-05 actinorhodin polyketide synthase bifunctional cyclase/dehydratase K05554; COG: COG2867 Oligoketide cyclase/lipid transport protein; Psort location: cytoplasmic, score: 23; hypothetical protein 604592..605029 Cronobacter sakazakii ATCC BAA-894 5551448 YP_001436756.1 CDS ESA_00637 NC_009778.1 605019 605309 D COG: COG2914 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 605019..605309 Cronobacter sakazakii ATCC BAA-894 5551447 YP_001436757.1 CDS ESA_00638 NC_009778.1 605419 605763 R COG: COG2913 Small protein A (tmRNA-binding); Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(605419..605763) Cronobacter sakazakii ATCC BAA-894 5551375 YP_001436758.1 CDS ESA_00640 NC_009778.1 605981 607078 R COG: COG0497 ATPase involved in DNA repair; Psort location: cytoplasmic, score: 23; hypothetical protein complement(605981..607078) Cronobacter sakazakii ATCC BAA-894 5551418 YP_001436759.1 CDS ESA_00639 NC_009778.1 607070 607630 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 607070..607630 Cronobacter sakazakii ATCC BAA-894 5551415 YP_001436760.1 CDS ppnK NC_009778.1 607729 608607 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(607729..608607) Cronobacter sakazakii ATCC BAA-894 5551419 YP_001436761.1 CDS ESA_00642 NC_009778.1 608730 609323 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 608730..609323 Cronobacter sakazakii ATCC BAA-894 5551427 YP_001436762.1 CDS ESA_00643 NC_009778.1 609393 610637 R KEGG: ece:Z3906m 2.0e-188 yfjD; uncharacterized CBS domain-containing protein K00638; COG: COG4536 Putative Mg2+ and Co2+ transporter CorB; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(609393..610637) Cronobacter sakazakii ATCC BAA-894 5551405 YP_001436763.1 CDS ESA_00644 NC_009778.1 610701 611495 R KEGG: sat:SYN_00150 3.9e-06 heme export protein apocytochrome heme-lyase; COG: COG4137 ABC-type uncharacterized transport system, permease component; Psort location: plasma membrane, score: 23; hypothetical protein complement(610701..611495) Cronobacter sakazakii ATCC BAA-894 5551394 YP_001436764.1 CDS ESA_00645 NC_009778.1 611658 613019 D with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 611658..613019 Cronobacter sakazakii ATCC BAA-894 5551430 YP_001436765.1 CDS rpsP NC_009778.1 613242 613526 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 613242..613526 Cronobacter sakazakii ATCC BAA-894 5551421 YP_001436766.1 CDS rimM NC_009778.1 613542 614093 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 613542..614093 Cronobacter sakazakii ATCC BAA-894 5551384 YP_001436767.1 CDS trmD NC_009778.1 614124 614897 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 614124..614897 Cronobacter sakazakii ATCC BAA-894 5551391 YP_001436768.1 CDS rplS NC_009778.1 614943 615290 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 614943..615290 Cronobacter sakazakii ATCC BAA-894 5551389 YP_001436769.1 CDS ESA_00650 NC_009778.1 615298 615426 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(615298..615426) Cronobacter sakazakii ATCC BAA-894 5551396 YP_001436770.1 CDS ESA_00651 NC_009778.1 615505 615897 D COG: NOG22124 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 615505..615897 Cronobacter sakazakii ATCC BAA-894 5551372 YP_001436771.1 CDS ESA_00652 NC_009778.1 615951 617318 D KEGG: btk:BT9727_4489 3.4e-20 cysJ; sulfite reductase [NADPH], flavoprotein, alpha subunit K00379; COG: COG3182 Uncharacterized iron-regulated membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 615951..617318 Cronobacter sakazakii ATCC BAA-894 5551377 YP_001436772.1 CDS ESA_00653 NC_009778.1 617517 618587 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 617517..618587 Cronobacter sakazakii ATCC BAA-894 5551395 YP_001436773.1 CDS tyrA NC_009778.1 618599 619720 D catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 618599..619720 Cronobacter sakazakii ATCC BAA-894 5551388 YP_001436774.1 CDS ESA_00655 NC_009778.1 619788 620666 D KEGG: pub:SAR11_0777 7.3e-26 gnl; gluconolactonase K01053; COG: COG3386 Gluconolactonase; Psort location: cytoskeletal, score: 9; hypothetical protein 619788..620666 Cronobacter sakazakii ATCC BAA-894 5551376 YP_001436775.1 CDS pheA NC_009778.1 620697 621857 R catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase complement(620697..621857) Cronobacter sakazakii ATCC BAA-894 5551370 YP_001436776.1 CDS ESA_00657 NC_009778.1 622107 622490 R associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA complement(622107..622490) Cronobacter sakazakii ATCC BAA-894 5551373 YP_001436777.1 CDS ESA_00658 NC_009778.1 622795 624000 D COG: NOG23126 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 622795..624000 Cronobacter sakazakii ATCC BAA-894 5551345 YP_001436778.1 CDS ESA_00659 NC_009778.1 624053 624790 R with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO complement(624053..624790) Cronobacter sakazakii ATCC BAA-894 5551353 YP_001436779.1 CDS rluD NC_009778.1 624920 625900 D responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 624920..625900 Cronobacter sakazakii ATCC BAA-894 5551331 YP_001436780.1 CDS ESA_00661 NC_009778.1 625897 626625 D COG: COG1496 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 625897..626625 Cronobacter sakazakii ATCC BAA-894 5551309 YP_001436781.1 CDS ESA_00662 NC_009778.1 626743 629328 D KEGG: eci:UTI89_C2925 0. clpB; heat shock protein K03695; COG: COG0542 ATPases with chaperone activity, ATP-binding subunit; Psort location: cytoplasmic, score: 23; protein disaggregation chaperone 626743..629328 Cronobacter sakazakii ATCC BAA-894 5551337 YP_001436784.1 CDS ESA_00669 NC_009778.1 634969 635220 R COG: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(634969..635220) Cronobacter sakazakii ATCC BAA-894 5551267 YP_001436785.1 CDS ESA_00670 NC_009778.1 635324 635905 D COG: NOG13395 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 635324..635905 Cronobacter sakazakii ATCC BAA-894 5549738 YP_001436786.1 CDS ESA_00671 NC_009778.1 635947 637755 R KEGG: bpm:BURPS1710b_0946 1.2e-204 poxB; pyruvate decarboxylase K00156; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: cytoplasmic, score: 23; hypothetical protein complement(635947..637755) Cronobacter sakazakii ATCC BAA-894 5551298 YP_001436787.1 CDS ESA_00672 NC_009778.1 637899 638354 D COG: NOG09993 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 637899..638354 Cronobacter sakazakii ATCC BAA-894 5551276 YP_001436788.1 CDS ESA_00673 NC_009778.1 638472 639773 D KEGG: cal:orf19.2425 0.0010 highly conserved hypothetical protein K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; alpha-ketoglutarate transporter 638472..639773 Cronobacter sakazakii ATCC BAA-894 5551262 YP_001436789.1 CDS ESA_00674 NC_009778.1 639770 640120 R COG: COG5544 Predicted periplasmic lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(639770..640120) Cronobacter sakazakii ATCC BAA-894 5551268 YP_001436790.1 CDS pssA NC_009778.1 640147 641502 R catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase complement(640147..641502) Cronobacter sakazakii ATCC BAA-894 5552353 YP_001436791.1 CDS ESA_00676 NC_009778.1 641615 644278 R KEGG: eci:UTI89_C2907 0. yfiQ; hypothetical protein YfiQ K09181; COG: COG1042 Acyl-CoA synthetase (NDP forming); Psort location: cytoplasmic, score: 23; hypothetical protein complement(641615..644278) Cronobacter sakazakii ATCC BAA-894 5551258 YP_001436792.1 CDS ESA_00677 NC_009778.1 644309 644836 R COG: COG3148 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(644309..644836) Cronobacter sakazakii ATCC BAA-894 5551227 YP_001436793.1 CDS ESA_00678 NC_009778.1 645080 645511 R KEGG: sbo:SBO_2614 2.2e-63 trxC; putative THIoredoxin-like protein K03672; COG: COG0526 Thiol-disulfide isomerase and THIoredoxins; Psort location: cytoplasmic, score: 23; thioredoxin 2 complement(645080..645511) Cronobacter sakazakii ATCC BAA-894 5551294 YP_001436794.1 CDS ESA_00679 NC_009778.1 645709 646782 D KEGG: eci:UTI89_C2903 3.1e-144 yfiF; hypothetical tRNA/rRNA methyltransferase YfiF K03214; COG: COG0566 rRNA methylases; Psort location: cytoplasmic, score: 23; putative methyltransferase 645709..646782 Cronobacter sakazakii ATCC BAA-894 5551261 YP_001436795.1 CDS ESA_00680 NC_009778.1 646840 647601 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(646840..647601) Cronobacter sakazakii ATCC BAA-894 5551260 YP_001436796.1 CDS ESA_00681 NC_009778.1 647836 648219 D stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 647836..648219 Cronobacter sakazakii ATCC BAA-894 5549233 YP_001436797.1 CDS ESA_00682 NC_009778.1 648295 649629 R facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB complement(648295..649629) Cronobacter sakazakii ATCC BAA-894 5551236 YP_001436798.1 CDS ESA_00683 NC_009778.1 649725 650495 D KEGG: eci:UTI89_C2897 1.0e-97 yfiC; hypothetical protein YfiC K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: mitochondrial, score: 23; hypothetical protein 649725..650495 Cronobacter sakazakii ATCC BAA-894 5551228 YP_001436799.1 CDS ESA_00684 NC_009778.1 650480 652099 R catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase complement(650480..652099) Cronobacter sakazakii ATCC BAA-894 5551204 YP_001436800.1 CDS ESA_00685 NC_009778.1 652261 652404 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(652261..652404) Cronobacter sakazakii ATCC BAA-894 5551216 YP_001436801.1 CDS ESA_00686 NC_009778.1 652524 653099 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 652524..653099 Cronobacter sakazakii ATCC BAA-894 5551235 YP_001436802.1 CDS ESA_00687 NC_009778.1 653131 653781 D COG: COG3073 Negative regulator of sigma E activity; Psort location: nuclear, score: 23; anti-RNA polymerase sigma factor SigE 653131..653781 Cronobacter sakazakii ATCC BAA-894 5551208 YP_001436803.1 CDS rseB NC_009778.1 653781 654734 D periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 653781..654734 Cronobacter sakazakii ATCC BAA-894 5551193 YP_001436804.1 CDS ESA_00689 NC_009778.1 654731 655210 D involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 654731..655210 Cronobacter sakazakii ATCC BAA-894 5551206 YP_001436805.1 CDS ESA_00690 NC_009778.1 655410 657209 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 655410..657209 Cronobacter sakazakii ATCC BAA-894 5551205 YP_001436806.1 CDS ESA_00691 NC_009778.1 657224 658189 D catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 657224..658189 Cronobacter sakazakii ATCC BAA-894 5551170 YP_001436807.1 CDS era NC_009778.1 659038 659943 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 659038..659943 Cronobacter sakazakii ATCC BAA-894 5551192 YP_001436808.1 CDS ESA_00694 NC_009778.1 659953 660690 D COG: COG1381 Recombinational DNA repair protein (RecF pathway); Psort location: cytoplasmic, score: 23; hypothetical protein 659953..660690 Cronobacter sakazakii ATCC BAA-894 5551173 YP_001436809.1 CDS ESA_00695 NC_009778.1 660765 661496 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 660765..661496 Cronobacter sakazakii ATCC BAA-894 5551187 YP_001436810.1 CDS acpS NC_009778.1 661496 661876 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 661496..661876 Cronobacter sakazakii ATCC BAA-894 5551169 YP_001436811.1 CDS ESA_00697 NC_009778.1 661873 662133 R KEGG: nar:Saro_2292 2.9e-06 NADH-quinone oxidoreductase, chain I K00338; COG: COG1145 Ferredoxin; Psort location: nuclear, score: 23; hypothetical protein complement(661873..662133) Cronobacter sakazakii ATCC BAA-894 5551152 YP_001436812.1 CDS ESA_00698 NC_009778.1 662190 663038 R KEGG: bte:BTH_I1550 1.5e-21 glucokinase/transcriptional regulator, RpiR family, fusion K00845; COG: COG1737 Transcriptional regulators; Psort location: cytoplasmic, score: 23; putative DNA-binding transcriptional regulator complement(662190..663038) Cronobacter sakazakii ATCC BAA-894 5551177 YP_001436813.1 CDS murQ NC_009778.1 663160 664053 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 663160..664053 Cronobacter sakazakii ATCC BAA-894 5548545 YP_001436814.1 CDS ESA_00700 NC_009778.1 664067 665434 D KEGG: sec:SC2565 1.7e-200 yfeV; putative phosphotransferase system IIB components K02809:K02810; COG: COG1264 Phosphotransferase system IIB components; Psort location: plasma membrane, score: 23; hypothetical protein 664067..665434 Cronobacter sakazakii ATCC BAA-894 5548536 YP_001436815.1 CDS ESA_00701 NC_009778.1 665438 666073 D COG: COG0560 Phosphoserine phosphatase; Psort location: cytoplasmic, score: 23; hypothetical protein 665438..666073 Cronobacter sakazakii ATCC BAA-894 5548851 YP_001436816.1 CDS ESA_00702 NC_009778.1 666019 666660 D KEGG: stt:t0289 5.8e-72 yfhC; hypothetical protein K01500; COG: COG0590 Cytosine/adenosine deaminases; Psort location: mitochondrial, score: 23; hypothetical protein 666019..666660 Cronobacter sakazakii ATCC BAA-894 5548858 YP_001436817.1 CDS ESA_00703 NC_009778.1 666533 668092 R YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase complement(666533..668092) Cronobacter sakazakii ATCC BAA-894 5548883 YP_001436818.1 CDS ESA_00704 NC_009778.1 668360 672250 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 668360..672250 Cronobacter sakazakii ATCC BAA-894 5548861 YP_001436819.1 CDS ESA_00706 NC_009778.1 672871 674262 D KEGG: sec:SC2559 7.1e-186 yfhK; putative sensory kinase in regulatory system K07711; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 672871..674262 Cronobacter sakazakii ATCC BAA-894 5549078 YP_001436820.1 CDS ESA_00707 NC_009778.1 674373 675032 D COG: NOG06210 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 674373..675032 Cronobacter sakazakii ATCC BAA-894 5549544 YP_001436821.1 CDS ESA_00708 NC_009778.1 675029 676366 D KEGG: eci:UTI89_C2502 4.2e-85 atoC; acetoacetate metabolism regulatory protein AtoC K07714; COG: COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; Psort location: cytoplasmic, score: 23; hypothetical protein 675029..676366 Cronobacter sakazakii ATCC BAA-894 5550824 YP_001436822.1 CDS ESA_00709 NC_009778.1 676465 676803 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 676465..676803 Cronobacter sakazakii ATCC BAA-894 5549011 YP_001436823.1 CDS ESA_00710 NC_009778.1 677084 678274 R flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase complement(677084..678274) Cronobacter sakazakii ATCC BAA-894 5548180 YP_001436824.1 CDS glyA NC_009778.1 678591 679850 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 678591..679850 Cronobacter sakazakii ATCC BAA-894 5548720 YP_001436825.1 CDS ESA_00712 NC_009778.1 679922 680284 D KEGG: vfi:VFA0114 1.1e-06 methyltransferase K00599; COG: COG0789 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 679922..680284 Cronobacter sakazakii ATCC BAA-894 5548758 YP_001436826.1 CDS ESA_00713 NC_009778.1 680340 680717 D KEGG: she:Shewmr4_0089 1.3e-42 carboxymuconolactone decarboxylase K01607; COG: COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 680340..680717 Cronobacter sakazakii ATCC BAA-894 5548749 YP_001436827.1 CDS ESA_00714 NC_009778.1 680778 681980 D putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 680778..681980 Cronobacter sakazakii ATCC BAA-894 5548700 YP_001436828.1 CDS ESA_00715 NC_009778.1 681977 683188 R KEGG: spb:M28_Spy1064 7.6e-05 PTS system, mannitol (cryptic)-specific IIA component K00890; COG: COG3711 Transcriptional antiterminator; Psort location: cytoplasmic, score: 23; stationary phase inducible protein CsiE complement(681977..683188) Cronobacter sakazakii ATCC BAA-894 5548731 YP_001436829.1 CDS ESA_00716 NC_009778.1 683311 684030 D COG: COG3683 ABC-type uncharacterized transport system, periplasmic component; Psort location: mitochondrial, score: 23; hypothetical protein 683311..684030 Cronobacter sakazakii ATCC BAA-894 5552161 YP_001436830.1 CDS ESA_00717 NC_009778.1 684021 684998 D COG: COG2215 ABC-type uncharacterized transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 684021..684998 Cronobacter sakazakii ATCC BAA-894 5552052 YP_001436831.1 CDS ESA_00718 NC_009778.1 685215 686009 R KEGG: spt:SPA0320 4.1e-126 suhB; extragenic suppressor protein SuhB K01092; COG: COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; Psort location: cytoplasmic, score: 23; inositol monophosphatase complement(685215..686009) Cronobacter sakazakii ATCC BAA-894 5549650 YP_001436832.1 CDS ESA_00719 NC_009778.1 686140 686877 D KEGG: stm:STM2545 3.5e-113 putative rRNA methylase K02533; COG: COG0565 rRNA methylase; Psort location: cytoplasmic, score: 23; hypothetical protein 686140..686877 Cronobacter sakazakii ATCC BAA-894 5549643 YP_001436833.1 CDS ESA_00720 NC_009778.1 687009 687497 D regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 687009..687497 Cronobacter sakazakii ATCC BAA-894 5549579 YP_001436834.1 CDS ESA_00722 NC_009778.1 687384 687614 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(687384..687614) Cronobacter sakazakii ATCC BAA-894 5549618 YP_001436835.1 CDS ESA_00721 NC_009778.1 687614 688828 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 687614..688828 Cronobacter sakazakii ATCC BAA-894 5549592 YP_001436836.1 CDS ESA_00723 NC_009778.1 688857 689243 D KEGG: rxy:Rxyl_1354 7.6e-16 tRNA (5-methylaminomethyl-2-THIouridylate)-methyltransferase K00566; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: cytoplasmic, score: 23; scaffold protein 688857..689243 Cronobacter sakazakii ATCC BAA-894 5549572 YP_001436837.1 CDS iscA NC_009778.1 689268 689591 D forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 689268..689591 Cronobacter sakazakii ATCC BAA-894 5549559 YP_001436838.1 CDS ESA_00725 NC_009778.1 690066 690188 D COG: COG1076 DnaJ-domain-containing proteins 1; Psort location: cytoplasmic, score: 23; hypothetical protein 690066..690188 Cronobacter sakazakii ATCC BAA-894 5549541 YP_001436839.1 CDS hscA NC_009778.1 690204 692054 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 690204..692054 Cronobacter sakazakii ATCC BAA-894 5550881 YP_001436840.1 CDS ESA_00727 NC_009778.1 692057 692392 D KEGG: eci:UTI89_C2847 7.5e-56 fdx; ferredoxin, 2Fe-2S K04755; COG: COG0633 Ferredoxin; Psort location: cytoplasmic, score: 23; hypothetical protein 692057..692392 Cronobacter sakazakii ATCC BAA-894 5550891 YP_001436841.1 CDS ESA_00728 NC_009778.1 692394 692594 D COG: COG2975 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 692394..692594 Cronobacter sakazakii ATCC BAA-894 5551098 YP_001436842.1 CDS ESA_00729 NC_009778.1 692658 693944 D catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 692658..693944 Cronobacter sakazakii ATCC BAA-894 5549492 YP_001436843.1 CDS ESA_00730 NC_009778.1 694263 695060 D enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 694263..695060 Cronobacter sakazakii ATCC BAA-894 5549491 YP_001436844.1 CDS ESA_00731 NC_009778.1 695270 697378 D KEGG: aci:ACIAD2833 7.6e-05 htpX; heat shock protein K03799; COG: COG0501 Zn-dependent protease with chaperone function; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 695270..697378 Cronobacter sakazakii ATCC BAA-894 5550855 YP_001436845.1 CDS ESA_00732 NC_009778.1 697491 699617 D KEGG: aci:ACIAD2833 4.8e-10 htpX; heat shock protein K03799; COG: COG0501 Zn-dependent protease with chaperone function; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 697491..699617 Cronobacter sakazakii ATCC BAA-894 5549020 YP_001436846.1 CDS ESA_00733 NC_009778.1 699646 700419 R KEGG: bte:BTH_I1550 4.8e-09 glucokinase/transcriptional regulator, RpiR family, fusion K00845; COG: COG1737 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(699646..700419) Cronobacter sakazakii ATCC BAA-894 5552399 YP_001436847.1 CDS sseA NC_009778.1 700419 701267 R catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase complement(700419..701267) Cronobacter sakazakii ATCC BAA-894 5550777 YP_001436848.1 CDS ESA_00735 NC_009778.1 701360 702727 R KEGG: eca:ECA3226 4.0e-215 6-phospho-alpha-glucosidase K01232; COG: COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(701360..702727) Cronobacter sakazakii ATCC BAA-894 5550841 YP_001436849.1 CDS ESA_00736 NC_009778.1 702737 704281 R KEGG: eca:ECA3225 8.9e-211 PTS system, alpha-glucoside-specific IIbc component K02790:K02791; COG: COG1264 Phosphotransferase system IIB components; Psort location: plasma membrane, score: 23; hypothetical protein complement(702737..704281) Cronobacter sakazakii ATCC BAA-894 5550664 YP_001436850.1 CDS ESA_00737 NC_009778.1 704605 709554 D COG: COG2373 Large extracellular alpha-helical protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 704605..709554 Cronobacter sakazakii ATCC BAA-894 5550821 YP_001436851.1 CDS ESA_00738 NC_009778.1 709565 711898 D penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 709565..711898 Cronobacter sakazakii ATCC BAA-894 5550781 YP_001436852.1 CDS ESA_00740 NC_009778.1 712021 712512 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(712021..712512) Cronobacter sakazakii ATCC BAA-894 5550818 YP_001436853.1 CDS ndk NC_009778.1 712066 712497 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 712066..712497 Cronobacter sakazakii ATCC BAA-894 5550819 YP_001436854.1 CDS ESA_00741 NC_009778.1 712678 713844 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 712678..713844 Cronobacter sakazakii ATCC BAA-894 5550794 YP_001436855.1 CDS ESA_00743 NC_009778.1 713868 713993 R Psort location: mitochondrial, score: 23; hypothetical protein complement(713868..713993) Cronobacter sakazakii ATCC BAA-894 5550814 YP_001436856.1 CDS ESA_00742 NC_009778.1 713970 714110 D Psort location: mitochondrial, score: 23; hypothetical protein 713970..714110 Cronobacter sakazakii ATCC BAA-894 5550791 YP_001436857.1 CDS ESA_00744 NC_009778.1 714263 715279 D KEGG: ava:Ava_3308 0.00022 serine/threonine protein kinase K08884; COG: COG1426 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; cytoskeletal protein RodZ 714263..715279 Cronobacter sakazakii ATCC BAA-894 5550796 YP_001436858.1 CDS ispG NC_009778.1 715306 716424 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 715306..716424 Cronobacter sakazakii ATCC BAA-894 5550778 YP_001436859.1 CDS hisS NC_009778.1 716569 717813 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 716569..717813 Cronobacter sakazakii ATCC BAA-894 5550770 YP_001436860.1 CDS ESA_00747 NC_009778.1 717849 718469 D COG: COG2976 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 717849..718469 Cronobacter sakazakii ATCC BAA-894 5550753 YP_001436861.1 CDS ESA_00748 NC_009778.1 718480 719661 D with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 718480..719661 Cronobacter sakazakii ATCC BAA-894 5550766 YP_001436862.1 CDS engA NC_009778.1 719782 721260 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 719782..721260 Cronobacter sakazakii ATCC BAA-894 5550747 YP_001436863.1 CDS ESA_00750 NC_009778.1 721278 721532 D KEGG: aha:AHA_1764 2.9e-15 ubiquitin ligase sinat5 K01932; COG: NOG17950 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 721278..721532 Cronobacter sakazakii ATCC BAA-894 5550756 YP_001436864.1 CDS ESA_00751 NC_009778.1 721529 721879 R COG: NOG18711 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(721529..721879) Cronobacter sakazakii ATCC BAA-894 5550755 YP_001436865.1 CDS ESA_00752 NC_009778.1 721879 722904 R KEGG: eca:ECA3211 1.8e-123 prt1; extracellular metalloprotease; COG: COG3227 Zinc metalloprotease (elastase); Psort location: cytoplasmic, score: 23; hypothetical protein complement(721879..722904) Cronobacter sakazakii ATCC BAA-894 5550736 YP_001436866.1 CDS xseA NC_009778.1 722987 724360 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(722987..724360) Cronobacter sakazakii ATCC BAA-894 5550748 YP_001436867.1 CDS ESA_00754 NC_009778.1 724531 725997 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 724531..725997 Cronobacter sakazakii ATCC BAA-894 5550737 YP_001436868.1 CDS guaA NC_009778.1 726064 727641 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 726064..727641 Cronobacter sakazakii ATCC BAA-894 5550730 YP_001436869.1 CDS ESA_00756 NC_009778.1 727910 728227 D COG: NOG31354 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 727910..728227 Cronobacter sakazakii ATCC BAA-894 5550716 YP_001436870.1 CDS ESA_00757 NC_009778.1 728027 728230 R COG: NOG13900 non supervised orthologous group; Psort location: golgi, score: 9; hypothetical protein complement(728027..728230) Cronobacter sakazakii ATCC BAA-894 5550713 YP_001436871.1 CDS ESA_00758 NC_009778.1 728586 730823 D KEGG: vfi:VF0494 2.9e-25 sensory transduction protein kinase; COG: COG2199 FOG: GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 728586..730823 Cronobacter sakazakii ATCC BAA-894 5550679 YP_001436872.1 CDS ESA_00759 NC_009778.1 730858 732399 R KEGG: sty:STY2743 1.6e-236 ppx; exopolyphosphatase K01514; COG: COG0248 Exopolyphosphatase; Psort location: endoplasmic reticulum, score: 9; exopolyphosphatase complement(730858..732399) Cronobacter sakazakii ATCC BAA-894 5550653 YP_001436873.1 CDS ESA_00760 NC_009778.1 732403 734463 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(732403..734463) Cronobacter sakazakii ATCC BAA-894 5550719 YP_001436874.1 CDS purN NC_009778.1 734701 735342 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(734701..735342) Cronobacter sakazakii ATCC BAA-894 5550672 YP_001436875.1 CDS ESA_00762 NC_009778.1 735342 736379 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(735342..736379) Cronobacter sakazakii ATCC BAA-894 5550650 YP_001436876.1 CDS ESA_00763 NC_009778.1 736513 737238 D KEGG: eci:UTI89_C2814 1.6e-101 upp; uracil phosphoribosyltransferase K00761; COG: COG0035 Uracil phosphoribosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 736513..737238 Cronobacter sakazakii ATCC BAA-894 5552199 YP_001436877.1 CDS ESA_00764 NC_009778.1 737320 738609 D KEGG: bcz:BCZK0244 3.6e-07 guanine-hypoxanTHIne permease; xanTHIne/uracil permease family protein K06901; COG: COG2233 XanTHIne/uracil permeases; Psort location: plasma membrane, score: 23; uracil transporter 737320..738609 Cronobacter sakazakii ATCC BAA-894 5552402 YP_001436878.1 CDS ESA_00765 NC_009778.1 738729 739406 D controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 738729..739406 Cronobacter sakazakii ATCC BAA-894 5550659 YP_001436879.1 CDS ESA_00766 NC_009778.1 739457 739813 R KEGG: pha:PSHAa1133 3.8e-36 arsenate reductase; COG: COG1393 Arsenate reductase and related proteins, glutaredoxin family; Psort location: nuclear, score: 23; hypothetical protein complement(739457..739813) Cronobacter sakazakii ATCC BAA-894 5550660 YP_001436880.1 CDS ESA_00767 NC_009778.1 739825 741291 R KEGG: eci:UTI89_C2810 3.5e-216 yfgC; hypothetical protein YfgC precursor; COG: COG4783 Putative Zn-dependent protease, contains TPR repeats; Psort location: nuclear, score: 23; hypothetical protein complement(739825..741291) Cronobacter sakazakii ATCC BAA-894 5550645 YP_001436881.1 CDS ESA_00768 NC_009778.1 741514 742578 D KEGG: tbd:Tbd_2668 1.2e-28 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: plasma membrane, score: 23; hypothetical protein 741514..742578 Cronobacter sakazakii ATCC BAA-894 5550628 YP_001436882.1 CDS bcp NC_009778.1 742624 743097 R bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase complement(742624..743097) Cronobacter sakazakii ATCC BAA-894 5550640 YP_001436883.1 CDS ESA_00770 NC_009778.1 743097 743540 R KEGG: eci:UTI89_C2806 5.5e-60 gcvR; glycine cleavage system transcriptional repressor K03567; COG: COG2716 Glycine cleavage system regulatory protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(743097..743540) Cronobacter sakazakii ATCC BAA-894 5550613 YP_001436884.1 CDS ESA_00771 NC_009778.1 743814 744692 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 743814..744692 Cronobacter sakazakii ATCC BAA-894 5550609 YP_001436885.1 CDS ESA_00772 NC_009778.1 744709 745743 D COG: COG3317 Uncharacterized lipoprotein; Psort location: nuclear, score: 23; lipoprotein 744709..745743 Cronobacter sakazakii ATCC BAA-894 5550603 YP_001436886.1 CDS ESA_00773 NC_009778.1 745873 746586 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 745873..746586 Cronobacter sakazakii ATCC BAA-894 5550597 YP_001436887.1 CDS ESA_00774 NC_009778.1 746778 747575 D KEGG: eci:UTI89_C2802 1.8e-125 ypfJ; hypothetical protein; COG: COG2321 Predicted metalloprotease; Psort location: mitochondrial, score: 23; hypothetical protein 746778..747575 Cronobacter sakazakii ATCC BAA-894 5550583 YP_001436888.1 CDS ESA_00775 NC_009778.1 747591 749618 D KEGG: mes:Meso_0392 0.0014 GCN5-related N-acetyltransferase K03824; COG: COG1444 Predicted P-loop ATPase fused to an acetyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 747591..749618 Cronobacter sakazakii ATCC BAA-894 5550608 YP_001436889.1 CDS ESA_00776 NC_009778.1 749677 750390 D Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 749677..750390 Cronobacter sakazakii ATCC BAA-894 5550599 YP_001436890.1 CDS ESA_00777 NC_009778.1 750451 750639 R COG: NOG13899 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(750451..750639) Cronobacter sakazakii ATCC BAA-894 5550590 YP_001436891.1 CDS ESA_00778 NC_009778.1 750668 751795 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(750668..751795) Cronobacter sakazakii ATCC BAA-894 5550571 YP_001436892.1 CDS ESA_00779 NC_009778.1 751800 752156 R KEGG: eci:UTI89_C2797 2.0e-48 yffB; conserved THIoredoxin-like protein; COG: COG1393 Arsenate reductase and related proteins, glutaredoxin family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(751800..752156) Cronobacter sakazakii ATCC BAA-894 5550570 YP_001436893.1 CDS ESA_00780 NC_009778.1 752261 752692 R KEGG: fnu:FN1006 2.6e-07 acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(752261..752692) Cronobacter sakazakii ATCC BAA-894 5550576 YP_001436894.1 CDS ESA_00781 NC_009778.1 753055 756171 R KEGG: eci:UTI89_C2351 8.4e-112 yegO; hypothetical protein YegO K07789; COG: COG0841 Cation/multidrug efflux pump; Psort location: plasma membrane, score: 23; aminoglycoside/multidrug efflux system complement(753055..756171) Cronobacter sakazakii ATCC BAA-894 5550594 YP_001436895.1 CDS ESA_00782 NC_009778.1 756306 756950 R nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP complement(756306..756950) Cronobacter sakazakii ATCC BAA-894 5550567 YP_001436896.1 CDS ESA_00783 NC_009778.1 757148 757723 D KEGG: eci:UTI89_C2793 3.4e-76 yffH; hypothetical protein YffH K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 757148..757723 Cronobacter sakazakii ATCC BAA-894 5550551 YP_001436897.1 CDS ESA_00784 NC_009778.1 757853 758896 D COG: NOG06758 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 757853..758896 Cronobacter sakazakii ATCC BAA-894 5550564 YP_001436898.1 CDS ESA_00785 NC_009778.1 758972 759916 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 758972..759916 Cronobacter sakazakii ATCC BAA-894 5550579 YP_001436899.1 CDS ESA_00786 NC_009778.1 759953 760120 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(759953..760120) Cronobacter sakazakii ATCC BAA-894 5550555 YP_001436900.1 CDS ESA_00787 NC_009778.1 760611 761003 D COG: NOG26784 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 760611..761003 Cronobacter sakazakii ATCC BAA-894 5550566 YP_001436901.1 CDS ESA_00788 NC_009778.1 761197 763203 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(761197..763203) Cronobacter sakazakii ATCC BAA-894 5550537 YP_001436902.1 CDS ESA_00789 NC_009778.1 763212 764162 R KEGG: sty:STY2710 2.5e-142 talA; transaldolase A K00616; COG: COG0176 Transaldolase; Psort location: cytoplasmic, score: 23; transaldolase A complement(763212..764162) Cronobacter sakazakii ATCC BAA-894 5550527 YP_001436903.1 CDS ESA_00790 NC_009778.1 764444 766723 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 764444..766723 Cronobacter sakazakii ATCC BAA-894 5550518 YP_001436904.1 CDS ESA_00791 NC_009778.1 766849 767640 R KEGG: ecj:JW0580 1.1e-111 fepC; iron-enterobactin transporter subunit K02013; COG: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(766849..767640) Cronobacter sakazakii ATCC BAA-894 5550529 YP_001436905.1 CDS ESA_00792 NC_009778.1 767637 768629 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(767637..768629) Cronobacter sakazakii ATCC BAA-894 5550520 YP_001436906.1 CDS ESA_00793 NC_009778.1 768626 769606 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(768626..769606) Cronobacter sakazakii ATCC BAA-894 5550510 YP_001436907.1 CDS ESA_00794 NC_009778.1 769741 770985 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 769741..770985 Cronobacter sakazakii ATCC BAA-894 5550497 YP_001436908.1 CDS ESA_00795 NC_009778.1 771011 771970 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(771011..771970) Cronobacter sakazakii ATCC BAA-894 5550484 YP_001436909.1 CDS ESA_00796 NC_009778.1 772157 773323 D KEGG: eco:b0593 1.4e-134 entC, fepF; isochorismate hydroxymutase 2, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase; Psort location: cytoplasmic, score: 23; hypothetical protein 772157..773323 Cronobacter sakazakii ATCC BAA-894 5550470 YP_001436910.1 CDS entE NC_009778.1 773334 774938 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 773334..774938 Cronobacter sakazakii ATCC BAA-894 5550486 YP_001436911.1 CDS ESA_00798 NC_009778.1 774948 775817 D KEGG: ece:Z0737 5.3e-126 entB; 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: cytoplasmic, score: 23; hypothetical protein 774948..775817 Cronobacter sakazakii ATCC BAA-894 5550408 YP_001436912.1 CDS ESA_00799 NC_009778.1 775814 776566 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 775814..776566 Cronobacter sakazakii ATCC BAA-894 5550461 YP_001436913.1 CDS ESA_00800 NC_009778.1 776567 776980 D KEGG: eco:b0597 7.8e-61 ybdB; hypothetical protein; COG: COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; Psort location: cytoplasmic, score: 23; hypothetical protein 776567..776980 Cronobacter sakazakii ATCC BAA-894 5550485 YP_001436914.1 CDS ESA_00801 NC_009778.1 777493 779598 D KEGG: xtr:3283503 0.00072 ND6; NADH dehydrogenase subunit 6 K03884; COG: COG1966 Carbon starvation protein, predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein 777493..779598 Cronobacter sakazakii ATCC BAA-894 5550473 YP_001436915.1 CDS ESA_00802 NC_009778.1 779754 780050 D COG: COG2879 Uncharacterized small protein; Psort location: cytoplasmic, score: 23; hypothetical protein 779754..780050 Cronobacter sakazakii ATCC BAA-894 5550452 YP_001436916.1 CDS ESA_00803 NC_009778.1 780061 780441 R COG: COG1396 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(780061..780441) Cronobacter sakazakii ATCC BAA-894 5550447 YP_001436917.1 CDS ESA_00804 NC_009778.1 780456 780719 R COG: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; Psort location: cytoplasmic, score: 23; hypothetical protein complement(780456..780719) Cronobacter sakazakii ATCC BAA-894 5550398 YP_001436918.1 CDS ESA_00805 NC_009778.1 780901 782136 R KEGG: gme:Gmet_0086 2.5e-12 2-acyl-glycerophospho-ethanolamine acyltransferase K05939:K01909; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(780901..782136) Cronobacter sakazakii ATCC BAA-894 5550432 YP_001436919.1 CDS ESA_00806 NC_009778.1 782251 783366 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(782251..783366) Cronobacter sakazakii ATCC BAA-894 5550448 YP_001436920.1 CDS ESA_00807 NC_009778.1 783600 785105 D KEGG: eca:ECA2719 1.9e-185 ABC transporter, ATP-binding protein K02056; COG: COG1129 ABC-type sugar transport system, ATPase component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 783600..785105 Cronobacter sakazakii ATCC BAA-894 5550418 YP_001436921.1 CDS ESA_00808 NC_009778.1 785102 786097 D KEGG: msm:MSMEG_4171 4.8e-45 ribose transport system permease protein RbsC; COG: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; Psort location: plasma membrane, score: 23; hypothetical protein 785102..786097 Cronobacter sakazakii ATCC BAA-894 5550427 YP_001436922.1 CDS ESA_00809 NC_009778.1 786121 787185 D KEGG: bpm:BURPS1710b_A0023 2.4e-11 ABC transporter, ATP-binding protein domain protein K02056; COG: COG1879 ABC-type sugar transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 786121..787185 Cronobacter sakazakii ATCC BAA-894 5550426 YP_001436923.1 CDS ESA_00810 NC_009778.1 787185 788429 D COG: COG5276 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 787185..788429 Cronobacter sakazakii ATCC BAA-894 5551938 YP_001436924.1 CDS mtnK NC_009778.1 788547 789761 R phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway; methylthioribose kinase complement(788547..789761) Cronobacter sakazakii ATCC BAA-894 5550443 YP_001436925.1 CDS ESA_00812 NC_009778.1 789852 790871 D KEGG: eca:ECA3477 6.7e-142 methylTHIoribose-1-phosphate isomerase K08963; COG: COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 789852..790871 Cronobacter sakazakii ATCC BAA-894 5550391 YP_001436926.1 CDS ESA_00813 NC_009778.1 790902 791807 R catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase complement(790902..791807) Cronobacter sakazakii ATCC BAA-894 5550438 YP_001436927.1 CDS ESA_00814 NC_009778.1 791810 792685 R KEGG: eci:UTI89_C2768 2.5e-128 amiA; probable N-acetylmuramoyl-L-alanine amidase AmiA precursor K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: nuclear, score: 23; N-acetylmuramoyl-l-alanine amidase I complement(791810..792685) Cronobacter sakazakii ATCC BAA-894 5550382 YP_001436928.1 CDS ESA_00815 NC_009778.1 792756 792884 D Psort location: cytoplasmic, score: 23; hypothetical protein 792756..792884 Cronobacter sakazakii ATCC BAA-894 5550409 YP_001436929.1 CDS ESA_00817 NC_009778.1 792777 793094 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(792777..793094) Cronobacter sakazakii ATCC BAA-894 5550413 YP_001436930.1 CDS ESA_00816 NC_009778.1 793074 793325 D KEGG: eco:b2434 1.6e-37 ypeA; putative acetyltransferase K00680; COG: COG0456 Acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 793074..793325 Cronobacter sakazakii ATCC BAA-894 5550400 YP_001436931.1 CDS ESA_00818 NC_009778.1 793364 793768 R COG: COG3111 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(793364..793768) Cronobacter sakazakii ATCC BAA-894 5550411 YP_001436932.1 CDS ESA_00819 NC_009778.1 793861 794295 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 793861..794295 Cronobacter sakazakii ATCC BAA-894 5550396 YP_001436933.1 CDS ESA_00820 NC_009778.1 794358 794942 D COG: NOG06776 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 794358..794942 Cronobacter sakazakii ATCC BAA-894 5550392 YP_001436934.1 CDS ESA_00821 NC_009778.1 795033 795935 D KEGG: reh:H16_B0946 3.5e-42 predicted iron-dependent peroxidase K00430; COG: COG2837 Predicted iron-dependent peroxidase; Psort location: cytoplasmic, score: 23; hypothetical protein 795033..795935 Cronobacter sakazakii ATCC BAA-894 5550394 YP_001436935.1 CDS ESA_00822 NC_009778.1 796095 797111 D COG: COG4150 ABC-type sulfate transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; thiosulfate transporter subunit 796095..797111 Cronobacter sakazakii ATCC BAA-894 5550354 YP_001436936.1 CDS ESA_00823 NC_009778.1 797111 797941 D KEGG: cyb:CYB_0398 3.0e-29 modB; molybdate ABC transporter, permease protein K02018; COG: COG0555 ABC-type sulfate transport system, permease component; Psort location: endoplasmic reticulum, score: 9; sulfate/thiosulfate transporter subunit 797111..797941 Cronobacter sakazakii ATCC BAA-894 5550387 YP_001436937.1 CDS cysW NC_009778.1 797941 798810 D Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 797941..798810 Cronobacter sakazakii ATCC BAA-894 5550371 YP_001436938.1 CDS ESA_00825 NC_009778.1 798800 799894 D KEGG: sdy:SDY_2618 1.1e-178 cysA; ATP-binding component of sulfate permease A protein K02045; COG: COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; Psort location: cytoplasmic, score: 23; sulfate/thiosulfate transporter subunit 798800..799894 Cronobacter sakazakii ATCC BAA-894 5550381 YP_001436939.1 CDS cysM NC_009778.1 800014 800928 D catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 800014..800928 Cronobacter sakazakii ATCC BAA-894 5550363 YP_001436940.1 CDS ESA_00827 NC_009778.1 800991 801383 R COG: NOG10258 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(800991..801383) Cronobacter sakazakii ATCC BAA-894 5550369 YP_001436941.1 CDS ESA_00828 NC_009778.1 801529 802032 R functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit complement(801529..802032) Cronobacter sakazakii ATCC BAA-894 5550368 YP_001436942.1 CDS ESA_00829 NC_009778.1 802076 803803 R Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase complement(802076..803803) Cronobacter sakazakii ATCC BAA-894 5550258 YP_001436943.1 CDS ESA_00830 NC_009778.1 803847 804104 R KEGG: bci:BCI_0069 1.5e-32 ptsH; phosphocarrier protein HPr K00890; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: cytoplasmic, score: 23; PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr complement(803847..804104) Cronobacter sakazakii ATCC BAA-894 5550362 YP_001436944.1 CDS ESA_00831 NC_009778.1 804488 805459 R CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A complement(804488..805459) Cronobacter sakazakii ATCC BAA-894 5550351 YP_001436945.1 CDS ESA_00832 NC_009778.1 805606 806568 R KEGG: ret:RHE_CH03674 2.8e-06 hypothetical protein K01954; COG: COG2981 Uncharacterized protein involved in cysteine biosynthesis; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(805606..806568) Cronobacter sakazakii ATCC BAA-894 5550352 YP_001436946.1 CDS ESA_00833 NC_009778.1 806598 807557 D interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 806598..807557 Cronobacter sakazakii ATCC BAA-894 5550242 YP_001436947.1 CDS ligA NC_009778.1 807626 809644 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 807626..809644 Cronobacter sakazakii ATCC BAA-894 5548463 YP_001436948.1 CDS ESA_00835 NC_009778.1 809646 809861 D KEGG: cta:CTA_0585 0.00043 dnaQ_2; DNA polymerase III, epsilon chain K02342; COG: COG3530 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 809646..809861 Cronobacter sakazakii ATCC BAA-894 5550007 YP_001436949.1 CDS ESA_00836 NC_009778.1 809942 810277 R COG: NOG12169 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(809942..810277) Cronobacter sakazakii ATCC BAA-894 5550366 YP_001436950.1 CDS gltX NC_009778.1 811267 812682 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 811267..812682 Cronobacter sakazakii ATCC BAA-894 5550491 YP_001436951.1 CDS ESA_00842 NC_009778.1 812708 813097 R COG: NOG09771 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(812708..813097) Cronobacter sakazakii ATCC BAA-894 5550523 YP_001436952.1 CDS ESA_00843 NC_009778.1 813101 813460 R COG: NOG09771 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(813101..813460) Cronobacter sakazakii ATCC BAA-894 5550533 YP_001436953.1 CDS ESA_00846 NC_009778.1 814028 816235 D KEGG: shn:Shewana3_3829 8.8e-19 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2199 FOG: GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 814028..816235 Cronobacter sakazakii ATCC BAA-894 5550530 YP_001436954.1 CDS ESA_00847 NC_009778.1 816278 817462 R COG: COG1972 Nucleoside permease; Psort location: plasma membrane, score: 23; hypothetical protein complement(816278..817462) Cronobacter sakazakii ATCC BAA-894 5550593 YP_001436955.1 CDS ESA_00848 NC_009778.1 817819 819057 D COG: COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; Psort location: plasma membrane, score: 23; manganese transport protein MntH 817819..819057 Cronobacter sakazakii ATCC BAA-894 5550611 YP_001436956.1 CDS ESA_00849 NC_009778.1 819122 819493 R KEGG: ddi:DDB0219950 0.00013 helB2; putative RNA helicase K01529; COG: NOG09770 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(819122..819493) Cronobacter sakazakii ATCC BAA-894 5550582 YP_001436957.1 CDS ESA_00850 NC_009778.1 819614 820603 R KEGG: ret:RHE_CH02454 1.4e-109 probable oxidoreductase protein K05882; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein complement(819614..820603) Cronobacter sakazakii ATCC BAA-894 5550556 YP_001436958.1 CDS ESA_00851 NC_009778.1 820815 822491 D KEGG: stm:STM2405 1.2e-188 indolepyruvate decarboxylase K01568; COG: COG3961 Pyruvate decarboxylase and related THIamine pyrophosphate-requiring enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 820815..822491 Cronobacter sakazakii ATCC BAA-894 5550596 YP_001436959.1 CDS glk NC_009778.1 822645 823610 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 822645..823610 Cronobacter sakazakii ATCC BAA-894 5550626 YP_001436960.1 CDS ESA_00853 NC_009778.1 823646 824377 R KEGG: rru:Rru_A0376 3.0e-20 transcriptional regulator, LytR/AlgR family K07705; COG: COG3279 Response regulator of the LytR/AlgR family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(823646..824377) Cronobacter sakazakii ATCC BAA-894 5550658 YP_001436961.1 CDS ESA_00854 NC_009778.1 824389 826113 R KEGG: ece:Z3645 1.1e-267 putative sensor protein K07704; COG: COG3275 Putative regulator of cell autolysis; Psort location: plasma membrane, score: 23; hypothetical protein complement(824389..826113) Cronobacter sakazakii ATCC BAA-894 5550673 YP_001436962.1 CDS ESA_00855 NC_009778.1 826159 827400 R COG: NOG06762 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(826159..827400) Cronobacter sakazakii ATCC BAA-894 5550693 YP_001436963.1 CDS ESA_00856 NC_009778.1 827641 828882 D KEGG: eco:b2379 5.5e-211 yfdZ; putative PLP-dependent aminotransferase; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: cytoplasmic, score: 23; aminotransferase 827641..828882 Cronobacter sakazakii ATCC BAA-894 5550700 YP_001436964.1 CDS ESA_00857 NC_009778.1 829346 829702 D KEGG: sat:SYN_01359 2.1e-05 mannose-6-phosphate isomerase K01809; COG: COG0662 Mannose-6-phosphate isomerase; Psort location: cytoplasmic, score: 23; hypothetical protein 829346..829702 Cronobacter sakazakii ATCC BAA-894 5550710 YP_001436965.1 CDS ESA_00858 NC_009778.1 829680 830648 R COG: COG0598 Mg2+ and Co2+ transporters; Psort location: cytoplasmic, score: 23; hypothetical protein complement(829680..830648) Cronobacter sakazakii ATCC BAA-894 5552466 YP_001436966.1 CDS ESA_00859 NC_009778.1 830742 831614 R KEGG: shn:Shewana3_3435 2.2e-24 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(830742..831614) Cronobacter sakazakii ATCC BAA-894 5550670 YP_001436967.1 CDS ESA_00860 NC_009778.1 831820 832500 D KEGG: eca:ECA0740 2.4e-73 budA, aldC; alpha-acetolactate decarboxylase K01575; COG: COG3527 Alpha-acetolactate decarboxylase; Psort location: cytoplasmic, score: 23; hypothetical protein 831820..832500 Cronobacter sakazakii ATCC BAA-894 5550704 YP_001436968.1 CDS ESA_00861 NC_009778.1 832522 834201 D catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 832522..834201 Cronobacter sakazakii ATCC BAA-894 5550827 YP_001436969.1 CDS ESA_00862 NC_009778.1 834222 834992 D KEGG: eca:ECA0310 6.3e-107 budC; acetoin reductase K03366; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; acetoin reductase 834222..834992 Cronobacter sakazakii ATCC BAA-894 5550695 YP_001436970.1 CDS ESA_00863 NC_009778.1 835278 835973 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(835278..835973) Cronobacter sakazakii ATCC BAA-894 5550787 YP_001436971.1 CDS ESA_00864 NC_009778.1 836284 836418 D Psort location: nuclear, score: 23; hypothetical protein 836284..836418 Cronobacter sakazakii ATCC BAA-894 5550803 YP_001436972.1 CDS ESA_00865 NC_009778.1 836328 836957 R Psort location: mitochondrial, score: 23; hypothetical protein complement(836328..836957) Cronobacter sakazakii ATCC BAA-894 5550822 YP_001436973.1 CDS ESA_00867 NC_009778.1 837390 838340 R KEGG: bcz:BCZK3485 8.0e-12 fdhC; formate transporter K00122; COG: COG2116 Formate/nitrite family of transporters; Psort location: plasma membrane, score: 23; hypothetical protein complement(837390..838340) Cronobacter sakazakii ATCC BAA-894 5550420 YP_001436974.1 CDS ESA_00869 NC_009778.1 838353 838538 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(838353..838538) Cronobacter sakazakii ATCC BAA-894 5550334 YP_001436975.1 CDS ESA_00868 NC_009778.1 838537 839151 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 838537..839151 Cronobacter sakazakii ATCC BAA-894 5550346 YP_001436976.1 CDS ESA_00870 NC_009778.1 839148 839807 D COG: COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 839148..839807 Cronobacter sakazakii ATCC BAA-894 5548817 YP_001436977.1 CDS ESA_00871 NC_009778.1 839847 840578 D KEGG: vfi:VF1822 2.6e-85 heme chaperone heme-lyase K02195; COG: COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 839847..840578 Cronobacter sakazakii ATCC BAA-894 5549926 YP_001436978.1 CDS ESA_00872 NC_009778.1 840575 840769 D COG: COG3114 Heme exporter protein D; Psort location: cytoplasmic, score: 23; hypothetical protein 840575..840769 Cronobacter sakazakii ATCC BAA-894 5550313 YP_001436979.1 CDS ESA_00873 NC_009778.1 840766 841245 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 840766..841245 Cronobacter sakazakii ATCC BAA-894 5550317 YP_001436980.1 CDS ESA_00874 NC_009778.1 841242 843191 D KEGG: vfi:VF1819 1.2e-229 heme chaperone--apocytochrome heme-lyase K02198; COG: COG1138 Cytochrome c biogenesis factor; Psort location: plasma membrane, score: 23; hypothetical protein 841242..843191 Cronobacter sakazakii ATCC BAA-894 5550323 YP_001436981.1 CDS ESA_00875 NC_009778.1 843188 843745 D KEGG: azo:azo3929 7.6e-31 ccmG; protein disulfide-isomerase K01829; COG: COG0526 Thiol-disulfide isomerase and THIoredoxins; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 843188..843745 Cronobacter sakazakii ATCC BAA-894 5550153 YP_001436982.1 CDS ESA_00876 NC_009778.1 843742 844203 D KEGG: stm:STM4281 1.1e-19 nrfE; putative methylase K04016; COG: COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 843742..844203 Cronobacter sakazakii ATCC BAA-894 5549998 YP_001436983.1 CDS ESA_00877 NC_009778.1 844200 845399 D COG: COG4235 Cytochrome c biogenesis factor; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 844200..845399 Cronobacter sakazakii ATCC BAA-894 5550048 YP_001436984.1 CDS ESA_00878 NC_009778.1 845423 846178 D COG: COG2853 Surface lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 845423..846178 Cronobacter sakazakii ATCC BAA-894 5549885 YP_001436985.1 CDS ESA_00879 NC_009778.1 846304 847683 R COG: COG2067 Long-chain fatty acid transport protein; Psort location: cytoplasmic, score: 23; long-chain fatty acid outer membrane transporter complement(846304..847683) Cronobacter sakazakii ATCC BAA-894 5549955 YP_001436986.1 CDS ESA_00880 NC_009778.1 848024 848308 D COG: COG3691 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 848024..848308 Cronobacter sakazakii ATCC BAA-894 5550061 YP_001436987.1 CDS fadI NC_009778.1 848476 849786 D FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 848476..849786 Cronobacter sakazakii ATCC BAA-894 5550274 YP_001436988.1 CDS fadJ NC_009778.1 849786 851939 D multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 849786..851939 Cronobacter sakazakii ATCC BAA-894 5550271 YP_001436989.1 CDS ESA_00883 NC_009778.1 852144 852632 D KEGG: sty:STY2619 2.7e-67 phosphohistidine phosphatase K08296; COG: COG2062 Phosphohistidine phosphatase SixA; Psort location: endoplasmic reticulum, score: 9; phosphohistidine phosphatase 852144..852632 Cronobacter sakazakii ATCC BAA-894 5550009 YP_001436990.1 CDS ESA_00884 NC_009778.1 852703 853311 R COG: COG2840 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(852703..853311) Cronobacter sakazakii ATCC BAA-894 5550062 YP_001436991.1 CDS ESA_00885 NC_009778.1 853332 854348 D involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 853332..854348 Cronobacter sakazakii ATCC BAA-894 5550198 YP_001436992.1 CDS ESA_00888 NC_009778.1 854329 855618 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(854329..855618) Cronobacter sakazakii ATCC BAA-894 5550248 YP_001436993.1 CDS ESA_00886 NC_009778.1 854413 855498 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 854413..855498 Cronobacter sakazakii ATCC BAA-894 5552472 YP_001436994.1 CDS mepA NC_009778.1 855503 856327 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 855503..856327 Cronobacter sakazakii ATCC BAA-894 5549938 YP_001436995.1 CDS ESA_00889 NC_009778.1 856340 857146 D COG: COG0730 Predicted permeases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 856340..857146 Cronobacter sakazakii ATCC BAA-894 5549952 YP_001436996.1 CDS ESA_00890 NC_009778.1 857146 857691 D COG: COG3101 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 857146..857691 Cronobacter sakazakii ATCC BAA-894 5552422 YP_001436997.1 CDS ESA_00891 NC_009778.1 857720 857998 D COG: NOG13546 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 857720..857998 Cronobacter sakazakii ATCC BAA-894 5552464 YP_001436998.1 CDS mnmC NC_009778.1 858083 860155 R catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase complement(858083..860155) Cronobacter sakazakii ATCC BAA-894 5552397 YP_001436999.1 CDS ESA_00893 NC_009778.1 860253 861470 D FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase I 860253..861470 Cronobacter sakazakii ATCC BAA-894 5552187 YP_001437000.1 CDS ESA_00894 NC_009778.1 862040 864814 D KEGG: pen:PSEEN3027 1.5e-48 serine protease PspB; COG: COG1404 Subtilisin-like serine proteases; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 862040..864814 Cronobacter sakazakii ATCC BAA-894 5552372 YP_001437001.1 CDS flk NC_009778.1 864868 865875 R in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator complement(864868..865875) Cronobacter sakazakii ATCC BAA-894 5552347 YP_001437002.1 CDS ESA_00896 NC_009778.1 865995 867131 D KEGG: sec:SC2372 3.0e-171 pdxB; erythronate-4-phosphate dehyrogenase K03473; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 865995..867131 Cronobacter sakazakii ATCC BAA-894 5552333 YP_001437003.1 CDS ESA_00897 NC_009778.1 867198 868211 D KEGG: eci:UTI89_C2604 1.6e-149 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: cytoplasmic, score: 23; putative semialdehyde dehydrogenase 867198..868211 Cronobacter sakazakii ATCC BAA-894 5552290 YP_001437004.1 CDS truA NC_009778.1 868211 869023 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 868211..869023 Cronobacter sakazakii ATCC BAA-894 5552299 YP_001437005.1 CDS ESA_00899 NC_009778.1 869049 869708 D KEGG: lsl:LSL_1322 3.7e-15 alkaline phosphatase K01077; COG: COG0586 Uncharacterized membrane-associated protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 869049..869708 Cronobacter sakazakii ATCC BAA-894 5552275 YP_001437006.1 CDS ESA_00900 NC_009778.1 869805 870779 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 869805..870779 Cronobacter sakazakii ATCC BAA-894 5552283 YP_001437007.1 CDS ESA_00901 NC_009778.1 870823 872118 D KEGG: sty:STY2596 5.7e-177 folC; folylpolyglutamate synthase K01927:K01930; COG: COG0285 Folylpolyglutamate synthase; Psort location: cytoplasmic, score: 23; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 870823..872118 Cronobacter sakazakii ATCC BAA-894 5552268 YP_001437008.1 CDS ESA_00902 NC_009778.1 872108 872830 D KEGG: pfo:Pfl_1900 9.8e-09 argininosuccinate synthase K03749; COG: COG3147 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 872108..872830 Cronobacter sakazakii ATCC BAA-894 5552219 YP_001437009.1 CDS ESA_00903 NC_009778.1 873063 873548 D membrane protein required for colicin V production; colicin V production protein 873063..873548 Cronobacter sakazakii ATCC BAA-894 5552242 YP_001437010.1 CDS ESA_00904 NC_009778.1 873588 875105 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 873588..875105 Cronobacter sakazakii ATCC BAA-894 5552213 YP_001437011.1 CDS ESA_00905 NC_009778.1 875217 875786 D catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 875217..875786 Cronobacter sakazakii ATCC BAA-894 5552243 YP_001437012.1 CDS ESA_00906 NC_009778.1 876063 876845 D KEGG: bur:Bcep18194_A4695 9.0e-28 ABC polar amino acid transporter, periplasmic ligand binding protein K01713; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 876063..876845 Cronobacter sakazakii ATCC BAA-894 5552218 YP_001437013.1 CDS ESA_00907 NC_009778.1 877069 877863 D KEGG: bur:Bcep18194_A4695 1.3e-28 ABC polar amino acid transporter, periplasmic ligand binding protein K01713; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 877069..877863 Cronobacter sakazakii ATCC BAA-894 5552169 YP_001437014.1 CDS ESA_00909 NC_009778.1 877162 877938 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(877162..877938) Cronobacter sakazakii ATCC BAA-894 5551991 YP_001437015.1 CDS ESA_00908 NC_009778.1 877937 878623 D KEGG: sma:SAV6546 2.4e-20 putative ABC transporter permease K02028; COG: COG4215 ABC-type arginine transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 877937..878623 Cronobacter sakazakii ATCC BAA-894 5552226 YP_001437016.1 CDS ESA_00910 NC_009778.1 878620 879336 D KEGG: sma:SAV6546 3.6e-24 putative ABC transporter permease K02028; COG: COG4160 ABC-type arginine/histidine transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 878620..879336 Cronobacter sakazakii ATCC BAA-894 5552011 YP_001437017.1 CDS ESA_00911 NC_009778.1 879347 880120 D KEGG: sdy:SDY_2505 6.1e-125 hisP; ATP-binding component of histidine transport K02028; COG: COG4598 ABC-type histidine transport system, ATPase component; Psort location: cytoplasmic, score: 23; histidine/lysine/arginine/ornithine transporter subunit 879347..880120 Cronobacter sakazakii ATCC BAA-894 5552055 YP_001437018.1 CDS ESA_00912 NC_009778.1 880148 880792 R COG: NOG23433 non supervised orthologous group; Psort location: cytoskeletal, score: 9; hypothetical protein complement(880148..880792) Cronobacter sakazakii ATCC BAA-894 5552084 YP_001437019.1 CDS ESA_00913 NC_009778.1 880785 881489 R COG: NOG34653 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(880785..881489) Cronobacter sakazakii ATCC BAA-894 5552173 YP_001437020.1 CDS ESA_00914 NC_009778.1 881629 882531 R KEGG: ava:Ava_0206 1.8e-52 hypothetical protein; COG: COG1090 Predicted nucleoside-diphosphate sugar epimerase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(881629..882531) Cronobacter sakazakii ATCC BAA-894 5552191 YP_001437021.1 CDS ESA_00915 NC_009778.1 882673 883299 R KEGG: eci:UTI89_C2586 8.8e-85 yfcG; putative S-transferase K00799; COG: COG0625 glutathione S-transferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(882673..883299) Cronobacter sakazakii ATCC BAA-894 5552192 YP_001437022.1 CDS ESA_00916 NC_009778.1 883315 884088 D KEGG: eci:UTI89_C2585 9.1e-83 yfcF; hypothetical protein K00799; COG: COG0625 glutathione S-transferase; Psort location: cytoplasmic, score: 23; hypothetical protein 883315..884088 Cronobacter sakazakii ATCC BAA-894 5552107 YP_001437023.1 CDS ESA_00917 NC_009778.1 884148 884699 D KEGG: eci:UTI89_C2584 3.6e-72 yfcE; hypothetical protein; COG: COG0622 Predicted phosphoesterase; Psort location: cytoplasmic, score: 23; hypothetical protein 884148..884699 Cronobacter sakazakii ATCC BAA-894 5552210 YP_001437024.1 CDS ESA_00918 NC_009778.1 884754 885338 D KEGG: ssn:SSO_2356 2.1e-76 putative regulator; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 884754..885338 Cronobacter sakazakii ATCC BAA-894 5552284 YP_001437025.1 CDS ESA_00919 NC_009778.1 885394 885945 R COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(885394..885945) Cronobacter sakazakii ATCC BAA-894 5552355 YP_001437026.1 CDS ESA_00920 NC_009778.1 886255 886599 D KEGG: bcz:BCZK3497 4.0e-09 adaA; transcriptional regulator, AraC family K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: nuclear, score: 23; hypothetical protein 886255..886599 Cronobacter sakazakii ATCC BAA-894 5548500 YP_001437027.1 CDS ESA_00921 NC_009778.1 886668 886919 D COG: NOG15356 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 886668..886919 Cronobacter sakazakii ATCC BAA-894 5550312 YP_001437028.1 CDS ESA_00922 NC_009778.1 886985 889108 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(886985..889108) Cronobacter sakazakii ATCC BAA-894 5548519 YP_001437029.1 CDS ESA_00923 NC_009778.1 889206 890408 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(889206..890408) Cronobacter sakazakii ATCC BAA-894 5549979 YP_001437030.1 CDS ESA_00924 NC_009778.1 890743 891198 D COG: COG3092 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 890743..891198 Cronobacter sakazakii ATCC BAA-894 5548336 YP_001437031.1 CDS ESA_00925 NC_009778.1 891285 891779 D COG: COG3013 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 891285..891779 Cronobacter sakazakii ATCC BAA-894 5548503 YP_001437032.1 CDS ESA_00926 NC_009778.1 891792 892451 D KEGG: eci:UTI89_C2575 1.3e-81 yfbT; protein YfbT K01112; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: cytoplasmic, score: 23; putative phosphatase 891792..892451 Cronobacter sakazakii ATCC BAA-894 5548104 YP_001437033.1 CDS ESA_00927 NC_009778.1 892536 894386 D COG: COG0471 Di- and tricarboxylate transporters; Psort location: plasma membrane, score: 23; hypothetical protein 892536..894386 Cronobacter sakazakii ATCC BAA-894 5548129 YP_001437034.1 CDS ESA_00928 NC_009778.1 894392 894991 R KEGG: sdy:SDY_2487 2.4e-91 putative alpha helix protein K08722; COG: COG1896 Predicted hydrolases of HD superfamily; Psort location: mitochondrial, score: 23; hypothetical protein complement(894392..894991) Cronobacter sakazakii ATCC BAA-894 5548206 YP_001437035.1 CDS ESA_00929 NC_009778.1 895072 896286 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT complement(895072..896286) Cronobacter sakazakii ATCC BAA-894 5548109 YP_001437036.1 CDS ESA_00930 NC_009778.1 897238 898173 D KEGG: shn:Shewana3_3435 0.00059 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 897238..898173 Cronobacter sakazakii ATCC BAA-894 5548115 YP_001437037.1 CDS ESA_00931 NC_009778.1 898259 898405 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(898259..898405) Cronobacter sakazakii ATCC BAA-894 5548413 YP_001437038.1 CDS ESA_00932 NC_009778.1 898792 899241 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 898792..899241 Cronobacter sakazakii ATCC BAA-894 5548454 YP_001437039.1 CDS ESA_00933 NC_009778.1 899257 899931 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 899257..899931 Cronobacter sakazakii ATCC BAA-894 5548395 YP_001437040.1 CDS ESA_00934 NC_009778.1 900019 901830 D NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 900019..901830 Cronobacter sakazakii ATCC BAA-894 5548360 YP_001437041.1 CDS ESA_00935 NC_009778.1 901833 902333 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 901833..902333 Cronobacter sakazakii ATCC BAA-894 5548137 YP_001437042.1 CDS ESA_00936 NC_009778.1 902330 903667 D shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 902330..903667 Cronobacter sakazakii ATCC BAA-894 5551714 YP_001437043.1 CDS ESA_00937 NC_009778.1 903713 906448 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 903713..906448 Cronobacter sakazakii ATCC BAA-894 5552350 YP_001437044.1 CDS ESA_00938 NC_009778.1 906445 907425 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 906445..907425 Cronobacter sakazakii ATCC BAA-894 5552247 YP_001437045.1 CDS ESA_00939 NC_009778.1 907440 907982 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 907440..907982 Cronobacter sakazakii ATCC BAA-894 5552135 YP_001437046.1 CDS ESA_00940 NC_009778.1 907993 908556 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 907993..908556 Cronobacter sakazakii ATCC BAA-894 5552132 YP_001437047.1 CDS ESA_00941 NC_009778.1 908553 908855 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 908553..908855 Cronobacter sakazakii ATCC BAA-894 5549769 YP_001437048.1 CDS ESA_00942 NC_009778.1 908852 910690 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 908852..910690 Cronobacter sakazakii ATCC BAA-894 5549817 YP_001437049.1 CDS ESA_00943 NC_009778.1 910846 912375 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 910846..912375 Cronobacter sakazakii ATCC BAA-894 5549440 YP_001437050.1 CDS ESA_00944 NC_009778.1 912382 913839 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 912382..913839 Cronobacter sakazakii ATCC BAA-894 5549710 YP_001437051.1 CDS ESA_00945 NC_009778.1 913892 914806 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(913892..914806) Cronobacter sakazakii ATCC BAA-894 5549744 YP_001437052.1 CDS ESA_00946 NC_009778.1 914880 915350 D KEGG: vfi:VF0317 1.4e-31 acetyltransferase K02348; COG: COG2153 Predicted acyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 914880..915350 Cronobacter sakazakii ATCC BAA-894 5548291 YP_001437053.1 CDS ESA_00947 NC_009778.1 915379 915711 D COG: COG4575 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 915379..915711 Cronobacter sakazakii ATCC BAA-894 5548212 YP_001437054.1 CDS ESA_00948 NC_009778.1 915815 917104 D KEGG: sec:SC2310 4.6e-111 menF; isochorismate synthase (isochorismate hydroxymutase 2), menaquinone biosynthesis K02552; COG: COG1169 Isochorismate synthase; Psort location: cytoplasmic, score: 23; hypothetical protein 915815..917104 Cronobacter sakazakii ATCC BAA-894 5548112 YP_001437055.1 CDS ESA_00949 NC_009778.1 917189 918856 D SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 917189..918856 Cronobacter sakazakii ATCC BAA-894 5549516 YP_001437056.1 CDS ESA_00950 NC_009778.1 918856 919620 D KEGG: sbo:SBO_2300 1.7e-65 yfbB; putative enzyme K08680; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein 918856..919620 Cronobacter sakazakii ATCC BAA-894 5549662 YP_001437057.1 CDS ESA_00951 NC_009778.1 919633 920490 D catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 919633..920490 Cronobacter sakazakii ATCC BAA-894 5549495 YP_001437058.1 CDS ESA_00952 NC_009778.1 920490 921455 D catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 920490..921455 Cronobacter sakazakii ATCC BAA-894 5549461 YP_001437059.1 CDS ESA_00953 NC_009778.1 921491 922846 D KEGG: stt:t0558 1.5e-151 menE; O-succinylbenzoic acid-CoA ligase K01911; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: mitochondrial, score: 23; O-succinylbenzoic acid--CoA ligase 921491..922846 Cronobacter sakazakii ATCC BAA-894 5552393 YP_001437060.1 CDS ESA_00954 NC_009778.1 922823 923446 R COG: COG3647 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(922823..923446) Cronobacter sakazakii ATCC BAA-894 5552419 YP_001437061.1 CDS ESA_00955 NC_009778.1 923553 925070 R KEGG: mka:MK1013 0.00084 ntpK; archaeal/vacuolar-type H+-ATPase subunit K K02124; COG: COG3333 Uncharacterized protein conserved in bacteria; Psort location: plasma membrane, score: 23; hypothetical protein complement(923553..925070) Cronobacter sakazakii ATCC BAA-894 5552331 YP_001437062.1 CDS ESA_00956 NC_009778.1 925082 925513 R COG: NOG11450 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(925082..925513) Cronobacter sakazakii ATCC BAA-894 5551538 YP_001437063.1 CDS ESA_00957 NC_009778.1 925528 926520 R COG: COG3181 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(925528..926520) Cronobacter sakazakii ATCC BAA-894 5551493 YP_001437064.1 CDS ESA_00958 NC_009778.1 926642 927322 D KEGG: rha:RHA1_ro05622 3.8e-36 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: cytoplasmic, score: 23; hypothetical protein 926642..927322 Cronobacter sakazakii ATCC BAA-894 5551248 YP_001437065.1 CDS ESA_00959 NC_009778.1 927303 928739 D KEGG: stt:t2678 7.2e-161 tctE; putative two-component system sensor kinase K07649; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 927303..928739 Cronobacter sakazakii ATCC BAA-894 5552032 YP_001437066.1 CDS ESA_00960 NC_009778.1 928905 929423 D COG: NOG08732 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 928905..929423 Cronobacter sakazakii ATCC BAA-894 5552437 YP_001437067.1 CDS ESA_00961 NC_009778.1 929517 930713 D KEGG: hsa:80308 6.6e-08 FLAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae) K00953; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: cytoplasmic, score: 23; competence damage-inducible protein A 929517..930713 Cronobacter sakazakii ATCC BAA-894 5548382 YP_001437068.1 CDS ESA_00962 NC_009778.1 930858 931034 R Psort location: mitochondrial, score: 23; hypothetical protein complement(930858..931034) Cronobacter sakazakii ATCC BAA-894 5548303 YP_001437069.1 CDS glpT NC_009778.1 931050 932402 D catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 931050..932402 Cronobacter sakazakii ATCC BAA-894 5548411 YP_001437070.1 CDS glpQ NC_009778.1 932412 933470 D hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 932412..933470 Cronobacter sakazakii ATCC BAA-894 5548434 YP_001437071.1 CDS ESA_00965 NC_009778.1 933561 933815 R plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin YfaE complement(933561..933815) Cronobacter sakazakii ATCC BAA-894 5548286 YP_001437072.1 CDS nrdB NC_009778.1 933817 934947 R B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta complement(933817..934947) Cronobacter sakazakii ATCC BAA-894 5548399 YP_001437073.1 CDS ESA_00967 NC_009778.1 935122 937407 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(935122..937407) Cronobacter sakazakii ATCC BAA-894 5548254 YP_001437074.1 CDS ESA_00968 NC_009778.1 937760 938491 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(937760..938491) Cronobacter sakazakii ATCC BAA-894 5548353 YP_001437075.1 CDS ESA_00969 NC_009778.1 938651 941287 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 938651..941287 Cronobacter sakazakii ATCC BAA-894 5548107 YP_001437076.1 CDS ESA_00970 NC_009778.1 941401 944322 D KEGG: sec:SC2274 0. rcsC; sensory histidine kinase in two-component regulatory system with RcsB, regulates colanic capsule biosynthesis K07677; COG: COG0784 FOG: CheY-like receiver; Psort location: endoplasmic reticulum, score: 9; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 941401..944322 Cronobacter sakazakii ATCC BAA-894 5548274 YP_001437077.1 CDS ESA_00971 NC_009778.1 944494 945144 R two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB complement(944494..945144) Cronobacter sakazakii ATCC BAA-894 5548216 YP_001437078.1 CDS ESA_00972 NC_009778.1 945161 947833 R KEGG: stm:STM2269 0. yojN; putative sensor/kinase in regulatory system K07676; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; phosphotransfer intermediate protein in two-component regulatory system with RcsBC complement(945161..947833) Cronobacter sakazakii ATCC BAA-894 5548452 YP_001437079.1 CDS ESA_00974 NC_009778.1 948652 949791 D allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 948652..949791 Cronobacter sakazakii ATCC BAA-894 5548456 YP_001437080.1 CDS ESA_00975 NC_009778.1 949933 950919 D catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 949933..950919 Cronobacter sakazakii ATCC BAA-894 5548479 YP_001437081.1 CDS ESA_00976 NC_009778.1 950992 952056 D KEGG: ecc:c2754 7.5e-111 ada; ADA regulatory protein K00567; COG: COG0350 Methylated DNA-protein cysteine methyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 950992..952056 Cronobacter sakazakii ATCC BAA-894 5548307 YP_001437082.1 CDS ESA_00977 NC_009778.1 952056 952700 D COG: COG3145 Alkylated DNA repair protein; Psort location: cytoplasmic, score: 23; hypothetical protein 952056..952700 Cronobacter sakazakii ATCC BAA-894 5552004 YP_001437083.1 CDS ESA_00978 NC_009778.1 952779 954425 D efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding component 952779..954425 Cronobacter sakazakii ATCC BAA-894 5552396 YP_001437084.1 CDS ESA_00979 NC_009778.1 954501 955994 R KEGG: hpa:HPAG1_0231 3.6e-63 putative sulfate permease K01672; COG: COG0659 Sulfate permease and related transporters (MFS superfamily); Psort location: plasma membrane, score: 23; hypothetical protein complement(954501..955994) Cronobacter sakazakii ATCC BAA-894 5548323 YP_001437085.1 CDS ESA_00980 NC_009778.1 956100 956312 R KEGG: ava:Ava_3150 8.3e-06 lysS; lysyl-tRNA synthetase K04567; COG: NOG22391 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(956100..956312) Cronobacter sakazakii ATCC BAA-894 5548155 YP_001437086.1 CDS ESA_00981 NC_009778.1 956451 957212 R COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(956451..957212) Cronobacter sakazakii ATCC BAA-894 5548341 YP_001437087.1 CDS ESA_00982 NC_009778.1 957262 958257 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: golgi, score: 9; hypothetical protein complement(957262..958257) Cronobacter sakazakii ATCC BAA-894 5548294 YP_001437088.1 CDS ESA_00983 NC_009778.1 958360 959985 R KEGG: eci:UTI89_C4946 3.7e-08 putative member of ShlA/HecA/FhaA exoprotein family; COG: COG5295 Autotransporter adhesin; Psort location: cytoplasmic, score: 23; hypothetical protein complement(958360..959985) Cronobacter sakazakii ATCC BAA-894 5548366 YP_001437089.1 CDS ESA_00984 NC_009778.1 959982 960218 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(959982..960218) Cronobacter sakazakii ATCC BAA-894 5548443 YP_001437090.1 CDS ESA_00985 NC_009778.1 960239 962293 R KEGG: chu:CHU_2528 5.0e-09 CHU large protein; uncharacterized K01238; COG: COG5295 Autotransporter adhesin; Psort location: cytoplasmic, score: 23; hypothetical protein complement(960239..962293) Cronobacter sakazakii ATCC BAA-894 5548096 YP_001437091.1 CDS ESA_00986 NC_009778.1 962430 963449 R KEGG: mxa:MXAN_3564 0.00017 peptidase, M36 (fungalysin) family K01423; COG: COG5295 Autotransporter adhesin; Psort location: cytoplasmic, score: 23; hypothetical protein complement(962430..963449) Cronobacter sakazakii ATCC BAA-894 5548449 YP_001437092.1 CDS ESA_00987 NC_009778.1 963828 966911 R KEGG: chu:CHU_2852 5.5e-31 CHU large protein; candidate b-glycosidase, glycoside hydrolase family 8 protein K01238; COG: COG5295 Autotransporter adhesin; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(963828..966911) Cronobacter sakazakii ATCC BAA-894 5548159 YP_001437093.1 CDS ESA_00988 NC_009778.1 967688 968038 D Psort location: cytoplasmic, score: 23; hypothetical protein 967688..968038 Cronobacter sakazakii ATCC BAA-894 5551984 YP_001437094.1 CDS ESA_00989 NC_009778.1 968155 969045 R KEGG: shn:Shewana3_3435 0.0073 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(968155..969045) Cronobacter sakazakii ATCC BAA-894 5548126 YP_001437095.1 CDS ESA_00990 NC_009778.1 969835 971019 R COG: COG0582 Integrase; Psort location: nuclear, score: 23; hypothetical protein complement(969835..971019) Cronobacter sakazakii ATCC BAA-894 5548255 YP_001437096.1 CDS ESA_00991 NC_009778.1 971021 971230 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(971021..971230) Cronobacter sakazakii ATCC BAA-894 5548142 YP_001437097.1 CDS ESA_00992 NC_009778.1 971269 971871 R KEGG: sbo:SBO_0976 1.4e-52 putative exodeoxyribonuclease VIII K01146; COG: NOG06785 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(971269..971871) Cronobacter sakazakii ATCC BAA-894 5548117 YP_001437098.1 CDS ESA_00993 NC_009778.1 971872 972192 R Psort location: nuclear, score: 23; hypothetical protein complement(971872..972192) Cronobacter sakazakii ATCC BAA-894 5548141 YP_001437099.1 CDS ESA_00994 NC_009778.1 972185 972622 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(972185..972622) Cronobacter sakazakii ATCC BAA-894 5548481 YP_001437100.1 CDS ESA_00995 NC_009778.1 972619 973101 R KEGG: spi:MGAS10750_Spy0587 5.4e-37 methyltransferase K00599; COG: NOG11045 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(972619..973101) Cronobacter sakazakii ATCC BAA-894 5548211 YP_001437101.1 CDS ESA_00996 NC_009778.1 973094 973294 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(973094..973294) Cronobacter sakazakii ATCC BAA-894 5548176 YP_001437102.1 CDS ESA_00997 NC_009778.1 973435 974175 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(973435..974175) Cronobacter sakazakii ATCC BAA-894 5548099 YP_001437103.1 CDS ESA_00998 NC_009778.1 974256 975185 R COG: COG2974 DNA recombination-dependent growth factor C; Psort location: cytoplasmic, score: 23; hypothetical protein complement(974256..975185) Cronobacter sakazakii ATCC BAA-894 5548240 YP_001437104.1 CDS ESA_00999 NC_009778.1 975781 976017 D COG: NOG31115 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 975781..976017 Cronobacter sakazakii ATCC BAA-894 5548289 YP_001437105.1 CDS ESA_01000 NC_009778.1 975985 976311 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(975985..976311) Cronobacter sakazakii ATCC BAA-894 5548163 YP_001437106.1 CDS ESA_01001 NC_009778.1 976446 977351 D KEGG: chu:CHU_1313 9.2e-05 ligA; DNA ligase K01972; COG: NOG13955 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 976446..977351 Cronobacter sakazakii ATCC BAA-894 5550294 YP_001437107.1 CDS ESA_01002 NC_009778.1 977343 978032 R KEGG: afu:AF2118 0.00021 guaB-2; IMP dehydrogenase K00088; COG: COG2932 Predicted transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(977343..978032) Cronobacter sakazakii ATCC BAA-894 5548185 YP_001437108.1 CDS ESA_01003 NC_009778.1 978168 978389 D COG: COG3381 Uncharacterized component of anaerobic dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 978168..978389 Cronobacter sakazakii ATCC BAA-894 5548186 YP_001437109.1 CDS ESA_01004 NC_009778.1 978440 978991 D COG: NOG27757 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 978440..978991 Cronobacter sakazakii ATCC BAA-894 5548100 YP_001437110.1 CDS ESA_01005 NC_009778.1 979158 979325 D Psort location: cytoplasmic, score: 23; hypothetical protein 979158..979325 Cronobacter sakazakii ATCC BAA-894 5548327 YP_001437111.1 CDS ESA_01006 NC_009778.1 979322 979585 D COG: COG4626 Phage terminase-like protein, large subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 979322..979585 Cronobacter sakazakii ATCC BAA-894 5548241 YP_001437112.1 CDS ESA_01007 NC_009778.1 979337 979786 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(979337..979786) Cronobacter sakazakii ATCC BAA-894 5548381 YP_001437113.1 CDS ESA_01008 NC_009778.1 979861 980217 D COG: NOG18073 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 979861..980217 Cronobacter sakazakii ATCC BAA-894 5548404 YP_001437114.1 CDS ESA_01009 NC_009778.1 980214 980450 D Psort location: nuclear, score: 23; hypothetical protein 980214..980450 Cronobacter sakazakii ATCC BAA-894 5552336 YP_001437115.1 CDS ESA_01010 NC_009778.1 980450 981628 D KEGG: sac:SACOL0346 4.0e-13 prophage L54a, N-6-adenine-methyltransferase K00571; COG: NOG18143 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 980450..981628 Cronobacter sakazakii ATCC BAA-894 5548387 YP_001437116.1 CDS ESA_01011 NC_009778.1 981625 981954 D KEGG: ece:Z5642 2.0e-14 lexA; regulator for SOS(LexA) regulon K01356; COG: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Psort location: nuclear, score: 23; hypothetical protein 981625..981954 Cronobacter sakazakii ATCC BAA-894 5548313 YP_001437117.1 CDS ESA_01012 NC_009778.1 981951 982334 D KEGG: eci:UTI89_C1478 2.8e-17 endodeoxyribonuclease RusA (Holliday junction resolvase) K01160; COG: COG4570 Holliday junction resolvase; Psort location: cytoplasmic, score: 23; hypothetical protein 981951..982334 Cronobacter sakazakii ATCC BAA-894 5548400 YP_001437118.1 CDS ESA_01013 NC_009778.1 982338 983075 D COG: COG3645 Uncharacterized phage-encoded protein; Psort location: cytoplasmic, score: 23; hypothetical protein 982338..983075 Cronobacter sakazakii ATCC BAA-894 5548337 YP_001437119.1 CDS ESA_01014 NC_009778.1 983108 984121 D Psort location: cytoplasmic, score: 23; hypothetical protein 983108..984121 Cronobacter sakazakii ATCC BAA-894 5548426 YP_001437120.1 CDS ESA_01015 NC_009778.1 984140 984898 D COG: NOG09845 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 984140..984898 Cronobacter sakazakii ATCC BAA-894 5548321 YP_001437121.1 CDS ESA_01016 NC_009778.1 985248 985736 D COG: NOG18678 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 985248..985736 Cronobacter sakazakii ATCC BAA-894 5548253 YP_001437122.1 CDS ESA_01017 NC_009778.1 985879 986259 D COG: NOG37752 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 985879..986259 Cronobacter sakazakii ATCC BAA-894 5548472 YP_001437123.1 CDS ESA_01018 NC_009778.1 986246 986530 D COG: NOG23011 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 986246..986530 Cronobacter sakazakii ATCC BAA-894 5548166 YP_001437124.1 CDS ESA_01019 NC_009778.1 986527 987150 D KEGG: cvi:CV0024 5.5e-07 probable hydroxyethylTHIazole kinase K00878; COG: COG3179 Predicted chitinase; Psort location: cytoplasmic, score: 23; hypothetical protein 986527..987150 Cronobacter sakazakii ATCC BAA-894 5548237 YP_001437125.1 CDS ESA_01020 NC_009778.1 987150 987614 D KEGG: ece:Z1798 6.8e-30 putative endopeptidase of prophage CP-933N K01423; COG: NOG19968 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 987150..987614 Cronobacter sakazakii ATCC BAA-894 5548168 YP_001437126.1 CDS ESA_01021 NC_009778.1 987913 988062 D Psort location: nuclear, score: 23; hypothetical protein 987913..988062 Cronobacter sakazakii ATCC BAA-894 5548467 YP_001437127.1 CDS ESA_01022 NC_009778.1 988011 988403 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(988011..988403) Cronobacter sakazakii ATCC BAA-894 5548447 YP_001437128.1 CDS ESA_01023 NC_009778.1 988484 988702 D Psort location: cytoplasmic, score: 23; hypothetical protein 988484..988702 Cronobacter sakazakii ATCC BAA-894 5548501 YP_001437129.1 CDS ESA_01024 NC_009778.1 989018 989338 D COG: COG3747 Phage terminase, small subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 989018..989338 Cronobacter sakazakii ATCC BAA-894 5548279 YP_001437130.1 CDS ESA_01025 NC_009778.1 989338 991095 D COG: COG4626 Phage terminase-like protein, large subunit; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 989338..991095 Cronobacter sakazakii ATCC BAA-894 5548312 YP_001437131.1 CDS ESA_01026 NC_009778.1 991095 992399 D COG: COG4695 Phage-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein 991095..992399 Cronobacter sakazakii ATCC BAA-894 5548276 YP_001437132.1 CDS ESA_01027 NC_009778.1 992408 993262 D KEGG: nwi:Nwi_1543 1.4e-61 peptidase S14, ClpP K01358; COG: COG0740 Protease subunit of ATP-dependent Clp proteases; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 992408..993262 Cronobacter sakazakii ATCC BAA-894 5548234 YP_001437133.1 CDS ESA_01028 NC_009778.1 993276 994496 D KEGG: rxy:Rxyl_1642 0.0065 ATP synthase F0, B subunit K02109; COG: NOG07926 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 993276..994496 Cronobacter sakazakii ATCC BAA-894 5552194 YP_001437134.1 CDS ESA_01029 NC_009778.1 994550 994732 D Psort location: cytoplasmic, score: 23; hypothetical protein 994550..994732 Cronobacter sakazakii ATCC BAA-894 5552421 YP_001437135.1 CDS ESA_01030 NC_009778.1 994742 995068 D COG: NOG24115 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 994742..995068 Cronobacter sakazakii ATCC BAA-894 5551988 YP_001437136.1 CDS ESA_01031 NC_009778.1 995065 995406 D COG: COG5614 Bacteriophage head-tail adaptor; Psort location: mitochondrial, score: 23; hypothetical protein 995065..995406 Cronobacter sakazakii ATCC BAA-894 5548446 YP_001437137.1 CDS ESA_01032 NC_009778.1 995403 995852 D Psort location: nuclear, score: 23; hypothetical protein 995403..995852 Cronobacter sakazakii ATCC BAA-894 5548436 YP_001437138.1 CDS ESA_01033 NC_009778.1 995849 996178 D Psort location: cytoplasmic, score: 23; hypothetical protein 995849..996178 Cronobacter sakazakii ATCC BAA-894 5548260 YP_001437139.1 CDS ESA_01034 NC_009778.1 996226 996681 D Psort location: nuclear, score: 23; hypothetical protein 996226..996681 Cronobacter sakazakii ATCC BAA-894 5548139 YP_001437140.1 CDS ESA_01035 NC_009778.1 996783 997127 D Psort location: cytoplasmic, score: 23; hypothetical protein 996783..997127 Cronobacter sakazakii ATCC BAA-894 5548487 YP_001437141.1 CDS ESA_01037 NC_009778.1 997049 997444 R Psort location: nuclear, score: 23; hypothetical protein complement(997049..997444) Cronobacter sakazakii ATCC BAA-894 5552435 YP_001437142.1 CDS ESA_01036 NC_009778.1 997151 997420 D KEGG: ddi:DDB0188427 0.0013 hypothetical protein K01778; Psort location: cytoplasmic, score: 23; hypothetical protein 997151..997420 Cronobacter sakazakii ATCC BAA-894 5548401 YP_001437143.1 CDS ESA_01038 NC_009778.1 997512 997850 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 997512..997850 Cronobacter sakazakii ATCC BAA-894 5548138 YP_001437144.1 CDS ESA_01039 NC_009778.1 997911 1001441 D KEGG: eci:UTI89_C5128 1.3e-35 putative tail length tape measure protein precursor K00924; COG: COG5281 Phage-related minor tail protein; Psort location: cytoplasmic, score: 23; hypothetical protein 997911..1001441 Cronobacter sakazakii ATCC BAA-894 5548244 YP_001437145.1 CDS ESA_01040 NC_009778.1 1001487 1001825 D COG: COG4718 Phage-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1001487..1001825 Cronobacter sakazakii ATCC BAA-894 5548368 YP_001437146.1 CDS ESA_01041 NC_009778.1 1001832 1002584 D COG: COG4672 Phage-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1001832..1002584 Cronobacter sakazakii ATCC BAA-894 5548101 YP_001437147.1 CDS ESA_01042 NC_009778.1 1002587 1003291 D COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: cytoplasmic, score: 23; hypothetical protein 1002587..1003291 Cronobacter sakazakii ATCC BAA-894 5548462 YP_001437148.1 CDS ESA_01043 NC_009778.1 1003288 1003884 D COG: COG4723 Phage-related protein, tail component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1003288..1003884 Cronobacter sakazakii ATCC BAA-894 5548464 YP_001437149.1 CDS ESA_01044 NC_009778.1 1003934 1007095 D COG: COG4733 Phage-related protein, tail component; Psort location: cytoplasmic, score: 23; hypothetical protein 1003934..1007095 Cronobacter sakazakii ATCC BAA-894 5552356 YP_001437150.1 CDS ESA_01045 NC_009778.1 1007382 1008032 D Psort location: cytoplasmic, score: 23; hypothetical protein 1007382..1008032 Cronobacter sakazakii ATCC BAA-894 5548239 YP_001437151.1 CDS ESA_01046 NC_009778.1 1008970 1009551 D COG: COG5525 Bacteriophage tail assembly protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1008970..1009551 Cronobacter sakazakii ATCC BAA-894 5548162 YP_001437152.1 CDS ESA_01048 NC_009778.1 1010061 1011824 R KEGG: aha:AHA_1664 4.1e-103 putative sulfatase; COG: COG3083 Predicted hydrolase of alkaline phosphatase superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1010061..1011824) Cronobacter sakazakii ATCC BAA-894 5548397 YP_001437153.1 CDS ESA_01049 NC_009778.1 1011844 1012071 R COG: COG3082 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(1011844..1012071) Cronobacter sakazakii ATCC BAA-894 5548127 YP_001437154.1 CDS ESA_01050 NC_009778.1 1012206 1013210 D COG: COG3081 Nucleoid-associated protein; Psort location: cytoplasmic, score: 23; nucleoid-associated protein NdpA 1012206..1013210 Cronobacter sakazakii ATCC BAA-894 5548242 YP_001437155.1 CDS ESA_01051 NC_009778.1 1013311 1013595 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(1013311..1013595) Cronobacter sakazakii ATCC BAA-894 5551792 YP_001437156.1 CDS ESA_01052 NC_009778.1 1013722 1015482 R KEGG: eci:UTI89_C2461 1.8e-292 yejH; hypothetical protein YejH K01529; COG: COG1061 DNA or RNA helicases of superfamily II; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1013722..1015482) Cronobacter sakazakii ATCC BAA-894 5552285 YP_001437157.1 CDS ESA_01054 NC_009778.1 1015503 1016255 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1015503..1016255) Cronobacter sakazakii ATCC BAA-894 5548094 YP_001437158.1 CDS ESA_01053 NC_009778.1 1015653 1016360 D catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 1015653..1016360 Cronobacter sakazakii ATCC BAA-894 5548114 YP_001437159.1 CDS ESA_01055 NC_009778.1 1016376 1017572 D Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 1016376..1017572 Cronobacter sakazakii ATCC BAA-894 5552439 YP_001437160.1 CDS ESA_01056 NC_009778.1 1017871 1018251 D Psort location: cytoplasmic, score: 23; hypothetical protein 1017871..1018251 Cronobacter sakazakii ATCC BAA-894 5548093 YP_001437161.1 CDS ESA_01057 NC_009778.1 1018255 1019844 R KEGG: pen:PSEEN3568 5.0e-153 ABC transporter, ATP-binding protein; COG: COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1018255..1019844) Cronobacter sakazakii ATCC BAA-894 5548095 YP_001437162.1 CDS ESA_01058 NC_009778.1 1019846 1020871 R COG: COG4239 ABC-type uncharacterized transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1019846..1020871) Cronobacter sakazakii ATCC BAA-894 5548455 YP_001437163.1 CDS ESA_01059 NC_009778.1 1020868 1021965 R KEGG: syf:Synpcc7942_2454 1.0e-35 adenine phosphoribosyltransferase K00759; COG: COG4174 ABC-type uncharacterized transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1020868..1021965) Cronobacter sakazakii ATCC BAA-894 5548258 YP_001437164.1 CDS ESA_01060 NC_009778.1 1021974 1023779 R COG: COG4166 ABC-type oligopeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1021974..1023779) Cronobacter sakazakii ATCC BAA-894 5548458 YP_001437165.1 CDS ESA_01061 NC_009778.1 1023875 1025437 R KEGG: vfi:VF0494 1.3e-37 sensory transduction protein kinase; COG: COG2200 FOG: EAL domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1023875..1025437) Cronobacter sakazakii ATCC BAA-894 5548228 YP_001437166.1 CDS spr NC_009778.1 1025607 1026176 R by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein complement(1025607..1026176) Cronobacter sakazakii ATCC BAA-894 5548301 YP_001437167.1 CDS ESA_01063 NC_009778.1 1026603 1027310 R KEGG: eci:UTI89_C2451 2.8e-79 hypothetical protein K01094; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1026603..1027310) Cronobacter sakazakii ATCC BAA-894 5548346 YP_001437168.1 CDS ESA_01065 NC_009778.1 1027341 1028327 R KEGG: reh:H16_A3373 1.9e-17 putative GTPase (G3E family); COG: COG0523 Putative GTPases (G3E family); Psort location: mitochondrial, score: 23; hypothetical protein complement(1027341..1028327) Cronobacter sakazakii ATCC BAA-894 5548146 YP_001437169.1 CDS ESA_01064 NC_009778.1 1028278 1028454 D Psort location: cytoplasmic, score: 23; hypothetical protein 1028278..1028454 Cronobacter sakazakii ATCC BAA-894 5551974 YP_001437170.1 CDS ESA_01067 NC_009778.1 1028458 1029720 R KEGG: ecp:ECP_2213 5.2e-174 hypothetical oxidoreductase YeiQ; COG: COG0246 Mannitol-1-phosphate/altronate dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1028458..1029720) Cronobacter sakazakii ATCC BAA-894 5548656 YP_001437171.1 CDS ESA_01066 NC_009778.1 1029694 1029954 D Psort location: cytoplasmic, score: 23; hypothetical protein 1029694..1029954 Cronobacter sakazakii ATCC BAA-894 5548714 YP_001437172.1 CDS ESA_01068 NC_009778.1 1030131 1031321 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 1030131..1031321 Cronobacter sakazakii ATCC BAA-894 5551948 YP_001437173.1 CDS ESA_01069 NC_009778.1 1031386 1031958 R Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P complement(1031386..1031958) Cronobacter sakazakii ATCC BAA-894 5551906 YP_001437174.1 CDS ESA_01070 NC_009778.1 1032150 1032434 D Psort location: cytoplasmic, score: 23; hypothetical protein 1032150..1032434 Cronobacter sakazakii ATCC BAA-894 5548691 YP_001437175.1 CDS ESA_01071 NC_009778.1 1032344 1032445 D Psort location: cytoplasmic, score: 23; hypothetical protein 1032344..1032445 Cronobacter sakazakii ATCC BAA-894 5548223 YP_001437176.1 CDS ESA_01072 NC_009778.1 1032531 1032719 D COG: COG0727 Predicted Fe-S-cluster oxidoreductase; Psort location: nuclear, score: 23; hypothetical protein 1032531..1032719 Cronobacter sakazakii ATCC BAA-894 5548111 YP_001437177.1 CDS ESA_01073 NC_009778.1 1032716 1033897 R COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(1032716..1033897) Cronobacter sakazakii ATCC BAA-894 5548423 YP_001437178.1 CDS ESA_01074 NC_009778.1 1034267 1035400 D phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 1034267..1035400 Cronobacter sakazakii ATCC BAA-894 5550472 YP_001437179.1 CDS fruK NC_009778.1 1035397 1036335 D converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 1035397..1036335 Cronobacter sakazakii ATCC BAA-894 5548288 YP_001437180.1 CDS ESA_01076 NC_009778.1 1036352 1038049 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC 1036352..1038049 Cronobacter sakazakii ATCC BAA-894 5550502 YP_001437181.1 CDS ESA_01077 NC_009778.1 1038049 1039008 D KEGG: reu:Reut_B5035 2.3e-70 4-hydroxyphenylpyruvate dioxygenase K00457; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein 1038049..1039008 Cronobacter sakazakii ATCC BAA-894 5548347 YP_001437182.1 CDS ESA_01078 NC_009778.1 1039009 1039866 R Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV complement(1039009..1039866) Cronobacter sakazakii ATCC BAA-894 5548145 YP_001437183.1 CDS ESA_01080 NC_009778.1 1039941 1040951 R COG: COG2855 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(1039941..1040951) Cronobacter sakazakii ATCC BAA-894 5548201 YP_001437184.1 CDS ESA_01079 NC_009778.1 1040946 1041080 D Psort location: cytoplasmic, score: 23; hypothetical protein 1040946..1041080 Cronobacter sakazakii ATCC BAA-894 5548389 YP_001437185.1 CDS ESA_01081 NC_009778.1 1041108 1041974 D KEGG: shn:Shewana3_3435 1.9e-08 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; putative DNA-binding transcriptional regulator 1041108..1041974 Cronobacter sakazakii ATCC BAA-894 5548259 YP_001437186.1 CDS ESA_01082 NC_009778.1 1042140 1043630 D KEGG: eci:UTI89_C0120 3.7e-70 aroP; aromatic amino acid transport protein AroP K03293; COG: COG0833 Amino acid transporters; Psort location: plasma membrane, score: 23; lysine transporter 1042140..1043630 Cronobacter sakazakii ATCC BAA-894 5548293 YP_001437187.1 CDS ESA_01083 NC_009778.1 1043843 1044592 R KEGG: eco:b2154 6.0e-102 yeiG; putative esterase K03929; COG: COG0627 Predicted esterase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1043843..1044592) Cronobacter sakazakii ATCC BAA-894 5548432 YP_001437188.1 CDS ESA_01084 NC_009778.1 1044797 1045921 D KEGG: eci:UTI89_C5041 4.2e-30 yjiJ; hypothetical protein YjiJ K00403; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 1044797..1045921 Cronobacter sakazakii ATCC BAA-894 5548398 YP_001437189.1 CDS folE NC_009778.1 1045986 1046717 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1045986..1046717 Cronobacter sakazakii ATCC BAA-894 5548263 YP_001437190.1 CDS ESA_01086 NC_009778.1 1046726 1047883 D COG: COG2311 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1046726..1047883 Cronobacter sakazakii ATCC BAA-894 5552180 YP_001437191.1 CDS ESA_01087 NC_009778.1 1048039 1049064 D negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 1048039..1049064 Cronobacter sakazakii ATCC BAA-894 5548157 YP_001437192.1 CDS ESA_01088 NC_009778.1 1049348 1050346 D KEGG: msm:MSMEG_3095 2.4e-13 D-ribose-binding periplasmic protein; COG: COG1879 ABC-type sugar transport system, periplasmic component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1049348..1050346 Cronobacter sakazakii ATCC BAA-894 5548236 YP_001437193.1 CDS ESA_01089 NC_009778.1 1050428 1051948 D with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 1050428..1051948 Cronobacter sakazakii ATCC BAA-894 5548334 YP_001437194.1 CDS mglC NC_009778.1 1051964 1052974 D ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 1051964..1052974 Cronobacter sakazakii ATCC BAA-894 5548143 YP_001437195.1 CDS ESA_01091 NC_009778.1 1053690 1054403 R COG: COG2949 Uncharacterized membrane protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1053690..1054403) Cronobacter sakazakii ATCC BAA-894 5548118 YP_001437196.1 CDS ESA_01092 NC_009778.1 1054528 1055412 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(1054528..1055412) Cronobacter sakazakii ATCC BAA-894 5548445 YP_001437197.1 CDS ESA_01093 NC_009778.1 1055542 1056237 R KEGG: bcz:BCZK3376 3.7e-31 murein hydrolase export regulator K01238; COG: COG1346 Putative effector of murein hydrolase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1055542..1056237) Cronobacter sakazakii ATCC BAA-894 5548330 YP_001437198.1 CDS ESA_01094 NC_009778.1 1056234 1056668 R KEGG: btk:BT9727_3424 2.1e-12 murein hydrolase exporter K06518; COG: COG1380 Putative effector of murein hydrolase LrgA; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1056234..1056668) Cronobacter sakazakii ATCC BAA-894 5548410 YP_001437199.1 CDS ESA_01095 NC_009778.1 1056888 1057235 D COG: COG4683 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1056888..1057235 Cronobacter sakazakii ATCC BAA-894 5548250 YP_001437200.1 CDS ESA_01096 NC_009778.1 1057059 1057223 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1057059..1057223) Cronobacter sakazakii ATCC BAA-894 5548727 YP_001437201.1 CDS ESA_01097 NC_009778.1 1057236 1057535 D COG: NOG21794 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1057236..1057535 Cronobacter sakazakii ATCC BAA-894 5548277 YP_001437202.1 CDS ESA_01098 NC_009778.1 1057606 1058538 D KEGG: eca:ECA2799 9.3e-145 putative dihydrouridine synthase K05541; COG: COG0042 tRNA-dihydrouridine synthase; Psort location: cytoplasmic, score: 23; tRNA-dihydrouridine synthase C 1057606..1058538 Cronobacter sakazakii ATCC BAA-894 5548495 YP_001437203.1 CDS ESA_01099 NC_009778.1 1058541 1059464 R KEGG: shn:Shewana3_3435 1.8e-08 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1058541..1059464) Cronobacter sakazakii ATCC BAA-894 5548528 YP_001437204.1 CDS ESA_01100 NC_009778.1 1059537 1060496 D KEGG: cvi:CV0271 5.9e-79 mpd; methyl paraTHIon hydrolase; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1059537..1060496 Cronobacter sakazakii ATCC BAA-894 5548607 YP_001437205.1 CDS ESA_01101 NC_009778.1 1060789 1061562 D KEGG: ecs:ECs3024 2.9e-102 oxidoreductase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; acetoin dehydrogenase 1060789..1061562 Cronobacter sakazakii ATCC BAA-894 5548558 YP_001437206.1 CDS ESA_01102 NC_009778.1 1061559 1062125 R KEGG: bcl:ABC0731 3.2e-07 alkaline phosphatase K01077; COG: COG0586 Uncharacterized membrane-associated protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1061559..1062125) Cronobacter sakazakii ATCC BAA-894 5548173 YP_001437207.1 CDS ESA_01103 NC_009778.1 1062350 1062895 D COG: NOG06773 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1062350..1062895 Cronobacter sakazakii ATCC BAA-894 5548207 YP_001437208.1 CDS pbpG NC_009778.1 1063062 1063994 D specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 1063062..1063994 Cronobacter sakazakii ATCC BAA-894 5552496 YP_001437209.1 CDS ESA_01105 NC_009778.1 1063996 1064595 R KEGG: bur:Bcep18194_B1154 4.9e-52 GCN5-related N-acetyltransferase K03823; COG: COG1247 Sortase and related acyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1063996..1064595) Cronobacter sakazakii ATCC BAA-894 5548326 YP_001437210.1 CDS ESA_01106 NC_009778.1 1064643 1066436 R component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase complement(1064643..1066436) Cronobacter sakazakii ATCC BAA-894 5548499 YP_001437211.1 CDS ESA_01107 NC_009778.1 1066612 1068885 D KEGG: ecj:JW2120 0. bglX; beta-D-glucoside glucohydrolase, periplasmic K05349; COG: COG1472 Beta-glucosidase-related glycosidases; Psort location: cytoplasmic, score: 23; hypothetical protein 1066612..1068885 Cronobacter sakazakii ATCC BAA-894 5548358 YP_001437212.1 CDS ESA_01108 NC_009778.1 1069042 1069950 D KEGG: lwe:lwe1439 1.4e-22 glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; COG: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1069042..1069950 Cronobacter sakazakii ATCC BAA-894 5548579 YP_001437213.1 CDS ESA_01109 NC_009778.1 1070004 1071137 D KEGG: lwe:lwe1439 7.4e-33 glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; COG: COG1174 ABC-type proline/glycine betaine transport systems, permease component; Psort location: plasma membrane, score: 23; hypothetical protein 1070004..1071137 Cronobacter sakazakii ATCC BAA-894 5548530 YP_001437214.1 CDS ESA_01110 NC_009778.1 1071130 1072071 D KEGG: bur:Bcep18194_B0497 9.5e-72 ABC proline/glycine betaine transporter, ATPase subunit K05847; COG: COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein 1071130..1072071 Cronobacter sakazakii ATCC BAA-894 5552366 YP_001437215.1 CDS ESA_01111 NC_009778.1 1072064 1072795 D KEGG: lwe:lwe1439 5.7e-29 glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; COG: COG1174 ABC-type proline/glycine betaine transport systems, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1072064..1072795 Cronobacter sakazakii ATCC BAA-894 5548475 YP_001437216.1 CDS ESA_01113 NC_009778.1 1072773 1072883 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1072773..1072883) Cronobacter sakazakii ATCC BAA-894 5548465 YP_001437217.1 CDS ESA_01112 NC_009778.1 1072785 1072910 D Psort location: cytoplasmic, score: 23; hypothetical protein 1072785..1072910 Cronobacter sakazakii ATCC BAA-894 5548128 YP_001437218.1 CDS ESA_01114 NC_009778.1 1072943 1073686 R KEGG: eci:UTI89_C3737 9.4e-10 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1072943..1073686) Cronobacter sakazakii ATCC BAA-894 5548572 YP_001437219.1 CDS metG NC_009778.1 1073867 1075939 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1073867..1075939) Cronobacter sakazakii ATCC BAA-894 5548673 YP_001437220.1 CDS ESA_01116 NC_009778.1 1076055 1077329 R COG: COG1566 Multidrug resistance efflux pump; Psort location: golgi, score: 9; hypothetical protein complement(1076055..1077329) Cronobacter sakazakii ATCC BAA-894 5548509 YP_001437221.1 CDS ESA_01117 NC_009778.1 1077322 1078893 R COG: NOG14231 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1077322..1078893) Cronobacter sakazakii ATCC BAA-894 5548485 YP_001437222.1 CDS ESA_01118 NC_009778.1 1078796 1080073 R KEGG: rru:Rru_A3236 6.4e-34 hypothetical protein K06020; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1078796..1080073) Cronobacter sakazakii ATCC BAA-894 5552313 YP_001437223.1 CDS ESA_01119 NC_009778.1 1080033 1080512 R KEGG: reh:H16_A1174 2.2e-33 ABC-type transporter, ATPase component: LPT family; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: nuclear, score: 23; hypothetical protein complement(1080033..1080512) Cronobacter sakazakii ATCC BAA-894 5548510 YP_001437224.1 CDS ESA_01120 NC_009778.1 1080774 1081628 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1080774..1081628) Cronobacter sakazakii ATCC BAA-894 5548599 YP_001437225.1 CDS ESA_01121 NC_009778.1 1082428 1082766 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1082428..1082766 Cronobacter sakazakii ATCC BAA-894 5548133 YP_001437226.1 CDS ESA_01122 NC_009778.1 1082903 1084012 D KEGG: eci:UTI89_C2387 7.3e-184 mrp; putative ATPase K03593; COG: COG0489 ATPases involved in chromosome partitioning; Psort location: cytoplasmic, score: 23; putative ATPase 1082903..1084012 Cronobacter sakazakii ATCC BAA-894 5548504 YP_001437227.1 CDS ESA_01123 NC_009778.1 1084069 1084509 R KEGG: aha:AHA_3047 1.5e-11 acetyltransferase YjaB K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1084069..1084509) Cronobacter sakazakii ATCC BAA-894 5548480 YP_001437228.1 CDS ESA_01124 NC_009778.1 1084602 1086293 D KEGG: stm:STM2159 3.8e-251 yehU; paral putative sensor/kinase in regulatory system K07704; COG: COG3275 Putative regulator of cell autolysis; Psort location: plasma membrane, score: 23; hypothetical protein 1084602..1086293 Cronobacter sakazakii ATCC BAA-894 5548568 YP_001437229.1 CDS ESA_01125 NC_009778.1 1086290 1087015 D unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT 1086290..1087015 Cronobacter sakazakii ATCC BAA-894 5548560 YP_001437230.1 CDS ESA_01126 NC_009778.1 1087126 1088670 D KEGG: abo:ABO_1307 5.7e-06 sensor histidine kinase/respose regulator; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1087126..1088670 Cronobacter sakazakii ATCC BAA-894 5548407 YP_001437231.1 CDS ESA_01127 NC_009778.1 1088888 1089865 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1088888..1089865 Cronobacter sakazakii ATCC BAA-894 5548588 YP_001437232.1 CDS ESA_01128 NC_009778.1 1089873 1090478 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1089873..1090478 Cronobacter sakazakii ATCC BAA-894 5548623 YP_001437233.1 CDS ESA_01129 NC_009778.1 1090554 1092278 R KEGG: bur:Bcep18194_C7259 2.2e-152 ABC transporter, duplicated ATPase domains; COG: COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1090554..1092278) Cronobacter sakazakii ATCC BAA-894 5548177 YP_001437234.1 CDS ESA_01130 NC_009778.1 1092638 1093036 R COG: COG5455 Predicted integral membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1092638..1093036) Cronobacter sakazakii ATCC BAA-894 5548494 YP_001437235.1 CDS ESA_01131 NC_009778.1 1093154 1093513 D Psort location: cytoplasmic, score: 23; hypothetical protein 1093154..1093513 Cronobacter sakazakii ATCC BAA-894 5548477 YP_001437236.1 CDS ESA_01132 NC_009778.1 1093629 1094201 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1093629..1094201 Cronobacter sakazakii ATCC BAA-894 5551480 YP_001437237.1 CDS ESA_01133 NC_009778.1 1094642 1095439 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 1094642..1095439 Cronobacter sakazakii ATCC BAA-894 5551492 YP_001437238.1 CDS ESA_01134 NC_009778.1 1095426 1096226 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1095426..1096226 Cronobacter sakazakii ATCC BAA-894 5548429 YP_001437239.1 CDS ESA_01135 NC_009778.1 1096371 1097426 D catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 1096371..1097426 Cronobacter sakazakii ATCC BAA-894 5548471 YP_001437240.1 CDS ESA_01136 NC_009778.1 1098154 1099053 R cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase complement(1098154..1099053) Cronobacter sakazakii ATCC BAA-894 5548414 YP_001437241.1 CDS ESA_01138 NC_009778.1 1099304 1100665 R KEGG: eci:UTI89_C2360 4.8e-235 yegQ; hypothetical protein K08303; COG: COG0826 Collagenase and related proteases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1099304..1100665) Cronobacter sakazakii ATCC BAA-894 5548540 YP_001437242.1 CDS ESA_01139 NC_009778.1 1100892 1101614 R response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR complement(1100892..1101614) Cronobacter sakazakii ATCC BAA-894 5548584 YP_001437243.1 CDS ESA_01140 NC_009778.1 1101611 1103035 R KEGG: ssn:SSO_2130 7.0e-195 baeS; sensor protein (for BaeR) K07642; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; signal transduction histidine-protein kinase BaeS complement(1101611..1103035) Cronobacter sakazakii ATCC BAA-894 5548672 YP_001437244.1 CDS ESA_01141 NC_009778.1 1103032 1104447 R KEGG: sgl:SG1466 6.1e-08 dethiobiotinsynthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; multidrug efflux system protein MdtE complement(1103032..1104447) Cronobacter sakazakii ATCC BAA-894 5548640 YP_001437245.1 CDS ESA_01142 NC_009778.1 1104451 1107540 R Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC complement(1104451..1107540) Cronobacter sakazakii ATCC BAA-894 5552416 YP_001437246.1 CDS ESA_01143 NC_009778.1 1107541 1110663 R Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB complement(1107541..1110663) Cronobacter sakazakii ATCC BAA-894 5548692 YP_001437247.1 CDS ESA_01144 NC_009778.1 1110663 1111910 R Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA complement(1110663..1111910) Cronobacter sakazakii ATCC BAA-894 5548789 YP_001437248.1 CDS ESA_01145 NC_009778.1 1112135 1112284 D Psort location: cytoplasmic, score: 23; hypothetical protein 1112135..1112284 Cronobacter sakazakii ATCC BAA-894 5548769 YP_001437249.1 CDS ESA_01146 NC_009778.1 1112281 1112502 D COG: COG4683 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1112281..1112502 Cronobacter sakazakii ATCC BAA-894 5548759 YP_001437250.1 CDS ESA_01147 NC_009778.1 1112465 1112785 D KEGG: afu:AF2118 0.0061 guaB-2; IMP dehydrogenase K00088; COG: NOG21794 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1112465..1112785 Cronobacter sakazakii ATCC BAA-894 5548681 YP_001437251.1 CDS ESA_01148 NC_009778.1 1112795 1114147 R KEGG: mbo:Mb0358 3.4e-09 dnaK; probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kda protein) (HSP70) K04043; COG: COG0443 Molecular chaperone; Psort location: cytoplasmic, score: 23; putative chaperone complement(1112795..1114147) Cronobacter sakazakii ATCC BAA-894 5548585 YP_001437252.1 CDS ESA_01149 NC_009778.1 1114283 1115131 D inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase II 1114283..1115131 Cronobacter sakazakii ATCC BAA-894 5548261 YP_001437253.1 CDS ESA_01150 NC_009778.1 1115121 1118510 R contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein complement(1115121..1118510) Cronobacter sakazakii ATCC BAA-894 5548610 YP_001437254.1 CDS ESA_01151 NC_009778.1 1118556 1118723 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1118556..1118723) Cronobacter sakazakii ATCC BAA-894 5548779 YP_001437255.1 CDS ESA_01152 NC_009778.1 1118811 1119452 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1118811..1119452 Cronobacter sakazakii ATCC BAA-894 5550459 YP_001437256.1 CDS dcd NC_009778.1 1119536 1120117 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1119536..1120117 Cronobacter sakazakii ATCC BAA-894 5548614 YP_001437257.1 CDS ESA_01154 NC_009778.1 1120148 1121989 D YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein 1120148..1121989 Cronobacter sakazakii ATCC BAA-894 5548604 YP_001437258.1 CDS ESA_01155 NC_009778.1 1122049 1123638 R KEGG: eci:UTI89_C0656 1.4e-25 ybeX; putative transport protein K06189; COG: COG1253 Hemolysins and related proteins containing CBS domains; Psort location: plasma membrane, score: 23; hypothetical protein complement(1122049..1123638) Cronobacter sakazakii ATCC BAA-894 5548573 YP_001437259.1 CDS ESA_01156 NC_009778.1 1124371 1125510 D COG: COG1596 Periplasmic protein involved in polysaccharide export; Psort location: mitochondrial, score: 23; hypothetical protein 1124371..1125510 Cronobacter sakazakii ATCC BAA-894 5548554 YP_001437260.1 CDS ESA_01157 NC_009778.1 1125510 1125959 D Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 1125510..1125959 Cronobacter sakazakii ATCC BAA-894 5551917 YP_001437261.1 CDS ESA_01158 NC_009778.1 1125962 1128124 D Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 1125962..1128124 Cronobacter sakazakii ATCC BAA-894 5548542 YP_001437262.1 CDS ESA_01159 NC_009778.1 1128314 1129159 D KEGG: eci:UTI89_C2333 2.7e-129 wcaA; putative colanic acid biosynthesis glycosyltransferase WcaA; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: mitochondrial, score: 23; putative glycosyl transferase 1128314..1129159 Cronobacter sakazakii ATCC BAA-894 5548518 YP_001437263.1 CDS ESA_01160 NC_009778.1 1129159 1129650 D acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB 1129159..1129650 Cronobacter sakazakii ATCC BAA-894 5548450 YP_001437264.1 CDS ESA_01161 NC_009778.1 1129647 1130864 D KEGG: eci:UTI89_C2331 3.0e-178 wcaC; putative glycosyltransferase K00754; COG: COG0438 Glycosyltransferase; Psort location: cytoplasmic, score: 23; putative glycosyl transferase 1129647..1130864 Cronobacter sakazakii ATCC BAA-894 5548590 YP_001437265.1 CDS wcaD NC_009778.1 1130839 1132059 D essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 1130839..1132059 Cronobacter sakazakii ATCC BAA-894 5548567 YP_001437266.1 CDS ESA_01163 NC_009778.1 1132074 1132826 D KEGG: eci:UTI89_C2329 7.1e-99 wcaE; putative colanic acid biosynthesis glycosyl transferase; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: cytoplasmic, score: 23; putative glycosyl transferase 1132074..1132826 Cronobacter sakazakii ATCC BAA-894 5548597 YP_001437267.1 CDS ESA_01164 NC_009778.1 1132849 1133397 D acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF 1132849..1133397 Cronobacter sakazakii ATCC BAA-894 5548587 YP_001437268.1 CDS ESA_01165 NC_009778.1 1133531 1134652 D KEGG: ecc:c2579 1.6e-195 gmd; GDP-mannose 4,6-dehydratase K01711; COG: COG1089 GDP-D-mannose dehydratase; Psort location: cytoplasmic, score: 23; hypothetical protein 1133531..1134652 Cronobacter sakazakii ATCC BAA-894 5548132 YP_001437269.1 CDS ESA_01166 NC_009778.1 1134655 1135620 D KEGG: ecc:c2578 2.0e-156 wcaG; GDP-fucose synthetase K02377; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein 1134655..1135620 Cronobacter sakazakii ATCC BAA-894 5550815 YP_001437270.1 CDS ESA_01167 NC_009778.1 1135623 1136102 D KEGG: sfl:SF2114 6.6e-64 wcaH; GDP-mannose mannosyl hydrolase K03207; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 1135623..1136102 Cronobacter sakazakii ATCC BAA-894 5548625 YP_001437271.1 CDS ESA_01168 NC_009778.1 1136099 1137322 D KEGG: eci:UTI89_C2324 1.2e-183 wcaI; putative colanic biosynthesis glycosyl transferase K03208; COG: COG0438 Glycosyltransferase; Psort location: cytoplasmic, score: 23; putative glycosyl transferase 1136099..1137322 Cronobacter sakazakii ATCC BAA-894 5548513 YP_001437272.1 CDS ESA_01169 NC_009778.1 1137326 1138768 D KEGG: ecc:c2575 7.8e-235 cpsB; mannose-1-phosphate guanylyltransferase K00971; COG: COG0662 Mannose-6-phosphate isomerase; Psort location: cytoplasmic, score: 23; hypothetical protein 1137326..1138768 Cronobacter sakazakii ATCC BAA-894 5548908 YP_001437273.1 CDS ESA_01170 NC_009778.1 1138824 1140194 D KEGG: ecc:c2573 9.4e-223 cpsG; phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: cytoplasmic, score: 23; hypothetical protein 1138824..1140194 Cronobacter sakazakii ATCC BAA-894 5548968 YP_001437274.1 CDS ESA_01171 NC_009778.1 1140309 1141703 D WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase 1140309..1141703 Cronobacter sakazakii ATCC BAA-894 5550856 YP_001437275.1 CDS ESA_01172 NC_009778.1 1141716 1143194 D COG: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Psort location: plasma membrane, score: 23; colanic acid exporter 1141716..1143194 Cronobacter sakazakii ATCC BAA-894 5550844 YP_001437276.1 CDS ESA_01173 NC_009778.1 1143274 1144554 D KEGG: sbo:SBO_0872 6.7e-190 wcaK; putative galactokinase K00849; COG: COG2327 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; putative pyruvyl transferase 1143274..1144554 Cronobacter sakazakii ATCC BAA-894 5548662 YP_001437277.1 CDS ESA_01174 NC_009778.1 1144551 1145771 D KEGG: eco:b2044 4.2e-165 wcaL, yefL; putative colanic acid biosynthesis glycosyl transferase; COG: COG0438 Glycosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 1144551..1145771 Cronobacter sakazakii ATCC BAA-894 5548707 YP_001437278.1 CDS wcaM NC_009778.1 1145783 1147198 D WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein 1145783..1147198 Cronobacter sakazakii ATCC BAA-894 5552427 YP_001437279.1 CDS ESA_01176 NC_009778.1 1147414 1148409 D KEGG: sat:SYN_02668 7.5e-24 UDP-glucose 4-epimerase K01784; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein 1147414..1148409 Cronobacter sakazakii ATCC BAA-894 5550568 YP_001437280.1 CDS ESA_01177 NC_009778.1 1148639 1149529 D together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 1148639..1149529 Cronobacter sakazakii ATCC BAA-894 5548685 YP_001437281.1 CDS ESA_01178 NC_009778.1 1149921 1151000 D NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose 4,6 dehydratase 1149921..1151000 Cronobacter sakazakii ATCC BAA-894 5548752 YP_001437282.1 CDS ESA_01179 NC_009778.1 1150997 1151869 D KEGG: nme:NMB0062 6.2e-116 glucose-1-phosphate thymidylyltransferase K00973; COG: COG1209 dTDP-glucose pyrophosphorylase; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1150997..1151869 Cronobacter sakazakii ATCC BAA-894 5548669 YP_001437283.1 CDS ESA_01180 NC_009778.1 1152265 1152717 D KEGG: btl:BALH_2628 7.5e-08 acetyltransferase, GNAT family K00680; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 1152265..1152717 Cronobacter sakazakii ATCC BAA-894 5548694 YP_001437284.1 CDS ESA_01181 NC_009778.1 1152718 1153653 D Psort location: cytoplasmic, score: 23; hypothetical protein 1152718..1153653 Cronobacter sakazakii ATCC BAA-894 5548699 YP_001437285.1 CDS ESA_01182 NC_009778.1 1153650 1154753 D KEGG: ava:Ava_0899 9.8e-54 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme K00811; COG: COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Psort location: cytoplasmic, score: 23; hypothetical protein 1153650..1154753 Cronobacter sakazakii ATCC BAA-894 5548622 YP_001437286.1 CDS ESA_01183 NC_009778.1 1154750 1156012 D COG: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1154750..1156012 Cronobacter sakazakii ATCC BAA-894 5548648 YP_001437287.1 CDS ESA_01184 NC_009778.1 1156012 1156956 D KEGG: mma:MM1141 1.5e-14 glycosyltransferase K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: cytoplasmic, score: 23; hypothetical protein 1156012..1156956 Cronobacter sakazakii ATCC BAA-894 5548541 YP_001437288.1 CDS ESA_01185 NC_009778.1 1157073 1158275 D Psort location: plasma membrane, score: 23; hypothetical protein 1157073..1158275 Cronobacter sakazakii ATCC BAA-894 5548667 YP_001437289.1 CDS ESA_01186 NC_009778.1 1158566 1158694 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1158566..1158694 Cronobacter sakazakii ATCC BAA-894 5548698 YP_001437290.1 CDS ESA_01187 NC_009778.1 1158841 1159140 D Psort location: nuclear, score: 23; hypothetical protein 1158841..1159140 Cronobacter sakazakii ATCC BAA-894 5552034 YP_001437291.1 CDS ESA_01188 NC_009778.1 1159130 1159894 D KEGG: aha:AHA_2883 1.1e-54 glycosyl transferase, group 2 family protein K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: nuclear, score: 23; hypothetical protein 1159130..1159894 Cronobacter sakazakii ATCC BAA-894 5548675 YP_001437292.1 CDS ESA_01189 NC_009778.1 1160108 1161514 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1160108..1161514 Cronobacter sakazakii ATCC BAA-894 5548761 YP_001437293.1 CDS ESA_01190 NC_009778.1 1161724 1162734 D KEGG: pfo:Pfl_3844 0.00010 lipopolysaccharide biosynthesis K00903; COG: COG3765 Chain length determinant protein; Psort location: plasma membrane, score: 23; hypothetical protein 1161724..1162734 Cronobacter sakazakii ATCC BAA-894 5548654 YP_001437294.1 CDS ESA_01191 NC_009778.1 1162796 1163407 R KEGG: sdy:SDY_2215 8.3e-89 hisI; phosphoribosyl-amp cyclohydrolase K01496:K01523; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1162796..1163407) Cronobacter sakazakii ATCC BAA-894 5548666 YP_001437295.1 CDS ESA_01192 NC_009778.1 1163401 1164177 R catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF complement(1163401..1164177) Cronobacter sakazakii ATCC BAA-894 5548690 YP_001437296.1 CDS ESA_01193 NC_009778.1 1164159 1164896 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase complement(1164159..1164896) Cronobacter sakazakii ATCC BAA-894 5548653 YP_001437297.1 CDS hisH NC_009778.1 1164897 1165487 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(1164897..1165487) Cronobacter sakazakii ATCC BAA-894 5548719 YP_001437298.1 CDS ESA_01195 NC_009778.1 1165487 1166554 R catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase complement(1165487..1166554) Cronobacter sakazakii ATCC BAA-894 5548713 YP_001437299.1 CDS ESA_01196 NC_009778.1 1166551 1167633 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(1166551..1167633) Cronobacter sakazakii ATCC BAA-894 5548535 YP_001437300.1 CDS hisD NC_009778.1 1167630 1168934 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(1167630..1168934) Cronobacter sakazakii ATCC BAA-894 5548621 YP_001437301.1 CDS ESA_01198 NC_009778.1 1168940 1169410 R KEGG: eca:ECA2582 5.7e-74 hisG; ATP phosphoribosyltransferase K00765; COG: COG0040 ATP phosphoribosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1168940..1169410) Cronobacter sakazakii ATCC BAA-894 5552138 YP_001437302.1 CDS ESA_01199 NC_009778.1 1169417 1169791 D Psort location: cytoplasmic, score: 23; hypothetical protein 1169417..1169791 Cronobacter sakazakii ATCC BAA-894 5548726 YP_001437303.1 CDS ESA_01200 NC_009778.1 1169994 1170179 D Psort location: cytoplasmic, score: 23; hypothetical protein 1169994..1170179 Cronobacter sakazakii ATCC BAA-894 5548658 YP_001437304.1 CDS ESA_01201 NC_009778.1 1170216 1171040 D KEGG: eba:ebA1635 2.8e-08 galE1; hypothetical protein K01784; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1170216..1171040 Cronobacter sakazakii ATCC BAA-894 5548457 YP_001437305.1 CDS ESA_01202 NC_009778.1 1171024 1171803 R KEGG: cvi:CV2023 7.3e-42 probable amidophosphoribosyltransferase K00764; COG: COG2071 Predicted glutamine amidotransferases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1171024..1171803) Cronobacter sakazakii ATCC BAA-894 5548926 YP_001437306.1 CDS ESA_01204 NC_009778.1 1171754 1172080 R Psort location: nuclear, score: 23; hypothetical protein complement(1171754..1172080) Cronobacter sakazakii ATCC BAA-894 5548705 YP_001437307.1 CDS ESA_01203 NC_009778.1 1172010 1173365 D KEGG: aha:AHA_3002 6.7e-158 gabT; 4-aminobutyrate transaminase K00823; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: extracellular, including cell wall, score: 23; hypothetical protein 1172010..1173365 Cronobacter sakazakii ATCC BAA-894 5548740 YP_001437308.1 CDS ESA_01205 NC_009778.1 1173626 1174915 D KEGG: eci:UTI89_C0120 1.3e-12 aroP; aromatic amino acid transport protein AroP K03293; COG: COG0531 Amino acid transporters; Psort location: plasma membrane, score: 23; hypothetical protein 1173626..1174915 Cronobacter sakazakii ATCC BAA-894 5548624 YP_001437309.1 CDS sbcB NC_009778.1 1175212 1176687 R Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I complement(1175212..1176687) Cronobacter sakazakii ATCC BAA-894 5548702 YP_001437310.1 CDS ESA_01207 NC_009778.1 1176717 1177868 R KEGG: mtu:Rv0517 1.0e-13 possible membrane acyltransferase K00680; COG: COG1835 Predicted acyltransferases; Psort location: plasma membrane, score: 23; hypothetical protein complement(1176717..1177868) Cronobacter sakazakii ATCC BAA-894 5548643 YP_001437311.1 CDS dacD NC_009778.1 1178106 1179278 D removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1178106..1179278 Cronobacter sakazakii ATCC BAA-894 5548728 YP_001437312.1 CDS ESA_01209 NC_009778.1 1179318 1179839 D COG: COG3449 DNA gyrase inhibitor; Psort location: cytoplasmic, score: 23; DNA gyrase inhibitor 1179318..1179839 Cronobacter sakazakii ATCC BAA-894 5548768 YP_001437313.1 CDS ESA_01211 NC_009778.1 1179962 1180105 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1179962..1180105) Cronobacter sakazakii ATCC BAA-894 5548741 YP_001437314.1 CDS ESA_01210 NC_009778.1 1180100 1181098 D COG: COG1289 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1180100..1181098 Cronobacter sakazakii ATCC BAA-894 5552054 YP_001437315.1 CDS ESA_01212 NC_009778.1 1181267 1181605 D KEGG: bba:Bd3749 0.0024 lon; ATP-dependent protease La K01338; COG: COG2926 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 1181267..1181605 Cronobacter sakazakii ATCC BAA-894 5548628 YP_001437316.1 CDS ESA_01214 NC_009778.1 1182057 1183457 D KEGG: rxy:Rxyl_3145 0.0054 NADH dehydrogenase (quinone) K05903; COG: COG0534 Na+-driven multidrug efflux pump; Psort location: plasma membrane, score: 23; hypothetical protein 1182057..1183457 Cronobacter sakazakii ATCC BAA-894 5548633 YP_001437317.1 CDS ESA_01215 NC_009778.1 1183849 1186371 D COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1183849..1186371 Cronobacter sakazakii ATCC BAA-894 5552375 YP_001437318.1 CDS ESA_01216 NC_009778.1 1186371 1187672 D COG: NOG18468 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1186371..1187672 Cronobacter sakazakii ATCC BAA-894 5552248 YP_001437319.1 CDS ESA_01217 NC_009778.1 1187684 1188904 D COG: NOG18467 non supervised orthologous group; Psort location: cytoskeletal, score: 9; hypothetical protein 1187684..1188904 Cronobacter sakazakii ATCC BAA-894 5548754 YP_001437320.1 CDS ESA_01218 NC_009778.1 1189002 1190015 D COG: NOG18467 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1189002..1190015 Cronobacter sakazakii ATCC BAA-894 5548748 YP_001437321.1 CDS ESA_01220 NC_009778.1 1190332 1191786 R Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase complement(1190332..1191786) Cronobacter sakazakii ATCC BAA-894 5548929 YP_001437322.1 CDS ESA_01221 NC_009778.1 1192114 1193325 D KEGG: shn:Shewana3_3829 1.5e-14 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: cytoplasmic, score: 23; hypothetical protein 1192114..1193325 Cronobacter sakazakii ATCC BAA-894 5548802 YP_001437323.1 CDS ESA_01222 NC_009778.1 1193516 1194592 D KEGG: ret:RHE_CH02675 6.9e-156 probable alkanal monooxygenase (bacterial liciferase alpha chain) like protein K00494; COG: COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; Psort location: cytoplasmic, score: 23; hypothetical protein 1193516..1194592 Cronobacter sakazakii ATCC BAA-894 5548770 YP_001437324.1 CDS ESA_01224 NC_009778.1 1195036 1195953 D Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 1195036..1195953 Cronobacter sakazakii ATCC BAA-894 5548995 YP_001437325.1 CDS cbl NC_009778.1 1196055 1197008 D LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 1196055..1197008 Cronobacter sakazakii ATCC BAA-894 5548907 YP_001437326.1 CDS ESA_01226 NC_009778.1 1197051 1198385 R KEGG: cal:orf19.5753 0.0050 STL1; sugar transporter K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; shikimate transporter complement(1197051..1198385) Cronobacter sakazakii ATCC BAA-894 5548987 YP_001437327.1 CDS ESA_01228 NC_009778.1 1198814 1199611 R COG: COG3228 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1198814..1199611) Cronobacter sakazakii ATCC BAA-894 5548955 YP_001437328.1 CDS ESA_01230 NC_009778.1 1200163 1201740 D KEGG: ava:Ava_3170 2.4e-34 putative diguanylate cyclase (GGDEF domain) K02488; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1200163..1201740 Cronobacter sakazakii ATCC BAA-894 5548903 YP_001437329.1 CDS ESA_01231 NC_009778.1 1201747 1202649 R KEGG: shn:Shewana3_3435 4.2e-07 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1201747..1202649) Cronobacter sakazakii ATCC BAA-894 5548921 YP_001437330.1 CDS ESA_01232 NC_009778.1 1202770 1203618 D KEGG: ret:RHE_PF00538 2.2e-24 hypothetical protein K01423; COG: COG0693 Putative intracellular protease/amidase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1202770..1203618 Cronobacter sakazakii ATCC BAA-894 5548979 YP_001437331.1 CDS ESA_01233 NC_009778.1 1203648 1204442 D KEGG: chu:CHU_1425 3.8e-68 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 1203648..1204442 Cronobacter sakazakii ATCC BAA-894 5548997 YP_001437332.1 CDS ESA_01234 NC_009778.1 1204537 1204776 R COG: NOG15335 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1204537..1204776) Cronobacter sakazakii ATCC BAA-894 5548888 YP_001437333.1 CDS ESA_01235 NC_009778.1 1204930 1206120 R COG: COG3203 Outer membrane protein (porin); Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1204930..1206120) Cronobacter sakazakii ATCC BAA-894 5548885 YP_001437334.1 CDS ESA_01236 NC_009778.1 1206699 1207397 D COG: COG1418 Predicted HD superfamily hydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein 1206699..1207397 Cronobacter sakazakii ATCC BAA-894 5548866 YP_001437335.1 CDS ESA_01237 NC_009778.1 1207446 1208891 D KEGG: stm:STM1992 5.1e-192 dcm; DNA cytosine methylase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: cytoplasmic, score: 23; DNA cytosine methylase 1207446..1208891 Cronobacter sakazakii ATCC BAA-894 5548848 YP_001437336.1 CDS ESA_01238 NC_009778.1 1208875 1209372 D KEGG: eci:UTI89_C2161 2.7e-67 vsr; DNA mismatch endonuclease, patch repair protein K07458; COG: COG3727 DNA G:T-mismatch repair endonuclease; Psort location: cytoplasmic, score: 23; hypothetical protein 1208875..1209372 Cronobacter sakazakii ATCC BAA-894 5548834 YP_001437337.1 CDS ESA_01239 NC_009778.1 1209376 1210287 R KEGG: pae:PA1977 0.0056 sensor protein GLPS; COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(1209376..1210287) Cronobacter sakazakii ATCC BAA-894 5548838 YP_001437338.1 CDS ESA_01240 NC_009778.1 1210466 1211380 D KEGG: sru:SRU_1714 0.0086 cdsA; phosphatidate cytidylyltransferase K00981; COG: COG2354 Uncharacterized protein conserved in bacteria; Psort location: plasma membrane, score: 23; hypothetical protein 1210466..1211380 Cronobacter sakazakii ATCC BAA-894 5548837 YP_001437339.1 CDS ESA_01241 NC_009778.1 1211470 1211652 D COG: COG5475 Uncharacterized small protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1211470..1211652 Cronobacter sakazakii ATCC BAA-894 5548820 YP_001437340.1 CDS ESA_01242 NC_009778.1 1211649 1211852 D Psort location: cytoplasmic, score: 23; hypothetical protein 1211649..1211852 Cronobacter sakazakii ATCC BAA-894 5548839 YP_001437341.1 CDS ESA_01243 NC_009778.1 1211854 1213524 D KEGG: aha:AHA_1274 3.4e-24 response regulator PleD (stalked cell differentiation-controllingprotein) K05345; COG: COG2199 FOG: GGDEF domain; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1211854..1213524 Cronobacter sakazakii ATCC BAA-894 5548855 YP_001437342.1 CDS ESA_01244 NC_009778.1 1213528 1214343 R catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase complement(1213528..1214343) Cronobacter sakazakii ATCC BAA-894 5548912 YP_001437343.1 CDS ESA_01246 NC_009778.1 1214645 1214884 R Psort location: nuclear, score: 23; hypothetical protein complement(1214645..1214884) Cronobacter sakazakii ATCC BAA-894 5548881 YP_001437344.1 CDS ESA_01245 NC_009778.1 1214648 1215169 D COG: NOG14105 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 1214648..1215169 Cronobacter sakazakii ATCC BAA-894 5552479 YP_001437345.1 CDS ESA_01247 NC_009778.1 1215338 1215961 R COG: COG2771 DNA-binding HTH domain-containing proteins; Psort location: nuclear, score: 23; hypothetical protein complement(1215338..1215961) Cronobacter sakazakii ATCC BAA-894 5548852 YP_001437346.1 CDS fliR NC_009778.1 1216310 1217098 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(1216310..1217098) Cronobacter sakazakii ATCC BAA-894 5550727 YP_001437347.1 CDS fliQ NC_009778.1 1217110 1217382 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(1217110..1217382) Cronobacter sakazakii ATCC BAA-894 5548311 YP_001437348.1 CDS fliP NC_009778.1 1217391 1218128 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(1217391..1218128) Cronobacter sakazakii ATCC BAA-894 5550836 YP_001437349.1 CDS ESA_01251 NC_009778.1 1218128 1218505 R with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO complement(1218128..1218505) Cronobacter sakazakii ATCC BAA-894 5548105 YP_001437350.1 CDS fliN NC_009778.1 1218506 1218970 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN complement(1218506..1218970) Cronobacter sakazakii ATCC BAA-894 5549152 YP_001437351.1 CDS fliM NC_009778.1 1218963 1219967 R with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM complement(1218963..1219967) Cronobacter sakazakii ATCC BAA-894 5549159 YP_001437352.1 CDS fliL NC_009778.1 1219972 1220445 R interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL complement(1219972..1220445) Cronobacter sakazakii ATCC BAA-894 5551112 YP_001437353.1 CDS ESA_01255 NC_009778.1 1220549 1221811 R KEGG: rno:79011 0.0015 Camkv; CaM kinase-like vesicle-associated K08812; COG: COG3144 Flagellar hook-length control protein; Psort location: nuclear, score: 23; flagellar hook-length control protein complement(1220549..1221811) Cronobacter sakazakii ATCC BAA-894 5551358 YP_001437354.1 CDS fliJ NC_009778.1 1221808 1222266 R rod/hook and filament chaperone; flagellar biosynthesis chaperone complement(1221808..1222266) Cronobacter sakazakii ATCC BAA-894 5551278 YP_001437355.1 CDS fliI NC_009778.1 1222273 1223643 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(1222273..1223643) Cronobacter sakazakii ATCC BAA-894 5551120 YP_001437356.1 CDS fliH NC_009778.1 1223643 1224347 R binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H complement(1223643..1224347) Cronobacter sakazakii ATCC BAA-894 5551127 YP_001437357.1 CDS fliG NC_009778.1 1224340 1225362 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G complement(1224340..1225362) Cronobacter sakazakii ATCC BAA-894 5548945 YP_001437358.1 CDS fliF NC_009778.1 1225359 1227056 R the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein complement(1225359..1227056) Cronobacter sakazakii ATCC BAA-894 5548994 YP_001437359.1 CDS ESA_01261 NC_009778.1 1227287 1227598 D COG: COG1677 Flagellar hook-basal body protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1227287..1227598 Cronobacter sakazakii ATCC BAA-894 5548873 YP_001437360.1 CDS ESA_01262 NC_009778.1 1227653 1227922 D KEGG: ecc:c1631 1.5e-11 umuD; umuD protein K03503; COG: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Psort location: cytoplasmic, score: 23; hypothetical protein 1227653..1227922 Cronobacter sakazakii ATCC BAA-894 5548958 YP_001437361.1 CDS ESA_01263 NC_009778.1 1227942 1229126 D KEGG: eci:UTI89_C1370 2.6e-156 umuC; UmuC protein K03502; COG: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Psort location: cytoplasmic, score: 23; hypothetical protein 1227942..1229126 Cronobacter sakazakii ATCC BAA-894 5548959 YP_001437362.1 CDS ESA_01264 NC_009778.1 1229554 1230819 D Psort location: cytoplasmic, score: 23; hypothetical protein 1229554..1230819 Cronobacter sakazakii ATCC BAA-894 5548940 YP_001437363.1 CDS ESA_01265 NC_009778.1 1230993 1231595 R COG: COG0582 Integrase; Psort location: mitochondrial, score: 23; hypothetical protein complement(1230993..1231595) Cronobacter sakazakii ATCC BAA-894 5548957 YP_001437364.1 CDS ESA_01267 NC_009778.1 1231772 1231927 R Psort location: nuclear, score: 23; hypothetical protein complement(1231772..1231927) Cronobacter sakazakii ATCC BAA-894 5548962 YP_001437365.1 CDS ESA_01266 NC_009778.1 1231852 1232493 D Psort location: extracellular, including cell wall, score: 23; hypothetical protein 1231852..1232493 Cronobacter sakazakii ATCC BAA-894 5548941 YP_001437366.1 CDS ESA_01268 NC_009778.1 1232368 1232484 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1232368..1232484) Cronobacter sakazakii ATCC BAA-894 5548854 YP_001437367.1 CDS ESA_01269 NC_009778.1 1232611 1234203 D COG: NOG22465 non supervised orthologous group; Psort location: vacuolar, score: 9; hypothetical protein 1232611..1234203 Cronobacter sakazakii ATCC BAA-894 5548942 YP_001437368.1 CDS ESA_01270 NC_009778.1 1234648 1235547 D Psort location: cytoplasmic, score: 23; hypothetical protein 1234648..1235547 Cronobacter sakazakii ATCC BAA-894 5548943 YP_001437369.1 CDS ESA_01271 NC_009778.1 1235752 1236156 R COG: COG4316 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1235752..1236156) Cronobacter sakazakii ATCC BAA-894 5548976 YP_001437370.1 CDS ESA_01272 NC_009778.1 1236323 1236595 D KEGG: eci:UTI89_C1370 2.2e-22 umuC; UmuC protein K03502; COG: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Psort location: cytoplasmic, score: 23; hypothetical protein 1236323..1236595 Cronobacter sakazakii ATCC BAA-894 5548919 YP_001437371.1 CDS ESA_01273 NC_009778.1 1236681 1237520 R COG: COG1396 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1236681..1237520) Cronobacter sakazakii ATCC BAA-894 5548936 YP_001437372.1 CDS ESA_01274 NC_009778.1 1237620 1238516 D KEGG: lpl:lp_3108 1.4e-38 oxidoreductase (putative); COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: mitochondrial, score: 23; hypothetical protein 1237620..1238516 Cronobacter sakazakii ATCC BAA-894 5548937 YP_001437373.1 CDS ESA_01275 NC_009778.1 1238988 1239569 D KEGG: eci:UTI89_C0735 0.0020 tolA; membrane spanning protein TolA K03646; COG: COG3652 Predicted outer membrane protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1238988..1239569 Cronobacter sakazakii ATCC BAA-894 5548869 YP_001437374.1 CDS ESA_01276 NC_009778.1 1239760 1240977 R KEGG: eci:UTI89_C5041 9.4e-07 yjiJ; hypothetical protein YjiJ K00403; COG: COG2814 Arabinose efflux permease; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1239760..1240977) Cronobacter sakazakii ATCC BAA-894 5548875 YP_001437375.1 CDS ESA_01277 NC_009778.1 1240974 1241171 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1240974..1241171) Cronobacter sakazakii ATCC BAA-894 5548928 YP_001437376.1 CDS ESA_01278 NC_009778.1 1241386 1242297 D KEGG: shn:Shewana3_3435 4.4e-07 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1241386..1242297 Cronobacter sakazakii ATCC BAA-894 5548970 YP_001437377.1 CDS ESA_01279 NC_009778.1 1242654 1243259 D KEGG: aci:ACIAD0539 4.6e-40 putative methyltransferase; COG: COG0500 SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 1242654..1243259 Cronobacter sakazakii ATCC BAA-894 5549012 YP_001437378.1 CDS ESA_01280 NC_009778.1 1243306 1243455 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1243306..1243455) Cronobacter sakazakii ATCC BAA-894 5549010 YP_001437379.1 CDS ESA_01281 NC_009778.1 1243452 1244135 R COG: COG2135 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1243452..1244135) Cronobacter sakazakii ATCC BAA-894 5548906 YP_001437380.1 CDS ESA_01282 NC_009778.1 1244214 1244447 R COG: COG0425 Predicted redox protein, regulator of disulfide bond formation; Psort location: nuclear, score: 23; hypothetical protein complement(1244214..1244447) Cronobacter sakazakii ATCC BAA-894 5549193 YP_001437381.1 CDS ESA_01283 NC_009778.1 1244444 1245661 R COG: COG2391 Predicted transporter component; Psort location: endoplasmic reticulum, score: 9; putative inner membrane protein complement(1244444..1245661) Cronobacter sakazakii ATCC BAA-894 5549201 YP_001437382.1 CDS ESA_01284 NC_009778.1 1245865 1246278 D COG: NOG09020 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1245865..1246278 Cronobacter sakazakii ATCC BAA-894 5549083 YP_001437383.1 CDS ESA_01285 NC_009778.1 1246632 1246994 R binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT complement(1246632..1246994) Cronobacter sakazakii ATCC BAA-894 5549094 YP_001437384.1 CDS fliS NC_009778.1 1246994 1247404 R flagellin specific chaperone; flagellar protein FliS complement(1246994..1247404) Cronobacter sakazakii ATCC BAA-894 5549165 YP_001437385.1 CDS ESA_01287 NC_009778.1 1247414 1248844 R KEGG: cal:orf19.7586 1.5e-07 CHT3; chitinase 3 precursor K01183; COG: COG1345 Flagellar capping protein; Psort location: nuclear, score: 23; hypothetical protein complement(1247414..1248844) Cronobacter sakazakii ATCC BAA-894 5549196 YP_001437386.1 CDS ESA_01288 NC_009778.1 1249280 1250116 D COG: COG1344 Flagellin and related hook-associated proteins; Psort location: nuclear, score: 23; hypothetical protein 1249280..1250116 Cronobacter sakazakii ATCC BAA-894 5549051 YP_001437387.1 CDS ESA_01289 NC_009778.1 1250329 1251816 D COG: COG0500 SAM-dependent methyltransferases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1250329..1251816 Cronobacter sakazakii ATCC BAA-894 5548918 YP_001437388.1 CDS ESA_01290 NC_009778.1 1251838 1255188 D KEGG: mmu:108155 8.3e-30 Ogt; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) K00754; COG: COG3914 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family; Psort location: cytoplasmic, score: 23; hypothetical protein 1251838..1255188 Cronobacter sakazakii ATCC BAA-894 5549106 YP_001437389.1 CDS ESA_01291 NC_009778.1 1255258 1256391 D KEGG: psp:PSPPH_3420 4.2e-133 aminotransferase, DegT/DnrJ/EryC1/StrS family K01726; COG: COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Psort location: cytoplasmic, score: 23; hypothetical protein 1255258..1256391 Cronobacter sakazakii ATCC BAA-894 5549075 YP_001437390.1 CDS ESA_01292 NC_009778.1 1256388 1257026 D KEGG: rso:RS02341 2.3e-22 RSp1007; putative acetyl transferase protein K00680; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: cytoplasmic, score: 23; hypothetical protein 1256388..1257026 Cronobacter sakazakii ATCC BAA-894 5549074 YP_001437391.1 CDS ESA_01293 NC_009778.1 1257058 1257303 D Psort location: cytoplasmic, score: 23; hypothetical protein 1257058..1257303 Cronobacter sakazakii ATCC BAA-894 5549081 YP_001437392.1 CDS ESA_01294 NC_009778.1 1257305 1258066 D KEGG: lic:LIC20064 1.5e-41 fabG; 3-oxoacyl-(acyl-carrier protein) reductase K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1257305..1258066 Cronobacter sakazakii ATCC BAA-894 5549028 YP_001437393.1 CDS ESA_01295 NC_009778.1 1258079 1258822 D KEGG: mxa:MXAN_4770 1.1e-38 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 1258079..1258822 Cronobacter sakazakii ATCC BAA-894 5549052 YP_001437394.1 CDS ESA_01296 NC_009778.1 1258819 1258965 D Psort location: cytoplasmic, score: 23; hypothetical protein 1258819..1258965 Cronobacter sakazakii ATCC BAA-894 5549007 YP_001437395.1 CDS ESA_01297 NC_009778.1 1258962 1260377 D KEGG: gka:GK0668 2.6e-32 long-chain fatty-acid-CoA ligase K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: cytoplasmic, score: 23; hypothetical protein 1258962..1260377 Cronobacter sakazakii ATCC BAA-894 5549064 YP_001437396.1 CDS ESA_01298 NC_009778.1 1260370 1261452 D KEGG: cvi:CV4318 3.6e-19 luxE; long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase; COG: NOG06256 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1260370..1261452 Cronobacter sakazakii ATCC BAA-894 5549215 YP_001437397.1 CDS ESA_01299 NC_009778.1 1261436 1262638 D KEGG: vfi:VFA0923 1.3e-05 LuxC, acyl-CoA reductase; COG: NOG18388 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1261436..1262638 Cronobacter sakazakii ATCC BAA-894 5549192 YP_001437398.1 CDS fliA NC_009778.1 1262801 1263490 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1262801..1263490 Cronobacter sakazakii ATCC BAA-894 5549164 YP_001437399.1 CDS ESA_01301 NC_009778.1 1263551 1264099 D expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 1263551..1264099 Cronobacter sakazakii ATCC BAA-894 5549182 YP_001437400.1 CDS ESA_01302 NC_009778.1 1264185 1264985 D KEGG: eci:UTI89_C2121 1.3e-122 fliY; cystine-binding periplasmic protein precursor K02030:K02424; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: extracellular, including cell wall, score: 9; cystine transporter subunit 1264185..1264985 Cronobacter sakazakii ATCC BAA-894 5549073 YP_001437401.1 CDS ESA_01303 NC_009778.1 1264958 1265083 D Psort location: cytoplasmic, score: 23; hypothetical protein 1264958..1265083 Cronobacter sakazakii ATCC BAA-894 5549030 YP_001437402.1 CDS ESA_01304 NC_009778.1 1265080 1266072 D catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 1265080..1266072 Cronobacter sakazakii ATCC BAA-894 5549040 YP_001437403.1 CDS ESA_01305 NC_009778.1 1266096 1266764 D KEGG: hpa:HPAG1_0922 5.1e-41 amino acid ABC transporter, permease protein; COG: COG0765 ABC-type amino acid transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1266096..1266764 Cronobacter sakazakii ATCC BAA-894 5549045 YP_001437404.1 CDS ESA_01306 NC_009778.1 1266761 1267513 D KEGG: ecj:JW1902 1.2e-114 yecC; predicted transporter subunit K02028; COG: COG1126 ABC-type polar amino acid transport system, ATPase component; Psort location: cytoplasmic, score: 23; putative amino-acid ABC transporter ATP-binding protein YecC 1266761..1267513 Cronobacter sakazakii ATCC BAA-894 5549034 YP_001437405.1 CDS ESA_01307 NC_009778.1 1267766 1268491 D regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 1267766..1268491 Cronobacter sakazakii ATCC BAA-894 5549049 YP_001437406.1 CDS ESA_01308 NC_009778.1 1268565 1268789 R COG: NOG13894 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1268565..1268789) Cronobacter sakazakii ATCC BAA-894 5549029 YP_001437407.1 CDS ESA_01309 NC_009778.1 1269273 1269929 D in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1269273..1269929 Cronobacter sakazakii ATCC BAA-894 5549058 YP_001437408.1 CDS uvrC NC_009778.1 1269926 1271758 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1269926..1271758 Cronobacter sakazakii ATCC BAA-894 5549013 YP_001437409.1 CDS ESA_01311 NC_009778.1 1271815 1272363 D KEGG: stt:t0931 1.6e-85 pgsA; phosphotidylglycerophosphate synthetase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: endoplasmic reticulum, score: 9; phosphatidylglycerophosphate synthetase 1271815..1272363 Cronobacter sakazakii ATCC BAA-894 5550226 YP_001437411.1 CDS ESA_01314 NC_009778.1 1272887 1272997 D Psort location: cytoplasmic, score: 23; hypothetical protein 1272887..1272997 Cronobacter sakazakii ATCC BAA-894 5549856 YP_001437412.1 CDS ESA_01316 NC_009778.1 1273202 1273804 D KEGG: btk:BT9727_2565 4.1e-23 acetyltransferase, GNAT family K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: mitochondrial, score: 23; hypothetical protein 1273202..1273804 Cronobacter sakazakii ATCC BAA-894 5550683 YP_001437413.1 CDS ESA_01317 NC_009778.1 1273833 1275041 R COG: COG0814 Amino acid permeases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1273833..1275041) Cronobacter sakazakii ATCC BAA-894 5550667 YP_001437414.1 CDS ESA_01318 NC_009778.1 1275279 1275776 R cytoplasmic iron storage protein; ferritin complement(1275279..1275776) Cronobacter sakazakii ATCC BAA-894 5551180 YP_001437415.1 CDS ESA_01319 NC_009778.1 1275920 1276087 D Psort location: nuclear, score: 23; hypothetical protein 1275920..1276087 Cronobacter sakazakii ATCC BAA-894 5551614 YP_001437416.1 CDS ESA_01320 NC_009778.1 1276039 1276419 R COG: NOG11332 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1276039..1276419) Cronobacter sakazakii ATCC BAA-894 5549703 YP_001437417.1 CDS ESA_01321 NC_009778.1 1276612 1277922 D KEGG: vpa:VPA0675 0.0079 torS; sensor protein TorS K07647; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1276612..1277922 Cronobacter sakazakii ATCC BAA-894 5549035 YP_001437418.1 CDS ESA_01322 NC_009778.1 1278060 1278698 D KEGG: stm:STM1933 6.0e-102 hypothetical protein K01806; COG: COG0698 Ribose 5-phosphate isomerase RpiB; Psort location: cytoplasmic, score: 23; hypothetical protein 1278060..1278698 Cronobacter sakazakii ATCC BAA-894 5549191 YP_001437419.1 CDS ESA_01323 NC_009778.1 1278738 1280159 R KEGG: ani:AN1180.2 3.2e-07 hypothetical protein K04428; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(1278738..1280159) Cronobacter sakazakii ATCC BAA-894 5549119 YP_001437420.1 CDS ESA_01324 NC_009778.1 1280402 1280677 D COG: NOG15359 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1280402..1280677 Cronobacter sakazakii ATCC BAA-894 5549134 YP_001437421.1 CDS ESA_01325 NC_009778.1 1280703 1281305 R COG: COG1280 Putative threonine efflux protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1280703..1281305) Cronobacter sakazakii ATCC BAA-894 5550977 YP_001437422.1 CDS ESA_01326 NC_009778.1 1281343 1282215 R KEGG: bha:BH0394 8.8e-09 adaA; methylphosphotriester-DNA alkyltransferase (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1281343..1282215) Cronobacter sakazakii ATCC BAA-894 5551113 YP_001437423.1 CDS ESA_01327 NC_009778.1 1282284 1283627 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(1282284..1283627) Cronobacter sakazakii ATCC BAA-894 5550805 YP_001437424.1 CDS ESA_01328 NC_009778.1 1283829 1284329 R COG: COG1528 Ferritin-like protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1283829..1284329) Cronobacter sakazakii ATCC BAA-894 5551355 YP_001437425.1 CDS ESA_01329 NC_009778.1 1284693 1285304 D COG: COG4297 Uncharacterized protein containing double-stranded beta helix domain; Psort location: cytoplasmic, score: 23; hypothetical protein 1284693..1285304 Cronobacter sakazakii ATCC BAA-894 5549330 YP_001437426.1 CDS ESA_01330 NC_009778.1 1285593 1286582 D KEGG: aha:AHA_1903 6.0e-141 L-arabinose ABC transporter, periplasmic L-arabinose-binding protein; COG: COG1879 ABC-type sugar transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1285593..1286582 Cronobacter sakazakii ATCC BAA-894 5549354 YP_001437427.1 CDS ESA_01332 NC_009778.1 1285644 1286660 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1285644..1286660) Cronobacter sakazakii ATCC BAA-894 5549364 YP_001437428.1 CDS araG NC_009778.1 1286645 1288159 D Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1286645..1288159 Cronobacter sakazakii ATCC BAA-894 5551533 YP_001437429.1 CDS araH NC_009778.1 1288245 1289153 D Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease protein 1288245..1289153 Cronobacter sakazakii ATCC BAA-894 5551520 YP_001437430.1 CDS ESA_01334 NC_009778.1 1289330 1290130 D biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1289330..1290130 Cronobacter sakazakii ATCC BAA-894 5551541 YP_001437431.1 CDS ESA_01335 NC_009778.1 1290105 1291529 D KEGG: ssn:SSO_1221 3.3e-220 otsA; trehalose-6-phosphate synthase K00697; COG: COG0380 Trehalose-6-phosphate synthase; Psort location: cytoplasmic, score: 23; trehalose-6-phosphate synthase 1290105..1291529 Cronobacter sakazakii ATCC BAA-894 5551440 YP_001437432.1 CDS ESA_01336 NC_009778.1 1291573 1291995 R ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC complement(1291573..1291995) Cronobacter sakazakii ATCC BAA-894 5551560 YP_001437433.1 CDS ESA_01337 NC_009778.1 1292799 1293158 D with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 1292799..1293158 Cronobacter sakazakii ATCC BAA-894 5551634 YP_001437434.1 CDS ESA_01338 NC_009778.1 1293162 1293743 D With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1293162..1293743 Cronobacter sakazakii ATCC BAA-894 5552450 YP_001437435.1 CDS ESA_01339 NC_009778.1 1293752 1294762 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1293752..1294762 Cronobacter sakazakii ATCC BAA-894 5552364 YP_001437436.1 CDS motB NC_009778.1 1294759 1295691 D with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1294759..1295691 Cronobacter sakazakii ATCC BAA-894 5552189 YP_001437437.1 CDS ESA_01341 NC_009778.1 1295702 1297708 D chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1295702..1297708 Cronobacter sakazakii ATCC BAA-894 5551518 YP_001437438.1 CDS ESA_01342 NC_009778.1 1297737 1298240 D KEGG: eci:UTI89_C2090 2.1e-74 cheW; CheW positive regulator of CheA protein activity K03408; COG: COG0835 Chemotaxis signal transduction protein; Psort location: cytoplasmic, score: 23; purine-binding chemotaxis protein 1297737..1298240 Cronobacter sakazakii ATCC BAA-894 5551581 YP_001437439.1 CDS ESA_01343 NC_009778.1 1298637 1299203 D KEGG: chu:CHU_0838 0.0026 CHU large protein; uncharacterized K01238; COG: COG5430 Uncharacterized secreted protein; Psort location: mitochondrial, score: 23; hypothetical protein 1298637..1299203 Cronobacter sakazakii ATCC BAA-894 5551413 YP_001437440.1 CDS ESA_01344 NC_009778.1 1299221 1299775 D COG: COG5430 Uncharacterized secreted protein; Psort location: mitochondrial, score: 23; hypothetical protein 1299221..1299775 Cronobacter sakazakii ATCC BAA-894 5549186 YP_001437441.1 CDS ESA_01345 NC_009778.1 1299792 1300550 D COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: cytoplasmic, score: 23; hypothetical protein 1299792..1300550 Cronobacter sakazakii ATCC BAA-894 5549109 YP_001437442.1 CDS ESA_01346 NC_009778.1 1300529 1302919 D COG: COG3188 P pilus assembly protein, porin PapC; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1300529..1302919 Cronobacter sakazakii ATCC BAA-894 5549104 YP_001437443.1 CDS ESA_01347 NC_009778.1 1302916 1303869 D COG: COG5430 Uncharacterized secreted protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1302916..1303869 Cronobacter sakazakii ATCC BAA-894 5549136 YP_001437444.1 CDS ESA_01348 NC_009778.1 1303966 1305636 D KEGG: vpa:VPA0675 5.0e-06 torS; sensor protein TorS K07647; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1303966..1305636 Cronobacter sakazakii ATCC BAA-894 5549189 YP_001437445.1 CDS ESA_01349 NC_009778.1 1305673 1305876 D Psort location: nuclear, score: 23; hypothetical protein 1305673..1305876 Cronobacter sakazakii ATCC BAA-894 5549158 YP_001437446.1 CDS ESA_01350 NC_009778.1 1305962 1306783 D methylates the MCP; chemotaxis methyltransferase CheR 1305962..1306783 Cronobacter sakazakii ATCC BAA-894 5549143 YP_001437447.1 CDS ESA_01351 NC_009778.1 1306780 1307829 D regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1306780..1307829 Cronobacter sakazakii ATCC BAA-894 5549171 YP_001437448.1 CDS ESA_01352 NC_009778.1 1307847 1308236 D chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1307847..1308236 Cronobacter sakazakii ATCC BAA-894 5549120 YP_001437449.1 CDS ESA_01353 NC_009778.1 1308247 1308888 D cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1308247..1308888 Cronobacter sakazakii ATCC BAA-894 5549205 YP_001437450.1 CDS ESA_01354 NC_009778.1 1309123 1310169 D COG: COG1377 Flagellar biosynthesis pathway, component FlhB; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1309123..1310169 Cronobacter sakazakii ATCC BAA-894 5549121 YP_001437451.1 CDS flhA NC_009778.1 1310162 1312240 D membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1310162..1312240 Cronobacter sakazakii ATCC BAA-894 5549129 YP_001437452.1 CDS ESA_01356 NC_009778.1 1312240 1312641 D COG: NOG12148 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1312240..1312641 Cronobacter sakazakii ATCC BAA-894 5549172 YP_001437453.1 CDS ESA_01357 NC_009778.1 1312811 1314502 D KEGG: eci:UTI89_C4210 3.4e-16 yicJ; hypothetical symporter YicJ K03292; COG: COG2211 Na+/melibiose symporter and related transporters; Psort location: plasma membrane, score: 23; hypothetical protein 1312811..1314502 Cronobacter sakazakii ATCC BAA-894 5549140 YP_001437454.1 CDS ESA_01358 NC_009778.1 1314502 1315641 D COG: COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 1314502..1315641 Cronobacter sakazakii ATCC BAA-894 5549155 YP_001437455.1 CDS ESA_01359 NC_009778.1 1316244 1316870 D COG: NOG06782 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1316244..1316870 Cronobacter sakazakii ATCC BAA-894 5549194 YP_001437456.1 CDS argS NC_009778.1 1316937 1318670 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(1316937..1318670) Cronobacter sakazakii ATCC BAA-894 5549154 YP_001437457.1 CDS ESA_01361 NC_009778.1 1318856 1319419 D COG: COG3102 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1318856..1319419 Cronobacter sakazakii ATCC BAA-894 5549056 YP_001437458.1 CDS ESA_01362 NC_009778.1 1319569 1320111 D COG: COG5637 Predicted integral membrane protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1319569..1320111 Cronobacter sakazakii ATCC BAA-894 5549127 YP_001437459.1 CDS ESA_01363 NC_009778.1 1320115 1321281 D KEGG: ava:Ava_C0165 4.0e-128 zinc-containing alcohol dehydrogenase superfamily; COG: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 1320115..1321281 Cronobacter sakazakii ATCC BAA-894 5548923 YP_001437460.1 CDS ESA_01364 NC_009778.1 1321271 1322317 R KEGG: dar:Daro_4129 3.8e-84 aminotransferase, class I and II K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1321271..1322317) Cronobacter sakazakii ATCC BAA-894 5549197 YP_001437461.1 CDS ESA_01365 NC_009778.1 1322322 1322927 D KEGG: cef:CE1276 0.0077 putative arginyl-tRNA synthetase K01887; COG: COG3142 Uncharacterized protein involved in copper resistance; Psort location: cytoplasmic, score: 23; copper homeostasis protein CutC 1322322..1322927 Cronobacter sakazakii ATCC BAA-894 5549151 YP_001437462.1 CDS ESA_01366 NC_009778.1 1323091 1323336 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1323091..1323336) Cronobacter sakazakii ATCC BAA-894 5549115 YP_001437463.1 CDS ESA_01367 NC_009778.1 1323337 1324827 D KEGG: mbo:Mb0358 1.0e-76 dnaK; probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kda protein) (HSP70) K04043; COG: COG0443 Molecular chaperone; Psort location: cytoplasmic, score: 23; hypothetical protein 1323337..1324827 Cronobacter sakazakii ATCC BAA-894 5549137 YP_001437464.1 CDS ESA_01368 NC_009778.1 1324827 1326476 D COG: NOG21760 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1324827..1326476 Cronobacter sakazakii ATCC BAA-894 5549070 YP_001437465.1 CDS ESA_01369 NC_009778.1 1326616 1327062 D KEGG: mlo:mlr3017 0.0017 5'-nucleotidase K01081; COG: COG1652 Uncharacterized protein containing LysM domain; Psort location: cytoplasmic, score: 23; LysM domain/BON superfamily protein 1326616..1327062 Cronobacter sakazakii ATCC BAA-894 5549202 YP_001437466.1 CDS ESA_01370 NC_009778.1 1327099 1328070 R KEGG: eci:UTI89_C2075 1.1e-143 yecP; hypothetical protein K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1327099..1328070) Cronobacter sakazakii ATCC BAA-894 5549067 YP_001437467.1 CDS ESA_01371 NC_009778.1 1328067 1328810 R KEGG: eci:UTI89_C2074 5.4e-117 yecO; hypothetical protein K00559; COG: COG0500 SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1328067..1328810) Cronobacter sakazakii ATCC BAA-894 5549135 YP_001437468.1 CDS ESA_01372 NC_009778.1 1328851 1329246 R KEGG: hsa:4056 3.4e-05 LTC4S; leukotriene C4 synthase K00807; COG: COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1328851..1329246) Cronobacter sakazakii ATCC BAA-894 5549105 YP_001437469.1 CDS ESA_01373 NC_009778.1 1329314 1330132 R COG: COG1801 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1329314..1330132) Cronobacter sakazakii ATCC BAA-894 5549213 YP_001437470.1 CDS ESA_01374 NC_009778.1 1330129 1330695 R KEGG: eci:UTI89_C2071 2.7e-74 yecD; hypothetical protein; COG: COG1335 Amidases related to nicotinamidase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1330129..1330695) Cronobacter sakazakii ATCC BAA-894 5549224 YP_001437471.1 CDS ESA_01375 NC_009778.1 1330733 1330888 R Psort location: nuclear, score: 23; hypothetical protein complement(1330733..1330888) Cronobacter sakazakii ATCC BAA-894 5549183 YP_001437472.1 CDS aspS NC_009778.1 1330962 1332740 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1330962..1332740 Cronobacter sakazakii ATCC BAA-894 5549139 YP_001437473.1 CDS ntpA NC_009778.1 1332742 1333185 D converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1332742..1333185 Cronobacter sakazakii ATCC BAA-894 5549339 YP_001437474.1 CDS ESA_01378 NC_009778.1 1333213 1333953 D KEGG: eci:UTI89_C2068 2.6e-124 yebC; hypothetical protein K00975; COG: COG0217 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1333213..1333953 Cronobacter sakazakii ATCC BAA-894 5549304 YP_001437475.1 CDS ruvC NC_009778.1 1334042 1334563 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1334042..1334563 Cronobacter sakazakii ATCC BAA-894 5549259 YP_001437476.1 CDS ruvA NC_009778.1 1334709 1335320 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1334709..1335320 Cronobacter sakazakii ATCC BAA-894 5549283 YP_001437477.1 CDS ruvB NC_009778.1 1335329 1336339 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1335329..1336339 Cronobacter sakazakii ATCC BAA-894 5549247 YP_001437478.1 CDS znuB NC_009778.1 1336424 1337209 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component complement(1336424..1337209) Cronobacter sakazakii ATCC BAA-894 5549390 YP_001437479.1 CDS znuC NC_009778.1 1337206 1337961 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase complement(1337206..1337961) Cronobacter sakazakii ATCC BAA-894 5549308 YP_001437480.1 CDS znuA NC_009778.1 1338025 1338984 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component 1338025..1338984 Cronobacter sakazakii ATCC BAA-894 5549349 YP_001437481.1 CDS ESA_01385 NC_009778.1 1339063 1340331 D KEGG: stm:STM1890 5.5e-202 yebA; putative peptidase; COG: COG0739 Membrane proteins related to metalloendopeptidases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1339063..1340331 Cronobacter sakazakii ATCC BAA-894 5549298 YP_001437482.1 CDS ESA_01386 NC_009778.1 1340457 1341425 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1340457..1341425 Cronobacter sakazakii ATCC BAA-894 5549113 YP_001437483.1 CDS ESA_01387 NC_009778.1 1341493 1342935 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1341493..1342935) Cronobacter sakazakii ATCC BAA-894 5549178 YP_001437484.1 CDS ESA_01388 NC_009778.1 1343065 1343961 R Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR complement(1343065..1343961) Cronobacter sakazakii ATCC BAA-894 5549242 YP_001437485.1 CDS ESA_01389 NC_009778.1 1344285 1345760 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1344285..1345760 Cronobacter sakazakii ATCC BAA-894 5549343 YP_001437486.1 CDS ESA_01390 NC_009778.1 1345995 1347806 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1345995..1347806 Cronobacter sakazakii ATCC BAA-894 5549389 YP_001437487.1 CDS ESA_01391 NC_009778.1 1347865 1348503 D catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1347865..1348503 Cronobacter sakazakii ATCC BAA-894 5549313 YP_001437488.1 CDS purT NC_009778.1 1348557 1349690 R non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 complement(1348557..1349690) Cronobacter sakazakii ATCC BAA-894 5549355 YP_001437489.1 CDS ESA_01393 NC_009778.1 1349868 1350218 D COG: COG3141 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1349868..1350218 Cronobacter sakazakii ATCC BAA-894 5549276 YP_001437490.1 CDS ESA_01394 NC_009778.1 1350584 1350931 D secreted protein; unknown function; hypothetical protein 1350584..1350931 Cronobacter sakazakii ATCC BAA-894 5552256 YP_001437491.1 CDS ESA_01395 NC_009778.1 1351046 1351726 D COG: COG2979 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1351046..1351726 Cronobacter sakazakii ATCC BAA-894 5549251 YP_001437492.1 CDS ESA_01396 NC_009778.1 1351816 1353879 D PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1351816..1353879 Cronobacter sakazakii ATCC BAA-894 5549253 YP_001437493.1 CDS ESA_01397 NC_009778.1 1353876 1354538 R 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X complement(1353876..1354538) Cronobacter sakazakii ATCC BAA-894 5549237 YP_001437494.1 CDS ESA_01398 NC_009778.1 1354611 1354841 R KEGG: ece:Z2891 2.2e-31 holE; DNA polymerase III theta subunit K02345; Psort location: cytoplasmic, score: 23; DNA polymerase III subunit theta complement(1354611..1354841) Cronobacter sakazakii ATCC BAA-894 5549316 YP_001437495.1 CDS ESA_01399 NC_009778.1 1354979 1355362 D COG: COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; Psort location: cytoplasmic, score: 23; hypothetical protein 1354979..1355362 Cronobacter sakazakii ATCC BAA-894 5549356 YP_001437496.1 CDS ESA_01400 NC_009778.1 1355367 1356236 D COG: COG1276 Putative copper export protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1355367..1356236 Cronobacter sakazakii ATCC BAA-894 5549414 YP_001437497.1 CDS ESA_01401 NC_009778.1 1356251 1356589 D COG: NOG09766 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1356251..1356589 Cronobacter sakazakii ATCC BAA-894 5549245 YP_001437498.1 CDS ESA_01404 NC_009778.1 1357289 1357618 D Psort location: cytoplasmic, score: 23; hypothetical protein 1357289..1357618 Cronobacter sakazakii ATCC BAA-894 5549249 YP_001437499.1 CDS ESA_01405 NC_009778.1 1357451 1357597 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1357451..1357597) Cronobacter sakazakii ATCC BAA-894 5552262 YP_001437500.1 CDS ESA_01406 NC_009778.1 1357608 1357907 D COG: NOG37778 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1357608..1357907 Cronobacter sakazakii ATCC BAA-894 5551707 YP_001437501.1 CDS ESA_01407 NC_009778.1 1357967 1358149 D Psort location: cytoplasmic, score: 23; hypothetical protein 1357967..1358149 Cronobacter sakazakii ATCC BAA-894 5549900 YP_001437502.1 CDS ESA_01409 NC_009778.1 1358244 1358363 R Psort location: nuclear, score: 23; hypothetical protein complement(1358244..1358363) Cronobacter sakazakii ATCC BAA-894 5549905 YP_001437503.1 CDS ESA_01408 NC_009778.1 1358253 1358345 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1358253..1358345 Cronobacter sakazakii ATCC BAA-894 5549944 YP_001437504.1 CDS ESA_01410 NC_009778.1 1358366 1358497 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1358366..1358497) Cronobacter sakazakii ATCC BAA-894 5549927 YP_001437505.1 CDS ESA_01411 NC_009778.1 1358703 1359347 D KEGG: spt:SPA1020 1.5e-57 pphA; serine/threonine protein phosphatase 1 K07313; COG: COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; Psort location: cytoplasmic, score: 23; hypothetical protein 1358703..1359347 Cronobacter sakazakii ATCC BAA-894 5549950 YP_001437506.1 CDS ESA_01412 NC_009778.1 1359348 1359539 R COG: NOG12164 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1359348..1359539) Cronobacter sakazakii ATCC BAA-894 5549969 YP_001437507.1 CDS ESA_01413 NC_009778.1 1359664 1359903 R COG: NOG13883 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1359664..1359903) Cronobacter sakazakii ATCC BAA-894 5549988 YP_001437508.1 CDS yebU NC_009778.1 1360016 1361410 R in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF complement(1360016..1361410) Cronobacter sakazakii ATCC BAA-894 5550001 YP_001437509.1 CDS ESA_01415 NC_009778.1 1361536 1364169 R COG: COG3008 Paraquat-inducible protein B; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1361536..1364169) Cronobacter sakazakii ATCC BAA-894 5550005 YP_001437510.1 CDS ESA_01417 NC_009778.1 1364138 1365421 R COG: COG2995 Uncharacterized paraquat-inducible protein A; Psort location: plasma membrane, score: 23; hypothetical protein complement(1364138..1365421) Cronobacter sakazakii ATCC BAA-894 5551997 YP_001437511.1 CDS ESA_01416 NC_009778.1 1365371 1365496 D Psort location: cytoplasmic, score: 23; hypothetical protein 1365371..1365496 Cronobacter sakazakii ATCC BAA-894 5550026 YP_001437512.1 CDS ESA_01418 NC_009778.1 1365550 1366044 D COG: COG1956 GAF domain-containing protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1365550..1366044 Cronobacter sakazakii ATCC BAA-894 5550015 YP_001437513.1 CDS ESA_01419 NC_009778.1 1366145 1366837 D affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 1366145..1366837 Cronobacter sakazakii ATCC BAA-894 5550033 YP_001437514.1 CDS ESA_01420 NC_009778.1 1366857 1368905 D Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1366857..1368905 Cronobacter sakazakii ATCC BAA-894 5550036 YP_001437515.1 CDS ESA_01421 NC_009778.1 1369100 1369981 D putative metalloprotease; heat shock protein HtpX 1369100..1369981 Cronobacter sakazakii ATCC BAA-894 5550039 YP_001437516.1 CDS ESA_01423 NC_009778.1 1370155 1370286 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1370155..1370286) Cronobacter sakazakii ATCC BAA-894 5550040 YP_001437517.1 CDS ESA_01422 NC_009778.1 1370234 1371025 D COG: COG1414 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1370234..1371025 Cronobacter sakazakii ATCC BAA-894 5550047 YP_001437518.1 CDS ESA_01424 NC_009778.1 1371082 1371321 R COG: NOG13884 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1371082..1371321) Cronobacter sakazakii ATCC BAA-894 5550045 YP_001437519.1 CDS ESA_01425 NC_009778.1 1371480 1371623 D COG: NOG18120 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1371480..1371623 Cronobacter sakazakii ATCC BAA-894 5550051 YP_001437520.1 CDS ESA_01426 NC_009778.1 1371639 1371980 D COG: NOG11327 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 1371639..1371980 Cronobacter sakazakii ATCC BAA-894 5550057 YP_001437521.1 CDS ESA_01427 NC_009778.1 1372001 1373008 D KEGG: xla:379989 0.00035 cmah-prov; cytidine monophospho-N-acetylneuraminic acid hydroxylase K08080; COG: COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Psort location: cytoplasmic, score: 23; hypothetical protein 1372001..1373008 Cronobacter sakazakii ATCC BAA-894 5550059 YP_001437522.1 CDS ESA_01428 NC_009778.1 1373622 1373894 D COG: COG1278 Cold shock proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 1373622..1373894 Cronobacter sakazakii ATCC BAA-894 5550064 YP_001437523.1 CDS ESA_01429 NC_009778.1 1374048 1374863 D KEGG: eci:UTI89_C2020 5.7e-97 yebH; ribosomal RNA large subunit methyltransferase A K00563; COG: COG0500 SAM-dependent methyltransferases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1374048..1374863 Cronobacter sakazakii ATCC BAA-894 5550068 YP_001437524.1 CDS ESA_01430 NC_009778.1 1374860 1375423 R COG: COG1971 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1374860..1375423) Cronobacter sakazakii ATCC BAA-894 5550069 YP_001437525.1 CDS ESA_01431 NC_009778.1 1375757 1375882 D Psort location: cytoplasmic, score: 23; hypothetical protein 1375757..1375882 Cronobacter sakazakii ATCC BAA-894 5550071 YP_001437526.1 CDS ESA_01432 NC_009778.1 1375799 1376257 R COG: COG4811 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1375799..1376257) Cronobacter sakazakii ATCC BAA-894 5552338 YP_001437527.1 CDS ESA_01433 NC_009778.1 1376318 1377169 R hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID complement(1376318..1377169) Cronobacter sakazakii ATCC BAA-894 5552282 YP_001437528.1 CDS ESA_01434 NC_009778.1 1377182 1377982 R KEGG: eci:UTI89_C2015 1.4e-125 manY; PTS enzyme IIC, mannose-specific K02795; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1377182..1377982) Cronobacter sakazakii ATCC BAA-894 5550082 YP_001437529.1 CDS ESA_01435 NC_009778.1 1378047 1379009 R KEGG: stm:STM1830 4.9e-155 manX; Sugar Specific PTS family, mannose-specific enzyme IIAB K02793:K02794; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1378047..1379009) Cronobacter sakazakii ATCC BAA-894 5550087 YP_001437530.1 CDS ESA_01436 NC_009778.1 1379143 1379277 D Psort location: mitochondrial, score: 23; hypothetical protein 1379143..1379277 Cronobacter sakazakii ATCC BAA-894 5550091 YP_001437531.1 CDS ESA_01437 NC_009778.1 1379472 1381031 D KEGG: eci:UTI89_C0656 5.4e-22 ybeX; putative transport protein K06189; COG: COG1253 Hemolysins and related proteins containing CBS domains; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1379472..1381031 Cronobacter sakazakii ATCC BAA-894 5550111 YP_001437532.1 CDS ESA_01438 NC_009778.1 1381035 1382633 R KEGG: shn:Shewana3_3829 5.7e-32 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(1381035..1382633) Cronobacter sakazakii ATCC BAA-894 5550155 YP_001437533.1 CDS ESA_01439 NC_009778.1 1382765 1384186 R KEGG: ecc:c2219 7.4e-223 sdaA; L-serine dehydratase 1 K01752; COG: COG1760 L-serine deaminase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1382765..1384186) Cronobacter sakazakii ATCC BAA-894 5550158 YP_001437534.1 CDS ESA_01440 NC_009778.1 1384301 1384879 R KEGG: gbe:GbCGDNIH1_1634 8.5e-32 coA pyrophosphatase K01529; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1384301..1384879) Cronobacter sakazakii ATCC BAA-894 5550129 YP_001437535.1 CDS ESA_01441 NC_009778.1 1384882 1386246 R KEGG: stt:t1053 4.0e-176 pabB; para-aminobenzoate synthase component I K01665; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1384882..1386246) Cronobacter sakazakii ATCC BAA-894 5550099 YP_001437536.1 CDS ESA_01442 NC_009778.1 1386337 1386519 D COG: COG3140 Uncharacterized protein conserved in bacteria; Psort location: cytoskeletal, score: 9; hypothetical protein 1386337..1386519 Cronobacter sakazakii ATCC BAA-894 5550097 YP_001437537.1 CDS ESA_01443 NC_009778.1 1386662 1387669 D KEGG: yps:YPTB1971 1.3e-122 putative 3-oxoacyl-(acyl-carrier-protein) synthase III K00648; COG: COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; Psort location: cytoplasmic, score: 23; hypothetical protein 1386662..1387669 Cronobacter sakazakii ATCC BAA-894 5550084 YP_001437538.1 CDS ESA_01444 NC_009778.1 1387666 1388670 D KEGG: eci:UTI89_C0871 8.0e-75 ybjS; hypothetical protein YbjS K00067; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein 1387666..1388670 Cronobacter sakazakii ATCC BAA-894 5550058 YP_001437539.1 CDS ESA_01445 NC_009778.1 1388671 1389477 D KEGG: fnu:FN1848 3.5e-13 metal dependent hydrolase; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: cytoplasmic, score: 23; hypothetical protein 1388671..1389477 Cronobacter sakazakii ATCC BAA-894 5550014 YP_001437540.1 CDS ESA_01446 NC_009778.1 1389474 1390760 D KEGG: mag:amb1245 1.6e-07 coenzyme F390 synthetase K01912; COG: COG1541 Coenzyme F390 synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein 1389474..1390760 Cronobacter sakazakii ATCC BAA-894 5551717 YP_001437541.1 CDS ESA_01447 NC_009778.1 1390757 1391374 D KEGG: reh:H16_A2091 2.2e-07 membrane-associated Ser/Thr and Tyr protein phosphatase (dual specificity) K01090; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1390757..1391374 Cronobacter sakazakii ATCC BAA-894 5549725 YP_001437542.1 CDS ESA_01448 NC_009778.1 1391367 1392488 D KEGG: msm:MSMEG_2812 7.5e-24 C-5 sterol desaturase K00258; COG: COG3000 Sterol desaturase; Psort location: plasma membrane, score: 23; hypothetical protein 1391367..1392488 Cronobacter sakazakii ATCC BAA-894 5549741 YP_001437543.1 CDS ESA_01449 NC_009778.1 1392481 1393572 D KEGG: cvi:CV2452 1.5e-71 probable linoleoyl-CoA desaturase K00508; COG: COG3239 Fatty acid desaturase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1392481..1393572 Cronobacter sakazakii ATCC BAA-894 5549753 YP_001437544.1 CDS ESA_01450 NC_009778.1 1393562 1394671 D KEGG: cvi:CV2452 1.5e-73 probable linoleoyl-CoA desaturase K00508; COG: COG3239 Fatty acid desaturase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1393562..1394671 Cronobacter sakazakii ATCC BAA-894 5549777 YP_001437545.1 CDS ESA_01451 NC_009778.1 1394681 1395025 R KEGG: mxa:MXAN_0920 0.00049 2-aminomuconate deaminase; COG: COG0251 Putative translation initiation inhibitor, yjgF family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1394681..1395025) Cronobacter sakazakii ATCC BAA-894 5549441 YP_001437546.1 CDS ESA_01452 NC_009778.1 1395156 1397066 D KEGG: sty:STY1951 1.3e-298 putative ATP-dependent helicase K03722; COG: COG1199 Rad3-related DNA helicases; Psort location: cytoplasmic, score: 23; hypothetical protein 1395156..1397066 Cronobacter sakazakii ATCC BAA-894 5549751 YP_001437547.1 CDS ESA_01453 NC_009778.1 1397136 1397831 D KEGG: ecp:ECP_1750 3.0e-100 hypothetical protease YeaZ K01423; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: cytoplasmic, score: 23; hypothetical protein 1397136..1397831 Cronobacter sakazakii ATCC BAA-894 5549773 YP_001437548.1 CDS ESA_01454 NC_009778.1 1397872 1398456 D COG: COG3065 Starvation-inducible outer membrane lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1397872..1398456 Cronobacter sakazakii ATCC BAA-894 5549802 YP_001437549.1 CDS ESA_01455 NC_009778.1 1398629 1400347 D Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1398629..1400347 Cronobacter sakazakii ATCC BAA-894 5549768 YP_001437550.1 CDS ESA_01456 NC_009778.1 1400430 1401539 D KEGG: ecc:c2208 9.1e-154 rnd; ribonuclease D K03684; COG: COG0349 Ribonuclease D; Psort location: cytoplasmic, score: 23; ribonuclease D 1400430..1401539 Cronobacter sakazakii ATCC BAA-894 5549826 YP_001437551.1 CDS minE NC_009778.1 1401643 1401909 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1401643..1401909) Cronobacter sakazakii ATCC BAA-894 5552197 YP_001437552.1 CDS ESA_01458 NC_009778.1 1401913 1402725 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1401913..1402725) Cronobacter sakazakii ATCC BAA-894 5549835 YP_001437553.1 CDS minC NC_009778.1 1402750 1403442 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1402750..1403442) Cronobacter sakazakii ATCC BAA-894 5549866 YP_001437554.1 CDS ESA_01460 NC_009778.1 1403568 1403843 D COG: COG3100 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 1403568..1403843 Cronobacter sakazakii ATCC BAA-894 5549872 YP_001437555.1 CDS ESA_01461 NC_009778.1 1403960 1404619 D KEGG: reu:Reut_A0332 1.2e-39 5-carboxymethyl-2-hydroxymuconate delta-isomerase K01826; COG: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); Psort location: cytoplasmic, score: 23; hypothetical protein 1403960..1404619 Cronobacter sakazakii ATCC BAA-894 5548773 YP_001437556.1 CDS ESA_01462 NC_009778.1 1404708 1405154 D COG: COG2983 Uncharacterized conserved protein; Psort location: mitochondrial, score: 23; hypothetical protein 1404708..1405154 Cronobacter sakazakii ATCC BAA-894 5548556 YP_001437557.1 CDS ESA_01463 NC_009778.1 1405599 1405856 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1405599..1405856) Cronobacter sakazakii ATCC BAA-894 5548582 YP_001437558.1 CDS ESA_01464 NC_009778.1 1406295 1406897 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1406295..1406897) Cronobacter sakazakii ATCC BAA-894 5552211 YP_001437559.1 CDS nhaB NC_009778.1 1406965 1408527 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1406965..1408527) Cronobacter sakazakii ATCC BAA-894 5551457 YP_001437560.1 CDS ESA_01466 NC_009778.1 1408531 1408698 D Psort location: cytoplasmic, score: 23; hypothetical protein 1408531..1408698 Cronobacter sakazakii ATCC BAA-894 5551406 YP_001437561.1 CDS ESA_01467 NC_009778.1 1408739 1409458 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1408739..1409458 Cronobacter sakazakii ATCC BAA-894 5551442 YP_001437562.1 CDS ESA_01468 NC_009778.1 1409519 1411084 R COG: COG2719 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; SpoVR family protein complement(1409519..1411084) Cronobacter sakazakii ATCC BAA-894 5551449 YP_001437563.1 CDS ESA_01469 NC_009778.1 1411378 1412676 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1411378..1412676 Cronobacter sakazakii ATCC BAA-894 5552319 YP_001437564.1 CDS dadX NC_009778.1 1412689 1413759 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1412689..1413759 Cronobacter sakazakii ATCC BAA-894 5548147 YP_001437565.1 CDS ESA_01471 NC_009778.1 1413832 1415562 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1413832..1415562) Cronobacter sakazakii ATCC BAA-894 5552071 YP_001437566.1 CDS ESA_01472 NC_009778.1 1416111 1416404 D COG: COG5470 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1416111..1416404 Cronobacter sakazakii ATCC BAA-894 5548148 YP_001437567.1 CDS ESA_01473 NC_009778.1 1416792 1416902 D Psort location: cytoplasmic, score: 23; hypothetical protein 1416792..1416902 Cronobacter sakazakii ATCC BAA-894 5550185 YP_001437568.1 CDS ldcA NC_009778.1 1417244 1418188 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1417244..1418188) Cronobacter sakazakii ATCC BAA-894 5550188 YP_001437569.1 CDS ESA_01475 NC_009778.1 1418336 1418929 D KEGG: stm:STM1799 1.2e-82 emtA; membrane-bound lytic murein transglycosylase E K08308; COG: COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); Psort location: cytoplasmic, score: 23; hypothetical protein 1418336..1418929 Cronobacter sakazakii ATCC BAA-894 5549648 YP_001437570.1 CDS ESA_01476 NC_009778.1 1418930 1419661 R COG: COG5581 Predicted glycosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1418930..1419661) Cronobacter sakazakii ATCC BAA-894 5550318 YP_001437571.1 CDS ESA_01477 NC_009778.1 1419879 1420133 D KEGG: cjk:jk1171 0.00057 cdsA; phosphatidate cytidylyltransferase K00981; COG: COG2261 Predicted membrane protein; Psort location: extracellular, including cell wall, score: 23; hypothetical protein 1419879..1420133 Cronobacter sakazakii ATCC BAA-894 5550324 YP_001437572.1 CDS ESA_01478 NC_009778.1 1420205 1422382 R KEGG: sgl:SG1838 3.9e-27 putative mannonate dehydratase K01686; COG: COG1629 Outer membrane receptor proteins, mostly Fe transport; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1420205..1422382) Cronobacter sakazakii ATCC BAA-894 5550330 YP_001437573.1 CDS treA NC_009778.1 1422569 1424503 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1422569..1424503) Cronobacter sakazakii ATCC BAA-894 5551857 YP_001437574.1 CDS ESA_01481 NC_009778.1 1424641 1426158 R KEGG: bur:Bcep18194_B3074 4.0e-96 transcriptional regulator, GntR family with aminotransferase activity K00375; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1424641..1426158) Cronobacter sakazakii ATCC BAA-894 5552022 YP_001437575.1 CDS ESA_01480 NC_009778.1 1426157 1426636 D KEGG: msm:MSMEG_6370 5.7e-26 pcaC; 4-carboxymuconolactone decarboxylase K01607; COG: COG2128 Uncharacterized conserved protein; Psort location: mitochondrial, score: 23; hypothetical protein 1426157..1426636 Cronobacter sakazakii ATCC BAA-894 5552236 YP_001437576.1 CDS ESA_01482 NC_009778.1 1426894 1427601 D COG: COG3645 Uncharacterized phage-encoded protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1426894..1427601 Cronobacter sakazakii ATCC BAA-894 5551835 YP_001437577.1 CDS ESA_01483 NC_009778.1 1427758 1428354 R KEGG: eca:ECA0951 5.0e-66 probable NAD(P)H oxidoreductase K00355; COG: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); Psort location: cytoplasmic, score: 23; hypothetical protein complement(1427758..1428354) Cronobacter sakazakii ATCC BAA-894 5551904 YP_001437578.1 CDS ESA_01484 NC_009778.1 1428531 1429055 D COG: COG1309 Transcriptional regulator; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1428531..1429055 Cronobacter sakazakii ATCC BAA-894 5549391 YP_001437579.1 CDS ESA_01485 NC_009778.1 1429216 1430001 D COG: NOG11107 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1429216..1430001 Cronobacter sakazakii ATCC BAA-894 5549265 YP_001437580.1 CDS ESA_01486 NC_009778.1 1430100 1430771 R KEGG: pen:PSEEN4477 0.0019 secA; preprotein translocase SecA subunit; COG: COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1430100..1430771) Cronobacter sakazakii ATCC BAA-894 5549344 YP_001437581.1 CDS ESA_01487 NC_009778.1 1430956 1432134 D Psort location: cytoplasmic, score: 23; hypothetical protein 1430956..1432134 Cronobacter sakazakii ATCC BAA-894 5549329 YP_001437582.1 CDS ESA_01488 NC_009778.1 1430989 1432080 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1430989..1432080) Cronobacter sakazakii ATCC BAA-894 5549695 YP_001437583.1 CDS ESA_01489 NC_009778.1 1432220 1432804 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1432220..1432804) Cronobacter sakazakii ATCC BAA-894 5549376 YP_001437584.1 CDS ESA_01490 NC_009778.1 1433072 1433347 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1433072..1433347 Cronobacter sakazakii ATCC BAA-894 5549289 YP_001437585.1 CDS ESA_01491 NC_009778.1 1433480 1434526 D KEGG: syn:sll0794 2.7e-08 corR, merR, cobH, cbiC; cobalt-dependent transcriptional regulator (MerR (mercuric resistance operon regulatory protein)-like domain in N-terminal half), precorrin isomerase, Precorrin-8X methylmutase (in C-terminal half) K01833; COG: COG0789 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 1433480..1434526 Cronobacter sakazakii ATCC BAA-894 5549296 YP_001437586.1 CDS ESA_01492 NC_009778.1 1434528 1436207 R putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM complement(1434528..1436207) Cronobacter sakazakii ATCC BAA-894 5549307 YP_001437587.1 CDS ESA_01493 NC_009778.1 1436143 1436283 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1436143..1436283) Cronobacter sakazakii ATCC BAA-894 5549365 YP_001437588.1 CDS ESA_01494 NC_009778.1 1436329 1437294 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1436329..1437294) Cronobacter sakazakii ATCC BAA-894 5549341 YP_001437589.1 CDS ipk NC_009778.1 1437404 1438270 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1437404..1438270) Cronobacter sakazakii ATCC BAA-894 5549798 YP_001437590.1 CDS lolB NC_009778.1 1438270 1438938 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1438270..1438938) Cronobacter sakazakii ATCC BAA-894 5549346 YP_001437591.1 CDS hemA NC_009778.1 1438937 1440349 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1438937..1440349 Cronobacter sakazakii ATCC BAA-894 5549361 YP_001437592.1 CDS prfA NC_009778.1 1440387 1441469 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1440387..1441469 Cronobacter sakazakii ATCC BAA-894 5549306 YP_001437593.1 CDS ESA_01499 NC_009778.1 1441469 1442326 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1441469..1442326 Cronobacter sakazakii ATCC BAA-894 5549291 YP_001437594.1 CDS ESA_01500 NC_009778.1 1442333 1442728 D COG: COG3094 Uncharacterized protein conserved in bacteria; Psort location: plasma membrane, score: 23; hypothetical protein 1442333..1442728 Cronobacter sakazakii ATCC BAA-894 5549315 YP_001437595.1 CDS ESA_01501 NC_009778.1 1442725 1443534 D KEGG: nmu:Nmul_A1387 0.0058 thymidylate kinase K00943; COG: COG2912 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; putative transcriptional regulator 1442725..1443534 Cronobacter sakazakii ATCC BAA-894 5549284 YP_001437596.1 CDS ESA_01502 NC_009778.1 1443575 1444429 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1443575..1444429 Cronobacter sakazakii ATCC BAA-894 5549399 YP_001437597.1 CDS ESA_01503 NC_009778.1 1444680 1445783 R COG: COG0387 Ca2+/H+ antiporter; Psort location: plasma membrane, score: 23; calcium/sodium:proton antiporter complement(1444680..1445783) Cronobacter sakazakii ATCC BAA-894 5549392 YP_001437598.1 CDS chaB NC_009778.1 1446058 1446288 D in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1446058..1446288 Cronobacter sakazakii ATCC BAA-894 5549397 YP_001437599.1 CDS ESA_01505 NC_009778.1 1446527 1447204 D COG: COG3703 Uncharacterized protein involved in cation transport; Psort location: cytoplasmic, score: 23; hypothetical protein 1446527..1447204 Cronobacter sakazakii ATCC BAA-894 5549216 YP_001437600.1 CDS ESA_01506 NC_009778.1 1447235 1447480 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1447235..1447480) Cronobacter sakazakii ATCC BAA-894 5549290 YP_001437601.1 CDS ESA_01507 NC_009778.1 1447690 1449477 R KEGG: rha:RHA1_ro04742 1.9e-07 phoR; sensor kinase, two-component system K07636; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(1447690..1449477) Cronobacter sakazakii ATCC BAA-894 5549318 YP_001437602.1 CDS ESA_01508 NC_009778.1 1449625 1449996 R COG: COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1449625..1449996) Cronobacter sakazakii ATCC BAA-894 5551826 YP_001437603.1 CDS ESA_01509 NC_009778.1 1450050 1451252 D KEGG: xac:XAC2157 0.00084 cysG; uroporphyrin-III C-methyltransferase K02302; COG: COG3707 Response regulator with putative antiterminator output domain; Psort location: cytoplasmic, score: 23; hypothetical protein 1450050..1451252 Cronobacter sakazakii ATCC BAA-894 5549556 YP_001437604.1 CDS ESA_01510 NC_009778.1 1451992 1453242 D COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; Psort location: cytoplasmic, score: 23; hypothetical protein 1451992..1453242 Cronobacter sakazakii ATCC BAA-894 5549907 YP_001437605.1 CDS ESA_01511 NC_009778.1 1453252 1454133 D KEGG: rha:RHA1_ro08170 7.5e-24 ABC transporter, permease component; COG: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1453252..1454133 Cronobacter sakazakii ATCC BAA-894 5549731 YP_001437606.1 CDS ESA_01512 NC_009778.1 1454143 1454931 D KEGG: azo:azo0944 1.1e-86 nasD; putative nitrate transport system, ATP-binding protein; COG: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 1454143..1454931 Cronobacter sakazakii ATCC BAA-894 5549724 YP_001437607.1 CDS ESA_01513 NC_009778.1 1454941 1459008 D KEGG: eca:ECA2991 0. nasB; nitrite reductase [NAD(P)H] large subunit K00362; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: mitochondrial, score: 23; hypothetical protein 1454941..1459008 Cronobacter sakazakii ATCC BAA-894 5549649 YP_001437608.1 CDS ESA_01514 NC_009778.1 1459005 1461707 D KEGG: eca:ECA2990 8.0e-281 nasA; nitrate reductase K00372; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: cytoplasmic, score: 23; hypothetical protein 1459005..1461707 Cronobacter sakazakii ATCC BAA-894 5549569 YP_001437609.1 CDS ESA_01515 NC_009778.1 1461603 1462154 R COG: COG1881 Phospholipid-binding protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1461603..1462154) Cronobacter sakazakii ATCC BAA-894 5549886 YP_001437610.1 CDS ESA_01516 NC_009778.1 1462332 1463747 D COG: NOG06760 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1462332..1463747 Cronobacter sakazakii ATCC BAA-894 5550094 YP_001437611.1 CDS ESA_01517 NC_009778.1 1463744 1464394 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1463744..1464394) Cronobacter sakazakii ATCC BAA-894 5549962 YP_001437612.1 CDS ESA_01518 NC_009778.1 1464387 1466195 R KEGG: ecp:ECP_1271 1.9e-224 nitrate/nitrite sensor protein NarX K07673; COG: COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific; Psort location: endoplasmic reticulum, score: 9; nitrate/nitrite sensor protein NarX complement(1464387..1466195) Cronobacter sakazakii ATCC BAA-894 5549884 YP_001437613.1 CDS ESA_01519 NC_009778.1 1466493 1467899 D COG: COG2223 Nitrate/nitrite transporter; Psort location: plasma membrane, score: 23; hypothetical protein 1466493..1467899 Cronobacter sakazakii ATCC BAA-894 5550025 YP_001437614.1 CDS ESA_01520 NC_009778.1 1468317 1472063 D KEGG: stm:STM1764 0. narG; nitrate reductase alpha chain K00370; COG: COG5013 Nitrate reductase alpha subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 1468317..1472063 Cronobacter sakazakii ATCC BAA-894 5551367 YP_001437615.1 CDS ESA_01521 NC_009778.1 1472060 1473595 D KEGG: stt:t1672 5.6e-273 narH; respiratory nitrate reductase 1 beta chain K00371; COG: COG1140 Nitrate reductase beta subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 1472060..1473595 Cronobacter sakazakii ATCC BAA-894 5549966 YP_001437616.1 CDS ESA_01522 NC_009778.1 1473592 1474302 D KEGG: stm:STM1762 1.3e-97 narJ; nitrate reductase delta chain K00373; COG: COG2180 Nitrate reductase delta subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 1473592..1474302 Cronobacter sakazakii ATCC BAA-894 5549945 YP_001437617.1 CDS ESA_01523 NC_009778.1 1474302 1474979 D KEGG: stm:STM1761 2.8e-104 narI; nitrate reductase gamma chain K00374; COG: COG2181 Nitrate reductase gamma subunit; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1474302..1474979 Cronobacter sakazakii ATCC BAA-894 5549984 YP_001437618.1 CDS ESA_01524 NC_009778.1 1475125 1476069 R KEGG: xac:XAC2822 1.1e-05 Ada, AlkA; DNA methylation and regulatory protein K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1475125..1476069) Cronobacter sakazakii ATCC BAA-894 5550103 YP_001437619.1 CDS ESA_01525 NC_009778.1 1476164 1476934 D KEGG: bur:Bcep18194_B0662 7.3e-65 short-chain dehydrogenase/reductase SDR K00044; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 1476164..1476934 Cronobacter sakazakii ATCC BAA-894 5550160 YP_001437620.1 CDS purU NC_009778.1 1477841 1478683 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1477841..1478683) Cronobacter sakazakii ATCC BAA-894 5549523 YP_001437621.1 CDS ESA_01531 NC_009778.1 1478734 1479066 R KEGG: pen:PSEEN4477 0.00064 secA; preprotein translocase SecA subunit; COG: COG3012 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1478734..1479066) Cronobacter sakazakii ATCC BAA-894 5549370 YP_001437622.1 CDS ESA_01532 NC_009778.1 1479547 1480560 D KEGG: eci:UTI89_C1431 1.4e-148 rssB; RssB/Hnr protein K02485; COG: COG0784 FOG: CheY-like receiver; Psort location: cytoplasmic, score: 23; response regulator of RpoS 1479547..1480560 Cronobacter sakazakii ATCC BAA-894 5549319 YP_001437623.1 CDS ESA_01533 NC_009778.1 1480762 1481670 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1480762..1481670 Cronobacter sakazakii ATCC BAA-894 5550211 YP_001437624.1 CDS ESA_01534 NC_009778.1 1481692 1483032 D KEGG: sgl:SG1368 7.6e-205 putative UDP-glucose dehydrogenase K00012; COG: COG1004 Predicted UDP-glucose 6-dehydrogenase; Psort location: extracellular, including cell wall, score: 23; hypothetical protein 1481692..1483032 Cronobacter sakazakii ATCC BAA-894 5550168 YP_001437625.1 CDS ESA_01536 NC_009778.1 1482993 1483121 R Psort location: nuclear, score: 23; hypothetical protein complement(1482993..1483121) Cronobacter sakazakii ATCC BAA-894 5549583 YP_001437626.1 CDS ESA_01535 NC_009778.1 1483047 1484060 D KEGG: sgl:SG1369 6.2e-139 putative nucleotide sugar epimerase; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein 1483047..1484060 Cronobacter sakazakii ATCC BAA-894 5549557 YP_001437627.1 CDS ESA_01537 NC_009778.1 1484175 1484588 R COG: COG2916 DNA-binding protein H-NS; Psort location: nuclear, score: 23; global DNA-binding transcriptional dual regulator H-NS complement(1484175..1484588) Cronobacter sakazakii ATCC BAA-894 5549603 YP_001437628.1 CDS ESA_01538 NC_009778.1 1485130 1485735 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1485130..1485735 Cronobacter sakazakii ATCC BAA-894 5549478 YP_001437629.1 CDS ESA_01539 NC_009778.1 1486093 1488771 R KEGG: sbo:SBO_1828 0. adhE; CoA-linked acetaldehyde dehydrogenase/iron-dependent alcohol dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: cytoplasmic, score: 23; bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1486093..1488771) Cronobacter sakazakii ATCC BAA-894 5549503 YP_001437630.1 CDS ESA_01540 NC_009778.1 1489251 1489889 D COG: COG2095 Multiple antibiotic transporter; Psort location: plasma membrane, score: 23; hypothetical protein 1489251..1489889 Cronobacter sakazakii ATCC BAA-894 5550157 YP_001437631.1 CDS ESA_01541 NC_009778.1 1490680 1492308 D KEGG: shn:Shewana3_2650 4.1e-20 acetate kinase K00925; COG: COG4166 ABC-type oligopeptide transport system, periplasmic component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1490680..1492308 Cronobacter sakazakii ATCC BAA-894 5549839 YP_001437632.1 CDS oppB NC_009778.1 1492392 1493312 D KEGG: rha:RHA1_ro09047 1.5e-43 ABC peptide transporter, permease component K02033; COG: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; oligopeptide transporter permease 1492392..1493312 Cronobacter sakazakii ATCC BAA-894 5550024 YP_001437633.1 CDS ESA_01543 NC_009778.1 1493327 1494235 D KEGG: baa:BA_0884 0.0024 binding-protein-dependent transport systems inner membrane component K00294; COG: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1493327..1494235 Cronobacter sakazakii ATCC BAA-894 5549861 YP_001437634.1 CDS oppD NC_009778.1 1494247 1495260 D KEGG: rru:Rru_A0589 1.9e-96 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like K02031; COG: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Psort location: cytoplasmic, score: 23; oligopeptide transporter ATP-binding component 1494247..1495260 Cronobacter sakazakii ATCC BAA-894 5549806 YP_001437635.1 CDS ESA_01545 NC_009778.1 1495257 1496261 D KEGG: bur:Bcep18194_B0119 4.2e-94 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032; COG: COG4608 ABC-type oligopeptide transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 1495257..1496261 Cronobacter sakazakii ATCC BAA-894 5549870 YP_001437636.1 CDS ESA_01546 NC_009778.1 1496278 1497144 D COG: COG1226 Kef-type K+ transport systems, predicted NAD-binding component; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1496278..1497144 Cronobacter sakazakii ATCC BAA-894 5549776 YP_001437637.1 CDS ESA_01547 NC_009778.1 1497174 1497503 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1497174..1497503) Cronobacter sakazakii ATCC BAA-894 5549729 YP_001437638.1 CDS cls NC_009778.1 1497538 1498998 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1497538..1498998) Cronobacter sakazakii ATCC BAA-894 5549692 YP_001437639.1 CDS ESA_01549 NC_009778.1 1500169 1500465 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(1500169..1500465) Cronobacter sakazakii ATCC BAA-894 5549268 YP_001437640.1 CDS ESA_01550 NC_009778.1 1500689 1501414 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1500689..1501414 Cronobacter sakazakii ATCC BAA-894 5552341 YP_001437641.1 CDS ESA_01551 NC_009778.1 1501465 1501866 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1501465..1501866) Cronobacter sakazakii ATCC BAA-894 5550296 YP_001437642.1 CDS ESA_01552 NC_009778.1 1502028 1504217 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(1502028..1504217) Cronobacter sakazakii ATCC BAA-894 5549546 YP_001437643.1 CDS ESA_01553 NC_009778.1 1504449 1504985 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1504449..1504985) Cronobacter sakazakii ATCC BAA-894 5549576 YP_001437644.1 CDS ESA_01554 NC_009778.1 1505037 1505780 R COG: NOG06197 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1505037..1505780) Cronobacter sakazakii ATCC BAA-894 5549567 YP_001437645.1 CDS ESA_01555 NC_009778.1 1505805 1506215 R COG: COG0727 Predicted Fe-S-cluster oxidoreductase; Psort location: nuclear, score: 23; hypothetical protein complement(1505805..1506215) Cronobacter sakazakii ATCC BAA-894 5550215 YP_001437646.1 CDS ESA_01556 NC_009778.1 1506495 1507127 D receptor for colicin S4; outer membrane protein W 1506495..1507127 Cronobacter sakazakii ATCC BAA-894 5550170 YP_001437647.1 CDS ESA_01557 NC_009778.1 1507258 1507398 R Psort location: nuclear, score: 23; hypothetical protein complement(1507258..1507398) Cronobacter sakazakii ATCC BAA-894 5550255 YP_001437648.1 CDS ESA_01558 NC_009778.1 1507776 1508585 R KEGG: sfx:S1349 1.3e-113 trpA; tryptophan synthase, alpha protein K01695; COG: COG0159 Tryptophan synthase alpha chain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1507776..1508585) Cronobacter sakazakii ATCC BAA-894 5550216 YP_001437649.1 CDS ESA_01559 NC_009778.1 1508585 1509778 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1508585..1509778) Cronobacter sakazakii ATCC BAA-894 5549580 YP_001437650.1 CDS ESA_01560 NC_009778.1 1509791 1511149 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1509791..1511149) Cronobacter sakazakii ATCC BAA-894 5549534 YP_001437651.1 CDS ESA_01561 NC_009778.1 1511153 1512748 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1511153..1512748) Cronobacter sakazakii ATCC BAA-894 5549617 YP_001437652.1 CDS ESA_01562 NC_009778.1 1512748 1514382 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1512748..1514382) Cronobacter sakazakii ATCC BAA-894 5552481 YP_001437653.1 CDS ESA_01563 NC_009778.1 1514588 1515466 D KEGG: reh:H16_A1200 7.1e-51 predicted metal-dependent phosphoesterase (PHP family); COG: COG0613 Predicted metal-dependent phosphoesterases (PHP family); Psort location: cytoplasmic, score: 23; hypothetical protein 1514588..1515466 Cronobacter sakazakii ATCC BAA-894 5552424 YP_001437654.1 CDS ESA_01564 NC_009778.1 1515533 1516084 D COG: COG0009 Putative translation factor (SUA5); Psort location: cytoplasmic, score: 23; hypothetical protein 1515533..1516084 Cronobacter sakazakii ATCC BAA-894 5549517 YP_001437655.1 CDS ESA_01565 NC_009778.1 1516211 1517296 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1516211..1517296 Cronobacter sakazakii ATCC BAA-894 5549518 YP_001437656.1 CDS ESA_01566 NC_009778.1 1517351 1517941 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1517351..1517941) Cronobacter sakazakii ATCC BAA-894 5549555 YP_001437657.1 CDS ESA_01567 NC_009778.1 1517938 1518699 R KEGG: eco:b1271 1.9e-105 yciK; short chain dehydrogenase K00100; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; short chain dehydrogenase complement(1517938..1518699) Cronobacter sakazakii ATCC BAA-894 5549683 YP_001437658.1 CDS ESA_01568 NC_009778.1 1518958 1520007 D SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1518958..1520007 Cronobacter sakazakii ATCC BAA-894 5550013 YP_001437659.1 CDS ESA_01569 NC_009778.1 1520062 1520325 D Psort location: cytoplasmic, score: 23; hypothetical protein 1520062..1520325 Cronobacter sakazakii ATCC BAA-894 5550054 YP_001437660.1 CDS ESA_01570 NC_009778.1 1520083 1520340 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1520083..1520340) Cronobacter sakazakii ATCC BAA-894 5549854 YP_001437661.1 CDS ESA_01571 NC_009778.1 1520735 1523332 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1520735..1523332 Cronobacter sakazakii ATCC BAA-894 5549851 YP_001437662.1 CDS cysB NC_009778.1 1523520 1524494 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1523520..1524494 Cronobacter sakazakii ATCC BAA-894 5549682 YP_001437663.1 CDS ESA_01573 NC_009778.1 1525282 1525407 D Psort location: cytoplasmic, score: 23; hypothetical protein 1525282..1525407 Cronobacter sakazakii ATCC BAA-894 5549782 YP_001437664.1 CDS ESA_01574 NC_009778.1 1525576 1528251 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1525576..1528251 Cronobacter sakazakii ATCC BAA-894 5550086 YP_001437665.1 CDS ribA NC_009778.1 1528315 1528908 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1528315..1528908) Cronobacter sakazakii ATCC BAA-894 5550204 YP_001437666.1 CDS ESA_01576 NC_009778.1 1529108 1529872 D KEGG: spt:SPA1166 2.6e-108 pgpB; phosphatidylglycerophosphatase B K01096; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: endoplasmic reticulum, score: 9; phosphatidylglycerophosphatase B 1529108..1529872 Cronobacter sakazakii ATCC BAA-894 5550178 YP_001437667.1 CDS ESA_01577 NC_009778.1 1530020 1530328 D COG: COG3771 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1530020..1530328 Cronobacter sakazakii ATCC BAA-894 5552279 YP_001437668.1 CDS ESA_01578 NC_009778.1 1530335 1531504 D KEGG: azo:azo1075 2.6e-60 conserved hypothetical transferase protein; COG: COG2956 Predicted N-acetylglucosaminyl transferase; Psort location: cytoplasmic, score: 23; tetratricopeptide repeat protein 1530335..1531504 Cronobacter sakazakii ATCC BAA-894 5550229 YP_001437669.1 CDS ESA_01579 NC_009778.1 1531673 1532464 D KEGG: spt:SPA1169 3.2e-103 pyrF; orotidine-5'-P decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: cytoplasmic, score: 23; hypothetical protein 1531673..1532464 Cronobacter sakazakii ATCC BAA-894 5549651 YP_001437670.1 CDS ESA_01580 NC_009778.1 1532464 1532790 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1532464..1532790 Cronobacter sakazakii ATCC BAA-894 5549638 YP_001437671.1 CDS ESA_01581 NC_009778.1 1532912 1533127 R COG: NOG17005 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1532912..1533127) Cronobacter sakazakii ATCC BAA-894 5549545 YP_001437672.1 CDS ESA_01582 NC_009778.1 1533385 1534185 R COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1533385..1534185) Cronobacter sakazakii ATCC BAA-894 5549476 YP_001437673.1 CDS ESA_01583 NC_009778.1 1534186 1536639 R KEGG: sec:SC0838 0. pflF; putative pyruvate formate lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1534186..1536639) Cronobacter sakazakii ATCC BAA-894 5552445 YP_001437674.1 CDS ESA_01584 NC_009778.1 1536624 1537532 R KEGG: ecj:JW0808 9.4e-120 ybiY; predicted pyruvate formate lyase activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1536624..1537532) Cronobacter sakazakii ATCC BAA-894 5549463 YP_001437675.1 CDS ESA_01585 NC_009778.1 1537660 1538322 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 1537660..1538322 Cronobacter sakazakii ATCC BAA-894 5549543 YP_001437676.1 CDS ESA_01586 NC_009778.1 1538336 1538518 R COG: NOG34196 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1538336..1538518) Cronobacter sakazakii ATCC BAA-894 5549502 YP_001437677.1 CDS ESA_01587 NC_009778.1 1538730 1539599 D regulator of pathogenicity factor RpfF; involved in synthesis of a diffusible signal factor involved in the regulation of extracellular enzymes; enoyl-CoA hydratase 1538730..1539599 Cronobacter sakazakii ATCC BAA-894 5549550 YP_001437678.1 CDS ESA_01588 NC_009778.1 1539621 1541615 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1539621..1541615) Cronobacter sakazakii ATCC BAA-894 5552468 YP_001437679.1 CDS ESA_01589 NC_009778.1 1541912 1543846 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1541912..1543846) Cronobacter sakazakii ATCC BAA-894 5549705 YP_001437680.1 CDS ESA_01590 NC_009778.1 1543934 1545088 R COG: COG2128 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1543934..1545088) Cronobacter sakazakii ATCC BAA-894 5549515 YP_001437681.1 CDS ESA_01591 NC_009778.1 1545278 1546066 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(1545278..1546066) Cronobacter sakazakii ATCC BAA-894 5549537 YP_001437682.1 CDS ESA_01592 NC_009778.1 1546187 1546993 R KEGG: bur:Bcep18194_A6388 1.8e-52 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032; COG: COG4167 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1546187..1546993) Cronobacter sakazakii ATCC BAA-894 5550283 YP_001437683.1 CDS ESA_01593 NC_009778.1 1546995 1547987 R KEGG: ret:RHE_CH00739 9.1e-67 dppDch1, dppFch1; dipeptide ABC transporter, ATP-binding protein K02031; COG: COG4170 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: nuclear, score: 23; hypothetical protein complement(1546995..1547987) Cronobacter sakazakii ATCC BAA-894 5550163 YP_001437684.1 CDS ESA_01594 NC_009778.1 1547987 1548877 R KEGG: lwe:lwe0999 0.0031 gbuB; glycine betaine/L-proline ABC transporter, permease protein; COG: COG4171 ABC-type antimicrobial peptide transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1547987..1548877) Cronobacter sakazakii ATCC BAA-894 5550182 YP_001437685.1 CDS ESA_01595 NC_009778.1 1548864 1549829 R KEGG: syf:Synpcc7942_2454 5.5e-28 adenine phosphoribosyltransferase K00759; COG: COG4168 ABC-type antimicrobial peptide transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1548864..1549829) Cronobacter sakazakii ATCC BAA-894 5552387 YP_001437686.1 CDS ESA_01596 NC_009778.1 1549826 1551466 R KEGG: shn:Shewana3_2650 1.3e-123 acetate kinase K00925; COG: COG4166 ABC-type oligopeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1549826..1551466) Cronobacter sakazakii ATCC BAA-894 5550162 YP_001437687.1 CDS pspF NC_009778.1 1551564 1552550 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1551564..1552550) Cronobacter sakazakii ATCC BAA-894 5549452 YP_001437688.1 CDS ESA_01598 NC_009778.1 1552718 1553389 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1552718..1553389 Cronobacter sakazakii ATCC BAA-894 5549585 YP_001437689.1 CDS pspB NC_009778.1 1553455 1553679 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1553455..1553679 Cronobacter sakazakii ATCC BAA-894 5550250 YP_001437690.1 CDS ESA_01600 NC_009778.1 1553679 1554035 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1553679..1554035 Cronobacter sakazakii ATCC BAA-894 5550267 YP_001437691.1 CDS ESA_01601 NC_009778.1 1554081 1554320 D COG: NOG14121 non supervised orthologous group; Psort location: mitochondrial, score: 23; peripheral inner membrane phage-shock protein 1554081..1554320 Cronobacter sakazakii ATCC BAA-894 5550276 YP_001437692.1 CDS ESA_01602 NC_009778.1 1554480 1556210 D KEGG: ece:Z2475m 4.9e-194 glycosidase K00690; COG: COG0366 Glycosidases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1554480..1556210 Cronobacter sakazakii ATCC BAA-894 5552152 YP_001437693.1 CDS ESA_01603 NC_009778.1 1556222 1557514 D KEGG: eci:UTI89_C1581 5.2e-167 ycjN; putative ABC transporter periplasmic binding protein YcjN precursor K02027; COG: COG1653 ABC-type sugar transport system, periplasmic component; Psort location: mitochondrial, score: 23; hypothetical protein 1556222..1557514 Cronobacter sakazakii ATCC BAA-894 5552171 YP_001437694.1 CDS ESA_01604 NC_009778.1 1557529 1558419 D KEGG: tel:tlr1429 0.00010 ndhC; NADH dehydrogenase subunit 3 K05574; COG: COG1175 ABC-type sugar transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1557529..1558419 Cronobacter sakazakii ATCC BAA-894 5552153 YP_001437695.1 CDS ESA_01605 NC_009778.1 1558406 1559248 D KEGG: cyb:CYB_0398 0.0069 modB; molybdate ABC transporter, permease protein K02018; COG: COG0395 ABC-type sugar transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1558406..1559248 Cronobacter sakazakii ATCC BAA-894 5552165 YP_001437696.1 CDS ESA_01606 NC_009778.1 1559274 1560323 D KEGG: hwa:HQ2425A 1.2e-20 tdh; oxidoreductase (probable Zn-dependent dehydrogenases, threonine 3-dehydrogenase) K00060; COG: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1559274..1560323 Cronobacter sakazakii ATCC BAA-894 5552133 YP_001437697.1 CDS ESA_01607 NC_009778.1 1560342 1560998 D KEGG: eci:UTI89_C1585 1.7e-97 ycjR; putative transient receptor potential locus K01820; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein 1560342..1560998 Cronobacter sakazakii ATCC BAA-894 5552139 YP_001437698.1 CDS ESA_01608 NC_009778.1 1561010 1562293 R COG: COG0582 Integrase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1561010..1562293) Cronobacter sakazakii ATCC BAA-894 5552119 YP_001437699.1 CDS ESA_01609 NC_009778.1 1562319 1562609 R COG: NOG18529 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1562319..1562609) Cronobacter sakazakii ATCC BAA-894 5552104 YP_001437700.1 CDS ESA_01610 NC_009778.1 1562651 1563751 R COG: NOG23864 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1562651..1563751) Cronobacter sakazakii ATCC BAA-894 5552082 YP_001437701.1 CDS ESA_01611 NC_009778.1 1563753 1564028 R COG: NOG14124 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1563753..1564028) Cronobacter sakazakii ATCC BAA-894 5552045 YP_001437702.1 CDS ESA_01612 NC_009778.1 1564736 1565341 R COG: COG2932 Predicted transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1564736..1565341) Cronobacter sakazakii ATCC BAA-894 5552046 YP_001437703.1 CDS ESA_01613 NC_009778.1 1565729 1566073 D Psort location: mitochondrial, score: 23; hypothetical protein 1565729..1566073 Cronobacter sakazakii ATCC BAA-894 5552088 YP_001437704.1 CDS ESA_01614 NC_009778.1 1566164 1567021 D COG: NOG14675 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 1566164..1567021 Cronobacter sakazakii ATCC BAA-894 5552068 YP_001437705.1 CDS ESA_01615 NC_009778.1 1567018 1567764 D COG: NOG20728 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 1567018..1567764 Cronobacter sakazakii ATCC BAA-894 5552064 YP_001437706.1 CDS ESA_01616 NC_009778.1 1568025 1569134 D KEGG: sto:ST0842 6.4e-05 hypothetical ABC transporter ATP-binding protein K02013; COG: COG1106 Predicted ATPases; Psort location: nuclear, score: 23; hypothetical protein 1568025..1569134 Cronobacter sakazakii ATCC BAA-894 5552077 YP_001437707.1 CDS ESA_01617 NC_009778.1 1569134 1569793 D Psort location: cytoplasmic, score: 23; hypothetical protein 1569134..1569793 Cronobacter sakazakii ATCC BAA-894 5552027 YP_001437708.1 CDS ESA_01618 NC_009778.1 1570798 1571253 D DLP12 prophage; hypothetical protein 1570798..1571253 Cronobacter sakazakii ATCC BAA-894 5552051 YP_001437709.1 CDS ESA_01619 NC_009778.1 1571262 1571456 D COG: NOG32342 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 1571262..1571456 Cronobacter sakazakii ATCC BAA-894 5552020 YP_001437710.1 CDS ESA_01620 NC_009778.1 1571447 1571743 D Psort location: cytoplasmic, score: 23; hypothetical protein 1571447..1571743 Cronobacter sakazakii ATCC BAA-894 5552030 YP_001437711.1 CDS ESA_01621 NC_009778.1 1571740 1572102 D KEGG: eci:UTI89_C1478 6.3e-27 endodeoxyribonuclease RusA (Holliday junction resolvase) K01160; COG: COG4570 Holliday junction resolvase; Psort location: cytoplasmic, score: 23; hypothetical protein 1571740..1572102 Cronobacter sakazakii ATCC BAA-894 5552039 YP_001437712.1 CDS ESA_01622 NC_009778.1 1572099 1572794 D COG: NOG18124 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1572099..1572794 Cronobacter sakazakii ATCC BAA-894 5552029 YP_001437713.1 CDS ESA_01623 NC_009778.1 1572928 1573161 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1572928..1573161 Cronobacter sakazakii ATCC BAA-894 5551954 YP_001437714.1 CDS ESA_01624 NC_009778.1 1573909 1574124 D COG: NOG20218 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1573909..1574124 Cronobacter sakazakii ATCC BAA-894 5551994 YP_001437715.1 CDS ESA_01625 NC_009778.1 1574121 1574609 D KEGG: ecs:ECs0819 3.0e-52 probable endolysin (lysis protein) (lysozyme) K01185; COG: COG3772 Phage-related lysozyme (muraminidase); Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1574121..1574609 Cronobacter sakazakii ATCC BAA-894 5552003 YP_001437716.1 CDS ESA_01626 NC_009778.1 1574609 1574959 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1574609..1574959 Cronobacter sakazakii ATCC BAA-894 5552000 YP_001437717.1 CDS ESA_01627 NC_009778.1 1575497 1575748 D Psort location: cytoskeletal, score: 9; hypothetical protein 1575497..1575748 Cronobacter sakazakii ATCC BAA-894 5551980 YP_001437718.1 CDS ESA_01628 NC_009778.1 1575755 1576156 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1575755..1576156) Cronobacter sakazakii ATCC BAA-894 5551894 YP_001437719.1 CDS ESA_01629 NC_009778.1 1576631 1576951 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1576631..1576951) Cronobacter sakazakii ATCC BAA-894 5551820 YP_001437720.1 CDS ESA_01630 NC_009778.1 1576976 1577239 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1576976..1577239) Cronobacter sakazakii ATCC BAA-894 5551958 YP_001437721.1 CDS ESA_01631 NC_009778.1 1577833 1578021 D Psort location: cytoplasmic, score: 23; hypothetical protein 1577833..1578021 Cronobacter sakazakii ATCC BAA-894 5551922 YP_001437722.1 CDS ESA_01632 NC_009778.1 1578481 1578813 D COG: COG3747 Phage terminase, small subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 1578481..1578813 Cronobacter sakazakii ATCC BAA-894 5551921 YP_001437723.1 CDS ESA_01633 NC_009778.1 1578817 1580544 D COG: COG4626 Phage terminase-like protein, large subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 1578817..1580544 Cronobacter sakazakii ATCC BAA-894 5551911 YP_001437724.1 CDS ESA_01634 NC_009778.1 1580541 1580690 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1580541..1580690 Cronobacter sakazakii ATCC BAA-894 5550309 YP_001437725.1 CDS ESA_01635 NC_009778.1 1580690 1581931 D COG: COG4695 Phage-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1580690..1581931 Cronobacter sakazakii ATCC BAA-894 5551891 YP_001437726.1 CDS ESA_01636 NC_009778.1 1581924 1582547 D KEGG: mtu:Rv2651c 0.0082 possible phiRv2 prophage protease; COG: COG3740 Phage head maturation protease; Psort location: cytoplasmic, score: 23; hypothetical protein 1581924..1582547 Cronobacter sakazakii ATCC BAA-894 5551918 YP_001437727.1 CDS ESA_01637 NC_009778.1 1582617 1583837 D COG: COG4653 Predicted phage phi-C31 gp36 major capsid-like protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1582617..1583837 Cronobacter sakazakii ATCC BAA-894 5551878 YP_001437728.1 CDS ESA_01638 NC_009778.1 1583843 1584109 D KEGG: pat:Patl_2341 2.1e-05 agarase K01219; COG: COG5492 Bacterial surface proteins containing Ig-like domains; Psort location: cytoplasmic, score: 23; hypothetical protein 1583843..1584109 Cronobacter sakazakii ATCC BAA-894 5551893 YP_001437729.1 CDS ESA_01639 NC_009778.1 1584144 1584461 D COG: NOG24115 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1584144..1584461 Cronobacter sakazakii ATCC BAA-894 5551892 YP_001437730.1 CDS ESA_01640 NC_009778.1 1584458 1584853 D COG: NOG32857 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 1584458..1584853 Cronobacter sakazakii ATCC BAA-894 5550244 YP_001437731.1 CDS ESA_01641 NC_009778.1 1584846 1585364 D COG: NOG30834 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 1584846..1585364 Cronobacter sakazakii ATCC BAA-894 5551886 YP_001437732.1 CDS ESA_01642 NC_009778.1 1585361 1585870 D COG: NOG22114 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1585361..1585870 Cronobacter sakazakii ATCC BAA-894 5552175 YP_001437733.1 CDS ESA_01643 NC_009778.1 1585861 1586433 D COG: COG3778 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1585861..1586433 Cronobacter sakazakii ATCC BAA-894 5551901 YP_001437734.1 CDS ESA_01644 NC_009778.1 1586491 1587672 D COG: COG5301 Phage-related tail fibre protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1586491..1587672 Cronobacter sakazakii ATCC BAA-894 5551874 YP_001437735.1 CDS ESA_01645 NC_009778.1 1588270 1588557 D Psort location: mitochondrial, score: 23; hypothetical protein 1588270..1588557 Cronobacter sakazakii ATCC BAA-894 5550237 YP_001437736.1 CDS ESA_01646 NC_009778.1 1589424 1589924 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1589424..1589924) Cronobacter sakazakii ATCC BAA-894 5551884 YP_001437737.1 CDS ESA_01647 NC_009778.1 1589928 1590716 D KEGG: ecc:c1787 9.2e-106 ycjS; hypothetical oxidoreductase YcjS; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 1589928..1590716 Cronobacter sakazakii ATCC BAA-894 5551879 YP_001437738.1 CDS ESA_01648 NC_009778.1 1590713 1592947 D KEGG: eci:UTI89_C1587 2.3e-244 ycjT; hypothetical transport protein YcjT; COG: COG1554 Trehalose and maltose hydrolases (possible phosphorylases); Psort location: cytoplasmic, score: 23; hypothetical protein 1590713..1592947 Cronobacter sakazakii ATCC BAA-894 5551860 YP_001437739.1 CDS ESA_01649 NC_009778.1 1592944 1593621 D KEGG: eco:b1317 6.5e-73 ycjU, pgmB; putative beta phosphoglucomutase, contains a phophatase-like domain K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1592944..1593621 Cronobacter sakazakii ATCC BAA-894 5552026 YP_001437740.1 CDS ESA_01650 NC_009778.1 1593637 1594719 D KEGG: sth:STH1782 9.8e-102 sugar ABC transportor ATP-binding protein K05816; COG: COG3839 ABC-type sugar transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein 1593637..1594719 Cronobacter sakazakii ATCC BAA-894 5551830 YP_001437741.1 CDS ESA_01651 NC_009778.1 1594769 1595776 R KEGG: efa:EF1922 6.3e-09 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1594769..1595776) Cronobacter sakazakii ATCC BAA-894 5551867 YP_001437742.1 CDS ESA_01652 NC_009778.1 1595924 1597324 D KEGG: sdy:SDY_1399 3.6e-214 ycjX; putative YcjX; COG: COG3106 Predicted ATPase; Psort location: cytoplasmic, score: 23; hypothetical protein 1595924..1597324 Cronobacter sakazakii ATCC BAA-894 5551821 YP_001437743.1 CDS ESA_01653 NC_009778.1 1597321 1598364 D COG: COG3768 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1597321..1598364 Cronobacter sakazakii ATCC BAA-894 5551790 YP_001437744.1 CDS ESA_01654 NC_009778.1 1598495 1600075 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1598495..1600075 Cronobacter sakazakii ATCC BAA-894 5551858 YP_001437745.1 CDS tpx NC_009778.1 1600127 1600633 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1600127..1600633) Cronobacter sakazakii ATCC BAA-894 5551827 YP_001437746.1 CDS ESA_01656 NC_009778.1 1600770 1601768 D KEGG: sfl:SF1331 2.1e-131 ycjG; putative muconate cycloisomerase I; COG: COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein 1600770..1601768 Cronobacter sakazakii ATCC BAA-894 5551818 YP_001437747.1 CDS ESA_01657 NC_009778.1 1601750 1602472 R KEGG: gka:GK2441 0.0034 gamma-D-glutamyl-L-diamino acid endopeptidase I (endopeptidase I) K01308; COG: COG2866 Predicted carboxypeptidase; Psort location: cytoplasmic, score: 23; murein peptide amidase A complement(1601750..1602472) Cronobacter sakazakii ATCC BAA-894 5551846 YP_001437748.1 CDS ESA_01658 NC_009778.1 1602717 1604333 D KEGG: shn:Shewana3_2650 2.8e-22 acetate kinase K00925; COG: COG4166 ABC-type oligopeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1602717..1604333 Cronobacter sakazakii ATCC BAA-894 5551775 YP_001437749.1 CDS ESA_01659 NC_009778.1 1604394 1604834 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1604394..1604834) Cronobacter sakazakii ATCC BAA-894 5551831 YP_001437750.1 CDS ESA_01660 NC_009778.1 1604952 1605299 R COG: NOG12165 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1604952..1605299) Cronobacter sakazakii ATCC BAA-894 5552083 YP_001437751.1 CDS ESA_01661 NC_009778.1 1605774 1606355 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1605774..1606355) Cronobacter sakazakii ATCC BAA-894 5551812 YP_001437752.1 CDS ESA_01662 NC_009778.1 1606596 1606850 D Psort location: cytoplasmic, score: 23; hypothetical protein 1606596..1606850 Cronobacter sakazakii ATCC BAA-894 5552044 YP_001437753.1 CDS ESA_01663 NC_009778.1 1606868 1607215 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1606868..1607215 Cronobacter sakazakii ATCC BAA-894 5551793 YP_001437754.1 CDS ESA_01664 NC_009778.1 1606942 1607223 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1606942..1607223) Cronobacter sakazakii ATCC BAA-894 5551729 YP_001437755.1 CDS ESA_01665 NC_009778.1 1607711 1607839 R Psort location: nuclear, score: 23; hypothetical protein complement(1607711..1607839) Cronobacter sakazakii ATCC BAA-894 5551799 YP_001437756.1 CDS ESA_01666 NC_009778.1 1607959 1609710 R KEGG: shn:Shewana3_3829 3.6e-41 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1607959..1609710) Cronobacter sakazakii ATCC BAA-894 5551747 YP_001437757.1 CDS ESA_01667 NC_009778.1 1609849 1610121 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1609849..1610121) Cronobacter sakazakii ATCC BAA-894 5552235 YP_001437758.1 CDS ESA_01668 NC_009778.1 1610176 1610448 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1610176..1610448) Cronobacter sakazakii ATCC BAA-894 5551787 YP_001437759.1 CDS ESA_01669 NC_009778.1 1610701 1610874 D COG: NOG12162 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1610701..1610874 Cronobacter sakazakii ATCC BAA-894 5551754 YP_001437760.1 CDS ESA_01671 NC_009778.1 1610938 1611162 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1610938..1611162) Cronobacter sakazakii ATCC BAA-894 5551735 YP_001437761.1 CDS ESA_01670 NC_009778.1 1610953 1611156 D Psort location: nuclear, score: 23; hypothetical protein 1610953..1611156 Cronobacter sakazakii ATCC BAA-894 5551762 YP_001437762.1 CDS zntB NC_009778.1 1611196 1612179 D COG: COG0598 Mg2+ and Co2+ transporters; Psort location: cytoplasmic, score: 23; zinc transporter 1611196..1612179 Cronobacter sakazakii ATCC BAA-894 5551774 YP_001437763.1 CDS ESA_01673 NC_009778.1 1612499 1612648 D COG: COG3468 Type V secretory pathway, adhesin AidA; Psort location: nuclear, score: 23; hypothetical protein 1612499..1612648 Cronobacter sakazakii ATCC BAA-894 5551770 YP_001437764.1 CDS ESA_01675 NC_009778.1 1612686 1613618 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1612686..1613618) Cronobacter sakazakii ATCC BAA-894 5551751 YP_001437765.1 CDS ESA_01674 NC_009778.1 1613604 1613816 D Psort location: mitochondrial, score: 23; hypothetical protein 1613604..1613816 Cronobacter sakazakii ATCC BAA-894 5551953 YP_001437766.1 CDS ESA_01676 NC_009778.1 1613904 1615016 D COG: NOG16515 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1613904..1615016 Cronobacter sakazakii ATCC BAA-894 5551759 YP_001437767.1 CDS ESA_01677 NC_009778.1 1615221 1615385 D Psort location: mitochondrial, score: 23; hypothetical protein 1615221..1615385 Cronobacter sakazakii ATCC BAA-894 5551720 YP_001437768.1 CDS ESA_01678 NC_009778.1 1615486 1616277 D KEGG: bxe:Bxe_B1317 1.1e-102 short-chain dehydrogenase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 1615486..1616277 Cronobacter sakazakii ATCC BAA-894 5551704 YP_001437769.1 CDS ESA_01679 NC_009778.1 1616295 1617365 D KEGG: stl:stu1732 1.5e-34 pmi1; mannose-6-phosphate isomerase K01809; COG: COG1482 Phosphomannose isomerase; Psort location: cytoplasmic, score: 23; hypothetical protein 1616295..1617365 Cronobacter sakazakii ATCC BAA-894 5551689 YP_001437770.1 CDS ESA_01680 NC_009778.1 1617346 1619151 R KEGG: reh:H16_B1962 6.3e-91 transcriptional regulator, PspF-family K01529; COG: COG3284 Transcriptional activator of acetoin/glycerol metabolism; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1617346..1619151) Cronobacter sakazakii ATCC BAA-894 5551709 YP_001437771.1 CDS ESA_01681 NC_009778.1 1619423 1620943 D KEGG: yps:YPTB2197 1.3e-223 probable aldehyde dehydrogenase K00128; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 1619423..1620943 Cronobacter sakazakii ATCC BAA-894 5551700 YP_001437772.1 CDS ESA_01682 NC_009778.1 1620976 1622007 D KEGG: aci:ACIAD3339 3.2e-135 adhA; alcohol dehydrogenase K00001; COG: COG1064 Zn-dependent alcohol dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 1620976..1622007 Cronobacter sakazakii ATCC BAA-894 5551699 YP_001437773.1 CDS ESA_01683 NC_009778.1 1622110 1623222 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1622110..1623222 Cronobacter sakazakii ATCC BAA-894 5551696 YP_001437774.1 CDS ESA_01684 NC_009778.1 1623224 1626745 R KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1623224..1626745) Cronobacter sakazakii ATCC BAA-894 5551686 YP_001437775.1 CDS ESA_01685 NC_009778.1 1627123 1627290 D COG: COG3042 Putative hemolysin; Psort location: nuclear, score: 23; hypothetical protein 1627123..1627290 Cronobacter sakazakii ATCC BAA-894 5551681 YP_001437776.1 CDS ESA_01686 NC_009778.1 1627291 1627713 R KEGG: net:Neut_1073 0.0038 6-aminohexanoate-dimer hydrolase; COG: COG3187 Heat shock protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1627291..1627713) Cronobacter sakazakii ATCC BAA-894 5551663 YP_001437777.1 CDS ESA_01687 NC_009778.1 1627768 1628757 R KEGG: ecj:JW1375 6.0e-157 ldhA; fermentative D-lactate dehydrogenase, NAD-dependent K03778; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1627768..1628757) Cronobacter sakazakii ATCC BAA-894 5551680 YP_001437778.1 CDS ESA_01688 NC_009778.1 1628969 1631611 D COG: NOG06225 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1628969..1631611 Cronobacter sakazakii ATCC BAA-894 5551664 YP_001437779.1 CDS ESA_01689 NC_009778.1 1631608 1631799 D COG: NOG17319 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1631608..1631799 Cronobacter sakazakii ATCC BAA-894 5551678 YP_001437780.1 CDS ESA_01690 NC_009778.1 1631811 1632131 D COG: COG3784 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1631811..1632131 Cronobacter sakazakii ATCC BAA-894 5551660 YP_001437781.1 CDS ESA_01691 NC_009778.1 1632210 1632536 D Psort location: cytoplasmic, score: 23; hypothetical protein 1632210..1632536 Cronobacter sakazakii ATCC BAA-894 5551646 YP_001437782.1 CDS ESA_01692 NC_009778.1 1632597 1633202 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1632597..1633202) Cronobacter sakazakii ATCC BAA-894 5552394 YP_001437783.1 CDS ESA_01693 NC_009778.1 1633407 1637312 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1633407..1637312 Cronobacter sakazakii ATCC BAA-894 5551641 YP_001437784.1 CDS ESA_01694 NC_009778.1 1637631 1638149 D COG: COG1943 Transposase and inactivated derivatives; Psort location: mitochondrial, score: 23; hypothetical protein 1637631..1638149 Cronobacter sakazakii ATCC BAA-894 5551632 YP_001437785.1 CDS ESA_01695 NC_009778.1 1638416 1639072 R KEGG: bcz:BCZK1776 8.4e-64 mdmC; O-methyltransferase K00599; COG: COG4122 Predicted O-methyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1638416..1639072) Cronobacter sakazakii ATCC BAA-894 5551633 YP_001437786.1 CDS ESA_01696 NC_009778.1 1639113 1640537 R COG: COG1538 Outer membrane protein; Psort location: mitochondrial, score: 23; hypothetical protein complement(1639113..1640537) Cronobacter sakazakii ATCC BAA-894 5551630 YP_001437787.1 CDS ESA_01697 NC_009778.1 1640537 1641619 R KEGG: bha:BH2653 0.0088 pdhC; pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase) K00627; COG: COG1566 Multidrug resistance efflux pump; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1640537..1641619) Cronobacter sakazakii ATCC BAA-894 5551620 YP_001437788.1 CDS ESA_01698 NC_009778.1 1641657 1643312 R COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(1641657..1643312) Cronobacter sakazakii ATCC BAA-894 5551578 YP_001437789.1 CDS ESA_01699 NC_009778.1 1643312 1643704 R KEGG: son:SO0916 0.0093 putative acetyltransferase K03828; COG: COG1846 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1643312..1643704) Cronobacter sakazakii ATCC BAA-894 5551606 YP_001437790.1 CDS ESA_01700 NC_009778.1 1643932 1644420 D KEGG: sgl:SG1900 1.9e-11 putative acetyltransferase K03829; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 1643932..1644420 Cronobacter sakazakii ATCC BAA-894 5552484 YP_001437791.1 CDS ESA_01701 NC_009778.1 1644401 1644811 D KEGG: cvi:CV0163 6.8e-46 fofB; fosfomycin resistance protein FofB K00810; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: cytoplasmic, score: 23; hypothetical protein 1644401..1644811 Cronobacter sakazakii ATCC BAA-894 5551584 YP_001437792.1 CDS ESA_01702 NC_009778.1 1644921 1645751 D KEGG: rme:Rmet_0677 0.00029 aldehyde dehydrogenase K00128; COG: COG1434 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1644921..1645751 Cronobacter sakazakii ATCC BAA-894 5551591 YP_001437793.1 CDS ESA_01703 NC_009778.1 1645934 1647394 D NAD-linked; aldehyde dehydrogenase A 1645934..1647394 Cronobacter sakazakii ATCC BAA-894 5551586 YP_001437794.1 CDS ESA_01705 NC_009778.1 1647429 1648379 R KEGG: eca:ECA2408 3.4e-92 paeX; pectin acetylesterase; COG: COG0657 Esterase/lipase; Psort location: peroxisomal, score: 9; hypothetical protein complement(1647429..1648379) Cronobacter sakazakii ATCC BAA-894 5551559 YP_001437795.1 CDS ESA_01704 NC_009778.1 1648378 1648980 D KEGG: ecs:ECs2023 2.1e-58 cytochrome b(561); COG: COG3038 Cytochrome B561; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1648378..1648980 Cronobacter sakazakii ATCC BAA-894 5551542 YP_001437796.1 CDS ESA_01706 NC_009778.1 1649144 1650469 D KEGG: cal:orf19.4356 5.2e-06 HGT3; high-affinity glucose transporter K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 1649144..1650469 Cronobacter sakazakii ATCC BAA-894 5551524 YP_001437797.1 CDS ESA_01707 NC_009778.1 1650491 1650850 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1650491..1650850) Cronobacter sakazakii ATCC BAA-894 5551545 YP_001437798.1 CDS ESA_01708 NC_009778.1 1651050 1651385 D COG: COG1937 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 1651050..1651385 Cronobacter sakazakii ATCC BAA-894 5551537 YP_001437799.1 CDS ESA_01709 NC_009778.1 1651417 1652535 D KEGG: stm:STM1627 3.3e-197 alcohol dehydrogenase class III K00001:K00121; COG: COG1062 Zn-dependent alcohol dehydrogenases, class III; Psort location: cytoplasmic, score: 23; hypothetical protein 1651417..1652535 Cronobacter sakazakii ATCC BAA-894 5551539 YP_001437800.1 CDS ESA_01710 NC_009778.1 1652699 1654396 D KEGG: ret:RHE_PF00265 0.00050 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1652699..1654396 Cronobacter sakazakii ATCC BAA-894 5551525 YP_001437801.1 CDS ESA_01711 NC_009778.1 1654590 1655090 D KEGG: rpe:RPE_3645 8.1e-25 catalase K00429; COG: COG3685 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1654590..1655090 Cronobacter sakazakii ATCC BAA-894 5551465 YP_001437802.1 CDS ESA_01712 NC_009778.1 1655211 1656278 R KEGG: bps:BPSS0877 3.1e-114 putative N-ethylmaleimide reductase; COG: COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1655211..1656278) Cronobacter sakazakii ATCC BAA-894 5552344 YP_001437803.1 CDS ESA_01713 NC_009778.1 1656392 1657321 R KEGG: shn:Shewana3_3435 0.00012 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1656392..1657321) Cronobacter sakazakii ATCC BAA-894 5552408 YP_001437804.1 CDS ESA_01714 NC_009778.1 1657330 1657659 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1657330..1657659) Cronobacter sakazakii ATCC BAA-894 5551445 YP_001437805.1 CDS ESA_01715 NC_009778.1 1657675 1659018 D COG: COG5383 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1657675..1659018 Cronobacter sakazakii ATCC BAA-894 5551487 YP_001437806.1 CDS ESA_01716 NC_009778.1 1659063 1660574 D KEGG: stm:STM1623 1.5e-206 putative carboxylesterase K03927; COG: COG2272 Carboxylesterase type B; Psort location: cytoplasmic, score: 23; hypothetical protein 1659063..1660574 Cronobacter sakazakii ATCC BAA-894 5549896 YP_001437807.1 CDS mdoD NC_009778.1 1661137 1662792 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1661137..1662792 Cronobacter sakazakii ATCC BAA-894 5552093 YP_001437808.1 CDS ESA_01718 NC_009778.1 1662946 1663506 D KEGG: sfl:SF1783 1.3e-58 rimL; acetylation of N-terminal serine of 30S ribosomal subunit protein L7; acetyl transferase K03817; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; ribosomal-protein-L7/L12-serine acetyltransferase 1662946..1663506 Cronobacter sakazakii ATCC BAA-894 5548285 YP_001437809.1 CDS ESA_01719 NC_009778.1 1663503 1664483 R KEGG: syc:syc1734_d 0.0037 acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine o-acyltransferase K00677; COG: NOG06285 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1663503..1664483) Cronobacter sakazakii ATCC BAA-894 5548468 YP_001437810.1 CDS ESA_01720 NC_009778.1 1664476 1664601 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1664476..1664601) Cronobacter sakazakii ATCC BAA-894 5551896 YP_001437811.1 CDS ESA_01721 NC_009778.1 1664631 1665224 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1664631..1665224 Cronobacter sakazakii ATCC BAA-894 5551925 YP_001437812.1 CDS ESA_01722 NC_009778.1 1665440 1666108 D COG: NOG06284 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1665440..1666108 Cronobacter sakazakii ATCC BAA-894 5550249 YP_001437813.1 CDS ESA_01723 NC_009778.1 1666140 1667345 R KEGG: ade:Adeh_3654 0.0043 NADH dehydrogenase (quinone) K05903; COG: COG3135 Uncharacterized protein involved in benzoate metabolism; Psort location: plasma membrane, score: 23; hypothetical protein complement(1666140..1667345) Cronobacter sakazakii ATCC BAA-894 5551460 YP_001437814.1 CDS ESA_01724 NC_009778.1 1667397 1667927 D KEGG: psp:PSPPH_2917 0.00023 DNA-binding protein K00517; COG: COG1396 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 1667397..1667927 Cronobacter sakazakii ATCC BAA-894 5551379 YP_001437815.1 CDS ESA_01725 NC_009778.1 1668164 1670128 D KEGG: sec:SC1601 0. ydcP; putative collagenase K08303; COG: COG0826 Collagenase and related proteases; Psort location: mitochondrial, score: 23; hypothetical protein 1668164..1670128 Cronobacter sakazakii ATCC BAA-894 5551478 YP_001437816.1 CDS ESA_01726 NC_009778.1 1670318 1670749 D KEGG: stm:STM1998 1.9e-34 umuD; error-prone repair: SOS-response transcriptional repressors (LexA homologs, RecA-mediated autopeptidases) K03503; COG: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Psort location: cytoplasmic, score: 23; hypothetical protein 1670318..1670749 Cronobacter sakazakii ATCC BAA-894 5551053 YP_001437817.1 CDS ESA_01727 NC_009778.1 1670751 1672019 D KEGG: stm:STM1997 7.7e-141 umuC; error-prone repair: component of DNA polymerase V with UmuD' K03502; COG: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Psort location: cytoplasmic, score: 23; hypothetical protein 1670751..1672019 Cronobacter sakazakii ATCC BAA-894 5551042 YP_001437818.1 CDS ESA_01728 NC_009778.1 1672133 1672471 R COG: COG4405 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1672133..1672471) Cronobacter sakazakii ATCC BAA-894 5552126 YP_001437819.1 CDS ESA_01729 NC_009778.1 1673046 1673405 D COG: COG2076 Membrane transporters of cations and cationic drugs; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1673046..1673405 Cronobacter sakazakii ATCC BAA-894 5551437 YP_001437820.1 CDS ESA_01730 NC_009778.1 1673392 1673721 D with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1673392..1673721 Cronobacter sakazakii ATCC BAA-894 5551444 YP_001437821.1 CDS ESA_01731 NC_009778.1 1673763 1674584 R KEGG: sty:STY1583 4.6e-111 putative secreted protein K04775; COG: COG3591 V8-like Glu-specific endopeptidase; Psort location: mitochondrial, score: 23; hypothetical protein complement(1673763..1674584) Cronobacter sakazakii ATCC BAA-894 5551399 YP_001437822.1 CDS ESA_01732 NC_009778.1 1674688 1674945 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1674688..1674945) Cronobacter sakazakii ATCC BAA-894 5551398 YP_001437823.1 CDS ESA_01733 NC_009778.1 1674976 1676460 R KEGG: yps:YPTB2232 5.0e-185 putative carboxypeptidase K01299; COG: COG2317 Zn-dependent carboxypeptidase; Psort location: mitochondrial, score: 23; hypothetical protein complement(1674976..1676460) Cronobacter sakazakii ATCC BAA-894 5551390 YP_001437824.1 CDS ESA_01734 NC_009778.1 1676534 1677784 R KEGG: shn:Shewana3_1692 9.1e-51 Xaa-His dipeptidase K01270; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1676534..1677784) Cronobacter sakazakii ATCC BAA-894 5551397 YP_001437825.1 CDS ESA_01735 NC_009778.1 1677906 1678838 D KEGG: shn:Shewana3_3435 1.3e-26 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1677906..1678838 Cronobacter sakazakii ATCC BAA-894 5551393 YP_001437826.1 CDS ESA_01736 NC_009778.1 1678933 1680150 D KEGG: eci:UTI89_C1781 4.6e-182 mlc; putative NAGC-like transcriptional regulator K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 1678933..1680150 Cronobacter sakazakii ATCC BAA-894 5551392 YP_001437827.1 CDS ESA_01737 NC_009778.1 1680254 1680958 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase 1680254..1680958 Cronobacter sakazakii ATCC BAA-894 5551366 YP_001437828.1 CDS ESA_01738 NC_009778.1 1681089 1682234 R KEGG: bur:Bcep18194_C7553 8.5e-135 ABC glycine betaine/L-proline transporter, ATPase subunit K05847; COG: COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1681089..1682234) Cronobacter sakazakii ATCC BAA-894 5551310 YP_001437829.1 CDS ESA_01739 NC_009778.1 1682234 1682884 R KEGG: lwe:lwe1439 7.3e-42 glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; COG: COG1174 ABC-type proline/glycine betaine transport systems, permease component; Psort location: plasma membrane, score: 23; hypothetical protein complement(1682234..1682884) Cronobacter sakazakii ATCC BAA-894 5551357 YP_001437830.1 CDS ESA_01740 NC_009778.1 1682891 1683796 R KEGG: lwe:lwe1439 4.1e-32 glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; COG: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1682891..1683796) Cronobacter sakazakii ATCC BAA-894 5551350 YP_001437831.1 CDS ESA_01741 NC_009778.1 1683813 1684526 R KEGG: lwe:lwe1439 5.4e-37 glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; COG: COG1174 ABC-type proline/glycine betaine transport systems, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1683813..1684526) Cronobacter sakazakii ATCC BAA-894 5551326 YP_001437832.1 CDS ESA_01742 NC_009778.1 1684855 1685190 D KEGG: ctr:CT219 0.0074 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179; COG: COG3136 Uncharacterized membrane protein required for alginate biosynthesis; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1684855..1685190 Cronobacter sakazakii ATCC BAA-894 5551346 YP_001437833.1 CDS ESA_01743 NC_009778.1 1685187 1685795 R binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD complement(1685187..1685795) Cronobacter sakazakii ATCC BAA-894 5552432 YP_001437834.1 CDS ESA_01744 NC_009778.1 1685841 1686689 R KEGG: eci:UTI89_C1777 4.1e-103 ynfH; anaerobic dimethyl sulfoxide reductase chain YnfH K07312; COG: COG3302 DMSO reductase anchor subunit; Psort location: plasma membrane, score: 23; hypothetical protein complement(1685841..1686689) Cronobacter sakazakii ATCC BAA-894 5551347 YP_001437835.1 CDS ESA_01745 NC_009778.1 1686691 1687308 R KEGG: ecp:ECP_0909 2.5e-110 anaerobic dimethyl sulfoxide reductase, subunit B K07307; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: nuclear, score: 23; hypothetical protein complement(1686691..1687308) Cronobacter sakazakii ATCC BAA-894 5551349 YP_001437836.1 CDS ESA_01746 NC_009778.1 1687318 1689753 R KEGG: eco:b0894 0. dmsA; anaerobic dimethyl sulfoxide (DMSO) reductase, subunit A K07306; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1687318..1689753) Cronobacter sakazakii ATCC BAA-894 5551344 YP_001437837.1 CDS ESA_01747 NC_009778.1 1690034 1690330 R COG: NOG12175 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1690034..1690330) Cronobacter sakazakii ATCC BAA-894 5551332 YP_001437838.1 CDS ESA_01748 NC_009778.1 1690408 1691154 D COG: NOG06202 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 1690408..1691154 Cronobacter sakazakii ATCC BAA-894 5551334 YP_001437839.1 CDS ESA_01749 NC_009778.1 1691207 1691767 R KEGG: sec:SC1519 3.6e-88 speG; spermidine N1-acetyltransferase K00657; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1691207..1691767) Cronobacter sakazakii ATCC BAA-894 5551333 YP_001437840.1 CDS ESA_01750 NC_009778.1 1691834 1692163 R COG: NOG11441 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1691834..1692163) Cronobacter sakazakii ATCC BAA-894 5551316 YP_001437841.1 CDS ESA_01751 NC_009778.1 1692267 1692605 D COG: COG1742 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 23; hypothetical protein 1692267..1692605 Cronobacter sakazakii ATCC BAA-894 5551314 YP_001437842.1 CDS ESA_01752 NC_009778.1 1692692 1693975 D KEGG: eci:UTI89_C1768 1.2e-215 rspA; starvation sensing protein RspA K08323; COG: COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein 1692692..1693975 Cronobacter sakazakii ATCC BAA-894 5551960 YP_001437843.1 CDS ESA_01753 NC_009778.1 1694034 1695311 D COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1694034..1695311 Cronobacter sakazakii ATCC BAA-894 5551317 YP_001437844.1 CDS ESA_01754 NC_009778.1 1695477 1696943 D KEGG: sty:STY1553 1.3e-202 putative D-mannonate oxidoreductase K00040; COG: COG0246 Mannitol-1-phosphate/altronate dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 1695477..1696943 Cronobacter sakazakii ATCC BAA-894 5551320 YP_001437845.1 CDS ESA_01755 NC_009778.1 1697099 1697302 R COG: NOG13886 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1697099..1697302) Cronobacter sakazakii ATCC BAA-894 5551301 YP_001437846.1 CDS ESA_01756 NC_009778.1 1697427 1698347 R COG: NOG18492 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1697427..1698347) Cronobacter sakazakii ATCC BAA-894 5551296 YP_001437847.1 CDS ESA_01757 NC_009778.1 1698360 1699046 R KEGG: msm:MSMEG_3400 7.8e-08 glutamyl-tRNA(Gln) amidotransferase subunit A K01957; COG: COG1802 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1698360..1699046) Cronobacter sakazakii ATCC BAA-894 5551282 YP_001437848.1 CDS ESA_01758 NC_009778.1 1699135 1699881 R NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase complement(1699135..1699881) Cronobacter sakazakii ATCC BAA-894 5551277 YP_001437849.1 CDS ESA_01759 NC_009778.1 1699957 1702086 D KEGG: ece:Z2160 1.6e-259 dcp; dipeptidyl carboxypeptidase II K01284; COG: COG0339 Zn-dependent oligopeptidases; Psort location: cytoplasmic, score: 23; dipeptidyl carboxypeptidase II 1699957..1702086 Cronobacter sakazakii ATCC BAA-894 5552251 YP_001437850.1 CDS ESA_01760 NC_009778.1 1702410 1703213 R KEGG: rba:RB997 0.00082 ogt; probable O-linked GlcNAc transferase K00754; COG: COG0789 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1702410..1703213) Cronobacter sakazakii ATCC BAA-894 5551288 YP_001437851.1 CDS ESA_01761 NC_009778.1 1703377 1704288 R COG: COG3781 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1703377..1704288) Cronobacter sakazakii ATCC BAA-894 5551266 YP_001437852.1 CDS ESA_01762 NC_009778.1 1704369 1704503 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1704369..1704503) Cronobacter sakazakii ATCC BAA-894 5551241 YP_001437853.1 CDS ESA_01763 NC_009778.1 1704860 1705048 D Psort location: cytoplasmic, score: 23; hypothetical protein 1704860..1705048 Cronobacter sakazakii ATCC BAA-894 5551252 YP_001437854.1 CDS ESA_01764 NC_009778.1 1705131 1705904 D COG: NOG09007 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1705131..1705904 Cronobacter sakazakii ATCC BAA-894 5551221 YP_001437855.1 CDS ESA_01765 NC_009778.1 1706015 1707217 D catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1706015..1707217 Cronobacter sakazakii ATCC BAA-894 5552459 YP_001437856.1 CDS ESA_01766 NC_009778.1 1707734 1707997 D Psort location: mitochondrial, score: 23; hypothetical protein 1707734..1707997 Cronobacter sakazakii ATCC BAA-894 5551230 YP_001437857.1 CDS ESA_01767 NC_009778.1 1708096 1709910 D catalyzes the hydrolysis of allophanate; allophanate hydrolase 1708096..1709910 Cronobacter sakazakii ATCC BAA-894 5551220 YP_001437858.1 CDS ESA_01768 NC_009778.1 1709888 1713529 D KEGG: eca:ECA2142 0. urea amidolyase K01941; COG: COG0439 Biotin carboxylase; Psort location: cytoplasmic, score: 23; hypothetical protein 1709888..1713529 Cronobacter sakazakii ATCC BAA-894 5551200 YP_001437859.1 CDS ESA_01769 NC_009778.1 1713674 1714405 D KEGG: msm:MSMEG_3400 4.5e-05 glutamyl-tRNA(Gln) amidotransferase subunit A K01957; COG: COG1802 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 1713674..1714405 Cronobacter sakazakii ATCC BAA-894 5551212 YP_001437860.1 CDS ESA_01770 NC_009778.1 1714441 1715712 D COG: COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; Psort location: mitochondrial, score: 23; hypothetical protein 1714441..1715712 Cronobacter sakazakii ATCC BAA-894 5551209 YP_001437861.1 CDS ESA_01771 NC_009778.1 1715896 1717461 D KEGG: fal:FRAAL3359 1.7e-12 putative sulfate-transporting ATPase K06020; COG: COG0559 Branched-chain amino acid ABC-type transport system, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1715896..1717461 Cronobacter sakazakii ATCC BAA-894 5551199 YP_001437862.1 CDS ESA_01772 NC_009778.1 1717458 1718531 D KEGG: reh:H16_A3653 2.8e-13 ABC-type transporter, ATPase and permease components; COG: COG4177 ABC-type branched-chain amino acid transport system, permease component; Psort location: plasma membrane, score: 23; hypothetical protein 1717458..1718531 Cronobacter sakazakii ATCC BAA-894 5551188 YP_001437863.1 CDS ESA_01773 NC_009778.1 1718531 1719328 D KEGG: pen:PSEEN4891 4.4e-90 branched-chain amino acid transport ABC transporter, ATP-binding component; COG: COG4674 Uncharacterized ABC-type transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 1718531..1719328 Cronobacter sakazakii ATCC BAA-894 5551194 YP_001437864.1 CDS ESA_01774 NC_009778.1 1719338 1720036 D KEGG: pen:PSEEN4892 6.8e-94 branched-chain amino acid ABC transporter, ATP-binding protein; COG: COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 1719338..1720036 Cronobacter sakazakii ATCC BAA-894 5551181 YP_001437865.1 CDS ESA_01775 NC_009778.1 1720214 1720528 D COG: NOG11501 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1720214..1720528 Cronobacter sakazakii ATCC BAA-894 5551175 YP_001437866.1 CDS ESA_01777 NC_009778.1 1720535 1720687 R Psort location: nuclear, score: 23; hypothetical protein complement(1720535..1720687) Cronobacter sakazakii ATCC BAA-894 5551172 YP_001437867.1 CDS ESA_01776 NC_009778.1 1720611 1721021 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1720611..1721021 Cronobacter sakazakii ATCC BAA-894 5551148 YP_001437868.1 CDS ESA_01778 NC_009778.1 1721439 1722233 R KEGG: nwi:Nwi_0782 3.7e-09 integrase, catalytic region K00986; COG: COG2801 Transposase and inactivated derivatives; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1721439..1722233) Cronobacter sakazakii ATCC BAA-894 5551164 YP_001437869.1 CDS ESA_01779 NC_009778.1 1722258 1722527 D Psort location: cytoplasmic, score: 23; hypothetical protein 1722258..1722527 Cronobacter sakazakii ATCC BAA-894 5551157 YP_001437870.1 CDS ESA_01780 NC_009778.1 1722514 1722648 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1722514..1722648) Cronobacter sakazakii ATCC BAA-894 5551151 YP_001437871.1 CDS ESA_01781 NC_009778.1 1722846 1724345 R KEGG: cel:K12C11.4 0.00045 dapk-1; DAP (Death-Associated Protein) Kinase homolog K08803; COG: COG0515 Serine/threonine protein kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1722846..1724345) Cronobacter sakazakii ATCC BAA-894 5551149 YP_001437872.1 CDS ESA_01782 NC_009778.1 1724371 1726008 R COG: NOG12280 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1724371..1726008) Cronobacter sakazakii ATCC BAA-894 5551138 YP_001437873.1 CDS ESA_01783 NC_009778.1 1726008 1727048 R COG: COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1726008..1727048) Cronobacter sakazakii ATCC BAA-894 5551137 YP_001437874.1 CDS ESA_01784 NC_009778.1 1727134 1727772 R KEGG: rxy:Rxyl_0636 0.0062 von Willebrand factor, type A; COG: COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1727134..1727772) Cronobacter sakazakii ATCC BAA-894 5551126 YP_001437875.1 CDS ESA_01785 NC_009778.1 1727772 1728413 R COG: COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1727772..1728413) Cronobacter sakazakii ATCC BAA-894 5551125 YP_001437876.1 CDS ESA_01786 NC_009778.1 1728436 1729029 R COG: COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1728436..1729029) Cronobacter sakazakii ATCC BAA-894 5551116 YP_001437877.1 CDS ESA_01787 NC_009778.1 1729071 1729232 R Psort location: nuclear, score: 23; hypothetical protein complement(1729071..1729232) Cronobacter sakazakii ATCC BAA-894 5551115 YP_001437878.1 CDS ESA_01788 NC_009778.1 1729237 1729368 D Psort location: nuclear, score: 23; hypothetical protein 1729237..1729368 Cronobacter sakazakii ATCC BAA-894 5551096 YP_001437879.1 CDS ESA_01789 NC_009778.1 1729538 1730005 R COG: NOG27346 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1729538..1730005) Cronobacter sakazakii ATCC BAA-894 5551118 YP_001437880.1 CDS ESA_01790 NC_009778.1 1730023 1731231 R COG: NOG23976 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(1730023..1731231) Cronobacter sakazakii ATCC BAA-894 5551093 YP_001437881.1 CDS ESA_01791 NC_009778.1 1731242 1732198 R KEGG: bpm:BURPS1710b_A0703 4.4e-05 citrate lyase, beta subunit, putative K01644; COG: COG2301 Citrate lyase beta subunit; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1731242..1732198) Cronobacter sakazakii ATCC BAA-894 5551099 YP_001437882.1 CDS ESA_01792 NC_009778.1 1732198 1733277 R COG: NOG09666 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1732198..1733277) Cronobacter sakazakii ATCC BAA-894 5551102 YP_001437883.1 CDS ESA_01793 NC_009778.1 1733279 1734052 R COG: NOG13540 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1733279..1734052) Cronobacter sakazakii ATCC BAA-894 5551092 YP_001437884.1 CDS ESA_01794 NC_009778.1 1734045 1735187 R COG: NOG08627 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1734045..1735187) Cronobacter sakazakii ATCC BAA-894 5551090 YP_001437885.1 CDS ESA_01795 NC_009778.1 1735197 1736279 R COG: NOG11390 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(1735197..1736279) Cronobacter sakazakii ATCC BAA-894 5551065 YP_001437886.1 CDS ESA_01796 NC_009778.1 1736575 1737156 D COG: COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; Psort location: cytoplasmic, score: 23; hypothetical protein 1736575..1737156 Cronobacter sakazakii ATCC BAA-894 5551080 YP_001437887.1 CDS ESA_01797 NC_009778.1 1737156 1738313 D COG: COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; Psort location: cytoplasmic, score: 23; hypothetical protein 1737156..1738313 Cronobacter sakazakii ATCC BAA-894 5551079 YP_001437888.1 CDS ESA_01798 NC_009778.1 1738336 1738791 D COG: COG3793 Tellurite resistance protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1738336..1738791 Cronobacter sakazakii ATCC BAA-894 5551072 YP_001437889.1 CDS ESA_01799 NC_009778.1 1738814 1739854 D COG: COG0861 Membrane protein TerC, possibly involved in tellurium resistance; Psort location: plasma membrane, score: 23; hypothetical protein 1738814..1739854 Cronobacter sakazakii ATCC BAA-894 5551070 YP_001437890.1 CDS ESA_01800 NC_009778.1 1739960 1740481 D COG: COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; Psort location: cytoplasmic, score: 23; hypothetical protein 1739960..1740481 Cronobacter sakazakii ATCC BAA-894 5549439 YP_001437891.1 CDS ESA_01801 NC_009778.1 1740515 1741126 D COG: COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; Psort location: cytoplasmic, score: 23; hypothetical protein 1740515..1741126 Cronobacter sakazakii ATCC BAA-894 5548287 YP_001437892.1 CDS ESA_01802 NC_009778.1 1741451 1742692 D COG: COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; Psort location: cytoplasmic, score: 23; hypothetical protein 1741451..1742692 Cronobacter sakazakii ATCC BAA-894 5551077 YP_001437893.1 CDS ESA_01803 NC_009778.1 1743388 1743657 R COG: NOG04673 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1743388..1743657) Cronobacter sakazakii ATCC BAA-894 5551048 YP_001437894.1 CDS ESA_01804 NC_009778.1 1743837 1743995 R Psort location: nuclear, score: 23; hypothetical protein complement(1743837..1743995) Cronobacter sakazakii ATCC BAA-894 5551038 YP_001437895.1 CDS ESA_01805 NC_009778.1 1744515 1745708 R YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE complement(1744515..1745708) Cronobacter sakazakii ATCC BAA-894 5551009 YP_001437896.1 CDS ESA_01806 NC_009778.1 1745916 1746812 D KEGG: pae:PA1977 1.5e-08 sensor protein GLPS; COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: plasma membrane, score: 23; O-acetylserine/cysteine export protein 1745916..1746812 Cronobacter sakazakii ATCC BAA-894 5551041 YP_001437897.1 CDS ESA_01807 NC_009778.1 1746838 1747050 R COG: NOG15370 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1746838..1747050) Cronobacter sakazakii ATCC BAA-894 5551002 YP_001437898.1 CDS ESA_01808 NC_009778.1 1747121 1747495 R transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA complement(1747121..1747495) Cronobacter sakazakii ATCC BAA-894 5551034 YP_001437899.1 CDS ESA_01809 NC_009778.1 1747514 1748005 R Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR complement(1747514..1748005) Cronobacter sakazakii ATCC BAA-894 5552179 YP_001437900.1 CDS ESA_01810 NC_009778.1 1748195 1749469 R KEGG: dre:30298 8.5e-07 jak2b; Janus kinase 2b K04447; COG: COG2814 Arabinose efflux permease; Psort location: plasma membrane, score: 23; sugar efflux transporter complement(1748195..1749469) Cronobacter sakazakii ATCC BAA-894 5551019 YP_001437901.1 CDS ESA_01811 NC_009778.1 1749604 1750401 D KEGG: reh:H16_A2781 5.2e-10 predicted epimerase, PhzC/PhzF homolog; COG: COG0384 Predicted epimerase, PhzC/PhzF homolog; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1749604..1750401 Cronobacter sakazakii ATCC BAA-894 5551016 YP_001437902.1 CDS ESA_01812 NC_009778.1 1750437 1751357 R KEGG: lwe:lwe1547 5.9e-111 ldhB; L-lactate dehydrogenase K00016; COG: COG0039 Malate/lactate dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1750437..1751357) Cronobacter sakazakii ATCC BAA-894 5551004 YP_001437903.1 CDS ESA_01813 NC_009778.1 1751551 1752024 D KEGG: cvi:CV2951 3.7e-31 probable acetyltransferase K03829; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 1751551..1752024 Cronobacter sakazakii ATCC BAA-894 5552240 YP_001437904.1 CDS ESA_01814 NC_009778.1 1751984 1752856 R KEGG: shn:Shewana3_3435 1.2e-09 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1751984..1752856) Cronobacter sakazakii ATCC BAA-894 5551007 YP_001437905.1 CDS ESA_01816 NC_009778.1 1752890 1754344 R KEGG: bpm:BURPS1710b_3227 0.0014 fahA; fumarylacetoacetase K01555; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1752890..1754344) Cronobacter sakazakii ATCC BAA-894 5551006 YP_001437906.1 CDS ESA_01815 NC_009778.1 1752998 1754386 D in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate semialdehyde dehydrogenase 1752998..1754386 Cronobacter sakazakii ATCC BAA-894 5550983 YP_001437907.1 CDS ESA_01817 NC_009778.1 1754648 1756237 D KEGG: pae:PA1438 2.1e-05 probable two-component sensor K07644; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1754648..1756237 Cronobacter sakazakii ATCC BAA-894 5551000 YP_001437908.1 CDS ESA_01818 NC_009778.1 1756289 1757215 D catalyzes the formation of glutamate from glutamine; glutaminase 1756289..1757215 Cronobacter sakazakii ATCC BAA-894 5550946 YP_001437909.1 CDS ESA_01819 NC_009778.1 1757225 1757572 D COG: NOG13916 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1757225..1757572 Cronobacter sakazakii ATCC BAA-894 5550996 YP_001437910.1 CDS ESA_01820 NC_009778.1 1757701 1759143 D KEGG: bpm:BURPS1710b_A1493 1.4e-25 GGDEF domain protein; COG: COG2199 FOG: GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1757701..1759143 Cronobacter sakazakii ATCC BAA-894 5550987 YP_001437911.1 CDS ESA_01821 NC_009778.1 1759301 1760359 D KEGG: eci:UTI89_C0404 2.3e-45 yaiC; hypothetical protein; COG: COG2199 FOG: GGDEF domain; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 1759301..1760359 Cronobacter sakazakii ATCC BAA-894 5550997 YP_001437912.1 CDS ESA_01822 NC_009778.1 1760429 1761400 D KEGG: lpn:lpg1490 3.1e-34 cyaA; adenylate cyclase PLUS two component hybrid sensor and regulator K01768; COG: COG2199 FOG: GGDEF domain; Psort location: cytoplasmic, score: 23; hypothetical protein 1760429..1761400 Cronobacter sakazakii ATCC BAA-894 5550973 YP_001437913.1 CDS ESA_01823 NC_009778.1 1761602 1762015 D KEGG: cvi:CV3493 4.6e-24 probable acetyltransferase protein K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 1761602..1762015 Cronobacter sakazakii ATCC BAA-894 5550985 YP_001437914.1 CDS ESA_01824 NC_009778.1 1762133 1763584 D catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1762133..1763584 Cronobacter sakazakii ATCC BAA-894 5550959 YP_001437915.1 CDS ESA_01825 NC_009778.1 1763855 1765834 D KEGG: pen:PSEEN0445 4.9e-25 estA; esterase EstA precursor K01044; COG: COG3240 Phospholipase/leciTHInase/hemolysin; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1763855..1765834 Cronobacter sakazakii ATCC BAA-894 5550976 YP_001437916.1 CDS treF NC_009778.1 1765899 1767539 R cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase complement(1765899..1767539) Cronobacter sakazakii ATCC BAA-894 5550944 YP_001437917.1 CDS ESA_01827 NC_009778.1 1767685 1769895 R KEGG: tth:TT_P0222 1.7e-88 probable beta-galactosidase K01190; COG: COG3250 Beta-galactosidase/beta-glucuronidase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1767685..1769895) Cronobacter sakazakii ATCC BAA-894 5550933 YP_001437918.1 CDS ESA_01828 NC_009778.1 1769892 1772573 R KEGG: azo:azo3685 4.7e-118 putative hybrid sensor and regulator protein; COG: COG0642 Signal transduction histidine kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1769892..1772573) Cronobacter sakazakii ATCC BAA-894 5552301 YP_001437919.1 CDS ESA_01829 NC_009778.1 1772570 1773007 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1772570..1773007) Cronobacter sakazakii ATCC BAA-894 5550960 YP_001437920.1 CDS ESA_01830 NC_009778.1 1773004 1774401 R COG: NOG25409 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1773004..1774401) Cronobacter sakazakii ATCC BAA-894 5550967 YP_001437921.1 CDS ESA_01831 NC_009778.1 1774386 1775936 R COG: NOG25409 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1774386..1775936) Cronobacter sakazakii ATCC BAA-894 5550962 YP_001437922.1 CDS ESA_01832 NC_009778.1 1775933 1777273 R COG: NOG25409 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1775933..1777273) Cronobacter sakazakii ATCC BAA-894 5550956 YP_001437923.1 CDS ESA_01833 NC_009778.1 1777270 1779084 R KEGG: nca:Noca_2832 1.4e-61 cellulose synthase (UDP-forming); COG: COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1777270..1779084) Cronobacter sakazakii ATCC BAA-894 5552281 YP_001437924.1 CDS ESA_01835 NC_009778.1 1779179 1779439 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1779179..1779439) Cronobacter sakazakii ATCC BAA-894 5550954 YP_001437925.1 CDS ESA_01834 NC_009778.1 1779412 1780632 D COG: COG4645 Uncharacterized protein conserved in bacteria; Psort location: plasma membrane, score: 23; hypothetical protein 1779412..1780632 Cronobacter sakazakii ATCC BAA-894 5550923 YP_001437926.1 CDS ESA_01836 NC_009778.1 1780647 1781561 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1780647..1781561 Cronobacter sakazakii ATCC BAA-894 5550949 YP_001437927.1 CDS ESA_01837 NC_009778.1 1781571 1782791 D KEGG: ava:Ava_3723 6.7e-39 response regulator receiver (CheY) modulated serine phosphatase K01079; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 1781571..1782791 Cronobacter sakazakii ATCC BAA-894 5550945 YP_001437928.1 CDS ESA_01838 NC_009778.1 1782781 1783122 D KEGG: ter:Tery_1523 6.4e-07 anti-sigma-factor antagonist and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: cytoplasmic, score: 23; hypothetical protein 1782781..1783122 Cronobacter sakazakii ATCC BAA-894 5550937 YP_001437929.1 CDS ESA_01839 NC_009778.1 1783127 1783540 D KEGG: rde:RD1_0027 7.5e-08 rsbW; serine-protein kinase, putative K08282; Psort location: cytoplasmic, score: 23; hypothetical protein 1783127..1783540 Cronobacter sakazakii ATCC BAA-894 5550936 YP_001437930.1 CDS ESA_01840 NC_009778.1 1783537 1784136 R KEGG: psp:PSPPH_2917 1.3e-08 DNA-binding protein K00517; COG: COG1396 Predicted transcriptional regulators; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1783537..1784136) Cronobacter sakazakii ATCC BAA-894 5550927 YP_001437931.1 CDS ESA_01841 NC_009778.1 1784201 1784890 D COG: COG3382 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1784201..1784890 Cronobacter sakazakii ATCC BAA-894 5550919 YP_001437932.1 CDS ESA_01842 NC_009778.1 1784907 1785428 D KEGG: mkm:Mkms_3050 2.3e-13 dephospho-CoA kinase K00859; COG: COG2320 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1784907..1785428 Cronobacter sakazakii ATCC BAA-894 5550929 YP_001437933.1 CDS ESA_01843 NC_009778.1 1785425 1785757 D COG: NOG11501 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1785425..1785757 Cronobacter sakazakii ATCC BAA-894 5550922 YP_001437934.1 CDS ESA_01844 NC_009778.1 1785750 1785881 D Psort location: cytoplasmic, score: 23; hypothetical protein 1785750..1785881 Cronobacter sakazakii ATCC BAA-894 5550917 YP_001437935.1 CDS ESA_01845 NC_009778.1 1786375 1786968 D COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1786375..1786968 Cronobacter sakazakii ATCC BAA-894 5550914 YP_001437936.1 CDS ESA_01847 NC_009778.1 1787361 1788356 R KEGG: bur:Bcep18194_C6615 1.8e-84 alpha/beta hydrolase K00433; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein complement(1787361..1788356) Cronobacter sakazakii ATCC BAA-894 5550899 YP_001437937.1 CDS ESA_01846 NC_009778.1 1788355 1788732 D KEGG: eci:UTI89_C3737 8.4e-09 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 1788355..1788732 Cronobacter sakazakii ATCC BAA-894 5550862 YP_001437938.1 CDS ESA_01848 NC_009778.1 1788970 1789110 R Psort location: nuclear, score: 23; hypothetical protein complement(1788970..1789110) Cronobacter sakazakii ATCC BAA-894 5550889 YP_001437939.1 CDS ESA_01849 NC_009778.1 1789205 1789774 D KEGG: eci:UTI89_C1901 1.0e-33 nlpC; probable lipoprotein NlpC precursor; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1789205..1789774 Cronobacter sakazakii ATCC BAA-894 5550875 YP_001437940.1 CDS ESA_01850 NC_009778.1 1789797 1790195 D Psort location: mitochondrial, score: 23; hypothetical protein 1789797..1790195 Cronobacter sakazakii ATCC BAA-894 5551932 YP_001437941.1 CDS ESA_01851 NC_009778.1 1789812 1790171 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1789812..1790171) Cronobacter sakazakii ATCC BAA-894 5550882 YP_001437942.1 CDS ESA_01852 NC_009778.1 1790264 1791565 R KEGG: psp:PSPPH_3703 1.1e-123 L-sorbosone dehydrogenase K00100; COG: COG2133 Glucose/sorbosone dehydrogenases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1790264..1791565) Cronobacter sakazakii ATCC BAA-894 5550872 YP_001437943.1 CDS ESA_01853 NC_009778.1 1791578 1792003 R COG: COG4244 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1791578..1792003) Cronobacter sakazakii ATCC BAA-894 5550842 YP_001437944.1 CDS ESA_01854 NC_009778.1 1792172 1793617 R COG: COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1792172..1793617) Cronobacter sakazakii ATCC BAA-894 5550874 YP_001437945.1 CDS ESA_01855 NC_009778.1 1793571 1793861 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1793571..1793861) Cronobacter sakazakii ATCC BAA-894 5550864 YP_001437946.1 CDS ESA_01856 NC_009778.1 1793908 1794243 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1793908..1794243) Cronobacter sakazakii ATCC BAA-894 5550848 YP_001437947.1 CDS ESA_01857 NC_009778.1 1794391 1795365 D KEGG: cno:NT01CX_0232 5.8e-22 UV DNA damage endonuclease (UV-endonuclease) UvdE; COG: COG4294 UV damage repair endonuclease; Psort location: cytoplasmic, score: 23; hypothetical protein 1794391..1795365 Cronobacter sakazakii ATCC BAA-894 5549939 YP_001437948.1 CDS ESA_01858 NC_009778.1 1795564 1796499 R KEGG: azo:azo2292 2.5e-05 ada; methylated-DNA--[protein]-cysteine S-methyltransferase K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: mitochondrial, score: 23; hypothetical protein complement(1795564..1796499) Cronobacter sakazakii ATCC BAA-894 5549785 YP_001437949.1 CDS ESA_01859 NC_009778.1 1796685 1797422 D KEGG: ret:RHE_CH00288 3.0e-75 putative oxidoreductase protein K00059; COG: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Psort location: cytoplasmic, score: 23; hypothetical protein 1796685..1797422 Cronobacter sakazakii ATCC BAA-894 5550154 YP_001437950.1 CDS ESA_01860 NC_009778.1 1797425 1797667 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1797425..1797667) Cronobacter sakazakii ATCC BAA-894 5549842 YP_001437951.1 CDS ESA_01861 NC_009778.1 1797719 1797916 D Psort location: cytoplasmic, score: 23; hypothetical protein 1797719..1797916 Cronobacter sakazakii ATCC BAA-894 5549868 YP_001437952.1 CDS ESA_01862 NC_009778.1 1797918 1798682 D COG: NOG22744 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1797918..1798682 Cronobacter sakazakii ATCC BAA-894 5551062 YP_001437953.1 CDS ESA_01863 NC_009778.1 1798746 1799339 D KEGG: mbo:Mb3598c 0.00035 possible oxidoreductase; COG: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; Psort location: cytoplasmic, score: 23; hypothetical protein 1798746..1799339 Cronobacter sakazakii ATCC BAA-894 5549563 YP_001437954.1 CDS ESA_01864 NC_009778.1 1799525 1799917 R COG: COG3070 Regulator of competence-specific genes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1799525..1799917) Cronobacter sakazakii ATCC BAA-894 5549629 YP_001437955.1 CDS ESA_01865 NC_009778.1 1799989 1800159 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1799989..1800159) Cronobacter sakazakii ATCC BAA-894 5549672 YP_001437956.1 CDS ESA_01866 NC_009778.1 1800370 1801134 D KEGG: rpa:RPA0109 9.2e-58 putative 3-oxoacyl-(acyl carrier ptn) reductase K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 1800370..1801134 Cronobacter sakazakii ATCC BAA-894 5549920 YP_001437957.1 CDS ESA_01867 NC_009778.1 1801190 1802275 R KEGG: rfr:Rfer_2439 1.8e-134 alcohol dehydrogenase, zinc-binding K00002; COG: COG1064 Zn-dependent alcohol dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1801190..1802275) Cronobacter sakazakii ATCC BAA-894 5549748 YP_001437958.1 CDS ESA_01868 NC_009778.1 1802437 1803021 R KEGG: sru:SRU_2774 4.1e-16 pcaC; 4-carboxymuconolactone decarboxylase domain protein K01607; COG: COG2128 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1802437..1803021) Cronobacter sakazakii ATCC BAA-894 5550078 YP_001437959.1 CDS ESA_01869 NC_009778.1 1803093 1804007 D KEGG: bli:BL05281 4.0e-07 adaA; methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 1803093..1804007 Cronobacter sakazakii ATCC BAA-894 5549803 YP_001437960.1 CDS ESA_01870 NC_009778.1 1804004 1804825 R KEGG: ssn:SSO_1662 3.0e-59 putative N-hydroxyarylamine O-acetyltransferase K00675; COG: COG2162 Arylamine N-acetyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1804004..1804825) Cronobacter sakazakii ATCC BAA-894 5550149 YP_001437961.1 CDS ESA_01871 NC_009778.1 1805300 1805809 D COG: COG3685 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 1805300..1805809 Cronobacter sakazakii ATCC BAA-894 5549779 YP_001437962.1 CDS ESA_01872 NC_009778.1 1805883 1806788 D KEGG: reu:Reut_B4409 4.9e-107 catalase K07217; COG: COG3546 Mn-containing catalase; Psort location: cytoplasmic, score: 23; hypothetical protein 1805883..1806788 Cronobacter sakazakii ATCC BAA-894 5549560 YP_001437963.1 CDS ESA_01873 NC_009778.1 1806833 1807123 R 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase complement(1806833..1807123) Cronobacter sakazakii ATCC BAA-894 5550304 YP_001437964.1 CDS ESA_01874 NC_009778.1 1807325 1807969 D KEGG: eci:UTI89_C0578 5.6e-51 nfnB; oxygen-insensitive NAD(P)H nitroreductase K00357; COG: COG0778 Nitroreductase; Psort location: golgi, score: 9; hypothetical protein 1807325..1807969 Cronobacter sakazakii ATCC BAA-894 5549591 YP_001437965.1 CDS ESA_01875 NC_009778.1 1808021 1809148 R KEGG: bur:Bcep18194_C7532 5.9e-95 beta-lactamase K01467; COG: COG1680 Beta-lactamase class C and other penicillin binding proteins; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1808021..1809148) Cronobacter sakazakii ATCC BAA-894 5550231 YP_001437966.1 CDS ESA_01877 NC_009778.1 1809486 1811069 R COG: NOG38279 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(1809486..1811069) Cronobacter sakazakii ATCC BAA-894 5550172 YP_001437967.1 CDS ESA_01876 NC_009778.1 1809510 1810967 D KEGG: eci:UTI89_C0120 9.8e-86 aroP; aromatic amino acid transport protein AroP K03293; COG: COG1113 Gamma-aminobutyrate permease and related permeases; Psort location: plasma membrane, score: 23; hypothetical protein 1809510..1810967 Cronobacter sakazakii ATCC BAA-894 5550169 YP_001437968.1 CDS ESA_01878 NC_009778.1 1811090 1812136 D COG: NOG10065 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1811090..1812136 Cronobacter sakazakii ATCC BAA-894 5549608 YP_001437969.1 CDS ESA_01879 NC_009778.1 1812312 1813310 D COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1812312..1813310 Cronobacter sakazakii ATCC BAA-894 5550166 YP_001437970.1 CDS ESA_01882 NC_009778.1 1813312 1814244 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1813312..1814244) Cronobacter sakazakii ATCC BAA-894 5550164 YP_001437971.1 CDS ESA_01880 NC_009778.1 1813339 1814223 D KEGG: pst:PSPTO_5198 3.2e-119 dioxygenase, TauD/TfdA family K03119; COG: COG2175 Probable taurine catabolism dioxygenase; Psort location: cytoplasmic, score: 23; hypothetical protein 1813339..1814223 Cronobacter sakazakii ATCC BAA-894 5549480 YP_001437972.1 CDS ESA_01881 NC_009778.1 1814235 1815074 D KEGG: reh:H16_B2218 1.3e-92 ABC-type transporter, ATPase component: NitT family; COG: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 1814235..1815074 Cronobacter sakazakii ATCC BAA-894 5549679 YP_001437973.1 CDS ESA_01883 NC_009778.1 1815034 1815900 D KEGG: lwe:lwe1444 2.1e-13 opuCB; glycine betaine/L-proline ABC transporter, permease protein; COG: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1815034..1815900 Cronobacter sakazakii ATCC BAA-894 5550189 YP_001437974.1 CDS ESA_01884 NC_009778.1 1815930 1816967 R COG: COG3391 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1815930..1816967) Cronobacter sakazakii ATCC BAA-894 5549722 YP_001437975.1 CDS ESA_01885 NC_009778.1 1817265 1819382 D COG: COG1629 Outer membrane receptor proteins, mostly Fe transport; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1817265..1819382 Cronobacter sakazakii ATCC BAA-894 5549659 YP_001437976.1 CDS ESA_01886 NC_009778.1 1819437 1819724 R COG: COG3093 Plasmid maintenance system antidote protein; Psort location: mitochondrial, score: 23; hypothetical protein complement(1819437..1819724) Cronobacter sakazakii ATCC BAA-894 5550183 YP_001437977.1 CDS ESA_01887 NC_009778.1 1819724 1820002 R COG: COG3549 Plasmid maintenance system killer protein; Psort location: mitochondrial, score: 23; hypothetical protein complement(1819724..1820002) Cronobacter sakazakii ATCC BAA-894 5550291 YP_001437978.1 CDS ESA_01888 NC_009778.1 1820146 1821906 D KEGG: ret:RHE_CH02260 2.5e-103 putative trehalose synthase (glycosyl hydrolase) protein K05343; COG: COG0366 Glycosidases; Psort location: cytoplasmic, score: 23; hypothetical protein 1820146..1821906 Cronobacter sakazakii ATCC BAA-894 5548544 YP_001437979.1 CDS ESA_01889 NC_009778.1 1821908 1822894 R KEGG: noc:Noc_0472 3.7e-77 short chain dehydrogenase K00059; COG: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1821908..1822894) Cronobacter sakazakii ATCC BAA-894 5548534 YP_001437980.1 CDS ESA_01890 NC_009778.1 1823003 1824940 R KEGG: vch:VCA0709 2.1e-08 torS; sensor protein TorS K07647; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1823003..1824940) Cronobacter sakazakii ATCC BAA-894 5548555 YP_001437981.1 CDS ESA_01891 NC_009778.1 1825153 1825332 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1825153..1825332) Cronobacter sakazakii ATCC BAA-894 5548596 YP_001437982.1 CDS ESA_01892 NC_009778.1 1825442 1826101 R KEGG: msm:MSMEG_3400 2.5e-11 glutamyl-tRNA(Gln) amidotransferase subunit A K01957; COG: COG1802 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1825442..1826101) Cronobacter sakazakii ATCC BAA-894 5548595 YP_001437983.1 CDS ESA_01893 NC_009778.1 1826279 1827772 D KEGG: shn:Shewana3_2650 2.9e-29 acetate kinase K00925; COG: COG0747 ABC-type dipeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1826279..1827772 Cronobacter sakazakii ATCC BAA-894 5548539 YP_001437984.1 CDS ESA_01894 NC_009778.1 1827769 1828614 D KEGG: baa:BA_0884 1.5e-06 binding-protein-dependent transport systems inner membrane component K00294; COG: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1827769..1828614 Cronobacter sakazakii ATCC BAA-894 5548889 YP_001437985.1 CDS ESA_01895 NC_009778.1 1828614 1829528 D KEGG: rha:RHA1_ro09047 4.5e-49 ABC peptide transporter, permease component K02033; COG: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1828614..1829528 Cronobacter sakazakii ATCC BAA-894 5549072 YP_001437986.1 CDS ESA_01896 NC_009778.1 1829525 1830871 D KEGG: gox:GOX2239 1.4e-16 hypothetical protein K01436; COG: COG0624 AcetylorniTHIne deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: cytoplasmic, score: 23; hypothetical protein 1829525..1830871 Cronobacter sakazakii ATCC BAA-894 5549252 YP_001437987.1 CDS ESA_01897 NC_009778.1 1830890 1831867 D KEGG: sdn:Sden_0589 3.1e-34 orniTHIne cyclodeaminase K01750; COG: COG2423 Predicted orniTHIne cyclodeaminase, mu-crystallin homolog; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1830890..1831867 Cronobacter sakazakii ATCC BAA-894 5549001 YP_001437988.1 CDS ESA_01898 NC_009778.1 1831864 1833213 R KEGG: rru:Rru_A2011 6.2e-100 ABC transporter component K06020:K06021; COG: COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1831864..1833213) Cronobacter sakazakii ATCC BAA-894 5549100 YP_001437989.1 CDS ESA_01899 NC_009778.1 1833220 1833468 D Psort location: cytoplasmic, score: 23; hypothetical protein 1833220..1833468 Cronobacter sakazakii ATCC BAA-894 5549166 YP_001437990.1 CDS ESA_01900 NC_009778.1 1833553 1834641 R KEGG: ece:Z2270 6.4e-153 yncB; putative oxidoreductase; COG: COG2130 Putative NADP-dependent oxidoreductases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1833553..1834641) Cronobacter sakazakii ATCC BAA-894 5549190 YP_001437991.1 CDS ESA_01901 NC_009778.1 1834643 1835218 R KEGG: psp:PSPPH_2917 5.7e-10 DNA-binding protein K00517; COG: COG1396 Predicted transcriptional regulators; Psort location: nuclear, score: 23; hypothetical protein complement(1834643..1835218) Cronobacter sakazakii ATCC BAA-894 5549057 YP_001437992.1 CDS ESA_01902 NC_009778.1 1835257 1835775 D KEGG: ecj:JW5233 8.8e-69 yncA; predicted acyltransferase with acyl-CoA N-acyltransferase domain K03823; COG: COG1247 Sortase and related acyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 1835257..1835775 Cronobacter sakazakii ATCC BAA-894 5549161 YP_001437993.1 CDS ESA_01903 NC_009778.1 1835772 1836221 D COG: COG3238 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1835772..1836221 Cronobacter sakazakii ATCC BAA-894 5549322 YP_001437994.1 CDS ESA_01904 NC_009778.1 1836225 1837109 R KEGG: xcc:XCC0308 6.6e-80 dehydrogenase K00100; COG: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1836225..1837109) Cronobacter sakazakii ATCC BAA-894 5549157 YP_001437995.1 CDS ESA_01905 NC_009778.1 1837126 1837371 R COG: NOG13890 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(1837126..1837371) Cronobacter sakazakii ATCC BAA-894 5549145 YP_001437996.1 CDS ESA_01906 NC_009778.1 1837419 1839014 R KEGG: shn:Shewana3_2650 5.2e-119 acetate kinase K00925; COG: COG0747 ABC-type dipeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1837419..1839014) Cronobacter sakazakii ATCC BAA-894 5549130 YP_001437997.1 CDS ESA_01907 NC_009778.1 1839328 1840749 D KEGG: cal:orf19.4334 1.2e-10 hypothetical protein K00960; COG: NOG35976 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 1839328..1840749 Cronobacter sakazakii ATCC BAA-894 5549184 YP_001437998.1 CDS ESA_01908 NC_009778.1 1840753 1843740 D COG: COG4457 Uncharacterized protein conserved in bacteria, putative virulence factor; Psort location: cytoplasmic, score: 23; hypothetical protein 1840753..1843740 Cronobacter sakazakii ATCC BAA-894 5549022 YP_001437999.1 CDS ESA_01909 NC_009778.1 1843737 1845935 D COG: COG4458 Uncharacterized protein conserved in bacteria, putative virulence factor; Psort location: cytoplasmic, score: 23; hypothetical protein 1843737..1845935 Cronobacter sakazakii ATCC BAA-894 5549077 YP_001438000.1 CDS ESA_01910 NC_009778.1 1845948 1846208 D Psort location: mitochondrial, score: 23; hypothetical protein 1845948..1846208 Cronobacter sakazakii ATCC BAA-894 5549110 YP_001438001.1 CDS ESA_01912 NC_009778.1 1846015 1846455 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1846015..1846455) Cronobacter sakazakii ATCC BAA-894 5548960 YP_001438002.1 CDS ESA_01911 NC_009778.1 1846237 1846728 D KEGG: cal:orf19.2606 0.0029 HDA1; histone deacetylase A; COG: NOG12157 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1846237..1846728 Cronobacter sakazakii ATCC BAA-894 5549210 YP_001438003.1 CDS ESA_01913 NC_009778.1 1846775 1847902 R KEGG: hma:rrnAC0265 9.6e-05 apl; AP-endonuclease/AP-lyase K01151:K01741; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1846775..1847902) Cronobacter sakazakii ATCC BAA-894 5549185 YP_001438004.1 CDS ESA_01914 NC_009778.1 1848064 1849602 D KEGG: cvi:CV1579 7.6e-07 probable two-component hybrid sensor and regulator; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1848064..1849602 Cronobacter sakazakii ATCC BAA-894 5549207 YP_001438005.1 CDS ESA_01915 NC_009778.1 1849654 1851009 R KEGG: ava:Ava_3999 2.9e-33 phytase K01083; COG: COG4222 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1849654..1851009) Cronobacter sakazakii ATCC BAA-894 5552335 YP_001438006.1 CDS ESA_01916 NC_009778.1 1851110 1851961 R KEGG: mba:Mbar_A2589 1.7e-10 heterodisulfate reductase, subunit A K03388; COG: COG1145 Ferredoxin; Psort location: mitochondrial, score: 23; hypothetical protein complement(1851110..1851961) Cronobacter sakazakii ATCC BAA-894 5549214 YP_001438007.1 CDS ESA_01917 NC_009778.1 1851961 1852797 R KEGG: dsy:DSY0355 2.7e-28 dmsC; putative anaerobic DMSO reductase chain C anchor subunit K00369; COG: COG3302 DMSO reductase anchor subunit; Psort location: plasma membrane, score: 23; hypothetical protein complement(1851961..1852797) Cronobacter sakazakii ATCC BAA-894 5549336 YP_001438008.1 CDS ESA_01918 NC_009778.1 1852790 1853419 R KEGG: dsy:DSY0356 2.9e-61 dmsB; putative anaerobic DMSO reductase chain B iron-sulfur subunit K00369; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: nuclear, score: 23; hypothetical protein complement(1852790..1853419) Cronobacter sakazakii ATCC BAA-894 5549222 YP_001438009.1 CDS ESA_01919 NC_009778.1 1853406 1855790 R KEGG: dsy:DSY0357 1.0e-239 dmsA; putative anaerobic DMSO reductase chain A precursor K00369; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1853406..1855790) Cronobacter sakazakii ATCC BAA-894 5549337 YP_001438010.1 CDS ESA_01920 NC_009778.1 1855963 1857159 R KEGG: reh:H16_A1591 1.0e-90 membrane-bound alcohol dehydrogenase,cytochromec subunit precursor K00119; COG: COG2010 Cytochrome c, mono- and diheme variants; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1855963..1857159) Cronobacter sakazakii ATCC BAA-894 5549405 YP_001438011.1 CDS ESA_01921 NC_009778.1 1857156 1859054 R KEGG: mmu:17161 0.00085 Maoa; monoamine oxidase A K00274; COG: NOG06242 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1857156..1859054) Cronobacter sakazakii ATCC BAA-894 5549226 YP_001438012.1 CDS ESA_01922 NC_009778.1 1859157 1859357 R Psort location: nuclear, score: 23; hypothetical protein complement(1859157..1859357) Cronobacter sakazakii ATCC BAA-894 5549311 YP_001438013.1 CDS ESA_01923 NC_009778.1 1859413 1859751 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1859413..1859751) Cronobacter sakazakii ATCC BAA-894 5549269 YP_001438014.1 CDS ESA_01924 NC_009778.1 1859878 1860063 R KEGG: btk:BT9727_1901 0.0021 acetyltransferase, GNAT family K00680; Psort location: mitochondrial, score: 23; hypothetical protein complement(1859878..1860063) Cronobacter sakazakii ATCC BAA-894 5551271 YP_001438015.1 CDS ESA_01925 NC_009778.1 1859975 1860298 R KEGG: bur:Bcep18194_A5735 0.00031 GCN5-related N-acetyltransferase K00657; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1859975..1860298) Cronobacter sakazakii ATCC BAA-894 5549312 YP_001438016.1 CDS ESA_01926 NC_009778.1 1860295 1860801 R KEGG: reh:H16_B1292 1.7e-10 phnT; acetyltransferase (GNAT) family K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: mitochondrial, score: 23; hypothetical protein complement(1860295..1860801) Cronobacter sakazakii ATCC BAA-894 5552359 YP_001438017.1 CDS ESA_01927 NC_009778.1 1861006 1861485 D Psort location: nuclear, score: 23; hypothetical protein 1861006..1861485 Cronobacter sakazakii ATCC BAA-894 5549403 YP_001438018.1 CDS ESA_01928 NC_009778.1 1861604 1863031 R catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase complement(1861604..1863031) Cronobacter sakazakii ATCC BAA-894 5549238 YP_001438019.1 CDS ESA_01929 NC_009778.1 1863049 1863855 R KEGG: pac:PPA0505 3.4e-10 ABC transporter, putative molybdenum transport system K02017:K02018; COG: COG1177 ABC-type spermidine/putrescine transport system, permease component II; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1863049..1863855) Cronobacter sakazakii ATCC BAA-894 5549179 YP_001438020.1 CDS ESA_01931 NC_009778.1 1863845 1864789 R KEGG: cdi:DIP0495 2.3e-09 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; COG: COG1176 ABC-type spermidine/putrescine transport system, permease component I; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1863845..1864789) Cronobacter sakazakii ATCC BAA-894 5549234 YP_001438021.1 CDS ESA_01930 NC_009778.1 1864782 1865834 D Psort location: cytoplasmic, score: 23; hypothetical protein 1864782..1865834 Cronobacter sakazakii ATCC BAA-894 5549266 YP_001438022.1 CDS ESA_01932 NC_009778.1 1864791 1865804 R KEGG: ssn:SSO_1696 1.6e-131 putative ATP-binding component of a transport system K02052; COG: COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1864791..1865804) Cronobacter sakazakii ATCC BAA-894 5549393 YP_001438023.1 CDS ESA_01933 NC_009778.1 1865818 1866963 R COG: COG0687 Spermidine/putrescine-binding periplasmic protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1865818..1866963) Cronobacter sakazakii ATCC BAA-894 5549357 YP_001438024.1 CDS ESA_01934 NC_009778.1 1867353 1868774 R KEGG: eci:UTI89_C1658 5.1e-192 ydcR; hypothetical protein YdcR K00811; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1867353..1868774) Cronobacter sakazakii ATCC BAA-894 5549387 YP_001438025.1 CDS ESA_01935 NC_009778.1 1868972 1870381 D KEGG: stm:STM0360 8.5e-222 cytochrome BD2 subunit I K00425; COG: COG1271 Cytochrome bd-type quinol oxidase, subunit 1; Psort location: plasma membrane, score: 23; hypothetical protein 1868972..1870381 Cronobacter sakazakii ATCC BAA-894 5549271 YP_001438026.1 CDS ESA_01936 NC_009778.1 1870381 1871391 D KEGG: sec:SC0402 1.6e-147 cydB; cytochrome BD2 subunit II K00426; COG: COG1294 Cytochrome bd-type quinol oxidase, subunit 2; Psort location: plasma membrane, score: 23; hypothetical protein 1870381..1871391 Cronobacter sakazakii ATCC BAA-894 5549342 YP_001438027.1 CDS ESA_01937 NC_009778.1 1871391 1871528 D COG: NOG22122 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1871391..1871528 Cronobacter sakazakii ATCC BAA-894 5549286 YP_001438028.1 CDS ESA_01939 NC_009778.1 1871514 1871669 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1871514..1871669) Cronobacter sakazakii ATCC BAA-894 5549335 YP_001438029.1 CDS ESA_01938 NC_009778.1 1871652 1872221 D COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1871652..1872221 Cronobacter sakazakii ATCC BAA-894 5549398 YP_001438030.1 CDS ESA_01940 NC_009778.1 1872226 1872555 D KEGG: syn:slr0813 0.0012 ceramide glucosyltransferase K00720; COG: COG2076 Membrane transporters of cations and cationic drugs; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1872226..1872555 Cronobacter sakazakii ATCC BAA-894 5549258 YP_001438031.1 CDS ESA_01941 NC_009778.1 1872962 1874365 D KEGG: eci:UTI89_C4210 8.4e-80 yicJ; hypothetical symporter YicJ K03292; COG: COG2211 Na+/melibiose symporter and related transporters; Psort location: plasma membrane, score: 23; hypothetical protein 1872962..1874365 Cronobacter sakazakii ATCC BAA-894 5549287 YP_001438032.1 CDS ESA_01942 NC_009778.1 1874378 1875898 D KEGG: sma:SAV5743 6.1e-132 abfA; putative alpha-L-arabinofuranosidase K01209; COG: COG3534 Alpha-L-arabinofuranosidase; Psort location: cytoplasmic, score: 23; hypothetical protein 1874378..1875898 Cronobacter sakazakii ATCC BAA-894 5549415 YP_001438033.1 CDS ESA_01943 NC_009778.1 1876012 1877199 D COG: NOG06288 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1876012..1877199 Cronobacter sakazakii ATCC BAA-894 5549278 YP_001438034.1 CDS ESA_01944 NC_009778.1 1877346 1878962 D KEGG: shn:Shewana3_2650 8.5e-11 acetate kinase K00925; COG: COG0747 ABC-type dipeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1877346..1878962 Cronobacter sakazakii ATCC BAA-894 5549274 YP_001438035.1 CDS ESA_01945 NC_009778.1 1878962 1879906 D KEGG: rha:RHA1_ro09047 7.6e-47 ABC peptide transporter, permease component K02033; COG: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1878962..1879906 Cronobacter sakazakii ATCC BAA-894 5549275 YP_001438036.1 CDS ESA_01946 NC_009778.1 1879906 1880754 D KEGG: lwe:lwe1444 0.00066 opuCB; glycine betaine/L-proline ABC transporter, permease protein; COG: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1879906..1880754 Cronobacter sakazakii ATCC BAA-894 5549254 YP_001438037.1 CDS ESA_01947 NC_009778.1 1880751 1882364 D KEGG: fal:FRAAL3863 3.6e-120 putative ABC transport protein, ATPase component; COG: COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1880751..1882364 Cronobacter sakazakii ATCC BAA-894 5549262 YP_001438038.1 CDS ESA_01948 NC_009778.1 1882361 1883410 D KEGG: fal:FRAAL4791 9.5e-56 putative monooxigenase; COG: COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; Psort location: cytoplasmic, score: 23; hypothetical protein 1882361..1883410 Cronobacter sakazakii ATCC BAA-894 5550053 YP_001438039.1 CDS ESA_01949 NC_009778.1 1883407 1884501 D KEGG: azo:azo2506 1.6e-05 cmd; 4-carboxymuconolactone decarboxylase K01607; COG: COG2128 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 1883407..1884501 Cronobacter sakazakii ATCC BAA-894 5549228 YP_001438040.1 CDS ESA_01950 NC_009778.1 1884529 1885347 R KEGG: ecj:JW0806 4.2e-94 ybiV; predicted hydrolase K07757; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1884529..1885347) Cronobacter sakazakii ATCC BAA-894 5549911 YP_001438041.1 CDS ESA_01951 NC_009778.1 1885548 1886111 R COG: COG2840 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(1885548..1886111) Cronobacter sakazakii ATCC BAA-894 5549930 YP_001438042.1 CDS ESA_01952 NC_009778.1 1886159 1886311 R Psort location: nuclear, score: 23; hypothetical protein complement(1886159..1886311) Cronobacter sakazakii ATCC BAA-894 5549923 YP_001438043.1 CDS ESA_01953 NC_009778.1 1886711 1887226 D KEGG: ece:Z2432 5.5e-76 ogt; O-6-alkylguanine-DNA/cysteine-protein methyltransferase K00567; COG: COG0350 Methylated DNA-protein cysteine methyltransferase; Psort location: cytoplasmic, score: 23; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1886711..1887226 Cronobacter sakazakii ATCC BAA-894 5549924 YP_001438044.1 CDS ESA_01954 NC_009778.1 1887404 1888156 D Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1887404..1888156 Cronobacter sakazakii ATCC BAA-894 5549931 YP_001438045.1 CDS ESA_01955 NC_009778.1 1888293 1889249 D with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1888293..1889249 Cronobacter sakazakii ATCC BAA-894 5549940 YP_001438046.1 CDS pntB NC_009778.1 1889365 1890753 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1889365..1890753) Cronobacter sakazakii ATCC BAA-894 5549959 YP_001438047.1 CDS pntA NC_009778.1 1890764 1892314 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1890764..1892314) Cronobacter sakazakii ATCC BAA-894 5549946 YP_001438048.1 CDS ESA_01958 NC_009778.1 1892825 1893769 D COG: NOG06063 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1892825..1893769 Cronobacter sakazakii ATCC BAA-894 5550012 YP_001438049.1 CDS ESA_01959 NC_009778.1 1893954 1895336 D KEGG: eci:UTI89_C0120 2.1e-08 aroP; aromatic amino acid transport protein AroP K03293; COG: COG0531 Amino acid transporters; Psort location: plasma membrane, score: 23; hypothetical protein 1893954..1895336 Cronobacter sakazakii ATCC BAA-894 5549980 YP_001438050.1 CDS ESA_01961 NC_009778.1 1896244 1896894 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1896244..1896894 Cronobacter sakazakii ATCC BAA-894 5550050 YP_001438051.1 CDS ESA_01962 NC_009778.1 1896930 1897682 R KEGG: bur:Bcep18194_C7235 4.9e-52 short-chain dehydrogenase/reductase SDR K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein complement(1896930..1897682) Cronobacter sakazakii ATCC BAA-894 5550056 YP_001438052.1 CDS ESA_01963 NC_009778.1 1897794 1898699 D KEGG: shn:Shewana3_3435 6.5e-08 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1897794..1898699 Cronobacter sakazakii ATCC BAA-894 5550117 YP_001438053.1 CDS ESA_01964 NC_009778.1 1898726 1900018 D KEGG: sty:STY1651 2.7e-177 rstB; two component sensor kinase K07639; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; sensor protein RstB 1898726..1900018 Cronobacter sakazakii ATCC BAA-894 5550136 YP_001438054.1 CDS ESA_01965 NC_009778.1 1900512 1901441 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1900512..1901441 Cronobacter sakazakii ATCC BAA-894 5550143 YP_001438055.1 CDS fumC NC_009778.1 1901442 1902839 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1901442..1902839) Cronobacter sakazakii ATCC BAA-894 5550144 YP_001438056.1 CDS ESA_01967 NC_009778.1 1902995 1904641 R KEGG: spt:SPA1387 4.8e-274 fumA; Fumarate hydratase class I, aerobic K01676; COG: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1902995..1904641) Cronobacter sakazakii ATCC BAA-894 5550137 YP_001438057.1 CDS ESA_01968 NC_009778.1 1904847 1906025 D KEGG: stm:STM1467 3.4e-170 manA; mannose-6-phosphate isomerase K01809; COG: COG1482 Phosphomannose isomerase; Psort location: cytoplasmic, score: 23; hypothetical protein 1904847..1906025 Cronobacter sakazakii ATCC BAA-894 5550142 YP_001438058.1 CDS ESA_01969 NC_009778.1 1906125 1907678 D COG: COG5339 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1906125..1907678 Cronobacter sakazakii ATCC BAA-894 5550151 YP_001438059.1 CDS ESA_01970 NC_009778.1 1907755 1908267 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1907755..1908267) Cronobacter sakazakii ATCC BAA-894 5550065 YP_001438060.1 CDS ESA_01971 NC_009778.1 1908302 1908823 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1908302..1908823) Cronobacter sakazakii ATCC BAA-894 5550107 YP_001438061.1 CDS ESA_01972 NC_009778.1 1908937 1909467 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1908937..1909467) Cronobacter sakazakii ATCC BAA-894 5550108 YP_001438062.1 CDS ESA_01973 NC_009778.1 1909493 1910461 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1909493..1910461) Cronobacter sakazakii ATCC BAA-894 5550038 YP_001438063.1 CDS ESA_01974 NC_009778.1 1910461 1912848 R COG: COG3188 P pilus assembly protein, porin PapC; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1910461..1912848) Cronobacter sakazakii ATCC BAA-894 5549953 YP_001438064.1 CDS ESA_01975 NC_009778.1 1913044 1913721 R COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1913044..1913721) Cronobacter sakazakii ATCC BAA-894 5550020 YP_001438065.1 CDS ESA_01976 NC_009778.1 1913789 1914319 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(1913789..1914319) Cronobacter sakazakii ATCC BAA-894 5552474 YP_001438066.1 CDS ESA_01977 NC_009778.1 1915398 1916426 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1915398..1916426) Cronobacter sakazakii ATCC BAA-894 5551814 YP_001438067.1 CDS ESA_01978 NC_009778.1 1916601 1918190 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1916601..1918190 Cronobacter sakazakii ATCC BAA-894 5552310 YP_001438068.1 CDS ESA_01979 NC_009778.1 1918204 1919373 D KEGG: ece:Z2627 2.3e-155 malY; enzyme that may degrade or block biosynthesis of endogenous mal inducer, probably aminotrasferase K01760; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities; Psort location: cytoplasmic, score: 23; hypothetical protein 1918204..1919373 Cronobacter sakazakii ATCC BAA-894 5549949 YP_001438069.1 CDS ESA_01980 NC_009778.1 1919449 1920480 D KEGG: stt:t1331 2.1e-147 add; adenosine deaminase K01488; COG: COG1816 Adenosine deaminase; Psort location: cytoplasmic, score: 23; hypothetical protein 1919449..1920480 Cronobacter sakazakii ATCC BAA-894 5552489 YP_001438070.1 CDS ESA_01981 NC_009778.1 1920495 1921493 R COG: COG0385 Predicted Na+-dependent transporter; Psort location: plasma membrane, score: 23; hypothetical protein complement(1920495..1921493) Cronobacter sakazakii ATCC BAA-894 5549708 YP_001438071.1 CDS ESA_01982 NC_009778.1 1921509 1921640 D Psort location: nuclear, score: 23; hypothetical protein 1921509..1921640 Cronobacter sakazakii ATCC BAA-894 5552495 YP_001438072.1 CDS ESA_01983 NC_009778.1 1921644 1922687 R KEGG: eci:UTI89_C1812 6.9e-156 ydgJ; hypothetical oxidoreductase YdgJ; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: cytoplasmic, score: 23; putative oxidoreductase complement(1921644..1922687) Cronobacter sakazakii ATCC BAA-894 5552377 YP_001438073.1 CDS ESA_01984 NC_009778.1 1923321 1923536 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1923321..1923536 Cronobacter sakazakii ATCC BAA-894 5549732 YP_001438074.1 CDS ESA_01985 NC_009778.1 1923631 1924074 D COG: NOG08686 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1923631..1924074 Cronobacter sakazakii ATCC BAA-894 5549720 YP_001438075.1 CDS ESA_01986 NC_009778.1 1924149 1924730 D KEGG: vfi:VF0935 1.9e-75 Na(+)-translocating NADH-quinone reductase subunit E K03617; COG: COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA; Psort location: plasma membrane, score: 23; hypothetical protein 1924149..1924730 Cronobacter sakazakii ATCC BAA-894 5551780 YP_001438076.1 CDS ESA_01987 NC_009778.1 1924730 1925308 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1924730..1925308 Cronobacter sakazakii ATCC BAA-894 5552304 YP_001438077.1 CDS ESA_01988 NC_009778.1 1925301 1927631 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1925301..1927631 Cronobacter sakazakii ATCC BAA-894 5551757 YP_001438078.1 CDS rnfD NC_009778.1 1927632 1928684 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1927632..1928684 Cronobacter sakazakii ATCC BAA-894 5549739 YP_001438079.1 CDS ESA_01990 NC_009778.1 1928694 1929320 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1928694..1929320 Cronobacter sakazakii ATCC BAA-894 5549734 YP_001438080.1 CDS ESA_01991 NC_009778.1 1929317 1930003 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1929317..1930003 Cronobacter sakazakii ATCC BAA-894 5549698 YP_001438081.1 CDS ESA_01992 NC_009778.1 1930000 1930635 D KEGG: stm:STM1453 9.8e-102 nth; endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase K07457; COG: COG0177 Predicted EndoIII-related endonuclease; Psort location: cytoplasmic, score: 23; hypothetical protein 1930000..1930635 Cronobacter sakazakii ATCC BAA-894 5552371 YP_001438082.1 CDS tppB NC_009778.1 1931200 1932726 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1931200..1932726 Cronobacter sakazakii ATCC BAA-894 5549818 YP_001438083.1 CDS ESA_01994 NC_009778.1 1932835 1933443 D KEGG: spt:SPA1402 6.5e-73 gst; glutathione S-transferase K00799; COG: COG0625 glutathione S-transferase; Psort location: cytoplasmic, score: 23; glutathionine S-transferase 1932835..1933443 Cronobacter sakazakii ATCC BAA-894 5552458 YP_001438084.1 CDS ESA_01995 NC_009778.1 1933484 1934344 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1933484..1934344) Cronobacter sakazakii ATCC BAA-894 5549686 YP_001438085.1 CDS ESA_01996 NC_009778.1 1934419 1935705 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1934419..1935705) Cronobacter sakazakii ATCC BAA-894 5550690 YP_001438086.1 CDS ESA_01997 NC_009778.1 1935832 1936488 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1935832..1936488) Cronobacter sakazakii ATCC BAA-894 5552233 YP_001438087.1 CDS ESA_01998 NC_009778.1 1936545 1936868 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1936545..1936868) Cronobacter sakazakii ATCC BAA-894 5550681 YP_001438088.1 CDS anmK NC_009778.1 1936927 1938081 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1936927..1938081) Cronobacter sakazakii ATCC BAA-894 5552485 YP_001438089.1 CDS ESA_02000 NC_009778.1 1938340 1938807 D COG: COG3133 Outer membrane lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1938340..1938807 Cronobacter sakazakii ATCC BAA-894 5552404 YP_001438090.1 CDS ESA_02001 NC_009778.1 1938926 1939366 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1938926..1939366) Cronobacter sakazakii ATCC BAA-894 5549948 YP_001438091.1 CDS ESA_02002 NC_009778.1 1939541 1939777 D COG: NOG13888 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1939541..1939777 Cronobacter sakazakii ATCC BAA-894 5552320 YP_001438092.1 CDS ESA_02003 NC_009778.1 1939782 1940639 D COG: COG1566 Multidrug resistance efflux pump; Psort location: mitochondrial, score: 23; hypothetical protein 1939782..1940639 Cronobacter sakazakii ATCC BAA-894 5551683 YP_001438093.1 CDS ESA_02004 NC_009778.1 1940649 1942682 D COG: COG1289 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein 1940649..1942682 Cronobacter sakazakii ATCC BAA-894 5550031 YP_001438094.1 CDS ESA_02005 NC_009778.1 1942675 1943193 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1942675..1943193) Cronobacter sakazakii ATCC BAA-894 5549888 YP_001438095.1 CDS ESA_02006 NC_009778.1 1943273 1944169 R KEGG: ecc:c2039 5.0e-130 ydhF; hypothetical oxidoreductase YdhF; COG: COG4989 Predicted oxidoreductase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1943273..1944169) Cronobacter sakazakii ATCC BAA-894 5549759 YP_001438096.1 CDS ESA_02007 NC_009778.1 1944222 1944374 R COG: COG3313 Predicted Fe-S protein; Psort location: nuclear, score: 23; hypothetical protein complement(1944222..1944374) Cronobacter sakazakii ATCC BAA-894 5552063 YP_001438097.1 CDS ESA_02008 NC_009778.1 1944666 1946294 D with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein 1944666..1946294 Cronobacter sakazakii ATCC BAA-894 5552148 YP_001438098.1 CDS ESA_02009 NC_009778.1 1946359 1946940 D KEGG: bpm:BURPS1710b_A2293 3.8e-36 TetR-family regulatory protein K00356; COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1946359..1946940 Cronobacter sakazakii ATCC BAA-894 5549750 YP_001438099.1 CDS ESA_02010 NC_009778.1 1947015 1948112 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1947015..1948112 Cronobacter sakazakii ATCC BAA-894 5549770 YP_001438100.1 CDS ESA_02011 NC_009778.1 1948204 1948611 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1948204..1948611 Cronobacter sakazakii ATCC BAA-894 5551852 YP_001438101.1 CDS ESA_02012 NC_009778.1 1948707 1949378 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1948707..1949378 Cronobacter sakazakii ATCC BAA-894 5549774 YP_001438102.1 CDS ESA_02013 NC_009778.1 1949449 1949796 R KEGG: ama:AM1083 1.2e-07 grxC1; glutaredoxin 3 K03676; COG: COG0278 Glutaredoxin-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1949449..1949796) Cronobacter sakazakii ATCC BAA-894 5549789 YP_001438103.1 CDS ESA_02014 NC_009778.1 1949793 1949927 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1949793..1949927) Cronobacter sakazakii ATCC BAA-894 5549688 YP_001438104.1 CDS ESA_02016 NC_009778.1 1950123 1950578 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1950123..1950578) Cronobacter sakazakii ATCC BAA-894 5549735 YP_001438105.1 CDS ESA_02015 NC_009778.1 1950577 1950960 D KEGG: ssn:SSO_1501 1.4e-61 ydhO; putative lipoprotein K01183; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: cytoplasmic, score: 23; hypothetical protein 1950577..1950960 Cronobacter sakazakii ATCC BAA-894 5549809 YP_001438106.1 CDS ESA_02017 NC_009778.1 1951029 1952195 R KEGG: tbd:Tbd_2790 0.0027 dsbD; THIol:disulfide interchange protein DsbD K04084; COG: COG2814 Arabinose efflux permease; Psort location: plasma membrane, score: 23; hypothetical protein complement(1951029..1952195) Cronobacter sakazakii ATCC BAA-894 5549758 YP_001438107.1 CDS ESA_02018 NC_009778.1 1952458 1952598 R Psort location: cytoplasmic, score: 23; membrane protein complement(1952458..1952598) Cronobacter sakazakii ATCC BAA-894 5549827 YP_001438108.1 CDS ESA_02019 NC_009778.1 1952839 1953864 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1952839..1953864 Cronobacter sakazakii ATCC BAA-894 5549824 YP_001438109.1 CDS ESA_02020 NC_009778.1 1953882 1954793 R KEGG: shn:Shewana3_3435 0.0012 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; putative DNA-binding transcriptional regulator complement(1953882..1954793) Cronobacter sakazakii ATCC BAA-894 5551996 YP_001438110.1 CDS ESA_02021 NC_009778.1 1954905 1956080 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1954905..1956080 Cronobacter sakazakii ATCC BAA-894 5549837 YP_001438111.1 CDS ESA_02022 NC_009778.1 1956225 1957517 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 1956225..1957517 Cronobacter sakazakii ATCC BAA-894 5549816 YP_001438112.1 CDS ESA_02023 NC_009778.1 1957712 1959031 D KEGG: eca:ECA2488 2.7e-186 PTS system, cellobiose-specific IIc component K02761; COG: COG1455 Phosphotransferase system cellobiose-specific component IIC; Psort location: plasma membrane, score: 23; hypothetical protein 1957712..1959031 Cronobacter sakazakii ATCC BAA-894 5549878 YP_001438113.1 CDS ESA_02024 NC_009778.1 1959073 1960470 D KEGG: eca:ECA4407 2.5e-213 putative glycosyl hydrolase K05350; COG: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Psort location: cytoplasmic, score: 23; hypothetical protein 1959073..1960470 Cronobacter sakazakii ATCC BAA-894 5549814 YP_001438114.1 CDS ESA_02025 NC_009778.1 1960515 1961435 D KEGG: efa:EF1922 0.0089 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 1960515..1961435 Cronobacter sakazakii ATCC BAA-894 5549869 YP_001438115.1 CDS ESA_02026 NC_009778.1 1961452 1962102 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1961452..1962102) Cronobacter sakazakii ATCC BAA-894 5552124 YP_001438116.1 CDS ESA_02027 NC_009778.1 1962339 1963712 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1962339..1963712 Cronobacter sakazakii ATCC BAA-894 5549796 YP_001438117.1 CDS ESA_02028 NC_009778.1 1963699 1963827 D Psort location: nuclear, score: 23; hypothetical protein 1963699..1963827 Cronobacter sakazakii ATCC BAA-894 5549862 YP_001438118.1 CDS ESA_02031 NC_009778.1 1964203 1964427 D Psort location: cytoplasmic, score: 23; hypothetical protein 1964203..1964427 Cronobacter sakazakii ATCC BAA-894 5549865 YP_001438119.1 CDS ESA_02032 NC_009778.1 1964491 1965042 R COG: NOG22997 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1964491..1965042) Cronobacter sakazakii ATCC BAA-894 5552128 YP_001438120.1 CDS ESA_02033 NC_009778.1 1965924 1966403 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1965924..1966403) Cronobacter sakazakii ATCC BAA-894 5549310 YP_001438121.1 CDS ESA_02034 NC_009778.1 1967100 1968098 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1967100..1968098) Cronobacter sakazakii ATCC BAA-894 5549246 YP_001438122.1 CDS ESA_02035 NC_009778.1 1968103 1969002 R COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1968103..1969002) Cronobacter sakazakii ATCC BAA-894 5549358 YP_001438123.1 CDS ESA_02036 NC_009778.1 1969450 1969905 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1969450..1969905) Cronobacter sakazakii ATCC BAA-894 5549417 YP_001438124.1 CDS ESA_02037 NC_009778.1 1970175 1972733 R COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1970175..1972733) Cronobacter sakazakii ATCC BAA-894 5552323 YP_001438125.1 CDS ESA_02038 NC_009778.1 1972737 1973258 R COG: COG3521 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 23; hypothetical protein complement(1972737..1973258) Cronobacter sakazakii ATCC BAA-894 5549352 YP_001438126.1 CDS ESA_02039 NC_009778.1 1973284 1974366 R COG: COG3520 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1973284..1974366) Cronobacter sakazakii ATCC BAA-894 5552146 YP_001438127.1 CDS ESA_02040 NC_009778.1 1974330 1976099 R COG: COG3519 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1974330..1976099) Cronobacter sakazakii ATCC BAA-894 5552486 YP_001438128.1 CDS ESA_02041 NC_009778.1 1976281 1977651 R COG: COG3523 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1976281..1977651) Cronobacter sakazakii ATCC BAA-894 5549264 YP_001438129.1 CDS ESA_02042 NC_009778.1 1977629 1978411 R KEGG: bpm:BURPS1710b_A0534 5.7e-48 hypothetical protein K00356; COG: COG3517 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1977629..1978411) Cronobacter sakazakii ATCC BAA-894 5549375 YP_001438130.1 CDS ESA_02043 NC_009778.1 1978446 1978958 R COG: COG3516 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(1978446..1978958) Cronobacter sakazakii ATCC BAA-894 5549388 YP_001438131.1 CDS ESA_02044 NC_009778.1 1979485 1979826 R Psort location: mitochondrial, score: 23; hypothetical protein complement(1979485..1979826) Cronobacter sakazakii ATCC BAA-894 5549270 YP_001438132.1 CDS ESA_02045 NC_009778.1 1979867 1980427 D COG: COG3911 Predicted ATPase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 1979867..1980427 Cronobacter sakazakii ATCC BAA-894 5549406 YP_001438133.1 CDS ESA_02046 NC_009778.1 1980521 1982551 R proton-motive-force-driven choline transporter; choline transport protein BetT complement(1980521..1982551) Cronobacter sakazakii ATCC BAA-894 5549314 YP_001438134.1 CDS ESA_02047 NC_009778.1 1982803 1983411 D HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 1982803..1983411 Cronobacter sakazakii ATCC BAA-894 5549410 YP_001438135.1 CDS ESA_02048 NC_009778.1 1983408 1984883 D catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 1983408..1984883 Cronobacter sakazakii ATCC BAA-894 5549348 YP_001438136.1 CDS ESA_02049 NC_009778.1 1984911 1986590 D catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 1984911..1986590 Cronobacter sakazakii ATCC BAA-894 5549303 YP_001438137.1 CDS ESA_02050 NC_009778.1 1986760 1987170 R COG: COG3791 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1986760..1987170) Cronobacter sakazakii ATCC BAA-894 5549263 YP_001438138.1 CDS ESA_02051 NC_009778.1 1987484 1987828 D Psort location: cytoplasmic, score: 23; hypothetical protein 1987484..1987828 Cronobacter sakazakii ATCC BAA-894 5549359 YP_001438139.1 CDS ESA_02052 NC_009778.1 1987874 1988092 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(1987874..1988092) Cronobacter sakazakii ATCC BAA-894 5549383 YP_001438140.1 CDS ESA_02053 NC_009778.1 1988207 1989589 R KEGG: sgl:SG1466 2.1e-08 dethiobiotinsynthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(1988207..1989589) Cronobacter sakazakii ATCC BAA-894 5549277 YP_001438141.1 CDS ESA_02054 NC_009778.1 1989715 1990626 D COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 1989715..1990626 Cronobacter sakazakii ATCC BAA-894 5549321 YP_001438142.1 CDS ESA_02056 NC_009778.1 1992973 1993995 R COG: COG3376 High-affinity nickel permease; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(1992973..1993995) Cronobacter sakazakii ATCC BAA-894 5549285 YP_001438143.1 CDS ESA_02057 NC_009778.1 1993989 1996235 R KEGG: pfu:PF0283 2.0e-05 putative acylphosphatase K01512; COG: COG0068 Hydrogenase maturation factor; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1993989..1996235) Cronobacter sakazakii ATCC BAA-894 5549444 YP_001438144.1 CDS ESA_02058 NC_009778.1 1996280 1998430 R KEGG: eca:ECA1250 0. fdhF; formate dehydrogenase H K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: cytoplasmic, score: 23; hypothetical protein complement(1996280..1998430) Cronobacter sakazakii ATCC BAA-894 5549712 YP_001438145.1 CDS ESA_02059 NC_009778.1 1998465 1999013 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(1998465..1999013) Cronobacter sakazakii ATCC BAA-894 5549332 YP_001438146.1 CDS ESA_02060 NC_009778.1 1999213 1999476 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(1999213..1999476) Cronobacter sakazakii ATCC BAA-894 5550197 YP_001438147.1 CDS hycI NC_009778.1 1999981 2000421 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(1999981..2000421) Cronobacter sakazakii ATCC BAA-894 5549696 YP_001438148.1 CDS ESA_02062 NC_009778.1 2000447 2000854 R KEGG: eci:UTI89_C3081 2.3e-45 hycH; formate hydrogenlyase maturation protein HycH; COG: NOG09848 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2000447..2000854) Cronobacter sakazakii ATCC BAA-894 5549715 YP_001438149.1 CDS ESA_02063 NC_009778.1 2000851 2001615 R KEGG: eci:UTI89_C3082 1.8e-116 hycG; formate hydrogenlyase subunit 7; COG: COG3260 Ni,Fe-hydrogenase III small subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2000851..2001615) Cronobacter sakazakii ATCC BAA-894 5549746 YP_001438150.1 CDS ESA_02064 NC_009778.1 2001615 2002157 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(2001615..2002157) Cronobacter sakazakii ATCC BAA-894 5552075 YP_001438151.1 CDS ESA_02065 NC_009778.1 2002331 2004040 R KEGG: eci:UTI89_C3084 4.1e-300 hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2002331..2004040) Cronobacter sakazakii ATCC BAA-894 5549925 YP_001438152.1 CDS ESA_02066 NC_009778.1 2004056 2004982 R KEGG: eci:UTI89_C3085 8.1e-130 hycD; membrane-spanning protein of formate hydrogenase; COG: COG0650 Formate hydrogenlyase subunit 4; Psort location: plasma membrane, score: 23; hypothetical protein complement(2004056..2004982) Cronobacter sakazakii ATCC BAA-894 5549933 YP_001438153.1 CDS ESA_02067 NC_009778.1 2004984 2006810 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(2004984..2006810) Cronobacter sakazakii ATCC BAA-894 5550093 YP_001438154.1 CDS ESA_02068 NC_009778.1 2006810 2007298 R KEGG: eci:UTI89_C3087 6.0e-70 hycB; formate hydrogenlyase subunit 2; COG: COG1142 Fe-S-cluster-containing hydrogenase components 2; Psort location: nuclear, score: 23; hypothetical protein complement(2006810..2007298) Cronobacter sakazakii ATCC BAA-894 5549990 YP_001438155.1 CDS ESA_02069 NC_009778.1 2007498 2007962 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(2007498..2007962) Cronobacter sakazakii ATCC BAA-894 5550010 YP_001438156.1 CDS ESA_02070 NC_009778.1 2008073 2008546 D COG: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Psort location: cytoplasmic, score: 23; hypothetical protein 2008073..2008546 Cronobacter sakazakii ATCC BAA-894 5550077 YP_001438157.1 CDS ESA_02071 NC_009778.1 2008550 2009422 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 2008550..2009422 Cronobacter sakazakii ATCC BAA-894 5550080 YP_001438158.1 CDS ESA_02072 NC_009778.1 2009413 2009691 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 2009413..2009691 Cronobacter sakazakii ATCC BAA-894 5552457 YP_001438159.1 CDS ESA_02073 NC_009778.1 2009691 2010812 D COG: COG0409 Hydrogenase maturation factor; Psort location: cytoplasmic, score: 23; hypothetical protein 2009691..2010812 Cronobacter sakazakii ATCC BAA-894 5550029 YP_001438160.1 CDS ESA_02074 NC_009778.1 2010809 2011819 D KEGG: cch:Cag_0556 3.2e-80 hypE; hydrogenase expression/formation protein HypE K04655; COG: COG0309 Hydrogenase maturation factor; Psort location: cytoplasmic, score: 23; hypothetical protein 2010809..2011819 Cronobacter sakazakii ATCC BAA-894 5550044 YP_001438161.1 CDS ESA_02075 NC_009778.1 2011927 2013987 D KEGG: eci:UTI89_C3094 2.9e-283 fhlA; formate hydrogenlyase transcriptional activator K01768; COG: COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; Psort location: cytoplasmic, score: 23; hypothetical protein 2011927..2013987 Cronobacter sakazakii ATCC BAA-894 5552452 YP_001438162.1 CDS ESA_02076 NC_009778.1 2014426 2015787 R KEGG: eci:UTI89_C0120 7.0e-12 aroP; aromatic amino acid transport protein AroP K03293; COG: COG0531 Amino acid transporters; Psort location: plasma membrane, score: 23; hypothetical protein complement(2014426..2015787) Cronobacter sakazakii ATCC BAA-894 5550131 YP_001438163.1 CDS ESA_02077 NC_009778.1 2015777 2016151 R Psort location: nuclear, score: 23; hypothetical protein complement(2015777..2016151) Cronobacter sakazakii ATCC BAA-894 5549787 YP_001438164.1 CDS ESA_02078 NC_009778.1 2016180 2017598 R KEGG: ecs:ECs1874 7.3e-216 putative glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2016180..2017598) Cronobacter sakazakii ATCC BAA-894 5552111 YP_001438165.1 CDS puuD NC_009778.1 2017810 2018577 D catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 2017810..2018577 Cronobacter sakazakii ATCC BAA-894 5552434 YP_001438166.1 CDS ESA_02080 NC_009778.1 2018602 2019159 D regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 2018602..2019159 Cronobacter sakazakii ATCC BAA-894 5552415 YP_001438167.1 CDS ESA_02081 NC_009778.1 2019090 2019266 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2019090..2019266) Cronobacter sakazakii ATCC BAA-894 5552195 YP_001438168.1 CDS ESA_02082 NC_009778.1 2019326 2020825 D catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 2019326..2020825 Cronobacter sakazakii ATCC BAA-894 5549908 YP_001438169.1 CDS ESA_02083 NC_009778.1 2020818 2022098 D KEGG: ecj:JW1294 1.2e-190 puuB; gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: cytoplasmic, score: 23; hypothetical protein 2020818..2022098 Cronobacter sakazakii ATCC BAA-894 5549616 YP_001438170.1 CDS ESA_02084 NC_009778.1 2022681 2029751 R KEGG: eci:UTI89_C1139 6.9e-134 putative autotransporter; COG: COG3468 Type V secretory pathway, adhesin AidA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2022681..2029751) Cronobacter sakazakii ATCC BAA-894 5549726 YP_001438171.1 CDS ESA_02085 NC_009778.1 2029783 2031045 R KEGG: gbe:GbCGDNIH1_1646 5.1e-105 glycosyltransferase K00754; COG: NOG08921 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2029783..2031045) Cronobacter sakazakii ATCC BAA-894 5549706 YP_001438172.1 CDS ESA_02086 NC_009778.1 2031956 2033464 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2031956..2033464 Cronobacter sakazakii ATCC BAA-894 5549733 YP_001438173.1 CDS ESA_02087 NC_009778.1 2033778 2034014 D COG: COG4238 Murein lipoprotein; Psort location: nuclear, score: 23; hypothetical protein 2033778..2034014 Cronobacter sakazakii ATCC BAA-894 5550305 YP_001438174.1 CDS ESA_02088 NC_009778.1 2034166 2035200 R KEGG: eci:UTI89_C2228 1.1e-72 erfK; hypothetical protein K00257; COG: COG1376 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2034166..2035200) Cronobacter sakazakii ATCC BAA-894 5549831 YP_001438175.1 CDS ESA_02089 NC_009778.1 2035294 2035710 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(2035294..2035710) Cronobacter sakazakii ATCC BAA-894 5550273 YP_001438176.1 CDS ESA_02090 NC_009778.1 2035722 2036942 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(2035722..2036942) Cronobacter sakazakii ATCC BAA-894 5549717 YP_001438177.1 CDS ESA_02091 NC_009778.1 2036939 2038213 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(2036939..2038213) Cronobacter sakazakii ATCC BAA-894 5549841 YP_001438178.1 CDS sufC NC_009778.1 2038188 2038934 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase component complement(2038188..2038934) Cronobacter sakazakii ATCC BAA-894 5549792 YP_001438179.1 CDS ESA_02093 NC_009778.1 2038955 2040445 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(2038955..2040445) Cronobacter sakazakii ATCC BAA-894 5549426 YP_001438180.1 CDS sufA NC_009778.1 2040448 2040825 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(2040448..2040825) Cronobacter sakazakii ATCC BAA-894 5549843 YP_001438181.1 CDS ESA_02095 NC_009778.1 2041349 2042665 R KEGG: ecp:ECP_0985 1.4e-132 periplasmic AppA protein precursor K01078:K01093; COG: NOG06767 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; phosphoanhydride phosphorylase complement(2041349..2042665) Cronobacter sakazakii ATCC BAA-894 5551993 YP_001438182.1 CDS ESA_02096 NC_009778.1 2043105 2043515 R KEGG: eco:b1686 6.0e-54 ydiI; hypothetical protein; COG: COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; Psort location: cytoskeletal, score: 9; hypothetical protein complement(2043105..2043515) Cronobacter sakazakii ATCC BAA-894 5549745 YP_001438183.1 CDS ESA_02097 NC_009778.1 2043512 2046568 R KEGG: eci:UTI89_C1879 0. ydiJ; hypothetical protein YdiJ; COG: COG0247 Fe-S oxidoreductase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2043512..2046568) Cronobacter sakazakii ATCC BAA-894 5549637 YP_001438184.1 CDS ESA_02098 NC_009778.1 2046774 2047901 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 2046774..2047901 Cronobacter sakazakii ATCC BAA-894 5549479 YP_001438185.1 CDS ESA_02100 NC_009778.1 2048208 2050577 R KEGG: ppr:PBPRA0461 9.2e-248 putative xylosidase K05349; COG: COG1472 Beta-glucosidase-related glycosidases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2048208..2050577) Cronobacter sakazakii ATCC BAA-894 5549460 YP_001438186.1 CDS ESA_02101 NC_009778.1 2050581 2051969 R uncharacterized member of the GPH family of galactose-pentose-hexuronide transporters; putative symporter YagG complement(2050581..2051969) Cronobacter sakazakii ATCC BAA-894 5550212 YP_001438187.1 CDS ESA_02102 NC_009778.1 2052188 2054566 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(2052188..2054566) Cronobacter sakazakii ATCC BAA-894 5550290 YP_001438188.1 CDS ESA_02103 NC_009778.1 2054899 2055732 D COG: COG1806 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 2054899..2055732 Cronobacter sakazakii ATCC BAA-894 5552483 YP_001438189.1 CDS ESA_02104 NC_009778.1 2055833 2056933 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2055833..2056933 Cronobacter sakazakii ATCC BAA-894 5549752 YP_001438190.1 CDS ESA_02105 NC_009778.1 2057009 2058457 R COG: COG0397 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2057009..2058457) Cronobacter sakazakii ATCC BAA-894 5549219 YP_001438191.1 CDS ESA_02106 NC_009778.1 2058519 2059238 R COG: COG2200 FOG: EAL domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2058519..2059238) Cronobacter sakazakii ATCC BAA-894 5549986 YP_001438192.1 CDS ESA_02107 NC_009778.1 2059390 2060379 R KEGG: msm:MSMEG_3095 4.2e-05 D-ribose-binding periplasmic protein; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2059390..2060379) Cronobacter sakazakii ATCC BAA-894 5550113 YP_001438193.1 CDS ESA_02108 NC_009778.1 2060443 2061759 R KEGG: plu:plu2757 5.7e-177 celF; 6-phospho-beta-glucosidase (cellobiose-6-phosphate hydrolase) K01222; COG: COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2060443..2061759) Cronobacter sakazakii ATCC BAA-894 5550270 YP_001438194.1 CDS ESA_02109 NC_009778.1 2061756 2063093 R KEGG: eca:ECA2488 2.4e-114 PTS system, cellobiose-specific IIc component K02761; COG: COG1455 Phosphotransferase system cellobiose-specific component IIC; Psort location: plasma membrane, score: 23; hypothetical protein complement(2061756..2063093) Cronobacter sakazakii ATCC BAA-894 5549813 YP_001438195.1 CDS ESA_02110 NC_009778.1 2063286 2063750 R KEGG: eci:UTI89_C1901 1.3e-67 nlpC; probable lipoprotein NlpC precursor; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2063286..2063750) Cronobacter sakazakii ATCC BAA-894 5550019 YP_001438196.1 CDS ESA_02111 NC_009778.1 2063828 2064571 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(2063828..2064571) Cronobacter sakazakii ATCC BAA-894 5549781 YP_001438197.1 CDS btuE NC_009778.1 2064574 2065125 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase complement(2064574..2065125) Cronobacter sakazakii ATCC BAA-894 5550052 YP_001438198.1 CDS ESA_02113 NC_009778.1 2065155 2066156 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(2065155..2066156) Cronobacter sakazakii ATCC BAA-894 5549756 YP_001438199.1 CDS ihfA NC_009778.1 2066234 2066533 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(2066234..2066533) Cronobacter sakazakii ATCC BAA-894 5550037 YP_001438200.1 CDS pheT NC_009778.1 2066538 2068925 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2066538..2068925) Cronobacter sakazakii ATCC BAA-894 5549499 YP_001438201.1 CDS pheS NC_009778.1 2068941 2069924 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(2068941..2069924) Cronobacter sakazakii ATCC BAA-894 5549820 YP_001438202.1 CDS ESA_02117 NC_009778.1 2070102 2070230 D Psort location: cytoplasmic, score: 23; hypothetical protein 2070102..2070230 Cronobacter sakazakii ATCC BAA-894 5550100 YP_001438203.1 CDS rplT NC_009778.1 2070310 2070666 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(2070310..2070666) Cronobacter sakazakii ATCC BAA-894 5549928 YP_001438204.1 CDS rpmI NC_009778.1 2070714 2070911 R COG: COG0291 Ribosomal protein L35; Psort location: cytoplasmic, score: 23; 50S ribosomal protein L35 complement(2070714..2070911) Cronobacter sakazakii ATCC BAA-894 5552405 YP_001438205.1 CDS ESA_02119 NC_009778.1 2070783 2070971 D Psort location: cytoplasmic, score: 23; hypothetical protein 2070783..2070971 Cronobacter sakazakii ATCC BAA-894 5549514 YP_001438206.1 CDS ESA_02121 NC_009778.1 2071000 2071395 D Psort location: cytoplasmic, score: 23; hypothetical protein 2071000..2071395 Cronobacter sakazakii ATCC BAA-894 5549602 YP_001438207.1 CDS infC NC_009778.1 2071009 2071443 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(2071009..2071443) Cronobacter sakazakii ATCC BAA-894 5549653 YP_001438208.1 CDS ESA_02124 NC_009778.1 2071555 2072916 R KEGG: stt:t1213 1.7e-246 thrS; threonyl-tRNA synthetase K01868; COG: COG0441 Threonyl-tRNA synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2071555..2072916) Cronobacter sakazakii ATCC BAA-894 5549600 YP_001438209.1 CDS ESA_02123 NC_009778.1 2072902 2073531 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2072902..2073531 Cronobacter sakazakii ATCC BAA-894 5549719 YP_001438210.1 CDS ESA_02125 NC_009778.1 2073812 2074288 R KEGG: bur:Bcep18194_A5735 3.2e-48 GCN5-related N-acetyltransferase K00657; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2073812..2074288) Cronobacter sakazakii ATCC BAA-894 5549594 YP_001438211.1 CDS ESA_02126 NC_009778.1 2074380 2075300 D COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 2074380..2075300 Cronobacter sakazakii ATCC BAA-894 5549846 YP_001438212.1 CDS ESA_02127 NC_009778.1 2075521 2076441 D KEGG: ecp:ECP_4098 1.8e-109 acetyl-hydrolase K01066; COG: COG0657 Esterase/lipase; Psort location: cytoplasmic, score: 23; hypothetical protein 2075521..2076441 Cronobacter sakazakii ATCC BAA-894 5549786 YP_001438213.1 CDS ESA_02128 NC_009778.1 2076452 2076898 R KEGG: tte:TTE0537 6.8e-07 rimI3; Acetyltransferases K03789; COG: NOG16293 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2076452..2076898) Cronobacter sakazakii ATCC BAA-894 5550257 YP_001438214.1 CDS ESA_02129 NC_009778.1 2077070 2077579 R COG: COG4574 Serine protease inhibitor ecotin; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2077070..2077579) Cronobacter sakazakii ATCC BAA-894 5549647 YP_001438215.1 CDS ESA_02130 NC_009778.1 2077786 2078235 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2077786..2078235) Cronobacter sakazakii ATCC BAA-894 5549578 YP_001438216.1 CDS ESA_02131 NC_009778.1 2078412 2079929 R KEGG: cal:orf19.2425 5.1e-05 highly conserved hypothetical protein K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; proline/glycine betaine transporter complement(2078412..2079929) Cronobacter sakazakii ATCC BAA-894 5549573 YP_001438217.1 CDS ESA_02132 NC_009778.1 2080432 2080659 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2080432..2080659) Cronobacter sakazakii ATCC BAA-894 5549423 YP_001438218.1 CDS ESA_02133 NC_009778.1 2080931 2081707 R COG: COG3137 Putative salt-induced outer membrane protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2080931..2081707) Cronobacter sakazakii ATCC BAA-894 5549690 YP_001438219.1 CDS ESA_02134 NC_009778.1 2081983 2082912 D KEGG: stm:STM1326 4.7e-134 pfkB; 6-phosphofructokinase II K00850; COG: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Psort location: extracellular, including cell wall, score: 9; 6-phosphofructokinase 2 2081983..2082912 Cronobacter sakazakii ATCC BAA-894 5549436 YP_001438220.1 CDS ESA_02135 NC_009778.1 2082955 2083257 D COG: NOG12163 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2082955..2083257 Cronobacter sakazakii ATCC BAA-894 5551870 YP_001438221.1 CDS ESA_02136 NC_009778.1 2083355 2084215 D KEGG: eci:UTI89_C1919 2.2e-127 yniA; hypothetical protein YniA K00924; COG: COG3001 Fructosamine-3-kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 2083355..2084215 Cronobacter sakazakii ATCC BAA-894 5549507 YP_001438222.1 CDS ESA_02137 NC_009778.1 2084240 2084776 R COG: NOG07880 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(2084240..2084776) Cronobacter sakazakii ATCC BAA-894 5549456 YP_001438223.1 CDS ESA_02138 NC_009778.1 2084935 2085603 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2084935..2085603 Cronobacter sakazakii ATCC BAA-894 5549450 YP_001438224.1 CDS ESA_02139 NC_009778.1 2085791 2086546 D KEGG: vvy:VVA1401 1.9e-96 dehydrogenase K00065; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 2085791..2086546 Cronobacter sakazakii ATCC BAA-894 5549471 YP_001438225.1 CDS ESA_02140 NC_009778.1 2086660 2087250 D COG: COG1988 Predicted membrane-bound metal-dependent hydrolases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2086660..2087250 Cronobacter sakazakii ATCC BAA-894 5549529 YP_001438226.1 CDS ESA_02141 NC_009778.1 2087385 2088776 D KEGG: eci:UTI89_C4668 3.0e-36 gltP; glutamate-aspartate symport protein K03309; COG: COG1823 Predicted Na+/dicarboxylate symporter; Psort location: plasma membrane, score: 23; hypothetical protein 2087385..2088776 Cronobacter sakazakii ATCC BAA-894 5549530 YP_001438227.1 CDS ESA_02142 NC_009778.1 2088888 2089235 R COG: COG3093 Plasmid maintenance system antidote protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2088888..2089235) Cronobacter sakazakii ATCC BAA-894 5549536 YP_001438228.1 CDS ESA_02143 NC_009778.1 2089262 2089441 R COG: COG3549 Plasmid maintenance system killer protein; Psort location: mitochondrial, score: 23; hypothetical protein complement(2089262..2089441) Cronobacter sakazakii ATCC BAA-894 5549655 YP_001438229.1 CDS ESA_02144 NC_009778.1 2089383 2089565 R COG: COG3549 Plasmid maintenance system killer protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2089383..2089565) Cronobacter sakazakii ATCC BAA-894 5549707 YP_001438230.1 CDS ESA_02145 NC_009778.1 2089729 2089875 R COG: NOG11329 non supervised orthologous group; Psort location: cytoplasmic, score: 23; cell division modulator complement(2089729..2089875) Cronobacter sakazakii ATCC BAA-894 5549635 YP_001438231.1 CDS katE NC_009778.1 2090171 2092426 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2090171..2092426 Cronobacter sakazakii ATCC BAA-894 5549852 YP_001438232.1 CDS ESA_02147 NC_009778.1 2092539 2092880 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(2092539..2092880) Cronobacter sakazakii ATCC BAA-894 5550046 YP_001438233.1 CDS nadE NC_009778.1 2093123 2093950 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2093123..2093950 Cronobacter sakazakii ATCC BAA-894 5550101 YP_001438234.1 CDS ESA_02149 NC_009778.1 2094037 2094927 D KEGG: pae:PA1977 0.0011 sensor protein GLPS; COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 2094037..2094927 Cronobacter sakazakii ATCC BAA-894 5550018 YP_001438235.1 CDS ESA_02150 NC_009778.1 2094995 2095876 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2094995..2095876 Cronobacter sakazakii ATCC BAA-894 5549747 YP_001438236.1 CDS ESA_02151 NC_009778.1 2095867 2096436 R COG: COG3758 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2095867..2096436) Cronobacter sakazakii ATCC BAA-894 5550060 YP_001438237.1 CDS ESA_02152 NC_009778.1 2096689 2097171 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein complement(2096689..2097171) Cronobacter sakazakii ATCC BAA-894 5549989 YP_001438238.1 CDS ESA_02153 NC_009778.1 2097466 2098431 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(2097466..2098431) Cronobacter sakazakii ATCC BAA-894 5552108 YP_001438239.1 CDS ESA_02154 NC_009778.1 2098441 2099766 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(2098441..2099766) Cronobacter sakazakii ATCC BAA-894 5549903 YP_001438240.1 CDS ESA_02155 NC_009778.1 2099763 2101241 R KEGG: eco:b1746 1.4e-210 astD, ydjU; succinylglutamic semialdehyde dehydrogenase K06447; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2099763..2101241) Cronobacter sakazakii ATCC BAA-894 5550034 YP_001438241.1 CDS ESA_02156 NC_009778.1 2101238 2102275 R KEGG: ecj:JW1736 4.4e-154 astA; arginine succinyltransferase K00673; COG: COG3138 Arginine/orniTHIne N-succinyltransferase beta subunit; Psort location: cytoplasmic, score: 23; arginine succinyltransferase complement(2101238..2102275) Cronobacter sakazakii ATCC BAA-894 5549987 YP_001438242.1 CDS ESA_02157 NC_009778.1 2102272 2103492 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(2102272..2103492) Cronobacter sakazakii ATCC BAA-894 5550002 YP_001438243.1 CDS ESA_02158 NC_009778.1 2103934 2104740 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2103934..2104740 Cronobacter sakazakii ATCC BAA-894 5549965 YP_001438244.1 CDS ESA_02159 NC_009778.1 2104789 2105202 D KEGG: eco:b1759 5.5e-44 nudG, ynjG, orf135; CTP pyrophosphohydrolase K08320; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2104789..2105202 Cronobacter sakazakii ATCC BAA-894 5550174 YP_001438245.1 CDS ESA_02160 NC_009778.1 2105162 2105479 R COG: NOG11328 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(2105162..2105479) Cronobacter sakazakii ATCC BAA-894 5550238 YP_001438246.1 CDS ESA_02161 NC_009778.1 2105545 2107491 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(2105545..2107491) Cronobacter sakazakii ATCC BAA-894 5550193 YP_001438247.1 CDS ESA_02162 NC_009778.1 2107495 2108538 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(2107495..2108538) Cronobacter sakazakii ATCC BAA-894 5550213 YP_001438248.1 CDS ESA_02163 NC_009778.1 2108531 2108659 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2108531..2108659) Cronobacter sakazakii ATCC BAA-894 5550179 YP_001438249.1 CDS ESA_02164 NC_009778.1 2108686 2109267 R KEGG: sbo:SBO_1322 1.1e-77 ydjA; hypothetical protein; COG: COG0778 Nitroreductase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2108686..2109267) Cronobacter sakazakii ATCC BAA-894 5550206 YP_001438250.1 CDS ESA_02165 NC_009778.1 2109412 2111262 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2109412..2111262 Cronobacter sakazakii ATCC BAA-894 5549449 YP_001438251.1 CDS ansA NC_009778.1 2111363 2112379 D converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2111363..2112379 Cronobacter sakazakii ATCC BAA-894 5549488 YP_001438252.1 CDS ESA_02167 NC_009778.1 2112392 2113033 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2112392..2113033 Cronobacter sakazakii ATCC BAA-894 5549681 YP_001438253.1 CDS ESA_02168 NC_009778.1 2113114 2113464 R COG: COG3139 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(2113114..2113464) Cronobacter sakazakii ATCC BAA-894 5549520 YP_001438254.1 CDS ESA_02169 NC_009778.1 2113433 2113846 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(2113433..2113846) Cronobacter sakazakii ATCC BAA-894 5549481 YP_001438255.1 CDS ESA_02170 NC_009778.1 2114192 2115187 D KEGG: ecs:ECs2488 5.4e-172 glyceraldehyde-3-phosphate dehydrogenase A K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: cytoplasmic, score: 23; hypothetical protein 2114192..2115187 Cronobacter sakazakii ATCC BAA-894 5549605 YP_001438256.1 CDS ESA_02171 NC_009778.1 2115264 2116151 D KEGG: azo:azo1660 1.3e-35 conserved hypothetical protein K01785; COG: COG0676 Uncharacterized enzymes related to aldose 1-epimerase; Psort location: cytoplasmic, score: 23; hypothetical protein 2115264..2116151 Cronobacter sakazakii ATCC BAA-894 5550196 YP_001438257.1 CDS ESA_02172 NC_009778.1 2116265 2116975 R COG: COG3713 Outer membrane protein V; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2116265..2116975) Cronobacter sakazakii ATCC BAA-894 5549607 YP_001438258.1 CDS ESA_02173 NC_009778.1 2117446 2119380 D KEGG: eci:UTI89_C1979 0. yeaG; hypothetical protein K07180; COG: COG2766 Putative Ser protein kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 2117446..2119380 Cronobacter sakazakii ATCC BAA-894 5549574 YP_001438259.1 CDS ESA_02174 NC_009778.1 2119485 2120786 D KEGG: eci:UTI89_C1980 7.0e-211 yeaH; hypothetical protein YeaH K00754; COG: COG2718 Uncharacterized conserved protein; Psort location: nuclear, score: 23; hypothetical protein 2119485..2120786 Cronobacter sakazakii ATCC BAA-894 5550293 YP_001438260.1 CDS ESA_02175 NC_009778.1 2121030 2122592 D KEGG: vfi:VF0494 2.9e-26 sensory transduction protein kinase; COG: COG4943 Predicted signal transduction protein containing sensor and EAL domains; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2121030..2122592 Cronobacter sakazakii ATCC BAA-894 5549693 YP_001438263.1 CDS ESA_02178 NC_009778.1 2122643 2122876 R COG: COG3729 General stress protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2122643..2122876) Cronobacter sakazakii ATCC BAA-894 5549627 YP_001438264.1 CDS ESA_02179 NC_009778.1 2123253 2123777 D COG: COG2606 Uncharacterized conserved protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2123253..2123777 Cronobacter sakazakii ATCC BAA-894 5550201 YP_001438265.1 CDS ESA_02180 NC_009778.1 2123965 2124411 D COG: COG2707 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein 2123965..2124411 Cronobacter sakazakii ATCC BAA-894 5549737 YP_001438266.1 CDS ESA_02181 NC_009778.1 2124484 2125668 D KEGG: gme:Gmet_0086 1.9e-05 2-acyl-glycerophospho-ethanolamine acyltransferase K05939:K01909; COG: COG2807 Cyanate permease; Psort location: plasma membrane, score: 23; hypothetical protein 2124484..2125668 Cronobacter sakazakii ATCC BAA-894 5551971 YP_001438267.1 CDS ESA_02182 NC_009778.1 2125670 2126482 R KEGG: aba:Acid345_2856 7.2e-58 CTP synthase K01937; COG: COG0504 CTP synthase (UTP-ammonia lyase); Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2125670..2126482) Cronobacter sakazakii ATCC BAA-894 5550246 YP_001438268.1 CDS ESA_02183 NC_009778.1 2126581 2126937 D KEGG: eci:UTI89_C1988 1.3e-35 yeaO; hypothetical protein K00589; COG: COG3189 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 2126581..2126937 Cronobacter sakazakii ATCC BAA-894 5549830 YP_001438269.1 CDS ESA_02184 NC_009778.1 2126907 2127272 D Psort location: cytoplasmic, score: 23; hypothetical protein 2126907..2127272 Cronobacter sakazakii ATCC BAA-894 5549730 YP_001438270.1 CDS ESA_02185 NC_009778.1 2126934 2127239 R COG: NOG29442 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2126934..2127239) Cronobacter sakazakii ATCC BAA-894 5552265 YP_001438271.1 CDS ESA_02186 NC_009778.1 2127283 2127516 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2127283..2127516) Cronobacter sakazakii ATCC BAA-894 5549829 YP_001438272.1 CDS ESA_02187 NC_009778.1 2127676 2128617 D COG: COG2990 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 2127676..2128617 Cronobacter sakazakii ATCC BAA-894 5549832 YP_001438273.1 CDS ESA_02188 NC_009778.1 2128738 2129934 D Psort location: cytoplasmic, score: 23; hypothetical protein 2128738..2129934 Cronobacter sakazakii ATCC BAA-894 5550165 YP_001438274.1 CDS ESA_02189 NC_009778.1 2129975 2130148 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2129975..2130148) Cronobacter sakazakii ATCC BAA-894 5550220 YP_001438275.1 CDS ESA_02190 NC_009778.1 2130273 2131241 R KEGG: stm:STM2314 2.4e-121 putative chemotaxis signal transduction protein K03415; COG: COG0784 FOG: CheY-like receiver; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2130273..2131241) Cronobacter sakazakii ATCC BAA-894 5550223 YP_001438276.1 CDS ESA_02191 NC_009778.1 2131275 2131427 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2131275..2131427) Cronobacter sakazakii ATCC BAA-894 5550292 YP_001438277.1 CDS ESA_02192 NC_009778.1 2131468 2131638 R Psort location: nuclear, score: 23; hypothetical protein complement(2131468..2131638) Cronobacter sakazakii ATCC BAA-894 5552164 YP_001438278.1 CDS ESA_02193 NC_009778.1 2131786 2132022 D Psort location: cytoplasmic, score: 23; hypothetical protein 2131786..2132022 Cronobacter sakazakii ATCC BAA-894 5550288 YP_001438279.1 CDS ESA_02194 NC_009778.1 2132139 2132363 R COG: COG1278 Cold shock proteins; Psort location: nuclear, score: 23; hypothetical protein complement(2132139..2132363) Cronobacter sakazakii ATCC BAA-894 5552140 YP_001438280.1 CDS ESA_02195 NC_009778.1 2132347 2132559 R COG: COG1278 Cold shock proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2132347..2132559) Cronobacter sakazakii ATCC BAA-894 5552112 YP_001438281.1 CDS ESA_02196 NC_009778.1 2133069 2133746 D COG: COG1636 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 2133069..2133746 Cronobacter sakazakii ATCC BAA-894 5552100 YP_001438282.1 CDS ESA_02197 NC_009778.1 2133812 2134192 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2133812..2134192) Cronobacter sakazakii ATCC BAA-894 5552114 YP_001438283.1 CDS ESA_02198 NC_009778.1 2134987 2136552 D KEGG: bxe:Bxe_B3011 1.7e-06 CheA signal transduction histidine kinases (STHK); COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2134987..2136552 Cronobacter sakazakii ATCC BAA-894 5552127 YP_001438284.1 CDS ESA_02199 NC_009778.1 2136757 2137560 D Psort location: cytoplasmic, score: 23; hypothetical protein 2136757..2137560 Cronobacter sakazakii ATCC BAA-894 5552121 YP_001438285.1 CDS ESA_02200 NC_009778.1 2137631 2137816 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2137631..2137816) Cronobacter sakazakii ATCC BAA-894 5552094 YP_001438286.1 CDS ESA_02201 NC_009778.1 2137914 2138480 D Psort location: cytoplasmic, score: 23; hypothetical protein 2137914..2138480 Cronobacter sakazakii ATCC BAA-894 5552078 YP_001438287.1 CDS ESA_02202 NC_009778.1 2138644 2139582 R KEGG: bxe:Bxe_A4064 3.4e-44 putative lipase/esterase; COG: COG0657 Esterase/lipase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2138644..2139582) Cronobacter sakazakii ATCC BAA-894 5552087 YP_001438288.1 CDS ESA_02203 NC_009778.1 2139653 2140588 D KEGG: shn:Shewana3_3435 0.0048 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 2139653..2140588 Cronobacter sakazakii ATCC BAA-894 5552074 YP_001438290.1 CDS ESA_02205 NC_009778.1 2140714 2141130 R KEGG: azo:azo3708 9.2e-19 dioxygenase-family protein K01759; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2140714..2141130) Cronobacter sakazakii ATCC BAA-894 5552065 YP_001438291.1 CDS ESA_02206 NC_009778.1 2141359 2141487 D Psort location: cytoplasmic, score: 23; hypothetical protein 2141359..2141487 Cronobacter sakazakii ATCC BAA-894 5552069 YP_001438292.1 CDS ESA_02207 NC_009778.1 2141469 2141816 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2141469..2141816) Cronobacter sakazakii ATCC BAA-894 5552024 YP_001438293.1 CDS ESA_02208 NC_009778.1 2141813 2142187 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2141813..2142187) Cronobacter sakazakii ATCC BAA-894 5552023 YP_001438294.1 CDS ESA_02209 NC_009778.1 2142555 2143805 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(2142555..2143805) Cronobacter sakazakii ATCC BAA-894 5551990 YP_001438295.1 CDS ESA_02210 NC_009778.1 2143921 2144577 D KEGG: eci:UTI89_C1264 1.7e-95 rluE; 23S rRNA pseudouridine synthase K06181; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: nuclear, score: 23; hypothetical protein 2143921..2144577 Cronobacter sakazakii ATCC BAA-894 5552035 YP_001438296.1 CDS ESA_02211 NC_009778.1 2144588 2145037 D KEGG: ece:Z1863 4.4e-67 putative phosphohydrolase; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 2144588..2145037 Cronobacter sakazakii ATCC BAA-894 5551968 YP_001438297.1 CDS ESA_02212 NC_009778.1 2145306 2147255 D KEGG: mma:MM2965 9.7e-27 hypothetical sensory transduction histidine kinase; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 2145306..2147255 Cronobacter sakazakii ATCC BAA-894 5551998 YP_001438298.1 CDS mnmA NC_009778.1 2147445 2148554 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2147445..2148554 Cronobacter sakazakii ATCC BAA-894 5551999 YP_001438299.1 CDS ESA_02214 NC_009778.1 2148609 2149238 D HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 2148609..2149238 Cronobacter sakazakii ATCC BAA-894 5551951 YP_001438300.1 CDS ESA_02215 NC_009778.1 2149256 2150626 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 2149256..2150626 Cronobacter sakazakii ATCC BAA-894 5551955 YP_001438301.1 CDS ESA_02216 NC_009778.1 2150781 2151452 D response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 2150781..2151452 Cronobacter sakazakii ATCC BAA-894 5551975 YP_001438302.1 CDS ESA_02217 NC_009778.1 2151453 2152958 D KEGG: sty:STY1270 1.9e-199 phoQ; sensor protein PhoQ, regulator of virulence determinants K07637; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; sensor protein PhoQ 2151453..2152958 Cronobacter sakazakii ATCC BAA-894 5552072 YP_001438303.1 CDS ESA_02218 NC_009778.1 2153008 2154129 D COG: COG2850 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 2153008..2154129 Cronobacter sakazakii ATCC BAA-894 5551979 YP_001438304.1 CDS ESA_02219 NC_009778.1 2154414 2155679 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(2154414..2155679) Cronobacter sakazakii ATCC BAA-894 5551985 YP_001438305.1 CDS ESA_02221 NC_009778.1 2155705 2155905 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2155705..2155905) Cronobacter sakazakii ATCC BAA-894 5551944 YP_001438306.1 CDS potA NC_009778.1 2155862 2157079 D functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein 2155862..2157079 Cronobacter sakazakii ATCC BAA-894 5551969 YP_001438307.1 CDS potB NC_009778.1 2157063 2157920 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 2157063..2157920 Cronobacter sakazakii ATCC BAA-894 5551965 YP_001438308.1 CDS potC NC_009778.1 2157917 2158729 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 2157917..2158729 Cronobacter sakazakii ATCC BAA-894 5551943 YP_001438309.1 CDS potD NC_009778.1 2158726 2159772 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter periplasmic substrate-binding protein 2158726..2159772 Cronobacter sakazakii ATCC BAA-894 5550219 YP_001438310.1 CDS ESA_02225 NC_009778.1 2159997 2160722 R KEGG: stm:STM1221 1.6e-115 cobB; putative nicotinate-nucleotide dimethylbenzimidazolephosphoribosltransferase, homolog of virulence factor K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2159997..2160722) Cronobacter sakazakii ATCC BAA-894 5551964 YP_001438311.1 CDS ESA_02226 NC_009778.1 2160823 2161743 R catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase complement(2160823..2161743) Cronobacter sakazakii ATCC BAA-894 5551907 YP_001438312.1 CDS ESA_02227 NC_009778.1 2161759 2162940 R part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE complement(2161759..2162940) Cronobacter sakazakii ATCC BAA-894 5551807 YP_001438313.1 CDS ESA_02228 NC_009778.1 2163003 2163707 R KEGG: pen:PSEEN3707 1.0e-67 lipoprotein releasing system, ATP-binding protein LolD; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2163003..2163707) Cronobacter sakazakii ATCC BAA-894 5551941 YP_001438314.1 CDS ESA_02229 NC_009778.1 2163700 2164899 R part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC complement(2163700..2164899) Cronobacter sakazakii ATCC BAA-894 5550306 YP_001438315.1 CDS ESA_02230 NC_009778.1 2165040 2168486 D KEGG: eci:UTI89_C1242 0. mfd; transcription-repair coupling factor; mutation frequency decline K03723; COG: COG1197 Transcription-repair coupling factor (superfamily II helicase); Psort location: cytoplasmic, score: 23; transcription-repair coupling factor 2165040..2168486 Cronobacter sakazakii ATCC BAA-894 5551837 YP_001438316.1 CDS ESA_02231 NC_009778.1 2168621 2169595 D KEGG: eci:UTI89_C2228 2.1e-74 erfK; hypothetical protein K00257; COG: COG1376 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2168621..2169595 Cronobacter sakazakii ATCC BAA-894 5551842 YP_001438317.1 CDS ESA_02232 NC_009778.1 2169650 2169907 R COG: NOG13874 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2169650..2169907) Cronobacter sakazakii ATCC BAA-894 5551815 YP_001438318.1 CDS ESA_02233 NC_009778.1 2170090 2170788 D COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 2170090..2170788 Cronobacter sakazakii ATCC BAA-894 5551855 YP_001438319.1 CDS ESA_02234 NC_009778.1 2171431 2171958 R COG: COG3134 Predicted outer membrane lipoprotein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2171431..2171958) Cronobacter sakazakii ATCC BAA-894 5551873 YP_001438320.1 CDS ESA_02235 NC_009778.1 2172155 2173459 R KEGG: stt:t1709 1.2e-215 ndh; NADH dehydrogenase K03885; COG: COG1252 NADH dehydrogenase, FAD-containing subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2172155..2173459) Cronobacter sakazakii ATCC BAA-894 5551872 YP_001438321.1 CDS ESA_02236 NC_009778.1 2173696 2174310 R COG: COG3150 Predicted esterase; Psort location: mitochondrial, score: 23; hypothetical protein complement(2173696..2174310) Cronobacter sakazakii ATCC BAA-894 5551869 YP_001438322.1 CDS ESA_02237 NC_009778.1 2174276 2175301 R hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase complement(2174276..2175301) Cronobacter sakazakii ATCC BAA-894 5551819 YP_001438323.1 CDS thiK NC_009778.1 2175319 2176137 R catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase complement(2175319..2176137) Cronobacter sakazakii ATCC BAA-894 5551828 YP_001438324.1 CDS ESA_02239 NC_009778.1 2176115 2176780 R KEGG: sco:SCO1554 0.0025 SCL11.10c; putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase K04719; COG: COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family); Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2176115..2176780) Cronobacter sakazakii ATCC BAA-894 5551856 YP_001438325.1 CDS ESA_02240 NC_009778.1 2176789 2177163 R COG: COG5633 Predicted periplasmic lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2176789..2177163) Cronobacter sakazakii ATCC BAA-894 5551822 YP_001438326.1 CDS ESA_02241 NC_009778.1 2177165 2177524 R KEGG: eci:UTI89_C1231 1.4e-54 ycfF; HIT-like protein YcfF K01518; COG: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2177165..2177524) Cronobacter sakazakii ATCC BAA-894 5551833 YP_001438327.1 CDS ESA_02242 NC_009778.1 2177871 2180072 D COG: COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid; Psort location: extracellular, including cell wall, score: 9; ferric-rhodotorulic acid outer membrane transporter 2177871..2180072 Cronobacter sakazakii ATCC BAA-894 5551832 YP_001438328.1 CDS ESA_02243 NC_009778.1 2180250 2181683 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC complement(2180250..2181683) Cronobacter sakazakii ATCC BAA-894 5551794 YP_001438329.1 CDS ESA_02244 NC_009778.1 2181982 2182776 R KEGG: eco:b1100 6.4e-121 ycfH; hypothetical protein K03424; COG: COG0084 Mg-dependent DNase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2181982..2182776) Cronobacter sakazakii ATCC BAA-894 5551805 YP_001438330.1 CDS ESA_02245 NC_009778.1 2182787 2183794 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(2182787..2183794) Cronobacter sakazakii ATCC BAA-894 5551839 YP_001438331.1 CDS tmk NC_009778.1 2183794 2184432 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(2183794..2184432) Cronobacter sakazakii ATCC BAA-894 5551845 YP_001438332.1 CDS ESA_02247 NC_009778.1 2184422 2185444 R KEGG: eco:b1097 2.9e-150 yceG; predicted aminodeoxychorismate lyase; COG: COG1559 Predicted periplasmic solute-binding protein; Psort location: extracellular, including cell wall, score: 23; hypothetical protein complement(2184422..2185444) Cronobacter sakazakii ATCC BAA-894 5551802 YP_001438333.1 CDS ESA_02248 NC_009778.1 2185455 2186255 R KEGG: sec:SC1148 8.8e-85 pabC; 4-amino-4-deoxychorismate lyase K02619; COG: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2185455..2186255) Cronobacter sakazakii ATCC BAA-894 5551777 YP_001438334.1 CDS ESA_02249 NC_009778.1 2186364 2187569 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(2186364..2187569) Cronobacter sakazakii ATCC BAA-894 5551810 YP_001438336.1 CDS acpP NC_009778.1 2187698 2187934 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(2187698..2187934) Cronobacter sakazakii ATCC BAA-894 5551779 YP_001438337.1 CDS fabG NC_009778.1 2188089 2188823 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase complement(2188089..2188823) Cronobacter sakazakii ATCC BAA-894 5551786 YP_001438338.1 CDS ESA_02253 NC_009778.1 2188837 2189766 R KEGG: stm:STM1194 8.1e-146 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase K00645; COG: COG0331 (acyl-carrier-protein) S-malonyltransferase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2188837..2189766) Cronobacter sakazakii ATCC BAA-894 5551768 YP_001438339.1 CDS ESA_02254 NC_009778.1 2189784 2190737 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III complement(2189784..2190737) Cronobacter sakazakii ATCC BAA-894 5551744 YP_001438340.1 CDS ESA_02255 NC_009778.1 2190744 2191748 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX complement(2190744..2191748) Cronobacter sakazakii ATCC BAA-894 5551741 YP_001438341.1 CDS rpmF NC_009778.1 2191851 2192024 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(2191851..2192024) Cronobacter sakazakii ATCC BAA-894 5551763 YP_001438342.1 CDS ESA_02257 NC_009778.1 2192076 2192597 R COG: COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2192076..2192597) Cronobacter sakazakii ATCC BAA-894 5551756 YP_001438343.1 CDS ESA_02258 NC_009778.1 2192738 2193325 D COG: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2192738..2193325 Cronobacter sakazakii ATCC BAA-894 5551740 YP_001438344.1 CDS ESA_02259 NC_009778.1 2193383 2194111 R KEGG: sag:SAG0445 0.0082 valS; valyl-tRNA synthetase K01873; COG: NOG06217 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(2193383..2194111) Cronobacter sakazakii ATCC BAA-894 5551771 YP_001438345.1 CDS ESA_02260 NC_009778.1 2194224 2195177 R catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C complement(2194224..2195177) Cronobacter sakazakii ATCC BAA-894 5551760 YP_001438346.1 CDS rne NC_009778.1 2195745 2198921 D bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 2195745..2198921 Cronobacter sakazakii ATCC BAA-894 5551694 YP_001438347.1 CDS ESA_02263 NC_009778.1 2198961 2199962 R KEGG: shn:Shewana3_3435 3.7e-10 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2198961..2199962) Cronobacter sakazakii ATCC BAA-894 5551670 YP_001438348.1 CDS ESA_02262 NC_009778.1 2199961 2201265 D KEGG: shn:Shewana3_1692 2.2e-08 Xaa-His dipeptidase K01270; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 2199961..2201265 Cronobacter sakazakii ATCC BAA-894 5551702 YP_001438349.1 CDS flgL NC_009778.1 2201347 2202291 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL complement(2201347..2202291) Cronobacter sakazakii ATCC BAA-894 5551722 YP_001438350.1 CDS flgK NC_009778.1 2202324 2203982 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(2202324..2203982) Cronobacter sakazakii ATCC BAA-894 5551703 YP_001438351.1 CDS flgJ NC_009778.1 2204058 2205023 R Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ complement(2204058..2205023) Cronobacter sakazakii ATCC BAA-894 5551730 YP_001438352.1 CDS flgI NC_009778.1 2205023 2206120 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(2205023..2206120) Cronobacter sakazakii ATCC BAA-894 5551716 YP_001438353.1 CDS flgH NC_009778.1 2206133 2206840 R part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein complement(2206133..2206840) Cronobacter sakazakii ATCC BAA-894 5551698 YP_001438354.1 CDS flgG NC_009778.1 2206888 2207670 R makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG complement(2206888..2207670) Cronobacter sakazakii ATCC BAA-894 5551719 YP_001438355.1 CDS flgF NC_009778.1 2207687 2208445 R FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF complement(2207687..2208445) Cronobacter sakazakii ATCC BAA-894 5551701 YP_001438356.1 CDS flgE NC_009778.1 2208466 2209695 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(2208466..2209695) Cronobacter sakazakii ATCC BAA-894 5551711 YP_001438357.1 CDS flgD NC_009778.1 2209722 2210402 R acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein complement(2209722..2210402) Cronobacter sakazakii ATCC BAA-894 5551647 YP_001438358.1 CDS flgC NC_009778.1 2210414 2210818 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(2210414..2210818) Cronobacter sakazakii ATCC BAA-894 5551690 YP_001438359.1 CDS flgB NC_009778.1 2210832 2211245 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB complement(2210832..2211245) Cronobacter sakazakii ATCC BAA-894 5551601 YP_001438360.1 CDS flgA NC_009778.1 2211399 2212058 D required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 2211399..2212058 Cronobacter sakazakii ATCC BAA-894 5551679 YP_001438361.1 CDS ESA_02276 NC_009778.1 2212140 2212448 D regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM 2212140..2212448 Cronobacter sakazakii ATCC BAA-894 5551645 YP_001438362.1 CDS ESA_02277 NC_009778.1 2212452 2212877 D COG: COG3418 Flagellar biosynthesis/type III secretory pathway chaperone; Psort location: nuclear, score: 23; hypothetical protein 2212452..2212877 Cronobacter sakazakii ATCC BAA-894 5551640 YP_001438363.1 CDS ESA_02278 NC_009778.1 2213035 2214570 R COG: COG0728 Uncharacterized membrane protein, putative virulence factor; Psort location: plasma membrane, score: 23; hypothetical protein complement(2213035..2214570) Cronobacter sakazakii ATCC BAA-894 5551668 YP_001438364.1 CDS ESA_02279 NC_009778.1 2214686 2215609 R KEGG: lpl:lp_0813 1.0e-33 oxidoreductase (putative) K03810; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2214686..2215609) Cronobacter sakazakii ATCC BAA-894 5551654 YP_001438365.1 CDS ESA_02280 NC_009778.1 2215612 2216265 R COG: COG3132 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2215612..2216265) Cronobacter sakazakii ATCC BAA-894 5551674 YP_001438366.1 CDS ESA_02282 NC_009778.1 2216276 2216860 R KEGG: ece:Z1703 9.0e-99 rimJ; acetylation of N-terminal alanine of 30S ribosomal subunit protein S5 K03790; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; ribosomal-protein-S5-alanine N-acetyltransferase complement(2216276..2216860) Cronobacter sakazakii ATCC BAA-894 5551643 YP_001438367.1 CDS ESA_02281 NC_009778.1 2216818 2217030 D Psort location: nuclear, score: 23; hypothetical protein 2216818..2217030 Cronobacter sakazakii ATCC BAA-894 5551629 YP_001438368.1 CDS ESA_02283 NC_009778.1 2217127 2218335 D Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 2217127..2218335 Cronobacter sakazakii ATCC BAA-894 5551631 YP_001438369.1 CDS ESA_02284 NC_009778.1 2218458 2219057 D cofactor involved in the reduction of disulfides; glutaredoxin 2 2218458..2219057 Cronobacter sakazakii ATCC BAA-894 5551625 YP_001438370.1 CDS ESA_02285 NC_009778.1 2219176 2219736 D COG: NOG07875 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2219176..2219736 Cronobacter sakazakii ATCC BAA-894 5551622 YP_001438371.1 CDS ESA_02286 NC_009778.1 2219865 2220911 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 2219865..2220911 Cronobacter sakazakii ATCC BAA-894 5551627 YP_001438372.1 CDS ESA_02287 NC_009778.1 2220998 2221243 D Psort location: cytoplasmic, score: 23; hypothetical protein 2220998..2221243 Cronobacter sakazakii ATCC BAA-894 5551617 YP_001438373.1 CDS bssS NC_009778.1 2221566 2221820 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 2221566..2221820 Cronobacter sakazakii ATCC BAA-894 5551603 YP_001438374.1 CDS solA NC_009778.1 2221938 2223062 D catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 2221938..2223062 Cronobacter sakazakii ATCC BAA-894 5551610 YP_001438375.1 CDS ESA_02290 NC_009778.1 2223445 2223939 D KEGG: reh:H16_A3123 2.2e-24 cytochrome b561 K00156; COG: COG3038 Cytochrome B561; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2223445..2223939 Cronobacter sakazakii ATCC BAA-894 5551573 YP_001438376.1 CDS ESA_02291 NC_009778.1 2223942 2224529 D COG: COG2353 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2223942..2224529 Cronobacter sakazakii ATCC BAA-894 5551602 YP_001438377.1 CDS ESA_02292 NC_009778.1 2224585 2225634 R KEGG: pub:SAR11_1074 1.4e-22 yceA; rhodanese domain protein; COG: COG1054 Predicted sulfurtransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2224585..2225634) Cronobacter sakazakii ATCC BAA-894 5552162 YP_001438378.1 CDS ESA_02293 NC_009778.1 2225860 2226780 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 2225860..2226780 Cronobacter sakazakii ATCC BAA-894 5551607 YP_001438379.1 CDS ESA_02294 NC_009778.1 2226911 2227288 D COG: NOG09842 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2226911..2227288 Cronobacter sakazakii ATCC BAA-894 5551595 YP_001438380.1 CDS ESA_02295 NC_009778.1 2227292 2227519 R COG: COG5645 Predicted periplasmic lipoprotein; Psort location: extracellular, including cell wall, score: 23; hypothetical protein complement(2227292..2227519) Cronobacter sakazakii ATCC BAA-894 5551604 YP_001438381.1 CDS ESA_02296 NC_009778.1 2227627 2230155 R necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH complement(2227627..2230155) Cronobacter sakazakii ATCC BAA-894 5551569 YP_001438382.1 CDS mdoG NC_009778.1 2230148 2231701 R involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G complement(2230148..2231701) Cronobacter sakazakii ATCC BAA-894 5551599 YP_001438383.1 CDS mdoC NC_009778.1 2231957 2233114 D required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 2231957..2233114 Cronobacter sakazakii ATCC BAA-894 5551496 YP_001438384.1 CDS ESA_02299 NC_009778.1 2233145 2234449 R KEGG: reh:H16_B1107 4.6e-111 phospholipase D K01115; COG: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2233145..2234449) Cronobacter sakazakii ATCC BAA-894 5551568 YP_001438385.1 CDS ESA_02300 NC_009778.1 2234565 2235107 R KEGG: reh:H16_A1552 3.0e-45 predicted phosphatase homolog to the C-terminal domain of histone macroH2A1; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2234565..2235107) Cronobacter sakazakii ATCC BAA-894 5551582 YP_001438386.1 CDS ESA_02301 NC_009778.1 2235687 2236163 R KEGG: abo:ABO_0612 0.0079 pilD; Leaderpeptidase and N-methyltransferase K02654; COG: NOG09737 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2235687..2236163) Cronobacter sakazakii ATCC BAA-894 5551534 YP_001438387.1 CDS ESA_02302 NC_009778.1 2236274 2236840 R KEGG: vfi:VFA0083 3.5e-07 ynfI; anaerobic dimethyl sulfoxide reductase chain YnfI K00397; COG: COG3381 Uncharacterized component of anaerobic dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2236274..2236840) Cronobacter sakazakii ATCC BAA-894 5551558 YP_001438388.1 CDS ESA_02303 NC_009778.1 2236865 2237239 R KEGG: eci:UTI89_C1155 3.0e-45 ycdX; hypothetical protein K04477; COG: COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2236865..2237239) Cronobacter sakazakii ATCC BAA-894 5551532 YP_001438389.1 CDS ESA_02304 NC_009778.1 2237406 2237729 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2237406..2237729) Cronobacter sakazakii ATCC BAA-894 5551544 YP_001438390.1 CDS ESA_02305 NC_009778.1 2238106 2238267 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2238106..2238267) Cronobacter sakazakii ATCC BAA-894 5551507 YP_001438391.1 CDS ESA_02306 NC_009778.1 2238282 2238584 R Psort location: plasma membrane, score: 23; hypothetical protein complement(2238282..2238584) Cronobacter sakazakii ATCC BAA-894 5551475 YP_001438392.1 CDS ESA_02307 NC_009778.1 2238913 2239488 R Psort location: nuclear, score: 23; hypothetical protein complement(2238913..2239488) Cronobacter sakazakii ATCC BAA-894 5551509 YP_001438393.1 CDS ESA_02308 NC_009778.1 2239531 2239962 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2239531..2239962) Cronobacter sakazakii ATCC BAA-894 5551473 YP_001438394.1 CDS ESA_02309 NC_009778.1 2240059 2240448 D KEGG: bam:Bamb_4258 1.9e-09 lysozyme K01185; COG: NOG21649 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2240059..2240448 Cronobacter sakazakii ATCC BAA-894 5551491 YP_001438395.1 CDS ESA_02310 NC_009778.1 2240489 2240758 R KEGG: fnu:FN0522 0.0070 exonuclease SBCC K03546; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2240489..2240758) Cronobacter sakazakii ATCC BAA-894 5551462 YP_001438396.1 CDS ESA_02311 NC_009778.1 2240805 2243903 R COG: COG4733 Phage-related protein, tail component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2240805..2243903) Cronobacter sakazakii ATCC BAA-894 5551456 YP_001438397.1 CDS ESA_02312 NC_009778.1 2245384 2245938 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2245384..2245938) Cronobacter sakazakii ATCC BAA-894 5551485 YP_001438398.1 CDS ESA_02313 NC_009778.1 2245990 2248428 R KEGG: nma:NMA0905 6.3e-06 iga; IgA1 protease K01347; COG: COG5281 Phage-related minor tail protein; Psort location: nuclear, score: 23; hypothetical protein complement(2245990..2248428) Cronobacter sakazakii ATCC BAA-894 5551468 YP_001438399.1 CDS ESA_02314 NC_009778.1 2248436 2248732 R Psort location: nuclear, score: 23; hypothetical protein complement(2248436..2248732) Cronobacter sakazakii ATCC BAA-894 5551472 YP_001438400.1 CDS ESA_02315 NC_009778.1 2249147 2249653 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2249147..2249653) Cronobacter sakazakii ATCC BAA-894 5551452 YP_001438401.1 CDS ESA_02316 NC_009778.1 2249677 2252499 R COG: NOG31760 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2249677..2252499) Cronobacter sakazakii ATCC BAA-894 5551435 YP_001438402.1 CDS ESA_02317 NC_009778.1 2252496 2254187 R KEGG: chu:CHU_0597 0.00010 CHU large protein; uncharacterized K01238; COG: COG3210 Large exoproteins involved in heme utilization or adhesion; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2252496..2254187) Cronobacter sakazakii ATCC BAA-894 5551409 YP_001438403.1 CDS ESA_02318 NC_009778.1 2254629 2254928 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2254629..2254928) Cronobacter sakazakii ATCC BAA-894 5552038 YP_001438404.1 CDS ESA_02319 NC_009778.1 2254940 2256328 R KEGG: ddi:DDB0191487 3.3e-06 kinX; LISK family protein kinase K05743; COG: COG1340 Uncharacterized archaeal coiled-coil protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2254940..2256328) Cronobacter sakazakii ATCC BAA-894 5551420 YP_001438405.1 CDS ESA_02320 NC_009778.1 2256804 2258324 R COG: COG5511 Bacteriophage capsid protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2256804..2258324) Cronobacter sakazakii ATCC BAA-894 5551382 YP_001438406.1 CDS ESA_02321 NC_009778.1 2258819 2259778 R COG: COG5525 Bacteriophage tail assembly protein; Psort location: nuclear, score: 23; hypothetical protein complement(2258819..2259778) Cronobacter sakazakii ATCC BAA-894 5552444 YP_001438407.1 CDS ESA_02322 NC_009778.1 2259908 2260105 D Psort location: cytoplasmic, score: 23; hypothetical protein 2259908..2260105 Cronobacter sakazakii ATCC BAA-894 5551416 YP_001438408.1 CDS ESA_02323 NC_009778.1 2260650 2261195 R KEGG: cal:orf19.2410 0.0056 IMH1; involved in vesicular transport K01553; Psort location: nuclear, score: 23; hypothetical protein complement(2260650..2261195) Cronobacter sakazakii ATCC BAA-894 5551408 YP_001438409.1 CDS ESA_02324 NC_009778.1 2261353 2262015 D COG: NOG30563 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2261353..2262015 Cronobacter sakazakii ATCC BAA-894 5551329 YP_001438410.1 CDS ESA_02325 NC_009778.1 2262015 2262452 D COG: NOG13962 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2262015..2262452 Cronobacter sakazakii ATCC BAA-894 5551386 YP_001438411.1 CDS ESA_02326 NC_009778.1 2262449 2263039 D Psort location: cytoplasmic, score: 23; hypothetical protein 2262449..2263039 Cronobacter sakazakii ATCC BAA-894 5551343 YP_001438412.1 CDS ESA_02327 NC_009778.1 2263063 2263737 R KEGG: vfi:VF0494 8.8e-05 sensory transduction protein kinase; COG: COG2200 FOG: EAL domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2263063..2263737) Cronobacter sakazakii ATCC BAA-894 5551378 YP_001438413.1 CDS ESA_02328 NC_009778.1 2263924 2264238 D Psort location: cytoplasmic, score: 23; hypothetical protein 2263924..2264238 Cronobacter sakazakii ATCC BAA-894 5552329 YP_001438414.1 CDS ESA_02329 NC_009778.1 2264270 2264731 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2264270..2264731) Cronobacter sakazakii ATCC BAA-894 5551380 YP_001438415.1 CDS ESA_02330 NC_009778.1 2264736 2265020 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2264736..2265020) Cronobacter sakazakii ATCC BAA-894 5551360 YP_001438416.1 CDS ESA_02331 NC_009778.1 2265233 2265910 R Psort location: nuclear, score: 23; hypothetical protein complement(2265233..2265910) Cronobacter sakazakii ATCC BAA-894 5551354 YP_001438417.1 CDS ESA_02332 NC_009778.1 2266359 2266634 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2266359..2266634) Cronobacter sakazakii ATCC BAA-894 5551340 YP_001438418.1 CDS ESA_02334 NC_009778.1 2266716 2266973 R Psort location: nuclear, score: 23; hypothetical protein complement(2266716..2266973) Cronobacter sakazakii ATCC BAA-894 5551362 YP_001438419.1 CDS ESA_02333 NC_009778.1 2266839 2266985 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2266839..2266985 Cronobacter sakazakii ATCC BAA-894 5551336 YP_001438420.1 CDS ESA_02335 NC_009778.1 2267037 2267366 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2267037..2267366) Cronobacter sakazakii ATCC BAA-894 5551338 YP_001438421.1 CDS ESA_02336 NC_009778.1 2267960 2270029 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2267960..2270029) Cronobacter sakazakii ATCC BAA-894 5551348 YP_001438422.1 CDS ESA_02337 NC_009778.1 2270117 2270350 R KEGG: msu:MS0629 0.0094 surA; parvulin-like peptidyl-prolyl isomerase K03771; Psort location: nuclear, score: 23; hypothetical protein complement(2270117..2270350) Cronobacter sakazakii ATCC BAA-894 5551330 YP_001438423.1 CDS ESA_02338 NC_009778.1 2270579 2270764 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2270579..2270764) Cronobacter sakazakii ATCC BAA-894 5551303 YP_001438424.1 CDS ESA_02339 NC_009778.1 2270858 2272660 R COG: COG1961 Site-specific recombinases, DNA invertase Pin homologs; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2270858..2272660) Cronobacter sakazakii ATCC BAA-894 5551279 YP_001438425.1 CDS ESA_02340 NC_009778.1 2272695 2273147 R KEGG: eci:UTI89_C1155 7.6e-63 ycdX; hypothetical protein K04477; COG: COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2272695..2273147) Cronobacter sakazakii ATCC BAA-894 5551315 YP_001438426.1 CDS ESA_02341 NC_009778.1 2273193 2274134 R KEGG: eco:b1033 2.1e-115 ycdW; 2-ketoacid reductase K00049; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2273193..2274134) Cronobacter sakazakii ATCC BAA-894 5551295 YP_001438427.1 CDS ESA_02342 NC_009778.1 2274220 2275248 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2274220..2275248) Cronobacter sakazakii ATCC BAA-894 5551306 YP_001438428.1 CDS ESA_02343 NC_009778.1 2275264 2277804 R COG: COG3188 P pilus assembly protein, porin PapC; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2275264..2277804) Cronobacter sakazakii ATCC BAA-894 5551253 YP_001438429.1 CDS ESA_02344 NC_009778.1 2277844 2278518 R COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2277844..2278518) Cronobacter sakazakii ATCC BAA-894 5551269 YP_001438430.1 CDS ESA_02345 NC_009778.1 2278598 2279206 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2278598..2279206) Cronobacter sakazakii ATCC BAA-894 5551281 YP_001438431.1 CDS ESA_02347 NC_009778.1 2280213 2282561 R KEGG: bur:Bcep18194_C6997 7.9e-258 oxidoreductase alpha (molybdopterin) subunit K00122; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2280213..2282561) Cronobacter sakazakii ATCC BAA-894 5551244 YP_001438432.1 CDS ESA_02349 NC_009778.1 2283254 2283928 R KEGG: reh:H16_A0527 8.1e-43 phoH; phosphate starvation-inducible protein PhoH,predicted ATPase; COG: COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2283254..2283928) Cronobacter sakazakii ATCC BAA-894 5551224 YP_001438433.1 CDS ESA_02350 NC_009778.1 2284583 2285866 R KEGG: reh:H16_B0946 7.0e-05 predicted iron-dependent peroxidase K00430; COG: COG2837 Predicted iron-dependent peroxidase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2284583..2285866) Cronobacter sakazakii ATCC BAA-894 5551213 YP_001438434.1 CDS ESA_02351 NC_009778.1 2285872 2287005 R COG: COG2822 Predicted periplasmic lipoprotein involved in iron transport; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2285872..2287005) Cronobacter sakazakii ATCC BAA-894 5551214 YP_001438435.1 CDS ESA_02352 NC_009778.1 2287055 2287885 R COG: COG0672 High-affinity Fe2+/Pb2+ permease; Psort location: plasma membrane, score: 23; hypothetical protein complement(2287055..2287885) Cronobacter sakazakii ATCC BAA-894 5552473 YP_001438436.1 CDS ESA_02353 NC_009778.1 2288243 2289427 D COG: COG1972 Nucleoside permease; Psort location: plasma membrane, score: 23; hypothetical protein 2288243..2289427 Cronobacter sakazakii ATCC BAA-894 5551183 YP_001438437.1 CDS ESA_02354 NC_009778.1 2289457 2289879 R COG: NOG18370 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2289457..2289879) Cronobacter sakazakii ATCC BAA-894 5551163 YP_001438438.1 CDS ESA_02355 NC_009778.1 2289997 2291487 R KEGG: rde:RD1_2839 1.7e-06 sensor histidine kinase, putative; COG: COG0591 Na+/proline symporter; Psort location: plasma membrane, score: 23; hypothetical protein complement(2289997..2291487) Cronobacter sakazakii ATCC BAA-894 5551146 YP_001438439.1 CDS ESA_02356 NC_009778.1 2291640 2291777 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2291640..2291777) Cronobacter sakazakii ATCC BAA-894 5551176 YP_001438440.1 CDS putA NC_009778.1 2291919 2295881 D proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 2291919..2295881 Cronobacter sakazakii ATCC BAA-894 5551142 YP_001438441.1 CDS ESA_02358 NC_009778.1 2295939 2296409 R COG: NOG26382 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2295939..2296409) Cronobacter sakazakii ATCC BAA-894 5551134 YP_001438442.1 CDS ESA_02359 NC_009778.1 2296406 2297248 R COG: NOG26268 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2296406..2297248) Cronobacter sakazakii ATCC BAA-894 5551184 YP_001438443.1 CDS ESA_02360 NC_009778.1 2297365 2298003 R KEGG: bcl:ABC2937 5.2e-05 NADH dehydrogenase K03885; COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2297365..2298003) Cronobacter sakazakii ATCC BAA-894 5551167 YP_001438444.1 CDS ESA_02362 NC_009778.1 2298117 2298356 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2298117..2298356) Cronobacter sakazakii ATCC BAA-894 5551161 YP_001438445.1 CDS ESA_02361 NC_009778.1 2298355 2299374 D KEGG: ecs:ECs1258 4.0e-167 hypothetical protein K09018; COG: COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; Psort location: cytoplasmic, score: 23; hypothetical protein 2298355..2299374 Cronobacter sakazakii ATCC BAA-894 5551162 YP_001438446.1 CDS ESA_02363 NC_009778.1 2299374 2300072 D KEGG: ssn:SSO_1030 3.1e-105 putative synthetase K09020; COG: COG1335 Amidases related to nicotinamidase; Psort location: cytoplasmic, score: 23; hypothetical protein 2299374..2300072 Cronobacter sakazakii ATCC BAA-894 5551168 YP_001438447.1 CDS ESA_02364 NC_009778.1 2300082 2300480 D KEGG: ape:APE_1501.1 2.2e-10 ribonuclease UK114; COG: COG0251 Putative translation initiation inhibitor, yjgF family; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2300082..2300480 Cronobacter sakazakii ATCC BAA-894 5551147 YP_001438448.1 CDS ESA_02365 NC_009778.1 2300477 2301283 D KEGG: pae:PA0480 4.5e-17 putative beta-ketoadipate enol-lactone hydrolase K01055; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein 2300477..2301283 Cronobacter sakazakii ATCC BAA-894 5551140 YP_001438449.1 CDS ESA_02366 NC_009778.1 2301280 2301870 D KEGG: ecs:ECs1254 6.3e-75 putative enzyme K09019; COG: COG0778 Nitroreductase; Psort location: cytoplasmic, score: 23; hypothetical protein 2301280..2301870 Cronobacter sakazakii ATCC BAA-894 5551143 YP_001438450.1 CDS ESA_02367 NC_009778.1 2301880 2302380 D KEGG: ecc:c1144 2.6e-62 ycdH; putative flavin:NADH reductase YcdH K09024; COG: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; Psort location: cytoplasmic, score: 23; hypothetical protein 2301880..2302380 Cronobacter sakazakii ATCC BAA-894 5551144 YP_001438451.1 CDS ESA_02368 NC_009778.1 2302398 2303735 D KEGG: bcz:BCZK0244 2.3e-10 guanine-hypoxanTHIne permease; xanTHIne/uracil permease family protein K06901; COG: COG2233 XanTHIne/uracil permeases; Psort location: plasma membrane, score: 23; hypothetical protein 2302398..2303735 Cronobacter sakazakii ATCC BAA-894 5551145 YP_001438452.1 CDS ESA_02369 NC_009778.1 2303798 2303980 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2303798..2303980) Cronobacter sakazakii ATCC BAA-894 5551122 YP_001438453.1 CDS ESA_02370 NC_009778.1 2304342 2304989 D KEGG: mav:MAV_3849 6.3e-27 wrbA; NAD(P)H:quinone oxidoreductase, type IV K00355; COG: COG0655 Multimeric flavodoxin WrbA; Psort location: cytoplasmic, score: 23; hypothetical protein 2304342..2304989 Cronobacter sakazakii ATCC BAA-894 5551109 YP_001438454.1 CDS ESA_02371 NC_009778.1 2305015 2305242 D COG: NOG13872 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2305015..2305242 Cronobacter sakazakii ATCC BAA-894 5551095 YP_001438455.1 CDS ESA_02372 NC_009778.1 2305278 2306234 R KEGG: sus:Acid_6874 8.1e-43 beta-lactamase K01467; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2305278..2306234) Cronobacter sakazakii ATCC BAA-894 5551117 YP_001438456.1 CDS ESA_02373 NC_009778.1 2306238 2307140 D COG: NOG25608 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2306238..2307140 Cronobacter sakazakii ATCC BAA-894 5551108 YP_001438457.1 CDS ESA_02374 NC_009778.1 2307305 2308642 R COG: COG3515 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2307305..2308642) Cronobacter sakazakii ATCC BAA-894 5551100 YP_001438458.1 CDS ESA_02375 NC_009778.1 2308666 2309124 R COG: COG3518 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2308666..2309124) Cronobacter sakazakii ATCC BAA-894 5551076 YP_001438459.1 CDS ESA_02376 NC_009778.1 2309153 2310739 R COG: COG3515 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2309153..2310739) Cronobacter sakazakii ATCC BAA-894 5551101 YP_001438460.1 CDS ESA_02378 NC_009778.1 2311282 2312907 R KEGG: shn:Shewana3_2650 1.2e-30 acetate kinase K00925; COG: COG4166 ABC-type oligopeptide transport system, periplasmic component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2311282..2312907) Cronobacter sakazakii ATCC BAA-894 5551057 YP_001438461.1 CDS ESA_02379 NC_009778.1 2313167 2313826 D COG: COG0670 Integral membrane protein, interacts with FtsH; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2313167..2313826 Cronobacter sakazakii ATCC BAA-894 5551068 YP_001438462.1 CDS ESA_02380 NC_009778.1 2313934 2314263 D transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 2313934..2314263 Cronobacter sakazakii ATCC BAA-894 5551056 YP_001438463.1 CDS ESA_02381 NC_009778.1 2314260 2314523 R KEGG: stm:STM1083 4.0e-34 yccX; putative phosphohydrolase K01512; COG: COG1254 Acylphosphatases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2314260..2314523) Cronobacter sakazakii ATCC BAA-894 5551059 YP_001438464.1 CDS ESA_02382 NC_009778.1 2314630 2315820 D KEGG: eci:UTI89_C1034 2.1e-193 yccW; hypothetical protein YccW K06969; COG: COG1092 Predicted SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 2314630..2315820 Cronobacter sakazakii ATCC BAA-894 5551050 YP_001438465.1 CDS ESA_02383 NC_009778.1 2315832 2316197 D COG: COG3785 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; heat shock protein HspQ 2315832..2316197 Cronobacter sakazakii ATCC BAA-894 5551063 YP_001438466.1 CDS ESA_02384 NC_009778.1 2316231 2316638 R KEGG: rru:Rru_A2075 1.3e-30 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; COG: COG1832 Predicted CoA-binding protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2316231..2316638) Cronobacter sakazakii ATCC BAA-894 5552346 YP_001438467.1 CDS mgsA NC_009778.1 2316799 2317257 D catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 2316799..2317257 Cronobacter sakazakii ATCC BAA-894 5551043 YP_001438468.1 CDS helD NC_009778.1 2317259 2319313 R catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV complement(2317259..2319313) Cronobacter sakazakii ATCC BAA-894 5551028 YP_001438469.1 CDS ESA_02387 NC_009778.1 2319440 2319886 D COG: COG3304 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2319440..2319886 Cronobacter sakazakii ATCC BAA-894 5551047 YP_001438470.1 CDS ESA_02388 NC_009778.1 2319901 2322036 D KEGG: eco:b3358 3.9e-29 yhfK; conserved inner membrane protein K01823; COG: COG1289 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein 2319901..2322036 Cronobacter sakazakii ATCC BAA-894 5551031 YP_001438471.1 CDS ESA_02389 NC_009778.1 2322027 2322641 R COG: COG3070 Regulator of competence-specific genes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2322027..2322641) Cronobacter sakazakii ATCC BAA-894 5551024 YP_001438472.1 CDS ESA_02390 NC_009778.1 2322859 2323365 D COG: COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation; Psort location: nuclear, score: 23; SOS cell division inhibitor 2322859..2323365 Cronobacter sakazakii ATCC BAA-894 5552296 YP_001438473.1 CDS ESA_02391 NC_009778.1 2323689 2324765 D OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 2323689..2324765 Cronobacter sakazakii ATCC BAA-894 5550984 YP_001438474.1 CDS ESA_02392 NC_009778.1 2324936 2325391 R COG: COG3120 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2324936..2325391) Cronobacter sakazakii ATCC BAA-894 5551008 YP_001438475.1 CDS ESA_02393 NC_009778.1 2325647 2327332 D KEGG: ecp:ECP_0960 5.8e-207 putative protease La K04770; COG: COG1067 Predicted ATP-dependent protease; Psort location: cytoplasmic, score: 23; hypothetical protein 2325647..2327332 Cronobacter sakazakii ATCC BAA-894 5551012 YP_001438476.1 CDS ESA_02394 NC_009778.1 2327401 2327919 D catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-(acyl carrier protein) dehydratase 2327401..2327919 Cronobacter sakazakii ATCC BAA-894 5550955 YP_001438477.1 CDS ESA_02395 NC_009778.1 2328411 2328974 R COG: COG3009 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2328411..2328974) Cronobacter sakazakii ATCC BAA-894 5551017 YP_001438478.1 CDS ESA_02396 NC_009778.1 2328971 2330611 R COG: COG3008 Paraquat-inducible protein B; Psort location: mitochondrial, score: 23; paraquat-inducible protein B complement(2328971..2330611) Cronobacter sakazakii ATCC BAA-894 5550989 YP_001438479.1 CDS ESA_02397 NC_009778.1 2330601 2331839 R COG: COG2995 Uncharacterized paraquat-inducible protein A; Psort location: plasma membrane, score: 23; hypothetical protein complement(2330601..2331839) Cronobacter sakazakii ATCC BAA-894 5551005 YP_001438480.1 CDS ESA_02398 NC_009778.1 2331886 2333790 R Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase component complement(2331886..2333790) Cronobacter sakazakii ATCC BAA-894 5550980 YP_001438481.1 CDS rlmL NC_009778.1 2333796 2335913 R catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase complement(2333796..2335913) Cronobacter sakazakii ATCC BAA-894 5550903 YP_001438482.1 CDS ESA_02400 NC_009778.1 2336016 2337122 D KEGG: eci:UTI89_C0875 1.2e-05 hcr; NADH oxidoreductase; COG: COG0633 Ferredoxin; Psort location: cytoplasmic, score: 23; hypothetical protein 2336016..2337122 Cronobacter sakazakii ATCC BAA-894 5550964 YP_001438483.1 CDS ESA_02401 NC_009778.1 2337119 2337664 R COG: NOG07913 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2337119..2337664) Cronobacter sakazakii ATCC BAA-894 5550972 YP_001438484.1 CDS ESA_02402 NC_009778.1 2337829 2338839 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(2337829..2338839) Cronobacter sakazakii ATCC BAA-894 5550948 YP_001438485.1 CDS ESA_02403 NC_009778.1 2339088 2339663 D KEGG: eco:b0937 2.2e-72 ssuE, suE, ycbP, ssi4; NAD(P)H-dependent FMN reductase K00299; COG: COG0431 Predicted flavoprotein; Psort location: mitochondrial, score: 23; NAD(P)H-dependent FMN reductase 2339088..2339663 Cronobacter sakazakii ATCC BAA-894 5550968 YP_001438486.1 CDS ESA_02404 NC_009778.1 2339656 2340627 D KEGG: mav:MAV_3808 0.0013 2'-hydroxybiphenyl-2-sulfinate desulfinase K05977; COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2339656..2340627 Cronobacter sakazakii ATCC BAA-894 5550961 YP_001438487.1 CDS ESA_02405 NC_009778.1 2340624 2341769 D catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 2340624..2341769 Cronobacter sakazakii ATCC BAA-894 5550934 YP_001438488.1 CDS ssuC NC_009778.1 2341779 2342570 D part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit 2341779..2342570 Cronobacter sakazakii ATCC BAA-894 5550950 YP_001438489.1 CDS ssuB NC_009778.1 2342567 2343334 D part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 2342567..2343334 Cronobacter sakazakii ATCC BAA-894 5550479 YP_001438490.1 CDS pepN NC_009778.1 2343608 2346220 R KEGG: stm:STM1057 0. pepN; aminopeptidase N K01256; COG: COG0308 Aminopeptidase N; Psort location: cytoplasmic, score: 23; aminopeptidase N complement(2343608..2346220) Cronobacter sakazakii ATCC BAA-894 5550941 YP_001438491.1 CDS ESA_02410 NC_009778.1 2346540 2346695 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2346540..2346695) Cronobacter sakazakii ATCC BAA-894 5550890 YP_001438492.1 CDS ESA_02409 NC_009778.1 2346694 2347896 D catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2346694..2347896 Cronobacter sakazakii ATCC BAA-894 5550831 YP_001438493.1 CDS asnC NC_009778.1 2348138 2349463 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 2348138..2349463 Cronobacter sakazakii ATCC BAA-894 5550921 YP_001438494.1 CDS ESA_02412 NC_009778.1 2349544 2349759 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2349544..2349759) Cronobacter sakazakii ATCC BAA-894 5550904 YP_001438495.1 CDS ESA_02413 NC_009778.1 2349998 2351098 D COG: COG3203 Outer membrane protein (porin); Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2349998..2351098 Cronobacter sakazakii ATCC BAA-894 5550880 YP_001438496.1 CDS ESA_02414 NC_009778.1 2351284 2352474 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 2351284..2352474 Cronobacter sakazakii ATCC BAA-894 5550900 YP_001438497.1 CDS ESA_02415 NC_009778.1 2352533 2353180 R KEGG: eci:UTI89_C0999 1.1e-104 ycbL; hypothetical protein K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2352533..2353180) Cronobacter sakazakii ATCC BAA-894 5550901 YP_001438498.1 CDS ESA_02416 NC_009778.1 2353219 2353854 R COG: COG3108 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2353219..2353854) Cronobacter sakazakii ATCC BAA-894 5550892 YP_001438499.1 CDS ESA_02417 NC_009778.1 2353947 2355941 R COG: COG2989 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2353947..2355941) Cronobacter sakazakii ATCC BAA-894 5550908 YP_001438500.1 CDS mukB NC_009778.1 2355910 2360358 R SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB complement(2355910..2360358) Cronobacter sakazakii ATCC BAA-894 5550863 YP_001438501.1 CDS ESA_02419 NC_009778.1 2360351 2361034 R acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E complement(2360351..2361034) Cronobacter sakazakii ATCC BAA-894 5550823 YP_001438502.1 CDS ESA_02420 NC_009778.1 2361042 2362364 R acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F complement(2361042..2362364) Cronobacter sakazakii ATCC BAA-894 5550853 YP_001438503.1 CDS ESA_02421 NC_009778.1 2362368 2363147 R involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA complement(2362368..2363147) Cronobacter sakazakii ATCC BAA-894 5550867 YP_001438504.1 CDS ESA_02422 NC_009778.1 2363280 2364059 D COG: COG1434 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2363280..2364059 Cronobacter sakazakii ATCC BAA-894 5550860 YP_001438505.1 CDS ESA_02423 NC_009778.1 2364036 2364929 R COG: NOG06195 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2364036..2364929) Cronobacter sakazakii ATCC BAA-894 5549713 YP_001438506.1 CDS ESA_02424 NC_009778.1 2365020 2365442 R COG: NOG14690 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2365020..2365442) Cronobacter sakazakii ATCC BAA-894 5550858 YP_001438507.1 CDS ESA_02425 NC_009778.1 2365569 2366048 D COG: COG1522 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 2365569..2366048 Cronobacter sakazakii ATCC BAA-894 5549762 YP_001438508.1 CDS ESA_02426 NC_009778.1 2366083 2366829 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(2366083..2366829) Cronobacter sakazakii ATCC BAA-894 5549469 YP_001438509.1 CDS ESA_02427 NC_009778.1 2366826 2367008 R KEGG: net:Neut_2110 1.2e-15 tetraacyldisaccharide 4'-kinase K00912; COG: COG2835 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2366826..2367008) Cronobacter sakazakii ATCC BAA-894 5549982 YP_001438510.1 CDS ESA_02428 NC_009778.1 2367034 2368293 R COG: COG3214 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2367034..2368293) Cronobacter sakazakii ATCC BAA-894 5549811 YP_001438511.1 CDS lpxK NC_009778.1 2368328 2369305 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(2368328..2369305) Cronobacter sakazakii ATCC BAA-894 5550032 YP_001438512.1 CDS ESA_02430 NC_009778.1 2369302 2371050 R involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease protein complement(2369302..2371050) Cronobacter sakazakii ATCC BAA-894 5550041 YP_001438513.1 CDS ESA_02431 NC_009778.1 2371087 2373312 R COG: COG0658 Predicted membrane metal-binding protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(2371087..2373312) Cronobacter sakazakii ATCC BAA-894 5549795 YP_001438514.1 CDS ihfB NC_009778.1 2373550 2373852 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(2373550..2373852) Cronobacter sakazakii ATCC BAA-894 5549784 YP_001438515.1 CDS rpsA NC_009778.1 2373949 2375622 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(2373949..2375622) Cronobacter sakazakii ATCC BAA-894 5549970 YP_001438516.1 CDS cmk NC_009778.1 2375734 2376441 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(2375734..2376441) Cronobacter sakazakii ATCC BAA-894 5550118 YP_001438517.1 CDS ESA_02434 NC_009778.1 2376395 2376601 D Psort location: cytoplasmic, score: 23; hypothetical protein 2376395..2376601 Cronobacter sakazakii ATCC BAA-894 5549664 YP_001438518.1 CDS ESA_02436 NC_009778.1 2376598 2377884 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(2376598..2377884) Cronobacter sakazakii ATCC BAA-894 5549780 YP_001438519.1 CDS ESA_02437 NC_009778.1 2377953 2379038 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(2377953..2379038) Cronobacter sakazakii ATCC BAA-894 5549822 YP_001438520.1 CDS ESA_02438 NC_009778.1 2379201 2379893 R KEGG: mmp:MMP0248 0.0028 DNA-directed RNA polymerase related protein K03059; COG: COG2323 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2379201..2379893) Cronobacter sakazakii ATCC BAA-894 5549743 YP_001438521.1 CDS ESA_02439 NC_009778.1 2380035 2381798 D COG: COG1944 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 2380035..2381798 Cronobacter sakazakii ATCC BAA-894 5549766 YP_001438522.1 CDS ESA_02440 NC_009778.1 2382244 2383059 D KEGG: shn:Shewana3_1556 2.1e-74 meTHIonine gamma-lyase K01761; COG: COG2116 Formate/nitrite family of transporters; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2382244..2383059 Cronobacter sakazakii ATCC BAA-894 5549812 YP_001438523.1 CDS ESA_02441 NC_009778.1 2383111 2385393 D KEGG: stm:STM0973 0. pflB; pyruvate formate lyase I K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: cytoplasmic, score: 23; hypothetical protein 2383111..2385393 Cronobacter sakazakii ATCC BAA-894 5549764 YP_001438524.1 CDS ESA_02442 NC_009778.1 2383132 2385483 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2383132..2385483) Cronobacter sakazakii ATCC BAA-894 5550145 YP_001438525.1 CDS pflA NC_009778.1 2385589 2386329 D activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 2385589..2386329 Cronobacter sakazakii ATCC BAA-894 5549992 YP_001438526.1 CDS ESA_02445 NC_009778.1 2386363 2387511 R KEGG: eci:UTI89_C5041 8.4e-07 yjiJ; hypothetical protein YjiJ K00403; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 23; putative MFS family transporter protein complement(2386363..2387511) Cronobacter sakazakii ATCC BAA-894 5550261 YP_001438527.1 CDS ESA_02444 NC_009778.1 2387510 2387689 D Psort location: cytoplasmic, score: 23; hypothetical protein 2387510..2387689 Cronobacter sakazakii ATCC BAA-894 5550239 YP_001438528.1 CDS ESA_02446 NC_009778.1 2387807 2389099 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(2387807..2389099) Cronobacter sakazakii ATCC BAA-894 5549597 YP_001438529.1 CDS ESA_02447 NC_009778.1 2389196 2390482 R KEGG: pha:PSHAa1714 4.9e-139 rarA; polynucleotide enzyme with nucleotide triphosphate hydrolase domain K07478; COG: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; Psort location: cytoplasmic, score: 23; recombination factor protein RarA complement(2389196..2390482) Cronobacter sakazakii ATCC BAA-894 5550187 YP_001438530.1 CDS lolA NC_009778.1 2390552 2391166 R participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein complement(2390552..2391166) Cronobacter sakazakii ATCC BAA-894 5549778 YP_001438531.1 CDS ESA_02449 NC_009778.1 2391356 2395507 R KEGG: pen:PSEEN2212 1.7e-186 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2391356..2395507) Cronobacter sakazakii ATCC BAA-894 5549447 YP_001438532.1 CDS ESA_02450 NC_009778.1 2395627 2396160 R mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator complement(2395627..2396160) Cronobacter sakazakii ATCC BAA-894 5549657 YP_001438533.1 CDS ESA_02451 NC_009778.1 2396591 2397559 D catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 2396591..2397559 Cronobacter sakazakii ATCC BAA-894 5549613 YP_001438534.1 CDS ESA_02452 NC_009778.1 2397675 2399441 D in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 2397675..2399441 Cronobacter sakazakii ATCC BAA-894 5549468 YP_001438535.1 CDS ESA_02453 NC_009778.1 2399442 2401175 D in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 2399442..2401175 Cronobacter sakazakii ATCC BAA-894 5549528 YP_001438536.1 CDS ESA_02454 NC_009778.1 2401327 2401917 D KEGG: spt:SPA1843 7.9e-84 aat; leucyl/phenylalanyl-tRNA-protein transferase K00684; COG: COG2360 Leu/Phe-tRNA-protein transferase; Psort location: cytoplasmic, score: 23; hypothetical protein 2401327..2401917 Cronobacter sakazakii ATCC BAA-894 5551615 YP_001438537.1 CDS infA NC_009778.1 2402193 2402411 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2402193..2402411 Cronobacter sakazakii ATCC BAA-894 5552070 YP_001438538.1 CDS clpA NC_009778.1 2402579 2404852 R ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit complement(2402579..2404852) Cronobacter sakazakii ATCC BAA-894 5550866 YP_001438539.1 CDS clpS NC_009778.1 2404881 2405201 R involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS complement(2404881..2405201) Cronobacter sakazakii ATCC BAA-894 5550804 YP_001438540.1 CDS ESA_02458 NC_009778.1 2405527 2405757 D COG: COG1278 Cold shock proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 2405527..2405757 Cronobacter sakazakii ATCC BAA-894 5550846 YP_001438541.1 CDS ESA_02459 NC_009778.1 2405822 2407765 R with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease protein complement(2405822..2407765) Cronobacter sakazakii ATCC BAA-894 5550909 YP_001438542.1 CDS ESA_02460 NC_009778.1 2407762 2408874 R confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA complement(2407762..2408874) Cronobacter sakazakii ATCC BAA-894 5550868 YP_001438543.1 CDS ESA_02461 NC_009778.1 2409035 2409988 D COG: COG2990 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 2409035..2409988 Cronobacter sakazakii ATCC BAA-894 5550905 YP_001438544.1 CDS ESA_02462 NC_009778.1 2410093 2411751 R COG: COG3593 Predicted ATP-dependent endonuclease of the OLD family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2410093..2411751) Cronobacter sakazakii ATCC BAA-894 5550920 YP_001438545.1 CDS ESA_02463 NC_009778.1 2412025 2412924 D COG: COG2431 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein 2412025..2412924 Cronobacter sakazakii ATCC BAA-894 5550850 YP_001438546.1 CDS ESA_02464 NC_009778.1 2413134 2414717 D catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 2413134..2414717 Cronobacter sakazakii ATCC BAA-894 5550930 YP_001438547.1 CDS ESA_02465 NC_009778.1 2414761 2415696 D KEGG: eci:UTI89_C0875 3.7e-141 hcr; NADH oxidoreductase; COG: COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Psort location: cytoplasmic, score: 23; HCP oxidoreductase, NADH-dependent 2414761..2415696 Cronobacter sakazakii ATCC BAA-894 5550886 YP_001438548.1 CDS ESA_02466 NC_009778.1 2416045 2417763 D catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 2416045..2417763 Cronobacter sakazakii ATCC BAA-894 5550940 YP_001438549.1 CDS ESA_02467 NC_009778.1 2417843 2418805 D low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 2417843..2418805 Cronobacter sakazakii ATCC BAA-894 5550935 YP_001438550.1 CDS ESA_02468 NC_009778.1 2418935 2419951 D KEGG: eci:UTI89_C0871 1.8e-155 ybjS; hypothetical protein YbjS K00067; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein 2418935..2419951 Cronobacter sakazakii ATCC BAA-894 5550885 YP_001438551.1 CDS ESA_02469 NC_009778.1 2420013 2420843 R KEGG: ecs:ECs0953 8.9e-108 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG3023 Negative regulator of beta-lactamase expression; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2420013..2420843) Cronobacter sakazakii ATCC BAA-894 5550986 YP_001438552.1 CDS ESA_02470 NC_009778.1 2420840 2421163 R COG: COG0393 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2420840..2421163) Cronobacter sakazakii ATCC BAA-894 5550942 YP_001438553.1 CDS ESA_02471 NC_009778.1 2421292 2421819 D induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein 2421292..2421819 Cronobacter sakazakii ATCC BAA-894 5550897 YP_001438554.1 CDS artP NC_009778.1 2422022 2422750 D With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 2422022..2422750 Cronobacter sakazakii ATCC BAA-894 5550939 YP_001438555.1 CDS ESA_02473 NC_009778.1 2422753 2423502 D KEGG: eci:UTI89_C2121 1.0e-28 fliY; cystine-binding periplasmic protein precursor K02030:K02424; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2422753..2423502 Cronobacter sakazakii ATCC BAA-894 5550994 YP_001438556.1 CDS ESA_02474 NC_009778.1 2423511 2424227 D with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 2423511..2424227 Cronobacter sakazakii ATCC BAA-894 5551010 YP_001438557.1 CDS artM NC_009778.1 2424227 2424895 D with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 2424227..2424895 Cronobacter sakazakii ATCC BAA-894 5550995 YP_001438558.1 CDS ESA_02476 NC_009778.1 2424917 2425036 D Psort location: cytoplasmic, score: 23; hypothetical protein 2424917..2425036 Cronobacter sakazakii ATCC BAA-894 5551069 YP_001438559.1 CDS ESA_02477 NC_009778.1 2425246 2425977 D KEGG: eci:UTI89_C2121 4.3e-28 fliY; cystine-binding periplasmic protein precursor K02030:K02424; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2425246..2425977 Cronobacter sakazakii ATCC BAA-894 5551033 YP_001438560.1 CDS rumB NC_009778.1 2426374 2427501 R RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase complement(2426374..2427501) Cronobacter sakazakii ATCC BAA-894 5551087 YP_001438561.1 CDS ESA_02479 NC_009778.1 2427554 2427988 R COG: NOG08677 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2427554..2427988) Cronobacter sakazakii ATCC BAA-894 5550992 YP_001438562.1 CDS ESA_02480 NC_009778.1 2428102 2428947 R KEGG: cya:CYA_1846 4.0e-14 modB; molybdate ABC transporter, permease protein K02018; COG: COG1177 ABC-type spermidine/putrescine transport system, permease component II; Psort location: plasma membrane, score: 23; putrescine transporter subunit: membrane component of ABC superfamily complement(2428102..2428947) Cronobacter sakazakii ATCC BAA-894 5551054 YP_001438563.1 CDS ESA_02481 NC_009778.1 2428944 2429903 R KEGG: hpa:HPAG1_0451 2.1e-09 molybdenum ABC transporter ModB K06022; COG: COG1176 ABC-type spermidine/putrescine transport system, permease component I; Psort location: endoplasmic reticulum, score: 9; putrescine transporter subunit: membrane component of ABC superfamily complement(2428944..2429903) Cronobacter sakazakii ATCC BAA-894 5551064 YP_001438564.1 CDS potG NC_009778.1 2429914 2431170 R part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding subunit complement(2429914..2431170) Cronobacter sakazakii ATCC BAA-894 5550978 YP_001438565.1 CDS ESA_02483 NC_009778.1 2431187 2432368 R COG: COG0687 Spermidine/putrescine-binding periplasmic protein; Psort location: cytoplasmic, score: 23; putrescine transporter subunit: periplasmic-binding component of ABC superfamily complement(2431187..2432368) Cronobacter sakazakii ATCC BAA-894 5551106 YP_001438566.1 CDS ESA_02484 NC_009778.1 2432658 2433029 R COG: NOG08676 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2432658..2433029) Cronobacter sakazakii ATCC BAA-894 5550958 YP_001438567.1 CDS ESA_02485 NC_009778.1 2433218 2434006 R KEGG: mes:Meso_3585 3.2e-16 glutathione synthetase K01920; COG: COG0189 glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Psort location: cytoplasmic, score: 23; hypothetical protein complement(2433218..2434006) Cronobacter sakazakii ATCC BAA-894 5551071 YP_001438568.1 CDS ESA_02486 NC_009778.1 2434198 2434971 R NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A complement(2434198..2434971) Cronobacter sakazakii ATCC BAA-894 5551060 YP_001438569.1 CDS ESA_02487 NC_009778.1 2435050 2435367 R COG: NOG09759 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2435050..2435367) Cronobacter sakazakii ATCC BAA-894 5551133 YP_001438570.1 CDS ESA_02488 NC_009778.1 2435720 2437402 D COG: COG2985 Predicted permease; Psort location: plasma membrane, score: 23; hypothetical protein 2435720..2437402 Cronobacter sakazakii ATCC BAA-894 5551051 YP_001438571.1 CDS ESA_02490 NC_009778.1 2437703 2437921 R Psort location: golgi, score: 9; hypothetical protein complement(2437703..2437921) Cronobacter sakazakii ATCC BAA-894 5551155 YP_001438572.1 CDS ESA_02491 NC_009778.1 2438052 2438780 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2438052..2438780 Cronobacter sakazakii ATCC BAA-894 5551131 YP_001438573.1 CDS ESA_02492 NC_009778.1 2438897 2439442 R COG: COG3226 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2438897..2439442) Cronobacter sakazakii ATCC BAA-894 5551223 YP_001438574.1 CDS ESA_02493 NC_009778.1 2439489 2440772 D KEGG: eci:UTI89_C5041 4.7e-05 yjiJ; hypothetical protein YjiJ K00403; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 2439489..2440772 Cronobacter sakazakii ATCC BAA-894 5551165 YP_001438575.1 CDS ESA_02494 NC_009778.1 2440765 2442216 R COG: COG1344 Flagellin and related hook-associated proteins; Psort location: nuclear, score: 23; hypothetical protein complement(2440765..2442216) Cronobacter sakazakii ATCC BAA-894 5551202 YP_001438576.1 CDS ESA_02495 NC_009778.1 2442397 2443209 D KEGG: sbo:SBO_0712 3.6e-72 hypothetical protein K07757; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein 2442397..2443209 Cronobacter sakazakii ATCC BAA-894 5551185 YP_001438577.1 CDS ESA_02496 NC_009778.1 2443243 2444475 R KEGG: shn:Shewana3_1692 1.2e-05 Xaa-His dipeptidase K01270; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(2443243..2444475) Cronobacter sakazakii ATCC BAA-894 5551272 YP_001438578.1 CDS ESA_02497 NC_009778.1 2444576 2445382 D COG: COG3907 PAP2 (acid phosphatase) superfamily protein; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 2444576..2445382 Cronobacter sakazakii ATCC BAA-894 5551328 YP_001438579.1 CDS ESA_02498 NC_009778.1 2445379 2445972 D KEGG: btk:BT9727_2194 3.1e-11 probable phosphatase, PAP2 superfamily; possible bacitracin transport permease K01112; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: endoplasmic reticulum, score: 9; undecaprenyl pyrophosphate phosphatase 2445379..2445972 Cronobacter sakazakii ATCC BAA-894 5551313 YP_001438580.1 CDS ESA_02499 NC_009778.1 2446052 2446816 D COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: cytoplasmic, score: 23; DNA-binding transcriptional repressor DeoR 2446052..2446816 Cronobacter sakazakii ATCC BAA-894 5551153 YP_001438581.1 CDS ESA_02500 NC_009778.1 2446844 2448076 R penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C complement(2446844..2448076) Cronobacter sakazakii ATCC BAA-894 5550878 YP_001438582.1 CDS ESA_02501 NC_009778.1 2448302 2448928 D KEGG: eci:UTI89_C0841 8.2e-82 yliJ; hypothetical GST-like protein YliJ K00799; COG: COG0625 glutathione S-transferase; Psort location: cytoplasmic, score: 23; hypothetical protein 2448302..2448928 Cronobacter sakazakii ATCC BAA-894 5551265 YP_001438583.1 CDS ESA_02502 NC_009778.1 2448929 2450191 R KEGG: azo:azo1253 1.3e-76 conserved hypothetical protein K00117; COG: COG2133 Glucose/sorbosone dehydrogenases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2448929..2450191) Cronobacter sakazakii ATCC BAA-894 5551322 YP_001438584.1 CDS rimO NC_009778.1 2450212 2451537 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 2450212..2451537 Cronobacter sakazakii ATCC BAA-894 5551364 YP_001438585.1 CDS ESA_02504 NC_009778.1 2451959 2452870 R KEGG: rha:RHA1_ro09047 7.9e-05 ABC peptide transporter, permease component K02033; COG: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2451959..2452870) Cronobacter sakazakii ATCC BAA-894 5551356 YP_001438586.1 CDS ESA_02505 NC_009778.1 2452873 2453793 R KEGG: rha:RHA1_ro09047 1.7e-42 ABC peptide transporter, permease component K02033; COG: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2452873..2453793) Cronobacter sakazakii ATCC BAA-894 5551402 YP_001438587.1 CDS ESA_02506 NC_009778.1 2454128 2455666 R KEGG: shn:Shewana3_2650 3.9e-30 acetate kinase K00925; COG: COG0747 ABC-type dipeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2454128..2455666) Cronobacter sakazakii ATCC BAA-894 5551407 YP_001438588.1 CDS ESA_02507 NC_009778.1 2455696 2457570 R with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein complement(2455696..2457570) Cronobacter sakazakii ATCC BAA-894 5551446 YP_001438589.1 CDS ESA_02508 NC_009778.1 2457563 2457769 R Psort location: nuclear, score: 23; hypothetical protein complement(2457563..2457769) Cronobacter sakazakii ATCC BAA-894 5552190 YP_001438590.1 CDS ESA_02509 NC_009778.1 2457806 2459035 D is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 2457806..2459035 Cronobacter sakazakii ATCC BAA-894 5552306 YP_001438591.1 CDS ESA_02510 NC_009778.1 2459037 2459795 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 2459037..2459795 Cronobacter sakazakii ATCC BAA-894 5551484 YP_001438592.1 CDS ESA_02511 NC_009778.1 2459792 2460874 R COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2459792..2460874) Cronobacter sakazakii ATCC BAA-894 5551483 YP_001438593.1 CDS ESA_02512 NC_009778.1 2461168 2462478 D KEGG: dre:30298 0.0020 jak2b; Janus kinase 2b K04447; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2461168..2462478 Cronobacter sakazakii ATCC BAA-894 5551499 YP_001438594.1 CDS ESA_02513 NC_009778.1 2462483 2464852 D KEGG: ssn:SSO_0800 0. putative glucosidase K01187; COG: COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein 2462483..2464852 Cronobacter sakazakii ATCC BAA-894 5551535 YP_001438595.1 CDS ESA_02514 NC_009778.1 2464876 2465031 R Psort location: nuclear, score: 23; hypothetical protein complement(2464876..2465031) Cronobacter sakazakii ATCC BAA-894 5551571 YP_001438596.1 CDS ESA_02515 NC_009778.1 2465440 2465583 D Psort location: cytoplasmic, score: 23; hypothetical protein 2465440..2465583 Cronobacter sakazakii ATCC BAA-894 5551488 YP_001438597.1 CDS ESA_02516 NC_009778.1 2465658 2467742 D KEGG: eci:UTI89_C4946 3.1e-66 putative member of ShlA/HecA/FhaA exoprotein family; COG: COG3210 Large exoproteins involved in heme utilization or adhesion; Psort location: nuclear, score: 23; hypothetical protein 2465658..2467742 Cronobacter sakazakii ATCC BAA-894 5551527 YP_001438598.1 CDS ESA_02517 NC_009778.1 2467823 2469391 R KEGG: eci:UTI89_C0824 8.7e-268 ybiT; hypothetical ABC transporter ATP-binding protein YbiT K01957; COG: COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2467823..2469391) Cronobacter sakazakii ATCC BAA-894 5551593 YP_001438599.1 CDS ESA_02518 NC_009778.1 2469635 2470555 D KEGG: eci:UTI89_C2228 3.3e-101 erfK; hypothetical protein K00257; COG: COG1376 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2469635..2470555 Cronobacter sakazakii ATCC BAA-894 5551592 YP_001438600.1 CDS ESA_02519 NC_009778.1 2470628 2472169 R KEGG: hdu:HD1819 0.0039 dnaX; DNA polymerase III subunits gamma and tau K02343; COG: COG1538 Outer membrane protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2470628..2472169) Cronobacter sakazakii ATCC BAA-894 5552253 YP_001438601.1 CDS ESA_02520 NC_009778.1 2472171 2473742 R KEGG: sgl:SG1466 1.9e-10 dethiobiotinsynthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(2472171..2473742) Cronobacter sakazakii ATCC BAA-894 5549438 YP_001438602.1 CDS ESA_02521 NC_009778.1 2473739 2474896 R KEGG: lpp:lpp3057 0.0033 atpF; F-type H+-transporting ATPase b chain K02109; COG: COG1566 Multidrug resistance efflux pump; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2473739..2474896) Cronobacter sakazakii ATCC BAA-894 5550310 YP_001438603.1 CDS ESA_02522 NC_009778.1 2474997 2476115 R COG: COG0471 Di- and tricarboxylate transporters; Psort location: plasma membrane, score: 23; hypothetical protein complement(2474997..2476115) Cronobacter sakazakii ATCC BAA-894 5551588 YP_001438604.1 CDS ESA_02523 NC_009778.1 2476118 2476585 R Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR complement(2476118..2476585) Cronobacter sakazakii ATCC BAA-894 5551596 YP_001438605.1 CDS ESA_02524 NC_009778.1 2476778 2476921 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2476778..2476921) Cronobacter sakazakii ATCC BAA-894 5549418 YP_001438606.1 CDS ESA_02525 NC_009778.1 2477196 2478779 D KEGG: eci:UTI89_C0819 1.5e-222 ybiP; hypothetical protein YbiP K00924; COG: COG2194 Predicted membrane-associated, metal-dependent hydrolase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2477196..2478779 Cronobacter sakazakii ATCC BAA-894 5549434 YP_001438607.1 CDS ompX NC_009778.1 2478859 2479371 R OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X complement(2478859..2479371) Cronobacter sakazakii ATCC BAA-894 5551600 YP_001438608.1 CDS ESA_02527 NC_009778.1 2479721 2480608 D KEGG: pae:PA1977 4.6e-09 sensor protein GLPS; COG: COG5006 Predicted permease, DMT superfamily; Psort location: plasma membrane, score: 23; threonine and homoserine efflux system 2479721..2480608 Cronobacter sakazakii ATCC BAA-894 5551623 YP_001438609.1 CDS ESA_02528 NC_009778.1 2480924 2481427 D binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 2480924..2481427 Cronobacter sakazakii ATCC BAA-894 5551648 YP_001438610.1 CDS glnH NC_009778.1 2481758 2482546 D similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 2481758..2482546 Cronobacter sakazakii ATCC BAA-894 5549428 YP_001438611.1 CDS glnP NC_009778.1 2482630 2483289 D similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease protein 2482630..2483289 Cronobacter sakazakii ATCC BAA-894 5551650 YP_001438612.1 CDS glnQ NC_009778.1 2483286 2484008 D similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 2483286..2484008 Cronobacter sakazakii ATCC BAA-894 5551590 YP_001438613.1 CDS ESA_02532 NC_009778.1 2484445 2486730 D COG: COG0668 Small-conductance mechanosensitive channel; Psort location: plasma membrane, score: 23; hypothetical protein 2484445..2486730 Cronobacter sakazakii ATCC BAA-894 5552228 YP_001438614.1 CDS ESA_02533 NC_009778.1 2486731 2487660 R KEGG: vfi:VFA1153 4.0e-80 methyltransferase; COG: COG3129 Predicted SAM-dependent methyltransferase; Psort location: cytoplasmic, score: 23; putative SAM-dependent methyltransferase complement(2486731..2487660) Cronobacter sakazakii ATCC BAA-894 5551598 YP_001438615.1 CDS ESA_02534 NC_009778.1 2487772 2488389 D KEGG: bmf:BAB1_1090 1.8e-38 nitrilotriacetate monooxygenase component B K00492; COG: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; Psort location: cytoplasmic, score: 23; hypothetical protein 2487772..2488389 Cronobacter sakazakii ATCC BAA-894 5551675 YP_001438616.1 CDS ESA_02535 NC_009778.1 2488398 2488748 D COG: COG1734 DnaK suppressor protein; Psort location: nuclear, score: 23; hypothetical protein 2488398..2488748 Cronobacter sakazakii ATCC BAA-894 5551691 YP_001438617.1 CDS ESA_02536 NC_009778.1 2489008 2489268 D COG: NOG13870 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2489008..2489268 Cronobacter sakazakii ATCC BAA-894 5551666 YP_001438618.1 CDS ESA_02537 NC_009778.1 2489357 2490355 R KEGG: rso:RSc0378 6.0e-54 trpD3, RS03346; putative anthranilate phosphoribosyltransferase protein K00766; COG: COG0547 Anthranilate phosphoribosyltransferase; Psort location: cytoplasmic, score: 23; glycosyl transferase family protein complement(2489357..2490355) Cronobacter sakazakii ATCC BAA-894 5552454 YP_001438619.1 CDS ESA_02538 NC_009778.1 2490652 2491191 D COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2490652..2491191 Cronobacter sakazakii ATCC BAA-894 5551455 YP_001438620.1 CDS ESA_02539 NC_009778.1 2491258 2491929 D COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2491258..2491929 Cronobacter sakazakii ATCC BAA-894 5551540 YP_001438621.1 CDS ESA_02540 NC_009778.1 2492061 2494523 D COG: COG3188 P pilus assembly protein, porin PapC; Psort location: nuclear, score: 23; hypothetical protein 2492061..2494523 Cronobacter sakazakii ATCC BAA-894 5551739 YP_001438622.1 CDS ESA_02541 NC_009778.1 2494514 2495521 D KEGG: chu:CHU_1335 0.0090 CHU large protein; endoglucanase-related protein, glucosyl hydrolase family 9 protein K01238; COG: NOG23921 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 2494514..2495521 Cronobacter sakazakii ATCC BAA-894 5551713 YP_001438623.1 CDS ESA_02542 NC_009778.1 2495532 2496041 D COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2495532..2496041 Cronobacter sakazakii ATCC BAA-894 5551764 YP_001438624.1 CDS dinG NC_009778.1 2496032 2498212 R helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG complement(2496032..2498212) Cronobacter sakazakii ATCC BAA-894 5551737 YP_001438625.1 CDS ESA_02544 NC_009778.1 2498505 2499350 D COG: COG3711 Transcriptional antiterminator; Psort location: cytoplasmic, score: 23; hypothetical protein 2498505..2499350 Cronobacter sakazakii ATCC BAA-894 5551765 YP_001438626.1 CDS ESA_02545 NC_009778.1 2499458 2501314 D KEGG: bsu:BG10934 6.0e-157 bglP, sytA, n17C; PTS beta-glucoside-specific enzyme IIBCA component K02755:K02756:K02757; COG: COG2190 Phosphotransferase system IIA components; Psort location: plasma membrane, score: 23; hypothetical protein 2499458..2501314 Cronobacter sakazakii ATCC BAA-894 5551803 YP_001438627.1 CDS ESA_02546 NC_009778.1 2501326 2502798 D KEGG: lin:lin0288 1.6e-156 beta-glucosidase K01188; COG: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Psort location: cytoplasmic, score: 23; hypothetical protein 2501326..2502798 Cronobacter sakazakii ATCC BAA-894 5552365 YP_001438628.1 CDS ESA_02547 NC_009778.1 2502808 2504199 D KEGG: bsu:BG10935 1.8e-148 bglH, n17D; beta-glucosidase K01188; COG: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Psort location: cytoplasmic, score: 23; hypothetical protein 2502808..2504199 Cronobacter sakazakii ATCC BAA-894 5551848 YP_001438629.1 CDS ESA_02548 NC_009778.1 2504616 2506040 R this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE complement(2504616..2506040) Cronobacter sakazakii ATCC BAA-894 5551825 YP_001438630.1 CDS ESA_02549 NC_009778.1 2506266 2506964 D COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; putative DNA-binding transcriptional regulator 2506266..2506964 Cronobacter sakazakii ATCC BAA-894 5551813 YP_001438631.1 CDS ESA_02550 NC_009778.1 2506957 2507958 D COG: COG0845 Membrane-fusion protein; Psort location: mitochondrial, score: 23; hypothetical protein 2506957..2507958 Cronobacter sakazakii ATCC BAA-894 5551841 YP_001438632.1 CDS ESA_02551 NC_009778.1 2507945 2509675 D KEGG: rru:Rru_A1792 1.1e-166 ABC transporter component K01990; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 2507945..2509675 Cronobacter sakazakii ATCC BAA-894 5551920 YP_001438633.1 CDS ESA_02552 NC_009778.1 2509672 2510793 D KEGG: fal:FRAAL1796 1.8e-12 putative ABC transporter ATP-binding subunit; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2509672..2510793 Cronobacter sakazakii ATCC BAA-894 5551788 YP_001438634.1 CDS ESA_02553 NC_009778.1 2510803 2511909 D KEGG: fal:FRAAL1796 1.1e-11 putative ABC transporter ATP-binding subunit; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2510803..2511909 Cronobacter sakazakii ATCC BAA-894 5551908 YP_001438635.1 CDS ESA_02554 NC_009778.1 2511871 2512287 R COG: NOG09757 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2511871..2512287) Cronobacter sakazakii ATCC BAA-894 5551755 YP_001438636.1 CDS ESA_02555 NC_009778.1 2512423 2513184 D KEGG: eci:UTI89_C0791 1.2e-121 ybhP; putative DNase; COG: COG3568 Metal-dependent hydrolase; Psort location: mitochondrial, score: 23; hypothetical protein 2512423..2513184 Cronobacter sakazakii ATCC BAA-894 5551923 YP_001438637.1 CDS ESA_02556 NC_009778.1 2513181 2514422 D KEGG: spt:SPA1941 9.1e-186 ybhO; putative phospholipase K06132; COG: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; Psort location: cytoplasmic, score: 23; cardiolipin synthase 2 2513181..2514422 Cronobacter sakazakii ATCC BAA-894 5551871 YP_001438638.1 CDS ESA_02557 NC_009778.1 2514422 2515450 D COG: COG0392 Predicted integral membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2514422..2515450 Cronobacter sakazakii ATCC BAA-894 5551849 YP_001438639.1 CDS ESA_02558 NC_009778.1 2515668 2516375 R COG: COG0670 Integral membrane protein, interacts with FtsH; Psort location: plasma membrane, score: 23; hypothetical protein complement(2515668..2516375) Cronobacter sakazakii ATCC BAA-894 5551946 YP_001438640.1 CDS moaE NC_009778.1 2516470 2516922 R catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE complement(2516470..2516922) Cronobacter sakazakii ATCC BAA-894 5551956 YP_001438641.1 CDS ESA_02560 NC_009778.1 2516924 2517175 R COG: COG1977 Molybdopterin converting factor, small subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2516924..2517175) Cronobacter sakazakii ATCC BAA-894 5551962 YP_001438642.1 CDS ESA_02561 NC_009778.1 2517162 2517647 R COG: COG0315 Molybdenum cofactor biosynthesis enzyme; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2517162..2517647) Cronobacter sakazakii ATCC BAA-894 5552096 YP_001438643.1 CDS ESA_02562 NC_009778.1 2517651 2518163 R KEGG: mtu:Rv0984 1.9e-11 moaB2; possible pterin-4-alpha-carbinolamine dehydratase MoaB2 (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin-4-A-carbinolamine dehydratase) (phenylalanine hydroxylase-stimulating protein) (PHS) (pterin carbinolamine dehydratase) (PCD); COG: COG0521 Molybdopterin biosynthesis enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2517651..2518163) Cronobacter sakazakii ATCC BAA-894 5552058 YP_001438644.1 CDS moaA NC_009778.1 2518185 2519174 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(2518185..2519174) Cronobacter sakazakii ATCC BAA-894 5552134 YP_001438645.1 CDS ESA_02564 NC_009778.1 2519368 2519502 D Psort location: mitochondrial, score: 23; hypothetical protein 2519368..2519502 Cronobacter sakazakii ATCC BAA-894 5552099 YP_001438646.1 CDS ESA_02565 NC_009778.1 2519519 2520427 D KEGG: nph:NP2028A 1.4e-05 hypothetical protein K00924; COG: COG0391 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 2519519..2520427 Cronobacter sakazakii ATCC BAA-894 5552216 YP_001438647.1 CDS ESA_02566 NC_009778.1 2520652 2522727 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(2520652..2522727) Cronobacter sakazakii ATCC BAA-894 5552141 YP_001438648.1 CDS ESA_02567 NC_009778.1 2523154 2523411 R Psort location: nuclear, score: 23; hypothetical protein complement(2523154..2523411) Cronobacter sakazakii ATCC BAA-894 5552098 YP_001438649.1 CDS ESA_02568 NC_009778.1 2523564 2524271 D KEGG: reh:H16_A1079 7.5e-40 ABC-type transporter, ATPase component: HAAT family; COG: COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 2523564..2524271 Cronobacter sakazakii ATCC BAA-894 5549668 YP_001438650.1 CDS bioD NC_009778.1 2524268 2524951 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(2524268..2524951) Cronobacter sakazakii ATCC BAA-894 5552261 YP_001438651.1 CDS ESA_02570 NC_009778.1 2524944 2525702 R putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC complement(2524944..2525702) Cronobacter sakazakii ATCC BAA-894 5549666 YP_001438652.1 CDS ESA_02571 NC_009778.1 2525686 2526837 R KEGG: sbo:SBO_0663 1.0e-129 bioF; 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2525686..2526837) Cronobacter sakazakii ATCC BAA-894 5549601 YP_001438653.1 CDS ESA_02572 NC_009778.1 2526834 2527874 R KEGG: ecc:c0855 1.8e-173 bioB; biotin synthase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2526834..2527874) Cronobacter sakazakii ATCC BAA-894 5552465 YP_001438654.1 CDS ESA_02573 NC_009778.1 2527956 2529248 D catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 2527956..2529248 Cronobacter sakazakii ATCC BAA-894 5552250 YP_001438655.1 CDS ESA_02574 NC_009778.1 2529316 2529996 D KEGG: psp:PSPPH_3239 8.8e-85 ThiJ/PfpI family protein K01423; COG: COG0693 Putative intracellular protease/amidase; Psort location: cytoplasmic, score: 23; hypothetical protein 2529316..2529996 Cronobacter sakazakii ATCC BAA-894 5549482 YP_001438656.1 CDS ESA_02575 NC_009778.1 2530010 2530486 D YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein 2530010..2530486 Cronobacter sakazakii ATCC BAA-894 5552274 YP_001438657.1 CDS ESA_02576 NC_009778.1 2530728 2531906 D outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase 2530728..2531906 Cronobacter sakazakii ATCC BAA-894 5549472 YP_001438658.1 CDS ESA_02577 NC_009778.1 2532093 2533094 R catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase complement(2532093..2533094) Cronobacter sakazakii ATCC BAA-894 5549467 YP_001438659.1 CDS ESA_02578 NC_009778.1 2533246 2534064 D YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 2533246..2534064 Cronobacter sakazakii ATCC BAA-894 5549667 YP_001438660.1 CDS modC NC_009778.1 2534061 2535119 R Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein complement(2534061..2535119) Cronobacter sakazakii ATCC BAA-894 5549521 YP_001438661.1 CDS modB NC_009778.1 2535119 2535811 R part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease protein complement(2535119..2535811) Cronobacter sakazakii ATCC BAA-894 5549640 YP_001438662.1 CDS modA NC_009778.1 2535808 2536584 R with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein complement(2535808..2536584) Cronobacter sakazakii ATCC BAA-894 5551015 YP_001438663.1 CDS ESA_02582 NC_009778.1 2536728 2536976 R COG: NOG17580 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2536728..2536976) Cronobacter sakazakii ATCC BAA-894 5551414 YP_001438664.1 CDS ESA_02583 NC_009778.1 2537006 2537797 D represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 2537006..2537797 Cronobacter sakazakii ATCC BAA-894 5549673 YP_001438665.1 CDS ESA_02585 NC_009778.1 2537794 2537949 R Psort location: nuclear, score: 23; hypothetical protein complement(2537794..2537949) Cronobacter sakazakii ATCC BAA-894 5549551 YP_001438666.1 CDS ESA_02584 NC_009778.1 2537857 2539341 D contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF 2537857..2539341 Cronobacter sakazakii ATCC BAA-894 5549694 YP_001438667.1 CDS ESA_02586 NC_009778.1 2539524 2540582 D KEGG: stm:STM0776 2.3e-171 galE; UDP-galactose 4-epimerase K01784; COG: COG1087 UDP-glucose 4-epimerase; Psort location: cytoplasmic, score: 23; UDP-galactose-4-epimerase 2539524..2540582 Cronobacter sakazakii ATCC BAA-894 5551885 YP_001438668.1 CDS ESA_02587 NC_009778.1 2540593 2541639 D catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 2540593..2541639 Cronobacter sakazakii ATCC BAA-894 5549610 YP_001438669.1 CDS ESA_02588 NC_009778.1 2541642 2542790 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 2541642..2542790 Cronobacter sakazakii ATCC BAA-894 5549457 YP_001438670.1 CDS galM NC_009778.1 2542784 2543824 D catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 2542784..2543824 Cronobacter sakazakii ATCC BAA-894 5549498 YP_001438671.1 CDS gpmA NC_009778.1 2544032 2544784 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 2544032..2544784 Cronobacter sakazakii ATCC BAA-894 5549455 YP_001438672.1 CDS ESA_02591 NC_009778.1 2544987 2546039 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2544987..2546039) Cronobacter sakazakii ATCC BAA-894 5549687 YP_001438673.1 CDS ESA_02592 NC_009778.1 2546253 2546756 D KEGG: cal:orf19.4072 2.0e-08 HYR10; similar to cell surface flocculin K01186; COG: NOG09755 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 2546253..2546756 Cronobacter sakazakii ATCC BAA-894 5550851 YP_001438674.1 CDS ESA_02593 NC_009778.1 2546270 2546779 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2546270..2546779) Cronobacter sakazakii ATCC BAA-894 5550859 YP_001438675.1 CDS ESA_02594 NC_009778.1 2546884 2547846 D involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 2546884..2547846 Cronobacter sakazakii ATCC BAA-894 5550854 YP_001438676.1 CDS ESA_02595 NC_009778.1 2547843 2548562 R COG: COG3201 Nicotinamide mononucleotide transporter; Psort location: plasma membrane, score: 23; hypothetical protein complement(2547843..2548562) Cronobacter sakazakii ATCC BAA-894 5549018 YP_001438677.1 CDS ESA_02596 NC_009778.1 2548584 2549654 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(2548584..2549654) Cronobacter sakazakii ATCC BAA-894 5552363 YP_001438678.1 CDS ESA_02603 NC_009778.1 2550896 2551693 R periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF complement(2550896..2551693) Cronobacter sakazakii ATCC BAA-894 5550826 YP_001438679.1 CDS ESA_02602 NC_009778.1 2551670 2552320 D Psort location: cytoplasmic, score: 23; hypothetical protein 2551670..2552320 Cronobacter sakazakii ATCC BAA-894 5550792 YP_001438680.1 CDS ESA_02604 NC_009778.1 2551703 2552221 R KEGG: bxe:Bxe_A4171 1.5e-07 putative cytochrome c oxidase K00403; COG: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Psort location: nuclear, score: 23; peptidoglycan-associated outer membrane lipoprotein complement(2551703..2552221) Cronobacter sakazakii ATCC BAA-894 5550806 YP_001438681.1 CDS tolB NC_009778.1 2552256 2553551 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(2552256..2553551) Cronobacter sakazakii ATCC BAA-894 5550773 YP_001438682.1 CDS tolA NC_009778.1 2553672 2554910 R inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA complement(2553672..2554910) Cronobacter sakazakii ATCC BAA-894 5550800 YP_001438683.1 CDS ESA_02608 NC_009778.1 2554950 2555378 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR complement(2554950..2555378) Cronobacter sakazakii ATCC BAA-894 5550772 YP_001438684.1 CDS ESA_02607 NC_009778.1 2555109 2556005 D Psort location: cytoplasmic, score: 23; hypothetical protein 2555109..2556005 Cronobacter sakazakii ATCC BAA-894 5550784 YP_001438685.1 CDS ESA_02609 NC_009778.1 2555382 2556077 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ complement(2555382..2556077) Cronobacter sakazakii ATCC BAA-894 5550763 YP_001438686.1 CDS ESA_02610 NC_009778.1 2556083 2556487 R catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC complement(2556083..2556487) Cronobacter sakazakii ATCC BAA-894 5550783 YP_001438687.1 CDS ESA_02611 NC_009778.1 2556621 2556914 R COG: COG3790 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2556621..2556914) Cronobacter sakazakii ATCC BAA-894 5550764 YP_001438688.1 CDS ESA_02612 NC_009778.1 2556914 2557027 R COG: COG4890 Predicted outer membrane lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2556914..2557027) Cronobacter sakazakii ATCC BAA-894 5550668 YP_001438689.1 CDS ESA_02613 NC_009778.1 2557041 2558180 R KEGG: spt:SPA2002 1.0e-184 cydB; cytochrome d ubiquinol oxidase subunit II K00426; COG: COG1294 Cytochrome bd-type quinol oxidase, subunit 2; Psort location: plasma membrane, score: 23; hypothetical protein complement(2557041..2558180) Cronobacter sakazakii ATCC BAA-894 5550744 YP_001438690.1 CDS ESA_02614 NC_009778.1 2558196 2559764 R KEGG: ece:Z0900 8.5e-261 cydA; cytochrome d terminal oxidase, polypeptide subunit I K00425; COG: COG1271 Cytochrome bd-type quinol oxidase, subunit 1; Psort location: plasma membrane, score: 23; hypothetical protein complement(2558196..2559764) Cronobacter sakazakii ATCC BAA-894 5550761 YP_001438691.1 CDS ESA_02615 NC_009778.1 2560362 2560493 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2560362..2560493) Cronobacter sakazakii ATCC BAA-894 5550757 YP_001438692.1 CDS ESA_02616 NC_009778.1 2560448 2563054 R KEGG: lmf:LMOf2365_0421 4.7e-141 glycosyl hydrolase, family 38 K01191; COG: COG0383 Alpha-mannosidase; Psort location: cytoplasmic, score: 23; alpha-mannosidase complement(2560448..2563054) Cronobacter sakazakii ATCC BAA-894 5550765 YP_001438693.1 CDS ESA_02617 NC_009778.1 2563115 2565043 R involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC complement(2563115..2565043) Cronobacter sakazakii ATCC BAA-894 5550752 YP_001438694.1 CDS ESA_02618 NC_009778.1 2565213 2565929 D regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 2565213..2565929 Cronobacter sakazakii ATCC BAA-894 5550767 YP_001438695.1 CDS ESA_02619 NC_009778.1 2566011 2566880 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(2566011..2566880) Cronobacter sakazakii ATCC BAA-894 5550768 YP_001438696.1 CDS sucC NC_009778.1 2566880 2568046 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(2566880..2568046) Cronobacter sakazakii ATCC BAA-894 5550758 YP_001438697.1 CDS ESA_02621 NC_009778.1 2568157 2569380 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase complement(2568157..2569380) Cronobacter sakazakii ATCC BAA-894 5550741 YP_001438698.1 CDS sucA NC_009778.1 2569395 2572202 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(2569395..2572202) Cronobacter sakazakii ATCC BAA-894 5550703 YP_001438699.1 CDS sdhB NC_009778.1 2572645 2573361 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(2572645..2573361) Cronobacter sakazakii ATCC BAA-894 5550739 YP_001438700.1 CDS sdhA NC_009778.1 2573377 2575143 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(2573377..2575143) Cronobacter sakazakii ATCC BAA-894 5550746 YP_001438701.1 CDS sdhD NC_009778.1 2575144 2575491 R KEGG: ssn:SSO_0673 1.3e-49 sdhD; succinate dehydrogenase, hydrophobic subunit K00242; COG: COG2142 Succinate dehydrogenase, hydrophobic anchor subunit; Psort location: endoplasmic reticulum, score: 9; succinate dehydrogenase cytochrome b556 small membrane subunit complement(2575144..2575491) Cronobacter sakazakii ATCC BAA-894 5551897 YP_001438702.1 CDS ESA_02626 NC_009778.1 2575485 2575874 R KEGG: spt:SPA2011 5.4e-53 sdhC; succinate dehydrogenase cytochrome b-556 subunit K00241; COG: COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2575485..2575874) Cronobacter sakazakii ATCC BAA-894 5550711 YP_001438703.1 CDS gltA NC_009778.1 2576528 2577814 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 2576528..2577814 Cronobacter sakazakii ATCC BAA-894 5552168 YP_001438704.1 CDS ESA_02628 NC_009778.1 2577963 2578754 R 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII complement(2577963..2578754) Cronobacter sakazakii ATCC BAA-894 5550707 YP_001438705.1 CDS ESA_02629 NC_009778.1 2578860 2579855 R COG: NOG06103 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2578860..2579855) Cronobacter sakazakii ATCC BAA-894 5550733 YP_001438706.1 CDS ESA_02630 NC_009778.1 2579875 2580861 R COG: COG3817 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(2579875..2580861) Cronobacter sakazakii ATCC BAA-894 5550636 YP_001438707.1 CDS ESA_02631 NC_009778.1 2580858 2581580 R COG: COG3819 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2580858..2581580) Cronobacter sakazakii ATCC BAA-894 5550726 YP_001438708.1 CDS ESA_02632 NC_009778.1 2581608 2581742 D Psort location: nuclear, score: 23; hypothetical protein 2581608..2581742 Cronobacter sakazakii ATCC BAA-894 5550682 YP_001438709.1 CDS ESA_02633 NC_009778.1 2581825 2582373 D COG: COG5631 Predicted transcription regulator, contains HTH domain (MarR family); Psort location: cytoplasmic, score: 23; hypothetical protein 2581825..2582373 Cronobacter sakazakii ATCC BAA-894 5550675 YP_001438710.1 CDS ESA_02634 NC_009778.1 2582375 2583112 R COG: COG1540 Uncharacterized proteins, homologs of lactam utilization protein B; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2582375..2583112) Cronobacter sakazakii ATCC BAA-894 5550647 YP_001438711.1 CDS ESA_02635 NC_009778.1 2583099 2584031 R KEGG: eci:UTI89_C0710 5.3e-126 ybgK; hypothetical protein K01941; COG: COG1984 Allophanate hydrolase subunit 2; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2583099..2584031) Cronobacter sakazakii ATCC BAA-894 5552326 YP_001438712.1 CDS ESA_02636 NC_009778.1 2584025 2584642 R KEGG: eci:UTI89_C0709 3.0e-84 ybgJ; hypothetical protein YbgJ K01457; COG: COG2049 Allophanate hydrolase subunit 1; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2584025..2584642) Cronobacter sakazakii ATCC BAA-894 5550652 YP_001438713.1 CDS ESA_02637 NC_009778.1 2584702 2585478 R COG: COG0327 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; putative hydrolase-oxidase complement(2584702..2585478) Cronobacter sakazakii ATCC BAA-894 5552009 YP_001438714.1 CDS ESA_02638 NC_009778.1 2585456 2586877 R UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase complement(2585456..2586877) Cronobacter sakazakii ATCC BAA-894 5550644 YP_001438715.1 CDS ESA_02639 NC_009778.1 2586890 2587843 R KEGG: ctc:CTC02272 9.7e-08 purine nucleoside phosphorylase K00755; COG: COG3272 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2586890..2587843) Cronobacter sakazakii ATCC BAA-894 5550665 YP_001438716.1 CDS ESA_02640 NC_009778.1 2587993 2588223 R COG: NOG13868 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2587993..2588223) Cronobacter sakazakii ATCC BAA-894 5552357 YP_001438717.1 CDS ESA_02641 NC_009778.1 2588604 2590286 D catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 2588604..2590286 Cronobacter sakazakii ATCC BAA-894 5550646 YP_001438718.1 CDS ESA_02642 NC_009778.1 2590283 2592355 D One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 2590283..2592355 Cronobacter sakazakii ATCC BAA-894 5550661 YP_001438719.1 CDS ESA_02643 NC_009778.1 2592367 2592939 D One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 2592367..2592939 Cronobacter sakazakii ATCC BAA-894 5550666 YP_001438720.1 CDS ESA_02644 NC_009778.1 2592949 2595633 D sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 2592949..2595633 Cronobacter sakazakii ATCC BAA-894 5550620 YP_001438721.1 CDS ESA_02645 NC_009778.1 2595630 2596307 D KEGG: eci:UTI89_C0698 2.2e-97 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: cytoplasmic, score: 23; hypothetical protein 2595630..2596307 Cronobacter sakazakii ATCC BAA-894 5550618 YP_001438722.1 CDS ESA_02646 NC_009778.1 2597002 2599197 D KEGG: ssn:SSO_0644 0. speF; orniTHIne decarboxylase isozyme, inducible K01581; COG: COG1982 Arginine/lysine/orniTHIne decarboxylases; Psort location: cytoplasmic, score: 23; ornithine decarboxylase 2597002..2599197 Cronobacter sakazakii ATCC BAA-894 5550629 YP_001438723.1 CDS potE NC_009778.1 2599194 2600510 D catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 2599194..2600510 Cronobacter sakazakii ATCC BAA-894 5550606 YP_001438724.1 CDS ESA_02648 NC_009778.1 2600586 2602247 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(2600586..2602247) Cronobacter sakazakii ATCC BAA-894 5550643 YP_001438725.1 CDS ESA_02649 NC_009778.1 2602251 2602802 R negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA complement(2602251..2602802) Cronobacter sakazakii ATCC BAA-894 5550614 YP_001438726.1 CDS ESA_02650 NC_009778.1 2602986 2603753 D KEGG: spt:SPA2045 2.8e-104 ybfF; putative esterase/lipase YbfF; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein 2602986..2603753 Cronobacter sakazakii ATCC BAA-894 5550634 YP_001438727.1 CDS ESA_02651 NC_009778.1 2603882 2604163 D COG: NOG13544 non supervised orthologous group; Psort location: nuclear, score: 23; LexA regulated protein 2603882..2604163 Cronobacter sakazakii ATCC BAA-894 5550623 YP_001438728.1 CDS ESA_02652 NC_009778.1 2604325 2604855 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 2604325..2604855 Cronobacter sakazakii ATCC BAA-894 5550541 YP_001438729.1 CDS fur NC_009778.1 2605095 2605598 D negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 2605095..2605598 Cronobacter sakazakii ATCC BAA-894 5550631 YP_001438730.1 CDS ESA_02654 NC_009778.1 2605921 2606532 D COG: NOG06782 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 2605921..2606532 Cronobacter sakazakii ATCC BAA-894 5550561 YP_001438731.1 CDS ESA_02655 NC_009778.1 2606585 2609236 R KEGG: yps:YPTB1123 0. beta-N-acetylhexosaminidase K01207; COG: COG3525 N-acetyl-beta-hexosaminidase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2606585..2609236) Cronobacter sakazakii ATCC BAA-894 5550592 YP_001438732.1 CDS ESA_02656 NC_009778.1 2609293 2610726 R KEGG: psp:PSPPH_3782 9.5e-12 porin D; COG: NOG06287 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2609293..2610726) Cronobacter sakazakii ATCC BAA-894 5552130 YP_001438733.1 CDS ESA_02658 NC_009778.1 2611130 2612797 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(2611130..2612797) Cronobacter sakazakii ATCC BAA-894 5550573 YP_001438734.1 CDS ESA_02657 NC_009778.1 2611202 2612839 D Psort location: cytoplasmic, score: 23; hypothetical protein 2611202..2612839 Cronobacter sakazakii ATCC BAA-894 5550543 YP_001438735.1 CDS ESA_02659 NC_009778.1 2612904 2613320 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2612904..2613320) Cronobacter sakazakii ATCC BAA-894 5550532 YP_001438736.1 CDS ESA_02660 NC_009778.1 2613450 2615432 R KEGG: yps:YPTB1120 8.3e-279 nagE, pstN; PTS system, N-acetylglucosamine-specific IIABC component K02802:K02803:K02804; COG: COG2190 Phosphotransferase system IIA components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2613450..2615432) Cronobacter sakazakii ATCC BAA-894 5550539 YP_001438737.1 CDS nagB NC_009778.1 2615792 2616592 D catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 2615792..2616592 Cronobacter sakazakii ATCC BAA-894 5550558 YP_001438738.1 CDS nagA NC_009778.1 2616614 2617762 D catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 2616614..2617762 Cronobacter sakazakii ATCC BAA-894 5550531 YP_001438739.1 CDS ESA_02663 NC_009778.1 2617771 2618991 D KEGG: eci:UTI89_C0670 1.1e-187 nagC; transcriptional repressor of nag (N-acetylglucosamine) operon K02565; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 2617771..2618991 Cronobacter sakazakii ATCC BAA-894 5552005 YP_001438740.1 CDS ESA_02664 NC_009778.1 2619054 2619806 D KEGG: eci:UTI89_C0669 3.2e-126 nagD; N-acetylglucosamine metabolism K02566; COG: COG0647 Predicted sugar phosphatases of the HAD superfamily; Psort location: cytoplasmic, score: 23; UMP phosphatase 2619054..2619806 Cronobacter sakazakii ATCC BAA-894 5551688 YP_001438741.1 CDS asnB NC_009778.1 2620105 2621769 D functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 2620105..2621769 Cronobacter sakazakii ATCC BAA-894 5550542 YP_001438743.1 CDS ubiF NC_009778.1 2623028 2624209 R catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase complement(2623028..2624209) Cronobacter sakazakii ATCC BAA-894 5550508 YP_001438744.1 CDS ESA_02675 NC_009778.1 2624349 2625773 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2624349..2625773 Cronobacter sakazakii ATCC BAA-894 5552414 YP_001438745.1 CDS ESA_02676 NC_009778.1 2625960 2627039 D KEGG: reh:H16_A0527 2.0e-85 phoH; phosphate starvation-inducible protein PhoH,predicted ATPase; COG: COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; Psort location: cytoplasmic, score: 23; hypothetical protein 2625960..2627039 Cronobacter sakazakii ATCC BAA-894 5548194 YP_001438746.1 CDS ESA_02677 NC_009778.1 2627036 2627503 D KEGG: dps:DP1605 1.5e-08 probable pyridoxal phosphate biosynthetic protein K03474; COG: COG0319 Predicted metal-dependent hydrolase; Psort location: cytoplasmic, score: 23; putative metalloprotease 2627036..2627503 Cronobacter sakazakii ATCC BAA-894 5548292 YP_001438747.1 CDS ESA_02678 NC_009778.1 2627606 2628481 D KEGG: eci:UTI89_C0656 2.5e-142 ybeX; putative transport protein K06189; COG: COG4535 Putative Mg2+ and Co2+ transporter CorC; Psort location: cytoplasmic, score: 23; hypothetical protein 2627606..2628481 Cronobacter sakazakii ATCC BAA-894 5550493 YP_001438748.1 CDS lnt NC_009778.1 2628486 2630027 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2628486..2630027 Cronobacter sakazakii ATCC BAA-894 5550499 YP_001438749.1 CDS ESA_02680 NC_009778.1 2630344 2631294 D KEGG: bur:Bcep18194_A4762 2.1e-21 ABC amino acid transporter, periplasmic ligand binding protein K01713; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: cytoplasmic, score: 23; glutamate and aspartate transporter subunit 2630344..2631294 Cronobacter sakazakii ATCC BAA-894 5550482 YP_001438750.1 CDS ESA_02682 NC_009778.1 2631457 2632197 D KEGG: eca:ECA0855 2.7e-19 ABC transporter permease protein K02028; COG: COG0765 ABC-type amino acid transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2631457..2632197 Cronobacter sakazakii ATCC BAA-894 5550467 YP_001438751.1 CDS ESA_02683 NC_009778.1 2632197 2632871 D KEGG: sma:SAV6546 5.7e-26 putative ABC transporter permease K02028; COG: COG0765 ABC-type amino acid transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2632197..2632871 Cronobacter sakazakii ATCC BAA-894 5550417 YP_001438752.1 CDS ESA_02684 NC_009778.1 2632871 2633596 D KEGG: stt:t2211 6.2e-116 gltL; glutamate/aspartate transport ATP-binding protein GltL K02028; COG: COG1126 ABC-type polar amino acid transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 2632871..2633596 Cronobacter sakazakii ATCC BAA-894 5550478 YP_001438753.1 CDS ESA_02685 NC_009778.1 2633641 2634198 R COG: NOG08739 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(2633641..2634198) Cronobacter sakazakii ATCC BAA-894 5550456 YP_001438754.1 CDS leuS NC_009778.1 2634351 2636933 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 2634351..2636933 Cronobacter sakazakii ATCC BAA-894 5550466 YP_001438755.1 CDS ESA_02687 NC_009778.1 2636987 2637544 D COG: COG2980 Rare lipoprotein B; Psort location: nuclear, score: 23; hypothetical protein 2636987..2637544 Cronobacter sakazakii ATCC BAA-894 5550471 YP_001438756.1 CDS holA NC_009778.1 2637544 2638575 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 2637544..2638575 Cronobacter sakazakii ATCC BAA-894 5550449 YP_001438757.1 CDS nadD NC_009778.1 2638568 2639227 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 2638568..2639227 Cronobacter sakazakii ATCC BAA-894 5550454 YP_001438758.1 CDS ESA_02690 NC_009778.1 2639294 2639848 D KEGG: bba:Bd3846 5.6e-10 probable nicotinate-nucleotide adenylyltransferase K00969; COG: COG0799 Uncharacterized homolog of plant Iojap protein; Psort location: mitochondrial, score: 23; hypothetical protein 2639294..2639848 Cronobacter sakazakii ATCC BAA-894 5550434 YP_001438759.1 CDS ESA_02691 NC_009778.1 2639852 2640319 D SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2639852..2640319 Cronobacter sakazakii ATCC BAA-894 5550422 YP_001438760.1 CDS ESA_02692 NC_009778.1 2640345 2642246 D KEGG: eci:UTI89_C0637 0. mrdA; cell elongation, e phase; peptidoglycan synthetase; penicillin-binding protein 2 K05515; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: cytoplasmic, score: 23; penicillin-binding protein 2 2640345..2642246 Cronobacter sakazakii ATCC BAA-894 5550437 YP_001438761.1 CDS ESA_02693 NC_009778.1 2642248 2643360 D COG: COG0772 Bacterial cell division membrane protein; Psort location: plasma membrane, score: 23; cell wall shape-determining protein 2642248..2643360 Cronobacter sakazakii ATCC BAA-894 5550414 YP_001438762.1 CDS ESA_02694 NC_009778.1 2643371 2644552 D KEGG: ret:RHE_CH01819 5.8e-06 hypothetical protein K01238; COG: COG0797 Lipoproteins; Psort location: extracellular, including cell wall, score: 9; rare lipoprotein A 2643371..2644552 Cronobacter sakazakii ATCC BAA-894 5550423 YP_001438763.1 CDS ESA_02695 NC_009778.1 2644625 2645911 D penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A 2644625..2645911 Cronobacter sakazakii ATCC BAA-894 5550430 YP_001438764.1 CDS ESA_02696 NC_009778.1 2646017 2646280 D COG: COG2921 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 2646017..2646280 Cronobacter sakazakii ATCC BAA-894 5550402 YP_001438765.1 CDS ESA_02698 NC_009778.1 2646287 2646430 R Psort location: nuclear, score: 23; hypothetical protein complement(2646287..2646430) Cronobacter sakazakii ATCC BAA-894 5550388 YP_001438766.1 CDS ESA_02697 NC_009778.1 2646425 2647000 D KEGG: eci:UTI89_C0632 4.2e-78 lipB; lipoate-protein ligase B K03801; COG: COG0321 Lipoate-protein ligase B; Psort location: cytoplasmic, score: 23; hypothetical protein 2646425..2647000 Cronobacter sakazakii ATCC BAA-894 5550404 YP_001438767.1 CDS ESA_02699 NC_009778.1 2647309 2648316 D COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; putative DNA-binding transcriptional regulator 2647309..2648316 Cronobacter sakazakii ATCC BAA-894 5551959 YP_001438768.1 CDS ESA_02700 NC_009778.1 2648507 2649472 D catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2648507..2649472 Cronobacter sakazakii ATCC BAA-894 5550364 YP_001438769.1 CDS tatE NC_009778.1 2649562 2649765 R TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E complement(2649562..2649765) Cronobacter sakazakii ATCC BAA-894 5550406 YP_001438770.1 CDS ESA_02702 NC_009778.1 2649892 2650680 R KEGG: eci:UTI89_C0629 1.6e-94 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2649892..2650680) Cronobacter sakazakii ATCC BAA-894 5550374 YP_001438771.1 CDS ESA_02703 NC_009778.1 2650763 2651146 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 2650763..2651146 Cronobacter sakazakii ATCC BAA-894 5550367 YP_001438772.1 CDS cspE NC_009778.1 2651376 2651585 R member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE complement(2651376..2651585) Cronobacter sakazakii ATCC BAA-894 5550230 YP_001438773.1 CDS pagP NC_009778.1 2651776 2652354 R catalyzes the transfer of palmitate to lipid A; palmitoyl transferase complement(2651776..2652354) Cronobacter sakazakii ATCC BAA-894 5550358 YP_001438774.1 CDS dcuC NC_009778.1 2652815 2654176 D responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 2652815..2654176 Cronobacter sakazakii ATCC BAA-894 5550228 YP_001438775.1 CDS ESA_02707 NC_009778.1 2654284 2655090 D KEGG: ssn:SSO_0563 9.5e-104 rna; RNase I K01169; COG: COG3719 Ribonuclease I; Psort location: extracellular, including cell wall, score: 9; ribonuclease I 2654284..2655090 Cronobacter sakazakii ATCC BAA-894 5550221 YP_001438776.1 CDS ESA_02708 NC_009778.1 2655109 2655393 R COG: NOG18344 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2655109..2655393) Cronobacter sakazakii ATCC BAA-894 5550410 YP_001438777.1 CDS ESA_02709 NC_009778.1 2655476 2657152 R KEGG: bba:Bd2279 8.4e-199 malA; alpha-D-1,4-glucosidase K01187; COG: COG0366 Glycosidases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2655476..2657152) Cronobacter sakazakii ATCC BAA-894 5549916 YP_001438778.1 CDS ESA_02710 NC_009778.1 2657152 2658807 R KEGG: vvy:VVA0760 2.0e-204 glycosidase K01182; COG: COG0366 Glycosidases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2657152..2658807) Cronobacter sakazakii ATCC BAA-894 5550347 YP_001438779.1 CDS ESA_02711 NC_009778.1 2658817 2659932 R KEGG: vvu:VV2_1584 1.2e-101 ABC-type sugar transport system, ATPase component K02023; COG: COG3839 ABC-type sugar transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2658817..2659932) Cronobacter sakazakii ATCC BAA-894 5550365 YP_001438780.1 CDS ESA_02712 NC_009778.1 2659936 2660781 R KEGG: cdi:DIP0495 4.3e-05 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; COG: COG0395 ABC-type sugar transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2659936..2660781) Cronobacter sakazakii ATCC BAA-894 5550433 YP_001438781.1 CDS ESA_02713 NC_009778.1 2660781 2661779 R KEGG: pac:PPA0505 4.5e-08 ABC transporter, putative molybdenum transport system K02017:K02018; COG: COG1175 ABC-type sugar transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2660781..2661779) Cronobacter sakazakii ATCC BAA-894 5550372 YP_001438782.1 CDS ESA_02714 NC_009778.1 2661949 2663214 R COG: COG1653 ABC-type sugar transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2661949..2663214) Cronobacter sakazakii ATCC BAA-894 5550481 YP_001438783.1 CDS ESA_02715 NC_009778.1 2663595 2664989 D KEGG: eci:UTI89_C3106 9.6e-79 ygbN; hypothetical permease YgbN K03299; COG: COG2610 H+/gluconate symporter and related permeases; Psort location: plasma membrane, score: 23; hypothetical protein 2663595..2664989 Cronobacter sakazakii ATCC BAA-894 5550425 YP_001438784.1 CDS ESA_02716 NC_009778.1 2665141 2665551 D Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 2665141..2665551 Cronobacter sakazakii ATCC BAA-894 5550476 YP_001438785.1 CDS ESA_02717 NC_009778.1 2665619 2666860 R KEGG: pst:PSPTO_1875 6.1e-164 fdH; glutathione-dependent formaldehyde dehydrogenase K00121; COG: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2665619..2666860) Cronobacter sakazakii ATCC BAA-894 5550421 YP_001438786.1 CDS ESA_02718 NC_009778.1 2667103 2667531 D COG: COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 2667103..2667531 Cronobacter sakazakii ATCC BAA-894 5550469 YP_001438787.1 CDS ESA_02719 NC_009778.1 2667757 2669322 R KEGG: ecp:ECP_0639 3.4e-257 alkyl hydroperoxide reductase subunit F K03387; COG: COG3634 Alkyl hydroperoxide reductase, large subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2667757..2669322) Cronobacter sakazakii ATCC BAA-894 5550465 YP_001438788.1 CDS ESA_02721 NC_009778.1 2669579 2670142 R with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C complement(2669579..2670142) Cronobacter sakazakii ATCC BAA-894 5550463 YP_001438789.1 CDS ESA_02720 NC_009778.1 2669660 2670175 D Psort location: cytoplasmic, score: 23; hypothetical protein 2669660..2670175 Cronobacter sakazakii ATCC BAA-894 5550435 YP_001438790.1 CDS ESA_02722 NC_009778.1 2670634 2671596 D KEGG: shn:Shewana3_3435 7.7e-08 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 2670634..2671596 Cronobacter sakazakii ATCC BAA-894 5550468 YP_001438791.1 CDS ESA_02723 NC_009778.1 2671591 2672751 R catalyzes the transfer of an amino moiety; putative aminotransferase complement(2671591..2672751) Cronobacter sakazakii ATCC BAA-894 5550548 YP_001438792.1 CDS ESA_02724 NC_009778.1 2672888 2673502 D catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway; methylthioribulose-1-phosphate dehydratase 2672888..2673502 Cronobacter sakazakii ATCC BAA-894 5550496 YP_001438793.1 CDS ESA_02725 NC_009778.1 2673499 2674188 D KEGG: gbe:GbCGDNIH1_2267 2.5e-48 2,3-diketo-5-methylTHIo-1-phosphopentanoate tautomerase K01112; COG: COG4229 Predicted enolase-phosphatase; Psort location: cytoplasmic, score: 23; hypothetical protein 2673499..2674188 Cronobacter sakazakii ATCC BAA-894 5550545 YP_001438794.1 CDS ESA_02726 NC_009778.1 2674185 2674727 D KEGG: psp:PSPPH_1815 7.1e-51 ARD/ARD'''' family protein K05915; COG: COG1791 Uncharacterized conserved protein, contains double-stranded beta-helix domain; Psort location: cytoplasmic, score: 23; hypothetical protein 2674185..2674727 Cronobacter sakazakii ATCC BAA-894 5552260 YP_001438795.1 CDS entF NC_009778.1 2674954 2678835 R with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F complement(2674954..2678835) Cronobacter sakazakii ATCC BAA-894 5550560 YP_001438796.1 CDS ESA_02728 NC_009778.1 2678861 2679082 R COG: COG3251 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(2678861..2679082) Cronobacter sakazakii ATCC BAA-894 5550536 YP_001438797.1 CDS ESA_02729 NC_009778.1 2679086 2680330 R KEGG: btk:BT9727_2470 7.7e-15 probable esterase K07214; COG: COG2382 Enterochelin esterase and related enzymes; Psort location: cytoplasmic, score: 23; enterobactin/ferric enterobactin esterase complement(2679086..2680330) Cronobacter sakazakii ATCC BAA-894 5550572 YP_001438798.1 CDS ESA_02730 NC_009778.1 2680443 2682884 D Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 2680443..2682884 Cronobacter sakazakii ATCC BAA-894 5550554 YP_001438799.1 CDS ESA_02731 NC_009778.1 2682887 2683591 D KEGG: stt:t2284 1.7e-40 entD; enterobactin synthetase component D K02362; COG: COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein 2682887..2683591 Cronobacter sakazakii ATCC BAA-894 5550515 YP_001438800.1 CDS ESA_02732 NC_009778.1 2683560 2684279 R KEGG: bme:BMEII0002 1.5e-48 ribosomal-protein-serine acetyltransferase K00680; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2683560..2684279) Cronobacter sakazakii ATCC BAA-894 5550565 YP_001438801.1 CDS ESA_02733 NC_009778.1 2684457 2685572 D ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 2684457..2685572 Cronobacter sakazakii ATCC BAA-894 5550622 YP_001438802.1 CDS ESA_02734 NC_009778.1 2685828 2687744 D KEGG: pca:Pcar_2344 3.4e-06 nitrogen regulation protein NtrY, putative; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2685828..2687744 Cronobacter sakazakii ATCC BAA-894 5550635 YP_001438803.1 CDS ESA_02735 NC_009778.1 2688222 2688704 R COG: COG3518 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2688222..2688704) Cronobacter sakazakii ATCC BAA-894 5550638 YP_001438804.1 CDS ESA_02736 NC_009778.1 2688714 2689517 R COG: COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2688714..2689517) Cronobacter sakazakii ATCC BAA-894 5550595 YP_001438805.1 CDS ESA_02737 NC_009778.1 2689529 2690317 R COG: NOG25930 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2689529..2690317) Cronobacter sakazakii ATCC BAA-894 5550637 YP_001438806.1 CDS ESA_02738 NC_009778.1 2690323 2690583 R KEGG: cal:orf19.4072 0.0053 HYR10; similar to cell surface flocculin K01186; COG: NOG22390 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2690323..2690583) Cronobacter sakazakii ATCC BAA-894 5550605 YP_001438807.1 CDS ESA_02739 NC_009778.1 2690639 2693137 R KEGG: ago:ADR086C 1.1e-09 ADR086Cp; DNA-directed RNA polymerase II subunit A K03006; COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2690639..2693137) Cronobacter sakazakii ATCC BAA-894 5550732 YP_001438808.1 CDS ESA_02740 NC_009778.1 2693304 2694608 R KEGG: eci:UTI89_C0735 0.00070 tolA; membrane spanning protein TolA K03646; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2693304..2694608) Cronobacter sakazakii ATCC BAA-894 5550641 YP_001438809.1 CDS ESA_02741 NC_009778.1 2694978 2695874 R COG: COG2369 Uncharacterized protein, homolog of phage Mu protein gp30; Psort location: nuclear, score: 23; hypothetical protein complement(2694978..2695874) Cronobacter sakazakii ATCC BAA-894 5550774 YP_001438810.1 CDS ESA_02742 NC_009778.1 2695912 2696250 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2695912..2696250) Cronobacter sakazakii ATCC BAA-894 5550828 YP_001438811.1 CDS ESA_02743 NC_009778.1 2696382 2696813 R COG: COG1783 Phage terminase large subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2696382..2696813) Cronobacter sakazakii ATCC BAA-894 5550830 YP_001438812.1 CDS ESA_02744 NC_009778.1 2696797 2697249 R Psort location: nuclear, score: 23; hypothetical protein complement(2696797..2697249) Cronobacter sakazakii ATCC BAA-894 5550383 YP_001438813.1 CDS ESA_02745 NC_009778.1 2697253 2697489 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2697253..2697489) Cronobacter sakazakii ATCC BAA-894 5550338 YP_001438814.1 CDS ESA_02746 NC_009778.1 2697846 2698310 R KEGG: ecs:ECs1623 1.0e-33 putative endopeptidase K01423; COG: NOG19968 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(2697846..2698310) Cronobacter sakazakii ATCC BAA-894 5550642 YP_001438815.1 CDS ESA_02747 NC_009778.1 2698300 2698803 R KEGG: yps:YPTB1805 2.9e-47 probable endolysin (lysis protein) (lysozyme) K01185; COG: COG3772 Phage-related lysozyme (muraminidase); Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2698300..2698803) Cronobacter sakazakii ATCC BAA-894 5552442 YP_001438816.1 CDS ESA_02748 NC_009778.1 2698806 2699042 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2698806..2699042) Cronobacter sakazakii ATCC BAA-894 5550339 YP_001438817.1 CDS ESA_02749 NC_009778.1 2699270 2699551 D Psort location: cytoplasmic, score: 23; hypothetical protein 2699270..2699551 Cronobacter sakazakii ATCC BAA-894 5550343 YP_001438818.1 CDS ESA_02750 NC_009778.1 2699812 2700576 R COG: NOG09845 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2699812..2700576) Cronobacter sakazakii ATCC BAA-894 5550341 YP_001438819.1 CDS ESA_02751 NC_009778.1 2700573 2700752 R Psort location: nuclear, score: 23; hypothetical protein complement(2700573..2700752) Cronobacter sakazakii ATCC BAA-894 5550350 YP_001438820.1 CDS ESA_02752 NC_009778.1 2700749 2701006 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2700749..2701006) Cronobacter sakazakii ATCC BAA-894 5550329 YP_001438821.1 CDS ESA_02753 NC_009778.1 2701003 2701188 R KEGG: sec:SC0344 5.9e-24 rusA; Rus K01160; COG: COG4570 Holliday junction resolvase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2701003..2701188) Cronobacter sakazakii ATCC BAA-894 5550342 YP_001438822.1 CDS ESA_02754 NC_009778.1 2701202 2701447 D COG: COG0582 Integrase; Psort location: cytoplasmic, score: 23; hypothetical protein 2701202..2701447 Cronobacter sakazakii ATCC BAA-894 5550344 YP_001438823.1 CDS ESA_02756 NC_009778.1 2701748 2702614 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2701748..2702614 Cronobacter sakazakii ATCC BAA-894 5548815 YP_001438824.1 CDS ESA_02757 NC_009778.1 2702595 2702828 D COG: COG2501 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2702595..2702828 Cronobacter sakazakii ATCC BAA-894 5550320 YP_001438825.1 CDS ESA_02758 NC_009778.1 2703105 2704604 D KEGG: gka:GK0991 5.6e-122 PTS system, glucose-specific enzyme II, A component K02763:K02764:K02765; COG: COG2190 Phosphotransferase system IIA components; Psort location: plasma membrane, score: 23; hypothetical protein 2703105..2704604 Cronobacter sakazakii ATCC BAA-894 5550247 YP_001438826.1 CDS ESA_02759 NC_009778.1 2704669 2705685 D KEGG: efa:EF1922 3.1e-06 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 2704669..2705685 Cronobacter sakazakii ATCC BAA-894 5549899 YP_001438827.1 CDS ESA_02760 NC_009778.1 2705894 2707333 R KEGG: eci:UTI89_C0555 4.7e-228 cysS; cysteinyl-tRNA synthetase (cysteine--tRNA ligase) K01883; COG: COG0215 Cysteinyl-tRNA synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2705894..2707333) Cronobacter sakazakii ATCC BAA-894 5550240 YP_001438828.1 CDS ESA_02763 NC_009778.1 2707387 2707983 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2707387..2707983) Cronobacter sakazakii ATCC BAA-894 5550280 YP_001438829.1 CDS ESA_02761 NC_009778.1 2707456 2707950 D KEGG: eci:UTI89_C0554 2.6e-85 ppiB; peptidyl-prolyl cis-trans isomerase B (rotamase B) K03768; COG: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; Psort location: cytoplasmic, score: 23; peptidyl-prolyl cis-trans isomerase B (rotamase B) 2707456..2707950 Cronobacter sakazakii ATCC BAA-894 5550316 YP_001438830.1 CDS ESA_02762 NC_009778.1 2707954 2708676 D catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 2707954..2708676 Cronobacter sakazakii ATCC BAA-894 5550110 YP_001438831.1 CDS ESA_02764 NC_009778.1 2708809 2709318 D KEGG: stt:t2327 2.4e-73 purE; phosphoribosylaminoimidazole carboxylase catalytic subunit K01588; COG: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Psort location: cytoplasmic, score: 23; hypothetical protein 2708809..2709318 Cronobacter sakazakii ATCC BAA-894 5548816 YP_001438832.1 CDS ESA_02765 NC_009778.1 2709315 2710382 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 2709315..2710382 Cronobacter sakazakii ATCC BAA-894 5550096 YP_001438833.1 CDS ESA_02766 NC_009778.1 2710632 2711777 R KEGG: plu:plu0523 5.5e-147 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2710632..2711777) Cronobacter sakazakii ATCC BAA-894 5550217 YP_001438834.1 CDS ESA_02767 NC_009778.1 2711789 2713159 R KEGG: plu:plu0524 1.0e-163 unnamed protein product; similar to cystathionine beta-synthase K01697; COG: COG0031 Cysteine synthase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2711789..2713159) Cronobacter sakazakii ATCC BAA-894 5549981 YP_001438835.1 CDS ESA_02768 NC_009778.1 2713218 2713391 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2713218..2713391) Cronobacter sakazakii ATCC BAA-894 5550102 YP_001438836.1 CDS ESA_02769 NC_009778.1 2713495 2714628 D catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 2713495..2714628 Cronobacter sakazakii ATCC BAA-894 5548362 YP_001438837.1 CDS ESA_02770 NC_009778.1 2714618 2717032 R COG: COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component; Psort location: plasma membrane, score: 23; hypothetical protein complement(2714618..2717032) Cronobacter sakazakii ATCC BAA-894 5550235 YP_001438838.1 CDS ESA_02771 NC_009778.1 2717029 2717592 R KEGG: pen:PSEEN1885 4.6e-56 ABC transporter, ATP-binding protein; COG: COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2717029..2717592) Cronobacter sakazakii ATCC BAA-894 5549889 YP_001438839.1 CDS ESA_02772 NC_009778.1 2717653 2718312 D KEGG: eci:UTI89_C0529 3.2e-96 tesA; acyl-CoA THIoesterase I precursor K01048:K01076; COG: COG2755 Lysophospholipase L1 and related esterases; Psort location: extracellular, including cell wall, score: 23; multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 2717653..2718312 Cronobacter sakazakii ATCC BAA-894 5552448 YP_001438840.1 CDS ESA_02773 NC_009778.1 2718341 2719111 D KEGG: ecc:c0614 1.2e-110 ybbO; short chain dehydrogenase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; short chain dehydrogenase 2718341..2719111 Cronobacter sakazakii ATCC BAA-894 5548810 YP_001438841.1 CDS ESA_02774 NC_009778.1 2719170 2720024 D KEGG: eci:UTI89_C0527 6.2e-123 ybbN; putative THIoredoxin-like protein K05838; COG: COG3118 Thioredoxin domain-containing protein; Psort location: cytoplasmic, score: 23; hypothetical protein 2719170..2720024 Cronobacter sakazakii ATCC BAA-894 5550278 YP_001438842.1 CDS ESA_02775 NC_009778.1 2720134 2721051 D KEGG: reh:H16_A2036 1.7e-56 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2720134..2721051 Cronobacter sakazakii ATCC BAA-894 5552401 YP_001438843.1 CDS ESA_02776 NC_009778.1 2721048 2721503 D COG: COG1585 Membrane protein implicated in regulation of membrane protease activity; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2721048..2721503 Cronobacter sakazakii ATCC BAA-894 5552462 YP_001438844.1 CDS ESA_02777 NC_009778.1 2721549 2723741 D COG: NOG07908 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 2721549..2723741 Cronobacter sakazakii ATCC BAA-894 5552413 YP_001438845.1 CDS ESA_02778 NC_009778.1 2723711 2724430 D COG: NOG22395 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2723711..2724430 Cronobacter sakazakii ATCC BAA-894 5552367 YP_001438846.1 CDS ESA_02779 NC_009778.1 2724433 2724843 R KEGG: eci:UTI89_C3737 2.6e-14 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: nuclear, score: 23; hypothetical protein complement(2724433..2724843) Cronobacter sakazakii ATCC BAA-894 5552337 YP_001438847.1 CDS copA NC_009778.1 2724952 2727459 D KEGG: ecj:JW0473 0. copA; copper transporter K01533; COG: COG2217 Cation transport ATPase; Psort location: endoplasmic reticulum, score: 9; copper exporting ATPase 2724952..2727459 Cronobacter sakazakii ATCC BAA-894 5552369 YP_001438848.1 CDS ESA_02781 NC_009778.1 2727731 2728531 D COG: COG3735 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 2727731..2728531 Cronobacter sakazakii ATCC BAA-894 5552325 YP_001438849.1 CDS ESA_02783 NC_009778.1 2728733 2729212 D KEGG: gme:Gmet_1354 0.0067 prolyl-tRNA synthetase K01881; COG: COG2606 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 2728733..2729212 Cronobacter sakazakii ATCC BAA-894 5552312 YP_001438850.1 CDS ushA NC_009778.1 2729214 2730866 R catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor complement(2729214..2730866) Cronobacter sakazakii ATCC BAA-894 5552295 YP_001438851.1 CDS ESA_02785 NC_009778.1 2731105 2731326 R Psort location: nuclear, score: 23; hypothetical protein complement(2731105..2731326) Cronobacter sakazakii ATCC BAA-894 5552307 YP_001438852.1 CDS ESA_02786 NC_009778.1 2731387 2733069 D YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein 2731387..2733069 Cronobacter sakazakii ATCC BAA-894 5552273 YP_001438853.1 CDS ESA_02787 NC_009778.1 2733323 2734627 R KEGG: ecc:c0597 4.5e-216 gsk; inosine-guanosine kinase K00892; COG: COG0524 Sugar kinases, ribokinase family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2733323..2734627) Cronobacter sakazakii ATCC BAA-894 5552280 YP_001438854.1 CDS hemH NC_009778.1 2734691 2735653 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(2734691..2735653) Cronobacter sakazakii ATCC BAA-894 5552201 YP_001438855.1 CDS ESA_02789 NC_009778.1 2735774 2736928 R KEGG: yps:YPTB3821 9.1e-138 glxK; putative glycerate kinase K00865; COG: COG1929 Glycerate kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2735774..2736928) Cronobacter sakazakii ATCC BAA-894 5552225 YP_001438856.1 CDS ESA_02790 NC_009778.1 2736939 2738204 R KEGG: eci:UTI89_C3106 5.4e-21 ygbN; hypothetical permease YgbN K03299; COG: COG2610 H+/gluconate symporter and related permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(2736939..2738204) Cronobacter sakazakii ATCC BAA-894 5552209 YP_001438857.1 CDS ESA_02791 NC_009778.1 2738325 2739458 R KEGG: shn:Shewana3_2682 4.7e-63 transcriptional regulator, CdaR K01694; COG: COG3835 Sugar diacid utilization regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2738325..2739458) Cronobacter sakazakii ATCC BAA-894 5552223 YP_001438858.1 CDS adk NC_009778.1 2739593 2740252 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(2739593..2740252) Cronobacter sakazakii ATCC BAA-894 5552202 YP_001438859.1 CDS ESA_02793 NC_009778.1 2740678 2742552 R molecular chaperone; heat shock protein 90 complement(2740678..2742552) Cronobacter sakazakii ATCC BAA-894 5552206 YP_001438860.1 CDS recR NC_009778.1 2742710 2743315 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(2742710..2743315) Cronobacter sakazakii ATCC BAA-894 5552097 YP_001438861.1 CDS ESA_02795 NC_009778.1 2743390 2744475 R COG: NOG23921 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2743390..2744475) Cronobacter sakazakii ATCC BAA-894 5552149 YP_001438862.1 CDS ESA_02796 NC_009778.1 2744524 2745051 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2744524..2745051) Cronobacter sakazakii ATCC BAA-894 5552131 YP_001438863.1 CDS ESA_02797 NC_009778.1 2745128 2747617 R KEGG: eci:UTI89_C4143 0.0035 putative autotransport adhesin K01423; COG: COG3188 P pilus assembly protein, porin PapC; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2745128..2747617) Cronobacter sakazakii ATCC BAA-894 5552196 YP_001438864.1 CDS ESA_02798 NC_009778.1 2747713 2748390 R COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2747713..2748390) Cronobacter sakazakii ATCC BAA-894 5552144 YP_001438865.1 CDS ESA_02799 NC_009778.1 2748430 2748966 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2748430..2748966) Cronobacter sakazakii ATCC BAA-894 5552174 YP_001438866.1 CDS ESA_02800 NC_009778.1 2749330 2749662 R COG: COG0718 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2749330..2749662) Cronobacter sakazakii ATCC BAA-894 5552170 YP_001438867.1 CDS ESA_02801 NC_009778.1 2751797 2752348 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(2751797..2752348) Cronobacter sakazakii ATCC BAA-894 5552297 YP_001438868.1 CDS ESA_02802 NC_009778.1 2752500 2752877 R COG: COG2832 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2752500..2752877) Cronobacter sakazakii ATCC BAA-894 5551859 YP_001438869.1 CDS ESA_02803 NC_009778.1 2752944 2753459 D COG: COG3923 Primosomal replication protein N; Psort location: mitochondrial, score: 23; hypothetical protein 2752944..2753459 Cronobacter sakazakii ATCC BAA-894 5552349 YP_001438870.1 CDS ESA_02804 NC_009778.1 2753464 2753634 D COG: NOG22666 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2753464..2753634 Cronobacter sakazakii ATCC BAA-894 5552267 YP_001438871.1 CDS ESA_02805 NC_009778.1 2753674 2757129 R small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA complement(2753674..2757129) Cronobacter sakazakii ATCC BAA-894 5552461 YP_001438872.1 CDS ESA_02806 NC_009778.1 2757162 2757827 R regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR complement(2757162..2757827) Cronobacter sakazakii ATCC BAA-894 5552428 YP_001438873.1 CDS ESA_02807 NC_009778.1 2757972 2759177 D COG: COG0845 Membrane-fusion protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2757972..2759177 Cronobacter sakazakii ATCC BAA-894 5552381 YP_001438874.1 CDS ESA_02808 NC_009778.1 2759199 2762348 D KEGG: eci:UTI89_C2351 1.1e-107 yegO; hypothetical protein YegO K07789; COG: COG0841 Cation/multidrug efflux pump; Psort location: plasma membrane, score: 23; hypothetical protein 2759199..2762348 Cronobacter sakazakii ATCC BAA-894 5550254 YP_001438875.1 CDS ESA_02809 NC_009778.1 2762811 2763185 D COG: NOG09846 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2762811..2763185 Cronobacter sakazakii ATCC BAA-894 5549892 YP_001438876.1 CDS ESA_02810 NC_009778.1 2763212 2763430 D with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 2763212..2763430 Cronobacter sakazakii ATCC BAA-894 5549999 YP_001438877.1 CDS ESA_02811 NC_009778.1 2763579 2764190 D KEGG: sty:STY0515 7.7e-70 maA; maltose O-acetyltransferase K00661; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: mitochondrial, score: 23; maltose O-acetyltransferase 2763579..2764190 Cronobacter sakazakii ATCC BAA-894 5549967 YP_001438878.1 CDS ESA_02812 NC_009778.1 2764310 2764819 D COG: NOG07873 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2764310..2764819 Cronobacter sakazakii ATCC BAA-894 5548948 YP_001438879.1 CDS ESA_02813 NC_009778.1 2764848 2764988 R COG: COG0257 Ribosomal protein L36; Psort location: nuclear, score: 23; hypothetical protein complement(2764848..2764988) Cronobacter sakazakii ATCC BAA-894 5549976 YP_001438880.1 CDS ESA_02814 NC_009778.1 2764992 2765288 R COG: COG0254 Ribosomal protein L31; Psort location: nuclear, score: 23; hypothetical protein complement(2764992..2765288) Cronobacter sakazakii ATCC BAA-894 5549968 YP_001438881.1 CDS ESA_02815 NC_009778.1 2765392 2767329 R KEGG: vfi:VFA0360 3.1e-09 sensory transduction protein kinase; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2765392..2767329) Cronobacter sakazakii ATCC BAA-894 5550833 YP_001438882.1 CDS ESA_02816 NC_009778.1 2767651 2768688 D KEGG: cal:orf19.541 1.8e-45 similar to bacterial enzymes of the iron/ascorbate oxidoreductase family K00475; COG: COG3491 Isopenicillin N synthase and related dioxygenases; Psort location: cytoplasmic, score: 23; hypothetical protein 2767651..2768688 Cronobacter sakazakii ATCC BAA-894 5548268 YP_001438883.1 CDS ESA_02817 NC_009778.1 2768710 2769513 D COG: COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2768710..2769513 Cronobacter sakazakii ATCC BAA-894 5548131 YP_001438884.1 CDS ESA_02818 NC_009778.1 2769510 2770301 D KEGG: rru:Rru_A0788 5.8e-72 ABC transporter component K06020; COG: COG1135 ABC-type metal ion transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 2769510..2770301 Cronobacter sakazakii ATCC BAA-894 5548476 YP_001438885.1 CDS ESA_02819 NC_009778.1 2770298 2770957 D KEGG: baa:BA_0884 7.0e-44 binding-protein-dependent transport systems inner membrane component K00294; COG: COG2011 ABC-type metal ion transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2770298..2770957 Cronobacter sakazakii ATCC BAA-894 5548247 YP_001438886.1 CDS ESA_02820 NC_009778.1 2771035 2772678 D KEGG: mca:MCA1246 3.9e-32 methyltransferase CheR, putative K03412:K00575; COG: COG4943 Predicted signal transduction protein containing sensor and EAL domains; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2771035..2772678 Cronobacter sakazakii ATCC BAA-894 5548473 YP_001438887.1 CDS ESA_02821 NC_009778.1 2772671 2773504 R KEGG: sth:STH2923 5.8e-12 ribosomal-protein-alanine acetyltransferase K03789; COG: COG0456 Acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2772671..2773504) Cronobacter sakazakii ATCC BAA-894 5548305 YP_001438888.1 CDS ESA_02822 NC_009778.1 2773555 2774193 R KEGG: fal:FRAAL1741 0.00028 putative ABC transporter ATP-binding protein; COG: COG2364 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2773555..2774193) Cronobacter sakazakii ATCC BAA-894 5548438 YP_001438889.1 CDS ESA_02823 NC_009778.1 2774259 2775680 D KEGG: rha:RHA1_ro05556 3.1e-105 transcriptional regulator/aminotransferase; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: mitochondrial, score: 23; hypothetical protein 2774259..2775680 Cronobacter sakazakii ATCC BAA-894 5548461 YP_001438890.1 CDS ESA_02824 NC_009778.1 2775684 2775812 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2775684..2775812) Cronobacter sakazakii ATCC BAA-894 5548302 YP_001438891.1 CDS ESA_02826 NC_009778.1 2776056 2776277 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2776056..2776277) Cronobacter sakazakii ATCC BAA-894 5548191 YP_001438892.1 CDS ESA_02825 NC_009778.1 2776059 2776214 D Psort location: cytoplasmic, score: 23; hypothetical protein 2776059..2776214 Cronobacter sakazakii ATCC BAA-894 5548355 YP_001438893.1 CDS ESA_02827 NC_009778.1 2776274 2776525 R Psort location: nuclear, score: 23; hypothetical protein complement(2776274..2776525) Cronobacter sakazakii ATCC BAA-894 5548416 YP_001438894.1 CDS ESA_02829 NC_009778.1 2776932 2777087 D Psort location: mitochondrial, score: 23; hypothetical protein 2776932..2777087 Cronobacter sakazakii ATCC BAA-894 5548220 YP_001438895.1 CDS ESA_02830 NC_009778.1 2777297 2777755 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2777297..2777755) Cronobacter sakazakii ATCC BAA-894 5548386 YP_001438896.1 CDS ESA_02831 NC_009778.1 2779817 2780110 R COG: NOG14044 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2779817..2780110) Cronobacter sakazakii ATCC BAA-894 5548210 YP_001438897.1 CDS ESA_02832 NC_009778.1 2780110 2781027 R COG: COG1518 Uncharacterized protein predicted to be involved in DNA repair; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2780110..2781027) Cronobacter sakazakii ATCC BAA-894 5548264 YP_001438898.1 CDS ESA_02833 NC_009778.1 2781024 2781674 R COG: NOG14131 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2781024..2781674) Cronobacter sakazakii ATCC BAA-894 5548116 YP_001438899.1 CDS ESA_02834 NC_009778.1 2781656 2782408 R COG: NOG11452 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2781656..2782408) Cronobacter sakazakii ATCC BAA-894 5548110 YP_001438900.1 CDS ESA_02835 NC_009778.1 2782418 2783491 R COG: NOG07898 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2782418..2783491) Cronobacter sakazakii ATCC BAA-894 5552385 YP_001438901.1 CDS ESA_02836 NC_009778.1 2783503 2784108 R COG: NOG19581 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2783503..2784108) Cronobacter sakazakii ATCC BAA-894 5548425 YP_001438902.1 CDS ESA_02837 NC_009778.1 2784109 2785740 R COG: NOG07915 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2784109..2785740) Cronobacter sakazakii ATCC BAA-894 5548202 YP_001438903.1 CDS ESA_02838 NC_009778.1 2786031 2788664 R KEGG: afu:AF0071 4.4e-10 ATP-dependent RNA helicase, putative; COG: COG1203 Predicted helicases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2786031..2788664) Cronobacter sakazakii ATCC BAA-894 5548383 YP_001438904.1 CDS ESA_02839 NC_009778.1 2788870 2789181 D KEGG: eci:UTI89_C0482 8.1e-43 ybaZ; hypothetical protein YbaZ K07443; COG: COG3695 Predicted methylated DNA-protein cysteine methyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 2788870..2789181 Cronobacter sakazakii ATCC BAA-894 5552330 YP_001438905.1 CDS ESA_02840 NC_009778.1 2789213 2789827 R COG: COG3126 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2789213..2789827) Cronobacter sakazakii ATCC BAA-894 5548318 YP_001438906.1 CDS ESA_02841 NC_009778.1 2790011 2790871 D KEGG: ecs:ECs0506 1.0e-136 acyl-CoA THIoesterase II K01076; COG: COG1946 Acyl-CoA THIoesterase; Psort location: cytoplasmic, score: 23; acyl-CoA thioesterase II 2790011..2790871 Cronobacter sakazakii ATCC BAA-894 5548245 YP_001438907.1 CDS ESA_02842 NC_009778.1 2791141 2792436 R KEGG: ter:Tery_3993 1.0e-37 adenylate/guanylate cyclase K01769; COG: COG0004 Ammonia permease; Psort location: endoplasmic reticulum, score: 9; ammonium transporter complement(2791141..2792436) Cronobacter sakazakii ATCC BAA-894 5548203 YP_001438908.1 CDS ESA_02843 NC_009778.1 2792459 2792797 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 complement(2792459..2792797) Cronobacter sakazakii ATCC BAA-894 5548218 YP_001438909.1 CDS ESA_02844 NC_009778.1 2793029 2794807 R KEGG: cch:Cag_0453 1.0e-74 ATPase K06147; COG: COG1132 ABC-type multidrug transport system, ATPase and permease components; Psort location: endoplasmic reticulum, score: 9; putative multidrug transporter membrane\ATP-binding components complement(2793029..2794807) Cronobacter sakazakii ATCC BAA-894 5548412 YP_001438910.1 CDS ESA_02845 NC_009778.1 2794800 2796227 R KEGG: reh:H16_A0776 2.9e-70 ABC-type transporter, ATPase and permease components: Prot2E family; COG: COG1132 ABC-type multidrug transport system, ATPase and permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2794800..2796227) Cronobacter sakazakii ATCC BAA-894 5548364 YP_001438911.1 CDS ESA_02846 NC_009778.1 2796264 2796557 D Psort location: nuclear, score: 23; hypothetical protein 2796264..2796557 Cronobacter sakazakii ATCC BAA-894 5548135 YP_001438912.1 CDS ESA_02847 NC_009778.1 2796633 2797094 R COG: COG1522 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2796633..2797094) Cronobacter sakazakii ATCC BAA-894 5548158 YP_001438913.1 CDS ESA_02848 NC_009778.1 2797210 2798256 D KEGG: sec:SC0500 2.2e-152 putative cysteine synthase/cystathionine beta-synthase K01738; COG: COG0031 Cysteine synthase; Psort location: cytoplasmic, score: 23; hypothetical protein 2797210..2798256 Cronobacter sakazakii ATCC BAA-894 5548284 YP_001438914.1 CDS ESA_02849 NC_009778.1 2798651 2799088 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2798651..2799088 Cronobacter sakazakii ATCC BAA-894 5548091 YP_001438915.1 CDS ESA_02850 NC_009778.1 2799085 2801589 D KEGG: nma:NMA0905 3.0e-22 iga; IgA1 protease K01347; COG: KOG4809 Rab6 GTPase-interacting protein involved in endosome-to-TGN transport; Psort location: nuclear, score: 23; hypothetical protein 2799085..2801589 Cronobacter sakazakii ATCC BAA-894 5548420 YP_001438916.1 CDS ESA_02851 NC_009778.1 2801629 2802447 R KEGG: btl:BALH_4896 9.9e-22 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2801629..2802447) Cronobacter sakazakii ATCC BAA-894 5548120 YP_001438917.1 CDS ESA_02852 NC_009778.1 2802539 2804269 D COG: COG4533 ABC-type uncharacterized transport system, periplasmic component; Psort location: mitochondrial, score: 23; hypothetical protein 2802539..2804269 Cronobacter sakazakii ATCC BAA-894 5548174 YP_001438918.1 CDS ESA_02853 NC_009778.1 2804299 2804994 D YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 2804299..2804994 Cronobacter sakazakii ATCC BAA-894 5548156 YP_001438919.1 CDS ESA_02854 NC_009778.1 2804987 2805793 R KEGG: nph:NP3970A 1.7e-07 hydrolase (probable hydroxyacylglutathione hydrolase) 3 K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2804987..2805793) Cronobacter sakazakii ATCC BAA-894 5548451 YP_001438920.1 CDS ESA_02855 NC_009778.1 2807827 2808225 R KEGG: gbe:GbCGDNIH1_1102 6.4e-11 short-chain acyl-CoA hydrolase; COG: COG0824 Predicted THIoesterase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2807827..2808225) Cronobacter sakazakii ATCC BAA-894 5548335 YP_001438921.1 CDS ESA_02856 NC_009778.1 2808349 2808717 R KEGG: bur:Bcep18194_A5099 7.1e-05 RNA binding S1; COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2808349..2808717) Cronobacter sakazakii ATCC BAA-894 5548376 YP_001438922.1 CDS ESA_02857 NC_009778.1 2808864 2810741 R KEGG: sdy:SDY_0291 2.1e-232 ybaU; putative protease maturation protein K03770; COG: COG0760 Parvulin-like peptidyl-prolyl isomerase; Psort location: endoplasmic reticulum, score: 9; peptidyl-prolyl cis-trans isomerase (rotamase D) complement(2808864..2810741) Cronobacter sakazakii ATCC BAA-894 5548267 YP_001438923.1 CDS ESA_02858 NC_009778.1 2810957 2811229 R histone-like DNA-binding protein; transcriptional regulator HU subunit beta complement(2810957..2811229) Cronobacter sakazakii ATCC BAA-894 5548402 YP_001438924.1 CDS ESA_02859 NC_009778.1 2811439 2813793 R KEGG: spt:SPA2272 1.3e-266 lon; Lon protease K01338; COG: COG0466 ATP-dependent Lon protease, bacterial type; Psort location: cytoplasmic, score: 23; DNA-binding ATP-dependent protease La complement(2811439..2813793) Cronobacter sakazakii ATCC BAA-894 5548196 YP_001438925.1 CDS clpX NC_009778.1 2813980 2815254 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(2813980..2815254) Cronobacter sakazakii ATCC BAA-894 5548329 YP_001438926.1 CDS ESA_02861 NC_009778.1 2815378 2815962 R KEGG: sty:STY0490 8.7e-94 clpP; ATP-dependent clp protease proteolytic subunit K01358; COG: COG0740 Protease subunit of ATP-dependent Clp proteases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2815378..2815962) Cronobacter sakazakii ATCC BAA-894 5548444 YP_001438927.1 CDS tig NC_009778.1 2816302 2817600 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(2816302..2817600) Cronobacter sakazakii ATCC BAA-894 5548310 YP_001438928.1 CDS ESA_02863 NC_009778.1 2817605 2817748 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2817605..2817748) Cronobacter sakazakii ATCC BAA-894 5548092 YP_001438929.1 CDS ESA_02864 NC_009778.1 2817764 2817946 D Psort location: nuclear, score: 23; hypothetical protein 2817764..2817946 Cronobacter sakazakii ATCC BAA-894 5548238 YP_001438930.1 CDS ESA_02865 NC_009778.1 2817951 2818286 R positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA complement(2817951..2818286) Cronobacter sakazakii ATCC BAA-894 5548136 YP_001438931.1 CDS ESA_02866 NC_009778.1 2818567 2819145 D COG: COG3056 Uncharacterized lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2818567..2819145 Cronobacter sakazakii ATCC BAA-894 5548179 YP_001438932.1 CDS ampG NC_009778.1 2819200 2820684 D in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 2819200..2820684 Cronobacter sakazakii ATCC BAA-894 5548508 YP_001438933.1 CDS ESA_02868 NC_009778.1 2820673 2822013 R COG: NOG21760 non supervised orthologous group; Psort location: plasma membrane, score: 23; hypothetical protein complement(2820673..2822013) Cronobacter sakazakii ATCC BAA-894 5548419 YP_001438934.1 CDS ESA_02869 NC_009778.1 2822013 2823713 R KEGG: mbo:Mb0358 4.1e-87 dnaK; probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kda protein) (HSP70) K04043; COG: COG0443 Molecular chaperone; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2822013..2823713) Cronobacter sakazakii ATCC BAA-894 5552348 YP_001438935.1 CDS ESA_02870 NC_009778.1 2824234 2825181 D KEGG: eci:UTI89_C0456 2.6e-149 cyoA; cytochrome o ubiquinol oxidase subunit II K02297; COG: COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; Psort location: endoplasmic reticulum, score: 9; cytochrome o ubiquinol oxidase subunit II 2824234..2825181 Cronobacter sakazakii ATCC BAA-894 5548739 YP_001438936.1 CDS ESA_02871 NC_009778.1 2825201 2827192 D KEGG: eco:b0431 0. cyoB; cytochrome o ubiquinol oxidase subunit I K02298; COG: COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Psort location: plasma membrane, score: 23; hypothetical protein 2825201..2827192 Cronobacter sakazakii ATCC BAA-894 5548424 YP_001438937.1 CDS ESA_02872 NC_009778.1 2827182 2827799 D KEGG: sty:STY0483 9.9e-93 cyoC; cytochrome o ubiquinol oxidase subunit III K02299; COG: COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; Psort location: endoplasmic reticulum, score: 9; cytochrome o ubiquinol oxidase subunit III 2827182..2827799 Cronobacter sakazakii ATCC BAA-894 5548721 YP_001438938.1 CDS ESA_02873 NC_009778.1 2827799 2828128 D KEGG: eci:UTI89_C0452 1.2e-41 cyoD; cytochrome o ubiquinol oxidase protein CyoD K02300; COG: COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2827799..2828128 Cronobacter sakazakii ATCC BAA-894 5548784 YP_001438939.1 CDS ESA_02874 NC_009778.1 2828140 2829027 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 2828140..2829027 Cronobacter sakazakii ATCC BAA-894 5548296 YP_001438940.1 CDS ESA_02875 NC_009778.1 2829199 2830563 D KEGG: shn:Shewana3_1692 1.1e-07 Xaa-His dipeptidase K01270; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 2829199..2830563 Cronobacter sakazakii ATCC BAA-894 5548283 YP_001438941.1 CDS ESA_02876 NC_009778.1 2830628 2831119 R COG: COG1666 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2830628..2831119) Cronobacter sakazakii ATCC BAA-894 5548175 YP_001438942.1 CDS ESA_02877 NC_009778.1 2831272 2832186 D KEGG: sty:STY0473 4.3e-115 apbA; 2-dehydropantoate 2-reductase K00077; COG: COG1893 Ketopantoate reductase; Psort location: cytoplasmic, score: 23; hypothetical protein 2831272..2832186 Cronobacter sakazakii ATCC BAA-894 5548406 YP_001438943.1 CDS ESA_02878 NC_009778.1 2832146 2832739 D KEGG: eci:UTI89_C0447 2.9e-86 THIJ; 4-methyl-5(B-hydroxyethyl)-THIazole monophosphate biosynthesis enzyme K03152; COG: COG0693 Putative intracellular protease/amidase; Psort location: cytoplasmic, score: 23; DJ-1 family protein 2832146..2832739 Cronobacter sakazakii ATCC BAA-894 5548304 YP_001438944.1 CDS ESA_02879 NC_009778.1 2832818 2834431 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(2832818..2834431) Cronobacter sakazakii ATCC BAA-894 5548265 YP_001438945.1 CDS ESA_02880 NC_009778.1 2834478 2834720 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2834478..2834720 Cronobacter sakazakii ATCC BAA-894 5548403 YP_001438946.1 CDS ESA_02881 NC_009778.1 2834723 2835622 D KEGG: sty:STY0462 1.0e-122 ispA; geranyltranstransferase K00795; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: cytoplasmic, score: 23; geranyltranstransferase 2834723..2835622 Cronobacter sakazakii ATCC BAA-894 5548246 YP_001438947.1 CDS ESA_02882 NC_009778.1 2835649 2837511 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2835649..2837511 Cronobacter sakazakii ATCC BAA-894 5548227 YP_001438948.1 CDS ESA_02883 NC_009778.1 2837581 2838555 D KEGG: eco:b0419 2.9e-148 yajO; predicted oxidoreductase, NAD(P)-binding; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 2837581..2838555 Cronobacter sakazakii ATCC BAA-894 5548493 YP_001438949.1 CDS ESA_02884 NC_009778.1 2838597 2838995 R KEGG: sty:STY0459 1.8e-70 phosphatidylglycerophosphatase A K01095; COG: COG1267 Phosphatidylglycerophosphatase A and related proteins; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2838597..2838995) Cronobacter sakazakii ATCC BAA-894 5548224 YP_001438950.1 CDS ESA_02885 NC_009778.1 2839093 2840205 R catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase complement(2839093..2840205) Cronobacter sakazakii ATCC BAA-894 5551767 YP_001438951.1 CDS nusB NC_009778.1 2840260 2840679 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(2840260..2840679) Cronobacter sakazakii ATCC BAA-894 5548272 YP_001438952.1 CDS ribH NC_009778.1 2840701 2841171 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(2840701..2841171) Cronobacter sakazakii ATCC BAA-894 5548351 YP_001438953.1 CDS ribD NC_009778.1 2841259 2842362 R riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase complement(2841259..2842362) Cronobacter sakazakii ATCC BAA-894 5548281 YP_001438954.1 CDS nrdR NC_009778.1 2842366 2842815 R KEGG: eci:UTI89_C0435 3.6e-72 ybaD; hypothetical protein K07738; COG: COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; Psort location: cytoplasmic, score: 23; transcriptional regulator NrdR complement(2842366..2842815) Cronobacter sakazakii ATCC BAA-894 5548300 YP_001438955.1 CDS ESA_02890 NC_009778.1 2842907 2843530 D COG: NOG07872 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 2842907..2843530 Cronobacter sakazakii ATCC BAA-894 5548344 YP_001438956.1 CDS ESA_02891 NC_009778.1 2843871 2844749 D COG: COG3248 Nucleoside-binding outer membrane protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2843871..2844749 Cronobacter sakazakii ATCC BAA-894 5548437 YP_001438957.1 CDS ESA_02892 NC_009778.1 2844800 2844964 D Psort location: nuclear, score: 23; hypothetical protein 2844800..2844964 Cronobacter sakazakii ATCC BAA-894 5548213 YP_001438958.1 CDS secF NC_009778.1 2844943 2845914 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(2844943..2845914) Cronobacter sakazakii ATCC BAA-894 5548359 YP_001438959.1 CDS secD NC_009778.1 2845925 2847739 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(2845925..2847739) Cronobacter sakazakii ATCC BAA-894 5548343 YP_001438960.1 CDS yajC NC_009778.1 2847800 2848132 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(2847800..2848132) Cronobacter sakazakii ATCC BAA-894 5548563 YP_001438961.1 CDS tgt NC_009778.1 2848154 2849293 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(2848154..2849293) Cronobacter sakazakii ATCC BAA-894 5548459 YP_001438962.1 CDS queA NC_009778.1 2849393 2850463 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(2849393..2850463) Cronobacter sakazakii ATCC BAA-894 5548635 YP_001438963.1 CDS ESA_02898 NC_009778.1 2850565 2851146 D Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 2850565..2851146 Cronobacter sakazakii ATCC BAA-894 5548427 YP_001438964.1 CDS ESA_02899 NC_009778.1 2851147 2852517 R COG: NOG14010 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2851147..2852517) Cronobacter sakazakii ATCC BAA-894 5548608 YP_001438965.1 CDS ESA_02900 NC_009778.1 2852514 2855240 R KEGG: sma:SAV6022 1.8e-05 sucB; putative dihydrolipoamide S-succinyltransferase K00658; COG: COG5373 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(2852514..2855240) Cronobacter sakazakii ATCC BAA-894 5548348 YP_001438966.1 CDS ESA_02901 NC_009778.1 2855325 2857142 R KEGG: eci:UTI89_C0425 2.7e-234 malZ; maltodextrin glucosidase K01187; COG: COG0366 Glycosidases; Psort location: extracellular, including cell wall, score: 9; maltodextrin glucosidase complement(2855325..2857142) Cronobacter sakazakii ATCC BAA-894 5548262 YP_001438967.1 CDS proY NC_009778.1 2857311 2858678 R cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease complement(2857311..2858678) Cronobacter sakazakii ATCC BAA-894 5548319 YP_001438968.1 CDS ESA_02903 NC_009778.1 2858749 2860068 R KEGG: rpb:RPB_2641 0.00046 V-type H(+)-translocating pyrophosphatase K01507; COG: COG1114 Branched-chain amino acid permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(2858749..2860068) Cronobacter sakazakii ATCC BAA-894 5548377 YP_001438969.1 CDS phoR NC_009778.1 2860467 2861780 R membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein complement(2860467..2861780) Cronobacter sakazakii ATCC BAA-894 5548371 YP_001438970.1 CDS ESA_02905 NC_009778.1 2861803 2862492 R two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB complement(2861803..2862492) Cronobacter sakazakii ATCC BAA-894 5548430 YP_001438971.1 CDS ESA_02906 NC_009778.1 2862691 2863905 D with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 2862691..2863905 Cronobacter sakazakii ATCC BAA-894 5548439 YP_001438972.1 CDS ESA_02907 NC_009778.1 2863902 2867051 D with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 2863902..2867051 Cronobacter sakazakii ATCC BAA-894 5548515 YP_001438973.1 CDS ESA_02908 NC_009778.1 2867091 2868002 R KEGG: rru:Rru_A2630 1.2e-85 ROK K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2867091..2868002) Cronobacter sakazakii ATCC BAA-894 5548724 YP_001438974.1 CDS rdgC NC_009778.1 2868090 2869040 D Required for efficient pilin antigenic variation; recombination associated protein 2868090..2869040 Cronobacter sakazakii ATCC BAA-894 5548559 YP_001438975.1 CDS ESA_02910 NC_009778.1 2869074 2869358 R COG: COG3123 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2869074..2869358) Cronobacter sakazakii ATCC BAA-894 5548704 YP_001438976.1 CDS ESA_02911 NC_009778.1 2869442 2870119 R COG: NOG06193 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(2869442..2870119) Cronobacter sakazakii ATCC BAA-894 5548521 YP_001438977.1 CDS ESA_02912 NC_009778.1 2870292 2870603 D Psort location: cytoplasmic, score: 23; hypothetical protein 2870292..2870603 Cronobacter sakazakii ATCC BAA-894 5548790 YP_001438978.1 CDS ESA_02913 NC_009778.1 2870379 2870570 R COG: NOG13867 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(2870379..2870570) Cronobacter sakazakii ATCC BAA-894 5548533 YP_001438979.1 CDS ESA_02914 NC_009778.1 2870623 2871147 R KEGG: sec:SC0429 5.9e-56 aroL; shikimate kinase II K00891; COG: COG0703 Shikimate kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2870623..2871147) Cronobacter sakazakii ATCC BAA-894 5548505 YP_001438980.1 CDS ESA_02915 NC_009778.1 2871509 2872285 D COG: COG3416 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 2871509..2872285 Cronobacter sakazakii ATCC BAA-894 5548593 YP_001438981.1 CDS ESA_02916 NC_009778.1 2872282 2872737 R COG: COG1671 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2872282..2872737) Cronobacter sakazakii ATCC BAA-894 5548792 YP_001438982.1 CDS ESA_02917 NC_009778.1 2872737 2873192 R COG: COG2323 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2872737..2873192) Cronobacter sakazakii ATCC BAA-894 5548619 YP_001438983.1 CDS ESA_02918 NC_009778.1 2873202 2873717 R COG: NOG18327 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2873202..2873717) Cronobacter sakazakii ATCC BAA-894 5548601 YP_001438984.1 CDS ESA_02919 NC_009778.1 2873796 2874638 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 2873796..2874638 Cronobacter sakazakii ATCC BAA-894 5548571 YP_001438985.1 CDS ESA_02920 NC_009778.1 2874676 2876094 R KEGG: cal:orf19.3526 2.2e-56 ITR2; myo-inositol transporter K08140; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(2874676..2876094) Cronobacter sakazakii ATCC BAA-894 5548616 YP_001438986.1 CDS ESA_02921 NC_009778.1 2876139 2876267 D Psort location: cytoplasmic, score: 23; hypothetical protein 2876139..2876267 Cronobacter sakazakii ATCC BAA-894 5548553 YP_001438987.1 CDS ESA_02922 NC_009778.1 2876431 2876628 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2876431..2876628) Cronobacter sakazakii ATCC BAA-894 5548565 YP_001438988.1 CDS ESA_02923 NC_009778.1 2876748 2877095 R COG: NOG14126 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2876748..2877095) Cronobacter sakazakii ATCC BAA-894 5548490 YP_001438989.1 CDS ESA_02924 NC_009778.1 2877232 2878425 R KEGG: ace:Acel_1971 2.3e-08 dTMP kinase K00943; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2877232..2878425) Cronobacter sakazakii ATCC BAA-894 5548514 YP_001438990.1 CDS ESA_02925 NC_009778.1 2878587 2879288 R COG: COG3921 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2878587..2879288) Cronobacter sakazakii ATCC BAA-894 5548575 YP_001438991.1 CDS ESA_02926 NC_009778.1 2879433 2880533 D KEGG: ecs:ECs0431 8.4e-151 D-alanine-D-alanine ligase K01921; COG: COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; Psort location: cytoskeletal, score: 9; hypothetical protein 2879433..2880533 Cronobacter sakazakii ATCC BAA-894 5548486 YP_001438992.1 CDS ESA_02927 NC_009778.1 2880544 2880798 R COG: NOG09786 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2880544..2880798) Cronobacter sakazakii ATCC BAA-894 5548612 YP_001438993.1 CDS ESA_02928 NC_009778.1 2881115 2881420 D COG: NOG11448 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2881115..2881420 Cronobacter sakazakii ATCC BAA-894 5552440 YP_001438994.1 CDS ESA_02929 NC_009778.1 2881417 2882523 R COG: NOG06003 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(2881417..2882523) Cronobacter sakazakii ATCC BAA-894 5548679 YP_001438995.1 CDS ESA_02930 NC_009778.1 2882620 2883840 R in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein complement(2882620..2883840) Cronobacter sakazakii ATCC BAA-894 5548618 YP_001438996.1 CDS ESA_02931 NC_009778.1 2884017 2884529 R KEGG: bma:BMAA0508 1.4e-24 isochorismatase family protein K05993; COG: COG1335 Amidases related to nicotinamidase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2884017..2884529) Cronobacter sakazakii ATCC BAA-894 5548651 YP_001438997.1 CDS ESA_02932 NC_009778.1 2884750 2885907 D this protein has no known enzymatic function; beta-lactam binding protein AmpH 2884750..2885907 Cronobacter sakazakii ATCC BAA-894 5548636 YP_001438998.1 CDS ESA_02933 NC_009778.1 2885942 2886568 R COG: NOG06782 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2885942..2886568) Cronobacter sakazakii ATCC BAA-894 5548564 YP_001438999.1 CDS ESA_02934 NC_009778.1 2886650 2889427 R KEGG: eci:UTI89_C0334 2.3e-52 hypothetical protein; COG: COG3468 Type V secretory pathway, adhesin AidA; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2886650..2889427) Cronobacter sakazakii ATCC BAA-894 5548592 YP_001439000.1 CDS ESA_02935 NC_009778.1 2889808 2890323 D COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Psort location: cytoplasmic, score: 23; hypothetical protein 2889808..2890323 Cronobacter sakazakii ATCC BAA-894 5548708 YP_001439001.1 CDS ESA_02936 NC_009778.1 2890533 2891447 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2890533..2891447 Cronobacter sakazakii ATCC BAA-894 5548710 YP_001439002.1 CDS ESA_02937 NC_009778.1 2891585 2893303 D KEGG: oih:OB0869 7.9e-06 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG3176 Putative hemolysin; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2891585..2893303 Cronobacter sakazakii ATCC BAA-894 5548538 YP_001439003.1 CDS ESA_02938 NC_009778.1 2893802 2894194 R COG: NOG18699 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(2893802..2894194) Cronobacter sakazakii ATCC BAA-894 5548552 YP_001439004.1 CDS tauD NC_009778.1 2894351 2895202 R catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase complement(2894351..2895202) Cronobacter sakazakii ATCC BAA-894 5548489 YP_001439005.1 CDS ESA_02940 NC_009778.1 2895199 2896026 R KEGG: rha:RHA1_ro08170 3.8e-20 ABC transporter, permease component; COG: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; Psort location: endoplasmic reticulum, score: 9; taurine transporter subunit complement(2895199..2896026) Cronobacter sakazakii ATCC BAA-894 5548561 YP_001439006.1 CDS tauB NC_009778.1 2896010 2896789 R Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit complement(2896010..2896789) Cronobacter sakazakii ATCC BAA-894 5548580 YP_001439007.1 CDS ESA_02942 NC_009778.1 2896799 2897776 R COG: COG4521 ABC-type taurine transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2896799..2897776) Cronobacter sakazakii ATCC BAA-894 5548491 YP_001439008.1 CDS mmuM NC_009778.1 2898368 2899300 R converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase complement(2898368..2899300) Cronobacter sakazakii ATCC BAA-894 5548570 YP_001439009.1 CDS ESA_02944 NC_009778.1 2899287 2900687 R KEGG: eci:UTI89_C0120 1.5e-75 aroP; aromatic amino acid transport protein AroP K03293; COG: COG0833 Amino acid transporters; Psort location: plasma membrane, score: 23; S-methylmethionine transporter complement(2899287..2900687) Cronobacter sakazakii ATCC BAA-894 5550834 YP_001439010.1 CDS ESA_02945 NC_009778.1 2900970 2903942 D KEGG: xcb:XC_1452 0. formate dehydrogenase related protein K00123; COG: COG3383 Uncharacterized anaerobic dehydrogenase; Psort location: cytoplasmic, score: 23; hypothetical protein 2900970..2903942 Cronobacter sakazakii ATCC BAA-894 5548594 YP_001439011.1 CDS ESA_02946 NC_009778.1 2903942 2904430 D COG: NOG39140 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 2903942..2904430 Cronobacter sakazakii ATCC BAA-894 5550797 YP_001439012.1 CDS ESA_02947 NC_009778.1 2904433 2905845 D KEGG: xcc:XCC2662 1.4e-157 qxtA; cytochrome D oxidase subunit A K00425; COG: COG1271 Cytochrome bd-type quinol oxidase, subunit 1; Psort location: plasma membrane, score: 23; hypothetical protein 2904433..2905845 Cronobacter sakazakii ATCC BAA-894 5548484 YP_001439013.1 CDS ESA_02948 NC_009778.1 2905838 2906860 D KEGG: xcc:XCC2661 1.7e-74 qxtB; cytochrome D oxidase subunit B K00426; COG: COG1294 Cytochrome bd-type quinol oxidase, subunit 2; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2905838..2906860 Cronobacter sakazakii ATCC BAA-894 5548689 YP_001439014.1 CDS ESA_02949 NC_009778.1 2907138 2907296 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2907138..2907296 Cronobacter sakazakii ATCC BAA-894 5548375 YP_001439015.1 CDS ESA_02950 NC_009778.1 2907391 2908419 R KEGG: reh:H16_A2322 6.2e-36 ATPase K01529; COG: COG1485 Predicted ATPase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2907391..2908419) Cronobacter sakazakii ATCC BAA-894 5550540 YP_001439016.1 CDS ESA_02951 NC_009778.1 2908554 2909477 R KEGG: ecp:ECP_2404 6.6e-119 putative acyltransferase K00680; COG: COG1560 Lauroyl/myristoyl acyltransferase; Psort location: mitochondrial, score: 23; hypothetical protein complement(2908554..2909477) Cronobacter sakazakii ATCC BAA-894 5550832 YP_001439017.1 CDS ESA_02952 NC_009778.1 2910082 2910249 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2910082..2910249) Cronobacter sakazakii ATCC BAA-894 5548734 YP_001439018.1 CDS ESA_02953 NC_009778.1 2910367 2911122 R COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2910367..2911122) Cronobacter sakazakii ATCC BAA-894 5548782 YP_001439019.1 CDS ESA_02954 NC_009778.1 2911155 2911790 D KEGG: bur:Bcep18194_A4044 3.0e-68 nucleoside diphosphate pyrophosphatase K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 2911155..2911790 Cronobacter sakazakii ATCC BAA-894 5548950 YP_001439020.1 CDS ESA_02955 NC_009778.1 2911801 2912160 D KEGG: pfl:PFL_3331 7.7e-22 nudF; ADP-ribose pyrophosphatase K01515; COG: NOG33362 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2911801..2912160 Cronobacter sakazakii ATCC BAA-894 5548762 YP_001439021.1 CDS ESA_02956 NC_009778.1 2912219 2913436 R COG: COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2912219..2913436) Cronobacter sakazakii ATCC BAA-894 5548777 YP_001439022.1 CDS ESA_02957 NC_009778.1 2913740 2914189 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2913740..2914189) Cronobacter sakazakii ATCC BAA-894 5548663 YP_001439023.1 CDS ESA_02958 NC_009778.1 2914424 2914561 D Psort location: mitochondrial, score: 23; hypothetical protein 2914424..2914561 Cronobacter sakazakii ATCC BAA-894 5548745 YP_001439024.1 CDS ESA_02959 NC_009778.1 2914718 2915341 D KEGG: eca:ECA3327 2.2e-40 putative carbonic anhydrase K01673; COG: COG0288 Carbonic anhydrase; Psort location: cytoplasmic, score: 23; hypothetical protein 2914718..2915341 Cronobacter sakazakii ATCC BAA-894 5548657 YP_001439025.1 CDS ESA_02960 NC_009778.1 2915338 2916807 D KEGG: bpm:BURPS1710b_1425 3.0e-107 sul1; sulfate transporter family protein K01672; COG: COG0659 Sulfate permease and related transporters (MFS superfamily); Psort location: plasma membrane, score: 23; hypothetical protein 2915338..2916807 Cronobacter sakazakii ATCC BAA-894 5548771 YP_001439026.1 CDS ESA_02961 NC_009778.1 2916955 2918043 D KEGG: tbd:Tbd_2668 1.1e-06 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: plasma membrane, score: 23; hypothetical protein 2916955..2918043 Cronobacter sakazakii ATCC BAA-894 5548722 YP_001439027.1 CDS ESA_02962 NC_009778.1 2918220 2920652 D KEGG: atc:AGR_L_2936 0. probable quinate dehydrogenase K00117; COG: COG4993 Glucose dehydrogenase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2918220..2920652 Cronobacter sakazakii ATCC BAA-894 5548525 YP_001439028.1 CDS ESA_02963 NC_009778.1 2920706 2921641 R KEGG: shn:Shewana3_3435 1.4e-08 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2920706..2921641) Cronobacter sakazakii ATCC BAA-894 5548642 YP_001439029.1 CDS ESA_02964 NC_009778.1 2921740 2922174 D COG: NOG23817 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2921740..2922174 Cronobacter sakazakii ATCC BAA-894 5548772 YP_001439030.1 CDS ESA_02965 NC_009778.1 2922184 2922651 D COG: COG3238 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2922184..2922651 Cronobacter sakazakii ATCC BAA-894 5548686 YP_001439031.1 CDS ESA_02966 NC_009778.1 2922629 2923501 R KEGG: shn:Shewana3_3435 0.00086 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2922629..2923501) Cronobacter sakazakii ATCC BAA-894 5548743 YP_001439032.1 CDS ESA_02967 NC_009778.1 2923568 2924107 D KEGG: eca:ECA0069 4.3e-76 padC, pad; phenolic acid decarboxylase K01618; COG: COG3479 Phenolic acid decarboxylase; Psort location: cytoplasmic, score: 23; hypothetical protein 2923568..2924107 Cronobacter sakazakii ATCC BAA-894 5548764 YP_001439033.1 CDS ESA_02968 NC_009778.1 2924258 2925913 D KEGG: pto:PTO0598 3.3e-62 glucoamylase K01178; COG: COG3387 Glucoamylase and related glycosyl hydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein 2924258..2925913 Cronobacter sakazakii ATCC BAA-894 5548760 YP_001439034.1 CDS ESA_02969 NC_009778.1 2925910 2926083 D Psort location: nuclear, score: 23; hypothetical protein 2925910..2926083 Cronobacter sakazakii ATCC BAA-894 5548693 YP_001439035.1 CDS ESA_02970 NC_009778.1 2926136 2926939 R COG: COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2926136..2926939) Cronobacter sakazakii ATCC BAA-894 5548718 YP_001439036.1 CDS ESA_02971 NC_009778.1 2926961 2927629 R KEGG: baa:BA_0884 1.3e-37 binding-protein-dependent transport systems inner membrane component K00294; COG: COG2011 ABC-type metal ion transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2926961..2927629) Cronobacter sakazakii ATCC BAA-894 5548676 YP_001439037.1 CDS ESA_02972 NC_009778.1 2927622 2928644 R KEGG: rru:Rru_A0788 4.4e-83 ABC transporter component K06020; COG: COG1135 ABC-type metal ion transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2927622..2928644) Cronobacter sakazakii ATCC BAA-894 5548730 YP_001439038.1 CDS ESA_02973 NC_009778.1 2928886 2930865 R KEGG: reh:H16_A0369 5.6e-99 rfbB1; dTDP-D-glucose 4,6-dehydratase K01710; COG: COG3211 Predicted phosphatase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2928886..2930865) Cronobacter sakazakii ATCC BAA-894 5548750 YP_001439039.1 CDS ESA_02974 NC_009778.1 2931078 2931335 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2931078..2931335 Cronobacter sakazakii ATCC BAA-894 5552081 YP_001439040.1 CDS ESA_02975 NC_009778.1 2931387 2933165 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(2931387..2933165) Cronobacter sakazakii ATCC BAA-894 5548577 YP_001439041.1 CDS ESA_02976 NC_009778.1 2933299 2934564 R COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(2933299..2934564) Cronobacter sakazakii ATCC BAA-894 5548583 YP_001439042.1 CDS lacZ NC_009778.1 2934634 2937765 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(2934634..2937765) Cronobacter sakazakii ATCC BAA-894 5548613 YP_001439043.1 CDS lacI NC_009778.1 2937924 2939087 D transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 2937924..2939087 Cronobacter sakazakii ATCC BAA-894 5548660 YP_001439044.1 CDS ESA_02979 NC_009778.1 2939091 2939993 R KEGG: reh:H16_B2351 1.0e-35 short-chain dehydrogenase of various substrate specificities; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein complement(2939091..2939993) Cronobacter sakazakii ATCC BAA-894 5548725 YP_001439045.1 CDS ESA_02980 NC_009778.1 2940328 2940675 D COG: NOG18146 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2940328..2940675 Cronobacter sakazakii ATCC BAA-894 5548751 YP_001439046.1 CDS ESA_02981 NC_009778.1 2940907 2941494 R COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2940907..2941494) Cronobacter sakazakii ATCC BAA-894 5551081 YP_001439047.1 CDS ESA_02982 NC_009778.1 2941637 2942041 D KEGG: ape:APE_1501.1 1.9e-09 ribonuclease UK114; COG: COG0251 Putative translation initiation inhibitor, yjgF family; Psort location: cytoplasmic, score: 23; hypothetical protein 2941637..2942041 Cronobacter sakazakii ATCC BAA-894 5548661 YP_001439048.1 CDS ESA_02983 NC_009778.1 2942088 2943098 R KEGG: sth:STH1645 1.7e-111 glyceraldehyde-3-phosphate dehydrogenase K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2942088..2943098) Cronobacter sakazakii ATCC BAA-894 5548716 YP_001439049.1 CDS ESA_02984 NC_009778.1 2943177 2944157 R KEGG: bpm:BURPS1710b_A2214 9.1e-35 ftrA; transcriptional activator FtrA K00356; COG: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2943177..2944157) Cronobacter sakazakii ATCC BAA-894 5548735 YP_001439050.1 CDS ESA_02985 NC_009778.1 2944341 2944796 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2944341..2944796 Cronobacter sakazakii ATCC BAA-894 5548649 YP_001439051.1 CDS ESA_02986 NC_009778.1 2944404 2944700 R Psort location: nuclear, score: 23; hypothetical protein complement(2944404..2944700) Cronobacter sakazakii ATCC BAA-894 5548496 YP_001439052.1 CDS ESA_02988 NC_009778.1 2944682 2944840 R Psort location: nuclear, score: 23; hypothetical protein complement(2944682..2944840) Cronobacter sakazakii ATCC BAA-894 5552214 YP_001439053.1 CDS ESA_02987 NC_009778.1 2944812 2945003 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2944812..2945003 Cronobacter sakazakii ATCC BAA-894 5548804 YP_001439054.1 CDS ESA_02989 NC_009778.1 2945057 2945503 R COG: NOG27561 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2945057..2945503) Cronobacter sakazakii ATCC BAA-894 5548488 YP_001439055.1 CDS ESA_02990 NC_009778.1 2945496 2946299 R COG: NOG26268 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2945496..2946299) Cronobacter sakazakii ATCC BAA-894 5548646 YP_001439056.1 CDS ESA_02991 NC_009778.1 2946455 2946586 D Psort location: nuclear, score: 23; hypothetical protein 2946455..2946586 Cronobacter sakazakii ATCC BAA-894 5548788 YP_001439057.1 CDS ESA_02992 NC_009778.1 2946826 2947884 D KEGG: mlo:mll3679 4.6e-88 membrane dipeptidase K01273; COG: COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog; Psort location: cytoplasmic, score: 23; hypothetical protein 2946826..2947884 Cronobacter sakazakii ATCC BAA-894 5548638 YP_001439058.1 CDS ESA_02993 NC_009778.1 2948131 2949039 D possibly involved in transport of pyrroloquinoline quinone transport; pyrroloquinoline quinone biosynthesis protein PqqB 2948131..2949039 Cronobacter sakazakii ATCC BAA-894 5548715 YP_001439059.1 CDS ESA_02994 NC_009778.1 2949048 2949803 D Required in the synthesis of PPQ, but its exact function is unknown; pyrroloquinoline quinone biosynthesis protein PqqC 2949048..2949803 Cronobacter sakazakii ATCC BAA-894 5548763 YP_001439060.1 CDS ESA_02995 NC_009778.1 2949803 2950081 D COG: NOG16986 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2949803..2950081 Cronobacter sakazakii ATCC BAA-894 5548372 YP_001439061.1 CDS ESA_02996 NC_009778.1 2950074 2951210 D KEGG: dar:Daro_2097 6.6e-07 radical SAM K04069; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: cytoplasmic, score: 23; pyrroloquinoline quinone biosynthesis protein PqqE 2950074..2951210 Cronobacter sakazakii ATCC BAA-894 5548736 YP_001439062.1 CDS ESA_02997 NC_009778.1 2951207 2953351 D KEGG: pae:PA1973 3.5e-74 pqqF; pyrroloquinoline quinone biosynthesis protein F; COG: COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; Psort location: mitochondrial, score: 23; hypothetical protein 2951207..2953351 Cronobacter sakazakii ATCC BAA-894 5548701 YP_001439063.1 CDS ESA_02998 NC_009778.1 2953562 2955157 R KEGG: shn:Shewana3_2650 2.1e-125 acetate kinase K00925; COG: COG0747 ABC-type dipeptide transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2953562..2955157) Cronobacter sakazakii ATCC BAA-894 5548778 YP_001439064.1 CDS ESA_02999 NC_009778.1 2955170 2956504 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 2955170..2956504 Cronobacter sakazakii ATCC BAA-894 5548670 YP_001439065.1 CDS ESA_03000 NC_009778.1 2956515 2956796 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2956515..2956796) Cronobacter sakazakii ATCC BAA-894 5548680 YP_001439066.1 CDS ESA_03002 NC_009778.1 2956899 2957369 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2956899..2957369) Cronobacter sakazakii ATCC BAA-894 5548574 YP_001439067.1 CDS ESA_03001 NC_009778.1 2957089 2957295 D Psort location: nuclear, score: 23; hypothetical protein 2957089..2957295 Cronobacter sakazakii ATCC BAA-894 5548706 YP_001439068.1 CDS ESA_03003 NC_009778.1 2957396 2957575 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2957396..2957575) Cronobacter sakazakii ATCC BAA-894 5548755 YP_001439069.1 CDS ESA_03004 NC_009778.1 2957576 2957773 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2957576..2957773) Cronobacter sakazakii ATCC BAA-894 5548645 YP_001439070.1 CDS ESA_03005 NC_009778.1 2957814 2958752 D COG: NOG35673 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 2957814..2958752 Cronobacter sakazakii ATCC BAA-894 5548641 YP_001439071.1 CDS ESA_03006 NC_009778.1 2958749 2959192 D COG: COG3755 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2958749..2959192 Cronobacter sakazakii ATCC BAA-894 5548747 YP_001439072.1 CDS ESA_03007 NC_009778.1 2959236 2959697 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2959236..2959697 Cronobacter sakazakii ATCC BAA-894 5548975 YP_001439073.1 CDS ESA_03008 NC_009778.1 2959764 2960207 D Psort location: mitochondrial, score: 23; hypothetical protein 2959764..2960207 Cronobacter sakazakii ATCC BAA-894 5548946 YP_001439074.1 CDS ESA_03009 NC_009778.1 2960351 2960794 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2960351..2960794 Cronobacter sakazakii ATCC BAA-894 5548967 YP_001439075.1 CDS ESA_03010 NC_009778.1 2960874 2961338 R COG: NOG27449 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2960874..2961338) Cronobacter sakazakii ATCC BAA-894 5549024 YP_001439076.1 CDS ESA_03011 NC_009778.1 2961958 2962629 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2961958..2962629) Cronobacter sakazakii ATCC BAA-894 5548806 YP_001439077.1 CDS ESA_03012 NC_009778.1 2962630 2962881 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2962630..2962881) Cronobacter sakazakii ATCC BAA-894 5548963 YP_001439078.1 CDS ESA_03013 NC_009778.1 2963034 2963183 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2963034..2963183) Cronobacter sakazakii ATCC BAA-894 5552288 YP_001439079.1 CDS ESA_03014 NC_009778.1 2964314 2964820 R KEGG: lpl:lp_1289 0.00020 adenine phosphoribosyltransferase; Psort location: nuclear, score: 23; hypothetical protein complement(2964314..2964820) Cronobacter sakazakii ATCC BAA-894 5548947 YP_001439080.1 CDS ESA_03015 NC_009778.1 2965547 2966524 R COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2965547..2966524) Cronobacter sakazakii ATCC BAA-894 5548990 YP_001439081.1 CDS ESA_03016 NC_009778.1 2966988 2967125 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2966988..2967125) Cronobacter sakazakii ATCC BAA-894 5548766 YP_001439082.1 CDS ESA_03017 NC_009778.1 2967150 2967422 R COG: NOG22117 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(2967150..2967422) Cronobacter sakazakii ATCC BAA-894 5552395 YP_001439083.1 CDS ESA_03018 NC_009778.1 2967702 2970137 R KEGG: sty:STY4832 2.1e-22 Bacteriophage P4 DNA primase; COG: COG5519 Superfamily II helicase and inactivated derivatives; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2967702..2970137) Cronobacter sakazakii ATCC BAA-894 5548830 YP_001439084.1 CDS ESA_03020 NC_009778.1 2970386 2970796 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2970386..2970796) Cronobacter sakazakii ATCC BAA-894 5548915 YP_001439085.1 CDS ESA_03019 NC_009778.1 2970780 2970914 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2970780..2970914 Cronobacter sakazakii ATCC BAA-894 5548944 YP_001439086.1 CDS ESA_03021 NC_009778.1 2970786 2971019 R Psort location: nuclear, score: 23; hypothetical protein complement(2970786..2971019) Cronobacter sakazakii ATCC BAA-894 5548785 YP_001439087.1 CDS ESA_03022 NC_009778.1 2971685 2972686 R COG: NOG06079 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2971685..2972686) Cronobacter sakazakii ATCC BAA-894 5548835 YP_001439088.1 CDS ESA_03023 NC_009778.1 2972705 2973574 R Psort location: nuclear, score: 23; hypothetical protein complement(2972705..2973574) Cronobacter sakazakii ATCC BAA-894 5548982 YP_001439089.1 CDS ESA_03024 NC_009778.1 2973942 2974736 R Psort location: mitochondrial, score: 23; hypothetical protein complement(2973942..2974736) Cronobacter sakazakii ATCC BAA-894 5548824 YP_001439090.1 CDS ESA_03025 NC_009778.1 2974743 2975924 R COG: COG0582 Integrase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2974743..2975924) Cronobacter sakazakii ATCC BAA-894 5548870 YP_001439091.1 CDS ESA_03026 NC_009778.1 2976325 2976687 D COG: COG2246 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2976325..2976687 Cronobacter sakazakii ATCC BAA-894 5548868 YP_001439092.1 CDS ESA_03027 NC_009778.1 2976684 2977613 D KEGG: eco:b2351 1.1e-146 yfdH; CPS-53 (KpLE1) prophage; putative bactoprenol glucosyl transferase K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: vacuolar, score: 9; hypothetical protein 2976684..2977613 Cronobacter sakazakii ATCC BAA-894 5548833 YP_001439093.1 CDS ESA_03028 NC_009778.1 2977610 2979088 D COG: NOG37959 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 2977610..2979088 Cronobacter sakazakii ATCC BAA-894 5548818 YP_001439094.1 CDS ESA_03029 NC_009778.1 2979112 2981103 R COG: COG3210 Large exoproteins involved in heme utilization or adhesion; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2979112..2981103) Cronobacter sakazakii ATCC BAA-894 5548892 YP_001439095.1 CDS ESA_03030 NC_009778.1 2981160 2983637 R COG: NOG11915 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2981160..2983637) Cronobacter sakazakii ATCC BAA-894 5548801 YP_001439096.1 CDS ESA_03031 NC_009778.1 2983624 2984040 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2983624..2984040) Cronobacter sakazakii ATCC BAA-894 5548917 YP_001439097.1 CDS ESA_03032 NC_009778.1 2984003 2984473 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2984003..2984473) Cronobacter sakazakii ATCC BAA-894 5548900 YP_001439098.1 CDS ESA_03033 NC_009778.1 2984473 2984970 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2984473..2984970) Cronobacter sakazakii ATCC BAA-894 5548860 YP_001439099.1 CDS ESA_03034 NC_009778.1 2984970 2988452 R KEGG: azo:azo0200 6.0e-08 sbcC; exonuclease SbcC, putative K01146; COG: COG5281 Phage-related minor tail protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2984970..2988452) Cronobacter sakazakii ATCC BAA-894 5548849 YP_001439100.1 CDS ESA_03035 NC_009778.1 2988522 2989199 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(2988522..2989199) Cronobacter sakazakii ATCC BAA-894 5548492 YP_001439101.1 CDS ESA_03036 NC_009778.1 2989192 2989881 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2989192..2989881) Cronobacter sakazakii ATCC BAA-894 5550861 YP_001439102.1 CDS ESA_03037 NC_009778.1 2989878 2990471 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2989878..2990471) Cronobacter sakazakii ATCC BAA-894 5551129 YP_001439103.1 CDS ESA_03038 NC_009778.1 2990453 2991910 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2990453..2991910) Cronobacter sakazakii ATCC BAA-894 5548547 YP_001439104.1 CDS ESA_03039 NC_009778.1 2991950 2992444 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(2991950..2992444) Cronobacter sakazakii ATCC BAA-894 5548876 YP_001439105.1 CDS ESA_03040 NC_009778.1 2992464 2992577 R Psort location: nuclear, score: 23; hypothetical protein complement(2992464..2992577) Cronobacter sakazakii ATCC BAA-894 5548999 YP_001439106.1 CDS ESA_03041 NC_009778.1 2992468 2992851 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2992468..2992851) Cronobacter sakazakii ATCC BAA-894 5548949 YP_001439107.1 CDS ESA_03042 NC_009778.1 2992848 2993216 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2992848..2993216) Cronobacter sakazakii ATCC BAA-894 5549147 YP_001439108.1 CDS ESA_03043 NC_009778.1 2993218 2993568 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2993218..2993568) Cronobacter sakazakii ATCC BAA-894 5549095 YP_001439109.1 CDS ESA_03044 NC_009778.1 2993636 2994016 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2993636..2994016) Cronobacter sakazakii ATCC BAA-894 5549243 YP_001439110.1 CDS ESA_03045 NC_009778.1 2994019 2994216 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2994019..2994216) Cronobacter sakazakii ATCC BAA-894 5549411 YP_001439111.1 CDS ESA_03046 NC_009778.1 2994226 2995311 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2994226..2995311) Cronobacter sakazakii ATCC BAA-894 5549003 YP_001439112.1 CDS ESA_03047 NC_009778.1 2995324 2995752 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2995324..2995752) Cronobacter sakazakii ATCC BAA-894 5549577 YP_001439113.1 CDS ESA_03048 NC_009778.1 2995758 2997158 R KEGG: eci:UTI89_C0735 0.00078 tolA; membrane spanning protein TolA K03646; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2995758..2997158) Cronobacter sakazakii ATCC BAA-894 5549504 YP_001439114.1 CDS ESA_03049 NC_009778.1 2997210 2997557 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 2997210..2997557 Cronobacter sakazakii ATCC BAA-894 5550017 YP_001439115.1 CDS ESA_03050 NC_009778.1 2997561 2998454 R COG: COG2369 Uncharacterized protein, homolog of phage Mu protein gp30; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2997561..2998454) Cronobacter sakazakii ATCC BAA-894 5550074 YP_001439116.1 CDS ESA_03051 NC_009778.1 2998492 2999949 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(2998492..2999949) Cronobacter sakazakii ATCC BAA-894 5549958 YP_001439117.1 CDS ESA_03052 NC_009778.1 2999961 3001424 R COG: COG5410 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(2999961..3001424) Cronobacter sakazakii ATCC BAA-894 5550106 YP_001439118.1 CDS ESA_03053 NC_009778.1 3001411 3001968 R COG: COG3728 Phage terminase, small subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3001411..3001968) Cronobacter sakazakii ATCC BAA-894 5552392 YP_001439119.1 CDS ESA_03054 NC_009778.1 3002023 3002331 D Psort location: cytoplasmic, score: 23; hypothetical protein 3002023..3002331 Cronobacter sakazakii ATCC BAA-894 5549912 YP_001439120.1 CDS ESA_03055 NC_009778.1 3002387 3002587 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3002387..3002587) Cronobacter sakazakii ATCC BAA-894 5549956 YP_001439121.1 CDS ESA_03056 NC_009778.1 3002639 3002851 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3002639..3002851) Cronobacter sakazakii ATCC BAA-894 5549910 YP_001439122.1 CDS ESA_03057 NC_009778.1 3002961 3003488 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3002961..3003488) Cronobacter sakazakii ATCC BAA-894 5549902 YP_001439123.1 CDS ESA_03058 NC_009778.1 3003587 3004291 R COG: COG3645 Uncharacterized phage-encoded protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3003587..3004291) Cronobacter sakazakii ATCC BAA-894 5549942 YP_001439124.1 CDS ESA_03059 NC_009778.1 3004297 3004506 R Psort location: nuclear, score: 23; hypothetical protein complement(3004297..3004506) Cronobacter sakazakii ATCC BAA-894 5549897 YP_001439125.1 CDS ESA_03060 NC_009778.1 3004718 3004996 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3004718..3004996 Cronobacter sakazakii ATCC BAA-894 5549887 YP_001439126.1 CDS ESA_03061 NC_009778.1 3005155 3005520 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3005155..3005520) Cronobacter sakazakii ATCC BAA-894 5551847 YP_001439127.1 CDS ESA_03062 NC_009778.1 3005510 3006004 R KEGG: ecc:c1562 3.0e-43 ybcS; probable lysozyme from lambdoid prophage DLP12 K01185; COG: COG3772 Phage-related lysozyme (muraminidase); Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3005510..3006004) Cronobacter sakazakii ATCC BAA-894 5549894 YP_001439128.1 CDS ESA_03063 NC_009778.1 3006013 3006303 R COG: NOG38344 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3006013..3006303) Cronobacter sakazakii ATCC BAA-894 5551417 YP_001439129.1 CDS ESA_03064 NC_009778.1 3006480 3006710 D Psort location: cytoplasmic, score: 23; hypothetical protein 3006480..3006710 Cronobacter sakazakii ATCC BAA-894 5549901 YP_001439130.1 CDS ESA_03065 NC_009778.1 3006720 3006875 D Psort location: cytoplasmic, score: 23; hypothetical protein 3006720..3006875 Cronobacter sakazakii ATCC BAA-894 5549763 YP_001439131.1 CDS ESA_03067 NC_009778.1 3007582 3008199 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3007582..3008199) Cronobacter sakazakii ATCC BAA-894 5549757 YP_001439132.1 CDS ESA_03066 NC_009778.1 3007708 3007839 D Psort location: cytoplasmic, score: 23; hypothetical protein 3007708..3007839 Cronobacter sakazakii ATCC BAA-894 5549783 YP_001439133.1 CDS ESA_03068 NC_009778.1 3008196 3008375 R Psort location: nuclear, score: 23; hypothetical protein complement(3008196..3008375) Cronobacter sakazakii ATCC BAA-894 5549749 YP_001439134.1 CDS ESA_03069 NC_009778.1 3008372 3008629 R KEGG: sto:ST1438 0.0086 V-type H+-transporting ATPase subunit D K02120; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3008372..3008629) Cronobacter sakazakii ATCC BAA-894 5549794 YP_001439135.1 CDS ESA_03070 NC_009778.1 3008626 3009237 R COG: NOG14016 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(3008626..3009237) Cronobacter sakazakii ATCC BAA-894 5549858 YP_001439136.1 CDS ESA_03071 NC_009778.1 3009237 3009536 R Psort location: nuclear, score: 23; hypothetical protein complement(3009237..3009536) Cronobacter sakazakii ATCC BAA-894 5549871 YP_001439137.1 CDS ESA_03072 NC_009778.1 3009523 3009699 R Psort location: nuclear, score: 23; hypothetical protein complement(3009523..3009699) Cronobacter sakazakii ATCC BAA-894 5549860 YP_001439138.1 CDS ESA_03073 NC_009778.1 3009692 3010012 R COG: NOG23760 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3009692..3010012) Cronobacter sakazakii ATCC BAA-894 5549875 YP_001439139.1 CDS ESA_03074 NC_009778.1 3010103 3010324 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3010103..3010324) Cronobacter sakazakii ATCC BAA-894 5551836 YP_001439140.1 CDS ESA_03075 NC_009778.1 3010493 3010903 R COG: NOG18339 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(3010493..3010903) Cronobacter sakazakii ATCC BAA-894 5549874 YP_001439141.1 CDS ESA_03076 NC_009778.1 3010875 3011132 R COG: NOG22509 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3010875..3011132) Cronobacter sakazakii ATCC BAA-894 5551895 YP_001439142.1 CDS ESA_03077 NC_009778.1 3011132 3011389 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3011132..3011389) Cronobacter sakazakii ATCC BAA-894 5551950 YP_001439143.1 CDS ESA_03078 NC_009778.1 3011382 3011525 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3011382..3011525) Cronobacter sakazakii ATCC BAA-894 5549323 YP_001439144.1 CDS ESA_03080 NC_009778.1 3011527 3011997 R Psort location: nuclear, score: 23; hypothetical protein complement(3011527..3011997) Cronobacter sakazakii ATCC BAA-894 5549340 YP_001439145.1 CDS ESA_03079 NC_009778.1 3011770 3012030 D Psort location: cytoplasmic, score: 23; hypothetical protein 3011770..3012030 Cronobacter sakazakii ATCC BAA-894 5549366 YP_001439146.1 CDS ESA_03081 NC_009778.1 3012011 3012154 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3012011..3012154) Cronobacter sakazakii ATCC BAA-894 5549353 YP_001439147.1 CDS ESA_03082 NC_009778.1 3012145 3012981 R Psort location: nuclear, score: 23; hypothetical protein complement(3012145..3012981) Cronobacter sakazakii ATCC BAA-894 5550133 YP_001439148.1 CDS ESA_03083 NC_009778.1 3013205 3014605 R KEGG: ecs:ECs1190 2.6e-133 replication protein P K02314; COG: COG0305 Replicative DNA helicase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3013205..3014605) Cronobacter sakazakii ATCC BAA-894 5549369 YP_001439149.1 CDS ESA_03084 NC_009778.1 3014595 3015491 R COG: NOG24180 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(3014595..3015491) Cronobacter sakazakii ATCC BAA-894 5551661 YP_001439150.1 CDS ESA_03085 NC_009778.1 3015678 3015956 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3015678..3015956) Cronobacter sakazakii ATCC BAA-894 5549288 YP_001439151.1 CDS ESA_03086 NC_009778.1 3016403 3017065 D KEGG: tcx:Tcr_1234 2.8e-07 putative prophage repressor K01356; COG: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Psort location: cytoplasmic, score: 23; hypothetical protein 3016403..3017065 Cronobacter sakazakii ATCC BAA-894 5552409 YP_001439152.1 CDS ESA_03087 NC_009778.1 3017239 3017664 D Psort location: nuclear, score: 23; hypothetical protein 3017239..3017664 Cronobacter sakazakii ATCC BAA-894 5551519 YP_001439153.1 CDS ESA_03088 NC_009778.1 3017677 3018009 D Psort location: nuclear, score: 23; hypothetical protein 3017677..3018009 Cronobacter sakazakii ATCC BAA-894 5551575 YP_001439154.1 CDS ESA_03089 NC_009778.1 3018018 3018263 D Psort location: cytoplasmic, score: 23; hypothetical protein 3018018..3018263 Cronobacter sakazakii ATCC BAA-894 5548887 YP_001439155.1 CDS ESA_03090 NC_009778.1 3018313 3018567 D Psort location: cytoplasmic, score: 23; hypothetical protein 3018313..3018567 Cronobacter sakazakii ATCC BAA-894 5551989 YP_001439156.1 CDS ESA_03091 NC_009778.1 3018611 3018952 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3018611..3018952 Cronobacter sakazakii ATCC BAA-894 5551605 YP_001439157.1 CDS ESA_03092 NC_009778.1 3018953 3019195 D Psort location: cytoplasmic, score: 23; hypothetical protein 3018953..3019195 Cronobacter sakazakii ATCC BAA-894 5551325 YP_001439158.1 CDS ESA_03093 NC_009778.1 3019257 3019382 D Psort location: cytoplasmic, score: 23; hypothetical protein 3019257..3019382 Cronobacter sakazakii ATCC BAA-894 5551327 YP_001439159.1 CDS ESA_03094 NC_009778.1 3019590 3019721 D Psort location: cytoplasmic, score: 23; hypothetical protein 3019590..3019721 Cronobacter sakazakii ATCC BAA-894 5551323 YP_001439160.1 CDS ESA_03095 NC_009778.1 3019709 3019855 D Psort location: nuclear, score: 23; hypothetical protein 3019709..3019855 Cronobacter sakazakii ATCC BAA-894 5551983 YP_001439161.1 CDS ESA_03096 NC_009778.1 3019789 3020001 D Psort location: nuclear, score: 23; hypothetical protein 3019789..3020001 Cronobacter sakazakii ATCC BAA-894 5550269 YP_001439162.1 CDS ESA_03097 NC_009778.1 3019943 3020128 D Psort location: nuclear, score: 23; hypothetical protein 3019943..3020128 Cronobacter sakazakii ATCC BAA-894 5549217 YP_001439163.1 CDS ESA_03098 NC_009778.1 3020136 3020747 D Psort location: nuclear, score: 23; hypothetical protein 3020136..3020747 Cronobacter sakazakii ATCC BAA-894 5549404 YP_001439164.1 CDS ESA_03099 NC_009778.1 3020747 3021124 D Psort location: nuclear, score: 23; hypothetical protein 3020747..3021124 Cronobacter sakazakii ATCC BAA-894 5552272 YP_001439165.1 CDS ESA_03100 NC_009778.1 3021214 3021453 D Psort location: cytoplasmic, score: 23; hypothetical protein 3021214..3021453 Cronobacter sakazakii ATCC BAA-894 5549324 YP_001439166.1 CDS ESA_03101 NC_009778.1 3021464 3021625 D Psort location: nuclear, score: 23; hypothetical protein 3021464..3021625 Cronobacter sakazakii ATCC BAA-894 5549380 YP_001439167.1 CDS ESA_03102 NC_009778.1 3021622 3022134 D Psort location: cytoplasmic, score: 23; hypothetical protein 3021622..3022134 Cronobacter sakazakii ATCC BAA-894 5549331 YP_001439168.1 CDS ESA_03103 NC_009778.1 3022134 3022322 D Psort location: cytoplasmic, score: 23; hypothetical protein 3022134..3022322 Cronobacter sakazakii ATCC BAA-894 5552491 YP_001439169.1 CDS ESA_03104 NC_009778.1 3022675 3022929 D Psort location: cytoplasmic, score: 23; hypothetical protein 3022675..3022929 Cronobacter sakazakii ATCC BAA-894 5549347 YP_001439170.1 CDS ESA_03105 NC_009778.1 3022964 3023596 D Psort location: cytoplasmic, score: 23; hypothetical protein 3022964..3023596 Cronobacter sakazakii ATCC BAA-894 5549368 YP_001439171.1 CDS ESA_03106 NC_009778.1 3023718 3023990 D Psort location: cytoplasmic, score: 23; hypothetical protein 3023718..3023990 Cronobacter sakazakii ATCC BAA-894 5549941 YP_001439172.1 CDS ESA_03107 NC_009778.1 3024217 3025380 D COG: COG0582 Integrase; Psort location: cytoplasmic, score: 23; hypothetical protein 3024217..3025380 Cronobacter sakazakii ATCC BAA-894 5548345 YP_001439173.1 CDS proA NC_009778.1 3025579 3026832 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(3025579..3026832) Cronobacter sakazakii ATCC BAA-894 5548226 YP_001439174.1 CDS ESA_03110 NC_009778.1 3026843 3027946 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(3026843..3027946) Cronobacter sakazakii ATCC BAA-894 5552476 YP_001439175.1 CDS ESA_03111 NC_009778.1 3027939 3028070 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3027939..3028070) Cronobacter sakazakii ATCC BAA-894 5549241 YP_001439176.1 CDS ESA_03112 NC_009778.1 3028235 3029308 D COG: COG3203 Outer membrane protein (porin); Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3028235..3029308 Cronobacter sakazakii ATCC BAA-894 5552123 YP_001439177.1 CDS ESA_03113 NC_009778.1 3029430 3029843 R involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl complement(3029430..3029843) Cronobacter sakazakii ATCC BAA-894 5549374 YP_001439178.1 CDS frsA NC_009778.1 3029877 3031157 R forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein complement(3029877..3031157) Cronobacter sakazakii ATCC BAA-894 5551061 YP_001439179.1 CDS ESA_03115 NC_009778.1 3031232 3031690 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(3031232..3031690) Cronobacter sakazakii ATCC BAA-894 5549401 YP_001439180.1 CDS ESA_03116 NC_009778.1 3032059 3033408 D KEGG: stm:STM0316 2.0e-213 pepD; aminoacyl-histidine dipeptidase K01270; COG: COG2195 Di- and tripeptidases; Psort location: cytoplasmic, score: 23; hypothetical protein 3032059..3033408 Cronobacter sakazakii ATCC BAA-894 5549333 YP_001439181.1 CDS ESA_03117 NC_009778.1 3033645 3034700 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(3033645..3034700) Cronobacter sakazakii ATCC BAA-894 5549386 YP_001439182.1 CDS ESA_03118 NC_009778.1 3034956 3035693 D COG: COG3034 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3034956..3035693 Cronobacter sakazakii ATCC BAA-894 5549385 YP_001439183.1 CDS ESA_03119 NC_009778.1 3035664 3036431 R KEGG: reh:H16_A0476 5.6e-67 predicted glutamine amidotransferase class II; COG: COG0121 Predicted glutamine amidotransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3035664..3036431) Cronobacter sakazakii ATCC BAA-894 5549382 YP_001439184.1 CDS gmhA NC_009778.1 3036520 3037101 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(3036520..3037101) Cronobacter sakazakii ATCC BAA-894 5549345 YP_001439185.1 CDS fadE NC_009778.1 3037330 3039774 D functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 3037330..3039774 Cronobacter sakazakii ATCC BAA-894 5549416 YP_001439186.1 CDS ESA_03122 NC_009778.1 3039862 3040650 D KEGG: eco:b0219 1.4e-109 yafV; predicted C-N hydrolase family amidase, NAD(P)-binding; COG: COG0388 Predicted amidohydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein 3039862..3040650 Cronobacter sakazakii ATCC BAA-894 5550167 YP_001439187.1 CDS ESA_03124 NC_009778.1 3040949 3041680 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(3040949..3041680) Cronobacter sakazakii ATCC BAA-894 5549891 YP_001439188.1 CDS ESA_03125 NC_009778.1 3041733 3042209 D KEGG: ecp:ECP_0220 1.1e-75 ribonuclease HI K03469; COG: COG0328 Ribonuclease HI; Psort location: cytoplasmic, score: 23; hypothetical protein 3041733..3042209 Cronobacter sakazakii ATCC BAA-894 5549432 YP_001439189.1 CDS ESA_03126 NC_009778.1 3042206 3042922 R KEGG: vfi:VF1937 2.8e-40 methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3042206..3042922) Cronobacter sakazakii ATCC BAA-894 5549919 YP_001439190.1 CDS ESA_03127 NC_009778.1 3042955 3043710 D catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 3042955..3043710 Cronobacter sakazakii ATCC BAA-894 5552255 YP_001439191.1 CDS mltD NC_009778.1 3043782 3045155 D catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 3043782..3045155 Cronobacter sakazakii ATCC BAA-894 5549932 YP_001439192.1 CDS ESA_03129 NC_009778.1 3045217 3045993 R KEGG: eci:UTI89_C0229 1.2e-96 yafE; conserved hypothetical protein YafE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3045217..3045993) Cronobacter sakazakii ATCC BAA-894 5550063 YP_001439193.1 CDS ESA_03130 NC_009778.1 3046058 3046840 R COG: COG3021 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3046058..3046840) Cronobacter sakazakii ATCC BAA-894 5550126 YP_001439194.1 CDS ESA_03131 NC_009778.1 3047079 3047966 D KEGG: shn:Shewana3_3435 1.8e-11 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 3047079..3047966 Cronobacter sakazakii ATCC BAA-894 5550027 YP_001439195.1 CDS ESA_03132 NC_009778.1 3047985 3048788 R KEGG: sec:SC0251 1.7e-111 yafB; 2,5-diketo-D-gluconate reductase B K06222; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3047985..3048788) Cronobacter sakazakii ATCC BAA-894 5550004 YP_001439197.1 CDS ESA_03138 NC_009778.1 3054461 3055021 R Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase complement(3054461..3055021) Cronobacter sakazakii ATCC BAA-894 5550251 YP_001439198.1 CDS metN NC_009778.1 3055212 3056243 D part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 3055212..3056243 Cronobacter sakazakii ATCC BAA-894 5549473 YP_001439199.1 CDS ESA_03140 NC_009778.1 3056236 3056889 D part of the MetNIQ methionine uptake system; DL-methionine transporter permease subunit 3056236..3056889 Cronobacter sakazakii ATCC BAA-894 5549549 YP_001439200.1 CDS metQ NC_009778.1 3056926 3057747 D COG: COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Psort location: extracellular, including cell wall, score: 9; DL-methionine transporter substrate-binding subunit 3056926..3057747 Cronobacter sakazakii ATCC BAA-894 5550180 YP_001439201.1 CDS rcsF NC_009778.1 3057860 3058264 D COG: NOG09836 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; outer membrane lipoprotein 3057860..3058264 Cronobacter sakazakii ATCC BAA-894 5550181 YP_001439202.1 CDS ESA_03143 NC_009778.1 3058261 3058968 D KEGG: eci:UTI89_C0211 3.3e-101 yaeB; hypothetical protein YaeB; COG: COG1720 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3058261..3058968 Cronobacter sakazakii ATCC BAA-894 5549844 YP_001439203.1 CDS ESA_03144 NC_009778.1 3059079 3060797 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 3059079..3060797 Cronobacter sakazakii ATCC BAA-894 5549772 YP_001439204.1 CDS ESA_03145 NC_009778.1 3060867 3061565 R COG: COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance; Psort location: endoplasmic reticulum, score: 9; lipoprotein involved with copper homeostasis and adhesion complement(3060867..3061565) Cronobacter sakazakii ATCC BAA-894 5549700 YP_001439205.1 CDS ESA_03146 NC_009778.1 3061593 3062015 R KEGG: reh:H16_A3611 7.6e-31 pth2; peptidyl-tRNA hydrolase; COG: COG1186 Protein chain release factor B; Psort location: nuclear, score: 23; peptidyl-tRNA hydrolase domain protein complement(3061593..3062015) Cronobacter sakazakii ATCC BAA-894 5549446 YP_001439206.1 CDS ESA_03147 NC_009778.1 3062012 3062557 R KEGG: bpm:BURPS1710b_0319 2.3e-38 YaeQ protein K00356; COG: COG4681 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3062012..3062557) Cronobacter sakazakii ATCC BAA-894 5549604 YP_001439207.1 CDS ESA_03148 NC_009778.1 3062764 3062964 D COG: NOG13866 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3062764..3062964 Cronobacter sakazakii ATCC BAA-894 5549800 YP_001439208.1 CDS ESA_03149 NC_009778.1 3062957 3063211 D Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 3062957..3063211 Cronobacter sakazakii ATCC BAA-894 5549427 YP_001439209.1 CDS ESA_03150 NC_009778.1 3063259 3063573 R KEGG: cvi:CV4386 1.8e-15 cyc; cytochrome-c oxidase K00403; COG: COG2863 Cytochrome c553; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3063259..3063573) Cronobacter sakazakii ATCC BAA-894 5550171 YP_001439210.1 CDS ESA_03151 NC_009778.1 3063566 3064870 R KEGG: stm:STM0236 3.5e-136 mesJ; cell cycle protein K04075; COG: COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3063566..3064870) Cronobacter sakazakii ATCC BAA-894 5549701 YP_001439211.1 CDS ESA_03152 NC_009778.1 3064935 3065324 R KEGG: ecc:c0225 3.9e-59 yaeR; hypothetical protein YaeR K01759; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3064935..3065324) Cronobacter sakazakii ATCC BAA-894 5549372 YP_001439212.1 CDS ESA_03153 NC_009778.1 3065382 3067520 R KEGG: stt:t0236 0. ldcC; lysine decarboxylase K01582; COG: COG1982 Arginine/lysine/orniTHIne decarboxylases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3065382..3067520) Cronobacter sakazakii ATCC BAA-894 5549466 YP_001439213.1 CDS ESA_03154 NC_009778.1 3067667 3069424 R KEGG: bam:Bamb_1428 1.1e-27 chitinase K01183; COG: COG3979 Uncharacterized protein contain chitin-binding domain type 3; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3067667..3069424) Cronobacter sakazakii ATCC BAA-894 5549595 YP_001439214.1 CDS ESA_03156 NC_009778.1 3069588 3070547 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(3069588..3070547) Cronobacter sakazakii ATCC BAA-894 5549652 YP_001439215.1 CDS ESA_03155 NC_009778.1 3069720 3070706 D Psort location: cytoplasmic, score: 23; hypothetical protein 3069720..3070706 Cronobacter sakazakii ATCC BAA-894 5552230 YP_001439216.1 CDS dnaE NC_009778.1 3070651 3074133 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(3070651..3074133) Cronobacter sakazakii ATCC BAA-894 5549394 YP_001439217.1 CDS rnhB NC_009778.1 3074163 3074759 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(3074163..3074759) Cronobacter sakazakii ATCC BAA-894 5549684 YP_001439218.1 CDS lpxB NC_009778.1 3074756 3075898 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(3074756..3075898) Cronobacter sakazakii ATCC BAA-894 5549697 YP_001439219.1 CDS ESA_03160 NC_009778.1 3075898 3076686 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(3075898..3076686) Cronobacter sakazakii ATCC BAA-894 5549685 YP_001439220.1 CDS fabZ NC_009778.1 3076690 3077145 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(3076690..3077145) Cronobacter sakazakii ATCC BAA-894 5549788 YP_001439221.1 CDS ESA_03162 NC_009778.1 3077135 3077290 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3077135..3077290) Cronobacter sakazakii ATCC BAA-894 5550176 YP_001439222.1 CDS lpxD NC_009778.1 3077262 3078287 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(3077262..3078287) Cronobacter sakazakii ATCC BAA-894 5549853 YP_001439223.1 CDS ESA_03164 NC_009778.1 3078291 3078863 R COG: COG2825 Outer membrane protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3078291..3078863) Cronobacter sakazakii ATCC BAA-894 5549845 YP_001439224.1 CDS ESA_03165 NC_009778.1 3078908 3081322 R part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT complement(3078908..3081322) Cronobacter sakazakii ATCC BAA-894 5550200 YP_001439225.1 CDS ESA_03166 NC_009778.1 3081353 3082705 R catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP complement(3081353..3082705) Cronobacter sakazakii ATCC BAA-894 5549505 YP_001439226.1 CDS cdsA NC_009778.1 3082717 3083574 R catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase complement(3082717..3083574) Cronobacter sakazakii ATCC BAA-894 5549619 YP_001439227.1 CDS ESA_03168 NC_009778.1 3083587 3084345 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(3083587..3084345) Cronobacter sakazakii ATCC BAA-894 5549566 YP_001439228.1 CDS ESA_03169 NC_009778.1 3084534 3085763 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(3084534..3085763) Cronobacter sakazakii ATCC BAA-894 5549656 YP_001439229.1 CDS ESA_03170 NC_009778.1 3085855 3086376 R KEGG: fth:FTH_0222 3.8e-45 prfH; protein-synthesizing GTPase; COG: COG0233 Ribosome recycling factor; Psort location: nuclear, score: 23; hypothetical protein complement(3085855..3086376) Cronobacter sakazakii ATCC BAA-894 5550272 YP_001439230.1 CDS pyrH NC_009778.1 3086581 3087306 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(3086581..3087306) Cronobacter sakazakii ATCC BAA-894 5549485 YP_001439231.1 CDS tsf NC_009778.1 3087453 3088304 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(3087453..3088304) Cronobacter sakazakii ATCC BAA-894 5549622 YP_001439232.1 CDS rpsB NC_009778.1 3088461 3089186 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(3088461..3089186) Cronobacter sakazakii ATCC BAA-894 5549500 YP_001439233.1 CDS ESA_03175 NC_009778.1 3089496 3090290 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 3089496..3090290 Cronobacter sakazakii ATCC BAA-894 5549552 YP_001439234.1 CDS ESA_03176 NC_009778.1 3090331 3093009 D catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 3090331..3093009 Cronobacter sakazakii ATCC BAA-894 5549477 YP_001439235.1 CDS dapD NC_009778.1 3093052 3093876 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 3093052..3093876 Cronobacter sakazakii ATCC BAA-894 5549470 YP_001439236.1 CDS ESA_03178 NC_009778.1 3093986 3094375 D COG: NOG09673 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 3093986..3094375 Cronobacter sakazakii ATCC BAA-894 5550042 YP_001439237.1 CDS ESA_03179 NC_009778.1 3094454 3095881 R protease Do; required at high temperature; degrades damaged proteins; serine endoprotease complement(3094454..3095881) Cronobacter sakazakii ATCC BAA-894 5549474 YP_001439238.1 CDS dgt NC_009778.1 3096022 3097536 R forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase complement(3096022..3097536) Cronobacter sakazakii ATCC BAA-894 5550079 YP_001439239.1 CDS ESA_03181 NC_009778.1 3097629 3098327 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 3097629..3098327 Cronobacter sakazakii ATCC BAA-894 5550289 YP_001439240.1 CDS ESA_03182 NC_009778.1 3098320 3099120 D solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 3098320..3099120 Cronobacter sakazakii ATCC BAA-894 5549689 YP_001439241.1 CDS ESA_03183 NC_009778.1 3099137 3099757 D COG: COG2860 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein 3099137..3099757 Cronobacter sakazakii ATCC BAA-894 5550279 YP_001439242.1 CDS ESA_03184 NC_009778.1 3099811 3100155 R COG: COG0316 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3099811..3100155) Cronobacter sakazakii ATCC BAA-894 5550222 YP_001439243.1 CDS ESA_03185 NC_009778.1 3100237 3101640 R Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein complement(3100237..3101640) Cronobacter sakazakii ATCC BAA-894 5549625 YP_001439244.1 CDS ESA_03186 NC_009778.1 3101813 3103093 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 3101813..3103093 Cronobacter sakazakii ATCC BAA-894 5550245 YP_001439245.1 CDS ESA_03187 NC_009778.1 3103304 3105289 R part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit complement(3103304..3105289) Cronobacter sakazakii ATCC BAA-894 5551883 YP_001439246.1 CDS ESA_03188 NC_009778.1 3105286 3106182 R Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit complement(3105286..3106182) Cronobacter sakazakii ATCC BAA-894 5549855 YP_001439247.1 CDS ESA_03189 NC_009778.1 3106182 3107081 R part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit complement(3106182..3107081) Cronobacter sakazakii ATCC BAA-894 5549596 YP_001439248.1 CDS ESA_03190 NC_009778.1 3107027 3109219 R involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter complement(3107027..3109219) Cronobacter sakazakii ATCC BAA-894 5549575 YP_001439249.1 CDS mrcB NC_009778.1 3109494 3112025 R bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b complement(3109494..3112025) Cronobacter sakazakii ATCC BAA-894 5549663 YP_001439250.1 CDS ESA_03192 NC_009778.1 3112129 3114615 R similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB complement(3112129..3114615) Cronobacter sakazakii ATCC BAA-894 5552388 YP_001439251.1 CDS ESA_03193 NC_009778.1 3114630 3115160 D KEGG: stm:STM0188 2.1e-67 ligT; 2'-5' RNA ligase K01975; COG: COG1514 2-5 RNA ligase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3114630..3115160 Cronobacter sakazakii ATCC BAA-894 5549511 YP_001439252.1 CDS ESA_03194 NC_009778.1 3115170 3115874 D Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 3115170..3115874 Cronobacter sakazakii ATCC BAA-894 5550190 YP_001439253.1 CDS dksA NC_009778.1 3116053 3116508 D COG: COG1734 DnaK suppressor protein; Psort location: nuclear, score: 23; RNA polymerase-binding transcription factor 3116053..3116508 Cronobacter sakazakii ATCC BAA-894 5549448 YP_001439254.1 CDS ESA_03196 NC_009778.1 3116578 3117474 D this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 3116578..3117474 Cronobacter sakazakii ATCC BAA-894 5550285 YP_001439255.1 CDS ESA_03197 NC_009778.1 3117563 3118447 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3117563..3118447) Cronobacter sakazakii ATCC BAA-894 5550243 YP_001439256.1 CDS ESA_03198 NC_009778.1 3118454 3118927 D KEGG: eco:b0143 3.4e-67 pcnB; poly(A) polymerase I K00970; COG: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Psort location: nuclear, score: 23; hypothetical protein 3118454..3118927 Cronobacter sakazakii ATCC BAA-894 5549512 YP_001439257.1 CDS ESA_03199 NC_009778.1 3118924 3119403 D KEGG: spt:SPA0189 9.2e-58 folK; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase K00950; COG: COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3118924..3119403 Cronobacter sakazakii ATCC BAA-894 5550268 YP_001439258.1 CDS panB NC_009778.1 3119491 3120285 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 3119491..3120285 Cronobacter sakazakii ATCC BAA-894 5550210 YP_001439259.1 CDS panC NC_009778.1 3120298 3121152 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3120298..3121152 Cronobacter sakazakii ATCC BAA-894 5550209 YP_001439260.1 CDS ESA_03202 NC_009778.1 3121250 3121630 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 3121250..3121630 Cronobacter sakazakii ATCC BAA-894 5550161 YP_001439261.1 CDS ESA_03203 NC_009778.1 3121675 3122922 R KEGG: azo:azo2324 9.7e-22 putative polysaccharide deacetylase; COG: COG0726 Predicted xylanase/chitin deacetylase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3121675..3122922) Cronobacter sakazakii ATCC BAA-894 5549633 YP_001439262.1 CDS ESA_03204 NC_009778.1 3123087 3123857 R COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: plasma membrane, score: 23; hypothetical protein complement(3123087..3123857) Cronobacter sakazakii ATCC BAA-894 5550173 YP_001439263.1 CDS ESA_03205 NC_009778.1 3123854 3124780 R KEGG: pen:PSEEN1596 6.9e-101 ABC transporter, ATP-binding protein; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3123854..3124780) Cronobacter sakazakii ATCC BAA-894 5549532 YP_001439264.1 CDS ESA_03206 NC_009778.1 3124889 3125551 D catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 3124889..3125551 Cronobacter sakazakii ATCC BAA-894 5550214 YP_001439265.1 CDS ESA_03207 NC_009778.1 3125607 3126143 R KEGG: sec:SC0170 1.5e-82 hpt; hypoxanTHIne phosphoribosyltransferase K00760; COG: COG0634 HypoxanTHIne-guanine phosphoribosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3125607..3126143) Cronobacter sakazakii ATCC BAA-894 5552160 YP_001439266.1 CDS ESA_03208 NC_009778.1 3126288 3128732 D KEGG: stm:STM0169 0. gcd; glucose dehydrogenase K00117; COG: COG4993 Glucose dehydrogenase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3126288..3128732 Cronobacter sakazakii ATCC BAA-894 5550256 YP_001439267.1 CDS ESA_03209 NC_009778.1 3129115 3130704 R laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase complement(3129115..3130704) Cronobacter sakazakii ATCC BAA-894 5549624 YP_001439268.1 CDS ESA_03210 NC_009778.1 3131523 3131669 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3131523..3131669) Cronobacter sakazakii ATCC BAA-894 5551249 YP_001439269.1 CDS ESA_03211 NC_009778.1 3131767 3132237 D COG: NOG09835 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3131767..3132237 Cronobacter sakazakii ATCC BAA-894 5551283 YP_001439270.1 CDS ESA_03212 NC_009778.1 3132361 3133212 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 3132361..3133212 Cronobacter sakazakii ATCC BAA-894 5552120 YP_001439271.1 CDS ESA_03213 NC_009778.1 3133227 3134021 D S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 3133227..3134021 Cronobacter sakazakii ATCC BAA-894 5552105 YP_001439272.1 CDS ESA_03214 NC_009778.1 3134050 3134415 R COG: COG3112 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3134050..3134415) Cronobacter sakazakii ATCC BAA-894 5552122 YP_001439273.1 CDS ESA_03215 NC_009778.1 3134599 3134979 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3134599..3134979 Cronobacter sakazakii ATCC BAA-894 5552067 YP_001439274.1 CDS ESA_03216 NC_009778.1 3135065 3137689 R catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase complement(3135065..3137689) Cronobacter sakazakii ATCC BAA-894 5552062 YP_001439275.1 CDS ESA_03217 NC_009778.1 3138569 3140050 D KEGG: aha:AHA_2211 8.8e-05 dnaX; DNA polymerase III, subunits gamma and tau K00961; COG: NOG06276 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3138569..3140050 Cronobacter sakazakii ATCC BAA-894 5552102 YP_001439276.1 CDS ESA_03218 NC_009778.1 3140034 3140858 D COG: NOG09806 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3140034..3140858 Cronobacter sakazakii ATCC BAA-894 5552155 YP_001439277.1 CDS ESA_03219 NC_009778.1 3140914 3141645 R COG: NOG11181 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3140914..3141645) Cronobacter sakazakii ATCC BAA-894 5552060 YP_001439278.1 CDS ESA_03220 NC_009778.1 3141959 3143386 R E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(3141959..3143386) Cronobacter sakazakii ATCC BAA-894 5552086 YP_001439279.1 CDS ESA_03221 NC_009778.1 3143518 3145626 D Psort location: cytoplasmic, score: 23; hypothetical protein 3143518..3145626 Cronobacter sakazakii ATCC BAA-894 5552047 YP_001439280.1 CDS aceF NC_009778.1 3143590 3145488 R E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase complement(3143590..3145488) Cronobacter sakazakii ATCC BAA-894 5552050 YP_001439281.1 CDS aceE NC_009778.1 3145503 3148184 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(3145503..3148184) Cronobacter sakazakii ATCC BAA-894 5551970 YP_001439282.1 CDS pdhR NC_009778.1 3148422 3149186 R activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR complement(3148422..3149186) Cronobacter sakazakii ATCC BAA-894 5551992 YP_001439283.1 CDS ESA_03225 NC_009778.1 3149726 3151099 D KEGG: eci:UTI89_C0120 8.5e-222 aroP; aromatic amino acid transport protein AroP K03293; COG: COG1113 Gamma-aminobutyrate permease and related permeases; Psort location: plasma membrane, score: 23; aromatic amino acid transporter 3149726..3151099 Cronobacter sakazakii ATCC BAA-894 5552358 YP_001439284.1 CDS ESA_03226 NC_009778.1 3151217 3152656 D KEGG: eci:UTI89_C4210 1.9e-112 yicJ; hypothetical symporter YicJ K03292; COG: COG2211 Na+/melibiose symporter and related transporters; Psort location: plasma membrane, score: 23; hypothetical protein 3151217..3152656 Cronobacter sakazakii ATCC BAA-894 5552033 YP_001439285.1 CDS ESA_03227 NC_009778.1 3152663 3153619 D KEGG: sde:Sde_0777 4.0e-105 ribosomal protein L11 methyltransferase K01209; COG: COG3940 Predicted beta-xylosidase; Psort location: cytoplasmic, score: 23; hypothetical protein 3152663..3153619 Cronobacter sakazakii ATCC BAA-894 5551995 YP_001439286.1 CDS ESA_03228 NC_009778.1 3153639 3154493 R involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE complement(3153639..3154493) Cronobacter sakazakii ATCC BAA-894 5551933 YP_001439287.1 CDS ESA_03229 NC_009778.1 3154490 3155053 R KEGG: eci:UTI89_C0118 1.9e-80 ampD; AmpD protein K03806; COG: COG3023 Negative regulator of beta-lactamase expression; Psort location: cytoplasmic, score: 23; N-acetyl-anhydromuranmyl-L-alanine amidase complement(3154490..3155053) Cronobacter sakazakii ATCC BAA-894 5552008 YP_001439288.1 CDS ESA_03230 NC_009778.1 3155141 3156031 D catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 3155141..3156031 Cronobacter sakazakii ATCC BAA-894 5551937 YP_001439289.1 CDS ESA_03231 NC_009778.1 3156284 3156718 D COG: COG4969 Tfp pilus assembly protein, major pilin PilA; Psort location: mitochondrial, score: 23; putative major pilin subunit 3156284..3156718 Cronobacter sakazakii ATCC BAA-894 5551865 YP_001439290.1 CDS ESA_03232 NC_009778.1 3156733 3158115 D KEGG: pen:PSEEN2333 5.6e-83 xcpR-2; type II secretion pathway protein E K01509; COG: COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Psort location: cytoplasmic, score: 23; hypothetical protein 3156733..3158115 Cronobacter sakazakii ATCC BAA-894 5551942 YP_001439291.1 CDS ESA_03233 NC_009778.1 3158108 3159307 D COG: COG1459 Type II secretory pathway, component PulF; Psort location: endoplasmic reticulum, score: 9; type IV pilin biogenesis protein 3158108..3159307 Cronobacter sakazakii ATCC BAA-894 5551940 YP_001439292.1 CDS ESA_03234 NC_009778.1 3159347 3160420 R catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase complement(3159347..3160420) Cronobacter sakazakii ATCC BAA-894 5551903 YP_001439293.1 CDS coaE NC_009778.1 3160655 3161275 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 3160655..3161275 Cronobacter sakazakii ATCC BAA-894 5551947 YP_001439294.1 CDS ESA_03237 NC_009778.1 3161230 3161355 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3161230..3161355) Cronobacter sakazakii ATCC BAA-894 5551926 YP_001439295.1 CDS ESA_03236 NC_009778.1 3161275 3162018 D COG: COG4582 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 3161275..3162018 Cronobacter sakazakii ATCC BAA-894 5551900 YP_001439296.1 CDS ESA_03238 NC_009778.1 3162025 3162228 D KEGG: gbe:GbCGDNIH1_1027 1.3e-05 ribonuclease G; COG: COG3024 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 3162025..3162228 Cronobacter sakazakii ATCC BAA-894 5551924 YP_001439297.1 CDS ESA_03239 NC_009778.1 3162225 3162617 R KEGG: spt:SPA0139 1.8e-52 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase K03574; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: cytoplasmic, score: 23; nucleoside triphosphate pyrophosphohydrolase complement(3162225..3162617) Cronobacter sakazakii ATCC BAA-894 5551909 YP_001439298.1 CDS ESA_03240 NC_009778.1 3162678 3165383 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(3162678..3165383) Cronobacter sakazakii ATCC BAA-894 5550287 YP_001439299.1 CDS ESA_03241 NC_009778.1 3165441 3166016 R secM translational pause allows for the initiation of secA translation; SecA regulator SecM complement(3165441..3166016) Cronobacter sakazakii ATCC BAA-894 5551876 YP_001439300.1 CDS lpxC NC_009778.1 3166222 3167139 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(3166222..3167139) Cronobacter sakazakii ATCC BAA-894 5552204 YP_001439301.1 CDS ESA_03243 NC_009778.1 3167241 3168392 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(3167241..3168392) Cronobacter sakazakii ATCC BAA-894 5551772 YP_001439302.1 CDS ftsA NC_009778.1 3168456 3169712 R ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA complement(3168456..3169712) Cronobacter sakazakii ATCC BAA-894 5551808 YP_001439303.1 CDS ESA_03245 NC_009778.1 3169709 3170539 R involved in septum formation; cell division protein FtsQ complement(3169709..3170539) Cronobacter sakazakii ATCC BAA-894 5551881 YP_001439304.1 CDS ddl NC_009778.1 3170541 3171461 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase complement(3170541..3171461) Cronobacter sakazakii ATCC BAA-894 5551844 YP_001439305.1 CDS murC NC_009778.1 3171454 3172920 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(3171454..3172920) Cronobacter sakazakii ATCC BAA-894 5551784 YP_001439306.1 CDS murG NC_009778.1 3172988 3174055 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase complement(3172988..3174055) Cronobacter sakazakii ATCC BAA-894 5551862 YP_001439307.1 CDS ESA_03249 NC_009778.1 3174052 3175251 R integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW complement(3174052..3175251) Cronobacter sakazakii ATCC BAA-894 5551853 YP_001439308.1 CDS murD NC_009778.1 3175296 3176612 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(3175296..3176612) Cronobacter sakazakii ATCC BAA-894 5551783 YP_001439309.1 CDS mraY NC_009778.1 3176615 3177697 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(3176615..3177697) Cronobacter sakazakii ATCC BAA-894 5551738 YP_001439310.1 CDS murF NC_009778.1 3177691 3179049 R KEGG: sbo:SBO_0074 6.7e-206 murF; D-alanine:D-alanine-adding enzyme K01929; COG: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; Psort location: cytoplasmic, score: 23; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(3177691..3179049) Cronobacter sakazakii ATCC BAA-894 5551801 YP_001439311.1 CDS murE NC_009778.1 3179046 3180461 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(3179046..3180461) Cronobacter sakazakii ATCC BAA-894 5551758 YP_001439312.1 CDS ESA_03254 NC_009778.1 3180520 3182286 R KEGG: eco:b0084 3.0e-297 ftsI, pbpB, sep; division-specific transpeptidase, penicillin-binding protein 3 K03587; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: golgi, score: 9; hypothetical protein complement(3180520..3182286) Cronobacter sakazakii ATCC BAA-894 5551797 YP_001439313.1 CDS ESA_03255 NC_009778.1 3182302 3182667 R membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL complement(3182302..3182667) Cronobacter sakazakii ATCC BAA-894 5551769 YP_001439314.1 CDS mraW NC_009778.1 3182664 3183605 R KEGG: spt:SPA0122 3.5e-152 yabC; putative S-adenosyl meTHIonine adenyltransferase K03438; COG: COG0275 Predicted S-adenosylmeTHIonine-dependent methyltransferase involved in cell envelope biogenesis; Psort location: cytoplasmic, score: 23; S-adenosyl-methyltransferase MraW complement(3182664..3183605) Cronobacter sakazakii ATCC BAA-894 5551723 YP_001439315.1 CDS ESA_03257 NC_009778.1 3183609 3184067 R MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ complement(3183609..3184067) Cronobacter sakazakii ATCC BAA-894 5551752 YP_001439316.1 CDS ESA_03258 NC_009778.1 3184647 3185651 R binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR complement(3184647..3185651) Cronobacter sakazakii ATCC BAA-894 5551749 YP_001439317.1 CDS ESA_03259 NC_009778.1 3185695 3185826 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3185695..3185826) Cronobacter sakazakii ATCC BAA-894 5551662 YP_001439318.1 CDS ilvH NC_009778.1 3185829 3186320 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(3185829..3186320) Cronobacter sakazakii ATCC BAA-894 5551753 YP_001439319.1 CDS ESA_03261 NC_009778.1 3186323 3188047 R catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit complement(3186323..3188047) Cronobacter sakazakii ATCC BAA-894 5551651 YP_001439320.1 CDS ESA_03262 NC_009778.1 3188186 3188386 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3188186..3188386) Cronobacter sakazakii ATCC BAA-894 5551733 YP_001439321.1 CDS leuO NC_009778.1 3188447 3189391 R activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator complement(3188447..3189391) Cronobacter sakazakii ATCC BAA-894 5551672 YP_001439322.1 CDS ESA_03264 NC_009778.1 3190192 3191763 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 3190192..3191763 Cronobacter sakazakii ATCC BAA-894 5552198 YP_001439323.1 CDS ESA_03265 NC_009778.1 3191763 3192854 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 3191763..3192854 Cronobacter sakazakii ATCC BAA-894 5551616 YP_001439324.1 CDS ESA_03266 NC_009778.1 3192857 3194257 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 3192857..3194257 Cronobacter sakazakii ATCC BAA-894 5551658 YP_001439325.1 CDS leuD NC_009778.1 3194268 3194873 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 3194268..3194873 Cronobacter sakazakii ATCC BAA-894 5551642 YP_001439326.1 CDS ESA_03268 NC_009778.1 3195045 3196232 R COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(3195045..3196232) Cronobacter sakazakii ATCC BAA-894 5551628 YP_001439327.1 CDS ESA_03269 NC_009778.1 3196343 3196525 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3196343..3196525) Cronobacter sakazakii ATCC BAA-894 5551577 YP_001439328.1 CDS ESA_03270 NC_009778.1 3196594 3198258 D activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 3196594..3198258 Cronobacter sakazakii ATCC BAA-894 5551618 YP_001439329.1 CDS tbpA NC_009778.1 3198428 3199411 D part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 3198428..3199411 Cronobacter sakazakii ATCC BAA-894 5551572 YP_001439330.1 CDS thiP NC_009778.1 3199387 3200997 D permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 3199387..3200997 Cronobacter sakazakii ATCC BAA-894 5551583 YP_001439331.1 CDS thiQ NC_009778.1 3200981 3201682 D with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 3200981..3201682 Cronobacter sakazakii ATCC BAA-894 5551565 YP_001439332.1 CDS ESA_03274 NC_009778.1 3201676 3202446 R KEGG: lsl:LSL_1322 0.0039 alkaline phosphatase K01077; COG: COG0586 Uncharacterized membrane-associated protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3201676..3202446) Cronobacter sakazakii ATCC BAA-894 5551576 YP_001439333.1 CDS ESA_03275 NC_009778.1 3202563 3203408 R positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC complement(3202563..3203408) Cronobacter sakazakii ATCC BAA-894 5551567 YP_001439334.1 CDS ESA_03276 NC_009778.1 3203742 3205460 D catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 3203742..3205460 Cronobacter sakazakii ATCC BAA-894 5551481 YP_001439335.1 CDS ESA_03277 NC_009778.1 3205468 3206973 D catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 3205468..3206973 Cronobacter sakazakii ATCC BAA-894 5551497 YP_001439336.1 CDS araD NC_009778.1 3207059 3207754 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3207059..3207754 Cronobacter sakazakii ATCC BAA-894 5551515 YP_001439337.1 CDS ESA_03279 NC_009778.1 3207062 3207802 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3207062..3207802) Cronobacter sakazakii ATCC BAA-894 5551543 YP_001439338.1 CDS ESA_03280 NC_009778.1 3207888 3210248 D Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 3207888..3210248 Cronobacter sakazakii ATCC BAA-894 5551536 YP_001439339.1 CDS ESA_03281 NC_009778.1 3210382 3213288 D transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 3210382..3213288 Cronobacter sakazakii ATCC BAA-894 5551528 YP_001439340.1 CDS ESA_03282 NC_009778.1 3213301 3213957 D catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 3213301..3213957 Cronobacter sakazakii ATCC BAA-894 5551494 YP_001439341.1 CDS djlA NC_009778.1 3214041 3214853 R functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein complement(3214041..3214853) Cronobacter sakazakii ATCC BAA-894 5551471 YP_001439342.1 CDS ESA_03284 NC_009778.1 3215037 3217400 D determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 3215037..3217400 Cronobacter sakazakii ATCC BAA-894 5551461 YP_001439343.1 CDS ESA_03285 NC_009778.1 3217454 3218740 D Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 3217454..3218740 Cronobacter sakazakii ATCC BAA-894 5551517 YP_001439344.1 CDS ksgA NC_009778.1 3219731 3220552 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 3219731..3220552 Cronobacter sakazakii ATCC BAA-894 5551489 YP_001439345.1 CDS apaG NC_009778.1 3220555 3220932 D protein associated with Co2+ and Mg2+ efflux; ApaG 3220555..3220932 Cronobacter sakazakii ATCC BAA-894 5551476 YP_001439346.1 CDS apaH NC_009778.1 3220937 3221788 D hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 3220937..3221788 Cronobacter sakazakii ATCC BAA-894 5551482 YP_001439347.1 CDS folA NC_009778.1 3222055 3222534 R catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase complement(3222055..3222534) Cronobacter sakazakii ATCC BAA-894 5551464 YP_001439348.1 CDS ESA_03291 NC_009778.1 3222637 3222771 D Psort location: mitochondrial, score: 23; hypothetical protein 3222637..3222771 Cronobacter sakazakii ATCC BAA-894 5552373 YP_001439349.1 CDS ESA_03292 NC_009778.1 3222800 3223414 D COG: COG1280 Putative threonine efflux protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3222800..3223414 Cronobacter sakazakii ATCC BAA-894 5551451 YP_001439350.1 CDS ESA_03293 NC_009778.1 3223465 3225327 R transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC complement(3223465..3225327) Cronobacter sakazakii ATCC BAA-894 5551454 YP_001439351.1 CDS ESA_03294 NC_009778.1 3225320 3225793 R Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF complement(3225320..3225793) Cronobacter sakazakii ATCC BAA-894 5551433 YP_001439352.1 CDS ESA_03295 NC_009778.1 3226064 3226297 R COG: NOG17119 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3226064..3226297) Cronobacter sakazakii ATCC BAA-894 5552018 YP_001439353.1 CDS ESA_03296 NC_009778.1 3226430 3227329 R Psort location: nuclear, score: 23; hypothetical protein complement(3226430..3227329) Cronobacter sakazakii ATCC BAA-894 5551436 YP_001439354.1 CDS carB NC_009778.1 3227453 3230677 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(3227453..3230677) Cronobacter sakazakii ATCC BAA-894 5551410 YP_001439355.1 CDS ESA_03298 NC_009778.1 3230695 3231870 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(3230695..3231870) Cronobacter sakazakii ATCC BAA-894 5551368 YP_001439356.1 CDS ESA_03299 NC_009778.1 3231876 3232010 D Psort location: cytoplasmic, score: 23; hypothetical protein 3231876..3232010 Cronobacter sakazakii ATCC BAA-894 5551441 YP_001439357.1 CDS ESA_03300 NC_009778.1 3232311 3233132 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(3232311..3233132) Cronobacter sakazakii ATCC BAA-894 5551369 YP_001439358.1 CDS ESA_03301 NC_009778.1 3233494 3234237 D KEGG: pto:PTO0012 0.0096 isomerizing glucosamine--fructose-6-phosphate aminotransferase K00820; COG: COG1737 Transcriptional regulators; Psort location: mitochondrial, score: 23; hypothetical protein 3233494..3234237 Cronobacter sakazakii ATCC BAA-894 5551359 YP_001439359.1 CDS ESA_03302 NC_009778.1 3234250 3234993 R COG: NOG06222 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3234250..3234993) Cronobacter sakazakii ATCC BAA-894 5551365 YP_001439360.1 CDS ESA_03303 NC_009778.1 3235402 3237360 D KEGG: lmo:lmo2733 4.7e-205 similar to PTS system, fructose-specific IIABC component K02768:K02769:K02770; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: plasma membrane, score: 23; hypothetical protein 3235402..3237360 Cronobacter sakazakii ATCC BAA-894 5551352 YP_001439361.1 CDS ESA_03304 NC_009778.1 3237378 3240041 D KEGG: lmf:LMOf2365_0421 3.6e-104 glycosyl hydrolase, family 38 K01191; COG: COG0383 Alpha-mannosidase; Psort location: cytoplasmic, score: 23; hypothetical protein 3237378..3240041 Cronobacter sakazakii ATCC BAA-894 5551339 YP_001439362.1 CDS ESA_03305 NC_009778.1 3240034 3241782 D KEGG: sth:STH1983 3.0e-24 mannnose-6 phospate isomerase K01809; COG: COG1482 Phosphomannose isomerase; Psort location: cytoplasmic, score: 23; hypothetical protein 3240034..3241782 Cronobacter sakazakii ATCC BAA-894 5551342 YP_001439363.1 CDS ESA_03306 NC_009778.1 3241899 3242531 R KEGG: rru:Rru_A2969 3.3e-14 alanyl-tRNA synthetase related protein K01872; COG: COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3241899..3242531) Cronobacter sakazakii ATCC BAA-894 5551319 YP_001439364.1 CDS ESA_03307 NC_009778.1 3242626 3243522 D KEGG: shn:Shewana3_3435 9.3e-07 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 3242626..3243522 Cronobacter sakazakii ATCC BAA-894 5551864 YP_001439365.1 CDS ESA_03308 NC_009778.1 3243519 3244436 R catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC complement(3243519..3244436) Cronobacter sakazakii ATCC BAA-894 5551312 YP_001439366.1 CDS ispH NC_009778.1 3244530 3245480 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(3244530..3245480) Cronobacter sakazakii ATCC BAA-894 5551308 YP_001439367.1 CDS ESA_03310 NC_009778.1 3245461 3245931 R KEGG: sec:SC0042 4.1e-64 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03774; COG: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3245461..3245931) Cronobacter sakazakii ATCC BAA-894 5551284 YP_001439368.1 CDS lspA NC_009778.1 3246035 3246532 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(3246035..3246532) Cronobacter sakazakii ATCC BAA-894 5551290 YP_001439369.1 CDS ileS NC_009778.1 3246532 3249348 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(3246532..3249348) Cronobacter sakazakii ATCC BAA-894 5551289 YP_001439370.1 CDS ESA_03313 NC_009778.1 3249397 3250335 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(3249397..3250335) Cronobacter sakazakii ATCC BAA-894 5551275 YP_001439371.1 CDS ESA_03314 NC_009778.1 3250731 3250916 D COG: COG0268 Ribosomal protein S20; Psort location: nuclear, score: 23; hypothetical protein 3250731..3250916 Cronobacter sakazakii ATCC BAA-894 5551293 YP_001439372.1 CDS nhaR NC_009778.1 3250993 3251889 R Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR complement(3250993..3251889) Cronobacter sakazakii ATCC BAA-894 5552493 YP_001439373.1 CDS nhaA NC_009778.1 3251961 3253133 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(3251961..3253133) Cronobacter sakazakii ATCC BAA-894 5551273 YP_001439374.1 CDS ESA_03317 NC_009778.1 3253368 3255455 R KEGG: vfi:VF1598 1.1e-46 exochitinase K01183; COG: COG3325 Chitinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3253368..3255455) Cronobacter sakazakii ATCC BAA-894 5551523 YP_001439375.1 CDS ESA_03318 NC_009778.1 3255458 3255601 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3255458..3255601) Cronobacter sakazakii ATCC BAA-894 5551251 YP_001439376.1 CDS ESA_03319 NC_009778.1 3255858 3256304 D COG: COG3710 DNA-binding winged-HTH domains; Psort location: vesicles of secretory system, score: 9; hypothetical protein 3255858..3256304 Cronobacter sakazakii ATCC BAA-894 5551222 YP_001439377.1 CDS ESA_03320 NC_009778.1 3256326 3256865 D COG: COG3926 Putative secretion activating protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3256326..3256865 Cronobacter sakazakii ATCC BAA-894 5551256 YP_001439378.1 CDS ESA_03321 NC_009778.1 3256913 3257251 R COG: NOG17566 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3256913..3257251) Cronobacter sakazakii ATCC BAA-894 5551231 YP_001439379.1 CDS ESA_03322 NC_009778.1 3257435 3258382 R COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3257435..3258382) Cronobacter sakazakii ATCC BAA-894 5551247 YP_001439380.1 CDS ESA_03323 NC_009778.1 3258450 3258629 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3258450..3258629) Cronobacter sakazakii ATCC BAA-894 5551257 YP_001439381.1 CDS ESA_03324 NC_009778.1 3258654 3259793 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(3258654..3259793) Cronobacter sakazakii ATCC BAA-894 5551242 YP_001439382.1 CDS ESA_03325 NC_009778.1 3259812 3261908 D COG: NOG10237 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3259812..3261908 Cronobacter sakazakii ATCC BAA-894 5551245 YP_001439383.1 CDS dnaK NC_009778.1 3259878 3261794 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(3259878..3261794) Cronobacter sakazakii ATCC BAA-894 5551246 YP_001439384.1 CDS ESA_03327 NC_009778.1 3262086 3262652 D COG: COG1584 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3262086..3262652 Cronobacter sakazakii ATCC BAA-894 5551234 YP_001439385.1 CDS ESA_03328 NC_009778.1 3262710 3264011 R COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(3262710..3264011) Cronobacter sakazakii ATCC BAA-894 5551201 YP_001439386.1 CDS mogA NC_009778.1 3264139 3264726 R forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA complement(3264139..3264726) Cronobacter sakazakii ATCC BAA-894 5551237 YP_001439387.1 CDS ESA_03330 NC_009778.1 3264835 3265788 R KEGG: stt:t0007 3.3e-156 talB; transaldolase B K00616; COG: COG0176 Transaldolase; Psort location: cytoplasmic, score: 23; transaldolase B complement(3264835..3265788) Cronobacter sakazakii ATCC BAA-894 5551215 YP_001439388.1 CDS ESA_03331 NC_009778.1 3265994 3267418 D KEGG: hpa:HPAG1_0925 2.3e-52 D-alanine glycine permease K01613; COG: COG1115 Na+/alanine symporter; Psort location: plasma membrane, score: 23; hypothetical protein 3265994..3267418 Cronobacter sakazakii ATCC BAA-894 5551218 YP_001439389.1 CDS ESA_03332 NC_009778.1 3267497 3268270 D COG: COG3022 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 3267497..3268270 Cronobacter sakazakii ATCC BAA-894 5551197 YP_001439390.1 CDS ESA_03333 NC_009778.1 3268322 3269611 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(3268322..3269611) Cronobacter sakazakii ATCC BAA-894 5551217 YP_001439391.1 CDS ESA_03334 NC_009778.1 3269615 3270544 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(3269615..3270544) Cronobacter sakazakii ATCC BAA-894 5551232 YP_001439392.1 CDS thrA NC_009778.1 3270546 3273008 R multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I complement(3270546..3273008) Cronobacter sakazakii ATCC BAA-894 5551211 YP_001439393.1 CDS ESA_03336 NC_009778.1 3273370 3274056 R member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase complement(3273370..3274056) Cronobacter sakazakii ATCC BAA-894 5551203 YP_001439394.1 CDS ESA_03337 NC_009778.1 3274690 3275406 D KEGG: eci:UTI89_C5174 6.4e-121 arcA; ArcA transcriptional dual regulator K07773; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: cytoplasmic, score: 23; two-component response regulator 3274690..3275406 Cronobacter sakazakii ATCC BAA-894 5552420 YP_001439395.1 CDS ESA_03338 NC_009778.1 3275465 3276823 R COG: COG4452 Inner membrane protein involved in colicin E2 resistance; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(3275465..3276823) Cronobacter sakazakii ATCC BAA-894 5551097 YP_001439396.1 CDS ESA_03339 NC_009778.1 3276903 3278327 R part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC complement(3276903..3278327) Cronobacter sakazakii ATCC BAA-894 5551186 YP_001439397.1 CDS ESA_03340 NC_009778.1 3278327 3279019 R response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB complement(3278327..3279019) Cronobacter sakazakii ATCC BAA-894 5551135 YP_001439398.1 CDS ESA_03341 NC_009778.1 3279038 3279532 R COG: COG3045 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3279038..3279532) Cronobacter sakazakii ATCC BAA-894 5551123 YP_001439399.1 CDS ESA_03342 NC_009778.1 3279728 3280597 D KEGG: bat:BAS3585 2.0e-09 Ada regulatory protein/6-O-methylguanine-DNA methyltransferase K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 3279728..3280597 Cronobacter sakazakii ATCC BAA-894 5551141 YP_001439400.1 CDS ESA_03343 NC_009778.1 3280594 3281241 R catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase complement(3280594..3281241) Cronobacter sakazakii ATCC BAA-894 5551182 YP_001439401.1 CDS ESA_03344 NC_009778.1 3281298 3281813 D pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 3281298..3281813 Cronobacter sakazakii ATCC BAA-894 5549227 YP_001439402.1 CDS ESA_03345 NC_009778.1 3281804 3282133 R When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor complement(3281804..3282133) Cronobacter sakazakii ATCC BAA-894 5551139 YP_001439403.1 CDS ESA_03346 NC_009778.1 3282188 3284122 R catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase complement(3282188..3284122) Cronobacter sakazakii ATCC BAA-894 5549232 YP_001439404.1 CDS ESA_03348 NC_009778.1 3284333 3286033 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3284333..3286033) Cronobacter sakazakii ATCC BAA-894 5551085 YP_001439405.1 CDS ESA_03347 NC_009778.1 3284378 3286024 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 3284378..3286024 Cronobacter sakazakii ATCC BAA-894 5551114 YP_001439406.1 CDS ESA_03349 NC_009778.1 3286549 3287664 D KEGG: bpm:BURPS1710b_A1960 2.9e-08 putative transport-related membrane protein K00903; COG: COG3524 Capsule polysaccharide export protein; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 3286549..3287664 Cronobacter sakazakii ATCC BAA-894 5551128 YP_001439407.1 CDS ESA_03351 NC_009778.1 3287581 3287763 R Psort location: nuclear, score: 23; hypothetical protein complement(3287581..3287763) Cronobacter sakazakii ATCC BAA-894 5551156 YP_001439408.1 CDS ESA_03350 NC_009778.1 3287693 3289357 D COG: COG1596 Periplasmic protein involved in polysaccharide export; Psort location: extracellular, including cell wall, score: 23; hypothetical protein 3287693..3289357 Cronobacter sakazakii ATCC BAA-894 5551104 YP_001439409.1 CDS ESA_03352 NC_009778.1 3289362 3291398 D COG: COG3563 Capsule polysaccharide export protein; Psort location: mitochondrial, score: 23; hypothetical protein 3289362..3291398 Cronobacter sakazakii ATCC BAA-894 5551132 YP_001439410.1 CDS ESA_03353 NC_009778.1 3291395 3292600 D COG: COG3562 Capsule polysaccharide export protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3291395..3292600 Cronobacter sakazakii ATCC BAA-894 5551094 YP_001439411.1 CDS ESA_03354 NC_009778.1 3292595 3293824 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3292595..3293824) Cronobacter sakazakii ATCC BAA-894 5552042 YP_001439412.1 CDS ESA_03355 NC_009778.1 3293890 3296757 R KEGG: lsa:LSA1576 1.1e-05 tagB; CDP-glycerol:glycerophosphate glycerophosphotransferase (teichoic acid biosynthesis protein B); COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3293890..3296757) Cronobacter sakazakii ATCC BAA-894 5549218 YP_001439413.1 CDS ESA_03356 NC_009778.1 3296851 3297672 R KEGG: btk:BT9727_5106 4.0e-18 beta-1,3-N-acetylglucosaminyltransferase K00754; COG: COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3296851..3297672) Cronobacter sakazakii ATCC BAA-894 5552217 YP_001439414.1 CDS ESA_03357 NC_009778.1 3297665 3298777 R KEGG: mtu:Rv0806c 1.7e-40 cpsY; possible UDP-glucose-4-epimerase CpsY (galactowaldenase) (UDP-galactose-4-epimerase) (uridine diphosphate galactose-4-epimerase) (uridine diphospho-galactose-4-epimerase) K01784; COG: NOG08826 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3297665..3298777) Cronobacter sakazakii ATCC BAA-894 5549231 YP_001439415.1 CDS ESA_03358 NC_009778.1 3298780 3299445 R KEGG: ecc:c3697 5.6e-90 kpsT; kpsT protein K01990; COG: COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3298780..3299445) Cronobacter sakazakii ATCC BAA-894 5551103 YP_001439416.1 CDS ESA_03359 NC_009778.1 3299442 3300218 R COG: COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3299442..3300218) Cronobacter sakazakii ATCC BAA-894 5551067 YP_001439417.1 CDS ESA_03360 NC_009778.1 3300550 3301467 R KEGG: shn:Shewana3_3435 2.2e-06 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: extracellular, including cell wall, score: 23; hypothetical protein complement(3300550..3301467) Cronobacter sakazakii ATCC BAA-894 5551110 YP_001439418.1 CDS ESA_03361 NC_009778.1 3301583 3302584 D KEGG: bur:Bcep18194_A5075 1.1e-84 zinc-containing alcohol dehydrogenase superfamily K00344; COG: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Psort location: cytoplasmic, score: 23; hypothetical protein 3301583..3302584 Cronobacter sakazakii ATCC BAA-894 5551091 YP_001439419.1 CDS ESA_03362 NC_009778.1 3302893 3304125 R catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase complement(3302893..3304125) Cronobacter sakazakii ATCC BAA-894 5551078 YP_001439420.1 CDS ESA_03363 NC_009778.1 3304211 3305485 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(3304211..3305485) Cronobacter sakazakii ATCC BAA-894 5551086 YP_001439421.1 CDS serB NC_009778.1 3305605 3306489 R catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase complement(3305605..3306489) Cronobacter sakazakii ATCC BAA-894 5551058 YP_001439422.1 CDS ESA_03365 NC_009778.1 3306683 3307345 D KEGG: ece:Z5988 1.8e-86 putative lipoate-protein ligase A K03800:K07186; COG: COG3726 Uncharacterized membrane protein affecting hemolysin expression; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 3306683..3307345 Cronobacter sakazakii ATCC BAA-894 5551049 YP_001439423.1 CDS lplA NC_009778.1 3307394 3308410 D Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 3307394..3308410 Cronobacter sakazakii ATCC BAA-894 5551036 YP_001439424.1 CDS ESA_03367 NC_009778.1 3308585 3309304 R KEGG: sty:STY4921 2.4e-121 deoD, pup; purine nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3308585..3309304) Cronobacter sakazakii ATCC BAA-894 5551073 YP_001439425.1 CDS ESA_03368 NC_009778.1 3309378 3310601 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(3309378..3310601) Cronobacter sakazakii ATCC BAA-894 5551040 YP_001439426.1 CDS deoA NC_009778.1 3310654 3311976 R Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase complement(3310654..3311976) Cronobacter sakazakii ATCC BAA-894 5551045 YP_001439427.1 CDS ESA_03370 NC_009778.1 3312080 3312859 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(3312080..3312859) Cronobacter sakazakii ATCC BAA-894 5551022 YP_001439428.1 CDS ESA_03371 NC_009778.1 3313197 3314474 R COG: COG1972 Nucleoside permease; Psort location: plasma membrane, score: 23; hypothetical protein complement(3313197..3314474) Cronobacter sakazakii ATCC BAA-894 5551044 YP_001439429.1 CDS ESA_03372 NC_009778.1 3314598 3315383 R KEGG: stm:STM4564 3.6e-95 yjjV; putative hydrolase K03424; COG: COG0084 Mg-dependent DNase; Psort location: mitochondrial, score: 23; hypothetical protein complement(3314598..3315383) Cronobacter sakazakii ATCC BAA-894 5551055 YP_001439430.1 CDS ESA_03373 NC_009778.1 3315380 3316513 R KEGG: vfi:VFA0008 8.6e-39 phospholipase; COG: COG4667 Predicted esterase of the alpha-beta hydrolase superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3315380..3316513) Cronobacter sakazakii ATCC BAA-894 5551039 YP_001439431.1 CDS ESA_03374 NC_009778.1 3316443 3316577 R Psort location: nuclear, score: 23; hypothetical protein complement(3316443..3316577) Cronobacter sakazakii ATCC BAA-894 5551020 YP_001439432.1 CDS ESA_03375 NC_009778.1 3316629 3316808 R COG: NOG16919 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 23; hypothetical protein complement(3316629..3316808) Cronobacter sakazakii ATCC BAA-894 5552154 YP_001439433.1 CDS ESA_03376 NC_009778.1 3316918 3317532 R KEGG: yps:YPTB3710 0.0057 fkpA; peptidyl-prolyl cis-trans isomerase K03772; COG: COG2823 Predicted periplasmic or secreted lipoprotein; Psort location: extracellular, including cell wall, score: 9; periplasmic protein complement(3316918..3317532) Cronobacter sakazakii ATCC BAA-894 5551035 YP_001439434.1 CDS prfC NC_009778.1 3317939 3319528 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(3317939..3319528) Cronobacter sakazakii ATCC BAA-894 5550999 YP_001439435.1 CDS ESA_03378 NC_009778.1 3319620 3320297 R manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase complement(3319620..3320297) Cronobacter sakazakii ATCC BAA-894 5551025 YP_001439436.1 CDS rimI NC_009778.1 3320318 3320755 R alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase complement(3320318..3320755) Cronobacter sakazakii ATCC BAA-894 5550991 YP_001439437.1 CDS ESA_03380 NC_009778.1 3320730 3321140 R KEGG: stm:STM4557 6.5e-41 holD; DNA polymerase III, psi subunit K02344; COG: COG3050 DNA polymerase III, psi subunit; Psort location: mitochondrial, score: 23; hypothetical protein complement(3320730..3321140) Cronobacter sakazakii ATCC BAA-894 5550998 YP_001439438.1 CDS rsmC NC_009778.1 3321246 3322274 D 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 3321246..3322274 Cronobacter sakazakii ATCC BAA-894 5550963 YP_001439439.1 CDS ESA_03385 NC_009778.1 3322804 3323085 R COG: NOG09784 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3322804..3323085) Cronobacter sakazakii ATCC BAA-894 5550884 YP_001439440.1 CDS ESA_03386 NC_009778.1 3323282 3324349 D KEGG: ava:Ava_3170 7.3e-26 putative diguanylate cyclase (GGDEF domain) K02488; COG: COG2199 FOG: GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3323282..3324349 Cronobacter sakazakii ATCC BAA-894 5550966 YP_001439441.1 CDS ESA_03387 NC_009778.1 3324542 3325252 D KEGG: gbe:GbCGDNIH1_2380 0.0074 ferric hydroxamate reductase FhuF K00521; COG: COG4114 Uncharacterized Fe-S protein; Psort location: vesicles of secretory system, score: 9; ferric iron reductase involved in ferric hydroximate transport 3324542..3325252 Cronobacter sakazakii ATCC BAA-894 5550931 YP_001439442.1 CDS ESA_03388 NC_009778.1 3325282 3326628 R KEGG: eca:ECA2488 5.8e-120 PTS system, cellobiose-specific IIc component K02761; COG: COG1455 Phosphotransferase system cellobiose-specific component IIC; Psort location: plasma membrane, score: 23; hypothetical protein complement(3325282..3326628) Cronobacter sakazakii ATCC BAA-894 5550938 YP_001439443.1 CDS ESA_03389 NC_009778.1 3327024 3327482 D KEGG: dvu:DVU1345 4.4e-07 proS, pro; prolyl-tRNA synthetase K01881; COG: COG2606 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3327024..3327482 Cronobacter sakazakii ATCC BAA-894 5550982 YP_001439444.1 CDS ESA_03390 NC_009778.1 3327519 3328121 R regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ complement(3327519..3328121) Cronobacter sakazakii ATCC BAA-894 5550971 YP_001439445.1 CDS ESA_03391 NC_009778.1 3328136 3328801 R COG: NOG09075 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(3328136..3328801) Cronobacter sakazakii ATCC BAA-894 5550957 YP_001439446.1 CDS ESA_03392 NC_009778.1 3329367 3330143 D COG: COG2966 Uncharacterized conserved protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3329367..3330143 Cronobacter sakazakii ATCC BAA-894 5550953 YP_001439447.1 CDS ESA_03393 NC_009778.1 3330119 3330607 D COG: COG3610 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3330119..3330607 Cronobacter sakazakii ATCC BAA-894 5550947 YP_001439448.1 CDS ESA_03394 NC_009778.1 3330673 3331128 D COG: COG1846 Transcriptional regulators; Psort location: nuclear, score: 23; hypothetical protein 3330673..3331128 Cronobacter sakazakii ATCC BAA-894 5550911 YP_001439449.1 CDS ESA_03395 NC_009778.1 3331209 3331637 D KEGG: reh:H16_A1791 3.7e-31 predicted redox protein, regulator of disulfide bond formation K01768; COG: COG1764 Predicted redox protein, regulator of disulfide bond formation; Psort location: cytoplasmic, score: 23; hypothetical protein 3331209..3331637 Cronobacter sakazakii ATCC BAA-894 5550907 YP_001439450.1 CDS ESA_03396 NC_009778.1 3331860 3332405 D This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 3331860..3332405 Cronobacter sakazakii ATCC BAA-894 5552315 YP_001439451.1 CDS ESA_03397 NC_009778.1 3332408 3333145 D acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 3332408..3333145 Cronobacter sakazakii ATCC BAA-894 5550926 YP_001439452.1 CDS ESA_03398 NC_009778.1 3333507 3335804 D catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 3333507..3335804 Cronobacter sakazakii ATCC BAA-894 5550915 YP_001439453.1 CDS ESA_03399 NC_009778.1 3335814 3336773 R KEGG: lpn:lpg1490 6.4e-34 cyaA; adenylate cyclase PLUS two component hybrid sensor and regulator K01768; COG: COG2199 FOG: GGDEF domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3335814..3336773) Cronobacter sakazakii ATCC BAA-894 5550906 YP_001439454.1 CDS ESA_03400 NC_009778.1 3336751 3336897 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3336751..3336897) Cronobacter sakazakii ATCC BAA-894 5552001 YP_001439455.1 CDS ESA_03401 NC_009778.1 3336947 3338719 R KEGG: syn:sll1687 1.1e-48 hik17; hypothetical protein; COG: COG2203 FOG: GAF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3336947..3338719) Cronobacter sakazakii ATCC BAA-894 5550902 YP_001439456.1 CDS ESA_03402 NC_009778.1 3338974 3340641 R KEGG: syn:sll1871 3.0e-06 hik6; two-component sensor histidine kinase K02486; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3338974..3340641) Cronobacter sakazakii ATCC BAA-894 5550895 YP_001439457.1 CDS ESA_03403 NC_009778.1 3340937 3342136 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3340937..3342136) Cronobacter sakazakii ATCC BAA-894 5549017 YP_001439458.1 CDS ESA_03404 NC_009778.1 3342301 3345348 R KEGG: pen:PSEEN3027 0. serine protease PspB; COG: COG1404 Subtilisin-like serine proteases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3342301..3345348) Cronobacter sakazakii ATCC BAA-894 5550876 YP_001439459.1 CDS ESA_03405 NC_009778.1 3346016 3347251 R KEGG: bam:Bamb_3745 2.5e-183 N-isopropylammelide isopropylaminohydrolase K08710; COG: COG0402 Cytosine deaminase and related metal-dependent hydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3346016..3347251) Cronobacter sakazakii ATCC BAA-894 5550883 YP_001439460.1 CDS codB NC_009778.1 3347285 3348553 R COG: COG1457 Purine-cytosine permease and related proteins; Psort location: plasma membrane, score: 23; cytosine permease complement(3347285..3348553) Cronobacter sakazakii ATCC BAA-894 5550869 YP_001439461.1 CDS ESA_03407 NC_009778.1 3348778 3350208 R KEGG: eci:UTI89_C3078 2.0e-229 ascB; 6-phospho-beta-glucosidase K01223; COG: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Psort location: cytoplasmic, score: 23; cryptic 6-phospho-beta-glucosidase complement(3348778..3350208) Cronobacter sakazakii ATCC BAA-894 5550879 YP_001439462.1 CDS ESA_03408 NC_009778.1 3350222 3351709 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC complement(3350222..3351709) Cronobacter sakazakii ATCC BAA-894 5549815 YP_001439463.1 CDS ESA_03409 NC_009778.1 3352005 3353018 D KEGG: efa:EF1922 3.3e-12 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 3352005..3353018 Cronobacter sakazakii ATCC BAA-894 5550852 YP_001439464.1 CDS ESA_03410 NC_009778.1 3353000 3353401 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3353000..3353401) Cronobacter sakazakii ATCC BAA-894 5550857 YP_001439465.1 CDS ESA_03411 NC_009778.1 3353509 3354579 R COG: NOG06307 non supervised orthologous group; Psort location: plasma membrane, score: 23; hypothetical protein complement(3353509..3354579) Cronobacter sakazakii ATCC BAA-894 5549836 YP_001439466.1 CDS ESA_03412 NC_009778.1 3354582 3355649 R COG: COG1566 Multidrug resistance efflux pump; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3354582..3355649) Cronobacter sakazakii ATCC BAA-894 5549799 YP_001439467.1 CDS ESA_03413 NC_009778.1 3355652 3356122 R KEGG: dra:DR0030 0.0098 2-oxoisovalerate dehydrogenase beta subunit K00167; COG: COG1846 Transcriptional regulators; Psort location: nuclear, score: 23; hypothetical protein complement(3355652..3356122) Cronobacter sakazakii ATCC BAA-894 5549848 YP_001439468.1 CDS lacI NC_009778.1 3356262 3357335 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(3356262..3357335) Cronobacter sakazakii ATCC BAA-894 5550870 YP_001439469.1 CDS lamB NC_009778.1 3357725 3358876 D porin involved in the transport of maltose and maltodextrins; maltoporin 3357725..3358876 Cronobacter sakazakii ATCC BAA-894 5549489 YP_001439470.1 CDS ESA_03416 NC_009778.1 3359082 3359399 R KEGG: ypn:YPN_3053 2.3e-29 PTS transport protein K02778; COG: COG1264 Phosphotransferase system IIB components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3359082..3359399) Cronobacter sakazakii ATCC BAA-894 5549590 YP_001439471.1 CDS ESA_03417 NC_009778.1 3359469 3361529 R KEGG: ypm:YP_3549 0. bgaB; puative beta-galactosidase K01190; COG: COG1874 Beta-galactosidase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3359469..3361529) Cronobacter sakazakii ATCC BAA-894 5549728 YP_001439472.1 CDS ESA_03418 NC_009778.1 3361626 3362825 R KEGG: yps:YPTB3098 2.0e-174 putative galactosidase K01224; COG: COG3867 Arabinogalactan endo-1,4-beta-galactosidase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3361626..3362825) Cronobacter sakazakii ATCC BAA-894 5549646 YP_001439473.1 CDS ESA_03419 NC_009778.1 3362830 3363681 R KEGG: cya:CYA_1846 0.00032 modB; molybdate ABC transporter, permease protein K02018; COG: COG3833 ABC-type maltose transport systems, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3362830..3363681) Cronobacter sakazakii ATCC BAA-894 5549526 YP_001439474.1 CDS ESA_03420 NC_009778.1 3363691 3364974 R KEGG: pac:PPA0505 2.7e-05 ABC transporter, putative molybdenum transport system K02017:K02018; COG: COG1175 ABC-type sugar transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3363691..3364974) Cronobacter sakazakii ATCC BAA-894 5550284 YP_001439475.1 CDS ESA_03421 NC_009778.1 3365084 3366319 R COG: COG2182 Maltose-binding periplasmic proteins/domains; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3365084..3366319) Cronobacter sakazakii ATCC BAA-894 5549490 YP_001439476.1 CDS ESA_03422 NC_009778.1 3366667 3367776 D KEGG: bpm:BURPS1710b_1040 3.6e-104 ABC sugar transporter, ATP-binding protein K02023; COG: COG3839 ABC-type sugar transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein 3366667..3367776 Cronobacter sakazakii ATCC BAA-894 5549459 YP_001439477.1 CDS ESA_03423 NC_009778.1 3367914 3368270 D involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 3367914..3368270 Cronobacter sakazakii ATCC BAA-894 5549632 YP_001439478.1 CDS ESA_03424 NC_009778.1 3368305 3368469 R COG: COG5457 Uncharacterized conserved small protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3368305..3368469) Cronobacter sakazakii ATCC BAA-894 5549561 YP_001439479.1 CDS ESA_03425 NC_009778.1 3368499 3370064 D KEGG: bur:Bcep18194_B1266 2.2e-81 transcriptional regulator, GntR family with aminotransferase activity K00825; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: cytoplasmic, score: 23; hypothetical protein 3368499..3370064 Cronobacter sakazakii ATCC BAA-894 5550297 YP_001439480.1 CDS ESA_03426 NC_009778.1 3370118 3371383 D COG: COG2733 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3370118..3371383 Cronobacter sakazakii ATCC BAA-894 5550191 YP_001439481.1 CDS ESA_03427 NC_009778.1 3371391 3371885 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3371391..3371885) Cronobacter sakazakii ATCC BAA-894 5549599 YP_001439482.1 CDS ESA_03428 NC_009778.1 3372505 3373545 D COG: COG3209 Rhs family protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3372505..3373545 Cronobacter sakazakii ATCC BAA-894 5549587 YP_001439483.1 CDS ESA_03429 NC_009778.1 3373539 3373796 D Psort location: cytoplasmic, score: 23; hypothetical protein 3373539..3373796 Cronobacter sakazakii ATCC BAA-894 5549445 YP_001439484.1 CDS ESA_03430 NC_009778.1 3373833 3374084 D Psort location: cytoplasmic, score: 23; hypothetical protein 3373833..3374084 Cronobacter sakazakii ATCC BAA-894 5551912 YP_001439485.1 CDS ESA_03432 NC_009778.1 3375509 3375835 R COG: NOG11501 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3375509..3375835) Cronobacter sakazakii ATCC BAA-894 5550205 YP_001439486.1 CDS ESA_03433 NC_009778.1 3376430 3376855 R COG: NOG34707 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3376430..3376855) Cronobacter sakazakii ATCC BAA-894 5552453 YP_001439487.1 CDS ESA_03434 NC_009778.1 3376858 3377556 R COG: NOG26472 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3376858..3377556) Cronobacter sakazakii ATCC BAA-894 5549506 YP_001439488.1 CDS ESA_03436 NC_009778.1 3378432 3379448 D COG: NOG33447 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3378432..3379448 Cronobacter sakazakii ATCC BAA-894 5549709 YP_001439489.1 CDS ESA_03437 NC_009778.1 3379448 3380026 D KEGG: psp:PSPPH_0331 3.7e-22 ubiquinone/menaquinone biosynthesis methyltransferase UbiE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 3379448..3380026 Cronobacter sakazakii ATCC BAA-894 5551732 YP_001439490.1 CDS ESA_03438 NC_009778.1 3380135 3381154 D KEGG: eci:UTI89_C4876 4.2e-156 yjgB; putative oxidoreductase K00100; COG: COG1064 Zn-dependent alcohol dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 3380135..3381154 Cronobacter sakazakii ATCC BAA-894 5550871 YP_001439491.1 CDS ESA_03439 NC_009778.1 3381568 3383232 R COG: KOG2813 Predicted molecular chaperone, contains DnaJ domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3381568..3383232) Cronobacter sakazakii ATCC BAA-894 5550877 YP_001439492.1 CDS ESA_03440 NC_009778.1 3383812 3384726 R KEGG: rle:RL2900 2.8e-65 dhaK; putative dihydroxyacetone kinase K00863; COG: COG2376 Dihydroxyacetone kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3383812..3384726) Cronobacter sakazakii ATCC BAA-894 5549849 YP_001439493.1 CDS ESA_03441 NC_009778.1 3384683 3385492 R KEGG: rde:RD1_3702 1.5e-71 dihydroxyacetone kinase K00863; COG: COG2376 Dihydroxyacetone kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3384683..3385492) Cronobacter sakazakii ATCC BAA-894 5549019 YP_001439494.1 CDS ESA_03442 NC_009778.1 3385517 3385984 R Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(3385517..3385984) Cronobacter sakazakii ATCC BAA-894 5550910 YP_001439495.1 CDS ESA_03443 NC_009778.1 3386049 3387131 R COG: COG0795 Predicted permeases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3386049..3387131) Cronobacter sakazakii ATCC BAA-894 5550195 YP_001439496.1 CDS ESA_03444 NC_009778.1 3387118 3388230 R COG: COG0795 Predicted permeases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3387118..3388230) Cronobacter sakazakii ATCC BAA-894 5550865 YP_001439497.1 CDS ESA_03445 NC_009778.1 3388500 3390011 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 3388500..3390011 Cronobacter sakazakii ATCC BAA-894 5550873 YP_001439498.1 CDS ESA_03446 NC_009778.1 3390193 3390654 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 3390193..3390654 Cronobacter sakazakii ATCC BAA-894 5552277 YP_001439499.1 CDS valS NC_009778.1 3390657 3393512 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 3390657..3393512 Cronobacter sakazakii ATCC BAA-894 5550887 YP_001439500.1 CDS ESA_03448 NC_009778.1 3393628 3394830 R COG: COG4269 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(3393628..3394830) Cronobacter sakazakii ATCC BAA-894 5550913 YP_001439501.1 CDS ESA_03449 NC_009778.1 3395022 3395528 D KEGG: stm:STM4473 5.4e-69 yjgM; putative acetyltransferase K03828; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 3395022..3395528 Cronobacter sakazakii ATCC BAA-894 5550918 YP_001439502.1 CDS ESA_03450 NC_009778.1 3395577 3396383 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3395577..3396383) Cronobacter sakazakii ATCC BAA-894 5550952 YP_001439503.1 CDS ESA_03451 NC_009778.1 3396428 3397192 R KEGG: stm:STM4471 5.5e-108 miaE; hydroxylase for synthesis of 2-methylTHIo-cis-ribozeatin in tRNA K06169; COG: COG4445 Hydroxylase for synthesis of 2-methylTHIo-cis-ribozeatin in tRNA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3396428..3397192) Cronobacter sakazakii ATCC BAA-894 5550932 YP_001439504.1 CDS ESA_03452 NC_009778.1 3397240 3397659 R COG: COG3076 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3397240..3397659) Cronobacter sakazakii ATCC BAA-894 5550894 YP_001439505.1 CDS ESA_03453 NC_009778.1 3397823 3398827 D KEGG: spt:SPA4269 4.4e-154 argI; orniTHIne carbamoyltransferase K00611; COG: COG0078 OrniTHIne carbamoyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 3397823..3398827 Cronobacter sakazakii ATCC BAA-894 5550912 YP_001439506.1 CDS ESA_03454 NC_009778.1 3399162 3399614 R COG: COG2731 Beta-galactosidase, beta subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3399162..3399614) Cronobacter sakazakii ATCC BAA-894 5550807 YP_001439507.1 CDS ESA_03455 NC_009778.1 3399777 3400745 D COG: NOG33447 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3399777..3400745 Cronobacter sakazakii ATCC BAA-894 5550969 YP_001439508.1 CDS ESA_03456 NC_009778.1 3400745 3401323 D KEGG: psp:PSPPH_0331 3.7e-22 ubiquinone/menaquinone biosynthesis methyltransferase UbiE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 3400745..3401323 Cronobacter sakazakii ATCC BAA-894 5551001 YP_001439509.1 CDS ESA_03457 NC_009778.1 3401432 3402451 D KEGG: eci:UTI89_C4876 4.2e-156 yjgB; putative oxidoreductase K00100; COG: COG1064 Zn-dependent alcohol dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 3401432..3402451 Cronobacter sakazakii ATCC BAA-894 5550981 YP_001439510.1 CDS ESA_03458 NC_009778.1 3402865 3404529 R COG: KOG2813 Predicted molecular chaperone, contains DnaJ domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3402865..3404529) Cronobacter sakazakii ATCC BAA-894 5551032 YP_001439511.1 CDS ESA_03459 NC_009778.1 3405109 3406788 R KEGG: rle:RL2900 2.7e-145 dhaK; putative dihydroxyacetone kinase K00863; COG: COG2376 Dihydroxyacetone kinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3405109..3406788) Cronobacter sakazakii ATCC BAA-894 5550943 YP_001439512.1 CDS ESA_03461 NC_009778.1 3406813 3407280 R Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(3406813..3407280) Cronobacter sakazakii ATCC BAA-894 5551074 YP_001439513.1 CDS ESA_03460 NC_009778.1 3406912 3407415 D Psort location: nuclear, score: 23; hypothetical protein 3406912..3407415 Cronobacter sakazakii ATCC BAA-894 5551030 YP_001439514.1 CDS ESA_03463 NC_009778.1 3408413 3409525 R COG: COG0795 Predicted permeases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3408413..3409525) Cronobacter sakazakii ATCC BAA-894 5551084 YP_001439515.1 CDS ESA_03464 NC_009778.1 3409795 3411306 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 3409795..3411306 Cronobacter sakazakii ATCC BAA-894 5551014 YP_001439516.1 CDS ESA_03465 NC_009778.1 3411488 3411949 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 3411488..3411949 Cronobacter sakazakii ATCC BAA-894 5551046 YP_001439517.1 CDS valS NC_009778.1 3411952 3414807 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 3411952..3414807 Cronobacter sakazakii ATCC BAA-894 5551107 YP_001439518.1 CDS ESA_03467 NC_009778.1 3414923 3416125 R COG: COG4269 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(3414923..3416125) Cronobacter sakazakii ATCC BAA-894 5551026 YP_001439519.1 CDS ESA_03468 NC_009778.1 3416317 3416823 D KEGG: stm:STM4473 5.4e-69 yjgM; putative acetyltransferase K03828; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 3416317..3416823 Cronobacter sakazakii ATCC BAA-894 5551130 YP_001439520.1 CDS ESA_03469 NC_009778.1 3416872 3417678 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3416872..3417678) Cronobacter sakazakii ATCC BAA-894 5551158 YP_001439521.1 CDS ESA_03470 NC_009778.1 3417723 3418487 R KEGG: stm:STM4471 5.5e-108 miaE; hydroxylase for synthesis of 2-methylTHIo-cis-ribozeatin in tRNA K06169; COG: COG4445 Hydroxylase for synthesis of 2-methylTHIo-cis-ribozeatin in tRNA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3417723..3418487) Cronobacter sakazakii ATCC BAA-894 5551075 YP_001439522.1 CDS ESA_03471 NC_009778.1 3418535 3418954 R COG: COG3076 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3418535..3418954) Cronobacter sakazakii ATCC BAA-894 5549220 YP_001439523.1 CDS ESA_03472 NC_009778.1 3419118 3420122 D KEGG: spt:SPA4269 4.4e-154 argI; orniTHIne carbamoyltransferase K00611; COG: COG0078 OrniTHIne carbamoyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 3419118..3420122 Cronobacter sakazakii ATCC BAA-894 5549225 YP_001439524.1 CDS ESA_03474 NC_009778.1 3420457 3420909 R COG: COG2731 Beta-galactosidase, beta subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3420457..3420909) Cronobacter sakazakii ATCC BAA-894 5551233 YP_001439525.1 CDS ESA_03473 NC_009778.1 3420889 3421212 D Psort location: cytoplasmic, score: 23; hypothetical protein 3420889..3421212 Cronobacter sakazakii ATCC BAA-894 5551189 YP_001439526.1 CDS ESA_03475 NC_009778.1 3421446 3422801 D catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 3421446..3422801 Cronobacter sakazakii ATCC BAA-894 5551210 YP_001439527.1 CDS ESA_03476 NC_009778.1 3422812 3423723 D reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3422812..3423723 Cronobacter sakazakii ATCC BAA-894 5551190 YP_001439528.1 CDS ESA_03477 NC_009778.1 3423760 3424764 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 3423760..3424764 Cronobacter sakazakii ATCC BAA-894 5551219 YP_001439529.1 CDS ESA_03478 NC_009778.1 3424813 3426216 D COG: COG1288 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein 3424813..3426216 Cronobacter sakazakii ATCC BAA-894 5551207 YP_001439530.1 CDS ESA_03479 NC_009778.1 3426223 3426378 D Psort location: mitochondrial, score: 23; hypothetical protein 3426223..3426378 Cronobacter sakazakii ATCC BAA-894 5551243 YP_001439531.1 CDS ESA_03480 NC_009778.1 3426385 3426864 D COG: COG1438 Arginine repressor; Psort location: cytoplasmic, score: 23; hypothetical protein 3426385..3426864 Cronobacter sakazakii ATCC BAA-894 5551198 YP_001439532.1 CDS pyrB NC_009778.1 3427118 3428053 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 3427118..3428053 Cronobacter sakazakii ATCC BAA-894 5551254 YP_001439533.1 CDS ESA_03482 NC_009778.1 3428064 3428525 D involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 3428064..3428525 Cronobacter sakazakii ATCC BAA-894 5551226 YP_001439534.1 CDS ESA_03483 NC_009778.1 3428599 3428985 D KEGG: ape:APE_1501.1 1.1e-22 ribonuclease UK114; COG: COG0251 Putative translation initiation inhibitor, yjgF family; Psort location: cytoplasmic, score: 23; hypothetical protein 3428599..3428985 Cronobacter sakazakii ATCC BAA-894 5551324 YP_001439535.1 CDS ESA_03484 NC_009778.1 3429038 3431191 R KEGG: eci:UTI89_C3435 0. hypothetical protein; COG: COG1032 Fe-S oxidoreductase; Psort location: nuclear, score: 23; hypothetical protein complement(3429038..3431191) Cronobacter sakazakii ATCC BAA-894 5549229 YP_001439536.1 CDS ESA_03485 NC_009778.1 3431315 3432079 R KEGG: bur:Bcep18194_C7048 0.0019 ferredoxin/oxidoreductase FAD/NAD(P)-binding K05784; COG: COG2375 Siderophore-interacting protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3431315..3432079) Cronobacter sakazakii ATCC BAA-894 5551300 YP_001439537.1 CDS ESA_03486 NC_009778.1 3432167 3432352 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3432167..3432352) Cronobacter sakazakii ATCC BAA-894 5551374 YP_001439538.1 CDS ESA_03487 NC_009778.1 3432427 3432852 D COG: COG1695 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 3432427..3432852 Cronobacter sakazakii ATCC BAA-894 5551387 YP_001439539.1 CDS ESA_03488 NC_009778.1 3432888 3434435 R KEGG: abo:ABO_1307 6.1e-10 sensor histidine kinase/respose regulator; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3432888..3434435) Cronobacter sakazakii ATCC BAA-894 5551404 YP_001439540.1 CDS ESA_03489 NC_009778.1 3434880 3436430 R KEGG: azo:azo3685 8.7e-15 putative hybrid sensor and regulator protein; COG: COG2202 FOG: PAS/PAC domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3434880..3436430) Cronobacter sakazakii ATCC BAA-894 5551302 YP_001439541.1 CDS ESA_03491 NC_009778.1 3436595 3437245 R KEGG: vfi:VFA0057 5.4e-20 sensor protein; COG: COG2199 FOG: GGDEF domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3436595..3437245) Cronobacter sakazakii ATCC BAA-894 5551311 YP_001439542.1 CDS ESA_03490 NC_009778.1 3437240 3437386 D Psort location: mitochondrial, score: 23; hypothetical protein 3437240..3437386 Cronobacter sakazakii ATCC BAA-894 5551443 YP_001439543.1 CDS ESA_03492 NC_009778.1 3437866 3439290 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3437866..3439290 Cronobacter sakazakii ATCC BAA-894 5551297 YP_001439544.1 CDS ESA_03494 NC_009778.1 3439315 3439470 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3439315..3439470) Cronobacter sakazakii ATCC BAA-894 5551401 YP_001439545.1 CDS ESA_03493 NC_009778.1 3439469 3441487 D KEGG: stm:STM3219 2.3e-299 fadH; 2,4-dieonyl-CoA reductase K00219; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein 3439469..3441487 Cronobacter sakazakii ATCC BAA-894 5551474 YP_001439546.1 CDS ESA_03495 NC_009778.1 3441942 3443072 R KEGG: ecs:ECs3966 4.1e-151 putative ribosomal RNA small subunit methyltransferase D K00564; COG: COG2813 16S RNA G1207 methylase RsmC; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3441942..3443072) Cronobacter sakazakii ATCC BAA-894 5551422 YP_001439547.1 CDS ESA_03496 NC_009778.1 3443158 3443670 D COG: COG1451 Predicted metal-dependent hydrolase; Psort location: cytoplasmic, score: 23; hypothetical protein 3443158..3443670 Cronobacter sakazakii ATCC BAA-894 5551027 YP_001439548.1 CDS ESA_03497 NC_009778.1 3443740 3444387 D COG: COG2949 Uncharacterized membrane protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3443740..3444387 Cronobacter sakazakii ATCC BAA-894 5549736 YP_001439549.1 CDS ESA_03498 NC_009778.1 3444471 3445469 D KEGG: ecp:ECP_3178 4.3e-140 hypothetical oxidoreductase YgjR; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 3444471..3445469 Cronobacter sakazakii ATCC BAA-894 5552438 YP_001439550.1 CDS ESA_03499 NC_009778.1 3445735 3446703 D COG: COG0861 Membrane protein TerC, possibly involved in tellurium resistance; Psort location: plasma membrane, score: 23; hypothetical protein 3445735..3446703 Cronobacter sakazakii ATCC BAA-894 5549760 YP_001439551.1 CDS ESA_03500 NC_009778.1 3446998 3448245 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3446998..3448245 Cronobacter sakazakii ATCC BAA-894 5549801 YP_001439552.1 CDS ESA_03501 NC_009778.1 3448278 3448820 R COG: NOG07878 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3448278..3448820) Cronobacter sakazakii ATCC BAA-894 5552410 YP_001439553.1 CDS ESA_03502 NC_009778.1 3448892 3450379 R KEGG: ecp:ECP_3182 7.6e-237 altronate hydrolase K01685; COG: COG2721 Altronate dehydratase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3448892..3450379) Cronobacter sakazakii ATCC BAA-894 5549351 YP_001439554.1 CDS ESA_03503 NC_009778.1 3450397 3451809 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3450397..3451809) Cronobacter sakazakii ATCC BAA-894 5548169 YP_001439555.1 CDS ESA_03504 NC_009778.1 3452280 3453581 D KEGG: fal:FRAAL6577 0.0064 hppA; pyrophosphate-energized proton pump (pyrophosphate-energized inorganic pyrophosphatase) (H+-PPase) (membrane-bound proton-translocating pyrophosphatase) K01507; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 3452280..3453581 Cronobacter sakazakii ATCC BAA-894 5552318 YP_001439556.1 CDS ESA_03505 NC_009778.1 3453695 3454474 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3453695..3454474 Cronobacter sakazakii ATCC BAA-894 5552037 YP_001439557.1 CDS ESA_03506 NC_009778.1 3454790 3455452 D KEGG: sab:SAB2386 1.2e-09 probable alkaline phosphatase K01077; COG: COG0586 Uncharacterized membrane-associated protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3454790..3455452 Cronobacter sakazakii ATCC BAA-894 5549338 YP_001439558.1 CDS ESA_03507 NC_009778.1 3455495 3455839 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3455495..3455839 Cronobacter sakazakii ATCC BAA-894 5548733 YP_001439559.1 CDS ESA_03508 NC_009778.1 3455977 3456360 D KEGG: eci:UTI89_C0735 0.0051 tolA; membrane spanning protein TolA K03646; COG: NOG17164 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3455977..3456360 Cronobacter sakazakii ATCC BAA-894 5549823 YP_001439560.1 CDS ESA_03509 NC_009778.1 3456396 3456698 D COG: COG4575 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3456396..3456698 Cronobacter sakazakii ATCC BAA-894 5552345 YP_001439561.1 CDS ESA_03510 NC_009778.1 3456701 3457099 D COG: COG5393 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3456701..3457099 Cronobacter sakazakii ATCC BAA-894 5548767 YP_001439562.1 CDS ESA_03511 NC_009778.1 3457096 3457392 D COG: NOG11454 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 3457096..3457392 Cronobacter sakazakii ATCC BAA-894 5548650 YP_001439563.1 CDS ESA_03512 NC_009778.1 3457517 3458167 R COG: NOG11500 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3457517..3458167) Cronobacter sakazakii ATCC BAA-894 5552423 YP_001439564.1 CDS ESA_03513 NC_009778.1 3458186 3458836 R COG: NOG11500 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3458186..3458836) Cronobacter sakazakii ATCC BAA-894 5551521 YP_001439565.1 CDS ESA_03514 NC_009778.1 3458951 3459502 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3458951..3459502) Cronobacter sakazakii ATCC BAA-894 5552327 YP_001439566.1 CDS ESA_03515 NC_009778.1 3459493 3461925 R COG: COG3188 P pilus assembly protein, porin PapC; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3459493..3461925) Cronobacter sakazakii ATCC BAA-894 5551529 YP_001439567.1 CDS ESA_03516 NC_009778.1 3461947 3462648 R member of the periplasmic pilus chaperone family of proteins; putative periplasmic chaperone protein complement(3461947..3462648) Cronobacter sakazakii ATCC BAA-894 5551587 YP_001439568.1 CDS ESA_03517 NC_009778.1 3462816 3463499 R COG: NOG11500 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3462816..3463499) Cronobacter sakazakii ATCC BAA-894 5552433 YP_001439569.1 CDS ESA_03518 NC_009778.1 3463612 3464271 R COG: NOG11500 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3463612..3464271) Cronobacter sakazakii ATCC BAA-894 5551166 YP_001439570.1 CDS ESA_03519 NC_009778.1 3464328 3465020 R COG: NOG11500 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3464328..3465020) Cronobacter sakazakii ATCC BAA-894 5548108 YP_001439571.1 CDS ESA_03520 NC_009778.1 3465089 3465544 R COG: NOG11500 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3465089..3465544) Cronobacter sakazakii ATCC BAA-894 5549431 YP_001439572.1 CDS ESA_03521 NC_009778.1 3465920 3466609 R KEGG: chu:CHU_2149 0.00014 CHU large protein; candidate retaining b-glycosidase, glycoside hydrolase family 5 protein K01238; COG: NOG11500 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3465920..3466609) Cronobacter sakazakii ATCC BAA-894 5548388 YP_001439573.1 CDS ESA_03522 NC_009778.1 3467212 3467604 D COG: COG2259 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3467212..3467604 Cronobacter sakazakii ATCC BAA-894 5551597 YP_001439574.1 CDS ESA_03523 NC_009778.1 3467680 3468666 D KEGG: eci:UTI89_C3540 7.2e-161 yqjG; putative transferase K07393; COG: COG0435 Predicted glutathione S-transferase; Psort location: cytoplasmic, score: 23; hypothetical protein 3467680..3468666 Cronobacter sakazakii ATCC BAA-894 5548370 YP_001439575.1 CDS ESA_03524 NC_009778.1 3468822 3469187 D COG: COG3152 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3468822..3469187 Cronobacter sakazakii ATCC BAA-894 5551557 YP_001439576.1 CDS ESA_03525 NC_009778.1 3469322 3470245 D phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 3469322..3470245 Cronobacter sakazakii ATCC BAA-894 5551638 YP_001439577.1 CDS ESA_03526 NC_009778.1 3470412 3471929 D COG: COG4580 Maltoporin (phage lambda and maltose receptor); Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3470412..3471929 Cronobacter sakazakii ATCC BAA-894 5551619 YP_001439578.1 CDS ESA_03527 NC_009778.1 3471893 3473371 D KEGG: ecp:ECP_2752 7.5e-214 PTS system, sucrose-specific IIBC component K02809:K02810; COG: COG1264 Phosphotransferase system IIB components; Psort location: plasma membrane, score: 23; hypothetical protein 3471893..3473371 Cronobacter sakazakii ATCC BAA-894 5551712 YP_001439579.1 CDS ESA_03528 NC_009778.1 3473371 3474780 D KEGG: ecp:ECP_2753 3.0e-171 sucrose-6-phosphate hydrolase K01193; COG: COG1621 Beta-fructosidases (levanase/invertase); Psort location: vesicles of secretory system, score: 9; hypothetical protein 3473371..3474780 Cronobacter sakazakii ATCC BAA-894 5551178 YP_001439580.1 CDS ESA_03529 NC_009778.1 3474809 3475822 D KEGG: efa:EF1922 6.6e-07 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 3474809..3475822 Cronobacter sakazakii ATCC BAA-894 5551734 YP_001439581.1 CDS ESA_03530 NC_009778.1 3475819 3476718 R COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3475819..3476718) Cronobacter sakazakii ATCC BAA-894 5551710 YP_001439582.1 CDS ESA_03531 NC_009778.1 3476821 3477522 D COG: COG1741 Pirin-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3476821..3477522 Cronobacter sakazakii ATCC BAA-894 5551776 YP_001439583.1 CDS ESA_03532 NC_009778.1 3477558 3477734 D Psort location: cytoplasmic, score: 23; hypothetical protein 3477558..3477734 Cronobacter sakazakii ATCC BAA-894 5551671 YP_001439584.1 CDS ESA_03533 NC_009778.1 3477603 3477830 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3477603..3477830) Cronobacter sakazakii ATCC BAA-894 5551676 YP_001439585.1 CDS ESA_03535 NC_009778.1 3478475 3479335 R KEGG: eci:UTI89_C3573 1.7e-136 yraL; hypothetical protein; COG: COG0313 Predicted methyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3478475..3479335) Cronobacter sakazakii ATCC BAA-894 5551789 YP_001439586.1 CDS ESA_03536 NC_009778.1 3479398 3481458 D KEGG: abo:ABO_1060 0.00024 rne; phosphoric diester hydrolase K08300; COG: COG3107 Putative lipoprotein; Psort location: nuclear, score: 23; hypothetical protein 3479398..3481458 Cronobacter sakazakii ATCC BAA-894 5551851 YP_001439587.1 CDS ESA_03538 NC_009778.1 3481455 3481673 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3481455..3481673) Cronobacter sakazakii ATCC BAA-894 5551863 YP_001439588.1 CDS ESA_03537 NC_009778.1 3481542 3481811 D KEGG: eci:UTI89_C3574 1.5e-34 yraN; hypothetical protein YraN K07460; COG: COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Psort location: cytoplasmic, score: 23; hypothetical protein 3481542..3481811 Cronobacter sakazakii ATCC BAA-894 5551929 YP_001439589.1 CDS ESA_03539 NC_009778.1 3481838 3482428 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3481838..3482428 Cronobacter sakazakii ATCC BAA-894 5551949 YP_001439590.1 CDS ESA_03540 NC_009778.1 3482438 3483013 D COG: COG2823 Predicted periplasmic or secreted lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3482438..3483013 Cronobacter sakazakii ATCC BAA-894 5551935 YP_001439591.1 CDS ESA_03541 NC_009778.1 3483323 3484366 R COG: COG0701 Predicted permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(3483323..3484366) Cronobacter sakazakii ATCC BAA-894 5552012 YP_001439592.1 CDS ESA_03542 NC_009778.1 3484443 3485093 R KEGG: bxe:Bxe_A0199 5.8e-12 hypothetical protein K00329; COG: COG0702 Predicted nucleoside-diphosphate-sugar epimerases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3484443..3485093) Cronobacter sakazakii ATCC BAA-894 5552269 YP_001439593.1 CDS ESA_03543 NC_009778.1 3485238 3485756 D KEGG: ecp:ECP_3241 1.5e-80 hypothetical protein YhbO (hypothetical protease) K05520; COG: COG0693 Putative intracellular protease/amidase; Psort location: cytoplasmic, score: 23; hypothetical protein 3485238..3485756 Cronobacter sakazakii ATCC BAA-894 5551966 YP_001439594.1 CDS ESA_03544 NC_009778.1 3485736 3486170 R COG: COG3787 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3485736..3486170) Cronobacter sakazakii ATCC BAA-894 5552015 YP_001439595.1 CDS ESA_03545 NC_009778.1 3486236 3486523 D KEGG: mca:MCA0838 0.0011 type I restriction-modification system, R subunit K01153; COG: COG2827 Predicted endonuclease containing a URI domain; Psort location: cytoplasmic, score: 23; GIY-YIG nuclease superfamily protein 3486236..3486523 Cronobacter sakazakii ATCC BAA-894 5552129 YP_001439596.1 CDS ESA_03546 NC_009778.1 3486526 3487029 R KEGG: sec:SC3213 9.8e-70 yhbS; putative ABC superfamily (membrane) transport protein K03824; COG: COG3153 Predicted acetyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3486526..3487029) Cronobacter sakazakii ATCC BAA-894 5552006 YP_001439597.1 CDS ESA_03547 NC_009778.1 3487023 3487487 R COG: COG3154 Putative lipid carrier protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3487023..3487487) Cronobacter sakazakii ATCC BAA-894 5549462 YP_001439598.1 CDS ESA_03548 NC_009778.1 3487796 3488791 D KEGG: ecp:ECP_3246 5.2e-167 putative protease YhbU precursor K08303; COG: COG0826 Collagenase and related proteases; Psort location: cytoplasmic, score: 23; hypothetical protein 3487796..3488791 Cronobacter sakazakii ATCC BAA-894 5549612 YP_001439599.1 CDS ESA_03549 NC_009778.1 3488802 3489680 D KEGG: eci:UTI89_C3586 1.8e-132 yhbV; hypothetical protein YhbV K01423; COG: COG0826 Collagenase and related proteases; Psort location: cytoplasmic, score: 23; hypothetical protein 3488802..3489680 Cronobacter sakazakii ATCC BAA-894 5549538 YP_001439600.1 CDS ESA_03550 NC_009778.1 3489833 3490843 D KEGG: eci:UTI89_C3587 1.4e-159 yhbW; hypothetical protein K00494; COG: COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3489833..3490843 Cronobacter sakazakii ATCC BAA-894 5549570 YP_001439601.1 CDS ESA_03551 NC_009778.1 3490887 3492131 R tryptophan transporter of high affinity; tryptophan permease complement(3490887..3492131) Cronobacter sakazakii ATCC BAA-894 5549675 YP_001439602.1 CDS ESA_03552 NC_009778.1 3492201 3492365 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3492201..3492365) Cronobacter sakazakii ATCC BAA-894 5549542 YP_001439604.1 CDS ESA_03554 NC_009778.1 3492413 3494320 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3492413..3494320) Cronobacter sakazakii ATCC BAA-894 5549509 YP_001439605.1 CDS ESA_03556 NC_009778.1 3494501 3495385 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3494501..3495385) Cronobacter sakazakii ATCC BAA-894 5549453 YP_001439606.1 CDS ESA_03555 NC_009778.1 3495346 3497343 D Psort location: cytoplasmic, score: 23; hypothetical protein 3495346..3497343 Cronobacter sakazakii ATCC BAA-894 5549568 YP_001439607.1 CDS ESA_03557 NC_009778.1 3495502 3497574 R KEGG: eci:UTI89_C3594 0. pnp; polyribonucleotide nucleotidyltransferase K00962; COG: COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Psort location: cytoplasmic, score: 23; polynucleotide phosphorylase/polyadenylase complement(3495502..3497574) Cronobacter sakazakii ATCC BAA-894 5549678 YP_003856786.1 CDS ESA_04500 NC_009778.1 3497882 3498151 R 30S ribosomal protein S15 complement(3497882..3498151) Cronobacter sakazakii ATCC BAA-894 9711815 YP_001439608.1 CDS truB NC_009778.1 3498295 3499239 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3498295..3499239) Cronobacter sakazakii ATCC BAA-894 5551238 YP_001439609.1 CDS rbfA NC_009778.1 3499239 3499691 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3499239..3499691) Cronobacter sakazakii ATCC BAA-894 5551321 YP_001439610.1 CDS infB NC_009778.1 3499776 3502487 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3499776..3502487) Cronobacter sakazakii ATCC BAA-894 5551589 YP_001439611.1 CDS nusA NC_009778.1 3502512 3503999 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3502512..3503999) Cronobacter sakazakii ATCC BAA-894 5552391 YP_001439612.1 CDS ESA_03563 NC_009778.1 3504027 3504509 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3504027..3504509) Cronobacter sakazakii ATCC BAA-894 5549425 YP_001439613.1 CDS secG NC_009778.1 3504958 3505290 R KEGG: lpn:lpg1509 0.0046 D-alanyl-D-alanine carboxypeptidase K07258; COG: COG1314 Preprotein translocase subunit SecG; Psort location: endoplasmic reticulum, score: 9; preprotein translocase subunit SecG complement(3504958..3505290) Cronobacter sakazakii ATCC BAA-894 5550837 YP_001439614.1 CDS glmM NC_009778.1 3505514 3506851 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3505514..3506851) Cronobacter sakazakii ATCC BAA-894 5550809 YP_001439615.1 CDS folP NC_009778.1 3506844 3507698 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3506844..3507698) Cronobacter sakazakii ATCC BAA-894 5550776 YP_001439616.1 CDS hflB NC_009778.1 3507783 3509717 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3507783..3509717) Cronobacter sakazakii ATCC BAA-894 5550785 YP_001439617.1 CDS rrmJ NC_009778.1 3509774 3510415 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J complement(3509774..3510415) Cronobacter sakazakii ATCC BAA-894 5550786 YP_001439618.1 CDS ESA_03571 NC_009778.1 3510528 3510821 D RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3510528..3510821 Cronobacter sakazakii ATCC BAA-894 5550740 YP_001439619.1 CDS greA NC_009778.1 3511042 3511518 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3511042..3511518) Cronobacter sakazakii ATCC BAA-894 5550788 YP_001439620.1 CDS ESA_03573 NC_009778.1 3511766 3513199 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3511766..3513199 Cronobacter sakazakii ATCC BAA-894 5550760 YP_001439621.1 CDS ESA_03574 NC_009778.1 3513202 3513864 D response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 3513202..3513864 Cronobacter sakazakii ATCC BAA-894 5550789 YP_001439622.1 CDS ESA_03575 NC_009778.1 3513861 3514925 D KEGG: yps:YPTB0468 2.7e-113 basS, prmB; two-component system sensor protein K07643; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; sensor protein BasS/PmrB 3513861..3514925 Cronobacter sakazakii ATCC BAA-894 5550799 YP_001439623.1 CDS obgE NC_009778.1 3514987 3516159 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3514987..3516159) Cronobacter sakazakii ATCC BAA-894 5550729 YP_001439624.1 CDS ESA_03577 NC_009778.1 3516176 3517141 R COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(3516176..3517141) Cronobacter sakazakii ATCC BAA-894 5550714 YP_001439625.1 CDS rpmA NC_009778.1 3517237 3517494 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3517237..3517494) Cronobacter sakazakii ATCC BAA-894 5550738 YP_001439626.1 CDS ESA_03579 NC_009778.1 3517559 3517876 D KEGG: bba:Bd0348 0.0092 acyltransferase K00655; Psort location: cytoplasmic, score: 23; hypothetical protein 3517559..3517876 Cronobacter sakazakii ATCC BAA-894 5550720 YP_001439627.1 CDS ESA_03580 NC_009778.1 3518083 3519054 D KEGG: sfx:S3445 8.2e-153 ispB; octaprenyl diphosphate synthase K02523; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: cytoplasmic, score: 23; hypothetical protein 3518083..3519054 Cronobacter sakazakii ATCC BAA-894 5551887 YP_001439628.1 CDS ESA_03581 NC_009778.1 3519359 3519622 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3519359..3519622 Cronobacter sakazakii ATCC BAA-894 5552443 YP_001439629.1 CDS ESA_03582 NC_009778.1 3519736 3520995 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3519736..3520995) Cronobacter sakazakii ATCC BAA-894 5552436 YP_001439630.1 CDS ESA_03583 NC_009778.1 3521048 3521305 R COG: COG5007 Predicted transcriptional regulator, BolA superfamily; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3521048..3521305) Cronobacter sakazakii ATCC BAA-894 5552441 YP_001439631.1 CDS ESA_03584 NC_009778.1 3521430 3521732 R COG: COG3113 Predicted NTP binding protein (contains STAS domain); Psort location: cytoplasmic, score: 23; hypothetical protein complement(3521430..3521732) Cronobacter sakazakii ATCC BAA-894 5552208 YP_001439632.1 CDS ESA_03585 NC_009778.1 3521732 3522367 R COG: COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3521732..3522367) Cronobacter sakazakii ATCC BAA-894 5552159 YP_001439633.1 CDS ESA_03586 NC_009778.1 3522383 3522934 R COG: COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3522383..3522934) Cronobacter sakazakii ATCC BAA-894 5551705 YP_001439634.1 CDS ESA_03587 NC_009778.1 3522938 3523720 R COG: COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3522938..3523720) Cronobacter sakazakii ATCC BAA-894 5549588 YP_001439635.1 CDS ESA_03588 NC_009778.1 3523728 3524543 R ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF complement(3523728..3524543) Cronobacter sakazakii ATCC BAA-894 5549553 YP_001439636.1 CDS ESA_03589 NC_009778.1 3524777 3525754 D YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 3524777..3525754 Cronobacter sakazakii ATCC BAA-894 5549674 YP_001439637.1 CDS ESA_03590 NC_009778.1 3525751 3526755 D KEGG: sec:SC3253 6.1e-148 yrbH; putative polysialic acid capsule expression protein K06041; COG: COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Psort location: cytoplasmic, score: 23; D-arabinose 5-phosphate isomerase 3525751..3526755 Cronobacter sakazakii ATCC BAA-894 5552136 YP_001439638.1 CDS ESA_03591 NC_009778.1 3526771 3527337 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3526771..3527337 Cronobacter sakazakii ATCC BAA-894 5550749 YP_001439639.1 CDS ESA_03592 NC_009778.1 3527334 3527909 D COG: COG3117 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3527334..3527909 Cronobacter sakazakii ATCC BAA-894 5550721 YP_001439640.1 CDS ESA_03593 NC_009778.1 3527878 3528435 D LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3527878..3528435 Cronobacter sakazakii ATCC BAA-894 5550725 YP_001439641.1 CDS ESA_03594 NC_009778.1 3528442 3529167 D KEGG: pen:PSEEN1094 8.8e-85 ABC transporter, ATP-binding protein; COG: COG1137 ABC-type (unclassified) transport system, ATPase component; Psort location: cytoplasmic, score: 23; putative ABC transporter ATP-binding protein YhbG 3528442..3529167 Cronobacter sakazakii ATCC BAA-894 5552480 YP_001439642.1 CDS ESA_03595 NC_009778.1 3529263 3530702 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3529263..3530702 Cronobacter sakazakii ATCC BAA-894 5550688 YP_001439643.1 CDS ESA_03596 NC_009778.1 3530725 3531012 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 3530725..3531012 Cronobacter sakazakii ATCC BAA-894 5552053 YP_001439644.1 CDS ESA_03597 NC_009778.1 3531095 3531580 D KEGG: stm:STM3322 1.2e-73 ptsN; sugar specific PTS family, enzyme IIA, also regulates N metabolism K02806; COG: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); Psort location: nuclear, score: 23; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3531095..3531580 Cronobacter sakazakii ATCC BAA-894 5552332 YP_001439645.1 CDS ESA_03598 NC_009778.1 3531630 3532499 D KEGG: reh:H16_A0381 2.6e-60 predicted P-loop-containing kinase K01009; COG: COG1660 Predicted P-loop-containing kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 3531630..3532499 Cronobacter sakazakii ATCC BAA-894 5550717 YP_001439646.1 CDS ESA_03599 NC_009778.1 3532496 3532768 D KEGG: aha:AHA_3919 1.6e-28 multiphosphoryl transfer protein (MTP) K00924; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: cytoplasmic, score: 23; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3532496..3532768 Cronobacter sakazakii ATCC BAA-894 5550649 YP_001439647.1 CDS mtgA NC_009778.1 3532780 3533505 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3532780..3533505) Cronobacter sakazakii ATCC BAA-894 5550677 YP_001439648.1 CDS ESA_03601 NC_009778.1 3533502 3534155 R KEGG: gvi:glr2813 0.00078 probable protease K05520; COG: COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis; Psort location: endoplasmic reticulum, score: 9; isoprenoid biosynthesis protein with amidotransferase-like domain complement(3533502..3534155) Cronobacter sakazakii ATCC BAA-894 5552156 YP_001439649.1 CDS ESA_03603 NC_009778.1 3534392 3536731 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3534392..3536731) Cronobacter sakazakii ATCC BAA-894 5550678 YP_001439650.1 CDS ESA_03604 NC_009778.1 3536843 3537778 R KEGG: eci:UTI89_C3647 2.1e-131 yhcC; hypothetical protein; COG: COG1242 Predicted Fe-S oxidoreductase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3536843..3537778) Cronobacter sakazakii ATCC BAA-894 5550706 YP_001439651.1 CDS ESA_03605 NC_009778.1 3538143 3538679 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3538143..3538679) Cronobacter sakazakii ATCC BAA-894 5552254 YP_001439652.1 CDS gltB NC_009778.1 3538713 3542921 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3538713..3542921 Cronobacter sakazakii ATCC BAA-894 5550639 YP_001439653.1 CDS gltD NC_009778.1 3542935 3544353 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3542935..3544353 Cronobacter sakazakii ATCC BAA-894 5550630 YP_001439654.1 CDS ESA_03608 NC_009778.1 3544722 3547301 D KEGG: eci:UTI89_C2514 9.0e-52 yfaL; hypothetical protein YfaL precursor K07279; COG: COG3210 Large exoproteins involved in heme utilization or adhesion; Psort location: cytoplasmic, score: 23; hypothetical protein 3544722..3547301 Cronobacter sakazakii ATCC BAA-894 5550654 YP_001439655.1 CDS ESA_03609 NC_009778.1 3547353 3547817 R COG: COG2731 Beta-galactosidase, beta subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3547353..3547817) Cronobacter sakazakii ATCC BAA-894 5550633 YP_001439656.1 CDS ESA_03610 NC_009778.1 3547814 3548689 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3547814..3548689) Cronobacter sakazakii ATCC BAA-894 5550619 YP_001439657.1 CDS ESA_03611 NC_009778.1 3548844 3550334 R KEGG: cal:orf19.6141 3.4e-05 HXT1; high-affinity hexose (glucose) transporter K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; putative sialic acid transporter complement(3548844..3550334) Cronobacter sakazakii ATCC BAA-894 5550624 YP_001439658.1 CDS ESA_03612 NC_009778.1 3550431 3551309 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3550431..3551309) Cronobacter sakazakii ATCC BAA-894 5550625 YP_001439659.1 CDS ESA_03613 NC_009778.1 3551468 3552250 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3551468..3552250) Cronobacter sakazakii ATCC BAA-894 5550607 YP_001439660.1 CDS ESA_03614 NC_009778.1 3552359 3552850 R COG: COG2969 Stringent starvation protein B; Psort location: cytoplasmic, score: 23; ClpXP protease specificity-enhancing factor complement(3552359..3552850) Cronobacter sakazakii ATCC BAA-894 5550580 YP_001439661.1 CDS sspA NC_009778.1 3552856 3553497 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3552856..3553497) Cronobacter sakazakii ATCC BAA-894 5550574 YP_001439662.1 CDS rpsI NC_009778.1 3553811 3554209 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3553811..3554209) Cronobacter sakazakii ATCC BAA-894 5550578 YP_001439663.1 CDS rplM NC_009778.1 3554218 3554646 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3554218..3554646) Cronobacter sakazakii ATCC BAA-894 5550615 YP_001439664.1 CDS ESA_03618 NC_009778.1 3554897 3556033 R KEGG: reh:H16_A2322 4.1e-71 ATPase K01529; COG: COG1485 Predicted ATPase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3554897..3556033) Cronobacter sakazakii ATCC BAA-894 5550577 YP_001439665.1 CDS ESA_03619 NC_009778.1 3556108 3556635 D KEGG: eco:b3233 2.6e-62 yhcB; hypothetical protein K00424; COG: COG3105 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; cytochrome d ubiquinol oxidase subunit III 3556108..3556635 Cronobacter sakazakii ATCC BAA-894 5550550 YP_001439666.1 CDS ESA_03620 NC_009778.1 3556808 3558175 D KEGG: spt:SPA3215 1.6e-202 degQ; serine protease K04772; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Psort location: extracellular, including cell wall, score: 9; serine endoprotease 3556808..3558175 Cronobacter sakazakii ATCC BAA-894 5550521 YP_001439667.1 CDS ESA_03621 NC_009778.1 3558266 3559333 D KEGG: ecc:c3990 1.0e-154 degS; protease degS precursor K04691; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Psort location: extracellular, including cell wall, score: 9; serine endoprotease 3558266..3559333 Cronobacter sakazakii ATCC BAA-894 5550534 YP_001439668.1 CDS ESA_03622 NC_009778.1 3559394 3560332 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3559394..3560332) Cronobacter sakazakii ATCC BAA-894 5550528 YP_001439669.1 CDS ESA_03623 NC_009778.1 3560769 3561239 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3560769..3561239 Cronobacter sakazakii ATCC BAA-894 5550517 YP_001439670.1 CDS ESA_03624 NC_009778.1 3561604 3561867 D KEGG: tko:TK0217 0.0036 pyridoxine/pyridoxal 5-phosphate biosynthesis protein, SOR/SNZ family K06215; COG: NOG12178 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3561604..3561867 Cronobacter sakazakii ATCC BAA-894 5550507 YP_001439671.1 CDS ESA_03625 NC_009778.1 3561979 3562248 D COG: NOG30709 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3561979..3562248 Cronobacter sakazakii ATCC BAA-894 5550535 YP_001439672.1 CDS ESA_03626 NC_009778.1 3562319 3562591 R COG: COG2732 Barstar, RNAse (barnase) inhibitor; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3562319..3562591) Cronobacter sakazakii ATCC BAA-894 5550501 YP_001439673.1 CDS ESA_03627 NC_009778.1 3562637 3564175 R KEGG: eca:ECA0280 7.1e-131 succinate-semialdehyde dehydrogenase [NADP+] K00135; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3562637..3564175) Cronobacter sakazakii ATCC BAA-894 5550490 YP_001439674.1 CDS ESA_03628 NC_009778.1 3564175 3566148 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3564175..3566148) Cronobacter sakazakii ATCC BAA-894 5550504 YP_001439675.1 CDS ESA_03629 NC_009778.1 3566148 3567095 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3566148..3567095) Cronobacter sakazakii ATCC BAA-894 5550457 YP_001439676.1 CDS ESA_03630 NC_009778.1 3567088 3567291 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3567088..3567291) Cronobacter sakazakii ATCC BAA-894 5550500 YP_001439677.1 CDS ESA_03631 NC_009778.1 3567484 3568410 D KEGG: shn:Shewana3_3435 3.5e-09 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; putative DNA-binding transcriptional regulator 3567484..3568410 Cronobacter sakazakii ATCC BAA-894 5550475 YP_001439678.1 CDS tldD NC_009778.1 3568451 3569896 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3568451..3569896) Cronobacter sakazakii ATCC BAA-894 5550397 YP_001439679.1 CDS ESA_03633 NC_009778.1 3569982 3573824 R COG: COG3164 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3569982..3573824) Cronobacter sakazakii ATCC BAA-894 5550440 YP_001439680.1 CDS ESA_03634 NC_009778.1 3573843 3575312 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3573843..3575312) Cronobacter sakazakii ATCC BAA-894 5550494 YP_001439681.1 CDS ESA_03635 NC_009778.1 3575318 3575893 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3575318..3575893) Cronobacter sakazakii ATCC BAA-894 5550474 YP_001439682.1 CDS ESA_03636 NC_009778.1 3575903 3576391 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3575903..3576391) Cronobacter sakazakii ATCC BAA-894 5550436 YP_001439683.1 CDS ESA_03637 NC_009778.1 3576391 3577398 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3576391..3577398) Cronobacter sakazakii ATCC BAA-894 5550441 YP_001439684.1 CDS ESA_03638 NC_009778.1 3577460 3578503 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3577460..3578503) Cronobacter sakazakii ATCC BAA-894 5550431 YP_001439685.1 CDS ESA_03639 NC_009778.1 3578811 3580751 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3578811..3580751) Cronobacter sakazakii ATCC BAA-894 5550390 YP_001439686.1 CDS ESA_03640 NC_009778.1 3580946 3581959 D KEGG: eci:UTI89_C3684 1.1e-139 yhdH; protein YhdH K00001; COG: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3580946..3581959 Cronobacter sakazakii ATCC BAA-894 5550419 YP_001439687.1 CDS ESA_03641 NC_009778.1 3582063 3583067 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 3582063..3583067 Cronobacter sakazakii ATCC BAA-894 5550386 YP_001439688.1 CDS ESA_03642 NC_009778.1 3583068 3583670 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 3583068..3583670 Cronobacter sakazakii ATCC BAA-894 5550389 YP_001439689.1 CDS ESA_03643 NC_009778.1 3583791 3584354 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 3583791..3584354 Cronobacter sakazakii ATCC BAA-894 5550405 YP_001439690.1 CDS ESA_03644 NC_009778.1 3584376 3584852 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3584376..3584852 Cronobacter sakazakii ATCC BAA-894 5550377 YP_001439691.1 CDS ESA_03645 NC_009778.1 3584863 3586212 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3584863..3586212 Cronobacter sakazakii ATCC BAA-894 5550393 YP_001439692.1 CDS ESA_03646 NC_009778.1 3586312 3586560 D KEGG: spj:MGAS2096_Spy0220 0.0075 fasC; sensory transduction protein kinase FasC; COG: COG3924 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3586312..3586560 Cronobacter sakazakii ATCC BAA-894 5550376 YP_001439693.1 CDS panF NC_009778.1 3586550 3588004 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3586550..3588004 Cronobacter sakazakii ATCC BAA-894 5550321 YP_001439694.1 CDS prmA NC_009778.1 3588001 3588894 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3588001..3588894 Cronobacter sakazakii ATCC BAA-894 5550360 YP_001439695.1 CDS ESA_03649 NC_009778.1 3589109 3589372 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3589109..3589372 Cronobacter sakazakii ATCC BAA-894 5550361 YP_001439696.1 CDS ESA_03650 NC_009778.1 3589454 3590437 D KEGG: sec:SC3322 5.7e-161 yhdG, nifR3; putative TIM-barrel enzyme, possibly dehydrogenase K05540; COG: COG0042 tRNA-dihydrouridine synthase; Psort location: mitochondrial, score: 23; tRNA-dihydrouridine synthase B 3589454..3590437 Cronobacter sakazakii ATCC BAA-894 5550322 YP_001439697.1 CDS fis NC_009778.1 3590463 3590759 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3590463..3590759 Cronobacter sakazakii ATCC BAA-894 5550302 YP_001439698.1 CDS ESA_03652 NC_009778.1 3591083 3593179 D KEGG: shn:Shewana3_3829 4.2e-95 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2199 FOG: GGDEF domain; Psort location: plasma membrane, score: 23; hypothetical protein 3591083..3593179 Cronobacter sakazakii ATCC BAA-894 5550148 YP_001439699.1 CDS ESA_03654 NC_009778.1 3593231 3593872 R COG: COG1309 Transcriptional regulator; Psort location: cytoplasmic, score: 23; DNA-binding transcriptional regulator EnvR complement(3593231..3593872) Cronobacter sakazakii ATCC BAA-894 5550003 YP_001439700.1 CDS ESA_03653 NC_009778.1 3593720 3593941 D Psort location: nuclear, score: 23; hypothetical protein 3593720..3593941 Cronobacter sakazakii ATCC BAA-894 5550016 YP_001439701.1 CDS ESA_03655 NC_009778.1 3594253 3595395 D COG: COG0845 Membrane-fusion protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3594253..3595395 Cronobacter sakazakii ATCC BAA-894 5550355 YP_001439702.1 CDS ESA_03657 NC_009778.1 3598869 3599093 D COG: NOG14133 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3598869..3599093 Cronobacter sakazakii ATCC BAA-894 5552291 YP_001439703.1 CDS ESA_03658 NC_009778.1 3599241 3599381 R Psort location: nuclear, score: 23; hypothetical protein complement(3599241..3599381) Cronobacter sakazakii ATCC BAA-894 5550043 YP_001439704.1 CDS ESA_03659 NC_009778.1 3599574 3600599 D KEGG: bur:Bcep18194_A4762 3.0e-16 ABC amino acid transporter, periplasmic ligand binding protein K01713; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3599574..3600599 Cronobacter sakazakii ATCC BAA-894 5550326 YP_001439705.1 CDS ESA_03660 NC_009778.1 3600669 3601850 D KEGG: sma:SAV6546 1.6e-17 putative ABC transporter permease K02028; COG: COG4597 ABC-type amino acid transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3600669..3601850 Cronobacter sakazakii ATCC BAA-894 5550455 YP_001439706.1 CDS ESA_03661 NC_009778.1 3601916 3602950 D KEGG: sma:SAV6546 1.1e-22 putative ABC transporter permease K02028; COG: COG0765 ABC-type amino acid transport system, permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3601916..3602950 Cronobacter sakazakii ATCC BAA-894 5552376 YP_001439707.1 CDS ESA_03662 NC_009778.1 3602959 3603717 D KEGG: ecs:ECs4144 9.9e-125 putative ATP-binding component of a transport system K02028; COG: COG1126 ABC-type polar amino acid transport system, ATPase component; Psort location: cytoplasmic, score: 23; hypothetical protein 3602959..3603717 Cronobacter sakazakii ATCC BAA-894 5550399 YP_001439710.1 CDS purH NC_009778.1 3609949 3611538 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3609949..3611538 Cronobacter sakazakii ATCC BAA-894 5550524 YP_001439711.1 CDS ESA_03671 NC_009778.1 3611552 3612850 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 3611552..3612850 Cronobacter sakazakii ATCC BAA-894 5550489 YP_001439712.1 CDS ESA_03672 NC_009778.1 3612915 3613556 R COG: NOG06219 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3612915..3613556) Cronobacter sakazakii ATCC BAA-894 5550506 YP_001439713.1 CDS ESA_03673 NC_009778.1 3613619 3613891 R histone-like DNA-binding protein; transcriptional regulator HU subunit alpha complement(3613619..3613891) Cronobacter sakazakii ATCC BAA-894 5552342 YP_001439714.1 CDS ESA_03674 NC_009778.1 3614078 3614668 R COG: COG3068 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3614078..3614668) Cronobacter sakazakii ATCC BAA-894 5550591 YP_001439715.1 CDS ESA_03675 NC_009778.1 3614712 3615383 R Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V complement(3614712..3615383) Cronobacter sakazakii ATCC BAA-894 5550585 YP_001439716.1 CDS hemE NC_009778.1 3615393 3616457 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(3615393..3616457) Cronobacter sakazakii ATCC BAA-894 5550632 YP_001439717.1 CDS nudC NC_009778.1 3616499 3617272 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(3616499..3617272) Cronobacter sakazakii ATCC BAA-894 5550612 YP_001439718.1 CDS ESA_03678 NC_009778.1 3617363 3617878 D binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 3617363..3617878 Cronobacter sakazakii ATCC BAA-894 5550604 YP_001439719.1 CDS ESA_03679 NC_009778.1 3618157 3620058 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 3618157..3620058 Cronobacter sakazakii ATCC BAA-894 5550546 YP_001439720.1 CDS ESA_03680 NC_009778.1 3620058 3620690 D catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 3620058..3620690 Cronobacter sakazakii ATCC BAA-894 5550601 YP_001439721.1 CDS ESA_03681 NC_009778.1 3620683 3621432 D KEGG: eci:UTI89_C3827 4.6e-95 THIF; adenylyltransferase ThiF K03148; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and THIamine biosynthesis family 2; Psort location: cytoplasmic, score: 23; hypothetical protein 3620683..3621432 Cronobacter sakazakii ATCC BAA-894 5550617 YP_001439722.1 CDS ESA_03682 NC_009778.1 3621422 3621622 D COG: COG2104 Sulfur transfer protein involved in THIamine biosynthesis; Psort location: cytoplasmic, score: 23; hypothetical protein 3621422..3621622 Cronobacter sakazakii ATCC BAA-894 5552497 YP_001439723.1 CDS thiG NC_009778.1 3621624 3622394 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 3621624..3622394 Cronobacter sakazakii ATCC BAA-894 5550581 YP_001439724.1 CDS thiH NC_009778.1 3622391 3623524 D in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 3622391..3623524 Cronobacter sakazakii ATCC BAA-894 5550697 YP_001439725.1 CDS ESA_03685 NC_009778.1 3623778 3624146 D KEGG: plu:plu2754 4.8e-29 celA; PTS system, cellobiose-specific IIB component K02760; COG: COG1440 Phosphotransferase system cellobiose-specific component IIB; Psort location: cytoplasmic, score: 23; hypothetical protein 3623778..3624146 Cronobacter sakazakii ATCC BAA-894 5550687 YP_001439726.1 CDS ESA_03686 NC_009778.1 3624151 3624468 D KEGG: plu:plu2756 1.2e-32 celC; PTS system, cellobiose-specific IIA component (EIIA-CEL) (cellobiose-permease IIA component) (phosphotransferase enzyme II, A component) (EIII-CEL) K02759; COG: COG1447 Phosphotransferase system cellobiose-specific component IIA; Psort location: cytoplasmic, score: 23; hypothetical protein 3624151..3624468 Cronobacter sakazakii ATCC BAA-894 5550712 YP_001439727.1 CDS ESA_03687 NC_009778.1 3624505 3625698 D KEGG: reh:H16_B2551 1.4e-07 alkA; DNA-3-methyladenine glycosylase II, adenosine deaminase K01247; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: plasma membrane, score: 23; hypothetical protein 3624505..3625698 Cronobacter sakazakii ATCC BAA-894 5550669 YP_001439728.1 CDS ESA_03688 NC_009778.1 3625592 3626674 R KEGG: xcb:XC_1376 2.2e-05 putative carboxymethylenebutenolidase K01061; COG: COG4188 Predicted dienelactone hydrolase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3625592..3626674) Cronobacter sakazakii ATCC BAA-894 5550751 YP_001439729.1 CDS ESA_03689 NC_009778.1 3626817 3631040 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(3626817..3631040) Cronobacter sakazakii ATCC BAA-894 5550795 YP_001439730.1 CDS rpoB NC_009778.1 3631117 3635187 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(3631117..3635187) Cronobacter sakazakii ATCC BAA-894 5550685 YP_001439731.1 CDS ESA_03691 NC_009778.1 3635367 3635870 D Psort location: mitochondrial, score: 23; hypothetical protein 3635367..3635870 Cronobacter sakazakii ATCC BAA-894 5550829 YP_001439732.1 CDS rplL NC_009778.1 3635463 3635831 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(3635463..3635831) Cronobacter sakazakii ATCC BAA-894 5550825 YP_001439733.1 CDS rplJ NC_009778.1 3635898 3636395 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(3635898..3636395) Cronobacter sakazakii ATCC BAA-894 5550332 YP_001439734.1 CDS rplA NC_009778.1 3636687 3637391 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(3636687..3637391) Cronobacter sakazakii ATCC BAA-894 5550303 YP_001439735.1 CDS ESA_03694 NC_009778.1 3636876 3637847 D Psort location: mitochondrial, score: 23; hypothetical protein 3636876..3637847 Cronobacter sakazakii ATCC BAA-894 5550236 YP_001439736.1 CDS rplK NC_009778.1 3637395 3637823 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(3637395..3637823) Cronobacter sakazakii ATCC BAA-894 5550325 YP_001439737.1 CDS nusG NC_009778.1 3637974 3638519 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(3637974..3638519) Cronobacter sakazakii ATCC BAA-894 5550150 YP_001439738.1 CDS secE NC_009778.1 3638521 3638919 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(3638521..3638919) Cronobacter sakazakii ATCC BAA-894 5550333 YP_001439739.1 CDS ESA_03699 NC_009778.1 3639139 3640323 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3639139..3640323) Cronobacter sakazakii ATCC BAA-894 5550264 YP_001439740.1 CDS ESA_03704 NC_009778.1 3641416 3642372 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3641416..3642372 Cronobacter sakazakii ATCC BAA-894 5550275 YP_001439741.1 CDS ESA_03705 NC_009778.1 3642409 3643371 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(3642409..3643371) Cronobacter sakazakii ATCC BAA-894 5552016 YP_001439743.1 CDS hemG NC_009778.1 3649963 3650496 R catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase complement(3649963..3650496) Cronobacter sakazakii ATCC BAA-894 5550138 YP_001439744.1 CDS ESA_03711 NC_009778.1 3650507 3651958 R KEGG: shn:Shewana3_0031 1.1e-77 potassium uptake protein, TrkH family K00961; COG: COG0168 Trk-type K+ transport systems, membrane components; Psort location: plasma membrane, score: 23; potassium transporter complement(3650507..3651958) Cronobacter sakazakii ATCC BAA-894 5552334 YP_001439745.1 CDS ESA_03712 NC_009778.1 3651998 3652609 R KEGG: eci:UTI89_C4433 4.6e-79 yigZ; hypothetical protein K00560; COG: COG1739 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3651998..3652609) Cronobacter sakazakii ATCC BAA-894 5552241 YP_001439746.1 CDS ESA_03713 NC_009778.1 3652609 3653940 R catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase complement(3652609..3653940) Cronobacter sakazakii ATCC BAA-894 5552286 YP_001439747.1 CDS fadB NC_009778.1 3654130 3656319 D includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 3654130..3656319 Cronobacter sakazakii ATCC BAA-894 5552271 YP_001439748.1 CDS fadA NC_009778.1 3656330 3657493 D FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 3656330..3657493 Cronobacter sakazakii ATCC BAA-894 5552278 YP_001439749.1 CDS ESA_03716 NC_009778.1 3657629 3657976 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3657629..3657976 Cronobacter sakazakii ATCC BAA-894 5552289 YP_001439750.1 CDS fre NC_009778.1 3658004 3658705 R NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase complement(3658004..3658705) Cronobacter sakazakii ATCC BAA-894 5552258 YP_001439751.1 CDS ESA_03718 NC_009778.1 3658751 3660235 R catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate decarboxylase complement(3658751..3660235) Cronobacter sakazakii ATCC BAA-894 5552245 YP_001439752.1 CDS rfaH NC_009778.1 3660353 3660907 D COG: COG0250 Transcription antiterminator; Psort location: mitochondrial, score: 23; transcriptional activator RfaH 3660353..3660907 Cronobacter sakazakii ATCC BAA-894 5552183 YP_001439753.1 CDS ESA_03720 NC_009778.1 3660955 3661287 R KEGG: fal:FRAAL1637 0.0012 alcohol dehydrogenase K00001; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3660955..3661287) Cronobacter sakazakii ATCC BAA-894 5552184 YP_001439754.1 CDS ESA_03721 NC_009778.1 3661411 3662268 R magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD complement(3661411..3662268) Cronobacter sakazakii ATCC BAA-894 5552207 YP_001439755.1 CDS ESA_03722 NC_009778.1 3662243 3663004 R with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC complement(3662243..3663004) Cronobacter sakazakii ATCC BAA-894 5552239 YP_001439756.1 CDS ESA_03723 NC_009778.1 3663006 3663566 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(3663006..3663566) Cronobacter sakazakii ATCC BAA-894 5550657 YP_001439757.1 CDS ESA_03724 NC_009778.1 3663570 3663833 R COG: COG1826 Sec-independent protein secretion pathway components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3663570..3663833) Cronobacter sakazakii ATCC BAA-894 5550156 YP_001439758.1 CDS ubiB NC_009778.1 3663912 3665552 R an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB complement(3663912..3665552) Cronobacter sakazakii ATCC BAA-894 5548470 YP_001439759.1 CDS ESA_03726 NC_009778.1 3665549 3666136 R COG: COG3165 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3665549..3666136) Cronobacter sakazakii ATCC BAA-894 5549929 YP_001439760.1 CDS ubiE NC_009778.1 3666166 3666921 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(3666166..3666921) Cronobacter sakazakii ATCC BAA-894 5550241 YP_001439761.1 CDS ESA_03728 NC_009778.1 3667011 3668447 R YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC complement(3667011..3668447) Cronobacter sakazakii ATCC BAA-894 5549309 YP_001439762.1 CDS ESA_03729 NC_009778.1 3668590 3669345 R catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase complement(3668590..3669345) Cronobacter sakazakii ATCC BAA-894 5548991 YP_001439763.1 CDS ESA_03730 NC_009778.1 3669605 3670423 D KEGG: stm:STM3967 3.3e-124 dlhH; putative dienelactone hydrolase family K01061; COG: COG0412 Dienelactone hydrolase and related enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein 3669605..3670423 Cronobacter sakazakii ATCC BAA-894 5552321 YP_001439764.1 CDS ESA_03731 NC_009778.1 3670842 3673103 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase complement(3670842..3673103) Cronobacter sakazakii ATCC BAA-894 5548354 YP_001439765.1 CDS ESA_03732 NC_009778.1 3673428 3674381 D KEGG: shn:Shewana3_3435 1.9e-14 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 3673428..3674381 Cronobacter sakazakii ATCC BAA-894 5548418 YP_001439766.1 CDS ESA_03733 NC_009778.1 3674269 3675201 R COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(3674269..3675201) Cronobacter sakazakii ATCC BAA-894 5549978 YP_001439767.1 CDS ESA_03734 NC_009778.1 3675280 3676080 R purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase complement(3675280..3676080) Cronobacter sakazakii ATCC BAA-894 5548925 YP_001439768.1 CDS ESA_03735 NC_009778.1 3676130 3677122 R lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 complement(3676130..3677122) Cronobacter sakazakii ATCC BAA-894 5549971 YP_001439769.1 CDS rhtB NC_009778.1 3677232 3677852 D COG: COG1280 Putative threonine efflux protein; Psort location: endoplasmic reticulum, score: 9; homoserine/homoserine lactone efflux protein 3677232..3677852 Cronobacter sakazakii ATCC BAA-894 5548392 YP_001439770.1 CDS ESA_03737 NC_009778.1 3677853 3678473 R COG: COG1280 Putative threonine efflux protein; Psort location: endoplasmic reticulum, score: 9; threonine efflux system complement(3677853..3678473) Cronobacter sakazakii ATCC BAA-894 5548252 YP_001439771.1 CDS ESA_03738 NC_009778.1 3678533 3680362 R functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ complement(3678533..3680362) Cronobacter sakazakii ATCC BAA-894 5548506 YP_001439772.1 CDS ESA_03739 NC_009778.1 3680430 3681299 R catalyzes the hydrolysis of phosphatidylcholine; phospholipase A complement(3680430..3681299) Cronobacter sakazakii ATCC BAA-894 5548160 YP_001439773.1 CDS ESA_03740 NC_009778.1 3681447 3681950 D COG: COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; Psort location: cytoplasmic, score: 23; hypothetical protein 3681447..3681950 Cronobacter sakazakii ATCC BAA-894 5548154 YP_001439774.1 CDS ESA_03741 NC_009778.1 3682003 3682896 D COG: COG2962 Predicted permeases; Psort location: endoplasmic reticulum, score: 23; hypothetical protein 3682003..3682896 Cronobacter sakazakii ATCC BAA-894 5548282 YP_001439775.1 CDS ESA_03742 NC_009778.1 3683086 3683472 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3683086..3683472 Cronobacter sakazakii ATCC BAA-894 5549983 YP_001439776.1 CDS ESA_03743 NC_009778.1 3683541 3683936 D COG: NOG09851 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3683541..3683936 Cronobacter sakazakii ATCC BAA-894 5548256 YP_001439777.1 CDS ESA_03744 NC_009778.1 3683993 3684943 R responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA complement(3683993..3684943) Cronobacter sakazakii ATCC BAA-894 5548384 YP_001439778.1 CDS uvrD NC_009778.1 3685424 3687586 R unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II complement(3685424..3687586) Cronobacter sakazakii ATCC BAA-894 5551264 YP_001439779.1 CDS ESA_03746 NC_009778.1 3687726 3688442 R KEGG: bur:Bcep18194_B2556 2.5e-25 HAD-superfamily hydrolase, subfamily IA, variant 1 K01560; COG: COG1011 Predicted hydrolase (HAD superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein complement(3687726..3688442) Cronobacter sakazakii ATCC BAA-894 5548422 YP_001439780.1 CDS xerC NC_009778.1 3688442 3689347 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(3688442..3689347) Cronobacter sakazakii ATCC BAA-894 5548441 YP_001439781.1 CDS ESA_03748 NC_009778.1 3689344 3690048 R KEGG: azo:azo0595 1.0e-06 3',5'-cyclic-nucleotide phosphodiesterase K01120; COG: COG3159 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3689344..3690048) Cronobacter sakazakii ATCC BAA-894 5552257 YP_001439782.1 CDS dapF NC_009778.1 3690045 3690869 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(3690045..3690869) Cronobacter sakazakii ATCC BAA-894 5548340 YP_001439783.1 CDS ESA_03750 NC_009778.1 3690902 3691105 R COG: COG5567 Predicted small periplasmic lipoprotein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3690902..3691105) Cronobacter sakazakii ATCC BAA-894 5548306 YP_001439784.1 CDS cyaY NC_009778.1 3691272 3691592 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 3691272..3691592 Cronobacter sakazakii ATCC BAA-894 5552322 YP_001439785.1 CDS cyaA NC_009778.1 3691593 3694139 R catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase complement(3691593..3694139) Cronobacter sakazakii ATCC BAA-894 5548448 YP_001439786.1 CDS hemC NC_009778.1 3694422 3695363 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 3694422..3695363 Cronobacter sakazakii ATCC BAA-894 5548134 YP_001439787.1 CDS hemD NC_009778.1 3695360 3696100 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 3695360..3696100 Cronobacter sakazakii ATCC BAA-894 5552471 YP_001439788.1 CDS ESA_03755 NC_009778.1 3696121 3697317 D KEGG: spt:SPA3777 6.6e-151 hemX; uroporphyrinogen III methylase K02496; COG: COG2959 Uncharacterized enzyme of heme biosynthesis; Psort location: nuclear, score: 23; putative uroporphyrinogen III C-methyltransferase 3696121..3697317 Cronobacter sakazakii ATCC BAA-894 5548121 YP_001439789.1 CDS ESA_03756 NC_009778.1 3697317 3698513 D COG: COG3071 Uncharacterized enzyme of heme biosynthesis; Psort location: endoplasmic reticulum, score: 9; putative protoheme IX biogenesis protein 3697317..3698513 Cronobacter sakazakii ATCC BAA-894 5548167 YP_001439790.1 CDS ESA_03758 NC_009778.1 3699083 3704665 R KEGG: ava:Ava_4160 4.1e-34 VCBS K01317; COG: COG5295 Autotransporter adhesin; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3699083..3704665) Cronobacter sakazakii ATCC BAA-894 5548229 YP_001439791.1 CDS ESA_03759 NC_009778.1 3705162 3705290 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3705162..3705290) Cronobacter sakazakii ATCC BAA-894 5548123 YP_001439792.1 CDS ESA_03764 NC_009778.1 3705824 3707209 R uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK complement(3705824..3707209) Cronobacter sakazakii ATCC BAA-894 5552145 YP_001439793.1 CDS ESA_03765 NC_009778.1 3707435 3708178 R KEGG: ecc:c4716 3.6e-111 wecG; probable UDP-N-acetyl-D-mannosaminuronic acid transferase K02852; COG: COG1922 Teichoic acid biosynthesis proteins; Psort location: cytoplasmic, score: 23; putative UDP-N-acetyl-D-mannosaminuronic acid transferase complement(3707435..3708178) Cronobacter sakazakii ATCC BAA-894 5548125 YP_001439794.1 CDS ESA_03766 NC_009778.1 3708191 3709555 R enterobacterial common antigen polymerase; putative common antigen polymerase complement(3708191..3709555) Cronobacter sakazakii ATCC BAA-894 5548280 YP_001439795.1 CDS ESA_03767 NC_009778.1 3709552 3710628 R catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase complement(3709552..3710628) Cronobacter sakazakii ATCC BAA-894 5548322 YP_001439796.1 CDS ESA_03768 NC_009778.1 3710625 3711875 R COG: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Psort location: plasma membrane, score: 23; hypothetical protein complement(3710625..3711875) Cronobacter sakazakii ATCC BAA-894 5548428 YP_001439797.1 CDS ESA_03769 NC_009778.1 3711877 3713007 R catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase complement(3711877..3713007) Cronobacter sakazakii ATCC BAA-894 5548269 YP_001439798.1 CDS ESA_03770 NC_009778.1 3713013 3713696 R KEGG: eci:UTI89_C4346 2.3e-70 rffC, rff, wecD, yifH; TDP-fucosamine acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; TDP-fucosamine acetyltransferase complement(3713013..3713696) Cronobacter sakazakii ATCC BAA-894 5548209 YP_001439799.1 CDS wecC NC_009778.1 3713718 3714980 R catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase complement(3713718..3714980) Cronobacter sakazakii ATCC BAA-894 5548144 YP_001439800.1 CDS ESA_03772 NC_009778.1 3714977 3716062 R KEGG: eci:UTI89_C4342 3.2e-167 rffE, yifF, nfrC, wecB; UDP-N-acetylglucosamine 2-epimerase K01791; COG: COG0381 UDP-N-acetylglucosamine 2-epimerase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3714977..3716062) Cronobacter sakazakii ATCC BAA-894 5552463 YP_001439801.1 CDS ESA_03773 NC_009778.1 3716165 3717214 R Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE complement(3716165..3717214) Cronobacter sakazakii ATCC BAA-894 5548172 YP_001439802.1 CDS ESA_03774 NC_009778.1 3717232 3718332 R KEGG: ssn:SSO_3956 2.6e-172 rfe; UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase K02851; COG: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; Psort location: plasma membrane, score: 23; hypothetical protein complement(3717232..3718332) Cronobacter sakazakii ATCC BAA-894 5548350 YP_001439803.1 CDS rho NC_009778.1 3718583 3719842 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(3718583..3719842) Cronobacter sakazakii ATCC BAA-894 5548379 YP_001439804.1 CDS trxA NC_009778.1 3720198 3720527 R KEGG: eci:UTI89_C4335 4.7e-54 trxA; THIoredoxin 1 K03671; COG: COG0526 Thiol-disulfide isomerase and THIoredoxins; Psort location: cytoplasmic, score: 23; thioredoxin complement(3720198..3720527) Cronobacter sakazakii ATCC BAA-894 5548113 YP_001439805.1 CDS ESA_03777 NC_009778.1 3720645 3721910 D enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 3720645..3721910 Cronobacter sakazakii ATCC BAA-894 5548349 YP_001439806.1 CDS ESA_03778 NC_009778.1 3721916 3723400 D catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 3721916..3723400 Cronobacter sakazakii ATCC BAA-894 5548290 YP_001439807.1 CDS ESA_03779 NC_009778.1 3723465 3725486 R single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep complement(3723465..3725486) Cronobacter sakazakii ATCC BAA-894 5548440 YP_001439808.1 CDS ESA_03780 NC_009778.1 3725605 3725886 D KEGG: spt:SPA3749 1.8e-45 ppiC; peptidyl-prolyl cis-trans isomerase C K03769; COG: COG0760 Parvulin-like peptidyl-prolyl isomerase; Psort location: cytoplasmic, score: 23; hypothetical protein 3725605..3725886 Cronobacter sakazakii ATCC BAA-894 5548232 YP_001439809.1 CDS ESA_03781 NC_009778.1 3726211 3727686 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(3726211..3727686) Cronobacter sakazakii ATCC BAA-894 5548278 YP_001439810.1 CDS ESA_03782 NC_009778.1 3727717 3727854 D Psort location: cytoplasmic, score: 23; hypothetical protein 3727717..3727854 Cronobacter sakazakii ATCC BAA-894 5548222 YP_001439811.1 CDS ESA_03783 NC_009778.1 3727968 3728840 D participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 3727968..3728840 Cronobacter sakazakii ATCC BAA-894 5548198 YP_001439812.1 CDS ESA_03784 NC_009778.1 3728837 3730384 R threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase complement(3728837..3730384) Cronobacter sakazakii ATCC BAA-894 5548647 YP_001439813.1 CDS ESA_03785 NC_009778.1 3730384 3732192 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(3730384..3732192) Cronobacter sakazakii ATCC BAA-894 5548787 YP_001439814.1 CDS ESA_03786 NC_009778.1 3732299 3733228 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(3732299..3733228) Cronobacter sakazakii ATCC BAA-894 5548339 YP_001439815.1 CDS ilvM NC_009778.1 3733249 3733506 R KEGG: ypn:YPN_0067 1.4e-29 acetolactate synthase isozyme II small subunit K01653; COG: COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit; Psort location: cytoplasmic, score: 23; acetolactate synthase 2 regulatory subunit complement(3733249..3733506) Cronobacter sakazakii ATCC BAA-894 5548781 YP_001439816.1 CDS ESA_03788 NC_009778.1 3733503 3735149 R catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit complement(3733503..3735149) Cronobacter sakazakii ATCC BAA-894 5548325 YP_001439817.1 CDS ESA_03789 NC_009778.1 3735618 3737258 D KEGG: eci:UTI89_C4322 3.7e-212 yifB; putative 2-component regulator K07391; COG: COG0606 Predicted ATPase with chaperone activity; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3735618..3737258 Cronobacter sakazakii ATCC BAA-894 5548460 YP_001439818.1 CDS ESA_03790 NC_009778.1 3737337 3737675 R COG: COG3085 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3737337..3737675) Cronobacter sakazakii ATCC BAA-894 5548753 YP_001439819.1 CDS ESA_03791 NC_009778.1 3737783 3738616 D Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 3737783..3738616 Cronobacter sakazakii ATCC BAA-894 5548106 YP_001439821.1 CDS ESA_03799 NC_009778.1 3744369 3745130 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(3744369..3745130) Cronobacter sakazakii ATCC BAA-894 5548342 YP_001439822.1 CDS btuB NC_009778.1 3745165 3747030 R involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter complement(3745165..3747030) Cronobacter sakazakii ATCC BAA-894 5548373 YP_001439823.1 CDS ESA_03801 NC_009778.1 3747387 3748490 D catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 3747387..3748490 Cronobacter sakazakii ATCC BAA-894 5548225 YP_001439824.1 CDS ESA_03802 NC_009778.1 3748518 3748877 R COG: NOG10261 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3748518..3748877) Cronobacter sakazakii ATCC BAA-894 5548181 YP_001439825.1 CDS ESA_03803 NC_009778.1 3748888 3749523 R negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR complement(3748888..3749523) Cronobacter sakazakii ATCC BAA-894 5548297 YP_001439826.1 CDS ESA_03804 NC_009778.1 3749693 3751120 D catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 3749693..3751120 Cronobacter sakazakii ATCC BAA-894 5552116 YP_001439827.1 CDS ESA_03805 NC_009778.1 3751103 3752020 R Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR complement(3751103..3752020) Cronobacter sakazakii ATCC BAA-894 5548331 YP_001439828.1 CDS ESA_03806 NC_009778.1 3752300 3753673 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(3752300..3753673) Cronobacter sakazakii ATCC BAA-894 5548543 YP_001439829.1 CDS ESA_03807 NC_009778.1 3753890 3755107 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(3753890..3755107) Cronobacter sakazakii ATCC BAA-894 5548188 YP_001439830.1 CDS ESA_03808 NC_009778.1 3755134 3755910 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(3755134..3755910) Cronobacter sakazakii ATCC BAA-894 5548632 YP_001439831.1 CDS argC NC_009778.1 3755925 3757061 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(3755925..3757061) Cronobacter sakazakii ATCC BAA-894 5548738 YP_001439832.1 CDS ESA_03810 NC_009778.1 3757116 3758261 D catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 3757116..3758261 Cronobacter sakazakii ATCC BAA-894 5548152 YP_001439833.1 CDS ESA_03811 NC_009778.1 3758919 3761531 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 3758919..3761531 Cronobacter sakazakii ATCC BAA-894 5548356 YP_001439834.1 CDS ESA_03812 NC_009778.1 3761598 3762752 R COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3761598..3762752) Cronobacter sakazakii ATCC BAA-894 5548482 YP_001439835.1 CDS ESA_03813 NC_009778.1 3762798 3765467 R COG: COG3188 P pilus assembly protein, porin PapC; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3762798..3765467) Cronobacter sakazakii ATCC BAA-894 5548615 YP_001439836.1 CDS ESA_03814 NC_009778.1 3765513 3766208 R COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3765513..3766208) Cronobacter sakazakii ATCC BAA-894 5548512 YP_001439837.1 CDS ESA_03815 NC_009778.1 3766261 3766827 R KEGG: bme:BMEII0148 0.0069 extracellular serine protease; COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3766261..3766827) Cronobacter sakazakii ATCC BAA-894 5551781 YP_001439838.1 CDS ESA_03816 NC_009778.1 3767453 3769111 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(3767453..3769111) Cronobacter sakazakii ATCC BAA-894 5548634 YP_001439839.1 CDS ESA_03817 NC_009778.1 3769385 3770674 R KEGG: bba:Bd3613 1.6e-19 sensory transduction histidine kinase; COG: COG2202 FOG: PAS/PAC domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3769385..3770674) Cronobacter sakazakii ATCC BAA-894 5548531 YP_001439840.1 CDS ESA_03818 NC_009778.1 3770734 3770886 D Psort location: cytoplasmic, score: 23; hypothetical protein 3770734..3770886 Cronobacter sakazakii ATCC BAA-894 5548433 YP_001439841.1 CDS ESA_03819 NC_009778.1 3770742 3770858 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3770742..3770858) Cronobacter sakazakii ATCC BAA-894 5548617 YP_001439842.1 CDS metF NC_009778.1 3771021 3771926 R MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase complement(3771021..3771926) Cronobacter sakazakii ATCC BAA-894 5550843 YP_001439843.1 CDS metL NC_009778.1 3772228 3774660 R multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II complement(3772228..3774660) Cronobacter sakazakii ATCC BAA-894 5548122 YP_001439844.1 CDS ESA_03822 NC_009778.1 3774670 3775824 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(3774670..3775824) Cronobacter sakazakii ATCC BAA-894 5548183 YP_001439845.1 CDS ESA_03823 NC_009778.1 3776105 3776422 D when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 3776105..3776422 Cronobacter sakazakii ATCC BAA-894 5548124 YP_001439846.1 CDS rpmE NC_009778.1 3776515 3776727 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(3776515..3776727) Cronobacter sakazakii ATCC BAA-894 5548361 YP_001439847.1 CDS ESA_03825 NC_009778.1 3776931 3779126 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 3776931..3779126 Cronobacter sakazakii ATCC BAA-894 5548299 YP_001439848.1 CDS ESA_03826 NC_009778.1 3779317 3780318 D negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 3779317..3780318 Cronobacter sakazakii ATCC BAA-894 5552002 YP_001439849.1 CDS ESA_03827 NC_009778.1 3780510 3781442 D KEGG: rno:309804 4.3e-08 Cdc2l6_predicted; cell division cycle 2-like 6 (CDK8-like) (predicted) K02208; COG: COG3087 Cell division protein; Psort location: nuclear, score: 23; cell division protein FtsN 3780510..3781442 Cronobacter sakazakii ATCC BAA-894 5548309 YP_001439850.1 CDS ESA_03828 NC_009778.1 3781552 3782064 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 3781552..3782064 Cronobacter sakazakii ATCC BAA-894 5548119 YP_001439851.1 CDS hslU NC_009778.1 3782074 3783405 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 3782074..3783405 Cronobacter sakazakii ATCC BAA-894 5548352 YP_001439852.1 CDS ESA_03830 NC_009778.1 3783445 3783582 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3783445..3783582 Cronobacter sakazakii ATCC BAA-894 5548217 YP_001439853.1 CDS ESA_03831 NC_009778.1 3783579 3784511 D catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 3783579..3784511 Cronobacter sakazakii ATCC BAA-894 5552449 YP_001439854.1 CDS ESA_03832 NC_009778.1 3784604 3785089 D regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 3784604..3785089 Cronobacter sakazakii ATCC BAA-894 5549199 YP_001439855.1 CDS ESA_03833 NC_009778.1 3785140 3785379 R COG: COG3074 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3785140..3785379) Cronobacter sakazakii ATCC BAA-894 5548130 YP_001439856.1 CDS ESA_03834 NC_009778.1 3785815 3786663 D COG: COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3785815..3786663 Cronobacter sakazakii ATCC BAA-894 5550745 YP_001439857.1 CDS ESA_03835 NC_009778.1 3786682 3788199 D KEGG: sec:SC3975 6.5e-263 glpK; glycerol kinase K00864; COG: COG0554 Glycerol kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 3786682..3788199 Cronobacter sakazakii ATCC BAA-894 5548659 YP_001439858.1 CDS ESA_03836 NC_009778.1 3788328 3788690 D COG: NOG10267 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3788328..3788690 Cronobacter sakazakii ATCC BAA-894 5548803 YP_001439859.1 CDS ESA_03837 NC_009778.1 3788719 3789003 R COG: NOG17530 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3788719..3789003) Cronobacter sakazakii ATCC BAA-894 5552212 YP_001439860.1 CDS ESA_03838 NC_009778.1 3788993 3789313 R COG: COG4679 Phage-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3788993..3789313) Cronobacter sakazakii ATCC BAA-894 5548393 YP_001439861.1 CDS ESA_03839 NC_009778.1 3789693 3791372 D COG: COG1620 L-lactate permease; Psort location: plasma membrane, score: 23; L-lactate permease 3789693..3791372 Cronobacter sakazakii ATCC BAA-894 5548644 YP_001439862.1 CDS ESA_03840 NC_009778.1 3791369 3792157 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3791369..3792157 Cronobacter sakazakii ATCC BAA-894 5548550 YP_001439863.1 CDS lldD NC_009778.1 3792154 3793359 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3792154..3793359 Cronobacter sakazakii ATCC BAA-894 5548774 YP_001439864.1 CDS ESA_03842 NC_009778.1 3793522 3794199 R COG: COG2258 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3793522..3794199) Cronobacter sakazakii ATCC BAA-894 5548799 YP_001439865.1 CDS ESA_03843 NC_009778.1 3794270 3794905 R SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase complement(3794270..3794905) Cronobacter sakazakii ATCC BAA-894 5548511 YP_001439866.1 CDS ESA_03844 NC_009778.1 3795263 3796300 D transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 3795263..3796300 Cronobacter sakazakii ATCC BAA-894 5548548 YP_001439867.1 CDS ESA_03845 NC_009778.1 3796297 3797148 R KEGG: bli:BL05281 1.2e-09 adaA; methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3796297..3797148) Cronobacter sakazakii ATCC BAA-894 5548602 YP_001439868.1 CDS ESA_03846 NC_009778.1 3797220 3798008 R activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS complement(3797220..3798008) Cronobacter sakazakii ATCC BAA-894 5552451 YP_001439869.1 CDS ESA_03847 NC_009778.1 3798358 3799476 D KEGG: ecj:JW3875 6.5e-144 rhaB; rhamnulokinase K00848; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: cytoplasmic, score: 23; hypothetical protein 3798358..3799476 Cronobacter sakazakii ATCC BAA-894 5548586 YP_001439870.1 CDS ESA_03848 NC_009778.1 3799502 3799831 D KEGG: sec:SC3937 6.6e-32 rhaB; rhamnulokinase K00848; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: cytoplasmic, score: 23; hypothetical protein 3799502..3799831 Cronobacter sakazakii ATCC BAA-894 5548532 YP_001439871.1 CDS ESA_03849 NC_009778.1 3799828 3801084 D catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 3799828..3801084 Cronobacter sakazakii ATCC BAA-894 5548591 YP_001439872.1 CDS ESA_03850 NC_009778.1 3801094 3801918 D KEGG: eca:ECA0438 1.6e-117 rhaD; rhamnulose-1-phosphate aldolase K01629; COG: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Psort location: cytoplasmic, score: 23; rhamnulose-1-phosphate aldolase 3801094..3801918 Cronobacter sakazakii ATCC BAA-894 5548566 YP_001439873.1 CDS ESA_03851 NC_009778.1 3802216 3803364 D KEGG: sty:STY3830 1.3e-175 alcohol dehydrogenase K00001; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: cytoplasmic, score: 23; hypothetical protein 3802216..3803364 Cronobacter sakazakii ATCC BAA-894 5548598 YP_001439874.1 CDS ESA_03852 NC_009778.1 3803361 3803675 D KEGG: msm:MSMEG_0587 5.1e-09 rhaU; L-rhamnose 1-epimerase; COG: COG3254 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein 3803361..3803675 Cronobacter sakazakii ATCC BAA-894 5548626 YP_001439875.1 CDS lacY NC_009778.1 3803909 3805171 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(3803909..3805171) Cronobacter sakazakii ATCC BAA-894 5548569 YP_001439876.1 CDS ESA_03854 NC_009778.1 3805229 3807352 R KEGG: eca:ECA0754 2.2e-278 rafA; alpha-galactosidase K07407; COG: COG3345 Alpha-galactosidase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3805229..3807352) Cronobacter sakazakii ATCC BAA-894 5548606 YP_001439877.1 CDS ESA_03855 NC_009778.1 3807470 3808477 R COG: COG1609 Transcriptional regulators; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3807470..3808477) Cronobacter sakazakii ATCC BAA-894 5548546 YP_001439878.1 CDS ESA_03856 NC_009778.1 3808553 3809101 R KEGG: psp:PSPPH_2917 2.7e-08 DNA-binding protein K00517; COG: COG1396 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3808553..3809101) Cronobacter sakazakii ATCC BAA-894 5548589 YP_001439879.1 CDS ESA_03857 NC_009778.1 3809204 3809866 D COG: COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3809204..3809866 Cronobacter sakazakii ATCC BAA-894 5548522 YP_001439880.1 CDS ESA_03858 NC_009778.1 3809866 3810189 D COG: NOG19750 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3809866..3810189 Cronobacter sakazakii ATCC BAA-894 5548557 YP_001439881.1 CDS ESA_03859 NC_009778.1 3810242 3810451 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3810242..3810451) Cronobacter sakazakii ATCC BAA-894 5548537 YP_001439882.1 CDS ESA_03860 NC_009778.1 3810582 3811424 R involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein complement(3810582..3811424) Cronobacter sakazakii ATCC BAA-894 5548435 YP_001439883.1 CDS ESA_03861 NC_009778.1 3811590 3812177 D KEGG: ecc:c5624 3.8e-100 fdoG; formate dehydrogenase-O, major subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3811590..3812177 Cronobacter sakazakii ATCC BAA-894 5548520 YP_001439884.1 CDS ESA_03862 NC_009778.1 3812226 3814640 D KEGG: sty:STY3839 0. fdoG; formate dehydrogenase-O, major subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: cytoplasmic, score: 23; hypothetical protein 3812226..3814640 Cronobacter sakazakii ATCC BAA-894 5548783 YP_001439885.1 CDS ESA_03863 NC_009778.1 3814653 3815555 D KEGG: stm:STM4036 1.9e-162 fdoH; formate dehydrogenase-O, Fe-S subunit K00124; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: cytoplasmic, score: 23; hypothetical protein 3814653..3815555 Cronobacter sakazakii ATCC BAA-894 5548526 YP_001439886.1 CDS ESA_03864 NC_009778.1 3815552 3816187 D cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 3815552..3816187 Cronobacter sakazakii ATCC BAA-894 5548682 YP_001439887.1 CDS ESA_03865 NC_009778.1 3816184 3817113 D required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 3816184..3817113 Cronobacter sakazakii ATCC BAA-894 5548549 YP_001439888.1 CDS ESA_03866 NC_009778.1 3817187 3817477 R COG: COG2944 Predicted transcriptional regulator; Psort location: nuclear, score: 23; hypothetical protein complement(3817187..3817477) Cronobacter sakazakii ATCC BAA-894 5548529 YP_001439889.1 CDS ESA_03867 NC_009778.1 3817477 3817788 R COG: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3817477..3817788) Cronobacter sakazakii ATCC BAA-894 5548800 YP_001439890.1 CDS ESA_03868 NC_009778.1 3817963 3818787 R KEGG: bha:BH0394 3.7e-07 adaA; methylphosphotriester-DNA alkyltransferase (AraC/XylS family) K00567; COG: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3817963..3818787) Cronobacter sakazakii ATCC BAA-894 5548786 YP_001439891.1 CDS ESA_03869 NC_009778.1 3819048 3820451 D KEGG: eci:UTI89_C4210 4.6e-72 yicJ; hypothetical symporter YicJ K03292; COG: COG2211 Na+/melibiose symporter and related transporters; Psort location: plasma membrane, score: 23; hypothetical protein 3819048..3820451 Cronobacter sakazakii ATCC BAA-894 5548317 YP_001439892.1 CDS ESA_03870 NC_009778.1 3820463 3822430 D COG: COG3533 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 3820463..3822430 Cronobacter sakazakii ATCC BAA-894 5548576 YP_001439893.1 CDS ESA_03871 NC_009778.1 3822443 3823060 R COG: COG1280 Putative threonine efflux protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(3822443..3823060) Cronobacter sakazakii ATCC BAA-894 5548219 YP_001439894.1 CDS ESA_03872 NC_009778.1 3823193 3824068 D KEGG: fnu:FN1474 1.7e-40 N-acetylmannosamine kinase K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: cytoplasmic, score: 23; hypothetical protein 3823193..3824068 Cronobacter sakazakii ATCC BAA-894 5548333 YP_001439895.1 CDS ESA_03873 NC_009778.1 3824093 3825250 R KEGG: ecc:c4410 1.1e-155 yiaY; probable alcohol dehydrogenase K00001; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: cytoplasmic, score: 23; putative alcohol dehydrogenase complement(3824093..3825250) Cronobacter sakazakii ATCC BAA-894 5548630 YP_001439896.1 CDS ESA_03874 NC_009778.1 3825455 3827302 R KEGG: eci:UTI89_C4132 2.8e-246 selB; selenocysteine-specific elongation factor K03833; COG: COG3276 Selenocysteine-specific translation elongation factor; Psort location: cytoplasmic, score: 23; selenocysteinyl-tRNA-specific translation factor complement(3825455..3827302) Cronobacter sakazakii ATCC BAA-894 5550812 YP_001439897.1 CDS ESA_03875 NC_009778.1 3827299 3828690 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(3827299..3828690) Cronobacter sakazakii ATCC BAA-894 5550722 YP_001439898.1 CDS ESA_03876 NC_009778.1 3828786 3829394 R KEGG: eci:UTI89_C4134 1.2e-80 yibF; putative S-transferase K00799; COG: COG0625 glutathione S-transferase; Psort location: cytoplasmic, score: 23; putative glutathione S-transferase complement(3828786..3829394) Cronobacter sakazakii ATCC BAA-894 5548523 YP_001439899.1 CDS ESA_03877 NC_009778.1 3829915 3831834 D KEGG: stm:STM3685 0. mtlA; PTS family, mannitol-specific enzyme IIABC components K02798:K02799:K02800; COG: COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; Psort location: plasma membrane, score: 23; hypothetical protein 3829915..3831834 Cronobacter sakazakii ATCC BAA-894 5548551 YP_001439900.1 CDS ESA_03878 NC_009778.1 3832022 3833170 D KEGG: stm:STM3686 6.7e-174 mtlD; mannitol-1-phosphate dehydrogenase K00009; COG: COG0246 Mannitol-1-phosphate/altronate dehydrogenases; Psort location: cytoplasmic, score: 23; mannitol-1-phosphate 5-dehydrogenase 3832022..3833170 Cronobacter sakazakii ATCC BAA-894 5548780 YP_001439901.1 CDS mtlR NC_009778.1 3833219 3833758 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 3833219..3833758 Cronobacter sakazakii ATCC BAA-894 5548776 YP_001439902.1 CDS glpX NC_009778.1 3833871 3834881 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 3833871..3834881 Cronobacter sakazakii ATCC BAA-894 5548696 YP_001439903.1 CDS ESA_03881 NC_009778.1 3834975 3835721 D KEGG: ssn:SSO_4093 2.7e-115 fpr; ferredoxin-NADP reductase K00528; COG: COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Psort location: cytoplasmic, score: 23; ferredoxin-NADP reductase 3834975..3835721 Cronobacter sakazakii ATCC BAA-894 5548639 YP_001439904.1 CDS ESA_03882 NC_009778.1 3835722 3836141 R COG: COG3152 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3835722..3836141) Cronobacter sakazakii ATCC BAA-894 5548620 YP_001439905.1 CDS ESA_03883 NC_009778.1 3836159 3836314 D Psort location: cytoplasmic, score: 23; hypothetical protein 3836159..3836314 Cronobacter sakazakii ATCC BAA-894 5548746 YP_001439906.1 CDS ESA_03884 NC_009778.1 3836256 3836855 D COG: NOG06218 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3836256..3836855 Cronobacter sakazakii ATCC BAA-894 5548671 YP_001439907.1 CDS tpiA NC_009778.1 3836980 3837729 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 3836980..3837729 Cronobacter sakazakii ATCC BAA-894 5548677 YP_001439908.1 CDS ESA_03886 NC_009778.1 3837791 3838180 R COG: COG5435 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3837791..3838180) Cronobacter sakazakii ATCC BAA-894 5552298 YP_001439909.1 CDS ESA_03887 NC_009778.1 3838625 3839092 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3838625..3839092) Cronobacter sakazakii ATCC BAA-894 5548629 YP_001439910.1 CDS ESA_03888 NC_009778.1 3839414 3839632 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3839414..3839632) Cronobacter sakazakii ATCC BAA-894 5548611 YP_001439911.1 CDS ESA_03889 NC_009778.1 3839810 3840169 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3839810..3840169) Cronobacter sakazakii ATCC BAA-894 5552232 YP_001439912.1 CDS ESA_03890 NC_009778.1 3840417 3840833 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3840417..3840833) Cronobacter sakazakii ATCC BAA-894 5548665 YP_001439913.1 CDS ESA_03892 NC_009778.1 3841084 3841275 R COG: COG3209 Rhs family protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3841084..3841275) Cronobacter sakazakii ATCC BAA-894 5552246 YP_001439914.1 CDS ESA_03891 NC_009778.1 3841120 3841434 D Psort location: cytoplasmic, score: 23; hypothetical protein 3841120..3841434 Cronobacter sakazakii ATCC BAA-894 5552455 YP_001439915.1 CDS ESA_03893 NC_009778.1 3841502 3842044 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3841502..3842044) Cronobacter sakazakii ATCC BAA-894 5548637 YP_001439916.1 CDS ESA_03894 NC_009778.1 3842880 3843326 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3842880..3843326) Cronobacter sakazakii ATCC BAA-894 5548627 YP_001439917.1 CDS ESA_03895 NC_009778.1 3843777 3844238 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3843777..3844238) Cronobacter sakazakii ATCC BAA-894 5552237 YP_001439918.1 CDS ESA_03897 NC_009778.1 3844475 3844774 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3844475..3844774) Cronobacter sakazakii ATCC BAA-894 5548737 YP_001439919.1 CDS ESA_03896 NC_009778.1 3844656 3844790 D Psort location: nuclear, score: 23; hypothetical protein 3844656..3844790 Cronobacter sakazakii ATCC BAA-894 5548711 YP_001439920.1 CDS ESA_03898 NC_009778.1 3844891 3845421 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3844891..3845421) Cronobacter sakazakii ATCC BAA-894 5548757 YP_001439921.1 CDS ESA_03899 NC_009778.1 3845424 3846932 R KEGG: sph:MGAS10270_Spy0598 0.00014 streptodornase K01150; COG: COG3209 Rhs family protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3845424..3846932) Cronobacter sakazakii ATCC BAA-894 5548744 YP_001439922.1 CDS ESA_03900 NC_009778.1 3846942 3847103 D Psort location: cytoplasmic, score: 23; hypothetical protein 3846942..3847103 Cronobacter sakazakii ATCC BAA-894 5548668 YP_001439923.1 CDS ESA_03901 NC_009778.1 3846954 3847061 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3846954..3847061) Cronobacter sakazakii ATCC BAA-894 5548678 YP_001439924.1 CDS ESA_03902 NC_009778.1 3847163 3847792 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3847163..3847792) Cronobacter sakazakii ATCC BAA-894 5548723 YP_001439925.1 CDS ESA_03903 NC_009778.1 3847803 3852350 R COG: COG3209 Rhs family protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3847803..3852350) Cronobacter sakazakii ATCC BAA-894 5552400 YP_001439926.1 CDS ESA_03904 NC_009778.1 3852353 3852784 R COG: COG5435 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3852353..3852784) Cronobacter sakazakii ATCC BAA-894 5548756 YP_001439927.1 CDS ESA_03905 NC_009778.1 3852781 3854721 R COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3852781..3854721) Cronobacter sakazakii ATCC BAA-894 5548812 YP_001439928.1 CDS ESA_03907 NC_009778.1 3854770 3854901 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3854770..3854901) Cronobacter sakazakii ATCC BAA-894 5548775 YP_001439929.1 CDS ESA_03906 NC_009778.1 3854890 3855024 D Psort location: cytoplasmic, score: 23; hypothetical protein 3854890..3855024 Cronobacter sakazakii ATCC BAA-894 5548935 YP_001439930.1 CDS ESA_03908 NC_009778.1 3854983 3855147 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3854983..3855147) Cronobacter sakazakii ATCC BAA-894 5548688 YP_001439931.1 CDS ESA_03909 NC_009778.1 3855415 3855954 R Psort location: nuclear, score: 23; hypothetical protein complement(3855415..3855954) Cronobacter sakazakii ATCC BAA-894 5548993 YP_001439932.1 CDS ESA_03910 NC_009778.1 3856034 3856468 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3856034..3856468) Cronobacter sakazakii ATCC BAA-894 5552406 YP_001439933.1 CDS ESA_03911 NC_009778.1 3856761 3857075 R COG: COG3209 Rhs family protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3856761..3857075) Cronobacter sakazakii ATCC BAA-894 5548998 YP_001439934.1 CDS ESA_03912 NC_009778.1 3857271 3857813 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3857271..3857813) Cronobacter sakazakii ATCC BAA-894 5552316 YP_001439935.1 CDS ESA_03913 NC_009778.1 3857813 3861832 R KEGG: rpa:RPA3229 0.00054 adk; adenylate kinase K00939; COG: COG3209 Rhs family protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3857813..3861832) Cronobacter sakazakii ATCC BAA-894 5548805 YP_001439936.1 CDS ESA_03914 NC_009778.1 3862051 3862731 R KEGG: psp:PSPPH_1820 0.00019 ankyrin domain protein; COG: COG0666 FOG: Ankyrin repeat; Psort location: nuclear, score: 23; hypothetical protein complement(3862051..3862731) Cronobacter sakazakii ATCC BAA-894 5548831 YP_001439937.1 CDS ESA_03915 NC_009778.1 3862829 3864124 R KEGG: xcv:XCV3039 4.0e-16 putative phospholipase A1 K01058; COG: COG4104 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3862829..3864124) Cronobacter sakazakii ATCC BAA-894 5548985 YP_001439938.1 CDS ESA_03916 NC_009778.1 3864117 3865271 R COG: COG5351 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3864117..3865271) Cronobacter sakazakii ATCC BAA-894 5548867 YP_001439939.1 CDS ESA_03917 NC_009778.1 3865273 3867420 R KEGG: pfa:PFD0565c 2.9e-06 RNA helicase, putative K01509; COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3865273..3867420) Cronobacter sakazakii ATCC BAA-894 5552049 YP_001439940.1 CDS ESA_03918 NC_009778.1 3867552 3868313 R KEGG: dre:352910 1.3e-07 mib; mind bomb K01932; COG: COG0666 FOG: Ankyrin repeat; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3867552..3868313) Cronobacter sakazakii ATCC BAA-894 5548989 YP_001439941.1 CDS ESA_03919 NC_009778.1 3868310 3869740 R KEGG: xcv:XCV3039 6.4e-14 putative phospholipase A1 K01058; COG: COG4104 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3868310..3869740) Cronobacter sakazakii ATCC BAA-894 5548996 YP_001439942.1 CDS ESA_03920 NC_009778.1 3869865 3871298 R KEGG: bte:BTH_II0256 3.5e-79 serine/threonine protein kinase K00870; COG: COG0515 Serine/threonine protein kinase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3869865..3871298) Cronobacter sakazakii ATCC BAA-894 5550896 YP_001439943.1 CDS ESA_03921 NC_009778.1 3871329 3873944 R KEGG: bte:BTH_I2958 2.0e-238 ClpA/B type protease K01358; COG: COG0542 ATPases with chaperone activity, ATP-binding subunit; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3871329..3873944) Cronobacter sakazakii ATCC BAA-894 5548872 YP_001439944.1 CDS ESA_03922 NC_009778.1 3874161 3875204 R COG: COG3520 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3874161..3875204) Cronobacter sakazakii ATCC BAA-894 5548811 YP_001439945.1 CDS ESA_03923 NC_009778.1 3875201 3877072 R COG: COG3519 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3875201..3877072) Cronobacter sakazakii ATCC BAA-894 5548891 YP_001439946.1 CDS ESA_03924 NC_009778.1 3877075 3877647 R COG: COG3518 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(3877075..3877647) Cronobacter sakazakii ATCC BAA-894 5548853 YP_001439947.1 CDS ESA_03925 NC_009778.1 3877640 3878473 R COG: COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3877640..3878473) Cronobacter sakazakii ATCC BAA-894 5548829 YP_001439948.1 CDS ESA_03926 NC_009778.1 3878499 3879503 R COG: NOG10802 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3878499..3879503) Cronobacter sakazakii ATCC BAA-894 5548847 YP_001439949.1 CDS ESA_03927 NC_009778.1 3879522 3880316 R KEGG: tte:TTE1501 3.8e-20 ptc1; protein serine/threonine phosphatases K01090; COG: COG0631 Serine/threonine protein phosphatase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3879522..3880316) Cronobacter sakazakii ATCC BAA-894 5548845 YP_001439950.1 CDS ESA_03928 NC_009778.1 3880313 3882244 R KEGG: rno:85238 2.6e-07 Synj1; synaptojanin 1 K01099; COG: COG3456 Uncharacterized conserved protein, contains FHA domain; Psort location: nuclear, score: 23; hypothetical protein complement(3880313..3882244) Cronobacter sakazakii ATCC BAA-894 5548821 YP_001439951.1 CDS ESA_03929 NC_009778.1 3882344 3882757 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3882344..3882757) Cronobacter sakazakii ATCC BAA-894 5548910 YP_001439952.1 CDS ESA_03930 NC_009778.1 3882754 3883626 R COG: NOG13310 non supervised orthologous group; Psort location: vesicles of secretory system, score: 9; hypothetical protein complement(3882754..3883626) Cronobacter sakazakii ATCC BAA-894 5548911 YP_001439953.1 CDS ESA_03932 NC_009778.1 3883806 3884177 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3883806..3884177) Cronobacter sakazakii ATCC BAA-894 5548897 YP_001439954.1 CDS ESA_03931 NC_009778.1 3883894 3884232 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3883894..3884232 Cronobacter sakazakii ATCC BAA-894 5548886 YP_001439955.1 CDS ESA_03933 NC_009778.1 3884198 3884566 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3884198..3884566) Cronobacter sakazakii ATCC BAA-894 5548878 YP_001439956.1 CDS ESA_03934 NC_009778.1 3884614 3885096 R COG: COG3157 Hemolysin-coregulated protein (uncharacterized); Psort location: cytoplasmic, score: 23; hypothetical protein complement(3884614..3885096) Cronobacter sakazakii ATCC BAA-894 5548841 YP_001439957.1 CDS ESA_03935 NC_009778.1 3885353 3885847 R COG: NOG17434 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3885353..3885847) Cronobacter sakazakii ATCC BAA-894 5548836 YP_001439958.1 CDS ESA_03936 NC_009778.1 3885844 3886278 R COG: NOG22256 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(3885844..3886278) Cronobacter sakazakii ATCC BAA-894 5548828 YP_001439959.1 CDS ESA_03938 NC_009778.1 3886302 3886394 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3886302..3886394) Cronobacter sakazakii ATCC BAA-894 5548850 YP_001439960.1 CDS ESA_03937 NC_009778.1 3886324 3886482 D Psort location: cytoplasmic, score: 23; hypothetical protein 3886324..3886482 Cronobacter sakazakii ATCC BAA-894 5548874 YP_001439961.1 CDS ESA_03939 NC_009778.1 3886456 3886875 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3886456..3886875) Cronobacter sakazakii ATCC BAA-894 5549002 YP_001439962.1 CDS ESA_03941 NC_009778.1 3886942 3888441 R KEGG: bpm:BURPS1710b_A0534 1.7e-95 hypothetical protein K00356; COG: COG3517 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(3886942..3888441) Cronobacter sakazakii ATCC BAA-894 5548843 YP_001439963.1 CDS ESA_03940 NC_009778.1 3887380 3889032 D Psort location: mitochondrial, score: 23; hypothetical protein 3887380..3889032 Cronobacter sakazakii ATCC BAA-894 5548859 YP_001439964.1 CDS ESA_03942 NC_009778.1 3888445 3888981 R COG: COG3516 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3888445..3888981) Cronobacter sakazakii ATCC BAA-894 5548862 YP_001439965.1 CDS ESA_03943 NC_009778.1 3889045 3890067 R COG: COG3515 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3889045..3890067) Cronobacter sakazakii ATCC BAA-894 5548814 YP_001439966.1 CDS ESA_03944 NC_009778.1 3890077 3890787 R COG: COG3913 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3890077..3890787) Cronobacter sakazakii ATCC BAA-894 5548856 YP_001439967.1 CDS ESA_03945 NC_009778.1 3890804 3894424 R COG: COG3523 Uncharacterized protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3890804..3894424) Cronobacter sakazakii ATCC BAA-894 5548813 YP_001439968.1 CDS ESA_03946 NC_009778.1 3894426 3895661 R COG: COG1360 Flagellar motor protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3894426..3895661) Cronobacter sakazakii ATCC BAA-894 5551105 YP_001439969.1 CDS ESA_03947 NC_009778.1 3895679 3897022 R COG: COG3522 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3895679..3897022) Cronobacter sakazakii ATCC BAA-894 5552293 YP_001439970.1 CDS ESA_03948 NC_009778.1 3897047 3897553 R COG: COG3521 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3897047..3897553) Cronobacter sakazakii ATCC BAA-894 5548483 YP_001439971.1 CDS ESA_03949 NC_009778.1 3897578 3898072 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3897578..3898072) Cronobacter sakazakii ATCC BAA-894 5551229 YP_001439972.1 CDS ESA_03950 NC_009778.1 3899468 3899920 D KEGG: btk:BT9727_2623 2.5e-16 acetyltransferase, GNAT family K00680; COG: NOG22518 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 3899468..3899920 Cronobacter sakazakii ATCC BAA-894 5550888 YP_001439973.1 CDS emrD NC_009778.1 3900123 3901310 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 3900123..3901310 Cronobacter sakazakii ATCC BAA-894 5551121 YP_001439974.1 CDS ESA_03952 NC_009778.1 3901213 3902310 R KEGG: rba:RB5256 3.6e-07 cellulase K01179; COG: NOG14136 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3901213..3902310) Cronobacter sakazakii ATCC BAA-894 5548961 YP_001439975.1 CDS ESA_03953 NC_009778.1 3902381 3902776 D Psort location: nuclear, score: 23; hypothetical protein 3902381..3902776 Cronobacter sakazakii ATCC BAA-894 5549156 YP_001439976.1 CDS ESA_03954 NC_009778.1 3902384 3902725 R COG: NOG09782 non supervised orthologous group; Psort location: vacuolar, score: 9; hypothetical protein complement(3902384..3902725) Cronobacter sakazakii ATCC BAA-894 5548913 YP_001439977.1 CDS ESA_03955 NC_009778.1 3902715 3903098 R KEGG: cal:orf19.201 0.00014 CDC47; DNA helicase and DNA replication licensing factor K02210; COG: COG2149 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3902715..3903098) Cronobacter sakazakii ATCC BAA-894 5548927 YP_001439978.1 CDS ESA_03956 NC_009778.1 3903181 3904503 R KEGG: ece:Z5177 7.3e-216 putative 6-phospho-beta-glucosidase K01222; COG: COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3903181..3904503) Cronobacter sakazakii ATCC BAA-894 5548952 YP_001439979.1 CDS ESA_03957 NC_009778.1 3904500 3906116 R KEGG: ece:Z5178 2.1e-234 putative PTS component K02749:K02750; COG: COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; Psort location: plasma membrane, score: 23; hypothetical protein complement(3904500..3906116) Cronobacter sakazakii ATCC BAA-894 5548969 YP_001439980.1 CDS ESA_03958 NC_009778.1 3906338 3907054 D KEGG: btk:BT9727_3183 9.3e-26 transcriptional regulator, GntR family; COG: COG2188 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 3906338..3907054 Cronobacter sakazakii ATCC BAA-894 5548578 YP_001439981.1 CDS ESA_03959 NC_009778.1 3907115 3907600 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(3907115..3907600) Cronobacter sakazakii ATCC BAA-894 5548562 YP_001439982.1 CDS ESA_03960 NC_009778.1 3907712 3908128 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(3907712..3908128) Cronobacter sakazakii ATCC BAA-894 5548902 YP_001439983.1 CDS ESA_03961 NC_009778.1 3908232 3908399 D Psort location: mitochondrial, score: 23; hypothetical protein 3908232..3908399 Cronobacter sakazakii ATCC BAA-894 5548954 YP_001439984.1 CDS ESA_03962 NC_009778.1 3908433 3908759 D COG: COG5645 Predicted periplasmic lipoprotein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3908433..3908759 Cronobacter sakazakii ATCC BAA-894 5548863 YP_001439985.1 CDS ESA_03963 NC_009778.1 3908760 3910022 R KEGG: eci:UTI89_C4240 9.5e-159 yidR; hypothetical protein YidR; COG: NOG06296 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3908760..3910022) Cronobacter sakazakii ATCC BAA-894 5548973 YP_001439986.1 CDS ESA_03964 NC_009778.1 3910084 3911016 R KEGG: ypm:YP_2347 5.8e-72 ldhA2; putative D-isomer specific 2-hydroxyacid dehydrogenase family protein K00050; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3910084..3911016) Cronobacter sakazakii ATCC BAA-894 5548683 YP_001439987.1 CDS ESA_03965 NC_009778.1 3911013 3912332 R KEGG: bur:Bcep18194_A4604 0.00018 major facilitator superfamily (MFS_1) transporter and phospholipid/glycerol acyltransferase K00655; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(3911013..3912332) Cronobacter sakazakii ATCC BAA-894 5548880 YP_001439988.1 CDS ESA_03966 NC_009778.1 3912469 3913704 R KEGG: dre:30298 9.5e-06 jak2b; Janus kinase 2b K04447; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3912469..3913704) Cronobacter sakazakii ATCC BAA-894 5548865 YP_001439989.1 CDS ESA_03967 NC_009778.1 3914083 3915231 R KEGG: stm:STM3828 6.0e-189 dgoA; 2-oxo-3-deoxygalactonate 6-phosphate aldolase/galactonate dehydratase K01631:K01684; COG: COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Psort location: cytoplasmic, score: 23; galactonate dehydratase complement(3914083..3915231) Cronobacter sakazakii ATCC BAA-894 5548884 YP_001439990.1 CDS ESA_03968 NC_009778.1 3915228 3915845 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(3915228..3915845) Cronobacter sakazakii ATCC BAA-894 5552447 YP_001439991.1 CDS ESA_03969 NC_009778.1 3915829 3916713 R KEGG: ssn:SSO_3644 2.0e-110 dgoK; 2-oxo-3-deoxygalactonate kinase K00883; COG: COG3734 2-keto-3-deoxy-galactonokinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3915829..3916713) Cronobacter sakazakii ATCC BAA-894 5548904 YP_001439992.1 CDS ESA_03970 NC_009778.1 3916710 3917393 R COG: COG2186 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3916710..3917393) Cronobacter sakazakii ATCC BAA-894 5548905 YP_001439993.1 CDS ESA_03971 NC_009778.1 3917948 3918163 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3917948..3918163) Cronobacter sakazakii ATCC BAA-894 5548879 YP_001439994.1 CDS ESA_03972 NC_009778.1 3918169 3918981 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(3918169..3918981) Cronobacter sakazakii ATCC BAA-894 5548895 YP_001439995.1 CDS gyrB NC_009778.1 3919276 3921690 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(3919276..3921690) Cronobacter sakazakii ATCC BAA-894 5548938 YP_001439996.1 CDS recF NC_009778.1 3921719 3922792 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(3921719..3922792) Cronobacter sakazakii ATCC BAA-894 5548909 YP_001439997.1 CDS ESA_03975 NC_009778.1 3922949 3924049 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(3922949..3924049) Cronobacter sakazakii ATCC BAA-894 5549047 YP_001439998.1 CDS ESA_03976 NC_009778.1 3924054 3925370 R KEGG: shn:Shewana3_0009 7.3e-184 chromosomal replication initiator protein DnaA K00972; COG: COG0593 ATPase involved in DNA replication initiation; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3924054..3925370) Cronobacter sakazakii ATCC BAA-894 5548922 YP_001439999.1 CDS rnpA NC_009778.1 3926203 3926562 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 3926203..3926562 Cronobacter sakazakii ATCC BAA-894 5549131 YP_001440000.1 CDS ESA_03978 NC_009778.1 3926786 3928438 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3926786..3928438 Cronobacter sakazakii ATCC BAA-894 5548898 YP_001440001.1 CDS trmE NC_009778.1 3928539 3929903 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 3928539..3929903 Cronobacter sakazakii ATCC BAA-894 5549126 YP_001440002.1 CDS ESA_03980 NC_009778.1 3930734 3931132 R KEGG: pen:PSEEN0425 4.6e-08 glpE; THIosulfate sulfurtransferase (rhodanese) K01010; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: vesicles of secretory system, score: 9; hypothetical protein complement(3930734..3931132) Cronobacter sakazakii ATCC BAA-894 5549027 YP_001440003.1 CDS ESA_03981 NC_009778.1 3931192 3932106 R COG: NOG22885 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3931192..3932106) Cronobacter sakazakii ATCC BAA-894 5549117 YP_001440004.1 CDS ESA_03982 NC_009778.1 3932147 3932473 R COG: COG4392 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3932147..3932473) Cronobacter sakazakii ATCC BAA-894 5549015 YP_001440005.1 CDS ESA_03983 NC_009778.1 3932449 3933090 R COG: COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3932449..3933090) Cronobacter sakazakii ATCC BAA-894 5549097 YP_001440006.1 CDS ESA_03984 NC_009778.1 3933153 3933635 R KEGG: bcz:BCZK0234 4.6e-08 rimI; ribosomal-protein-alanine N-acetyltransferase K03789; COG: COG0456 Acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3933153..3933635) Cronobacter sakazakii ATCC BAA-894 5548930 YP_001440007.1 CDS ESA_03985 NC_009778.1 3933619 3934380 R COG: COG4340 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3933619..3934380) Cronobacter sakazakii ATCC BAA-894 5552095 YP_001440008.1 CDS ESA_03986 NC_009778.1 3934610 3935470 D COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 3934610..3935470 Cronobacter sakazakii ATCC BAA-894 5548984 YP_001440009.1 CDS ESA_03987 NC_009778.1 3935745 3936230 R Psort location: mitochondrial, score: 23; hypothetical protein complement(3935745..3936230) Cronobacter sakazakii ATCC BAA-894 5548972 YP_001440010.1 CDS ESA_03988 NC_009778.1 3936231 3936434 D COG: COG2091 Phosphopantetheinyl transferase; Psort location: nuclear, score: 23; hypothetical protein 3936231..3936434 Cronobacter sakazakii ATCC BAA-894 5549133 YP_001440011.1 CDS ESA_03989 NC_009778.1 3936459 3937028 D KEGG: eci:UTI89_C4266 2.1e-83 yieF; hypothetical protein; COG: COG0431 Predicted flavoprotein; Psort location: cytoplasmic, score: 23; hypothetical protein 3936459..3937028 Cronobacter sakazakii ATCC BAA-894 5549206 YP_001440012.1 CDS ESA_03990 NC_009778.1 3937061 3938398 R KEGG: bcz:BCZK0244 1.1e-88 guanine-hypoxanTHIne permease; xanTHIne/uracil permease family protein K06901; COG: COG2252 Permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(3937061..3938398) Cronobacter sakazakii ATCC BAA-894 5549175 YP_001440013.1 CDS ESA_03991 NC_009778.1 3938568 3939233 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 3938568..3939233 Cronobacter sakazakii ATCC BAA-894 5549200 YP_001440014.1 CDS ESA_03992 NC_009778.1 3939582 3940724 R KEGG: eci:UTI89_C4270 2.7e-138 yieL; putative xylanase K07214; COG: COG2382 Enterochelin esterase and related enzymes; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(3939582..3940724) Cronobacter sakazakii ATCC BAA-894 5549014 YP_001440015.1 CDS ESA_03993 NC_009778.1 3940867 3941592 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(3940867..3941592) Cronobacter sakazakii ATCC BAA-894 5549071 YP_001440016.1 CDS pstB NC_009778.1 3941651 3942424 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(3941651..3942424) Cronobacter sakazakii ATCC BAA-894 5549128 YP_001440017.1 CDS pstA NC_009778.1 3942475 3943365 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(3942475..3943365) Cronobacter sakazakii ATCC BAA-894 5549111 YP_001440018.1 CDS pstC NC_009778.1 3943365 3944324 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(3943365..3944324) Cronobacter sakazakii ATCC BAA-894 5549187 YP_001440019.1 CDS ESA_03997 NC_009778.1 3944464 3945504 R KEGG: mst:Msp_0343 2.4e-08 pstS; PstS K02040; COG: COG0226 ABC-type phosphate transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; phosphate ABC transporter periplasmic substrate-binding protein PstS complement(3944464..3945504) Cronobacter sakazakii ATCC BAA-894 5549088 YP_001440020.1 CDS ESA_03998 NC_009778.1 3945703 3946029 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3945703..3946029 Cronobacter sakazakii ATCC BAA-894 5549038 YP_001440021.1 CDS ESA_04000 NC_009778.1 3946069 3946689 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(3946069..3946689) Cronobacter sakazakii ATCC BAA-894 5549211 YP_001440022.1 CDS ESA_03999 NC_009778.1 3946327 3946428 D Psort location: nuclear, score: 23; hypothetical protein 3946327..3946428 Cronobacter sakazakii ATCC BAA-894 5549122 YP_001440023.1 CDS ESA_04001 NC_009778.1 3946769 3948598 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(3946769..3948598) Cronobacter sakazakii ATCC BAA-894 5549084 YP_001440024.1 CDS glmU NC_009778.1 3948826 3950181 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(3948826..3950181) Cronobacter sakazakii ATCC BAA-894 5549021 YP_001440025.1 CDS ESA_04004 NC_009778.1 3950296 3950457 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(3950296..3950457) Cronobacter sakazakii ATCC BAA-894 5549230 YP_001440026.1 CDS ESA_04003 NC_009778.1 3950437 3950982 D Psort location: cytoplasmic, score: 23; hypothetical protein 3950437..3950982 Cronobacter sakazakii ATCC BAA-894 5549033 YP_001440027.1 CDS atpC NC_009778.1 3950539 3950958 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(3950539..3950958) Cronobacter sakazakii ATCC BAA-894 5549048 YP_001440028.1 CDS ESA_04006 NC_009778.1 3950979 3952361 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(3950979..3952361) Cronobacter sakazakii ATCC BAA-894 5549101 YP_001440029.1 CDS ESA_04007 NC_009778.1 3952388 3953251 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(3952388..3953251) Cronobacter sakazakii ATCC BAA-894 5549059 YP_001440030.1 CDS ESA_04008 NC_009778.1 3953302 3954843 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(3953302..3954843) Cronobacter sakazakii ATCC BAA-894 5549079 YP_001440031.1 CDS ESA_04009 NC_009778.1 3954856 3955389 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(3954856..3955389) Cronobacter sakazakii ATCC BAA-894 5549060 YP_001440032.1 CDS ESA_04010 NC_009778.1 3955404 3955874 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(3955404..3955874) Cronobacter sakazakii ATCC BAA-894 5549123 YP_001440033.1 CDS ESA_04011 NC_009778.1 3955939 3956178 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(3955939..3956178) Cronobacter sakazakii ATCC BAA-894 5549087 YP_001440034.1 CDS ESA_04012 NC_009778.1 3956229 3957047 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(3956229..3957047) Cronobacter sakazakii ATCC BAA-894 5549204 YP_001440035.1 CDS ESA_04013 NC_009778.1 3957056 3957436 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(3957056..3957436) Cronobacter sakazakii ATCC BAA-894 5548871 YP_001440036.1 CDS gidB NC_009778.1 3958046 3958669 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(3958046..3958669) Cronobacter sakazakii ATCC BAA-894 5548600 YP_001440037.1 CDS ESA_04015 NC_009778.1 3958726 3960615 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(3958726..3960615) Cronobacter sakazakii ATCC BAA-894 5548603 YP_001440038.1 CDS ESA_04016 NC_009778.1 3960996 3961436 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3960996..3961436) Cronobacter sakazakii ATCC BAA-894 5548609 YP_001440039.1 CDS ESA_04017 NC_009778.1 3961526 3961984 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(3961526..3961984) Cronobacter sakazakii ATCC BAA-894 5548822 YP_001440040.1 CDS ESA_04018 NC_009778.1 3962138 3963130 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 3962138..3963130 Cronobacter sakazakii ATCC BAA-894 5548920 YP_001440041.1 CDS yieM NC_009778.1 3963132 3964583 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(3963132..3964583) Cronobacter sakazakii ATCC BAA-894 5549069 YP_001440042.1 CDS ESA_04020 NC_009778.1 3964577 3966076 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(3964577..3966076) Cronobacter sakazakii ATCC BAA-894 5549091 YP_001440043.1 CDS trkD NC_009778.1 3966297 3968168 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 3966297..3968168 Cronobacter sakazakii ATCC BAA-894 5549248 YP_001440044.1 CDS ESA_04022 NC_009778.1 3968349 3968780 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 3968349..3968780 Cronobacter sakazakii ATCC BAA-894 5549615 YP_001440045.1 CDS ESA_04023 NC_009778.1 3968788 3970293 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 3968788..3970293 Cronobacter sakazakii ATCC BAA-894 5549522 YP_001440046.1 CDS rbsC NC_009778.1 3970301 3971266 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease protein 3970301..3971266 Cronobacter sakazakii ATCC BAA-894 5549533 YP_001440047.1 CDS ESA_04025 NC_009778.1 3971293 3972180 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 3971293..3972180 Cronobacter sakazakii ATCC BAA-894 5550965 YP_001440048.1 CDS ESA_04026 NC_009778.1 3972246 3973175 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 3972246..3973175 Cronobacter sakazakii ATCC BAA-894 5550928 YP_001440049.1 CDS ESA_04027 NC_009778.1 3973191 3974174 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 3973191..3974174 Cronobacter sakazakii ATCC BAA-894 5550979 YP_001440050.1 CDS ESA_04028 NC_009778.1 3974171 3975565 R KEGG: sgl:SG1466 3.6e-08 dethiobiotinsynthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(3974171..3975565) Cronobacter sakazakii ATCC BAA-894 5550798 YP_001440051.1 CDS ESA_04029 NC_009778.1 3975579 3976280 R KEGG: reh:H16_A3019 0.00028 hutC; histidine utilization repressor; COG: COG2186 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3975579..3976280) Cronobacter sakazakii ATCC BAA-894 5551011 YP_001440052.1 CDS ESA_04033 NC_009778.1 3981926 3982459 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(3981926..3982459) Cronobacter sakazakii ATCC BAA-894 5550993 YP_001440053.1 CDS mobA NC_009778.1 3982459 3983046 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(3982459..3983046) Cronobacter sakazakii ATCC BAA-894 5550925 YP_001440054.1 CDS ESA_04035 NC_009778.1 3983101 3983373 D COG: COG3084 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 3983101..3983373 Cronobacter sakazakii ATCC BAA-894 5551037 YP_001440055.1 CDS ESA_04036 NC_009778.1 3983450 3984436 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 3983450..3984436 Cronobacter sakazakii ATCC BAA-894 5551029 YP_001440056.1 CDS ESA_04037 NC_009778.1 3984461 3985087 D KEGG: bci:BCI_0257 9.4e-49 dsbA; THIol:disulfide interchange protein DsbA K01829; COG: COG0526 Thiol-disulfide isomerase and THIoredoxins; Psort location: extracellular, including cell wall, score: 9; periplasmic protein disulfide isomerase I 3984461..3985087 Cronobacter sakazakii ATCC BAA-894 5550951 YP_001440057.1 CDS ESA_04038 NC_009778.1 3985114 3986022 R KEGG: eci:UTI89_C4450 1.9e-137 yihG; hypothetical protein YihG K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: mitochondrial, score: 23; putative acyltransferase complement(3985114..3986022) Cronobacter sakazakii ATCC BAA-894 5551066 YP_001440058.1 CDS ESA_04039 NC_009778.1 3986319 3986444 R Psort location: nuclear, score: 23; hypothetical protein complement(3986319..3986444) Cronobacter sakazakii ATCC BAA-894 5551013 YP_001440059.1 CDS ESA_04040 NC_009778.1 3986452 3989235 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 3986452..3989235 Cronobacter sakazakii ATCC BAA-894 5551082 YP_001440060.1 CDS engB NC_009778.1 3989538 3990206 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(3989538..3990206) Cronobacter sakazakii ATCC BAA-894 5551111 YP_001440061.1 CDS ESA_04044 NC_009778.1 3990764 3991294 D KEGG: bld:BLi03964 0.0033 rpoE; RNA polymerase (delta subunit); RBL01619 K03048; COG: COG3078 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 3990764..3991294 Cronobacter sakazakii ATCC BAA-894 5551136 YP_001440062.1 CDS ESA_04045 NC_009778.1 3991479 3992852 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3991479..3992852 Cronobacter sakazakii ATCC BAA-894 5551174 YP_001440063.1 CDS glnG NC_009778.1 3993113 3994522 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(3993113..3994522) Cronobacter sakazakii ATCC BAA-894 5551160 YP_001440064.1 CDS glnL NC_009778.1 3994531 3995580 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(3994531..3995580) Cronobacter sakazakii ATCC BAA-894 5551088 YP_001440065.1 CDS glnA NC_009778.1 3995779 3997188 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(3995779..3997188) Cronobacter sakazakii ATCC BAA-894 5551159 YP_001440066.1 CDS ESA_04049 NC_009778.1 3997567 3999390 D KEGG: eci:UTI89_C4460 0. typA, bipA, yihK, yjhK; putative GTP-binding factor K06207; COG: COG1217 Predicted membrane GTPase involved in stress response; Psort location: cytoplasmic, score: 23; GTP-binding protein 3997567..3999390 Cronobacter sakazakii ATCC BAA-894 5549223 YP_001440067.1 CDS ompL NC_009778.1 3999475 4000161 R porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L complement(3999475..4000161) Cronobacter sakazakii ATCC BAA-894 5551196 YP_001440068.1 CDS ESA_04051 NC_009778.1 4000236 4001666 R KEGG: eci:UTI89_C4210 3.8e-45 yicJ; hypothetical symporter YicJ K03292; COG: COG2211 Na+/melibiose symporter and related transporters; Psort location: plasma membrane, score: 23; hypothetical protein complement(4000236..4001666) Cronobacter sakazakii ATCC BAA-894 5551255 YP_001440069.1 CDS ESA_04052 NC_009778.1 4001715 4003121 R KEGG: eci:UTI89_C4210 8.7e-46 yicJ; hypothetical symporter YicJ K03292; COG: COG2211 Na+/melibiose symporter and related transporters; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4001715..4003121) Cronobacter sakazakii ATCC BAA-894 5551270 YP_001440070.1 CDS ESA_04053 NC_009778.1 4003154 4004026 R COG: COG0730 Predicted permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(4003154..4004026) Cronobacter sakazakii ATCC BAA-894 5551179 YP_001440071.1 CDS ESA_04054 NC_009778.1 4004039 4006069 R KEGG: lic:LIC11117 2.7e-129 malZ; alpha-glucosidase K01187; COG: COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Psort location: cytoplasmic, score: 23; alpha-glucosidase complement(4004039..4006069) Cronobacter sakazakii ATCC BAA-894 5551195 YP_001440072.1 CDS ESA_04055 NC_009778.1 4006119 4006985 R KEGG: eco:b3879 2.8e-79 yihR; predicted aldose-1-epimerase K01785; COG: COG2017 Galactose mutarotase and related enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4006119..4006985) Cronobacter sakazakii ATCC BAA-894 5551225 YP_001440073.1 CDS ESA_04056 NC_009778.1 4007014 4008255 R KEGG: eco:b3880 2.3e-205 yihS; predicted glucosamine isomerase; COG: COG2942 N-acyl-D-glucosamine 2-epimerase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4007014..4008255) Cronobacter sakazakii ATCC BAA-894 5551307 YP_001440074.1 CDS ESA_04057 NC_009778.1 4008270 4009145 R KEGG: eco:b3881 1.7e-120 yihT; predicted aldolase; COG: COG3684 Tagatose-1,6-bisphosphate aldolase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4008270..4009145) Cronobacter sakazakii ATCC BAA-894 5551292 YP_001440075.1 CDS ESA_04058 NC_009778.1 4009170 4010069 R KEGG: ece:Z5420 1.4e-123 yihU; putative dehydrogenase K08318; COG: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4009170..4010069) Cronobacter sakazakii ATCC BAA-894 5551291 YP_001440076.1 CDS ESA_04059 NC_009778.1 4010218 4011180 D KEGG: eci:UTI89_C4462 3.4e-99 yihV; hypothetical sugar kinase YihV K00846; COG: COG0524 Sugar kinases, ribokinase family; Psort location: cytoplasmic, score: 23; hypothetical protein 4010218..4011180 Cronobacter sakazakii ATCC BAA-894 5551287 YP_001440077.1 CDS ESA_04060 NC_009778.1 4011196 4012023 D COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4011196..4012023 Cronobacter sakazakii ATCC BAA-894 5551371 YP_001440078.1 CDS ESA_04061 NC_009778.1 4012133 4012732 D KEGG: xtr:448759 4.4e-11 ephx2; epoxide hydrolase 2, cytoplasmic K08726; COG: COG1011 Predicted hydrolase (HAD superfamily); Psort location: cytoplasmic, score: 23; phosphatase 4012133..4012732 Cronobacter sakazakii ATCC BAA-894 5551299 YP_001440079.1 CDS rbn NC_009778.1 4012726 4013595 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4012726..4013595 Cronobacter sakazakii ATCC BAA-894 5551403 YP_001440080.1 CDS ESA_04063 NC_009778.1 4013592 4014029 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4013592..4014029 Cronobacter sakazakii ATCC BAA-894 5551318 YP_001440081.1 CDS ESA_04064 NC_009778.1 4014026 4015015 D KEGG: eci:UTI89_C4472 5.7e-161 yiiD; putative acetyltransferase K00633; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein 4014026..4015015 Cronobacter sakazakii ATCC BAA-894 5551361 YP_001440082.1 CDS ESA_04065 NC_009778.1 4015312 4016994 R COG: NOG06061 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4015312..4016994) Cronobacter sakazakii ATCC BAA-894 5551411 YP_001440083.1 CDS ESA_04066 NC_009778.1 4017116 4018522 R KEGG: hpa:HPAG1_1114 0.00065 hypothetical protein K00760; COG: COG2233 XanTHIne/uracil permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(4017116..4018522) Cronobacter sakazakii ATCC BAA-894 5551335 YP_001440084.1 CDS ESA_04067 NC_009778.1 4018787 4019362 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4018787..4019362) Cronobacter sakazakii ATCC BAA-894 5551438 YP_001440085.1 CDS ESA_04068 NC_009778.1 4019420 4019980 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4019420..4019980) Cronobacter sakazakii ATCC BAA-894 5551363 YP_001440086.1 CDS ESA_04069 NC_009778.1 4020677 4021240 R KEGG: ava:Ava_4160 0.0044 VCBS K01317; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4020677..4021240) Cronobacter sakazakii ATCC BAA-894 5551426 YP_001440087.1 CDS ESA_04070 NC_009778.1 4021359 4022333 R COG: NOG06200 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4021359..4022333) Cronobacter sakazakii ATCC BAA-894 5551351 YP_001440088.1 CDS ESA_04071 NC_009778.1 4022339 4024801 R COG: COG3188 P pilus assembly protein, porin PapC; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4022339..4024801) Cronobacter sakazakii ATCC BAA-894 5551505 YP_001440089.1 CDS ESA_04072 NC_009778.1 4024815 4025576 R COG: COG3121 P pilus assembly protein, chaperone PapD; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4024815..4025576) Cronobacter sakazakii ATCC BAA-894 5551450 YP_001440090.1 CDS ESA_04073 NC_009778.1 4025607 4026197 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4025607..4026197) Cronobacter sakazakii ATCC BAA-894 5551470 YP_001440091.1 CDS ESA_04074 NC_009778.1 4026706 4028787 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(4026706..4028787) Cronobacter sakazakii ATCC BAA-894 5551479 YP_001440092.1 CDS ESA_04075 NC_009778.1 4028791 4029480 R specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase complement(4028791..4029480) Cronobacter sakazakii ATCC BAA-894 5551412 YP_001440093.1 CDS ESA_04076 NC_009778.1 4029485 4031605 R KEGG: spt:SPA3594 0. spoT; Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; CG Site No. 156 K01139; COG: COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; Psort location: cytoplasmic, score: 23; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase complement(4029485..4031605) Cronobacter sakazakii ATCC BAA-894 5551514 YP_001440094.1 CDS rpoZ NC_009778.1 4031625 4031900 R promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(4031625..4031900) Cronobacter sakazakii ATCC BAA-894 5551502 YP_001440095.1 CDS gmk NC_009778.1 4031955 4032578 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(4031955..4032578) Cronobacter sakazakii ATCC BAA-894 5551522 YP_001440096.1 CDS ligB NC_009778.1 4032836 4034521 D this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4032836..4034521 Cronobacter sakazakii ATCC BAA-894 5551512 YP_001440097.1 CDS ESA_04080 NC_009778.1 4034551 4035168 R COG: COG2860 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4034551..4035168) Cronobacter sakazakii ATCC BAA-894 5551563 YP_001440098.1 CDS ESA_04081 NC_009778.1 4035405 4036433 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4035405..4036433) Cronobacter sakazakii ATCC BAA-894 5549420 YP_001440099.1 CDS ESA_04082 NC_009778.1 4037105 4037707 D Psort location: nuclear, score: 23; hypothetical protein 4037105..4037707 Cronobacter sakazakii ATCC BAA-894 5551546 YP_001440100.1 CDS ESA_04083 NC_009778.1 4037760 4038137 R KEGG: pac:PPA1226 0.0037 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790; COG: COG1396 Predicted transcriptional regulators; Psort location: nuclear, score: 23; hypothetical protein complement(4037760..4038137) Cronobacter sakazakii ATCC BAA-894 5551585 YP_001440101.1 CDS ESA_04084 NC_009778.1 4039090 4039812 D Psort location: nuclear, score: 23; hypothetical protein 4039090..4039812 Cronobacter sakazakii ATCC BAA-894 5551385 YP_001440102.1 CDS ESA_04085 NC_009778.1 4041045 4042367 R Psort location: cytoskeletal, score: 9; hypothetical protein complement(4041045..4042367) Cronobacter sakazakii ATCC BAA-894 5551580 YP_001440103.1 CDS ESA_04086 NC_009778.1 4042368 4042793 R Psort location: nuclear, score: 23; hypothetical protein complement(4042368..4042793) Cronobacter sakazakii ATCC BAA-894 5551635 YP_001440104.1 CDS ESA_04087 NC_009778.1 4042971 4044233 R COG: COG0582 Integrase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4042971..4044233) Cronobacter sakazakii ATCC BAA-894 5551562 YP_001440105.1 CDS ESA_04088 NC_009778.1 4044425 4045288 R COG: COG1561 Uncharacterized stress-induced protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4044425..4045288) Cronobacter sakazakii ATCC BAA-894 5551673 YP_001440106.1 CDS ESA_04089 NC_009778.1 4045495 4046130 D KEGG: sty:STY4060 1.6e-101 rph; RNase PH K00989; COG: COG0689 RNase PH; Psort location: cytoplasmic, score: 23; hypothetical protein 4045495..4046130 Cronobacter sakazakii ATCC BAA-894 5551684 YP_001440107.1 CDS pyrE NC_009778.1 4046195 4046836 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4046195..4046836 Cronobacter sakazakii ATCC BAA-894 5551665 YP_001440108.1 CDS slmA NC_009778.1 4046888 4047484 R FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein complement(4046888..4047484) Cronobacter sakazakii ATCC BAA-894 5551639 YP_001440109.1 CDS dut NC_009778.1 4047610 4048068 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(4047610..4048068) Cronobacter sakazakii ATCC BAA-894 5551657 YP_001440110.1 CDS ESA_04093 NC_009778.1 4048046 4049257 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(4048046..4049257) Cronobacter sakazakii ATCC BAA-894 5551621 YP_001440111.1 CDS ESA_04094 NC_009778.1 4049326 4050093 D COG: COG2003 DNA repair proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 4049326..4050093 Cronobacter sakazakii ATCC BAA-894 5551611 YP_001440112.1 CDS rpmG NC_009778.1 4050565 4050732 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4050565..4050732 Cronobacter sakazakii ATCC BAA-894 5551800 YP_001440113.1 CDS ESA_04096 NC_009778.1 4050846 4051655 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4050846..4051655 Cronobacter sakazakii ATCC BAA-894 5551695 YP_001440114.1 CDS coaD NC_009778.1 4051656 4052135 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(4051656..4052135) Cronobacter sakazakii ATCC BAA-894 5551655 YP_001440115.1 CDS ESA_04098 NC_009778.1 4052140 4052907 R KEGG: sgl:SG2204 2.6e-92 lipopolysaccharide glycosyltransferase; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: mitochondrial, score: 23; hypothetical protein complement(4052140..4052907) Cronobacter sakazakii ATCC BAA-894 5551834 YP_001440116.1 CDS ESA_04099 NC_009778.1 4052907 4054226 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(4052907..4054226) Cronobacter sakazakii ATCC BAA-894 5551861 YP_001440117.1 CDS ESA_04100 NC_009778.1 4054359 4055993 R KEGG: hwa:HQ3540A 1.1e-05 aslA; probable arylsulfatase K01130; COG: COG2194 Predicted membrane-associated, metal-dependent hydrolase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4054359..4055993) Cronobacter sakazakii ATCC BAA-894 5551823 YP_001440118.1 CDS ESA_04101 NC_009778.1 4056016 4056987 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4056016..4056987) Cronobacter sakazakii ATCC BAA-894 5551796 YP_001440119.1 CDS ESA_04102 NC_009778.1 4056987 4057979 R KEGG: plu:plu4290 1.0e-122 unnamed protein product; similar to glycosyltransferase; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: cytoplasmic, score: 23; putative glycosyl transferase complement(4056987..4057979) Cronobacter sakazakii ATCC BAA-894 5551910 YP_001440120.1 CDS ESA_04103 NC_009778.1 4058139 4059428 R Psort location: plasma membrane, score: 23; hypothetical protein complement(4058139..4059428) Cronobacter sakazakii ATCC BAA-894 5551795 YP_001440121.1 CDS ESA_04104 NC_009778.1 4059646 4060824 D KEGG: azo:azo2322 9.7e-31 glycosyltransferase; COG: COG0438 Glycosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 4059646..4060824 Cronobacter sakazakii ATCC BAA-894 5551875 YP_001440122.1 CDS ESA_04105 NC_009778.1 4060803 4061912 R KEGG: ava:Ava_1122 6.3e-27 glycosyl transferase, group 1 K00703; COG: COG0438 Glycosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4060803..4061912) Cronobacter sakazakii ATCC BAA-894 5551877 YP_001440123.1 CDS ESA_04106 NC_009778.1 4061909 4063012 R KEGG: dar:Daro_0152 3.0e-91 lipopolysaccharide heptosyltransferase III, putative K02849; COG: COG0859 ADP-heptose:LPS heptosyltransferase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4061909..4063012) Cronobacter sakazakii ATCC BAA-894 5550308 YP_001440124.1 CDS ESA_04107 NC_009778.1 4063005 4064006 R KEGG: ece:Z5048 2.3e-141 rfaC; heptosyl transferase I; lipopolysaccharide core biosynthesis K02841; COG: COG0859 ADP-heptose:LPS heptosyltransferase; Psort location: cytoplasmic, score: 23; ADP-heptose:LPS heptosyl transferase I complement(4063005..4064006) Cronobacter sakazakii ATCC BAA-894 5552021 YP_001440125.1 CDS ESA_04108 NC_009778.1 4064010 4065056 R catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II complement(4064010..4065056) Cronobacter sakazakii ATCC BAA-894 5551899 YP_001440126.1 CDS rfaD NC_009778.1 4065069 4066001 R catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-mannoheptose-6-epimerase complement(4065069..4066001) Cronobacter sakazakii ATCC BAA-894 5552061 YP_001440127.1 CDS ESA_04110 NC_009778.1 4066230 4067426 D catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 4066230..4067426 Cronobacter sakazakii ATCC BAA-894 5552110 YP_001440128.1 CDS tdh NC_009778.1 4067436 4068461 D converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4067436..4068461 Cronobacter sakazakii ATCC BAA-894 5552143 YP_001440129.1 CDS ESA_04112 NC_009778.1 4068989 4069789 D KEGG: dar:Daro_3929 2.4e-27 glycosyl transferase, family 2; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4068989..4069789 Cronobacter sakazakii ATCC BAA-894 5551981 YP_001440130.1 CDS ESA_04113 NC_009778.1 4069821 4070762 R COG: COG2861 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(4069821..4070762) Cronobacter sakazakii ATCC BAA-894 5552066 YP_001440131.1 CDS ESA_04114 NC_009778.1 4070766 4072049 R KEGG: cya:CYA_1627 3.4e-28 peptidase, M23B family; COG: COG4942 Membrane-bound metallopeptidase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4070766..4072049) Cronobacter sakazakii ATCC BAA-894 5552089 YP_001440132.1 CDS ESA_04115 NC_009778.1 4072059 4073606 R catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase complement(4072059..4073606) Cronobacter sakazakii ATCC BAA-894 5552163 YP_001440133.1 CDS ESA_04116 NC_009778.1 4073850 4074281 D KEGG: pha:PSHAa0367 1.0e-26 rhodanese sulfur transferase K01010; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: cytoplasmic, score: 23; hypothetical protein 4073850..4074281 Cronobacter sakazakii ATCC BAA-894 5549676 YP_001440134.1 CDS ESA_04117 NC_009778.1 4074302 4074553 D KEGG: eci:UTI89_C4152 1.7e-35 grxC; glutaredoxin 3 K03676; COG: COG0695 Glutaredoxin and related proteins; Psort location: cytoplasmic, score: 23; glutaredoxin 3 4074302..4074553 Cronobacter sakazakii ATCC BAA-894 5549658 YP_001440135.1 CDS ESA_04118 NC_009778.1 4074553 4075077 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4074553..4075077 Cronobacter sakazakii ATCC BAA-894 5549641 YP_001440136.1 CDS gpsA NC_009778.1 4075077 4076096 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4075077..4076096 Cronobacter sakazakii ATCC BAA-894 5549582 YP_001440137.1 CDS cysE NC_009778.1 4076119 4076994 D catalyzes the O-acetylation of serine; serine acetyltransferase 4076119..4076994 Cronobacter sakazakii ATCC BAA-894 5549565 YP_001440138.1 CDS ESA_04121 NC_009778.1 4077058 4077531 R member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA/rRNA methyltransferase YibK complement(4077058..4077531) Cronobacter sakazakii ATCC BAA-894 5549486 YP_001440139.1 CDS cpxA NC_009778.1 4077634 4079007 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4077634..4079007) Cronobacter sakazakii ATCC BAA-894 5549631 YP_001440140.1 CDS ESA_04123 NC_009778.1 4079004 4079702 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4079004..4079702) Cronobacter sakazakii ATCC BAA-894 5549721 YP_001440141.1 CDS cpxP NC_009778.1 4079851 4080360 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4079851..4080360 Cronobacter sakazakii ATCC BAA-894 5549634 YP_001440142.1 CDS ESA_04125 NC_009778.1 4080407 4080541 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4080407..4080541 Cronobacter sakazakii ATCC BAA-894 5549589 YP_001440143.1 CDS fieF NC_009778.1 4080538 4081440 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4080538..4081440 Cronobacter sakazakii ATCC BAA-894 5549487 YP_001440144.1 CDS ESA_04127 NC_009778.1 4081630 4082592 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4081630..4082592 Cronobacter sakazakii ATCC BAA-894 5549443 YP_001440145.1 CDS ESA_04128 NC_009778.1 4082759 4083748 D COG: COG1613 ABC-type sulfate transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; sulfate transporter subunit 4082759..4083748 Cronobacter sakazakii ATCC BAA-894 5549639 YP_001440146.1 CDS ESA_04129 NC_009778.1 4083853 4084620 D KEGG: spt:SPA3907 5.6e-83 cdh; CDP-diglyceride hydrolase K01521; COG: COG2134 CDP-diacylglycerol pyrophosphatase; Psort location: extracellular, including cell wall, score: 9; CDP-diacylglycerol pyrophosphatase 4083853..4084620 Cronobacter sakazakii ATCC BAA-894 5549581 YP_001440147.1 CDS ESA_04130 NC_009778.1 4084679 4085983 D COG: COG0471 Di- and tricarboxylate transporters; Psort location: plasma membrane, score: 23; hypothetical protein 4084679..4085983 Cronobacter sakazakii ATCC BAA-894 5549558 YP_001440148.1 CDS ESA_04131 NC_009778.1 4086007 4086399 D Psort location: cytoplasmic, score: 23; hypothetical protein 4086007..4086399 Cronobacter sakazakii ATCC BAA-894 5549609 YP_001440149.1 CDS ESA_04132 NC_009778.1 4086384 4086797 R KEGG: gbe:GbCGDNIH1_1243 4.1e-16 urate oxidase K00365; COG: COG2351 Transthyretin-like protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4086384..4086797) Cronobacter sakazakii ATCC BAA-894 5549564 YP_001440150.1 CDS ESA_04134 NC_009778.1 4086794 4086928 R Psort location: nuclear, score: 23; hypothetical protein complement(4086794..4086928) Cronobacter sakazakii ATCC BAA-894 5551240 YP_001440151.1 CDS ESA_04133 NC_009778.1 4086927 4087607 D induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 4086927..4087607 Cronobacter sakazakii ATCC BAA-894 5549422 YP_001440152.1 CDS ESA_04135 NC_009778.1 4087600 4088961 D KEGG: sty:STY1127 8.5e-119 copS; histidine kinase K07644; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4087600..4088961 Cronobacter sakazakii ATCC BAA-894 5551554 YP_001440153.1 CDS ESA_04136 NC_009778.1 4088962 4089651 R COG: COG1266 Predicted metal-dependent membrane protease; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4088962..4089651) Cronobacter sakazakii ATCC BAA-894 5549442 YP_001440154.1 CDS ESA_04137 NC_009778.1 4089741 4090145 R KEGG: azo:azo0951 0.00024 conserved hypothetical phosphomannose protein K01809; COG: COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4089741..4090145) Cronobacter sakazakii ATCC BAA-894 5549645 YP_001440155.1 CDS ESA_04138 NC_009778.1 4090227 4091255 R KEGG: eci:UTI89_C1599 1.5e-41 hypothetical protein YcjY; COG: COG1073 Hydrolases of the alpha/beta superfamily; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4090227..4091255) Cronobacter sakazakii ATCC BAA-894 5550847 YP_001440156.1 CDS ESA_04139 NC_009778.1 4091307 4092353 R KEGG: eci:UTI89_C0359 1.3e-163 yahK; hypothetical zinc-type alcohol dehydrogenase-like protein YahK K00001; COG: COG1064 Zn-dependent alcohol dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4091307..4092353) Cronobacter sakazakii ATCC BAA-894 5549025 YP_001440157.1 CDS ESA_04140 NC_009778.1 4092388 4093617 R KEGG: tfu:Tfu_2783 0.0010 thymidylate kinase K00943; COG: COG2814 Arabinose efflux permease; Psort location: plasma membrane, score: 23; hypothetical protein complement(4092388..4093617) Cronobacter sakazakii ATCC BAA-894 5550838 YP_001440158.1 CDS ESA_04141 NC_009778.1 4093875 4094777 D KEGG: shn:Shewana3_3435 8.4e-08 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 4093875..4094777 Cronobacter sakazakii ATCC BAA-894 5550790 YP_001440159.1 CDS ESA_04142 NC_009778.1 4094787 4095836 R KEGG: sat:SYN_02803 4.2e-25 glycosyltransferase K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4094787..4095836) Cronobacter sakazakii ATCC BAA-894 5550845 YP_001440160.1 CDS ESA_04144 NC_009778.1 4095847 4096023 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4095847..4096023) Cronobacter sakazakii ATCC BAA-894 5550839 YP_001440161.1 CDS ESA_04143 NC_009778.1 4096022 4096600 D KEGG: ava:Ava_C0128 5.7e-58 ferredoxin K00190; COG: COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; Psort location: cytoplasmic, score: 23; hypothetical protein 4096022..4096600 Cronobacter sakazakii ATCC BAA-894 5550808 YP_001440162.1 CDS ESA_04145 NC_009778.1 4096597 4097550 D KEGG: eco:b0285 1.0e-136 yagS; putative oxidoreductase, FAD-binding domain K00087; COG: COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; Psort location: cytoplasmic, score: 23; hypothetical protein 4096597..4097550 Cronobacter sakazakii ATCC BAA-894 5550840 YP_001440163.1 CDS ESA_04146 NC_009778.1 4097550 4099748 D KEGG: ecj:JW0278 0. yagR; predicted oxidoreductase with molybdenum-binding domain K00087; COG: COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; Psort location: cytoplasmic, score: 23; hypothetical protein 4097550..4099748 Cronobacter sakazakii ATCC BAA-894 5550801 YP_001440164.1 CDS ESA_04147 NC_009778.1 4099819 4100754 D KEGG: aci:ACIAD2466 0.00022 putative xanTHIne dehydrogenase protein; putative xanTHIne dehydrogenase accessory factor (XdhC) K00087; COG: COG1975 XanTHIne and CO dehydrogenases maturation factor, XdhC/CoxF family; Psort location: cytoplasmic, score: 23; hypothetical protein 4099819..4100754 Cronobacter sakazakii ATCC BAA-894 5550820 YP_001440165.1 CDS ESA_04148 NC_009778.1 4100754 4101302 D KEGG: hma:pNG7236 5.4e-14 glmU; UDP-N-acetylglucosamine pyrophosphorylase K00972; COG: COG2068 Uncharacterized MobA-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein 4100754..4101302 Cronobacter sakazakii ATCC BAA-894 5550817 YP_001440166.1 CDS ESA_04149 NC_009778.1 4101363 4102280 R KEGG: ret:RHE_PC00204 3.0e-107 probable oxidoreductase protein, aldo-keto aldolase family; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein complement(4101363..4102280) Cronobacter sakazakii ATCC BAA-894 5550616 YP_001440167.1 CDS ESA_04150 NC_009778.1 4102306 4102923 D COG: NOG18230 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 4102306..4102923 Cronobacter sakazakii ATCC BAA-894 5550811 YP_001440168.1 CDS ESA_04151 NC_009778.1 4103218 4103640 D KEGG: eci:UTI89_C0121 1.5e-05 usp; uropathogenic specific protein K01150; COG: COG3157 Hemolysin-coregulated protein (uncharacterized); Psort location: cytoplasmic, score: 23; hypothetical protein 4103218..4103640 Cronobacter sakazakii ATCC BAA-894 5550813 YP_001440169.1 CDS ESA_04152 NC_009778.1 4104173 4104634 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4104173..4104634 Cronobacter sakazakii ATCC BAA-894 5550782 YP_001440170.1 CDS ESA_04153 NC_009778.1 4105040 4106443 D may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter 4105040..4106443 Cronobacter sakazakii ATCC BAA-894 5550780 YP_001440171.1 CDS ESA_04154 NC_009778.1 4106447 4108771 D catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI 4106447..4108771 Cronobacter sakazakii ATCC BAA-894 5550769 YP_001440172.1 CDS avtA NC_009778.1 4108820 4110118 R transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase complement(4108820..4110118) Cronobacter sakazakii ATCC BAA-894 5550762 YP_001440173.1 CDS malS NC_009778.1 4110250 4112421 R periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase precursor complement(4110250..4112421) Cronobacter sakazakii ATCC BAA-894 5550775 YP_001440174.1 CDS ESA_04157 NC_009778.1 4112849 4113418 D COG: COG2992 Uncharacterized FlgJ-related protein; Psort location: nuclear, score: 23; hypothetical protein 4112849..4113418 Cronobacter sakazakii ATCC BAA-894 5550750 YP_001440175.1 CDS ESA_04158 NC_009778.1 4113563 4114741 R KEGG: bcz:BCZK2914 1.3e-10 adaA; methylphosphotriester-DNA alkyltransferase K00567; COG: COG1609 Transcriptional regulators; Psort location: cytoskeletal, score: 9; hypothetical protein complement(4113563..4114741) Cronobacter sakazakii ATCC BAA-894 5550754 YP_001440176.1 CDS ESA_04159 NC_009778.1 4114840 4116030 R KEGG: msm:MSMEG_1706 1.2e-66 xylose transport system permease protein XylH; COG: COG4214 ABC-type xylose transport system, permease component; Psort location: plasma membrane, score: 23; hypothetical protein complement(4114840..4116030) Cronobacter sakazakii ATCC BAA-894 5550709 YP_001440177.1 CDS ESA_04160 NC_009778.1 4116008 4117549 R with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit complement(4116008..4117549) Cronobacter sakazakii ATCC BAA-894 5550728 YP_001440178.1 CDS xylF NC_009778.1 4117617 4118609 R periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF complement(4117617..4118609) Cronobacter sakazakii ATCC BAA-894 5550735 YP_001440179.1 CDS ESA_04162 NC_009778.1 4118992 4120314 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4118992..4120314 Cronobacter sakazakii ATCC BAA-894 5550724 YP_001440180.1 CDS ESA_04163 NC_009778.1 4120360 4121814 D KEGG: eci:UTI89_C4105 1.1e-212 xylB; xylulose kinase K00854; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: cytoplasmic, score: 23; hypothetical protein 4120360..4121814 Cronobacter sakazakii ATCC BAA-894 5550715 YP_001440181.1 CDS ESA_04164 NC_009778.1 4121937 4122479 D KEGG: ret:RHE_PF00312 1.2e-39 probable isochorismatase protein K05993; COG: COG1335 Amidases related to nicotinamidase; Psort location: mitochondrial, score: 23; hypothetical protein 4121937..4122479 Cronobacter sakazakii ATCC BAA-894 5550686 YP_001440182.1 CDS ESA_04165 NC_009778.1 4122476 4123396 D KEGG: bpm:BURPS1710b_A2214 7.2e-19 ftrA; transcriptional activator FtrA K00356; COG: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4122476..4123396 Cronobacter sakazakii ATCC BAA-894 5550671 YP_001440183.1 CDS ESA_04166 NC_009778.1 4123389 4124546 R KEGG: bba:Bd3365 0.0094 lspA; signal peptidase II K03101; COG: COG3274 Uncharacterized protein conserved in bacteria; Psort location: plasma membrane, score: 23; hypothetical protein complement(4123389..4124546) Cronobacter sakazakii ATCC BAA-894 5550723 YP_001440184.1 CDS ESA_04167 NC_009778.1 4124569 4124880 D COG: NOG10996 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4124569..4124880 Cronobacter sakazakii ATCC BAA-894 5550705 YP_001440185.1 CDS glyQ NC_009778.1 4124999 4125910 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4124999..4125910 Cronobacter sakazakii ATCC BAA-894 5550701 YP_001440186.1 CDS ESA_04170 NC_009778.1 4125227 4127176 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4125227..4127176) Cronobacter sakazakii ATCC BAA-894 5550694 YP_001440187.1 CDS glyS NC_009778.1 4125920 4127989 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4125920..4127989 Cronobacter sakazakii ATCC BAA-894 5550584 YP_001440188.1 CDS ESA_04171 NC_009778.1 4128593 4128886 R KEGG: mma:MM1160 0.0050 nucleotidyltransferase; COG: COG2944 Predicted transcriptional regulator; Psort location: nuclear, score: 23; putative transcriptional regulator complement(4128593..4128886) Cronobacter sakazakii ATCC BAA-894 5550696 YP_001440189.1 CDS ESA_04172 NC_009778.1 4129051 4129149 D Psort location: cytoplasmic, score: 23; hypothetical protein 4129051..4129149 Cronobacter sakazakii ATCC BAA-894 5550691 YP_001440190.1 CDS ESA_04173 NC_009778.1 4129069 4129362 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4129069..4129362) Cronobacter sakazakii ATCC BAA-894 5550674 YP_001440191.1 CDS ESA_04174 NC_009778.1 4129837 4130568 D COG: NOG06217 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 4129837..4130568 Cronobacter sakazakii ATCC BAA-894 5550627 YP_001440192.1 CDS ESA_04175 NC_009778.1 4130633 4131607 R KEGG: ece:Z4978 1.9e-144 yiaE; putative dehydrogenase K00090; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4130633..4131607) Cronobacter sakazakii ATCC BAA-894 5550656 YP_001440193.1 CDS ESA_04176 NC_009778.1 4131678 4132916 R KEGG: pca:Pcar_2776 0.0015 2-acyl-glycerophospho-ethanolamine acyltransferase K05939:K01909; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(4131678..4132916) Cronobacter sakazakii ATCC BAA-894 5550655 YP_001440194.1 CDS ESA_04177 NC_009778.1 4133125 4134066 R KEGG: bur:Bcep18194_A5029 6.7e-103 sugar kinase, ribokinase family K00874; COG: COG0524 Sugar kinases, ribokinase family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4133125..4134066) Cronobacter sakazakii ATCC BAA-894 5550651 YP_001440195.1 CDS ESA_04178 NC_009778.1 4134069 4134818 R COG: NOG13334 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4134069..4134818) Cronobacter sakazakii ATCC BAA-894 5550648 YP_001440196.1 CDS ESA_04179 NC_009778.1 4134931 4135950 R KEGG: efa:EF1922 0.0018 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4134931..4135950) Cronobacter sakazakii ATCC BAA-894 5550621 YP_001440197.1 CDS ESA_04180 NC_009778.1 4136152 4136790 D COG: COG3443 Predicted periplasmic or secreted protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4136152..4136790 Cronobacter sakazakii ATCC BAA-894 5550598 YP_001440198.1 CDS ESA_04181 NC_009778.1 4136837 4137499 R KEGG: bxe:Bxe_A4171 4.6e-05 putative cytochrome c oxidase K00403; COG: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Psort location: extracellular, including cell wall, score: 9; putative outer membrane lipoprotein complement(4136837..4137499) Cronobacter sakazakii ATCC BAA-894 5550610 YP_001440199.1 CDS ESA_04182 NC_009778.1 4137732 4140011 D KEGG: sfx:S4184 0. bisC; biotin sulfoxide reductase K08351; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: cytoplasmic, score: 23; hypothetical protein 4137732..4140011 Cronobacter sakazakii ATCC BAA-894 5550588 YP_001440200.1 CDS ESA_04183 NC_009778.1 4139980 4140420 R KEGG: sec:SC3575 7.6e-47 yiaC; putative acetyltransferase K03826; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4139980..4140420) Cronobacter sakazakii ATCC BAA-894 5550589 YP_001440201.1 CDS ESA_04184 NC_009778.1 4140417 4140980 R KEGG: ecc:c4367 5.1e-73 tag; DNA-3-methyladenine glycosylase I K01246; COG: COG2818 3-methyladenine DNA glycosylase; Psort location: cytoskeletal, score: 9; hypothetical protein complement(4140417..4140980) Cronobacter sakazakii ATCC BAA-894 5550586 YP_001440202.1 CDS ESA_04185 NC_009778.1 4141137 4141766 D COG: COG5571 Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion; Psort location: cytoplasmic, score: 23; hypothetical protein 4141137..4141766 Cronobacter sakazakii ATCC BAA-894 5550575 YP_001440203.1 CDS ESA_04186 NC_009778.1 4141923 4143125 D COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4141923..4143125 Cronobacter sakazakii ATCC BAA-894 5550562 YP_001440204.1 CDS ESA_04187 NC_009778.1 4143217 4143675 D KEGG: reh:H16_A1791 6.2e-29 predicted redox protein, regulator of disulfide bond formation K01768; COG: COG1764 Predicted redox protein, regulator of disulfide bond formation; Psort location: cytoplasmic, score: 23; hypothetical protein 4143217..4143675 Cronobacter sakazakii ATCC BAA-894 5550559 YP_001440205.1 CDS ESA_04188 NC_009778.1 4143889 4145568 D catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4143889..4145568 Cronobacter sakazakii ATCC BAA-894 5550563 YP_001440207.1 CDS ESA_04191 NC_009778.1 4145793 4146251 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4145793..4146251) Cronobacter sakazakii ATCC BAA-894 5550549 YP_001440208.1 CDS ESA_04192 NC_009778.1 4146241 4146699 R COG: NOG35673 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4146241..4146699) Cronobacter sakazakii ATCC BAA-894 5550511 YP_001440209.1 CDS ESA_04193 NC_009778.1 4147928 4149535 D KEGG: shn:Shewana3_2650 1.2e-121 acetate kinase K00925; COG: COG0747 ABC-type dipeptide transport system, periplasmic component; Psort location: cytoplasmic, score: 23; hypothetical protein 4147928..4149535 Cronobacter sakazakii ATCC BAA-894 5550513 YP_001440210.1 CDS ESA_04194 NC_009778.1 4149731 4150750 D transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4149731..4150750 Cronobacter sakazakii ATCC BAA-894 5550429 YP_001440211.1 CDS ESA_04195 NC_009778.1 4150760 4151662 D KEGG: bpm:BURPS1710b_A0449 1.9e-05 glycine betaine/L-proline ABC transporter, permease protein K02001; COG: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: endoplasmic reticulum, score: 9; dipeptide transporter 4150760..4151662 Cronobacter sakazakii ATCC BAA-894 5550480 YP_001440212.1 CDS dppD NC_009778.1 4151674 4152669 D DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 4151674..4152669 Cronobacter sakazakii ATCC BAA-894 5550450 YP_001440213.1 CDS dppF NC_009778.1 4152656 4153669 D Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 4152656..4153669 Cronobacter sakazakii ATCC BAA-894 5550462 YP_001440214.1 CDS ESA_04198 NC_009778.1 4153641 4153814 D Psort location: mitochondrial, score: 23; hypothetical protein 4153641..4153814 Cronobacter sakazakii ATCC BAA-894 5550464 YP_001440215.1 CDS ESA_04199 NC_009778.1 4153975 4155660 R COG: NOG05994 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4153975..4155660) Cronobacter sakazakii ATCC BAA-894 5550446 YP_001440216.1 CDS ESA_04200 NC_009778.1 4155653 4155850 R COG: NOG15366 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4155653..4155850) Cronobacter sakazakii ATCC BAA-894 5550444 YP_001440217.1 CDS ESA_04201 NC_009778.1 4155847 4157421 R KEGG: vfi:VFA0886 1.5e-23 zinc metalloprotease; COG: NOG14695 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4155847..4157421) Cronobacter sakazakii ATCC BAA-894 5550428 YP_001440218.1 CDS ESA_04202 NC_009778.1 4157594 4157797 D COG: NOG13865 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 4157594..4157797 Cronobacter sakazakii ATCC BAA-894 5550412 YP_001440219.1 CDS ESA_04203 NC_009778.1 4157794 4158522 D KEGG: ava:Ava_4268 0.00020 anion-transporting ATPase K01551; COG: COG1192 ATPases involved in chromosome partitioning; Psort location: cytoplasmic, score: 23; hypothetical protein 4157794..4158522 Cronobacter sakazakii ATCC BAA-894 5550395 YP_001440220.1 CDS bcsA NC_009778.1 4158519 4161137 D polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 4158519..4161137 Cronobacter sakazakii ATCC BAA-894 5550385 YP_001440221.1 CDS ESA_04205 NC_009778.1 4161148 4163580 D binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 4161148..4163580 Cronobacter sakazakii ATCC BAA-894 5550224 YP_001440222.1 CDS ESA_04206 NC_009778.1 4163587 4164702 D catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 4163587..4164702 Cronobacter sakazakii ATCC BAA-894 5550403 YP_001440223.1 CDS ESA_04207 NC_009778.1 4164684 4168187 D cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 4164684..4168187 Cronobacter sakazakii ATCC BAA-894 5550384 YP_001440224.1 CDS ESA_04208 NC_009778.1 4168344 4170269 D HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase 4168344..4170269 Cronobacter sakazakii ATCC BAA-894 5550379 YP_001440225.1 CDS ESA_04209 NC_009778.1 4170423 4171736 D involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4170423..4171736 Cronobacter sakazakii ATCC BAA-894 5550380 YP_001440226.1 CDS ESA_04210 NC_009778.1 4171936 4173426 D KEGG: eci:UTI89_C4059 1.5e-206 yhjJ; protein YhjJ precursor K01412; COG: COG0612 Predicted Zn-dependent peptidases; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4171936..4173426 Cronobacter sakazakii ATCC BAA-894 5550359 YP_001440227.1 CDS ESA_04211 NC_009778.1 4173513 4174445 R KEGG: ecs:ECs4406 3.9e-137 ketodeoxygluconokinase K00874; COG: COG0524 Sugar kinases, ribokinase family; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4173513..4174445) Cronobacter sakazakii ATCC BAA-894 5550301 YP_001440228.1 CDS ESA_04212 NC_009778.1 4174678 4175451 D in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 4174678..4175451 Cronobacter sakazakii ATCC BAA-894 5550348 YP_001440229.1 CDS ESA_04213 NC_009778.1 4175516 4177573 D COG: COG2982 Uncharacterized protein involved in outer membrane biogenesis; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4175516..4177573 Cronobacter sakazakii ATCC BAA-894 5550300 YP_001440230.1 CDS ESA_04214 NC_009778.1 4177864 4179192 R KEGG: cal:orf19.2425 5.8e-05 highly conserved hypothetical protein K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(4177864..4179192) Cronobacter sakazakii ATCC BAA-894 5550357 YP_001440231.1 CDS ESA_04215 NC_009778.1 4179467 4180501 R KEGG: eci:UTI89_C4054 6.6e-135 yhjD; hypothetical protein; COG: COG1295 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(4179467..4180501) Cronobacter sakazakii ATCC BAA-894 5549943 YP_001440232.1 CDS ESA_04216 NC_009778.1 4180554 4181453 R KEGG: shn:Shewana3_3435 1.1e-10 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4180554..4181453) Cronobacter sakazakii ATCC BAA-894 5550353 YP_001440233.1 CDS ESA_04217 NC_009778.1 4181572 4182330 D KEGG: pen:PSEEN1303 5.4e-85 oxidoreductase, short-chain alcohol dehydrogenase/reductase family; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein 4181572..4182330 Cronobacter sakazakii ATCC BAA-894 5550089 YP_001440234.1 CDS ESA_04218 NC_009778.1 4182375 4182773 R COG: COG3111 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4182375..4182773) Cronobacter sakazakii ATCC BAA-894 5550337 YP_001440235.1 CDS ESA_04219 NC_009778.1 4183088 4183654 R KEGG: eca:ECA3191 1.5e-18 putative acetyltransferase K00676; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4183088..4183654) Cronobacter sakazakii ATCC BAA-894 5550349 YP_001440236.1 CDS ESA_04220 NC_009778.1 4183685 4183867 D Psort location: cytoplasmic, score: 23; hypothetical protein 4183685..4183867 Cronobacter sakazakii ATCC BAA-894 5550424 YP_001440237.1 CDS ESA_04221 NC_009778.1 4183925 4185526 D COG: NOG26124 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 4183925..4185526 Cronobacter sakazakii ATCC BAA-894 5550401 YP_001440238.1 CDS ESA_04222 NC_009778.1 4185604 4186956 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(4185604..4186956) Cronobacter sakazakii ATCC BAA-894 5550049 YP_001440239.1 CDS ESA_04223 NC_009778.1 4187031 4187873 R COG: COG2961 Protein involved in catabolism of external DNA; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4187031..4187873) Cronobacter sakazakii ATCC BAA-894 5550375 YP_001440240.1 CDS ESA_04224 NC_009778.1 4188021 4190108 D KEGG: eci:UTI89_C4017 0. prlC, opdA; oligopeptidase A K01414; COG: COG0339 Zn-dependent oligopeptidases; Psort location: cytoplasmic, score: 23; oligopeptidase A 4188021..4190108 Cronobacter sakazakii ATCC BAA-894 5550124 YP_001440241.1 CDS ESA_04225 NC_009778.1 4190117 4190869 D predicted SAM-dependent methyltransferase; putative methyltransferase 4190117..4190869 Cronobacter sakazakii ATCC BAA-894 5550453 YP_001440242.1 CDS ESA_04226 NC_009778.1 4190969 4191406 R COG: COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4190969..4191406) Cronobacter sakazakii ATCC BAA-894 5550378 YP_001440243.1 CDS ESA_04227 NC_009778.1 4191801 4192136 D ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 4191801..4192136 Cronobacter sakazakii ATCC BAA-894 5550407 YP_001440244.1 CDS ESA_04228 NC_009778.1 4192187 4193689 R COG: COG0306 Phosphate/sulphate permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(4192187..4193689) Cronobacter sakazakii ATCC BAA-894 5550460 YP_001440245.1 CDS ESA_04229 NC_009778.1 4193919 4195121 D KEGG: ape:APE_2421 0.00031 electoron transfer flavoprotein-quinone oxidoreductase K00313; COG: COG2081 Predicted flavoproteins; Psort location: cytoplasmic, score: 23; hypothetical protein 4193919..4195121 Cronobacter sakazakii ATCC BAA-894 5550509 YP_001440246.1 CDS ESA_04230 NC_009778.1 4194006 4195133 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4194006..4195133) Cronobacter sakazakii ATCC BAA-894 5550516 YP_001440247.1 CDS ESA_04231 NC_009778.1 4195312 4195554 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4195312..4195554) Cronobacter sakazakii ATCC BAA-894 5550512 YP_001440248.1 CDS ESA_04232 NC_009778.1 4195618 4196106 D Psort location: cytoplasmic, score: 23; hypothetical protein 4195618..4196106 Cronobacter sakazakii ATCC BAA-894 5550458 YP_001440249.1 CDS ESA_04233 NC_009778.1 4197236 4198216 D COG: COG2801 Transposase and inactivated derivatives; Psort location: cytoplasmic, score: 23; hypothetical protein 4197236..4198216 Cronobacter sakazakii ATCC BAA-894 5550483 YP_001440250.1 CDS ESA_04234 NC_009778.1 4198305 4199876 D COG: NOG19979 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 4198305..4199876 Cronobacter sakazakii ATCC BAA-894 5550602 YP_001440251.1 CDS ESA_04235 NC_009778.1 4200045 4200323 R COG: COG3544 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(4200045..4200323) Cronobacter sakazakii ATCC BAA-894 5550557 YP_001440252.1 CDS ESA_04236 NC_009778.1 4200543 4201037 R COG: NOG30724 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(4200543..4201037) Cronobacter sakazakii ATCC BAA-894 5550600 YP_001440253.1 CDS ESA_04237 NC_009778.1 4201219 4202700 R KEGG: ecs:ECs0608 2.7e-138 putative 2-component sensor protein K07644; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 23; sensor kinase CusS complement(4201219..4202700) Cronobacter sakazakii ATCC BAA-894 5550663 YP_001440254.1 CDS ESA_04238 NC_009778.1 4202693 4203373 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(4202693..4203373) Cronobacter sakazakii ATCC BAA-894 5550689 YP_001440255.1 CDS ESA_04239 NC_009778.1 4203563 4204948 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 4203563..4204948 Cronobacter sakazakii ATCC BAA-894 5550684 YP_001440256.1 CDS ESA_04240 NC_009778.1 4204976 4205329 D COG: COG5569 Uncharacterized conserved protein; Psort location: extracellular, including cell wall, score: 9; periplasmic copper-binding protein 4204976..4205329 Cronobacter sakazakii ATCC BAA-894 5550569 YP_001440257.1 CDS ESA_04241 NC_009778.1 4205443 4206735 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 4205443..4206735 Cronobacter sakazakii ATCC BAA-894 5550731 YP_001440258.1 CDS ESA_04242 NC_009778.1 4206746 4209892 D KEGG: eci:UTI89_C2351 6.7e-58 yegO; hypothetical protein YegO K07789; COG: COG3696 Putative silver efflux pump; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4206746..4209892 Cronobacter sakazakii ATCC BAA-894 5550662 YP_001440259.1 CDS ESA_04243 NC_009778.1 4209979 4210419 D COG: COG3019 Predicted metal-binding protein; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4209979..4210419 Cronobacter sakazakii ATCC BAA-894 5550680 YP_001440260.1 CDS ESA_04244 NC_009778.1 4210600 4210851 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4210600..4210851) Cronobacter sakazakii ATCC BAA-894 5550698 YP_001440261.1 CDS ESA_04245 NC_009778.1 4210945 4212993 D KEGG: sme:SMa1087 9.4e-239 putative cation transport P-type ATPase; COG: COG2217 Cation transport ATPase; Psort location: plasma membrane, score: 23; hypothetical protein 4210945..4212993 Cronobacter sakazakii ATCC BAA-894 5550708 YP_001440262.1 CDS ESA_04246 NC_009778.1 4213034 4213231 D COG: NOG16192 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 4213034..4213231 Cronobacter sakazakii ATCC BAA-894 5550498 YP_001440263.1 CDS ESA_04247 NC_009778.1 4213265 4213615 R KEGG: ece:Z2908 1.1e-18 yebA; hypothetical protein; COG: COG0739 Membrane proteins related to metalloendopeptidases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4213265..4213615) Cronobacter sakazakii ATCC BAA-894 5550734 YP_001440264.1 CDS ESA_04248 NC_009778.1 4214291 4214548 R COG: NOG30724 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(4214291..4214548) Cronobacter sakazakii ATCC BAA-894 5550718 YP_001440265.1 CDS ESA_04249 NC_009778.1 4214969 4216792 D KEGG: gbe:GbCGDNIH1_2030 6.8e-149 multicopper oxidase PcoA; COG: COG2132 Putative multicopper oxidases; Psort location: mitochondrial, score: 23; hypothetical protein 4214969..4216792 Cronobacter sakazakii ATCC BAA-894 5550779 YP_001440266.1 CDS ESA_04250 NC_009778.1 4216789 4217688 D COG: COG3667 Uncharacterized protein involved in copper resistance; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4216789..4217688 Cronobacter sakazakii ATCC BAA-894 5550676 YP_001440267.1 CDS ESA_04251 NC_009778.1 4217728 4218108 D COG: COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4217728..4218108 Cronobacter sakazakii ATCC BAA-894 5550743 YP_001440268.1 CDS ESA_04252 NC_009778.1 4218113 4219042 D COG: COG1276 Putative copper export protein; Psort location: plasma membrane, score: 23; hypothetical protein 4218113..4219042 Cronobacter sakazakii ATCC BAA-894 5550771 YP_001440269.1 CDS ESA_04253 NC_009778.1 4219097 4219777 D KEGG: rha:RHA1_ro05622 1.9e-41 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: cytoplasmic, score: 23; hypothetical protein 4219097..4219777 Cronobacter sakazakii ATCC BAA-894 5550742 YP_001440270.1 CDS ESA_04254 NC_009778.1 4219774 4221174 D KEGG: dar:Daro_2258 5.6e-83 heavy metal sensor kinase K07644; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4219774..4221174 Cronobacter sakazakii ATCC BAA-894 5550526 YP_001440271.1 CDS ESA_04255 NC_009778.1 4221392 4221826 D COG: NOG30724 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 4221392..4221826 Cronobacter sakazakii ATCC BAA-894 5549009 YP_001440272.1 CDS ESA_04256 NC_009778.1 4222296 4223711 R KEGG: ece:Z2491 3.7e-93 putative glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4222296..4223711) Cronobacter sakazakii ATCC BAA-894 5550492 YP_001440273.1 CDS ESA_04257 NC_009778.1 4224006 4224518 D KEGG: eci:UTI89_C1901 1.7e-24 nlpC; probable lipoprotein NlpC precursor; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4224006..4224518 Cronobacter sakazakii ATCC BAA-894 5550587 YP_001440274.1 CDS ESA_04258 NC_009778.1 4224523 4225536 R KEGG: tbd:Tbd_2668 1.0e-11 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4224523..4225536) Cronobacter sakazakii ATCC BAA-894 5550699 YP_001440275.1 CDS ESA_04259 NC_009778.1 4225735 4226925 D KEGG: sgl:SG1589 1.0e-05 NADH dehydrogenase I subunit N K00343; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 4225735..4226925 Cronobacter sakazakii ATCC BAA-894 5550331 YP_001440276.1 CDS ESA_04260 NC_009778.1 4226964 4227521 R COG: NOG07879 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(4226964..4227521) Cronobacter sakazakii ATCC BAA-894 5550336 YP_001440277.1 CDS ESA_04262 NC_009778.1 4227595 4228260 R COG: COG1738 Uncharacterized conserved protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4227595..4228260) Cronobacter sakazakii ATCC BAA-894 5550335 YP_001440278.1 CDS ESA_04261 NC_009778.1 4227613 4228314 D Psort location: nuclear, score: 23; hypothetical protein 4227613..4228314 Cronobacter sakazakii ATCC BAA-894 5550327 YP_001440279.1 CDS ESA_04263 NC_009778.1 4228466 4228711 D TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 4228466..4228711 Cronobacter sakazakii ATCC BAA-894 5550345 YP_001440280.1 CDS ESA_04264 NC_009778.1 4228899 4229882 D COG: COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4228899..4229882 Cronobacter sakazakii ATCC BAA-894 5550328 YP_001440281.1 CDS ESA_04265 NC_009778.1 4229931 4230440 D COG: COG3090 TRAP-type C4-dicarboxylate transport system, small permease component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4229931..4230440 Cronobacter sakazakii ATCC BAA-894 5548524 YP_001440282.1 CDS ESA_04266 NC_009778.1 4230452 4231738 D COG: COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; Psort location: plasma membrane, score: 23; hypothetical protein 4230452..4231738 Cronobacter sakazakii ATCC BAA-894 5549997 YP_001440283.1 CDS zntA NC_009778.1 4232005 4234251 R P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase complement(4232005..4234251) Cronobacter sakazakii ATCC BAA-894 5550315 YP_001440284.1 CDS ESA_04267 NC_009778.1 4234236 4234844 D KEGG: bpm:BURPS1710b_A0954 0.00041 DJ-1/PfpI family protein; Psort location: nuclear, score: 23; hypothetical protein 4234236..4234844 Cronobacter sakazakii ATCC BAA-894 5550314 YP_001440285.1 CDS ESA_04269 NC_009778.1 4234329 4234955 R COG: COG3714 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4234329..4234955) Cronobacter sakazakii ATCC BAA-894 5550207 YP_001440286.1 CDS ESA_04270 NC_009778.1 4235096 4235461 D COG: NOG09778 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4235096..4235461 Cronobacter sakazakii ATCC BAA-894 5548516 YP_001440287.1 CDS ESA_04271 NC_009778.1 4235761 4236030 R COG: COG3776 Predicted membrane protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4235761..4236030) Cronobacter sakazakii ATCC BAA-894 5550225 YP_001440288.1 CDS rsmD NC_009778.1 4236020 4236616 R catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase complement(4236020..4236616) Cronobacter sakazakii ATCC BAA-894 5550307 YP_001440289.1 CDS ESA_04273 NC_009778.1 4236806 4238359 D signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 4236806..4238359 Cronobacter sakazakii ATCC BAA-894 5549996 YP_001440290.1 CDS ESA_04274 NC_009778.1 4238362 4239030 D putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 4238362..4239030 Cronobacter sakazakii ATCC BAA-894 5550232 YP_001440291.1 CDS ftsX NC_009778.1 4239008 4240078 D putative ABC transporter, membrane protein; cell division protein FtsX 4239008..4240078 Cronobacter sakazakii ATCC BAA-894 5550055 YP_001440292.1 CDS ESA_04276 NC_009778.1 4240340 4241197 D binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 4240340..4241197 Cronobacter sakazakii ATCC BAA-894 5552386 YP_001440293.1 CDS ESA_04277 NC_009778.1 4241246 4242727 R KEGG: reh:H16_B0980 1.2e-151 transcriptional regulator, MocR family; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4241246..4242727) Cronobacter sakazakii ATCC BAA-894 5552374 YP_001440294.1 CDS ESA_04278 NC_009778.1 4242918 4244123 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 4242918..4244123 Cronobacter sakazakii ATCC BAA-894 5552383 YP_001440295.1 CDS ESA_04279 NC_009778.1 4243245 4244513 R COG: COG1226 Kef-type K+ transport systems, predicted NAD-binding component; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4243245..4244513) Cronobacter sakazakii ATCC BAA-894 5552368 YP_001440296.1 CDS ESA_04280 NC_009778.1 4244557 4245798 D KEGG: tde:TDE2249 0.00048 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000; COG: COG0814 Amino acid permeases; Psort location: plasma membrane, score: 23; hypothetical protein 4244557..4245798 Cronobacter sakazakii ATCC BAA-894 5552370 YP_001440297.1 CDS ESA_04281 NC_009778.1 4245902 4247152 D KEGG: ava:Ava_2791 0.0016 serine/threonine protein kinase K00903; COG: COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4245902..4247152 Cronobacter sakazakii ATCC BAA-894 5552302 YP_001440298.1 CDS ESA_04282 NC_009778.1 4247432 4247824 R COG: NOG09777 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4247432..4247824) Cronobacter sakazakii ATCC BAA-894 5552109 YP_001440299.1 CDS ESA_04283 NC_009778.1 4248247 4248516 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4248247..4248516 Cronobacter sakazakii ATCC BAA-894 5552309 YP_001440300.1 CDS ESA_04284 NC_009778.1 4248584 4249510 D LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 4248584..4249510 Cronobacter sakazakii ATCC BAA-894 5552303 YP_001440301.1 CDS livM NC_009778.1 4249507 4250787 D Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 4249507..4250787 Cronobacter sakazakii ATCC BAA-894 5552305 YP_001440302.1 CDS livG NC_009778.1 4250784 4251551 D Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4250784..4251551 Cronobacter sakazakii ATCC BAA-894 5552300 YP_001440303.1 CDS livF NC_009778.1 4251553 4252266 D with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4251553..4252266 Cronobacter sakazakii ATCC BAA-894 5552270 YP_001440304.1 CDS ESA_04288 NC_009778.1 4252405 4252626 D COG: COG2161 Antitoxin of toxin-antitoxin stability system; Psort location: cytoplasmic, score: 23; hypothetical protein 4252405..4252626 Cronobacter sakazakii ATCC BAA-894 5552229 YP_001440305.1 CDS ESA_04289 NC_009778.1 4252626 4252994 D COG: COG3654 Prophage maintenance system killer protein; Psort location: cytoplasmic, score: 23; hypothetical protein 4252626..4252994 Cronobacter sakazakii ATCC BAA-894 5552231 YP_001440306.1 CDS ESA_04290 NC_009778.1 4253093 4254484 D with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 4253093..4254484 Cronobacter sakazakii ATCC BAA-894 5552234 YP_001440307.1 CDS ESA_04291 NC_009778.1 4254639 4255508 D with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 4254639..4255508 Cronobacter sakazakii ATCC BAA-894 5552147 YP_001440308.1 CDS ESA_04292 NC_009778.1 4255505 4256350 D with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 4255505..4256350 Cronobacter sakazakii ATCC BAA-894 5552103 YP_001440309.1 CDS ugpC NC_009778.1 4256352 4257425 D part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 4256352..4257425 Cronobacter sakazakii ATCC BAA-894 5552181 YP_001440310.1 CDS ugpQ NC_009778.1 4257422 4258162 D hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase 4257422..4258162 Cronobacter sakazakii ATCC BAA-894 5552137 YP_001440311.1 CDS ESA_04295 NC_009778.1 4258159 4258626 R KEGG: ddi:DDB0229429 4.4e-07 putative CMGC family protein kinase K08825; COG: NOG08680 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4258159..4258626) Cronobacter sakazakii ATCC BAA-894 5552142 YP_001440312.1 CDS ggt NC_009778.1 4258752 4260518 D periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 4258752..4260518 Cronobacter sakazakii ATCC BAA-894 5552221 YP_001440313.1 CDS ESA_04297 NC_009778.1 4260757 4261254 R KEGG: ecs:ECs4290 8.7e-62 putative acetyltransferase K03825; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4260757..4261254) Cronobacter sakazakii ATCC BAA-894 5552249 YP_001440314.1 CDS ESA_04299 NC_009778.1 4261564 4262604 D KEGG: ecp:ECP_3535 1.9e-160 putative oxidoreductase YhhX; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: mitochondrial, score: 23; putative dehydrogenase 4261564..4262604 Cronobacter sakazakii ATCC BAA-894 5552317 YP_001440315.1 CDS ESA_04300 NC_009778.1 4262726 4263421 D KEGG: shn:Shewana3_3385 3.8e-14 hypoxanTHIne phosphoribosyltransferase K00760; COG: COG1741 Pirin-related protein; Psort location: cytoplasmic, score: 23; hypothetical protein 4262726..4263421 Cronobacter sakazakii ATCC BAA-894 5549921 YP_001440316.1 CDS ESA_04301 NC_009778.1 4263526 4264521 D KEGG: efa:EF1922 1.1e-06 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 4263526..4264521 Cronobacter sakazakii ATCC BAA-894 5550139 YP_001440317.1 CDS ESA_04303 NC_009778.1 4264552 4265058 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4264552..4265058) Cronobacter sakazakii ATCC BAA-894 5548308 YP_001440318.1 CDS gntK NC_009778.1 4264663 4265190 D thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 4264663..4265190 Cronobacter sakazakii ATCC BAA-894 5548390 YP_001440319.1 CDS ESA_04304 NC_009778.1 4265236 4266534 D KEGG: eci:UTI89_C3106 1.7e-65 ygbN; hypothetical permease YgbN K03299; COG: COG2610 H+/gluconate symporter and related permeases; Psort location: plasma membrane, score: 23; low affinity gluconate transporter 4265236..4266534 Cronobacter sakazakii ATCC BAA-894 5548338 YP_001440320.1 CDS ESA_04305 NC_009778.1 4266573 4267322 R COG: COG2184 Protein involved in cell division; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4266573..4267322) Cronobacter sakazakii ATCC BAA-894 5548249 YP_001440321.1 CDS ESA_04306 NC_009778.1 4267319 4267489 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4267319..4267489) Cronobacter sakazakii ATCC BAA-894 5548385 YP_001440322.1 CDS ESA_04307 NC_009778.1 4267634 4268227 R YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase complement(4267634..4268227) Cronobacter sakazakii ATCC BAA-894 5548421 YP_001440323.1 CDS ESA_04308 NC_009778.1 4268396 4269502 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4268396..4269502 Cronobacter sakazakii ATCC BAA-894 5549974 YP_001440324.1 CDS ESA_04309 NC_009778.1 4269737 4271965 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 4269737..4271965 Cronobacter sakazakii ATCC BAA-894 5548405 YP_001440325.1 CDS ESA_04310 NC_009778.1 4271952 4273934 D catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme 4271952..4273934 Cronobacter sakazakii ATCC BAA-894 5548151 YP_001440326.1 CDS glgC NC_009778.1 4273948 4275231 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 4273948..4275231 Cronobacter sakazakii ATCC BAA-894 5548357 YP_001440327.1 CDS glgA NC_009778.1 4275330 4276763 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 4275330..4276763 Cronobacter sakazakii ATCC BAA-894 5551973 YP_001440328.1 CDS ESA_04313 NC_009778.1 4276776 4279223 D KEGG: spt:SPA3385 0. glgP; glycogen phosphorylase K00688; COG: COG0058 Glucan phosphorylase; Psort location: cytoplasmic, score: 23; hypothetical protein 4276776..4279223 Cronobacter sakazakii ATCC BAA-894 5552188 YP_001440329.1 CDS ESA_04314 NC_009778.1 4279292 4279753 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 4279292..4279753 Cronobacter sakazakii ATCC BAA-894 5548190 YP_001440330.1 CDS ESA_04315 NC_009778.1 4279744 4281267 R KEGG: ava:Ava_3170 5.0e-34 putative diguanylate cyclase (GGDEF domain) K02488; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4279744..4281267) Cronobacter sakazakii ATCC BAA-894 5548221 YP_001440331.1 CDS glpD NC_009778.1 4281451 4282968 R in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase complement(4281451..4282968) Cronobacter sakazakii ATCC BAA-894 5552470 YP_001440332.1 CDS glpE NC_009778.1 4283175 4283519 D belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 4283175..4283519 Cronobacter sakazakii ATCC BAA-894 5551656 YP_001440333.1 CDS ESA_04318 NC_009778.1 4283595 4284425 D protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 4283595..4284425 Cronobacter sakazakii ATCC BAA-894 5552019 YP_001440334.1 CDS ESA_04319 NC_009778.1 4284406 4285209 D represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 4284406..4285209 Cronobacter sakazakii ATCC BAA-894 5548314 YP_001440335.1 CDS ESA_04320 NC_009778.1 4285414 4288119 R Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT complement(4285414..4288119) Cronobacter sakazakii ATCC BAA-894 5552379 YP_001440336.1 CDS ESA_04321 NC_009778.1 4288718 4291120 D KEGG: sec:SC3446 0. malP; maltodextrin phosphorylase K00688; COG: COG0058 Glucan phosphorylase; Psort location: cytoplasmic, score: 23; hypothetical protein 4288718..4291120 Cronobacter sakazakii ATCC BAA-894 5552186 YP_001440337.1 CDS malQ NC_009778.1 4291132 4293240 D amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 4291132..4293240 Cronobacter sakazakii ATCC BAA-894 5548369 YP_001440338.1 CDS ESA_04323 NC_009778.1 4293510 4293722 D COG: COG1278 Cold shock proteins; Psort location: cytoplasmic, score: 23; major cold shock protein 4293510..4293722 Cronobacter sakazakii ATCC BAA-894 5548469 YP_001440339.1 CDS ESA_04324 NC_009778.1 4293881 4294456 R cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein complement(4293881..4294456) Cronobacter sakazakii ATCC BAA-894 5548204 YP_001440340.1 CDS ESA_04325 NC_009778.1 4294515 4295075 R KEGG: reh:H16_A0339 2.9e-22 predicted amidophosphoribosyltransferase; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4294515..4295075) Cronobacter sakazakii ATCC BAA-894 5548365 YP_001440341.1 CDS ESA_04326 NC_009778.1 4295232 4296011 D KEGG: eci:UTI89_C3913 1.6e-99 bioH; carboxylesterase involved in biosynthesis of pimeloyl-CoA/carboxylesterase K02170; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein 4295232..4296011 Cronobacter sakazakii ATCC BAA-894 5548192 YP_001440342.1 CDS ESA_04327 NC_009778.1 4296093 4296362 D COG: NOG30300 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 4296093..4296362 Cronobacter sakazakii ATCC BAA-894 5548233 YP_001440343.1 CDS ESA_04328 NC_009778.1 4296408 4296644 R COG: NOG13904 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(4296408..4296644) Cronobacter sakazakii ATCC BAA-894 5548295 YP_001440344.1 CDS feoB NC_009778.1 4296644 4298959 R cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B complement(4296644..4298959) Cronobacter sakazakii ATCC BAA-894 5548257 YP_001440345.1 CDS feoA NC_009778.1 4298986 4299210 R COG: COG1918 Fe2+ transport system protein A; Psort location: cytoplasmic, score: 23; ferrous iron transport protein A complement(4298986..4299210) Cronobacter sakazakii ATCC BAA-894 5548205 YP_001440346.1 CDS ESA_04331 NC_009778.1 4299299 4299430 R Psort location: mitochondrial, score: 23; hypothetical protein complement(4299299..4299430) Cronobacter sakazakii ATCC BAA-894 5548248 YP_001440347.1 CDS ESA_04332 NC_009778.1 4299880 4302207 R KEGG: bur:Bcep18194_A5099 1.1e-246 RNA binding S1; COG: COG2183 Transcriptional accessory protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4299880..4302207) Cronobacter sakazakii ATCC BAA-894 5548170 YP_001440348.1 CDS greB NC_009778.1 4302321 4302794 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB complement(4302321..4302794) Cronobacter sakazakii ATCC BAA-894 5548164 YP_001440349.1 CDS ompR NC_009778.1 4303097 4303855 D part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 4303097..4303855 Cronobacter sakazakii ATCC BAA-894 5548103 YP_001440350.1 CDS envZ NC_009778.1 4303852 4305198 D membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 4303852..4305198 Cronobacter sakazakii ATCC BAA-894 5548235 YP_001440351.1 CDS ESA_04336 NC_009778.1 4305259 4306878 R PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(4305259..4306878) Cronobacter sakazakii ATCC BAA-894 5548275 YP_001440352.1 CDS ESA_04337 NC_009778.1 4307064 4307282 D Psort location: mitochondrial, score: 23; hypothetical protein 4307064..4307282 Cronobacter sakazakii ATCC BAA-894 5548200 YP_001440353.1 CDS ESA_04338 NC_009778.1 4307094 4307240 R Psort location: nuclear, score: 23; hypothetical protein complement(4307094..4307240) Cronobacter sakazakii ATCC BAA-894 5548215 YP_001440354.1 CDS ESA_04339 NC_009778.1 4307301 4308995 D COG: NOG06297 non supervised orthologous group; Psort location: plasma membrane, score: 23; hypothetical protein 4307301..4308995 Cronobacter sakazakii ATCC BAA-894 5548270 YP_001440355.1 CDS hslO NC_009778.1 4309044 4309922 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin complement(4309044..4309922) Cronobacter sakazakii ATCC BAA-894 5548097 YP_001440356.1 CDS ESA_04341 NC_009778.1 4309946 4310347 R COG: COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); Psort location: nuclear, score: 23; ribosome-associated heat shock protein Hsp15 complement(4309946..4310347) Cronobacter sakazakii ATCC BAA-894 5548324 YP_001440357.1 CDS ESA_04342 NC_009778.1 4310347 4311027 R KEGG: bur:Bcep18194_A3622 0.00015 2-phosphoglycolate phosphatase K01091; COG: COG1011 Predicted hydrolase (HAD superfamily); Psort location: cytoplasmic, score: 23; hypothetical protein complement(4310347..4311027) Cronobacter sakazakii ATCC BAA-894 5548453 YP_001440358.1 CDS ESA_04343 NC_009778.1 4311090 4313228 R COG: NOG06324 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4311090..4313228) Cronobacter sakazakii ATCC BAA-894 5548149 YP_001440359.1 CDS nudE NC_009778.1 4313529 4314125 D ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 4313529..4314125 Cronobacter sakazakii ATCC BAA-894 5548328 YP_001440360.1 CDS mrcA NC_009778.1 4314213 4316765 R bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase complement(4314213..4316765) Cronobacter sakazakii ATCC BAA-894 5548316 YP_001440361.1 CDS ESA_04346 NC_009778.1 4316885 4317667 D COG: NOG05966 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 4316885..4317667 Cronobacter sakazakii ATCC BAA-894 5548184 YP_001440362.1 CDS ESA_04347 NC_009778.1 4317667 4318218 D COG: COG3166 Tfp pilus assembly protein PilN; Psort location: mitochondrial, score: 23; hypothetical protein 4317667..4318218 Cronobacter sakazakii ATCC BAA-894 5548466 YP_001440363.1 CDS ESA_04348 NC_009778.1 4318202 4318678 D COG: NOG13913 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 4318202..4318678 Cronobacter sakazakii ATCC BAA-894 5552425 YP_001440364.1 CDS ESA_04349 NC_009778.1 4318668 4319078 D COG: NOG12171 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4318668..4319078 Cronobacter sakazakii ATCC BAA-894 5551931 YP_001440365.1 CDS hofQ NC_009778.1 4319068 4320240 D outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 4319068..4320240 Cronobacter sakazakii ATCC BAA-894 5548150 YP_001440366.1 CDS aroK NC_009778.1 4320406 4321056 D type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 4320406..4321056 Cronobacter sakazakii ATCC BAA-894 5548182 YP_001440367.1 CDS aroB NC_009778.1 4321111 4322199 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 4321111..4322199 Cronobacter sakazakii ATCC BAA-894 5552203 YP_001440368.1 CDS ESA_04353 NC_009778.1 4322236 4322568 R Psort location: mitochondrial, score: 23; hypothetical protein complement(4322236..4322568) Cronobacter sakazakii ATCC BAA-894 5551400 YP_001440369.1 CDS ESA_04354 NC_009778.1 4322572 4323603 D KEGG: cal:orf19.575 1.3e-08 HYR5; similar to HYR1 K01186; COG: COG3266 Uncharacterized protein conserved in bacteria; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4322572..4323603 Cronobacter sakazakii ATCC BAA-894 5552185 YP_001440370.1 CDS ESA_04355 NC_009778.1 4323672 4324490 D KEGG: eco:b3387 2.0e-119 dam; DNA adenine methylase K06223; COG: COG0338 Site-specific DNA methylase; Psort location: cytoplasmic, score: 23; DNA adenine methylase 4323672..4324490 Cronobacter sakazakii ATCC BAA-894 5552222 YP_001440371.1 CDS ESA_04356 NC_009778.1 4324523 4325212 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 4324523..4325212 Cronobacter sakazakii ATCC BAA-894 5552360 YP_001440372.1 CDS ESA_04357 NC_009778.1 4325205 4325963 D catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 4325205..4325963 Cronobacter sakazakii ATCC BAA-894 5548478 YP_001440373.1 CDS ESA_04358 NC_009778.1 4325956 4326960 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 4325956..4326960 Cronobacter sakazakii ATCC BAA-894 5552151 YP_001440374.1 CDS ESA_04359 NC_009778.1 4326929 4327105 D Psort location: mitochondrial, score: 23; hypothetical protein 4326929..4327105 Cronobacter sakazakii ATCC BAA-894 5548161 YP_001440375.1 CDS ESA_04360 NC_009778.1 4327045 4327215 R COG: NOG13903 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(4327045..4327215) Cronobacter sakazakii ATCC BAA-894 5548315 YP_001440376.1 CDS ESA_04361 NC_009778.1 4327368 4328099 R may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR complement(4327368..4328099) Cronobacter sakazakii ATCC BAA-894 5549621 YP_001440377.1 CDS ESA_04362 NC_009778.1 4328201 4328986 R KEGG: eco:b3374 1.1e-102 frlD, yhfQ; fructoselysine 6-kinase K00924; COG: COG0524 Sugar kinases, ribokinase family; Psort location: cytoplasmic, score: 23; fructoselysine 6-kinase complement(4328201..4328986) Cronobacter sakazakii ATCC BAA-894 5552287 YP_001440378.1 CDS ESA_04363 NC_009778.1 4328983 4329813 R YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase complement(4328983..4329813) Cronobacter sakazakii ATCC BAA-894 5552488 YP_001440379.1 CDS frlB NC_009778.1 4329864 4330886 R catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase complement(4329864..4330886) Cronobacter sakazakii ATCC BAA-894 5552073 YP_001440380.1 CDS frlA NC_009778.1 4330908 4332248 R inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; putative fructoselysine transporter complement(4330908..4332248) Cronobacter sakazakii ATCC BAA-894 5552390 YP_001440381.1 CDS cysG NC_009778.1 4332533 4333906 R multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase complement(4332533..4333906) Cronobacter sakazakii ATCC BAA-894 5548171 YP_001440382.1 CDS nirD NC_009778.1 4334267 4334593 R involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit complement(4334267..4334593) Cronobacter sakazakii ATCC BAA-894 5548165 YP_001440383.1 CDS ESA_04368 NC_009778.1 4334590 4337136 R KEGG: stm:STM3474 0. nirB; nitrite reductase, large subunit K00362; COG: COG1251 NAD(P)H-nitrite reductase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4334590..4337136) Cronobacter sakazakii ATCC BAA-894 5548195 YP_001440384.1 CDS ESA_04369 NC_009778.1 4337451 4338638 R COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(4337451..4338638) Cronobacter sakazakii ATCC BAA-894 5548153 YP_001440385.1 CDS ESA_04370 NC_009778.1 4338914 4339486 D KEGG: stm:STM3472 2.8e-88 ppiA; peptidyl-prolyl cis-trans isomerase A (rotamase A) K03767; COG: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; Psort location: extracellular, including cell wall, score: 9; peptidyl-prolyl cis-trans isomerase A (rotamase A) 4338914..4339486 Cronobacter sakazakii ATCC BAA-894 5548193 YP_001440386.1 CDS ESA_04371 NC_009778.1 4339591 4339761 D COG: NOG18128 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 4339591..4339761 Cronobacter sakazakii ATCC BAA-894 5548396 YP_001440387.1 CDS ESA_04372 NC_009778.1 4339751 4340353 D COG: COG2184 Protein involved in cell division; Psort location: cytoplasmic, score: 23; cell filamentation protein Fic 4339751..4340353 Cronobacter sakazakii ATCC BAA-894 5548332 YP_001440388.1 CDS ESA_04373 NC_009778.1 4340384 4340947 D KEGG: ypa:YPA_3300 5.1e-73 para-aminobenzoate synthase glutamine amidotransferase component II K01664; COG: COG0512 Anthranilate/para-aminobenzoate synthases component II; Psort location: cytoplasmic, score: 23; hypothetical protein 4340384..4340947 Cronobacter sakazakii ATCC BAA-894 5548363 YP_001440389.1 CDS argD NC_009778.1 4341007 4342254 D DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 4341007..4342254 Cronobacter sakazakii ATCC BAA-894 5548417 YP_001440390.1 CDS ESA_04375 NC_009778.1 4342255 4344339 R KEGG: ssn:SSO_3489 1.1e-290 yhfK; hypothetical protein K01823; COG: COG1289 Predicted membrane protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(4342255..4344339) Cronobacter sakazakii ATCC BAA-894 5548474 YP_001440391.1 CDS ESA_04376 NC_009778.1 4344402 4345034 R complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein complement(4344402..4345034) Cronobacter sakazakii ATCC BAA-894 5548199 YP_001440392.1 CDS ESA_04377 NC_009778.1 4345345 4345752 D COG: COG1765 Predicted redox protein, regulator of disulfide bond formation; Psort location: cytoplasmic, score: 23; hypothetical protein 4345345..4345752 Cronobacter sakazakii ATCC BAA-894 5548251 YP_001440393.1 CDS ESA_04378 NC_009778.1 4345797 4346666 R KEGG: spt:SPA3330 2.0e-149 prkB; phosphoribulokinase K00855; COG: COG3954 Phosphoribulokinase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4345797..4346666) Cronobacter sakazakii ATCC BAA-894 5548178 YP_001440394.1 CDS ESA_04379 NC_009778.1 4346715 4346933 R COG: COG3089 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4346715..4346933) Cronobacter sakazakii ATCC BAA-894 5548140 YP_001440395.1 CDS ESA_04380 NC_009778.1 4346934 4347629 R COG: COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4346934..4347629) Cronobacter sakazakii ATCC BAA-894 5548243 YP_001440396.1 CDS ESA_04381 NC_009778.1 4347663 4347902 D Psort location: mitochondrial, score: 23; hypothetical protein 4347663..4347902 Cronobacter sakazakii ATCC BAA-894 5548271 YP_001440397.1 CDS ESA_04382 NC_009778.1 4348023 4348742 R KEGG: mth:MTH1315 6.7e-16 mutator MutT protein K01529; COG: COG1051 ADP-ribose pyrophosphatase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4348023..4348742) Cronobacter sakazakii ATCC BAA-894 5548197 YP_001440398.1 CDS ESA_04383 NC_009778.1 4348939 4349796 D KEGG: chu:CHU_2422 1.3e-35 prsA; phosphoribosylpyrophosphate synthetase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: cytoplasmic, score: 23; hypothetical protein 4348939..4349796 Cronobacter sakazakii ATCC BAA-894 5548208 YP_001440399.1 CDS ESA_04384 NC_009778.1 4349808 4351298 D KEGG: chu:CHU_2424 4.3e-124 nadV; nicotinamide phosphoribosyl transferase family protein K00763; COG: COG1488 Nicotinic acid phosphoribosyltransferase; Psort location: cytoplasmic, score: 23; putative nicotinate phosphoribosyltransferase 4349808..4351298 Cronobacter sakazakii ATCC BAA-894 5548394 YP_001440400.1 CDS ESA_04385 NC_009778.1 4351376 4352362 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4351376..4352362) Cronobacter sakazakii ATCC BAA-894 5548266 YP_001440401.1 CDS ESA_04386 NC_009778.1 4352405 4353526 R COG: COG3853 Uncharacterized protein involved in tellurite resistance; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4352405..4353526) Cronobacter sakazakii ATCC BAA-894 5548187 YP_001440402.1 CDS ESA_04387 NC_009778.1 4353882 4355792 R KEGG: bur:Bcep18194_A5345 6.6e-183 ABC transporter, fused ATPase subunits K06158; COG: COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Psort location: mitochondrial, score: 23; putative ABC transporter ATP-binding protein complement(4353882..4355792) Cronobacter sakazakii ATCC BAA-894 5548298 YP_001440403.1 CDS ESA_04388 NC_009778.1 4355916 4356470 D required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 4355916..4356470 Cronobacter sakazakii ATCC BAA-894 5548409 YP_001440404.1 CDS ESA_04389 NC_009778.1 4356470 4358275 D involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 4356470..4358275 Cronobacter sakazakii ATCC BAA-894 5548230 YP_001440405.1 CDS ESA_04390 NC_009778.1 4358287 4358487 D KEGG: syc:syc2139_c 0.0017 accD; acetyl-CoA carboxylase beta subunit K01963; COG: COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 4358287..4358487 Cronobacter sakazakii ATCC BAA-894 5548527 YP_001440406.1 CDS ESA_04392 NC_009778.1 4358570 4359124 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4358570..4359124) Cronobacter sakazakii ATCC BAA-894 5548674 YP_001440407.1 CDS ESA_04391 NC_009778.1 4358582 4359166 D rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 4358582..4359166 Cronobacter sakazakii ATCC BAA-894 5548793 YP_001440408.1 CDS ESA_04393 NC_009778.1 4359222 4359440 R COG: COG2900 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein complement(4359222..4359440) Cronobacter sakazakii ATCC BAA-894 5548791 YP_001440409.1 CDS ESA_04394 NC_009778.1 4359653 4360480 D rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 4359653..4360480 Cronobacter sakazakii ATCC BAA-894 5552398 YP_001440410.1 CDS ESA_04395 NC_009778.1 4360655 4361377 D COG: COG2964 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 4360655..4361377 Cronobacter sakazakii ATCC BAA-894 5548794 YP_001440411.1 CDS ESA_04396 NC_009778.1 4361377 4361763 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 4361377..4361763 Cronobacter sakazakii ATCC BAA-894 5548795 YP_001440412.1 CDS ESA_04397 NC_009778.1 4361763 4362122 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 4361763..4362122 Cronobacter sakazakii ATCC BAA-894 5548796 YP_001440413.1 CDS ESA_04398 NC_009778.1 4362131 4362418 D COG: COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur; Psort location: cytoplasmic, score: 23; hypothetical protein 4362131..4362418 Cronobacter sakazakii ATCC BAA-894 5548797 YP_004770511.1 CDS ESA_p2 NC_009778.1 4362545 4362919 D ribosomal protein L24 4362545..4362919 Cronobacter sakazakii ATCC BAA-894 11030700 YP_001440415.1 CDS ESA_04400 NC_009778.1 4363016 4363486 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 4363016..4363486 Cronobacter sakazakii ATCC BAA-894 5548798 YP_001440416.1 CDS ESA_04402 NC_009778.1 4363560 4365545 R COG: NOG09977 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(4363560..4365545) Cronobacter sakazakii ATCC BAA-894 5548378 YP_001440417.1 CDS ESA_04401 NC_009778.1 4363581 4365695 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 4363581..4365695 Cronobacter sakazakii ATCC BAA-894 5552403 YP_001440418.1 CDS ESA_04404 NC_009778.1 4365673 4366857 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(4365673..4366857) Cronobacter sakazakii ATCC BAA-894 5552354 YP_001440419.1 CDS ESA_04403 NC_009778.1 4365763 4366947 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4365763..4366947 Cronobacter sakazakii ATCC BAA-894 5548415 YP_001440420.1 CDS ESA_04405 NC_009778.1 4366944 4367351 R Psort location: mitochondrial, score: 23; hypothetical protein complement(4366944..4367351) Cronobacter sakazakii ATCC BAA-894 5552264 YP_001440421.1 CDS ESA_04406 NC_009778.1 4367387 4367863 D iron storage protein; bacterioferritin 4367387..4367863 Cronobacter sakazakii ATCC BAA-894 5552200 YP_001440422.1 CDS ESA_04407 NC_009778.1 4367867 4368334 R KEGG: csa:Csal_2176 4.1e-32 prepilin peptidase; COG: COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4367867..4368334) Cronobacter sakazakii ATCC BAA-894 5552490 YP_001440423.1 CDS ESA_pESA2p06554 NC_009779.1 406 702 D Psort location: mitochondrial, score: 23; ORF located using Blastx; hypothetical protein 406..702 Cronobacter sakazakii ATCC BAA-894 5552535 YP_001440424.1 CDS ESA_pESA2p06555 NC_009779.1 752 2488 D COG: NOG23110 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 752..2488 Cronobacter sakazakii ATCC BAA-894 5552506 YP_001440425.1 CDS ESA_pESA2p06556 NC_009779.1 2497 3246 D COG: NOG22282 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2497..3246 Cronobacter sakazakii ATCC BAA-894 5552511 YP_001440426.1 CDS ESA_pESA2p06557 NC_009779.1 3284 3757 D KEGG: noc:Noc_1464 3.5e-26 micrococcal nuclease (SNase-like) K01174; COG: COG1525 Micrococcal nuclease (thermonuclease) homologs; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 3284..3757 Cronobacter sakazakii ATCC BAA-894 5552512 YP_001440427.1 CDS ESA_pESA2p06558 NC_009779.1 3799 4158 D Psort location: endoplasmic reticulum, score: 9; hypothetical protein 3799..4158 Cronobacter sakazakii ATCC BAA-894 5552513 YP_001440428.1 CDS ESA_pESA2p06559 NC_009779.1 4197 4430 R Psort location: nuclear, score: 23; hypothetical protein complement(4197..4430) Cronobacter sakazakii ATCC BAA-894 5552514 YP_001440429.1 CDS ESA_pESA2p06560 NC_009779.1 4471 5118 R COG: NOG35487 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(4471..5118) Cronobacter sakazakii ATCC BAA-894 5552507 YP_001440430.1 CDS ESA_pESA2p06561 NC_009779.1 5552 6526 R COG: NOG19677 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(5552..6526) Cronobacter sakazakii ATCC BAA-894 5552508 YP_001440431.1 CDS ESA_pESA2p06562 NC_009779.1 6477 7724 R KEGG: sil:SPO1049 2.1e-83 DNA methylase, C-5 cytosine-specific family K00558; COG: COG0270 Site-specific DNA methylase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(6477..7724) Cronobacter sakazakii ATCC BAA-894 5552509 YP_001440432.1 CDS ESA_pESA2p06563 NC_009779.1 8539 9096 R COG: COG1961 Site-specific recombinases, DNA invertase Pin homologs; Psort location: cytoplasmic, score: 23; hypothetical protein complement(8539..9096) Cronobacter sakazakii ATCC BAA-894 5552510 YP_001440433.1 CDS ESA_pESA2p06564 NC_009779.1 9090 9461 R COG: NOG33302 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein complement(9090..9461) Cronobacter sakazakii ATCC BAA-894 5552502 YP_001440434.1 CDS ESA_pESA2p06565 NC_009779.1 9458 9958 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(9458..9958) Cronobacter sakazakii ATCC BAA-894 5552503 YP_001440435.1 CDS ESA_pESA2p06566 NC_009779.1 9955 10281 R Psort location: mitochondrial, score: 23; hypothetical protein complement(9955..10281) Cronobacter sakazakii ATCC BAA-894 5552504 YP_001440436.1 CDS ESA_pESA2p06567 NC_009779.1 10536 10892 R KEGG: aci:ACIAD0086 3.8e-06 epsM; bifunctional protein [includes: mannose-6-phosphate isomerase (phosphomannose isomerase) (PMI) (phosphohexomutase); mannose-1-phosphate guanylyl transferase (GDP) (GDP-mannose pyrophosphorylase) (GMP)] K00971:K01809; COG: COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; Psort location: cytoplasmic, score: 23; hypothetical protein complement(10536..10892) Cronobacter sakazakii ATCC BAA-894 5552505 YP_001440437.1 CDS ESA_pESA2p06568 NC_009779.1 10882 11283 R KEGG: mma:MM1164 1.1e-15 hypothetical nucleotidyltransferase; COG: COG2361 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(10882..11283) Cronobacter sakazakii ATCC BAA-894 5552498 YP_001440438.1 CDS ESA_pESA2p06569 NC_009779.1 11280 11576 R KEGG: tth:TTC1285 1.3e-12 nucleotidyltransferase; COG: COG1669 Predicted nucleotidyltransferases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(11280..11576) Cronobacter sakazakii ATCC BAA-894 5552499 YP_001440439.1 CDS ESA_pESA2p06570 NC_009779.1 11729 14695 D COG: COG4644 Transposase and inactivated derivatives, TnpA family; Psort location: cytoplasmic, score: 23; hypothetical protein 11729..14695 Cronobacter sakazakii ATCC BAA-894 5552500 YP_001440440.1 CDS ESA_pESA2p06571 NC_009779.1 14778 15182 D Psort location: nuclear, score: 23; hypothetical protein 14778..15182 Cronobacter sakazakii ATCC BAA-894 5552501 YP_001440441.1 CDS ESA_pESA2p06572 NC_009779.1 15496 16263 R Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(15496..16263) Cronobacter sakazakii ATCC BAA-894 5552527 YP_001440442.1 CDS ESA_pESA2p06573 NC_009779.1 17182 17781 R Psort location: mitochondrial, score: 23; hypothetical protein complement(17182..17781) Cronobacter sakazakii ATCC BAA-894 5552528 YP_001440443.1 CDS ESA_pESA2p06574 NC_009779.1 18344 18700 R COG: COG1396 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(18344..18700) Cronobacter sakazakii ATCC BAA-894 5552529 YP_001440444.1 CDS ESA_pESA2p06575 NC_009779.1 18948 19397 D COG: COG0250 Transcription antiterminator; Psort location: cytoplasmic, score: 23; ORF located using Blastx; hypothetical protein 18948..19397 Cronobacter sakazakii ATCC BAA-894 5552530 YP_001440445.1 CDS ESA_pESA2p06576 NC_009779.1 19472 19687 D Psort location: nuclear, score: 23; hypothetical protein 19472..19687 Cronobacter sakazakii ATCC BAA-894 5552515 YP_001440446.1 CDS ESA_pESA2p06577 NC_009779.1 19691 19912 D COG: NOG33328 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 19691..19912 Cronobacter sakazakii ATCC BAA-894 5552516 YP_001440447.1 CDS ESA_pESA2p06578 NC_009779.1 19928 20638 D COG: NOG17192 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 19928..20638 Cronobacter sakazakii ATCC BAA-894 5552517 YP_001440448.1 CDS ESA_pESA2p06579 NC_009779.1 20635 20913 D COG: NOG22876 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 20635..20913 Cronobacter sakazakii ATCC BAA-894 5552518 YP_001440449.1 CDS ESA_pESA2p06580 NC_009779.1 20926 23670 D COG: COG3451 Type IV secretory pathway, VirB4 components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 20926..23670 Cronobacter sakazakii ATCC BAA-894 5552531 YP_001440450.1 CDS ESA_pESA2p06581 NC_009779.1 23722 24390 D COG: NOG13363 non supervised orthologous group; Psort location: nuclear, score: 23; hypothetical protein 23722..24390 Cronobacter sakazakii ATCC BAA-894 5552532 YP_001440451.1 CDS ESA_pESA2p06582 NC_009779.1 24400 24627 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 24400..24627 Cronobacter sakazakii ATCC BAA-894 5552533 YP_001440452.1 CDS ESA_pESA2p06583 NC_009779.1 24639 25715 D COG: COG3704 Type IV secretory pathway, VirB6 components; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 24639..25715 Cronobacter sakazakii ATCC BAA-894 5552534 YP_001440453.1 CDS ESA_pESA2p06584 NC_009779.1 25793 25930 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 25793..25930 Cronobacter sakazakii ATCC BAA-894 5552519 YP_001440454.1 CDS ESA_pESA2p06585 NC_009779.1 25923 26606 D COG: COG3736 Type IV secretory pathway, component VirB8; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 25923..26606 Cronobacter sakazakii ATCC BAA-894 5552520 YP_001440455.1 CDS ESA_pESA2p06586 NC_009779.1 26603 27511 D COG: COG3504 Type IV secretory pathway, VirB9 components; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 26603..27511 Cronobacter sakazakii ATCC BAA-894 5552521 YP_001440456.1 CDS ESA_pESA2p06587 NC_009779.1 27554 28858 D COG: COG2948 Type IV secretory pathway, VirB10 components; Psort location: nuclear, score: 23; hypothetical protein 27554..28858 Cronobacter sakazakii ATCC BAA-894 5552522 YP_001440457.1 CDS ESA_pESA2p06588 NC_009779.1 28855 29880 D KEGG: reh:H16_A0983 1.5e-22 cpaF3; flp pilus assembly ATPase CpaF K01529; COG: COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; Psort location: cytoplasmic, score: 23; hypothetical protein 28855..29880 Cronobacter sakazakii ATCC BAA-894 5552523 YP_001440458.1 CDS ESA_pESA2p06589 NC_009779.1 29877 30275 D Psort location: extracellular, including cell wall, score: 9; ORF located using Blastx; hypothetical protein 29877..30275 Cronobacter sakazakii ATCC BAA-894 5552524 YP_001440459.1 CDS ESA_pESA2p06590 NC_009779.1 30302 30607 D COG: NOG33965 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 30302..30607 Cronobacter sakazakii ATCC BAA-894 5552525 YP_001440460.1 CDS ESA_pESA2p06591 NC_009779.1 30887 31192 D Psort location: nuclear, score: 23; hypothetical protein 30887..31192 Cronobacter sakazakii ATCC BAA-894 5552526 YP_001440461.1 CDS ESA_pESA3p05428 NC_009780.1 837 1574 D KEGG: rso:RSc0499 7.0e-21 gpmB, RS05023; putative phosphoglycerate mutase 2 protein K01834; COG: COG0406 Fructose-2,6-bisphosphatase; Psort location: cytoplasmic, score: 23; hypothetical protein 837..1574 Cronobacter sakazakii ATCC BAA-894 5552652 YP_001440462.1 CDS ESA_pESA3p05429 NC_009780.1 1673 2440 D COG: COG4705 Uncharacterized membrane-anchored protein conserved in bacteria; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 1673..2440 Cronobacter sakazakii ATCC BAA-894 5552660 YP_001440463.1 CDS ESA_pESA3p05430 NC_009780.1 2549 3622 D COG: NOG12552 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 2549..3622 Cronobacter sakazakii ATCC BAA-894 5552661 YP_001440464.1 CDS ESA_pESA3p05431 NC_009780.1 3627 4157 R KEGG: ddi:DDB0216844 7.6e-15 hypothetical protein K00676; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; hypothetical protein complement(3627..4157) Cronobacter sakazakii ATCC BAA-894 5552662 YP_001440465.1 CDS ESA_pESA3p05432 NC_009780.1 4454 5662 D KEGG: fal:FRAAL6580 1.8e-06 tmk; thymidylate kinase (dTMP kinase) (partial match) K00943; COG: NOG06507 non supervised orthologous group; Psort location: plasma membrane, score: 23; hypothetical protein 4454..5662 Cronobacter sakazakii ATCC BAA-894 5552572 YP_001440466.1 CDS ESA_pESA3p05433 NC_009780.1 5839 6090 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(5839..6090) Cronobacter sakazakii ATCC BAA-894 5552573 YP_001440467.1 CDS ESA_pESA3p05434 NC_009780.1 6101 6916 D outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 6101..6916 Cronobacter sakazakii ATCC BAA-894 5552574 YP_001440468.1 CDS ESA_pESA3p05435 NC_009780.1 7165 7707 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 7165..7707 Cronobacter sakazakii ATCC BAA-894 5552575 YP_001440469.1 CDS ESA_pESA3p05436 NC_009780.1 7704 8243 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 7704..8243 Cronobacter sakazakii ATCC BAA-894 5552564 YP_001440470.1 CDS ESA_pESA3p05437 NC_009780.1 8276 8971 D COG: COG2378 Predicted transcriptional regulator; Psort location: cytoplasmic, score: 23; hypothetical protein 8276..8971 Cronobacter sakazakii ATCC BAA-894 5552565 YP_001440471.1 CDS ESA_pESA3p05438 NC_009780.1 9028 9411 D COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: cytoplasmic, score: 23; hypothetical protein 9028..9411 Cronobacter sakazakii ATCC BAA-894 5552566 YP_001440472.1 CDS ESA_pESA3p05439 NC_009780.1 9465 10355 R COG: NOG11449 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(9465..10355) Cronobacter sakazakii ATCC BAA-894 5552567 YP_001440473.1 CDS ESA_pESA3p05440 NC_009780.1 10517 11287 R COG: COG3713 Outer membrane protein V; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(10517..11287) Cronobacter sakazakii ATCC BAA-894 5552552 YP_001440474.1 CDS ESA_pESA3p05441 NC_009780.1 11412 12104 D KEGG: rru:Rru_A2929 5.0e-50 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: cytoplasmic, score: 23; hypothetical protein 11412..12104 Cronobacter sakazakii ATCC BAA-894 5552553 YP_001440475.1 CDS ESA_pESA3p05442 NC_009780.1 12101 13279 D KEGG: xac:XAC2804 2.6e-85 baeS; two-component system sensor protein K07642; COG: COG0642 Signal transduction histidine kinase; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 12101..13279 Cronobacter sakazakii ATCC BAA-894 5552554 YP_001440476.1 CDS ESA_pESA3p05443 NC_009780.1 13373 14521 D KEGG: pat:Patl_1800 0.0026 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase K00658; COG: COG0845 Membrane-fusion protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 13373..14521 Cronobacter sakazakii ATCC BAA-894 5552555 YP_001440477.1 CDS ESA_pESA3p05444 NC_009780.1 14522 17572 D KEGG: eci:UTI89_C2351 2.0e-62 yegO; hypothetical protein YegO K07789; COG: COG0841 Cation/multidrug efflux pump; Psort location: plasma membrane, score: 23; hypothetical protein 14522..17572 Cronobacter sakazakii ATCC BAA-894 5552548 YP_001440478.1 CDS ESA_pESA3p05445 NC_009780.1 17564 17920 R COG: NOG16264 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(17564..17920) Cronobacter sakazakii ATCC BAA-894 5552549 YP_001440479.1 CDS ESA_pESA3p05446 NC_009780.1 18001 18411 R KEGG: gka:GK3067 1.4e-08 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01529; COG: NOG15944 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(18001..18411) Cronobacter sakazakii ATCC BAA-894 5552550 YP_001440480.1 CDS ESA_pESA3p05447 NC_009780.1 18594 19079 D COG: COG2318 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 18594..19079 Cronobacter sakazakii ATCC BAA-894 5552551 YP_001440481.1 CDS ESA_pESA3p05449 NC_009780.1 19120 20031 R COG: NOG08503 non supervised orthologous group; Psort location: plasma membrane, score: 23; hypothetical protein complement(19120..20031) Cronobacter sakazakii ATCC BAA-894 5552584 YP_001440482.1 CDS ESA_pESA3p05448 NC_009780.1 20030 20689 D KEGG: bha:BH3415 0.0098 NADH dehydrogenase K03885; COG: NOG16009 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 20030..20689 Cronobacter sakazakii ATCC BAA-894 5552586 YP_001440483.1 CDS ESA_pESA3p05450 NC_009780.1 20988 22295 D KEGG: cal:orf19.2425 1.0e-07 highly conserved hypothetical protein K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein 20988..22295 Cronobacter sakazakii ATCC BAA-894 5552585 YP_001440484.1 CDS ESA_pESA3p05451 NC_009780.1 22288 23094 D KEGG: fal:FRAAL3539 0.0073 putative oxidoreductase, NAD(P)-binding domain K00059; COG: COG0725 ABC-type molybdate transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 22288..23094 Cronobacter sakazakii ATCC BAA-894 5552587 YP_001440485.1 CDS ESA_pESA3p05452 NC_009780.1 23069 23968 R KEGG: shn:Shewana3_3435 1.2e-14 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(23069..23968) Cronobacter sakazakii ATCC BAA-894 5552568 YP_001440486.1 CDS ESA_pESA3p05453 NC_009780.1 24104 24424 R COG: NOG21364 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(24104..24424) Cronobacter sakazakii ATCC BAA-894 5552569 YP_001440487.1 CDS ESA_pESA3p05454 NC_009780.1 24448 25110 D COG: NOG18230 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 24448..25110 Cronobacter sakazakii ATCC BAA-894 5552570 YP_001440488.1 CDS ESA_pESA3p05455 NC_009780.1 25132 25443 D COG: NOG18299 non supervised orthologous group; Psort location: cytoskeletal, score: 9; hypothetical protein 25132..25443 Cronobacter sakazakii ATCC BAA-894 5552571 YP_001440489.1 CDS ESA_pESA3p05456 NC_009780.1 25478 26218 R KEGG: cvi:CV0835 2.9e-15 icc; 3',5'-cyclic-nucleotide phosphodiesterase K03651; COG: COG1409 Predicted phosphohydrolases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(25478..26218) Cronobacter sakazakii ATCC BAA-894 5552556 YP_001440490.1 CDS ESA_pESA3p05457 NC_009780.1 26280 26600 D Psort location: cytoplasmic, score: 23; hypothetical protein 26280..26600 Cronobacter sakazakii ATCC BAA-894 5552557 YP_001440491.1 CDS ESA_pESA3p05458 NC_009780.1 26352 26630 R COG: NOG23111 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(26352..26630) Cronobacter sakazakii ATCC BAA-894 5552558 YP_001440492.1 CDS ESA_pESA3p05459 NC_009780.1 26668 26967 R Psort location: nuclear, score: 23; hypothetical protein complement(26668..26967) Cronobacter sakazakii ATCC BAA-894 5552559 YP_001440493.1 CDS ESA_pESA3p05460 NC_009780.1 27134 27289 D Psort location: cytoplasmic, score: 23; hypothetical protein 27134..27289 Cronobacter sakazakii ATCC BAA-894 5552580 YP_001440494.1 CDS ESA_pESA3p05461 NC_009780.1 27137 27376 R Psort location: nuclear, score: 23; hypothetical protein complement(27137..27376) Cronobacter sakazakii ATCC BAA-894 5552581 YP_001440495.1 CDS ESA_pESA3p05462 NC_009780.1 27774 28994 D KEGG: shn:Shewana3_3829 3.3e-13 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: cytoplasmic, score: 23; hypothetical protein 27774..28994 Cronobacter sakazakii ATCC BAA-894 5552582 YP_001440496.1 CDS ESA_pESA3p05463 NC_009780.1 29229 29972 D KEGG: eci:UTI89_C3737 1.9e-07 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 29229..29972 Cronobacter sakazakii ATCC BAA-894 5552583 YP_001440497.1 CDS ESA_pESA3p05464 NC_009780.1 30051 31961 R KEGG: cps:CPS_1826 1.0e-05 torS; sensor protein TorS K07647; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(30051..31961) Cronobacter sakazakii ATCC BAA-894 5552588 YP_001440498.1 CDS ESA_pESA3p05465 NC_009780.1 32388 32780 D KEGG: vfi:VFA0660 1.1e-22 prolyl endopeptidase K01322; COG: NOG18075 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 32388..32780 Cronobacter sakazakii ATCC BAA-894 5552589 YP_001440499.1 CDS ESA_pESA3p05466 NC_009780.1 32818 33228 R KEGG: reh:H16_A0240 2.0e-07 acetyltransferase (GNAT) family K00680; COG: NOG16606 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(32818..33228) Cronobacter sakazakii ATCC BAA-894 5552590 YP_001440500.1 CDS ESA_pESA3p05467 NC_009780.1 33278 33454 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 33278..33454 Cronobacter sakazakii ATCC BAA-894 5552591 YP_001440501.1 CDS ESA_pESA3p05468 NC_009780.1 33435 33758 D COG: COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides; Psort location: cytoplasmic, score: 23; hypothetical protein 33435..33758 Cronobacter sakazakii ATCC BAA-894 5552576 YP_001440502.1 CDS ESA_pESA3p05469 NC_009780.1 33751 34149 D KEGG: afu:AF1672 5.1e-09 acetolactate synthase small subunit K01653; COG: NOG28140 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 33751..34149 Cronobacter sakazakii ATCC BAA-894 5552577 YP_001440503.1 CDS ESA_pESA3p05470 NC_009780.1 34122 34847 D KEGG: rru:Rru_A1450 7.7e-05 transcriptional regulator, ArsR family; COG: COG0640 Predicted transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein 34122..34847 Cronobacter sakazakii ATCC BAA-894 5552578 YP_001440504.1 CDS ESA_pESA3p05471 NC_009780.1 34929 35750 D KEGG: psb:Psyr_4478 3.7e-109 alpha/beta hydrolase fold K00433; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: endoplasmic reticulum, score: 23; hypothetical protein 34929..35750 Cronobacter sakazakii ATCC BAA-894 5552579 YP_001440505.1 CDS ESA_pESA3p05472 NC_009780.1 35797 37173 R KEGG: lwe:lwe0269 7.1e-99 PTS system, beta-glucoside-specific IIABC component K00890; COG: COG1264 Phosphotransferase system IIB components; Psort location: plasma membrane, score: 23; hypothetical protein complement(35797..37173) Cronobacter sakazakii ATCC BAA-894 5552544 YP_001440506.1 CDS ESA_pESA3p05473 NC_009780.1 37306 38652 D KEGG: eci:UTI89_C1768 4.6e-72 rspA; starvation sensing protein RspA K08323; COG: COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 37306..38652 Cronobacter sakazakii ATCC BAA-894 5552545 YP_001440507.1 CDS ESA_pESA3p05474 NC_009780.1 38640 39407 R KEGG: btk:BT9727_3183 2.8e-11 transcriptional regulator, GntR family; COG: COG2188 Transcriptional regulators; Psort location: cytoplasmic, score: 23; hypothetical protein complement(38640..39407) Cronobacter sakazakii ATCC BAA-894 5552546 YP_001440508.1 CDS ESA_pESA3p05475 NC_009780.1 39555 39848 R KEGG: ape:APE_0256a.1 0.00024 DNA-directed RNA polymerase,subunit E K03050; COG: COG2314 Predicted membrane protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(39555..39848) Cronobacter sakazakii ATCC BAA-894 5552547 YP_001440509.1 CDS ESA_pESA3p05476 NC_009780.1 39966 40334 D COG: NOG23795 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 39966..40334 Cronobacter sakazakii ATCC BAA-894 5552540 YP_001440510.1 CDS ESA_pESA3p05477 NC_009780.1 39990 40247 R Psort location: mitochondrial, score: 23; hypothetical protein complement(39990..40247) Cronobacter sakazakii ATCC BAA-894 5552541 YP_001440511.1 CDS ESA_pESA3p05478 NC_009780.1 40484 42061 D KEGG: ava:Ava_1030 3.1e-31 putative diguanylate cyclase (GGDEF domain) K02488; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 40484..42061 Cronobacter sakazakii ATCC BAA-894 5552542 YP_001440512.1 CDS ESA_pESA3p05479 NC_009780.1 42144 42989 R KEGG: bms:BR0643 0.0028 transglycosylase SLT domain protein K01238; Psort location: nuclear, score: 23; hypothetical protein complement(42144..42989) Cronobacter sakazakii ATCC BAA-894 5552543 YP_001440513.1 CDS ESA_pESA3p05480 NC_009780.1 43179 43424 D Psort location: cytoplasmic, score: 23; hypothetical protein 43179..43424 Cronobacter sakazakii ATCC BAA-894 5552560 YP_001440514.1 CDS ESA_pESA3p05481 NC_009780.1 43387 43995 D COG: COG3157 Hemolysin-coregulated protein (uncharacterized); Psort location: mitochondrial, score: 23; hypothetical protein 43387..43995 Cronobacter sakazakii ATCC BAA-894 5552561 YP_001440515.1 CDS ESA_pESA3p05482 NC_009780.1 44014 44952 D Psort location: endoplasmic reticulum, score: 23; hypothetical protein 44014..44952 Cronobacter sakazakii ATCC BAA-894 5552562 YP_001440516.1 CDS ESA_pESA3p05483 NC_009780.1 45174 45500 D KEGG: mmp:MMP1692 0.0084 vhuB; polyferredoxin, associated with F420-non-reducing hydrogenase; COG: COG1145 Ferredoxin; Psort location: nuclear, score: 23; hypothetical protein 45174..45500 Cronobacter sakazakii ATCC BAA-894 5552563 YP_001440517.1 CDS ESA_pESA3p05484 NC_009780.1 45722 47098 D KEGG: shn:Shewana3_0031 2.9e-63 potassium uptake protein, TrkH family K00961; COG: COG0168 Trk-type K+ transport systems, membrane components; Psort location: plasma membrane, score: 23; hypothetical protein 45722..47098 Cronobacter sakazakii ATCC BAA-894 5552592 YP_001440518.1 CDS ESA_pESA3p05485 NC_009780.1 47151 47564 R KEGG: ecj:JW3470 3.9e-50 arsC; arsenate reductase K00537; COG: COG1393 Arsenate reductase and related proteins, glutaredoxin family; Psort location: nuclear, score: 23; hypothetical protein complement(47151..47564) Cronobacter sakazakii ATCC BAA-894 5552593 YP_001440519.1 CDS ESA_pESA3p05486 NC_009780.1 47609 48892 R KEGG: ecj:JW3469 1.1e-180 arsB; arsenite/antimonite transporter K03893; COG: COG1055 Na+/H+ antiporter NhaD and related arsenite permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(47609..48892) Cronobacter sakazakii ATCC BAA-894 5552594 YP_001440520.1 CDS ESA_pESA3p05487 NC_009780.1 48980 49315 R KEGG: rru:Rru_A1450 2.0e-13 transcriptional regulator, ArsR family; COG: COG0640 Predicted transcriptional regulators; Psort location: nuclear, score: 23; hypothetical protein complement(48980..49315) Cronobacter sakazakii ATCC BAA-894 5552595 YP_001440521.1 CDS ESA_pESA3p05488 NC_009780.1 49405 50292 R KEGG: plu:plu1530 2.6e-78 unnamed protein product; similar to dihydrodipicolinate synthetase K01714; COG: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(49405..50292) Cronobacter sakazakii ATCC BAA-894 5552608 YP_001440522.1 CDS ESA_pESA3p05489 NC_009780.1 50317 51222 R COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(50317..51222) Cronobacter sakazakii ATCC BAA-894 5552609 YP_001440523.1 CDS ESA_pESA3p05490 NC_009780.1 51287 52621 D KEGG: reh:H16_B1957 2.9e-125 transcriptional regulator, MocR family; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: cytoplasmic, score: 23; hypothetical protein 51287..52621 Cronobacter sakazakii ATCC BAA-894 5552610 YP_001440524.1 CDS ESA_pESA3p05491 NC_009780.1 53314 53811 D COG: COG3516 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 53314..53811 Cronobacter sakazakii ATCC BAA-894 5552611 YP_001440525.1 CDS ESA_pESA3p05492 NC_009780.1 53846 55387 D KEGG: bpm:BURPS1710b_A0534 3.0e-116 hypothetical protein K00356; COG: COG3517 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 53846..55387 Cronobacter sakazakii ATCC BAA-894 5552628 YP_001440526.1 CDS ESA_pESA3p05493 NC_009780.1 55398 56738 D COG: COG3522 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 55398..56738 Cronobacter sakazakii ATCC BAA-894 5552629 YP_001440527.1 CDS ESA_pESA3p05494 NC_009780.1 56735 57388 D COG: COG3455 Uncharacterized protein conserved in bacteria; Psort location: vesicles of secretory system, score: 9; hypothetical protein 56735..57388 Cronobacter sakazakii ATCC BAA-894 5552630 YP_001440528.1 CDS ESA_pESA3p05495 NC_009780.1 57392 59095 D KEGG: bma:BMA3197 0.0051 coxB; cytochrome c oxidase, subunit II K02275; COG: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Psort location: golgi, score: 9; hypothetical protein 57392..59095 Cronobacter sakazakii ATCC BAA-894 5552631 YP_001440529.1 CDS ESA_pESA3p05496 NC_009780.1 59110 59601 D COG: COG3157 Hemolysin-coregulated protein (uncharacterized); Psort location: cytoplasmic, score: 23; hypothetical protein 59110..59601 Cronobacter sakazakii ATCC BAA-894 5552620 YP_001440530.1 CDS ESA_pESA3p05497 NC_009780.1 59747 62413 D KEGG: eci:UTI89_C3197 0. ClpB protein K01358; COG: COG0542 ATPases with chaperone activity, ATP-binding subunit; Psort location: cytoplasmic, score: 23; hypothetical protein 59747..62413 Cronobacter sakazakii ATCC BAA-894 5552621 YP_001440531.1 CDS ESA_pESA3p05498 NC_009780.1 62579 62959 D COG: COG4253 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 62579..62959 Cronobacter sakazakii ATCC BAA-894 5552622 YP_001440532.1 CDS ESA_pESA3p05499 NC_009780.1 63454 63639 D Psort location: cytoplasmic, score: 23; hypothetical protein 63454..63639 Cronobacter sakazakii ATCC BAA-894 5552623 YP_001440533.1 CDS ESA_pESA3p05500 NC_009780.1 63673 66615 D KEGG: saz:Sama_1205 3.3e-06 peptidyl-Lys metalloendopeptidase K08646; COG: COG3501 Uncharacterized protein conserved in bacteria; Psort location: cytoplasmic, score: 23; hypothetical protein 63673..66615 Cronobacter sakazakii ATCC BAA-894 5552600 YP_001440534.1 CDS ESA_pESA3p05502 NC_009780.1 66545 66670 R Psort location: nuclear, score: 23; hypothetical protein complement(66545..66670) Cronobacter sakazakii ATCC BAA-894 5552601 YP_001440535.1 CDS ESA_pESA3p05501 NC_009780.1 66612 67292 D Psort location: extracellular, including cell wall, score: 9; hypothetical protein 66612..67292 Cronobacter sakazakii ATCC BAA-894 5552603 YP_001440536.1 CDS ESA_pESA3p05503 NC_009780.1 67387 68034 D COG: NOG36642 non supervised orthologous group; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 67387..68034 Cronobacter sakazakii ATCC BAA-894 5552602 YP_001440537.1 CDS ESA_pESA3p05504 NC_009780.1 68104 68370 D COG: COG4104 Uncharacterized conserved protein; Psort location: vesicles of secretory system, score: 9; ORF located using Blastx; hypothetical protein 68104..68370 Cronobacter sakazakii ATCC BAA-894 5552616 YP_001440538.1 CDS ESA_pESA3p05505 NC_009780.1 68512 69198 D Psort location: cytoplasmic, score: 23; hypothetical protein 68512..69198 Cronobacter sakazakii ATCC BAA-894 5552617 YP_001440539.1 CDS ESA_pESA3p05506 NC_009780.1 69230 69553 D COG: COG3521 Uncharacterized protein conserved in bacteria; Psort location: nuclear, score: 23; hypothetical protein 69230..69553 Cronobacter sakazakii ATCC BAA-894 5552618 YP_001440540.1 CDS ESA_pESA3p05507 NC_009780.1 69587 70336 R KEGG: eci:UTI89_C0607 5.4e-69 dsbG; thiol:disulfide interchange protein DsbG precursor K03805; COG: COG1651 Protein-disulfide isomerase; Psort location: extracellular, including cell wall, score: 23; hypothetical protein complement(69587..70336) Cronobacter sakazakii ATCC BAA-894 5552619 YP_001440541.1 CDS ESA_pESA3p05508 NC_009780.1 70333 72354 R KEGG: xoo:XOO0561 4.3e-60 dsbD; C-type cytochrome biogenesis protein (copper tolerance) K04084; COG: COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(70333..72354) Cronobacter sakazakii ATCC BAA-894 5552636 YP_001440542.1 CDS ESA_pESA3p05509 NC_009780.1 72401 72790 R COG: NOG29928 non supervised orthologous group; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(72401..72790) Cronobacter sakazakii ATCC BAA-894 5552637 YP_001440543.1 CDS ESA_pESA3p05510 NC_009780.1 72904 73233 R Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(72904..73233) Cronobacter sakazakii ATCC BAA-894 5552638 YP_001440544.1 CDS ESA_pESA3p05512 NC_009780.1 73420 73812 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(73420..73812) Cronobacter sakazakii ATCC BAA-894 5552639 YP_001440545.1 CDS ESA_pESA3p05511 NC_009780.1 73492 73881 D Psort location: cytoplasmic, score: 23; hypothetical protein 73492..73881 Cronobacter sakazakii ATCC BAA-894 5552537 YP_001440546.1 CDS ESA_pESA3p05513 NC_009780.1 74005 74505 D Psort location: cytoplasmic, score: 23; hypothetical protein 74005..74505 Cronobacter sakazakii ATCC BAA-894 5552536 YP_001440547.1 CDS ESA_pESA3p05515 NC_009780.1 74569 74724 R Psort location: mitochondrial, score: 23; hypothetical protein complement(74569..74724) Cronobacter sakazakii ATCC BAA-894 5552538 YP_001440548.1 CDS ESA_pESA3p05514 NC_009780.1 74623 74868 D COG: NOG13879 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 74623..74868 Cronobacter sakazakii ATCC BAA-894 5552596 YP_001440549.1 CDS ESA_pESA3p05516 NC_009780.1 74943 75701 R KEGG: ret:RHE_PF00271 1.3e-90 probable iron ABC transporter, ATP-binding protein K02013; COG: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; Psort location: cytoplasmic, score: 23; hypothetical protein complement(74943..75701) Cronobacter sakazakii ATCC BAA-894 5552539 YP_001440550.1 CDS ESA_pESA3p05517 NC_009780.1 75698 76738 R COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: endoplasmic reticulum, score: 23; hypothetical protein complement(75698..76738) Cronobacter sakazakii ATCC BAA-894 5552597 YP_001440551.1 CDS ESA_pESA3p05518 NC_009780.1 76738 77751 R COG: COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; Psort location: extracellular, including cell wall, score: 9; hypothetical protein complement(76738..77751) Cronobacter sakazakii ATCC BAA-894 5552598 YP_001440552.1 CDS ESA_pESA3p05519 NC_009780.1 77985 79220 D KEGG: gsu:GSU3029 1.5e-11 long-chain-fatty-acid--[acyl-carrier-protein] ligase / acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase K05939:K01909; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: endoplasmic reticulum, score: 9; hypothetical protein 77985..79220 Cronobacter sakazakii ATCC BAA-894 5552599 YP_001440553.1 CDS ESA_pESA3p05520 NC_009780.1 80515 81492 D COG: COG4974 Site-specific recombinase XerD; Psort location: cytoplasmic, score: 23; hypothetical protein 80515..81492 Cronobacter sakazakii ATCC BAA-894 5552624 YP_001440554.1 CDS ESA_pESA3p05521 NC_009780.1 81587 82810 D COG: NOG28530 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 81587..82810 Cronobacter sakazakii ATCC BAA-894 5552625 YP_001440555.1 CDS ESA_pESA3p05522 NC_009780.1 82804 84621 D COG: NOG28669 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 82804..84621 Cronobacter sakazakii ATCC BAA-894 5552626 YP_001440556.1 CDS ESA_pESA3p05523 NC_009780.1 84614 87775 D KEGG: psb:Psyr_3842 0.00023 SNF2-related:helicase, C-terminal:type III restriction enzyme, res subunit K03580; COG: NOG25072 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein 84614..87775 Cronobacter sakazakii ATCC BAA-894 5552627 YP_001440557.1 CDS ESA_pESA3p05524 NC_009780.1 87782 88456 R KEGG: pen:PSEEN0676 3.0e-43 oxidoreductase, short chain dehydrogenase/reductase family; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: cytoplasmic, score: 23; hypothetical protein complement(87782..88456) Cronobacter sakazakii ATCC BAA-894 5552644 YP_001440558.1 CDS ESA_pESA3p05525 NC_009780.1 88503 89072 R COG: NOG17257 non supervised orthologous group; Psort location: cytoplasmic, score: 23; hypothetical protein complement(88503..89072) Cronobacter sakazakii ATCC BAA-894 5552645 YP_001440559.1 CDS ESA_pESA3p05526 NC_009780.1 89085 89354 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(89085..89354) Cronobacter sakazakii ATCC BAA-894 5552646 YP_001440560.1 CDS ESA_pESA3p05527 NC_009780.1 89638 91275 R KEGG: lpl:lp_3093 2.3e-05 muramidase (putative) K01185; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: plasma membrane, score: 23; hypothetical protein complement(89638..91275) Cronobacter sakazakii ATCC BAA-894 5552647 YP_001440561.1 CDS ESA_pESA3p05528 NC_009780.1 91455 92390 D KEGG: rha:RHA1_ro06806 4.5e-07 probable hydroxyacylglutathione hydrolase K01069; COG: NOG09919 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein 91455..92390 Cronobacter sakazakii ATCC BAA-894 5552604 YP_001440562.1 CDS ESA_pESA3p05529 NC_009780.1 92411 93730 R Catalyzes the deamination of guanine; guanine deaminase complement(92411..93730) Cronobacter sakazakii ATCC BAA-894 5552605 YP_001440563.1 CDS ESA_pESA3p05530 NC_009780.1 94310 94906 D KEGG: bur:Bcep18194_B2557 6.5e-25 glutathione S-transferase-like K00799; COG: COG0625 glutathione S-transferase; Psort location: cytoplasmic, score: 23; hypothetical protein 94310..94906 Cronobacter sakazakii ATCC BAA-894 5552606 YP_001440564.1 CDS ESA_pESA3p05531 NC_009780.1 94946 95272 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(94946..95272) Cronobacter sakazakii ATCC BAA-894 5552607 YP_001440565.1 CDS ESA_pESA3p05532 NC_009780.1 95571 97553 R KEGG: mma:MM2965 4.1e-21 hypothetical sensory transduction histidine kinase; COG: COG0840 Methyl-accepting chemotaxis protein; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(95571..97553) Cronobacter sakazakii ATCC BAA-894 5552648 YP_001440566.1 CDS ESA_pESA3p05533 NC_009780.1 97878 98648 R KEGG: ama:AM949 8.6e-08 clpB; ATP-dependent clp protease ATP-binding subunit K03695; COG: COG0542 ATPases with chaperone activity, ATP-binding subunit; Psort location: cytoplasmic, score: 23; hypothetical protein complement(97878..98648) Cronobacter sakazakii ATCC BAA-894 5552649 YP_001440567.1 CDS ESA_pESA3p05534 NC_009780.1 99094 99234 D Psort location: nuclear, score: 23; hypothetical protein 99094..99234 Cronobacter sakazakii ATCC BAA-894 5552650 YP_001440568.1 CDS ESA_pESA3p05535 NC_009780.1 99219 100403 R COG: COG0814 Amino acid permeases; Psort location: plasma membrane, score: 23; hypothetical protein complement(99219..100403) Cronobacter sakazakii ATCC BAA-894 5552651 YP_001440569.1 CDS ESA_pESA3p05536 NC_009780.1 100683 103397 R KEGG: stm:STM3763 0. mgtB; Mg2+ transport protein K01531; COG: COG0474 Cation transport ATPase; Psort location: plasma membrane, score: 23; hypothetical protein complement(100683..103397) Cronobacter sakazakii ATCC BAA-894 5552640 YP_001440570.1 CDS ESA_pESA3p05537 NC_009780.1 103965 105086 R COG: COG2850 Uncharacterized conserved protein; Psort location: cytoplasmic, score: 23; hypothetical protein complement(103965..105086) Cronobacter sakazakii ATCC BAA-894 5552641 YP_001440571.1 CDS ESA_pESA3p05538 NC_009780.1 105236 105403 D Psort location: nuclear, score: 23; hypothetical protein 105236..105403 Cronobacter sakazakii ATCC BAA-894 5552642 YP_001440572.1 CDS ESA_pESA3p05539 NC_009780.1 105528 108467 D KEGG: chu:CHU_0837 2.4e-16 CHU large protein; uncharacterized K01238; COG: COG2931 RTX toxins and related Ca2+-binding proteins; Psort location: extracellular, including cell wall, score: 9; hypothetical protein 105528..108467 Cronobacter sakazakii ATCC BAA-894 5552643 YP_001440573.1 CDS ESA_pESA3p05540 NC_009780.1 108529 110646 R KEGG: stm:STM1558 0. putative glycosyl hydrolase K02438; COG: COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Psort location: cytoplasmic, score: 23; hypothetical protein complement(108529..110646) Cronobacter sakazakii ATCC BAA-894 5552632 YP_001440574.1 CDS ESA_pESA3p05541 NC_009780.1 110673 113204 R KEGG: ret:RHE_PE00008 2.2e-207 putative maltooligosyl trehalose synthase protein; COG: COG3280 Maltooligosyl trehalose synthase; Psort location: cytoplasmic, score: 23; hypothetical protein complement(110673..113204) Cronobacter sakazakii ATCC BAA-894 5552633 YP_001440575.1 CDS ESA_pESA3p05542 NC_009780.1 113201 114985 R KEGG: sme:SMb21447 4.3e-147 glgB2; putative 1,4-alpha-glucan branching enzyme protein K00700; COG: COG0296 1,4-alpha-glucan branching enzyme; Psort location: endoplasmic reticulum, score: 9; hypothetical protein complement(113201..114985) Cronobacter sakazakii ATCC BAA-894 5552634 YP_001440576.1 CDS ESA_pESA3p05543 NC_009780.1 115291 116580 R COG: COG3550 Uncharacterized protein related to capsule biosynthesis enzymes; Psort location: cytoplasmic, score: 23; hypothetical protein complement(115291..116580) Cronobacter sakazakii ATCC BAA-894 5552635 YP_001440577.1 CDS ESA_pESA3p05544 NC_009780.1 116613 116894 R KEGG: afu:AF2118 0.0061 guaB-2; IMP dehydrogenase K00088; COG: NOG36203 non supervised orthologous group; Psort location: mitochondrial, score: 23; hypothetical protein complement(116613..116894) Cronobacter sakazakii ATCC BAA-894 5552612 YP_001440578.1 CDS ESA_pESA3p05545 NC_009780.1 117025 117909 R COG: COG2375 Siderophore-interacting protein; Psort location: mitochondrial, score: 23; hypothetical protein complement(117025..117909) Cronobacter sakazakii ATCC BAA-894 5552613 YP_001440579.1 CDS ESA_pESA3p05546 NC_009780.1 117906 119117 R COG: COG0477 Permeases of the major facilitator superfamily; Psort location: plasma membrane, score: 23; hypothetical protein complement(117906..119117) Cronobacter sakazakii ATCC BAA-894 5552614 YP_001440580.1 CDS ESA_pESA3p05547 NC_009780.1 119253 121001 D KEGG: yps:YPTB3263 5.6e-225 rhbC, iucA; possible siderophore biosynthesis protein, IucA familly K03894; COG: COG4264 Siderophore synthetase component; Psort location: cytoplasmic, score: 23; hypothetical protein 119253..121001 Cronobacter sakazakii ATCC BAA-894 5552615 YP_001440581.1 CDS ESA_pESA3p05548 NC_009780.1 120991 121941 D KEGG: yps:YPTB3264 9.9e-125 iucB; putative siderophore biosynthesis protein IucB K03896; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: cytoplasmic, score: 23; hypothetical protein 120991..121941 Cronobacter sakazakii ATCC BAA-894 5552653 YP_001440582.1 CDS ESA_pESA3p05549 NC_009780.1 121938 123683 D KEGG: yps:YPTB3265 4.1e-229 iucC; putative siderophore biosynthesis protein IucC K03895; COG: COG4264 Siderophore synthetase component; Psort location: cytoplasmic, score: 23; hypothetical protein 121938..123683 Cronobacter sakazakii ATCC BAA-894 5552654 YP_001440583.1 CDS ESA_pESA3p05550 NC_009780.1 123680 125002 D KEGG: yps:YPTB3266 3.5e-161 iucD; putative siderophore biosynthesis protein IucD K03897; COG: COG3486 Lysine/ornithine N-monooxygenase; Psort location: cytoplasmic, score: 23; hypothetical protein 123680..125002 Cronobacter sakazakii ATCC BAA-894 5552655 YP_001440584.1 CDS ESA_pESA3p05551 NC_009780.1 125070 127220 D COG: COG1629 Outer membrane receptor proteins, mostly Fe transport; Psort location: cytoplasmic, score: 23; hypothetical protein 125070..127220 Cronobacter sakazakii ATCC BAA-894 5552656 YP_001440585.1 CDS ESA_pESA3p05552 NC_009780.1 127386 127520 R Psort location: cytoplasmic, score: 23; hypothetical protein complement(127386..127520) Cronobacter sakazakii ATCC BAA-894 5552657 YP_001440586.1 CDS ESA_pESA3p05553 NC_009780.1 127747 128715 R COG: COG1475 Predicted transcriptional regulators; Psort location: mitochondrial, score: 23; hypothetical protein complement(127747..128715) Cronobacter sakazakii ATCC BAA-894 5552658 YP_001440587.1 CDS ESA_pESA3p05554 NC_009780.1 128723 129922 R KEGG: pha:PSHAa0816 6.4e-10 partitioning protein A K00903; COG: COG1192 ATPases involved in chromosome partitioning; Psort location: cytoplasmic, score: 23; hypothetical protein complement(128723..129922) Cronobacter sakazakii ATCC BAA-894 5552659 ESA_00048 tRNA ESA_00048 NC_009778.1 26515 26588 D tRNA-Ile 26515..26588 Cronobacter sakazakii ATCC BAA-894 5549103 ESA_00049 tRNA ESA_00049 NC_009778.1 26703 26775 D tRNA-Ala 26703..26775 Cronobacter sakazakii ATCC BAA-894 5549124 ESA_00146 tRNA ESA_00146 NC_009778.1 133135 133207 R tRNA-Phe complement(133135..133207) Cronobacter sakazakii ATCC BAA-894 5552492 ESA_00172 tRNA ESA_00172 NC_009778.1 157866 157938 D tRNA-Gly 157866..157938 Cronobacter sakazakii ATCC BAA-894 5549142 ESA_00173 tRNA ESA_00173 NC_009778.1 157976 158048 D tRNA-Gly 157976..158048 Cronobacter sakazakii ATCC BAA-894 5549086 ESA_00174 tRNA ESA_00174 NC_009778.1 158085 158157 D tRNA-Gly 158085..158157 Cronobacter sakazakii ATCC BAA-894 5549162 ESA_00311 tRNA ESA_00311 NC_009778.1 287435 287507 R tRNA-Phe complement(287435..287507) Cronobacter sakazakii ATCC BAA-894 5552308 ESA_00352 tRNA ESA_00352 NC_009778.1 324788 324860 R tRNA-Met complement(324788..324860) Cronobacter sakazakii ATCC BAA-894 5549642 ESA_00444 tRNA ESA_00444 NC_009778.1 419832 419902 D tRNA-Gly 419832..419902 Cronobacter sakazakii ATCC BAA-894 5549833 ESA_00495 tRNA ESA_00495 NC_009778.1 472501 472574 R tRNA-Met complement(472501..472574) Cronobacter sakazakii ATCC BAA-894 5551927 ESA_00496 tRNA ESA_00496 NC_009778.1 472619 472692 R tRNA-Met complement(472619..472692) Cronobacter sakazakii ATCC BAA-894 5552041 ESA_00572 tRNA ESA_00572 NC_009778.1 545730 545819 D tRNA-Ser 545730..545819 Cronobacter sakazakii ATCC BAA-894 5551685 ESA_00573 tRNA ESA_00573 NC_009778.1 545827 545900 D tRNA-Arg 545827..545900 Cronobacter sakazakii ATCC BAA-894 5551708 ESA_00574 tRNA ESA_00574 NC_009778.1 545966 546039 D tRNA-Arg 545966..546039 Cronobacter sakazakii ATCC BAA-894 5551636 ESA_00575 tRNA ESA_00575 NC_009778.1 546235 546308 D tRNA-Arg 546235..546308 Cronobacter sakazakii ATCC BAA-894 5551682 ESA_00576 tRNA ESA_00576 NC_009778.1 546374 546447 D tRNA-Arg 546374..546447 Cronobacter sakazakii ATCC BAA-894 5551653 ESA_00664 tRNA ESA_00664 NC_009778.1 631378 631451 D tRNA-Ile 631378..631451 Cronobacter sakazakii ATCC BAA-894 5551286 ESA_00665 tRNA ESA_00665 NC_009778.1 631488 631560 D tRNA-Ala 631488..631560 Cronobacter sakazakii ATCC BAA-894 5551285 ESA_00837 tRNA ESA_00837 NC_009778.1 810614 810686 R tRNA-Lys complement(810614..810686) Cronobacter sakazakii ATCC BAA-894 5550373 ESA_00838 tRNA ESA_00838 NC_009778.1 810694 810766 R tRNA-Val complement(810694..810766) Cronobacter sakazakii ATCC BAA-894 5550416 ESA_00839 tRNA ESA_00839 NC_009778.1 810818 810890 R tRNA-Val complement(810818..810890) Cronobacter sakazakii ATCC BAA-894 5550370 ESA_00840 tRNA ESA_00840 NC_009778.1 810934 811006 R tRNA-Val complement(810934..811006) Cronobacter sakazakii ATCC BAA-894 5550503 ESA_00844 tRNA ESA_00844 NC_009778.1 813681 813753 D tRNA-Ala 813681..813753 Cronobacter sakazakii ATCC BAA-894 5550495 ESA_00845 tRNA ESA_00845 NC_009778.1 813801 813873 D tRNA-Ala 813801..813873 Cronobacter sakazakii ATCC BAA-894 5550552 ESA_00866 tRNA ESA_00866 NC_009778.1 837242 837313 R tRNA-Arg complement(837242..837313) Cronobacter sakazakii ATCC BAA-894 5550816 ESA_04409 tRNA ESA_04409 NC_009778.1 969656 969733 R tRNA-Pro complement(969656..969733) Cronobacter sakazakii ATCC BAA-894 9679597 ESA_01047 tRNA ESA_01047 NC_009778.1 1009913 1009986 R tRNA-Pro complement(1009913..1009986) Cronobacter sakazakii ATCC BAA-894 5548431 ESA_01213 tRNA ESA_01213 NC_009778.1 1181722 1181794 R tRNA-Asn complement(1181722..1181794) Cronobacter sakazakii ATCC BAA-894 5548695 ESA_01219 tRNA ESA_01219 NC_009778.1 1190130 1190202 R tRNA-Asn complement(1190130..1190202) Cronobacter sakazakii ATCC BAA-894 5548825 ESA_01223 tRNA ESA_01223 NC_009778.1 1194646 1194718 R tRNA-Asn complement(1194646..1194718) Cronobacter sakazakii ATCC BAA-894 5548717 ESA_01227 tRNA ESA_01227 NC_009778.1 1198640 1198712 R tRNA-Asn complement(1198640..1198712) Cronobacter sakazakii ATCC BAA-894 5548986 ESA_01229 tRNA ESA_01229 NC_009778.1 1199705 1199791 D tRNA-Ser 1199705..1199791 Cronobacter sakazakii ATCC BAA-894 5548712 ESA_01312 tRNA ESA_01312 NC_009778.1 1272530 1272602 D tRNA-Gly 1272530..1272602 Cronobacter sakazakii ATCC BAA-894 5552339 ESA_04410 tRNA ESA_04410 NC_009778.1 1272660 1272733 D tRNA-Cys 1272660..1272733 Cronobacter sakazakii ATCC BAA-894 9679598 ESA_01313 tRNA ESA_01313 NC_009778.1 1272745 1272828 D tRNA-Leu 1272745..1272828 Cronobacter sakazakii ATCC BAA-894 5550702 ESA_01526 tRNA ESA_01526 NC_009778.1 1477126 1477207 R tRNA-Tyr complement(1477126..1477207) Cronobacter sakazakii ATCC BAA-894 5548090 ESA_01528 tRNA ESA_01528 NC_009778.1 1477422 1477503 R tRNA-Tyr complement(1477422..1477503) Cronobacter sakazakii ATCC BAA-894 5549531 ESA_02029 tRNA ESA_02029 NC_009778.1 1963902 1963975 D tRNA-Val 1963902..1963975 Cronobacter sakazakii ATCC BAA-894 5549877 ESA_02030 tRNA ESA_02030 NC_009778.1 1963988 1964061 D tRNA-Val 1963988..1964061 Cronobacter sakazakii ATCC BAA-894 5552446 ESA_02346 tRNA ESA_02346 NC_009778.1 2279690 2279774 D tRNA-Ser 2279690..2279774 Cronobacter sakazakii ATCC BAA-894 5551250 ESA_02348 tRNA ESA_02348 NC_009778.1 2282784 2282868 D tRNA-Ser 2282784..2282868 Cronobacter sakazakii ATCC BAA-894 5551239 ESA_02377 tRNA ESA_02377 NC_009778.1 2311040 2311124 R tRNA-Ser complement(2311040..2311124) Cronobacter sakazakii ATCC BAA-894 5551089 ESA_02597 tRNA ESA_02597 NC_009778.1 2550071 2550143 R tRNA-Lys complement(2550071..2550143) Cronobacter sakazakii ATCC BAA-894 5550849 ESA_02598 tRNA ESA_02598 NC_009778.1 2550243 2550315 R tRNA-Lys complement(2550243..2550315) Cronobacter sakazakii ATCC BAA-894 5550759 ESA_02599 tRNA ESA_02599 NC_009778.1 2550397 2550469 R tRNA-Lys complement(2550397..2550469) Cronobacter sakazakii ATCC BAA-894 5550835 ESA_02600 tRNA ESA_02600 NC_009778.1 2550476 2550548 R tRNA-Val complement(2550476..2550548) Cronobacter sakazakii ATCC BAA-894 5550793 ESA_02601 tRNA ESA_02601 NC_009778.1 2550659 2550731 R tRNA-Lys complement(2550659..2550731) Cronobacter sakazakii ATCC BAA-894 5550810 ESA_02666 tRNA ESA_02666 NC_009778.1 2622017 2622090 D tRNA-Met 2622017..2622090 Cronobacter sakazakii ATCC BAA-894 5550544 ESA_02667 tRNA ESA_02667 NC_009778.1 2622102 2622183 D tRNA-Leu 2622102..2622183 Cronobacter sakazakii ATCC BAA-894 5550538 ESA_02668 tRNA ESA_02668 NC_009778.1 2622209 2622280 D tRNA-Gln 2622209..2622280 Cronobacter sakazakii ATCC BAA-894 5550547 ESA_02669 tRNA ESA_02669 NC_009778.1 2622320 2622391 D tRNA-Gln 2622320..2622391 Cronobacter sakazakii ATCC BAA-894 5550488 ESA_02670 tRNA ESA_02670 NC_009778.1 2622425 2622498 D tRNA-Met 2622425..2622498 Cronobacter sakazakii ATCC BAA-894 5550514 ESA_02672 tRNA ESA_02672 NC_009778.1 2622564 2622635 D tRNA-Gln 2622564..2622635 Cronobacter sakazakii ATCC BAA-894 5550505 ESA_02673 tRNA ESA_02673 NC_009778.1 2622730 2622801 D tRNA-Gln 2622730..2622801 Cronobacter sakazakii ATCC BAA-894 5550487 ESA_02755 tRNA ESA_02755 NC_009778.1 2701466 2701539 R tRNA-Arg complement(2701466..2701539) Cronobacter sakazakii ATCC BAA-894 5550340 ESA_03108 tRNA ESA_03108 NC_009778.1 3025398 3025470 R tRNA-Thr complement(3025398..3025470) Cronobacter sakazakii ATCC BAA-894 5552426 ESA_03123 tRNA ESA_03123 NC_009778.1 3040743 3040816 R tRNA-Asp complement(3040743..3040816) Cronobacter sakazakii ATCC BAA-894 5549244 ESA_03133 tRNA ESA_03133 NC_009778.1 3048943 3049016 R tRNA-Asp complement(3048943..3049016) Cronobacter sakazakii ATCC BAA-894 5549691 ESA_03136 tRNA ESA_03136 NC_009778.1 3052387 3052459 R tRNA-Glu complement(3052387..3052459) Cronobacter sakazakii ATCC BAA-894 5549419 ESA_03382 tRNA ESA_03382 NC_009778.1 3322405 3322487 D tRNA-Leu 3322405..3322487 Cronobacter sakazakii ATCC BAA-894 5551021 ESA_03383 tRNA ESA_03383 NC_009778.1 3322523 3322605 D tRNA-Leu 3322523..3322605 Cronobacter sakazakii ATCC BAA-894 5551003 ESA_03384 tRNA ESA_03384 NC_009778.1 3322639 3322721 D tRNA-Leu 3322639..3322721 Cronobacter sakazakii ATCC BAA-894 5550990 ESA_03435 tRNA ESA_03435 NC_009778.1 3378091 3378172 R tRNA-Leu complement(3378091..3378172) Cronobacter sakazakii ATCC BAA-894 5549494 ESA_03564 tRNA ESA_03564 NC_009778.1 3504696 3504769 R tRNA-Met complement(3504696..3504769) Cronobacter sakazakii ATCC BAA-894 5552028 ESA_03565 tRNA ESA_03565 NC_009778.1 3504832 3504915 R tRNA-Leu complement(3504832..3504915) Cronobacter sakazakii ATCC BAA-894 5549614 ESA_03664 tRNA ESA_03664 NC_009778.1 3604275 3604347 R tRNA-Thr complement(3604275..3604347) Cronobacter sakazakii ATCC BAA-894 5550439 ESA_03668 tRNA ESA_03668 NC_009778.1 3607678 3607750 R tRNA-Glu complement(3607678..3607750) Cronobacter sakazakii ATCC BAA-894 5551692 ESA_03700 tRNA ESA_03700 NC_009778.1 3640439 3640511 R tRNA-Thr complement(3640439..3640511) Cronobacter sakazakii ATCC BAA-894 5551854 ESA_03701 tRNA ESA_03701 NC_009778.1 3640521 3640592 R tRNA-Gly complement(3640521..3640592) Cronobacter sakazakii ATCC BAA-894 5549906 ESA_03702 tRNA ESA_03702 NC_009778.1 3640704 3640785 R tRNA-Tyr complement(3640704..3640785) Cronobacter sakazakii ATCC BAA-894 5550319 ESA_03703 tRNA ESA_03703 NC_009778.1 3640798 3640870 R tRNA-Thr complement(3640798..3640870) Cronobacter sakazakii ATCC BAA-894 5550112 ESA_03708 tRNA ESA_03708 NC_009778.1 3647894 3647966 R tRNA-Glu complement(3647894..3647966) Cronobacter sakazakii ATCC BAA-894 5550122 ESA_03760 tRNA ESA_03760 NC_009778.1 3705297 3705370 R tRNA-Pro complement(3705297..3705370) Cronobacter sakazakii ATCC BAA-894 5548320 ESA_03761 tRNA ESA_03761 NC_009778.1 3705410 3705492 R tRNA-Leu complement(3705410..3705492) Cronobacter sakazakii ATCC BAA-894 5548214 ESA_03762 tRNA ESA_03762 NC_009778.1 3705518 3705590 R tRNA-His complement(3705518..3705590) Cronobacter sakazakii ATCC BAA-894 5548273 ESA_03763 tRNA ESA_03763 NC_009778.1 3705648 3705721 R tRNA-Arg complement(3705648..3705721) Cronobacter sakazakii ATCC BAA-894 5548367 ESA_03792 tRNA ESA_03792 NC_009778.1 3738718 3738790 R tRNA-Trp complement(3738718..3738790) Cronobacter sakazakii ATCC BAA-894 5548231 ESA_03793 tRNA ESA_03793 NC_009778.1 3738802 3738875 R tRNA-Asp complement(3738802..3738875) Cronobacter sakazakii ATCC BAA-894 5552292 ESA_03796 tRNA ESA_03796 NC_009778.1 3742210 3742282 R tRNA-Ala complement(3742210..3742282) Cronobacter sakazakii ATCC BAA-894 5548380 ESA_03797 tRNA ESA_03797 NC_009778.1 3742319 3742392 R tRNA-Ile complement(3742319..3742392) Cronobacter sakazakii ATCC BAA-894 5548102 ESA_04031 tRNA ESA_04031 NC_009778.1 3978367 3978439 D tRNA-Glu 3978367..3978439 Cronobacter sakazakii ATCC BAA-894 5550924 ESA_04411 tRNA ESA_04411 NC_009778.1 4104657 4104751 R tRNA-Sec complement(4104657..4104751) Cronobacter sakazakii ATCC BAA-894 9679596 ESA_04189 tRNA ESA_04189 NC_009778.1 4145660 4145733 D tRNA-Pro 4145660..4145733 Cronobacter sakazakii ATCC BAA-894 5550519 ESA_00047 rRNA ESA_00047 NC_009778.1 24905 26446 D 16S ribosomal RNA 24905..26446 Cronobacter sakazakii ATCC BAA-894 5550802 ESA_r01 rRNA ESA_r01 NC_009778.1 26947 29848 D 23S ribosomal RNA 26947..29848 Cronobacter sakazakii ATCC BAA-894 5696482 ESA_00051 rRNA ESA_00051 NC_009778.1 29939 30057 D 5S ribosomal RNA 29939..30057 Cronobacter sakazakii ATCC BAA-894 5549150 ESA_00663 rRNA ESA_00663 NC_009778.1 629768 631308 D 16S ribosomal RNA 629768..631308 Cronobacter sakazakii ATCC BAA-894 5551341 ESA_r02 rRNA ESA_r02 NC_009778.1 631732 634634 D 23S ribosomal RNA 631732..634634 Cronobacter sakazakii ATCC BAA-894 5696483 ESA_00668 rRNA ESA_00668 NC_009778.1 634727 634845 D 5S ribosomal RNA 634727..634845 Cronobacter sakazakii ATCC BAA-894 5551304 ESA_03134 rRNA ESA_03134 NC_009778.1 3049069 3049189 R 5S ribosomal RNA complement(3049069..3049189) Cronobacter sakazakii ATCC BAA-894 5549850 ESA_r03 rRNA ESA_r03 NC_009778.1 3049280 3052182 R 23S ribosomal RNA complement(3049280..3052182) Cronobacter sakazakii ATCC BAA-894 5696484 ESA_03137 rRNA ESA_03137 NC_009778.1 3052539 3054079 R 16S ribosomal RNA complement(3052539..3054079) Cronobacter sakazakii ATCC BAA-894 5550259 ESA_03663 rRNA ESA_03663 NC_009778.1 3604117 3604235 R 5S ribosomal RNA complement(3604117..3604235) Cronobacter sakazakii ATCC BAA-894 5550442 ESA_03665 rRNA ESA_03665 NC_009778.1 3604360 3604480 R 5S ribosomal RNA complement(3604360..3604480) Cronobacter sakazakii ATCC BAA-894 5550415 ESA_r04 rRNA ESA_r04 NC_009778.1 3604571 3607473 R 23S ribosomal RNA complement(3604571..3607473) Cronobacter sakazakii ATCC BAA-894 5696485 ESA_03669 rRNA ESA_03669 NC_009778.1 3607830 3609370 R 16S ribosomal RNA complement(3607830..3609370) Cronobacter sakazakii ATCC BAA-894 5550088 ESA_03706 rRNA ESA_03706 NC_009778.1 3644573 3644697 R 5S ribosomal RNA complement(3644573..3644697) Cronobacter sakazakii ATCC BAA-894 5550132 ESA_r05 rRNA ESA_r05 NC_009778.1 3644788 3647689 R 23S ribosomal RNA complement(3644788..3647689) Cronobacter sakazakii ATCC BAA-894 5696486 ESA_03709 rRNA ESA_03709 NC_009778.1 3648046 3649586 R 16S ribosomal RNA complement(3648046..3649586) Cronobacter sakazakii ATCC BAA-894 5550282 ESA_03794 rRNA ESA_03794 NC_009778.1 3738928 3739048 R 5S ribosomal RNA complement(3738928..3739048) Cronobacter sakazakii ATCC BAA-894 5550445 ESA_r06 rRNA ESA_r06 NC_009778.1 3739137 3742038 R 23S ribosomal RNA complement(3739137..3742038) Cronobacter sakazakii ATCC BAA-894 5696487 ESA_03798 rRNA ESA_03798 NC_009778.1 3742462 3744002 R 16S ribosomal RNA complement(3742462..3744002) Cronobacter sakazakii ATCC BAA-894 5548374 ESA_04030 rRNA ESA_04030 NC_009778.1 3976747 3978287 D 16S ribosomal RNA 3976747..3978287 Cronobacter sakazakii ATCC BAA-894 5550970 ESA_04408 rRNA ESA_04408 NC_009778.1 3978644 3981547 D 23S ribosomal RNA 3978644..3981547 Cronobacter sakazakii ATCC BAA-894 5550974 ESA_04032 rRNA ESA_04032 NC_009778.1 3981628 3981756 D 5S ribosomal RNA 3981628..3981756 Cronobacter sakazakii ATCC BAA-894 5552043