-- dump date 20140619_043505 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001919466.1 188589439 6319369 127..1497 1 NC_010723.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1497 dnaA 6319369 dnaA Clostridium botulinum E3 str. Alaska E43 chromosomal replication initiation protein YP_001919466.1 127 D 508767 CDS YP_001919467.1 188587627 6318307 1758..2858 1 NC_010723.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2858 dnaN 6318307 dnaN Clostridium botulinum E3 str. Alaska E43 DNA polymerase III subunit beta YP_001919467.1 1758 D 508767 CDS YP_001919468.1 188588344 6319360 2897..3103 1 NC_010723.1 identified by match to protein family HMM PF01479; match to protein family HMM TIGR02988; S4 domain-containing protein YaaA 3103 yaaA 6319360 yaaA Clostridium botulinum E3 str. Alaska E43 S4 domain-containing protein YaaA YP_001919468.1 2897 D 508767 CDS YP_001919469.1 188590699 6320122 3175..4260 1 NC_010723.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4260 recF 6320122 recF Clostridium botulinum E3 str. Alaska E43 recombination protein F YP_001919469.1 3175 D 508767 CDS YP_001919470.1 188589365 6318402 4275..4535 1 NC_010723.1 hypothetical protein 4535 6318402 CLH_0005 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919470.1 4275 D 508767 CDS YP_001919471.1 188588443 6319263 4571..6478 1 NC_010723.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 6478 gyrB 6319263 gyrB Clostridium botulinum E3 str. Alaska E43 DNA gyrase subunit B YP_001919471.1 4571 D 508767 CDS YP_001919472.1 188587904 6319741 6501..9050 1 NC_010723.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 9050 gyrA 6319741 gyrA Clostridium botulinum E3 str. Alaska E43 DNA gyrase subunit A YP_001919472.1 6501 D 508767 CDS YP_001919473.1 188588820 6318330 14633..15136 1 NC_010723.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; putative HD domain 15136 6318330 CLH_0014 Clostridium botulinum E3 str. Alaska E43 putative HD domain YP_001919473.1 14633 D 508767 CDS YP_001919474.1 188589343 6318174 15175..15687 1 NC_010723.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279; 3H domain-containing protein 15687 6318174 CLH_0015 Clostridium botulinum E3 str. Alaska E43 3H domain-containing protein YP_001919474.1 15175 D 508767 CDS YP_001919475.1 188588637 6317249 15700..17091 1 NC_010723.1 identified by match to protein family HMM PF01266; match to protein family HMM PF04324; FAD-dependent oxidoreductase 17091 6317249 CLH_0016 Clostridium botulinum E3 str. Alaska E43 FAD-dependent oxidoreductase YP_001919475.1 15700 D 508767 CDS YP_001919476.1 188587965 6320077 17110..17346 1 NC_010723.1 identified by match to protein family HMM PF07892; hypothetical protein 17346 6320077 CLH_0017 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919476.1 17110 D 508767 CDS YP_001919477.1 188588464 6317328 17662..18939 1 NC_010723.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 18939 serS 6317328 serS Clostridium botulinum E3 str. Alaska E43 seryl-tRNA synthetase YP_001919477.1 17662 D 508767 CDS YP_001919478.1 188588138 6320242 20253..20762 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 20762 6320242 CLH_0023 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001919478.1 20253 D 508767 CDS YP_001919479.1 188588814 6318574 20801..24259 1 NC_010723.1 identified by match to protein family HMM TIGR02773; ATP-dependent nuclease subunit B 24259 addB 6318574 addB Clostridium botulinum E3 str. Alaska E43 ATP-dependent nuclease subunit B YP_001919479.1 20801 D 508767 CDS YP_001919480.1 188589987 6320299 24285..28019 1 NC_010723.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785; recombination helicase AddA 28019 addA 6320299 addA Clostridium botulinum E3 str. Alaska E43 recombination helicase AddA YP_001919480.1 24285 D 508767 CDS YP_001919481.1 188590689 6319891 complement(28301..29452) 1 NC_010723.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 29452 6319891 CLH_0026 Clostridium botulinum E3 str. Alaska E43 ErfK/YbiS/YcfS/YnhG family protein YP_001919481.1 28301 R 508767 CDS YP_001919482.1 188588427 6317871 29608..30417 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 30417 6317871 CLH_0027 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919482.1 29608 D 508767 CDS YP_001919483.1 188589244 6318903 complement(30475..31644) 1 NC_010723.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 31644 6318903 CLH_0028 Clostridium botulinum E3 str. Alaska E43 sodium:dicarboxylate symporter family protein YP_001919483.1 30475 R 508767 CDS YP_001919484.1 188590164 6317504 31981..32877 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensory box histidine kinase 32877 6317504 CLH_0029 Clostridium botulinum E3 str. Alaska E43 sensory box histidine kinase YP_001919484.1 31981 D 508767 CDS YP_001919485.1 188587836 6320243 33324..34463 1 NC_010723.1 hypothetical protein 34463 6320243 CLH_0031 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919485.1 33324 D 508767 CDS YP_001919486.1 188587735 6317555 complement(34609..35499) 1 NC_010723.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 35499 psd 6317555 psd Clostridium botulinum E3 str. Alaska E43 phosphatidylserine decarboxylase YP_001919486.1 34609 R 508767 CDS YP_001919487.1 188590357 6319470 35661..36236 1 NC_010723.1 identified by match to protein family HMM PF00440; transcriptional regulator, TetR family 36236 6319470 CLH_0033 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, TetR family YP_001919487.1 35661 D 508767 CDS YP_001919488.1 188588322 6318593 36549..38279 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512; hydrogenase-1 38279 6318593 CLH_0034 Clostridium botulinum E3 str. Alaska E43 hydrogenase-1 YP_001919488.1 36549 D 508767 CDS YP_001919489.1 188589019 6319965 38556..39344 1 NC_010723.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR01484; HAD-superfamily hydrolase 39344 6319965 CLH_0035 Clostridium botulinum E3 str. Alaska E43 HAD-superfamily hydrolase YP_001919489.1 38556 D 508767 CDS YP_001919490.1 188588712 6319180 complement(39492..41087) 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 41087 6319180 CLH_0036 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001919490.1 39492 R 508767 CDS YP_001919491.1 188589253 6317756 41578..42891 1 NC_010723.1 identified by match to protein family HMM PF00209; sodium:neurotransmitter symporter family protein 42891 6317756 CLH_0037 Clostridium botulinum E3 str. Alaska E43 sodium:neurotransmitter symporter family protein YP_001919491.1 41578 D 508767 CDS YP_001919492.1 188588053 6317309 43066..43194 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 43194 6317309 CLH_0038 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919492.1 43066 D 508767 CDS YP_001919493.1 188587796 6319077 43383..43559 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 43559 6319077 CLH_0039 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919493.1 43383 D 508767 CDS YP_001919494.1 188589054 6317801 complement(43571..44218) 1 NC_010723.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin-3 44218 6317801 CLH_0040 Clostridium botulinum E3 str. Alaska E43 hemolysin-3 YP_001919494.1 43571 R 508767 CDS YP_001919495.1 188588299 6319571 44439..45020 1 NC_010723.1 identified by match to protein family HMM PF08876; hypothetical protein 45020 6319571 CLH_0041 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919495.1 44439 D 508767 CDS YP_001919496.1 188587858 6319905 45021..46721 1 NC_010723.1 isopentenyl-diphosphate delta-isomerase 46721 6319905 CLH_0042 Clostridium botulinum E3 str. Alaska E43 isopentenyl-diphosphate delta-isomerase YP_001919496.1 45021 D 508767 CDS YP_001919497.1 188589120 6317419 47187..47972 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 47972 6317419 CLH_0043 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919497.1 47187 D 508767 CDS YP_001919498.1 188590111 6319739 complement(48380..49735) 1 NC_010723.1 identified by match to protein family HMM PF07670; membrane protein 49735 6319739 CLH_0044 Clostridium botulinum E3 str. Alaska E43 membrane protein YP_001919498.1 48380 R 508767 CDS YP_001919499.1 188587949 6320081 49985..51679 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis sensory transducer 51679 6320081 CLH_0045 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis sensory transducer YP_001919499.1 49985 D 508767 CDS YP_001919500.1 188589662 6317339 51852..52661 1 NC_010723.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 52661 proB 6317339 proB Clostridium botulinum E3 str. Alaska E43 gamma-glutamyl kinase YP_001919500.1 51852 D 508767 CDS YP_001919501.1 188590471 6320118 52678..53922 1 NC_010723.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 53922 proA 6320118 proA Clostridium botulinum E3 str. Alaska E43 gamma-glutamyl phosphate reductase YP_001919501.1 52678 D 508767 CDS YP_001919502.1 188590642 6317446 54052..54492 1 NC_010723.1 identified by match to protein family HMM PF00583; acetyltransferase 54492 6317446 CLH_0048 Clostridium botulinum E3 str. Alaska E43 acetyltransferase YP_001919502.1 54052 D 508767 CDS YP_001919503.1 188588024 6320311 54838..55344 1 NC_010723.1 identified by match to protein family HMM PF03703; membrane flanked domain family 55344 6320311 CLH_0049 Clostridium botulinum E3 str. Alaska E43 membrane flanked domain family YP_001919503.1 54838 D 508767 CDS YP_001919504.1 188588362 6319287 55322..56749 1 NC_010723.1 identified by match to protein family HMM PF03703; putative membrane flanked domain family 56749 6319287 CLH_0050 Clostridium botulinum E3 str. Alaska E43 putative membrane flanked domain family YP_001919504.1 55322 D 508767 CDS YP_001919505.1 188589300 6319624 56976..57746 1 NC_010723.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 57746 6319624 CLH_0051 Clostridium botulinum E3 str. Alaska E43 short chain dehydrogenase YP_001919505.1 56976 D 508767 CDS YP_001919506.1 188588815 6319925 58130..58942 1 NC_010723.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 58942 6319925 CLH_0052 Clostridium botulinum E3 str. Alaska E43 HAD superfamily hydrolase YP_001919506.1 58130 D 508767 CDS YP_001919507.1 188590375 6320291 59038..60495 1 NC_010723.1 identified by match to protein family HMM PF00015; putative methyl-accepting chemotaxis protein 60495 6320291 CLH_0053 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis protein YP_001919507.1 59038 D 508767 CDS YP_001919508.1 188587992 6320486 60868..61917 1 NC_010723.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 61917 carA 6320486 carA Clostridium botulinum E3 str. Alaska E43 carbamoyl phosphate synthase small subunit YP_001919508.1 60868 D 508767 CDS YP_001919509.1 188588895 6317529 61932..65141 1 NC_010723.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 65141 carB 6317529 carB Clostridium botulinum E3 str. Alaska E43 carbamoyl phosphate synthase large subunit YP_001919509.1 61932 D 508767 CDS YP_001919510.1 188588943 6319365 complement(65185..66294) 1 NC_010723.1 identified by match to protein family HMM PF01966; HD-GYP hydrolase domain containing protein 66294 6319365 CLH_0056 Clostridium botulinum E3 str. Alaska E43 HD-GYP hydrolase domain containing protein YP_001919510.1 65185 R 508767 CDS YP_001919511.1 188590299 6318023 complement(66577..68469) 1 NC_010723.1 identified by match to protein family HMM PF00120; glutamine synthetase 68469 6318023 CLH_0057 Clostridium botulinum E3 str. Alaska E43 glutamine synthetase YP_001919511.1 66577 R 508767 CDS YP_001919512.1 188587547 6317953 68787..69563 1 NC_010723.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 69563 murI 6317953 murI Clostridium botulinum E3 str. Alaska E43 glutamate racemase YP_001919512.1 68787 D 508767 CDS YP_001919513.1 188588453 6319080 69704..70228 1 NC_010723.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase 70228 6319080 CLH_0059 Clostridium botulinum E3 str. Alaska E43 peptidyl-prolyl cis-trans isomerase YP_001919513.1 69704 D 508767 CDS YP_001919514.1 188589749 6319666 70407..70775 1 NC_010723.1 hypothetical protein 70775 6319666 CLH_0060 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919514.1 70407 D 508767 CDS YP_001919515.1 188590670 6319488 70777..71445 1 NC_010723.1 identified by match to protein family HMM PF01381; DNA-binding protein 71445 6319488 CLH_0061 Clostridium botulinum E3 str. Alaska E43 DNA-binding protein YP_001919515.1 70777 D 508767 CDS YP_001919516.1 188588216 6317902 71609..75205 1 NC_010723.1 identified by match to protein family HMM PF00082; subtilisin like protease 75205 6317902 CLH_0062 Clostridium botulinum E3 str. Alaska E43 subtilisin like protease YP_001919516.1 71609 D 508767 CDS YP_001919517.1 188588622 6319669 75295..76626 1 NC_010723.1 identified by match to protein family HMM PF01471; spore cortex-lytic protein 76626 6319669 CLH_0063 Clostridium botulinum E3 str. Alaska E43 spore cortex-lytic protein YP_001919517.1 75295 D 508767 CDS YP_001919518.1 188587854 6318538 complement(76667..77572) 1 NC_010723.1 identified by match to protein family HMM PF04055; radical SAM domain protein 77572 6318538 CLH_0064 Clostridium botulinum E3 str. Alaska E43 radical SAM domain protein YP_001919518.1 76667 R 508767 CDS YP_001919519.1 188588722 6319067 complement(77724..78782) 1 NC_010723.1 transporter 78782 6319067 CLH_0065 Clostridium botulinum E3 str. Alaska E43 transporter YP_001919519.1 77724 R 508767 CDS YP_001919520.1 188589590 6320565 78917..79987 1 NC_010723.1 putative lipoprotein 79987 6320565 CLH_0066 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001919520.1 78917 D 508767 CDS YP_001919521.1 188590566 6319209 80080..81018 1 NC_010723.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212; radical SAM protein, family 81018 6319209 CLH_0067 Clostridium botulinum E3 str. Alaska E43 radical SAM protein, family YP_001919521.1 80080 D 508767 CDS YP_001919522.1 188588175 6318791 81019..81735 1 NC_010723.1 catalyzes the formation of (2R)-3-sulfolactate from (2R)-2-phospho-3-sulfolactate; 2-phosphosulfolactate phosphatase 81735 6318791 CLH_0068 Clostridium botulinum E3 str. Alaska E43 2-phosphosulfolactate phosphatase YP_001919522.1 81019 D 508767 CDS YP_001919523.1 188589114 6319454 complement(81760..82950) 1 NC_010723.1 identified by match to protein family HMM PF01170; match to protein family HMM PF02475; PUA domain containing protein 82950 6319454 CLH_0069 Clostridium botulinum E3 str. Alaska E43 PUA domain containing protein YP_001919523.1 81760 R 508767 CDS YP_001919524.1 188590159 6320553 complement(83498..83707) 1 NC_010723.1 identified by match to protein family HMM PF04324; hypothetical protein 83707 6320553 CLH_0070 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919524.1 83498 R 508767 CDS YP_001919525.1 188587672 6317285 84214..84897 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 84897 6317285 CLH_0071 Clostridium botulinum E3 str. Alaska E43 DNA-binding response regulator YP_001919525.1 84214 D 508767 CDS YP_001919526.1 188590055 6318106 84903..86189 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 86189 6318106 CLH_0072 Clostridium botulinum E3 str. Alaska E43 sensor histidine kinase YP_001919526.1 84903 D 508767 CDS YP_001919527.1 188590233 6320557 86484..87170 1 NC_010723.1 identified by match to protein family HMM PF09359; VTC domain superfamily 87170 6320557 CLH_0073 Clostridium botulinum E3 str. Alaska E43 VTC domain superfamily YP_001919527.1 86484 D 508767 CDS YP_001919528.1 188589557 6319111 87205..87894 1 NC_010723.1 twin-arginine translocating C- subunit 87894 6319111 CLH_0074 Clostridium botulinum E3 str. Alaska E43 twin-arginine translocating C- subunit YP_001919528.1 87205 D 508767 CDS YP_001919529.1 188589185 6318191 88011..90119 1 NC_010723.1 identified by match to protein family HMM PF08757; CotH protein 90119 6318191 CLH_0075 Clostridium botulinum E3 str. Alaska E43 CotH protein YP_001919529.1 88011 D 508767 CDS YP_001919530.1 188588720 6319056 90401..92380 1 NC_010723.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872; 2', 3'-cuclic nucleotide 2'-phosphodiesterase 92380 6319056 CLH_0076 Clostridium botulinum E3 str. Alaska E43 2', 3'-cuclic nucleotide 2'-phosphodiesterase YP_001919530.1 90401 D 508767 CDS YP_001919531.1 188587779 6317694 92583..92705 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 92705 6317694 CLH_0077 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919531.1 92583 D 508767 CDS YP_001919532.1 188589689 6318276 93183..96293 1 NC_010723.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 96293 ileS 6318276 ileS Clostridium botulinum E3 str. Alaska E43 isoleucyl-tRNA synthetase YP_001919532.1 93183 D 508767 CDS YP_001919533.1 188588416 6320072 96400..97398 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; catabolite control protein A 97398 6320072 CLH_0079 Clostridium botulinum E3 str. Alaska E43 catabolite control protein A YP_001919533.1 96400 D 508767 CDS YP_001919534.1 188587703 6318831 97693..98118 1 NC_010723.1 putative viral A-type inclusion protein 98118 6318831 CLH_0080 Clostridium botulinum E3 str. Alaska E43 putative viral A-type inclusion protein YP_001919534.1 97693 D 508767 CDS YP_001919535.1 188589856 6318453 98244..99623 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 99623 6318453 CLH_0081 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001919535.1 98244 D 508767 CDS YP_001919536.1 188588812 6320125 complement(99677..99862) 1 NC_010723.1 hypothetical protein 99862 6320125 CLH_0082 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919536.1 99677 R 508767 CDS YP_001919537.1 188590546 6320297 99972..100547 1 NC_010723.1 identified by match to protein family HMM PF07670; hypothetical protein 100547 6320297 CLH_0083 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919537.1 99972 D 508767 CDS YP_001919538.1 188588219 6317963 100563..101090 1 NC_010723.1 identified by match to protein family HMM PF07670; hypothetical protein 101090 6317963 CLH_0084 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919538.1 100563 D 508767 CDS YP_001919539.1 188588730 6319678 101195..101527 1 NC_010723.1 hypothetical protein 101527 6319678 CLH_0085 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919539.1 101195 D 508767 CDS YP_001919540.1 188589718 6320047 101701..103311 1 NC_010723.1 identified by match to protein family HMM PF03109; ABC1 family protein kinase 103311 6320047 CLH_0086 Clostridium botulinum E3 str. Alaska E43 ABC1 family protein kinase YP_001919540.1 101701 D 508767 CDS YP_001919541.1 188589417 6317895 103872..105590 1 NC_010723.1 identified by match to protein family HMM PF03553; Na+/H+ antiporter family 105590 6317895 CLH_0087 Clostridium botulinum E3 str. Alaska E43 Na+/H+ antiporter family YP_001919541.1 103872 D 508767 CDS YP_001919542.1 188590364 6320434 106001..107776 1 NC_010723.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro aminopeptidase 1 107776 6320434 CLH_0088 Clostridium botulinum E3 str. Alaska E43 Xaa-Pro aminopeptidase 1 YP_001919542.1 106001 D 508767 CDS YP_001919543.1 188587574 6320528 complement(107848..108345) 1 NC_010723.1 hypothetical protein 108345 6320528 CLH_0089 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919543.1 107848 R 508767 CDS YP_001919544.1 188588469 6317914 108445..109851 1 NC_010723.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; AAA ATPase 109851 6317914 CLH_0090 Clostridium botulinum E3 str. Alaska E43 AAA ATPase YP_001919544.1 108445 D 508767 CDS YP_001919545.1 188589558 6319921 109978..110901 1 NC_010723.1 hydrolase, alpha/beta fold family 110901 6319921 CLH_0091 Clostridium botulinum E3 str. Alaska E43 hydrolase, alpha/beta fold family YP_001919545.1 109978 D 508767 CDS YP_001919546.1 188590525 6318192 111358..112062 1 NC_010723.1 identified by match to protein family HMM PF00230; glycerol uptake facilitator protein 112062 6318192 CLH_0092 Clostridium botulinum E3 str. Alaska E43 glycerol uptake facilitator protein YP_001919546.1 111358 D 508767 CDS YP_001919547.1 188589551 6317927 112175..113170 1 NC_010723.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 113170 dhaK 6317927 dhaK Clostridium botulinum E3 str. Alaska E43 dihydroxyacetone kinase subunit DhaK YP_001919547.1 112175 D 508767 CDS YP_001919548.1 188590334 6318808 113198..113836 1 NC_010723.1 identified by match to protein family HMM PF02734; match to protein family HMM TIGR02365; dihydroxyacetone kinase subunit DhaL 113836 6318808 CLH_0094 Clostridium botulinum E3 str. Alaska E43 dihydroxyacetone kinase subunit DhaL YP_001919548.1 113198 D 508767 CDS YP_001919549.1 188587620 6318601 113839..114228 1 NC_010723.1 identified by match to protein family HMM PF03610; match to protein family HMM TIGR02364; PTS system mannnose-specific transporter subunit IIA 114228 6318601 CLH_0095 Clostridium botulinum E3 str. Alaska E43 PTS system mannnose-specific transporter subunit IIA YP_001919549.1 113839 D 508767 CDS YP_001919550.1 188588457 6319414 114812..116749 1 NC_010723.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 116749 metG 6319414 metG Clostridium botulinum E3 str. Alaska E43 methionyl-tRNA synthetase YP_001919550.1 114812 D 508767 CDS YP_001919551.1 188589859 6318710 117053..117850 1 NC_010723.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; putative deoxyribonuclease 117850 6318710 CLH_0097 Clostridium botulinum E3 str. Alaska E43 putative deoxyribonuclease YP_001919551.1 117053 D 508767 CDS YP_001919552.1 188590715 6317263 118133..119179 1 NC_010723.1 identified by match to protein family HMM PF03990; match to protein family HMM PF06725; match to protein family HMM PF07501; hypothetical protein 119179 6317263 CLH_0098 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919552.1 118133 D 508767 CDS YP_001919553.1 188589065 6319297 119347..119901 1 NC_010723.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; putative primase-like protein 119901 6319297 CLH_0099 Clostridium botulinum E3 str. Alaska E43 putative primase-like protein YP_001919553.1 119347 D 508767 CDS YP_001919554.1 188588306 6319335 119905..120756 1 NC_010723.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 120756 ksgA 6319335 ksgA Clostridium botulinum E3 str. Alaska E43 dimethyladenosine transferase YP_001919554.1 119905 D 508767 CDS YP_001919555.1 188590309 6320001 120949..122385 1 NC_010723.1 hypothetical protein 122385 6320001 CLH_0101 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919555.1 120949 D 508767 CDS YP_001919556.1 188589845 6318700 122396..122965 1 NC_010723.1 hypothetical protein 122965 6318700 CLH_0102 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919556.1 122396 D 508767 CDS YP_001919557.1 188588100 6319236 123063..123821 1 NC_010723.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 123821 lgt 6319236 lgt Clostridium botulinum E3 str. Alaska E43 prolipoprotein diacylglyceryl transferase YP_001919557.1 123063 D 508767 CDS YP_001919558.1 188588373 6319253 123822..124655 1 NC_010723.1 putative lipoprotein 124655 6319253 CLH_0104 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001919558.1 123822 D 508767 CDS YP_001919559.1 188589582 6320004 124671..125513 1 NC_010723.1 Mrp protein 125513 6320004 CLH_0105 Clostridium botulinum E3 str. Alaska E43 Mrp protein YP_001919559.1 124671 D 508767 CDS YP_001919560.1 188590707 6319405 125580..125768 1 NC_010723.1 hypothetical protein 125768 6319405 CLH_0106 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919560.1 125580 D 508767 CDS YP_001919561.1 188588380 6318407 complement(125928..126605) 1 NC_010723.1 identified by match to protein family HMM PF09515; match to protein family HMM TIGR02357; proton-coupled thiamine transporter YuaJ 126605 6318407 CLH_0107 Clostridium botulinum E3 str. Alaska E43 proton-coupled thiamine transporter YuaJ YP_001919561.1 125928 R 508767 CDS YP_001919562.1 188588824 6319761 complement(126861..127067) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 127067 6319761 CLH_0108 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919562.1 126861 R 508767 CDS YP_001919563.1 188589983 6318715 complement(127240..127692) 1 NC_010723.1 identified by match to protein family HMM PF03551; transcriptional regulator, PadR family 127692 6318715 CLH_0109 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, PadR family YP_001919563.1 127240 R 508767 CDS YP_001919564.1 188590171 6318185 complement(127694..128542) 1 NC_010723.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 128542 6318185 CLH_0110 Clostridium botulinum E3 str. Alaska E43 DegV family protein YP_001919564.1 127694 R 508767 CDS YP_001919565.1 188589097 6318339 128841..130946 1 NC_010723.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 130946 nrdD 6318339 nrdD Clostridium botulinum E3 str. Alaska E43 anaerobic ribonucleoside triphosphate reductase YP_001919565.1 128841 D 508767 CDS YP_001919566.1 188588746 6319192 131374..132528 1 NC_010723.1 in Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis; trans-homoaconitate synthase 132528 aksA 6319192 aksA Clostridium botulinum E3 str. Alaska E43 trans-homoaconitate synthase YP_001919566.1 131374 D 508767 CDS YP_001919567.1 188587768 6317449 132706..134628 1 NC_010723.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 134628 6317449 CLH_0113 Clostridium botulinum E3 str. Alaska E43 aconitate hydratase YP_001919567.1 132706 D 508767 CDS YP_001919568.1 188588270 6319387 134848..137103 1 NC_010723.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254; putative signaling protein 137103 6319387 CLH_0114 Clostridium botulinum E3 str. Alaska E43 putative signaling protein YP_001919568.1 134848 D 508767 CDS YP_001919569.1 188588785 6319826 137327..137836 1 NC_010723.1 identified by match to protein family HMM TIGR02491; anaerobic ribonucleoside-triphosphate reductase activating protein 137836 nrdG 6319826 nrdG Clostridium botulinum E3 str. Alaska E43 anaerobic ribonucleoside-triphosphate reductase activating protein YP_001919569.1 137327 D 508767 CDS YP_001919570.1 188589217 6318302 137913..138521 1 NC_010723.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 138521 6318302 CLH_0116 Clostridium botulinum E3 str. Alaska E43 3-methyladenine DNA glycosylase YP_001919570.1 137913 D 508767 CDS YP_001919571.1 188590687 6317510 138994..139998 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; catabolite control protein A 139998 6317510 CLH_0117 Clostridium botulinum E3 str. Alaska E43 catabolite control protein A YP_001919571.1 138994 D 508767 CDS YP_001919572.1 188587788 6317869 140078..141739 1 NC_010723.1 identified by match to protein family HMM PF00128; oligo-1,6-glucosidase 141739 6317869 CLH_0118 Clostridium botulinum E3 str. Alaska E43 oligo-1,6-glucosidase YP_001919572.1 140078 D 508767 CDS YP_001919573.1 188588409 6318213 141831..143111 1 NC_010723.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 143111 6318213 CLH_0119 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter substrate-binding protein YP_001919573.1 141831 D 508767 CDS YP_001919574.1 188589241 6320007 143136..143999 1 NC_010723.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 143999 6320007 CLH_0120 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter permease YP_001919574.1 143136 D 508767 CDS YP_001919575.1 188590373 6318251 143999..144868 1 NC_010723.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 144868 6318251 CLH_0121 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter permease YP_001919575.1 143999 D 508767 CDS YP_001919576.1 188587841 6320506 complement(145006..145170) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 145170 6320506 CLH_0122 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919576.1 145006 R 508767 CDS YP_001919577.1 188588914 6318692 145335..146498 1 NC_010723.1 identified by match to protein family HMM PF09587; encapsulation protein CapA 146498 6318692 CLH_0123 Clostridium botulinum E3 str. Alaska E43 encapsulation protein CapA YP_001919577.1 145335 D 508767 CDS YP_001919578.1 188589434 6317898 147624..148220 1 NC_010723.1 hypothetical protein 148220 6317898 CLH_0124 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919578.1 147624 D 508767 CDS YP_001919579.1 188590325 6318344 148239..149084 1 NC_010723.1 identified by match to protein family HMM PF05065; phage capsid family 149084 6318344 CLH_0125 Clostridium botulinum E3 str. Alaska E43 phage capsid family YP_001919579.1 148239 D 508767 CDS YP_001919580.1 188587730 6319037 149149..149556 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 149556 6319037 CLH_0126 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919580.1 149149 D 508767 CDS YP_001919581.1 188588249 6318669 149558..149803 1 NC_010723.1 hypothetical protein 149803 6318669 CLH_0127 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919581.1 149558 D 508767 CDS YP_001919582.1 188588570 6319536 complement(149835..150353) 1 NC_010723.1 identified by match to protein family HMM PF01381; dna-binding protein 150353 6319536 CLH_0128 Clostridium botulinum E3 str. Alaska E43 dna-binding protein YP_001919582.1 149835 R 508767 CDS YP_001919583.1 188589721 6320317 150549..150740 1 NC_010723.1 hypothetical protein 150740 6320317 CLH_0129 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919583.1 150549 D 508767 CDS YP_001919584.1 188588977 6318051 150758..152896 1 NC_010723.1 identified by match to protein family HMM PF09250; match to protein family HMM TIGR01613; putative primase 152896 6318051 CLH_0130 Clostridium botulinum E3 str. Alaska E43 putative primase YP_001919584.1 150758 D 508767 CDS YP_001919585.1 188589289 6319461 152920..153180 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 153180 6319461 CLH_0131 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919585.1 152920 D 508767 CDS YP_001919586.1 188590101 6320409 153390..153707 1 NC_010723.1 hypothetical protein 153707 6320409 CLH_0132 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919586.1 153390 D 508767 CDS YP_001919587.1 188590222 6317356 153822..154991 1 NC_010723.1 identified by match to protein family HMM PF00589; phage integrase 154991 6317356 CLH_0133 Clostridium botulinum E3 str. Alaska E43 phage integrase YP_001919587.1 153822 D 508767 CDS YP_001919588.1 188588043 6320454 complement(155357..156751) 1 NC_010723.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 156751 asnC 6320454 asnC Clostridium botulinum E3 str. Alaska E43 asparaginyl-tRNA synthetase YP_001919588.1 155357 R 508767 CDS YP_001919589.1 188589160 6318510 complement(157158..157856) 1 NC_010723.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; Ser/Thr protein phosphatase family protein 157856 6318510 CLH_0135 Clostridium botulinum E3 str. Alaska E43 Ser/Thr protein phosphatase family protein YP_001919589.1 157158 R 508767 CDS YP_001919590.1 188589883 6318561 158118..159194 1 NC_010723.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; metallopeptidase, family M24 159194 6318561 CLH_0136 Clostridium botulinum E3 str. Alaska E43 metallopeptidase, family M24 YP_001919590.1 158118 D 508767 CDS YP_001919591.1 188589349 6317907 complement(159299..160681) 1 NC_010723.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 160681 murC 6317907 murC Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylmuramate--L-alanine ligase YP_001919591.1 159299 R 508767 CDS YP_001919592.1 188590084 6318535 160972..161787 1 NC_010723.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743; pur operon repressor 161787 purR 6318535 purR Clostridium botulinum E3 str. Alaska E43 pur operon repressor YP_001919592.1 160972 D 508767 CDS YP_001919593.1 188587590 6317282 161908..162183 1 NC_010723.1 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus; regulatory protein SpoVG 162183 6317282 CLH_0139 Clostridium botulinum E3 str. Alaska E43 regulatory protein SpoVG YP_001919593.1 161908 D 508767 CDS YP_001919594.1 188590399 6318189 162371..163738 1 NC_010723.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 163738 glmU 6318189 glmU Clostridium botulinum E3 str. Alaska E43 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001919594.1 162371 D 508767 CDS YP_001919595.1 188587550 6318002 163784..164743 1 NC_010723.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251; ribose-phosphate diphosphokinase 164743 prs 6318002 prs Clostridium botulinum E3 str. Alaska E43 ribose-phosphate diphosphokinase YP_001919595.1 163784 D 508767 CDS YP_001919596.1 188588874 6318712 164858..165544 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two-component response regulator 165544 6318712 CLH_0142 Clostridium botulinum E3 str. Alaska E43 two-component response regulator YP_001919596.1 164858 D 508767 CDS YP_001919597.1 188588535 6318265 165625..166200 1 NC_010723.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 166200 pth 6318265 pth Clostridium botulinum E3 str. Alaska E43 peptidyl-tRNA hydrolase YP_001919597.1 165625 D 508767 CDS YP_001919598.1 188589474 6318486 166215..169718 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 169718 mfd 6318486 mfd Clostridium botulinum E3 str. Alaska E43 transcription-repair coupling factor YP_001919598.1 166215 D 508767 CDS YP_001919599.1 188590380 6317278 169854..170885 1 NC_010723.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; peptidyl-prolyl isomerase 170885 prsA 6317278 prsA Clostridium botulinum E3 str. Alaska E43 peptidyl-prolyl isomerase YP_001919599.1 169854 D 508767 CDS YP_001919600.1 188588336 6320361 171077..171628 1 NC_010723.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851; stage V sporulation protein T 171628 spoVT 6320361 spoVT Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein T YP_001919600.1 171077 D 508767 CDS YP_001919601.1 188587603 6318034 171730..173265 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023; stage V sporulation protein B 173265 6318034 CLH_0147 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein B YP_001919601.1 171730 D 508767 CDS YP_001919602.1 188589777 6319641 173280..174746 1 NC_010723.1 identified by match to protein family HMM PF00590; match to protein family HMM PF03819; match to protein family HMM TIGR00444; MazG family protein 174746 6319641 CLH_0148 Clostridium botulinum E3 str. Alaska E43 MazG family protein YP_001919602.1 173280 D 508767 CDS YP_001919603.1 188590511 6320420 174948..175226 1 NC_010723.1 identified by match to protein family HMM PF00216; DNA-binding protein HU 175226 hup 6320420 hup Clostridium botulinum E3 str. Alaska E43 DNA-binding protein HU YP_001919603.1 174948 D 508767 CDS YP_001919604.1 188589050 6318081 175278..175538 1 NC_010723.1 identified by match to protein family HMM PF01479; S4 domain-containing protein 175538 6318081 CLH_0150 Clostridium botulinum E3 str. Alaska E43 S4 domain-containing protein YP_001919604.1 175278 D 508767 CDS YP_001919605.1 188588049 6319943 175671..175964 1 NC_010723.1 identified by match to protein family HMM PF07873; match to protein family HMM TIGR02892; sporulation protein YabP 175964 yabP 6319943 yabP Clostridium botulinum E3 str. Alaska E43 sporulation protein YabP YP_001919605.1 175671 D 508767 CDS YP_001919606.1 188589259 6319008 176018..176374 1 NC_010723.1 identified by match to protein family HMM PF09578; match to protein family HMM TIGR02893; spore cortex biosynthesis protein YabQ 176374 yabQ 6319008 yabQ Clostridium botulinum E3 str. Alaska E43 spore cortex biosynthesis protein YabQ YP_001919606.1 176018 D 508767 CDS YP_001919607.1 188590184 6318768 176453..176746 1 NC_010723.1 identified by match to protein family HMM PF04977; cell division protein 176746 6318768 CLH_0153 Clostridium botulinum E3 str. Alaska E43 cell division protein YP_001919607.1 176453 D 508767 CDS YP_001919608.1 188588644 6318031 176802..177218 1 NC_010723.1 identified by match to protein family HMM PF00575; hypothetical protein 177218 6318031 CLH_0154 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919608.1 176802 D 508767 CDS YP_001919609.1 188587923 6319226 178680..181061 1 NC_010723.1 identified by match to protein family HMM PF07228; match to protein family HMM TIGR02865; stage II sporulation protein E 181061 spoIIE 6319226 spoIIE Clostridium botulinum E3 str. Alaska E43 stage II sporulation protein E YP_001919609.1 178680 D 508767 CDS YP_001919610.1 188588191 6318524 181200..182606 1 NC_010723.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthase 182606 6318524 CLH_0163 Clostridium botulinum E3 str. Alaska E43 tRNA(Ile)-lysidine synthase YP_001919610.1 181200 D 508767 CDS YP_001919611.1 188590712 6319135 182612..183151 1 NC_010723.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 183151 hpt 6319135 hpt Clostridium botulinum E3 str. Alaska E43 hypoxanthine phosphoribosyltransferase YP_001919611.1 182612 D 508767 CDS YP_001919612.1 188589992 6318787 183225..185030 1 NC_010723.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; Cell division protease FtsH 185030 6318787 CLH_0165 Clostridium botulinum E3 str. Alaska E43 Cell division protease FtsH YP_001919612.1 183225 D 508767 CDS YP_001919613.1 188588461 6318973 185252..186922 1 NC_010723.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 186922 fhs 6318973 fhs Clostridium botulinum E3 str. Alaska E43 formate--tetrahydrofolate ligase YP_001919613.1 185252 D 508767 CDS YP_001919614.1 188590305 6319549 187044..187817 1 NC_010723.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 187817 6319549 CLH_0167 Clostridium botulinum E3 str. Alaska E43 pantothenate kinase YP_001919614.1 187044 D 508767 CDS YP_001919615.1 188588843 6318515 187823..188788 1 NC_010723.1 identified by match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 188788 6318515 CLH_0168 Clostridium botulinum E3 str. Alaska E43 tRNA-dihydrouridine synthase B YP_001919615.1 187823 D 508767 CDS YP_001919616.1 188588098 6318648 188976..189680 1 NC_010723.1 hypothetical protein 189680 6318648 CLH_0169 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919616.1 188976 D 508767 CDS YP_001919617.1 188590469 6319251 189795..190277 1 NC_010723.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 190277 greA 6319251 greA Clostridium botulinum E3 str. Alaska E43 transcription elongation factor GreA YP_001919617.1 189795 D 508767 CDS YP_001919618.1 188587577 6317444 190322..191827 1 NC_010723.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 191827 lysS 6317444 lysS Clostridium botulinum E3 str. Alaska E43 lysyl-tRNA synthetase YP_001919618.1 190322 D 508767 CDS YP_001919619.1 188588486 6317690 complement(193163..193882) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 193882 6317690 CLH_0175 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919619.1 193163 R 508767 CDS YP_001919620.1 188590169 6320151 194016..195407 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 195407 6320151 CLH_0176 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919620.1 194016 D 508767 CDS YP_001919621.1 188587766 6318839 195440..196600 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 196600 6318839 CLH_0177 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919621.1 195440 D 508767 CDS YP_001919622.1 188588761 6319450 196622..197413 1 NC_010723.1 identified by match to protein family HMM PF05738; Cna B-type domain-containing protein 197413 6319450 CLH_0178 Clostridium botulinum E3 str. Alaska E43 Cna B-type domain-containing protein YP_001919622.1 196622 D 508767 CDS YP_001919623.1 188588855 6318981 197592..197735 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 197735 6318981 CLH_0179 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919623.1 197592 D 508767 CDS YP_001919624.1 188588755 6317758 197802..199193 1 NC_010723.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 199193 glyS 6317758 glyS Clostridium botulinum E3 str. Alaska E43 glycyl-tRNA synthetase YP_001919624.1 197802 D 508767 CDS YP_001919625.1 188587819 6317782 199381..200757 1 NC_010723.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 200757 murD 6317782 murD Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001919625.1 199381 D 508767 CDS YP_001919626.1 188589603 6318855 complement(200904..201908) 1 NC_010723.1 putative lipoprotein 201908 6318855 CLH_0182 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001919626.1 200904 R 508767 CDS YP_001919627.1 188589850 6319403 complement(207806..208753) 1 NC_010723.1 identified by match to protein family HMM PF01544; magnesium and cobalt transporter 208753 6319403 CLH_0191 Clostridium botulinum E3 str. Alaska E43 magnesium and cobalt transporter YP_001919627.1 207806 R 508767 CDS YP_001919628.1 188590774 6320394 209030..209506 1 NC_010723.1 hypothetical protein 209506 6320394 CLH_0192 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919628.1 209030 D 508767 CDS YP_001919629.1 188588039 6317856 complement(209567..210727) 1 NC_010723.1 amidohydrolase 210727 6317856 CLH_0193 Clostridium botulinum E3 str. Alaska E43 amidohydrolase YP_001919629.1 209567 R 508767 CDS YP_001919630.1 188590245 6319222 210785..210898 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 210898 6319222 CLH_0194 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919630.1 210785 D 508767 CDS YP_001919631.1 188590538 6317652 210888..211058 1 NC_010723.1 putative CsfB protein 211058 6317652 CLH_0195 Clostridium botulinum E3 str. Alaska E43 putative CsfB protein YP_001919631.1 210888 D 508767 CDS YP_001919632.1 188587973 6320179 211211..211888 1 NC_010723.1 identified by match to protein family HMM PF02223; thymidylate kinase 211888 6320179 CLH_0196 Clostridium botulinum E3 str. Alaska E43 thymidylate kinase YP_001919632.1 211211 D 508767 CDS YP_001919633.1 188589063 6317537 212003..212335 1 NC_010723.1 identified by match to protein family HMM PF06153; protein from nitrogen regulatory protein P-II 212335 6317537 CLH_0197 Clostridium botulinum E3 str. Alaska E43 protein from nitrogen regulatory protein P-II YP_001919633.1 212003 D 508767 CDS YP_001919634.1 188589337 6320232 212347..213279 1 NC_010723.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 213279 6320232 CLH_0198 Clostridium botulinum E3 str. Alaska E43 DNA polymerase III subunit delta' YP_001919634.1 212347 D 508767 CDS YP_001919635.1 188590028 6318836 213283..214191 1 NC_010723.1 identified by match to protein family HMM PF04468; PSP1 domain-containing protein 214191 6318836 CLH_0199 Clostridium botulinum E3 str. Alaska E43 PSP1 domain-containing protein YP_001919635.1 213283 D 508767 CDS YP_001919636.1 188590020 6318871 214336..214506 1 NC_010723.1 identified by match to protein family HMM PF00037; hypothetical protein 214506 6318871 CLH_0200 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919636.1 214336 D 508767 CDS YP_001919637.1 188590751 6319539 complement(214638..215276) 1 NC_010723.1 hypothetical protein 215276 6319539 CLH_0201 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919637.1 214638 R 508767 CDS YP_001919638.1 188589881 6320207 215468..215923 1 NC_010723.1 identified by match to protein family HMM PF05848; CtsR family transcriptional regulator 215923 6320207 CLH_0202 Clostridium botulinum E3 str. Alaska E43 CtsR family transcriptional regulator YP_001919638.1 215468 D 508767 CDS YP_001919639.1 188588966 6317905 215938..216513 1 NC_010723.1 identified by match to protein family HMM PF02151; McsA protein 216513 6317905 CLH_0203 Clostridium botulinum E3 str. Alaska E43 McsA protein YP_001919639.1 215938 D 508767 CDS YP_001919640.1 188587808 6319823 216497..217510 1 NC_010723.1 identified by match to protein family HMM PF00217; ATP:guanido phosphotransferase 217510 6319823 CLH_0204 Clostridium botulinum E3 str. Alaska E43 ATP:guanido phosphotransferase YP_001919640.1 216497 D 508767 CDS YP_001919641.1 188590460 6319500 217541..219985 1 NC_010723.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; negative regulator of genetic competence ClpC/mecB 219985 6319500 CLH_0205 Clostridium botulinum E3 str. Alaska E43 negative regulator of genetic competence ClpC/mecB YP_001919641.1 217541 D 508767 CDS YP_001919642.1 188589270 6320544 220414..221352 1 NC_010723.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; putative thioredoxin reductase 221352 6320544 CLH_0206 Clostridium botulinum E3 str. Alaska E43 putative thioredoxin reductase YP_001919642.1 220414 D 508767 CDS YP_001919643.1 188588465 6317612 221354..221581 1 NC_010723.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02196; hypothetical protein 221581 6317612 CLH_0207 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919643.1 221354 D 508767 CDS YP_001919644.1 188589032 6319875 complement(221821..222048) 1 NC_010723.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02196; hypothetical protein 222048 6319875 CLH_0208 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919644.1 221821 R 508767 CDS YP_001919645.1 188588338 6319755 complement(222116..222283) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 222283 6319755 CLH_0209 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919645.1 222116 R 508767 CDS YP_001919646.1 188590035 6320569 222550..223917 1 NC_010723.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 223917 radA 6320569 radA Clostridium botulinum E3 str. Alaska E43 DNA repair protein RadA YP_001919646.1 222550 D 508767 CDS YP_001919647.1 188589352 6318313 223935..224999 1 NC_010723.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 224999 6318313 CLH_0211 Clostridium botulinum E3 str. Alaska E43 DNA integrity scanning protein DisA YP_001919647.1 223935 D 508767 CDS YP_001919648.1 188588500 6318698 complement(225043..225441) 1 NC_010723.1 hypothetical protein 225441 6318698 CLH_0212 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919648.1 225043 R 508767 CDS YP_001919649.1 188587575 6320460 225704..226798 1 NC_010723.1 identified by match to protein family HMM PF01850; match to protein family HMM PF01938; pin/tram domain-containing protein 226798 6320460 CLH_0213 Clostridium botulinum E3 str. Alaska E43 pin/tram domain-containing protein YP_001919649.1 225704 D 508767 CDS YP_001919650.1 188588537 6317915 226817..227491 1 NC_010723.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 227491 ispD 6317915 ispD Clostridium botulinum E3 str. Alaska E43 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001919650.1 226817 D 508767 CDS YP_001919651.1 188587611 6318469 227814..229526 1 NC_010723.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 229526 proS 6318469 proS Clostridium botulinum E3 str. Alaska E43 prolyl-tRNA synthetase YP_001919651.1 227814 D 508767 CDS YP_001919652.1 188590724 6319527 229546..230958 1 NC_010723.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 230958 cysS 6319527 cysS Clostridium botulinum E3 str. Alaska E43 cysteinyl-tRNA synthetase YP_001919652.1 229546 D 508767 CDS YP_001919653.1 188589801 6320227 231008..231433 1 NC_010723.1 identified by match to protein family HMM PF00636; ribonuclease III 231433 6320227 CLH_0217 Clostridium botulinum E3 str. Alaska E43 ribonuclease III YP_001919653.1 231008 D 508767 CDS YP_001919654.1 188588931 6320147 231439..232311 1 NC_010723.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; TrmH family RNA methyltransferase 232311 6320147 CLH_0218 Clostridium botulinum E3 str. Alaska E43 TrmH family RNA methyltransferase YP_001919654.1 231439 D 508767 CDS YP_001919655.1 188587970 6318867 232334..232846 1 NC_010723.1 identified by match to protein family HMM PF05991; tetracycline resistance protein 232846 6318867 CLH_0219 Clostridium botulinum E3 str. Alaska E43 tetracycline resistance protein YP_001919655.1 232334 D 508767 CDS YP_001919656.1 188588004 6317664 232933..233553 1 NC_010723.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 233553 sigH 6317664 sigH Clostridium botulinum E3 str. Alaska E43 RNA polymerase factor sigma-70 YP_001919656.1 232933 D 508767 CDS YP_001919657.1 188588795 6319404 233765..234958 1 NC_010723.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 234958 tuf 6319404 tuf Clostridium botulinum E3 str. Alaska E43 elongation factor Tu YP_001919657.1 233765 D 508767 CDS YP_001919658.1 188588131 6317688 235121..235270 1 NC_010723.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 235270 rpmG 6317688 rpmG Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L33 YP_001919658.1 235121 D 508767 CDS YP_001919659.1 188588856 6319162 235320..235550 1 NC_010723.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 235550 secE 6319162 secE Clostridium botulinum E3 str. Alaska E43 preprotein translocase subunit SecE YP_001919659.1 235320 D 508767 CDS YP_001919660.1 188589977 6317759 235588..236109 1 NC_010723.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 236109 nusG 6317759 nusG Clostridium botulinum E3 str. Alaska E43 transcription antitermination protein NusG YP_001919660.1 235588 D 508767 CDS YP_001919661.1 188590698 6318333 236187..236612 1 NC_010723.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 236612 rplK 6318333 rplK Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L11 YP_001919661.1 236187 D 508767 CDS YP_001919662.1 188587702 6318008 236667..237356 1 NC_010723.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 237356 rplA 6318008 rplA Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L1 YP_001919662.1 236667 D 508767 CDS YP_001919663.1 188588432 6318452 237567..238070 1 NC_010723.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 238070 rplJ 6318452 rplJ Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L10 YP_001919663.1 237567 D 508767 CDS YP_001919664.1 188589549 6319889 238128..238490 1 NC_010723.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 238490 rplL 6319889 rplL Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L7/L12 YP_001919664.1 238128 D 508767 CDS YP_001919665.1 188588112 6320215 238856..242581 1 NC_010723.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 242581 rpoB 6320215 rpoB Clostridium botulinum E3 str. Alaska E43 DNA-directed RNA polymerase subunit beta YP_001919665.1 238856 D 508767 CDS YP_001919666.1 188590157 6319182 242603..246136 1 NC_010723.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 246136 rpoC 6319182 rpoC Clostridium botulinum E3 str. Alaska E43 DNA-directed RNA polymerase subunit beta' YP_001919666.1 242603 D 508767 CDS YP_001919667.1 188589278 6317283 246433..246810 1 NC_010723.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 246810 rpsL 6317283 rpsL Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S12 YP_001919667.1 246433 D 508767 CDS YP_001919668.1 188588584 6317595 246956..247426 1 NC_010723.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 247426 rpsG 6317595 rpsG Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S7 YP_001919668.1 246956 D 508767 CDS YP_001919669.1 188588068 6320059 247505..249571 1 NC_010723.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 249571 fusA 6320059 fusA Clostridium botulinum E3 str. Alaska E43 elongation factor G YP_001919669.1 247505 D 508767 CDS YP_001919670.1 188589870 6318990 249664..250857 1 NC_010723.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 250857 tuf 6318990 tuf Clostridium botulinum E3 str. Alaska E43 elongation factor Tu YP_001919670.1 249664 D 508767 CDS YP_001919671.1 188589142 6319791 251339..251647 1 NC_010723.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 251647 rpsJ 6319791 rpsJ Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S10 YP_001919671.1 251339 D 508767 CDS YP_001919672.1 188590013 6319167 251720..252349 1 NC_010723.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 252349 rplC 6319167 rplC Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L3 YP_001919672.1 251720 D 508767 CDS YP_001919673.1 188589298 6320381 252375..252995 1 NC_010723.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 252995 rplD 6320381 rplD Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L4 YP_001919673.1 252375 D 508767 CDS YP_001919674.1 188589372 6317319 252995..253291 1 NC_010723.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 253291 rplW 6317319 rplW Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L23 YP_001919674.1 252995 D 508767 CDS YP_001919675.1 188588649 6317846 253351..254184 1 NC_010723.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 254184 rplB 6317846 rplB Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L2 YP_001919675.1 253351 D 508767 CDS YP_001919676.1 188587932 6317587 254252..254530 1 NC_010723.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 254530 rpsS 6317587 rpsS Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S19 YP_001919676.1 254252 D 508767 CDS YP_001919677.1 188590483 6317452 254551..254886 1 NC_010723.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 254886 rplV 6317452 rplV Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L22 YP_001919677.1 254551 D 508767 CDS YP_001919678.1 188588786 6318271 254905..255570 1 NC_010723.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 255570 rpsC 6318271 rpsC Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S3 YP_001919678.1 254905 D 508767 CDS YP_001919679.1 188588061 6317974 255588..256022 1 NC_010723.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 256022 rplP 6317974 rplP Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L16 YP_001919679.1 255588 D 508767 CDS YP_001919680.1 188590632 6318471 256022..256234 1 NC_010723.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 256234 rpmC 6318471 rpmC Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L29 YP_001919680.1 256022 D 508767 CDS YP_001919681.1 188590085 6317872 256258..256512 1 NC_010723.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 256512 rpsQ 6317872 rpsQ Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S17 YP_001919681.1 256258 D 508767 CDS YP_001919682.1 188588433 6317461 256541..256909 1 NC_010723.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 256909 rplN 6317461 rplN Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L14 YP_001919682.1 256541 D 508767 CDS YP_001919683.1 188587802 6320337 256925..257239 1 NC_010723.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 257239 rplX 6320337 rplX Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L24 YP_001919683.1 256925 D 508767 CDS YP_001919684.1 188590408 6320157 257263..257802 1 NC_010723.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 257802 rplE 6320157 rplE Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L5 YP_001919684.1 257263 D 508767 CDS YP_001919685.1 188589683 6317250 257819..258004 1 NC_010723.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 258004 rpsN 6317250 rpsN Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S14 YP_001919685.1 257819 D 508767 CDS YP_001919686.1 188587694 6319421 258035..258433 1 NC_010723.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 258433 rpsH 6319421 rpsH Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S8 YP_001919686.1 258035 D 508767 CDS YP_001919687.1 188588384 6318220 258506..259048 1 NC_010723.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 259048 rplF 6318220 rplF Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L6 YP_001919687.1 258506 D 508767 CDS YP_001919688.1 188589971 6319968 259067..259426 1 NC_010723.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 259426 rplR 6319968 rplR Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L18 YP_001919688.1 259067 D 508767 CDS YP_001919689.1 188590652 6319036 259446..259943 1 NC_010723.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 259943 rpsE 6319036 rpsE Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S5 YP_001919689.1 259446 D 508767 CDS YP_001919690.1 188589442 6317979 259955..260134 1 NC_010723.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 260134 rpmD 6317979 rpmD Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L30 YP_001919690.1 259955 D 508767 CDS YP_001919691.1 188588063 6318418 260158..260598 1 NC_010723.1 late assembly protein; 50S ribosomal protein L15 260598 rplO 6318418 rplO Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L15 YP_001919691.1 260158 D 508767 CDS YP_001919692.1 188587684 6319043 260600..261880 1 NC_010723.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 261880 secY 6319043 secY Clostridium botulinum E3 str. Alaska E43 preprotein translocase subunit SecY YP_001919692.1 260600 D 508767 CDS YP_001919693.1 188588360 6318273 261905..262552 1 NC_010723.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 262552 adk 6318273 adk Clostridium botulinum E3 str. Alaska E43 adenylate kinase YP_001919693.1 261905 D 508767 CDS YP_001919694.1 188590736 6319622 262556..263305 1 NC_010723.1 identified by match to protein family HMM PF00557; match to protein family HMM TIGR00500; methionine aminopeptidase 263305 map 6319622 map Clostridium botulinum E3 str. Alaska E43 methionine aminopeptidase YP_001919694.1 262556 D 508767 CDS YP_001919695.1 188588177 6318813 263394..263675 1 NC_010723.1 hypothetical protein 263675 6318813 CLH_0260 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919695.1 263394 D 508767 CDS YP_001919696.1 188588411 6319399 263683..263901 1 NC_010723.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 263901 infA 6319399 infA Clostridium botulinum E3 str. Alaska E43 translation initiation factor IF-1 YP_001919696.1 263683 D 508767 CDS YP_001919697.1 188587709 6320009 263955..264068 1 NC_010723.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 264068 rpmJ 6320009 rpmJ Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L36 YP_001919697.1 263955 D 508767 CDS YP_001919698.1 188589031 6319591 264274..264642 1 NC_010723.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 264642 rpsM 6319591 rpsM Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S13 YP_001919698.1 264274 D 508767 CDS YP_001919699.1 188587566 6319754 264662..265054 1 NC_010723.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 265054 rpsK 6319754 rpsK Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S11 YP_001919699.1 264662 D 508767 CDS YP_001919700.1 188590506 6320275 265082..265702 1 NC_010723.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 265702 rpsD 6320275 rpsD Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S4 YP_001919700.1 265082 D 508767 CDS YP_001919701.1 188589874 6320601 265814..266761 1 NC_010723.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 266761 rpoA 6320601 rpoA Clostridium botulinum E3 str. Alaska E43 DNA-directed RNA polymerase subunit alpha YP_001919701.1 265814 D 508767 CDS YP_001919702.1 188588891 6320105 266774..267115 1 NC_010723.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 267115 rplQ 6320105 rplQ Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L17 YP_001919702.1 266774 D 508767 CDS YP_001919703.1 188587979 6317274 267368..268219 1 NC_010723.1 with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 268219 6317274 CLH_0268 Clostridium botulinum E3 str. Alaska E43 cobalt transporter ATP-binding subunit YP_001919703.1 267368 D 508767 CDS YP_001919704.1 188587864 6318888 268204..269061 1 NC_010723.1 with CbiNQ forms the ABC transporter for cobalt import; Clostridia have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 269061 cbiO 6318888 cbiO Clostridium botulinum E3 str. Alaska E43 cobalt transporter ATP-binding subunit YP_001919704.1 268204 D 508767 CDS YP_001919705.1 188590395 6317540 269153..269956 1 NC_010723.1 identified by match to protein family HMM PF02361; cobalt ABC transporter permease 269956 6317540 CLH_0270 Clostridium botulinum E3 str. Alaska E43 cobalt ABC transporter permease YP_001919705.1 269153 D 508767 CDS YP_001919706.1 188590732 6318012 269973..270707 1 NC_010723.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 270707 truA 6318012 truA Clostridium botulinum E3 str. Alaska E43 tRNA pseudouridine synthase A YP_001919706.1 269973 D 508767 CDS YP_001919707.1 188588197 6317867 270867..271301 1 NC_010723.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 271301 rplM 6317867 rplM Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L13 YP_001919707.1 270867 D 508767 CDS YP_001919708.1 188587721 6319531 271329..271721 1 NC_010723.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 271721 rpsI 6319531 rpsI Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S9 YP_001919708.1 271329 D 508767 CDS YP_001919709.1 188588413 6319063 272053..273666 1 NC_010723.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704; Na/Pi-cotransporter family protein/PhoU family protein 273666 6319063 CLH_0274 Clostridium botulinum E3 str. Alaska E43 Na/Pi-cotransporter family protein/PhoU family protein YP_001919709.1 272053 D 508767 CDS YP_001919710.1 188587636 6319733 274089..274751 1 NC_010723.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR02883; N-acetylmuramoyl-L-alanine amidase CwlD 274751 cwlD 6319733 cwlD Clostridium botulinum E3 str. Alaska E43 N-acetylmuramoyl-L-alanine amidase CwlD YP_001919710.1 274089 D 508767 CDS YP_001919711.1 188588508 6319865 complement(274967..275734) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 275734 6319865 CLH_0276 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919711.1 274967 R 508767 CDS YP_001919712.1 188589455 6318353 275869..276711 1 NC_010723.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; fumarate hydratase 276711 6318353 CLH_0277 Clostridium botulinum E3 str. Alaska E43 fumarate hydratase YP_001919712.1 275869 D 508767 CDS YP_001919713.1 188590361 6317492 277084..277641 1 NC_010723.1 Catalyzes the reversible hydration of fumaric acid to yield l-malic acid; fumarate hydratase 277641 fumB 6317492 fumB Clostridium botulinum E3 str. Alaska E43 fumarate hydratase YP_001919713.1 277084 D 508767 CDS YP_001919714.1 188587959 6317501 277654..277782 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 277782 6317501 CLH_0279 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919714.1 277654 D 508767 CDS YP_001919715.1 188589059 6317297 complement(278096..278953) 1 NC_010723.1 identified by match to protein family HMM PF02588; transporter 278953 6317297 CLH_0280 Clostridium botulinum E3 str. Alaska E43 transporter YP_001919715.1 278096 R 508767 CDS YP_001919716.1 188589679 6319347 279215..279925 1 NC_010723.1 identified by match to protein family HMM PF00515; hypothetical protein 279925 6319347 CLH_0281 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919716.1 279215 D 508767 CDS YP_001919717.1 188590423 6318057 280003..280695 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; regulatory protein VanR 280695 6318057 CLH_0282 Clostridium botulinum E3 str. Alaska E43 regulatory protein VanR YP_001919717.1 280003 D 508767 CDS YP_001919718.1 188589738 6320040 280667..282523 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; two-component sensor kinase 282523 6320040 CLH_0283 Clostridium botulinum E3 str. Alaska E43 two-component sensor kinase YP_001919718.1 280667 D 508767 CDS YP_001919719.1 188590737 6318321 282725..284950 1 NC_010723.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 284950 6318321 CLH_0284 Clostridium botulinum E3 str. Alaska E43 ribonucleotide-diphosphate reductase subunit alpha YP_001919719.1 282725 D 508767 CDS YP_001919720.1 188588149 6319270 285165..286199 1 NC_010723.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 286199 nrdF 6319270 nrdF Clostridium botulinum E3 str. Alaska E43 ribonucleotide-diphosphate reductase subunit beta YP_001919720.1 285165 D 508767 CDS YP_001919721.1 188588459 6318262 286389..288008 1 NC_010723.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 288008 ptsP 6318262 ptsP Clostridium botulinum E3 str. Alaska E43 phosphoenolpyruvate-protein phosphotransferase YP_001919721.1 286389 D 508767 CDS YP_001919722.1 188589195 6319822 288413..288946 1 NC_010723.1 identified by match to protein family HMM PF02417; chromate transport protein 288946 chrA 6319822 chrA Clostridium botulinum E3 str. Alaska E43 chromate transport protein YP_001919722.1 288413 D 508767 CDS YP_001919723.1 188590326 6319047 288950..289474 1 NC_010723.1 identified by match to protein family HMM PF02417; putative chromate transport protein 289474 6319047 CLH_0288 Clostridium botulinum E3 str. Alaska E43 putative chromate transport protein YP_001919723.1 288950 D 508767 CDS YP_001919724.1 188587830 6319038 289637..290908 1 NC_010723.1 identified by match to protein family HMM PF00515; hypothetical protein 290908 6319038 CLH_0289 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919724.1 289637 D 508767 CDS YP_001919725.1 188589769 6317403 290952..292124 1 NC_010723.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR01975; isoaspartyl dipeptidase 292124 iadA 6317403 iadA Clostridium botulinum E3 str. Alaska E43 isoaspartyl dipeptidase YP_001919725.1 290952 D 508767 CDS YP_001919726.1 188589156 6319730 complement(292227..292856) 1 NC_010723.1 identified by match to protein family HMM PF07486; spore-cortex-lytic enzyme, sleb 292856 6319730 CLH_0291 Clostridium botulinum E3 str. Alaska E43 spore-cortex-lytic enzyme, sleb YP_001919726.1 292227 R 508767 CDS YP_001919727.1 188589714 6320189 complement(292926..293912) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 293912 6320189 CLH_0292 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919727.1 292926 R 508767 CDS YP_001919728.1 188590430 6320405 294096..294956 1 NC_010723.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159; hypothetical protein 294956 6320405 CLH_0293 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919728.1 294096 D 508767 CDS YP_001919729.1 188589706 6320478 294926..296149 1 NC_010723.1 identified by match to protein family HMM PF07949; hypothetical protein 296149 6320478 CLH_0294 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919729.1 294926 D 508767 CDS YP_001919730.1 188590514 6318429 296253..297848 1 NC_010723.1 identified by match to protein family HMM PF03486; match to protein family HMM PF07992; oxidoreductase, FAD-binding 297848 6318429 CLH_0295 Clostridium botulinum E3 str. Alaska E43 oxidoreductase, FAD-binding YP_001919730.1 296253 D 508767 CDS YP_001919731.1 188588715 6319152 298022..298930 1 NC_010723.1 catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate; phosphate butyryltransferase 298930 ptb 6319152 ptb Clostridium botulinum E3 str. Alaska E43 phosphate butyryltransferase YP_001919731.1 298022 D 508767 CDS YP_001919732.1 188589359 6317765 298954..300021 1 NC_010723.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase 300021 buk 6317765 buk Clostridium botulinum E3 str. Alaska E43 butyrate kinase YP_001919732.1 298954 D 508767 CDS YP_001919733.1 188590073 6318095 300407..301240 1 NC_010723.1 identified by match to protein family HMM PF01987; HTH DNA-binding protein 301240 6318095 CLH_0298 Clostridium botulinum E3 str. Alaska E43 HTH DNA-binding protein YP_001919733.1 300407 D 508767 CDS YP_001919734.1 188588350 6317798 301323..301619 1 NC_010723.1 identified by match to protein family HMM PF01371; match to protein family HMM TIGR02531; TrpR-like protein 301619 6317798 CLH_0299 Clostridium botulinum E3 str. Alaska E43 TrpR-like protein YP_001919734.1 301323 D 508767 CDS YP_001919735.1 188588959 6319707 301909..303252 1 NC_010723.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 303252 glmM 6319707 glmM Clostridium botulinum E3 str. Alaska E43 phosphoglucosamine mutase YP_001919735.1 301909 D 508767 CDS YP_001919736.1 188587869 6317479 303608..304021 1 NC_010723.1 hypothetical protein 304021 6317479 CLH_0301 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919736.1 303608 D 508767 CDS YP_001919737.1 188588589 6318728 304556..305065 1 NC_010723.1 identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119; acetolactate synthase small subunit 305065 ilvN 6318728 ilvN Clostridium botulinum E3 str. Alaska E43 acetolactate synthase small subunit YP_001919737.1 304556 D 508767 CDS YP_001919738.1 188587921 6318029 305239..306498 1 NC_010723.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; 3-isopropylmalate dehydratase large subunit 306498 leuC 6318029 leuC Clostridium botulinum E3 str. Alaska E43 3-isopropylmalate dehydratase large subunit YP_001919738.1 305239 D 508767 CDS YP_001919739.1 188590474 6320156 306514..306999 1 NC_010723.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; 3-isopropylmalate dehydratase small subunit 306999 leuD 6320156 leuD Clostridium botulinum E3 str. Alaska E43 3-isopropylmalate dehydratase small subunit YP_001919739.1 306514 D 508767 CDS YP_001919740.1 188589773 6320441 307169..308251 1 NC_010723.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 308251 leuB 6320441 leuB Clostridium botulinum E3 str. Alaska E43 3-isopropylmalate dehydrogenase YP_001919740.1 307169 D 508767 CDS YP_001919741.1 188589105 6320254 308258..309916 1 NC_010723.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 309916 ilvD 6320254 ilvD Clostridium botulinum E3 str. Alaska E43 dihydroxy-acid dehydratase YP_001919741.1 308258 D 508767 CDS YP_001919742.1 188588314 6320564 309956..311629 1 NC_010723.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase large subunit 311629 ilvB 6320564 ilvB Clostridium botulinum E3 str. Alaska E43 acetolactate synthase large subunit YP_001919742.1 309956 D 508767 CDS YP_001919743.1 188587678 6319983 311650..312666 1 NC_010723.1 identified by match to protein family HMM PF01450; match to protein family HMM PF07991; match to protein family HMM TIGR00465; ketol-acid reductoisomerase 312666 ilvC 6319983 ilvC Clostridium botulinum E3 str. Alaska E43 ketol-acid reductoisomerase YP_001919743.1 311650 D 508767 CDS YP_001919744.1 188590227 6318560 312752..312871 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 312871 6318560 CLH_0309 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919744.1 312752 D 508767 CDS YP_001919745.1 188587548 6320469 complement(312951..314840) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC-type multidrug/protein/lipid transport system, ATPase 314840 6320469 CLH_0310 Clostridium botulinum E3 str. Alaska E43 ABC-type multidrug/protein/lipid transport system, ATPase YP_001919745.1 312951 R 508767 CDS YP_001919746.1 188589746 6319081 complement(314833..316566) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 316566 6319081 CLH_0311 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001919746.1 314833 R 508767 CDS YP_001919747.1 188587660 6320435 complement(316620..317063) 1 NC_010723.1 identified by match to protein family HMM PF01047; MarR-family transcriptional regulator 317063 6320435 CLH_0312 Clostridium botulinum E3 str. Alaska E43 MarR-family transcriptional regulator YP_001919747.1 316620 R 508767 CDS YP_001919748.1 188588148 6319601 317452..317709 1 NC_010723.1 identified by match to protein family HMM PF01541; GIY-YIG domain-containing protein 317709 6319601 CLH_0313 Clostridium botulinum E3 str. Alaska E43 GIY-YIG domain-containing protein YP_001919748.1 317452 D 508767 CDS YP_001919749.1 188588763 6318261 317753..318751 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator, LacI family 318751 6318261 CLH_0314 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, LacI family YP_001919749.1 317753 D 508767 CDS YP_001919750.1 188587622 6319097 319065..320729 1 NC_010723.1 identified by match to protein family HMM PF00128; glycosyl hydrolase family protein 320729 6319097 CLH_0315 Clostridium botulinum E3 str. Alaska E43 glycosyl hydrolase family protein YP_001919750.1 319065 D 508767 CDS YP_001919751.1 188590568 6319907 320821..322479 1 NC_010723.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR02003; pts system, iibc component 322479 6319907 CLH_0316 Clostridium botulinum E3 str. Alaska E43 pts system, iibc component YP_001919751.1 320821 D 508767 CDS YP_001919752.1 188589668 6320229 322484..323272 1 NC_010723.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family protein 323272 6320229 CLH_0317 Clostridium botulinum E3 str. Alaska E43 endonuclease/exonuclease/phosphatase family protein YP_001919752.1 322484 D 508767 CDS YP_001919753.1 188589855 6320135 complement(323315..323806) 1 NC_010723.1 identified by match to protein family HMM PF01047; MarR-family transcriptional regulator 323806 6320135 CLH_0318 Clostridium botulinum E3 str. Alaska E43 MarR-family transcriptional regulator YP_001919753.1 323315 R 508767 CDS YP_001919754.1 188588950 6320096 324106..325332 1 NC_010723.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; RND family efflux transporter MFP subunit 325332 6320096 CLH_0319 Clostridium botulinum E3 str. Alaska E43 RND family efflux transporter MFP subunit YP_001919754.1 324106 D 508767 CDS YP_001919755.1 188590039 6318414 325337..328540 1 NC_010723.1 identified by match to protein family HMM PF00873; putative multidrug efflux pump, membrane protein 328540 6318414 CLH_0320 Clostridium botulinum E3 str. Alaska E43 putative multidrug efflux pump, membrane protein YP_001919755.1 325337 D 508767 CDS YP_001919756.1 188589475 6319412 328567..329724 1 NC_010723.1 putative multidrug efflux pump, outer membrane protein 329724 6319412 CLH_0321 Clostridium botulinum E3 str. Alaska E43 putative multidrug efflux pump, outer membrane protein YP_001919756.1 328567 D 508767 CDS YP_001919757.1 188590244 6317279 330235..331281 1 NC_010723.1 identified by match to protein family HMM PF01473; S-layer protein 331281 6317279 CLH_0322 Clostridium botulinum E3 str. Alaska E43 S-layer protein YP_001919757.1 330235 D 508767 CDS YP_001919758.1 188589424 6320576 332070..333896 1 NC_010723.1 identified by match to protein family HMM PF00310; match to protein family HMM PF01380; match to protein family HMM TIGR01135; glutamine-fructose-6-phosphate transaminase (isomerizing) 333896 glmS 6320576 glmS Clostridium botulinum E3 str. Alaska E43 glutamine-fructose-6-phosphate transaminase (isomerizing) YP_001919758.1 332070 D 508767 CDS YP_001919759.1 188589088 6317609 334084..334758 1 NC_010723.1 identified by match to protein family HMM PF00027; cyclic nucleotide-binding domain-containing protein 334758 6317609 CLH_0324 Clostridium botulinum E3 str. Alaska E43 cyclic nucleotide-binding domain-containing protein YP_001919759.1 334084 D 508767 CDS YP_001919760.1 188587736 6319154 335012..336355 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 336355 6319154 CLH_0325 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001919760.1 335012 D 508767 CDS YP_001919761.1 188590559 6319471 336836..338359 1 NC_010723.1 identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphoglucomutase/phosphomannomutase family protein 338359 6319471 CLH_0326 Clostridium botulinum E3 str. Alaska E43 phosphoglucomutase/phosphomannomutase family protein YP_001919761.1 336836 D 508767 CDS YP_001919762.1 188589838 6318784 338679..340091 1 NC_010723.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 340091 6318784 CLH_0327 Clostridium botulinum E3 str. Alaska E43 potassium/proton antiporter YP_001919762.1 338679 D 508767 CDS YP_001919763.1 188589561 6320142 340697..341458 1 NC_010723.1 identified by match to protein family HMM PF01226; formate/nitrite transporter family protein 341458 6320142 CLH_0328 Clostridium botulinum E3 str. Alaska E43 formate/nitrite transporter family protein YP_001919763.1 340697 D 508767 CDS YP_001919764.1 188588018 6318316 341617..342021 1 NC_010723.1 hypothetical protein 342021 6318316 CLH_0329 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919764.1 341617 D 508767 CDS YP_001919765.1 188589913 6319409 complement(342099..342659) 1 NC_010723.1 identified by match to protein family HMM PF00484; carbonate dehydratase 342659 6319409 CLH_0330 Clostridium botulinum E3 str. Alaska E43 carbonate dehydratase YP_001919765.1 342099 R 508767 CDS YP_001919766.1 188590747 6319546 342908..343489 1 NC_010723.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; 5-formyltetrahydrofolate cyclo-ligase 343489 6319546 CLH_0331 Clostridium botulinum E3 str. Alaska E43 5-formyltetrahydrofolate cyclo-ligase YP_001919766.1 342908 D 508767 CDS YP_001919767.1 188589271 6318092 343819..345084 1 NC_010723.1 identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326; O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein 345084 6318092 CLH_0332 Clostridium botulinum E3 str. Alaska E43 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein YP_001919767.1 343819 D 508767 CDS YP_001919768.1 188588550 6317613 complement(345312..347243) 1 NC_010723.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 347243 thrS 6317613 thrS Clostridium botulinum E3 str. Alaska E43 threonyl-tRNA synthetase YP_001919768.1 345312 R 508767 CDS YP_001919769.1 188588374 6318361 complement(347638..348051) 1 NC_010723.1 hypothetical protein 348051 6318361 CLH_0334 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919769.1 347638 R 508767 CDS YP_001919770.1 188587857 6320005 348307..348867 1 NC_010723.1 identified by match to protein family HMM PF04309; glycerol-3-phosphate responsive antiterminator 348867 6320005 CLH_0335 Clostridium botulinum E3 str. Alaska E43 glycerol-3-phosphate responsive antiterminator YP_001919770.1 348307 D 508767 CDS YP_001919771.1 188590284 6317418 348979..350307 1 NC_010723.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00881; glycerol-3-phosphate transporter 350307 6317418 CLH_0336 Clostridium botulinum E3 str. Alaska E43 glycerol-3-phosphate transporter YP_001919771.1 348979 D 508767 CDS YP_001919772.1 188588932 6320598 350737..351333 1 NC_010723.1 hypothetical protein 351333 6320598 CLH_0337 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919772.1 350737 D 508767 CDS YP_001919773.1 188588935 6317672 complement(351409..351882) 1 NC_010723.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 351882 ispF 6317672 ispF Clostridium botulinum E3 str. Alaska E43 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001919773.1 351409 R 508767 CDS YP_001919774.1 188588023 6318959 352176..352298 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 352298 6318959 CLH_0339 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919774.1 352176 D 508767 CDS YP_001919775.1 188590684 6319224 352336..353367 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 353367 6319224 CLH_0340 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919775.1 352336 D 508767 CDS YP_001919776.1 188588283 6320326 complement(353552..354475) 1 NC_010723.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 354475 6320326 CLH_0341 Clostridium botulinum E3 str. Alaska E43 polysaccharide deacetylase family protein YP_001919776.1 353552 R 508767 CDS YP_001919777.1 188589318 6319809 354719..355438 1 NC_010723.1 hypothetical protein 355438 6319809 CLH_0342 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919777.1 354719 D 508767 CDS YP_001919778.1 188588750 6317627 355505..356353 1 NC_010723.1 identified by match to protein family HMM PF02588; transporter 356353 6317627 CLH_0343 Clostridium botulinum E3 str. Alaska E43 transporter YP_001919778.1 355505 D 508767 CDS YP_001919779.1 188590441 6317544 complement(356604..357650) 1 NC_010723.1 catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 357650 6317544 CLH_0344 Clostridium botulinum E3 str. Alaska E43 biotin synthase YP_001919779.1 356604 R 508767 CDS YP_001919780.1 188589739 6318911 complement(357758..360427) 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; cation-transporting ATPase, P-type 360427 6318911 CLH_0345 Clostridium botulinum E3 str. Alaska E43 cation-transporting ATPase, P-type YP_001919780.1 357758 R 508767 CDS YP_001919781.1 188589734 6318322 360803..361501 1 NC_010723.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; FadR family transcriptional regulator 361501 6318322 CLH_0346 Clostridium botulinum E3 str. Alaska E43 FadR family transcriptional regulator YP_001919781.1 360803 D 508767 CDS YP_001919782.1 188588960 6319692 361901..362167 1 NC_010723.1 L-lactate permease 362167 lctP 6319692 lctP Clostridium botulinum E3 str. Alaska E43 L-lactate permease YP_001919782.1 361901 D 508767 CDS YP_001919783.1 188588262 6317480 362333..363121 1 NC_010723.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein, beta subunit/FixA family protein 363121 6317480 CLH_0348 Clostridium botulinum E3 str. Alaska E43 electron transfer flavoprotein, beta subunit/FixA family protein YP_001919783.1 362333 D 508767 CDS YP_001919784.1 188590215 6319856 363224..364414 1 NC_010723.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein, alpha subunit/FixB family protein 364414 6319856 CLH_0349 Clostridium botulinum E3 str. Alaska E43 electron transfer flavoprotein, alpha subunit/FixB family protein YP_001919784.1 363224 D 508767 CDS YP_001919785.1 188588026 6317574 364419..365822 1 NC_010723.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD/FMN-containing dehydrogenase 365822 6317574 CLH_0350 Clostridium botulinum E3 str. Alaska E43 FAD/FMN-containing dehydrogenase YP_001919785.1 364419 D 508767 CDS YP_001919786.1 188587954 6318646 367280..367723 1 NC_010723.1 L-lactate permease 367723 lctP 6318646 lctP Clostridium botulinum E3 str. Alaska E43 L-lactate permease YP_001919786.1 367280 D 508767 CDS YP_001919787.1 188588456 6317270 367960..368802 1 NC_010723.1 identified by match to protein family HMM PF01734; phospholipase, patatin family 368802 6317270 CLH_0354 Clostridium botulinum E3 str. Alaska E43 phospholipase, patatin family YP_001919787.1 367960 D 508767 CDS YP_001919788.1 188589823 6318709 368971..370185 1 NC_010723.1 identified by match to protein family HMM PF02810; SEC-C motif domain protein 370185 6318709 CLH_0355 Clostridium botulinum E3 str. Alaska E43 SEC-C motif domain protein YP_001919788.1 368971 D 508767 CDS YP_001919789.1 188590368 6318480 370400..371467 1 NC_010723.1 identified by match to protein family HMM PF00483; putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 371467 6318480 CLH_0356 Clostridium botulinum E3 str. Alaska E43 putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_001919789.1 370400 D 508767 CDS YP_001919790.1 188587602 6318292 371741..372322 1 NC_010723.1 hypothetical protein 372322 6318292 CLH_0357 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919790.1 371741 D 508767 CDS YP_001919791.1 188588006 6319640 372447..372812 1 NC_010723.1 identified by match to protein family HMM PF01022; cadmium efflux system accessory protein 372812 6319640 CLH_0358 Clostridium botulinum E3 str. Alaska E43 cadmium efflux system accessory protein YP_001919791.1 372447 D 508767 CDS YP_001919792.1 188588897 6319562 372830..375091 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525; cadmium-translocating P-type ATPase 375091 cadA 6319562 cadA Clostridium botulinum E3 str. Alaska E43 cadmium-translocating P-type ATPase YP_001919792.1 372830 D 508767 CDS YP_001919793.1 188589973 6319367 375524..376156 1 NC_010723.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 376156 6319367 CLH_0360 Clostridium botulinum E3 str. Alaska E43 redox-sensing transcriptional repressor Rex YP_001919793.1 375524 D 508767 CDS YP_001919794.1 188588574 6319164 376505..377287 1 NC_010723.1 catalyzes the formation of crotonoyl-CoA from (3R)-3-hydroxybutanoyl-CoA; 3-hydroxybutyryl-CoA dehydratase 377287 crt 6319164 crt Clostridium botulinum E3 str. Alaska E43 3-hydroxybutyryl-CoA dehydratase YP_001919794.1 376505 D 508767 CDS YP_001919795.1 188588331 6319437 377368..378507 1 NC_010723.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-coa dehydrogenase, short-chain specific 378507 6319437 CLH_0362 Clostridium botulinum E3 str. Alaska E43 acyl-coa dehydrogenase, short-chain specific YP_001919795.1 377368 D 508767 CDS YP_001919796.1 188590762 6320028 378525..379307 1 NC_010723.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein, beta subunit/FixA family protein 379307 6320028 CLH_0363 Clostridium botulinum E3 str. Alaska E43 electron transfer flavoprotein, beta subunit/FixA family protein YP_001919796.1 378525 D 508767 CDS YP_001919797.1 188589707 6320165 379330..380337 1 NC_010723.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein subunit alpha 380337 etfA 6320165 etfA Clostridium botulinum E3 str. Alaska E43 electron transfer flavoprotein subunit alpha YP_001919797.1 379330 D 508767 CDS YP_001919798.1 188588994 6318430 380441..381289 1 NC_010723.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 381289 6318430 CLH_0365 Clostridium botulinum E3 str. Alaska E43 3-hydroxybutyryl-CoA dehydrogenase YP_001919798.1 380441 D 508767 CDS YP_001919799.1 188589562 6319439 381449..381883 1 NC_010723.1 identified by match to protein family HMM PF09719; match to protein family HMM TIGR01909; hypothetical protein 381883 6319439 CLH_0366 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919799.1 381449 D 508767 CDS YP_001919800.1 188590592 6317475 381973..382899 1 NC_010723.1 identified by match to protein family HMM PF00730; match to protein family HMM PF07934; 8-oxoguanine DNA glycosylase 382899 6317475 CLH_0367 Clostridium botulinum E3 str. Alaska E43 8-oxoguanine DNA glycosylase YP_001919800.1 381973 D 508767 CDS YP_001919801.1 188587767 6318409 383061..384545 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02906; iron-dependent hydrogenase 384545 6318409 CLH_0368 Clostridium botulinum E3 str. Alaska E43 iron-dependent hydrogenase YP_001919801.1 383061 D 508767 CDS YP_001919802.1 188588682 6319386 384744..385439 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 385439 6319386 CLH_0369 Clostridium botulinum E3 str. Alaska E43 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_001919802.1 384744 D 508767 CDS YP_001919803.1 188588850 6318444 385443..386858 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; two-component sensor histidine kinase 386858 6318444 CLH_0370 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001919803.1 385443 D 508767 CDS YP_001919804.1 188587985 6319196 386883..387722 1 NC_010723.1 hypothetical protein 387722 6319196 CLH_0371 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919804.1 386883 D 508767 CDS YP_001919805.1 188588915 6319014 387743..388792 1 NC_010723.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 388792 6319014 CLH_0372 Clostridium botulinum E3 str. Alaska E43 ABC transporter substrate-binding protein YP_001919805.1 387743 D 508767 CDS YP_001919806.1 188589840 6317899 389196..389480 1 NC_010723.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 389480 groES 6317899 groES Clostridium botulinum E3 str. Alaska E43 co-chaperonin GroES YP_001919806.1 389196 D 508767 CDS YP_001919807.1 188590668 6317585 389494..391116 1 NC_010723.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 391116 groEL 6317585 groEL Clostridium botulinum E3 str. Alaska E43 chaperonin GroEL YP_001919807.1 389494 D 508767 CDS YP_001919808.1 188587751 6318793 391329..391733 1 NC_010723.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; putative pilin 391733 6318793 CLH_0375 Clostridium botulinum E3 str. Alaska E43 putative pilin YP_001919808.1 391329 D 508767 CDS YP_001919809.1 188588749 6318657 392068..393522 1 NC_010723.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 393522 guaB 6318657 guaB Clostridium botulinum E3 str. Alaska E43 inosine 5'-monophosphate dehydrogenase YP_001919809.1 392068 D 508767 CDS YP_001919810.1 188589233 6317543 393609..395150 1 NC_010723.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 395150 guaA 6317543 guaA Clostridium botulinum E3 str. Alaska E43 GMP synthase YP_001919810.1 393609 D 508767 CDS YP_001919811.1 188589620 6317828 395463..396626 1 NC_010723.1 FliB domain-containing protein 396626 6317828 CLH_0378 Clostridium botulinum E3 str. Alaska E43 FliB domain-containing protein YP_001919811.1 395463 D 508767 CDS YP_001919812.1 188587829 6320304 396698..397543 1 NC_010723.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 397543 6320304 CLH_0379 Clostridium botulinum E3 str. Alaska E43 polysaccharide deacetylase family protein YP_001919812.1 396698 D 508767 CDS YP_001919813.1 188588340 6317402 397768..398217 1 NC_010723.1 hypothetical protein 398217 6317402 CLH_0380 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919813.1 397768 D 508767 CDS YP_001919814.1 188589158 6318363 398531..400495 1 NC_010723.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279; putative transcription antiterminator 400495 6318363 CLH_0381 Clostridium botulinum E3 str. Alaska E43 putative transcription antiterminator YP_001919814.1 398531 D 508767 CDS YP_001919815.1 188588231 6319431 400499..400915 1 NC_010723.1 identified by match to protein family HMM PF06923; glucitol operon activator protein 400915 6319431 CLH_0382 Clostridium botulinum E3 str. Alaska E43 glucitol operon activator protein YP_001919815.1 400499 D 508767 CDS YP_001919816.1 188590582 6319613 400947..401507 1 NC_010723.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821; PTS system, glucitol/sorbitol-specific, IIC component 401507 6319613 CLH_0383 Clostridium botulinum E3 str. Alaska E43 PTS system, glucitol/sorbitol-specific, IIC component YP_001919816.1 400947 D 508767 CDS YP_001919817.1 188590365 6319383 401604..401975 1 NC_010723.1 identified by match to protein family HMM PF03612; glucitol/sorbitol-specific phosphotransferase enzyme iib component 401975 6319383 CLH_0384 Clostridium botulinum E3 str. Alaska E43 glucitol/sorbitol-specific phosphotransferase enzyme iib component YP_001919817.1 401604 D 508767 CDS YP_001919818.1 188590745 6320529 402024..402590 1 NC_010723.1 identified by match to protein family HMM PF07663; PTS system, glucitol/sorbitol-specific, IIBC component 402590 6320529 CLH_0385 Clostridium botulinum E3 str. Alaska E43 PTS system, glucitol/sorbitol-specific, IIBC component YP_001919818.1 402024 D 508767 CDS YP_001919819.1 188588553 6318182 402637..403002 1 NC_010723.1 identified by match to protein family HMM PF03829; putative PTS system, glucitol/sorbitol-specific IIA component 403002 6318182 CLH_0386 Clostridium botulinum E3 str. Alaska E43 putative PTS system, glucitol/sorbitol-specific IIA component YP_001919819.1 402637 D 508767 CDS YP_001919820.1 188587863 6318347 403269..404090 1 NC_010723.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 404090 6318347 CLH_0387 Clostridium botulinum E3 str. Alaska E43 sorbitol-6-phosphate 2-dehydrogenase YP_001919820.1 403269 D 508767 CDS YP_001919821.1 188590431 6319445 404250..404918 1 NC_010723.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00875; putative transaldolase 404918 6319445 CLH_0388 Clostridium botulinum E3 str. Alaska E43 putative transaldolase YP_001919821.1 404250 D 508767 CDS YP_001919822.1 188589685 6320501 405120..406469 1 NC_010723.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 406469 pgi 6320501 pgi Clostridium botulinum E3 str. Alaska E43 glucose-6-phosphate isomerase YP_001919822.1 405120 D 508767 CDS YP_001919823.1 188587901 6319989 406473..406919 1 NC_010723.1 identified by match to protein family HMM PF02639; hypothetical protein 406919 6319989 CLH_0390 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919823.1 406473 D 508767 CDS YP_001919824.1 188589301 6317312 407067..409097 1 NC_010723.1 identified by match to protein family HMM PF07495; triple tyrosine motif-containing protein 409097 6317312 CLH_0391 Clostridium botulinum E3 str. Alaska E43 triple tyrosine motif-containing protein YP_001919824.1 407067 D 508767 CDS YP_001919825.1 188588623 6319926 409276..410016 1 NC_010723.1 identified by match to protein family HMM PF01464; lytic murein transglycosylase 410016 6319926 CLH_0392 Clostridium botulinum E3 str. Alaska E43 lytic murein transglycosylase YP_001919825.1 409276 D 508767 CDS YP_001919826.1 188587870 6318539 410232..410948 1 NC_010723.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; RNA pseudouridine synthase family protein 410948 6318539 CLH_0393 Clostridium botulinum E3 str. Alaska E43 RNA pseudouridine synthase family protein YP_001919826.1 410232 D 508767 CDS YP_001919827.1 188588674 6318729 411482..413731 1 NC_010723.1 identified by match to protein family HMM PF00580; ATP-dependent DNA helicase PcrA 413731 6318729 CLH_0394 Clostridium botulinum E3 str. Alaska E43 ATP-dependent DNA helicase PcrA YP_001919827.1 411482 D 508767 CDS YP_001919828.1 188587790 6318821 413814..415817 1 NC_010723.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 415817 ligA 6318821 ligA Clostridium botulinum E3 str. Alaska E43 NAD-dependent DNA ligase LigA YP_001919828.1 413814 D 508767 CDS YP_001919829.1 188590701 6320578 415967..416089 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 416089 6320578 CLH_0396 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919829.1 415967 D 508767 CDS YP_001919830.1 188589621 6318404 416187..416480 1 NC_010723.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 416480 gatC 6318404 gatC Clostridium botulinum E3 str. Alaska E43 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_001919830.1 416187 D 508767 CDS YP_001919831.1 188587642 6320305 416499..417956 1 NC_010723.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 417956 gatA 6320305 gatA Clostridium botulinum E3 str. Alaska E43 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001919831.1 416499 D 508767 CDS YP_001919832.1 188588347 6319467 417977..419407 1 NC_010723.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 419407 gatB 6319467 gatB Clostridium botulinum E3 str. Alaska E43 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001919832.1 417977 D 508767 CDS YP_001919833.1 188589504 6318165 complement(419468..419767) 1 NC_010723.1 hypothetical protein 419767 6318165 CLH_0400 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919833.1 419468 R 508767 CDS YP_001919834.1 188590379 6318939 420025..421506 1 NC_010723.1 identified by match to protein family HMM PF00496; putative extracellular solute-binding protein 421506 6318939 CLH_0401 Clostridium botulinum E3 str. Alaska E43 putative extracellular solute-binding protein YP_001919834.1 420025 D 508767 CDS YP_001919835.1 188590782 6318055 complement(421579..423216) 1 NC_010723.1 hypothetical protein 423216 6318055 CLH_0402 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919835.1 421579 R 508767 CDS YP_001919836.1 188588196 6319100 423461..424210 1 NC_010723.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 424210 rph 6319100 rph Clostridium botulinum E3 str. Alaska E43 ribonuclease PH YP_001919836.1 423461 D 508767 CDS YP_001919837.1 188587875 6319402 424214..424831 1 NC_010723.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 424831 rdgB 6319402 rdgB Clostridium botulinum E3 str. Alaska E43 putative deoxyribonucleotide triphosphate pyrophosphatase YP_001919837.1 424214 D 508767 CDS YP_001919838.1 188588911 6317734 424843..425322 1 NC_010723.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase, family 425322 6317734 CLH_0405 Clostridium botulinum E3 str. Alaska E43 phosphodiesterase, family YP_001919838.1 424843 D 508767 CDS YP_001919839.1 188589374 6317698 425646..425774 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 425774 6317698 CLH_0408 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919839.1 425646 D 508767 CDS YP_001919840.1 188590006 6317943 427921..428043 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 428043 6317943 CLH_0427 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919840.1 427921 D 508767 CDS YP_001919841.1 188588212 6320475 428381..428827 1 NC_010723.1 identified by match to protein family HMM PF01431; endothelin-converting enzyme 1 428827 6320475 CLH_0428 Clostridium botulinum E3 str. Alaska E43 endothelin-converting enzyme 1 YP_001919841.1 428381 D 508767 CDS YP_001919842.1 188589379 6319686 428828..428962 1 NC_010723.1 endothelin-converting protein 1 428962 6319686 CLH_0429 Clostridium botulinum E3 str. Alaska E43 endothelin-converting protein 1 YP_001919842.1 428828 D 508767 CDS YP_001919843.1 188588042 6318823 434492..435439 1 NC_010723.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 435439 6318823 CLH_0435 Clostridium botulinum E3 str. Alaska E43 polysaccharide deacetylase family protein YP_001919843.1 434492 D 508767 CDS YP_001919844.1 188588940 6318509 435541..436230 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 436230 6318509 CLH_0436 Clostridium botulinum E3 str. Alaska E43 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_001919844.1 435541 D 508767 CDS YP_001919845.1 188589936 6318918 436235..437632 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; alkaline phosphatase synthesis sensor protein PhoR 437632 6318918 CLH_0437 Clostridium botulinum E3 str. Alaska E43 alkaline phosphatase synthesis sensor protein PhoR YP_001919845.1 436235 D 508767 CDS YP_001919846.1 188589873 6319938 437629..439086 1 NC_010723.1 putative lipoprotein 439086 6319938 CLH_0438 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001919846.1 437629 D 508767 CDS YP_001919847.1 188590723 6320104 439374..440756 1 NC_010723.1 identified by match to protein family HMM PF01523; TldD protein 440756 6320104 CLH_0439 Clostridium botulinum E3 str. Alaska E43 TldD protein YP_001919847.1 439374 D 508767 CDS YP_001919848.1 188587556 6320226 440760..442103 1 NC_010723.1 identified by match to protein family HMM PF01523; TldD/PmbA family protein 442103 6320226 CLH_0440 Clostridium botulinum E3 str. Alaska E43 TldD/PmbA family protein YP_001919848.1 440760 D 508767 CDS YP_001919849.1 188588656 6318379 complement(442457..444307) 1 NC_010723.1 identified by match to protein family HMM PF00884; sulfatase 444307 6318379 CLH_0441 Clostridium botulinum E3 str. Alaska E43 sulfatase YP_001919849.1 442457 R 508767 CDS YP_001919850.1 188588084 6317730 444491..445069 1 NC_010723.1 hypothetical protein 445069 6317730 CLH_0442 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919850.1 444491 D 508767 CDS YP_001919851.1 188589991 6318694 445100..446056 1 NC_010723.1 identified by match to protein family HMM PF01134; match to protein family HMM PF07992; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 446056 gidA 6318694 gidA Clostridium botulinum E3 str. Alaska E43 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001919851.1 445100 D 508767 CDS YP_001919852.1 188588829 6318972 complement(446053..446616) 1 NC_010723.1 identified by match to protein family HMM PF00657; putative esterase 446616 6318972 CLH_0443 Clostridium botulinum E3 str. Alaska E43 putative esterase YP_001919852.1 446053 R 508767 CDS YP_001919853.1 188589835 6318144 complement(446630..447247) 1 NC_010723.1 identified by match to protein family HMM PF05866; endodeoxyribonuclease RusA family 447247 6318144 CLH_0445 Clostridium botulinum E3 str. Alaska E43 endodeoxyribonuclease RusA family YP_001919853.1 446630 R 508767 CDS YP_001919854.1 188588889 6320021 447563..448585 1 NC_010723.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 448585 6320021 CLH_0446 Clostridium botulinum E3 str. Alaska E43 putative DNA-binding/iron metalloprotein/AP endonuclease YP_001919854.1 447563 D 508767 CDS YP_001919855.1 188588092 6320325 448588..449592 1 NC_010723.1 hypothetical protein 449592 6320325 CLH_0447 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919855.1 448588 D 508767 CDS YP_001919856.1 188589617 6319880 449756..450943 1 NC_010723.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; trypsin domain-containing protein 450943 6319880 CLH_0448 Clostridium botulinum E3 str. Alaska E43 trypsin domain-containing protein YP_001919856.1 449756 D 508767 CDS YP_001919857.1 188588748 6319139 451107..451526 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 451526 6319139 CLH_0449 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919857.1 451107 D 508767 CDS YP_001919858.1 188587818 6317451 451851..452933 1 NC_010723.1 identified by match to protein family HMM PF04346; ethanolamine transporter 452933 6317451 CLH_0450 Clostridium botulinum E3 str. Alaska E43 ethanolamine transporter YP_001919858.1 451851 D 508767 CDS YP_001919859.1 188590167 6318391 452959..454083 1 NC_010723.1 putative lipoprotein 454083 6318391 CLH_0451 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001919859.1 452959 D 508767 CDS YP_001919860.1 188588393 6318061 complement(454086..455207) 1 NC_010723.1 identified by match to protein family HMM PF00534; mannosyltransferase B 455207 6318061 CLH_0452 Clostridium botulinum E3 str. Alaska E43 mannosyltransferase B YP_001919860.1 454086 R 508767 CDS YP_001919861.1 188587640 6319831 455354..456370 1 NC_010723.1 identified by match to protein family HMM TIGR02906; CotS family spore coat protein 456370 6319831 CLH_0453 Clostridium botulinum E3 str. Alaska E43 CotS family spore coat protein YP_001919861.1 455354 D 508767 CDS YP_001919862.1 188588180 6319426 456345..457115 1 NC_010723.1 hypothetical protein 457115 6319426 CLH_0454 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919862.1 456345 D 508767 CDS YP_001919863.1 188590738 6319358 457204..458256 1 NC_010723.1 identified by match to protein family HMM TIGR02906; CotS family spore coat protein 458256 6319358 CLH_0455 Clostridium botulinum E3 str. Alaska E43 CotS family spore coat protein YP_001919863.1 457204 D 508767 CDS YP_001919864.1 188589394 6319271 complement(458450..459592) 1 NC_010723.1 identified by match to protein family HMM PF00534; mannosyltransferase B 459592 6319271 CLH_0456 Clostridium botulinum E3 str. Alaska E43 mannosyltransferase B YP_001919864.1 458450 R 508767 CDS YP_001919865.1 188588887 6318653 459702..460703 1 NC_010723.1 identified by match to protein family HMM TIGR02906; spore coat protein CotS 460703 6318653 CLH_0457 Clostridium botulinum E3 str. Alaska E43 spore coat protein CotS YP_001919865.1 459702 D 508767 CDS YP_001919866.1 188590052 6320323 461028..461891 1 NC_010723.1 identified by match to protein family HMM PF05582; match to protein family HMM TIGR02855; sporulation peptidase YabG 461891 6320323 CLH_0458 Clostridium botulinum E3 str. Alaska E43 sporulation peptidase YabG YP_001919866.1 461028 D 508767 CDS YP_001919867.1 188589427 6317582 462079..462321 1 NC_010723.1 identified by match to protein family HMM PF06257; hypothetical protein 462321 6317582 CLH_0459 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919867.1 462079 D 508767 CDS YP_001919868.1 188589833 6317696 462735..464297 1 NC_010723.1 identified by match to protein family HMM PF01476; LysM domain containing membrane protein 464297 6317696 CLH_0460 Clostridium botulinum E3 str. Alaska E43 LysM domain containing membrane protein YP_001919868.1 462735 D 508767 CDS YP_001919869.1 188587589 6320019 464457..465302 1 NC_010723.1 identified by match to protein family HMM PF03575; match to protein family HMM TIGR02069; cyanophycinase 465302 6320019 CLH_0461 Clostridium botulinum E3 str. Alaska E43 cyanophycinase YP_001919869.1 464457 D 508767 CDS YP_001919870.1 188590785 6318188 465274..467892 1 NC_010723.1 catalyze the formation of cyanophycin which may act to store excess nitrogen; cyanophycin synthetase 467892 cphA 6318188 cphA Clostridium botulinum E3 str. Alaska E43 cyanophycin synthetase YP_001919870.1 465274 D 508767 CDS YP_001919871.1 188589866 6319065 468072..468914 1 NC_010723.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 468914 ipk 6319065 ipk Clostridium botulinum E3 str. Alaska E43 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001919871.1 468072 D 508767 CDS YP_001919872.1 188588954 6320538 468976..469602 1 NC_010723.1 identified by match to protein family HMM PF09551; match to protein family HMM TIGR02837; stage II sporulation protein R 469602 spoIIR 6320538 spoIIR Clostridium botulinum E3 str. Alaska E43 stage II sporulation protein R YP_001919872.1 468976 D 508767 CDS YP_001919873.1 188589825 6320531 469640..470632 1 NC_010723.1 identified by match to protein family HMM PF02568; match to protein family HMM PF05670; argininosuccinate synthase 470632 6320531 CLH_0465 Clostridium botulinum E3 str. Alaska E43 argininosuccinate synthase YP_001919873.1 469640 D 508767 CDS YP_001919874.1 188589550 6320425 470702..471124 1 NC_010723.1 identified by match to protein family HMM PF09148; hypothetical protein 471124 6320425 CLH_0466 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919874.1 470702 D 508767 CDS YP_001919875.1 188587984 6320216 471359..471658 1 NC_010723.1 hypothetical protein 471658 6320216 CLH_0467 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919875.1 471359 D 508767 CDS YP_001919876.1 188587693 6319013 471842..473443 1 NC_010723.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 473443 pyrG 6319013 pyrG Clostridium botulinum E3 str. Alaska E43 CTP synthetase YP_001919876.1 471842 D 508767 CDS YP_001919877.1 188590255 6318749 473822..475462 1 NC_010723.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 475462 rho 6318749 rho Clostridium botulinum E3 str. Alaska E43 transcription termination factor Rho YP_001919877.1 473822 D 508767 CDS YP_001919878.1 188589806 6318069 complement(475511..476617) 1 NC_010723.1 identified by match to protein family HMM PF04101; match to protein family HMM PF06925; putative monogalactosyldiacylglycerol synthase 476617 6318069 CLH_0470 Clostridium botulinum E3 str. Alaska E43 putative monogalactosyldiacylglycerol synthase YP_001919878.1 475511 R 508767 CDS YP_001919879.1 188589119 6320115 complement(476759..476968) 1 NC_010723.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 476968 rpmE 6320115 rpmE Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L31 YP_001919879.1 476759 R 508767 CDS YP_001919880.1 188587968 6319738 477146..477733 1 NC_010723.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 477733 tdk 6319738 tdk Clostridium botulinum E3 str. Alaska E43 thymidine kinase YP_001919880.1 477146 D 508767 CDS YP_001919881.1 188590603 6317662 477763..478671 1 NC_010723.1 identified by match to protein family HMM PF07136; HemK family modification methylase 478671 6317662 CLH_0473 Clostridium botulinum E3 str. Alaska E43 HemK family modification methylase YP_001919881.1 477763 D 508767 CDS YP_001919882.1 188589649 6319314 478661..479527 1 NC_010723.1 identified by match to protein family HMM PF05175; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387; match to protein family HMM TIGR03534; protein-(glutamine-N5) methyltransferase 479527 hemK 6319314 hemK Clostridium botulinum E3 str. Alaska E43 protein-(glutamine-N5) methyltransferase YP_001919882.1 478661 D 508767 CDS YP_001919883.1 188590258 6320033 479796..480878 1 NC_010723.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 480878 prfA 6320033 prfA Clostridium botulinum E3 str. Alaska E43 peptide chain release factor 1 YP_001919883.1 479796 D 508767 CDS YP_001919884.1 188588111 6320068 480961..481548 1 NC_010723.1 hypothetical protein 481548 6320068 CLH_0476 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919884.1 480961 D 508767 CDS YP_001919885.1 188589112 6319181 481567..482616 1 NC_010723.1 identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 482616 6319181 CLH_0477 Clostridium botulinum E3 str. Alaska E43 Sua5/YciO/YrdC/YwlC family protein YP_001919885.1 481567 D 508767 CDS YP_001919886.1 188589882 6320560 482739..483188 1 NC_010723.1 identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120; ribose 5-phosphate isomerase B 483188 rpiB 6320560 rpiB Clostridium botulinum E3 str. Alaska E43 ribose 5-phosphate isomerase B YP_001919886.1 482739 D 508767 CDS YP_001919887.1 188589376 6317906 483234..483863 1 NC_010723.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 483863 upp 6317906 upp Clostridium botulinum E3 str. Alaska E43 uracil phosphoribosyltransferase YP_001919887.1 483234 D 508767 CDS YP_001919888.1 188590082 6318532 483973..484467 1 NC_010723.1 identified by match to protein family HMM PF00383; deoxycytidylate deaminase 484467 6318532 CLH_0480 Clostridium botulinum E3 str. Alaska E43 deoxycytidylate deaminase YP_001919888.1 483973 D 508767 CDS YP_001919889.1 188587905 6317747 484596..485744 1 NC_010723.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 485744 6317747 CLH_0481 Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylglucosamine 2-epimerase YP_001919889.1 484596 D 508767 CDS YP_001919890.1 188588921 6318395 485874..487055 1 NC_010723.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 487055 6318395 CLH_0482 Clostridium botulinum E3 str. Alaska E43 acetyl-CoA acetyltransferase YP_001919890.1 485874 D 508767 CDS YP_001919891.1 188588688 6318097 487935..488300 1 NC_010723.1 hypothetical protein 488300 6318097 CLH_0483 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919891.1 487935 D 508767 CDS YP_001919892.1 188589169 6318129 488302..488982 1 NC_010723.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 488982 atpB 6318129 atpB Clostridium botulinum E3 str. Alaska E43 F0F1 ATP synthase subunit A YP_001919892.1 488302 D 508767 CDS YP_001919893.1 188587983 6318153 489014..489229 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 489229 atpE 6318153 atpE Clostridium botulinum E3 str. Alaska E43 F0F1 ATP synthase subunit C YP_001919893.1 489014 D 508767 CDS YP_001919894.1 188589454 6319092 489280..489759 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel; F0F1 ATP synthase subunit B 489759 atpF 6319092 atpF Clostridium botulinum E3 str. Alaska E43 F0F1 ATP synthase subunit B YP_001919894.1 489280 D 508767 CDS YP_001919895.1 188590336 6317491 489762..490301 1 NC_010723.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 490301 atpH 6317491 atpH Clostridium botulinum E3 str. Alaska E43 F0F1 ATP synthase subunit delta YP_001919895.1 489762 D 508767 CDS YP_001919896.1 188587639 6318603 490312..491826 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 491826 atpA 6318603 atpA Clostridium botulinum E3 str. Alaska E43 F0F1 ATP synthase subunit alpha YP_001919896.1 490312 D 508767 CDS YP_001919897.1 188588467 6319425 491867..492718 1 NC_010723.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 492718 atpG 6319425 atpG Clostridium botulinum E3 str. Alaska E43 F0F1 ATP synthase subunit gamma YP_001919897.1 491867 D 508767 CDS YP_001919898.1 188589828 6318438 492734..494125 1 NC_010723.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 494125 atpD 6318438 atpD Clostridium botulinum E3 str. Alaska E43 F0F1 ATP synthase subunit beta YP_001919898.1 492734 D 508767 CDS YP_001919899.1 188590445 6317314 494139..494543 1 NC_010723.1 identified by match to protein family HMM PF00401; match to protein family HMM PF02823; match to protein family HMM TIGR01216; ATP synthase F1 subunit epsilon 494543 atpC 6317314 atpC Clostridium botulinum E3 str. Alaska E43 ATP synthase F1 subunit epsilon YP_001919899.1 494139 D 508767 CDS YP_001919900.1 188588279 6318434 494703..495341 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 495341 6318434 CLH_0492 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919900.1 494703 D 508767 CDS YP_001919901.1 188589402 6319813 495399..496661 1 NC_010723.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 496661 murA 6319813 murA Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001919901.1 495399 D 508767 CDS YP_001919902.1 188589692 6318961 496779..497816 1 NC_010723.1 identified by match to protein family HMM PF08486; match to protein family HMM TIGR02669; match to protein family HMM TIGR02870; stage II sporulation protein D 497816 spoIID 6318961 spoIID Clostridium botulinum E3 str. Alaska E43 stage II sporulation protein D YP_001919902.1 496779 D 508767 CDS YP_001919903.1 188588981 6319597 497975..498700 1 NC_010723.1 identified by match to protein family HMM PF01551; hypothetical protein 498700 6319597 CLH_0495 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919903.1 497975 D 508767 CDS YP_001919904.1 188589727 6319342 498791..499045 1 NC_010723.1 identified by match to protein family HMM TIGR02844; sporulation transcriptional regulator spoiiid 499045 spoIIID 6319342 spoIIID Clostridium botulinum E3 str. Alaska E43 sporulation transcriptional regulator spoiiid YP_001919904.1 498791 D 508767 CDS YP_001919905.1 188587576 6318996 499125..500159 1 NC_010723.1 identified by match to protein family HMM PF02491; match to protein family HMM PF06723; match to protein family HMM TIGR00904; rod shape-determining protein Mbl 500159 6318996 CLH_0497 Clostridium botulinum E3 str. Alaska E43 rod shape-determining protein Mbl YP_001919905.1 499125 D 508767 CDS YP_001919906.1 188588272 6317916 complement(500203..500724) 1 NC_010723.1 identified by match to protein family HMM PF06866; match to protein family HMM TIGR02841; putative sporulation protein YyaC 500724 6317916 CLH_0498 Clostridium botulinum E3 str. Alaska E43 putative sporulation protein YyaC YP_001919906.1 500203 R 508767 CDS YP_001919907.1 188589579 6319828 500837..501247 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 501247 6319828 CLH_0499 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919907.1 500837 D 508767 CDS YP_001919908.1 188590301 6317676 502398..503573 1 NC_010723.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 503573 metK 6317676 metK Clostridium botulinum E3 str. Alaska E43 S-adenosylmethionine synthetase YP_001919908.1 502398 D 508767 CDS YP_001919909.1 188588110 6317955 504044..506263 1 NC_010723.1 identified by match to protein family HMM TIGR01448; helicase, RecD/TraA family 506263 6317955 CLH_0508 Clostridium botulinum E3 str. Alaska E43 helicase, RecD/TraA family YP_001919909.1 504044 D 508767 CDS YP_001919910.1 188589003 6319317 506298..507311 1 NC_010723.1 hypothetical protein 507311 6319317 CLH_0509 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919910.1 506298 D 508767 CDS YP_001919911.1 188589495 6319868 507287..507940 1 NC_010723.1 competence protein F 507940 6319868 CLH_0510 Clostridium botulinum E3 str. Alaska E43 competence protein F YP_001919911.1 507287 D 508767 CDS YP_001919912.1 188590439 6318724 508336..508869 1 NC_010723.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; 30S ribosomal protein S30AE family 508869 6318724 CLH_0511 Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S30AE family YP_001919912.1 508336 D 508767 CDS YP_001919913.1 188589340 6318199 509202..511712 1 NC_010723.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 511712 secA 6318199 secA Clostridium botulinum E3 str. Alaska E43 preprotein translocase subunit SecA YP_001919913.1 509202 D 508767 CDS YP_001919914.1 188590272 6317816 511883..512002 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 512002 6317816 CLH_0513 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919914.1 511883 D 508767 CDS YP_001919915.1 188590075 6320344 511989..513023 1 NC_010723.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA; peptide chain release factor 2 513023 prfB 6320344 prfB Clostridium botulinum E3 str. Alaska E43 peptide chain release factor 2 YP_001919915.1 511989 D 508767 CDS YP_001919916.1 188587723 6317593 complement(513214..514596) 1 NC_010723.1 identified by match to protein family HMM PF04389; aminopeptidase 514596 6317593 CLH_0515 Clostridium botulinum E3 str. Alaska E43 aminopeptidase YP_001919916.1 513214 R 508767 CDS YP_001919917.1 188589039 6318289 514797..515141 1 NC_010723.1 hypothetical protein 515141 6318289 CLH_0516 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919917.1 514797 D 508767 CDS YP_001919918.1 188589760 6318970 complement(515201..515533) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 515533 6318970 CLH_0517 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919918.1 515201 R 508767 CDS YP_001919919.1 188589637 6319130 515869..518046 1 NC_010723.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371; protein tex 518046 6319130 CLH_0518 Clostridium botulinum E3 str. Alaska E43 protein tex YP_001919919.1 515869 D 508767 CDS YP_001919920.1 188587910 6320098 518275..519225 1 NC_010723.1 identified by match to protein family HMM PF00892; exported membrane protein 519225 6320098 CLH_0519 Clostridium botulinum E3 str. Alaska E43 exported membrane protein YP_001919920.1 518275 D 508767 CDS YP_001919921.1 188588592 6317423 519413..520099 1 NC_010723.1 hypothetical protein 520099 6317423 CLH_0520 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919921.1 519413 D 508767 CDS YP_001919922.1 188589310 6318614 520124..521197 1 NC_010723.1 hypothetical protein 521197 6318614 CLH_0521 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919922.1 520124 D 508767 CDS YP_001919923.1 188590005 6317458 521913..522503 1 NC_010723.1 riboflavin transporter 522503 6317458 CLH_0522 Clostridium botulinum E3 str. Alaska E43 riboflavin transporter YP_001919923.1 521913 D 508767 CDS YP_001919924.1 188590690 6318834 complement(522538..522993) 1 NC_010723.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 522993 rimI 6318834 rimI Clostridium botulinum E3 str. Alaska E43 ribosomal-protein-alanine acetyltransferase YP_001919924.1 522538 R 508767 CDS YP_001919925.1 188587586 6319119 complement(522977..523693) 1 NC_010723.1 identified by match to protein family HMM PF00814; glycoprotease family protein 523693 6319119 CLH_0524 Clostridium botulinum E3 str. Alaska E43 glycoprotease family protein YP_001919925.1 522977 R 508767 CDS YP_001919926.1 188590370 6318196 complement(523690..524151) 1 NC_010723.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 524151 6318196 CLH_0525 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919926.1 523690 R 508767 CDS YP_001919927.1 188589464 6318224 524476..525342 1 NC_010723.1 identified by match to protein family HMM PF01297; putative ABC transporter substrate-binding lipoprotein 525342 6318224 CLH_0526 Clostridium botulinum E3 str. Alaska E43 putative ABC transporter substrate-binding lipoprotein YP_001919927.1 524476 D 508767 CDS YP_001919928.1 188588296 6320271 complement(526294..527361) 1 NC_010723.1 identified by match to protein family HMM PF03060; oxidoreductase, 2-nitropropane dioxygenase family 527361 6320271 CLH_0530 Clostridium botulinum E3 str. Alaska E43 oxidoreductase, 2-nitropropane dioxygenase family YP_001919928.1 526294 R 508767 CDS YP_001919929.1 188590692 6319909 527636..527821 1 NC_010723.1 identified by match to protein family HMM PF00269; hypothetical protein 527821 6319909 CLH_0531 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919929.1 527636 D 508767 CDS YP_001919930.1 188588460 6319121 528069..529265 1 NC_010723.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 529265 6319121 CLH_0532 Clostridium botulinum E3 str. Alaska E43 Ser/Thr protein phosphatase family protein YP_001919930.1 528069 D 508767 CDS YP_001919931.1 188587613 6319548 529621..531993 1 NC_010723.1 hypothetical protein 531993 6319548 CLH_0533 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919931.1 529621 D 508767 CDS YP_001919932.1 188588571 6319452 532079..532981 1 NC_010723.1 identified by match to protein family HMM PF01297; ABC transporter substrate-binding protein 532981 6319452 CLH_0534 Clostridium botulinum E3 str. Alaska E43 ABC transporter substrate-binding protein YP_001919932.1 532079 D 508767 CDS YP_001919933.1 188587889 6320318 533314..535107 1 NC_010723.1 identified by match to protein family HMM PF00488; MutS domain-containing protein 535107 6320318 CLH_0535 Clostridium botulinum E3 str. Alaska E43 MutS domain-containing protein YP_001919933.1 533314 D 508767 CDS YP_001919934.1 188590221 6317348 535225..536136 1 NC_010723.1 identified by match to protein family HMM PF00929; exonuclease family protein 536136 6317348 CLH_0536 Clostridium botulinum E3 str. Alaska E43 exonuclease family protein YP_001919934.1 535225 D 508767 CDS YP_001919935.1 188589400 6320453 536225..536662 1 NC_010723.1 identified by match to protein family HMM PF00571; hypothetical protein 536662 6320453 CLH_0537 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919935.1 536225 D 508767 CDS YP_001919936.1 188588462 6318637 complement(536724..537380) 1 NC_010723.1 hypothetical protein 537380 6318637 CLH_0538 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919936.1 536724 R 508767 CDS YP_001919937.1 188588349 6319550 complement(537391..538044) 1 NC_010723.1 identified by match to protein family HMM PF04012; phage shock protein A 538044 6319550 CLH_0539 Clostridium botulinum E3 str. Alaska E43 phage shock protein A YP_001919937.1 537391 R 508767 CDS YP_001919938.1 188590131 6318167 complement(538079..538840) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 538840 6318167 CLH_0540 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919938.1 538079 R 508767 CDS YP_001919939.1 188589736 6317342 539329..540465 1 NC_010723.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 540465 rpsA 6317342 rpsA Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S1 YP_001919939.1 539329 D 508767 CDS YP_001919940.1 188588791 6319694 complement(540809..542227) 1 NC_010723.1 identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; pyruvate kinase 542227 pyk 6319694 pyk Clostridium botulinum E3 str. Alaska E43 pyruvate kinase YP_001919940.1 540809 R 508767 CDS YP_001919941.1 188588666 6319175 542430..543884 1 NC_010723.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase 543884 6319175 CLH_0543 Clostridium botulinum E3 str. Alaska E43 aminoacyl-histidine dipeptidase YP_001919941.1 542430 D 508767 CDS YP_001919942.1 188588896 6319247 544201..544713 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 544713 6319247 CLH_0544 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001919942.1 544201 D 508767 CDS YP_001919943.1 188587969 6319366 544837..545493 1 NC_010723.1 identified by match to protein family HMM PF05036; hypothetical protein 545493 6319366 CLH_0545 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919943.1 544837 D 508767 CDS YP_001919944.1 188590062 6317663 545730..546296 1 NC_010723.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 546296 maf 6317663 maf Clostridium botulinum E3 str. Alaska E43 Maf-like protein YP_001919944.1 545730 D 508767 CDS YP_001919945.1 188589437 6320432 546341..547030 1 NC_010723.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 547030 radC 6320432 radC Clostridium botulinum E3 str. Alaska E43 DNA repair protein RadC YP_001919945.1 546341 D 508767 CDS YP_001919946.1 188589044 6317834 547049..548149 1 NC_010723.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 548149 6317834 CLH_0548 Clostridium botulinum E3 str. Alaska E43 rod shape-determining protein MreB YP_001919946.1 547049 D 508767 CDS YP_001919947.1 188588318 6319804 548153..548998 1 NC_010723.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 548998 mreC 6319804 mreC Clostridium botulinum E3 str. Alaska E43 rod shape-determining protein MreC YP_001919947.1 548153 D 508767 CDS YP_001919948.1 188587837 6319947 549009..549500 1 NC_010723.1 identified by match to protein family HMM TIGR03426; rod shape-determining protein MreD 549500 mreD 6319947 mreD Clostridium botulinum E3 str. Alaska E43 rod shape-determining protein MreD YP_001919948.1 549009 D 508767 CDS YP_001919949.1 188590189 6318817 549497..552412 1 NC_010723.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding Protein dimerisation domain family 552412 6318817 CLH_0551 Clostridium botulinum E3 str. Alaska E43 penicillin-binding Protein dimerisation domain family YP_001919949.1 549497 D 508767 CDS YP_001919950.1 188589762 6317786 552784..553431 1 NC_010723.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 553431 minC 6317786 minC Clostridium botulinum E3 str. Alaska E43 septum formation inhibitor YP_001919950.1 552784 D 508767 CDS YP_001919951.1 188588595 6319132 553450..554247 1 NC_010723.1 identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968; septum site-determining protein MinD 554247 minD 6319132 minD Clostridium botulinum E3 str. Alaska E43 septum site-determining protein MinD YP_001919951.1 553450 D 508767 CDS YP_001919952.1 188589476 6318635 554260..554526 1 NC_010723.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 554526 minE 6318635 minE Clostridium botulinum E3 str. Alaska E43 cell division topological specificity factor MinE YP_001919952.1 554260 D 508767 CDS YP_001919953.1 188589784 6317280 554653..555786 1 NC_010723.1 identified by match to protein family HMM PF01098; stage V sporulation protein E 555786 6317280 CLH_0555 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein E YP_001919953.1 554653 D 508767 CDS YP_001919954.1 188589606 6318281 555831..556190 1 NC_010723.1 identified by match to protein family HMM PF02142; match to protein family HMM TIGR00160; methylglyoxal synthase 556190 mgsA 6318281 mgsA Clostridium botulinum E3 str. Alaska E43 methylglyoxal synthase YP_001919954.1 555831 D 508767 CDS YP_001919955.1 188590558 6319001 556545..557342 1 NC_010723.1 identified by match to protein family HMM PF01551; putative cell wall endopeptidase, family M23/M37 557342 6319001 CLH_0557 Clostridium botulinum E3 str. Alaska E43 putative cell wall endopeptidase, family M23/M37 YP_001919955.1 556545 D 508767 CDS YP_001919956.1 188588184 6318505 557371..558246 1 NC_010723.1 identified by match to protein family HMM PF02163; sterol-regulatory element binding protein 558246 6318505 CLH_0558 Clostridium botulinum E3 str. Alaska E43 sterol-regulatory element binding protein YP_001919956.1 557371 D 508767 CDS YP_001919957.1 188588962 6319320 558456..560309 1 NC_010723.1 identified by match to protein family HMM PF04055; radical SAM domain protein 560309 6319320 CLH_0559 Clostridium botulinum E3 str. Alaska E43 radical SAM domain protein YP_001919957.1 558456 D 508767 CDS YP_001919958.1 188589122 6317520 560293..561006 1 NC_010723.1 hypothetical protein 561006 6317520 CLH_0560 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919958.1 560293 D 508767 CDS YP_001919959.1 188589242 6318285 561086..562534 1 NC_010723.1 identified by match to protein family HMM PF00575; match to protein family HMM TIGR00757; ribonuclease, Rne/Rng family 562534 6318285 CLH_0561 Clostridium botulinum E3 str. Alaska E43 ribonuclease, Rne/Rng family YP_001919959.1 561086 D 508767 CDS YP_001919960.1 188590270 6318252 562729..563040 1 NC_010723.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 563040 rplU 6318252 rplU Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L21 YP_001919960.1 562729 D 508767 CDS YP_001919961.1 188587689 6320342 563045..563431 1 NC_010723.1 identified by match to protein family HMM PF04327; hypothetical protein 563431 6320342 CLH_0563 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919961.1 563045 D 508767 CDS YP_001919962.1 188589658 6318238 563436..563735 1 NC_010723.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 563735 rpmA 6318238 rpmA Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L27 YP_001919962.1 563436 D 508767 CDS YP_001919963.1 188589146 6320109 564232..565518 1 NC_010723.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 565518 obgE 6320109 obgE Clostridium botulinum E3 str. Alaska E43 GTPase ObgE YP_001919963.1 564232 D 508767 CDS YP_001919964.1 188588103 6318854 565540..565836 1 NC_010723.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253; hypothetical protein 565836 6318854 CLH_0566 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919964.1 565540 D 508767 CDS YP_001919965.1 188590274 6317971 566217..566819 1 NC_010723.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 566819 nadD 6317971 nadD Clostridium botulinum E3 str. Alaska E43 nicotinic acid mononucleotide adenylyltransferase YP_001919965.1 566217 D 508767 CDS YP_001919966.1 188588634 6319310 566824..567399 1 NC_010723.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488; hypothetical protein 567399 6319310 CLH_0568 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919966.1 566824 D 508767 CDS YP_001919967.1 188590594 6317305 567475..568749 1 NC_010723.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; membrane-bound protein LytR 568749 6317305 CLH_0569 Clostridium botulinum E3 str. Alaska E43 membrane-bound protein LytR YP_001919967.1 567475 D 508767 CDS YP_001919968.1 188590633 6318014 568877..569773 1 NC_010723.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005; RluA family pseudouridine synthase 569773 6318014 CLH_0570 Clostridium botulinum E3 str. Alaska E43 RluA family pseudouridine synthase YP_001919968.1 568877 D 508767 CDS YP_001919969.1 188589932 6317873 complement(569793..571109) 1 NC_010723.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943; D-alanyl-D-alanine carboxypeptidase 571109 6317873 CLH_0571 Clostridium botulinum E3 str. Alaska E43 D-alanyl-D-alanine carboxypeptidase YP_001919969.1 569793 R 508767 CDS YP_001919970.1 188588252 6319490 571337..571951 1 NC_010723.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; ComE operon protein 1 571951 6319490 CLH_0572 Clostridium botulinum E3 str. Alaska E43 ComE operon protein 1 YP_001919970.1 571337 D 508767 CDS YP_001919971.1 188590428 6319715 572132..572836 1 NC_010723.1 putative lipoprotein 572836 6319715 CLH_0573 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001919971.1 572132 D 508767 CDS YP_001919972.1 188588972 6320526 572862..573242 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 573242 6320526 CLH_0574 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919972.1 572862 D 508767 CDS YP_001919973.1 188588342 6319583 573259..574611 1 NC_010723.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05175; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 574611 rumA 6319583 rumA Clostridium botulinum E3 str. Alaska E43 23S rRNA (uracil-5-)-methyltransferase RumA YP_001919973.1 573259 D 508767 CDS YP_001919974.1 188589578 6318376 575254..576267 1 NC_010723.1 identified by match to protein family HMM PF01497; putative iron compound ABC transporter periplasmic iron compound-binding protein 576267 6318376 CLH_0576 Clostridium botulinum E3 str. Alaska E43 putative iron compound ABC transporter periplasmic iron compound-binding protein YP_001919974.1 575254 D 508767 CDS YP_001919975.1 188588422 6317836 576290..577321 1 NC_010723.1 identified by match to protein family HMM PF01032; HmuU protein 577321 6317836 CLH_0577 Clostridium botulinum E3 str. Alaska E43 HmuU protein YP_001919975.1 576290 D 508767 CDS YP_001919976.1 188590410 6320014 577321..578076 1 NC_010723.1 identified by match to protein family HMM PF00005; iron chelate uptake ABC transporter, FeCT family, ATP-binding protein 578076 6320014 CLH_0578 Clostridium botulinum E3 str. Alaska E43 iron chelate uptake ABC transporter, FeCT family, ATP-binding protein YP_001919976.1 577321 D 508767 CDS YP_001919977.1 188589691 6317252 578321..580357 1 NC_010723.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF05223; penicillin-binding protein 3 580357 6317252 CLH_0579 Clostridium botulinum E3 str. Alaska E43 penicillin-binding protein 3 YP_001919977.1 578321 D 508767 CDS YP_001919978.1 188589952 6320074 580673..582316 1 NC_010723.1 identified by match to protein family HMM PF00515; match to protein family HMM PF00990; match to protein family HMM PF07719; match to protein family HMM TIGR00254; putative ggdef domain-containing protein 582316 6320074 CLH_0580 Clostridium botulinum E3 str. Alaska E43 putative ggdef domain-containing protein YP_001919978.1 580673 D 508767 CDS YP_001919979.1 188589157 6319566 582407..582571 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 582571 6319566 CLH_0581 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919979.1 582407 D 508767 CDS YP_001919980.1 188588242 6320190 582614..584356 1 NC_010723.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; sigma-54-dependent transcriptional regulator YgeV 584356 6320190 CLH_0582 Clostridium botulinum E3 str. Alaska E43 sigma-54-dependent transcriptional regulator YgeV YP_001919980.1 582614 D 508767 CDS YP_001919981.1 188590016 6319581 584737..585936 1 NC_010723.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 585936 6319581 CLH_0583 Clostridium botulinum E3 str. Alaska E43 peptidase YP_001919981.1 584737 D 508767 CDS YP_001919982.1 188587759 6318173 585987..587180 1 NC_010723.1 identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR03316; aspartate/ornithine carbamoyltransferase family protein 587180 ygeW 6318173 ygeW Clostridium botulinum E3 str. Alaska E43 aspartate/ornithine carbamoyltransferase family protein YP_001919982.1 585987 D 508767 CDS YP_001919983.1 188590311 6319972 587380..588312 1 NC_010723.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 588312 arcC 6319972 arcC Clostridium botulinum E3 str. Alaska E43 carbamate kinase YP_001919983.1 587380 D 508767 CDS YP_001919984.1 188590496 6317522 588441..589649 1 NC_010723.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 589649 dpaL 6317522 dpaL Clostridium botulinum E3 str. Alaska E43 diaminopropionate ammonia-lyase YP_001919984.1 588441 D 508767 CDS YP_001919985.1 188589786 6320175 589677..591008 1 NC_010723.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 591008 6320175 CLH_0587 Clostridium botulinum E3 str. Alaska E43 putative chlorohydrolase/aminohydrolase YP_001919985.1 589677 D 508767 CDS YP_001919986.1 188590451 6320473 591217..591366 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 591366 6320473 CLH_0588 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919986.1 591217 D 508767 CDS YP_001919987.1 188589730 6317741 591444..592805 1 NC_010723.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; hydroxydechloroatrazine ethylaminohydrolase 592805 6317741 CLH_0589 Clostridium botulinum E3 str. Alaska E43 hydroxydechloroatrazine ethylaminohydrolase YP_001919987.1 591444 D 508767 CDS YP_001919988.1 188588987 6318588 592844..593932 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01180; match to protein family HMM TIGR01037; dihydroorotate dehydrogenase family protein 593932 6318588 CLH_0590 Clostridium botulinum E3 str. Alaska E43 dihydroorotate dehydrogenase family protein YP_001919988.1 592844 D 508767 CDS YP_001919989.1 188588289 6318338 594070..594447 1 NC_010723.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; putative endoribonuclease L-PSP 594447 6318338 CLH_0591 Clostridium botulinum E3 str. Alaska E43 putative endoribonuclease L-PSP YP_001919989.1 594070 D 508767 CDS YP_001919990.1 188590303 6319783 594489..595043 1 NC_010723.1 hypothetical protein 595043 6319783 CLH_0592 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001919990.1 594489 D 508767 CDS YP_001919991.1 188590576 6318703 595103..596494 1 NC_010723.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 596494 hydA 6318703 hydA Clostridium botulinum E3 str. Alaska E43 phenylhydantoinase YP_001919991.1 595103 D 508767 CDS YP_001919992.1 188589529 6320182 597381..598778 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 598778 6320182 CLH_0594 Clostridium botulinum E3 str. Alaska E43 xanthine permease YP_001919992.1 597381 D 508767 CDS YP_001919993.1 188590126 6318114 598884..601445 1 NC_010723.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738; match to protein family HMM TIGR03311; selenium-dependent molybdenum hydroxylase 1 601445 6318114 CLH_0595 Clostridium botulinum E3 str. Alaska E43 selenium-dependent molybdenum hydroxylase 1 YP_001919993.1 598884 D 508767 CDS YP_001919994.1 188589366 6320443 complement(601521..601994) 1 NC_010723.1 identified by match to protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 601994 6320443 CLH_0596 Clostridium botulinum E3 str. Alaska E43 cytidine/deoxycytidylate deaminase family protein YP_001919994.1 601521 R 508767 CDS YP_001919995.1 188590121 6319264 602624..604915 1 NC_010723.1 putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 604915 6319264 CLH_0597 Clostridium botulinum E3 str. Alaska E43 xanthine dehydrogenase subunit XdhA YP_001919995.1 602624 D 508767 CDS YP_001919996.1 188588346 6317645 604933..605805 1 NC_010723.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 605805 6317645 CLH_0598 Clostridium botulinum E3 str. Alaska E43 xanthine dehydrogenase subunit XdhB YP_001919996.1 604933 D 508767 CDS YP_001919997.1 188588832 6320124 605807..606280 1 NC_010723.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; xanthine dehydrogenase family protein, iron-sulfur binding subunit 606280 6320124 CLH_0599 Clostridium botulinum E3 str. Alaska E43 xanthine dehydrogenase family protein, iron-sulfur binding subunit YP_001919997.1 605807 D 508767 CDS YP_001919998.1 188589776 6319330 606558..607943 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 607943 6319330 CLH_0600 Clostridium botulinum E3 str. Alaska E43 xanthine permease YP_001919998.1 606558 D 508767 CDS YP_001919999.1 188589461 6318090 608177..609208 1 NC_010723.1 identified by match to protein family HMM PF01497; iron ABC transporter substrate-binding protein 609208 6318090 CLH_0601 Clostridium botulinum E3 str. Alaska E43 iron ABC transporter substrate-binding protein YP_001919999.1 608177 D 508767 CDS YP_001920000.1 188590359 6317322 609205..610194 1 NC_010723.1 identified by match to protein family HMM PF01032; iron chelate uptake ABC transporter permease 610194 6317322 CLH_0602 Clostridium botulinum E3 str. Alaska E43 iron chelate uptake ABC transporter permease YP_001920000.1 609205 D 508767 CDS YP_001920001.1 188587944 6318595 610191..610970 1 NC_010723.1 identified by match to protein family HMM PF00005; putative iron ABC transporter ATP-binding protein 610970 6318595 CLH_0603 Clostridium botulinum E3 str. Alaska E43 putative iron ABC transporter ATP-binding protein YP_001920001.1 610191 D 508767 CDS YP_001920002.1 188588845 6320550 611043..611858 1 NC_010723.1 identified by match to protein family HMM TIGR03172; hypothetical protein 611858 6320550 CLH_0604 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920002.1 611043 D 508767 CDS YP_001920003.1 188588060 6318726 612002..612790 1 NC_010723.1 identified by match to protein family HMM TIGR03309; selenium-dependent molybdenum hydroxylase system protein, YqeB family 612790 6318726 CLH_0605 Clostridium botulinum E3 str. Alaska E43 selenium-dependent molybdenum hydroxylase system protein, YqeB family YP_001920003.1 612002 D 508767 CDS YP_001920004.1 188590542 6318470 612887..613507 1 NC_010723.1 identified by match to protein family HMM TIGR03527; selenium metabolism protein YedF 613507 6318470 CLH_0606 Clostridium botulinum E3 str. Alaska E43 selenium metabolism protein YedF YP_001920004.1 612887 D 508767 CDS YP_001920005.1 188589950 6318782 613640..614677 1 NC_010723.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00476; selenide, water dikinase 614677 selD 6318782 selD Clostridium botulinum E3 str. Alaska E43 selenide, water dikinase YP_001920005.1 613640 D 508767 CDS YP_001920006.1 188590673 6319696 614921..616072 1 NC_010723.1 identified by match to protein family HMM PF06050; 2-hydroxyacyl-CoA dehydratase subunit beta 616072 6319696 CLH_0608 Clostridium botulinum E3 str. Alaska E43 2-hydroxyacyl-CoA dehydratase subunit beta YP_001920006.1 614921 D 508767 CDS YP_001920007.1 188589974 6320176 616118..616876 1 NC_010723.1 identified by similarity to SP:P11568; match to protein family HMM PF01869; match to protein family HMM TIGR00241; 2-hydroxyglutaryl-CoA dehydratase 616876 hgdC 6320176 hgdC Clostridium botulinum E3 str. Alaska E43 2-hydroxyglutaryl-CoA dehydratase YP_001920007.1 616118 D 508767 CDS YP_001920008.1 188588365 6319351 616935..617534 1 NC_010723.1 molybdopterin-guanine dinucleotide biosynthesis protein A 617534 6319351 CLH_0610 Clostridium botulinum E3 str. Alaska E43 molybdopterin-guanine dinucleotide biosynthesis protein A YP_001920008.1 616935 D 508767 CDS YP_001920009.1 188587688 6319709 617531..618595 1 NC_010723.1 identified by match to protein family HMM PF02625; putative xanthine dehydrogenase accessory factor 618595 6319709 CLH_0611 Clostridium botulinum E3 str. Alaska E43 putative xanthine dehydrogenase accessory factor YP_001920009.1 617531 D 508767 CDS YP_001920010.1 188590273 6319203 618846..619658 1 NC_010723.1 identified by match to protein family HMM PF02361; match to protein family HMM TIGR02454; cobalt ABC transporter permease CbiQ 619658 cbiQ 6319203 cbiQ Clostridium botulinum E3 str. Alaska E43 cobalt ABC transporter permease CbiQ YP_001920010.1 618846 D 508767 CDS YP_001920011.1 188590453 6319309 619670..620503 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01166; cobalt import ATP-binding protein CbiO 620503 6319309 CLH_0613 Clostridium botulinum E3 str. Alaska E43 cobalt import ATP-binding protein CbiO YP_001920011.1 619670 D 508767 CDS YP_001920012.1 188588628 6317364 620930..621676 1 NC_010723.1 identified by match to protein family HMM PF01891; match to protein family HMM TIGR00123; cobalamin biosynthesis protein CbiM 621676 cbiM 6317364 cbiM Clostridium botulinum E3 str. Alaska E43 cobalamin biosynthesis protein CbiM YP_001920012.1 620930 D 508767 CDS YP_001920013.1 188589369 6318926 621679..621999 1 NC_010723.1 identified by match to protein family HMM PF02553; cobalt/cobalamin transport protein CbiN 621999 6318926 CLH_0615 Clostridium botulinum E3 str. Alaska E43 cobalt/cobalamin transport protein CbiN YP_001920013.1 621679 D 508767 CDS YP_001920014.1 188588545 6320223 622270..622383 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 622383 6320223 CLH_0616 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920014.1 622270 D 508767 CDS YP_001920015.1 188589564 6318943 622464..622625 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 622625 6318943 CLH_0617 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920015.1 622464 D 508767 CDS YP_001920016.1 188590776 6317477 622700..622834 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 622834 6317477 CLH_0618 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920016.1 622700 D 508767 CDS YP_001920017.1 188587708 6317951 complement(622928..623533) 1 NC_010723.1 identified by match to protein family HMM PF00440; TetR-family transcriptional regulator 623533 6317951 CLH_0619 Clostridium botulinum E3 str. Alaska E43 TetR-family transcriptional regulator YP_001920017.1 622928 R 508767 CDS YP_001920018.1 188588774 6317354 623802..624725 1 NC_010723.1 hypothetical protein 624725 6317354 CLH_0620 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920018.1 623802 D 508767 CDS YP_001920019.1 188589920 6318451 624804..626303 1 NC_010723.1 hypothetical protein 626303 6318451 CLH_0621 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920019.1 624804 D 508767 CDS YP_001920020.1 188589538 6320399 626306..627460 1 NC_010723.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF08030; putative oxidoreductase 627460 6320399 CLH_0622 Clostridium botulinum E3 str. Alaska E43 putative oxidoreductase YP_001920020.1 626306 D 508767 CDS YP_001920021.1 188590283 6319285 627582..628748 1 NC_010723.1 hypothetical protein 628748 6319285 CLH_0623 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920021.1 627582 D 508767 CDS YP_001920022.1 188588357 6318640 628951..630906 1 NC_010723.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; signal-transduction and transcriptional-control protein 630906 6318640 CLH_0624 Clostridium botulinum E3 str. Alaska E43 signal-transduction and transcriptional-control protein YP_001920022.1 628951 D 508767 CDS YP_001920023.1 188590686 6319637 631160..632233 1 NC_010723.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 632233 6319637 CLH_0625 Clostridium botulinum E3 str. Alaska E43 oxidoreductase, zinc-binding dehydrogenase family YP_001920023.1 631160 D 508767 CDS YP_001920024.1 188589933 6320328 632254..633141 1 NC_010723.1 identified by match to protein family HMM PF00175; ferredoxin-NADP(+) reductase subunit alpha 633141 6320328 CLH_0626 Clostridium botulinum E3 str. Alaska E43 ferredoxin-NADP(+) reductase subunit alpha YP_001920024.1 632254 D 508767 CDS YP_001920025.1 188588379 6319491 633144..634535 1 NC_010723.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 634535 gltA 6319491 gltA Clostridium botulinum E3 str. Alaska E43 putative oxidoreductase YP_001920025.1 633144 D 508767 CDS YP_001920026.1 188587630 6319760 634873..636582 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 636582 6319760 CLH_0628 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001920026.1 634873 D 508767 CDS YP_001920027.1 188590224 6319586 636788..637474 1 NC_010723.1 identified by match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 637474 6319586 CLH_0629 Clostridium botulinum E3 str. Alaska E43 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_001920027.1 636788 D 508767 CDS YP_001920028.1 188589487 6317291 637556..638263 1 NC_010723.1 identified by match to protein family HMM PF06912; hypothetical protein 638263 6317291 CLH_0630 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920028.1 637556 D 508767 CDS YP_001920029.1 188587964 6320574 638577..639092 1 NC_010723.1 identified by match to protein family HMM PF00583; GnaT-family acetyltransferase 639092 6320574 CLH_0631 Clostridium botulinum E3 str. Alaska E43 GnaT-family acetyltransferase YP_001920029.1 638577 D 508767 CDS YP_001920030.1 188590711 6317327 639295..640161 1 NC_010723.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 640161 6317327 CLH_0632 Clostridium botulinum E3 str. Alaska E43 short chain dehydrogenase/reductase family oxidoreductase YP_001920030.1 639295 D 508767 CDS YP_001920031.1 188589877 6318786 640463..641188 1 NC_010723.1 identified by match to protein family HMM PF00561; putative arylesterase 641188 6318786 CLH_0633 Clostridium botulinum E3 str. Alaska E43 putative arylesterase YP_001920031.1 640463 D 508767 CDS YP_001920032.1 188589288 6318592 641491..642477 1 NC_010723.1 identified by match to protein family HMM PF08541; match to protein family HMM PF08545; 3-oxoacyl-ACP synthase 642477 6318592 CLH_0634 Clostridium botulinum E3 str. Alaska E43 3-oxoacyl-ACP synthase YP_001920032.1 641491 D 508767 CDS YP_001920033.1 188588444 6320465 642603..643391 1 NC_010723.1 identified by match to protein family HMM PF01909; nucleotidyltransferase domain protein 643391 6320465 CLH_0635 Clostridium botulinum E3 str. Alaska E43 nucleotidyltransferase domain protein YP_001920033.1 642603 D 508767 CDS YP_001920034.1 188588265 6319742 complement(643460..643642) 1 NC_010723.1 hypothetical protein 643642 6319742 CLH_0636 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920034.1 643460 R 508767 CDS YP_001920035.1 188588246 6319838 complement(643754..644296) 1 NC_010723.1 hypothetical protein 644296 6319838 CLH_0637 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920035.1 643754 R 508767 CDS YP_001920036.1 188589219 6319544 644570..644947 1 NC_010723.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; putative endoribonuclease L-PSP 644947 6319544 CLH_0638 Clostridium botulinum E3 str. Alaska E43 putative endoribonuclease L-PSP YP_001920036.1 644570 D 508767 CDS YP_001920037.1 188588498 6317558 complement(645022..645777) 1 NC_010723.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; putative HTH-type transcriptional regulator YciT 645777 6317558 CLH_0639 Clostridium botulinum E3 str. Alaska E43 putative HTH-type transcriptional regulator YciT YP_001920037.1 645022 R 508767 CDS YP_001920038.1 188587925 6317515 complement(646215..646664) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 646664 6317515 CLH_0640 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920038.1 646215 R 508767 CDS YP_001920039.1 188587873 6318685 646842..647141 1 NC_010723.1 hypothetical protein 647141 6318685 CLH_0641 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920039.1 646842 D 508767 CDS YP_001920040.1 188590502 6317693 complement(647220..648032) 1 NC_010723.1 ABC transporter permease 648032 6317693 CLH_0642 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001920040.1 647220 R 508767 CDS YP_001920041.1 188589767 6319042 complement(648026..648730) 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 648730 6319042 CLH_0643 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001920041.1 648026 R 508767 CDS YP_001920042.1 188589533 6320087 complement(648730..649098) 1 NC_010723.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 649098 6320087 CLH_0644 Clostridium botulinum E3 str. Alaska E43 GntR family transcriptional regulator YP_001920042.1 648730 R 508767 CDS YP_001920043.1 188588481 6320302 649405..650865 1 NC_010723.1 identified by match to protein family HMM PF00015; putative methyl-accepting chemotaxis sensory transducer 650865 6320302 CLH_0645 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis sensory transducer YP_001920043.1 649405 D 508767 CDS YP_001920044.1 188589440 6317991 651168..652352 1 NC_010723.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04918; putative D-alanine transferase 652352 6317991 CLH_0646 Clostridium botulinum E3 str. Alaska E43 putative D-alanine transferase YP_001920044.1 651168 D 508767 CDS YP_001920045.1 188588126 6318308 652321..652461 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 652461 6318308 CLH_0647 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920045.1 652321 D 508767 CDS YP_001920046.1 188588853 6317845 652479..653993 1 NC_010723.1 identified by match to protein family HMM PF00501; putative D-alanine-activating enzyme 653993 6317845 CLH_0648 Clostridium botulinum E3 str. Alaska E43 putative D-alanine-activating enzyme YP_001920046.1 652479 D 508767 CDS YP_001920047.1 188588999 6318946 653993..655147 1 NC_010723.1 identified by match to protein family HMM PF03062; protein DltB 655147 6318946 CLH_0649 Clostridium botulinum E3 str. Alaska E43 protein DltB YP_001920047.1 653993 D 508767 CDS YP_001920048.1 188589702 6319699 655225..655452 1 NC_010723.1 identified by match to protein family HMM PF00550; match to protein family HMM TIGR01688; D-alanyl carrier protein 655452 dltC 6319699 dltC Clostridium botulinum E3 str. Alaska E43 D-alanyl carrier protein YP_001920048.1 655225 D 508767 CDS YP_001920049.1 188587832 6317602 complement(657550..658251) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 658251 6317602 CLH_0654 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920049.1 657550 R 508767 CDS YP_001920050.1 188589428 6317260 658647..660473 1 NC_010723.1 identified by match to protein family HMM PF03009; putative glycerophosphoryl diester phosphodiesterase 660473 6317260 CLH_0655 Clostridium botulinum E3 str. Alaska E43 putative glycerophosphoryl diester phosphodiesterase YP_001920050.1 658647 D 508767 CDS YP_001920051.1 188588909 6317697 complement(660681..661688) 1 NC_010723.1 identified by match to protein family HMM PF01408; putative oxidoreductase YgjR 661688 6317697 CLH_0656 Clostridium botulinum E3 str. Alaska E43 putative oxidoreductase YgjR YP_001920051.1 660681 R 508767 CDS YP_001920052.1 188588029 6317851 662033..663244 1 NC_010723.1 FliB family protein 663244 6317851 CLH_0657 Clostridium botulinum E3 str. Alaska E43 FliB family protein YP_001920052.1 662033 D 508767 CDS YP_001920053.1 188590771 6319212 complement(663577..664125) 1 NC_010723.1 hypothetical protein 664125 6319212 CLH_0658 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920053.1 663577 R 508767 CDS YP_001920054.1 188590281 6320071 664334..665956 1 NC_010723.1 putative lipoprotein 665956 6320071 CLH_0659 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001920054.1 664334 D 508767 CDS YP_001920055.1 188589090 6320187 666195..667238 1 NC_010723.1 identified by match to protein family HMM TIGR02910; sulfite reductase subunit A 667238 asrA 6320187 asrA Clostridium botulinum E3 str. Alaska E43 sulfite reductase subunit A YP_001920055.1 666195 D 508767 CDS YP_001920056.1 188588383 6318763 667239..668054 1 NC_010723.1 with AsrAC catalyzes the reduction of sulfite to hydrogen sulfide; anaerobic sulfite reductase subunit B 668054 asrB 6318763 asrB Clostridium botulinum E3 str. Alaska E43 anaerobic sulfite reductase subunit B YP_001920056.1 667239 D 508767 CDS YP_001920057.1 188587898 6319967 668068..669105 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01077; match to protein family HMM TIGR02912; sulfite reductase subunit C 669105 asrC 6319967 asrC Clostridium botulinum E3 str. Alaska E43 sulfite reductase subunit C YP_001920057.1 668068 D 508767 CDS YP_001920058.1 188589795 6318039 complement(669259..669936) 1 NC_010723.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; hypothetical protein 669936 6318039 CLH_0663 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920058.1 669259 R 508767 CDS YP_001920059.1 188589443 6320614 670055..671248 1 NC_010723.1 identified by match to protein family HMM PF07690; transporter 671248 6320614 CLH_0664 Clostridium botulinum E3 str. Alaska E43 transporter YP_001920059.1 670055 D 508767 CDS YP_001920060.1 188589446 6318759 complement(671535..672836) 1 NC_010723.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 672836 6318759 CLH_0665 Clostridium botulinum E3 str. Alaska E43 sodium:dicarboxylate symporter family protein YP_001920060.1 671535 R 508767 CDS YP_001920061.1 188589322 6319169 complement(673028..673915) 1 NC_010723.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR-family transcriptional regulator 673915 6319169 CLH_0666 Clostridium botulinum E3 str. Alaska E43 LysR-family transcriptional regulator YP_001920061.1 673028 R 508767 CDS YP_001920062.1 188590004 6317333 674102..674866 1 NC_010723.1 identified by match to protein family HMM PF01487; match to protein family HMM TIGR01093; 3-dehydroquinate dehydratase 674866 aroD 6317333 aroD Clostridium botulinum E3 str. Alaska E43 3-dehydroquinate dehydratase YP_001920062.1 674102 D 508767 CDS YP_001920063.1 188587948 6318833 675002..675871 1 NC_010723.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 675871 aroE 6318833 aroE Clostridium botulinum E3 str. Alaska E43 shikimate 5-dehydrogenase YP_001920063.1 675002 D 508767 CDS YP_001920064.1 188588639 6317254 675895..677118 1 NC_010723.1 identified by match to protein family HMM PF07690; inner membrane transport protein YdiN 677118 6317254 CLH_0669 Clostridium botulinum E3 str. Alaska E43 inner membrane transport protein YdiN YP_001920064.1 675895 D 508767 CDS YP_001920065.1 188590356 6320307 677359..679347 1 NC_010723.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00724; match to protein family HMM PF07992; NADH oxidase 679347 6320307 CLH_0670 Clostridium botulinum E3 str. Alaska E43 NADH oxidase YP_001920065.1 677359 D 508767 CDS YP_001920066.1 188587994 6317668 679612..680037 1 NC_010723.1 identified by match to protein family HMM PF00258; match to protein family HMM TIGR01753; flavodoxin 680037 6317668 CLH_0671 Clostridium botulinum E3 str. Alaska E43 flavodoxin YP_001920066.1 679612 D 508767 CDS YP_001920067.1 188588946 6317531 680048..680701 1 NC_010723.1 hypothetical protein 680701 6317531 CLH_0672 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920067.1 680048 D 508767 CDS YP_001920068.1 188589875 6318914 complement(680877..681383) 1 NC_010723.1 hypothetical protein 681383 6318914 CLH_0673 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920068.1 680877 R 508767 CDS YP_001920069.1 188589677 6318590 681856..682758 1 NC_010723.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; HD hydrolase superfamily protein 682758 6318590 CLH_0674 Clostridium botulinum E3 str. Alaska E43 HD hydrolase superfamily protein YP_001920069.1 681856 D 508767 CDS YP_001920070.1 188590598 6319350 682779..683375 1 NC_010723.1 hypothetical protein 683375 6319350 CLH_0675 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920070.1 682779 D 508767 CDS YP_001920071.1 188588008 6320330 683601..684434 1 NC_010723.1 identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587; AP endonuclease, family 2 684434 6320330 CLH_0676 Clostridium botulinum E3 str. Alaska E43 AP endonuclease, family 2 YP_001920071.1 683601 D 508767 CDS YP_001920072.1 188588729 6318898 684727..685944 1 NC_010723.1 identified by match to protein family HMM PF01266; putative oxidoreductase 685944 6318898 CLH_0677 Clostridium botulinum E3 str. Alaska E43 putative oxidoreductase YP_001920072.1 684727 D 508767 CDS YP_001920073.1 188589465 6320046 686320..687558 1 NC_010723.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 687558 6320046 CLH_0678 Clostridium botulinum E3 str. Alaska E43 ErfK/YbiS/YcfS/YnhG family protein YP_001920073.1 686320 D 508767 CDS YP_001920074.1 188590179 6320429 687849..688586 1 NC_010723.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR-family transcriptional regulator 688586 6320429 CLH_0679 Clostridium botulinum E3 str. Alaska E43 GntR-family transcriptional regulator YP_001920074.1 687849 D 508767 CDS YP_001920075.1 188587633 6318297 688610..689743 1 NC_010723.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 689743 nagA 6318297 nagA Clostridium botulinum E3 str. Alaska E43 N-acetylglucosamine-6-phosphate deacetylase YP_001920075.1 688610 D 508767 CDS YP_001920076.1 188589890 6319963 689854..690603 1 NC_010723.1 identified by match to protein family HMM PF01182; match to protein family HMM TIGR00502; glucosamine-6-phosphate isomerase 690603 nagB 6319963 nagB Clostridium botulinum E3 str. Alaska E43 glucosamine-6-phosphate isomerase YP_001920076.1 689854 D 508767 CDS YP_001920077.1 188588256 6318751 690650..692077 1 NC_010723.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01998; pts system, N-acetylglucosamine-specific iibc component 692077 nagE 6318751 nagE Clostridium botulinum E3 str. Alaska E43 pts system, N-acetylglucosamine-specific iibc component YP_001920077.1 690650 D 508767 CDS YP_001920078.1 188590461 6319886 692185..692859 1 NC_010723.1 identified by match to protein family HMM PF03932; copper homeostasis protein CutC 692859 6319886 CLH_0683 Clostridium botulinum E3 str. Alaska E43 copper homeostasis protein CutC YP_001920078.1 692185 D 508767 CDS YP_001920079.1 188589688 6320545 693192..693761 1 NC_010723.1 identified by match to protein family HMM PF02632; BioY family protein 693761 6320545 CLH_0684 Clostridium botulinum E3 str. Alaska E43 BioY family protein YP_001920079.1 693192 D 508767 CDS YP_001920080.1 188588102 6319955 693745..694701 1 NC_010723.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthase 694701 bioB 6319955 bioB Clostridium botulinum E3 str. Alaska E43 biotin synthase YP_001920080.1 693745 D 508767 CDS YP_001920081.1 188588784 6317970 694704..695387 1 NC_010723.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 695387 bioD 6317970 bioD Clostridium botulinum E3 str. Alaska E43 dithiobiotin synthetase YP_001920081.1 694704 D 508767 CDS YP_001920082.1 188588046 6318301 complement(695586..696413) 1 NC_010723.1 identified by match to protein family HMM PF00376; multidrug-efflux transporter 2 regulator 696413 6318301 CLH_0687 Clostridium botulinum E3 str. Alaska E43 multidrug-efflux transporter 2 regulator YP_001920082.1 695586 R 508767 CDS YP_001920083.1 188590704 6318041 696788..698515 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 698515 6318041 CLH_0688 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding/permease YP_001920083.1 696788 D 508767 CDS YP_001920084.1 188589953 6320204 698515..700296 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; lipid A export ATP-binding/permease protein MsbA 700296 6320204 CLH_0689 Clostridium botulinum E3 str. Alaska E43 lipid A export ATP-binding/permease protein MsbA YP_001920084.1 698515 D 508767 CDS YP_001920085.1 188588408 6319567 700360..700932 1 NC_010723.1 hypothetical protein 700932 6319567 CLH_0690 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920085.1 700360 D 508767 CDS YP_001920086.1 188587707 6319665 complement(701070..701363) 1 NC_010723.1 identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119; acetolactate synthase small subunit 701363 ilvN 6319665 ilvN Clostridium botulinum E3 str. Alaska E43 acetolactate synthase small subunit YP_001920086.1 701070 R 508767 CDS YP_001920087.1 188588035 6317353 complement(701356..703035) 1 NC_010723.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase large subunit 703035 ilvB 6317353 ilvB Clostridium botulinum E3 str. Alaska E43 acetolactate synthase large subunit YP_001920087.1 701356 R 508767 CDS YP_001920088.1 188589570 6318244 703579..704070 1 NC_010723.1 identified by match to protein family HMM PF02559; CarD family transcriptional regulator 704070 6318244 CLH_0693 Clostridium botulinum E3 str. Alaska E43 CarD family transcriptional regulator YP_001920088.1 703579 D 508767 CDS YP_001920089.1 188588269 6319644 704272..704427 1 NC_010723.1 hypothetical protein 704427 6319644 CLH_0694 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920089.1 704272 D 508767 CDS YP_001920090.1 188588967 6319837 complement(704534..705703) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 705703 6319837 CLH_0695 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001920090.1 704534 R 508767 CDS YP_001920091.1 188590139 6319824 complement(705721..711381) 1 NC_010723.1 identified by match to protein family HMM PF00041; match to protein family HMM PF00754; fibronectin type III domain protein 711381 6319824 CLH_0696 Clostridium botulinum E3 str. Alaska E43 fibronectin type III domain protein YP_001920091.1 705721 R 508767 CDS YP_001920092.1 188587573 6318848 711798..713255 1 NC_010723.1 identified by match to protein family HMM PF00015; putative methyl-accepting chemotaxis sensory transducer 713255 6318848 CLH_0697 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis sensory transducer YP_001920092.1 711798 D 508767 CDS YP_001920093.1 188587933 6320336 713716..715371 1 NC_010723.1 hypothetical protein 715371 6320336 CLH_0698 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920093.1 713716 D 508767 CDS YP_001920094.1 188588664 6317453 715983..717323 1 NC_010723.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 717323 brnQ 6317453 brnQ Clostridium botulinum E3 str. Alaska E43 branched-chain amino acid transport system II carrier protein YP_001920094.1 715983 D 508767 CDS YP_001920095.1 188589696 6319245 717532..718212 1 NC_010723.1 identified by match to protein family HMM PF00027; camp-binding domain 718212 6319245 CLH_0700 Clostridium botulinum E3 str. Alaska E43 camp-binding domain YP_001920095.1 717532 D 508767 CDS YP_001920096.1 188590414 6319675 complement(718431..719210) 1 NC_010723.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; deoxyribose operon repressor 719210 6319675 CLH_0701 Clostridium botulinum E3 str. Alaska E43 deoxyribose operon repressor YP_001920096.1 718431 R 508767 CDS YP_001920097.1 188589303 6318556 719505..720170 1 NC_010723.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 720170 deoC 6318556 deoC Clostridium botulinum E3 str. Alaska E43 deoxyribose-phosphate aldolase YP_001920097.1 719505 D 508767 CDS YP_001920098.1 188590378 6317275 720480..721781 1 NC_010723.1 identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831; match to protein family HMM TIGR02644; pyrimidine-nucleoside phosphorylase 721781 6317275 CLH_0703 Clostridium botulinum E3 str. Alaska E43 pyrimidine-nucleoside phosphorylase YP_001920098.1 720480 D 508767 CDS YP_001920099.1 188587569 6318054 722208..723851 1 NC_010723.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 723851 hcp 6318054 hcp Clostridium botulinum E3 str. Alaska E43 hydroxylamine reductase YP_001920099.1 722208 D 508767 CDS YP_001920100.1 188588913 6318123 723992..724771 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 724771 6318123 CLH_0705 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920100.1 723992 D 508767 CDS YP_001920101.1 188588645 6317897 724975..725658 1 NC_010723.1 identified by match to protein family HMM PF02588; hypothetical protein 725658 6317897 CLH_0706 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920101.1 724975 D 508767 CDS YP_001920102.1 188590425 6319055 725912..726472 1 NC_010723.1 identified by match to protein family HMM PF04647; accessory gene regulator B superfamily 726472 6319055 CLH_0707 Clostridium botulinum E3 str. Alaska E43 accessory gene regulator B superfamily YP_001920102.1 725912 D 508767 CDS YP_001920103.1 188590069 6320042 726518..726646 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 726646 6320042 CLH_0708 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920103.1 726518 D 508767 CDS YP_001920104.1 188587724 6317711 726674..727930 1 NC_010723.1 identified by match to protein family HMM PF02518; putative sensor histidine kinase 727930 6317711 CLH_0709 Clostridium botulinum E3 str. Alaska E43 putative sensor histidine kinase YP_001920104.1 726674 D 508767 CDS YP_001920105.1 188589865 6319767 728034..729263 1 NC_010723.1 two-component sensor histidine kinase 729263 6319767 CLH_0710 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001920105.1 728034 D 508767 CDS YP_001920106.1 188590760 6320537 complement(729307..729423) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 729423 6320537 CLH_0711 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920106.1 729307 R 508767 CDS YP_001920107.1 188587981 6318179 729458..730420 1 NC_010723.1 identified by match to protein family HMM PF06803; hypothetical protein 730420 6318179 CLH_0712 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920107.1 729458 D 508767 CDS YP_001920108.1 188588924 6318890 730456..731409 1 NC_010723.1 ribonuclease HI 731409 6318890 CLH_0713 Clostridium botulinum E3 str. Alaska E43 ribonuclease HI YP_001920108.1 730456 D 508767 CDS YP_001920109.1 188588578 6320064 731503..731679 1 NC_010723.1 hypothetical protein 731679 6320064 CLH_0714 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920109.1 731503 D 508767 CDS YP_001920110.1 188588525 6320593 731958..733256 1 NC_010723.1 identified by match to protein family HMM PF00515; match to protein family HMM PF01381; helix-turn-helix domain-containing protein 733256 6320593 CLH_0715 Clostridium botulinum E3 str. Alaska E43 helix-turn-helix domain-containing protein YP_001920110.1 731958 D 508767 CDS YP_001920111.1 188587608 6318931 733306..734571 1 NC_010723.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; tetratricopeptide repeat protein 734571 6318931 CLH_0716 Clostridium botulinum E3 str. Alaska E43 tetratricopeptide repeat protein YP_001920111.1 733306 D 508767 CDS YP_001920112.1 188588200 6319555 734784..735317 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 735317 6319555 CLH_0717 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920112.1 734784 D 508767 CDS YP_001920113.1 188589723 6319521 735468..738071 1 NC_010723.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346; ATP-dependent chaperone ClpB 738071 clpB 6319521 clpB Clostridium botulinum E3 str. Alaska E43 ATP-dependent chaperone ClpB YP_001920113.1 735468 D 508767 CDS YP_001920114.1 188588790 6318209 complement(738456..738638) 1 NC_010723.1 identified by match to protein family HMM PF00269; hypothetical protein 738638 6318209 CLH_0719 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920114.1 738456 R 508767 CDS YP_001920115.1 188587893 6318349 complement(738822..739790) 1 NC_010723.1 identified by match to protein family HMM PF03576; peptidase, T4 family 739790 6318349 CLH_0720 Clostridium botulinum E3 str. Alaska E43 peptidase, T4 family YP_001920115.1 738822 R 508767 CDS YP_001920116.1 188590241 6317359 complement(739969..740565) 1 NC_010723.1 membrane protein 740565 6317359 CLH_0721 Clostridium botulinum E3 str. Alaska E43 membrane protein YP_001920116.1 739969 R 508767 CDS YP_001920117.1 188588612 6318965 740971..741837 1 NC_010723.1 identified by match to protein family HMM PF01171; PP-loop family protein 741837 6318965 CLH_0722 Clostridium botulinum E3 str. Alaska E43 PP-loop family protein YP_001920117.1 740971 D 508767 CDS YP_001920118.1 188587746 6318036 741971..742168 1 NC_010723.1 hypothetical protein 742168 6318036 CLH_0723 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920118.1 741971 D 508767 CDS YP_001920119.1 188590088 6319764 742358..744112 1 NC_010723.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase/phosphodiesterase domain-containing protein 744112 6319764 CLH_0724 Clostridium botulinum E3 str. Alaska E43 diguanylate cyclase/phosphodiesterase domain-containing protein YP_001920119.1 742358 D 508767 CDS YP_001920120.1 188589014 6317615 744566..745084 1 NC_010723.1 putative tryptophan transport protein 745084 6317615 CLH_0725 Clostridium botulinum E3 str. Alaska E43 putative tryptophan transport protein YP_001920120.1 744566 D 508767 CDS YP_001920121.1 188588354 6319003 complement(745172..745888) 1 NC_010723.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase domain-containing protein 745888 6319003 CLH_0726 Clostridium botulinum E3 str. Alaska E43 polysaccharide deacetylase domain-containing protein YP_001920121.1 745172 R 508767 CDS YP_001920122.1 188588956 6318893 746305..751491 1 NC_010723.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; ggdef domain protein 751491 6318893 CLH_0727 Clostridium botulinum E3 str. Alaska E43 ggdef domain protein YP_001920122.1 746305 D 508767 CDS YP_001920123.1 188588268 6319343 751618..752268 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 752268 6319343 CLH_0728 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920123.1 751618 D 508767 CDS YP_001920124.1 188590503 6319836 752409..752849 1 NC_010723.1 identified by match to protein family HMM PF00692; match to protein family HMM TIGR00576; deoxyuridine 5'-triphosphate nucleotidohydrolase 752849 dut 6319836 dut Clostridium botulinum E3 str. Alaska E43 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001920124.1 752409 D 508767 CDS YP_001920125.1 188589700 6317997 complement(753132..755057) 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 755057 6317997 CLH_0730 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001920125.1 753132 R 508767 CDS YP_001920126.1 188589414 6318578 755165..755779 1 NC_010723.1 identified by match to protein family HMM PF00440; transcriptional regulator, TetR family 755779 6318578 CLH_0731 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, TetR family YP_001920126.1 755165 D 508767 CDS YP_001920127.1 188588675 6317567 complement(755914..756534) 1 NC_010723.1 hypothetical protein 756534 6317567 CLH_0732 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920127.1 755914 R 508767 CDS YP_001920128.1 188587848 6317246 complement(756545..757081) 1 NC_010723.1 hypothetical protein 757081 6317246 CLH_0733 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920128.1 756545 R 508767 CDS YP_001920129.1 188590175 6320438 757250..758557 1 NC_010723.1 identified by match to protein family HMM PF00266; cysteine desulfurase 758557 6320438 CLH_0734 Clostridium botulinum E3 str. Alaska E43 cysteine desulfurase YP_001920129.1 757250 D 508767 CDS YP_001920130.1 188589815 6318642 complement(758686..759903) 1 NC_010723.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 759903 6318642 CLH_0735 Clostridium botulinum E3 str. Alaska E43 6-phosphofructokinase YP_001920130.1 758686 R 508767 CDS YP_001920131.1 188589053 6320027 760121..760672 1 NC_010723.1 identified by match to protein family HMM PF02659; integral membrane protein 760672 6320027 CLH_0736 Clostridium botulinum E3 str. Alaska E43 integral membrane protein YP_001920131.1 760121 D 508767 CDS YP_001920132.1 188587747 6320463 760735..761148 1 NC_010723.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 761148 6320463 CLH_0737 Clostridium botulinum E3 str. Alaska E43 Fur family transcriptional regulator YP_001920132.1 760735 D 508767 CDS YP_001920133.1 188590342 6318953 complement(761462..762256) 1 NC_010723.1 identified by match to protein family HMM PF00950; hydrophobic membrane protein ZurM 762256 6318953 CLH_0738 Clostridium botulinum E3 str. Alaska E43 hydrophobic membrane protein ZurM YP_001920133.1 761462 R 508767 CDS YP_001920134.1 188590344 6318907 complement(762289..762963) 1 NC_010723.1 identified by match to protein family HMM PF00005; zinc import ATP-binding protein ZnuC 762963 6318907 CLH_0739 Clostridium botulinum E3 str. Alaska E43 zinc import ATP-binding protein ZnuC YP_001920134.1 762289 R 508767 CDS YP_001920135.1 188589388 6318909 complement(763061..763483) 1 NC_010723.1 hypothetical protein 763483 6318909 CLH_0740 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920135.1 763061 R 508767 CDS YP_001920136.1 188588079 6318606 763892..764290 1 NC_010723.1 hypothetical protein 764290 6318606 CLH_0741 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920136.1 763892 D 508767 CDS YP_001920137.1 188590492 6320605 764336..766120 1 NC_010723.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F 766120 pepF 6320605 pepF Clostridium botulinum E3 str. Alaska E43 oligoendopeptidase F YP_001920137.1 764336 D 508767 CDS YP_001920138.1 188589117 6318849 766483..767448 1 NC_010723.1 identified by match to protein family HMM PF01694; rhomboid family protein 767448 6318849 CLH_0743 Clostridium botulinum E3 str. Alaska E43 rhomboid family protein YP_001920138.1 766483 D 508767 CDS YP_001920139.1 188587607 6318350 767484..768095 1 NC_010723.1 hypothetical protein 768095 6318350 CLH_0744 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920139.1 767484 D 508767 CDS YP_001920140.1 188590742 6319554 768269..769621 1 NC_010723.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 769621 gluD 6319554 gluD Clostridium botulinum E3 str. Alaska E43 glutamate dehydrogenase YP_001920140.1 768269 D 508767 CDS YP_001920141.1 188589775 6317966 770171..771601 1 NC_010723.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 771601 6317966 CLH_0746 Clostridium botulinum E3 str. Alaska E43 glycosyl transferase family protein YP_001920141.1 770171 D 508767 CDS YP_001920142.1 188588859 6318089 772015..773964 1 NC_010723.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 773964 6318089 CLH_0747 Clostridium botulinum E3 str. Alaska E43 DNA topoisomerase IV subunit B YP_001920142.1 772015 D 508767 CDS YP_001920143.1 188587953 6317421 773985..776894 1 NC_010723.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 776894 6317421 CLH_0748 Clostridium botulinum E3 str. Alaska E43 DNA topoisomerase IV subunit A YP_001920143.1 773985 D 508767 CDS YP_001920144.1 188590733 6317398 776913..777449 1 NC_010723.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; protein ThiJ 777449 6317398 CLH_0749 Clostridium botulinum E3 str. Alaska E43 protein ThiJ YP_001920144.1 776913 D 508767 CDS YP_001920145.1 188589880 6317868 777576..779342 1 NC_010723.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 779342 recJ 6317868 recJ Clostridium botulinum E3 str. Alaska E43 single-stranded-DNA-specific exonuclease RecJ YP_001920145.1 777576 D 508767 CDS YP_001920146.1 188588466 6319308 complement(779686..779874) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 779874 6319308 CLH_0751 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920146.1 779686 R 508767 CDS YP_001920147.1 188587582 6318437 complement(779904..781199) 1 NC_010723.1 identified by match to protein family HMM PF02550; 4-hydroxybutyrate CoA-transferase 781199 6318437 CLH_0752 Clostridium botulinum E3 str. Alaska E43 4-hydroxybutyrate CoA-transferase YP_001920147.1 779904 R 508767 CDS YP_001920148.1 188590319 6318009 complement(781690..781887) 1 NC_010723.1 identified by match to protein family HMM PF00269; hypothetical protein 781887 6318009 CLH_0753 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920148.1 781690 R 508767 CDS YP_001920149.1 188589438 6320498 782486..783562 1 NC_010723.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 783562 murG 6320498 murG Clostridium botulinum E3 str. Alaska E43 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001920149.1 782486 D 508767 CDS YP_001920150.1 188590631 6318306 783749..784186 1 NC_010723.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 784186 6318306 CLH_0755 Clostridium botulinum E3 str. Alaska E43 flavodoxin YP_001920150.1 783749 D 508767 CDS YP_001920151.1 188588130 6319250 784313..787813 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate:ferredoxin (flavodoxin) oxidoreductase 787813 nifJ 6319250 nifJ Clostridium botulinum E3 str. Alaska E43 pyruvate:ferredoxin (flavodoxin) oxidoreductase YP_001920151.1 784313 D 508767 CDS YP_001920152.1 188587540 6319161 788313..788672 1 NC_010723.1 hypothetical protein 788672 6319161 CLH_0757 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920152.1 788313 D 508767 CDS YP_001920153.1 188588420 6318649 788976..790169 1 NC_010723.1 identified by match to protein family HMM PF00155; aspartate aminotransferase 790169 6318649 CLH_0758 Clostridium botulinum E3 str. Alaska E43 aspartate aminotransferase YP_001920153.1 788976 D 508767 CDS YP_001920154.1 188589583 6319719 790396..791034 1 NC_010723.1 identified by match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; HAD-superfamily hydrolase 791034 6319719 CLH_0759 Clostridium botulinum E3 str. Alaska E43 HAD-superfamily hydrolase YP_001920154.1 790396 D 508767 CDS YP_001920155.1 188590268 6319406 791060..791863 1 NC_010723.1 identified by match to protein family HMM PF01063; hypothetical protein 791863 6319406 CLH_0760 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920155.1 791060 D 508767 CDS YP_001920156.1 188588058 6320377 791944..793890 1 NC_010723.1 identified by match to protein family HMM PF03961; hypothetical protein 793890 6320377 CLH_0761 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920156.1 791944 D 508767 CDS YP_001920157.1 188588793 6318372 793905..794354 1 NC_010723.1 identified by match to protein family HMM PF01584; chemotaxis protein CheW 794354 6318372 CLH_0762 Clostridium botulinum E3 str. Alaska E43 chemotaxis protein CheW YP_001920157.1 793905 D 508767 CDS YP_001920158.1 188588221 6319177 794363..794851 1 NC_010723.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors; chemoreceptor glutamine deamidase CheD 794851 6319177 CLH_0763 Clostridium botulinum E3 str. Alaska E43 chemoreceptor glutamine deamidase CheD YP_001920158.1 794363 D 508767 CDS YP_001920159.1 188588780 6319656 794865..795971 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01339; chemotaxis response regulator protein-glutamate methylesterase 795971 6319656 CLH_0764 Clostridium botulinum E3 str. Alaska E43 chemotaxis response regulator protein-glutamate methylesterase YP_001920159.1 794865 D 508767 CDS YP_001920160.1 188590238 6317640 795981..796748 1 NC_010723.1 identified by match to protein family HMM PF01739; match to protein family HMM PF03705; CheR methyltransferase, SAM binding domain 796748 cheR 6317640 cheR Clostridium botulinum E3 str. Alaska E43 CheR methyltransferase, SAM binding domain YP_001920160.1 795981 D 508767 CDS YP_001920161.1 188589240 6319030 796760..798784 1 NC_010723.1 identified by match to protein family HMM PF01584; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF02895; match to protein family HMM PF07194; chemotaxis protein CheA 798784 6319030 CLH_0766 Clostridium botulinum E3 str. Alaska E43 chemotaxis protein CheA YP_001920161.1 796760 D 508767 CDS YP_001920162.1 188587565 6318250 798808..799407 1 NC_010723.1 identified by match to protein family HMM PF04509; CheY-P phosphatase CheC 799407 6318250 CLH_0767 Clostridium botulinum E3 str. Alaska E43 CheY-P phosphatase CheC YP_001920162.1 798808 D 508767 CDS YP_001920163.1 188590317 6320274 799426..799785 1 NC_010723.1 identified by match to protein family HMM PF00072; chemotaxis protein CheY 799785 6320274 CLH_0768 Clostridium botulinum E3 str. Alaska E43 chemotaxis protein CheY YP_001920163.1 799426 D 508767 CDS YP_001920164.1 188589817 6319913 799810..800205 1 NC_010723.1 identified by match to protein family HMM PF01584; chemotaxis signal transduction protein CheW 800205 6319913 CLH_0769 Clostridium botulinum E3 str. Alaska E43 chemotaxis signal transduction protein CheW YP_001920164.1 799810 D 508767 CDS YP_001920165.1 188588470 6320101 800227..801222 1 NC_010723.1 identified by match to protein family HMM PF01052; match to protein family HMM PF02154; match to protein family HMM TIGR01397; flagellar motor switch protein FliM 801222 fliM 6320101 fliM Clostridium botulinum E3 str. Alaska E43 flagellar motor switch protein FliM YP_001920165.1 800227 D 508767 CDS YP_001920166.1 188589151 6319922 801215..802366 1 NC_010723.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 802366 fliN 6319922 fliN Clostridium botulinum E3 str. Alaska E43 flagellar motor switch protein YP_001920166.1 801215 D 508767 CDS YP_001920167.1 188588160 6319027 802725..803003 1 NC_010723.1 identified by match to protein family HMM PF04316; negative regulator of flagellin synthesis 803003 6319027 CLH_0772 Clostridium botulinum E3 str. Alaska E43 negative regulator of flagellin synthesis YP_001920167.1 802725 D 508767 CDS YP_001920168.1 188590543 6318465 803007..803417 1 NC_010723.1 hypothetical protein 803417 6318465 CLH_0773 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920168.1 803007 D 508767 CDS YP_001920169.1 188589591 6318783 803509..805323 1 NC_010723.1 identified by match to protein family HMM PF00460; match to protein family HMM PF06429; match to protein family HMM TIGR02492; flagellar hook-associated protein FlgK 805323 flgK 6318783 flgK Clostridium botulinum E3 str. Alaska E43 flagellar hook-associated protein FlgK YP_001920169.1 803509 D 508767 CDS YP_001920170.1 188590093 6319765 805369..806577 1 NC_010723.1 identified by match to protein family HMM PF00669; match to protein family HMM TIGR02550; flagellar hook-associated protein 3 806577 flgL 6319765 flgL Clostridium botulinum E3 str. Alaska E43 flagellar hook-associated protein 3 YP_001920170.1 805369 D 508767 CDS YP_001920171.1 188587580 6317755 806595..807020 1 NC_010723.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 807020 6317755 CLH_0776 Clostridium botulinum E3 str. Alaska E43 flagellar assembly protein FliW YP_001920171.1 806595 D 508767 CDS YP_001920172.1 188588452 6320283 807025..807240 1 NC_010723.1 identified by match to protein family HMM PF02599; match to protein family HMM TIGR00202; carbon storage regulator 807240 csrA 6320283 csrA Clostridium botulinum E3 str. Alaska E43 carbon storage regulator YP_001920172.1 807025 D 508767 CDS YP_001920173.1 188589585 6319636 807427..807783 1 NC_010723.1 identified by match to protein family HMM PF03646; flaG family protein 807783 6319636 CLH_0778 Clostridium botulinum E3 str. Alaska E43 flaG family protein YP_001920173.1 807427 D 508767 CDS YP_001920174.1 188588022 6318775 807804..808100 1 NC_010723.1 hypothetical protein 808100 6318775 CLH_0779 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920174.1 807804 D 508767 CDS YP_001920175.1 188588945 6319223 808112..808489 1 NC_010723.1 identified by match to protein family HMM PF02561; match to protein family HMM TIGR00208; flagellar protein FliS 808489 fliS 6319223 fliS Clostridium botulinum E3 str. Alaska E43 flagellar protein FliS YP_001920175.1 808112 D 508767 CDS YP_001920176.1 188589902 6318913 808509..810596 1 NC_010723.1 identified by match to protein family HMM PF02465; match to protein family HMM PF07195; flagellar cap protein FliD 810596 6318913 CLH_0781 Clostridium botulinum E3 str. Alaska E43 flagellar cap protein FliD YP_001920176.1 808509 D 508767 CDS YP_001920177.1 188590650 6320352 810601..810927 1 NC_010723.1 hypothetical protein 810927 6320352 CLH_0782 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920177.1 810601 D 508767 CDS YP_001920178.1 188588040 6317912 811036..811215 1 NC_010723.1 hypothetical protein 811215 6317912 CLH_0783 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920178.1 811036 D 508767 CDS YP_001920179.1 188588920 6318253 811632..812444 1 NC_010723.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 812444 6318253 CLH_0784 Clostridium botulinum E3 str. Alaska E43 flagellin YP_001920179.1 811632 D 508767 CDS YP_001920180.1 188590275 6319110 812589..814493 1 NC_010723.1 identified by match to protein family HMM PF00535; family 2 glycosyl transferase 814493 6319110 CLH_0785 Clostridium botulinum E3 str. Alaska E43 family 2 glycosyl transferase YP_001920180.1 812589 D 508767 CDS YP_001920181.1 188590609 6319311 814704..815516 1 NC_010723.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 815516 6319311 CLH_0786 Clostridium botulinum E3 str. Alaska E43 flagellin YP_001920181.1 814704 D 508767 CDS YP_001920182.1 188589904 6319300 815680..817479 1 NC_010723.1 identified by match to protein family HMM PF01973; hypothetical protein 817479 6319300 CLH_0787 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920182.1 815680 D 508767 CDS YP_001920183.1 188589148 6320517 817508..817855 1 NC_010723.1 hypothetical protein 817855 6320517 CLH_0788 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920183.1 817508 D 508767 CDS YP_001920184.1 188588190 6319872 817926..819137 1 NC_010723.1 identified by match to protein family HMM PF01973; hypothetical protein 819137 6319872 CLH_0789 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920184.1 817926 D 508767 CDS YP_001920185.1 188590130 6319134 819262..820209 1 NC_010723.1 undetermined role; similar to CarB protein but much smaller; carbamoyl phosphate synthase-like protein 820209 6319134 CLH_0790 Clostridium botulinum E3 str. Alaska E43 carbamoyl phosphate synthase-like protein YP_001920185.1 819262 D 508767 CDS YP_001920186.1 188589541 6317456 820206..820889 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; putative hydrolase 820889 6317456 CLH_0791 Clostridium botulinum E3 str. Alaska E43 putative hydrolase YP_001920186.1 820206 D 508767 CDS YP_001920187.1 188588581 6320160 820946..821728 1 NC_010723.1 identified by match to protein family HMM PF02348; spore coat polysaccharide biosynthesis protein SpsF 821728 6320160 CLH_0792 Clostridium botulinum E3 str. Alaska E43 spore coat polysaccharide biosynthesis protein SpsF YP_001920187.1 820946 D 508767 CDS YP_001920188.1 188588864 6318304 821764..822513 1 NC_010723.1 CalS11 822513 6318304 CLH_0793 Clostridium botulinum E3 str. Alaska E43 CalS11 YP_001920188.1 821764 D 508767 CDS YP_001920189.1 188587978 6320590 822586..823464 1 NC_010723.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; methyltransferase type 12 823464 6320590 CLH_0794 Clostridium botulinum E3 str. Alaska E43 methyltransferase type 12 YP_001920189.1 822586 D 508767 CDS YP_001920190.1 188588704 6318235 823534..825129 1 NC_010723.1 hypothetical protein 825129 6318235 CLH_0795 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920190.1 823534 D 508767 CDS YP_001920191.1 188587755 6318609 825444..825557 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 825557 6318609 CLH_0796 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920191.1 825444 D 508767 CDS YP_001920192.1 188590143 6319089 825700..826674 1 NC_010723.1 glycosyltransferase 826674 6319089 CLH_0797 Clostridium botulinum E3 str. Alaska E43 glycosyltransferase YP_001920192.1 825700 D 508767 CDS YP_001920193.1 188589367 6318427 826700..827755 1 NC_010723.1 identified by match to protein family HMM PF03102; match to protein family HMM PF08666; sialic acid synthase 827755 6318427 CLH_0798 Clostridium botulinum E3 str. Alaska E43 sialic acid synthase YP_001920193.1 826700 D 508767 CDS YP_001920194.1 188589163 6319265 827789..828805 1 NC_010723.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; FlmA protein 828805 6319265 CLH_0799 Clostridium botulinum E3 str. Alaska E43 FlmA protein YP_001920194.1 827789 D 508767 CDS YP_001920195.1 188588237 6320055 829113..830330 1 NC_010723.1 hypothetical protein 830330 6320055 CLH_0800 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920195.1 829113 D 508767 CDS YP_001920196.1 188590600 6319595 830366..831370 1 NC_010723.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; putative UDP-glucose 4-epimerase 831370 6319595 CLH_0801 Clostridium botulinum E3 str. Alaska E43 putative UDP-glucose 4-epimerase YP_001920196.1 830366 D 508767 CDS YP_001920197.1 188589728 6320269 831395..833404 1 NC_010723.1 identified by match to protein family HMM PF00515; match to protein family HMM PF00884; match to protein family HMM PF07719; sulfatase-domain-containing protein 833404 6320269 CLH_0802 Clostridium botulinum E3 str. Alaska E43 sulfatase-domain-containing protein YP_001920197.1 831395 D 508767 CDS YP_001920198.1 188589135 6318997 833870..834712 1 NC_010723.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 834712 6318997 CLH_0803 Clostridium botulinum E3 str. Alaska E43 flagellin YP_001920198.1 833870 D 508767 CDS YP_001920199.1 188588215 6318478 835500..835901 1 NC_010723.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgB 835901 flgB 6318478 flgB Clostridium botulinum E3 str. Alaska E43 flagellar basal body rod protein FlgB YP_001920199.1 835500 D 508767 CDS YP_001920200.1 188590422 6319668 835916..836323 1 NC_010723.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 836323 flgC 6319668 flgC Clostridium botulinum E3 str. Alaska E43 flagellar basal body rod protein FlgC YP_001920200.1 835916 D 508767 CDS YP_001920201.1 188590322 6320617 836337..836663 1 NC_010723.1 identified by match to protein family HMM PF02049; match to protein family HMM TIGR00205; flagellar hook-basal body complex protein 836663 fliE 6320617 fliE Clostridium botulinum E3 str. Alaska E43 flagellar hook-basal body complex protein YP_001920201.1 836337 D 508767 CDS YP_001920202.1 188589083 6318934 836688..838250 1 NC_010723.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 838250 fliF 6318934 fliF Clostridium botulinum E3 str. Alaska E43 flagellar MS-ring protein YP_001920202.1 836688 D 508767 CDS YP_001920203.1 188589824 6318780 838257..839273 1 NC_010723.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 839273 fliG 6318780 fliG Clostridium botulinum E3 str. Alaska E43 flagellar motor switch protein G YP_001920203.1 838257 D 508767 CDS YP_001920204.1 188590074 6318481 839257..840042 1 NC_010723.1 flagellar assembly protein 840042 6318481 CLH_0809 Clostridium botulinum E3 str. Alaska E43 flagellar assembly protein YP_001920204.1 839257 D 508767 CDS YP_001920205.1 188588315 6317592 840054..841361 1 NC_010723.1 identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR03496; match to protein family HMM TIGR03497; flagellar protein export ATPase FliI 841361 fliI 6317592 fliI Clostridium botulinum E3 str. Alaska E43 flagellar protein export ATPase FliI YP_001920205.1 840054 D 508767 CDS YP_001920206.1 188588665 6319984 841396..841839 1 NC_010723.1 identified by match to protein family HMM TIGR02473; flagellar export protein FliJ 841839 fliJ 6319984 fliJ Clostridium botulinum E3 str. Alaska E43 flagellar export protein FliJ YP_001920206.1 841396 D 508767 CDS YP_001920207.1 188589399 6319246 841846..843150 1 NC_010723.1 identified by match to protein family HMM PF02120; putative flagellar hook-length control protein FliK 843150 6319246 CLH_0812 Clostridium botulinum E3 str. Alaska E43 putative flagellar hook-length control protein FliK YP_001920207.1 841846 D 508767 CDS YP_001920208.1 188588066 6318636 843162..844127 1 NC_010723.1 identified by match to protein family HMM PF03963; flagellar hook assembly protein FlgD 844127 6318636 CLH_0813 Clostridium botulinum E3 str. Alaska E43 flagellar hook assembly protein FlgD YP_001920208.1 843162 D 508767 CDS YP_001920209.1 188588804 6318744 844131..844520 1 NC_010723.1 identified by match to protein family HMM TIGR02530; flagellar operon protein 844520 6318744 CLH_0814 Clostridium botulinum E3 str. Alaska E43 flagellar operon protein YP_001920209.1 844131 D 508767 CDS YP_001920210.1 188587648 6318387 844663..845763 1 NC_010723.1 identified by match to protein family HMM PF00460; match to protein family HMM PF06429; match to protein family HMM TIGR03506; flagellar hook protein FlgE 845763 6318387 CLH_0815 Clostridium botulinum E3 str. Alaska E43 flagellar hook protein FlgE YP_001920210.1 844663 D 508767 CDS YP_001920211.1 188588515 6319776 845960..847054 1 NC_010723.1 identified by match to protein family HMM PF00460; match to protein family HMM PF06429; match to protein family HMM TIGR03506; flagellar hook protein FlgE 847054 6319776 CLH_0816 Clostridium botulinum E3 str. Alaska E43 flagellar hook protein FlgE YP_001920211.1 845960 D 508767 CDS YP_001920212.1 188589816 6318753 847150..847341 1 NC_010723.1 identified by match to protein family HMM PF06289; hypothetical protein 847341 6318753 CLH_0817 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920212.1 847150 D 508767 CDS YP_001920213.1 188590744 6320100 847357..848160 1 NC_010723.1 identified by match to protein family HMM PF01618; chemotaxis protein MotA 848160 6320100 CLH_0818 Clostridium botulinum E3 str. Alaska E43 chemotaxis protein MotA YP_001920213.1 847357 D 508767 CDS YP_001920214.1 188590401 6318181 848163..848906 1 NC_010723.1 identified by match to protein family HMM PF00691; chemotaxis protein MotB 848906 6318181 CLH_0819 Clostridium botulinum E3 str. Alaska E43 chemotaxis protein MotB YP_001920214.1 848163 D 508767 CDS YP_001920215.1 188588882 6320320 848912..849391 1 NC_010723.1 identified by match to protein family HMM PF03748; flagellar basal body-associated protein FliL 849391 fliL 6320320 fliL Clostridium botulinum E3 str. Alaska E43 flagellar basal body-associated protein FliL YP_001920215.1 848912 D 508767 CDS YP_001920216.1 188588534 6319009 849405..849791 1 NC_010723.1 putative flagellar biosynthesis protein 849791 6319009 CLH_0821 Clostridium botulinum E3 str. Alaska E43 putative flagellar biosynthesis protein YP_001920216.1 849405 D 508767 CDS YP_001920217.1 188589499 6318485 849794..850573 1 NC_010723.1 identified by match to protein family HMM PF00813; match to protein family HMM TIGR01103; flagellar biosynthetic protein FliP 850573 fliP 6318485 fliP Clostridium botulinum E3 str. Alaska E43 flagellar biosynthetic protein FliP YP_001920217.1 849794 D 508767 CDS YP_001920218.1 188590018 6318950 850585..850854 1 NC_010723.1 identified by match to protein family HMM PF01313; match to protein family HMM TIGR01402; flagellar biosynthetic protein FliQ 850854 fliQ 6318950 fliQ Clostridium botulinum E3 str. Alaska E43 flagellar biosynthetic protein FliQ YP_001920218.1 850585 D 508767 CDS YP_001920219.1 188588311 6319662 850872..852704 1 NC_010723.1 FlhB is a membrane protein responsible for substrate specificity in switching from rod/hook-type export to filament-type export; FliR is required for export of flagellar proteins, although a specific role has not yet been determined; bifunctional flagellar biosynthesis protein FliR/FlhB 852704 6319662 CLH_0824 Clostridium botulinum E3 str. Alaska E43 bifunctional flagellar biosynthesis protein FliR/FlhB YP_001920219.1 850872 D 508767 CDS YP_001920220.1 188589940 6319998 852734..854800 1 NC_010723.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 854800 flhA 6319998 flhA Clostridium botulinum E3 str. Alaska E43 flagellar biosynthesis protein FlhA YP_001920220.1 852734 D 508767 CDS YP_001920221.1 188588736 6319843 854800..856011 1 NC_010723.1 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 856011 flhF 6319843 flhF Clostridium botulinum E3 str. Alaska E43 flagellar biosynthesis regulator FlhF YP_001920221.1 854800 D 508767 CDS YP_001920222.1 188588085 6317413 856005..856865 1 NC_010723.1 identified by match to protein family HMM PF01656; chromosome partitioning ATPase protein, MinD family 856865 6317413 CLH_0827 Clostridium botulinum E3 str. Alaska E43 chromosome partitioning ATPase protein, MinD family YP_001920222.1 856005 D 508767 CDS YP_001920223.1 188590150 6318695 856876..857511 1 NC_010723.1 identified by match to protein family HMM PF07238; type IV pilus assembly protein PilZ 857511 6318695 CLH_0828 Clostridium botulinum E3 str. Alaska E43 type IV pilus assembly protein PilZ YP_001920223.1 856876 D 508767 CDS YP_001920224.1 188589224 6317727 857619..858347 1 NC_010723.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02479; match to protein family HMM TIGR02937; RNA polymerase sigma-D factor 858347 6317727 CLH_0829 Clostridium botulinum E3 str. Alaska E43 RNA polymerase sigma-D factor YP_001920224.1 857619 D 508767 CDS YP_001920225.1 188588654 6317473 858360..858998 1 NC_010723.1 hypothetical protein 858998 6317473 CLH_0830 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920225.1 858360 D 508767 CDS YP_001920226.1 188587895 6319981 859076..859198 1 NC_010723.1 hypothetical protein 859198 6319981 CLH_0831 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920226.1 859076 D 508767 CDS YP_001920227.1 188590007 6317779 859199..859972 1 NC_010723.1 makes up the distal portion of the flagellar basal body rod; the Clostridia have two adjacent copies of the FlgG gene; flagellar basal body rod protein FlgG 859972 flgG 6317779 flgG Clostridium botulinum E3 str. Alaska E43 flagellar basal body rod protein FlgG YP_001920227.1 859199 D 508767 CDS YP_001920228.1 188589304 6320476 859986..860756 1 NC_010723.1 makes up the distal portion of the flagellar basal body rod; the Clostridia have 2 adjacent copies of the FlgG gene; flagellar basal body rod protein FlgG 860756 flgG 6320476 flgG Clostridium botulinum E3 str. Alaska E43 flagellar basal body rod protein FlgG YP_001920228.1 859986 D 508767 CDS YP_001920229.1 188589830 6317276 complement(861006..862646) 1 NC_010723.1 catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase 862646 6317276 CLH_0834 Clostridium botulinum E3 str. Alaska E43 putative manganese-dependent inorganic pyrophosphatase YP_001920229.1 861006 R 508767 CDS YP_001920230.1 188590127 6319671 862792..865338 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; putative calcium-translocating P-type ATPase, PMCA-type 865338 6319671 CLH_0835 Clostridium botulinum E3 str. Alaska E43 putative calcium-translocating P-type ATPase, PMCA-type YP_001920230.1 862792 D 508767 CDS YP_001920231.1 188588965 6320444 complement(865596..866027) 1 NC_010723.1 hypothetical protein 866027 6320444 CLH_0836 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920231.1 865596 R 508767 CDS YP_001920232.1 188588266 6319860 866476..867021 1 NC_010723.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; transcriptional regulator BotR, P-21 867021 botR 6319860 botR Clostridium botulinum E3 str. Alaska E43 transcriptional regulator BotR, P-21 YP_001920232.1 866476 D 508767 CDS YP_001920233.1 188589694 6319839 867014..867235 1 NC_010723.1 UviB-like protein 867235 6319839 CLH_0838 Clostridium botulinum E3 str. Alaska E43 UviB-like protein YP_001920233.1 867014 D 508767 CDS YP_001920234.1 188590508 6319599 867456..868379 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 868379 6319599 CLH_0839 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920234.1 867456 D 508767 CDS YP_001920235.1 188590329 6320603 868558..870867 1 NC_010723.1 identified by match to protein family HMM PF05362; ATP-dependent protease 870867 6320603 CLH_0840 Clostridium botulinum E3 str. Alaska E43 ATP-dependent protease YP_001920235.1 868558 D 508767 CDS YP_001920236.1 188587770 6318327 871220..871555 1 NC_010723.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; match to protein family HMM TIGR02886; anti-sigma F factor antagonist 871555 spoIIAA 6318327 spoIIAA Clostridium botulinum E3 str. Alaska E43 anti-sigma F factor antagonist YP_001920236.1 871220 D 508767 CDS YP_001920237.1 188588474 6319877 871572..872003 1 NC_010723.1 binds to sigma F preventing its association with RNA polymerase during sporulation; anti-sigma F factor 872003 spoIIAB 6319877 spoIIAB Clostridium botulinum E3 str. Alaska E43 anti-sigma F factor YP_001920237.1 871572 D 508767 CDS YP_001920238.1 188589198 6319218 872013..872768 1 NC_010723.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore.; sporulation sigma factor SigF 872768 sigF 6319218 sigF Clostridium botulinum E3 str. Alaska E43 sporulation sigma factor SigF YP_001920238.1 872013 D 508767 CDS YP_001920239.1 188590545 6318581 873360..873818 1 NC_010723.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838; stage V sporulation protein AC 873818 spoVAC 6318581 spoVAC Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein AC YP_001920239.1 873360 D 508767 CDS YP_001920240.1 188588884 6317962 873974..874993 1 NC_010723.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845; stage V sporulation protein AD 874993 spoVAD 6317962 spoVAD Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein AD YP_001920240.1 873974 D 508767 CDS YP_001920241.1 188589651 6318858 875017..875373 1 NC_010723.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839; stage V sporulation protein AE 875373 spoVAE 6318858 spoVAE Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein AE YP_001920241.1 875017 D 508767 CDS YP_001920242.1 188590385 6320496 875487..878003 1 NC_010723.1 identified by match to protein family HMM PF00122; putative calcium-transporting ATPase 878003 6320496 CLH_0847 Clostridium botulinum E3 str. Alaska E43 putative calcium-transporting ATPase YP_001920242.1 875487 D 508767 CDS YP_001920243.1 188587649 6319204 878009..879703 1 NC_010723.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; putative competence protein 879703 6319204 CLH_0848 Clostridium botulinum E3 str. Alaska E43 putative competence protein YP_001920243.1 878009 D 508767 CDS YP_001920244.1 188588435 6319956 879733..880767 1 NC_010723.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 880767 holA 6319956 holA Clostridium botulinum E3 str. Alaska E43 DNA polymerase III subunit delta YP_001920244.1 879733 D 508767 CDS YP_001920245.1 188589456 6319934 complement(880809..881072) 1 NC_010723.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 881072 rpsT 6319934 rpsT Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S20 YP_001920245.1 880809 R 508767 CDS YP_001920246.1 188590042 6317493 881390..882361 1 NC_010723.1 Initiates the rapid degradation of small, acid-soluble proteins during spore germination; germination protease 882361 gpr 6317493 gpr Clostridium botulinum E3 str. Alaska E43 germination protease YP_001920246.1 881390 D 508767 CDS YP_001920247.1 188587661 6320339 882776..883843 1 NC_010723.1 identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867; stage II sporulation protein P 883843 6320339 CLH_0852 Clostridium botulinum E3 str. Alaska E43 stage II sporulation protein P YP_001920247.1 882776 D 508767 CDS YP_001920248.1 188588172 6319602 883968..884348 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 884348 6319602 CLH_0853 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920248.1 883968 D 508767 CDS YP_001920249.1 188589078 6319456 884492..886294 1 NC_010723.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 886294 lepA 6319456 lepA Clostridium botulinum E3 str. Alaska E43 GTP-binding protein LepA YP_001920249.1 884492 D 508767 CDS YP_001920250.1 188588627 6318460 886405..887544 1 NC_010723.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 887544 6318460 CLH_0855 Clostridium botulinum E3 str. Alaska E43 coproporphyrinogen III oxidase YP_001920250.1 886405 D 508767 CDS YP_001920251.1 188589336 6318925 887729..888760 1 NC_010723.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 888760 hrcA 6318925 hrcA Clostridium botulinum E3 str. Alaska E43 heat-inducible transcription repressor YP_001920251.1 887729 D 508767 CDS YP_001920252.1 188590078 6318835 888799..889422 1 NC_010723.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 889422 grpE 6318835 grpE Clostridium botulinum E3 str. Alaska E43 heat shock protein GrpE YP_001920252.1 888799 D 508767 CDS YP_001920253.1 188588330 6317244 889502..891352 1 NC_010723.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 891352 dnaK 6317244 dnaK Clostridium botulinum E3 str. Alaska E43 molecular chaperone DnaK YP_001920253.1 889502 D 508767 CDS YP_001920254.1 188589041 6319916 891456..892577 1 NC_010723.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 892577 dnaJ 6319916 dnaJ Clostridium botulinum E3 str. Alaska E43 chaperone protein DnaJ YP_001920254.1 891456 D 508767 CDS YP_001920255.1 188589757 6319785 892868..894418 1 NC_010723.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460; ferredoxin-nitrite reductase 894418 6319785 CLH_0860 Clostridium botulinum E3 str. Alaska E43 ferredoxin-nitrite reductase YP_001920255.1 892868 D 508767 CDS YP_001920256.1 188590510 6318567 894678..895337 1 NC_010723.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 895337 trmB 6318567 trmB Clostridium botulinum E3 str. Alaska E43 tRNA (guanine-N(7)-)-methyltransferase YP_001920256.1 894678 D 508767 CDS YP_001920257.1 188587914 6318080 895505..896446 1 NC_010723.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 896446 prmA 6318080 prmA Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L11 methyltransferase YP_001920257.1 895505 D 508767 CDS YP_001920258.1 188588657 6319422 896539..897303 1 NC_010723.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 897303 6319422 CLH_0863 Clostridium botulinum E3 str. Alaska E43 16S ribosomal RNA methyltransferase RsmE YP_001920258.1 896539 D 508767 CDS YP_001920259.1 188589299 6317731 897303..898607 1 NC_010723.1 identified by match to protein family HMM PF00919; match to protein family HMM PF01938; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579; hypothetical protein 898607 6317731 CLH_0864 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920259.1 897303 D 508767 CDS YP_001920260.1 188589245 6317320 898810..899154 1 NC_010723.1 identified by match to protein family HMM PF01230; HIT family protein 899154 6317320 CLH_0865 Clostridium botulinum E3 str. Alaska E43 HIT family protein YP_001920260.1 898810 D 508767 CDS YP_001920261.1 188590220 6318733 899291..899467 1 NC_010723.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 899467 rpsU 6318733 rpsU Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S21 YP_001920261.1 899291 D 508767 CDS YP_001920262.1 188588083 6320452 899497..899946 1 NC_010723.1 identified by match to protein family HMM PF09424; GatB/Yqey domain protein 899946 6320452 CLH_0867 Clostridium botulinum E3 str. Alaska E43 GatB/Yqey domain protein YP_001920262.1 899497 D 508767 CDS YP_001920263.1 188588805 6318693 900199..900477 1 NC_010723.1 identified by match to protein family HMM PF07241; match to protein family HMM TIGR02856; sporulation protein YqfC 900477 yqfC 6318693 yqfC Clostridium botulinum E3 str. Alaska E43 sporulation protein YqfC YP_001920263.1 900199 D 508767 CDS YP_001920264.1 188588007 6318388 900480..901610 1 NC_010723.1 identified by match to protein family HMM PF06898; match to protein family HMM TIGR02876; sporulation protein YqfD 901610 yqfD 6318388 yqfD Clostridium botulinum E3 str. Alaska E43 sporulation protein YqfD YP_001920264.1 900480 D 508767 CDS YP_001920265.1 188588808 6318897 901645..903705 1 NC_010723.1 identified by match to protein family HMM PF01966; match to protein family HMM PF07697; match to protein family HMM PF07698; match to protein family HMM TIGR00277; membrane protein containing HD superfamily hydrolase domain 903705 6318897 CLH_0870 Clostridium botulinum E3 str. Alaska E43 membrane protein containing HD superfamily hydrolase domain YP_001920265.1 901645 D 508767 CDS YP_001920266.1 188588423 6318118 903718..904218 1 NC_010723.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; putative metalloprotease 904218 6318118 CLH_0871 Clostridium botulinum E3 str. Alaska E43 putative metalloprotease YP_001920266.1 903718 D 508767 CDS YP_001920267.1 188590620 6320015 904243..904944 1 NC_010723.1 identified by match to protein family HMM PF01219; match to protein family HMM PF01569; diacylglycerol kinase/PAP2 family protein 904944 6320015 CLH_0872 Clostridium botulinum E3 str. Alaska E43 diacylglycerol kinase/PAP2 family protein YP_001920267.1 904243 D 508767 CDS YP_001920268.1 188590271 6318490 905417..906304 1 NC_010723.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 906304 era 6318490 era Clostridium botulinum E3 str. Alaska E43 GTP-binding protein Era YP_001920268.1 905417 D 508767 CDS YP_001920269.1 188587696 6320343 906329..907078 1 NC_010723.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 907078 recO 6320343 recO Clostridium botulinum E3 str. Alaska E43 DNA repair protein RecO YP_001920269.1 906329 D 508767 CDS YP_001920270.1 188587701 6318222 907085..907702 1 NC_010723.1 identified by match to protein family HMM PF00627; UBA/TS-N domain-containing protein 907702 6318222 CLH_0875 Clostridium botulinum E3 str. Alaska E43 UBA/TS-N domain-containing protein YP_001920270.1 907085 D 508767 CDS YP_001920271.1 188589027 6318957 907745..908374 1 NC_010723.1 identified by match to protein family HMM PF00571; match to protein family HMM PF08220; match to protein family HMM PF08279; hypothetical protein 908374 6318957 CLH_0876 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920271.1 907745 D 508767 CDS YP_001920272.1 188589386 6317631 908464..911091 1 NC_010723.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 911091 ppdK 6317631 ppdK Clostridium botulinum E3 str. Alaska E43 pyruvate phosphate dikinase YP_001920272.1 908464 D 508767 CDS YP_001920273.1 188590354 6318680 complement(911382..912449) 1 NC_010723.1 identified by match to protein family HMM TIGR02906; spore coat protein 912449 6318680 CLH_0878 Clostridium botulinum E3 str. Alaska E43 spore coat protein YP_001920273.1 911382 R 508767 CDS YP_001920274.1 188589548 6317666 912636..913664 1 NC_010723.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 913664 6317666 CLH_0879 Clostridium botulinum E3 str. Alaska E43 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_001920274.1 912636 D 508767 CDS YP_001920275.1 188590265 6320214 913913..915691 1 NC_010723.1 synthesizes RNA primers at the replication forks; DNA primase 915691 dnaG 6320214 dnaG Clostridium botulinum E3 str. Alaska E43 DNA primase YP_001920275.1 913913 D 508767 CDS YP_001920276.1 188587782 6317440 915697..916821 1 NC_010723.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 916821 rpoD 6317440 rpoD Clostridium botulinum E3 str. Alaska E43 RNA polymerase sigma factor RpoD YP_001920276.1 915697 D 508767 CDS YP_001920277.1 188588701 6318661 916914..917600 1 NC_010723.1 identified by match to protein family HMM PF04816; Bcl-2 family protein 917600 6318661 CLH_0882 Clostridium botulinum E3 str. Alaska E43 Bcl-2 family protein YP_001920277.1 916914 D 508767 CDS YP_001920278.1 188588519 6318598 917718..918509 1 NC_010723.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein 918509 6318598 CLH_0883 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920278.1 917718 D 508767 CDS YP_001920279.1 188589431 6317412 918566..918802 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 918802 6317412 CLH_0884 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920279.1 918566 D 508767 CDS YP_001920280.1 188588214 6318552 complement(919288..919749) 1 NC_010723.1 identified by match to protein family HMM PF06114; phage protein 919749 6318552 CLH_0885 Clostridium botulinum E3 str. Alaska E43 phage protein YP_001920280.1 919288 R 508767 CDS YP_001920281.1 188587728 6319681 complement(919767..920132) 1 NC_010723.1 identified by match to protein family HMM PF01381; transcriptional regulator 920132 6319681 CLH_0886 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001920281.1 919767 R 508767 CDS YP_001920282.1 188589675 6319778 920387..920896 1 NC_010723.1 hypothetical protein 920896 6319778 CLH_0887 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920282.1 920387 D 508767 CDS YP_001920283.1 188588978 6319348 921657..922073 1 NC_010723.1 hypothetical protein 922073 6319348 CLH_0888 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920283.1 921657 D 508767 CDS YP_001920284.1 188590242 6319462 922063..922218 1 NC_010723.1 hypothetical protein 922218 6319462 CLH_0889 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920284.1 922063 D 508767 CDS YP_001920285.1 188589520 6317337 922219..923529 1 NC_010723.1 sheath tail protein 923529 6317337 CLH_0890 Clostridium botulinum E3 str. Alaska E43 sheath tail protein YP_001920285.1 922219 D 508767 CDS YP_001920286.1 188588395 6319267 923548..924015 1 NC_010723.1 identified by match to protein family HMM PF09393; hypothetical protein 924015 6319267 CLH_0891 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920286.1 923548 D 508767 CDS YP_001920287.1 188587578 6319847 924315..924728 1 NC_010723.1 identified by match to protein family HMM PF08890; hypothetical protein 924728 6319847 CLH_0892 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920287.1 924315 D 508767 CDS YP_001920288.1 188587564 6318386 924924..926873 1 NC_010723.1 hypothetical protein 926873 6318386 CLH_0893 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920288.1 924924 D 508767 CDS YP_001920289.1 188589965 6320273 926873..927535 1 NC_010723.1 identified by match to protein family HMM PF01476; peptidoglycan-binding LysM 927535 6320273 CLH_0894 Clostridium botulinum E3 str. Alaska E43 peptidoglycan-binding LysM YP_001920289.1 926873 D 508767 CDS YP_001920290.1 188589871 6318319 927547..928518 1 NC_010723.1 hypothetical protein 928518 6318319 CLH_0895 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920290.1 927547 D 508767 CDS YP_001920291.1 188589128 6319792 928522..928851 1 NC_010723.1 phage protein 928851 6319792 CLH_0896 Clostridium botulinum E3 str. Alaska E43 phage protein YP_001920291.1 928522 D 508767 CDS YP_001920292.1 188590056 6318771 928844..929251 1 NC_010723.1 phage protein 929251 6318771 CLH_0897 Clostridium botulinum E3 str. Alaska E43 phage protein YP_001920292.1 928844 D 508767 CDS YP_001920293.1 188589377 6320558 929254..930312 1 NC_010723.1 identified by match to protein family HMM PF04865; hypothetical protein 930312 6320558 CLH_0898 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920293.1 929254 D 508767 CDS YP_001920294.1 188589319 6317708 930313..932394 1 NC_010723.1 hypothetical protein 932394 6317708 CLH_0899 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920294.1 930313 D 508767 CDS YP_001920295.1 188588591 6317628 932396..933010 1 NC_010723.1 hypothetical protein 933010 6317628 CLH_0900 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920295.1 932396 D 508767 CDS YP_001920296.1 188587872 6318613 933025..933825 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 933825 6318613 CLH_0901 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920296.1 933025 D 508767 CDS YP_001920297.1 188590499 6317692 933842..934177 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 934177 6317692 CLH_0902 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920297.1 933842 D 508767 CDS YP_001920298.1 188589588 6319095 934170..934304 1 NC_010723.1 identified by match to protein family HMM TIGR01669; phage protein, XkdX family 934304 6319095 CLH_0903 Clostridium botulinum E3 str. Alaska E43 phage protein, XkdX family YP_001920298.1 934170 D 508767 CDS YP_001920299.1 188588691 6319207 934418..934618 1 NC_010723.1 UviB-like protein 934618 6319207 CLH_0904 Clostridium botulinum E3 str. Alaska E43 UviB-like protein YP_001920299.1 934418 D 508767 CDS YP_001920300.1 188589744 6318666 934757..935551 1 NC_010723.1 identified by match to protein family HMM PF01183; glycosyl hydrolase family protein 935551 6318666 CLH_0905 Clostridium botulinum E3 str. Alaska E43 glycosyl hydrolase family protein YP_001920300.1 934757 D 508767 CDS YP_001920301.1 188588886 6320035 935699..935863 1 NC_010723.1 surface lipoprotein-related protein 935863 6320035 CLH_0906 Clostridium botulinum E3 str. Alaska E43 surface lipoprotein-related protein YP_001920301.1 935699 D 508767 CDS YP_001920302.1 188590001 6318860 complement(935886..936452) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 936452 6318860 CLH_0907 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001920302.1 935886 R 508767 CDS YP_001920303.1 188589281 6319789 936819..937865 1 NC_010723.1 hypothetical protein 937865 6319789 CLH_0908 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920303.1 936819 D 508767 CDS YP_001920304.1 188588116 6317722 937884..938921 1 NC_010723.1 hypothetical protein 938921 6317722 CLH_0909 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920304.1 937884 D 508767 CDS YP_001920305.1 188590280 6319726 939071..940180 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; multiple sugar-binding transport ATP-binding protein MsmK 940180 6319726 CLH_0910 Clostridium botulinum E3 str. Alaska E43 multiple sugar-binding transport ATP-binding protein MsmK YP_001920305.1 939071 D 508767 CDS YP_001920306.1 188589897 6320186 940202..941143 1 NC_010723.1 hypothetical protein 941143 6320186 CLH_0911 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920306.1 940202 D 508767 CDS YP_001920307.1 188588809 6318863 941305..942321 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; HTH-type transcriptional regulator MalR 942321 6318863 CLH_0912 Clostridium botulinum E3 str. Alaska E43 HTH-type transcriptional regulator MalR YP_001920307.1 941305 D 508767 CDS YP_001920308.1 188587737 6318119 942496..943983 1 NC_010723.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 943983 malQ 6318119 malQ Clostridium botulinum E3 str. Alaska E43 4-alpha-glucanotransferase YP_001920308.1 942496 D 508767 CDS YP_001920309.1 188588339 6319687 943983..946343 1 NC_010723.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase 946343 6319687 CLH_0914 Clostridium botulinum E3 str. Alaska E43 glycogen phosphorylase YP_001920309.1 943983 D 508767 CDS YP_001920310.1 188590458 6318362 946860..948599 1 NC_010723.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 948599 kdpA 6318362 kdpA Clostridium botulinum E3 str. Alaska E43 potassium-transporting ATPase subunit A YP_001920310.1 946860 D 508767 CDS YP_001920311.1 188590366 6320088 948615..950681 1 NC_010723.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 950681 kdpB 6320088 kdpB Clostridium botulinum E3 str. Alaska E43 potassium-transporting ATPase subunit B YP_001920311.1 948615 D 508767 CDS YP_001920312.1 188589515 6318290 950699..951304 1 NC_010723.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 951304 kdpC 6318290 kdpC Clostridium botulinum E3 str. Alaska E43 potassium-transporting ATPase subunit C YP_001920312.1 950699 D 508767 CDS YP_001920313.1 188588108 6318065 951467..954169 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF02702; sensor protein KdpD 954169 6318065 CLH_0918 Clostridium botulinum E3 str. Alaska E43 sensor protein KdpD YP_001920313.1 951467 D 508767 CDS YP_001920314.1 188590123 6320334 954162..954869 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; KDP operon transcriptional regulatory protein KdpE 954869 6320334 CLH_0919 Clostridium botulinum E3 str. Alaska E43 KDP operon transcriptional regulatory protein KdpE YP_001920314.1 954162 D 508767 CDS YP_001920315.1 188588990 6317484 complement(955088..955951) 1 NC_010723.1 identified by match to protein family HMM PF06325; 50S ribosomal protein L11 methyltransferase 955951 prmA 6317484 prmA Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L11 methyltransferase YP_001920315.1 955088 R 508767 CDS YP_001920316.1 188588735 6319105 956188..957147 1 NC_010723.1 Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 957147 6319105 CLH_0921 Clostridium botulinum E3 str. Alaska E43 2-hydroxyacid dehydrogenase YP_001920316.1 956188 D 508767 CDS YP_001920317.1 188587601 6317318 complement(957380..958168) 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD hydrolase 958168 6317318 CLH_0922 Clostridium botulinum E3 str. Alaska E43 HAD hydrolase YP_001920317.1 957380 R 508767 CDS YP_001920318.1 188590577 6319691 958385..959122 1 NC_010723.1 identified by match to protein family HMM PF02811; putative hydrolase 959122 6319691 CLH_0923 Clostridium botulinum E3 str. Alaska E43 putative hydrolase YP_001920318.1 958385 D 508767 CDS YP_001920319.1 188589459 6320183 959192..959635 1 NC_010723.1 identified by match to protein family HMM PF00583; spermine/spermidine acetyltransferase 959635 6320183 CLH_0924 Clostridium botulinum E3 str. Alaska E43 spermine/spermidine acetyltransferase YP_001920319.1 959192 D 508767 CDS YP_001920320.1 188590087 6318566 960141..961568 1 NC_010723.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 961568 6318566 CLH_0925 Clostridium botulinum E3 str. Alaska E43 sodium:alanine symporter family protein YP_001920320.1 960141 D 508767 CDS YP_001920321.1 188588419 6317463 complement(961669..961941) 1 NC_010723.1 identified by match to protein family HMM PF00708; acylphosphatase 961941 6317463 CLH_0926 Clostridium botulinum E3 str. Alaska E43 acylphosphatase YP_001920321.1 961669 R 508767 CDS YP_001920322.1 188587720 6319758 962072..962491 1 NC_010723.1 identified by match to protein family HMM PF00334; nucleoside diphosphate kinase 962491 6319758 CLH_0927 Clostridium botulinum E3 str. Alaska E43 nucleoside diphosphate kinase YP_001920322.1 962072 D 508767 CDS YP_001920323.1 188590259 6319062 complement(962586..963650) 1 NC_010723.1 identified by match to protein family HMM PF01547; spermidine/putrescine ABC transporter spermidine/putrescine-binding protein 963650 6319062 CLH_0928 Clostridium botulinum E3 str. Alaska E43 spermidine/putrescine ABC transporter spermidine/putrescine-binding protein YP_001920323.1 962586 R 508767 CDS YP_001920324.1 188589537 6318047 complement(963637..964437) 1 NC_010723.1 identified by match to protein family HMM PF00528; spermidine/putrescine transport system permease protein PotC 964437 6318047 CLH_0929 Clostridium botulinum E3 str. Alaska E43 spermidine/putrescine transport system permease protein PotC YP_001920324.1 963637 R 508767 CDS YP_001920325.1 188589699 6319284 complement(964431..965273) 1 NC_010723.1 identified by match to protein family HMM PF00528; putrescine transport system permease protein PotH 965273 6319284 CLH_0930 Clostridium botulinum E3 str. Alaska E43 putrescine transport system permease protein PotH YP_001920325.1 964431 R 508767 CDS YP_001920326.1 188590193 6318577 complement(965266..966315) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; match to protein family HMM TIGR01187; spermidine/putrescine import ATP-binding protein PotA 966315 6318577 CLH_0931 Clostridium botulinum E3 str. Alaska E43 spermidine/putrescine import ATP-binding protein PotA YP_001920326.1 965266 R 508767 CDS YP_001920327.1 188587862 6317728 complement(966338..966877) 1 NC_010723.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 966877 6317728 CLH_0932 Clostridium botulinum E3 str. Alaska E43 DNA-binding protein YP_001920327.1 966338 R 508767 CDS YP_001920328.1 188588376 6319444 967244..968347 1 NC_010723.1 GNAT family acetyltransferase 968347 6319444 CLH_0933 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001920328.1 967244 D 508767 CDS YP_001920329.1 188588523 6318236 968420..969277 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 969277 6318236 CLH_0934 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920329.1 968420 D 508767 CDS YP_001920330.1 188588995 6320512 complement(969434..970834) 1 NC_010723.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; amino acid carrier protein AlsT 970834 6320512 CLH_0935 Clostridium botulinum E3 str. Alaska E43 amino acid carrier protein AlsT YP_001920330.1 969434 R 508767 CDS YP_001920331.1 188588878 6319440 complement(971156..973681) 1 NC_010723.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; membrane carboxypeptidase MrcB 973681 6319440 CLH_0936 Clostridium botulinum E3 str. Alaska E43 membrane carboxypeptidase MrcB YP_001920331.1 971156 R 508767 CDS YP_001920332.1 188588093 6318870 973783..974430 1 NC_010723.1 identified by match to protein family HMM PF09560; match to protein family HMM TIGR02832; sporulation protein YunB 974430 6318870 CLH_0937 Clostridium botulinum E3 str. Alaska E43 sporulation protein YunB YP_001920332.1 973783 D 508767 CDS YP_001920333.1 188589501 6318214 complement(974529..975050) 1 NC_010723.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 975050 hpt 6318214 hpt Clostridium botulinum E3 str. Alaska E43 hypoxanthine phosphoribosyltransferase YP_001920333.1 974529 R 508767 CDS YP_001920334.1 188588594 6318952 975607..977424 1 NC_010723.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR03156; GTP binding protein 977424 6318952 CLH_0939 Clostridium botulinum E3 str. Alaska E43 GTP binding protein YP_001920334.1 975607 D 508767 CDS YP_001920335.1 188588455 6318634 977663..978571 1 NC_010723.1 identified by match to protein family HMM PF01909; nucleotidyltransferase domain protein 978571 6318634 CLH_0940 Clostridium botulinum E3 str. Alaska E43 nucleotidyltransferase domain protein YP_001920335.1 977663 D 508767 CDS YP_001920336.1 188587774 6318708 978592..980019 1 NC_010723.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 980019 6318708 CLH_0941 Clostridium botulinum E3 str. Alaska E43 GntR family transcriptional regulator YP_001920336.1 978592 D 508767 CDS YP_001920337.1 188590709 6319625 980007..980654 1 NC_010723.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 980654 6319625 CLH_0942 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920337.1 980007 D 508767 CDS YP_001920338.1 188589174 6318737 980841..981581 1 NC_010723.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 981581 6318737 CLH_0943 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920338.1 980841 D 508767 CDS YP_001920339.1 188589797 6317812 complement(981912..982247) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 982247 6317812 CLH_0944 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920339.1 981912 R 508767 CDS YP_001920340.1 188590565 6317392 982648..983466 1 NC_010723.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 983466 speD 6317392 speD Clostridium botulinum E3 str. Alaska E43 S-adenosylmethionine decarboxylase YP_001920340.1 982648 D 508767 CDS YP_001920341.1 188589999 6318790 983482..984939 1 NC_010723.1 identified by match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711; arginine decarboxylase 984939 6318790 CLH_0946 Clostridium botulinum E3 str. Alaska E43 arginine decarboxylase YP_001920341.1 983482 D 508767 CDS YP_001920342.1 188589068 6319737 984939..985793 1 NC_010723.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 985793 speE 6319737 speE Clostridium botulinum E3 str. Alaska E43 spermidine synthase YP_001920342.1 984939 D 508767 CDS YP_001920343.1 188588605 6320264 985847..987046 1 NC_010723.1 identified by match to protein family HMM PF03435; saccharopine dehydrogenase 987046 6320264 CLH_0948 Clostridium botulinum E3 str. Alaska E43 saccharopine dehydrogenase YP_001920343.1 985847 D 508767 CDS YP_001920344.1 188587896 6317600 987140..988282 1 NC_010723.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase 988282 nspC 6317600 nspC Clostridium botulinum E3 str. Alaska E43 carboxynorspermidine decarboxylase YP_001920344.1 987140 D 508767 CDS YP_001920345.1 188590516 6317780 complement(988376..990535) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; two-component sensor kinase 990535 6317780 CLH_0950 Clostridium botulinum E3 str. Alaska E43 two-component sensor kinase YP_001920345.1 988376 R 508767 CDS YP_001920346.1 188589787 6318043 990817..991662 1 NC_010723.1 identified by match to protein family HMM PF00491; match to protein family HMM TIGR01230; agmatinase 991662 speB 6318043 speB Clostridium botulinum E3 str. Alaska E43 agmatinase YP_001920346.1 990817 D 508767 CDS YP_001920347.1 188589325 6320474 complement(991777..992862) 1 NC_010723.1 identified by match to protein family HMM PF00465; match to protein family HMM PF01761; glycerol dehydrogenase 992862 6320474 CLH_0952 Clostridium botulinum E3 str. Alaska E43 glycerol dehydrogenase YP_001920347.1 991777 R 508767 CDS YP_001920348.1 188588154 6318877 993183..995168 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; putative membrane-associated methyl-accepting chemotaxis protein fused to hamp domain 995168 6318877 CLH_0953 Clostridium botulinum E3 str. Alaska E43 putative membrane-associated methyl-accepting chemotaxis protein fused to hamp domain YP_001920348.1 993183 D 508767 CDS YP_001920349.1 188587928 6318921 995378..996247 1 NC_010723.1 identified by match to protein family HMM PF04055; radical SAM 996247 6318921 CLH_0954 Clostridium botulinum E3 str. Alaska E43 radical SAM YP_001920349.1 995378 D 508767 CDS YP_001920350.1 188587635 6318983 996469..997050 1 NC_010723.1 hypothetical protein 997050 6318983 CLH_0955 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920350.1 996469 D 508767 CDS YP_001920351.1 188590168 6319864 997324..997920 1 NC_010723.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 997920 ruvA 6319864 ruvA Clostridium botulinum E3 str. Alaska E43 Holliday junction DNA helicase RuvA YP_001920351.1 997324 D 508767 CDS YP_001920352.1 188589876 6318838 997956..998990 1 NC_010723.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 998990 ruvB 6318838 ruvB Clostridium botulinum E3 str. Alaska E43 Holliday junction DNA helicase RuvB YP_001920352.1 997956 D 508767 CDS YP_001920353.1 188589166 6318591 999009..1000034 1 NC_010723.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1000034 queA 6318591 queA Clostridium botulinum E3 str. Alaska E43 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001920353.1 999009 D 508767 CDS YP_001920354.1 188588030 6319011 1000178..1001317 1 NC_010723.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1001317 tgt 6319011 tgt Clostridium botulinum E3 str. Alaska E43 queuine tRNA-ribosyltransferase YP_001920354.1 1000178 D 508767 CDS YP_001920355.1 188589373 6319213 1001426..1001701 1 NC_010723.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1001701 yajC 6319213 yajC Clostridium botulinum E3 str. Alaska E43 preprotein translocase subunit YajC YP_001920355.1 1001426 D 508767 CDS YP_001920356.1 188588235 6317847 1001763..1002137 1 NC_010723.1 hypothetical protein 1002137 6317847 CLH_0961 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920356.1 1001763 D 508767 CDS YP_001920357.1 188587560 6319619 1002384..1004546 1 NC_010723.1 identified by match to protein family HMM PF02355; match to protein family HMM PF07549; match to protein family HMM TIGR00916; match to protein family HMM TIGR00966; match to protein family HMM TIGR01129; protein export protein SecD 1004546 6319619 CLH_0962 Clostridium botulinum E3 str. Alaska E43 protein export protein SecD YP_001920357.1 1002384 D 508767 CDS YP_001920358.1 188590091 6319418 1004687..1005550 1 NC_010723.1 identified by match to protein family HMM PF01368; DHH domain-containing protein 1005550 6319418 CLH_0963 Clostridium botulinum E3 str. Alaska E43 DHH domain-containing protein YP_001920358.1 1004687 D 508767 CDS YP_001920359.1 188589743 6317753 1005591..1006109 1 NC_010723.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1006109 apt 6317753 apt Clostridium botulinum E3 str. Alaska E43 adenine phosphoribosyltransferase YP_001920359.1 1005591 D 508767 CDS YP_001920360.1 188588536 6320034 1006216..1008402 1 NC_010723.1 identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; GTP pyrophosphokinase 1008402 relA 6320034 relA Clostridium botulinum E3 str. Alaska E43 GTP pyrophosphokinase YP_001920360.1 1006216 D 508767 CDS YP_001920361.1 188589909 6318468 1008414..1008863 1 NC_010723.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1008863 dtd 6318468 dtd Clostridium botulinum E3 str. Alaska E43 D-tyrosyl-tRNA(Tyr) deacylase YP_001920361.1 1008414 D 508767 CDS YP_001920362.1 188590675 6319574 1008894..1009496 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 1009496 6319574 CLH_0967 Clostridium botulinum E3 str. Alaska E43 metallo-beta-lactamase family protein YP_001920362.1 1008894 D 508767 CDS YP_001920363.1 188588125 6320178 1009506..1010927 1 NC_010723.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1010927 6320178 CLH_0968 Clostridium botulinum E3 str. Alaska E43 coproporphyrinogen III oxidase YP_001920363.1 1009506 D 508767 CDS YP_001920364.1 188588876 6317844 1010993..1012246 1 NC_010723.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1012246 hisS 6317844 hisS Clostridium botulinum E3 str. Alaska E43 histidyl-tRNA synthetase YP_001920364.1 1010993 D 508767 CDS YP_001920365.1 188588113 6318868 1012472..1014271 1 NC_010723.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1014271 aspS 6318868 aspS Clostridium botulinum E3 str. Alaska E43 aspartyl-tRNA synthetase YP_001920365.1 1012472 D 508767 CDS YP_001920366.1 188590691 6319183 complement(1014334..1015260) 1 NC_010723.1 protein tyrosine phosphatase II superfamily protein 1015260 6319183 CLH_0971 Clostridium botulinum E3 str. Alaska E43 protein tyrosine phosphatase II superfamily protein YP_001920366.1 1014334 R 508767 CDS YP_001920367.1 188588304 6319120 1015444..1016142 1 NC_010723.1 identified by match to protein family HMM PF04474; hypothetical protein 1016142 6319120 CLH_0972 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920367.1 1015444 D 508767 CDS YP_001920368.1 188588441 6320010 1016286..1016606 1 NC_010723.1 hypothetical protein 1016606 6320010 CLH_0973 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920368.1 1016286 D 508767 CDS YP_001920369.1 188589363 6319474 1016738..1017493 1 NC_010723.1 identified by match to protein family HMM PF01022; match to protein family HMM PF02579; match to protein family HMM PF08279; ArsR family transcriptional regulator 1017493 6319474 CLH_0974 Clostridium botulinum E3 str. Alaska E43 ArsR family transcriptional regulator YP_001920369.1 1016738 D 508767 CDS YP_001920370.1 188589884 6318105 1017826..1019127 1 NC_010723.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1019127 hom 6318105 hom Clostridium botulinum E3 str. Alaska E43 homoserine dehydrogenase YP_001920370.1 1017826 D 508767 CDS YP_001920371.1 188589181 6319230 1019494..1020054 1 NC_010723.1 identified by match to protein family HMM PF04309; glycerol-3-phosphate responsive antiterminator 1020054 6319230 CLH_0976 Clostridium botulinum E3 str. Alaska E43 glycerol-3-phosphate responsive antiterminator YP_001920371.1 1019494 D 508767 CDS YP_001920372.1 188590122 6317702 1020153..1021649 1 NC_010723.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1021649 glpK 6317702 glpK Clostridium botulinum E3 str. Alaska E43 glycerol kinase YP_001920372.1 1020153 D 508767 CDS YP_001920373.1 188588904 6317646 1021805..1023235 1 NC_010723.1 identified by match to protein family HMM PF01266; match to protein family HMM PF04324; glycerol-3-phosphate dehydrogenase, glpa 1023235 6317646 CLH_0978 Clostridium botulinum E3 str. Alaska E43 glycerol-3-phosphate dehydrogenase, glpa YP_001920373.1 1021805 D 508767 CDS YP_001920374.1 188588641 6317296 1023248..1024501 1 NC_010723.1 identified by match to protein family HMM PF07992; NAD 1024501 6317296 CLH_0979 Clostridium botulinum E3 str. Alaska E43 NAD YP_001920374.1 1023248 D 508767 CDS YP_001920375.1 188588106 6317768 1024503..1024856 1 NC_010723.1 identified by match to protein family HMM PF07892; molybdopterin oxidoreductase, 4Fe-4S cluster-binding subunit 1024856 6317768 CLH_0980 Clostridium botulinum E3 str. Alaska E43 molybdopterin oxidoreductase, 4Fe-4S cluster-binding subunit YP_001920375.1 1024503 D 508767 CDS YP_001920376.1 188588821 6320332 complement(1025323..1026633) 1 NC_010723.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1026633 6320332 CLH_0981 Clostridium botulinum E3 str. Alaska E43 aspartate kinase YP_001920376.1 1025323 R 508767 CDS YP_001920377.1 188589807 6318175 1027107..1028438 1 NC_010723.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase, type I 1028438 glnA 6318175 glnA Clostridium botulinum E3 str. Alaska E43 glutamine synthetase, type I YP_001920377.1 1027107 D 508767 CDS YP_001920378.1 188590297 6320116 1028461..1029024 1 NC_010723.1 identified by match to protein family HMM PF03861; nitrogen regulator 1029024 6320116 CLH_0983 Clostridium botulinum E3 str. Alaska E43 nitrogen regulator YP_001920378.1 1028461 D 508767 CDS YP_001920379.1 188590351 6320349 1029153..1033724 1 NC_010723.1 identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898; glutamate synthase [NADPH] large chain 1033724 6320349 CLH_0984 Clostridium botulinum E3 str. Alaska E43 glutamate synthase [NADPH] large chain YP_001920379.1 1029153 D 508767 CDS YP_001920380.1 188587614 6320479 1033736..1035208 1 NC_010723.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317; glutamate synthase [NADPH] small chain 1035208 6320479 CLH_0985 Clostridium botulinum E3 str. Alaska E43 glutamate synthase [NADPH] small chain YP_001920380.1 1033736 D 508767 CDS YP_001920381.1 188587971 6319840 1035434..1036861 1 NC_010723.1 identified by match to protein family HMM PF00324; amino acid permease family protein 1036861 6319840 CLH_0986 Clostridium botulinum E3 str. Alaska E43 amino acid permease family protein YP_001920381.1 1035434 D 508767 CDS YP_001920382.1 188589056 6317665 1036981..1037277 1 NC_010723.1 hypothetical protein 1037277 6317665 CLH_0987 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920382.1 1036981 D 508767 CDS YP_001920383.1 188589435 6319573 1037640..1039265 1 NC_010723.1 hypothetical protein 1039265 6319573 CLH_0988 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920383.1 1037640 D 508767 CDS YP_001920384.1 188590479 6317832 complement(1039442..1039924) 1 NC_010723.1 identified by match to protein family HMM PF02559; CarD family transcriptional regulator 1039924 6317832 CLH_0989 Clostridium botulinum E3 str. Alaska E43 CarD family transcriptional regulator YP_001920384.1 1039442 R 508767 CDS YP_001920385.1 188589419 6318967 1040264..1041271 1 NC_010723.1 hypothetical protein 1041271 6318967 CLH_0990 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920385.1 1040264 D 508767 CDS YP_001920386.1 188590310 6320389 1041410..1041949 1 NC_010723.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubrerythrin 1041949 6320389 CLH_0991 Clostridium botulinum E3 str. Alaska E43 rubrerythrin YP_001920386.1 1041410 D 508767 CDS YP_001920387.1 188587567 6318701 1042293..1042904 1 NC_010723.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1042904 udk 6318701 udk Clostridium botulinum E3 str. Alaska E43 uridine kinase YP_001920387.1 1042293 D 508767 CDS YP_001920388.1 188588451 6317967 complement(1043095..1043703) 1 NC_010723.1 identified by similarity to GB:CAJ67405.1; hypothetical protein 1043703 6317967 CLH_0993 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920388.1 1043095 R 508767 CDS YP_001920389.1 188588865 6319635 1043952..1044407 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1044407 6319635 CLH_0994 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920389.1 1043952 D 508767 CDS YP_001920390.1 188590519 6320591 complement(1044578..1046179) 1 NC_010723.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704; Na/Pi-cotransporter family protein/PhoU family protein 1046179 6320591 CLH_0995 Clostridium botulinum E3 str. Alaska E43 Na/Pi-cotransporter family protein/PhoU family protein YP_001920390.1 1044578 R 508767 CDS YP_001920391.1 188587610 6320172 complement(1046301..1047248) 1 NC_010723.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1047248 rnz 6320172 rnz Clostridium botulinum E3 str. Alaska E43 ribonuclease Z YP_001920391.1 1046301 R 508767 CDS YP_001920392.1 188588141 6319526 1047401..1048057 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD hydrolase 1048057 6319526 CLH_0997 Clostridium botulinum E3 str. Alaska E43 HAD hydrolase YP_001920392.1 1047401 D 508767 CDS YP_001920393.1 188589458 6319173 1048221..1049369 1 NC_010723.1 identified by match to protein family HMM PF01594; hypothetical protein 1049369 6319173 CLH_0998 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920393.1 1048221 D 508767 CDS YP_001920394.1 188590390 6318565 1049464..1049847 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1049847 6318565 CLH_0999 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920394.1 1049464 D 508767 CDS YP_001920395.1 188588397 6320468 1049837..1050478 1 NC_010723.1 putative normocyte binding protein 2a 1050478 6320468 CLH_1000 Clostridium botulinum E3 str. Alaska E43 putative normocyte binding protein 2a YP_001920395.1 1049837 D 508767 CDS YP_001920396.1 188589565 6319929 1050478..1050774 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1050774 6319929 CLH_1001 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920396.1 1050478 D 508767 CDS YP_001920397.1 188590658 6317374 1050795..1053263 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1053263 6317374 CLH_1002 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920397.1 1050795 D 508767 CDS YP_001920398.1 188587704 6320167 1053321..1053530 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1053530 6320167 CLH_1003 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920398.1 1053321 D 508767 CDS YP_001920399.1 188588345 6320584 1053878..1055938 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 1055938 6320584 CLH_1004 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001920399.1 1053878 D 508767 CDS YP_001920400.1 188590618 6320123 1056079..1056402 1 NC_010723.1 identified by match to protein family HMM PF00085; thioredoxin family protein 1056402 6320123 CLH_1005 Clostridium botulinum E3 str. Alaska E43 thioredoxin family protein YP_001920400.1 1056079 D 508767 CDS YP_001920401.1 188590660 6318796 1056673..1056981 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1056981 6318796 CLH_1006 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920401.1 1056673 D 508767 CDS YP_001920402.1 188588798 6320169 complement(1057050..1058270) 1 NC_010723.1 catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 1058270 ilvA 6320169 ilvA Clostridium botulinum E3 str. Alaska E43 threonine dehydratase YP_001920402.1 1057050 R 508767 CDS YP_001920403.1 188587885 6318740 1058598..1059362 1 NC_010723.1 identified by match to protein family HMM PF06738; membrane spanning protein 1059362 6318740 CLH_1008 Clostridium botulinum E3 str. Alaska E43 membrane spanning protein YP_001920403.1 1058598 D 508767 CDS YP_001920404.1 188590209 6319339 1059363..1059821 1 NC_010723.1 membrane spanning protein 1059821 6319339 CLH_1009 Clostridium botulinum E3 str. Alaska E43 membrane spanning protein YP_001920404.1 1059363 D 508767 CDS YP_001920405.1 188590591 6317370 1060065..1060958 1 NC_010723.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux protein 1060958 6317370 CLH_1010 Clostridium botulinum E3 str. Alaska E43 cation efflux protein YP_001920405.1 1060065 D 508767 CDS YP_001920406.1 188587804 6318408 complement(1061239..1062231) 1 NC_010723.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00367; putative K+-dependent Na+/Ca+ exchanger-like protein 1062231 6318408 CLH_1011 Clostridium botulinum E3 str. Alaska E43 putative K+-dependent Na+/Ca+ exchanger-like protein YP_001920406.1 1061239 R 508767 CDS YP_001920407.1 188588724 6319772 1062660..1064216 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1064216 6319772 CLH_1012 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001920407.1 1062660 D 508767 CDS YP_001920408.1 188589218 6320567 1064592..1065884 1 NC_010723.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 1065884 brnQ 6320567 brnQ Clostridium botulinum E3 str. Alaska E43 branched-chain amino acid transport system II carrier protein YP_001920408.1 1064592 D 508767 CDS YP_001920409.1 188589184 6317557 complement(1066087..1066950) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1066950 6317557 CLH_1014 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920409.1 1066087 R 508767 CDS YP_001920410.1 188589451 6317417 1067332..1067715 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1067715 6317417 CLH_1015 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920410.1 1067332 D 508767 CDS YP_001920411.1 188589657 6320549 1067789..1067983 1 NC_010723.1 hypothetical protein 1067983 6320549 CLH_1016 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920411.1 1067789 D 508767 CDS YP_001920412.1 188589102 6320608 1068942..1070177 1 NC_010723.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1070177 glyA 6320608 glyA Clostridium botulinum E3 str. Alaska E43 serine hydroxymethyltransferase YP_001920412.1 1068942 D 508767 CDS YP_001920413.1 188588034 6318233 1070468..1071382 1 NC_010723.1 Ser/Thr protein phosphatase family protein 1071382 6318233 CLH_1019 Clostridium botulinum E3 str. Alaska E43 Ser/Thr protein phosphatase family protein YP_001920413.1 1070468 D 508767 CDS YP_001920414.1 188590192 6318243 1071430..1072365 1 NC_010723.1 identified by match to protein family HMM PF01244; membrane dipeptidase 1072365 6318243 CLH_1020 Clostridium botulinum E3 str. Alaska E43 membrane dipeptidase YP_001920414.1 1071430 D 508767 CDS YP_001920415.1 188587780 6317435 1072757..1073500 1 NC_010723.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1073500 fabG 6317435 fabG Clostridium botulinum E3 str. Alaska E43 3-ketoacyl-ACP reductase YP_001920415.1 1072757 D 508767 CDS YP_001920416.1 188588086 6318277 complement(1073720..1074748) 1 NC_010723.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1074748 ilvE 6318277 ilvE Clostridium botulinum E3 str. Alaska E43 branched-chain amino acid aminotransferase YP_001920416.1 1073720 R 508767 CDS YP_001920417.1 188590467 6318741 complement(1074901..1076799) 1 NC_010723.1 identified by match to protein family HMM PF00795; match to protein family HMM PF02540; match to protein family HMM TIGR00552; glutamine-dependent NAD(+) synthetase 1076799 nadE 6318741 nadE Clostridium botulinum E3 str. Alaska E43 glutamine-dependent NAD(+) synthetase YP_001920417.1 1074901 R 508767 CDS YP_001920418.1 188589976 6320374 1077100..1077543 1 NC_010723.1 identified by match to protein family HMM PF01957; nodulation efficiency protein D 1077543 6320374 CLH_1024 Clostridium botulinum E3 str. Alaska E43 nodulation efficiency protein D YP_001920418.1 1077100 D 508767 CDS YP_001920419.1 188589038 6319353 1077536..1078492 1 NC_010723.1 identified by match to protein family HMM PF01145; spfh domain/band 7 family protein 1078492 6319353 CLH_1025 Clostridium botulinum E3 str. Alaska E43 spfh domain/band 7 family protein YP_001920419.1 1077536 D 508767 CDS YP_001920420.1 188590064 6318969 1078918..1080228 1 NC_010723.1 identified by match to protein family HMM PF00375; proton glutamate symport protein 1080228 6318969 CLH_1026 Clostridium botulinum E3 str. Alaska E43 proton glutamate symport protein YP_001920420.1 1078918 D 508767 CDS YP_001920421.1 188587922 6317788 1080509..1081030 1 NC_010723.1 putative lipoprotein 1081030 6317788 CLH_1027 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001920421.1 1080509 D 508767 CDS YP_001920422.1 188590068 6318523 complement(1081337..1082725) 1 NC_010723.1 identified by match to protein family HMM PF01554; Na+ driven multidrug efflux pump 1082725 6318523 CLH_1028 Clostridium botulinum E3 str. Alaska E43 Na+ driven multidrug efflux pump YP_001920422.1 1081337 R 508767 CDS YP_001920423.1 188587918 6317710 1082700..1082819 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1082819 6317710 CLH_1029 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920423.1 1082700 D 508767 CDS YP_001920424.1 188588636 6318242 1082816..1083628 1 NC_010723.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1083628 6318242 CLH_1030 Clostridium botulinum E3 str. Alaska E43 MerR family transcriptional regulator YP_001920424.1 1082816 D 508767 CDS YP_001920425.1 188589766 6320076 1084054..1084860 1 NC_010723.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1084860 6320076 CLH_1031 Clostridium botulinum E3 str. Alaska E43 amino acid ABC transporter substrate-binding protein YP_001920425.1 1084054 D 508767 CDS YP_001920426.1 188590526 6320086 1084876..1085517 1 NC_010723.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; L-cystine transport system permease protein TcyB 1085517 6320086 CLH_1032 Clostridium botulinum E3 str. Alaska E43 L-cystine transport system permease protein TcyB YP_001920426.1 1084876 D 508767 CDS YP_001920427.1 188588334 6320288 1085534..1086214 1 NC_010723.1 identified by match to protein family HMM PF00005; ATP-binding protein 1086214 6320288 CLH_1033 Clostridium botulinum E3 str. Alaska E43 ATP-binding protein YP_001920427.1 1085534 D 508767 CDS YP_001920428.1 188589275 6318032 1086365..1086520 1 NC_010723.1 hypothetical protein 1086520 6318032 CLH_1034 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920428.1 1086365 D 508767 CDS YP_001920429.1 188589998 6317820 1086625..1087881 1 NC_010723.1 identified by match to protein family HMM PF00654; voltage gated chloride channel family 1087881 6317820 CLH_1035 Clostridium botulinum E3 str. Alaska E43 voltage gated chloride channel family YP_001920429.1 1086625 D 508767 CDS YP_001920430.1 188588439 6319736 1087985..1088875 1 NC_010723.1 identified by match to protein family HMM PF00248; oxidoreductase YdhF 1088875 6319736 CLH_1036 Clostridium botulinum E3 str. Alaska E43 oxidoreductase YdhF YP_001920430.1 1087985 D 508767 CDS YP_001920431.1 188590619 6319794 1089135..1092881 1 NC_010723.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857; phosphoribosylformylglycinamidine synthase 1092881 6319794 CLH_1037 Clostridium botulinum E3 str. Alaska E43 phosphoribosylformylglycinamidine synthase YP_001920431.1 1089135 D 508767 CDS YP_001920432.1 188587816 6318797 1093290..1093769 1 NC_010723.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit 1093769 purE 6318797 purE Clostridium botulinum E3 str. Alaska E43 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001920432.1 1093290 D 508767 CDS YP_001920433.1 188589747 6319798 1093769..1094476 1 NC_010723.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1094476 purC 6319798 purC Clostridium botulinum E3 str. Alaska E43 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001920433.1 1093769 D 508767 CDS YP_001920434.1 188589238 6320436 1094619..1096019 1 NC_010723.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1096019 purF 6320436 purF Clostridium botulinum E3 str. Alaska E43 amidophosphoribosyltransferase YP_001920434.1 1094619 D 508767 CDS YP_001920435.1 188588764 6318985 1096029..1097030 1 NC_010723.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1097030 purM 6318985 purM Clostridium botulinum E3 str. Alaska E43 phosphoribosylaminoimidazole synthetase YP_001920435.1 1096029 D 508767 CDS YP_001920436.1 188590115 6319098 1097018..1097632 1 NC_010723.1 identified by match to protein family HMM PF00551; match to protein family HMM TIGR00639; phosphoribosylglycinamide formyltransferase 1097632 purN 6319098 purN Clostridium botulinum E3 str. Alaska E43 phosphoribosylglycinamide formyltransferase YP_001920436.1 1097018 D 508767 CDS YP_001920437.1 188589264 6317830 1097782..1099287 1 NC_010723.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1099287 purH 6317830 purH Clostridium botulinum E3 str. Alaska E43 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001920437.1 1097782 D 508767 CDS YP_001920438.1 188589098 6318572 1099539..1100789 1 NC_010723.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1100789 purD 6318572 purD Clostridium botulinum E3 str. Alaska E43 phosphoribosylamine--glycine ligase YP_001920438.1 1099539 D 508767 CDS YP_001920439.1 188588238 6318923 complement(1100888..1101361) 1 NC_010723.1 hypothetical protein 1101361 6318923 CLH_1045 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920439.1 1100888 R 508767 CDS YP_001920440.1 188590248 6319596 complement(1101601..1102041) 1 NC_010723.1 hypothetical protein 1102041 6319596 CLH_1046 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920440.1 1101601 R 508767 CDS YP_001920441.1 188589497 6317384 complement(1102284..1102757) 1 NC_010723.1 hypothetical protein 1102757 6317384 CLH_1047 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920441.1 1102284 R 508767 CDS YP_001920442.1 188590199 6319392 1102910..1106302 1 NC_010723.1 hypothetical protein 1106302 6319392 CLH_1048 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920442.1 1102910 D 508767 CDS YP_001920443.1 188589473 6317654 1106780..1107994 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1107994 6317654 CLH_1049 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920443.1 1106780 D 508767 CDS YP_001920444.1 188588366 6317826 1107995..1109410 1 NC_010723.1 identified by match to protein family HMM PF02629; CoA-binding protein 1109410 6317826 CLH_1050 Clostridium botulinum E3 str. Alaska E43 CoA-binding protein YP_001920444.1 1107995 D 508767 CDS YP_001920445.1 188587685 6319710 1109749..1110204 1 NC_010723.1 identified by match to protein family HMM PF04397; LytR family transcriptional regulator 1110204 6319710 CLH_1051 Clostridium botulinum E3 str. Alaska E43 LytR family transcriptional regulator YP_001920445.1 1109749 D 508767 CDS YP_001920446.1 188590706 6318274 1110206..1110904 1 NC_010723.1 hypothetical protein 1110904 6318274 CLH_1052 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920446.1 1110206 D 508767 CDS YP_001920447.1 188589975 6318406 complement(1111037..1111879) 1 NC_010723.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 1111879 6318406 CLH_1053 Clostridium botulinum E3 str. Alaska E43 DegV family protein YP_001920447.1 1111037 R 508767 CDS YP_001920448.1 188588846 6319352 1112015..1112593 1 NC_010723.1 identified by match to protein family HMM PF00440; putative transcriptional regulator, AcrR family 1112593 6319352 CLH_1054 Clostridium botulinum E3 str. Alaska E43 putative transcriptional regulator, AcrR family YP_001920448.1 1112015 D 508767 CDS YP_001920449.1 188587961 6318727 complement(1112695..1114584) 1 NC_010723.1 identified by match to protein family HMM PF02687; ABC transporter permease 1114584 6318727 CLH_1055 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001920449.1 1112695 R 508767 CDS YP_001920450.1 188588996 6317299 complement(1114586..1115335) 1 NC_010723.1 identified by match to protein family HMM PF00005; bacitracin export ATP-binding protein BceA 1115335 6317299 CLH_1056 Clostridium botulinum E3 str. Alaska E43 bacitracin export ATP-binding protein BceA YP_001920450.1 1114586 R 508767 CDS YP_001920451.1 188588028 6319620 complement(1115465..1117009) 1 NC_010723.1 ABC transporter permease 1117009 6319620 CLH_1057 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001920451.1 1115465 R 508767 CDS YP_001920452.1 188588540 6317957 complement(1116999..1117766) 1 NC_010723.1 identified by match to protein family HMM PF00005; bacitracin export ATP-binding protein BceA 1117766 6317957 CLH_1058 Clostridium botulinum E3 str. Alaska E43 bacitracin export ATP-binding protein BceA YP_001920452.1 1116999 R 508767 CDS YP_001920453.1 188587544 6318721 complement(1117776..1118807) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; two-component sensor kinase 1118807 6318721 CLH_1059 Clostridium botulinum E3 str. Alaska E43 two-component sensor kinase YP_001920453.1 1117776 R 508767 CDS YP_001920454.1 188590358 6319128 complement(1118804..1119472) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1119472 6319128 CLH_1060 Clostridium botulinum E3 str. Alaska E43 DNA-binding response regulator YP_001920454.1 1118804 R 508767 CDS YP_001920455.1 188589478 6318594 1119687..1120382 1 NC_010723.1 putative F pilin acetylation protein 1120382 6318594 CLH_1061 Clostridium botulinum E3 str. Alaska E43 putative F pilin acetylation protein YP_001920455.1 1119687 D 508767 CDS YP_001920456.1 188588054 6317793 1120676..1121497 1 NC_010723.1 hypothetical protein 1121497 6317793 CLH_1062 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920456.1 1120676 D 508767 CDS YP_001920457.1 188590624 6319078 1121702..1121854 1 NC_010723.1 hypothetical protein 1121854 6319078 CLH_1063 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920457.1 1121702 D 508767 CDS YP_001920458.1 188589555 6318086 1122223..1122903 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 1122903 6318086 CLH_1064 Clostridium botulinum E3 str. Alaska E43 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_001920458.1 1122223 D 508767 CDS YP_001920459.1 188588835 6318383 1123003..1124370 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; two-component sensor histidine kinase 1124370 6318383 CLH_1065 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001920459.1 1123003 D 508767 CDS YP_001920460.1 188589261 6317901 1124461..1125297 1 NC_010723.1 hypothetical protein 1125297 6317901 CLH_1066 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920460.1 1124461 D 508767 CDS YP_001920461.1 188590178 6318770 1125329..1126378 1 NC_010723.1 ABC transporter substrate-binding protein 1126378 6318770 CLH_1067 Clostridium botulinum E3 str. Alaska E43 ABC transporter substrate-binding protein YP_001920461.1 1125329 D 508767 CDS YP_001920462.1 188589183 6318296 1126605..1128023 1 NC_010723.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 1128023 uhpT 6318296 uhpT Clostridium botulinum E3 str. Alaska E43 sugar phosphate antiporter YP_001920462.1 1126605 D 508767 CDS YP_001920463.1 188590147 6317416 1128411..1129508 1 NC_010723.1 hypothetical protein 1129508 6317416 CLH_1069 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920463.1 1128411 D 508767 CDS YP_001920464.1 188588158 6317643 1130227..1131276 1 NC_010723.1 hypothetical protein 1131276 6317643 CLH_1070 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920464.1 1130227 D 508767 CDS YP_001920465.1 188589152 6318463 1131312..1132241 1 NC_010723.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1132241 panE 6318463 panE Clostridium botulinum E3 str. Alaska E43 2-dehydropantoate 2-reductase YP_001920465.1 1131312 D 508767 CDS YP_001920466.1 188589619 6319377 1132463..1132885 1 NC_010723.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 1132885 6319377 CLH_1072 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, MarR family YP_001920466.1 1132463 D 508767 CDS YP_001920467.1 188587866 6320303 1133163..1133726 1 NC_010723.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; match to protein family HMM TIGR02954; RNA polymerase sigma-70 factor family protein 1133726 6320303 CLH_1073 Clostridium botulinum E3 str. Alaska E43 RNA polymerase sigma-70 factor family protein YP_001920467.1 1133163 D 508767 CDS YP_001920468.1 188588626 6317542 1133719..1134789 1 NC_010723.1 hypothetical protein 1134789 6317542 CLH_1074 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920468.1 1133719 D 508767 CDS YP_001920469.1 188589355 6317705 1135200..1135760 1 NC_010723.1 identified by match to protein family HMM PF09335; DedA family membrane protein 1135760 6317705 CLH_1075 Clostridium botulinum E3 str. Alaska E43 DedA family membrane protein YP_001920469.1 1135200 D 508767 CDS YP_001920470.1 188588169 6317917 1135919..1136845 1 NC_010723.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 1136845 6317917 CLH_1076 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920470.1 1135919 D 508767 CDS YP_001920471.1 188590158 6319472 1137029..1137532 1 NC_010723.1 hypothetical protein 1137532 6319472 CLH_1077 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920471.1 1137029 D 508767 CDS YP_001920472.1 188588507 6317284 complement(1137652..1138302) 1 NC_010723.1 putative lipoprotein 1138302 6317284 CLH_1078 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001920472.1 1137652 R 508767 CDS YP_001920473.1 188587598 6318352 1138553..1139002 1 NC_010723.1 identified by match to protein family HMM PF01047; MarR-family transcriptional regulator 1139002 6318352 CLH_1079 Clostridium botulinum E3 str. Alaska E43 MarR-family transcriptional regulator YP_001920473.1 1138553 D 508767 CDS YP_001920474.1 188590229 6319557 1139017..1139985 1 NC_010723.1 identified by match to protein family HMM PF08541; match to protein family HMM PF08545; match to protein family HMM TIGR00747; 3-oxoacyl-(acyl-carrier-protein) synthase III 1139985 fabH 6319557 fabH Clostridium botulinum E3 str. Alaska E43 3-oxoacyl-(acyl-carrier-protein) synthase III YP_001920474.1 1139017 D 508767 CDS YP_001920475.1 188590547 6320471 1140100..1140324 1 NC_010723.1 identified by match to protein family HMM PF00550; acyl carrier protein 1140324 6320471 CLH_1081 Clostridium botulinum E3 str. Alaska E43 acyl carrier protein YP_001920475.1 1140100 D 508767 CDS YP_001920476.1 188588890 6317982 1140434..1141375 1 NC_010723.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151; enoyl-ACP reductase 1141375 6317982 CLH_1082 Clostridium botulinum E3 str. Alaska E43 enoyl-ACP reductase YP_001920476.1 1140434 D 508767 CDS YP_001920477.1 188587993 6317273 1141368..1142309 1 NC_010723.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 1142309 fabD 6317273 fabD Clostridium botulinum E3 str. Alaska E43 malonyl CoA-acyl carrier protein transacylase YP_001920477.1 1141368 D 508767 CDS YP_001920478.1 188590363 6317530 1142330..1143070 1 NC_010723.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1143070 fabG 6317530 fabG Clostridium botulinum E3 str. Alaska E43 3-ketoacyl-ACP reductase YP_001920478.1 1142330 D 508767 CDS YP_001920479.1 188589249 6320527 1143088..1144329 1 NC_010723.1 identified by match to protein family HMM PF00109; match to protein family HMM PF02801; match to protein family HMM TIGR03150; 3-oxoacyl-ACP synthase 1144329 fabF 6320527 fabF Clostridium botulinum E3 str. Alaska E43 3-oxoacyl-ACP synthase YP_001920479.1 1143088 D 508767 CDS YP_001920480.1 188590754 6317685 1144341..1144835 1 NC_010723.1 identified by match to protein family HMM PF00364; match to protein family HMM TIGR00531; acetyl-CoA carboxylase, biotin carboxyl carrier protein 1144835 accB 6317685 accB Clostridium botulinum E3 str. Alaska E43 acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_001920480.1 1144341 D 508767 CDS YP_001920481.1 188587579 6320347 1144841..1145269 1 NC_010723.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1145269 fabZ 6320347 fabZ Clostridium botulinum E3 str. Alaska E43 (3R)-hydroxymyristoyl-ACP dehydratase YP_001920481.1 1144841 D 508767 CDS YP_001920482.1 188588041 6320282 1145279..1146631 1 NC_010723.1 identified by match to protein family HMM PF00289; match to protein family HMM PF02785; match to protein family HMM PF02786; match to protein family HMM PF08443; match to protein family HMM TIGR00514; biotin carboxylase 1146631 accC 6320282 accC Clostridium botulinum E3 str. Alaska E43 biotin carboxylase YP_001920482.1 1145279 D 508767 CDS YP_001920483.1 188588942 6318254 1146624..1147499 1 NC_010723.1 identified by match to protein family HMM TIGR00515; acetyl-CoA carboxylase, carboxyl transferase subunit beta 1147499 accD 6318254 accD Clostridium botulinum E3 str. Alaska E43 acetyl-CoA carboxylase, carboxyl transferase subunit beta YP_001920483.1 1146624 D 508767 CDS YP_001920484.1 188588491 6318022 1147492..1148316 1 NC_010723.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1148316 accA 6318022 accA Clostridium botulinum E3 str. Alaska E43 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001920484.1 1147492 D 508767 CDS YP_001920485.1 188589441 6320384 1148498..1149439 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1149439 6320384 CLH_1091 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920485.1 1148498 D 508767 CDS YP_001920486.1 188587545 6318417 1149473..1149886 1 NC_010723.1 identified by match to protein family HMM PF09021; HutP superfamily 1149886 6318417 CLH_1092 Clostridium botulinum E3 str. Alaska E43 HutP superfamily YP_001920486.1 1149473 D 508767 CDS YP_001920487.1 188588454 6319129 1150307..1151107 1 NC_010723.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase/reductase family oxidoreductase 1151107 6319129 CLH_1093 Clostridium botulinum E3 str. Alaska E43 short chain dehydrogenase/reductase family oxidoreductase YP_001920487.1 1150307 D 508767 CDS YP_001920488.1 188589836 6319667 1151498..1152514 1 NC_010723.1 identified by match to protein family HMM PF04392; ABC transporter substrate-binding protein 1152514 6319667 CLH_1094 Clostridium botulinum E3 str. Alaska E43 ABC transporter substrate-binding protein YP_001920488.1 1151498 D 508767 CDS YP_001920489.1 188590749 6320140 1152517..1153419 1 NC_010723.1 identified by match to protein family HMM PF02653; ABC transporter 1153419 6320140 CLH_1095 Clostridium botulinum E3 str. Alaska E43 ABC transporter YP_001920489.1 1152517 D 508767 CDS YP_001920490.1 188590188 6320205 1153385..1154179 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF02463; phosphonates import ATP-binding protein PhnC 2 1154179 6320205 CLH_1096 Clostridium botulinum E3 str. Alaska E43 phosphonates import ATP-binding protein PhnC 2 YP_001920490.1 1153385 D 508767 CDS YP_001920491.1 188589234 6317785 1154567..1157122 1 NC_010723.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738; match to protein family HMM TIGR03311; selenium-dependent molybdenum hydroxylase 1 1157122 6317785 CLH_1097 Clostridium botulinum E3 str. Alaska E43 selenium-dependent molybdenum hydroxylase 1 YP_001920491.1 1154567 D 508767 CDS YP_001920492.1 188590763 6317789 1157208..1157885 1 NC_010723.1 hypothetical protein 1157885 6317789 CLH_1098 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920492.1 1157208 D 508767 CDS YP_001920493.1 188588489 6320166 1157885..1158907 1 NC_010723.1 identified by match to protein family HMM PF00994; molybdopterin biosynthesis protein 1158907 6320166 CLH_1099 Clostridium botulinum E3 str. Alaska E43 molybdopterin biosynthesis protein YP_001920493.1 1157885 D 508767 CDS YP_001920494.1 188588938 6320382 1158920..1159399 1 NC_010723.1 identified by match to protein family HMM PF01967; match to protein family HMM TIGR00581; molybdenum cofactor biosynthesis protein C 1159399 moaC 6320382 moaC Clostridium botulinum E3 str. Alaska E43 molybdenum cofactor biosynthesis protein C YP_001920494.1 1158920 D 508767 CDS YP_001920495.1 188588003 6318905 1159460..1160440 1 NC_010723.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666; molybdenum cofactor biosynthesis protein A 1160440 moaA 6318905 moaA Clostridium botulinum E3 str. Alaska E43 molybdenum cofactor biosynthesis protein A YP_001920495.1 1159460 D 508767 CDS YP_001920496.1 188589396 6319242 1160443..1160892 1 NC_010723.1 identified by match to protein family HMM PF03473; mosc domain protein 1160892 6319242 CLH_1102 Clostridium botulinum E3 str. Alaska E43 mosc domain protein YP_001920496.1 1160443 D 508767 CDS YP_001920497.1 188588880 6318663 1161068..1161379 1 NC_010723.1 AAA ATPase 1161379 6318663 CLH_1103 Clostridium botulinum E3 str. Alaska E43 AAA ATPase YP_001920497.1 1161068 D 508767 CDS YP_001920498.1 188587629 6318988 1161488..1162720 1 NC_010723.1 hypothetical protein 1162720 6318988 CLH_1104 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920498.1 1161488 D 508767 CDS YP_001920499.1 188590331 6319585 1162731..1165631 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1165631 6319585 CLH_1105 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920499.1 1162731 D 508767 CDS YP_001920500.1 188590413 6317719 1165689..1167392 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1167392 6317719 CLH_1106 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920500.1 1165689 D 508767 CDS YP_001920501.1 188589887 6319373 1167393..1168031 1 NC_010723.1 hypothetical protein 1168031 6319373 CLH_1107 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920501.1 1167393 D 508767 CDS YP_001920502.1 188588213 6318445 1168064..1169308 1 NC_010723.1 identified by match to protein family HMM PF00004; recombination factor protein RarA 1169308 6318445 CLH_1108 Clostridium botulinum E3 str. Alaska E43 recombination factor protein RarA YP_001920502.1 1168064 D 508767 CDS YP_001920503.1 188590647 6319680 complement(1169371..1169592) 1 NC_010723.1 identified by match to protein family HMM PF01381; transcriptional regulator, XRE family 1169592 6319680 CLH_1109 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, XRE family YP_001920503.1 1169371 R 508767 CDS YP_001920504.1 188590132 6319260 complement(1170652..1174410) 1 NC_010723.1 identified by match to protein family HMM PF01742; match to protein family HMM PF07951; match to protein family HMM PF07952; match to protein family HMM PF07953; botulinum neurotoxin, type E3, BoNT/E3 1174410 boNT/E3 6319260 boNT/E3 Clostridium botulinum E3 str. Alaska E43 botulinum neurotoxin, type E3, BoNT/E3 YP_001920504.1 1170652 R 508767 CDS YP_001920505.1 188589186 6317343 complement(1174435..1177926) 1 NC_010723.1 identified by match to protein family HMM PF01742; match to protein family HMM PF07953; match to protein family HMM PF08470; botulinum neurotoxin type E3, nontoxic-nonhemagglutinin component, NTNH 1177926 ntnH 6317343 ntnH Clostridium botulinum E3 str. Alaska E43 botulinum neurotoxin type E3, nontoxic-nonhemagglutinin component, NTNH YP_001920505.1 1174435 R 508767 CDS YP_001920506.1 188587537 6319057 complement(1177942..1179192) 1 NC_010723.1 identified by match to protein family HMM PF06597; P-47 protein 1179192 p47 6319057 p47 Clostridium botulinum E3 str. Alaska E43 P-47 protein YP_001920506.1 1177942 R 508767 CDS YP_001920507.1 188590332 6318615 1179479..1179913 1 NC_010723.1 toxin complex component ORF-X1 1179913 6318615 CLH_1113 Clostridium botulinum E3 str. Alaska E43 toxin complex component ORF-X1 YP_001920507.1 1179479 D 508767 CDS YP_001920508.1 188589416 6317720 1179927..1182173 1 NC_010723.1 toxin complex component ORF-X2 1182173 6317720 CLH_1114 Clostridium botulinum E3 str. Alaska E43 toxin complex component ORF-X2 YP_001920508.1 1179927 D 508767 CDS YP_001920509.1 188588926 6320433 1182205..1183668 1 NC_010723.1 toxin complex component ORF-X3 1183668 6320433 CLH_1115 Clostridium botulinum E3 str. Alaska E43 toxin complex component ORF-X3 YP_001920509.1 1182205 D 508767 CDS YP_001920510.1 188589511 6320412 1184132..1184254 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1184254 6320412 CLH_1116 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920510.1 1184132 D 508767 CDS YP_001920511.1 188590202 6319376 1184255..1184380 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1184380 6319376 CLH_1117 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920511.1 1184255 D 508767 CDS YP_001920512.1 188588096 6317590 1185603..1186367 1 NC_010723.1 AAA ATPase 1186367 6317590 CLH_1118 Clostridium botulinum E3 str. Alaska E43 AAA ATPase YP_001920512.1 1185603 D 508767 CDS YP_001920513.1 188588800 6319215 1186404..1186847 1 NC_010723.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738; Rrf2 family protein 1186847 6319215 CLH_1119 Clostridium botulinum E3 str. Alaska E43 Rrf2 family protein YP_001920513.1 1186404 D 508767 CDS YP_001920514.1 188589493 6319257 1186851..1188032 1 NC_010723.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR03402; cysteine desulfurase NifS 1188032 nifS 6319257 nifS Clostridium botulinum E3 str. Alaska E43 cysteine desulfurase NifS YP_001920514.1 1186851 D 508767 CDS YP_001920515.1 188590610 6318722 1188034..1188471 1 NC_010723.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR03419; FeS cluster assembly scaffold protein NifU 1188471 nifU 6318722 nifU Clostridium botulinum E3 str. Alaska E43 FeS cluster assembly scaffold protein NifU YP_001920515.1 1188034 D 508767 CDS YP_001920516.1 188588033 6319301 1188472..1189557 1 NC_010723.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1189557 mnmA 6319301 mnmA Clostridium botulinum E3 str. Alaska E43 tRNA-specific 2-thiouridylase MnmA YP_001920516.1 1188472 D 508767 CDS YP_001920517.1 188589127 6318247 1189982..1190482 1 NC_010723.1 identified by match to protein family HMM PF05239; PRC-barrel domain-containing protein 1190482 6318247 CLH_1123 Clostridium botulinum E3 str. Alaska E43 PRC-barrel domain-containing protein YP_001920517.1 1189982 D 508767 CDS YP_001920518.1 188589827 6319579 1190460..1191491 1 NC_010723.1 identified by match to protein family HMM PF01594; permease 1191491 6319579 CLH_1124 Clostridium botulinum E3 str. Alaska E43 permease YP_001920518.1 1190460 D 508767 CDS YP_001920519.1 188589293 6317313 1191866..1194505 1 NC_010723.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1194505 alaS 6317313 alaS Clostridium botulinum E3 str. Alaska E43 alanyl-tRNA synthetase YP_001920519.1 1191866 D 508767 CDS YP_001920520.1 188588245 6320515 1194692..1194949 1 NC_010723.1 identified by match to protein family HMM PF06135; hypothetical protein 1194949 6320515 CLH_1126 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920520.1 1194692 D 508767 CDS YP_001920521.1 188587786 6319543 1194998..1195411 1 NC_010723.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1195411 6319543 CLH_1127 Clostridium botulinum E3 str. Alaska E43 Holliday junction resolvase-like protein YP_001920521.1 1194998 D 508767 CDS YP_001920522.1 188588707 6317865 1195624..1195890 1 NC_010723.1 identified by match to protein family HMM PF06949; hypothetical protein 1195890 6317865 CLH_1128 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920522.1 1195624 D 508767 CDS YP_001920523.1 188589907 6319200 1195934..1196398 1 NC_010723.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 1196398 6319200 CLH_1129 Clostridium botulinum E3 str. Alaska E43 Fur family transcriptional regulator YP_001920523.1 1195934 D 508767 CDS YP_001920524.1 188590524 6320534 1196461..1198128 1 NC_010723.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; RNA-metabolising metallo-beta-lactamase family protein 1198128 6320534 CLH_1130 Clostridium botulinum E3 str. Alaska E43 RNA-metabolising metallo-beta-lactamase family protein YP_001920524.1 1196461 D 508767 CDS YP_001920525.1 188588159 6317926 1198323..1200149 1 NC_010723.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA/BipA 1200149 typA 6317926 typA Clostridium botulinum E3 str. Alaska E43 GTP-binding protein TypA/BipA YP_001920525.1 1198323 D 508767 CDS YP_001920526.1 188589035 6318464 1200246..1201274 1 NC_010723.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 1201274 6318464 CLH_1132 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920526.1 1200246 D 508767 CDS YP_001920527.1 188589222 6320369 1201294..1201938 1 NC_010723.1 identified by match to protein family HMM PF01596; match to protein family HMM PF05175; match to protein family HMM PF08241; O-methyltransferase family protein 1201938 6320369 CLH_1133 Clostridium botulinum E3 str. Alaska E43 O-methyltransferase family protein YP_001920527.1 1201294 D 508767 CDS YP_001920528.1 188590162 6317352 1201945..1203180 1 NC_010723.1 identified by match to protein family HMM PF01136; peptidase U32 1203180 6317352 CLH_1134 Clostridium botulinum E3 str. Alaska E43 peptidase U32 YP_001920528.1 1201945 D 508767 CDS YP_001920529.1 188587785 6317777 1203346..1204860 1 NC_010723.1 identified by match to protein family HMM PF00905; penicillin-binding protein 2 1204860 6317777 CLH_1135 Clostridium botulinum E3 str. Alaska E43 penicillin-binding protein 2 YP_001920529.1 1203346 D 508767 CDS YP_001920530.1 188588587 6317864 1204943..1205641 1 NC_010723.1 sigma-28; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell after engulfment; sporulation sigma factor SigK 1205641 sigK 6317864 sigK Clostridium botulinum E3 str. Alaska E43 sporulation sigma factor SigK YP_001920530.1 1204943 D 508767 CDS YP_001920531.1 188589353 6318673 1205810..1206841 1 NC_010723.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching mobility protein 1206841 6318673 CLH_1137 Clostridium botulinum E3 str. Alaska E43 twitching mobility protein YP_001920531.1 1205810 D 508767 CDS YP_001920532.1 188590045 6318293 1206934..1208187 1 NC_010723.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 1208187 ftsA 6318293 ftsA Clostridium botulinum E3 str. Alaska E43 cell division protein FtsA YP_001920532.1 1206934 D 508767 CDS YP_001920533.1 188589878 6317578 1208201..1209343 1 NC_010723.1 identified by match to protein family HMM PF00091; match to protein family HMM PF03953; match to protein family HMM TIGR00065; cell division protein FtsZ 1209343 ftsZ 6317578 ftsZ Clostridium botulinum E3 str. Alaska E43 cell division protein FtsZ YP_001920533.1 1208201 D 508767 CDS YP_001920534.1 188590761 6319306 1209603..1210403 1 NC_010723.1 identified by match to protein family HMM PF03419; match to protein family HMM TIGR02854; sigma-E processing peptidase spoiiga 1210403 spoIIGA 6319306 spoIIGA Clostridium botulinum E3 str. Alaska E43 sigma-E processing peptidase spoiiga YP_001920534.1 1209603 D 508767 CDS YP_001920535.1 188587739 6320164 1210415..1211122 1 NC_010723.1 sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation; sporulation sigma factor SigE 1211122 sigE 6320164 sigE Clostridium botulinum E3 str. Alaska E43 sporulation sigma factor SigE YP_001920535.1 1210415 D 508767 CDS YP_001920536.1 188588400 6319747 1211204..1211977 1 NC_010723.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin; sporulation sigma factor SigG 1211977 sigG 6319747 sigG Clostridium botulinum E3 str. Alaska E43 sporulation sigma factor SigG YP_001920536.1 1211204 D 508767 CDS YP_001920537.1 188589580 6319485 1212256..1212528 1 NC_010723.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888; PRC-barrel domain-containing protein 1212528 6319485 CLH_1143 Clostridium botulinum E3 str. Alaska E43 PRC-barrel domain-containing protein YP_001920537.1 1212256 D 508767 CDS YP_001920538.1 188590304 6319632 1212598..1213050 1 NC_010723.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 1213050 nrdR 6319632 nrdR Clostridium botulinum E3 str. Alaska E43 transcriptional regulator NrdR YP_001920538.1 1212598 D 508767 CDS YP_001920539.1 188588964 6318704 1213283..1213975 1 NC_010723.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 1213975 6318704 CLH_1145 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920539.1 1213283 D 508767 CDS YP_001920540.1 188588892 6319859 1213987..1214691 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 1214691 6319859 CLH_1146 Clostridium botulinum E3 str. Alaska E43 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_001920540.1 1213987 D 508767 CDS YP_001920541.1 188589597 6318419 1214718..1216385 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensory histidine kinase 1216385 6318419 CLH_1147 Clostridium botulinum E3 str. Alaska E43 sensory histidine kinase YP_001920541.1 1214718 D 508767 CDS YP_001920542.1 188590669 6319381 1216669..1217559 1 NC_010723.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136; phosphate-binding protein 1217559 6319381 CLH_1148 Clostridium botulinum E3 str. Alaska E43 phosphate-binding protein YP_001920542.1 1216669 D 508767 CDS YP_001920543.1 188589990 6318794 1217582..1218472 1 NC_010723.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter, permease protein PstC 1218472 pstC 6318794 pstC Clostridium botulinum E3 str. Alaska E43 phosphate ABC transporter, permease protein PstC YP_001920543.1 1217582 D 508767 CDS YP_001920544.1 188590626 6318747 1218472..1219356 1 NC_010723.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter, permease protein PstA 1219356 pstA 6318747 pstA Clostridium botulinum E3 str. Alaska E43 phosphate ABC transporter, permease protein PstA YP_001920544.1 1218472 D 508767 CDS YP_001920545.1 188587749 6318506 1219370..1220119 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00972; phosphate ABC transporter ATP-binding protein 1220119 pstB 6318506 pstB Clostridium botulinum E3 str. Alaska E43 phosphate ABC transporter ATP-binding protein YP_001920545.1 1219370 D 508767 CDS YP_001920546.1 188590563 6318655 1220138..1220794 1 NC_010723.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 1220794 phoU 6318655 phoU Clostridium botulinum E3 str. Alaska E43 phosphate transport system regulatory protein PhoU YP_001920546.1 1220138 D 508767 CDS YP_001920547.1 188590250 6320150 1221016..1222350 1 NC_010723.1 identified by match to protein family HMM PF04459; Fe-S oxidoreductase 1222350 6320150 CLH_1153 Clostridium botulinum E3 str. Alaska E43 Fe-S oxidoreductase YP_001920547.1 1221016 D 508767 CDS YP_001920548.1 188587902 6317742 1222350..1223666 1 NC_010723.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1223666 engA 6317742 engA Clostridium botulinum E3 str. Alaska E43 GTP-binding protein EngA YP_001920548.1 1222350 D 508767 CDS YP_001920549.1 188588511 6317425 1223669..1224661 1 NC_010723.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1224661 gpsA 6317425 gpsA Clostridium botulinum E3 str. Alaska E43 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001920549.1 1223669 D 508767 CDS YP_001920550.1 188589095 6318332 1224810..1226288 1 NC_010723.1 identified by match to protein family HMM PF09547; match to protein family HMM TIGR02836; stage IV sporulation protein A 1226288 spoIVA 6318332 spoIVA Clostridium botulinum E3 str. Alaska E43 stage IV sporulation protein A YP_001920550.1 1224810 D 508767 CDS YP_001920551.1 188590212 6319190 1226448..1226870 1 NC_010723.1 putative plasmid-related protein 1226870 6319190 CLH_1157 Clostridium botulinum E3 str. Alaska E43 putative plasmid-related protein YP_001920551.1 1226448 D 508767 CDS YP_001920552.1 188590521 6317302 1227021..1228010 1 NC_010723.1 identified by match to protein family HMM PF00710; type II L-asparaginase 1228010 ansA 6317302 ansA Clostridium botulinum E3 str. Alaska E43 type II L-asparaginase YP_001920552.1 1227021 D 508767 CDS YP_001920553.1 188590323 6317959 1228305..1229672 1 NC_010723.1 identified by match to protein family HMM PF00860; inner membrane protein YicO 1229672 6317959 CLH_1159 Clostridium botulinum E3 str. Alaska E43 inner membrane protein YicO YP_001920553.1 1228305 D 508767 CDS YP_001920554.1 188589387 6318935 1230074..1230955 1 NC_010723.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255; hypothetical protein 1230955 6318935 CLH_1160 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920554.1 1230074 D 508767 CDS YP_001920555.1 188588532 6318681 1230969..1231238 1 NC_010723.1 identified by match to protein family HMM PF04025; hypothetical protein 1231238 6318681 CLH_1161 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920555.1 1230969 D 508767 CDS YP_001920556.1 188587616 6318375 1231238..1231876 1 NC_010723.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1231876 gmk 6318375 gmk Clostridium botulinum E3 str. Alaska E43 guanylate kinase YP_001920556.1 1231238 D 508767 CDS YP_001920557.1 188590783 6319842 1231857..1232057 1 NC_010723.1 identified by match to protein family HMM PF01192; match to protein family HMM TIGR00690; DNA-directed RNA polymerase subunit omega 1232057 rpoZ 6319842 rpoZ Clostridium botulinum E3 str. Alaska E43 DNA-directed RNA polymerase subunit omega YP_001920557.1 1231857 D 508767 CDS YP_001920558.1 188589673 6319101 1232078..1233256 1 NC_010723.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1233256 coaBC 6319101 coaBC Clostridium botulinum E3 str. Alaska E43 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001920558.1 1232078 D 508767 CDS YP_001920559.1 188588952 6318310 1233320..1235521 1 NC_010723.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1235521 priA 6318310 priA Clostridium botulinum E3 str. Alaska E43 primosome assembly protein PriA YP_001920559.1 1233320 D 508767 CDS YP_001920560.1 188589463 6318416 1235534..1235977 1 NC_010723.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1235977 def 6318416 def Clostridium botulinum E3 str. Alaska E43 peptide deformylase YP_001920560.1 1235534 D 508767 CDS YP_001920561.1 188588955 6320427 1235991..1236920 1 NC_010723.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1236920 fmt 6320427 fmt Clostridium botulinum E3 str. Alaska E43 methionyl-tRNA formyltransferase YP_001920561.1 1235991 D 508767 CDS YP_001920562.1 188587691 6320532 1236961..1237638 1 NC_010723.1 identified by match to protein family HMM PF04298; hypothetical protein 1237638 6320532 CLH_1168 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920562.1 1236961 D 508767 CDS YP_001920563.1 188588047 6318240 1237656..1238972 1 NC_010723.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; ribosomal RNA small subunit methyltransferase B 1238972 sun 6318240 sun Clostridium botulinum E3 str. Alaska E43 ribosomal RNA small subunit methyltransferase B YP_001920563.1 1237656 D 508767 CDS YP_001920564.1 188590485 6319006 1238987..1240030 1 NC_010723.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1240030 6319006 CLH_1170 Clostridium botulinum E3 str. Alaska E43 ribosomal RNA large subunit methyltransferase N YP_001920564.1 1238987 D 508767 CDS YP_001920565.1 188590387 6318881 1240032..1240751 1 NC_010723.1 identified by match to protein family HMM PF00481; protein phosphatase PrpC 1240751 6318881 CLH_1171 Clostridium botulinum E3 str. Alaska E43 protein phosphatase PrpC YP_001920565.1 1240032 D 508767 CDS YP_001920566.1 188589408 6319206 1240753..1242696 1 NC_010723.1 identified by match to protein family HMM PF00069; match to protein family HMM PF03793; match to protein family HMM PF07714; serine/threonine-protein kinase PrkC 1242696 6319206 CLH_1172 Clostridium botulinum E3 str. Alaska E43 serine/threonine-protein kinase PrkC YP_001920566.1 1240753 D 508767 CDS YP_001920567.1 188587599 6319103 1242837..1243709 1 NC_010723.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1243709 rsgA 6319103 rsgA Clostridium botulinum E3 str. Alaska E43 ribosome-associated GTPase YP_001920567.1 1242837 D 508767 CDS YP_001920568.1 188590694 6319689 1243703..1244347 1 NC_010723.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1244347 rpe 6319689 rpe Clostridium botulinum E3 str. Alaska E43 ribulose-phosphate 3-epimerase YP_001920568.1 1243703 D 508767 CDS YP_001920569.1 188589560 6317995 1244356..1244994 1 NC_010723.1 identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378; thiamine pyrophosphokinase 1244994 6317995 CLH_1175 Clostridium botulinum E3 str. Alaska E43 thiamine pyrophosphokinase YP_001920569.1 1244356 D 508767 CDS YP_001920570.1 188590094 6318315 complement(1245256..1245447) 1 NC_010723.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1245447 rpmB 6318315 rpmB Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L28 YP_001920570.1 1245256 R 508767 CDS YP_001920571.1 188589447 6317377 1245645..1245995 1 NC_010723.1 identified by match to protein family HMM PF03780; hypothetical protein 1245995 6317377 CLH_1177 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920571.1 1245645 D 508767 CDS YP_001920572.1 188588512 6319170 1246009..1247655 1 NC_010723.1 identified by match to protein family HMM PF02734; match to protein family HMM TIGR03599; DAK2 domain-containing protein 1247655 6319170 CLH_1178 Clostridium botulinum E3 str. Alaska E43 DAK2 domain-containing protein YP_001920572.1 1246009 D 508767 CDS YP_001920573.1 188588599 6318620 1247721..1249754 1 NC_010723.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1249754 recG 6318620 recG Clostridium botulinum E3 str. Alaska E43 ATP-dependent DNA helicase RecG YP_001920573.1 1247721 D 508767 CDS YP_001920574.1 188587596 6318842 1249817..1250374 1 NC_010723.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095; RNA methyltransferase, RsmD family 1250374 rsmD 6318842 rsmD Clostridium botulinum E3 str. Alaska E43 RNA methyltransferase, RsmD family YP_001920574.1 1249817 D 508767 CDS YP_001920575.1 188590355 6319647 1250377..1250856 1 NC_010723.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1250856 coaD 6319647 coaD Clostridium botulinum E3 str. Alaska E43 phosphopantetheine adenylyltransferase YP_001920575.1 1250377 D 508767 CDS YP_001920576.1 188588860 6317667 1250868..1251410 1 NC_010723.1 archaeal/vacuolar-type H+-ATPase subunit H 1251410 6317667 CLH_1183 Clostridium botulinum E3 str. Alaska E43 archaeal/vacuolar-type H+-ATPase subunit H YP_001920576.1 1250868 D 508767 CDS YP_001920577.1 188589418 6320061 complement(1251390..1252565) 1 NC_010723.1 identified by match to protein family HMM PF07670; match to protein family HMM TIGR02871; sporulation integral membrane protein YlbJ 1252565 ylbJ 6320061 ylbJ Clostridium botulinum E3 str. Alaska E43 sporulation integral membrane protein YlbJ YP_001920577.1 1251390 R 508767 CDS YP_001920578.1 188587995 6320388 complement(1252688..1253884) 1 NC_010723.1 identified by match to protein family HMM PF05636; hypothetical protein 1253884 6320388 CLH_1184 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920578.1 1252688 R 508767 CDS YP_001920579.1 188590010 6317532 1254173..1255171 1 NC_010723.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1255171 eutD 6317532 eutD Clostridium botulinum E3 str. Alaska E43 phosphotransacetylase YP_001920579.1 1254173 D 508767 CDS YP_001920580.1 188587801 6317526 1255197..1256393 1 NC_010723.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1256393 ackA 6317526 ackA Clostridium botulinum E3 str. Alaska E43 acetate kinase YP_001920580.1 1255197 D 508767 CDS YP_001920581.1 188590449 6317891 1256524..1257030 1 NC_010723.1 identified by match to protein family HMM PF02620; hypothetical protein 1257030 6317891 CLH_1187 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920581.1 1256524 D 508767 CDS YP_001920582.1 188589961 6317739 1257033..1257215 1 NC_010723.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1257215 rpmF 6317739 rpmF Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L32 YP_001920582.1 1257033 D 508767 CDS YP_001920583.1 188590682 6319032 1257390..1258391 1 NC_010723.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1258391 plsX 6319032 plsX Clostridium botulinum E3 str. Alaska E43 putative glycerol-3-phosphate acyltransferase PlsX YP_001920583.1 1257390 D 508767 CDS YP_001920584.1 188590044 6317941 1258480..1258710 1 NC_010723.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1258710 acpP 6317941 acpP Clostridium botulinum E3 str. Alaska E43 acyl carrier protein YP_001920584.1 1258480 D 508767 CDS YP_001920585.1 188589361 6320341 1258829..1259527 1 NC_010723.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1259527 rnc 6320341 rnc Clostridium botulinum E3 str. Alaska E43 ribonuclease III YP_001920585.1 1258829 D 508767 CDS YP_001920586.1 188588502 6318103 1259520..1260542 1 NC_010723.1 identified by match to protein family HMM PF04055; radical SAM superfamily protein 1260542 6318103 CLH_1192 Clostridium botulinum E3 str. Alaska E43 radical SAM superfamily protein YP_001920586.1 1259520 D 508767 CDS YP_001920587.1 188590228 6320191 1260830..1264387 1 NC_010723.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR00650; match to protein family HMM TIGR02168; chromosome segregation protein SMC 1264387 smc 6320191 smc Clostridium botulinum E3 str. Alaska E43 chromosome segregation protein SMC YP_001920587.1 1260830 D 508767 CDS YP_001920588.1 188589484 6320470 1264583..1265491 1 NC_010723.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY 1265491 ftsY 6320470 ftsY Clostridium botulinum E3 str. Alaska E43 signal recognition particle-docking protein FtsY YP_001920588.1 1264583 D 508767 CDS YP_001920589.1 188588771 6319229 1265692..1266021 1 NC_010723.1 identified by match to protein family HMM PF04297; match to protein family HMM PF04967; putative DNA-binding protein 1266021 6319229 CLH_1195 Clostridium botulinum E3 str. Alaska E43 putative DNA-binding protein YP_001920589.1 1265692 D 508767 CDS YP_001920590.1 188588867 6319051 1266036..1267394 1 NC_010723.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 1267394 ffh 6319051 ffh Clostridium botulinum E3 str. Alaska E43 signal recognition particle protein YP_001920590.1 1266036 D 508767 CDS YP_001920591.1 188590191 6320581 1267429..1267674 1 NC_010723.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1267674 rpsP 6320581 rpsP Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S16 YP_001920591.1 1267429 D 508767 CDS YP_001920592.1 188587552 6317434 1267724..1267951 1 NC_010723.1 hypothetical protein 1267951 6317434 CLH_1198 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920592.1 1267724 D 508767 CDS YP_001920593.1 188588501 6317930 1268027..1268524 1 NC_010723.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1268524 rimM 6317930 rimM Clostridium botulinum E3 str. Alaska E43 16S rRNA-processing protein RimM YP_001920593.1 1268027 D 508767 CDS YP_001920594.1 188589196 6320461 1268514..1269230 1 NC_010723.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1269230 trmD 6320461 trmD Clostridium botulinum E3 str. Alaska E43 tRNA (guanine-N(1)-)-methyltransferase YP_001920594.1 1268514 D 508767 CDS YP_001920595.1 188590269 6318579 1269353..1269703 1 NC_010723.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1269703 rplS 6318579 rplS Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L19 YP_001920595.1 1269353 D 508767 CDS YP_001920596.1 188588618 6320378 1269817..1270674 1 NC_010723.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1270674 rbgA 6320378 rbgA Clostridium botulinum E3 str. Alaska E43 ribosomal biogenesis GTPase YP_001920596.1 1269817 D 508767 CDS YP_001920597.1 188588936 6317487 1270667..1271482 1 NC_010723.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1271482 rnhB 6317487 rnhB Clostridium botulinum E3 str. Alaska E43 ribonuclease HII YP_001920597.1 1270667 D 508767 CDS YP_001920598.1 188589607 6318960 complement(1271528..1271896) 1 NC_010723.1 identified by match to protein family HMM PF02021; hypothetical protein 1271896 6318960 CLH_1204 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920598.1 1271528 R 508767 CDS YP_001920599.1 188590734 6319002 1272075..1273595 1 NC_010723.1 identified by match to protein family HMM PF01078; match to protein family HMM PF07728; match to protein family HMM TIGR00368; Mg chelatase-like protein 1273595 6319002 CLH_1205 Clostridium botulinum E3 str. Alaska E43 Mg chelatase-like protein YP_001920599.1 1272075 D 508767 CDS YP_001920600.1 188589719 6318811 1273616..1274674 1 NC_010723.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA 1274674 dprA 6318811 dprA Clostridium botulinum E3 str. Alaska E43 DNA protecting protein DprA YP_001920600.1 1273616 D 508767 CDS YP_001920601.1 188590653 6317896 1274725..1276812 1 NC_010723.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1276812 topA 6317896 topA Clostridium botulinum E3 str. Alaska E43 DNA topoisomerase I YP_001920601.1 1274725 D 508767 CDS YP_001920602.1 188587838 6317980 1277003..1277779 1 NC_010723.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1277779 codY 6317980 codY Clostridium botulinum E3 str. Alaska E43 transcriptional repressor CodY YP_001920602.1 1277003 D 508767 CDS YP_001920603.1 188588779 6318818 1278011..1278712 1 NC_010723.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1278712 rpsB 6318818 rpsB Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S2 YP_001920603.1 1278011 D 508767 CDS YP_001920604.1 188589507 6317639 1278895..1279806 1 NC_010723.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1279806 tsf 6317639 tsf Clostridium botulinum E3 str. Alaska E43 elongation factor Ts YP_001920604.1 1278895 D 508767 CDS YP_001920605.1 188590019 6317837 1279915..1280628 1 NC_010723.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1280628 pyrH 6317837 pyrH Clostridium botulinum E3 str. Alaska E43 uridylate kinase YP_001920605.1 1279915 D 508767 CDS YP_001920606.1 188588017 6319663 1280639..1281196 1 NC_010723.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1281196 frr 6319663 frr Clostridium botulinum E3 str. Alaska E43 ribosome recycling factor YP_001920606.1 1280639 D 508767 CDS YP_001920607.1 188588608 6319408 1281295..1282053 1 NC_010723.1 identified by match to protein family HMM PF01255; match to protein family HMM TIGR00055; di-trans,poly-cis-decaprenylcistransferase 1282053 uppS 6319408 uppS Clostridium botulinum E3 str. Alaska E43 di-trans,poly-cis-decaprenylcistransferase YP_001920607.1 1281295 D 508767 CDS YP_001920608.1 188590779 6317347 1282068..1282862 1 NC_010723.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1282862 cdsA 6317347 cdsA Clostridium botulinum E3 str. Alaska E43 phosphatidate cytidylyltransferase YP_001920608.1 1282068 D 508767 CDS YP_001920609.1 188587957 6317860 1283017..1283988 1 NC_010723.1 identified by match to protein family HMM PF01594; hypothetical protein 1283988 6317860 CLH_1215 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920609.1 1283017 D 508767 CDS YP_001920610.1 188589231 6317268 1284039..1285196 1 NC_010723.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1285196 dxr 6317268 dxr Clostridium botulinum E3 str. Alaska E43 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001920610.1 1284039 D 508767 CDS YP_001920611.1 188588698 6320484 1285203..1286231 1 NC_010723.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054; RIP metalloprotease RseP 1286231 rseP 6320484 rseP Clostridium botulinum E3 str. Alaska E43 RIP metalloprotease RseP YP_001920611.1 1285203 D 508767 CDS YP_001920612.1 188587879 6318660 1286243..1287292 1 NC_010723.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1287292 ispG 6318660 ispG Clostridium botulinum E3 str. Alaska E43 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001920612.1 1286243 D 508767 CDS YP_001920613.1 188589600 6317386 1287399..1291757 1 NC_010723.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 1291757 polC 6317386 polC Clostridium botulinum E3 str. Alaska E43 DNA polymerase III PolC YP_001920613.1 1287399 D 508767 CDS YP_001920614.1 188589052 6320197 1292043..1292504 1 NC_010723.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1292504 6320197 CLH_1220 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920614.1 1292043 D 508767 CDS YP_001920615.1 188588167 6320462 1292522..1293676 1 NC_010723.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1293676 nusA 6320462 nusA Clostridium botulinum E3 str. Alaska E43 transcription elongation factor NusA YP_001920615.1 1292522 D 508767 CDS YP_001920616.1 188590695 6319508 1293691..1293957 1 NC_010723.1 identified by match to protein family HMM PF04296; hypothetical protein 1293957 6319508 CLH_1222 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920616.1 1293691 D 508767 CDS YP_001920617.1 188589179 6317996 1293950..1294270 1 NC_010723.1 identified by match to protein family HMM PF01248; ribosomal protein L7Ae family protein 1294270 6317996 CLH_1223 Clostridium botulinum E3 str. Alaska E43 ribosomal protein L7Ae family protein YP_001920617.1 1293950 D 508767 CDS YP_001920618.1 188588635 6317700 1294290..1296353 1 NC_010723.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1296353 infB 6317700 infB Clostridium botulinum E3 str. Alaska E43 translation initiation factor IF-2 YP_001920618.1 1294290 D 508767 CDS YP_001920619.1 188587938 6320075 1296367..1296717 1 NC_010723.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1296717 rbfA 6320075 rbfA Clostridium botulinum E3 str. Alaska E43 ribosome-binding factor A YP_001920619.1 1296367 D 508767 CDS YP_001920620.1 188588632 6317752 1296717..1297694 1 NC_010723.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH subfamily 1 protein 1297694 6317752 CLH_1226 Clostridium botulinum E3 str. Alaska E43 DHH subfamily 1 protein YP_001920620.1 1296717 D 508767 CDS YP_001920621.1 188588310 6317303 1297691..1298566 1 NC_010723.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1298566 truB 6317303 truB Clostridium botulinum E3 str. Alaska E43 tRNA pseudouridine synthase B YP_001920621.1 1297691 D 508767 CDS YP_001920622.1 188590456 6319997 1298583..1299509 1 NC_010723.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1299509 ribF 6319997 ribF Clostridium botulinum E3 str. Alaska E43 bifunctional riboflavin kinase/FMN adenylyltransferase YP_001920622.1 1298583 D 508767 CDS YP_001920623.1 188589191 6317947 1299626..1299889 1 NC_010723.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1299889 rpsO 6317947 rpsO Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S15 YP_001920623.1 1299626 D 508767 CDS YP_001920624.1 188589111 6317287 1299970..1302084 1 NC_010723.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase/polyadenylase 1302084 6317287 CLH_1230 Clostridium botulinum E3 str. Alaska E43 polynucleotide phosphorylase/polyadenylase YP_001920624.1 1299970 D 508767 CDS YP_001920625.1 188588394 6320559 1302363..1303670 1 NC_010723.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family 1303670 6320559 CLH_1231 Clostridium botulinum E3 str. Alaska E43 peptidase, M16 family YP_001920625.1 1302363 D 508767 CDS YP_001920626.1 188587647 6319846 1303741..1304022 1 NC_010723.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888; PRC-barrel domain-containing protein 1304022 6319846 CLH_1232 Clostridium botulinum E3 str. Alaska E43 PRC-barrel domain-containing protein YP_001920626.1 1303741 D 508767 CDS YP_001920627.1 188590234 6319775 1304145..1305344 1 NC_010723.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; aspartate kinase I 1305344 6319775 CLH_1233 Clostridium botulinum E3 str. Alaska E43 aspartate kinase I YP_001920627.1 1304145 D 508767 CDS YP_001920628.1 188589517 6319112 1305410..1306108 1 NC_010723.1 identified by match to protein family HMM PF00574; match to protein family HMM PF01343; Clp protease 1306108 clpP 6319112 clpP Clostridium botulinum E3 str. Alaska E43 Clp protease YP_001920628.1 1305410 D 508767 CDS YP_001920629.1 188588538 6320276 1306227..1308578 1 NC_010723.1 identified by match to protein family HMM PF01580; match to protein family HMM PF09397; DNA translocase FtsK/SpoIIIE 1308578 ftsK 6320276 ftsK Clostridium botulinum E3 str. Alaska E43 DNA translocase FtsK/SpoIIIE YP_001920629.1 1306227 D 508767 CDS YP_001920630.1 188589640 6318719 1308680..1310020 1 NC_010723.1 identified by match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01125; hypothetical protein 1310020 6318719 CLH_1236 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920630.1 1308680 D 508767 CDS YP_001920631.1 188590590 6320093 1310004..1310594 1 NC_010723.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1310594 pgsA 6320093 pgsA Clostridium botulinum E3 str. Alaska E43 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001920631.1 1310004 D 508767 CDS YP_001920632.1 188588142 6320222 1310754..1311824 1 NC_010723.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1311824 recA 6320222 recA Clostridium botulinum E3 str. Alaska E43 recombinase A YP_001920632.1 1310754 D 508767 CDS YP_001920633.1 188589798 6319174 1312139..1313683 1 NC_010723.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1313683 6319174 CLH_1239 Clostridium botulinum E3 str. Alaska E43 phosphodiesterase YP_001920633.1 1312139 D 508767 CDS YP_001920634.1 188590107 6317393 1314072..1314332 1 NC_010723.1 identified by match to protein family HMM PF04232; stage V sporulation protein S 1314332 spoVS 6317393 spoVS Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein S YP_001920634.1 1314072 D 508767 CDS YP_001920635.1 188587539 6317497 1314458..1314718 1 NC_010723.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; HPr family phosphocarrier protein 1314718 6317497 CLH_1241 Clostridium botulinum E3 str. Alaska E43 HPr family phosphocarrier protein YP_001920635.1 1314458 D 508767 CDS YP_001920636.1 188588415 6318617 complement(1314874..1315098) 1 NC_010723.1 identified by match to protein family HMM PF04070; hypothetical protein 1315098 6318617 CLH_1242 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920636.1 1314874 R 508767 CDS YP_001920637.1 188589350 6318830 1315269..1316699 1 NC_010723.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1316699 purB 6318830 purB Clostridium botulinum E3 str. Alaska E43 adenylosuccinate lyase YP_001920637.1 1315269 D 508767 CDS YP_001920638.1 188590277 6318696 complement(1316836..1317819) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1317819 6318696 CLH_1244 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920638.1 1316836 R 508767 CDS YP_001920639.1 188590432 6318156 1318111..1319319 1 NC_010723.1 identified by match to protein family HMM PF00515; hypothetical protein 1319319 6318156 CLH_1245 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920639.1 1318111 D 508767 CDS YP_001920640.1 188589601 6320502 1319786..1320886 1 NC_010723.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 1320886 ribD 6320502 ribD Clostridium botulinum E3 str. Alaska E43 riboflavin biosynthesis protein RibD YP_001920640.1 1319786 D 508767 CDS YP_001920641.1 188587757 6320198 1320901..1321551 1 NC_010723.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1321551 ribE 6320198 ribE Clostridium botulinum E3 str. Alaska E43 riboflavin synthase subunit alpha YP_001920641.1 1320901 D 508767 CDS YP_001920642.1 188588673 6319254 1321718..1322911 1 NC_010723.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506; riboflavin biosynthesis protein ribAB 1322911 6319254 CLH_1248 Clostridium botulinum E3 str. Alaska E43 riboflavin biosynthesis protein ribAB YP_001920642.1 1321718 D 508767 CDS YP_001920643.1 188589177 6318820 1323003..1323464 1 NC_010723.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1323464 ribH 6318820 ribH Clostridium botulinum E3 str. Alaska E43 6,7-dimethyl-8-ribityllumazine synthase YP_001920643.1 1323003 D 508767 CDS YP_001920644.1 188590315 6317944 complement(1323610..1324371) 1 NC_010723.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DNA-binding protein IolR 1324371 6317944 CLH_1250 Clostridium botulinum E3 str. Alaska E43 DNA-binding protein IolR YP_001920644.1 1323610 R 508767 CDS YP_001920645.1 188590267 6320450 1324603..1325757 1 NC_010723.1 identified by match to protein family HMM PF00465; NAD-dependent methanol dehydrogenase 1325757 6320450 CLH_1251 Clostridium botulinum E3 str. Alaska E43 NAD-dependent methanol dehydrogenase YP_001920645.1 1324603 D 508767 CDS YP_001920646.1 188588923 6320376 1325763..1326614 1 NC_010723.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 1326614 6320376 CLH_1252 Clostridium botulinum E3 str. Alaska E43 fructose-bisphosphate aldolase YP_001920646.1 1325763 D 508767 CDS YP_001920647.1 188589989 6318099 1326681..1327700 1 NC_010723.1 identified by match to protein family HMM PF00294; protein IolC 1327700 6318099 CLH_1253 Clostridium botulinum E3 str. Alaska E43 protein IolC YP_001920647.1 1326681 D 508767 CDS YP_001920648.1 188590666 6318746 1327716..1328507 1 NC_010723.1 identified by match to protein family HMM PF06845; myo-inositol catabolism protein IolB 1328507 6318746 CLH_1254 Clostridium botulinum E3 str. Alaska E43 myo-inositol catabolism protein IolB YP_001920648.1 1327716 D 508767 CDS YP_001920649.1 188589155 6320314 1328667..1330598 1 NC_010723.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; malonic semialdehyde oxidative decarboxylase 1330598 6320314 CLH_1255 Clostridium botulinum E3 str. Alaska E43 malonic semialdehyde oxidative decarboxylase YP_001920649.1 1328667 D 508767 CDS YP_001920650.1 188588396 6320188 1330615..1331628 1 NC_010723.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; inositol 2-dehydrogenase 1331628 6320188 CLH_1256 Clostridium botulinum E3 str. Alaska E43 inositol 2-dehydrogenase YP_001920650.1 1330615 D 508767 CDS YP_001920651.1 188590459 6319928 1331724..1332620 1 NC_010723.1 identified by match to protein family HMM PF01261; inosose dehydratase 1332620 6319928 CLH_1257 Clostridium botulinum E3 str. Alaska E43 inosose dehydratase YP_001920651.1 1331724 D 508767 CDS YP_001920652.1 188589695 6320089 1332738..1334330 1 NC_010723.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK 1334330 6320089 CLH_1258 Clostridium botulinum E3 str. Alaska E43 putative symporter YidK YP_001920652.1 1332738 D 508767 CDS YP_001920653.1 188589958 6319674 complement(1334576..1334755) 1 NC_010723.1 hypothetical protein 1334755 6319674 CLH_1259 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920653.1 1334576 R 508767 CDS YP_001920654.1 188588803 6317882 complement(1334920..1336518) 1 NC_010723.1 identified by match to protein family HMM PF07969; exoenzyme regulatory protein AepA 1336518 6317882 CLH_1260 Clostridium botulinum E3 str. Alaska E43 exoenzyme regulatory protein AepA YP_001920654.1 1334920 R 508767 CDS YP_001920655.1 188587668 6320316 1336699..1336935 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1336935 6320316 CLH_1261 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920655.1 1336699 D 508767 CDS YP_001920656.1 188590681 6319397 1337022..1337627 1 NC_010723.1 identified by match to protein family HMM PF00293; nudix-family hydrolase 1337627 6319397 CLH_1262 Clostridium botulinum E3 str. Alaska E43 nudix-family hydrolase YP_001920656.1 1337022 D 508767 CDS YP_001920657.1 188588275 6318495 complement(1337764..1339056) 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; xanthine/uracil permease family protein 1339056 6318495 CLH_1263 Clostridium botulinum E3 str. Alaska E43 xanthine/uracil permease family protein YP_001920657.1 1337764 R 508767 CDS YP_001920658.1 188590787 6319818 1339764..1340327 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1340327 6319818 CLH_1264 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920658.1 1339764 D 508767 CDS YP_001920659.1 188589457 6318160 1340454..1340594 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1340594 6318160 CLH_1265 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920659.1 1340454 D 508767 CDS YP_001920660.1 188588504 6318564 complement(1340975..1342321) 1 NC_010723.1 identified by match to protein family HMM PF00654; voltage-gated chloride channel 1342321 6318564 CLH_1266 Clostridium botulinum E3 str. Alaska E43 voltage-gated chloride channel YP_001920660.1 1340975 R 508767 CDS YP_001920661.1 188590190 6320193 1343484..1344557 1 NC_010723.1 identified by match to protein family HMM PF00465; match to protein family HMM PF01761; glycerol dehydrogenase 1344557 6320193 CLH_1267 Clostridium botulinum E3 str. Alaska E43 glycerol dehydrogenase YP_001920661.1 1343484 D 508767 CDS YP_001920662.1 188589020 6317433 1344643..1345203 1 NC_010723.1 teichoic acid phosphorylcholine esterase 1345203 6317433 CLH_1268 Clostridium botulinum E3 str. Alaska E43 teichoic acid phosphorylcholine esterase YP_001920662.1 1344643 D 508767 CDS YP_001920663.1 188588742 6317647 complement(1345572..1346195) 1 NC_010723.1 hypothetical protein 1346195 6317647 CLH_1269 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920663.1 1345572 R 508767 CDS YP_001920664.1 188587593 6317395 1346547..1348226 1 NC_010723.1 identified by match to protein family HMM PF00682; match to protein family HMM PF08502; match to protein family HMM TIGR00970; 2-isopropylmalate synthase 1348226 leuA 6317395 leuA Clostridium botulinum E3 str. Alaska E43 2-isopropylmalate synthase YP_001920664.1 1346547 D 508767 CDS YP_001920665.1 188590498 6318805 complement(1348514..1349164) 1 NC_010723.1 hypothetical protein 1349164 6318805 CLH_1271 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920665.1 1348514 R 508767 CDS YP_001920666.1 188589409 6319094 1349480..1350337 1 NC_010723.1 identified by match to protein family HMM PF00149; DNA repair exonuclease family protein 1350337 6319094 CLH_1272 Clostridium botulinum E3 str. Alaska E43 DNA repair exonuclease family protein YP_001920666.1 1349480 D 508767 CDS YP_001920667.1 188589043 6319104 1350458..1351933 1 NC_010723.1 identified by match to protein family HMM PF00560; match to protein family HMM PF01473; cell wall binding domain-containing protein 1351933 6319104 CLH_1273 Clostridium botulinum E3 str. Alaska E43 cell wall binding domain-containing protein YP_001920667.1 1350458 D 508767 CDS YP_001920668.1 188588353 6319787 1352192..1353223 1 NC_010723.1 identified by match to protein family HMM PF05343; aminopeptidase, M42 family 1353223 6319787 CLH_1274 Clostridium botulinum E3 str. Alaska E43 aminopeptidase, M42 family YP_001920668.1 1352192 D 508767 CDS YP_001920669.1 188589333 6318892 1353567..1353797 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1353797 6318892 CLH_1275 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920669.1 1353567 D 508767 CDS YP_001920670.1 188589755 6318439 complement(1354075..1355061) 1 NC_010723.1 Fe-S oxidoreductase 1355061 6318439 CLH_1276 Clostridium botulinum E3 str. Alaska E43 Fe-S oxidoreductase YP_001920670.1 1354075 R 508767 CDS YP_001920671.1 188589546 6319389 1355295..1356656 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 1356656 6319389 CLH_1277 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001920671.1 1355295 D 508767 CDS YP_001920672.1 188590308 6317923 complement(1356800..1357189) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1357189 6317923 CLH_1278 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920672.1 1356800 R 508767 CDS YP_001920673.1 188587769 6318699 1357371..1358327 1 NC_010723.1 identified by match to protein family HMM PF02492; cobalamin synthesis protein CobW 1358327 6318699 CLH_1279 Clostridium botulinum E3 str. Alaska E43 cobalamin synthesis protein CobW YP_001920673.1 1357371 D 508767 CDS YP_001920674.1 188588471 6319876 1358342..1358998 1 NC_010723.1 hypothetical protein 1358998 6319876 CLH_1280 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920674.1 1358342 D 508767 CDS YP_001920675.1 188589220 6319136 1359069..1359992 1 NC_010723.1 identified by match to protein family HMM PF03773; transporter 1359992 6319136 CLH_1281 Clostridium botulinum E3 str. Alaska E43 transporter YP_001920675.1 1359069 D 508767 CDS YP_001920676.1 188590705 6317559 complement(1360122..1360520) 1 NC_010723.1 identified by match to protein family HMM PF01814; match to protein family HMM TIGR02481; hemerythrin binding domain-containing protein 1360520 6317559 CLH_1282 Clostridium botulinum E3 str. Alaska E43 hemerythrin binding domain-containing protein YP_001920676.1 1360122 R 508767 CDS YP_001920677.1 188589929 6318405 complement(1360904..1361464) 1 NC_010723.1 putative lipoprotein 1361464 6318405 CLH_1283 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001920677.1 1360904 R 508767 CDS YP_001920678.1 188590641 6319504 complement(1361595..1362503) 1 NC_010723.1 identified by match to protein family HMM PF00892; integral membrane protein domain-containing protein 1362503 6319504 CLH_1284 Clostridium botulinum E3 str. Alaska E43 integral membrane protein domain-containing protein YP_001920678.1 1361595 R 508767 CDS YP_001920679.1 188588101 6320310 1362701..1362910 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1362910 6320310 CLH_1285 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920679.1 1362701 D 508767 CDS YP_001920680.1 188590398 6317969 complement(1363033..1364181) 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase 1364181 6317969 CLH_1286 Clostridium botulinum E3 str. Alaska E43 ATP-dependent RNA helicase YP_001920680.1 1363033 R 508767 CDS YP_001920681.1 188587876 6318001 1364496..1365938 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; match to protein family HMM PF04851; ATP-dependent RNA helicase DbpA 1365938 6318001 CLH_1287 Clostridium botulinum E3 str. Alaska E43 ATP-dependent RNA helicase DbpA YP_001920681.1 1364496 D 508767 CDS YP_001920682.1 188590000 6317735 1366238..1367107 1 NC_010723.1 identified by match to protein family HMM PF00557; match to protein family HMM PF02810; match to protein family HMM TIGR00500; methionine aminopeptidase 1367107 map 6317735 map Clostridium botulinum E3 str. Alaska E43 methionine aminopeptidase YP_001920682.1 1366238 D 508767 CDS YP_001920683.1 188590623 6319788 1367362..1367499 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1367499 6319788 CLH_1289 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920683.1 1367362 D 508767 CDS YP_001920684.1 188589926 6318085 1367673..1369091 1 NC_010723.1 hypothetical protein 1369091 6318085 CLH_1290 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920684.1 1367673 D 508767 CDS YP_001920685.1 188588796 6319493 1369084..1369770 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1369770 6319493 CLH_1291 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920685.1 1369084 D 508767 CDS YP_001920686.1 188588107 6317689 1369772..1372141 1 NC_010723.1 identified by match to protein family HMM PF02463; putative RecF/RecN/SMC N domain 1372141 6317689 CLH_1292 Clostridium botulinum E3 str. Alaska E43 putative RecF/RecN/SMC N domain YP_001920686.1 1369772 D 508767 CDS YP_001920687.1 188590262 6320333 1372304..1372729 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1372729 6320333 CLH_1293 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920687.1 1372304 D 508767 CDS YP_001920688.1 188589544 6317857 1373038..1374993 1 NC_010723.1 hypothetical protein 1374993 6317857 CLH_1294 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920688.1 1373038 D 508767 CDS YP_001920689.1 188590218 6317936 1375077..1375757 1 NC_010723.1 hypothetical protein 1375757 6317936 CLH_1295 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920689.1 1375077 D 508767 CDS YP_001920690.1 188589922 6317620 1376415..1377671 1 NC_010723.1 Zn-dependent hydrolase 1377671 6317620 CLH_1296 Clostridium botulinum E3 str. Alaska E43 Zn-dependent hydrolase YP_001920690.1 1376415 D 508767 CDS YP_001920691.1 188589450 6319395 1377650..1378747 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1378747 6319395 CLH_1297 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920691.1 1377650 D 508767 CDS YP_001920692.1 188589862 6320548 1378751..1379254 1 NC_010723.1 putative lipoprotein 1379254 6320548 CLH_1298 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001920692.1 1378751 D 508767 CDS YP_001920693.1 188588692 6317939 1379256..1381139 1 NC_010723.1 hypothetical protein 1381139 6317939 CLH_1299 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920693.1 1379256 D 508767 CDS YP_001920694.1 188587894 6318667 1381624..1382097 1 NC_010723.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1382097 6318667 CLH_1300 Clostridium botulinum E3 str. Alaska E43 MerR family transcriptional regulator YP_001920694.1 1381624 D 508767 CDS YP_001920695.1 188590009 6317778 1382518..1383327 1 NC_010723.1 MoaF protein 1383327 moaF 6317778 moaF Clostridium botulinum E3 str. Alaska E43 MoaF protein YP_001920695.1 1382518 D 508767 CDS YP_001920696.1 188589323 6317525 1383503..1383625 1 NC_010723.1 transposase and inactivated derivative 1383625 6317525 CLH_1302 Clostridium botulinum E3 str. Alaska E43 transposase and inactivated derivative YP_001920696.1 1383503 D 508767 CDS YP_001920697.1 188588378 6317334 1383757..1383876 1 NC_010723.1 hypothetical protein 1383876 6317334 CLH_1303 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920697.1 1383757 D 508767 CDS YP_001920698.1 188590665 6319759 1384204..1384464 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1384464 6319759 CLH_1304 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920698.1 1384204 D 508767 CDS YP_001920699.1 188590243 6320313 1384579..1384854 1 NC_010723.1 hypothetical protein 1384854 6320313 CLH_1305 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920699.1 1384579 D 508767 CDS YP_001920700.1 188589954 6317338 1384993..1385388 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1385388 6317338 CLH_1306 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920700.1 1384993 D 508767 CDS YP_001920701.1 188590140 6319568 1386210..1386995 1 NC_010723.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein subunit beta 1386995 6319568 CLH_1307 Clostridium botulinum E3 str. Alaska E43 electron transfer flavoprotein subunit beta YP_001920701.1 1386210 D 508767 CDS YP_001920702.1 188587538 6317257 1387017..1387955 1 NC_010723.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein subunit alpha 1387955 6317257 CLH_1308 Clostridium botulinum E3 str. Alaska E43 electron transfer flavoprotein subunit alpha YP_001920702.1 1387017 D 508767 CDS YP_001920703.1 188589256 6318616 1388238..1389788 1 NC_010723.1 identified by match to protein family HMM PF02652; match to protein family HMM PF03600; match to protein family HMM TIGR00795; L-lactate permease 1389788 lctP 6318616 lctP Clostridium botulinum E3 str. Alaska E43 L-lactate permease YP_001920703.1 1388238 D 508767 CDS YP_001920704.1 188589781 6318019 1389943..1391379 1 NC_010723.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidase, FAD-binding 1391379 6318019 CLH_1310 Clostridium botulinum E3 str. Alaska E43 oxidase, FAD-binding YP_001920704.1 1389943 D 508767 CDS YP_001920705.1 188587833 6318064 1391554..1392693 1 NC_010723.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-coa dehydrogenase, short-chain specific 1392693 6318064 CLH_1311 Clostridium botulinum E3 str. Alaska E43 acyl-coa dehydrogenase, short-chain specific YP_001920705.1 1391554 D 508767 CDS YP_001920706.1 188588185 6317261 complement(1392932..1394671) 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1394671 6317261 CLH_1312 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001920706.1 1392932 R 508767 CDS YP_001920707.1 188589113 6319321 1395028..1397220 1 NC_010723.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 1397220 katG 6319321 katG Clostridium botulinum E3 str. Alaska E43 catalase/peroxidase HPI YP_001920707.1 1395028 D 508767 CDS YP_001920708.1 188589246 6320561 1397875..1398852 1 NC_010723.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; PTS system mannose/fructose/sorbose family transporter subunit IIB 1398852 6320561 CLH_1314 Clostridium botulinum E3 str. Alaska E43 PTS system mannose/fructose/sorbose family transporter subunit IIB YP_001920708.1 1397875 D 508767 CDS YP_001920709.1 188588284 6318734 1398888..1399691 1 NC_010723.1 identified by match to protein family HMM PF03609; PTS system sorbose-specific transporter subunit IIC 1399691 6318734 CLH_1315 Clostridium botulinum E3 str. Alaska E43 PTS system sorbose-specific transporter subunit IIC YP_001920709.1 1398888 D 508767 CDS YP_001920710.1 188590537 6319810 1399678..1400622 1 NC_010723.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system mannose/fructose/sorbose family transporter subunit IID 1400622 6319810 CLH_1316 Clostridium botulinum E3 str. Alaska E43 PTS system mannose/fructose/sorbose family transporter subunit IID YP_001920710.1 1399678 D 508767 CDS YP_001920711.1 188589610 6318102 1400829..1401203 1 NC_010723.1 identified by match to protein family HMM PF06115; hypothetical protein 1401203 6318102 CLH_1317 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920711.1 1400829 D 508767 CDS YP_001920712.1 188588726 6319158 1401664..1402458 1 NC_010723.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256; molybdate ABC transporter periplasmic molybdate-binding protein 1402458 modA 6319158 modA Clostridium botulinum E3 str. Alaska E43 molybdate ABC transporter periplasmic molybdate-binding protein YP_001920712.1 1401664 D 508767 CDS YP_001920713.1 188587817 6317679 1402508..1403317 1 NC_010723.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01581; hypothetical protein 1403317 6317679 CLH_1319 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920713.1 1402508 D 508767 CDS YP_001920714.1 188590154 6318390 1403338..1404375 1 NC_010723.1 identified by match to protein family HMM PF00005; spermidine/putrescine import ATP-binding protein PotA 1404375 6318390 CLH_1320 Clostridium botulinum E3 str. Alaska E43 spermidine/putrescine import ATP-binding protein PotA YP_001920714.1 1403338 D 508767 CDS YP_001920715.1 188589272 6317985 1404397..1405131 1 NC_010723.1 hypothetical protein 1405131 6317985 CLH_1321 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920715.1 1404397 D 508767 CDS YP_001920716.1 188589858 6317614 1405442..1406029 1 NC_010723.1 identified by match to protein family HMM PF09335; hypothetical protein 1406029 6317614 CLH_1322 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920716.1 1405442 D 508767 CDS YP_001920717.1 188588518 6317262 1406336..1408081 1 NC_010723.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR01178; adenine deaminase 1408081 ade 6317262 ade Clostridium botulinum E3 str. Alaska E43 adenine deaminase YP_001920717.1 1406336 D 508767 CDS YP_001920718.1 188588087 6317411 complement(1408347..1409936) 1 NC_010723.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 1409936 asnB 6317411 asnB Clostridium botulinum E3 str. Alaska E43 asparagine synthetase B YP_001920718.1 1408347 R 508767 CDS YP_001920719.1 188590768 6318742 complement(1410612..1411934) 1 NC_010723.1 hypothetical protein 1411934 6318742 CLH_1325 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920719.1 1410612 R 508767 CDS YP_001920720.1 188588230 6320241 1412463..1413251 1 NC_010723.1 hypothetical protein 1413251 6320241 CLH_1326 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920720.1 1412463 D 508767 CDS YP_001920721.1 188588905 6319630 1413451..1414890 1 NC_010723.1 identified by match to protein family HMM PF00999; match to protein family HMM PF02080; trk system potassium uptake protein TrkA 1414890 6319630 CLH_1327 Clostridium botulinum E3 str. Alaska E43 trk system potassium uptake protein TrkA YP_001920721.1 1413451 D 508767 CDS YP_001920722.1 188589732 6318365 1415276..1415446 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1415446 6318365 CLH_1328 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920722.1 1415276 D 508767 CDS YP_001920723.1 188590415 6318675 1415600..1417045 1 NC_010723.1 identified by match to protein family HMM PF02366; dolichyl-phosphate-mannose-protein mannosyltransferase 1417045 6318675 CLH_1329 Clostridium botulinum E3 str. Alaska E43 dolichyl-phosphate-mannose-protein mannosyltransferase YP_001920723.1 1415600 D 508767 CDS YP_001920724.1 188588687 6318557 1417237..1417656 1 NC_010723.1 identified by match to protein family HMM PF01047; MarR-family transcriptional regulator 1417656 6318557 CLH_1330 Clostridium botulinum E3 str. Alaska E43 MarR-family transcriptional regulator YP_001920724.1 1417237 D 508767 CDS YP_001920725.1 188589383 6319195 1417656..1419074 1 NC_010723.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; MDR-type permease 1419074 6319195 CLH_1331 Clostridium botulinum E3 str. Alaska E43 MDR-type permease YP_001920725.1 1417656 D 508767 CDS YP_001920726.1 188589378 6318218 1419476..1420441 1 NC_010723.1 identified by match to protein family HMM PF01207; dihydrouridine synthase family protein 1420441 6318218 CLH_1332 Clostridium botulinum E3 str. Alaska E43 dihydrouridine synthase family protein YP_001920726.1 1419476 D 508767 CDS YP_001920727.1 188588560 6317709 1420701..1420895 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1420895 6317709 CLH_1333 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920727.1 1420701 D 508767 CDS YP_001920728.1 188587861 6319564 1421167..1422642 1 NC_010723.1 identified by match to protein family HMM PF02696; hypothetical protein 1422642 6319564 CLH_1334 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920728.1 1421167 D 508767 CDS YP_001920729.1 188590338 6317432 1422826..1423245 1 NC_010723.1 hypothetical protein 1423245 6317432 CLH_1335 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920729.1 1422826 D 508767 CDS YP_001920730.1 188589893 6317989 1423567..1424193 1 NC_010723.1 identified by match to protein family HMM PF09515; thiamine transporter protein 1424193 6317989 CLH_1336 Clostridium botulinum E3 str. Alaska E43 thiamine transporter protein YP_001920730.1 1423567 D 508767 CDS YP_001920731.1 188588430 6318547 1424165..1424818 1 NC_010723.1 identified by match to protein family HMM PF03070; tena/thi-4 family 1424818 6318547 CLH_1337 Clostridium botulinum E3 str. Alaska E43 tena/thi-4 family YP_001920731.1 1424165 D 508767 CDS YP_001920732.1 188590183 6319887 1425211..1426488 1 NC_010723.1 identified by match to protein family HMM PF06354; hypothetical protein 1426488 6319887 CLH_1338 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920732.1 1425211 D 508767 CDS YP_001920733.1 188589029 6318030 1426557..1427309 1 NC_010723.1 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 1427309 6318030 CLH_1339 Clostridium botulinum E3 str. Alaska E43 DnaJ domain-containing protein YP_001920733.1 1426557 D 508767 CDS YP_001920734.1 188588745 6318356 1427685..1428890 1 NC_010723.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1428890 6318356 CLH_1340 Clostridium botulinum E3 str. Alaska E43 major facilitator family transporter YP_001920734.1 1427685 D 508767 CDS YP_001920735.1 188587581 6317460 1429010..1430236 1 NC_010723.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1430236 6317460 CLH_1341 Clostridium botulinum E3 str. Alaska E43 major facilitator family transporter YP_001920735.1 1429010 D 508767 CDS YP_001920736.1 188589048 6318851 1431903..1432631 1 NC_010723.1 identified by match to protein family HMM PF00005; glycine betaine/carnitine/choline transport ATP-binding protein opuCA 1432631 6318851 CLH_1344 Clostridium botulinum E3 str. Alaska E43 glycine betaine/carnitine/choline transport ATP-binding protein opuCA YP_001920736.1 1431903 D 508767 CDS YP_001920737.1 188589260 6319952 1433106..1435421 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; ATPase, P-type 1435421 6319952 CLH_1345 Clostridium botulinum E3 str. Alaska E43 ATPase, P-type YP_001920737.1 1433106 D 508767 CDS YP_001920738.1 188590470 6318769 1436167..1438866 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01524; magnesium-translocating P-type ATPase 1438866 mgtA 6318769 mgtA Clostridium botulinum E3 str. Alaska E43 magnesium-translocating P-type ATPase YP_001920738.1 1436167 D 508767 CDS YP_001920739.1 188588137 6317445 1439347..1440195 1 NC_010723.1 identified by match to protein family HMM PF00753; Zn-dependent hydrolase 1440195 6317445 CLH_1347 Clostridium botulinum E3 str. Alaska E43 Zn-dependent hydrolase YP_001920739.1 1439347 D 508767 CDS YP_001920740.1 188590780 6318573 1440270..1440878 1 NC_010723.1 methyltransferase 1440878 6318573 CLH_1348 Clostridium botulinum E3 str. Alaska E43 methyltransferase YP_001920740.1 1440270 D 508767 CDS YP_001920741.1 188587632 6317861 1441434..1442762 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; xanthine permease 1442762 6317861 CLH_1349 Clostridium botulinum E3 str. Alaska E43 xanthine permease YP_001920741.1 1441434 D 508767 CDS YP_001920742.1 188588929 6319962 1443046..1444956 1 NC_010723.1 identified by match to protein family HMM PF00301; match to protein family HMM PF00441; match to protein family HMM PF00766; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-coA dehydrogenase 1444956 6319962 CLH_1350 Clostridium botulinum E3 str. Alaska E43 acyl-coA dehydrogenase YP_001920742.1 1443046 D 508767 CDS YP_001920743.1 188589799 6318865 1444993..1446192 1 NC_010723.1 identified by match to protein family HMM PF00258; match to protein family HMM PF00753; flavodoxin 1446192 fprA 6318865 fprA Clostridium botulinum E3 str. Alaska E43 flavodoxin YP_001920743.1 1444993 D 508767 CDS YP_001920744.1 188589661 6320145 1446512..1447081 1 NC_010723.1 hypothetical protein 1447081 6320145 CLH_1352 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920744.1 1446512 D 508767 CDS YP_001920745.1 188590578 6320117 1447059..1447508 1 NC_010723.1 hypothetical protein 1447508 6320117 CLH_1353 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920745.1 1447059 D 508767 CDS YP_001920746.1 188588733 6320184 1447511..1448137 1 NC_010723.1 identified by match to protein family HMM PF04647; accessory gene regulator B superfamily 1448137 6320184 CLH_1354 Clostridium botulinum E3 str. Alaska E43 accessory gene regulator B superfamily YP_001920746.1 1447511 D 508767 CDS YP_001920747.1 188589716 6317316 1448173..1448298 1 NC_010723.1 putative autoinducer prepeptide 1448298 6317316 CLH_1355 Clostridium botulinum E3 str. Alaska E43 putative autoinducer prepeptide YP_001920747.1 1448173 D 508767 CDS YP_001920748.1 188588974 6317707 1448354..1450063 1 NC_010723.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01966; match to protein family HMM TIGR00254; ggdef/hd domain protein 1450063 6317707 CLH_1356 Clostridium botulinum E3 str. Alaska E43 ggdef/hd domain protein YP_001920748.1 1448354 D 508767 CDS YP_001920749.1 188588273 6319354 1450501..1451997 1 NC_010723.1 identified by match to protein family HMM PF00324; amino acid permease family protein 1451997 6319354 CLH_1357 Clostridium botulinum E3 str. Alaska E43 amino acid permease family protein YP_001920749.1 1450501 D 508767 CDS YP_001920750.1 188588277 6319816 complement(1452119..1452547) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1452547 6319816 CLH_1358 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920750.1 1452119 R 508767 CDS YP_001920751.1 188589212 6319820 complement(1452672..1453046) 1 NC_010723.1 identified by match to protein family HMM PF00376; transcriptional regulator, MerR family 1453046 6319820 CLH_1359 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, MerR family YP_001920751.1 1452672 R 508767 CDS YP_001920752.1 188588475 6317772 1453232..1454992 1 NC_010723.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; putative 1-deoxy-D-xylulose-5-phosphate synthase 1454992 6317772 CLH_1360 Clostridium botulinum E3 str. Alaska E43 putative 1-deoxy-D-xylulose-5-phosphate synthase YP_001920752.1 1453232 D 508767 CDS YP_001920753.1 188587828 6319219 1455115..1455996 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD-superfamily hydrolase 1455996 6319219 CLH_1361 Clostridium botulinum E3 str. Alaska E43 HAD-superfamily hydrolase YP_001920753.1 1455115 D 508767 CDS YP_001920754.1 188589190 6318467 1456304..1456768 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1456768 6318467 CLH_1362 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920754.1 1456304 D 508767 CDS YP_001920755.1 188588557 6317286 1457063..1458775 1 NC_010723.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00989; match to protein family HMM PF02954; sigma-54-dependent transcriptional regulator YgeV 1458775 6317286 CLH_1363 Clostridium botulinum E3 str. Alaska E43 sigma-54-dependent transcriptional regulator YgeV YP_001920755.1 1457063 D 508767 CDS YP_001920756.1 188587930 6320194 1459101..1460462 1 NC_010723.1 identified by match to protein family HMM PF02667; short-chain fatty acids transporter 1460462 6320194 CLH_1364 Clostridium botulinum E3 str. Alaska E43 short-chain fatty acids transporter YP_001920756.1 1459101 D 508767 CDS YP_001920757.1 188588759 6319023 1460494..1461423 1 NC_010723.1 identified by match to protein family HMM PF00725; match to protein family HMM PF02737; 3-hydroxybutyryl-coa dehydrogenase 1461423 6319023 CLH_1365 Clostridium botulinum E3 str. Alaska E43 3-hydroxybutyryl-coa dehydrogenase YP_001920757.1 1460494 D 508767 CDS YP_001920758.1 188587815 6318979 1461484..1463037 1 NC_010723.1 identified by match to protein family HMM PF01144; propionate CoA-transferase 1463037 6318979 CLH_1366 Clostridium botulinum E3 str. Alaska E43 propionate CoA-transferase YP_001920758.1 1461484 D 508767 CDS YP_001920759.1 188590166 6319797 1463508..1464686 1 NC_010723.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; thermostable carboxypeptidase 1 1464686 6319797 CLH_1367 Clostridium botulinum E3 str. Alaska E43 thermostable carboxypeptidase 1 YP_001920759.1 1463508 D 508767 CDS YP_001920760.1 188588431 6318060 1465097..1466728 1 NC_010723.1 identified by match to protein family HMM PF00728; match to protein family HMM TIGR01634; beta-hexosaminidase 1466728 6318060 CLH_1368 Clostridium botulinum E3 str. Alaska E43 beta-hexosaminidase YP_001920760.1 1465097 D 508767 CDS YP_001920761.1 188588329 6319888 1467025..1468173 1 NC_010723.1 identified by match to protein family HMM PF00465; iron-containing alcohol dehydrogenase 1468173 6319888 CLH_1369 Clostridium botulinum E3 str. Alaska E43 iron-containing alcohol dehydrogenase YP_001920761.1 1467025 D 508767 CDS YP_001920762.1 188590696 6319915 1468441..1469277 1 NC_010723.1 identified by match to protein family HMM PF00376; transcriptional regulatory protein 1469277 6319915 CLH_1370 Clostridium botulinum E3 str. Alaska E43 transcriptional regulatory protein YP_001920762.1 1468441 D 508767 CDS YP_001920763.1 188589782 6318006 1469850..1470947 1 NC_010723.1 membrane spanning protein 1470947 6318006 CLH_1371 Clostridium botulinum E3 str. Alaska E43 membrane spanning protein YP_001920763.1 1469850 D 508767 CDS YP_001920764.1 188590058 6318279 1470947..1471213 1 NC_010723.1 hypothetical protein 1471213 6318279 CLH_1372 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920764.1 1470947 D 508767 CDS YP_001920765.1 188589575 6317803 1471238..1471534 1 NC_010723.1 identified by match to protein family HMM PF00936; microcompartments family protein 1471534 6317803 CLH_1373 Clostridium botulinum E3 str. Alaska E43 microcompartments family protein YP_001920765.1 1471238 D 508767 CDS YP_001920766.1 188588647 6319780 1471561..1471866 1 NC_010723.1 identified by match to protein family HMM PF00936; propanediol utilization protein PduA 1471866 6319780 CLH_1374 Clostridium botulinum E3 str. Alaska E43 propanediol utilization protein PduA YP_001920766.1 1471561 D 508767 CDS YP_001920767.1 188590197 6318917 1471942..1473432 1 NC_010723.1 aldehyde-alcohol dehydrogenase 2 1473432 6318917 CLH_1375 Clostridium botulinum E3 str. Alaska E43 aldehyde-alcohol dehydrogenase 2 YP_001920767.1 1471942 D 508767 CDS YP_001920768.1 188587680 6317714 1473488..1476028 1 NC_010723.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; formate C-acetyltransferase 1476028 6317714 CLH_1376 Clostridium botulinum E3 str. Alaska E43 formate C-acetyltransferase YP_001920768.1 1473488 D 508767 CDS YP_001920769.1 188588547 6318624 1476196..1477149 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating family protein 1477149 6318624 CLH_1377 Clostridium botulinum E3 str. Alaska E43 glycyl-radical enzyme activating family protein YP_001920769.1 1476196 D 508767 CDS YP_001920770.1 188589568 6318324 1477189..1477542 1 NC_010723.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutS-like protein 1477542 6318324 CLH_1378 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization protein EutS-like protein YP_001920770.1 1477189 D 508767 CDS YP_001920771.1 188590205 6319642 1477539..1477979 1 NC_010723.1 GTP-binding protein, EutP/PduV family 1477979 6319642 CLH_1379 Clostridium botulinum E3 str. Alaska E43 GTP-binding protein, EutP/PduV family YP_001920771.1 1477539 D 508767 CDS YP_001920772.1 188587695 6317489 1477997..1478665 1 NC_010723.1 hypothetical protein 1478665 6317489 CLH_1380 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920772.1 1477997 D 508767 CDS YP_001920773.1 188588751 6318221 1478647..1479492 1 NC_010723.1 identified by match to protein family HMM TIGR02529; ethanolamine utilization protein EutJ 1479492 6318221 CLH_1381 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization protein EutJ YP_001920773.1 1478647 D 508767 CDS YP_001920774.1 188589812 6317545 1479508..1479810 1 NC_010723.1 microcompartments protein 1479810 6317545 CLH_1382 Clostridium botulinum E3 str. Alaska E43 microcompartments protein YP_001920774.1 1479508 D 508767 CDS YP_001920775.1 188589327 6317483 1479807..1480070 1 NC_010723.1 identified by match to protein family HMM PF03319; ethanolamine utilization protein EutN/carboxysome structural protein Ccml 1480070 6317483 CLH_1383 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization protein EutN/carboxysome structural protein Ccml YP_001920775.1 1479807 D 508767 CDS YP_001920776.1 188587977 6318879 1480088..1481416 1 NC_010723.1 identified by match to protein family HMM PF01512; respiratory-chain NADH dehydrogenase domain, 51 kda subunit 1481416 6318879 CLH_1384 Clostridium botulinum E3 str. Alaska E43 respiratory-chain NADH dehydrogenase domain, 51 kda subunit YP_001920776.1 1480088 D 508767 CDS YP_001920777.1 188589508 6318234 1481418..1481966 1 NC_010723.1 identified by match to protein family HMM PF00936; microcompartments protein 1481966 6318234 CLH_1385 Clostridium botulinum E3 str. Alaska E43 microcompartments protein YP_001920777.1 1481418 D 508767 CDS YP_001920778.1 188589754 6317838 1482024..1482686 1 NC_010723.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249; transcriptional regulator 1482686 6317838 CLH_1386 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001920778.1 1482024 D 508767 CDS YP_001920779.1 188587821 6319388 1482709..1483467 1 NC_010723.1 identified by match to protein family HMM PF00936; microcompartments family protein 1483467 6319388 CLH_1387 Clostridium botulinum E3 str. Alaska E43 microcompartments family protein YP_001920779.1 1482709 D 508767 CDS YP_001920780.1 188587712 6318857 1483506..1485065 1 NC_010723.1 identified by match to protein family HMM TIGR02518; acetaldehyde dehydrogenase 1485065 6318857 CLH_1388 Clostridium botulinum E3 str. Alaska E43 acetaldehyde dehydrogenase YP_001920780.1 1483506 D 508767 CDS YP_001920781.1 188588414 6317879 1485066..1485716 1 NC_010723.1 identified by match to protein family HMM PF06130; propanediol utilization protein 1485716 6317879 CLH_1389 Clostridium botulinum E3 str. Alaska E43 propanediol utilization protein YP_001920781.1 1485066 D 508767 CDS YP_001920782.1 188588833 6319734 1485773..1486063 1 NC_010723.1 identified by match to protein family HMM PF00936; microcompartments family protein 1486063 6319734 CLH_1390 Clostridium botulinum E3 str. Alaska E43 microcompartments family protein YP_001920782.1 1485773 D 508767 CDS YP_001920783.1 188589984 6319331 1486449..1486838 1 NC_010723.1 identified by match to protein family HMM PF01814; match to protein family HMM TIGR02481; iron-binding protein, hemerythrin 1486838 6319331 CLH_1391 Clostridium botulinum E3 str. Alaska E43 iron-binding protein, hemerythrin YP_001920783.1 1486449 D 508767 CDS YP_001920784.1 188590237 6318186 1487340..1488734 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inner membrane protein YicO 1488734 6318186 CLH_1392 Clostridium botulinum E3 str. Alaska E43 inner membrane protein YicO YP_001920784.1 1487340 D 508767 CDS YP_001920785.1 188588052 6319029 1489151..1490176 1 NC_010723.1 identified by match to protein family HMM PF01497; putative iron chelate uptake ABC transporter solute-binding protein 1490176 6319029 CLH_1393 Clostridium botulinum E3 str. Alaska E43 putative iron chelate uptake ABC transporter solute-binding protein YP_001920785.1 1489151 D 508767 CDS YP_001920786.1 188588381 6319076 1490176..1491258 1 NC_010723.1 identified by match to protein family HMM PF01032; Fe uptake system integral membrane protein 1491258 6319076 CLH_1394 Clostridium botulinum E3 str. Alaska E43 Fe uptake system integral membrane protein YP_001920786.1 1490176 D 508767 CDS YP_001920787.1 188590081 6319940 1491258..1492094 1 NC_010723.1 identified by match to protein family HMM PF00005; iron chelate uptake ABC transporter, FeCT family, ATP-binding protein 1492094 6319940 CLH_1395 Clostridium botulinum E3 str. Alaska E43 iron chelate uptake ABC transporter, FeCT family, ATP-binding protein YP_001920787.1 1491258 D 508767 CDS YP_001920788.1 188587710 6317746 1492184..1492330 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1492330 6317746 CLH_1396 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920788.1 1492184 D 508767 CDS YP_001920789.1 188588593 6319592 complement(1492416..1493519) 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; cold-shock deAd box protein a 1493519 6319592 CLH_1397 Clostridium botulinum E3 str. Alaska E43 cold-shock deAd box protein a YP_001920789.1 1492416 R 508767 CDS YP_001920790.1 188589449 6318633 1494141..1494293 1 NC_010723.1 hypothetical protein 1494293 6318633 CLH_1398 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920790.1 1494141 D 508767 CDS YP_001920791.1 188590557 6320547 1494431..1494583 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1494583 6320547 CLH_1399 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920791.1 1494431 D 508767 CDS YP_001920792.1 188588225 6318504 complement(1494609..1498316) 1 NC_010723.1 identified by match to protein family HMM PF00801; match to protein family HMM PF01752; match to protein family HMM PF04151; match to protein family HMM PF08453; collagenase 1498316 6318504 CLH_1400 Clostridium botulinum E3 str. Alaska E43 collagenase YP_001920792.1 1494609 R 508767 CDS YP_001920793.1 188588980 6319655 1498774..1499961 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1499961 6319655 CLH_1401 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920793.1 1498774 D 508767 CDS YP_001920794.1 188589851 6319341 complement(1500073..1501092) 1 NC_010723.1 identified by match to protein family HMM PF01757; acyltransferase family protein 1501092 6319341 CLH_1402 Clostridium botulinum E3 str. Alaska E43 acyltransferase family protein YP_001920794.1 1500073 R 508767 CDS YP_001920795.1 188590420 6320395 1501315..1502538 1 NC_010723.1 methyltransferase 1502538 6320395 CLH_1403 Clostridium botulinum E3 str. Alaska E43 methyltransferase YP_001920795.1 1501315 D 508767 CDS YP_001920796.1 188590057 6320615 1502798..1504114 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 1504114 6320615 CLH_1404 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001920796.1 1502798 D 508767 CDS YP_001920797.1 188589477 6317802 1504629..1505465 1 NC_010723.1 hypothetical protein 1505465 6317802 CLH_1405 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920797.1 1504629 D 508767 CDS YP_001920798.1 188589622 6317792 1505772..1506062 1 NC_010723.1 identified by match to protein family HMM PF01910; hypothetical protein 1506062 6317792 CLH_1406 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920798.1 1505772 D 508767 CDS YP_001920799.1 188590564 6318731 1506250..1508607 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; diguanylate cyclase/phosphodiesterase domain-containing protein 1508607 6318731 CLH_1407 Clostridium botulinum E3 str. Alaska E43 diguanylate cyclase/phosphodiesterase domain-containing protein YP_001920799.1 1506250 D 508767 CDS YP_001920800.1 188590589 6318789 complement(1508836..1509018) 1 NC_010723.1 hypothetical protein 1509018 6318789 CLH_1408 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920800.1 1508836 R 508767 CDS YP_001920801.1 188587997 6320221 1509259..1509966 1 NC_010723.1 putative F pilin acetylation protein 1509966 6320221 CLH_1409 Clostridium botulinum E3 str. Alaska E43 putative F pilin acetylation protein YP_001920801.1 1509259 D 508767 CDS YP_001920802.1 188589523 6317794 1510267..1510569 1 NC_010723.1 hypothetical protein 1510569 6317794 CLH_1410 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920802.1 1510267 D 508767 CDS YP_001920803.1 188590214 6320285 1510624..1510887 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1510887 6320285 CLH_1411 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920803.1 1510624 D 508767 CDS YP_001920804.1 188588576 6317573 1510977..1511267 1 NC_010723.1 hypothetical protein 1511267 6317573 CLH_1412 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920804.1 1510977 D 508767 CDS YP_001920805.1 188587892 6319199 1511316..1511897 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1511897 6319199 CLH_1413 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920805.1 1511316 D 508767 CDS YP_001920806.1 188587991 6317358 1512034..1513380 1 NC_010723.1 identified by match to protein family HMM PF02056; glycosyl hydrolase family protein 1513380 6317358 CLH_1414 Clostridium botulinum E3 str. Alaska E43 glycosyl hydrolase family protein YP_001920806.1 1512034 D 508767 CDS YP_001920807.1 188587760 6318930 1513699..1516440 1 NC_010723.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; match to protein family HMM PF03610; NtrC family Transcriptional regulator, ATPase domain 1516440 6318930 CLH_1415 Clostridium botulinum E3 str. Alaska E43 NtrC family Transcriptional regulator, ATPase domain YP_001920807.1 1513699 D 508767 CDS YP_001920808.1 188589867 6319973 1516727..1517038 1 NC_010723.1 identified by match to protein family HMM PF02302; PTS system, lactose/cellobiose-specific family, IIB component 1517038 6319973 CLH_1416 Clostridium botulinum E3 str. Alaska E43 PTS system, lactose/cellobiose-specific family, IIB component YP_001920808.1 1516727 D 508767 CDS YP_001920809.1 188589237 6319496 1517061..1517375 1 NC_010723.1 identified by match to protein family HMM PF02255; PTS system lactose/cellobiose-specific transporter subunit IIA 1517375 6319496 CLH_1417 Clostridium botulinum E3 str. Alaska E43 PTS system lactose/cellobiose-specific transporter subunit IIA YP_001920809.1 1517061 D 508767 CDS YP_001920810.1 188588849 6318984 1517457..1518191 1 NC_010723.1 identified by match to protein family HMM PF01869; ATPase family protein 1518191 6318984 CLH_1418 Clostridium botulinum E3 str. Alaska E43 ATPase family protein YP_001920810.1 1517457 D 508767 CDS YP_001920811.1 188587913 6318632 1518332..1519441 1 NC_010723.1 identified by match to protein family HMM PF05913; outer surface protein 1519441 6318632 CLH_1419 Clostridium botulinum E3 str. Alaska E43 outer surface protein YP_001920811.1 1518332 D 508767 CDS YP_001920812.1 188590278 6318264 1519488..1520756 1 NC_010723.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system, lactose/cellobiose family IIC component 1520756 6318264 CLH_1420 Clostridium botulinum E3 str. Alaska E43 PTS system, lactose/cellobiose family IIC component YP_001920812.1 1519488 D 508767 CDS YP_001920813.1 188589178 6318157 1521147..1521953 1 NC_010723.1 identified by match to protein family HMM PF02588; membrane protein 1521953 6318157 CLH_1421 Clostridium botulinum E3 str. Alaska E43 membrane protein YP_001920813.1 1521147 D 508767 CDS YP_001920814.1 188589200 6317945 1522017..1522664 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two-component response regulator 1522664 6317945 CLH_1422 Clostridium botulinum E3 str. Alaska E43 two-component response regulator YP_001920814.1 1522017 D 508767 CDS YP_001920815.1 188588328 6317622 1522654..1524027 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 1524027 6317622 CLH_1423 Clostridium botulinum E3 str. Alaska E43 sensor histidine kinase YP_001920815.1 1522654 D 508767 CDS YP_001920816.1 188590693 6319919 1524063..1526369 1 NC_010723.1 putative lipoprotein 1526369 6319919 CLH_1424 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001920816.1 1524063 D 508767 CDS YP_001920817.1 188588370 6317994 1526845..1529370 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; ATPase, P-type 1529370 6317994 CLH_1425 Clostridium botulinum E3 str. Alaska E43 ATPase, P-type YP_001920817.1 1526845 D 508767 CDS YP_001920818.1 188589282 6319978 1529638..1530090 1 NC_010723.1 identified by match to protein family HMM PF00583; spermine/spermidine acetyltransferase 1530090 6319978 CLH_1426 Clostridium botulinum E3 str. Alaska E43 spermine/spermidine acetyltransferase YP_001920818.1 1529638 D 508767 CDS YP_001920819.1 188589425 6317723 complement(1530387..1531724) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 1531724 6317723 CLH_1427 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001920819.1 1530387 R 508767 CDS YP_001920820.1 188590343 6317610 complement(1532088..1532234) 1 NC_010723.1 hypothetical protein 1532234 6317610 CLH_1428 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920820.1 1532088 R 508767 CDS YP_001920821.1 188590607 6318908 1532556..1534436 1 NC_010723.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995; PTS system beta-glucoside-specific transporter subunit IIABC 1534436 6318908 CLH_1429 Clostridium botulinum E3 str. Alaska E43 PTS system beta-glucoside-specific transporter subunit IIABC YP_001920821.1 1532556 D 508767 CDS YP_001920822.1 188588218 6318498 1534525..1535937 1 NC_010723.1 identified by match to protein family HMM PF00232; beta-glucosidase 1535937 6318498 CLH_1430 Clostridium botulinum E3 str. Alaska E43 beta-glucosidase YP_001920822.1 1534525 D 508767 CDS YP_001920823.1 188589860 6319677 1535977..1536810 1 NC_010723.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LicT 1536810 6319677 CLH_1431 Clostridium botulinum E3 str. Alaska E43 transcription antiterminator LicT YP_001920823.1 1535977 D 508767 CDS YP_001920824.1 188590778 6317264 1537291..1537488 1 NC_010723.1 hypothetical protein 1537488 6317264 CLH_1432 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920824.1 1537291 D 508767 CDS YP_001920825.1 188587585 6317859 1537659..1538306 1 NC_010723.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460; nitrite reductase 1538306 6317859 CLH_1433 Clostridium botulinum E3 str. Alaska E43 nitrite reductase YP_001920825.1 1537659 D 508767 CDS YP_001920826.1 188588494 6318195 1538597..1538842 1 NC_010723.1 identified by match to protein family HMM PF08281; ECF subfamily RNA polymerase sigma-70 factor 1538842 6318195 CLH_1434 Clostridium botulinum E3 str. Alaska E43 ECF subfamily RNA polymerase sigma-70 factor YP_001920826.1 1538597 D 508767 CDS YP_001920827.1 188588368 6320258 1538823..1539785 1 NC_010723.1 hypothetical protein 1539785 6320258 CLH_1435 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920827.1 1538823 D 508767 CDS YP_001920828.1 188588144 6319523 1540046..1540867 1 NC_010723.1 identified by match to protein family HMM PF00015; putative methyl-accepting chemotaxis protein 1540867 6319523 CLH_1436 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis protein YP_001920828.1 1540046 D 508767 CDS YP_001920829.1 188590145 6317893 1541171..1541941 1 NC_010723.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 1541941 6317893 CLH_1437 Clostridium botulinum E3 str. Alaska E43 polysaccharide deacetylase family protein YP_001920829.1 1541171 D 508767 CDS YP_001920830.1 188589280 6317641 complement(1541992..1542303) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1542303 6317641 CLH_1438 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920830.1 1541992 R 508767 CDS YP_001920831.1 188587960 6317597 1542567..1543496 1 NC_010723.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR02152; ribokinase 1543496 rbsK 6317597 rbsK Clostridium botulinum E3 str. Alaska E43 ribokinase YP_001920831.1 1542567 D 508767 CDS YP_001920832.1 188587860 6317298 1543502..1543897 1 NC_010723.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 1543897 6317298 CLH_1440 Clostridium botulinum E3 str. Alaska E43 D-ribose pyranase YP_001920832.1 1543502 D 508767 CDS YP_001920833.1 188589814 6317431 1543912..1545414 1 NC_010723.1 identified by match to protein family HMM PF00005; ribose import ATP-binding protein RbsA 1545414 6317431 CLH_1441 Clostridium botulinum E3 str. Alaska E43 ribose import ATP-binding protein RbsA YP_001920833.1 1543912 D 508767 CDS YP_001920834.1 188588927 6320026 1545431..1546366 1 NC_010723.1 identified by match to protein family HMM PF02653; ribose transport system permease RbsC 1546366 6320026 CLH_1442 Clostridium botulinum E3 str. Alaska E43 ribose transport system permease RbsC YP_001920834.1 1545431 D 508767 CDS YP_001920835.1 188587584 6320413 1546391..1547293 1 NC_010723.1 identified by match to protein family HMM PF00532; D-ribose-binding protein 1547293 6320413 CLH_1443 Clostridium botulinum E3 str. Alaska E43 D-ribose-binding protein YP_001920835.1 1546391 D 508767 CDS YP_001920836.1 188590161 6318194 1547345..1548340 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator, LacI family 1548340 6318194 CLH_1444 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, LacI family YP_001920836.1 1547345 D 508767 CDS YP_001920837.1 188590587 6317776 complement(1548573..1549001) 1 NC_010723.1 identified by match to protein family HMM PF06094; hypothetical protein 1549001 6317776 CLH_1445 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920837.1 1548573 R 508767 CDS YP_001920838.1 188588224 6320219 complement(1549001..1549642) 1 NC_010723.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 1549642 pcp 6320219 pcp Clostridium botulinum E3 str. Alaska E43 pyrrolidone-carboxylate peptidase YP_001920838.1 1549001 R 508767 CDS YP_001920839.1 188589634 6319654 complement(1550117..1551046) 1 NC_010723.1 identified by match to protein family HMM PF06166; permease 1551046 6319654 CLH_1447 Clostridium botulinum E3 str. Alaska E43 permease YP_001920839.1 1550117 R 508767 CDS YP_001920840.1 188590588 6318474 complement(1551065..1551736) 1 NC_010723.1 identified by match to protein family HMM PF06149; permease 1551736 6318474 CLH_1448 Clostridium botulinum E3 str. Alaska E43 permease YP_001920840.1 1551065 R 508767 CDS YP_001920841.1 188590569 6320220 1552125..1553114 1 NC_010723.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; NAD-dependent epimerase/dehydratase 1553114 6320220 CLH_1449 Clostridium botulinum E3 str. Alaska E43 NAD-dependent epimerase/dehydratase YP_001920841.1 1552125 D 508767 CDS YP_001920842.1 188589628 6320230 1553314..1554483 1 NC_010723.1 identified by match to protein family HMM PF01041; DegT/DnrJ/EryC1/StrS aminotransferase 1554483 6320230 CLH_1450 Clostridium botulinum E3 str. Alaska E43 DegT/DnrJ/EryC1/StrS aminotransferase YP_001920842.1 1553314 D 508767 CDS YP_001920843.1 188590117 6318541 1554750..1555457 1 NC_010723.1 identified by match to protein family HMM PF02348; N-acylneuraminate cytidylyltransferase 1555457 6318541 CLH_1451 Clostridium botulinum E3 str. Alaska E43 N-acylneuraminate cytidylyltransferase YP_001920843.1 1554750 D 508767 CDS YP_001920844.1 188587756 6317265 1555450..1556592 1 NC_010723.1 hypothetical protein 1556592 6317265 CLH_1452 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920844.1 1555450 D 508767 CDS YP_001920845.1 188588168 6319090 1556851..1557873 1 NC_010723.1 hypothetical protein 1557873 6319090 CLH_1453 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920845.1 1556851 D 508767 CDS YP_001920846.1 188589079 6319509 1558010..1558315 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1558315 6319509 CLH_1454 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920846.1 1558010 D 508767 CDS YP_001920847.1 188587592 6318461 1558523..1558855 1 NC_010723.1 hypothetical protein 1558855 6318461 CLH_1455 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920847.1 1558523 D 508767 CDS YP_001920848.1 188588503 6318804 1558954..1560678 1 NC_010723.1 identified by match to protein family HMM PF01973; hypothetical protein 1560678 6318804 CLH_1456 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920848.1 1558954 D 508767 CDS YP_001920849.1 188589672 6320192 1560767..1560961 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1560961 6320192 CLH_1457 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920849.1 1560767 D 508767 CDS YP_001920850.1 188590602 6318309 1560973..1561278 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1561278 6318309 CLH_1458 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920850.1 1560973 D 508767 CDS YP_001920851.1 188588263 6319313 1561297..1561605 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1561605 6319313 CLH_1459 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920851.1 1561297 D 508767 CDS YP_001920852.1 188589199 6319857 1561643..1561933 1 NC_010723.1 hypothetical protein 1561933 6319857 CLH_1460 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920852.1 1561643 D 508767 CDS YP_001920853.1 188590170 6317621 1562005..1563048 1 NC_010723.1 identified by match to protein family HMM PF00483; match to protein family HMM PF00571; nucleotidyl transferase 1563048 6317621 CLH_1461 Clostridium botulinum E3 str. Alaska E43 nucleotidyl transferase YP_001920853.1 1562005 D 508767 CDS YP_001920854.1 188587745 6318840 complement(1563313..1563822) 1 NC_010723.1 identified by match to protein family HMM PF00583; putative acetyltransferase 1563822 6318840 CLH_1462 Clostridium botulinum E3 str. Alaska E43 putative acetyltransferase YP_001920854.1 1563313 R 508767 CDS YP_001920855.1 188588651 6319763 1564020..1565165 1 NC_010723.1 identified by match to protein family HMM PF02350; UDP-N-acetylglucosamine 2-epimerase 1565165 6319763 CLH_1463 Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylglucosamine 2-epimerase YP_001920855.1 1564020 D 508767 CDS YP_001920856.1 188589612 6317371 1565155..1565829 1 NC_010723.1 identified by match to protein family HMM PF02585; GlcNAc-PI de-N-acetylase family 1565829 6317371 CLH_1464 Clostridium botulinum E3 str. Alaska E43 GlcNAc-PI de-N-acetylase family YP_001920856.1 1565155 D 508767 CDS YP_001920857.1 188589937 6319160 1565842..1566795 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1566795 6319160 CLH_1465 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920857.1 1565842 D 508767 CDS YP_001920858.1 188590640 6319939 1566834..1567838 1 NC_010723.1 identified by match to protein family HMM PF03102; match to protein family HMM PF08666; spore coat polysaccharide biosynthesis protein SpsE 1567838 6319939 CLH_1466 Clostridium botulinum E3 str. Alaska E43 spore coat polysaccharide biosynthesis protein SpsE YP_001920858.1 1566834 D 508767 CDS YP_001920859.1 188588610 6317922 complement(1567985..1568440) 1 NC_010723.1 identified by match to protein family HMM PF04657; hypothetical protein 1568440 6317922 CLH_1467 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920859.1 1567985 R 508767 CDS YP_001920860.1 188587989 6320355 complement(1568459..1568881) 1 NC_010723.1 hypothetical protein 1568881 6320355 CLH_1468 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920860.1 1568459 R 508767 CDS YP_001920861.1 188590532 6318928 1569043..1569405 1 NC_010723.1 hypothetical protein 1569405 6318928 CLH_1469 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920861.1 1569043 D 508767 CDS YP_001920862.1 188589810 6320244 1569689..1570375 1 NC_010723.1 identified by match to protein family HMM PF00027; cNMP-binding regulatory protein 1570375 6320244 CLH_1470 Clostridium botulinum E3 str. Alaska E43 cNMP-binding regulatory protein YP_001920862.1 1569689 D 508767 CDS YP_001920863.1 188589047 6317481 complement(1570437..1571396) 1 NC_010723.1 identified by match to protein family HMM PF01699; putative cation antiporter 1571396 6317481 CLH_1471 Clostridium botulinum E3 str. Alaska E43 putative cation antiporter YP_001920863.1 1570437 R 508767 CDS YP_001920864.1 188588298 6319951 1571986..1572852 1 NC_010723.1 identified by match to protein family HMM PF04055; oxygen-independent coproporphyrinogen III oxidase, Fe-S oxidoreductase 1572852 6319951 CLH_1472 Clostridium botulinum E3 str. Alaska E43 oxygen-independent coproporphyrinogen III oxidase, Fe-S oxidoreductase YP_001920864.1 1571986 D 508767 CDS YP_001920865.1 188589257 6319911 1572879..1573166 1 NC_010723.1 identified by match to protein family HMM PF03992; antibiotic biosynthesis monooxygenase 1573166 6319911 CLH_1473 Clostridium botulinum E3 str. Alaska E43 antibiotic biosynthesis monooxygenase YP_001920865.1 1572879 D 508767 CDS YP_001920866.1 188588565 6318020 1573498..1574403 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01584; chemotaxis protein CheV 1574403 6318020 CLH_1474 Clostridium botulinum E3 str. Alaska E43 chemotaxis protein CheV YP_001920866.1 1573498 D 508767 CDS YP_001920867.1 188588429 6318412 1574734..1575909 1 NC_010723.1 methyltransferase 1575909 6318412 CLH_1475 Clostridium botulinum E3 str. Alaska E43 methyltransferase YP_001920867.1 1574734 D 508767 CDS YP_001920868.1 188587743 6319283 1576108..1576650 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1576650 6319283 CLH_1476 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920868.1 1576108 D 508767 CDS YP_001920869.1 188590767 6319852 complement(1576904..1577050) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1577050 6319852 CLH_1477 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920869.1 1576904 R 508767 CDS YP_001920870.1 188588407 6320240 complement(1577144..1577995) 1 NC_010723.1 identified by match to protein family HMM PF00165; match to protein family HMM PF07883; AraC-type DNA-binding domain-containing protein, transcriptional regulator 1577995 6320240 CLH_1478 Clostridium botulinum E3 str. Alaska E43 AraC-type DNA-binding domain-containing protein, transcriptional regulator YP_001920870.1 1577144 R 508767 CDS YP_001920871.1 188588917 6319664 1578001..1578126 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1578126 6319664 CLH_1479 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920871.1 1578001 D 508767 CDS YP_001920872.1 188588095 6319326 1578195..1579427 1 NC_010723.1 identified by match to protein family HMM PF00375; H+/sodium:glutamate symporter 1579427 6319326 CLH_1480 Clostridium botulinum E3 str. Alaska E43 H+/sodium:glutamate symporter YP_001920872.1 1578195 D 508767 CDS YP_001920873.1 188590463 6318216 1579558..1580373 1 NC_010723.1 identified by match to protein family HMM PF04607; GTP pyrophosphokinase 1580373 6318216 CLH_1481 Clostridium botulinum E3 str. Alaska E43 GTP pyrophosphokinase YP_001920873.1 1579558 D 508767 CDS YP_001920874.1 188587886 6320261 1580601..1581686 1 NC_010723.1 identified by match to protein family HMM PF01966; HD-GYP hydrolase domain containing protein 1581686 6320261 CLH_1482 Clostridium botulinum E3 str. Alaska E43 HD-GYP hydrolase domain containing protein YP_001920874.1 1580601 D 508767 CDS YP_001920875.1 188589064 6319340 1581932..1582804 1 NC_010723.1 identified by match to protein family HMM PF03446; 2-hydroxy-3-oxopropionate reductase 1582804 6319340 CLH_1483 Clostridium botulinum E3 str. Alaska E43 2-hydroxy-3-oxopropionate reductase YP_001920875.1 1581932 D 508767 CDS YP_001920876.1 188589758 6320233 complement(1583031..1584038) 1 NC_010723.1 identified by match to protein family HMM PF00291; cysteine synthase 1584038 6320233 CLH_1484 Clostridium botulinum E3 str. Alaska E43 cysteine synthase YP_001920876.1 1583031 R 508767 CDS YP_001920877.1 188588757 6318568 1584463..1585851 1 NC_010723.1 hypothetical protein 1585851 6318568 CLH_1485 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920877.1 1584463 D 508767 CDS YP_001920878.1 188590505 6318202 complement(1586031..1587191) 1 NC_010723.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1587191 alr 6318202 alr Clostridium botulinum E3 str. Alaska E43 alanine racemase YP_001920878.1 1586031 R 508767 CDS YP_001920879.1 188588077 6317999 complement(1587313..1588773) 1 NC_010723.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR-family transcriptional regulator 1588773 6317999 CLH_1487 Clostridium botulinum E3 str. Alaska E43 GntR-family transcriptional regulator YP_001920879.1 1587313 R 508767 CDS YP_001920880.1 188589131 6320268 1589044..1590426 1 NC_010723.1 hypothetical protein 1590426 6320268 CLH_1488 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920880.1 1589044 D 508767 CDS YP_001920881.1 188589284 6319960 1590560..1590847 1 NC_010723.1 identified by match to protein family HMM PF04456; hypothetical protein 1590847 6319960 CLH_1489 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920881.1 1590560 D 508767 CDS YP_001920882.1 188590095 6317427 1590863..1591819 1 NC_010723.1 identified by match to protein family HMM PF06081; membrane spanning protein 1591819 6317427 CLH_1490 Clostridium botulinum E3 str. Alaska E43 membrane spanning protein YP_001920882.1 1590863 D 508767 CDS YP_001920883.1 188587945 6317378 1591962..1592480 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1592480 6317378 CLH_1491 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920883.1 1591962 D 508767 CDS YP_001920884.1 188588660 6320551 complement(1592658..1593392) 1 NC_010723.1 identified by match to protein family HMM PF00392; transcriptional regulatory protein 1593392 6320551 CLH_1492 Clostridium botulinum E3 str. Alaska E43 transcriptional regulatory protein YP_001920884.1 1592658 R 508767 CDS YP_001920885.1 188590637 6318077 1594058..1594840 1 NC_010723.1 identified by match to protein family HMM PF01048; match to protein family HMM TIGR01718; uridine phosphorylase 1594840 udp 6318077 udp Clostridium botulinum E3 str. Alaska E43 uridine phosphorylase YP_001920885.1 1594058 D 508767 CDS YP_001920886.1 188588057 6318151 1595026..1596228 1 NC_010723.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; nucleoside permease NupC 1596228 6318151 CLH_1494 Clostridium botulinum E3 str. Alaska E43 nucleoside permease NupC YP_001920886.1 1595026 D 508767 CDS YP_001920887.1 188588364 6318371 1596411..1597601 1 NC_010723.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1597601 deoB 6318371 deoB Clostridium botulinum E3 str. Alaska E43 phosphopentomutase YP_001920887.1 1596411 D 508767 CDS YP_001920888.1 188587675 6320013 1597826..1598641 1 NC_010723.1 identified by match to protein family HMM PF00456; transketolase 1598641 6320013 CLH_1496 Clostridium botulinum E3 str. Alaska E43 transketolase YP_001920888.1 1597826 D 508767 CDS YP_001920889.1 188589778 6318127 1598654..1599580 1 NC_010723.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase 1599580 6318127 CLH_1497 Clostridium botulinum E3 str. Alaska E43 transketolase YP_001920889.1 1598654 D 508767 CDS YP_001920890.1 188590475 6320421 1599653..1600360 1 NC_010723.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 1600360 deoD 6320421 deoD Clostridium botulinum E3 str. Alaska E43 purine nucleoside phosphorylase YP_001920890.1 1599653 D 508767 CDS YP_001920891.1 188588326 6319701 1600537..1601181 1 NC_010723.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00875; putative transaldolase 1601181 6319701 CLH_1499 Clostridium botulinum E3 str. Alaska E43 putative transaldolase YP_001920891.1 1600537 D 508767 CDS YP_001920892.1 188589018 6319917 1601707..1603857 1 NC_010723.1 identified by match to protein family HMM TIGR03061; match to protein family HMM TIGR03062; phage infection protein 1603857 6319917 CLH_1500 Clostridium botulinum E3 str. Alaska E43 phage infection protein YP_001920892.1 1601707 D 508767 CDS YP_001920893.1 188589292 6319179 1604226..1604540 1 NC_010723.1 hypothetical protein 1604540 6319179 CLH_1501 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920893.1 1604226 D 508767 CDS YP_001920894.1 188590083 6320514 complement(1604781..1606154) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; Na+-driven multidrug efflux pump 1606154 6320514 CLH_1502 Clostridium botulinum E3 str. Alaska E43 Na+-driven multidrug efflux pump YP_001920894.1 1604781 R 508767 CDS YP_001920895.1 188587868 6317281 1606584..1608248 1 NC_010723.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; metallo-beta-lactamase superfamily protein 1608248 6317281 CLH_1503 Clostridium botulinum E3 str. Alaska E43 metallo-beta-lactamase superfamily protein YP_001920895.1 1606584 D 508767 CDS YP_001920896.1 188588662 6319609 1608738..1611245 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1611245 6319609 CLH_1504 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920896.1 1608738 D 508767 CDS YP_001920897.1 188590165 6317534 1611273..1612031 1 NC_010723.1 putative viral A-type inclusion protein 1612031 6317534 CLH_1505 Clostridium botulinum E3 str. Alaska E43 putative viral A-type inclusion protein YP_001920897.1 1611273 D 508767 CDS YP_001920898.1 188587588 6318059 1612038..1613807 1 NC_010723.1 hypothetical protein 1613807 6318059 CLH_1506 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920898.1 1612038 D 508767 CDS YP_001920899.1 188590340 6318807 1613844..1615646 1 NC_010723.1 identified by match to protein family HMM PF01926; putative GTPase 1615646 6318807 CLH_1507 Clostridium botulinum E3 str. Alaska E43 putative GTPase YP_001920899.1 1613844 D 508767 CDS YP_001920900.1 188587798 6318773 1616159..1617343 1 NC_010723.1 identified by match to protein family HMM PF01041; spore coat polysaccharide biosynthesis protein SpsC 1617343 6318773 CLH_1508 Clostridium botulinum E3 str. Alaska E43 spore coat polysaccharide biosynthesis protein SpsC YP_001920900.1 1616159 D 508767 CDS YP_001920901.1 188589737 6319447 1617953..1619113 1 NC_010723.1 identified by match to protein family HMM PF00376; match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; transcriptional regulator 1619113 6319447 CLH_1509 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001920901.1 1617953 D 508767 CDS YP_001920902.1 188590412 6318320 1619306..1619665 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1619665 6318320 CLH_1510 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920902.1 1619306 D 508767 CDS YP_001920903.1 188588276 6319372 1619780..1619962 1 NC_010723.1 TrpF 1619962 6319372 CLH_1511 Clostridium botulinum E3 str. Alaska E43 TrpF YP_001920903.1 1619780 D 508767 CDS YP_001920904.1 188588986 6319819 1620160..1620699 1 NC_010723.1 amidase 1620699 6319819 CLH_1512 Clostridium botulinum E3 str. Alaska E43 amidase YP_001920904.1 1620160 D 508767 CDS YP_001920905.1 188589312 6318337 complement(1620927..1621742) 1 NC_010723.1 putative viral A-type inclusion protein 1621742 6318337 CLH_1513 Clostridium botulinum E3 str. Alaska E43 putative viral A-type inclusion protein YP_001920905.1 1620927 R 508767 CDS YP_001920906.1 188590067 6317561 1621913..1623739 1 NC_010723.1 identified by match to protein family HMM PF00082; putative spore-cortex-lytic enzyme 1623739 6317561 CLH_1514 Clostridium botulinum E3 str. Alaska E43 putative spore-cortex-lytic enzyme YP_001920906.1 1621913 D 508767 CDS YP_001920907.1 188589914 6320366 1623726..1625447 1 NC_010723.1 identified by match to protein family HMM PF00082; putative spore-cortex-lytic enzyme 1625447 6320366 CLH_1515 Clostridium botulinum E3 str. Alaska E43 putative spore-cortex-lytic enzyme YP_001920907.1 1623726 D 508767 CDS YP_001920908.1 188587847 6319547 1625609..1627009 1 NC_010723.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 1627009 6319547 CLH_1516 Clostridium botulinum E3 str. Alaska E43 aldehyde dehydrogenase YP_001920908.1 1625609 D 508767 CDS YP_001920909.1 188588062 6320437 1627365..1628693 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 1628693 6320437 CLH_1517 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001920909.1 1627365 D 508767 CDS YP_001920910.1 188588778 6318472 1628677..1630980 1 NC_010723.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1630980 gshAB 6318472 gshAB Clostridium botulinum E3 str. Alaska E43 bifunctional glutamate--cysteine ligase/glutathione synthetase YP_001920910.1 1628677 D 508767 CDS YP_001920911.1 188589927 6317638 1631248..1631757 1 NC_010723.1 identified by match to protein family HMM PF00293; nudix-family protein 1631757 6317638 CLH_1519 Clostridium botulinum E3 str. Alaska E43 nudix-family protein YP_001920911.1 1631248 D 508767 CDS YP_001920912.1 188590663 6319494 complement(1631847..1633202) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; putative integral membrane protein 1633202 6319494 CLH_1520 Clostridium botulinum E3 str. Alaska E43 putative integral membrane protein YP_001920912.1 1631847 R 508767 CDS YP_001920913.1 188589243 6318457 complement(1633404..1633715) 1 NC_010723.1 hypothetical protein 1633715 6318457 CLH_1521 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920913.1 1633404 R 508767 CDS YP_001920914.1 188590240 6317503 1634088..1634732 1 NC_010723.1 hypothetical protein 1634732 6317503 CLH_1522 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920914.1 1634088 D 508767 CDS YP_001920915.1 188588078 6318964 1635190..1635729 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1635729 6318964 CLH_1523 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920915.1 1635190 D 508767 CDS YP_001920916.1 188588841 6320604 1635716..1636114 1 NC_010723.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1636114 6320604 CLH_1524 Clostridium botulinum E3 str. Alaska E43 GntR family transcriptional regulator YP_001920916.1 1635716 D 508767 CDS YP_001920917.1 188590289 6318260 1636098..1636994 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1636994 6318260 CLH_1525 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001920917.1 1636098 D 508767 CDS YP_001920918.1 188588693 6318005 1636975..1638024 1 NC_010723.1 hypothetical protein 1638024 6318005 CLH_1526 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920918.1 1636975 D 508767 CDS YP_001920919.1 188587776 6320509 complement(1638222..1638377) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1638377 6320509 CLH_1527 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920919.1 1638222 R 508767 CDS YP_001920920.1 188590606 6319627 1638371..1638661 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1638661 6319627 CLH_1528 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920920.1 1638371 D 508767 CDS YP_001920921.1 188589639 6318497 1639018..1639728 1 NC_010723.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B 1639728 rluB 6318497 rluB Clostridium botulinum E3 str. Alaska E43 ribosomal large subunit pseudouridine synthase B YP_001920921.1 1639018 D 508767 CDS YP_001920922.1 188589149 6320092 1639903..1640808 1 NC_010723.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR-family transcriptional regulator 1640808 6320092 CLH_1530 Clostridium botulinum E3 str. Alaska E43 RpiR-family transcriptional regulator YP_001920922.1 1639903 D 508767 CDS YP_001920923.1 188588229 6319025 1640949..1642247 1 NC_010723.1 identified by match to protein family HMM PF01743; tRNA nucleotidyltransferase/poly(A) polymerase family protein 1642247 6319025 CLH_1531 Clostridium botulinum E3 str. Alaska E43 tRNA nucleotidyltransferase/poly(A) polymerase family protein YP_001920923.1 1640949 D 508767 CDS YP_001920924.1 188589421 6319629 1642266..1642544 1 NC_010723.1 hypothetical protein 1642544 6319629 CLH_1532 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920924.1 1642266 D 508767 CDS YP_001920925.1 188588493 6317748 1642841..1643803 1 NC_010723.1 alpha/beta hydrolase 1643803 6317748 CLH_1533 Clostridium botulinum E3 str. Alaska E43 alpha/beta hydrolase YP_001920925.1 1642841 D 508767 CDS YP_001920926.1 188587941 6319517 1644038..1644925 1 NC_010723.1 identified by match to protein family HMM PF04055; radical SAM domain protein 1644925 6319517 CLH_1534 Clostridium botulinum E3 str. Alaska E43 radical SAM domain protein YP_001920926.1 1644038 D 508767 CDS YP_001920927.1 188587962 6317571 1644998..1645228 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1645228 6317571 CLH_1535 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920927.1 1644998 D 508767 CDS YP_001920928.1 188590400 6317366 1645498..1646019 1 NC_010723.1 identified by match to protein family HMM PF04307; hypothetical protein 1646019 6317366 CLH_1536 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920928.1 1645498 D 508767 CDS YP_001920929.1 188588638 6320319 1646285..1646476 1 NC_010723.1 hypothetical protein 1646476 6320319 CLH_1537 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920929.1 1646285 D 508767 CDS YP_001920930.1 188587719 6320306 1646807..1648999 1 NC_010723.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1648999 topB 6320306 topB Clostridium botulinum E3 str. Alaska E43 DNA topoisomerase III YP_001920930.1 1646807 D 508767 CDS YP_001920931.1 188590103 6319061 1649414..1650481 1 NC_010723.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01714; N- phage replisome organizer 1650481 6319061 CLH_1539 Clostridium botulinum E3 str. Alaska E43 N- phage replisome organizer YP_001920931.1 1649414 D 508767 CDS YP_001920932.1 188589751 6317400 1650637..1651017 1 NC_010723.1 identified by match to protein family HMM PF00903; glyoxalase I 1651017 6317400 CLH_1540 Clostridium botulinum E3 str. Alaska E43 glyoxalase I YP_001920932.1 1650637 D 508767 CDS YP_001920933.1 188590697 6319893 1651260..1652333 1 NC_010723.1 identified by match to protein family HMM PF02698; integral membrane protein 1652333 6319893 CLH_1541 Clostridium botulinum E3 str. Alaska E43 integral membrane protein YP_001920933.1 1651260 D 508767 CDS YP_001920934.1 188588261 6318007 1652450..1652833 1 NC_010723.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1652833 mutT 6318007 mutT Clostridium botulinum E3 str. Alaska E43 MutT/nudix family protein YP_001920934.1 1652450 D 508767 CDS YP_001920935.1 188587615 6319862 1653194..1654576 1 NC_010723.1 identified by match to protein family HMM PF01547; sugar ABC transporter 1654576 6319862 CLH_1543 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter YP_001920935.1 1653194 D 508767 CDS YP_001920936.1 188589232 6319841 1654643..1655539 1 NC_010723.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease protein 1655539 6319841 CLH_1544 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter permease protein YP_001920936.1 1654643 D 508767 CDS YP_001920937.1 188587775 6317827 1655566..1656393 1 NC_010723.1 identified by match to protein family HMM PF00528; sugar ABC transporter 1656393 6317827 CLH_1545 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter YP_001920937.1 1655566 D 508767 CDS YP_001920938.1 188588128 6319626 1656407..1657495 1 NC_010723.1 identified by match to protein family HMM PF04041; hypothetical protein 1657495 6319626 CLH_1546 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920938.1 1656407 D 508767 CDS YP_001920939.1 188588684 6319148 1657564..1658625 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator 1658625 6319148 CLH_1547 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001920939.1 1657564 D 508767 CDS YP_001920940.1 188590484 6317771 1658639..1659556 1 NC_010723.1 hypothetical protein 1659556 6317771 CLH_1548 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920940.1 1658639 D 508767 CDS YP_001920941.1 188588122 6318880 1659571..1661172 1 NC_010723.1 identified by match to protein family HMM PF00128; trehalose-6-phosphate hydrolase 1661172 6318880 CLH_1549 Clostridium botulinum E3 str. Alaska E43 trehalose-6-phosphate hydrolase YP_001920941.1 1659571 D 508767 CDS YP_001920942.1 188587711 6319433 1661350..1662285 1 NC_010723.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 1662285 manA 6319433 manA Clostridium botulinum E3 str. Alaska E43 mannose-6-phosphate isomerase YP_001920942.1 1661350 D 508767 CDS YP_001920943.1 188590253 6319593 1662296..1662937 1 NC_010723.1 identified by match to protein family HMM PF00480; glucokinase 1662937 6319593 CLH_1551 Clostridium botulinum E3 str. Alaska E43 glucokinase YP_001920943.1 1662296 D 508767 CDS YP_001920944.1 188590411 6318067 1663042..1664253 1 NC_010723.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1664253 6318067 CLH_1552 Clostridium botulinum E3 str. Alaska E43 major facilitator family transporter YP_001920944.1 1663042 D 508767 CDS YP_001920945.1 188589791 6320272 1665133..1665897 1 NC_010723.1 identified by match to protein family HMM PF01473; match to protein family HMM PF09394; cell wall binding domain-containing protein 1665897 6320272 CLH_1555 Clostridium botulinum E3 str. Alaska E43 cell wall binding domain-containing protein YP_001920945.1 1665133 D 508767 CDS YP_001920946.1 188588127 6318629 1667280..1667687 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1667687 6318629 CLH_1558 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920946.1 1667280 D 508767 CDS YP_001920947.1 188589028 6319147 1667966..1668928 1 NC_010723.1 identified by match to protein family HMM PF08279; DeoR family transcriptional regulator 1668928 6319147 CLH_1559 Clostridium botulinum E3 str. Alaska E43 DeoR family transcriptional regulator YP_001920947.1 1667966 D 508767 CDS YP_001920948.1 188589420 6318355 1669029..1669655 1 NC_010723.1 identified by match to protein family HMM PF01965; intracellular protease, ThiJ/PfpI family 1669655 6318355 CLH_1560 Clostridium botulinum E3 str. Alaska E43 intracellular protease, ThiJ/PfpI family YP_001920948.1 1669029 D 508767 CDS YP_001920949.1 188590389 6320390 1669796..1670446 1 NC_010723.1 hypothetical protein 1670446 6320390 CLH_1561 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920949.1 1669796 D 508767 CDS YP_001920950.1 188587605 6320467 1671139..1671591 1 NC_010723.1 identified by match to protein family HMM PF04266; match to protein family HMM PF06171; hypothetical protein 1671591 6320467 CLH_1562 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920950.1 1671139 D 508767 CDS YP_001920951.1 188588521 6319854 complement(1671938..1673173) 1 NC_010723.1 identified by match to protein family HMM PF01071; match to protein family HMM PF02655; hypothetical protein 1673173 6319854 CLH_1563 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920951.1 1671938 R 508767 CDS YP_001920952.1 188589839 6320542 complement(1673163..1674383) 1 NC_010723.1 identified by match to protein family HMM PF07690; transporter 1674383 6320542 CLH_1564 Clostridium botulinum E3 str. Alaska E43 transporter YP_001920952.1 1673163 R 508767 CDS YP_001920953.1 188590702 6317584 complement(1674509..1675543) 1 NC_010723.1 identified by match to protein family HMM PF00587; match to protein family HMM PF03129; threonyl-tRNA synthetase 1 1675543 6317584 CLH_1565 Clostridium botulinum E3 str. Alaska E43 threonyl-tRNA synthetase 1 YP_001920953.1 1674509 R 508767 CDS YP_001920954.1 188588717 6320202 1676265..1676447 1 NC_010723.1 hypothetical protein 1676447 6320202 CLH_1566 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920954.1 1676265 D 508767 CDS YP_001920955.1 188588777 6317806 1676668..1677942 1 NC_010723.1 identified by match to protein family HMM PF03572; peptidase, S41 family 1677942 6317806 CLH_1567 Clostridium botulinum E3 str. Alaska E43 peptidase, S41 family YP_001920955.1 1676668 D 508767 CDS YP_001920956.1 188590729 6317382 1677993..1679249 1 NC_010723.1 putative cytoplasmic protein 1679249 6317382 CLH_1568 Clostridium botulinum E3 str. Alaska E43 putative cytoplasmic protein YP_001920956.1 1677993 D 508767 CDS YP_001920957.1 188589951 6318825 1679349..1680536 1 NC_010723.1 identified by match to protein family HMM PF00165; match to protein family HMM PF09370; AraC family transcriptional regulator 1680536 6318825 CLH_1569 Clostridium botulinum E3 str. Alaska E43 AraC family transcriptional regulator YP_001920957.1 1679349 D 508767 CDS YP_001920958.1 188589891 6319697 1680681..1681889 1 NC_010723.1 identified by match to protein family HMM PF06792; hypothetical protein 1681889 6319697 CLH_1570 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920958.1 1680681 D 508767 CDS YP_001920959.1 188589147 6318752 1681994..1682815 1 NC_010723.1 identified by match to protein family HMM PF09370; transcriptional regulator 1682815 6318752 CLH_1571 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001920959.1 1681994 D 508767 CDS YP_001920960.1 188588403 6319871 1683276..1683704 1 NC_010723.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220; large conductance mechanosensitive channel protein 1683704 mscL 6319871 mscL Clostridium botulinum E3 str. Alaska E43 large conductance mechanosensitive channel protein YP_001920960.1 1683276 D 508767 CDS YP_001920961.1 188587742 6320607 1684249..1684920 1 NC_010723.1 identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073; hydrogenase nickel incorporation protein HypB 1684920 hypB 6320607 hypB Clostridium botulinum E3 str. Alaska E43 hydrogenase nickel incorporation protein HypB YP_001920961.1 1684249 D 508767 CDS YP_001920962.1 188589483 6319851 1684952..1687642 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00070; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 1687642 6319851 CLH_1574 Clostridium botulinum E3 str. Alaska E43 pyridine nucleotide-disulfide oxidoreductase family protein YP_001920962.1 1684952 D 508767 CDS YP_001920963.1 188588386 6319228 1687751..1688092 1 NC_010723.1 identified by match to protein family HMM PF01155; hydrogenase nickel incorporation protein 1688092 6319228 CLH_1575 Clostridium botulinum E3 str. Alaska E43 hydrogenase nickel incorporation protein YP_001920963.1 1687751 D 508767 CDS YP_001920964.1 188588136 6319975 1688343..1689404 1 NC_010723.1 identified by match to protein family HMM PF01891; cobalamin 1689404 6319975 CLH_1576 Clostridium botulinum E3 str. Alaska E43 cobalamin YP_001920964.1 1688343 D 508767 CDS YP_001920965.1 188590219 6318299 1689426..1690232 1 NC_010723.1 identified by match to protein family HMM PF02361; match to protein family HMM TIGR02454; cobalt ABC transporter permease CbiQ 1690232 cbiQ 6318299 cbiQ Clostridium botulinum E3 str. Alaska E43 cobalt ABC transporter permease CbiQ YP_001920965.1 1689426 D 508767 CDS YP_001920966.1 188589049 6320451 1690233..1690949 1 NC_010723.1 identified by match to protein family HMM PF00005; cobalt import ATP-binding protein CbiO 1690949 6320451 CLH_1578 Clostridium botulinum E3 str. Alaska E43 cobalt import ATP-binding protein CbiO YP_001920966.1 1690233 D 508767 CDS YP_001920967.1 188588694 6319942 complement(1691142..1692065) 1 NC_010723.1 hypothetical protein 1692065 6319942 CLH_1579 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920967.1 1691142 R 508767 CDS YP_001920968.1 188590574 6320510 complement(1692647..1693114) 1 NC_010723.1 identified by match to protein family HMM PF01272; match to protein family HMM PF03449; match to protein family HMM TIGR01462; transcription elongation factor GreA 1693114 6320510 CLH_1580 Clostridium botulinum E3 str. Alaska E43 transcription elongation factor GreA YP_001920968.1 1692647 R 508767 CDS YP_001920969.1 188589678 6318802 1693255..1695072 1 NC_010723.1 identified by match to protein family HMM PF00082; CspA protein 1695072 6318802 CLH_1581 Clostridium botulinum E3 str. Alaska E43 CspA protein YP_001920969.1 1693255 D 508767 CDS YP_001920970.1 188589077 6318056 1695092..1696819 1 NC_010723.1 identified by match to protein family HMM PF00082; protein CspC 1696819 6318056 CLH_1582 Clostridium botulinum E3 str. Alaska E43 protein CspC YP_001920970.1 1695092 D 508767 CDS YP_001920971.1 188588313 6318513 1697013..1697942 1 NC_010723.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1697942 6318513 CLH_1583 Clostridium botulinum E3 str. Alaska E43 DNA polymerase III subunit epsilon YP_001920971.1 1697013 D 508767 CDS YP_001920972.1 188590573 6319987 complement(1698172..1699365) 1 NC_010723.1 hypothetical protein 1699365 6319987 CLH_1584 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920972.1 1698172 R 508767 CDS YP_001920973.1 188589642 6318801 1699481..1700362 1 NC_010723.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR-family transcriptional regulator 1700362 6318801 CLH_1585 Clostridium botulinum E3 str. Alaska E43 LysR-family transcriptional regulator YP_001920973.1 1699481 D 508767 CDS YP_001920974.1 188589093 6320457 complement(1700565..1701296) 1 NC_010723.1 identified by match to protein family HMM PF00929; exonuclease 1701296 6320457 CLH_1586 Clostridium botulinum E3 str. Alaska E43 exonuclease YP_001920974.1 1700565 R 508767 CDS YP_001920975.1 188588205 6318169 1701996..1702931 1 NC_010723.1 hypothetical protein 1702931 6318169 CLH_1587 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920975.1 1701996 D 508767 CDS YP_001920976.1 188590136 6319712 1703060..1703206 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1703206 6319712 CLH_1588 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920976.1 1703060 D 508767 CDS YP_001920977.1 188589101 6317738 1703490..1704080 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1704080 6317738 CLH_1589 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920977.1 1703490 D 508767 CDS YP_001920978.1 188588164 6318232 1704613..1706268 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1706268 6318232 CLH_1590 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001920978.1 1704613 D 508767 CDS YP_001920979.1 188590290 6319502 1706539..1707729 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1707729 6319502 CLH_1591 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920979.1 1706539 D 508767 CDS YP_001920980.1 188588361 6318992 1707969..1717211 1 NC_010723.1 identified by match to protein family HMM PF06165; match to protein family HMM PF06204; match to protein family HMM PF06205; hypothetical protein 1717211 6318992 CLH_1592 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920980.1 1707969 D 508767 CDS YP_001920981.1 188587655 6319623 complement(1717454..1718275) 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00881; nitroreductase family protein fused to ferredoxin domain 1718275 6319623 CLH_1593 Clostridium botulinum E3 str. Alaska E43 nitroreductase family protein fused to ferredoxin domain YP_001920981.1 1717454 R 508767 CDS YP_001920982.1 188588621 6319611 1718724..1719605 1 NC_010723.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator, LysR family 1719605 6319611 CLH_1594 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, LysR family YP_001920982.1 1718724 D 508767 CDS YP_001920983.1 188587809 6317718 1720112..1721053 1 NC_010723.1 identified by match to protein family HMM PF01058; match to protein family HMM TIGR00391; [Ni/Fe] hydrogenase, small subunit 1721053 hupS 6317718 hupS Clostridium botulinum E3 str. Alaska E43 [Ni/Fe] hydrogenase, small subunit YP_001920983.1 1720112 D 508767 CDS YP_001920984.1 188590480 6319510 1721058..1722473 1 NC_010723.1 identified by match to protein family HMM PF00374; [Ni/Fe] hydrogenase, large subunit 1722473 hupL 6319510 hupL Clostridium botulinum E3 str. Alaska E43 [Ni/Fe] hydrogenase, large subunit YP_001920984.1 1721058 D 508767 CDS YP_001920985.1 188589756 6318968 1722470..1722943 1 NC_010723.1 identified by match to protein family HMM TIGR00072; hydrogenase maturation protease superfamily 1722943 6318968 CLH_1597 Clostridium botulinum E3 str. Alaska E43 hydrogenase maturation protease superfamily YP_001920985.1 1722470 D 508767 CDS YP_001920986.1 188589001 6319390 1723059..1723400 1 NC_010723.1 identified by match to protein family HMM PF01155; putative hydrogenase nickel incorporation protein 1723400 6319390 CLH_1598 Clostridium botulinum E3 str. Alaska E43 putative hydrogenase nickel incorporation protein YP_001920986.1 1723059 D 508767 CDS YP_001920987.1 188590247 6319866 1723415..1725766 1 NC_010723.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143; [NiFe] hydrogenase maturation protein HypF 1725766 hypF 6319866 hypF Clostridium botulinum E3 str. Alaska E43 [NiFe] hydrogenase maturation protein HypF YP_001920987.1 1723415 D 508767 CDS YP_001920988.1 188590454 6317383 1725784..1725999 1 NC_010723.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074; hydrogenase assembly chaperone HypC/HupF 1725999 hypC 6317383 hypC Clostridium botulinum E3 str. Alaska E43 hydrogenase assembly chaperone HypC/HupF YP_001920988.1 1725784 D 508767 CDS YP_001920989.1 188588659 6317365 1726164..1727177 1 NC_010723.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124; hydrogenase expression/formation protein HypE 1727177 hypE 6317365 hypE Clostridium botulinum E3 str. Alaska E43 hydrogenase expression/formation protein HypE YP_001920989.1 1726164 D 508767 CDS YP_001920990.1 188587641 6318076 1727316..1728323 1 NC_010723.1 identified by match to protein family HMM PF01924; hydrogenase expression/formation protein HypD 1728323 6318076 CLH_1602 Clostridium botulinum E3 str. Alaska E43 hydrogenase expression/formation protein HypD YP_001920990.1 1727316 D 508767 CDS YP_001920991.1 188590023 6319427 1728525..1728656 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1728656 6319427 CLH_1603 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920991.1 1728525 D 508767 CDS YP_001920992.1 188589939 6319999 1728944..1730884 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512; periplasmic [Fe] hydrogenase 1 1730884 6319999 CLH_1604 Clostridium botulinum E3 str. Alaska E43 periplasmic [Fe] hydrogenase 1 YP_001920992.1 1728944 D 508767 CDS YP_001920993.1 188588910 6317295 1733111..1734793 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis sensory transducer 1734793 6317295 CLH_1607 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis sensory transducer YP_001920993.1 1733111 D 508767 CDS YP_001920994.1 188587987 6320358 1735647..1736147 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1736147 6320358 CLH_1608 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920994.1 1735647 D 508767 CDS YP_001920995.1 188588603 6318425 1736429..1737751 1 NC_010723.1 identified by match to protein family HMM PF00860; xanthine/uracil permease family protein 1737751 6318425 CLH_1609 Clostridium botulinum E3 str. Alaska E43 xanthine/uracil permease family protein YP_001920995.1 1736429 D 508767 CDS YP_001920996.1 188589263 6317598 1738021..1740084 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 1740084 6317598 CLH_1610 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001920996.1 1738021 D 508767 CDS YP_001920997.1 188588070 6318571 1740507..1740728 1 NC_010723.1 hypothetical protein 1740728 6318571 CLH_1611 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001920997.1 1740507 D 508767 CDS YP_001920998.1 188588970 6319016 1740935..1741711 1 NC_010723.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family protein 1741711 6319016 CLH_1612 Clostridium botulinum E3 str. Alaska E43 endonuclease/exonuclease/phosphatase family protein YP_001920998.1 1740935 D 508767 CDS YP_001920999.1 188589460 6319659 1741986..1742918 1 NC_010723.1 identified by match to protein family HMM PF00005; bacitracin transport ATP-binding protein BcrA 1742918 6319659 CLH_1613 Clostridium botulinum E3 str. Alaska E43 bacitracin transport ATP-binding protein BcrA YP_001920999.1 1741986 D 508767 CDS YP_001921000.1 188590405 6317321 1742933..1744618 1 NC_010723.1 putative permease 1744618 6317321 CLH_1614 Clostridium botulinum E3 str. Alaska E43 putative permease YP_001921000.1 1742933 D 508767 CDS YP_001921001.1 188589429 6317606 1744801..1745478 1 NC_010723.1 identified by match to protein family HMM PF00005; lipoprotein-releasing system ATP-binding protein LolD 1745478 6317606 CLH_1615 Clostridium botulinum E3 str. Alaska E43 lipoprotein-releasing system ATP-binding protein LolD YP_001921001.1 1744801 D 508767 CDS YP_001921002.1 188590360 6318082 1745481..1748084 1 NC_010723.1 identified by match to protein family HMM PF02687; putative ABC transporter-associated permease 1748084 6318082 CLH_1616 Clostridium botulinum E3 str. Alaska E43 putative ABC transporter-associated permease YP_001921002.1 1745481 D 508767 CDS YP_001921003.1 188587543 6317500 1748113..1748811 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two component response regulator 1748811 6317500 CLH_1617 Clostridium botulinum E3 str. Alaska E43 two component response regulator YP_001921003.1 1748113 D 508767 CDS YP_001921004.1 188588438 6319127 1748811..1750061 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; two component sensor kinase 1750061 6319127 CLH_1618 Clostridium botulinum E3 str. Alaska E43 two component sensor kinase YP_001921004.1 1748811 D 508767 CDS YP_001921005.1 188588163 6319793 complement(1750180..1751052) 1 NC_010723.1 identified by match to protein family HMM PF00892; putative integral membrane protein 1751052 6319793 CLH_1619 Clostridium botulinum E3 str. Alaska E43 putative integral membrane protein YP_001921005.1 1750180 R 508767 CDS YP_001921006.1 188588473 6319501 1751262..1751912 1 NC_010723.1 hypothetical protein 1751912 6319501 CLH_1620 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921006.1 1751262 D 508767 CDS YP_001921007.1 188589574 6319217 complement(1752201..1752575) 1 NC_010723.1 identified by match to protein family HMM PF08000; hypothetical protein 1752575 6319217 CLH_1621 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921007.1 1752201 R 508767 CDS YP_001921008.1 188590246 6319779 1752927..1753565 1 NC_010723.1 hypothetical protein 1753565 6319779 CLH_1622 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921008.1 1752927 D 508767 CDS YP_001921009.1 188588642 6317653 complement(1754629..1755528) 1 NC_010723.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator, LysR family 1755528 6317653 CLH_1623 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, LysR family YP_001921009.1 1754629 R 508767 CDS YP_001921010.1 188588912 6317769 1755702..1756940 1 NC_010723.1 identified by match to protein family HMM PF07690; major facilitator superfamily protein 1756940 6317769 CLH_1624 Clostridium botulinum E3 str. Alaska E43 major facilitator superfamily protein YP_001921010.1 1755702 D 508767 CDS YP_001921011.1 188589665 6320360 1757165..1758373 1 NC_010723.1 acetyltransferase 1758373 6320360 CLH_1625 Clostridium botulinum E3 str. Alaska E43 acetyltransferase YP_001921011.1 1757165 D 508767 CDS YP_001921012.1 188590728 6320611 1758700..1759890 1 NC_010723.1 putative rhoptry protein 1759890 6320611 CLH_1626 Clostridium botulinum E3 str. Alaska E43 putative rhoptry protein YP_001921012.1 1758700 D 508767 CDS YP_001921013.1 188590436 6318824 1760104..1760568 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1760568 6318824 CLH_1627 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921013.1 1760104 D 508767 CDS YP_001921014.1 188588348 6320424 1760731..1761690 1 NC_010723.1 hypothetical protein 1761690 6320424 CLH_1628 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921014.1 1760731 D 508767 CDS YP_001921015.1 188588232 6318166 complement(1761791..1762285) 1 NC_010723.1 hypothetical protein 1762285 6318166 CLH_1629 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921015.1 1761791 R 508767 CDS YP_001921016.1 188590031 6319614 1762423..1763157 1 NC_010723.1 identified by match to protein family HMM PF00515; putative TPR repeat-containing protein 1763157 6319614 CLH_1630 Clostridium botulinum E3 str. Alaska E43 putative TPR repeat-containing protein YP_001921016.1 1762423 D 508767 CDS YP_001921017.1 188588207 6317908 1763328..1764986 1 NC_010723.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1764986 hcp 6317908 hcp Clostridium botulinum E3 str. Alaska E43 hydroxylamine reductase YP_001921017.1 1763328 D 508767 CDS YP_001921018.1 188588580 6319714 1765280..1765933 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD-superfamily hydrolase 1765933 6319714 CLH_1632 Clostridium botulinum E3 str. Alaska E43 HAD-superfamily hydrolase YP_001921018.1 1765280 D 508767 CDS YP_001921019.1 188589227 6318303 1766356..1768263 1 NC_010723.1 identified by match to protein family HMM PF00488; DNA mismatch repair protein 1768263 6318303 CLH_1633 Clostridium botulinum E3 str. Alaska E43 DNA mismatch repair protein YP_001921019.1 1766356 D 508767 CDS YP_001921020.1 188588038 6320371 1768470..1768898 1 NC_010723.1 identified by match to protein family HMM PF01047; putative transcriptional regulator 1768898 6320371 CLH_1634 Clostridium botulinum E3 str. Alaska E43 putative transcriptional regulator YP_001921020.1 1768470 D 508767 CDS YP_001921021.1 188588902 6319221 1768948..1769973 1 NC_010723.1 hypothetical protein 1769973 6319221 CLH_1635 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921021.1 1768948 D 508767 CDS YP_001921022.1 188589804 6318551 1770863..1771978 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensory box histidine kinase 1771978 6318551 CLH_1636 Clostridium botulinum E3 str. Alaska E43 sensory box histidine kinase YP_001921022.1 1770863 D 508767 CDS YP_001921023.1 188590764 6319430 1772575..1774134 1 NC_010723.1 putative xanthine/uracil/vitamin C permease 1774134 6319430 CLH_1637 Clostridium botulinum E3 str. Alaska E43 putative xanthine/uracil/vitamin C permease YP_001921023.1 1772575 D 508767 CDS YP_001921024.1 188589821 6318518 1774131..1775093 1 NC_010723.1 catalyzes the reversible formation of methenyl-H(4)methanopterin from N(5)-formyl-H(4)methanopterin; N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase 1775093 mch 6318518 mch Clostridium botulinum E3 str. Alaska E43 N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase YP_001921024.1 1774131 D 508767 CDS YP_001921025.1 188589545 6319834 1775156..1775887 1 NC_010723.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase 1775887 6319834 CLH_1639 Clostridium botulinum E3 str. Alaska E43 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase YP_001921025.1 1775156 D 508767 CDS YP_001921026.1 188590252 6317937 1775914..1776870 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1776870 6317937 CLH_1640 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921026.1 1775914 D 508767 CDS YP_001921027.1 188587731 6317744 1776951..1778513 1 NC_010723.1 putative permease 1778513 6317744 CLH_1641 Clostridium botulinum E3 str. Alaska E43 putative permease YP_001921027.1 1776951 D 508767 CDS YP_001921028.1 188590372 6318670 complement(1778555..1779694) 1 NC_010723.1 identified by match to protein family HMM PF00480; putative transcriptional repressor of the xylose operon 1779694 6318670 CLH_1642 Clostridium botulinum E3 str. Alaska E43 putative transcriptional repressor of the xylose operon YP_001921028.1 1778555 R 508767 CDS YP_001921029.1 188587625 6320505 1780041..1780598 1 NC_010723.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; iron-sulfur flavoprotein 1780598 6320505 CLH_1643 Clostridium botulinum E3 str. Alaska E43 iron-sulfur flavoprotein YP_001921029.1 1780041 D 508767 CDS YP_001921030.1 188588530 6319651 complement(1780660..1782408) 1 NC_010723.1 identified by similarity to SP:P29166; match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512; iron hydrogenase 1 1782408 6319651 CLH_1644 Clostridium botulinum E3 str. Alaska E43 iron hydrogenase 1 YP_001921030.1 1780660 R 508767 CDS YP_001921031.1 188590725 6318401 complement(1782402..1784237) 1 NC_010723.1 unknown function; putative glutamate synthase (NADPH) small subunit 1784237 6318401 CLH_1645 Clostridium botulinum E3 str. Alaska E43 putative glutamate synthase (NADPH) small subunit YP_001921031.1 1782402 R 508767 CDS YP_001921032.1 188588324 6318798 1784556..1784873 1 NC_010723.1 MazG nucleotide pyrophosphohydrolase domain-containing protein 1784873 6318798 CLH_1646 Clostridium botulinum E3 str. Alaska E43 MazG nucleotide pyrophosphohydrolase domain-containing protein YP_001921032.1 1784556 D 508767 CDS YP_001921033.1 188588871 6319945 1785046..1786458 1 NC_010723.1 identified by match to protein family HMM PF00324; amino acid permease family protein 1786458 6319945 CLH_1647 Clostridium botulinum E3 str. Alaska E43 amino acid permease family protein YP_001921033.1 1785046 D 508767 CDS YP_001921034.1 188589412 6319019 complement(1786521..1786883) 1 NC_010723.1 identified by match to protein family HMM PF09719; match to protein family HMM TIGR01909; hypothetical protein 1786883 6319019 CLH_1648 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921034.1 1786521 R 508767 CDS YP_001921035.1 188590708 6320447 1787256..1789250 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM TIGR00229; sensory transduction histidine kinase 1789250 6320447 CLH_1649 Clostridium botulinum E3 str. Alaska E43 sensory transduction histidine kinase YP_001921035.1 1787256 D 508767 CDS YP_001921036.1 188588135 6318736 1789330..1790877 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM TIGR00229; sensory transduction histidine kinase 1790877 6318736 CLH_1650 Clostridium botulinum E3 str. Alaska E43 sensory transduction histidine kinase YP_001921036.1 1789330 D 508767 CDS YP_001921037.1 188590643 6318298 1790912..1792672 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM TIGR00229; two-component sensor histidine kinase 1792672 6318298 CLH_1651 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001921037.1 1790912 D 508767 CDS YP_001921038.1 188589896 6319293 1792844..1793800 1 NC_010723.1 hypothetical protein 1793800 6319293 CLH_1652 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921038.1 1792844 D 508767 CDS YP_001921039.1 188588356 6318862 complement(1793861..1794439) 1 NC_010723.1 hypothetical protein 1794439 6318862 CLH_1653 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921039.1 1793861 R 508767 CDS YP_001921040.1 188587674 6319899 1794671..1795480 1 NC_010723.1 identified by match to protein family HMM PF08238; Sel1 repeat family 1795480 6319899 CLH_1654 Clostridium botulinum E3 str. Alaska E43 Sel1 repeat family YP_001921040.1 1794671 D 508767 CDS YP_001921041.1 188590384 6318126 1795862..1797418 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; membrane-associated methyl-accepting chemotaxis protein with hamp domain 1797418 6318126 CLH_1655 Clostridium botulinum E3 str. Alaska E43 membrane-associated methyl-accepting chemotaxis protein with hamp domain YP_001921041.1 1795862 D 508767 CDS YP_001921042.1 188590434 6318645 1797805..1799607 1 NC_010723.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR02290; oligoendopeptidase F 1799607 6318645 CLH_1656 Clostridium botulinum E3 str. Alaska E43 oligoendopeptidase F YP_001921042.1 1797805 D 508767 CDS YP_001921043.1 188590438 6320422 1799771..1801144 1 NC_010723.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933; V-type sodium ATP synthase subunit J 1801144 6320422 CLH_1657 Clostridium botulinum E3 str. Alaska E43 V-type sodium ATP synthase subunit J YP_001921043.1 1799771 D 508767 CDS YP_001921044.1 188590256 6318198 1801350..1802186 1 NC_010723.1 identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family 1802186 6318198 CLH_1658 Clostridium botulinum E3 str. Alaska E43 oxidoreductase, aldo/keto reductase family YP_001921044.1 1801350 D 508767 CDS YP_001921045.1 188589803 6320066 1802480..1803691 1 NC_010723.1 identified by match to protein family HMM PF06580; two-component sensor histidine kinase 1803691 6320066 CLH_1659 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001921045.1 1802480 D 508767 CDS YP_001921046.1 188588458 6319429 1803885..1804601 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; transcriptional regulatory protein 1804601 6319429 CLH_1660 Clostridium botulinum E3 str. Alaska E43 transcriptional regulatory protein YP_001921046.1 1803885 D 508767 CDS YP_001921047.1 188588000 6319821 1804845..1807256 1 NC_010723.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774; pyruvate formate-lyase 1807256 6319821 CLH_1661 Clostridium botulinum E3 str. Alaska E43 pyruvate formate-lyase YP_001921047.1 1804845 D 508767 CDS YP_001921048.1 188590775 6320209 1807320..1808252 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating family protein 1808252 6320209 CLH_1662 Clostridium botulinum E3 str. Alaska E43 glycyl-radical enzyme activating family protein YP_001921048.1 1807320 D 508767 CDS YP_001921049.1 188588669 6317950 1808380..1808517 1 NC_010723.1 hypothetical protein 1808517 6317950 CLH_1663 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921049.1 1808380 D 508767 CDS YP_001921050.1 188588939 6318073 1808837..1810465 1 NC_010723.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872; 2',3'-cyclic-nucleotide 2'-phosphodiesterase 1810465 6318073 CLH_1664 Clostridium botulinum E3 str. Alaska E43 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_001921050.1 1808837 D 508767 CDS YP_001921051.1 188590263 6318906 complement(1810570..1810695) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1810695 6318906 CLH_1665 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921051.1 1810570 R 508767 CDS YP_001921052.1 188589207 6317858 1811113..1811673 1 NC_010723.1 identified by match to protein family HMM PF00293; nudix domain protein 1811673 6317858 CLH_1666 Clostridium botulinum E3 str. Alaska E43 nudix domain protein YP_001921052.1 1811113 D 508767 CDS YP_001921053.1 188588783 6317632 complement(1811726..1812178) 1 NC_010723.1 identified by match to protein family HMM PF00293; putative MutT/nudix family protein 1812178 6317632 CLH_1667 Clostridium botulinum E3 str. Alaska E43 putative MutT/nudix family protein YP_001921053.1 1811726 R 508767 CDS YP_001921054.1 188588202 6318300 1812416..1813030 1 NC_010723.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; Mn/Fe superoxide dismutase 1813030 6318300 CLH_1668 Clostridium botulinum E3 str. Alaska E43 Mn/Fe superoxide dismutase YP_001921054.1 1812416 D 508767 CDS YP_001921055.1 188590012 6319513 complement(1813187..1814293) 1 NC_010723.1 hypothetical protein 1814293 6319513 CLH_1669 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921055.1 1813187 R 508767 CDS YP_001921056.1 188589118 6320380 complement(1814322..1815227) 1 NC_010723.1 hypothetical protein 1815227 6320380 CLH_1670 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921056.1 1814322 R 508767 CDS YP_001921057.1 188588566 6318351 complement(1815534..1817027) 1 NC_010723.1 identified by match to protein family HMM PF01593; match to protein family HMM TIGR02734; phytoene dehydrogenase family protein 1817027 6318351 CLH_1671 Clostridium botulinum E3 str. Alaska E43 phytoene dehydrogenase family protein YP_001921057.1 1815534 R 508767 CDS YP_001921058.1 188587667 6318413 1817356..1817766 1 NC_010723.1 hypothetical protein 1817766 6318413 CLH_1672 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921058.1 1817356 D 508767 CDS YP_001921059.1 188589915 6319396 1818024..1819955 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein uup 1819955 6319396 CLH_1673 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein uup YP_001921059.1 1818024 D 508767 CDS YP_001921060.1 188588984 6317516 1819969..1820157 1 NC_010723.1 hypothetical protein 1820157 6317516 CLH_1674 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921060.1 1819969 D 508767 CDS YP_001921061.1 188587846 6320393 1820178..1823438 1 NC_010723.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455; SWI/SNF family helicase 1823438 6320393 CLH_1675 Clostridium botulinum E3 str. Alaska E43 SWI/SNF family helicase YP_001921061.1 1820178 D 508767 CDS YP_001921062.1 188590616 6317625 1823710..1824408 1 NC_010723.1 identified by match to protein family HMM PF02308; MgtC/SapB transporter 1824408 6317625 CLH_1676 Clostridium botulinum E3 str. Alaska E43 MgtC/SapB transporter YP_001921062.1 1823710 D 508767 CDS YP_001921063.1 188589194 6320238 1824546..1825274 1 NC_010723.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 1825274 6320238 CLH_1677 Clostridium botulinum E3 str. Alaska E43 glycerophosphoryl diester phosphodiesterase family protein YP_001921063.1 1824546 D 508767 CDS YP_001921064.1 188588478 6319046 1825420..1826118 1 NC_010723.1 identified by match to protein family HMM PF02308; MgtC/SapB transporter 1826118 6319046 CLH_1678 Clostridium botulinum E3 str. Alaska E43 MgtC/SapB transporter YP_001921064.1 1825420 D 508767 CDS YP_001921065.1 188588983 6319278 1826497..1827300 1 NC_010723.1 hypothetical protein 1827300 6319278 CLH_1679 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921065.1 1826497 D 508767 CDS YP_001921066.1 188589938 6320392 1827300..1828127 1 NC_010723.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1828127 panB 6320392 panB Clostridium botulinum E3 str. Alaska E43 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001921066.1 1827300 D 508767 CDS YP_001921067.1 188588201 6319990 1828146..1828988 1 NC_010723.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 1828988 panC 6319990 panC Clostridium botulinum E3 str. Alaska E43 pantoate--beta-alanine ligase YP_001921067.1 1828146 D 508767 CDS YP_001921068.1 188589121 6319522 1829134..1829508 1 NC_010723.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 1829508 panD 6319522 panD Clostridium botulinum E3 str. Alaska E43 aspartate alpha-decarboxylase YP_001921068.1 1829134 D 508767 CDS YP_001921069.1 188589274 6319740 1829909..1830931 1 NC_010723.1 identified by match to protein family HMM PF04055; spore photoproduct lyase 1830931 6319740 CLH_1683 Clostridium botulinum E3 str. Alaska E43 spore photoproduct lyase YP_001921069.1 1829909 D 508767 CDS YP_001921070.1 188590144 6317819 1831262..1834087 1 NC_010723.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1834087 mutS 6317819 mutS Clostridium botulinum E3 str. Alaska E43 DNA mismatch repair protein MutS YP_001921070.1 1831262 D 508767 CDS YP_001921071.1 188588754 6318428 1834112..1834279 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1834279 6318428 CLH_1685 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921071.1 1834112 D 508767 CDS YP_001921072.1 188589236 6317781 1834573..1835979 1 NC_010723.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01992; PTS system trehalose-specific transporter subunit IIBC 1835979 treP 6317781 treP Clostridium botulinum E3 str. Alaska E43 PTS system trehalose-specific transporter subunit IIBC YP_001921072.1 1834573 D 508767 CDS YP_001921073.1 188589618 6317791 1836014..1837672 1 NC_010723.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; alpha,alpha-phosphotrehalase 1837672 treC 6317791 treC Clostridium botulinum E3 str. Alaska E43 alpha,alpha-phosphotrehalase YP_001921073.1 1836014 D 508767 CDS YP_001921074.1 188590090 6319140 1837709..1838422 1 NC_010723.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404; trehalose operon repressor 1838422 treR 6319140 treR Clostridium botulinum E3 str. Alaska E43 trehalose operon repressor YP_001921074.1 1837709 D 508767 CDS YP_001921075.1 188588377 6317617 1838662..1840692 1 NC_010723.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1840692 mutL 6317617 mutL Clostridium botulinum E3 str. Alaska E43 DNA mismatch repair protein YP_001921075.1 1838662 D 508767 CDS YP_001921076.1 188588295 6318237 1840696..1841625 1 NC_010723.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1841625 miaA 6318237 miaA Clostridium botulinum E3 str. Alaska E43 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001921076.1 1840696 D 508767 CDS YP_001921077.1 188590515 6319746 1841675..1841908 1 NC_010723.1 identified by match to protein family HMM PF01423; match to protein family HMM TIGR02383; RNA chaperone Hfq 1841908 hfq 6319746 hfq Clostridium botulinum E3 str. Alaska E43 RNA chaperone Hfq YP_001921077.1 1841675 D 508767 CDS YP_001921078.1 188589793 6318042 1841984..1843273 1 NC_010723.1 identified by match to protein family HMM PF06838; aluminium resistance protein 1843273 6318042 CLH_1692 Clostridium botulinum E3 str. Alaska E43 aluminium resistance protein YP_001921078.1 1841984 D 508767 CDS YP_001921079.1 188588091 6319480 complement(1843445..1844050) 1 NC_010723.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 1844050 lexA 6319480 lexA Clostridium botulinum E3 str. Alaska E43 LexA repressor YP_001921079.1 1843445 R 508767 CDS YP_001921080.1 188587813 6319879 1844226..1844657 1 NC_010723.1 hypothetical protein 1844657 6319879 CLH_1694 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921080.1 1844226 D 508767 CDS YP_001921081.1 188590362 6319993 1844727..1845218 1 NC_010723.1 putative lipoprotein 1845218 6319993 CLH_1695 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921081.1 1844727 D 508767 CDS YP_001921082.1 188589315 6317502 1845401..1845931 1 NC_010723.1 putative lipoprotein 1845931 6317502 CLH_1696 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921082.1 1845401 D 508767 CDS YP_001921083.1 188587679 6317636 complement(1846045..1847034) 1 NC_010723.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1847034 xerC 6317636 xerC Clostridium botulinum E3 str. Alaska E43 site-specific tyrosine recombinase XerC YP_001921083.1 1846045 R 508767 CDS YP_001921084.1 188589026 6318623 1847705..1848184 1 NC_010723.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011; hypothetical protein 1848184 ybaK 6318623 ybaK Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921084.1 1847705 D 508767 CDS YP_001921085.1 188589964 6317630 complement(1848507..1849877) 1 NC_010723.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1849877 miaB 6317630 miaB Clostridium botulinum E3 str. Alaska E43 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001921085.1 1848507 R 508767 CDS YP_001921086.1 188588254 6318318 complement(1850114..1850326) 1 NC_010723.1 identified by match to protein family HMM PF01381; putative transcriptional regulator 1850326 6318318 CLH_1700 Clostridium botulinum E3 str. Alaska E43 putative transcriptional regulator YP_001921086.1 1850114 R 508767 CDS YP_001921087.1 188588773 6319884 complement(1850836..1851624) 1 NC_010723.1 identified by match to protein family HMM PF00959; match to protein family HMM PF01473; putative phage lysozyme 1851624 6319884 CLH_1701 Clostridium botulinum E3 str. Alaska E43 putative phage lysozyme YP_001921087.1 1850836 R 508767 CDS YP_001921088.1 188589687 6318450 complement(1851682..1851855) 1 NC_010723.1 hypothetical protein 1851855 6318450 CLH_1702 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921088.1 1851682 R 508767 CDS YP_001921089.1 188589390 6319954 complement(1851868..1852068) 1 NC_010723.1 UviB-like protein 1852068 6319954 CLH_1703 Clostridium botulinum E3 str. Alaska E43 UviB-like protein YP_001921089.1 1851868 R 508767 CDS YP_001921090.1 188587827 6318608 complement(1852141..1853145) 1 NC_010723.1 identified by match to protein family HMM PF02368; putative phage surface protein 1853145 6318608 CLH_1704 Clostridium botulinum E3 str. Alaska E43 putative phage surface protein YP_001921090.1 1852141 R 508767 CDS YP_001921091.1 188588737 6318466 complement(1853192..1854715) 1 NC_010723.1 identified by match to protein family HMM PF01345; match to protein family HMM PF02368; match to protein family HMM TIGR01451; hypothetical protein 1854715 6318466 CLH_1705 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921091.1 1853192 R 508767 CDS YP_001921092.1 188589213 6317414 complement(1855188..1855385) 1 NC_010723.1 hypothetical protein 1855385 6317414 CLH_1706 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921092.1 1855188 R 508767 CDS YP_001921093.1 188590138 6317773 complement(1855398..1855736) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1855736 6317773 CLH_1707 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921093.1 1855398 R 508767 CDS YP_001921094.1 188588529 6318847 complement(1855752..1857161) 1 NC_010723.1 putative phage tail fiber protein 1857161 6318847 CLH_1708 Clostridium botulinum E3 str. Alaska E43 putative phage tail fiber protein YP_001921094.1 1855752 R 508767 CDS YP_001921095.1 188587621 6318400 complement(1857161..1857823) 1 NC_010723.1 identified by match to protein family HMM PF09684; phage tail protein 1857823 6318400 CLH_1709 Clostridium botulinum E3 str. Alaska E43 phage tail protein YP_001921095.1 1857161 R 508767 CDS YP_001921096.1 188589630 6319415 complement(1857823..1858974) 1 NC_010723.1 identified by match to protein family HMM PF04865; hypothetical protein 1858974 6319415 CLH_1710 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921096.1 1857823 R 508767 CDS YP_001921097.1 188589522 6320106 complement(1858967..1859287) 1 NC_010723.1 putative GPW/gp25 family protein 1859287 6320106 CLH_1711 Clostridium botulinum E3 str. Alaska E43 putative GPW/gp25 family protein YP_001921097.1 1858967 R 508767 CDS YP_001921098.1 188588233 6319269 complement(1859290..1859832) 1 NC_010723.1 hypothetical protein 1859832 6319269 CLH_1712 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921098.1 1859290 R 508767 CDS YP_001921099.1 188590596 6319615 complement(1859837..1860037) 1 NC_010723.1 putative phage baseplate assembly protein V 1860037 6319615 CLH_1713 Clostridium botulinum E3 str. Alaska E43 putative phage baseplate assembly protein V YP_001921099.1 1859837 R 508767 CDS YP_001921100.1 188589206 6318016 complement(1860037..1860945) 1 NC_010723.1 hypothetical protein 1860945 6318016 CLH_1714 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921100.1 1860037 R 508767 CDS YP_001921101.1 188589108 6317683 complement(1860961..1861173) 1 NC_010723.1 hypothetical protein 1861173 6317683 CLH_1715 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921101.1 1860961 R 508767 CDS YP_001921102.1 188587950 6320488 complement(1861166..1863364) 1 NC_010723.1 TMP repeat family 1863364 6320488 CLH_1716 Clostridium botulinum E3 str. Alaska E43 TMP repeat family YP_001921102.1 1861166 R 508767 CDS YP_001921103.1 188589659 6317340 complement(1863530..1863853) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1863853 6317340 CLH_1717 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921103.1 1863530 R 508767 CDS YP_001921104.1 188590580 6320110 complement(1863923..1864444) 1 NC_010723.1 putative phage major tail tube protein 1864444 6320110 CLH_1718 Clostridium botulinum E3 str. Alaska E43 putative phage major tail tube protein YP_001921104.1 1863923 R 508767 CDS YP_001921105.1 188589946 6318112 complement(1864444..1865880) 1 NC_010723.1 hypothetical protein 1865880 6318112 CLH_1719 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921105.1 1864444 R 508767 CDS YP_001921106.1 188589154 6319750 complement(1865893..1866417) 1 NC_010723.1 hypothetical protein 1866417 6319750 CLH_1720 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921106.1 1865893 R 508767 CDS YP_001921107.1 188588234 6319379 complement(1866427..1866999) 1 NC_010723.1 hypothetical protein 1866999 6319379 CLH_1721 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921107.1 1866427 R 508767 CDS YP_001921108.1 188590011 6319618 complement(1866999..1867310) 1 NC_010723.1 hypothetical protein 1867310 6319618 CLH_1722 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921108.1 1866999 R 508767 CDS YP_001921109.1 188589510 6320379 complement(1867300..1867527) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1867527 6320379 CLH_1723 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921109.1 1867300 R 508767 CDS YP_001921110.1 188588631 6319375 complement(1867558..1868604) 1 NC_010723.1 hypothetical protein 1868604 6319375 CLH_1724 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921110.1 1867558 R 508767 CDS YP_001921111.1 188587924 6320588 complement(1868620..1868967) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1868967 6320588 CLH_1725 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921111.1 1868620 R 508767 CDS YP_001921112.1 188589670 6318684 complement(1868967..1870100) 1 NC_010723.1 identified by match to protein family HMM PF00574; peptidase S14, ClpP 1870100 6318684 CLH_1726 Clostridium botulinum E3 str. Alaska E43 peptidase S14, ClpP YP_001921112.1 1868967 R 508767 CDS YP_001921113.1 188588934 6320143 complement(1870180..1871739) 1 NC_010723.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1871739 6320143 CLH_1727 Clostridium botulinum E3 str. Alaska E43 phage portal protein, lambda family YP_001921113.1 1870180 R 508767 CDS YP_001921114.1 188590772 6318958 complement(1871750..1871983) 1 NC_010723.1 hypothetical protein 1871983 6318958 CLH_1728 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921114.1 1871750 R 508767 CDS YP_001921115.1 188590448 6317854 complement(1871999..1873111) 1 NC_010723.1 phage terminase GpA 1873111 6317854 CLH_1729 Clostridium botulinum E3 str. Alaska E43 phage terminase GpA YP_001921115.1 1871999 R 508767 CDS YP_001921116.1 188590313 6317811 complement(1873313..1873819) 1 NC_010723.1 phage terminase GpA 1873819 6317811 CLH_1730 Clostridium botulinum E3 str. Alaska E43 phage terminase GpA YP_001921116.1 1873313 R 508767 CDS YP_001921117.1 188589389 6320448 complement(1873797..1874390) 1 NC_010723.1 hypothetical protein 1874390 6320448 CLH_1731 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921117.1 1873797 R 508767 CDS YP_001921118.1 188588510 6318607 complement(1874657..1875013) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1875013 6318607 CLH_1732 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921118.1 1874657 R 508767 CDS YP_001921119.1 188590125 6318331 complement(1875198..1875782) 1 NC_010723.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 1875782 6318331 CLH_1733 Clostridium botulinum E3 str. Alaska E43 site-specific recombinase, phage integrase family YP_001921119.1 1875198 R 508767 CDS YP_001921120.1 188589970 6320442 complement(1875779..1876006) 1 NC_010723.1 hypothetical protein 1876006 6320442 CLH_1734 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921120.1 1875779 R 508767 CDS YP_001921121.1 188589033 6319035 complement(1876061..1876432) 1 NC_010723.1 gp2 1876432 6319035 CLH_1735 Clostridium botulinum E3 str. Alaska E43 gp2 YP_001921121.1 1876061 R 508767 CDS YP_001921122.1 188588143 6320367 complement(1876560..1876685) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1876685 6320367 CLH_1736 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921122.1 1876560 R 508767 CDS YP_001921123.1 188588015 6317892 complement(1876755..1876904) 1 NC_010723.1 hypothetical protein 1876904 6317892 CLH_1737 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921123.1 1876755 R 508767 CDS YP_001921124.1 188590527 6319482 complement(1877144..1878337) 1 NC_010723.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; thermostable carboxypeptidase 2 1878337 6319482 CLH_1738 Clostridium botulinum E3 str. Alaska E43 thermostable carboxypeptidase 2 YP_001921124.1 1877144 R 508767 CDS YP_001921125.1 188589145 6320289 complement(1878561..1878950) 1 NC_010723.1 hypothetical protein 1878950 6320289 CLH_1739 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921125.1 1878561 R 508767 CDS YP_001921126.1 188589631 6318853 complement(1879101..1879292) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1879292 6318853 CLH_1740 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921126.1 1879101 R 508767 CDS YP_001921127.1 188590177 6320107 complement(1879561..1880067) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1880067 6320107 CLH_1741 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921127.1 1879561 R 508767 CDS YP_001921128.1 188588188 6318295 complement(1880388..1880636) 1 NC_010723.1 identified by match to protein family HMM PF07875; spore coat protein CotF 1880636 6318295 CLH_1742 Clostridium botulinum E3 str. Alaska E43 spore coat protein CotF YP_001921128.1 1880388 R 508767 CDS YP_001921129.1 188587727 6320054 complement(1880649..1880834) 1 NC_010723.1 hypothetical protein 1880834 6320054 CLH_1743 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921129.1 1880649 R 508767 CDS YP_001921130.1 188590350 6318885 complement(1882218..1882403) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1882403 6318885 CLH_1746 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921130.1 1882218 R 508767 CDS YP_001921131.1 188589809 6317407 complement(1882423..1882635) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1882635 6317407 CLH_1747 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921131.1 1882423 R 508767 CDS YP_001921132.1 188589943 6317256 complement(1882754..1883020) 1 NC_010723.1 hypothetical protein 1883020 6317256 CLH_1748 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921132.1 1882754 R 508767 CDS YP_001921133.1 188589089 6319721 1883218..1883544 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1883544 6319721 CLH_1749 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921133.1 1883218 D 508767 CDS YP_001921134.1 188589636 6318762 complement(1883914..1884069) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1884069 6318762 CLH_1750 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921134.1 1883914 R 508767 CDS YP_001921135.1 188590110 6320097 complement(1884066..1884233) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1884233 6320097 CLH_1751 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921135.1 1884066 R 508767 CDS YP_001921136.1 188588241 6317471 complement(1884235..1885176) 1 NC_010723.1 phage protein 1885176 6317471 CLH_1752 Clostridium botulinum E3 str. Alaska E43 phage protein YP_001921136.1 1884235 R 508767 CDS YP_001921137.1 188588679 6319580 complement(1885289..1886437) 1 NC_010723.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; ParB protein 1886437 6319580 CLH_1753 Clostridium botulinum E3 str. Alaska E43 ParB protein YP_001921137.1 1885289 R 508767 CDS YP_001921138.1 188589512 6317507 complement(1886422..1887177) 1 NC_010723.1 identified by match to protein family HMM PF01656; sporulation initiation inhibitor protein soj 1887177 6317507 CLH_1754 Clostridium botulinum E3 str. Alaska E43 sporulation initiation inhibitor protein soj YP_001921138.1 1886422 R 508767 CDS YP_001921139.1 188589609 6317821 complement(1887390..1887563) 1 NC_010723.1 50S ribosomal protein L5 1887563 6317821 CLH_1755 Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L5 YP_001921139.1 1887390 R 508767 CDS YP_001921140.1 188590562 6318887 complement(1887592..1888068) 1 NC_010723.1 hypothetical protein 1888068 6318887 CLH_1756 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921140.1 1887592 R 508767 CDS YP_001921141.1 188589594 6320149 complement(1888190..1888381) 1 NC_010723.1 identified by match to protein family HMM PF01381; hypothetical protein 1888381 6320149 CLH_1757 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921141.1 1888190 R 508767 CDS YP_001921142.1 188590232 6318026 1888558..1888962 1 NC_010723.1 identified by match to protein family HMM PF01381; transcriptional regulator 1888962 6318026 CLH_1758 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001921142.1 1888558 D 508767 CDS YP_001921143.1 188588248 6318257 1889089..1889634 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1889634 6318257 CLH_1759 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921143.1 1889089 D 508767 CDS YP_001921144.1 188588976 6319728 1889748..1889921 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1889921 6319728 CLH_1760 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921144.1 1889748 D 508767 CDS YP_001921145.1 188589486 6319356 complement(1890140..1892179) 1 NC_010723.1 hypothetical protein 1892179 6319356 CLH_1761 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921145.1 1890140 R 508767 CDS YP_001921146.1 188590046 6320573 1892299..1893660 1 NC_010723.1 putative modification methylase 1893660 6320573 CLH_1762 Clostridium botulinum E3 str. Alaska E43 putative modification methylase YP_001921146.1 1892299 D 508767 CDS YP_001921147.1 188587683 6317579 1893711..1895402 1 NC_010723.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; putative resolvase 1895402 6317579 CLH_1763 Clostridium botulinum E3 str. Alaska E43 putative resolvase YP_001921147.1 1893711 D 508767 CDS YP_001921148.1 188589868 6318483 complement(1895452..1895583) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1895583 6318483 CLH_1764 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921148.1 1895452 R 508767 CDS YP_001921149.1 188590482 6319497 complement(1895997..1896278) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1896278 6319497 CLH_1765 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921149.1 1895997 R 508767 CDS YP_001921150.1 188587999 6318270 complement(1896306..1897166) 1 NC_010723.1 identified by match to protein family HMM PF00583; acetyltransferase 1897166 6318270 CLH_1766 Clostridium botulinum E3 str. Alaska E43 acetyltransferase YP_001921150.1 1896306 R 508767 CDS YP_001921151.1 188588993 6320208 complement(1897317..1899224) 1 NC_010723.1 these proteins appear to have resulted from a fusion of lytB and rpsA; catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1899224 6320208 CLH_1767 Clostridium botulinum E3 str. Alaska E43 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001921151.1 1897317 R 508767 CDS YP_001921152.1 188587842 6319438 complement(1899253..1899906) 1 NC_010723.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1899906 cmk 6319438 cmk Clostridium botulinum E3 str. Alaska E43 cytidylate kinase YP_001921152.1 1899253 R 508767 CDS YP_001921153.1 188590114 6317289 complement(1900004..1901224) 1 NC_010723.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275; hypothetical protein 1901224 6317289 CLH_1769 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921153.1 1900004 R 508767 CDS YP_001921154.1 188589205 6317829 complement(1901367..1901594) 1 NC_010723.1 identified by match to protein family HMM PF07866; hypothetical protein 1901594 6317829 CLH_1770 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921154.1 1901367 R 508767 CDS YP_001921155.1 188588614 6317682 complement(1901654..1902301) 1 NC_010723.1 identified by match to protein family HMM PF00805; pentapeptide repeat-containing protein 1902301 6317682 CLH_1771 Clostridium botulinum E3 str. Alaska E43 pentapeptide repeat-containing protein YP_001921155.1 1901654 R 508767 CDS YP_001921156.1 188587763 6317669 complement(1902466..1903668) 1 NC_010723.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR02358; hydroxymethylpyrimidine transporter CytX 1903668 cytX 6317669 cytX Clostridium botulinum E3 str. Alaska E43 hydroxymethylpyrimidine transporter CytX YP_001921156.1 1902466 R 508767 CDS YP_001921157.1 188590651 6319570 complement(1904011..1905042) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1905042 6319570 CLH_1773 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921157.1 1904011 R 508767 CDS YP_001921158.1 188589748 6317913 complement(1905064..1905243) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1905243 6317913 CLH_1774 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921158.1 1905064 R 508767 CDS YP_001921159.1 188587557 6319487 complement(1905388..1906584) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1906584 6319487 CLH_1775 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921159.1 1905388 R 508767 CDS YP_001921160.1 188589710 6319985 complement(1907623..1909521) 1 NC_010723.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02954; signal-transduction and transcriptional-control protein 1909521 6319985 CLH_1778 Clostridium botulinum E3 str. Alaska E43 signal-transduction and transcriptional-control protein YP_001921160.1 1907623 R 508767 CDS YP_001921161.1 188589547 6318283 complement(1909978..1910181) 1 NC_010723.1 hypothetical protein 1910181 6318283 CLH_1779 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921161.1 1909978 R 508767 CDS YP_001921162.1 188588448 6317924 complement(1910503..1911108) 1 NC_010723.1 identified by match to protein family HMM PF00293; nudix-family protein 1911108 6317924 CLH_1780 Clostridium botulinum E3 str. Alaska E43 nudix-family protein YP_001921162.1 1910503 R 508767 CDS YP_001921163.1 188590442 6318883 complement(1911350..1911841) 1 NC_010723.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 1911841 6318883 CLH_1781 Clostridium botulinum E3 str. Alaska E43 ErfK/YbiS/YcfS/YnhG family protein YP_001921163.1 1911350 R 508767 CDS YP_001921164.1 188590251 6318912 complement(1911928..1912701) 1 NC_010723.1 identified by match to protein family HMM PF02811; putative PHP domain 1912701 6318912 CLH_1782 Clostridium botulinum E3 str. Alaska E43 putative PHP domain YP_001921164.1 1911928 R 508767 CDS YP_001921165.1 188589980 6317743 1912874..1913398 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1913398 6317743 CLH_1783 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921165.1 1912874 D 508767 CDS YP_001921166.1 188588776 6319362 complement(1913465..1914106) 1 NC_010723.1 identified by match to protein family HMM PF06571; hypothetical protein 1914106 6319362 CLH_1784 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921166.1 1913465 R 508767 CDS YP_001921167.1 188587718 6317381 1914522..1915178 1 NC_010723.1 putative lipoprotein 1915178 6317381 CLH_1785 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921167.1 1914522 D 508767 CDS YP_001921168.1 188590630 6319126 complement(1915411..1916553) 1 NC_010723.1 FliB family protein 1916553 6319126 CLH_1786 Clostridium botulinum E3 str. Alaska E43 FliB family protein YP_001921168.1 1915411 R 508767 CDS YP_001921169.1 188590409 6319249 complement(1916766..1917077) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1917077 6319249 CLH_1787 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921169.1 1916766 R 508767 CDS YP_001921170.1 188588195 6317251 complement(1917313..1917939) 1 NC_010723.1 hypothetical protein 1917939 6317251 CLH_1788 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921170.1 1917313 R 508767 CDS YP_001921171.1 188590540 6319401 complement(1917943..1918794) 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1918794 6319401 CLH_1789 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001921171.1 1917943 R 508767 CDS YP_001921172.1 188589623 6320181 complement(1918800..1919174) 1 NC_010723.1 identified by match to protein family HMM PF00392; GntR-family transcriptional regulator 1919174 6320181 CLH_1790 Clostridium botulinum E3 str. Alaska E43 GntR-family transcriptional regulator YP_001921172.1 1918800 R 508767 CDS YP_001921173.1 188588881 6318732 complement(1919371..1919628) 1 NC_010723.1 hypothetical protein 1919628 6318732 CLH_1791 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921173.1 1919371 R 508767 CDS YP_001921174.1 188588321 6318989 complement(1919845..1920324) 1 NC_010723.1 identified by match to protein family HMM PF01325; putative iron-dependent repressor 1920324 6318989 CLH_1792 Clostridium botulinum E3 str. Alaska E43 putative iron-dependent repressor YP_001921174.1 1919845 R 508767 CDS YP_001921175.1 188588337 6319964 1920478..1920729 1 NC_010723.1 identified by match to protein family HMM PF04023; hypothetical protein 1920729 6319964 CLH_1793 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921175.1 1920478 D 508767 CDS YP_001921176.1 188590048 6320568 1920804..1922954 1 NC_010723.1 identified by match to protein family HMM PF01926; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; ferrous iron transport protein B 1922954 6320568 CLH_1794 Clostridium botulinum E3 str. Alaska E43 ferrous iron transport protein B YP_001921176.1 1920804 D 508767 CDS YP_001921177.1 188589321 6317575 1923480..1925177 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 1925177 6317575 CLH_1795 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001921177.1 1923480 D 508767 CDS YP_001921178.1 188588568 6317660 complement(1925242..1926060) 1 NC_010723.1 hypothetical protein 1926060 6317660 CLH_1796 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921178.1 1925242 R 508767 CDS YP_001921179.1 188588573 6319145 complement(1926163..1927569) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; two-component sensor histidine kinase 1927569 6319145 CLH_1797 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001921179.1 1926163 R 508767 CDS YP_001921180.1 188589410 6319436 complement(1927571..1928284) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; regulatory protein VanR 1928284 6319436 CLH_1798 Clostridium botulinum E3 str. Alaska E43 regulatory protein VanR YP_001921180.1 1927571 R 508767 CDS YP_001921181.1 188589042 6320445 complement(1928380..1929153) 1 NC_010723.1 ABC transporter permease 1929153 6320445 CLH_1799 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001921181.1 1928380 R 508767 CDS YP_001921182.1 188589364 6319786 complement(1929159..1930046) 1 NC_010723.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1930046 6319786 CLH_1800 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding protein YP_001921182.1 1929159 R 508767 CDS YP_001921183.1 188590022 6319262 complement(1930062..1931087) 1 NC_010723.1 hypothetical protein 1931087 6319262 CLH_1801 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921183.1 1930062 R 508767 CDS YP_001921184.1 188587929 6319541 complement(1931369..1931983) 1 NC_010723.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; superoxide dismutase (Mn) 1931983 6319541 CLH_1802 Clostridium botulinum E3 str. Alaska E43 superoxide dismutase (Mn) YP_001921184.1 1931369 R 508767 CDS YP_001921185.1 188587915 6319022 complement(1932233..1932784) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1932784 6319022 CLH_1803 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921185.1 1932233 R 508767 CDS YP_001921186.1 188588596 6319423 complement(1933421..1933540) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1933540 6319423 CLH_1804 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921186.1 1933421 R 508767 CDS YP_001921187.1 188590667 6319233 complement(1933753..1934970) 1 NC_010723.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1934970 trpB 6319233 trpB Clostridium botulinum E3 str. Alaska E43 tryptophan synthase subunit beta YP_001921187.1 1933753 R 508767 CDS YP_001921188.1 188588307 6318792 complement(1935051..1936592) 1 NC_010723.1 identified by match to protein family HMM PF00580; LexA repressor 1936592 lexA 6318792 lexA Clostridium botulinum E3 str. Alaska E43 LexA repressor YP_001921188.1 1935051 R 508767 CDS YP_001921189.1 188589941 6320002 complement(1936833..1937171) 1 NC_010723.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; alkylphosphonate utilization operon protein PhnA 1937171 phnA 6320002 phnA Clostridium botulinum E3 str. Alaska E43 alkylphosphonate utilization operon protein PhnA YP_001921189.1 1936833 R 508767 CDS YP_001921190.1 188589069 6319844 complement(1937477..1938160) 1 NC_010723.1 identified by match to protein family HMM PF00027; cyclic nucleotide-binding domain-containing protein 1938160 6319844 CLH_1808 Clostridium botulinum E3 str. Alaska E43 cyclic nucleotide-binding domain-containing protein YP_001921190.1 1937477 R 508767 CDS YP_001921191.1 188590210 6320265 1938438..1938968 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1938968 6320265 CLH_1809 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921191.1 1938438 D 508767 CDS YP_001921192.1 188590541 6317300 complement(1939116..1940816) 1 NC_010723.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF02852; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 1940816 6317300 CLH_1810 Clostridium botulinum E3 str. Alaska E43 pyridine nucleotide-disulfide oxidoreductase family protein YP_001921192.1 1939116 R 508767 CDS YP_001921193.1 188587986 6318781 complement(1940901..1941221) 1 NC_010723.1 identified by match to protein family HMM PF00581; rhodanesen domain-containing protein 1941221 6318781 CLH_1811 Clostridium botulinum E3 str. Alaska E43 rhodanesen domain-containing protein YP_001921193.1 1940901 R 508767 CDS YP_001921194.1 188589045 6319015 complement(1941587..1942174) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1942174 6319015 CLH_1812 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921194.1 1941587 R 508767 CDS YP_001921195.1 188590621 6319805 complement(1942614..1943030) 1 NC_010723.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965; transcriptional regulator 1943030 6319805 CLH_1813 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001921195.1 1942614 R 508767 CDS YP_001921196.1 188587652 6318491 complement(1943382..1944521) 1 NC_010723.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-coa dehydrogenase, short-chain specific 1944521 6318491 CLH_1814 Clostridium botulinum E3 str. Alaska E43 acyl-coa dehydrogenase, short-chain specific YP_001921196.1 1943382 R 508767 CDS YP_001921197.1 188588447 6319327 complement(1944701..1946254) 1 NC_010723.1 identified by match to protein family HMM PF01144; propionate CoA-transferase 1946254 6319327 CLH_1815 Clostridium botulinum E3 str. Alaska E43 propionate CoA-transferase YP_001921197.1 1944701 R 508767 CDS YP_001921198.1 188589521 6319590 complement(1946325..1947101) 1 NC_010723.1 identified by match to protein family HMM PF00378; 3-hydroxybutyryl-CoA dehydratase 1947101 6319590 CLH_1816 Clostridium botulinum E3 str. Alaska E43 3-hydroxybutyryl-CoA dehydratase YP_001921198.1 1946325 R 508767 CDS YP_001921199.1 188590528 6319268 complement(1947496..1948323) 1 NC_010723.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 1948323 6319268 CLH_1817 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001921199.1 1947496 R 508767 CDS YP_001921200.1 188589854 6320290 complement(1948747..1949256) 1 NC_010723.1 rubrerythrin family protein 1949256 6320290 CLH_1818 Clostridium botulinum E3 str. Alaska E43 rubrerythrin family protein YP_001921200.1 1948747 R 508767 CDS YP_001921201.1 188588869 6320095 complement(1949448..1950008) 1 NC_010723.1 identified by match to protein family HMM PF00132; O-acetyltransferase family protein 1950008 6320095 CLH_1819 Clostridium botulinum E3 str. Alaska E43 O-acetyltransferase family protein YP_001921201.1 1949448 R 508767 CDS YP_001921202.1 188588333 6318448 1950176..1951051 1 NC_010723.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883; AraC family transcriptional regulator 1951051 6318448 CLH_1820 Clostridium botulinum E3 str. Alaska E43 AraC family transcriptional regulator YP_001921202.1 1950176 D 508767 CDS YP_001921203.1 188590320 6320030 complement(1951131..1951340) 1 NC_010723.1 hypothetical protein 1951340 6320030 CLH_1821 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921203.1 1951131 R 508767 CDS YP_001921204.1 188589406 6320499 1952091..1952339 1 NC_010723.1 hypothetical protein 1952339 6320499 CLH_1822 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921204.1 1952091 D 508767 CDS YP_001921205.1 188588968 6319084 1952406..1953824 1 NC_010723.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain; thiamine biosynthesis protein ThiH 1953824 thiH 6319084 thiH Clostridium botulinum E3 str. Alaska E43 thiamine biosynthesis protein ThiH YP_001921205.1 1952406 D 508767 CDS YP_001921206.1 188588250 6319825 complement(1954533..1954715) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1954715 6319825 CLH_1824 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921206.1 1954533 R 508767 CDS YP_001921207.1 188587572 6319537 1955250..1956818 1 NC_010723.1 identified by match to protein family HMM PF00496; heme-binding protein A 1956818 6319537 CLH_1825 Clostridium botulinum E3 str. Alaska E43 heme-binding protein A YP_001921207.1 1955250 D 508767 CDS YP_001921208.1 188590077 6320335 1956895..1957899 1 NC_010723.1 identified by match to protein family HMM PF00528; dipeptide transport system permease DppB 1957899 6320335 CLH_1826 Clostridium botulinum E3 str. Alaska E43 dipeptide transport system permease DppB YP_001921208.1 1956895 D 508767 CDS YP_001921209.1 188589813 6317243 1957921..1958829 1 NC_010723.1 identified by match to protein family HMM PF00528; glutathione transport system permease protein GsiD 1958829 6317243 CLH_1827 Clostridium botulinum E3 str. Alaska E43 glutathione transport system permease protein GsiD YP_001921209.1 1957921 D 508767 CDS YP_001921210.1 188587975 6320025 1958845..1959819 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide transport ATP-binding protein AppD 1959819 6320025 CLH_1828 Clostridium botulinum E3 str. Alaska E43 oligopeptide transport ATP-binding protein AppD YP_001921210.1 1958845 D 508767 CDS YP_001921211.1 188589404 6317550 1959820..1960797 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide transport ATP-binding protein AppF 1960797 6317550 CLH_1829 Clostridium botulinum E3 str. Alaska E43 oligopeptide transport ATP-binding protein AppF YP_001921211.1 1959820 D 508767 CDS YP_001921212.1 188590312 6319082 1960999..1961361 1 NC_010723.1 identified by match to protein family HMM PF03733; hypothetical protein 1961361 6319082 CLH_1830 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921212.1 1960999 D 508767 CDS YP_001921213.1 188590750 6317523 complement(1961413..1962066) 1 NC_010723.1 identified by match to protein family HMM PF01712; deoxyguanosIne kinase 1962066 6317523 CLH_1831 Clostridium botulinum E3 str. Alaska E43 deoxyguanosIne kinase YP_001921213.1 1961413 R 508767 CDS YP_001921214.1 188588528 6320206 complement(1962226..1962987) 1 NC_010723.1 identified by match to protein family HMM PF02698; GdmH 1962987 6320206 CLH_1832 Clostridium botulinum E3 str. Alaska E43 GdmH YP_001921214.1 1962226 R 508767 CDS YP_001921215.1 188590261 6318399 complement(1963254..1963766) 1 NC_010723.1 hypothetical protein 1963766 6318399 CLH_1833 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921215.1 1963254 R 508767 CDS YP_001921216.1 188589505 6318999 complement(1964271..1964705) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1964705 6318999 CLH_1835 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921216.1 1964271 R 508767 CDS YP_001921217.1 188588399 6318940 complement(1964976..1966283) 1 NC_010723.1 identified by match to protein family HMM PF03553; Na+/H+ antiporter 1966283 6318940 CLH_1836 Clostridium botulinum E3 str. Alaska E43 Na+/H+ antiporter YP_001921217.1 1964976 R 508767 CDS YP_001921218.1 188587673 6319484 complement(1967106..1969328) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 1969328 6319484 CLH_1837 Clostridium botulinum E3 str. Alaska E43 sensor histidine kinase YP_001921218.1 1967106 R 508767 CDS YP_001921219.1 188588155 6318107 complement(1969312..1970019) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; regulatory protein VanR 1970019 6318107 CLH_1838 Clostridium botulinum E3 str. Alaska E43 regulatory protein VanR YP_001921219.1 1969312 R 508767 CDS YP_001921220.1 188588583 6318922 complement(1970405..1970677) 1 NC_010723.1 hypothetical protein 1970677 6318922 CLH_1839 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921220.1 1970405 R 508767 CDS YP_001921221.1 188589715 6320058 complement(1970767..1971168) 1 NC_010723.1 hypothetical protein 1971168 6320058 CLH_1840 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921221.1 1970767 R 508767 CDS YP_001921222.1 188590346 6317706 1971339..1971494 1 NC_010723.1 hypothetical protein 1971494 6317706 CLH_1841 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921222.1 1971339 D 508767 CDS YP_001921223.1 188588317 6317465 complement(1971694..1972218) 1 NC_010723.1 hypothetical protein 1972218 6317465 CLH_1842 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921223.1 1971694 R 508767 CDS YP_001921224.1 188589051 6319971 1972357..1973556 1 NC_010723.1 identified by match to protein family HMM PF02272; match to protein family HMM PF07973; dhha1 domain protein 1973556 6319971 CLH_1843 Clostridium botulinum E3 str. Alaska E43 dhha1 domain protein YP_001921224.1 1972357 D 508767 CDS YP_001921225.1 188588477 6319944 complement(1973753..1974301) 1 NC_010723.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutM 1974301 6319944 CLH_1844 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization protein EutM YP_001921225.1 1973753 R 508767 CDS YP_001921226.1 188589203 6319277 complement(1974326..1975651) 1 NC_010723.1 identified by match to protein family HMM PF01512; ethanolamine utilization Fe-S center protein 1975651 6319277 CLH_1845 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization Fe-S center protein YP_001921226.1 1974326 R 508767 CDS YP_001921227.1 188590535 6317410 complement(1975669..1977162) 1 NC_010723.1 identified by match to protein family HMM PF00171; ethanolamine utilization protein EutE 1977162 6317410 CLH_1846 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization protein EutE YP_001921227.1 1975669 R 508767 CDS YP_001921228.1 188587943 6318100 complement(1977181..1977453) 1 NC_010723.1 identified by match to protein family HMM PF03319; ethanolamine utilization protein EutN 1977453 6318100 CLH_1847 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization protein EutN YP_001921228.1 1977181 R 508767 CDS YP_001921229.1 188589115 6317539 complement(1977463..1978311) 1 NC_010723.1 putative phosphopantothenate--cysteine ligase 1978311 6317539 CLH_1848 Clostridium botulinum E3 str. Alaska E43 putative phosphopantothenate--cysteine ligase YP_001921229.1 1977463 R 508767 CDS YP_001921230.1 188587659 6320554 complement(1978322..1979143) 1 NC_010723.1 identified by match to protein family HMM TIGR02529; ethanolamine utilization protein EutJ 1979143 6320554 CLH_1849 Clostridium botulinum E3 str. Alaska E43 ethanolamine utilization protein EutJ YP_001921230.1 1978322 R 508767 CDS YP_001921231.1 188589905 6319600 complement(1979146..1979802) 1 NC_010723.1 identified by match to protein family HMM PF06130; propanediol utilization protein 1979802 6319600 CLH_1850 Clostridium botulinum E3 str. Alaska E43 propanediol utilization protein YP_001921231.1 1979146 R 508767 CDS YP_001921232.1 188589193 6320518 complement(1979828..1980106) 1 NC_010723.1 identified by match to protein family HMM PF00936; propanediol utilization protein PduA 1980106 6320518 CLH_1851 Clostridium botulinum E3 str. Alaska E43 propanediol utilization protein PduA YP_001921232.1 1979828 R 508767 CDS YP_001921233.1 188589852 6319045 complement(1980211..1980489) 1 NC_010723.1 identified by match to protein family HMM PF00936; propanediol utilization protein PduA 1980489 6319045 CLH_1852 Clostridium botulinum E3 str. Alaska E43 propanediol utilization protein PduA YP_001921233.1 1980211 R 508767 CDS YP_001921234.1 188590556 6320396 complement(1980505..1981005) 1 NC_010723.1 identified by match to protein family HMM PF00936; putative propanediol utilization protein 1981005 6320396 CLH_1853 Clostridium botulinum E3 str. Alaska E43 putative propanediol utilization protein YP_001921234.1 1980505 R 508767 CDS YP_001921235.1 188590404 6318503 complement(1981069..1981893) 1 NC_010723.1 identified by match to protein family HMM PF00936; propanediol utilization protein PduB 1981893 6318503 CLH_1854 Clostridium botulinum E3 str. Alaska E43 propanediol utilization protein PduB YP_001921235.1 1981069 R 508767 CDS YP_001921236.1 188589703 6320039 complement(1982245..1983408) 1 NC_010723.1 identified by match to protein family HMM PF00465; iron-containing alcohol dehydrogenase 1983408 6320039 CLH_1855 Clostridium botulinum E3 str. Alaska E43 iron-containing alcohol dehydrogenase YP_001921236.1 1982245 R 508767 CDS YP_001921237.1 188588969 6317330 complement(1983952..1984257) 1 NC_010723.1 hypothetical protein 1984257 6317330 CLH_1856 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921237.1 1983952 R 508767 CDS YP_001921238.1 188588288 6319658 1984530..1984844 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1984844 6319658 CLH_1857 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921238.1 1984530 D 508767 CDS YP_001921239.1 188587571 6319782 complement(1984952..1986331) 1 NC_010723.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 1986331 6319782 CLH_1858 Clostridium botulinum E3 str. Alaska E43 sodium:dicarboxylate symporter family protein YP_001921239.1 1984952 R 508767 CDS YP_001921240.1 188589646 6318125 complement(1986763..1986996) 1 NC_010723.1 hypothetical protein 1986996 6318125 CLH_1859 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921240.1 1986763 R 508767 CDS YP_001921241.1 188588948 6320080 1987174..1987515 1 NC_010723.1 hypothetical protein 1987515 6320080 CLH_1860 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921241.1 1987174 D 508767 CDS YP_001921242.1 188588151 6318267 complement(1987752..1989710) 1 NC_010723.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03764; match to protein family HMM TIGR00231; tetracycline resistance protein TetP, contain GTP-ase domain 1989710 6318267 CLH_1861 Clostridium botulinum E3 str. Alaska E43 tetracycline resistance protein TetP, contain GTP-ase domain YP_001921242.1 1987752 R 508767 CDS YP_001921243.1 188590755 6319156 complement(1990004..1991119) 1 NC_010723.1 identified by match to protein family HMM PF00561; lysophospholipase l2 pldb, hydrolase of alpha/beta superfamily 1991119 6319156 CLH_1862 Clostridium botulinum E3 str. Alaska E43 lysophospholipase l2 pldb, hydrolase of alpha/beta superfamily YP_001921243.1 1990004 R 508767 CDS YP_001921244.1 188589202 6319116 complement(1991170..1991511) 1 NC_010723.1 hypothetical protein 1991511 6319116 CLH_1863 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921244.1 1991170 R 508767 CDS YP_001921245.1 188588613 6317409 complement(1991543..1992298) 1 NC_010723.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1992298 xth 6317409 xth Clostridium botulinum E3 str. Alaska E43 exodeoxyribonuclease III YP_001921245.1 1991543 R 508767 CDS YP_001921246.1 188587946 6318037 complement(1992595..1992882) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 1992882 6318037 CLH_1865 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921246.1 1992595 R 508767 CDS YP_001921247.1 188590198 6320552 complement(1993307..1995313) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; membrane associated methyl-accepting chemotaxis protein 1995313 6320552 CLH_1866 Clostridium botulinum E3 str. Alaska E43 membrane associated methyl-accepting chemotaxis protein YP_001921247.1 1993307 R 508767 CDS YP_001921248.1 188589669 6317715 complement(1995551..1997527) 1 NC_010723.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497; hypothetical protein 1997527 6317715 CLH_1867 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921248.1 1995551 R 508767 CDS YP_001921249.1 188589134 6320136 complement(1997789..1998658) 1 NC_010723.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 1998658 6320136 CLH_1868 Clostridium botulinum E3 str. Alaska E43 DegV family protein YP_001921249.1 1997789 R 508767 CDS YP_001921250.1 188590043 6318477 complement(1999155..2000096) 1 NC_010723.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating protein family 2000096 6318477 CLH_1869 Clostridium botulinum E3 str. Alaska E43 glycyl-radical enzyme activating protein family YP_001921250.1 1999155 R 508767 CDS YP_001921251.1 188590595 6320340 complement(2000132..2001400) 1 NC_010723.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2001400 6320340 CLH_1870 Clostridium botulinum E3 str. Alaska E43 major facilitator family transporter YP_001921251.1 2000132 R 508767 CDS YP_001921252.1 188589496 6318015 complement(2001552..2001821) 1 NC_010723.1 4-hydroxyphenylacetate decarboxylase, regulatory subunit 2001821 6318015 CLH_1871 Clostridium botulinum E3 str. Alaska E43 4-hydroxyphenylacetate decarboxylase, regulatory subunit YP_001921252.1 2001552 R 508767 CDS YP_001921253.1 188589129 6319391 complement(2001828..2004545) 1 NC_010723.1 identified by match to protein family HMM PF02901; 4-hydroxyphenylacetate decarboxylase, catalytic subunit 2004545 6319391 CLH_1872 Clostridium botulinum E3 str. Alaska E43 4-hydroxyphenylacetate decarboxylase, catalytic subunit YP_001921253.1 2001828 R 508767 CDS YP_001921254.1 188588025 6318772 complement(2004826..2005734) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01966; match to protein family HMM TIGR00277; metal dependent phosphohydrolase, HD region with Response Regulator Receiver modulation 2005734 6318772 CLH_1873 Clostridium botulinum E3 str. Alaska E43 metal dependent phosphohydrolase, HD region with Response Regulator Receiver modulation YP_001921254.1 2004826 R 508767 CDS YP_001921255.1 188588291 6319288 complement(2005763..2007808) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; Two component system histidine kinase 2007808 6319288 CLH_1874 Clostridium botulinum E3 str. Alaska E43 Two component system histidine kinase YP_001921255.1 2005763 R 508767 CDS YP_001921256.1 188590713 6319770 complement(2007819..2008550) 1 NC_010723.1 identified by match to protein family HMM PF00196; match to protein family HMM PF08281; sigma-70, region 4 family 2008550 6319770 CLH_1875 Clostridium botulinum E3 str. Alaska E43 sigma-70, region 4 family YP_001921256.1 2007819 R 508767 CDS YP_001921257.1 188588402 6318788 complement(2008840..2010555) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis sensory transducer 2010555 6318788 CLH_1876 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis sensory transducer YP_001921257.1 2008840 R 508767 CDS YP_001921258.1 188587697 6320606 complement(2010657..2011670) 1 NC_010723.1 identified by match to protein family HMM PF01547; periplasmic-iron-binding protein BitA 2011670 6320606 CLH_1877 Clostridium botulinum E3 str. Alaska E43 periplasmic-iron-binding protein BitA YP_001921258.1 2010657 R 508767 CDS YP_001921259.1 188587700 6318948 complement(2012089..2014077) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; putative methyl-accepting chemotaxis protein 2014077 6318948 CLH_1878 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis protein YP_001921259.1 2012089 R 508767 CDS YP_001921260.1 188588036 6318956 complement(2014318..2015673) 1 NC_010723.1 identified by match to protein family HMM PF05167; hypothetical protein 2015673 6318956 CLH_1879 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921260.1 2014318 R 508767 CDS YP_001921261.1 188589192 6318245 complement(2015688..2015957) 1 NC_010723.1 ACT domain-containing protein; hypothetical protein 2015957 6318245 CLH_1880 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921261.1 2015688 R 508767 CDS YP_001921262.1 188590133 6317288 complement(2016126..2018345) 1 NC_010723.1 putative cell wall anchored protein 2018345 6317288 CLH_1881 Clostridium botulinum E3 str. Alaska E43 putative cell wall anchored protein YP_001921262.1 2016126 R 508767 CDS YP_001921263.1 188588988 6317344 complement(2018367..2019617) 1 NC_010723.1 identified by match to protein family HMM PF00535; N-acetylglucosaminyltransferase 2019617 6317344 CLH_1882 Clostridium botulinum E3 str. Alaska E43 N-acetylglucosaminyltransferase YP_001921263.1 2018367 R 508767 CDS YP_001921264.1 188588271 6319304 complement(2019629..2020984) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2020984 6319304 CLH_1883 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921264.1 2019629 R 508767 CDS YP_001921265.1 188590504 6319827 complement(2020968..2021822) 1 NC_010723.1 putative signaling protein 2021822 6319827 CLH_1884 Clostridium botulinum E3 str. Alaska E43 putative signaling protein YP_001921265.1 2020968 R 508767 CDS YP_001921266.1 188589849 6317998 complement(2021837..2023324) 1 NC_010723.1 putative transmembrane protein 2023324 6317998 CLH_1885 Clostridium botulinum E3 str. Alaska E43 putative transmembrane protein YP_001921266.1 2021837 R 508767 CDS YP_001921267.1 188589210 6319460 complement(2023684..2024187) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2024187 6319460 CLH_1886 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921267.1 2023684 R 508767 CDS YP_001921268.1 188588997 6317649 complement(2024270..2024446) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2024446 6317649 CLH_1887 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921268.1 2024270 R 508767 CDS YP_001921269.1 188587784 6319621 complement(2024579..2025088) 1 NC_010723.1 identified by match to protein family HMM PF06177; citrulline cluster-linked gene 2025088 6319621 CLH_1888 Clostridium botulinum E3 str. Alaska E43 citrulline cluster-linked gene YP_001921269.1 2024579 R 508767 CDS YP_001921270.1 188588217 6317863 complement(2025676..2026665) 1 NC_010723.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 2026665 galE 6317863 galE Clostridium botulinum E3 str. Alaska E43 UDP-glucose 4-epimerase YP_001921270.1 2025676 R 508767 CDS YP_001921271.1 188590571 6319670 complement(2026812..2027489) 1 NC_010723.1 identified by match to protein family HMM PF04607; GTP-pyrophosphokinase 2027489 6319670 CLH_1890 Clostridium botulinum E3 str. Alaska E43 GTP-pyrophosphokinase YP_001921271.1 2026812 R 508767 CDS YP_001921272.1 188588713 6317876 2027696..2029051 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02906; [Fe] hydrogenase 2029051 6317876 CLH_1891 Clostridium botulinum E3 str. Alaska E43 [Fe] hydrogenase YP_001921272.1 2027696 D 508767 CDS YP_001921273.1 188587753 6317757 2029398..2031443 1 NC_010723.1 identified by match to protein family HMM PF00395; match to protein family HMM PF03413; putative propeptide, PepSY amd peptidase M4 2031443 6317757 CLH_1892 Clostridium botulinum E3 str. Alaska E43 putative propeptide, PepSY amd peptidase M4 YP_001921273.1 2029398 D 508767 CDS YP_001921274.1 188587771 6319319 complement(2031766..2032245) 1 NC_010723.1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated; methylated-DNA--protein-cysteine methyltransferase 2032245 6319319 CLH_1893 Clostridium botulinum E3 str. Alaska E43 methylated-DNA--protein-cysteine methyltransferase YP_001921274.1 2031766 R 508767 CDS YP_001921275.1 188590293 6319878 complement(2032281..2033093) 1 NC_010723.1 identified by match to protein family HMM PF00896; match to protein family HMM TIGR01697; match to protein family HMM TIGR01700; purine nucleoside phosphorylase I 2033093 6319878 CLH_1894 Clostridium botulinum E3 str. Alaska E43 purine nucleoside phosphorylase I YP_001921275.1 2032281 R 508767 CDS YP_001921276.1 188589972 6318765 complement(2033164..2034378) 1 NC_010723.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2034378 tyrS 6318765 tyrS Clostridium botulinum E3 str. Alaska E43 tyrosyl-tRNA synthetase YP_001921276.1 2033164 R 508767 CDS YP_001921277.1 188589094 6319163 complement(2035477..2036772) 1 NC_010723.1 identified by match to protein family HMM PF01979; amidohydrolase 2036772 6319163 CLH_1896 Clostridium botulinum E3 str. Alaska E43 amidohydrolase YP_001921277.1 2035477 R 508767 CDS YP_001921278.1 188589531 6318170 complement(2037177..2040617) 1 NC_010723.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 2040617 pyc 6318170 pyc Clostridium botulinum E3 str. Alaska E43 pyruvate carboxylase YP_001921278.1 2037177 R 508767 CDS YP_001921279.1 188589615 6320300 complement(2041410..2042783) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 2042783 6320300 CLH_1898 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001921279.1 2041410 R 508767 CDS YP_001921280.1 188589150 6317886 complement(2043149..2043721) 1 NC_010723.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 2043721 xpt 6317886 xpt Clostridium botulinum E3 str. Alaska E43 xanthine phosphoribosyltransferase YP_001921280.1 2043149 R 508767 CDS YP_001921281.1 188589864 6319026 complement(2043724..2045088) 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 2045088 6319026 CLH_1900 Clostridium botulinum E3 str. Alaska E43 xanthine permease YP_001921281.1 2043724 R 508767 CDS YP_001921282.1 188589305 6320536 complement(2045424..2046611) 1 NC_010723.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2046611 6320536 CLH_1901 Clostridium botulinum E3 str. Alaska E43 major facilitator family transporter YP_001921282.1 2045424 R 508767 CDS YP_001921283.1 188590149 6317277 complement(2047132..2048502) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 2048502 6317277 CLH_1902 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001921283.1 2047132 R 508767 CDS YP_001921284.1 188589009 6317726 complement(2048772..2051696) 1 NC_010723.1 identified by match to protein family HMM PF00929; putative exonuclease 2051696 6317726 CLH_1903 Clostridium botulinum E3 str. Alaska E43 putative exonuclease YP_001921284.1 2048772 R 508767 CDS YP_001921285.1 188589596 6319464 complement(2051706..2051852) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2051852 6319464 CLH_1904 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921285.1 2051706 R 508767 CDS YP_001921286.1 188590544 6319380 complement(2052201..2052452) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2052452 6319380 CLH_1905 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921286.1 2052201 R 508767 CDS YP_001921287.1 188587797 6317961 complement(2052547..2052738) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2052738 6317961 CLH_1906 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921287.1 2052547 R 508767 CDS YP_001921288.1 188588484 6319446 complement(2052787..2053284) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2053284 6319446 CLH_1907 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921288.1 2052787 R 508767 CDS YP_001921289.1 188589395 6320308 complement(2053388..2054458) 1 NC_010723.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01714; N- phage replisome organizer 2054458 6320308 CLH_1908 Clostridium botulinum E3 str. Alaska E43 N- phage replisome organizer YP_001921289.1 2053388 R 508767 CDS YP_001921290.1 188589725 6318654 complement(2054918..2055586) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2055586 6318654 CLH_1909 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921290.1 2054918 R 508767 CDS YP_001921291.1 188587542 6318211 2055901..2056179 1 NC_010723.1 hypothetical protein 2056179 6318211 CLH_1910 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921291.1 2055901 D 508767 CDS YP_001921292.1 188590089 6318651 2056456..2057118 1 NC_010723.1 identified by match to protein family HMM PF07299; putative fibronectin-binding protein 2057118 6318651 CLH_1911 Clostridium botulinum E3 str. Alaska E43 putative fibronectin-binding protein YP_001921292.1 2056456 D 508767 CDS YP_001921293.1 188587859 6317616 complement(2057330..2057578) 1 NC_010723.1 hypothetical protein 2057578 6317616 CLH_1912 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921293.1 2057330 R 508767 CDS YP_001921294.1 188590096 6317430 complement(2057692..2059272) 1 NC_010723.1 alpha/beta superfamily hydrolase 2059272 6317430 CLH_1913 Clostridium botulinum E3 str. Alaska E43 alpha/beta superfamily hydrolase YP_001921294.1 2057692 R 508767 CDS YP_001921295.1 188589283 6317379 complement(2059451..2060857) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; hypothetical protein 2060857 6317379 CLH_1914 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921295.1 2059451 R 508767 CDS YP_001921296.1 188588979 6317724 complement(2060866..2061567) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulatory protein ResD 2061567 6317724 CLH_1915 Clostridium botulinum E3 str. Alaska E43 transcriptional regulatory protein ResD YP_001921296.1 2060866 R 508767 CDS YP_001921297.1 188588286 6319463 complement(2061879..2062532) 1 NC_010723.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428; CoA-transferase subunit B 2062532 6319463 CLH_1916 Clostridium botulinum E3 str. Alaska E43 CoA-transferase subunit B YP_001921297.1 2061879 R 508767 CDS YP_001921298.1 188590419 6319799 complement(2062546..2063262) 1 NC_010723.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429; CoA-transferase subunit A 2063262 6319799 CLH_1917 Clostridium botulinum E3 str. Alaska E43 CoA-transferase subunit A YP_001921298.1 2062546 R 508767 CDS YP_001921299.1 188587824 6318545 complement(2063796..2065472) 1 NC_010723.1 identified by match to protein family HMM PF08011; hypothetical protein 2065472 6318545 CLH_1918 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921299.1 2063796 R 508767 CDS YP_001921300.1 188590548 6319184 complement(2065585..2066046) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2066046 6319184 CLH_1919 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921300.1 2065585 R 508767 CDS YP_001921301.1 188589768 6317983 complement(2066022..2066783) 1 NC_010723.1 hypothetical protein 2066783 6317983 CLH_1920 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921301.1 2066022 R 508767 CDS YP_001921302.1 188588625 6319729 complement(2067038..2067598) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2067598 6319729 CLH_1921 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921302.1 2067038 R 508767 CDS YP_001921303.1 188589479 6317704 complement(2067610..2067774) 1 NC_010723.1 filamentation induced by cAMP protein fic 2067774 6317704 CLH_1922 Clostridium botulinum E3 str. Alaska E43 filamentation induced by cAMP protein fic YP_001921303.1 2067610 R 508767 CDS YP_001921304.1 188587554 6318582 2068299..2069387 1 NC_010723.1 identified by match to protein family HMM TIGR03187; match to protein family HMM TIGR03233; DNA sulfur modification protein DndB 2069387 dndB 6318582 dndB Clostridium botulinum E3 str. Alaska E43 DNA sulfur modification protein DndB YP_001921304.1 2068299 D 508767 CDS YP_001921305.1 188590327 6317932 2069387..2071015 1 NC_010723.1 identified by match to protein family HMM TIGR03183; hypothetical protein 2071015 dndC 6317932 dndC Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921305.1 2069387 D 508767 CDS YP_001921306.1 188588958 6319039 2071005..2073164 1 NC_010723.1 identified by match to protein family HMM TIGR03185; DNA sulfur modification protein DndD 2073164 dndD 6319039 dndD Clostridium botulinum E3 str. Alaska E43 DNA sulfur modification protein DndD YP_001921306.1 2071005 D 508767 CDS YP_001921307.1 188588488 6317478 2073167..2073556 1 NC_010723.1 hypothetical protein 2073556 6317478 CLH_1926 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921307.1 2073167 D 508767 CDS YP_001921308.1 188588725 6320153 2073553..2074749 1 NC_010723.1 identified by match to protein family HMM PF00266; cysteine desulfurase 2074749 6320153 CLH_1927 Clostridium botulinum E3 str. Alaska E43 cysteine desulfurase YP_001921308.1 2073553 D 508767 CDS YP_001921309.1 188589509 6317678 complement(2074753..2075529) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2075529 6317678 CLH_1928 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921309.1 2074753 R 508767 CDS YP_001921310.1 188588391 6317839 complement(2075577..2077373) 1 NC_010723.1 identified by match to protein family HMM PF03235; match to protein family HMM PF07510; hypothetical protein 2077373 6317839 CLH_1929 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921310.1 2075577 R 508767 CDS YP_001921311.1 188587807 6319829 complement(2077508..2082769) 1 NC_010723.1 hypothetical protein 2082769 6319829 CLH_1930 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921311.1 2077508 R 508767 CDS YP_001921312.1 188590561 6319499 complement(2082750..2084165) 1 NC_010723.1 hypothetical protein 2084165 6319499 CLH_1931 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921312.1 2082750 R 508767 CDS YP_001921313.1 188589957 6320148 complement(2084165..2086567) 1 NC_010723.1 hypothetical protein 2086567 6320148 CLH_1932 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921313.1 2084165 R 508767 CDS YP_001921314.1 188588816 6317881 complement(2086875..2087999) 1 NC_010723.1 hypothetical protein 2087999 6317881 CLH_1933 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921314.1 2086875 R 508767 CDS YP_001921315.1 188590383 6320292 complement(2088247..2088957) 1 NC_010723.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 2088957 6320292 CLH_1934 Clostridium botulinum E3 str. Alaska E43 glycerol uptake facilitator protein YP_001921315.1 2088247 R 508767 CDS YP_001921316.1 188589466 6318644 complement(2089091..2090248) 1 NC_010723.1 identified by match to protein family HMM PF00465; 1,3-propanediol dehydrogenase 2090248 dhaT 6318644 dhaT Clostridium botulinum E3 str. Alaska E43 1,3-propanediol dehydrogenase YP_001921316.1 2089091 R 508767 CDS YP_001921317.1 188590374 6320356 complement(2090383..2090808) 1 NC_010723.1 identified by match to protein family HMM PF03928; DhaG protein 2090808 6320356 CLH_1936 Clostridium botulinum E3 str. Alaska E43 DhaG protein YP_001921317.1 2090383 R 508767 CDS YP_001921318.1 188589368 6320485 complement(2090826..2091338) 1 NC_010723.1 identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; ATP:cob(I)alamin adenosyltransferase 2091338 6320485 CLH_1937 Clostridium botulinum E3 str. Alaska E43 ATP:cob(I)alamin adenosyltransferase YP_001921318.1 2090826 R 508767 CDS YP_001921319.1 188588782 6319266 complement(2091360..2091719) 1 NC_010723.1 glycerol dehydratase reactivation factor, small subunit 2091719 6319266 CLH_1938 Clostridium botulinum E3 str. Alaska E43 glycerol dehydratase reactivation factor, small subunit YP_001921319.1 2091360 R 508767 CDS YP_001921320.1 188589918 6318368 complement(2091719..2093557) 1 NC_010723.1 identified by match to protein family HMM PF08841; glycerol dehydratase reactivation factor large subunit 2093557 6318368 CLH_1939 Clostridium botulinum E3 str. Alaska E43 glycerol dehydratase reactivation factor large subunit YP_001921320.1 2091719 R 508767 CDS YP_001921321.1 188590615 6320397 complement(2093585..2094007) 1 NC_010723.1 identified by match to protein family HMM PF02287; coenzyme B12-dependent glycerol dehydratase, small subunit 2094007 6320397 CLH_1940 Clostridium botulinum E3 str. Alaska E43 coenzyme B12-dependent glycerol dehydratase, small subunit YP_001921321.1 2093585 R 508767 CDS YP_001921322.1 188590348 6320237 complement(2094029..2094604) 1 NC_010723.1 identified by match to protein family HMM PF02288; propanediol utilization: dehydratase, medium subunit 2094604 6320237 CLH_1941 Clostridium botulinum E3 str. Alaska E43 propanediol utilization: dehydratase, medium subunit YP_001921322.1 2094029 R 508767 CDS YP_001921323.1 188587878 6317405 complement(2094622..2096286) 1 NC_010723.1 identified by match to protein family HMM PF02286; coenzyme B12-dependent glycerol dehydratase, large subunit 2096286 6317405 CLH_1942 Clostridium botulinum E3 str. Alaska E43 coenzyme B12-dependent glycerol dehydratase, large subunit YP_001921323.1 2094622 R 508767 CDS YP_001921324.1 188588582 6319617 complement(2096601..2097335) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; AraC family transcriptional regulator 2097335 6319617 CLH_1943 Clostridium botulinum E3 str. Alaska E43 AraC family transcriptional regulator YP_001921324.1 2096601 R 508767 CDS YP_001921325.1 188589724 6318305 complement(2097351..2098592) 1 NC_010723.1 identified by match to protein family HMM PF02518; match to protein family HMM PF06580; sensor histidine kinase 2098592 6318305 CLH_1944 Clostridium botulinum E3 str. Alaska E43 sensor histidine kinase YP_001921325.1 2097351 R 508767 CDS YP_001921326.1 188588953 6318210 2098943..2102257 1 NC_010723.1 identified by match to protein family HMM PF01473; match to protein family HMM PF07554; hypothetical protein 2102257 6318210 CLH_1945 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921326.1 2098943 D 508767 CDS YP_001921327.1 188588067 6320530 complement(2102385..2103527) 1 NC_010723.1 identified by match to protein family HMM PF04326; divergent AAA domain family 2103527 6320530 CLH_1946 Clostridium botulinum E3 str. Alaska E43 divergent AAA domain family YP_001921327.1 2102385 R 508767 CDS YP_001921328.1 188588440 6318745 complement(2103690..2103977) 1 NC_010723.1 identified by match to protein family HMM PF01909; DNA polymerase, beta domain-containing protein region 2103977 6318745 CLH_1947 Clostridium botulinum E3 str. Alaska E43 DNA polymerase, beta domain-containing protein region YP_001921328.1 2103690 R 508767 CDS YP_001921329.1 188589500 6319795 complement(2103983..2104420) 1 NC_010723.1 identified by match to protein family HMM PF08780; match to protein family HMM TIGR01987; putative nucleotidyltransferase substrate binding protein 2104420 6319795 CLH_1948 Clostridium botulinum E3 str. Alaska E43 putative nucleotidyltransferase substrate binding protein YP_001921329.1 2103983 R 508767 CDS YP_001921330.1 188590200 6318951 2104673..2105524 1 NC_010723.1 identified by match to protein family HMM PF00248; morphine 6-dehydrogenase 2105524 6318951 CLH_1949 Clostridium botulinum E3 str. Alaska E43 morphine 6-dehydrogenase YP_001921330.1 2104673 D 508767 CDS YP_001921331.1 188590552 6317655 complement(2106091..2106876) 1 NC_010723.1 identified by match to protein family HMM PF00005; ferric enterobactin transport ATP-binding protein FepC 2106876 6317655 CLH_1950 Clostridium botulinum E3 str. Alaska E43 ferric enterobactin transport ATP-binding protein FepC YP_001921331.1 2106091 R 508767 CDS YP_001921332.1 188587956 6318816 complement(2106911..2107927) 1 NC_010723.1 identified by match to protein family HMM PF01032; ferrichrome transport system permease FhuG 2107927 6318816 CLH_1951 Clostridium botulinum E3 str. Alaska E43 ferrichrome transport system permease FhuG YP_001921332.1 2106911 R 508767 CDS YP_001921333.1 188589104 6317272 complement(2107928..2108941) 1 NC_010723.1 identified by match to protein family HMM PF01032; ferrichrome transport system permease FhuB 2108941 6317272 CLH_1952 Clostridium botulinum E3 str. Alaska E43 ferrichrome transport system permease FhuB YP_001921333.1 2107928 R 508767 CDS YP_001921334.1 188589843 6320563 complement(2109030..2109971) 1 NC_010723.1 identified by match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 2109971 6320563 CLH_1953 Clostridium botulinum E3 str. Alaska E43 iron compound ABC transporter iron compound-binding protein YP_001921334.1 2109030 R 508767 CDS YP_001921335.1 188590036 6320129 complement(2110147..2110308) 1 NC_010723.1 hypothetical protein 2110308 6320129 CLH_1954 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921335.1 2110147 R 508767 CDS YP_001921336.1 188587799 6318314 complement(2110574..2112004) 1 NC_010723.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system, glucose-like IIB component 2112004 6318314 CLH_1955 Clostridium botulinum E3 str. Alaska E43 PTS system, glucose-like IIB component YP_001921336.1 2110574 R 508767 CDS YP_001921337.1 188588697 6317889 complement(2112023..2113696) 1 NC_010723.1 identified by match to protein family HMM PF00128; oligo-1,6-glucosidase 2113696 6317889 CLH_1956 Clostridium botulinum E3 str. Alaska E43 oligo-1,6-glucosidase YP_001921337.1 2112023 R 508767 CDS YP_001921338.1 188588807 6318659 complement(2113707..2114552) 1 NC_010723.1 identified by match to protein family HMM PF08282; match to protein family HMM TIGR01484; putative hydrolase 2114552 6318659 CLH_1957 Clostridium botulinum E3 str. Alaska E43 putative hydrolase YP_001921338.1 2113707 R 508767 CDS YP_001921339.1 188588065 6318117 complement(2114659..2115435) 1 NC_010723.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 2115435 6318117 CLH_1958 Clostridium botulinum E3 str. Alaska E43 RpiR family transcriptional regulator YP_001921339.1 2114659 R 508767 CDS YP_001921340.1 188590288 6318743 complement(2115432..2116190) 1 NC_010723.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 2116190 6318743 CLH_1959 Clostridium botulinum E3 str. Alaska E43 RpiR family transcriptional regulator YP_001921340.1 2115432 R 508767 CDS YP_001921341.1 188589506 6318004 complement(2116219..2116533) 1 NC_010723.1 membrane spanning protein 2116533 6318004 CLH_1960 Clostridium botulinum E3 str. Alaska E43 membrane spanning protein YP_001921341.1 2116219 R 508767 CDS YP_001921342.1 188588363 6318941 2116843..2117388 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2117388 6318941 CLH_1961 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921342.1 2116843 D 508767 CDS YP_001921343.1 188587644 6320012 2117547..2118218 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2118218 6320012 CLH_1962 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921343.1 2117547 D 508767 CDS YP_001921344.1 188590388 6319605 complement(2118299..2119519) 1 NC_010723.1 FliB family protein 2119519 6319605 CLH_1963 Clostridium botulinum E3 str. Alaska E43 FliB family protein YP_001921344.1 2118299 R 508767 CDS YP_001921345.1 188589525 6320466 complement(2119543..2120022) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2120022 6320466 CLH_1964 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921345.1 2119543 R 508767 CDS YP_001921346.1 188588406 6320287 2120317..2120631 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2120631 6320287 CLH_1965 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921346.1 2120317 D 508767 CDS YP_001921347.1 188587699 6319334 complement(2120720..2120989) 1 NC_010723.1 hypothetical protein 2120989 6319334 CLH_1966 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921347.1 2120720 R 508767 CDS YP_001921348.1 188588549 6318955 complement(2121001..2121291) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2121291 6318955 CLH_1967 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921348.1 2121001 R 508767 CDS YP_001921349.1 188587634 6318360 complement(2121457..2122071) 1 NC_010723.1 hypothetical protein 2122071 6318360 CLH_1968 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921349.1 2121457 R 508767 CDS YP_001921350.1 188590718 6319863 complement(2122278..2123108) 1 NC_010723.1 identified by match to protein family HMM PF00149; phosphoesterase 2123108 6319863 CLH_1969 Clostridium botulinum E3 str. Alaska E43 phosphoesterase YP_001921350.1 2122278 R 508767 CDS YP_001921351.1 188589886 6320200 complement(2123162..2123563) 1 NC_010723.1 identified by match to protein family HMM PF00903; glyoxalase/bleomycin resistance protein/dioxygenase 2123563 6320200 CLH_1970 Clostridium botulinum E3 str. Alaska E43 glyoxalase/bleomycin resistance protein/dioxygenase YP_001921351.1 2123162 R 508767 CDS YP_001921352.1 188587733 6319232 complement(2123603..2124676) 1 NC_010723.1 identified by match to protein family HMM PF02016; bacteriocin immunity protein 2124676 6319232 CLH_1971 Clostridium botulinum E3 str. Alaska E43 bacteriocin immunity protein YP_001921352.1 2123603 R 508767 CDS YP_001921353.1 188588696 6318718 complement(2124756..2124911) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2124911 6318718 CLH_1972 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921353.1 2124756 R 508767 CDS YP_001921354.1 188589209 6318658 complement(2124980..2125531) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2125531 6318658 CLH_1973 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921354.1 2124980 R 508767 CDS YP_001921355.1 188590141 6317634 complement(2125609..2126037) 1 NC_010723.1 identified by match to protein family HMM PF05014; nucleoside 2-deoxyribosyltransferase 2126037 6317634 CLH_1974 Clostridium botulinum E3 str. Alaska E43 nucleoside 2-deoxyribosyltransferase YP_001921355.1 2125609 R 508767 CDS YP_001921356.1 188590307 6317258 complement(2126180..2126773) 1 NC_010723.1 identified by match to protein family HMM PF00132; maltose O-acetyltransferase 2126773 6317258 CLH_1975 Clostridium botulinum E3 str. Alaska E43 maltose O-acetyltransferase YP_001921356.1 2126180 R 508767 CDS YP_001921357.1 188587561 6318517 complement(2126977..2128713) 1 NC_010723.1 identified by match to protein family HMM PF05569; peptidase, M56 family protein 2128713 6318517 CLH_1976 Clostridium botulinum E3 str. Alaska E43 peptidase, M56 family protein YP_001921357.1 2126977 R 508767 CDS YP_001921358.1 188589539 6319551 complement(2128710..2129093) 1 NC_010723.1 identified by match to protein family HMM PF03965; penicillinase repressor 2129093 6319551 CLH_1977 Clostridium botulinum E3 str. Alaska E43 penicillinase repressor YP_001921358.1 2128710 R 508767 CDS YP_001921359.1 188590382 6319286 complement(2129377..2129499) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2129499 6319286 CLH_1978 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921359.1 2129377 R 508767 CDS YP_001921360.1 188587662 6320363 complement(2129586..2130008) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2130008 6320363 CLH_1979 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921360.1 2129586 R 508767 CDS YP_001921361.1 188589133 6319558 2130183..2130392 1 NC_010723.1 identified by match to protein family HMM PF01381; hypothetical protein 2130392 6319558 CLH_1980 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921361.1 2130183 D 508767 CDS YP_001921362.1 188589530 6318476 2130385..2130852 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2130852 6318476 CLH_1981 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921362.1 2130385 D 508767 CDS YP_001921363.1 188590391 6318115 complement(2130889..2131020) 1 NC_010723.1 hydrolase, isochorismatase family 2131020 6318115 CLH_1982 Clostridium botulinum E3 str. Alaska E43 hydrolase, isochorismatase family YP_001921363.1 2130889 R 508767 CDS YP_001921364.1 188590407 6317546 complement(2131067..2131579) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2131579 6317546 CLH_1983 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921364.1 2131067 R 508767 CDS YP_001921365.1 188588819 6317608 complement(2131852..2131977) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2131977 6317608 CLH_1984 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921365.1 2131852 R 508767 CDS YP_001921366.1 188589780 6317978 complement(2132043..2132483) 1 NC_010723.1 identified by match to protein family HMM PF00583; acetyltransferase 2132483 6317978 CLH_1985 Clostridium botulinum E3 str. Alaska E43 acetyltransferase YP_001921366.1 2132043 R 508767 CDS YP_001921367.1 188590739 6318063 complement(2132538..2132882) 1 NC_010723.1 hypothetical protein 2132882 6318063 CLH_1986 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921367.1 2132538 R 508767 CDS YP_001921368.1 188590156 6319272 complement(2133366..2133833) 1 NC_010723.1 hypothetical protein 2133833 6319272 CLH_1987 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921368.1 2133366 R 508767 CDS YP_001921369.1 188589013 6317987 2134131..2134457 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2134457 6317987 CLH_1988 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921369.1 2134131 D 508767 CDS YP_001921370.1 188588274 6318226 complement(2134640..2135743) 1 NC_010723.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 2135743 6318226 CLH_1989 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001921370.1 2134640 R 508767 CDS YP_001921371.1 188590486 6319817 complement(2135994..2136536) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2136536 6319817 CLH_1990 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921371.1 2135994 R 508767 CDS YP_001921372.1 188589666 6318882 2136781..2137062 1 NC_010723.1 identified by match to protein family HMM PF01022; transcriptional regulator ArsR family 2137062 6318882 CLH_1991 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator ArsR family YP_001921372.1 2136781 D 508767 CDS YP_001921373.1 188589161 6320612 2137067..2137711 1 NC_010723.1 identified by match to protein family HMM PF07853; hypothetical protein 2137711 6320612 CLH_1992 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921373.1 2137067 D 508767 CDS YP_001921374.1 188588152 6318562 2138021..2139253 1 NC_010723.1 identified by match to protein family HMM PF00999; GerN 2139253 6318562 CLH_1993 Clostridium botulinum E3 str. Alaska E43 GerN YP_001921374.1 2138021 D 508767 CDS YP_001921375.1 188587666 6319157 complement(2139280..2139936) 1 NC_010723.1 identified by match to protein family HMM PF00805; pentapeptide repeat-containing protein 2139936 6319157 CLH_1994 Clostridium botulinum E3 str. Alaska E43 pentapeptide repeat-containing protein YP_001921375.1 2139280 R 508767 CDS YP_001921376.1 188588140 6320132 complement(2140020..2140445) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2140445 6320132 CLH_1995 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921376.1 2140020 R 508767 CDS YP_001921377.1 188588840 6319172 complement(2140438..2140806) 1 NC_010723.1 identified by match to protein family HMM PF01909; DNA polymerase, beta domain-containing protein region 2140806 6319172 CLH_1996 Clostridium botulinum E3 str. Alaska E43 DNA polymerase, beta domain-containing protein region YP_001921377.1 2140438 R 508767 CDS YP_001921378.1 188589794 6318259 complement(2141122..2143131) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 2143131 6318259 CLH_1997 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001921378.1 2141122 R 508767 CDS YP_001921379.1 188590416 6320613 complement(2143406..2146036) 1 NC_010723.1 identified by match to protein family HMM PF00171; match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2146036 6320613 CLH_1998 Clostridium botulinum E3 str. Alaska E43 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_001921379.1 2143406 R 508767 CDS YP_001921380.1 188590455 6318558 complement(2146257..2147297) 1 NC_010723.1 hypothetical protein 2147297 6318558 CLH_1999 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921380.1 2146257 R 508767 CDS YP_001921381.1 188588019 6317946 complement(2147302..2147856) 1 NC_010723.1 identified by match to protein family HMM PF04542; match to protein family HMM PF08281; match to protein family HMM TIGR02937; RNA polymerase sigma-70 factor 2147856 6317946 CLH_2000 Clostridium botulinum E3 str. Alaska E43 RNA polymerase sigma-70 factor YP_001921381.1 2147302 R 508767 CDS YP_001921382.1 188588492 6319848 2148147..2149613 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023; polysaccharide biosynthesis protein 2149613 6319848 CLH_2001 Clostridium botulinum E3 str. Alaska E43 polysaccharide biosynthesis protein YP_001921382.1 2148147 D 508767 CDS YP_001921383.1 188589432 6319516 complement(2149765..2151012) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2151012 6319516 CLH_2002 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921383.1 2149765 R 508767 CDS YP_001921384.1 188589012 6318342 complement(2151054..2152331) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2152331 6318342 CLH_2003 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921384.1 2151054 R 508767 CDS YP_001921385.1 188587952 6318225 2152514..2152939 1 NC_010723.1 hypothetical protein 2152939 6318225 CLH_2004 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921385.1 2152514 D 508767 CDS YP_001921386.1 188590770 6317397 2152926..2153369 1 NC_010723.1 hypothetical protein 2153369 6317397 CLH_2005 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921386.1 2152926 D 508767 CDS YP_001921387.1 188589847 6320070 complement(2153485..2154132) 1 NC_010723.1 identified by match to protein family HMM PF02525; FMN-dependent NADH-azoreductase family protein 2154132 6320070 CLH_2006 Clostridium botulinum E3 str. Alaska E43 FMN-dependent NADH-azoreductase family protein YP_001921387.1 2153485 R 508767 CDS YP_001921388.1 188587658 6319458 complement(2154222..2155583) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; subtilin biosynthesis sensor protein SpaK 2155583 6319458 CLH_2007 Clostridium botulinum E3 str. Alaska E43 subtilin biosynthesis sensor protein SpaK YP_001921388.1 2154222 R 508767 CDS YP_001921389.1 188590225 6319897 complement(2155571..2156233) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; subtilin biosynthesis regulatory protein SpaR 2156233 6319897 CLH_2008 Clostridium botulinum E3 str. Alaska E43 subtilin biosynthesis regulatory protein SpaR YP_001921389.1 2155571 R 508767 CDS YP_001921390.1 188589448 6317292 complement(2156261..2157019) 1 NC_010723.1 lantibiotic transport-associated permease SpaG/mutG 2157019 6317292 CLH_2009 Clostridium botulinum E3 str. Alaska E43 lantibiotic transport-associated permease SpaG/mutG YP_001921390.1 2156261 R 508767 CDS YP_001921391.1 188588520 6319171 complement(2157026..2157772) 1 NC_010723.1 lantibiotic permease protein SpaE/mutE 2157772 6319171 CLH_2010 Clostridium botulinum E3 str. Alaska E43 lantibiotic permease protein SpaE/mutE YP_001921391.1 2157026 R 508767 CDS YP_001921392.1 188589831 6320541 complement(2157776..2158480) 1 NC_010723.1 identified by match to protein family HMM PF00005; bacitracin transport ATP-binding protein BcrA 2158480 6320541 CLH_2011 Clostridium botulinum E3 str. Alaska E43 bacitracin transport ATP-binding protein BcrA YP_001921392.1 2157776 R 508767 CDS YP_001921393.1 188588877 6319672 complement(2158569..2159309) 1 NC_010723.1 identified by match to protein family HMM PF01863; hypothetical protein 2159309 6319672 CLH_2012 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921393.1 2158569 R 508767 CDS YP_001921394.1 188587726 6318869 complement(2159391..2159699) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2159699 6318869 CLH_2013 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921394.1 2159391 R 508767 CDS YP_001921395.1 188590079 6319769 complement(2160122..2160292) 1 NC_010723.1 flavodoxin 2160292 6319769 CLH_2014 Clostridium botulinum E3 str. Alaska E43 flavodoxin YP_001921395.1 2160122 R 508767 CDS YP_001921396.1 188589571 6317245 2160691..2160963 1 NC_010723.1 hypothetical protein 2160963 6317245 CLH_2015 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921396.1 2160691 D 508767 CDS YP_001921397.1 188588564 6320279 complement(2161070..2162071) 1 NC_010723.1 identified by match to protein family HMM PF00877; putative surface antigen 2162071 6320279 CLH_2016 Clostridium botulinum E3 str. Alaska E43 putative surface antigen YP_001921397.1 2161070 R 508767 CDS YP_001921398.1 188588922 6318411 complement(2162524..2162898) 1 NC_010723.1 hypothetical protein 2162898 6318411 CLH_2017 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921398.1 2162524 R 508767 CDS YP_001921399.1 188589720 6318098 2163264..2163524 1 NC_010723.1 hypothetical protein 2163524 6318098 CLH_2018 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921399.1 2163264 D 508767 CDS YP_001921400.1 188589055 6318050 2163800..2164195 1 NC_010723.1 thioesterase family protein 2164195 6318050 CLH_2019 Clostridium botulinum E3 str. Alaska E43 thioesterase family protein YP_001921400.1 2163800 D 508767 CDS YP_001921401.1 188589370 6319572 complement(2164425..2165246) 1 NC_010723.1 hypothetical protein 2165246 6319572 CLH_2020 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921401.1 2164425 R 508767 CDS YP_001921402.1 188590071 6320224 complement(2165439..2166440) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2166440 6320224 CLH_2021 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921402.1 2165439 R 508767 CDS YP_001921403.1 188587781 6317796 complement(2166424..2166921) 1 NC_010723.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; RNA polymerase sigma-70 factor 2166921 6317796 CLH_2022 Clostridium botulinum E3 str. Alaska E43 RNA polymerase sigma-70 factor YP_001921403.1 2166424 R 508767 CDS YP_001921404.1 188588094 6318278 complement(2167220..2168311) 1 NC_010723.1 Catalyzes the formation of PRPP from ATP and ribose 5-phosphate; phosphoribosylpyrophosphate synthetase 2168311 6318278 CLH_2023 Clostridium botulinum E3 str. Alaska E43 phosphoribosylpyrophosphate synthetase YP_001921404.1 2167220 R 508767 CDS YP_001921405.1 188588817 6318215 2168713..2169261 1 NC_010723.1 identified by match to protein family HMM PF01386; match to protein family HMM TIGR00731; 50S ribosomal protein L25 2169261 6318215 CLH_2024 Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L25 YP_001921405.1 2168713 D 508767 CDS YP_001921406.1 188589956 6320293 2169501..2170046 1 NC_010723.1 identified by match to protein family HMM PF01386; match to protein family HMM TIGR00731; 50S ribosomal protein L25 2170046 6320293 CLH_2025 Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L25 YP_001921406.1 2169501 D 508767 CDS YP_001921407.1 188590617 6319535 complement(2170340..2172097) 1 NC_010723.1 identified by match to protein family HMM PF00271; ATP-dependent RNA helicase, superfamily II 2172097 6319535 CLH_2026 Clostridium botulinum E3 str. Alaska E43 ATP-dependent RNA helicase, superfamily II YP_001921407.1 2170340 R 508767 CDS YP_001921408.1 188587725 6318795 2172475..2173233 1 NC_010723.1 hypothetical protein 2173233 6318795 CLH_2027 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921408.1 2172475 D 508767 CDS YP_001921409.1 188590314 6319768 complement(2173408..2174187) 1 NC_010723.1 identified by match to protein family HMM PF01487; match to protein family HMM TIGR01093; 3-dehydroquinate dehydratase 2174187 aroD 6319768 aroD Clostridium botulinum E3 str. Alaska E43 3-dehydroquinate dehydratase YP_001921409.1 2173408 R 508767 CDS YP_001921410.1 188588770 6320449 complement(2174237..2174635) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2174635 6320449 CLH_2029 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921410.1 2174237 R 508767 CDS YP_001921411.1 188588051 6319050 complement(2174677..2175897) 1 NC_010723.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 2175897 pepT 6319050 pepT Clostridium botulinum E3 str. Alaska E43 peptidase T YP_001921411.1 2174677 R 508767 CDS YP_001921412.1 188590685 6318938 complement(2176135..2177910) 1 NC_010723.1 identified by match to protein family HMM PF03961; hypothetical protein 2177910 6318938 CLH_2031 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921412.1 2176135 R 508767 CDS YP_001921413.1 188589994 6320327 2178464..2178709 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2178709 6320327 CLH_2032 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921413.1 2178464 D 508767 CDS YP_001921414.1 188588661 6320211 complement(2178872..2180236) 1 NC_010723.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08239; surface protective antigen SpaB 2180236 6320211 CLH_2033 Clostridium botulinum E3 str. Alaska E43 surface protective antigen SpaB YP_001921414.1 2178872 R 508767 CDS YP_001921415.1 188587559 6318078 2180665..2184213 1 NC_010723.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 2184213 6318078 CLH_2034 Clostridium botulinum E3 str. Alaska E43 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_001921415.1 2180665 D 508767 CDS YP_001921416.1 188590266 6319417 2184638..2187784 1 NC_010723.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254; MorA 2187784 6319417 CLH_2035 Clostridium botulinum E3 str. Alaska E43 MorA YP_001921416.1 2184638 D 508767 CDS YP_001921417.1 188589311 6317441 2188001..2188720 1 NC_010723.1 identified by match to protein family HMM PF01171; ExsB family protein 2188720 6317441 CLH_2036 Clostridium botulinum E3 str. Alaska E43 ExsB family protein YP_001921417.1 2188001 D 508767 CDS YP_001921418.1 188588792 6317560 complement(2188799..2189422) 1 NC_010723.1 hypothetical protein 2189422 6317560 CLH_2037 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921418.1 2188799 R 508767 CDS YP_001921419.1 188589863 6319176 2189842..2190450 1 NC_010723.1 hypothetical protein 2190450 6319176 CLH_2038 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921419.1 2189842 D 508767 CDS YP_001921420.1 188587706 6317940 2190482..2191174 1 NC_010723.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 2191174 sfsA 6317940 sfsA Clostridium botulinum E3 str. Alaska E43 sugar fermentation stimulation protein A YP_001921420.1 2190482 D 508767 CDS YP_001921421.1 188588398 6320586 complement(2191327..2191731) 1 NC_010723.1 identified by match to protein family HMM PF01451; arsenate reductase 2191731 6320586 CLH_2040 Clostridium botulinum E3 str. Alaska E43 arsenate reductase YP_001921421.1 2191327 R 508767 CDS YP_001921422.1 188589527 6319930 complement(2191759..2192085) 1 NC_010723.1 identified by match to protein family HMM PF01022; arsenical resistance operon repressor 2192085 6319930 CLH_2041 Clostridium botulinum E3 str. Alaska E43 arsenical resistance operon repressor YP_001921422.1 2191759 R 508767 CDS YP_001921423.1 188590217 6318147 2192723..2193175 1 NC_010723.1 identified by match to protein family HMM PF00583; GnaT-family acetyltransferase 2193175 6318147 CLH_2042 Clostridium botulinum E3 str. Alaska E43 GnaT-family acetyltransferase YP_001921423.1 2192723 D 508767 CDS YP_001921424.1 188588072 6317619 complement(2193205..2193360) 1 NC_010723.1 hypothetical protein 2193360 6317619 CLH_2043 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921424.1 2193205 R 508767 CDS YP_001921425.1 188588992 6319018 complement(2193562..2195454) 1 NC_010723.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427; heat-responsive suppressor HrsA 2195454 6319018 CLH_2044 Clostridium botulinum E3 str. Alaska E43 heat-responsive suppressor HrsA YP_001921425.1 2193562 R 508767 CDS YP_001921426.1 188590080 6319107 complement(2195476..2196378) 1 NC_010723.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase 2196378 pfkB 6319107 pfkB Clostridium botulinum E3 str. Alaska E43 1-phosphofructokinase YP_001921426.1 2195476 R 508767 CDS YP_001921427.1 188590786 6317745 complement(2196371..2197126) 1 NC_010723.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; fructose repressor 2197126 6317745 CLH_2046 Clostridium botulinum E3 str. Alaska E43 fructose repressor YP_001921427.1 2196371 R 508767 CDS YP_001921428.1 188589165 6319066 complement(2197812..2198507) 1 NC_010723.1 identified by match to protein family HMM PF02811; PHP domain-containing protein 2198507 6319066 CLH_2047 Clostridium botulinum E3 str. Alaska E43 PHP domain-containing protein YP_001921428.1 2197812 R 508767 CDS YP_001921429.1 188588198 6320057 complement(2198639..2199997) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 2199997 6320057 CLH_2048 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001921429.1 2198639 R 508767 CDS YP_001921430.1 188589132 6319532 complement(2200215..2200763) 1 NC_010723.1 identified by match to protein family HMM PF00300; putative phosphoglycerate mutase family protein 2200763 6319532 CLH_2049 Clostridium botulinum E3 str. Alaska E43 putative phosphoglycerate mutase family protein YP_001921430.1 2200215 R 508767 CDS YP_001921431.1 188588162 6319961 complement(2201273..2202970) 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512; periplasmic [Fe] hydrogenase 1 2202970 6319961 CLH_2050 Clostridium botulinum E3 str. Alaska E43 periplasmic [Fe] hydrogenase 1 YP_001921431.1 2201273 R 508767 CDS YP_001921432.1 188589360 6319244 complement(2203013..2204893) 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01512; putative iron hydrogenase, electron-transfer subunit 2204893 6319244 CLH_2051 Clostridium botulinum E3 str. Alaska E43 putative iron hydrogenase, electron-transfer subunit YP_001921432.1 2203013 R 508767 CDS YP_001921433.1 188588389 6318096 complement(2204883..2205374) 1 NC_010723.1 identified by match to protein family HMM PF01257; Fe-hydrogenase gamma subunit 2205374 6318096 CLH_2052 Clostridium botulinum E3 str. Alaska E43 Fe-hydrogenase gamma subunit YP_001921433.1 2204883 R 508767 CDS YP_001921434.1 188587940 6319717 complement(2205747..2205899) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2205899 6319717 CLH_2053 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921434.1 2205747 R 508767 CDS YP_001921435.1 188590472 6317570 2206196..2207623 1 NC_010723.1 identified by match to protein family HMM PF00614; cardiolipin synthetase 2207623 6317570 CLH_2054 Clostridium botulinum E3 str. Alaska E43 cardiolipin synthetase YP_001921435.1 2206196 D 508767 CDS YP_001921436.1 188589789 6320439 2207730..2208920 1 NC_010723.1 identified by match to protein family HMM PF01594; hypothetical protein 2208920 6320439 CLH_2055 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921436.1 2207730 D 508767 CDS YP_001921437.1 188589015 6318358 complement(2208988..2210070) 1 NC_010723.1 identified by match to protein family HMM PF00561; lysophospholipase l2 pldb, hydrolase of alpha/beta superfamily 2210070 6318358 CLH_2056 Clostridium botulinum E3 str. Alaska E43 lysophospholipase l2 pldb, hydrolase of alpha/beta superfamily YP_001921437.1 2208988 R 508767 CDS YP_001921438.1 188590213 6319004 complement(2210524..2211072) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2211072 6319004 CLH_2057 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921438.1 2210524 R 508767 CDS YP_001921439.1 188587618 6317572 complement(2211340..2212662) 1 NC_010723.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03222; match to protein family HMM PF03845; amino acid permease 2212662 6317572 CLH_2058 Clostridium botulinum E3 str. Alaska E43 amino acid permease YP_001921439.1 2211340 R 508767 CDS YP_001921440.1 188589698 6320508 complement(2212961..2213422) 1 NC_010723.1 identified by match to protein family HMM PF06496; glutathione-regulated potassium-efflux system protein 2213422 6320508 CLH_2059 Clostridium botulinum E3 str. Alaska E43 glutathione-regulated potassium-efflux system protein YP_001921440.1 2212961 R 508767 CDS YP_001921441.1 188590495 6318576 complement(2213661..2214899) 1 NC_010723.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2214899 6318576 CLH_2060 Clostridium botulinum E3 str. Alaska E43 dihydropyrimidine dehydrogenase YP_001921441.1 2213661 R 508767 CDS YP_001921442.1 188588282 6320174 complement(2214899..2216170) 1 NC_010723.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; oxidoreductase YeiT 2216170 6320174 CLH_2061 Clostridium botulinum E3 str. Alaska E43 oxidoreductase YeiT YP_001921442.1 2214899 R 508767 CDS YP_001921443.1 188588975 6319803 complement(2217260..2218381) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2218381 6319803 CLH_2062 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921443.1 2217260 R 508767 CDS YP_001921444.1 188589295 6319355 complement(2218388..2219050) 1 NC_010723.1 Heat shock-induced; putative RNA polymerase sigma factor SigI 2219050 6319355 CLH_2063 Clostridium botulinum E3 str. Alaska E43 putative RNA polymerase sigma factor SigI YP_001921444.1 2218388 R 508767 CDS YP_001921445.1 188590201 6320521 complement(2219414..2220466) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2220466 6320521 CLH_2064 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921445.1 2219414 R 508767 CDS YP_001921446.1 188590746 6317656 2220653..2221930 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2221930 6317656 CLH_2065 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921446.1 2220653 D 508767 CDS YP_001921447.1 188588369 6318091 2221977..2226230 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2226230 6318091 CLH_2066 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921447.1 2221977 D 508767 CDS YP_001921448.1 188588731 6319524 complement(2226331..2226939) 1 NC_010723.1 putative ribonuclease 2226939 6319524 CLH_2067 Clostridium botulinum E3 str. Alaska E43 putative ribonuclease YP_001921448.1 2226331 R 508767 CDS YP_001921449.1 188587765 6320048 complement(2227211..2228260) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2228260 6320048 CLH_2068 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921449.1 2227211 R 508767 CDS YP_001921450.1 188587761 6319449 complement(2228475..2231627) 1 NC_010723.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; match to protein family HMM PF08455; ATP-dependent helicase 2231627 6319449 CLH_2069 Clostridium botulinum E3 str. Alaska E43 ATP-dependent helicase YP_001921450.1 2228475 R 508767 CDS YP_001921451.1 188590105 6319974 complement(2231834..2232352) 1 NC_010723.1 identified by match to protein family HMM PF00226; match to protein family HMM PF07719; DnaJ family molecular chaperone 2232352 6319974 CLH_2070 Clostridium botulinum E3 str. Alaska E43 DnaJ family molecular chaperone YP_001921451.1 2231834 R 508767 CDS YP_001921452.1 188589125 6317495 complement(2232543..2234981) 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389; ATP-dependent DNA helicase RecQ 2234981 recQ 6317495 recQ Clostridium botulinum E3 str. Alaska E43 ATP-dependent DNA helicase RecQ YP_001921452.1 2232543 R 508767 CDS YP_001921453.1 188588405 6319577 complement(2235380..2236177) 1 NC_010723.1 identified by match to protein family HMM PF01183; lysozyme M1 2236177 6319577 CLH_2072 Clostridium botulinum E3 str. Alaska E43 lysozyme M1 YP_001921453.1 2235380 R 508767 CDS YP_001921454.1 188589660 6319333 complement(2236234..2236500) 1 NC_010723.1 hypothetical protein 2236500 6319333 CLH_2073 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921454.1 2236234 R 508767 CDS YP_001921455.1 188588908 6320111 complement(2236543..2236794) 1 NC_010723.1 phage holin 2236794 6320111 CLH_2074 Clostridium botulinum E3 str. Alaska E43 phage holin YP_001921455.1 2236543 R 508767 CDS YP_001921456.1 188587643 6317850 complement(2237012..2237179) 1 NC_010723.1 hypothetical protein 2237179 6317850 CLH_2075 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921456.1 2237012 R 508767 CDS YP_001921457.1 188590196 6319468 complement(2237503..2238555) 1 NC_010723.1 identified by match to protein family HMM PF00188; hypothetical protein 2238555 6319468 CLH_2076 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921457.1 2237503 R 508767 CDS YP_001921458.1 188588165 6317713 complement(2238940..2242458) 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate:ferredoxin (flavodoxin) oxidoreductase 2242458 nifJ 6317713 nifJ Clostridium botulinum E3 str. Alaska E43 pyruvate:ferredoxin (flavodoxin) oxidoreductase YP_001921458.1 2238940 R 508767 CDS YP_001921459.1 188590119 6319503 2242870..2243277 1 NC_010723.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149; hypothetical protein 2243277 6319503 CLH_2078 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921459.1 2242870 D 508767 CDS YP_001921460.1 188588497 6317267 complement(2243330..2244466) 1 NC_010723.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 2244466 6317267 CLH_2079 Clostridium botulinum E3 str. Alaska E43 glycerate kinase YP_001921460.1 2243330 R 508767 CDS YP_001921461.1 188587587 6317514 complement(2244517..2245773) 1 NC_010723.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; GntP family permease 2245773 6317514 CLH_2080 Clostridium botulinum E3 str. Alaska E43 GntP family permease YP_001921461.1 2244517 R 508767 CDS YP_001921462.1 188588325 6318806 complement(2245939..2247003) 1 NC_010723.1 identified by match to protein family HMM PF05651; sugar diacid utilization regulator 2247003 6318806 CLH_2081 Clostridium botulinum E3 str. Alaska E43 sugar diacid utilization regulator YP_001921462.1 2245939 R 508767 CDS YP_001921463.1 188590494 6319946 complement(2247607..2247762) 1 NC_010723.1 hypothetical protein 2247762 6319946 CLH_2082 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921463.1 2247607 R 508767 CDS YP_001921464.1 188587916 6320173 complement(2247940..2249226) 1 NC_010723.1 putative multidrug efflux pump, outer membrane protein 2249226 6320173 CLH_2083 Clostridium botulinum E3 str. Alaska E43 putative multidrug efflux pump, outer membrane protein YP_001921464.1 2247940 R 508767 CDS YP_001921465.1 188590287 6319424 complement(2249281..2250477) 1 NC_010723.1 putative ABC-2 type transporter 2250477 6319424 CLH_2084 Clostridium botulinum E3 str. Alaska E43 putative ABC-2 type transporter YP_001921465.1 2249281 R 508767 CDS YP_001921466.1 188589176 6318003 complement(2250477..2251730) 1 NC_010723.1 hypothetical protein 2251730 6318003 CLH_2085 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921466.1 2250477 R 508767 CDS YP_001921467.1 188589092 6317814 complement(2251741..2252799) 1 NC_010723.1 identified by match to protein family HMM PF00529; putative secretion protein HlyD family protein 2252799 6317814 CLH_2086 Clostridium botulinum E3 str. Alaska E43 putative secretion protein HlyD family protein YP_001921467.1 2251741 R 508767 CDS YP_001921468.1 188588487 6318168 complement(2252827..2253312) 1 NC_010723.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 2253312 6318168 CLH_2087 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, MarR family YP_001921468.1 2252827 R 508767 CDS YP_001921469.1 188589221 6320152 complement(2253763..2254536) 1 NC_010723.1 identified by match to protein family HMM PF03883; hypothetical protein 2254536 6320152 CLH_2088 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921469.1 2253763 R 508767 CDS YP_001921470.1 188589625 6317351 2254814..2255803 1 NC_010723.1 hypothetical protein 2255803 6317351 CLH_2089 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921470.1 2254814 D 508767 CDS YP_001921471.1 188590534 6318554 2255800..2257077 1 NC_010723.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 2257077 6318554 CLH_2090 Clostridium botulinum E3 str. Alaska E43 pyridine nucleotide-disulfide oxidoreductase family protein YP_001921471.1 2255800 D 508767 CDS YP_001921472.1 188588227 6320246 complement(2257152..2258021) 1 NC_010723.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 2258021 dacB 6320246 dacB Clostridium botulinum E3 str. Alaska E43 D-alanyl-D-alanine carboxypeptidase YP_001921472.1 2257152 R 508767 CDS YP_001921473.1 188589130 6319649 2258177..2258743 1 NC_010723.1 hypothetical protein 2258743 6319649 CLH_2092 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921473.1 2258177 D 508767 CDS YP_001921474.1 188589211 6319959 2258733..2259215 1 NC_010723.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874; sporulation protein YtfJ 2259215 ytfJ 6319959 ytfJ Clostridium botulinum E3 str. Alaska E43 sporulation protein YtfJ YP_001921474.1 2258733 D 508767 CDS YP_001921475.1 188590070 6317650 complement(2259407..2260000) 1 NC_010723.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 2260000 scpB 6317650 scpB Clostridium botulinum E3 str. Alaska E43 segregation and condensation protein B YP_001921475.1 2259407 R 508767 CDS YP_001921476.1 188587714 6317712 complement(2259984..2260739) 1 NC_010723.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 2260739 scpA 6317712 scpA Clostridium botulinum E3 str. Alaska E43 segregation and condensation protein A YP_001921476.1 2259984 R 508767 CDS YP_001921477.1 188588716 6317237 complement(2260969..2262159) 1 NC_010723.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943; penicillin-binding protein DacF 2262159 6317237 CLH_2096 Clostridium botulinum E3 str. Alaska E43 penicillin-binding protein DacF YP_001921477.1 2260969 R 508767 CDS YP_001921478.1 188590721 6317766 complement(2262897..2263979) 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo beta-lactamase family protein 2263979 6317766 CLH_2097 Clostridium botulinum E3 str. Alaska E43 metallo beta-lactamase family protein YP_001921478.1 2262897 R 508767 CDS YP_001921479.1 188589820 6320295 complement(2264191..2264412) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2264412 6320295 CLH_2098 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921479.1 2264191 R 508767 CDS YP_001921480.1 188587690 6319833 complement(2264698..2265576) 1 NC_010723.1 identified by match to protein family HMM PF02086; DNA-methyltransferase 2265576 6319833 CLH_2099 Clostridium botulinum E3 str. Alaska E43 DNA-methyltransferase YP_001921480.1 2264698 R 508767 CDS YP_001921481.1 188590049 6318239 complement(2265638..2267227) 1 NC_010723.1 hypothetical protein 2267227 6318239 CLH_2100 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921481.1 2265638 R 508767 CDS YP_001921482.1 188589070 6317576 complement(2267480..2268154) 1 NC_010723.1 identified by match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase 2268154 6317576 CLH_2101 Clostridium botulinum E3 str. Alaska E43 N-acetylmuramoyl-L-alanine amidase YP_001921482.1 2267480 R 508767 CDS YP_001921483.1 188588157 6319441 complement(2268216..2268632) 1 NC_010723.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593; toxin secretion/phage lysis holin 2268632 6319441 CLH_2102 Clostridium botulinum E3 str. Alaska E43 toxin secretion/phage lysis holin YP_001921483.1 2268216 R 508767 CDS YP_001921484.1 188588121 6318398 complement(2268732..2268956) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2268956 6318398 CLH_2103 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921484.1 2268732 R 508767 CDS YP_001921485.1 188590678 6318876 complement(2269044..2269358) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2269358 6318876 CLH_2104 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921485.1 2269044 R 508767 CDS YP_001921486.1 188589403 6320249 complement(2269372..2270889) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2270889 6320249 CLH_2105 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921486.1 2269372 R 508767 CDS YP_001921487.1 188588681 6318962 complement(2270908..2272653) 1 NC_010723.1 identified by match to protein family HMM TIGR01665; putative phage endopeptidase 2272653 6318962 CLH_2106 Clostridium botulinum E3 str. Alaska E43 putative phage endopeptidase YP_001921487.1 2270908 R 508767 CDS YP_001921488.1 188587609 6318443 complement(2272650..2273324) 1 NC_010723.1 identified by match to protein family HMM TIGR01633; putative phage tail component 2273324 6318443 CLH_2107 Clostridium botulinum E3 str. Alaska E43 putative phage tail component YP_001921488.1 2272650 R 508767 CDS YP_001921489.1 188588506 6319525 complement(2273340..2276810) 1 NC_010723.1 identified by match to protein family HMM PF05017; match to protein family HMM TIGR01760; tail tape measure protein 2276810 6319525 CLH_2108 Clostridium botulinum E3 str. Alaska E43 tail tape measure protein YP_001921489.1 2273340 R 508767 CDS YP_001921490.1 188588963 6318205 complement(2276860..2277123) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2277123 6318205 CLH_2109 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921490.1 2276860 R 508767 CDS YP_001921491.1 188589928 6317521 complement(2277126..2277449) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2277449 6317521 CLH_2110 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921491.1 2277126 R 508767 CDS YP_001921492.1 188590433 6319495 complement(2277452..2278033) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2278033 6319495 CLH_2111 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921492.1 2277452 R 508767 CDS YP_001921493.1 188588002 6320503 complement(2278036..2278356) 1 NC_010723.1 hypothetical protein 2278356 6320503 CLH_2112 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921493.1 2278036 R 508767 CDS YP_001921494.1 188589968 6319241 complement(2278349..2278738) 1 NC_010723.1 hypothetical protein 2278738 6319241 CLH_2113 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921494.1 2278349 R 508767 CDS YP_001921495.1 188587568 6320402 complement(2278738..2279073) 1 NC_010723.1 hypothetical protein 2279073 6320402 CLH_2114 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921495.1 2278738 R 508767 CDS YP_001921496.1 188588105 6317968 complement(2279048..2279377) 1 NC_010723.1 Gp6 protein 2279377 6317968 CLH_2115 Clostridium botulinum E3 str. Alaska E43 Gp6 protein YP_001921496.1 2279048 R 508767 CDS YP_001921497.1 188589066 6317973 complement(2279392..2280588) 1 NC_010723.1 mAjor capsid protein a 2280588 6317973 CLH_2116 Clostridium botulinum E3 str. Alaska E43 mAjor capsid protein a YP_001921497.1 2279392 R 508767 CDS YP_001921498.1 188590464 6319336 complement(2280588..2281379) 1 NC_010723.1 identified by match to protein family HMM PF00574; peptidase S14, ClpP 2281379 6319336 CLH_2117 Clostridium botulinum E3 str. Alaska E43 peptidase S14, ClpP YP_001921498.1 2280588 R 508767 CDS YP_001921499.1 188588312 6320262 complement(2281381..2282529) 1 NC_010723.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 2282529 6320262 CLH_2118 Clostridium botulinum E3 str. Alaska E43 phage portal protein, HK97 family YP_001921499.1 2281381 R 508767 CDS YP_001921500.1 188589030 6319986 complement(2282578..2284233) 1 NC_010723.1 identified by match to protein family HMM PF03354; putative phage terminase, large subunit 2284233 6319986 CLH_2119 Clostridium botulinum E3 str. Alaska E43 putative phage terminase, large subunit YP_001921500.1 2282578 R 508767 CDS YP_001921501.1 188589330 6319753 complement(2284214..2284768) 1 NC_010723.1 hypothetical protein 2284768 6319753 CLH_2120 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921501.1 2284214 R 508767 CDS YP_001921502.1 188588907 6318758 complement(2284871..2285197) 1 NC_010723.1 identified by match to protein family HMM PF01844; Gp54 protein 2285197 6318758 CLH_2121 Clostridium botulinum E3 str. Alaska E43 Gp54 protein YP_001921502.1 2284871 R 508767 CDS YP_001921503.1 188588001 6317849 complement(2285185..2285502) 1 NC_010723.1 hypothetical protein 2285502 6317849 CLH_2122 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921503.1 2285185 R 508767 CDS YP_001921504.1 188590040 6320210 complement(2285656..2286198) 1 NC_010723.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 2286198 6320210 CLH_2123 Clostridium botulinum E3 str. Alaska E43 site-specific recombinase, phage integrase family YP_001921504.1 2285656 R 508767 CDS YP_001921505.1 188589534 6320491 complement(2286195..2286431) 1 NC_010723.1 hypothetical protein 2286431 6320491 CLH_2124 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921505.1 2286195 R 508767 CDS YP_001921506.1 188588243 6319238 complement(2286475..2286615) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2286615 6319238 CLH_2125 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921506.1 2286475 R 508767 CDS YP_001921507.1 188587741 6319582 complement(2286609..2286998) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2286998 6319582 CLH_2126 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921507.1 2286609 R 508767 CDS YP_001921508.1 188589745 6319749 complement(2287923..2288141) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2288141 6319749 CLH_2127 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921508.1 2287923 R 508767 CDS YP_001921509.1 188588830 6320036 complement(2288167..2288352) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2288352 6320036 CLH_2128 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921509.1 2288167 R 508767 CDS YP_001921510.1 188588073 6318145 complement(2288372..2288584) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2288584 6318145 CLH_2129 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921510.1 2288372 R 508767 CDS YP_001921511.1 188590435 6318248 complement(2288715..2288981) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2288981 6318248 CLH_2130 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921511.1 2288715 R 508767 CDS YP_001921512.1 188588708 6320423 complement(2289006..2289161) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2289161 6320423 CLH_2131 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921512.1 2289006 R 508767 CDS YP_001921513.1 188587777 6319201 complement(2289167..2289280) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2289280 6319201 CLH_2132 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921513.1 2289167 R 508767 CDS YP_001921514.1 188587563 6319476 complement(2289342..2290208) 1 NC_010723.1 phage protein 2290208 6319476 CLH_2133 Clostridium botulinum E3 str. Alaska E43 phage protein YP_001921514.1 2289342 R 508767 CDS YP_001921515.1 188590306 6319553 complement(2290324..2291475) 1 NC_010723.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; ParB protein 2291475 6319553 CLH_2134 Clostridium botulinum E3 str. Alaska E43 ParB protein YP_001921515.1 2290324 R 508767 CDS YP_001921516.1 188589869 6318516 complement(2291460..2292215) 1 NC_010723.1 identified by match to protein family HMM PF01656; SpoOJ regulator protein 2292215 soj 6318516 soj Clostridium botulinum E3 str. Alaska E43 SpoOJ regulator protein YP_001921516.1 2291460 R 508767 CDS YP_001921517.1 188588482 6319498 complement(2292306..2292449) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2292449 6319498 CLH_2136 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921517.1 2292306 R 508767 CDS YP_001921518.1 188588802 6317992 complement(2292437..2292685) 1 NC_010723.1 identified by match to protein family HMM TIGR01764; excisionase family DNA binding domain 2292685 6317992 CLH_2137 Clostridium botulinum E3 str. Alaska E43 excisionase family DNA binding domain YP_001921518.1 2292437 R 508767 CDS YP_001921519.1 188588074 6320315 complement(2292698..2293129) 1 NC_010723.1 putative prophage LambdaCh01, transcriptional regulator 2293129 6320315 CLH_2138 Clostridium botulinum E3 str. Alaska E43 putative prophage LambdaCh01, transcriptional regulator YP_001921519.1 2292698 R 508767 CDS YP_001921520.1 188589566 6318249 complement(2293099..2293212) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2293212 6318249 CLH_2139 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921520.1 2293099 R 508767 CDS YP_001921521.1 188590292 6317375 complement(2293266..2293460) 1 NC_010723.1 identified by match to protein family HMM PF01381; hypothetical protein 2293460 6317375 CLH_2140 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921521.1 2293266 R 508767 CDS YP_001921522.1 188588059 6318994 2293596..2293940 1 NC_010723.1 identified by match to protein family HMM PF01381; DNA-binding protein 2293940 6318994 CLH_2141 Clostridium botulinum E3 str. Alaska E43 DNA-binding protein YP_001921522.1 2293596 D 508767 CDS YP_001921523.1 188588842 6318373 complement(2293966..2295045) 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo beta-lactamase family protein 2295045 6318373 CLH_2142 Clostridium botulinum E3 str. Alaska E43 metallo beta-lactamase family protein YP_001921523.1 2293966 R 508767 CDS YP_001921524.1 188589960 6318647 complement(2295201..2295689) 1 NC_010723.1 identified by match to protein family HMM PF01473; cell wall binding domain-containing protein 2295689 6318647 CLH_2143 Clostridium botulinum E3 str. Alaska E43 cell wall binding domain-containing protein YP_001921524.1 2295201 R 508767 CDS YP_001921525.1 188589313 6319031 2296026..2297078 1 NC_010723.1 hypothetical protein 2297078 6319031 CLH_2144 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921525.1 2296026 D 508767 CDS YP_001921526.1 188590002 6317562 2297154..2297486 1 NC_010723.1 identified by match to protein family HMM PF07060; ProFAR isomerase associated superfamily 2297486 6317562 CLH_2145 Clostridium botulinum E3 str. Alaska E43 ProFAR isomerase associated superfamily YP_001921526.1 2297154 D 508767 CDS YP_001921527.1 188587947 6319790 complement(2297513..2298052) 1 NC_010723.1 hypothetical protein 2298052 6319790 CLH_2146 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921527.1 2297513 R 508767 CDS YP_001921528.1 188588643 6317253 complement(2298063..2298440) 1 NC_010723.1 hypothetical protein 2298440 6317253 CLH_2147 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921528.1 2298063 R 508767 CDS YP_001921529.1 188589753 6319053 2298649..2299146 1 NC_010723.1 identified by match to protein family HMM PF06114; hypothetical protein 2299146 6319053 CLH_2148 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921529.1 2298649 D 508767 CDS YP_001921530.1 188588813 6319895 2299251..2300399 1 NC_010723.1 identified by match to protein family HMM PF00589; phage integrase family protein 2300399 6319895 CLH_2149 Clostridium botulinum E3 str. Alaska E43 phage integrase family protein YP_001921530.1 2299251 D 508767 CDS YP_001921531.1 188589919 6320298 complement(2300481..2301359) 1 NC_010723.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; tyrosine recombinase XerD 2301359 6320298 CLH_2150 Clostridium botulinum E3 str. Alaska E43 tyrosine recombinase XerD YP_001921531.1 2300481 R 508767 CDS YP_001921532.1 188590625 6320398 complement(2301480..2302112) 1 NC_010723.1 identified by match to protein family HMM PF01944; match to protein family HMM TIGR02831; stage II sporulation protein M 2302112 spoIIM 6320398 spoIIM Clostridium botulinum E3 str. Alaska E43 stage II sporulation protein M YP_001921532.1 2301480 R 508767 CDS YP_001921533.1 188588680 6318087 complement(2302313..2303884) 1 NC_010723.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2303884 6318087 CLH_2152 Clostridium botulinum E3 str. Alaska E43 alpha-amylase YP_001921533.1 2302313 R 508767 CDS YP_001921534.1 188589175 6318442 complement(2303993..2304415) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2304415 6318442 CLH_2153 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921534.1 2303993 R 508767 CDS YP_001921535.1 188590174 6317813 2304698..2305240 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2305240 6317813 CLH_2154 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921535.1 2304698 D 508767 CDS YP_001921536.1 188588228 6318641 2305617..2306087 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2306087 6318641 CLH_2155 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921536.1 2305617 D 508767 CDS YP_001921537.1 188589141 6319628 complement(2306133..2306681) 1 NC_010723.1 hypothetical protein 2306681 6319628 CLH_2156 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921537.1 2306133 R 508767 CDS YP_001921538.1 188589693 6319166 complement(2306782..2307417) 1 NC_010723.1 hypothetical protein 2307417 6319166 CLH_2157 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921538.1 2306782 R 508767 CDS YP_001921539.1 188587793 6319598 complement(2307605..2307781) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2307781 6319598 CLH_2158 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921539.1 2307605 R 508767 CDS YP_001921540.1 188588166 6320163 2308512..2308859 1 NC_010723.1 hypothetical protein 2308859 6320163 CLH_2159 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921540.1 2308512 D 508767 CDS YP_001921541.1 188590533 6319507 complement(2309147..2309965) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08769; match to protein family HMM TIGR02875; sporulation transcription factor Spo0A 2309965 spo0A 6319507 spo0A Clostridium botulinum E3 str. Alaska E43 sporulation transcription factor Spo0A YP_001921541.1 2309147 R 508767 CDS YP_001921542.1 188589592 6320245 complement(2310352..2311542) 1 NC_010723.1 identified by match to protein family HMM PF00595; match to protein family HMM PF05580; match to protein family HMM TIGR02860; stage IV sporulation protein B 2311542 spoIVB 6320245 spoIVB Clostridium botulinum E3 str. Alaska E43 stage IV sporulation protein B YP_001921542.1 2310352 R 508767 CDS YP_001921543.1 188588555 6319766 complement(2311835..2313523) 1 NC_010723.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; DNA repair protein RecN 2313523 recN 6319766 recN Clostridium botulinum E3 str. Alaska E43 DNA repair protein RecN YP_001921543.1 2311835 R 508767 CDS YP_001921544.1 188590539 6318139 complement(2313550..2314002) 1 NC_010723.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 2314002 argR 6318139 argR Clostridium botulinum E3 str. Alaska E43 arginine repressor YP_001921544.1 2313550 R 508767 CDS YP_001921545.1 188590187 6320180 complement(2313999..2314853) 1 NC_010723.1 identified by match to protein family HMM PF01513; inorganic polyphosphate/ATP-NAD kinase 2314853 6320180 CLH_2164 Clostridium botulinum E3 str. Alaska E43 inorganic polyphosphate/ATP-NAD kinase YP_001921545.1 2313999 R 508767 CDS YP_001921546.1 188589502 6317784 complement(2314871..2315680) 1 NC_010723.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 2315680 6317784 CLH_2165 Clostridium botulinum E3 str. Alaska E43 hemolysin A YP_001921546.1 2314871 R 508767 CDS YP_001921547.1 188588267 6318682 complement(2315697..2317556) 1 NC_010723.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2317556 dxs 6318682 dxs Clostridium botulinum E3 str. Alaska E43 1-deoxy-D-xylulose-5-phosphate synthase YP_001921547.1 2315697 R 508767 CDS YP_001921548.1 188590181 6319835 complement(2317574..2318443) 1 NC_010723.1 identified by match to protein family HMM PF00348; geranyltranstransferase 2318443 6319835 CLH_2167 Clostridium botulinum E3 str. Alaska E43 geranyltranstransferase YP_001921548.1 2317574 R 508767 CDS YP_001921549.1 188589713 6320256 complement(2318430..2318654) 1 NC_010723.1 hypothetical protein 2318654 6320256 CLH_2168 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921549.1 2318430 R 508767 CDS YP_001921550.1 188587903 6320404 complement(2318667..2319866) 1 NC_010723.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2319866 xseA 6320404 xseA Clostridium botulinum E3 str. Alaska E43 exodeoxyribonuclease VII large subunit YP_001921550.1 2318667 R 508767 CDS YP_001921551.1 188587958 6317426 complement(2319856..2320704) 1 NC_010723.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2320704 6317426 CLH_2170 Clostridium botulinum E3 str. Alaska E43 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001921551.1 2319856 R 508767 CDS YP_001921552.1 188590523 6317269 complement(2320727..2321128) 1 NC_010723.1 identified by match to protein family HMM PF01029; match to protein family HMM TIGR01951; transcription antitermination factor NusB 2321128 nusB 6317269 nusB Clostridium botulinum E3 str. Alaska E43 transcription antitermination factor NusB YP_001921552.1 2320727 R 508767 CDS YP_001921553.1 188589822 6317925 complement(2321247..2321627) 1 NC_010723.1 identified by match to protein family HMM PF03780; alkaline shock protein 2321627 6317925 CLH_2172 Clostridium botulinum E3 str. Alaska E43 alkaline shock protein YP_001921553.1 2321247 R 508767 CDS YP_001921554.1 188589082 6318479 complement(2321744..2322289) 1 NC_010723.1 stage III sporulation protein AH 2322289 6318479 CLH_2173 Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein AH YP_001921554.1 2321744 R 508767 CDS YP_001921555.1 188587937 6318779 complement(2322330..2322959) 1 NC_010723.1 identified by match to protein family HMM TIGR02830; stage III sporulation protein AG 2322959 spoIIIAG 6318779 spoIIIAG Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein AG YP_001921555.1 2322330 R 508767 CDS YP_001921556.1 188590097 6317751 complement(2322971..2323558) 1 NC_010723.1 identified by match to protein family HMM PF09581; match to protein family HMM TIGR02896; stage III sporulation protein af, spoiiiaf 2323558 6317751 CLH_2175 Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein af, spoiiiaf YP_001921556.1 2322971 R 508767 CDS YP_001921557.1 188590581 6317324 complement(2323562..2324818) 1 NC_010723.1 identified by match to protein family HMM PF09546; match to protein family HMM TIGR02829; stage III sporulation protein AE 2324818 spoIIIAE 6317324 spoIIIAE Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein AE YP_001921557.1 2323562 R 508767 CDS YP_001921558.1 188588658 6318113 complement(2324830..2325213) 1 NC_010723.1 identified by match to protein family HMM PF09555; match to protein family HMM TIGR02849; stage III sporulation protein AD 2325213 spoIIIAD 6318113 spoIIIAD Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein AD YP_001921558.1 2324830 R 508767 CDS YP_001921559.1 188589004 6317732 complement(2325222..2325419) 1 NC_010723.1 identified by match to protein family HMM PF06686; match to protein family HMM TIGR02848; stage III sporulation protein AC 2325419 spoIIIAC 6317732 spoIIIAC Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein AC YP_001921559.1 2325222 R 508767 CDS YP_001921560.1 188589722 6318227 complement(2325434..2325952) 1 NC_010723.1 necessary for complete engulfment of forespore; stage III sporulation protein SpoAB 2325952 spoIIIAB 6318227 spoIIIAB Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein SpoAB YP_001921560.1 2325434 R 508767 CDS YP_001921561.1 188590784 6318052 complement(2325940..2326860) 1 NC_010723.1 identified by match to protein family HMM TIGR02858; stage III sporulation protein AA 2326860 spoIIIAA 6318052 spoIIIAA Clostridium botulinum E3 str. Alaska E43 stage III sporulation protein AA YP_001921561.1 2325940 R 508767 CDS YP_001921562.1 188588240 6319064 complement(2327024..2327389) 1 NC_010723.1 hypothetical protein 2327389 6319064 CLH_2181 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921562.1 2327024 R 508767 CDS YP_001921563.1 188589433 6319604 complement(2327476..2328033) 1 NC_010723.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 2328033 efp 6319604 efp Clostridium botulinum E3 str. Alaska E43 elongation factor P YP_001921563.1 2327476 R 508767 CDS YP_001921564.1 188587553 6318343 complement(2328224..2328604) 1 NC_010723.1 putative lipoprotein 2328604 6318343 CLH_2183 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921564.1 2328224 R 508767 CDS YP_001921565.1 188588442 6317931 complement(2328591..2329019) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2329019 6317931 CLH_2184 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921565.1 2328591 R 508767 CDS YP_001921566.1 188589351 6319475 complement(2328970..2329671) 1 NC_010723.1 hypothetical protein 2329671 6319475 CLH_2185 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921566.1 2328970 R 508767 CDS YP_001921567.1 188590757 6318697 complement(2329769..2330161) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2330161 6318697 CLH_2186 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921567.1 2329769 R 508767 CDS YP_001921568.1 188590717 6319118 complement(2330152..2330436) 1 NC_010723.1 hypothetical protein 2330436 6319118 CLH_2187 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921568.1 2330152 R 508767 CDS YP_001921569.1 188587982 6320199 complement(2330618..2331046) 1 NC_010723.1 hypothetical protein 2331046 6320199 CLH_2188 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921569.1 2330618 R 508767 CDS YP_001921570.1 188588050 6319091 complement(2331077..2331514) 1 NC_010723.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; prepilin-type N- cleavage/methylation domain-containing protein 2331514 6319091 CLH_2189 Clostridium botulinum E3 str. Alaska E43 prepilin-type N- cleavage/methylation domain-containing protein YP_001921570.1 2331077 R 508767 CDS YP_001921571.1 188590236 6318937 complement(2331511..2332587) 1 NC_010723.1 identified by match to protein family HMM PF00482; type II secretion system protein F domain 2332587 6318937 CLH_2190 Clostridium botulinum E3 str. Alaska E43 type II secretion system protein F domain YP_001921571.1 2331511 R 508767 CDS YP_001921572.1 188589966 6319028 complement(2332574..2333815) 1 NC_010723.1 identified by match to protein family HMM PF00437; general secretion pathway protein 2333815 6319028 CLH_2191 Clostridium botulinum E3 str. Alaska E43 general secretion pathway protein YP_001921572.1 2332574 R 508767 CDS YP_001921573.1 188588797 6320400 complement(2334045..2335049) 1 NC_010723.1 putative lipoprotein 2335049 6320400 CLH_2192 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921573.1 2334045 R 508767 CDS YP_001921574.1 188589635 6318739 complement(2335076..2335897) 1 NC_010723.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 2335897 dapF 6318739 dapF Clostridium botulinum E3 str. Alaska E43 diaminopimelate epimerase YP_001921574.1 2335076 R 508767 CDS YP_001921575.1 188589096 6318475 2336160..2337893 1 NC_010723.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833; fibronectin-binding protein 2337893 6318475 CLH_2194 Clostridium botulinum E3 str. Alaska E43 fibronectin-binding protein YP_001921575.1 2336160 D 508767 CDS YP_001921576.1 188588187 6319191 complement(2338353..2339513) 1 NC_010723.1 identified by match to protein family HMM PF01170; methyltransferase 2339513 6319191 CLH_2195 Clostridium botulinum E3 str. Alaska E43 methyltransferase YP_001921576.1 2338353 R 508767 CDS YP_001921577.1 188587646 6320053 complement(2339547..2340089) 1 NC_010723.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 2340089 6320053 CLH_2196 Clostridium botulinum E3 str. Alaska E43 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_001921577.1 2339547 R 508767 CDS YP_001921578.1 188590369 6319607 complement(2340116..2341024) 1 NC_010723.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D 2341024 6319607 CLH_2197 Clostridium botulinum E3 str. Alaska E43 ribosomal large subunit pseudouridine synthase D YP_001921578.1 2340116 R 508767 CDS YP_001921579.1 188589276 6318223 complement(2341301..2341921) 1 NC_010723.1 identified by match to protein family HMM PF05103; match to protein family HMM TIGR03544; minicell-associated protein 2341921 6318223 CLH_2198 Clostridium botulinum E3 str. Alaska E43 minicell-associated protein YP_001921579.1 2341301 R 508767 CDS YP_001921580.1 188588620 6317447 complement(2341935..2342699) 1 NC_010723.1 identified by match to protein family HMM PF01479; S4 domain-containing protein 2342699 6317447 CLH_2199 Clostridium botulinum E3 str. Alaska E43 S4 domain-containing protein YP_001921580.1 2341935 R 508767 CDS YP_001921581.1 188587912 6317717 complement(2342702..2342968) 1 NC_010723.1 identified by match to protein family HMM PF02325; yggt family protein 2342968 6317717 CLH_2200 Clostridium botulinum E3 str. Alaska E43 yggt family protein YP_001921581.1 2342702 R 508767 CDS YP_001921582.1 188590065 6318263 complement(2342977..2343438) 1 NC_010723.1 identified by match to protein family HMM PF04472; hypothetical protein 2343438 6318263 CLH_2201 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921582.1 2342977 R 508767 CDS YP_001921583.1 188588531 6320364 complement(2343438..2344112) 1 NC_010723.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044; pyridoxal phosphate enzyme, YggS family 2344112 6320364 CLH_2202 Clostridium botulinum E3 str. Alaska E43 pyridoxal phosphate enzyme, YggS family YP_001921583.1 2343438 R 508767 CDS YP_001921584.1 188588513 6318374 complement(2344215..2344946) 1 NC_010723.1 identified by match to protein family HMM PF05949; hypothetical protein 2344946 6318374 CLH_2203 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921584.1 2344215 R 508767 CDS YP_001921585.1 188587628 6318621 complement(2344960..2345298) 1 NC_010723.1 identified by match to protein family HMM PF06947; small basic protein 2345298 6318621 CLH_2204 Clostridium botulinum E3 str. Alaska E43 small basic protein YP_001921585.1 2344960 R 508767 CDS YP_001921586.1 188590392 6319361 complement(2345319..2346047) 1 NC_010723.1 identified by match to protein family HMM PF05949; division initiation protein 2346047 6319361 CLH_2205 Clostridium botulinum E3 str. Alaska E43 division initiation protein YP_001921586.1 2345319 R 508767 CDS YP_001921587.1 188588894 6317547 complement(2346063..2346728) 1 NC_010723.1 identified by match to protein family HMM PF08478; cell division protein FtsQ 2346728 6317547 CLH_2206 Clostridium botulinum E3 str. Alaska E43 cell division protein FtsQ YP_001921587.1 2346063 R 508767 CDS YP_001921588.1 188590727 6318421 complement(2347120..2348244) 1 NC_010723.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; match to protein family HMM TIGR02615; cell division protein FtsW 2348244 ftsW 6318421 ftsW Clostridium botulinum E3 str. Alaska E43 cell division protein FtsW YP_001921588.1 2347120 R 508767 CDS YP_001921589.1 188589879 6318800 complement(2348386..2349360) 1 NC_010723.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2349360 mraY 6318800 mraY Clostridium botulinum E3 str. Alaska E43 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001921589.1 2348386 R 508767 CDS YP_001921590.1 188588851 6319307 complement(2349401..2350762) 1 NC_010723.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 2350762 6319307 CLH_2209 Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_001921590.1 2349401 R 508767 CDS YP_001921591.1 188589397 6319197 complement(2350782..2352236) 1 NC_010723.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 2352236 murE 6319197 murE Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001921591.1 2350782 R 508767 CDS YP_001921592.1 188590061 6318664 complement(2352361..2354619) 1 NC_010723.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; match to protein family HMM TIGR02214; stage V sporulation protein D 2354619 6318664 CLH_2211 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein D YP_001921592.1 2352361 R 508767 CDS YP_001921593.1 188587897 6320431 complement(2354773..2355276) 1 NC_010723.1 putative cell division protein FtsL 2355276 6320431 CLH_2212 Clostridium botulinum E3 str. Alaska E43 putative cell division protein FtsL YP_001921593.1 2354773 R 508767 CDS YP_001921594.1 188587754 6318038 complement(2355324..2356256) 1 NC_010723.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 2356256 mraW 6318038 mraW Clostridium botulinum E3 str. Alaska E43 S-adenosyl-methyltransferase MraW YP_001921594.1 2355324 R 508767 CDS YP_001921595.1 188588710 6319088 complement(2356269..2356697) 1 NC_010723.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 2356697 mraZ 6319088 mraZ Clostridium botulinum E3 str. Alaska E43 cell division protein MraZ YP_001921595.1 2356269 R 508767 CDS YP_001921596.1 188590777 6318133 complement(2356867..2357148) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2357148 6318133 CLH_2215 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921596.1 2356867 R 508767 CDS YP_001921597.1 188588258 6317952 2357344..2358090 1 NC_010723.1 identified by match to protein family HMM PF03591; AzlC family protein 2358090 6317952 CLH_2216 Clostridium botulinum E3 str. Alaska E43 AzlC family protein YP_001921597.1 2357344 D 508767 CDS YP_001921598.1 188589584 6319882 2358091..2358390 1 NC_010723.1 identified by match to protein family HMM PF05437; branched-chain amino acid transport 2358390 6319882 CLH_2217 Clostridium botulinum E3 str. Alaska E43 branched-chain amino acid transport YP_001921598.1 2358091 D 508767 CDS YP_001921599.1 188590206 6319407 complement(2358570..2358698) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2358698 6319407 CLH_2218 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921599.1 2358570 R 508767 CDS YP_001921600.1 188588211 6317490 complement(2358670..2359506) 1 NC_010723.1 identified by match to protein family HMM PF03741; integral membrane protein TerC 2359506 6317490 CLH_2219 Clostridium botulinum E3 str. Alaska E43 integral membrane protein TerC YP_001921600.1 2358670 R 508767 CDS YP_001921601.1 188590381 6319685 complement(2359658..2360755) 1 NC_010723.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2360755 6319685 CLH_2220 Clostridium botulinum E3 str. Alaska E43 GTP-dependent nucleic acid-binding protein EngD YP_001921601.1 2359658 R 508767 CDS YP_001921602.1 188589638 6320362 2361175..2362044 1 NC_010723.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02884; delta-lactam-biosynthetic de-N-acetylase 2362044 pdaA 6320362 pdaA Clostridium botulinum E3 str. Alaska E43 delta-lactam-biosynthetic de-N-acetylase YP_001921602.1 2361175 D 508767 CDS YP_001921603.1 188589126 6320099 complement(2362402..2363052) 1 NC_010723.1 identified by match to protein family HMM PF04961; methenyltetrahydrofolate cyclohydrolase 2363052 6320099 CLH_2222 Clostridium botulinum E3 str. Alaska E43 methenyltetrahydrofolate cyclohydrolase YP_001921603.1 2362402 R 508767 CDS YP_001921604.1 188588418 6319578 complement(2363065..2363997) 1 NC_010723.1 identified by match to protein family HMM PF04932; O-antigen polymerase family 2363997 6319578 CLH_2223 Clostridium botulinum E3 str. Alaska E43 O-antigen polymerase family YP_001921604.1 2363065 R 508767 CDS YP_001921605.1 188590608 6319757 complement(2364284..2365447) 1 NC_010723.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase 2365447 6319757 CLH_2224 Clostridium botulinum E3 str. Alaska E43 group 1 glycosyl transferase YP_001921605.1 2364284 R 508767 CDS YP_001921606.1 188589908 6319299 complement(2365453..2366736) 1 NC_010723.1 hypothetical protein 2366736 6319299 CLH_2225 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921606.1 2365453 R 508767 CDS YP_001921607.1 188589480 6320535 complement(2366748..2368280) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM PF03023; match to protein family HMM TIGR01695; integral membrane protein MviN 2368280 mviN 6320535 mviN Clostridium botulinum E3 str. Alaska E43 integral membrane protein MviN YP_001921607.1 2366748 R 508767 CDS YP_001921608.1 188588916 6318583 complement(2368286..2368999) 1 NC_010723.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; putative N-acetylmannosaminyltransferase 2368999 6318583 CLH_2227 Clostridium botulinum E3 str. Alaska E43 putative N-acetylmannosaminyltransferase YP_001921608.1 2368286 R 508767 CDS YP_001921609.1 188587541 6319325 complement(2369358..2370446) 1 NC_010723.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; TPR domain-containing protein 2370446 6319325 CLH_2228 Clostridium botulinum E3 str. Alaska E43 TPR domain-containing protein YP_001921609.1 2369358 R 508767 CDS YP_001921610.1 188588947 6318650 complement(2370545..2372272) 1 NC_010723.1 identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 2372272 6318650 CLH_2229 Clostridium botulinum E3 str. Alaska E43 phosphomannomutase YP_001921610.1 2370545 R 508767 CDS YP_001921611.1 188589324 6318915 complement(2372436..2373170) 1 NC_010723.1 identified by match to protein family HMM PF04463; purine nucleoside phosphorylase 2373170 6318915 CLH_2230 Clostridium botulinum E3 str. Alaska E43 purine nucleoside phosphorylase YP_001921611.1 2372436 R 508767 CDS YP_001921612.1 188590038 6317335 complement(2373298..2375655) 1 NC_010723.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 2375655 6317335 CLH_2231 Clostridium botulinum E3 str. Alaska E43 recombination and DNA strand exchange inhibitor protein YP_001921612.1 2373298 R 508767 CDS YP_001921613.1 188588561 6319411 complement(2375669..2378014) 1 NC_010723.1 identified by match to protein family HMM PF01136; peptidase, U32 family 2378014 6319411 CLH_2232 Clostridium botulinum E3 str. Alaska E43 peptidase, U32 family YP_001921613.1 2375669 R 508767 CDS YP_001921614.1 188588032 6319565 complement(2378169..2379776) 1 NC_010723.1 identified by match to protein family HMM PF05164; hypothetical protein 2379776 6319565 CLH_2233 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921614.1 2378169 R 508767 CDS YP_001921615.1 188590024 6318246 complement(2380089..2380235) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2380235 6318246 CLH_2234 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921615.1 2380089 R 508767 CDS YP_001921616.1 188589524 6320000 2380535..2381785 1 NC_010723.1 identified by match to protein family HMM PF07690; major facilitator superfamily permease 2381785 6320000 CLH_2235 Clostridium botulinum E3 str. Alaska E43 major facilitator superfamily permease YP_001921616.1 2380535 D 508767 CDS YP_001921617.1 188588186 6320286 complement(2382075..2382635) 1 NC_010723.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2382635 6320286 CLH_2236 Clostridium botulinum E3 str. Alaska E43 diguanylate cyclase YP_001921617.1 2382075 R 508767 CDS YP_001921618.1 188587686 6319322 complement(2383357..2385057) 1 NC_010723.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM TIGR00254; response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor 2385057 6319322 CLH_2237 Clostridium botulinum E3 str. Alaska E43 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor YP_001921618.1 2383357 R 508767 CDS YP_001921619.1 188589684 6318275 complement(2385410..2386357) 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 2386357 6318275 CLH_2238 Clostridium botulinum E3 str. Alaska E43 metallo-beta-lactamase family protein YP_001921619.1 2385410 R 508767 CDS YP_001921620.1 188590231 6319988 complement(2386721..2387536) 1 NC_010723.1 identified by match to protein family HMM PF00924; mechanosensitive ion channel family protein 2387536 6319988 CLH_2239 Clostridium botulinum E3 str. Alaska E43 mechanosensitive ion channel family protein YP_001921620.1 2386721 R 508767 CDS YP_001921621.1 188587654 6318256 complement(2387644..2388561) 1 NC_010723.1 identified by match to protein family HMM PF02016; muramoyltetrapeptide carboxypeptidase 2388561 6318256 CLH_2240 Clostridium botulinum E3 str. Alaska E43 muramoyltetrapeptide carboxypeptidase YP_001921621.1 2387644 R 508767 CDS YP_001921622.1 188588255 6319610 complement(2388804..2391179) 1 NC_010723.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2391179 pheT 6319610 pheT Clostridium botulinum E3 str. Alaska E43 phenylalanyl-tRNA synthetase subunit beta YP_001921622.1 2388804 R 508767 CDS YP_001921623.1 188589900 6319885 complement(2391299..2392318) 1 NC_010723.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2392318 pheS 6319885 pheS Clostridium botulinum E3 str. Alaska E43 phenylalanyl-tRNA synthetase subunit alpha YP_001921623.1 2391299 R 508767 CDS YP_001921624.1 188590604 6319520 complement(2392846..2394987) 1 NC_010723.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 2394987 hppA 6319520 hppA Clostridium botulinum E3 str. Alaska E43 membrane-bound proton-translocating pyrophosphatase YP_001921624.1 2392846 R 508767 CDS YP_001921625.1 188588020 6319315 complement(2395223..2396011) 1 NC_010723.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; RNA methyltransferase, TrmH family 2396011 6319315 CLH_2244 Clostridium botulinum E3 str. Alaska E43 RNA methyltransferase, TrmH family YP_001921625.1 2395223 R 508767 CDS YP_001921626.1 188588766 6319849 complement(2396026..2396694) 1 NC_010723.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254; potassium uptake protein 2396694 6319849 CLH_2245 Clostridium botulinum E3 str. Alaska E43 potassium uptake protein YP_001921626.1 2396026 R 508767 CDS YP_001921627.1 188588483 6318393 complement(2396708..2398057) 1 NC_010723.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933; TrkH family potassium uptake protein 2398057 6318393 CLH_2246 Clostridium botulinum E3 str. Alaska E43 TrkH family potassium uptake protein YP_001921627.1 2396708 R 508767 CDS YP_001921628.1 188589172 6317993 complement(2398199..2398558) 1 NC_010723.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2398558 rplT 6317993 rplT Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L20 YP_001921628.1 2398199 R 508767 CDS YP_001921629.1 188589898 6318045 complement(2398587..2398784) 1 NC_010723.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 2398784 rpmI 6318045 rpmI Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L35 YP_001921629.1 2398587 R 508767 CDS YP_001921630.1 188587762 6319518 complement(2398806..2399327) 1 NC_010723.1 identified by match to protein family HMM PF00707; match to protein family HMM PF05198; match to protein family HMM TIGR00168; translation initiation factor IF-3 2399327 infC 6319518 infC Clostridium botulinum E3 str. Alaska E43 translation initiation factor IF-3 YP_001921630.1 2398806 R 508767 CDS YP_001921631.1 188588630 6319569 complement(2399484..2400392) 1 NC_010723.1 identified by match to protein family HMM PF08812; match to protein family HMM TIGR02834; putative sporulation protein YtxC 2400392 6319569 CLH_2250 Clostridium botulinum E3 str. Alaska E43 putative sporulation protein YtxC YP_001921631.1 2399484 R 508767 CDS YP_001921632.1 188590440 6320587 2400545..2401249 1 NC_010723.1 hypothetical protein 2401249 6320587 CLH_2251 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921632.1 2400545 D 508767 CDS YP_001921633.1 188590427 6318910 complement(2401520..2402407) 1 NC_010723.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2402407 hslO 6318910 hslO Clostridium botulinum E3 str. Alaska E43 Hsp33-like chaperonin YP_001921633.1 2401520 R 508767 CDS YP_001921634.1 188588259 6320525 complement(2402425..2403162) 1 NC_010723.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; S-adenosylmethionine-dependent methyltransferase 2403162 6320525 CLH_2253 Clostridium botulinum E3 str. Alaska E43 S-adenosylmethionine-dependent methyltransferase YP_001921634.1 2402425 R 508767 CDS YP_001921635.1 188589024 6319883 complement(2403447..2403716) 1 NC_010723.1 small, acid-soluble spore protein, alpha/beta family 2403716 6319883 CLH_2254 Clostridium botulinum E3 str. Alaska E43 small, acid-soluble spore protein, alpha/beta family YP_001921635.1 2403447 R 508767 CDS YP_001921636.1 188589371 6319075 2403990..2404982 1 NC_010723.1 identified by match to protein family HMM PF01118; match to protein family HMM PF02774; match to protein family HMM TIGR01296; aspartate-semialdehyde dehydrogenase 2404982 asd 6319075 asd Clostridium botulinum E3 str. Alaska E43 aspartate-semialdehyde dehydrogenase YP_001921636.1 2403990 D 508767 CDS YP_001921637.1 188589307 6320225 2404999..2405877 1 NC_010723.1 identified by match to protein family HMM PF00701; match to protein family HMM TIGR00674; dihydrodipicolinate synthase 2405877 dapA 6320225 dapA Clostridium botulinum E3 str. Alaska E43 dihydrodipicolinate synthase YP_001921637.1 2404999 D 508767 CDS YP_001921638.1 188590033 6317512 2405887..2406645 1 NC_010723.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 2406645 dapB 6317512 dapB Clostridium botulinum E3 str. Alaska E43 dihydrodipicolinate reductase YP_001921638.1 2405887 D 508767 CDS YP_001921639.1 188588870 6317910 complement(2406710..2408359) 1 NC_010723.1 identified by match to protein family HMM PF00496; oligopeptide-binding protein OppA 2408359 6317910 CLH_2258 Clostridium botulinum E3 str. Alaska E43 oligopeptide-binding protein OppA YP_001921639.1 2406710 R 508767 CDS YP_001921640.1 188590353 6318449 complement(2408551..2409531) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide transport ATP-binding protein AppF 2409531 6318449 CLH_2259 Clostridium botulinum E3 str. Alaska E43 oligopeptide transport ATP-binding protein AppF YP_001921640.1 2408551 R 508767 CDS YP_001921641.1 188587631 6320481 complement(2409531..2410541) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide transport ATP-binding protein OppD 2410541 6320481 CLH_2260 Clostridium botulinum E3 str. Alaska E43 oligopeptide transport ATP-binding protein OppD YP_001921641.1 2409531 R 508767 CDS YP_001921642.1 188588516 6319587 complement(2410554..2411498) 1 NC_010723.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease OppC 2411498 6319587 CLH_2261 Clostridium botulinum E3 str. Alaska E43 oligopeptide transport system permease OppC YP_001921642.1 2410554 R 508767 CDS YP_001921643.1 188589204 6318754 complement(2411517..2412443) 1 NC_010723.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease OppB 2412443 6318754 CLH_2262 Clostridium botulinum E3 str. Alaska E43 oligopeptide transport system permease OppB YP_001921643.1 2411517 R 508767 CDS YP_001921644.1 188588181 6317681 complement(2412988..2414658) 1 NC_010723.1 identified by match to protein family HMM PF00496; oligopeptide ABC transporter periplasmic oligopeptide-binding protein 2414658 oppA 6317681 oppA Clostridium botulinum E3 str. Alaska E43 oligopeptide ABC transporter periplasmic oligopeptide-binding protein YP_001921644.1 2412988 R 508767 CDS YP_001921645.1 188588404 6319359 complement(2415176..2416315) 1 NC_010723.1 identified by match to protein family HMM PF00155; putative aminotransferase A 2416315 6319359 CLH_2264 Clostridium botulinum E3 str. Alaska E43 putative aminotransferase A YP_001921645.1 2415176 R 508767 CDS YP_001921646.1 188589611 6319332 2416537..2417247 1 NC_010723.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503; match to protein family HMM TIGR03532; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 2417247 dapD 6319332 dapD Clostridium botulinum E3 str. Alaska E43 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001921646.1 2416537 D 508767 CDS YP_001921647.1 188590672 6319159 complement(2417385..2418035) 1 NC_010723.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 2418035 6319159 CLH_2266 Clostridium botulinum E3 str. Alaska E43 single-stranded DNA-binding protein YP_001921647.1 2417385 R 508767 CDS YP_001921648.1 188590239 6317904 complement(2418134..2418895) 1 NC_010723.1 identified by match to protein family HMM PF01522; chitooligosaccharide deacetylase 2418895 6317904 CLH_2267 Clostridium botulinum E3 str. Alaska E43 chitooligosaccharide deacetylase YP_001921648.1 2418134 R 508767 CDS YP_001921649.1 188590135 6318963 2419023..2419556 1 NC_010723.1 hypothetical protein 2419556 6318963 CLH_2269 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921649.1 2419023 D 508767 CDS YP_001921650.1 188589057 6317737 complement(2419540..2420433) 1 NC_010723.1 hypothetical protein 2420433 6317737 CLH_2268 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921650.1 2419540 R 508767 CDS YP_001921651.1 188587606 6319345 2420599..2420847 1 NC_010723.1 hypothetical protein 2420847 6319345 CLH_2270 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921651.1 2420599 D 508767 CDS YP_001921652.1 188589613 6319855 complement(2420889..2422859) 1 NC_010723.1 identified by match to protein family HMM PF08797; hiran domain family 2422859 6319855 CLH_2271 Clostridium botulinum E3 str. Alaska E43 hiran domain family YP_001921652.1 2420889 R 508767 CDS YP_001921653.1 188589067 6317884 complement(2422906..2424219) 1 NC_010723.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; folylpolyglutamate synthase 2424219 6317884 CLH_2272 Clostridium botulinum E3 str. Alaska E43 folylpolyglutamate synthase YP_001921653.1 2422906 R 508767 CDS YP_001921654.1 188588743 6319337 complement(2424341..2424661) 1 NC_010723.1 identified by match to protein family HMM PF01906; hypothetical protein 2424661 6319337 CLH_2273 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921654.1 2424341 R 508767 CDS YP_001921655.1 188587843 6317396 complement(2425176..2427818) 1 NC_010723.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 2427818 valS 6317396 valS Clostridium botulinum E3 str. Alaska E43 valyl-tRNA synthetase YP_001921655.1 2425176 R 508767 CDS YP_001921656.1 188589180 6317290 complement(2428373..2429233) 1 NC_010723.1 identified by match to protein family HMM PF02016; LD-carboxypeptidase family protein 2429233 6317290 CLH_2275 Clostridium botulinum E3 str. Alaska E43 LD-carboxypeptidase family protein YP_001921656.1 2428373 R 508767 CDS YP_001921657.1 188588685 6317701 2429773..2430744 1 NC_010723.1 identified by match to protein family HMM PF00535; bactoprenol glucosyl transferase 2430744 6317701 CLH_2276 Clostridium botulinum E3 str. Alaska E43 bactoprenol glucosyl transferase YP_001921657.1 2429773 D 508767 CDS YP_001921658.1 188588327 6319193 2430754..2431158 1 NC_010723.1 identified by match to protein family HMM PF04138; hypothetical protein 2431158 6319193 CLH_2277 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921658.1 2430754 D 508767 CDS YP_001921659.1 188588174 6319918 complement(2431356..2432519) 1 NC_010723.1 identified by match to protein family HMM PF00465; NADH-dependent butanol dehydrogenase a 2432519 6319918 CLH_2278 Clostridium botulinum E3 str. Alaska E43 NADH-dependent butanol dehydrogenase a YP_001921659.1 2431356 R 508767 CDS YP_001921660.1 188590522 6319453 complement(2432750..2433430) 1 NC_010723.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase F 2433430 6319453 CLH_2279 Clostridium botulinum E3 str. Alaska E43 ribosomal large subunit pseudouridine synthase F YP_001921660.1 2432750 R 508767 CDS YP_001921661.1 188589648 6317960 complement(2433524..2436721) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF07494; match to protein family HMM PF07495; sensor histidine kinase/response regulator 2436721 6317960 CLH_2280 Clostridium botulinum E3 str. Alaska E43 sensor histidine kinase/response regulator YP_001921661.1 2433524 R 508767 CDS YP_001921662.1 188588723 6320032 complement(2437027..2437989) 1 NC_010723.1 identified by match to protein family HMM PF03851; match to protein family HMM TIGR00629; putative UV damage endonuclease 2437989 uvsE 6320032 uvsE Clostridium botulinum E3 str. Alaska E43 putative UV damage endonuclease YP_001921662.1 2437027 R 508767 CDS YP_001921663.1 188587773 6320566 complement(2438222..2439106) 1 NC_010723.1 identified by match to protein family HMM TIGR01451; hypothetical protein 2439106 6320566 CLH_2282 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921663.1 2438222 R 508767 CDS YP_001921664.1 188590100 6319995 complement(2439136..2439615) 1 NC_010723.1 hypothetical protein 2439615 6319995 CLH_2283 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921664.1 2439136 R 508767 CDS YP_001921665.1 188589085 6317355 complement(2439767..2447866) 1 NC_010723.1 identified by match to protein family HMM PF01345; match to protein family HMM TIGR01451; hypothetical protein 2447866 6317355 CLH_2284 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921665.1 2439767 R 508767 CDS YP_001921666.1 188588194 6320416 2448090..2451509 1 NC_010723.1 identified by match to protein family HMM TIGR01451; hypothetical protein 2451509 6320416 CLH_2285 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921666.1 2448090 D 508767 CDS YP_001921667.1 188590444 6318072 complement(2451752..2452363) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2452363 6318072 CLH_2286 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921667.1 2451752 R 508767 CDS YP_001921668.1 188589567 6318433 complement(2452516..2453877) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 2453877 6318433 CLH_2287 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001921668.1 2452516 R 508767 CDS YP_001921669.1 188589326 6317376 2454050..2454502 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2454502 6317376 CLH_2288 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921669.1 2454050 D 508767 CDS YP_001921670.1 188588514 6318878 complement(2454715..2454849) 1 NC_010723.1 hypothetical protein 2454849 6318878 CLH_2289 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921670.1 2454715 R 508767 CDS YP_001921671.1 188587877 6318622 complement(2454900..2455046) 1 NC_010723.1 hypothetical protein 2455046 6318622 CLH_2290 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921671.1 2454900 R 508767 CDS YP_001921672.1 188590194 6319616 complement(2455133..2456176) 1 NC_010723.1 D-galactose-binding periplasmic protein 2456176 6319616 CLH_2291 Clostridium botulinum E3 str. Alaska E43 D-galactose-binding periplasmic protein YP_001921672.1 2455133 R 508767 CDS YP_001921673.1 188590554 6317729 complement(2456429..2456851) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2456851 6317729 CLH_2292 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921673.1 2456429 R 508767 CDS YP_001921674.1 188589599 6318121 complement(2457001..2461305) 1 NC_010723.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; CoA-substrate-specific enzyme activase domain-containing protein 2461305 6318121 CLH_2293 Clostridium botulinum E3 str. Alaska E43 CoA-substrate-specific enzyme activase domain-containing protein YP_001921674.1 2457001 R 508767 CDS YP_001921675.1 188589076 6320196 2461503..2461856 1 NC_010723.1 identified by match to protein family HMM PF00515; tetratricopeptide repeat protein 2461856 6320196 CLH_2294 Clostridium botulinum E3 str. Alaska E43 tetratricopeptide repeat protein YP_001921675.1 2461503 D 508767 CDS YP_001921676.1 188588223 6318512 complement(2461906..2462970) 1 NC_010723.1 identified by match to protein family HMM PF01841; transglutaminase domain protein 2462970 6318512 CLH_2295 Clostridium botulinum E3 str. Alaska E43 transglutaminase domain protein YP_001921676.1 2461906 R 508767 CDS YP_001921677.1 188590124 6319653 complement(2462983..2463621) 1 NC_010723.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2463621 recX 6319653 recX Clostridium botulinum E3 str. Alaska E43 recombination regulator RecX YP_001921677.1 2462983 R 508767 CDS YP_001921678.1 188589266 6317485 complement(2463721..2464962) 1 NC_010723.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family 2464962 6317485 CLH_2297 Clostridium botulinum E3 str. Alaska E43 peptidase, M16 family YP_001921678.1 2463721 R 508767 CDS YP_001921679.1 188590060 6318597 2465168..2465839 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulatory protein ResD 2465839 6318597 CLH_2298 Clostridium botulinum E3 str. Alaska E43 transcriptional regulatory protein ResD YP_001921679.1 2465168 D 508767 CDS YP_001921680.1 188589604 6320430 2465839..2467347 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01563; two-component sensor histidine kinase 2467347 6320430 CLH_2299 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001921680.1 2465839 D 508767 CDS YP_001921681.1 188588709 6317362 complement(2467374..2469353) 1 NC_010723.1 identified by match to protein family HMM PF06874; fructose-1,6-bisphosphatase 2469353 fbp 6317362 fbp Clostridium botulinum E3 str. Alaska E43 fructose-1,6-bisphosphatase YP_001921681.1 2467374 R 508767 CDS YP_001921682.1 188588539 6318132 complement(2469736..2470596) 1 NC_010723.1 identified by match to protein family HMM PF01134; match to protein family HMM PF07992; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2470596 gidA 6318132 gidA Clostridium botulinum E3 str. Alaska E43 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001921682.1 2469736 R 508767 CDS YP_001921683.1 188587717 6318720 complement(2470614..2470928) 1 NC_010723.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2470928 trx 6318720 trx Clostridium botulinum E3 str. Alaska E43 thioredoxin YP_001921683.1 2470614 R 508767 CDS YP_001921684.1 188590341 6319125 2471572..2472132 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2472132 6319125 CLH_2303 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921684.1 2471572 D 508767 CDS YP_001921685.1 188589423 6318774 complement(2472224..2473930) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; lipid A export ATP-binding/permease protein MsbA 2473930 6318774 CLH_2304 Clostridium botulinum E3 str. Alaska E43 lipid A export ATP-binding/permease protein MsbA YP_001921685.1 2472224 R 508767 CDS YP_001921686.1 188588857 6317750 complement(2473964..2474635) 1 NC_010723.1 identified by match to protein family HMM PF00005; aliphatic sulfonates import ATP-binding protein SsuB 2474635 6317750 CLH_2305 Clostridium botulinum E3 str. Alaska E43 aliphatic sulfonates import ATP-binding protein SsuB YP_001921686.1 2473964 R 508767 CDS YP_001921687.1 188588009 6317760 complement(2474619..2475389) 1 NC_010723.1 identified by match to protein family HMM PF00528; ABC transporter permease 2475389 6317760 CLH_2306 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001921687.1 2474619 R 508767 CDS YP_001921688.1 188590134 6319528 complement(2475364..2476344) 1 NC_010723.1 ABC transporter substrate-binding protein 2476344 6319528 CLH_2307 Clostridium botulinum E3 str. Alaska E43 ABC transporter substrate-binding protein YP_001921688.1 2475364 R 508767 CDS YP_001921689.1 188588951 6317736 complement(2476665..2477084) 1 NC_010723.1 identified by match to protein family HMM PF03885; hypothetical protein 2477084 6317736 CLH_2308 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921689.1 2476665 R 508767 CDS YP_001921690.1 188588689 6318415 2477255..2477554 1 NC_010723.1 hypothetical protein 2477554 6318415 CLH_2309 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921690.1 2477255 D 508767 CDS YP_001921691.1 188588744 6318130 complement(2477699..2479543) 1 NC_010723.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536; asparagine synthase 2479543 asnB 6318130 asnB Clostridium botulinum E3 str. Alaska E43 asparagine synthase YP_001921691.1 2477699 R 508767 CDS YP_001921692.1 188589228 6317459 2479799..2481202 1 NC_010723.1 identified by match to protein family HMM PF03323; stage V sporulation protein AF 2481202 6317459 CLH_2311 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein AF YP_001921692.1 2479799 D 508767 CDS YP_001921693.1 188587980 6320372 complement(2481319..2482155) 1 NC_010723.1 S1 RNA binding domain 2482155 6320372 CLH_2312 Clostridium botulinum E3 str. Alaska E43 S1 RNA binding domain YP_001921693.1 2481319 R 508767 CDS YP_001921694.1 188587822 6318889 complement(2482179..2482688) 1 NC_010723.1 identified by match to protein family HMM PF00132; ferripyochelin binding protein 2482688 6318889 CLH_2313 Clostridium botulinum E3 str. Alaska E43 ferripyochelin binding protein YP_001921694.1 2482179 R 508767 CDS YP_001921695.1 188589857 6320582 2483016..2483825 1 NC_010723.1 hypothetical protein 2483825 6320582 CLH_2314 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921695.1 2483016 D 508767 CDS YP_001921696.1 188590773 6320126 complement(2484010..2484129) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2484129 6320126 CLH_2315 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921696.1 2484010 R 508767 CDS YP_001921697.1 188587619 6317855 complement(2484189..2484524) 1 NC_010723.1 hypothetical protein 2484524 6317855 CLH_2316 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921697.1 2484189 R 508767 CDS YP_001921698.1 188587811 6319413 2484753..2485220 1 NC_010723.1 identified by match to protein family HMM PF01037; transcriptional regulator, AsnC family 2485220 6319413 CLH_2317 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, AsnC family YP_001921698.1 2484753 D 508767 CDS YP_001921699.1 188590570 6319512 2485299..2485499 1 NC_010723.1 identified by match to protein family HMM PF04070; hypothetical protein 2485499 6319512 CLH_2318 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921699.1 2485299 D 508767 CDS YP_001921700.1 188589644 6317875 2485644..2486405 1 NC_010723.1 identified by match to protein family HMM PF06541; hypothetical protein 2486405 6317875 CLH_2319 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921700.1 2485644 D 508767 CDS YP_001921701.1 188588991 6320078 complement(2486456..2488207) 1 NC_010723.1 hypothetical protein 2488207 6320078 CLH_2320 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921701.1 2486456 R 508767 CDS YP_001921702.1 188588153 6319106 2488426..2489292 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 2489292 6319106 CLH_2321 Clostridium botulinum E3 str. Alaska E43 metallo-beta-lactamase family protein YP_001921702.1 2488426 D 508767 CDS YP_001921703.1 188589290 6318920 2489447..2490904 1 NC_010723.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2490904 gltX 6318920 gltX Clostridium botulinum E3 str. Alaska E43 glutamyl-tRNA synthetase YP_001921703.1 2489447 D 508767 CDS YP_001921704.1 188588372 6320410 complement(2491044..2491799) 1 NC_010723.1 hypothetical protein 2491799 6320410 CLH_2323 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921704.1 2491044 R 508767 CDS YP_001921705.1 188587880 6319980 complement(2491814..2492542) 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; HAD-superfamily hydrolase 2492542 6319980 CLH_2324 Clostridium botulinum E3 str. Alaska E43 HAD-superfamily hydrolase YP_001921705.1 2491814 R 508767 CDS YP_001921706.1 188590572 6317387 2492772..2492993 1 NC_010723.1 identified by match to protein family HMM PF04023; hypothetical protein 2492993 6317387 CLH_2325 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921706.1 2492772 D 508767 CDS YP_001921707.1 188589655 6317877 2493008..2494771 1 NC_010723.1 identified by match to protein family HMM PF01926; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; match to protein family HMM TIGR00231; match to protein family HMM TIGR00437; match to protein family HMM TIGR00650; ferrous iron transport protein B 2494771 feoB 6317877 feoB Clostridium botulinum E3 str. Alaska E43 ferrous iron transport protein B YP_001921707.1 2493008 D 508767 CDS YP_001921708.1 188589338 6320385 complement(2495145..2496257) 1 NC_010723.1 identified by match to protein family HMM PF01594; permease 2496257 6320385 CLH_2327 Clostridium botulinum E3 str. Alaska E43 permease YP_001921708.1 2495145 R 508767 CDS YP_001921709.1 188588753 6318837 complement(2496539..2498230) 1 NC_010723.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2498230 argS 6318837 argS Clostridium botulinum E3 str. Alaska E43 arginyl-tRNA synthetase YP_001921709.1 2496539 R 508767 CDS YP_001921710.1 188589250 6317468 2498789..2500294 1 NC_010723.1 identified by match to protein family HMM PF02541; Ppx/GppA phosphatase family protein 2500294 6317468 CLH_2329 Clostridium botulinum E3 str. Alaska E43 Ppx/GppA phosphatase family protein YP_001921710.1 2498789 D 508767 CDS YP_001921711.1 188590549 6317686 complement(2500425..2501063) 1 NC_010723.1 identified by match to protein family HMM PF02163; peptidase, M50 family 2501063 6317686 CLH_2330 Clostridium botulinum E3 str. Alaska E43 peptidase, M50 family YP_001921711.1 2500425 R 508767 CDS YP_001921712.1 188588021 6317984 complement(2501305..2502336) 1 NC_010723.1 hypothetical protein 2502336 6317984 CLH_2331 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921712.1 2501305 R 508767 CDS YP_001921713.1 188589071 6319850 complement(2502355..2503398) 1 NC_010723.1 hypothetical protein 2503398 6319850 CLH_2332 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921713.1 2502355 R 508767 CDS YP_001921714.1 188589802 6319442 2503653..2504621 1 NC_010723.1 identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM PF08279; match to protein family HMM TIGR00121; biotin-[acetyl-CoA-carboxylase] ligase 2504621 6319442 CLH_2333 Clostridium botulinum E3 str. Alaska E43 biotin-[acetyl-CoA-carboxylase] ligase YP_001921714.1 2503653 D 508767 CDS YP_001921715.1 188587650 6319428 complement(2504855..2505868) 1 NC_010723.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 2505868 asnA 6319428 asnA Clostridium botulinum E3 str. Alaska E43 asparagine synthetase AsnA YP_001921715.1 2504855 R 508767 CDS YP_001921716.1 188588359 6319957 complement(2506027..2506977) 1 NC_010723.1 identified by match to protein family HMM PF00056; match to protein family HMM PF02866; match to protein family HMM TIGR01771; L-lactate dehydrogenase 2506977 6319957 CLH_2335 Clostridium botulinum E3 str. Alaska E43 L-lactate dehydrogenase YP_001921716.1 2506027 R 508767 CDS YP_001921717.1 188587656 6319639 2507347..2507961 1 NC_010723.1 identified by match to protein family HMM PF00929; exonuclease 2507961 6319639 CLH_2336 Clostridium botulinum E3 str. Alaska E43 exonuclease YP_001921717.1 2507347 D 508767 CDS YP_001921718.1 188588672 6319612 2508151..2508312 1 NC_010723.1 identified by match to protein family HMM PF00301; rubredoxin 2508312 6319612 CLH_2337 Clostridium botulinum E3 str. Alaska E43 rubredoxin YP_001921718.1 2508151 D 508767 CDS YP_001921719.1 188589411 6318819 complement(2508512..2509222) 1 NC_010723.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493; pyruvate formate-lyase 1-activating enzyme 2509222 pflA 6318819 pflA Clostridium botulinum E3 str. Alaska E43 pyruvate formate-lyase 1-activating enzyme YP_001921719.1 2508512 R 508767 CDS YP_001921720.1 188590176 6320446 complement(2509385..2511613) 1 NC_010723.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 2511613 pflB 6320446 pflB Clostridium botulinum E3 str. Alaska E43 formate acetyltransferase YP_001921720.1 2509385 R 508767 CDS YP_001921721.1 188588533 6318643 2512039..2513415 1 NC_010723.1 hypothetical protein 2513415 6318643 CLH_2340 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921721.1 2512039 D 508767 CDS YP_001921722.1 188589452 6318484 complement(2513561..2514235) 1 NC_010723.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 2514235 pyrE 6318484 pyrE Clostridium botulinum E3 str. Alaska E43 orotate phosphoribosyltransferase YP_001921722.1 2513561 R 508767 CDS YP_001921723.1 188590377 6319059 complement(2514284..2515180) 1 NC_010723.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 2515180 pyrD 6319059 pyrD Clostridium botulinum E3 str. Alaska E43 dihydroorotate dehydrogenase 1B YP_001921723.1 2514284 R 508767 CDS YP_001921724.1 188588810 6318053 complement(2515202..2515945) 1 NC_010723.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 2515945 6318053 CLH_2343 Clostridium botulinum E3 str. Alaska E43 dihydroorotate dehydrogenase electron transfer subunit YP_001921724.1 2515202 R 508767 CDS YP_001921725.1 188587972 6319302 complement(2515959..2516831) 1 NC_010723.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2516831 pyrF 6319302 pyrF Clostridium botulinum E3 str. Alaska E43 orotidine 5'-phosphate decarboxylase YP_001921725.1 2515959 R 508767 CDS YP_001921726.1 188588933 6317536 complement(2516943..2518139) 1 NC_010723.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR00857; dihydroorotase, multifunctional complex type 2518139 6317536 CLH_2345 Clostridium botulinum E3 str. Alaska E43 dihydroorotase, multifunctional complex type YP_001921726.1 2516943 R 508767 CDS YP_001921727.1 188589885 6317673 complement(2518164..2518595) 1 NC_010723.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 2518595 6317673 CLH_2346 Clostridium botulinum E3 str. Alaska E43 aspartate carbamoyltransferase regulatory subunit YP_001921727.1 2518164 R 508767 CDS YP_001921728.1 188590766 6319231 complement(2518597..2519520) 1 NC_010723.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 2519520 pyrB 6319231 pyrB Clostridium botulinum E3 str. Alaska E43 aspartate carbamoyltransferase catalytic subunit YP_001921728.1 2518597 R 508767 CDS YP_001921729.1 188588358 6320239 complement(2520083..2520940) 1 NC_010723.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 2520940 uppP 6320239 uppP Clostridium botulinum E3 str. Alaska E43 undecaprenyl pyrophosphate phosphatase YP_001921729.1 2520083 R 508767 CDS YP_001921730.1 188589153 6319638 complement(2521007..2522134) 1 NC_010723.1 hypothetical protein 2522134 6319638 CLH_2349 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921730.1 2521007 R 508767 CDS YP_001921731.1 188590349 6319378 complement(2522298..2524067) 1 NC_010723.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 2524067 6319378 CLH_2350 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921731.1 2522298 R 508767 CDS YP_001921732.1 188589309 6317406 2524263..2525624 1 NC_010723.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353; Mur ligase family protein 2525624 6317406 CLH_2351 Clostridium botulinum E3 str. Alaska E43 Mur ligase family protein YP_001921732.1 2524263 D 508767 CDS YP_001921733.1 188590352 6317457 2525643..2526374 1 NC_010723.1 identified by match to protein family HMM PF07685; CobB/CobQ family glutamine amidotransferase 2526374 6317457 CLH_2352 Clostridium botulinum E3 str. Alaska E43 CobB/CobQ family glutamine amidotransferase YP_001921733.1 2525643 D 508767 CDS YP_001921734.1 188589407 6320480 complement(2526450..2527196) 1 NC_010723.1 identified by match to protein family HMM PF01522; peptidoglycan N-acetylglucosamine deacetylase 2527196 6320480 CLH_2353 Clostridium botulinum E3 str. Alaska E43 peptidoglycan N-acetylglucosamine deacetylase YP_001921734.1 2526450 R 508767 CDS YP_001921735.1 188588906 6319102 2527439..2528716 1 NC_010723.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 2528716 6319102 CLH_2354 Clostridium botulinum E3 str. Alaska E43 D-alanyl-D-alanine carboxypeptidase YP_001921735.1 2527439 D 508767 CDS YP_001921736.1 188588037 6318366 2528776..2529375 1 NC_010723.1 identified by match to protein family HMM PF01613; flavoredoxin 2529375 6318366 CLH_2355 Clostridium botulinum E3 str. Alaska E43 flavoredoxin YP_001921736.1 2528776 D 508767 CDS YP_001921737.1 188590781 6319220 complement(2529548..2529886) 1 NC_010723.1 identified by match to protein family HMM PF03960; ArsC family 2529886 6319220 CLH_2356 Clostridium botulinum E3 str. Alaska E43 ArsC family YP_001921737.1 2529548 R 508767 CDS YP_001921738.1 188589676 6319099 2530102..2531055 1 NC_010723.1 putative acyltransferase 2531055 6319099 CLH_2357 Clostridium botulinum E3 str. Alaska E43 putative acyltransferase YP_001921738.1 2530102 D 508767 CDS YP_001921739.1 188589110 6319349 complement(2531094..2531741) 1 NC_010723.1 identified by match to protein family HMM PF09335; DedA family membrane protein 2531741 6319349 CLH_2358 Clostridium botulinum E3 str. Alaska E43 DedA family membrane protein YP_001921739.1 2531094 R 508767 CDS YP_001921740.1 188587963 6320490 complement(2531858..2533195) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 2533195 6320490 CLH_2359 Clostridium botulinum E3 str. Alaska E43 mate efflux family protein YP_001921740.1 2531858 R 508767 CDS YP_001921741.1 188588426 6317367 complement(2533547..2535310) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspA 2535310 6317367 CLH_2360 Clostridium botulinum E3 str. Alaska E43 surface protein PspA YP_001921741.1 2533547 R 508767 CDS YP_001921742.1 188587740 6318902 2535733..2536605 1 NC_010723.1 identified by match to protein family HMM PF03767; match to protein family HMM TIGR01533; 5'-nucleotidase 2536605 6318902 CLH_2361 Clostridium botulinum E3 str. Alaska E43 5'-nucleotidase YP_001921742.1 2535733 D 508767 CDS YP_001921743.1 188590298 6319748 complement(2536734..2538416) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis sensory transducer 2538416 6319748 CLH_2362 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis sensory transducer YP_001921743.1 2536734 R 508767 CDS YP_001921744.1 188589503 6320350 2538944..2540605 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 2540605 6320350 CLH_2363 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001921744.1 2538944 D 508767 CDS YP_001921745.1 188588082 6318683 complement(2540727..2541308) 1 NC_010723.1 identified by match to protein family HMM PF00132; chloramphenicol acetyltransferase 2541308 6318683 CLH_2364 Clostridium botulinum E3 str. Alaska E43 chloramphenicol acetyltransferase YP_001921745.1 2540727 R 508767 CDS YP_001921746.1 188590226 6319275 2541880..2543052 1 NC_010723.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 2543052 6319275 CLH_2365 Clostridium botulinum E3 str. Alaska E43 sodium:dicarboxylate symporter family protein YP_001921746.1 2541880 D 508767 CDS YP_001921747.1 188589925 6317293 2543389..2543784 1 NC_010723.1 hypothetical protein 2543784 6317293 CLH_2366 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921747.1 2543389 D 508767 CDS YP_001921748.1 188589308 6318424 complement(2543866..2544372) 1 NC_010723.1 hypothetical protein 2544372 6318424 CLH_2367 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921748.1 2543866 R 508767 CDS YP_001921749.1 188589262 6317513 complement(2544595..2544891) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2544891 6317513 CLH_2368 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921749.1 2544595 R 508767 CDS YP_001921750.1 188590017 6318570 complement(2544947..2545240) 1 NC_010723.1 hypothetical protein 2545240 6318570 CLH_2369 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921750.1 2544947 R 508767 CDS YP_001921751.1 188590551 6319661 complement(2545390..2545557) 1 NC_010723.1 DNA polymerase, beta domain-containing protein region 2545557 6319661 CLH_2370 Clostridium botulinum E3 str. Alaska E43 DNA polymerase, beta domain-containing protein region YP_001921751.1 2545390 R 508767 CDS YP_001921752.1 188588762 6318815 complement(2545766..2546458) 1 NC_010723.1 filamentation induced by cAMP protein fic 2546458 6318815 CLH_2371 Clostridium botulinum E3 str. Alaska E43 filamentation induced by cAMP protein fic YP_001921752.1 2545766 R 508767 CDS YP_001921753.1 188589633 6319096 complement(2546684..2546797) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2546797 6319096 CLH_2372 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921753.1 2546684 R 508767 CDS YP_001921754.1 188590518 6318473 complement(2546840..2547145) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2547145 6318473 CLH_2373 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921754.1 2546840 R 508767 CDS YP_001921755.1 188588204 6320171 2547290..2547571 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2547571 6320171 CLH_2374 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921755.1 2547290 D 508767 CDS YP_001921756.1 188588495 6319515 2547591..2547830 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2547830 6319515 CLH_2375 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921756.1 2547591 D 508767 CDS YP_001921757.1 188588677 6320259 complement(2548473..2548934) 1 NC_010723.1 identified by match to protein family HMM PF00583; spermine/spermidine acetyltransferase 2548934 6320259 CLH_2376 Clostridium botulinum E3 str. Alaska E43 spermine/spermidine acetyltransferase YP_001921757.1 2548473 R 508767 CDS YP_001921758.1 188590054 6317505 2549300..2550292 1 NC_010723.1 identified by match to protein family HMM PF02275; penicillin acylase 2550292 6317505 CLH_2377 Clostridium botulinum E3 str. Alaska E43 penicillin acylase YP_001921758.1 2549300 D 508767 CDS YP_001921759.1 188589805 6320556 complement(2550524..2551864) 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inner membrane protein YicO 2551864 6320556 CLH_2378 Clostridium botulinum E3 str. Alaska E43 inner membrane protein YicO YP_001921759.1 2550524 R 508767 CDS YP_001921760.1 188588879 6320114 complement(2552463..2552696) 1 NC_010723.1 hypothetical protein 2552696 6320114 CLH_2379 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921760.1 2552463 R 508767 CDS YP_001921761.1 188588919 6318987 complement(2552698..2553183) 1 NC_010723.1 hypothetical protein 2553183 6318987 CLH_2380 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921761.1 2552698 R 508767 CDS YP_001921762.1 188588011 6319109 complement(2553180..2553407) 1 NC_010723.1 hypothetical protein 2553407 6319109 CLH_2381 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921762.1 2553180 R 508767 CDS YP_001921763.1 188589586 6319530 2553821..2554849 1 NC_010723.1 ABC transporter substrate-binding protein 2554849 6319530 CLH_2382 Clostridium botulinum E3 str. Alaska E43 ABC transporter substrate-binding protein YP_001921763.1 2553821 D 508767 CDS YP_001921764.1 188588558 6318776 2554869..2555636 1 NC_010723.1 identified by match to protein family HMM PF00005; aliphatic sulfonates import ATP-binding protein SsuB 2555636 6318776 CLH_2383 Clostridium botulinum E3 str. Alaska E43 aliphatic sulfonates import ATP-binding protein SsuB YP_001921764.1 2554869 D 508767 CDS YP_001921765.1 188590106 6320195 2555629..2556429 1 NC_010723.1 identified by match to protein family HMM PF00528; ABC transporter permease 2556429 6320195 CLH_2384 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001921765.1 2555629 D 508767 CDS YP_001921766.1 188589331 6317496 2556671..2557057 1 NC_010723.1 identified by match to protein family HMM PF03788; LrgA family protein 2557057 6317496 CLH_2385 Clostridium botulinum E3 str. Alaska E43 LrgA family protein YP_001921766.1 2556671 D 508767 CDS YP_001921767.1 188588616 6318977 2557041..2557754 1 NC_010723.1 identified by match to protein family HMM PF04172; LrgB family protein 2557754 6318977 CLH_2386 Clostridium botulinum E3 str. Alaska E43 LrgB family protein YP_001921767.1 2557041 D 508767 CDS YP_001921768.1 188588678 6317671 complement(2558194..2560350) 1 NC_010723.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01751; DNA topoisomerase 2560350 6317671 CLH_2387 Clostridium botulinum E3 str. Alaska E43 DNA topoisomerase YP_001921768.1 2558194 R 508767 CDS YP_001921769.1 188590396 6317506 complement(2560500..2561000) 1 NC_010723.1 identified by match to protein family HMM PF03073; TspO/MBR family protein 2561000 6317506 CLH_2388 Clostridium botulinum E3 str. Alaska E43 TspO/MBR family protein YP_001921769.1 2560500 R 508767 CDS YP_001921770.1 188588069 6318013 complement(2561100..2561216) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2561216 6318013 CLH_2389 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921770.1 2561100 R 508767 CDS YP_001921771.1 188589034 6318991 complement(2561282..2563297) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensory box histidine kinase 2563297 6318991 CLH_2390 Clostridium botulinum E3 str. Alaska E43 sensory box histidine kinase YP_001921771.1 2561282 R 508767 CDS YP_001921772.1 188589921 6320368 complement(2563299..2564621) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 2564621 6320368 CLH_2391 Clostridium botulinum E3 str. Alaska E43 sensor histidine kinase YP_001921772.1 2563299 R 508767 CDS YP_001921773.1 188588257 6319394 complement(2565498..2567780) 1 NC_010723.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062; phage infection protein 2567780 6319394 CLH_2392 Clostridium botulinum E3 str. Alaska E43 phage infection protein YP_001921773.1 2565498 R 508767 CDS YP_001921774.1 188589062 6319881 complement(2567792..2570065) 1 NC_010723.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062; phage infection protein 2570065 6319881 CLH_2393 Clostridium botulinum E3 str. Alaska E43 phage infection protein YP_001921774.1 2567792 R 508767 CDS YP_001921775.1 188588601 6320231 complement(2570624..2571736) 1 NC_010723.1 identified by match to protein family HMM PF01270; glycosyl hydrolase family protein 2571736 6320231 CLH_2394 Clostridium botulinum E3 str. Alaska E43 glycosyl hydrolase family protein YP_001921775.1 2570624 R 508767 CDS YP_001921776.1 188589229 6318163 complement(2571777..2572343) 1 NC_010723.1 identified by match to protein family HMM PF01464; transglycosylase 2572343 6318163 CLH_2395 Clostridium botulinum E3 str. Alaska E43 transglycosylase YP_001921776.1 2571777 R 508767 CDS YP_001921777.1 188587853 6320482 complement(2572587..2573183) 1 NC_010723.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 2573183 coaE 6320482 coaE Clostridium botulinum E3 str. Alaska E43 dephospho-CoA kinase YP_001921777.1 2572587 R 508767 CDS YP_001921778.1 188589036 6317658 complement(2573206..2575821) 1 NC_010723.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 2575821 polA 6317658 polA Clostridium botulinum E3 str. Alaska E43 DNA polymerase I YP_001921778.1 2573206 R 508767 CDS YP_001921779.1 188588567 6318844 2576327..2577556 1 NC_010723.1 identified by match to protein family HMM PF02073; aminopeptidase II 2577556 6318844 CLH_2398 Clostridium botulinum E3 str. Alaska E43 aminopeptidase II YP_001921779.1 2576327 D 508767 CDS YP_001921780.1 188587899 6319144 complement(2577881..2578018) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2578018 6319144 CLH_2399 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921780.1 2577881 R 508767 CDS YP_001921781.1 188589342 6317310 complement(2578112..2578633) 1 NC_010723.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2578633 dcd 6317310 dcd Clostridium botulinum E3 str. Alaska E43 deoxycytidine triphosphate deaminase YP_001921781.1 2578112 R 508767 CDS YP_001921782.1 188588585 6317248 complement(2578926..2580134) 1 NC_010723.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 2580134 6317248 CLH_2401 Clostridium botulinum E3 str. Alaska E43 isocitrate dehydrogenase YP_001921782.1 2578926 R 508767 CDS YP_001921783.1 188587909 6318671 complement(2580271..2581281) 1 NC_010723.1 identified by match to protein family HMM PF03601; membrane protein 2581281 6318671 CLH_2402 Clostridium botulinum E3 str. Alaska E43 membrane protein YP_001921783.1 2580271 R 508767 CDS YP_001921784.1 188590286 6317422 complement(2581407..2582282) 1 NC_010723.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR-family transcriptional regulator 2582282 6317422 CLH_2403 Clostridium botulinum E3 str. Alaska E43 LysR-family transcriptional regulator YP_001921784.1 2581407 R 508767 CDS YP_001921785.1 188588834 6320600 complement(2582583..2583743) 1 NC_010723.1 identified by match to protein family HMM PF01098; stage V sporulation protein E 2583743 6320600 CLH_2404 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein E YP_001921785.1 2582583 R 508767 CDS YP_001921786.1 188588089 6317900 complement(2584101..2584640) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2584640 6317900 CLH_2405 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921786.1 2584101 R 508767 CDS YP_001921787.1 188590661 6320023 complement(2584686..2585153) 1 NC_010723.1 identified by match to protein family HMM PF00583; putative acetyltransferase 2585153 6320023 CLH_2406 Clostridium botulinum E3 str. Alaska E43 putative acetyltransferase YP_001921787.1 2584686 R 508767 CDS YP_001921788.1 188589398 6318455 complement(2585866..2585979) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2585979 6318455 CLH_2407 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921788.1 2585866 R 508767 CDS YP_001921789.1 188588496 6318665 complement(2586206..2586403) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2586403 6318665 CLH_2408 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921789.1 2586206 R 508767 CDS YP_001921790.1 188587583 6320260 complement(2586515..2586628) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2586628 6320260 CLH_2409 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921790.1 2586515 R 508767 CDS YP_001921791.1 188590481 6318010 2587128..2587496 1 NC_010723.1 identified by match to protein family HMM PF06953; arsenical resistance operon trans-acting repressor ArsD 2587496 6318010 CLH_2410 Clostridium botulinum E3 str. Alaska E43 arsenical resistance operon trans-acting repressor ArsD YP_001921791.1 2587128 D 508767 CDS YP_001921792.1 188589384 6318269 2587557..2589305 1 NC_010723.1 identified by match to protein family HMM PF02374; match to protein family HMM TIGR00345; arsenical pump-driving ATPase ArsA 2589305 arsA 6318269 arsA Clostridium botulinum E3 str. Alaska E43 arsenical pump-driving ATPase ArsA YP_001921792.1 2587557 D 508767 CDS YP_001921793.1 188589046 6318219 complement(2589419..2589883) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2589883 6318219 CLH_2412 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921793.1 2589419 R 508767 CDS YP_001921794.1 188587976 6319950 complement(2590313..2590612) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2590612 6319950 CLH_2413 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921794.1 2590313 R 508767 CDS YP_001921795.1 188589267 6317551 complement(2590971..2591816) 1 NC_010723.1 putative lipoprotein 2591816 6317551 CLH_2414 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921795.1 2590971 R 508767 CDS YP_001921796.1 188589842 6318705 complement(2592206..2593975) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; membrane associated methyl-accepting chemotaxis protein with hamp domain 2593975 6318705 CLH_2415 Clostridium botulinum E3 str. Alaska E43 membrane associated methyl-accepting chemotaxis protein with hamp domain YP_001921796.1 2592206 R 508767 CDS YP_001921797.1 188587812 6320128 2594440..2595732 1 NC_010723.1 identified by match to protein family HMM PF01547; maltose-binding protein 2595732 6320128 CLH_2416 Clostridium botulinum E3 str. Alaska E43 maltose-binding protein YP_001921797.1 2594440 D 508767 CDS YP_001921798.1 188590473 6319992 2595984..2596850 1 NC_010723.1 identified by match to protein family HMM PF00528; ABC transporter permease 2596850 6319992 CLH_2417 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001921798.1 2595984 D 508767 CDS YP_001921799.1 188588826 6320440 2596850..2597755 1 NC_010723.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 2597755 6320440 CLH_2418 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter permease YP_001921799.1 2596850 D 508767 CDS YP_001921800.1 188589492 6318183 complement(2597984..2598865) 1 NC_010723.1 identified by match to protein family HMM PF07885; Ion channel family 2598865 6318183 CLH_2419 Clostridium botulinum E3 str. Alaska E43 Ion channel family YP_001921800.1 2597984 R 508767 CDS YP_001921801.1 188590279 6320251 complement(2598883..2599569) 1 NC_010723.1 hypothetical protein 2599569 6320251 CLH_2420 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921801.1 2598883 R 508767 CDS YP_001921802.1 188587715 6320185 complement(2599775..2601808) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 2601808 6320185 CLH_2421 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001921802.1 2599775 R 508767 CDS YP_001921803.1 188589296 6317238 complement(2602156..2604204) 1 NC_010723.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01520; surface protein PspC 2604204 6317238 CLH_2422 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001921803.1 2602156 R 508767 CDS YP_001921804.1 188589944 6320522 complement(2604513..2605142) 1 NC_010723.1 identified by match to protein family HMM PF07238; type IV pilus assembly protein PilZ 2605142 6320522 CLH_2423 Clostridium botulinum E3 str. Alaska E43 type IV pilus assembly protein PilZ YP_001921804.1 2604513 R 508767 CDS YP_001921805.1 188590656 6319722 2605600..2606187 1 NC_010723.1 identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; sigma-70 region 2 domain-containing protein 2606187 6319722 CLH_2424 Clostridium botulinum E3 str. Alaska E43 sigma-70 region 2 domain-containing protein YP_001921805.1 2605600 D 508767 CDS YP_001921806.1 188588071 6319280 complement(2606241..2606354) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2606354 6319280 CLH_2425 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921806.1 2606241 R 508767 CDS YP_001921807.1 188589735 6319017 complement(2606508..2607788) 1 NC_010723.1 identified by match to protein family HMM PF02588; integral membrane protein 2607788 6319017 CLH_2426 Clostridium botulinum E3 str. Alaska E43 integral membrane protein YP_001921807.1 2606508 R 508767 CDS YP_001921808.1 188589930 6319693 complement(2607788..2608216) 1 NC_010723.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2608216 6319693 CLH_2427 Clostridium botulinum E3 str. Alaska E43 MarR family transcriptional regulator YP_001921808.1 2607788 R 508767 CDS YP_001921809.1 188589916 6319505 2608768..2608965 1 NC_010723.1 hypothetical protein 2608965 6319505 CLH_2428 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921809.1 2608768 D 508767 CDS YP_001921810.1 188590635 6317517 complement(2609115..2610179) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2610179 6317517 CLH_2429 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921810.1 2609115 R 508767 CDS YP_001921811.1 188587600 6318149 complement(2610278..2610790) 1 NC_010723.1 identified by match to protein family HMM PF04229; hypothetical protein 2610790 6318149 CLH_2430 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921811.1 2610278 R 508767 CDS YP_001921812.1 188588747 6319690 complement(2610821..2611609) 1 NC_010723.1 identified by match to protein family HMM PF02698; hypothetical protein 2611609 6319690 CLH_2431 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921812.1 2610821 R 508767 CDS YP_001921813.1 188590300 6317450 complement(2611671..2611874) 1 NC_010723.1 hypothetical protein 2611874 6317450 CLH_2432 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921813.1 2611671 R 508767 CDS YP_001921814.1 188588928 6317954 complement(2612017..2612988) 1 NC_010723.1 identified by match to protein family HMM PF07282; match to protein family HMM TIGR01766; transposase, family 2612988 6317954 CLH_2433 Clostridium botulinum E3 str. Alaska E43 transposase, family YP_001921814.1 2612017 R 508767 CDS YP_001921815.1 188589899 6320414 complement(2612978..2613127) 1 NC_010723.1 resolvase, N- domain 2613127 6320414 CLH_2434 Clostridium botulinum E3 str. Alaska E43 resolvase, N- domain YP_001921815.1 2612978 R 508767 CDS YP_001921816.1 188590657 6319519 complement(2613322..2613756) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2613756 6319519 CLH_2435 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921816.1 2613322 R 508767 CDS YP_001921817.1 188590644 6319281 complement(2613893..2614288) 1 NC_010723.1 hypothetical protein 2614288 6319281 CLH_2436 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921817.1 2613893 R 508767 CDS YP_001921818.1 188590142 6319294 2614645..2614812 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2614812 6319294 CLH_2438 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921818.1 2614645 D 508767 CDS YP_001921819.1 188590424 6317259 complement(2614809..2614991) 1 NC_010723.1 hypothetical protein 2614991 6317259 CLH_2437 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921819.1 2614809 R 508767 CDS YP_001921820.1 188588320 6320041 complement(2615111..2616040) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2616040 6320041 CLH_2439 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921820.1 2615111 R 508767 CDS YP_001921821.1 188588718 6319949 complement(2616033..2616605) 1 NC_010723.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; specialized sigma subunit of RNA polymerase 2616605 6319949 CLH_2440 Clostridium botulinum E3 str. Alaska E43 specialized sigma subunit of RNA polymerase YP_001921821.1 2616033 R 508767 CDS YP_001921822.1 188589472 6317807 complement(2616955..2617818) 1 NC_010723.1 identified by match to protein family HMM PF01210; match to protein family HMM PF03446; match to protein family HMM PF03807; putative 2-hydroxy-3-oxopropionate reductase 2617818 6317807 CLH_2441 Clostridium botulinum E3 str. Alaska E43 putative 2-hydroxy-3-oxopropionate reductase YP_001921822.1 2616955 R 508767 CDS YP_001921823.1 188590393 6317825 complement(2618027..2618563) 1 NC_010723.1 transcriptional regulator NfxB 2618563 6317825 CLH_2442 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator NfxB YP_001921823.1 2618027 R 508767 CDS YP_001921824.1 188588825 6317548 complement(2618847..2619605) 1 NC_010723.1 identified by match to protein family HMM PF08241; methyltransferase domain-containing protein 2619605 6317548 CLH_2443 Clostridium botulinum E3 str. Alaska E43 methyltransferase domain-containing protein YP_001921824.1 2618847 R 508767 CDS YP_001921825.1 188589796 6318716 complement(2619823..2620593) 1 NC_010723.1 identified by match to protein family HMM PF08241; methyltransferase 2620593 6318716 CLH_2444 Clostridium botulinum E3 str. Alaska E43 methyltransferase YP_001921825.1 2619823 R 508767 CDS YP_001921826.1 188590735 6317391 complement(2621018..2621347) 1 NC_010723.1 identified by match to protein family HMM PF04993; TfoX N- domain family protein 2621347 6317391 CLH_2445 Clostridium botulinum E3 str. Alaska E43 TfoX N- domain family protein YP_001921826.1 2621018 R 508767 CDS YP_001921827.1 188589808 6318812 complement(2621372..2621761) 1 NC_010723.1 identified by match to protein family HMM PF00903; glyoxalase family protein 2621761 6318812 CLH_2446 Clostridium botulinum E3 str. Alaska E43 glyoxalase family protein YP_001921827.1 2621372 R 508767 CDS YP_001921828.1 188589136 6317255 complement(2621831..2622340) 1 NC_010723.1 identified by match to protein family HMM PF08020; hypothetical protein 2622340 6317255 CLH_2447 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921828.1 2621831 R 508767 CDS YP_001921829.1 188588806 6318158 complement(2622411..2622902) 1 NC_010723.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 2622902 6318158 CLH_2448 Clostridium botulinum E3 str. Alaska E43 MutT/nudix family protein YP_001921829.1 2622411 R 508767 CDS YP_001921830.1 188589690 6318389 complement(2622960..2623220) 1 NC_010723.1 identified by match to protein family HMM PF04994; TfoX C- domain superfamily 2623220 6318389 CLH_2449 Clostridium botulinum E3 str. Alaska E43 TfoX C- domain superfamily YP_001921830.1 2622960 R 508767 CDS YP_001921831.1 188590477 6320073 complement(2623465..2624121) 1 NC_010723.1 identified by match to protein family HMM PF00023; hypothetical protein 2624121 6320073 CLH_2450 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921831.1 2623465 R 508767 CDS YP_001921832.1 188587920 6319703 complement(2624165..2625007) 1 NC_010723.1 protein YieJ 2625007 6319703 CLH_2451 Clostridium botulinum E3 str. Alaska E43 protein YieJ YP_001921832.1 2624165 R 508767 CDS YP_001921833.1 188589016 6320155 complement(2625032..2625385) 1 NC_010723.1 hypothetical protein 2625385 6320155 CLH_2452 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921833.1 2625032 R 508767 CDS YP_001921834.1 188589750 6319005 complement(2625418..2625666) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2625666 6319005 CLH_2453 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921834.1 2625418 R 508767 CDS YP_001921835.1 188587664 6319489 complement(2625701..2626327) 1 NC_010723.1 identified by match to protein family HMM PF08887; match to protein family HMM PF08906; hypothetical protein 2626327 6319489 CLH_2454 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921835.1 2625701 R 508767 CDS YP_001921836.1 188588382 6320130 complement(2626822..2627640) 1 NC_010723.1 identified by match to protein family HMM TIGR01784; hypothetical protein 2627640 6320130 CLH_2455 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921836.1 2626822 R 508767 CDS YP_001921837.1 188587748 6319941 complement(2627734..2628246) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2628246 6319941 CLH_2456 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921837.1 2627734 R 508767 CDS YP_001921838.1 188588861 6318954 complement(2628466..2629128) 1 NC_010723.1 BtrU protein 2629128 6318954 CLH_2457 Clostridium botulinum E3 str. Alaska E43 BtrU protein YP_001921838.1 2628466 R 508767 CDS YP_001921839.1 188587955 6320062 complement(2629303..2629743) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2629743 6320062 CLH_2458 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921839.1 2629303 R 508767 CDS YP_001921840.1 188590789 6317271 2629895..2630530 1 NC_010723.1 identified by match to protein family HMM PF09335; hypothetical protein 2630530 6317271 CLH_2459 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921840.1 2629895 D 508767 CDS YP_001921841.1 188590027 6318162 complement(2630592..2631887) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 2631887 6318162 CLH_2460 Clostridium botulinum E3 str. Alaska E43 histidine kinase YP_001921841.1 2630592 R 508767 CDS YP_001921842.1 188589302 6319189 complement(2631884..2632570) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; regulatory protein VanR 2632570 6319189 CLH_2461 Clostridium botulinum E3 str. Alaska E43 regulatory protein VanR YP_001921842.1 2631884 R 508767 CDS YP_001921843.1 188590324 6319927 complement(2632584..2633144) 1 NC_010723.1 ribosomal RNA adenine dimethylase 2633144 6319927 CLH_2462 Clostridium botulinum E3 str. Alaska E43 ribosomal RNA adenine dimethylase YP_001921843.1 2632584 R 508767 CDS YP_001921844.1 188589339 6318936 complement(2633908..2634708) 1 NC_010723.1 hypothetical protein 2634708 6318936 CLH_2463 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921844.1 2633908 R 508767 CDS YP_001921845.1 188588863 6317815 complement(2634725..2635720) 1 NC_010723.1 hypothetical protein 2635720 6317815 CLH_2464 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921845.1 2634725 R 508767 CDS YP_001921846.1 188587936 6320589 complement(2635704..2636219) 1 NC_010723.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; sigma-70 family RNA polymerase sigma factor 2636219 6320589 CLH_2465 Clostridium botulinum E3 str. Alaska E43 sigma-70 family RNA polymerase sigma factor YP_001921846.1 2635704 R 508767 CDS YP_001921847.1 188590719 6320597 complement(2636372..2636488) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2636488 6320597 CLH_2466 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921847.1 2636372 R 508767 CDS YP_001921848.1 188589563 6320201 complement(2636534..2637661) 1 NC_010723.1 identified by match to protein family HMM PF00724; FAD/FMN-binding oxidoreductase 2637661 6320201 CLH_2467 Clostridium botulinum E3 str. Alaska E43 FAD/FMN-binding oxidoreductase YP_001921848.1 2636534 R 508767 CDS YP_001921849.1 188590605 6317476 2637851..2638189 1 NC_010723.1 identified by match to protein family HMM PF01638; HxlR family transcriptional regulator 2638189 6317476 CLH_2468 Clostridium botulinum E3 str. Alaska E43 HxlR family transcriptional regulator YP_001921849.1 2637851 D 508767 CDS YP_001921850.1 188589614 6318496 complement(2638461..2639084) 1 NC_010723.1 identified by match to protein family HMM PF00302; chloramphenicol O-acetyltransferase 2639084 6318496 CLH_2469 Clostridium botulinum E3 str. Alaska E43 chloramphenicol O-acetyltransferase YP_001921850.1 2638461 R 508767 CDS YP_001921851.1 188589087 6317885 complement(2639385..2641292) 1 NC_010723.1 putative orphan protein 2641292 6317885 CLH_2470 Clostridium botulinum E3 str. Alaska E43 putative orphan protein YP_001921851.1 2639385 R 508767 CDS YP_001921852.1 188588179 6319153 complement(2641551..2642336) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2642336 6319153 CLH_2471 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921852.1 2641551 R 508767 CDS YP_001921853.1 188589140 6319357 complement(2642583..2643167) 1 NC_010723.1 hypothetical protein 2643167 6319357 CLH_2472 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921853.1 2642583 R 508767 CDS YP_001921854.1 188588220 6318628 complement(2643145..2644017) 1 NC_010723.1 hypothetical protein 2644017 6318628 CLH_2473 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921854.1 2643145 R 508767 CDS YP_001921855.1 188590182 6319679 complement(2644196..2644411) 1 NC_010723.1 hypothetical protein 2644411 6319679 CLH_2474 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921855.1 2644196 R 508767 CDS YP_001921856.1 188589498 6320257 complement(2644463..2644825) 1 NC_010723.1 cassette chromosome recombinase B 2644825 6320257 CLH_2475 Clostridium botulinum E3 str. Alaska E43 cassette chromosome recombinase B YP_001921856.1 2644463 R 508767 CDS YP_001921857.1 188588738 6319393 complement(2645054..2645770) 1 NC_010723.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; site-specific DNA recombinase 2645770 6319393 CLH_2476 Clostridium botulinum E3 str. Alaska E43 site-specific DNA recombinase YP_001921857.1 2645054 R 508767 CDS YP_001921858.1 188588012 6317436 complement(2646065..2646502) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2646502 6317436 CLH_2477 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921858.1 2646065 R 508767 CDS YP_001921859.1 188590758 6317933 complement(2646518..2646727) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2646727 6317933 CLH_2478 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921859.1 2646518 R 508767 CDS YP_001921860.1 188588437 6318177 complement(2646788..2647072) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2647072 6318177 CLH_2479 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921860.1 2646788 R 508767 CDS YP_001921861.1 188588899 6319936 complement(2647338..2647889) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2647889 6319936 CLH_2480 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921861.1 2647338 R 508767 CDS YP_001921862.1 188589846 6317499 complement(2648233..2648382) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2648382 6317499 CLH_2481 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921862.1 2648233 R 508767 CDS YP_001921863.1 188587908 6319237 complement(2648384..2648692) 1 NC_010723.1 hypothetical protein 2648692 6319237 CLH_2482 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921863.1 2648384 R 508767 CDS YP_001921864.1 188588818 6317390 complement(2648830..2649450) 1 NC_010723.1 hypothetical protein 2649450 6317390 CLH_2483 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921864.1 2648830 R 508767 CDS YP_001921865.1 188589362 6317977 complement(2649467..2649760) 1 NC_010723.1 hypothetical protein 2649760 6317977 CLH_2484 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921865.1 2649467 R 508767 CDS YP_001921866.1 188590208 6318104 complement(2649772..2650110) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2650110 6318104 CLH_2485 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921866.1 2649772 R 508767 CDS YP_001921867.1 188588305 6317369 complement(2650177..2650485) 1 NC_010723.1 hypothetical protein 2650485 6317369 CLH_2486 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921867.1 2650177 R 508767 CDS YP_001921868.1 188588765 6320011 complement(2650555..2651469) 1 NC_010723.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; DNA-cytosine methyltransferase 2651469 dcm 6320011 dcm Clostridium botulinum E3 str. Alaska E43 DNA-cytosine methyltransferase YP_001921868.1 2650555 R 508767 CDS YP_001921869.1 188589605 6318392 complement(2651491..2652540) 1 NC_010723.1 identified by match to protein family HMM PF09519; type II restriction enzyme HgiDI 2652540 6318392 CLH_2488 Clostridium botulinum E3 str. Alaska E43 type II restriction enzyme HgiDI YP_001921869.1 2651491 R 508767 CDS YP_001921870.1 188589489 6319000 complement(2652810..2653541) 1 NC_010723.1 identified by match to protein family HMM PF09234; hypothetical protein 2653541 6319000 CLH_2489 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921870.1 2652810 R 508767 CDS YP_001921871.1 188588208 6317841 complement(2653679..2654572) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2654572 6317841 CLH_2490 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921871.1 2653679 R 508767 CDS YP_001921872.1 188588885 6319682 complement(2654846..2655256) 1 NC_010723.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 2655256 6319682 CLH_2491 Clostridium botulinum E3 str. Alaska E43 peptide deformylase YP_001921872.1 2654846 R 508767 CDS YP_001921873.1 188589258 6318859 complement(2655260..2655619) 1 NC_010723.1 identified by match to protein family HMM PF06304; hypothetical protein 2655619 6318859 CLH_2492 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921873.1 2655260 R 508767 CDS YP_001921874.1 188590792 6318021 complement(2655603..2655992) 1 NC_010723.1 identified by match to protein family HMM PF06304; putative cytoplasmic protein 2655992 6318021 CLH_2493 Clostridium botulinum E3 str. Alaska E43 putative cytoplasmic protein YP_001921874.1 2655603 R 508767 CDS YP_001921875.1 188587551 6319292 complement(2655985..2656317) 1 NC_010723.1 identified by match to protein family HMM PF03551; transcriptional regulator, PadR family 2656317 6319292 CLH_2494 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, PadR family YP_001921875.1 2655985 R 508767 CDS YP_001921876.1 188588548 6318713 complement(2656629..2657165) 1 NC_010723.1 hypothetical protein 2657165 6318713 CLH_2495 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921876.1 2656629 R 508767 CDS YP_001921877.1 188588650 6318325 complement(2657609..2657911) 1 NC_010723.1 hypothetical protein 2657911 6318325 CLH_2496 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921877.1 2657609 R 508767 CDS YP_001921878.1 188590029 6317588 2658238..2658894 1 NC_010723.1 identified by match to protein family HMM PF07007; putative lipoprotein 2658894 6317588 CLH_2497 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921878.1 2658238 D 508767 CDS YP_001921879.1 188590092 6318872 complement(2659081..2659293) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2659293 6318872 CLH_2498 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921879.1 2659081 R 508767 CDS YP_001921880.1 188587951 6317754 complement(2659397..2660194) 1 NC_010723.1 putative lipoprotein 2660194 6317754 CLH_2499 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921880.1 2659397 R 508767 CDS YP_001921881.1 188588655 6317341 complement(2660409..2660657) 1 NC_010723.1 hypothetical protein 2660657 6317341 CLH_2500 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921881.1 2660409 R 508767 CDS YP_001921882.1 188589790 6319982 complement(2660706..2661524) 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase domain-containing protein 2661524 6319982 CLH_2501 Clostridium botulinum E3 str. Alaska E43 metallo-beta-lactamase domain-containing protein YP_001921882.1 2660706 R 508767 CDS YP_001921883.1 188589770 6318359 complement(2661811..2662896) 1 NC_010723.1 identified by match to protein family HMM PF00144; beta-lactamase 2662896 6318359 CLH_2502 Clostridium botulinum E3 str. Alaska E43 beta-lactamase YP_001921883.1 2661811 R 508767 CDS YP_001921884.1 188590489 6319731 complement(2662998..2663636) 1 NC_010723.1 identified by match to protein family HMM PF00583; acetyltransferase 2663636 6319731 CLH_2503 Clostridium botulinum E3 str. Alaska E43 acetyltransferase YP_001921884.1 2662998 R 508767 CDS YP_001921885.1 188588552 6318827 complement(2663732..2664526) 1 NC_010723.1 identified by match to protein family HMM PF02274; amidinotransferase family protein 2664526 6318827 CLH_2504 Clostridium botulinum E3 str. Alaska E43 amidinotransferase family protein YP_001921885.1 2663732 R 508767 CDS YP_001921886.1 188589010 6318346 complement(2664700..2665956) 1 NC_010723.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01446; match to protein family HMM TIGR01714; putative phage replisome organizer 2665956 6318346 CLH_2505 Clostridium botulinum E3 str. Alaska E43 putative phage replisome organizer YP_001921886.1 2664700 R 508767 CDS YP_001921887.1 188589251 6319465 complement(2666314..2667126) 1 NC_010723.1 identified by match to protein family HMM PF02498; match to protein family HMM PF03374; antirepressor, phage associated 2667126 6319465 CLH_2506 Clostridium botulinum E3 str. Alaska E43 antirepressor, phage associated YP_001921887.1 2666314 R 508767 CDS YP_001921888.1 188588156 6317307 complement(2667159..2667365) 1 NC_010723.1 hypothetical protein 2667365 6317307 CLH_2507 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921888.1 2667159 R 508767 CDS YP_001921889.1 188589861 6318397 2667526..2668008 1 NC_010723.1 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 2668008 6318397 CLH_2508 Clostridium botulinum E3 str. Alaska E43 Cro/CI family transcriptional regulator YP_001921889.1 2667526 D 508767 CDS YP_001921890.1 188590446 6317938 2668207..2668689 1 NC_010723.1 identified by match to protein family HMM PF06114; hypothetical protein 2668689 6317938 CLH_2509 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921890.1 2668207 D 508767 CDS YP_001921891.1 188588056 6317809 complement(2668833..2669504) 1 NC_010723.1 identified by match to protein family HMM PF02915; match to protein family HMM PF05067; CotJC protein 2669504 6317809 CLH_2510 Clostridium botulinum E3 str. Alaska E43 CotJC protein YP_001921891.1 2668833 R 508767 CDS YP_001921892.1 188587825 6319115 2669702..2670019 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2670019 6319115 CLH_2512 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921892.1 2669702 D 508767 CDS YP_001921893.1 188587758 6319185 complement(2670013..2670126) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2670126 6319185 CLH_2511 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921893.1 2670013 R 508767 CDS YP_001921894.1 188589759 6319255 complement(2670477..2671208) 1 NC_010723.1 identified by match to protein family HMM PF01473; 1,4-beta-N-acetylmuramidase 2671208 6319255 CLH_2513 Clostridium botulinum E3 str. Alaska E43 1,4-beta-N-acetylmuramidase YP_001921894.1 2670477 R 508767 CDS YP_001921895.1 188590466 6318569 complement(2671488..2672510) 1 NC_010723.1 putative lipoprotein 2672510 6318569 CLH_2514 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921895.1 2671488 R 508767 CDS YP_001921896.1 188588303 6320373 complement(2672794..2672913) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2672913 6320373 CLH_2515 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921896.1 2672794 R 508767 CDS YP_001921897.1 188588308 6319933 complement(2673541..2674587) 1 NC_010723.1 hypothetical protein 2674587 6319933 CLH_2516 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921897.1 2673541 R 508767 CDS YP_001921898.1 188589911 6320003 complement(2674836..2675390) 1 NC_010723.1 identified by match to protein family HMM PF04471; putative restriction endonuclase 2675390 6320003 CLH_2517 Clostridium botulinum E3 str. Alaska E43 putative restriction endonuclase YP_001921898.1 2674836 R 508767 CDS YP_001921899.1 188587810 6319576 complement(2675623..2675787) 1 NC_010723.1 hypothetical protein 2675787 6319576 CLH_2518 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921899.1 2675623 R 508767 CDS YP_001921900.1 188590137 6319511 complement(2675790..2676023) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2676023 6319511 CLH_2519 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921900.1 2675790 R 508767 CDS YP_001921901.1 188589632 6318846 complement(2676001..2676510) 1 NC_010723.1 hypothetical protein 2676510 6318846 CLH_2520 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921901.1 2676001 R 508767 CDS YP_001921902.1 188590579 6320108 complement(2676500..2676721) 1 NC_010723.1 hypothetical protein 2676721 6320108 CLH_2521 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921902.1 2676500 R 508767 CDS YP_001921903.1 188587778 6318111 complement(2676910..2677911) 1 NC_010723.1 hypothetical protein 2677911 6318111 CLH_2522 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921903.1 2676910 R 508767 CDS YP_001921904.1 188587998 6319477 complement(2677937..2678626) 1 NC_010723.1 hypothetical protein 2678626 6319477 CLH_2523 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921904.1 2677937 R 508767 CDS YP_001921905.1 188588189 6320044 complement(2679402..2679596) 1 NC_010723.1 hypothetical protein 2679596 6320044 CLH_2525 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921905.1 2679402 R 508767 CDS YP_001921906.1 188590614 6319133 2679700..2679909 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2679909 6319133 CLH_2526 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921906.1 2679700 D 508767 CDS YP_001921907.1 188588410 6320236 2680068..2680838 1 NC_010723.1 hypothetical protein 2680838 6320236 CLH_2527 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921907.1 2680068 D 508767 CDS YP_001921908.1 188589482 6320008 complement(2680871..2681455) 1 NC_010723.1 putative lipoprotein 2681455 6320008 CLH_2528 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921908.1 2680871 R 508767 CDS YP_001921909.1 188590741 6319227 complement(2681506..2681757) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2681757 6319227 CLH_2529 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921909.1 2681506 R 508767 CDS YP_001921910.1 188587974 6317965 2682087..2682314 1 NC_010723.1 hypothetical protein 2682314 6317965 CLH_2530 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921910.1 2682087 D 508767 CDS YP_001921911.1 188587623 6317549 2682414..2682632 1 NC_010723.1 hypothetical protein 2682632 6317549 CLH_2531 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921911.1 2682414 D 508767 CDS YP_001921912.1 188588543 6319908 complement(2682876..2683361) 1 NC_010723.1 putative lipoprotein 2683361 6319908 CLH_2532 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921912.1 2682876 R 508767 CDS YP_001921913.1 188589426 6319143 complement(2683348..2684019) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2684019 6319143 CLH_2533 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921913.1 2683348 R 508767 CDS YP_001921914.1 188590337 6317611 complement(2684419..2685927) 1 NC_010723.1 identified by match to protein family HMM PF08903; hypothetical protein 2685927 6317611 CLH_2534 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921914.1 2684419 R 508767 CDS YP_001921915.1 188588290 6317988 complement(2686420..2686929) 1 NC_010723.1 phosphoesterase 2686929 6317988 CLH_2535 Clostridium botulinum E3 str. Alaska E43 phosphoesterase YP_001921915.1 2686420 R 508767 CDS YP_001921916.1 188589017 6319784 complement(2687141..2688442) 1 NC_010723.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF02683; match to protein family HMM PF08534; cytochrome C biogenesis protein transmembrane region family 2688442 6319784 CLH_2536 Clostridium botulinum E3 str. Alaska E43 cytochrome C biogenesis protein transmembrane region family YP_001921916.1 2687141 R 508767 CDS YP_001921917.1 188588569 6319178 complement(2688444..2688761) 1 NC_010723.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2688761 trx 6319178 trx Clostridium botulinum E3 str. Alaska E43 thioredoxin YP_001921917.1 2688444 R 508767 CDS YP_001921918.1 188589653 6319146 2689057..2690865 1 NC_010723.1 identified by match to protein family HMM PF01289; tetanolysin O 2690865 6319146 CLH_2538 Clostridium botulinum E3 str. Alaska E43 tetanolysin O YP_001921918.1 2689057 D 508767 CDS YP_001921919.1 188588740 6320112 complement(2691057..2691713) 1 NC_010723.1 identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin 2691713 6320112 CLH_2539 Clostridium botulinum E3 str. Alaska E43 4Fe-4S ferredoxin YP_001921919.1 2691057 R 508767 CDS YP_001921920.1 188587820 6317438 complement(2691887..2692489) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2692489 6317438 CLH_2540 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921920.1 2691887 R 508767 CDS YP_001921921.1 188590151 6318856 complement(2692507..2692926) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2692926 6318856 CLH_2541 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921921.1 2692507 R 508767 CDS YP_001921922.1 188588183 6317761 complement(2692929..2693045) 1 NC_010723.1 hypothetical protein 2693045 6317761 CLH_2542 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921922.1 2692929 R 508767 CDS YP_001921923.1 188589138 6319324 complement(2693063..2693713) 1 NC_010723.1 identified by match to protein family HMM PF00023; hypothetical protein 2693713 6319324 CLH_2543 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921923.1 2693063 R 508767 CDS YP_001921924.1 188588278 6318626 complement(2693784..2694347) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2694347 6318626 CLH_2544 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921924.1 2693784 R 508767 CDS YP_001921925.1 188587705 6319812 complement(2694484..2695065) 1 NC_010723.1 hypothetical protein 2695065 6319812 CLH_2545 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921925.1 2694484 R 508767 CDS YP_001921926.1 188590629 6320585 complement(2695062..2695766) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2695766 6320585 CLH_2546 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921926.1 2695062 R 508767 CDS YP_001921927.1 188589729 6319248 complement(2696180..2697199) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2697199 6319248 CLH_2547 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921927.1 2696180 R 508767 CDS YP_001921928.1 188587967 6318587 complement(2697377..2697541) 1 NC_010723.1 identified by match to protein family HMM PF09388; Spo0E like sporulation regulatory protein 2697541 6318587 CLH_2548 Clostridium botulinum E3 str. Alaska E43 Spo0E like sporulation regulatory protein YP_001921928.1 2697377 R 508767 CDS YP_001921929.1 188588866 6317661 complement(2697660..2698469) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2698469 6317661 CLH_2549 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921929.1 2697660 R 508767 CDS YP_001921930.1 188588527 6320580 complement(2698614..2699117) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2699117 6320580 CLH_2550 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001921930.1 2698614 R 508767 CDS YP_001921931.1 188589445 6318933 complement(2699221..2699448) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2699448 6318933 CLH_2551 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921931.1 2699221 R 508767 CDS YP_001921932.1 188590720 6318761 2699935..2700411 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2700411 6318761 CLH_2552 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921932.1 2699935 D 508767 CDS YP_001921933.1 188587546 6320294 complement(2700513..2701427) 1 NC_010723.1 identified by match to protein family HMM PF00892; membrane protein 2701427 6320294 CLH_2553 Clostridium botulinum E3 str. Alaska E43 membrane protein YP_001921933.1 2700513 R 508767 CDS YP_001921934.1 188589080 6319079 complement(2702131..2702661) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2702661 6319079 CLH_2554 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921934.1 2702131 R 508767 CDS YP_001921935.1 188589765 6318462 2703014..2703553 1 NC_010723.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 2703553 lepB 6318462 lepB Clostridium botulinum E3 str. Alaska E43 signal peptidase I YP_001921935.1 2703014 D 508767 CDS YP_001921936.1 188590345 6320085 complement(2703774..2705510) 1 NC_010723.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 2705510 6320085 CLH_2556 Clostridium botulinum E3 str. Alaska E43 myosin-cross-reactive antigen YP_001921936.1 2703774 R 508767 CDS YP_001921937.1 188590457 6317464 complement(2705838..2706056) 1 NC_010723.1 DEAD/DEAH box helicase 2706056 6317464 CLH_2557 Clostridium botulinum E3 str. Alaska E43 DEAD/DEAH box helicase YP_001921937.1 2705838 R 508767 CDS YP_001921938.1 188590406 6317948 2706278..2707309 1 NC_010723.1 hypothetical protein 2707309 6317948 CLH_2558 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921938.1 2706278 D 508767 CDS YP_001921939.1 188589255 6317607 complement(2707471..2708742) 1 NC_010723.1 identified by match to protein family HMM PF02687; ABC-type transport system, involved in lipoprotein release, permease component 2708742 6317607 CLH_2559 Clostridium botulinum E3 str. Alaska E43 ABC-type transport system, involved in lipoprotein release, permease component YP_001921939.1 2707471 R 508767 CDS YP_001921940.1 188588450 6318586 complement(2708733..2709470) 1 NC_010723.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 2 2709470 6318586 CLH_2560 Clostridium botulinum E3 str. Alaska E43 macrolide export ATP-binding/permease protein MacB 2 YP_001921940.1 2708733 R 508767 CDS YP_001921941.1 188589008 6319634 complement(2709460..2710908) 1 NC_010723.1 identified by match to protein family HMM PF00529; putative HylD family protein 2710908 6319634 CLH_2561 Clostridium botulinum E3 str. Alaska E43 putative HylD family protein YP_001921941.1 2709460 R 508767 CDS YP_001921942.1 188590769 6319902 complement(2710927..2712048) 1 NC_010723.1 putative viral A-type inclusion protein 2712048 6319902 CLH_2562 Clostridium botulinum E3 str. Alaska E43 putative viral A-type inclusion protein YP_001921942.1 2710927 R 508767 CDS YP_001921943.1 188589652 6320069 complement(2712401..2712916) 1 NC_010723.1 identified by match to protein family HMM PF02632; BioY protein 2712916 6320069 CLH_2563 Clostridium botulinum E3 str. Alaska E43 BioY protein YP_001921943.1 2712401 R 508767 CDS YP_001921944.1 188588690 6320497 complement(2713389..2713931) 1 NC_010723.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubredoxin/rubrerythrin 2713931 6320497 CLH_2564 Clostridium botulinum E3 str. Alaska E43 rubredoxin/rubrerythrin YP_001921944.1 2713389 R 508767 CDS YP_001921945.1 188587772 6318131 complement(2714450..2714992) 1 NC_010723.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubredoxin/rubrerythrin 2714992 6318131 CLH_2565 Clostridium botulinum E3 str. Alaska E43 rubredoxin/rubrerythrin YP_001921945.1 2714450 R 508767 CDS YP_001921946.1 188587787 6319994 2715473..2716366 1 NC_010723.1 hypothetical protein 2716366 6319994 CLH_2566 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921946.1 2715473 D 508767 CDS YP_001921947.1 188590560 6318212 complement(2716621..2718645) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 2718645 6318212 CLH_2567 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001921947.1 2716621 R 508767 CDS YP_001921948.1 188590264 6318785 complement(2719114..2719236) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2719236 6318785 CLH_2568 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921948.1 2719114 R 508767 CDS YP_001921949.1 188589332 6317439 complement(2719229..2720248) 1 NC_010723.1 identified by match to protein family HMM PF00224; pyruvate kinase, barrel domain 2720248 6317439 CLH_2569 Clostridium botulinum E3 str. Alaska E43 pyruvate kinase, barrel domain YP_001921949.1 2719229 R 508767 CDS YP_001921950.1 188589106 6318978 2720585..2721070 1 NC_010723.1 putative lipoprotein 2721070 6318978 CLH_2570 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001921950.1 2720585 D 508767 CDS YP_001921951.1 188588182 6320418 2721397..2722230 1 NC_010723.1 identified by match to protein family HMM PF02811; PHP domain-containing protein 2722230 6320418 CLH_2571 Clostridium botulinum E3 str. Alaska E43 PHP domain-containing protein YP_001921951.1 2721397 D 508767 CDS YP_001921952.1 188588210 6319323 complement(2722389..2722640) 1 NC_010723.1 hypothetical protein 2722640 6319323 CLH_2572 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921952.1 2722389 R 508767 CDS YP_001921953.1 188590586 6319684 complement(2722869..2724260) 1 NC_010723.1 catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 2724260 6319684 CLH_2573 Clostridium botulinum E3 str. Alaska E43 putative aminopeptidase YP_001921953.1 2722869 R 508767 CDS YP_001921954.1 188589663 6320218 complement(2724437..2725351) 1 NC_010723.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 2725351 hprK 6320218 hprK Clostridium botulinum E3 str. Alaska E43 HPr kinase/phosphorylase YP_001921954.1 2724437 R 508767 CDS YP_001921955.1 188587926 6320119 complement(2725368..2725556) 1 NC_010723.1 identified by match to protein family HMM PF05979; hypothetical protein 2725556 6320119 CLH_2575 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921955.1 2725368 R 508767 CDS YP_001921956.1 188587716 6318686 2725989..2726204 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2726204 6318686 CLH_2576 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921956.1 2725989 D 508767 CDS YP_001921957.1 188590230 6317239 complement(2727017..2727415) 1 NC_010723.1 hypothetical protein 2727415 6317239 CLH_2577 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921957.1 2727017 R 508767 CDS YP_001921958.1 188589462 6318255 complement(2727429..2727680) 1 NC_010723.1 identified by match to protein family HMM PF06949; hypothetical protein 2727680 6318255 CLH_2578 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921958.1 2727429 R 508767 CDS YP_001921959.1 188588883 6317323 complement(2727780..2730065) 1 NC_010723.1 identified by match to protein family HMM PF00580; ATP-dependent DNA helicase, UvrD/REP family 2730065 6317323 CLH_2579 Clostridium botulinum E3 str. Alaska E43 ATP-dependent DNA helicase, UvrD/REP family YP_001921959.1 2727780 R 508767 CDS YP_001921960.1 188587638 6319010 complement(2730579..2731124) 1 NC_010723.1 hypothetical protein 2731124 6319010 CLH_2580 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921960.1 2730579 R 508767 CDS YP_001921961.1 188590386 6320018 complement(2731610..2734021) 1 NC_010723.1 identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607; 5-methyltetrahydrofolate--homocysteine methyltransferase 2734021 6320018 CLH_2581 Clostridium botulinum E3 str. Alaska E43 5-methyltetrahydrofolate--homocysteine methyltransferase YP_001921961.1 2731610 R 508767 CDS YP_001921962.1 188590677 6319205 complement(2734011..2734697) 1 NC_010723.1 identified by match to protein family HMM PF02965; vitamin B12 dependent methionine synthase, activation domain-containing protein 2734697 6319205 CLH_2582 Clostridium botulinum E3 str. Alaska E43 vitamin B12 dependent methionine synthase, activation domain-containing protein YP_001921962.1 2734011 R 508767 CDS YP_001921963.1 188588542 6320248 complement(2734699..2735154) 1 NC_010723.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2735154 luxS 6320248 luxS Clostridium botulinum E3 str. Alaska E43 S-ribosylhomocysteinase YP_001921963.1 2734699 R 508767 CDS YP_001921964.1 188588822 6319142 complement(2735196..2736074) 1 NC_010723.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase 2736074 metF 6319142 metF Clostridium botulinum E3 str. Alaska E43 5,10-methylenetetrahydrofolate reductase YP_001921964.1 2735196 R 508767 CDS YP_001921965.1 188588309 6318176 complement(2736344..2737294) 1 NC_010723.1 identified by match to protein family HMM PF00953; UDP-GlcNAc:undecaprenyl-P GlcNAc 1-P transferase 2737294 tagO 6318176 tagO Clostridium botulinum E3 str. Alaska E43 UDP-GlcNAc:undecaprenyl-P GlcNAc 1-P transferase YP_001921965.1 2736344 R 508767 CDS YP_001921966.1 188588424 6319996 complement(2737652..2739400) 1 NC_010723.1 identified by match to protein family HMM PF00149; match to protein family HMM PF01476; match to protein family HMM PF02872; nucleotidase 2739400 6319996 CLH_2586 Clostridium botulinum E3 str. Alaska E43 nucleotidase YP_001921966.1 2737652 R 508767 CDS YP_001921967.1 188587911 6320016 complement(2739747..2740388) 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit D 2740388 6320016 CLH_2587 Clostridium botulinum E3 str. Alaska E43 V-type ATP synthase subunit D YP_001921967.1 2739747 R 508767 CDS YP_001921968.1 188588615 6317424 complement(2740392..2741771) 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit B 2741771 6317424 CLH_2588 Clostridium botulinum E3 str. Alaska E43 V-type ATP synthase subunit B YP_001921968.1 2740392 R 508767 CDS YP_001921969.1 188587942 6317670 complement(2741764..2743542) 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit A 2743542 6317670 CLH_2589 Clostridium botulinum E3 str. Alaska E43 V-type ATP synthase subunit A YP_001921969.1 2741764 R 508767 CDS YP_001921970.1 188590282 6317538 complement(2743560..2743871) 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the F subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit F 2743871 6317538 CLH_2590 Clostridium botulinum E3 str. Alaska E43 V-type ATP synthase subunit F YP_001921970.1 2743560 R 508767 CDS YP_001921971.1 188589188 6318639 complement(2743864..2744865) 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the C subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit C 2744865 6318639 CLH_2591 Clostridium botulinum E3 str. Alaska E43 V-type ATP synthase subunit C YP_001921971.1 2743864 R 508767 CDS YP_001921972.1 188589187 6317563 complement(2744878..2745468) 1 NC_010723.1 identified by match to protein family HMM PF01991; ATP synthase (E/31 kDa) subunit 2745468 6317563 CLH_2592 Clostridium botulinum E3 str. Alaska E43 ATP synthase (E/31 kDa) subunit YP_001921972.1 2744878 R 508767 CDS YP_001921973.1 188588292 6319058 complement(2745503..2745988) 1 NC_010723.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; V-type ATP synthase subunit K 2745988 6319058 CLH_2593 Clostridium botulinum E3 str. Alaska E43 V-type ATP synthase subunit K YP_001921973.1 2745503 R 508767 CDS YP_001921974.1 188590748 6319771 complement(2746002..2747936) 1 NC_010723.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel.; V-type ATP synthase subunit I 2747936 6319771 CLH_2594 Clostridium botulinum E3 str. Alaska E43 V-type ATP synthase subunit I YP_001921974.1 2746002 R 508767 CDS YP_001921975.1 188589593 6318093 complement(2747953..2748279) 1 NC_010723.1 V-type sodium ATP synthase subunit G 2748279 6318093 CLH_2595 Clostridium botulinum E3 str. Alaska E43 V-type sodium ATP synthase subunit G YP_001921975.1 2747953 R 508767 CDS YP_001921976.1 188589895 6318025 complement(2748496..2750160) 1 NC_010723.1 identified by match to protein family HMM PF02310; match to protein family HMM PF04055; radical SAM domain protein 2750160 6318025 CLH_2596 Clostridium botulinum E3 str. Alaska E43 radical SAM domain protein YP_001921976.1 2748496 R 508767 CDS YP_001921977.1 188590583 6318861 complement(2750135..2750698) 1 NC_010723.1 hypothetical protein 2750698 6318861 CLH_2597 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921977.1 2750135 R 508767 CDS YP_001921978.1 188589291 6319384 complement(2750889..2752190) 1 NC_010723.1 hypothetical protein 2752190 6319384 CLH_2598 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921978.1 2750889 R 508767 CDS YP_001921979.1 188590008 6320411 2752387..2753886 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM TIGR02900; stage V sporulation protein B 2753886 spoVB 6320411 spoVB Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein B YP_001921979.1 2752387 D 508767 CDS YP_001921980.1 188589084 6317524 complement(2754109..2755716) 1 NC_010723.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023; stage V sporulation protein B 2755716 6317524 CLH_2600 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein B YP_001921980.1 2754109 R 508767 CDS YP_001921981.1 188589626 6320415 complement(2755726..2756694) 1 NC_010723.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; RluA family pseudouridine synthase 2756694 6320415 CLH_2601 Clostridium botulinum E3 str. Alaska E43 RluA family pseudouridine synthase YP_001921981.1 2755726 R 508767 CDS YP_001921982.1 188590567 6318555 complement(2756727..2757908) 1 NC_010723.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; thermostable carboxypeptidase 1 2757908 6318555 CLH_2602 Clostridium botulinum E3 str. Alaska E43 thermostable carboxypeptidase 1 YP_001921982.1 2756727 R 508767 CDS YP_001921983.1 188587806 6320228 complement(2757935..2760070) 1 NC_010723.1 cell division protein FtsA 2760070 6320228 CLH_2603 Clostridium botulinum E3 str. Alaska E43 cell division protein FtsA YP_001921983.1 2757935 R 508767 CDS YP_001921984.1 188588702 6319774 complement(2760306..2760425) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2760425 6319774 CLH_2604 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921984.1 2760306 R 508767 CDS YP_001921985.1 188589230 6318599 complement(2760599..2762605) 1 NC_010723.1 identified by match to protein family HMM PF00580; ATP-dependent helicase 2762605 6318599 CLH_2605 Clostridium botulinum E3 str. Alaska E43 ATP-dependent helicase YP_001921985.1 2760599 R 508767 CDS YP_001921986.1 188588367 6320483 2762789..2764267 1 NC_010723.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2764267 pncB 6320483 pncB Clostridium botulinum E3 str. Alaska E43 nicotinate phosphoribosyltransferase YP_001921986.1 2762789 D 508767 CDS YP_001921987.1 188589526 6319711 complement(2764328..2764534) 1 NC_010723.1 hypothetical protein 2764534 6319711 CLH_2607 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921987.1 2764328 R 508767 CDS YP_001921988.1 188588624 6318146 complement(2764784..2765101) 1 NC_010723.1 hypothetical protein 2765101 6318146 CLH_2608 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921988.1 2764784 R 508767 CDS YP_001921989.1 188587919 6317703 complement(2765348..2765665) 1 NC_010723.1 hypothetical protein 2765665 6317703 CLH_2609 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921989.1 2765348 R 508767 CDS YP_001921990.1 188590108 6320154 2765928..2766353 1 NC_010723.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 2766353 6320154 CLH_2610 Clostridium botulinum E3 str. Alaska E43 Fur family transcriptional regulator YP_001921990.1 2765928 D 508767 CDS YP_001921991.1 188589345 6317469 2766476..2767387 1 NC_010723.1 hypothetical protein 2767387 6317469 CLH_2611 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921991.1 2766476 D 508767 CDS YP_001921992.1 188589629 6318207 complement(2767526..2768128) 1 NC_010723.1 hypothetical protein 2768128 6318207 CLH_2612 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921992.1 2767526 R 508767 CDS YP_001921993.1 188589162 6318542 complement(2768243..2768524) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2768524 6318542 CLH_2613 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921993.1 2768243 R 508767 CDS YP_001921994.1 188587764 6318563 complement(2768557..2769093) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2769093 6318563 CLH_2614 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001921994.1 2768557 R 508767 CDS YP_001921995.1 188590593 6319448 complement(2769277..2769873) 1 NC_010723.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 2769873 engB 6319448 engB Clostridium botulinum E3 str. Alaska E43 ribosome biogenesis GTP-binding protein YsxC YP_001921995.1 2769277 R 508767 CDS YP_001921996.1 188587907 6318410 complement(2769863..2772196) 1 NC_010723.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07726; match to protein family HMM PF07728; match to protein family HMM TIGR00763; ATP-dependent protease La 2772196 lon 6318410 lon Clostridium botulinum E3 str. Alaska E43 ATP-dependent protease La YP_001921996.1 2769863 R 508767 CDS YP_001921997.1 188590512 6317389 complement(2772527..2773816) 1 NC_010723.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 2773816 clpX 6317389 clpX Clostridium botulinum E3 str. Alaska E43 ATP-dependent protease ATP-binding subunit ClpX YP_001921997.1 2772527 R 508767 CDS YP_001921998.1 188590743 6319150 complement(2773856..2774455) 1 NC_010723.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2774455 clpP 6319150 clpP Clostridium botulinum E3 str. Alaska E43 ATP-dependent Clp protease proteolytic subunit YP_001921998.1 2773856 R 508767 CDS YP_001921999.1 188589514 6318180 complement(2774608..2775891) 1 NC_010723.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 2775891 tig 6318180 tig Clostridium botulinum E3 str. Alaska E43 trigger factor YP_001921999.1 2774608 R 508767 CDS YP_001922000.1 188588388 6317823 complement(2775984..2776775) 1 NC_010723.1 putative secreted protein 2776775 6317823 CLH_2620 Clostridium botulinum E3 str. Alaska E43 putative secreted protein YP_001922000.1 2775984 R 508767 CDS YP_001922001.1 188588838 6319977 complement(2776875..2777081) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2777081 6319977 CLH_2621 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922001.1 2776875 R 508767 CDS YP_001922002.1 188588114 6317242 2777399..2778169 1 NC_010723.1 identified by match to protein family HMM PF02811; match to protein family HMM TIGR01856; histidinol-phosphatase 2778169 6317242 CLH_2622 Clostridium botulinum E3 str. Alaska E43 histidinol-phosphatase YP_001922002.1 2777399 D 508767 CDS YP_001922003.1 188590679 6319724 complement(2778353..2778679) 1 NC_010723.1 identified by match to protein family HMM PF01503; match to protein family HMM TIGR03188; match to protein family HMM TIGR03456; phosphoribosyl-ATP diphosphatase 2778679 hisE 6319724 hisE Clostridium botulinum E3 str. Alaska E43 phosphoribosyl-ATP diphosphatase YP_001922003.1 2778353 R 508767 CDS YP_001922004.1 188589931 6318493 complement(2778701..2779030) 1 NC_010723.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 2779030 hisI 6318493 hisI Clostridium botulinum E3 str. Alaska E43 phosphoribosyl-AMP cyclohydrolase YP_001922004.1 2778701 R 508767 CDS YP_001922005.1 188588445 6319506 complement(2779148..2779909) 1 NC_010723.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2779909 hisF 6319506 hisF Clostridium botulinum E3 str. Alaska E43 imidazole glycerol phosphate synthase subunit HisF YP_001922005.1 2779148 R 508767 CDS YP_001922006.1 188587738 6319743 complement(2779947..2780660) 1 NC_010723.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2780660 hisA 6319743 hisA Clostridium botulinum E3 str. Alaska E43 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_001922006.1 2779947 R 508767 CDS YP_001922007.1 188588973 6319688 complement(2780657..2781277) 1 NC_010723.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2781277 hisH 6319688 hisH Clostridium botulinum E3 str. Alaska E43 imidazole glycerol phosphate synthase subunit HisH YP_001922007.1 2780657 R 508767 CDS YP_001922008.1 188590076 6319584 complement(2781299..2781886) 1 NC_010723.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2781886 hisB 6319584 hisB Clostridium botulinum E3 str. Alaska E43 imidazoleglycerol-phosphate dehydratase YP_001922008.1 2781299 R 508767 CDS YP_001922009.1 188588556 6317594 complement(2781876..2782928) 1 NC_010723.1 identified by match to protein family HMM PF00155; histidinol-phosphate aminotransferase 2782928 6317594 CLH_2629 Clostridium botulinum E3 str. Alaska E43 histidinol-phosphate aminotransferase YP_001922009.1 2781876 R 508767 CDS YP_001922010.1 188589254 6318140 complement(2782929..2784215) 1 NC_010723.1 identified by match to protein family HMM PF00815; match to protein family HMM TIGR00069; histidinol dehydrogenase 2784215 hisD 6318140 hisD Clostridium botulinum E3 str. Alaska E43 histidinol dehydrogenase YP_001922010.1 2782929 R 508767 CDS YP_001922011.1 188590450 6318585 complement(2784277..2784900) 1 NC_010723.1 identified by match to protein family HMM PF01634; match to protein family HMM TIGR00070; ATP phosphoribosyltransferase 2784900 hisG 6318585 hisG Clostridium botulinum E3 str. Alaska E43 ATP phosphoribosyltransferase YP_001922011.1 2784277 R 508767 CDS YP_001922012.1 188587803 6317740 complement(2784903..2786051) 1 NC_010723.1 identified by match to protein family HMM PF00587; match to protein family HMM TIGR00443; ATP phosphoribosyltransferase, regulatory subunit 2786051 hisZ 6317740 hisZ Clostridium botulinum E3 str. Alaska E43 ATP phosphoribosyltransferase, regulatory subunit YP_001922012.1 2784903 R 508767 CDS YP_001922013.1 188589731 6320158 complement(2786413..2786919) 1 NC_010723.1 identified by match to protein family HMM PF00583; diamine acetyltransferase 1 2786919 6320158 CLH_2633 Clostridium botulinum E3 str. Alaska E43 diamine acetyltransferase 1 YP_001922013.1 2786413 R 508767 CDS YP_001922014.1 188590501 6318589 complement(2787166..2788323) 1 NC_010723.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 2788323 thiI 6318589 thiI Clostridium botulinum E3 str. Alaska E43 thiamine biosynthesis protein ThiI YP_001922014.1 2787166 R 508767 CDS YP_001922015.1 188588301 6319041 complement(2788323..2789468) 1 NC_010723.1 identified by match to protein family HMM PF00266; cysteine desulfurase 2789468 6319041 CLH_2635 Clostridium botulinum E3 str. Alaska E43 cysteine desulfurase YP_001922015.1 2788323 R 508767 CDS YP_001922016.1 188589061 6319931 complement(2789978..2790829) 1 NC_010723.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 2790829 6319931 CLH_2636 Clostridium botulinum E3 str. Alaska E43 DegV family protein YP_001922016.1 2789978 R 508767 CDS YP_001922017.1 188589761 6319904 complement(2791187..2791624) 1 NC_010723.1 identified by match to protein family HMM PF01842; hypothetical protein 2791624 6319904 CLH_2637 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922017.1 2791187 R 508767 CDS YP_001922018.1 188588222 6319131 complement(2791624..2792520) 1 NC_010723.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2792520 thrB 6319131 thrB Clostridium botulinum E3 str. Alaska E43 homoserine kinase YP_001922018.1 2791624 R 508767 CDS YP_001922019.1 188589137 6319657 complement(2792524..2793987) 1 NC_010723.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 2793987 thrC 6319657 thrC Clostridium botulinum E3 str. Alaska E43 threonine synthase YP_001922019.1 2792524 R 508767 CDS YP_001922020.1 188589641 6318159 complement(2794106..2795044) 1 NC_010723.1 hypothetical protein 2795044 6318159 CLH_2640 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922020.1 2794106 R 508767 CDS YP_001922021.1 188590612 6320456 2795316..2796299 1 NC_010723.1 lipase 2796299 6320456 CLH_2641 Clostridium botulinum E3 str. Alaska E43 lipase YP_001922021.1 2795316 D 508767 CDS YP_001922022.1 188588629 6318109 complement(2796374..2797513) 1 NC_010723.1 identified by match to protein family HMM PF07885; Ion channel family 2797513 6318109 CLH_2642 Clostridium botulinum E3 str. Alaska E43 Ion channel family YP_001922022.1 2796374 R 508767 CDS YP_001922023.1 188589535 6318927 complement(2797583..2798140) 1 NC_010723.1 hypothetical protein 2798140 6318927 CLH_2643 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922023.1 2797583 R 508767 CDS YP_001922024.1 188590160 6319239 2798332..2799102 1 NC_010723.1 identified by match to protein family HMM PF00561; lysophospholipase 2799102 6319239 CLH_2644 Clostridium botulinum E3 str. Alaska E43 lysophospholipase YP_001922024.1 2798332 D 508767 CDS YP_001922025.1 188587663 6317775 complement(2799282..2800079) 1 NC_010723.1 identified by match to protein family HMM PF06180; sirohydrochlorin cobaltochelatase 2800079 6317775 CLH_2645 Clostridium botulinum E3 str. Alaska E43 sirohydrochlorin cobaltochelatase YP_001922025.1 2799282 R 508767 CDS YP_001922026.1 188589139 6319559 complement(2800069..2801352) 1 NC_010723.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 2801352 hemL 6319559 hemL Clostridium botulinum E3 str. Alaska E43 glutamate-1-semialdehyde aminotransferase YP_001922026.1 2800069 R 508767 CDS YP_001922027.1 188589235 6318627 complement(2801404..2802369) 1 NC_010723.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2802369 hemB 6318627 hemB Clostridium botulinum E3 str. Alaska E43 delta-aminolevulinic acid dehydratase YP_001922027.1 2801404 R 508767 CDS YP_001922028.1 188590257 6317790 complement(2802372..2803847) 1 NC_010723.1 identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469; uroporphyrinogen III synthase/methyltransferase 2803847 6317790 CLH_2648 Clostridium botulinum E3 str. Alaska E43 uroporphyrinogen III synthase/methyltransferase YP_001922028.1 2802372 R 508767 CDS YP_001922029.1 188589216 6320067 complement(2804062..2804934) 1 NC_010723.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 2804934 hemC 6320067 hemC Clostridium botulinum E3 str. Alaska E43 porphobilinogen deaminase YP_001922029.1 2804062 R 508767 CDS YP_001922030.1 188589906 6317509 complement(2804986..2805660) 1 NC_010723.1 catalyzes the formation of siroheme from precorrin-2; precorrin-2 dehydrogenase 2805660 6317509 CLH_2650 Clostridium botulinum E3 str. Alaska E43 precorrin-2 dehydrogenase YP_001922030.1 2804986 R 508767 CDS YP_001922031.1 188588971 6320533 complement(2805618..2806823) 1 NC_010723.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 2806823 hemA 6320533 hemA Clostridium botulinum E3 str. Alaska E43 glutamyl-tRNA reductase YP_001922031.1 2805618 R 508767 CDS YP_001922032.1 188587996 6319660 complement(2807244..2808101) 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01077; match to protein family HMM PF03460; anaerobic sulfite reductase subunit C 2808101 6319660 CLH_2652 Clostridium botulinum E3 str. Alaska E43 anaerobic sulfite reductase subunit C YP_001922032.1 2807244 R 508767 CDS YP_001922033.1 188590328 6317533 2808459..2809100 1 NC_010723.1 identified by match to protein family HMM PF01255; undecaprenyl pyrophosphate synthetase 2809100 6317533 CLH_2653 Clostridium botulinum E3 str. Alaska E43 undecaprenyl pyrophosphate synthetase YP_001922033.1 2808459 D 508767 CDS YP_001922034.1 188589453 6318326 complement(2809878..2811230) 1 NC_010723.1 identified by match to protein family HMM PF00209; sodium transporter family protein 2811230 6318326 CLH_2654 Clostridium botulinum E3 str. Alaska E43 sodium transporter family protein YP_001922034.1 2809878 R 508767 CDS YP_001922035.1 188588554 6319060 complement(2811563..2812483) 1 NC_010723.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 2812483 metA 6319060 metA Clostridium botulinum E3 str. Alaska E43 homoserine O-succinyltransferase YP_001922035.1 2811563 R 508767 CDS YP_001922036.1 188587570 6318138 2812853..2813911 1 NC_010723.1 hypothetical protein 2813911 6318138 CLH_2656 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922036.1 2812853 D 508767 CDS YP_001922037.1 188589645 6318124 complement(2814024..2814833) 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YidA 2814833 6318124 CLH_2657 Clostridium botulinum E3 str. Alaska E43 phosphatase YidA YP_001922037.1 2814024 R 508767 CDS YP_001922038.1 188587865 6320079 2815087..2815710 1 NC_010723.1 identified by match to protein family HMM TIGR02840; putative sporulation protein YtaF 2815710 6320079 CLH_2658 Clostridium botulinum E3 str. Alaska E43 putative sporulation protein YtaF YP_001922038.1 2815087 D 508767 CDS YP_001922039.1 188590025 6317541 complement(2815892..2817397) 1 NC_010723.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 2817397 cobQ 6317541 cobQ Clostridium botulinum E3 str. Alaska E43 cobyric acid synthase YP_001922039.1 2815892 R 508767 CDS YP_001922040.1 188589317 6319187 complement(2817449..2818102) 1 NC_010723.1 identified by match to protein family HMM PF01902; match to protein family HMM TIGR00290; protein containing ATP-binding domain 2818102 6319187 CLH_2660 Clostridium botulinum E3 str. Alaska E43 protein containing ATP-binding domain YP_001922040.1 2817449 R 508767 CDS YP_001922041.1 188588562 6317626 complement(2818164..2819246) 1 NC_010723.1 cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; threonine-phosphate decarboxylase 2819246 6317626 CLH_2661 Clostridium botulinum E3 str. Alaska E43 threonine-phosphate decarboxylase YP_001922041.1 2818164 R 508767 CDS YP_001922042.1 188587852 6318200 complement(2819239..2820189) 1 NC_010723.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 2820189 cobD 6318200 cobD Clostridium botulinum E3 str. Alaska E43 cobalamin biosynthesis protein YP_001922042.1 2819239 R 508767 CDS YP_001922043.1 188589681 6317657 complement(2820308..2820916) 1 NC_010723.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 2820916 6317657 CLH_2663 Clostridium botulinum E3 str. Alaska E43 phosphoglycerate mutase family protein YP_001922043.1 2820308 R 508767 CDS YP_001922044.1 188589091 6319419 complement(2820909..2821322) 1 NC_010723.1 hypothetical protein 2821322 6319419 CLH_2664 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922044.1 2820909 R 508767 CDS YP_001922045.1 188588178 6318764 complement(2821438..2822196) 1 NC_010723.1 identified by match to protein family HMM PF02654; cobalamin-5-phosphate synthase 2822196 cobS 6318764 cobS Clostridium botulinum E3 str. Alaska E43 cobalamin-5-phosphate synthase YP_001922045.1 2821438 R 508767 CDS YP_001922046.1 188590129 6319400 complement(2822205..2822759) 1 NC_010723.1 hypothetical protein 2822759 6319400 CLH_2666 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922046.1 2822205 R 508767 CDS YP_001922047.1 188589182 6317455 complement(2822761..2823291) 1 NC_010723.1 identified by match to protein family HMM PF02572; ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 2823291 6317455 CLH_2667 Clostridium botulinum E3 str. Alaska E43 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_001922047.1 2822761 R 508767 CDS YP_001922048.1 188589170 6317415 complement(2823564..2825135) 1 NC_010723.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069; glycine betaine/carnitine/choline transport system permease protein opucb 2825135 6317415 CLH_2668 Clostridium botulinum E3 str. Alaska E43 glycine betaine/carnitine/choline transport system permease protein opucb YP_001922048.1 2823564 R 508767 CDS YP_001922049.1 188588412 6318154 complement(2825137..2826264) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186; glycine betaine/L-proline ABC transporter ATP-binding protein 2826264 6318154 CLH_2669 Clostridium botulinum E3 str. Alaska E43 glycine betaine/L-proline ABC transporter ATP-binding protein YP_001922049.1 2825137 R 508767 CDS YP_001922050.1 188589286 6319732 complement(2826367..2826996) 1 NC_010723.1 identified by match to protein family HMM PF00392; match to protein family HMM PF02080; GntR family transcriptional regulator 2826996 6319732 CLH_2670 Clostridium botulinum E3 str. Alaska E43 GntR family transcriptional regulator YP_001922050.1 2826367 R 508767 CDS YP_001922051.1 188589829 6317429 complement(2827199..2827684) 1 NC_010723.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; putative thiol peroxidase 2827684 6317429 CLH_2671 Clostridium botulinum E3 str. Alaska E43 putative thiol peroxidase YP_001922051.1 2827199 R 508767 CDS YP_001922052.1 188590726 6317315 2827848..2828180 1 NC_010723.1 hypothetical protein 2828180 6317315 CLH_2672 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922052.1 2827848 D 508767 CDS YP_001922053.1 188588901 6318799 complement(2828182..2828733) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2828733 6318799 CLH_2673 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922053.1 2828182 R 508767 CDS YP_001922054.1 188589576 6318550 complement(2828935..2830026) 1 NC_010723.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2830026 cobT 6318550 cobT Clostridium botulinum E3 str. Alaska E43 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_001922054.1 2828935 R 508767 CDS YP_001922055.1 188590645 6319781 complement(2830511..2831275) 1 NC_010723.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 2831275 cobK 6319781 cobK Clostridium botulinum E3 str. Alaska E43 cobalt-precorrin-6x reductase YP_001922055.1 2830511 R 508767 CDS YP_001922056.1 188588075 6319295 complement(2831275..2832012) 1 NC_010723.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466; precorrin-3B C(17)-methyltransferase 2832012 cobJ 6319295 cobJ Clostridium botulinum E3 str. Alaska E43 precorrin-3B C(17)-methyltransferase YP_001922056.1 2831275 R 508767 CDS YP_001922057.1 188589347 6320266 complement(2832031..2833092) 1 NC_010723.1 identified by match to protein family HMM PF01890; CbiG protein 2833092 6320266 CLH_2677 Clostridium botulinum E3 str. Alaska E43 CbiG protein YP_001922057.1 2832031 R 508767 CDS YP_001922058.1 188590497 6318533 complement(2833089..2833847) 1 NC_010723.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; precorrin-4 C(11)-methyltransferase 2833847 cobM 6318533 cobM Clostridium botulinum E3 str. Alaska E43 precorrin-4 C(11)-methyltransferase YP_001922058.1 2833089 R 508767 CDS YP_001922059.1 188590098 6319093 complement(2834035..2834697) 1 NC_010723.1 catalyzes the formation of precorrin-3A from precorrin-2; cobalt-precorrin-2 C(20)-methyltransferase 2834697 cobI 6319093 cobI Clostridium botulinum E3 str. Alaska E43 cobalt-precorrin-2 C(20)-methyltransferase YP_001922059.1 2834035 R 508767 CDS YP_001922060.1 188589381 6317325 complement(2834699..2835277) 1 NC_010723.1 identified by match to protein family HMM TIGR02469; putative cobalt-precorrin-6Y C(15)-methyltransferase 2835277 6317325 CLH_2680 Clostridium botulinum E3 str. Alaska E43 putative cobalt-precorrin-6Y C(15)-methyltransferase YP_001922060.1 2834699 R 508767 CDS YP_001922061.1 188588607 6318137 complement(2835290..2835892) 1 NC_010723.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; precorrin-6y C5,15-methyltransferase subunit CbiE 2835892 cbiE 6318137 cbiE Clostridium botulinum E3 str. Alaska E43 precorrin-6y C5,15-methyltransferase subunit CbiE YP_001922061.1 2835290 R 508767 CDS YP_001922062.1 188587891 6317346 complement(2835900..2837045) 1 NC_010723.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 2837045 cbiD 6317346 cbiD Clostridium botulinum E3 str. Alaska E43 cobalt-precorrin-6A synthase YP_001922062.1 2835900 R 508767 CDS YP_001922063.1 188587882 6317350 complement(2837193..2837816) 1 NC_010723.1 catalyzes the interconversion of precorrin-8X and cobyrinic acid; precorrin-8X methylmutase 2837816 cbiC 6317350 cbiC Clostridium botulinum E3 str. Alaska E43 precorrin-8X methylmutase YP_001922063.1 2837193 R 508767 CDS YP_001922064.1 188589624 6319814 complement(2837964..2839280) 1 NC_010723.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 2839280 cobB 6319814 cobB Clostridium botulinum E3 str. Alaska E43 cobyrinic acid a,c-diamide synthase YP_001922064.1 2837964 R 508767 CDS YP_001922065.1 188588957 6318553 complement(2839470..2840306) 1 NC_010723.1 identified by match to protein family HMM PF06180; sirohydrochlorin cobaltochelatase 2840306 6318553 CLH_2685 Clostridium botulinum E3 str. Alaska E43 sirohydrochlorin cobaltochelatase YP_001922065.1 2839470 R 508767 CDS YP_001922066.1 188588139 6319344 2841127..2841663 1 NC_010723.1 hypothetical protein 2841663 6319344 CLH_2686 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922066.1 2841127 D 508767 CDS YP_001922067.1 188588332 6318575 complement(2841746..2843059) 1 NC_010723.1 identified by match to protein family HMM PF00209; sodium:neurotransmitter symporter family protein 2843059 6318575 CLH_2687 Clostridium botulinum E3 str. Alaska E43 sodium:neurotransmitter symporter family protein YP_001922067.1 2841746 R 508767 CDS YP_001922068.1 188588872 6320029 complement(2843328..2843492) 1 NC_010723.1 hypothetical protein 2843492 6320029 CLH_2688 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922068.1 2843328 R 508767 CDS YP_001922069.1 188589385 6318998 2844145..2844261 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2844261 6318998 CLH_2690 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922069.1 2844145 D 508767 CDS YP_001922070.1 188589686 6318679 complement(2844411..2845364) 1 NC_010723.1 identified by match to protein family HMM PF00294; fructokinase 2845364 6318679 CLH_2691 Clostridium botulinum E3 str. Alaska E43 fructokinase YP_001922070.1 2844411 R 508767 CDS YP_001922071.1 188590601 6319953 complement(2845460..2845786) 1 NC_010723.1 identified by match to protein family HMM PF00903; glyoxalase/bleomycin resistance protein/dioxygenase 2845786 6319953 CLH_2692 Clostridium botulinum E3 str. Alaska E43 glyoxalase/bleomycin resistance protein/dioxygenase YP_001922071.1 2845460 R 508767 CDS YP_001922072.1 188588236 6320270 complement(2845828..2846877) 1 NC_010723.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; sorbitol dehydrogenase 2846877 6320270 CLH_2693 Clostridium botulinum E3 str. Alaska E43 sorbitol dehydrogenase YP_001922072.1 2845828 R 508767 CDS YP_001922073.1 188589888 6319594 complement(2847057..2848178) 1 NC_010723.1 identified by match to protein family HMM PF02378; phosphotransferase system, EIIC 2848178 6319594 CLH_2694 Clostridium botulinum E3 str. Alaska E43 phosphotransferase system, EIIC YP_001922073.1 2847057 R 508767 CDS YP_001922074.1 188590765 6318446 complement(2848488..2849615) 1 NC_010723.1 identified by match to protein family HMM PF00480; ROK family protein 2849615 6318446 CLH_2695 Clostridium botulinum E3 str. Alaska E43 ROK family protein YP_001922074.1 2848488 R 508767 CDS YP_001922075.1 188587677 6318519 2849886..2850377 1 NC_010723.1 identified by match to protein family HMM PF00258; flavodoxin 2850377 6318519 CLH_2696 Clostridium botulinum E3 str. Alaska E43 flavodoxin YP_001922075.1 2849886 D 508767 CDS YP_001922076.1 188588598 6318559 complement(2850512..2850979) 1 NC_010723.1 identified by match to protein family HMM PF04509; CheX protein 2850979 6318559 CLH_2697 Clostridium botulinum E3 str. Alaska E43 CheX protein YP_001922076.1 2850512 R 508767 CDS YP_001922077.1 188588609 6318841 complement(2850961..2851836) 1 NC_010723.1 identified by match to protein family HMM PF00072; putative chemotaxis sensory transduction protein 2851836 6318841 CLH_2698 Clostridium botulinum E3 str. Alaska E43 putative chemotaxis sensory transduction protein YP_001922077.1 2850961 R 508767 CDS YP_001922078.1 188587988 6320354 complement(2852014..2852154) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2852154 6320354 CLH_2699 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922078.1 2852014 R 508767 CDS YP_001922079.1 188588375 6318426 complement(2852463..2853731) 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease 2853731 6318426 CLH_2700 Clostridium botulinum E3 str. Alaska E43 uracil permease YP_001922079.1 2852463 R 508767 CDS YP_001922080.1 188587713 6320006 complement(2854151..2854933) 1 NC_010723.1 identified by match to protein family HMM PF00959; match to protein family HMM PF01473; putative phage lysozyme 2854933 6320006 CLH_2701 Clostridium botulinum E3 str. Alaska E43 putative phage lysozyme YP_001922080.1 2854151 R 508767 CDS YP_001922081.1 188590662 6317880 complement(2855206..2856069) 1 NC_010723.1 identified by match to protein family HMM PF00753; beta-lactamase 2856069 6317880 CLH_2702 Clostridium botulinum E3 str. Alaska E43 beta-lactamase YP_001922081.1 2855206 R 508767 CDS YP_001922082.1 188589969 6318456 complement(2856086..2856919) 1 NC_010723.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 2856919 6318456 CLH_2703 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001922082.1 2856086 R 508767 CDS YP_001922083.1 188588341 6319034 complement(2857305..2859140) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; lipid A export ATP-binding/permease protein MsbA 2859140 6319034 CLH_2704 Clostridium botulinum E3 str. Alaska E43 lipid A export ATP-binding/permease protein MsbA YP_001922083.1 2857305 R 508767 CDS YP_001922084.1 188590476 6318364 complement(2859133..2861364) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 2861364 6318364 CLH_2705 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding/permease YP_001922084.1 2859133 R 508767 CDS YP_001922085.1 188590235 6319702 2861649..2862104 1 NC_010723.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 2862104 6319702 CLH_2706 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, MarR family YP_001922085.1 2861649 D 508767 CDS YP_003264529.1 261876180 8538025 complement(2863032..2863994) 1 NC_010723.1 ribulokinase 2863994 8538025 CLH_2708 Clostridium botulinum E3 str. Alaska E43 ribulokinase YP_003264529.1 2863032 R 508767 CDS YP_001922086.1 188587789 6319374 complement(2864218..2866413) 1 NC_010723.1 identified by match to protein family HMM PF00465; match to protein family HMM PF00702; match to protein family HMM PF01761; match to protein family HMM TIGR01460; glycerol-1-phosphate dehydrogenase 2866413 6319374 CLH_2709 Clostridium botulinum E3 str. Alaska E43 glycerol-1-phosphate dehydrogenase YP_001922086.1 2864218 R 508767 CDS YP_001922087.1 188588436 6320577 2867065..2868165 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; putative transcriptional regulator 2868165 6320577 CLH_2710 Clostridium botulinum E3 str. Alaska E43 putative transcriptional regulator YP_001922087.1 2867065 D 508767 CDS YP_001922088.1 188587671 6319935 2868725..2869507 1 NC_010723.1 identified by match to protein family HMM PF02535; zinc transporter ZupT 2869507 6319935 CLH_2711 Clostridium botulinum E3 str. Alaska E43 zinc transporter ZupT YP_001922088.1 2868725 D 508767 CDS YP_001922089.1 188590296 6319808 complement(2869769..2870545) 1 NC_010723.1 galactose-1-phosphate uridylyltransferase 2870545 6319808 CLH_2712 Clostridium botulinum E3 str. Alaska E43 galactose-1-phosphate uridylyltransferase YP_001922089.1 2869769 R 508767 CDS YP_001922090.1 188589577 6320348 2870862..2871944 1 NC_010723.1 identified by match to protein family HMM PF06207; hypothetical protein 2871944 6320348 CLH_2713 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922090.1 2870862 D 508767 CDS YP_001922091.1 188588801 6317835 2872063..2872536 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2872536 6317835 CLH_2714 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922091.1 2872063 D 508767 CDS YP_001922092.1 188590295 6319258 complement(2872608..2873282) 1 NC_010723.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460; sulfite reductase, assimilatory-type 2873282 6319258 CLH_2715 Clostridium botulinum E3 str. Alaska E43 sulfite reductase, assimilatory-type YP_001922092.1 2872608 R 508767 CDS YP_001922093.1 188590649 6318767 complement(2873315..2873662) 1 NC_010723.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; ArsC family protein 2873662 6318767 CLH_2716 Clostridium botulinum E3 str. Alaska E43 ArsC family protein YP_001922093.1 2873315 R 508767 CDS YP_001922094.1 188589924 6317911 complement(2873886..2874431) 1 NC_010723.1 hypothetical protein 2874431 6317911 CLH_2717 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922094.1 2873886 R 508767 CDS YP_001922095.1 188589819 6318423 complement(2874806..2875696) 1 NC_010723.1 identified by match to protein family HMM PF04018; hypothetical protein 2875696 6318423 CLH_2718 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922095.1 2874806 R 508767 CDS YP_001922096.1 188589214 6319832 complement(2875978..2876136) 1 NC_010723.1 hypothetical protein 2876136 6319832 CLH_2719 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922096.1 2875978 R 508767 CDS YP_001922097.1 188589037 6317774 2876505..2877350 1 NC_010723.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 2877350 6317774 CLH_2720 Clostridium botulinum E3 str. Alaska E43 DegV family protein YP_001922097.1 2876505 D 508767 CDS YP_001922098.1 188588836 6318845 complement(2877481..2878191) 1 NC_010723.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 2878191 deoD 6318845 deoD Clostridium botulinum E3 str. Alaska E43 purine nucleoside phosphorylase YP_001922098.1 2877481 R 508767 CDS YP_001922099.1 188588721 6317240 complement(2878246..2878653) 1 NC_010723.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2878653 cdd 6317240 cdd Clostridium botulinum E3 str. Alaska E43 cytidine deaminase YP_001922099.1 2878246 R 508767 CDS YP_001922100.1 188588090 6317695 complement(2878867..2879820) 1 NC_010723.1 identified by match to protein family HMM PF02653; ABC transporter permease 2879820 6317695 CLH_2723 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001922100.1 2878867 R 508767 CDS YP_001922101.1 188590703 6320024 complement(2879822..2880976) 1 NC_010723.1 identified by match to protein family HMM PF02653; ABC transporter permease 2880976 6320024 CLH_2724 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001922101.1 2879822 R 508767 CDS YP_001922102.1 188588468 6320203 complement(2880973..2882496) 1 NC_010723.1 identified by match to protein family HMM PF00005; galactose/methyl galactoside import ATP-binding protein MglA 2882496 6320203 CLH_2725 Clostridium botulinum E3 str. Alaska E43 galactose/methyl galactoside import ATP-binding protein MglA YP_001922102.1 2880973 R 508767 CDS YP_001922103.1 188587722 6319920 complement(2882739..2883842) 1 NC_010723.1 identified by match to protein family HMM PF02608; membrane lipoprotein tmpc 2883842 6319920 CLH_2726 Clostridium botulinum E3 str. Alaska E43 membrane lipoprotein tmpc YP_001922103.1 2882739 R 508767 CDS YP_001922104.1 188590664 6318288 complement(2884015..2885034) 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator 2885034 6318288 CLH_2727 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001922104.1 2884015 R 508767 CDS YP_001922105.1 188589947 6320312 complement(2885769..2886938) 1 NC_010723.1 identified by match to protein family HMM PF00155; aspartate aminotransferase 2886938 6320312 CLH_2728 Clostridium botulinum E3 str. Alaska E43 aspartate aminotransferase YP_001922105.1 2885769 R 508767 CDS YP_001922106.1 188588604 6319751 complement(2886935..2887414) 1 NC_010723.1 identified by match to protein family HMM PF01037; transcriptional regulator, AsnC family 2887414 6319751 CLH_2729 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, AsnC family YP_001922106.1 2886935 R 508767 CDS YP_001922107.1 188587681 6317599 complement(2888167..2890122) 1 NC_010723.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; pullulanase 2890122 pulA 6317599 pulA Clostridium botulinum E3 str. Alaska E43 pullulanase YP_001922107.1 2888167 R 508767 CDS YP_001922108.1 188590015 6318625 complement(2890480..2890593) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2890593 6318625 CLH_2731 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922108.1 2890480 R 508767 CDS YP_001922109.1 188589287 6318172 complement(2890620..2892116) 1 NC_010723.1 identified by match to protein family HMM PF00209; sodium/proline symporter 2892116 6318172 CLH_2732 Clostridium botulinum E3 str. Alaska E43 sodium/proline symporter YP_001922109.1 2890620 R 508767 CDS YP_001922110.1 188588579 6320464 2892355..2892642 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2892642 6320464 CLH_2733 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922110.1 2892355 D 508767 CDS YP_001922111.1 188587927 6320594 complement(2892952..2894376) 1 NC_010723.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03711; arginine/lysine decarboxylase 2894376 6320594 CLH_2734 Clostridium botulinum E3 str. Alaska E43 arginine/lysine decarboxylase YP_001922111.1 2892952 R 508767 CDS YP_001922112.1 188588088 6318982 complement(2894625..2895830) 1 NC_010723.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; zinc protease 2895830 6318982 CLH_2735 Clostridium botulinum E3 str. Alaska E43 zinc protease YP_001922112.1 2894625 R 508767 CDS YP_001922113.1 188590659 6320022 complement(2896193..2897872) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; Methyl-accepting chemotaxis protein 2897872 6320022 CLH_2736 Clostridium botulinum E3 str. Alaska E43 Methyl-accepting chemotaxis protein YP_001922113.1 2896193 R 508767 CDS YP_001922114.1 188590051 6320168 complement(2898200..2899555) 1 NC_010723.1 identified by match to protein family HMM PF04055; heme biosynthesis 2899555 6320168 CLH_2737 Clostridium botulinum E3 str. Alaska E43 heme biosynthesis YP_001922114.1 2898200 R 508767 CDS YP_001922115.1 188589380 6317581 complement(2899627..2899764) 1 NC_010723.1 hypothetical protein 2899764 6317581 CLH_2738 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922115.1 2899627 R 508767 CDS YP_001922116.1 188589072 6318136 complement(2900072..2902000) 1 NC_010723.1 molecular chaperone; heat shock protein 90 2902000 6318136 CLH_2739 Clostridium botulinum E3 str. Alaska E43 heat shock protein 90 YP_001922116.1 2900072 R 508767 CDS YP_001922117.1 188589811 6319443 complement(2902201..2905743) 1 NC_010723.1 identified by match to protein family HMM PF02463; exonuclease SbcC 2905743 6319443 CLH_2740 Clostridium botulinum E3 str. Alaska E43 exonuclease SbcC YP_001922117.1 2902201 R 508767 CDS YP_001922118.1 188588355 6317482 complement(2905730..2906950) 1 NC_010723.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00619; DNA repair exonuclease 2906950 6317482 CLH_2741 Clostridium botulinum E3 str. Alaska E43 DNA repair exonuclease YP_001922118.1 2905730 R 508767 CDS YP_001922119.1 188588873 6319898 complement(2906964..2907521) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2907521 6319898 CLH_2742 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001922119.1 2906964 R 508767 CDS YP_001922120.1 188589627 6319021 2908042..2909088 1 NC_010723.1 identified by match to protein family HMM PF02698; integral membrane protein 2909088 6319021 CLH_2743 Clostridium botulinum E3 str. Alaska E43 integral membrane protein YP_001922120.1 2908042 D 508767 CDS YP_001922121.1 188590316 6318540 complement(2909284..2910039) 1 NC_010723.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 2910039 surE 6318540 surE Clostridium botulinum E3 str. Alaska E43 stationary phase survival protein SurE YP_001922121.1 2909284 R 508767 CDS YP_001922122.1 188590053 6319912 2910458..2912386 1 NC_010723.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872; 2`,3`-cyclic-nucleotide 2`-phosphodiesterase 2912386 6319912 CLH_2745 Clostridium botulinum E3 str. Alaska E43 2`,3`-cyclic-nucleotide 2`-phosphodiesterase YP_001922122.1 2910458 D 508767 CDS YP_001922123.1 188587734 6317583 complement(2912507..2914186) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis sensory transducer 2914186 6317583 CLH_2746 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis sensory transducer YP_001922123.1 2912507 R 508767 CDS YP_001922124.1 188588161 6319469 2914644..2915282 1 NC_010723.1 hypothetical protein 2915282 6319469 CLH_2747 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922124.1 2914644 D 508767 CDS YP_001922125.1 188589168 6319243 complement(2915433..2916227) 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YidA 2916227 6319243 CLH_2748 Clostridium botulinum E3 str. Alaska E43 phosphatase YidA YP_001922125.1 2915433 R 508767 CDS YP_001922126.1 188590646 6318152 complement(2916381..2917358) 1 NC_010723.1 identified by match to protein family HMM TIGR01921; diaminopimelate dehydrogenase 2917358 6318152 CLH_2749 Clostridium botulinum E3 str. Alaska E43 diaminopimelate dehydrogenase YP_001922126.1 2916381 R 508767 CDS YP_001922127.1 188588076 6319259 complement(2917623..2917754) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2917754 6319259 CLH_2750 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922127.1 2917623 R 508767 CDS YP_001922128.1 188590086 6320267 2917878..2918969 1 NC_010723.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08279; sugar kinase, ribokinase family 2918969 6320267 CLH_2751 Clostridium botulinum E3 str. Alaska E43 sugar kinase, ribokinase family YP_001922128.1 2917878 D 508767 CDS YP_001922129.1 188587935 6317462 complement(2919121..2920272) 1 NC_010723.1 identified by match to protein family HMM PF00465; alcohol dehydrogenase 2920272 6317462 CLH_2752 Clostridium botulinum E3 str. Alaska E43 alcohol dehydrogenase YP_001922129.1 2919121 R 508767 CDS YP_001922130.1 188588699 6320596 complement(2920363..2921055) 1 NC_010723.1 identified by match to protein family HMM PF00697; N-(5'phosphoribosyl)anthranilate isomerase 2921055 trpF 6320596 trpF Clostridium botulinum E3 str. Alaska E43 N-(5'phosphoribosyl)anthranilate isomerase YP_001922130.1 2920363 R 508767 CDS YP_001922131.1 188589215 6318618 complement(2921060..2922004) 1 NC_010723.1 identified by match to protein family HMM PF00294; kinase, pfkB family 2922004 6318618 CLH_2754 Clostridium botulinum E3 str. Alaska E43 kinase, pfkB family YP_001922131.1 2921060 R 508767 CDS YP_001922132.1 188588115 6317508 complement(2922425..2923357) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2923357 6317508 CLH_2755 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922132.1 2922425 R 508767 CDS YP_001922133.1 188588653 6319725 complement(2923394..2923978) 1 NC_010723.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; RNA polymerase sigma-70 factor 2923978 6319725 CLH_2756 Clostridium botulinum E3 str. Alaska E43 RNA polymerase sigma-70 factor YP_001922133.1 2923394 R 508767 CDS YP_001922134.1 188589595 6317373 complement(2924284..2924919) 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; phosphatase 2924919 6317373 CLH_2757 Clostridium botulinum E3 str. Alaska E43 phosphatase YP_001922134.1 2924284 R 508767 CDS YP_001922135.1 188590700 6318027 complement(2924969..2925952) 1 NC_010723.1 identified by match to protein family HMM PF00480; putative ROK family protein 2925952 6318027 CLH_2758 Clostridium botulinum E3 str. Alaska E43 putative ROK family protein YP_001922135.1 2924969 R 508767 CDS YP_001922136.1 188589099 6318403 complement(2926176..2926994) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2926994 6318403 CLH_2759 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922136.1 2926176 R 508767 CDS YP_001922137.1 188590014 6318924 complement(2927206..2928663) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensory transduction histidine kinase 2928663 6318924 CLH_2760 Clostridium botulinum E3 str. Alaska E43 sensory transduction histidine kinase YP_001922137.1 2927206 R 508767 CDS YP_001922138.1 188587839 6318171 complement(2928669..2929325) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 2929325 6318171 CLH_2761 Clostridium botulinum E3 str. Alaska E43 response regulator YP_001922138.1 2928669 R 508767 CDS YP_001922139.1 188590216 6318690 complement(2929590..2930876) 1 NC_010723.1 identified by match to protein family HMM PF04231; extracellular ribonuclease 2930876 6318690 CLH_2762 Clostridium botulinum E3 str. Alaska E43 extracellular ribonuclease YP_001922139.1 2929590 R 508767 CDS YP_001922140.1 188589837 6317618 complement(2931175..2932161) 1 NC_010723.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase family protein 2932161 6317618 CLH_2763 Clostridium botulinum E3 str. Alaska E43 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_001922140.1 2931175 R 508767 CDS YP_001922141.1 188588787 6320141 complement(2932209..2933240) 1 NC_010723.1 pts system, fructose-specific iibc component 2933240 6320141 CLH_2764 Clostridium botulinum E3 str. Alaska E43 pts system, fructose-specific iibc component YP_001922141.1 2932209 R 508767 CDS YP_001922142.1 188590034 6317975 complement(2933363..2934163) 1 NC_010723.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; putative regulator of efflux transporter 2934163 6317975 CLH_2765 Clostridium botulinum E3 str. Alaska E43 putative regulator of efflux transporter YP_001922142.1 2933363 R 508767 CDS YP_001922143.1 188590716 6318312 complement(2934489..2934605) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2934605 6318312 CLH_2766 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922143.1 2934489 R 508767 CDS YP_001922144.1 188588727 6319298 complement(2934562..2935251) 1 NC_010723.1 radical SAM domain protein 2935251 6319298 CLH_2767 Clostridium botulinum E3 str. Alaska E43 radical SAM domain protein YP_001922144.1 2934562 R 508767 CDS YP_001922145.1 188587835 6317680 complement(2935238..2935813) 1 NC_010723.1 integral membrane protein 2935813 6317680 CLH_2768 Clostridium botulinum E3 str. Alaska E43 integral membrane protein YP_001922145.1 2935238 R 508767 CDS YP_001922146.1 188589467 6317554 complement(2935969..2936949) 1 NC_010723.1 identified by match to protein family HMM PF01156; nucleoside hydrolase, IUNH family 2936949 6317554 CLH_2769 Clostridium botulinum E3 str. Alaska E43 nucleoside hydrolase, IUNH family YP_001922146.1 2935969 R 508767 CDS YP_001922147.1 188588590 6320357 complement(2937487..2938368) 1 NC_010723.1 identified by match to protein family HMM PF00892; transporter 2938368 6320357 CLH_2770 Clostridium botulinum E3 str. Alaska E43 transporter YP_001922147.1 2937487 R 508767 CDS YP_001922148.1 188587682 6318612 complement(2939180..2940019) 1 NC_010723.1 identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; nicotinate-nucleotide diphosphorylase (carboxylating) 2940019 nadC 6318612 nadC Clostridium botulinum E3 str. Alaska E43 nicotinate-nucleotide diphosphorylase (carboxylating) YP_001922148.1 2939180 R 508767 CDS YP_001922149.1 188590032 6318482 complement(2939997..2941310) 1 NC_010723.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2941310 6318482 CLH_2772 Clostridium botulinum E3 str. Alaska E43 L-aspartate oxidase YP_001922149.1 2939997 R 508767 CDS YP_001922150.1 188589124 6317909 complement(2941316..2942227) 1 NC_010723.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 2942227 nadA 6317909 nadA Clostridium botulinum E3 str. Alaska E43 quinolinate synthetase YP_001922150.1 2941316 R 508767 CDS YP_001922151.1 188588209 6318287 2942548..2943090 1 NC_010723.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubredoxin/rubrerythrin 2943090 6318287 CLH_2774 Clostridium botulinum E3 str. Alaska E43 rubredoxin/rubrerythrin YP_001922151.1 2942548 D 508767 CDS YP_001922152.1 188589040 6319683 2943231..2943548 1 NC_010723.1 identified by match to protein family HMM PF07561; hypothetical protein 2943548 6319683 CLH_2775 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922152.1 2943231 D 508767 CDS YP_001922153.1 188588280 6318971 2943850..2944476 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2944476 6318971 CLH_2776 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922153.1 2943850 D 508767 CDS YP_001922154.1 188590429 6319801 complement(2944697..2944870) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2944870 6319801 CLH_2777 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922154.1 2944697 R 508767 CDS YP_001922155.1 188589733 6320477 complement(2944942..2947086) 1 NC_010723.1 identified by match to protein family HMM PF01926; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; match to protein family HMM TIGR00231; match to protein family HMM TIGR00437; ferrous iron transport protein B 2947086 feoB 6320477 feoB Clostridium botulinum E3 str. Alaska E43 ferrous iron transport protein B YP_001922155.1 2944942 R 508767 CDS YP_001922156.1 188589988 6318676 complement(2947159..2947380) 1 NC_010723.1 identified by match to protein family HMM PF04023; hypothetical protein 2947380 6318676 CLH_2779 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922156.1 2947159 R 508767 CDS YP_001922157.1 188587637 6319892 complement(2947394..2947603) 1 NC_010723.1 identified by match to protein family HMM PF04023; hypothetical protein 2947603 6319892 CLH_2780 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922157.1 2947394 R 508767 CDS YP_001922158.1 188588617 6320017 complement(2948027..2949361) 1 NC_010723.1 CoADR; specific for coenzyme A disulfide; requires NADH; involved in protecting cells against reactive oxygen species by recycling coenzyme A disulfide which can reduce hydrogen peroxide; coenzyme A disulfide reductase 2949361 6320017 CLH_2781 Clostridium botulinum E3 str. Alaska E43 coenzyme A disulfide reductase YP_001922158.1 2948027 R 508767 CDS YP_001922159.1 188589334 6317486 complement(2949977..2950606) 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; hydrolase 2950606 6317486 CLH_2782 Clostridium botulinum E3 str. Alaska E43 hydrolase YP_001922159.1 2949977 R 508767 CDS YP_001922160.1 188590513 6318440 2950935..2952248 1 NC_010723.1 identified by match to protein family HMM PF04055; radical SAM 2952248 6318440 CLH_2783 Clostridium botulinum E3 str. Alaska E43 radical SAM YP_001922160.1 2950935 D 508767 CDS YP_001922161.1 188588868 6319151 2952251..2952991 1 NC_010723.1 hypothetical protein 2952991 6319151 CLH_2784 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922161.1 2952251 D 508767 CDS YP_001922162.1 188589006 6318447 complement(2953132..2955147) 1 NC_010723.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649; endopeptidase O 2955147 6318447 CLH_2785 Clostridium botulinum E3 str. Alaska E43 endopeptidase O YP_001922162.1 2953132 R 508767 CDS YP_001922163.1 188589697 6319900 complement(2955385..2957076) 1 NC_010723.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis sensory transducer 2957076 6319900 CLH_2786 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis sensory transducer YP_001922163.1 2955385 R 508767 CDS YP_001922164.1 188589223 6319676 2957334..2957501 1 NC_010723.1 hypothetical protein 2957501 6319676 CLH_2787 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922164.1 2957334 D 508767 CDS YP_001922165.1 188588294 6317472 2957517..2957768 1 NC_010723.1 spore coat protein CotJB 2957768 6317472 CLH_2788 Clostridium botulinum E3 str. Alaska E43 spore coat protein CotJB YP_001922165.1 2957517 D 508767 CDS YP_001922166.1 188588663 6319745 2957783..2958346 1 NC_010723.1 identified by match to protein family HMM PF05067; protein cotJC 2958346 6319745 CLH_2789 Clostridium botulinum E3 str. Alaska E43 protein cotJC YP_001922166.1 2957783 D 508767 CDS YP_001922167.1 188589554 6317535 complement(2958498..2959463) 1 NC_010723.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM TIGR02912; sulfite reductase subunit C 2959463 asrC 6317535 asrC Clostridium botulinum E3 str. Alaska E43 sulfite reductase subunit C YP_001922167.1 2958498 R 508767 CDS YP_001922168.1 188587555 6318382 complement(2959476..2960270) 1 NC_010723.1 with AsrAC catalyzes the reduction of sulfite to hydrogen sulfide; anaerobic sulfite reductase subunit B 2960270 asrB 6318382 asrB Clostridium botulinum E3 str. Alaska E43 anaerobic sulfite reductase subunit B YP_001922168.1 2959476 R 508767 CDS YP_001922169.1 188588668 6318378 complement(2960263..2961273) 1 NC_010723.1 identified by match to protein family HMM TIGR02910; sulfite reductase subunit A 2961273 asrA 6318378 asrA Clostridium botulinum E3 str. Alaska E43 sulfite reductase subunit A YP_001922169.1 2960263 R 508767 CDS YP_001922170.1 188589955 6318230 complement(2961288..2962055) 1 NC_010723.1 identified by match to protein family HMM PF01226; formate/nitrite family of transporter 2962055 6318230 CLH_2793 Clostridium botulinum E3 str. Alaska E43 formate/nitrite family of transporter YP_001922170.1 2961288 R 508767 CDS YP_001922171.1 188590128 6319534 complement(2962149..2962601) 1 NC_010723.1 identified by match to protein family HMM PF00325; CarD family transcriptional regulator 2962601 6319534 CLH_2794 Clostridium botulinum E3 str. Alaska E43 CarD family transcriptional regulator YP_001922171.1 2962149 R 508767 CDS YP_001922172.1 188588847 6317454 2962624..2962866 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 2962866 6317454 CLH_2795 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922172.1 2962624 D 508767 CDS YP_001922173.1 188589986 6318630 complement(2962903..2963856) 1 NC_010723.1 identified by match to protein family HMM TIGR01764; periplasmic molybdate-binding protein/domain 2963856 6318630 CLH_2796 Clostridium botulinum E3 str. Alaska E43 periplasmic molybdate-binding protein/domain YP_001922173.1 2962903 R 508767 CDS YP_001922174.1 188589553 6319890 2964121..2964942 1 NC_010723.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256; molybdate ABC transporter periplasmic molybdate-binding protein 2964942 modA 6319890 modA Clostridium botulinum E3 str. Alaska E43 molybdate ABC transporter periplasmic molybdate-binding protein YP_001922174.1 2964121 D 508767 CDS YP_001922175.1 188590294 6318810 2964965..2965648 1 NC_010723.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02141; molybdate ABC transporter permease 2965648 modB 6318810 modB Clostridium botulinum E3 str. Alaska E43 molybdate ABC transporter permease YP_001922175.1 2964965 D 508767 CDS YP_001922176.1 188589103 6318766 2965650..2966699 1 NC_010723.1 identified by match to protein family HMM PF00005; putrescine transport ATP-binding protein PotG 2966699 6318766 CLH_2799 Clostridium botulinum E3 str. Alaska E43 putrescine transport ATP-binding protein PotG YP_001922176.1 2965650 D 508767 CDS YP_001922177.1 188588170 6320562 complement(2966899..2968290) 1 NC_010723.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 2968290 gltA 6320562 gltA Clostridium botulinum E3 str. Alaska E43 putative oxidoreductase YP_001922177.1 2966899 R 508767 CDS YP_001922178.1 188590520 6319473 complement(2968290..2969177) 1 NC_010723.1 identified by match to protein family HMM PF00175; ferredoxin-NADP(+) reductase subunit alpha 2969177 gltD 6319473 gltD Clostridium botulinum E3 str. Alaska E43 ferredoxin-NADP(+) reductase subunit alpha YP_001922178.1 2968290 R 508767 CDS YP_001922179.1 188589393 6317958 complement(2969489..2969959) 1 NC_010723.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2969959 smpB 6317958 smpB Clostridium botulinum E3 str. Alaska E43 SsrA-binding protein YP_001922179.1 2969489 R 508767 CDS YP_001922180.1 188588711 6318652 complement(2970135..2972375) 1 NC_010723.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; ribonuclease R 2972375 rnr 6318652 rnr Clostridium botulinum E3 str. Alaska E43 ribonuclease R YP_001922180.1 2970135 R 508767 CDS YP_001922181.1 188587562 6318134 complement(2972599..2974626) 1 NC_010723.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 2974626 hppA 6318134 hppA Clostridium botulinum E3 str. Alaska E43 membrane-bound proton-translocating pyrophosphatase YP_001922181.1 2972599 R 508767 CDS YP_001922182.1 188589375 6319552 complement(2975096..2975329) 1 NC_010723.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 2975329 secG 6319552 secG Clostridium botulinum E3 str. Alaska E43 preprotein translocase subunit SecG YP_001922182.1 2975096 R 508767 CDS YP_001922183.1 188589978 6318531 complement(2975610..2976905) 1 NC_010723.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2976905 eno 6318531 eno Clostridium botulinum E3 str. Alaska E43 phosphopyruvate hydratase YP_001922183.1 2975610 R 508767 CDS YP_001922184.1 188588848 6318334 complement(2977213..2977797) 1 NC_010723.1 hypothetical protein 2977797 6318334 CLH_2807 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922184.1 2977213 R 508767 CDS YP_001922185.1 188588099 6318631 complement(2978051..2979589) 1 NC_010723.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 2979589 gpmI 6318631 gpmI Clostridium botulinum E3 str. Alaska E43 phosphoglyceromutase YP_001922185.1 2978051 R 508767 CDS YP_001922186.1 188588226 6319252 complement(2979956..2980504) 1 NC_010723.1 viral A-type inclusion protein repeat containing protein 2980504 6319252 CLH_2809 Clostridium botulinum E3 str. Alaska E43 viral A-type inclusion protein repeat containing protein YP_001922186.1 2979956 R 508767 CDS YP_001922187.1 188590613 6319648 complement(2980603..2981205) 1 NC_010723.1 identified by match to protein family HMM PF01966; metal dependent phosphohydrolase 2981205 6319648 CLH_2810 Clostridium botulinum E3 str. Alaska E43 metal dependent phosphohydrolase YP_001922187.1 2980603 R 508767 CDS YP_001922188.1 188590509 6318110 2981477..2982541 1 NC_010723.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 2982541 6318110 CLH_2811 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001922188.1 2981477 D 508767 CDS YP_001922189.1 188589792 6318079 complement(2982647..2983393) 1 NC_010723.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 2983393 tpiA 6318079 tpiA Clostridium botulinum E3 str. Alaska E43 triosephosphate isomerase YP_001922189.1 2982647 R 508767 CDS YP_001922190.1 188587791 6319479 complement(2983517..2984707) 1 NC_010723.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 2984707 pgk 6319479 pgk Clostridium botulinum E3 str. Alaska E43 phosphoglycerate kinase YP_001922190.1 2983517 R 508767 CDS YP_001922191.1 188590347 6320579 complement(2984824..2985840) 1 NC_010723.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase, type I 2985840 gap 6320579 gap Clostridium botulinum E3 str. Alaska E43 glyceraldehyde-3-phosphate dehydrogenase, type I YP_001922191.1 2984824 R 508767 CDS YP_001922192.1 188588417 6317466 complement(2985913..2986944) 1 NC_010723.1 identified by match to protein family HMM PF04198; transcriptional regulator 2986944 6317466 CLH_2815 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001922192.1 2985913 R 508767 CDS YP_001922193.1 188588319 6319756 complement(2987184..2988566) 1 NC_010723.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 2988566 rpoN 6319756 rpoN Clostridium botulinum E3 str. Alaska E43 RNA polymerase factor sigma-54 YP_001922193.1 2987184 R 508767 CDS YP_001922194.1 188590531 6319948 complement(2988808..2989644) 1 NC_010723.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 2989644 6319948 CLH_2817 Clostridium botulinum E3 str. Alaska E43 DegV family protein YP_001922194.1 2988808 R 508767 CDS YP_001922195.1 188589587 6319124 complement(2989663..2990124) 1 NC_010723.1 identified by match to protein family HMM PF00588; tRNA/rRNA methyltransferase 2990124 6319124 CLH_2818 Clostridium botulinum E3 str. Alaska E43 tRNA/rRNA methyltransferase YP_001922195.1 2989663 R 508767 CDS YP_001922196.1 188590465 6318777 complement(2990370..2991881) 1 NC_010723.1 identified by match to protein family HMM PF04294; match to protein family HMM PF07501; vancomycin B-type resistance protein VanW 2991881 6318777 CLH_2819 Clostridium botulinum E3 str. Alaska E43 vancomycin B-type resistance protein VanW YP_001922196.1 2990370 R 508767 CDS YP_001922197.1 188588351 6320263 complement(2992106..2993047) 1 NC_010723.1 identified by match to protein family HMM PF01183; muramidase 2993047 6320263 CLH_2820 Clostridium botulinum E3 str. Alaska E43 muramidase YP_001922197.1 2992106 R 508767 CDS YP_001922198.1 188589011 6319708 complement(2993132..2994655) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; two-component sensor kinase 2994655 6319708 CLH_2821 Clostridium botulinum E3 str. Alaska E43 two-component sensor kinase YP_001922198.1 2993132 R 508767 CDS YP_001922199.1 188589285 6319466 complement(2994645..2995355) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; regulatory protein VanR 2995355 6319466 CLH_2822 Clostridium botulinum E3 str. Alaska E43 regulatory protein VanR YP_001922199.1 2994645 R 508767 CDS YP_001922200.1 188590367 6317428 complement(2995803..2996708) 1 NC_010723.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 2996708 ddl 6317428 ddl Clostridium botulinum E3 str. Alaska E43 D-alanine--D-alanine ligase YP_001922200.1 2995803 R 508767 CDS YP_001922201.1 188587888 6318291 complement(2997016..2997642) 1 NC_010723.1 identified by match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 2997642 nth 6318291 nth Clostridium botulinum E3 str. Alaska E43 endonuclease III YP_001922201.1 2997016 R 508767 CDS YP_001922202.1 188588097 6319870 complement(2997661..2998365) 1 NC_010723.1 identified by match to protein family HMM PF01553; sn-glycerol-3-phosphate acyltransferase 2998365 6319870 CLH_2825 Clostridium botulinum E3 str. Alaska E43 sn-glycerol-3-phosphate acyltransferase YP_001922202.1 2997661 R 508767 CDS YP_001922203.1 188590517 6319216 complement(2998412..2999413) 1 NC_010723.1 identified by match to protein family HMM PF08331; iron-sulfur cluster-binding protein 2999413 6319216 CLH_2826 Clostridium botulinum E3 str. Alaska E43 iron-sulfur cluster-binding protein YP_001922203.1 2998412 R 508767 CDS YP_001922204.1 188589949 6320170 complement(2999425..3000009) 1 NC_010723.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172; serine O-acetyltransferase 3000009 cysE 6320170 cysE Clostridium botulinum E3 str. Alaska E43 serine O-acetyltransferase YP_001922204.1 2999425 R 508767 CDS YP_001922205.1 188590671 6319695 complement(3000123..3001034) 1 NC_010723.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase A 3001034 cysK 6319695 cysK Clostridium botulinum E3 str. Alaska E43 cysteine synthase A YP_001922205.1 3000123 R 508767 CDS YP_001922206.1 188589265 6317903 complement(3001688..3002938) 1 NC_010723.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03448; hypothetical protein 3002938 6317903 CLH_2829 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922206.1 3001688 R 508767 CDS YP_001922207.1 188588732 6318596 3003794..3005842 1 NC_010723.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497; hypothetical protein 3005842 6318596 CLH_2830 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922207.1 3003794 D 508767 CDS YP_001922208.1 188589581 6320049 complement(3005980..3006636) 1 NC_010723.1 hypothetical protein 3006636 6320049 CLH_2831 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922208.1 3005980 R 508767 CDS YP_001922209.1 188588472 6319633 complement(3006723..3007601) 1 NC_010723.1 similar to YegS from E. coli; putative lipid kinase 3007601 6319633 CLH_2832 Clostridium botulinum E3 str. Alaska E43 putative lipid kinase YP_001922209.1 3006723 R 508767 CDS YP_001922210.1 188587744 6319137 3007820..3008341 1 NC_010723.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; CDP-diacylglycerol--serine O-phosphatidyltransferase 3008341 pssA 6319137 pssA Clostridium botulinum E3 str. Alaska E43 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_001922210.1 3007820 D 508767 CDS YP_001922211.1 188589894 6319762 complement(3008404..3008763) 1 NC_010723.1 hypothetical protein 3008763 6319762 CLH_2834 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922211.1 3008404 R 508767 CDS YP_001922212.1 188588789 6318548 complement(3009062..3009460) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3009460 6318548 CLH_2835 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922212.1 3009062 R 508767 CDS YP_001922213.1 188588048 6318348 complement(3009475..3010020) 1 NC_010723.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubrerythrin 3010020 6318348 CLH_2836 Clostridium botulinum E3 str. Alaska E43 rubrerythrin YP_001922213.1 3009475 R 508767 CDS YP_001922214.1 188590318 6319007 complement(3010216..3011586) 1 NC_010723.1 identified by match to protein family HMM PF04293; stage V sporulation protein R 3011586 6319007 CLH_2837 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein R YP_001922214.1 3010216 R 508767 CDS YP_001922215.1 188589436 6319914 complement(3011591..3012766) 1 NC_010723.1 identified by match to protein family HMM PF04285; match to protein family HMM TIGR02877; hypothetical protein 3012766 yhbH 6319914 yhbH Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922215.1 3011591 R 508767 CDS YP_001922216.1 188587669 6317833 complement(3012775..3014697) 1 NC_010723.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298; serine protein kinase 3014697 6317833 CLH_2839 Clostridium botulinum E3 str. Alaska E43 serine protein kinase YP_001922216.1 3012775 R 508767 CDS YP_001922217.1 188588714 6319806 complement(3014823..3014939) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3014939 6319806 CLH_2840 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922217.1 3014823 R 508767 CDS YP_001922218.1 188590791 6317764 complement(3014968..3016731) 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389; ATP-dependent DNA helicase RecQ 3016731 recQ 6317764 recQ Clostridium botulinum E3 str. Alaska E43 ATP-dependent DNA helicase RecQ YP_001922218.1 3014968 R 508767 CDS YP_001922219.1 188590099 6319291 complement(3016757..3017275) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3017275 6319291 CLH_2842 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922219.1 3016757 R 508767 CDS YP_001922220.1 188590335 6317326 complement(3017279..3017680) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3017680 6317326 CLH_2843 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922220.1 3017279 R 508767 CDS YP_001922221.1 188589405 6318602 3017834..3018412 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3018412 6318602 CLH_2844 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922221.1 3017834 D 508767 CDS YP_001922222.1 188588918 6319083 complement(3018576..3020552) 1 NC_010723.1 antimicrobial peptide ABC transporter permease 3020552 6319083 CLH_2845 Clostridium botulinum E3 str. Alaska E43 antimicrobial peptide ABC transporter permease YP_001922222.1 3018576 R 508767 CDS YP_001922223.1 188588016 6319108 complement(3020545..3021312) 1 NC_010723.1 identified by match to protein family HMM PF00005; bacitracin export ATP-binding protein BceA 3021312 6319108 CLH_2846 Clostridium botulinum E3 str. Alaska E43 bacitracin export ATP-binding protein BceA YP_001922223.1 3020545 R 508767 CDS YP_001922224.1 188588247 6319483 complement(3021578..3022594) 1 NC_010723.1 identified by match to protein family HMM PF02518; integral membrane sensor signal transduction histidine kinase 3022594 6319483 CLH_2847 Clostridium botulinum E3 str. Alaska E43 integral membrane sensor signal transduction histidine kinase YP_001922224.1 3021578 R 508767 CDS YP_001922225.1 188590529 6319727 complement(3022597..3023271) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two component transcriptional regulator, winged helix family 3023271 6319727 CLH_2848 Clostridium botulinum E3 str. Alaska E43 two component transcriptional regulator, winged helix family YP_001922225.1 3022597 R 508767 CDS YP_001922226.1 188587795 6319122 complement(3023487..3023843) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3023843 6319122 CLH_2849 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922226.1 3023487 R 508767 CDS YP_001922227.1 188590113 6317800 3024112..3024465 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3024465 6317800 CLH_2850 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922227.1 3024112 D 508767 CDS YP_001922228.1 188590555 6320083 complement(3024571..3024984) 1 NC_010723.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3024984 6320083 CLH_2851 Clostridium botulinum E3 str. Alaska E43 MarR family transcriptional regulator YP_001922228.1 3024571 R 508767 CDS YP_001922229.1 188589608 6318122 3025159..3025617 1 NC_010723.1 hypothetical protein 3025617 6318122 CLH_2852 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922229.1 3025159 D 508767 CDS YP_001922230.1 188587844 6318886 complement(3025800..3026390) 1 NC_010723.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubrerythrin 3026390 6318886 CLH_2853 Clostridium botulinum E3 str. Alaska E43 rubrerythrin YP_001922230.1 3025800 R 508767 CDS YP_001922231.1 188590634 6317623 complement(3026594..3027553) 1 NC_010723.1 identified by match to protein family HMM PF01734; hypothetical protein 3027553 6317623 CLH_2854 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922231.1 3026594 R 508767 CDS YP_001922232.1 188588371 6317874 complement(3027776..3028408) 1 NC_010723.1 identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693; thiamine-phosphate pyrophosphorylase 3028408 thiE 6317874 thiE Clostridium botulinum E3 str. Alaska E43 thiamine-phosphate pyrophosphorylase YP_001922232.1 3027776 R 508767 CDS YP_001922233.1 188587732 6319979 complement(3028588..3029424) 1 NC_010723.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 3029424 thiM 6319979 thiM Clostridium botulinum E3 str. Alaska E43 hydroxyethylthiazole kinase YP_001922233.1 3028588 R 508767 CDS YP_001922234.1 188590276 6318717 complement(3029617..3030402) 1 NC_010723.1 identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097; phosphomethylpyrimidine kinase 3030402 thiD 6318717 thiD Clostridium botulinum E3 str. Alaska E43 phosphomethylpyrimidine kinase YP_001922234.1 3029617 R 508767 CDS YP_001922235.1 188589536 6318155 complement(3030455..3030583) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3030583 6318155 CLH_2858 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922235.1 3030455 R 508767 CDS YP_001922236.1 188588014 6319240 complement(3030866..3031744) 1 NC_010723.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718; L-serine dehydratase, iron-sulfur-dependent subunit alpha 3031744 sdaAA 6319240 sdaAA Clostridium botulinum E3 str. Alaska E43 L-serine dehydratase, iron-sulfur-dependent subunit alpha YP_001922236.1 3030866 R 508767 CDS YP_001922237.1 188590655 6319481 complement(3031746..3032432) 1 NC_010723.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; L-serine dehydratase, iron-sulfur-dependent subunit beta 3032432 sdaAB 6319481 sdaAB Clostridium botulinum E3 str. Alaska E43 L-serine dehydratase, iron-sulfur-dependent subunit beta YP_001922237.1 3031746 R 508767 CDS YP_001922238.1 188588485 6319279 complement(3032717..3034363) 1 NC_010723.1 identified by match to protein family HMM PF00485; phosphoribulokinase 3034363 6319279 CLH_2861 Clostridium botulinum E3 str. Alaska E43 phosphoribulokinase YP_001922238.1 3032717 R 508767 CDS YP_001922239.1 188588401 6320309 3034499..3035197 1 NC_010723.1 identified by match to protein family HMM PF04239; hypothetical protein 3035197 6320309 CLH_2862 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922239.1 3034499 D 508767 CDS YP_001922240.1 188590050 6319486 3035197..3035577 1 NC_010723.1 hypothetical protein 3035577 6319486 CLH_2863 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922240.1 3035197 D 508767 CDS YP_001922241.1 188589316 6317577 3035771..3036703 1 NC_010723.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859; fructose-1,6-bisphosphate aldolase 3036703 fba 6317577 fba Clostridium botulinum E3 str. Alaska E43 fructose-1,6-bisphosphate aldolase YP_001922241.1 3035771 D 508767 CDS YP_001922242.1 188589844 6317637 3037425..3038648 1 NC_010723.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 3038648 argG 6317637 argG Clostridium botulinum E3 str. Alaska E43 argininosuccinate synthase YP_001922242.1 3037425 D 508767 CDS YP_001922243.1 188589144 6319235 3038651..3040048 1 NC_010723.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 3040048 argH 6319235 argH Clostridium botulinum E3 str. Alaska E43 argininosuccinate lyase YP_001922243.1 3038651 D 508767 CDS YP_001922244.1 188588941 6318852 3040041..3041075 1 NC_010723.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 3041075 argC 6318852 argC Clostridium botulinum E3 str. Alaska E43 N-acetyl-gamma-glutamyl-phosphate reductase YP_001922244.1 3040041 D 508767 CDS YP_001922245.1 188587805 6318919 3041095..3042318 1 NC_010723.1 identified by match to protein family HMM PF01960; match to protein family HMM TIGR00120; arginine biosynthesis bifunctional protein ArgJ 3042318 argJ 6318919 argJ Clostridium botulinum E3 str. Alaska E43 arginine biosynthesis bifunctional protein ArgJ YP_001922245.1 3041095 D 508767 CDS YP_001922246.1 188590394 6319773 3042351..3043205 1 NC_010723.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 3043205 argB 6319773 argB Clostridium botulinum E3 str. Alaska E43 acetylglutamate kinase YP_001922246.1 3042351 D 508767 CDS YP_001922247.1 188589488 6318011 3043219..3044400 1 NC_010723.1 identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; acetylornithine aminotransferase 3044400 6318011 CLH_2870 Clostridium botulinum E3 str. Alaska E43 acetylornithine aminotransferase YP_001922247.1 3043219 D 508767 CDS YP_001922248.1 188589569 6317840 3044494..3045414 1 NC_010723.1 identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00658; ornithine carbamoyltransferase 3045414 argF 6317840 argF Clostridium botulinum E3 str. Alaska E43 ornithine carbamoyltransferase YP_001922248.1 3044494 D 508767 CDS YP_001922249.1 188588428 6319643 3045791..3047506 1 NC_010723.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; putative sensory box/ggdef family protein 3047506 6319643 CLH_2872 Clostridium botulinum E3 str. Alaska E43 putative sensory box/ggdef family protein YP_001922249.1 3045791 D 508767 CDS YP_001922250.1 188588192 6319282 complement(3047705..3048745) 1 NC_010723.1 hypothetical protein 3048745 6319282 CLH_2873 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922250.1 3047705 R 508767 CDS YP_001922251.1 188590163 6318070 3048922..3049482 1 NC_010723.1 identified by match to protein family HMM PF01928; adenylate cyclase 3049482 6318070 CLH_2874 Clostridium botulinum E3 str. Alaska E43 adenylate cyclase YP_001922251.1 3048922 D 508767 CDS YP_001922252.1 188589107 6317674 complement(3049574..3050551) 1 NC_010723.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 3050551 manA 6317674 manA Clostridium botulinum E3 str. Alaska E43 mannose-6-phosphate isomerase YP_001922252.1 3049574 R 508767 CDS YP_001922253.1 188588206 6320419 complement(3050901..3051827) 1 NC_010723.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase 3051827 pfkB 6320419 pfkB Clostridium botulinum E3 str. Alaska E43 1-phosphofructokinase YP_001922253.1 3050901 R 508767 CDS YP_001922254.1 188590584 6319713 complement(3052201..3053058) 1 NC_010723.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3053058 gatY 6319713 gatY Clostridium botulinum E3 str. Alaska E43 tagatose-bisphosphate aldolase YP_001922254.1 3052201 R 508767 CDS YP_001922255.1 188589643 6319385 complement(3053103..3053534) 1 NC_010723.1 identified by match to protein family HMM PF03610; PTS system fructose IIA component 3053534 6319385 CLH_2878 Clostridium botulinum E3 str. Alaska E43 PTS system fructose IIA component YP_001922255.1 3053103 R 508767 CDS YP_001922256.1 188587834 6320458 complement(3053642..3054805) 1 NC_010723.1 identified by match to protein family HMM PF01380; AgaS protein 3054805 6320458 CLH_2879 Clostridium botulinum E3 str. Alaska E43 AgaS protein YP_001922256.1 3053642 R 508767 CDS YP_001922257.1 188588703 6317553 complement(3054858..3055583) 1 NC_010723.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM PF08220; GntR family transcriptional regulator 3055583 6317553 CLH_2880 Clostridium botulinum E3 str. Alaska E43 GntR family transcriptional regulator YP_001922257.1 3054858 R 508767 CDS YP_001922258.1 188589173 6318600 complement(3055846..3056694) 1 NC_010723.1 identified by match to protein family HMM PF03613; PTS system mannose/fructose/sorbose family transporter subunit IID 3056694 6318600 CLH_2881 Clostridium botulinum E3 str. Alaska E43 PTS system mannose/fructose/sorbose family transporter subunit IID YP_001922258.1 3055846 R 508767 CDS YP_001922259.1 188590112 6318046 complement(3056684..3057451) 1 NC_010723.1 identified by match to protein family HMM PF03609; PTS system sorbose-specific transporter subunit IIC 3057451 6318046 CLH_2882 Clostridium botulinum E3 str. Alaska E43 PTS system sorbose-specific transporter subunit IIC YP_001922259.1 3056684 R 508767 CDS YP_001922260.1 188589602 6320082 complement(3057511..3057987) 1 NC_010723.1 identified by match to protein family HMM PF03830; match to protein family HMM TIGR00854; PTS system mannose/fructose/sorbose family transporter subunit IIB 3057987 6320082 CLH_2883 Clostridium botulinum E3 str. Alaska E43 PTS system mannose/fructose/sorbose family transporter subunit IIB YP_001922260.1 3057511 R 508767 CDS YP_001922261.1 188590468 6317360 complement(3058128..3058670) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3058670 6317360 CLH_2884 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922261.1 3058128 R 508767 CDS YP_001922262.1 188587823 6320375 3058847..3059986 1 NC_010723.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 3059986 nagA 6320375 nagA Clostridium botulinum E3 str. Alaska E43 N-acetylglucosamine-6-phosphate deacetylase YP_001922262.1 3058847 D 508767 CDS YP_001922263.1 188588575 6320583 complement(3060190..3061023) 1 NC_010723.1 identified by match to protein family HMM PF02153; prephenate dehydrogenase 3061023 6320583 CLH_2886 Clostridium botulinum E3 str. Alaska E43 prephenate dehydrogenase YP_001922263.1 3060190 R 508767 CDS YP_001922264.1 188590003 6319198 complement(3061041..3062054) 1 NC_010723.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; 3-deoxy-7-phosphoheptulonate synthase 3062054 aroF 6319198 aroF Clostridium botulinum E3 str. Alaska E43 3-deoxy-7-phosphoheptulonate synthase YP_001922264.1 3061041 R 508767 CDS YP_001922265.1 188587814 6318832 complement(3062137..3062634) 1 NC_010723.1 identified by match to protein family HMM PF01202; shikimate kinase 3062634 aroK 6318832 aroK Clostridium botulinum E3 str. Alaska E43 shikimate kinase YP_001922265.1 3062137 R 508767 CDS YP_001922266.1 188589771 6319796 complement(3062648..3063460) 1 NC_010723.1 identified by match to protein family HMM PF01488; match to protein family HMM PF08501; match to protein family HMM TIGR00507; shikimate 5-dehydrogenase 3063460 aroE 6319796 aroE Clostridium botulinum E3 str. Alaska E43 shikimate 5-dehydrogenase YP_001922266.1 3062648 R 508767 CDS YP_001922267.1 188587887 6320252 complement(3063484..3064626) 1 NC_010723.1 identified by match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01805; P-protein 3064626 6320252 CLH_2890 Clostridium botulinum E3 str. Alaska E43 P-protein YP_001922267.1 3063484 R 508767 CDS YP_001922268.1 188588335 6319869 complement(3064833..3065906) 1 NC_010723.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3065906 aroC 6319869 aroC Clostridium botulinum E3 str. Alaska E43 chorismate synthase YP_001922268.1 3064833 R 508767 CDS YP_001922269.1 188589058 6318033 complement(3065884..3067185) 1 NC_010723.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 3067185 aroA 6318033 aroA Clostridium botulinum E3 str. Alaska E43 3-phosphoshikimate 1-carboxyvinyltransferase YP_001922269.1 3065884 R 508767 CDS YP_001922270.1 188589314 6319346 complement(3067273..3068325) 1 NC_010723.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3068325 aroB 6319346 aroB Clostridium botulinum E3 str. Alaska E43 3-dehydroquinate synthase YP_001922270.1 3067273 R 508767 CDS YP_001922271.1 188590021 6317635 complement(3068422..3069435) 1 NC_010723.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; 3-deoxy-7-phosphoheptulonate synthase 3069435 aroF 6317635 aroF Clostridium botulinum E3 str. Alaska E43 3-deoxy-7-phosphoheptulonate synthase YP_001922271.1 3068422 R 508767 CDS YP_001922272.1 188589358 6319540 complement(3069813..3071246) 1 NC_010723.1 identified by match to protein family HMM PF00614; cardiolipin synthetase 3071246 6319540 CLH_2895 Clostridium botulinum E3 str. Alaska E43 cardiolipin synthetase YP_001922272.1 3069813 R 508767 CDS YP_001922273.1 188590066 6318094 complement(3072069..3073541) 1 NC_010723.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121; sodium/proline symporter 3073541 putP 6318094 putP Clostridium botulinum E3 str. Alaska E43 sodium/proline symporter YP_001922273.1 3072069 R 508767 CDS YP_001922274.1 188587906 6320365 3074155..3076605 1 NC_010723.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 3076605 leuS 6320365 leuS Clostridium botulinum E3 str. Alaska E43 leucyl-tRNA synthetase YP_001922274.1 3074155 D 508767 CDS YP_001922275.1 188588619 6318396 complement(3076951..3079056) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis sensory transducer 3079056 6318396 CLH_2898 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis sensory transducer YP_001922275.1 3076951 R 508767 CDS YP_001922276.1 188587826 6317716 complement(3079119..3079853) 1 NC_010723.1 maltose transacetylase 3079853 6317716 CLH_2899 Clostridium botulinum E3 str. Alaska E43 maltose transacetylase YP_001922276.1 3079119 R 508767 CDS YP_001922277.1 188590148 6319186 complement(3080546..3081301) 1 NC_010723.1 hypothetical protein 3081301 6319186 CLH_2900 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922277.1 3080546 R 508767 CDS YP_001922278.1 188589247 6317725 3081558..3081887 1 NC_010723.1 identified by match to protein family HMM TIGR01911; HesB family protein 3081887 6317725 CLH_2901 Clostridium botulinum E3 str. Alaska E43 HesB family protein YP_001922278.1 3081558 D 508767 CDS YP_001922279.1 188589159 6318735 complement(3081929..3082624) 1 NC_010723.1 putative reticulocyte-binding protein 3082624 6318735 CLH_2902 Clostridium botulinum E3 str. Alaska E43 putative reticulocyte-binding protein YP_001922279.1 3081929 R 508767 CDS YP_001922280.1 188588199 6319432 complement(3082678..3084009) 1 NC_010723.1 hypothetical protein 3084009 6319432 CLH_2903 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922280.1 3082678 R 508767 CDS YP_001922281.1 188590585 6319533 complement(3084125..3085213) 1 NC_010723.1 identified by match to protein family HMM PF07728; ATPase family protein 3085213 6319533 CLH_2904 Clostridium botulinum E3 str. Alaska E43 ATPase family protein YP_001922281.1 3084125 R 508767 CDS YP_001922282.1 188588706 6320217 complement(3085468..3086247) 1 NC_010723.1 hypothetical protein 3086247 6320217 CLH_2905 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922282.1 3085468 R 508767 CDS YP_001922283.1 188587850 6318611 complement(3086326..3087117) 1 NC_010723.1 identified by match to protein family HMM PF04607; RelA/spoT family protein 3087117 6318611 CLH_2906 Clostridium botulinum E3 str. Alaska E43 RelA/spoT family protein YP_001922283.1 3086326 R 508767 CDS YP_001922284.1 188590185 6319086 3087321..3088001 1 NC_010723.1 hypothetical protein 3088001 6319086 CLH_2907 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922284.1 3087321 D 508767 CDS YP_001922285.1 188589872 6317601 3088048..3089013 1 NC_010723.1 identified by match to protein family HMM PF00015; putative methyl-accepting chemotaxis protein 3089013 6317601 CLH_2908 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis protein YP_001922285.1 3088048 D 508767 CDS YP_001922286.1 188589391 6320103 complement(3089211..3091304) 1 NC_010723.1 identified by match to protein family HMM PF01471; spore cortex-lytic protein 3091304 6320103 CLH_2909 Clostridium botulinum E3 str. Alaska E43 spore cortex-lytic protein YP_001922286.1 3089211 R 508767 CDS YP_001922287.1 188588852 6318536 complement(3091600..3092292) 1 NC_010723.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 3092292 6318536 CLH_2910 Clostridium botulinum E3 str. Alaska E43 Ser/Thr protein phosphatase family protein YP_001922287.1 3091600 R 508767 CDS YP_001922288.1 188588297 6318945 complement(3092323..3092583) 1 NC_010723.1 flagella-associated protein 3092583 6318945 CLH_2911 Clostridium botulinum E3 str. Alaska E43 flagella-associated protein YP_001922288.1 3092323 R 508767 CDS YP_001922289.1 188590639 6319910 complement(3092631..3094514) 1 NC_010723.1 hypothetical protein 3094514 6319910 CLH_2912 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922289.1 3092631 R 508767 CDS YP_001922290.1 188590186 6317921 complement(3094975..3096195) 1 NC_010723.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 3096195 tyrS 6317921 tyrS Clostridium botulinum E3 str. Alaska E43 tyrosyl-tRNA synthetase YP_001922290.1 3094975 R 508767 CDS YP_001922291.1 188589268 6317603 complement(3096524..3097642) 1 NC_010723.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887; spore germination protein 3097642 6317603 CLH_2914 Clostridium botulinum E3 str. Alaska E43 spore germination protein YP_001922291.1 3096524 R 508767 CDS YP_001922292.1 188588686 6318706 complement(3097632..3099038) 1 NC_010723.1 identified by match to protein family HMM PF03323; spore germination protein 3099038 6318706 CLH_2915 Clostridium botulinum E3 str. Alaska E43 spore germination protein YP_001922292.1 3097632 R 508767 CDS YP_001922293.1 188587752 6319194 3099218..3100315 1 NC_010723.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912; spore germination protein 3100315 6319194 CLH_2916 Clostridium botulinum E3 str. Alaska E43 spore germination protein YP_001922293.1 3099218 D 508767 CDS YP_001922294.1 188590648 6319318 complement(3100596..3101144) 1 NC_010723.1 membrane spanning protein 3101144 6319318 CLH_2917 Clostridium botulinum E3 str. Alaska E43 membrane spanning protein YP_001922294.1 3100596 R 508767 CDS YP_001922295.1 188589962 6319261 3101413..3102423 1 NC_010723.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3102423 trpS 6319261 trpS Clostridium botulinum E3 str. Alaska E43 tryptophanyl-tRNA synthetase YP_001922295.1 3101413 D 508767 CDS YP_001922296.1 188589023 6319033 complement(3102644..3104656) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; putative membrane-associated methyl-accepting chemotaxis protein fused to hamp domain 3104656 6319033 CLH_2919 Clostridium botulinum E3 str. Alaska E43 putative membrane-associated methyl-accepting chemotaxis protein fused to hamp domain YP_001922296.1 3102644 R 508767 CDS YP_001922297.1 188589656 6319074 complement(3104646..3104765) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3104765 6319074 CLH_2920 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922297.1 3104646 R 508767 CDS YP_001922298.1 188589208 6320386 complement(3104915..3105787) 1 NC_010723.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 3105787 galU 6320386 galU Clostridium botulinum E3 str. Alaska E43 UTP-glucose-1-phosphate uridylyltransferase YP_001922298.1 3104915 R 508767 CDS YP_001922299.1 188588193 6317633 3106132..3107403 1 NC_010723.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 3107403 brnQ 6317633 brnQ Clostridium botulinum E3 str. Alaska E43 branched-chain amino acid transport system II carrier protein YP_001922299.1 3106132 D 508767 CDS YP_001922300.1 188587845 6318071 complement(3107582..3108685) 1 NC_010723.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; lipopolysaccharide biosynthesis protein 3108685 6318071 CLH_2923 Clostridium botulinum E3 str. Alaska E43 lipopolysaccharide biosynthesis protein YP_001922300.1 3107582 R 508767 CDS YP_001922301.1 188588611 6317624 complement(3108913..3109518) 1 NC_010723.1 identified by match to protein family HMM PF02397; sugar transferase 3109518 pglB 6317624 pglB Clostridium botulinum E3 str. Alaska E43 sugar transferase YP_001922301.1 3108913 R 508767 CDS YP_001922302.1 188589785 6318035 complement(3109664..3110890) 1 NC_010723.1 identified by match to protein family HMM PF00534; WblI protein 3110890 6318035 CLH_2925 Clostridium botulinum E3 str. Alaska E43 WblI protein YP_001922302.1 3109664 R 508767 CDS YP_001922303.1 188590487 6320472 complement(3111235..3112482) 1 NC_010723.1 identified by match to protein family HMM PF00534; amylovoran biosynthesis AmsK 3112482 6320472 CLH_2926 Clostridium botulinum E3 str. Alaska E43 amylovoran biosynthesis AmsK YP_001922303.1 3111235 R 508767 CDS YP_001922304.1 188589764 6320519 3112698..3113762 1 NC_010723.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 3113762 6320519 CLH_2927 Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylglucosamine 2-epimerase YP_001922304.1 3112698 D 508767 CDS YP_001922305.1 188590507 6320121 complement(3113804..3115294) 1 NC_010723.1 hypothetical protein 3115294 6320121 CLH_2928 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922305.1 3113804 R 508767 CDS YP_001922306.1 188589357 6320602 complement(3115297..3117159) 1 NC_010723.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; Cap5D 3117159 6320602 CLH_2929 Clostridium botulinum E3 str. Alaska E43 Cap5D YP_001922306.1 3115297 R 508767 CDS YP_001922307.1 188589853 6317919 complement(3117224..3118207) 1 NC_010723.1 identified by match to protein family HMM PF00535; cell wall biosynthesis glycosyltransferase 3118207 6317919 CLH_2930 Clostridium botulinum E3 str. Alaska E43 cell wall biosynthesis glycosyltransferase YP_001922307.1 3117224 R 508767 CDS YP_001922308.1 188587855 6320094 complement(3118442..3119320) 1 NC_010723.1 identified by match to protein family HMM PF04991; LicD family protein 3119320 6320094 CLH_2931 Clostridium botulinum E3 str. Alaska E43 LicD family protein YP_001922308.1 3118442 R 508767 CDS YP_001922309.1 188588425 6319068 3119711..3120718 1 NC_010723.1 identified by match to protein family HMM PF00535; minor teichoic acid biosynthesis protein GgaB 3120718 6319068 CLH_2932 Clostridium botulinum E3 str. Alaska E43 minor teichoic acid biosynthesis protein GgaB YP_001922309.1 3119711 D 508767 CDS YP_001922310.1 188589841 6318901 complement(3121016..3121927) 1 NC_010723.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 3121927 6318901 CLH_2933 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter permease YP_001922310.1 3121016 R 508767 CDS YP_001922311.1 188590752 6320127 complement(3122187..3123074) 1 NC_010723.1 identified by match to protein family HMM PF00528; ABC transporter permease 3123074 6320127 CLH_2934 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001922311.1 3122187 R 508767 CDS YP_001922312.1 188588760 6320345 complement(3123336..3124655) 1 NC_010723.1 identified by match to protein family HMM PF01547; putative glycerol-3-phosphate ABC transporter 3124655 6320345 CLH_2935 Clostridium botulinum E3 str. Alaska E43 putative glycerol-3-phosphate ABC transporter YP_001922312.1 3123336 R 508767 CDS YP_001922313.1 188588823 6318980 complement(3124844..3125710) 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hydrolase, Cof family 3125710 6318980 CLH_2936 Clostridium botulinum E3 str. Alaska E43 hydrolase, Cof family YP_001922313.1 3124844 R 508767 CDS YP_001922314.1 188589344 6318714 complement(3125764..3127770) 1 NC_010723.1 identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; putative signaling protein 3127770 6318714 CLH_2937 Clostridium botulinum E3 str. Alaska E43 putative signaling protein YP_001922314.1 3125764 R 508767 CDS YP_001922315.1 188590047 6318206 complement(3128333..3129304) 1 NC_010723.1 identified by match to protein family HMM PF00892; integral membrane protein domain-containing protein 3129304 6318206 CLH_2938 Clostridium botulinum E3 str. Alaska E43 integral membrane protein domain-containing protein YP_001922315.1 3128333 R 508767 CDS YP_001922316.1 188590756 6317580 complement(3129846..3130553) 1 NC_010723.1 identified by match to protein family HMM PF01473; cell wall binding domain-containing protein 3130553 6317580 CLH_2939 Clostridium botulinum E3 str. Alaska E43 cell wall binding domain-containing protein YP_001922316.1 3129846 R 508767 CDS YP_001922317.1 188588176 6319117 complement(3130939..3132405) 1 NC_010723.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023; polysaccharide biosynthesis protein 3132405 6319117 CLH_2940 Clostridium botulinum E3 str. Alaska E43 polysaccharide biosynthesis protein YP_001922317.1 3130939 R 508767 CDS YP_001922318.1 188588875 6319398 complement(3132589..3133287) 1 NC_010723.1 LicC protein 3133287 6319398 CLH_2941 Clostridium botulinum E3 str. Alaska E43 LicC protein YP_001922318.1 3132589 R 508767 CDS YP_001922319.1 188589543 6318266 complement(3133302..3135161) 1 NC_010723.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01633; match to protein family HMM PF01636; choline/ethanolamine kinase family protein 3135161 6318266 CLH_2942 Clostridium botulinum E3 str. Alaska E43 choline/ethanolamine kinase family protein YP_001922319.1 3133302 R 508767 CDS YP_001922320.1 188589963 6317935 complement(3135869..3136414) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3136414 6317935 CLH_2943 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922320.1 3135869 R 508767 CDS YP_001922321.1 188589248 6318317 complement(3136782..3137405) 1 NC_010723.1 hypothetical protein 3137405 6318317 CLH_2944 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922321.1 3136782 R 508767 CDS YP_001922322.1 188588476 6317684 complement(3137701..3140685) 1 NC_010723.1 identified by match to protein family HMM PF01473; putative collagenolytic protease 3140685 6317684 CLH_2945 Clostridium botulinum E3 str. Alaska E43 putative collagenolytic protease YP_001922322.1 3137701 R 508767 CDS YP_001922323.1 188587653 6319276 complement(3141134..3143191) 1 NC_010723.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01520; surface protein PspC 3143191 6319276 CLH_2946 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922323.1 3141134 R 508767 CDS YP_001922324.1 188590597 6319328 complement(3143492..3145705) 1 NC_010723.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01520; surface protein PspC 3145705 6319328 CLH_2947 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922324.1 3143492 R 508767 CDS YP_001922325.1 188589654 6320329 3146051..3146320 1 NC_010723.1 putative anaerobic ribonucleoside-triphosphate reductase 3146320 6320329 CLH_2948 Clostridium botulinum E3 str. Alaska E43 putative anaerobic ribonucleoside-triphosphate reductase YP_001922325.1 3146051 D 508767 CDS YP_001922326.1 188589532 6320113 3146575..3147402 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YidA 3147402 6320113 CLH_2949 Clostridium botulinum E3 str. Alaska E43 phosphatase YidA YP_001922326.1 3146575 D 508767 CDS YP_001922327.1 188588772 6320301 3147705..3148535 1 NC_010723.1 identified by match to protein family HMM PF08543; pyridoxine kinase 3148535 6320301 CLH_2950 Clostridium botulinum E3 str. Alaska E43 pyridoxine kinase YP_001922327.1 3147705 D 508767 CDS YP_001922328.1 188587612 6319052 complement(3148670..3148981) 1 NC_010723.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 3148981 trx 6319052 trx Clostridium botulinum E3 str. Alaska E43 thioredoxin YP_001922328.1 3148670 R 508767 CDS YP_001922329.1 188588150 6319451 complement(3149092..3149958) 1 NC_010723.1 identified by match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase 3149958 6319451 CLH_2952 Clostridium botulinum E3 str. Alaska E43 pyridine nucleotide-disulfide oxidoreductase YP_001922329.1 3149092 R 508767 CDS YP_001922330.1 188590530 6319155 3150467..3151264 1 NC_010723.1 identified by match to protein family HMM PF02811; match to protein family HMM TIGR01856; HisJ family histidinol phosphate phosphatase 3151264 6319155 CLH_2953 Clostridium botulinum E3 str. Alaska E43 HisJ family histidinol phosphate phosphatase YP_001922330.1 3150467 D 508767 CDS YP_001922331.1 188589774 6319123 complement(3151478..3153532) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; membrane assosiated methyl-accepting chemotaxis protein with hamp domain 3153532 6319123 CLH_2954 Clostridium botulinum E3 str. Alaska E43 membrane assosiated methyl-accepting chemotaxis protein with hamp domain YP_001922331.1 3151478 R 508767 CDS YP_001922332.1 188588739 6318088 complement(3153898..3155937) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; putative methyl-accepting chemotaxis protein 3155937 6318088 CLH_2955 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis protein YP_001922332.1 3153898 R 508767 CDS YP_001922333.1 188587849 6317437 complement(3156560..3157951) 1 NC_010723.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 3157951 gltA 6317437 gltA Clostridium botulinum E3 str. Alaska E43 putative oxidoreductase YP_001922333.1 3156560 R 508767 CDS YP_001922334.1 188588577 6319085 complement(3157951..3158841) 1 NC_010723.1 identified by match to protein family HMM PF00175; ferredoxin-NADP(+) reductase subunit alpha 3158841 6319085 CLH_2957 Clostridium botulinum E3 str. Alaska E43 ferredoxin-NADP(+) reductase subunit alpha YP_001922334.1 3157951 R 508767 CDS YP_001922335.1 188587617 6320592 complement(3159096..3160262) 1 NC_010723.1 identified by match to protein family HMM PF00465; NADPH-dependent butanol dehydrogenase 3160262 6320592 CLH_2958 Clostridium botulinum E3 str. Alaska E43 NADPH-dependent butanol dehydrogenase YP_001922335.1 3159096 R 508767 CDS YP_001922336.1 188588302 6320507 complement(3160681..3162591) 1 NC_010723.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; signal-transduction and transcriptional-control protein 3162591 6320507 CLH_2959 Clostridium botulinum E3 str. Alaska E43 signal-transduction and transcriptional-control protein YP_001922336.1 3160681 R 508767 CDS YP_001922337.1 188590417 6319932 complement(3163008..3163451) 1 NC_010723.1 identified by match to protein family HMM PF06725; 3D domain-containing protein 3163451 6319932 CLH_2960 Clostridium botulinum E3 str. Alaska E43 3D domain-containing protein YP_001922337.1 3163008 R 508767 CDS YP_001922338.1 188589892 6318543 complement(3163734..3164174) 1 NC_010723.1 hypothetical protein 3164174 6318543 CLH_2961 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922338.1 3163734 R 508767 CDS YP_001922339.1 188588505 6318546 complement(3164606..3166201) 1 NC_010723.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR00503; peptide chain release factor 3 3166201 prfC 6318546 prfC Clostridium botulinum E3 str. Alaska E43 peptide chain release factor 3 YP_001922339.1 3164606 R 508767 CDS YP_001922340.1 188588602 6318204 complement(3166744..3170958) 1 NC_010723.1 identified by match to protein family HMM PF01473; match to protein family HMM PF09479; match to protein family HMM TIGR02543; putative cell wall binding repeat protein 3170958 6318204 CLH_2963 Clostridium botulinum E3 str. Alaska E43 putative cell wall binding repeat protein YP_001922340.1 3166744 R 508767 CDS YP_001922341.1 188587890 6318164 complement(3171055..3171639) 1 NC_010723.1 hypothetical protein 3171639 6318164 CLH_2964 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922341.1 3171055 R 508767 CDS YP_001922342.1 188590037 6317349 complement(3172010..3174097) 1 NC_010723.1 identified by match to protein family HMM PF00990; match to protein family HMM PF07719; match to protein family HMM TIGR00254; putative ggdef domain-containing protein 3174097 6317349 CLH_2965 Clostridium botulinum E3 str. Alaska E43 putative ggdef domain-containing protein YP_001922342.1 3172010 R 508767 CDS YP_001922343.1 188589356 6319410 complement(3174141..3175574) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3175574 6319410 CLH_2966 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922343.1 3174141 R 508767 CDS YP_001922344.1 188590790 6317918 complement(3176131..3177369) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3177369 6317918 CLH_2967 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922344.1 3176131 R 508767 CDS YP_001922345.1 188589783 6319290 complement(3177520..3178866) 1 NC_010723.1 identified by match to protein family HMM PF01473; collagenolytic protease 3178866 6319290 CLH_2968 Clostridium botulinum E3 str. Alaska E43 collagenolytic protease YP_001922345.1 3177520 R 508767 CDS YP_001922346.1 188590116 6318280 complement(3179027..3179902) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3179902 6318280 CLH_2969 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922346.1 3179027 R 508767 CDS YP_001922347.1 188588352 6317831 complement(3180188..3181792) 1 NC_010723.1 identified by match to protein family HMM PF01473; collagenolytic protease 3181792 6317831 CLH_2970 Clostridium botulinum E3 str. Alaska E43 collagenolytic protease YP_001922347.1 3180188 R 508767 CDS YP_001922348.1 188588671 6318891 complement(3182127..3183839) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; membrane assosiated methyl-accepting chemotaxis protein with hamp domain 3183839 6318891 CLH_2971 Clostridium botulinum E3 str. Alaska E43 membrane assosiated methyl-accepting chemotaxis protein with hamp domain YP_001922348.1 3182127 R 508767 CDS YP_001922349.1 188589171 6318075 complement(3184419..3184736) 1 NC_010723.1 identified by match to protein family HMM PF01473; collagenolytic protease 3184736 6318075 CLH_2972 Clostridium botulinum E3 str. Alaska E43 collagenolytic protease YP_001922349.1 3184419 R 508767 CDS YP_001922350.1 188588839 6318044 complement(3185065..3187569) 1 NC_010723.1 identified by match to protein family HMM PF00196; transcriptional regulator, LuxR family protein 3187569 6318044 CLH_2973 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, LuxR family protein YP_001922350.1 3185065 R 508767 CDS YP_001922351.1 188589415 6318258 complement(3187666..3189480) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3189480 6318258 CLH_2974 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922351.1 3187666 R 508767 CDS YP_001922352.1 188590676 6317568 complement(3190064..3192298) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3192298 6317568 CLH_2975 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922352.1 3190064 R 508767 CDS YP_001922353.1 188588129 6320247 complement(3192559..3194232) 1 NC_010723.1 identified by match to protein family HMM PF01473; collagenolytic protease 3194232 6320247 CLH_2976 Clostridium botulinum E3 str. Alaska E43 collagenolytic protease YP_001922353.1 3192559 R 508767 CDS YP_001922354.1 188588323 6319149 complement(3194620..3196926) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspA 3196926 6319149 CLH_2977 Clostridium botulinum E3 str. Alaska E43 surface protein PspA YP_001922354.1 3194620 R 508767 CDS YP_001922355.1 188589075 6319966 complement(3197170..3198954) 1 NC_010723.1 identified by match to protein family HMM PF01473; hypothetical protein 3198954 6319966 CLH_2978 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922355.1 3197170 R 508767 CDS YP_001922356.1 188590285 6318896 3199513..3200994 1 NC_010723.1 putative lipoprotein 3200994 6318896 CLH_2979 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001922356.1 3199513 D 508767 CDS YP_001922357.1 188589559 6320599 complement(3201103..3203142) 1 NC_010723.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649; neutral endopeptidase 3203142 6320599 CLH_2980 Clostridium botulinum E3 str. Alaska E43 neutral endopeptidase YP_001922357.1 3201103 R 508767 CDS YP_001922358.1 188588828 6318193 complement(3203594..3204088) 1 NC_010723.1 hypothetical protein 3204088 6318193 CLH_2981 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922358.1 3203594 R 508767 CDS YP_001922359.1 188588104 6318143 complement(3204081..3204596) 1 NC_010723.1 hypothetical protein 3204596 6318143 CLH_2982 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922359.1 3204081 R 508767 CDS YP_001922360.1 188588387 6317972 3204590..3204739 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3204739 6317972 CLH_2983 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922360.1 3204590 D 508767 CDS YP_001922361.1 188589341 6319976 complement(3204922..3205656) 1 NC_010723.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01714; phage protein 3205656 6319976 CLH_2984 Clostridium botulinum E3 str. Alaska E43 phage protein YP_001922361.1 3204922 R 508767 CDS YP_001922362.1 188588173 6317817 complement(3205898..3206746) 1 NC_010723.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 3206746 6317817 CLH_2985 Clostridium botulinum E3 str. Alaska E43 glycosyl transferase family protein YP_001922362.1 3205898 R 508767 CDS YP_001922363.1 188589116 6319457 3206866..3207699 1 NC_010723.1 hypothetical protein 3207699 6319457 CLH_2986 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922363.1 3206866 D 508767 CDS YP_001922364.1 188587831 6320555 complement(3207787..3208017) 1 NC_010723.1 acyl carrier protein 3208017 6320555 CLH_2987 Clostridium botulinum E3 str. Alaska E43 acyl carrier protein YP_001922364.1 3207787 R 508767 CDS YP_001922365.1 188590146 6317404 complement(3208064..3209578) 1 NC_010723.1 identified by match to protein family HMM PF00501; amino acid adenylation protein 3209578 6317404 CLH_2988 Clostridium botulinum E3 str. Alaska E43 amino acid adenylation protein YP_001922365.1 3208064 R 508767 CDS YP_001922366.1 188590223 6317642 complement(3209599..3210957) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3210957 6317642 CLH_2989 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922366.1 3209599 R 508767 CDS YP_001922367.1 188589513 6320455 complement(3210944..3212542) 1 NC_010723.1 identified by match to protein family HMM PF03062; alginate O-acetylation protein 3212542 6320455 CLH_2990 Clostridium botulinum E3 str. Alaska E43 alginate O-acetylation protein YP_001922367.1 3210944 R 508767 CDS YP_001922368.1 188589742 6317822 complement(3213554..3213775) 1 NC_010723.1 transposase, IS4 family protein 3213775 6317822 CLH_2991 Clostridium botulinum E3 str. Alaska E43 transposase, IS4 family protein YP_001922368.1 3213554 R 508767 CDS YP_001922369.1 188589021 6319706 complement(3213739..3213906) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3213906 6319706 CLH_2992 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922369.1 3213739 R 508767 CDS YP_001922370.1 188590714 6317648 complement(3214165..3215022) 1 NC_010723.1 identified by match to protein family HMM PF00535; family 2 glycosyl transferase 3215022 6317648 CLH_2993 Clostridium botulinum E3 str. Alaska E43 family 2 glycosyl transferase YP_001922370.1 3214165 R 508767 CDS YP_001922371.1 188589993 6319296 complement(3215027..3216175) 1 NC_010723.1 identified by match to protein family HMM PF04464; glycosyl transferase family protein 3216175 6319296 CLH_2994 Clostridium botulinum E3 str. Alaska E43 glycosyl transferase family protein YP_001922371.1 3215027 R 508767 CDS YP_001922372.1 188588392 6318974 complement(3216176..3217201) 1 NC_010723.1 identified by match to protein family HMM PF08240; zinc-dependent alcohol dehydrogenase 3217201 6318974 CLH_2995 Clostridium botulinum E3 str. Alaska E43 zinc-dependent alcohol dehydrogenase YP_001922372.1 3216176 R 508767 CDS YP_001922373.1 188587800 6319830 complement(3217191..3217910) 1 NC_010723.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3217910 ispD 6319830 ispD Clostridium botulinum E3 str. Alaska E43 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001922373.1 3217191 R 508767 CDS YP_001922374.1 188588769 6317890 complement(3217936..3219189) 1 NC_010723.1 identified by match to protein family HMM PF04464; putative CDP-glycerol:glycerophosphate glycerophosphotransferase 3219189 6317890 CLH_2997 Clostridium botulinum E3 str. Alaska E43 putative CDP-glycerol:glycerophosphate glycerophosphotransferase YP_001922374.1 3217936 R 508767 CDS YP_001922375.1 188588055 6318489 complement(3219236..3219970) 1 NC_010723.1 identified by match to protein family HMM PF00005; teichoic acids export ATP-binding protein TagH 3219970 6318489 CLH_2998 Clostridium botulinum E3 str. Alaska E43 teichoic acids export ATP-binding protein TagH YP_001922375.1 3219236 R 508767 CDS YP_001922376.1 188588961 6319114 complement(3219982..3220758) 1 NC_010723.1 identified by match to protein family HMM PF01061; ABC transporter 3220758 6319114 CLH_2999 Clostridium botulinum E3 str. Alaska E43 ABC transporter YP_001922376.1 3219982 R 508767 CDS YP_001922377.1 188588264 6317519 complement(3220778..3221632) 1 NC_010723.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214; dTDP-4-dehydrorhamnose reductase 3221632 rfbD 6317519 rfbD Clostridium botulinum E3 str. Alaska E43 dTDP-4-dehydrorhamnose reductase YP_001922377.1 3220778 R 508767 CDS YP_001922378.1 188590488 6319858 complement(3221653..3222630) 1 NC_010723.1 identified by match to protein family HMM PF00535; glycosyltransferase 3222630 6319858 CLH_3001 Clostridium botulinum E3 str. Alaska E43 glycosyltransferase YP_001922378.1 3221653 R 508767 CDS YP_001922379.1 188589709 6320520 complement(3222725..3223744) 1 NC_010723.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 3223744 rfbB 6320520 rfbB Clostridium botulinum E3 str. Alaska E43 dTDP-glucose 4,6-dehydratase YP_001922379.1 3222725 R 508767 CDS YP_001922380.1 188588490 6318282 complement(3223858..3224397) 1 NC_010723.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221; dTDP-4-dehydrorhamnose 3,5-epimerase 3224397 rfbC 6318282 rfbC Clostridium botulinum E3 str. Alaska E43 dTDP-4-dehydrorhamnose 3,5-epimerase YP_001922380.1 3223858 R 508767 CDS YP_001922381.1 188587794 6320383 complement(3224429..3225307) 1 NC_010723.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 3225307 rfbA 6320383 rfbA Clostridium botulinum E3 str. Alaska E43 glucose-1-phosphate thymidylyltransferase YP_001922381.1 3224429 R 508767 CDS YP_001922382.1 188589979 6317799 3225576..3227015 1 NC_010723.1 identified by match to protein family HMM PF02397; match to protein family HMM TIGR03023; match to protein family HMM TIGR03025; undecaprenyl-phosphate glucose phosphotransferase 3227015 6317799 CLH_3005 Clostridium botulinum E3 str. Alaska E43 undecaprenyl-phosphate glucose phosphotransferase YP_001922382.1 3225576 D 508767 CDS YP_001922383.1 188589273 6318335 complement(3227328..3227474) 1 NC_010723.1 hypothetical protein 3227474 6318335 CLH_3006 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922383.1 3227328 R 508767 CDS YP_001922384.1 188588119 6317818 3228041..3229873 1 NC_010723.1 identified by match to protein family HMM PF04932; O-antigen polymerase family 3229873 6317818 CLH_3007 Clostridium botulinum E3 str. Alaska E43 O-antigen polymerase family YP_001922384.1 3228041 D 508767 CDS YP_001922385.1 188590688 6318874 complement(3229979..3230386) 1 NC_010723.1 identified by match to protein family HMM PF01934; hypothetical protein 3230386 6318874 CLH_3008 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922385.1 3229979 R 508767 CDS YP_001922386.1 188589705 6317870 complement(3230376..3230777) 1 NC_010723.1 identified by match to protein family HMM PF01909; DNA polymerase, beta domain-containing protein region 3230777 6317870 CLH_3009 Clostridium botulinum E3 str. Alaska E43 DNA polymerase, beta domain-containing protein region YP_001922386.1 3230376 R 508767 CDS YP_001922387.1 188590403 6317332 complement(3230965..3232752) 1 NC_010723.1 identified by match to protein family HMM PF01473; SigA binding protein 3232752 6317332 CLH_3010 Clostridium botulinum E3 str. Alaska E43 SigA binding protein YP_001922387.1 3230965 R 508767 CDS YP_001922388.1 188588203 6320038 complement(3233454..3235775) 1 NC_010723.1 identified by match to protein family HMM PF01473; SigA binding protein 3235775 6320038 CLH_3011 Clostridium botulinum E3 str. Alaska E43 SigA binding protein YP_001922388.1 3233454 R 508767 CDS YP_001922389.1 188588949 6319514 3237328..3237579 1 NC_010723.1 hypothetical protein 3237579 6319514 CLH_3012 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922389.1 3237328 D 508767 CDS YP_001922390.1 188588982 6318268 complement(3237864..3239978) 1 NC_010723.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01473; putative surface protein C 3239978 6318268 CLH_3013 Clostridium botulinum E3 str. Alaska E43 putative surface protein C YP_001922390.1 3237864 R 508767 CDS YP_001922391.1 188589903 6320391 complement(3240312..3241157) 1 NC_010723.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 3241157 6320391 CLH_3014 Clostridium botulinum E3 str. Alaska E43 putative L-xylulose 5-phosphate 3-epimerase YP_001922391.1 3240312 R 508767 CDS YP_001922392.1 188587594 6320353 complement(3241355..3242044) 1 NC_010723.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3242044 araD 6320353 araD Clostridium botulinum E3 str. Alaska E43 L-ribulose-5-phosphate 4-epimerase YP_001922392.1 3241355 R 508767 CDS YP_001922393.1 188588480 6319645 complement(3242401..3243438) 1 NC_010723.1 hypothetical protein 3243438 6319645 CLH_3016 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922393.1 3242401 R 508767 CDS YP_001922394.1 188588756 6319924 complement(3243577..3243870) 1 NC_010723.1 identified by match to protein family HMM PF02302; PTS system enzyme IIB component 3243870 6319924 CLH_3017 Clostridium botulinum E3 str. Alaska E43 PTS system enzyme IIB component YP_001922394.1 3243577 R 508767 CDS YP_001922395.1 188589189 6317783 complement(3243949..3245403) 1 NC_010723.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 3245403 6317783 CLH_3018 Clostridium botulinum E3 str. Alaska E43 PTS system ascorbate-specific transporter subunit IIC YP_001922395.1 3243949 R 508767 CDS YP_001922396.1 188588064 6317564 complement(3245496..3245939) 1 NC_010723.1 identified by match to protein family HMM PF00359; phosphotransferase system mannitol/fructose-specific IIA domain 3245939 6317564 CLH_3019 Clostridium botulinum E3 str. Alaska E43 phosphotransferase system mannitol/fructose-specific IIA domain YP_001922396.1 3245496 R 508767 CDS YP_001922397.1 188588544 6319044 complement(3246080..3247144) 1 NC_010723.1 putative L-ascorbate 6-phosphate lactonase 3247144 6319044 CLH_3020 Clostridium botulinum E3 str. Alaska E43 putative L-ascorbate 6-phosphate lactonase YP_001922397.1 3246080 R 508767 CDS YP_001922398.1 188589518 6318942 3247455..3248246 1 NC_010723.1 identified by match to protein family HMM PF00455; match to protein family HMM PF01022; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 3248246 6318942 CLH_3021 Clostridium botulinum E3 str. Alaska E43 DeoR family transcriptional regulator YP_001922398.1 3247455 D 508767 CDS YP_001922399.1 188589279 6320277 complement(3248452..3249741) 1 NC_010723.1 catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 2 3249741 6320277 CLH_3022 Clostridium botulinum E3 str. Alaska E43 putative aminopeptidase 2 YP_001922399.1 3248452 R 508767 CDS YP_001922400.1 188590173 6317596 3250491..3251666 1 NC_010723.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 3251666 6317596 CLH_3023 Clostridium botulinum E3 str. Alaska E43 cation efflux family protein YP_001922400.1 3250491 D 508767 CDS YP_001922401.1 188588985 6318341 3251951..3252274 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3252274 6318341 CLH_3024 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922401.1 3251951 D 508767 CDS YP_001922402.1 188589985 6318336 complement(3253008..3254639) 1 NC_010723.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; putative acetolactate synthase large subunit 3254639 6318336 CLH_3025 Clostridium botulinum E3 str. Alaska E43 putative acetolactate synthase large subunit YP_001922402.1 3253008 R 508767 CDS YP_001922403.1 188589022 6318187 complement(3254626..3255087) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3255087 6318187 CLH_3026 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922403.1 3254626 R 508767 CDS YP_001922404.1 188588343 6319073 complement(3255542..3255913) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3255913 6319073 CLH_3027 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922404.1 3255542 R 508767 CDS YP_001922405.1 188589540 6318377 complement(3256109..3256480) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3256480 6318377 CLH_3028 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922405.1 3256109 R 508767 CDS YP_001922406.1 188588239 6320159 3256850..3257500 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3257500 6320159 CLH_3029 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922406.1 3256850 D 508767 CDS YP_001922407.1 188588563 6319603 complement(3257651..3259117) 1 NC_010723.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 3259117 6319603 CLH_3030 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001922407.1 3257651 R 508767 CDS YP_001922408.1 188589494 6318201 complement(3259479..3260201) 1 NC_010723.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 3260201 6318201 CLH_3031 Clostridium botulinum E3 str. Alaska E43 glutamine transport ATP-binding protein GlnQ YP_001922408.1 3259479 R 508767 CDS YP_001922409.1 188589667 6318723 complement(3260188..3260847) 1 NC_010723.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter substrate-binding protein/permease 3260847 6318723 CLH_3032 Clostridium botulinum E3 str. Alaska E43 amino acid ABC transporter substrate-binding protein/permease YP_001922409.1 3260188 R 508767 CDS YP_001922410.1 188590550 6320134 complement(3260929..3261765) 1 NC_010723.1 identified by match to protein family HMM PF00497; amino acid ABC transporter 3261765 6320134 CLH_3033 Clostridium botulinum E3 str. Alaska E43 amino acid ABC transporter YP_001922410.1 3260929 R 508767 CDS YP_001922411.1 188588010 6318814 complement(3262445..3264556) 1 NC_010723.1 ATP-dependent DNA helicase rep 3264556 6318814 CLH_3034 Clostridium botulinum E3 str. Alaska E43 ATP-dependent DNA helicase rep YP_001922411.1 3262445 R 508767 CDS YP_001922412.1 188588998 6319529 complement(3264907..3267003) 1 NC_010723.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; putative cell division protease FtsH 3267003 6319529 CLH_3035 Clostridium botulinum E3 str. Alaska E43 putative cell division protease FtsH YP_001922412.1 3264907 R 508767 CDS YP_001922413.1 188588253 6319698 complement(3267048..3267266) 1 NC_010723.1 hypothetical protein 3267266 6319698 CLH_3036 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922413.1 3267048 R 508767 CDS YP_001922414.1 188588989 6319716 complement(3267401..3267928) 1 NC_010723.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 3267928 lepB 6319716 lepB Clostridium botulinum E3 str. Alaska E43 signal peptidase I YP_001922414.1 3267401 R 508767 CDS YP_001922415.1 188589335 6319305 complement(3267995..3268513) 1 NC_010723.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 3268513 lepB 6319305 lepB Clostridium botulinum E3 str. Alaska E43 signal peptidase I YP_001922415.1 3267995 R 508767 CDS YP_001922416.1 188588479 6318441 complement(3268799..3270094) 1 NC_010723.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase 3270094 lysA 6318441 lysA Clostridium botulinum E3 str. Alaska E43 diaminopimelate decarboxylase YP_001922416.1 3268799 R 508767 CDS YP_001922417.1 188589959 6319923 complement(3270411..3270524) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3270524 6319923 CLH_3040 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922417.1 3270411 R 508767 CDS YP_001922418.1 188590491 6317883 complement(3270675..3271349) 1 NC_010723.1 dihydrodipicolinate synthase/N-acetylneuraminate lyase 3271349 6317883 CLH_3041 Clostridium botulinum E3 str. Alaska E43 dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_001922418.1 3270675 R 508767 CDS YP_001922419.1 188587604 6318829 complement(3271446..3271577) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3271577 6318829 CLH_3042 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922419.1 3271446 R 508767 CDS YP_001922420.1 188588463 6319853 complement(3272182..3272943) 1 NC_010723.1 identified by match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase 3272943 6319853 CLH_3043 Clostridium botulinum E3 str. Alaska E43 N-acetylmuramoyl-L-alanine amidase YP_001922420.1 3272182 R 508767 CDS YP_001922421.1 188589832 6319873 complement(3273096..3274340) 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; membrane associated methyl-accepting chemotaxis protein 3274340 6319873 CLH_3044 Clostridium botulinum E3 str. Alaska E43 membrane associated methyl-accepting chemotaxis protein YP_001922421.1 3273096 R 508767 CDS YP_001922422.1 188590740 6319673 3274577..3275761 1 NC_010723.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 3275761 6319673 CLH_3045 Clostridium botulinum E3 str. Alaska E43 aspartate aminotransferase YP_001922422.1 3274577 D 508767 CDS YP_001922423.1 188590759 6317964 complement(3275860..3278814) 1 NC_010723.1 identified by match to protein family HMM PF00092; von Willebrand factor type A domain-containing protein 3278814 6317964 CLH_3046 Clostridium botulinum E3 str. Alaska E43 von Willebrand factor type A domain-containing protein YP_001922423.1 3275860 R 508767 CDS YP_001922424.1 188588509 6318178 complement(3278891..3279427) 1 NC_010723.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; putative prepilin peptidase-dependent 3279427 6318178 CLH_3047 Clostridium botulinum E3 str. Alaska E43 putative prepilin peptidase-dependent YP_001922424.1 3278891 R 508767 CDS YP_001922425.1 188589252 6318354 complement(3279444..3281816) 1 NC_010723.1 hypothetical protein 3281816 6318354 CLH_3048 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922425.1 3279444 R 508767 CDS YP_001922426.1 188590628 6317308 complement(3281828..3282745) 1 NC_010723.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; prokaryotic N- methylation motif domain-containing protein 3282745 6317308 CLH_3049 Clostridium botulinum E3 str. Alaska E43 prokaryotic N- methylation motif domain-containing protein YP_001922426.1 3281828 R 508767 CDS YP_001922427.1 188589910 6318508 complement(3282756..3284027) 1 NC_010723.1 hypothetical protein 3284027 6318508 CLH_3050 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922427.1 3282756 R 508767 CDS YP_001922428.1 188588799 6319575 complement(3284024..3284587) 1 NC_010723.1 identified by match to protein family HMM PF05137; fimbrial assembly protein PilN 3284587 6319575 CLH_3051 Clostridium botulinum E3 str. Alaska E43 fimbrial assembly protein PilN YP_001922428.1 3284024 R 508767 CDS YP_001922429.1 188588862 6319256 complement(3284603..3285769) 1 NC_010723.1 identified by match to protein family HMM TIGR01175; type IV pilus assembly protein PilM 3285769 6319256 CLH_3052 Clostridium botulinum E3 str. Alaska E43 type IV pilus assembly protein PilM YP_001922429.1 3284603 R 508767 CDS YP_001922430.1 188587966 6320063 complement(3286024..3286458) 1 NC_010723.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; prepilin peptidase-dependent 3286458 6320063 CLH_3053 Clostridium botulinum E3 str. Alaska E43 prepilin peptidase-dependent YP_001922430.1 3286024 R 508767 CDS YP_001922431.1 188590753 6317329 complement(3286481..3287683) 1 NC_010723.1 identified by match to protein family HMM PF00482; type II secretion system protein F 3287683 6317329 CLH_3054 Clostridium botulinum E3 str. Alaska E43 type II secretion system protein F YP_001922431.1 3286481 R 508767 CDS YP_001922432.1 188590152 6320346 complement(3287792..3289480) 1 NC_010723.1 identified by match to protein family HMM PF00437; match to protein family HMM PF05157; type IV pilus assembly protein TapB 3289480 6320346 CLH_3055 Clostridium botulinum E3 str. Alaska E43 type IV pilus assembly protein TapB YP_001922432.1 3287792 R 508767 CDS YP_001922433.1 188588741 6317762 complement(3289543..3290301) 1 NC_010723.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750; type IV leader peptidase family protein 3290301 6317762 CLH_3056 Clostridium botulinum E3 str. Alaska E43 type IV leader peptidase family protein YP_001922433.1 3289543 R 508767 CDS YP_001922434.1 188587692 6317394 complement(3290840..3291790) 1 NC_010723.1 putative lipoprotein 3291790 6317394 CLH_3057 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001922434.1 3290840 R 508767 CDS YP_001922435.1 188590599 6318748 complement(3292130..3292444) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3292444 6318748 CLH_3058 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922435.1 3292130 R 508767 CDS YP_001922436.1 188589708 6320331 3292849..3294729 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM TIGR01098; methyl-accepting chemotaxis protein 3294729 6320331 CLH_3059 Clostridium botulinum E3 str. Alaska E43 methyl-accepting chemotaxis protein YP_001922436.1 3292849 D 508767 CDS YP_001922437.1 188589197 6318431 complement(3295033..3295236) 1 NC_010723.1 identified by match to protein family HMM PF00403; copper-transporting P-type ATPase 3295236 6318431 CLH_3060 Clostridium botulinum E3 str. Alaska E43 copper-transporting P-type ATPase YP_001922437.1 3295033 R 508767 CDS YP_001922438.1 188590333 6318580 complement(3295399..3297828) 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-translocating P-type ATPase 3297828 6318580 CLH_3061 Clostridium botulinum E3 str. Alaska E43 copper-translocating P-type ATPase YP_001922438.1 3295399 R 508767 CDS YP_001922439.1 188588013 6317721 complement(3297885..3298151) 1 NC_010723.1 identified by match to protein family HMM PF02583; hypothetical protein 3298151 6317721 CLH_3062 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922439.1 3297885 R 508767 CDS YP_001922440.1 188588944 6317934 complement(3298502..3299680) 1 NC_010723.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; thermostable carboxypeptidase 1 3299680 6317934 CLH_3063 Clostridium botulinum E3 str. Alaska E43 thermostable carboxypeptidase 1 YP_001922440.1 3298502 R 508767 CDS YP_001922441.1 188589826 6318024 3299840..3300292 1 NC_010723.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; putative peroxiredoxin bcp 3300292 6318024 CLH_3064 Clostridium botulinum E3 str. Alaska E43 putative peroxiredoxin bcp YP_001922441.1 3299840 D 508767 CDS YP_001922442.1 188590722 6320426 complement(3300379..3301158) 1 NC_010723.1 identified by match to protein family HMM PF00795; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 3301158 6320426 CLH_3065 Clostridium botulinum E3 str. Alaska E43 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001922442.1 3300379 R 508767 CDS YP_001922443.1 188588728 6320296 complement(3301278..3304379) 1 NC_010723.1 identified by match to protein family HMM PF05031; putative cell wall anchor domain-containing protein 3304379 6320296 CLH_3066 Clostridium botulinum E3 str. Alaska E43 putative cell wall anchor domain-containing protein YP_001922443.1 3301278 R 508767 CDS YP_001922444.1 188589528 6320045 complement(3304446..3304892) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3304892 6320045 CLH_3067 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922444.1 3304446 R 508767 CDS YP_001922445.1 188588031 6318148 complement(3304918..3305298) 1 NC_010723.1 identified by match to protein family HMM PF04304; hypothetical protein 3305298 6318148 CLH_3068 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922445.1 3304918 R 508767 CDS YP_001922446.1 188588081 6319214 complement(3305341..3305607) 1 NC_010723.1 hypothetical protein 3305607 6319214 CLH_3069 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922446.1 3305341 R 508767 CDS YP_001922447.1 188589392 6319274 complement(3305865..3307550) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 3307550 6319274 CLH_3070 Clostridium botulinum E3 str. Alaska E43 ABC transporter ATP-binding/permease YP_001922447.1 3305865 R 508767 CDS YP_001922448.1 188588670 6318537 complement(3307554..3309305) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug resistance protein 1 3309305 6318537 CLH_3071 Clostridium botulinum E3 str. Alaska E43 multidrug resistance protein 1 YP_001922448.1 3307554 R 508767 CDS YP_001922449.1 188588446 6318074 complement(3309601..3311187) 1 NC_010723.1 lipase 3311187 6318074 CLH_3072 Clostridium botulinum E3 str. Alaska E43 lipase YP_001922449.1 3309601 R 508767 CDS YP_001922450.1 188587698 6319589 complement(3311287..3312627) 1 NC_010723.1 putative lipase 3312627 6319589 CLH_3073 Clostridium botulinum E3 str. Alaska E43 putative lipase YP_001922450.1 3311287 R 508767 CDS YP_001922451.1 188590654 6318949 complement(3313715..3315073) 1 NC_010723.1 lipase 2 3315073 6318949 CLH_3074 Clostridium botulinum E3 str. Alaska E43 lipase 2 YP_001922451.1 3313715 R 508767 CDS YP_001922452.1 188589935 6317981 complement(3315953..3316747) 1 NC_010723.1 membrane protein 3316747 6317981 CLH_3075 Clostridium botulinum E3 str. Alaska E43 membrane protein YP_001922452.1 3315953 R 508767 CDS YP_001922453.1 188590260 6319937 complement(3317078..3317842) 1 NC_010723.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; RNA pseudouridine synthase family protein 3317842 6319937 CLH_3076 Clostridium botulinum E3 str. Alaska E43 RNA pseudouridine synthase family protein YP_001922453.1 3317078 R 508767 CDS YP_001922454.1 188589556 6318048 complement(3317935..3318141) 1 NC_010723.1 transcription regulator, Cro/CI family -related protein 3318141 6318048 CLH_3077 Clostridium botulinum E3 str. Alaska E43 transcription regulator, Cro/CI family -related protein YP_001922454.1 3317935 R 508767 CDS YP_001922455.1 188588434 6318384 complement(3318160..3318654) 1 NC_010723.1 hypothetical protein 3318654 6318384 CLH_3078 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922455.1 3318160 R 508767 CDS YP_001922456.1 188587856 6320338 complement(3318818..3319033) 1 NC_010723.1 putative lipoprotein 3319033 6320338 CLH_3079 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001922456.1 3318818 R 508767 CDS YP_001922457.1 188588597 6319069 complement(3319432..3320250) 1 NC_010723.1 identified by match to protein family HMM PF00941; medium FAD-binding subunit of molybdenum enzyme 3320250 6319069 CLH_3080 Clostridium botulinum E3 str. Alaska E43 medium FAD-binding subunit of molybdenum enzyme YP_001922457.1 3319432 R 508767 CDS YP_001922458.1 188589328 6319234 complement(3320244..3320720) 1 NC_010723.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; putative xanthine dehydrogenase, iron-sulfur binding subunit 3320720 6319234 CLH_3081 Clostridium botulinum E3 str. Alaska E43 putative xanthine dehydrogenase, iron-sulfur binding subunit YP_001922458.1 3320244 R 508767 CDS YP_001922459.1 188589002 6318756 complement(3320722..3322851) 1 NC_010723.1 identified by match to protein family HMM PF01315; match to protein family HMM PF02738; putative xanthine dehydrogenase, molybdenum-binding subunit 3322851 6318756 CLH_3082 Clostridium botulinum E3 str. Alaska E43 putative xanthine dehydrogenase, molybdenum-binding subunit YP_001922459.1 3320722 R 508767 CDS YP_001922460.1 188589320 6319867 complement(3322973..3323899) 1 NC_010723.1 identified by match to protein family HMM PF00126; transcriptional regulator, LysR family protein 3323899 6319867 CLH_3083 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, LysR family protein YP_001922460.1 3322973 R 508767 CDS YP_001922461.1 188590211 6317659 complement(3324109..3325476) 1 NC_010723.1 identified by match to protein family HMM PF01938; match to protein family HMM PF02475; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 3325476 rumA 6317659 rumA Clostridium botulinum E3 str. Alaska E43 23S rRNA (uracil-5-)-methyltransferase RumA YP_001922461.1 3324109 R 508767 CDS YP_001922462.1 188587884 6317301 complement(3325707..3326063) 1 NC_010723.1 hypothetical protein 3326063 6317301 CLH_3085 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922462.1 3325707 R 508767 CDS YP_001922463.1 188589682 6319338 complement(3326418..3327833) 1 NC_010723.1 identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; pyruvate kinase 3327833 pyk 6319338 pyk Clostridium botulinum E3 str. Alaska E43 pyruvate kinase YP_001922463.1 3326418 R 508767 CDS YP_001922464.1 188590611 6319420 complement(3327893..3328855) 1 NC_010723.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 3328855 pfkA 6319420 pfkA Clostridium botulinum E3 str. Alaska E43 6-phosphofructokinase YP_001922464.1 3327893 R 508767 CDS YP_001922465.1 188588146 6318108 complement(3329381..3332989) 1 NC_010723.1 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 3332989 dnaE 6318108 dnaE Clostridium botulinum E3 str. Alaska E43 DNA polymerase III DnaE YP_001922465.1 3329381 R 508767 CDS YP_001922466.1 188587729 6318688 complement(3333601..3333885) 1 NC_010723.1 identified by match to protein family HMM PF07876; stress responsive alpha-beta barrel domain-containing protein 3333885 6318688 CLH_3089 Clostridium botulinum E3 str. Alaska E43 stress responsive alpha-beta barrel domain-containing protein YP_001922466.1 3333601 R 508767 CDS YP_001922467.1 188589712 6318668 complement(3333902..3334849) 1 NC_010723.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 3334849 6318668 CLH_3090 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922467.1 3333902 R 508767 CDS YP_001922468.1 188589167 6320403 complement(3334865..3336226) 1 NC_010723.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; transporter 3336226 6320403 CLH_3091 Clostridium botulinum E3 str. Alaska E43 transporter YP_001922468.1 3334865 R 508767 CDS YP_001922469.1 188589800 6319012 complement(3336223..3337107) 1 NC_010723.1 identified by match to protein family HMM PF03668; hypothetical protein 3337107 6319012 CLH_3092 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922469.1 3336223 R 508767 CDS YP_001922470.1 188589074 6320146 complement(3337538..3338452) 1 NC_010723.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 3338452 murB 6320146 murB Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001922470.1 3337538 R 508767 CDS YP_001922471.1 188587558 6318895 complement(3338525..3340414) 1 NC_010723.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 3340414 uvrC 6318895 uvrC Clostridium botulinum E3 str. Alaska E43 excinuclease ABC subunit C YP_001922471.1 3338525 R 508767 CDS YP_001922472.1 188590118 6319416 complement(3340630..3342114) 1 NC_010723.1 identified by match to protein family HMM PF00905; penicillin-binding protein 3342114 6319416 CLH_3095 Clostridium botulinum E3 str. Alaska E43 penicillin-binding protein YP_001922472.1 3340630 R 508767 CDS YP_001922473.1 188589430 6317266 complement(3342117..3343307) 1 NC_010723.1 identified by match to protein family HMM PF01098; stage V sporulation protein E 3343307 6317266 CLH_3096 Clostridium botulinum E3 str. Alaska E43 stage V sporulation protein E YP_001922473.1 3342117 R 508767 CDS YP_001922474.1 188588667 6318083 complement(3343359..3343802) 1 NC_010723.1 identified by match to protein family HMM PF00498; FHA-domain containing protein 3343802 6318083 CLH_3097 Clostridium botulinum E3 str. Alaska E43 FHA-domain containing protein YP_001922474.1 3343359 R 508767 CDS YP_001922475.1 188590443 6318229 complement(3344176..3346998) 1 NC_010723.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 3346998 uvrA 6318229 uvrA Clostridium botulinum E3 str. Alaska E43 excinuclease ABC subunit A YP_001922475.1 3344176 R 508767 CDS YP_001922476.1 188590418 6318432 complement(3347003..3348976) 1 NC_010723.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 3348976 uvrB 6318432 uvrB Clostridium botulinum E3 str. Alaska E43 excinuclease ABC subunit B YP_001922476.1 3347003 R 508767 CDS YP_001922477.1 188587687 6318544 complement(3349512..3350801) 1 NC_010723.1 hypothetical protein 3350801 6318544 CLH_3100 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922477.1 3349512 R 508767 CDS YP_001922478.1 188588524 6319202 complement(3350812..3352071) 1 NC_010723.1 identified by match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; carboxyl-terminal protease 3352071 6319202 CLH_3101 Clostridium botulinum E3 str. Alaska E43 carboxyl-terminal protease YP_001922478.1 3350812 R 508767 CDS YP_001922479.1 188589901 6320513 complement(3352447..3353337) 1 NC_010723.1 identified by match to protein family HMM PF02687; cell-division protein 3353337 6320513 CLH_3102 Clostridium botulinum E3 str. Alaska E43 cell-division protein YP_001922479.1 3352447 R 508767 CDS YP_001922480.1 188587549 6320351 complement(3353327..3354013) 1 NC_010723.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673; cell division ATP-binding protein FtsE 3354013 ftsE 6320351 ftsE Clostridium botulinum E3 str. Alaska E43 cell division ATP-binding protein FtsE YP_001922480.1 3353327 R 508767 CDS YP_001922481.1 188588123 6318711 complement(3354131..3354982) 1 NC_010723.1 identified by match to protein family HMM PF02588; transporter 3354982 6318711 CLH_3104 Clostridium botulinum E3 str. Alaska E43 transporter YP_001922481.1 3354131 R 508767 CDS YP_001922483.1 188590376 6317498 complement(3355387..3356331) 1 NC_010723.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase 3356331 6317498 CLH_3106 Clostridium botulinum E3 str. Alaska E43 transketolase YP_001922483.1 3355387 R 508767 CDS YP_001922484.1 188588027 6320487 complement(3356331..3357155) 1 NC_010723.1 identified by match to protein family HMM PF00456; transketolase 3357155 6320487 CLH_3107 Clostridium botulinum E3 str. Alaska E43 transketolase YP_001922484.1 3356331 R 508767 CDS YP_001922485.1 188588522 6317956 complement(3357430..3357783) 1 NC_010723.1 identified by match to protein family HMM PF02452; endoribonuclease endoA 3357783 6317956 CLH_3108 Clostridium botulinum E3 str. Alaska E43 endoribonuclease endoA YP_001922485.1 3357430 R 508767 CDS YP_001922486.1 188590731 6320543 complement(3357793..3358047) 1 NC_010723.1 hypothetical protein 3358047 6320543 CLH_3109 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922486.1 3357793 R 508767 CDS YP_001922487.1 188590207 6317866 complement(3358415..3359044) 1 NC_010723.1 putative membrane associated protein 3359044 6317866 CLH_3110 Clostridium botulinum E3 str. Alaska E43 putative membrane associated protein YP_001922487.1 3358415 R 508767 CDS YP_001922488.1 188587626 6317368 complement(3359110..3360609) 1 NC_010723.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; YjeF family protein 3360609 6317368 CLH_3111 Clostridium botulinum E3 str. Alaska E43 YjeF family protein YP_001922488.1 3359110 R 508767 CDS YP_001922489.1 188588811 6319652 complement(3360611..3360982) 1 NC_010723.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 3360982 acpS 6319652 acpS Clostridium botulinum E3 str. Alaska E43 4'-phosphopantetheinyl transferase YP_001922489.1 3360611 R 508767 CDS YP_001922490.1 188589516 6319303 complement(3361057..3361380) 1 NC_010723.1 hypothetical protein 3361380 6319303 CLH_3113 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922490.1 3361057 R 508767 CDS YP_001922491.1 188590638 6318066 complement(3362326..3362673) 1 NC_010723.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-strand binding protein family 3362673 6318066 CLH_3114 Clostridium botulinum E3 str. Alaska E43 single-strand binding protein family YP_001922491.1 3362326 R 508767 CDS YP_001922492.1 188588648 6317920 complement(3362745..3363593) 1 NC_010723.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765; YihY family protein 3363593 6317920 CLH_3115 Clostridium botulinum E3 str. Alaska E43 YihY family protein YP_001922492.1 3362745 R 508767 CDS YP_001922493.1 188587624 6317586 complement(3363946..3365262) 1 NC_010723.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03446; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 3365262 6317586 CLH_3116 Clostridium botulinum E3 str. Alaska E43 UDP-glucose 6-dehydrogenase YP_001922493.1 3363946 R 508767 CDS YP_001922494.1 188589995 6319650 complement(3365263..3365853) 1 NC_010723.1 identified by match to protein family HMM PF00132; hexapeptide transferase family protein 3365853 6319650 CLH_3117 Clostridium botulinum E3 str. Alaska E43 hexapeptide transferase family protein YP_001922494.1 3365263 R 508767 CDS YP_001922495.1 188589401 6320212 complement(3365867..3367048) 1 NC_010723.1 identified by match to protein family HMM PF01041; match to protein family HMM PF01212; erythromycin biosynthesis sensory transduction protein eryC1 3367048 6320212 CLH_3118 Clostridium botulinum E3 str. Alaska E43 erythromycin biosynthesis sensory transduction protein eryC1 YP_001922495.1 3365867 R 508767 CDS YP_001922496.1 188589306 6318638 complement(3367443..3368036) 1 NC_010723.1 identified by match to protein family HMM PF08876; hypothetical protein 3368036 6318638 CLH_3119 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922496.1 3367443 R 508767 CDS YP_001922497.1 188589000 6317511 3368656..3368901 1 NC_010723.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; transcriptional regulator, AbrB family 3368901 6317511 CLH_3120 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, AbrB family YP_001922497.1 3368656 D 508767 CDS YP_001922498.1 188588287 6319700 complement(3368967..3369812) 1 NC_010723.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein 3369812 6319700 CLH_3121 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922498.1 3368967 R 508767 CDS YP_001922499.1 188587917 6319800 complement(3369814..3370566) 1 NC_010723.1 identified by match to protein family HMM PF05175; SAM-dependent methyltransferase 3370566 6319800 CLH_3122 Clostridium botulinum E3 str. Alaska E43 SAM-dependent methyltransferase YP_001922499.1 3369814 R 508767 CDS YP_001922500.1 188589650 6318241 complement(3370810..3372084) 1 NC_010723.1 identified by match to protein family HMM PF00877; SagA protein 3372084 6318241 CLH_3123 Clostridium botulinum E3 str. Alaska E43 SagA protein YP_001922500.1 3370810 R 508767 CDS YP_001922501.1 188588251 6320495 3372526..3373170 1 NC_010723.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; haloacid dehalogenase 3373170 6320495 CLH_3124 Clostridium botulinum E3 str. Alaska E43 haloacid dehalogenase YP_001922501.1 3372526 D 508767 CDS YP_001922502.1 188589997 6319538 complement(3373389..3374132) 1 NC_010723.1 identified by match to protein family HMM PF00639; foldase protein PrsA 3374132 6319538 CLH_3125 Clostridium botulinum E3 str. Alaska E43 foldase protein PrsA YP_001922502.1 3373389 R 508767 CDS YP_001922503.1 188589647 6319735 3374263..3374940 1 NC_010723.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3374940 ung 6319735 ung Clostridium botulinum E3 str. Alaska E43 uracil-DNA glycosylase YP_001922503.1 3374263 D 508767 CDS YP_001922504.1 188588893 6320031 complement(3375166..3375363) 1 NC_010723.1 hypothetical protein 3375363 6320031 CLH_3127 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922504.1 3375166 R 508767 CDS YP_001922505.1 188588646 6318420 3375750..3376169 1 NC_010723.1 hypothetical protein 3376169 6318420 CLH_3128 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922505.1 3375750 D 508767 CDS YP_001922506.1 188588837 6320090 complement(3376859..3377350) 1 NC_010723.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; molybdopterin biosynthesis mog protein 3377350 6320090 CLH_3131 Clostridium botulinum E3 str. Alaska E43 molybdopterin biosynthesis mog protein YP_001922506.1 3376859 R 508767 CDS YP_001922507.1 188590397 6317241 complement(3377787..3378242) 1 NC_010723.1 identified by match to protein family HMM PF06445; AraC family transcriptional regulator 3378242 6317241 CLH_3132 Clostridium botulinum E3 str. Alaska E43 AraC family transcriptional regulator YP_001922507.1 3377787 R 508767 CDS YP_001922508.1 188587651 6318000 complement(3378310..3379206) 1 NC_010723.1 identified by match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR-family transcriptional regulator 3379206 6318000 CLH_3133 Clostridium botulinum E3 str. Alaska E43 DeoR-family transcriptional regulator YP_001922508.1 3378310 R 508767 CDS YP_001922509.1 188587670 6319958 complement(3379362..3379913) 1 NC_010723.1 identified by match to protein family HMM PF05685; hypothetical protein 3379913 6319958 CLH_3134 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922509.1 3379362 R 508767 CDS YP_001922510.1 188588449 6319807 complement(3380139..3380693) 1 NC_010723.1 identified by match to protein family HMM PF00583; acetyltransferase, GNAT family 3380693 6319807 CLH_3135 Clostridium botulinum E3 str. Alaska E43 acetyltransferase, GNAT family YP_001922510.1 3380139 R 508767 CDS YP_001922511.1 188589945 6318884 3380827..3381564 1 NC_010723.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 3381564 6318884 CLH_3136 Clostridium botulinum E3 str. Alaska E43 NAD-dependent deacetylase YP_001922511.1 3380827 D 508767 CDS YP_001922512.1 188590710 6319723 complement(3381747..3382664) 1 NC_010723.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate-protein ligase A 3382664 6319723 CLH_3137 Clostridium botulinum E3 str. Alaska E43 lipoate-protein ligase A YP_001922512.1 3381747 R 508767 CDS YP_001922513.1 188588124 6318738 complement(3382657..3384357) 1 NC_010723.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoyl dehydrogenase 3384357 lpdA 6318738 lpdA Clostridium botulinum E3 str. Alaska E43 dihydrolipoyl dehydrogenase YP_001922513.1 3382657 R 508767 CDS YP_001922514.1 188589123 6317843 complement(3384449..3384802) 1 NC_010723.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; alkylhydroperoxidase AhpD domain-containing protein 3384802 6317843 CLH_3139 Clostridium botulinum E3 str. Alaska E43 alkylhydroperoxidase AhpD domain-containing protein YP_001922514.1 3384449 R 508767 CDS YP_001922515.1 188589934 6318286 complement(3384906..3385334) 1 NC_010723.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 3385334 6318286 CLH_3140 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, MarR family YP_001922515.1 3384906 R 508767 CDS YP_001922516.1 188588781 6319492 complement(3385732..3385902) 1 NC_010723.1 nitrogen-fixing NifU domain-containing protein 3385902 6319492 CLH_3141 Clostridium botulinum E3 str. Alaska E43 nitrogen-fixing NifU domain-containing protein YP_001922516.1 3385732 R 508767 CDS YP_001922517.1 188590437 6318367 3386269..3386718 1 NC_010723.1 hypothetical protein 3386718 6318367 CLH_3142 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922517.1 3386269 D 508767 CDS YP_001922518.1 188587874 6318197 complement(3386998..3388008) 1 NC_010723.1 identified by match to protein family HMM PF02517; caax amino protease family protein 3388008 6318197 CLH_3143 Clostridium botulinum E3 str. Alaska E43 caax amino protease family protein YP_001922518.1 3386998 R 508767 CDS YP_001922519.1 188588517 6317733 complement(3388247..3388732) 1 NC_010723.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; CinA family protein 3388732 6317733 CLH_3144 Clostridium botulinum E3 str. Alaska E43 CinA family protein YP_001922519.1 3388247 R 508767 CDS YP_001922520.1 188589226 6318755 complement(3388756..3389364) 1 NC_010723.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 3389364 6318755 CLH_3145 Clostridium botulinum E3 str. Alaska E43 phosphoglycerate mutase family protein YP_001922520.1 3388756 R 508767 CDS YP_001922521.1 188589491 6320370 complement(3389606..3390559) 1 NC_010723.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744; glucokinase 3390559 6320370 CLH_3146 Clostridium botulinum E3 str. Alaska E43 glucokinase YP_001922521.1 3389606 R 508767 CDS YP_001922522.1 188590203 6320250 complement(3390678..3390914) 1 NC_010723.1 hypothetical protein 3390914 6320250 CLH_3147 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922522.1 3390678 R 508767 CDS YP_001922523.1 188590730 6317591 complement(3391078..3393159) 1 NC_010723.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3393159 fusA 6317591 fusA Clostridium botulinum E3 str. Alaska E43 elongation factor G YP_001922523.1 3391078 R 508767 CDS YP_001922524.1 188590030 6318826 3393466..3394962 1 NC_010723.1 hypothetical protein 3394962 6318826 CLH_3149 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922524.1 3393466 D 508767 CDS YP_001922525.1 188589981 6318873 3395187..3397004 1 NC_010723.1 identified by match to protein family HMM PF00884; sulfatase family protein 3397004 6318873 CLH_3150 Clostridium botulinum E3 str. Alaska E43 sulfatase family protein YP_001922525.1 3395187 D 508767 CDS YP_001922526.1 188589143 6319363 3397359..3399179 1 NC_010723.1 identified by match to protein family HMM PF00884; sulfatase family protein 3399179 6319363 CLH_3151 Clostridium botulinum E3 str. Alaska E43 sulfatase family protein YP_001922526.1 3397359 D 508767 CDS YP_001922527.1 188587591 6319168 complement(3399311..3400846) 1 NC_010723.1 identified by match to protein family HMM PF02667; match to protein family HMM PF03606; match to protein family HMM PF03806; aminobenzoyl-glutamate transport protein 3400846 6319168 CLH_3152 Clostridium botulinum E3 str. Alaska E43 aminobenzoyl-glutamate transport protein YP_001922527.1 3399311 R 508767 CDS YP_001922528.1 188590421 6318190 complement(3401085..3401543) 1 NC_010723.1 identified by match to protein family HMM PF04892; acetobutylicum phosphotransbutyrylase 3401543 6318190 CLH_3153 Clostridium botulinum E3 str. Alaska E43 acetobutylicum phosphotransbutyrylase YP_001922528.1 3401085 R 508767 CDS YP_001922529.1 188589726 6320616 complement(3401714..3402151) 1 NC_010723.1 hypothetical protein 3402151 6320616 CLH_3154 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922529.1 3401714 R 508767 CDS YP_001922530.1 188588005 6318995 3402483..3402881 1 NC_010723.1 putative lipoprotein 3402881 6318995 CLH_3155 Clostridium botulinum E3 str. Alaska E43 putative lipoprotein YP_001922530.1 3402483 D 508767 CDS YP_001922531.1 188589297 6320139 complement(3408523..3409629) 1 NC_010723.1 identified by match to protein family HMM TIGR02092; glucose-1-phosphate adenylyltransferase, GlgD subunit 3409629 glgD 6320139 glgD Clostridium botulinum E3 str. Alaska E43 glucose-1-phosphate adenylyltransferase, GlgD subunit YP_001922531.1 3408523 R 508767 CDS YP_001922532.1 188590636 6320523 complement(3409651..3410811) 1 NC_010723.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3410811 glgC 6320523 glgC Clostridium botulinum E3 str. Alaska E43 glucose-1-phosphate adenylyltransferase YP_001922532.1 3409651 R 508767 CDS YP_001922533.1 188588390 6318150 complement(3410909..3412723) 1 NC_010723.1 identified by match to protein family HMM PF00128; amylopullulanase 3412723 6318150 CLH_3164 Clostridium botulinum E3 str. Alaska E43 amylopullulanase YP_001922533.1 3410909 R 508767 CDS YP_001922534.1 188587657 6319718 complement(3412892..3415333) 1 NC_010723.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase 3415333 6319718 CLH_3165 Clostridium botulinum E3 str. Alaska E43 glycogen phosphorylase YP_001922534.1 3412892 R 508767 CDS YP_001922535.1 188589740 6319896 complement(3415364..3416800) 1 NC_010723.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3416800 glgA 6319896 glgA Clostridium botulinum E3 str. Alaska E43 glycogen synthase YP_001922535.1 3415364 R 508767 CDS YP_001922536.1 188589100 6319704 complement(3416943..3419189) 1 NC_010723.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 3419189 glgB 6319704 glgB Clostridium botulinum E3 str. Alaska E43 glycogen branching protein YP_001922536.1 3416943 R 508767 CDS YP_001922537.1 188588925 6318231 complement(3419835..3419954) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3419954 6318231 CLH_3168 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922537.1 3419835 R 508767 CDS YP_001922538.1 188590402 6318900 3425723..3426214 1 NC_010723.1 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system, glucose subfamily, IIA component 3426214 ptbA 6318900 ptbA Clostridium botulinum E3 str. Alaska E43 PTS system, glucose subfamily, IIA component YP_001922538.1 3425723 D 508767 CDS YP_001922539.1 188589470 6320037 complement(3426300..3427952) 1 NC_010723.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system, glucose-like IIB component 3427952 6320037 CLH_3174 Clostridium botulinum E3 str. Alaska E43 PTS system, glucose-like IIB component YP_001922539.1 3426300 R 508767 CDS YP_001922540.1 188589269 6319072 complement(3428196..3429050) 1 NC_010723.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LicT 3429050 6319072 CLH_3175 Clostridium botulinum E3 str. Alaska E43 transcription antiterminator LicT YP_001922540.1 3428196 R 508767 CDS YP_001922541.1 188588758 6318707 complement(3429271..3430218) 1 NC_010723.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 3430218 6318707 CLH_3176 Clostridium botulinum E3 str. Alaska E43 GNAT family acetyltransferase YP_001922541.1 3429271 R 508767 CDS YP_001922542.1 188588281 6318203 complement(3430340..3430606) 1 NC_010723.1 hypothetical protein 3430606 6318203 CLH_3177 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922542.1 3430340 R 508767 CDS YP_001922543.1 188589025 6319802 complement(3430659..3431003) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3431003 6319802 CLH_3178 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922543.1 3430659 R 508767 CDS YP_001922544.1 188589598 6317629 complement(3431562..3432920) 1 NC_010723.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 3432920 6317629 CLH_3179 Clostridium botulinum E3 str. Alaska E43 flagellin YP_001922544.1 3431562 R 508767 CDS YP_001922545.1 188589481 6319382 complement(3433381..3433542) 1 NC_010723.1 identified by match to protein family HMM PF02599; putative carbon storage regulator 3433542 6319382 CLH_3180 Clostridium botulinum E3 str. Alaska E43 putative carbon storage regulator YP_001922545.1 3433381 R 508767 CDS YP_001922546.1 188590371 6318584 complement(3434052..3435980) 1 NC_010723.1 identified by match to protein family HMM PF05976; hypothetical protein 3435980 6318584 CLH_3181 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922546.1 3434052 R 508767 CDS YP_001922547.1 188587595 6320504 complement(3436490..3437257) 1 NC_010723.1 identified by match to protein family HMM PF00899; thiF domain-containing protein 3437257 6320504 CLH_3182 Clostridium botulinum E3 str. Alaska E43 thiF domain-containing protein YP_001922547.1 3436490 R 508767 CDS YP_001922548.1 188588499 6319646 3437834..3438526 1 NC_010723.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 3438526 mtnN 6319646 mtnN Clostridium botulinum E3 str. Alaska E43 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001922548.1 3437834 D 508767 CDS YP_001922549.1 188589967 6320459 complement(3438588..3439940) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3439940 6320459 CLH_3184 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922549.1 3438588 R 508767 CDS YP_001922550.1 188590553 6320401 complement(3440118..3441269) 1 NC_010723.1 identified by match to protein family HMM PF07907; membrane protein, YbiE/YbiF family 3441269 6320401 CLH_3185 Clostridium botulinum E3 str. Alaska E43 membrane protein, YbiE/YbiF family YP_001922550.1 3440118 R 508767 CDS YP_001922551.1 188587990 6318120 complement(3441468..3445979) 1 NC_010723.1 identified by match to protein family HMM PF01336; OB-fold nucleic acid binding domain-containing protein 3445979 6318120 CLH_3186 Clostridium botulinum E3 str. Alaska E43 OB-fold nucleic acid binding domain-containing protein YP_001922551.1 3441468 R 508767 CDS YP_001922552.1 188590627 6318929 complement(3446341..3447471) 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3447471 6318929 CLH_3187 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922552.1 3446341 R 508767 CDS YP_001922553.1 188589664 6318507 complement(3447535..3448875) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3448875 6318507 CLH_3188 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922553.1 3447535 R 508767 CDS YP_001922554.1 188588734 6320610 complement(3448929..3449567) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3449567 6320610 CLH_3189 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922554.1 3448929 R 508767 CDS YP_001922555.1 188590575 6317317 complement(3449709..3450176) 1 NC_010723.1 identified by match to protein family HMM PF04892; acetobutylicum phosphotransbutyrylase 3450176 6317317 CLH_3190 Clostridium botulinum E3 str. Alaska E43 acetobutylicum phosphotransbutyrylase YP_001922555.1 3449709 R 508767 CDS YP_001922556.1 188588171 6318803 3450540..3451625 1 NC_010723.1 identified by match to protein family HMM PF01473; surface protein PspC 3451625 6318803 CLH_3191 Clostridium botulinum E3 str. Alaska E43 surface protein PspC YP_001922556.1 3450540 D 508767 CDS YP_001922557.1 188589109 6319455 complement(3451730..3453421) 1 NC_010723.1 identified by match to protein family HMM PF08011; hypothetical protein 3453421 6319455 CLH_3192 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922557.1 3451730 R 508767 CDS YP_001922558.1 188590153 6320489 complement(3453575..3454555) 1 NC_010723.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01714; hypothetical protein 3454555 6320489 CLH_3193 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922558.1 3453575 R 508767 CDS YP_001922559.1 188587840 6317763 complement(3454865..3455743) 1 NC_010723.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 3455743 galU 6317763 galU Clostridium botulinum E3 str. Alaska E43 UTP-glucose-1-phosphate uridylyltransferase YP_001922559.1 3454865 R 508767 CDS YP_001922560.1 188588705 6318691 complement(3455897..3456949) 1 NC_010723.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 3456949 rfbB 6318691 rfbB Clostridium botulinum E3 str. Alaska E43 dTDP-glucose 4,6-dehydratase YP_001922560.1 3455897 R 508767 CDS YP_001922561.1 188589422 6318610 complement(3457032..3457925) 1 NC_010723.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214; dTDP-4-dehydrorhamnose reductase 3457925 rfbD 6318610 rfbD Clostridium botulinum E3 str. Alaska E43 dTDP-4-dehydrorhamnose reductase YP_001922561.1 3457032 R 508767 CDS YP_001922562.1 188588633 6317749 complement(3458012..3458590) 1 NC_010723.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221; dTDP-4-dehydrorhamnose 3,5-epimerase 3458590 rfbC 6317749 rfbC Clostridium botulinum E3 str. Alaska E43 dTDP-4-dehydrorhamnose 3,5-epimerase YP_001922562.1 3458012 R 508767 CDS YP_001922563.1 188589164 6317304 complement(3458613..3459512) 1 NC_010723.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 3459512 rfbA 6317304 rfbA Clostridium botulinum E3 str. Alaska E43 glucose-1-phosphate thymidylyltransferase YP_001922563.1 3458613 R 508767 CDS YP_001922564.1 188590072 6320056 complement(3459920..3460750) 1 NC_010723.1 identified by match to protein family HMM PF00106; 3-oxoacyl-ACP reductase 3460750 6320056 CLH_3199 Clostridium botulinum E3 str. Alaska E43 3-oxoacyl-ACP reductase YP_001922564.1 3459920 R 508767 CDS YP_001922565.1 188588147 6317797 complement(3460769..3461773) 1 NC_010723.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 3461773 6317797 CLH_3200 Clostridium botulinum E3 str. Alaska E43 glycosyl transferase family protein YP_001922565.1 3460769 R 508767 CDS YP_001922566.1 188589081 6318689 complement(3461900..3462994) 1 NC_010723.1 hypothetical protein 3462994 6318689 CLH_3201 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922566.1 3461900 R 508767 CDS YP_001922567.1 188589674 6318778 complement(3463490..3464575) 1 NC_010723.1 hypothetical protein 3464575 6318778 CLH_3202 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922567.1 3463490 R 508767 CDS YP_001922568.1 188590536 6318311 complement(3465055..3466464) 1 NC_010723.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; putative polysaccharide transporter 3466464 6318311 CLH_3203 Clostridium botulinum E3 str. Alaska E43 putative polysaccharide transporter YP_001922568.1 3465055 R 508767 CDS YP_001922569.1 188590041 6318101 complement(3466451..3467149) 1 NC_010723.1 identified by match to protein family HMM PF04488; hypothetical protein 3467149 6318101 CLH_3204 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922569.1 3466451 R 508767 CDS YP_001922570.1 188589923 6320492 complement(3467163..3468137) 1 NC_010723.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 3468137 6320492 CLH_3205 Clostridium botulinum E3 str. Alaska E43 glycosyl transferase family protein YP_001922570.1 3467163 R 508767 CDS YP_001922571.1 188588586 6318422 complement(3468138..3468968) 1 NC_010723.1 identified by match to protein family HMM PF00535; hypothetical protein 3468968 6318422 CLH_3206 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922571.1 3468138 R 508767 CDS YP_001922572.1 188590330 6318672 complement(3469014..3469733) 1 NC_010723.1 identified by match to protein family HMM PF00132; hypothetical protein 3469733 6318672 CLH_3207 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922572.1 3469014 R 508767 CDS YP_001922573.1 188588080 6318328 complement(3469862..3470971) 1 NC_010723.1 identified by match to protein family HMM PF00534; hypothetical protein 3470971 6318328 CLH_3208 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922573.1 3469862 R 508767 CDS YP_001922574.1 188588788 6319273 complement(3470993..3471712) 1 NC_010723.1 identified by match to protein family HMM PF00483; mannose-1-phosphate guanylyltransferase 3471712 6319273 CLH_3209 Clostridium botulinum E3 str. Alaska E43 mannose-1-phosphate guanylyltransferase YP_001922574.1 3470993 R 508767 CDS YP_001922575.1 188589948 6317976 complement(3471726..3472397) 1 NC_010723.1 identified by match to protein family HMM PF02397; galactosyl transferase CpsE 3472397 6317976 CLH_3210 Clostridium botulinum E3 str. Alaska E43 galactosyl transferase CpsE YP_001922575.1 3471726 R 508767 CDS YP_001922576.1 188590155 6319752 complement(3472799..3473566) 1 NC_010723.1 identified by match to protein family HMM PF02811; putative tyrosine-protein phosphatase CapC 3473566 6319752 CLH_3211 Clostridium botulinum E3 str. Alaska E43 putative tyrosine-protein phosphatase CapC YP_001922576.1 3472799 R 508767 CDS YP_001922577.1 188590478 6317986 complement(3473746..3474489) 1 NC_010723.1 identified by match to protein family HMM TIGR01007; tyrosine-protein kinase etk 3474489 6317986 CLH_3212 Clostridium botulinum E3 str. Alaska E43 tyrosine-protein kinase etk YP_001922577.1 3473746 R 508767 CDS YP_001922578.1 188589542 6318966 complement(3474502..3475188) 1 NC_010723.1 identified by match to protein family HMM PF02706; capsular polysaccharide biosynthsis protein 3475188 6318966 CLH_3213 Clostridium botulinum E3 str. Alaska E43 capsular polysaccharide biosynthsis protein YP_001922578.1 3474502 R 508767 CDS YP_001922579.1 188588831 6320161 complement(3475708..3476295) 1 NC_010723.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221; dTDP-4-dehydrorhamnose 3,5-epimerase 3476295 rfbC 6320161 rfbC Clostridium botulinum E3 str. Alaska E43 dTDP-4-dehydrorhamnose 3,5-epimerase YP_001922579.1 3475708 R 508767 CDS YP_001922580.1 188588109 6319329 complement(3476405..3477724) 1 NC_010723.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS/transporter domain-containing protein 3477724 6319329 CLH_3215 Clostridium botulinum E3 str. Alaska E43 CBS/transporter domain-containing protein YP_001922580.1 3476405 R 508767 CDS YP_001922581.1 188590204 6319316 complement(3478080..3479336) 1 NC_010723.1 identified by match to protein family HMM PF06245; hypothetical protein 3479336 6319316 CLH_3216 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922581.1 3478080 R 508767 CDS YP_001922582.1 188587665 6317488 complement(3479719..3480627) 1 NC_010723.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-3-phosphoglycerate dehydrogenase 3480627 6317488 CLH_3217 Clostridium botulinum E3 str. Alaska E43 D-3-phosphoglycerate dehydrogenase YP_001922582.1 3479719 R 508767 CDS YP_001922583.1 188588385 6320131 complement(3480925..3481998) 1 NC_010723.1 identified by match to protein family HMM PF00266; aspartate aminotransferase 3481998 6320131 CLH_3218 Clostridium botulinum E3 str. Alaska E43 aspartate aminotransferase YP_001922583.1 3480925 R 508767 CDS YP_001922584.1 188589485 6319969 complement(3482696..3482881) 1 NC_010723.1 hypothetical protein 3482881 6319969 CLH_3219 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922584.1 3482696 R 508767 CDS YP_001922585.1 188587900 6320572 complement(3482971..3484185) 1 NC_010723.1 ABC transporter permease 3484185 6320572 CLH_3220 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001922585.1 3482971 R 508767 CDS YP_001922586.1 188588606 6317311 complement(3484186..3485100) 1 NC_010723.1 identified by match to protein family HMM PF00005; bacitracin transport ATP-binding protein BcrA 3485100 6317311 CLH_3221 Clostridium botulinum E3 str. Alaska E43 bacitracin transport ATP-binding protein BcrA YP_001922586.1 3484186 R 508767 CDS YP_001922587.1 188589717 6317345 complement(3485449..3485697) 1 NC_010723.1 identified by match to protein family HMM PF07441; match to protein family HMM TIGR02862; sigma-K factor-processing regulatory protein BofA 3485697 6317345 CLH_3222 Clostridium botulinum E3 str. Alaska E43 sigma-K factor-processing regulatory protein BofA YP_001922587.1 3485449 R 508767 CDS YP_001922588.1 188590452 6317894 complement(3485715..3485990) 1 NC_010723.1 hypothetical protein 3485990 6317894 CLH_3223 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922588.1 3485715 R 508767 CDS YP_001922589.1 188588858 6317363 complement(3486398..3486994) 1 NC_010723.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 3486994 recR 6317363 recR Clostridium botulinum E3 str. Alaska E43 recombination protein RecR YP_001922589.1 3486398 R 508767 CDS YP_001922590.1 188589889 6317420 complement(3487245..3487586) 1 NC_010723.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 3487586 6317420 CLH_3225 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922590.1 3487245 R 508767 CDS YP_001922591.1 188589354 6318750 complement(3487665..3489305) 1 NC_010723.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 3489305 dnaX 6318750 dnaX Clostridium botulinum E3 str. Alaska E43 DNA polymerase III subunits gamma and tau YP_001922591.1 3487665 R 508767 CDS YP_001922592.1 188590339 6318294 3489575..3490366 1 NC_010723.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3490366 thyA 6318294 thyA Clostridium botulinum E3 str. Alaska E43 thymidylate synthase YP_001922592.1 3489575 D 508767 CDS YP_001922593.1 188587792 6317990 3490478..3490972 1 NC_010723.1 identified by match to protein family HMM PF00186; dihydrofolate reductase 3490972 folA 6317990 folA Clostridium botulinum E3 str. Alaska E43 dihydrofolate reductase YP_001922593.1 3490478 D 508767 CDS YP_001922594.1 188588421 6317556 complement(3491970..3492152) 1 NC_010723.1 hypothetical protein 3492152 6317556 CLH_3229 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922594.1 3491970 R 508767 CDS YP_001922595.1 188589573 6320406 complement(3492679..3493221) 1 NC_010723.1 identified by match to protein family HMM PF01569; PAP2 family protein 3493221 6320406 CLH_3231 Clostridium botulinum E3 str. Alaska E43 PAP2 family protein YP_001922595.1 3492679 R 508767 CDS YP_001922596.1 188588285 6320281 complement(3493300..3493773) 1 NC_010723.1 identified by match to protein family HMM PF00383; tRNA-specific adenosine deaminase 3493773 6320281 CLH_3232 Clostridium botulinum E3 str. Alaska E43 tRNA-specific adenosine deaminase YP_001922596.1 3493300 R 508767 CDS YP_001922597.1 188589005 6319811 complement(3494101..3495354) 1 NC_010723.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; putative membrane CBS domain-containing protein 3495354 6319811 CLH_3233 Clostridium botulinum E3 str. Alaska E43 putative membrane CBS domain-containing protein YP_001922597.1 3494101 R 508767 CDS YP_001922598.1 188590447 6318228 complement(3495713..3496651) 1 NC_010723.1 identified by match to protein family HMM PF00294; fructokinase 3496651 6318228 CLH_3234 Clostridium botulinum E3 str. Alaska E43 fructokinase YP_001922598.1 3495713 R 508767 CDS YP_001922599.1 188589701 6317810 complement(3496644..3498104) 1 NC_010723.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 3498104 6317810 CLH_3235 Clostridium botulinum E3 str. Alaska E43 sucrose-6-phosphate hydrolase YP_001922599.1 3496644 R 508767 CDS YP_001922600.1 188589468 6320570 complement(3498123..3499115) 1 NC_010723.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sucrose repressor 3499115 6320570 CLH_3236 Clostridium botulinum E3 str. Alaska E43 sucrose repressor YP_001922600.1 3498123 R 508767 CDS YP_001922601.1 188588695 6319070 complement(3499291..3500646) 1 NC_010723.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR01996; PTS system sucrose-specific transporter subunit IIBC 3500646 6319070 CLH_3237 Clostridium botulinum E3 str. Alaska E43 PTS system sucrose-specific transporter subunit IIBC YP_001922601.1 3499291 R 508767 CDS YP_001922602.1 188589007 6320511 complement(3501149..3501310) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3501310 6320511 CLH_3238 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922602.1 3501149 R 508767 CDS YP_001922603.1 188588260 6319901 complement(3501467..3501871) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3501871 6319901 CLH_3239 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922603.1 3501467 R 508767 CDS YP_001922604.1 188590026 6319861 complement(3502082..3502549) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3502549 6319861 CLH_3240 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922604.1 3502082 R 508767 CDS YP_001922605.1 188589348 6319188 complement(3502987..3503754) 1 NC_010723.1 identified by match to protein family HMM PF00290; match to protein family HMM TIGR00262; tryptophan synthase subunit alpha 3503754 trpA 6319188 trpA Clostridium botulinum E3 str. Alaska E43 tryptophan synthase subunit alpha YP_001922605.1 3502987 R 508767 CDS YP_001922606.1 188589572 6318534 complement(3503708..3504856) 1 NC_010723.1 identified by match to protein family HMM PF00465; NADPH-dependent butanol dehydrogenase 3504856 6318534 CLH_3242 Clostridium botulinum E3 str. Alaska E43 NADPH-dependent butanol dehydrogenase YP_001922606.1 3503708 R 508767 CDS YP_001922607.1 188590120 6320280 complement(3504967..3505761) 1 NC_010723.1 identified by match to protein family HMM PF03437; match to protein family HMM TIGR00259; hypothetical protein 3505761 6320280 CLH_3243 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922607.1 3504967 R 508767 CDS YP_001922608.1 188588600 6317644 3505712..3505825 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3505825 6317644 CLH_3245 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922608.1 3505712 D 508767 CDS YP_001922609.1 188588120 6318843 complement(3505784..3506539) 1 NC_010723.1 identified by match to protein family HMM PF01048; uridine phosphorylase 3506539 6318843 CLH_3244 Clostridium botulinum E3 str. Alaska E43 uridine phosphorylase YP_001922609.1 3505784 R 508767 CDS YP_001922610.1 188589086 6318875 complement(3506539..3507489) 1 NC_010723.1 identified by match to protein family HMM PF00294; kinase, PfkB family 3507489 6318875 CLH_3246 Clostridium botulinum E3 str. Alaska E43 kinase, PfkB family YP_001922610.1 3506539 R 508767 CDS YP_001922611.1 188590172 6320417 complement(3507505..3508071) 1 NC_010723.1 identified by match to protein family HMM PF00857; isochorismatase family protein 3508071 6320417 CLH_3247 Clostridium botulinum E3 str. Alaska E43 isochorismatase family protein YP_001922611.1 3507505 R 508767 CDS YP_001922612.1 188589589 6318340 complement(3508091..3509005) 1 NC_010723.1 identified by match to protein family HMM PF02653; inner-membrane translocator 3509005 6318340 CLH_3248 Clostridium botulinum E3 str. Alaska E43 inner-membrane translocator YP_001922612.1 3508091 R 508767 CDS YP_001922613.1 188588900 6319208 complement(3509005..3510066) 1 NC_010723.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 3510066 6319208 CLH_3249 Clostridium botulinum E3 str. Alaska E43 sugar ABC transporter permease YP_001922613.1 3509005 R 508767 CDS YP_001922614.1 188588572 6318549 complement(3510063..3511610) 1 NC_010723.1 identified by match to protein family HMM PF00005; ribose import ATP-binding protein RbsA 3511610 6318549 CLH_3250 Clostridium botulinum E3 str. Alaska E43 ribose import ATP-binding protein RbsA YP_001922614.1 3510063 R 508767 CDS YP_001922615.1 188587939 6319435 complement(3511632..3512816) 1 NC_010723.1 identified by match to protein family HMM PF02608; putative basic membrane lipoprotein 3512816 6319435 CLH_3251 Clostridium botulinum E3 str. Alaska E43 putative basic membrane lipoprotein YP_001922615.1 3511632 R 508767 CDS YP_001922616.1 188590102 6317569 complement(3512882..3513610) 1 NC_010723.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; transcriptional regulator 3513610 6317569 CLH_3252 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001922616.1 3512882 R 508767 CDS YP_001922617.1 188589294 6317357 complement(3514078..3514803) 1 NC_010723.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; transcriptional regulator 3514803 6317357 CLH_3253 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator YP_001922617.1 3514078 R 508767 CDS YP_001922618.1 188588937 6317589 complement(3515493..3516149) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3516149 6317589 CLH_3255 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922618.1 3515493 R 508767 CDS YP_001922619.1 188588044 6318904 complement(3516173..3518545) 1 NC_010723.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; P-type ATPase - metal cation transport 3518545 6318904 CLH_3256 Clostridium botulinum E3 str. Alaska E43 P-type ATPase - metal cation transport YP_001922619.1 3516173 R 508767 CDS YP_001922620.1 188590683 6318511 3518844..3519563 1 NC_010723.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-acyl-sn-glycerol-3-phosphate acyltransferase 3519563 6318511 CLH_3257 Clostridium botulinum E3 str. Alaska E43 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001922620.1 3518844 D 508767 CDS YP_001922621.1 188589982 6317942 3519719..3521299 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; ATP-dependent RNA helicase DbpA 3521299 6317942 CLH_3258 Clostridium botulinum E3 str. Alaska E43 ATP-dependent RNA helicase DbpA YP_001922621.1 3519719 D 508767 CDS YP_001922622.1 188590254 6319364 complement(3521347..3521868) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3521868 6319364 CLH_3259 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922622.1 3521347 R 508767 CDS YP_001922623.1 188587783 6318068 complement(3521968..3522588) 1 NC_010723.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; HD superfamily hydrolase 3522588 6318068 CLH_3260 Clostridium botulinum E3 str. Alaska E43 HD superfamily hydrolase YP_001922623.1 3521968 R 508767 CDS YP_001922624.1 188588719 6318662 complement(3523032..3523979) 1 NC_010723.1 identified by match to protein family HMM PF01636; putative phosphotransferase enzyme family 3523979 6318662 CLH_3261 Clostridium botulinum E3 str. Alaska E43 putative phosphotransferase enzyme family YP_001922624.1 3523032 R 508767 CDS YP_001922625.1 188589763 6317808 complement(3524172..3524330) 1 NC_010723.1 identified by match to protein family HMM PF07561; hypothetical protein 3524330 6317808 CLH_3262 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922625.1 3524172 R 508767 CDS YP_001922626.1 188588541 6320120 3524598..3525686 1 NC_010723.1 hypothetical protein 3525686 6320120 CLH_3263 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922626.1 3524598 D 508767 CDS YP_001922627.1 188589413 6319141 complement(3526109..3527053) 1 NC_010723.1 identified by match to protein family HMM PF01497; ferric siderophore ABC transporter,substrate-binding protein 3527053 6319141 CLH_3264 Clostridium botulinum E3 str. Alaska E43 ferric siderophore ABC transporter,substrate-binding protein YP_001922627.1 3526109 R 508767 CDS YP_001922628.1 188589711 6317566 complement(3527325..3528080) 1 NC_010723.1 identified by match to protein family HMM PF00005; ferrichrome transport ATP-binding protein FhuC 3528080 6317566 CLH_3265 Clostridium botulinum E3 str. Alaska E43 ferrichrome transport ATP-binding protein FhuC YP_001922628.1 3527325 R 508767 CDS YP_001922629.1 188590493 6318284 complement(3528077..3529027) 1 NC_010723.1 identified by match to protein family HMM PF01032; iron chelate uptake ABC transporter permease 3529027 6318284 CLH_3266 Clostridium botulinum E3 str. Alaska E43 iron chelate uptake ABC transporter permease YP_001922629.1 3528077 R 508767 CDS YP_001922630.1 188588775 6318850 complement(3529017..3529970) 1 NC_010723.1 identified by match to protein family HMM PF01032; iron chelate uptake ABC transporter permease 3529970 6318850 CLH_3267 Clostridium botulinum E3 str. Alaska E43 iron chelate uptake ABC transporter permease YP_001922630.1 3529017 R 508767 CDS YP_001922631.1 188589834 6317380 3530163..3530924 1 NC_010723.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 3530924 6317380 CLH_3268 Clostridium botulinum E3 str. Alaska E43 AraC family transcriptional regulator YP_001922631.1 3530163 D 508767 CDS YP_001922632.1 188589752 6320020 complement(3531449..3533110) 1 NC_010723.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM PF01740; match to protein family HMM TIGR00815; sulfate permease family protein 3533110 6320020 CLH_3269 Clostridium botulinum E3 str. Alaska E43 sulfate permease family protein YP_001922632.1 3531449 R 508767 CDS YP_001922633.1 188590500 6319894 complement(3533707..3534579) 1 NC_010723.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3534579 dapA 6319894 dapA Clostridium botulinum E3 str. Alaska E43 dihydrodipicolinate synthase YP_001922633.1 3533707 R 508767 CDS YP_001922634.1 188587851 6319040 complement(3534688..3534804) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3534804 6319040 CLH_3271 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922634.1 3534688 R 508767 CDS YP_001922635.1 188588652 6319087 3535472..3536275 1 NC_010723.1 hypothetical protein 3536275 6319087 CLH_3272 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922635.1 3535472 D 508767 CDS YP_001922636.1 188589382 6317372 complement(3536627..3537376) 1 NC_010723.1 identified by match to protein family HMM PF01925; transporter 3537376 6317372 CLH_3273 Clostridium botulinum E3 str. Alaska E43 transporter YP_001922636.1 3536627 R 508767 CDS YP_001922637.1 188590104 6318217 complement(3537460..3538140) 1 NC_010723.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906; integral membrane protein 3538140 6318217 CLH_3274 Clostridium botulinum E3 str. Alaska E43 integral membrane protein YP_001922637.1 3537460 R 508767 CDS YP_003264530.1 261876181 8538026 complement(3550522..3550650) 1 NC_010723.1 Gfo/Idh/MocA family; oxidoreductase 3550650 8538026 CLH_3284 Clostridium botulinum E3 str. Alaska E43 oxidoreductase YP_003264530.1 3550522 R 508767 CDS YP_001922638.1 188589741 6320137 complement(3567889..3568788) 1 NC_010723.1 identified by match to protein family HMM PF01734; phospholipase, patatin family 3568788 6320137 CLH_3297 Clostridium botulinum E3 str. Alaska E43 phospholipase, patatin family YP_001922638.1 3567889 R 508767 CDS YP_001922639.1 188588546 6319705 complement(3568822..3569640) 1 NC_010723.1 identified by match to protein family HMM PF03618; hypothetical protein 3569640 6319705 CLH_3298 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922639.1 3568822 R 508767 CDS YP_001922640.1 188589239 6318323 3570103..3570861 1 NC_010723.1 hypothetical protein 3570861 6318323 CLH_3299 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922640.1 3570103 D 508767 CDS YP_001922641.1 188590462 6318986 3571083..3572276 1 NC_010723.1 identified by match to protein family HMM PF01926; match to protein family HMM PF08477; match to protein family HMM TIGR00231; GTP-binding protein 3572276 6318986 CLH_3300 Clostridium botulinum E3 str. Alaska E43 GTP-binding protein YP_001922641.1 3571083 D 508767 CDS YP_001922642.1 188587883 6320091 complement(3573165..3573899) 1 NC_010723.1 identified by match to protein family HMM PF00691; chemotaxis MotB protein 3573899 motB 6320091 motB Clostridium botulinum E3 str. Alaska E43 chemotaxis MotB protein YP_001922642.1 3573165 R 508767 CDS YP_001922643.1 188588133 6319815 complement(3573904..3574680) 1 NC_010723.1 identified by match to protein family HMM PF01618; chemotaxis protein MotA 3574680 6319815 CLH_3304 Clostridium botulinum E3 str. Alaska E43 chemotaxis protein MotA YP_001922643.1 3573904 R 508767 CDS YP_001922644.1 188588768 6318521 complement(3574996..3575943) 1 NC_010723.1 identified by match to protein family HMM PF00056; match to protein family HMM PF02866; match to protein family HMM TIGR01771; L-lactate dehydrogenase 3575943 6318521 CLH_3305 Clostridium botulinum E3 str. Alaska E43 L-lactate dehydrogenase YP_001922644.1 3574996 R 508767 CDS YP_001922645.1 188589818 6317852 3582004..3584043 1 NC_010723.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; putative methyl-accepting chemotaxis protein 3584043 6317852 CLH_3311 Clostridium botulinum E3 str. Alaska E43 putative methyl-accepting chemotaxis protein YP_001922645.1 3582004 D 508767 CDS YP_001922646.1 188589772 6320102 complement(3584248..3585258) 1 NC_010723.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; two-component sensor histidine kinase 3585258 6320102 CLH_3312 Clostridium botulinum E3 str. Alaska E43 two-component sensor histidine kinase YP_001922646.1 3584248 R 508767 CDS YP_001922647.1 188588827 6320253 complement(3585255..3585926) 1 NC_010723.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 3585926 6320253 CLH_3313 Clostridium botulinum E3 str. Alaska E43 DNA-binding response regulator YP_001922647.1 3585255 R 508767 CDS YP_001922648.1 188588134 6318184 complement(3586051..3588066) 1 NC_010723.1 identified by match to protein family HMM PF02687; ABC transporter permease 3588066 6318184 CLH_3314 Clostridium botulinum E3 str. Alaska E43 ABC transporter permease YP_001922648.1 3586051 R 508767 CDS YP_001922649.1 188589471 6318522 complement(3588056..3588823) 1 NC_010723.1 identified by match to protein family HMM PF00005; bacitracin export ATP-binding protein BceA 3588823 6318522 CLH_3315 Clostridium botulinum E3 str. Alaska E43 bacitracin export ATP-binding protein BceA YP_001922649.1 3588056 R 508767 CDS YP_001922650.1 188587750 6317824 complement(3589194..3589625) 1 NC_010723.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 3589625 6317824 CLH_3316 Clostridium botulinum E3 str. Alaska E43 transcriptional regulator, MarR family YP_001922650.1 3589194 R 508767 CDS YP_001922651.1 188590059 6318656 complement(3589933..3590244) 1 NC_010723.1 identified by match to protein family HMM PF00085; thioredoxin 3590244 6318656 CLH_3317 Clostridium botulinum E3 str. Alaska E43 thioredoxin YP_001922651.1 3589933 R 508767 CDS YP_001922652.1 188589848 6317804 complement(3590448..3591692) 1 NC_010723.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; HD domain-containing protein 3591692 6317804 CLH_3318 Clostridium botulinum E3 str. Alaska E43 HD domain-containing protein YP_001922652.1 3590448 R 508767 CDS YP_001922653.1 188588888 6319459 complement(3592169..3592804) 1 NC_010723.1 identified by glimmer; putative; hypothetical protein 3592804 6319459 CLH_3319 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922653.1 3592169 R 508767 CDS YP_001922654.1 188589917 6320324 complement(3593016..3593408) 1 NC_010723.1 hypothetical protein 3593408 6320324 CLH_3320 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922654.1 3593016 R 508767 CDS YP_001922655.1 188589704 6317518 complement(3593410..3593841) 1 NC_010723.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01978; MarR family regulatory protein 3593841 6317518 CLH_3321 Clostridium botulinum E3 str. Alaska E43 MarR family regulatory protein YP_001922655.1 3593410 R 508767 CDS YP_001922656.1 188588794 6317331 complement(3593860..3594318) 1 NC_010723.1 hypothetical protein 3594318 6317331 CLH_3322 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922656.1 3593860 R 508767 CDS YP_001922657.1 188590321 6317687 complement(3594700..3595626) 1 NC_010723.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase 3595626 6317687 CLH_3323 Clostridium botulinum E3 str. Alaska E43 transketolase YP_001922657.1 3594700 R 508767 CDS YP_001922658.1 188590622 6320500 complement(3595643..3596455) 1 NC_010723.1 identified by match to protein family HMM PF00456; transketolase 3596455 6320500 CLH_3324 Clostridium botulinum E3 str. Alaska E43 transketolase YP_001922658.1 3595643 R 508767 CDS YP_001922659.1 188590109 6318492 complement(3596535..3597884) 1 NC_010723.1 identified by match to protein family HMM PF04215; PTS system ascorbate-specific transporter subunit IIC 3597884 6318492 CLH_3325 Clostridium botulinum E3 str. Alaska E43 PTS system ascorbate-specific transporter subunit IIC YP_001922659.1 3596535 R 508767 CDS YP_001922660.1 188587931 6317470 complement(3597955..3598230) 1 NC_010723.1 identified by match to protein family HMM PF02302; PTS system mannitol-specific transporter subunit IIB 3598230 6317470 CLH_3326 Clostridium botulinum E3 str. Alaska E43 PTS system mannitol-specific transporter subunit IIB YP_001922660.1 3597955 R 508767 CDS YP_001922661.1 188588700 6319024 complement(3598233..3598634) 1 NC_010723.1 identified by match to protein family HMM PF00359; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3598634 6319024 CLH_3327 Clostridium botulinum E3 str. Alaska E43 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_001922661.1 3598233 R 508767 CDS YP_001922662.1 188589788 6318619 complement(3598649..3600535) 1 NC_010723.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; match to protein family HMM PF02302; match to protein family HMM PF08279; putative phosphotransferase system mannitol/fructose-specific IIA domain 3600535 6318619 CLH_3328 Clostridium botulinum E3 str. Alaska E43 putative phosphotransferase system mannitol/fructose-specific IIA domain YP_001922662.1 3598649 R 508767 CDS YP_001922663.1 188590490 6318357 complement(3601138..3601614) 1 NC_010723.1 identified by match to protein family HMM PF00255; glutathione peroxidase 3601614 6318357 CLH_3329 Clostridium botulinum E3 str. Alaska E43 glutathione peroxidase YP_001922663.1 3601138 R 508767 CDS YP_001922664.1 188588930 6318828 complement(3601827..3603491) 1 NC_010723.1 identified by match to protein family HMM PF00128; oligo-1,6-glucosidase 3603491 6318828 CLH_3330 Clostridium botulinum E3 str. Alaska E43 oligo-1,6-glucosidase YP_001922664.1 3601827 R 508767 CDS YP_001922665.1 188589680 6318866 complement(3603646..3604563) 1 NC_010723.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 3604563 6318866 CLH_3331 Clostridium botulinum E3 str. Alaska E43 AraC family transcriptional regulator YP_001922665.1 3603646 R 508767 CDS YP_001922666.1 188590180 6318058 complement(3605035..3606033) 1 NC_010723.1 identified by match to protein family HMM PF01384; phosphate permease 3606033 6318058 CLH_3332 Clostridium botulinum E3 str. Alaska E43 phosphate permease YP_001922666.1 3605035 R 508767 CDS YP_001922667.1 188588244 6320255 complement(3606026..3606658) 1 NC_010723.1 identified by match to protein family HMM PF01865; hypothetical protein 3606658 6320255 CLH_3333 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922667.1 3606026 R 508767 CDS YP_001922668.1 188588752 6319542 3606956..3608623 1 NC_010723.1 hypothetical protein 3608623 6319542 CLH_3334 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922668.1 3606956 D 508767 CDS YP_001922669.1 188589277 6317467 3609125..3610225 1 NC_010723.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 3610225 6317467 CLH_3335 Clostridium botulinum E3 str. Alaska E43 glycerophosphoryl diester phosphodiesterase YP_001922669.1 3609125 D 508767 CDS YP_001922670.1 188588559 6317448 complement(3610389..3610901) 1 NC_010723.1 flavodoxin family protein 3610901 6317448 CLH_3336 Clostridium botulinum E3 str. Alaska E43 flavodoxin family protein YP_001922670.1 3610389 R 508767 CDS YP_001922671.1 188589329 6319563 complement(3610958..3612058) 1 NC_010723.1 identified by match to protein family HMM PF00724; putative oxidoreductase 3612058 6319563 CLH_3337 Clostridium botulinum E3 str. Alaska E43 putative oxidoreductase YP_001922671.1 3610958 R 508767 CDS YP_001922672.1 188589616 6318757 complement(3612074..3612511) 1 NC_010723.1 identified by match to protein family HMM PF01047; MarR-family transcriptional regulator 3612511 6318757 CLH_3338 Clostridium botulinum E3 str. Alaska E43 MarR-family transcriptional regulator YP_001922672.1 3612074 R 508767 CDS YP_001922673.1 188587881 6319138 complement(3612723..3614021) 1 NC_010723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; putative ATP-dependent RNA helicase RhlE 3614021 6319138 CLH_3339 Clostridium botulinum E3 str. Alaska E43 putative ATP-dependent RNA helicase RhlE YP_001922673.1 3612723 R 508767 CDS YP_001922674.1 188587934 6317388 complement(3614352..3614504) 1 NC_010723.1 hypothetical protein 3614504 6317388 CLH_3340 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922674.1 3614352 R 508767 CDS YP_001922675.1 188588683 6320595 complement(3614776..3615282) 1 NC_010723.1 membrane protein 3615282 6320595 CLH_3341 Clostridium botulinum E3 str. Alaska E43 membrane protein YP_001922675.1 3614776 R 508767 CDS YP_001922676.1 188589201 6317770 complement(3615445..3615924) 1 NC_010723.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 3615924 6317770 CLH_3342 Clostridium botulinum E3 str. Alaska E43 rRNA large subunit methyltransferase YP_001922676.1 3615445 R 508767 CDS YP_001922677.1 188590302 6317408 complement(3616214..3616873) 1 NC_010723.1 identified by match to protein family HMM PF06555; hypothetical protein 3616873 6317408 CLH_3343 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922677.1 3616214 R 508767 CDS YP_001922678.1 188588526 6318702 complement(3617229..3617726) 1 NC_010723.1 identified by match to protein family HMM PF02810; hypothetical protein 3617726 6318702 CLH_3344 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922678.1 3617229 R 508767 CDS YP_001922679.1 188589469 6318932 complement(3617789..3618580) 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 3618580 6318932 CLH_3345 Clostridium botulinum E3 str. Alaska E43 metallo-beta-lactamase family protein YP_001922679.1 3617789 R 508767 CDS YP_001922680.1 188590788 6319071 complement(3618615..3619877) 1 NC_010723.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3619877 murA 6319071 murA Clostridium botulinum E3 str. Alaska E43 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001922680.1 3618615 R 508767 CDS YP_001922681.1 188587597 6318161 3620271..3620810 1 NC_010723.1 hypothetical protein 3620810 6318161 CLH_3347 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922681.1 3620271 D 508767 CDS YP_001922682.1 188588145 6319556 3620987..3621463 1 NC_010723.1 identified by match to protein family HMM PF08761; dUTPase superfamily 3621463 6319556 CLH_3348 Clostridium botulinum E3 str. Alaska E43 dUTPase superfamily YP_001922682.1 3620987 D 508767 CDS YP_001922683.1 188589073 6318687 3621653..3622084 1 NC_010723.1 identified by match to protein family HMM PF04657; hypothetical protein 3622084 6318687 CLH_3349 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922683.1 3621653 D 508767 CDS YP_001922684.1 188588640 6318894 3622142..3622960 1 NC_010723.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase domain-containing protein 3622960 6318894 CLH_3350 Clostridium botulinum E3 str. Alaska E43 metallo-beta-lactamase domain-containing protein YP_001922684.1 3622142 D 508767 CDS YP_001922685.1 188589490 6317767 3623094..3624299 1 NC_010723.1 identified by match to protein family HMM PF00082; subtilase family protein 3624299 6317767 CLH_3351 Clostridium botulinum E3 str. Alaska E43 subtilase family protein YP_001922685.1 3623094 D 508767 CDS YP_001922686.1 188587871 6317842 complement(3624409..3625542) 1 NC_010723.1 identified by match to protein family HMM PF01551; match to protein family HMM PF07501; peptidase, M23/M37 family 3625542 6317842 CLH_3352 Clostridium botulinum E3 str. Alaska E43 peptidase, M23/M37 family YP_001922686.1 3624409 R 508767 CDS YP_001922687.1 188588118 6318730 3625769..3626758 1 NC_010723.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; DNA replication protein DnaD 3626758 6318730 CLH_3353 Clostridium botulinum E3 str. Alaska E43 DNA replication protein DnaD YP_001922687.1 3625769 D 508767 CDS YP_001922688.1 188588854 6318142 3626751..3627731 1 NC_010723.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 3627731 6318142 CLH_3354 Clostridium botulinum E3 str. Alaska E43 DNA replication protein DnaC YP_001922688.1 3626751 D 508767 CDS YP_001922689.1 188589996 6319368 complement(3628932..3629516) 1 NC_010723.1 hypothetical protein 3629516 6319368 CLH_3366 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922689.1 3628932 R 508767 CDS YP_001922690.1 188588045 6320213 3629680..3630924 1 NC_010723.1 identified by match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275; hypothetical protein 3630924 6320213 CLH_3367 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922690.1 3629680 D 508767 CDS YP_001922691.1 188588903 6318040 complement(3631094..3631843) 1 NC_010723.1 identified by match to protein family HMM PF01643; acyl-ACP thioesterase 3631843 6318040 CLH_3368 Clostridium botulinum E3 str. Alaska E43 acyl-ACP thioesterase YP_001922691.1 3631094 R 508767 CDS YP_001922692.1 188589444 6317294 complement(3632050..3632232) 1 NC_010723.1 hypothetical protein 3632232 6317294 CLH_3369 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922692.1 3632050 R 508767 CDS YP_001922693.1 188590291 6318760 complement(3632335..3633621) 1 NC_010723.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 3633621 purA 6318760 purA Clostridium botulinum E3 str. Alaska E43 adenylosuccinate synthetase YP_001922693.1 3632335 R 508767 CDS YP_001922694.1 188588676 6318993 3633845..3635017 1 NC_010723.1 identified by match to protein family HMM PF00390; match to protein family HMM PF01262; match to protein family HMM PF03949; NAD-dependent malic enzyme 3635017 6318993 CLH_3371 Clostridium botulinum E3 str. Alaska E43 NAD-dependent malic enzyme YP_001922694.1 3633845 D 508767 CDS YP_001922695.1 188590426 6317247 complement(3635718..3636518) 1 NC_010723.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 3636518 proC 6317247 proC Clostridium botulinum E3 str. Alaska E43 pyrroline-5-carboxylate reductase YP_001922695.1 3635718 R 508767 CDS YP_001922696.1 188589346 6320524 3636733..3637086 1 NC_010723.1 protein phosphatase 2C 3637086 6320524 CLH_3373 Clostridium botulinum E3 str. Alaska E43 protein phosphatase 2C YP_001922696.1 3636733 D 508767 CDS YP_001922697.1 188588588 6318208 complement(3637108..3638448) 1 NC_010723.1 unwinds double stranded DNA; replicative DNA helicase 3638448 dnaB 6318208 dnaB Clostridium botulinum E3 str. Alaska E43 replicative DNA helicase YP_001922697.1 3637108 R 508767 CDS YP_001922698.1 188588300 6318028 complement(3638535..3640427) 1 NC_010723.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF05362; match to protein family HMM TIGR02903; Lon family ATP-dependent protease 3640427 lonC 6318028 lonC Clostridium botulinum E3 str. Alaska E43 Lon family ATP-dependent protease YP_001922698.1 3638535 R 508767 CDS YP_001922699.1 188590063 6319906 complement(3640443..3640886) 1 NC_010723.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 3640886 rplI 6319906 rplI Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L9 YP_001922699.1 3640443 R 508767 CDS YP_001922700.1 188589060 6317787 complement(3640889..3642829) 1 NC_010723.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH family protein 3642829 6317787 CLH_3377 Clostridium botulinum E3 str. Alaska E43 DHH family protein YP_001922700.1 3640889 R 508767 CDS YP_001922701.1 188588316 6319903 complement(3642854..3643174) 1 NC_010723.1 hypothetical protein 3643174 6319903 CLH_3378 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922701.1 3642854 R 508767 CDS YP_001922702.1 188587867 6319970 complement(3643362..3643613) 1 NC_010723.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 3643613 rpsR 6319970 rpsR Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S18 YP_001922702.1 3643362 R 508767 CDS YP_001922703.1 188589779 6319608 complement(3643635..3644078) 1 NC_010723.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-strand binding protein 3644078 6319608 CLH_3380 Clostridium botulinum E3 str. Alaska E43 single-strand binding protein YP_001922703.1 3643635 R 508767 CDS YP_001922704.1 188589519 6318062 complement(3644092..3644382) 1 NC_010723.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 3644382 rpsF 6318062 rpsF Clostridium botulinum E3 str. Alaska E43 30S ribosomal protein S6 YP_001922704.1 3644092 R 508767 CDS YP_001922705.1 188588767 6320278 complement(3644489..3644680) 1 NC_010723.1 identified by match to protein family HMM PF06107; hypothetical protein 3644680 6320278 CLH_3382 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922705.1 3644489 R 508767 CDS YP_001922706.1 188590249 6318487 complement(3644680..3645573) 1 NC_010723.1 identified by match to protein family HMM PF00924; mechanosensitive ion channel family protein 3645573 6318487 CLH_3383 Clostridium botulinum E3 str. Alaska E43 mechanosensitive ion channel family protein YP_001922706.1 3644680 R 508767 CDS YP_001922707.1 188589552 6317385 complement(3645601..3645840) 1 NC_010723.1 hypothetical protein 3645840 6317385 CLH_3384 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922707.1 3645601 R 508767 CDS YP_001922708.1 188589942 6318809 3646242..3646895 1 NC_010723.1 identified by match to protein family HMM PF01810; LysE type translocator 3646895 6318809 CLH_3385 Clostridium botulinum E3 str. Alaska E43 LysE type translocator YP_001922708.1 3646242 D 508767 CDS YP_001922709.1 188587676 6319845 3646911..3648068 1 NC_010723.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01053; match to protein family HMM TIGR01977; cysteine desulfurase 3648068 6319845 CLH_3386 Clostridium botulinum E3 str. Alaska E43 cysteine desulfurase YP_001922709.1 3646911 D 508767 CDS YP_001922710.1 188590680 6318128 3648367..3648969 1 NC_010723.1 identified by match to protein family HMM PF06866; match to protein family HMM TIGR02841; putative sporulation protein 3648969 6318128 CLH_3387 Clostridium botulinum E3 str. Alaska E43 putative sporulation protein YP_001922710.1 3648367 D 508767 CDS YP_001922711.1 188589671 6318494 complement(3649266..3649784) 1 NC_010723.1 hypothetical protein 3649784 6318494 CLH_3388 Clostridium botulinum E3 str. Alaska E43 hypothetical protein YP_001922711.1 3649266 R 508767 CDS YP_001922712.1 188589225 6320144 complement(3649825..3650703) 1 NC_010723.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; stage 0 sporulation protein J 3650703 6320144 CLH_3389 Clostridium botulinum E3 str. Alaska E43 stage 0 sporulation protein J YP_001922712.1 3649825 R 508767 CDS YP_001922713.1 188588293 6317474 complement(3650717..3651481) 1 NC_010723.1 identified by match to protein family HMM PF01656; sporulation initiation inhibitor protein soj 3651481 6317474 CLH_3390 Clostridium botulinum E3 str. Alaska E43 sporulation initiation inhibitor protein soj YP_001922713.1 3650717 R 508767 CDS YP_001922714.1 188588117 6319744 complement(3651660..3652442) 1 NC_010723.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; protein YyaA 3652442 6319744 CLH_3391 Clostridium botulinum E3 str. Alaska E43 protein YyaA YP_001922714.1 3651660 R 508767 CDS YP_001922715.1 188588844 6318141 complement(3652673..3653392) 1 NC_010723.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 3653392 gidB 6318141 gidB Clostridium botulinum E3 str. Alaska E43 16S rRNA methyltransferase GidB YP_001922715.1 3652673 R 508767 CDS YP_001922716.1 188588132 6318725 complement(3653409..3655289) 1 NC_010723.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 3655289 gidA 6318725 gidA Clostridium botulinum E3 str. Alaska E43 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001922716.1 3653409 R 508767 CDS YP_001922717.1 188590674 6318520 complement(3655299..3656669) 1 NC_010723.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 3656669 trmE 6318520 trmE Clostridium botulinum E3 str. Alaska E43 tRNA modification GTPase TrmE YP_001922717.1 3655299 R 508767 CDS YP_001922718.1 188589912 6320177 complement(3657001..3657627) 1 NC_010723.1 identified by match to protein family HMM PF01424; protein jag 3657627 6320177 CLH_3395 Clostridium botulinum E3 str. Alaska E43 protein jag YP_001922718.1 3657001 R 508767 CDS YP_001922719.1 188588551 6319545 complement(3657675..3658454) 1 NC_010723.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3658454 6319545 CLH_3396 Clostridium botulinum E3 str. Alaska E43 putative inner membrane protein translocase component YidC YP_001922719.1 3657675 R 508767 CDS YP_001922720.1 188587645 6318345 complement(3658661..3659038) 1 NC_010723.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 3659038 rnpA 6318345 rnpA Clostridium botulinum E3 str. Alaska E43 ribonuclease P YP_001922720.1 3658661 R 508767 CDS YP_001922721.1 188590195 6319606 complement(3659101..3659235) 1 NC_010723.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 3659235 rpmH 6319606 rpmH Clostridium botulinum E3 str. Alaska E43 50S ribosomal protein L34 YP_001922721.1 3659101 R 508767 CDS